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Sample records for voice onset times

  1. Voice Onset Time in Parkinson Disease

    Science.gov (United States)

    Fischer, Emily; Goberman, Alexander M.

    2010-01-01

    Research has found that speaking rate has an effect on voice onset time (VOT). Given that Parkinson disease (PD) affects speaking rate, the purpose of this study was to examine VOT with the effect of rate removed (VOT ratio), along with the traditional VOT measure, in individuals with PD. VOT and VOT ratio were examined in 9 individuals with PD…

  2. Voice Onset Time in Parkinson Disease

    Science.gov (United States)

    Fischer, Emily; Goberman, Alexander M.

    2010-01-01

    Research has found that speaking rate has an effect on voice onset time (VOT). Given that Parkinson disease (PD) affects speaking rate, the purpose of this study was to examine VOT with the effect of rate removed (VOT ratio), along with the traditional VOT measure, in individuals with PD. VOT and VOT ratio were examined in 9 individuals with PD…

  3. Measurement of Voice Onset Time in Maxillectomy Patients

    Directory of Open Access Journals (Sweden)

    Mariko Hattori

    2014-01-01

    Full Text Available Objective speech evaluation using acoustic measurement is needed for the proper rehabilitation of maxillectomy patients. For digital evaluation of consonants, measurement of voice onset time is one option. However, voice onset time has not been measured in maxillectomy patients as their consonant sound spectra exhibit unique characteristics that make the measurement of voice onset time challenging. In this study, we established criteria for measuring voice onset time in maxillectomy patients for objective speech evaluation. We examined voice onset time for /ka/ and /ta/ in 13 maxillectomy patients by calculating the number of valid measurements of voice onset time out of three trials for each syllable. Wilcoxon’s signed rank test showed that voice onset time measurements were more successful for /ka/ and /ta/ when a prosthesis was used (Z=−2.232, P=0.026 and Z=−2.401, P=0.016, resp. than when a prosthesis was not used. These results indicate a prosthesis affected voice onset measurement in these patients. Although more research in this area is needed, measurement of voice onset time has the potential to be used to evaluate consonant production in maxillectomy patients wearing a prosthesis.

  4. Visual Influences on Alignment to Voice Onset Time

    Science.gov (United States)

    Sanchez, Kauyumari; Miller, Rachel M.; Rosenblum, Lawrence D.

    2010-01-01

    Purpose: Speech shadowing experiments were conducted to test whether alignment (inadvertent imitation) to voice onset time (VOT) can be influenced by visual speech information. Method: Experiment 1 examined whether alignment would occur to auditory /pa/ syllables manipulated to have 3 different VOTs. Nineteen female participants were asked to…

  5. Voice Onset Time in Indian English-Accented Speech

    Science.gov (United States)

    Awan, Shaheen N.; Stine, Carolyn L

    2011-01-01

    The purpose of this study was to determine possible differences in voice onset time (VOT) between speakers of standard American English (AE) and Indian English (IE) in a continuous speech context. The participants were 20 AE speakers, who were native to the Northeastern Pennsylvania region, and 20 IE speakers from the Indian subcontinent who had…

  6. Voice Onset Time Production in Speakers with Alzheimer's Disease

    Science.gov (United States)

    Baker, Julie; Ryalls, Jack; Brice, Alejandro; Whiteside, Janet

    2007-01-01

    In the present study, voice onset time (VOT) measurements were compared between a group of individuals with moderate Alzheimer's disease (AD) and a group of healthy age- and gender-matched peers. Participants read a list of consonant-vowel-consonant (CVC) words, which included the six stop consonants. The VOT measurements were made from…

  7. Development of Voice Onset Time in Standard-Greek and Cypriot-Greek-Speaking Preschoolers

    Science.gov (United States)

    Okalidou, Areti; Petinou, Kakia; Theodorou, Eleni; Karasimou, Eleni

    2010-01-01

    The current investigation examined the development of voice onset time (VOT) in Standard-Greek (SG) and Cypriot-Greek (CG)-speaking children at age levels 2;0-2;5, 2;6-2;11, 3;0-3;5, and 3;6-4;0 years. SG presents with a two-way voicing contrast (voiced and voiceless unaspirated stops) whereas CG is a three-way contrast dialect containing…

  8. Global Foreign Accent and Voice Onset Time Among Japanese EFL Speakers.

    Science.gov (United States)

    Riney, Timothy J.; Takagi, Naoyuki

    1999-01-01

    Investigated the correlation between global foreign accent (GFA) and voice onset time (VOT). VOT values for /p/, /t/, and /k/ were measured at two times, separated by an interval of 42 months. Subjects were 11 Japanese speakers of English as a foreign language; 5 age-matched native speakers of English served as the control group. (Author/VWL)

  9. The effect of speakers' sex on voice onset time in Mandarin stops.

    Science.gov (United States)

    Li, Fangfang

    2013-02-01

    The goal of the present study is to examine the effect of speakers' gender on voice onset time in Mandarin speakers' stop productions. Word-initial lingual stops were elicited from 10 male and 10 female Mandarin speakers using a word-repetition task. The results revealed differentiated voice onset time (VOT) patterns between the two genders for all four lingual stops on raw VOT values. After factoring out speech rate variation, gender-related differences remained for voiced stops only with females' VOTs being shorter than males. The results, together with previous findings from other languages, suggest a sociolinguistic/stylistic account on the relation between gender and VOT that vary in a language-specific manner.

  10. The design of a microcomputer-controlled voice onset time analyzer.

    Science.gov (United States)

    Moeini, S M; Flege, J E; McCutcheon, M J

    1990-01-01

    In spoken syllables such as "ta," the interval between the release of the tongue constriction for the stop consonant /t/ and the onset of the vowel is called voice onset time, or VOT. Voice onset time is an important determinant of whether the initial consonant will be heard as a /t/(values of 60-90 ms) or as a /d/ (values of 0-30 ms). VOT information, immediately following a spoken syllable, can provide a speaker with feedback for modifying speech production. Such information can help the hearing-impaired learn to speak. It may also help people who learn English as a second language, since they often produce /b,d,g/ and /p,t,k/ with inappropriate VOT values. A prototype portable device measures VOT for initial voiced and voiceless stop consonants (e.g., "da" and "ta"). A dual-microphone method is used for acoustic measurement. A microphone in front of the mouth picks up the radiated acoustic signal; another over the larynx transduces vocal vibrations that mark the beginning of a vowel. Analog circuits process the transducer signals and provide gain and filtering. Filters were designed on the basis of the acoustic properties of stop consonants. The output from each analog circuit is fed to a comparator that compares the signal level with a fixed threshold voltage reference. A digital timer starts when the amplitude of the oral signal voltage exceeds a threshold and stops when the laryngeal signal voltage exceeds a threshold. VOT values obtained by the device were compared with those made from digital waveforms of words spoken by five talkers.(ABSTRACT TRUNCATED AT 250 WORDS)

  11. Sex differences in voice onset time: A developmental study of phonetic context effects in British English

    Science.gov (United States)

    Whiteside, Sandra P.; Henry, Luisa; Dobbin, Rachel

    2004-08-01

    Voice onset time (VOT) data for the plosives /p b t d k g/ in two vowel contexts (eye opena) for 5 groups of 46 boys and girls aged 5; 8 (5 years, 8 months) to 13;2 years were investigated to examine patterns of sex differences. Results indicated that there was some evidence of females displaying longer VOT values than the males. In addition, these were found to be most marked for the data of the 13;2-year olds. Furthermore, the sex differences in the VOT values displayed phonetic context effects. For example, the greatest sex differences were observed for the voiceless plosives, and within the context of the vowel /i/.

  12. On Voice-Onset Time as a Cue to Foreign Accent in Spanish: Native and Nonnative Perceptions

    Science.gov (United States)

    Schoonmaker-Gates, Elena

    2015-01-01

    Although previous research has documented the relationship between voice-onset time (VOT) and the production of foreign accent in English and Spanish, less is known about the role of this cue in perception. VOT refers to the aspiration that occurs between the release of a stop consonant and the beginning of the following segment. In Spanish and…

  13. The effect of vowel height on Voice Onset Time in stop consonants in CV sequences in spontaneous Danish

    DEFF Research Database (Denmark)

    Mortensen, Johannes; Tøndering, John

    2013-01-01

    Voice onset time has been reported to vary with the height of vowels following the stop consonant. This paper investigates the effects of vowel height on VOT in Danish CV sequences with stop consonants in Danish spontaneous speech. A significant effect of vowel height on VOT was found...

  14. Auditory discrimination of voice-onset time and its relationship with reading ability.

    Science.gov (United States)

    Arciuli, Joanne; Rankine, Tracey; Monaghan, Padraic

    2010-05-01

    The perception of voice-onset time (VOT) during dichotic listening provides unique insight regarding auditory discrimination processes and, as such, an opportunity to learn more about individual differences in reading ability. We analysed the responses elicited by four VOT conditions: short-long pairs (SL), where a syllable with a short VOT was presented to the left ear and a syllable with a long VOT was presented to the right ear, as well as long-short (LS), short-short (SS), and long-long (LL) pairs. Stimuli were presented in three attention conditions, where participants were instructed to attend to either the left or right ear, or received no instruction. By around 9.5 years of age children perform similarly to adults in terms of the size and relative magnitude of the right ear advantage (REA) elicited by each of the four VOT conditions. Overall, SL pairs elicited the largest REA and LS pairs elicited a left ear advantage (LEA), reflecting stimulus-driven bottom-up processes. However, children were less able to modulate their responses according to attention condition, reflecting a lack of top-down control. Effective direction of attention to one ear or the other was related to measures of reading accuracy and comprehension, indicating that reading skill is associated with top-down control of bottom-up perceptual processes.

  15. Effects of Age, Sex and Syllable Number on Voice Onset Time: Evidence from Children's Voiceless Aspirated Stops.

    Science.gov (United States)

    Yu, Vickie Y; De Nil, Luc F; Pang, Elizabeth W

    2015-06-01

    Voice onset time (VOT) is a temporal acoustic parameter that reflects motor speech coordination skills. This study investigated the patterns of age and sex differences across development of voice onset time in a group of 70 English-speaking children, ranging in age from 4.1 to 18.4 years, and 12 young adults. The effect of the number of syllables on VOT patterns was also examined. Speech samples were elicited by producing syllables /pa/ and /pataka/. Results supported previous findings showing that younger children produce longer VOT values with higher levels of variability. Markedly higher VOT values and increased variability were found for boys at ages between 8 and 11 years, confirming sex differences in VOT patterns and patterns of variability. In addition, all participants consistently produced shorter VOT with higher variability for multisyllables than monosyllables, indicating an effect of syllable number. Possible explanations for these findings and clinical implications are discussed.

  16. Effect of fundamental frequency at voice onset on vocal attack time.

    Science.gov (United States)

    Watson, Ben C; Baken, R J; Roark, Rick M; Reid, Stephanie; Ribeiro, Melissa; Tsai, Weilyn

    2013-05-01

    To examine vocal attack time (VAT) values associated with the production of low, mid, and high rates of vocal fold vibration in normal speakers. Sound pressure (SP) and electroglottographic (EGG) recordings were obtained for eight female and five male subjects while producing multiple tokens of the sustained vowels /ɑ/, /i/, and /u/ at comfortable loudness and at mid, low (-3 semitones), and high (+6 semitones) rates of vocal fold vibration. Generalized sinusoidal models of the SP and EGG signals were computed to compare rates of amplitude change. VAT was computed from the time lag of the cross-correlation function. Adjusted mean VAT for the high frequency condition was smaller than the adjusted mean VAT values for the low- and mid-frequency conditions. There was no significant difference between the mid and low frequency conditions. Findings reveal an association of the VAT measure with increases in vocal fold tension associated with the production of high rates of vocal fold vibration. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  17. Changes in spectral measures and voice-onset time with age: a cross-sectional and a longitudinal study.

    Science.gov (United States)

    Decoster, W; Debruyne, F

    1997-01-01

    In this study, we searched for changes in spectral features (during the sustained vowels [a] and [i]) and the voice onset time (VOT, of [pa] and [ka]) of the ageing voice. A longitudinal study (on 20 participants) and a cross-sectional study (on 265 participants) were conducted. The spectral parameters under consideration were: the difference in amplitude between the first and the second harmonic, the energy difference between the frequency band below 1 kHz and 2-4 kHz, and the energy difference between vowels [a] and [i]. A relatively stronger spectral level was found between 4 and 5 kHz in elderly men and women (60+) for [i] compared to young men and women (20-29 years). Significant differences in the longitudinal study were not identical to those of the cross-sectional study. After a time interval of 30 years, 20 men produced a relatively weaker 2- to 4-kHz part of the spectrum and the VOT became much longer. It was impossible to attribute the changes purely to the process of ageing. Situations and emotions also play an important role and contribute to the different findings of the two groups of participants under consideration.

  18. The stop voicing contrast in French sentences: contextual sensitivity of vowel duration, closure duration, voice onset time, stop release and closure voicing.

    Science.gov (United States)

    Abdelli-Beruh, Nassima B

    2004-01-01

    This study examined the manner in which French speakers used some acoustic correlates to produce the stop voicing distinction in French sentences when syllables containing syllable initial and -final stops were between vowels (/pa_a/) and between voiceless fricatives (/pas_s/). Data analyses revealed that /b, d, g/ were longer, were more frequently phonated, and were preceded by longer vowels than /p, t, k/ in three conditions: syllable-initial stops between vowels and between voiceless fricatives and syllable-final stops between vowels. When a voiceless fricative /s/ followed /b, d, g/, the voicing contrast was reduced as a result of complete regressive voicing assimilation, achieved by the concomitant devoicing of /b, d, g/ closures and the significant reduction in voicing-related differences in preceding vowel and closure durations. When /s/ preceded /b, d, g/, the voicing distinction was enhanced: significant voicing-related duration differences were accompanied by the complete assimilation of /s/ to [z]. Overall, findings suggest that in French sentences, voicing assimilation is strictly regressive and complete assimilation is achieved by the covariation of several acoustic correlates, which attests to the complementarity of the underlying articulatory gestures.

  19. Voice onset time and global foreign accent in mature Japanese-English bilinguals

    Science.gov (United States)

    Riney, Timothy J.

    2004-05-01

    Experiment 1 investigates to what degree the phonetic category established in childhood for an L1 sound may evolve gradually [Flege, Speech Learning Model (1995)]. VOT is assessed in two groups of five bilingual (English and Japanese) speakers, one L1 English and the other L1 Japanese, ages 35-60 with little or no L2 exposure before age 15, but working in the L2 regularly for 15-35 years in adulthood. Both groups read lists of English and Japanese words containing word initial /p/, /t/, and /k/; 880 tokens (10 speakers × 2 languages × 44 tokens per language) were examined. The findings for both groups were that (a) the L1 VOT values did not change much over time and (b) the L2 VOT values were halfway between the L1 and target language values. Experiment 2 investigates the relationship between individual VOT and accent. The ten speakers were asked to read five Japanese sentences, now digitized. Ten additional L1 Japanese participants will rate these sentences for accent in March 2004. The prediction is that the American speakers who have the most Japanese accents will also have VOT values that are closest to L1 Japanese values.

  20. Voice onset time and global foreign accent in mature Japanese-English bilinguals

    Science.gov (United States)

    Riney, Timothy J.

    2001-05-01

    Experiment 1 investigates to what degree the phonetic category established in childhood for an L1 sound may evolve gradually [Flege, Speech Learning Model (1995)]. VOT is assessed in two groups of five bilingual (English and Japanese) speakers, one L1 English and the other L1 Japanese, ages 35-60 with little or no L2 exposure before age 15, but working in the L2 regularly for 15-35 years in adulthood. Both groups read lists of English and Japanese words containing word initial /p/, /t/, and /k/; 880 tokens (10 speakers × 2 languages × 44 tokens per language) were examined. The findings for both groups were that (a) the L1 VOT values did not change much over time and (b) the L2 VOT values were halfway between the L1 and target language values. Experiment 2 investigates the relationship between individual VOT and accent. The ten speakers were asked to read five Japanese sentences, now digitized. Ten additional L1 Japanese participants will rate these sentences for accent in March 2004. The prediction is that the American speakers who have the most Japanese accents will also have VOT values that are closest to L1 Japanese values.

  1. Effects of age of learning on voice onset time: categorical perception of Swedish stops by near-native L2 speakers.

    Science.gov (United States)

    Stölten, Katrin; Abrahamsson, Niclas; Hyltenstam, Kenneth

    2014-12-01

    This study examined the effects of age of onset (AO) of L2 acquisition on the categorical perception of the voicing contrast in Swedish word-initial stops varying in voice onset time (VOT). Three voicing continua created on the basis of natural Swedish word pairs with /p-b/, /t-d/, /k-/ in initial position were presented to 41 Spanish early (AO 12) near-native speakers of L2 Swedish. Fifteen native speakers of Swedish served as controls. Categorizations were influenced by AO and listener status as L1/L2 speaker, in that the late learners deviated the most from native-speaker perception. In addition, only a small minority of the late learners perceived the voicing contrast in a way comparable to native-speaker categorization, while most early L2 learners demonstrated nativelike categorization patterns. However, when the results were combined with the L2 learners' production of Swedish voiceless stops (Stölten, 2005; Stölten, Abrahamsson & Hyltenstam, in press), nativelike production and perception was never found among the late learners, while a majority of the early learners still exhibited nativelike production and perception. It is concluded that, despite their being perceived as mother-tongue speakers of Swedish by native listeners, the late learners do not, after detailed phonetic scrutiny, exhibit a fully nativelike command of Swedish VOT. Consequently, being near-native rather than nativelike speakers of their second language, these individuals do not constitute the evidence necessary to reject the hypothesis of one or several critical (or sensitive) periods for language acquisition.

  2. Mechanism of and threshold biomechanical conditions for falsetto voice onset.

    Directory of Open Access Journals (Sweden)

    Shinji Deguchi

    Full Text Available The sound source of a voice is produced by the self-excited oscillation of the vocal folds. In modal voice production, a drastic increase in transglottal pressure after vocal fold closure works as a driving force that develops self-excitation. Another type of vocal fold oscillation with less pronounced glottal closure observed in falsetto voice production has been accounted for by the mucosal wave theory. The classical theory assumes a quasi-steady flow, and the expected driving force onto the vocal folds under wavelike motion is derived from the Bernoulli effect. However, wavelike motion is not always observed during falsetto voice production. More importantly, the application of the quasi-steady assumption to a falsetto voice with a fundamental frequency of several hundred hertz is unsupported by experiments. These considerations suggested that the mechanism of falsetto voice onset may be essentially different from that explained by the mucosal wave theory. In this paper, an alternative mechanism is submitted that explains how self-excitation reminiscent of the falsetto voice could be produced independent of the glottal closure and wavelike motion. This new explanation is derived through analytical procedures by employing only general unsteady equations of motion for flow and solids. The analysis demonstrated that a convective acceleration of a flow induced by rapid wall movement functions as a negative damping force, leading to the self-excitation of the vocal folds. The critical subglottal pressure and volume flow are expressed as functions of vocal fold biomechanical properties, geometry, and voice fundamental frequency. The analytically derived conditions are qualitatively and quantitatively reasonable in view of reported measurement data of the thresholds required for falsetto voice onset. Understanding of the voice onset mechanism and the explicit mathematical descriptions of thresholds would be beneficial for the diagnosis and treatment

  3. SILENT VOICES OF TIME

    African Journals Online (AJOL)

    NATIONAL MUSEUM OF MILITARY HISTORY. BY DR S MONICKl* .... The figure of the Greek goddess of Nike surmounts the .... and armed might, that contemporary observers became ... dance with the political facts of their times. Wilhelm II ...

  4. Onset and Maturation of Fetal Heart Rate Response to the Mother's Voice over Late Gestation

    Science.gov (United States)

    Kisilevsky, Barbara S.; Hains, Sylvia M. J.

    2011-01-01

    Background: Term fetuses discriminate their mother's voice from a female stranger's, suggesting recognition/learning of some property of her voice. Identification of the onset and maturation of the response would increase our understanding of the influence of environmental sounds on the development of sensory abilities and identify the period when…

  5. The impact of vocal hyperfunction on relative fundamental frequency during voicing offset and onset.

    Science.gov (United States)

    Stepp, Cara E; Hillman, Robert E; Heaton, James T

    2010-10-01

    This study tested the hypothesis that individuals with vocal hyperfunction would show decreases in relative fundamental frequency (RFF) surrounding a voiceless consonant. This retrospective study of 2 clinical databases used speech samples from 15 control participants and women with hyperfunction-related voice disorders: 82 prior to treatment (muscle tension dysphonia, n=22; vocal fold nodules, n=30; vocal fold polyps, N=30) and 18 before and after surgical removal of vocal fold nodules or polyps. Acoustic samples were analyzed with respect to the RFF at the offset and onset of voicing surrounding a voiceless consonant. Individuals with vocal hyperfunction in a large clinical sample showed significant lowering of offset and onset RFF compared with controls. Voicing offset and onset RFFs were not significantly changed by the removal of vocal fold lesions in the surgical group. Altered offset and onset RFF in patients with hyperfunction-related voice disorders can be interpreted as a by-product of heightened levels of laryngeal muscle tension. Measurement of RFF during voice offset and onset has potential for use as a simple, noninvasive measure of vocal hyperfunction.

  6. DSP Based System for Real time Voice Synthesis Applications Development

    CERN Document Server

    Arsinte, Radu; Miron, Costin

    2008-01-01

    This paper describes an experimental system designed for development of real time voice synthesis applications. The system is composed from a DSP coprocessor card, equipped with an TMS320C25 or TMS320C50 chip, voice acquisition module (ADDA2),host computer (IBM-PC compatible), software specific tools.

  7. Voice Initiation and Termination Times in Stuttering and Nonstuttering Children.

    Science.gov (United States)

    Cullinan, Walter L.; Springer, Mark T.

    1980-01-01

    The times needed to initiate and terminate voicing in response to series of short segments of auditory signal were studied for 20 stuttering and 20 nonstuttering children (ages for both groups 5 to 12). The effects of random reward and nonreward on the phonatory response times also were studied. (Author/PHR)

  8. Duração do onset vocálico da fala fluente de gagos Voice onset duration of stutterers' fluent speech

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    Cláudia Fassin Arcuri

    2010-01-01

    Full Text Available OBJETIVO: Comparar a duração da emissão da fala fluente de adultos com diferentes graus de gagueira em tarefa de repetição de frases. MÉTODOS: Seis adultos gagos, com grau de severidade variando de leve a severo, foram pareados com indivíduos sem nenhuma alteração de linguagem. O corpus foi composto pelas palavras "cavalo", "pipoca" e " tapete", inseridas em frases-veículo "Digo......baixinho". As frases foram emitidas pela pesquisadora e repetidas três vezes pelos indivíduos. A fala foi gravada diretamente em computador, tendo sido desconsideradas as emissões disfluentes. Posteriormente, foram realizadas as medidas de duração acústica das amostras, através do programa Praat 4.3. As frases foram divididas em segmentos delimitados por dois onsets vocálicos consecutivos. Os dados foram tabulados e analisados estatisticamente através do Teste-t e da ANOVA (Analysis of variance. RESULTADOS: Os gagos levaram mais tempo para emitir todas as unidades estudadas, com exceção da unidade [ib]. Na comparação entre os diferentes graus de severidade da gagueira, verificou-se que os gagos leves e moderados apresentam medidas de duração semelhantes e diferentes da dos gagos severos. CONCLUSÃO: Os parâmetros acústicos de duração delimitados pela medida dos onset vocálicos demonstraram que os gagos diferem dos não-gagos, além destas medidas diferenciarem os graus de severidade da gagueira.PURPOSE: To compare utterance duration of fluent speech of adults with different degrees of stuttering on a phrase repetition task. METHODS: Six adult stutterers, with severity degrees varying from mild to severe, were matched to individuals with no communication problems. The corpus was constituted by the words "horse", "popcorn" and "carpet" introduced into the vehicle-phrase "I say......quietly". Each phrase was uttered by the researcher and repeated aloud three times by the participants. The speech sample was recorded on a computer, and

  9. Real-Time Talking Avatar on the Internet Using Kinect and Voice Conversion

    Directory of Open Access Journals (Sweden)

    Takashi Nose

    2015-12-01

    Full Text Available We have more chances to communicate via the in-ternet. We often use text/video chat, but there are some problems, such as a lack of communication and anonymity. In this paper, we propose and implement a real-time talking avatar, where we can communicate with each other by synchronizing character’s voice and motion from ours while keeping anonymity by using a voice conversion technique. For the voice conversion, we improve accuracy of the voice conversion by specializing to the target character’s voice. Finally, we conduct subjective experiments and show the possibility of a new style of communication on the internet.

  10. Voice, (inter-)subjectivity, and real time recurrent interaction.

    Science.gov (United States)

    Cummins, Fred

    2014-01-01

    Received approaches to a unified phenomenon called "language" are firmly committed to a Cartesian view of distinct unobservable minds. Questioning this commitment leads us to recognize that the boundaries conventionally separating the linguistic from the non-linguistic can appear arbitrary, omitting much that is regularly present during vocal communication. The thesis is put forward that uttering, or voicing, is a much older phenomenon than the formal structures studied by the linguist, and that the voice has found elaborations and codifications in other domains too, such as in systems of ritual and rite. Voice, it is suggested, necessarily gives rise to a temporally bound subjectivity, whether it is in inner speech (Descartes' "cogito"), in conversation, or in the synchronized utterances of collective speech found in prayer, protest, and sports arenas world wide. The notion of a fleeting subjective pole tied to dynamically entwined participants who exert reciprocal influence upon each other in real time provides an insightful way to understand notions of common ground, or socially shared cognition. It suggests that the remarkable capacity to construct a shared world that is so characteristic of Homo sapiens may be grounded in this ability to become dynamically entangled as seen, e.g., in the centrality of joint attention in human interaction. Empirical evidence of dynamic entanglement in joint speaking is found in behavioral and neuroimaging studies. A convergent theoretical vocabulary is now available in the concept of participatory sense-making, leading to the development of a rich scientific agenda liberated from a stifling metaphysics that obscures, rather than illuminates, the means by which we come to inhabit a shared world.

  11. Voice, (Inter-Subjectivity, and Real Time Recurrent Interaction

    Directory of Open Access Journals (Sweden)

    Fred eCummins

    2014-07-01

    Full Text Available Received approaches to a unified phenomenon called language are firmly committed to a Cartesian view of distinct unobservable minds. Questioning this commitment leads us to recognize that the boundaries conventionally separating the linguistic from the non-linguistic can appear arbitrary, omitting much that is regularly present during vocal communication. The thesis is put forward that uttering, or voicing, is a much older phenomenon than the formal structures studied by the linguist, and that the voice has found elaborations and codifications in other domains too, such as in systems of ritual and rite. Voice, it is suggested, necessarily gives rise to a temporally bound subjectivity, whether it is in inner speech (Descartes' cogito, in conversation, or in the synchronized utterances of collective speech found in prayer, protest and sports arenas world wide. The notion of a fleeting subjective pole tied to dynamically entwined participants who exert reciprocal influence upon each other in real time provides an insightful way to understand notions of common ground, or socially shared cognition. It suggests that the remarkable capacity to construct a shared world that is so characteristic of Homo sapiens may be grounded in this ability to become dynamically entangled as seen, e.g., in the centrality of joint attention in human interaction. Empirical evidence of dynamic entanglement in joint speaking is found in behavioral and neuroimaging studies. A convergent theoretical vocabulary is now available in the concept of participatory sense-making, leading to the development of a rich scientific agenda liberated from a stifling metaphysics that obscures, rather than illuminates, the means by which we come to inhabit a shared world.

  12. The Impact of Vocal Hyperfunction on Relative Fundamental Frequency during Voicing Offset and Onset

    Science.gov (United States)

    Stepp, Cara E.; Hillman, Robert E.; Heaton, James T.

    2010-01-01

    Purpose: This study tested the hypothesis that individuals with vocal hyperfunction would show decreases in relative fundamental frequency (RFF) surrounding a voiceless consonant. Method: This retrospective study of 2 clinical databases used speech samples from 15 control participants and women with hyperfunction-related voice disorders: 82 prior…

  13. The Relationship between Perception of Vocal Effort and Relative Fundamental Frequency during Voicing Offset and Onset

    Science.gov (United States)

    Stepp, Cara E.; Sawin, Devon E.; Eadie, Tanya L.

    2012-01-01

    Purpose: In this study, the authors aimed to determine the relationship between relative fundamental frequency (RFF) and listener perception of vocal effort in individuals with varying degrees of vocal hyperfunction. Method: Thirty women diagnosed with voice disorders commonly associated with vocal hyperfunction and 10 healthy women provided…

  14. Response time effects of alerting tone and semantic context for synthesized voice cockpit warnings

    Science.gov (United States)

    Simpson, C. A.; Williams, D. H.

    1980-01-01

    Some handbooks and human factors design guides have recommended that a voice warning should be preceded by a tone to attract attention to the warning. As far as can be determined from a search of the literature, no experimental evidence supporting this exists. A fixed-base simulator flown by airline pilots was used to test the hypothesis that the total 'system-time' to respond to a synthesized voice cockpit warning would be longer when the message was preceded by a tone because the voice itself was expected to perform both the alerting and the information transfer functions. The simulation included realistic ATC radio voice communications, synthesized engine noise, cockpit conversation, and realistic flight routes. The effect of a tone before a voice warning was to lengthen response time; that is, responses were slower with an alerting tone. Lengthening the voice warning with another work, however, did not increase response time.

  15. SAPS onset timing during substorms and the westward traveling surge

    Science.gov (United States)

    Mishin, Evgeny, V.

    2016-07-01

    We present multispacecraft observations in the magnetosphere and conjugate ionosphere of the onset time of subauroral polarization streams (SAPS) and tens of keV ring current injections on the duskside in three individual substorms. This is probably the first unequivocal determination of the substorm SAPS onset timing. The time lag between the SAPS and substorm onsets is much shorter than the gradient-curvature drift time of ˜10 keV ions in the plasmasphere. It seemingly depends on the propagation time of substorm-injected plasma from the dipolarization onset region to the plasmasphere, as well as on the SAPS position. These observations suggest that fast onset SAPS and ring current injections are causally related to the two-loop system of the westward traveling surge.

  16. Solar wind control of the local time of substorm onset

    Science.gov (United States)

    Grocott, Adrian; Case, Nathan; Laundal, Karl; Laurens, Hannah; Milan, Steve

    2017-04-01

    We use solar wind and interplanetary magnetic field data, along with satellite global auroral imagery, to investigate what controls the magnetic local time (MLT) of substorm onset. We find that substorm onsets occur over a wide range of MLTs (18 - 4 hrs), with a typical MLT (mode) of 23 hrs. In agreement with previous studies, IMF BY , acts to move the onset to an earlier/later local time in the northern hemisphere and a later/earlier local time in the southern hemisphere, depending on the sign of BY , consistent with a twist of the conjugate magnetic field line. This effect explains a small fraction of the observed MLT variation (˜ 1 hr), but cannot account for the tendency of onset to be often displaced to earlier ( 23 hrs) MLTs in both hemispheres. We also inspect the relationship between solar wind V Y and onset MLT, which also has a small, but measurable effect on the local time of substorm onset. This effect acts in the same sense in the northern and southern hemispheres, moving onset to earlier times for positive V Y and later times for negative V Y . We find that a function relating both BY and V Y to onset MLT produces a better fit than a function based on either parameter alone.

  17. Voice Recognition Algorithms using Mel Frequency Cepstral Coefficient (MFCC) and Dynamic Time Warping (DTW) Techniques

    CERN Document Server

    Muda, Lindasalwa; Elamvazuthi, I

    2010-01-01

    Digital processing of speech signal and voice recognition algorithm is very important for fast and accurate automatic voice recognition technology. The voice is a signal of infinite information. A direct analysis and synthesizing the complex voice signal is due to too much information contained in the signal. Therefore the digital signal processes such as Feature Extraction and Feature Matching are introduced to represent the voice signal. Several methods such as Liner Predictive Predictive Coding (LPC), Hidden Markov Model (HMM), Artificial Neural Network (ANN) and etc are evaluated with a view to identify a straight forward and effective method for voice signal. The extraction and matching process is implemented right after the Pre Processing or filtering signal is performed. The non-parametric method for modelling the human auditory perception system, Mel Frequency Cepstral Coefficients (MFCCs) are utilize as extraction techniques. The non linear sequence alignment known as Dynamic Time Warping (DTW) intro...

  18. A note on voice timing and the evolution of connected speech.

    Science.gov (United States)

    Fourcin, Adrian

    2010-07-01

    Voice is a dominant component of everyday speech in all languages. The possibility is examined that its use may have evolved so that its timing in connected speech is ideal from the point of view of information theory-with voicing taking up 50% of the total speaking time. Initial measurements have been made of voice timing proportions using Laryngograph (EGG) signals as the basis of timing analyses. The results of these analyses for data from two groups of speakers are reported: single native speakers of each of 8 different languages; and 56 speakers of British English. The average 51% and 52% voice timing proportions that were found closely approximate the ideal of 50%. Implications of this finding for voice evolution are briefly discussed.

  19. Extracting the Neural Representation of Tone Onsets for Separate Voices of Ensemble Music Using Multivariate EEG Analysis

    DEFF Research Database (Denmark)

    Sturm, Irene; Treder, Matthias S.; Miklody, Daniel

    2015-01-01

    When listening to ensemble music even non-musicians can follow single instruments effortlessly. Electrophysiological indices for neural sensory encoding of separate streams have been described using oddball paradigms which utilize brain reactions to sound events that deviate from a repeating...... standard pattern. Obviously, these paradigms put constraints on the compositional complexity of the musical stimulus. Here, we apply a regression-based method of multivariate EEG analysis in order to reveal the neural encoding of separate voices of naturalistic ensemble music that is based on cortical...... responses to tone onsets, such as N1/P2 ERP components. Music clips (resembling minimalistic electro-pop) were presented to 11 subjects, either in an ensemble version (drums, bass, keyboard) or in the corresponding three solo versions. For each instrument we train a spatio-temporal regression filter...

  20. An Improved Time Domain Pitch Detection Algorithm for Pathological Voice

    Directory of Open Access Journals (Sweden)

    Mohd R. Jamaludin

    2012-01-01

    Full Text Available Problem statement: The present study proposes a new pitch detection algorithm which could potentially be used to detect pitch for disordered or pathological voices. One of the parameters required for dysphonia diagnosis is pitch and this prompted the development of a new and reliable pitch detection algorithm capable of accurately detect pitch in disordered voices. Approach: The proposed method applies a technique where the frame size of the half wave rectified autocorrelation is adjusted to a smaller frame after two potential pitch candidates are identified within the preliminary frame. Results: The method is compared to PRAATs standard autocorrelation and the result shows a significant improvement in detecting pitch for pathological voices. Conclusion: The proposed method is more reliable way to detect pitch, either in low or high pitched voice without adjusting the window size, fixing the pitch candidate search range and predefining threshold like most of the standard autocorrelation do.

  1. Phonetically Governed Voicing Onset and Offset in Preschool Children Who Stutter

    Science.gov (United States)

    Arenas, Richard M.; Zebrowski, Patricia M.; Moon, Jerald B.

    2012-01-01

    Phonetically governed changes in the fundamental frequency (F[subscript 0]) of vowels that immediately precede and follow voiceless stop plosives have been found to follow consistent patterns in adults and children as young as four years of age. In the present study, F[subscript 0] onset and offset patterns in 14 children who stutter (CWS) and 14…

  2. The pattern of cognitive symptoms predicts time to dementia onset.

    NARCIS (Netherlands)

    Sacuiu, S.; Gustafson, D.; Johansson, B.; Thorvaldsson, V.; Berg, S.; Sjogren, J.M.C.; Guo, X.; Ostling, S.; Skoog, I.

    2009-01-01

    BACKGROUND: Few studies have examined whether cognitive symptom patterns differ by age and length of time before dementia onset. Our objective was to investigate whether different patterns of cognitive symptoms at ages 70, 75, and 79 years predict short-term (< or =5 years) and long-term (>5 y

  3. The pattern of cognitive symptoms predicts time to dementia onset.

    NARCIS (Netherlands)

    Sacuiu, S.; Gustafson, D.; Johansson, B.; Thorvaldsson, V.; Berg, S.; Sjogren, J.M.C.; Guo, X.; Ostling, S.; Skoog, I.

    2009-01-01

    BACKGROUND: Few studies have examined whether cognitive symptom patterns differ by age and length of time before dementia onset. Our objective was to investigate whether different patterns of cognitive symptoms at ages 70, 75, and 79 years predict short-term (< or =5 years) and long-term (>5 y

  4. The pattern of cognitive symptoms predicts time to dementia onset.

    NARCIS (Netherlands)

    Sacuiu, S.; Gustafson, D.; Johansson, B.; Thorvaldsson, V.; Berg, S.; Sjogren, J.M.C.; Guo, X.; Ostling, S.; Skoog, I.

    2009-01-01

    BACKGROUND: Few studies have examined whether cognitive symptom patterns differ by age and length of time before dementia onset. Our objective was to investigate whether different patterns of cognitive symptoms at ages 70, 75, and 79 years predict short-term (< or =5 years) and long-term (>5

  5. Glottal closure instant and voice source analysis using time-scale lines of maximum amplitude

    Indian Academy of Sciences (India)

    Christophe D’Alessandro; Nicolas Sturmel

    2011-10-01

    1Time-scale representation of voiced speech is applied to voice quality analysis, by introducing the Line of Maximum Amplitude (LoMA) method. This representation takes advantage of the tree patterns observed for voiced speech periods in the time-scale domain. For each period, the optimal LoMA is computed by linking amplitude maxima at each scale of a wavelet transform, using a dynamic programming algorithm. A time-scale analysis of the linear acoustic model of speech production shows several interesting properties. The LoMA points to the glottal closure instants. The LoMA phase delay is linked to the voice open quotient. The cumulated amplitude along the LoMA is related to voicing amplitude. The LoMA spectral centre of gravity is an indication of voice spectral tilt. Following these theoretical considerations, experimental results are reported. Comparative evaluation demonstrates that the LoMA is an effective method for the detection of Glottal Closure Instants (GCI). The effectiveness of LoMA analysis for open quotient, amplitude and spectral tilt estimations is also discussed with the help of some examples.

  6. Time to diagnosis in young-onset dementia as compared with late-onset dementia

    NARCIS (Netherlands)

    Vliet, D. van; Vugt, M.E. de; Bakker, C.; Pijnenburg, Y.A.; Vernooij-Dassen, M.J.F.J.; Koopmans, R.T.C.M.; Verhey, F.R.J.

    2013-01-01

    BACKGROUND: The extent to which specific factors influence diagnostic delays in dementia is unclear. Therefore, the aim of the present study was to compare duration from symptom onset to diagnosis for young-onset dementia (YOD) and late-onset dementia (LOD) and to assess the effect of age at onset,

  7. Classifying human voices by using hybrid SFX time-series preprocessing and ensemble feature selection.

    Science.gov (United States)

    Fong, Simon; Lan, Kun; Wong, Raymond

    2013-01-01

    Voice biometrics is one kind of physiological characteristics whose voice is different for each individual person. Due to this uniqueness, voice classification has found useful applications in classifying speakers' gender, mother tongue or ethnicity (accent), emotion states, identity verification, verbal command control, and so forth. In this paper, we adopt a new preprocessing method named Statistical Feature Extraction (SFX) for extracting important features in training a classification model, based on piecewise transformation treating an audio waveform as a time-series. Using SFX we can faithfully remodel statistical characteristics of the time-series; together with spectral analysis, a substantial amount of features are extracted in combination. An ensemble is utilized in selecting only the influential features to be used in classification model induction. We focus on the comparison of effects of various popular data mining algorithms on multiple datasets. Our experiment consists of classification tests over four typical categories of human voice data, namely, Female and Male, Emotional Speech, Speaker Identification, and Language Recognition. The experiments yield encouraging results supporting the fact that heuristically choosing significant features from both time and frequency domains indeed produces better performance in voice classification than traditional signal processing techniques alone, like wavelets and LPC-to-CC.

  8. Perception of initial obstruent voicing is influenced by gestural organization

    Science.gov (United States)

    Best, Catherine T.; Hallé, Pierre A.

    2009-01-01

    Cross-language differences in phonetic settings for phonological contrasts of stop voicing have posed a challenge for attempts to relate specific phonological features to specific phonetic details. We probe the phonetic-phonological relationship for voicing contrasts more broadly, analyzing in particular their relevance to nonnative speech perception, from two theoretical perspectives: feature geometry and articulatory phonology. Because these perspectives differ in assumptions about temporal/phasing relationships among features/gestures within syllable onsets, we undertook a cross-language investigation on perception of obstruent (stop, fricative) voicing contrasts in three nonnative onsets that use a common set of features/gestures but with differing time-coupling. Listeners of English and French, which differ in their phonetic settings for word-initial stop voicing distinctions, were tested on perception of three onset types, all nonnative to both English and French, that differ in how initial obstruent voicing is coordinated with a lateral feature/gesture and additional obstruent features/gestures. The targets, listed from least complex to most complex onsets, were: a lateral fricative voicing distinction (Zulu /ɬ/-ɮ/), a laterally-released affricate voicing distinction (Tlingit /tɬ/-/dɮ/), and a coronal stop voicing distinction in stop+/l/ clusters (Hebrew /tl/-/dl/). English and French listeners' performance reflected the differences in their native languages' stop voicing distinctions, compatible with prior perceptual studies on singleton consonant onsets. However, both groups' abilities to perceive voicing as a separable parameter also varied systematically with the structure of the target onsets, supporting the notion that the gestural organization of syllable onsets systematically affects perception of initial voicing distinctions. PMID:20228878

  9. Perception of initial obstruent voicing is influenced by gestural organization.

    Science.gov (United States)

    Best, Catherine T; Hallé, Pierre A

    2010-01-01

    Cross-language differences in phonetic settings for phonological contrasts of stop voicing have posed a challenge for attempts to relate specific phonological features to specific phonetic details. We probe the phonetic-phonological relationship for voicing contrasts more broadly, analyzing in particular their relevance to nonnative speech perception, from two theoretical perspectives: feature geometry and articulatory phonology. Because these perspectives differ in assumptions about temporal/phasing relationships among features/gestures within syllable onsets, we undertook a cross-language investigation on perception of obstruent (stop, fricative) voicing contrasts in three nonnative onsets that use a common set of features/gestures but with differing time-coupling. Listeners of English and French, which differ in their phonetic settings for word-initial stop voicing distinctions, were tested on perception of three onset types, all nonnative to both English and French, that differ in how initial obstruent voicing is coordinated with a lateral feature/gesture and additional obstruent features/gestures. The targets, listed from least complex to most complex onsets, were: a lateral fricative voicing distinction (Zulu /ɬ/-ɮ/), a laterally-released affricate voicing distinction (Tlingit /tɬ/-/dɮ/), and a coronal stop voicing distinction in stop+/l/ clusters (Hebrew /tl/-/dl/). English and French listeners' performance reflected the differences in their native languages' stop voicing distinctions, compatible with prior perceptual studies on singleton consonant onsets. However, both groups' abilities to perceive voicing as a separable parameter also varied systematically with the structure of the target onsets, supporting the notion that the gestural organization of syllable onsets systematically affects perception of initial voicing distinctions.

  10. BIOFILM DEVELOPMENT IN TIME ON A SILICONE VOICE PROSTHESIS - A CASE-STUDY

    NARCIS (Netherlands)

    NEU, TR; DEBOER, CE; VERKERKE, GJ; SCHUTTE, HK; RAKHORST, G; VANDERMEI, HC; BUSSCHER, HJ

    1994-01-01

    Voice prostheses from silicone elastomers become rapidly colonised by a mixed biofilm of bacteria and yeasts. In this study, microorganisms were isolated from biofilms on explanted prostheses after having been in place for various time intervals ranging from 1 to 67 d. The isolates were examined for

  11. Analytical Call Center Model with Voice Response Unit and Wrap-Up Time

    Directory of Open Access Journals (Sweden)

    Petr Hampl

    2015-01-01

    Full Text Available The last twenty years of computer integration significantly changed the process of service in a call center service systems. Basic building modules of classical call centers – a switching system and a group of humans agents – was extended with other special modules such as skills-based routing module, automatic call distribution module, interactive voice response module and others to minimize the customer waiting time and wage costs. A calling customer of a modern call center is served in the first stage by the interactive voice response module without any human interaction. If the customer requirements are not satisfied in the first stage, the service continues to the second stage realized by the group of human agents. The service time of second stage – the average handle time – is divided into a conversation time and wrap-up time. During the conversation time, the agent answers customer questions and collects its requirements and during the wrap-up time (administrative time the agent completes the task without any customer interaction. The analytical model presented in this contribution is solved under the condition of statistical equilibrium and takes into account the interactive voice response module service time, the conversation time and the wrap-up time.

  12. Effect of myopia onset time for macula choroidal thickness

    Directory of Open Access Journals (Sweden)

    Shi-Ming Wang

    2016-03-01

    Full Text Available AIM:To investigate the effect of onset time(Tfor macula choroidal thickness(CTin myopia patient. METHODS:A prospective cohort study was designed.One hundred and twenty-two myopia patients(244 eyes; 67 male and 55 female; aged 30~41 years, mean 35.1±4.6 years oldwho received preoperative examinations from March 2014 to April 2015 were recruited in this study. The patients were divided into three groups according to onset time(T:group A(T≤5a, group B(5aF=1.56,P>0.05,age(F=2.13,P>0.05,best corrected visual acuity(BCVA, F=1.41,P>0.05,corneal curvature(F=1.65,P>0.05and axial length(F=1.89,P>0.05among the three groups. The choroid in macular region was measured by enhanced depth imaging(EDIusing spectral-domain optical coherence tomography(SD-OCT. This study recorded the CT at subfoveal(SFCT, 1mm at temporal(T1mm, nasal(N1mm, superior(S1mmand inferior(I1mmto the fovea and 3mm temporal(T3mm, nasal(N3mm, superior(S3mmand inferior(I3mmto the fovea, respectively. The differences of CT at the same position among the three groups were analyzed.RESULTS:The mean SFCT for group A,B,C were 238.32±57.95μm, 230.58±67.21μm, 221.63±62.37μm respectively in this study. The CT was found no significant difference in different locations except N3mm(tA-B=4.34,P3mm(tB-C=7.61,P3mm(t=0.76,P>0.05between group A and C. Significant difference was found at N3mm(tA-B=4.31,t B-C=7.59,tA-C=12.18; PCONCLUSION:The choroidal thickness decreases as the myopia onset time is earlier, especially at nasal.

  13. A Joint Time-Frequency and Matrix Decomposition Feature Extraction Methodology for Pathological Voice Classification

    Directory of Open Access Journals (Sweden)

    Behnaz Ghoraani

    2009-01-01

    Full Text Available The number of people affected by speech problems is increasing as the modern world places increasing demands on the human voice via mobile telephones, voice recognition software, and interpersonal verbal communications. In this paper, we propose a novel methodology for automatic pattern classification of pathological voices. The main contribution of this paper is extraction of meaningful and unique features using Adaptive time-frequency distribution (TFD and nonnegative matrix factorization (NMF. We construct Adaptive TFD as an effective signal analysis domain to dynamically track the nonstationarity in the speech and utilize NMF as a matrix decomposition (MD technique to quantify the constructed TFD. The proposed method extracts meaningful and unique features from the joint TFD of the speech, and automatically identifies and measures the abnormality of the signal. Depending on the abnormality measure of each signal, we classify the signal into normal or pathological. The proposed method is applied on the Massachusetts Eye and Ear Infirmary (MEEI voice disorders database which consists of 161 pathological and 51 normal speakers, and an overall classification accuracy of 98.6% was achieved.

  14. Uplink Scheduling for Supporting Real Time Voice Traffic in IEEE 802.16 Backhaul Networks

    Institute of Scientific and Technical Information of China (English)

    Lizhong Dai; Dongmei Zhao

    2008-01-01

    In this paper we propose simple enhancements to the bandwidth (BW) request messages in IEEE 802.16 for supporting real-time packet voice traffic. Three different BW request formats are proposed, each requiring a different amount of latency information about the buffered packets at the SS. On this basis, packet scheduling schemes are proposed for the BS to make resource allocations for real-time traffic. Our results show that the proposed BW request and scheduling schemes achieve significantly lower packet loss probability than the standard IEEE 802.16 BW request with round robin scheduling.The results further show that there is an optimum point about how much delay information the SS should report to the BS in order to best utilize the uplink resources while the SS provides satisfactory real-time performance for the voice traffic.

  15. Onset of autumn shapes the timing of birth in Pyrenean chamois more than onset of spring.

    Science.gov (United States)

    Kourkgy, Charlotte; Garel, Mathieu; Appolinaire, Joël; Loison, Anne; Toïgo, Carole

    2016-03-01

    In seasonal environments, birth dates are a central component for a species' life history, with potential long-term fitness consequences. Yet our understanding of selective pressures of environmental changes on birth dates is limited in wild mammals due to the difficulty of data collection. In a context of rapid climate change, the question of a possible mismatch between plant phenology and birth phenology also remains unanswered for most species. We assessed whether and how the timing of birth in a mountain mammal (isard, also named Pyrenean chamois, Rupicapra pyrenaica pyrenaica) tracked changes in plant growing season, accounting for maternal traits, individual heterogeneity and population density. We not only focused on spring conditions but also assessed to what extent onset of autumn can be a driver of phenological biological events and compared the magnitude of the response to the magnitude of the environmental changes. We relied on a 22-year study based on intensively monitored marked individuals of known age. Births were highly synchronized (80% of kids born within 25 days) and highly repeatable (84%; between-female variation of 9.6 days, within-female variation of 4.2 days). Individual phenotypic plasticity allows females to respond rapidly to interannual changes in plant phenology but did not prevent the existence of a mismatch: a 10-day advance in the autumn or spring plant phenology led to 3.9 and 1.3 days advance in birth dates, respectively. Our findings suggest that plant phenology may act as a cue to induce important stages of the reproductive cycle (e.g. conception and gestation length), subsequently affecting parturition dates, and stressed the importance of focusing on long-term changes during spring for which females may show much lower adaptive potential than during autumn. These results also question the extent to which individual plasticity along with high heterogeneity among individuals will allow species to cope with demographic

  16. AN IMPROVED ALGORITHM OF GMM VOICE CONVERSION SYSTEM BASED ON CHANGING THE TIME-SCALE

    Institute of Scientific and Technical Information of China (English)

    Zhou Ying; Zhang Linghua

    2011-01-01

    This paper improves and presents an advanced method of the voice conversion system based on Gaussian Mixture Models (GMM) models by changing the time-scale of speech.The Speech Transformation and Representation using Adaptive Interpolation of weiGHTed spectrum (STRAIGHT) model is adopted to extract the spectrum features,and the GMM models are trained to generate the conversion function.The spectrum features of a source speech will be converted by the conversion function.The time-scale of speech is changed by extracting the converted features and adding to the spectrum.The conversion voice was evaluated by subjective and objective measurements.The results confirm that the transformed speech not only approximates the characteristics of the target speaker,but also more natural and more intelligible.

  17. Reaction time of voluntary modulations in voice F0 during sustained pitch vocalizations

    Science.gov (United States)

    Bauer, Jay J.; Larson, Charles R.; Eckstein, Kathryn C.

    2002-05-01

    In an attempt to more clearly understand the neural control of voice, a reaction time study was designed to investigate how rapidly normal subjects, i.e., nontrained singers, can voluntarily increase or decrease their voice fundamental frequency (F0) during sustained vocalizations when cued with a 1000-Hz auditory tone stimulus. Results revealed that overall reaction times (RTs) (F=21.9, df=2, 150, p=0.01) for upward F0 modulations occurred faster (range: 138-176 ms) than downward responses (range: 196-234 ms). In contrast to the reaction time findings, slightly higher peak velocities were observed for downward responses compared to upward responses. Shorter RTs observed for F0 elevation are therefore possibly related to central mechanisms involved in the planning of or execution of the direction in which F0 is to be modulated instead of muscle biomechanics. The fastest RTs obtained from the present study (138 ms) are slightly longer than the reflex latencies of the initial pitch-shift reflex response (100-130 ms) [Burnett, J. Acoust. Soc. Am. 103 (1998)], and provide additional evidence that subjects normally respond to inadvertent changes in their voice F0 with a fast, but limited reflex, followed by a secondary voluntary response. [Research supported by NIH Grant No. DC07264.

  18. Start/End Delays of Voiced and Unvoiced Speech Signals

    Energy Technology Data Exchange (ETDEWEB)

    Herrnstein, A

    1999-09-24

    Recent experiments using low power EM-radar like sensors (e.g, GEMs) have demonstrated a new method for measuring vocal fold activity and the onset times of voiced speech, as vocal fold contact begins to take place. Similarly the end time of a voiced speech segment can be measured. Secondly it appears that in most normal uses of American English speech, unvoiced-speech segments directly precede or directly follow voiced-speech segments. For many applications, it is useful to know typical duration times of these unvoiced speech segments. A corpus, assembled earlier of spoken ''Timit'' words, phrases, and sentences and recorded using simultaneously measured acoustic and EM-sensor glottal signals, from 16 male speakers, was used for this study. By inspecting the onset (or end) of unvoiced speech, using the acoustic signal, and the onset (or end) of voiced speech using the EM sensor signal, the average duration times for unvoiced segments preceding onset of vocalization were found to be 300ms, and for following segments, 500ms. An unvoiced speech period is then defined in time, first by using the onset of the EM-sensed glottal signal, as the onset-time marker for the voiced speech segment and end marker for the unvoiced segment. Then, by subtracting 300ms from the onset time mark of voicing, the unvoiced speech segment start time is found. Similarly, the times for a following unvoiced speech segment can be found. While data of this nature have proven to be useful for work in our laboratory, a great deal of additional work remains to validate such data for use with general populations of users. These procedures have been useful for applying optimal processing algorithms over time segments of unvoiced, voiced, and non-speech acoustic signals. For example, these data appear to be of use in speaker validation, in vocoding, and in denoising algorithms.

  19. ERP correlates of Motivating Voices: Quality of Motivation and Time-Course Matters.

    Science.gov (United States)

    Zougkou, Konstantina; Weinstein, Netta; Paulmann, Silke

    2017-05-19

    Here, we conducted the first study to explore how motivations expressed through speech are processed in real-time. Participants listened to sentences spoken in two types of well-studied motivational tones (autonomy-supportive and controlling), or a neutral tone of voice. To examine this, listeners were presented with sentences that either signaled motivations through prosody (tone of voice) and words simultaneously (e.g., "You absolutely have to do it my way" spoken in a controlling tone of voice), or lacked motivationally biasing words (e.g., "Why don't we meet again tomorrow" spoken in a motivational tone of voice). Event-related brain potentials (ERPs) in response to motivations conveyed through words and prosody showed that listeners rapidly distinguished between motivations and neutral forms of communication as shown in enhanced P2 amplitudes in response to motivational when compared to neutral speech. This early detection mechanism is argued to help determine the importance of incoming information. Once assessed, motivational language is continuously monitored and thoroughly evaluated. When compared to neutral speech, listening to controlling (but not autonomy-supportive) speech led to enhanced late potential ERP mean amplitudes, suggesting that listeners are particularly attuned to controlling messages. The importance of controlling motivation for listeners is mirrored in effects observed for motivations expressed through prosody only. Here, an early rapid appraisal, as reflected in enhanced P2 amplitudes, is only found for sentences spoken in controlling (but not autonomy-supportive) prosody. Once identified as sounding pressuring, the message seems to be preferentially processed, as shown by enhanced late potential amplitudes in response to controlling prosody. Taken together, results suggest that motivational and neutral language are differentially processed; further, the data suggest that listening to cues signaling pressure and control cannot be ignored

  20. Timing attention : Cuing target onset interval attenuates the attentional blink

    NARCIS (Netherlands)

    Martens, S; Johnson, A

    2005-01-01

    Three experiments tested whether the attentional blink (AB; a deficit in reporting the second of two targets when it occurs 200-500 msec after the first) can be attenuated by providing information about the target onset asynchrony (TOA) of the second target relative to the first. Blocking the TOA di

  1. Varieties of Voice-Hearing: Psychics and the Psychosis Continuum.

    Science.gov (United States)

    Powers, Albert R; Kelley, Megan S; Corlett, Philip R

    2017-01-01

    Hearing voices that are not present is a prominent symptom of serious mental illness. However, these experiences may be common in the non-help-seeking population, leading some to propose the existence of a continuum of psychosis from health to disease. Thus far, research on this continuum has focused on what is impaired in help-seeking groups. Here we focus on protective factors in non-help-seeking voice-hearers. We introduce a new study population: clairaudient psychics who receive daily auditory messages. We conducted phenomenological interviews with these subjects, as well as with patients diagnosed with a psychotic disorder who hear voices, people with a diagnosis of a psychotic disorder who do not hear voices, and matched control subjects (without voices or a diagnosis). We found the hallucinatory experiences of psychic voice-hearers to be very similar to those of patients who were diagnosed. We employed techniques from forensic psychiatry to conclude that the psychics were not malingering. Critically, we found that this sample of non-help-seeking voice hearers were able to control the onset and offset of their voices, that they were less distressed by their voice-hearing experiences and that, the first time they admitted to voice-hearing, the reception by others was much more likely to be positive. Patients had much more negative voice-hearing experiences, were more likely to receive a negative reaction when sharing their voices with others for the first time, and this was subsequently more disruptive to their social relationships. We predict that this sub-population of healthy voice-hearers may have much to teach us about the neurobiology, cognitive psychology and ultimately the treatment of voices that are distressing. © The Author 2016. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  2. Voice Onset Time in Consonant Cluster Errors: Can Phonetic Accommodation Differentiate Cognitive from Motor Errors?

    Science.gov (United States)

    Pouplier, Marianne; Marin, Stefania; Waltl, Susanne

    2014-01-01

    Purpose: Phonetic accommodation in speech errors has traditionally been used to identify the processing level at which an error has occurred. Recent studies have challenged the view that noncanonical productions may solely be due to phonetic, not phonological, processing irregularities, as previously assumed. The authors of the present study…

  3. Voice Onset Time in Consonant Cluster Errors: Can Phonetic Accommodation Differentiate Cognitive from Motor Errors?

    Science.gov (United States)

    Pouplier, Marianne; Marin, Stefania; Waltl, Susanne

    2014-01-01

    Purpose: Phonetic accommodation in speech errors has traditionally been used to identify the processing level at which an error has occurred. Recent studies have challenged the view that noncanonical productions may solely be due to phonetic, not phonological, processing irregularities, as previously assumed. The authors of the present study…

  4. A Variationist Account of Voice Onset Time among Bilingual West Indians in Panama

    Science.gov (United States)

    Lamy, Delano Sydney

    2012-01-01

    The present study is concerned with language contact between Creole English and Spanish spoken by bilingual West Indians who live in Panama City, Panama. The goal of this study is to examine the speech patterns of monolinguals of Creole English and Spanish and Spanish-Creole English bilinguals in the local communities of this region, by employing…

  5. Speech Perception and Production by Sequential Bilingual Children: A Longitudinal Study of Voice Onset Time Acquisition

    Science.gov (United States)

    McCarthy, Kathleen M.; Mahon, Merle; Rosen, Stuart; Evans, Bronwen G.

    2014-01-01

    The majority of bilingual speech research has focused on simultaneous bilinguals. Yet, in immigrant communities, children are often initially exposed to their family language (L1), before becoming gradually immersed in the host country's language (L2). This is typically referred to as sequential bilingualism. Using a longitudinal design, this…

  6. Voice development under training with and without the influence of real-time visually presented biofeedback.

    Science.gov (United States)

    Rossiter, D; Howard, D M; DeCosta, M

    1996-05-01

    This paper describes an investigation into the developmental nature of the voice under training with and without the influence of real-time visually presented biofeedback. Two subjects who had not previously experienced any form of vocal training took six singing lessons. One was taught conventionally, while the other was taught with the aid of a system known as Acoustic and Laryngeal Biofeedback Enhancement Real Time (ALBERT). Real-time biofeedback was presented based upon measures of (i) larynx closed quotient (CQ), (ii) spectral amplitude in the singer's formant frequency band relative to the spectral amplitude of the full band (ratio), and (iii) both parameters combined in a manner based on previously observed correlations between them. Results indicate generally increased sound pressure levels (SPL) of acoustic output and generally consistent increases in the level of CQ and ratio across consecutive lessons for both subjects.

  7. Design of real-time voice over internet protocol system under bandwidth network

    Science.gov (United States)

    Zhang, Li; Gong, Lina

    2017-04-01

    With the increasing bandwidth of the network and network convergence accelerating, VoIP means of communication across the network is becoming increasingly popular phenomenon. The real-time identification and analysis for VOIP flow over backbone network become the urgent needs and research hotspot of network operations management. Based on this, the paper proposes a VoIP business management system over backbone network. The system first filters VoIP data stream over backbone network and further resolves the call signaling information and media voice. The system can also be able to design appropriate rules to complete real-time reduction and presentation of specific categories of calls. Experimental results show that the system can parse and process real-time backbone of the VoIP call, and the results are presented accurately in the management interface, VoIP-based network traffic management and maintenance provide the necessary technical support.

  8. Timing of onset of CKD-related metabolic complications.

    Science.gov (United States)

    Moranne, Olivier; Froissart, Marc; Rossert, Jerome; Gauci, Cedric; Boffa, Jean-Jacques; Haymann, Jean Philippe; M'rad, Mona Ben; Jacquot, Christian; Houillier, Pascal; Stengel, Benedicte; Fouqueray, Bruno

    2009-01-01

    Chronic kidney disease (CKD) guidelines recommend evaluating patients with GFR acidosis from 2 to 39%, and hyperkalemia from 2 to 42%. Factors most strongly associated with metabolic complications, independent of mGFR, were younger age for acidosis and hyperphosphatemia, presence of diabetes for acidosis, diabetic kidney disease for anemia, and both male gender and the use of inhibitors of the renin-angiotensin system for hyperkalemia. mGFR thresholds for detecting complications with 90% sensitivity were 50, 44, 40, 39, and 37 ml/min per 1.73 m(2) for hyperparathyroidism, anemia, acidosis, hyperkalemia, and hyperphosphatemia, respectively. Analysis using estimated GFR produced similar results. In summary, this study describes the onset of CKD-related complications at different levels of GFR; anemia and hyperparathyroidism occur earlier than acidosis, hyperkalemia, and hyperphosphatemia.

  9. Phase onset time estimation at regional distances using the CUSUM algorithm

    Science.gov (United States)

    Der, Zoltan A.; Shumway, Robert H.

