Combined endoscopy, aspiration, and biopsy analysis for identifying infectious colitis in patients with ileocecal ulcers.

Science.gov (United States)

Nagata, Naoyoshi; Shimbo, Takuro; Sekine, Katsunori; Tanaka, Shouhei; Niikura, Ryota; Mezaki, Kazuhisa; Morino, Eriko; Yazaki, Hirohisa; Igari, Toru; Ohmagari, Norio; Akiyama, Junichi; Oka, Shinichi; Uemura, Naomi

2013-06-01

The ileocecal area is commonly involved in infection and inflammatory colonic diseases, but differential diagnosis can be difficult. We identified definitive endoscopic findings and a sample collection method for diagnosing infectious colitis. In a retrospective study, we analyzed data on 128 patients with ileocecal ulcer who underwent colonoscopy from 2007-2011 at the National Center for Global Health and Medicine in Tokyo, Japan. We collected information on location, size, number, and distinctive endoscopic findings and estimated diagnostic odds ratios (ORs). The sensitivities of microscopy, culture, polymerase chain reaction, and histologic methods in identifying patients with infection were compared with those of standard stool, endoscopic aspirated intestinal fluid, or biopsy analyses. Of the 128 patients, 100 had infections, and 28 had Crohn's disease, Behçet's disease, or other inflammatory diseases. Predictive endoscopic findings were as follows: for amebiasis of the cecum (OR, 17.8), with exudates (OR, 13.9) and round-shaped ulcer (OR, 5.77); for tuberculosis (TB) with transverse-shaped ulcer (OR, 175), scar (OR, 34.6), linear-shaped ulcer (OR, 23.9), or ≥10 mm (OR, 14.0); for cytomegalovirus with round-shaped ulcer (OR, 4.09); and for Campylobacter with cecal valve lesion (OR, 58.3) or ≥10 mm (OR, 10.4). The sensitivity of endoscopic sample collection was significantly higher than that of standard stool sample collection for the diagnosis of amebiasis, TB, non-TB mycobacteria, and other bacteria (P < .05). The methods that detected infection with the highest levels of sensitivity were biopsy with histology for amebiasis, biopsy with culture for TB, biopsy with polymerase chain reaction for cytomegalovirus, and aspiration of intestinal fluid with culture for Campylobacter. Combining results from endoscopic analysis with appropriate sample collection and pathogen detection methods enables infectious colitis to be differentiated from other noninfectious

THE CLINICAL MANIFESTATIONS AND COURSE OF DUODENAL ULCER DISEASE AFTER PERFORATED ULCER

Directory of Open Access Journals (Sweden)

L. A. Lyubskaya

2014-01-01

Full Text Available Objective: to compare clinical manifestations, course, mental status in duodenal ulcer (DU patients with a history of perforated ulcer and its uncomplicated course.Subjects and methods. One hundred and thirteen patents with DU were examined. Group 1 included 61 patients with uncomplicated DUand Group 2 comprised 52 patients with a history of perforated ulcer. A comparison group consisted of 20 patients who had undergone laparotomy. Physical and mental status examinations, esophagogastroduodenoscopy (EGDS, and 24-hour pH-metry were performed.Results. Classical pain syndrome was observed in 75 % of the patients with uncomplicated DU. Prior to perforation, the pain and dyspeptic syndromes were distinguished only by a significantly lower degree in Group 2; following perforation, the pain syndrome was recorded more frequently, it was more extensive, meal-unrelated, and similar to that in the patients who had undergone laparotomy and had diminished appetite (36.5 %. EGDS showed that the complicated course was accompanied by the significantly higher incidence of erosive esophagitis (21.2 %, gastritis (51.9 %, duodenitis (25.0 %, multiple ulcers (28.8 %, and larger ulcers. 24-hour pH-metry indicated that the level of hyperacidity in Group 2 was higher and the circadian intragastric pH variations were less marked than those in uncomplicated DU. The patients with a history of perforated ulcer showed a high rate of anxiety and depressive changes. Conclusion. In complicated DU, marked monotonic hyperacidity causes common erosive-ulcerative lesions in the gastroduodenal area in relatively mild pain syndrome, late referrals, and long-term ulcer healing. After perforation followed by wound closure, the pain and dyspeptic syndromes become more pronounced, which is associated with anxiety and depressive changes in the mental status, as well as with early referrals and less healing time.

Pressure Ulcer Risk in the Incontinent Patient: Analysis of Incontinence and Hospital-Acquired Pressure Ulcers From the International Pressure Ulcer Prevalence™ Survey.

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Lachenbruch, Charlie; Ribble, David; Emmons, Kirsten; VanGilder, Catherine

2016-01-01

-device-related, and located in the pelvic region. We analyzed 176,689 patients based on data collected between 2013 and 2014. Slightly less than half (n = 83,800; 47%) of patients did not have incontinence, and 92,889 (53%) were deemed to be incontinent. The prevalence of pressure ulcers was 4.1% for continent patients and 16.3% for incontinent patients; the prevalence of FAPUs was 1.6% and 6.0%, respectively. The relative risk for PU development in incontinent patients was higher than predicted by the Braden Scale risk score. As wound severity increased, the odds ratios for pressure ulcer development for incontinent patients versus continent patients also increased, especially in patients with fecal incontinence. Incontinent patients had higher Braden Scale scores and higher overall and FAPU prevalence. Incontinence was associated with an increased risk for all pressure ulcers, but especially full-thickness injuries.

Review of new shapes for higher gradients

International Nuclear Information System (INIS)

Geng, R.L.

2006-01-01

High-gradient superconducting RF (SRF) cavities are needed for energy frontier superconducting accelerators. Progress has been made over the past decades and the accelerating gradient E acc has been increased from a few MV/m to ∼42 MV/m in SRF niobium cavities. The corresponding peak RF magnetic field H pk on the niobium cavity surface is approaching the intrinsic RF critical magnetic field H crit,RF , a hard physical limit at which superconductivity breaks down. Pushing the gradient envelope further by adopting new cavity shapes with a lower ratio of H pk /E acc has been recently proposed. For a reduced H pk /E acc , a higher ultimate E acc is sustained when H pk finally strikes H crit,RF . The new cavity geometry include the re-entrant shape conceived at Cornell University and the so-called 'Low-loss' shape proposed by a DESY/JLAB/KEK collaboration. Experimental work is being pursued at Cornell, KEK and JLAB. Results of single-cell cavities are encouraging. A record gradient of 47 MV/m was first demonstrated in a 1.3 GHz re-entrant niobium cavity at Cornell University. At the time of writing, a new record of 52 MV/m has been realized with another 1.3 GHz re-entrant cavity, designed and built at Cornell and processed and tested at KEK. Single-cell low-loss cavities have reached equally high gradients in the range of 45-51 MV/m at KEK and JLAB. Owing to their higher gradient potential and the encouraging single-cell cavity results, the new cavity shapes are becoming attractive for their possible use in the international linear collider (ILC). Experimental work on multi-cell niobium cavities of new shapes is currently under active exploration

Review of new shapes for higher gradients

Science.gov (United States)

Geng, R. L.

2006-07-01

High-gradient superconducting RF (SRF) cavities are needed for energy frontier superconducting accelerators. Progress has been made over the past decades and the accelerating gradient Eacc has been increased from a few MV/m to ∼42 MV/m in SRF niobium cavities. The corresponding peak RF magnetic field Hpk on the niobium cavity surface is approaching the intrinsic RF critical magnetic field Hcrit,RF, a hard physical limit at which superconductivity breaks down. Pushing the gradient envelope further by adopting new cavity shapes with a lower ratio of Hpk/ Eacc has been recently proposed. For a reduced Hpk/ Eacc, a higher ultimate Eacc is sustained when Hpk finally strikes Hcrit,RF. The new cavity geometry include the re-entrant shape conceived at Cornell University and the so-called “Low-loss” shape proposed by a DESY/JLAB/KEK collaboration. Experimental work is being pursued at Cornell, KEK and JLAB. Results of single-cell cavities are encouraging. A record gradient of 47 MV/m was first demonstrated in a 1.3 GHz re-entrant niobium cavity at Cornell University. At the time of writing, a new record of 52 MV/m has been realized with another 1.3 GHz re-entrant cavity, designed and built at Cornell and processed and tested at KEK. Single-cell low-loss cavities have reached equally high gradients in the range of 45-51 MV/m at KEK and JLAB. Owing to their higher gradient potential and the encouraging single-cell cavity results, the new cavity shapes are becoming attractive for their possible use in the international linear collider (ILC). Experimental work on multi-cell niobium cavities of new shapes is currently under active exploration.

Orographic Flow over an Active Volcano

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Poulidis, Alexandros-Panagiotis; Renfrew, Ian; Matthews, Adrian

2014-05-01

Orographic flows over and around an isolated volcano are studied through a series of numerical model experiments. The volcano top has a heated surface, so can be thought of as "active" but not erupting. A series of simulations with different atmospheric conditions and using both idealised and realistic configurations of the Weather Research and Forecast (WRF) model have been carried out. The study is based on the Soufriere Hills volcano, located on the island of Montserrat in the Caribbean. This is a dome-building volcano, leading to a sharp increase in the surface skin temperature at the top of the volcano - up to tens of degrees higher than ambient values. The majority of the simulations use an idealised topography, in order for the results to have general applicability to similar-sized volcanoes located in the tropics. The model is initialised with idealised atmospheric soundings, representative of qualitatively different atmospheric conditions from the rainy season in the tropics. The simulations reveal significant changes to the orographic flow response, depending upon the size of the temperature anomaly and the atmospheric conditions. The flow regime and characteristic features such as gravity waves, orographic clouds and orographic rainfall patterns can all be qualitatively changed by the surface heating anomaly. Orographic rainfall over the volcano can be significantly enhanced with increased temperature anomaly. The implications for the eruptive behaviour of the volcano and resulting secondary volcanic hazards will also be discussed.

The 2014 eruptions of Pavlof Volcano, Alaska

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Waythomas, Christopher F.; Haney, Matthew M.; Wallace, Kristi; Cameron, Cheryl E.; Schneider, David J.

2017-12-22

Pavlof Volcano is one of the most frequently active volcanoes in the Aleutian Island arc, having erupted more than 40 times since observations were first recorded in the early 1800s . The volcano is located on the Alaska Peninsula (lat 55.4173° N, long 161.8937° W), near Izembek National Wildlife Refuge. The towns and villages closest to the volcano are Cold Bay, Nelson Lagoon, Sand Point, and King Cove, which are all within 90 kilometers (km) of the volcano (fig. 1). Pavlof is a symmetrically shaped stratocone that is 2,518 meters (m) high, and has about 2,300 m of relief. The volcano supports a cover of glacial ice and perennial snow roughly 2 to 4 cubic kilometers (km3) in volume, which is mantled by variable amounts of tephra fall, rockfall debris, and pyroclastic-flow deposits produced during historical eruptions. Typical Pavlof eruptions are characterized by moderate amounts of ash emission, lava fountaining, spatter-fed lava flows, explosions, and the accumulation of unstable mounds of spatter on the upper flanks of the volcano. The accumulation and subsequent collapse of spatter piles on the upper flanks of the volcano creates hot granular avalanches, which erode and melt snow and ice, and thereby generate watery debris-flow and hyperconcentrated-flow lahars. Seismic instruments were first installed on Pavlof Volcano in the early 1970s, and since then eruptive episodes have been better characterized and specific processes have been documented with greater certainty. The application of remote sensing techniques, including the use of infrasound data, has also aided the study of more recent eruptions. Although Pavlof Volcano is located in a remote part of Alaska, it is visible from Cold Bay, Sand Point, and Nelson Lagoon, making distal observations of eruptive activity possible, weather permitting. A busy air-travel corridor that is utilized by a numerous transcontinental and regional air carriers passes near Pavlof Volcano. The frequency of air travel

Models of Hawaiian volcano growth and plume structure: Implications of results from the Hawaii Scientific Drilling Project

OpenAIRE

DePaolo, D. J.; Stolper, E. M.

1996-01-01

The shapes of typical Hawaiian volcanoes are simply parameterized, and a relationship is derived for the dependence of lava accumulation rates on volcano volume and volumetric growth rate. The dependence of lava accumulation rate on time is derived by estimating the eruption rate of a volcano as it traverses the Hawaiian plume, with the eruption rate determined from a specified radial dependence of magma generation in the plume and assuming that a volcano captures melt from a circular area ce...

Tephra compositions from Late Quaternary volcanoes around the Antarctic Peninsula

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Kraus, S.

2009-12-01

Crustal extension and rifting processes opened the Bransfield Strait between the South Shetland Islands and the Antarctic Peninsula during the last 4 Ma. Similar processes on the Peninsula's eastern side are responsible for volcanism along Larsen Rift. There are at least 11 volcanic centers with known or suspected Late Pleistocene / Holocene explosive activity (Fig. 1). Fieldwork was carried out on the islands Deception, Penguin, Bridgeman and Paulet, moreover at Melville Peak (King George Is.) and Rezen Peak (Livingston Is.). Of special importance is the second ever reported visit and sampling at Sail Rock, and the work on never before visited outcrops on the northern slopes and at the summit of Cape Purvis volcano (Fig. 1). The new bulk tephra ICP-MS geochemical data provide a reliable framework to distinguish the individual volcanic centers from each other. According to their Mg-number, Melville Peak and Penguin Island represent the most primitive magma source. Nb/Y ratios higher than 0.67 in combination with elevated Th/Yb and Ta/Yb ratios and strongly enriched LREE seem to be diagnostic to distinguish the volcanoes located along the Larsen Rift from those associated with Bransfield Rift. Sr/Y ratios discriminate between the individual Larsen Rift volcanoes, Paulet Island showing considerably higher values than Cape Purvis volcano. Along Bransfield Rift, Bridgeman Island and Melville Peak have notably lower Nb/Y and much higher Th/Nb than Deception Island, Penguin Island and Sail Rock. The latter displays almost double the Th/Yb ratio as compared to Deception Island, and also much higher LREE enrichment but extraordinarily low Ba/Th, discriminating it from Penguin Island. Such extremely low Ba/Th ratios are also typical for Melville Peak, but for none of the other volcanoes. Penguin Island has almost double the Ba/Th and Sr/Y ratios higher than any other investigated volcano. Whereas the volcanoes located in the northern part of Bransfield Strait have Zr

Volcano morphometry and volume scaling on Venus

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Garvin, J. B.; Williams, R. S., Jr.

1994-01-01

A broad variety of volcanic edifices have been observed on Venus. They ranged in size from the limits of resolution of the Magellan SAR (i.e., hundreds of meters) to landforms over 500 km in basal diameter. One of the key questions pertaining to volcanism on Venus concerns the volume eruption rate or VER, which is linked to crustal productivity over time. While less than 3 percent of the surface area of Venus is manifested as discrete edifices larger than 50 km in diameter, a substantial component of the total crustal volume of the planet over the past 0.5 Ga is related to isolated volcanoes, which are certainly more easily studied than the relatively diffusely defined plains volcanic flow units. Thus, we have focused our efforts on constraining the volume productivity of major volcanic edifices larger than 100 km in basal diameter. Our approach takes advantage of the topographic data returned by Magellan, as well as our database of morphometric statistics for the 20 best known lava shields of Iceland, plus Mauna Loa of Hawaii. As part of this investigation, we have quantified the detailed morphometry of nearly 50 intermediate to large scale edifices, with particular attention to their shape systematics. We found that a set of venusian edifices which include Maat, Sapas, Tepev, Sif, Gula, a feature at 46 deg S, 215 deg E, as well as the shield-like structure at 10 deg N, 275 deg E are broadly representative of the approx. 400 volcanic landforms larger than 50 km. The cross-sectional shapes of these 7 representative edifices range from flattened cones (i.e., Sif) similar to classic terrestrial lava shields such as Mauna Loa and Skjaldbreidur, to rather dome-like structures which include Maat and Sapas. The majority of these larger volcanoes surveyed as part of our study displayed cross-sectional topographies with paraboloidal shaped, in sharp contrast with the cone-like appearance of most simple terrestrial lava shields. In order to more fully explore the

A porous flow model for the geometrical form of volcanoes - Critical comments

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Wadge, G.; Francis, P.

1982-01-01

A critical evaluation is presented of the assumptions on which the mathematical model for the geometrical form of a volcano arising from the flow of magma in a porous medium of Lacey et al. (1981) is based. The lack of evidence for an equipotential surface or its equivalent in volcanoes prior to eruption is pointed out, and the preference of volcanic eruptions for low ground is attributed to the local stress field produced by topographic loading rather than a rising magma table. Other difficulties with the model involve the neglect of the surface flow of lava under gravity away from the vent, and the use of the Dupuit approximation for unconfined flow and the assumption of essentially horizontal magma flow. Comparisons of model predictions with the shapes of actual volcanoes reveal the model not to fit lava shield volcanoes, for which the cone represents the solidification of small lava flows, and to provide a poor fit to composite central volcanoes.

Evolution of deep crustal magma structures beneath Mount Baekdu volcano (MBV) intraplate volcano in northeast Asia

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Rhie, J.; Kim, S.; Tkalcic, H.; Baag, S. Y.

2017-12-01

Heterogeneous features of magmatic structures beneath intraplate volcanoes are attributed to interactions between the ascending magma and lithospheric structures. Here, we investigate the evolution of crustal magmatic stuructures beneath Mount Baekdu volcano (MBV), which is one of the largest continental intraplate volcanoes in northeast Asia. The result of our seismic imaging shows that the deeper Moho depth ( 40 km) and relatively higher shear wave velocities (>3.8 km/s) at middle-to-lower crustal depths beneath the volcano. In addition, the pattern at the bottom of our model shows that the lithosphere beneath the MBV is shallower (interpret the observations as a compositional double layering of mafic underplating and a overlying cooled felsic structure due to fractional crystallization of asthenosphere origin magma. To achieve enhanced vertical and horizontal model coverage, we apply two approaches in this work, including (1) a grid-search based phase velocity measurement using real-coherency of ambient noise data and (2) a transdimensional Bayesian joint inversion using multiple ambient noise dispersion data.

Preventing pressure ulcers on the heel: a Canadian cost study.

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Torra I Bou, Joan-Enric; Rueda López, Justo; Camañes, Gemma; Herrero Narváez, Elias; Blanco Blanco, Joan; Ballesté Torralba, Jordi; Martinez-Esparza, Elvira Hernández; García, Lorena San Miguel; Soriano, José Verdú

2009-01-01

An adaptation of a clinical study of 130 patients at risk of developing a pressure ulcer on the heels was performed using Canadian costs. The aim of the study was to compare the cost effectiveness of a specially shaped hydrocellular dressing (Allevyn Heel) versus that of a protective heel bandage (Soffban and gauze) in pressure ulcer prevention over an 8-week period.

Cyclic Activity of Mud Volcanoes: Evidences from Trinidad (SE Caribbean)

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Deville, E.

2007-12-01

Fluid and solid transfer in mud volcanoes show different phases of activity, including catastrophic events followed by periods of relative quiescence characterized by moderate activity. This can be notably shown by historical data onshore Trinidad. Several authors have evoked a possible link between the frequencies of eruption of some mud volcanoes and seismic activity, but in Trinidad there is no direct correlation between mud eruptions and seisms. It appears that each eruptive mud volcano has its own period of catastrophic activity, and this period is highly variable from one volcano to another. The frequency of activity of mud volcanoes seems essentially controlled by local pressure regime within the sedimentary pile. At the most, a seism can, in some cases, activate an eruption close to its term. The dynamics of expulsion of the mud volcanoes during the quiescence phases has been studied notably from temperature measurements within the mud conduits. The mud temperature is concurrently controlled by, either, the gas flux (endothermic gas depressurizing induces a cooling effect), or by the mud flux (mud is a vector for convective heat transfer). Complex temperature distribution was observed in large conduits and pools. Indeed, especially in the bigger pools, the temperature distribution characterizes convective cells with an upward displacement of mud above the deep outlet, and ring-shaped rolls associated with the burial of the mud on the flanks of the pools. In simple, tube-like shaped, narrow conduits, the temperature is more regular, but we observed different types of profiles, with either downward increasing or decreasing temperatures. If the upward flow of mud would be regular, we should expect increasing temperatures and progressively decreasing gradient with depth within the conduits. However, the variable measured profiles from one place to another, as well as time-variable measured temperatures within the conduits and especially, at the base of the

A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers

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Chung, Chen-Shuan; Chiang, Tsung-Hsien; Lee, Yi-Chia

2015-01-01

An idiopathic peptic ulcer is defined as an ulcer with unknown cause or an ulcer that appears to arise spontaneously. The first step in treatment is to exclude common possible causes, including Helicobacter pylori infection, infection with other pathogens, ulcerogenic drugs, and uncommon diseases with upper gastrointestinal manifestations. When all known causes are excluded, a diagnosis of idiopathic peptic ulcer can be made. A patient whose peptic ulcer is idiopathic may have a higher risk for complicated ulcer disease, a poorer response to gastric acid suppressants, and a higher recurrence rate after treatment. Risk factors associated with this disease may include genetic predisposition, older age, chronic mesenteric ischemia, smoking, concomitant diseases, a higher American Society of Anesthesiologists score, and higher stress. Therefore, the diagnosis and management of emerging disease should systematically explore all known causes and treat underlying disease, while including regular endoscopic surveillance to confirm ulcer healing and the use of proton-pump inhibitors on a case-by-case basis. PMID:26354049

Instrumentation Recommendations for Volcano Monitoring at U.S. Volcanoes Under the National Volcano Early Warning System

Science.gov (United States)

Moran, Seth C.; Freymueller, Jeff T.; LaHusen, Richard G.; McGee, Kenneth A.; Poland, Michael P.; Power, John A.; Schmidt, David A.; Schneider, David J.; Stephens, George; Werner, Cynthia A.; White, Randall A.

2008-01-01

As magma moves toward the surface, it interacts with anything in its path: hydrothermal systems, cooling magma bodies from previous eruptions, and (or) the surrounding 'country rock'. Magma also undergoes significant changes in its physical properties as pressure and temperature conditions change along its path. These interactions and changes lead to a range of geophysical and geochemical phenomena. The goal of volcano monitoring is to detect and correctly interpret such phenomena in order to provide early and accurate warnings of impending eruptions. Given the well-documented hazards posed by volcanoes to both ground-based populations (for example, Blong, 1984; Scott, 1989) and aviation (for example, Neal and others, 1997; Miller and Casadevall, 2000), volcano monitoring is critical for public safety and hazard mitigation. Only with adequate monitoring systems in place can volcano observatories provide accurate and timely forecasts and alerts of possible eruptive activity. At most U.S. volcanoes, observatories traditionally have employed a two-component approach to volcano monitoring: (1) install instrumentation sufficient to detect unrest at volcanic systems likely to erupt in the not-too-distant future; and (2) once unrest is detected, install any instrumentation needed for eruption prediction and monitoring. This reactive approach is problematic, however, for two reasons. 1. At many volcanoes, rapid installation of new ground-1. based instruments is difficult or impossible. Factors that complicate rapid response include (a) eruptions that are preceded by short (hours to days) precursory sequences of geophysical and (or) geochemical activity, as occurred at Mount Redoubt (Alaska) in 1989 (24 hours), Anatahan (Mariana Islands) in 2003 (6 hours), and Mount St. Helens (Washington) in 1980 and 2004 (7 and 8 days, respectively); (b) inclement weather conditions, which may prohibit installation of new equipment for days, weeks, or even months, particularly at

Correlates of Bacterial Ulcers and Acute HSV-2 Infection among Men with Genital Ulcer Disease in South Africa: Age, Recent Sexual Behaviors, and HIV.

Science.gov (United States)

Leichliter, Jami S; Lewis, David A; Paz-Bailey, Gabriela

2016-01-01

Data from baseline surveys and STI/HIV laboratory tests (n=615 men) were used to examine correlates of bacterial ulcers ( Treponema pallidum , Haemophilus ducreyi , or Chlamydia trachomatis L1-L3 detected in ulcer) and acute HSV-2 ulcers (HSV-2 positive ulcer specimen, HSV-2 sero-negative, and negative for bacterial pathogens) vs. recurrent HSV-2 ulcers (sero-positive), separately. Compared to men with recurrent HSV-2 ulcers, men with bacterial ulcers had larger ulcers but were less likely to be HIV-positive whereas men with acute HSV-2 ulcers were younger with fewer partners. Acute HIV was higher among men with bacterial and acute HSV-2 ulcers; the difference was not statistically significant.

Field-trip guide to the geologic highlights of Newberry Volcano, Oregon

Science.gov (United States)

Jensen, Robert A.; Donnelly-Nolan, Julie M.

2017-08-09

Newberry Volcano and its surrounding lavas cover about 3,000 square kilometers (km2) in central Oregon. This massive, shield-shaped, composite volcano is located in the rear of the Cascades Volcanic Arc, ~60 km east of the Cascade Range crest. The volcano overlaps the northwestern corner of the Basin and Range tectonic province, known locally as the High Lava Plains, and is strongly influenced by the east-west extensional environment. Lava compositions range from basalt to rhyolite. Eruptions began about half a million years ago and built a broad composite edifice that has generated more than one caldera collapse event. At the center of the volcano is the 6- by 8-km caldera, created ~75,000 years ago when a major explosive eruption of compositionally zoned tephra led to caldera collapse, leaving the massive shield shape visible today. The volcano hosts Newberry National Volcanic Monument, which encompasses the caldera and much of the northwest rift zone where mafic eruptions occurred about 7,000 years ago. These young lava flows erupted after the volcano was mantled by the informally named Mazama ash, a blanket of volcanic ash generated by the eruption that created Crater Lake about 7,700 years ago. This field trip guide takes the visitor to a variety of easily accessible geologic sites in Newberry National Volcanic Monument, including the youngest and most spectacular lava flows. The selected sites offer an overview of the geologic story of Newberry Volcano and feature a broad range of lava compositions. Newberry’s most recent eruption took place about 1,300 years ago in the center of the caldera and produced tephra and lava of rhyolitic composition. A significant mafic eruptive event occurred about 7,000 years ago along the northwest rift zone. This event produced lavas ranging in composition from basalt to andesite, which erupted over a distance of 35 km from south of the caldera to Lava Butte where erupted lava flowed west to temporarily block the Deschutes

The association of peptic ulcer and schizophrenia: a population-based study.

Science.gov (United States)

Liao, Chun-Hui; Chang, Chen-Shu; Chang, Shih-Ni; Muo, Chih-Hsin; Lane, Hsien-Yuan; Sung, Fung-Chang; Kao, Chia-Hung

2014-12-01

The association of schizophrenia with peptic ulcer is not conclusive. In the last 30years, there has been little evaluation of peptic ulcer among schizophrenia patients. To explore the relation of peptic ulcer and schizophrenia during this new phase, we used the data from Taiwan insurance claims, identified 1496 schizophrenia patients (ICD-9-CM: 295) and selected 5984 non-schizophrenia controls that were frequency-matched by sex, age, and index year with schizophrenia patients during the years 1998-2001. All subjects were free of peptic ulcer at baseline. We measured incidences of peptic ulcer (ICD-9-CM: 531-534) until the end of 2009. The incidence of peptic ulcer was 1.27 times higher in schizophrenia patients than in the control group (12.1vs. 9.52 per 1000 person-years). Patients are at higher risk taking anti-depression, anxiolytic and hypnotics or non-steroidal anti-inflammatory drugs. After controlling the confounding factors, schizophrenia patients had no significant increase incidence of peptic ulcer. Schizophrenia patients have a slightly higher risk of peptic ulcer compared to the general population. This might be due to a higher rate of taking anti-depression, anxiolytic and hypnotics or non-steroidal anti-inflammatory drugs and alcoholism among this group. Copyright © 2014 Elsevier Inc. All rights reserved.

Peptic ulcer frequency differences related to h. Pylori or aines.

Science.gov (United States)

Carli, Diego Michelon de; Pires, Rafael Cardoso; Rohde, Sofia Laura; Kavalco, Caroline Mayara; Fagundes, Renato Borges

2015-01-01

Peptic ulcer etiology has been changing because of H. pylori decline. To estimate peptic ulcer prevalence in 10 years-interval and compare the association with H. pylori and use of non-steroidal anti-inflammatory drugs. Methods Records assessment in two periods: A (1997-2000) and B (2007-2010), searching for peptic ulcer, H. pylori infection and non-steroidal anti-inflammatory drugs use. Peptic ulcer occurred in 30.35% in A and in 20.19% in B. H. pylori infection occurred in 73.3% cases in A and in 46.4% in B. Non-steroidal anti-inflammatory drugs use was 3.5% in A and 13.3% in B. Neither condition occurred in 10.4% and 20.5% in A and B respectively. Comparing both periods, we observed reduction of peptic ulcer associated to H. pylori (P=0.000), increase of peptic ulcer related to non-steroidal anti-inflammatory drugs (P=0.000) and idiopathic peptic ulcer (P=0.002). The concurrent association of H. pylori and non-steroidal anti-inflammatory drugs was also higher in B (P=0.002). Rates of gastric ulcer were higher and duodenal ulcer lower in the second period. After 10 years, the prevalence of peptic ulcer decreased, as well as ulcers related to H. pylori whereas ulcers associated to non-steroidal anti-inflammatory drugs increased. There was an inversion in the pattern of gastric and duodenal ulcer and a rise of idiopathic peptic ulcer.

PEPTIC ULCER FREQUENCY DIFFERENCES RELATED TO H. PYLORI OR AINES

Directory of Open Access Journals (Sweden)

Diego Michelon de CARLI

Full Text Available Background Peptic ulcer etiology has been changing because of H. pylori decline. Objectives To estimate peptic ulcer prevalence in 10 years-interval and compare the association with H. pylori and use of non-steroidal anti-inflammatory drugs. Methods Records assessment in two periods: A (1997-2000 and B (2007-2010, searching for peptic ulcer, H. pylori infection and non-steroidal anti-inflammatory drugs use. Results Peptic ulcer occurred in 30.35% in A and in 20.19% in B. H. pylori infection occurred in 73.3% cases in A and in 46.4% in B. Non-steroidal anti-inflammatory drugs use was 3.5% in A and 13.3% in B. Neither condition occurred in 10.4% and 20.5% in A and B respectively. Comparing both periods, we observed reduction of peptic ulcer associated to H. pylori (P=0.000, increase of peptic ulcer related to non-steroidal anti-inflammatory drugs (P=0.000 and idiopathic peptic ulcer (P=0.002. The concurrent association of H. pylori and non-steroidal anti-inflammatory drugs was also higher in B (P=0.002. Rates of gastric ulcer were higher and duodenal ulcer lower in the second period. Conclusions After 10 years, the prevalence of peptic ulcer decreased, as well as ulcers related to H. pylori whereas ulcers associated to non-steroidal anti-inflammatory drugs increased. There was an inversion in the pattern of gastric and duodenal ulcer and a rise of idiopathic peptic ulcer.

Measurements of radon and chemical elements: Popocatepetl volcano

International Nuclear Information System (INIS)

Pena, P.; Segovia, N.; Lopez, B.; Reyes, A.V.; Armienta, M.A.; Valdes, C.; Mena, M.; Seidel, J.L.; Monnin, M.

2002-01-01

The Popocatepetl volcano is a higher risk volcano located at 60 Km from Mexico City. Radon measurements on soil in two fixed seasons located in the north slope of volcano were carried out. Moreover the radon content, major chemical elements and tracks in water samples of three springs was studied. The radon of soil was determined with solid detectors of nuclear tracks (DSTN). The radon in subterranean water was evaluated through the liquid scintillation method and it was corroborated with an Alpha Guard equipment. The major chemical elements were determined with conventional chemical methods and the track elements were measured using an Icp-Ms equipment. The radon on soil levels were lower, indicating a moderate diffusion of the gas across the slope of the volcano. The radon in subterranean water shown few changes in relation with the active scene of the volcano. The major chemical elements and tracks showed a stable behavior during the sampling period. (Author)

Peptic Ulcer Disease Risk in Chronic Kidney Disease: Ten-Year Incidence, Ulcer Location, and Ulcerogenic Effect of Medications

Science.gov (United States)

Liang, Chih-Chia; Muo, Chih-Hsin; Wang, I-Kuan; Chang, Chiz-Tzung; Chou, Che-Yi; Liu, Jiung-Hsiun; Yen, Tzung-Hai; Huang, Chiu-Ching; Chung, Chi-Jung

2014-01-01

Objectives We aimed at determining peptic ulcer disease (PUD) incidence among chronic kidney disease (CKD) patients during 1998–2008, compared to patients without CKD, and at examining associations between CKD and PUD. Methods Data for 1998–2008 were extracted from the National Health Insurance Research Database in Taiwan. The annual PUD incidence (cases per thousand persons per year) was calculated separately for patients with and without CKD. Characteristics of patients with newly diagnosed PUD (n = 16322) were compared to those of a control group without PUD (n = 32644). The 2 groups were matched for age, sex, and index year. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression. Results Over the 10-year period, the PUD incidence was ∼10–12 times higher in CKD patients than in those without CKD. Its incidence in elderly CKD patients increased rapidly over time. For CKD patients, most PUD events (>95%) were managed during hospitalization. Peptic ulcer risk, adjusted for all potential confounders, was much higher in CKD patients undergoing hemodialysis (adjusted OR, 9.74; 95% CI, 7.11–13.31). Maintenance hemodialysis patients were 2 times more likely to have gastric ulcers than duodenal ulcers, while CKD patients not on dialysis had similar risks for both. There were no significant interactions between medications and CKD status on the peptic ulcer risk. Unlike CKD patients on nonsteroidal anti-inflammatory drugs and clopidogrel, those on aspirin did not have a higher peptic ulcer risk (adjusted OR, 0.88; 95% CI, 0.44–1.77). Conclusions CKD patients have a substantially increased PUD risk, and the majority of CKD patients with PUD require hospital management. Further, peptic ulcer risk is affected by hemodialysis therapy, patient status (inpatient vs. outpatient), and ulcerogenic medications. PMID:24498412

K-Ar ages of the Hiruzen volcano group and the Daisen volcano

International Nuclear Information System (INIS)

Tsukui, Masashi; Nishido, Hirotsugu; Nagao, Keisuke.

1985-01-01

Seventeen volcanic rocks of the Hiruzen volcano group and the Daisen volcano, in southwest Japan, were dated by the K-Ar method to clarify the age of volcanic activity in this region and the evolution of these composite volcanoes. The eruption ages of the Hiruzen volcano group were revealed to be about 0.9 Ma to 0.5 Ma, those of the Daisen volcano to be about 1 Ma to very recent. These results are consistent with geological and paleomagnetic data of previous workers. Effusion of lavas in the area was especially vigorous at 0.5+-0.1 Ma. It was generally considered that the Hiruzen volcano group had erupted during latest Pliocene to early Quaternary and it is older than the Daisen volcano, mainly from their topographic features. However, their overlapping eruption ages and petrographical similarities of the lavas of the Hiruzen volcano group and the Daisen volcano suggest that they may be included in the Daisen volcano in a broad sense. The aphyric andesite, whose eruption age had been correlated to Wakurayama andesite (6.34+-0.19 Ma) in Matsue city and thought to be the basement of the Daisen volcano, was dated to be 0.46+-0.04 Ma. It indicates that petrographically similar aphyric andesite erupted sporadically at different time and space in the San'in district. (author)

Design and evaluation of famotidine mucoadhesive nanoparticles for aspirin induced ulcer treatment

International Nuclear Information System (INIS)

Patel, Dhaval J.; Patel, Jayvadan K.

2013-01-01

The present study was performed to design and evaluate the famotidine loaded mucoadhesive nanosuspension for aspirin induced ulcer. A 3-factor, 3-level Box-Behnken design was applied to study the effects of amount of the beads (X 1 ), PVPK-30(X 2 ) and Tween-80 (X 3 ) on the particle size (Y 1 ), and cumulative percentage drug released after 1h (Y 2 ). The optimization was performed using the desirability function and contour plots. The scanning electron microscopy (SEM) showed the nanoparticles as spherical in shape. The differential scanning calorimetry (DSC) analysis indicated that there was substantial crystallinity change in the nanoparticle compared with the pure drug. Ex-vivo mucoadhesion study showed that famotidine mucoadhesive nanoparticles possessed higher mucoadhesion than the famotidine nanoparticles. The in vivo studies on aspirin-induced rats indicated the lowering in ulcer index for famotidine mucoadhesive nanoparticles was 0.46 ±0.011, which was significantly better than the effect of traditional famotidine suspension (0.66±0.035). Famotidine mucoadhesive nanosuspension could be prepared using the media milling technique and allowing significant reduction in ulcer index compared to famotidine suspension. (author)

Design and evaluation of famotidine mucoadhesive nanoparticles for aspirin induced ulcer treatment

Energy Technology Data Exchange (ETDEWEB)

Patel, Dhaval J., E-mail: dhaval6668@gmail.com [Department of Pharmaceutics, Saraswati Institute of Pharmaceutical Sciences, Gujarat (India); Patel, Jayvadan K. [Department of Pharmaceutics, Nootan Pharmacy College, Visnagar (India)

2013-03-15

The present study was performed to design and evaluate the famotidine loaded mucoadhesive nanosuspension for aspirin induced ulcer. A 3-factor, 3-level Box-Behnken design was applied to study the effects of amount of the beads (X{sub 1}), PVPK-30(X{sub 2}) and Tween-80 (X{sub 3}) on the particle size (Y{sub 1}), and cumulative percentage drug released after 1h (Y{sub 2}). The optimization was performed using the desirability function and contour plots. The scanning electron microscopy (SEM) showed the nanoparticles as spherical in shape. The differential scanning calorimetry (DSC) analysis indicated that there was substantial crystallinity change in the nanoparticle compared with the pure drug. Ex-vivo mucoadhesion study showed that famotidine mucoadhesive nanoparticles possessed higher mucoadhesion than the famotidine nanoparticles. The in vivo studies on aspirin-induced rats indicated the lowering in ulcer index for famotidine mucoadhesive nanoparticles was 0.46 {+-}0.011, which was significantly better than the effect of traditional famotidine suspension (0.66{+-}0.035). Famotidine mucoadhesive nanosuspension could be prepared using the media milling technique and allowing significant reduction in ulcer index compared to famotidine suspension. (author)

Ring and Volcano Structures Formed by a Metal Dipyrromethene Complex

Energy Technology Data Exchange (ETDEWEB)

Son, Seung Bae; Hahn, Jae Ryang [Chonbuk National Univ., Jeonju (Korea, Republic of); Miao, Qing; Shin, Jiyoung; Dolphin, David [Univ. of British Columbia, Columbia (Canada)

2014-06-15

Dichloromethane liquid droplets containing a cobalt dipyrromethene trimer deposited on a graphite surface were found to form coffee ring, toroid ring, or volcano dot structures due to the redistribution of the solute during solvent evaporation. The shapes and size distributions of the ring structures depended on the drying temperature. The shape differences were attributed to the fact that the solvent evaporation rate controlled the self-assembly process that yielded the coffee stain and pinhole structures.

What Are Volcano Hazards?

Science.gov (United States)

... Sheet 002-97 Revised March 2008 What Are Volcano Hazards? Volcanoes give rise to numerous geologic and ... as far as 15 miles from the volcano. Volcano Landslides A landslide or debris avalanche is a ...

[Effect of heijiang pill on radiation skin ulcer in rats].

Science.gov (United States)

Fu, Qi; Yang, Yang; Xu, Yong-Mei

2008-05-01

To investigate the relationship between single dosage of 60Co radiation and the degree of radiation-induced skin ulcers, and to evaluate the curative effect of Heijiang Pill (HJP) on skin ulcer induced by various dosages of radiation in rats. Sixty-six Wistar female rats were randomly divided into three groups, the blank control group (n = 6) and the two radiation groups, each 30 rats, with their right hind leg exposed respectively to 60 Gy and 40 Gy of 60 Co radiation. The time of emergence and degree of skin ulcer were recorded. Then rats in the two radiation groups were subdivided into the HJP group, the Ethacridine group and the model group, 10 in each group, they received corresponding treatment after ulceration, and the incidence, pathology, cure rate and cure time of skin ulcer were observed in the 90 days of observation. The incidence of skin ulcer was higher and occurred earlier in rats radiated with 60 Gy than that with 40 Gy (P ulcer healing rate in rats treated with HJP was higher than that treated with Ethacridine (P cure time in the HJP group was shorter (P ulcers. HJP can effectively cure radiation skin ulcer, and the effect is especially significant on the ulcer induced by low dose radiation.

Space Radar Image of Colombian Volcano

Science.gov (United States)

1999-01-01

This is a radar image of a little known volcano in northern Colombia. The image was acquired on orbit 80 of space shuttle Endeavour on April 14, 1994, by the Spaceborne Imaging Radar C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR). The volcano near the center of the image is located at 5.6 degrees north latitude, 75.0 degrees west longitude, about 100 kilometers (65 miles) southeast of Medellin, Colombia. The conspicuous dark spot is a lake at the bottom of an approximately 3-kilometer-wide (1.9-mile) volcanic collapse depression or caldera. A cone-shaped peak on the bottom left (northeast rim) of the caldera appears to have been the source for a flow of material into the caldera. This is the northern-most known volcano in South America and because of its youthful appearance, should be considered dormant rather than extinct. The volcano's existence confirms a fracture zone proposed in 1985 as the northern boundary of volcanism in the Andes. The SIR-C/X-SAR image reveals another, older caldera further south in Colombia, along another proposed fracture zone. Although relatively conspicuous, these volcanoes have escaped widespread recognition because of frequent cloud cover that hinders remote sensing imaging in visible wavelengths. Four separate volcanoes in the Northern Andes nations ofColombia and Ecuador have been active during the last 10 years, killing more than 25,000 people, including scientists who were monitoring the volcanic activity. Detection and monitoring of volcanoes from space provides a safe way to investigate volcanism. The recognition of previously unknown volcanoes is important for hazard evaluations because a number of major eruptions this century have occurred at mountains that were not previously recognized as volcanoes. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of

Visions of Volcanoes

Directory of Open Access Journals (Sweden)

David M. Pyle

2017-12-01

Full Text Available The long nineteenth century marked an important transition in the understanding of the nature of combustion and fire, and of volcanoes and the interior of the earth. It was also a period when dramatic eruptions of Vesuvius lit up the night skies of Naples, providing ample opportunities for travellers, natural philosophers, and early geologists to get up close to the glowing lavas of an active volcano. This article explores written and visual representations of volcanoes and volcanic activity during the period, with the particular perspective of writers from the non-volcanic regions of northern Europe. I explore how the language of ‘fire’ was used in both first-hand and fictionalized accounts of peoples’ interactions with volcanoes and experiences of volcanic phenomena, and see how the routine or implicit linkage of ‘fire’ with ‘combustion’ as an explanation for the deep forces at play within and beneath volcanoes slowly changed as the formal scientific study of volcanoes developed. I show how Vesuvius was used as a ‘model’ volcano in science and literature and how, later, following devastating eruptions in Indonesia and the Caribbean, volcanoes took on a new dimension as contemporary agents of death and destruction.

Support surfaces for pressure ulcer prevention.

Science.gov (United States)

McInnes, Elizabeth; Jammali-Blasi, Asmara; Bell-Syer, Sally E M; Dumville, Jo C; Middleton, Victoria; Cullum, Nicky

2015-09-03

, although two trials indicated that foam overlays caused adverse skin changes. Meta-analysis of three trials suggest that Australian standard medical sheepskins prevent pressure ulcers (RR 0.56 95% CI 0.32 to 0.97).  People at high risk of developing pressure ulcers should use higher-specification foam mattresses rather than standard hospital foam mattresses. The relative merits of higher-specification constant low-pressure and alternating-pressure support surfaces for preventing pressure ulcers are unclear, but alternating-pressure mattresses may be more cost effective than alternating-pressure overlays in a UK context. Medical grade sheepskins are associated with a decrease in pressure ulcer development. Organisations might consider the use of some forms of pressure relief for high risk patients in the operating theatre.

[Non-Helicobacter pylori, Non-nonsteroidal Anti-inflammatory Drug Peptic Ulcer Disease].

Science.gov (United States)

Chang, Young Woon

2016-06-25

Non-Helicobacter pylori, non-NSAID peptic ulcer disease (PUD), termed idiopathic PUD, is increasing in Korea. Diagnosis is based on exclusion of common causes such as H. pylori infection, infection with other pathogens, surreptitious ulcerogenic drugs, malignancy, and uncommon systemic diseases with upper gastrointestinal manifestations. The clinical course of idiopathic PUD is delayed ulcer healing, higher recurrence, higher re-bleeding after initial ulcer healing, and higher mortality than the other types of PUD. Genetic predisposition, older age, chronic mesenteric ischemia, cigarette smoking, concomitant systemic diseases, and psychological stress are considered risk factors for idiopathic PUD. Diagnosis of idiopathic PUD should systematically explore all possible causes. Management of this disease is to treat underlying disease followed by regular endoscopic surveillance to confirm ulcer healing. Continuous proton pump inhibitor therapy is an option for patients who respond poorly to the standard ulcer regimen.

Impact of Facial Conformation on Canine Health: Corneal Ulceration

Science.gov (United States)

Packer, Rowena M. A.; Hendricks, Anke; Burn, Charlotte C.

2015-01-01

Concern has arisen in recent years that selection for extreme facial morphology in the domestic dog may be leading to an increased frequency of eye disorders. Corneal ulcers are a common and painful eye problem in domestic dogs that can lead to scarring and/or perforation of the cornea, potentially causing blindness. Exaggerated juvenile-like craniofacial conformations and wide eyes have been suspected as risk factors for corneal ulceration. This study aimed to quantify the relationship between corneal ulceration risk and conformational factors including relative eyelid aperture width, brachycephalic (short-muzzled) skull shape, the presence of a nasal fold (wrinkle), and exposed eye-white. A 14 month cross-sectional study of dogs entering a large UK based small animal referral hospital for both corneal ulcers and unrelated disorders was carried out. Dogs were classed as affected if they were diagnosed with a corneal ulcer using fluorescein dye while at the hospital (whether referred for this disorder or not), or if a previous diagnosis of corneal ulcer(s) was documented in the dogs’ histories. Of 700 dogs recruited, measured and clinically examined, 31 were affected by corneal ulcers. Most cases were male (71%), small breed dogs (mean± SE weight: 11.4±1.1 kg), with the most commonly diagnosed breed being the Pug. Dogs with nasal folds were nearly five times more likely to be affected by corneal ulcers than those without, and brachycephalic dogs (craniofacial ratio dogs. A 10% increase in relative eyelid aperture width more than tripled the ulcer risk. Exposed eye-white was associated with a nearly three times increased risk. The results demonstrate that artificially selecting for these facial characteristics greatly heightens the risk of corneal ulcers, and such selection should thus be discouraged to improve canine welfare. PMID:25969983

Comparison with Offshore and Onshore Mud Volcanoes in the Southwestern Taiwan

Science.gov (United States)

Chen, Y. H.; Su, C. C.; Chen, T. T.; Liu, C. S.; Paull, C. K.; Caress, D. W.; Gwiazda, R.; Lundsten, E. M.; Hsu, H. H.

2017-12-01

The offshore area southwest (SW) of Taiwan is on the convergent boundary between the Eurasian and Philippine Sea plates. The plate convergence manifests in this unique geological setting as a fold-and-thrust-belt. Multi-channel seismic profiles, and bathymetry and gravity anomaly data collected from Taiwan offshore to the SW show the presence of a large amount of mud volcanoes and diapirs with NE-SW orientations. In the absence of comprehensive sampling and detailed geochemistry data from submarine mud volcanoes, the relation between onshore and offshore mud volcanoes remains ambiguous. During two MBARI and IONTU joint cruises conducted in 2017 we collected high-resolution multibeam bathymetry data (1-m-resolution) and chirp sub-bottom profiles with an autonomous underwater vehicle (AUV) from submarine Mud Volcano III (MV3), and obtained precisely located samples and video observations with a remotely operated vehicle (ROV). MV3 is an active submarine mud volcano at 465 m water depth offshore SW Taiwan. This cone-shape mud volcano is almost 780 m wide, 150 m high, with 8° slopes, and a 30 m wide mound on the top. Several linear features are observed in the southwest of the mound, and these features are interpreted as a series of marks caused by rolling rocks that erupted from the top of MV3. We collected three rocks and push cores from MV3 and its top with the ROV, in order to compare their chemical and mineralogical composition to that of samples collected from mud volcanoes along the Chishan fault. The surface and X-radiography imaging, 210Pb chronology, grain size and X-ray diffractometer analyses were conducted to compare geochemical and sedimentary properties of offshore and onshore mud volcanoes. The results indicate that the offshore and onshore mud volcanoes have similar characteristics. We suggest that offshore and onshore mud volcanoes of SW Taiwan are no different in the source of their materials and their mechanism of creation and evolution.

Magmatic architecture within a rift segment: Articulate axial magma storage at Erta Ale volcano, Ethiopia

Science.gov (United States)

Xu, Wenbin; Rivalta, Eleonora; Li, Xing

2017-10-01

Understanding the magmatic systems beneath rift volcanoes provides insights into the deeper processes associated with rift architecture and development. At the slow spreading Erta Ale segment (Afar, Ethiopia) transition from continental rifting to seafloor spreading is ongoing on land. A lava lake has been documented since the twentieth century at the summit of the Erta Ale volcano and acts as an indicator of the pressure of its magma reservoir. However, the structure of the plumbing system of the volcano feeding such persistent active lava lake and the mechanisms controlling the architecture of magma storage remain unclear. Here, we combine high-resolution satellite optical imagery and radar interferometry (InSAR) to infer the shape, location and orientation of the conduits feeding the 2017 Erta Ale eruption. We show that the lava lake was rooted in a vertical dike-shaped reservoir that had been inflating prior to the eruption. The magma was subsequently transferred into a shallower feeder dike. We also find a shallow, horizontal magma lens elongated along axis inflating beneath the volcano during the later period of the eruption. Edifice stress modeling suggests the hydraulically connected system of horizontal and vertical thin magmatic bodies able to open and close are arranged spatially according to stresses induced by loading and unloading due to topographic changes. Our combined approach may provide new constraints on the organization of magma plumbing systems beneath volcanoes in continental and marine settings.

The rise of peptic ulcer, 1900-1950.

Science.gov (United States)

Grob, Gerald N

2003-01-01

The seeming increase in the incidence of peptic ulcer after 1900 quickly occupied the attention of physicians. Their understanding and treatment of peptic ulcer was shaped not only by new diagnostic tools, but by differences between contesting medical specialties, broad concepts or paradigms current in the larger medical and scientific community, and prevailing social and ideological beliefs. Surgeons and internists, for example, were often at odds over appropriate therapies; each maintained that personal experiences demonstrated the efficacy of their therapies. Nor were etiological theories derived from empirical data. The claim that peptic ulcer resulted from focal infections was simply a reflection of the popularity of germ theory. Other explanations included the role of stress, race, constitutional makeup, psychosomatic factors, and the pressures of modern industrial society. Virtually all were derivative and reflected social and intellectual currents that were common in the larger society of which medicine was but a part. Thus, the history of peptic ulcer during the first half of the 20th century provides an instructive and in many ways a typical case study in the complexities posed by the emergence of modern medicine.

Facial ulcerations due to Acinetobacter baumannii: Vessel thrombosis with bacterial mycelia

Directory of Open Access Journals (Sweden)

Dong Ming Li

2014-01-01

Full Text Available A 14-year-old girl presented with a 2-week history of progressive facial ulcerations that did not respond to cephalexin and topical dexamethasone. Biopsy on the ulcer showed rod-shaped bacteria and actinomycetes-like mycelia in the vessel walls and within thrombi. Tissue culture yielded Acinetobacter baumannii, which was resistant to cephalexin. A favourite outcome was achieved with minocycline treatment. This is the first case report of A. baumannii-related vasculitis.

Diabetic foot disease: impact of ulcer location on ulcer healing

DEFF Research Database (Denmark)

Pickwell, KM; Siersma, Volkert Dirk; Kars, M

2013-01-01

Healing of heel ulcers in patients with diabetes is considered to be poor, but there is relatively little information on the influence of ulcer location on ulcer healing.......Healing of heel ulcers in patients with diabetes is considered to be poor, but there is relatively little information on the influence of ulcer location on ulcer healing....

Peptic Ulcers

Science.gov (United States)

... people of any age — even kids — can develop ulcers. About Peptic Ulcers An ulcer is a sore, which means it's ... that most people can be cured. Causes of Peptic Ulcers in Kids Although stress and certain foods may ...

Volcanoes: Nature's Caldrons Challenge Geochemists.

Science.gov (United States)

Zurer, Pamela S.

1984-01-01

Reviews various topics and research studies on the geology of volcanoes. Areas examined include volcanoes and weather, plate margins, origins of magma, magma evolution, United States Geological Survey (USGS) volcano hazards program, USGS volcano observatories, volcanic gases, potassium-argon dating activities, and volcano monitoring strategies.…

Is perforated marginal ulcer after the surgery of gastroduodenal ulcer associated with inadequate treatment for Helicobacter pylori eradication?

Science.gov (United States)

Aydinli, Bulent; Yilmaz, Omer; Ozturk, Gurkan; Yildigan, M Ilhan; Gursan, Nesrin; Basoglu, Mahmut

2007-09-01

A marginal ulcer developing after an initial operation for gastroduodenal ulcer is a serious threat to the patient, and a challenge to surgeons. Helicobacter pylori is the primary cause of peptic ulcer disease. However, its role in ulcer recurrence, especially of marginal ulcer (MU), after peptic ulcer surgery is unclear. This study aimed to determine any association between H. pylori infection and perforated MU by comparing the prevalence of H. pylori and nonsteroidal anti-inflammatory drugs (NSAIDs) use in patients with perforated (PMU) and in those with nonperforated MU (NPMU). The study retrospectively evaluated the records of 16 patients with PMU who underwent surgical treatment and 24 patients with NPMU who underwent medical treatment in Atatürk University, School of Medicine, Department of General Surgery and Gastroenterology, between January 1995 and December 2004. The rate of H. pylori in the PMU group was significantly higher than that of the NPMU group (P PMU compared with NPMU patients (P PMU (P PMU operation especially in cases with impaired hemodynamics, severe peritoneal contamination, and/or a diameter smaller than 1 cm and avoiding the use of NSAIDs will surely reduce the risk of relapsing ulcers.

[ENDOSCOPIC ANATOMY AND MORPHOLOGICAL CHANGES OF THE GASTRODUODENAL JUNCTION IN ULCER OF THE DUODENUM].

Science.gov (United States)

Kolesnikova, E V; Dronova, O B; Kagan, Il; Tretjakov, A A; Kogan, E L

2015-01-01

To Improve the diagnosis of duodenal ulcer and preneoplastic changes of gastroduodenal transition. 112 patients with duodenal ulcer, 208 healthy pearsons of three age periods: second period of mature age, elderly and senile age were examined. Video endoscopy equipment company "OLYMPUS" (Japan), morphological methods and the determination of Helicobacter pylori (Hp) were used. The connecting line of gastric and duodenal mucous membrane can be located on the gastric side of the pylorus (13% in normal cases and 22.3% in cases of ulcer disease), on pylorus and go into the bulbus of duodenum (87% and 77.7 %, respectively), in cases of duodenal ulcer the connecting line more often has jagged and tongue-shaped form. Mucous membrane forms folds in prepyloric part of the stomach most often on the front wall in healthy pearsons in 14.4% of cases, in patients with duodenal ulcer--in 75.9%. The number of folds decreases with age. HP, atrophy, intestinal metaplasia of the mucous membrane is more often found in duodenal ulcer disease--76.8%, 69.7% and 62.5% comparing with healthy persons: 51.4%, 5.3% and 47.7% respectively. Frequency of preneoplastic changes increases with age. The individual differences of the mucous membrane of the gastroduodenal transition are identified. They are expressed in the particular location and shape of the connecting line of gastric and duodenal mucous membranes in normal cases and in cases of ulcer disease in different age groups. Some endoscopic changes requiring biopsy and morphological studies are revealed.

Anti-ulcer Activity.

Science.gov (United States)

2016-01-01

This chapter explains the procedure of ethanol-induced ulcer to check the protective effect of drugs over induced ulcer in rats. Ulcer is defined as the erosion in the lining of the stomach or duodenum and is caused by the disruptions of the gastric mucosal defence and repair systems. Ulceration of stomach is called gastric ulcer and that of duodenum is called duodenal ulcer and together peptic ulcer. In clinical practice, peptic ulcer is one of the most prevalent gastrointestinal disorders, which commonly occurs in developed countries.

Total contact cast for neuropathic diabetic foot ulcers

International Nuclear Information System (INIS)

Ali, R.; Yaqoob, M.Y.

2008-01-01

To determine the outcome of diabetic neuropathic foot ulcers treated with Total Contact Cast (TCC) in terms of percentage of ulcers healed and time to heal. The study included diabetic patients with non-ischemic neuropathic foot ulcers of upto grade 2 of Wagner's classification. Ulcers were debrided off necrotic tissues and Total Contact Cast (TCC) was applied. TCC was renewed every 2 weeks till healing. Cases were labeled as cast failure when there was no reduction in wound size in 4 consecutive weeks or worsening to a higher grade. Main outcome measures were the percentage of ulcers healed and time to heal in the cast. Thirty four (87.17%) patients were males and 5(12.82%) were females. The mean age was 62 +- 13.05 years. All patients had NIDDM. Out of the 52 ulcers, 41(78.84%) healed with TCC in an average 2 casts duration (mean 32 days). There were 11(21.15%) cast failure. Majority (63.63%) of cast failure ulcers were located on pressure bearing area of heel. Most (90%) of the ulcers on forefoot and midsole region healed with TCC (p<0.001). Longer ulcer duration (mean 57.45 +- 29.64 days) significantly reduced ulcer healing (p<0.001). Total contact cast was an effective treatment modality for neuropathic diabetic foot ulcers of Wagner's grade 2, located on forefoot and midsole region. (author)

Helicobacter pylori Eradication within 120 Days Is Associated with Decreased Complicated Recurrent Peptic Ulcers in Peptic Ulcer Bleeding Patients.

Science.gov (United States)

Chang, Shen Shong; Hu, Hsiao-Yun

2015-05-23

The connection between Helicobacter pylori and complicated peptic ulcer disease in peptic ulcer bleeding (PUB) patients taking nonsteroidal anti-inflammatory drugs has not been established. In this study, we sought to determine whether delayed H. pylori eradication therapy in PUB patients increases complicated recurrent peptic ulcers. We identified inpatient PUB patients using the Taiwan National Health Insurance Research Database. We categorized patients into early (time lag ≤120 days after peptic ulcer diagnosis) and late H. pylori eradication therapy groups. The Cox proportional hazards model was used. The primary outcome was rehospitalization for patients with complicated recurrent peptic ulcers. Our data indicated that the late H. pylori eradication therapy group had a higher rate of complicated recurrent peptic ulcers (hazard ratio [HR], 1.52; p=0.006), with time lags of more than 120 days. However, our results indicated a similar risk of complicated recurrent peptic ulcers (HR, 1.20; p=0.275) in time lags of more than 1 year and (HR, 1.10; p=0.621) more than 2 years. H. pylori eradication within 120 days was associated with decreased complicated recurrent peptic ulcers in patients with PUB. We recommend that H. pylori eradication should be conducted within 120 days in patients with PUB.

Pressure ulcers and prevention among acute care hospitals in the United States.

Science.gov (United States)

Bergquist-Beringer, Sandra; Dong, Lei; He, Jianghua; Dunton, Nancy

2013-09-01

Most pressure ulcers can be prevented with evidence-based practice. Many studies describe the implementation of a pressure ulcer prevention program but few report the effect on outcomes across acute care facilities. Data on hospital-acquired pressure ulcers and prevention from the National Database of Nursing Quality Indicators 2010 Pressure Ulcer Surveys were linked to hospital characteristics and nurse staffing measures within the data set. The sample consisted of 1,419 hospitals from across the United States and 710,626 patients who had been surveyed for pressure ulcers in adult critical care, step-down, medical, surgical, and medical/surgical units. Hierarchical logistic regression analysis was performed to identify study variables associated with hospital-acquired pressure ulcers among patients at risk for these ulcers. The rate of hospital-acquired pressure ulcers was 3.6% across all surveyed patients and 7.9% among those at risk. Patients who received a skin and pressure ulcer risk assessment on admission were less likely to develop a pressure ulcer. Additional study variables associated with lower hospital-acquired pressure ulcer rates included a recent reassessment of pressure ulcer risk, higher Braden Scale scores, a recent skin assessment, routine repositioning, and Magnet or Magnet-applicant designation. Variables associated with a higher likelihood of hospital-acquired pressure ulcers included nutritional support, moisture management, larger hospital size, and academic medical center status. Results provide empirical support for pressure ulcer prevention guideline recommendations on skin assessment, pressure ulcer risk assessment, and routine repositioning, but the 7.9% rate of hospital-acquired pressure ulcers among at-risk patients suggests room for improvement in pressure ulcer prevention practice.

Volcanoes: observations and impact

Science.gov (United States)

Thurber, Clifford; Prejean, Stephanie G.

2012-01-01

Volcanoes are critical geologic hazards that challenge our ability to make long-term forecasts of their eruptive behaviors. They also have direct and indirect impacts on human lives and society. As is the case with many geologic phenomena, the time scales over which volcanoes evolve greatly exceed that of a human lifetime. On the other hand, the time scale over which a volcano can move from inactivity to eruption can be rather short: months, weeks, days, and even hours. Thus, scientific study and monitoring of volcanoes is essential to mitigate risk. There are thousands of volcanoes on Earth, and it is impractical to study and implement ground-based monitoring at them all. Fortunately, there are other effective means for volcano monitoring, including increasing capabilities for satellite-based technologies.

Definition and Facts for Peptic Ulcers (Stomach Ulcers)

Science.gov (United States)

... an H. pylori infection never develop a peptic ulcer. Peptic ulcers caused by H. pylori are uncommon in ... saliva or other bodily fluids. 3 Who develops peptic ulcers caused by tumors? People who have Zollinger-Ellison ...

