WorldWideScience

Sample records for voice coil diameter

  1. Low Impedance Voice Coils for Improved Loudspeaker Efficiency

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold; Andersen, Michael A. E.

    2015-01-01

    In modern audio systems utilizing switch-mode amplifiers the total efficiency is dominated by the rather poor efficiency of the loudspeaker. For decades voice coils have been designed so that nominal resistances of 4 to 8 Ohms is obtained, despite modern audio amplifiers, using switch-mode techno......In modern audio systems utilizing switch-mode amplifiers the total efficiency is dominated by the rather poor efficiency of the loudspeaker. For decades voice coils have been designed so that nominal resistances of 4 to 8 Ohms is obtained, despite modern audio amplifiers, using switch......-mode technology, can be designed to much lower loads. A thorough analysis of the loudspeaker efficiency is presented and its relation to the voice coil fill factor is described. A new parameter, the drivers mass ratio, is introduced and it indicates how much a fill factor optimization will improve a driver......’s efficiency. Different voice coil winding layouts are described and their fill factors analyzed. It is found that by lowering the nominal resistance of a voice coil, using rectangular wire, one can increase the fill factor. Three voice coils are designed for a standard 10” woofer and corresponding frequency...

  2. Voice Coil Percussive Mechanism Concept for Hammer Drill

    Science.gov (United States)

    Okon, Avi

    2009-01-01

    A hammer drill design of a voice coil linear actuator, spring, linear bearings, and a hammer head was proposed. The voice coil actuator moves the hammer head to produce impact to the end of the drill bit. The spring is used to store energy on the retraction and to capture the rebound energy after each impact for use in the next impact. The maximum actuator stroke is 20 mm with the hammer mass being 200 grams. This unit can create impact energy of 0.4 J with 0.8 J being the maximum. This mechanism is less complex than previous devices meant for the same task, so it has less mass and less volume. Its impact rate and energy are easily tunable without changing major hardware components. The drill can be driven by two half-bridges. Heat is removed from the voice coil via CO2 conduction.

  3. Low Impedance Voice Coils for Improved Loudspeaker Efficiency

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold; Andersen, Michael A. E.

    2015-01-01

    In modern audio systems utilizing switch-mode amplifiers the total efficiency is dominated by the rather poor efficiency of the loudspeaker. For decades voice coils have been designed so that nominal resistances of 4 to 8 Ohms is obtained, despite modern audio amplifiers, using switch...

  4. Relationship between voice coil fill factor and loudspeaker efficiency

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold; Andersen, Michael A. E.

    2016-01-01

    In modern audio systems, utilizing switch-mode amplifiers, the total efficiency is dominated by the rather poor efficiency of the loudspeaker. For decades voice coils have been designed so that nominal resistances of 3 to 8 Ω are obtained, despite modern audio amplifiers, using switch...

  5. Relationsssship between voice coil fill factor and loudspeaker efficiency

    DEFF Research Database (Denmark)

    Iversen, Niels Elkjær; Knott, Arnold; Andersen, Michael A. E.

    2016-01-01

    In modern audio systems, utilizing switch-mode amplifiers, the total efficiency is dominated by the rather poor efficiency of the loudspeaker. For decades voice coils have been designed so that nominal resistances of 3 to 8 Ω are obtained, despite modern audio amplifiers, using switch...

  6. Design of Electromagnetic Moving-coil type Voice Coil Motor for Scanning mirror of Barcode reader

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Bu Hyun; Lee, Jeong Woo; Shim, Hyun Ho; Park, Sang Goo [Hanbat National Univ., Daejeon (Korea, Republic of); Lee, Seung Yop [Sogang Univ., Seoul (Korea, Republic of)

    2016-01-15

    A voice coil actuator with moving coil type for scanning mirror system of barcode reader has been developed. The actuator has a simple structure including a magnet, a coil and a pin. The performance of the actuator is analyzed by a linearized theoretical model. And the dynamic performance of the proposed actuator is predicted through motor constant and restoring constant obtained by finite element simulations. The theoretical model was verified by the prototype which has 64 Hz resonance frequency and 60 deg reflecting angle. We also discovered that that 3 V input can make the actuator rotate over 61.8 deg reflecting angle at 50 Hz resonance frequency. The proposed actuator can simplify its driving configuration because of its implementation of open-loop control.

  7. Voice Coil Actuator for Active Vibration Isolation in Microgravity

    Science.gov (United States)

    Brusa, E.; Carabelli, S.; Genta, G.; Maddaleno, F.; Silvagni, M.; Tonoli, A.

    2002-01-01

    Many microgravity experiments require very low levels of acceleration which cannot be achieved on the International Space Station due to the residual vibration. A vibration isolation system is then usually devised between the experiment and the space station to obtain the desired accelerations at the experiment level. The very low frequency threshold required by the isolation specifications makes passive solutions for the isolation difficult to implement. This is mainly due to the practical impossibility of achieving high values of compliance of the elastic suspension. Furthermore, the unavoidable connections of uncertain characteristics between the experiment and the space station makes the problem even more difficult to be addressed. Disturbance reduction can be performed by means of active vibration isolation, based on magnetic suspension technology acting both at rack and at scientific experiment levels. The stiffness and damping of the active suspension can be tuned by the control loop to minimise the acceleration of the payload. The mechatronic design of an active magnetic suspension for vibration isolation in microgravity has been performed by resorting to the so-called voice-coil configuration, after a preliminary trade-off analysis of the available magnetic actuators and materials. The optimisation of the actuator layout was developed with respect to the design airgap and force density (N/kg of actuator) and force resolution requirements, by demonstrating that the configuration based on Lorentz magnetic force is more suitable for the above application in terms of stability, bi- directionality of the actuation, cross coupling effects and linearity of the force. The aim of the design was the maximisation of the actuation force/mass ratio. The FEM analysis of the voice coil allowed to investigate the flux leakage and the cross coupling effects between the actuation forces along the three principal directions of the active device. A procedure for the numerical

  8. [Importance of an automatic measurement base on the first coil diameter in regard to coil embolization of a cerebral aneurysm].

    Science.gov (United States)

    Kuriyama, Takumi; Furukawa, Hajime; Shimizu, Keiji; Oonishi, Kumiko; Sakai, Shinji; Imamura, Hirotoshi; Sakai, Chiaki; Sakai, Nobuyuki

    2012-01-01

    We compared the accuracy in evaluating an unrapture aneurysm between NV and 3D-DSA. In vitro, we evaluated the accuracy in calculating the volume of the Aneurysm model. We compared the diameter of the first coil and estimated the diameter of the Aneurysm. The Aneurysm size calculated by NV resembled the first coil more than the size measured by 3D-DSA. In clinical cases, the measurement of NV is objective; the measurement of 3D-DSA, however, is subjective by person. NV has an automatic measurement that is useful for clinical cases.

  9. The linear position tracking servo system using a linear voice-coil motor

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    More and more linear servo systems have been used in servo applications. Direct drive technology can greatly increase the bandwidth and the tracking accuracy. A position servo-system based on linear voice-coil motor was designed for one linear oscillation movement application. Besides the conventional position, speed and current control loops, the speed and acceleration feed-forward control of command position signal were also used. The experimental test proved the correctness of the design, and the system can track the given periodic sinnsoid position command signal of 15Hz with high accuracy. The linear voice-coil motor is very suitable for short stroke position tracking application with high dynamic response.

  10. Active Vibration Isolation Using a Voice Coil Actuator with Absolute Velocity Feedback Control

    OpenAIRE

    Yun-Hui Liu; Wei-Hao Wu

    2013-01-01

    This paper describes the active vibration isolation using a voice coil actuator with absolute velocity feedback control for highly sensitive instruments (e.g., atomic force microscopes) which suffer from building vibration. Compared with traditional isolators, the main advantage of the proposed isolation system is that it produces no isolator resonance. The absolute vibration velocity signal is acquired from an accelerator and processed through an integrator, and is then input to the controll...

  11. The linear position tracking servo systemusing a linear voice-coil motor

    Institute of Scientific and Technical Information of China (English)

    褚立新; 林辉

    2008-01-01

    More and more linear servo systems have been used in servo applications. Direct drive technology can greatly increase the bandwidth and the tracking accuracy. A position servo-system based on linear voice-coil motor was designed for one linear oscillation movement application. Besides the conventional position, speed and current control loops, the speed and acceleration feed-forward control of command position signal were also used. The experimental test proved the correctness of the design, and the system ...

  12. Study and Design of a Linear Compressor of Voice-Coil Typ

    Directory of Open Access Journals (Sweden)

    VADAN, I.

    2009-06-01

    Full Text Available The paper presents the design and Finite Element (FEM analysis of a Linear compressor of voice coil type (LCVCT. This kind of linear compressor will be used in a refrigerator equipment. It is well-known that the replacing of the rotating compressor from a classical refrigerator by a linear compressor leads to an efficiency improving wit about 5% by avoiding the piston side friction, which is very important because of the huge number of refrigerators in operation world-wide. The linear compressor refrigerator is already commercially available in South Korea, equipped with an electromagnetic (fix coil and moving permanent magnet linear compressor. This paper presents a new type of linear compressor - a voice-coil type (fixed permanent magnet and moving coil. The operation principle is the same as for electrodynamic vibrator or electro-dynamic loud-speaker. The designing with rare earth permanent magnet is not a simple problem, because of the nonlinear characteristic of rare earth magnets. A magneto-static FEM analysis has been performed in order to validate the design methodology proposed in the paper.

  13. Research and Application of Voice Coil Motor%音圈电机研究及应用综述

    Institute of Scientific and Technical Information of China (English)

    兴连国; 周惠兴; 侯书林; 曹荣敏

    2011-01-01

    Voice coil motor is a special type of linear motor, which is similar to the voice coil of loudhailer in terms of working principle. Voice coil motor is a transmission-free device. The electrical energy can be directly converted into mechanical energy. Voice coil motor is characterized by being of high acceleration, high speed, smooth force, fast response, small-volume, light-weigh. The theoretical basis for the design and selection was provided in this paper. Working principle, topology form, design methods, control algorithms and heat balance of voice coil motor were introduced in detail. Design and calculation methods of voice coil motor were given. Finally the application and recent studies of voice coil motor were presented.%音圈电机是特种直线电机,是一种将电能直接转化为直线或者圆弧运动机械能而不需要任何中间转换机构的传动装置,其工作原理与扬声器的音圈类似.音圈电机具有体积小、重量轻、高加速度、高速度、快速响应、推力均匀等优良性能.介绍了音圈电机的设计与选用的理论基础,并阐述了音圈电机的技术工作原理、结构形式、设计方案、控制方法和热平衡分析.给出了音圈电机的设计计算方法,并对音圈电机的应用场合进行了详细介绍.

  14. Voice Coil Motor Position Control Based on Feed-forward Fuzzy PID

    Institute of Scientific and Technical Information of China (English)

    尹峰松

    2016-01-01

    Conventional PID algorithm is unable to track the response with high frequency,and has obvious overshoot in some voice coil motor practical applications.So,combined with the fuzzy PID control theory,we can obtain the precise control by the method.Meanwhile,through the feed-forward control,the performance of quick response and dynamic tracking can be improved.Thus,this control method not only maintains the excellent performance of the controller,but also improves the stability of the system.

  15. Composite Motion Design Procedure for Vibration Assisted Small-Hole EDM Using One Voice Coil Motor

    Directory of Open Access Journals (Sweden)

    Jing Cui

    2016-01-01

    Full Text Available To address the problem of debris accumulation in small-hole electrical discharge machine (EDM and simplify the design of the spindle head, the paper proposes a novel composite motion design procedure integrated high frequency vibration and large stroke feed using one voice coil motor (VCM. Particularly, for the purposes of high servo accuracy and high frequency response of the composite motion, an improved zero-phase-error tracking controller (ZPETC algorithm decoupled with the feedback controller is developed for the process control, in which the feedback parameter adjustment is very simple to reduce the computation complexity. At last, the proposed procedure is validated by the experimental study of the established VCM positioning table; the results verify the efficiency of the proposed method.

  16. Design and evaluation of coils for a 50 mm diameter induction coilgun launcher

    Energy Technology Data Exchange (ETDEWEB)

    Kaye, R.J.; Shokair, I.R.; Wavrik, R.W. [Sandia National Labs., Albuquerque, NM (United States); Dempsey, J.F.; Honey, W.E.; Shimp, K.J. [EG and G, Inc., Albuquerque, NM (United States); Douglas, G.M. [Rockwell Power Systems Co., Albuquerque, NM (United States)

    1993-12-31

    Coilguns have the ability to provide magnetic pressure to projectiles which results in near constant acceleration. However, to achieve this performance and control projectile hearing, significant constraints are placed on the design of the coils. We are developing coils to produce an effective projectile base pressure of 100 MPa (1kbar) as a step toward reaching base pressures of 200 MPa. The design uses a scalable technology applicable to the entire range of breech to muzzle coils of a multi-stage launcher. This paper presents the design of capacitor-driven coils for launching nominal 50 mm, 350 gram projectiles. Design criteria, constraints, mechanical stress analysis, launcher performance, and test results are discussed.

  17. Voice-coil technology for the E-ELT M4 Adaptive Unit

    Science.gov (United States)

    Gallieni, D.; Tintori, M.; Mantegazza, M.; Anaclerio, E.; Crimella, L.; Acerboni, M.; Biasi, R.; Angerer, G.; Andrigettoni, M.; Merler, A.; Veronese, D.; Carel, J.-L.; Marque, G.; Molinari, E.; Tresoldi, D.; Toso, G.; Spanó, P.; Riva, M.; Mazzoleni, R.; Riccardi, A.; Mantegazza, P.; Manetti, M.; Morandini, M.; Vernet, E.; Hubin, N.; Jochum, L.; Madec, P.; Dimmler, M.; Koch, F.

    We present our design of the E-ELT M4 Adaptive Unit based on voice-coil driven deformable mirror technology. This technology was developed by INAF-Arcetri, Microgate and ADS team in the past 15 years and it has been adopted by a number of large ground based telescopes as the MMT, LBT, Magellan and lastly the VLT in the frame of the Adaptive Telescope Facility project. Our design is based on contactless force actuators made by permanent magnets glued on the back of the deformable mirror and coils mounted on a stiff reference structure. We use capacitive sensors to close a position loop co-located with each actuator. Dedicated high performance parallel processors are used to implement the local de-centralized control at actuator level and a centralized feed-forward computation of all the actuators forces. This allowed achieving in our previous systems dynamic performances well in line with the requirements of the M4 Adaptive Unit (M4AU) case. The actuator density of our design is in the order of 30-mm spacing for a figure of about 6000 actuators on the M4AU and it allows fulfilling the fitting error and corrections requirements of the E-ELT high order DM. Moreover, our contact-less technology makes the Deformable Mirror tolerant to up 5% actuators failures without spoiling system capability to reach its specified performances, besides allowing large mechanical tolerances between the reference structure and the deformable mirror. Finally, we present the Demonstration Prototype we are building in the frame of the M4AU Phase B study to measure the optical dynamical performances predicted by our design. Such a prototype will be fully representative of the M4AU features, in particular it will address the controllability of two adjacent segments of the 2-mm thick mirror and implement the actuators "brick" modular concept that has been adopted to dramatically improve the maintainability of the final unit.

  18. Design of voice coil motor dynamic focusing unit for a laser scanner.

    Science.gov (United States)

    Lee, Moon G; Kim, Gaeun; Lee, Chan-Woo; Lee, Soo-Hun; Jeon, Yongho

    2014-04-01

    Laser scanning systems have been used for material processing tasks such as welding, cutting, marking, and drilling. However, applications have been limited by the small range of motion and slow speed of the focusing unit, which carries the focusing optics. To overcome these limitations, a dynamic focusing system with a long travel range and high speed is needed. In this study, a dynamic focusing unit for a laser scanning system with a voice coil motor (VCM) mechanism is proposed to enable fast speed and a wide focusing range. The VCM has finer precision and higher speed than conventional step motors and a longer travel range than earlier lead zirconium titanate actuators. The system has a hollow configuration to provide a laser beam path. This also makes it compact and transmission-free and gives it low inertia. The VCM's magnetics are modeled using a permeance model. Its design parameters are determined by optimization using the Broyden-Fletcher-Goldfarb-Shanno method and a sequential quadratic programming algorithm. After the VCM is designed, the dynamic focusing unit is fabricated and assembled. The permeance model is verified by a magnetic finite element method simulation tool, Maxwell 2D and 3D, and by measurement data from a gauss meter. The performance is verified experimentally. The results show a resolution of 0.2 μm and travel range of 16 mm. These are better than those of conventional focusing systems; therefore, this focusing unit can be applied to laser scanning systems for good machining capability.

  19. A novel voice coil motor-driven compliant micropositioning stage based on flexure mechanism

    Science.gov (United States)

    Shang, Jiangkun; Tian, Yanling; Li, Zheng; Wang, Fujun; Cai, Kunhai

    2015-09-01

    This paper presents a 2-degrees of freedom flexure-based micropositioning stage with a flexible decoupling mechanism. The stage is composed of an upper planar stage and four vertical support links to improve the out-of-plane stiffness. The moving platform is driven by two voice coil motors, and thus it has the capability of large working stroke. The upper stage is connected with the base through six double parallel four-bar linkages mechanisms, which are orthogonally arranged to implement the motion decoupling in the x and y directions. The vertical support links with serially connected hook joints are utilized to guarantee good planar motion with heavy-loads. The static stiffness and the dynamic resonant frequencies are obtained based on the theoretical analyses. Finite element analysis is used to investigate the characteristics of the developed stage. Experiments are carried out to validate the established models and the performance of the developed stage. It is noted that the developed stage has the capability of translational motion stroke of 1.8 mm and 1.78 mm in working axes. The maximum coupling errors in the x and y directions are 0.65% and 0.82%, respectively, and the motion resolution is less than 200 nm. The experimental results show that the developed stage has good capability for trajectory tracking.

  20. Design of voice coil motor dynamic focusing unit for a laser scanner

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Moon G.; Kim, Gaeun; Lee, Chan-Woo; Lee, Soo-Hun; Jeon, Yongho, E-mail: princaps@ajou.ac.kr [Department of Mechanical Engineering, Ajou University, San 5, Woncheon-dong, Yeongtong-gu, Suwon-si, Gyeonggi-do 443-749 (Korea, Republic of)

    2014-04-15

    Laser scanning systems have been used for material processing tasks such as welding, cutting, marking, and drilling. However, applications have been limited by the small range of motion and slow speed of the focusing unit, which carries the focusing optics. To overcome these limitations, a dynamic focusing system with a long travel range and high speed is needed. In this study, a dynamic focusing unit for a laser scanning system with a voice coil motor (VCM) mechanism is proposed to enable fast speed and a wide focusing range. The VCM has finer precision and higher speed than conventional step motors and a longer travel range than earlier lead zirconium titanate actuators. The system has a hollow configuration to provide a laser beam path. This also makes it compact and transmission-free and gives it low inertia. The VCM's magnetics are modeled using a permeance model. Its design parameters are determined by optimization using the Broyden–Fletcher–Goldfarb–Shanno method and a sequential quadratic programming algorithm. After the VCM is designed, the dynamic focusing unit is fabricated and assembled. The permeance model is verified by a magnetic finite element method simulation tool, Maxwell 2D and 3D, and by measurement data from a gauss meter. The performance is verified experimentally. The results show a resolution of 0.2 μm and travel range of 16 mm. These are better than those of conventional focusing systems; therefore, this focusing unit can be applied to laser scanning systems for good machining capability.