    1999-06-01

    A simple approach for the estimation of onset times of regional arrivals was tested. The method consists of the computation of the cumulative sum (CUSUM) of a test statistic, in this case, the absolute value of the trace amplitude, addition of a linear trend to the result and finding minima of the resulting function by various methods. The minima are located at the times where sudden increases in the trace amplitudes occur, i.e., at the phase onsets. The method requires frequency prefiltering in order to enhance the amplitude changes at the phase onsets. It was found that this algorithm performed comparably to a human analyst in finding onset times for Pn arrivals with varying S/ N ratios. Moreover, when applied to the rest of the seismogram, it was effective in finding the onset times of the rest of the regional arrivals as long as these were clearly visible. In the rest of the cases, where there are many poorly defined arrivals, an analyst would also have difficulties in uniquely defining onset times. The method also shares with the human analyst the tendency to pick the onset times late when an emergent arrival is buried in noise.

  10. Delay time for the onset of beam plasma discharge

    Science.gov (United States)

    Parish, J. L.; Denig, W. F.; Raitt, W. J.

    1987-01-01

    The interaction of a nonrelativistic electron beam with a neutral gas in a large chamber is considered, and the time interval before ignition of beam plasma discharge (BPD) is studied. A new theoretical expression for the time delay before BPD ignition is found as a function of the critical current necessary for BPD to be established. There are two parameters in the theoretical expression, and both are derived from two different experiments. These parameters are used to write the time evolution equation for plasma density as a function of time.

  11. Onset time and haemodynamic response after thiopental vs. propofol in the elderly: a randomized trial

    DEFF Research Database (Denmark)

    Sørensen, Martin Kryspin; Dolven, T L; Rasmussen, L S

    2011-01-01

    The induction dose of hypnotic agents should be reduced in the elderly, but it is not well studied whether thiopental or propofol should be preferred in this group of patients. The aim of this study was to compare onset time, hypnosis level and the haemodynamic response after thiopental vs....... propofol for induction of anaesthesia. Our primary hypothesis was that in the elderly, thiopental had a shorter onset time than propofol, defined as time to bispectral index (BIS)...

  12. Energy Dependence of SEP Electron and Proton Onset Times

    CERN Document Server

    Xie, Hong; Gopalswamy, Nat; Cyr, Orville St

    2016-01-01

    We study the large solar energetic particle (SEP) events that were detected by GOES in the $>$ 10 MeV energy channel during December 2006 to March 2014. We derive and compare solar particle release (SPR) times for the 0.25--10.4 MeV electrons and 10--100 MeV protons for the 28 SEP events. In the study, the electron SPR times are derived with the time-shifting analysis (TSA) and the proton SPR times are derived using both the TSA and the velocity dispersion analysis (VDA). Electron anisotropies are computed to evaluate the amount of scattering for the events under study. Our main results include: 1)near-relativistic electrons and high-energy protons are released at the same time within 8 min for most (16 of 23) SEP events. 2)There exists a good correlation between electron and proton acceleration, peak intensity and intensity time profiles. 3) The TSA SPR times for 90.5 MeV and 57.4 MeV protons have maximum errors of 6 min and 10 min compared to the proton VDA release times, respectively, while the maximum err...

  13. The Semantic Associative Ability in Preschoolers with Different Language Onset Time.

    Science.gov (United States)

    Di Giacomo, Dina; Ranieri, Jessica; Donatucci, Eliana; Caputi, Nicoletta; Passafiume, Domenico

    2016-01-01

    Aim of the study is to verify the semantic associative abilities in children with different language onset times: early, typical, and delayed talkers. The study was conducted on the sample of 74 preschool children who performed a Perceptual Associative Task, in order to evaluate the ability to link concepts by four associative strategies (function, part/whole, contiguity, and superordinate strategies). The results evidenced that the children with delayed language onset performed significantly better than the children with early language production. No difference was found between typical and delayed language groups. Our results showed that the children with early language onset presented weakness in the flexibility of elaboration of the concepts. The typical and delayed language onset groups overlapped performance in the associative abilities. The time of language onset appeared to be a predictive factor in the use of semantic associative strategies; the early talkers might present a slow pattern of conceptual processing, whereas the typical and late talkers may have protective factors.

  14. Voice Savers for Music Teachers

    Science.gov (United States)

    Cookman, Starr

    2012-01-01

    Music teachers are in a class all their own when it comes to voice use. These elite vocal athletes require stamina, strength, and flexibility from their voices day in, day out for hours at a time. Voice rehabilitation clinics and research show that music education ranks high among the professionals most commonly affected by voice problems.…

  15. Word Order and Voice Influence the Timing of Verb Planning in German Sentence Production

    Directory of Open Access Journals (Sweden)

    Sebastian Sauppe

    2017-09-01

    Full Text Available Theories of incremental sentence production make different assumptions about when speakers encode information about described events and when verbs are selected, accordingly. An eye tracking experiment on German testing the predictions from linear and hierarchical incrementality about the timing of event encoding and verb planning is reported. In the experiment, participants described depictions of two-participant events with sentences that differed in voice and word order. Verb-medial active sentences and actives and passives with sentence-final verbs were compared. Linear incrementality predicts that sentences with verbs placed early differ from verb-final sentences because verbs are assumed to only be planned shortly before they are articulated. By contrast, hierarchical incrementality assumes that speakers start planning with relational encoding of the event. A weak version of hierarchical incrementality assumes that only the action is encoded at the outset of formulation and selection of lexical verbs only occurs shortly before they are articulated, leading to the prediction of different fixation patterns for verb-medial and verb-final sentences. A strong version of hierarchical incrementality predicts no differences between verb-medial and verb-final sentences because it assumes that verbs are always lexically selected early in the formulation process. Based on growth curve analyses of fixations to agent and patient characters in the described pictures, and the influence of character humanness and the lack of an influence of the visual salience of characters on speakers' choice of active or passive voice, the current results suggest that while verb planning does not necessarily occur early during formulation, speakers of German always create an event representation early.

  16. Enhancement of the automatic onset time picking via wavelet thresholding

    Science.gov (United States)

    Gaci, Said

    2013-04-01

    Since arrival time-picking is a critical step in the analysis of geophysical data, many time picking algorithms have been developed. Nowadays, the ''short-time-average through long-time-average trigger'' (STA/LTA) in different forms are the most commonly used. This study aims at improving this algorithm in the presence of high amplitude noise. The suggested method consists of denoising the seismic trace using the discrete wavelet transform. Therefore, the STA/LTA curve obtained from the denoised trace displays a faster build up at the position of the wave arrival, and the picking error is reduced. The application of this technique is first demonstrated on synthetic seismic traces with varying noise levels, then extended to uphole seismic traces recorded in the Algerian Sahara. The results show that the picked first arrivals are more accurate than those yielded by the standard STA/LTA algorithm and this method can tolerate high noise levels. Keywords: picking, first arrival, seismic wave, wavelet thresholding.

  17. A double hit model for the distribution of time to AIDS onset

    Science.gov (United States)

    Chillale, Nagaraja Rao

    2013-09-01

    Incubation time is a key epidemiologic descriptor of an infectious disease. In the case of HIV infection this is a random variable and is probably the longest one. The probability distribution of incubation time is the major determinant of the relation between the incidences of HIV infection and its manifestation to Aids. This is also one of the key factors used for accurate estimation of AIDS incidence in a region. The present article i) briefly reviews the work done, points out uncertainties in estimation of AIDS onset time and stresses the need for its precise estimation, ii) highlights some of the modelling features of onset distribution including immune failure mechanism, and iii) proposes a 'Double Hit' model for the distribution of time to AIDS onset in the cases of (a) independent and (b) dependent time variables of the two markers and examined the applicability of a few standard probability models.

  18. Factors associated with onset timing, symptoms, and severity of depression identified in the postpartum period.

    Science.gov (United States)

    Fisher, Sheehan D; Wisner, Katherine L; Clark, Crystal T; Sit, Dorothy K; Luther, James F; Wisniewski, Stephen

    2016-10-01

    Unipolar and bipolar depression identified in the postpartum period have a heterogeneous etiology. The objectives of this study are to examine the risk factors that distinguish the timing of onset for unipolar and bipolar depression and the associations between depression onset by diagnosis, and general and atypical depressive symptoms. Symptoms of depression were assessed at 4- to 6-weeks postpartum by the Structured Interview Guide for the Hamilton Depression Rating Scale-Atypical Depression Symptoms in an obstetrical sample of 727 women. Data were analyzed using ANOVA, Chi-square, and linear regression. Mothers with postpartum onset of depression were more likely to be older, Caucasian, educated, married/cohabitating, have one or no previous child, and have private insurance in contrast to mothers with pre-pregnancy and prenatal onset of depression. Mothers with bipolar depression were more likely to have a pre-pregnancy onset. Three general and two atypical depressive symptoms distinguished pre-pregnancy, during pregnancy, and postpartum depression onset, and the presence of agitation distinguished between unipolar and bipolar depression. The sample was urban, which may not be generalizable to other populations. The study was cross-sectional, which excludes potential late onset of depression (after 4-6 weeks) in the first postpartum year. A collective set of factors predicted the onset of depression identified in the postpartum for mothers distinguished by episodes of unipolar versus bipolar depression, which can inform clinical interventions. Future research on the onset of major depressive episodes could inform prophylactic and early psychiatric interventions. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Pubertal Onset in Boys and Girls Is Influenced by Pubertal Timing of Both Parents

    DEFF Research Database (Denmark)

    Wohlfahrt-Veje, Christine; Mouritsen, Annette; Hagen, Casper P

    2016-01-01

    CONTEXT: Epidemiological evidence on maternal and paternal heritability of the wide normal variation within pubertal timing is sparse. OBJECTIVE: We aimed to estimate the impact of parental pubertal timing on the onset of puberty in boys and girls. DESIGN: Annual pubertal examinations of healthy...... children in a longitudinal cohort study. Information on parental timing of puberty (earlier, comparable to, or later compared to peers) and menarche age was retrieved from questionnaires. PARTICIPANTS: A total of 672 girls and 846 boys. MAIN OUTCOME MEASURES: Age at onset of pubic hair (PH2+), breasts (B2......+), and menarche in girls; and PH2+, genital stage (G2+), and testis >3 mL with orchidometer (Tvol3+) in boys. RESULTS: In boys, pubertal onset was significantly associated with pubertal timing of both parents. PH2+ and Tvol3+ were earlier: -11.8 months (95% confidence interval, -16.8, -6.8)/-8.9 (-12.8, -4...

  20. Is CT-based perfusion and collateral imaging sensitive to time since stroke onset?

    Directory of Open Access Journals (Sweden)

    Smriti eAgarwal

    2015-04-01

    Full Text Available Abstract PurposeCT-based perfusion and collateral imaging is increasingly used in the assessment of patients with acute stroke. Time of stroke onset is a critical factor in determining eligibility for and benefit from thrombolysis. Animal studies predict that the volume of ischemic penumbra decreases with time. Here we evaluate if CT is able to detect a relationship between perfusion or collateral status, as assessed by CT and time since stroke onset.Materials and MethodsWe studied fifty-three consecutive patients with proximal vessel occlusions, mean (SD age of 71.3 (14.9 years at a mean (SD of 125.2 (55.3 minutes from onset, using whole-brain CT perfusion (CTp imaging. Penumbra was defined using voxel-based thresholds for cerebral blood flow (CBF and mean transit time (MTT; core was defined by cerebral blood volume (CBV. Normalized penumbra fraction was calculated as Penumbra volume /(Penumbra volume +Core volume for both CBF and MTT (PenCBF and PenMTT, respectively. Collaterals were assessed on CT angiography (CTA. CTp ASPECTS score was applied visually, lower scores indicating larger lesions. ASPECTS ratios were calculated corresponding to penumbra fractions.ResultsBoth PenCBF and PenMTT showed decremental trends with increasing time since onset (Kendall’s tau-b=-0.196, p=0.055, and -0.187, p=0.068, respectively. The CBF/CBV ASPECTS ratio, which showed a relationship to PenCBF (Kendall’s tau-b=0.190, p=0.070, decreased with increasing time since onset (Kendall’s tau-b=-0.265, p=0.006. Collateral response did not relate to time (Kendall’s tau-b=-0.039, p=0.724.ConclusionEven within 4.5hrs since stroke onset, a decremental relationship between penumbra and time, but not between collateral status and time, may be detected using perfusion CT imaging. The trends that we demonstrate merit evaluation in larger datasets to confirm our results, which may have potential wider applications e.g. in the setting of strokes of unknown onset time.

  1. Time trends in age at onset of anorexia nervosa and bulimia nervosa.

    Science.gov (United States)

    Favaro, Angela; Caregaro, Lorenza; Tenconi, Elena; Bosello, Romina; Santonastaso, Paolo

    2009-12-01

    This study aims to explore the time trends in age at onset of anorexia nervosa and bulimia nervosa. The sample was composed of 1,666 anorexia nervosa subjects and 793 bulimia nervosa subjects (according to DSM-IV criteria) without previous anorexia nervosa consecutively referred to our outpatient unit in the period between 1985 and 2008. Time trends in illness onset were analyzed according to the year of birth of subjects. In both anorexia nervosa and bulimia nervosa, age at onset showed a significant decrease according to year of birth. A regression model showed a significant independent effect of socioeconomic status, age at menarche, and number of siblings in predicting age at onset lower than 16 years. Age at onset of anorexia nervosa and bulimia nervosa is decreasing in younger generations. The implications of our findings in terms of long-term outcome remain to be understood. Biologic and sociocultural factors explaining this phenomenon need to be explored in future studies. Copyright 2009 Physicians Postgraduate Press, Inc.

  2. The Effects of Language Experience and Speech Context on the Phonetic Accommodation of English-accented Spanish Voicing.

    Science.gov (United States)

    Llanos, Fernando; Francis, Alexander L

    2017-03-01

    Native speakers of Spanish with different amounts of experience with English classified stop-consonant voicing (/b/ versus /p/) across different speech accents: English-accented Spanish, native Spanish, and native English. While listeners with little experience with English classified target voicing with an English- or Spanish-like voice onset time (VOT) boundary, predicted by contextual VOT, listeners familiar with English relied on an English-like VOT boundary in an English-accented Spanish context even in the absence of clear contextual cues to English VOT. This indicates that Spanish listeners accommodated English-accented Spanish voicing differently depending on their degree of familiarization with the English norm.

  3. Fentanyl supplement expedites the onset time of sensory and motor blocking in interscalene lidocaine anesthesia

    Directory of Open Access Journals (Sweden)

    RS Moharari

    2010-12-01

    Full Text Available Background and the purpose of the study: Opioids are usually used in regional anesthesia, with or without local anesthetics to improve the regional block or postoperative pain control. Since no data are available on fentanyl's effect on the onset time of lidocaine interscalene anesthesia, the purpose of this study was to examine its effect on the onset time of sensory and motor blockade during interscalene anesthesia.  Methods: In a prospective, randomized, double-blind study, ninety patients scheduled for elective shoulder, arm and forearm surgeries under an  interscalene brachial plexus block .They were randomly allocated to receive either 30 ml of  1.5 % lidocaine with 1.5 ml of isotonic saline  (control group, n = 39 or 30 ml of 1.5%  lidocaine with 1.5 ml (75µg of  fentanyl (fentanyl group,n=41. Then the onset time of sensory and motor blockades of the shoulder, arm and forearm were evaluated every 60 sec. The onset time of the sensory and motor blockades was defined as the time between the last injection and the total abolition of the pinprick response and complete paralysis. The duration of sensory blocks were considered as the time interval between the administration of the local anesthetic and the first postoperative pain sensation. Results: Ten patients were excluded because of unsuccessful blockade or unbearable pain during the surgery. The onset time of the sensory block was significantly faster in the fentanyl group (186.54± 62.71sec compared with the control group (289.51± 81.22, P < 0.01. The onset times of the motor block up to complete paralysis in forearm flexion was significantly faster in the fentanyl group (260.61± 119.91sec than the control group (367.08± 162.43sec, P < 0.01 There was no difference in the duration of the sensory block between two groups. Conclusion: Results of the study showed that the combination of 75 µg fentanyl and 1.5% lidocaine solution accelerated the onset of sensory and motor

  4. Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time

    DEFF Research Database (Denmark)

    Gallwitz, B; Vaag, A; Falahati, A;

    2010-01-01

    AIM: To investigate the onset of treatment effects over time observed for liraglutide in combination with oral antidiabetic drugs (OADs). METHODS: This analysis included patients from three phase 3, 26-week, randomised, double-blind, parallel-group trials. Prior to randomisation, patients underwent...

  5. Time to onset of bisphosphonate-related osteonecrosis of the jaws

    DEFF Research Database (Denmark)

    Fung, Ppl; Bedogni, G; Bedogni, A

    2017-01-01

    OBJECTIVES: Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing duration of BP treatment, there are currently no reliable estimates of the ONJ time to onset (TTO). The objective of this study was to esti...

  6. Relationship of time to presentation after onset of upper GI bleeding with patient characteristics and outcomes

    DEFF Research Database (Denmark)

    Laine, Loren; Laursen, Stig B; Dalton, Harry R

    2017-01-01

    BACKGROUND & AIMS: We performed a prospective multi-national study of patients presenting to the emergency department with upper gastrointestinal bleeding (UGIB) and assessed the relationship of time to presentation after onset of UGIB symptoms with patient characteristics and outcomes. METHODS: ...

  7. The History and Timing of Depression Onset as Predictors of Young Adult Self-Esteem

    Science.gov (United States)

    Gayman, Mathew D.; Lloyd, Donald A.; Ueno, Koji

    2011-01-01

    Depression often emerges early in the lifecourse and is consistently shown to be associated with poor self-esteem. The 3 main objectives of the current study are to (1) evaluate the association between a history major depression and self-esteem in young adulthood, (2) assess the relationship between timing of depression onset and young adult…

  8. Quantitative t2 values predict time from symptom onset in acute stroke patients

    DEFF Research Database (Denmark)

    Siemonsen, Susanne; Mouridsen, Kim; Holst, Brigitte

    2009-01-01

    BACKGROUND AND PURPOSE: We hypothesize that in comparison to diffusion-weighted imaging, quantitative T2 values (qT2) are more directly related to water uptake in ischemic tissue, depending on time from symptom onset. We measured the increase of qT2 in the infarct core to quantify the correlation...

  9. Parametric time-to-onset (TTO) modelling of common ADRs in patients using antidiabetic drugs

    NARCIS (Netherlands)

    Scholl, Joep H.G.; Van De Ven, Peter M.; Van Puijenbroek, Eugène P.

    2015-01-01

    Background: Although the time-to-onset (TTO) is an important aspect in causality assessment of adverse drug reactions (ADRs), limited information about it is available in publicly available literature. Objectives: The aim of this study was to investigate whether the TTO of common ADRs of antidiabeti

  10. [Study of relationship between the onset time of sudden deafness and blood rheology].

    Science.gov (United States)

    Chen, Xiu-Mei; Zhang, Qing-Quan; Xie, Guang

    2007-03-01

    To investigate the correlation of the onset time of sudden deafness and blood rheology using a large-scale retrospective study. One hundred and ninety-eight patients of sudden deafness were examined with blood rheology and compared with 60 healthy people. Thirty patients were as subjects to study the circadian of blood rheology in order to search whether the blood rheology of morning was the highest. By divided 24 hours into twelve groups, each group contained two hours. Then the 198 patients were separated into twelve groups according to the time of onset. The blood rheology of each group was analyzed and compared with each other to observe which group was the highest. Most blood rheology index of the patients were higher than that of the healthy people. The onset time in most of the patients was during 4 am-8 am, but 45 patients during 4 am-6 am and 40 patients during 6 am-8 am. By analyzing and comparing the blood rheology of each group, the results showed that the blood rheology index in the group of 4 am-8 am was highest. And the blood rheology index of sudden deafness was highest in the morning. There was a close relation between blood rheology and sudden deafness. The peak time of onset was 4 am-8 am, and the patients whose blood rheology were the highest should be more predisposed to sudden deafness than the other patients.

  11. Onset time and haemodynamic response after thiopental vs. propofol in the elderly: a randomized trial

    DEFF Research Database (Denmark)

    Sørensen, Martin Kryspin; Dolven, T L; Rasmussen, L S

    2011-01-01

    The induction dose of hypnotic agents should be reduced in the elderly, but it is not well studied whether thiopental or propofol should be preferred in this group of patients. The aim of this study was to compare onset time, hypnosis level and the haemodynamic response after thiopental vs...

  12. Blood glutathione S-transferase-π as a time indicator of stroke onset.

    Directory of Open Access Journals (Sweden)

    Natacha Turck

    Full Text Available BACKGROUND: Ability to accurately determine time of stroke onset remains challenging. We hypothesized that an early biomarker characterized by a rapid increase in blood after stroke onset may help defining better the time window during which an acute stroke patient may be candidate for intravenous thrombolysis or other intravascular procedures. METHODS: The blood level of 29 proteins was measured by immunoassays on a prospective cohort of stroke patients (N = 103 and controls (N = 132. Mann-Whitney U tests, ROC curves and diagnostic odds ratios were applied to evaluate their clinical performances. RESULTS: Among the 29 molecules tested, GST-π concentration was the most significantly elevated marker in the blood of stroke patients (p3 h after onset. According to goal-oriented distinct cut-offs (sensitivity(Se-oriented: 17.7 or specificity(Sp-oriented: 65.2 ug/L, the GST-π test obtained 91%Se/50%Sp and 50%Se/91%Sp, respectively. Moreover, GST-π showed also the highest AUC (0.83 and performances for detecting patients treated with tPA (N = 12 compared to ineligible patients (N = 103. CONCLUSIONS: This study demonstrates that GST-π can accurately predict the time of stroke onset in over 50% of early stroke patients. The GST-π test could therefore complement current guidelines for tPA administration and potentially increase the number of patients accessing thrombolysis.

  13. Initial Stop Voicing in Bilingual Children With Cochlear Implants and Their Typically Developing Peers With Normal Hearing

    Science.gov (United States)

    Goodin-Mayeda, C. Elizabeth; Procter, Amanda; Hernandez, Arturo

    2016-01-01

    Purpose This study focuses on stop voicing differentiation in bilingual children with normal hearing (NH) and their bilingual peers with hearing loss who use cochlear implants (CIs). Method Twenty-two bilingual children participated in our study (11 with NH, M age = 5;1 [years;months], and 11 with CIs, M hearing age = 5;1). The groups were matched on hearing age and a range of demographic variables. Single-word picture elicitation was used with word-initial singleton stop consonants. Repeated measures analyses of variance with three within-subject factors (language, stop voicing, and stop place of articulation) and one between-subjects factor (NH vs. CI user) were conducted with voice onset time and percentage of prevoiced stops as dependent variables. Results Main effects were statistically significant for language, stop voicing, and stop place of articulation on both voice onset time and prevoicing. There were no significant main effects for NH versus CI groups. Both children with NH and with CIs differentiated stop voicing in their languages and by stop place of articulation. Stop voicing differentiation was commensurate across the groups of children with NH versus CIs. Conclusions Stop voicing differentiation is accomplished in a similar fashion by bilingual children with NH and CIs, and both groups differentiate stop voicing in a language-specific fashion. PMID:27366990

  14. Dioxin and Polychlorinated Biphenyl Concentrations in Mother's Serum and the Timing of Pubertal Onset in Sons

    Science.gov (United States)

    Humblet, Olivier; Williams, Paige L.; Korrick, Susan A.; Sergeyev, Oleg; Emond, Claude; Birnbaum, Linda S.; Burns, Jane S.; Altshul, Larisa; Patterson, Donald G.; Turner, Wayman E.; Lee, Mary M.; Revich, Boris; Hauser, Russ

    2013-01-01

    Background Animal studies have demonstrated that timing of pubertal onset can be altered by prenatal exposure to dioxins or polychlorinated biphenyls (PCBs), but studies of human populations have been quite limited. Methods We assessed the association between maternal serum concentrations of dioxins and PCBs and the sons’ age of pubertal onset in a prospective cohort of 489 mother–son pairs from Chapaevsk, Russia, a town contaminated with these chemicals during past industrial activity. The boys were recruited at ages 8 to 9 years, and 4 years of annual follow-up data were included in the analysis. Serum samples were collected at enrollment from both mothers and sons for measurement of dioxin and PCB concentrations using high-resolution mass spectrometry. The sons’ pubertal onset—defined as pubertal stage 2 or higher for genitalia (G) or pubic hair (P), or testicular volume >3 mL—was assessed annually by the same physician. Results In multivariate Cox models, elevated maternal serum PCBs were associated with earlier pubertal onset defined by stage G2 or higher (4th quartile hazard ratio = 1.7 [95% confidence interval = 1.1– 2.5]), but not for stage P2 or higher or for testicular volume >3 mL. Maternal serum concentrations of dioxin toxic equivalents were not consistently associated with the sons’ pubertal onset, although a dose-related delay in pubertal onset (only for G2 or higher) was seen among boys who breast-fed for 6 months or more. Conclusions Maternal PCB serum concentrations measured 8 or 9 years after sons’ births—which may reflect sons’ prenatal and early-life exposures—were associated with acceleration in some, but not all, measures of pubertal onset. PMID:21968773

  15. Is Time to Reach EDSS 6.0 Faster in Patients with Late-Onset versus Young-Onset Multiple Sclerosis?

    Science.gov (United States)

    Alroughani, Raed; Akhtar, Saeed; Ahmed, Samar; Behbehani, Raed; Al-Hashel, Jasem

    2016-01-01

    Published natural history data on late-onset of multiple sclerosis are limited. We aimed to assess the risk of attaining EDSS 6.0 among patients with late-onset (> 40 years) MS (LOMS) and young-onset (18-40 years) MS (YOMS). This cross-sectional cohort study was conducted to identify LOMS and YOMS patients' with relapsing remitting course at MS diagnosis. Time (years) to reach sustained EDSS 6.0 was compared between LOMS and AOMS patients. Cox proportional hazards model was used to evaluate the demographic and clinical predictors of time to EDSS 6.0 in these cohorts. LOMS and YOMS cohorts comprised 99 (10.7%) and 804 (89.3%) patients respectively. Spinal cord presentation at MS onset was more common among LOMS patients (46.5% vs. 32.3%). The proportions of LOMS and YOMS patients reaching EDSS 6.0 during the follow-up period were 19.2% and 15.7% respectively. In multivariable Cox proportional hazards model, older age at MS onset (adjusted hazard ratio (aHR) = 3.96; 95% CI: 2.14-7.32; p EDSS 6.0. LOMS patients attained EDSS 6.0 in a significantly shorter period that was influenced by male gender and spinal cord presentation at MS onset.

  16. Impact of sow and litter characteristics on colostrum yield, time for onset of lactation, and milk yield of sows

    DEFF Research Database (Denmark)

    Vadmand, Camilla Nielsen; Larsen, Uffe Krogh; Hansen, Christian Fink;

    2015-01-01

    The aim of the present study was to estimate the concurrent impact of sow and litter characteristics on sow productivity. Sow productivity was defined as colostrum yield (CY), onset of lactation (the time point when milk secretion increased steeply, approximately 31 h postpartum), transition milk...... time for onset of lactation was positively correlated with transition MY (P ... litter equlization, none of the observed independent variables were related with time for onset of lactation. In conclusion, when maximizing sow productivity in the future, it may be rewarding to pay attention to sow productivity in the colostrum period and around time for onset of lactation, and special...

  17. Impact of onset time of acute kidney injury on outcomes in patients with acute decompensated heart failure.

    Science.gov (United States)

    Takaya, Yoichi; Yoshihara, Fumiki; Yokoyama, Hiroyuki; Kanzaki, Hideaki; Kitakaze, Masafumi; Goto, Yoichi; Anzai, Toshihisa; Yasuda, Satoshi; Ogawa, Hisao; Kawano, Yuhei

    2016-01-01

    Since acute kidney injury (AKI) is not always related to mortality in patients with acute decompensated heart failure (ADHF), the aim of this study was to focus on onset time of AKI and its clinical importance. A total of 371 ADHF patients were included. The impact of AKI (≥ 0.3 mg/dl or 1.5-fold increase in serum creatinine level within 48 h) with early onset (≤ 4 days from admission) or late onset (≥ 5 days from admission) was assessed. AKI occurred in 99 patients, who were divided into two groups according to the median onset time of AKI: 50 with early onset of AKI and 49 with late onset of AKI. The maximum increase in serum creatinine level from admission was greater in patients with late onset of AKI than in patients with early onset of AKI (p = 0.012). Patients with late onset of AKI had a higher 12-month mortality rate than that in patients with early onset of AKI (log-rank test, p = 0.014). Late onset of AKI was an independent predictor of mortality (hazard ratio: 3.39, 95 % confidence interval: 1.84-6.18, p time of AKI may be useful for risk stratification of mortality in ADHF patients developing AKI.

  18. Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose

    Directory of Open Access Journals (Sweden)

    Hong Jin Lim

    Full Text Available Abstract Background and objectives: A high sodium concentration is known to antagonize local anesthetics when infiltrated around neural tissue. Thus, we hypothesized that the onset time for sensory and motor blockade, in supraclavicular brachial plexus block using ropivacaine diluted with dextrose would be shorter than with saline. Methods: Patients scheduled for upper limb surgery were randomized to receive ultrasound guided supraclavicular brachial plexus block with 0.5% ropivacaine. Evaluation of sensory and motor blockade was performed every 5 min for 60 min. Patients were followed-up on postoperative day 1, and between days 7 and 10 for the presence of any complications. Twenty-five patients in each group were analyzed. Results: Mean time for onset of analgesia for the dextrose group was 37.6 ± 12.9 min while the mean time for the saline group was 45.2 ± 13.9 min with a p-value of 0.05. The effect size was 0.567, which was moderate to large. No major complications were observed. Conclusion: We conclude that there was a decrease in onset time of analgesia when dextrose was used as a diluent instead of saline for ultrasound guided supraclavicular block.

  19. 局域网内实时语音传输实现%Real-time Voice Transfer Within LAN

    Institute of Scientific and Technical Information of China (English)

    吕银强

    2011-01-01

    The rapid development of media and Internet technology provided a possibility for video and audio communica-tion based on network. In the network communication, some voice from sending end should be transmitted to the receiving end real-timely. The real-time voice multicast system provided a good solution for the applications, which included three systems such as sending end, receiving end and network transmission. According to the principle of TCP/IP, route selection, transfer protocol, program implementation and so on, a perfect solution is proposed in this paper for realizing real-time transmission of voice signal within LAN. It has good reference and significance.%多媒体和网络技术的迅速发展为基于网络的视、音频通信提供了可能,在很多的网络通信中,都需要将某一发送端的话音实时的传输给接收端.实时语音组播系统为这些应用需求提供了一个不错的解决方案,实时语音组播系统可以分成发送端、接收端和网络传输3个子系统.在此从TCP/IP通信的原理,包括路由选择、传输协议、编程实现等角度,给出了比较完善的解决方案,从而实现了在局域网内语音信号的实时传输,有很好的参考和借鉴意义.

  20. Voice Disorders

    Science.gov (United States)

    Voice is the sound made by air passing from your lungs through your larynx, or voice box. In your larynx are your vocal cords, ... to make sound. For most of us, our voices play a big part in who we are, ...

  1. Every Voice

    Science.gov (United States)

    Patrick, Penny

    2008-01-01

    This article discusses how the author develops an approach that allows her students, who are part of the marginalized population, to learn the power of their own voices--not just their writing voices, but their oral voices as well. The author calls it "TWIST": Thoughts, Writing folder, Inquiring mind, Supplies, and Teamwork. It is where…

  2. Every Voice

    Science.gov (United States)

    Patrick, Penny

    2008-01-01

    This article discusses how the author develops an approach that allows her students, who are part of the marginalized population, to learn the power of their own voices--not just their writing voices, but their oral voices as well. The author calls it "TWIST": Thoughts, Writing folder, Inquiring mind, Supplies, and Teamwork. It is where…

  3. Voice restoration

    NARCIS (Netherlands)

    Hilgers, F.J.M.; Balm, A.J.M.; van den Brekel, M.W.M.; Tan, I.B.; Remacle, M.; Eckel, H.E.

    2010-01-01

    Surgical prosthetic voice restoration is the best possible option for patients to regain oral communication after total laryngectomy. It is considered to be the present "gold standard" for voice rehabilitation of laryngectomized individuals. Surgical prosthetic voice restoration, in essence, is alwa

  4. VoiceRelay: voice key operation using visual basic.

    Science.gov (United States)

    Abrams, Lise; Jennings, David T

    2004-11-01

    Using a voice key is a popular method for recording vocal response times in a variety of language production tasks. This article describes a class module called VoiceRelay that can be easily utilized in Visual Basic programs for voice key operation. This software-based voice key offers the precision of traditional voice keys (although accuracy is system dependent), as well as the flexibility of volume and sensitivity control. However, VoiceRelay is a considerably less expensive alternative for recording vocal response times because it operates with existing PC hardware and does not require the purchase of external response boxes or additional experiment-generation software. A sample project demonstrating implementation of the VoiceRelay class module may be downloaded from the Psychonomic Society Web archive, www.psychonomic.org/archive.

  5. The History and Timing of Depression Onset as Predictors of Young-Adult Self-Esteem

    Science.gov (United States)

    Lloyd, Donald A.; Ueno, Koji

    2010-01-01

    Depression often emerges early in the lifecourse and is consistently shown to be associated with poor self-esteem. The three main objectives of the current study are to (1) evaluate the association between a history major depression and self-esteem in young adulthood; (2) assess the relationship between timing of depression onset and young adult self-esteem; and (3) help rule out the alternative interpretation that the relationship between major depression and self-esteem is due to state dependence bias stemming from recent depressive symptoms and stressful life events. To address these objectives we use data from a two-wave panel study based on a community sample of young adults in Miami-Dade County, Florida (n = 1,197). Results indicated a history of major depression during sensitive periods of social development is associated with negative changes in self-esteem over a two-year period during the transition to young adulthood. Among those with a history of depression, earlier onset was more problematic than later onset for young adult self-esteem, although the difference disappeared once the level of self-esteem two years prior was controlled. The linkages between the history and timing of depression onset with self-esteem were observed net of recent depressive symptoms and stressful life events, and thus robust to an alternative interpretation of state dependence. The findings support the argument that major depression, especially if it develops earlier during child-adolescent development, has negative consequences for one’s self-esteem. PMID:21860585

  6. Time-frequency analysis of the Surge Onset in the Centrifugal Blower

    Directory of Open Access Journals (Sweden)

    Liskiewicz Grzegorz

    2015-09-01

    Full Text Available Time frequency analysis of the surge onset was performed in the centrifugal blower. A pressure signal was registered at the blower inlet, outlet and three locations at the impeller shroud. The time-frequency scalograms were obtained by means of the Continuous Wavelet Transform (CWT. The blower was found to successively operate in four different conditions: stable working condition, inlet recirculation, transient phase and deep surge. Scalograms revealed different spectral structures of aforementioned phases and suggest possible ways of detecting the surge predecessors.

  7. Contrastive voicing acquisition in 2-year-old children: Preliminary data

    Science.gov (United States)

    Hitchcock, Elaine R.; Koenig, Laura L.

    2004-05-01

    Earlier studies using voice-onset time (VOT) as the acoustic marker of contrastive voicing acquisition in English have differed widely in method and statistical procedures. Research in this area has shown three primary patterns of voicing acquisition for English stop consonants. One report indicates children demonstrate discrete voicing categories with adult-like VOT values as early as 2 years old. Other reports suggest a subperceptual distinction of the voicing contrast, followed by an exaggerated voicing contrast with evidence of more adult-like discrete categories by 3 years old. Still other reports suggest no distinction between the voicing categories until approximately 3 years. This work investigates voicing acquisition in three typically developing, English-speaking 2-year-old children. The subjects were recorded every 2 weeks for 4-6 months. Approximately 15-20 tokens were elicited for four target utterances containing initial /b p t d/. Frequency distribution, measures of central tendency, and skewness will be calculated for every recording session of each child. Discussion will focus on the development of contrastive VOT categories and their stability over time. These data will contribute to our understanding of laryngeal timing for English stop consonants in young children.

  8. Voice application development for Android

    CERN Document Server

    McTear, Michael

    2013-01-01

    This book will give beginners an introduction to building voice-based applications on Android. It will begin by covering the basic concepts and will build up to creating a voice-based personal assistant. By the end of this book, you should be in a position to create your own voice-based applications on Android from scratch in next to no time.Voice Application Development for Android is for all those who are interested in speech technology and for those who, as owners of Android devices, are keen to experiment with developing voice apps for their devices. It will also be useful as a starting po

  9. Response inhibition can affect reaction time to abrupt-onset visual displays.

    Science.gov (United States)

    Gellatly, Angus; Cole, Geoff; Fox, Claire; Johnson, Matthew

    2003-01-01

    Reaction time (RT) to abrupt-onset stimuli has been widely used for more than a century to measure the duration of perceptuo-cognitive and motor processes [Donders, 1868/1969 Attention and Performance II (1969 Acta Psychologica 30 412-431)]. A complicating factor with the RT method is that of response withholding, or response inhibition (RI). The occurrence of RI (under this or other names) has been widely discussed in relation to studies of motor processes but has been largely ignored in relation to studies of perceptuo-cognitive processes. We demonstrate that RI can be a confounding factor when RT to abrupt-onset displays is used to study perceptual and cognitive processes. In experiment 1, new-object targets were more accurately detected than old-object targets in an unspeeded task, but were responded to more slowly in an RT task. Consistent with an interpretation in terms of RI, this pattern of results was dependent on the difficulty of target detection. The data of three further experiments also support predictions from the RI interpretation. It is suggested that RI may be an under-acknowledged factor in RT studies of perceptual and cognitive processes with abrupt-onset displays.

  10. The interaction of tone with voicing and foot structure: evidence from Kera phonetics and phonology

    Science.gov (United States)

    Pearce, Mary Dorothy

    This thesis uses acoustic measurements as a basis for the phonological analysis of the interaction of tone with voicing and foot structure in Kera (a Chadic language). In both tone spreading and vowel harmony, the iambic foot acts as a domain for spreading. Further evidence for the foot comes from measurements of duration, intensity and vowel quality. Kera is unusual in combining a tone system with a partially independent metrical system based on iambs. In words containing more than one foot, the foot is the tone bearing unit (TBU), but in shorter words, the TBU is the syllable. In perception and production experiments, results show that Kera speakers, unlike English and French, use the fundamental frequency as the principle cue to 'Voicing" contrast. Voice onset time (VOT) has only a minor role. Historically, tones probably developed from voicing through a process of tonogenesis, but synchronically, the feature voice is no longer contrastive and VOT is used in an enhancing role. Some linguists have claimed that Kera is a key example for their controversial theory of long-distance voicing spread. But as voice is not part of Kera phonology, this thesis gives counter-evidence to the voice spreading claim. An important finding from the experiments is that the phonological grammars are different between village women, men moving to town and town men. These differences are attributed to French contact. The interaction between Kera tone and voicing and contact with French have produced changes from a 2-way voicing contrast, through a 3-way tonal contrast, to a 2-way voicing contrast plus another contrast with short VOT. These diachronic and synchronic tone/voicing facts are analysed using laryngeal features and Optimality Theory. This thesis provides a body of new data, detailed acoustic measurements, and an analysis incorporating current theoretical issues in phonology, which make it of interest to Africanists and theoreticians alike.

  11. Estimating the time of melt onset and freeze onset over Arctic sea-ice area using active and passive microwave data

    Science.gov (United States)

    Belchansky, G.I.; Douglas, D.C.; Mordvintsev, I.N.; Platonov, N.G.

    2004-01-01

    Accurate calculation of the time of melt onset, freeze onset, and melt duration over Arctic sea-ice area is crucial for climate and global change studies because it affects accuracy of surface energy balance estimates. This comparative study evaluates several methods used to estimate sea-ice melt and freeze onset dates: (1) the melt onset database derived from SSM/I passive microwave brightness temperatures (Tbs) using Drobot and Anderson's [J. Geophys. Res. 106 (2001) 24033] Advanced Horizontal Range Algorithm (AHRA) and distributed by the National Snow and Ice Data Center (NSIDC); (2) the International Arctic Buoy Program/Polar Exchange at the Sea (IABP/POLES) surface air temperatures (SATs); (3) an elaborated version of the AHRA that uses IABP/POLES to avoid anomalous results (Passive Microwave and Surface Temperature Analysis [PMSTA]); (4) another elaborated version of the AHRA that uses T b variance to avoid anomalous results (Mean Differences and Standard Deviation Analysis [MDSDA]); (5) Smith's [J. Geophys. Res. 103 (1998) 27753] vertically polarized Tb algorithm for estimating melt onset in multiyear (MY) ice (SSM/I 19V-37V); and (6) analyses of concurrent backscattering cross section (????) and brightness temperature (T b) from OKEAN-01 satellite series. Melt onset and freeze onset maps were created and compared to understand how the estimates vary between different satellite instruments and methods over different Arctic sea-ice regions. Comparisons were made to evaluate relative sensitivities among the methods to slight adjustments of the Tb calibration coefficients and algorithm threshold values. Compared to the PMSTA method, the AHRA method tended to estimate significantly earlier melt dates, likely caused by the AHRA's susceptibility to prematurely identify melt onset conditions. In contrast, the IABP/POLES surface air temperature data tended to estimate later melt and earlier freeze in all but perennial ice. The MDSDA method was least sensitive to

  12. [Reproductive season onset and time invested in territory defense in Colinus leucopogon males (Galliformes: Odontophoridae)].

    Science.gov (United States)

    Sandoval, Luis

    2011-03-01

    The factors that determine the onset of the reproductive season and the relationship between territory defense and mating success of Colinus leucopogon males are unknown. Here I report on climatic variables influencing the time of permanence on the territory, and how this affects the species mating success. I also analyze the relationship between the time devoted by males on territory defense and the relationship of song and territorial characteristics. The onset of the reproductive season was determined by an amount of rain greater than 14.3 mm during March, favouring the food availability and nesting places abundance, and also allowed an increase in the reproductive success of Colinus leucopogon. The time invested in territory defense by males was not related with their mating success. Moreover, the duration in territory defense was similar for males that paired, compared with those that did not. In addition, song and territory characteristics were not related with males invested time in their territory defense. Therefore, this could be another reason explaining the lack of a relationship between the duration in the territories by males and pair formation, and suggests that song characteristics strongly influence the formation of pairs in this species.

  13. Time from onset of SIRS to antibiotic administration and outcomes after subarachnoid hemorrhage.

    Science.gov (United States)

    Guterman, Elan L; Kamel, Hooman; Azran, Carmil; Shah, Maulik P; Claude Hemphill, J; Smith, Wade S; Navi, Babak B

    2014-08-01

    The interval from presentation with systemic inflammatory response syndrome (SIRS) to the start of antibiotic administration affects mortality in patients with sepsis. However, patients with subarachnoid hemorrhage (SAH) often develop SIRS directly from their brain injury, making it a less useful indicator of infection. We therefore hypothesized that SIRS would not be a suitable trigger for antibiotics in this population. We examined the time from the development of SIRS until antibiotic initiation and its relationship to long-term neurological outcomes in patients with nontraumatic SAH. Patients' baseline characteristics, time of antibiotic administration, and hospital course were collected from retrospective chart review. The primary outcome, 6-month functional status, was prospectively determined using blinded, structured interviews incorporating the modified Rankin Scale (mRS). Sixty-six of 70 patients with SAH during the study period had 6-month follow-up and were included in this analysis. SIRS developed in 57 patients (86%, 95% CI 78-95%). In ordinal logistic regression models controlling for age and illness severity, the time from SIRS onset until antibiotic initiation was not associated with 6-month mRS scores (OR per hour, 0.994; 95% CI 0.987-1.001). In this cohort of patients with SAH, time from SIRS onset until antibiotic administration was not related to functional outcomes. Our results indicate that SIRS is nonspecific in patients with SAH, and support the safety of withholding antibiotics in those who lack additional evidence of infection or hemodynamic deterioration.

  14. Time perspective and early-onset substance use: a model based on stress-coping theory.

    Science.gov (United States)

    Wills, T A; Sandy, J M; Yaeger, A M

    2001-06-01

    This research tested the relation of time perspective to early-onset substance use (tobacco, alcohol, and marijuana) with a sample of 454 elementary school students with a mean age of 11.8 years. An adaptation of the Zimbardo Time Perspective Inventory (P. G. Zimbardo & J. N. Boyd, 1999) was administered with measures derived from stress-coping theory. Independent effects showed future orientation inversely related to substance use and present orientation positively related to substance use. Structural modeling analysis indicated that the relation of time perspective measures to substance use was indirect, mediated through behavioral coping and anger coping. Proximal factors for substance use were negative affect, peer substance use, and resistance efficacy. Results are discussed with respect to epigenetic models and the role of executive functions in self-control ability.

  15. Childhood and adolescent onset psychiatric disorders, substance use, and failure to graduate high school on time.

    Science.gov (United States)

    Breslau, Joshua; Miller, Elizabeth; Joanie Chung, W-J; Schweitzer, Julie B

    2011-03-01

    We examined the joint predictive effects of childhood and adolescent onset psychiatric and substance use disorders on failure to graduate high school (HS) on time. Structured diagnostic interviews were conducted with a US national sample of adults (18 and over). The analysis sample included respondents with at least 8 years of education who were born in the US or arrived in the US prior to age 13 (N = 29,662). Psychiatric disorders, substance use and substance use disorders were examined as predictors of termination or interruption of educational progress prior to HS graduation, with statistical adjustment for demographic characteristics and childhood adversities. Failure to graduate HS on time was more common among respondents with any of the psychiatric and substance use disorders examined, ranging from 18.1% (specific phobia) to 33.2% (ADHD-combined type), compared with respondents with no disorder (15.2%). After adjustment for co-occurring disorders, significant associations with failure to graduate on time remained only for conduct disorder (OR = 1.89, 95% CI 1.57-2.26) and the three ADHD subtypes (Inattentive OR = 1.78, 95% CI 1.44-2.20, Hyperactive-Impulsive OR = 1.38, 95% CI 1.14-1.67, and Combined OR = 2.06, 95% CI 1.66-2.56). Adjusting for prior disorders, tobacco use was associated with failure to graduate on time (OR = 1.97, 95% CI 1.80-2.16). Among substance users, substance use disorders were not associated with on-time graduation. The findings suggest that the adverse impact of childhood and adolescent onset psychiatric disorders on HS graduation is largely accounted for by problems of conduct and inattention. Adjusting for these disorders, smoking remains strongly associated with failure to graduate HS on time.

  16. The value of serial personal photographs in timing the onset of unilateral cataracts in children.

    Science.gov (United States)

    Sawhney, Gagan K; Hutchinson, Amy K; Lambert, Scott R

    2009-10-01

    To determine the value of serial personal photographs in timing the onset of unilateral cataracts in children over 6 months of age. Personal photographs from children with unilateral cataracts who underwent cataract extraction and intraocular lens implantation when > or =6 months of age were reviewed. Photographs were evaluated for changes in the red reflex, which might indicate the presence of a cataract. Twelve children underwent cataract surgery at a mean age of 37 months. They were followed for a mean of 32 months. Ten children were diagnosed as having an acquired cataract by photographic review documenting a previously normal red reflex. The visual acuity in the affected eye of 4 of these children improved to > or =20/60. Cataracts were visible on photographs prior to clinical diagnosis in 6 patients, from 0.5 to 22 months prior to clinical diagnosis. Visual outcomes did not relate closely to the photographically documented duration of the cataract prior to treatment. Photographs were not helpful in timing the onset of cataract in 2 children due to the poor quality of the images. Serial personal photographs are sometimes helpful in determining whether cataracts are acquired. However, the usefulness of personal photographs alone in predicting the visual outcome after cataract surgery was limited in this small, retrospective study.

  17. Meteorological factors and the time of onset of chest pain in acute myocardial infarction

    Science.gov (United States)

    Thompson, David R.; Pohl, Jurgen E.; Tse, Yiu-Yu S.; Hiorns, Robert W.

    1996-09-01

    Analysis of the time of onset of chest pain in 2254 patients with a myocardial infarction admitted to a coronary care unit in Leicester during a 10-year period shows an association with temperature and humidity. During both the most cold and humid times of the year, the relationship is a strong one. A generalized linear model with a log link was used to fit the data and the backward elimination selection procedure suggested a humid, cold day might help to trigger the occurrence of myocardial infarction. In addition, cold weather was found to have a stronger effect on the male population while those men aged between 50 and 70 years were more sensitive to the effect of high humidity.

  18. A Real-Time Face Motion Based Approach towards Modeling Socially Assistive Wireless Robot Control with Voice Recognition

    Directory of Open Access Journals (Sweden)

    Abhinaba Bhattacharjee

    2015-10-01

    Full Text Available The robotics domain has a couple of specific general design requirements which requires the close integration of planning, sensing, control and modeling and for sure the robot must take into account the interactions between itself, its task and its environment surrounding it. Thus considering the fundamental configurations, the main motive is to design a system with user-friendly interfaces that possess the ability to control embedded robotic systems by natural means. While earlier works have focused primarily on issues such as manipulation and navigation only, this proposal presents a conceptual and intuitive approach towards man-machine interaction in order to provide a secured live biometric logical authorization to the user access, while making an intelligent interaction with the control station to navigate advanced gesture controlled wireless Robotic prototypes or mobile surveillance systems along desired directions through required displacements. The intuitions are based on tracking real-time 3-Dimensional Face Motions using skin tone segmentation and maximum area considerations of segmented face-like blobs, Or directing the system with voice commands using real-time speech recognition. The system implementation requires designing a user interface to communicate between the Control station and prototypes wirelessly, either by accessing the internet over an encrypted Wi-Fi Protected Access (WPA via a HTML web page for communicating with face motions or with the help of natural voice commands like “Trace 5 squares”, “Trace 10 triangles”, “Move 10 meters”, etc. evaluated on an iRobot Create over Bluetooth connectivity using a Bluetooth Access Module (BAM. Such an implementation can prove to be highly effective for designing systems of elderly aid and maneuvering the physically challenged.

  19. Voice Enhancement, Time-Frequency Analysis and GUI Design of Airplane cockpit voice in MATLAB%MATLAB飞机舱音语音增强、时频分析和GUI设计

    Institute of Scientific and Technical Information of China (English)

    万守鹏; 石钢; 程道来; 纪林章; 周志浩

    2014-01-01

    舱音记录器中的声信息对失事飞机原因调查十分重要。在分析舱音声信息的特殊性和MATLAB数学软件强大功能和优势基础上,从录制的多个典型舱音中选取其中的“火警警铃”舱音样本为例,设计了MATLAB环境的载入程序,避免了类似于C语言的循环语句等编程复杂等问题,完成舱音信息的时频分析与处理,得到期望的效果。最后在MATLAB图形用户界面(GUI)设计出适合人机对话的操作流程,使得舱音分析过程简单、实用,并在典型舱音分析中得到验证。%The voice signal in cockpit voice recorder (CVR) is very important forifnding the cause of aircraft accident. First explain the particularity of such voice and MATLAB’s powerful function, then takeifre alarm as an example to design load program in MATLAB environment, dispose time-frequency analysis and get the results. Its advantage is avoided the complexity and the long operation time like C program. Finally work out the interface that suitable for the man-machine conversation in graphical user interface (GUI). It is conifrmed with typical cockpit voices and make the analysis procedure simpler and more practical.

  20. Voice identity recognition: functional division of the right STS and its behavioral relevance.

    Science.gov (United States)

    Schall, Sonja; Kiebel, Stefan J; Maess, Burkhard; von Kriegstein, Katharina

    2015-02-01

    The human voice is the primary carrier of speech but also a fingerprint for person identity. Previous neuroimaging studies have revealed that speech and identity recognition is accomplished by partially different neural pathways, despite the perceptual unity of the vocal sound. Importantly, the right STS has been implicated in voice processing, with different contributions of its posterior and anterior parts. However, the time point at which vocal and speech processing diverge is currently unknown. Also, the exact role of the right STS during voice processing is so far unclear because its behavioral relevance has not yet been established. Here, we used the high temporal resolution of magnetoencephalography and a speech task control to pinpoint transient behavioral correlates: we found, at 200 msec after stimulus onset, that activity in right anterior STS predicted behavioral voice recognition performance. At the same time point, the posterior right STS showed increased activity during voice identity recognition in contrast to speech recognition whereas the left mid STS showed the reverse pattern. In contrast to the highly speech-sensitive left STS, the current results highlight the right STS as a key area for voice identity recognition and show that its anatomical-functional division emerges around 200 msec after stimulus onset. We suggest that this time point marks the speech-independent processing of vocal sounds in the posterior STS and their successful mapping to vocal identities in the anterior STS.

  1. A time-transgressive Holocene onset from Globorotalia menardii records on Brazilian continental margin sediments

    Science.gov (United States)

    Iwai, F. S.; Costa, K. B.; Toledo, F. A. D. L.; Santarosa, A. C. A.; Chiessi, C. M.; Camillo, E., Jr.; Quadros, J. P.

    2014-12-01

    The planktic foraminifer Globorotalia menardii presents a cyclic behavior within Pleistocene glacial cycles on Atlantic; it disappears during glacial periods and returns to this ocean after deglaciations. Therefore, G. menardii has been used to identify limits between those cycles and the last limit is recognized as the Holocene onset. The Holocene onset has been reported before as being more than 4 kyrs later than expected at the equatorial Atlantic Ocean based on a G. menardii record (Broecker & Pena, 2014). In this study, we explore the time-transgressive Holocene onset of G. menardii in the Atlantic from 21 piston cores collected along the Brazilian continental margin, between 7 ˚N and 33 ˚S. Radiocarbon dating was conducted on Globigerinoides ruber on samples prior to and after G. menardii reappearance in the cores. Reservoir-age corrected 14C dates vary between 17 and 6.5 cal kyrs; the older ages are found at ~14 ˚S and younger ages at 6 ˚N and 33 ˚S. From these ages and latitudes, we hypothesize that G. menardii's population has spread at higher rates southward. From the scenario observed on Brazilian coast it is possible to conclude that although ocean circulation has an important role on dispersion of planktonic foraminifera, it may be superimposed by ecological constraints of the species. G. menardii absence during glacials is linked to the Agulhas Leakage activity, which is prevented from getting to the Atlantic due the northern position of the Subtropical Convergence Zone during glacials. On interglacials, warm and saline waters carrying G. menardii are transported into the Subtropical Gyre currents, achieving Brazil's coast through the South Equatorial Current and spreading south and northward through Brazil Current and North Brazil Current, respectively. Nonetheless, from velocity and volume registered for this currents, we would expect a higher G. menardii dispersion rate northward. A faster southward dispersal during the deglaciation suggests

  2. Time since onset of disease and individual clinical markers associate with transcriptional changes in uncomplicated dengue.

    Directory of Open Access Journals (Sweden)

    Cornelia A M van de Weg

    2015-03-01

    Full Text Available BACKGROUND: Dengue virus (DENV infection causes viral haemorrhagic fever that is characterized by extensive activation of the immune system. The aim of this study is to investigate the kinetics of the transcriptome signature changes during the course of disease and the association of genes in these signatures with clinical parameters. METHODOLOGY/PRINCIPLE FINDINGS: Sequential whole blood samples from DENV infected patients in Jakarta were profiled using affymetrix microarrays, which were analysed using principal component analysis, limma, gene set analysis, and weighted gene co-expression network analysis. We show that time since onset of disease, but not diagnosis, has a large impact on the blood transcriptome of patients with non-severe dengue. Clinical diagnosis (according to the WHO classification does not associate with differential gene expression. Network analysis however, indicated that the clinical markers platelet count, fibrinogen, albumin, IV fluid distributed per day and liver enzymes SGOT and SGPT strongly correlate with gene modules that are enriched for genes involved in the immune response. Overall, we see a shift in the transcriptome from immunity and inflammation to repair and recovery during the course of a DENV infection. CONCLUSIONS/SIGNIFICANCE: Time since onset of disease associates with the shift in transcriptome signatures from immunity and inflammation to cell cycle and repair mechanisms in patients with non-severe dengue. The strong association of time with blood transcriptome changes hampers both the discovery as well as the potential application of biomarkers in dengue. However, we identified gene expression modules that associate with key clinical parameters of dengue that reflect the systemic activity of disease during the course of infection. The expression level of these gene modules may support earlier detection of disease progression as well as clinical management of dengue.

  3. "Science Isn't Just What We Learn in School": Interaction Rituals That Value Youth Voice in Out-of- School-Time Science

    Science.gov (United States)

    Gonsalves, Allison J.

    2014-01-01

    In this article, I explore what happens when digital media activities designed to stimulate science conversations are introduced to an out-of-school-time (OST) space usually reserved for talks about girls' issues. The goals of this study were to provide a space that values youth voice and creates positive emotional energy around science-related…

  4. Bifurcation onset delay in magnetic bearing systems by time varying stiffness

    Science.gov (United States)

    Ghazavi, M. R.; Sun, Q.

    2017-06-01

    We study the nonlinear dynamics behaviours of a rigid rotor supported by magnetic bearings. In particular, we consider the effect of rotor unbalanced mass and geometric coupling. Existing works in literature have mostly focused on a single value of parameter or a smaller range of the nonlinearities introduced by rotor imbalance and geometric coupling. This is partly due to the use of a linear PD controller which limits the system performance. In this paper, we use a nonlinear PD controller by adopting a time varying stiffness term. The control gains are chosen according to the stability chart for a Mathieu's equation. Consequently, we observe a delay in the onset of bifurcation indicating an improved rotor performance.

  5. P wave onset time picking with the B-spline biorthogonal wavelet

    Institute of Scientific and Technical Information of China (English)

    TENG Yun-tian; WANG Xi-zhen; WANG Xiao-mei; MA Jie-mei; XU Jian-hua

    2006-01-01

    @@ The seismic wave consists of many seismic phases, which contain rich geophysical information from the hypocenter, medium of seismic wave passing through and so on. It is very important to detect and pick these seismic phases for understanding the mechanism of earthquake, the Earth structure and property of seismic waves. In order to reduce or avoid the loss resulted from the earthquake, one of the important goals of seismic event detecting is to obtain its related information before and after it occurs. Because of the particularity of P wave and S wave,the seismic event detecting focuses on distinguishing P and S waves and picking their onset time, it has been becoming one of the research hotspots for many geophysicists to pick the P and S wave arrival accurately and effectively.

  6. Global Auroral Energy Deposition during Substorm Onset Compared with Local Time and Solar Wind IMF Conditions

    Science.gov (United States)

    Spann, J. F.; Brittnacher, M.; Fillingim, M. O.; Germany, G. A.; Parks, G. K.

    1998-01-01

    The global images made by the Ultraviolet Imager (UVI) aboard the IASTP/Polar Satellite are used to derive the global auroral energy deposited in the ionosphere resulting from electron precipitation. During a substorm onset, the energy deposited and its location in local time are compared to the solar wind IMF conditions. Previously, insitu measurements of low orbiting satellites have made precipitating particle measurements along the spacecraft track and global images of the auroral zone, without the ability to quantify energy parameters, have been available. However, usage of the high temporal, spatial, and spectral resolution of consecutive UVI images enables quantitative measurement of the energy deposited in the ionosphere not previously available on a global scale. Data over an extended period beginning in January 1997 will be presented.

  7. The Onset and Time Course of Semantic Priming During Rapid Recognition of Visual Words.

    Science.gov (United States)

    Hoedemaker, Renske S; Gordon, Peter C

    2017-02-23

    In 2 experiments, we assessed the effects of response latency and task-induced goals on the onset and time course of semantic priming during rapid processing of visual words as revealed by ocular response tasks. In Experiment 1 (ocular lexical decision task), participants performed a lexical decision task using eye movement responses on a sequence of 4 words. In Experiment 2, the same words were encoded for an episodic recognition memory task that did not require a metalinguistic judgment. For both tasks, survival analyses showed that the earliest observable effect (divergence point [DP]) of semantic priming on target-word reading times occurred at approximately 260 ms, and ex-Gaussian distribution fits revealed that the magnitude of the priming effect increased as a function of response time. Together, these distributional effects of semantic priming suggest that the influence of the prime increases when target processing is more effortful. This effect does not require that the task include a metalinguistic judgment; manipulation of the task goals across experiments affected the overall response speed but not the location of the DP or the overall distributional pattern of the priming effect. These results are more readily explained as the result of a retrospective, rather than a prospective, priming mechanism and are consistent with compound-cue models of semantic priming. (PsycINFO Database Record

  8. Voice and silence in organizations

    Directory of Open Access Journals (Sweden)

    Moaşa, H.

    2011-01-01

    Full Text Available Unlike previous research on voice and silence, this article breaksthe distance between the two and declines to treat them as opposites. Voice and silence are interrelated and intertwined strategic forms ofcommunication which presuppose each other in such a way that the absence of one would minimize completely the other’s presence. Social actors are not voice, or silence. Social actors can have voice or silence, they can do both because they operate at multiple levels and deal with multiple issues at different moments in time.

  9. Statins reduce new-onset atrial fibrillation in a first-time myocardial infarction population

    DEFF Research Database (Denmark)

    Bang, Casper N; Gislason, Gunnar H; Greve, Anders M

    2014-01-01

    AIM: To evaluate the effect of statins on reducing new-onset atrial fibrillation (AF) in a large real-world post-myocardial infarction (MI) population. Subsequently, to test if different statin doses, various types and compliance affected the incidence of new-onset AF post MI. METHODS: All patien...

  10. Timing of stroke onset determines discharge-functional status but not stroke severity: A hospital-based study

    Directory of Open Access Journals (Sweden)

    Li-Min Liou

    2013-01-01

    Full Text Available Circadian variation of the onset time of acute ischemic stroke has been well studied. However, little is mentioned about the circadian variation of discharge-stroke severity and discharge-functional status. This study evaluated the impact of onset time on discharge-stroke severity and the functional status of acute ischemic stroke. Brain magnetic resonance imaging was performed on 274 acute ischemic stroke patients (66.42% male; mean age = 64.81 ± 12.80 years. All times of onset were assigned to 4-hourly periods (six groups starting from midnight. Stroke severity/functional status was evaluated on admission and discharge using the National Institute of Health Stroke Scale (NIHSS score/modified Rankin Scale (mRS and Barthel Index (BI, respectively. Using mRS, but not NIHSS score and BI, it was possible to differentiate the best and worst groups on discharge. Patients in group 2 (4 to <8 am and group 6 (8 to <12 pm had best and worst functional status, respectively. To control other stroke risk factors, multiple logistic regression analyses were conducted to examine the role of onset time in discharge mRS. Aside from age, onset time was a significant indicator in mRS, while gender, hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, and current smoking were not. In conclusion, there is also circadian variation of discharge-functional status in patients with acute ischemic stroke when assessed by mRS.