Continuous monitoring of volcanoes with borehole strainmeters

Science.gov (United States)

Linde, Alan T.; Sacks, Selwyn

Monitoring of volcanoes using various physical techniques has the potential to provide important information about the shape, size and location of the underlying magma bodies. Volcanoes erupt when the pressure in a magma chamber some kilometers below the surface overcomes the strength of the intervening rock, resulting in detectable deformations of the surrounding crust. Seismic activity may accompany and precede eruptions and, from the patterns of earthquake locations, inferences may be made about the location of magma and its movement. Ground deformation near volcanoes provides more direct evidence on these, but continuous monitoring of such deformation is necessary for all the important aspects of an eruption to be recorded. Sacks-Evertson borehole strainmeters have recorded strain changes associated with eruptions of Hekla, Iceland and Izu-Oshima, Japan. Those data have made possible well-constrained models of the geometry of the magma reservoirs and of the changes in their geometry during the eruption. The Hekla eruption produced clear changes in strain at the nearest instrument (15 km from the volcano) starting about 30 minutes before the surface breakout. The borehole instrument on Oshima showed an unequivocal increase in the amplitude of the solid earth tides beginning some years before the eruption. Deformational changes, detected by a borehole strainmeter and a very long baseline tiltmeter, and corresponding to the remote triggered seismicity at Long Valley, California in the several days immediately following the Landers earthquake are indicative of pressure changes in the magma body under Long Valley, raising the question of whether such transients are of more general importance in the eruption process. We extrapolate the experience with borehole strainmeters to estimate what could be learned from an installation of a small network of such instruments on Mauna Loa. Since the process of conduit formation from the magma sources in Mauna Loa and other

Tear production and intraocular pressure in canine eyes with corneal ulceration

Directory of Open Access Journals (Sweden)

David L. Williams

2017-05-01

Full Text Available This study aimed to evaluate changes in lacrimation and intraocular pressure (IOP in dogs with unilateral corneal ulceration using the Schirmer tear test (STT and rebound (TonoVet® tonometry. IOP and STT values were recorded in both ulcerated and non-ulcerated (control eyes of 100 dogs diagnosed with unilateral corneal ulceration. Dogs presented with other ocular conditions as their primary complaint were excluded from this study. The mean ± standard deviation for STT values in the ulcerated and control eyes were 20.2±4.6 mm/min and 16.7±3.5 mm/min respectively. The mean ± standard deviation for IOP in the ulcerated and control eyes were 11.9±3.1 mmHg and 16.7±2.6 mmHg respectively. STT values were significantly higher (p<0.000001 in the ulcerated eye compared to the control eye while IOP was significantly lower (p<0.0001. There is an increase in lacrimation and a decrease in IOP in canine eyes with corneal ulceration. The higher tear production in ulcerated eyes shows the importance of measuring STT in both eyes in cases of corneal ulceration, since this increased lacrimation may mask an underlying keratoconjunctivitis sicca only evident in the contralateral eye. The lower IOP in ulcerated eyes is likely to relate to mild uveitic change in the ulcerated eye with a concomitant increase in uveoscleral aqueous drainage. While these changes in tear production and IOP in ulcerated eyes are widely recognised in both human and veterinary ophthalmology, it appears that this is the first controlled documented report of these changes in a large number of individuals.

Volcano ecology: flourishing on the flanks of Mount St. Helens

Science.gov (United States)

Rhonda Mazza; Charlie Crisafulli

2016-01-01

Mount St. Helens’ explosive eruption on May 18, 1980, was a pivotal moment in the field of disturbance ecology. The subsequent sustained, integrated research effort has shaped the development of volcano ecology, an emerging field of focused research. Excessive heat, burial, and impact force are some of the disturbance mechanisms following an eruption. They are also...

A Scientific Excursion: Volcanoes.

Science.gov (United States)

Olds, Henry, Jr.

1983-01-01

Reviews an educationally valuable and reasonably well-designed simulation of volcanic activity in an imaginary land. VOLCANOES creates an excellent context for learning information about volcanoes and for developing skills and practicing methods needed to study behavior of volcanoes. (Author/JN)

Serum ferritin in recurrent oral ulceration

International Nuclear Information System (INIS)

Challacombe, S.J.; Scully, C.; Keevil, B.; Lehner, T.

1983-01-01

A sensitive radio-assay for ferritin was developed and used to examine serum ferritin levels in 105 patients with recurrent oral ulceration (ROU), 41 patients with Behcet's syndrome (BS), 42 with other ulcerative oral lesions, 35 patients with non-ulcerative oral lesions and in 78 controls. Ferritin levels increased with age and were significantly higher in males than females. The mean ferritin concentrations in male patients with ROU, BS or with other oral ulcers were significantly reduced in comparison with controls, and in female patients were significantly reduced in those with major aphthous ulcers. The prevalence of low serum ferritin levels was about 8% in patients with ROU, 15% in BS and 9.5% in patients with other ulcerative oral lesions, compared with less than 3% in patients with non-ulcerative oral disorders and in controls. Most of the iron-deficient patients were female. Serum ferritin levels did not directly correlate with serum iron levels and may be a more accurate indicator of iron deficiency. Furthermore, serum ferritin can distinguish between patients with true iron deficiency and those with secondary sideropenia. It is suggested that in a small number of patients, oral ulceration may be a presenting sign of iron deficiency, and that in a further small proportion of patients, ROU already present will be exacerbated by concurrent iron deficiency. Both groups will show a therapeutic response to correction of the iron deficiency. The results suggest that serum ferritin levels are a useful part of the haematological investigatons in patients with ROU. (author)

Compression stockings for treating venous leg ulcers: measurement of interface pressure under a new ulcer kit.

Science.gov (United States)

Partsch, B; Partsch, H

2008-01-01

The aim of this study was to measure the interface pressure of a newly designed two-layer compression stocking (Mediven ulcer kit Medi QMBH, Bayreuth, Germany) in different body positions and to compare the values with those obtained with another two-layer product. Interface pressure was measured on the distal medial leg in 16 legs of volunteers, with the basic layer alone and with the whole stocking kit in the supine, sitting and standing position for both stocking systems. The literature concerning ulcer-healing rates is reviewed. Mediven ulcerkit produced statistically significant higher pressure values than the ulcer stocking with a median resting value of 35.5 mmHg in the supine and 42.5 mmHg in the standing position. The pressure while standing comes close to values exerted by bandages. The basic layer alone applies a pressure of 20.5 mmHg. Especially designed compression stockings exerting sufficient interface pressure may be indicated in patients with small ulcers of short duration.

Prevention of recurrent foot ulcers with plantar pressure-based in-shoe orthoses: the CareFUL prevention multicenter randomized controlled trial.

Science.gov (United States)

Ulbrecht, Jan S; Hurley, Timothy; Mauger, David T; Cavanagh, Peter R

2014-07-01

To assess the efficacy of in-shoe orthoses that were designed based on shape and barefoot plantar pressure in reducing the incidence of submetatarsal head plantar ulcers in people with diabetes, peripheral neuropathy, and a history of similar prior ulceration. Single-blinded multicenter randomized controlled trial with subjects randomized to wear shape- and pressure-based orthoses (experimental, n = 66) or standard-of-care A5513 orthoses (control, n = 64). Patients were followed for 15 months, until a study end point (forefoot plantar ulcer or nonulcerative plantar forefoot lesion) or to study termination. Proportional hazards regression was used for analysis. There was a trend in the composite primary end point (both ulcers and nonulcerative lesions) across the full follow-up period (P = 0.13) in favor of the experimental orthoses. This trend was due to a marked difference in ulcer occurrence (P = 0.007) but no difference in the rate of nonulcerative lesions (P = 0.76). At 180 days, the ulcer prevention effect of the experimental orthoses was already significant (P = 0.003) when compared with control, and the benefit of the experimental orthoses with respect to the composite end point was also significant (P = 0.042). The hazard ratio was 3.4 (95% CI 1.3-8.7) for the occurrence of a submetatarsal head plantar ulcer in the control compared with experimental arm over the duration of the study. We conclude that shape- and barefoot plantar pressure-based orthoses were more effective in reducing submetatarsal head plantar ulcer recurrence than current standard-of-care orthoses, but they did not significantly reduce nonulcerative lesions. © 2014 by the American Diabetes Association.

Prevention of Recurrent Foot Ulcers With Plantar Pressure–Based In-Shoe Orthoses: The CareFUL Prevention Multicenter Randomized Controlled Trial

Science.gov (United States)

Ulbrecht, Jan S.; Hurley, Timothy; Mauger, David T.

2014-01-01

OBJECTIVE To assess the efficacy of in-shoe orthoses that were designed based on shape and barefoot plantar pressure in reducing the incidence of submetatarsal head plantar ulcers in people with diabetes, peripheral neuropathy, and a history of similar prior ulceration. RESEARCH DESIGN AND METHODS Single-blinded multicenter randomized controlled trial with subjects randomized to wear shape- and pressure-based orthoses (experimental, n = 66) or standard-of-care A5513 orthoses (control, n = 64). Patients were followed for 15 months, until a study end point (forefoot plantar ulcer or nonulcerative plantar forefoot lesion) or to study termination. Proportional hazards regression was used for analysis. RESULTS There was a trend in the composite primary end point (both ulcers and nonulcerative lesions) across the full follow-up period (P = 0.13) in favor of the experimental orthoses. This trend was due to a marked difference in ulcer occurrence (P = 0.007) but no difference in the rate of nonulcerative lesions (P = 0.76). At 180 days, the ulcer prevention effect of the experimental orthoses was already significant (P = 0.003) when compared with control, and the benefit of the experimental orthoses with respect to the composite end point was also significant (P = 0.042). The hazard ratio was 3.4 (95% CI 1.3–8.7) for the occurrence of a submetatarsal head plantar ulcer in the control compared with experimental arm over the duration of the study. CONCLUSIONS We conclude that shape- and barefoot plantar pressure–based orthoses were more effective in reducing submetatarsal head plantar ulcer recurrence than current standard-of-care orthoses, but they did not significantly reduce nonulcerative lesions. PMID:24760263

Darwin's triggering mechanism of volcano eruptions

Science.gov (United States)

Galiev, Shamil

2010-05-01

Charles Darwin wrote that ‘… the elevation of many hundred square miles of territory near Concepcion is part of the same phenomenon, with that splashing up, if I may so call it, of volcanic matter through the orifices in the Cordillera at the moment of the shock;…' and ‘…a power, I may remark, which acts in paroxysmal upheavals like that of Concepcion, and in great volcanic eruptions,…'. Darwin reports that ‘…several of the great chimneys in the Cordillera of central Chile commenced a fresh period of activity ….' In particular, Darwin reported on four-simultaneous large eruptions from the following volcanoes: Robinson Crusoe, Minchinmavida, Cerro Yanteles and Peteroa (we cite the Darwin's sentences following his The Voyage of the Beagle and researchspace. auckland. ac. nz/handle/2292/4474). Let us consider these eruptions taking into account the volcano shape and the conduit. Three of the volcanoes (Minchinmavida (2404 m), Cerro Yanteles (2050 m), and Peteroa (3603 m)) are stratovolcanos and are formed of symmetrical cones with steep sides. Robinson Crusoe (922 m) is a shield volcano and is formed of a cone with gently sloping sides. They are not very active. We may surmise, that their vents had a sealing plug (vent fill) in 1835. All these volcanoes are conical. These common features are important for Darwin's triggering model, which is discussed below. The vent fill material, usually, has high level of porosity and a very low tensile strength and can easily be fragmented by tension waves. The action of a severe earthquake on the volcano base may be compared with a nuclear blast explosion of the base. It is known, that after a underground nuclear explosion the vertical motion and the surface fractures in a tope of mountains were observed. The same is related to the propagation of waves in conical elements. After the explosive load of the base. the tip may break and fly off at high velocity. Analogous phenomenon may be generated as a result of a

Recent Seismicity in the Ceboruco Volcano, Western Mexico

Science.gov (United States)

Nunez, D.; Chávez-Méndez, M. I.; Nuñez-Cornu, F. J.; Sandoval, J. M.; Rodriguez-Ayala, N. A.; Trejo-Gomez, E.

2017-12-01

The Ceboruco volcano is the largest (2280 m.a.s.l) of several volcanoes along the Tepic-Zacoalco rift zone in Nayarit state (Mexico). During the last 1000 years, this volcano had effusive-explosive episodes with eight eruptions providing an average of one eruption each 125 years. Since the last eruption occurred in 1870, 147 years ago, a new eruption likelihood is really high and dangerous due to nearby population centers, important roads and lifelines that traverse the volcano's slopes. This hazards indicates the importance of monitoring the seismicity associated with the Ceboruco volcano whose ongoing activity is evidenced by fumaroles and earthquakes. During 2003 and 2008, this region was registered by just one Lennartz Marslite seismograph featuring a Lennartz Le3D sensor (1 Hz) [Rodríguez Uribe et al. (2013)] where they observed that seismicity rates and stresses appear to be increasing indicating higher levels of activity within the volcano. Until July 2017, a semi-permanent network with three Taurus (Nanometrics) and one Q330 Quanterra (Kinemetrics) digitizers with Lennartz 3Dlite sensors of 1 Hz natural frequency was registering in the area. In this study, we present the most recent seismicity obtained by the semi-permanent network and a temporary network of 21 Obsidians 4X and 8X (Kinemetrics) covering an area of 16 km x 16 km with one station every 2.5-3 km recording from November 2016 to July 2017.

Cook Inlet and Kenai Peninsula, Alaska ESI: VOLCANOS (Volcano Points)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains the locations of volcanos in Cook Inlet and Kenai Peninsula, Alaska. Vector points in the data set represent the location of the volcanos....

Digital Geologic Map Database of Medicine Lake Volcano, Northern California

Science.gov (United States)

Ramsey, D. W.; Donnelly-Nolan, J. M.; Felger, T. J.

2010-12-01

Medicine Lake volcano, located in the southern Cascades ~55 km east-northeast of Mount Shasta, is a large rear-arc, shield-shaped volcano with an eruptive history spanning nearly 500 k.y. Geologic mapping of Medicine Lake volcano has been digitally compiled as a spatial database in ArcGIS. Within the database, coverage feature classes have been created representing geologic lines (contacts, faults, lava tubes, etc.), geologic unit polygons, and volcanic vent location points. The database can be queried to determine the spatial distributions of different rock types, geologic units, and other geologic and geomorphic features. These data, in turn, can be used to better understand the evolution, growth, and potential hazards of this large, rear-arc Cascades volcano. Queries of the database reveal that the total area covered by lavas of Medicine Lake volcano, which range in composition from basalt through rhyolite, is about 2,200 km2, encompassing all or parts of 27 U.S. Geological Survey 1:24,000-scale topographic quadrangles. The maximum extent of these lavas is about 80 km north-south by 45 km east-west. Occupying the center of Medicine Lake volcano is a 7 km by 12 km summit caldera in which nestles its namesake, Medicine Lake. The flanks of the volcano, which are dotted with cinder cones, slope gently upward to the caldera rim, which reaches an elevation of nearly 2,440 m. Approximately 250 geologic units have been mapped, only half a dozen of which are thin surficial units such as alluvium. These volcanic units mostly represent eruptive events, each commonly including a vent (dome, cinder cone, spatter cone, etc.) and its associated lava flow. Some cinder cones have not been matched to lava flows, as the corresponding flows are probably buried, and some flows cannot be correlated with vents. The largest individual units on the map are all basaltic in composition, including the late Pleistocene basalt of Yellowjacket Butte (296 km2 exposed), the largest unit on the

Pressure Ulcer Prevention

Science.gov (United States)

2009-01-01

compared with soap and water to reduce the incidence of grade 1 or 2 pressure ulcers in persons with urinary and fecal incontinence. Conclusions There is moderate quality evidence that an alternative foam mattress is effective in preventing the development of pressure ulcers compared with a standard hospital foam mattress. However, overall there remains a paucity of moderate or higher quality evidence in the literature to support many of the preventive interventions. Until better quality evidence is available, pressure ulcer preventive care must be guided by expert opinion for those interventions where low or very low quality evidence supports the effectiveness of such interventions. Abbreviations CI Confidence interval GRADE Grading of Recommendation Assessment, Development, and Evaluation ICU Intensive care unit MAS Medical Advisory Secretariat NPUAP National Pressure Ulcer Advisory Panel RAS Risk assessment scale RCT Randomized controlled trial RNAO Registered Nurses Association of Ontario RR Relative risk RRR Relative risk reduction PMID:23074524

A Versatile Time-Lapse Camera System Developed by the Hawaiian Volcano Observatory for Use at Kilauea Volcano, Hawaii

Science.gov (United States)

Orr, Tim R.; Hoblitt, Richard P.

2008-01-01

Volcanoes can be difficult to study up close. Because it may be days, weeks, or even years between important events, direct observation is often impractical. In addition, volcanoes are often inaccessible due to their remote location and (or) harsh environmental conditions. An eruption adds another level of complexity to what already may be a difficult and dangerous situation. For these reasons, scientists at the U.S. Geological Survey (USGS) Hawaiian Volcano Observatory (HVO) have, for years, built camera systems to act as surrogate eyes. With the recent advances in digital-camera technology, these eyes are rapidly improving. One type of photographic monitoring involves the use of near-real-time network-enabled cameras installed at permanent sites (Hoblitt and others, in press). Time-lapse camera-systems, on the other hand, provide an inexpensive, easily transportable monitoring option that offers more versatility in site location. While time-lapse systems lack near-real-time capability, they provide higher image resolution and can be rapidly deployed in areas where the use of sophisticated telemetry required by the networked cameras systems is not practical. This report describes the latest generation (as of 2008) time-lapse camera system used by HVO for photograph acquisition in remote and hazardous sites on Kilauea Volcano.

Perforated peptic ulcer and short-term mortality among tramadol users.

Science.gov (United States)

Tørring, Marie L; Riis, Anders; Christensen, Steffen; Thomsen, Reimar W; Jepsen, Peter; Søndergaard, Jens; Sørensen, Henrik T

2008-04-01

28.7% overall and 48.4% among users of tramadol alone. Compared with the 645 patients who used neither tramadol nor NSAIDs, the adjusted mortality rate in the 30 days following hospitalization was 2.02-fold [95% confidence interval (CI) 1.17, 3.48] higher for the 31 'tramadol only' users, 1.41-fold (95% CI 1.12, 1.78) higher for the 495 NSAID users and 1.32-fold (95% CI 0.89, 1.95) higher for the 100 patients who used both drugs. Among patients hospitalized for perforated peptic ulcer, tramadol appears to increase mortality at a level comparable to NSAIDs.

Ugh! Ulcers

Science.gov (United States)

... believed that ulcers were caused by stress and spicy foods. Then, in 1982, two doctors (Barry Marshall and ... not develop ulcers. Doctors still aren't sure why, but they think that part ... of pain relievers , like aspirin or ibuprofen, can cause ulcers in some ...

The Impacts of Peptic Ulcer on Stroke Recurrence.

Science.gov (United States)

Xu, Zongliang; Wang, Ling; Lin, Ying; Wang, Zhaojun; Zhang, Yun; Li, Junrong; Li, Shenghua; Ye, Zusen; Yuan, Kunxiong; Shan, Wanying; Liu, Xinfeng; Fan, Xinying; Xu, Gelin

2018-04-10

Peptic ulcer has been associated with an increased risk of stroke. This study aimed to evaluate the impacts of peptic ulcer on stroke recurrence and mortality. Patients with first-ever ischemic stroke were retrospectively confirmed with or without a history of peptic ulcer. The primary end point was defined as fatal and nonfatal stroke recurrence. Risks of 1-year fatal and nonfatal stroke recurrence were analyzed with the Kaplan-Meier method. Predictors of fatal and nonfatal stroke recurrence were evaluated with the Cox proportional hazards model. Among the 2577 enrolled patients with ischemic stroke, 129 (5.0%) had a history of peptic ulcer. The fatal and nonfatal stroke recurrence within 1 year of the index stroke was higher in patients with peptic ulcer than in patients without peptic ulcer (12.4% versus 7.2%, P = .030). Cox proportional hazards model detected that age (hazard ratio [HR] = 1.018, 95% confidence interval [CI] 1.005-1.031, P = .008), hypertension (HR = 1.397, 95% CI 1.017-1.918, P = .039), and history of peptic ulcer (HR = 1.853, 95% CI 1.111-3.091, P = .018) were associated with stroke recurrence. Ischemic stroke patients with peptic ulcer may have an increased risk of stroke recurrence. The results emphasize the importance of appropriate prevention and management of peptic ulcer for secondary stroke prevention. Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.

Recurrent peptic ulcers in patients following successful Helicobacter pylori eradication: a multicenter study of 4940 patients.

Science.gov (United States)

Miwa, Hiroto; Sakaki, Nobuhiro; Sugano, Kentaro; Sekine, Hitoshi; Higuchi, Kazuhide; Uemura, Naomi; Kato, Mototsugu; Murakami, Kazunari; Kato, Chieko; Shiotani, Akiko; Ohkusa, Toshifumi; Takagi, Atsushi; Aoyama, Nobuo; Haruma, Ken; Okazaki, Kazuichi; Kusugami, Kazuo; Suzuki, Masayuki; Joh, Takashi; Azuma, Takeshi; Yanaka, Akinori; Suzuki, Hidekazu; Hashimoto, Hiroshi; Kawai, Takashi; Sugiyama, Toshiro

2004-02-01

Although curative treatment of Helicobacter pylori infection markedly reduces the relapse of peptic ulcers, the details of the ulcers that do recur is not well characterized. The aim of this study is to describe the recurrence rate and specific features of peptic ulcers after cure of H. pylori infection. This was a multicenter study involving 4940 peptic ulcer patients who were H. pylori negative after successful eradication treatment and were followed for up to 48 months. The annual incidence of ulcer relapse in H. pylori-cured patients, background of patients with relapsed ulcers, time to relapse, ulcer size, and site of relapsed ulcers were investigated. Crude peptic ulcer recurrence rate was 3.02% (149/4940). The annual recurrence rates of gastric, duodenal and gastroduodenal ulcer were 2.3%, 1.6%, and 1.6%, respectively. Exclusion of patients who took NSAIDs led annual recurrence rates to 1.9%, 1.5% and 1.3%, respectively. The recurrence rate was significantly higher in gastric ulcer. Recurrence rates of patients who smoked, consumed alcohol, and used NSAIDs were significantly higher in those with gastric ulcer recurrence compared to duodenal ulcer recurrence (e.g. 125 of 149 [83.9%] relapsed ulcers recurred at the same or adjacent sites as the previous ulcers). Curative treatment of H. pylori infection is useful in preventing ulcer recurrence. Gastric ulcer is more likely to relapse than duodenal ulcer. Recurrent ulcer tended to recur at the site of the original ulcers.

Non-contact ulcer area calculation system for neuropathic foot ulcer.

Science.gov (United States)

Shah, Parth; Mahajan, Siddaram; Nageswaran, Sharmila; Paul, Sathish Kumar; Ebenzer, Mannam

2017-08-11

Around 125,785 new cases in year 2013-14 of leprosy were detected in India as per WHO report on leprosy in September 2015 which accounts to approximately 62% of the total new cases. Anaesthetic foot caused by leprosy leads to uneven loading of foot leading to ulcer in approximately 20% of the cases. Much efforts have gone in identifying newer techniques to efficiently monitor the progress of ulcer healing. Current techniques followed in measuring the size of ulcers, have not been found to be so accurate but are still is followed by clinicians across the globe. Quantification of prognosis of the condition would be required to understand the efficacy of current treatment methods and plan for further treatment. This study aims at developing a non contact technique to precisely measure the size of ulcer in patients affected by leprosy. Using MATLAB software, GUI was designed to process the acquired ulcer image by segmenting and calculating the pixel area of the image. The image was further converted to a standard measurement using a reference object. The developed technique was tested on 16 ulcer images acquired from 10 leprosy patients with plantar ulcers. Statistical analysis was done using MedCalc analysis software to find the reliability of the system. The analysis showed a very high correlation coefficient (r=0.9882) between the ulcer area measurements done using traditional technique and the newly developed technique, The reliability of the newly developed technique was significant with a significance level of 99.9%. The designed non-contact ulcer area calculating system using MATLAB is found to be a reliable system in calculating the size of ulcers. The technique would help clinicians have a reliable tool to monitor the progress of ulcer healing and help modify the treatment protocol if needed. Copyright © 2017 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

Diabetic foot ulcer incidence in relation to plantar pressure magnitude and measurement location.

Science.gov (United States)

Ledoux, William R; Shofer, Jane B; Cowley, Matthew S; Ahroni, Jessie H; Cohen, Victoria; Boyko, Edward J

2013-01-01

We prospectively examined the relationship between site-specific peak plantar pressure (PPP) and ulcer risk. Researchers have previously reported associations between diabetic foot ulcer and elevated plantar foot pressure, but the effect of location-specific pressures has not been studied. Diabetic subjects (n=591) were enrolled from a single VA hospital. Five measurements of in-shoe plantar pressure were collected using F-Scan. Pressures were measured at 8 areas: heel, lateral midfoot, medial midfoot, first metatarsal, second through fourth metatarsal, fifth metatarsal, hallux, and other toes. The relationship between incident plantar foot ulcer and PPP or pressure-time integral (PTI) was assessed using Cox regression. During follow-up (2.4years), 47 subjects developed plantar ulcers (10 heel, 12 metatarsal, 19 hallux, 6 other). Overall mean PPP was higher for ulcer subjects (219 vs. 194kPa), but the relationship differed by site (the metatarsals with ulcers had higher pressure, while the opposite was true for the hallux and heel). A statistical analysis was not performed on the means, but hazard ratios from a Cox survival analysis were nonsignificant for PPP across all sites and when adjusted for location. However, when the metatarsals were considered separately, higher baseline PPP was significantly associated with greater ulcer risk; at other sites, this relationship was nonsignificant. Hazard ratios for all PTI data were nonsignificant. Location must be considered when assessing the relationship between PPP and plantar ulceration. © 2013.

Hawaii's volcanoes revealed

Science.gov (United States)

Eakins, Barry W.; Robinson, Joel E.; Kanamatsu, Toshiya; Naka, Jiro; Smith, John R.; Takahashi, Eiichi; Clague, David A.

2003-01-01

Hawaiian volcanoes typically evolve in four stages as volcanism waxes and wanes: (1) early alkalic, when volcanism originates on the deep sea floor; (2) shield, when roughly 95 percent of a volcano's volume is emplaced; (3) post-shield alkalic, when small-volume eruptions build scattered cones that thinly cap the shield-stage lavas; and (4) rejuvenated, when lavas of distinct chemistry erupt following a lengthy period of erosion and volcanic quiescence. During the early alkalic and shield stages, two or more elongate rift zones may develop as flanks of the volcano separate. Mantle-derived magma rises through a vertical conduit and is temporarily stored in a shallow summit reservoir from which magma may erupt within the summit region or be injected laterally into the rift zones. The ongoing activity at Kilauea's Pu?u ?O?o cone that began in January 1983 is one such rift-zone eruption. The rift zones commonly extend deep underwater, producing submarine eruptions of bulbous pillow lava. Once a volcano has grown above sea level, subaerial eruptions produce lava flows of jagged, clinkery ?a?a or smooth, ropy pahoehoe. If the flows reach the ocean they are rapidly quenched by seawater and shatter, producing a steep blanket of unstable volcanic sediment that mantles the upper submarine slopes. Above sea level then, the volcanoes develop the classic shield profile of gentle lava-flow slopes, whereas below sea level slopes are substantially steeper. While the volcanoes grow rapidly during the shield stage, they may also collapse catastrophically, generating giant landslides and tsunami, or fail more gradually, forming slumps. Deformation and seismicity along Kilauea's south flank indicate that slumping is occurring there today. Loading of the underlying Pacific Plate by the growing volcanic edifices causes subsidence, forming deep basins at the base of the volcanoes. Once volcanism wanes and lava flows no longer reach the ocean, the volcano continues to submerge, while

Linking space observations to volcano observatories in Latin America: Results from the CEOS DRM Volcano Pilot

Science.gov (United States)

Delgado, F.; Pritchard, M. E.; Biggs, J.; Arnold, D. W. D.; Poland, M. P.; Ebmeier, S. K.; Wauthier, C.; Wnuk, K.; Parker, A. L.; Amelug, F.; Sansosti, E.; Mothes, P. A.; Macedo, O.; Lara, L.; Zoffoli, S.; Aguilar, V.

2015-12-01

Within Latin American, about 315 volcanoes that have been active in the Holocene, but according to the United Nations Global Assessment of Risk 2015 report (GAR15) 202 of these volcanoes have no seismic, deformation or gas monitoring. Following the 2012 Santorini Report on satellite Earth Observation and Geohazards, the Committee on Earth Observation Satellites (CEOS) has developed a 3-year pilot project to demonstrate how satellite observations can be used to monitor large numbers of volcanoes cost-effectively, particularly in areas with scarce instrumentation and/or difficult access. The pilot aims to improve disaster risk management (DRM) by working directly with the volcano observatories that are governmentally responsible for volcano monitoring, and the project is possible thanks to data provided at no cost by international space agencies (ESA, CSA, ASI, DLR, JAXA, NASA, CNES). Here we highlight several examples of how satellite observations have been used by volcano observatories during the last 18 months to monitor volcanoes and respond to crises -- for example the 2013-2014 unrest episode at Cerro Negro/Chiles (Ecuador-Colombia border); the 2015 eruptions of Villarrica and Calbuco volcanoes, Chile; the 2013-present unrest and eruptions at Sabancaya and Ubinas volcanoes, Peru; the 2015 unrest at Guallatiri volcano, Chile; and the 2012-present rapid uplift at Cordon Caulle, Chile. Our primary tool is measurements of ground deformation made by Interferometric Synthetic Aperture Radar (InSAR) but thermal and outgassing data have been used in a few cases. InSAR data have helped to determine the alert level at these volcanoes, served as an independent check on ground sensors, guided the deployment of ground instruments, and aided situational awareness. We will describe several lessons learned about the type of data products and information that are most needed by the volcano observatories in different countries.

Examination of the accuracy of coding hospital-acquired pressure ulcer stages.

Science.gov (United States)

Coomer, Nicole M; McCall, Nancy T

2013-01-01

Pressure ulcers (PU) are considered harmful conditions that are reasonably prevented if accepted standards of care are followed. They became subject to the payment adjustment for hospitalacquired conditions (HACs) beginning October 1, 2008. We examined several aspects of the accuracy of coding for pressure ulcers under the Medicare Hospital-Acquired Condition Present on Admission (HAC-POA) Program. We used the "4010" claim format as a basis of reference to show some of the issues of the old format, such as the underreporting of pressure ulcer stages on pressure ulcer claims and how the underreporting varied by hospital characteristics. We then used the rate of Stage III and IV pressure ulcer HACs reported in the Hospital Cost and Utilization Project State Inpatient Databases data to look at the sensitivity of PU HAC-POA coding to the number of diagnosis fields. We examined Medicare claims data for FYs 2009 and 2010 to examine the degree that the presence of stage codes were underreported on pressure ulcer claims. We selected all claims with a secondary diagnosis code of pressure ulcer site (ICD-9 diagnosis codes 707.00-707.09) that were not reported as POA (POA of "N" or "U"). We then created a binary indicator for the presence of any pressure ulcer stage diagnosis code. We examine the percentage of claims with a diagnosis of a pressure ulcer site code with no accompanying pressure ulcer stage code. Our results point to underreporting of PU stages under the "4010" format and that the reporting of stage codes varied across hospital type and location. Further, our results indicate that under the "5010" format, a higher number of pressure ulcer HACs can be expected to be reported and we should expect to encounter a larger percentage of pressure ulcers incorrectly coded as POA under the new format. The combination of the capture of 25 diagnosis codes under the new "5010" format and the change from ICD-9 to ICD-10 will likely alleviate the observed underreporting of

The turn team: a novel strategy for reducing pressure ulcers in the surgical intensive care unit.

Science.gov (United States)

Still, Mary D; Cross, Linda C; Dunlap, Martha; Rencher, Rugenia; Larkins, Elizabeth R; Carpenter, David L; Buchman, Timothy G; Coopersmith, Craig M

2013-03-01

Pressure ulcers cause significant morbidity and mortality in the surgical intensive care unit (SICU). The purpose of this study was to determine if a dedicated team tasked with turning and repositioning all hemodynamically stable SICU patients could decrease the formation of pressure ulcers. A total of 507 patients in a 20-bed SICU in a university hospital were assessed for pressure ulcers using a point prevalence strategy, between December 2008 and September 2010, before and after implementation of a team tasked with turning and repositioning all hemodynamically stable patients every 2 hours around the clock. At baseline, when frequent turning was encouraged but not required, a total of 42 pressure ulcers were identified in 278 patients. After implementation of the turn team, a total of 12 pressure ulcers were identified in 229 patients (p < 0.0001). The preintervention group included 34 stage I and II ulcers and 8 higher stage ulcers. After implementation of the turn team, there were 7 stage I and II ulcers and 5 higher stage ulcers. The average Braden score was 16.5 in the preintervention group and 13.4 in the postintervention group (p = 0.04), suggesting that pressure ulcers were occurring in higher risk patients after implementation of the turn team. A team dedicated to turning SICU patients every 2 hours dramatically decreased the incidence of pressure ulcers. The majority of stage I and stage II ulcers appear to be preventable with an aggressive intervention aimed at pressure ulcer prevention. Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Temporal comorbidity of mental disorder and ulcerative colitis.

Science.gov (United States)

Cawthorpe, David; Davidson, Marta

2015-01-01

Ulcerative colitis is an inflammatory bowel disease that rarely exists in isolation in affected patients. We examined the association of ulcerative colitis and International Classification of Diseases mental disorder, as well as the temporal comorbidity of three broad International Classification of Diseases groupings of mental disorders in patients with ulcerative colitis to determine if mental disorder is more likely to occur before or after ulcerative colitis. We used physician diagnoses from the regional health zone of Calgary, Alberta, for patient visits from fiscal years 1994 to 2009 for treatment of any presenting concern in that Calgary health zone (763,449 patients) to identify 5113 patients age younger than 1 year to age 92 years (2120 males, average age = 47 years; 2993 females, average age = 48 years) with a diagnosis of ulcerative colitis. The 16-year cumulative prevalence of ulcerative colitis was 0.0058%, or 58 cases per 10,000 persons (95% confidence interval = 56-60 per 10,000). Although the cumulative prevalence of mental disorder in the overall sample was 5390 per 10,000 (53.9%), we found that 4192 patients with ulcerative colitis (82%) also had a diagnosis of a mental disorder. By annual rate of ulcerative colitis, patients with mental disorder had a significantly higher annual prevalence. The mental disorder grouping neuroses/depressive disorders was most likely to arise before ulcerative colitis (odds ratio = 1.87 for males; 2.24 for females). A temporal association was observed between specific groups of International Classification of Diseases mental disorder and ulcerative colitis, indicating a possible etiologic relationship between the disorders or their treatments, or both.

A model of diffuse degassing at three subduction-related volcanoes

Science.gov (United States)

Williams-Jones, Glyn; Stix, John; Heiligmann, Martin; Charland, Anne; Sherwood Lollar, Barbara; Arner, N.; Garzón, Gustavo V.; Barquero, Jorge; Fernandez, Erik

Radon, CO2 and δ13C in soil gas were measured at three active subduction-related stratovolcanoes (Arenal and Poás, Costa Rica; Galeras, Colombia). In general, Rn, CO2 and δ13C values are higher on the lower flanks of the volcanoes, except near fumaroles in the active craters. The upper flanks of these volcanoes have low Rn concentrations and light δ13C values. These observations suggest that diffuse degassing of magmatic gas on the upper flanks of these volcanoes is negligible and that more magmatic degassing occurs on the lower flanks where major faults and greater fracturing in the older lavas can channel magmatic gases to the surface. These results are in contrast to findings for Mount Etna where a broad halo of magmatic CO2 has been postulated to exist over much of the edifice. Differences in radon levels among the three volcanoes studied here may result from differences in age, the degree of fracturing and faulting, regional structures or the level of hydrothermal activity. Volcanoes, such as those studied here, act as plugs in the continental crust, focusing magmatic degassing towards crater fumaroles, faults and the fractured lower flanks.

Hybrid equation/agent-based model of ischemia-induced hyperemia and pressure ulcer formation predicts greater propensity to ulcerate in subjects with spinal cord injury.

Directory of Open Access Journals (Sweden)

Alexey Solovyev

Full Text Available Pressure ulcers are costly and life-threatening complications for people with spinal cord injury (SCI. People with SCI also exhibit differential blood flow properties in non-ulcerated skin. We hypothesized that a computer simulation of the pressure ulcer formation process, informed by data regarding skin blood flow and reactive hyperemia in response to pressure, could provide insights into the pathogenesis and effective treatment of post-SCI pressure ulcers. Agent-Based Models (ABM are useful in settings such as pressure ulcers, in which spatial realism is important. Ordinary Differential Equation-based (ODE models are useful when modeling physiological phenomena such as reactive hyperemia. Accordingly, we constructed a hybrid model that combines ODEs related to blood flow along with an ABM of skin injury, inflammation, and ulcer formation. The relationship between pressure and the course of ulcer formation, as well as several other important characteristic patterns of pressure ulcer formation, was demonstrated in this model. The ODE portion of this model was calibrated to data related to blood flow following experimental pressure responses in non-injured human subjects or to data from people with SCI. This model predicted a higher propensity to form ulcers in response to pressure in people with SCI vs. non-injured control subjects, and thus may serve as novel diagnostic platform for post-SCI ulcer formation.

Pressure ulcer prevention in patients with advanced illness.

Science.gov (United States)

White-Chu, E Foy; Reddy, Madhuri

2013-03-01

Pressure ulcers can be challenging to prevent, particularly in patients with advanced illnesses. This review summarizes the relevant literature since 2011. Through a MEDLINE and CINAHL database search from January 1, 2011 to June 1, 2012, a total of 14 abstracts were found addressing the prevention of pressure ulcers in persons with advanced illness. Search terms included pressure ulcer, prevention, and control. Advanced illness was defined as patients transitioning from curative to supportive and palliative care. Ten original studies and four review articles specifically addressed pressure ulcer prevention. There were four articles that specifically addressed patients with advanced illness. The studies varied in quality. One systematic review, one randomized controlled trial, three prospective trials, two retrospective trials, one cost-effectiveness analysis, one quality improvement project, one comparative descriptive design, and four review articles were found. The interventions for pressure ulcer prevention were risk assessment, repositioning, surface selection, nutritional support and maintenance of skin integrity with or without incontinence. The quality of pressure ulcer prevention studies in persons with advanced illness is poor. Increased number and higher quality studies are needed to further investigate this important topic for these fragile patients.

Diagnostic value of determination of serum pepsinogen and gastrin levels in patients with peptic ulcer

International Nuclear Information System (INIS)

Xiao Zhansen; Li Jingrong; Feng Jiandong; Wang Yuqiong; Fu Xiufeng; Zhang Lanfeng

2005-01-01

Objective: To investigate the clinical significance of changes of serum pepsinogen and gastrin levels in patients with gastric/duodenal ulcer. Methods: Serum pepsinogen I (PG I), pepsinogen II (PGII), gastrin levels and PG I/PG II ratio were determined with RIA in 100 controls, 61 patients with duodenal ulcer, 46 patients with gastric ulcer, 66 patients with gastric cancer and 101 patients with chronic gastritis. Results: In patients with peptic ulcer (gastric/duodenal), the serum levels of PG I, PG II and PG I/PG II ratio were significantly higher than those in controls (P<0.001); the serum gastrin levels were also significantly higher than those in controls and patients with chronic gastritis (P<0.001), but lower than those in patients with gastric cancer (P<0.001). Among patients with peptic ulcer, the serum PG I level and PG I/PG II ratio were significantly higher in patients with duodenal ulcer than those in patients with gastric ulcer (P<0.001). Conclusion: Excessive high serum levels of PG I, PG II, gastrin and PG I/PG II ratio were some of the high risk factors for peptic ulcer. Those were useful serum markers for diagnosis and follow-up of the disease. (authors)

An analysis of processes that can shape higher education research ...

African Journals Online (AJOL)

This article is not only about African postgraduates at University of Natal: it is also an attempt to delineate what shapes research into Higher Education done under differing conditions and for different purposes (part 1). As material to illustrate this research metamorphosis, the material from an investigation into postgraduates ...

Effects of topical Kiwifruit on healing of neuropathic diabetic foot ulcer

Directory of Open Access Journals (Sweden)

Gholamreza Mohajeri

2014-01-01

Full Text Available Background: Kiwifruit (Actindia Deliciosa is demonstrated to have antibacterial and pro-angiogenic effects. It also contains proteolytic enzymes (actinidin and ascorbic acid. In this study, the effects of Kiwifruit on neuropathic diabetic foot ulcer healing in clinical settings were evaluated. Materials and Methods: In this randomized clinical trial of 37 patients (17 in experimental and 20 in control groups with neuropathic diabetic foot ulcer were studied in Isfahan-Iran. Patients of the control group received just the standard treatments. In the experimental group, in addition to the standard treatments, ulcers were dressed with pure extract of kiwifruit twice daily for 21 days. The ulcers were examined and evaluated based on macroscopic, microscopic and microbiological status. Pre- and post-interventions, biopsies were taken from the ulcers to perform microbiological and histological studies. Results: Mean reduction in surface area of foot ulcer in the experimental group was significantly higher than the control group (168.11 ± 22.31 vs. 88.80 ± 12.04 mm 2 respectively, P < 0.0001. The amount of collagen and granulation tissues was significantly higher in the experimental groups than the control group (P value < 0.0001. Significantly higher levels of angiogenesis and vascularization were found in the kiwifruit treated patients (P value < 0.0001. No significant antibacterial effect was observed for kiwifruit. Conclusion: Natural compounds in the kiwifruit including protein-dissolving enzymes (Actinidin improved different aspects of the wound healing process. Based on these benefits and safety aspects, we conclude that using kiwifruit is a simple, applicable and effective way for treatment of neuropathic diabetic foot ulcer.

Association between ulcer site and outcome in complicated peptic ulcer disease

DEFF Research Database (Denmark)

Lolle, Ida; Møller, Morten Hylander; Rosenstock, Steffen Jais

2016-01-01

OBJECTIVE: Mortality rates in complicated peptic ulcer disease are high. This study aimed to examine the prognostic importance of ulcer site in patients with peptic ulcer bleeding (PUB) and perforated peptic ulcer (PPU). MATERIALS AND METHODS: DESIGN: a nationwide cohort study with prospective...... and adjusted association between ulcer site (gastric and duodenal) and the outcome measures of interest were assessed by binary logistic regression analysis. RESULTS: Some 20,059 patients with PUB and 4273 patients with PPU were included; 90-d mortality was 15.3% for PUB and 29.8% for PPU; 30-d mortality...... was 10.2% and 24.7%, respectively. Duodenal bleeding ulcer, as compared to gastric ulcer (GU), was associated with a significantly increased risk of all-cause mortality within 90 and 30 d, and with re-intervention: adjusted odds ratio (OR) 1.47 (95% confidence interval 1.30-1.67); p 

Preliminary Volcano-Hazard Assessment for Gareloi Volcano, Gareloi Island, Alaska

Science.gov (United States)

Coombs, Michelle L.; McGimsey, Robert G.; Browne, Brandon L.

2008-01-01

Gareloi Volcano (178.794 degrees W and 51.790 degrees N) is located on Gareloi Island in the Delarof Islands group of the Aleutian Islands, about 2,000 kilometers west-southwest of Anchorage and about 150 kilometers west of Adak, the westernmost community in Alaska. This small (about 8x10 kilometer) volcano has been one of the most active in the Aleutians since its discovery by the Bering expedition in the 1740s, though because of its remote location, observations have been scant and many smaller eruptions may have gone unrecorded. Eruptions of Gareloi commonly produce ash clouds and lava flows. Scars on the flanks of the volcano and debris-avalanche deposits on the adjacent seafloor indicate that the volcano has produced large landslides in the past, possibly causing tsunamis. Such events are infrequent, occurring at most every few thousand years. The primary hazard from Gareloi is airborne clouds of ash that could affect aircraft. In this report, we summarize and describe the major volcanic hazards associated with Gareloi.

Aleutian Islands Coastal Resources Inventory and Environmental Sensitivity Maps: VOLCANOS (Volcano Points)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains point locations of active volcanoes as compiled by Motyka et al., 1993. Eighty-nine volcanoes with eruptive phases in the Quaternary are...

[An analysis of clinical characteristics and risk factors for ulceration in ischemic colitis].

Science.gov (United States)

Liu, Wenhui; Liao, Liang; Shi, Hui; Wu, Benyan; Li, Xiaodong; Liu, Yan

2014-08-01

To investigate the clinical manifestations and risk factors related to ulcer in patients with ischemic colitis (IC). Clinical data of sixty-three IC patients with definite diagnosis from June 2002 to June 2012 in the PLA General Hospital were retrospectively analyzed. All patients were classified into ulcer group (23 cases) and non-ulcer group (40 cases) according to the presence of ulcer or not. Clinical manifestations and risk factors related to ulcer lesions were compared in the two groups. Logistic regression model was used for statistical analysis. There were 50 men and 13 women enrolled, with an average age of 70 years old. The main clinical manifestations included abdominal pain [85.7% (54/63) ], diarrhea [54.0% (34/63)], hematochezia [41.3% (26/63)]. In comparison with non-ulcer group, the ulcer group showed higher incidences of chronic constipation [34.8% (8/23) vs 12.5% (5/40) , P = 0.03], enteric-coated aspirin intake [52.2% (12/23) vs 25.0% (10/40), P = 0.03] and abdomen tenderness [82.6% (19/23) vs 52.5% (21/40), P = 0.02]. Chronic constipation and enteric-coated aspirin intake were independent risk factors related to ulcer lesions (OR = 3.38, P = 0.04; OR = 5.91, P = 0.03). Patients with abdomen tenderness had higher incidence of ulcer lesion (OR = 3.12, P = 0.04). The most common location of IC was left colon [69.8% (44/63)]. No difference of site distribution was found in ulcer and non-ulcer group (P = 0.066). Splanchnic atherosclerosis in the ulcer group was more common than in non-ulcer group [88.2% (15/17) vs 58.3% (14/24), P = 0.038]. The duration of hospitalization was significantly longer in ulcer group [ (14.3 ± 7.1) d vs (6.2 ± 4.1) d, P constipation, enteric-coated aspirin intake and splanchnic atherosclerosis are risk factors related to ulcer in IC patients. Abdomen tenderness, high WBC and low Hb strongly indicate possible IC with ulcer.

HYPOCENTER DISTRIBUTION OF LOW FREQUENCY EVENT AT PAPANDAYAN VOLCANO

Directory of Open Access Journals (Sweden)

Muhammad Mifta Hasan

2016-10-01

Full Text Available Papandayan volcano is a stratovolcano with irregular cone-shaped has eight craters around the peak. The most active crater in Papandayan is a Mas crater. Distribution of relocated event calculated using Geiger Adaptive Damping Algorithm (GAD shows that the epicenter of the event centered below Mas crater with maximum rms 0.114. While depth of the hypocenter range between 0-2 km and 5-6 km due to activity of steam and gas.

Organizational changes at Earthquakes & Volcanoes

Science.gov (United States)

Gordon, David W.

1992-01-01

Primary responsibility for the preparation of Earthquakes & Volcanoes within the Geological Survey has shifted from the Office of Scientific Publications to the Office of Earthquakes, Volcanoes, and Engineering (OEVE). As a consequence of this reorganization, Henry Spall has stepepd down as Science Editor for Earthquakes & Volcanoes(E&V).

Source Signature of Sr Isotopes in Fluids Emitting From Mud volcanoes in Taiwan

Science.gov (United States)

Chung, C.; You, C.; Chao, H.

2003-12-01

Located at the boundary between the Philippine Sea Plate and the Asia Continental Plate, abundance of mud volcanoes were erupted on land in Taiwan. According to their occurrences and associated tectonic settings, these mud volcanoes were classified into four groupies. The group (I) mud volcanoes are located in the western coastal plane, whereas group (II) and (III) are situated near the Kutinkung anticline axis and the Chishan fault respectively. The group (IV) mud volcanoes are discovered at the Coastal Range. Although there are numerous studies focused on morphology, possible fluid migration paths and sources are poorly understood. We have collected and analyzed major ions and Sr isotopic ratios in fluids separated from various mud volcanoes in Taiwan. Chemical contents of these fluids were measured by IC and the emitted gasses were analyzed by GC. The Sr concentrations in these fluids were determined using AA and the isotopic compositions were analyzed by TIMS. The dominated ions in fluids are Na and Cl which account for 98% of dissolved materials. All fluids show similar Na/Cl ratios(0.7-0.8), slightly higher than seawater but each group has unique Sr isotopic signature. Waters expelled from group I mud volcanoes featured with low salinity and high Sr isotopic ratios ranged from 0.71150 to 0.71175. Groups II and III were outcroped in the Kutinkung formation but show distinctive chemical compositions. Group II fluids have four times Cl concentrations(358-522mM) compared with those of group III(85-162mM). The latter fluids appear to be more radiogenic(0.71012- 0.71075) indicating possible influence due to water-rock interactions. Low 87Sr/86Sr(0.70692-0.70939) is typical characteristic of mud volcano fluids in group IV where large Mg and K depletion were discovered, suggesting effects due to sediment diagenetic processes. The chemical compositions of mud volcano associated gasses show similar distribution pattern. The major gas constituents in mud volcano zones

The cost of pressure ulcers in the UK.

Science.gov (United States)

Bennett, Gerry; Dealey, Carol; Posnett, John

2004-05-01

To estimate the annual cost of treating pressure ulcers in the UK. Costs were derived from a bottom-up methodology, based on the daily resources required to deliver protocols of care reflecting good clinical practice. Health and social care system in the UK. Patients developing a pressure ulcer. A bottom-up costing approach is used to estimate treatment cost per episode of care and per patient for ulcers of different grades and level of complications. Also, total treatment cost to the health and social care system in the UK. The cost of treating a pressure ulcer varies from pound 1,064 (Grade 1) to pound 10,551 (Grade 4). Costs increase with ulcer grade because the time to heal is longer and because the incidence of complications is higher in more severe cases. The total cost in the UK is pound 1.4- pound 2.1 billion annually (4% of total NHS expenditure). Most of this cost is nurse time. Pressure ulcers represent a very significant cost burden in the UK. Without concerted effort this cost is likely to increase in the future as the population ages. To the extent that pressure ulcers are avoidable, pressure damage may be indicative of clinical negligence and there is evidence that litigation could soon become a significant threat to healthcare providers in the UK, as it is in the USA.

Volcano monitoring with an infrared camera: first insights from Villarrica Volcano

Science.gov (United States)

Rosas Sotomayor, Florencia; Amigo Ramos, Alvaro; Velasquez Vargas, Gabriela; Medina, Roxana; Thomas, Helen; Prata, Fred; Geoffroy, Carolina

2015-04-01

This contribution focuses on the first trials of the, almost 24/7 monitoring of Villarrica volcano with an infrared camera. Results must be compared with other SO2 remote sensing instruments such as DOAS and UV-camera, for the ''day'' measurements. Infrared remote sensing of volcanic emissions is a fast and safe method to obtain gas abundances in volcanic plumes, in particular when the access to the vent is difficult, during volcanic crisis and at night time. In recent years, a ground-based infrared camera (Nicair) has been developed by Nicarnica Aviation, which quantifies SO2 and ash on volcanic plumes, based on the infrared radiance at specific wavelengths through the application of filters. Three Nicair1 (first model) have been acquired by the Geological Survey of Chile in order to study degassing of active volcanoes. Several trials with the instruments have been performed in northern Chilean volcanoes, and have proven that the intervals of retrieved SO2 concentration and fluxes are as expected. Measurements were also performed at Villarrica volcano, and a location to install a ''fixed'' camera, at 8km from the crater, was discovered here. It is a coffee house with electrical power, wifi network, polite and committed owners and a full view of the volcano summit. The first measurements are being made and processed in order to have full day and week of SO2 emissions, analyze data transfer and storage, improve the remote control of the instrument and notebook in case of breakdown, web-cam/GoPro support, and the goal of the project: which is to implement a fixed station to monitor and study the Villarrica volcano with a Nicair1 integrating and comparing these results with other remote sensing instruments. This works also looks upon the strengthen of bonds with the community by developing teaching material and giving talks to communicate volcanic hazards and other geoscience topics to the people who live "just around the corner" from one of the most active volcanoes

Former Buruli Ulcer Patients' Experiences and Wishes May Serve as a Guide to Further Improve Buruli Ulcer Management.

Science.gov (United States)

Velink, Anita; Woolley, Rebecca J; Phillips, Richard O; Abass, Kabiru M; van der Werf, Tjip S; Agumah, Emmanuel; de Zeeuw, Janine; Klis, Sandor; Stienstra, Ymkje

2016-12-01

Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a neglected tropical disease frequently leading to permanent disabilities. The ulcers are treated with rifampicin and streptomycin, wound care and, if necessary surgical intervention. Professionals have exclusively shaped the research agenda concerning management and control, while patients' perspective on priorities and preferences have not explicitly been explored or addressed. To get insight into patient perception of the management and control of Buruli ulcer a mixed methods research design was applied with a questionnaire and focus group discussions among former BU patients. Data collection was obtained in collaboration with a local team of native speakers in Ghana. A questionnaire was completed by 60 former patients and four focus group discussions were conducted with eight participants per group. Former patients positively evaluated both the effectiveness of the treatment and the financial contribution received for the travel costs to the hospitals. Pain experienced during treatment procedures, in particular wound care and the streptomycin injections, and the side-effects of the treatment were negatively evaluated. Former patients considered the development of preventive measures and knowledge on the transmission as priorities. Additionally, former patients asked for improved accessibility of health services, counselling and economic support. These findings can be used to improve clinical management and to guide the international research agenda.

Pressure ulcers in four Indonesian hospitals: prevalence, patient characteristics, ulcer characteristics, prevention and treatment.

Science.gov (United States)

Amir, Yufitriana; Lohrmann, Christa; Halfens, Ruud Jg; Schols, Jos Mga

2017-02-01

The objective of this article was to study characteristics of pressure ulcer patients and their ulcers, pressure ulcer preventive and treatment measures in four Indonesian general hospitals. A multicentre cross-sectional design was applied to assess pressure ulcers and pressure ulcer care in adult patients in medical, surgical, specialised and intensive care units. Ninety-one of the 1132 patients had a total of 142 ulcers. Half (44·0%) already had pressure ulcers before admission. The overall prevalence of category I-IV pressure ulcers was 8·0% (95% CI 6·4-9·6), and the overall nosocomial pressure ulcer prevalence was 4·5% (95% CI 3·3-5·7). Most pressure ulcer patients had friction and shear problems, were bedfast, had diabetes and had more bedridden days. Most ulcers (42·3%) were category III and IV. One third of the patients had both pressure ulcers and moisture lesions (36·3%) and suffered from pain (45·1%). The most frequently used prevention measures were repositioning (61·5%), skin moisturising (47·3%), patient education (36·3%) and massage (35·2%). Most pressure ulcer dressings involved saline-impregnated or antimicrobial gauzes. This study shows the complexities of pressure ulcers in Indonesian general hospitals and reveals that the quality of pressure ulcer care (prevention and treatment) could be improved by implementing the recent evidence-based international guideline. © 2016 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Eruptive viscosity and volcano morphology

International Nuclear Information System (INIS)

Posin, S.B.; Greeley, R.

1988-01-01

Terrestrial central volcanoes formed predominantly from lava flows were classified as shields, stratovolcanoes, and domes. Shield volcanoes tend to be large in areal extent, have convex slopes, and are characterized by their resemblance to inverted hellenic war shields. Stratovolcanoes have concave slopes, whereas domes are smaller and have gentle convex slopes near the vent that increase near the perimeter. In addition to these differences in morphology, several other variations were observed. The most important is composition: shield volcanoes tend to be basaltic, stratovolcanoes tend to be andesitic, and domes tend to be dacitic. However, important exceptions include Fuji, Pico, Mayon, Izalco, and Fuego which have stratovolcano morphologies but are composed of basaltic lavas. Similarly, Ribkwo is a Kenyan shield volcano composed of trachyte and Suswa and Kilombe are shields composed of phonolite. These exceptions indicate that eruptive conditions, rather than composition, may be the primary factors that determine volcano morphology. The objective of this study is to determine the relationships, if any, between eruptive conditions (viscosity, erupted volume, and effusion rate) and effusive volcano morphology. Moreover, it is the goal of this study to incorporate these relationships into a model to predict the eruptive conditions of extraterrestrial (Martian) volcanoes based on their morphology

Cost-effectiveness of wound management in France: pressure ulcers and venous leg ulcers.

Science.gov (United States)

Meaume, S; Gemmen, E

2002-06-01

This study set out to define realistic protocols of care for the treatment of chronic venous leg ulcers and pressure ulcers in France and, by developing cost-effectiveness models, to compare the different protocols of care for the two ulcer groups, enabling a calculation of direct medical costs per ulcer healed in a typical French health insurance plan. Clinical outcomes and some treatment patterns were obtained from published literature. Validations of different treatment patterns were developed using an expert consensus panel similar to the Delphi approach. Costs were calculated based on national averages and estimates from the UK and Germany. The models were used to measure costs per healed ulcer over a 12-week period. For both the pressure ulcer and venous leg ulcer models, three protocols of care were identified. For pressure ulcers and venous leg ulcers, the hydrocolloid DuoDERM (ConvaTec, also known as Granuflex in the UK and Varihesive in Germany) was most cost-effective in France. The combination of published data and expert consensus opinion is a valid technique, and in this case suggests that treating pressure ulcers and venous leg ulcers with hydrocolloid dressings is more cost-effective than treating them with saline gauze, in spite of the lower unit cost of the latter.

Global Volcano Locations Database

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NGDC maintains a database of over 1,500 volcano locations obtained from the Smithsonian Institution Global Volcanism Program, Volcanoes of the World publication. The...

Mud Volcanoes - Analogs to Martian Cones and Domes (by the Thousands!)

Science.gov (United States)

Allen, Carlton C.; Oehler, Dorothy

2010-01-01

Mud volcanoes are mounds formed by low temperature slurries of gas, liquid, sediments and rock that erupt to the surface from depths of meters to kilometers. They are common on Earth, with estimates of thousands onshore and tens of thousands offshore. Mud volcanoes occur in basins with rapidly-deposited accumulations of fine-grained sediments. Such settings are ideal for concentration and preservation of organic materials, and mud volcanoes typically occur in sedimentary basins that are rich in organic biosignatures. Domes and cones, cited as possible mud volcanoes by previous authors, are common on the northern plains of Mars. Our analysis of selected regions in southern Acidalia Planitia has revealed over 18,000 such features, and we estimate that more than 40,000 occur across the area. These domes and cones strongly resemble terrestrial mud volcanoes in size, shape, morphology, associated flow structures and geologic setting. Geologic and mineralogic arguments rule out alternative formation mechanisms involving lava, ice and impacts. We are studying terrestrial mud volcanoes from onshore and submarine locations. The largest concentration of onshore features is in Azerbaijan, near the western edge of the Caspian Sea. These features are typically hundreds of meters to several kilometers in diameter, and tens to hundreds of meters in height. Satellite images show spatial densities of 20 to 40 eruptive centers per 1000 square km. Many of the features remain active, and fresh mud flows as long as several kilometers are common. A large field of submarine mud volcanoes is located in the Gulf of Cadiz, off the Atlantic coasts of Morocco and Spain. High-resolution sonar bathymetry reveals numerous km-scale mud volcanoes, hundreds of meters in height. Seismic profiles demonstrate that the mud erupts from depths of several hundred meters. These submarine mud volcanoes are the closest morphologic analogs yet found to the features in Acidalia Planitia. We are also conducting

Peptic ulcer bleeding patients with Rockall scores ≥6 are at risk of long-term ulcer rebleeding: A 3.5-year prospective longitudinal study.

Science.gov (United States)

Yang, Er-Hsiang; Cheng, Hsiu-Chi; Wu, Chung-Tai; Chen, Wei-Ying; Lin, Meng-Ying; Sheu, Bor-Shyang

2018-01-01

Patients with high Rockall scores have increased risk of rebleeding and mortality within 30 days after peptic ulcer bleeding, but long-term outcomes deserve follow-up after cessation of proton pump inhibitors. The paper aimed to validate whether patients with high Rockall scores have more recurrent ulcer bleeding in a 3.5-year longitudinal cohort. Between August 2011 and July 2014, 368 patients with peptic ulcer bleeding were prospectively enrolled after endoscopic hemostasis to receive proton pump inhibitors for at least 8 to 16 weeks. These subjects were categorized into either a Rockall scores ≥6 group (n = 257) or a Rockall scores ulcer bleeding. The proportion of patients with rebleeding during the 3.5-year follow-up was higher in patients with Rockall scores ≥6 than in those with scores ulcer (P = 0.04) were three additional independent factors found to increase rebleeding risk. The cumulative rebleeding rate was higher in patients with Rockall scores ≥6 with more than or equal to any two additional factors than in those with fewer than two additional factors (15.69 vs. 7.63 per 100 person-year, P = 0.012, log-rank test). Patients with Rockall scores ≥6 are at risk of long-term recurrent peptic ulcer bleeding. The risk can be independently increased by the presence of activated partial thromboplastin time prolonged ≥1.5-fold, American Society of Anesthesiologists class ≥III, and gastric ulcer in patients with Rockall scores ≥6. © 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

Ulcer due to chronic venous disease: a sociodemographic study in northeastern Brazil.