  1. Structure optimization of small-diameter polarization-maintaining photonic crystal fiber for mini coil of spaceborne miniature fiber-optic gyroscope.

    Science.gov (United States)

    Song, Ningfang; Cai, Wei; Song, Jingming; Jin, Jing; Wu, Chunxiao

    2015-11-20

    A small-diameter polarization-maintaining photonic crystal fiber (PM-PCF) for mini coils of spaceborne miniature fiber-optic gyroscopes is proposed in this paper. To ensure the strength of the small-diameter PM-PCF, a four-ring air holes structure is adopted. Using the full vector finite element method, dependence studies of modal field distribution, birefringence, and confinement loss on several key structure parameters are numerically investigated. The optimized parameter region is obtained. An optimized PM-PCF is fabricated, which can achieve similar to or even better optical properties than that of commercial PM-PCFs. The coating and cladding diameters of the optimized PM-PCF are 135 μm and 100 μm, respectively. Meanwhile, the optimized small-diameter PM-PCF shows a proof test level of 0.5%. The attenuation of the PM-PCF at 1550 nm is ∼2  dB/km. Typical volume of a mini coil wound with 300 m optimized PM-PCF is 5.9  cm3, which is decreased by ∼60% compared with a commercial PM-PCF coil of the same length. The bias stability of this coil is comparable with that of a conventional PMF coil of comparable length. Thus, the optimized small-diameter PM-PCF is suitable for mini coils of spaceborne miniature fiber-optic gyroscopes.

  2. Design and optimization of voice coil actuator for six degree of freedom active vibration isolation system using Halbach magnet array.

    Science.gov (United States)

    Kim, MyeongHyeon; Kim, Hyunchang; Gweon, Dae-Gab

    2012-10-01

    This paper describes the design, modeling, optimization, and validation of an active vibration isolation system using a voice coil motor. The active vibration isolating method was constructed with a passive isolator and an active isolator. A spring was used for passive isolating; an actuator was used for active isolating. The proposed active vibration isolation system (AVIS) can isolate disturbances for many kinds of instruments. Until now, developed AVIS were able to isolate a six degree-of-freedom disturbance effectively. This paper proposes the realization of such a six degree-of-freedom active vibration isolation system that can work as a bench top device for precision measuring machines such as atomic force microscope, scanning probe microscope, etc.

  3. A fault-tolerant triple-redundant voice coil motor for direct drive valves: Design, optimization, and experiment

    Institute of Scientific and Technical Information of China (English)

    Wu Shuai; Jiao Zongxia; Yan Liang; Yu Juntao; Chen Chin-Yin

    2013-01-01

    A direct drive actuator (DDA) with direct drive valves (DDVs) as the control device is an ideal solution for a flight actuation system.This paper presents a novel triple-redundant voice coil motor (TRVCM) used for redundant DDVs.The TRVCM features electrical/mechanical hybrid triple-redundancy by securing three stators along with three moving coils in the same frame.A permanent magnet (PM) Halbach array is employed in each redundant VCM to simplify the system structure.A back-to-back design between neighborly redundancies is adopted to decouple the magnetic flux linkage.The particle swarm optimization (PSO) method is implemented to optimize design parameters based on the analytical magnetic circuit model.The optimization objective function is defined as the acceleration capacity of the motor to achieve high dynamic performance.The optimal geometric parameters are verified with 3D magnetic field finite element analysis (FEA).A research prototype has been developed for experimental purpose.The experimental results of magnetic field density and force output show that the proposed TRVCM has great potential of applications in DDA systems.

  4. Longitudinal gradient coils with enhanced radial uniformity in restricted diameter: Single-current and multiple-current approaches

    Science.gov (United States)

    Romero, Javier A.; Domínguez, Gabriela A.; Anoardo, Esteban

    2017-03-01

    An important requirement for a gradient coil is that the uniformity of the generated magnetic field gradient should be maximal within the active volume of the coil. For a cylindrical geometry, the radial uniformity of the gradient turns critic, particularly in cases where the gradient-unit has to be designed to fit into the inner bore of a compact magnet of reduced dimensions, like those typically used in fast-field-cycling NMR. In this paper we present two practical solutions aimed to fulfill this requirement. We propose a matrix-inversion optimization algorithm based on the Biot-Savart law, that using a proper cost function, allows maximizing the uniformity of the gradient and power efficiency. The used methodology and the simulation code were validated in a single-current design, by comparing the computer simulated field map with the experimental data measured in a real prototype. After comparing the obtained results with the target field approach, a multiple-element coil driven by independent current sources is discussed, and a real prototype evaluated. Opposed equispaced independent windings are connected in pairs conforming an arrangement of independent anti-Helmholtz units. This last coil seizes 80% of its radial dimension with a gradient uniformity better than 5%. The design also provides an adaptable region of uniformity along with adjustable coil efficiency.

  5. Heating coil welding technique for connection of large-diameter PE pipes using universally applicable, flexible taped joints; Heizwendelschweissverfahren fuer die Verbindung von PE-Grossrohren mittels universal anwendbarer, flexibler Wickelmuffen

    Energy Technology Data Exchange (ETDEWEB)

    Baudrit, Benjamin; Kraus, Eduard; Heidemeyer, Peter; Bastian, Martin [Sueddeutsche Kunststoff-Zentrum, Wuerzburg (Germany); Kern, Juergen; Neufeld, Wjatscheslaw [Frank und Krah Wickelrohr GmbH, Woelfersheim (Germany)

    2011-07-01

    This research project (Heating coil welding technique for connection of large-diameter PE pipes using universally applicable, flexible taped joints) was carried out by SKZ (Sueddeutsches Kunststoff-Zentrum) in close coopearation with Messrs. Frank and Krah Wickelrohr GmbH with the intention to develop a high-quality, economically efficient joining process for large-diameter pipes. The technique is based on the new technology of heating coil joints which permits the use of any desired joint geometries at acceptable cost. The new technique was validated for joints up to a diameter of 1,000 mm. With the welding parameters calculated in the project, even larger diameter joints are possible in theory.

  6. 基于音圈电机的Stewart主动隔振平台设计%Design of Stewart Active Vibration Isolation Platform Based on Voice Coil Motor

    Institute of Scientific and Technical Information of China (English)

    吕俊超; 陈照波; 焦映厚; 刘文涛

    2013-01-01

    Stewart of Cubic form was used to design active vibration isolation platform, using voice coil motor (VCM)as actuators. Bars in this form of the Stewart platform was linearly independent of each other, so coupling effects can also be ignored. Six identical decentralized control strategy were used to control the Stewart platform, thus simplified and improved the reliability of the control system. Double -layer single -active bar was designed, using compound control method of feedforward-feedback. Adams/View and Matlab/Simulink co-simulation results show that the active control system has excellent vibration isolation effects.%以音圈电机作为作动器,采用“Cubic"构型的Stewart平台设计主动隔振系统.这种Stewart平台的各杆之间线性无关,耦合作用可以忽略不计,采用六路相同的控制方法对Stewart主动隔振平台进行分散控制,简化了控制系统,提高了系统的可靠性.通过分析设计了双层结构的单主动杆形式,并对其采用“前馈—反馈”的复合控制方法,并用六个单主动杆构成Stewart平台.对整个系统进行Adams/View和Matlab/Simulink的联合仿真,分析仿真结果可以看到所设计的主动控制系统具有良好的隔振效果.

  7. α/β coiled coils.

    Science.gov (United States)

    Hartmann, Marcus D; Mendler, Claudia T; Bassler, Jens; Karamichali, Ioanna; Ridderbusch, Oswin; Lupas, Andrei N; Hernandez Alvarez, Birte

    2016-01-15

    Coiled coils are the best-understood protein fold, as their backbone structure can uniquely be described by parametric equations. This level of understanding has allowed their manipulation in unprecedented detail. They do not seem a likely source of surprises, yet we describe here the unexpected formation of a new type of fiber by the simple insertion of two or six residues into the underlying heptad repeat of a parallel, trimeric coiled coil. These insertions strain the supercoil to the breaking point, causing the local formation of short β-strands, which move the path of the chain by 120° around the trimer axis. The result is an α/β coiled coil, which retains only one backbone hydrogen bond per repeat unit from the parent coiled coil. Our results show that a substantially novel backbone structure is possible within the allowed regions of the Ramachandran space with only minor mutations to a known fold.

  8. Feeling voices.

    Directory of Open Access Journals (Sweden)

    Paolo Ammirante

    Full Text Available Two experiments investigated deaf individuals' ability to discriminate between same-sex talkers based on vibrotactile stimulation alone. Nineteen participants made same/different judgments on pairs of utterances presented to the lower back through voice coils embedded in a conforming chair. Discrimination of stimuli matched for F0, duration, and perceived magnitude was successful for pairs of spoken sentences in Experiment 1 (median percent correct = 83% and pairs of vowel utterances in Experiment 2 (median percent correct = 75%. Greater difference in spectral tilt between "different" pairs strongly predicted their discriminability in both experiments. The current findings support the hypothesis that discrimination of complex vibrotactile stimuli involves the cortical integration of spectral information filtered through frequency-tuned skin receptors.

  9. Needleless Electrospinning of Uniform Nanofibers Using Spiral Coil Spinnerets

    Directory of Open Access Journals (Sweden)

    Xin Wang

    2012-01-01

    Full Text Available Polyvinyl alcohol nanofibers were prepared by a needleless electrospinning technique using a rotating spiral wire coil as spinneret. The influences of coil dimension (e.g., coil length, coil diameter, spiral distance, and wire diameter and operating parameters (e.g., applied voltage and spinning distance on electrospinning process, nanofiber diameter, and fiber productivity were examined. It was found that the coil dimension had a considerable influence on the nanofiber production rate, but minor effect on the fiber diameter. The fiber production rate increased with the increased coil length or coil diameter, or the reduced spiral distance or wire diameter. Higher applied voltage or shorter collecting distance also improved the fiber production rate but had little influence on the fiber diameter. Compared with the conventional needle electrospinning, the coil electrospinning produced finer fibers with a narrower diameter distribution. A finite element method was used to analyze the electric field on the coil surface and in electrospinning zone. It was revealed that the high electric field intensity was concentrated on the coil surface, and the intensity was highly dependent on the coil dimension, which can be used to explain the electrospinning performances of coils. In addition, PAN nanofibers were prepared using the same needleless electrospinning technique to verify the improvement in productivity.

  10. 基于改进Preisach模型的音圈电机复杂迟滞建模%Complex hysteresis modeling for a voice coil motor based on improved preisach model

    Institute of Scientific and Technical Information of China (English)

    党选举; 梁卫; 姜辉

    2012-01-01

    针对音圈电机在高频响、高速、高加速度运动时存在的一种特殊复杂迟滞特性,提出一种改进的Preisach迟滞与RBF神经网络相结合的动态迟滞混合模型.采用逐次逼近的思想,第一级通过构造一个改进型Preisach模型,引入非单调信息,使其输出具有非单调迟滞特性.第二级采用动态RBF神经网络对第一级输出的相位和幅值进行补偿,实现对音圈电机实际输出的高精度逼近.基于实测数据的仿真实验结果表明,所提出的模型对一般迟滞和非单调复杂迟滞的建模都是有效的.与动态神经网络建模相比,具有更高的模型精度.%A special complex hysteresis characteristic exists in a voice coil motor (VCM) under high-frequency response, high-speed and high-acceleration motion making the system performance go worse. In order to achieve a precise positioning control for a VCM, a hybrid hysteresis model consisting of an improved Preisach model and a RBF dynamic neural network was proposed. In the improved Preisach model, non-monotonic information was introduced for describing the non-monotonic hysteresis behavior. Based on the former, a dynamic radial basis function (RBF) neural network was used to compensate the amplitude and phase error between the dynamic Preisach output and the real VCM hysteresis for a higher accuracy. Finally, the simulation results based on the measured data showed that the proposed hybrid model is effective not only for general hysteresis modeling but also for non-monotonic complex hysteresis modeling. Comparing with the dynamic neural network modeling, this hybrid model had a higher accuracy.

  11. Solid catalytic growth mechanism of micro-coiled carbon fibers

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Micro-coiled carbon fibers were prepared by catalytic pyrolysisof acetylene with nano-sized nickel powder catalyst using the substrate method. The morphology of micro-coiled carbon fibers was observed through field emission scanning electron microscopy. It was found that the fiber and coil diameter of the obtained micro-coiled carbon fibers is about 500—600 nm and 4—5 μm, respectively. Most of the micro-coiled carbon fibers obtained were regular double carbon coils, but a few irregular ones were also observed. On the basis of the experimental observation, a solid catalytic growth mechanism of micro-coiled carbon fibers was proposed.

  12. Voice Disorders

    Science.gov (United States)

    Voice is the sound made by air passing from your lungs through your larynx, or voice box. In your larynx are your vocal cords, ... to make sound. For most of us, our voices play a big part in who we are, ...

  13. Every Voice

    Science.gov (United States)

    Patrick, Penny

    2008-01-01

    This article discusses how the author develops an approach that allows her students, who are part of the marginalized population, to learn the power of their own voices--not just their writing voices, but their oral voices as well. The author calls it "TWIST": Thoughts, Writing folder, Inquiring mind, Supplies, and Teamwork. It is where…

  14. Every Voice

    Science.gov (United States)

    Patrick, Penny

    2008-01-01

    This article discusses how the author develops an approach that allows her students, who are part of the marginalized population, to learn the power of their own voices--not just their writing voices, but their oral voices as well. The author calls it "TWIST": Thoughts, Writing folder, Inquiring mind, Supplies, and Teamwork. It is where…

  15. Voice restoration

    NARCIS (Netherlands)

    Hilgers, F.J.M.; Balm, A.J.M.; van den Brekel, M.W.M.; Tan, I.B.; Remacle, M.; Eckel, H.E.

    2010-01-01

    Surgical prosthetic voice restoration is the best possible option for patients to regain oral communication after total laryngectomy. It is considered to be the present "gold standard" for voice rehabilitation of laryngectomized individuals. Surgical prosthetic voice restoration, in essence, is alwa

  16. Coiled-Coil Design: Updated and Upgraded.

    Science.gov (United States)

    Woolfson, Derek N

    2017-01-01

    α-Helical coiled coils are ubiquitous protein-folding and protein-interaction domains in which two or more α-helical chains come together to form bundles. Through a combination of bioinformatics analysis of many thousands of natural coiled-coil sequences and structures, plus empirical protein engineering and design studies, there is now a deep understanding of the sequence-to-structure relationships for this class of protein architecture. This has led to considerable success in rational design and what might be termed in biro de novo design of simple coiled coils, which include homo- and hetero-meric parallel dimers, trimers and tetramers. In turn, these provide a toolkit for directing the assembly of both natural proteins and more complex designs in protein engineering, materials science and synthetic biology. Moving on, the increased and improved use of computational design is allowing access to coiled-coil structures that are rare or even not observed in nature, for example α-helical barrels, which comprise five or more α-helices and have central channels into which different functions may be ported. This chapter reviews all of these advances, outlining improvements in our knowledge of the fundamentals of coiled-coil folding and assembly, and highlighting new coiled coil-based materials and applications that this new understanding is opening up. Despite considerable progress, however, challenges remain in coiled-coil design, and the next decade promises to be as productive and exciting as the last.

  17. Fabrication of the planar coils for WENDELSTEIN 7-X

    Energy Technology Data Exchange (ETDEWEB)

    Viebke, H. [Max-Planck-Institut fuer Plasmaphysik, Greifswald Branch, Euratom Association, Wendelsteinstrasse 1, D-17491 Greifswald (Germany)]. E-mail: holger.viebke@ipp.mpg.de; Rummel, Th. [Max-Planck-Institut fuer Plasmaphysik, Greifswald Branch, Euratom Association, Wendelsteinstrasse 1, D-17491 Greifswald (Germany); Risse, K. [Max-Planck-Institut fuer Plasmaphysik, Greifswald Branch, Euratom Association, Wendelsteinstrasse 1, D-17491 Greifswald (Germany); Schroeder, R. [Max-Planck-Institut fuer Plasmaphysik, Greifswald Branch, Euratom Association, Wendelsteinstrasse 1, D-17491 Greifswald (Germany); Winter, R. [Tesla Engineering Ltd., Water Lane, Storrington, Sussex RH20 3EA (United Kingdom)

    2005-11-15

    WENDELSTEIN 7-X (W7-X) is a superconducting stellarator, which uses 50 non-planar coils for the main field and 20 planar coils to modify the magnetic configuration. The planar coils are cut into two differently shaped types and designed for 3 T on the plasma axis. A planar coil has an outer diameter of around 4 m. The main elements of planar coils are the winding package, the coil case, the interlayer joints to connect the double layers, and the case cooling with instrumentation. The connection to the coil support structure is performed through forged blocks welded to the casing and bolts. The manufacturing is being performed with a high accuracy to maintain the required symmetry of the magnetic configuration of W7-X. Prior to dispatch the coils pass a works acceptance test at Tesla. After production, all coils are subjected to a functional test at cryogenic temperatures at the Low Temperature Laboratory of CEA at Saclay.

  18. Designing Stable Antiparallel Coiled Coil Dimers

    Institute of Scientific and Technical Information of China (English)

    曾宪纲; 周海梦

    2001-01-01

    The history of antiparallel coiled coil dimer design is briefly reviewed and the main principles governing the successful designs are explained. They include analysis of the inter-subunit electrostatic repulsion for determining partners for dimerization and of the buried polar interaction for determining the relative orientation of the partners. A theory is proposed to explain the lack of antiparallel coiled coil homodimers in nature.

  19. MEMS switch integrated radio frequency coils and arrays for magnetic resonance imaging

    Science.gov (United States)

    Bulumulla, S. B.; Park, K. J.; Fiveland, E.; Iannotti, J.; Robb, F.

    2017-02-01

    Surface coils are widely used in magnetic resonance imaging and spectroscopy. While smaller diameter coils produce higher signal to noise ratio (SNR) closer to the coil, imaging larger fields of view or greater distance into the sample requires a larger overall size array or, in the case of a channel count limited system, larger diameter coils. In this work, we consider reconfiguring the geometry of coils and coil arrays such that the same coil or coil array may be used in multiple field of view imaging. A custom designed microelectromechanical systems switch, compatible with magnetic resonance imaging, is used to switch in/out conductive sections and components to reconfigure coils. The switch does not degrade the SNR and can be opened/closed in 10 μ s, leading to rapid reconfiguration. Results from a single coil, configurable between small/large configurations, and a two-coil phased array, configurable between spine/torso modes, are presented.