  11. Loss of independent limb control in childhood hemiparesis is related to time of brain injury onset.

    Science.gov (United States)

    Sukal-Moulton, Theresa; Murray, Theresa M; Dewald, Julius P A

    2013-03-01

    This study investigated the presence of inter-limb activity at the elbow joint in individuals with childhood-onset hemiparesis, including spontaneous mirror movements during unilateral tasks and the ability to suppress them during bilateral tasks. Eighteen individuals with hemiparesis were divided into three categories of injury timing: before birth (PRE-natal), around the time of birth (PERI-natal), and after 6 months of age (POST-natal). Individuals with hemiparesis, as well as 12 typically developing peers, participated in unilateral and bilateral elbow flexion and extension tasks completed at maximal and submaximal effort while muscle activity was monitored and motor output was quantified by two multiple degrees-of-freedom load cells. Significantly, higher levels of paretic elbow flexion were found only in the PRE- and PERI-natal groups during the flexion of the non-paretic limb, which was modulated by effort level in both unilateral and bilateral tasks. The bilateral activation of elbow flexors in the PRE-/PERI-natal groups indicates potential use of a common cortical command source to drive both upper extremities, while the POST-natal/typically developing groups' flexors appear to receive input from different supraspinal structures.

  12. Dose dependency of time of onset of radiation-induced growth hormone deficiency

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, P.E.; Shalet, S.M. (Christie Hospital and Holt Radium Institute, Manchester (England))

    1991-02-01

    Growth hormone (GH) secretion during insulin-induced hypoglycemia was assessed on 133 occasions in 82 survivors of childhood malignant disease. All had received cranial irradiation with a dose range to the hypothalamic-pituitary axis of 27 to 47.5 Gy (estimated by a schedule of 16 fractions over 3 weeks) and had been tested on one or more occasions between 0.2 and 18.9 years after treatment. Results of one third of the GH tests were defined as normal (GH peak response, greater than 15 mU/L) within the first 5 years, in comparison with 16% after 5 years. Stepwise multiple linear regression analysis showed that dose (p = 0.007) and time from irradiation (p = 0.03), but not age at therapy, had a significant influence on peak GH responses. The late incidence of GH deficiency was similar over the whole dose range (4 of 26 GH test results normal for less than 30 Gy and 4 of 25 normal for greater than or equal to 30 Gy after 5 years), but the speed of onset over the first years was dependent on dose. We conclude that the requirement for GH replacement therapy and the timing of its introduction will be influenced by the dose of irradiation received by the hypothalamic-pituitary axis.

  13. Influence of classroom acoustics on the voice levels of teachers with and without voice problems: a field study

    DEFF Research Database (Denmark)

    Pelegrin Garcia, David; Lyberg-Åhlander, Viveka; Rydell, Roland

    2010-01-01

    Many teachers suffer from voice problems and classroom acoustics has been considered as one of the potential hazards for this. The present study examines how classroom acoustics interacts with the voices of 14 teachers without voice problems and 13 teachers with voice problems. The assessment...... of Reverberation Time and Voice Support were measured in the 30 empty classrooms of the study. An empirical model shows that the measured voice levels depended on the activity noise levels and the voice support. Teachers with and without voice problems were differently affected by the voice support...... of the classroom. The results thus suggest that teachers with voice problems are more aware of classroom acoustic conditions than their healthy colleagues and make use of the more supportive rooms to lower their voice levels. This behavior may result from an adaptation process of the teachers with voice problems...

  14. Keeping Your Voice Healthy

    Science.gov (United States)

    ... Find an ENT Doctor Near You Keeping Your Voice Healthy Keeping Your Voice Healthy Patient Health Information ... heavily voice-related. Key Steps for Keeping Your Voice Healthy Drink plenty of water. Moisture is good ...

  15. Effect of Small-dose of Ephedrine Administered Prior to Induction of Anesthesia on the Onset Time of Succinylcholine

    Directory of Open Access Journals (Sweden)

    S Atashkhoyi

    2007-10-01

    Full Text Available Introduction & Objective: Onset of action of relaxants is influenced by cardiac output and muscle blood flow. Ephedrine increases blood flow to muscles and may shorten the onset of action of succinylcholine. The aim of this study was to evaluate the effect of small-dose of ephedrine administered prior to rapid-sequence induction of anesthesia on the onset time of succinylcholine for endotracheal intubation. Materials & Methods: In this randomized clinical trial, 60 patients scheduled for elective gynecologic surgeries in Alzahra hospital in Tabriz 1385, were selected. In these patients ephedrine, 70 µg/kg (study group, n=30, or saline (placebo group, n=30 was administered 3 minutes before induction of anesthesia with thiopentone/fentanyl. Succinylcholine, 0.6 mg/kg, was administrated to facilitate the tracheal intubation. Onset of succinylcholine, intubating conditions and hemodynamic variables were recorded in the subjects. Results: Fasciculation was absent in 60% (36 of the patients. No significant differences were found between the onsets of fasciculation between two groups. Moreover, the difference in duration of fasciculation in two groups was not significant. Onset time of succinylcholine was significantly shorter in study group (19.53±3.91 second, compared with placebo group (25.87±7.11 second (p<0.0001. Patients in study group were intubated in 47.07±4.51 seconds compared with 58.73±9.04 seconds in placebo group (p<0.0001. Intubation conditions were similar in both groups. Heart rate was slightly increased in study patients in the first and 3rd minutes after ephedrine administration, but there was no significant difference in systolic blood pressure values compared with the baseline value between two groups. Conclusion: The onset time of succinylcholine is shortened with small-dose of ephedrine pretreatment without significant adverse heamodynamic effects.

  16. The time of onset of abnormal calcification in spondylometaepiphyseal dysplasia, short limb-abnormal calcification type

    Energy Technology Data Exchange (ETDEWEB)

    Tueysuez, Beyhan [Istanbul University, Department of Pediatric Genetics, Cerrahpasa Medical School, Istanbul (Turkey); Gazioglu, Nurperi [Istanbul University, Department of Neurosurgery, Cerrahpasa Medical School, Istanbul (Turkey); Uenguer, Savas [Istanbul University, Department of Pediatric Radiology, Cerrahpasa Medical School, Istanbul (Turkey); Aji, Dolly Yafet [Istanbul University, Department of Pediatrics, Cerrahpasa Medical School, Istanbul (Turkey); Tuerkmen, Seval [Istanbul University, Department of Pediatric Genetics, Cerrahpasa Medical School, Istanbul (Turkey); Universitatsklinikum Berlin, Charite Virchow-Klinik, Berlin (Germany)

    2009-01-15

    A 1-month-old boy with shortness of extremities on prenatal US was referred to our department with a provisional diagnosis of achondroplasia. His height was normal but he had short extremities and platyspondyly, premature carpal epiphyses on both hands, and short tubular bones with irregular metaphyses on radiographs. Re-evaluation of the patient at the age of 1 year revealed very short height and premature calcification of the costal cartilages and epiphyses. Spondylometaepiphyseal dysplasia (SMED), short limb-abnormal calcification type was diagnosed. This condition is a very rare autosomal recessively inherited disorder, and most of the patients die in early childhood due to neurological involvement. At the age of 2 years and 5 months, a CT scan showed narrowing of the cervical spinal canal. One month later he died suddenly because of spinal cord injury. In conclusion early diagnosis is very important because the recurrence risk is high and patients may die due to early neurological complications. The time of onset of abnormal calcifications, a diagnostic finding of the disease, is at the age of around 1 year in most patients. When abnormal calcifications are not yet present, but radiological changes associated with SMED are present, this rare disease must be considered. (orig.)

  17. The time of onset of abnormal calcification in spondylometaepiphyseal dysplasia, short limb-abnormal calcification type.

    Science.gov (United States)

    Tüysüz, Beyhan; Gazioğlu, Nurperi; Ungür, Savaş; Aji, Dolly Yafet; Türkmen, Seval

    2009-01-01

    A 1-month-old boy with shortness of extremities on prenatal US was referred to our department with a provisional diagnosis of achondroplasia. His height was normal but he had short extremities and platyspondyly, premature carpal epiphyses on both hands, and short tubular bones with irregular metaphyses on radiographs. Re-evaluation of the patient at the age of 1 year revealed very short height and premature calcification of the costal cartilages and epiphyses. Spondylometaepiphyseal dysplasia (SMED), short limb-abnormal calcification type was diagnosed. This condition is a very rare autosomal recessively inherited disorder, and most of the patients die in early childhood due to neurological involvement. At the age of 2 years and 5 months, a CT scan showed narrowing of the cervical spinal canal. One month later he died suddenly because of spinal cord injury. In conclusion early diagnosis is very important because the recurrence risk is high and patients may die due to early neurological complications. The time of onset of abnormal calcifications, a diagnostic finding of the disease, is at the age of around 1 year in most patients. When abnormal calcifications are not yet present, but radiological changes associated with SMED are present, this rare disease must be considered.

  18. Time of delirium onset and prognosis amongst Southern Brazilian hospitalized elderly patients

    Directory of Open Access Journals (Sweden)

    André Luiz Moschetta

    Full Text Available Abstract The prognostic significance of delirium in hospitalized elderly has not yet been fully clarified. Objectives: The present study was designed to evaluate the relationship between prevalent delirium (PrD, incident delirium (InD and final outcome. Methods: A historical cohort of 261 patients was selected. delirium was diagnosed using the Confusion Assessment Method. Results: The total frequency of delirium detected was 42.5%-31.4% PrD and 16.2% InD. Among patients with InD, the average length of hospital stay was 9.1 days longer than for patients without delirium (p=0.002, and the hospital mortality associated with InD was 48% versus 2.7% for those without delirium (p<0.001. However, no difference was observed between patients with PrD and those without delirium. Conclusions: These results suggest that, when investigating delirium and prognosis amongst hospitalized elderly, it is fundamental to differentiate in terms of time of onset. Furthermore, the absence of delirium seems to be an important protective factor.

  19. The Onset Time of the Ownership Sensation in the Moving Rubber Hand Illusion

    Science.gov (United States)

    Kalckert, Andreas; Ehrsson, H. H.

    2017-01-01

    The rubber hand illusion (RHI) is a perceptual illusion whereby a model hand is perceived as part of one’s own body. This illusion has been extensively studied, but little is known about the temporal evolution of this perceptual phenomenon, i.e., how long it takes until participants start to experience ownership over the model hand. In the present study, we investigated a version of the rubber hand experiment based on finger movements and measured the average onset time in active and passive movement conditions. This comparison enabled us to further explore the possible role of intentions and motor control processes that are only present in the active movement condition. The results from a large group of healthy participants (n = 117) showed that the illusion of ownership took approximately 23 s to emerge (active: 22.8; passive: 23.2). The 90th percentile occurs in both conditions within approximately 50 s (active: 50; passive: 50.6); therefore, most participants experience the illusion within the first minute. We found indirect evidence of a facilitatory effect of active movements compared to passive movements, and we discuss these results in the context of our current understanding of the processes underlying the moving RHI. PMID:28344566

  20. A Narratological Study of Murakami Haruki’s Norwegian Wood and Sputnik Sweetheart – Time, Voice and Focalisation

    Directory of Open Access Journals (Sweden)

    Virginia Yeung

    2011-05-01

    Full Text Available This work analyses the narrative structure of two of Murakami Haruki’s (born 1949 most representative love stories: Norwegian Wood (1987 and Sputnik Sweetheart (1999. For the former work, I aim to illustrate how the author has constructed a narrative that creates strong emotional impact in the reader, by manipulating the temporal distance between the narrating and narrated ‘I.’ My discussion elucidates how the story is narrated in a way that mimics the flow of human memory. The part on Sputnik Sweetheart focuses on two aspects. First, the author’s experimentation with new narrative techniques, like a direct representation of the heroines’ consciousness, which is rare in his earlier novels. Second, my analysis of the tense pattern of the final scene shows that the author has added a chimeric effect to the story by destabilizing the temporal world in the story. I suggest that the inconclusive ending in both stories reflects and highlights the intricacy and incomprehensibility that is prone to exist in love relationships. In brief, this paper is a study that examines some significant features in the narrative techniques of Murakami Haruki, through a thorough analysis of the time structure, voice and focalization of two of his most popular stories.

  1. Tuning the Voices of a Choir: Detecting Ecological Gradients in Time-Series Populations.

    Science.gov (United States)

    Buras, Allan; van der Maaten-Theunissen, Marieke; van der Maaten, Ernst; Ahlgrimm, Svenja; Hermann, Philipp; Simard, Sonia; Heinrich, Ingo; Helle, Gerd; Unterseher, Martin; Schnittler, Martin; Eusemann, Pascal; Wilmking, Martin

    2016-01-01

    This paper introduces a new approach-the Principal Component Gradient Analysis (PCGA)-to detect ecological gradients in time-series populations, i.e. several time-series originating from different individuals of a population. Detection of ecological gradients is of particular importance when dealing with time-series from heterogeneous populations which express differing trends. PCGA makes use of polar coordinates of loadings from the first two axes obtained by principal component analysis (PCA) to define groups of similar trends. Based on the mean inter-series correlation (rbar) the gain of increasing a common underlying signal by PCGA groups is quantified using Monte Carlo Simulations. In terms of validation PCGA is compared to three other existing approaches. Focusing on dendrochronological examples, PCGA is shown to correctly determine population gradients and in particular cases to be advantageous over other considered methods. Furthermore, PCGA groups in each example allowed for enhancing the strength of a common underlying signal and comparably well as hierarchical cluster analysis. Our results indicate that PCGA potentially allows for a better understanding of mechanisms causing time-series population gradients as well as objectively enhancing the performance of climate transfer functions in dendroclimatology. While our examples highlight the relevance of PCGA to the field of dendrochronology, we believe that also other disciplines working with data of comparable structure may benefit from PCGA.

  2. Sharing Time and the Poetic Patterning of Caribbean Independence: The Narrative Architecture of Voice

    Science.gov (United States)

    Van der Aa, Jef

    2013-01-01

    This article discusses the narrative architecture and interactional uptake of a school child's story about independence in Barbados during sharing time. It is found that an institutional focus on standard resources impacts both teachers' and children's sociolinguistic behavior. Ethnopoetic analysis brings out the child's patterned use of narrative…

  3. Effects of capillary discharge current on the time of lasing onset of soft x-ray laser at low pressure

    Energy Technology Data Exchange (ETDEWEB)

    Zhao Yongpeng; Cheng Yuanli; Luan Bohan; Wu Yinchu; Wang Qi [National Key Laboratory of Tunable Laser Technology, Harbin Institute of Technology, 150001 Harbin (China)

    2006-01-21

    The laser spike of Ne-like argon 46.9 nm pumped by a capillary discharge is measured with an x-ray diode (XRD) at low Ar pressure (25 Pa). Changing the rise-time and amplitude of the main current, we observe the effects of current on the time of the laser spike. The experimental results show that the time of lasing onset, which is the time of the laser spike after the onset of the main current, is larger than 40 ns and almost constant when the rise-time and amplitude of the current are changed. The theoretical results are calculated with the snow-plough model and show that the plasma is pinched several times before the laser spike occurs.

  4. Manual muscle test at C5 palsy onset predicts the likelihood of and time to C5 palsy resolution.

    Science.gov (United States)

    Macki, Mohamed; Alam, Ridwan; Kerezoudis, Panagiotis; Gokaslan, Ziya; Bydon, Ali; Bydon, Mohamad

    2016-02-01

    The primary objective of this study was to identify time to and prognostic factors of C5 palsy resolution. All patients over a 7 year period who experienced C5 palsy following a posterior decompression and instrumented fusion surgery were retrospectively reviewed. C5 palsy resolution was defined as a recovery of deltoid muscle function equal to or greater than the preoperative condition as defined by the manual muscle test (MMT). Of the 511 patients who met the selection criteria, 8.6% (n=44) experienced C5 palsy. MMT information was available for 43 patients; 81.4% (n=35) had full resolution from their condition. Of the 35 patients who resolved, the median MMT score at onset was 3-. Following a discrete-time proportional hazards model, the hazards of C5 palsy resolution increased by 19% for every one-grade increase in MMT score at symptom onset (hazard ratio [HR]=1.19, p=0.005). Moreover, males displayed a 71% lower hazard of resolution than females (HR=0.29, p=0.003). Following an adjusted Kaplan-Meier analysis, the median time to C5 palsy resolution was between 6 months and 1 year. In a multiple linear regression, a lower MMT score at the onset of C5 palsy predicted a longer time to C5 palsy resolution (coefficient=-0.19, p=0.003). Time to C5 palsy onset was not statistically associated with hazards of palsy resolution (p=0.381) or time to resolution (p=0.121). A higher MMT score at the onset of C5 palsy statistically significantly predicted a higher chance of resolution and a shorter recovery time. Female sex was also associated with a higher hazard of resolution.

  5. Processing of voiced and unvoiced acoustic stimuli in musicians

    Directory of Open Access Journals (Sweden)

    Cyrill Guy Martin Ott

    2011-09-01

    Full Text Available Past research has shown that musical training induces changes in the processing of supra-segmental aspects of speech, such as pitch and prosody. The aim of the present study was to determine whether musical expertise also leads to an altered neurophysiological processing of sub-segmental information available in the speech signal, in particular the voice onset time (VOT. Using high-density EEG recordings we analysed the neurophysiological responses to voiced and unvoiced CV syllables and noise analogues in 26 German speaking adult musicians and non-musicians. From the EEG the N1 amplitude of the event-related potential (ERP and two microstates from the topographical EEG analysis (one around the N1 amplitude and one immediately preceding the N1 microstate were calculated to the different stimuli. Similar to earlier studies the N1 amplitude was different to voiced and unvoiced stimuli in non-musicians with larger amplitudes to voiced stimuli. The more refined microstate analysis revealed that the microstate within the N1 time window was shorter to unvoiced stimuli in non-musicians. For musicians there was no difference for the N1 amplitudes and the corresponding microstates between voiced and unvoiced stimuli. In addition, there was a longer very early microstate preceding the microstate at the N1 time window to non-speech stimuli only in musicians. Taken together, our findings suggest that musicians process unvoiced stimuli (irrespective whether these stimuli are speech or non-speech stimuli differently. We propose that musicians utilise the same network to analyse unvoiced stimuli as for the analysis of voiced stimuli. As a further explanation it is also possible that musicians devote more neurophysiological resources into the analysis of unvoiced segments.

  6. The timing of India-Asia collision onset - facts, theories, controversies

    Science.gov (United States)

    Hu, Xiumian; Garzanti, Eduardo; Wang, Jiangang; Huang, Wentao; An, Wei; Webb, Alex

    2016-04-01

    The timing of initial collision between India and Asia has remained grossly and windingly controversial for half a century. This paper attempts to review this crucial and hotly debated argument, describing first the different methods used to constrain the age of collision and discussing next the rationale, results, inferences and problems associated with each. We conclude that stratigraphy represents the best direct way to unravel collision chronology. Other methods focusing on the magmatic, metamorphic or paleomagnetic record provide additional fundamental constraints, but cannot provide a robust direct estimate of collision onset. Initial collision in the central-eastern Himalaya is dated directly at the Middle Paleocene (59±1 Ma) by the abrupt change in sediment provenance recorded in trench settings (Hu et al., 2015). The quasi-synchronous unconformities documented along both Tethyan passive margin of India and active margin of Asia from Tibet to Zanskar-Ladakh confirm that orogeny was underway at the close of the Paleocene (56 Ma) (Garzanti et al., 1987; Li et al., 2015; Hu et al., 2016), well before the disappearance of marine seaways in the Himalaya during the Eocene (50 Ma) (Najman et al., 2010). Sedimentary evolution and provenance changes in marine to fluvio-deltaic successions are recorded synchronously within error from the western to the central-eastern Himalaya, failing to provide evidence for diachronous collision. These coherent observations are hard to reconcile with three widely cited hypotheses invoking either earlier events of arc-continent collision or ophiolite obduction, or the protracted existence of a Greater India Basin, which should be all rejected after discussing the geological evidence. A scenario no more complex than the one involving solely the passive continental margin of India and the active continental margin of Asia is needed to explain the geological evolution of the nascent Himalaya. The collision between the Tethys

  7. Onset Time of Ischemic Events and Antiplatelet Therapy after Intracranial Stent-assisted Coil Embolization.

    Science.gov (United States)

    Matsumoto, Yoshihisa; Nakai, Kanji; Tsutsumi, Masanori; Iko, Minoru; Nii, Kouhei; Narita, Sumito; Eto, Ayumu; Mitsutake, Takahumi; Aikawa, Hiroshi; Kazekawa, Kiyoshi

    2014-04-01

    Stent-assisted coil embolization is effective for intracranial aneurysms, especially wide-necked aneurysms; however, the optimal antiplatelet regimens for ischemic events that develop after coil embolization have not yet been established. We aimed to determine the onset time of such postoperative ischemic events and the relationship between these events and antiplatelet therapy. We performed coil embolization using a vascular reconstruction stent for 43 cases of intracranial aneurysms and evaluated the incidence of postoperative ischemic events in these cases. Nine patients showed postoperative ischemic events during the follow-up period (13 ± 7 months). Two patients developed cerebral infarction within 24 hours. Five patients developed transient ischemic attack within 40 days while they were receiving dual antiplatelet therapy. In addition, 1 patient showed cerebral infarction 143 days postoperatively during single antiplatelet therapy, and a case of transient visual disturbance was reported 191 days postoperatively (49 days after antiplatelet therapy had been discontinued). We increased the number of antiplatelet agents in 4 of these patients. The other 5 patients were under strict observation with dual antiplatelet therapy. All these patients were shifted to single antiplatelet therapy 3-13 months postoperatively. No recurrence of ischemic events was noted. Postoperative ischemic events are most likely to occur within 40 days postoperatively. For patients with postoperative ischemic events, additional ischemic events can be prevented by increasing the number of antiplatelet agents; subsequently, they can be shifted to single antiplatelet therapy after the risk of recurrence has decreased. Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  8. The value of CMV IgG avidity and immunoblot for timing the onset of primary CMV infection in pregnancy.

    Science.gov (United States)

    Enders, Gisela; Daiminger, Anja; Bäder, Ursula; Exler, Simone; Schimpf, Yvonne; Enders, Martin

    2013-02-01

    Primary CMV infections in pregnancy are usually asymptomatic and only detected by serology. Estimating the onset of infection is a major diagnostic goal, since primary infections around conception and in early gestation hold a higher risk for congenital disease than those in later pregnancy. To assess the ability of serological supplementary CMV assays to date the onset of primary infection. From our routine diagnosis we identified 61 pregnant women (n=188 serum samples) with precisely determined onset of CMV primary infection either by IgG seroconversion (n=24) or by significant IgG antibody rise (n=37). One hundred and forty-seven sera were investigated using the VIDAS(®) CMV IgG avidity EIA (BioMèrieux) and 83 sera using the recomBlot CMV IgG with avidity (Mikrogen). Both assays proofed to be reliable in terms of timing the onset of CMV primary infection. An avidity index (AI) in the VIDAS avidity EIA of <40% indicated primary infection within the last 20 weeks (positive predictive value 93.4%; 99/106), whereas an intermediate AI excluded primary infection within the last 12 weeks (negative predictive value 88.2%; 15/17). The recomBlot showed high reliability (PPV 96.9%; 31/33) for timing the onset of infection within the last 14 weeks. Avidity testing by blot however could not be interpreted in 11 of 47 sera (23.4%). For timing the onset of infection (before or in early pregnancy) CMV avidity testing is most helpful if carried out within the first trimester up to the beginning of second trimester. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Class and subclass distribution of hantavirus-specific serum antibodies at different times after the onset of nephropathia epidemica.

    NARCIS (Netherlands)

    J. Groen (Jan); M.N. Gerding; J.G.M. Jordans; J.P.G. Clement; A.D.M.E. Osterhaus (Albert)

    1994-01-01

    textabstractSera from Dutch and Belgium individuals who suffered from nephropathia epidemica (NE), a mild form of haemorrhagic fever with renal syndrome (HFRS), were tested for the distribution of classes and subclasses of Hantavirus (HV)-specific antibodies at different times after the onset of the

  10. Time of onset in haemodialysis access-induced distal ischaemia (HAIDI) is related to the access type.

    NARCIS (Netherlands)

    Scheltinga, M.R.M.; Hoek, F. van; Bruijninckx, C.M.

    2009-01-01

    BACKGROUND: A small portion of haemodialysis patients develop hand ischaemia (HAIDI, haemodialysis access-induced distal ischaemia) in the presence of an arteriovenous access (AVA). It is unknown if the time of onset of ischaemia is related to the type of AVA. This review aims to investigate if a re

  11. Parametric time-to-onset models were developed to improve causality assessment of adverse drug reactions from antidiabetic drugs

    NARCIS (Netherlands)

    Scholl, Joep H G; van de Ven, Peter M; van Puijenbroek, Eugène P

    2015-01-01

    OBJECTIVES: The aim of this study was to investigate whether the time to onset (TTO) of common adverse drug reactions (ADRs) of antidiabetic drugs could be modeled using parametric distributions and whether these TTO distributions were dependent on patient characteristics. Furthermore, information r

  12. Evaluation of Analytical Modeling Functions for the Phonation Onset Process.

    Science.gov (United States)

    Petermann, Simon; Kniesburges, Stefan; Ziethe, Anke; Schützenberger, Anne; Döllinger, Michael

    2016-01-01

    The human voice originates from oscillations of the vocal folds in the larynx. The duration of the voice onset (VO), called the voice onset time (VOT), is currently under investigation as a clinical indicator for correct laryngeal functionality. Different analytical approaches for computing the VOT based on endoscopic imaging were compared to determine the most reliable method to quantify automatically the transient vocal fold oscillations during VO. Transnasal endoscopic imaging in combination with a high-speed camera (8000 fps) was applied to visualize the phonation onset process. Two different definitions of VO interval were investigated. Six analytical functions were tested that approximate the envelope of the filtered or unfiltered glottal area waveform (GAW) during phonation onset. A total of 126 recordings from nine healthy males and 210 recordings from 15 healthy females were evaluated. Three criteria were analyzed to determine the most appropriate computation approach: (1) reliability of the fit function for a correct approximation of VO; (2) consistency represented by the standard deviation of VOT; and (3) accuracy of the approximation of VO. The results suggest the computation of VOT by a fourth-order polynomial approximation in the interval between 32.2 and 67.8% of the saturation amplitude of the filtered GAW.

  13. Evaluation of Analytical Modeling Functions for the Phonation Onset Process

    Directory of Open Access Journals (Sweden)

    Simon Petermann

    2016-01-01

    Full Text Available The human voice originates from oscillations of the vocal folds in the larynx. The duration of the voice onset (VO, called the voice onset time (VOT, is currently under investigation as a clinical indicator for correct laryngeal functionality. Different analytical approaches for computing the VOT based on endoscopic imaging were compared to determine the most reliable method to quantify automatically the transient vocal fold oscillations during VO. Transnasal endoscopic imaging in combination with a high-speed camera (8000 fps was applied to visualize the phonation onset process. Two different definitions of VO interval were investigated. Six analytical functions were tested that approximate the envelope of the filtered or unfiltered glottal area waveform (GAW during phonation onset. A total of 126 recordings from nine healthy males and 210 recordings from 15 healthy females were evaluated. Three criteria were analyzed to determine the most appropriate computation approach: (1 reliability of the fit function for a correct approximation of VO; (2 consistency represented by the standard deviation of VOT; and (3 accuracy of the approximation of VO. The results suggest the computation of VOT by a fourth-order polynomial approximation in the interval between 32.2 and 67.8% of the saturation amplitude of the filtered GAW.

  14. Smoking onset and the time-varying effects of self-efficacy, environmental smoking, and smoking-specific parenting by using discrete-time survival analysis

    NARCIS (Netherlands)

    Hiemstra, J.M.; Otten, R.; Engels, R.C.M.E.

    2012-01-01

    This study examined the timing of smoking onset during mid- or late adolescence and the time-varying effects of refusal self-efficacy, parental and sibling smoking behavior, smoking behavior of friends and best friend, and parental smoking-specific communication. We used data from five annual waves

  15. Smoking onset and the time-varying effects of self-efficacy, environmental smoking, and smoking-specific parenting by using discrete-time survival analysis

    NARCIS (Netherlands)

    Hiemstra, J.M.; Otten, R.; Engels, R.C.M.E.

    2012-01-01

    This study examined the timing of smoking onset during mid- or late adolescence and the time-varying effects of refusal self-efficacy, parental and sibling smoking behavior, smoking behavior of friends and best friend, and parental smoking-specific communication. We used data from five annual waves

  16. Deaf-blindness: Voices of mothers concerning leisure-time physical activity and coping with disability

    Directory of Open Access Journals (Sweden)

    Dana Štěrbová

    2014-12-01

    Full Text Available Background: Deaf-blindness (DB is a distinct disability because of combined impairments of hearing and visual functions, causes severe difficulties in the psychosocial area, communication, social interaction, and interaction with the environment. Leisure-time physical activities (LTPA properly planned and executed can be beneficial in providing support and facilitating coping as strategy for managing stress in families of children with disabilities. Appropriate LTPA also influence the quality of the lives of people with DB. Our study was also based on coping theory. Objective: The purpose of this study was to examine the beliefs of mothers with regard to leisure-time physical activity of families of children with deaf-blindness, the benefits that activities can bring to families of children with DB, needs and the barriers to participation. Methods: Participants of this study were five mothers of children with DB, who were interviewed using the phenomenological tradition of qualitative inquiry. Results: Findings show six emergent themes in relation to perceived needs of children with DB: structure of life; coactive engagement; happiness and well-being; doing "normal things"; appropriate support and services; and appropriate communication. Conclusion: The results of the present study indicated that there are various support systems, which could facilitate participation in LTPA: (a special schools and respite care centers; (b special programs such as family camps or programs where children can learn basic skills needed for participation in physical activities (e.g., swimming or biking; (c adapted equipment which can allow participation; (d parental support groups where parents can share common experiences or religious support groups, which might be able to accept a family with a child with DB as equal member of their community; and finally (e assistance, which could have a formal form of professionals or paraprofessionals working with persons with

  17. Time of erythema onset after application of methyl nicotinate ointments as response parameter: influence of penetration kinetics and enhancing agents.

    Science.gov (United States)

    Remane, Y; Leopold, C S

    2006-01-01

    The time of erythema onset may be used as a response parameter for quantification of the cutaneous erythema response induced by methyl nicotinate. The vehicles light mineral oil (LMO; test) and medium chain triglycerides (MCT; standard) were compared with regard to the pharmacodynamic response. Moreover, the influence of penetration enhancers on the time of erythema onset was investigated under zero order penetration kinetics. The enhancers dimethyl sulfoxide, diethylene glycol monoethyl ether and three different glycerides in different concentrations were added to MCT as a standard vehicle. All preparations were applied to the forearms of volunteers under infinite dose conditions at different thermodynamic drug activity levels (0.2-3.2% of the saturation level) and different drug concentrations (0.051-0.816%), respectively. Different penetration kinetics do not influence data of erythema onset, as these data are comparable to those obtained under finite dose conditions (first order penetration kinetics). With regard to the penetration enhancers, a significantly enhanced penetration of methyl nicotinate could be observed only for diethylene glycol monoethyl ether and dimethyl sulfoxide. However, no significant difference between light mineral oil and MCT could be found with regard to penetration enhancement. The time of erythema onset is an easy and efficient parameter for quantification of the pharmacodynamic response caused by nicotinates.

  18. Onset of intractability and its course over time : The Dutch study of epilepsy in childhood

    NARCIS (Netherlands)

    Geerts, Ada; Brouwer, Oebele; Stroink, Hans; van Donselaar, Cees; Peters, Boudewijn; Peeters, Els; Arts, Willem F.

    2012-01-01

    Purpose: Intractability in epilepsy is difficult to define, and little is known about its onset, course, and duration. We investigated these aspects (as well as the occurrence of intractability) during long-term follow-up in patients with epilepsy, focusing on possible explanations for the variation

  19. Finding a Voice

    Science.gov (United States)

    Stuart, Shannon

    2012-01-01

    Schools have struggled for decades to provide expensive augmentative and alternative communication (AAC) resources for autistic students with communication challenges. Clunky voice output devices, often included in students' individualized education plans, cost about $8,000, a difficult expense to cover in hard times. However, mobile technology is…

  20. Monitoring of 1-min personal particulate matter exposures in relation to voice-recorded time-activity data.

    Science.gov (United States)

    Quintana, P J; Valenzia, J R; Delfino, R J; Liu, L J

    2001-12-01

    Recent studies on the association between exposures to airborne particulate matter (PM) and disease have identified short-term peaks in PM exposures as posing especial health threats. Lightweight personal instruments are needed to characterize short-term exposures to PM and to identify the most important sources of high PM excursions. In this study, we measured exposure to fine PM using a small personal nephelometer (pDR; MIE, Inc) to investigate the utility of this instrument in identifying activities and microenvironments most associated with high PM exposures and the magnitude and duration of peaks in PM exposures. Ten adult volunteers wore a pDR recording PM concentrations at 1-min time intervals for 1 week each. PM concentrations were measured by the pDR in units of microg/m(3) based on light scatter. The use of a time-stamped voice recorder enabled activity and location to be continuously documented in real time. In addition, a small, inexpensive light intensity logger was affixed to the pDR to evaluate the potential of this instrument to assist in verifying wearer- recorded data. For each person, patterns of PM exposure were remarkably consistent over daily activities and showed large excursions associated with specific indoor and outdoor microenvironments and activities, such as cooking. When the magnitude and duration of excursions in PM were analyzed, we found that high PM levels occurred in relatively few of the minutes measured but comprised a substantial fraction of the total exposure to PM. Fifteen-minute averaged PM levels were found to be as much as 10 times the daily average. When the data were analyzed with a generalized estimating equation model to account for effects of autocorrelation and clustering, PM exposure was significantly higher during subject-reported events including barbeque, yard work, being near pets or construction activities, cooking, and environmental tobacco smoke exposure, as compared with periods with no pollution events

  1. A real-time study of plosives in Glaswegian using an automatic measurement algorithm: change or age-grading?

    OpenAIRE

    Stuart-Smith, J.; Rathcke, T.; Sonderegger, M.; Macdonald, R.

    2015-01-01

    This paper presents a collaborative study of variation and potential change in the voicing contrast in Scottish English plosives, analyzed in recordings from twelve vernacular female speakers of different generations made in the 1970s and the 2000s in Glasgow. We adapted an existing automatic measurement algorithm for predicting Voice Onset Time (VOT) originally developed for voiceless stops, for the analysis of voiced and voiceless plosives in casual sociolinguistic speech recordings of diff...

  2. The seasonal timing of warming that controls onset of the growing season.

    Science.gov (United States)

    Clark, James S; Melillo, Jerry; Mohan, Jacqueline; Salk, Carl

    2014-04-01

    Forecasting how global warming will affect onset of the growing season is essential for predicting terrestrial productivity, but suffers from conflicting evidence. We show that accurate estimates require ways to connect discrete observations of changing tree status (e.g., pre- vs. post budbreak) with continuous responses to fluctuating temperatures. By coherently synthesizing discrete observations with continuous responses to temperature variation, we accurately quantify how increasing temperature variation accelerates onset of growth. Application to warming experiments at two latitudes demonstrates that maximum responses to warming are concentrated in late winter, weeks ahead of the main budbreak period. Given that warming will not occur uniformly over the year, knowledge of when temperature variation has the most impact can guide prediction. Responses are large and heterogeneous, yet predictable. The approach has immediate application to forecasting effects of warming on growing season length, requiring only information that is readily available from weather stations and generated in climate models. © 2013 John Wiley & Sons Ltd.

  3. Facing the times: A young onset dementia support group: Facebook™ style.

    Science.gov (United States)

    Craig, Denise; Strivens, Edward

    2016-03-01

    Young onset dementia accounts for up to 1 in 10 dementia diagnoses. Those diagnosed face premature transition into the realm of aged care services and adjustment to an illness of ageing prior to age 65. To help elicit communication of the perceived psychosocial needs of this group, provide a platform to gain peer support and advocate for increased awareness, the Young Onset Dementia Support Group was established on the social networking site, Facebook™ . Followers post comments, read educational or otherwise interesting news feeds, share inspirational quotes and access others living with dementia worldwide. Facebook provides a means of rapid global reach in a way that allows people with dementia to increase their communications and potentially reduce isolation. This paper was authored by the page administrators. We aim to highlight the promising utility of a social network platform just entering its stride amongst health communication initiatives.

  4. Fixed-time post-cervical artificial insemination in sows receiving porcine luteinising hormone at oestrus onset.

    Science.gov (United States)

    Fontana, D L; Ulguim, R R; Sbardella, P E; Bernardi, M L; Wentz, I; Bortolozzo, F P

    2014-01-30

    Fixed-time post-cervical artificial insemination (FTPCAI) allows a wider use of high indexing boars and a considerable reduction in labour requirements in swine production. The aim of this study was to evaluate fixed-time artificial insemination (FTAI) efficiency using different artificial insemination protocols and porcine luteinising hormone (pLH) to induce ovulation. A total of 597 weaned sows in which oestrus detection was performed once daily (08:00 am) was allocated to three groups: FTPCAI1 (n=199) - sows received a 5-mg (4 ml) intramuscular injection of pLH at oestrus onset, and were inseminated 24h later; FTPCAI2 (n=199) - sows received 5mg of pLH and were inseminated at oestrus onset (0 h) and 24h after; and MultPCAI (n=199) - sows did not receive pLH, and the first AI was performed at oestrus onset (0 h) and repeated every 24h during oestrus. Homospermic doses (1.5 × 10(9) total sperm cells/50 ml) were used in post-cervical artificial insemination (PCAI) in all the treatments. Hormonal treatment did not affect (P>0.05) the interval between oestrus onset and ovulation (overall 32.4h) and there were no differences (P>0.05) in farrowing rate (overall 91.6%) or litter size (overall 12.6 piglets born) among treatments. In sows treated with pLH at oestrus onset, a single PCAI with 1.5 billion sperm cells did not compromise reproductive performance compared with a double PCAI at 24h intervals.

  5. Differences in onset time between the vastus medialis and lateralis during stair stepping in individuals with genu varum or valgum.

    Science.gov (United States)

    Park, Seol; Chung, Jun-Sub; Kong, Yong-Soo; Ko, Yu-Min; Park, Ji-Won

    2015-09-01

    [Purpose] We investigated the difference in onset time between the vastus medialis and lateralis according to knee alignment during stair ascent and descent to examine the effects of knee alignment on the quadriceps during stair stepping. [Subjects] Fifty-two adults (20 with genu varum, 12 with genu valgum, and 20 controls) were enrolled. Subjects with > 4 cm between the medial epicondyles of the knees were placed in the genu varum group, whereas subjects with > 4 cm between the medial malleolus of the ankle were placed in the genu valgum group. [Methods] Surface electromyography was used to measure the onset times of the vastus medialis and vastus lateralis during stair ascent and descent. [Results] The vastus lateralis showed more delayed firing than the vastus medialis in the genu varum group, whereas vastus medialis firing was more delayed than vastus lateralis firing in the genu valgum group. Significant differences in onset time were detected between stair ascent and descent in the genu varum and valgum groups. [Conclusion] Genu varum and valgum affect quadriceps firing during stair stepping. Therefore, selective rehabilitation training of the quadriceps femoris should be considered to prevent pain or knee malalignment deformities.

  6. Vision-based Detection of Acoustic Timed Events: a Case Study on Clarinet Note Onsets

    Science.gov (United States)

    Bazzica, A.; van Gemert, J. C.; Liem, C. C. S.; Hanjalic, A.

    2017-05-01

    Acoustic events often have a visual counterpart. Knowledge of visual information can aid the understanding of complex auditory scenes, even when only a stereo mixdown is available in the audio domain, \\eg identifying which musicians are playing in large musical ensembles. In this paper, we consider a vision-based approach to note onset detection. As a case study we focus on challenging, real-world clarinetist videos and carry out preliminary experiments on a 3D convolutional neural network based on multiple streams and purposely avoiding temporal pooling. We release an audiovisual dataset with 4.5 hours of clarinetist videos together with cleaned annotations which include about 36,000 onsets and the coordinates for a number of salient points and regions of interest. By performing several training trials on our dataset, we learned that the problem is challenging. We found that the CNN model is highly sensitive to the optimization algorithm and hyper-parameters, and that treating the problem as binary classification may prevent the joint optimization of precision and recall. To encourage further research, we publicly share our dataset, annotations and all models and detail which issues we came across during our preliminary experiments.

  7. Histologic differences in placentas of preeclamptic/eclamptic gestations by birthweight, placental weight, and time of onset.

    Science.gov (United States)

    Stark, Matthew W; Clark, Latoya; Craver, Randall D

    2014-01-01

    With preeclampsia/eclampsia (PE/E), infants more often are either large or small for gestational age. We explored whether the differences in infant birthweight (BW), placental weights (PW), or time of onset are associated with histologic features of maternal vascular underperfusion. A retrospective chart identified 243 PE/E gestations between 2007 and 2010. Gestational age only was known at slide review. Investigated features included increased syncytial knots, villous agglutination, increased intervillous fibrin, distal villous hypoplasia, acute atherosis, mural hypertrophy of membrane arterioles, muscularized basal plate arteries, increased placental site giant cells, increased immature intermediate trophoblasts, infarcts, and villitis. The results were correlated with BW, PW, and onset time PE/E. One hundred thirty-eight PE/E gestations were identified with adequate slides and history. Increased BW placentas had decreased syncytial knots and increased mural hypertrophy of membrane arterioles. Decreased BW had increased placenta site giant cells. Increased PW had decreased distal villous hypoplasia. Decreased PW had increased syncytial knots, increased intervillous fibrin, and increased acute atherosis. Early-onset disease had increased syncytial knots, distal villous hypoplasia, villous agglutination, and infarcts. This suggests PE/E is not a single process resulting in a uniform distribution of lesions but, rather, is composed of several different processes manifesting a single clinical presentation.

  8. 移动机器人实时语音控制的实现%Realization on the real-time voice control system for mobile robot

    Institute of Scientific and Technical Information of China (English)

    高美娟; 杨智鑫; 田景文

    2011-01-01

    Based on the study of speech recognition algorithms, the real-time voice control system for mobile robot has been designed and realized. Dynamic Time warping (DTW) algorithm was chosen for this system, and the programming has been finished with VC platform. To ensure the real-time property of the system, the automatic record system with voice switch was designed. The experiment confirmed that this system shows good effect in real-time speech control%通过对语音识别过程的研究,设计并制作开发了1套基于移动机器人的实时语音控制系统.采用了动态时间规整(DTW)算法作为核心识别方法,并使用VC完成了对各部分的软件编程.其中为了保证系统的实时性,特别设计了带有声控开关的自动录音系统.通过最后的实验证实了,系统可以很好的完成实时语音控制.

  9. Familiarity and Voice Representation: From Acoustic-Based Representation to Voice Averages

    Directory of Open Access Journals (Sweden)

    Maureen Fontaine

    2017-07-01

    Full Text Available The ability to recognize an individual from their voice is a widespread ability with a long evolutionary history. Yet, the perceptual representation of familiar voices is ill-defined. In two experiments, we explored the neuropsychological processes involved in the perception of voice identity. We specifically explored the hypothesis that familiar voices (trained-to-familiar (Experiment 1, and famous voices (Experiment 2 are represented as a whole complex pattern, well approximated by the average of multiple utterances produced by a single speaker. In experiment 1, participants learned three voices over several sessions, and performed a three-alternative forced-choice identification task on original voice samples and several “speaker averages,” created by morphing across varying numbers of different vowels (e.g., [a] and [i] produced by the same speaker. In experiment 2, the same participants performed the same task on voice samples produced by familiar speakers. The two experiments showed that for famous voices, but not for trained-to-familiar voices, identification performance increased and response times decreased as a function of the number of utterances in the averages. This study sheds light on the perceptual representation of familiar voices, and demonstrates the power of average in recognizing familiar voices. The speaker average captures the unique characteristics of a speaker, and thus retains the information essential for recognition; it acts as a prototype of the speaker.

  10. Hatching time and alevin growth prior to the onset of exogenous feeding in farmed, wild and hybrid Norwegian Atlantic salmon.

    Directory of Open Access Journals (Sweden)

    Monica Favnebøe Solberg

    Full Text Available The onset of exogenous feeding, when juveniles emerge from the gravel, is a critical event for salmonids where early emergence and large size provide a competitive advantage in the wild. Studying 131 farmed, hybrid and wild Norwegian Atlantic salmon families, originating from four wild populations and two commercial strains, we investigated whether approximately 10 generations of selection for faster growth has also resulted in increased somatic growth prior to the onset of exogenous feeding. In addition, we tested whether relaxed selection in farms has allowed for alterations in hatching time between farmed and wild salmon. Across three cohorts, wild salmon families hatched earlier than farmed salmon families, while hybrid families displayed intermediate hatching times. While the observed differences were small, i.e., 1-15 degree-days (0-3 days, as water temperatures were c. 5-6°C, these data suggest additive genetic variation for hatching time. Alevin length prior to exogenous feeding was positively related to egg size. After removal of egg size effects, no systematic differences in alevin length were observed between the wild and farmed salmon families. While these results indicate additive genetic variation for egg development timing, and wild salmon families consistently hatched earlier than farmed salmon families, these differences were so small they are unlikely to significantly influence early life history competition of farmed and wild salmon in the natural environment. This is especially the case given that the timing of spawning among females can vary by several weeks in some rivers. The general lack of difference in size between farmed and wild alevins, strongly suggest that the documented differences in somatic growth rate between wild and farmed Norwegian Atlantic salmon under hatchery conditions are first detectable after the onset of exogenous feeding.

  11. Estimating time to onset of swine influenza symptoms after initial novel A(H1N1v) viral infection.

    Science.gov (United States)

    Tom, B D M; Van Hoek, A J; Pebody, R; McMenamin, J; Robertson, C; Catchpole, M; De Angelis, D

    2011-09-01

    Characterization of the incubation time from infection to onset is important for understanding the natural history of infectious diseases. Attempts to estimate the incubation time distribution for novel A(H1N1v) have been, up to now, based on limited data or peculiar samples. We characterized this distribution for a generic group of symptomatic cases using laboratory-confirmed swine influenza case-information. Estimates of the incubation distribution for the pandemic influenza were derived through parametric time-to-event analyses of data on onset of symptoms and exposure dates, accounting for interval censoring. We estimated a mean of about 1·6-1·7 days with a standard deviation of 2 days for the incubation time distribution in those who became symptomatic after infection with the A(H1N1v) virus strain. Separate analyses for the <15 years and ≥ 15 years age groups showed a significant (P<0·02) difference with a longer mean incubation time in the older age group.

  12. French native speakers in the making: from language-general to language-specific voicing boundaries.

    Science.gov (United States)

    Hoonhorst, Ingrid; Colin, Cécile; Markessis, Emily; Radeau, Monique; Deltenre, Paul; Serniclaes, Willy

    2009-12-01

    By examining voice onset time (VOT) discrimination in 4- and 8-month-olds raised in a French-speaking environment, the current study addresses the question of the role played by linguistic experience in the reshaping of the initial perceptual abilities. Results showed that the language-general -30- and +30-ms VOT boundaries are better discriminated than the 0-ms boundary in 4-month-olds, whereas 8-month-olds better discriminate the 0-ms boundary. These data support explanations of speech development stressing the effects of both language-general boundaries and linguistic environment (attunement theory and coupling theory). Results also suggest that the acquisition of the adult voicing boundary (at 0 ms VOT in French vs. +30 ms VOT in English) is faster and more linear in French than in English. This latter aspect of the results might be related to differences in the consistency of VOT distributions of voiced and voiceless stops between languages.

  13. Biomechanical models of damage and healing processes for voice health

    DEFF Research Database (Denmark)

    Granados Corsellas, Alba; Brunskog, Jonas; Jacobsen, Finn

    2013-01-01

    In voice-loading occupations employees are required to use their voice for continuous and large periods of time, which might lead to voice problems. In this work anomalous vocal-fold vibrations due to long-time high voice-load are investigated. Laryngeal endoscopic high-speed images within...... the vocal-fold plane are available. This data is used to improve existing continuum biomechanical models of the vocal-folds by analyzing the injury processes. The project is expected to result in methods that objectively demonstrate the impact of high voice-load on voice. A detailed description...

  14. Timing of the onset of MIS 11 revealed by speleothem in southern Europe

    Science.gov (United States)

    Hu, Hsun-Ming; Shen, Chuan-Chou; Michel, Véronique; Kano, Akihiro

    2017-04-01

    The interglacial period, known as Marine Isotope Stage 11 (MIS 11, 428-397 thousand years ago), is often considered as a potential analogue for future climate projection because of the similar patterns of insolation variability. However, studies on mechanisms of the onset of MIS 11 (called Termination V, T-V) in response to insolation increase is still hampered by a lack of good dating materials in paleoclimate archives, despite a stack of East Asian monsoon records with precise U-Th dates has been proposed. Previous studies suggested the δ18O value registered in speleothems in Mediterranean realm can be a good bridge connecting the U-Th-based age model of speleothem to marine cores from Mediterranean sea, which opens a new possibility to detect ocean-atmosphere/internal-external forcing interaction beyond 14C dating limitation. Here we present a new speleothem δ18O record from northern Italy covering 500-300 thousand years ago. The results show a similar pattern with δ18O records of marine cores around Mediterranean. The age model of the speleothem hence provides an opportunity for tuning the marine cores, which could improve our understanding of relationship between global atmosphere and ocean circulations.

  15. Voice Collection under Different Spectrum

    Directory of Open Access Journals (Sweden)

    Min Li

    2013-05-01

    Full Text Available According to the short-time Fourier transform theory and principle of digital filtering, this paper established a mathematical model called collection of voice signal collection at different spectrum. The voice signal was a non-stationary process, while the standard Fourier transform only applied to the periodic signal, transient signals or stationary random signal. Therefore, the standard Fourier transform could not be directly used for the speech signal. By controlling the input different types and parameters, this paper analyzed the collected original voice signal spectrum with the use of MATLAB software platform. At the same time, it realized the extraction, recording and playback of the speech signal at different frequencies. Therefore, the waveforms could be displayed obviously on the graphic user interface and voice effect could be more clearly. Meanwhile, the result was verified by the hardware platforms, which consisted of TMS320VC5509A [1] chip and TLV320AIC23 voice chip. The results showed that the extraction of voice signal under different spectrum model was scientific, rational and effective.

  16. Use of porcine luteinizing hormone at oestrous onset in a protocol for fixed-time artificial insemination in gilts.

    Science.gov (United States)

    Ulguim, R R; Fontana, D L; Rampi, J Z; Bernardi, M L; Wentz, I; Bortolozzo, F P

    2014-10-01

    The aim of this study was to evaluate the effect of porcine luteinizing hormone (pLH) given at oestrous onset in gilts, by different routes and doses, on the interval between onset of oestrus and ovulation (IOEO) and reproductive performance using a single fixed-time artificial insemination (FTAI). A total of 153 gilts were submitted to oestrous detection at 8-h intervals and assigned to three groups: control - without hormone application and inseminated at 0, 24 and 48 h after oestrous onset; VS2.5FTAI - 2.5 mg pLH by the vulvar submucosal route at oestrous onset and a single FTAI 16 h later; IM5FTAI - 5 mg pLH by the intramuscular route at oestrous onset and a single FTAI 16 h later. More VS2.5FTAI gilts (47.1%; p  0.05). The IOEO tended to be shorter (p = 0.06) in VS2.5FTAI (30.2 ± 1.4 h) than in control (34.7 ± 1.4 h) gilts, but there was no difference (p > 0.05) between control and IM5FTAI (32.8 ± 1.4 h) gilts. Farrowing rate was not different (p > 0.05) among treatments. Total born piglets (TB) was lower (p < 0.05) in VS2.5FTAI (12.3 ± 0.4) than in control gilts (14.1 ± 0.4), whereas intermediate TB was observed in IM5FTAI gilts (13.3 ± 0.4). Due to the advancement of ovulation, reduction of the hormonal dose and the ease of application, the vulvar submucosal route would be the best option for FTAI protocols, but their negative impact on litter size remains to be elucidated. Taking into account the good fertility results obtained in IM5FTAI gilts whose ovulation was not advanced, the possibility of a single FTAI without any hormonal treatment should be further investigated, to establish reliable FTAI protocols for gilts.

  17. Determination of the onset time in polarization power ratio Z/H for precursor of Sumatra earthquake

    Energy Technology Data Exchange (ETDEWEB)

    Ahadi, S., E-mail: su4idi@yahoo.com [Faculty of Earth Sciences and Technology, Bandung Institute of Technology, Jl. Ganesha No.10, Bandung 40132 (Indonesia); Puspito, N. T.; Ibrahim, G. [Faculty of Mining and Petroleum Engineering, Bandung Institute of Technology, Jl. Ganesha No.10 Bandung 40132 (Indonesia); Saroso, S. [National Institute of Aeronautic and Space (LAPAN), Jl. Djunjunan No. 133, Bandung 40173 (Indonesia)

    2014-09-25

    Determination of onset time precursors of strong earthquakes (Mw > 5) and distance (d < 500 km) using geomagnetic data from Geomagnetic station KTB, Sumatra and two station references DAV, Philippine and DAW, Australia. separate techniques are required in its determination. Not the same as that recorded in the kinetic wave seismograms can be determined by direct time domain. Difficulties associated with electromagnetic waves seismogenic activities require analysis of the transformed signal in the frequency domain. Determination of the frequency spectrum will determine the frequency of emissions emitted from the earthquake source. The aim is to analyze the power amplitude of the ULF emissions in the horizontal component (H) and vertical component (Z). Polarization power ratio Z/H is used for determining the sign of earthquake precursors controlled by the standard deviation. The pattern recognition polarization ratio should be obtained which can differentiate emissions from seismogenic effects of geomagnetic activity. ULF emission patterns generated that seismogenic effect has duration > 5 days and the dominance of emission intensity recorded at the Z component and for the dominance of the emission intensity of geomagnetic activity recorded in the component H. The result shows that the onset time is determined when the polarization power ratio Z/H standard deviation over the limit (p ± 2 σ) which has a duration of > 5 days.

  18. Cerebral activity to opposite-sex voices reflected by event-related potentials.

    Directory of Open Access Journals (Sweden)

    Ya Li

    Full Text Available Human voice is a gender discriminating cue and is important to mate selection. This study employed electrophysiological recordings to examine whether there is specific cerebral activity when presented with opposite-sex voices as compared to same-sex voices. Male voices and female voices were pseudo-randomly presented to male and female participants. In Experiment 1, participants were instructed to determine the gender of each voice. A late positivity (LP response around 750 ms after voice onset was elicited by opposite-sex voices, as reflected by a positive deflection of the ERP to opposite-sex voices than that to same-sex voices. This LP response was prominent around parieto-occipital recording sites, and it suggests an opposite-sex specific process, which may reflect emotion- and/or reward-related cerebral activity. In Experiment 2, participants were instructed to press a key when hearing a non-voice pure tone and not give any response when they heard voice stimuli. In this task, no difference were found between the ERP to same-sex voices and that to opposite-sex voices, suggesting that the cerebral activity to opposite-sex voices may disappear without gender-related attention. These results provide significant implications on cognitive mechanisms with regard to opposite-sex specific voice processing.

  19. Time of symptom onset and value of myocardial blush and infarct size on prognosis in patients with ST-elevation myocardial infarction.

    Science.gov (United States)

    Wieringa, Wouter G; Lexis, Chris P H; Mahmoud, Karim D; Ottervanger, Jan Paul; Burgerhof, Johannes G M; Pundziute, Gabija; van 't Hof, Arnoud W J; van Gilst, Wiek H; Lipsic, Erik

    2014-07-01

    In patients with ST-segment elevation myocardial infarction (STEMI), the time of onset of ischemia has been associated with myocardial infarction (MI) size. Myocardial blush grade (MBG) reflects myocardial response to ischemia/reperfusion injury, which may differ according to time of the day. The aim of our study was to explore the 24-hour variation in MBG and MI size in relation to outcomes in STEMI patients. A retrospective multicenter analysis of 6970 STEMI patients was performed. Time of onset of STEMI was divided into four 6-hour periods. STEMI patients have a significant 24-hour pattern in onset of symptoms, with peak onset around 09:00 hour. Ischemic time was longest and MI size, estimated by peak creatine kinase concentration, was largest in patients with STEMI onset between 00:00 and 06:00 hours. Both MBG and MI size were independently associated with mortality. Time of onset of STEMI was not independently associated with mortality when corrected for baseline and procedural factors. Interestingly, patients presenting with low MBG between 00:00 and 06:00 hours had a better prognosis compared to other groups. In conclusion, patients with symptom onset between 00:00 and 06:00 hours have longer ischemic time and consequently larger MI size. However, this does not translate into a higher mortality in this group. In addition, patients with failed reperfusion presenting in the early morning hours have better prognosis, suggesting a 24-hour pattern in myocardial protection.

  20. Speaking and Nonspeaking Voice Professionals: Who Has the Better Voice?

    Science.gov (United States)

    Chitguppi, Chandala; Raj, Anoop; Meher, Ravi; Rathore, P K

    2017-04-18

    Voice professionals can be classified into two major subgroups: the primarily speaking and the primarily nonspeaking voice professionals. Nonspeaking voice professionals mainly include singers, whereas speaking voice professionals include the rest of the voice professionals. Although both of these groups have high vocal demands, it is currently unknown whether both groups show similar voice changes after their daily voice use. Comparison of these two subgroups of voice professionals has never been done before. This study aimed to compare the speaking voice of speaking and nonspeaking voice professionals with no obvious vocal fold pathology or voice-related complaints on the day of assessment. After obtaining relevant voice-related history, voice analysis and videostroboscopy were performed in 50 speaking and 50 nonspeaking voice professionals. Speaking voice professionals showed significantly higher incidence of voice-related complaints as compared with nonspeaking voice professionals. Voice analysis revealed that most acoustic parameters including fundamental frequency, jitter percent, and harmonic-to-noise ratio were significantly higher in speaking voice professionals, whereas videostroboscopy did not show any significant difference between the two groups. This is the first study of its kind to analyze the effect of daily voice use in the two subgroups of voice professionals with no obvious vocal fold pathology. We conclude that voice professionals should not be considered as a homogeneous group. The detrimental effects of excessive voice use were observed to occur more significantly in speaking voice professionals than in nonspeaking voice professionals. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  1. Leveraging voice

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2017-01-01

    researchers improve our practices and how could digital online video help offer more positive stories about research and higher education? How can academics in higher education be better to tell about our research, thereby reclaiming and leveraging our voice in a post-factual era? As higher education......This paper speculates on how researchers share research without diluting our credibility and how to make strategies for the future. It also calls for consideration of new traditions and practices for communicating knowledge to a wider audience across multiple media platforms. How might we...... continues to engage with digital and networked technologies it becomes increasingly relevant to question why and how academics could (re) position research knowledge in the digital and online media landscape of today and the future. The paper highlights methodological issues that arise in relation...

  2. Feeling voices.

    Directory of Open Access Journals (Sweden)

    Paolo Ammirante

    Full Text Available Two experiments investigated deaf individuals' ability to discriminate between same-sex talkers based on vibrotactile stimulation alone. Nineteen participants made same/different judgments on pairs of utterances presented to the lower back through voice coils embedded in a conforming chair. Discrimination of stimuli matched for F0, duration, and perceived magnitude was successful for pairs of spoken sentences in Experiment 1 (median percent correct = 83% and pairs of vowel utterances in Experiment 2 (median percent correct = 75%. Greater difference in spectral tilt between "different" pairs strongly predicted their discriminability in both experiments. The current findings support the hypothesis that discrimination of complex vibrotactile stimuli involves the cortical integration of spectral information filtered through frequency-tuned skin receptors.

  3. Effects of L1 prosody on segmental contrast in L2: The case of English stop voicing contrast produced by Korean speakers.

    Science.gov (United States)

    Choi, Jiyoun; Kim, Sahyang; Cho, Taehong

    2016-03-01

    This study investigated how the L1 phonetics-prosody interface transfers to L2 by examining prosodic strengthening effects (due to prosodic position and focus) on English voicing contrast (bad-pad) as produced by Korean vs English speakers. Under prosodic strengthening, Korean speakers showed a greater F0 difference due to voicing than English speakers, suggesting that their experience with the macroprosodic use of F0 in Korean transfers into L2. Furthermore, Korean speakers produced voiced stops with low F0 and short voice onset time as English speakers did, although such a cue pairing is absent in Korean, showing dissociation of cues from L1 segments for L2 production.

  4. Longitudinal observations of typical English voicing acquisition in a 2-year-old child: Stability of the contrast and considerations for clinical assessment.

    Science.gov (United States)

    Hitchcock, Elaine R; Koenig, Laura L

    2015-01-01

    Early assessment of phonetic and phonological development requires knowledge of typical versus atypical speech patterns, as well as the range of individual developmental trajectories. The nature of data reporting in previous literature on typical voicing acquisition left aspects of the developmental process unclear and limited clinical applicability. This work extends a previous four-month group study to present data for one child over 12 months. Words containing initial /b p d t/ were elicited from a monolingual English-speaking 2-year-old child biweekly for 25 sessions. Voice onset time (VOT) was measured for each stop. For each consonant and recording session, we measured range as well as accuracy, overshoot and discreteness calculated for means and individual tokens. The results underscore the value of token-by-token analyses. They further reveal that typical development may involve an extended period of fluctuating voicing patterns, suggesting that the voiced/voiceless contrast may take months or years to stabilise.

  5. Time linkages between pollination onsets of different taxa in Perugia, Central Italy--an update.

    Science.gov (United States)

    Frenguelli, Giuseppe; Ghitarrini, Sofia; Tedeschini, Emma

    2016-01-01

    In the last decades, increasing attention has been paid to pollinosis. Numerous studies have been carried out concerning the pollination timing of allergenic plant species and the possibility to forecast its beginning and intensity using several statistical methods and models. This study proposes a simple and fast method to identify in advance the time lapse in which the pollination of some allergenic taxa should start. The times of pollination of 14 taxa were recorded in the area of Perugia (Central Italy) by means of a 7-volumetric Hirst-Type pollen trap. For a 30-year period (1984-2013), annual starting dates were calculated for each taxa, using the 5% method (Lejoly-Gabriel). The time linkages between these starting dates were then estimated, considering them in pairs and calculating linear regression coefficients. For the significantly linked species, forecasting models were obtained by means of linear regression analysis. To apply these models to the ongoing pollen season, pollination beginning of the earlier species has to be calculated using a sum-based method. From this date, through the obtained equations, it is possible to predict the approximate period in which the pollination of the second linked taxa should start. The possibility to predict the start of the pollen season of these taxa could be of great importance from the allergological point of view. In fact, an early or delayed flowering can have considerable effects in the prophylaxis programming and efficacy.

  6. Time From Symptom Onset to Treatment and Outcomes after Thrombolytic Therapy

    NARCIS (Netherlands)

    L.K. Newby (Kristin); W.R. Rutsch (Wolfgang); R.M. Califf (Robert); M.L. Simoons (Maarten); P.E. Aylward (Philip Edmund); P.W. Armstrong (Paul); L.H. Woodlief (Lynn); K.L. Lee (Kerry); E.J. Topol (Eric); F.J.J. van de Werf (Frans)

    1996-01-01

    textabstractOBJECTIVES: This study sought to examine the relations among patient characteristics, time to thrombolysis and outcomes in the international GUSTO-I trial. BACKGROUND: Studies have shown better left ventricular function and decreased infarct size as well as increased survival with earlie

  7. Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA.