Science.gov (United States)

de Souza, Edson Marques; Yoshida, Winston Bonetti; de Melo, Valdinaldo Aragão; Aragão, José Aderval; de Oliveira, Luiz Augusto Bitencurt

2013-07-01

Venous ulcers account for 70% of chronic leg ulcers and affect about 2-7% of the population, causing much socioeconomic impact and reducing patients' quality of life. In this study we aimed to describe the clinical features of venous ulcers and sociodemographic characteristics of patients with ulcers due to chronic venous disease (CVD). This cross-sectional, observational study was conducted at the Vascular Surgery Service, Universidade Federal de Sergipe, in northeastern Brazil. The study included a consecutive series of 154 patients with active venous ulcers (CEAP C6) in the lower limb due to CVD. Sociodemographic characteristics (age, gender, race, monthly income, education, occupation, and caregiver) and clinical data (affected limb, ulcer site, etiopathogenesis, recurrence, and time elapsed since the first episode of ulcer) were collected. A possible correlation of time elapsed since the first episode of ulcer and number of recurrences with primary or secondary etiology was analyzed by Mann-Whitney U-test. Of the 154 patients analyzed, 79% were female, 94% were ethnically black or brown, 90% had a monthly income less than or equal to minimum wage, 47% were illiterate, 35% had not completed elementary school, 50% had informal jobs, 19.5% were retired, and 18.2% received sick pay from the social security system. The mean age was 53.7 years. Both limbs were affected similarly, and venous ulcers were located predominantly on the medial aspect of the leg (84%). The median time elapsed since the first episode of ulcer was 36 months, being significantly higher in patients with venous ulcers of secondary etiology (P < 0.0003). The prevalence of recurrence was also significantly higher in patients with venous ulcers of secondary etiology (P < 0.001). According to CEAP classification, 65% of ulcers were primary (Ep), 94.1% demonstrated reflux involving the superficial system (As), 92% had incompetent perforators (Ap), 35% demonstrated reflux involving the deep system

Peptic Ulcer Disease

Science.gov (United States)

... Site ACG Patients Home / Digestive Health Topic / Peptic Ulcer Disease Peptic Ulcer Disease Basics Overview An “ulcer” is an open ... for pain in patients at risk for peptic ulcer disease. Peptic – caused by acid. PPIs – P roton P ump ...

Ulcers of stomach body

International Nuclear Information System (INIS)

Oster, A.N.; Rizaev, M.N.

1986-01-01

Symptoms of the roentgenologic image in differential diagnosis of nonmalignant ulcers and stomach carcinomas ulcerated are presented. Problems on X-ray semiotics of ulcerations, data on X-ray represenetation of ulcer evolution as well as postulcer changes in the stomach are interpreted

The prevalence of foot ulceration in patients with rheumatoid arthritis.

Science.gov (United States)

Firth, Jill; Hale, Claire; Helliwell, Philip; Hill, Jackie; Nelson, E Andrea

2008-02-15

To establish the prevalence of foot ulceration in patients with rheumatoid arthritis (RA) in secondary care. A postal survey of all patients with RA (n = 1,130) under the care of rheumatologists in Bradford, West Yorkshire, UK was performed. The prevalence data were validated through clinical examination, case-note review, and contact with health professionals. The false-negative rate was investigated in a subsample of patients (n = 70) who denied any history of ulceration. The postal survey achieved a 78% response rate. Following validation, the point prevalence of foot ulceration was 3.39% and the overall prevalence was 9.73%. The false-positive rate was initially high at 21.21%, but use of diagrammatic questionnaire data to exclude leg ulceration reduced the rate to 10.76%. The false-negative rate was 11.76%. The most common sites for ulceration were the dorsal aspect of hammer toes, the metatarsal heads, and the metatarsophalangeal joint in patients with hallux abducto valgus, with 33% of patients reporting multiple sites of ulceration. Patients with open-foot and healed-foot ulceration had significantly longer RA disease duration, reported significantly greater use of special footwear, and had a higher prevalence of foot surgery than ulcer-free patients. Foot ulceration affects a significant proportion of patients with RA. Further work is needed to establish risk factors for foot ulceration in RA and to target foot health provision more effectively.

A PRESSURE ULCER AND FALL RATE QUALITY COMPOSITE INDEX FOR ACUTE CARE UNITS: A MEASURE DEVELOPMENT STUDY

Science.gov (United States)

Jayawardhana, Ananda; Burman, Mary E.; Dunton, Nancy E.; Staggs, Vincent S.; Bergquist-Beringer, Sandra; Gajewski, Byron J.

2016-01-01

Background Composite indices are single measures that combine the strengths of two or more individual measures and provide broader, easy-to-use measures for evaluation of provider performance and comparisons across units and hospitals to support quality improvement. Objective The study objective was to develop a unit-level inpatient composite nursing care quality performance index – the Pressure Ulcer and Fall Rate Quality Composite Index. Design Two-phase measure development study. Settings 5,144 patient care units in 857 United States hospitals participating in the National Database of Nursing Quality Indictors® during the year 2013. Methods The Pressure Ulcer and Fall Rate Quality Composite Index was developed in two phases. In Phase 1 the formula was generated using a utility function and generalized penalty analysis. Experts with experience in healthcare quality measurement provided the point of indicator equivalence. In Phase 2 initial validity evidence was gathered based on hypothesized relationships between the Pressure Ulcer and Fall Rate Quality Composite Index and other variables using two-level (unit, hospital) hierarchical linear mixed modeling. Results The Pressure Ulcer and Fall Rate Quality Composite Index = 100 − PUR − FR, where PUR is pressure ulcer rate and FR is total fall rate. Higher scores indicate better quality. Bland-Altman plots demonstrated agreement between pairs of experts and provided evidence for inter-rater reliability of the formula. The validation process demonstrated that higher registered nurse skill mix, higher percent of registered nurses with a baccalaureate in nursing or higher degree, higher percent of registered nurses with national specialty certification, and lower percent of hours supplied by agency staff were significantly associated with higher Pressure Ulcer and Fall Rate Quality Composite Index scores. Higher percentages of unit patients at risk for a hospital-acquired pressure ulcer and higher unit rates of

Implementation of a guideline for pressure ulcer prevention in home care: pretest-post-test study.

Science.gov (United States)

Paquay, Louis; Verstraete, Sabine; Wouters, Renild; Buntinx, Frank; Vanderwee, Katrien; Defloor, Tom; Van Gansbeke, Hendrik

2010-07-01

To investigate the effect of the implementation of a patient and family education programme for pressure ulcer prevention in an organisation for home care nursing on guideline adherence and on prevalence and severity of pressure ulcers and to examine the determining factors for the application of measures for pressure ulcer prevention. Quality improvement programmes in pressure ulcer prevention are not always successful. Implementation study using a pretest-post-test design. Data were collected in three probability samples. The first post-test data collection was held after six months, the second after 18 months. Statistical analysis was used, comparing the pretest sample and the second post-test sample. After 18 months, the proportion of subjects with adherent measures had increased from 10·4-13·9%, the proportion of subjects with non-adherent measures decreased from 45·7-36·0%, the proportion of subjects without pressure ulcer prevention increased from 43·9-50·1% (ppressure ulcer prevalence and less severe skin lesions. The nurses' judgement of a patient risk status was the most important factor for applying preventive measures. Furthermore, application of pressure ulcer prevention was determined by higher age (from the age category of 70-79 years), higher dependency for the activities of daily living, higher than baseline mobility score and the presence of a pressure ulcer. Guideline adherence in pressure ulcer prevention changed significantly after implementation of the education programme. There might have been inconsistencies in the nurses' risk judgement. Quality of pressure ulcer prevention improved, but several items for improvement remain. Adaptation of risk assessment procedures is needed. © 2010 Blackwell Publishing Ltd.

History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer.

Science.gov (United States)

Graham, David Y

2014-05-14

Helicobacter pylori (H. pylori) infection underlies gastric ulcer disease, gastric cancer and duodenal ulcer disease. The disease expression reflects the pattern and extent of gastritis/gastric atrophy (i.e., duodenal ulcer with non-atrophic and gastric ulcer and gastric cancer with atrophic gastritis). Gastric and duodenal ulcers and gastric cancer have been known for thousands of years. Ulcers are generally non-fatal and until the 20th century were difficult to diagnose. However, the presence and pattern of gastritis in past civilizations can be deduced based on the diseases present. It has been suggested that gastric ulcer and duodenal ulcer both arose or became more frequent in Europe in the 19th century. Here, we show that gastric cancer and gastric ulcer were present throughout the 17th to 19th centuries consistent with atrophic gastritis being the predominant pattern, as it proved to be when it could be examined directly in the late 19th century. The environment before the 20th century favored acquisition of H. pylori infection and atrophic gastritis (e.g., poor sanitation and standards of living, seasonal diets poor in fresh fruits and vegetables, especially in winter, vitamin deficiencies, and frequent febrile infections in childhood). The latter part of the 19th century saw improvements in standards of living, sanitation, and diets with a corresponding decrease in rate of development of atrophic gastritis allowing duodenal ulcers to become more prominent. In the early 20th century physician's believed they could diagnose ulcers clinically and that the diagnosis required hospitalization for "surgical disease" or for "Sippy" diets. We show that while H. pylori remained common and virulent in Europe and the United States, environmental changes resulted in changes of the pattern of gastritis producing a change in the manifestations of H. pylori infections and subsequently to a rapid decline in transmission and a rapid decline in all H. pylori-related diseases.

Vertical Motions of Oceanic Volcanoes

Science.gov (United States)

Clague, D. A.; Moore, J. G.

2006-12-01

Oceanic volcanoes offer abundant evidence of changes in their elevations through time. Their large-scale motions begin with a period of rapid subsidence lasting hundreds of thousands of years caused by isostatic compensation of the added mass of the volcano on the ocean lithosphere. The response is within thousands of years and lasts as long as the active volcano keeps adding mass on the ocean floor. Downward flexure caused by volcanic loading creates troughs around the growing volcanoes that eventually fill with sediment. Seismic surveys show that the overall depression of the old ocean floor beneath Hawaiian volcanoes such as Mauna Loa is about 10 km. This gross subsidence means that the drowned shorelines only record a small part of the total subsidence the islands experienced. In Hawaii, this history is recorded by long-term tide-gauge data, the depth in drill holes of subaerial lava flows and soil horizons, former shorelines presently located below sea level. Offshore Hawaii, a series of at least 7 drowned reefs and terraces record subsidence of about 1325 m during the last half million years. Older sequences of drowned reefs and terraces define the early rapid phase of subsidence of Maui, Molokai, Lanai, Oahu, Kauai, and Niihau. Volcanic islands, such as Maui, tip down toward the next younger volcano as it begins rapid growth and subsidence. Such tipping results in drowned reefs on Haleakala as deep as 2400 m where they are tipped towards Hawaii. Flat-topped volcanoes on submarine rift zones also record this tipping towards the next younger volcano. This early rapid subsidence phase is followed by a period of slow subsidence lasting for millions of years caused by thermal contraction of the aging ocean lithosphere beneath the volcano. The well-known evolution along the Hawaiian chain from high to low volcanic island, to coral island, and to guyot is due to this process. This history of rapid and then slow subsidence is interrupted by a period of minor uplift

Laboratory volcano geodesy

Science.gov (United States)

Færøvik Johannessen, Rikke; Galland, Olivier; Mair, Karen

2014-05-01

intrusion can be excavated and photographed from several angles to compute its 3D shape with the same photogrammetry method. Then, the surface deformation pattern can be directly compared with the shape of underlying intrusion. This quantitative dataset is essential to quantitatively test and validate classical volcano geodetic models.

Mauna Kea volcano's ongoing 18-year swarm

Science.gov (United States)

Wech, A.; Thelen, W. A.

2017-12-01

Mauna Kea is a large postshield-stage volcano that forms the highest peak on Hawaii Island. The 4,205-meter high volcano erupted most recently between 6,000 and 4,500 years ago and exhibits relatively low rates of seismicity, which are mostly tectonic in origin resulting from lithospheric flexure under the weight of the volcano. Here we identify deep repeating earthquakes occurring beneath the summit of Mauna Kea. These earthquakes, which are not part of the Hawaiian Volcano Observatory's regional network catalog, were initially detected through a systematic search for coherent seismicity using envelope cross-correlation, and subsequent analysis revealed the presence of a long-term, ongoing swarm. The events have energy concentrated at 2-7 Hz, and can be seen in filtered waveforms dating back to the earliest continuous data from a single station archived at IRIS from November 1999. We use a single-station (3 component) match-filter analysis to create a catalog of the repeating earthquakes for the past 18 years. Using two templates created through phase-weighted stacking of thousands of sta/lta-triggers, we find hundreds of thousands of M1.3-1.6 earthquakes repeating every 7-12 minutes throughout this entire time period, with many smaller events occurring in between. The earthquakes occur at 28-31 km depth directly beneath the summit within a conspicuous gap in seismicity surrounding the flanks of the volcano. Magnitudes and periodicity are remarkably stable long-term, but do exhibit slight variability and occasionally display higher variability on shorter time scales. Network geometry precludes obtaining a reliable focal mechanism, but we interpret the frequency content and hypocenters to infer a volcanic source distinct from the regional tectonic seismicity responding to the load of the island. In this model, the earthquakes may result from the slow, persistent degassing of a relic magma chamber at depth.

The deep structure of Axial Volcano

Science.gov (United States)

West, Michael Edwin

The subsurface structure of Axial Volcano, near the intersection of the Juan de Fuca Ridge and the Cobb-Eickelberg seamount chain in the northeast Pacific, is imaged from an active source seismic experiment. At a depth of 2.25 to 3.5 km beneath Axial lies an 8 km x 12 km region of very low seismic velocities that can only be explained by the presence of magma. In the center of this magma storage chamber at 2--3.5 km below sea floor, the crust is at least 10--20% melt. At depths of 4--5 km there is evidence of additional low concentrations of magma (a few percent) over a larger area. In total, 5--11 km3 of magma are stored in the mid-crust beneath Axial. This is more melt than has been positively identified under any basaltic volcano on Earth. It is also far more than the 0.1--0.2 km3 emplaced during the 1998 eruption. The implied residence time in the magma reservoir of a few hundred to a few thousand years agrees with geochemical trends which suggest prolonged storage and mixing of magmas. The large volume of melt bolsters previous observations that Axial provides much of the material to create crust along its 50 km rift zones. A high velocity ring-shaped feature sits above the magma chamber just outside the caldera walls. This feature is believed to be the result of repeated dike injections from the magma body to the surface during the construction of the volcanic edifice. A rapid change in crustal thickness from 8 to 11 km within 15 km of the caldera implies focused delivery of melt from the mantle. The high flux of magma suggests that melting occurs deeper in the mantle than along the nearby ridge. Melt supply to the volcano is not connected to any plumbing system associated with the adjacent segments of the Juan de Fuca Ridge. This suggests that, despite Axial's proximity to the ridge, the Cobb hot spot currently drives the supply of melt to the volcano.

Maintenance therapy with sucralfate in duodenal ulcer: genuine prevention or accelerated healing of ulcer recurrence?

Science.gov (United States)

Bynum, T E; Koch, G G

1991-08-08

We sought to compare the efficacy of sucralfate to placebo for the prevention of duodenal ulcer recurrence and to determine that the efficacy of sucralfate was due to a true reduction in ulcer prevalence and not due to secondary effects such as analgesic activity or accelerated healing. This was a double-blind, randomized, placebo-controlled, parallel groups, multicenter clinical study with 254 patients. All patients had a past history of at least two duodenal ulcers with at least one ulcer diagnosed by endoscopic examination 3 months or less before the start of the study. Complete ulcer healing without erosions was required to enter the study. Sucralfate or placebo were dosed as a 1-g tablet twice a day for 4 months, or until ulcer recurrence. Endoscopic examinations once a month and when symptoms developed determined the presence or absence of duodenal ulcers. If a patient developed an ulcer between monthly scheduled visits, the patient was dosed with a 1-g sucralfate tablet twice a day until the next scheduled visit. Statistical analyses of the results determined the efficacy of sucralfate compared with placebo for preventing duodenal ulcer recurrence. Comparisons of therapeutic agents for preventing duodenal ulcers have usually been made by testing for statistical differences in the cumulative rates for all ulcers developed during a follow-up period, regardless of the time of detection. Statistical experts at the United States Food and Drug Administration (FDA) and on the FDA Advisory Panel expressed doubts about clinical study results based on this type of analysis. They suggested three possible mechanisms for reducing the number of observed ulcers: (a) analgesic effects, (b) accelerated healing, and (c) true ulcer prevention. Traditional ulcer analysis could miss recurring ulcers due to an analgesic effect or accelerated healing. Point-prevalence analysis could miss recurring ulcers due to accelerated healing between endoscopic examinations. Maximum ulcer

Duodenal ulcer and working-class mobility in an African population in South Africa.

Science.gov (United States)

Segal, I; Dubb, A A; Tim, L O; Solomon, A; Sottomayor, M C; Zwane, E M

1978-01-01

The number of Africans in Johannesburg presenting with duodenal ulcers has steadily increased over the past 50 years. The characteristics of 105 patients with duodenal ulcer who presented a Baragwanath Hospital were compared with those of matched and unmatched samples of patients without gastrointestinal conditions in the same hospital. Men with duodenal ulcers were found to be significantly better educated than their controls, most had been born in the town, and more of them were employed at higher, though not the highest, educational levels. These data were used to test Susser's proposition that duodenal ulcers are associated with "early urbanisation." Johannesburg blacks with duodenal ulcer did seem to fit the pattern, but the relation between stress and duodenal ulcer remains unclear. PMID:626837

Are terrestrial plumes from motionless plates analogues to Martian plumes feeding the giant shield volcanoes?

Science.gov (United States)

Meyzen, Christine; Massironi, Matteo; Pozzobon, Riccardo; Dal Zilio, Luca

2014-05-01

The near "one-plate" planet evolution of Mars has led to the edification of long-lasting giant shied volcanoes. Unlike the Earth, Mars would have been a transient convecting planet, where plate tectonic would have possibly acted only during the first hundreds of million years of its history. On Earth, where plate tectonic is active, most of them are regenerated and recycled through convection. However, the Nubian and Antarctic plates could be considered as poorly mobile surfaces of various thicknesses that are acting as conductive lids on top of Earth's deeper convective system. In these environments, volcanoes do not show any linear age progression at least for the last 30 Ma, but constitute the sites of persistent, focused long-term magmatic activity, rather than a chain of volcanoes as observed in fast-moving plate plume environments. Here, the near stationary absolute plate motion probably exerts a primary control on volcanic processes, and more specifically, on the melting ones. The residual depleted mantle, that is left behind by the melting processes, cannot be swept away from the melting locus. Over time, the thickening of this near-stationary depleted layer progressively forces the termination of melting to higher depths, reducing the melt production rate. Such a process gradually leads both to decreasing efficient melt extraction and increasing mantle lithospheric-melt interactions. The accumulation of this refractory material also causes long-term fluctuations of the volcanic activity, in generating long periods of quiescence. The presence of this residual mantle keel induces over time a lateral flow deflection, which translates into a shift of future melting sites around it. This process gives rise to the horseshoe-like shape of some volcanic islands on slow-moving plates (e.g. Cape Verde, Crozet). Finally, the pronounced topographic swells/bulges observed in this environments may also be supported both by large scale mantle upwelling and their residual

Evaluation of four non-invasive methods for examination and characterization of pressure ulcers

DEFF Research Database (Denmark)

Andersen, E.S.; Karlsmark, T.

2008-01-01

Background: Pressure ulcers are globally of major concern and there is need for research in the pathogenesis for early intervention. Early studies have suggested existence of a hypo-echogenic subepidermal layer at the location of pressure ulcers, visualized by ultrasound scans. As a continuation......, we here report on usability of four non-invasive techniques for evaluation of pressure ulcers. Methods: Fifteen pressure ulcers in stage 0-IV were examined using four different non-invasive techniques [redness index, skin temperature, skin elasticity (i.e. retraction time), and ultrasound scanning...... at all pressure ulcers, but none at the reference points. The skin retraction time was often higher at the location of a pressure ulcer than at the reference location. We found no correlation between the stage of the ulcers and temperature, redness index, subepidermal layer thickness, or retraction time...

The cost of pressure ulcers in the United Kingdom.

Science.gov (United States)

Dealey, C; Posnett, J; Walker, A

2012-06-01

To provide an estimate of the costs of treating pressure ulcers in the UK at August 2011 prices, as a means of highlighting the importance of pressure ulcer prevention. Resource use was derived from a bottom-up methodology, based on the daily resources required to deliver protocols of care reflecting good clinical practice, with prices reflecting costs to the health and social care system in the UK. This approach was used to estimate treatment costs per episode of care and per patient for ulcers of different severity and level of complications. The cost of treating a pressure ulcer varies from £1,214 (category 1) to £14,108 (category IV). Costs increase with ulcer severity because the time to heal is longer and the incidence of complications is higher in more severe cases. Pressure ulcers represent a significant cost burden in the UK, both to patients and to health-care providers. Without concerted effort, this cost is likely to increase in the future as the population ages. The estimates reported here provide a basis for assessment of the cost-effectiveness of measures to reduce the incidence of hospital-acquired ulcers. Heron Evidence Development Ltd. was funded for this work by Mölnlycke Health Care (UK). The authors have no other conflicts of interest to declare.

Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding.

Science.gov (United States)

Shiotani, Akiko; Murao, Takahisa; Fujita, Yoshihiko; Fujimura, Yoshinori; Sakakibara, Takashi; Nishio, Kazuto; Haruma, Ken

2014-12-01

In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA). The aim of the present study was to investigate pharmacogenomic profile of LDA-induced peptic ulcer and ulcer bleeding. Patients taking 100 mg of enteric-coated aspirin for cardiovascular diseases and with a peptic ulcer or ulcer bleeding and patients who also participated in endoscopic surveillance were studied. Genome-wide analysis of single nucleotide polymorphisms (SNPs) was performed using the Affymetrix DME Plus Premier Pack. SLCO1B1*1b haplotype and candidate genotypes of genes associated with ulcer bleeding or small bowel bleeding identified by genome-wide analysis were determined using TaqMan SNP Genotyping Assay kits, polymerase chain reaction-restriction fragment length polymorphism, and direct sequencing. Of 593 patients enrolled, 111 patients had a peptic ulcer and 45 had ulcer bleeding. The frequencies of the SLCO1B1*1b haplotype and CHST2 2082 T allele were significantly greater in patients with peptic ulcer and ulcer bleeding compared to the controls. After adjustment for significant factors, the SLCO1B1*1b haplotype was associated with peptic ulcer (OR 2.20, 95% CI 1.24-3.89) and CHST2 2082 T allele with ulcer bleeding (2.57, 1.07-6.17). The CHST2 2082 T allele as well as SLCO1B1*1b haplotype may identify patients at increased risk for aspirin-induced peptic ulcer or ulcer bleeding. © 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

[Evaluation of the Charing Cross Venous Ulcer Questionnaire in patients with chronic venous ulcers in Uruguay].

Science.gov (United States)

Tafernaberry, Gabriela; Otero, Gabriela; Agorio, Caroline; Dapueto, Juan J

2016-01-01

Chronic venous ulcers (CVU) represent a frequent condition, with difficult therapeutic approaches, that impact on patients’ quality of life, and generate an economic burden to patients and health systems. To perform the cultural adaptation and initial evaluation of the Charing Cross Venous Ulcer Questionnaire (CCVUQ) for Uruguay, and to study the health-related quality of life (HRQL) of patients with CVU. The translated and culturally adapted version of the CCVUQ was applied to a convenience sample of 50 patients. In addition, the PROMIS Global Health Survey was included in the assessment. Both questionnaires showed good internal consistency (Cronbach alfa > 0.70). A statistically significant association was observed between the CCVUQ total scores, its subscales and both dimensions of the PROMIS: Global Physical (GPH) and Global Mental Health (GMH) (rho ≥ 0.40). The CCVUQ mean score was 54.9 ± 42 points while GPH and GMH mean scores were 37.9 ± 29 points, and 43.1 ± 35.1 points respectively. Simple linear regression showed that patients with higher income reported better emotional well-being, while in younger patients, ulcers had a higher impact on Emotional Status and Cosmetics. The translated and adapted version of the CCVUQ was easy to comprehend and apply, showing good psychometric properties. When used in association with the PROMIS Global Health Measure it provides complementary information. HRQL was severely affected in the study sample.

Gastroduodenal ulceration in foals.

Science.gov (United States)

Becht, J L; Byars, T D

1986-07-01

Gastroduodenal ulceration is becoming recognised as an important disease in foals during the first few months of life. Aetiopathogenesis is presumed to be similar to peptic disease in humans associated with back diffusion of hydrogen ions into the mucosa. Many factors have been incriminated as predisposing foals to ulceration but few have been proven. To date, use of non-steroidal anti-inflammatory agents has been the only documented cause of gastroduodenal ulceration in foals. The clustering of affected foals on certain farms suggests an infectious aetiology but attempts to identify a causative organism have been unsuccessful. Four clinical syndromes defined for foals with gastroduodenal ulceration include: silent ulcers, which occur most often in the non-glandular stomach along the margo plicatus and are identified as incidental findings at necropsy; active ulcers which are often manifested by abdominal pain, excessive salivation and bruxism; perforating ulcers which usually result in a severe, diffuse peritonitis; and pyloric or duodenal obstruction from a healing ulcer. General approaches to therapy of a foal with active ulceration consist of reduction of gastric acidity and enhancement of mucosal protection. Antacids and type 2 histamine receptor antagonists are used most often to neutralise or decrease acid secretion, respectively. Sucralfate, a locally active sulphated sucrose preparation, is commonly used as a cytoprotective agent. The efficacy and safety of many products used have not been evaluated adequately in foals. Perforating ulcers are usually associated with death or humane destruction of the foal because of fulminating peritonitis. Surgical intervention and bypass procedures are indicated in foals that develop pyloric or duodenal obstructions from healing ulcers.

Stasis dermatitis and ulcers

Science.gov (United States)

... ulcers; Ulcers - venous; Venous ulcer; Venous insufficiency - stasis dermatitis; Vein - stasis dermatitis ... veins. Some people with venous insufficiency develop stasis dermatitis. Blood pools in the veins of the lower ...

Former Buruli Ulcer Patients' Experiences and Wishes May Serve as a Guide to Further Improve Buruli Ulcer Management.

Directory of Open Access Journals (Sweden)

Anita Velink

2016-12-01

Full Text Available Buruli ulcer (BU, caused by Mycobacterium ulcerans, is a neglected tropical disease frequently leading to permanent disabilities. The ulcers are treated with rifampicin and streptomycin, wound care and, if necessary surgical intervention. Professionals have exclusively shaped the research agenda concerning management and control, while patients' perspective on priorities and preferences have not explicitly been explored or addressed.To get insight into patient perception of the management and control of Buruli ulcer a mixed methods research design was applied with a questionnaire and focus group discussions among former BU patients. Data collection was obtained in collaboration with a local team of native speakers in Ghana. A questionnaire was completed by 60 former patients and four focus group discussions were conducted with eight participants per group. Former patients positively evaluated both the effectiveness of the treatment and the financial contribution received for the travel costs to the hospitals. Pain experienced during treatment procedures, in particular wound care and the streptomycin injections, and the side-effects of the treatment were negatively evaluated. Former patients considered the development of preventive measures and knowledge on the transmission as priorities. Additionally, former patients asked for improved accessibility of health services, counselling and economic support.These findings can be used to improve clinical management and to guide the international research agenda.

Seismic Activity at Vailulu'u, Samoa's Youngest Volcano

Science.gov (United States)

Konter, J.; Staudigel, H.; Hart, S.

2002-12-01

Submarine volcanic systems, as a product of the Earth's mantle, play an essential role in the Earth's heat budget and in the interaction between the solid Earth and the hydrosphere and biosphere. Their eruptive and intrusive activity exerts an important control on these hydrothermal systems. In March 2000, we deployed an array of five ocean bottom hydrophones (OBH) on the summit region (625-995 m water depth) of Vailulu'u Volcano (14°12.9'S;169°03.5'W); this volcano represents the active end of the Samoan hotspot chain and is one of only a few well-studied intra-plate submarine volcanoes. We monitored seismic activity for up to 12 months at low sample rate (25 Hz), and for shorter times at a higher sample rate (125 Hz). We have begun to catalogue and locate a variety of acoustic events from this network. Ambient ocean noise was filtered out by a 4th-order Butterworth bandpass filter (2.3 - 10 Hz). We distinguish small local earthquakes from teleseismic activity, mostly identified by T- (acoustic) waves, by comparison with a nearby GSN station (AFI). Most of the detected events are T-phases from teleseismic earthquakes, characterized by their emergent coda and high frequency content (up to 30 Hz); the latter distinguishes them from low frequency emergent signals associated with the volcano (e.g. tremor). A second type of event is characterized by impulsive arrivals, with coda lasting a few seconds. The differences in arrival times between stations on the volcano are too small for these events to be T-waves; they are very likely to be local events, since the GSN station in Western Samoa (AFI) shows no arrivals close in time to these events. Preliminary locations show that these small events occur approximately once per day and are located within the volcano (the 95% confidence ellipse is similar to the size of the volcano, due to the small size of the OBH network). Several events are located relatively close to each other (within a km radius) just NW of the crater.

Peptic Ulcer

Science.gov (United States)

A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your ... Comes and goes for several days or weeks Peptic ulcers happen when the acids that help you digest ...

Stomach ulcer

Science.gov (United States)

... erode the stomach wall. A major cause of stomach ulcers is the bacteria called Helicobacter pylori . Treatment regimens for ulcers caused this bacterium usually include medications to suppress the stomach acid as well as antibiotics to eradicate the ...

Matrix Approach of Seismic Wave Imaging: Application to Erebus Volcano

Science.gov (United States)

Blondel, T.; Chaput, J.; Derode, A.; Campillo, M.; Aubry, A.

2017-12-01

highlight a chimney-shaped structure inside Erebus volcano with true positive rates ranging from 80% to 95%. Although computed independently, the results at each depth are spatially consistent, substantiating their physical reliability. The identified structure is therefore likely to describe accurately the internal structure of the Erebus volcano.

Increased incidence of peptic ulcer disease in central serous chorioretinopathy patients: a population-based retrospective cohort study.

Science.gov (United States)

Chen, San-Ni; Lian, Iebin; Chen, Yi-Chiao; Ho, Jau-Der

2015-02-01

To investigate peptic ulcer disease and other possible risk factors in patients with central serous chorioretinopathy (CSR) using a population-based database. In this population-based retrospective cohort study, longitudinal data from the Taiwan National Health Insurance Research Database were analyzed. The study cohort comprised 835 patients with CSR and the control cohort comprised 4175 patients without CSR from January 2000 to December 2009. Conditional logistic regression was applied to examine the association of peptic ulcer disease and other possible risk factors for CSR, and stratified Cox regression models were applied to examine whether patients with CSR have an increased chance of peptic ulcer disease and hypertension development. The identifiable risk factors for CSR included peptic ulcer disease (adjusted odd ratio: 1.39, P = 0.001) and higher monthly income (adjusted odd ratio: 1.30, P = 0.006). Patients with CSR also had a significantly higher chance of developing peptic ulcer disease after the diagnosis of CSR (adjusted odd ratio: 1.43, P = 0.009). Peptic ulcer disease and higher monthly income are independent risk factors for CSR. Whereas, patients with CSR also had increased risk for peptic ulcer development.

Volcano art at Hawai`i Volcanoes National Park—A science perspective

Science.gov (United States)

Gaddis, Ben; Kauahikaua, James P.

2018-03-26

Long before landscape photography became common, artists sketched and painted scenes of faraway places for the masses. Throughout the 19th century, scientific expeditions to Hawaiʻi routinely employed artists to depict images for the people back home who had funded the exploration and for those with an interest in the newly discovered lands. In Hawaiʻi, artists portrayed the broad variety of people, plant and animal life, and landscapes, but a feature of singular interest was the volcanoes. Painters of early Hawaiian volcano landscapes created art that formed a cohesive body of work known as the “Volcano School” (Forbes, 1992). Jules Tavernier, Charles Furneaux, and D. Howard Hitchcock were probably the best known artists of this school, and their paintings can be found in galleries around the world. Their dramatic paintings were recognized as fine art but were also strong advertisements for tourists to visit Hawaiʻi. Many of these masterpieces are preserved in the Museum and Archive Collection of Hawaiʻi Volcanoes National Park, and in this report we have taken the opportunity to match the artwork with the approximate date and volcanological context of the scene.

Perioperative factors associated with pressure ulcer development after major surgery

Science.gov (United States)

2018-01-01

Background Postoperative pressure ulcers are important indicators of perioperative care quality, and are serious and expensive complications during critical care. This study aimed to identify perioperative risk factors for postoperative pressure ulcers. Methods This retrospective case-control study evaluated 2,498 patients who underwent major surgery. Forty-three patients developed postoperative pressure ulcers and were matched to 86 control patients based on age, sex, surgery, and comorbidities. Results The pressure ulcer group had lower baseline hemoglobin and albumin levels, compared to the control group. The pressure ulcer group also had higher values for lactate levels, blood loss, and number of packed red blood cell (pRBC) units. Univariate analysis revealed that pressure ulcer development was associated with preoperative hemoglobin levels, albumin levels, lactate levels, intraoperative blood loss, number of pRBC units, Acute Physiologic and Chronic Health Evaluation II score, Braden scale score, postoperative ventilator care, and patient restraint. In the multiple logistic regression analysis, only preoperative low albumin levels (odds ratio [OR]: 0.21, 95% CI: 0.05–0.82; P pressure ulcer development. A receiver operating characteristic curve was used to assess the predictive power of the logistic regression model, and the area under the curve was 0.88 (95% CI: 0.79–0.97; P pressure ulcer development after surgery. PMID:29441175

Shape invariant higher-order Bessel-like beams carrying orbital angular momentum

CSIR Research Space (South Africa)

Ismail, Y

2012-09-01

Full Text Available -1 Journal of Optics September 2012/ Vol. 14 Shape invariant higher-order Bessel-like beams carrying orbital angular momentum Y Ismail1,2, N Khilo3, V Belyi3 and A Forbes1,2 1 School of Physics, University of KwaZulu-Natal, Private Bag X54001...

Multiresolution pattern recognition of small volcanos in Magellan data

Science.gov (United States)

Smyth, P.; Anderson, C. H.; Aubele, J. C.; Crumpler, L. S.

1992-01-01

The Magellan data is a treasure-trove for scientific analysis of venusian geology, providing far more detail than was previously available from Pioneer Venus, Venera 15/16, or ground-based radar observations. However, at this point, planetary scientists are being overwhelmed by the sheer quantities of data collected--data analysis technology has not kept pace with our ability to collect and store it. In particular, 'small-shield' volcanos (less than 20 km in diameter) are the most abundant visible geologic feature on the planet. It is estimated, based on extrapolating from previous studies and knowledge of the underlying geologic processes, that there should be on the order of 10(exp 5) to 10(exp 6) of these volcanos visible in the Magellan data. Identifying and studying these volcanos is fundamental to a proper understanding of the geologic evolution of Venus. However, locating and parameterizing them in a manual manner is very time-consuming. Hence, we have undertaken the development of techniques to partially automate this task. The goal is not the unrealistic one of total automation, but rather the development of a useful tool to aid the project scientists. The primary constraints for this particular problem are as follows: (1) the method must be reasonably robust; and (2) the method must be reasonably fast. Unlike most geological features, the small volcanos of Venus can be ascribed to a basic process that produces features with a short list of readily defined characteristics differing significantly from other surface features on Venus. For pattern recognition purposes the relevant criteria include the following: (1) a circular planimetric outline; (2) known diameter frequency distribution from preliminary studies; (3) a limited number of basic morphological shapes; and (4) the common occurrence of a single, circular summit pit at the center of the edifice.

Potential ash impact from Antarctic volcanoes: Insights from Deception Island's most recent eruption.

Science.gov (United States)

Geyer, A; Marti, A; Giralt, S; Folch, A

2017-11-28

Ash emitted during explosive volcanic eruptions may disperse over vast areas of the globe posing a threat to human health and infrastructures and causing significant disruption to air traffic. In Antarctica, at least five volcanoes have reported historic activity. However, no attention has been paid to the potential socio-economic and environmental consequences of an ash-forming eruption occurring at high southern latitudes. This work shows how ash from Antarctic volcanoes may pose a higher threat than previously believed. As a case study, we evaluate the potential impacts of ash for a given eruption scenario from Deception Island, one of the most active volcanoes in Antarctica. Numerical simulations using the novel MMB-MONARCH-ASH model demonstrate that volcanic ash emitted from Antarctic volcanoes could potentially encircle the globe, leading to significant consequences for global aviation safety. Results obtained recall the need for performing proper hazard assessment on Antarctic volcanoes, and are crucial for understanding the patterns of ash distribution at high southern latitudes with strong implications for tephrostratigraphy, which is pivotal to synchronize palaeoclimatic records.

Genital ulcers in women: clinical, microbiologic and histopathologic characteristics.

Science.gov (United States)

Gomes, Christiane Maria Moreira; Giraldo, Paulo César; Gomes, Francis de Assis Moraes; Amaral, Rose; Passos, Mauro Romero Leal; Gonçalves, Ana Katherine da Silveira

2007-04-01

Female genital ulcer is a disease that affects a large number of women, and its etiologic diagnosis can be difficult. The disease may increase the risk of acquiring HIV. Genital ulcer may be present in sexually transmitted diseases (STD)--syphilis, chancroid, genital herpes, donovanosis, lymphogranuloma venereum; and other non-STD disorders (NSTD)--Behçet's syndrome, pemphigus, Crohn's disease, erosive lichen planus and others. This study evaluated the clinical-histopathologic-microbiologic characteristics of female genital ulcers. A cross-sectional descriptive prospective study was conducted during a six-month period to investigate the first 53 women without a definitive diagnosis, seeking medical care for genital ulcers at a genital infections outpatient facility in a university hospital. A detailed and specific history was taken, followed by a dermatologic and gynecologic examination. In addition to collecting material from the lesions for microbiologic study, a biopsy of the ulcer was performed for histopathologic investigation. The average age of the patients was 32.7 years, 56.6% had junior high school education and higher education. The most frequent etiology was herpetic lesion, followed by auto-immune ulcers. At the time of their first consultation, around 60% of the women were using inadequate medication that was inconsistent with the final diagnosis. Histologic diagnosis was conclusive in only 26.4% of the patients (14/53). Cure was obtained in 99% of the cases after proper therapy. The female genital ulcers studied were equally distributed between sexually transmitted and non-sexually transmitted causes. Herpes was the most frequent type of genital ulcer, affecting women indiscriminately, mostly between the ages of 20 and 40 years. The etiologic diagnosis of herpetic ulcers is difficult to make even when various diagnostic methods are applied. It is imperative that NSTD should be included in the differential diagnoses of female genital ulcers. The

Genital ulcers in women: clinical, microbiologic and histopathologic characteristics

Directory of Open Access Journals (Sweden)

Christiane Maria Moreira Gomes

Full Text Available Female genital ulcer is a disease that affects a large number of women, and its etiologic diagnosis can be difficult. The disease may increase the risk of acquiring HIV. Genital ulcer may be present in sexually transmitted diseases (STD - syphilis, chancroid, genital herpes, donovanosis, lymphogranuloma venereum and other non-STD disorders (NSTD - Behçet's syndrome, pemphigus, Crohn's disease, erosive lichen planus and others. This study evaluated the clinical-histopathologic-microbiologic characteristics of female genital ulcers. A cross-sectional descriptive prospective study was conducted during a six-month period to investigate the first 53 women without a definitive diagnosis, seeking medical care for genital ulcers at a genital infections outpatient facility in a university hospital. A detailed and specific history was taken, followed by a dermatologic and gynecologic examination. In addition to collecting material from the lesions for microbiologic study, a biopsy of the ulcer was performed for histopathologic investigation. The average age of the patients was 32.7 years, 56.6% had junior high school education and higher education. The most frequent etiology was herpetic lesion, followed by auto-immune ulcers. At the time of their first consultation, around 60% of the women were using inadequate medication that was inconsistent with the final diagnosis. Histologic diagnosis was conclusive in only 26.4% of the patients (14/53. Cure was obtained in 99% of the cases after proper therapy. The female genital ulcers studied were equally distributed between sexually transmitted and non-sexually transmitted causes. Herpes was the most frequent type of genital ulcer, affecting women indiscriminately, mostly between the ages of 20 and 40 years. The etiologic diagnosis of herpetic ulcers is difficult to make even when various diagnostic methods are applied. It is imperative that NSTD should be included in the differential diagnoses of female

Ulcerative colitis: pathogenesis, diagnosis, and current treatment.

Science.gov (United States)

Griffel, L H; Das, K M

1996-01-01

Ulcerative colitis is a chronic inflammatory disease of the colon that affects the rectum and a variable length of contiguous colon. The disease is characterized by rectal bleeding and diarrhea during periods of exacerbation; these symptoms usually abate with treatment. The pathogenic mechanism of ulcerative colitis is believed to be an aberrant immune response in which antibodies are formed against colonic epithelial protein(s). The disease usually presents during the second and third decades of life, with a smaller peak after the age of 60 years. There is a genetic component to ulcerative colitis, with a higher incidence among family members and, particularly, first-degree relatives. Diagnosis depends on several factors, most notably symptoms, demonstration of uniformly inflamed mucosa beginning in the rectum, and exclusion of other causes of colitis, such as infection. There is no medical cure for ulcerative colitis, but medical therapy is effective and can improve or eliminate symptoms in more than 80% of patients. Surgery offers a cure but carries the high price of total colectomy. New surgical methods, such as ileoanal anastomosis, allow for maintenance of bowel continuity and better patient satisfaction.

Role of dietary polyphenols in the management of peptic ulcer.

Science.gov (United States)

Farzaei, Mohammad Hosein; Abdollahi, Mohammad; Rahimi, Roja

2015-06-07

Peptic ulcer disease is a multifactorial and complex disease involving gastric and duodenal ulcers. Despite medical advances, the management of peptic ulcer and its complications remains a challenge, with high morbidity and death rates for the disease. An accumulating body of evidence suggests that, among a broad reach of natural molecules, dietary polyphenols with multiple biological mechanisms of action play a pivotal part in the management of gastric and duodenal ulcers. The current review confirmed that dietary polyphenols possess protective and therapeutic potential in peptic ulcer mediated by: improving cytoprotection, re-epithelialization, neovascularization, and angiogenesis; up-regulating tissue growth factors and prostaglandins; down-regulating anti-angiogenic factors; enhancing endothelial nitric oxide synthase-derived NO; suppressing oxidative mucosal damage; amplifying antioxidant performance, antacid, and anti-secretory activity; increasing endogenous mucosal defensive agents; and blocking Helicobacter pylori colonization associated gastric morphological changes and gastroduodenal inflammation and ulceration. In addition, anti-inflammatory activity due to down-regulation of proinflammatory cytokines and cellular and intercellular adhesion agents, suppressing leukocyte-endothelium interaction, inhibiting nuclear signaling pathways of inflammatory process, and modulating intracellular transduction and transcription pathways have key roles in the anti-ulcer action of dietary polyphenols. In conclusion, administration of a significant amount of dietary polyphenols in the human diet or as part of dietary supplementation along with conventional treatment can result in perfect security and treatment of peptic ulcer. Further well-designed preclinical and clinical tests are recommended in order to recognize higher levels of evidence for the confirmation of bioefficacy and safety of dietary polyphenols in the management of peptic ulcer.

Mutnovsky and Gorely Volcanoes, Kamchatka as Planetary Analogue Sites

Science.gov (United States)

Evdokimova, N.; Izbekov, P. E.; Krupskaya, V.; Muratov, A.

2016-12-01

Recent advances in Mars studies suggest that volcanic rocks, which dominated Martian surface in the past, have been exposed to alteration processes in a water-bearing environment during Noachian, before 3.7 Gy. Active volcanoes on Earth are natural laboratories, where volcanic processes and their associated products can be studied directly. This is particularly important for studying of alteration of juvenile volcanic products in aqueous environment because of the transient nature of some of the alteration products, as well as the environment itself. Terrestrial analogues help us to better understand processes on Mars; they are particularly useful as a test sites for preparation to future Mars missions. In this presentation we describe planetary analogue sites at Mutnovsky and Gorely Volcanoes in Kamchatka, which might be helpful for comparative studies and preparation to future Mars missions. Mutnovsky and Gorely Volcanoes are located 75 km south of Petropavlovsk-Kamchatsky, in the southern part of the Kamchatka Peninsula, Russia. The modern volcanic landscape in the area was shaped in Holocene (recent 10,000 years) through intermittent eruption of magmas ranging in composition from basalts to dacites and rhyodacites, with basaltic andesite lavas dominating in the modern relief. Two localities could be of a particular interest: (1) Mutnovsky NW thermal field featuring processes of active hydrothermal alteration of lavas of basaltic andesite and (2) dry lake at the bottom of Gorely caldera featuring products of mechanical disintegration of basaltic andesite lavas by eolian processes with short seasonal sedimentation in aqueous environment.

Superficial skin ulcers

International Nuclear Information System (INIS)

Samaila, Modupeola O.; Rafindadi, Abdulmumini H.; Oluwole, Olabode P.; Adewuyi, Sunday A.

2007-01-01

Objective was to determine the underlying cause of superficial skin ulcers over a 15-year period. A retrospective histopathological analysis of 670 cases of superficial skin ulcers diagnosed in the Dept. of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria from January 1991 to December 2005. A total of 670 superficial skin ulcers were analyzed. The mail to female gender ratio was 409:261(1.5:1.0) and a peakage frequency of 44.3 %( 297) in the 5th and 6th decades. Spectrum of lesions encountered was categorized into inflammatory, infections, benign and malignant diseases. The malignant lesions were 309 (46.1%), non-specific inflammation 302 (45.1%), granulation tissue 25 (3.7%) and pseudoepitheliomatous hyperplasia 14 (2.1%). A total of 18(2.7%) specific infections were encountered, which included bacterial, fungal and viral infection. Benign lesions were 2(0.3%), comprising of neurofibroma and Bowen's disease. The most common malignant lesion was squamous cell carcinoma 203 (30.3%) with a male to female ratio of 128:75 (1.7:1.0). Of these 161 were well differentiated tumors. The lower limb was the prevalent site distribution of all the ulcers. Superficial ulcers may be harbinger of malignant diseases. Squamous cell carcinoma remains the most common malignant lesion arising from chronic superficial ulcers from our setting. Adequate tissue biopsy and early diagnosis may reduce the attendant morbidity of these ulcers. (author)

Volcanoes: Coming Up from Under.

Science.gov (United States)

Science and Children, 1980

1980-01-01

Provides specific information about the eruption of Mt. St. Helens in March 1980. Also discusses how volcanoes are formed and how they are monitored. Words associated with volcanoes are listed and defined. (CS)

Exploring Geology on the World-Wide Web--Volcanoes and Volcanism.

Science.gov (United States)

Schimmrich, Steven Henry; Gore, Pamela J. W.

1996-01-01

Focuses on sites on the World Wide Web that offer information about volcanoes. Web sites are classified into areas of Global Volcano Information, Volcanoes in Hawaii, Volcanoes in Alaska, Volcanoes in the Cascades, European and Icelandic Volcanoes, Extraterrestrial Volcanism, Volcanic Ash and Weather, and Volcano Resource Directories. Suggestions…

Peptic ulcer disease - discharge

Science.gov (United States)

... or raw area in the lining of the stomach (gastric ulcer) or upper part of the small intestine (duodenal ... You have peptic ulcer disease (PUD). You may have had tests to help diagnose your ulcer. One of these tests may have ...

Geophysical Observations Supporting Research of Magmatic Processes at Icelandic Volcanoes

Science.gov (United States)

Vogfjörd, Kristín. S.; Hjaltadóttir, Sigurlaug; Roberts, Matthew J.

2010-05-01

Magmatic processes at volcanoes on the boundary between the European and North American plates in Iceland are observed with in-situ multidisciplinary geophysical networks owned by different national, European or American universities and research institutions, but through collaboration mostly operated by the Icelandic Meteorological Office. The terrestrial observations are augmented by space-based interferometric synthetic aperture radar (InSAR) images of the volcanoes and their surrounding surface. Together this infrastructure can monitor magma movements in several volcanoes from the base of the crust up to the surface. The national seismic network is sensitive enough to detect small scale seismicity deep in the crust under some of the voclanoes. High resolution mapping of this seismicity and its temporal progression has been used to delineate the track of the magma as it migrates upwards in the crust, either to form an intrusion at shallow levels or to reach the surface in an eruption. Broadband recording has also enabled capturing low frequency signals emanating from magmatic movements. In two volcanoes, Eyjafjallajökull and Katla, just east of the South Iceland Seismic Zone (SISZ), seismicity just above the crust-mantle boundary has revealed magma intruding into the crust from the mantle below. As the magma moves to shallower levels, the deformation of the Earth‘s surface is captured by geodetic systems, such as continuous GPS networks, (InSAR) images of the surface and -- even more sensitive to the deformation -- strain meters placed in boreholes around 200 m below the Earth‘s surface. Analysis of these signals can reveal the size and shape of the magma as well as the temporal evolution. At near-by Hekla volcano flanking the SISZ to the north, where only 50% of events are of M>1 compared to 86% of earthquakes in Eyjafjallajökull, the sensitivity of the seismic network is insufficient to detect the smallest seismicity and so the volcano appears less

Efficacy of Cellular Therapy for Diabetic Foot Ulcer: A Meta-Analysis of Randomized Controlled Clinical Trials.

Science.gov (United States)

Zhang, Ye; Deng, Hong; Tang, Zhouping

2017-12-01

Diabetes mellitus is a widely spread chronic disease with growing incidence worldwide, and diabetic foot ulcer is one of the most serious complications of diabetes. Cellular therapy has shown promise in the management of diabetic foot ulcer in many preclinical experiments and clinical researches. Here, we performed a meta-analysis to evaluate the efficacy and safety of cellular therapy in the management of diabetic foot ulcer. We systematically searched PubMed, MEDLINE, EMBASE, and Cochrane Library databases from inception to May 2017 for randomized controlled trials assessing the efficacy of cellular therapy in diabetic foot ulcer, and a meta-analysis was conducted. A total of 6 randomized controlled clinical trials involving 241 individuals were included in this meta-analysis. The results suggested that cellular therapy could help accelerating the healing of diabetic foot ulcer, presented as higher ankle-brachial index (mean difference = 0.17, 95% confidence interval [CI] = 0.11 to 0.23), higher transcutaneous oxygen pressure (standardized mean difference [SMD] = 1.43; 95% CI, 1.09- to 1.78), higher ulcer healing rate (relative risk [RR] = 1.78; 95% CI, 1.41 to 2.25), higher amputation-free survival (RR = 1.25; 95% CI, 1.11 to 1.40), and lower scale of pain (SMD = -1.69; 95% CI, -2.05 to -1.33). Furthermore, cellular therapy seemed to be safe, with no serious complications and low risk of short-term slight complications. Cellular therapy could accelerate the rate of diabetic foot ulcer healing and may be more efficient than standard therapy for diabetic foot treatment.

Volcanoes

Science.gov (United States)

... rock, steam, poisonous gases, and ash reach the Earth's surface when a volcano erupts. An eruption can also cause earthquakes, mudflows and flash floods, rock falls and landslides, acid rain, fires, and even tsunamis. Volcanic gas ...

Volcano-Monitoring Instrumentation in the United States, 2008

Science.gov (United States)

Guffanti, Marianne; Diefenbach, Angela K.; Ewert, John W.; Ramsey, David W.; Cervelli, Peter F.; Schilling, Steven P.

2010-01-01

The United States is one of the most volcanically active countries in the world. According to the global volcanism database of the Smithsonian Institution, the United States (including its Commonwealth of the Northern Mariana Islands) is home to about 170 volcanoes that are in an eruptive phase, have erupted in historical time, or have not erupted recently but are young enough (eruptions within the past 10,000 years) to be capable of reawakening. From 1980 through 2008, 30 of these volcanoes erupted, several repeatedly. Volcano monitoring in the United States is carried out by the U.S. Geological Survey (USGS) Volcano Hazards Program, which operates a system of five volcano observatories-Alaska Volcano Observatory (AVO), Cascades Volcano Observatory (CVO), Hawaiian Volcano Observatory (HVO), Long Valley Observatory (LVO), and Yellowstone Volcano Observatory (YVO). The observatories issue public alerts about conditions and hazards at U.S. volcanoes in support of the USGS mandate under P.L. 93-288 (Stafford Act) to provide timely warnings of potential volcanic disasters to the affected populace and civil authorities. To make efficient use of the Nation's scientific resources, the volcano observatories operate in partnership with universities and other governmental agencies through various formal agreements. The Consortium of U.S. Volcano Observatories (CUSVO) was established in 2001 to promote scientific cooperation among the Federal, academic, and State agencies involved in observatory operations. Other groups also contribute to volcano monitoring by sponsoring long-term installation of geophysical instruments at some volcanoes for specific research projects. This report describes a database of information about permanently installed ground-based instruments used by the U.S. volcano observatories to monitor volcanic activity (unrest and eruptions). The purposes of this Volcano-Monitoring Instrumentation Database (VMID) are to (1) document the Nation's existing

Hydrothermal element fluxes from Copahue, Argentina: A "beehive" volcano in turmoil

Science.gov (United States)

Varekamp, J.C.; Ouimette, A.P.; Herman, S.W.; Bermudez, A.; Delpino, D.

2001-01-01

Copahue volcano erupted altered rock debris, siliceous dust, pyroclastic sulfur, and rare juvenile fragments between 1992 and 1995, and magmatic eruptions occurred in July-October 2000. Prior to 2000, the Copahue crater lake, acid hot springs, and rivers carried acid brines with compositions that reflected close to congruent rock dissolution. The ratio between rock-forming elements and chloride in the central zone of the volcano-hydrothermal system has diminished over the past few years, reflecting increased water/rock ratios as a result of progressive rock dissolution. Magmatic activity in 2000 provided fresh rocks for the acid fluids, resulting in higher ratios between rock-forming elements and chloride in the fluids and enhanced Mg fluxes. The higher Mg fluxes started several weeks prior to the eruption. Model data on the crater lake and river element flux determinations indicate that Copahue volcano was hollowed out at a rate of about 20 000-25 000 m3/yr, but that void space was filled with about equal amounts of silica and liquid elemental sulfur. The extensive rock dissolution has weakened the internal volcanic structure, making flank collapse a volcanic hazard at Copahue.

The incidence of duodenal and gastric ulcers in a large health maintenance organization.

Science.gov (United States)

Kurata, J H; Honda, G D; Frankl, H

1985-06-01

We report the incidence of peptic ulcers (duodenal, pyloric canal, gastric, and combined) verified by radiologic, endoscopic, or surgical evidence in a large Health Maintenance Organization (HMO) in Los Angeles, California. For members age 15 and above, the peptic ulcer incidence rate was 0.86 per 1,000 person-years (p-y) (males 1.10, females 0.63). The male to female sex ratio was 1.7. Two hundred twenty-two duodenal, 17 pyloric canal, 89 gastric, and 21 combined first-time diagnosed ulcer cases were located. For duodenal and pyloric canal ulcer, the incidence rate for members age 15 and above was 0.58 per 1,000 p-y (males 0.76, females 0.40). For gastric ulcer, the incidence rate for members age 15 and above was 0.21 per 1,000 p-y (males 0.23, females 0.18). The combined ulcer rate was 0.05 per 1,000 p-y (males 0.07, females 0.02). Gastric ulcer rates were two times higher in 1980 than in 1977. Peptic ulcer age-specific incidence rates increased with age. Incidence rates were much lower than those reported in previous studies, but the gastric to duodenal ulcer ratio and the age and sex relation to ulcer incidence were similar to those previously reported.

Food Sauces to Understand Volcanoes: a Learning Sequence in Middle School

Science.gov (United States)

Pieraccioni, Fabio; Bonaccorsi, Elena; Gioncada, Anna

2017-04-01

Some volcanic processes occur at pressures and temperatures very different from daily experience. Such extreme conditions, unreproducible in the classroom, can lead children to build concepts about volcanic phenomena very different from the reality (Greca & Moreira, 2000; Dove, 1998). The didactic goals of this learning sequence concern the relationships between the viscosity of magmas and types of erupted materials and their consequences on volcano shapes, to favour pupils' comprehension of what a volcano is. Viscosity and its temperature dependence can be easily experimented in class with analogue materials at room temperature (Baker et al., 2004). Our research aims are to observe the development of the thought of pupils of middle schools on volcanic phenomena; this allowed to put in evidence the benefits of this approach and to give suggestions to avoid possible critical points. We have experimented a hands-on learning sequence about volcanoes in four third classes of Tuscan middle schools, for an amount of 95 pupils, 48 females and 47 males. Sharing the principles of constructivism, we think useful that pupils start from their own direct experience for understanding natural phenomena not directly observable. Therefore, we start from the experiences and knowledge of children to build a inquiry-based itinerary (Minner et al., 2010; Pieraccioni et al., 2016). The learning sequence begins with a practical activity in which we employ common and well-known materials to introduce the concept of viscosity in order to relate various kinds of magma to the shape of volcanoes. One of the benefits of this approach is to overcome the problems of introducing complex concepts such as acidity of magmas or silica content, far from the pupils' experience and knowledge. These concepts are often used in Italian middle school textbooks to describe and classify volcanoes. The result is a list of names to learn by heart. On the contrary, by using oil, ketchup, peanut butter or honey

Systematic radon survey over active volcanoes

Energy Technology Data Exchange (ETDEWEB)

Seidel, J.L.; Monnin, M.; Garcia Vindas, J.R. [Centre National de la Recherche Cientifique, Montpellier (France). Lab. GBE; Ricard, L.P.; Staudacher, T. [Observatoire Volcanologique Du Pitou de la Fournaise, La Plaine des Cafres (France)

1999-08-01

Data obtained since 1993 on Costa Rica volcanos are presented and radon anomalies recorded before the eruption of the Irazu volcano (December 8, 1994) are discussed. The Piton de la Fournaise volcano is inactive since mid 1992. The influence of the external parameters on the radon behaviour is studied and the type of perturbations induced on short-term measurements are individuate.

Looking inside volcanoes with the Imaging Atmospheric Cherenkov Telescopes

Science.gov (United States)

Del Santo, M.; Catalano, O.; Cusumano, G.; La Parola, V.; La Rosa, G.; Maccarone, M. C.; Mineo, T.; Sottile, G.; Carbone, D.; Zuccarello, L.; Pareschi, G.; Vercellone, S.

2017-12-01

Cherenkov light is emitted when charged particles travel through a dielectric medium with velocity higher than the speed of light in the medium. The ground-based Imaging Atmospheric Cherenkov Telescopes (IACT), dedicated to the very-high energy γ-ray Astrophysics, are based on the detection of the Cherenkov light produced by relativistic charged particles in a shower induced by TeV photons interacting with the Earth atmosphere. Usually, an IACT consists of a large segmented mirror which reflects the Cherenkov light onto an array of sensors, placed at the focal plane, equipped by fast electronics. Cherenkov light from muons is imaged by an IACT as a ring, when muon hits the mirror, or as an arc when the impact point is outside the mirror. The Cherenkov ring pattern contains information necessary to assess both direction and energy of the incident muon. Taking advantage of the muon detection capability of IACTs, we present a new application of the Cherenkov technique that can be used to perform the muon radiography of volcanoes. The quantitative understanding of the inner structure of a volcano is a key-point to monitor the stages of the volcano activity, to forecast the next eruptive style and, eventually, to mitigate volcanic hazards. Muon radiography shares the same principle as X-ray radiography: muons are attenuated by higher density regions inside the target so that, by measuring the differential attenuation of the muon flux along different directions, it is possible to determine the density distribution of the interior of a volcano. To date, muon imaging of volcanic structures has been mainly achieved with detectors made up of scintillator planes. The advantage of using Cherenkov telescopes is that they are negligibly affected by background noise and allow a consistently improved spatial resolution when compared to the majority of the current detectors.

Pressure ulcers management: an economic evaluation.

Science.gov (United States)

Foglia, E; Restelli, U; Napoletano, A M; Coclite, D; Porazzi, E; Bonfanti, M; Croce, D

2012-03-01

Pressure ulcer management represents a growing problem for medical and social health care systems all over the world, particularly in European Union countries where the incidence of pressure ulcers in older persons (> 60 years of age) is predicted to rise. The aim of this study was to provide evidence for the lower impact on economic resources of using advanced dressings for the treatment of pressure ulcers with respect to conventional simple dressings. Two different models of analysis, derived from Activity Based Costing and Health Technology Assessment, were used to measure, over a 30-day period, the direct costs incurred by pressure ulcer treatment for community-residing patients receiving integrated home care. Although the mean cost per home care visit was higher in the advanced dressings patient group than in the simple dressings patient one (E 22.31 versus E 16.03), analysis of the data revealed that the cost of using advanced dressings was lower due to fewer home care visits (22 versus 11). The results underline the fact that decision-makers need to improve their understanding of the advantages of taking a long-term view with regards to the purchase and use of materials. This could produce considerable savings of resources in addition to improving treatment efficacy for the benefit of patients and the health care system.

[Hormonal mechanisms of pathogenesis and cure of experimental gastroduodenal ulcer by the Okabe technique].

Science.gov (United States)

Frolkov, V K; Polushina, N D; Shvarts, V Ia; Kozharskiĭ, V V; Zaporozhchenko, I G; Kartazaeva, V A

1992-01-01

The dynamics of hormonal secretion was studied in relation with the development of an ulcer defect in rats with acetate-induced gastroduodenal ulcer after Okabe. The formation of the ulcer was accompanied by increased gastrin, glucagon, cortisol, growth hormone, and histamine secretion and reduced glucose tolerance. The level of intragastric pH reduced, the activity of proteolytic enzymes in the gastrointestinal tract increased. Correlation analysis bore evidence for the contribution of gastroenteropancreatic hormones to the compensatory-adaptational responses, whereas with a higher blood cortisol level the surface of the ulcer defect was larger. Oral mineral water (Essentuki No. 17) promoted the secretion of gastrin, glucagon, and insulin and the experimental ulcers grew smaller in this case. The involvement of the hormonal factors in the mechanisms of the development of experimental acetate-induced ulcer is discussed.

Venous ulcers -- self-care

Science.gov (United States)

... surgery to improve blood flow through your veins. Prevention If you are at risk for venous ulcers, take the steps listed above under Wound Care. ... weight if you are overweight. Manage your blood pressure and cholesterol levels. ... Venous leg ulcers - self-care; Venous insufficiency ulcers - self-care; Stasis ...

Unzipping of the volcano arc, Japan

Science.gov (United States)

Stern, R.J.; Smoot, N.C.; Rubin, M.