  20. Coil Welding Aid

    Science.gov (United States)

    Wiesenbach, W. T.; Clark, M. C.

    1983-01-01

    Positioner holds coil inside cylinder during tack welding. Welding aid spaces turns of coil inside cylinder and applies contact pressure while coil is tack-welded to cylinder. Device facilitates fabrication of heat exchangers and other structures by eliminating hand-positioning and clamping of individual coil turns.

  1. Starfire poloidal coil systems

    Energy Technology Data Exchange (ETDEWEB)

    Evans, K. Jr.; Kim, S.H.; Turner, L.R.; Wang, S.T.

    1980-01-01

    The poloidal coils for STARFIRE consists of three systems: (1) equilibrium field (EF) coils; (2) ohmic heating (OH) coils; and (3) correction field (CF) coils. The EF coils are superconducting and lie outside the toroidal field (TF) coils. These coils provide the bulk of the equilibrium field necessary to keep the plasma positioned in the vacuum chamber with the desired cross sectional shape and pressure and current distributions. Having these coils outside of the TF coils requires that they have a larger stored energy and larger currents but eases the assembly, maintenance, and reliability of the coils. The STARFIRE OH system is relatively small compared to tokamaks in which the current is entirely ohmically driven. It is designed to provide sufficient flux in the early startup to raise the plasma current to the point (1 to 2 MA) where the rf current drive can take over.

  2. MRI surface-coil pair with strong inductive coupling.

    Science.gov (United States)

    Mett, Richard R; Sidabras, Jason W; Hyde, James S

    2016-12-01

    A novel inductively coupled coil pair was used to obtain magnetic resonance phantom images. Rationale for using such a structure is described in R. R. Mett et al. [Rev. Sci. Instrum. 87, 084703 (2016)]. The original rationale was to increase the Q-value of a small diameter surface coil in order to achieve dominant loading by the sample. A significant improvement in the vector reception field (VRF) is also seen. The coil assembly consists of a 3-turn 10 mm tall meta-metallic self-resonant spiral (SRS) of inner diameter 10.4 mm and outer diameter 15.1 mm and a single-loop equalization coil of 25 mm diameter and 2 mm tall. The low-frequency parallel mode was used in which the rf currents on each coil produce magnetic fields that add constructively. The SRS coil assembly was fabricated and data were collected using a tissue-equivalent 30% polyacrylamide phantom. The large inductive coupling of the coils produces phase-coherency of the rf currents and magnetic fields. Finite-element simulations indicate that the VRF of the coil pair is about 4.4 times larger than for a single-loop coil of 15 mm diameter. The mutual coupling between coils influences the current ratio between the coils, which in turn influences the VRF and the signal-to-noise ratio (SNR). Data on a tissue-equivalent phantom at 9.4 T show a total SNR increase of 8.8 over the 15 mm loop averaged over a 25 mm depth and diameter. The experimental results are shown to be consistent with the magnetic resonance theory of the emf induced by spins in a coil, the theory of inductively coupled resonant circuits, and the superposition principle. The methods are general for magnetic resonance and other types of signal detection and can be used over a wide range of operating frequencies.

  3. Numerical and experimental analysis of harmonic distortion in a moving-coil loudspeaker

    Science.gov (United States)

    Chang, Chun; Wang, Chi-Chang; Shiah, Y. C.; Huang, Jin H.

    2013-07-01

    The nonlinear effect of a moving-coil loudspeaker, originating from its magnetic coupling factor and the system's stiffness, presents a significant impact on the sound quality. For improving the sound quality, this article proposes an approach to reduce the total harmonic distortion (THD) by adjusting the initial position of its voice-coil. First, a mathematical model involving the nonlinearities of force factor, mechanical stiffness, and inductance of voice coil is constructed and then solved using a novel algorithm called the parameter spline difference method (PSD). In the course of pursuing reduction of the corresponding THD of a typical moving-coil loudspeaker, the model was used to analyze the nonlinearity of the THD, revealing itself as a nonlinear function of force factor, the system's stiffness and inductance of voice coil. For various initial positions of the voice-coil, the coupled nonlinear differential equations were solved using the PSD to yield corresponding sound pressure level and THD. To our satisfaction, the loudspeaker driver with its voice-coil optimally tuned for the initial position turns out to have a THD reduction of 10%, which is also consistent with our experimental observations.

  4. Protective link for superconducting coil

    Science.gov (United States)

    Umans, Stephen D.

    2009-12-08

    A superconducting coil system includes a superconducting coil and a protective link of superconducting material coupled to the superconducting coil. A rotating machine includes first and second coils and a protective link of superconducting material. The second coil is operable to rotate with respect to the first coil. One of the first and second coils is a superconducting coil. The protective link is coupled to the superconducting coil.

  5. Keeping Your Voice Healthy

    Science.gov (United States)

    ... Find an ENT Doctor Near You Keeping Your Voice Healthy Keeping Your Voice Healthy Patient Health Information ... heavily voice-related. Key Steps for Keeping Your Voice Healthy Drink plenty of water. Moisture is good ...

  6. High-resolution MR imaging of triangular fibrocartilage complex (TFCC): comparison of microscopy coils and a conventional small surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Yoshioka, Hiroshi [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Department of Radiology, Brigham and Women' s Hospital, 75 Francis Street, 02115, Boston, MA (United States); Ueno, Teruko; Itai, Yuji [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Tanaka, Toshikazu [Department of Orthopedic Surgery, Tsukuba Kinen Hospital, Tsukuba (Japan); Shindo, Masashi [Tsukuba University Hospital, Tsukuba (Japan)

    2003-10-01

    To compare MR images of the triangular fibrocartilage complex (TFCC) using microscopy coils with those using a conventional surface coil qualitatively and quantitatively. Proton density-weighted images and T2*-weighted images of the TFCC from ten normal volunteers were obtained with a conventional surface coil (C4 coil; 80 mm in diameter), a 47-mm microscopy surface coil and a 23-mm microscopy surface coil at 1.5 T. Qualitative image analysis of MR images with three coils was performed by two radiologists who assigned one of five numerical scores (0, nonvisualization; 1, poor; 2, average; 3, good; 4, excellent) for five TFCC components, which were disc proper, triangular ligament, meniscus homologue, ulnotriquetral and ulnolunate ligament. Quantitative analysis included the signal-to-noise ratio (S/N) of the disc proper of TFCC, the lunate cartilage, the lunate bone and the contrast-noise-ratio (C/N) between articular cartilage and disc proper or bone marrow were measured. All structures show higher scores qualitatively on MR with microscopy coils than those with a C4 coil, and the difference was significant with the exception of the ulnolunate ligament. MR with microscopy coils showed significantly higher S/N values than those with a conventional surface coil (P<0.05 to P<0.001). T2*-weighted images using microscopy coils showed significantly higher cartilage-disc proper C/N and cartilage-bone marrow C/N (P<0.01 to P<0.001). On proton density-weighted images, the C/N between cartilage and disc proper with two microscopy coils was significantly higher (P<0.01) than that with a conventional coil. High-resolution MR images of the normal wrist using microscopy coils were superior to those using a conventional surface coil qualitatively and quantitatively. High-resolution MR imaging with a microscopy coil would be a promising method to diagnose TFCC lesions. (orig.)

  7. Starch gelatinization in coiled heaters.

    Science.gov (United States)

    Kelder, J D H; Ptasinski, K J; Kerkhof, P J A M

    2004-01-01

    A gelatinizing model food derived from a 5% w/w cross-linked waxy maize starch suspension was simulated in coiled heaters to assess the impact of centrifugal forces on flow and heat transfer. For four coil diameters (D = 0.25, 1, 2.5, and infinity m) and three flow rates (w = 0.5, 1, and 2 m/s), heat transfer, viscous development, and the severity of channeling were evaluated. Increasing curvature proved to suppress channeling as a result of more uniform heating and gelatinization. The maximum attainable viscosity was also higher, implying a lower starch consumption for a target viscosity. Higher flow rates necessitated longer heaters, and the maximum viscosity decreased. Moderate product velocities are therefore recommended.

  8. ATLAS-Lowering the first Barrel Toroid coil

    CERN Multimedia

    CERN Audiovisual Unit

    2004-01-01

    Cranes lowered the first of ATLAS's eight Barrel Toroid coils into the cavern. The part is 25 meters long and the cranes had to hold the 100 tonne coil at a sharp angle while it passed through the 18-meter diameter vertical shaft into the cavern. Then they laid the magnet to a horizontal robust platform. Images from Camera 2

  9. ATLAS-Lowering the first Barrel Toroid coil

    CERN Multimedia

    2004-01-01

    Cranes lowered the first of ATLAS's eight Barrel Toroid coils into the cavern. The part is 25 metres long and the cranes had to hold the 100 tonne coil at a sharp angle while it passed through the 18-metre diameter vertical shaft into the cavern. Then they laid the magnet to a horisontal robust platform. Images from Camera 1

  10. Dual coil ignition system

    Energy Technology Data Exchange (ETDEWEB)

    Huberts, Garlan J.; Qu, Qiuping; Czekala, Michael Damian

    2017-03-28

    A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding.

  11. Foldable micro coils for a transponder system measuring intraocular pressure

    Energy Technology Data Exchange (ETDEWEB)

    Ullerich, S.; Schnakenberg, U. [Technische Hochschule Aachen (Germany). Inst. of Materials in Electrical Engineering 1; Mokwa, W. [Technische Hochschule Aachen (Germany). Inst. of Materials in Electrical Engineering 1]|[Fraunhofer Inst. of Microelectronic Circuits and Systems, Duisburg (Germany); Boegel, G. vom [Fraunhofer Inst. of Microelectronic Circuits and Systems, Duisburg (Germany)

    2001-07-01

    A foldable transponder system consisting of a chip and a micro coil for measuring intraocular pressure continuously is presented. The system will be integrated in the haptic of a soft artificial intraocular lens. Calculations of planar micro coils with 6 mm and 10.3 mm in diameter show the limits for planar coils with an outer diameter of 6 mm. For the realisation of the transponder system a 20 {mu}m thick coil with an outer diameter of 10.3 mm, an inner diameter of 7.7 mm, 16 turns and a gap of 20 {mu}m between the windings was selected. Measurements show a good agreement between calculated and measured values. Wireless pressure measurements were carried out showing a linear behaviour of the output signal with respect to the applied pressure. (orig.)

  12. Magnetomotive forming for precision sizing and joining of large-diameter tubes

    Science.gov (United States)

    Bennight, J. D.; Schwinghamer, R. J.

    1969-01-01

    Portable electromagnetic coil enables high precision expansion or constriction and joining of large diameter metal tubes. A nonconducting mandrel or forming die is used on the side of the tubes wall opposite the coil. The coil is insulated from the tube by a thin plastic sleeve.

  13. Embroidered Coils for Magnetic Resonance Sensors

    Directory of Open Access Journals (Sweden)

    Michael I. Newton

    2013-04-01

    Full Text Available Magnetic resonance imaging is a widely used technique for medical and materials imaging. Even though the objects being imaged are often irregularly shaped, suitable coils permitting the measurement of the radio-frequency signal in these systems are usually made of solid copper. One problem often encountered is how to ensure the coils are both in close proximity and conformal to the object being imaged. Whilst embroidered conductive threads have previously been used as antennae in mobile telecommunications applications, they have not previously been reported for use within magnetic resonance. In this paper we show that an embroidered single loop coil can be used in a commercial unilateral nuclear magnetic resonance system as an alternative to a solid copper. Data is presented showing the determination of both longitudinal (T1 and effective transverse (T2eff relaxation times for a flat fabric coil and the same coil conformed to an 8 cm diameter cylinder. We thereby demonstrate the principles required for the wider use of fabric based conformal coils within nuclear magnetic resonance and magnetic resonance imaging.

  14. Experimental Study of Free Convection in Coiled Tube Heat Exchanger

    Directory of Open Access Journals (Sweden)

    Harith Mohammed

    2013-05-01

    Full Text Available An experimental study has been conducted on steady-state natural convection heat transfer from helical coil tubes in vertical orientation. Water was used as a bath liquid without any mixing and cold water was used as a coolant fluid. A straight copper tube of 6 mm ID, 8 mm OD and 3 m length was bend to fabricate the helical coil. Four coils are used in this experiment has different curvature ratios and pitches. The data were correlated using tube diameter as the characteristic length. The results show that the overall heat transfer coefficient and Nusselt number increase when the flow rate of coolant and curvature ratio increase. The effect of coil pitch was investigated and the results show that when of the coil pitch (angle of inclination increases Nusselt number increase. A correlation was presented to calculate the outside average Nusselt number of coil.

  15. Coil system for plasmoid thruster

    Science.gov (United States)

    Eskridge, Richard H. (Inventor); Lee, Michael H. (Inventor); Martin, Adam K. (Inventor); Fimognari, Peter J. (Inventor)

    2010-01-01

    A coil system for a plasmoid thruster includes a bias coil, a drive coil and field coils. The bias and drive coils are interleaved with one another as they are helically wound about a conical region. A first field coil defines a first passage at one end of the conical region, and is connected in series with the bias coil. A second field coil defines a second passage at an opposing end of the conical region, and is connected in series with the bias coil.

  16. Estimation and measurement of flat or solenoidal coil inductance for radiofrequency NMR coil design.

    Science.gov (United States)

    Rainey, Jan K; DeVries, Jeffrey S; Sykes, Brian D

    2007-07-01

    The inductance of a radiofrequency coil determines its compatibility with a given NMR probe circuit. However, calculation (or estimation) of inductance for radiofrequency coils of dimensions suitable for use in an NMR probe is not trivial, particularly for flat-coils. A comparison of a number of formulae for calculation of inductance is presented through the use of a straightforward inductance measurement circuit. This technique relies upon instrumentation available in many NMR laboratories rather than upon more expensive and specialized instrumentation often utilized in the literature. Inductance estimation methods are suggested and validated for both flat-coils and solenoids. These have proven very useful for fabrication of a number of new coils in our laboratory for use in static solid-state NMR probes operating at (1)H frequencies of 300 and 600MHz. Solenoidal coils with very similar measured and estimated inductances having inner diameters from 1 to 5mm are directly compared as an example of the practical application of inductance estimation for interchange of coils within an existing solid-state NMR probe.

  17. Research and development of MRI surface coil for TMJ MR imaging; Modulated Helmholtz surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Kukimoto, Yoshiaki; Kukimoto, Kyoko (Kameda General Hospital, Kamogawa, Chiba (Japan)); Shirakawa, Toyomi

    1989-12-01

    Internal derangements of the temporomandibular joint (TMJ) are a major cause of jaw pain and dysfunction as well as other related clinical symptoms. TMJ diagnosis is the abnormal position and appearance of the disk. Most X-ray-based methods are useful for evaluating bony abnormalities, but their reduced soft-tissue contrast often makes the diagnostic evaluation of TMJ disorders difficult. Magnetic resonance (MR) imaging is a very recent addition to the medical diagnostic of TMJ diseases. MR imaging can produce high-quality tomographic images of greater soft-tissue contrast without ionizing radiation or known biological hazards. MR system was circular type Simens Magnetom 1.5 tesla. Display matrix was 256x256. A Modulated Helmholtz type coil of 17 cm in diameter was developed in Kameda General Hospital in order to increase signal to noise ratio in the area of bilateral TMJs. The distance between two coils was 16-20 cm. The head was placed in supine position in the center of two surface coils. A Modulated Helmholtz type coil: 1. Modulated Helmholtz type coil was used as an emitter and a receiver. 2. Modulated Helmholtz type coil had a pair of 17 cm coils, which were movable according to head width of each patient. 3. MR imaging of bilateral TMJs was taken at once because of no necessity to reset a surfacecoil. 4. It was easy to set positioning of the head. (author).

  18. Liquid rope coiling

    NARCIS (Netherlands)

    N.M. Ribe; M. Habibi; D. Bonn

    2012-01-01

    A thin stream or rope of viscous fluid falling from a sufficient height onto a surface forms a steadily rotating helical coil. Tabletop laboratory experiments in combination with a numerical model for slender liquid ropes reveal that finite-amplitude coiling can occur in four distinct regimes (visco

  19. Optimal Bitter Coil Solenoid

    CERN Document Server

    Kobelev, V

    2016-01-01

    Bitter coil is an electromagnet used for the generation of exceptionally strong magnetic fields. The upper bound of magnet flux density is restricted by several factors. One principal restriction is the high stresses due to Lorentz forces in the coil. The Lorentz forces generate the distributed body force, which acts as the pressure of magnetic field. The common radial thickness profile of the Bitter coil is constant. In this paper the possibility of optimization by means of non-constant radial thickness profile of the Bitter coil is studied. The close form expression for optimal thickness profile is obtained. Both designs are compared and the considerable improvement of magnetic flux density is demonstrated. Moreover, the optimal design improves the shape of cooling channels. Namely, the highest cross-section of cooling channel is at the most thermally loaded inner surface of the coil.

  20. MFTF test coil construction and performance

    Energy Technology Data Exchange (ETDEWEB)

    Cornish, D.N.; Zbasnik, J.P.; Leber, R.L.; Hirzel, D.G.; Johnston, J.E.; Rosdahl, A.R.

    1978-09-25

    A solenoid coil, 105 cm inside the 167 cm outside diameter, has been constructed and tested to study the performance of the stabilized Nb--Ti conductor to be used in the Mirror Fusion Test Facility (MFTF) being built at Lawrence Livermore Laboratory. The insulation system of the test coil is identical to that envisioned for MFTF. Cold-weld joints were made in the conductor at the start and finish of each layer; heaters were fitted to some of these joints and also to the conductor at various locations in the winding. This paper gives details of the construction of the coil and the results of the tests carried out to determine its propagation and recovery characteristics.

  1. Commercial applications for COIL

    Science.gov (United States)

    Solomon, Wayne C.; Carroll, David L.; King, D. M.; Fockler, L. A.; Stromberg, D. S.; Sexauer, M.; Milmoe, A.; Sentman, Lee H.

    2000-01-01

    The chemical oxygen-iodine laser (COIL) is a high power, fiber deliverable tool, which can be used for a number of different industrial applications. COIL is of particular interest because of its short fiber deliverable wavelength, high scaleable continuous wave power, and excellent material interaction properties. In past research the University of Illinois at Urbana-Champaign identified and decommissioning and decontamination (DD) of nuclear facilities as a primary focus for COIL technology. DD will be a major challenge in the coming decades. The use of a robotically driven fiber delivered cutting/ablation tool in contaminated areas promises to lower risks to workers for the DD mission. Further, the high cutting speed of COIL will significantly reduce the time required to cut contaminated equipment, reducing costs. The high power of COIL will permit the dismantling of thick stacks of piping and equipment as well as reactor vessels. COIL is very promising for the removal of material from contaminated surfaces, perhaps to depths thicker than an inch. Laser cutting and ablation minimizes dust and fumes, which reduces the required number of high efficiency particulate accumulator filters, thus reducing costly waste disposal. Other potential industrial applications for COIL are shipbuilding, automotive manufacturing, heavy machinery manufacturing, tasks requiring underwater cutting or welding, and there appear to be very promising applications for high powers lasers in the oil industry.