    Science.gov (United States)

    Grondin, Richard; Ge, Pei; Chen, Qingmin; Sutherland, Jessica E; Zhang, Zhiming; Gash, Don M; Stiles, David K; Stewart, Gregory R; Sah, Dinah W Y; Kaemmerer, William F

    2015-06-30

    One possible treatment for Huntington's disease involves direct infusion of a small, interfering RNA (siRNA) designed to reduce huntingtin expression into brain tissue from a chronically implanted programmable pump. Here, we studied the suppression of huntingtin mRNA achievable with short infusion times, and investigated how long suppression may persist after infusion ceases. Rhesus monkeys received 3 days of infusion of Magnevist into the putamen to confirm catheter patency and fluid distribution. After a 1-week washout period, monkeys received radiolabeled siRNA targeting huntingtin. After 1 or 3 days of siRNA delivery, monkeys were either terminated, or their pumps were shut off and they were terminated 10 or 24 days later. Results indicate that the onset of huntingtin mRNA suppression in the rhesus putamen occurs rapidly, achieving a plateau throughout the putamen within 4 days. Conversely, loss of huntingtin suppression progresses slowly, persisting an estimated 27-39 days in the putamen and surrounding white matter. These findings indicate the rapid onset and durability of siRNA-mediated target gene suppression observed in other organs also occurs in the brain, and support the use of episodic delivery of siRNA into the brain for treatment of Huntington's disease and possibly other neurodegenerative diseases.

  8. The devitrification of artificial fibers: a multimethodic approach to quantify the temperature-time onset of cancerogenic crystalline phases.

    Science.gov (United States)

    Comodi, Paola; Cera, Fabio; Gatta, Giacomo Diego; Rotiroti, Nicola; Garofani, Patrizia

    2010-11-01

    A variety of artificial fibers extensively employed as lining in high-temperature apparatus may undergo a devitrification process that leads to significant changes in the chemical-physical properties of the materials. Among them, the crystallization of carcinogenic minerals, such as cristobalite, has already been documented for alumino-silicate ceramic fibers. Five fibrous samples with different compositions were treated over a wide range of temperatures (20-1500°C) and times (24-336 h) to investigate the rate and the crystalline phases that are formed as well their onset temperatures. The new phases were characterized by using a multimethodic approach: phase transformations were monitored together with thermal analysis and the new phases were investigated by using X-ray powder diffraction analysis. The crystalline:amorphous ratio was monitored by Rietveld refinement of X-ray diffraction data. Scanning electron microscopy was used to study the effect of heat treatments on the morphology of fibers, and the nanostructures were investigated by transmission electron microscopy (TEM). The results show that the main crystalline phases are cristobalite, diopside, mullite, and zirconia. The onset of cristobalite was observed at temperature lower than that thermodynamically expected. The TEM analysis showed that protostructures were present in the material vitrified from sol-gel-derived products, which can act as crystallization nuclei. The study shows that the devitrification leads to health hazard due to the formation of inhalable powder of cancerogenic crystalline phases.

  9. Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA

    Directory of Open Access Journals (Sweden)

    Richard Grondin

    2015-01-01

    Full Text Available One possible treatment for Huntington's disease involves direct infusion of a small, interfering RNA (siRNA designed to reduce huntingtin expression into brain tissue from a chronically implanted programmable pump. Here, we studied the suppression of huntingtin mRNA achievable with short infusion times, and investigated how long suppression may persist after infusion ceases. Rhesus monkeys received 3 days of infusion of Magnevist into the putamen to confirm catheter patency and fluid distribution. After a 1-week washout period, monkeys received radiolabeled siRNA targeting huntingtin. After 1 or 3 days of siRNA delivery, monkeys were either terminated, or their pumps were shut off and they were terminated 10 or 24 days later. Results indicate that the onset of huntingtin mRNA suppression in the rhesus putamen occurs rapidly, achieving a plateau throughout the putamen within 4 days. Conversely, loss of huntingtin suppression progresses slowly, persisting an estimated 27–39 days in the putamen and surrounding white matter. These findings indicate the rapid onset and durability of siRNA-mediated target gene suppression observed in other organs also occurs in the brain, and support the use of episodic delivery of siRNA into the brain for treatment of Huntington's disease and possibly other neurodegenerative diseases.

  10. Effect of switching time on timer-based burst assembly and its effect on voice-over-Internet protocol quality of service over optical burst switching networks

    Science.gov (United States)

    Tachibana, Takuji; Kurita, Kaori; Kasahara, Shoji

    2006-07-01

    It is well known that performance, such as burst loss probability and transmission delay, for optical burst switching (OBS) networks greatly depends on the switching time of the OBS switch. We analyze the switching-time effect on the burst loss probability using a continuous-time Markov chain. In our analysis, the transmission time of a burst is characterized with both the burst size and the switching time, and the burst loss probability, burst throughput, and data throughput are explicitly derived using the Geo,M/M/c/c queueing model. Numerical examples show that our analysis is quite useful for investigating the effect of the switching time on the timer-based burst assembly. We also consider voice-over-Internet Protocol (VoIP) service as a delay-sensitive application, and we investigate the switching time on the VoIP service. From our performance analysis, we derive an appropriate switching time and a burst processing time of the VoIP service in terms of the transmission distance.

  11. TET1 contributes to neurogenesis onset time during fetal brain development in mice.

    Science.gov (United States)

    Kim, Hyerim; Jang, Woo Young; Kang, Min-Cheol; Jeong, Jain; Choi, Minjee; Sung, Yonghun; Park, Song; Kwon, Wookbong; Jang, Soyoung; Kim, Myoung Ok; Kim, Sung Hyun; Ryoo, Zae Young

    2016-03-18

    Epigenetic mechanisms are relevant to development and contribute to fetal neurogenesis. DNA methylation and demethylation contribute to neural gene expression during mouse brain development. Ten-eleven translocation 1 (TET1) regulates DNA demethylation by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). TET1 specifically regulates 5hmC in the central nervous system (CNS), including during neurogenesis in the adult brain. However little is known about its function in fetal neurogenesis. In order to evaluate the role of TET1 in fetal brain development, we generated TET1-overexpressing transgenic (TG) mice. TET1 overexpression was confirmed in the brains of fetal mice, and we detected 5hmC overexpression in the TG brains compared to that in the wild type (WT) brains, using a dot-blot assay. In order to observe the role of TET1 in fetal brain development, we examined fetal brain samples at varied time points by using real-time PCR, Western blotting, and Immunofluorescence (IF). We confirmed that TET1 contributes to neurogenesis by upregulating the protein expressions of neuronal markers in the TG mouse brains, as determined by Western blotting. However the cortex structure or brain mass between WT and TG mice showed no significant difference by IF. In conclusion, TET1 makes the start time of neurogenesis earlier in the TG brains compared to that in the WT brains during fetal brain development.

  12. Space time development of the onset of a shallow-water vortex

    Science.gov (United States)

    Lin, J.-C.; Ozgoren, M.; Rockwell, D.

    2003-06-01

    An impulsively started jet in shallow water gives rise to vortices having a characteristic diameter larger than the water depth. A technique of high-image-density particle image velocimetry allows characterization of the space time development of the instantaneous flow patterns along planes representing the quasi-two-dimensional and three-dimensional vortex structure. The quasi-two-dimensional patterns exhibit different categories of vortex development and interaction, depending upon the depth of the shallow water layer. Despite these distinctions, the variations of normalized vortex position, diameter, and circulation, as well as peak vorticity within the vortex, are very similar for sufficiently small water depth.

  13. Work activities and the onset of first-time low back pain among New York City fire fighters.

    Science.gov (United States)

    Nuwayhid, I A; Stewart, W; Johnson, J V

    1993-03-01

    In a prospective study of first-time low back pain among New York City fire fighters, a total of 115 cases and 109 randomly selected controls were interviewed by telephone between December 1988 and July 1989 to examine the role of recent work activities in the onset of first-time low back pain. After adjusting for known risk factors and off-duty activities, statistically significant high-risk work activities included operating a charged hose inside a building (odds ratio (OR) = 3.26), climbing ladders (OR = 3.18), breaking windows (OR = 4.45), cutting structures (OR = 6.47), looking for hidden fires (OR = 4.32), and lifting objects > or = 18 kg (OR = 3.07). Low-risk activities included connecting hydrants to pumpers (OR = 0.36), pulling booster hose (OR = 0.19), and participating in drills (OR = 0.09) or physical training (OR = 0.16). When further adjusted for exposure to smoke (OR = 13.59), a surrogate for severity of alarms, the ORs associated with high-risk activities were no longer significant. This, however, does not diminish the role of activities in the onset of low back pain. Instead, it suggests an inseparable role for activities and environmental hazards. To examine this, the risk of low back pain was measured within five work zones sequential in time relative to location and distance from a structural fire. The risk gradually increased as the fire fighter moved away from the firehouse (OR = 0.10) and closer to the site of fire (OR = 3.91).

  14. Onset of effects of testosterone treatment and time span until maximum effects are achieved

    Science.gov (United States)

    Saad, Farid; Aversa, Antonio; Isidori, Andrea M; Zafalon, Livia; Zitzmann, Michael; Gooren, Louis

    2011-01-01

    Objective Testosterone has a spectrum of effects on the male organism. This review attempts to determine, from published studies, the time-course of the effects induced by testosterone replacement therapy from their first manifestation until maximum effects are attained. Design Literature data on testosterone replacement. Results Effects on sexual interest appear after 3 weeks plateauing at 6 weeks, with no further increments expected beyond. Changes in erections/ejaculations may require up to 6 months. Effects on quality of life manifest within 3–4 weeks, but maximum benefits take longer. Effects on depressive mood become detectable after 3–6 weeks with a maximum after 18–30 weeks. Effects on erythropoiesis are evident at 3 months, peaking at 9–12 months. Prostate-specific antigen and volume rise, marginally, plateauing at 12 months; further increase should be related to aging rather than therapy. Effects on lipids appear after 4 weeks, maximal after 6–12 months. Insulin sensitivity may improve within few days, but effects on glycemic control become evident only after 3–12 months. Changes in fat mass, lean body mass, and muscle strength occur within 12–16 weeks, stabilize at 6–12 months, but can marginally continue over years. Effects on inflammation occur within 3–12 weeks. Effects on bone are detectable already after 6 months while continuing at least for 3 years. Conclusion The time-course of the spectrum of effects of testosterone shows considerable variation, probably related to pharmacodynamics of the testosterone preparation. Genomic and non-genomic effects, androgen receptor polymorphism and intracellular steroid metabolism further contribute to such diversity. PMID:21753068

  15. The effect of heat shrink treatment and storage temperature on the time of onset of "blown pack" spoilage.

    Science.gov (United States)

    Moschonas, Galatios; Bolton, Declan J; Sheridan, James J; McDowell, David A

    2011-02-01

    This study determined the effects of (a) the short "heat shrink" treatment frequently applied to vacuum packed meats within normal commercial production, and (b) chill holding storage temperature, on the subsequent time to onset (TTO) of "blown pack" spoilage (BPS). Beef or lamb steaks were inoculated with 10³ CFU/cm² of spore suspensions of five gas producing clostridia, vacuum packed (VP) and treated as follows: no heat, 50°C/15 s, 70°C/10 s or 90°C/3 s. Samples were stored at -1.5, 1 or 4°C and examined daily to determine TTO of BPS. For each strain, pack treatment and storage temperature had significant (Pshrinking, and by storing VP meats at lower temperatures (e.g. -1.5°C).

  16. Advances on the automatic estimation of the P-wave onset time

    Directory of Open Access Journals (Sweden)

    Luz García

    2016-09-01

    Full Text Available This work describes the automatic picking of the P-phase arrivals of the 3*106 seismic registers originated during the TOMO-ETNA experiment. Air-gun shots produced by the vessel “Sarmiento de Gamboa” and contemporary passive seismicity occurring in the island are recorded by a dense network of stations deployed for the experiment. In such scenario, automatic processing is needed given: (i the enormous amount of data, (ii the low Signal-to-Noise ratio of many of the available registers and, (iii the accuracy needed for the velocity tomography resulting from the experiment. A preliminary processing is performed with the records obtained from all stations. Raw data formats from the different types of stations are unified, eliminating defective records and reducing noise through filtering in the band of interest for the phase picking. The Advanced Multiband Picking Algorithm (AMPA is then used to process the big database obtained and determine the travel times of the seismic phases. The approach of AMPA, based on frequency multiband denoising and enhancement of expected arrivals through optimum detectors, is detailed together with its calibration and quality assessment procedure. Examples of its usage for active and passive seismic events are presented.

  17. Dimensionality in voice quality.

    Science.gov (United States)

    Bele, Irene Velsvik

    2007-05-01

    This study concerns speaking voice quality in a group of male teachers (n = 35) and male actors (n = 36), as the purpose was to investigate normal and supranormal voices. The goal was the development of a method of valid perceptual evaluation for normal to supranormal and resonant voices. The voices (text reading at two loudness levels) had been evaluated by 10 listeners, for 15 vocal characteristics using VA scales. In this investigation, the results of an exploratory factor analysis of the vocal characteristics used in this method are presented, reflecting four dimensions of major importance for normal and supranormal voices. Special emphasis is placed on the effects on voice quality of a change in the loudness variable, as two loudness levels are studied. Furthermore, the vocal characteristics Sonority and Ringing voice quality are paid special attention, as the essence of the term "resonant voice" was a basic issue throughout a doctoral dissertation where this study was included.

  18. Voice box (image)

    Science.gov (United States)

    The larynx, or voice box, is located in the neck and performs several important functions in the body. The larynx is involved in swallowing, breathing, and voice production. Sound is produced when the air which ...

  19. Voice and Aging

    Science.gov (United States)

    ... dramatic voice changes are those during childhood and adolescence. The larynx (or voice box) and vocal cord tissues do not fully mature until late teenage years. Hormone-related changes during adolescence are ...

  20. Voice parameters and videonasolaryngoscopy in children with vocal nodules: a longitudinal study, before and after voice therapy.

    Science.gov (United States)

    Valadez, Victor; Ysunza, Antonio; Ocharan-Hernandez, Esther; Garrido-Bustamante, Norma; Sanchez-Valerio, Araceli; Pamplona, Ma C

    2012-09-01

    Vocal Nodules (VN) are a functional voice disorder associated with voice misuse and abuse in children. There are few reports addressing vocal parameters in children with VN, especially after a period of vocal rehabilitation. The purpose of this study is to describe measurements of vocal parameters including Fundamental Frequency (FF), Shimmer (S), and Jitter (J), videonasolaryngoscopy examination and clinical perceptual assessment, before and after voice therapy in children with VN. Voice therapy was provided using visual support through Speech-Viewer software. Twenty patients with VN were studied. An acoustical analysis of voice was performed and compared with data from subjects from a control group matched by age and gender. Also, clinical perceptual assessment of voice and videonasolaryngoscopy were performed to all patients with VN. After a period of voice therapy, provided with visual support using Speech Viewer-III (SV-III-IBM) software, new acoustical analyses, perceptual assessments and videonasolaryngoscopies were performed. Before the onset of voice therapy, there was a significant difference (ptherapy period, a significant improvement (pvocal nodules were no longer discernible on the vocal folds in any of the cases. SV-III software seems to be a safe and reliable method for providing voice therapy in children with VN. Acoustic voice parameters, perceptual data and videonasolaryngoscopy were significantly improved after the speech therapy period was completed. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  1. Voice and endocrinology

    OpenAIRE

    KVS Hari Kumar; Anurag Garg; Ajai Chandra, N. S.; Singh, S. P.; Rakesh Datta

    2016-01-01

    Voice is one of the advanced features of natural evolution that differentiates human beings from other primates. The human voice is capable of conveying the thoughts into spoken words along with a subtle emotion to the tone. This extraordinary character of the voice in expressing multiple emotions is the gift of God to the human beings and helps in effective interpersonal communication. Voice generation involves close interaction between cerebral signals and the peripheral apparatus consistin...

  2. DLMS Voice Data Entry.

    Science.gov (United States)

    1980-06-01

    between operator and computer displayed on ADM-3A 20c A-I Possible Hardware Configuration for a Multistation Cartographic VDES ...this program a Voice Recognition System (VRS) which can be used to explore the use of voice data entry ( VDE ) in the DIMS or other cartographic data...Multi-Station Cartographic Voice Data Entry System An engineering development model voice data entry system ( VDES ) could be most efficiently

  3. Is postpartum depression a homogenous disorder: time of onset, severity, symptoms and hopelessness in relation to the course of depression.

    Science.gov (United States)

    Kettunen, Pirjo; Koistinen, Eeva; Hintikka, Jukka

    2014-12-10

    Postpartum depression (PPD) is a common illness, but due to the underlying processes and the diversity of symptoms, some variability is exhibited. The risk of postpartum depression is great if the mother has previously suffered from depression, but there is some evidence that a certain subgroup of women only experience depression during the postpartum period. The study group consisted of 104 mothers with postpartum major depression and a control group of 104 postpartum mothers without depression. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) was used for data collection. The severity of depression and other mental symptoms were assessed using several validated rating scales. A history of past depression (82%), including depression during pregnancy (42%) and during the postpartum period (53%), was very common in those with current PPD. Eighteen per cent of mothers with current PPD had previously not had any depressive episodes and four per cent had experienced depression only during the postpartum period. Therefore, pure PPD was rare. The onset of PPD was usually (84%) within six weeks of childbirth. Obsessive-compulsive symptoms, phobic anxiety, paranoid ideation, depressed mood, diminished pleasure/interest, decreased energy, and psychomotor agitation/retardation were common with all kinds of depression histories. Pure PPD was the most similar to the first depressive episode. Nevertheless, the severity of depression, the level of hopelessness, somatisation, interpersonal sensitivity, anxiety, hostility, psychoticism, sleep disturbance, and suicidal ideation were lower, appetite changed less, and concentration was better than in other recurrent depressions. According to this study, PPD is not a homogenous disorder. The time of onset, severity, symptoms, level of hopelessness, and the course of depression vary. Recurrent depression is common. All mothers must be screened during the sixth week postpartum at the latest. Screening alone is not

  4. Development of a multiplex real-time PCR assay for the rapid diagnosis of neonatal late onset sepsis.

    Science.gov (United States)

    van den Brand, Marre; Peters, Remco P H; Catsburg, Arnold; Rubenjan, Anna; Broeke, Ferdi J; van den Dungen, Frank A M; van Weissenbruch, Mirjam M; van Furth, A Marceline; Kõressaar, Triinu; Remm, Maido; Savelkoul, Paul H M; Bos, Martine P

    2014-11-01

    The diagnosis of late onset sepsis (LOS), a severe condition with high prevalence in preterm infants, is hampered by the suboptimal sensitivity and long turnaround time of blood culture. Detection of the infecting pathogen directly in blood by PCR would provide a much more timely result. Unfortunately, PCR-based assays reported so far are labor intensive and often lack direct species identification. Therefore we developed a real-time multiplex PCR assay tailored to LOS diagnosis which is easy-to-use, is applicable on small blood volumes and provides species-specific results within 4h. Species-specific PCR assays were selected from literature or developed using bioinformatic tools for the detection of the most prevalent etiologic pathogens: Enterococcus faecalis, Staphylococcus aureus, Staphylococcus spp., Streptococcus agalactiae, Escherichia coli, Pseudomonas aeruginosa, Klebsiella spp. and Serratia marcescens. The PCR assays showed 100% specificity, full coverage of the target pathogens and a limit of detection (LOD) of ≤10CFUeq./reaction. These LOD values were maintained in the multiplex format or when bacterial DNA was isolated from blood. Clinical evaluation showed high concordance between the multiplex PCR and blood culture. In conclusion, we developed a multiplex PCR that allows the direct detection of the most important bacterial pathogens causing LOS in preterm infants.

  5. The journey of rheumatoid arthritis patients: a review of reported lag times from the onset of symptoms

    Directory of Open Access Journals (Sweden)

    Barhamain AS

    2017-07-01

    Full Text Available Alaa S Barhamain,1 Rami F Magliah,1 Mohammad H Shaheen,1 Shurooq F Munassar,1 Ayman M Falemban,1 Mohammed M Alshareef,1 Hani M Almoallim1–3 1Department of Medicine, Faculty of Medicine, 2Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, 3Department of Medicine, Dr Soleiman Fakeeh Hospital, Jeddah, Saudi Arabia Background: Even after achieving tremendous advances in diagnosis and treatment of rheumatoid arthritis (RA, many of the patients undergo delays in diagnosis and initiation of treatment, which leads to worsening of the condition and poor prognosis. Objective: The objective of this study was to perform a literature review to quantify the lag times in diagnosis and treatment of RA and study the reported factors associated with it.Methods: The authors searched literature published until September 2016 in electronic full-text and abstract databases and hand-searched the suitable articles. Results: The weighted average of median lag time from symptom onset to therapy was 11.79 months (12 studies, 5,512 patients, range 3.6–24.0 months. Lag1 was 3.14 months (onset of symptoms to first physician consultant; 12 studies, 6,055 patients, range 0–5.7 months; lag2 was 2.13 months (physician visit to RA specialist referral; 13 studies, 34,767 patients, range 0.5–6.6 months; lag3 was 2.91 months (consultation with rheumatologist to diagnosis; 3 studies, 563 patients, range 0–5 months, lag4 was 2.14 months (diagnosis to initiation of disease-modifying antirheumatic drug therapy; 5 studies, 30,685 patients, range 0–2.2 months. Numerous patient- and physician-related factors like gender, ethnicity, primary care physician knowledge of the condition, availability of diagnostics, and so on were responsible for the delays.Conclusion: This review estimated the delay times and identified the main factors for delay in RA patients in diagnosis and initiation of treatment. A most plausible solution to this is coordinated

  6. Writing with Voice

    Science.gov (United States)

    Kesler, Ted

    2012-01-01

    In this Teaching Tips article, the author argues for a dialogic conception of voice, based in the work of Mikhail Bakhtin. He demonstrates a dialogic view of voice in action, using two writing examples about the same topic from his daughter, a fifth-grade student. He then provides five practical tips for teaching a dialogic conception of voice in…

  7. Tips for Healthy Voices

    Science.gov (United States)

    ... social interaction as well as for most people’s occupation. Proper care and use of your voice will give you the best chance for having a healthy voice for your entire lifetime. Hoarseness or roughness in your voice is often ...

  8. Timing of Tissue-specific Cell Division Requires a Differential Onset of Zygotic Transcription during Metazoan Embryogenesis.

    Science.gov (United States)

    Wong, Ming-Kin; Guan, Daogang; Ng, Kaoru Hon Chun; Ho, Vincy Wing Sze; An, Xiaomeng; Li, Runsheng; Ren, Xiaoliang; Zhao, Zhongying

    2016-06-10

    Metazoan development demands not only precise cell fate differentiation but also accurate timing of cell division to ensure proper development. How cell divisions are temporally coordinated during development is poorly understood. Caenorhabditis elegans embryogenesis provides an excellent opportunity to study this coordination due to its invariant development and widespread division asynchronies. One of the most pronounced asynchronies is a significant delay of cell division in two endoderm progenitor cells, Ea and Ep, hereafter referred to as E2, relative to its cousins that mainly develop into mesoderm organs and tissues. To unravel the genetic control over the endoderm-specific E2 division timing, a total of 822 essential and conserved genes were knocked down using RNAi followed by quantification of cell cycle lengths using in toto imaging of C. elegans embryogenesis and automated lineage. Intriguingly, knockdown of numerous genes encoding the components of general transcription pathway or its regulatory factors leads to a significant reduction in the E2 cell cycle length but an increase in cell cycle length of the remaining cells, indicating a differential requirement of transcription for division timing between the two. Analysis of lineage-specific RNA-seq data demonstrates an earlier onset of transcription in endoderm than in other germ layers, the timing of which coincides with the birth of E2, supporting the notion that the endoderm-specific delay in E2 division timing demands robust zygotic transcription. The reduction in E2 cell cycle length is frequently associated with cell migration defect and gastrulation failure. The results suggest that a tissue-specific transcriptional activation is required to coordinate fate differentiation, division timing, and cell migration to ensure proper development.

  9. Parâmetros acústicos do contraste de sonoridade das plosivas no desenvolvimento fonológico típico e no desviante Acoustic parameters of the voicing contrast of plosives in typical phonological development and phonological disorder

    Directory of Open Access Journals (Sweden)

    Roberta Michelon Melo

    2012-01-01

    Full Text Available OBJETIVO: Investigar se as crianças com desvio fonológico apresentam características acústicas distintas de sons plosivos surdos e sonoros das crianças com desenvolvimento fonológico típico. MÉTODOS:Participaram do estudo 11 crianças com desenvolvimento fonológico típico e cinco com desvio fonológico e dificuldade na aquisição do traço [+voz] das consoantes plosivas. Por meio de palavras (['papa], ['baba], ['tata], ['dada], ['kaka] e ['gaga] inseridas em frases-veículo, mediu-se o voice onset time, a duração da vogal, a amplitude do burst e a duração da oclusão de cada plosivo. Foram comparados todos os registros acústicos de plosivos surdos e sonoros intra e intergrupo, por meio de testes estatísticos. RESULTADOS: As crianças com desenvolvimento fonológico típico apresentaram resultados significativos, principalmente, na diferenciação dos parâmetros de voice onset time, duração da vogal e oclusão de plosivos surdos e sonoros, diferentemente do observado para as crianças com desvio fonológico. A comparação entre os dois grupos mostrou diferenças quanto à produção de voice onset time e duração da oclusão dos plosivos sonoros. Com relação aos demais parâmetros analisados, os valores foram aproximados entre os grupos, sem diferença estatística. CONCLUSÃO: A marcação do contraste de sonoridade do grupo desviante mostra-se distinta em relação ao grupo de crianças com desenvolvimento fonológico típico, principalmente no que se refere ao voice onset time e à duração da oclusão dos segmentos sonoros.PURPOSE: To investigate if children with phonological disorder present different acoustic characteristics of voiceless and voiced plosives from children with typical phonological development. METHODS: Participants were 11 children with typical phonological development and five children with phonological disorder and difficulty to establish the distinctive feature [+voice] of plosives. Through words

  10. The clinical utility of vocal dosimetry for assessing voice rest.

    Science.gov (United States)

    Misono, Stephanie; Banks, Kathryn; Gaillard, Philippe; Goding, George S; Yueh, Bevan

    2015-01-01

    Voice rest is frequently recommended following surgical disruption of vocal fold epithelium, but patients report variable adherence to voice rest recommendations. The objective of this study was to assess the clinical utility of an ambulatory vocal dosimeter for measuring adherence to voice rest recommendations. Outcomes research. Part 1: To determine the utility of the dosimeter in nonclinical use, the relationship between self-reported voice use and dosimeter measurements was examined in normal subjects (n = 11) who prospectively logged voice use while wearing the dosimeter. Part 2: To determine clinical utility of the dosimeter, patients undergoing vocal fold surgery for which postoperative voice rest was recommended (n = 11) wore a dosimeter for 2 days prior to and 2 days after surgery. Phonation percent and sound level were compared at baseline and during voice rest. The dosimeter performed as hypothesized with both normal subjects and patients. A moderate correlation (r = 0.62) was noted between self-reported voice use and dosimeter measurements in normal subjects. In patients on voice rest, a statistically and clinically significant decrease was observed in measured voice use, both in phonation time (P = .002) and intensity of phonation (P = .004). Ambulatory vocal dosimetry may have clinical utility for assessing adherence to voice rest recommendations. This information will be useful for the design of future studies on voice rest. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

  11. Voice handicap in singers.

    Science.gov (United States)

    Murry, Thomas; Zschommler, Anne; Prokop, Jan

    2009-05-01

    The study aimed to determine the differences in responses to the Voice Handicap Index (VHI-10) between singers and nonsingers and to evaluate the ranked order differences of the VHI-10 statements for both groups. The VHI-10 was modified to include statements related to the singing voice for comparison to the original VHI-10. Thirty-five nonsingers with documented voice disorders responded to the VHI-10. A second group, consisting of 35 singers with voice complaints, responded to the VHI-10 with three statements added specifically addressing the singing voice. Data from both groups were analyzed in terms of overall subject self-rating of voice handicap and the rank order of statements from least to most important. The difference between the mean VHI-10 for the singers and nonsingers was not statistically significant, thus, supporting the validity of the VHI-10. However, the 10 statements were ranked differently in terms of their importance by both groups. In addition, when three statements related specifically to the singing voice were substituted in the original VHI-10, the singers judged their voice problem to be more severe than when using the original VHI-10. The type of statements used to assess self-perception of voice handicap may be related to the subject population. Singers with voice problems do not rate their voices to be more handicapped than nonsingers unless statements related specifically to singing are included.

  12. Voices in History

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    Ivan Leudar

    2001-06-01

    Full Text Available Experiences of “hearing voices” nowadays usually count as verbal hallucinations and they indicate serious mental illness. Some are first rank symptoms of schizophrenia, and the mass media, at least in Britain, tend to present them as antecedents of impulsive violence. They are, however, also found in other psychiatric conditions and epidemiological surveys reveal that even individuals with no need of psychiatric help can hear voices, sometimes following bereavement or abuse, but sometimes for no discernible reason. So do these experiences necessarily mean insanity and violence, and must they be thought of as pathogenic hallucinations; or are there other ways to understand them and live with them, and with what consequences?One way to make our thinking more flexible is to turn to history. We find that hearing voices was always an enigmatic experience, and the people who had it were rare. The gallery of voice hearers is, though, distinguished and it includes Galilei, Bunyan and St Teresa. Socrates heard a daemon who guided his actions, but in his time this did not signify madness, nor was it described as a hallucination. Yet in 19th century French psychological medicine the daemon became a hallucination and Socrates was retrospectively diagnosed as mentally ill. This paper examines the controversies which surrounded the experience at different points in history as well as the practice of retrospective psychiatry. The conclusion reached on the basis of the historical materials is that the experience and the ontological status it is ascribed are not trans-cultural or trans-historic but situated both in history and in the contemporary conflicts.

  13. Impact of time from symptom onset to drug administration on outcome in patients undergoing glycoprotein IIb-IIIa facilitated primary angioplasty (from the EGYPT cooperation).

    Science.gov (United States)

    De Luca, Giuseppe; Van't Hof, Arnoud W J; Gibson, C Michael; Cutlip, Donald; Zeymer, Uwe; Noc, Marko; Maioli, Mauro; Zorman, Simona; Gabriel, H Mesquita; Emre, Ayse; Rakowski, Tomasz; Gyongyosi, Maryann; Huber, Kurt; Bellandi, Francesco; Dudek, Dariusz

    2015-03-15

    Contrasting data have been so far reported on facilitation with glycoprotein IIb-IIIa inhibitors (GpIIbIIIa) in patients who underwent primary percutaneous coronary intervention. However, it has been demonstrated a time-dependent composition of coronary thrombus in ST-segment elevation myocardial infarction, with more platelets in the first hours. Subsequently, the benefits of early administration of GpIIbIIIa may be affected by the time from symptoms onset to GpIIbIIIa, that therefore is the aim of this study. Our population is represented by 814 patients who underwent GpIIbIIIa facilitated primary angioplasty included in the Early glycoprotein IIb-IIIa inhibitors in primary angioplasty database. Patients were divided according to quartiles of time from symptom onset to GpIIbIIIa administration (≤65 minutes; 65 to 100 minutes; 101 to 178 minutes; and >178 minutes). Myocardial perfusion was evaluated by myocardial blush grade and ST-segment resolution. Time from symptoms onset to GpIIbIIIa was linearly associated with hypertension, diabetes, hypercholesterolemia, and previous myocardial infarction but inversely associated with smoking. Abciximab was more often administrated later from symptoms onset. Time from symptoms onset to GpIIbIIIa was significantly associated with the rate of preprocedural recanalization (thrombolysis in myocardial infarction [TIMI] 2 to 3; p Time to GpIIbIIIa had a significant impact on mortality (hazard ratio [95% confidence interval] 1.46 [1.11 to 1.92], p = 0.007) that was confirmed after correction for baseline confounding factors (adjusted hazard ratio [95% confidence interval] 1.41 [1.02 to 2.21], p = 0.042). In conclusion, this study showed that in patients who underwent primary angioplasty with upstream GpIIbIIIa, time from symptoms onset to GpIIbIIIa strongly impacts on preprocedural recanalization, distal embolization, myocardial perfusion, and long-term survival.

  14. Objective Voice Parameters in Colombian School Workers with Healthy Voices

    Directory of Open Access Journals (Sweden)

    Lady Catherine Cantor Cutiva

    2015-09-01

    Full Text Available Objectives: To characterize the objective voice parameters among school workers, and to identi­fy associated factors of three objective voice parameters, namely fundamental frequency, sound pressure level and maximum phonation time. Materials and methods: We conducted a cross-sectional study among 116 Colombian teachers and 20 Colombian non-teachers. After signing the informed consent form, participants filled out a questionnaire. Then, a voice sample was recorded and evaluated perceptually by a speech therapist and by objective voice analysis with praat software. Short-term environmental measurements of sound level, temperature, humi­dity, and reverberation time were conducted during visits at the workplaces, such as classrooms and offices. Linear regression analysis was used to determine associations between individual and work-related factors and objective voice parameters. Results: Compared with men, women had higher fundamental frequency (201 Hz for teachers and 209 for non-teachers vs. 120 Hz for teachers and 127 for non-teachers and sound pressure level (82 dB vs. 80 dB, and shorter maximum phonation time (around 14 seconds vs. around 16 seconds. Female teachers younger than 50 years of age evidenced a significant tendency to speak with lower fundamental frequen­cy and shorter mpt compared with female teachers older than 50 years of age. Female teachers had significantly higher fundamental frequency (66 Hz, higher sound pressure level (2 dB and short phonation time (2 seconds than male teachers. Conclusion: Female teachers younger than 50 years of age had significantly lower F0 and shorter mpt compared with those older than 50 years of age. The multivariate analysis showed that gender was a much more important determinant of variations in F0, spl and mpt than age and teaching occupation. Objectively measured temperature also contributed to the changes on spl among school workers.

  15. Etude du Voice Onset Time (V.O.T dans des séquences VCV produites par des patients francophones souffrants de paralysies récurrentielles

    Directory of Open Access Journals (Sweden)

    Fauth Camille

    2014-07-01

    Notre étude se veut longitudinale puisque la voix des patients est enregistrée lors de différentes phases post-opératoires (post-opératoire 2, 3 et 4, ce qui devrait nous permettre de mettre au jour, non seulement les perturbations provoquées par l’immobilité laryngée, mais également les réajustements que les patients pourraient mettre en place au cours du temps et de leur rééducation orthophonique. Seul l’intervalle du VOT pour les occlusives sonores a été modifié. Pour les occlusives voisées, la transition CV implique uniquement un changement d’un état obstrué de conduit vocal à un état suffisamment dégagé de celui-ci pour permettre l’apparition d’une structure formantique claire et stable. En revanche, pour les occlusives non voisées, cette transition CV exige, outre le changement d’état du conduit vocal, une modification de la configuration de la glotte d’une position ouverte pour la consonne non voisée à une position fermée pour la voyelle subséquente. En conséquence, en raison de difficultés de maintien de vibrations laryngées, le VOT, qui est un indice de voisement, est alors généralement plus long pour les occlusives voisées que celles produites par les locuteurs contrôles. La durée du VOT de Klatt (1975 des occlusives voisées des patients reste toutefois quantitativement distincte des occlusives non voisées. En conséquence, la durée de la tenue consonantique des patients se voit également allongée dans les phases d’enregistrement précoces.

  16. On the Interpretation of Response Time vs Onset Asynchrony Functions: Application to Dual-Task and Precue-Utilization Paradigms.

    Science.gov (United States)

    Schwarz, Wolfgang; Ischebeck, Anja

    2001-06-01

    The central bottleneck model of dual-task performance (H. Pashler and J. C. Johnston, 1998, Quarterly Journal of Experimental Psychology, 46A, 51-82) and the serial processing model of precue utilization (R. Gottsdanker, 1992, Acta Psychologica, 79, 21-43) are based on a common formal structure: They both represent response time as RT(tau)=max(X-tau, Y)+Z, where X, Y, Z denote the duration of certain processing stages specified by the models and tau denotes the onset asynchrony (SOA) between two stimuli. We consider this model within a stochastic framework in which the stage durations are random variables following an arbitrary joint distribution and derive properties of the function relating E[RT(tau)] to SOA. We present a distribution-free result which relates the slope of this function to the distribution of the random durations of the assumed processing stages. Our results allow for a direct, model-based interpretation of data from related experiments; specifically, they show how the slope of the SOA-function depends on experimental factors which selectively influence individual processing stages. We explain the implications of our results for models of dual-task performance and precue utilization and illustrate their application to data obtained by M. C. Smith (1969, Acta Psychologica, 30, 220-231) and R. Gottsdanker (1992, loc. cit.) Copyright 2001 Academic Press.

  17. Slow-Onset Inhibition of the FabI Enoyl Reductase from Francisella tularensis: Residence Time and in Vivo Activity

    Energy Technology Data Exchange (ETDEWEB)

    Lu, H.; England, K; Ende, C; Truglio, J; Luckner, S; Reddy, B; Marlenee, N; Knudson, S; Knudson, D; et. al.

    2009-01-01

    Francisella tularensis is a highly virulent and contagious Gram-negative intracellular bacterium that causes the disease tularemia in mammals. The high infectivity and the ability of the bacterium to survive for weeks in a cool, moist environment have raised the possibility that this organism could be exploited deliberately as a potential biological weapon. Fatty acid biosynthesis (FAS-II) is essential for bacterial viability and has been validated as a target for the discovery of novel antibacterials. The FAS-II enoyl reductase ftuFabI has been cloned and expressed, and a series of diphenyl ethers have been identified that are subnanomolar inhibitors of the enzyme with MIC90 values as low as 0.00018 ?g mL-1. The existence of a linear correlation between the Ki and MIC values strongly suggests that the antibacterial activity of the diphenyl ethers results from direct inhibition of ftuFabI within the cell. The compounds are slow-onset inhibitors of ftuFabI, and the residence time of the inhibitors on the enzyme correlates with their in vivo activity in a mouse model of tularemia infection. Significantly, the rate of breakdown of the enzyme-inhibitor complex is a better predictor of in vivo activity than the overall thermodynamic stability of the complex, a concept that has important implications for the discovery of novel chemotherapeutics that normally rely on equilibrium measurements of potency.

  18. Voice Use Among Music Theory Teachers: A Voice Dosimetry and Self-Assessment Study.

    Science.gov (United States)

    Schiller, Isabel S; Morsomme, Dominique; Remacle, Angélique

    2017-07-25

    This study aimed (1) to investigate music theory teachers' professional and extra-professional vocal loading and background noise exposure, (2) to determine the correlation between vocal loading and background noise, and (3) to determine the correlation between vocal loading and self-evaluation data. Using voice dosimetry, 13 music theory teachers were monitored for one workweek. The parameters analyzed were voice sound pressure level (SPL), fundamental frequency (F0), phonation time, vocal loading index (VLI), and noise SPL. Spearman correlation was used to correlate vocal loading parameters (voice SPL, F0, and phonation time) and noise SPL. Each day, the subjects self-assessed their voice using visual analog scales. VLI and self-evaluation data were correlated using Spearman correlation. Vocal loading parameters and noise SPL were significantly higher in the professional than in the extra-professional environment. Voice SPL, phonation time, and female subjects' F0 correlated positively with noise SPL. VLI correlated with self-assessed voice quality, vocal fatigue, and amount of singing and speaking voice produced. Teaching music theory is a profession with high vocal demands. More background noise is associated with increased vocal loading and may indirectly increase the risk for voice disorders. Correlations between VLI and self-assessments suggest that these teachers are well aware of their vocal demands and feel their effect on voice quality and vocal fatigue. Visual analog scales seem to represent a useful tool for subjective vocal loading assessment and associated symptoms in these professional voice users. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  19. Stroke With Unknown Time of Symptom Onset: Baseline Clinical and Magnetic Resonance Imaging Data of the First Thousand Patients in WAKE-UP

    DEFF Research Database (Denmark)

    Thomalla, Götz; Boutitie, Florent; Fiebach, Jochen B

    2017-01-01

    BACKGROUND AND PURPOSE: We describe clinical and magnetic resonance imaging (MRI) characteristics of stroke patients with unknown time of symptom onset potentially eligible for thrombolysis from a large prospective cohort. METHODS: We analyzed baseline data from WAKE-UP (Efficacy and Safety of MR...... a time window for safe and effective thrombolysis. Patients with daytime onset unwitnessed stroke differ from wake-up stroke patients with regards to clinical characteristics but are comparable in terms of MRI characteristics of lesion age. CLINICAL TRIAL REGISTRATION: URL: http......://www.clinicaltrials.gov. Unique identifier: NCT01525290. URL: https://www.clinicaltrialsregister.eu. Unique identifier: 2011-005906-32....

  20. Stop consonant voicing in young children's speech: Evidence from a cross-sectional study

    Science.gov (United States)

    Ganser, Emily

    There are intuitive reasons to believe that speech-sound acquisition and language acquisition should be related in development. Surprisingly, only recently has research begun to parse just how the two might be related. This study investigated possible correlations between speech-sound acquisition and language acquisition, as part of a large-scale, longitudinal study of the relationship between different types of phonological development and vocabulary growth in the preschool years. Productions of voiced and voiceless stop-initial words were recorded from 96 children aged 28-39 months. Voice Onset Time (VOT, in ms) for each token context was calculated. A mixed-model logistic regression was calculated which predicted whether the sound was intended to be voiced or voiceless based on its VOT. This model estimated the slopes of the logistic function for each child. This slope was referred to as Robustness of Contrast (based on Holliday, Reidy, Beckman, and Edwards, 2015), defined as being the degree of categorical differentiation between the production of two speech sounds or classes of sounds, in this case, voiced and voiceless stops. Results showed a wide range of slopes for individual children, suggesting that slope-derived Robustness of Contrast could be a viable means of measuring a child's acquisition of the voicing contrast. Robustness of Contrast was then compared to traditional measures of speech and language skills to investigate whether there was any correlation between the production of stop voicing and broader measures of speech and language development. The Robustness of Contrast measure was found to correlate with all individual measures of speech and language, suggesting that it might indeed be predictive of later language skills.

  1. Unexpected spatial intensity distributions and onset timing of solar electron events observed by closely spaced STEREO spacecraft

    Science.gov (United States)

    Klassen, A.; Dresing, N.; Gómez-Herrero, R.; Heber, B.; Müller-Mellin, R.

    2016-09-01

    We present multi-spacecraft observations of four solar electron events using measurements from the Solar Electron Proton Telescope (SEPT) and the Electron Proton Helium INstrument (EPHIN) on board the STEREO and SOHO spacecraft, respectively, occurring between 11 October 2013 and 1 August 2014, during the approaching superior conjunction period of the two STEREO spacecraft. At this time the longitudinal separation angle between STEREO-A (STA) and STEREO-B (STB) was less than 72°. The parent particle sources (flares) of the four investigated events were situated close to, in between, or to the west of the STEREO's magnetic footpoints. The STEREO measurements revealed a strong difference in electron peak intensities (factor ≤12) showing unexpected intensity distributions at 1 AU, although the two spacecraft had nominally nearly the same angular magnetic footpoint separation from the flaring active region (AR) or their magnetic footpoints were both situated eastwards from the parent particle source. Furthermore, the events detected by the two STEREO imply a strongly unexpected onset timing with respect to each other: the spacecraft magnetically best connected to the flare detected a later arrival of electrons than the other one. This leads us to suggest the concept of a rippled peak intensity distribution at 1 AU formed by narrow peaks (fingers) superposed on a quasi-uniform Gaussian distribution. Additionally, two of the four investigated solar energetic particle (SEP) events show a so-called circumsolar distribution and their characteristics make it plausible to suggest a two-component particle injection scenario forming an unusual, non-uniform intensity distribution at 1 AU.

  2. A temporal predictive code for voice motor control: Evidence from ERP and behavioral responses to pitch-shifted auditory feedback.

    Science.gov (United States)

    Behroozmand, Roozbeh; Sangtian, Stacey; Korzyukov, Oleg; Larson, Charles R

    2016-04-01

    The predictive coding model suggests that voice motor control is regulated by a process in which the mismatch (error) between feedforward predictions and sensory feedback is detected and used to correct vocal motor behavior. In this study, we investigated how predictions about timing of pitch perturbations in voice auditory feedback would modulate ERP and behavioral responses during vocal production. We designed six counterbalanced blocks in which a +100 cents pitch-shift stimulus perturbed voice auditory feedback during vowel sound vocalizations. In three blocks, there was a fixed delay (500, 750 or 1000 ms) between voice and pitch-shift stimulus onset (predictable), whereas in the other three blocks, stimulus onset delay was randomized between 500, 750 and 1000 ms (unpredictable). We found that subjects produced compensatory (opposing) vocal responses that started at 80 ms after the onset of the unpredictable stimuli. However, for predictable stimuli, subjects initiated vocal responses at 20 ms before and followed the direction of pitch shifts in voice feedback. Analysis of ERPs showed that the amplitudes of the N1 and P2 components were significantly reduced in response to predictable compared with unpredictable stimuli. These findings indicate that predictions about temporal features of sensory feedback can modulate vocal motor behavior. In the context of the predictive coding model, temporally-predictable stimuli are learned and reinforced by the internal feedforward system, and as indexed by the ERP suppression, the sensory feedback contribution is reduced for their processing. These findings provide new insights into the neural mechanisms of vocal production and motor control.

  3. Silence and Voicing Accumulations in Italian Primary School Teachers With and Without Voice Disorders.

    Science.gov (United States)

    Bottalico, Pasquale; Graetzer, Simone; Astolfi, Arianna; Hunter, Eric J

    2017-03-01

    The relationship between the silence and voicing accumulations of primary school teachers and the teachers' clinical status was examined to determine whether more voicing accumulations and fewer silence accumulations were measured for the vocally unhealthy subjects than for the healthy subjects, which would imply more vocal loading and fewer short-term recovery moments. Twenty-six Italian primary school teachers were allocated by clinicians to three groups: (1) with organic voice disorders, (2) with subjectively mild organic alteration or functional voice symptoms, and (3) normal voice quality and physiology. Continuous silence and voicing periods were measured with the APM3200 during the teachers' 4-hour workdays. The accumulations were grouped into seven time intervals, ranging from 0.03-0.9 to 3.16-10 seconds, according to Italian prosody. The effects of group on silence and voicing accumulations were evaluated. Regarding silence accumulations, Group 1 accumulated higher values in intervals between 0.1 and 3.15 seconds than other groups, whereas Groups 2 and 3 did not differ from each other. Voicing accumulations between 0.17 and 3.15 seconds were higher for subjects with a structural disorder. A higher time dose was accumulated by these subjects (40.6%) than other subjects (Group 2, 31.9%; Group 3, 32.3%). Although previous research has suggested that a rest period of a few seconds may produce some vocal fatigue recovery, these results indicate that periods shorter than 3.16 seconds may not have an observable effect on recovery. The results provide insight into how vocal fatigue and vocal recovery may relate to voice disorders in occupational voice users. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  4. Singing voice outcomes following singing voice therapy.

    Science.gov (United States)

    Dastolfo-Hromack, Christina; Thomas, Tracey L; Rosen, Clark A; Gartner-Schmidt, Jackie

    2016-11-01

    The objectives of this study were to describe singing voice therapy (SVT), describe referred patient characteristics, and document the outcomes of SVT. Retrospective. Records of patients receiving SVT between June 2008 and June 2013 were reviewed (n = 51). All diagnoses were included. Demographic information, number of SVT sessions, and symptom severity were retrieved from the medical record. Symptom severity was measured via the 10-item Singing Voice Handicap Index (SVHI-10). Treatment outcome was analyzed by diagnosis, history of previous training, and SVHI-10. SVHI-10 scores decreased following SVT (mean change = 11, 40% decrease) (P singing lessons (n = 10) also completed an average of three SVT sessions. Primary muscle tension dysphonia (MTD1) and benign vocal fold lesion (lesion) were the most common diagnoses. Most patients (60%) had previous vocal training. SVHI-10 decrease was not significantly different between MTD and lesion. This is the first outcome-based study of SVT in a disordered population. Diagnosis of MTD or lesion did not influence treatment outcomes. Duration of SVT was short (approximately three sessions). Voice care providers are encouraged to partner with a singing voice therapist to provide optimal care for the singing voice. This study supports the use of SVT as a tool for the treatment of singing voice disorders. 4 Laryngoscope, 126:2546-2551, 2016. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

  5. Speaking modifies voice-evoked activity in the human auditory cortex.

    Science.gov (United States)

    Curio, G; Neuloh, G; Numminen, J; Jousmäki, V; Hari, R

    2000-04-01

    The voice we most often hear is our own, and proper interaction between speaking and hearing is essential for both acquisition and performance of spoken language. Disturbed audiovocal interactions have been implicated in aphasia, stuttering, and schizophrenic voice hallucinations, but paradigms for a noninvasive assessment of auditory self-monitoring of speaking and its possible dysfunctions are rare. Using magnetoencephalograpy we show here that self-uttered syllables transiently activate the speaker's auditory cortex around 100 ms after voice onset. These phasic responses were delayed by 11 ms in the speech-dominant left hemisphere relative to the right, whereas during listening to a replay of the same utterances the response latencies were symmetric. Moreover, the auditory cortices did not react to rare vowel changes interspersed randomly within a series of repetitively spoken vowels, in contrast to regular change-related responses evoked 100-200 ms after replayed rare vowels. Thus, speaking primes the human auditory cortex at a millisecond time scale, dampening and delaying reactions to self-produced "expected" sounds, more prominently in the speech-dominant hemisphere. Such motor-to-sensory priming of early auditory cortex responses during voicing constitutes one element of speech self-monitoring that could be compromised in central speech disorders.

  6. The chemical exposure toxicity space (CETS) model: Displaying exposure time, aqueous and organic concentration, activity, and onset of toxicity

    Science.gov (United States)

    Mackay, Donald; Parnis, J. Mark; McCarty, Lynn S.; Arnot, Jon A.; Powell, David E.

    2016-01-01

    Abstract A 1‐compartment toxicokinetic model is used to characterize the chemical exposure toxicity space (CETS), providing a novel graphic tool that can aid in the design of aquatic toxicity tests for fish and for interpreting their results. The graph depicts the solution to the differential equation describing the uptake kinetics of a chemical by a modeled fish under conventional bioassay conditions. The model relates the exposure concentration in the water to a dimensionless time and the onset of toxicity as determined by an estimated or assumed critical body residue or incipient lethal aqueous concentration. These concentration graphs are specific to each chemical and exposure and organism parameters and clearly demonstrate differences in toxicity between chemicals and how factors such as hydrophobicity influence the toxic endpoint. The CETS plots can also be used to assess bioconcentration test conditions to ensure that concentrations are well below toxic levels. Illustrative applications are presented using a recent set of high‐quality toxicity data. Conversion of concentrations to chemical activities in the plots enables results for different baseline toxicants to be superimposed. For chemicals that have different modes of toxic action, the increased toxicity then becomes apparent. Implications for design and interpretation of aquatic toxicity tests are discussed. The model, and pictorial visualization of the time‐course of aquatic toxicity tests, may contribute to improvements in test design, implementation, and interpretation, and to reduced animal usage. Environ Toxicol Chem 2017;36:1389–1396. © 2016 The Authors. Environmental Toxicology and Chemistry Published by Wiley Periodicals, Inc. on behalf of SETAC. PMID:27801500

  7. Clinical Voices - an update

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Weed, Ethan

    Anomalous aspects of speech and voice, including pitch, fluency, and voice quality, are reported to characterise many mental disorders. However, it has proven difficult to quantify and explain this oddness of speech by employing traditional statistical methods. In this talk we will show how the t...... the temporal dynamics of the voice in Asperger's patients enable us to automatically reconstruct the diagnosis, and assess the Autism quotient score. We then generalise the findings to Danish and American children with autism....

  8. The value of time-to-onset in statistical signal detection of adverse drug reactions : a comparison with disproportionality analysis in spontaneous reports from the Netherlands

    NARCIS (Netherlands)

    Scholl, Joep H G; van Puijenbroek, Eugène P

    2016-01-01

    PURPOSE: In pharmacovigilance, the commonly used disproportionality analysis (DPA) in statistical signal detection is known to have its limitations. The aim of this study was to investigate the value of the time to onset (TTO) of ADRs in addition to DPA. METHODS: We performed a pilot study using

  9. Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study

    DEFF Research Database (Denmark)

    Sørensen, Jette Led; Thranov, I; Hoff, G

    1994-01-01

    in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and...

  10. The value of time-to-onset in statistical signal detection of adverse drug reactions : a comparison with disproportionality analysis in spontaneous reports from the Netherlands

    NARCIS (Netherlands)

    Scholl, Joep H G; van Puijenbroek, Eugène P

    2016-01-01

    PURPOSE: In pharmacovigilance, the commonly used disproportionality analysis (DPA) in statistical signal detection is known to have its limitations. The aim of this study was to investigate the value of the time to onset (TTO) of ADRs in addition to DPA. METHODS: We performed a pilot study using ind

  11. CD163 macrophage and erythrocyte contents in aspirated deep vein thrombus are associated with the time after onset: a pilot study.

    Science.gov (United States)

    Furukoji, Eiji; Gi, Toshihiro; Yamashita, Atsushi; Moriguchi-Goto, Sayaka; Kojima, Mio; Sugita, Chihiro; Sakae, Tatefumi; Sato, Yuichiro; Hirai, Toshinori; Asada, Yujiro

    2016-01-01

    Thrombolytic therapy is effective in selected patients with deep vein thrombosis (DVT). Therefore, identification of a marker that reflects the age of thrombus is of particular concern. This pilot study aimed to identify a marker that reflects the time after onset in human aspirated DVT. We histologically and immunohistochemically analyzed 16 aspirated thrombi. The times from onset to aspiration ranged from 5 to 60 days (median of 13 days). Paraffin sections were stained with hematoxylin and eosin and antibodies for fibrin, glycophorin A, integrin α2bβ3, macrophage markers (CD68, CD163, and CD206), CD34, and smooth muscle actin (SMA). All thrombi were immunopositive for glycophorin A, fibrin, integrin α2bβ3, CD68, CD163, and CD206, and contained granulocytes. Almost all of the thrombi had small foci of CD34- or SMA-immunopositive areas. CD68- and CD163-immunopositive cell numbers were positively correlated with the time after onset, while the glycophorin A-immunopositive area was negatively correlated with the time after onset. In double immunohistochemistry, CD163-positive cells existed predominantly among the CD68-immunopositive macrophage population. CD163-positive macrophages were closely localized with glycophorin A, CD34, or SMA-positive cell-rich areas. These findings indicate that CD163 macrophage and erythrocyte contents could be markers for evaluation of the age of thrombus in DVT. Additionally, CD163 macrophages might play a role in organization of the process of venous thrombus.

  12. Single fixed-time artificial insemination in gilts and weaned sows using pLH at estrus onset administered through vulvar submucosal route.

    Science.gov (United States)

    Ulguim, R R; Fontana, D L; Bernardi, M L; Wentz, I; Bortolozzo, F P

    2016-09-01

    This study evaluated the use of a single fixed-time artificial insemination (FTAI) in gilts and weaned sows using 2.5 mg of porcine luteinizing hormone (pLH) administered through vulvar submucosal route, at the onset of estrus. In experiment 1 (Exp.1), 318 pubertal gilts were assigned to two groups: control-G-no hormonal application and artificial inseminations (AIs) at 12, 36, and 60 hours after the onset of estrus if they were still in standing estrus; and FTAI-G-use of pLH at the onset of estrus and a single FTAI 12 hours later. In experiment 2 (Exp. 2), 309 weaned sows were assigned to three groups: Control-S-no hormone application and AIs at 0, 24, and 48 hours after the onset of estrus if they were still in standing estrus; FTAI-NH-no hormone application and a single FTAI at 24 hours after the onset of estrus, and FTAI-pLH-use of pLH at the onset of estrus and a single FTAI 24 hours later. Transabdominal real time B-mode ultrasonography was performed to determine whether the insemination had been performed within 24 hours before ovulation, considered as the optimal interval. In Exp. 1, ultrasound evaluation (12-hour intervals) was carried out to determine the interval between the onset of estrus and ovulation. In both experiments, 2 × 10(9) sperm cells in 80 mL were used to perform cervical and postcervical deposition of semen in gilts and sows, respectively. Compared with control-G, FTAI-G gilts had shorter (P pLH: 88.0%) and TPB (Control-S: 12.8; FTAI-NH: 12.7, and FTAI-pLH: 12.0 piglets) among treatments. The presence of semen backflow reduced (P pLH and FTAI-NH sows. In the FTAI-pLH, a single insemination performed too late relative to ovulation reduced the AFR (P pLH applied at the vulvar submucosa at the onset of estrus advances the ovulation in gilts, but a single FTAI performed 12 hours later reduces the farrowing rate. A single FTAI performed at 24 hours after the onset of estrus in weaned sows does not affect their reproductive

  13. Effects of Medications on Voice

    Science.gov (United States)

    ... ENT Doctor Near You Effects of Medications on Voice Effects of Medications on Voice Patient Health Information ... entnet.org . Could Your Medication Be Affecting Your Voice? Some medications including prescription, over-the-counter, and ...

  14. A meta-analysis of potential relationship between Epstein-Barr-Encoded-RNA (EBER and onset time of post-transplant lymphoproliferative disorders

    Directory of Open Access Journals (Sweden)

    Hossein Khedmat

    2015-01-01

    Full Text Available Epstein-Barr virus (EBV encodes two non-polyadenylated RNAs termed EBV-encoded RNAs (EBERs. In this study, we tried to find series in which data of EBER and onset time of post-transplant lymphoproliferative disorder (PTLD for patients have been documented to conduct a meta-analysis. A comprehensive search of the literature was performed by Pubmed and Google scholar to find reports indicating test results for EBER and PTLD onset in transplant patients. PTLD was considered "early onset" when it develops within the first post-transplant year. Finally, 265 patients from 15 studies have been included in the meta-analysis. The overall meta-analysis also showed a significant relation between EBER test positivity and early-onset PTLD development [relative risk (RR: 1.36; 95% CI: 1.16-1.59; P <0.001]. The i2 index was 49.8%. Our study suggests that PTLD lesions with positive EBER test are more likely to develop within the early post-transplant period. Since early-onset PTLD is supposed to have better prognosis, having a positive EBER test might not be a bad news. However, for having a precise conclusion, prospective studies are needed to be conducted.

  15. Storage time of intraoperative transfused allogeneic red blood cells is not associated with new-onset postoperative atrial fibrillation in cardiac surgery

    DEFF Research Database (Denmark)

    Gu, Jiwei; Skals, Regitze Kuhr; Torp-Pedersen, Christian

    2017-01-01

    BACKGROUND: Allogeneic red blood cell (RBC) transfusion has been associated with new-onset postoperative atrial fibrillation (POAF) following cardiac surgery. Prolonged storage time of RBC may increase the risk. The primary aim of the study was to evaluate whether the storage time of RBC is assoc......BACKGROUND: Allogeneic red blood cell (RBC) transfusion has been associated with new-onset postoperative atrial fibrillation (POAF) following cardiac surgery. Prolonged storage time of RBC may increase the risk. The primary aim of the study was to evaluate whether the storage time of RBC...... is associated with development of POAF. MATERIALS AND METHODS: Pre-, per- and postoperative data were retrieved from the Western Denmark Heart Registry and local blood banks regarding patients who underwent coronary artery bypass surgery, valve surgery or combined procedures in Aalborg or Aarhus University...

  16. Once-daily indacaterol 75 µg in moderate- to-severe COPD: results of a Phase IV study assessing time until patients’ perceived onset of effect

    Directory of Open Access Journals (Sweden)

    Siler TM

    2014-09-01

    Full Text Available Thomas M Siler,1 Craig F LaForce,2 Farid Kianifard,3 James Williams,3 Selwyn Spangenthal4 1Midwest Chest Consultants, St Charles, MO, USA; 2North Carolina Clinical Research, Raleigh, NC, USA; 3Novartis Pharmaceuticals, East Hanover, NJ, USA; 4Charlotte Lung and Health Center, Charlotte, NC, USA Background: Indacaterol 75 µg once daily is a long-acting β2 agonist approved for maintenance bronchodilator treatment in patients with chronic obstructive pulmonary disease (COPD. The purpose of this study was to evaluate patients' perception of onset of effect with a single dose. Methods: In this double-blind, crossover, Phase IV study, 40 patients were randomized to receive a single dose of indacaterol 75 µg or placebo via a dry powder inhaler device. The primary variable was time until patient’s perception of onset of effect, using a simple self-administered (nonvalidated questionnaire that patients answered at nine protocol-specified time points. Exploratory variables included change in forced expiratory volume in 1 second (FEV1 and change in percent predicted FEV1 from predose to postdose (determined 60–75 minutes postdose. Results: The least-squares mean time to patient’s perception of onset of effect was 25.4 minutes and 23.9 minutes for indacaterol and placebo, respectively. There was no significant effect for treatment, period, or sequence on the time to patient's perception. In addition, no statistically significant differences between treatments were observed for patient's global satisfaction with onset of effect and global expectation of treatment adherence. For the exploratory variable change in FEV1 from predose to postdose, indacaterol showed superiority over placebo with a clinically relevant least-squares mean treatment difference of 0.12 L (P<0.0001. There was little or no association between patient’s perception of time to onset of effect and change in FEV1, or change in percent predicted FEV1. Both treatments were well

  17. Once-daily indacaterol 75 μg in moderate- to-severe COPD: results of a Phase IV study assessing time until patients' perceived onset of effect.

    Science.gov (United States)

    Siler, Thomas M; LaForce, Craig F; Kianifard, Farid; Williams, James; Spangenthal, Selwyn

    2014-01-01

    Indacaterol 75 μg once daily is a long-acting β2 agonist approved for maintenance bronchodilator treatment in patients with chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate patients' perception of onset of effect with a single dose. In this double-blind, crossover, Phase IV study, 40 patients were randomized to receive a single dose of indacaterol 75 μg or placebo via a dry powder inhaler device. The primary variable was time until patient's perception of onset of effect, using a simple self-administered (nonvalidated) questionnaire that patients answered at nine protocol-specified time points. Exploratory variables included change in forced expiratory volume in 1 second (FEV1) and change in percent predicted FEV1 from predose to postdose (determined 60-75 minutes postdose). The least-squares mean time to patient's perception of onset of effect was 25.4 minutes and 23.9 minutes for indacaterol and placebo, respectively. There was no significant effect for treatment, period, or sequence on the time to patient's perception. In addition, no statistically significant differences between treatments were observed for patient's global satisfaction with onset of effect and global expectation of treatment adherence. For the exploratory variable change in FEV1 from predose to postdose, indacaterol showed superiority over placebo with a clinically relevant least-squares mean treatment difference of 0.12 L (Pindacaterol 75 μg did not separate from placebo in terms of patient perception of onset, although there was an improvement in FEV1 for indacaterol compared with placebo. Development and use of a validated questionnaire may be needed to address the inconsistency in evaluating this patient-related outcome.