1984-01-01

A working hypothesis for the recent evolution of the southern Volcano Arc, Japan, is presented which calls upon a northward-progressing sundering of the arc in response to a northward-propagating back-arc basin extensional regime. This model appears to explain several localized and recent changes in the tectonic and magrnatic evolution of the Volcano Arc. Most important among these changes is the unusual composition of Iwo Jima volcanic rocks. This contrasts with normal arc tholeiites typical of the rest of the Izu-Volcano-Mariana and other primitive arcs in having alkaline tendencies, high concentrations of light REE and other incompatible elements, and relatively high silica contents. In spite of such fractionated characteristics, these lavas appear to be very early manifestations of a new volcanic and tectonic cycle in the southern Volcano Arc. These alkaline characteristics and indications of strong regional uplift are consistent with the recent development of an early stage of inter-arc basin rifting in the southern Volcano Arc. New bathymetric data are presented in support of this model which indicate: 1. (1) structural elements of the Mariana Trough extend north to the southern Volcano Arc. 2. (2) both the Mariana Trough and frontal arc shoal rapidly northwards as the Volcano Arc is approached. 3. (3) rugged bathymetry associated with the rifted Mariana Trough is replaced just south of Iwo Jima by the development of a huge dome (50-75 km diameter) centered around Iwo Jima. Such uplifted domes are the immediate precursors of rifts in other environments, and it appears that a similar situation may now exist in the southern Volcano Arc. The present distribution of unrifted Volcano Arc to the north and rifted Mariana Arc to the south is interpreted not as a stable tectonic configuration but as representing a tectonic "snapshot" of an arc in the process of being rifted to form a back-arc basin. ?? 1984.

Impact of pressure ulcers on individuals living with a spinal cord injury.

Science.gov (United States)

Lala, Deena; Dumont, Frédéric S; Leblond, Jean; Houghton, Pamela E; Noreau, Luc

2014-12-01

To describe the impact of pressure ulcers on the ability to participate in daily and community activities, health care utilization, and overall quality of life in individuals living with spinal cord injury (SCI). Cross-sectional study. Nationwide survey. Participants (N=1137) with traumatic SCI who were >1 year postinjury and living in the community were recruited. Of these, 381 (33.5%, 95% confidence interval, 30.8%-36.3%) had a pressure ulcer over the last 12 months. Not applicable. Measures developed for the Rick Hansen Spinal Cord Injury Registry Community Follow-up Survey Version 2.0. Of the 381 individuals with pressure ulcers, 65.3% reported that their pressure ulcer reduced their activity to some extent or more. Pressure ulcers reduced the ability of individuals with SCI to participate in 19 of 26 community and daily activities. Individuals with 1 or 2 pressure ulcers were more dissatisfied with their ability to participate in their main activity than those without pressure ulcers (P=.0077). Pressure ulcers were also associated with a significantly higher number of consultations with family doctors, nurses, occupational therapists, and wound care nurses/specialists (PPressure ulcers have a significant impact on the daily life of individuals with SCI. Our findings highlight the importance of implementing pressure ulcer prevention and management programs for this high-risk population and require the attention of all SCI-related health care professionals. Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Common processes at unique volcanoes – a volcanological conundrum

Directory of Open Access Journals (Sweden)

Katharine eCashman

2014-11-01

Full Text Available An emerging challenge in modern volcanology is the apparent contradiction between the perception that every volcano is unique, and classification systems based on commonalities among volcano morphology and eruptive style. On the one hand, detailed studies of individual volcanoes show that a single volcano often exhibits similar patterns of behaviour over multiple eruptive episodes; this observation has led to the idea that each volcano has its own distinctive pattern of behaviour (or personality. In contrast, volcano classification schemes define eruption styles referenced to type volcanoes (e.g. Plinian, Strombolian, Vulcanian; this approach implicitly assumes that common processes underpin volcanic activity and can be used to predict the nature, extent and ensuing hazards of individual volcanoes. Actual volcanic eruptions, however, often include multiple styles, and type volcanoes may experience atypical eruptions (e.g., violent explosive eruptions of Kilauea, Hawaii1. The volcanological community is thus left with a fundamental conundrum that pits the uniqueness of individual volcanic systems against generalization of common processes. Addressing this challenge represents a major challenge to volcano research.

Frictional-faulting model for harmonic tremor before Redoubt Volcano eruptions

Science.gov (United States)

Dmitrieva, Ksenia; Hotovec-Ellis, Alicia J.; Prejean, Stephanie G.; Dunham, Eric M.

2013-01-01

Seismic unrest, indicative of subsurface magma transport and pressure changes within fluid-filled cracks and conduits, often precedes volcanic eruptions. An intriguing form of volcano seismicity is harmonic tremor, that is, sustained vibrations in the range of 0.5–5 Hz. Many source processes can generate harmonic tremor. Harmonic tremor in the 2009 eruption of Redoubt Volcano, Alaska, has been linked to repeating earthquakes of magnitudes around 0.5–1.5 that occur a few kilometres beneath the vent. Before many explosions in that eruption, these small earthquakes occurred in such rapid succession—up to 30 events per second—that distinct seismic wave arrivals blurred into continuous, high-frequency tremor. Tremor abruptly ceased about 30 s before the explosions. Here we introduce a frictional-faulting model to evaluate the credibility and implications of this tremor mechanism. We find that the fault stressing rates rise to values ten orders of magnitude higher than in typical tectonic settings. At that point, inertial effects stabilize fault sliding and the earthquakes cease. Our model of the Redoubt Volcano observations implies that the onset of volcanic explosions is preceded by active deformation and extreme stressing within a localized region of the volcano conduit, at a depth of several kilometres.

Recurring pressure ulcers: identifying the definitions. A National Pressure Ulcer Advisory Panel white paper.

Science.gov (United States)

Tew, Cindy; Hettrick, Heather; Holden-Mount, Sarah; Grigsby, Rebekah; Rhodovi, Julie; Moore, Lyn; Ghaznavi, Amir M; Siddiqui, Aamir

2014-01-01

Currently, there is a lack of consensus regarding the accepted terminology pertaining to the pressure ulcer healing progression and recidivism. This lack of uniformity can negatively impact initiation of treatment pathways, completion of appropriate interventions, clinical documentation, medical coding, patient education, discharge planning and healthcare revenue through out the healthcare system. The purpose of this paper is to introduce a standard nomenclature as it pertains to pressure ulcer healing progression and any recidivism that may occur. The National Pressure Ulcer Advisory Panel has formulated a framework of terms regarding pressure ulcer progression. We also developed a clearer nomenclature for lack of progress and recidivism of pressure ulcers. This document should serve as a starting point for the discussion of the pressure ulcer care, research, and terminology. © 2014 by the Wound Healing Society.

The management of large perforations of duodenal ulcers

Directory of Open Access Journals (Sweden)

Sharma Rajeev

2005-06-01

Full Text Available Abstract Background Duodenal ulcer perforations are a common surgical emergency, but literature is silent on the exact definition, incidence, management and complications of large perforations of duodenal ulcers. Methods The case files of 162 patients who underwent emergency laparotomy for duodenal ulcer perforations over a period of three years (2001 – 2003 were retrospectively reviewed and sorted into groups based on the size of the perforations – one group was defined as 'small 'perforations (less than 1 cm in diameter, another 'large' (when the perforation was more than 1 cm but less than 3 cms, and the third, 'giant'(when the perforation exceeded 3 cm. These groups of patients were then compared with each other in regard to the patient particulars, duration of symptoms, surgery performed and the outcome. Results A total of 40 patients were identified to have duodenal ulcer perforations more than 1 cm in size, thus accounting for nearly 25 % of all duodenal ulcer perforations operated during this period. These patients had a significantly higher incidence of leak, morbidity and mortality when compared to those with smaller perforations. Conclusion There are three distinct types of perforations of duodenal ulcers that are encountered in clinical practice. The first, are the 'small' perforations that are easy to manage and have low morbidity and mortality. The second are the 'large' perforations, that are also not uncommon, and omental patch closure gives the best results even in this subset of patients. The word 'giant' should be reserved for perforations that exceed 3 cms in diameter, and these are extremely uncommon.

Alaska volcanoes guidebook for teachers

Science.gov (United States)

Adleman, Jennifer N.

2011-01-01

Alaska’s volcanoes, like its abundant glaciers, charismatic wildlife, and wild expanses inspire and ignite scientific curiosity and generate an ever-growing source of questions for students in Alaska and throughout the world. Alaska is home to more than 140 volcanoes, which have been active over the last 2 million years. About 90 of these volcanoes have been active within the last 10,000 years and more than 50 of these have been active since about 1700. The volcanoes in Alaska make up well over three-quarters of volcanoes in the United States that have erupted in the last 200 years. In fact, Alaska’s volcanoes erupt so frequently that it is almost guaranteed that an Alaskan will experience a volcanic eruption in his or her lifetime, and it is likely they will experience more than one. It is hard to imagine a better place for students to explore active volcanism and to understand volcanic hazards, phenomena, and global impacts. Previously developed teachers’ guidebooks with an emphasis on the volcanoes in Hawaii Volcanoes National Park (Mattox, 1994) and Mount Rainier National Park in the Cascade Range (Driedger and others, 2005) provide place-based resources and activities for use in other volcanic regions in the United States. Along the lines of this tradition, this guidebook serves to provide locally relevant and useful resources and activities for the exploration of numerous and truly unique volcanic landscapes in Alaska. This guidebook provides supplemental teaching materials to be used by Alaskan students who will be inspired to become educated and prepared for inevitable future volcanic activity in Alaska. The lessons and activities in this guidebook are meant to supplement and enhance existing science content already being taught in grade levels 6–12. Correlations with Alaska State Science Standards and Grade Level Expectations adopted by the Alaska State Department of Education and Early Development (2006) for grades six through eleven are listed at

A Volcano Exploration Project Pu`u `O`o (VEPP) Exercise: Is Kilauea in Volcanic Unrest? (Invited)

Science.gov (United States)

Schwartz, S. Y.

2010-12-01

Volcanic activity captures the interest and imagination of students at all stages in their education. Analysis of real data collected on active volcanoes can further serve to engage students in higher-level inquiry into the complicated physical processes associated with volcanic eruptions. This exercise takes advantage of both student fascination with volcanoes and the recognized benefits of incorporating real, internet-accessible data to achieve its goals of enabling students to: 1) navigate a scientific website; 2) describe the physical events that produce volcano monitoring data; 3) identify patterns in geophysical time-series and distinguish anomalies preceding and synchronous with eruptive events; 4) compare and contrast geophysical time series and 5) integrate diverse data sets to assess the eruptive state of Kilauea volcano. All data come from the VEPP website (vepp.wr.usgs.gov) which provides background information on the historic activity and volcano monitoring methods as well as near-real time volcano monitoring data from the Pu`u `O`o eruptive vent on Kilauea Volcano. This exercise, designed for geology majors, has students initially work individually to acquire basic skills with volcano monitoring data interpretation and then together in a jigsaw activity to unravel the events leading up to and culminating in the July 2007 volcanic episode. Based on patterns established prior to the July 2007 event, students examine real-time volcano monitoring data to evaluate the present activity level of Kilauea volcano. This exercise will be used for the first time in an upper division Geologic Hazards class in fall 2010 and lessons learned including an exercise assessment will be presented.

Pressure Ulcers

OpenAIRE

Monfre, Jill M.

2016-01-01

Unrelieved pressure or friction of the skin, particularly over bony prominences, can lead to pressure ulcers, which affect up to one third of people in hospitals or community care, and one fifth of nursing home residents. Pressure ulcers are more likely in people with reduced mobility and poor skin condition, such as older people or those with vascular disease.

Peptic ulcer perforation

African Journals Online (AJOL)

FinePrint

2015-06-01

Jun 1, 2015 ... Peptic ulcer perforation is one of the surgical complications of peptic ulcer ... Treatment can be operative or non-operative followed by proton .... chronic gastritis without evidence of ... inhibits pancreatic bicarbonate secretion.

[MEASUREMENT OF HISTONES AND CIRCULATING EXTRACELLULAR NUCLEIC ACIDS IN PATIENTS' WITH COMPLICATED FORMS OF PEPTIC ULCER].

Science.gov (United States)

Yerznkyan, G; Kultanov, B; Shakeev, K; Tatina, Ye

2017-04-01

We studied 135 people (24 people, apparently healthy, 39 uncomplicated peptic ulcer disease, 42 people with complex forms peptic ulcer, 30 and after the treatment of complicated forms of peptic ulcer disease, both sexes (18-45 y.). In all patients, the diagnosis was confirmed fibrogastroduodenoscopy (EGD). Determination of histones and acid soluble fraction (ASF), RNA, DNA, in blood was performed by the method of L. Markusheva. Studies have led to the conclusion that the change in the blood concentration of extracellular nucleic acids in patients with uncomplicated disease and complex shapes can be caused by oxidative stress products and can be a signal for elimination of nucleic acids from cells. We have registered various dynamics of the studied parameters histones in the blood of patients with various forms of peptic ulcer disease, which reflects the degree of metabolic abnormalities that occur in the body, associated with changes in the structure of the nucleus. According to the results of our research in the study of the role of extracellular nucleic acids, histones to assess the extent of violations of metabolic processes at a peptic ulcer, complicated and uncomplicated form, the obtained results can be used as predictors of complications of a stomach ulcer.

Volcano-tectonic interactions at Sabancaya and other Peruvian volcanoes revealed by InSAR and seismicity

Science.gov (United States)

Jay, J.; Pritchard, M. E.; Aron, F.; Delgado, F.; Macedo, O.; Aguilar, V.

2013-12-01

An InSAR survey of all 13 Holocene volcanoes in the Andean Central Volcanic Zone of Peru reveals previously undocumented surface deformation that is occasionally accompanied by seismic activity. Our survey utilizes SAR data spanning from 1992 to the present from the ERS-1, ERS-2, and Envisat satellites, as well as selected data from the TerraSAR-X satellite. We find that the recent unrest at Sabancaya volcano (heightened seismicity since 22 February 2013 and increased fumarolic output) has been accompanied by surface deformation. We also find two distinct deformation episodes near Sabancaya that are likely associated with an earthquake swarm in February 2013 and a M6 normal fault earthquake that occurred on 17 July 2013. Preliminary modeling suggests that faulting from the observed seismic moment can account for nearly all of the observed deformation and thus we have not yet found clear evidence for recent magma intrusion. We also document an earlier episode of deformation that occurred between December 2002 and September 2003 which may be associated with a M5.3 earthquake that occurred on 13 December 2002 on the Solarpampa fault, a large EW-striking normal fault located about 25 km northwest of Sabancaya volcano. All of the deformation episodes between 2002 and 2013 are spatially distinct from the inflation seen near Sabancaya from 1992 to 1997. In addition to the activity at Sabancaya, we also observe deformation near Coropuna volcano, in the Andagua Valley, and in the region between Ticsani and Tutupaca volcanoes. InSAR images reveal surface deformation that is possibly related to an earthquake swarm near Coropuna and Sabancaya volcanoes in December 2001. We also find persistent deformation in the scoria cone and lava field along the Andagua Valley, located 40 km east of Corpuna. An earthquake swarm near Ticsani volcano in 2005 produced surface deformation centered northwest of the volcano and was accompanied by a north-south elongated subsidence signal to the

Gouge marks on deep-sea mud volcanoes in the eastern Mediterranean: Caused by Cuvier’s beaked whales?

NARCIS (Netherlands)

Woodside, J.M.; David, L; Frantzis, A.; Hooker, S.K.

2006-01-01

Enigmatic seafloor gouge marks at depths of 1700-2100 m have been observed from submersible during geological survey work studying mud volcanoes in the eastern Mediterranean Sea. The marks consist of a central groove (about 10 cm deep and 1-2 m long), superimposed on a broader bowl-shaped depression

Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study.

Science.gov (United States)

Sverdén, Emma; Brusselaers, Nele; Wahlin, Karl; Lagergren, Jesper

2017-12-09

Helicobacter pylori is associated with peptic ulcer disease and gastric cancer. Therefore we wanted to test how various lengths of delays in H pylori eradication therapy influence the risk of recurrent peptic ulcer, ulcer adverse events, and gastric cancer. This population-based nationwide Swedish cohort study included 29,032 patients receiving H pylori eradication therapy after peptic ulcer disease in 2005 to 2013. Predefined time intervals between date of peptic ulcer diagnosis and date of eradication therapy were analyzed in relation to study outcomes. Cox regression provided hazard ratios (HRs) and 95% confidence intervals (95% CIs), adjusted for age, sex, comorbidity, history of ulcer disease, use of ulcerogenic drugs, and use of proton pump inhibitors (PPIs). Compared with eradication therapy within 7 days of peptic ulcer diagnosis, eradication therapy within 8 to 30, 31 to 60, 61 to 365, and >365 days corresponded with HRs of recurrent ulcer of 1.17 (95% CI, 1.08-1.25), 2.37 (95% CI, 2.16-2.59), 2.96 (95% CI, 2.76-3.16), and 3.55 (95% CI, 3.33-3.79), respectively. The corresponding HRs for complicated ulcer were 1.55 (95% CI, 1.35-1.78), 3.19 (95% CI, 2.69-3.78), 4.00 (95% CI, 3.51-4.55), and 6.14, (95% CI, 5.47-6.89), respectively. For gastric cancer the corresponding HRs were .85 (95% CI, .32-2.23), 1.31 (95% CI, .31-5.54), 3.64 (95% CI, 1.55-8.56), and 4.71 (95% CI, 2.36-9.38), respectively. Delays in H pylori eradication therapy after peptic ulcer diagnosis time-dependently increase the risk of recurrent ulcer, even more so for complicated ulcer, starting from delays of 8 to 30 days. Copyright © 2017 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

Ulcerative giant solitary trichoepithelioma of scalp: a rare presentation

Directory of Open Access Journals (Sweden)

Sundeep Chowdhry

2016-07-01

Full Text Available Trichoepithelioma is a trichogenic tumor which arises from the inferior segment of hair follicle epithelium as hamartoma. Giant solitary trichoepithelioma (GST has been defined as a solitary trichoepithelioma with a diameter greater than 2 cm. A 49-year-old female presented with a slow growing skin coloured swelling on the scalp of 8 years duration with recent history of ulceration and occasional bleeding. The local examination revealed a single well defined nodular swelling which was irregular in shape measuring approximately 2 × 2.5 cm. Histopathology from biopsy specimen revealed dark basaloid cells with scanty cytoplasm and darkly stained nucleus arranged in nests with horn cysts lacking high-grade atypia and mitosis, which was consistent with features of trichoepithelioma. Giant solitary trichoepithelioma of scalp is itself a rare entity and the present case is being reported with the additional component of ulceration in the lesion.

Radiation induced esophageal ulcer

International Nuclear Information System (INIS)

Kawano, Tatsuyuki; Endo, Mitsuo; Yamazaki, Shigeru

1990-01-01

A 77-year-old woman was referred to us on Dec. 22, 1986 because of dysphagia and esophageal ulcer. She had a previous history of left radical mastectomy for breast cancer, followed by postoperative 60 Co irradiation to parasternal and supraclavicular regions with 50 Gy about 15 years before. UGIs and endoscopy showed a small ulcer surrounded by submucosal tumor-like protrusion in the esophagus at the thoracic inlet. Examination one month later revealed the ulcer which became larger despite medical treatment, now measuring 1 cm in diameter. Severe dysphagia continued. Right thoractomy and subtotal esophagectomy were performed on Jan 13, 1987. Histological examination revealed nonspecific ulcer, 5 cm in diameter, surrounded by fibrous granulation tissue. Proliferation of dilated capillary vessels was also seen in the bottom of the ulcer, the surrounding wall of which was free from remarkable infiltration of inflammatory cells. Based on these findings and previous medical history, the patient was diagnosed as having a postirradiation ulcer which appeared 15 years after irradiation. Dysphagia was considered due to esophageal dysfunction caused by severe fibrosis of the proper muscle layer. (author)

Long-term behavior of aortic intramural hematomas and penetrating ulcers.

Science.gov (United States)

Chou, Alan S; Ziganshin, Bulat A; Charilaou, Paris; Tranquilli, Maryann; Rizzo, John A; Elefteriades, John A

2016-02-01

For intramural hematoma and penetrating atherosclerotic ulcer, long-term behavior and treatment are controversial. This study evaluates the long-term behavior of intramural hematoma and penetrating atherosclerotic ulcer, including radiologic follow-up and survival analysis. Between 1995 and 2014, 108 patients (mean age, 70.8 ± 10 years; 56% female) presented with intramural hematoma or penetrating atherosclerotic ulcer to Yale-New Haven Hospital (New Haven, Conn). We reviewed the medical records, radiology, and online mortality databases. Ten of 55 patients (18%) with intramural hematoma and 17 of 53 patients (32%) with penetrating atherosclerotic ulcer had rupture state symptoms on admission, both greater than type A (8%) or type B dissection (4%) (P hematoma with follow-up imaging, 8 of 14 (57%) worsened (mean follow-up, 9.4 months) and 6 (43%) underwent late surgery. For patients with penetrating atherosclerotic ulcer with follow-up imaging, 6 of 20 (30%) worsened and underwent late surgery, and 11 (55%) showed no change (mean follow-up, 34.3 months). Overall survivals were 77%, 70%, 58%, and 33% at 1, 3, 5, and 10 years, respectively. No operative deaths occurred for patients with nonrupture state. Patients with penetrating atherosclerotic ulcer with initial surgical treatment had better long-term survival than patients treated medically (P = .037). In the intramural hematoma group, no such difference was observed (P = .10). At presentation, the incidence of early rupture of intramural hematoma and penetrating atherosclerotic ulcer was higher than for typical dissection. For branch vessels, intramural hematoma never occludes branch arteries. On imaging follow-up, patients with intramural hematoma and penetrating atherosclerotic ulcer rarely improved, with late surgery commonly needed. Better survival was observed for the initial surgical management of patients with penetrating atherosclerotic ulcer compared with initial medical management. Copyright © 2016

Nicorandil, Gastrointestinal Adverse Drug Reactions and Ulcerations: A Systematic Review.

Science.gov (United States)

Pisano, Umberto; Deosaran, Jordanna; Leslie, Stephen J; Rushworth, Gordon F; Stewart, Derek; Ford, Ian; Watson, Angus J M

2016-03-01

Nicorandil is a popular anti-anginal drug in Europe and Japan. Apart from some common adverse drug reactions (ADR), its safety is satisfactory. Several reports have suggested a link between nicorandil, gastrointestinal (GI) ulceration and fistulas. The review aims to critically appraise, synthesize and present the available evidence of all known GI ADR per anatomical location. The study complied with the PRISMA statement. Literature and pharmacovigilance databases were used to provide rate and/or calculate parameters (median age, median dose, history of symptoms, length of therapy and healing time after withdrawal of the drug). Differences in distribution of quantitative variables were analyzed via Mann-Whitney test. Correlation between quantitative variables was assessed with a Spearman's correlation coefficient. A p value <0.05 was significant. Oral ulcerations occur in 0.2% of the subjects, anal ulcerations are present between 0.07% and 0.37% of patients. Oral and distal GI involvements are the most common ADR (28-29% and 27-31% of all GI ADR, respectively). The hepatobiliary system, the pancreas and salivary glands are not affected by nicorandil exposure. The time to develop oral ulcerations is 74 weeks among people on <30 mg/day compared to only 7.5 weeks in individuals on higher regimens (p = 0.47). There is a significant correlation between dose and ulcer healing time (Spearman's 0.525, p < 0.001). Ulcerative disease is a very commonly reported GI ADR. A delayed ulcerative tendency supports the hypothesis of an ulcerogenic metabolite. Nicorandil seems to act as a cause of the ulcerations, but appears to also work in synergy with other promoting factors. Whether the action of the metabolites relies on a specific mechanism or a simple chemical ulceration is still to be established.

Is Helicobacter pylori Infection the Primary Cause of Duodenal Ulceration or a Secondary Factor? A Review of the Evidence

Directory of Open Access Journals (Sweden)

Vikram Kate

2013-01-01

Full Text Available Helicobacter pylori (H. pylori has a role in the multifactorial etiology of peptic ulcer disease. A link between H. pylori infection and duodenal ulcer disease is now established. Other contributing factors and their interaction with the organism may initiate the ulcerative process. The fact that eradication of H. pylori infection leads to a long-term cure in the majority of duodenal ulcer patients and the fact that the prevalence of infection is higher in ulcer patients than in the normal population are cogent arguments in favor of it being the primary cause of the ulceration. Against this concept there are issues that need explanation such as the reason why only a minority of infected persons develop duodenal ulceration when infection with H. pylori is widespread. There is evidence that H. pylori infection has been prevalent for several centuries, yet duodenal ulceration became common at the beginning of the twentieth century. The prevalence of duodenal ulceration is not higher in countries with a high prevalence of H. pylori infection. This paper debate puts forth the point of view of two groups of workers in this field whether H. pylori infection is the primary cause of duodenal ulcer disease or a secondary factor.

Measurements of radon and chemical elements: Popocatepetl volcano; Mediciones de radon y elementos quimicos: Volcan Popocatepetl

Energy Technology Data Exchange (ETDEWEB)

Pena, P.; Segovia, N.; Lopez, B.; Reyes, A.V. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico); Armienta, M.A.; Valdes, C.; Mena, M. [IGFUNAM, Ciudad Universitaria, 04510 Mexico D.F. (Mexico); Seidel, J.L.; Monnin, M. [UMR 5569 CNRS Hydrosciences, Montpellier (France)

2002-07-01

The Popocatepetl volcano is a higher risk volcano located at 60 Km from Mexico City. Radon measurements on soil in two fixed seasons located in the north slope of volcano were carried out. Moreover the radon content, major chemical elements and tracks in water samples of three springs was studied. The radon of soil was determined with solid detectors of nuclear tracks (DSTN). The radon in subterranean water was evaluated through the liquid scintillation method and it was corroborated with an Alpha Guard equipment. The major chemical elements were determined with conventional chemical methods and the track elements were measured using an Icp-Ms equipment. The radon on soil levels were lower, indicating a moderate diffusion of the gas across the slope of the volcano. The radon in subterranean water shown few changes in relation with the active scene of the volcano. The major chemical elements and tracks showed a stable behavior during the sampling period. (Author)

Volcano warning systems: Chapter 67

Science.gov (United States)

Gregg, Chris E.; Houghton, Bruce F.; Ewert, John W.

2015-01-01

Messages conveying volcano alert level such as Watches and Warnings are designed to provide people with risk information before, during, and after eruptions. Information is communicated to people from volcano observatories and emergency management agencies and from informal sources and social and environmental cues. Any individual or agency can be both a message sender and a recipient and multiple messages received from multiple sources is the norm in a volcanic crisis. Significant challenges to developing effective warning systems for volcanic hazards stem from the great diversity in unrest, eruption, and post-eruption processes and the rapidly advancing digital technologies that people use to seek real-time risk information. Challenges also involve the need to invest resources before unrest to help people develop shared mental models of important risk factors. Two populations of people are the target of volcano notifications–ground- and aviation-based populations, and volcano warning systems must address both distinctly different populations.

Global Volcano Mortality Risks and Distribution

Data.gov (United States)

National Aeronautics and Space Administration — Global Volcano Mortality Risks and Distribution is a 2.5 minute grid representing global volcano mortality risks. The data set was constructed using historical...

Giant duodenal ulcers

Institute of Scientific and Technical Information of China (English)

Eric Benjamin Newton; Mark R Versland; Thomas E Sepe

2008-01-01

Giant duodenal ulcers (GDUs) are a subset of duodenal ulcers that have historically resulted in greater morbidity than usual duodenal ulcers. Until recently,few cases had been successfully treated with medical therapy. However, the widespread use of endoscopy,the introduction of H-2 receptor blockers and proton pump inhibitors, and the improvement in surgical techniques all have revolutionized the diagnosis,treatment and outcome of this condition. Nevertheless,GDUs are still associated with high rates of morbidity,mortality and complications. Thus, surgical evaluation of a patient with a GDU should remain an integral part of patient care. These giant variants, while usually benign, can frequently harbor malignancy. A careful review of the literature highlights the important differences when comparing GDUs to classical peptic ulcers and why they must be thought of differently than their more common counterpart.

Lahar hazards at Agua volcano, Guatemala

Science.gov (United States)

Schilling, S.P.; Vallance, J.W.; Matías, O.; Howell, M.M.

2001-01-01

At 3760 m, Agua volcano towers more than 3500 m above the Pacific coastal plain to the south and 2000 m above the Guatemalan highlands to the north. The volcano is within 5 to 10 kilometers (km) of Antigua, Guatemala and several other large towns situated on its northern apron. These towns have a combined population of nearly 100,000. It is within about 20 km of Escuintla (population, ca. 100,000) to the south. Though the volcano has not been active in historical time, or about the last 500 years, it has the potential to produce debris flows (watery flows of mud, rock, and debris—also known as lahars when they occur on a volcano) that could inundate these nearby populated areas.

Hydrothermal element fluxes from Copahue, Argentina: A “beehive” volcano in turmoil

Science.gov (United States)

Varekamp, Johan C.; Ouimette, Andrew P.; Herman, Scott W.; Bermúdez, Adriana; Delpino, Daniel

2001-11-01

Copahue volcano erupted altered rock debris, siliceous dust, pyroclastic sulfur, and rare juvenile fragments between 1992 and 1995, and magmatic eruptions occurred in July October 2000. Prior to 2000, the Copahue crater lake, acid hot springs, and rivers carried acid brines with compositions that reflected close to congruent rock dissolution. The ratio between rock-forming elements and chloride in the central zone of the volcano-hydrothermal system has diminished over the past few years, reflecting increased water/rock ratios as a result of progressive rock dissolution. Magmatic activity in 2000 provided fresh rocks for the acid fluids, resulting in higher ratios between rock-forming elements and chloride in the fluids and enhanced Mg fluxes. The higher Mg fluxes started several weeks prior to the eruption. Model data on the crater lake and river element flux determinations indicate that Copahue volcano was hollowed out at a rate of about 20000 25000 m3/yr, but that void space was filled with about equal amounts of silica and liquid elemental sulfur. The extensive rock dissolution has weakened the internal volcanic structure, making flank collapse a volcanic hazard at Copahue.

Common processes at unique volcanoes – a volcanological conundrum

OpenAIRE

Katharine eCashman; Juliet eBiggs

2014-01-01

An emerging challenge in modern volcanology is the apparent contradiction between the perception that every volcano is unique, and classification systems based on commonalities among volcano morphology and eruptive style. On the one hand, detailed studies of individual volcanoes show that a single volcano often exhibits similar patterns of behavior over multiple eruptive episodes; this observation has led to the idea that each volcano has its own distinctive pattern of behavior (or “personali...

Ulcerative Proctitis

OpenAIRE

Whitlow, Charles B.

2004-01-01

Ulcerative proctitis is an idiopathic mucosal inflammatory disease involving only the rectum and is therefore an anatomically limited form of ulcerative colitis. Diagnosis is made based on clinical presentation, endoscopic appearance, and histopathology. Additionally, other etiologies of proctitis are excluded. The course of the disease is variable ranging from complete resolution to easily maintained remission to frequent relapses or refractory disease. Extension of inflammatory changes invo...

[Drug-induced oral ulcerations].

Science.gov (United States)

Madinier, I; Berry, N; Chichmanian, R M

2000-06-01

Different side effects of drugs have been described in the oral cavity, including oral ulcerations. Direct contact between drugs and oral mucosa may induce chemical burn or local hypersensitivity. Less frequently, these drug-induced oral ulcerations are part of a complex reaction with cutaneous or systemic manifestations. Sometimes, one or more oral ulcerations appear as the main side-effect of a drug, or exceptionally as solitary lesions. Solitary oral ulcerations usually appear after few weeks of treatment. In most of cases, these lesions resist to conventional treatments, with a rapid healing following the suppression of the responsible drug. This diagnosis is usually difficult, particularly with patients receiving multiple drug therapy. Besides, special attention must be paid to new drugs. Oral ulcerations following symptoms of burning mouth, metallic taste, dysgueusia or agueusia are strongly suggestive of a pharmacological origin. Most of the molecules able to induce solitary oral ulcerations are commonly prescribed in a) rheumatology: NSAI (diclofenac, flurbiprofen, indomethacin, naproxen), long-term rheumatoid arthritis therapy (azathioprine, methotrexate, penicillamine, gold compounds, tiopronin); b) cardiology: angiotensin-converting-enzyme inhibitors (captopril, enalapril), angiotensin 2-receptor antagonist (losartan), anti-angorous (nicorandil), c) psychiatry: antidepressants (fluoxetine, lithium), d) AIDS therapy (foscarnet, zalcitabine).

Review : Pressure Ulcer and Its treatment

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Bijan Khorasani

2004-10-01

Full Text Available Pressure ulcer is a signifcant problem in elderly and critically ill patients, causing pain, decreasing quality of life and leading to prolonged hospital stay. Treatment of pressure ulcer to improve health status is a cost-effective approach. So, preventing the ulcers will be economical. Pressure ulcer is considered as a damage or necrosis of skin and its layers, which happens when there is a considerable pressure over the tissues. If the capillary arterie's pressure reaches 70 mmHg (2 times more than the normal pressure pressure ulcer happens and depending on the depth of the ulcer, will be divided into 4 stages. The most important point for preventing the ulcers is reducing the pressure. Patients should be repositioned to relieve or minimize the tissue pressure. Considering the type of the ulcer, the necessary treatment (dressing, Antibiotic Therapy, debridement or surgery should be performed.

Prevalence of peptic ulcer in Iran: Systematic review and meta-analysis methods.

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Sayehmiri, Kourosh; Abangah, Ghobad; Kalvandi, Gholamreza; Tavan, Hamed; Aazami, Sanaz

2018-01-01

Peptic ulcer is a prevalent problem and symptoms include epigastria pain and heartburn. This study aimed at investigating the prevalence and causes of peptic ulcers in Iran using systematic review and meta-analysis. Eleven Iranian papers published from 2002 to 2016 are selected using valid keywords in the SID, Goggle scholar, PubMed and Elsevier databases. Results of studies pooled using random effects model in meta-analysis. The heterogeneity of the sample was checked using Q test and I 2 index. Total sample size in this study consist of 1335 individuals with peptic ulcer (121 samples per article). The prevalence of peptic ulcers was estimated 34% (95% CI= 0.25 - 0.43). The prevalence of peptic ulcers was 30% and 60% in woman and man respectively. The highest environmental factor (cigarette) has been addressed in 30% (95% CI= 0.23-0.37) of patients. The prevalence of Helicobacter pylori was estimated in 62% (95% CI= 0.49-0.75) of patients. The results of this study show that prevalence of peptic ulcers in Iran (34%) is higher that worldwide rate (6% to 15%). There was an increasing trend in the prevalence of peptic ulcer over a decade from 2002 to 2016.

Oropharynx Ulceration

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Lauren Sylwanowicz

2017-09-01

Full Text Available History of present illness: A 31-year-old male presented to the emergency department (ED with worsening constant left sided throat pain over the past four months. The patient reports that he was brushing his teeth when his dog jumped onto his back causing his toothbrush to puncture the back of his throat, resulting in immediate bleeding and discomfort. The bleeding subsided and the patient did not seek medical care. The pain radiated to his left ear and the back of the neck. He also noted a change in his voice. The day before presenting to the ED the patient noted subjective fevers, hemoptysis and drooling, which led him to seek medical care. Significant findings: The photograph demonstrates an area of ulcerative tissue at the left palatine tonsil without surrounding erythema or purulent drainage. The computed tomography (CT scan shows a large ulceration of the left soft palate and palatine tonsil (red arrow. There is no evidence of skull base osteomyelitis. There is suppurative lymphadenopathy with partial left jugular vein compression due to mass effect (yellow highlight. There is mild nasopharyngeal airway narrowing with architectural distortion (blue arrow, but no other evidence of airway obstruction. Discussion: The oral cavity is prone to trauma leading to the formation of superficial ulcerations. There are many causes of mechanical trauma, most commonly accidental biting. Chemical, electrical and thermal insults are also possibilities. Poor fitting dental devices and fractured or malformed teeth can also be etiologies.1 Traumatic ulcerations are most common in children given bruxism and thumb sucking. However, a broad differential must be considered including malignant and premalignant lesions, infections of the oral mucosa, aphthous ulcerations and autoimmune diseases.2, 3 Chronic ulcerations are associated with superimposed infection, but there has not been established an association of malignant transformation of the oral mucosa after

Pressure ulcers: development and psychometric evaluation of the attitude towards pressure ulcer prevention instrument (APuP).

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Beeckman, D; Defloor, T; Demarré, L; Van Hecke, A; Vanderwee, K

2010-11-01

Pressure ulcers continue to be a significant problem in hospitals, nursing homes and community care settings. Pressure ulcer incidence is widely accepted as an indicator for the quality of care. Negative attitudes towards pressure ulcer prevention may result in suboptimal preventive care. A reliable and valid instrument to assess attitudes towards pressure ulcer prevention is lacking. Development and psychometric evaluation of the Attitude towards Pressure ulcer Prevention instrument (APuP). Prospective psychometric instrument validation study. A literature review was performed to design the instrument. Content validity was evaluated by nine European pressure ulcer experts and five experts in psychometric instrument validation in a double Delphi procedure. A convenience sample of 258 nurses and 291 nursing students from Belgium and The Netherlands participated in order to evaluate construct validity and stability reliability of the instrument. The data were collected between February and May 2008. A factor analysis indicated the construct of a 13 item instrument in a five factor solution: (1) attitude towards personal competency to prevent pressure ulcers (three items); (2) attitude towards the priority of pressure ulcer prevention (three items); (3) attitude towards the impact of pressure ulcers (three items); (4) attitude towards personal responsibility in pressure ulcer prevention (two items); and (5) attitude towards confidence in the effectiveness of prevention (two items). This five factor solution accounted for 61.4% of the variance in responses related to attitudes towards pressure ulcer prevention. All items demonstrated factor loadings over 0.60. The instrument produced similar results during stability testing [ICC=0.88 (95% CI=0.84-0.91, Ppressure ulcer prevention in patient care, education, and research. In further research, the association between attitude, knowledge and clinical performance should be explored. Copyright 2010 Elsevier Ltd. All rights

Lycopene, Lutein and Zeaxanthin May Reduce Faecal Blood, Mucus and Pus but not Abdominal Pain in Individuals with Ulcerative Colitis.

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Głąbska, Dominika; Guzek, Dominika; Zakrzewska, Paulina; Włodarek, Dariusz; Lech, Gustaw

2016-09-30

The main symptom of ulcerative colitis is diarrhoea, which is often accompanied by painful tenesmus and faecal blood and mucus. It sometimes co-occurs with abdominal pain, fever, feeling of fatigue, loss of appetite and weight loss. Some dietary factors have been indicated as important in the treatment of ulcerative colitis. The aim of the study was to analyse the association between retinoid intake (total vitamin A, retinol, β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin) and ulcerative colitis symptoms (abdominal pain, faecal blood, faecal mucus, faecal pus) in individuals with ulcerative colitis in remission. Assessment of diet was based on self-reported data from each patient's dietary records taken over a period of three typical, random days (2 weekdays and 1 day of the weekend). A total of 56 individuals with ulcerative colitis in remission (19 males and 37 females) were recruited for the study. One in every four individuals with ulcerative colitis in remission was characterised as having inadequate vitamin A intake. Higher lycopene, lutein and zeaxanthin intakes in individuals with ulcerative colitis in remission were associated with lower faecal blood, mucus and pus but not with lower incidence of abdominal pain. Higher carotene intake in individuals with ulcerative colitis in remission may contribute to higher incidence of faecal mucus. Optimising intake of specific retinoids may enhance disease control in individuals with ulcerative colitis. Prospective studies, including patient reported and objective outcomes, are required to confirm this.

Pressure Ulcers Surveillance Report

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Zehra Esin Gencer

2015-04-01

Full Text Available Objective: Pressure ulcer is a chronic wound. It reduces the quality of life of the elderly and individuals with restricted range of motion. It prolongs hospital stay and increases the risk of complications. The cost is quite high. Preventive actions for the prevention of pressure ulcers should be developed. Planning protocols and standards of care are among the main targets. Material and Method: Research was conducted in one-year period between 2012 May and 2013 May on patients who were followed up in Akdeniz University Hospital clinics and intensive care unit with pressure ulcers. The research population consisted of 569 patients. Patient data were recorded in SPSS 16 for Windows program. Statistical analyzes were performed with retrospective methods. The demographic characteristics of patients with pressure ulcers were analyzed as frequency and descriptive statistics. Prevalence and incidence of one year were calculated. Results: Of the patients, 58% were males, 42% were females. Of the patients, 36% were in the age range of 61-80 years, and their average length of stay was 42,9 days. Of the patients, 70% were at stage 2 and 3. In 15% of patients pressure ulcers occurred on the first day of hospitalization. Pressure ulcers were developed between days 2 and 10 in 59% of the patients. Prevalence rate was 2.5%, the incidence was 1.9%, the prevalence rate was 5.9% in the intensive care unit. Conclusion: It is easier to prevent pressure ulcers than treating.

Penguin Bank: A Loa-Trend Hawaiian Volcano

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Xu, G.; Blichert-Toft, J.; Clague, D. A.; Cousens, B.; Frey, F. A.; Moore, J. G.

2007-12-01

Hawaiian volcanoes along the Hawaiian Ridge from Molokai Island in the northwest to the Big Island in the southeast, define two parallel trends of volcanoes known as the Loa and Kea spatial trends. In general, lavas erupted along these two trends have distinctive geochemical characteristics that have been used to define the spatial distribution of geochemical heterogeneities in the Hawaiian plume (e.g., Abouchami et al., 2005). These geochemical differences are well established for the volcanoes forming the Big Island. The longevity of the Loa- Kea geochemical differences can be assessed by studying East and West Molokai volcanoes and Penguin Bank which form a volcanic ridge perpendicular to the Loa and Kea spatial trends. Previously we showed that East Molokai volcano (~1.5 Ma) is exclusively Kea-like and that West Molokai volcano (~1.8 Ma) includes lavas that are both Loa- and Kea-like (Xu et al., 2005 and 2007).The submarine Penguin Bank (~2.2 Ma), probably an independent volcano constructed west of West Molokai volcano, should be dominantly Loa-like if the systematic Loa and Kea geochemical differences were present at ~2.2 Ma. We have studied 20 samples from Penguin Bank including both submarine and subaerially-erupted lavas recovered by dive and dredging. All lavas are tholeiitic basalt representing shield-stage lavas. Trace element ratios, such as Sr/Nb and Zr/Nb, and isotopic ratios of Sr and Nd clearly are Loa-like. On an ɛNd-ɛHf plot, Penguin Bank lavas fall within the field defined by Mauna Loa lavas. Pb isotopic data lie near the Loa-Kea boundary line defined by Abouchami et al. (2005). In conclusion, we find that from NE to SW, i.e., perpendicular to the Loa and Kea spatial trend, there is a shift from Kea-like East Molokai lavas to Loa-like Penguin Bank lavas with the intermediate West Molokai volcano having lavas with both Loa- and Kea-like geochemical features. Therefore, the Loa and Kea geochemical dichotomy exhibited by Big Island volcanoes

Etiopathogenetic principles and peptic ulcer disease classification

NARCIS (Netherlands)

Tytgat, G. N. J.

2011-01-01

Ulceration corresponds to tissue loss, breaching the muscularis mucosae. When ulcers develop in the acid-peptic environment of the gastroduodenum, they are traditionally called peptic ulcer (PUD). Ulcers never develop spontaneously in a healthy gastroduodenal mucosa. Ulceration is the ultimate

Bayesian estimation of magma supply, storage, and eruption rates using a multiphysical volcano model: Kīlauea Volcano, 2000-2012

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Anderson, Kyle R.; Poland, Michael P.

2016-08-01

Estimating rates of magma supply to the world's volcanoes remains one of the most fundamental aims of volcanology. Yet, supply rates can be difficult to estimate even at well-monitored volcanoes, in part because observations are noisy and are usually considered independently rather than as part of a holistic system. In this work we demonstrate a technique for probabilistically estimating time-variable rates of magma supply to a volcano through probabilistic constraint on storage and eruption rates. This approach utilizes Bayesian joint inversion of diverse datasets using predictions from a multiphysical volcano model, and independent prior information derived from previous geophysical, geochemical, and geological studies. The solution to the inverse problem takes the form of a probability density function which takes into account uncertainties in observations and prior information, and which we sample using a Markov chain Monte Carlo algorithm. Applying the technique to Kīlauea Volcano, we develop a model which relates magma flow rates with deformation of the volcano's surface, sulfur dioxide emission rates, lava flow field volumes, and composition of the volcano's basaltic magma. This model accounts for effects and processes mostly neglected in previous supply rate estimates at Kīlauea, including magma compressibility, loss of sulfur to the hydrothermal system, and potential magma storage in the volcano's deep rift zones. We jointly invert data and prior information to estimate rates of supply, storage, and eruption during three recent quasi-steady-state periods at the volcano. Results shed new light on the time-variability of magma supply to Kīlauea, which we find to have increased by 35-100% between 2001 and 2006 (from 0.11-0.17 to 0.18-0.28 km3/yr), before subsequently decreasing to 0.08-0.12 km3/yr by 2012. Changes in supply rate directly impact hazard at the volcano, and were largely responsible for an increase in eruption rate of 60-150% between 2001 and

Comparative study of quality of life and psychosocial characteristics in patients with psoriasis and leg ulcers.

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Kouris, Anargyros; Christodoulou, Christos; Efstathiou, Vasiliki; Tsatovidou, Revekka; Torlidi-Kordera, Evangelia; Zouridaki, Eftychia; Kontochristopoulos, George

2016-03-01

Psoriasis and leg ulcers have a marked impact on the patient's quality of life and represent a life-long burden for affected patients. The aim of this study is to compare the quality of life, anxiety and depression, self-esteem, and loneliness in patients with psoriasis and leg-ulcer patients. Eighty patients with leg ulcers, eighty patients with psoriasis, and eighty healthy controls were included in this study. The quality of life, depression and anxiety, loneliness of the patient, and self-esteem were assessed using the Dermatology Life Quality Index (DLQI), Hospital Anxiety and Depression Scale (HADS), the UCLA loneliness Scale (UCLA-Version 3), and the Rosenberg's Self-esteem Scale (RSES), respectively. The DLQI score among patients with psoriasis was 12.74 ± 4.89 and leg ulcer patients was 13.28 ± 2.57. The patients with psoriasis presented statistically significant higher anxiety (9.87 ± 4.56) than both leg ulcer patients (8.26 ± 2.82) and controls (6.45 ± 1.89), while leg ulcer patients also presented higher anxiety than controls. Regarding self-esteem, although there were no significant differences between the patients with psoriasis (15.25 ± 3.20) and the ones with leg ulcers (15.89 ± 2.93), they both presented statistically significant lower self-esteem scores than control group (18.53 ± 3.04). The patients with psoriasis presented statistically significant higher levels of loneliness and social isolation (46.18 ± 6.63) compared to leg ulcer patients (43.73 ± 5.68) than controls (42.49 ± 3.41). Psoriasis and leg ulcers are long-term skin diseases associated with significant impairment of the patient's quality of life, anxiety, and self-esteem, which are frequently under-recognized. © 2016 by the Wound Healing Society.

Multiphase modelling of mud volcanoes

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Colucci, Simone; de'Michieli Vitturi, Mattia; Clarke, Amanda B.

2015-04-01

Mud volcanism is a worldwide phenomenon, classically considered as the surface expression of piercement structures rooted in deep-seated over-pressured sediments in compressional tectonic settings. The release of fluids at mud volcanoes during repeated explosive episodes has been documented at numerous sites and the outflows resemble the eruption of basaltic magma. As magma, the material erupted from a mud volcano becomes more fluid and degasses while rising and decompressing. The release of those gases from mud volcanism is estimated to be a significant contributor both to fluid flux from the lithosphere to the hydrosphere, and to the atmospheric budget of some greenhouse gases, particularly methane. For these reasons, we simulated the fluid dynamics of mud volcanoes using a newly-developed compressible multiphase and multidimensional transient solver in the OpenFOAM framework, taking into account the multicomponent nature (CH4, CO2, H2O) of the fluid mixture, the gas exsolution during the ascent and the associated changes in the constitutive properties of the phases. The numerical model has been tested with conditions representative of the LUSI, a mud volcano that has been erupting since May 2006 in the densely populated Sidoarjo regency (East Java, Indonesia), forcing the evacuation of 40,000 people and destroying industry, farmland, and over 10,000 homes. The activity of LUSI mud volcano has been well documented (Vanderkluysen et al., 2014) and here we present a comparison of observed gas fluxes and mud extrusion rates with the outcomes of numerical simulations. Vanderkluysen, L.; Burton, M. R.; Clarke, A. B.; Hartnett, H. E. & Smekens, J.-F. Composition and flux of explosive gas release at LUSI mud volcano (East Java, Indonesia) Geochem. Geophys. Geosyst., Wiley-Blackwell, 2014, 15, 2932-2946

Efficient inversion of volcano deformation based on finite element models : An application to Kilauea volcano, Hawaii

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Charco, María; González, Pablo J.; Galán del Sastre, Pedro

2017-04-01

The Kilauea volcano (Hawaii, USA) is one of the most active volcanoes world-wide and therefore one of the better monitored volcanoes around the world. Its complex system provides a unique opportunity to investigate the dynamics of magma transport and supply. Geodetic techniques, as Interferometric Synthetic Aperture Radar (InSAR) are being extensively used to monitor ground deformation at volcanic areas. The quantitative interpretation of such surface ground deformation measurements using geodetic data requires both, physical modelling to simulate the observed signals and inversion approaches to estimate the magmatic source parameters. Here, we use synthetic aperture radar data from Sentinel-1 radar interferometry satellite mission to image volcano deformation sources during the inflation along Kilauea's Southwest Rift Zone in April-May 2015. We propose a Finite Element Model (FEM) for the calculation of Green functions in a mechanically heterogeneous domain. The key aspect of the methodology lies in applying the reciprocity relationship of the Green functions between the station and the source for efficient numerical inversions. The search for the best-fitting magmatic (point) source(s) is generally conducted for an array of 3-D locations extending below a predefined volume region. However, our approach allows to reduce the total number of Green functions to the number of the observation points by using the, above mentioned, reciprocity relationship. This new methodology is able to accurately represent magmatic processes using physical models capable of simulating volcano deformation in non-uniform material properties distribution domains, which eventually will lead to better description of the status of the volcano.

Geophysical Exploration on the Structure of Volcanoes: Two Case Histories

Energy Technology Data Exchange (ETDEWEB)

Furumoto, A. S.

1974-01-01

Geophysical methods of exploration were used to determine the internal structure of Koolau Volcano in Hawaii and of Rabaul Volcano in New Guinea. By use of gravity and seismic data the central vent or plug of Koolau Volcano was outlined. Magnetic data seem to indicate that the central plug is still above the Curie Point. If so, the amount of heat energy available is tremendous. As for Rabaul Volcano, it is located in a region characterized by numerous block faulting. The volcano is only a part of a large block that has subsided. Possible geothermal areas exist near the volcano but better potential areas may exist away from the volcano.

Growth and degradation of Hawaiian volcanoes: Chapter 3 in Characteristics of Hawaiian volcanoes

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Clague, David A.; Sherrod, David R.; Poland, Michael P.; Takahashi, T. Jane; Landowski, Claire M.

2014-01-01

The 19 known shield volcanoes of the main Hawaiian Islands—15 now emergent, 3 submerged, and 1 newly born and still submarine—lie at the southeast end of a long-lived hot spot chain. As the Pacific Plate of the Earth’s lithosphere moves slowly northwestward over the Hawaiian hot spot, volcanoes are successively born above it, evolve as they drift away from it, and eventually die and subside beneath the ocean surface.

Living with Volcanoes: Year Eleven Teaching Resource Unit.

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Le Heron, Kiri; Andrews, Jill; Hooks, Stacey; Larnder, Michele; Le Heron, Richard

2000-01-01

Presents a unit on volcanoes and experiences with volcanoes that helps students develop geography skills. Focuses on four volcanoes: (1) Rangitoto Island; (2) Lake Pupuke; (3) Mount Smart; and (4) One Tree Hill. Includes an answer sheet and resources to use with the unit. (CMK)

Effects of Volcanoes on the Natural Environment

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Mouginis-Mark, Peter J.

2005-01-01

The primary focus of this project has been on the development of techniques to study the thermal and gas output of volcanoes, and to explore our options for the collection of vegetation and soil data to enable us to assess the impact of this volcanic activity on the environment. We originally selected several volcanoes that have persistent gas emissions and/or magma production. The investigation took an integrated look at the environmental effects of a volcano. Through their persistent activity, basaltic volcanoes such as Kilauea (Hawaii) and Masaya (Nicaragua) contribute significant amounts of sulfur dioxide and other gases to the lower atmosphere. Although primarily local rather than regional in its impact, the continuous nature of these eruptions means that they can have a major impact on the troposphere for years to decades. Since mid-1986, Kilauea has emitted about 2,000 tonnes of sulfur dioxide per day, while between 1995 and 2000 Masaya has emotted about 1,000 to 1,500 tonnes per day (Duffel1 et al., 2001; Delmelle et al., 2002; Sutton and Elias, 2002). These emissions have a significant effect on the local environment. The volcanic smog ("vog" ) that is produced affects the health of local residents, impacts the local ecology via acid rain deposition and the generation of acidic soils, and is a concern to local air traffic due to reduced visibility. Much of the work that was conducted under this NASA project was focused on the development of field validation techniques of volcano degassing and thermal output that could then be correlated with satellite observations. In this way, we strove to develop methods by which not only our study volcanoes, but also volcanoes in general worldwide (Wright and Flynn, 2004; Wright et al., 2004). Thus volcanoes could be routinely monitored for their effects on the environment. The selected volcanoes were: Kilauea (Hawaii; 19.425 N, 155.292 W); Masaya (Nicaragua; 11.984 N, 86.161 W); and Pods (Costa Rica; 10.2OoN, 84.233 W).

Internet-accessible, near-real-time volcano monitoring data for geoscience education: the Volcanoes Exploration Project—Pu`u `O`o

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Poland, M. P.; Teasdale, R.; Kraft, K.

2010-12-01

Internet-accessible real- and near-real-time Earth science datasets are an important resource for geoscience education, but relatively few comprehensive datasets are available, and background information to aid interpretation is often lacking. In response to this need, the U.S. Geological Survey’s (USGS) Hawaiian Volcano Observatory, in collaboration with the National Aeronautics and Space Administration and the University of Hawai‘i, Mānoa, established the Volcanoes Exploration Project: Pu‘u ‘O‘o (VEPP). The VEPP Web site provides access, in near-real time, to geodetic, seismic, and geologic data from the Pu‘u ‘O‘o eruptive vent on Kilauea Volcano, Hawai‘i. On the VEPP Web site, a time series query tool provides a means of interacting with continuous geophysical data. In addition, results from episodic kinematic GPS campaigns and lava flow field maps are posted as data are collected, and archived Webcam images from Pu‘u ‘O‘o crater are available as a tool for examining visual changes in volcanic activity over time. A variety of background information on volcano surveillance and the history of the 1983-present Pu‘u ‘O‘o-Kupaianaha eruption puts the available monitoring data in context. The primary goal of the VEPP Web site is to take advantage of high visibility monitoring data that are seldom suitably well-organized to constitute an established educational resource. In doing so, the VEPP project provides a geoscience education resource that demonstrates the dynamic nature of volcanoes and promotes excitement about the process of scientific discovery through hands-on learning. To support use of the VEPP Web site, a week-long workshop was held at Kilauea Volcano in July 2010, which included 25 participants from the United States and Canada. The participants represented a diverse cross-section of higher learning, from community colleges to research universities, and included faculty who teach both large introductory non-major classes

Heel ulcers - Pressure ulcers or symptoms of peripheral arterial disease? An exploratory matched case control study.

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Twilley, Heidi; Jones, Sarahjane

2016-05-01

To investigate the relationship between pressure ulcers of the heel and peripheral arterial disease (PAD) and determine the feasibility of conducting a statistically powered matched case control study. Evidence indicates a relationship between chronic leg ulcers and vascular disease. The relationship between pressure ulcers of the heel and vascular disease is less well established. A matched case control study. Data were collected between March 2014 and January 2015. 15 patients identified as having a grade 2, 3 or 4 pressure ulcer of the heel were compared with 15 matched controls without pressure ulcers of the heel. The primary clinical outcome measure was the ankle brachial pressure index (ABPI), where an ABPI 1.3 was considered clinically indicative of PAD. The primary feasibility outcome measure was the rate of recruitment. Eighty seven patients were reported as having foot and heel ulcers; 36 of whom were identified as having pressure ulcers of the heel, 15 (42%) of whom were recruited to the study. Patients presenting with pressure ulcers of the heel were significantly more likely to simultaneously have previously undiagnosed PAD compared with age, gender and ethnicity matched controls without pressure ulcers of the heel (odds ratio: 11, 95% confidence interval 1.99-60.57). The formation of pressure ulcers of the heel could, in some patients, be related to the presence of PAD rather than a consequence of poor quality care. Healthcare professionals should assess the patient to exclude or confirm PAD. Copyright © 2016 Tissue Viability Society. Published by Elsevier Ltd. All rights reserved.

Enhancing Documentation of Pressure Ulcer Prevention Interventions: A Quality Improvement Strategy to Reduce Pressure Ulcers.

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Jacobson, Therese M; Thompson, Susan L; Halvorson, Anna M; Zeitler, Kristine

2016-01-01

Prevention of hospital-acquired pressure ulcers requires the implementation of evidence-based interventions. A quality improvement project was conducted to provide nurses with data on the frequency with which pressure ulcer prevention interventions were performed as measured by documentation. Documentation reports provided feedback to stakeholders, triggering reminders and reeducation. Intervention reports and modifications to the documentation system were effective both in increasing the documentation of pressure ulcer prevention interventions and in decreasing the number of avoidable hospital-acquired pressure ulcers.

Anesthetic keratopathy presenting as bilateral Mooren-like ulcers

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Khakshoor H

2012-10-01

Full Text Available Hamid Khakshoor,1 Majid Moshirfar,2 Rachel G Simpson,3 Hamid Gharaee,1 Amir H Vejdani,1 Steven M Christiansen,2 Jason N Edmonds,2 Nicholas L Behunin21Mashhad University of Medical Sciences, Department of Ophthalmology, Mashad, Iran; 2John A Moran Eye Center, University of Utah, Salt Lake City, UT, 3The University of Arizona College of Medicine, Phoenix, AZ, USAAbstract: This observational case report describes the development of bilateral Mooren-like ulcers in a patient with anesthetic keratopathy. A 42-year-old man with a recent history of minor eye trauma and pain self-treated with tetracaine eye drops presented with complaints of acutely worsening vision and severe pain bilaterally. His visual acuity at presentation was limited to hand motion. Slit-lamp examination revealed bilateral epithelial defects at the center of the cornea, and an area of stromal infiltration and thinning with an undermining leading edge resembling a Mooren's ulcer in both eyes. Corneal haze and hypopyon were visible. Anesthetic use was halted immediately and the patient was started on prednisolone and mycophenolate mofetil (Cellcept®, after which visual acuity gradually improved and pain decreased. Despite improvement of symptoms, residual epithelial defects remained, and the patient was ultimately treated with keratoplasty for recovery of vision. We suggest that anesthetic keratopathy should be included in the differential diagnosis for any patient presenting with ring-shaped stromal infiltrates or nonhealing epithelial defects.Keywords: anesthetic abuse, corneal damage, corneal ulceration

Petrologic insights into basaltic volcanism at historically active Hawaiian volcanoes: Chapter 6 in Characteristics of Hawaiian volcanoes

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Helz, Rosalind L.; Clague, David A.; Sisson, Thomas W.; Thornber, Carl R.; Poland, Michael P.; Takahashi, T. Jane; Landowski, Claire M.

2014-01-01

Study of the petrology of Hawaiian volcanoes, in particular the historically active volcanoes on the Island of Hawai‘i, has long been of worldwide scientific interest. When Dr. Thomas A. Jaggar, Jr., established the Hawaiian Volcano Observatory (HVO) in 1912, detailed observations on basaltic activity at Kīlauea and Mauna Loa volcanoes increased dramatically. The period from 1912 to 1958 saw a gradual increase in the collection and analysis of samples from the historical eruptions of Kīlauea and Mauna Loa and development of the concepts needed to evaluate them. In a classic 1955 paper, Howard Powers introduced the concepts of magnesia variation diagrams, to display basaltic compositions, and olivine-control lines, to distinguish between possibly comagmatic and clearly distinct basaltic lineages. In particular, he and others recognized that Kīlauea and Mauna Loa basalts must have different sources.

Peptic Ulcers in Fukushima Prefecture Related to the Great East Japan Earthquake, Tsunami and Nuclear Accident

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Hikichi, Takuto; Sato, Masaki; Watanabe, Ko; Nakamura, Jun; Kikuchi, Hitomi; Ejiri, Yutaka; Ishihata, Ryoichi; Irisawa, Atsushi; Takahashi, Yuta; Saito, Hironobu; Takagi, Tadayuki; Suzuki, Rei; Sugimoto, Mitsuru; Konno, Naoki; Waragai, Yuichi; Asama, Hiroyuki; Takasumi, Mika; Sato, Yuki; Ohira, Hiromasa; Obara, Katsutoshi

2017-01-01

Objective Due to the Great East Japan Earthquake, which occurred in March 2011, many residents of Fukushima Prefecture were affected by a radiation accident in addition to suffering loss or damage from the earthquake and the subsequent tsunami. The aim of this study was to evaluate the actual condition of patients with peptic ulcers related to the disaster. Methods Patients with peptic ulcers at six hospitals in three different regions of Fukushima Prefecture during the two months following the disaster and the corresponding period of the year before and the year after the disaster were enrolled in this study. Changes by period and region in the number of esophagogastroduodenoscopy (EGD) examinations and the number of peptic ulcer patients were evaluated as the primary endpoints. Changes in the frequencies of hemorrhagic ulcers were evaluated by period and by region as secondary endpoints. Results The numbers of EGDs and peptic ulcer cases compared to the previous year decreased in 2011 and then increased in 2012. However, the ratio of hemorrhagic ulcers to peptic ulcers was higher in 2011 (51.9%) than in 2010 (38.1%) and 2012 (31.1%), and the 2011 hemorrhagic ulcer ratio was the highest at 63.6% in the coastal area. Regarding bleeding cases during 2011, the rate at 1 month after the disaster (64.1%) was higher than the rate at 2 months after the disaster (40.5%) (p=0.033). Conclusion The number of patients with peptic ulcers did not increase immediately following the disaster in Fukushima Prefecture. However, the rate of bleeding patients increased soon after the disaster, especially in the coastal area. PMID:29269647

Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer.