  2. The Whole Elephant: A Synoptic View of Liquid Rope Coiling

    Science.gov (United States)

    Ribe, Neil

    2016-11-01

    Liquid rope coiling is the instability that occurs when e.g. a thin stream of honey is poured onto toast. While we now have a fine-grained understanding of each of the four principal coiling modes (viscous, gravitational, inertio-gravitational and inertial), we still lack a global view of how the modes cohere to form a larger whole. Using a numerical continuation procedure, I determine how the dimensionless coiling frequency depends on the dimensionless fall height and flow rate, for several values of the dimensionless nozzle diameter. Starting with the onset of coiling, I propose a purely geometrical definition of the critical surface between coiling and no coiling as the locus of points where the radius a1 of the rope at the contact point is just equal to the coil radius R. Coiling with a1 > R is impossible because the rope would intersect itself. I characterize the asymptotic limits of the critical surface as well as the structure of the supercritical volume inside that surface. The procedure reveals a new mode of coiling onset that has not yet been identified.

  3. A periodic table of coiled-coil protein structures.

    Science.gov (United States)

    Moutevelis, Efrosini; Woolfson, Derek N

    2009-01-23

    Coiled coils are protein structure domains with two or more alpha-helices packed together via interlacing of side chains known as knob-into-hole packing. We analysed and classified a large set of coiled-coil structures using a combination of automated and manual methods. This led to a systematic classification that we termed a "periodic table of coiled coils," which we have made available at http://coiledcoils.chm.bris.ac.uk/ccplus/search/periodic_table. In this table, coiled-coil assemblies are arranged in columns with increasing numbers of alpha-helices and in rows of increased complexity. The table provides a framework for understanding possibilities in and limits on coiled-coil structures and a basis for future prediction, engineering and design studies.

  4. Characteristics of aerodynamic sound sources generated by coiled wires in a uniform air-flow

    Science.gov (United States)

    Matsumoto, H.; Nishida, K.; Saitoh, K.

    2003-11-01

    This study deals experimentally with aerodynamic sounds generated by coiled wires in a uniform air-flow. The coiled wire is a model of the hair dryer's heater. In the experiment, the effects of the coil diameter D, wire diameter d and coil spacing s of the coiled wire on the aerodynamic sound have been clarified. The results of frequency analyses of the aerodynamic sounds show that an Aeolian sound is generated by the coiled wire, when s/d is larger than 1. Also the peak frequencies of Aeolian sounds generated by the coiled wires are higher than the ones generated by a straight cylinder having the same diameter d. To clarify the characteristics of the aerodynamic sound sources, the directivity of the aerodynamic sound generated by the coiled wire has been examined, and the coherent function between the velocity fluctuation around the coiled wire and the aerodynamic sound has been calculated. Moreover, the band overall value of coherent output power between the sound and the velocity fluctuations has been calculated. This method has clarified the sound source region of the Aeolian sound generated by the coiled wire. These results show that the Aeolian sound is generated by the arc part of the coiled wire, which is located in the upstream side of the air-flow.

  5. LHCb magnet coils arrive

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Each of the two coils for the LHCb magnet comprises 15 individual monolayer 'pancakes' of identical trapezoidal racetrack shape, and is bent at 45 degrees on the two transverse sides. Each pancake consists of eight turns of conductor, wound from a single length (approx. 290 m) of extruded aluminium. The coils have arrived at CERN; one of them is seen here being unloaded above the LHCb experimental cavern.

  6. Coiling of yield stress fluids

    NARCIS (Netherlands)

    Y. Rahmani; M. Habibi; A. Javadi; D. Bonn

    2011-01-01

    We present an experimental investigation of the coiling of a filament of a yield stress fluid falling on a solid surface. We use two kinds of yield stress fluids, shaving foam and hair gel, and show that the coiling of the foam is similar to the coiling of an elastic rope. Two regimes of coiling (el

  7. Speaking and Nonspeaking Voice Professionals: Who Has the Better Voice?

    Science.gov (United States)

    Chitguppi, Chandala; Raj, Anoop; Meher, Ravi; Rathore, P K

    2017-04-18

    Voice professionals can be classified into two major subgroups: the primarily speaking and the primarily nonspeaking voice professionals. Nonspeaking voice professionals mainly include singers, whereas speaking voice professionals include the rest of the voice professionals. Although both of these groups have high vocal demands, it is currently unknown whether both groups show similar voice changes after their daily voice use. Comparison of these two subgroups of voice professionals has never been done before. This study aimed to compare the speaking voice of speaking and nonspeaking voice professionals with no obvious vocal fold pathology or voice-related complaints on the day of assessment. After obtaining relevant voice-related history, voice analysis and videostroboscopy were performed in 50 speaking and 50 nonspeaking voice professionals. Speaking voice professionals showed significantly higher incidence of voice-related complaints as compared with nonspeaking voice professionals. Voice analysis revealed that most acoustic parameters including fundamental frequency, jitter percent, and harmonic-to-noise ratio were significantly higher in speaking voice professionals, whereas videostroboscopy did not show any significant difference between the two groups. This is the first study of its kind to analyze the effect of daily voice use in the two subgroups of voice professionals with no obvious vocal fold pathology. We conclude that voice professionals should not be considered as a homogeneous group. The detrimental effects of excessive voice use were observed to occur more significantly in speaking voice professionals than in nonspeaking voice professionals. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  8. Linear Rogowski coil

    Science.gov (United States)

    Nassisi, V.; Delle Side, D.

    2017-02-01

    Nowadays, the employment and development of fast current pulses require sophisticated systems to perform measurements. Rogowski coils are used to diagnose cylindrical shaped beams; therefore, they are designed and built with a toroidal structure. Recently, to perform experiments of radiofrequency biophysical stresses, flat transmission lines have been developed. Therefore, in this work we developed a linear Rogowski coil to detect current pulses inside flat conductors. The system is first approached by means of transmission line theory. We found that, if the pulse width to be diagnosed is comparable with the propagation time of the signal in the detector, it is necessary to impose a uniform current as input pulse, or to use short coils. We further analysed the effect of the resistance of the coil and the influence of its magnetic properties. As a result, the device we developed is able to record pulses lasting for some hundreds of nanoseconds, depending on the inductance, load impedance, and resistance of the coil. Furthermore, its response is characterized by a sub-nanosecond rise time (˜100 ps). The attenuation coefficient depends mainly on the turn number of the coil, while the fidelity of the response depends both on the magnetic core characteristics and on the current distribution along the plane conductors.

  9. High-quality Critical Heat Flux in Horizontally Coiled Tubes

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    An investigation on the high-quality dryout in two electrically heated coiled tubes with horizontally helix axes is reported.The temperature profiles both along the tube and around the circumference are measured.and it is found that the temperature profiles around the circumference are not identical for the corss-sections at different parts of the coil.The “local condition hypothesis” seems applicable under present conditions,and the critical heat flux qcr decreases with increasing critical quality xcr.The CHF increases as mass velocity and ratio of tube diameter to coil diameter(d/D) increases,and it seems not to be affected hby the system pressure.The CHF is larger with coils than that with straight tubes,and the difference increases with increasing mass velocity and d/D.

  10. Critical Current Measurements in Commercial Tapes, Coils, and Magnets.

    Science.gov (United States)

    Gubser, D. U.; Soulen, R. J., Jr.; Fuller-Mora, W. W.; Francavilla, T. L.

    1996-03-01

    We have measured a number of tapes, coils, and magnets produced by commercial vendors and determined their properties as functions of magnetic field and temperature. The tapes were measured at the National High Magnetic Field Laboratory in magnetic fields to 20 tesla and at temperatures of 4.2 K, 27 K, 65 K, and 77 K. For the tapes we report critical currents and current-voltage characteristics. Six inch diameter coils were measured at NRL in zero magnetic field. Critical currents, current-voltage characteristics, and reliability studies are reported for the coils. Larger 10 inch diameter coils, which are to be used in a 200 hp superconducting motor, were also measured and results will be presented. The talk will also review the status of the most recent tests of the superconducting motor.

  11. Convective heat transfer enhancement inside tubes using inserted helical coils

    Science.gov (United States)

    Ali, R. K.; Sharafeldeen, M. A.; Berbish, N. S.; Moawed, M. A.

    2016-01-01

    Convective heat transfer was experimentally investigated in tubes with helical coils inserts in turbulent flow regime within Reynolds number range of 14400 ≤ Re ≤ 42900. The present work aims to extend the experimental data available on wire coil inserts to cover wire diameter ratio from 0.044 to 0.133 and coil pitch ratio from 1 to 5. Uniform heat flux was applied to the external surface of the tube and air was selected as fluid. The effects of Reynolds number and wire diameter and coil pitch ratios on the Nusselt number and friction factor were studied. The enhancement efficiency and performance criteria ranges are of (46.9-82.6%) and (100.1-128%) within the investigated range of the different parameters, respectively. Correlations are obtained for the average Nusselt number and friction factor utilizing the present measurements within the investigated range of geometrical parameters and Re.

  12. Leveraging voice

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    2017-01-01

    researchers improve our practices and how could digital online video help offer more positive stories about research and higher education? How can academics in higher education be better to tell about our research, thereby reclaiming and leveraging our voice in a post-factual era? As higher education......This paper speculates on how researchers share research without diluting our credibility and how to make strategies for the future. It also calls for consideration of new traditions and practices for communicating knowledge to a wider audience across multiple media platforms. How might we...... continues to engage with digital and networked technologies it becomes increasingly relevant to question why and how academics could (re) position research knowledge in the digital and online media landscape of today and the future. The paper highlights methodological issues that arise in relation...

  13. Endovascular Biopsy: Evaluating the Feasibility of Harvesting Endothelial Cells Using Detachable Coils

    Science.gov (United States)

    Cooke, Daniel L.; Su, Hua; Sun, Zhengda; Guo, Yi; Guo, Diana; Saeed, Maythem M.; Hetts, Steven W.; Higashida, Randall T.; Dowd, Christopher F.; Young, William L.; Halbach, Van V.

    2013-01-01

    Summary The absence of safe and reliable methods to harvest vascular tissue in situ limits the discovery of the underlying genetic and pathophysiological mechanisms of many vascular disorders such as aneurysms. We investigated the feasibility and comparable efficacy of endothelial cell collection using a spectrum of endovascular coils. Nine detachable coils ranging in k coefficient (0.15-0.24), diameter (4.0 mm-16.0 mm), and length (8.0 cm-47.0 cm) were tested in pigs. All coils were deployed and retrieved within the iliac artery of pigs (three coils/pig). Collected coils were evaluated under light microscopy. The total and endothelial cells collected by each coil were quantified. The nucleated cells were identified by Wright-Giemsa and DAPI stains. Endothelial and smooth muscle cells were identified by CD31 and α-smooth muscle actin antibody staining. Coils were deployed and retrieved without technical difficulty. Light microscopy demonstrated sheets of cellular material concentrated within the coil winds. All coils collected cellular material while five of nine (55.6%) coils retrieved endothelial cells. Coils collected mean endothelial cell counts of 89.0±101.6. Regression analysis demonstrated a positive correlation between increasing coil diameter and endothelial cell counts (R2=0.52, p = 0.029). Conventional detachable coils can be used to harvest endothelial cells. The number of endothelial cells collected by a coil positively correlated with its diameter. Given the widespread use of coils and their well-described safety profile their potential as an endovascular biopsy device would expand the availability of tissue for cellular and molecular analysis. PMID:24355142

  14. Evaluation of the heat transfer performance of helical coils of non-circular tubes

    Institute of Scientific and Technical Information of China (English)

    Jundika C.KURNIA; Agus P.SASMITO; Arun S.MUJUMDAR

    2011-01-01

    This study addresses heat transfer performance of various configurations of coiled non-circular tubes, e. g. , in-plane spiral ducts, helical spiral ducts, and conical spiral ducts. The laminar flow of a Newtonian fluid in helical coils made of square cross section tubes is simulated using the computational fluid dynamic approach. The effects of tube Reynolds number, fluid Prandtl number, coil diameter, etc. , are quantified and discussed. Both constant wall temperature and constant heat flux conditions are simulated. The effect of in-plane coil versus a cylindrical design of constant coil, as well as a conical coil design is discussed. Results are compared with those for a straight square tube of the same length as that used to form the coils. Advantages and limitations of using coiled tubes are discussed in light of the numerical results.

  15. Coiled coils and SAH domains in cytoskeletal molecular motors.

    Science.gov (United States)

    Peckham, Michelle

    2011-10-01

    Cytoskeletal motors include myosins, kinesins and dyneins. Myosins move along tracks of actin filaments, whereas kinesins and dyneins move along microtubules. Many of these motors are involved in trafficking cargo in cells. However, myosins are mostly monomeric, whereas kinesins are mostly dimeric, owing to the presence of a coiled coil. Some myosins (myosins 6, 7 and 10) contain an SAH (single α-helical) domain, which was originally thought to be a coiled coil. These myosins are now known to be monomers, not dimers. The differences between SAH domains and coiled coils are described and the potential roles of SAH domains in molecular motors are discussed.

  16. An Air Bearing Rotating Coil Magnetic Measurement System

    CERN Document Server

    Gottschalk, Stephen C; Taylor, David J; Thayer, William

    2005-01-01

    This paper describes a rotating coil magnetic measurement system supported on air bearings. The design is optimized for measurements of 0.1micron magnetic centerline changes on long, small aperture quadrupoles. Graphite impregnated epoxy resin is used for the coil holder and coil winding forms. Coil holder diameter is 11 mm with a length between supports of 750mm. A pair of coils is used to permit quadrupole bucking during centerline measurements. Coil length is 616mm, inner radius 1.82mm, outer radius 4.74mm. The key features of the mechanical system are simplicity; air bearings for accurate, repeatable measurements without needing warm up time and a vibration isolated stand that uses a steel-topped Newport optical table with air suspension. Coil rotation is achieved by a low noise servo motor controlled by a standalone Ethernet servo board running custom servo software. Coil calibration procedures that correct wire placement errors, tests for mechanical resonances, and other system checks will also be discu...

  17. Design and Construction of a Prototype Solenoid Coil for MICE Coupling Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Li; Pan, Heng; Guo, XingLong; Xu, FengYu; Liu, XiaoKun; Wu, Hong; Zheng, ShiXian; Green, Michael A; Li, Derun; Virostek, Steve; Zisman, Michael

    2010-06-28

    A superconducting coupling solenoid mounted around four conventional RF cavities, which produces up to 2.6 T central magnetic field to keep the muons within the cavities, is to be used for the Muon Ionization Cooling Experiment (MICE). The coupling coil made from copper matrix NbTi conductors is the largest of three types of magnets in MICE both in terms of 1.5 m inner diameter and about 13MJ stored magnetic energy at full operation current of 210A. The stress induced inside the coil assembly during cool down and magnet charging is relatively high. In order to validate the design method and develop the coil winding technique with inside-wound SC splices required for the coupling coil, a prototype coil made from the same conductor and with the same diameter and thickness but only one-fourth long as the coupling coil was designed and fabricated by ICST. The prototype coil was designed to be charged to strain conditions that are equivalent or greater than would be encountered in the coupling coil. This paper presents detailed design of the prototype coil as well as developed coil winding skills. The analyses on stress in the coil assembly and quench process were carried out.

  18. TESLA Coil Research

    Science.gov (United States)

    1992-05-01

    Sloan’s work was actually predated by the earlier work of Nikola Tesla . Sloan mistakenly identified " Tesla Coils" as lumped tuned resonators. The...Lefvw WsnJ L REPORT o]i 3. REPRT TYPE AND OATES COVEIRD May 1992 Special/Aug 1992 - May 1992 Z TITLE AND 5U§nUT S. FUNDING NUMIHRS Tesla Coil Research...STATEMENT 1211. ’ISTRIUUTION COOD Approved for public release; dis~ribution is unlimited 13. ABSTRACT (Masrmum 200 worw) High repetition rate Tesla

  19. Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe

    Directory of Open Access Journals (Sweden)

    Okuzaki Daisuke

    2007-05-01

    Full Text Available Abstract Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are required for their function as a putative recombinase cofactor complex during meiotic recombination. Mcp6/Hrs1 and Mcp5/Num1 control horsetail chromosome movement by astral microtubule organization and anchoring dynein respectively. Dhc1 and Ssm4 are also required for horsetail chromosome movement. It is clear from these examples that the coiled-coil motif in these proteins plays an important role during the progression of cells through meiosis. However, there are still many unanswered questions on how these proteins operate. In this paper, we briefly review recent studies on the meiotic coiled-coil proteins in Sz. pombe.

  20. Dimensionality in voice quality.

    Science.gov (United States)

    Bele, Irene Velsvik

    2007-05-01

    This study concerns speaking voice quality in a group of male teachers (n = 35) and male actors (n = 36), as the purpose was to investigate normal and supranormal voices. The goal was the development of a method of valid perceptual evaluation for normal to supranormal and resonant voices. The voices (text reading at two loudness levels) had been evaluated by 10 listeners, for 15 vocal characteristics using VA scales. In this investigation, the results of an exploratory factor analysis of the vocal characteristics used in this method are presented, reflecting four dimensions of major importance for normal and supranormal voices. Special emphasis is placed on the effects on voice quality of a change in the loudness variable, as two loudness levels are studied. Furthermore, the vocal characteristics Sonority and Ringing voice quality are paid special attention, as the essence of the term "resonant voice" was a basic issue throughout a doctoral dissertation where this study was included.

  1. Voice box (image)

    Science.gov (United States)

    The larynx, or voice box, is located in the neck and performs several important functions in the body. The larynx is involved in swallowing, breathing, and voice production. Sound is produced when the air which ...

  2. Voice and Aging

    Science.gov (United States)

    ... dramatic voice changes are those during childhood and adolescence. The larynx (or voice box) and vocal cord tissues do not fully mature until late teenage years. Hormone-related changes during adolescence are ...

  3. Constrained length minimum inductance gradient coil design.

    Science.gov (United States)

    Chronik, B A; Rutt, B K

    1998-02-01

    A gradient coil design algorithm capable of controlling the position of the homogeneous region of interest (ROI) with respect to the current-carrying wires is required for many advanced imaging and spectroscopy applications. A modified minimum inductance target field method that allows the placement of a set of constraints on the final current density is presented. This constrained current minimum inductance method is derived in the context of previous target field methods. Complete details are shown and all equations required for implementation of the algorithm are given. The method has been implemented on computer and applied to the design of both a 1:1 aspect ratio (length:diameter) central ROI and a 2:1 aspect ratio edge ROI gradient coil. The 1:1 design demonstrates that a general analytic method can be used to easily obtain very short gradient coil designs for use with specialized magnet systems. The edge gradient design demonstrates that designs that allow imaging of the neck region with a head sized gradient coil can be obtained, as well as other applications requiring edge-of-cylinder regions of uniformity.