  18. Once-daily indacaterol 75 μg in moderate- to-severe COPD: results of a Phase IV study assessing time until patients’ perceived onset of effect

    Science.gov (United States)

    Siler, Thomas M; LaForce, Craig F; Kianifard, Farid; Williams, James; Spangenthal, Selwyn

    2014-01-01

    Background Indacaterol 75 μg once daily is a long-acting β2 agonist approved for maintenance bronchodilator treatment in patients with chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate patients’ perception of onset of effect with a single dose. Methods In this double-blind, crossover, Phase IV study, 40 patients were randomized to receive a single dose of indacaterol 75 μg or placebo via a dry powder inhaler device. The primary variable was time until patient’s perception of onset of effect, using a simple self-administered (nonvalidated) questionnaire that patients answered at nine protocol-specified time points. Exploratory variables included change in forced expiratory volume in 1 second (FEV1) and change in percent predicted FEV1 from predose to postdose (determined 60–75 minutes postdose). Results The least-squares mean time to patient’s perception of onset of effect was 25.4 minutes and 23.9 minutes for indacaterol and placebo, respectively. There was no significant effect for treatment, period, or sequence on the time to patient’s perception. In addition, no statistically significant differences between treatments were observed for patient’s global satisfaction with onset of effect and global expectation of treatment adherence. For the exploratory variable change in FEV1 from predose to postdose, indacaterol showed superiority over placebo with a clinically relevant least-squares mean treatment difference of 0.12 L (Pindacaterol 75 μg did not separate from placebo in terms of patient perception of onset, although there was an improvement in FEV1 for indacaterol compared with placebo. Development and use of a validated questionnaire may be needed to address the inconsistency in evaluating this patient-related outcome. PMID:25214778

  19. Voiced Reading and Rhythm

    Institute of Scientific and Technical Information of China (English)

    詹艳萍

    2007-01-01

    Since voiced reading is an important way in learning English,rhythm is the most critical factor that enables to read beautifully.This article illustrates the relationship between rhythm and voiced reading,the importance of rhythm,and the methods to develop the sense of rhythm.

  20. Clinical Voices - an update

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Weed, Ethan

    Anomalous aspects of speech and voice, including pitch, fluency, and voice quality, are reported to characterise many mental disorders. However, it has proven difficult to quantify and explain this oddness of speech by employing traditional statistical methods. In this talk we will show how...

  1. Borderline Space for Voice

    Science.gov (United States)

    Batchelor, Denise

    2012-01-01

    Being on the borderline as a student in higher education is not always negative, to do with marginalisation, exclusion and having a voice that is vulnerable. Paradoxically, being on the edge also has positive connections with integration, inclusion and having a voice that is strong. Alternative understandings of the concept of borderline space can…

  2. Voice and endocrinology

    Directory of Open Access Journals (Sweden)

    KVS Hari Kumar

    2016-01-01

    Full Text Available Voice is one of the advanced features of natural evolution that differentiates human beings from other primates. The human voice is capable of conveying the thoughts into spoken words along with a subtle emotion to the tone. This extraordinary character of the voice in expressing multiple emotions is the gift of God to the human beings and helps in effective interpersonal communication. Voice generation involves close interaction between cerebral signals and the peripheral apparatus consisting of the larynx, vocal cords, and trachea. The human voice is susceptible to the hormonal changes throughout life right from the puberty until senescence. Thyroid, gonadal and growth hormones have tremendous impact on the structure and function of the vocal apparatus. The alteration of voice is observed even in physiological states such as puberty and menstruation. Astute clinical observers make out the changes in the voice and refer the patients for endocrine evaluation. In this review, we shall discuss the hormonal influence on the voice apparatus in normal and endocrine disorders.

  3. Face the voice

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2014-01-01

    will be based on a reception aesthetic and phenomenological approach, the latter as presented by Don Ihde in his book Listening and Voice. Phenomenologies of Sound , and my analytical sketches will be related to theoretical statements concerning the understanding of voice and media (Cavarero, Dolar, La...

  4. Voice integrated systems

    Science.gov (United States)

    Curran, P. Mike

    1977-01-01

    The program at Naval Air Development Center was initiated to determine the desirability of interactive voice systems for use in airborne weapon systems crew stations. A voice recognition and synthesis system (VRAS) was developed and incorporated into a human centrifuge. The speech recognition aspect of VRAS was developed using a voice command system (VCS) developed by Scope Electronics. The speech synthesis capability was supplied by a Votrax, VS-5, speech synthesis unit built by Vocal Interface. The effects of simulated flight on automatic speech recognition were determined by repeated trials in the VRAS-equipped centrifuge. The relationship of vibration, G, O2 mask, mission duration, and cockpit temperature and voice quality was determined. The results showed that: (1) voice quality degrades after 0.5 hours with an O2 mask; (2) voice quality degrades under high vibration; and (3) voice quality degrades under high levels of G. The voice quality studies are summarized. These results were obtained with a baseline of 80 percent recognition accuracy with VCS.

  5. Ontario's Student Voice Initiative

    Science.gov (United States)

    Courtney, Jean

    2014-01-01

    This article describes in some detail aspects of the Student Voice initiative funded and championed by Ontario's Ministry of Education since 2008. The project enables thousands of students to make their voices heard in meaningful ways and to participate in student-led research. Some students from grades 7 to 12 become members of the Student…

  6. An Implementation of Mobile Wireless Ad Hoc Real-time Voice Communication System%一种移动无线自组网即时语音通信系统的实现

    Institute of Scientific and Technical Information of China (English)

    李现涛; 郭达伟; 李杨

    2011-01-01

    Mobile Ad Hoc has been quickly developed recently, requirement for real - time voice communication based on the platform is increasingly shown. This paper gives out a way to realize the multi - hop real - time voice communication system, with the technology VOIP, RTP and so on. Through mobile tests, the system has shown a good performance,which is sentenced to be more than 3.5 by MOS standard under low speed mobile condition, this system could support instant voice communication.%近年来,移动无线自组织网络迅速发展,在该平台上实时语音通信的需求也日益显现.在linux平台下,利用VOIP和RTP等技术实现了无线移动自组织网络的多跳即时语音通信系统.并通过上网本组成的硬件实验平台进行了移动实验,在低速移动条件下的实时语音通信效果MOS评分在3.5以上,能够满足即时语音通信的需求.

  7. EasyVoice: Integrating voice synthesis with Skype

    CERN Document Server

    Condado, Paulo A

    2007-01-01

    This paper presents EasyVoice, a system that integrates voice synthesis with Skype. EasyVoice allows a person with voice disabilities to talk with another person located anywhere in the world, removing an important obstacle that affect these people during a phone or VoIP-based conversation.

  8. Time-frequency relationships between heart rate and respiration: A diagnosis tool for late onset sepsis in sick premature infants

    OpenAIRE

    Carrault, Guy; Beuchée, Alain; Pladys, Patrick; Senhadji, Lotfi; Hernandez, Alfredo

    2009-01-01

    International audience; The diagnosis of late onset sepsis in premature infants remains difficult because clinical signs are subtle and non-specific and none of the laboratory tests, including CRP and blood culture, have high predictive accuracy. Heart rate variability (HRV) analysis emerges as a promising diagnostic tool. Entropy and long-range fractal correlation are decreased in premature infants with proven sepsis. Besides this, respiration and its relations to HRV appear to be less. The ...

  9. Neural mechanisms for voice recognition

    NARCIS (Netherlands)

    Andics, A.V.; McQueen, J.M.; Petersson, K.M.; Gal, V.; Rudas, G.; Vidnyanszky, Z.

    2010-01-01

    We investigated neural mechanisms that support voice recognition in a training paradigm with fMRI. The same listeners were trained on different weeks to categorize the mid-regions of voice-morph continua as an individual's voice. Stimuli implicitly defined a voice-acoustics space, and training expli

  10. Baseline Q waves and time from symptom onset to ST-segment elevation myocardial infarction: insights from PLATO on the influence of sex.

    Science.gov (United States)

    Kholaif, Naji; Zheng, Yinggan; Jagasia, Pushpa; Himmelmann, Anders; James, Stefan K; Steg, Philippe Gabriel; Storey, Robert F; Westerhout, Cynthia M; Armstrong, Paul W

    2015-08-01

    The prognostic value of time from symptom onset to reperfusion may be enhanced by the identification of Q waves on the presenting electrocardiogram (ECG) in patients with ST-segment elevation myocardial infarction (STEMI). We evaluated whether the relative prognostic utility of these 2 metrics was altered by sex. Q waves in the distribution of the ST-segment elevation on the baseline ECG were evaluated by a blinded core laboratory in 2838 STEMI patients (2163 men and 675 women) from the PLATelet inhibition and patient Outcomes (PLATO) trial who underwent percutaneous coronary intervention (PCI) within 12 hours of symptom onset. Women were older (median 63 vs 57 years), more likely to be diabetic (24.1% vs 15.5%), hypertensive (69.2% vs 50.9%), and a higher Killip class > I (8.6% vs 5.9%), as compared with men. Whereas the Q waves frequency rose progressively over time to ECG in men, this relationship was attenuated in women (P = .057). Q waves on the baseline ECG were associated with a higher excess hazard of 1-year vascular death in men (hazard ratio [HR] 2.03; 95% confidence interval [CI], 1.13-3.72), and a similar trend existed in women (HR 1.97; 95% CI, 0.86-4.51). Women with baseline Q waves tended to have higher risk of 1-year vascular death than men as continuous time from symptom onset to PCI increased (P[interaction] = .182). These differences in the evolution of baseline Q waves and relationship between time from symptom onset and vascular death in women and men deserve recognition in future studies of STEMI. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Differences in onset timing between the vastus medialis and lateralis during concentric knee contraction in individuals with genu varum or valgum.

    Science.gov (United States)

    Park, Seol; Kong, Yong-Soo; Ko, Yu-Min; Jang, Gwon-Uk; Park, Ji-Won

    2015-04-01

    [Purpose] The purpose of this study was to investigate the difference in onset timing between the vastus medialis and lateralis among the different knee alignments, as well as the best isokinetic angular velocity for an isokinetic concentric contraction. [Subjects] Fifty-two adults (20 with genu varum, 12 genu valgum, and 20 controls) were enrolled in this study. Subjects with > 4 cm between the medial epicondyles of the knee were placed in the genu varum group, whereas subjects with > 4 cm between the medial malleolus of the ankle were placed in the genu valgum group. [Methods] Surface electromyography was used to measure the onset times of the vastus medialis and vastus lateralis during concentric contractions at 30, 60, and 90°/sec. [Results] The vastus lateralis showed more delayed firing than the vastus medialis in the genu varum group, whereas vastus medialis firing was delayed more than that of the vastus lateralis in the genu valgum group. No differences in onset timing were observed between the vastus medialis and lateralis according the different angular velocities during concentric contractions in all three groups. [Conclusion] Genu varum and valgum affect quadriceps firing. Therefore, selective rehabilitation training of the quadriceps femoris should be considered to prevent pain or knee malalignment deformities.

  12. Dominant Voice in Hamlet

    Institute of Scientific and Technical Information of China (English)

    李丹

    2015-01-01

    <正>The Tragedy of Hamlet dramatizes the revenge Prince Hamlet exacts on his uncle Claudius for murdering King Hamlet,Claudius’s brother and Prince Hamlet’s father,and then succeeding to the throne and taking as his wife Gertrude,the old king’s widow and Prince Hamlet’s mother.This paper will discuss something about dominant voice in the play.Dominant voice is the major voice in the country,the society,or the whole world.Those people who have the power or

  13. METHODS FOR QUALITY ENHANCEMENT OF USER VOICE SIGNAL IN VOICE AUTHENTICATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    O. N. Faizulaieva

    2014-03-01

    Full Text Available The reasonability for the usage of computer systems user voice in the authentication process is proved. The scientific task for improving the signal/noise ratio of the user voice signal in the authentication system is considered. The object of study is the process of input and output of the voice signal of authentication system user in computer systems and networks. Methods and means for input and extraction of voice signal against external interference signals are researched. Methods for quality enhancement of user voice signal in voice authentication systems are suggested. As modern computer facilities, including mobile ones, have two-channel audio card, the usage of two microphones is proposed in the voice signal input system of authentication system. Meanwhile, the task of forming a lobe of microphone array in a desired area of voice signal registration (100 Hz to 8 kHz is solved. The usage of directional properties of the proposed microphone array gives the possibility to have the influence of external interference signals two or three times less in the frequency range from 4 to 8 kHz. The possibilities for implementation of space-time processing of the recorded signals using constant and adaptive weighting factors are investigated. The simulation results of the proposed system for input and extraction of signals during digital processing of narrowband signals are presented. The proposed solutions make it possible to improve the value of the signal/noise ratio of the useful signals recorded up to 10, ..., 20 dB under the influence of external interference signals in the frequency range from 4 to 8 kHz. The results may be useful to specialists working in the field of voice recognition and speaker’s discrimination.

  14. Secure voice-based authentication for mobile devices: vaulted voice verification

    Science.gov (United States)

    Johnson, R. C.; Scheirer, Walter J.; Boult, Terrance E.

    2013-05-01

    As the use of biometrics becomes more wide-spread, the privacy concerns that stem from the use of biometrics are becoming more apparent. As the usage of mobile devices grows, so does the desire to implement biometric identification into such devices. A large majority of mobile devices being used are mobile phones. While work is being done to implement different types of biometrics into mobile phones, such as photo based biometrics, voice is a more natural choice. The idea of voice as a biometric identifier has been around a long time. One of the major concerns with using voice as an identifier is the instability of voice. We have developed a protocol that addresses those instabilities and preserves privacy. This paper describes a novel protocol that allows a user to authenticate using voice on a mobile/remote device without compromising their privacy. We first discuss the Vaulted Verification protocol, which has recently been introduced in research literature, and then describe its limitations. We then introduce a novel adaptation and extension of the Vaulted Verification protocol to voice, dubbed Vaulted Voice Verification (V3). Following that we show a performance evaluation and then conclude with a discussion of security and future work.

  15. Comparison of Voice Perceptual Charactheristics between Speech - Language Pathologists', Dysphonic and Normal Voiced Adult's View

    Directory of Open Access Journals (Sweden)

    Seyyedeh Maryam khoddami

    2010-06-01

    Full Text Available Background and Aim: In recent years, several tools for assessment of quality of patient life have been designed especially for dysphonics. Nowadays, we have useful assessments in health system that are refered for numerous clinical decisions. In this way, this investigation compares clinician and patient perception in dysphonic and normal voiced for first time.Methods: This study was carried out on 30 dysphonic and 30 subjects with normal voice. Their age, sex and job were same. In two groups, Consensus Auditory – Perceptual Evaluation of Voice (CAPE-V was used for evaluation of clinician perception and Voice Handicap Index - 30 (VHI-30 for assessment of patient perception. After collecting data, they were analyzed by Mann- witney and Wilcoxon tests.Results: The research revealed that mean of total and each section score of VHI-30 have significant difference between dysphonic and control group (p<0.01. Comparison of total and every parameter score of CAPE-V and speed also indicated significant difference between two groups (p<0.01. Study of reliability shows weak reliability (r=0.34 between clinician and patient perception of voice in dysphonics.Conclusion: Dysphonic patients percept their voice problem different and severe rather than clinicians that shows physical, psychological and social affects of dysphonia. This research confirms that patient – based assessment of voice is necessary to be part of common assessments of dysphonia.

  16. Time-to-Onset Analysis of Drug-Induced Long QT Syndrome Based on a Spontaneous Reporting System for Adverse Drug Events

    Science.gov (United States)

    Sasaoka, Sayaka; Matsui, Toshinobu; Hane, Yuuki; Abe, Junko; Ueda, Natsumi; Motooka, Yumi; Hatahira, Haruna; Fukuda, Akiho; Naganuma, Misa; Hasegawa, Shiori; Kinosada, Yasutomi

    2016-01-01

    Long QT syndrome (LQTS) is a disorder of the heart’s electrical activity that infrequently causes severe ventricular arrhythmias such as a type of ventricular tachycardia called torsade de pointes (TdP) and ventricular fibrillation, which can be fatal. There have been no previous reports on the time-to-onset for LQTS based on data from spontaneous reporting systems. The aim of this study was to assess the time-to-onset of LQTS according to drug treatment. We analyzed the association between 113 drugs in 37 therapeutic categories and LQTS including TdP using data obtained from the Japanese Adverse Drug Event Report database. For signal detection, we used the reporting odds ratio (ROR). Furthermore, we analyzed the time-to-onset data and assessed the hazard type using the Weibull shape parameter. The RORs (95% confidence interval) for bepridil, amiodarone, pilsicainide, nilotinib, disopyramide, arsenic trioxide, clarithromycin, cibenzoline, donepezil, famotidine, sulpiride, and nifekalant were 174.4 (148.6–204.6), 17.3 (14.7–20.4), 52.0 (43.4–62.4), 13.9 (11.5–16.7), 69.3 (55.3–86.8), 54.2 (43.2–68.0), 4.7 (3.8–5.8), 19.9 (15.9–25.0), 8.1 (6.5–10.1), 3.2 (2.5–4.1), 7.1 (5.5–9.2), and 254.8 (168.5–385.4), respectively. The medians and quartiles of time-to-onset for aprindine (oral) and bepridil were 20.0 (11.0–35.8) and 18.0 (6.0–43.0) days, respectively. The lower 95% confidence interval of the shape parameter β of bepridil was over 1 and the hazard was considered to increase over time.Our study indicated that the pattern of LQTS onset might differ among drugs. Based on these results, careful long-term observation is recommended, especially for specific drugs such as bepridil and aprindine. This information may be useful for the prevention of sudden death following LQTS and for efficient therapeutic planning. PMID:27723808

  17. Speech therapist led voice clinic: which patients may be suitable?

    Science.gov (United States)

    Vaghela, Hersad M; Fergie, Neil; Slade, Suzanne; McGlashan, Julian A

    2005-01-01

    Joint Voice clinics run by an ENT surgeon (Laryngologist) and Voice therapist avoid repetition of clinical assessment, better planning of patient management and early initiation of treatment. Although is perceived as optimal management of voice patients it is perhaps not necessary for all patients as it is time consuming for the clinicians involved. The aim of this study was to investigate whether it was possible to identify any subgroup of patients that could potentially be seen in a Voice therapist-led new patient clinic by reviewing the outcome of 96 patients referred to a Joint Voice clinic. Forty-four patients were referred for voice therapy out of which 13 (30%) were teachers or lecturers (total number: 16 (81%)). Two others in this subgroup required medical treatment and the other surgery. The most common aetiology in these professional voice users was muscle tension dysphonia (10 patients, 63%). It is concluded that experienced Voice therapists appropriately trained in laryngostroboscopic assessment could potentially receive and manage direct referrals from primary care physicians. They should however work as part of a multi-professional Voice Disorders Team where the patients could be reviewed by an ENT surgeon if necessary. This would significantly improve the patient pathway for these patients, be cost-effective and make the best use of therapist's and ENT surgeon's time.

  18. Caracterização acústica da sonoridade dos fones plosivos do português brasileiro Acoustic characterization of the voicing of plosives phones in Brazilian Portuguese

    Directory of Open Access Journals (Sweden)

    Roberta Michelon Melo

    2011-01-01

    Full Text Available OBJETIVO: investigar e comparar as características acústicas das plosivas surdas e sonoras na fala de crianças com desenvolvimento fonológico típico e, de adultos com padrões de fala típicos da língua. MÉTODO: a amostra do estudo é composta por dois grupos - 17 adultos e 11 crianças com desenvolvimento fonológico típico. Por meio de palavras/pseudopalavras (['papa], ['baba], ['tata], ['dada], ['kaka] e ['gaga] inseridas em frases-veículo ("Fala ___ papa de novo", mediu-se o voice onset time, a duração da vogal, a amplitude do burst e a duração da oclusão. Foram comparados os registros acústicos de plosivas surdas e sonoras intra e intergrupo por meio de testes estatísticos (pPURPOSE: to investigate and compare the acoustic characteristics of voiceless and voiced plosives in the speech of children with typical phonological development and adults with typical language speech patterns. METHOD: the study's sample is arranged in two groups - 17 adults and 11 children with typical phonological development. Through words/pseudowords (['papa], ['baba], ['tata], ['dada], ['kaka] and ['gaga] inserted into carrier phrases ("Say ___ papa again", the voice onset time, the length of the vowel, and we measured the burst amplitude and the length of the occlusion. The acoustic records of voiceless and voiced plosives intragroup and intergroup were compared through statistical tests (p<0.05. RESULTS: in general, the results suggest that: (1 the voice onset time was longer for voiced plosives when compared to the voiceless plosives; (2 the vowel length when followed or preceded by a voiced plosive was longer than in front of a voiceless plosive; (3 the burst amplitude was slightly superior during the production of voiced segments and; (4 the length of the occlusion was superior in the context of voiceless plosives. Furthermore, the adults and children showed many similarities related to the production of these parameters. CONCLUSION: the

  19. Ethnographic Voice Memo Narratives

    DEFF Research Database (Denmark)

    Rasmussen, Mette Apollo; Conradsen, Maria Bosse

    1800-01-01

    -based technique which actively involves actors in producing ethnography-based data concerning their everyday practice. With the help from smartphone technology it is possible to complement ethnography-based research methods when involving the actors and having them create small voice memo narratives. The voice...... memos create insights of actors‟ everyday practice, without the direct presence of a researcher and could be considered a step towards meeting the dilemmas of research in complex fieldwork settings....

  20. Voice disorders in mucosal leishmaniasis.

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    Ana Cristina Nunes Ruas

    Full Text Available INTRODUCTION: Leishmaniasis is considered as one of the six most important infectious diseases because of its high detection coefficient and ability to produce deformities. In most cases, mucosal leishmaniasis (ML occurs as a consequence of cutaneous leishmaniasis. If left untreated, mucosal lesions can leave sequelae, interfering in the swallowing, breathing, voice and speech processes and requiring rehabilitation. OBJECTIVE: To describe the anatomical characteristics and voice quality of ML patients. MATERIALS AND METHODS: A descriptive transversal study was conducted in a cohort of ML patients treated at the Laboratory for Leishmaniasis Surveillance of the Evandro Chagas National Institute of Infectious Diseases-Fiocruz, between 2010 and 2013. The patients were submitted to otorhinolaryngologic clinical examination by endoscopy of the upper airways and digestive tract and to speech-language assessment through directed anamnesis, auditory perception, phonation times and vocal acoustic analysis. The variables of interest were epidemiologic (sex and age and clinic (lesion location, associated symptoms and voice quality. RESULTS: 26 patients under ML treatment and monitored by speech therapists were studied. 21 (81% were male and five (19% female, with ages ranging from 15 to 78 years (54.5+15.0 years. The lesions were distributed in the following structures 88.5% nasal, 38.5% oral, 34.6% pharyngeal and 19.2% laryngeal, with some patients presenting lesions in more than one anatomic site. The main complaint was nasal obstruction (73.1%, followed by dysphonia (38.5%, odynophagia (30.8% and dysphagia (26.9%. 23 patients (84.6% presented voice quality perturbations. Dysphonia was significantly associated to lesions in the larynx, pharynx and oral cavity. CONCLUSION: We observed that vocal quality perturbations are frequent in patients with mucosal leishmaniasis, even without laryngeal lesions; they are probably associated to disorders of some

  1. Reading aloud in Persian: ERP evidence for an early locus of the masked onset priming effect.

    Science.gov (United States)

    Timmer, Kalinka; Vahid-Gharavi, Narges; Schiller, Niels O

    2012-07-01

    The current study investigates reading aloud words in Persian, a language that does not mark all its vowels in the script. Behaviorally, a masked onset priming effect (MOPE) was revealed for transparent words, with faster speech onset latencies in the phoneme-matching condition (i.e. phonological prime and target onset overlap; e.g. [symbol: see text] /sɒːl/; 'year' [symbol: see text] /sot/; 'voice') than the phoneme-mismatching condition (e.g. [symbol: see text] /tɒːb/ 'swing' - [symbol: see text] /sot/; 'voice'). For opaque target words (e.g. [symbol: see text] /solh/; 'peace'), no such effect was found. However, event-related potentials (ERPs) did reveal an amplitude difference between the two prime conditions in the 80-160 ms time window for transparent as well as opaque words. Only for the former, this effect continued into the 300-480 ms time window. This finding constrains the time course of the MOPE and suggests the simultaneous activation of both the non-lexical grapheme-to-phoneme and the lexical route in the dual-route cascaded (DRC) model. Copyright © 2012 Elsevier Inc. All rights reserved.

  2. Association between birth control pills and voice quality.

    Science.gov (United States)

    Amir, Ofer; Kishon-Rabin, Liat

    2004-06-01

    The objective was to extend our knowledge of the effect of birth control pills on voice quality in women based on various acoustic measures. A longitudinal comparative study of 14 healthy young women over a 36- to 45-day period. Voices of seven women who used birth control pills and seven women who did not were recorded repeatedly approximately 20 times. Voice samples were analyzed acoustically, using an extended set of frequency perturbation parameters (jitter, relative average perturbation, pitch period perturbation quotient), amplitude perturbation parameters (shimmer, amplitude average perturbation quotient), and noise indices (noise-to-harmonics ratio, voice turbulence index). Voice quality and stability were found to be better among the women who used birth control pills. Lower values were found for all acoustic measures with the exception of voice turbulence index. Results also provided preliminary indication for vocal changes associated with the days preceding ovulation. In contrast to the traditional view of oral contraceptives as a risk factor for voice quality, and in keeping with the authors' previous work, the data in the present study showed that not only did oral contraceptives have no adverse effect on voice quality but, in effect, most acoustic measures showed improved voice quality among women who used the birth control pill. The differences in the noise indices between groups may also shed light on the nature of the effect of sex hormones on vocal fold activity. It was suggested that hormonal fluctuations may have more of an effect on vocal fold regulation of vibration than on glottal adduction.

  3. Seizure-Onset Mapping Based on Time-Variant Multivariate Functional Connectivity Analysis of High-Dimensional Intracranial EEG: A Kalman Filter Approach.

    Science.gov (United States)

    Lie, Octavian V; van Mierlo, Pieter

    2017-01-01

    The visual interpretation of intracranial EEG (iEEG) is the standard method used in complex epilepsy surgery cases to map the regions of seizure onset targeted for resection. Still, visual iEEG analysis is labor-intensive and biased due to interpreter dependency. Multivariate parametric functional connectivity measures using adaptive autoregressive (AR) modeling of the iEEG signals based on the Kalman filter algorithm have been used successfully to localize the electrographic seizure onsets. Due to their high computational cost, these methods have been applied to a limited number of iEEG time-series (theory index of outward directed connectivity. Simulation results indicated high levels of mapping accuracy for the two models in the presence of low-to-moderate noise cross-correlation. Accordingly, both AR models correctly mapped the real seizure onset to the resection volume. This study supports the possibility of conducting fully data-driven multivariate connectivity estimations on high-dimensional iEEG datasets using the Kalman filter approach.

  4. Exit and voice in dutch social health insurance.

    NARCIS (Netherlands)

    Gress, S.; Delnoij, D.; Groenewegen, P.P.

    2003-01-01

    According to Hirschmann's concept of exit and voice, people have two options to make sure that firms or organisations realise what they (their consumers or members) are interested in (Hirschmann 1970). In the Dutch public health insurance system voice existed for a long time, but exit was only intro

  5. Trading of dynamic interaural time and level difference cues and its effect on the auditory motion-onset response measured with electroencephalography.

    Science.gov (United States)

    Altmann, Christian F; Ueda, Ryuhei; Bucher, Benoit; Furukawa, Shigeto; Ono, Kentaro; Kashino, Makio; Mima, Tatsuya; Fukuyama, Hidenao

    2017-07-27

    Interaural time (ITD) and level differences (ILD) constitute the two main cues for sound localization in the horizontal plane. Despite extensive research in animal models and humans, the mechanism of how these two cues are integrated into a unified percept is still far from clear. In this study, our aim was to test with human electroencephalography (EEG) whether integration of dynamic ITD and ILD cues is reflected in the so-called motion-onset response (MOR), an evoked potential elicited by moving sound sources. To this end, ITD and ILD trajectories were determined individually by cue trading psychophysics. We then measured EEG while subjects were presented with either static click-trains or click-trains that contained a dynamic portion at the end. The dynamic part was created by combining ITD with ILD either congruently to elicit the percept of a right/leftward moving sound, or incongruently to elicit the percept of a static sound. In two experiments that differed in the method to derive individual dynamic cue trading stimuli, we observed an MOR with at least a change-N1 (cN1) component for both the congruent and incongruent conditions at about 160-190 ms after motion-onset. A significant change-P2 (cP2) component for both the congruent and incongruent ITD/ILD combination was found only in the second experiment peaking at about 250 ms after motion onset. In sum, this study shows that a sound which - by a combination of counter-balanced ITD and ILD cues - induces a static percept can still elicit a motion-onset response, indicative of independent ITD and ILD processing at the level of the MOR - a component that has been proposed to be, at least partly, generated in non-primary auditory cortex. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Time prediction of an onset of shallow landslides based on the monitoring of the groundwater level and the surface displacement at different locations on a sandy model slope

    Science.gov (United States)

    Sasahara, Katsuo

    2016-04-01

    Location of monitoring of the deformation and the groundwater level in a slope is important for time-prediction of an onset of shallow landslides based on the monitoring. The analysis of the monitored data of the surface displacement and the groundwater level at different locations in sandy model slope under artificial rainfall was conducted in this study. The monitored data showed that the surface displacement increased with the increase of the groundwater level significantly. Then the analysis of the monitored data revealed that the relation between the surface displacement and the groundwater level can be modified as hyperbolic curve. The surface displacement grew larger and maximum groundwater level was smaller at farther location from the toe of the slope. Time-prediction of an onset of a landslide based on the monitored data at different location on the slope was proposed as following procedures. (1) To make a regression equation for the relation between the surface displacement and the groundwater level based on the monitored data at any time before the failure, (2) To make a regression equation for the relation between the time and the groundwater level based on the same data with (1), and (3) To incorporate the equation for the relation between the time and the groundwater level into that between the surface displacement and the groundwater level to derive the time - the surface displacement relation. (4) To derive the time - the inverse of the surface displacement velocity from the equation for the time - the surface displacement relation. The equation for the time - the surface displacement and the equation for the time - the inverse of the surface displacement velocity could simulate the actual phenomena of the slope well based on the monitored data at any location on the model slope.

  7. Hear today, not gone tomorrow? An exploratory longitudinal study of auditory verbal hallucinations (hearing voices).

    Science.gov (United States)

    Hartigan, Nicky; McCarthy-Jones, Simon; Hayward, Mark

    2014-01-01

    Despite an increasing volume of cross-sectional work on auditory verbal hallucinations (hearing voices), there remains a paucity of work on how the experience may change over time. The first aim of this study was to attempt replication of a previous finding that beliefs about voices are enduring and stable, irrespective of changes in the severity of voices, and do not change without a specific intervention. The second aim was to examine whether voice-hearers' interrelations with their voices change over time, without a specific intervention. A 12-month longitudinal examination of these aspects of voices was undertaken with hearers in routine clinical treatment (N = 18). We found beliefs about voices' omnipotence and malevolence were stable over a 12-month period, as were styles of interrelating between voice and hearer, despite trends towards reductions in voice-related distress and disruption. However, there was a trend for beliefs about the benevolence of voices to decrease over time. Styles of interrelating between voice and hearer appear relatively stable and enduring, as are beliefs about the voices' malevolent intent and power. Although there was some evidence that beliefs about benevolence may reduce over time, the reasons for this were not clear. Our exploratory study was limited by only being powered to detect large effect sizes. Implications for clinical practice and future research are discussed.

  8. The indwelling voice prosthesis for speech rehabilitation after total laryngectomy: a safe approach

    NARCIS (Netherlands)

    Balm, A.J.M.; van den Brekel, M.W.M.; Tan, I.B.; Hilgers, F.J.M.

    2011-01-01

    Primary prosthetic voice restoration by performing tracheoesophageal puncture (TEP) and immediate insertion of a voice prosthesis at the time of total laryngectomy (TLE) is presently the method of choice. This enables the easiest and most comfortable voice rehabilitation with the patient still under

  9. Early psychological intervention for auditory hallucinations: an exploratory study of young people's voices groups.

    Science.gov (United States)

    Newton, Elizabeth; Landau, Sabine; Smith, Patrick; Monks, Paul; Shergill, Sukhi; Wykes, Til

    2005-01-01

    Twenty to fifty percent of people with a diagnosis of schizophrenia continue to hear voices despite taking neuroleptic medication. Trials of group cognitive behavioral therapy for adults with auditory hallucinations have shown promising results. Auditory hallucinations may be most amenable to psychological intervention during a 3-year critical period after symptom onset. This study evaluates the effectiveness of group cognitive behavioral therapy (CBT) for young people with recent-onset auditory hallucinations (N = 22), using a waiting list control. Outcome measures were administered at four separate time points. Significant reductions in auditory hallucinations occurred over the total treatment phase, but not over the waiting period. Further investigations in the form of randomized controlled trials are warranted.

  10. Voice Matching Using Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Abhishek Bal

    2014-03-01

    Full Text Available In this paper, the use of Genetic Algorithm (GA for voice recognition is described. The practical application of Genetic Algorithm (GA to the solution of engineering problem is a rapidly emerging approach in the field of control engineering and signal processing. Genetic algorithms are useful for searching a space in multi-directional way from large spaces and poorly defined space. Voice is a signal of infinite information. Digital processing of voice signal is very important for automatic voice recognition technology. Nowadays, voice processing is very much important in security mechanism due to mimicry characteristic. So studying the voice feature extraction in voice processing is very necessary in military, hospital, telephone system, investigation bureau and etc. In order to extract valuable information from the voice signal, make decisions on the process, and obtain results, the data needs to be manipulated and analyzed. In this paper, if the instant voice is not matched with same person’s reference voices in the database, then Genetic Algorithm (GA is applied between two randomly chosen reference voices. Again the instant voice is compared with the result of Genetic Algorithm (GA which is used, including its three main steps: selection, crossover and mutation. We illustrate our approach with different sample of voices from human in our institution.

  11. Voice Therapy Practices and Techniques: A Survey of Voice Clinicians.

    Science.gov (United States)

    Mueller, Peter B.; Larson, George W.

    1992-01-01

    Eighty-three voice disorder therapists' ratings of statements regarding voice therapy practices indicated that vocal nodules are the most frequent disorder treated; vocal abuse and hard glottal attack elimination, counseling, and relaxation were preferred treatment approaches; and voice therapy is more effective with adults than with children.…

  12. Voice in early glottic cancer compared to benign voice pathology

    NARCIS (Netherlands)

    Van Gogh, C. D. L.; Mahieu, H. F.; Kuik, D. J.; Rinkel, R. N. P. M.; Langendijk, J. A.; Verdonck-de Leeuw, I. M.

    2007-01-01

    The purpose of this study is to compare (Dutch) Voice Handicap Index (VHIvumc) scores from a selected group of patients with voice problems after treatment for early glottic cancer with patients with benign voice disorders and subjects from the normal population. The study included a group of 35 pat

  13. Psychogenic voice disorders and traumatic stress experience: a discussion paper with two case reports.

    Science.gov (United States)

    Baker, Janet

    2003-09-01

    Psychogenic dysphonia refers to loss of voice where there is insufficient structural or neurological pathology to account for the nature and severity of the dysphonia, and where loss of volitional control over phonation seems to be related to psychological processes such as anxiety, depression, conversion reaction, or personality disorder. Such dysphonias may often develop post-viral infection with laryngitis, and generally in close proximity to emotionally or psychologically taxing experiences, where "conflict over speaking out" is an issue. In more rare instances, severe and persistent psychogenic dysphonia may develop under innocuous or unrelated circumstances, but over time, it may be traced back to traumatic stress experiences that occurred many months or years prior to the onset of the voice disorder. In such cases, the qualitative nature of the traumatic experience may be reflected in the way the psychogenic voice disorder presents. The possible relationship between psychogenic dysphonia and earlier traumatic stress experience is discussed, and the reportedly low prevalence of conversion reaction (4% to 5%) as the basis for psychogenic dysphonia is challenged. Two cases are presented to illustrate the issues raised: the first, a young woman who was sexually assaulted and chose to "keep her secret," and the second, a 52-year-old woman who developed a psychogenic dysphonia following a second, modified thyroplasty for a unilateral vocal fold paresis.

  14. The inner voice

    Directory of Open Access Journals (Sweden)

    Anthony James Ridgway

    2009-12-01

    Full Text Available The inner voice- we all know what it is because we all have it and use it when we are thinking or reading, for example. Little work has been done on it in our field, with the notable exception of Brian Tomlinson, but presumably it must be a cognitive phenomenon which is of great importance in thinking, language learning, and reading in a foreign language. The inner voice will be discussed as a cognitive psychological phenomenon associated with short-term memory, and distinguished from the inner ear. The process of speech recoding will be examined (the process of converting written language into the inner voice and the importance of developing the inner voice, as a means of both facilitating the production of a new language and enhancing the comprehension of a text in a foreign language, will be emphasized. Finally, ways of developing the inner voice in beginning and intermediate readers of a foreign language will be explored and recommended.

  15. Smartphone App for Voice Disorders

    Science.gov (United States)

    ... on. Feature: Taste, Smell, Hearing, Language, Voice, Balance Smartphone App for Voice Disorders Past Issues / Fall 2013 ... developed a mobile monitoring device that relies on smartphone technology to gather a week's worth of talking, ...

  16. Onset dominance in lateralization.

    Science.gov (United States)

    Freyman, R L; Zurek, P M; Balakrishnan, U; Chiang, Y C

    1997-03-01

    Saberi and Perrott [Acustica 81, 272-275 (1995)] found that the in-head lateralization of a relatively long-duration pulse train could be controlled by the interaural delay of the single pulse pair that occurs at onset. The present study examined this further, using an acoustic pointer measure of lateralization, with stimulus manipulations designed to determine conditions under which lateralization was consistent with the interaural onset delay. The present stimuli were wideband pulse trains, noise-burst trains, and inharmonic complexes, 250 ms in duration, chosen for the ease with which interaural delays and correlations of select temporal segments of the stimulus could be manipulated. The stimulus factors studied were the periodicity of the ongoing part of the signal as well as the multiplicity and ambiguity of interaural delays. The results, in general, showed that the interaural onset delay controlled lateralization when the steady state binaural cues were relatively weak, either because the spectral components were only sparsely distributed across frequency or because the interaural time delays were ambiguous. Onset dominance can be disrupted by sudden stimulus changes within the train, and several examples of such changes are described. Individual subjects showed strong left-right asymmetries in onset effectiveness. The results have implications for understanding how onset and ongoing interaural delay cues contribute to the location estimates formed by the binaural auditory system.

  17. Early Onset Werner Syndrome

    Directory of Open Access Journals (Sweden)

    Berna İmge Aydoğan

    2015-09-01

    Full Text Available Werner syndrome (WS is a rare autosomal recessive adult-onset progeroid disorder characterized by the early onset of aged-appearance and age-related metabolic disorders. Symptoms of premature aging usually first develop in the second-third decades of life. We report a 27-year-old female who was admitted to our clinic at the age of eighteen with hyperglycemia. She was diagnosed with diabetes and type 4 dyslipidemia at the age of seven. In her family history, her parents were first cousins and she had three healthy brothers. On her first physical examination; she had bird-like face appearance, global hair loss, beaked nose, short stature and she was overweight. She had global hair loss with gray and thin hair. Hoarseness of voice and hyperkeratosis of skin were observed. She had bilateral cataracts and moderate sensorineural hearing loss. On psychiatric examination, borderline mental retardation was detected. She had severe insulin resistance and hypertriglyceridemia despite levothyroxine, gemfibrozil, omega-3 and intensive insulin treatment. Routine lipid apheresis was performed to lower the triglyceride levels reaching 5256 mg/dL. She also had focal segmental glomerulosclerosis, hepatosteatosis, osteoporosis and epilepsy. Disease was accompanied by several congenital deformities, such as Rathke’s cleft cyst, angiomyolipoma and femoral neck hypoplasia. WS is a rare genetic disorder characterized by multiple endocrine manifestations as well as soft tissue changes. We present a case of early disturbances that were diagnosed before typical clinical signs and symptoms. We propose that WS should be kept in mind when type 2 diabetes and hyperlipidemia are diagnosed early in childhood. Turk Jem 2015; 19: 99-104

  18. Objective and Subjective Voice Examination in Korean Medicine

    Directory of Open Access Journals (Sweden)

    Junsang Yu

    2014-09-01

    Full Text Available Objectives: When a person speaks, voice problems usually include pain or discomfort and/or difficulties in terms of the pitch, the loudness and the quality of the voice. When patients with voice problems induced by stroke, Parkinson’s disease, and systemic diseases involving the voice are examined, generally, of the Four Diagnoses (四診, a Diagnosis of Hearing can be used in current Korean medicine. The effects of acupuncture and herb medicine on voice problems have been reported for over 20 years. However, when it comes to improvements, objective and subjective evaluation methods need to be explained. Methods: Subjective methods for evaluating voice were studied through a literature search of old medicinal books containing Korean medicine diagnostics, and an objective evaluation method using Praat software is presented. Results: Korean medicine doctors analyze the patient’s voice in clinical settings unconsciously on a daily basis. However, most voice diagnoses depend on the doctor’s subjective evaluation. Voice qualities can be evaluated by using the Eight Principles (八綱, including Yin-Yang; the Five Elements (Phases; the Grade, Roughness, Breathy, Asthenic, Strained (GRBAS score, and the Visual Analogue Scale (VAS as subjective methods, and an acoustic analysis using the Praat program can be used as an objective method. Conclusion: A more complete voice examination can be achieved by using subjective and objective methods at the same time. For an objective explanation and management of patient’s voice problems or systemic disorders, an objective method should be used in Korean medicine, which already has many subjective diagnostic methods. More research needs to be conducted, and more clinical evidence needs to be collected in the future.

  19. Sustainable Consumer Voices

    DEFF Research Database (Denmark)

    Klitmøller, Anders; Rask, Morten; Jensen, Nevena

    2011-01-01

    Aiming to explore how user driven innovation can inform high level design strategies, an in-depth empirical study was carried out, based on data from 50 observations of private vehicle users. This paper reports the resulting 5 consumer voices: Technology Enthusiast, Environmentalist, Design Lover......, Pragmatist and Status Seeker. Expedient use of the voices in creating design strategies is discussed, thus contributing directly to the practice of high level design managers. The main academic contribution of this paper is demonstrating how applied anthropology can be used to generate insights...... into disruptive emergence of product service systems, where quantitative user analyses rely on historical continuation....

  20. EXPERIMENTAL STUDY OF FIRMWARE FOR INPUT AND EXTRACTION OF USER’S VOICE SIGNAL IN VOICE AUTHENTICATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    O. N. Faizulaieva

    2014-09-01

    Full Text Available Scientific task for improving the signal-to-noise ratio for user’s voice signal in computer systems and networks during the process of user’s voice authentication is considered. The object of study is the process of input and extraction of the voice signal of authentication system user in computer systems and networks. Methods and means for input and extraction of the voice signal on the background of external interference signals are investigated. Ways for quality improving of the user’s voice signal in systems of voice authentication are investigated experimentally. Firmware means for experimental unit of input and extraction of the user’s voice signal against external interference influence are considered. As modern computer means, including mobile, have two-channel audio card, two microphones are used in the voice signal input. The distance between sonic-wave sensors is 20 mm and it provides forming one direction pattern lobe of microphone array in a desired area of voice signal registration (from 100 Hz to 8 kHz. According to the results of experimental studies, the usage of directional properties of the proposed microphone array and space-time processing of the recorded signals with implementation of constant and adaptive weighting factors has made it possible to reduce considerably the influence of interference signals. The results of firmware experimental studies for input and extraction of the user’s voice signal against external interference influence are shown. The proposed solutions will give the possibility to improve the value of the signal/noise ratio of the useful signals recorded up to 20 dB under the influence of external interference signals in the frequency range from 4 to 8 kHz. The results may be useful to specialists working in the field of voice recognition and speaker discrimination.

  1. Eye movements reveal fast, voice-specific priming.

    Science.gov (United States)

    Papesh, Megan H; Goldinger, Stephen D; Hout, Michael C

    2016-03-01

    In spoken word perception, voice specificity effects are well-documented: When people hear repeated words in some task, performance is generally better when repeated items are presented in their originally heard voices, relative to changed voices. A key theoretical question about voice specificity effects concerns their time-course: Some studies suggest that episodic traces exert their influence late in lexical processing (the time-course hypothesis; McLennan & Luce, 2005), whereas others suggest that episodic traces influence immediate, online processing. We report 2 eye-tracking studies investigating the time-course of voice-specific priming within and across cognitive tasks. In Experiment 1, participants performed modified lexical decision or semantic classification to words spoken by 4 speakers. The tasks required participants to click a red "x" or a blue "+" located randomly within separate visual half-fields, necessitating trial-by-trial visual search with consistent half-field response mapping. After a break, participants completed a second block with new and repeated items, half spoken in changed voices. Voice effects were robust very early, appearing in saccade initiation times. Experiment 2 replicated this pattern while changing tasks across blocks, ruling out a response priming account. In the General Discussion, we address the time-course hypothesis, focusing on the challenge it presents for empirical disconfirmation, and highlighting the broad importance of indexical effects, beyond studies of priming.

  2. Secure digital voice communications in the Defense Data Network (DDN)

    Science.gov (United States)

    Bernet, M.; Gan, D.; Oesterreicher, C.

    1985-03-01

    This final report has investigated and validated one of the fourteen key features of the future, all-digital World-wide Digital Systems Architecture (WWDSA), namely the enhanced 2.4 Kbps secure voice survivability through the use of packetized voice and the use of packetized voice and the interconnection between the voice survivability through the use of packetized voice and the interconnection between the voice (DSN) phase implementation plan in the report, Secure Voice, as provided by the STU-IIs, can be implemented in the DDN in the late 1980s time-frame with no technical and minimum schedule risk. VIUs are proposed to interconnect, the family of secure voice terminals, called STU-IIs, to the DDN. VIUs contain modan, signalling and supervision (S/S), and processor modules and are supported by the implementation model of the protocol architecture that (with the TAC as processor module) was proposed in the report. An optimum system-level architecture employing the VIUs and the proposed in the implementation plan based on an extensive evaluation.

  3. Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system

    DEFF Research Database (Denmark)

    Castellano, Juan M; Bentsen, Agnete H; Sánchez-Garrido, Miguel A

    2011-01-01

    the timing of puberty; however, the potential underlying mechanisms remain poorly defined. Here we report how changes in the pattern of postnatal feeding affect the onset of puberty and evaluate key hormonal and neuropeptide [Kiss1/kisspeptin (Kp)] alterations linked to these early nutritional manipulations...... of puberty, together with higher levels of leptin and hypothalamic Kiss1 mRNA. Conversely, postnatal underfeeding caused a persistent reduction in body weight, lower ovarian and uterus weights, and delayed vaginal opening, changes that were paralleled by a decrease in leptin and Kiss1 mRNA levels. Kisspeptin...... at puberty were similar in all groups, except for enhanced responsiveness to low doses of Kp-10 in postnatally underfed rats. In conclusion, our data document that the timing of puberty is sensitive to both overfeeding and subnutrition during early (postnatal) periods and suggest that alterations...

  4. Effect of Instruction in Appropriate Rubato Usage on the Onset Timings of Musicians in Performances of Bach.

    Science.gov (United States)

    Johnson, Christopher M.

    2000-01-01

    Examines the effect of instruction in the use of specific rhythmic nuances on the timings of a musical performance. Forty volunteer upper-division and graduate students performed Johann Sebastian Bach's Suite no. 3 for Violoncello solo, Bouree no. 1, using a computer software program. Discusses the results. (CMK)

  5. Effect of Instruction in Appropriate Rubato Usage on the Onset Timings of Musicians in Performances of Bach.

    Science.gov (United States)

    Johnson, Christopher M.

    2000-01-01

    Examines the effect of instruction in the use of specific rhythmic nuances on the timings of a musical performance. Forty volunteer upper-division and graduate students performed Johann Sebastian Bach's Suite no. 3 for Violoncello solo, Bouree no. 1, using a computer software program. Discusses the results. (CMK)

  6. Sustainable Consumer Voices

    DEFF Research Database (Denmark)

    Klitmøller, Anders; Rask, Morten; Jensen, Nevena

    2011-01-01

    Aiming to explore how user driven innovation can inform high level design strategies, an in-depth empirical study was carried out, based on data from 50 observations of private vehicle users. This paper reports the resulting 5 consumer voices: Technology Enthusiast, Environmentalist, Design Lover...

  7. Voices of courage

    Directory of Open Access Journals (Sweden)

    Noraida Abdullah Karim

    2007-07-01

    Full Text Available In May 2007 the Women’s Commission for Refugee Women and Children1 presented its annual Voices of Courage awards to three displaced people who have dedicated their lives to promoting economic opportunities for refugee and displaced women and youth. These are their (edited testimonies.

  8. Listen to a voice

    DEFF Research Database (Denmark)

    Hølge-Hazelton, Bibi

    2001-01-01

    Listen to the voice of a young girl Lonnie, who was diagnosed with Type 1 diabetes at 16. Imagine that she is deeply involved in the social security system. She lives with her mother and two siblings in a working class part of a small town. She is at a special school for problematic youth, and he...

  9. Political animal voices

    NARCIS (Netherlands)

    Meijer, E.R.

    2017-01-01

    In this thesis, I develop a theory of political animal voices. The first part of the thesis focuses on non-human animal languages and forming interspecies worlds. I first investigate the relation between viewing language as exclusively human and seeing humans as categorically different from other

  10. the Voice of Tomorrow

    Institute of Scientific and Technical Information of China (English)

    AlanBurdick

    2003-01-01

    Have you heard Mide? Coule be.Mike is a professional reader,and he's everywhere these days. On MapQuest, the Web-based map service,he'll read aloud whatever directions you ask for. If you like to have AOL or Yahoo! e-mail read aloud to you over the phone, that's Mike's voice you 're hearing. Soon

  11. What the voice reveals.

    NARCIS (Netherlands)

    Ko, Sei Jin

    2007-01-01

    Given that the voice is our main form of communication, we know surprisingly little about how it impacts judgment and behavior. Furthermore, the modern advancement in telecommunication systems, such as cellular phones, has meant that a large proportion of our everyday interactions are conducted voca

  12. The Inner Voice

    Science.gov (United States)

    Ridgway, Anthony James

    2009-01-01

    The inner voice- we all know what it is because we all have it and use it when we are thinking or reading, for example. Little work has been done on it in our field, with the notable exception of Brian Tomlinson, but presumably it must be a cognitive phenomenon which is of great importance in thinking, language learning, and reading in a foreign…

  13. Moving beyond Youth Voice

    Science.gov (United States)

    Serido, Joyce; Borden, Lynne M.; Perkins, Daniel F.

    2011-01-01

    This study combines research documenting the benefits of positive relationships between youth and caring adults on a young person's positive development with studies on youth voice to examine the mechanisms through which participation in youth programs contributes to positive developmental outcomes. Specifically, the study explores whether youth's…

  14. Bodies and Voices

    DEFF Research Database (Denmark)

    A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation to the imprisoned, dismembered, remembered...

  15. Voices for Careers.

    Science.gov (United States)

    York, Edwin G.; Kapadia, Madhu

    Listed in this annotated bibliography are 502 cassette tapes of value to career exploration for Grade 7 through the adult level, whether as individualized instruction, small group study, or total class activity. Available to New Jersey educators at no charge, this Voices for Careers System is also available for duplication on request from the New…

  16. What the voice reveals

    NARCIS (Netherlands)

    Ko, Sei Jin

    2007-01-01

    Given that the voice is our main form of communication, we know surprisingly little about how it impacts judgment and behavior. Furthermore, the modern advancement in telecommunication systems, such as cellular phones, has meant that a large proportion of our everyday interactions are conducted voca

  17. Bodies and Voices

    DEFF Research Database (Denmark)

    A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation to the imprisoned, dismembered, remembered...

  18. Ice nucleation properties of mineral dust particles: determination of onset RHi, IN active fraction, nucleation time-lag, and the effect of active sites on contact angles

    Directory of Open Access Journals (Sweden)

    S. Dobbie

    2010-01-01

    Full Text Available A newly developed ice nucleation experimental set up was used to investigate the heterogeneous ice nucleation properties of three Saharan and one Spanish dust particle samples. It was observed that the spread in the onset relative humidities with respect to ice (RHi for Saharan dust particles varied from 104% to 110%, whereas for the Spanish dust from 106% to 110%. The elemental composition analysis shows a prominent Ca feature in the Spanish dust sample which could potentially explain the differences in nucleation threshold. Although the spread in the onset RHi for the three Saharan dust samples were in agreement, the active fractions and nucleation time-lags calculated at various temperature and RHi conditions were found to differ. This could be due to the subtle variation in the elemental composition of the dust samples, and surface irregularities like steps, cracks, cavities etc. A combination of classical nucleation theory and active site theory is used to understand the importance of these surface irregularities on the nucleability parameter, contact angle that is widely used in ice cloud modeling. These calculations show that the surface irregularities can reduce the contact angle by approximately 10 degrees.

  19. Realisation of voicing by French-speaking CI children after long-term implant use: An acoustic study.

    Science.gov (United States)

    Grandon, Bénédicte; Vilain, Anne; Lœvenbruck, Hélène; Schmerber, Sébastien; Truy, Eric

    2017-01-01

    Studies of speech production in French-speaking cochlear-implanted (CI) children are very scarce. Yet, difficulties in speech production have been shown to impact the intelligibility of these children. The goal of this study is to understand the effect of long-term use of cochlear implant on speech production, and more precisely on the coordination of laryngeal-oral gestures in stop production. The participants were all monolingual French children: 13 6;6- to 10;7-year-old CI children and 20 age-matched normally hearing (NH) children. We compared /p/, /t/, /k/, /b/, /d/ and /g/ in word-initial consonant-vowel sequences, produced in isolation in two different tasks, and we studied the effects of CI use, vowel context, task and age factors (i.e. chronological age, age at implantation and duration of implant use). Statistical analyses show a difference in voicing production between groups for voiceless consonants (shorter Voice Onset Times for CI children), with significance reached only for /k/, but no difference for voiced consonants. Our study indicates that in the long run, use of CI seems to have limited effects on the acquisition of oro-laryngeal coordination needed to produce voicing, except for specific difficulties located on velars. In a follow-up study, further acoustic analyses on vowel and fricative production by the same children reveal more difficulties, which suggest that cochlear implantation impacts frequency-based features (second formant of vowels and spectral moments of fricatives) more than durational cues (voicing).

  20. Rearranged anaplastic lymphoma kinase (ALK) gene found for the first time in adult-onset papillary thyroid cancer cases among atomic bomb survivors

    Energy Technology Data Exchange (ETDEWEB)

    Hamatani, K.; Mukai, M.; Takahashi, K.; Nakachi, K.; Kusunoki, Y. [Radiobiology/Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima (Japan); Hayashi, Y. [Geriatric Health Service Facility Hidamari, Hiroshima (Japan)

    2012-07-01

    Full text of the publication follows: Thyroid cancer is one of the malignancies most strongly associated with ionizing radiation in humans. Epidemiology studies of atomic bomb (A-bomb) survivors have indicated that excess relative risk of papillary thyroid cancer per Gy was remarkably high in the survivors. We therefore aim to clarify mechanisms linking A-bomb radiation exposure and development of papillary thyroid cancer. Toward this end, we intend to clarify characteristics of gene alterations occurring in radiation-associated adult-onset papillary thyroid cancer from the Life Span Study cohort of A-bomb survivors. We have thus far found that with increased radiation dose, papillary thyroid cancer cases with chromosomal rearrangements (mainly RET/PTC rearrangements) significantly increased and papillary thyroid cancer cases with point mutations (mainly BRAF-V600E) significantly decreased. Papillary thyroid cancer cases with non-detected gene alterations that carried no mutations in RET, NTRK1, BRAF or RAS genes tended to increase with increased radiation dose. In addition, we found that relative frequency of these papillary thyroid cancer cases significantly decreased with time elapsed since exposure. Through analysis of papillary thyroid cancer cases with non-detected gene alterations, we recently discovered a new type of rearrangement for the first time in papillary thyroid cancer, i.e., rearranged anaplastic lymphoma kinase (ALK) gene, although identification of any partner gene(s) is needed. Specifically, rearrangement of ALK was found in 10 of 19 exposed papillary thyroid cancer cases with non-detected gene alterations but not in any of the six non-exposed papillary thyroid cancer cases. Furthermore, papillary thyroid cancer with ALK rearrangement was frequently found in the cases with high radiation dose or with short time elapsed since A-bomb exposure. These results suggest that chromosomal rearrangement, typically of RET and ALK, may play an important

  1. Nursing support at the onset of rheumatoid arthritis: Time and space for emotions, practicalities and self-management.

    Science.gov (United States)

    Hehir, M; Carr, M; Davis, B; Radford, S; Robertson, L; Tipler, S; Hewlett, S

    2008-06-01

    Following a diagnosis of rheumatoid arthritis (RA), patients have to adapt to lifelong, unpredictable but repeated episodes of pain and disability, potentially leading to permanent loss of function and its consequences on their lives. We established nurse clinics with the aim of supporting newly diagnosed RA patients in adapting to and managing their long-term condition. The aim of this study was to explore the content of clinic discussions in this new clinical service, in order to ascertain patients' needs upon diagnosis. All clinic letters from the nurse to the family doctor were analysed. Every topic mentioned was systematically coded independently by a researcher and a patient research partner, who compared and agreed codes. Codes were organized into categories, and, finally, into overarching themes. Twenty-four patients had 74 appointment letters. A total of 79 codes were identified, from which ten categories emerged, and, finally, three overarching themes. The first theme related to 'Emotional support', which underpinned the other two themes and was discussed in almost all appointments. Issues included discussions about the emotional consequences of RA, needing time to adjust, frustration and fears for the future. The second theme 'Practicalities of the treatment of RA', included subordinate themes relating to the nature of RA, such as identity, cause, timeline, consequences and treatment. Medication issues were discussed and referrals to the multidisciplinary team were made. The final theme related to the 'Self-management of RA', and included discussions on physical symptoms and their management. The offer to attend a nurse clinic soon after diagnosis allowed RA patients to discuss a wide range of practical and self-management issues. However, most patients also took the opportunity and time to discuss emotional reactions and adaptations to diagnosis. The data suggest an unmet need for emotional support that a nurse clinic might be able to provide.

  2. April 16th : The World Voice Day

    NARCIS (Netherlands)

    Svec, Jan G.; Behlau, Mara

    2007-01-01

    Although the voice is used as an everyday basis of speech, most people realize its importance only when a voice problem arises. Increasing public awareness of the importance of the voice and alertness to voice problems are the main goals of the World Voice Day, which is celebrated yearly on April 16

  3. Risk factors for voice problems in teachers

    NARCIS (Netherlands)

    Kooijman, P. G. C.; de Jong, F. I. C. R. S.; Thomas, G.; Huinck, W.; Donders, R.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  4. You're a What? Voice Actor

    Science.gov (United States)

    Liming, Drew

    2009-01-01

    This article talks about voice actors and features Tony Oliver, a professional voice actor. Voice actors help to bring one's favorite cartoon and video game characters to life. They also do voice-overs for radio and television commercials and movie trailers. These actors use the sound of their voice to sell a character's emotions--or an advertised…

  5. Risk factors for voice problems in teachers

    NARCIS (Netherlands)

    Kooijman, P. G. C.; de Jong, F. I. C. R. S.; Thomas, G.; Huinck, W.; Donders, R.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  6. Risk factors for voice problems in teachers.

    NARCIS (Netherlands)

    Kooijman, P.G.C.; Jong, F.I.C.R.S. de; Thomas, G.; Huinck, W.J.; Donders, A.R.T.; Graamans, K.; Schutte, H.K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  7. Reducing the time-lag between onset of chest pain and seeking professional medical help: a theory-based review

    Directory of Open Access Journals (Sweden)

    Baxter Susan K

    2013-02-01

    Full Text Available Abstract Background Research suggests that there are a number of factors which can be associated with delay in a patient seeking professional help following chest pain, including demographic and social factors. These factors may have an adverse impact on the efficacy of interventions which to date have had limited success in improving patient action times. Theory-based methods of review are becoming increasingly recognised as important additions to conventional systematic review methods. They can be useful to gain additional insights into the characteristics of effective interventions by uncovering complex underlying mechanisms. Methods This paper describes the further analysis of research papers identified in a conventional systematic review of published evidence. The aim of this work was to investigate the theoretical frameworks underpinning studies exploring the issue of why people having a heart attack delay seeking professional medical help. The study used standard review methods to identify papers meeting the inclusion criterion, and carried out a synthesis of data relating to theoretical underpinnings. Results Thirty six papers from the 53 in the original systematic review referred to a particular theoretical perspective, or contained data which related to theoretical assumptions. The most frequently mentioned theory was the self-regulatory model of illness behaviour. Papers reported the potential significance of aspects of this model including different coping mechanisms, strategies of denial and varying models of treatment seeking. Studies also drew attention to the potential role of belief systems, applied elements of attachment theory, and referred to models of maintaining integrity, ways of knowing, and the influence of gender. Conclusions The review highlights the need to examine an individual’s subjective experience of and response to health threats, and confirms the gap between knowledge and changed behaviour. Interventions face

  8. Enamel defect of primary dentition in SGA children in relation to onset time of intrauterine growth disturbance

    Directory of Open Access Journals (Sweden)

    Willyanti Soewondo Sjarif

    2013-06-01

    Full Text Available Background: Prenatal disturbances disturb the development of organs resulting in small for gestational age (SGA babies and also causes enamel defects in primary teeth. There are disturbances occur in the beginning of pregnancy causing symmetrical SGA, and asymmetrical type of SGA, where the disturbances occur late in pregnancy. Purpose: This research was to determined differences in severity of enamel defect of primary dentition in small for gestational age children based on the time of intrauterine growth restriction. Methods: This was a clinical epidemiological cohort study. The Ponderal index was used to determine SGA type. The subjects were 129 SGA children aged 9-42 months, 82 with asymmetrical SGA and 47 with symmetrical SGA. Two hundred normal birth weight children were the control group. Intra-oral examinations to determine enamel defect used the FDI modification of the Developmental Defect of Enamel score at 3 months intervals. Statistical t-tests were used to test the difference in severity of enamel defect, and chisquare to find out the difference of Relative Risk Ratio (RRR. Results: The results showed that the enamel defect scores of symmetrical SGA were significantly higher than those with asymmetrical SGA. RRR for severe defect was also significantly higher in symmetrical type for anterior and canines. Conclusion: The study suggested that the severity of enamel defect for infants with symmetrical SGA was higher than those with asymmetrical SGA, indicating that the severity of the defect occurs in the beginning of pregnancy is more severe than in the late pregnancy.Latar belakang: Adanya gangguan prenatal mengganggu perkembangan organ, mengakibatkan terjadinya bayi lahir dengan kecil masa kehamilan (KMK dan defek email pada gigi sulung. Terdapat 2 tipe KMK yaitu tipe simetri; gangguan terjadi pada awal kehamilan; dimana lingkar kepala, berat dan panjang lahir lebih rendah dari normal. Tipe asimetri dimana gangguan terjadi saat

  9. Speaker comfort and increase of voice level in lecture rooms

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Gade, Anders Christian; Bellester, G P

    2008-01-01

    the objectively measurable parameters of the rooms and the objective voice power produced by speakers. In rooms with different sizes, reverberation time and other physical attributes, the sound power levels produced by six speakers where measured while giving a short lecture. Relevant room acoustic parameters......Teachers often suffer health problems or tension related to their voice. These problems may be related to there working environment, including room acoustics of the lecture rooms which forces them to stress their voices. The present paper describes a first effort in finding relationships between...