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Junichiro En

2017-08-01

Full Text Available Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to elucidate the mechanism of this nerve damage, we tested and compared the cytotoxic effect of synthetic mycolactone A/B on cultured Schwann cells, fibroblasts and macrophages. Mycolactone induced much higher cell death and apoptosis in Schwann cell line SW10 than in fibroblast line L929. These results suggest that mycolactone is a key substance in the production of nerve damage of Buruli ulcer.

Gastric emptying abnormal in duodenal ulcer

Energy Technology Data Exchange (ETDEWEB)

Holt, S.; Heading, R.C.; Taylor, T.V.; Forrest, J.A.; Tothill, P.

1986-07-01

To investigate the possibility that an abnormality of gastric emptying exists in duodenal ulcer and to determine if such an abnormality persists after ulcer healing, scintigraphic gastric emptying measurements were undertaken in 16 duodenal ulcer patients before, during, and after therapy with cimetidine; in 12 patients with pernicious anemia, and in 12 control subjects. No difference was detected in the rate or pattern of gastric emptying in duodenal ulcer patients before and after ulcer healing with cimetidine compared with controls, but emptying of the solid component of the test meal was more rapid during treatment with the drug. Comparison of emptying patterns obtained in duodenal ulcer subjects during and after cimetidine treatment with those obtained in pernicious anemia patients and controls revealed a similar relationship that was characterized by a tendency for reduction in the normal differentiation between the emptying of solid and liquid from the stomach. The similarity in emptying patterns in these groups of subjects suggests that gastric emptying of solids may be influenced by changes in the volume of gastric secretion. The failure to detect an abnormality of gastric emptying in duodenal ulcer subjects before and after ulcer healing calls into question the widespread belief that abnormally rapid gastric emptying is a feature with pathogenetic significance in duodenal ulcer disease.

Gastric emptying abnormal in duodenal ulcer

International Nuclear Information System (INIS)

Holt, S.; Heading, R.C.; Taylor, T.V.; Forrest, J.A.; Tothill, P.

1986-01-01

To investigate the possibility that an abnormality of gastric emptying exists in duodenal ulcer and to determine if such an abnormality persists after ulcer healing, scintigraphic gastric emptying measurements were undertaken in 16 duodenal ulcer patients before, during, and after therapy with cimetidine; in 12 patients with pernicious anemia, and in 12 control subjects. No difference was detected in the rate or pattern of gastric emptying in duodenal ulcer patients before and after ulcer healing with cimetidine compared with controls, but emptying of the solid component of the test meal was more rapid during treatment with the drug. Comparison of emptying patterns obtained in duodenal ulcer subjects during and after cimetidine treatment with those obtained in pernicious anemia patients and controls revealed a similar relationship that was characterized by a tendency for reduction in the normal differentiation between the emptying of solid and liquid from the stomach. The similarity in emptying patterns in these groups of subjects suggests that gastric emptying of solids may be influenced by changes in the volume of gastric secretion. The failure to detect an abnormality of gastric emptying in duodenal ulcer subjects before and after ulcer healing calls into question the widespread belief that abnormally rapid gastric emptying is a feature with pathogenetic significance in duodenal ulcer disease

Lycopene, Lutein and Zeaxanthin May Reduce Faecal Blood, Mucus and Pus but not Abdominal Pain in Individuals with Ulcerative Colitis

Science.gov (United States)

Głąbska, Dominika; Guzek, Dominika; Zakrzewska, Paulina; Włodarek, Dariusz; Lech, Gustaw

2016-01-01

Background: The main symptom of ulcerative colitis is diarrhoea, which is often accompanied by painful tenesmus and faecal blood and mucus. It sometimes co-occurs with abdominal pain, fever, feeling of fatigue, loss of appetite and weight loss. Some dietary factors have been indicated as important in the treatment of ulcerative colitis. The aim of the study was to analyse the association between retinoid intake (total vitamin A, retinol, β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin) and ulcerative colitis symptoms (abdominal pain, faecal blood, faecal mucus, faecal pus) in individuals with ulcerative colitis in remission. Methods: Assessment of diet was based on self-reported data from each patient’s dietary records taken over a period of three typical, random days (2 weekdays and 1 day of the weekend). Results: A total of 56 individuals with ulcerative colitis in remission (19 males and 37 females) were recruited for the study. One in every four individuals with ulcerative colitis in remission was characterised as having inadequate vitamin A intake. Higher lycopene, lutein and zeaxanthin intakes in individuals with ulcerative colitis in remission were associated with lower faecal blood, mucus and pus but not with lower incidence of abdominal pain. Higher carotene intake in individuals with ulcerative colitis in remission may contribute to higher incidence of faecal mucus. Conclusions: Optimising intake of specific retinoids may enhance disease control in individuals with ulcerative colitis. Prospective studies, including patient reported and objective outcomes, are required to confirm this. PMID:27706028

Management of parastomal ulcers

Institute of Scientific and Technical Information of China (English)

Heather Yeo; Farshad Abir; Walter E Longo

2006-01-01

Management of surgically placed ostomies is an important aspect of any general surgical or colon and rectal surgery practice. Complications with surgically placed ostomies are common and their causes are multifactorial. Parastomal ulceration, although rare, is a particularly difficult management problem. We conducted a literature search using MD Consult, Science Direct,OVID, Medline, and Cochrane Databases to review the causes and management options of parastomal ulceration. Both the etiology and treatments are varied.Different physicians and ostomy specialists have used a large array of methods to manage parastomal ulcers;these including local wound care; steroid creams;systemic steroids; and, when conservative measures fail, surgery. Most patients with parastomal ulcers who do not have associated IBD or peristomal pyoderma gangrenosum (PPG) often respond quickly to local wound care and conservative management. Patients with PPG,IBD,or other systemic causes of their ulceration need both systemic and local care and are more likely to need long term treatment and possibly surgical revision of the ostomy. The treatment is complicated, but improved with the help of ostomy specialists.

[Evaluation of the cost of treating pressure ulcers in hospitalized patients using industrialized dressings].

Science.gov (United States)

Lima, Angela Cristina Beck; Guerra, Diana Mendonça

2011-01-01

This work evaluated wound dresses used in the Neurosurgery Department of Restauração Hospital: polyurethane, hydrogel and activated carbon wound dresses and hydrogel with alginate used for pressure ulcer care. This work aimed to identify a critical factor that increases demand and cost of wound dresses. The evaluation conducted at the Neurosurgery Department identified individuals at risk of pressure ulcer development. Sixty-two patients were evaluated and the prevalence of pressure ulcer was 22.6% according to the Braden scale. Comparative evaluation between patients that didn't receive preventive measures and others that received, showed that the average daily cost of hospitalization for the first group was 45% higher than the mean for the second group. The Wilcoxon-Mann-Withiney test compared the population at risk to develop pressure ulcer and population at low risk showing that the evaluation of Braden Scale scores between the groups presents statistically significant differences and confidence limits of 95%. Pressure ulcer is a key quality indicator in health services.It is possible to reduce costs and offer higher quality public health services by implementing a training program of nursing staff using a preventive measure protocol based on a test to evaluate risk as Braden Scale.

The critical role of volcano monitoring in risk reduction

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R. I. Tilling

2008-01-01

Full Text Available Data from volcano-monitoring studies constitute the only scientifically valid basis for short-term forecasts of a future eruption, or of possible changes during an ongoing eruption. Thus, in any effective hazards-mitigation program, a basic strategy in reducing volcano risk is the initiation or augmentation of volcano monitoring at historically active volcanoes and also at geologically young, but presently dormant, volcanoes with potential for reactivation. Beginning with the 1980s, substantial progress in volcano-monitoring techniques and networks – ground-based as well space-based – has been achieved. Although some geochemical monitoring techniques (e.g., remote measurement of volcanic gas emissions are being increasingly applied and show considerable promise, seismic and geodetic methods to date remain the techniques of choice and are the most widely used. Availability of comprehensive volcano-monitoring data was a decisive factor in the successful scientific and governmental responses to the reawakening of Mount St. elens (Washington, USA in 1980 and, more recently, to the powerful explosive eruptions at Mount Pinatubo (Luzon, Philippines in 1991. However, even with the ever-improving state-of-the-art in volcano monitoring and predictive capability, the Mount St. Helens and Pinatubo case histories unfortunately still represent the exceptions, rather than the rule, in successfully forecasting the most likely outcome of volcano unrest.

Lahar hazards at Mombacho Volcano, Nicaragua

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Vallance, J.W.; Schilling, S.P.; Devoli, G.

2001-01-01

Mombacho volcano, at 1,350 meters, is situated on the shores of Lake Nicaragua and about 12 kilometers south of Granada, a city of about 90,000 inhabitants. Many more people live a few kilometers southeast of Granada in 'las Isletas de Granada and the nearby 'Peninsula de Aseses. These areas are formed of deposits of a large debris avalanche (a fast moving avalanche of rock and debris) from Mombacho. Several smaller towns with population, in the range of 5,000 to 12,000 inhabitants are to the northwest and the southwest of Mombacho volcano. Though the volcano has apparently not been active in historical time, or about the last 500 years, it has the potential to produce landslides and debris flows (watery flows of mud, rock, and debris -- also known as lahars when they occur on a volcano) that could inundate these nearby populated areas. -- Vallance, et.al., 2001

Bayesian estimation of magma supply, storage, and eruption rates using a multiphysical volcano model: Kīlauea Volcano, 2000–2012

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Anderson, Kyle R.; Poland, Michael

2016-01-01

Estimating rates of magma supply to the world's volcanoes remains one of the most fundamental aims of volcanology. Yet, supply rates can be difficult to estimate even at well-monitored volcanoes, in part because observations are noisy and are usually considered independently rather than as part of a holistic system. In this work we demonstrate a technique for probabilistically estimating time-variable rates of magma supply to a volcano through probabilistic constraint on storage and eruption rates. This approach utilizes Bayesian joint inversion of diverse datasets using predictions from a multiphysical volcano model, and independent prior information derived from previous geophysical, geochemical, and geological studies. The solution to the inverse problem takes the form of a probability density function which takes into account uncertainties in observations and prior information, and which we sample using a Markov chain Monte Carlo algorithm. Applying the technique to Kīlauea Volcano, we develop a model which relates magma flow rates with deformation of the volcano's surface, sulfur dioxide emission rates, lava flow field volumes, and composition of the volcano's basaltic magma. This model accounts for effects and processes mostly neglected in previous supply rate estimates at Kīlauea, including magma compressibility, loss of sulfur to the hydrothermal system, and potential magma storage in the volcano's deep rift zones. We jointly invert data and prior information to estimate rates of supply, storage, and eruption during three recent quasi-steady-state periods at the volcano. Results shed new light on the time-variability of magma supply to Kīlauea, which we find to have increased by 35–100% between 2001 and 2006 (from 0.11–0.17 to 0.18–0.28 km3/yr), before subsequently decreasing to 0.08–0.12 km3/yr by 2012. Changes in supply rate directly impact hazard at the volcano, and were largely responsible for an increase in eruption rate of 60–150% between

Depression and incident diabetic foot ulcers: a prospective cohort study

Science.gov (United States)

Williams, Lisa H.; Rutter, Carolyn M.; Katon, Wayne J.; Reiber, Gayle E.; Ciechanowski, Paul; Heckbert, Susan R.; Lin, Elizabeth H.B.; Ludman, Evette J.; Oliver, Malia M.; Young, Bessie A.; Von Korff, Michael

2010-01-01

Objective To test whether depression is associated with an increased risk of incident diabetic foot ulcers. Methods The Pathways Epidemiologic Study is a population-based prospective cohort study of 4839 patients with diabetes in 2000–2007. The present analysis included 3474 adults with type 2 diabetes and no prior diabetic foot ulcers or amputations. Mean follow-up was 4.1 years. Major and minor depression assessed by the Patient Health Questionnaire-9 (PHQ-9) were the exposures of interest. The outcome of interest was incident diabetic foot ulcers. We computed the hazard ratio (HR) and 95% CI for incident diabetic foot ulcers, comparing patients with major and minor depression to those without depression and adjusting for sociodemographic characteristics, medical comorbidity, glycosylated hemoglobin (HbA1c), diabetes duration, insulin use, number of diabetes complications, body mass index, smoking status, and foot self-care. Sensitivity analyses also adjusted for peripheral neuropathy and peripheral arterial disease as defined by diagnosis codes. Results Compared to patients without depression, patients with major depression by PHQ-9 had a two-fold increase in the risk of incident diabetic foot ulcers (adjusted HR 2.00, 95% CI: 1.24, 3.25). There was no statistically significant association between minor depression by PHQ-9 and incident diabetic foot ulcers (adjusted HR 1.37, 95% CI: 0.77, 2.44). Conclusion Major depression by PHQ-9 is associated with a two-fold higher risk of incident diabetic foot ulcers. Future studies of this association should include better measures of peripheral neuropathy and peripheral arterial disease, which are possible confounders and/or mediators. PMID:20670730

The Implications of Endoscopic Ulcer in Early Gastric Cancer: Can We Predict Clinical Behaviors from Endoscopy?

Directory of Open Access Journals (Sweden)

Yoo Jin Lee

Full Text Available The presence of ulcer in early gastric cancer (EGC is important for the feasibility of endoscopic resection, only a few studies have examined the clinicopathological implications of endoscopic ulcer in EGC.To determine the role of endoscopic ulcer as a predictor of clinical behaviors in EGC.Data of 3,270 patients with EGC who underwent surgery between January 2005 and December 2012 were reviewed. Clinicopathological characteristics were analyzed in relation to the presence and stage of ulcer in EGC. Based on endoscopic findings, the stage of ulcer was categorized as active, healing, or scar. Logistic regression analysis was performed to analyze factors associated with lymph node metastasis (LNM.2,343 (71.7% patients had endoscopic findings of ulceration in EGC. Submucosal (SM invasion, LNM, lymphovascular invasion (LVI, perineural invasion, and undifferentiated-type histology were significantly higher in ulcerative than non-ulcerative EGC. Comparison across different stages of ulcer revealed that SM invasion, LNM, and LVI were significantly associated with the active stage, and that these features exhibited significant stage-based differences, being most common at the active stage, and least common at the scar stage. The presence of endoscopic ulcer and active status of the ulcer were identified as independent risk factors for LNM.Ulcerative EGC detected by endoscopy exhibited more aggressive behaviors than non-ulcerative EGC. Additionally, the endoscopic stage of ulcer may predict the clinicopathological behaviors of EGC. Therefore, the appearance of ulcers should be carefully evaluated to determine an adequate treatment strategy for EGC.

Eruption style at Kīlauea Volcano in Hawai‘i linked to primary melt composition

Science.gov (United States)

Sides. I.R.,; Edmonds, M.; Maclennan, J.; Swanson, Don; Houghton, Bruce F.

2014-01-01

Explosive eruptions at basaltic volcanoes have been linked to gas segregation from magmas at shallow depths in the crust. The composition of primary melts formed at greater depths was thought to have little influence on eruptive style. Ocean island basaltic volcanoes are the product of melting of a geochemically heterogeneous mantle plume and are expected to give rise to heterogeneous primary melts. This range in primary melt composition, particularly with respect to the volatile components, will profoundly influence magma buoyancy, storage and eruption style. Here we analyse the geochemistry of a suite of melt inclusions from 25 historical eruptions at the ocean island volcano of Kīlauea, Hawai‘i, over the past 600 years. We find that more explosive styles of eruption at Kīlauea Volcano are associated statistically with more geochemically enriched primary melts that have higher volatile concentrations. These enriched melts ascend faster and retain their primary nature, undergoing little interaction with the magma reservoir at the volcano’s summit. We conclude that the eruption style and magma-supply rate at Kīlauea are fundamentally linked to the geochemistry of the primary melts formed deep below the volcano. Magmas might therefore be predisposed towards explosivity right at the point of formation in their mantle source region.

38 CFR 4.110 - Ulcers.

Science.gov (United States)

2010-07-01

... DISABILITIES Disability Ratings The Digestive System § 4.110 Ulcers. Experience has shown that the term “peptic ulcer” is not sufficiently specific for rating purposes. Manifest differences in ulcers of the stomach... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Ulcers. 4.110 Section 4...

Leg ulcers in older people: a national study addressing variation in diagnosis, pain and sleep disturbance.

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Hellström, Amanda; Nilsson, Camilla; Nilsson, Annina; Fagerström, Cecilia

2016-01-21

Leg ulcers commonly emerge as a symptom of other comorbidities, often in older people. As a consequence of the ulcer, pain and sleep disturbances might occur. Due to the complex illness, the responsibility of treatment is unclear between health caregivers. The interaction between ulcer type, sleep and pain has not previously been investigated. This study aimed to explore pain in older men and women (65 years and older) with different diagnoses of leg ulcers and to investigate the associations of sleep disturbances and pain in people with leg ulcer diagnosis. The study used a cross-sectional design and data from the Swedish Registry of Ulcer Treatment, collected between May 2009 and December 2013. One thousand and eight hundred and twenty four people were included, and 62.9% were women. The mean age was 83.4 years (SD 8.8). For the analyses, the chi-square test, Mann-Whitney U-test, t-test, one-way ANOVA and logistic regression was performed. Pain was measured by the Numeric Rating Scale (NRS), and sleep disturbances was assessed dichotomously. We found the prevalence of pain intensity ≥ 5 on the NRS to be 34.8% in those reporting pain. Additionally, the pain intensity was associated with the number of ulcers (p = 0.003). Sleep disturbances were associated with pain (p pain and scored higher on the NRS, no significant gender difference in sleep disturbances was found (p = 0.606). The mean NRS scores did not differ significantly between the ulcer types; however, arterial and venous-arterial ulcers increased the risk of sleep disturbances, as did higher pain scores. The majority of the participants were of advanced age (>80 years) and frequently suffered from pain and sleep disturbances. Further research is needed regarding pain, sleep and wound healing in the oldest old with leg ulcers. Ulcer pain sometimes appears to receive less attention in ulcer management, as do sleep disturbances, implying that individual needs might not be satisfactorily met

Laparoscopic pyloroplasty for perforated peptic ulcer.

Science.gov (United States)

Grišin, Edvard; Mikalauskas, Saulius; Poškus, Tomas; Jotautas, Valdemaras; Strupas, Kęstutis

2017-09-01

Peptic ulcer is a common disease affecting millions of people every year. Despite improved understanding and treatment of the disease, the number of patients admitted with duodenal peptic ulcer perforation has not decreased. Deaths from peptic ulcer disease overcome other common emergency situations. Laparoscopic repair of the perforated peptic ulcer (PPU) is the gold standard approach for simple perforation. However, in patients with large perforated chronic ulcers laparotomy with pyloroplasty is the standard treatment. It is generally accepted to perform open surgery in PPU emergencies because of the greater knowledge and experience gathered over the past decades and less potential harm for the patient or surgical complications. We present a case of successful laparoscopic pyloroplasty of a perforated duodenal ulcer with stenosis.

Leg ulcers due to hyperhomocysteinemia

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Krupa Shankar D

2006-01-01

Full Text Available Chronic leg ulcers are rare in young adults and generally indicate a vascular cause. We report a case of a 26-year-old man with leg ulcers of eight months duration. Doppler study indicated venous incompetence and a postphlebitic limb. However, as the distribution and number of ulcers was not consistent with stasis alone and no features of collagen vascular disease were noted, a hyperviscosity state was considered and confirmed with significantly elevated homocysteine level in the serum. Administration of vitamins B1, B2, B6 and B12, trimethyl-glycine, mecobalamine, folic acid and povidone iodine dressings with culture-directed antibiotic therapy led to a satisfactory healing of ulcers over a period of one month. Hyperhomocysteinemia must be considered in the differential diagnosis of leg ulcers in young individuals.

How Do Volcanoes Affect Human Life? Integrated Unit.

Science.gov (United States)

Dayton, Rebecca; Edwards, Carrie; Sisler, Michelle

This packet contains a unit on teaching about volcanoes. The following question is addressed: How do volcanoes affect human life? The unit covers approximately three weeks of instruction and strives to present volcanoes in an holistic form. The five subject areas of art, language arts, mathematics, science, and social studies are integrated into…

The Powell Volcano Remote Sensing Working Group Overview

Science.gov (United States)

Reath, K.; Pritchard, M. E.; Poland, M. P.; Wessels, R. L.; Biggs, J.; Carn, S. A.; Griswold, J. P.; Ogburn, S. E.; Wright, R.; Lundgren, P.; Andrews, B. J.; Wauthier, C.; Lopez, T.; Vaughan, R. G.; Rumpf, M. E.; Webley, P. W.; Loughlin, S.; Meyer, F. J.; Pavolonis, M. J.

2017-12-01

Hazards from volcanic eruptions pose risks to the lives and livelihood of local populations, with potential global impacts to businesses, agriculture, and air travel. The 2015 Global Assessment of Risk report notes that 800 million people are estimated to live within 100 km of 1400 subaerial volcanoes identified as having eruption potential. However, only 55% of these volcanoes have any type of ground-based monitoring. The only methods currently available to monitor these unmonitored volcanoes are space-based systems that provide a global view. However, with the explosion of data techniques and sensors currently available, taking full advantage of these resources can be challenging. The USGS Powell Center Volcano Remote Sensing Working Group is working with many partners to optimize satellite resources for global detection of volcanic unrest and assessment of potential eruption hazards. In this presentation we will describe our efforts to: 1) work with space agencies to target acquisitions from the international constellation of satellites to collect the right types of data at volcanoes with forecasting potential; 2) collaborate with the scientific community to develop databases of remotely acquired observations of volcanic thermal, degassing, and deformation signals to facilitate change detection and assess how these changes are (or are not) related to eruption; and 3) improve usage of satellite observations by end users at volcano observatories that report to their respective governments. Currently, the group has developed time series plots for 48 Latin American volcanoes that incorporate variations in thermal, degassing, and deformation readings over time. These are compared against eruption timing and ground-based data provided by the Smithsonian Institute Global Volcanism Program. Distinct patterns in unrest and eruption are observed at different volcanoes, illustrating the difficulty in developing generalizations, but highlighting the power of remote sensing

Correlating the electrification of volcanic plumes with ashfall textures at Sakurajima Volcano, Japan

Science.gov (United States)

Smith, Cassandra M.; Van Eaton, Alexa R.; Charbonnier, Sylvain; McNutt, Stephen R.; Behnke, Sonja A.; Thomas, Ronald J.; Edens, Harald E.; Thompson, Glenn

2018-06-01

Volcanic lightning detection has become a useful resource for monitoring remote, under-instrumented volcanoes. Previous studies have shown that the behavior of volcanic plume electrification responds to changes in the eruptive processes and products. However, there has not yet been a study to quantify the links between ash textures and plume electrification during an actively monitored eruption. In this study, we examine a sequence of vulcanian eruptions from Sakurajima Volcano in Japan to compare ash textural properties (grain size, shape, componentry, and groundmass crystallinity) to plume electrification using a lightning mapping array and other monitoring data. We show that the presence of the continual radio frequency (CRF) signal is more likely to occur during eruptions that produce large seismic amplitudes (>7 μm) and glass-rich volcanic ash with more equant particle shapes. We show that CRF is generated during energetic, impulsive eruptions, where charge buildup is enhanced by secondary fragmentation (milling) as particles travel out of the conduit and into the gas-thrust region of the plume. We show that the CRF signal is influenced by a different electrification process than later volcanic lightning. By using volcanic CRF and lightning to better understand the eruptive event and its products these key observations will help the monitoring community better utilize volcanic electrification as a method for monitoring and understanding ongoing explosive eruptions.

The VCU Pressure Ulcer Summit: Collaboration to Operationalize Hospital-Acquired Pressure Ulcer Prevention Best Practice Recommendations.

Science.gov (United States)

Brindle, C Tod; Creehan, Sue; Black, Joyce; Zimmermann, Deb

2015-01-01

This executive summary reports outcomes of an interprofessional collaboration between experts in pressure ulcer prevention, bedside clinicians, regulatory agencies, quality improvement, informatics experts, and professional nursing organizations. The goal of the collaboration was to develop a framework to assist facilities to operationalize best practice recommendations to sustain organizational culture change in hospital-acquired pressure ulcer prevention, to develop a hospital-acquired pressure ulcer severity score, and to address topics related to the unavoidable pressure ulcer.

Volcano hazards in the San Salvador region, El Salvador

Science.gov (United States)

Major, J.J.; Schilling, S.P.; Sofield, D.J.; Escobar, C.D.; Pullinger, C.R.

2001-01-01

San Salvador volcano is one of many volcanoes along the volcanic arc in El Salvador (figure 1). This volcano, having a volume of about 110 cubic kilometers, towers above San Salvador, the country’s capital and largest city. The city has a population of approximately 2 million, and a population density of about 2100 people per square kilometer. The city of San Salvador and other communities have gradually encroached onto the lower flanks of the volcano, increasing the risk that even small events may have serious societal consequences. San Salvador volcano has not erupted for more than 80 years, but it has a long history of repeated, and sometimes violent, eruptions. The volcano is composed of remnants of multiple eruptive centers, and these remnants are commonly referred to by several names. The central part of the volcano, which contains a large circular crater, is known as El Boquerón, and it rises to an altitude of about 1890 meters. El Picacho, the prominent peak of highest elevation (1960 meters altitude) to the northeast of the crater, and El Jabali, the peak to the northwest of the crater, represent remnants of an older, larger edifice. The volcano has erupted several times during the past 70,000 years from vents central to the volcano as well as from smaller vents and fissures on its flanks [1] (numerals in brackets refer to end notes in the report). In addition, several small cinder cones and explosion craters are located within 10 kilometers of the volcano. Since about 1200 A.D., eruptions have occurred almost exclusively along, or a few kilometers beyond, the northwest flank of the volcano, and have consisted primarily of small explosions and emplacement of lava flows. However, San Salvador volcano has erupted violently and explosively in the past, even as recently as 800 years ago. When such eruptions occur again, substantial population and infrastructure will be at risk. Volcanic eruptions are not the only events that present a risk to local

Geoflicks Reviewed--Films about Hawaiian Volcanoes.

Science.gov (United States)

Bykerk-Kauffman, Ann

1994-01-01

Reviews 11 films on volcanic eruptions in the United States. Films are given a one- to five-star rating and the film's year, length, source and price are listed. Top films include "Inside Hawaiian Volcanoes" and "Kilauea: Close up of an Active Volcano." (AIM)

Marjolin's Ulcers: A Review

African Journals Online (AJOL)

Alasia Datonye

remains a feature of this pathology even in recent times. Prognosis ... marjolin's ulcers such as chronic leg ulcers and poorly managed burns ... the distribution of the disease. ..... Squamous cell carcinoma complicating chronic venous leg.

Selective binding of sucralfate to endoscopic mucosal resection-induced gastric ulcer: evaluation of aluminium adherence.

Science.gov (United States)

Itoh, T; Kusaka, K; Kawaura, K; Kashimura, K; Yamakawa, J; Takahashi, T; Kanda, T

2004-01-01

We evaluated the effect of sucralfate in patients with early gastric cancer in endoscopic mucosal resection (EMR)-induced gastric ulcers, and in rats with acetic acid-induced ulcers, by measuring concentrations of aluminium adhering to mucosal lesions. Twenty-two patients who underwent EMR received sucralfate with or without ranitidine and were examined endoscopically after 1 week, 2 weeks and 3 weeks. Gastric juice pH and concentration of aluminium in samples of ulcerated and normal mucosa were measured at various time-points. Good ulcer healing was observed in all patients. Significantly higher concentrations of aluminium were found in ulcerated tissue compared with normal mucosa. This selective binding of sucralfate was even found 12 h after drug administration and was confirmed in acetic acid-induced ulcers in 40 rats. Neutral rather than acid gastric juice was observed up to 12 h after the administration of sucralfate alone. These results suggest that sucralfate with or without ranitidine may contribute to the healing of EMR-induced ulcers by selectively binding to lesions.

Plantar pressure in diabetic peripheral neuropathy patients with active foot ulceration, previous ulceration and no history of ulceration: a meta-analysis of observational studies.

Science.gov (United States)

Fernando, Malindu Eranga; Crowther, Robert George; Pappas, Elise; Lazzarini, Peter Anthony; Cunningham, Margaret; Sangla, Kunwarjit Singh; Buttner, Petra; Golledge, Jonathan

2014-01-01

Elevated dynamic plantar pressures are a consistent finding in diabetes patients with peripheral neuropathy with implications for plantar foot ulceration. This meta-analysis aimed to compare the plantar pressures of diabetes patients that had peripheral neuropathy and those with neuropathy with active or previous foot ulcers. Published articles were identified from Medline via OVID, CINAHL, SCOPUS, INFORMIT, Cochrane Central EMBASE via OVID and Web of Science via ISI Web of Knowledge bibliographic databases. Observational studies reporting barefoot dynamic plantar pressure in adults with diabetic peripheral neuropathy, where at least one group had a history of plantar foot ulcers were included. Interventional studies, shod plantar pressure studies and studies not published in English were excluded. Overall mean peak plantar pressure (MPP) and pressure time integral (PTI) were primary outcomes. The six secondary outcomes were MPP and PTI at the rear foot, mid foot and fore foot. The protocol of the meta-analysis was published with PROPSERO, (registration number CRD42013004310). Eight observational studies were included. Overall MPP and PTI were greater in diabetic peripheral neuropathy patients with foot ulceration compared to those without ulceration (standardised mean difference 0.551, 95% CI 0.290-0.811, pdiabetic peripheral neuropathy with a history of foot ulceration compared to those with diabetic neuropathy without a history of ulceration. More homogenous data is needed to confirm these findings.

Volcanostratigraphic Approach for Evaluation of Geothermal Potential in Galunggung Volcano

Science.gov (United States)

Ramadhan, Q. S.; Sianipar, J. Y.; Pratopo, A. K.

2016-09-01

he geothermal systems in Indonesia are primarily associated with volcanoes. There are over 100 volcanoes located on Sumatra, Java, and in the eastern part of Indonesia. Volcanostratigraphy is one of the methods that is used in the early stage for the exploration of volcanic geothermal system to identify the characteristics of the volcano. The stratigraphy of Galunggung Volcano is identified based on 1:100.000 scale topographic map of Tasikmalaya sheet, 1:50.000 scale topographic map and also geological map. The schematic flowchart for evaluation of geothermal exploration is used to interpret and evaluate geothermal potential in volcanic regions. Volcanostratigraphy study has been done on Galunggung Volcano and Talaga Bodas Volcano, West Java, Indonesia. Based on the interpretation of topographic map and analysis of the dimension, rock composition, age and stress regime, we conclude that both Galunggung Volcano and Talaga Bodas Volcano have a geothermal resource potential that deserve further investigation.

[Diagnosis of gastric ulcer in the elderly].

Science.gov (United States)

Ashida, Kiyoshi; Fukuchi, Takumi; Yamashita, Hiroshi

2010-11-01

It is well known that gastric ulcers are most often found at anglus and upper corpus in the elderly. The number of gastric ulcer found at upper corpus hold half of all cases in the elderly patients with bleeding ulcer. Sixty percent of the elderly patients with bleeding ulcer took NSAIDs including low-dose aspirin in authors' hospital. Now it is easy to treat and cure bleeding ulcers due to development of endoscopic hemostasis and antiulcer drugs such as proton pump inhibitor(PPI). However, the elderly patients sometimes result in fatal outcome on bleeding from gastric ulcer. Therefore, it is important to prevent ulcer complications by PPI for the high-risk group such as elderly patients taking NSAIDs.

Venous leg ulcers

Science.gov (United States)

2008-01-01

Introduction Leg ulcers usually occur secondary to venous reflux or obstruction, but 20% of people with leg ulcers have arterial disease, with or without venous disorders. Between 1.5 and 3.0/1000 people have active leg ulcers. Prevalence increases with age to about 20/1000 in people aged over 80 years. Methods and outcomes We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of standard treatments, adjuvant treatments, and organisational interventions for venous leg ulcers? What are the effects of interventions to prevent recurrence of venous leg ulcers? We searched: Medline, Embase, The Cochrane Library, and other important databases up to September 2007 (BMJ Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results We found 80 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions In this systematic review we present information relating to the effectiveness and safety of the following interventions: compression bandages and stockings, cultured allogenic (single or bilayer) skin replacement, debriding agents, dressings (cellulose, collagen, film, foam, hyaluronic acid-derived, semi-occlusive alginate), hydrocolloid (occlusive) dressings in the presence of compression, intermittent pneumatic compression, intravenous prostaglandin E1, larval therapy, laser treatment (low-level), leg ulcer clinics, multilayer elastic system, multilayer elastomeric (or non-elastomeric) high-compression regimens or bandages, oral treatments (aspirin, flavonoids, pentoxifylline, rutosides, stanozolol, sulodexide, thromboxane alpha2 antagonists, zinc), peri-ulcer

Engaging patients in pressure ulcer prevention.

Science.gov (United States)

Hudgell, Lynne; Dalphinis, Julie; Blunt, Chris; Zonouzi, Maryam; Procter, Susan

2015-05-06

As patients increasingly care for themselves at home, they require accessible information to enable informed self-care. This article describes the development of an educational electronic application (app) designed for use by patients at risk of pressure ulcers, and their carers. The app can be downloaded to Windows, Android or Apple smartphones or tablets. The app is based on the current pressure ulcer prevention and management guidelines from the National Pressure Ulcer Advisory Panel and the National Institute for Health and Care Excellence, and is designed to educate patients and carers about how to prevent a pressure ulcer, how to recognise a pressure ulcer, and what to do if they suspect they are developing a pressure ulcer. We hope the app will be used to help with educational conversations among patients, carers and healthcare professionals.

Pain in interstitial cystitis/bladder pain syndrome: do characteristics differ in ulcerative and non-ulcerative subtypes?

Science.gov (United States)

Killinger, Kim A; Boura, Judith A; Peters, Kenneth M

2013-08-01

Key differences between interstitial cystitis/bladder pain syndrome (IC/BPS) subtypes (with and without Hunner's ulcer) have been noted. We hypothesized that pain characteristics in women grouped by IC/BPS subtype would differ. A survey was mailed to 749 women to assess IC/BPS pain and other characteristics. Cystoscopy/hydrodistention reports were reviewed for presence/absence of Hunner's ulcer. The McGill Pain Questionnaire Short Form© (MPQ-SF), Brief Pain Inventory (BPI), and Interstitial Cystitis Symptom and Problem Indices (ICSI-PI) assessed symptoms. Data were analyzed with Pearson's chi-square, Fisher's exact, t tests, and Wilcoxon rank tests. Of the 214 women that returned a survey (36 ulcerative and 178 non-ulcerative IC/BPS), similar proportions in each group reported that certain foods, exercise, and/or stress triggered symptoms. Fewer ulcerative patients reported pain with vaginal penetration than non-ulcerative (5/33, 15.2 % vs 76/160, 47.5 %; p = 0.0006). On the BPI, the ulcerative and non-ulcerative groups reported similar numbers of painful areas (mean 4.1 ± 6.1 and 4.1 ± 3.8; p = 0.33), and lower abdominal/pelvic pain was reported most (13/35, 37 % vs 79/172, 46 %; p = 0.34) followed by lower back pain (12/35, 34 % vs 69/172, 40 %; p = 0.52). Even though ICSI-PI, MPQ-SF, and BPI scores/responses did not differ, on the MPQ-SF the three words most frequently used by ulcerative patients to describe their pain were sharp, stabbing, and hot burning, and in non-ulcerative were aching, cramping, and tender. These measures did not reveal any significant differences in pain between subtypes. More research is needed in larger samples to determine whether differences exist.

[Peptic ulcer disease and stress].

Science.gov (United States)

Herszényi, László; Juhász, Márk; Mihály, Emese; Tulassay, Zsolt

2015-08-30

The discovery that Helicobacter pylori infection is the major cause of peptic ulcer disease revolutionised our views on the etiology and treatment of the disease. This discovery has tempted many experts to conclude that psychological factors and, specifically, stress are unimportant. However, Helicobacter pylori infection alone does not explain fully the incidence and prevalence of peptic ulcer disease. It has been demonstrated that stress can cause peptic ulcer disease even in the absence of Helicobacter pylori infection, supporting a multicausal model of peptic ulcer etiology. Psychological stress among other risk factors can function as a cofactor with Helicobacter pylori infection.

Magma supply, storage, and transport at shield-stage Hawaiian volcanoes: Chapter 5 in Characteristics of Hawaiian volcanoes

Science.gov (United States)

Poland, Michael P.; Miklius, Asta; Montgomery-Brown, Emily K.; Poland, Michael P.; Takahashi, T. Jane; Landowski, Claire M.

2014-01-01

The characteristics of magma supply, storage, and transport are among the most critical parameters governing volcanic activity, yet they remain largely unconstrained because all three processes are hidden beneath the surface. Hawaiian volcanoes, particularly Kīlauea and Mauna Loa, offer excellent prospects for studying subsurface magmatic processes, owing to their accessibility and frequent eruptive and intrusive activity. In addition, the Hawaiian Volcano Observatory, founded in 1912, maintains long records of geological, geophysical, and geochemical data. As a result, Hawaiian volcanoes have served as both a model for basaltic volcanism in general and a starting point for many studies of volcanic processes.

Muons reveal the interior of volcanoes

CERN Multimedia

Francesco Poppi

2010-01-01

The MU-RAY project has the very challenging aim of providing a “muon X-ray” of the Vesuvius volcano (Italy) using a detector that records the muons hitting it after traversing the rock structures of the volcano. This technique was used for the first time in 1971 by the Nobel Prize-winner Louis Alvarez, who was searching for unknown burial chambers in the Chephren pyramid.   The location of the muon detector on the slopes of the Vesuvius volcano. Like X-ray scans of the human body, muon radiography allows researchers to obtain an image of the internal structures of the upper levels of volcanoes. Although such an image cannot help to predict ‘when’ an eruption might occur, it can, if combined with other observations, help to foresee ‘how’ it could develop and serves as a powerful tool for the study of geological structures. Muons come from the interaction of cosmic rays with the Earth's atmosphere. They are able to traverse layers of ro...

Interdisciplinary studies of eruption at Chaiten Volcano, Chile

Science.gov (United States)

John S. Pallister; Jon J. Major; Thomas C. Pierson; Richard P. Hoblitt; Jacob B. Lowenstern; John C. Eichelberger; Lara. Luis; Hugo Moreno; Jorge Munoz; Jonathan M. Castro; Andres Iroume; Andrea Andreoli; Julia Jones; Fred Swanson; Charlie Crisafulli

2010-01-01

There was keen interest within the volcanology community when the first large eruption of high-silica rhyolite since that of Alaska's Novarupta volcano in 1912 began on 1 May 2008 at Chaiten volcano, southern Chile, a 3-kilometer-diameter caldera volcano with a prehistoric record of rhyolite eruptions. Vigorous explosions occurred through 8 May 2008, after which...

The Massive Compound Cofre de Perote Shield Volcano: a Volcanological Oddity in the Eastern Mexican Volcanic Belt

Science.gov (United States)

Siebert, L.; Carrasco-Nunez, G.; Diaz-Castellon, R.; Rodriguez, J. L.

2007-12-01

Cofre de Perote volcano anchors the northern end of the easternmost of several volcanic chains orthogonal to the E-W trend of the Mexican Volcanic Belt (MVB). Its structure, geochemistry, and volcanic history diverge significantly from that of the large dominantly andesitic stratovolcanoes that have been the major focus of research efforts in the MVB. Andesitic-trachyandesitic to dacitic-trachydacitic effusive activity has predominated at Cofre de Perote, forming a massive low-angle compound shield volcano that dwarfs the more typical smaller shield volcanoes of the central and western MVB. The 4282-m-high volcano overlooking Xalapa, the capital city of the State of Veracruz, has a diameter of about 30 km and rises more than 3000 m above the coastal plain to the east. Repeated edifice collapse has left massive horseshoe-shaped scarps that truncate the eastern side of the edifice. Five major evolutionary stages characterize the growth of this compound volcano: 1) emplacement of a multiple-vent dome complex forming the basal structure of Cofre de Perote around 1.9-1.3 Ma; 2) construction of the basal part of the compound shield volcano from at least two main upper-edifice vents at about 400 ka; 3) effusion of the summit dome-like lavas through multiple vents at ca. 240 ka; 4) eruption of a large number of geochemically diverse, alkaline and calc-alkaline Pleistocene-to-Holocene monogenetic cones (likely related to regional volcanism) through the flanks of the Cofre de Perote edifice; 5) late-stage, large-volume edifice collapse on at least two occasions (ca. 40 ka and ca. 10 ka), producing long-runout debris avalanches that traveled to the east. An undated tephra layer from Cofre de Perote overlies deposits likely of the youngest collapse. Cofre de Perote is one of several volcanoes in the roughly N-S-trending chain that has undergone major edifice collapse. As with Citlaltepetl (Pico de Orizaba) and Las Cumbres volcanoes, Cofre de Perote was constructed at the

The VCU Pressure Ulcer Summit-Developing Centers of Pressure Ulcer Prevention Excellence: A Framework for Sustainability.

Science.gov (United States)

Creehan, Sue; Cuddigan, Janet; Gonzales, Dana; Nix, Denise; Padula, William; Pittman, Joyce; Pontieri-Lewis, Vicky; Walden, Christine; Wells, Belinda; Wheeler, Robinetta

2016-01-01

Hospital-acquired pressure ulcer occurrences have declined over the past decade as reimbursement policies have changed, evidence-based practice guidelines have been implemented, and quality improvement initiatives have been launched. However, the 2006-2008 Institute for Healthcare Improvement goal of zero pressure ulcers remains difficult to achieve and even more challenging to sustain. Magnet hospitals tend to have lower hospital-acquired pressure ulcer rates than non-Magnet hospitals, yet many non-Magnet hospitals also have robust pressure ulcer prevention programs. Successful programs share commonalities in structure, processes, and outcomes. A national summit of 55 pressure ulcer experts was convened at the Virginia Commonwealth University Medical Center in March 2014. The group was divided into 3 focus groups; each was assigned a task to develop a framework describing components of a proposed Magnet-designated Center of Pressure Ulcer Prevention Excellence. Systematic literature reviews, analysis of exemplars, and nominal group process techniques were used to create the framework. This article presents a framework describing the proposed Magnet-designated Centers of Pressure Ulcer Prevention Excellence. Critical attributes of Centers of Excellence are identified and organized according to the 4 domains of the ANCC model for the Magnet Recognition Program: transformational leadership; structural empowerment; exemplary professional practice; and new knowledge innovation and improvements. The structures, processes, and outcome measures necessary to become a proposed Center of Pressure Ulcer Prevention Excellence are discussed.

Geology of kilauea volcano

Science.gov (United States)

Moore, R.B.; Trusdell, F.A.

1993-01-01

This paper summarizes studies of the structure, stratigraphy, petrology, drill holes, eruption frequency, and volcanic and seismic hazards of Kilauea volcano. All the volcano is discussed, but the focus is on its lower cast rift zone (LERZ) because active exploration for geothermal energy is concentrated in that area. Kilauea probably has several separate hydrothermal-convection systems that develop in response to the dynamic behavior of the volcano and the influx of abundant meteoric water. Important features of some of these hydrothermal-convection systems are known through studies of surface geology and drill holes. Observations of eruptions during the past two centuries, detailed geologic mapping, radiocarbon dating, and paleomagnetic secular-variation studies indicate that Kilauea has erupted frequently from its summit and two radial rift zones during Quaternary time. Petrologic studies have established that Kilauea erupts only tholeiitic basalt. Extensive ash deposits at Kilauea's summit and on its LERZ record locally violent, but temporary, disruptions of local hydrothermal-convection systems during the interaction of water or steam with magma. Recent drill holes on the LERZ provide data on the temperatures of the hydrothermal-convection systems, intensity of dike intrusion, porosity and permeability, and an increasing amount of hydrothermal alteration with depth. The prehistoric and historic record of volcanic and seismic activity indicates that magma will continue to be supplied to deep and shallow reservoirs beneath Kilauea's summit and rift zones and that the volcano will be affected by eruptions and earthquakes for many thousands of years. ?? 1993.

High cost of stage IV pressure ulcers.

Science.gov (United States)

Brem, Harold; Maggi, Jason; Nierman, David; Rolnitzky, Linda; Bell, David; Rennert, Robert; Golinko, Michael; Yan, Alan; Lyder, Courtney; Vladeck, Bruce

2010-10-01

The aim of this study was to calculate and analyze the cost of treatment for stage IV pressure ulcers. A retrospective chart analysis of patients with stage IV pressure ulcers was conducted. Hospital records and treatment outcomes of these patients were followed up for a maximum of 29 months and analyzed. Costs directly related to the treatment of pressure ulcers and their associated complications were calculated. Nineteen patients with stage IV pressure ulcers (11 hospital-acquired and 8 community-acquired) were identified and their charts were reviewed. The average hospital treatment cost associated with stage IV pressure ulcers and related complications was $129,248 for hospital-acquired ulcers during 1 admission, and $124,327 for community-acquired ulcers over an average of 4 admissions. The costs incurred from stage IV pressure ulcers are much greater than previously estimated. Halting the progression of early stage pressure ulcers has the potential to eradicate enormous pain and suffering, save thousands of lives, and reduce health care expenditures by millions of dollars. Copyright © 2010 Elsevier Inc. All rights reserved.

Silicic magma generation at Askja volcano, Iceland

Science.gov (United States)

Sigmarsson, O.

2009-04-01

Rate of magma differentiation is an important parameter for hazard assessment at active volcanoes. However, estimates of these rates depend on proper understanding of the underlying magmatic processes and magma generation. Differences in isotope ratios of O, Th and B between silicic and in contemporaneous basaltic magmas have been used to emphasize their origin by partial melting of hydrothermally altered metabasaltic crust in the rift-zones favoured by a strong geothermal gradient. An alternative model for the origin of silicic magmas in the Iceland has been proposed based on U-series results. Young mantle-derived mafic protolith is thought to be metasomatized and partially melted to form the silicic end-member. However, this model underestimates the compositional variations of the hydrothermally-altered basaltic crust. New data on U-Th disequilibria and O-isotopes in basalts and dacites from Askja volcano reveal a strong correlation between (230Th/232Th) and delta 18O. The 1875 AD dacite has the lowest Th- and O isotope ratios (0.94 and -0.24 per mille, respectively) whereas tephra of evolved basaltic composition, erupted 2 months earlier, has significantly higher values (1.03 and 2.8 per mille, respectively). Highest values are observed in the most recent basalts (erupted in 1920 and 1961) inside the Askja caldera complex and out on the associated fissure swarm (Sveinagja basalt). This correlation also holds for older magma such as an early Holocene dacites, which eruption may have been provoked by rapid glacier thinning. Silicic magmas at Askja volcano thus bear geochemical signatures that are best explained by partial melting of extensively hydrothermally altered crust and that the silicic magma source has remained constant during the Holocene at least. Once these silicic magmas are formed they appear to erupt rapidly rather than mixing and mingling with the incoming basalt heat-source that explains lack of icelandites and the bi-modal volcanism at Askja

The effects of antidepressants on gastric ulcer

Directory of Open Access Journals (Sweden)

Mehmet Latif Güneş

2013-12-01

Full Text Available In their daily practice, psychiatrists often experience gastriccomplaints in patients beside psychiatric disorders.Peptic ulcer is one of the diseases, which accompanyto psychiatric disorders including mainly depression. Itis shown that antidepressants can inflame the bleedingsincluding gastrointestinal (GI bleedings, while they havepositive effect on ulcer healing. In this review, studies,which conducted about the positive or negative effects ofantidepressant drugs on ulcer treatment were examined.Accordingly; it was found that opipramol, amitriptyline,imipramine that of tricyclic antidepressants was found tobe helpful in healing of the ulcer. It was stated that SelectiveSerotonin Reuptake Inhibitors generally inflamedulcers, exceptionally fluvoxamine and fluoxetine reducedulcer; moclobemide that of monoamine-oxidase inhibitorand tianeptine and mirtazapine that of atypical antidepressantshad positive effect in ulcer healing. To be carefulin choosing the appropriate antidepressant in psychiatricpatients with gastric ulcer is important in the prognosisof both ulcer and depression.Key words: peptic ulcer; depression; antidepressant drugs

Chemical compositions of lavas from Myoko volcano group

International Nuclear Information System (INIS)

Hasenaka, Toshiaki; Yoshida, Takeyoshi; Hayatsu, Kenji.

1995-01-01

In the volcanic rocks produced in island arc and continental margin arc, the phenomena of magma mixing is observed considerably generally. The research on these phenomena has been carried out also in Japan, and the periodically refilled magma chamber model has been proposed. In this report, the results of the photon activation analysis for the volcanic rock samples of Myoko volcano, for which the magma chamber model that the supply of basalt magma is periodically received was proposed, and of which the age of eruption and the stratigraphy are clearly known, are shown, and the above model is examined together with the published data of fluorescent X-ray analysis and others. The history of activities and the rate of magma extrusion of Myoko volcano group are described. The modal compositions of the volcanic rock samples of Myoko and Kurohime volcanos, for which photon activation analysis was carried out, are shown and discussed. The results of the analysis of the chemical composition of 39 volcanic rock samples from Myoko, Kurohime and Iizuna volcanos are shown. The primary magma in Myoko volcano group, the crystallization differentiation depth and moisture content of magma in Myoko and Kurohime volcanos, the presumption of Felsic and Mafic end-members in R type andesite in Myoko volcano group, and the change of magma composition with lapse of time are described. (K.I.)

Chemical compositions of lavas from Myoko volcano group

Energy Technology Data Exchange (ETDEWEB)

Hasenaka, Toshiaki; Yoshida, Takeyoshi [Tohoku Univ., Sendai (Japan). Faculty of Science; Hayatsu, Kenji

1995-08-01

In the volcanic rocks produced in island arc and continental margin arc, the phenomena of magma mixing is observed considerably generally. The research on these phenomena has been carried out also in Japan, and the periodically refilled magma chamber model has been proposed. In this report, the results of the photon activation analysis for the volcanic rock samples of Myoko volcano, for which the magma chamber model that the supply of basalt magma is periodically received was proposed, and of which the age of eruption and the stratigraphy are clearly known, are shown, and the above model is examined together with the published data of fluorescent X-ray analysis and others. The history of activities and the rate of magma extrusion of Myoko volcano group are described. The modal compositions of the volcanic rock samples of Myoko and Kurohime volcanos, for which photon activation analysis was carried out, are shown and discussed. The results of the analysis of the chemical composition of 39 volcanic rock samples from Myoko, Kurohime and Iizuna volcanos are shown. The primary magma in Myoko volcano group, the crystallization differentiation depth and moisture content of magma in Myoko and Kurohime volcanos, the presumption of Felsic and Mafic end-members in R type andesite in Myoko volcano group, and the change of magma composition with lapse of time are described. (K.I.)

The Steroids for Corneal Ulcers Trial

Science.gov (United States)

Srinivasan, Muthiah; Mascarenhas, Jeena; Rajaraman, Revathi; Ravindran, Meenakshi; Lalitha, Prajna; Glidden, David V.; Ray, Kathryn J.; Hong, Kevin C.; Oldenburg, Catherine E.; Lee, Salena M.; Zegans, Michael E.; McLeod, Stephen D.; Lietman, Thomas M.; Acharya, Nisha R.

2013-01-01

Objectives To provide comprehensive trial methods and baseline data for the Steroids for Corneal Ulcers Trial and to present epidemiological characteristics such as risk factors, causative organisms, and ulcer severity. Methods Baseline data from a 1:1 randomized, placebo-controlled, double-masked clinical trial comparing prednisolone phosphate, 1%, with placebo as adjunctive therapy for the treatment of bacterial corneal ulcers. Eligible patients had a culture-positive bacterial corneal ulcer and had been taking moxifloxacin for 48 hours. The primary outcome for the trial is best spectacle-corrected visual acuity at 3 months from enrollment. This report provides comprehensive baseline data, including best spectacle-corrected visual acuity, infiltrate size, microbio-logical results, and patient demographics, for patients enrolled in the trial. Results Of 500 patients enrolled, 97% were in India. Two hundred twenty patients (44%) were agricultural workers. Median baseline visual acuity was 0.84 logMAR (Snellen, 20/125) (interquartile range, 0.36-1.7; Snellen, 20/50 to counting fingers). Baseline visual acuity was not significantly different between the United States and India. Ulcers in India had larger infiltrate/scar sizes (P=.04) and deeper infiltrates (P=.04) and were more likely to be localized centrally (P=.002) than ulcers enrolled in the United States. Gram-positive bacteria were the most common organisms isolated from the ulcers (n=366, 72%). Conclusions The Steroids for Corneal Ulcers Trial will compare the use of a topical corticosteroid with placebo as adjunctive therapy for bacterial corneal ulcers. Patients enrolled in this trial had diverse ulcer severity and on average significantly reduced visual acuity at presentation. PMID:21987581

[Quantity research on epidermal growth factor in saliva and epidermal growth factor receptor in biopsy samples of recurrent aphthous ulcer patients].

Science.gov (United States)

Gu, Yang; Zhang, Gang; Lin, Mei

2008-02-01

To examine the change of epidermal growth factor (EGF) concentration in saliva of recurrent aphthous ulcer (RAU) patients during the ulcerous and interval period and epidermal growth factor receptor (EGFR) in ulcer biopsy samples. ECF data of the samples, which were 27 saliva samples from RAU gained not only in the ulcerous period but also in interval period and 33 ones from normal persons, were acquired through enzyme linked immunosorhent assay (ELISA) and EGF standard curve. ECFR-RNA date of RAU biopsies, which were 31 biopsy samples from RAU got during the ulcerous period and 35 ones from normal persons, were surveyed by QF-RT-PCR. All RAU samples were obtained under the same level, which were the whole patients were minor aphthous ulcers and their ulcers occurred not over the first four days. All patients and normal persons were selected seriously under the rule of physical situations without any other diseases and histories of using medicines. The EGF concentration of saliva in RAU group at ulcer occurrence was higher than that in the interval period and the normal control with a significant test (F = 3.24, P ulcer occurrence was higher than the normal control with a significant test (t = 3.15, P ulcer occasion of RAU patients could be related with the decreasing of EGF in saliva during interval period, and that the ulcer sell-cure of RAU patients would be contributed to

Volcano Trial Case on GEP: Systematically processing EO data

OpenAIRE

Baumann, Andreas Bruno Graziano

2017-01-01

Volcanoes can be found all over the world; on land and below water surface. Even nowadays not all volcanoes are known. About 600 erupted in geologically recent times and about 50-70 volcanoes are currently active. Volcanoes can cause earthquakes; throw out blasts and tephras; release (toxic) gases; lava can flow relatively slow down the slopes; mass movements like debris avalanches, and landslides can cause tsunamis; and fast and hot pyroclastic surge, flows, and lahars can travel fast down ...

The "Mud-volcanoes route" (Emilia Apennines, northern Italy)

Science.gov (United States)

Coratza, Paola; Castaldini, Doriano

2016-04-01

In the present paper the "Mud-volcanoes route" (MVR), an itinerary unfolds across the districts of Viano, Sassuolo, Fiorano Modenese and Maranello, in which part of the Emilia mud volcanoes fields are located, is presented. The Mud-volanoes route represents an emotional journey that connects places and excellences through the geological phenomenon of mud volcanoes, known with the local name "Salse". The Mud Volcanoes are created by the surfacing of salt water and mud mixed with gaseous and liquid hydrocarbons along faults and fractures of the ground. The name "Salsa"- from Latin salsus - results from the"salt" content of these muddy waters, ancient heritage of the sea that about a million years ago was occupying the current Po Plain. The "Salse" may take the shape of a cone or a level-pool according to the density of the mud. The Salse of Nirano, in the district of Fiorano Modenese, is one of the most important in Italy and among the most complex in Europe. Less extensive but equally charming and spectacular, are the "Salse" located in the districts of Maranello (locality Puianello), Sassuolo (locality Montegibbio) and Viano (locality Casola Querciola and Regnano). These fascinating lunar landscapes have always attracted the interest of researchers and tourist.The presence on the MVR territory of ancient settlements, Roman furnaces and mansions, fortification systems and castles, besides historic and rural buildings, proves the lasting bond between this land and its men. In these places, where the culture of good food has become a resource, we can find wine cellars, dairy farms and Balsamic vinegar factories that enable us to appreciate unique worldwide products. This land gave also birth to some personalities who created unique worldwide famous values, such as the myth of the Ferrrari, the ceramic industry and the mechatronics. The MVR is represented in a leaflet containing, short explanation, photos and a map in which are located areas with mud volcanoes, castles

Factors Affecting Wound Healing in Individuals With Pressure Ulcers: A Retrospective Study.

Science.gov (United States)

Karahan, Azize; AAbbasoğlu, Aysel; Işık, Sevcan Avcı; Çevik, Banu; Saltan, Çiğdem; Elbaş, Nalan Özhan; Yalılı, Ayşe

2018-02-01

Owing to the number and severity of concomitant factors, pressure ulcers remain a significant problem. A retrospective study of data from adult patients with a pressure ulcer was conducted to identify factors that may affect their healing. Data from patients who were hospitalized between January 1, 2011, and December 31, 2015, in a private Turkish university hospital who had a Stage 2, Stage 3, Stage 4, or unstageable pressure ulcer that was assessed using the Bates-Jensen Wound Assessment Tool (BWAT) were abstracted. The following variables were examined: demographic characteristics (gender, age, hospital unit, duration of hospitalization), health status and disease data (vital signs, mobility, nutrition, diagnosis, chronic diseases, medication), laboratory values (albumin, hemoglobin, blood glucose), and pressure ulcer characteristics (stage, location, healing status, duration) and pressure ulcer risk status as determined by patient Braden Scale score. Seventy-eight (78) patient records were identified. Patient mean age was 70.8 ± 13.47 years, and length of hospitalization was on average 32.52 ± 27.2 days. Most ulcers (62; 79.5%) were Stage 2 and located in the sacral area (59; 75.6%). Thirty-four (34) patients (43.6%) were discharged and 44 (56.4%) died. At the time of discharge or death, 65.4% of the ulcers had not healed. Patients whose wounds were healed were significantly more likely to have higher hemoglobin and mean arterial pressure, better mobility, received oral nutrition, and discharged from the hospital than patients whose ulcers did not heal. The results suggest that these variables, including Braden Scale and BWAT scores, might be considered when developing a treatment plan of care. Additional studies examining risk factors for nonhealing pressure ulcers, including studies with large samples to facilitate multivariate analyses, are needed.

Treatment of peptic ulcer

NARCIS (Netherlands)

Tytgat, G. N.

1998-01-01

The current therapy of choice for all Helicobacter pylori-associated ulcer disease is eradication therapy. Although adequate therapeutic regimens are currently available, often still ineffective therapies are tried. Cure of the infection essentially eliminates the ulcer diathesis. Cure of the

Pressure ulcers: effectiveness of risk-assessment tools. A randomised controlled trial (the ULCER trial).

Science.gov (United States)

Webster, Joan; Coleman, Kerrie; Mudge, Alison; Marquart, Louise; Gardner, Glenn; Stankiewicz, Monica; Kirby, Julie; Vellacott, Catherine; Horton-Breshears, Margaret; McClymont, Alice

2011-04-01

To evaluate the effectiveness of two pressure-ulcer screening tools against clinical judgement in preventing pressure ulcers. A single blind randomised controlled trial. A large metropolitan tertiary hospital. 1231 patients admitted to internal medicine or oncology wards. Patients were excluded if their hospital stay was expected to be 2 days or less. Participants allocated to either a Waterlow (n=410) or Ramstadius (n=411) screening tool group or to a clinical judgement group (n=410) where no formal risk screening instrument was used. Incidence of hospital acquired pressure ulcers ascertained by regular direct observation. Use of any devices for the prevention of pressure ulcers, documentation of a pressure plan and any dietetic or specialist skin integrity review were recorded. On admission, 71 (5.8%) patients had an existing pressure ulcer. The incidence of hospital-acquired pressure ulcers was similar between groups (clinical judgement 28/410 (6.8%); Waterlow 31/411 (7.5%); Ramstadius 22/410 (5.4%), p=0.44). Significant associations with pressure injury in regression modelling included requiring a dietetic referral, being admitted from a location other than home and age over 65 years. The authors found no evidence to show that two common pressure-ulcer risk-assessment tools are superior to clinical judgement to prevent pressure injury. Resources associated with use of these tools might be better spent on careful daily skin inspection and improving management targetted at specific risks. The trial was registered with the Australian and New Zealand Clinicat Trials Registry (ACTRN 12608000541303).

The cost of prevention and treatment of pressure ulcers: A systematic review.

Science.gov (United States)

Demarré, Liesbet; Van Lancker, Aurélie; Van Hecke, Ann; Verhaeghe, Sofie; Grypdonck, Maria; Lemey, Juul; Annemans, Lieven; Beeckman, Dimitri

2015-11-01

to patients at risk can importantly impact health care services' budgets, the costs to treat a severe pressure ulcer were found to be substantially higher. Methodological heterogeneity among studies identified the need to use available, and study design-specific methodological guidelines to conduct health economic studies, and the need for additional pressure ulcer specific recommendations. Copyright © 2015 Elsevier Ltd. All rights reserved.

Retrospective validation of a lava-flow hazard map for Mount Etna volcano

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Ciro Del Negro

2011-12-01

Full Text Available This report presents a retrospective methodology to validate a long-term hazard map related to lava-flow invasion at Mount Etna, the most active volcano in Europe. A lava-flow hazard map provides the probability that a specific point will be affected by potential destructive volcanic processes over the time period considered. We constructed this lava-flow hazard map for Mount Etna volcano through the identification of the emission regions with the highest probabilities of eruptive vents and through characterization of the event types for the numerical simulations and the computation of the eruptive probabilities. Numerical simulations of lava-flow paths were carried out using the MAGFLOW cellular automata model. To validate the methodology developed, a hazard map was built by considering only the eruptions that occurred at Mount Etna before 1981. On the basis of the probability of coverage by lava flows, the map was divided into ten classes, and two fitting scores were calculated to measure the overlap between the hazard classes and the actual shapes of the lava flows that occurred after 1981.