  4. Voice and endocrinology

    OpenAIRE

    KVS Hari Kumar; Anurag Garg; Ajai Chandra, N. S.; Singh, S. P.; Rakesh Datta

    2016-01-01

    Voice is one of the advanced features of natural evolution that differentiates human beings from other primates. The human voice is capable of conveying the thoughts into spoken words along with a subtle emotion to the tone. This extraordinary character of the voice in expressing multiple emotions is the gift of God to the human beings and helps in effective interpersonal communication. Voice generation involves close interaction between cerebral signals and the peripheral apparatus consistin...

  5. DLMS Voice Data Entry.

    Science.gov (United States)

    1980-06-01

    between operator and computer displayed on ADM-3A 20c A-I Possible Hardware Configuration for a Multistation Cartographic VDES ...this program a Voice Recognition System (VRS) which can be used to explore the use of voice data entry ( VDE ) in the DIMS or other cartographic data...Multi-Station Cartographic Voice Data Entry System An engineering development model voice data entry system ( VDES ) could be most efficiently

  6. Eddy sensors for small diameter stainless steel tubes.

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, Jack L.; Morales, Alfredo Martin; Grant, J. Brian; Korellis, Henry James; LaFord, Marianne Elizabeth; Van Blarigan, Benjamin; Andersen, Lisa E.

    2011-08-01

    The goal of this project was to develop non-destructive, minimally disruptive eddy sensors to inspect small diameter stainless steel metal tubes. Modifications to Sandia's Emphasis/EIGER code allowed for the modeling of eddy current bobbin sensors near or around 1/8-inch outer diameter stainless steel tubing. Modeling results indicated that an eddy sensor based on a single axial coil could effectively detect changes in the inner diameter of a stainless steel tubing. Based on the modeling results, sensor coils capable of detecting small changes in the inner diameter of a stainless steel tube were designed, built and tested. The observed sensor response agreed with the results of the modeling and with eddy sensor theory. A separate limited distribution SAND report is being issued demonstrating the application of this sensor.

  7. Ferrite-Cored Solenoidal Induction Coil Sensor for BUD (MM-1667)

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, F.; Becker, A.; Conti, U.; Gasperikova, E.

    2011-06-15

    We have designed and lab tested a new ferrite cored induction coil sensor for measuring the secondary fields from metallic UXO with the BUD system. The objective was to replace the 5-inch diameter air-cored coils in the BUD system with smaller sensors that would allow the placement of multiple sensors in the smaller package of the new BUD hand-held system. A ferrite-cored solenoidal coil of length L can easily be made to have sensitivity and noise level roughly the same as an air-cored coil of a diameter on the same order as L. A ferrite-cored solenoidal coil can easily have a feedback configuration to achieve critical damping. The feedback configuration leads to a very stable response. Feedback ferrite-cored solenoidal coils show very little interaction as long as they are separated by one half their length.

  8. Experimental study of thrusts of a cylindrical linear synchronous motor with an HTS coil magnet as the excitation system

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Wanqing, E-mail: duanwanqing@126.com; Yan, Zhongming, E-mail: 6885391@qq.com; Luo, Wenbo; Zhang, Peixing; Gui, Zhixing; Wang, Zhiquan; Wang, Yu

    2015-01-15

    Highlights: • Thrusts of a cylindrical linear synchronous motor with an HTS coil were measured. • Effects of armature current, coil current and running time were studied. • Thrusts of HTS coil with magnetizers were studied. • Effect of seams between magnetizers was studied. - Abstract: The thrusts of a cylindrical linear synchronous motor with an HTS coil magnet as the excitation system were measured the first time and will be presented in this paper. The HTS coil magnet is made of second generation YBCO wire. The coil is a double pancake coil consisting of 34 turns wire. The inner diameter, outer diameter and height of the coil are 20, 30 and 13 mm, respectively. The armature of the motor is three phases, and the inner diameter is 40 mm. It is made of copper windings. With a direct current of 40 A for the HTS coil magnet and a RMS current of 10 A for the armature, a peak thrust of 3.8 N was measured at the temperature of 77 K and a radial gap of 5 mm between the armature and the excitation system. Effects of armature current, coil current, running time, magnetizers and seams between magnetizers were also studied. In the experiments, the peak thrusts of different types of HTS coil magnets were about from 1.3 times to 8 times as strong as the peak thrust of the coreless coil magnet under the same conditions.

  9. Writing with Voice

    Science.gov (United States)

    Kesler, Ted

    2012-01-01

    In this Teaching Tips article, the author argues for a dialogic conception of voice, based in the work of Mikhail Bakhtin. He demonstrates a dialogic view of voice in action, using two writing examples about the same topic from his daughter, a fifth-grade student. He then provides five practical tips for teaching a dialogic conception of voice in…

  10. Tips for Healthy Voices

    Science.gov (United States)

    ... social interaction as well as for most people’s occupation. Proper care and use of your voice will give you the best chance for having a healthy voice for your entire lifetime. Hoarseness or roughness in your voice is often ...

  11. Planar, monolithically integrated coil

    NARCIS (Netherlands)

    Roozeboom, F.; Reefman, D.; Klootwijk, J.H.; Tiemeijer, L.F.; Ruigrok, J.

    2013-01-01

    The present invention provides a means to integrate planar coils on silicon, while providing a high inductance. This high inductance is achieved through a special back- and front sided shielding of a material. In many applications, high-value inductors are a necessity. In particular, this holds for

  12. An orientable search coil

    Science.gov (United States)

    Holt, P. J.; Poblocki, M.

    2017-01-01

    We provide a design for a low cost orientable search coil that can be used to investigate the variation of magnetic flux with angle. This experiment is one of the required practical activities in the current A level physics specification for the AQA examination board in the UK. We demonstrate its performance and suggest other suitable investigations that can be undertaken.

  13. Interpreting stem diameter changes

    Science.gov (United States)

    Hölttä, T.; Sevanto, S.; Nikinmaa, E.

    2009-12-01

    Detecting phloem transport in stem diameter changes Teemu Hölttä1, Sanna Sevanto2, Eero Nikinmaa1 1Department of Forest Ecology, P.O. Box 27, FIN-00014 University of Helsinki, Finland 2Department of Physics, P.O. Box 48, FIN-00014 University of Helsinki, Finland Introduction The volume of living cells and xylem conduits vary according to pressures they are subjected to. Our proposition is that the behavior of the inner bark diameter variation which cannot be explained by changes in xylem water status arise from changes in the osmotic concentration of the phloem and cambial growth. Materials and methods Simultaneous xylem and stem diameter measurements were conducted between June 28th to October 4th 2006 in Southern Finland on a 47-year old, 15 meter tall, Scots pine tree (DBH 15 cm) at heights of 1.5 and 10 meters. The difference between the measured inner bark diameter and the inner bark diameter predicted from xylem diameter change with a simple model (assuming there was no change in the osmotic concentration of the phloem) is hypothesized to give the changes in the osmotic concentration of the inner bark. The simple model calculates the radial water exchange between the xylem and phloem driven by the water potential changes in the xylem. Results and Discussion The major signal in the inner bark diameter was the transpiration rate as assumed, but also a signal arising from the change in the osmotic concentration (Fig 1a). The predicted osmotic concentration of the phloem typically increased during the afternoon due to the loading of photosynthesized sugars to the phloem. Inner bark osmotic concentration followed the photosynthesis rate with a 3 and 4 hour time-lag at the top and base, respectively (Fig 1b). The connection between photosynthesis and the predicted change in phloem osmotic concentration was stronger in the upper part of the tree compared to lower part. The changes in the predicted osmotic concentration were not similar every day, indicating that

  14. Voice handicap in singers.

    Science.gov (United States)

    Murry, Thomas; Zschommler, Anne; Prokop, Jan

    2009-05-01

    The study aimed to determine the differences in responses to the Voice Handicap Index (VHI-10) between singers and nonsingers and to evaluate the ranked order differences of the VHI-10 statements for both groups. The VHI-10 was modified to include statements related to the singing voice for comparison to the original VHI-10. Thirty-five nonsingers with documented voice disorders responded to the VHI-10. A second group, consisting of 35 singers with voice complaints, responded to the VHI-10 with three statements added specifically addressing the singing voice. Data from both groups were analyzed in terms of overall subject self-rating of voice handicap and the rank order of statements from least to most important. The difference between the mean VHI-10 for the singers and nonsingers was not statistically significant, thus, supporting the validity of the VHI-10. However, the 10 statements were ranked differently in terms of their importance by both groups. In addition, when three statements related specifically to the singing voice were substituted in the original VHI-10, the singers judged their voice problem to be more severe than when using the original VHI-10. The type of statements used to assess self-perception of voice handicap may be related to the subject population. Singers with voice problems do not rate their voices to be more handicapped than nonsingers unless statements related specifically to singing are included.

  15. Experiment of low resistance joints for the ITER correction coil.

    Science.gov (United States)

    Liu, Huajun; Wu, Yu; Wu, Weiyue; Liu, Bo; Shi, Yi; Guo, Shuai

    2013-01-01

    A test method was designed and performed to measure joint resistance of the ITER correction coil (CC) in liquid helium (LHe) temperature. A 10 kA superconducting transformer was manufactured to provide the joints current. The transformer consisted of two concentric layer-wound superconducting solenoids. NbTi superconducting wire was wound in the primary coil and the ITER CC conductor was wound in the secondary coil. The primary and the secondary coils were both immersed in liquid helium of a 300 mm useful bore diameter cryostat. Two ITER CC joints were assembled in the secondary loop and tested. The current of the secondary loop was ramped to 9 kA in several steps. The two joint resistances were measured to be 1.2 nΩ and 1.65 nΩ, respectively.

  16. Minimax Current Density Coil Design

    CERN Document Server

    Poole, Michael; Lopez, Hector Sanchez; Ng, Michael; Crozier, Stuart; 10.1088/0022-3727/43/9/095001

    2010-01-01

    'Coil design' is an inverse problem in which arrangements of wire are designed to generate a prescribed magnetic field when energized with electric current. The design of gradient and shim coils for magnetic resonance imaging (MRI) are important examples of coil design. The magnetic fields that these coils generate are usually required to be both strong and accurate. Other electromagnetic properties of the coils, such as inductance, may be considered in the design process, which becomes an optimization problem. The maximum current density is additionally optimized in this work and the resultant coils are investigated for performance and practicality. Coils with minimax current density were found to exhibit maximally spread wires and may help disperse localized regions of Joule heating. They also produce the highest possible magnetic field strength per unit current for any given surface and wire size. Three different flavours of boundary element method that employ different basis functions (triangular elements...

  17. Singing voice outcomes following singing voice therapy.

    Science.gov (United States)

    Dastolfo-Hromack, Christina; Thomas, Tracey L; Rosen, Clark A; Gartner-Schmidt, Jackie

    2016-11-01

    The objectives of this study were to describe singing voice therapy (SVT), describe referred patient characteristics, and document the outcomes of SVT. Retrospective. Records of patients receiving SVT between June 2008 and June 2013 were reviewed (n = 51). All diagnoses were included. Demographic information, number of SVT sessions, and symptom severity were retrieved from the medical record. Symptom severity was measured via the 10-item Singing Voice Handicap Index (SVHI-10). Treatment outcome was analyzed by diagnosis, history of previous training, and SVHI-10. SVHI-10 scores decreased following SVT (mean change = 11, 40% decrease) (P singing lessons (n = 10) also completed an average of three SVT sessions. Primary muscle tension dysphonia (MTD1) and benign vocal fold lesion (lesion) were the most common diagnoses. Most patients (60%) had previous vocal training. SVHI-10 decrease was not significantly different between MTD and lesion. This is the first outcome-based study of SVT in a disordered population. Diagnosis of MTD or lesion did not influence treatment outcomes. Duration of SVT was short (approximately three sessions). Voice care providers are encouraged to partner with a singing voice therapist to provide optimal care for the singing voice. This study supports the use of SVT as a tool for the treatment of singing voice disorders. 4 Laryngoscope, 126:2546-2551, 2016. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

  18. Clinical Voices - an update

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Weed, Ethan

    Anomalous aspects of speech and voice, including pitch, fluency, and voice quality, are reported to characterise many mental disorders. However, it has proven difficult to quantify and explain this oddness of speech by employing traditional statistical methods. In this talk we will show how the t...... the temporal dynamics of the voice in Asperger's patients enable us to automatically reconstruct the diagnosis, and assess the Autism quotient score. We then generalise the findings to Danish and American children with autism....

  19. Dynamic contrast-enhanced susceptibility-weighted perfusion MRI (DSC-MRI) in a glioma model of the rat brain using a conventional receive-only surface coil with a inner diameter of 47 mm at a clinical 1.5 T scanner.

    Science.gov (United States)

    Ulmer, Stephan; Reeh, Matthias; Krause, Joerg; Herdegen, Thomas; Heldt-Feindt, Janka; Jansen, Olav; Rohr, Axel

    2008-07-30

    Magnetic resonance (MR) imaging in animal models is usually performed in expensive dedicated small bore animal scanners of limited availability. In the present study a standard clinical 1.5 T MR scanner was used for morphometric and dynamic contrast-enhanced susceptibility-weighted MR imaging (DSC-MRI) of a glioma model of the rat brain. Ten male Wistar rats were examined with coronal T2-weighted, and T1-weighted images (matrix 128 x 128, FOV 64 mm) after implantation of an intracerebral tumor xenografts (C6) using a conventional surface coil. For DSC-MRI a T2*-weighted sequence (TR/TE=30/14 ms, matrix 64 x 64, FOV 90 mm; slice thickness of 1.5mm) was performed. Regions of interest were defined within the tumor and the non-affected contralateral hemisphere and the mean transit time (MTT) was determined. Tumor dimensions in MR predicted well its real size as proven by histology. The MTT of contrast agent passing through the brain was significantly decelerated in the tumor compared to the unaffected hemisphere (pscanners or dedicated custom-made coils.

  20. Effects of Medications on Voice

    Science.gov (United States)

    ... ENT Doctor Near You Effects of Medications on Voice Effects of Medications on Voice Patient Health Information ... entnet.org . Could Your Medication Be Affecting Your Voice? Some medications including prescription, over-the-counter, and ...

  1. Performance of multi tubes in tube helically coiled as a compact heat exchanger

    Science.gov (United States)

    Nada, S. A.; El Shaer, W. G.; Huzayyin, A. S.

    2014-12-01

    Multi tubes in tube helically coiled heat exchanger is proposed as a compact heat exchanger. Effects of heat exchanger geometric parameters and fluid flow parameters; namely number of inner tubes, annulus hydraulic diameter, Reynolds numbers and input heat flux, on performance of the heat exchanger are experimentally investigated. Different coils with different numbers of inner tubes, namely 1, 3, 4 and 5 tubes, were tested. Results showed that coils with 3 inner tubes have higher values of heat transfer coefficient and compactness parameter (bar{h} Ah ). Pressure drop increases with increasing both of Reynolds number and number of inner tubes. Correlations of average Nusselt number were deduced from experimental data in terms of Reynolds number, Prandtl number, Number of inner coils tubes and coil hydraulic diameter. Correlations prediction was compared with experimental data and the comparison was fair enough.

  2. Electrohydrodynamic direct-writing of three-dimensional multi-loop nanofibrous coils

    Science.gov (United States)

    Zheng, Gaofeng; Yu, Zhaojie; Zhuang, Mingfeng; Wei, Wen; Zhao, Yang; Zheng, Jiangyi; Sun, Daoheng

    2014-07-01

    This paper studies the whipping deposition behavior of straight charged jets of Near-Field Electrospinning. A micro 3D structure of multi-loop nanofibrous coil was printed on a silicon collector. The whipping motion resulted from Coulomb force caused the charged jet to deposit and form a coiled structure. With the guidance of deposited nanofiber, the charged jet deposited layer by layer to build up a 3D nanofibrous coiled structure with 3-50 loops. The diameter of the coiled structure ranged from 4 to 60 μm. The number of loops decreased with the increase of collector motion speed, due to shorter post-deposition relaxing time. With higher stress inside the charged jet, PEO solution of higher concentration led to fewer loops but larger diameter of the coil. This work provides a promising method to study the control technology of charged jet printing, which may push forward the development of micro 3D inkjet printing technology.

  3. Experimental investigation on heat transfer analysis of conical coil heat exchanger with 90° cone angle

    Science.gov (United States)

    Purandare, Pramod S.; Lele, Mandar M.; Gupta, Raj Kumar

    2015-03-01

    In the present study, an experimental investigation on thermal performance of the conical coil heat exchanger with 90° conical coil heat exchanger is reported. Three different conical coil heat exchangers of same mean coil diameter (Dm = 200 mm) with different tube diameters ( di = 8, 10, 12.5 mm) are analyzed under steady state condition. The analysis is carried out for the tube side hot fluid flow range of 10-100 lph ( Re = 500-5,000), while the shell side flow range of 30-90 lph. The data available from experimentation leads to evaluate heat transfer coefficients for inside and outside the tube of the conical coil heat exchanger by Wilsons plot method. The calculations are further extended to estimate Nusselt Number ( Nu) and effectiveness. The empirical correlations are proposed for predicting Nu and the outlet temperatures of hot and cold fluids. The predicted empirical correlations show reasonable agreement with the experimental results within the given range of parameters.

  4. Introduction to COIL

    OpenAIRE

    Kane, David

    2008-01-01

    By reciprocal arrangement between WIT and the National College of Ireland, you are now able to access their collection directly - more than 100,000 items. This form of direct consortial borrowing has never been tried before in Ireland. Before you borrow your first book, you will have to set up a COIL account, which is straightforward. The items which you reserve online will be posted to us, for you to collect, at the front desk in the Luke Wadding library, afterwards. The Initiat...

  5. Magnetic pressure in electromagnetic tube forming with echelon coil

    Institute of Scientific and Technical Information of China (English)

    ZHAO Zhi-heng; YU Hai-ping; LI Chun-feng; LI Zhong

    2008-01-01

    The effects of geometrical characteristics of echelon coil on the magnetic pressure distribution and their contribution to the final shape of parts were focused and investigated through experiments and numerical simulation using FEM software ANSYS.The results show that the geometrical characteristics of echelon coil play a key role in controlling the magnetic pressure acting on the tube.They show a hump·like distribution near the interface between bigger diameter region and transition region of echelon coil,and affect the final shape of tubular parts then.With the reduction of relative diameter,the magnetic pressure in smaller diameter region decreases and its distribution gradient in transition region increases.With the augment of relative length,the magnetic pressure increases in bigger diameter region,while it almost remains constant in smaller diameter region,and the gradient in transition region enhances sharply.The distribution of magnetic pressure in the axial direction of tube agrees well with the profile of specimen.

  6. Design of an MgB2 race track coil for a wind generator pole demonstration

    DEFF Research Database (Denmark)

    Abrahamsen, Asger Bech; Magnusson, Niklas; Jensen, Bogi Bech;

    2014-01-01

    An MgB2 race track coil intended for demonstrating a down scaled pole of a 10 MW direct drive wind turbine generator has been designed. The coil consists of 10 double pancake coils stacked into a race track coil with a cross section of 84 mm × 80 mm. The length of the straight section is 0.5 m...... and the diameter of the end sections is 0.3 m. Expanded to a straight section of 3.1 m it will produce about 1.5 T magnetic flux density in the air gap of the 10 MW 32 pole generator and about 3.0 T at the edge of the superconducting coil with an operation current density of the coil of 70 A/mm2....