  10. A TDM link with channel coding and digital voice.

    Science.gov (United States)

    Jones, M. W.; Tu, K.; Harton, P. L.

    1972-01-01

    The features of a TDM (time-division multiplexed) link model are described. A PCM telemetry sequence was coded for error correction and multiplexed with a digitized voice channel. An all-digital implementation of a variable-slope delta modulation algorithm was used to digitize the voice channel. The results of extensive testing are reported. The measured coding gain and the system performance over a Gaussian channel are compared with theoretical predictions and computer simulations. Word intelligibility scores are reported as a measure of voice channel performance.

  11. Keyboard With Voice Output

    Science.gov (United States)

    Huber, W. C.

    1986-01-01

    Voice synthesizer tells what key is about to be depressed. Verbal feedback useful for blind operators or where dim light prevents sighted operator from seeing keyboard. Also used where operator is busy observing other things while keying data into control system. Used as training aid for touch typing, and to train blind operators to use both standard and braille keyboards. Concept adapted to such equipment as typewriters, computers, calculators, telephones, cash registers, and on/off controls.

  12. Predicting the risk for hospital-onset Clostridium difficile infection (HO-CDI) at the time of inpatient admission: HO-CDI risk score.

    Science.gov (United States)

    Tabak, Ying P; Johannes, Richard S; Sun, Xiaowu; Nunez, Carlos M; McDonald, L Clifford

    2015-06-01

    To predict the likelihood of hospital-onset Clostridium difficile infection (HO-CDI) based on patient clinical presentations at admission Retrospective data analysis Six US acute care hospitals Adult inpatients We used clinical data collected at the time of admission in electronic health record (EHR) systems to develop and validate a HO-CDI predictive model. The outcome measure was HO-CDI cases identified by a nonduplicate positive C. difficile toxin assay result with stool specimens collected >48 hours after inpatient admission. We fit a logistic regression model to predict the risk of HO-CDI. We validated the model using 1,000 bootstrap simulations. Among 78,080 adult admissions, 323 HO-CDI cases were identified (ie, a rate of 4.1 per 1,000 admissions). The logistic regression model yielded 14 independent predictors, including hospital community onset CDI pressure, patient age ≥65, previous healthcare exposures, CDI in previous admission, admission to the intensive care unit, albumin ≤3 g/dL, creatinine >2.0 mg/dL, bands >32%, platelets ≤150 or >420 109/L, and white blood cell count >11,000 mm3. The model had a c-statistic of 0.78 (95% confidence interval [CI], 0.76-0.81) with good calibration. Among 79% of patients with risk scores of 0-7, 19 HO-CDIs occurred per 10,000 admissions; for patients with risk scores >20, 623 HO-CDIs occurred per 10,000 admissions (Prisk identification tool for HO-CDI preventive interventions and outcome comparisons.

  13. Why Is My Voice Changing? (For Teens)

    Science.gov (United States)

    ... Week of Healthy Breakfasts Shyness Why Is My Voice Changing? KidsHealth > For Teens > Why Is My Voice ... deeper than a girl's, though. What Causes My Voice to Change? At puberty, guys' bodies begin producing ...

  14. Common Problems That Can Affect Your Voice

    Science.gov (United States)

    ... near you Common Problems That Can Affect Your Voice Common Problems That Can Affect Your Voice Patient ... that traditionally accompany gastro esophageal reflux disease (GERD). Voice Misuse and Overuse Speaking is a physical task ...

  15. Auditory verbal hallucinations and continuum models of psychosis: A systematic review of the healthy voice-hearer literature.

    Science.gov (United States)

    Baumeister, David; Sedgwick, Ottilie; Howes, Oliver; Peters, Emmanuelle

    2017-02-01

    Recent decades have seen a surge of research interest in the phenomenon of healthy individuals who experience auditory verbal hallucinations, yet do not exhibit distress or need for care. The aims of the present systematic review are to provide a comprehensive overview of this research and examine how healthy voice-hearers may best be conceptualised in relation to the diagnostic versus 'quasi-' and 'fully-dimensional' continuum models of psychosis. A systematic literature search was conducted, resulting in a total of 398 article titles and abstracts that were scrutinised for appropriateness to the present objective. Seventy articles were identified for full-text analysis, of which 36 met criteria for inclusion. Subjective perceptual experience of voices, such as loudness or location (i.e., inside/outside head), is similar in clinical and non-clinical groups, although clinical voice-hearers have more frequent voices, more negative voice content, and an older age of onset. Groups differ significantly in beliefs about voices, control over voices, voice-related distress, and affective difficulties. Cognitive biases, reduced global functioning, and psychiatric symptoms such as delusions, appear more prevalent in healthy voice-hearers than in healthy controls, yet less than in clinical samples. Transition to mental health difficulties is increased in HVHs, yet only occurs in a minority and is predicted by previous mood problems and voice distress. Whilst healthy voice-hearers show similar brain activity during hallucinatory experiences to clinical voice-hearers, other neuroimaging measures, such as mismatch negativity, have been inconclusive. Risk factors such as familial and childhood trauma appear similar between clinical and non-clinical voice-hearers. Overall the results of the present systematic review support a continuum view rather than a diagnostic model, but cannot distinguish between 'quasi' and 'fully' dimensional models. Healthy voice-hearers may be a key

  16. Voice over IP in Wireless Heterogeneous Networks

    DEFF Research Database (Denmark)

    Fathi, Hanane; Chakraborty, Shyam; Prasad, Ramjee

    The convergence of different types of traffic has preceded the convergence of systems and services in a wireless heterogeneous network. Voice and data traffic are usually treated separate in both 2G and 2.5G wireless networks. With advances in packet switching technology and especially with the d...... and to the discruption caused by the user mobility during the session. Voice over IP in Wireless Hetetrogeneous Networks thus investigates and proposes cross-layer techniques for realizing time-efficient control mechanisms for VoIP: signaling, mobility and security.......The convergence of different types of traffic has preceded the convergence of systems and services in a wireless heterogeneous network. Voice and data traffic are usually treated separate in both 2G and 2.5G wireless networks. With advances in packet switching technology and especially....... The focus of Voice over IP in Wierless Heterogeneous Networks is on mechanisms that affect the VoIP user satisfaction  while not explicitly involved in the media session. This relates to the extra delays introduced by the security and the signaling protocols used to set up an authorized VoIP session...

  17. Voice recognition software for clinical use.

    Science.gov (United States)

    Korn, K

    1998-11-01

    The current generation voice recognition products truly offer the promise of voice recognition systems, that are financially and operationally acceptable for use in a health care facility. Although the initial capital outlay for the purchase of such equipment may be substantial, the long-term benefit is felt to outweigh the expense. The ability to utilize computer equipment for educational purposes and information management alone helps to rationalize the cost. In addition, it is important to remember that the Internet has become a substantial source of information which provides another functional use for this equipment. Although one can readily see the implication for such a program in clinical practice, other uses for the program should not be overlooked. Uses far beyond the writing of clinic notes and correspondence can be easily envisioned. Utilization of voice recognition software offers clinical practices the ability to produce quality printed records in a timely and cost-effective manner. After learning procedures for the selected product and appropriately formatting word processing software and printers, printed progress notes should be able to be produced in less time than traditional dictation and transcription methods. Although certain procedures and practices may need to be altered, or may preclude optimal utilization of this type of system, many advantages are apparent. It is recommended that facilities consider utilization of Voice Recognition products such as Dragon Systems Naturally Speaking Software, or at least consider a trial of this method with one of the limited-feature products, if current dictation practices are unsatisfactory or excessively costly. Free downloadable trial software or single user software can provide a reduced-cost method for trial evaluation of such products if a major commitment is not felt to be desired. A list of voice recognition software manufacturer web sites may be accessed through the following: http

  18. VOICE REHABILITATION FOLLOWING TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thiagarajan

    2015-03-01

    Full Text Available Despite continuing advances in surgical management of laryngeal malignancy, total laryngectomy is still the treatment of choice in advanced laryngeal malignancies. Considering the longevity of the patient following total laryngectomy, various measures have been adopted in order to provide voice function to the patient. Significant advancements have taken place in voice rehabilitation of post laryngectomy patients. Advancements in oncological surgical techniques and irradiation techniques have literally cured laryngeal malignancies. Among the various voice rehabilitation techniques available TEP (Tracheo oesophageal puncture is considered to be the gold standard. This article attempts to explore the various voice rehabilitation technique available with primary focus on TEP.

  19. Effect of Voicing on Spacial Indices of Consonants

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Keyhani

    2009-12-01

    Full Text Available Background and Aim: For better using of electropalatography in assessment and treatment procedures it is important to know normal tongue to palate contact patterns. Several factors can change consonant’s articulatory patterns. One of them is voicing. In addition to determine amount of spacial indices of studied consonants, this research aimed to study tongue behavior related to change in voicing. Materials and Methods: This is a descriptive analytic study. Consonant linguapalatal contacts were studied using reading electropalatography by recording 4 normal Persian speaking adults (aged between 21-25 repeating CVCV syllables (C=/s,z,t,d/, V=/a/ ten times. Contact patterns were examined for total number of electrodes contacted and other spatial indices. Comparisons were made across voicing contrast.Results: In this study amount of spacial indices of studied consonants determined. It’s found that there was not significant difference between voiced and voiceless cognate according to number of contact and other special indices.Conclusion: The findings of this study are in according with previous studies in other languages about the effect of voicing upon linguapalatal contact patterns. Difference in voicing does not make clear change in spacial indices related to tongue contact pattern. Compared to other parts, Tip of the tongue seem to be more sensitive for change in voicing and oral air pressure.

  20. Effect of testosterone therapy on the female voice

    Science.gov (United States)

    Glaser, R.; York, A.; Dimitrakakis, C.

    2016-01-01

    Abstract Objectives This prospective study was designed to investigate the effect of testosterone, delivered by subcutaneous implants, on the female voice. Methods Ten women who had opted for testosterone therapy were recruited for voice analysis. Voices were recorded prior to treatment and at 3 months, 6 months, and 12 months while on testosterone therapy. Acoustic samples were collected with subjects reading a sentence, reading a paragraph, and participating in a conversation. Significant changes in the voice over time were investigated using a repeated-measures analysis of variance with the fundamental frequency (F 0) as a response variable. Demographic variables associated with characteristics of the voice were assessed. Results There were no significant differences in average F 0 related to smoking history, menopausal status, weight, or body mass index. There was no difference in average fundamental speaking frequency (sentence, paragraph, conversation) between the pre-treatment group and any post-treatment group at 3 and 12 months. There was an increase in sentence speech F 0 at 6 months. Two of three patients with lower than expected F 0 at baseline improved on testosterone therapy. Conclusion Therapeutic levels of testosterone, delivered by subcutaneous implant, had no adverse affect on the female voice including lowering or deepening of the voice. PMID:26857354

  1. The impact of voice on speech realization

    OpenAIRE

    Jelka Breznik

    2014-01-01

    The study discusses spoken literary language and the impact of voice on speech realization. The voice consists of a sound made by a human being using the vocal folds for talking, singing, laughing, crying, screaming… The human voice is specifically the part of human sound production in which the vocal folds (vocal cords) are the primary sound source. Our voice is our instrument and identity card. How does the voice (voice tone) affect others and how do they respond, positively or negatively? ...

  2. Mobile Phones and Voice-Based Educational Services in Rural India: Project RuralVoice

    OpenAIRE

    Ruohonen, Mikko; Turunen, Markku; Mahajan, Gururaj; Linna, Juhani; Kumar, Vivek; Das, Himadri

    2012-01-01

    Part 1: Mobile Learning; International audience; Voice-based services offer major business opportunities in developing areas such as India and Africa. In these areas mobile phones have become very popular, and their usage is increasing all the time. In this project, we study the deployment of voice-based mobile educational services for developing countries. Our study is based on a Spoken Web technology developed by IBM Research Labs, and our focus is on India’s Bottom of the Pyramid (BoP). It...

  3. Regularly scheduled, day-time, slow-onset 60 Hz electric and magnetic field exposure does not depress serum melatonin concentration in nonhuman primates

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, W.R.; Smith, H.D.; Orr, J.L. [Southwest Research Inst., San Antonio, TX (United States); Reiter, R.J.; Barlow-Walden, L. [Univ. of Texas Health Science Center, San Antonio, TX (United States)

    1995-12-31

    Experiments conducted with laboratory rodents indicate that exposure to 60 Hz electric fields or magnetic fields can suppress nocturnal melatonin concentrations in pineal gland and blood. In three experiments employing three field-exposed and three sham-exposed nonhuman primates, each implanted with an indwelling venous cannula to allow repeated blood sampling, the authors studied the effects of either 6 kV/m and 50 {micro}T (0.5 G) or 30 kV/m and 100 {micro}T (1.0 G) on serum melatonin patterns. The fields were ramped on and off slowly, so that no transients occurred. Extensive quality control for the melatonin assay, computerized control and monitoring of field intensities, and consistent exposure protocols were used. No changes in nocturnal serum melatonin concentration resulted from 6 weeks of day-time exposure with slow field onset/offset and a highly regular exposure protocol. These results indicate that, under the conditions tested, day-time exposure to 60 Hz electric and magnetic fields in combination does not result in melatonin suppression in primates.

  4. Long-short GRBs within the horizon of the advanced LIGO/VIRGO network and Time lag between compact object coalescence and GRB onset

    CERN Document Server

    Li, Xiang; Fan, Yi-Zhong; Wei, Da-Ming

    2016-01-01

    Short duration GRBs (SGRBs) are widely believed to be powered by the mergers of compact binaries, like binary neutron stars or possibly neutron star-black hole binaries. Though the prospect of detecting SGRBs with gravitational wave (GW) signals by the advanced LIGO/VIRGO network is promising, no known SGRB has been found within the expected advanced LIGO/VIRGO sensitivity range. We argue, however, that the two long-short GRBs (GRB 060505 and GRB 060614) may be within the horizon of advanced GW detectors. In the upcoming era of GW astronomy, the merger origin of some long-short GRBs, as favored by the macronova signature displayed in GRB 060614, can be unambiguously tested. The model-dependent time-lags between the merger and the onset of the prompt emission of GRB are estimated. The comparison of such time-lags between model prediction to the real data expected in the era of the GW astronomy would be helpful in revealing the physical processes taking place at the central engine (including the launch of the r...

  5. The association of a preschool voice education program with changes in yelling frequency.

    Science.gov (United States)

    Marcus, Lauren; Kiernan, Barbara; Barkmeier-Kraemer, Julie M

    2013-05-01

    Voice problems in children can occur as early as infancy. Early onset of voice problems can carry social and academic penalties, and negatively affect voice in adolescence or adulthood. Unfortunately, only 1% of school-aged children receive voice therapy despite a 6 to 24% prevalence of voice disorders in school-aged children. One alternative may be to use a classroom-based voice education curriculum to effectively reduce yelling frequency, the most common behavior associated with phonotrauma-related voice problems in children. A classroom-based voice education curriculum was administered to preschool children by the preschool speech-language pathologists in a university-affiliated program. Classroom teachers provided cueing and reinforcement of curriculum strategies for 8 weeks following the program. Baseline frequencies of participant yelling behaviors were compared with postprogram frequencies. Results demonstrated significant reduction in yelling frequencies from pre- to postprogram, particularly in those judged as high-frequency yellers prior to the program. Important factors for future consideration are discussed.

  6. Graduate student voice use and vocal efficiency in an opera rehearsal week: a case study.

    Science.gov (United States)

    Schloneger, Matthew J

    2011-11-01

    The purpose of this case study was to document graduate voice students' (N=2) voice use before, during, and after an intense week of opera rehearsals through (1) acquired Ambulatory Phonation Monitor (APM) data, (2) daily surveys, (3) participant activity logs, (4) three administrations of the Singing Voice Handicap Index (SVHI), and (5) pre- and post-stroboscopic laryngeal examinations. Two female graduate students, both of whom were cast in a university production of Stravinsky's The Rake's Progress (stage names Anne and Baba) and both of whom served as graduate teaching assistants in voice, wore APMs during waking hours for 9 days, including two pretest baseline days, a 5-day intensive rehearsal week just before the opera production week, and 2 baseline days after opera performances were completed. Mean phonation time dose percentages (Dt) and daily distance dose averages (Dd) were similar between the pre- and posttest periods and the intensive week. Disaggregation of acquired data by four types of activities (opera rehearsals, personal practice time, voice teaching time, and nonrehearsal or teaching time) indicated that the highest mean Dts and Dds were acquired during personal practice time and voice teaching time. Daily surveys and SVHI data as well as the pre- and post-stroboscopies indicated no notable changes occurring in vocal health. Results indicated that these singers were conscious about their voice use during periods of extensive performance demands. However, high vocal doses during voice teaching times suggest that these individuals might benefit from teacher voice care education.

  7. Superior voice timbre processing in musicians.

    Science.gov (United States)

    Chartrand, Jean-Pierre; Belin, Pascal

    2006-09-25

    After several years of exposure to musical instrument practice, musicians acquire a great expertise in processing auditory features like tonal pitch or timbre. Here we compared the performance of musicians and non-musicians in two timbre discrimination tasks: one using instrumental timbres, the other using voices. Both accuracy (d-prime) and reaction time measures were obtained. The results indicate that the musicians performed better than the non-musicians at both tasks. The musicians also took more time to respond at both tasks. One interpretation of this result is that the expertise musicians acquired with instrumental timbres during their training transferred to timbres of voice. The musician participants may also have used different cognitive strategies during the experiment. Higher response times found in musicians can be explained by a longer verbal-auditory memory and the use of a strategy to further process auditory features.

  8. The Voice Handicap Index with Post-Laryngectomy Male Voices

    Science.gov (United States)

    Evans, Eryl; Carding, Paul; Drinnan, Michael

    2009-01-01

    Background: Surgical treatment for advanced laryngeal cancer involves complete removal of the larynx ("laryngectomy") and initial total loss of voice. Post-laryngectomy rehabilitation involves implementation of different means of "voicing" for these patients wherever possible. There is little information about laryngectomees'…

  9. Pedagogic Voice: Student Voice in Teaching and Engagement Pedagogies

    Science.gov (United States)

    Baroutsis, Aspa; McGregor, Glenda; Mills, Martin

    2016-01-01

    In this paper, we are concerned with the notion of "pedagogic voice" as it relates to the presence of student "voice" in teaching, learning and curriculum matters at an alternative, or second chance, school in Australia. This school draws upon many of the principles of democratic schooling via its utilisation of student voice…

  10. Chronicity of Voice-Related Health Care Utilization in the General Medicine Community.

    Science.gov (United States)

    Cohen, Seth M; Lee, Hui-Jie; Roy, Nelson; Misono, Stephanie

    2017-04-01

    Objectives To examine voice-related health care utilization of patients in the general medical community without otolaryngology evaluation and explore factors associated with prolonged voice-related health care. Study Design Retrospective cohort analysis. Setting Large, national administrative US claims database. Subjects and Methods Patients with voice disorders per International Classification of Diseases, Ninth Revision, Clinical Modification ( ICD-9-CM) codes from January 1, 2010, to December 31, 2012, seen by a general medical physician, and who did not see an otolaryngologist in the subsequent year were included. Voice-related health care utilization, patient demographics, comorbid conditions, and index laryngeal diagnosis were collected. Logistic regression with variable selection was performed to evaluate the association between predictors and ≥30 days of voice-related health care use. Results In total, 46,205 unique voice-disordered patients met inclusion criteria. Of these patients, 8.5%, 10.0%, and 12.5% had voice-related health care use of ≥90, ≥60, and ≥30 days, respectively. Of the ≥30-day subset, 80.3% and 68.5%, respectively, had ≥60 and ≥90 days of voice-related health care utilization. The ≥30-day subset had more general medicine and nonotolaryngology specialty physician visits, more prescriptions and procedures, and 4 times the voice-related health care costs compared with those in the <30-day subset. Age, sex, employment status, initial voice disorder diagnosis, and comorbid conditions were related to ≥30 days of voice-related health care utilization. Conclusions Thirty days of nonotolaryngology-based care for a voice disorder may represent a threshold beyond which patients are more likely to experience prolonged voice-related health care utilization. Specific factors were associated with extended voice-related health care.

  11. Is Student Voice Necessarily Empowering? Problematising Student Voice as a Form of Higher Education Governance

    Science.gov (United States)

    Freeman, Rebecca

    2016-01-01

    Student voice, namely the institutionalisation of students' contributions to the evaluation, and increasingly, the day-to-day running of higher education, has a wide-ranging influence. It shapes the concerns of management and academics; it changes the organisation and content of degree courses and, at times, challenges authority. Through her…

  12. Is Student Voice Necessarily Empowering? Problematising Student Voice as a Form of Higher Education Governance

    Science.gov (United States)

    Freeman, Rebecca

    2016-01-01

    Student voice, namely the institutionalisation of students' contributions to the evaluation, and increasingly, the day-to-day running of higher education, has a wide-ranging influence. It shapes the concerns of management and academics; it changes the organisation and content of degree courses and, at times, challenges authority. Through her…

  13. Circadian Variation Of Stroke Onset

    Directory of Open Access Journals (Sweden)

    Kamath vasantha

    2003-01-01

    Full Text Available Diurnal variations in various physiological and biochemical functions and certain pathological events like myocardial infarction and stroke have been documented. We studied prospectively one hundred and seven patients of acute onset stroke confirmed by computed tomography for the exact time of onset, risk factors and type of stroke. Patients who were unclear of time of onset and with a diagnosis of cerebral venous thrombosis or sub-arachnoid hemorrhage were excluded. Infarction was detected in 71 patients and hemorrhage in 33 patients. Men out numbered women (1:6:1. Hypertension was more frequent in hemorrhage in the morning time (5 AM-12 noon and more infarction between 12-6 pm. However there was no relation between the time of onset of stroke and various risk-factors of stroke.

  14. [Importance of voice quality evaluation in the assessment of treatment outcome after endolaryngeal microsurgery].

    Science.gov (United States)

    Siupsinskiene, Nora

    2002-01-01

    The aim of the study was to compare subjective and quantitative voice characteristics changes after endolaryngeal microsurgery with respect to different postoperative follow-up term. We evaluated 80 surgically-treated patients aged 14-81 years (mean 42.6+/-13.8 years) with benign vocal cord (VC) lesions (polyps, n=37; cysts, n=16; Reinke's edema, n=18; papilomata, n=9). Patients were evaluated three times - before operation, less than two weeks (mean 1.0+/-0.4) following the operation and more than two weeks (mean 6.5+/-3.9) following the operation. Control group consisted of 122 healthy voice patients. Subjective voice evaluation composed of experts assessment (GRBAS hoarseness scale, visual analogue scale (VAS) of voice quality) and patients self-evaluation (VAS, voice handicap index, and the impression of what repercussions the voice problem has on professional life and emotions). Seven quantitative voice parameters obtained from voice range profile, laryngostroboscopy and registering of maximum phonation time were analyzed as well as overall vocal dysfunction degree (VDD). The data of second postoperative examination were statistically significantly better compared to the first postoperative follow-up (pvoice (G=0) was found for 13.8% (11), quantitatively (VDD=0) for 22.5% (18) of patients, during the second - 63.8% (51) and 53.8% (43). The best results were for patients with vocal cords polyps. The complex voice assessment may be useful for evaluation of voice function recovery and efficacy of surgical treatment.

  15. Voice and Speech after Laryngectomy

    Science.gov (United States)

    Stajner-Katusic, Smiljka; Horga, Damir; Musura, Maja; Globlek, Dubravka

    2006-01-01

    The aim of the investigation is to compare voice and speech quality in alaryngeal patients using esophageal speech (ESOP, eight subjects), electroacoustical speech aid (EACA, six subjects) and tracheoesophageal voice prosthesis (TEVP, three subjects). The subjects reading a short story were recorded in the sound-proof booth and the speech samples…

  16. Voice Quality of Psychological Origin

    Science.gov (United States)

    Teixeira, Antonio; Nunes, Ana; Coimbra, Rosa Lidia; Lima, Rosa; Moutinho, Lurdes

    2008-01-01

    Variations in voice quality are essentially related to modifications of the glottal source parameters, such as: F[subscript 0], jitter, and shimmer. Voice quality is affected by prosody, emotional state, and vocal pathologies. Psychogenic vocal pathology is particularly interesting. In the present case study, the speaker naturally presented a…

  17. Voice handicap index in Swedish.

    Science.gov (United States)

    Ohlsson, Ann-Christine; Dotevall, Hans

    2009-01-01

    The objective of this study was to evaluate a Swedish version of the voice handicap index questionnaire (Sw-VHI). A total of 57 adult, dysphonic patients and 15 healthy controls completed the Sw-VHI and rated the degree of vocal fatigue and hoarseness on visual analogue scales. A perceptual voice evaluation was also performed. Test-retest reliability was analyzed in 38 subjects without voice complaints. Sw-VHI distinguished between dysphonic subjects and controls (P 0.84) and test-retest reliability (intraclass correlation coefficient >0.75) were good. Only moderate or weak correlations were found between Sw-VHI and the subjective and perceptual voice ratings. The data indicate that a difference above 13 points for the total Sw-VHI score and above 6 points for the Sw-VHI subscales is significant for an individual when comparing two different occasions. In conclusion, the Sw-VHI appears to be a robust instrument for assessment of the psycho-social impact of a voice disorder. However, Sw-VHI seems to, at least partly, capture different aspects of voice function to the subjective voice ratings and the perceptual voice evaluation.

  18. Enhancing Author's Voice through Scripting

    Science.gov (United States)

    Young, Chase J.; Rasinski, Timothy V.

    2011-01-01

    The authors suggest using scripting as a strategy to mentor and enhance author's voice in writing. Through gradual release, students use authentic literature as a model for writing with voice. The authors also propose possible extensions for independent practice, integration across content areas, and tips for evaluation.

  19. Voice, Schooling, Inequality, and Scale

    Science.gov (United States)

    Collins, James

    2013-01-01

    The rich studies in this collection show that the investigation of voice requires analysis of "recognition" across layered spatial-temporal and sociolinguistic scales. I argue that the concepts of voice, recognition, and scale provide insight into contemporary educational inequality and that their study benefits, in turn, from paying attention to…

  20. Facing Sound - Voicing Art

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2013-01-01

    This article is based on examples of contemporary audiovisual art, with a special focus on the Tony Oursler exhibition Face to Face at Aarhus Art Museum ARoS in Denmark in March-July 2012. My investigation involves a combination of qualitative interviews with visitors, observations of the audienc......´s interactions with the exhibition and the artwork in the museum space and short analyses of individual works of art based on reception aesthetics and phenomenology and inspired by newer writings on sound, voice and listening....

  1. Voice over IP Security

    CERN Document Server

    Keromytis, Angelos D

    2011-01-01

    Voice over IP (VoIP) and Internet Multimedia Subsystem technologies (IMS) are rapidly being adopted by consumers, enterprises, governments and militaries. These technologies offer higher flexibility and more features than traditional telephony (PSTN) infrastructures, as well as the potential for lower cost through equipment consolidation and, for the consumer market, new business models. However, VoIP systems also represent a higher complexity in terms of architecture, protocols and implementation, with a corresponding increase in the potential for misuse. In this book, the authors examine the

  2. The timing of the onset of puberty, extension of the breeding season, and length of postpartum anestrus in the female mouflon (Ovis gmelini musimon).

    Science.gov (United States)

    Santiago-Moreno, J; Lopez-Sebastian, A; Gonzalez-Bulnes, A; Gomez-Brunet, A; Tortonese, D

    2001-06-01

    The timing of the onset of puberty, duration of seasonal ovulatory activity, and length of postpartum anestrus were studied by means of blood plasma progesterone concentrations in a flock of European female mouflons (Ovis gmelini musimon) maintained in captivity under natural photoperiod (40 degrees 25'N). Concentrations of progesterone in the peripheral blood were determined by radioimmunoassay in samples collected from the jugular vein twice a week. First ovulations in the breeding season were highly synchronized and occurred in mid-October. In contrast, the cessation of ovulatory cycles showed significant variation among females and extended from February to May, depending on age, with 2-yr-old animals exhibiting the longest anovulatory period (P mouflon lambs that reached a minimum threshold body weight (23.8 +/- 0.6 kg) in their first breeding season reached puberty at 8 mo of age. In those with slower growth rates, however, the prepubertal period was extended throughout the first breeding and nonbreeding seasons, reaching puberty during the breeding season of the following year at 19 mo of age and 27 +/- 0.3 kg body weight. Further, attainment of puberty in ewe lambs born in June/July was also delayed until the breeding season of the following year, when animals had reached a threshold body weight at 17 mo of age.

  3. The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands.

    Science.gov (United States)

    Scholl, Joep H G; van Puijenbroek, Eugène P

    2016-12-01

    In pharmacovigilance, the commonly used disproportionality analysis (DPA) in statistical signal detection is known to have its limitations. The aim of this study was to investigate the value of the time to onset (TTO) of ADRs in addition to DPA. We performed a pilot study using individual case safety reports (ICSRs) for three drugs (Cervarix®, nitrofurantoin and simvastatin) from the Lareb spontaneous reporting database. TTO distributions for drug - ADR associations were compared to other ADRs for the same drug and to other drugs for the same ADR using two-sample Anderson-Darling testing. Statistically significant associations were considered true positive (TP) signals if the association was present in the official product information of the drug. Sensitivity and specificity for the TTO method were compared with the DPA method. As a measure of disproportionality, the reporting odds ratio (ROR) was used. In general, sensitivity was lower, and specificity was higher for the TTO method compared to DPA. The TTO method showed similar sensitivity for all three drugs, whereas specificity was lower for Cervarix®. Eight additional TP signals were found using the TTO method compared to DPA. Our study shows that statistical signal detection based on the TTO alone resulted in a limited number of additional signals compared to DPA. We therefore conclude that the TTO method is of limited value for full database statistical screening in our setting. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Lower extremity muscle activation onset times during the transition from double-leg stance to single-leg stance in anterior cruciate ligament injured subjects.

    Science.gov (United States)

    Dingenen, Bart; Janssens, Luc; Luyckx, Thomas; Claes, Steven; Bellemans, Johan; Staes, Filip F

    2015-12-01

    The goal of this study was to evaluate muscle activation onset times (MAOT) of both legs during a transition task from double-leg stance (DLS) to single-leg stance (SLS) in anterior cruciate ligament injured (ACLI) (n=15) and non-injured control subjects (n=15) with eyes open and eyes closed. Significantly delayed MAOT were found in the ACLI group compared to the control group for vastus lateralis, vastus medialis obliquus, hamstrings medial, hamstrings lateral, tibialis anterior, peroneus longus and gastrocnemius in both vision conditions, for gluteus maximus and gluteus medius with eyes open and for tensor fascia latae with eyes closed. Within the ACLI group, delayed MAOT of tibialis anterior with eyes open and gastrocnemius with eyes closed were found in the injured leg compared to the non-injured leg. All other muscles were not significantly different between legs. In conclusion, the ACLI group showed delayed MAOT not only around the knee, but also at the hip and ankle muscles compared to the non-injured control group. No differences between both legs of the ACLI group were found, except for tibialis anterior and gastrocnemius. These findings indirectly support including central nervous system re-education training to target the underlying mechanisms of these altered MAOT after ACL injury.

  5. Effects on vocal range and voice quality of singing voice training: the classically trained female voice.

    Science.gov (United States)

    Pabon, Peter; Stallinga, Rob; Södersten, Maria; Ternström, Sten

    2014-01-01

    A longitudinal study was performed on the acoustical effects of singing voice training under a given study program, using the voice range profile (VRP). Pretraining and posttraining recordings were made of students who participated in a 3-year bachelor singing study program. A questionnaire that included questions on optimal range, register use, classification, vocal health and hygiene, mixing technique, and training goals was used to rate and categorize self-assessed voice changes. Based on the responses, a subgroup of 10 classically trained female voices was selected, which was homogeneous enough for effects of training to be identified. The VRP perimeter contour was analyzed for effects of voice training. Also, a mapping within the VRP of voice quality, as expressed by the crest factor, was used to indicate the register boundaries and to monitor the acoustical consequences of the newly learned vocal technique of "mixed voice." VRPs were averaged across subjects. Findings were compared with the self-assessed vocal changes. Pre/post comparison of the average VRPs showed, in the midrange, (1) a decrease in the VRP area that was associated with the loud chest voice, (2) a reduction of the crest factor values, and (3) a reduction of maximum sound pressure level values. The students' self-evaluations of the voice changes appeared in some cases to contradict the VRP findings. VRPs of individual voices were seen to change over the course of a singing education. These changes were manifest also in the average group. High-resolution computerized recording, complemented with an acoustic register marker, allows a meaningful assessment of some effects of training, on an individual basis and for groups that comprise singers of a specific genre. It is argued that this kind of investigation is possible only within a focused training program, given by a faculty who has agreed on the goals. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  6. Questioning Photovoice Research: Whose Voice?

    Science.gov (United States)

    Evans-Agnew, Robin A; Rosemberg, Marie-Anne S

    2016-07-01

    Photovoice is an important participatory research tool for advancing health equity. Our purpose is to critically review how participant voice is promoted through the photovoice process of taking and discussing photos and adding text/captions. PubMed, Scopus, PsycINFO, and Web of Science databases were searched from the years 2008 to 2014 using the keywords photovoice, photonovella, photovoice and social justice, and photovoice and participatory action research. Research articles were reviewed for how participant voice was (a) analyzed, (b) exhibited in community forums, and (c) disseminated through published manuscripts. Of 21 studies, 13 described participant voice in the data analysis, 14 described participants' control over exhibiting photo-texts, seven manuscripts included a comprehensive set of photo-texts, and none described participant input on choice of manuscript photo-texts. Photovoice designs vary in the advancement of participant voice, with the least advancement occurring in manuscript publication. Future photovoice researchers should expand approaches to advancing participant voice.

  7. Voice quality of psychological origin.

    Science.gov (United States)

    Teixeira, Antonio; Nunes, Ana; Coimbra, Rosa Lídia; Lima, Rosa; Moutinho, Lurdes

    2008-01-01

    Variations in voice quality are essentially related to modifications of the glottal source parameters, such as: F0, jitter, and shimmer. Voice quality is affected by prosody, emotional state, and vocal pathologies. Psychogenic vocal pathology is particularly interesting. In the present case study, the speaker naturally presented a ventricular band voice whereas in a controlled production he was able to use a more normal phonation process. A small corpus was recorded which included sustained vowels and short sentences in both registers. A normal speaker was also recorded in similar tasks. Annotation and extraction of parameters were made using Praat's voice report function. Application of the Hoarseness Diagram to sustained productions situates this case in the pseudo-glottic phonation region. Analysis of several different parameters related to F0, jitter, shimmer, and harmonicity revealed that the speaker with psychogenic voice was capable of controlling certain parameters (e.g. F0 maximum) but was unable to correct others such as shimmer.

  8. Discourses of the Brazilian press about the voice of Lula

    Directory of Open Access Journals (Sweden)

    Carlos Piovezani

    2014-12-01

    Full Text Available Since the announcement of Lula’s throat cancer on October 2011, the risks presented to the voice of Brazil’ former president gave rise to a wide range of comments. Based on Discourse Analysis derived from Michel Pêcheux in this essay we propose to analyze them in terms of their different positions and their distinct meanings. We further undertake a reflexion on certain aspects of Brazilian history, which are preserved in the voice of one of the most important personalities in the country, in order to answer the following questions: Why was Lula’s voice mentioned a number of times? What are the positions and implications of these comments? What role did his voice play in his public speeches, in the composition of his charisma, and in his political success?

  9. Muscular tension and body posture in relation to voice handicap and voice quality in teachers with persistent voice complaints.

    NARCIS (Netherlands)

    Kooijman, P.G.C.; Jong, F.I.C.R.S. de; Oudes, M.J.; Huinck, W.J.; Acht, H. van; Graamans, K.

    2005-01-01

    The aim of this study was to investigate the relationship between extrinsic laryngeal muscular hypertonicity and deviant body posture on the one hand and voice handicap and voice quality on the other hand in teachers with persistent voice complaints and a history of voice-related absenteeism. The st

  10. A First Comparative Study of Oesophageal and Voice Prosthesis Speech Production

    Science.gov (United States)

    Carello, Massimiliana; Magnano, Mauro

    2009-12-01

    The purpose of this work is to evaluate and to compare the acoustic properties of oesophageal voice and voice prosthesis speech production. A group of 14 Italian laryngectomized patients were considered: 7 with oesophageal voice and 7 with tracheoesophageal voice (with phonatory valve). For each patient the spectrogram obtained with the phonation of vowel /a/ (frequency intensity, jitter, shimmer, noise to harmonic ratio) and the maximum phonation time were recorded and analyzed. For the patients with the valve, the tracheostoma pressure, at the time of phonation, was measured in order to obtain important information about the "in vivo" pressure necessary to open the phonatory valve to enable speech.

  11. A First Comparative Study of Oesophageal and Voice Prosthesis Speech Production

    Directory of Open Access Journals (Sweden)

    Massimiliana Carello

    2009-01-01

    Full Text Available The purpose of this work is to evaluate and to compare the acoustic properties of oesophageal voice and voice prosthesis speech production. A group of 14 Italian laryngectomized patients were considered: 7 with oesophageal voice and 7 with tracheoesophageal voice (with phonatory valve. For each patient the spectrogram obtained with the phonation of vowel /a/ (frequency intensity, jitter, shimmer, noise to harmonic ratio and the maximum phonation time were recorded and analyzed. For the patients with the valve, the tracheostoma pressure, at the time of phonation, was measured in order to obtain important information about the “in vivo” pressure necessary to open the phonatory valve to enable speech.

  12. The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: evidence from the United Kingdom Infantile Spasms Study.

    Science.gov (United States)

    O'Callaghan, Finbar J K; Lux, Andrew L; Darke, Katrina; Edwards, Stuart W; Hancock, Eleanor; Johnson, Anthony L; Kennedy, Colin R; Newton, Richard W; Verity, Christopher M; Osborne, John P

    2011-07-01

    Infantile spasms is a severe infantile seizure disorder. Several factors affect developmental outcome, especially the underlying etiology of the spasms. Treatment also affects outcome. Both age at onset of spasms and lead time to treatment (the time from onset of spasms to start of treatment) may be important. We investigated these factors. Developmental assessment using Vineland Adaptive Behaviour Scales (VABS) at 4 years of age in infants enrolled in the United Kingdom Infantile Spasms Study. Date of or age at onset of spasms was obtained prospectively. Lead time to treatment was then categorized into five categories. The effects of lead time to treatment, age of onset of spasms, etiology, and treatment on developmental outcome were investigated using multiple linear regression. Age of onset ranged (77 infants) from 2 months in 21 and not known in 6. Each month of reduction in age at onset of spasms was associated with a 3.1 [95% confidence interval (CI) 0.64-5.5, p = 0.03] decrease, and each increase in category of lead time duration associated with a 3.9 (95% CI 7.3-0.4, p = 0.014) decrease in VABS, respectively. There was a significant interaction between treatment allocation and etiology with the benefit in VABS in those allocated steroid therapy being in children with no identified etiology (coefficient 29.9, p=0.004). Both prompt diagnosis and prompt treatment of infantile spasms may help prevent subsequent developmental delay. Younger infants may be more at risk from the epileptic encephalopathy than older infants. Wiley Periodicals, Inc. © 2011 International League Against Epilepsy.

  13. Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system.

    Science.gov (United States)

    Castellano, Juan M; Bentsen, Agnete H; Sánchez-Garrido, Miguel A; Ruiz-Pino, Francisco; Romero, Magdalena; Garcia-Galiano, David; Aguilar, Enrique; Pinilla, Leonor; Diéguez, Carlos; Mikkelsen, Jens D; Tena-Sempere, Manuel

    2011-09-01

    Kiss1 neurons have recently emerged as a putative conduit for the metabolic gating of reproduction, with leptin being a regulator of hypothalamic Kiss1 expression. Early perturbations of the nutritional status are known to predispose to different metabolic disorders later in life and to alter the timing of puberty; however, the potential underlying mechanisms remain poorly defined. Here we report how changes in the pattern of postnatal feeding affect the onset of puberty and evaluate key hormonal and neuropeptide [Kiss1/kisspeptin (Kp)] alterations linked to these early nutritional manipulations. Female rats were raised in litters of different sizes: small (four pups per dam: overfeeding), normal (12 pups per dam), and large litters (20 pups per litter: underfeeding). Postnatal overfeeding resulted in persistently increased body weight and earlier age of vaginal opening, as an external sign of puberty, together with higher levels of leptin and hypothalamic Kiss1 mRNA. Conversely, postnatal underfeeding caused a persistent reduction in body weight, lower ovarian and uterus weights, and delayed vaginal opening, changes that were paralleled by a decrease in leptin and Kiss1 mRNA levels. Kisspeptin-52 immunoreactivity (Kp-IR) in the hypothalamus displayed similar patterns, with lower numbers of Kp-IR neurons in the arcuate nucleus of postnatally underfed animals, and a trend for increased Kp-positive fibers in the periventricular area of early overfed rats. Yet, gonadotropin responses to Kp at puberty were similar in all groups, except for enhanced responsiveness to low doses of Kp-10 in postnatally underfed rats. In conclusion, our data document that the timing of puberty is sensitive to both overfeeding and subnutrition during early (postnatal) periods and suggest that alterations in hypothalamic expression of Kiss1/kisspeptin may underlie at least part of such programming phenomenon.

  14. Assessments of Voice Use and Voice Quality Among College/University Singing Students Ages 18-24 Through Ambulatory Monitoring With a Full Accelerometer Signal.

    Science.gov (United States)

    Schloneger, Matthew J; Hunter, Eric J

    2017-01-01

    The multiple social and performance demands placed on college/university singers could put their still-developing voices at risk. Previous ambulatory monitoring studies have analyzed the duration, intensity, and frequency (in Hertz) of voice use among such students. Nevertheless, no studies to date have incorporated the simultaneous acoustic voice quality measures into the acquisition of these measures to allow for direct comparison during the same voicing period. Such data could provide greater insight into how young singers use their voices, as well as identify potential correlations between vocal dose and acoustic changes in voice quality. The purpose of this study was to assess the voice use and the estimated voice quality of college/university singing students (18-24 years old, N = 19). Ambulatory monitoring was conducted over three full, consecutive weekdays measuring voice from an unprocessed accelerometer signal measured at the neck. From this signal, traditional vocal dose metrics such as phonation percentage, dose time, cycle dose, and distance dose were analyzed. Additional acoustic measures included perceived pitch, pitch strength, long-term average spectrum slope, alpha ratio, dB sound pressure level 1-3 kHz, and harmonic-to-noise ratio. Major findings from more than 800 hours of recording indicated that among these students (a) higher vocal doses correlated significantly with greater voice intensity, more vocal clarity and less perturbation; and (b) there were significant differences in some acoustic voice quality metrics between nonsinging, solo singing, and choral singing. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  15. Bodies, Spaces, Voices, Silences

    Directory of Open Access Journals (Sweden)

    Donatella Mazzoleni

    2013-07-01

    Full Text Available A good architecture should not only allow functional, formal and technical quality for urban spaces, but also let the voice of the city be perceived, listened, enjoyed. Every city has got its specific sound identity, or “ISO” (R. O. Benenzon, made up of a complex texture of background noises and fluctuation of sound figures emerging and disappearing in a game of continuous fadings. For instance, the ISO of Naples is characterized by a spread need of hearing the sound return of one’s/others voices, by a hate of silence. Cities may fall ill: illness from noise, within super-crowded neighbourhoods, or illness from silence, in the forced isolation of peripheries. The proposal of an urban music therapy denotes an unpublished and innovative enlarged interdisciplinary research path, where architecture, music, medicine, psychology, communication science may converge, in order to work for rebalancing spaces and relation life of the urban collectivity, through the care of body and sound dimensions.

  16. [Speech and voice disorders in Parkinson's disease].

    Science.gov (United States)

    Martnez-Sánchez, Francisco

    2010-11-01

    To examine the voice, speech dysfunction and acoustic parameters typically associated with Parkinson's disease (PD), including the effects on respiration, phonation, articulation and prosody; the effect of treatment with the drug levodopa and deep brain stimulation of the subthalamic nucleus is also examined. One of the features of PD is the alteration of voice and speech. The motor deficits associated with PD adversely affect the major systems that govern speech motor control including respiration, phonation, and articulation. The speech deficits related to PD are often called hypokinetic dysarthria and can be characterized by monopitch, mono-loudness, reduced stress, imprecise consonants, and inappropriate silences. Numerous studies have documented these changes using a wide variety of acoustic measures. Acoustic correlates of PD have a potential to provide useful biomarkers and sensitive methods for the early detection of the onset, progression, and severity of disease states, as well as providing a means to objectively track symptomatic changes and to assess the efficacy of pharmacological and surgical treatments.

  17. Crossing Cultures with Multi-Voiced Journals

    Science.gov (United States)

    Styslinger, Mary E.; Whisenant, Alison

    2004-01-01

    In this article, the authors discuss the benefits of using multi-voiced journals as a teaching strategy in reading instruction. Multi-voiced journals, an adaptation of dual-voiced journals, encourage responses to reading in varied, cultured voices of characters. It is similar to reading journals in that they prod students to connect to the lives…

  18. The stability of locus equation slopes across stop consonant voicing/aspiration

    Science.gov (United States)

    Sussman, Harvey M.; Modarresi, Golnaz

    2001-05-01

    The consistency of locus equation slopes as phonetic descriptors of stop place in CV sequences across voiced and voiceless aspirated stops was explored in the speech of five male speakers of American English and two male speakers of Persian. Using traditional locus equation measurement sites for F2 onsets, voiceless labial and coronal stops had significantly lower locus equation slopes relative to their voiced counterparts, whereas velars failed to show voicing differences. When locus equations were derived using F2 onsets for voiced stops that were measured closer to the stop release burst, comparable to the protocol for measuring voiceless aspirated stops, no significant effects of voicing/aspiration on locus equation slopes were observed. This methodological factor, rather than an underlying phonetic-based explanation, provides a reasonable account for the observed flatter locus equation slopes of voiceless labial and coronal stops relative to voiced cognates reported in previous studies [Molis et al., J. Acoust. Soc. Am. 95, 2925 (1994); O. Engstrand and B. Lindblom, PHONUM 4, 101-104]. [Work supported by NIH.

  19. Lexical frequency and voice assimilation.

    Science.gov (United States)

    Ernestus, Mirjam; Lahey, Mybeth; Verhees, Femke; Baayen, R Harald

    2006-08-01

    Acoustic duration and degree of vowel reduction are known to correlate with a word's frequency of occurrence. The present study broadens the research on the role of frequency in speech production to voice assimilation. The test case was regressive voice assimilation in Dutch. Clusters from a corpus of read speech were more often perceived as unassimilated in lower-frequency words and as either completely voiced (regressive assimilation) or, unexpectedly, as completely voiceless (progressive assimilation) in higher-frequency words. Frequency did not predict the voice classifications over and above important acoustic cues to voicing, suggesting that the frequency effects on the classifications were carried exclusively by the acoustic signal. The duration of the cluster and the period of glottal vibration during the cluster decreased while the duration of the release noises increased with frequency. This indicates that speakers reduce articulatory effort for higher-frequency words, with some acoustic cues signaling more voicing and others less voicing. A higher frequency leads not only to acoustic reduction but also to more assimilation.

  20. Regular inhaled corticosteroids in adult-onset asthma and the risk for future cancer: a population-based cohort study with proper person-time analysis

    Directory of Open Access Journals (Sweden)

    Kok VC

    2015-03-01

    Full Text Available Victor C Kok,1,2 Jorng-Tzong Horng,2,3 Hsu-Kai Huang,3 Tsung-Ming Chao,4 Ya-Fang Hong5 1Division of Medical Oncology, Department of Internal Medicine, Kuang Tien General Hospital, Taichung, Taiwan; 2Department of Biomedical Informatics, Asia University Taiwan, Taichung, Taiwan; 3Department of Computer Science and Information Engineering, National Central University, Jhongli, Taiwan; 4Statistics Unit, Department of Applied Geomatics, Chien Hsin University, Jhongli, Taiwan; 5Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan Background: Recent studies have shown that inhaled corticosteroids (ICS can exert anti-inflammatory effects for chronic airway diseases, and several observational studies suggest that they play a role as cancer chemopreventive agents, particularly against lung cancer. We aimed to examine whether regular ICS use was associated with a reduced risk for future malignancy in patients with newly diagnosed adult-onset asthma. Methods: We used a population-based cohort study between 2001 and 2008 with appropriate person-time analysis. Participants were followed up until the first incident of cancer, death, or to the end of 2008. The Cox model was used to derive an adjusted hazard ratio (aHR for cancer development. Kaplan–Meier cancer-free survival curves of two groups were compared. Results: The exposed group of 2,117 regular ICS users and the nonexposed group of 17,732 non-ICS users were assembled. After 7,365 (mean, 3.5 years; standard deviation 2.1 and 73,789 (mean, 4.1 years; standard deviation 2.4 person-years of follow-up for the ICS users and the comparator group of non-ICS users, respectively, the aHR for overall cancer was nonsignificantly elevated at 1.33 with 95% confidence interval (CI, 1.00–1.76, P=0.0501. The Kaplan–Meier curves for overall cancer-free proportions of both groups were not significant (log-rank, P=0.065. Synergistic interaction of concurrent presence of regular ICS use was

  1. A simplified prevention bundle with dual hand hygiene audit reduces early-onset ventilator-associated pneumonia in cardiovascular surgery units: An interrupted time-series analysis.

    Science.gov (United States)

    Su, Kang-Cheng; Kou, Yu Ru; Lin, Fang-Chi; Wu, Chieh-Hung; Feng, Jia-Yih; Huang, Shiang-Fen; Shiung, Tao-Fen; Chung, Kwei-Chun; Tung, Yu-Hsiu; Yang, Kuang-Yao; Chang, Shi-Chuan

    2017-01-01

    To investigate the effect of a simplified prevention bundle with alcohol-based, dual hand hygiene (HH) audit on the incidence of early-onset ventilation-associated pneumonia (VAP). This 3-year, quasi-experimental study with interrupted time-series analysis was conducted in two cardiovascular surgery intensive care units in a medical center. Unaware external HH audit (eHH) performed by non-unit-based observers was a routine task before and after bundle implementation. Based on the realistic ICU settings, we implemented a 3-component bundle, which included: a compulsory education program, a knowing internal HH audit (iHH) performed by unit-based observers, and a standardized oral care (OC) protocol with 0.1% chlorhexidine gluconate. The study periods comprised 4 phases: 12-month pre-implementation phase 1 (eHH+/education-/iHH-/OC-), 3-month run-in phase 2 (eHH+/education+/iHH+/OC+), 15-month implementation phase 3 (eHH+/education+/iHH+/OC+), and 6-month post-implementation phase 4 (eHH+/education-/iHH+/OC-). A total of 2553 ventilator-days were observed. VAP incidences (events/1000 ventilator days) in phase 1-4 were 39.1, 40.5, 15.9, and 20.4, respectively. VAP was significantly reduced by 59% in phase 3 (vs. phase 1, incidence rate ratio [IRR] 0.41, P = 0.002), but rebounded in phase 4. Moreover, VAP incidence was inversely correlated to compliance of OC (r2 = 0.531, P = 0.001) and eHH (r2 = 0.878, P audit provides better improvement in HH practice. Accordingly, we suggest dual HH audit and consistent bundle performance does matter in quality-of-care VAP prevention.

  2. Hearing performance and voice acoustics of cochlear implanted children.

    Science.gov (United States)

    Coelho, Ana Cristina; Brasolotto, Alcione Ghedino; Bevilacqua, Maria Cecília; Moret, Adriane Lima Mortari; Bahmad Júnior, Fayez

    2016-01-01

    The voice of hearing-impaired individuals has been described extensively, and exhibits abnormalities in quality, articulation and resonance. Having an understanding of the aspects that may have an impact on voice characteristics of cochlear implant users is important for users and for professionals in this field. To verify the existence of correlation between age, time of device use, voice detection threshold, hearing category score and language category score with acoustic data of voices of cochlear implanted children. Retrospective study. Fifty-one children ranging in age from 3 years to 5 years and 11 months who unilaterally used cochlear implants participated. Acoustic analysis of the sustained vowel/a/, sequential speech and spontaneous speech was performed. The results were correlated with demographic data and hearing test results. Children with worse voice detection threshold showed higher frequency in the sustained vowel (p≤0.001) and in the spontaneous speech (p≤0.005). There was a correlation between the voice detection threshold and the frequency values of the sustained vowel and spontaneous speech of the studied population. Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  3. Internet-Based System for Voice Communication With the ISS

    Science.gov (United States)

    Chamberlain, James; Myers, Gerry; Clem, David; Speir, Terri

    2005-01-01

    The Internet Voice Distribution System (IVoDS) is a voice-communication system that comprises mainly computer hardware and software. The IVoDS was developed to supplement and eventually replace the Enhanced Voice Distribution System (EVoDS), which, heretofore, has constituted the terrestrial subsystem of a system for voice communications among crewmembers of the International Space Station (ISS), workers at the Payloads Operations Center at Marshall Space Flight Center, principal investigators at diverse locations who are responsible for specific payloads, and others. The IVoDS utilizes a communication infrastructure of NASA and NASArelated intranets in addition to, as its name suggests, the Internet. Whereas the EVoDS utilizes traditional circuitswitched telephony, the IVoDS is a packet-data system that utilizes a voice over Internet protocol (VOIP). Relative to the EVoDS, the IVoDS offers advantages of greater flexibility and lower cost for expansion and reconfiguration. The IVoDS is an extended version of a commercial Internet-based voice conferencing system that enables each user to participate in only one conference at a time. In the IVoDS, a user can receive audio from as many as eight conferences simultaneously while sending audio to one of them. The IVoDS also incorporates administrative controls, beyond those of the commercial system, that provide greater security and control of the capabilities and authorizations for talking and listening afforded to each user.

  4. Voice and speech changes in various phases of menstrual cycle.

    Science.gov (United States)

    Çelik, Öner; Çelik, Aygen; Ateşpare, Altay; Boyacı, Zerrin; Çelebi, Saban; Gündüz, Tonguç; Aksungar, Fehime Benli; Yelken, Kürşat

    2013-09-01

    The reproductive system in females undergoes a regular cyclic change known as the menstrual cycle. Laryngeal changes are evident and fluctuate systematically during the reproductive years with the menstrual cycle. The impact of estrogens in concert with progesterone produces the characteristics of the female voice, with a fundamental frequency (F(0)) higher than that of male. To characterize changes in voice and speech in adolescent females in different phases of the menstrual cycle--during menstruation, after menstruation, mid-menstrual cycle, and premenstruation. Sixteen adult females who were nonusers of oral contraceptives participated in a cross-sectional study of menstrual cycle influences on voicing and speaking tasks. Acoustic analysis (F(0), intensity, perturbation measurements [jitter and shimmer], and harmonic-to-noise ratio), maximum phonation time (MPT), s/z ratio, and perceptual assessments (grade [G], roughness [R], breathiness [B], asthenia [A], and strain [S] [GRBAS] and Voice Handicap Index-10 [VHI-10]) scales were performed during all phases. None of the acoustic analysis parameters and MPT and s/z ratio measurements revealed statistically significant difference (P > 0.05). Perceptual voice assessment scales either clinician based or patients self-evaluated showed significant differences among phases (P menstrual cycle. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  5. Investigating the Effects of Smoking on Young Adult Male Voice by Using Multidimensional Methods.

    Science.gov (United States)

    Pinar, Dogan; Cincik, Hakan; Erkul, Evren; Gungor, Atila

    2016-11-01

    Smoking is one of the most common harmful habits in the world, especially common among young adult male population in Turkey. The purpose of this study was to evaluate the effect of smoking on the young adults' male voice using multidimensional voice assessment methods. This is a case-control study. The study included 109 young adult men, 51 nonsmokers and 58 smokers between the ages of 20 and 34 years. The voice evaluation protocol consisted of voice handicap index (VHI), maximum phonation time (MPT), and perceptual, acoustic, and videostroboscopic analyses. A statistically significant increase for physical, physiological, and total scores of VHI was found in smokers group (P smoking and increased vocal fold erythema (P smoking habits. Subjective symptoms of smoking on voice appear to occur earlier than objective findings. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  6. Perceptions of Competence, Strength, and Age Influence Voters to Select Leaders with Lower-Pitched Voices.

    Directory of Open Access Journals (Sweden)

    Casey A Klofstad

    Full Text Available Voters prefer leaders with lower-pitched voices because they are perceived as stronger, having greater physical prowess, more competent, and having greater integrity. An alternative hypothesis that has yet to be tested is that lower-pitched voices are perceived as older and thus wiser and more experienced. Here the relationships between candidate voice pitch, candidate age, and electoral success are examined with two experiments. Study 1 tests whether voters discriminate on candidate age. The results show that male and female candidates in their 40s and 50s, the time in the lifecycle when voice pitch is at its lowest, are preferred over candidates in their 30s, 60s, and 70s. Study 2 shows that the preference for leaders with lower-pitched voices correlates with the perception that speakers with lower voices are stronger, more competent, and older, but the influence of perception of age on vote choice is the weakest of the three.

  7. Time to onset of analgesia and analgesic efficacy of effervescent acetaminophen 1000 mg compared to tablet acetaminophen 1000 mg in postoperative dental pain: a single-dose, double-blind, randomized, placebo-controlled study.

    Science.gov (United States)

    Møller, P L; Nørholt, S E; Ganry, H E; Insuasty, J H; Vincent, F G; Skoglund, L A; Sindet-Pedersen, S

    2000-04-01

    This randomized, double-blind, placebo-controlled study compared the time to onset of analgesia and the analgesic efficacy of two formulations of acetaminophen 1000 mg--an effervescent solution and tablet--in 242 patients with moderate or severe pain following dental surgery. Onset of analgesia was determined using a two-stopwatch procedure. Analgesia was assessed over a 4-hour period. Treatments were compared using standard indexes of pain intensity and pain relief and summary measures. Both acetaminophen formulations were significantly more effective than their corresponding placebo for all efficacy assessments. The median time to onset of analgesia was significantly shorter with effervescent acetaminophen (20 minutes) compared to tablet acetaminophen (45 minutes). During the first 45 minutes after administration, effervescent acetaminophen was significantly more effective at each scheduled assessment time than tablet acetaminophen. The median time to meaningful pain relief was significantly shorter with effervescent acetaminophen (45 minutes) compared to tablet acetaminophen (60 minutes). At 4 hours after administration, the pain relief was significantly better with tablet acetaminophen than with effervescent acetaminophen. No other significant differences were observed between the active treatments. In conclusion, effervescent acetaminophen produces a significantly faster onset of analgesia than tablet acetaminophen.

  8. Evaluation of the Implementation of a Rapid Response Treatment Protocol for Patients with Acute Onset Stroke: Can We Increase the Number of Patients Treated and Shorten the Time Needed

    Directory of Open Access Journals (Sweden)

    Rajiv Advani

    2014-06-01

    Full Text Available Aims: This study aims to evaluate the implementation of a rapid response treatment protocol for patients presenting with acute onset ischemic stroke. Improvements of routines surrounding the admission and treatment of patients with intravenous thrombolysis (IVT, such as door-to-needle (DTN times, and increasing the numbers of patients treated are discussed. Methods: We conducted a retrospective analysis of all patients (n = 320 treated with IVT for acute onset ischemic stroke at the Stavanger University Hospital, Norway, between 2003 and 2012. In 2009, a succession of changes to pre- and intra-hospital routines were made as well as an improvement in the education of primary health care physicians, nurses and paramedics involved in the treatment of acute onset stroke patients (rapid response treatment protocol. Analyses of DTN times, onset-to-needle times and the number of patients treated per year were carried out to ascertain the effect of the changes made. The primary aim was to analyze DTN times to look for any changes, and the secondary aim was to analyze changes in the number of patients treated per year. Results: In the years after the implementation of the rapid treatment protocol, we saw an improvement in the median DTN time with a decrease from 73 to 50 min in the first year (p = 0.03, a decrease of 45 min in the second year (p = 0.01 and a decrease of 31 min in the third year (p Conclusions: The implementation of the rapid treatment protocol for acute onset ischemic stroke patients led to a significant decrease in the DTN time at our center. These improvements also produced an increase in the number of patients treated per year. The extension of the therapeutic window from 3 to 4.5 h for the use of intravenous recombinant tissue plasminogen activator also played a role in the increased treatment numbers.

  9. Emotional cues during simultaneous face and voice processing: electrophysiological insights.

    Directory of Open Access Journals (Sweden)

    Taosheng Liu

    Full Text Available Both facial expression and tone of voice represent key signals of emotional communication but their brain processing correlates remain unclear. Accordingly, we constructed a novel implicit emotion recognition task consisting of simultaneously presented human faces and voices with neutral, happy, and angry valence, within the context of recognizing monkey faces and voices task. To investigate the temporal unfolding of the processing of affective information from human face-voice pairings, we recorded event-related potentials (ERPs to these audiovisual test stimuli in 18 normal healthy subjects; N100, P200, N250, P300 components were observed at electrodes in the frontal-central region, while P100, N170, P270 were observed at electrodes in the parietal-occipital region. Results indicated a significant audiovisual stimulus effect on the amplitudes and latencies of components in frontal-central (P200, P300, and N250 but not the parietal occipital region (P100, N170 and P270. Specifically, P200 and P300 amplitudes were more positive for emotional relative to neutral audiovisual stimuli, irrespective of valence, whereas N250 amplitude was more negative for neutral relative to emotional stimuli. No differentiation was observed between angry and happy conditions. The results suggest that the general effect of emotion on audiovisual processing can emerge as early as 200 msec (P200 peak latency post stimulus onset, in spite of implicit affective processing task demands, and that such effect is mainly distributed in the frontal-central region.