Iridium emissions from Hawaiian volcanoes

International Nuclear Information System (INIS)

Finnegan, D.L.; Zoller, W.H.; Miller, T.M.

1988-01-01

Particle and gas samples were collected at Mauna Loa volcano during and after its eruption in March and April, 1984 and at Kilauea volcano in 1983, 1984, and 1985 during various phases of its ongoing activity. In the last two Kilauea sampling missions, samples were collected during eruptive activity. The samples were collected using a filterpack system consisting of a Teflon particle filter followed by a series of 4 base-treated Whatman filters. The samples were analyzed by INAA for over 40 elements. As previously reported in the literature, Ir was first detected on particle filters at the Mauna Loa Observatory and later from non-erupting high temperature vents at Kilauea. Since that time Ir was found in samples collected at Kilauea and Mauna Loa during fountaining activity as well as after eruptive activity. Enrichment factors for Ir in the volcanic fumes range from 10,000 to 100,000 relative to BHVO. Charcoal impregnated filters following a particle filter were collected to see if a significant amount of the Ir was in the gas phase during sample collection. Iridium was found on charcoal filters collected close to the vent, no Ir was found on the charcoal filters. This indicates that all of the Ir is in particulate form very soon after its release. Ratios of Ir to F and Cl were calculated for the samples from Mauna Loa and Kilauea collected during fountaining activity. The implications for the KT Ir anomaly are still unclear though as Ir was not found at volcanoes other than those at Hawaii. Further investigations are needed at other volcanoes to ascertain if basaltic volcanoes other than hot spots have Ir enrichments in their fumes

Iridium emissions from Hawaiian volcanoes

Science.gov (United States)

Finnegan, D. L.; Zoller, W. H.; Miller, T. M.

1988-01-01

Particle and gas samples were collected at Mauna Loa volcano during and after its eruption in March and April, 1984 and at Kilauea volcano in 1983, 1984, and 1985 during various phases of its ongoing activity. In the last two Kilauea sampling missions, samples were collected during eruptive activity. The samples were collected using a filterpack system consisting of a Teflon particle filter followed by a series of 4 base-treated Whatman filters. The samples were analyzed by INAA for over 40 elements. As previously reported in the literature, Ir was first detected on particle filters at the Mauna Loa Observatory and later from non-erupting high temperature vents at Kilauea. Since that time Ir was found in samples collected at Kilauea and Mauna Loa during fountaining activity as well as after eruptive activity. Enrichment factors for Ir in the volcanic fumes range from 10,000 to 100,000 relative to BHVO. Charcoal impregnated filters following a particle filter were collected to see if a significant amount of the Ir was in the gas phase during sample collection. Iridium was found on charcoal filters collected close to the vent, no Ir was found on the charcoal filters. This indicates that all of the Ir is in particulate form very soon after its release. Ratios of Ir to F and Cl were calculated for the samples from Mauna Loa and Kilauea collected during fountaining activity. The implications for the KT Ir anomaly are still unclear though as Ir was not found at volcanoes other than those at Hawaii. Further investigations are needed at other volcanoes to ascertain if basaltic volcanoes other than hot spots have Ir enrichments in their fumes.

[Efficacy of compression knee-high socks ULCER X in treatment of venous-genesis trophic ulcers].

Science.gov (United States)

Bogdanets, L I; Bogachev, V Iu; Lobanov, V N; Smirnova, E S

2013-01-01

The study was aimed at comparatively assessing the efficacy of treatment for venous trophic ulcers at stages II-III of the wound process using special compression knee-length socks of the ULCER X kit (Sigvaris AG, St. Gallen, Switzerland) and long-stretch bandages Lauma. Compression therapy was included into the programme of outpatient treatment of forty 31-to-74-year-old patients presenting with trophic ulcers (stage II-III of the wound process) with an average area of 5,36±1,1 cm2. The Study Group consisting of 20 patients used compression knitted fabrics in the form of knee-length socks ULCER X and the comparison group (n=20) used long-stretch bandages Lauma. The obtained findings (6 months) demonstrated that using compression therapy exerted a positive effect on the process of healing of venous trophic ulcers, also proving advantages of compression therapy with the knee-length socks ULCER X that create an adequate level of pressure on the crus and maintain it in long-term daily use, reliably accelerating the healing of venous trophic ulcers as compared with elastic long-stretch bandages. The use of long-stretch elastic bandages in treatment of venous trophic ulcers turned out to be not only ineffective but fraught with a possibility of the development of various complications. During 6 months of follow up the patients using the special knee-length socks ULCER X were found to have 80 % of ulcers healed (16 patients), mainly within the first 2 months, whereas using elastic bandages resulted in only 30 % of healing (6 patients) by the end of the study. Along with it, we documented a considerable decrease in the malleolar circumference in the study group patients (from 30,05±0,78 to 28,35±0,86 cm) and in the control group from 31,2±30,35 to 30,25±0,75 cm), accompanied and followed by more than a two-fold increase in quality of life of the patients along all the parameters in the study group and a 1.4-fold increase in the control group patients.

Evaluation of Anti-ulcer Activity of Echinops Persicus on Experimental Gastric Ulcer Models in Rats

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Ahmad Farajzadeh-Sheikh

2010-12-01

Full Text Available Extract of Echinops persicus is traditionally used for a long time in Iran for treatment of cough and constipation. This extract is produced by activity of bug (Situphilus spp. on the plant. We documented its anti-tussive effect in rats in our previous study.The aim of this study was to assess the anti-ulcer effect of Echinops persicus in an animal model. In this study we evaluated anti-ulcer effect of Echinops persicus by Shay's method in rats. In 3 groups of rats, pylorus was ligatured under anesthesia. The rats were euthanized after 19 hours later and number and level of ulcer in stomach was measured. In group 2 the extract was orally administered 45 minutes before pyloric ligature, and in group 3, it was administered intraperitoneally 20 minutes before pyloric ligature. The number of ulcers in stomach was significantly low in group 2 (P = 0.01 and 3 (P = 0.037 in comparison with group 1. The level of ulcer was significantly decreased in group 2 (P = 0.047 with comparison to group 1. We conclude that, Echinops extract can exhibit potentially cytoprotective and anti-ulcer activity.

Geochemical and Geophysical Signatures of Poas Volcano, Costa Rica

Science.gov (United States)

Martinez, M.; van Bergen, M.; Fernandez, E.; Takano, B.; Barboza, V.; Saenz, W.

2007-05-01

Among many research fields in volcanology, prediction of eruptions is the most important from the hazard- mitigation point of view. Most geophysicists have sought for the best physical parameters for this objective: various kinds of wave signals and geodesic data are two of such parameters. Being able to be remotely monitored gives them advantage over many other practical methods for volcano monitoring. On the other hand, increasing volcanic activity is always accompanied by mass transfer. The most swiftly-moving materials are volcanic gases which are the target geochemists have intensively studied although monitoring gases is rather tedious and limited for active volcanoes hosting crater lakes. A Japanese group lead by Bokuichiro Takano has recently developed an indirect method for monitoring gas injection into volcanic crater lakes. Polythionates are formed when SO2 and H2S are injected into the lake from subaqueous fumaroles. Such polythionates consist of chains of 4 to 6 sulphur atoms, the terminal ones of which are bonded with three oxygen atoms. The general formula for these anions is SxO62- (x= 4 to 6). Important to note is that SO2 input into the lake also depends upon the plumbing system of the volcanoes: conduits, cracks and hydrothermal reservoirs beneath the lake that usually differ from volcano to volcano. Despite such site-specific characters some general statements can be made on the behaviour of these chemical species. For example, at low volcanic activity S6O62- predominates while S4O62- and S5O62- become predominant with increasing SO2 that increases with volcanic activity. At higher SO2 input and high temperature polythionates disappear in the lake through interaction with aqueous SO2 (sulfitolysis). Thus, the ratios of the three polythionates or their absence serve as an indicator for various stages of volcanic activity. Monitoring polythionates is an independent method that can be compared with results from geophysical methods. However, it

Modeling volcano growth on the Island of Hawaii: deep-water perspectives

Science.gov (United States)

Lipman, Peter W.; Calvert, Andrew T.

2013-01-01

Recent ocean-bottom geophysical surveys, dredging, and dives, which complement surface data and scientific drilling at the Island of Hawaii, document that evolutionary stages during volcano growth are more diverse than previously described. Based on combining available composition, isotopic age, and geologically constrained volume data for each of the component volcanoes, this overview provides the first integrated models for overall growth of any Hawaiian island. In contrast to prior morphologic models for volcano evolution (preshield, shield, postshield), growth increasingly can be tracked by age and volume (magma supply), defining waxing alkalic, sustained tholeiitic, and waning alkalic stages. Data and estimates for individual volcanoes are used to model changing magma supply during successive compositional stages, to place limits on volcano life spans, and to interpret composite assembly of the island. Volcano volumes vary by an order of magnitude; peak magma supply also varies sizably among edifices but is challenging to quantify because of uncertainty about volcano life spans. Three alternative models are compared: (1) near-constant volcano propagation, (2) near-equal volcano durations, (3) high peak-tholeiite magma supply. These models define inconsistencies with prior geodynamic models, indicate that composite growth at Hawaii peaked ca. 800–400 ka, and demonstrate a lower current rate. Recent age determinations for Kilauea and Kohala define a volcano propagation rate of 8.6 cm/yr that yields plausible inception ages for other volcanoes of the Kea trend. In contrast, a similar propagation rate for the less-constrained Loa trend would require inception of Loihi Seamount in the future and ages that become implausibly large for the older volcanoes. An alternative rate of 10.6 cm/yr for Loa-trend volcanoes is reasonably consistent with ages and volcano spacing, but younger Loa volcanoes are offset from the Kea trend in age-distance plots. Variable magma flux

Bidirectional crosstalk between stress-induced gastric ulcer and depression under chronic stress.

Directory of Open Access Journals (Sweden)

Shuang Zhang

Full Text Available Stress contributes to a variety of diseases and disorders such as depression and peptic ulcer. The present study aimed to investigate the correlation between stress ulcer and depression in pathogenesis and treatment by using chronic stress depression (CSD, chronic psychological stress ulcer (CPSU and water immersion restrain stress models in rats. Our data showed that the ulcer index of the animals after CSD exposure was significantly higher than that of controls. Depression-like behaviors were observed in rat after CPSU exposure. Fluoxetine hydrochloride significantly reduced the ulcer index of rats exposed to CPSU stress, while ranitidine inhibited depression-like behavior of the animals in CSD group. The ulcer index of rats administered with mifepristone after CPSU stress was markedly reduced compared to CPSU group, although there was no significant difference in the depression-like behavior between mifepristone-treated CSD group and naive controls. We also found that the rats exposed to CPSU or CSD stress displayed a lower level of corticosterone than naive controls, however, the acute stress (AS group showed an opposite result. Additionally, in order to study the relevance of H(2 receptors and depression, we treated the CSD group with cimetidine and famotidine respectively. The data showed that cimetidine inhibited depression-like behavior in CSD rats, and famotidine had no impact on depression. Overall our data suggested that the hypothalamic-pituitary-adrenal (HPA axis dysfunction may be the key role in triggering depression and stress ulcer. Acid-suppressing drugs and antidepressants could be used for treatment of depression and stress ulcer respectively. The occurrence of depression might be inhibited by blocking the central H(2 receptors.

Anti-inflammatory Activities and Gastric Ulcer-inducing Properties of Tetraacetylquercetin and Tetrapivaloylquercetin

Directory of Open Access Journals (Sweden)

Rina Herowati

2016-12-01

Full Text Available Quercetin (3,3’4’,5,7-pentahydroxyflavone has been reported to show anti-inflammatory activity. However, its low oral bioavailability limits the application of quercetin in therapy. Ester derivatives of quercetin have been reported to have higher bioavailability than quercetin. This research aimed to study the anti-inflammatory activities and gastric ulcer-inducing properties of tetraacetylquercetinas well as tetrapivaloylquercetin. Synthesis of tetra-acyl derivatives of quercetin was conducted using acetic anhydride or pivaloyl chloride in the presence of pyridine and the structure was confirmed by 1H-NMR and 13C-NMR spectroscopy as well as elemental analysis. At a dose of 20 mg/kg bw, oral administration of quercetin only showed 20% inhibition activity on carragenan induced rat paw edema, while tetraacetyl and tetrapivaloyl derivatives at equimolar dose showed 11-33% and 5-15% inhibition activity respectively. Contrary to the gastric ulcer healing-promoting action of quercetin, tetraacetylquercetin caused mild gastric ulcers. However, no gastric ulcer was observed after administration of tetrapivaloylquercetin. It was concluded that acylation enhances the anti-inflammatory activity of quercetin but causes mild gastric ulcers in the case of tetraacetylation.

Volcanoes muon imaging using Cherenkov telescopes

Energy Technology Data Exchange (ETDEWEB)

Catalano, O. [INAF, Istituto di Astrofisica Spaziale e Fisica cosmica di Palermo, via U. La Malfa 153, I-90146 Palermo (Italy); Del Santo, M., E-mail: melania@ifc.inaf.it [INAF, Istituto di Astrofisica Spaziale e Fisica cosmica di Palermo, via U. La Malfa 153, I-90146 Palermo (Italy); Mineo, T.; Cusumano, G.; Maccarone, M.C. [INAF, Istituto di Astrofisica Spaziale e Fisica cosmica di Palermo, via U. La Malfa 153, I-90146 Palermo (Italy); Pareschi, G. [INAF Osservatorio Astronomico di Brera, Via E. Bianchi 46, I-23807, Merate (Italy)

2016-01-21

A detailed understanding of a volcano inner structure is one of the key-points for the volcanic hazards evaluation. To this aim, in the last decade, geophysical radiography techniques using cosmic muon particles have been proposed. By measuring the differential attenuation of the muon flux as a function of the amount of rock crossed along different directions, it is possible to determine the density distribution of the interior of a volcano. Up to now, a number of experiments have been based on the detection of the muon tracks crossing hodoscopes, made up of scintillators or nuclear emulsion planes. Using telescopes based on the atmospheric Cherenkov imaging technique, we propose a new approach to study the interior of volcanoes detecting of the Cherenkov light produced by relativistic cosmic-ray muons that survive after crossing the volcano. The Cherenkov light produced along the muon path is imaged as a typical annular pattern containing all the essential information to reconstruct particle direction and energy. Our new approach offers the advantage of a negligible background and an improved spatial resolution. To test the feasibility of our new method, we have carried out simulations with a toy-model based on the geometrical parameters of ASTRI SST-2M, i.e. the imaging atmospheric Cherenkov telescope currently under installation onto the Etna volcano. Comparing the results of our simulations with previous experiments based on particle detectors, we gain at least a factor of 10 in sensitivity. The result of this study shows that we resolve an empty cylinder with a radius of about 100 m located inside a volcano in less than 4 days, which implies a limit on the magma velocity of 5 m/h.

Volcanoes muon imaging using Cherenkov telescopes

International Nuclear Information System (INIS)

Catalano, O.; Del Santo, M.; Mineo, T.; Cusumano, G.; Maccarone, M.C.; Pareschi, G.

2016-01-01

A detailed understanding of a volcano inner structure is one of the key-points for the volcanic hazards evaluation. To this aim, in the last decade, geophysical radiography techniques using cosmic muon particles have been proposed. By measuring the differential attenuation of the muon flux as a function of the amount of rock crossed along different directions, it is possible to determine the density distribution of the interior of a volcano. Up to now, a number of experiments have been based on the detection of the muon tracks crossing hodoscopes, made up of scintillators or nuclear emulsion planes. Using telescopes based on the atmospheric Cherenkov imaging technique, we propose a new approach to study the interior of volcanoes detecting of the Cherenkov light produced by relativistic cosmic-ray muons that survive after crossing the volcano. The Cherenkov light produced along the muon path is imaged as a typical annular pattern containing all the essential information to reconstruct particle direction and energy. Our new approach offers the advantage of a negligible background and an improved spatial resolution. To test the feasibility of our new method, we have carried out simulations with a toy-model based on the geometrical parameters of ASTRI SST-2M, i.e. the imaging atmospheric Cherenkov telescope currently under installation onto the Etna volcano. Comparing the results of our simulations with previous experiments based on particle detectors, we gain at least a factor of 10 in sensitivity. The result of this study shows that we resolve an empty cylinder with a radius of about 100 m located inside a volcano in less than 4 days, which implies a limit on the magma velocity of 5 m/h.

A Randomized Controlled Trial Comparing Telemedical and Standard Outpatient Monitoring of Diabetic Foot Ulcers

DEFF Research Database (Denmark)

Rasmussen, Benjamin S B; Froekjaer, Johnny; Bjerregaard, Mads R

2015-01-01

OBJECTIVE: The role of telemedical monitoring in diabetic foot ulcer care is still uncertain. Our aim was to compare telemedical and standard outpatient monitoring in the care of patients with diabetic foot ulcers in a randomized controlled trial. RESEARCH DESIGN AND METHODS: Of the 736 screened...... individuals with diabetic foot ulcers, 401 met the eligibility criteria and were randomized between October 2010 and November 2014. The per-protocol telemedical monitoring consisted of two consultations in the patient's own home and one consultation at the outpatient clinic. Standard practice consisted...... monitoring, a higher mortality throws into question the role of telemedicine in monitoring diabetic foot ulcers. Further studies are needed to investigate effects of telemedicine on mortality and other clinical outcomes and to identify patient subgroups that may have a poorer outcome through telemedical...

The stress ulcer syndrome

NARCIS (Netherlands)

H.A. van Essen

1986-01-01

textabstractThe stress ulcer syndrome is described in this thesis. This syndrome is seen in patients admitted to intensive care departments or being treated in field hospitals, in disaster areas, or battle fields. Acute mucosal lesions associated with burns (Curling's ulcers) and central nervous

Review : Pressure Ulcer and Its treatment

OpenAIRE

Bijan Khorasani; Ali Ghafouri

2004-01-01

Pressure ulcer is a signifcant problem in elderly and critically ill patients, causing pain, decreasing quality of life and leading to prolonged hospital stay. Treatment of pressure ulcer to improve health status is a cost-effective approach. So, preventing the ulcers will be economical. Pressure ulcer is considered as a damage or necrosis of skin and its layers, which happens when there is a considerable pressure over the tissues. If the capillary arterie's pressure reaches 70 mmHg (2 ti...

Geology of Kilauea volcano

Energy Technology Data Exchange (ETDEWEB)

Moore, R.B. (Geological Survey, Denver, CO (United States). Federal Center); Trusdell, F.A. (Geological Survey, Hawaii National Park, HI (United States). Hawaiian Volcano Observatory)

1993-08-01

This paper summarizes studies of the structure, stratigraphy, petrology, drill holes, eruption frequency, and volcanic and seismic hazards of Kilauea volcano. All the volcano is discussed, but the focus is on its lower east rift zone (LERZ) because active exploration for geothermal energy is concentrated in that area. Kilauea probably has several separate hydrothermal-convection systems that develop in response to the dynamic behavior of the volcano and the influx of abundant meteoric water. Important features of some of these hydrothermal-convection systems are known through studies of surface geology and drill holes. Observations of eruptions during the past two centuries, detailed geologic mapping, radiocarbon dating, and paleomagnetic secular-variation studies indicate that Kilauea has erupted frequently from its summit and two radial rift zones during Quaternary time. Petrologic studies have established that Kilauea erupts only tholeiitic basalt. Extensive ash deposits at Kilauea's summit and on its LERZ record locally violent, but temporary, disruptions of local hydrothermal-convection systems during the interaction of water or steam with magma. Recent drill holes on the LERZ provide data on the temperatures of the hydrothermal-convection systems, intensity of dike intrusion, porosity and permeability, and an increasing amount of hydrothermal alteration with depth. The prehistoric and historic record of volcanic and seismic activity indicates that magma will continue to be supplied to deep and shallow reservoirs beneath Kilauea's summit and rift zones and that the volcano will be affected by eruptions and earthquakes for many thousands of years. 71 refs., 2 figs.

Modified pectic polysaccharide from turmeric (Curcuma longa): A potent dietary component against gastric ulcer.

Science.gov (United States)

Harsha, Mysore R; Chandra Prakash, Serkad V; Dharmesh, Shylaja M

2016-03-15

Native, intact (TrPP) and modified, low-molecular-weight (MTrPP) forms of pectic polysaccharides isolated from turmeric were evaluated for ulcer-preventive potentials in in vitro and in vivo models. Data indicated that MTrPP possessed significantly better ulcer-preventive property than TrPP; inhibiting ulcer scores up to 85%. Results were substantiated by effective muco-protection, H(+),K(+)-ATPase down-regulation, inhibition of H. pylori growth/adherence, higher antioxidant/cytoprotective mechanisms. Structural data indicated TrPP and MTrPP differ in their molecular weights and structural characteristics with different sugar compositions and side chain ratios. MTrPP was rich in galacturonic acid (687mg/g; TrPP-544mg/g) and galactose (52.9%; TrPP-21.7%). Results were substantiated by NMR/FTIR data indicating the presence of homogalacturonan and rhamnogalacturonam-I containing galactans. By virtue of binding to inflammatory marker (galectin-3), galactans may reduce inflammation induced ulcerations. The low molecular weight of MTrPP (155kDa; TrPP-13kDa) may increase its bioavailability than TrPP, thus MTrPP may possess higher antiulcer potential. Copyright © 2015 Elsevier Ltd. All rights reserved.

[Having trouble with pressure ulcers care?].

Science.gov (United States)

Mizuno, Masako; Noda, Yasuhiro; Nohara, Yoko; Fujii, Keiko; Sato, Noriko; Renda, Akiyoshi; Yuasa, Takashi; Muramatsu, Shuichi; Furuta, Katsunori

2004-12-01

Since 1997, we, the community pharmacists, have established this society, Aichi Prefecture Society for the Study of Pressure Ulcers Care, in order to furnish drug information about pressure ulcers care. Moist atmosphere is required for the healing of pressure ulcers. The moist environment that could be regulated depends on the physicochemical property of ointment bases. Therefore, ointment should reasonably be chosen to adjust the moisture. Since 2000, we have been committed to providing pharmacists, who work on home care, with a booklet to instruct how to choose ointments for pressure ulcers treatment. In 2002, when the Aichi pharmaceutical association held a training conference held at various hospitals using the booklet as a teaching material, hospital pharmacists cooperated by making a field study trip to observe pressure ulcers treatments. Nowadays researchers at pharmaceutical colleges have also cooperated in studying the efficacy and economical effect of the method of blending different ointments to improve the healing process of pressure ulcers.

Incidence and risk factors for surgically acquired pressure ulcers: a prospective cohort study investigators.

Science.gov (United States)

Webster, Joan; Lister, Carolyn; Corry, Jean; Holland, Michelle; Coleman, Kerrie; Marquart, Louise

2015-01-01

To assess the incidence of hospital-acquired, surgery-related pressure injury (ulcers) and identify risk factors for these injuries. We used a prospective cohort study to investigate the research question. The study was conducted at a major metropolitan hospital in Brisbane, Australia. Five hundred thirty-four adult patients booked for any surgical procedure expected to last more than 30 minutes were eligible for inclusion. Patients who provided informed consent for study participation were assessed for pressure ulcers, using the European Pressure Ulcer Advisory Panel and National Pressure Ulcer Advisory Panel Guidelines, before entering the operating room and again in the post-anesthetic care unit (PACU). Research nurses and all PACU nurses were trained in skin assessment and in pressure ulcer staging. Patients were not assessed again after their discharge from the PACU. Seven patients (1.3%) had existing pressure injuries (ulcers) and a further 6 (1.3%) developed a surgery-related pressure ulcer. Risk factors associated with surgery-related pressure injuries were similar to non-surgically related risks and included older age, skin condition, and being admitted from a location other than one's own home. Length of surgery was not associated with pressure ulcer development in this cohort. Perioperative nurses play an important role in identifying existing or new pressure injuries. However, many of these nurses are unfamiliar with pressure ulcer classification, so education in this area is essential. Although the incidence of surgically acquired pressure ulcers was low in this cohort, careful skin inspection before and after surgery provides an opportunity for early treatment and may prevent existing lesions progressing to higher stages.

ACTIVITY AND Vp/Vs RATIO OF VOLCANO-TECTONIC SEISMIC SWARM ZONES AT NEVADO DEL RUIZ VOLCANO, COLOMBIA

Directory of Open Access Journals (Sweden)

Londoño B. John Makario

2010-06-01

Full Text Available An analysis of the seismic activity for volcano-tectonic earthquake (VT swarms zones at Nevado del Ruiz Volcano (NRV was carried out for the interval 1985- 2002, which is the most seismic active period at NRV until now (2010. The swarm-like seismicity of NRV was frequently concentrated in very well defined clusters around the volcano. The seismic swarm zone located at the active crater was the most active during the entire time. The seismic swarm zone located to the west of the volcano suggested some relationship with the volcanic crises. It was active before and after the two eruptions occurred in November 1985 and September 1989. It is believed that this seismic activity may be used as a monitoring tool of volcanic activity. For each seismic swarm zone the Vp/Vs ratio was also calculated by grouping of earthquakes and stations. It was found that each seismic swarm zone had a distinct Vp/Vs ratio with respect to the others, except for the crater and west swarm zones, which had the same value. The average Vp/Vs ratios for the seismic swarm zones located at the active crater and to the west of the volcano are about 6-7% lower than that for the north swarm zone, and about 3% lower than that for the south swarm zone. We suggest that the reduction of the Vp/Vs ratio is due to degassing phenomena inside the central and western earthquake swarm zones, or due to the presence of microcracks inside the volcano. This supposition is in agreement with other studies of geophysics, geochemistry and drilling surveys carried out at NRV.

The Evolution of Galápagos Volcanoes: An Alternative Perspective

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Karen S. Harpp

2018-05-01

Full Text Available The older eastern Galápagos are different in almost every way from the historically active western Galápagos volcanoes. Geochemical, geologic, and geophysical data support the hypothesis that the differences are not evolutionary, but rather the eastern volcanoes grew in a different tectonic environment than the younger volcanoes. The western Galápagos volcanoes have steep upper slopes and are topped by large calderas, whereas none of the older islands has a caldera, an observation that is supported by recent gravity measurements. Most of the western volcanoes erupt evolved basalts with an exceedingly small range of Mg#, Lan/Smn, and Smn/Ybn. This is attributed to homogenization in a crustal-scale magmatic mush column, which is maintained in a thermochemical steady state, owing to high magma supply directly over the Galápagos mantle plume. In contrast, the eastern volcanoes erupt relatively primitive magmas, with a large range in Mg#, Lan/Smn, and Smn/Ybn. These differences are attributed to isolated, ephemeral magmatic plumbing systems supplied by smaller magmatic fluxes throughout their histories. Consequently, each batch of magma follows an independent course of evolution, owing to the low volume of supersolidus material beneath these volcanoes. The magmatic flux to Galápagos volcanoes negatively correlates to the distance to the Galápagos Spreading Center (GSC. When the ridge was close to the plume, most of the plume-derived magma was directed to the ridge. Currently, the active volcanoes are much farther from the GSC, thus most of the plume-derived magma erupts on the Nazca Plate and can be focused beneath the large young shields. We define an intermediate sub-province comprising Rabida, Santiago, and Pinzon volcanoes, which were most active about 1 Ma. They have all erupted dacites, rhyolites, and trachytes, similar to the dying stage of the western volcanoes, indicating that there was a relatively large volume of mush beneath them

Association between ulcer site and outcome in complicated peptic ulcer disease: a Danish nationwide cohort study.

Science.gov (United States)

Lolle, Ida; Møller, Morten Hylander; Rosenstock, Steffen Jais

2016-10-01

Mortality rates in complicated peptic ulcer disease are high. This study aimed to examine the prognostic importance of ulcer site in patients with peptic ulcer bleeding (PUB) and perforated peptic ulcer (PPU). a nationwide cohort study with prospective and consecutive data collection. all patients treated for PUB and PPU at Danish hospitals between 2003 and 2014. demographic and clinical data reported to the Danish Clinical Registry of Emergency Surgery. 90- and 30-d mortality and re-intervention. the crude and adjusted association between ulcer site (gastric and duodenal) and the outcome measures of interest were assessed by binary logistic regression analysis. Some 20,059 patients with PUB and 4273 patients with PPU were included; 90-d mortality was 15.3% for PUB and 29.8% for PPU; 30-d mortality was 10.2% and 24.7%, respectively. Duodenal bleeding ulcer, as compared to gastric ulcer (GU), was associated with a significantly increased risk of all-cause mortality within 90 and 30 d, and with re-intervention: adjusted odds ratio (OR) 1.47 (95% confidence interval 1.30-1.67); p ulcers (DUs) in PPU patients: adjusted OR 0.99 (0.84-1.16); p = 0.698, OR 0.93 (0.78 to 1.10); p = 0.409, and OR 0.97 (0.80-1.19); p = 0.799, respectively. DU site is a significant predictor of death and re-intervention in patients with PUB, as compared to GU site. This does not seem to be the case for patients with PPU.

Giant lower oesophageal ulcer Bushman baby

African Journals Online (AJOL)

1983-02-26

Feb 26, 1983 ... The case of a giant, penetrating lower oesophageal ulcer in a 14-month-old Bushman baby is reported. This would probably be classified as a Barrett's ulcer. Histological examination showed that the ulcer developed in columnar epithelium and that there was normal stratified squamous oesophageal.

Peptic Ulcer Disease in Bangladesh: A Multi-centre Study.

Science.gov (United States)

Ghosh, C K; Khan, M R; Alam, F; Shil, B C; Kabir, M S; Mahmuduzzaman, M; Das, S C; Masud, H; Roy, P K

2017-01-01

The incidence of peptic ulcer has steadily declined through out the world. This decreasing trend is also noticeable in this subcontinent. The point prevalence of peptic ulcer (PUD) in Bangladesh was around 15% in eighties. The aim of this study was to see the present prevalence of peptic ulcer at endoscopy and to identify changing trends in the occurrence of peptic ulcer in Bangladesh. This retrospective analysis of the endoscopic records of multiple tertiary referral centres of Dhaka city were done from January 2012 to July 2013. A total of 5608 subjects were the study samples. We included those patients having peptic ulcer in the form of duodenal ulcer, benign gastric ulcer including pre-pyloric ulcer and gastric outlet obstruction due to peptic ulcer. Duodenal ulcer and benign gastric ulcer were found in 415(7.4%) and 184(3.28%) patients respectively and gastric outlet obstruction due to peptic ulcer was found in 23(0.40%) patients.

A Hydroxyurea-induced Leg Ulcer

OpenAIRE

Hwang, Seon-Wook; Hong, Soon-Kwon; Kim, Sang-Hyun; Seo, Jong-Keun; Lee, Deborah; Sung, Ho-Suk

2009-01-01

Hydroxyurea is a cytostatic agent that has recently become the drug of choice in the treatment of various myeloproliferative diseases. The cutaneous side effects of hydroxyurea include xerosis, hyperpigmentation, nail discoloration, and scaling. Leg ulcers have only rarely been reported in association with hydroxyurea treatment. A 75-year-old woman presented with leg ulcers, nail discoloration, and xerosis. The leg ulcers were refractory to conventional treatment. She had been taking oral hyd...

The Merapi Interactive Project: Offering a Fancy Cross-Disciplinary Scientific Understanding of Merapi Volcano to a Wide Audience.

Science.gov (United States)

Morin, J.; Kerlow, I.

2015-12-01

The Merapi volcano is of great interest to a wide audience as it is one of the most dangerous volcanoes worldwide and a beautiful touristic spot. The scientific literature available on that volcano both in Earth and Social sciences is rich but mostly inaccessible to the public because of the scientific jargon and the restricted database access. Merapi Interactive aims at developing clear information and attractive content about Merapi for a wide audience. The project is being produced by the Art and Media Group at the Earth Observatory of Singapore, and it takes the shape of an e-book. It offers a consistent, comprehensive, and jargon-filtered synthesis of the main volcanic-risk related topics about Merapi: volcanic mechanisms, eruptive history, associated hazards and risks, the way inhabitants and scientists deal with it, and what daily life at Merapi looks like. The project provides a background to better understand volcanoes, and it points out some interactions between scientists and society. We propose two levels of interpretation: one that is understandable by 10-year old kids and above and an expert level with deeper presentations of specific topics. Thus, the Merapi Interactive project intends to provide an engaging and comprehensive interactive book that should interest kids, adults, as well as Earth Sciences undergraduates and academics. Merapi Interactive is scheduled for delivery in mid-2016.

GLACIERS OF THE KORYAK VOLCANO

Directory of Open Access Journals (Sweden)

T. M. Manevich

2012-01-01

Full Text Available The paper presents main glaciological characteristics of present-day glaciers located on the Koryaksky volcano. The results of fieldwork (2008–2009 and high-resolution satellite image analysis let us to specify and complete information on modern glacial complex of Koryaksky volcano. Now there are seven glaciers with total area 8.36 km2. Three of them advance, two are in stationary state and one degrades. Moreover, the paper describes the new crater glacier.

Volcano geodesy in the Cascade arc, USA

Science.gov (United States)

Poland, Michael; Lisowski, Michael; Dzurisin, Daniel; Kramer, Rebecca; McLay, Megan; Pauk, Benjamin

2017-01-01

Experience during historical time throughout the Cascade arc and the lack of deep-seated deformation prior to the two most recent eruptions of Mount St. Helens might lead one to infer that Cascade volcanoes are generally quiescent and, specifically, show no signs of geodetic change until they are about to erupt. Several decades of geodetic data, however, tell a different story. Ground- and space-based deformation studies have identified surface displacements at five of the 13 major Cascade arc volcanoes that lie in the USA (Mount Baker, Mount St. Helens, South Sister, Medicine Lake, and Lassen volcanic center). No deformation has been detected at five volcanoes (Mount Rainier, Mount Hood, Newberry Volcano, Crater Lake, and Mount Shasta), and there are not sufficient data at the remaining three (Glacier Peak, Mount Adams, and Mount Jefferson) for a rigorous assessment. In addition, gravity change has been measured at two of the three locations where surveys have been repeated (Mount St. Helens and Mount Baker show changes, while South Sister does not). Broad deformation patterns associated with heavily forested and ice-clad Cascade volcanoes are generally characterized by low displacement rates, in the range of millimeters to a few centimeters per year, and are overprinted by larger tectonic motions of several centimeters per year. Continuous GPS is therefore the best means of tracking temporal changes in deformation of Cascade volcanoes and also for characterizing tectonic signals so that they may be distinguished from volcanic sources. Better spatial resolution of volcano deformation can be obtained through the use of campaign GPS, semipermanent GPS, and interferometric synthetic aperture radar observations, which leverage the accumulation of displacements over time to improve signal to noise. Deformation source mechanisms in the Cascades are diverse and include magma accumulation and withdrawal, post-emplacement cooling of recent volcanic deposits, magmatic

Volcano geodesy in the Cascade arc, USA

Science.gov (United States)

Poland, Michael P.; Lisowski, Michael; Dzurisin, Daniel; Kramer, Rebecca; McLay, Megan; Pauk, Ben

2017-08-01

Experience during historical time throughout the Cascade arc and the lack of deep-seated deformation prior to the two most recent eruptions of Mount St. Helens might lead one to infer that Cascade volcanoes are generally quiescent and, specifically, show no signs of geodetic change until they are about to erupt. Several decades of geodetic data, however, tell a different story. Ground- and space-based deformation studies have identified surface displacements at five of the 13 major Cascade arc volcanoes that lie in the USA (Mount Baker, Mount St. Helens, South Sister, Medicine Lake, and Lassen volcanic center). No deformation has been detected at five volcanoes (Mount Rainier, Mount Hood, Newberry Volcano, Crater Lake, and Mount Shasta), and there are not sufficient data at the remaining three (Glacier Peak, Mount Adams, and Mount Jefferson) for a rigorous assessment. In addition, gravity change has been measured at two of the three locations where surveys have been repeated (Mount St. Helens and Mount Baker show changes, while South Sister does not). Broad deformation patterns associated with heavily forested and ice-clad Cascade volcanoes are generally characterized by low displacement rates, in the range of millimeters to a few centimeters per year, and are overprinted by larger tectonic motions of several centimeters per year. Continuous GPS is therefore the best means of tracking temporal changes in deformation of Cascade volcanoes and also for characterizing tectonic signals so that they may be distinguished from volcanic sources. Better spatial resolution of volcano deformation can be obtained through the use of campaign GPS, semipermanent GPS, and interferometric synthetic aperture radar observations, which leverage the accumulation of displacements over time to improve signal to noise. Deformation source mechanisms in the Cascades are diverse and include magma accumulation and withdrawal, post-emplacement cooling of recent volcanic deposits, magmatic

Pouch failures following ileal pouch-anal anastomosis for ulcerative colitis

DEFF Research Database (Denmark)

Mark-Christensen, A; Erichsen, R; Brandsborg, S

2018-01-01

BACKGROUND: The ileal pouch-anal anastomosis is a procedure offered to patients with ulcerative colitis who opt for restoration of bowel continuity. The aim of this study was to determine the risk of pouch failure and ascertain risk factors associated with failure. METHOD: 1,991 patients with ulc......BACKGROUND: The ileal pouch-anal anastomosis is a procedure offered to patients with ulcerative colitis who opt for restoration of bowel continuity. The aim of this study was to determine the risk of pouch failure and ascertain risk factors associated with failure. METHOD: 1,991 patients......-anal anastomosis from Denmark, where pouch surgery is centralized, females had a higher risk of pouch failure. Of modifiable factors, low hospital volume and non-diversion were associated with a higher risk of pouch failure. This article is protected by copyright. All rights reserved....

Pressure ulcers: Back to the basics.

Science.gov (United States)

Agrawal, Karoon; Chauhan, Neha

2012-05-01

Pressure ulcer in an otherwise sick patient is a matter of concern for the care givers as well as the medical personnel. A lot has been done to understand the disease process. So much so that USA and European countries have established advisory panels in their respective continents. Since the establishment of these organizations, the understanding of the pressure ulcer has improved significantly. The authors feel that the well documented and well publicized definition of pressure ulcer is somewhat lacking in the correct description of the disease process. Hence, a modified definition has been presented. This disease is here to stay. In the process of managing these ulcers the basic pathology needs to be understood well. Pressure ischemia is the main reason behind the occurrence of ulceration. Different extrinsic and intrinsic factors have been described in detail with review of literature. There are a large number of risk factors causing ulceration. The risk assessment scales have eluded the surgical literature and mostly remained in nursing books and websites. These scales have been reproduced for completion of the basics on decubitus ulcer. The classification of the pressure sores has been given in a comparative form to elucidate that most of the classifications are the same except for minor variations. The management of these ulcers is ever evolving but the age old saying of "prevention is better than cure" suits this condition the most.

Pressure ulcers: Back to the basics

Directory of Open Access Journals (Sweden)

Karoon Agrawal

2012-01-01

Full Text Available Pressure ulcer in an otherwise sick patient is a matter of concern for the care givers as well as the medical personnel. A lot has been done to understand the disease process. So much so that USA and European countries have established advisory panels in their respective continents. Since the establishment of these organizations, the understanding of the pressure ulcer has improved significantly. The authors feel that the well documented and well publicized definition of pressure ulcer is somewhat lacking in the correct description of the disease process. Hence, a modified definition has been presented. This disease is here to stay. In the process of managing these ulcers the basic pathology needs to be understood well. Pressure ischemia is the main reason behind the occurrence of ulceration. Different extrinsic and intrinsic factors have been described in detail with review of literature. There are a large number of risk factors causing ulceration. The risk assessment scales have eluded the surgical literature and mostly remained in nursing books and websites. These scales have been reproduced for completion of the basics on decubitus ulcer. The classification of the pressure sores has been given in a comparative form to elucidate that most of the classifications are the same except for minor variations. The management of these ulcers is ever evolving but the age old saying of "prevention is better than cure" suits this condition the most.

Pressure ulcers: Back to the basics

Science.gov (United States)

Agrawal, Karoon; Chauhan, Neha

2012-01-01

Pressure ulcer in an otherwise sick patient is a matter of concern for the care givers as well as the medical personnel. A lot has been done to understand the disease process. So much so that USA and European countries have established advisory panels in their respective continents. Since the establishment of these organizations, the understanding of the pressure ulcer has improved significantly. The authors feel that the well documented and well publicized definition of pressure ulcer is somewhat lacking in the correct description of the disease process. Hence, a modified definition has been presented. This disease is here to stay. In the process of managing these ulcers the basic pathology needs to be understood well. Pressure ischemia is the main reason behind the occurrence of ulceration. Different extrinsic and intrinsic factors have been described in detail with review of literature. There are a large number of risk factors causing ulceration. The risk assessment scales have eluded the surgical literature and mostly remained in nursing books and websites. These scales have been reproduced for completion of the basics on decubitus ulcer. The classification of the pressure sores has been given in a comparative form to elucidate that most of the classifications are the same except for minor variations. The management of these ulcers is ever evolving but the age old saying of “prevention is better than cure” suits this condition the most. PMID:23162223

Immunological evaluation of captive green sea turtle (Chelonia mydas) with ulcerative dermatitis

Science.gov (United States)

Muñoz, Fernando Alberto; Estrada-Parra, Sergio; Romero-Rojas, Andrés; Gonzalez-Ballesteros, Erik; Work, Thierry M.; Villaseñor-Gaona, Hector; Estrada-Garcia, Iris

2013-01-01

Ulcerative dermatitis (UD) is common in captive sea turtles and manifests as skin erosions and ulcers associated with gram-negative bacteria. This study compared clinically healthy and UD-affected captive turtles by evaluating hematology, histopathology, immunoglobulin levels, and delayed-type hypersensitivity assay. Turtles with UD had significantly lower weight, reduced delayed-type hypersensitivity (DTH) responses, and higher heterophil:lymphocyte ratios. This study is the first to assay DTH in green turtles (Chelonia mydas) and suggests that UD is associated with immunosuppression.

Location-dependent depth and undermining formation of pressure ulcers.

Science.gov (United States)

Takahashi, Yoshiko; Isogai, Zenzo; Mizokami, Fumihiro; Furuta, Katsunori; Nemoto, Tetsuya; Kanoh, Hiroyuki; Yoneda, Masahiko

2013-08-01

We examined the location-specific properties of pressure ulcers, focusing on depth and undermining formation, which are often unfavorable factors for ulcer healing. We conducted a retrospective observational study of 2 independent databases on pressure ulcers. Databases from a 200-bed hospital (database A) and a 300-bed hospital (database B) were collected during different time periods. Relationships between ulcer location, ulcer depth, and undermining formation were analyzed. All pressure ulcers were accurately diagnosed and classified according to their locations. A total of 282 pressure ulcers in 189 patients from database A and 232 pressure ulcers in 154 patients from database B were analyzed. It was found that pressure ulcers primarily developed over the sacrum. Ratio of stages III and IV pressure ulcers was high in pressure ulcers of the foot, ankle, and crus on the lower leg. Among the deep pressure ulcers, undermining formation was frequently observed on the greater trochanter, ilium, and sacrum. In contrast, pressure ulcers of the foot, ankle, and crus did not exhibit undermining formation. Our results revealed marked differences in pressure ulcer properties depending on their location. Factors affecting depth and undermining of pressure ulcers appear to be related to anatomical and physical properties of the bone and subcutaneous tissue. Copyright © 2013 Tissue Viability Society. Published by Elsevier Ltd. All rights reserved.

Three-dimensional stochastic adjustment of volcano geodetic network in Arenal volcano, Costa Rica

Science.gov (United States)

Muller, C.; van der Laat, R.; Cattin, P.-H.; Del Potro, R.

2009-04-01

Volcano geodetic networks are a key instrument to understanding magmatic processes and, thus, forecasting potentially hazardous activity. These networks are extensively used on volcanoes worldwide and generally comprise a number of different traditional and modern geodetic surveying techniques such as levelling, distances, triangulation and GNSS. However, in most cases, data from the different methodologies are surveyed, adjusted and analysed independently. Experience shows that the problem with this procedure is the mismatch between the excellent correlation of position values within a single technique and the low cross-correlation of such values within different techniques or when the same network is surveyed shortly after using the same technique. Moreover one different independent network for each geodetic surveying technique strongly increase logistics and thus the cost of each measurement campaign. It is therefore important to develop geodetic networks which combine the different geodetic surveying technique, and to adjust geodetic data together in order to better quantify the uncertainties associated to the measured displacements. In order to overcome the lack of inter-methodology data integration, the Geomatic Institute of the University of Applied Sciences of Western Switzerland (HEIG-VD) has developed a methodology which uses a 3D stochastic adjustment software of redundant geodetic networks, TRINET+. The methodology consists of using each geodetic measurement technique for its strengths relative to other methodologies. Also, the combination of the measurements in a single network allows more cost-effective surveying. The geodetic data are thereafter adjusted and analysed in the same referential frame. The adjustment methodology is based on the least mean square method and links the data with the geometry. Trinet+ also allows to run a priori simulations of the network, hence testing the quality and resolution to be expected for a determined network even

Ulcerative colitis masked by giant urticaria.

Science.gov (United States)

Caroselli, C; Plocco, M; Pratticò, F; Bruno, C; Antonaglia, C; Rota, F; Curreli, I; Caroselli, A; Bruno, G

2007-01-01

The occurrence of giant urticaria and ulcerative colitis is very infrequent. A 23 year-old female reported the initial eruption of short-lived cutaneous itchy weals on her arms. Then lesions ran together and became confluent, extending to her legs, followed by undefined abdominal pain and a slight increase of body temperature. Exams showed hystologically confirmed ulcerative colitis, with perinuclear anti-neutrophil cytoplasmic antibody positivity. Ulcerative colitis therapy led not only to the remission of the colitic symptoms, but also to the prompt recovery of skin manifestations. Urticaria was the epiphenomenon of ulcerative colitis.

Sustained compression and healing of chronic venous ulcers.

Science.gov (United States)

Blair, S. D.; Wright, D. D.; Backhouse, C. M.; Riddle, E.; McCollum, C. N.

1988-01-01

STUDY OBJECTIVE--Comparison of four layer bandage system with traditional adhesive plaster bandaging in terms of (a) compression achieved and (b) healing of venous ulcers. DESIGN--Part of larger randomised trial of five different dressings. SETTING--Outpatient venous ulcer clinic in university hospital. PATIENTS--(a) Pressure exerted by both bandage systems was measured in the same 20 patients. (b) Healing with the four layer bandage was assessed in 148 legs in 126 consecutive patients (mean age 71 (SE 2); range 30-96) with chronic venous ulcers that had resisted treatment with traditional bandaging for a mean of 27.2 (SE 8) months. INTERVENTIONS--(a) Four layer bandage system or traditional adhesive plaster bandaging for pressure studies; (b) four layer bandaging applied weekly for studies of healing. END POINTS--(a) Comparison of pressures achieved at the ankle for up to one week; (b) complete healing within 12 weeks. MEASUREMENTS AND MAIN RESULTS--(a) Four layer bandage produced higher initial pressures at the ankle of 42.5 (SE 1) mm Hg compared with 29.8 (1.8) for the adhesive plaster (p less than 0.001; 95% confidence interval 18.5 to 6.9). Pressure was maintained for one week with the four layer bandage but fell to 10.4 (3.5) mm Hg at 24 hours with adhesive plaster bandaging. (b) After weekly bandaging with the four layer bandage 110 of 48 venous ulcers had healed completely within 12 (mean 6.3 (0.4)) weeks. CONCLUSION--Sustained compression of over 40 mm Hg achieved with a multilayer bandage results in rapid healing of chronic venous ulcers that have failed to heal in many months of compression at lower pressures with more conventional bandages. PMID:3144330

Contact Lens Related Corneal Ulcer

OpenAIRE

Loh, KY; Agarwal, P

2010-01-01

A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns is the increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specific instruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are: overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. Th...

The 2008 Eruption of Chaitén Volcano, Chile and National Volcano-Monitoring Programs in the U.S. and Chile

Science.gov (United States)

Ewert, J. W.; Lara, L. E.; Moreno, H.

2008-12-01

Chaitén volcano, southern Chile, began erupting on 2 May 2008. The eruption produced 3 Plinian eruption pulses between May 2 and 8. Between Plinian phases the volcano emitted a constant column of ash to approximately 10 km, gradually diminishing to approximately 3 km by the end of June. The eruption of Chaitén was remarkable on several counts--it was the first rhyolite eruption on the planet since Novarupta (Katmai) erupted in 1912, and Chaitén had apparently lain dormant for approximately 9300 years. Though Chaitén is located in a generally sparsely populated region, the eruption had widespread impacts. More than 5000 people had to be quickly evacuated from proximal areas and aviation in southern South America was disrupted for weeks. Within 10 days secondary lahars had overrun much of the town of Chaitén complicating the prospects of the townspeople to return to their homes. Prior to the eruption onset, the nearest real-time seismic station was 300 km distant, and earthquakes were not felt by local citizens until approximately 30 hours before the eruption onset. No other signs of unrest were noted. Owing to the lack of near-field monitoring, and the nighttime eruption onset, there was initial confusion about which volcano was erupting: Chaitén or nearby Michinmahuida. Lack of monitoring systems at Chaitén meant that warning time for the public at risk was extremely short, and owing to the nature of the eruption and the physical geography of the area, it was very difficult to install monitoring instruments to track its progress after the eruption started. The lack of geophysical monitoring also means that an important data set on precursory behavior for silicic systems was not collected. With more than 120 Pleistocene to Holocene-age volcanoes within its continental territory, Chile is one of the more volcanically active countries in the world. The eruption of Chaitén has catalyzed the creation of a new program within the Servicio Nacional de Geología y

Pressure ulcers and their associated factors in nursing home inmates

International Nuclear Information System (INIS)

Akea, N.K.

2015-01-01

To assess pressure ulcers and the associated risk factors, among the individuals who stayed at Yozgat Rehabilitation Care Center in Turkey. Study Design: A descriptive study. Place and Duration of Study: Yozgat Rehabilitation Care Center, Turkey, from August to September 2011. Methodology: One hundred and seventy five individuals participated in the study who received care at the above nursing home and agreed to participate in the study. The data were collected with an information form of descriptive characteristics (the form included a total of 15 questions asked to get information about socio-demographic characteristics) and Braden risk assessment scale. For the data evaluation, Mann-Whitney U-test, Krushall-Wallis Variance analysis, Logistic Regression analysis were used. Statistical significance was defined by a probability level of p < 0.05. Results: The mean score of Braden risk assessment scale of the individuals was 15.0 +- 3.3 and 16.0% were under very high risk. Nine (5.1%) had pressure ulcers. The average duration of stay was 2.17 +- 0.80 years. Participants who were underweight, had lived at the rehabilitation center for a longer time, and were fed on regime 1, had a higher risk of developing pressure ulcers (p < 0.001). Conclusion: Individuals who stayed in nursing home were under very high risk of pressure ulcer. Pressure ulcers are preventable by the elimination of some risk factors and good nursing care. Such individuals should be periodically assessed in terms of risk. (author)

A Controversial Source for a 1.2-1.5 km3 Debris Avalanche Deposit in Northern Ecuador: A Case Study of Cubilche Volcano

Science.gov (United States)

Mulas, M.; Bowman, L.; Roverato, M.; Larrea Marquez, P.; Casado, I.

2017-12-01

Debris avalanche deposits (DAD) are common products of catastrophic volcanic edifice collapses. These failure events leave peculiar horseshoe-shaped scars on the summits of stratovolcanoes. Cubilche Volcano (3826 masl), located S of the city of Ibarra (Imbabura Province) and E of the dormant Imbabura volcano, displays a distinct horseshoe-shaped scar towards the N. This post-collapse edifice that we name "Old Cubilche Volcano" (OCV) hosts an additional edifice, "Young Cubilche Volcano" (YCV), which partially covers the southern flank of OCV. Knowledge of Cubilche is critical because of its close proximity to the provincial capital of Ibarra. In fact, Imbabura edifice was built over the northwestern slope of OCV and partially covered it. The studied DAD (unknown age) has been recently linked to Imbabura Volcano as a product of its northwestern sector collapse (LePennec et al., 2011). Alternatively, previous work proposed that the DAD, covering 80 km2 and reaching >13 km distance with an estimated volume of 1.6 km3, was the product of the older OCV (Ruiz, 2003). To constrain the source of the DAD, detailed fieldwork with granulometric, petrological, and geochemical analyses of the deposit was conducted. Preliminary data points to Cubilche as the most likely source for this DAD in accordance with Ruiz (2003). The shaded relief image of the present day OCV shows that the morphology of the volcano is well-preserved on its southern, eastern, and western flanks. This allows the reconstruction of the morphology of OCV prior to the collapse through interpolation of elevation and altitude data of the preserved flanks. A DEM of the present day topography (12m horizontal resolution) obtained from TanDEM-X data was used for extrapolating the morphology. This methodology shows that the post-collapse base of the amphitheater was reconstructed by removing the relief of the present day YCV. The reconstructed topography of OCV shows that it could have been a symmetric cone, reaching

Mount Meager Volcano, Canada: a Case Study for Landslides on Glaciated Volcanoes

Science.gov (United States)

Roberti, G. L.; Ward, B. C.; van Wyk de Vries, B.; Falorni, G.; Perotti, L.; Clague, J. J.

2015-12-01

Mount Meager is a strato-volcano massif in the Northern Cascade Volcanic Arc (Canada) that erupted in 2350 BP, the most recent in Canada. To study the stability of the Massif an international research project between France ( Blaise Pascal University), Italy (University of Turin) and Canada (Simon Fraser University) and private companies (TRE - sensing the planet) has been created. A complex history of glacial loading and unloading, combined with weak, hydrothermally altered rocks has resulted in a long record of catastrophic landslides. The most recent, in 2010 is the third largest (50 x 106 m3) historical landslide in Canada. Mount Meager is a perfect natural laboratory for gravity and topographic processes such as landslide activity, permafrost and glacial dynamics, erosion, alteration and uplift on volcanoes. Research is aided by a rich archive of aerial photos of the Massif (1940s up to 2006): complete coverage approximately every 10 years. This data set has been processed and multi-temporal, high resolution Orthophoto and DSMs (Digital Surface Models) have been produced. On these digital products, with the support on field work, glacial retreat and landslide activity have been tracked and mapped. This has allowed for the inventory of unstable areas, the identification of lava flows and domes, and the general improvement on the geologic knowledge of the massif. InSAR data have been used to monitor the deformation of the pre-2010 failure slope. It will also be used to monitor other unstable slopes that potentially can evolve to catastrophic collapses of up to 1 km3 in volume, endangering local communities downstream the volcano. Mount Meager is definitively an exceptional site for studying the dynamics of a glaciated, uplifted volcano. The methodologies proposed can be applied to other volcanic areas with high erosion rates such as Alaska, Cascades, and the Andes.

Ulcers

Science.gov (United States)

... of the stomach and intestines. In certain circumstances stress can help cause ulcers. But this usually only happens when illness involving severe emotional or physical stress is involved — such as when someone too sick ...

Ulcers

Science.gov (United States)

... These include both regular and decaffeinated coffee, tea, chocolate, meat extracts, alcohol, black pepper, chili powder, mustard ... Disease, peptic ulcers, proton pump inhibitor, sucralfate, triple therapy January 1, 1996 Copyright © American Academy of Family ...

Pulmonary hypertension in patients with Martorell hypertensive leg ulcer: a case control study

Science.gov (United States)

2012-01-01

Background Martorell hypertensive ischemic leg ulcer (Martorell ulcer) is characterized by distinct alterations in the arteriolar wall of subcutaneous vessels, leading to progressive narrowing of the vascular lumen and increase of vascular resistance. These changes are similar to the alterations observed in pulmonary arterioles in patients with chronic pulmonary hypertension (PH). This study was aimed to assess an association between the two disorders. Methods In this case–control study, 14 patients with Martorell ulcer were clinically assessed for the presence of pulmonary hypertension using transthoracic Doppler echocardiography. Data from patients were compared to 28 matched hypertensive controls. Results Systolic pulmonary arterial pressure (sPAP) in patients with Martorell ulcer was significantly higher than in the control group (33.8 ± 16.9 vs 25.3 ± 6.5 mmHg, p = 0.023); the prevalence of pulmonary hypertension was 31% (5/14) in patients and 7% (2/28) in controls (p = 0.031). No differences were seen in left heart size and function between patients and controls. Conclusion This study provides first evidence that subcutaneous arteriolosclerosis, the hallmark of Martorell ulcer, is associated with PH. These findings suggest that patients with Martorell leg ulcer might be at significant risk to develop elevated pulmonary arterial pressure. Patients with leg ulcers who present with dyspnea should be evaluated by echocardiography for the presence of pulmonary hypertension. PMID:22686459

Helical CT findings of gastric wall thickening by peptic ulcer : compared with gastric adenocarcinoma with ulcer

International Nuclear Information System (INIS)

Jung, Won Jung; Choi, Jong Chul; Seo, Keum Soo; Koo, Bon Sik; Park, Byeong Ho; Kim, Chung Ku; Lee, Ki Nam; Nam, Kyung Jin

2000-01-01

To compare on the basis of helical CT findings gastric wall thickening of peptic gastric ulcer with that of gastric adenocarcinoma with ulcer. Thirty-eight patients with pathologically proven gastric lesion (17 cases of peptic ulcer and 21 cases of ulcerative or ulceroinfiltrative gastric cancer (Borrman type II, III) underwent helical CT, and the findings were retrospectively reviewed in terms of maximum abnormal wall thickness, preservation of the inner enhancing layer, the presence three discriminate layers of gastric wall, and enhancement pattern. The enhancement pattern of abnormally thick wall was compared with that of the portal phase of back muscle, and was defined as low, iso, or high. The Chi-square test and Student t test were used for statistical analysis. In cases of peptic ulcer and gastric cancer with ulceration, maximum abnormal wall thickness was 7-30 (mean, 16.1)mm, and 11-33 (mean, 21.8)mm, respectively. The inner enhancing layer was preserved in 15 of 17 patients (88.2%) and one of 21 (4.8%); three discriminate layers of gastric wall were observed in 8 of 17 patients (47.0%), and one of 21 (4.8%). The enhancement pattern was low in 12 of 17 patients (70.5%), and 3 of 21 (14.3%); iso in 4 of 17 (23.5%), and 4 of 21 (19.0%), and high in one of 17 (5.9%), and 14 of 21 (66.7%). All figures refer, respectively, to the two distinct conditions. In terms of preservation of the inner enhancing layer, three discriminate layers of gastric wall, and a low enhancement pattern, there were statistically significant differences between peptic ulcer and gastric adenocarcinoma with ulcer. Where the enhancement was high, however, the statistically significant difference between the two conditions was even greater. There was no statistically significant difference in terms of gastric wall thickness or iso-attenuation of thickened gastric. Helical CT findings of gastric wall thickening, preservation of the inner enhancing layer, and three discriminate layers of

Helical CT findings of gastric wall thickening by peptic ulcer : compared with gastric adenocarcinoma with ulcer

Energy Technology Data Exchange (ETDEWEB)

Jung, Won Jung; Choi, Jong Chul; Seo, Keum Soo; Koo, Bon Sik; Park, Byeong Ho; Kim, Chung Ku; Lee, Ki Nam; Nam, Kyung Jin [College of Medicine, Dong A University, Pusan (Korea, Republic of)

2000-02-01

To compare on the basis of helical CT findings gastric wall thickening of peptic gastric ulcer with that of gastric adenocarcinoma with ulcer. Thirty-eight patients with pathologically proven gastric lesion (17 cases of peptic ulcer and 21 cases of ulcerative or ulceroinfiltrative gastric cancer (Borrman type II, III)) underwent helical CT, and the findings were retrospectively reviewed in terms of maximum abnormal wall thickness, preservation of the inner enhancing layer, the presence three discriminate layers of gastric wall, and enhancement pattern. The enhancement pattern of abnormally thick wall was compared with that of the portal phase of back muscle, and was defined as low, iso, or high. The Chi-square test and Student t test were used for statistical analysis. In cases of peptic ulcer and gastric cancer with ulceration, maximum abnormal wall thickness was 7-30 (mean, 16.1)mm, and 11-33 (mean, 21.8)mm, respectively. The inner enhancing layer was preserved in 15 of 17 patients (88.2%) and one of 21 (4.8%); three discriminate layers of gastric wall were observed in 8 of 17 patients (47.0%), and one of 21 (4.8%). The enhancement pattern was low in 12 of 17 patients (70.5%), and 3 of 21 (14.3%); iso in 4 of 17 (23.5%), and 4 of 21 (19.0%), and high in one of 17 (5.9%), and 14 of 21 (66.7%). All figures refer, respectively, to the two distinct conditions. In terms of preservation of the inner enhancing layer, three discriminate layers of gastric wall, and a low enhancement pattern, there were statistically significant differences between peptic ulcer and gastric adenocarcinoma with ulcer. Where the enhancement was high, however, the statistically significant difference between the two conditions was even greater. There was no statistically significant difference in terms of gastric wall thickness or iso-attenuation of thickened gastric. Helical CT findings of gastric wall thickening, preservation of the inner enhancing layer, and three discriminate layers of

Body Wave and Ambient Noise Tomography of Makushin Volcano, Alaska

Science.gov (United States)

Lanza, F.; Thurber, C. H.; Syracuse, E. M.; Ghosh, A.; LI, B.; Power, J. A.

2017-12-01

Located in the eastern portion of the Alaska-Aleutian subduction zone, Makushin Volcano is among the most active volcanoes in the United States and has been classified as high threat based on eruptive history and proximity to the City of Unalaska and international air routes. In 2015, five individual seismic stations and three mini seismic arrays of 15 stations each were deployed on Unalaska island to supplement the Alaska Volcano Observatory (AVO) permanent seismic network. This temporary array was operational for one year. Taking advantage of the increased azimuthal coverage and the array's increased earthquake detection capability, we developed body-wave Vp and Vp/Vs seismic images of the velocity structure beneath the volcano. Body-wave tomography results show a complex structure with the upper 5 km of the crust dominated by both positive and negative Vp anomalies. The shallow high-Vp features possibly delineate remnant magma pathways or conduits. Low-Vp regions are found east of the caldera at approximately 6-9 km depth. This is in agreement with previous tomographic work and geodetic models, obtained using InSAR data, which had identified this region as a possible long-term source of magma. We also observe a high Vp/Vs feature extending between 7 and 12 km depth below the caldera, possibly indicating partial melting, although the resolution is diminished at these depths. The distributed stations allow us to further complement body-wave tomography with ambient noise imaging and to obtain higher quality of Vs images. Our data processing includes single station data preparation and station-pair cross-correlation steps (Bensen et al., 2007), and the use of the phase weighted stacking method (Schimmel and Gallart, 2007) to improve the signal-to-noise ratio of the cross-correlations. We will show surface-wave dispersion curves, group velocity maps, and ultimately a 3D Vs image. By performing both body wave and ambient noise tomography, we provide a high

[Health education for varicose ulcer patients through group activities].