  7. Triple Halo Coil: Development and Comparison with Other TMS Coils

    Science.gov (United States)

    Rastogi, Priyam; Hadimani, Ravi; Jiles, David

    Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation technique that can be used for the treatment of various neurological disorders such as Parkinson's Disease, PTSD, TBI and anxiety by regulating synaptic activity. TMS is FDA approved for the treatment of major depressive disorder. There is a critical need to develop deep TMS coils that can stimulate deeper regions of the brain without excessively stimulating the cortex in order to provide an alternative to surgical methods. We have developed a novel multi-coil configuration called ``Triple Halo Coil'' (THC) that can stimulate deep brain regions. Investigation of induced electric and magnetic field in these regions have been achieved by computer modelling. Comparison of the results due to THC configuration have been conducted with other TMS coils such as ``Halo Coil'', circular coil and ``Figure of Eight'' coil. There was an improvement of more than 15 times in the strength of magnetic field, induced by THC configuration at 10 cm below the vertex of the head when compared with the ``Figure of Eight'' coil alone. Carver Charitable Trust.

  8. Voiced Reading and Rhythm

    Institute of Scientific and Technical Information of China (English)

    詹艳萍

    2007-01-01

    Since voiced reading is an important way in learning English,rhythm is the most critical factor that enables to read beautifully.This article illustrates the relationship between rhythm and voiced reading,the importance of rhythm,and the methods to develop the sense of rhythm.

  9. Clinical Voices - an update

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Weed, Ethan

    Anomalous aspects of speech and voice, including pitch, fluency, and voice quality, are reported to characterise many mental disorders. However, it has proven difficult to quantify and explain this oddness of speech by employing traditional statistical methods. In this talk we will show how...

  10. Borderline Space for Voice

    Science.gov (United States)

    Batchelor, Denise

    2012-01-01

    Being on the borderline as a student in higher education is not always negative, to do with marginalisation, exclusion and having a voice that is vulnerable. Paradoxically, being on the edge also has positive connections with integration, inclusion and having a voice that is strong. Alternative understandings of the concept of borderline space can…

  11. Voice and endocrinology

    Directory of Open Access Journals (Sweden)

    KVS Hari Kumar

    2016-01-01

    Full Text Available Voice is one of the advanced features of natural evolution that differentiates human beings from other primates. The human voice is capable of conveying the thoughts into spoken words along with a subtle emotion to the tone. This extraordinary character of the voice in expressing multiple emotions is the gift of God to the human beings and helps in effective interpersonal communication. Voice generation involves close interaction between cerebral signals and the peripheral apparatus consisting of the larynx, vocal cords, and trachea. The human voice is susceptible to the hormonal changes throughout life right from the puberty until senescence. Thyroid, gonadal and growth hormones have tremendous impact on the structure and function of the vocal apparatus. The alteration of voice is observed even in physiological states such as puberty and menstruation. Astute clinical observers make out the changes in the voice and refer the patients for endocrine evaluation. In this review, we shall discuss the hormonal influence on the voice apparatus in normal and endocrine disorders.

  12. Face the voice

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2014-01-01

    will be based on a reception aesthetic and phenomenological approach, the latter as presented by Don Ihde in his book Listening and Voice. Phenomenologies of Sound , and my analytical sketches will be related to theoretical statements concerning the understanding of voice and media (Cavarero, Dolar, La...

  13. Voice integrated systems

    Science.gov (United States)

    Curran, P. Mike

    1977-01-01

    The program at Naval Air Development Center was initiated to determine the desirability of interactive voice systems for use in airborne weapon systems crew stations. A voice recognition and synthesis system (VRAS) was developed and incorporated into a human centrifuge. The speech recognition aspect of VRAS was developed using a voice command system (VCS) developed by Scope Electronics. The speech synthesis capability was supplied by a Votrax, VS-5, speech synthesis unit built by Vocal Interface. The effects of simulated flight on automatic speech recognition were determined by repeated trials in the VRAS-equipped centrifuge. The relationship of vibration, G, O2 mask, mission duration, and cockpit temperature and voice quality was determined. The results showed that: (1) voice quality degrades after 0.5 hours with an O2 mask; (2) voice quality degrades under high vibration; and (3) voice quality degrades under high levels of G. The voice quality studies are summarized. These results were obtained with a baseline of 80 percent recognition accuracy with VCS.

  14. Ontario's Student Voice Initiative

    Science.gov (United States)

    Courtney, Jean

    2014-01-01

    This article describes in some detail aspects of the Student Voice initiative funded and championed by Ontario's Ministry of Education since 2008. The project enables thousands of students to make their voices heard in meaningful ways and to participate in student-led research. Some students from grades 7 to 12 become members of the Student…

  15. Design and Performance of the First Dual-Coil Magnet at the Wuhan National High Magnetic Field Center

    Science.gov (United States)

    Peng, T.; Sun, Q. Q.; Zhang, X.; Xu, Q.; Xiao, H. X.; Herlach, F.; Pan, Y.; Li, L.

    2013-03-01

    The first 80 T dual-coil magnet was manufactured and tested at the Wuhan National High Magnetic Field Center (WHMFC). The inner coil consists of 8 layers of 2.8 mm × 4.3 mm CuNb microcomposite wire developed in China; the bore diameter is 14 mm and the outer diameter 135 mm. The outer coil was wound directly on the inner coil with 12 layers of 3 mm × 6 mm soft copper. Each conductor layer of both coils was reinforced by Zylon/epoxy composite. The inner and outer coil were driven by a 1.6 MJ/5.12 mF capacitor bank and by eight 1 MJ/3.2 mF modules, respectively. At the voltage of 14.3 kV for the inner coil and 22 kV for the outer coil, the inner and outer coils produced peak fields of 48.5 T and 34.5 T respectively, which gave a total field of 83 T. This was the first combined operation of the new capacitor banks installed at the WHMFC. We present details of the design, manufacture and test of the dual-coil magnet and discuss crucial material properties. Based on this experience, a second dual-coil magnet will be designed; the enhanced design will be discussed. With the total energy of 12.6 MJ, peak field up to 90 T is expected.

  16. EasyVoice: Integrating voice synthesis with Skype

    CERN Document Server

    Condado, Paulo A

    2007-01-01

    This paper presents EasyVoice, a system that integrates voice synthesis with Skype. EasyVoice allows a person with voice disabilities to talk with another person located anywhere in the world, removing an important obstacle that affect these people during a phone or VoIP-based conversation.

  17. Voice Savers for Music Teachers

    Science.gov (United States)

    Cookman, Starr

    2012-01-01

    Music teachers are in a class all their own when it comes to voice use. These elite vocal athletes require stamina, strength, and flexibility from their voices day in, day out for hours at a time. Voice rehabilitation clinics and research show that music education ranks high among the professionals most commonly affected by voice problems.…

  18. Neural mechanisms for voice recognition

    NARCIS (Netherlands)

    Andics, A.V.; McQueen, J.M.; Petersson, K.M.; Gal, V.; Rudas, G.; Vidnyanszky, Z.

    2010-01-01

    We investigated neural mechanisms that support voice recognition in a training paradigm with fMRI. The same listeners were trained on different weeks to categorize the mid-regions of voice-morph continua as an individual's voice. Stimuli implicitly defined a voice-acoustics space, and training expli

  19. Structural and biochemical characterizations of an intramolecular tandem coiled coil protein.

    Science.gov (United States)

    Shin, Donghyuk; Kim, Gwanho; Kim, Gyuhee; Zheng, Xu; Kim, Yang-Gyun; Lee, Sangho

    2014-12-12

    Coiled coil has served as an excellent model system for studying protein folding and developing protein-based biomaterials. Most designed coiled coils function as oligomers, namely intermolecular coiled coils. However, less is known about structural and biochemical behavior of intramolecular coiled coils where coiled coil domains are covalently linked in one polypeptide. Here we prepare a protein which harbors three coiled coil domains with two short linkers, termed intramolecular tandem coiled coil (ITCC) and characterize its structural and biochemical behavior in solution. ITCC consists of three coiled coil domains whose sequences are derived from Coil-Ser and its domain swapped dimer. Modifications include positioning E (Glu) residue at "e" and K (Lys) at "g" positions throughout heptad repeats to enhance ionic interaction among its constituent coiled coil domains. Molecular modeling of ITCC suggests a compact triple helical bundle structure with the second and the third coiled coil domains forming a canonical coiled coil. ITCC exists as a mixture of monomeric and dimeric species in solution. Small-angle X-ray scattering reveals ellipsoidal molecular envelopes for both dimeric and monomeric ITCC in solution. The theoretically modeled structures of ITCC dock well into the envelopes of both species. Higher ionic strength shifts the equilibrium into monomer with apparently more compact structure while secondary structure remains unchanged. Taken together, our results suggest that our designed ITCC is predominantly monomeric structure through the enhanced ionic interactions, and its conformation is affected by the concentration of ionic species in the buffer.

  20. Analytical Model and Optimized Design of Power Transmitting Coil for Inductively Coupled Endoscope Robot.

    Science.gov (United States)

    Ke, Quan; Luo, Weijie; Yan, Guozheng; Yang, Kai

    2016-04-01

    A wireless power transfer system based on the weakly inductive coupling makes it possible to provide the endoscope microrobot (EMR) with infinite power. To facilitate the patients' inspection with the EMR system, the diameter of the transmitting coil is enlarged to 69 cm. Due to the large transmitting range, a high quality factor of the Litz-wire transmitting coil is a necessity to ensure the intensity of magnetic field generated efficiently. Thus, this paper builds an analytical model of the transmitting coil, and then, optimizes the parameters of the coil by enlarging the quality factor. The lumped model of the transmitting coil includes three parameters: ac resistance, self-inductance, and stray capacitance. Based on the exact two-dimension solution, the accurate analytical expression of ac resistance is derived. Several transmitting coils of different specifications are utilized to verify this analytical expression, being in good agreements with the measured results except the coils with a large number of strands. Then, the quality factor of transmitting coils can be well predicted with the available analytical expressions of self- inductance and stray capacitance. Owing to the exact estimation of quality factor, the appropriate coil turns of the transmitting coil is set to 18-40 within the restrictions of transmitting circuit and human tissue issues. To supply enough energy for the next generation of the EMR equipped with a Ø9.5×10.1 mm receiving coil, the coil turns of the transmitting coil is optimally set to 28, which can transfer a maximum power of 750 mW with the remarkable delivering efficiency of 3.55%.

  1. An Asymmetric Birdcage Coil for Small-animal MR Imaging at 7T.

    Science.gov (United States)

    Kim, Kyoung-Nam; Han, Sang-Doc; Seo, Jeung-Hoon; Heo, Phil; Yoo, Dongkyeom; Im, Geun Ho; Lee, Jung Hee

    2016-09-30

    The birdcage (BC) coil is currently being utilized for uniform radiofrequency (RF) transmit/receive (Tx/Rx) or Tx-only configuration in many magnetic resonance (MR) imaging applications, but insufficient magnetic flux (|B1|) density and their non-uniform distribution still exists in high-field (HF) environments. We demonstrate that the asymmetric birdcage (ABC) transmit/receive (Tx/Rx) volume coil, which is a modified standard birdcage (SBC) coil with the end ring split into two halves, is suitable for improving the |B1| sensitivity in 7T small-animal MR imaging. Cylindrical SBC and ABC coils with 35 mm diameter were constructed and bench tested for mouse body MR imaging at 300 MHz using a 7T scanner. To assess the ABC coil performance, computational electromagnetic (EM) simulation and 7T MR experiment were performed by using a cylindrical phantom and in vivo mouse body and quantitatively compared with the SBC coil in terms of |B1| distribution, RF transmit (|B1(+)|) field, and signal-to-noise ratio (SNR). The bench measurements of the two BC coils are similar, yielding a quality value (Q-value) of 74.42 for the SBC coil and 77.06 for the ABC coil. The computational calculation results clearly show that the proposed ABC coil offers superior |B1| field and |B1(+)| field sensitivity in the central axial slice compared with the SBC coil. There was also high SNR and uniformly distributed flip angle (FA) under the loaded condition of mouse body in the 7T experiment. Although ABC geometry allows a further increase in the |B1| field and |B1(+)| field sensitivity in only the central axial slice, the geometrical modification of the SBC coil can make a high performance RF coil feasible in the central axial slice and also make target imaging possible in the diagonal direction.

  2. Progress on the Coupling Coil for the MICE Channel

    Energy Technology Data Exchange (ETDEWEB)

    Green, M.A.; Li, D.; Virostek, S.P.; Lau, W.; Witte, H.; Yang,S.Q.; Drumm, P.; Ivanyushenkov, Y.

    2005-05-08

    This report describes the progress on the coupling magnet for the international Muon Ionization Cooling Experiment (MICE). MICE consists of two cells of a SFOFO cooling channel that is similar to that studied in the level 2 study of a neutrino factory. The MICE RF coupling coil module (RFCC module) consists of a 1.56 m diameter superconducting solenoid, mounted around four cells of conventional 201.25 MHz closed RF cavities. This report discusses the progress that has been made on the superconducting coupling coil that is around the center of the RF coupling module. This report describes the process by which one would cool the coupling coil using a single small 4 K cooler. In addition, the coupling magnet power system and quench protection system are also described.

  3. Double diameter boring tool

    Science.gov (United States)

    Ashbaugh, Fred N.; Murry, Kenneth R.

    1988-12-27

    A boring tool and a method of operation are provided for boring two concentric holes of precision diameters and depths in a single operation. The boring tool includes an elongated tool body, a shank for attachment to a standard adjustable boring head which is used on a manual or numerical control milling machine and first and second diametrically opposed cutting edges formed for cutting in opposite directions. The diameter of the elongated tool body is substantially equal to the distance from the first cutting edge tip to the axis of rotation plus the distance from the second cutting edge tip to the axis of rotation. The axis of rotation of the tool is spaced from the tool centerline a distance substantially equal to one-half the distance from the second cutting edge tip to the axis of rotation minus one-half the distance from the first cutting edge tip to the axis of rotation. The method includes the step of inserting the boring tool into the boring head, adjusting the distance between the tool centerline and the tool axis of rotation as described above and boring the two concentric holes.

  4. Experimental study on in-tube condensation heat transfer characteristics of helically coiled spiral tubes

    Energy Technology Data Exchange (ETDEWEB)

    Park, J.U. [Sunchon First College, Sunchon (Korea); Kweon, Y.C. [Sun Moon University, Chonan (Korea); Han, K.I. [Pukyong National University, Pusan (Korea)

    2001-12-01

    An experimental study on condensation heat transfer characteristics of helically coiled spiral tubes was performed. The refrigerant is R-113. A refrigerant loop was established to measure the condensation heat transfer coefficients. Experiments were carried out uniform heat flux of 15 kW/m{sup 2}, refrigerant quality of 0.1 {approx} 0.9, curvature ratio of 0.016, 0.025 and 0.045. The curvature of a coil was defined as the ratio of the inside diameter of the tube to the diameter of the bending circle. To compare the condensation heat transfer coefficients of coiled spiral tubes, the previous results on coiled plain tubes and straight plain tubes were used. The results shows that the condensation heat transfer coefficients of coiled spiral tubes largely increase, as increasing Re and quality, compared to those of coiled plain tubes and straight plain tubes. As increasing degree of subcooling, however, the condensation heat transfer coefficients on coiled spiral tubes decrease. It is found that the heat transfer enhancement is more better than coiled plain tubes and straight plain tubes, as increasing curvature ratio. (author). 13 refs., 10 figs., 1 tab.

  5. Dominant Voice in Hamlet

    Institute of Scientific and Technical Information of China (English)

    李丹

    2015-01-01

    <正>The Tragedy of Hamlet dramatizes the revenge Prince Hamlet exacts on his uncle Claudius for murdering King Hamlet,Claudius’s brother and Prince Hamlet’s father,and then succeeding to the throne and taking as his wife Gertrude,the old king’s widow and Prince Hamlet’s mother.This paper will discuss something about dominant voice in the play.Dominant voice is the major voice in the country,the society,or the whole world.Those people who have the power or

  6. CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

    DEFF Research Database (Denmark)

    Bartoli, Lisa; Fariselli, Piero; Krogh, Anders;

    2009-01-01

    MOTIVATION: The widespread coiled-coil structural motif in proteins is known to mediate a variety of biological interactions. Recognizing a coiled-coil containing sequence and locating its coiled-coil domains are key steps towards the determination of the protein structure and function. Different...... tools are available for predicting coiled-coil domains in protein sequences, including those based on position-specific score matrices and machine learning methods. RESULTS: In this article, we introduce a hidden Markov model (CCHMM_PROF) that exploits the information contained in multiple sequence...... alignments (profiles) to predict coiled-coil regions. The new method discriminates coiled-coil sequences with an accuracy of 97% and achieves a true positive rate of 79% with only 1% of false positives. Furthermore, when predicting the location of coiled-coil segments in protein sequences, the method reaches...

  7. Coiled-coil conformation of a pentamidine-DNA complex.

    Science.gov (United States)

    Moreno, Tadeo; Pous, Joan; Subirana, Juan A; Campos, J Lourdes

    2010-03-01

    The coiled-coil structure formed by the complex of the DNA duplex d(ATATATATAT)(2) with pentamidine is presented. The duplex was found to have a mixed structure containing Watson-Crick and Hoogsteen base pairs. The drug stabilizes the coiled coil through the formation of cross-links between neighbouring duplexes. The central part of the drug is found in the minor groove as expected, whereas the charged terminal amidine groups protrude and interact with phosphates from neighbouring molecules. The formation of cross-links may be related to the biological effects of pentamidine, which is used as an antiprotozoal agent in trypanosomiasis, leishmaniasis and pneumonias associated with AIDS. The DNA sequence that was used is highly abundant in most eukaryotic genomes. However, very few data are available on DNA sequences which only contain A.T base pairs.

  8. Background field coils for the High Field Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Zbasnik, J.P.; Cornish, D.N.; Scanlan, R.M.; Jewell, A.M.; Leber, R.L.; Rosdahl, A.R.; Chaplin, M.R.

    1980-09-22

    The High Field Test Facility (HFTF), presently under construction at LLNL, is a set of superconducting coils that will be used to test 1-m-o.d. coils of prototype conductors for fusion magnets in fields up to 12 T. The facility consists of two concentric sets of coils; the outer set is a stack of Nb-Ti solenoids, and the inner set is a pair of solenoids made of cryogenically-stabilized, multifilamentary Nb/sub 3/Sn superconductor, developed for use in mirror-fusion magnets. The HFTF system is designed to be parted along the midplane to allow high-field conductors, under development for Tokamak fusion machines, to be inserted and tested. The background field coils were wound pancake-fashion, with cold-welded joints at both the inner and outer diameters. Turn-to-turn insulation was fabricated at LLNL from epoxy-fiberglass strip. The coils were assembled and tested in our 2-m-diam cryostat to verify their operation.