  10. Emotional cues during simultaneous face and voice processing: electrophysiological insights.

    Science.gov (United States)

    Liu, Taosheng; Pinheiro, Ana; Zhao, Zhongxin; Nestor, Paul G; McCarley, Robert W; Niznikiewicz, Margaret A

    2012-01-01

    Both facial expression and tone of voice represent key signals of emotional communication but their brain processing correlates remain unclear. Accordingly, we constructed a novel implicit emotion recognition task consisting of simultaneously presented human faces and voices with neutral, happy, and angry valence, within the context of recognizing monkey faces and voices task. To investigate the temporal unfolding of the processing of affective information from human face-voice pairings, we recorded event-related potentials (ERPs) to these audiovisual test stimuli in 18 normal healthy subjects; N100, P200, N250, P300 components were observed at electrodes in the frontal-central region, while P100, N170, P270 were observed at electrodes in the parietal-occipital region. Results indicated a significant audiovisual stimulus effect on the amplitudes and latencies of components in frontal-central (P200, P300, and N250) but not the parietal occipital region (P100, N170 and P270). Specifically, P200 and P300 amplitudes were more positive for emotional relative to neutral audiovisual stimuli, irrespective of valence, whereas N250 amplitude was more negative for neutral relative to emotional stimuli. No differentiation was observed between angry and happy conditions. The results suggest that the general effect of emotion on audiovisual processing can emerge as early as 200 msec (P200 peak latency) post stimulus onset, in spite of implicit affective processing task demands, and that such effect is mainly distributed in the frontal-central region.

  11. Biologically inspired robust onset detection

    Science.gov (United States)

    Smith, Leslie S.

    2003-04-01

    Onsets are rapid increases in signal strength. The common onset time in different frequency bands provides an important cue for dynamically grouping sound energy, and hence for sound streaming. Onsets are important for segmenting sounds [Smith, J. New Music Res. 23, 11-23 (1994)] and for determining where to measure IIDs and ITDs for the sound direction finding [Smith, J. Acoust. Soc. Am. 111, 2467 (2002)]. Effective onset detection requires low latency and the capacity to cope with wide variation in the dynamic range. Many neurons in the auditory brainstem are sensitive to onsets. The system filters sound into cochlea-like bands (using a Gammatone filterbank), then spike codes positive-going zero-crossings. A wide dynamic range is achieved by using multiple spike trains per filter band, each with different sensitivity. The spike trains from each band innervate a leaky integrate-and-fire neuron. The excitatory synapses from the spike trains are fast and depressing: the shunting inhibitory synapses are facilitating and slower. The combined effect is that the neuron produces a single spike for each onset over a wide dynamic range with very low latency. The use of both inhibitory and excitatory synapses improves onset detection over purely excitatory synapses, leading to a better sound direction finding than previously reported.

  12. Voice Habits and Behaviors: Voice Care Among Flamenco Singers.

    Science.gov (United States)

    Garzón García, Marina; Muñoz López, Juana; Y Mendoza Lara, Elvira

    2017-03-01

    The purpose of this study is to analyze the vocal behavior of flamenco singers, as compared with classical music singers, to establish a differential vocal profile of voice habits and behaviors in flamenco music. Bibliographic review was conducted, and the Singer's Vocal Habits Questionnaire, an experimental tool designed by the authors to gather data regarding hygiene behavior, drinking and smoking habits, type of practice, voice care, and symptomatology perceived in both the singing and the speaking voice, was administered. We interviewed 94 singers, divided into two groups: the flamenco experimental group (FEG, n = 48) and the classical control group (CCG, n = 46). Frequency analysis, a Likert scale, and discriminant and exploratory factor analysis were used to obtain a differential profile for each group. The FEG scored higher than the CCG in speaking voice symptomatology. The FEG scored significantly higher than the CCG in use of "inadequate vocal technique" when singing. Regarding voice habits, the FEG scored higher in "lack of practice and warm-up" and "environmental habits." A total of 92.6% of the subjects classified themselves correctly in each group. The Singer's Vocal Habits Questionnaire has proven effective in differentiating flamenco and classical singers. Flamenco singers are exposed to numerous vocal risk factors that make them more prone to vocal fatigue, mucosa dehydration, phonotrauma, and muscle stiffness than classical singers. Further research is needed in voice training in flamenco music, as a means to strengthen the voice and enable it to meet the requirements of this musical genre. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  13. Voices of the Unheard

    DEFF Research Database (Denmark)

    Matthiesen, Noomi Christine Linde

    2014-01-01

    . They were in two different classes at both schools, i.e. four classes in total. The families were followed for 18 months. Formal interviews were conducted with mothers and teachers, parent-teacher conferences were recorded, participant observations were conducted in classrooms and playgrounds, afterschool...... is that Somali diaspora parents (and with special focus on mothers as these where the parents who took most responsibility in the four cases of this research) have difficulty expressing their opinions as there are structural, historical and social dynamics that create conditions in which their voices...... are silenced, or at least restricted significantly, resulting in marginalizing consequences. The focus in each article is on here-and-now interactional dynamics but in order to understand these constitutive negotiations, it is argued that the analysis must be situated in a description of the constituted...

  14. Passing on power & voice

    DEFF Research Database (Denmark)

    Noer, Vibeke Røn; Nielsen, Cathrine Sand

    2014-01-01

    . The education lasts for 3,5 years and the landmark of the educational model is the continuously shifts between teaching in classroom and teaching in clinical practice. Clinical teaching takes place at approved clinical placement institutions in hospitals and in the social and health care services outside...... intention of gaining knowledge about other possible ways to perform the education. The class, named the E-class, followed what in the field was named ‘an experimental educational model based on experienced-based learning’ (Nielsen et al. 2011). The experiential educational model is argued as an experiment.......aspx Higher degree of student involvement in planning as well as teaching was in the field presented as a part of ‘the overall educational approach’. In the course ‘Acute, Critical Nursing & Terminal, Palliative Care’ this was transferred into an innovative pedagogy with intend to pass on power and voice...

  15. Voice stress analysis

    Science.gov (United States)

    Brenner, Malcolm; Shipp, Thomas

    1988-01-01

    In a study of the validity of eight candidate voice measures (fundamental frequency, amplitude, speech rate, frequency jitter, amplitude shimmer, Psychological Stress Evaluator scores, energy distribution, and the derived measure of the above measures) for determining psychological stress, 17 males age 21 to 35 were subjected to a tracking task on a microcomputer CRT while parameters of vocal production as well as heart rate were measured. Findings confirm those of earlier studies that increases in fundamental frequency, amplitude, and speech rate are found in speakers involved in extreme levels of stress. In addition, it was found that the same changes appear to occur in a regular fashion within a more subtle level of stress that may be characteristic, for example, of routine flying situations. None of the individual speech measures performed as robustly as did heart rate.

  16. Voice over IP

    OpenAIRE

    Mantula, Juha

    2006-01-01

    Tämä opinnäytetyö käsittelee Voice over Internet Protocol -tekniikkaa ja sen tuomia mahdollisuuksia yrityselämässä. Teoriaosa käsittelee VoIP:n kannalta tärkeitä pro-tokollia ja standardeja, VoIP:n ominaisuuksia sekä esittelee erilaisia puheohjelmia, jotka käyttävät VoIP-tekniikkaa hyväkseen. Empiirinen osuus tutkii Viestintä Ky Pitkärannan Skype-ohjelman käyttöä. Työn tarkoituksena on selvittää VoIP:n hyviä ja huonoja puolia ja sitä kuinka tek-niikkaa voidaan käyttää hyväksi päivittäisessä ...

  17. Voice and choice by delegation.

    Science.gov (United States)

    van de Bovenkamp, Hester; Vollaard, Hans; Trappenburg, Margo; Grit, Kor

    2013-02-01

    In many Western countries, options for citizens to influence public services are increased to improve the quality of services and democratize decision making. Possibilities to influence are often cast into Albert Hirschman's taxonomy of exit (choice), voice, and loyalty. In this article we identify delegation as an important addition to this framework. Delegation gives individuals the chance to practice exit/choice or voice without all the hard work that is usually involved in these options. Empirical research shows that not many people use their individual options of exit and voice, which could lead to inequality between users and nonusers. We identify delegation as a possible solution to this problem, using Dutch health care as a case study to explore this option. Notwithstanding various advantages, we show that voice and choice by delegation also entail problems of inequality and representativeness.

  18. The Christian voice in philosophy

    Directory of Open Access Journals (Sweden)

    Stuart Fowler

    1982-03-01

    Full Text Available In this paper the Rev. Stuart Fowler outlines a Christian voice in Philosophy and urges the Christian philosopher to investigate his position and his stance with integrity and honesty.

  19. Voice Force tulekul / Tõnu Ojala

    Index Scriptorium Estoniae

    Ojala, Tõnu, 1969-

    2005-01-01

    60. sünnipäeva tähistava Tallinna Tehnikaülikooli Akadeemilise Meeskoori juubelihooaja üritusest - a capella pop-gruppide festivalist Voice Force (kontserdid 12. nov. klubis Parlament ja 3. dets. Vene Kultuurikeskuses)

  20. Voice Force tulekul / Tõnu Ojala

    Index Scriptorium Estoniae

    Ojala, Tõnu, 1969-

    2005-01-01

    60. sünnipäeva tähistava Tallinna Tehnikaülikooli Akadeemilise Meeskoori juubelihooaja üritusest - a capella pop-gruppide festivalist Voice Force (kontserdid 12. nov. klubis Parlament ja 3. dets. Vene Kultuurikeskuses)

  1. {sup 18}F-FDG PET uptake in the pre-Huntington disease caudate affects the time-to-onset independently of CAG expansion size

    Energy Technology Data Exchange (ETDEWEB)

    Ciarmiello, Andrea; Giovacchini, Giampiero; Bruselli, Laura [Nuclear Medicine Department, S. Andrea Hospital, La Spezia (Italy); Orobello, Sara; Elifani, Francesca; Squitieri, Ferdinando [Centre for Neurogenetics and Rare Diseases, IRCCS Neuromed, Pozzilli, IS (Italy)

    2012-06-15

    To test in a longitudinal follow-up study whether basal glucose metabolism in subjects with a genetic risk of Huntington disease (HD) may influence the onset of manifest symptoms. The study group comprised 43 presymptomatic (preHD) subjects carrying the HD mutation. They underwent a {sup 18}F-FDG PET scan and were prospectively followed-up for at least 5 years using the unified HD rating scale to detect clinical changes. Multiple regression analysis included subject's age, CAG mutation size and glucose uptake as variables in a model to predict age at onset. Of the 43 preHD subjects who manifested motor symptoms, suggestive of HD, after 5 years from the PET scan, 26 showed a mean brain glucose uptake below the cut-off of 1.0493 in the caudate, significantly lower than the 17 preHD subjects who remained symptom-free (P < 0.0001). This difference was independent of mutation size. Measurement of brain glucose uptake improved the CAG repeat number and age-based model for predicting age at onset by 37 %. A reduced level of glucose metabolism in the brain caudate may represent a predisposing factor that contributes to the age at onset of HD in preHD subjects, in addition to the mutation size. (orig.)

  2. Is there a connection between weather at departure sites, onset of migration and timing of soaring-bird autumn migration in Israel?

    NARCIS (Netherlands)

    Shamoun-Baranes, J.; van Loon, E.E.; Alon, D.; Alpert, P.; Yom-Tov, Y.; Leshem, Y.

    2006-01-01

    Aims Different aspects of soaring-bird migration are influenced by weather. However, the relationship between weather and the onset of soaring-bird migration, particularly in autumn, is not clear. Although long-term migration counts are often unavailable near the breeding areas of many soaring birds

  3. Feature Extraction of Voice Segments Using Cepstral Analysis for Voice Regeneration

    OpenAIRE

    Banerjee, P. S.; Baisakhi Chakraborty; Jaya Banerjee

    2015-01-01

    Even though a lot of work has been done on areas of speech to text and vice versa or voice detection or similarity analysis of two voice samples but very less emphasis has be given to voice regeneration. General algorithms for distinct voice checking for two voice sources paved way for our endeavor in reconstructing the voice from the source voice samples provided. By utilizing these algorithms and putting further stress on the feature extraction part we tried to fabricate the source voice wi...

  4. Voice Simulation in Nursing Education.

    Science.gov (United States)

    Kepler, Britney B; Lee, Heeyoung; Kane, Irene; Mitchell, Ann M

    2016-01-01

    The goal of this study was to improve prelicensure nursing students' attitudes toward and self-efficacy related to delivering nursing care to patients with auditory hallucinations. Based on the Hearing Voices That Are Distressing curriculum, 87 participants were instructed to complete 3 tasks while wearing headphones delivering distressing voices. Comparing presimulation and postsimulation results, this study suggests that the simulation significantly improved attitudes toward patients with auditory hallucinations; however, self-efficacy related to caring for these patients remained largely unchanged.

  5. Work-related voice disorder

    OpenAIRE

    Paulo Eduardo Przysiezny; Luciana Tironi Sanson Przysiezny

    2015-01-01

    INTRODUCTION: Dysphonia is the main symptom of the disorders of oral communication. However, voice disorders also present with other symptoms such as difficulty in maintaining the voice (asthenia), vocal fatigue, variation in habitual vocal fundamental frequency, hoarseness, lack of vocal volume and projection, loss of vocal efficiency, and weakness when speaking. There are several proposals for the etiologic classification of dysphonia: functional, organofunctional, organic, and work-related...

  6. Tracheostomy cannulas and voice prosthesis.

    Science.gov (United States)

    Kramp, Burkhard; Dommerich, Steffen

    2009-01-01

    Cannulas and voice prostheses are mechanical aids for patients who had to undergo tracheotomy or laryngectomy for different reasons. For better understanding of the function of those artificial devices, first the indications and particularities of the previous surgical intervention are described in the context of this review. Despite the established procedure of percutaneous dilatation tracheotomy e.g. in intensive care units, the application of epithelised tracheostomas has its own position, especially when airway obstruction is persistent (e.g. caused by traumata, inflammations, or tumors) and a longer artificial ventilation or special care of the patient are required. In order to keep the airways open after tracheotomy, tracheostomy cannulas of different materials with different functions are available. For each patient the most appropriate type of cannula must be found. Voice prostheses are meanwhile the device of choice for rapid and efficient voice rehabilitation after laryngectomy. Individual sizes and materials allow adaptation of the voice prostheses to the individual anatomical situation of the patients. The combined application of voice prostheses with HME (Head and Moisture Exchanger) allows a good vocal as well as pulmonary rehabilitation. Precondition for efficient voice prosthesis is the observation of certain surgical principles during laryngectomy. The duration of the prosthesis mainly depends on material properties and biofilms, mostly consisting of funguses and bacteries. The quality of voice with valve prosthesis is clearly superior to esophagus prosthesis or electro-laryngeal voice. Whenever possible, tracheostoma valves for free-hand speech should be applied. Physicians taking care of patients with speech prostheses after laryngectomy should know exactly what to do in case the device fails or gets lost.

  7. Sensory Processing: Advances in Understanding Structure and Function of Pitch-Shifted Auditory Feedback in Voice Control

    Directory of Open Access Journals (Sweden)

    Charles R Larson

    2016-02-01

    Full Text Available The pitch-shift paradigm has become a widely used method for studying the role of voice pitch auditory feedback in voice control. This paradigm introduces small, brief pitch shifts in voice auditory feedback to vocalizing subjects. The perturbations trigger a reflexive mechanism that counteracts the change in pitch. The underlying mechanisms of the vocal responses are thought to reflect a negative feedback control system that is similar to constructs developed to explain other forms of motor control. Another use of this technique requires subjects to voluntarily change the pitch of their voice when they hear a pitch shift stimulus. Under these conditions, short latency responses are produced that change voice pitch to match that of the stimulus. The pitch-shift technique has been used with magnetoencephalography (MEG and electroencephalography (EEG recordings, and has shown that at vocal onset there is normally a suppression of neural activity related to vocalization. However, if a pitch-shift is also presented at voice onset, there is a cancellation of this suppression, which has been interpreted to mean that one way in which a person distinguishes self-vocalization from vocalization of others is by a comparison of the intended voice and the actual voice. Studies of the pitch shift reflex in the fMRI environment show that the superior temporal gyrus (STG plays an important role in the process of controlling voice F0 based on auditory feedback. Additional studies using fMRI for effective connectivity modeling show that the left and right STG play critical roles in correcting for an error in voice production. While both the left and right STG are involved in this process, a feedback loop develops between left and right STG during perturbations, in which the left to right connection becomes stronger, and a new negative right to left connection emerges along with the emergence of other feedback loops within the cortical network tested.

  8. The impact of voice on speech realization

    Directory of Open Access Journals (Sweden)

    Jelka Breznik

    2014-12-01

    Full Text Available The study discusses spoken literary language and the impact of voice on speech realization. The voice consists of a sound made by a human being using the vocal folds for talking, singing, laughing, crying, screaming… The human voice is specifically the part of human sound production in which the vocal folds (vocal cords are the primary sound source. Our voice is our instrument and identity card. How does the voice (voice tone affect others and how do they respond, positively or negatively? How important is voice (voice tone in communication process? The study presents how certain individuals perceive voice. The results of the research on the relationships between the spoken word, excellent speaker, voice and description / definition / identification of specific voices done by experts in the field of speech and voice as well as non-professionals are presented. The study encompasses two focus groups. One consists of amateurs (non-specialists in the field of speech or voice who have no knowledge in this field and the other consists of professionals who work with speech or language or voice. The questions were intensified from general to specific, directly related to the topic. The purpose of such a method of questioning was to create relaxed atmosphere, promote discussion, allow participants to interact, complement, and to set up self-listening and additional comments.

  9. Double Fourier analysis for Emotion Identification in Voiced Speech

    Science.gov (United States)

    Sierra-Sosa, D.; Bastidas, M.; Ortiz P., D.; Quintero, O. L.

    2016-04-01

    We propose a novel analysis alternative, based on two Fourier Transforms for emotion recognition from speech. Fourier analysis allows for display and synthesizes different signals, in terms of power spectral density distributions. A spectrogram of the voice signal is obtained performing a short time Fourier Transform with Gaussian windows, this spectrogram portraits frequency related features, such as vocal tract resonances and quasi-periodic excitations during voiced sounds. Emotions induce such characteristics in speech, which become apparent in spectrogram time-frequency distributions. Later, the signal time-frequency representation from spectrogram is considered an image, and processed through a 2-dimensional Fourier Transform in order to perform the spatial Fourier analysis from it. Finally features related with emotions in voiced speech are extracted and presented.

  10. Quantitative analysis of voice quality after radiation therapy for stage T1a glottic carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Joon Kyoo; Chung, Woong Gi [Chonnam National University Hospital, Gwangju (Korea, Republic of)

    2005-03-15

    To evaluate the voices of irradiated patients with early glottic carcinoma and to compare these with the voices of healthy volunteers. The voice samples (sustained vowel) of seventeen male patients who had been irradiated for T1a glottic squamous carcinoma at least 1 year prior to the study were analyzed with objective voice analyzer (acoustic voice analysis, aerodynamic test, and videostroboscopic analysis) and compared with those of a normal group of twenty age-and sex-matched volunteers. Average fundamental frequency, jitter, shimmer, and noise-to-harmonic ratio were obtained for acoustic voice analysis. Maximal phonation time, mean flow rate, intensity, subglottic pressure, glottal resistance, glottal efficiency, and glottal power were obtained for aerodynamic test. The irradiated group presented higher values of shimmer in acoustic voice analysis. There was no significant difference between two groups in other parameters. In this study all the objective voice parameters except shimmer were not significantly different between the irradiated group and the control group. These results suggest that the voice quality is minimally affected by radiation therapy for T1a glottic carcinoma.

  11. Voice over IP in Wireless Heterogeneous Networks

    DEFF Research Database (Denmark)

    Fathi, Hanane; Chakraborty, Shyam; Prasad, Ramjee

    The convergence of different types of traffic has preceded the convergence of systems and services in a wireless heterogeneous network. Voice and data traffic are usually treated separate in both 2G and 2.5G wireless networks. With advances in packet switching technology and especially......IP communications are difficult to achieve in a time-varying environment due to channel errors and traffic congestion and across different systems. The provision of VoIP in wireless heterogeneous networks requires a set of time-efficient control mechanisms to support a VoIP session with acceptable quality...

  12. Embodied Transcription: A Creative Method for Using Voice-Recognition Software

    Science.gov (United States)

    Brooks, Christine

    2010-01-01

    Voice-recognition software is designed to be used by one user (voice) at a time, requiring a researcher to speak all of the words of a recorded interview to achieve transcription. Thus, the researcher becomes a conduit through which interview material is inscribed as written word. Embodied Transcription acknowledges performative and interpretative…

  13. Writing from memory: history, stories and narrative voices in In The Time of The Butterflies by Julia ÁlvarezDOI:10.5007/2175-8026.2010n59p147

    Directory of Open Access Journals (Sweden)

    Manuel F Medina

    2010-03-01

    Full Text Available Julia Álvarez (Dominican Republic, 1951 and her family left the Dominican Republic in 1960 to escape the persecution of Rafael Leónidas Trujillo’s dictatorship, which ruled the country with terror from 1930 to 1961. Her father had gotten involved with clandestine forces that attempted to overthrow the dictator. Precisely the opposition to Trujillo’s dictatorship constitutes the referent of her second novel, In the Time of the Butterflies (1994, which deals with the life of the four Mirabal sisters, Minerva, María Teresa (Mate, Patria, and Dedé. My article, using a theoritical framework based mostly in the works of Foucault, Hayden White and Linda Hutcheon poses that In the Time of the Butterflies revises the official history of the Mirabal sisters and their subsequent murder by providing a more humanized version of their own stories in order to divide the truth of the myth created about the three sisters. The novel shows their development as characters as we follow them in different stages of their lives while the shadow of dictator Trujillo’s looms large encompassing every aspect of their and everybody’s existence. Lastly, I argue that Julia Álvarez’s position of being born Dominican, but acculturated as an American, allows her to observe and present the text from a unique view and perspective. She travels to the places of the facts to research the sisters’ story and to get to know the archive that includes not only the official versions, but also the most credible mythicized oral accounts provided by Dedé, the Mirabals’ other relatives, neighbors and the like. The novel’s greatest merit derives from its attempt to revise history from memory, the collective memory whose voices Álvarez masterfully reproduces and therefore perpetuates in the pages of the book.

  14. Inspiratory Phonation in Baby Voice.

    Science.gov (United States)

    Wermke, Kathleen; Haschemi, Asin Ahmad; Hesse, Volker; Robb, Michael P

    2017-05-18

    This study aimed to evaluate the developmental occurrence of inspiratory phonations (IPs) in the spontaneous cries of healthy infants across the first 10 weeks of life. This is a populational retrospective study. The spontaneous crying of 17 healthy infants (10 were male) was retrospectively investigated. Sound files of spontaneously uttered cries that were repeatedly recorded once per week for across the first 10 weeks of life were retrospectively analyzed. Frequency spectra and waveforms were used to identify the occurrence of IPs and to measure the duration and fundamental frequency (fo) of each instance of IP. A consistent number of IPs were identified across the 10-week period. All infants were observed to produce IPs in their spontaneous cries, although the frequency of occurrence was not consistent across infants. A marked sex difference was observed with female infants producing a higher number of IPs compared to males. The duration and fo of IPs did not differ significantly across the 10 weeks or between sexes. The production of IPs is a regularly occurring phenomenon in healthy, normally developing infants' spontaneous crying. The proportional difference in the production of IPs between female and male infants, observed for the first time here, is postulated to be linked to sex-based differences (including steroidal hormones) in respiratory anatomy and physiology. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  15. Mechanics of human voice production and control

    Science.gov (United States)

    Zhang, Zhaoyan

    2016-01-01

    As the primary means of communication, voice plays an important role in daily life. Voice also conveys personal information such as social status, personal traits, and the emotional state of the speaker. Mechanically, voice production involves complex fluid-structure interaction within the glottis and its control by laryngeal muscle activation. An important goal of voice research is to establish a causal theory linking voice physiology and biomechanics to how speakers use and control voice to communicate meaning and personal information. Establishing such a causal theory has important implications for clinical voice management, voice training, and many speech technology applications. This paper provides a review of voice physiology and biomechanics, the physics of vocal fold vibration and sound production, and laryngeal muscular control of the fundamental frequency of voice, vocal intensity, and voice quality. Current efforts to develop mechanical and computational models of voice production are also critically reviewed. Finally, issues and future challenges in developing a causal theory of voice production and perception are discussed. PMID:27794319

  16. Voice Outcome after Gore-Tex Medialization Thyroplasty

    Directory of Open Access Journals (Sweden)

    Elnashar, Ismail

    2015-02-01

    Full Text Available Introduction Although medialization thyroplasty utilizing Gore-Tex (Gore and Associates, Newark, Delaware, United States has been discussed in the literature, few reports have assessed voice quality afterward, and they did not use a full assessment protocol. Objective To assess the improvement in voice quality after medialization thyroplasty utilizing Gore-Tex in patients with glottic insufficiency of variable etiology. Methods Eleven patients with glottic insufficiency of different etiologies that failed compensation were operated by type 1 thyroplasty utilizing Gore-Tex. Pre- and postoperative (1 week, 3 months, and 6 months voice assessment was done and statistical analysis was performed on the results. Results In all postoperative assessments, there was significant improvement in the grade of dysphonia (p < 0.004 and highly significant reduction in the size of glottic gap and prolongation of maximum phonation time (p < 0.0001. The difference in voice parameters in the early (1 week and the late (3 and 6 months postoperative period was not significant. None of the patients developed stridor or shortness of breath necessitating tracheotomy, and there was no implant extrusion in any patient during the study period. Conclusion Gore-Tex medialization provides reliable results for both subjective and objective voice parameters. It leads to a satisfactory restoration of voice whatever the etiology of glottic incompetence is. This technique is relatively easy and does not lead to major complications. Further studies with larger number of patients and more extended periods of follow-up are still required to assess the long-term results of the technique regarding voice quality and implant extrusion.

  17. Translating Neurocognitive Models of Auditory-Verbal Hallucinations into Therapy: Using Real-time fMRI-Neurofeedback to Treat Voices

    Science.gov (United States)

    Fovet, Thomas; Orlov, Natasza; Dyck, Miriam; Allen, Paul; Mathiak, Klaus; Jardri, Renaud

    2016-01-01

    Auditory-verbal hallucinations (AVHs) are frequent and disabling symptoms, which can be refractory to conventional psychopharmacological treatment in more than 25% of the cases. Recent advances in brain imaging allow for a better understanding of the neural underpinnings of AVHs. These findings strengthened transdiagnostic neurocognitive models that characterize these frequent and disabling experiences. At the same time, technical improvements in real-time functional magnetic resonance imaging (fMRI) enabled the development of innovative and non-invasive methods with the potential to relieve psychiatric symptoms, such as fMRI-based neurofeedback (fMRI-NF). During fMRI-NF, brain activity is measured and fed back in real time to the participant in order to help subjects to progressively achieve voluntary control over their own neural activity. Precisely defining the target brain area/network(s) appears critical in fMRI-NF protocols. After reviewing the available neurocognitive models for AVHs, we elaborate on how recent findings in the field may help to develop strong a priori strategies for fMRI-NF target localization. The first approach relies on imaging-based “trait markers” (i.e., persistent traits or vulnerability markers that can also be detected in the presymptomatic and remitted phases of AVHs). The goal of such strategies is to target areas that show aberrant activations during AVHs or are known to be involved in compensatory activation (or resilience processes). Brain regions, from which the NF signal is derived, can be based on structural MRI and neurocognitive knowledge, or functional MRI information collected during specific cognitive tasks. Because hallucinations are acute and intrusive symptoms, a second strategy focuses more on “state markers.” In this case, the signal of interest relies on fMRI capture of the neural networks exhibiting increased activity during AVHs occurrences, by means of multivariate pattern recognition methods. The fine

  18. Increase in voice level and speaker comfort in lecture rooms

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Gade, Anders Christian; Bellester, Gaspar Payá

    2009-01-01

    Teachers often suffer from health problems related to their voice. These problems are related to their working environment, including the acoustics of the lecture rooms. However, there is a lack of studies linking the room acoustic parameters to the voice produced by the speaker. In this pilot...... study, the main goals are to investigate whether objectively measurable parameters of the rooms can be related to an increase in the voice sound power produced by speakers and to the speakers’ subjective judgments about the rooms. In six different rooms with different sizes, reverberation times......, and other physical attributes, the sound power level produced by six speakers was measured. Objective room acoustic parameters were measured in the same rooms, including reverberation time and room gain, and questionnaires were handed out to people who had experience talking in the rooms. It is found...

  19. 麻黄碱对非去极化肌松药起效时间的影响%The effects of ephedrine on the onset time of non-depolarizing muscular relaxant

    Institute of Scientific and Technical Information of China (English)

    任志强; 钱燕宁

    2014-01-01

    背景 麻黄碱作为一种拟交感神经药,可通过增加心输出量加速非去极化肌松药到达神经肌肉接头的速度,进而缩短肌松药的起效时间. 目的 回顾麻黄碱在缩短非去极化肌松药起效时间方面的临床应用进展,为临床麻醉提供参考. 内容 主要对麻黄碱的作用机制、给药剂量、给药时机、副作用等方面予以阐述. 趋向 麻黄碱为临床麻醉中缩短非去极化肌松药的起效时间提供一种实用的方法.%Background Ephedrine,as a kind of sympathomimetic agent,can accelerate the delivery of non-depolarizing muscle relaxant to the neuromuscular junction by increasing cardiac output,thus shortening the onset time of muscle relaxant.Objective To review the advances of ephedrine use in shortening the onset time of non-depolarizing muscle relaxant and provide reference for clinical anesthesia.Content This article mainly elaborates the mechanism of ephedrine on shortening the onset time of non-depolarizing muscle relaxant,dosage,medication timing and adverse reactions.Trend Ephedrine has been proved to provide a practical way for shortening the onset time of non-depolarizing muscle relaxant in clinical anesthesia.

  20. Onset Time of 2% Lidocaine and 0.5% Bupivacaine Mixture versus 0.5% Bupivacaine Alone using Ultrasound and Double Nerve Stimulation for Infraclavicular Brachial Plexus Anesthesia in ESRD Patients Undergoing Arteriovenous Fistula Creation.

    Science.gov (United States)

    Pongraweewan, Orawan; Inchua, Nipa; Kitsiripant, Chanatthee; Kongmuang, Benchawan; Tiwirach, Wannapa

    2016-05-01

    To reduce the onset of 0.5% bupivacaine by adding 2% lidocaine with 0.5% bupivacaine for ultrasound-guided and double stimulation technique at musculocutaneous and radial nerve for infraclavicular brachial plexus block. Prospective randomized double-blinded, controlled trial study. 90 patients undergoing creation of arteriovenous fistula under ultrasound-guided infraclavicular brachial plexus block were randomized into 2 groups. Gr B (46 patients) received 0.5% bupivacaine 30 mL and Gr BL (44 patients) received mixture of 0.5% bupivacaine 20 mL and 2% lidocaine 10 mL. The onset of sensory block were assessed by response to pinprick (grading: 0 = no sensation, 1 = hypoesthesia, and 2 = normal sensation). Rescue analgesia during the operation, duration of sensory and motor blockade were recorded. Surgeon and patient satisfactions are also evaluated using 6-point scale (0 = dissatisfied to 5 = very satisfied). There were no significant difference in the onset time of either group. Duration of sensory and motor block was not different. Surgeons' and patients' satisfaction were also not significantly different between the groups. Mixing 2% lidocaine with 0.5% bupivacaine to the final concentration of 0.67%for lidocaine and 0.33% for bupivacaine does not reduce the onset of ultrasound-guided infraclavicular brachial plexus block.

  1. Native voice, self-concept and the moral case for personalized voice technology.

    Science.gov (United States)

    Nathanson, Esther

    2017-01-01

    Purpose (1) To explore the role of native voice and effects of voice loss on self-concept and identity, and survey the state of assistive voice technology; (2) to establish the moral case for developing personalized voice technology. Methods This narrative review examines published literature on the human significance of voice, the impact of voice loss on self-concept and identity, and the strengths and limitations of current voice technology. Based on the impact of voice loss on self and identity, and voice technology limitations, the moral case for personalized voice technology is developed. Results Given the richness of information conveyed by voice, loss of voice constrains expression of the self, but the full impact is poorly understood. Augmentative and alternative communication (AAC) devices facilitate communication but, despite advances in this field, voice output cannot yet express the unique nuances of individual voice. The ethical principles of autonomy, beneficence and equality of opportunity establish the moral responsibility to invest in accessible, cost-effective, personalized voice technology. Conclusions Although further research is needed to elucidate the full effects of voice loss on self-concept, identity and social functioning, current understanding of the profoundly negative impact of voice loss establishes the moral case for developing personalized voice technology. Implications for Rehabilitation Rehabilitation of voice-disordered patients should facilitate self-expression, interpersonal connectedness and social/occupational participation. Proactive questioning about the psychological and social experiences of patients with voice loss is a valuable entry point for rehabilitation planning. Personalized voice technology would enhance sense of self, communicative participation and autonomy and promote shared healthcare decision-making. Further research is needed to identify the best strategies to preserve and strengthen identity and sense of

  2. Children's Voice or Children's Voices? How Educational Research Can Be at the Heart of Schooling

    Science.gov (United States)

    Stern, Julian

    2015-01-01

    There are problems with considering children and young people in schools as quite separate individuals, and with considering them as members of a single collectivity. The tension is represented in the use of "voice" and "voices" in educational debates. Voices in dialogue, in contrast to "children's voice", are…

  3. Voice complaints, risk factors for voice problems and history of voice problems in relation to puberty in female student teachers.

    NARCIS (Netherlands)

    Thomas, G.; Jong, F.I.C.R.S. de; Kooijman, P.G.C.; Donders, A.R.T.; Cremers, C.W.R.J.

    2006-01-01

    The aim of the study was to estimate voice complaints, risk factors for voice complaints and history of voice problems in student teachers before they embarked on their professional teaching career. A cross-sectional questionnaire survey was performed among female student teachers. The response rate

  4. Voice complaints, risk factors for voice problems and history of voice problems in relation to puberty in female student teachers.

    NARCIS (Netherlands)

    Thomas, G.; Jong, F.I.C.R.S. de; Kooijman, P.G.C.; Donders, A.R.T.; Cremers, C.W.R.J.

    2006-01-01

    The aim of the study was to estimate voice complaints, risk factors for voice complaints and history of voice problems in student teachers before they embarked on their professional teaching career. A cross-sectional questionnaire survey was performed among female student teachers. The response rate

  5. Human voice recognition depends on language ability.

    Science.gov (United States)

    Perrachione, Tyler K; Del Tufo, Stephanie N; Gabrieli, John D E

    2011-07-29

    The ability to recognize people by their voice is an important social behavior. Individuals differ in how they pronounce words, and listeners may take advantage of language-specific knowledge of speech phonology to facilitate recognizing voices. Impaired phonological processing is characteristic of dyslexia and thought to be a basis for difficulty in learning to read. We tested voice-recognition abilities of dyslexic and control listeners for voices speaking listeners' native language or an unfamiliar language. Individuals with dyslexia exhibited impaired voice-recognition abilities compared with controls only for voices speaking their native language. These results demonstrate the importance of linguistic representations for voice recognition. Humans appear to identify voices by making comparisons between talkers' pronunciations of words and listeners' stored abstract representations of the sounds in those words.

  6. Quick Statistics about Voice, Speech, and Language

    Science.gov (United States)

    ... here Home » Health Info » Statistics and Epidemiology Quick Statistics About Voice, Speech, Language Voice, Speech, Language, and ... no 205. Hyattsville, MD: National Center for Health Statistics. 2015. Hoffman HJ, Li C-M, Losonczy K, ...

  7. Introduction: Textual and contextual voices of translation

    DEFF Research Database (Denmark)

    2017-01-01

    Voices – marks of the tangle of subjectivities involved in textual processes – constitute the very fabric of texts in general and translations in particular. The title of this book, Textual and Contextual Voices of Translation, refers both to textual voices, that is, the voices found within...... the translated texts, and to contextual voices, that is, the voices of those involved in shaping, commenting, or otherwise influencing the textual voices. The latter appear in prefaces, reviews, and other texts that surround the translated texts and provide them with a context. Our main claim is that studying...... both the textual and contextual voices helps us better understand and explain the complexity of both the translation process and the translation product. The dovetailed approach to translation research that is advocated in this book aims at highlighting the diversity of participants, power positions...

  8. Self-Analysis Skills for the Developing Singer: Voice Students Who Can Analyze Their Own Singing Will Make Better Use of Their Practice Time and Become More Skilled, Expressive Singers

    Science.gov (United States)

    Barefield, Robert

    2006-01-01

    Self-analysis is a basic component of artistic development. For the singer, self-analysis is equally important, but the steps for improvement may be less visible. As Richard Alderson has noted, a singer "hears his voice from the inside through the bony structure of the head rather than outside through the eardrum. We as singers are doomed to a…

  9. Speaker's voice as a memory cue.

    Science.gov (United States)

    Campeanu, Sandra; Craik, Fergus I M; Alain, Claude

    2015-02-01

    Speaker's voice occupies a central role as the cornerstone of auditory social interaction. Here, we review the evidence suggesting that speaker's voice constitutes an integral context cue in auditory memory. Investigation into the nature of voice representation as a memory cue is essential to understanding auditory memory and the neural correlates which underlie it. Evidence from behavioral and electrophysiological studies suggest that while specific voice reinstatement (i.e., same speaker) often appears to facilitate word memory even without attention to voice at study, the presence of a partial benefit of similar voices between study and test is less clear. In terms of explicit memory experiments utilizing unfamiliar voices, encoding methods appear to play a pivotal role. Voice congruency effects have been found when voice is specifically attended at study (i.e., when relatively shallow, perceptual encoding takes place). These behavioral findings coincide with neural indices of memory performance such as the parietal old/new recollection effect and the late right frontal effect. The former distinguishes between correctly identified old words and correctly identified new words, and reflects voice congruency only when voice is attended at study. Characterization of the latter likely depends upon voice memory, rather than word memory. There is also evidence to suggest that voice effects can be found in implicit memory paradigms. However, the presence of voice effects appears to depend greatly on the task employed. Using a word identification task, perceptual similarity between study and test conditions is, like for explicit memory tests, crucial. In addition, the type of noise employed appears to have a differential effect. While voice effects have been observed when white noise is used at both study and test, using multi-talker babble does not confer the same results. In terms of neuroimaging research modulations, characterization of an implicit memory effect

  10. Surgical voice restoration after total laryngectomy: An overview

    Directory of Open Access Journals (Sweden)

    B Elmiyeh

    2010-01-01

    Full Text Available Total laryngectomy is potentially a debilitative surgery resulting in compromise of some of the most basic functions of life including speech and swallowing. This may have a profound adverse effect on the patient′s physical, functional, and emotional health, and may result in a decreased quality of life (QOL. Until the 1980s, total laryngectomy was regarded as a dreadful, but often, life-saving procedure for which there was little alternative, and was used as a last resort. At that time survival at any cost in terms of QOL was paramount and many laryngectomies were forced into an isolated life as a mute and dysphasic recluse. Most attempts at voice restoration produced inconsistent results and often techniques were laborious, expensive, and ineffective, particularly when carried out as a salvage procedure after failed radiotherapy. Progress in voice rehabilitation, following total laryngectomy, over the last 30 years, has made an enormous difference in the whole concept of the management of laryngeal cancers. Currently there are several options available for these patients, namely, esophageal speech, artificial larynx, and tracheoesophageal speech. The choice of speech rehabilitation varies from patient to patient, but tracheoesophageal voice has become the preferred method. This article provides a brief account of surgical voice restoration after total laryngectomy. Special emphasis has been given to the surgical technique, special considerations, complications, and the prevention / treatment of tracheoesophageal voice restoration.

  11. Effects of hearing loss on the voice in children.

    Science.gov (United States)

    Bolfan-Stosic, Natalija; Simunjak, Boris

    2007-04-01

    The object of this paper is to report on preliminary acoustic characteristics obtained from a group of 10 to 12 year old males from special institution from Zagreb with more than mild sensorineural hearing losses. The study was structured as an investigation of voice and resonance characteristics of Croatian children with and without sensorineural hearing loss, using sustained phonation of the vowel /a/ which was recorded using a high-quality tape recorder carried out by two voice clinicians. The samples were digitized and analyzed for frequency and spectral characteristics by EZVoice and Bruel & Kjaer Real-time Frequency Analyzer and high quality sound level meter (mouth-to-microphone distance = 30 cm). Differences were observed in perturbation measures; F0 variability; vocal intensity. Spectral deviations were also observed. Discussion focuses on application of these findings by Croatian speech and hearing specialists with the hearing impaired population. Results indicated the following: measures of jitter were significantly elevated in the hearing loss group as compared to the normal controls. A similar result was observed for measures of shimmer. Lack of voice professional's awareness of importance for making pleasant voice quality of hearing-impaired individuals was the initial idea of this study. Patients with hearing losses have been reported to show a wide variety of voice disturbances.

  12. Groningen prosthesis for voice rehabilitation after laryngectomy.

    Science.gov (United States)

    Annyas, A A; Nijdam, H F; Escajadillo, J R; Mahieu, H F; Leever, H

    1984-02-01

    Singer and Blom's endoscopic technique, using a single valved silicone prosthesis, constituted a dramatic advance in speech rehabilitation following total laryngectomy. Since 1980, we have developed a silicone biflanged prosthesis that overcomes some of the inconveniences of previous prostheses. Insertion via the mouth and the oesophagus, or as a primary procedure during total laryngectomy is easily done with the use of specially developed instruments. The success rate in 36 patients in which the voice button was inserted at the time of total laryngectomy was 86.2%.

  13. Transferring Voice using SMS over GSM Network

    CERN Document Server

    Khan, Muhammad Fahad

    2011-01-01

    The paper presents a methodology of transmitting voice in SMS (Short Message Service) over GSM network. Usually SMS contents are text based and limited to 140 bytes. It supports national and international roaming, but also supported by other telecommunication such as TDMA (Time Division Multiple Access), CDMA (Code Division Multiple Access) as well. It can sent/ receive simultaneously with other services. Such features make it favorable for this methodology. For this an application is developed using J2ME platform which is supported by all mobile phones in the world. This algorithm's test is conducted on N95 having Symbian Operating System (OS).

  14. Voicing Consciousness: The Mind in Writing

    Science.gov (United States)

    Luce-Kapler, Rebecca; Catlin, Susan; Sumara, Dennis; Kocher, Philomene

    2011-01-01

    In this paper, the authors investigate the enduring power of voice as a concept in writing pedagogy. They argue that one can benefit from considering Elbow's assertion that both text and voice be considered as important aspects of written discourse. In particular, voice is a powerful metaphor for the material, social and historical nature of…

  15. Understanding the 'Anorexic Voice' in Anorexia Nervosa.

    Science.gov (United States)

    Pugh, Matthew; Waller, Glenn

    2016-07-20

    In common with individuals experiencing a number of disorders, people with anorexia nervosa report experiencing an internal 'voice'. The anorexic voice comments on the individual's eating, weight and shape and instructs the individual to restrict or compensate. However, the core characteristics of the anorexic voice are not known. This study aimed to develop a parsimonious model of the voice characteristics that are related to key features of eating disorder pathology and to determine whether patients with anorexia nervosa fall into groups with different voice experiences. The participants were 49 women with full diagnoses of anorexia nervosa. Each completed validated measures of the power and nature of their voice experience and of their responses to the voice. Different voice characteristics were associated with current body mass index, duration of disorder and eating cognitions. Two subgroups emerged, with 'weaker' and 'stronger' voice experiences. Those with stronger voices were characterized by having more negative eating attitudes, more severe compensatory behaviours, a longer duration of illness and a greater likelihood of having the binge-purge subtype of anorexia nervosa. The findings indicate that the anorexic voice is an important element of the psychopathology of anorexia nervosa. Addressing the anorexic voice might be helpful in enhancing outcomes of treatments for anorexia nervosa, but that conclusion might apply only to patients with more severe eating psychopathology. Copyright © 2016 John Wiley & Sons, Ltd.

  16. Voice and culture: A prospect theory approach

    NARCIS (Netherlands)

    Paddock, E.L.; Ko, Junsu; Cropanzano, R.; Bagger, J.; El Akremi, A.; Camerman, A.; Greguras, G. J.; Mladinic, A.; Moliner, C.; Nam, K.; Törnblom, K.; Van den Bos, Kees

    2015-01-01

    The present study examines the congruence of individuals' minimum preferred amounts of voice with the prospect theory value function across nine countries. Accounting for previously ignored minimum preferred amounts of voice and actual voice amounts integral to testing the steepness of gain and loss

  17. Finding Voice: Learning about Language and Power

    Science.gov (United States)

    Christensen, Linda

    2011-01-01

    Christensen discusses why teachers need to teach students "voice" in its social and political context, to show the intersection of voice and power, to encourage students to ask, "Whose voices get heard? Whose are marginalized?" As Christensen writes, "Once students begin to understand that Standard English is one language among many, we can help…

  18. Analyzing the mediated voice - a datasession

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    Broadcasted voices are technologically manipulated. In order to achieve a certain autencity or sound of “reality” paradoxically the voices are filtered and trained in order to reach the listeners. This “mis-en-scene” is important knowledge when it comes to the development of a consistent method o...... of analysis of the mediated voice...

  19. Analyzing the mediated voice - a datasession

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    Broadcasted voices are technologically manipulated. In order to achieve a certain autencity or sound of “reality” paradoxically the voices are filtered and trained in order to reach the listeners. This “mis-en-scene” is important knowledge when it comes to the development of a consistent method...... of analysis of the mediated voice...

  20. Voice and culture: A prospect theory approach

    NARCIS (Netherlands)

    Paddock, E.L.; Ko, Junsu; Cropanzano, R.; Bagger, J.; El Akremi, A.; Camerman, A.; Greguras, G. J.; Mladinic, A.; Moliner, C.; Nam, K.; Törnblom, K.; Van den Bos, Kees

    2015-01-01

    The present study examines the congruence of individuals' minimum preferred amounts of voice with the prospect theory value function across nine countries. Accounting for previously ignored minimum preferred amounts of voice and actual voice amounts integral to testing the steepness of gain and loss

  1. "Voice Forum" The Human Voice as Primary Instrument in Music Therapy

    DEFF Research Database (Denmark)

    Pedersen, Inge Nygaard; Storm, Sanne

    2009-01-01

    Aspects will be drawn on the human voice as tool for embodying our psychological and physiological state, and attempting integration of feelings. Presentations and dialogues on different methods and techniques in "Therapy related body-and voice work.", as well as the human voice as a tool for non...... for nonverbal orientation and information both to our selves and others. Focus on training on the voice instrument, the effect and impact of the human voice, and listening perspectives...

  2. Voice-Specialized Speech-Language Pathologist's Criteria for Discharge from Voice Therapy.

    Science.gov (United States)

    Gillespie, Amanda I; Gartner-Schmidt, Jackie

    2017-08-07

    No standard protocol exists to determine when a patient is ready and able to be discharged from voice therapy. The aim of the present study was to determine what factors speech-language pathologists (SLPs) deem most important when discharging a patient from voice therapy. A second aim was to determine if responses differed based on years of voice experience. Step 1: Seven voice-specialized SLPs generated a list of items thought to be relevant to voice therapy discharge. Step 2: Fifty voice-specialized SLPs rated each item on the list in terms of importance in determining discharge from voice therapy. Step 1: Four themes emerged-outcome measures, laryngeal appearance, SLP perceptions, and patient factors-as important items when determining discharge from voice therapy. Step 2: The top five most important criteria for discharge readiness were that the patient had to be able to (1) independently use a better voice (transfer), (2) function with his or her new voice production in activities of daily living (transfer), (3) differentiate between good and bad voice, (4) take responsibility for voice, and (5) sound better from baseline. Novice and experienced clinicians agreed between 94% and 97% concerning what was deemed "very important." SLPs agree that a patient's ability to use voice techniques in conversation and real-life situations outside of the therapy room are the most important determinants for voice therapy discharge. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  3. Increase in voice level and speaker comfort in lecture rooms

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Gade, Anders Christian; Bellester, Gaspar Payá

    2009-01-01

    Teachers often suffer from health problems related to their voice. These problems are related to their working environment, including the acoustics of the lecture rooms. However, there is a lack of studies linking the room acoustic parameters to the voice produced by the speaker. In this pilot......, and other physical attributes, the sound power level produced by six speakers was measured. Objective room acoustic parameters were measured in the same rooms, including reverberation time and room gain, and questionnaires were handed out to people who had experience talking in the rooms. It is found...

  4. 声带显微手术后发声功能恢复和嗓音训练时间的初步探讨%Preliminary Study on Functional Recovery and Voice Training Time after Microsurgical Operation of Vocal Cords

    Institute of Scientific and Technical Information of China (English)

    陈志鹏; 熊姗姗; 李美丽; 彭伟; 李文生; 沈康

    2015-01-01

    Objective:To discuss the recovery of function and voice training time after microsurgical operation of vocal cords.Method:152 vocal cord polyps patients with vocal cord microsurgery from January 2011 to April 2014 in institute of otolaryngology department as research objects,using the voice acoustic analysis,compared to the voice acoustic parametersduring preoperative and postoperative 3,5,7 days.In accordance with the draw random sampling method 152 patients were divided into two groups,patients in group A at 1 weeks after surgery to give voice training,patients in group B at 2 weeks after surgery to give voice training.6 months after voice training,to compare the voice acoustic parameters,VHI scores and GRBAS scores of the two groups.Result:3 d after the operation,the acoustic parameters in patients decreased,had no significant difference compared with that before operation,from 5 d after operation,the acoustic parameters significantly decreased compared with that before operation,there were differences in statistical significance (P<0.05).Before voice training, two groups of patients with voice acoustic parameters,VHI scores and GRBAS scores had no significance,6 months after voice training,two groups of patients with voice acoustic parameters,VHI scores and GRBAS scores were significantly improved, group B improved more significantly than group A (P<0.05).Conclusion:The voice quality begin to restore 5 d after surgery in patients with vocal cord polyp microstructure,but patients within 2 weeks after a rigorous hugh rear can make voice training.%目的:探讨声带显微手术后发声功能恢复和嗓音训练时间。方法:选取2011年1月-2014年4月本院耳鼻咽喉科收治的152例行声带显微手术的声带息肉患者为研究对象,采用嗓音声学分析,对其术前、术后3、5、7 d,各嗓音声学参数进行比较。按照抽签随机取样法将152例患者均分为两组,A组患者于手术后1周给予嗓音

  5. A Timely Voice: Garth Boomer on Literature

    Science.gov (United States)

    Sawyer, Wayne

    2013-01-01

    In the conceptual triumvirate of "language," "literacy" and "literature" that have been central to thinking about English curriculum--indeed, are the overarching organisers for the "Australian Curriculum: English"--that which received possibly the least attention from Garth Boomer was literature. This paper…

  6. Does a pneumotach accurately characterize voice function?

    Science.gov (United States)

    Walters, Gage; Krane, Michael

    2016-11-01

    A study is presented which addresses how a pneumotach might adversely affect clinical measurements of voice function. A pneumotach is a device, typically a mask, worn over the mouth, in order to measure time-varying glottal volume flow. By measuring the time-varying difference in pressure across a known aerodynamic resistance element in the mask, the glottal volume flow waveform is estimated. Because it adds aerodynamic resistance to the vocal system, there is some concern that using a pneumotach may not accurately portray the behavior of the voice. To test this hypothesis, experiments were performed in a simplified airway model with the principal dimensions of an adult human upper airway. A compliant constriction, fabricated from silicone rubber, modeled the vocal folds. Variations of transglottal pressure, time-averaged volume flow, model vocal fold vibration amplitude, and radiated sound with subglottal pressure were performed, with and without the pneumotach in place, and differences noted. Acknowledge support of NIH Grant 2R01DC005642-10A1.

  7. The development of the Spanish verb ir into auxiliary of voice

    DEFF Research Database (Denmark)

    Vinther, Thora

    2005-01-01

    spanish, syntax, grammaticalisation, past participle, passive voice, middle voice, language development......spanish, syntax, grammaticalisation, past participle, passive voice, middle voice, language development...

  8. Efficacy of conservative voice treatment in male-to-female transsexuals.

    Science.gov (United States)

    Mészáros, Krisztina; Vitéz, Lajos Csokonai; Szabolcs, István; Góth, Miklós; Kovács, László; Görömbei, Zoltán; Hacki, Tamás

    2005-01-01

    A voice assessment was performed before and after conservative voice treatment in 3 male-to-female transsexuals and in 2 nontreated transsexuals serving as control persons. The characteristics studied were voice quality, habitual speaking pitch, vocal pitch range, vocal intensity range, maximum phonation time and 'communicative impairment', a subjective self-estimation by the patient. Based on these parameters the Friedrich dysphonia index (DI) was calculated. The habitual speaking pitch of the 3 transsexuals who had received voice treatment became female, in contrast to that of the nontreated transsexuals, which remained in the so-called 'indifferent pitch range'. The DI of the treated patients was close to the normal value, in contrast to the DI of controls, which continued to be pathological. Even based on this small population, study results reflected the effectiveness of voice therapy in transsexuals.

  9. Differential labour market impacts from disability onset.

    Science.gov (United States)

    Polidano, Cain; Vu, Ha

    2015-03-01

    We estimate the causal labour market impacts of disability onset by gender, age and education levels up to 4 years after onset using longitudinal data from the Household Income and Labour Dynamics Australia survey and difference-in-difference propensity score matching techniques. We find lasting negative impacts on employment, especially full-time employment, which is due more to reduced movement into full-time employment than downshifting from full-time to part-time work following onset. Those without post-school education qualifications are particularly vulnerable to the impacts of onset and are more likely to be out of work and on income support than those with qualifications up to 4 years after onset, due in part because they have greater difficulty adjusting.

  10. Who gets credit for input? Demographic and structural status cues in voice recognition.

    Science.gov (United States)

    Howell, Taeya M; Harrison, David A; Burris, Ethan R; Detert, James R

    2015-11-01

    The authors investigate the employee features that, alongside overall voice expression, affect supervisors' voice recognition. Drawing primarily from status characteristics and network position theories, the authors propose and find in a study of 693 employees from 89 different credit union units that supervisors are more likely to credit those reporting the same amount of voice if the employees have higher ascribed or assigned (by the organization) status--cued by demographic variables such as majority ethnicity and full-time work hours. Further, supervisors are more likely to recognize voice from employees who have higher achieved status--cued by their centrality in informal social structures. The authors also find that even when certain groups of lower status employees speak up more, they cannot compensate for the negative effect of their demographic membership on voice recognition by their boss. The authors underscore how recognition of employee voice by supervisors matters for employees. It carries (mediates) the effects of voice expression and status onto performance evaluations 1 year later, which means that demographic differences in the assignment of credit for voice can serve as an implicit pathway for discrimination.

  11. Use of loud phonation as a voice therapy technique for children with vocal nodules

    Science.gov (United States)

    Kobayashi, Noriko; Hirose, Hajime; Nishiyama, Koichiro

    2003-10-01

    For the treatment of vocal nodules, educational programs for vocal hygiene and voice training for acquisition of correct phonation are essential. In the case of children, special considerations are necessary as some of their vocal behaviors and reaction to voice disorders are different from those of adults. In this study, a voice therapy program for child vocal nodules were developed and good results were obtained for six children. They were four boys and two girls (Age: 4-11 yr) and bilateral nodules were found for all of them. In addition to a conventional vocal hygiene program for children, correct production of loud voice (so-called gBeltingh) was the major focus of the voice therapy as the visual inspection of the larynges and perceptual evaluations of the voice revealed inappropriate loud voice production with laryngeal constriction in all children. After 5-24 voice therapy sessions, disappearance of the nodules was found in five children and the reduction of the nodule sizes was found in one child. Improvement of the GRBAS scores, longer maximum phonation time, and extension of vocal ranges were found after the completion of the therapy programs.

  12. Playful Interaction with Voice Sensing Modular Robots

    DEFF Research Database (Denmark)

    Heesche, Bjarke; MacDonald, Ewen; Fogh, Rune

    2013-01-01

    This paper describes a voice sensor, suitable for modular robotic systems, which estimates the energy and fundamental frequency, F0, of the user’s voice. Through a number of example applications and tests with children, we observe how the voice sensor facilitates playful interaction between...... children and two different robot configurations. In future work, we will investigate if such a system can motivate children to improve voice control and explore how to extend the sensor to detect emotions in the user’s voice....

  13. Voice training and changing weight--are they reflected in speaking fundamental frequency, voice range, and pitch breaks of 13-year-old girls? A longitudinal study.

    Science.gov (United States)

    Willis, Elizabeth C; Kenny, Dianna T

    2011-09-01

    Assessment of the voice-change progress of 20 girls (12-13 years) over 1 year by observing changes in speaking fundamental frequency (SFo), voice range, and register pitch breaks in the context of weight, height, voice training, and self-perception. One-year longitudinal collective case study. Twenty girls were recorded at the beginning and end of a year; nine girls were recorded another three times. SFo, vocal range, and characteristics were analyzed and interactions between these data assessed against weight and height to indicate pubertal development, and to test the hypothesis that changes in weight, height, SFo, and pitch breaks were related. Effects of training and the girls' self-perception of their voice use were also assessed. Vocal characteristics changed as the girls passed through different weight ranges. During 47.5-52.4 kg (called band 2) and 52.4-57.5 kg (band 3), there was progressive contraction of vocal range and in some girls a slight rise in SFo between recording times 1 and 5. Both high- and low-pitch breaks were present in 45% of girls' voices. Girls in band 4 (confidence; all girls lost confidence in their voice use over the year. In this longitudinal study of twenty 13-year-old girls, voice changes in SFo, vocal range, and pitch-break frequency were synchronous with certain weight ranges. Girls with training registered higher maximum phonational frequency and were more confident in their voice use than girls without training. Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  14. Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing.

    Science.gov (United States)

    Chang, Qing; Tang, Wenxue; Kim, Yeunjung; Lin, Xi

    2015-01-01

    Mutations in the Gjb2 gene, which encodes a gap junction protein connexin26 (Cx26), are the most prevalent form of hereditary deafness in humans and represent about half of non-syndromic congenital deafness cases in many ethnic populations. Cochlear potassium (K+) recycling in mature cochlea is required for normal hearing. It is thought that gap junctions are essential for K+ recycling and that Gjb2 mutations cause Gjb2-associated deafness by disrupting K+ recycling in mature cochlea. Here we present evidence showing that Gjb2 is required for normal development of the neonatal organ of Corti prior to the onset of the hearing in mice. In the conditional Gjb2 null (cCx26 null) mice, ribbon synapses in inner hair cells remained poorly developed, the afferent type I fibers failed to finish the refinement process to form convergent innervation to individual inner hair cells. The spontaneous depolarizing activities in the supporting cells, which normally diminish in the wild type cochleae after postnatal day 8 (P8), remained strong in the cochlea after P8 in the mutant mice. Furthermore, the deafness phenotype was readily generated only if the Cx26 expression in the organ of Corti was significantly reduced before P6. Similar amount of Cx26 reduction in more mature cochleae had a much weaker effect in damaging the hearing sensitivity. Our findings indicated that Cx26 plays essential roles in the maturation process of the organ of Corti prior to the establishment of high K+ in the endolymph and the onset of hearing. These results suggest that successful treatment of Cx26 deafness requires early intervention before the cochlea fully matures.

  15. Voices from the Classroom: Educational Practice Can Inform Policy.

    Science.gov (United States)

    Flinders, David J.

    Educational policy discussions typically exclude the teacher's voice and ignore constraints of time, energy, and resources that challenge teachers and hinder policy implementation. The case studies presented in this monograph attempt to restore the teacher's perspective. Rather than analyzing policy shortfalls stemming from teacher "apathy" or…

  16. The effect of voice rest on the outcome of phonosurgery for benign laryngeal lesions: preliminary results of a prospective randomized study.

    Science.gov (United States)

    Kiagiadaki, Devora; Remacle, Marc; Lawson, George; Bachy, Vincent; Van der Vorst, Sebastien

    2015-05-01

    According to the literature, voice rest following phonosurgery, as recommended in clinical practice, varies between 3 and 7 days. However, up until now, no randomized trials have been published comparing voice rest of short versus long duration. This is an ongoing prospective randomized study, comparing strict voice rest of 5 versus 10 days on the voice following phonosurgery. Thirty-one elective patients operated on for benign laryngeal lesions were randomized. They completed pre- and postoperative assessments, including perceptual voice quality (Grade, Roughness, Breathiness, Asthenia, Strain, Instability scale), Voice Handicap Index total score, and voice analysis with both acoustic and aerodynamic measurements. Additional factors such as smoking, vocal abuse, reflux, and preoperative speech therapy were also taken into account. Sixteen patients were randomized to follow 5 days' voice rest and 15 patients were randomized to 10 days' voice rest. Statistical analysis showed no significant differences in pre- or postoperative measurements between the 2 groups. However, multilinear regression analysis for the effect of voice rest duration on postoperative values showed a significant improvement in maximum phonation time (MPT) with 10 days' voice rest. Preliminary results show a benefit of prolonged voice rest (10 days' duration) on MPT. © The Author(s) 2014.

  17. VOICE QUALITY BEFORE AND AFTER THYROIDECTOMY

    Directory of Open Access Journals (Sweden)

    Dora CVELBAR

    2016-04-01

    Full Text Available Introduction: Voice disorders are a well-known complication which is often associated with thyroid gland diseases and because voice is still the basic mean of communication it is very important to maintain its quality healthy. Objectives: The aim of this study referred to questions whether there is a statistically significant difference between results of voice self-assessment, perceptual voice assessment and acoustic voice analysis before and after thyroidectomy and whether there are statistically significant correlations between variables of voice self-assessment, perceptual assessment and acoustic analysis before and after thyroidectomy. Methods: This scientific research included 12 participants aged between 41 and 76. Voice self-assessment was conducted with the help of Croatian version of Voice Handicap Index (VHI. Recorded reading samples were used for perceptual assessment and later evaluated by two clinical speech and language therapists. Recorded samples of phonation were used for acoustic analysis which was conducted with the help of acoustic program Praat. All of the data was processed through descriptive statistics and nonparametric statistical methods. Results: Results showed that there are statistically significant differences between results of voice self-assessments and results of acoustic analysis before and after thyroidectomy. Statistically significant correlations were found between variables of perceptual assessment and acoustic analysis. Conclusion: Obtained results indicate the importance of multidimensional, preoperative and postoperative assessment. This kind of assessment allows the clinician to describe all of the voice features and provides appropriate recommendation for further rehabilitation to the patient in order to optimize voice outcomes.