Science.gov (United States)

da Silva, Jodo Luis Almeida; Lopes, Marta Julia Marques

2006-06-01

It is a report on the group activities carried out with carriers of varicose ulcer in a health unit in Porto Alegre, Rio Grande do Sul, Brazil. The varicose ulcer presents factors, besides the biological ones, which interfere in the cicatrization, in the relapse cases and in its effective resolution. The proposed activities aimed at producing behavior changes with the intention of achieving self-care, providing information, socializing the participants, and stimulating cooperation, searching for joint solutions, aggregating interdisciplinary spirit and improving the care. Two groups have been formed and a thematic schedule established. The results have showed higher adhesion to the treatment, behavioral changes, and adapted and more effective attitudes of the health team.

Development and Improvement of Simple Colonic Mucosal Ulcer during Treatment of Severe Ulcerative Colitis with Tacrolimus

Directory of Open Access Journals (Sweden)

Ayumi Ito

2017-03-01

Full Text Available Diarrhea, melena, and lower abdominal pain developed in a male in his 20s and colonoscopy showed pancolitis-type severe ulcerative colitis (UC. Treatment was initiated with 4,000 mg of 5-aminosalicylic acid and 60 mg/day of prednisolone, but the symptoms and inflammatory reaction worsened with prednisolone dose reduction. Tacrolimus was added to the treatment, which subsequently induced remission. Serial colonoscopies during the treatment showed improvement in ulcer and mucosal edema throughout the entire large intestine, but a new solitary round ulcer appeared at the end of the ileum. Since no signs of Behçet’s disease were noted, it was considered as a simple ulcer, a complication of UC. Tacrolimus treatment was continued based on continued improvement in clinical features and colonic mucosa, excluding the end of the ileum. Colonoscopy at 6 months after initiation of tacrolimus showed healing of the large intestinal mucosa, although mild congestion was still noted. The solitary round ulcer at the end of the ileum improved to a small erosion. We report the improvement of a simple ulcer that developed during tacrolimus treatment.

Radon emanometry in active volcanoes

Energy Technology Data Exchange (ETDEWEB)

Seidel, J.L.; Monnin, M. (CNRS, IN2P3, BP45/F63170 Aubiere (France)); Cejudo, J. (Instituto Nacional de Investigaciones Nucleares, Mexico City)

1984-01-01

Radon emission measurements from active volcanoes has, since 1981, been continuously measured at monitoring stations in Mexico and in Costa Rica. Counting of etched alpha tracks on cellulose nitrate LR-115 detectors give varying results at the several stations. Radon emanation at Chichon, where an explosive eruption occurred in 1982, fell down. Radon detection at the active volcano in Colima shows a pattern of very low emission. At the Costa Rica stations located at Poas, Arenal and Irazu, the radon emanation shows regularity.

Clinical observation of cryotherapy and amniotic membrane transplantation in the management of Fusarium corneal ulcer

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Qiong Xie

2014-10-01

Full Text Available AIM:To examine the efficacy and safety of cryotherapy in the management of Fusarium corneal ulcer. METHODS: Retrospective contract analysis of the clinical data of 41 patients(41 eyeswho infected with Fusarium corneal ulcer. All of them underwent focal lesion keratectomy combined with amniotic membrane transplantation between January 2010 and May 2013. The cryotherapy treatment group of 22 cases(22 eyes, non-cryotherapy group of 19 cases(19 eyes. All the cases were followed up for 3～12mo. We analyzed the healing of corneal ulcer, corneal neovascularization, postoperative visual acuity, complications and ulcer recurrences. RESULTS: There were no significant difference for the two groups at the cure rate and the recovery rate, the corneal neovascularization and postoperative visual acuity(P>0.05. The total effective rate and corneal healing time in cryotherapy group was significantly higher than that in non-cryotherapy group(PPCONCLUSION: Cryotherapy is an effective and safe method for the treatment of Fusarium corneal ulcer.

Risk perception at a persistently active volcano: warnings and trust at Popocatépetl volcano in Mexico, 2012-2014

Science.gov (United States)

Donovan, Amy; Ayala, Irasema Alcántara; Eiser, J. R.; Sparks, R. S. J.

2018-05-01

This paper presents data from an online survey carried out in Mexico from 2012 to 2014. The survey focussed on the risk to Mexico City from Popocatépetl, an active volcano 60 km from the city. During the time period, volcanic activity was variable, and the alert level changed accordingly. The survey showed that people surveyed at the higher alert level were generally more concerned about the volcano. Since these people were measured separately from those who responded at the lower alert level and yet self-reported on the same scale as more concerned, this provides a useful indicator that the raised alert level may be associated with higher risk perception, and that alert level systems act as boundary objects in the translation of scientific information. In general, trust in various groups was most strongly explained by the perceived knowledge of the groups, followed by their perceived motivation (whether or not they are viewed as working in society's interest), with accuracy a tertiary concern. Some respondents were anxious about false alarms—these people also tended to be concerned about scientific accuracy while those who favoured precaution tended to be more trusting. The perceived effectiveness of warning and evacuation plans was also a significant predictor for trust in official groups. In general, the results suggest that there are important links between trust, warning plans and the perceived motivation of particular groups as well as between trust and perceived knowledge.

BURULI ULCER THE (1)

African Journals Online (AJOL)

We report a 22 years old female patient from Southern Ethiopia with ulcerative form of Buruli ulcer on the left leg. The case suffered for more ... general, there is no difference in the infection rate among males and ... 'Department of Pediatrics and Child Health, College of Public Health and Medical Sciences, Jimma University.

Pressure Ulcer Surveillance in Neurotrauma Patients at a Level One Trauma Centre in India

Directory of Open Access Journals (Sweden)

Annu Babu

2015-11-01

Full Text Available Objectives: Pressure ulcers are a multifactorial, prevalent, and preventable morbidity. They cause a burden both financially and emotionally, to the individual, their family and doctor, and to society as a whole. Pressure ulcers are extremely difficult to treat; therefore, prevention is key. Methods: We started a Wound Care Surveillance Program in 2012 involving nurses, physiotherapists, and doctors. We intended to prevent the occurrence of pressure ulcers, ensure early detection, and facilitate the healing process. The Braden scale was used to stratify patients’ risk. The number of patients observed in our study was 2,974 over a one-year period. Results: The pressure sore prevalence was 3.1%. Younger and middle-aged patients were most commonly affected; 27% of these patients did not survive. Mortality was not attributed to the pressure ulcer directly. The most common mode of injury was road traffic accidents. Most of our patients had just a single pressure area affected, most commonly the sacrum. Most patients were managed with debridement and dressings while 12% received surgical treatment. Of those with stage one ulcers, 29% healed completely at two months. In stage two and three patients, 17% and 6% healed in two months, respectively, and this number was zero in stage four patients. Conclusion: The Wound Care Surveillance Program has been a very effective strategy for the prevention and management of pressure ulcers. Stage two ulcers were the most common in our setup. Braden scoring, traditionally used to screen these ulcers, can be used as a predictive and prognostic tool to predict healing of pressure ulcers. Poor healing is expected in higher staged ulcers and patients with spinal injury and major solid organ injury and those who need a tracheostomy. Home-based care is not up to mark in our society and accounts for most of the cases in the follow-up.

Relative chronology of Martian volcanoes

International Nuclear Information System (INIS)

Landheim, R.; Barlow, N.G.

1991-01-01

Impact cratering is one of the major geological processes that has affected the Martian surface throughout the planet's history. The frequency of craters within particular size ranges provides information about the formation ages and obliterative episodes of Martian geologic units. The Barlow chronology was extended by measuring small craters on the volcanoes and a number of standard terrain units. Inclusions of smaller craters in units previously analyzed by Barlow allowed for a more direct comparison between the size-frequency distribution data for volcanoes and established chronology. During this study, 11,486 craters were mapped and identified in the 1.5 to 8 km diameter range in selected regions of Mars. The results are summarized in this three page report and give a more precise estimate of the relative chronology of the Martian volcanoes. Also, the results of this study lend further support to the increasing evidence that volcanism has been a dominant geologic force throughout Martian history

Geophysical monitoring of the Purace volcano, Colombia

Directory of Open Access Journals (Sweden)

M. Arcila

1996-06-01

Full Text Available Located in the extreme northwestern part of the Los Coconucos volcanic chain in the Central Cordillera, the Purace is one of Colombia's most active volcanoes. Recent geological studies indicate an eruptive history of mainly explosive behavior which was marked most recently by a minor ash eruption in 1977. Techniques used to forecast the renewal of activity of volcanoes after a long period of quiescence include the monitoring of seismicity and ground deformation near the volcano. As a first approach toward the monitoring of the Purace volcano, Southwest Seismological Observatory (OSSO, located in the city of Cali, set up one seismic station in 1986. Beginning in June 1991, the seismic signals have also been transmitted to the Colombian Geological Survey (INGEOMINAS at the Volcanological and Seismological Observatory (OVS-UOP, located in the city of Popayan. Two more seismic stations were installed early in 1994 forming a minimum seismic network and a geodetic monitoring program for ground deformation studies was established and conducted by INGEOMINAS.

Helicobacter pylori and Peptic Ulcers

Centers for Disease Control (CDC) Podcasts

In this podcast, CDC's Dr. David Swerdlow discusses the relationship between Helicobacter pylori and peptic ulcer disease and trends in hospitalization rates for peptic ulcer disease in the United States between 1998 and 2005.

Therapeutics for Equine Gastric Ulcer Syndrome.

Science.gov (United States)

Zavoshti, Fereydon Rezazadeh; Andrews, Frank M

2017-04-01

Equine gastric ulcer syndrome (EGUS) is an umbrella term used to describe ulcers in the nonglandular squamous and glandular mucosa, terminal esophagus, and proximal duodenum. Gastric ulcers in the squamous and glandular regions occur more often than esophageal or duodenal ulcers and likely have a different pathogenesis. At present, omeprazole is accepted globally as the best pharmacologic therapy for both regions of the stomach; however, the addition of coating agents and synthetic prostaglandins could add to its effectiveness in treatment of EGUS. Dietary and environmental management are necessary for prevention of recurrence. Copyright © 2016 Elsevier Inc. All rights reserved.

Become the PPUPET Master: Mastering Pressure Ulcer Risk Assessment With the Pediatric Pressure Ulcer Prediction and Evaluation Tool (PPUPET).

Science.gov (United States)

Sterken, David J; Mooney, JoAnn; Ropele, Diana; Kett, Alysha; Vander Laan, Karen J

2015-01-01

Hospital acquired pressure ulcers (HAPU) are serious, debilitating, and preventable complications in all inpatient populations. Despite evidence of the development of pressure ulcers in the pediatric population, minimal research has been done. Based on observations gathered during quarterly HAPU audits, bedside nursing staff recognized trends in pressure ulcer locations that were not captured using current pressure ulcer risk assessment tools. Together, bedside nurses and nursing leadership created and conducted multiple research studies to investigate the validity and reliability of the Pediatric Pressure Ulcer Prediction and Evaluation Tool (PPUPET). Copyright © 2015 Elsevier Inc. All rights reserved.

Translating Volcano Hazards Research in the Cascades Into Community Preparedness

Science.gov (United States)

Ewert, J. W.; Driedger, C. L.

2015-12-01

Research by the science community into volcanic histories and physical processes at Cascade volcanoes in the states of Washington, Oregon, and California has been ongoing for over a century. Eruptions in the 20th century at Lassen Peak and Mount St. Helen demonstrated the active nature of Cascade volcanoes; the 1980 eruption of Mount St. Helens was a defining moment in modern volcanology. The first modern volcano hazards assessments were produced by the USGS for some Cascade volcanoes in the 1960s. A rich scientific literature exists, much of which addresses hazards at these active volcanoes. That said community awareness, planning, and preparation for eruptions generally do not occur as a result of a hazard analyses published in scientific papers, but by direct communication with scientists. Relative to other natural hazards, volcanic eruptions (or large earthquakes, or tsunami) are outside common experience, and the public and many public officials are often surprised to learn of the impacts volcanic eruptions could have on their communities. In the 1980s, the USGS recognized that effective hazard communication and preparedness is a multi-faceted, long-term undertaking and began working with federal, state, and local stakeholders to build awareness and foster community action about volcano hazards. Activities included forming volcano-specific workgroups to develop coordination plans for volcano emergencies; a concerted public outreach campaign; curriculum development and teacher training; technical training for emergency managers and first responders; and development of hazard information that is accessible to non-specialists. Outcomes include broader ownership of volcano hazards as evidenced by bi-national exchanges of emergency managers, community planners, and first responders; development by stakeholders of websites focused on volcano hazards mitigation; and execution of table-top and functional exercises, including evacuation drills by local communities.

A study of associations between gastric ulcers and the behaviour of finisher pigs

DEFF Research Database (Denmark)

Rutherford, Kenneth M.D.; Thompson, Carol S.; Thomson, Jill R.

2018-01-01

=26). Assessment of various predefined postures and behaviours was made by an observer blind to the gastric ulcer status of the observed pigs. Behavioural data from the two sites were combined in a single analysis. Pigs with gastric ulcers tended to spend less time idle (P=0.081) and less time lying...... on their left side (P=0.064), and significantly more time standing (P=0.009), or walking (P=0.038) compared to healthy pigs. Pigs with ulcers also showed an increased frequency of posture changes (P=0.02). A decrease in time spent lying on the left and an increase in standing/walking could both be interpreted...... as attempts to avoid liquid gastric contents pooling in the cranial region of the stomach. This along with the higher level of posture changes observed may indicate some degree of pain/discomfort associated with the presence of gastric ulcers in pigs. This study is the first to identify apparent behavioural...

Perforated peptic ulcer

DEFF Research Database (Denmark)

Søreide, Kjetil; Thorsen, Kenneth; Harrison, Ewen M

2015-01-01

Perforated peptic ulcer is a common emergency condition worldwide, with associated mortality rates of up to 30%. A scarcity of high-quality studies about the condition limits the knowledge base for clinical decision making, but a few published randomised trials are available. Although Helicobacter...... need further assessment. Adequate trials with low risk of bias are urgently needed to provide better evidence. We summarise the evidence for perforated peptic ulcer management and identify directions for future clinical research....

Incidence and risk factors associated with the development of pressure ulcers in an intensive care unit.

Science.gov (United States)

González-Méndez, María Isabel; Lima-Serrano, Marta; Martín-Castaño, Catalina; Alonso-Araujo, Inmaculada; Lima-Rodríguez, Joaquín Salvador

2018-03-01

To determinate the incidence, incidence rate and risk factors of pressure ulcers in critical care patients. Pressure ulcers represent one of the most frequent health problems in clinical practice. Specifically, critical patients who are hospitalised in intensive care units have a higher risk of developing a pressure ulcer, with an incidence that fluctuates between 3.3-39.3% according to previous studies. Prospective cohort study. Three hundred and thirty-five adult patients (over 18 years old) who were hospitalised in intensive care units for at least 24 hr were monitored for a maximum of 32 days. They were excluded if they had a pressure ulcers at admission. The survival rate for pressure ulcers, from stages I-IV, was calculated using the Kaplan-Meier method. A multivariate Cox regression model was adjusted to identify the main risk factors for pressure ulcers: demographic, clinical, prognostic and therapeutic variables. The incidence of pressure ulcers in critical patients was 8.1%, and the incidence rate was 11.72 pressure ulcers for 1,000 days of intensive care units stay; 40.6% of pressure ulcers were of stage I and 59.4% of stage II, mainly in the sacrum. According to the Cox model, the main risk factors for pressure ulcers were in-hospital complications, prognostic scoring system (SAPS III) and length of immobilisation. The incidence of pressure ulcers is lower than that shown in recent studies. Complications on the unit and the prognosis score were risk factors associated with pressure ulcers but, surprisingly, length of immobilisation was a protective factor. Survival analysis of pressure ulcer allows for identification of risk factors associated with this health problem in the intensive care units. Identifying these factors can help nurses establish interventions to prevent pressure ulcers in this healthcare scenario, given that pressure ulcers prevention is an indicator of nursing quality. © 2017 John Wiley & Sons Ltd.

Correlates of Bacterial Ulcers and Acute HSV-2 Infection among Men with Genital Ulcer Disease in South Africa: Age, Recent Sexual Behaviors, and HIV

OpenAIRE

Leichliter, Jami S.; Lewis, David A.; Paz-Bailey, Gabriela

2016-01-01

Data from baseline surveys and STI/HIV laboratory tests (n=615 men) were used to examine correlates of bacterial ulcers (Treponema pallidum, Haemophilus ducreyi, or Chlamydia trachomatis L1–L3 detected in ulcer) and acute HSV-2 ulcers (HSV-2 positive ulcer specimen, HSV-2 sero-negative, and negative for bacterial pathogens) vs. recurrent HSV-2 ulcers (sero-positive), separately. Compared to men with recurrent HSV-2 ulcers, men with bacterial ulcers had larger ulcers but were less likely to be...

Management strategies, early results, benefits, and risk factors of laparoscopic repair of perforated peptic ulcer.

Science.gov (United States)

Lunevicius, Raimundas; Morkevicius, Matas

2005-10-01

The primary goal of this study was to describe epidemiology and management strategies of the perforated duodenal ulcer, as well as the most common methods of laparoscopic perforated duodenal ulcer repair. The secondary goal was to demonstrate the value of prospective and retrospective studies regarding the early results of surgery and the risk factors. The tertiary goal was to emphasize the benefits of this operation, and the fourth goal was to clarify the possible risk factors associated with laparoscopic repair of the duodenal ulcer. The Medline/Pubmed database was used. Review was done after evaluation of 96 retrieved full-text articles. Thirteen prospective and twelve retrospective studies were selected, grouped, and summarized. The spectrum of the retrospective studies' results are as follows: median overall morbidity rate 10.5 %, median conversion rate 7%, median hospital stay 7 days, and median postoperative mortality rate 0%. The following is the spectrum of results of the prospective studies: median overall morbidity rate was slightly less (6%); the median conversion rate was higher (15%); the median hospital stay was shorter (5 days) and the postoperative mortality was higher (3%). The risk factors identified were the same. Shock, delayed presentation (> 24 hours), confounding medical condition, age > 70 years, poor laparoscopic expertise, ASA III-IV, and Boey score should be considered preoperative laparoscopic repair risk factors. Each of these factors independently should qualify as a criterion for open repair due to higher intraoperative risks as well as postoperative morbidity. Inadequate ulcer localization, large perforation size (defined by some as > 6 mm diameter, and by others as > 10 mm), and ulcers with friable edges are also considered as conversion risk factors.

[Epidemiological changes in peptic ulcer and their relation with Helicobacter pylori. Hospital Daniel A Carrion 2000-2005].

Science.gov (United States)

Montes Teves, Pedro; Salazar Ventura, Sonia; Monge Salgado, Eduardo

2007-01-01

Peptic ulcer disease is a frequent pathological condition. In the last few years there have been reports describing changes in its epidemiology and its association with Helicobacter pylori infection. To describe epidemiological characteristics of peptic ulcers during the study period from January 2000 through December 2005 in Hospital Daniel Carrion. Cross sectional analitical study. All patients with an endoscopic diagnosis of peptic ulcer were included. Patients with gastric cancer or previous surgery were excluded. Data were processed using the SPSS 9.0 software. We reviewed 10,819 endoscopy reports with 899 peptic ulcer cases diagnosed during the study period. 67.8% were male, age average 54 years. Age was higher in females (59.8 y), as was in those with gastric and pyloric ulcers (68.7 y). Most frequent endoscopic indications were upper gastrointestinal bleeding (53.3%) and dyspepsia (43.8%). Duodenal location was the most frequent (49.5%) although in recent years gastric ulcers have become more prevalent. Gastric ulcers were more commonly located in the antrum lesser curvature, while duodenal ulcers were located in the anterior wall of the duodenal bulb. Gastric ulcers were larger in size and more in number than duodenal ones. Helicobacter pylori was present in 65.3% of all ulcers, 74.3% for duodenal and 55.4% for gastric ulcers. Prevalence of peptic ulcers during the study period was 83.09 cases per 1,000 endoscopies. Duodenal ulcers were the most frequent although there is a decline in the last years. There is also a decrease in the frequency of Helicobacter pylori infection as compared to what is usually described.

PERFORATED PEPTIC ULCER: A CLINICAL ANALYSIS AND OUTCOME

OpenAIRE

Bijit

2016-01-01

BACKGROUND The incidence of perforated peptic ulcer is approximately 7-10 cases per one lakh population per year. Perforation is seen in about 7% of patients hospitalized for peptic ulcer disease. Peptic ulcer perforation, which can be gastric/duodenal perforation can be a serious life-threatening condition if not detected early and treated urgently. Peptic ulcer disease has decreased considerably worldwide with the advent of potent anti-ulcer medicines, but its complication l...

Hazard maps of Colima volcano, Mexico

Science.gov (United States)

Suarez-Plascencia, C.; Nunez-Cornu, F. J.; Escudero Ayala, C. R.

2011-12-01

Colima volcano, also known as Volcan de Fuego (19° 30.696 N, 103° 37.026 W), is located on the border between the states of Jalisco and Colima and is the most active volcano in Mexico. Began its current eruptive process in February 1991, in February 10, 1999 the biggest explosion since 1913 occurred at the summit dome. The activity during the 2001-2005 period was the most intense, but did not exceed VEI 3. The activity resulted in the formation of domes and their destruction after explosive events. The explosions originated eruptive columns, reaching attitudes between 4,500 and 9,000 m.a.s.l., further pyroclastic flows reaching distances up to 3.5 km from the crater. During the explosive events ash emissions were generated in all directions reaching distances up to 100 km, slightly affected nearby villages as Tuxpan, Tonila, Zapotlán, Cuauhtemoc, Comala, Zapotitlan de Vadillo and Toliman. During the 2005 this volcano has had an intense effusive-explosive activity, similar to the one that took place during the period of 1890 through 1900. Intense pre-plinian eruption in January 20, 1913, generated little economic losses in the lower parts of the volcano due to low population density and low socio-economic activities at the time. Shows the updating of the volcanic hazard maps published in 2001, where we identify whit SPOT satellite imagery and Google Earth, change in the land use on the slope of volcano, the expansion of the agricultural frontier on the east and southeast sides of the Colima volcano, the population inhabiting the area is approximately 517,000 people, and growing at an annual rate of 4.77%, also the region that has shown an increased in the vulnerability for the development of economic activities, supported by the construction of highways, natural gas pipelines and electrical infrastructure that connect to the Port of Manzanillo to Guadalajara city. The update the hazard maps are: a) Exclusion areas and moderate hazard for explosive events

Peptic Ulcer Disease and Helicobacter pylori Infection in Different Siberian Ethnicities.

Science.gov (United States)

Tsukanov, Vladislav V; Kasparov, Edward V; Tonkikh, Julia L; Shtygasheva, Olga V; Butorin, Nikolay N; Amelchugova, Olga S; Vasyutin, Alexander V; Bronnikova, Elena P; Fassan, Matteo; Rugge, Massimo

2017-02-01

The high prevalence of Helicobacter pylori (H. pylori) infection in eastern Siberia is consistently established. In the same geographic area, however, fragmentary information is available on the epidemiology of the peptic ulcer disease (PUD). To assess the prevalence of H. pylori infection (including CagA status) and PUD in different eastern Siberian ethnicities. An endoscopy population of 3149 eastern Siberian dyspeptic patients was considered [1727 Europoids and 1422 Mongoloids (Evenks = 792; Khakases = 630)]. H. pylori status was assessed by urease test and/or serum anti-H. pylori IgG and/or histology. CagA status was serologically assessed (anti-CagA antibodies). All the Siberian ethnicities featured high rates of H. pylori infection (Europoids = 87.1%, Evenks = 88.6%, Khakases = 85.4%). Among the 1504 H. pylori-positive Europoids, the prevalence of CagA-positive status (68.7%) was significantly higher than that featured by the 1240 H. pylori-positive Mongoloid ethnicities (46.9%; p Peptic ulcer disease significantly prevailed among Europoids (prevalence among Europoid Evenks and Khakases: 8.9% and 8.3%, respectively; prevalence among Mongoloid Evenks and Khakases = 1.0% and 4.4%, respectively). eastern Siberian populations feature consistent high rates of H. pylori infection, but different prevalence of peptic ulcer disease. In particular, Europoids featured a prevalence of both CagA-positive status and peptic ulcer disease significantly higher than that of the Mongoloid ethnicities. These results suggest that both environmental factors (coexisting with the H. pylori infection) and host-related variables modulate the clinicopathological expression of the H. pylori -associated gastric diseases. © 2016 John Wiley & Sons Ltd.

Coping style and depression influence the healing of diabetic foot ulcers: observational and mechanistic evidence.

Science.gov (United States)

Vedhara, K; Miles, J N V; Wetherell, M A; Dawe, K; Searle, A; Tallon, D; Cullum, N; Day, A; Dayan, C; Drake, N; Price, P; Tarlton, J; Weinman, J; Campbell, R

2010-08-01

Experimental evidence suggests that the healing of diabetic foot ulcers is affected by psychosocial factors such as distress. We examined this proposal in a prospective study, in which we considered the role of psychological distress and coping style in the healing of diabetic foot ulcers over a 24 week period. We also explored the role of salivary cortisol and matrix metalloproteinases (MMPs) as potential mechanisms. For this prospective observational study we recruited 93 (68 men; mean age 60 years) patients with neuropathic or neuroischaemic diabetic foot ulcers from specialist podiatry clinics in secondary care. Clinical and demographic determinants of healing, psychological distress, coping, salivary cortisol and both MMP2 and MMP9 were assessed at baseline. Ulcers were assessed at baseline and at 6, 12 and 24 weeks post-baseline. The primary outcome was ulcer status at 24 weeks, i.e. healed vs not healed. After controlling for clinical and demographic determinants of healing, ulcer healing at 24 weeks was predicted by confrontation coping, but not by depression or anxiety. Patients with unhealed ulcers exhibited greater confrontation coping (model including depression: OR 0.809, 95% CI 0.704-0.929, p = 0.003; model including anxiety: OR 0.810, 95% CI 0.704-0.930, p = 0.003). However, change in ulcer size over the observation period was associated with depression only (p = 0.04, d = 0.31). Healed ulcers by 24 weeks were also associated with lower evening cortisol, higher precursor MMP2 and a greater cortisol awakening response. Confrontation coping and depression predict ulcer healing. Our preliminary enquiry into biological mechanisms suggests that cortisol and precursor MMP2 may underlie these relationships.

One hundred years of volcano monitoring in Hawaii

Science.gov (United States)

Kauahikaua, Jim; Poland, Mike

2012-01-01

In 2012 the Hawaiian Volcano Observatory (HVO), the oldest of five volcano observatories in the United States, is commemorating the 100th anniversary of its founding. HVO's location, on the rim of Kilauea volcano (Figure 1)—one of the most active volcanoes on Earth—has provided an unprecedented opportunity over the past century to study processes associated with active volcanism and develop methods for hazards assessment and mitigation. The scientifically and societally important results that have come from 100 years of HVO's existence are the realization of one man's vision of the best way to protect humanity from natural disasters. That vision was a response to an unusually destructive decade that began the twentieth century, a decade that saw almost 200,000 people killed by the effects of earthquakes and volcanic eruptions.

Comparison of authigenic carbonates formation at mud volcanoes and pockmarks in the Portuguese Margin vs. at the Yinazao serpentinite mud volcano in the Marianas forearc

Science.gov (United States)

Magalhaes, V. H.; Freitas, M.; Azevedo, M. R.; Pinheiro, L. M.; Salgueiro, E.; Abrantes, F. F. G.

2017-12-01

On the Portuguese passive continental margin, active and past seepage processes form mud volcanoes and pockmarks at the seafloor. Often associated with these structures are extensive methane-derived authigenic carbonates that form from deep-sourced methane-rich fluids that ascend from deep to the upper sedimentary column and often discharge at the seafloor. These carbonates form within the sediments and are either dominated by dolomite and high-Mg calcites, when formed under a restricted seawater circulation environment, anoxic and low sulphate conditions; or by aragonite and calcite when formed close to or at the seafloor in a high sulphate system. The δ13C values (-56.2‰ VPDB) found on the carbonate-cemented material clearly indicates methane as the major carbon source. On the Yinazao serpentinite mud volcano at an active, non-accretionary, convergent margin, sediment samples from IODP Sites U1491 and U1492 (Exp. 366) contain authigenic minerals such as aragonite, calcite, brucite, gypsum among others. Authigenic aragonite occurs predominantly within the top meters of the cores where both oxidation and seawater circulation in the sedimentary column are higher. In this system, initial results indicate that the major carbon source is most probably not methane but seawater related. This work discusses and compares the major carbon sources in both systems: sedimentary mud volcanoes and pockmarks of a passive margin vs. a serpentinite mud volcano of an active, non-accretionary, convergent margin. We acknowledge the support from the PES project - Pockmarks and fluid seepage in the Estremadura Spur: implications for regional geology, biology, and petroleum systems (PTDC/GEOFIQ/5162/2014) financed by the Portuguese Foundation for Science and Technology (FCT).

Pressure ulcer development in trauma patients with suspected spinal injury; the influence of risk factors present in the Emergency Department.

Science.gov (United States)

Ham, H W Wietske; Schoonhoven, L Lisette; Schuurmans, M Marieke J; Leenen, L Luke P H

2017-01-01

To explore the influence of risk factors present at Emergency Department admission on pressure ulcer development in trauma patients with suspected spinal injury, admitted to the hospital for evaluation and treatment of acute traumatic injuries. Prospective cohort study setting level one trauma center in the Netherlands participants adult trauma patients transported to the Emergency Department on a backboard, with extrication collar and headblocks and admitted to the hospital for treatment or evaluation of their injuries. Between January and December 2013, 254 trauma patients were included. The following dependent variables were collected: Age, Skin color and Body Mass Index, and Time in Emergency Department, Injury Severity Score, Mean Arterial Pressure, hemoglobin level, Glasgow Coma Score, and admission ward after Emergency Department. Pressure ulcer development during admission was associated with a higher age (p 0.00, OR 1.05) and a lower Glasgow Coma Scale score (p 0.00, OR 1.21) and higher Injury Severity Scores (p 0.03, OR 1.05). Extra nutrition decreases the probability of PU development during admission (p 0.04, OR 0.20). Pressure ulcer development within the first 48h of admission was positively associated with a higher age (p 0.01, OR 1.03) and a lower Glasgow Coma Scale score (p 0.01, OR 1.16). The proportion of patients admitted to the Intensive Care Unit and Medium Care Unit was higher in patients with pressure ulcers. The pressure ulcer risk during admission is high in patients with an increased age, lower Glasgow Coma Scale and higher Injury Severity Score in the Emergency Department. Pressure ulcer risk should be assessed in the Emergency Department to apply preventive interventions in time. Copyright © 2016 Elsevier Ltd. All rights reserved.

Neonatal Pressure Ulcer Prevention.

Science.gov (United States)

Scheans, Patricia

2015-01-01

The incidence of pressure ulcers in acutely ill infants and children ranges up to 27 percent in intensive care units, with a range of 16-19 percent in NICUs. Anatomic, physiologic, and developmental factors place ill and preterm newborns at risk for skin breakdown. Two case studies illustrate these factors, and best practices for pressure ulcer prevention are described.

Volcanoes in the Classroom--an Explosive Learning Experience.

Science.gov (United States)

Thompson, Susan A.; Thompson, Keith S.

1996-01-01

Presents a unit on volcanoes for third- and fourth-grade students. Includes demonstrations; video presentations; building a volcano model; and inviting a scientist, preferably a vulcanologist, to share his or her expertise with students. (JRH)

[Weight loss and healing of ulcers - case report].

Science.gov (United States)

Seremet, Jasmina; Laginja, Stanislava; Marinović, Marin

2013-10-01

Diabetes mellitus type 2 is one of the most common diseases with a prevalence increasing with age. If blood sugar is not controlled, complications arise and diabetic foot ulcer occurs. Depending on the blood vessels involved, we distinguish venous and arterial ulcers. Venous ulcers respond very well to modern methods of treatment such as compression therapy and hydrocolloid dressings, but for arterial ulcer prevention is most significant, e.g. weight loss, dietary modification, etc. The aim of this study was to show that despite all the available therapeutic options, we cannot cure ulcers completely because the patient's readiness to change his lifestyle plays a decisive role. Therefore, we present a patient having suffered from venous ulcers for several years and arterial ulcer that healed only after the patient had lost about 20 pounds.

A mutein of human basic fibroblast growth factor TGP-580 accelerates colonic ulcer healing by stimulating angiogenesis in the ulcer bed in rats.

Science.gov (United States)

Satoh, H; Szabo, S

2015-10-01

Previously, we reported that TGP-580, a mutein of human basic fibroblast growth factor (bFGF), accelerated the healing of gastric and duodenal ulcers in rats. In the present study, we examined the effect of TGP-580 on the healing of colonic ulcers. In male Sprague Dawley rats, ulcers were induced in the colon 6 cm from the anus by enema of 50 μl of 3% N-ethylmaleimide, a sulfhydryl alkylator. The lesions were examined under a dissecting microscope (x10). The concentration of bFGF in the ulcerated colon was measured by enzyme immunoassay, and both the distribution of bFGF and the density of microvessels in the ulcer bed were examined by immunohistochemical staining. The content of bFGF in the ulcerated colon was markedly increased associated with ulcer healing, and ulcer healing was significantly delayed by intravenous administration of a monoclonal antibody for bFGF (MAb 3H3) once daily for 10 days. In the ulcer bed, many cells such as fibroblasts, vascular endothelial cells and macrophages were positively stained with bFGF antiserum. TGP-580, human bFGF or dexamethasone was given intracolonally twice daily for 10 days, starting the day after ulcer induction. TGP-580 (0.2 - 20 μg/ml, 200 μl/rat) dose-dependently accelerated ulcer healing, and its effect was more than 10 times stronger than that of human bFGF. Density (μm/0.01 mm(2)) of microvessels in the ulcer bed was significantly increased by treatment with TGP-580, and there was a good correlation between the density of microvessels and the decrease of ulcerated area (R(2) = 0.633). On the other hand dexamethasone (20 μg/ml) inhibited angiogenesis in the ulcer bed and delayed ulcer healing. These results suggest that angiogenesis in the ulcer bed plays an important role in ulcer healing, and that bFGF mutein TGP-580 accelerated colonic ulcer healing, at least in part, by stimulating angiogenesis, whereas glucocorticoids may delay the healing by inhibiting angiogenesis.

Clinical and cost-effectiveness of compression hosiery versus compression bandages in treatment of venous leg ulcers (Venous leg Ulcer Study IV, VenUS IV): a randomised controlled trial.

Science.gov (United States)

Ashby, Rebecca L; Gabe, Rhian; Ali, Shehzad; Adderley, Una; Bland, J Martin; Cullum, Nicky A; Dumville, Jo C; Iglesias, Cynthia P; Kang'ombe, Arthur R; Soares, Marta O; Stubbs, Nikki C; Torgerson, David J

2014-03-08

�0% bandage; p=0·02). 300 participants had 895 adverse events, of which 85 (9·5%) were classed as serious but unrelated to trial treatment. Two-layer compression hosiery is a viable alternative to the four-layer bandage-it is equally as effective at healing venous leg ulcers. However, a higher rate of treatment changes in participants in the hosiery group than in the bandage group suggests that hosiery might not be suitable for all patients. NIHR Health Technology Assessment programme (07/60/26). Copyright © 2014 Elsevier Ltd. All rights reserved.

Correlation between blood glucose levels and salivary glucose levels with oral ulcer in diabetic patients

Directory of Open Access Journals (Sweden)

Fildzah Rahman

2016-06-01

Full Text Available Diabetes Mellitus (DM is a syndrome in metabolism of carbohydrates which indicated by the increased level of blood glucose and also may increase salivary glucose levels. Oral ulcer has been frequently recognized in diabetic patients, which can be due to increased glucose in oral fluids and immune dysfunction. This study aimed to determine the correlation of blood glucose levels and salivary glucose levels with oral ulcer in diabetic patients. Analytic observational study was carried out through the determination of blood glucose levels just by way of strip using a glucometer and salivary glucose levels with the method "GOD-PAP test enzymatic colorimetric". Oral ulcer was determined in presenting ulcer on 30 patients with DM. The results showed r = 0.228, which is higher salivary glucose levels followed by high levels of blood glucose, and intraoral examination of oral ulcer found in the whole sample and the most location commonly found in buccal mucosa and lingual. It was concluded that there is a correlation between blood glucose levels and salivary glucose levels, and glucose levels affect the occurrence of oral ulcer in patients with DM

Standardisation of the USGS Volcano Alert Level System (VALS): analysis and ramifications

Science.gov (United States)

Fearnley, C. J.; McGuire, W. J.; Davies, G.; Twigg, J.

2012-11-01

The standardisation of volcano early warning systems (VEWS) and volcano alert level systems (VALS) is becoming increasingly common at both the national and international level, most notably following UN endorsement of the development of globally comprehensive early warning systems. Yet, the impact on its effectiveness, of standardising an early warning system (EWS), in particular for volcanic hazards, remains largely unknown and little studied. This paper examines this and related issues through evaluation of the emergence and implementation, in 2006, of a standardised United States Geological Survey (USGS) VALS. Under this upper-management directive, all locally developed alert level systems or practices at individual volcano observatories were replaced with a common standard. Research conducted at five USGS-managed volcano observatories in Alaska, Cascades, Hawaii, Long Valley and Yellowstone explores the benefits and limitations this standardisation has brought to each observatory. The study concludes (1) that the process of standardisation was predominantly triggered and shaped by social, political, and economic factors, rather than in response to scientific needs specific to each volcanic region; and (2) that standardisation is difficult to implement for three main reasons: first, the diversity and uncertain nature of volcanic hazards at different temporal and spatial scales require specific VEWS to be developed to address this and to accommodate associated stakeholder needs. Second, the plural social contexts within which each VALS is embedded present challenges in relation to its applicability and responsiveness to local knowledge and context. Third, the contingencies of local institutional dynamics may hamper the ability of a standardised VALS to effectively communicate a warning. Notwithstanding these caveats, the concept of VALS standardisation clearly has continuing support. As a consequence, rather than advocating further commonality of a standardised

Decreasing Magmatic Footprints of Individual Volcanos in a Waning Basaltic Field

Energy Technology Data Exchange (ETDEWEB)

G.A> Valentine; F.V. Perry

2006-06-06

The distribution and characteristics of individual basaltic volcanoes in the waning Southwestern Nevada Volcanic Field provide insight into the changing physical nature of magmatism and the controls on volcano location. During Pliocene-Pleistocene times the volumes of individual volcanoes have decreased by more than one order of magnitude, as have fissure lengths and inferred lava effusion rates. Eruptions evolved from Hawaiian-style eruptions with extensive lavas to eruptions characterized by small pulses of lava and Strombolian to violent Strombolian mechanisms. These trends indicate progressively decreasing partial melting and length scales, or magmatic footprints, of mantle source zones for individual volcanoes. The location of each volcano is determined by the location of its magmatic footprint at depth, and only by shallow structural and topographic features that are within that footprint. The locations of future volcanoes in a waning system are less likely to be determined by large-scale topography or structures than were older, larger volume volcanoes.

Medical management of venous ulcers.

Science.gov (United States)

Pascarella, Luigi; Shortell, Cynthia K

2015-03-01

Venous disease is the most common cause of chronic leg ulceration and represents an advanced clinical manifestation of venous insufficiency. Due to their frequency and chronicity, venous ulcers have a high socioeconomic impact, with treatment costs accounting for 1% of the health care budget in Western countries. The evaluation of patients with venous ulcers should include a thorough medical history for prior deep venous thrombosis, assessment for an hypercoagulable state, and a physical examination. Use of the CEAP (clinical, etiology, anatomy, pathophysiology) Classification System and the revised Venous Clinical Severity Scoring System is strongly recommended to characterize disease severity and assess response to treatment. This venous condition requires lifestyle modification, with affected individuals performing daily intervals of leg elevation to control edema; use of elastic compression garments; and moderate physical activity, such as walking wearing below-knee elastic stockings. Meticulous skin care, treatment of dermatitis, and prompt treatment of cellulitis are important aspects of medical management. The pharmacology of chronic venous insufficiency and venous ulcers include essentially two medications: pentoxifylline and phlebotropic agents. The micronized purified flavonoid fraction is an effective adjunct to compression therapy in patients with large, chronic ulceration. Copyright © 2015 Elsevier Inc. All rights reserved.

Longitudinal study of influence of Helicobacter pylori on current risk of duodenal ulcer relapse. The Hvidovre Ulcer Project Group

DEFF Research Database (Denmark)

Clausen, M R; Franzmann, M B; Holst, C

1992-01-01

acid output, time of healing of the preceding ulcer, treatment of the present ulcer (cimetidine, antacids, or no treatment), or type and degree of gastritis. Thus, although H. pylori is prevalent in patients with duodenal ulcer disease, the present study indicates that H. pylori does not have.......052-0.133), 0.123 (0.096-0.157), and 0.069 (0.041-0.116), respectively. No significant differences in incidence rates across H. pylori scores were observed when taking into account the observation period after healing of the first ulcer, number of ulcer recurrence (1st, 2nd, 3rd), sex, age, smoking habits, peak...

Cellular immune responses and phagocytic activity of fishes exposed to pollution of volcano mud.

Science.gov (United States)

Risjani, Yenny; Yunianta; Couteau, Jerome; Minier, Christophe

2014-05-01

Since May 29, 2006, a mud volcano in the Brantas Delta of the Sidoarjo district has emitted mud that has inundated nearby villages. Pollution in this area has been implicated in detrimental effects on fish health. In fishes, leukocyte and phagocytic cells play a vital role in body defenses. We report for the first time the effect of "LUSI" volcano mud on the immune systems of fish in the Brantas Delta. The aim of this study was to find biomarkers to allow the evaluation of the effects of volcanic mud and anthropogenic pollution on fish health in the Brantas Delta. The study took places at the Brantas Delta, which was polluted by volcano mud, and at reference sites in Karangkates and Pasuruan. Leukocyte numbers were determined using a Neubauer hemocytometer and a light microscope. Differential leukocyte counts were determined using blood smears stained with May Grunwald-Giemsa, providing neutrophil, lymphocyte and monocyte counts. Macrophages were taken from fish kidney, and their phagocytic activity was measured. In vitro analyses revealed that leukocyte and differential leukocyte counts (DLC) were higher in Channa striata and Chanos chanos caught from the polluted area. Macrophage numbers were higher in Oreochromis mossambicus than in the other species, indicating that this species is more sensitive to pollution. In areas close to volcanic mud eruption, all specimens had lower phagocytic activity. Our results show that immune cells were changed and phagocytic activity was reduced in the polluted area indicating cytotoxicity and alteration of the innate immune system in fishes exposed to LUSI volcano mud and anthropogenic pollution. Copyright © 2014 Elsevier Ltd. All rights reserved.

Helicobacter pylori : the causative agent of peptic ulcer ...

African Journals Online (AJOL)

This review examines Helicobacter pylori as an organism and as the causative agent of peptic ulcers. The review also examined the classification of ulcers, ... Elimination of Helicobacter pylori by treatment with antibiotics in peptic ulcer patients resulted in the healing of the ulcer. Prevention of Helicobacter pylori infections is ...

Diabetic foot ulcers. Pathophysiology, assessment, and therapy.

OpenAIRE

Bowering, C. K.

2001-01-01

OBJECTIVE: To review underlying causes of diabetic foot ulceration, provide a practical assessment of patients at risk, and outline an evidence-based approach to therapy for diabetic patients with foot ulcers. QUALITY OF EVIDENCE: A MEDLINE search was conducted for the period from 1979 to 1999 for articles relating to diabetic foot ulcers. Most studies found were case series or small controlled trials. MAIN MESSAGE: Foot ulcers in diabetic patients are common and frequently lead to lower limb...

Establishment, test and evaluation of a prototype volcano surveillance system

Science.gov (United States)

Ward, P. L.; Eaton, J. P.; Endo, E.; Harlow, D.; Marquez, D.; Allen, R.

1973-01-01

A volcano-surveillance system utilizing 23 multilevel earthquake counters and 6 biaxial borehole tiltmeters is being installed and tested on 15 volcanoes in 4 States and 4 foreign countries. The purpose of this system is to give early warning when apparently dormant volcanoes are becoming active. The data are relayed through the ERTS-Data Collection System to Menlo Park for analysis. Installation was completed in 1972 on the volcanoes St. Augustine and Iliamna in Alaska, Kilauea in Hawaii, Baker, Rainier and St. Helens in Washington, Lassen in California, and at a site near Reykjavik, Iceland. Installation continues and should be completed in April 1973 on the volcanoes Santiaguito, Fuego, Agua and Pacaya in Guatemala, Izalco in El Salvador and San Cristobal, Telica and Cerro Negro in Nicaragua.

Evaluation of landslide susceptibility of Sete Cidades Volcano (S. Miguel Island, Azores

Directory of Open Access Journals (Sweden)

A. Gomes

2005-01-01

Full Text Available Sete Cidades is an active central volcano with a summit caldera located in the westernmost part of S. Miguel Island (Azores. Since the settlement of the Island, in the 15th century, many landslide events occurred in this volcano, causing extensive damages in buildings and infrastructures. The study of historical records and the observation of new occurrences showed that landslides in the region have been triggered by heavy rainfall periods, earthquakes and erosion. In order to assess landslide susceptibility at Sete Cidades Volcano, landslide scars and associated deposits were mapped through aerial photographs and field surveys. The obtained data were inserted in a GIS to produce a landslide distribution map. It was concluded that the high density landslide areas are related with (1 major scarp faults, (2 the margin of fluvial channels, (3 the sea cliffs and (4 volcanic landforms, namely the caldera wall. About 73% of the mapped events took place in areas where pyroclastic deposits are the dominant lithology and more than 77% occurred where slopes are equal or higher than 20°. These two parameters were integrated and used to generate a preliminary susceptibility map. The incorporation of vulnerability data into the GIS allowed concluding that 30% of dwellings and most of the roads on Sete Cidades Volcano are located in areas where landslide susceptibility is high to very high. Such conclusion should be taken into account for emergency and land use planning.

Mucosal injury and γ-irradiation produce persistent gastric ulcers in the rabbit. Evaluation of antiulcer drug binding to experimental ulcer sites

International Nuclear Information System (INIS)

Yokel, R.A.; Dickey, K.M.

1991-01-01

A method producing persistent gastric ulcers in the rhesus monkey by combined mucosal injury and γ-irradiation was modified and evaluated in the rabbit. γ-Irradiation (800-1000 cGy) immediately after removal of 2-mm-diameter sections of antral mucosa resulted in ulcer craters 5-7 days later. Ulcer sites were characterized by loss of the mucosa, muscularis mucosa, and much of the submucosa. The exposed submucosa was coated with fibrin and necrotic debris infiltrated with heterophils, the rabbit equivalent of neutrophils. These ulcers strongly resemble human chronic gastric ulcers. Binding of Carafate (sucralfate; Marion Laboratories, Inc., Kansas City, MO) and Maalox (magnesia-alumina oral suspension; Wm. H. Rorer, Inc., Ft. Washington, PA) to ulcer and nearby nonulcer sites in the antrum was assessed 1 hour after drug dosing. Drug binding was determined by aluminum quantitation of stomach wall punch biopsies at necropsy. Both drugs significantly increased aluminum bound to the stomach wall compared with vehicle treatment. Significantly more antiulcer drug was bound to ulcer sites than to nearby nonulcer sites only after sucralfate administration. This model of persistent gastric ulcer should be useful to further study gastric ulcer pathogenesis and treatment

Current management of peptic ulcer perforations

International Nuclear Information System (INIS)

Menakuru, S.R.

2004-01-01

Perforation is a life-threatening complication of peptic ulcer disease. Smoking and use of non-steroidal anti-inflammatory drugs are important risk factors for perforation. Diagnosis is made clinically and confirmed by the presence of pneumoperitoneum on radiographs. Nonoperative management is successful in patients identified to have a spontaneously sealed perforation proven by water-soluble contrast gastroduodenogram. Operative management consists of the time-honoured practice of mental patch closure, but now this can be done by laparoscopic methods. The practice of addition of acid-reducing procedures is currently being debated though it continues to be recommended in good-risk patients. Laparoscopic approaches to closure of duodenal perforation are now being applied widely and may become the gold standard in the future especially in patients with < 10 mm perforation size presenting within the first 24 hours of onset of pain. The role of Helicobacter pylori in duodenal ulcer perforation is controversial and more studies are needed to answer this question though recent indirect evidence suggests that eradicating H pylori may reduce the necessity for adding acid reducing procedures and the associated morbidity. Perforation is a life-threatening complication of peptic ulcer disease. The management of peptic ulcer disease has evolved over the decades, due to advances in operative techniques, bacteriology and pharmacology. While the recognition of the role of Helicobacter pylori (H. pylori) in peptic ulceration has resulted in a paradigm shift in the management of uncomplicated peptic ulcers, debate continues about the appropriate management of perforated duodenal bulb and prepyloric ulcers. A new dimension has been added to this controversy by the advent of laparoscopic techniques for closing the perforation. A Medline search of all articles dealing with the management of peptic ulcer perforation published after 1985 was undertaken. The short listed articles were

Prognostic stratification of ulcerated melanoma

DEFF Research Database (Denmark)

Bønnelykke-Behrndtz, Marie L; Schmidt, Henrik; Christensen, Ib J

2014-01-01

OBJECTIVES: For patients with melanoma, ulceration is an important prognostic marker and interestingly also a predictive marker for the response of adjuvant interferon. A consensual definition and accurate assessment of ulceration are therefore crucial for proper staging and clinical management. We...

Topical phenytoin for treating pressure ulcers.

Science.gov (United States)

Hao, Xiang Yong; Li, Hong Ling; Su, He; Cai, Hui; Guo, Tian Kang; Liu, Ruifeng; Jiang, Lei; Shen, Yan Fei

2017-02-22

Pressure ulcers are common in clinical practice and pose a significant health problem worldwide. Apart from causing suffering to patients, they also result in longer hospital stays and increase the cost of health care. A variety of methods are used for treating pressure ulcers, including pressure relief, patient repositioning, biophysical strategies, nutritional supplementation, debridement, topical negative pressure, and local treatments including dressings, ointments and creams such as bacitracin, silver sulphadiazine, neomycin, and phenytoin. Phenytoin is a drug more commonly used in the treatment of epilepsy, but may play an important role in accelerating ulcer healing. To assess the effects of topical phenytoin on the rate of healing of pressure ulcers of any grade, in any care setting. In September 2016, we searched the following electronic databases to identify relevant randomized clinical trials: the Cochrane Wounds Specialised Register; the Cochrane Central Register of Controlled Trials (CENTRAL; the Cochrane Library); Ovid MEDLINE; Ovid Embase; and EBSCO CINAHL Plus. We handsearched conference proceedings from the European Pressure Ulcer Advisory Panel, European Wound Management Association and the Tissue Viability Society for all available years. We searched the references of the retrieved trials to identify further relevant trials. We also searched clinical trials registries to identify ongoing and unpublished studies. There were no restrictions with respect to language, date of publication or study setting. We included all randomized controlled trials (RCTs) addressing the effects (both benefits and harms) of topical phenytoin on the healing of pressure ulcers of any grade compared with placebo or alternative treatments or no therapy, irrespective of blinding, language, and publication status. Two review authors independently selected studies, extracted information on participants, interventions, methods and results and assessed risk of bias using

Understanding cyclic seismicity and ground deformation patterns at volcanoes: Intriguing lessons from Tungurahua volcano, Ecuador

Science.gov (United States)

Neuberg, Jürgen W.; Collinson, Amy S. D.; Mothes, Patricia A.; Ruiz, Mario C.; Aguaiza, Santiago

2018-01-01

Cyclic seismicity and ground deformation patterns are observed on many volcanoes worldwide where seismic swarms and the tilt of the volcanic flanks provide sensitive tools to assess the state of volcanic activity. Ground deformation at active volcanoes is often interpreted as pressure changes in a magmatic reservoir, and tilt is simply translated accordingly into inflation and deflation of such a reservoir. Tilt data recorded by an instrument in the summit area of Tungurahua volcano in Ecuador, however, show an intriguing and unexpected behaviour on several occasions: prior to a Vulcanian explosion when a pressurisation of the system would be expected, the tilt signal declines significantly, hence indicating depressurisation. At the same time, seismicity increases drastically. Envisaging that such a pattern could carry the potential to forecast Vulcanian explosions on Tungurahua, we use numerical modelling and reproduce the observed tilt patterns in both space and time. We demonstrate that the tilt signal can be more easily explained as caused by shear stress due to viscous flow resistance, rather than by pressurisation of the magmatic plumbing system. In general, our numerical models prove that if magma shear viscosity and ascent rate are high enough, the resulting shear stress is sufficient to generate a tilt signal as observed on Tungurahua. Furthermore, we address the interdependence of tilt and seismicity through shear stress partitioning and suggest that a joint interpretation of tilt and seismicity can shed new light on the eruption potential of silicic volcanoes.

Pathophysiology diabetic foot ulcer

Science.gov (United States)

Syafril, S.

2018-03-01

Diabetes Mellitus (DM) is known to have many complications. Diabetes and its complications are rapidly becoming the world’s most significant cause of morbidity and mortality, and one of the most distressing is Diabetic Foot Ulcer (DFU). Chronic wound complications are a growing concern worldwide, and the effect is a warning to public health and the economy. The etiology of a DFU is multifaceted, and several components cause added together create a sufficient impact on ulceration: neuropathy, vasculopathy, immunopathy, mechanical stress, and neuroarthropathy. There are many classifications of the diabetic foot. About 50% of patients with foot ulcers due to DM present clinical signs of infection. It is essential to manage multifactorial etiology of DFU to get a good outcome.

Roentgenologic image of penetrating duodenal bulb ulcer

International Nuclear Information System (INIS)

Strunin, A.E.

1986-01-01

When studying a series of aimed roentgenograms in patients with peptic ulcer a gas bubble of irregular spherical configuration or two-layer niche were determined near the bulb medial contour. Gas bubble was from 0.5-0.7 to 3.5 cm in diameter. In such cases penetrating ulcers were determined in operations. Along with other signs gas bubble symptom, sometimes two-layer signs may be used for timely and exact roentgenological diagnosis of penetrating duodenal bulb ulcer in peptic ulcer disease

Catalogue of Icelandic Volcanoes

Science.gov (United States)

Ilyinskaya, Evgenia; Larsen, Gudrún; Gudmundsson, Magnús T.; Vogfjörd, Kristin; Jonsson, Trausti; Oddsson, Björn; Reynisson, Vidir; Pagneux, Emmanuel; Barsotti, Sara; Karlsdóttir, Sigrún; Bergsveinsson, Sölvi; Oddsdóttir, Thorarna

2017-04-01

The Catalogue of Icelandic Volcanoes (CIV) is a newly developed open-access web resource (http://icelandicvolcanoes.is) intended to serve as an official source of information about volcanoes in Iceland for the public and decision makers. CIV contains text and graphic information on all 32 active volcanic systems in Iceland, as well as real-time data from monitoring systems in a format that enables non-specialists to understand the volcanic activity status. The CIV data portal contains scientific data on all eruptions since Eyjafjallajökull 2010 and is an unprecedented endeavour in making volcanological data open and easy to access. CIV forms a part of an integrated volcanic risk assessment project in Iceland GOSVÁ (commenced in 2012), as well as being part of the European Union funded effort FUTUREVOLC (2012-2016) on establishing an Icelandic volcano supersite. The supersite concept implies integration of space and ground based observations for improved monitoring and evaluation of volcanic hazards, and open data policy. This work is a collaboration of the Icelandic Meteorological Office, the Institute of Earth Sciences at the University of Iceland, and the Civil Protection Department of the National Commissioner of the Iceland Police, with contributions from a large number of specialists in Iceland and elsewhere.

Prevalence of pressure ulcer and associated risk factors in middle- and older-aged medical inpatients in Norway.

Science.gov (United States)

Børsting, Tove E; Tvedt, Christine R; Skogestad, Ingrid J; Granheim, Tove I; Gay, Caryl L; Lerdal, Anners

2018-02-01

To describe the prevalence of pressure ulcers among middle- and older-aged patients in a general medical hospital in Norway and to describe the associations between pressure ulcers and potential risk factors additional to the Braden risk score. Degrees of mobility, activity, perfusion and skin status are risk factors for development of pressure ulcer. Nurses' clinical judgements combined with risk assessment tools are effective to detect pressure ulcer risk. Cross-sectional study. The study was performed as part of a research project conducted between September 2012-May 2014 in a general hospital in the capital of Norway. Registered nurses and nursing students collected data from all eligible patients on 10 days during the students' clinical practice studies. The Braden scale was used to measure pressure ulcer risk, and skin examinations were performed to classify the skin area as normal or as indicative of pressure ulcer according to the definitions by the National Pressure Ulcer Advisory Panel. Comorbidities were collected by patient's self-report. This analysis focused on the 255 inpatients at the medical wards ≥52 years of age, most of whom had more than one comorbidity. The prevalence of pressure ulcers was 14.9% in this sample. Higher age, underweight, diabetes and worse Braden scores were factors associated with pressure ulcer, and pressure ulcer was most frequently sited at the sacrum or heel. Adding age, weight and diabetes status to pressure ulcer risk assessment scales may improve identification of patients at risk for pressure ulcers. Knowledge about strengths and limitations of risk assessment tools is important for clinical practice. Age, weight and diabetes status should be considered for inclusion in risk assessment tools for pressure ulcers in medical wards. © 2017 John Wiley & Sons Ltd.

Probiotics and prebiotics in ulcerative colitis.

Science.gov (United States)

Derikx, Lauranne A A P; Dieleman, Levinus A; Hoentjen, Frank

2016-02-01

The intestinal microbiota is one of the key players in the etiology of ulcerative colitis. Manipulation of this microflora with probiotics and prebiotics is an attractive strategy in the management of ulcerative colitis. Several intervention studies for both the induction and maintenance of remission in ulcerative colitis patients have been performed. Most of these studies evaluated VSL#3 or E. Coli Nissle 1917 and in general there is evidence for efficacy of these agents for induction and maintenance of remission. However, studies are frequently underpowered, lack a control group, and are very heterogeneous investigating different probiotic strains in different study populations. The absence of well-powered robust randomized placebo-controlled trials impedes the widespread use of probiotics and prebiotics in ulcerative colitis. However, given the promising results that are currently available, probiotics and prebiotics may find their way to the treatment algorithm for ulcerative colitis in the near future. Copyright © 2016 Elsevier Ltd. All rights reserved.

Pressure ulcer research : current and future perspectives

NARCIS (Netherlands)

Bader, D.L.; Bouten, C.V.C.; Colin, D.; Oomens, C.W.J.

2005-01-01

This book provides an up-to-date scientific account of all aspects related to pressure ulcers and pressure ulcer research, as well as evidence-based knowledge of pressure ulcer aetiology. Further, it describes current and future tools for evaluating patients at risk. It comprises 20 chapters by

Imaging magma plumbing beneath Askja volcano, Iceland

Science.gov (United States)

Greenfield, Tim; White, Robert S.

2015-04-01

and velocity structure. The 2014-15 Bárðarbunga dyke intrusion has provided a 45 km long, distributed source of large earthquakes which are well located and provide accurate arrival time picks. Together with long-term background seismicity these provide excellent illumination of the Askja volcano from all directions. We find a pronounced low-velocity anomaly beneath the caldera at a depth of ~7 km. The anomaly is ~10% slower than the initial best fitting 1D model and has a Vp/Vs ratio higher than the surrounding crust, suggesting the presence of increased temperature or partial melt. The body is unlikely to be entirely melt as S-waves are still detected at stations directly above the anomaly. This low-velocity body is slightly deeper than the depth range suggested by InSAR and GPS studies of a deflating source beneath Askja. Beneath the main low-velocity zone a region of reduced velocities extends into the lower crust and is coincident with deep seismicity. This is suggestive of a high temperature channel into the lower crust which could be a pathway for melt rising from the mantle.

Multiple Active Volcanoes in the Northeast Lau Basin

Science.gov (United States)

Baker, E. T.; Resing, J. A.; Lupton, J. E.; Walker, S. L.; Embley, R. W.; Rubin, K. H.; Buck, N.; de Ronde, C. E.; Arculus, R. J.