  9. Ethnographic Voice Memo Narratives

    DEFF Research Database (Denmark)

    Rasmussen, Mette Apollo; Conradsen, Maria Bosse

    1800-01-01

    -based technique which actively involves actors in producing ethnography-based data concerning their everyday practice. With the help from smartphone technology it is possible to complement ethnography-based research methods when involving the actors and having them create small voice memo narratives. The voice...... memos create insights of actors‟ everyday practice, without the direct presence of a researcher and could be considered a step towards meeting the dilemmas of research in complex fieldwork settings....

  10. Can Magnetic Coil Ease Tinnitus?

    Science.gov (United States)

    ... Research Updates Technology Horizons Can magnetic coil ease tinnitus? VA trial aims to find out February 3, ... pain. See, for example, this 2009 review study . Tinnitus and Veterans Tinnitus has been one of the ...

  11. First coil for the SC

    CERN Multimedia

    CERN PhotoLab

    1955-01-01

    The coils for the SC magnet were stored in the large hangar of the Cointrin Airport (to make sure that they would be available before snow and ice would block the roads and canals from Belgium, where they were built).

  12. Adjustable Induction-Heating Coil

    Science.gov (United States)

    Ellis, Rod; Bartolotta, Paul

    1990-01-01

    Improved design for induction-heating work coil facilitates optimization of heating in different metal specimens. Three segments adjusted independently to obtain desired distribution of temperature. Reduces time needed to achieve required temperature profiles.

  13. Nylon screws make inexpensive coil forms

    Science.gov (United States)

    Aucoin, G.; Rosenthal, C.

    1978-01-01

    Standard nylon screws act as coil form copper wire laid down in spiral thread. Completed coil may be bonded to printed-circuit board. However, it is impossible to tune coil by adjusting spacing between windings, technique sometimes used with air-core coils.

  14. Nylon screws make inexpensive coil forms

    Science.gov (United States)

    Aucoin, G.; Rosenthal, C.

    1978-01-01

    Standard nylon screws act as coil form copper wire laid down in spiral thread. Completed coil may be bonded to printed-circuit board. However, it is impossible to tune coil by adjusting spacing between windings, technique sometimes used with air-core coils.

  15. HELMHOLTZ COILS FOR MEASURING MAGNETIC MOMENTS

    Directory of Open Access Journals (Sweden)

    P. N. Dobrodeyev

    2013-01-01

    Full Text Available The optimal configuration of the double Helmholtz coils for measuring of the magnetic dipole moments was defined. It was determined that measuring coils should have round shape and compensative coils – the square one. Analytically confirmed the feasibility of the proposed configuration of these coils as primary transmitters of magnetic dipole moments.

  16. A novel method for coiled tubing installation

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Peter J. [2H Offshore, Houston, TX (United States); Tibbetts, David [Aquactic Engineering and Construction Ltd., Aberdeen (United Kingdom)

    2009-12-19

    Installation of flexible pipe for offshore developments is costly due to the physical cost of the flexible pipe, expensive day rates and the availability of suitable installation vessels. Considering the scarcity of flexible pipe in today's increasingly demanding and busy market, operators are seeking a cost effective solution for installing piping in a range of water depths using vessels which are readily on hand. This paper describes a novel approach to installing reeled coiled tubing, from 1 inch to 5 inch diameter, from the back of a small vessel in water depths from 40 m up to around 1000 m. The uniqueness of the system is the fact that the equipment design is modular and compact. This means that when disassembled, it fits into standard 40 ft shipping containers, and the size allows it to be installed on even relatively small vessels of opportunity, such as anchor handling or installation vessels, from smaller, and cheaper quay side locations. Such an approach is the ideal solution to the problem faced by operators, in that it allows the installation of cheaper, readily available coiled tubing, from cost-effective vessels, which do not need to transit to a pick up the system. (author)

  17. Stability test of conduction-cooled LTS/HTS composite coil

    Science.gov (United States)

    Cui, Ying Min; Wang, Yin Shun; Lv, Gang; Pi, Wei

    2016-06-01

    A small LTS/HTS composite coil made of NbTi/Cu and YBCO, with an inner diameter of 80 mm, an outer diameter of 88mm, a height of 50 mm, and an inductance of 5.5 μH, was designed to test its heat disturbance performance in a GM cryocooler. For comparison, a conventional LTS coil of a similar size made of NbTi/Cu wire was also tested. Transport current was applied from 50 A to 700 A at 8 K and 8.5 K, respectively. The two coils’ heat disturbance, minimum quench energy and quench propagation velocity performance were investigated and simulated. The results indicate that the LTS/HTS composite coil shows better thermal stability and is more fit for operation in conductive cryocooler systems compared to LTS coils.

  18. Experimental and numerical study on unsteady natural convection heat transfer in helically coiled tube heat exchangers

    Science.gov (United States)

    Neshat, E.; Hossainpour, S.; Bahiraee, F.

    2014-06-01

    Both of experimental and numerical investigations were performed to understand unsteady natural convection from outer surface of helical coils. Four helical coils with two different curvature ratios were used. Each coil was mounted in the shell both vertically and horizontally. The cold water was entered the coil and the hot water in the shell was cooling by unsteady natural convection. A CFD code was developed to simulate natural convection heat transfer. Equations of tube and shell are solved simultaneously. Statistical analyses have been done on data points of temperature and natural convection Nusselt number. It was revealed that shell-side fluid temperature and the Nusselt number of the outer surface of coils are functions of in-tube fluid mass flow rate, specific heat of fluids and geometrical parameters including length, inner diameter of the tube and the volume of the shell, and time.

  19. Small diameter carbon nanopipettes

    Science.gov (United States)

    Singhal, Riju; Bhattacharyya, Sayan; Orynbayeva, Zulfiya; Vitol, Elina; Friedman, Gary; Gogotsi, Yury

    2010-01-01

    Nanoscale multifunctional carbon probes facilitate cellular studies due to their small size, which makes it possible to interrogate organelles within living cells in a minimally invasive fashion. However, connecting nanotubes to macroscopic devices and constructing an integrated system for the purpose of fluid and electrical signal transfer is challenging, as is often the case with nanoscale components. We describe a non-catalytic chemical vapor deposition based method for batch fabrication of integrated multifunctional carbon nanopipettes (CNPs) with tip diameters much smaller (10-30 nm) than previously reported (200 nm and above) and approaching those observed for multiwalled carbon nanotubes. This eliminates the need for complicated attachment/assembly of nanotubes into nanofluidic devices. Variable tip geometries and structures were obtained by controlled deposition of carbon inside and outside quartz pipettes. We have shown that the capillary length and gas flow rate have a marked effect on the carbon deposition. This gives us a flexible protocol, useful for growing carbon layers of different thicknesses at selective locations on a glass pipette to yield a large variety of cellular probes in bulk quantities. The CNPs possess an open channel for fluid transfer with the carbon deposited inside at 875 °C behaving like an amorphous semiconductor. Vacuum annealing of the CNP tips at temperatures up to 2000 °C yields graphitic carbon structures with an increase in conductivity of two orders of magnitude. Penetration of the integrated carbon nanoprobes into cells was shown to produce minimal Ca2+ signals, fast recovery of basal Ca2+ levels and no adverse activation of the cellular metabolism during interrogation times as long as 0.5-1 h.

  20. Voice Matching Using Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Abhishek Bal

    2014-03-01

    Full Text Available In this paper, the use of Genetic Algorithm (GA for voice recognition is described. The practical application of Genetic Algorithm (GA to the solution of engineering problem is a rapidly emerging approach in the field of control engineering and signal processing. Genetic algorithms are useful for searching a space in multi-directional way from large spaces and poorly defined space. Voice is a signal of infinite information. Digital processing of voice signal is very important for automatic voice recognition technology. Nowadays, voice processing is very much important in security mechanism due to mimicry characteristic. So studying the voice feature extraction in voice processing is very necessary in military, hospital, telephone system, investigation bureau and etc. In order to extract valuable information from the voice signal, make decisions on the process, and obtain results, the data needs to be manipulated and analyzed. In this paper, if the instant voice is not matched with same person’s reference voices in the database, then Genetic Algorithm (GA is applied between two randomly chosen reference voices. Again the instant voice is compared with the result of Genetic Algorithm (GA which is used, including its three main steps: selection, crossover and mutation. We illustrate our approach with different sample of voices from human in our institution.

  1. High-pass bird-cage coil for nuclear-magnetic resonance

    Science.gov (United States)

    Watkins, Joel C.; Fukushima, Eiichi

    1988-06-01

    Cylindrical bird-cage coils generate uniform magnetic fields transverse to the cylinder axis for use in the large sample nuclear-magnetic resonance (NMR) experiments. We describe the design and construction of an eight-rung high-pass bird-cage coil to operate at 80 MHz in a cylindrical bore of a superconducting magnet. The coil is 12.7 cm in diameter by 30.5 cm long and has a 7-cm-diam region in the center where the field intensity is within 10% of the average.

  2. Heat Transfer Characteristics and Performance of a Spirally Coiled Heat Exchanger under Sensible Cooling Conditions

    Science.gov (United States)

    Wongwises, Somchai; Naphon, Paisarn

    In the present study, new experimental data on the heat transfer characteristics and the performance of a spirally coiled heat exchanger under sensible cooling conditions is presented. The spiral-coil heat exchanger consists of a steel shell and a spirally coiled tube unit. The spiral-coil unit consists of six layers of concentric spirally coiled tubes. Each tube is fabricated by bending a 9.27mm diameter straight copper tube into a spiral-coil of five turns. The innermost and outermost diameters of each spiral-coil are 67.7 and 227.6mm, respectively. Air and water are used as working fluids in shell side and tube side, respectively. A mathematical model based on the conservation of energy is developed to determine the heat transfer characteristics. There is a reasonable agreement between the results obtained from the experiment and those obtained from the model and a good agreement for the high air mass flow rate region. The results obtained from the parametric study are also discussed.

  3. Voice Therapy Practices and Techniques: A Survey of Voice Clinicians.

    Science.gov (United States)

    Mueller, Peter B.; Larson, George W.

    1992-01-01

    Eighty-three voice disorder therapists' ratings of statements regarding voice therapy practices indicated that vocal nodules are the most frequent disorder treated; vocal abuse and hard glottal attack elimination, counseling, and relaxation were preferred treatment approaches; and voice therapy is more effective with adults than with children.…

  4. Voice in early glottic cancer compared to benign voice pathology

    NARCIS (Netherlands)

    Van Gogh, C. D. L.; Mahieu, H. F.; Kuik, D. J.; Rinkel, R. N. P. M.; Langendijk, J. A.; Verdonck-de Leeuw, I. M.

    2007-01-01

    The purpose of this study is to compare (Dutch) Voice Handicap Index (VHIvumc) scores from a selected group of patients with voice problems after treatment for early glottic cancer with patients with benign voice disorders and subjects from the normal population. The study included a group of 35 pat

  5. The inner voice

    Directory of Open Access Journals (Sweden)

    Anthony James Ridgway

    2009-12-01

    Full Text Available The inner voice- we all know what it is because we all have it and use it when we are thinking or reading, for example. Little work has been done on it in our field, with the notable exception of Brian Tomlinson, but presumably it must be a cognitive phenomenon which is of great importance in thinking, language learning, and reading in a foreign language. The inner voice will be discussed as a cognitive psychological phenomenon associated with short-term memory, and distinguished from the inner ear. The process of speech recoding will be examined (the process of converting written language into the inner voice and the importance of developing the inner voice, as a means of both facilitating the production of a new language and enhancing the comprehension of a text in a foreign language, will be emphasized. Finally, ways of developing the inner voice in beginning and intermediate readers of a foreign language will be explored and recommended.

  6. Heat transfer characteristics of a new helically coiled crimped spiral finned tube heat exchanger

    Science.gov (United States)

    Srisawad, Kwanchanok; Wongwises, Somchai

    2009-02-01

    In the present study, the heat transfer characteristics in dry surface conditions of a new type of heat exchanger, namely a helically coiled finned tube heat exchanger, is experimentally investigated. The test section, which is a helically coiled fined tube heat exchanger, consists of a shell and a helical coil unit. The helical coil unit consists of four concentric helically coiled tubes of different diameters. Each tube is constructed by bending straight copper tube into a helical coil. Aluminium crimped spiral fins with thickness of 0.5 mm and outer diameter of 28.25 mm are placed around the tube. The edge of fin at the inner diameter is corrugated. Ambient air is used as a working fluid in the shell side while hot water is used for the tube-side. The test runs are done at air mass flow rates ranging between 0.04 and 0.13 kg/s. The water mass flow rates are between 0.2 and 0.4 kg/s. The water temperatures are between 40 and 50°C. The effects of the inlet conditions of both working fluids flowing through the heat exchanger on the heat transfer coefficients are discussed. The air-side heat transfer coefficient presented in term of the Colburn J factor is proportional to inlet-water temperature and water mass flow rate. The heat exchanger effectiveness tends to increase with increasing water mass flow rate and also slightly increases with increasing inlet water temperature.

  7. Temperature Profile Measurements During Heat Treatment of BSCCO 2212 Coils

    Energy Technology Data Exchange (ETDEWEB)

    Tollestrup, Alvin; /Fermilab

    2011-04-14

    The temperature profile of two different BSCCO 2212 coils has been analyzed. The profiles are obtained from thermocouples imbedded in the windings during the heat treatment that activates the 2212. The melting and freezing of the 2212 is clearly observed. A model that describes the data and can be used to guide the processing of new coils has been developed. We have obtained the thermal history of two BSCCO coils, one from NHMFL (1) that had 10 layers of 1 mm diameter wire with 0.15 mm insulation and a second coil from OST that had 24 layers with similar insulation and conductor size. Both coils had thermocouples imbedded in the windings and excellent recordings of the temperature over the whole reaction cycle were available for analysis. There are several features that we will address in this note. Measurements have shown that the I{sub c} of the conductor is a sensitive function of its thermal history. This brings up the question of the absolute accuracy of the thermometry in the range around 882 C, the MP of 2212. The reference for the treatment profile is really related to this MP and to small deviations around it. Since the heat of fusion of 2212 is rather large, it generates a clear signal during the melting and cooling transition that automatically generates the relative temperature markers. The physics is the same as the way ice in water maintains an isothermal environment until it is all melted. A related question is the thermal response time of the coil package. The temperature cycles that are being used to optimize strand and small coils can have rapid changes easily implemented whereas a large coil may have such a large thermal time constant that the optimum cycle may not be attainable. A simple analytical model that works well for small solenoids has been developed and an ANSYS (5) program that works for larger coils with more complicated geometry has been set up but will not be discussed in this note.

  8. Evaluation of the characteristics of various types of coils for the embolization of intracranial aneurysms with an optical pressure sensor system.

    Science.gov (United States)

    Matsubara, Noriaki; Miyachi, Shigeru; Nagano, Yoshitaka; Ohshima, Tomotaka; Hososhima, Osamu; Izumi, Takashi; Tsurumi, Arihito; Wakabayashi, Toshihiko; Sano, Akihito; Fujimoto, Hideo

    2011-03-01

    In coil embolization for an intracranial aneurysm, it is important to appropriately choose the coil most suitable for coping with various unforeseen situations. Additionally, because dense coil packing of the aneurysm sac is the most important factor to avoid a recurrence, properly selecting the coil is essential. In this article, the authors measured the coil insertion pressure of various types of coils with a newly developed sensor system, and coil characteristics were investigated. The sensor consists of a hemostatic valve connected to the proximal end of a microcatheter. The sensor principle is based on an optical system. Using this, an experimental silicone aneurysm embolization was performed automatically at constant speed. The pattern of the insertion pressure and the maximum insertion pressure (MIP) were analyzed for the various types of coils. The sensor continuously monitored the mechanical force during the insertions. The sensor adequately recorded the coil insertion pressure during embolization in each coil. MIP was generally ranked in order of the coil type. The soft type coils required relatively less insertion pressure than standard/helical and 3D type. As for the patterns of coil insertion pressure, each coil presented a saw-like pressure pattern, though we observed some slight differences. 3D type coils showed peak pressure at the moment of "painting". Coil loop diameters barely affected MIP. However, as to the patterns of pressure, larger size coils more often presented the peak. Coil characteristics were well evaluated. The results obtained here reflected some actual clinical experience. Furthermore, collecting the in vivo study is mandatory, which may provide clinically useful data.

  9. Smartphone App for Voice Disorders

    Science.gov (United States)

    ... on. Feature: Taste, Smell, Hearing, Language, Voice, Balance Smartphone App for Voice Disorders Past Issues / Fall 2013 ... developed a mobile monitoring device that relies on smartphone technology to gather a week's worth of talking, ...

  10. Computational analysis of residue contributions to coiled-coil topology.

    Science.gov (United States)

    Ramos, Jorge; Lazaridis, Themis

    2011-11-01

    A variety of features are thought to contribute to the oligomeric and topological specificity of coiled coils. In previous work, we examined the determinants of oligomeric state. Here, we examine the energetic basis for the tendency of six coiled-coil peptides to align their α-helices in antiparallel orientation using molecular dynamics simulations with implicit solvation (EEF1.1). We also examine the effect of mutations known to disrupt the topology of these peptides. In agreement with experiment, ARG or LYS at a or d positions were found to stabilize the antiparallel configuration. The modeling suggests that this is not due to a-a' or d-d' repulsions but due to interactions with e' and g' residues. TRP at core positions also favors the antiparallel configuration. Residues that disfavor parallel dimers, such as ILE at d, are better tolerated in, and thus favor the antiparallel configuration. Salt bridge networks were found to be more stabilizing in the antiparallel configuration for geometric reasons: antiparallel helices point amino acid side chains in opposite directions. However, the structure with the largest number of salt bridges was not always the most stable, due to desolvation and configurational entropy contributions. In tetramers, the extent of stabilization of the antiparallel topology by core residues is influenced by the e' residue on a neighboring helix. Residues at b and c positions in some cases also contribute to stabilization of antiparallel tetramers. This work provides useful rules toward the goal of designing coiled coils with a well-defined and predictable three-dimensional structure.

  11. Experimental investigation on heat transfer and pressure drop of conical coil heat exchanger

    Directory of Open Access Journals (Sweden)

    Purandare Pramod S.

    2016-01-01

    Full Text Available The heat transfer and pressure drop analysis of conical coil heat exchanger with various tube diameters, fluid flow rates, and cone angles is presented in this paper. Fifteen coils of cone angles 180° (horizontal spiral, 135°, 90°, 45°, and 0° (vertical helical are fabricated and analysed with, same average coil diameter, and tube length, with three different tube diameters. The experimentation is carried out with hot and cold water of flow rate 10 to 100 L per hour (Reynolds range 500 to 5000, and 30 to 90 L per hour, respectively. The temperatures and pressure drop across the heat exchanger are recorded at different mass flow rates of cold and hot fluid. The various parameters: heat transfer coefficient, Nusselt number, effectiveness, and friction factor, are estimated using the temperature, mass flow rate, and pressure drop across the heat exchanger. The analysis indicates that, Nusselt number and friction factor are function of flow rate, tube diameter, cone angle, and curvature ratio. Increase in tube side flow rate increases Nusselt number, whereas it reduces with increase in shell side flow rate. Increase in cone angle and tube diameter, reduces Nusselt number. The effects of cone angle, tube diameter, and fluid flow rates on heat transfer and pressure drop characteristics are detailed in this paper. The empirical correlations are proposed to bring out the physics of the thermal aspects of the conical coil heat exchangers.