  18. Beyond Insularity: Releasing the Voices.

    Science.gov (United States)

    Greene, Maxine

    1993-01-01

    Aspects of English-as-a-Second-Language are discussed from the standpoint of a teacher-educator with a particular interest in philosophy, the arts, and humanities and what they signify for the schools. The idea of giving voice to all viewpoints and sociocultural circumstances is considered for content learning and heterogeneous grouping. (Contains…

  19. A voice and nothing more

    DEFF Research Database (Denmark)

    Mebus, Andreas Nozic Lindgren

    2012-01-01

    Andreas Mebus fokuserer herefter på et helt konkret aspekt af talen, nemlig ”stemmen” i sin artikel ”A voice and nothing more – en filosofisk udredning af stemmen”. Gennem Mladen Dolars teori om stemmen, redegør Mebus for de forskellige aspekter ved stemmen; som bærer af mening, som æstetisk...

  20. Voice, Citizenship, and Civic Action

    DEFF Research Database (Denmark)

    Tufte, Thomas

    2014-01-01

    In recent years the world has experienced a resurgence in practices of bottom-up communication for social change, a plethora of agency in which claims for voice and citizenship through massive civic action have conquered center stage in the public debate. This resurgence has sparked a series...

  1. FILTWAM and Voice Emotion Recognition

    NARCIS (Netherlands)

    Bahreini, Kiavash; Nadolski, Rob; Westera, Wim

    2014-01-01

    This paper introduces the voice emotion recognition part of our framework for improving learning through webcams and microphones (FILTWAM). This framework enables multimodal emotion recognition of learners during game-based learning. The main goal of this study is to validate the use of microphone d

  2. The Performing Voice of Radio

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    The ongoing international development of opening media archives for researchers as well as for broader audiences calls for a closer discussion of the mediated voice and how to analyse it. Which parameters can be analysed and which parameters are not covered by the analysis? Furthermore, how do we...

  3. Voice and choice by delegation

    NARCIS (Netherlands)

    van de Bovenkamp, H.; Vollaard, H.; Trappenburg, M.; Grit, K

    2013-01-01

    In many Western countries, options for citizens to influence public services are increased to improve the quality of services and democratize decision making. Possibilities to influence are often cast into Albert Hirschman's taxonomy of exit (choice), voice, and loyalty. In this article we identify

  4. Work-related voice disorder

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    Paulo Eduardo Przysiezny

    2015-04-01

    Full Text Available INTRODUCTION: Dysphonia is the main symptom of the disorders of oral communication. However, voice disorders also present with other symptoms such as difficulty in maintaining the voice (asthenia, vocal fatigue, variation in habitual vocal fundamental frequency, hoarseness, lack of vocal volume and projection, loss of vocal efficiency, and weakness when speaking. There are several proposals for the etiologic classification of dysphonia: functional, organofunctional, organic, and work-related voice disorder (WRVD.OBJECTIVE: To conduct a literature review on WRVD and on the current Brazilian labor legislation.METHODS: This was a review article with bibliographical research conducted on the PubMed and Bireme databases, using the terms "work-related voice disorder", "occupational dysphonia", "dysphonia and labor legislation", and a review of labor and social security relevant laws.CONCLUSION: WRVD is a situation that frequently is listed as a reason for work absenteeism, functional rehabilitation, or for prolonged absence from work. Currently, forensic physicians have no comparative parameters to help with the analysis of vocal disorders. In certain situations WRVD may cause, work disability. This disorder may be labor-related, or be an adjuvant factor to work-related diseases.

  5. The Performing Voice of Radio

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    The ongoing international development of opening media archives for researchers as well as for broader audiences calls for a closer discussion of the mediated voice and how to analyse it. Which parameters can be analysed and which parameters are not covered by the analysis? Furthermore, how do we...

  6. Adolescent Leadership: The Female Voice

    Science.gov (United States)

    Archard, Nicole

    2013-01-01

    This research investigated the female adolescent view of leadership by giving voice to student leaders through focus group discussions. The questions: What is leadership? Where/how was leadership taught?, and How was leadership practised? were explored within the context of girls' schools located in Australia, with one school located in South…

  7. FILTWAM and Voice Emotion Recognition

    NARCIS (Netherlands)

    Bahreini, Kiavash; Nadolski, Rob; Westera, Wim

    2014-01-01

    This paper introduces the voice emotion recognition part of our framework for improving learning through webcams and microphones (FILTWAM). This framework enables multimodal emotion recognition of learners during game-based learning. The main goal of this study is to validate the use of microphone

  8. Voicing children's critique and utopias

    DEFF Research Database (Denmark)

    Husted, Mia; Lind, Unni

    2016-01-01

    , designed to accommodate children's participation through graphic illustrations of young children's critique and utopias. The study is informed by a commitment to democratic participation and processes (Reason and Bradbury 2001, Gunnarsson et al. 2016). Ethical guidelines implied dialogues and discussions......, children's voice, critique and utopias, pedagogical work...

  9. Women's Voices in Experiential Education.

    Science.gov (United States)

    Warren, Karen, Ed.

    This book is a collection of feminist analyses of various topics in experiential education, particularly as it applies to outdoors and adventure education, as well as practical examples of how women's experiences can contribute to the field as a whole. Following an introduction, "The Quilt of Women's Voices" (Maya Angelou), the 25…

  10. Temporal voice areas exist in autism spectrum disorder but are dysfunctional for voice identity recognition

    Science.gov (United States)

    Borowiak, Kamila; von Kriegstein, Katharina

    2016-01-01

    The ability to recognise the identity of others is a key requirement for successful communication. Brain regions that respond selectively to voices exist in humans from early infancy on. Currently, it is unclear whether dysfunction of these voice-sensitive regions can explain voice identity recognition impairments. Here, we used two independent functional magnetic resonance imaging studies to investigate voice processing in a population that has been reported to have no voice-sensitive regions: autism spectrum disorder (ASD). Our results refute the earlier report that individuals with ASD have no responses in voice-sensitive regions: Passive listening to vocal, compared to non-vocal, sounds elicited typical responses in voice-sensitive regions in the high-functioning ASD group and controls. In contrast, the ASD group had a dysfunction in voice-sensitive regions during voice identity but not speech recognition in the right posterior superior temporal sulcus/gyrus (STS/STG)—a region implicated in processing complex spectrotemporal voice features and unfamiliar voices. The right anterior STS/STG correlated with voice identity recognition performance in controls but not in the ASD group. The findings suggest that right STS/STG dysfunction is critical for explaining voice recognition impairments in high-functioning ASD and show that ASD is not characterised by a general lack of voice-sensitive responses. PMID:27369067

  11. The eye-voice span during reading aloud

    Directory of Open Access Journals (Sweden)

    Jochen eLaubrock

    2015-09-01

    Full Text Available Although eye movements during reading are modulated by cognitive processing demands, they also reflect visual sampling of the input, and possibly preparation of output for speech or the inner voice. By simultaneously recording eye movements and the voice during reading aloud, we obtained an output measure that constrains the length of time spent on cognitive processing. Here we investigate the dynamics of the eye-voice span (EVS, the distance between eye and voice. We show that the EVS is regulated immediately during fixation of a word by either increasing fixation duration or programming a regressive eye movement against the reading direction. EVS size at the beginning of a fixation was positively correlated with the likelihood of regressions and refixations. Regression probability was further increased if the EVS was still large at the end of a fixation: if adjustment of fixation duration did not sufficiently reduce the EVS during a fixation, then a regression rather than a refixation followed with high probability. We further show that the EVS can help understand cognitive influences on fixation duration during reading: in mixed model analyses, the EVS was a stronger predictor of fixation durations than either word frequency or word length. The EVS modulated the influence of several other predictors on single fixation durations. For example, word-N frequency effects were larger with a large EVS, especially when word N-1 frequency was low. Finally, a comparison of single fixation durations during oral and silent reading showed that reading is governed by similar principles in both reading modes, although EVS maintenance and articulatory processing also cause some differences. In summary, the eye-voice span is regulated by adjusting fixation duration and/or by programming a regressive eye movement when the eye-voice span gets too large. Overall, the EVS appears to be directly related to updating of the working memory buffer during reading.

  12. Visual assessment of voice disorders in patients with occupational dysphonia

    Directory of Open Access Journals (Sweden)

    Bożena Kosztyła-Hojna

    2014-11-01

    Full Text Available [b]introduction[/b]. In a group of persons using the voice occupationally, the frequent symptoms are hoarseness, voice fatigability and aphonia. Pathological changes in the larynx may have organic or functional character which require different methods of treatment and rehabilitation. Visualization of vibrations of the vocal folds is an essential condition for an appropriate assessment of the causes of dysphonia. [b]objective[/b]. The purpose of the study is assessment of the usefulness of a high-speed imaging (HSI system in the diagnosis of functional and organic dysphonia of occupational character, compared with digital kymography (DKG and digital stroboscopy (DS with a high resolution module. [b]material and methods[/b]. The study group consisted of 64 patients with voice quality disorders with features of occupational dysphonia. The control group consisted of 15 patients with euphonic voice. Analysis of the voice quality parameters during phonation of the ‘e’ vowel was performed using HSI, DKG and stroboscopy of high resolution, by means of a digital HS camera (HRES Endocam, Richard Wolf GmbH, Knittlingen, Germany. Vocal folds vibrations were registered at the rate of 4,000 frames per second. [b]results[/b]. HSI is the most reliable diagnostic tool giving the possibility of an analysis of the true vibrations of the vocal folds. It also enables an observation of the aperiodicity of vibrations of the vocal folds, while DS with high resolution allows diagnosis of the periodicity of the vibrations. [b]conclusions[/b]. HSI is particularly useful in the diagnosis of neurologically-based pathology of the voice (paralytic dysphonia and organic dysphonia. The quickest method of diagnosing the phonatory paresis of the glottis is DKG. The advantage of both HSI and DKG is the non-invasiveness of examinations; however, their limitations are time-consuming and the high cost of equipment.

  13. The maximum intelligible range of the human voice

    Science.gov (United States)

    Boren, Braxton

    This dissertation examines the acoustics of the spoken voice at high levels and the maximum number of people that could hear such a voice unamplified in the open air. In particular, it examines an early auditory experiment by Benjamin Franklin which sought to determine the maximum intelligible crowd for the Anglican preacher George Whitefield in the eighteenth century. Using Franklin's description of the experiment and a noise source on Front Street, the geometry and diffraction effects of such a noise source are examined to more precisely pinpoint Franklin's position when Whitefield's voice ceased to be intelligible. Based on historical maps, drawings, and prints, the geometry and material of Market Street is constructed as a computer model which is then used to construct an acoustic cone tracing model. Based on minimal values of the Speech Transmission Index (STI) at Franklin's position, Whitefield's on-axis Sound Pressure Level (SPL) at 1 m is determined, leading to estimates centering around 90 dBA. Recordings are carried out on trained actors and singers to determine their maximum time-averaged SPL at 1 m. This suggests that the greatest average SPL achievable by the human voice is 90-91 dBA, similar to the median estimates for Whitefield's voice. The sites of Whitefield's largest crowds are acoustically modeled based on historical evidence and maps. Based on Whitefield's SPL, the minimal STI value, and the crowd's background noise, this allows a prediction of the minimally intelligible area for each site. These yield maximum crowd estimates of 50,000 under ideal conditions, while crowds of 20,000 to 30,000 seem more reasonable when the crowd was reasonably quiet and Whitefield's voice was near 90 dBA.

  14. Singing voice handicap mapped by different self-assessment instruments.

    Science.gov (United States)

    Paoliello, Karla; Oliveira, Gisele; Behlau, Mara

    2013-01-01

    To map voice handicap of popular singers with a general voice and two singing voice self-assessment questionnaires. Fifty singers, 25 male and 25 female, 23 with vocal complaint and 27 without vocal complaint answered randomly the questionnaires. For the comparison of data, the following statistical tests were performed: Mann-Whitney, Friedman, Wilcoxon, Spearman and Correlation. Data showed that the VHI yielded a smaller handicap when compared to the other two questionnaires (VHI x S-VHI - p=0.001; VHI x MSVH - p=0.004). The S-VHI and MSVH produced similar results (p=0.723). Singers with vocal complaint had a VHI total score of 17.5. The other two instruments showed more deviated scores (S-VHI - 24.9; MSVH - 25.2). There was no relationship between gender and singing style with the handicap perceived. A weak negative correlation between the perceived handicap and the time of singing experience was found (-37.7 to -13.10%), that is, the smaller the time of singing experience, the greater the handicap is. The questionnaires developed for the assessment of singing voice, S-VHI and MSVH, showed to be more specific and correspondent to each other for the evaluation of vocal handicap in singers. Findings showed that the more the time of singer's singing experience, the smaller the handicap is. Gender and singing styles did not influence the perception of the handicap.

  15. The Human Voice in Speech and Singing

    Science.gov (United States)

    Lindblom, Björn; Sundberg, Johan

    This chapter speech describes various aspects of the human voice as a means of communication in speech and singing. From the point of view of function, vocal sounds can be regarded as the end result of a three stage process: (1) the compression of air in the respiratory system, which produces an exhalatory airstream, (2) the vibrating vocal folds' transformation of this air stream to an intermittent or pulsating air stream, which is a complex tone, referred to as the voice source, and (3) the filtering of this complex tone in the vocal tract resonator. The main function of the respiratory system is to generate an overpressure of air under the glottis, or a subglottal pressure. Section 16.1 describes different aspects of the respiratory system of significance to speech and singing, including lung volume ranges, subglottal pressures, and how this pressure is affected by the ever-varying recoil forces. The complex tone generated when the air stream from the lungs passes the vibrating vocal folds can be varied in at least three dimensions: fundamental frequency, amplitude and spectrum. Section 16.2 describes how these properties of the voice source are affected by the subglottal pressure, the length and stiffness of the vocal folds and how firmly the vocal folds are adducted. Section 16.3 gives an account of the vocal tract filter, how its form determines the frequencies of its resonances, and Sect. 16.4 gives an account for how these resonance frequencies or formants shape the vocal sounds by imposing spectrum peaks separated by spectrum valleys, and how the frequencies of these peaks determine vowel and voice qualities. The remaining sections of the chapter describe various aspects of the acoustic signals used for vocal communication in speech and singing. The syllable structure is discussed in Sect. 16.5, the closely related aspects of rhythmicity and timing in speech and singing is described in Sect. 16.6, and pitch and rhythm aspects in Sect. 16.7. The impressive

  16. Acoustic and perceptual characteristics of voicing in fricatives and fricative clusters.

    Science.gov (United States)

    Stevens, K N; Blumstein, S E; Glicksman, L; Burton, M; Kurowski, K

    1992-05-01

    Several types of measurements were made to determine the acoustic characteristics that distinguish between voiced and voiceless fricatives in various phonetic environments. The selection of measurements was based on a theoretical analysis that indicated the acoustic and aerodynamic attributes at the boundaries between fricatives and vowels. As expected, glottal vibration extended over a longer time in the obstruent interval for voiced fricatives than for voiceless fricatives, and there were more extensive transitions of the first formant adjacent to voiced fricatives than for the voiceless cognates. When two fricatives with different voicing were adjacent, there were substantial modifications of these acoustic attributes, particularly for the syllable-final fricative. In some cases, these modifications leads to complete assimilation of the voicing feature. Several perceptual studies with synthetic vowel-consonant-vowel stimuli and with edited natural stimuli examined the role of consonant duration, extent and location of glottal vibration, and extent of formant transitions on the identification of the voicing characteristics of fricatives. The perceptual results were in general consistent with the acoustic observations and with expectations based on the theoretical model. The results suggest that listeners base their voicing judgments of intervocalic fricatives on an assessment of the time interval in the fricative during which there is no glottal vibration. This time interval must exceed about 60 ms if the fricative is to be judged as voiceless, except that a small correction to this threshold is applied depending on the extent to which the first-formant transitions are truncated at the consonant boundaries.

  17. The simulated features of heliospheric cosmic-ray modulation with a time-dependent drift model. II - On the energy dependence of the onset of new modulation in 1987

    Science.gov (United States)

    Le Roux, J. A.; Potgieter, M. S.

    1992-01-01

    Time-dependent heliospheric cosmic-ray modulation for the period 1985-1989 is simulated by means of a time-dependent axially symmetric drift model with an emulated wavy heliospheric neutral sheet (HNS). The model is used to extend previous calculations to other energies in order to study a possible energy-dependence of the onset of new modulation at various radial distances in 1987. The model, with the outward propagating changes of the HNS as the only time-dependent parameters, is found to predict essentially no energy-dependence in the time when new modulation started in the simulated 1987. When a more practical approach in defining 'constant' modulation in 1987 is followed, the present calculations can be interpreted to indicate that the end of the recovery period in 1987 happened progressively earlier and the onset of new modulation progressively later the higher the rigidity of the cosmic rays. This period of relatively unchanged modulation is predicted to last longer with increasing radial distance.

  18. Context, Contrast, and Tone of Voice in Auditory Sarcasm Perception.

    Science.gov (United States)

    Voyer, Daniel; Thibodeau, Sophie-Hélène; Delong, Breanna J

    2016-02-01

    Four experiments were conducted to investigate the interplay between context and tone of voice in the perception of sarcasm. These experiments emphasized the role of contrast effects in sarcasm perception exclusively by means of auditory stimuli whereas most past research has relied on written material. In all experiments, a positive or negative computer-generated context spoken in a flat emotional tone was followed by a literally positive statement spoken in a sincere or sarcastic tone of voice. Participants indicated for each statement whether the intonation was sincere or sarcastic. In Experiment 1, a congruent context/tone of voice pairing (negative/sarcastic, positive/sincere) produced fast response times and proportions of sarcastic responses in the direction predicted by the tone of voice. Incongruent pairings produced mid-range proportions and slower response times. Experiment 2 introduced ambiguous contexts to determine whether a lower context/statements contrast would affect the proportion of sarcastic responses and response time. Results showed the expected findings for proportions (values between those obtained for congruent and incongruent pairings in the direction predicted by the tone of voice). However, response time failed to produce the predicted pattern, suggesting potential issues with the choice of stimuli. Experiments 3 and 4 extended the results of Experiments 1 and 2, respectively, to auditory stimuli based on written vignettes used in neuropsychological assessment. Results were exactly as predicted by contrast effects in both experiments. Taken together, the findings suggest that both context and tone influence how sarcasm is perceived while supporting the importance of contrast effects in sarcasm perception.

  19. Delayed otolaryngology referral for voice disorders increases health care costs.

    Science.gov (United States)

    Cohen, Seth M; Kim, Jaewhan; Roy, Nelson; Courey, Mark

    2015-04-01

    Despite the accepted role of laryngoscopy in assessing patients with laryngeal/voice disorders, controversy surrounds its timing. This study sought to determine how increased time from first primary care to first otolaryngology outpatient visit affected the health care costs of patients with laryngeal/voice disorders. Retrospective analysis of a large, national administrative claims database was performed. Patients had an International Classification of Diseases, 9(th) Revision-coded diagnosis of a laryngeal/voice disorder; initially saw a primary care physician and, subsequently, an otolaryngologist as outpatients; and provided 6 months of follow-up data after the first otolaryngology evaluation. The outpatient health care costs accrued from the first primary care outpatient visit through the 6 months after the first otolaryngology outpatient visit were determined. There were 260,095 unique patients who saw a primary care physician as an outpatient for a laryngeal/voice disorder, with 8999 (3.5%) subsequently seeing an otolaryngologist and with 6 months postotolaryngology follow-up data. A generalized linear regression model revealed that, compared with patients who saw an otolaryngologist ≤1 month after the first primary care visit, patients in the >1-month and ≤3-months and >3-months time periods had relative mean cost increases of $271.34 (95% confidence interval $115.95-$426.73) and $711.38 (95% confidence interval $428.43-$993.34), respectively. Increased time from first primary care to first otolaryngology evaluation is associated with increased outpatient health care costs. Earlier otolaryngology examination may reduce health care expenditures in the evaluation and management of patients with laryngeal/voice disorders. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy

    Science.gov (United States)

    Maski, Kiran; Steinhart, Erin; Williams, David; Scammell, Thomas; Flygare, Julie; McCleary, Kimberly; Gow, Monica

    2017-01-01

    Study Objectives: Describe common symptoms, comorbidities, functional limitations, and treatment responsiveness among patients with narcolepsy. Investigate the effect of pediatric onset of narcolepsy symptoms on time to diagnosis of narcolepsy and presence of comorbid depression. Methods: Cross-sectional survey of 1,699 people in the United States with self-reported diagnosis of narcolepsy. We utilized mixed-methods data analyses to report study findings. Results: Most participants reported receiving a diagnosis of narcolepsy more than 1 y after symptom onset. We found that the strongest predictor of this delayed diagnosis was pediatric onset of symptoms (odds ratio = 2.4, p narcolepsy symptoms. Overall, participants reported that fatigue and cognitive difficulties were their most burdensome symptoms in addition to sleepiness and cataplexy. The majority of participants reported residual daytime fatigue and/or sleepiness despite treatment. Most participants reported they could not perform at work or school as well as they would like because of narcolepsy symptoms. Conclusions: This study provides unique insight into the narcolepsy disease experience. The study quantifies the problem of diagnostic delay for narcolepsy patients in the United States and highlights that symptoms are more likely to be missed if they develop before 18 y of age. These results suggest that narcolepsy awareness efforts should be aimed at parents, pediatric health care providers, school professionals, and children/adolescents themselves. Disease burden is high because of problems with fatigue, cognition, and persistence of residual symptoms despite treatment. Citation: Maski K, Steinhart E, Williams D, Scammell T, Flygare J, McCleary K, Gow M. Listening to the patient voice in narcolepsy: diagnostic delay, disease burden and treatment efficacy. J Clin Sleep Med. 2017;13(3):419–425. PMID:27923434

  1. Comparing acoustic and perceptual voice parameters in female teachers based on voice complaints

    Directory of Open Access Journals (Sweden)

    Maryam Faghani Abukeili

    2014-04-01

    Full Text Available Background and Aim: Teachers are a large group of professional voice users that several risk factors and voice demands causes various voice complaints among them. As the voice is multidimensional, the aim of this study was acoustic and perceptual measurement of teachers’ voice and comparing the findings between two groups with many and few voice complaints.Methods: Sixty female teachers of high school in Sari, north of Iran, were chosen by available sampling to participate in this cross-sectional study. According to a voice complaints questionnaire, 21 subjects located in few voice complaints and 31 in many voice complaints group. After a working day, subjects completed a voice self-assessment questionnaire. Also, teachers’voice were recorded during three tasks including sustained vowels /a/ and /i/, text reading and conversational speech. Acoustic parameters were analyzed by Praat software and 2 speech-language pathalogists performed auditory-perceptual assessment by GRBAS ( Grade, Roughness, Breathiness, Asthenia, Strain scale. Results: Comparing of the voice self-assessment between the two groups demonstrated statistically significant difference (p<0.05; however results of the acoustic and auditory-perceptual measurement did not show significant diffrence.Conclusion: Despite prevalent voice problems in teachers, there are various conditions in terms of complaints and assessments methods. In this study, only a remarkable deviation documented in the client-based assessments in many voice compliants group in comparison with few voice compliants, which would be probably related to different individual’s perception of voice problem between two groups. These results support paying attention to self-assessments in clinical process of voice problems.

  2. The Role of Occupational Voice Demand and Patient-Rated Impairment in Predicting Voice Therapy Adherence.

    Science.gov (United States)

    Ebersole, Barbara; Soni, Resha S; Moran, Kathleen; Lango, Miriam; Devarajan, Karthik; Jamal, Nausheen

    2017-07-11

    Examine the relationship among the severity of patient-perceived voice impairment, perceptual dysphonia severity, occupational voice demand, and voice therapy adherence. Identify clinical predictors of increased risk for therapy nonadherence. A retrospective cohort study of patients presenting with a chief complaint of persistent dysphonia at an interdisciplinary voice center was done. The Voice Handicap Index-10 (VHI-10) and the Voice-Related Quality of Life (V-RQOL) survey scores, clinician rating of dysphonia severity using the Grade score from the Grade, Roughness Breathiness, Asthenia, and Strain scale, occupational voice demand, and patient demographics were tested for associations with therapy adherence, defined as completion of the treatment plan. Classification and Regression Tree (CART) analysis was performed to establish thresholds for nonadherence risk. Of 166 patients evaluated, 111 were recommended for voice therapy. The therapy nonadherence rate was 56%. Occupational voice demand category, VHI-10, and V-RQOL scores were the only factors significantly correlated with therapy adherence (P occupational voice demand are significantly more likely to be nonadherent with therapy than those with high occupational voice demand (P 40 is a significant cutoff point for predicting therapy nonadherence (P Occupational voice demand and patient perception of impairment are significantly and independently correlated with therapy adherence. A VHI-10 score of ≤9 or a V-RQOL score of >40 is a significant cutoff point for predicting nonadherence risk. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  3. Multipliers of Voice Campaign in Brasilia

    Directory of Open Access Journals (Sweden)

    Maria Lucia Graziano Magalhães Torres

    2012-12-01

    Full Text Available Report of the livings course experiments Technical and Resources of Expressiveness to talk to Public, promoted by NESPROM – CEAM – UNB in 2010-2011, addressing the topic of skills development to speak to the public with safety and confidence, as well as the importance of the use of the voice in this process. It can be observed that by providing students we see advances in expressiveness of the participants during the course and the commitment that perform to obtain a quality result, producing the material based on the information available on the website of the Brazilian society of speech therapy. All present themselves for a second time before the Facilitator, demonstrating safety and the use of the techniques learned. There was satisfaction with the gains on public speaking, even because, talk about a light object and that they all have, as the voice, brings security and trust for the apprentice. Ending a highlight poetry produced by one of the participants completing the course.

  4. Effects of time periods and astronomical tides on the onset of intracerebral hemorrhage in Rizhao region%时辰和天文潮汐对日照地区脑出血患者发病的影响

    Institute of Scientific and Technical Information of China (English)

    夏永梅; 叶红晖; 李向云; 厉郡华

    2013-01-01

    Objective To investigate the effects of time periods and astronomical tides on the onset of intracerebral hemorrhage in Rizhao region. Methods A total of 509 patients with intracerebral hemorrhage in Rizhao region were collected from January 1, 2006 to December 31, 2010. Using a circular distribution method, the concentration (r) of onset time of patients was calculated first, and then the mean ā an-gle and the dispersion angle (s) were calculated. The time and peak period of the onset of intracerebral hemorrhage were predicted at different time periods and different astronomical tidal periods ( new moon, full moon, first quarter, last quarter and other periods) . Rayleigh test was used for significant difference test. Results ①Among the 509 patients with intracerebral hemorrhage, 340 patients were occurred during the daytime (7:00 to 19 :00) and 169 patients during the night (19 :00 to 7:00) . The former was 2. 01 times than the later. The circular distribution analysis showed (-α) =205° ,Z = 32. 803 (P<0.001). When (-α) was at 11:00 to 13:00, it was the centralized time of the onset;s =94. 87°,(-α) ±s = 109.77° to 299.52°, the peak hours of onset were 5:00 to 19:00. ②117 patients had intracerebral hemorrhage during the new moon and full moon periods, 92 had intracerebral hemorrhage during the first quarter and last quarter periods, and 300 had intracerebral hemorrhage at the other times. The results of the circular distribution analysis showed (-α)= 53 ,27° ,Z =8. 0226 (P<0.001).(-α) in the new moon and full moon periods was the centralized time of the onset of intracerebral hemorrhage, s = 80. 16° ,(-α) ± s = -26. 89° to 133.43°, the peak hours were mainly the new moon, full moon, first quarter, and last quarter periods. Conclusion The distribution of intracerebral hemorrhage onset has circadian cycle rhythms. The onset during the daytime is higher than the night time,and associated with the changes of the astronomical tidal rhythms

  5. MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome.

    Science.gov (United States)

    Chen, Lin; Chen, Kaifu; Lavery, Laura A; Baker, Steven Andrew; Shaw, Chad A; Li, Wei; Zoghbi, Huda Y

    2015-04-28

    Epigenetic mechanisms, such as DNA methylation, regulate transcriptional programs to afford the genome flexibility in responding to developmental and environmental cues in health and disease. A prime example involving epigenetic dysfunction is the postnatal neurodevelopmental disorder Rett syndrome (RTT), which is caused by mutations in the gene encoding methyl-CpG binding protein 2 (MeCP2). Despite decades of research, it remains unclear how MeCP2 regulates transcription or why RTT features appear 6-18 months after birth. Here we report integrated analyses of genomic binding of MeCP2, gene-expression data, and patterns of DNA methylation. In addition to the expected high-affinity binding to methylated cytosine in the CG context (mCG), we find a distinct epigenetic pattern of substantial MeCP2 binding to methylated cytosine in the non-CG context (mCH, where H = A, C, or T) in the adult brain. Unexpectedly, we discovered that genes that acquire elevated mCH after birth become preferentially misregulated in mouse models of MeCP2 disorders, suggesting that MeCP2 binding at mCH loci is key for regulating neuronal gene expression in vivo. This pattern is unique to the maturing and adult nervous system, as it requires the increase in mCH after birth to guide differential MeCP2 binding among mCG, mCH, and nonmethylated DNA elements. Notably, MeCP2 binds mCH with higher affinity than nonmethylated identical DNA sequences to influence the level of Bdnf, a gene implicated in the pathophysiology of RTT. This study thus provides insight into the molecular mechanism governing MeCP2 targeting and sheds light on the delayed onset of RTT symptoms.

  6. Methods to study pre-school teachers' voice at work: simultaneous recordings with a voice accumulator and a DAT recorder.

    Science.gov (United States)

    Szabo, Annika; Hammarberg, Britta; Granqvist, Svante; Södersten, Maria

    2003-01-01

    Long-term recordings with reliable methods are desirable for objective documentation of voice use during natural conditions. The purpose of this study was to evaluate a voice accumulator (VAC) with a digital audiotape (DAT) recorder as a reference. The VAC is based on a microprocessor that accumulates information about fundamental frequency (F0) and phonation time. A contact microphone attached to the front of the neck registers vocal fold vibrations. The DAT recorder was connected to two microphones for airborne signals placed at equal distance from the mouth close to the subject's ears. The computer program Aura was used to separate the subject's voice from the background noise. The Soundswell program was used for F0 and phonation time analysis. Two tests were performed: 1) One female speech-language pathologist was recorded with the two devices simultaneously in a sound-proof booth. She read a standard text with different voice qualities and sustained vowels with increasing F0 and intensity separately. The results showed good agreement between the two methods with respect to F0 and phonation time. However, the VAC failed to register high frequencies above around 440 Hz as well as low intensities. 2) Three female pre-school teachers were recorded with the two devices simultaneously during a working day. Results showed high correlations between the two methods in terms of long-term measurements of F0 and phonation time for two subjects For one subject with subcutaneous soft tissue on the neck, the registration with the contact microphone was not reliable. It was concluded that the VAC has potential for assessment of occupational voice disorders if certain limitations of the method are considered.

  7. Perturbation Measures of Voice: A Comparative Study between Multi-Dimensional Voice Program and Praat

    National Research Council Canada - National Science Library

    Maryn, Youri; Corthals, Paul; De Bodt, Marc; Van Cauwenberge, Paul; Deliyski, Dimitar

    2009-01-01

    .... In the present study, perturbation measures provided by two computer systems (a purpose-built professional voice analysis apparatus and a personal computer-based system for acoustic voice assessment...

  8. [The smokers voice self assessment based on Voice Handicap Index (VHI)].

    Science.gov (United States)

    Wiskirska-Woźnica, Bozena; Wojnowski, Waldemar

    2009-01-01

    Complex voice assessment due to European Laryngeal Society proposals (2000) contains voice self estimation based on the Polish version of the Voice Handicap Index (VHI). This study focuses on the relation between voice handicap and smoking in dysphonic patients, who are using voice professionally. Thirty outpatient (25 female and 5 male, aged 40 to 55 years) voice department attendees suffering from professional dysphonia took part in this study. All patients after phoniatric examination completed the Polish version of the Voice Handicap Index (VHI). The questions concern functional, emotional and physical complains due to dysphonia. Most of smokers did not complain of dysphonia related problems comparing to non smokers. Even the scores of functional and emotional scales of VHI in smokers shown better results (less handicap) than in nonsmokers. Smoking does not affect patients handicap due to dysphonia measured in the Voice Handicap Index.

  9. Qos and Voice Over IP

    Directory of Open Access Journals (Sweden)

    Adrian GHENCEA

    Full Text Available As Voice over Internet Protocol (VoIP technology matures, companies are increasingly adopting it to cut costs, improve efficiency and enhance customer service. Using the Internet as an existing network for integrating data and telecom systems through intelligent VoIP, a range of benefits results: lower long distance costs, cost cuts in cabling processes and more flexible telephony management. However, as voice over IP services grow in popularity, major threats arise: this rapid growth leads to traffic congestion, security is jeopardizedand the poor quality of calls affects communication. The objective of this article is to present all the elements that can affect voicequality in a VoIP network and to provide methods for solving them. A detailed analysis to minimize the impact of implementation of QoS will be made, and at the end solutions to management strategies will be proposed.

  10. Effect of Religiosity on Voice.

    Science.gov (United States)

    Hamdan, Abdul-Latif; Khneisser, Gebran; Dowli, Alex; Ziade, Georges; Tamim, Hani

    2017-04-01

    The aim of this study was to examine the relationship between religiosity and phonatory behavior. A total of 186 participants participated in a survey that included four sections: demographic data, extent of religiosity, history of dysphonia, phonatory behavior and laryngeal manipulation, in addition to the Voice Handicap Index (VHI-10). There was no significant association between the prevalence of phonatory symptoms and any of the religiosity questions. There was no significant association between phonatory behavior, history of laryngeal manipulation and any of the religiosity questions. There was also no significant association between the score of the Voice Handicap Index and any of the five religiosity questions. There is no association between religiosity and prevalence of phonatory disturbances, phonotraumatic behavior and/or history of laryngeal manipulation.

  11. WHEEL CHAIR USING VOICE RECOGNITION

    OpenAIRE

    Manish Kumar Yadav*; Rajat Kumar; Santosh Yadav; Ravindra Prajapati; Prof. Kshirsagar

    2016-01-01

    The wide spread prevalence of lost limbs and sensing system is of major concern in present day due to wars, accident, age and health problems. This Omni-directional wheelchair was designed for the less able elderly to move more flexibly in narrow spaces, such as elevators or small aisle. The wheelchair is developed to help disabled patients by using speech recognition system to control the movement of wheelchair in different directions by using voice commands and also the simple movement of t...

  12. English Spoken Language & Voice Quality

    OpenAIRE

    Folsberg, Jens; Nielsen, Charlotte; Brusokaite, Giedre; Beinkamp, Line; Bach Jensen, Niels; Aalbæk Jensen, Sandra

    2013-01-01

    This project investigates the way language and accents are depicted in animated features and how linguistic stereotypes can be used in the process of character construction. In order to look into that, examples from four movies, produced by two studios, have been selected; the American Disney studios being represented by The Lion King (1994) and Up (2009), and the Japanese Studio Ghibli being represented by Ponyo (2008) and Howl's Moving Castle (2004). Voice qualities and specific accents ...

  13. Tracheostomy cannulas and voice prosthesis

    OpenAIRE

    2011-01-01

    Cannulas and voice prostheses are mechanical aids for patients who had to undergo tracheotomy or laryngectomy for different reasons. For better understanding of the function of those artificial devices, first the indications and particularities of the previous surgical intervention are described in the context of this review. Despite the established procedure of percutaneous dilatation tracheotomy e.g. in intensive care units, the application of epithelised tracheostomas has its own position,...

  14. The voice of the voiceless

    Directory of Open Access Journals (Sweden)

    Carlos Morales

    2014-12-01

    Full Text Available Women’s voice, these are stories of a group of women and their partners who lived part of a particular historical period agriculture during the twentieth century, the hacienda. The present work attempts to reflect their everyday life, reinterpreted from nowadays as a reflection of collective memory, in the big farms where they grew by putting in scene their roles in juxtaposition to the roles of male tradition.

  15. Adult onset tic disorders

    OpenAIRE

    Chouinard, S; Ford, B.

    2000-01-01

    BACKGROUND—Tic disorders presenting during adulthood have infrequently been described in the medical literature. Most reports depict adult onset secondary tic disorders caused by trauma, encephalitis, and other acquired conditions. Only rare reports describe idiopathic adult onset tic disorders, and most of these cases represent recurrent childhood tic disorders.
OBJECTIVE—To describe a large series of patients with tic disorders presenting during adulthood, to compare cl...

  16. Voice congruency facilitates word recognition.

    Directory of Open Access Journals (Sweden)

    Sandra Campeanu

    Full Text Available Behavioral studies of spoken word memory have shown that context congruency facilitates both word and source recognition, though the level at which context exerts its influence remains equivocal. We measured event-related potentials (ERPs while participants performed both types of recognition task with words spoken in four voices. Two voice parameters (i.e., gender and accent varied between speakers, with the possibility that none, one or two of these parameters was congruent between study and test. Results indicated that reinstating the study voice at test facilitated both word and source recognition, compared to similar or no context congruency at test. Behavioral effects were paralleled by two ERP modulations. First, in the word recognition test, the left parietal old/new effect showed a positive deflection reflective of context congruency between study and test words. Namely, the same speaker condition provided the most positive deflection of all correctly identified old words. In the source recognition test, a right frontal positivity was found for the same speaker condition compared to the different speaker conditions, regardless of response success. Taken together, the results of this study suggest that the benefit of context congruency is reflected behaviorally and in ERP modulations traditionally associated with recognition memory.

  17. Dysphonia: medical treatment and a medical voice hygiene advice approach. A prospective randomised pilot study.

    Science.gov (United States)

    Pedersen, M; Beranova, A; Møller, S

    2004-07-01

    For many years all patients with dysphonia referred to in the literature as resulting from non-organic (functional) voice disorders were sent to speech therapy. Medical diagnoses were not taken into account. In our earlier Cochrane review on vocal cord nodules we discovered that evidence-based research in the area of benign voice disorders with dysphonia, and with or without slight benign swellings including nodules on the vocal cords, was lacking at that time. Therefore, a prospective randomised pilot study based on our Cochrane review has been made on dysphonic patients with non-organic (function provoked?) voice disorders as the basis for further evidence-based studies. Medical treatment was based on the scientific approach that once a micro-organic disorder caused by reflux, infection, allergy or environmental irritatants (e.g., dust or noise in the workplace) was discovered by very careful anamnesis and systematic objective routine analyses and was treated effectively, with documentation, the non-organic voice disorder disappeared, as, e.g., in the case of a diagnosis and treatment of helicobakter pylori. The reason is that the mucosal swelling/dysfunction of the vocal cords is secondary. In order to try to understand why the recommendation to all these patients for many years was only voice therapy, which the speech therapists "felt to be effective", updated voice-hygiene advice (for posture, accents of the diaphragm, intonation pattern and resonance) was given by experienced laryngologists, randomised with the updated medical diagnosis/therapy in order to elucidate what effect the training might have. No evidence-based studies in the literature document any effect. The crucial point seemed to be that doctors mostly did not examine any other diagnoses other than the "dysphonia" and did not dig down to any of the medical reasons when the vocal fold diagnosis of "non- organic disorders" was made. This should be changed in the future. This pilot study was based

  18. Voices in (and around the Museum: Introduction

    Directory of Open Access Journals (Sweden)

    Ruth Holt

    2012-08-01

    Full Text Available The voice already plays an important role in contemporary art. This introductory paper summarises a series of four sessions in which speakers explored the place of the voice in the museum context. It became clear that the voice not only offered richness in interpretation of and response to other museum artefacts but was itself an artefact meriting conservation  and interpretation.

  19. Speak Up! But don't strain your voice

    Science.gov (United States)

    ... Disorders Speak Up! But don't strain your voice Past Issues / Fall 2008 Table of Contents For ... Javascript on. A clinical trial at the NIDCD Voice Center gave Sherdina Jones tools to limit voice ...

  20. Speaking up in groups: a cross-level study of group voice climate and voice.

    Science.gov (United States)

    Morrison, Elizabeth Wolfe; Wheeler-Smith, Sara L; Kamdar, Dishan

    2011-01-01

    Despite a growing body of research on employee voice—defined as the discretionary communication of ideas, suggestions, or opinions intended to improve organizational or unit functioning—the effects of shared or collective-level cognitions have received scant attention. There has also been relatively little research on voice within work groups. Our goal in this study was to address these important gaps by focusing on the effects of group-level beliefs about voice (i.e., group voice climate) on individual voice behavior within work groups. We conducted a cross-level investigation of voice behavior within 42 groups of engineers from a large chemical company. Consistent with our hypotheses, group voice climate was highly predictive of voice and explained variance beyond the effects of individual-level identification and satisfaction, and procedural justice climate. Also consistent with predictions, the effect of identification on voice was stronger in groups with favorable voice climates. These findings provide evidence that voice is shaped not just by individual attitudes and perceptions of the work context, as past research has shown, but also by group-level beliefs. The results also highlight the importance of broadening our conceptual models of voice to include shared cognitions and of conducting additional cross-level research on voice.

  1. Voice pathology detection using modulation spectrum optimized metrics

    Directory of Open Access Journals (Sweden)

    Laureano eMoro-Velazquez

    2016-01-01

    Full Text Available There exist many acoustic parameters employed for pathological assessment tasks, which have served as tools for clinicians to distinguish between normophonic and pathological voices. However, many of these parameters require an appropriate tuning in order to maximize its efficiency.In this work, a group of new and already proposed modulation spectrum metrics are optimized considering different time and frequency ranges pursuing the maximization of efficiency for the detection of pathological voices.The optimization of the metrics is performed simultaneously in two different voice databases in order to identify what tuning ranges produce a better generalization. The experiments were cross-validated so as to ensure the validity of the results. A third database is used to test the optimized metrics.In spite of some differences, results indicate that the behavior of the metrics in the optimization process follows similar tendencies for the tuning databases, confirming the generalization capabilities of the proposed modulation spectrum metrics. In addition, the tuning process reveals which bands of the modulation spectra have relevant information for each metric, which has a physical interpretation respecting the phonatory system. Efficiency values up to 90.6 % are obtained in one tuning database while in the other the maximum efficiency reaches 71.1 %.Obtained results also evidence a separability between normophonic and pathological states using the proposed metrics, which can be exploited for voice pathology detection or assessment.

  2. Pitch deviation analysis of pathological voice in connected speech.

    Science.gov (United States)

    Laflen, J Brandon; Lazarus, Cathy L; Amin, Milan R

    2008-02-01

    This study compares normal and pathologic voices using a novel voice analysis algorithm that examines pitch deviation during connected speech. The study evaluates the clinical potential of the algorithm as a mechanism to distinguish between normal and pathologic voices using connected speech. Adult vocalizations from normal subjects and patients with known benign free-edge vocal fold lesions were analyzed. Recordings had been previously obtained in quiet under controlled conditions. Two phrases and sustained /a/ were recorded per subject. The subject populations consisted of 10 normal and 31 abnormal subjects. The voice analysis algorithm generated 2-dimensional patterns that represent pitch deviation in time and under variable window widths. Measures were collected from these patterns for window widths between 10 and 250 ms. For comparison, jitter and shimmer measures were collected from sustained /a/ by means of the Computerized Speech Lab (CSL). A t-test and tests of sensitivity and specificity assessed discrimination between normal and abnormal populations. More than 58% of the measures collected from connected speech outperformed the CSL jitter and shimmer measures in population discrimination. Twenty-five percent of the experimental measures (including /a/) indicated significantly different populations (p connected speech.

  3. The electrolarynx: voice restoration after total laryngectomy.

    Science.gov (United States)

    Kaye, Rachel; Tang, Christopher G; Sinclair, Catherine F

    2017-01-01

    The ability to speak and communicate with one's voice is a unique human characteristic and is fundamental to many activities of daily living, such as talking on the phone and speaking to loved ones. When the larynx is removed during a total laryngectomy (TL), loss of voice can lead to a devastating decrease in a patient's quality of life, and precipitate significant frustration over their inability to communicate with others effectively. Over the past 50 years there have been many advances in techniques of voice restoration after TL. Currently, there are three main methods of voice restoration: the electrolarynx, esophageal speech, and tracheoesophageal speech through a tracheoesophageal puncture (TEP) with voice prosthesis. Although TEP voice is the current gold standard for vocal rehabilitation, a significant minority of patients cannot use or obtain TEP speech for various reasons. As such, the electrolarynx is a viable and useful alternative for these patients. This article will focus on voice restoration using an electrolarynx with the following objectives: 1) To provide an understanding of the importance of voice restoration after total laryngectomy. 2) To discuss how the electrolarynx may be used to restore voice following total laryngectomy. 3) To outline some of the current electrolarynx devices available, including their mechanism of action and limitations. 4) To compare pros and cons of electrolaryngeal speech to TEP and esophageal speech.

  4. The Performing Voice of the Audiobook

    DEFF Research Database (Denmark)

    Pedersen, Birgitte Stougaard; Have, Iben

    2014-01-01

    will be based on a reception aesthetic and phenomenological approach, the latter as presented by Don Ihde in his book Listening and Voice. Phenomenologies of Sound , and my analytical sketches will be related to theoretical statements concerning the understanding of voice and media (Cavarero, Dolar, La......Belle, Neumark). Finally, the article will discuss the specific artistic combination and our auditory experience of mediated human voices and sculpturally projected faces in an art museum context under the general conditions of the societal panophonia of disembodied and mediated voices, as promoted by Steven...

  5. Methods of Translating the English passive voice

    Institute of Scientific and Technical Information of China (English)

    张李丽

    2009-01-01

    @@ 一、Comparisons between Voices in English and Chinese In English as in many other languages,the passive voice is the form of a transitive verb whose grammatical sabjOct serves as the patient,receiving the action of the verb.The passive voice is typically contrasted with the active voice,which is the form of a transitive verb whose subject serves as the agent,performing the action of the verb.The subject of a verb in the passive voice corresponds to the object of the same verb in the active voice.English's passive voice is periphrastic;that is,it does not have a one-word form.Rather,it is formed using a form of the auxiliary verb be together with a verb's past participle.The passive voice is widely used in English when it is unnecessary,undesirable,or impossible to ilame the agent of an action,or when the passive voice is needed to link the text better.

  6. Prevalence of voice disorders among future teachers.

    Science.gov (United States)

    Simberg, S; Laine, A; Sala, E; Rönnemaa, A M

    2000-06-01

    An epidemiological study was conducted in order to find out the prevalence of voice disorders among students studying to be teachers. Vocal symptoms were inquired of 226 students. Their voices were assessed perceptually by a speech therapist and those who had abnormal voice quality or reported several vocal symptoms were referred to a clinical examination by a laryngologist. The results showed that 20% of this population reported two or more vocal symptoms during the previous year and that 19% had an organic voice disorder. This reinforces the need for clinical evaluation of students with vocal symptoms and more vocal training in the teacher education programs.

  7. Restoration of voice function by using biological feedback in laryngeal and hypopharyngeal carcinoma patients

    Science.gov (United States)

    Choinzonov, E. L.; Balatskaya, L. N.; Chizhevskaya, S. Yu.; Meshcheryakov, R. V.; Kostyuchenko, E. Yu.; Ivanova, T. A.

    2016-08-01

    The aim of the research is to develop and introduce a new technique of post-laryngectomy voice rehabilitation of laryngeal and hypopharyngeal carcinoma patients. The study involves comparing and analyzing 82 cases of voice function restoration by using biological feedback based on mathematical modeling of voice production. The advantage of the modern technology-based method in comparison with the conventional one is proved. Restoration of voice function using biofeedback allows taking into account patient's abilities, adjusting parameters of voice trainings, and controlling their efficiency in real-time mode. The data obtained indicate that the new method contributes to the rapid inclusion of self-regulation mechanisms of the body and results in the overall success rate of voice rehabilitation in totally laryngectomized patients reaching 92%, which reduces the rehabilitation period to 18 days, compared to 86% and 38 days in the control group, respectively. Restoration of disturbed functions after successful treatment is an important task of rehabilitation and is crucial in terms of the quality of cancer patients' lives. To assess life quality of laryngeal cancer patients, the EORTC Quality of Life Core Questionnaire (QLQ-C30), and head and neck module (QLQ-H&N35) were used. The analyzed results proved that the technique of biofeedback voice restoration significantly improves the quality of life of laryngectomized patients. It allows reducing the number of disabled people, restoring patients' ability to work-related activities, and significantly improving social adaptation of these patients.

  8. [Epidemiological investigation and correlation factors analysis of voice diseases of 5758 business dealers].

    Science.gov (United States)

    Lou, Zhengcai; Zhu, Qiaoying; Zong, Huiqin; Fu, Weiqing; Zhang, Jian

    2008-02-01

    To investigate the epidemic features and risk factors of voice diseases of 5758 business dealers. Questionnaire survey was conducted among 5785 business dealers of four markets in Yiwu city by random cluster sampling from March to July, 2006. They were also examined by indirect laryngoscopy. The incidence of voice disease was calculated and the risk factors were evaluated in four markets. The incidence of voice disease was 39.3%, 18.8%, 28.4% and 58.1% in garment market, crafts market, stock market, and vegetable market, respectively. The average incidence was 30.4% in four markets. The difference of incidence among four markets was statistically significant (P market. Chronic laryngitis and polyp of vocal cord were found to be the major pathological manifestations in men, while Chronic laryngitis and vocal nodules were found to be the major pathological manifestations in women. In addition, laryngeal carcinoma was confirmed in 8 cases. Market noise, pollution, unhealthy habits of business trade and excessive voice were the high risk factors. The female and the business dealers aged from 30 to 50 were the high risk people. Varied relevant measures should be taken to prevent and control voice disease in different subgroups of population. People should be examined thoroughly as soon as they got voice problem. Improvement of market environment and timely intervention may reduce the prevalence rate of voice disease.

  9. WORKERS FINDING A VOICE

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The recent cases of U.S. fast-food giants McDonald’s and KFC, accused of underpaying and exploiting part-time workers in their Chinese branches, have put labor relations under the spotlight. With deepening market-oriented economic reforms and an increasi

  10. Probability of regaining dexterity in the flaccid upper limb - Impact of severity of paresis and time since onset in acute stroke

    NARCIS (Netherlands)

    Kwakkel, G; Kollen, BJ; van der Grond, J; Prevo, AJH

    2003-01-01

    Background and Purpose-To improve the accuracy of early postonset prediction of motor recovery in the flaccid hemiplegic arm, the effects of change in motor function over time on the accuracy of prediction were evaluated, and a prediction model for the probability of regaining dexterity at 6 months

  11. [The impact of voice on the quality of life of elementary school teachers].

    Science.gov (United States)

    Grillo, Maria Helena Marotti Martelletti; Penteado, Regina Zanella

    2005-01-01

    Relationship between voice and quality of life. To assess the impact of voice on the quality of life of elementary public school teachers. Application of the Voice-related quality of life questionnaire (VRQOL) with 120 teachers. The analysis involves: calculation of the Global Score (questions 1 to 10); descriptive analysis of the questions; calculation of Spearman's correlation coefficient between the Global Score, the question "how do you evaluate your voice?", age, teaching career (period of time) and teaching schedule. The average Global Score of the VRQOL was 84.2. Most of the teachers (49.2%) considered their voice as good, although they face difficulties when speaking, especially when having to speak louder in noisy environments. They also run out of breath quickly, having to breathe constantly while speaking (questions 1 and 2, respectively). The isolated question presented a significant linear correlation with all the other questions of the VRQOL, whereas age and teaching schedule did not present a significant correlation with any of the questions. Teaching career presented correlation with questions 2 and 5, regarding lack of breath and depression respectively. Based on the results, the impact of voice on the quality of life becomes evident when considering the use of voice at high intensities, coordination between breathing and speaking in the work environment and in the negative feelings, which are directly related to the vocal needs of these professionals. The impact of voice in the quality of life and work is still fairly noticed by teachers who demonstrate to have vocal needs. These vocal needs require health promotion actions which take into consideration the relationship between voice and the quality of life of teachers.

  12. Is the time between onset of pain and restoration of patency of infarct-related artery shortened in patients with myocardial infarction? The effects of the Kielce Region System for Optimal Management of Acute Myocardial Infarction

    Directory of Open Access Journals (Sweden)

    Marcin Sadowski

    2014-09-01

    Full Text Available Introduction : The importance of delay in the restoration of infarct-related artery patency in patients with myocardial infarction was discussed, and actions were undertaken in the Kielce Region aimed at shortening this time within the System for Optimal Management of Acute Myocardial Infarction. Aim of the research: To evaluate the effectiveness of shortening time delays during transport of patients and diagnostics of myocardial infarction in the Kielce Region. Material and methods: Time delays were analysed in 5,934 patients with ST-segment elevation myocardial infarction (STEMI, hospitalised in cardiology wards with interventional cardiology on 24-hour duty, during the period 2008–2012. Time delays were analysed between the onset of myocardial infarction pain and undertaking treatment – T1 and T2 time – within which a patient with myocardial infarction, after admission to hospital, has intervention performed on infarct-related coronary artery. Results : During the period 2008–2012, the median T1 time was successfully shortened from 355 to 203 min, and the T2 time from 101 to 48 min. Conclusions: The effectiveness of the system was confirmed, and the necessity for further improvement of the system indicated.

  13. The design of a digital voice data compression technique for orbiter voice channels

    Science.gov (United States)

    1975-01-01

    Voice bandwidth compression techniques were investigated to anticipate link margin difficulties in the shuttle S-band communication system. It was felt that by reducing the data rate on each voice channel from the baseline 24 (or 32) Kbps to 8 Kbps, additional margin could be obtained. The feasibility of such an alternate voice transmission system was studied. Several factors of prime importance that were addressed are: (1) achieving high quality voice at 8 Kbps; (2) performance in the presence of the anticipated shuttle cabin environmental noise; (3) performance in the presence of the anticipated channel error statistics; and (4) minimal increase in size, weight, and power over the current baseline voice processor.

  14. Voice training in teacher education: the effect of adding an individualized microteaching session of 30 minutes to the regular 6-hour voice training program.

    Science.gov (United States)

    Timmermans, B; Coveliers, Y; Wuyts, F L; Van Looy, L

    2012-09-01

    In a previous study, we investigated the effect of a twofold voice-training module in student teachers. In the present study, the original training module of 3 hours of indirect and 3 hours of direct group training was expanded with a 30-minute individual counseling session for each participant. The main focus was on the effects of this threefold training paradigm on the voice of the participants. The subjects were 81 students at the academic teaching program at the Vrije Universiteit Brussel. The trained group (n=51) received the entire voice-training program, whereas the control group (n=30) received no voice training at all. A multidimensional test battery consisting of subjective evaluation and objective measurements was applied to both the groups at the study onset and again 4 months later to assess training results. Other than an improvement in the parameter strain, no significant change was observed for the subjective judgments. Several of the objective parameters did however improve in the trained group only, most significantly in female subjects. The impact of the 30-minute individual counseling session was small and differed for males and females. However, the results support the effectiveness of this training module and favor its introduction in the education of student teachers.

  15. Voice communications over packet radio networks

    Science.gov (United States)

    Seah, M. M.

    1985-03-01

    The use of packet virtual circuit technique for voice communications in military radio networks was investigated. The work was concerned with various aspects of networking which include network modeling, communications techniques, traffic analysis and network control. An attempt has been made to develop a simple yet efficient time slot assignment algorithm . This was analyzed under a variety of slot depths and networks topologies using computer simulation. The Erlang' B results were used to provide more insight into the channel characteristics of the packet radio networks. The capabilities of implementing TDMA/CDMA hybrid schemes in the system were scrutinized. A method to estimate the transmission capacity of the inter-node links was found. We demonstrate its effectiveness in controlling local congestion by computer simulation. Graphical results were presented to highlight the behavior of the proposed packet radio networks. We concluded that an appropriate link weight function would provide efficient and reliable network services.

  16. Impact of PACS and Voice-Recognition Reporting on the Education of Radiology Residents

    OpenAIRE

    Gutierrez, Antonio J.; Mullins, Mark E.; Robert A. Novelline

    2005-01-01

    Rationale and Objectives: The introduction of picture archiving and communication system (PACS) has decreased the time needed to interpret radiology examinations resulting in an increased workflow. Because of concerns that the increase in exam throughput and the use of voice recognition may have a negative impact upon radiology resident education, a survey was conducted to assess the impact of PACS and voice recognition. Materials and Methods: Residents at four diagnostic radiology training p...

  17. The Effect of Increased Vocal Intensity on Interarticulator Timing in Speakers with Parkinson’s Disease: A Preliminary Analysis

    Science.gov (United States)

    Richardson, Kelly; Sussman, Joan E.; Stathopoulos, Elaine T.; Huber, Jessica E.

    2014-01-01

    Purpose The purpose of the current study was to investigate the effect of increased vocal intensity on interarticulator timing in individuals with Parkinson’s disease (PD). Methods Ten individuals with mild to moderate hypophonia, secondary to PD, were selected for study. Over an 8-week treatment period, multi-talker babble noise was presented monaurally to the individuals with PD during everyday communication contexts to elicit increased vocal intensity (Lombard effect). Outcome measures included sound pressure level (SPL), voice onset time (VOT), VOT ratio, percent voicing, and speech intelligibility. Results Group and individual participant responses to the treatment are reported and discussed. Speakers with PD were shown to significantly increase SPL in response to treatment. Six of the ten speakers showed improved temporal coordination between the laryngeal and supralaryngeal mechanisms (interarticulator timing) in response to treatment. Four of the ten speakers, however, showed reduced laryngeal-supralaryngeal timing at the end of treatment. Group speech intelligibility scores were significantly higher post-treatment as compared to pre-treatment. Conclusions Voice treatment during everyday communication resulted in improved temporal coordination across the laryngeal and supralaryngeal mechanisms for the majority of speakers with PD and made them easier to understand. Further investigations are planned to explore individual differences in response to treatment. The identification of speaker-specific voicing and devoicing strategies is consistent with the heterogeneous nature of PD. PMID:25459460

  18. Circadian period and the timing of melatonin onset in men and women: predictors of sleep during the weekend and in the laboratory.

    Science.gov (United States)

    Lazar, Alpar S; Santhi, Nayantara; Hasan, Sibah; Lo, June C-Y; Johnston, Jonathan D; Von Schantz, Malcolm; Archer, Simon N; Dijk, Derk-Jan

    2013-04-01

    Sleep complaints and irregular sleep patterns, such as curtailed sleep during workdays and longer and later sleep during weekends, are common. It is often implied that differences in circadian period and in entrained phase contribute to these patterns, but few data are available. We assessed parameters of the circadian rhythm of melatonin at baseline and in a forced desynchrony protocol in 35 participants (18 women) with no sleep disorders. Circadian period varied between 23 h 50 min and 24 h 31 min, and correlated positively (n = 31, rs  = 0.43, P = 0.017) with the timing of the melatonin rhythm relative to habitual bedtime. The phase of the melatonin rhythm correlated with the Insomnia Severity Index (n = 35, rs  = 0.47, P = 0.004). Self-reported time in bed during free days also correlated with the timing of the melatonin rhythm (n = 35, rs  = 0.43, P = 0.01) as well as with the circadian period (n = 31, rs  = 0.47, P = 0.007), such that individuals with a more delayed melatonin rhythm or a longer circadian period reported longer sleep during the weekend. The increase in time in bed during the free days correlated positively with circadian period (n = 31, rs  = 0.54, P = 0.002). Polysomnographically assessed latency to persistent sleep (n = 34, rs  = 0.48, P = 0.004) correlated with the timing of the melatonin rhythm when participants were sleeping at their habitual bedtimes in the laboratory. This correlation was significantly stronger in women than in men (Z = 2.38, P = 0.017). The findings show that individual differences in circadian period and phase of the melatonin rhythm associate with differences in sleep, and suggest that individuals with a long circadian period may be at risk of developing sleep problems.

  19. Muscular tension and body posture in relation to voice handicap and voice quality in teachers with persistent voice complaints.

    Science.gov (United States)

    Kooijman, P G C; de Jong, F I C R S; Oudes, M J; Huinck, W; van Acht, H; Graamans, K

    2005-01-01

    The aim of this study was to investigate the relationship between extrinsic laryngeal muscular hypertonicity and deviant body posture on the one hand and voice handicap and voice quality on the other hand in teachers with persistent voice complaints and a history of voice-related absenteeism. The study group consisted of 25 female teachers. A voice therapist assessed extrinsic laryngeal muscular tension and a physical therapist assessed body posture. The assessed parameters were clustered in categories. The parameters in the different categories represent the same function. Further a tension/posture index was created, which is the summation of the different parameters. The different parameters and the index were related to the Voice Handicap Index (VHI) and the Dysphonia Severity Index (DSI). The scores of the VHI and the individual parameters differ significantly except for the posterior weight bearing and tension of the sternocleidomastoid muscle. There was also a significant difference between the individual parameters and the DSI, except for tension of the cricothyroid muscle and posterior weight bearing. The score of the tension/posture index correlates significantly with both the VHI and the DSI. In a linear regression analysis, the combination of hypertonicity of the sternocleidomastoid, the geniohyoid muscles and posterior weight bearing is the most important predictor for a high voice handicap. The combination of hypertonicity of the geniohyoid muscle, posterior weight bearing, high position of the hyoid bone, hypertonicity of the cricothyroid muscle and anteroposition of the head is the most important predictor for a low DSI score. The results of this study show the higher the score of the index, the higher the score of the voice handicap and the worse the voice quality is. Moreover, the results are indicative for the importance of assessment of muscular tension and body posture in the diagnosis of voice disorders.

  20. Possible link of sudden onset and short-time periodic pulsation of polar mesosphere summer echoes to ULF Pc5 geomagnetic pulsations and solar wind dynamic pressure enhancement

    Science.gov (United States)

    Lee, Y.; Kirkwood, S.; Kwak, Y. S.

    2016-12-01

    The EISCAT VHF incoherent scatter radar in Tromsö, Norway, makes occasional observations of electron densities and Polar Mesosphere Summer Echoes, in the summer polar D-region ionosphere. In one of those datasets, pulsating polar mesospheric summer echoes (PMSE) are observed, with periodicities in the ultra-low frequency (ULF) Pc5 band (1.6-6.7 mHz), following an abrupt increase of the radar reflectivity when a geomagnetic field excursion is started, in turn linked to dynamic pressure (Pdyn) enhancement in the solar wind. At the excursion of the magnetic field, at auroral altitudes of 90 km and above, electron density is abruptly enhanced, followed by a series of short-lived peaks, superimposed on an enhanced level. The short-lived peaks are likely a signature of transient Pc5 geomagnetic pulsations and associated energetic electron precipitation from pitch-angle scattering into the loss cone in the magnetosphere. At the same time, at altitudes around 80-90 km, a sharp increase of PMSE reflectivity occurs, 100 times greater than the increase of electron density, and is followed by pulsating PMSE reflectivity with periodicities in the Pc5 band, increasing and decreasing in magnitude during the course of the next hour. The increase of the pulsation magnitude may be attributed to an increase of high-energy electron precipitation flux ( >30 keV) penetrating to at least the height of maximum PMSE reflectivity. This study suggests that Pc5 pulsation bursts in both magnetic field and high energy electron precipitation could play a crucial role in producing PMSE fluctuations on minute-to-minute time scales.