2010-12-01

The northeast Lau Basin occupies a complex geological area between the Tafua arc front, the E-W trending Tonga Trench, and the Northeast Lau Spreading Center. These boundaries create multiple zones of extension and thus provide abundant opportunities for magma to invade the crust. The 25-km-long chain of “Mata” volcanoes lies near the center of this area, separated from both the arc front and the spreading ridge. In 2008 we discovered hydrothermal venting on the largest and most southerly of these volcanoes, W and E Mata. In 2010 we visited the 7 smaller volcanoes that form a 15-km-long arcuate sweep to the north from W and E Mata (the “North Matas”). We also revisited W and E Mata. Over each volcano we conducted CTD tows to map plumes and collect water samples. Based on the CTD results, camera tows searched for seafloor sources on three volcanoes. The N Mata volcanoes, extending from Mata Taha (1) in the south to Mata Fitu (7) in the north, lie within a prominent gap in the shallow bathymetry along the southern border of the Tonga trench. Northward from E Mata the Mata volcanoes degrade from large symmetrical cones to smaller and blocky volcanic edifices. Summit depths range from 1165 m (W Mata) to 2670 m (Mata Nima (5)). The most active volcano in the chain is the erupting W Mata, with an intense plume that extended 250 m above the summit. Hydrothermal temperature anomalies (Δθ, corrected for hydrographic masking effects) reached ˜1.7°C, with light-scattering values as high as 2-5 ΔNTU. The 2010 surveys now show that 6 of the 7 N Mata volcanoes are also hydrothermally active. Along the N Matas, Δθ and ΔNTU signals ranged from robust to weak, but distinct oxidation-reduction potential (aka Eh) anomalies confirmed active venting in each case. The most concentrated plumes were found near Mata Ua (2) and Mata Fitu (7), with Δθ and ΔNTU maxima of 0.1-0.17°C and 0.3, respectively. Despite the variability in plume strength, however, ΔNTU/Δθ ratios

Actovegin administration in patients with ulcerated gout tophuses

Directory of Open Access Journals (Sweden)

M S Eliseev

2005-01-01

Full Text Available Objective. To study actovegin efficacy in the treatment of chronic skin ulcers due to ulceration of tophuses in pts with chronic tophaceous gout. Materials and methods. 6 pts with chronic tophaceous gout aged 52 to 77 years with disease duration from 6 to 20 years with longstanding persisting skin ulcers due to tophuses ulceration were included. In addition to allopuri- nol, steroid and nonsteroidal anti-inflammatory drugs they were treated with actovegin 20% intravenously and local applications of 2% actovegin gel. Clinical examination was performed before and after the course of therapy- Results. Two from six pts showed healing of single chronic ulcers to the end of the treatment course. In the remaining pts ulcer count and size decrease was achieved. Conclusion. Actovegin administration in combined therapy of chronic skin ulcers in pts with chronic tophaceous gout promoted healing of the defects in all cases.

The National Expert Standard Pressure Ulcer Prevention in Nursing and pressure ulcer prevalence in German health care facilities: a multilevel analysis.

Science.gov (United States)

Wilborn, Doris; Grittner, Ulrike; Dassen, Theo; Kottner, Jan

2010-12-01

The objective of this study was to describe the relationship between the German National Expert Standard Pressure Ulcer Prevention and the pressure ulcer prevalence in German nursing homes and hospitals. The patient outcome pressure ulcer does not only depend on individual characteristics of patients, but also on institutional factors. In Germany, National Expert Standards are evidence-based instruments that build the basis of continuing improvement in health care quality. It is expected that after having implemented the National Expert Standard Pressure Ulcer Prevention, the number of pressure ulcers should decrease in health care institutions. The analysed data were obtained from two cross-sectional studies from 2004-2005. A multilevel analysis was performed to show the impact of the National Expert Standard Pressure Ulcer Prevention on pressure ulcer prevalence. A total of 41.5% of hospitals and 38.8% of the nursing homes claimed to use the National Expert Standard in the process of developing their local protocols. The overall pressure ulcer prevalence grade 2-4 was 4.7%. Adjusted for hospital departments, survey year and individual characteristics, there was no significant difference in the prevalence of pressure ulcers between institutions that refer to the National Expert Standard or those referring to other sources in developing their local protocols (OR=1.14, 95% CI=0.90-1.44). There was no empirical evidence demonstrating that local protocols of pressure ulcer prevention based on the National Expert Standard were superior to local protocols which refer other sources of knowledge with regard to the pressure ulcer prevalence. The use of the National Expert Standard Pressure Ulcer Prevention can neither be recommended nor be refused. The recent definition of implementation of Expert Standards should be mandatory for all health care institutions which introduce Expert Standards. © 2010 Blackwell Publishing Ltd.

Effect of e-learning program on risk assessment and pressure ulcer classification - A randomized study.

Science.gov (United States)

Bredesen, Ida Marie; Bjøro, Karen; Gunningberg, Lena; Hofoss, Dag

2016-05-01

Pressure ulcers (PUs) are a problem in health care. Staff competency is paramount to PU prevention. Education is essential to increase skills in pressure ulcer classification and risk assessment. Currently, no pressure ulcer learning programs are available in Norwegian. Develop and test an e-learning program for assessment of pressure ulcer risk and pressure ulcer classification. Forty-four nurses working in acute care hospital wards or nursing homes participated and were assigned randomly into two groups: an e-learning program group (intervention) and a traditional classroom lecture group (control). Data was collected immediately before and after training, and again after three months. The study was conducted at one nursing home and two hospitals between May and December 2012. Accuracy of risk assessment (five patient cases) and pressure ulcer classification (40 photos [normal skin, pressure ulcer categories I-IV] split in two sets) were measured by comparing nurse evaluations in each of the two groups to a pre-established standard based on ratings by experts in pressure ulcer classification and risk assessment. Inter-rater reliability was measured by exact percent agreement and multi-rater Fleiss kappa. A Mann-Whitney U test was used for continuous sum score variables. An e-learning program did not improve Braden subscale scoring. For pressure ulcer classification, however, the intervention group scored significantly higher than the control group on several of the categories in post-test immediately after training. However, after three months there were no significant differences in classification skills between the groups. An e-learning program appears to have a greater effect on the accuracy of pressure ulcer classification than classroom teaching in the short term. For proficiency in Braden scoring, no significant effect of educational methods on learning results was detected. Copyright © 2016 Elsevier Ltd. All rights reserved.

Increased Mortality in Diabetic Foot Ulcer Patients: The Significance of Ulcer Type

Science.gov (United States)

Chammas, N. K.; Hill, R. L. R.; Edmonds, M. E.

2016-01-01

Diabetic foot ulcer (DFU) patients have a greater than twofold increase in mortality compared with nonulcerated diabetic patients. We investigated (a) cause of death in DFU patients, (b) age at death, and (c) relationship between cause of death and ulcer type. This was an eleven-year retrospective study on DFU patients who attended King's College Hospital Foot Clinic and subsequently died. A control group of nonulcerated diabetic patients was matched for age and type of diabetes mellitus. The cause of death was identified from death certificates (DC) and postmortem (PM) examinations. There were 243 DFU patient deaths during this period. Ischaemic heart disease (IHD) was the major cause of death in 62.5% on PM compared to 45.7% on DC. Mean age at death from IHD on PM was 5 years lower in DFU patients compared to controls (68.2 ± 8.7 years versus 73.1 ± 8.0 years, P = 0.015). IHD as a cause of death at PM was significantly linked to neuropathic foot ulcers (OR 3.064, 95% CI 1.003–9.366, and P = 0.049). Conclusions. IHD is the major cause of premature mortality in DFU patients with the neuropathic foot ulcer patients being at a greater risk. PMID:27213157

Pressure ulcer prevention program: a journey.

Science.gov (United States)

Delmore, Barbara; Lebovits, Sarah; Baldock, Philip; Suggs, Barbara; Ayello, Elizabeth A

2011-01-01

The Centers for Medicare & Medicaid Services' regulations regarding nonpayment for hospital-acquired conditions such as pressure ulcers have prompted a marked increase in focus on preventive care. Our hospital also used this change in payment policy as an opportunity to strengthen our pressure ulcer prevention practices. We used an 8-spoke prevention wheel to develop and implement practice changes that reduced pressure ulcer incidence from 7.3% to 1.3% in 3 years. Because it is about the journey, we will describe the mechanisms we designed and implemented, and identify strategies that worked or did not work as we promulgated a quality improvement process for pressure ulcer prevention in our large urban hospital center.

Copahue volcano and its regional magmatic setting

Science.gov (United States)

Varekamp, J C; Zareski, J E; Camfield, L M; Todd, Erin

2016-01-01

Copahue volcano (Province of Neuquen, Argentina) has produced lavas and strombolian deposits over several 100,000s of years, building a rounded volcano with a 3 km elevation. The products are mainly basaltic andesites, with the 2000–2012 eruptive products the most mafic. The geochemistry of Copahue products is compared with those of the main Andes arc (Llaima, Callaqui, Tolhuaca), the older Caviahue volcano directly east of Copahue, and the back arc volcanics of the Loncopue graben. The Caviahue rocks resemble the main Andes arc suite, whereas the Copahue rocks are characterized by lower Fe and Ti contents and higher incompatible element concentrations. The rocks have negative Nb-Ta anomalies, modest enrichments in radiogenic Sr and Pb isotope ratios and slightly depleted Nd isotope ratios. The combined trace element and isotopic data indicate that Copahue magmas formed in a relatively dry mantle environment, with melting of a subducted sediment residue. The back arc basalts show a wide variation in isotopic composition, have similar water contents as the Copahue magmas and show evidence for a subducted sedimentary component in their source regions. The low 206Pb/204Pb of some backarc lava flows suggests the presence of a second endmember with an EM1 flavor in its source. The overall magma genesis is explained within the context of a subducted slab with sediment that gradually looses water, water-mobile elements, and then switches to sediment melt extracts deeper down in the subduction zone. With the change in element extraction mechanism with depth comes a depletion and fractionation of the subducted complex that is reflected in the isotope and trace element signatures of the products from the main arc to Copahue to the back arc basalts.

Spying on volcanoes

Science.gov (United States)

Watson, Matthew

2017-07-01

Active volcanoes can be incredibly dangerous, especially to those who live nearby, but how do you get close enough to observe one in action? Matthew Watson explains how artificial drones are providing volcanologists with insights that could one day save human lives

Geologic Map of the Summit Region of Kilauea Volcano, Hawaii

Science.gov (United States)

Neal, Christina A.; Lockwood, John P.

2003-01-01

This report consists of a large map sheet and a pamphlet. The map shows the geology, some photographs, description of map units, and correlation of map units. The pamphlet gives the full text about the geologic map. The area covered by this map includes parts of four U.S. Geological Survey 7.5' topographic quadrangles (Kilauea Crater, Volcano, Ka`u Desert, and Makaopuhi). It encompasses the summit, upper rift zones, and Koa`e Fault System of Kilauea Volcano and a part of the adjacent, southeast flank of Mauna Loa Volcano. The map is dominated by products of eruptions from Kilauea Volcano, the southernmost of the five volcanoes on the Island of Hawai`i and one of the world's most active volcanoes. At its summit (1,243 m) is Kilauea Crater, a 3 km-by-5 km collapse caldera that formed, possibly over several centuries, between about 200 and 500 years ago. Radiating away from the summit caldera are two linear zones of intrusion and eruption, the east and the southwest rift zones. Repeated subaerial eruptions from the summit and rift zones have built a gently sloping, elongate shield volcano covering approximately 1,500 km2. Much of the volcano lies under water; the east rift zone extends 110 km from the summit to a depth of more than 5,000 m below sea level; whereas the southwest rift zone has a more limited submarine continuation. South of the summit caldera, mostly north-facing normal faults and open fractures of the Koa`e Fault System extend between the two rift zones. The Koa`e Fault System is interpreted as a tear-away structure that accommodates southward movement of Kilauea's flank in response to distension of the volcano perpendicular to the rift zones.

Longitudinal study of influence of Helicobacter pylori on current risk of duodenal ulcer relapse. The Hvidovre Ulcer Project Group

DEFF Research Database (Denmark)

Clausen, M R; Franzmann, M B; Holst, C

1992-01-01

acid output, time of healing of the preceding ulcer, treatment of the present ulcer (cimetidine, antacids, or no treatment), or type and degree of gastritis. Thus, although H. pylori is prevalent in patients with duodenal ulcer disease, the present study indicates that H. pylori does not have...

Nanoscale volcanoes: accretion of matter at ion-sculpted nanopores.

Science.gov (United States)

Mitsui, Toshiyuki; Stein, Derek; Kim, Young-Rok; Hoogerheide, David; Golovchenko, J A

2006-01-27

We demonstrate the formation of nanoscale volcano-like structures induced by ion-beam irradiation of nanoscale pores in freestanding silicon nitride membranes. Accreted matter is delivered to the volcanoes from micrometer distances along the surface. Volcano formation accompanies nanopore shrinking and depends on geometrical factors and the presence of a conducting layer on the membrane's back surface. We argue that surface electric fields play an important role in accounting for the experimental observations.

Effectiveness of an e-learning tool for education on pressure ulcer evaluation.

Science.gov (United States)

Morente, Laura; Morales-Asencio, José M; Veredas, Francisco J

2014-07-01

To evaluate the effectiveness of information and communication technologies in the undergraduate students' pressure ulcer training as a learning tool, compared with traditional teaching methods. Pressure ulcers constitute one of the great challenges faced by nursing professionals. Currently, pressure ulcer training is based on traditional on-campus teaching, involving lecture-style classes with frequent use of photographs of the wounds. This traditional training has some important weaknesses that can put the efficacy of the training at risk. A randomised controlled trial was developed including undergraduate nursing students. The intervention group used an adaptive self-learning e-learning tool developed by the research team (ePULab) for pressure ulcer assessment and treatment. The control group received a traditional on-campus class on the same topic. Pretest and post-test questionnaires were designed to assess the students' ability in pressure ulcer diagnosis and treatment. The educational intervention based on the use of the ePULab tool produced significantly better learning acquisition results than those obtained by traditional lecture-style classes: the total score improved in the control group from 8·23 (SD 1·23)-11·6 (SD 2·52) after the lecture, whereas in the intervention group, the knowledge score changed from 8·27 (SD 1·39)-15·83 (SD 2·52) (p = 0·01) with the use of ePULab. The results show a higher effectiveness of the devised e-learning approach for education on management of pressure ulcers. Our results reveal the suitability of the ePULab e-learning tool as an effective instrument for training on assessment of and treatment for pressure ulcers and its potential impact on clinical decision-making. © 2013 John Wiley & Sons Ltd.

Stomach specific polymeric low density microballoons as a vector for extended delivery of rabeprazole and amoxicillin for treatment of peptic ulcer.

Science.gov (United States)

Choudhary, Sandeep; Jain, Ashay; Amin, Mohd Cairul Iqbal Mohd; Mishra, Vijay; Agrawal, Govind P; Kesharwani, Prashant

2016-05-01

The study was intended to develop a new intra-gastric floating in situ microballoons system for controlled delivery of rabeprazole sodium and amoxicillin trihydrate for the treatment of peptic ulcer disease. Eudragit S-100 and hydroxypropyl methyl cellulose based low density microballoons systems were fabricated by employing varying concentrations of Eudragit S-100 and hydroxypropyl methyl cellulose, to which varying concentrations of drug was added, and formulated by stirring at various speed and time to optimize the process and formulation variable. The formulation variables like concentration and ratio of polymers significantly affected the in vitro drug release from the prepared floating device. The validation of the gastro-retentive potential of the prepared microballoons was carried out in rabbits by orally administration of microballoons formulation containing radio opaque material. The developed formulations showed improved buoyancy and lower ulcer index as compared to that seen with plain drugs. Ulcer protective efficacies were confirmed in ulcer-bearing mouse model. In conclusion, greater compatibility, higher gastro-retention and higher anti-ulcer activity of the presently fabricated formulations to improve potential of formulation for redefining ulcer treatment are presented here. These learning exposed a targeted and sustained drug delivery potential of prepared microballoons in gastric region for ulcer therapeutic intervention as corroborated by in vitro and in vivo findings and, thus, deserves further attention for improved ulcer treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

Study on the relationship between peripheral blood red blood cells imuno-function status and serum gastrin level in patients with peptic ulcer

International Nuclear Information System (INIS)

Li Qin; Fan Rong; Luo Honglai; Wang Ying; Tao Liangliang; Wang Zhenkai

2011-01-01

Objective: To explore the relationship between changes of peripheral blood red blood cells immuno-function status and serum gastrin level in patients with peptic ulcer. Methods: RBC immuno-function status was studied with immune methods and serum gastrin level was measured with RIA in 51 patients with peptic ulcer and compared with 35 healthy control group. Results: RBC-C3bRR percentage was significantly lower in patients with peptic ulcer than that in controls (P<0.01), while serum gastrin level was significantly higher (P<0.01). RBC-C3bRR was significantly nagatively correlated to serum gastrin (r=-0.3828, P<0.01). RBC-ICRRR percentage was prominently higher than that in healthy controls (P<0.01), and RBC-ICRRR was positively correlated to serum gastrin level (r=0.4185, P<0.01). Conclusion: There were disturbance of RBC immune-regulation with suppressed immune function and higher gastrin levels in patients with peptic ulcer. (authors)

Radioimmunoassay of gastrin level in duodenal ulcer, atrophic gostritis and Addison-Biermer's disease

International Nuclear Information System (INIS)

Hasik, J.; Kozal, H.; Kosowicz, J.; Hansz, J.

1975-01-01

Radioimmunoassay of gastrin level in the blood was performed in 20 controls, 12 patients with duodenal ulcer, 13 patients with atrophic gastritis and 14 patients with Addison-Biermer's disease. Gastrin level in the serum of the patients with duodenal ulcer did not differ significantly from that of controls. In atrophic gastritis and particularly in Addison-Biermer's disease gastrin level was found to be several times higher. This is probably a result of chronic gastrin secretion stimulation which is normally inhibited by gastric juice. (author)

Dietary Phytosterols Protective Against Peptic Ulceration

Science.gov (United States)

Tovey, Frank I; Capanoglu, Doga; Langley, G. John; Herniman, Julie M; Bor, Serhat; Ozutemiz, Omer; Hobsley, Michael; Bardhan, Karna Dev; Linclau, Bruno

2011-01-01

Background In developing countries the prevalence of duodenal ulceration is related to the staple diet and not to the prevalence of Helicobacter pylori. Experiments using animal peptic ulcer models show that the lipid fraction in foods from the staple diets of low prevalence areas gives protection against ulceration, including ulceration due to non-steroidal anti-inflammatory drugs (NSAIDs), and also promotes healing of ulceration. The lipid from the pulse Dolichos biflorus (Horse gram) was highly active and used for further investigations. Further experiments showed the phospholipids, sterol esters and sterols present in Horse gram lipid were gastroprotective. Dietary phospholipids are known to be protective, but the nature of protective sterols in staple diets is not known. The present research investigates the nature of the protective phytosterols. Methods Sterol fractions were extracted from the lipid in Dolichos biflorus and tested for gastroprotection using the rat ethanol model. The fractions showing protective activity were isolated and identification of the components was investigated by Gas Chromatography-Mass Spectrometry (GC-MS). Results The protective phytosterol fraction was shown to consist of stigmasterol, β-sitosterol and a third as yet unidentified sterol, isomeric with β-sitosterol. Conclusions Dietary changes, affecting the intake of protective phospholipids and phytosterols, may reduce the prevalence of duodenal ulceration in areas of high prevalence and may reduce the incidence of recurrent duodenal ulceration after healing and elimination of Helicobacter pylori infection. A combination of phospholipids and phytosterols, such as found in the lipid fraction of ulceroprotecive foods, may be of value in giving protection against the ulcerogenic effect of NSAIDs. PMID:27942332

Transcutaneous oxygen pressure measurement in diabetic foot ulcers: mean values and cut-point for wound healing.

Science.gov (United States)

Yang, Chuan; Weng, Huan; Chen, Lihong; Yang, Haiyun; Luo, Guangming; Mai, Lifang; Jin, Guoshu; Yan, Li

2013-01-01

The purpose of this study was to investigate mean values and cut-point of transcutaneous oxygen pressure (TcPO2) measurement in patients with diabetic foot ulcers. Prospective, descriptive study. Sixty-one patients with diabetes mellitus and foot ulcers comprised the sample. The research setting was Sun Yat-sen Memorial Hospital of SunYat-sen University, Guangzhou, China. Participants underwent transcutaneous oxygen (TcPO2) measurement at the dorsum of foot. Patients were classified into 3 groups according to clinical outcomes: (1) ulcers healed with intact skin group, (2) ulcer improved, and (3) ulcer failed to improve. TcPO2 was assessed and cut-points for predicting diabetic foot ulcer healing were calculated. Thirty-six patients healed with intact skin, 8 experienced improvement, and 17 showed no improvement. Mean TcPO2 levels were significantly higher (Pfoot ulcers. In contrast, all patients with TcPO2≥ 40 mmHg achieved wound closure. Measurement of TcPO2 in the supine position revealed a cut-point value of 25 mmHg as the best threshold for predicting diabetic foot ulcer healing; the area under the curve using this cut-point was 0.838 (95% confidence interval = 0.700-0.976). The sensitivity, specificity, positive predictive value, and negative predictive value for TxPO2 were 88.6%, 82.4%, 90.7%, and 72.2%, respectively. TcPO2≥ 40 mmHg was associated with diabetic foot ulcer healing, but a TcPO2≤ 10 mmHg was associated with failure of wound healing. We found that a cut-point of 25 mmHg was most predictive of diabetic foot ulcer healing.

Isotopic evolution of Mauna Loa volcano

International Nuclear Information System (INIS)

Kurz, M.D.; Kammer, D.P.

1991-01-01

In an effort to understand the temporal helium isotopic variations in Mauna Loa volcano, we have measured helium, strontium and lead isotopes in a suite of Mauna Loa lavas that span most of the subaerial eruptive history of the volcano. The lavas range in age from historical flows to Ninole basalt which are thought to be several hundred thousand years old. Most of the samples younger than 30 ka in age (Kau Basalt) are radiocarbon-dated flows, while the samples older than 30 ka are stratigraphically controlled (Kahuku and Ninole Basalt). The data reveal a striking change in the geochemistry of the lavas approximately 10 ka before present. The lavas older than 10 ka are characterized by high 3 He/ 4 He (≅ 16-20 times atmospheric), higher 206 Pb/ 204 Pb (≅ 18.2), and lower 87 Sr/ 86 Sr(≅ 0.70365) ratios than the younger Kau samples (having He, Pb and Sr ratios of approximately 8.5 x atmospheric, 18.1 and 0.70390, respectively). The historical lavas are distinct in having intermediate Sr and Pb isotopic compositions with 3 He/ 4 He ratios similar to the other young Kau basalt (≅ 8.5 x atmospheric). The isotopic variations are on a shorter time scale (100 to 10,000 years) than has previously been observed for Hawaiian volcanoes, and demonstrate the importance of geochronology and stratigraphy to geochemical studies. The data show consistency between all three isotope systems, which suggests that the variations are not related to magma chamber degassing processes, and that helium is not decoupled from the other isotopes. However, the complex temporal evolution suggests that three distinct mantle sources are required to explain the isotopic data. Most of the Mauna Loa isotopic variations could be explained by mixing between a plume type source, similar to Loihi, and an asthenospheric source with helium isotopic composition close to MORB and elevated Sr isotopic values. (orig./WL)

Pressure ulcer prevention in frail older people.

Science.gov (United States)

Barry, Maree; Nugent, Linda

2015-12-16

Pressure ulcers are painful and cause discomfort, have a negative effect on quality of life, and are costly to treat. The incidence and severity of preventable pressure ulcers is an important indicator of quality of care; it is essential that healthcare providers monitor prevalence and incidence rates to ensure that care strategies implemented are effective. Frail older people are at increased risk of developing pressure ulcers. This article discusses the complexities of preventing pressure ulcers in frail older people and emphasises the importance of structured educational programmes that incorporate effective clinical leadership and multidisciplinary teamwork.

Matrix metalloproteinase-3 promoter polymorphisms but not dupA-H. pylori correlate to duodenal ulcers in H. pylori-infected females.

Science.gov (United States)

Yeh, Yi-Chun; Cheng, Hsiu-Chi; Chang, Wei-Lun; Yang, Hsiao-Bai; Sheu, Bor-Shyang

2010-08-13

This study investigated if the H. pylori dupA genotype and certain host single nucleotide polymorphisms (SNPs) of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), including MMP-3, MMP-7, MMP-9, TIMP-1 and TIMP-2, might correlate with ulcer risk of H. pylori-infected Taiwanese patients. Of the 549 H. pylori-infected patients enrolled, 470 patients (265 with gastritis, 118 with duodenal ulcer, and 87 with gastric ulcer) received SNPs analysis of MMP-3-1612 6A > 5A, MMP-7-181 A > G, MMP-9exon 6 A > G, TIMP-1372 T > C and TIMP-2-418 G > C by PCR-RFLP. The 181 collected H. pylori isolates were detected for the dupA genotype by PCR. The rates of dupA-positive H. pylori infection were similar among patients with duodenal ulcer (22.8%), gastric ulcer (20.0%), and gastritis (25.5%) (p > 0.05). Males had higher rates of duodenal ulcer and gastric ulcer than females (p dupA-status, may correlate with susceptibility to duodenal ulcer after H. pylori infection in Taiwanese females.

CONTACT LENS RELATED CORNEAL ULCER

Directory of Open Access Journals (Sweden)

AGARWAL P

2010-01-01

Full Text Available A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns is the increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specific instruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are:overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. The presenting symptoms of contact lens related corneal ulcers include eye discomfort, foreign body sensation and lacrimation. More serious symptoms are redness (especially circum-corneal injection, severe pain, photophobia, eye discharge and blurring of vision. The diagnosis is established by a thorough slit lamp microscopic examination with fluorescein staining and corneal scraping for Gram stain and culture of the infective organism. Delay in diagnosing and treatment can cause permanent blindness, therefore an early referral to ophthalmologist and commencing of antimicrobial therapy can prevent visual loss.

[Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease].

Science.gov (United States)

Shim, Young Kwang; Kim, Nayoung

2016-06-25

Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation. In addition, low dose aspirin is employed as an anti-coagulant for those who have suffered or are at high risk of ischemic stroke and cardiovascular disease. However, NSAIDs and aspirin are injurious to mucosa of stomach and duodenum. NSAID-induced inhibition of mucosal prostaglandin synthesis is thought to be a major mechanism of gastrointestinal mucosal injury. The proportion of elderly has increased rapidly in Korea, with the proportion over 65 years old expected to be 24.3% in 2030. In this higher-risk population, the strategy to reduce the incidence of NSAID-related peptic ulcers and complications such as bleeding, obstruction and perforation is very important. Proton pump inhibitors (PPIs) with cyclooxygenase-2 inhibitor can be used for reducing the risk of NSAID-related ulcers and upper gastrointestinal (GI) complications. However, continuous use of PPI has several problems. In addition, NSAID-related problems in the lower GI tract have increased, in contrast to the decrease of NSAID-related upper GI disease. The aim of this review is to provide an evidence-based knowledge regarding the mechanism, complications of treatment, and prevention strategies for NSAID- or aspirin-related peptic ulcer disease in Korea.

Prevention and treatment of pressure ulcers by newest recommendations from European Pressure Ulcer Advisory Panel (EPUAP: practical reference guide for GPs

Directory of Open Access Journals (Sweden)

Jakub Taradaj

2017-03-01

Full Text Available The guideline titled “Prevention and treatment of pressure ulcers: clinical practice guideline” is the result of a collaborative effort between the National Pressure Ulcer Advisory Panel (NPUAP, European Pressure Ulcer Advisory Panel (EPUAP and Pan Pacific Pressure Injury Alliance (PPPIA. A comprehensive literature review was conducted on pressure ulcer prevention and treatment. Rigorous scientific methodology was used to appraise available research and make evidence-based recommendations for the prevention and treatment of pressure ulcers. Draft guidelines were made available to 986 invited individual stakeholders and organizations or societies, and the feedback of the stakeholders was taken under consideration by the developers of the guideline. The guideline includes 575 explicit recommendations and/or research summaries for multidisciplinary pressure ulcer topics.

Work in progress. Gastrointestinal ulcerations: detection using a technetium-99m-labeled ulcer-avid agent

International Nuclear Information System (INIS)

Vasquez, T.E.; Bridges, R.L.; Braunstein, P.; Jansholt, A.L.; Meshkinpour, H.

1983-01-01

Technetium-99m-labeled sucralfate, an ulcer-avid material, was shown in preliminary animal and human studies to be stable in vivo with good sensitivity. Eight experimentally produced discrete gastric ulcers in three rabbits were visualized using this material. Of seven human studies, four studies were true-positive and three were true-negative. It is suggested that Tc-99m-labeled sucralfate may prove to have significant clinical advantages for the evaluation of gastrointestinal ulcer disease and other diseases that are associated with loss of mucosal integrity. The method for labeling sucralfate with Tc-99m was developed by the authors

The diminished expression of proangiogenic growth factors and their receptors in gastric ulcers of cirrhotic patients.

Science.gov (United States)

Luo, Jiing-Chyuan; Peng, Yen-Ling; Hou, Ming-Chih; Huang, Kuang-Wei; Huang, Hui-Chun; Wang, Ying-Wen; Lin, Han-Chieh; Lee, Fa-Yauh; Lu, Ching-Liang

2013-01-01

The pathogenesis of the higher occurrence of peptic ulcer disease in cirrhotic patients is complex. Platelets can stimulate angiogenesis and promote gastric ulcer healing. We compared the expressions of proangiogenic growth factors and their receptors in the gastric ulcer margin between cirrhotic patients with thrombocytopenia and those of non-cirrhotic patients to elucidate possible mechanisms. Eligible cirrhotic patients (n = 55) and non-cirrhotic patients (n = 55) who had gastric ulcers were enrolled. Mucosa from the gastric ulcer margin and non-ulcer areas were sampled and the mRNA expressions of the proangiogenic growth factors (vascular endothelial growth factor [VEGF], platelet derived growth factor [PDGF], basic fibroblast growth factor [bFGF]) and their receptors (VEGFR1, VEGFR2, PDGFRA, PDGFRB, FGFR1, FGFR2) were measured and compared. Platelet count and the expressions of these growth factors and their receptors were correlated with each other. The two groups were comparable in terms of gender, ulcer size and infection rate of Helicobacter pylori. However, the cirrhotic group were younger in age, had a lower platelet count than those in the non-cirrhotic group (pexpressions of PDGFB, VEGFR2, FGFR1, and FGFR2 in gastric ulcer margin when compared with those of the non-cirrhotic patients (pexpressions of PDGFB and VEGFR2, FGFR1, and FGFR2 were well correlated with the degree of thrombocytopenia in these cirrhotic patients (ρ>0.5, pimplied that diminished activity of proangiogenic factors and their receptors may contribute to the pathogenesis of gastric ulcers in cirrhotic patients.

Nurses' attitudes towards pressure ulcer prevention in Turkey.

Science.gov (United States)

Aslan, Arzu; Yavuz van Giersbergen, Meryem

2016-02-01

Pressure ulcers remain a major problem in healthcare system. Pressure ulcer incidence is widely accepted as an indicator for the quality of care. Positive attitudes towards pressure ulcer prevention have positive impacts on preventive care. The aim of this study was to identify nurses' attitude towards pressure ulcer prevention. The study design was descriptive. The study was carried out in a university hospital in Izmir, Turkey. The study population consisted of 660 nurses who work in medical and surgical clinics and intensive care units. The study sample consisted of 426 nurses who agreed to participate. Attitude towards Pressure Ulcer Prevention Instrument was used in order to evaluate nurses' attitudes. Written permissions for ethical considerations and Attitude towards Pressure Ulcer Prevention Instrument permission were obtained. Data were collected between June and July 2014. The statistics program SPSS 18 packaged software was used in the analyses of data. The average age of the nurses who took part in the study was 31.86 ± 7.09 years and the average work experience was 8.88 ± 7.41 years; 36.9% (n: 157) were working in intensive care units. The nurses' average score on the Attitude towards Pressure Ulcer Prevention Instrument was 43.74 ± 4.29 (84.12%). It was seen that the attitudes of the nurses towards the prevention of pressure ulcers was positive. To read guidelines and training time about pressure ulcer prevention affect positively attitudes towards the prevention of pressure ulcers. Copyright © 2015 Tissue Viability Society. Published by Elsevier Ltd. All rights reserved.

Geochemical studies on island arc volcanoes

International Nuclear Information System (INIS)

Notsu, Kenji

1998-01-01

This paper summarizes advances in three topics of geochemical studies on island arc volcanoes, which I and my colleagues have been investigating. First one is strontium isotope studies of arc volcanic rocks mainly from Japanese island arcs. We have shown that the precise spatial distribution of the 87 Sr/ 86 Sr ratio reflects natures of the subduction structure and slab-mantle interaction. Based on the 87 Sr/ 86 Sr ratio of volcanic rocks in the northern Kanto district, where two plates subduct concurrently with different directions, the existence of an aseismic portion of the Philippine Sea plate ahead of the seismic one was suggested. Second one is geochemical monitoring of active arc volcanoes. 3 He/ 4 He ratio of volcanic volatiles was shown to be a good indicator to monitor the behavior of magma: ascent and drain-back of magma result in increase and decrease in the ratio, respectively. In the case of 1986 eruptions of Izu-Oshima volcano, the ratio began to increase two months after big eruptions, reaching the maximum and decreased. Such delayed response is explained in terms of travelling time of magmatic helium from the vent area to the observation site along the underground steam flow. Third one is remote observation of volcanic gas chemistry of arc volcanoes, using an infrared absorption spectroscopy. During Unzen eruptions starting in 1990, absorption features of SO 2 and HCl of volcanic gas were detected from the observation station at 1.3 km distance. This was the first ground-based remote detection of HCl in volcanic gas. In the recent work at Aso volcano, we could identify 5 species (CO, COS, CO 2 , SO 2 and HCl) simultaneously in the volcanic plume spectra. (author)

Constructing a reference tephrochronology for Augustine Volcano, Alaska

Science.gov (United States)

Wallace, Kristi; Coombs, Michelle L.

2013-01-01

Augustine Volcano is the most historically active volcano in Alaska's populous Cook Inlet region. Past on-island work on pre-historic tephra deposits mainly focused on using tephra layers as markers to help distinguish among prevalent debris-avalanche deposits on the island (Waitt and Beget, 2009, USGS Prof Paper 1762), or as source material for petrogenetic studies. No comprehensive reference study of tephra fall from Augustine Volcano previously existed. Numerous workers have identified Holocene-age tephra layers in the region surrounding Augustine Island, but without well-characterized reference deposits, correlation back to the source volcano is difficult. The purpose of this detailed tephra study is to provide a record of eruption frequency and magnitude, as well as to elucidate physical and chemical characteristics for use as reference standards for comparison with regionally distributed Augustine tephra layers. Whole rock major- and trace-element geochemistry, deposit componentry, and field context are used to correlate tephra units on the island where deposits are coarse grained. Major-element glass geochemistry was collected for use in correlating to unknown regional tephra. Due to the small size of the volcanic island (9 by 11 km in diameter) and frequent eruptive activity, on-island exposures of tephra deposits older than a couple thousand years are sparse, and the lettered Tephras B, M, C, H, I, and G of Waitt and Beget (2009) range in age from 370-2200 yrs B.P. There are, however, a few exposures on the south side of the volcano, within about 2 km of the vent, where stratigraphic sections that extend back to the late Pleistocene glaciation include coarse pumice-fall deposits. We have linked the letter-named tephras from the coast to these higher exposures on the south side using physical and chemical characteristics of the deposits. In addition, these exposures preserve at least 5 older major post-glacial eruptions of Augustine. These ultra

Soil gas geochemistry in relation to eruptive fissures on Timanfaya volcano, Lanzarote Island (Canary Islands, Spain)

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Padrón, Eleazar; Padilla, Germán; Hernández, Pedro A.; Pérez, Nemesio M.; Calvo, David; Nolasco, Dácil; Barrancos, José; Melián, Gladys V.; Dionis, Samara; Rodríguez, Fátima

2013-01-01

We report herein the first results of an extensive soil gas survey performed on Timanfaya volcano on May 2011. Soil gas composition at Timanfaya volcano indicates a main atmospheric source, slightly enriched in CO2 and He. Soil CO2 concentration showed a very slight deep contribution of the Timanfaya volcanic system, with no clear relation to the main eruptive fissures of the studied area. The existence of soil helium enrichments in Timanfaya indicates a shallow degassing of crustal helium and other possible deeper sources probably form cooling magma bodies at depth. The main soil helium enrichments were observed in good agreement with the main eruptive fissures of the 1730-36 eruption, with the highest values located at those areas with a higher density of recent eruptive centers, indicating an important structural control for the leakage of helium at Timanfaya volcano. Atmospheric air slightly polluted by deep-seated helium emissions, CO2 degassed from a cooling magma body, and biogenic CO2, might be the most plausible explanation for the existence of soil gas. Helium is a deep-seated gas, exhibiting important emission rates along the main eruptive fissure of the 1730-36 eruption of Timanfaya volcano.

Tsunamis generated by eruptions from mount st. Augustine volcano, alaska.

Science.gov (United States)

Kienle, J; Kowalik, Z; Murty, T S

1987-06-12

During an eruption of the Alaskan volcano Mount St. Augustine in the spring of 1986, there was concern about the possibility that a tsunami might be generated by the collapse of a portion of the volcano into the shallow water of Cook Inlet. A similar edifice collapse of the volcano and ensuing sea wave occurred during an eruption in 1883. Other sea waves resulting in great loss of life and property have been generated by the eruption of coastal volcanos around the world. Although Mount St. Augustine remained intact during this eruptive cycle, a possible recurrence of the 1883 events spurred a numerical simulation of the 1883 sea wave. This simulation, which yielded a forecast of potential wave heights and travel times, was based on a method that could be applied generally to other coastal volcanos.

Attitudes toward clinical and traditional treatment for the Buruli ulcer ...

African Journals Online (AJOL)

Satisfaction with clinical treatment is not higher than with traditional medicine; people tend to turn to clinical medicine after traditional treatments fail. Few social stigmas result from the disease other than avoidance of the unsightly ulcer and the unpleasant smell, and among children, some teasing. The major concern ...

Automatic Classification of volcano-seismic events based on Deep Neural Networks.

Science.gov (United States)

Titos Luzón, M.; Bueno Rodriguez, A.; Garcia Martinez, L.; Benitez, C.; Ibáñez, J. M.

2017-12-01

Seismic monitoring of active volcanoes is a popular remote sensing technique to detect seismic activity, often associated to energy exchanges between the volcano and the environment. As a result, seismographs register a wide range of volcano-seismic signals that reflect the nature and underlying physics of volcanic processes. Machine learning and signal processing techniques provide an appropriate framework to analyze such data. In this research, we propose a new classification framework for seismic events based on deep neural networks. Deep neural networks are composed by multiple processing layers, and can discover intrinsic patterns from the data itself. Internal parameters can be initialized using a greedy unsupervised pre-training stage, leading to an efficient training of fully connected architectures. We aim to determine the robustness of these architectures as classifiers of seven different types of seismic events recorded at "Volcán de Fuego" (Colima, Mexico). Two deep neural networks with different pre-training strategies are studied: stacked denoising autoencoder and deep belief networks. Results are compared to existing machine learning algorithms (SVM, Random Forest, Multilayer Perceptron). We used 5 LPC coefficients over three non-overlapping segments as training features in order to characterize temporal evolution, avoid redundancy and encode the signal, regardless of its duration. Experimental results show that deep architectures can classify seismic events with higher accuracy than classical algorithms, attaining up to 92% recognition accuracy. Pre-training initialization helps these models to detect events that occur simultaneously in time (such explosions and rockfalls), increase robustness against noisy inputs, and provide better generalization. These results demonstrate deep neural networks are robust classifiers, and can be deployed in real-environments to monitor the seismicity of restless volcanoes.

Soil radon response around an active volcano

International Nuclear Information System (INIS)

Segovia, N.; Valdes, C.; Pena, P.; Mena, M.; Tamez, E.

2001-01-01

Soil radon behavior related to the volcanic eruptive period 1997-1999 of Popocatepetl volcano has been studied as a function of the volcanic activity. Since the volcano is located 60 km from Mexico City, the risk associated with an explosive eruptive phase is high and an intense surveillance program has been implemented. Previous studies in this particular volcano showed soil radon pulses preceding the initial phase of the eruption. The radon survey was performed with LR-115 track detectors at a shallow depth and the effect of the soil moisture during the rainy season has been observed on the detectors response. In the present state of the volcanic activity the soil radon behavior has shown more stability than in previous eruptive stages

Volcanic spreading forcing and feedback in geothermal reservoir development, Amiata Volcano, Italia

Science.gov (United States)

Borgia, Andrea; Mazzoldi, Alberto; Brunori, Carlo Alberto; Allocca, Carmine; Delcroix, Carlo; Micheli, Luigi; Vercellino, Alberto; Grieco, Giovanni

2014-09-01

We made a stratigraphic, structural and morphologic study of the Amiata Volcano in Italy. We find that the edifice is dissected by intersecting grabens that accommodate the collapse of the higher sectors of the volcano. In turn, a number of compressive structures and diapirs exist around the margin of the volcano. These structures create an angular drainage pattern, with stream damming and captures, and a set of lakes within and around the volcano. We interpret these structures as the result of volcanic spreading of Amiata on its weak substratum, formed by the late Triassic evaporites (Burano Anhydrites) and the Middle-Jurassic to Early-Cretaceous clayey chaotic complexes (Ligurian Complex). Regional doming created a slope in the basement facilitating the outward flow and spreading of the ductile layers forced by the volcanic load. We model the dynamics of spreading with a scaled lubrication approximation of the Navier Stokes equations, and numerically study a set of solutions. In the model we include simple functions for volcanic deposition and surface erosion that change the topography over time. Scaling indicates that spreading at Amiata could still be active. The numerical solution shows that, as the central part of the edifice sinks into the weak basement, diapiric structures of the underlying formations form around the base of the volcano. Deposition of volcanic rocks within the volcano and surface erosion away from it both enhance spreading. In addition, a sloping basement may constitute a trigger for spreading and formation of trains of adjacent diapirs. As a feedback, the hot hydrothermal fluids decrease the shear strength of the anhydrites facilitating the spreading process. Finally, we observe that volcanic spreading has created ideal heat traps that constitute todays' exploited geothermal fields at Amiata. Normal faults generated by volcanic spreading, volcanic conduits, and direct contact between volcanic rocks (which host an extensive fresh

The PU-PROM: A patient-reported outcome measure for peptic ulcer disease.

Science.gov (United States)

Liu, Na; Lv, Jing; Liu, Jinchun; Zhang, Yanbo

2017-12-01

Patient-reported outcome measure (PROM) conceived to enable description of treatment-related effects, from the patient perspective, bring the potential to improve in clinical research, and to provide patients with accurate information. Therefore, the aim of this study was to develop a patient-centred peptic ulcer patient-reported outcome measure (PU-PROM) and evaluate its reliability, validity, differential item functioning (DIF) and feasibility. To develop a conceptual framework and item pool for the PU-PROM, we performed a literature review and consulted other measures created in China and other countries. Beyond that, we interviewed 10 patients with peptic ulcers, and consulted six key experts to ensure that all germane parameters were included. In the first item selection phase, classical test theory and item response theory were used to select and adjust items to shape the preliminary measure completed by 130 patients and 50 controls. In the next phase, the measure was evaluated used the same methods with 492 patients and 124 controls. Finally, we used the same population in the second item reselection to assess the reliability, validity, DIF and feasibility of the final measure. The final peptic ulcer PRO measure comprised four domains (physiology, psychology, society and treatment), with 11 subdomains, and 54 items. The Cronbach's α coefficient of each subdomain for the measure was >0.800. Confirmatory factory analysis indicated that the construct validity fulfilled expectations. Model fit indices, such as RMR, RMSEA, NFI, NNFI, CFI and IFI, showed acceptable fit. The measure showed a good response rate. The peptic ulcer PRO measure had good reliability, validity, DIF and feasibility, and can be used as a clinical research evaluation instrument with patients with peptic ulcers to assess their condition focus on treatment. This measure may also be applied in other health areas, especially in clinical trials of new drugs, and may be helpful in clinical

Current X-ray diagnosis of peptic ulcer

International Nuclear Information System (INIS)

Antonovich, V.B.

1984-01-01

Classification of peptic ulcer symptoms is suggested on the basis of practical experience. The data on advisability of preserving direct symptom of peptic ulcer - ''niche'' and indirect symptoms are presented. Morphological and functional characteristics must be distinguished in the group of indrect symptoms. The scheme of X-ray semiotics of peptic ulcer is presented

Predicting the Timing and Location of the next Hawaiian Volcano

Science.gov (United States)

Russo, Joseph; Mattox, Stephen; Kildau, Nicole

2010-01-01

The wealth of geologic data on Hawaiian volcanoes makes them ideal for study by middle school students. In this paper the authors use existing data on the age and location of Hawaiian volcanoes to predict the location of the next Hawaiian volcano and when it will begin to grow on the floor of the Pacific Ocean. An inquiry-based lesson is also…

Diabetes: foot ulcers and amputations.

Science.gov (United States)

Hunt, Dereck L

2011-08-26

Diabetic foot ulceration is full-thickness penetration of the dermis of the foot in a person with diabetes. Severity is classified using the Wagner system, which grades it from 1 to 5. The annual incidence of ulcers among people with diabetes is 2.5% to 10.7% in resource-rich countries, and the annual incidence of amputation for any reason is 0.25% to 1.8%. We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of interventions to prevent foot ulcers and amputations in people with diabetes? What are the effects of treatments in people with diabetes with foot ulceration? We searched: Medline, Embase, The Cochrane Library, and other important databases up to September 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 50 systematic reviews and RCTs that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. In this systematic review, we present information relating to the effectiveness and safety of the following interventions: debridement, human cultured dermis, human skin equivalent, patient education, pressure off-loading with felted foam or pressure-relief half-shoe, pressure off-loading with total-contact or non-removable casts, screening and referral to foot-care clinics, systemic hyperbaric oxygen for non-infected ulcers, systemic hyperbaric oxygen in infected ulcers, therapeutic footwear, topical growth factors, and wound dressings.

Overview for geologic field-trip guides to volcanoes of the Cascades Arc in northern California

Science.gov (United States)

Muffler, L. J. Patrick; Donnelly-Nolan, Julie M.; Grove, Timothy L.; Clynne, Michael A.; Christiansen, Robert L.; Calvert, Andrew T.; Ryan-Davis, Juliet

2017-08-15

The California Cascades field trip is a loop beginning and ending in Portland, Oregon. The route of day 1 goes eastward across the Cascades just south of Mount Hood, travels south along the east side of the Cascades for an overview of the central Oregon volcanoes (including Three Sisters and Newberry Volcano), and ends at Klamath Falls, Oregon. Day 2 and much of day 3 focus on Medicine Lake Volcano. The latter part of day 3 consists of a drive south across the Pit River into the Hat Creek Valley and then clockwise around Lassen Volcanic Center to the town of Chester, California. Day 4 goes from south to north across Lassen Volcanic Center, ending at Burney, California. Day 5 and the first part of day 6 follow a clockwise route around Mount Shasta. The trip returns to Portland on the latter part of day 6, west of the Cascades through the Klamath Mountains and the Willamette Valley. Each of the three sections of this guidebook addresses one of the major volcanic regions: Lassen Volcanic Center (a volcanic field that spans the volcanic arc), Mount Shasta (a fore-arc stratocone), and Medicine Lake Volcano (a rear-arc, shield-shaped edifice). Each section of the guide provides (1) an overview of the extensive field and laboratory studies, (2) an introduction to the literature, and (3) directions to the most important and accessible field localities. The field-trip sections contain far more stops than can possibly be visited in the actual 6-day 2017 IAVCEI excursion from Portland. We have included extra stops in order to provide a field-trip guide that will have lasting utility for those who may have more time or may want to emphasize one particular volcanic area.

Bodily pain intensity in nursing home residents with pressure ulcers: analysis of national minimum data set 3.0.

Science.gov (United States)

Ahn, Hyochol; Stechmiller, Joyce; Fillingim, Roger; Lyon, Debra; Garvan, Cynthia

2015-06-01

Clinical reports suggest that superficial pressure ulcers produce pain, but that pain decreases as the wound advances in stage. This study of the relationship between pressure ulcer stage and bodily pain intensity in nursing home residents was a secondary analysis of the national Minimum Data Set 3.0 assessment data in long-term care facilities, collected from nursing home residents at least 65 years of age. Data were examined from residents with pressure ulcers who completed a bodily pain intensity interview between January and March 2012 (N = 41,680) as part of the MDS comprehensive assessment. After adjusting for other variables (e.g., cognition, functional impairment, presence of comorbidities, use of scheduled pain medication, and sociodemographic variables), bodily pain intensity for those with more severe pressure ulcers in comparison to those with Stage I ulcers was higher by 11% (Stage II), 14% (Stage III), 24% (Stage IV), and 22% (suspected deep tissue injury). Because multivariate analysis showed that greater bodily pain intensity was associated with an advanced stage of pressure ulcer, health care providers should assess bodily pain intensity and order appropriate pain management for nursing home residents with pressure ulcers, particularly for those with advanced pressure ulcers who are vulnerable to greater bodily pain intensity. © 2015 Wiley Periodicals, Inc.

Preliminary Evaluation of the Effects of Buried Volcanoes on Estimates of Volcano Probability for the Proposed Repository Site at Yucca Mountain, Nevada

Science.gov (United States)

Hill, B. E.; La Femina, P. C.; Stamatakos, J.; Connor, C. B.

2002-12-01

Probability models that calculate the likelihood of new volcano formation in the Yucca Mountain (YM) area depend on the timing and location of past volcanic activity. Previous spatio-temporal patterns indicated a 10-4 to 10-3 probability of volcanic disruption of the proposed radioactive waste repository site at YM during the 10,000 year post-closure performance period (Connor et al. 2000, JGR 105:1). A recent aeromagnetic survey (Blakely et al. 2000, USGS OFR 00-188), however, identified up to 20 anomalies in alluvium-filled basins, which have characteristics indicative of buried basalt (O'Leary et al. 2002, USGS OFR 02-020). Independent evaluation of these data, combined with new ground magnetic surveys, shows that these anomalies may represent at least ten additional buried basaltic volcanoes, which have not been included in previous probability calculations. This interpretation, if true, nearly doubles the number of basaltic volcanoes within 30 km [19 mi] of YM. Moreover, the magnetic signature of about half of the recognized basaltic volcanoes in the YM area cannot be readily identified in areas where bedrock also produces large amplitude magnetic anomalies, suggesting that additional volcanoes may be present but undetected in the YM area. In the absence of direct age information, we evaluate the potential effects of alternative age assumptions on spatio-temporal probability models. Interpreted burial depths of >50 m [164 ft] suggest ages >2 Ma, based on sedimentation rates typical for these alluvial basins (Stamatakos et al., 1997, J. Geol. 105). Defining volcanic events as individual points, previous probability models generally used recurrence rates of 2-5 volcanoes/million years (v/Myr). If the identified anomalies are buried volcanoes that are all >5 Ma or uniformly distributed between 2-10 Ma, calculated probabilities of future volcanic disruption at YM change by <30%. However, a uniform age distribution between 2-5 Ma for the presumed buried volcanoes

Current X-ray diagnosis of peptic ulcer

Energy Technology Data Exchange (ETDEWEB)

Antonovich, V.B. (Tsentral' nyj Inst. Usovershenstvovaniya Vrachej, Moscow (USSR))

Classification of peptic ulcer symptoms is suggested on the basis of practical experience. The data on advisability of preserving direct symptom of peptic ulcer - ''niche'' and indirect symptoms are presented. Morphological and functional characteristics must be distinguished in the group of indrect symptoms. The scheme of X-ray semiotics of peptic ulcer is presented.

5-Aminosalicylates reduce the risk of colorectal neoplasia in patients with ulcerative colitis: an updated meta-analysis.

Directory of Open Access Journals (Sweden)

Li-Na Zhao

Full Text Available BACKGROUND: Although the chemopreventive effect of 5-aminosalicylates on patients with ulcerative colitis has been extensively studied, the results remain controversial. This updated review included more recent studies and evaluated the effectiveness of 5-aminosalicylates use on colorectal neoplasia prevention in patients with ulcerative colitis. METHODS: Up to July 2013, we searched Medline, Embase, Web of Science, Cochrane CENTRAL, and SinoMed of China for all relevant observational studies (case-control and cohort about the effect of 5-aminosalicylates on the risk of colorectal neoplasia among patients with ulcerative colitis. The Newcastle-Ottawa Scale was used to assess the quality of studies. Adjusted odds ratios (ORs were extracted from each study. A random-effects model was used to generate pooled ORs and 95% confidence intervals (95%CI. Publication bias and heterogeneity were assessed. RESULTS: Seventeen studies containing 1,508 cases of colorectal neoplasia and a total of 20,193 subjects published from 1994 to 2012 were analyzed. 5-aminosalicylates use was associated with a reduced risk of colorectal neoplasia in patients with ulcerative colitis (OR 0.63; 95%CI 0.48-0.84. Pooled OR of a higher average daily dose of 5-aminosalicylates (sulfasalazine ≥ 2.0 g/d, mesalamine ≥ 1.2 g/d was 0.51 [0.35-0.75]. Pooled OR of 5-aminosalicylates use in patients with extensive ulcerative colitis was 1.00 [0.53-1.89]. CONCLUSION: Our pooled results indicated that 5-aminosalicylates use was associated with a reduced risk of colorectal neoplasia in patients with ulcerative colitis, especially in the cases with a higher average daily dose of 5-aminosalicylates use. However, the chemopreventive benefit of 5-aminosalicylates use in patients with extensive ulcerative colitis was limited.

High probability of healing without amputation of plantar forefoot ulcers in patients with diabetes.

Science.gov (United States)

Örneholm, Hedvig; Apelqvist, Jan; Larsson, Jan; Eneroth, Magnus

2015-01-01

Diabetic foot ulcer is an important entity which in many cases is the first serious complication in diabetes. Although a plantar forefoot location is common, there are few studies on larger cohorts and in such studies there is often a combination of various types of ulcer and ulcer locations. The purpose of this study is to discern the outcome of plantar forefoot ulcers and their specific characteristics in a large cohort. All patients (n = 770), presenting with a plantar forefoot ulcer at a multidisciplinary diabetes foot clinic from January 1, 1983 to December 31, 2012 were considered for the study. Seven hundred one patients (median age 67 [22-95]) fulfilled the inclusion criteria and were followed according to a preset protocol until final outcome (healing or death). Severe peripheral vascular disease was present in 26% of the patients and 14% had evidence of deep infection upon arrival at the foot clinic. Fifty-five percent (385/701) of the patients healed without foot surgery, 25% (173/701) healed after major debridement, 9% (60/701) healed after minor or major amputation and 12% (83/701) died unhealed. Median healing time was 17 weeks. An ulcer classified as Wagner grade 1 or 2 at inclusion and independent living were factors associated with a higher healing rate. Seventy-nine percent of 701 patients with diabetes and a plantar forefoot ulcer treated at a multidisciplinary diabetes foot clinic healed without amputation. For one third some form of foot surgery was needed to achieve healing. © 2015 by the Wound Healing Society.

Buruli Ulcer (Mycobacterium ulcerans Infection)

Science.gov (United States)

... detail/buruli-ulcer-(mycobacterium-ulcerans-infection)","@context":"http://schema.org","@type":"Article"}; العربية 中文 français русский español ... Buruli ulcer on a regular basis to share information, coordinate disease control and research efforts, and monitor ...

Airborne VLF survey of Izu-Oshima volcano

Energy Technology Data Exchange (ETDEWEB)

Murakami, Yutaka; Yukutake, Takeshi

1988-05-17

Resistivity distribution in underground indicates anomaly in some cases due to volcanic activity, airborne VLF survey of Izu-Oshima volcano in whole area was carried out by measurement of the anomalous vertical magnetic field. The flight direction was determined with reference to both of the transmitter direction of the VLF waves and the running direction of the geologic formation. The flight altitude and the flight lines spacing were 100 m and 200 m respectively. Typical profiles of four lines of measurement were investigated. The resistivity anomalies were indicated corresponding to the position of known geologic fissure line, the lip of the caldera, the line of the craters and side volcanos. Several anomalous trends were detected by the contour drawing of the Fraser filter output. The detected results were as follow: new volcanos with the resistivity anomaly, the resistivity anomalies spread to the north-northwest from Goshinka jaya, the anomalies due to flowed lava, the anomalies by encroached water from the caldera wall, the effects from side volcanoes and so on. The resistivity anomalies by airborne VLF survey correspond to the known volcanic activities, and they are useful for elucidation of the underground volcanism. (6 figs, 4 refs)

Effects of Host-rock Fracturing on Elastic-deformation Source Models of Volcano Deflation.

Science.gov (United States)

Holohan, Eoghan P; Sudhaus, Henriette; Walter, Thomas R; Schöpfer, Martin P J; Walsh, John J

2017-09-08

Volcanoes commonly inflate or deflate during episodes of unrest or eruption. Continuum mechanics models that assume linear elastic deformation of the Earth's crust are routinely used to invert the observed ground motions. The source(s) of deformation in such models are generally interpreted in terms of magma bodies or pathways, and thus form a basis for hazard assessment and mitigation. Using discontinuum mechanics models, we show how host-rock fracturing (i.e. non-elastic deformation) during drainage of a magma body can progressively change the shape and depth of an elastic-deformation source. We argue that this effect explains the marked spatio-temporal changes in source model attributes inferred for the March-April 2007 eruption of Piton de la Fournaise volcano, La Reunion. We find that pronounced deflation-related host-rock fracturing can: (1) yield inclined source model geometries for a horizontal magma body; (2) cause significant upward migration of an elastic-deformation source, leading to underestimation of the true magma body depth and potentially to a misinterpretation of ascending magma; and (3) at least partly explain underestimation by elastic-deformation sources of changes in sub-surface magma volume.

Pressure ulcer prevention in high-risk postoperative cardiovascular patients.

Science.gov (United States)

Jackson, Melissa; McKenney, Teresa; Drumm, Jennifer; Merrick, Brian; LeMaster, Tamara; VanGilder, Catherine

2011-08-01

Little has been published about how to prevent pressure ulcers in severely debilitated, immobile patients in intensive care units. To present a possible prevention strategy for postoperative cardiovascular surgery patients at high risk for development of pressure ulcers. Staff chose to implement air fluidized therapy beds, which provide maximal immersion and envelopment as a measure for preventing pressure ulcers in patients who (1) required vasopressors for at least 24 hours and (2) required mechanical ventilation for at least 24 hours postoperatively. Only 1 of 27 patients had a pressure ulcer develop while on the air fluidized therapy bed (February 2008 through August 2008), and that ulcer was only a stage I ulcer, compared with 40 ulcers in 25 patients before the intervention. Patients spent a mean of 7.9 days on the mattress, and the cost of bed rental was approximately $18000, which was similar to the cost of treatment of 1 pressure ulcer in stage III or IV (about $40000) and was considered cost-effective.

Massage therapy for preventing pressure ulcers.

Science.gov (United States)

Zhang, Qinhong; Sun, Zhongren; Yue, Jinhuan

2015-06-17

Pressure ulcers affect approximately 10% of patients in hospitals and the elderly are at highest risk. Several studies have suggested that massage therapy may help to prevent the development of pressure ulcers, but these results are inconsistent. To assess the evidence for the effects of massage compared with placebo, standard care or other interventions for prevention of pressure ulcers in at-risk populations.The review sought to answer the following questions:Does massage reduce the incidence of pressure ulcers of any grade?Is massage safe in the short- and long-term? If not, what are the adverse events associated with massage? We searched the Cochrane Wounds Group Specialised Register (8 January 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (2015, Issue 1), Ovid MEDLINE (1946 to 8 January 2015), Ovid MEDLINE (In-Process Other Non-Indexed Citations 8 January 2015), Ovid EMBASE (1974 to 8 January 2015), and EBSCO CINAHL (1982 to 8 January 2015). We did not apply date or language restrictions. We planned to include all randomised controlled trials (RCTs) and quasi-randomised controlled trials (Q-RCTs) that evaluated the effects of massage therapy for the prevention of pressure ulcers. Our primary outcome was the proportion of people developing a new pressure ulcer of any grade. Two review authors independently carried out trial selection. Disagreements were resolved by discussion. No studies (RCTs or Q-RCTs) met the inclusion criteria. Therefore, neither a meta-analysis nor a narrative description of studies was possible. There are currently no studies eligible for inclusion in this review. It is, therefore, unclear whether massage therapy can prevent pressure ulcers.

Potential of Jatropha multifida sap against traumatic ulcer

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Basri A. Gani

2015-09-01

Full Text Available Background: Traumatic ulcer is a lesion in oral mucosa as a result of physical and mechanical trauma, as well as changes in salivary pH. Jatropha multifida sap can act as antimicrobial, anti-inflammatory and re-epithelialization, and can also trigger the healing process of ulcers. Purpose: Research was aimed to determine the potential of Jatropha multifida sap against traumatic ulcer base on clinical and histopathological healing process. Method: This research was conducted laboratory experimental model, with rats (Rattus norvegicus as the subject as well as Jatropha multifida sap for ulcer healing. Those subjects were divided into four groups: two treatment groups administrated with pellet and Jatropha multifida sap, one group as the positive control group administrated with 0.1% triamcinolone acetonide, and one group as the negative control group administrated with 0.9% NaCl. Ulcer manipulation was used 30% H2O2, and evaluation of ulcer healing was used clinical and histopathological approach. Result: Clinically, the healing process of ulcers in the treatment group with Jatropha multifida sap was faster than that in the positive control group with 0.1% triamcinolone acetonide, indicated with the reduction of the ulcer size until the missing of the ulcers started from the third day to the seventh one (p≤0.05. Histopathologically inflammatory cells (lymphocytes, and plasma cells declined started from the third day, and the formation of collagen and re-epithelialization then occurred. On the seventh day, the epithelial cells thickened, and the inflammatory cells infiltrated. Statistically, those groups were significant (p≤0.05. Conclusion: Jatropha multifida sap has a significant potential to cure traumatic ulcers on oral mucosa clinically and histopathologically.

Mud Volcanoes of Trinidad as Astrobiological Analogs for Martian Environments

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Riad Hosein

2014-10-01

Full Text Available Eleven onshore mud volcanoes in the southern region of Trinidad have been studied as analog habitats for possible microbial life on Mars. The profiles of the 11 mud volcanoes are presented in terms of their physical, chemical, mineralogical, and soil properties. The mud volcanoes sampled all emitted methane gas consistently at 3% volume. The average pH for the mud volcanic soil was 7.98. The average Cation Exchange Capacity (CEC was found to be 2.16 kg/mol, and the average Percentage Water Content was 34.5%. Samples from three of the volcanoes, (i Digity; (ii Piparo and (iii Devil’s Woodyard were used to culture bacterial colonies under anaerobic conditions indicating possible presence of methanogenic microorganisms. The Trinidad mud volcanoes can serve as analogs for the Martian environment due to similar geological features found extensively on Mars in Acidalia Planitia and the Arabia Terra region.