  12. Array high-sensitivity room temperature coil system for SNMR detection in shallow depth

    Science.gov (United States)

    Lin, Tingting; Xie, Kunyu; Zhang, Siyuan; Zhao, Jing; Lin, Jun

    2017-01-01

    The noninvasive method of surface nuclear magnetic resonance (SNMR) is a geophysical technique that is directly sensitive to hydrogen protons, besides it can exploit the NMR phenomenon for a quantitative determination of the subsurface groundwater distribution. Traditionally, SNMR utilizes large surface coils for both transmitting excitation pulses and recording the groundwater response. While, in recent research, a low Tc-SQUIDs is taken as a new sensor to replace the large receiving coil (Rx), which performing the best sensitivity for the shallow depth. Nevertheless, SQUID is with the problems of flux trapping and operational difficulties. In this paper, we introduce a room temperature coil system. A Cu coil with diameter of 1 m and a low noise preamplifier was systematically investigated and reached a sensitivity of 0.2fT/Hz1/2.Four preamplifiers are chosen for optimizing the pickup coils. The resolution studies for the array coil systems were performed, and the optimum distance between the adjacent pickup coils to achieve a better experimental results especially for the shallow depth. Our study enable the further use of the room temperature coil for SNMR shallow depth detections.

  13. Electromagnetic characteristics of eccentric figure-eight coils for transcranial magnetic stimulation: A numerical study

    Science.gov (United States)

    Kato, Takuya; Sekino, Masaki; Matsuzaki, Taiga; Nishikawa, Atsushi; Saitoh, Youichi; Ohsaki, Hiroyuki

    2012-04-01

    Repetitive transcranial magnetic stimulation (rTMS) is effective for treatment of several neurological and psychiatric diseases. We proposed an eccentric figure-eight coil, which induces strong eddy currents in the target brain tissue. In this study, numerical analyses were carried out to obtain magnetic field distribution of the eccentric figure-eight coil and eddy current in the brain. The analyses were performed with various coil design parameters, such as the outer and inner diameters and number of turns, to investigate the influence of these parameters on the coil characteristics. Increases in the inner diameter, outer diameter, and number of turns caused increases in the maximum eddy current densities. Coil inductance, working voltage, and heat generation also became higher with the increases in these design parameters. In order to develop a compact stimulator system for use at home, we need to obtain strong eddy current density, keeping the working voltage as low as possible. Our results show that it is effective to enlarge the outer diameter.

  14. Sustainable Consumer Voices

    DEFF Research Database (Denmark)

    Klitmøller, Anders; Rask, Morten; Jensen, Nevena

    2011-01-01

    Aiming to explore how user driven innovation can inform high level design strategies, an in-depth empirical study was carried out, based on data from 50 observations of private vehicle users. This paper reports the resulting 5 consumer voices: Technology Enthusiast, Environmentalist, Design Lover......, Pragmatist and Status Seeker. Expedient use of the voices in creating design strategies is discussed, thus contributing directly to the practice of high level design managers. The main academic contribution of this paper is demonstrating how applied anthropology can be used to generate insights...... into disruptive emergence of product service systems, where quantitative user analyses rely on historical continuation....

  15. The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

    Energy Technology Data Exchange (ETDEWEB)

    Caillat, Christophe; Fish, Alexander [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands); Pefani, Dafni-Eleftheria; Taraviras, Stavros; Lygerou, Zoi [University of Patras, 26505 Rio, Patras (Greece); Perrakis, Anastassis, E-mail: a.perrakis@nki.nl [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands)

    2015-10-31

    The GemC1 coiled-coil structure has subtle differences compared with its homologues Geminin and Idas. Co-expression experiments in cells and biophysical stability analysis of the Geminin-family coiled coils suggest that the GemC1 coiled coil alone is unstable. GemC1, together with Idas and Geminin, an important regulator of DNA-replication licensing and differentiation decisions, constitute a superfamily sharing a homologous central coiled-coil domain. To better understand this family of proteins, the crystal structure of a GemC1 coiled-coil domain variant engineered for better solubility was determined to 2.2 Å resolution. GemC1 shows a less typical coiled coil compared with the Geminin homodimer and the Geminin–Idas heterodimer structures. It is also shown that both in vitro and in cells GemC1 interacts with Geminin through its coiled-coil domain, forming a heterodimer that is more stable that the GemC1 homodimer. Comparative analysis of the thermal stability of all of the possible superfamily complexes, using circular dichroism to follow the unfolding of the entire helix of the coiled coil, or intrinsic tryptophan fluorescence of a unique conserved N-terminal tryptophan, shows that the unfolding of the coiled coil is likely to take place from the C-terminus towards the N-terminus. It is also shown that homodimers show a single-state unfolding, while heterodimers show a two-state unfolding, suggesting that the dimer first falls apart and the helices then unfold according to the stability of each protein. The findings argue that Geminin-family members form homodimers and heterodimers between them, and this ability is likely to be important for modulating their function in cycling and differentiating cells.

  16. Deformation of Linked Polymer Coils

    Institute of Scientific and Technical Information of China (English)

    董朝霞; 李明远; 吴肇亮; 林梅钦

    2003-01-01

    Linked polymer solution (LPS) is defined as the solution of linked polymer coils (LPCs) dispersed in water, composed of low concentration partially hydrolyzed polyacrylamide (HPAM) and aluminum citrate (crosslinker). In the work, the conformational changes of LPCs under different conditions were investigated by the methods of membrane filtering under low pressure, dynamic light scattering and core flooding experiments. The results showed that in some conditions the LPCs could be compressed mechanically to 1/158.5 of their original volume because of relatively lower HPAM cross-linking. The hydration property of LPCs was similar to that of normal polymer coils. The deformation of LPCs was more restricted than that of ordinary polymer coils under the flow shear stress or the shift of hydration equilibrium caused in the variation of the electrolyte concentration which is responsible for the effective plugging in the throats of porous media when LPCs are used for deep diverting.

  17. VoiceRelay: voice key operation using visual basic.

    Science.gov (United States)

    Abrams, Lise; Jennings, David T

    2004-11-01

    Using a voice key is a popular method for recording vocal response times in a variety of language production tasks. This article describes a class module called VoiceRelay that can be easily utilized in Visual Basic programs for voice key operation. This software-based voice key offers the precision of traditional voice keys (although accuracy is system dependent), as well as the flexibility of volume and sensitivity control. However, VoiceRelay is a considerably less expensive alternative for recording vocal response times because it operates with existing PC hardware and does not require the purchase of external response boxes or additional experiment-generation software. A sample project demonstrating implementation of the VoiceRelay class module may be downloaded from the Psychonomic Society Web archive, www.psychonomic.org/archive.

  18. Coil Optimization for HTS Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    for different tape parameters Ici, ni and Ci, where Ici, ni and Ci are critical current, n - value and price of the ith tape respectively and i=1, 2, 3…, further optimization with respect to cost vs. HTS losses has been performed. Allowing for different types of HTS tapes in the coils, a guidance to which tape....... The proposed coil design is optimized with respect to minimizing the perpendicular field while still maximizing the amplitude of fundamental space harmonic. This guarantees the lowest HTS loss density and best utilization of expensive HTS material in the field winding of the SM. Additionally, accounting...

  19. Electromagnetic Gun With Commutated Coils

    Science.gov (United States)

    Elliott, David G.

    1991-01-01

    Proposed electromagnetic gun includes electromagnet coil, turns of which commutated in sequence along barrel. Electrical current fed to two armatures by brushes sliding on bus bars in barrel. Interaction between armature currents and magnetic field from coil produces force accelerating armature, which in turn, pushes on projectile. Commutation scheme chosen so magnetic field approximately coincides and moves with cylindrical region defined by armatures. Scheme has disadvantage of complexity, but in return, enables designer to increase driving magnetic field without increasing armature current. Attainable muzzle velocity increased substantially.

  20. Voice application development for Android

    CERN Document Server

    McTear, Michael

    2013-01-01

    This book will give beginners an introduction to building voice-based applications on Android. It will begin by covering the basic concepts and will build up to creating a voice-based personal assistant. By the end of this book, you should be in a position to create your own voice-based applications on Android from scratch in next to no time.Voice Application Development for Android is for all those who are interested in speech technology and for those who, as owners of Android devices, are keen to experiment with developing voice apps for their devices. It will also be useful as a starting po

  1. Electromagnetic flat sheet forming by spiral type actuator coil

    Science.gov (United States)

    Akbar, S.; Aleem, M. A.; Sarwar, M. N.; Zillohu, A. U.; Awan, M. S.; Haider, A.; Ahmad, Z.; Akhtar, S.; Farooque, M.

    2016-08-01

    Focus of present work is to develop a setup for high strain rate electromagnetic forming of thin aluminum sheets (0.5, 1.0, 1.5 and 2.0 mm) and optimization of forming parameters. Flat spiral coil of 99.9% pure Cu strip (2.5x8.0 mm) with self-inductance 11 μH, 13 no. of turns and resultant outer diameter of 130mm has been fabricated and was coupled to a capacitor bank of energy, voltage and capacitance of 9 kJ, 900 V and 22.8 mF, respectively. To optimize the coil design, a commercially available software FEMM-4.2 was used to simulate the electromagnetic field profile generated by the coils of different pitch but same number of turns. Results of electromagnetic field intensity proposed by simulation agree in close proximity with those of theoretical as well as experimental data. The calculation of electromagnetic force and magnetic couplings between the coil and metal sheet are made. Forming parameters were optimized for different sheet thicknesses. Electromagnetic field intensity's profile plays a principal role in forming of typical shapes and patterns in sheets.

  2. [Two Cases of Ruptured Cerebral Aneurysm Complicated with Delayed Coil Protrusion after Coil Embolization].

    Science.gov (United States)

    Furukawa, Takashi; Ogata, Atsushi; Ebashi, Ryo; Takase, Yukinori; Masuoka, Jun; Kawashima, Masatou; Abe, Tatsuya

    2016-07-01

    We report two cases of delayed coil protrusion after coil embolization for ruptured cerebral aneurysms. Case 1:An 82-year-old woman with a subarachnoid hemorrhage due to a ruptured small anterior communicating artery aneurysm underwent successful coil embolization. Eighteen days after the procedure, coil protrusion from the aneurysm into the right anterior cerebral artery was observed without any symptoms. Further coil protrusion did not develop after 28 days. Case 2:A 78-year-old woman with a subarachnoid hemorrhage due to a ruptured small left middle cerebral artery aneurysm underwent successful coil embolization. Twenty days after the procedure, coil protrusion from the aneurysm into the left middle cerebral artery was observed, with a transient ischemic attack. Further coil protrusion did not develop. Both patients recovered with antithrombotic treatment. Even though delayed coil protrusion after coil embolization is rare, it should be recognized as a long-term complication of coil embolization for cerebral aneurysms.

  3. Effect of Geometrical Asymmetry on the Phase Behavior of Rod-Coil Diblock Copolymers

    Directory of Open Access Journals (Sweden)

    Jingying Yu

    2016-05-01

    Full Text Available The effect of geometrical asymmetry β (described by the length-diameter ratio of rods on the rod-coil diblock copolymer phase behavior is studied by implementation of self-consistent field theory (SCFT in three-dimensional (3D position space while considering the rod orientation on the spherical surface. The phase diagrams at different geometrical asymmetry show that the aspect ratio of rods β influences not only the order-disorder transition (ODT but also the order-order transition (OOT. By exploring the phase diagram with interactions between rods and coils plotted against β, the β effect on the phase diagram is similar to the copolymer composition f. This suggests that non-lamellae structures can be obtained by tuning β, besides f. When the rods are slim compared with the isotropic shape of the coil segment (β is relatively large, the phase behavior is quite different from that of coil-coil diblock copolymers. In this case, only hexagonal cylinders with the coil at the convex side of the interface and lamella phases are stable even in the absence of orientational interaction between rods. The phase diagram is no longer symmetrical about the symmetric copolymer composition and cylinder phases occupy the large area of the phase diagram. The ODT is much lower than that of the coil-coil diblock copolymer system and the triple point at which disordered, cylinder and lamella phases coexist in equilibrium is located at rod composition fR = 0.66. In contrast, when the rods are short and stumpy (β is smaller, the stretching entropy cost of coils can be alleviated and the phase behavior is similar to coil-coil diblocks. Therefore, the hexagonal cylinder phase formed by coils is also found beside the former two structures. Moreover, the ODT may even become a little higher than that of the coil-coil diblock copolymers due to the large interfacial area per chain provided by the stumpy rods, thus compensating the stretching entropy loss of the coils.

  4. Sustainable Consumer Voices

    DEFF Research Database (Denmark)

    Klitmøller, Anders; Rask, Morten; Jensen, Nevena

    2011-01-01

    Aiming to explore how user driven innovation can inform high level design strategies, an in-depth empirical study was carried out, based on data from 50 observations of private vehicle users. This paper reports the resulting 5 consumer voices: Technology Enthusiast, Environmentalist, Design Lover...

  5. Voices of courage

    Directory of Open Access Journals (Sweden)

    Noraida Abdullah Karim

    2007-07-01

    Full Text Available In May 2007 the Women’s Commission for Refugee Women and Children1 presented its annual Voices of Courage awards to three displaced people who have dedicated their lives to promoting economic opportunities for refugee and displaced women and youth. These are their (edited testimonies.

  6. Listen to a voice

    DEFF Research Database (Denmark)

    Hølge-Hazelton, Bibi

    2001-01-01

    Listen to the voice of a young girl Lonnie, who was diagnosed with Type 1 diabetes at 16. Imagine that she is deeply involved in the social security system. She lives with her mother and two siblings in a working class part of a small town. She is at a special school for problematic youth, and he...

  7. Political animal voices

    NARCIS (Netherlands)

    Meijer, E.R.

    2017-01-01

    In this thesis, I develop a theory of political animal voices. The first part of the thesis focuses on non-human animal languages and forming interspecies worlds. I first investigate the relation between viewing language as exclusively human and seeing humans as categorically different from other

  8. Finding a Voice

    Science.gov (United States)

    Stuart, Shannon

    2012-01-01

    Schools have struggled for decades to provide expensive augmentative and alternative communication (AAC) resources for autistic students with communication challenges. Clunky voice output devices, often included in students' individualized education plans, cost about $8,000, a difficult expense to cover in hard times. However, mobile technology is…

  9. the Voice of Tomorrow

    Institute of Scientific and Technical Information of China (English)

    AlanBurdick

    2003-01-01

    Have you heard Mide? Coule be.Mike is a professional reader,and he's everywhere these days. On MapQuest, the Web-based map service,he'll read aloud whatever directions you ask for. If you like to have AOL or Yahoo! e-mail read aloud to you over the phone, that's Mike's voice you 're hearing. Soon

  10. What the voice reveals.

    NARCIS (Netherlands)

    Ko, Sei Jin

    2007-01-01

    Given that the voice is our main form of communication, we know surprisingly little about how it impacts judgment and behavior. Furthermore, the modern advancement in telecommunication systems, such as cellular phones, has meant that a large proportion of our everyday interactions are conducted voca

  11. The Inner Voice

    Science.gov (United States)

    Ridgway, Anthony James

    2009-01-01

    The inner voice- we all know what it is because we all have it and use it when we are thinking or reading, for example. Little work has been done on it in our field, with the notable exception of Brian Tomlinson, but presumably it must be a cognitive phenomenon which is of great importance in thinking, language learning, and reading in a foreign…

  12. Moving beyond Youth Voice

    Science.gov (United States)

    Serido, Joyce; Borden, Lynne M.; Perkins, Daniel F.

    2011-01-01

    This study combines research documenting the benefits of positive relationships between youth and caring adults on a young person's positive development with studies on youth voice to examine the mechanisms through which participation in youth programs contributes to positive developmental outcomes. Specifically, the study explores whether youth's…

  13. Bodies and Voices

    DEFF Research Database (Denmark)

    A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation to the imprisoned, dismembered, remembered...

  14. Voices for Careers.

    Science.gov (United States)

    York, Edwin G.; Kapadia, Madhu

    Listed in this annotated bibliography are 502 cassette tapes of value to career exploration for Grade 7 through the adult level, whether as individualized instruction, small group study, or total class activity. Available to New Jersey educators at no charge, this Voices for Careers System is also available for duplication on request from the New…

  15. What the voice reveals

    NARCIS (Netherlands)

    Ko, Sei Jin

    2007-01-01

    Given that the voice is our main form of communication, we know surprisingly little about how it impacts judgment and behavior. Furthermore, the modern advancement in telecommunication systems, such as cellular phones, has meant that a large proportion of our everyday interactions are conducted voca

  16. Bodies and Voices

    DEFF Research Database (Denmark)

    A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation to the imprisoned, dismembered, remembered...

  17. Coupled Coils, Magnets and Lenz's Law

    Science.gov (United States)

    Thompson, Frank

    2010-01-01

    Great scientists in the past have experimented with coils and magnets. Here we have a variation where coupling occurs between two coils and the oscillatory motion of two magnets to give somewhat surprising results. (Contains 6 figures and 1 footnote.)

  18. Generalization of Helmholtz coil problem

    Directory of Open Access Journals (Sweden)

    Petković Dejan M.

    2015-01-01

    Full Text Available The primary intent of this work is to propose a simple analytical method for designing coil systems for homogeneous and gradient magnetostatic field generation. Coil system consists of two identical coaxial (regular polygonal current loops. In the space between the loops, there is nearly homogeneous or nearly linear distribution of the magnetic field along the axes depending on the currents' direction. First, we derived a suitable, simple and general expression for the magnetic field along the axes due to a polygonal current loop. We emphasize the importance of the role of this expression for further analysis. The total on-axes magnetic field is the result of superposition of the magnetic fields that each loop generates separately. The proper distance between the loops and the current orientation make the system to become either Helmholtz coil or anti-Helmholtz coil. In this paper we give exact, analytical and general expression for this optimal distance that provides the magnetic field to be homogeneous (linear as much as possible. We based our study on Taylor series expansion of the total magnetic field, demanding that the first contaminating term must be canceled, in both, symmetric and asymmetric case.

  19. Rotor assembly including superconducting magnetic coil

    Energy Technology Data Exchange (ETDEWEB)

    Snitchler, Gregory L. (Shrewsbury, MA); Gamble, Bruce B. (Wellesley, MA); Voccio, John P. (Somerville, MA)

    2003-01-01

    Superconducting coils and methods of manufacture include a superconductor tape wound concentrically about and disposed along an axis of the coil to define an opening having a dimension which gradually decreases, in the direction along the axis, from a first end to a second end of the coil. Each turn of the superconductor tape has a broad surface maintained substantially parallel to the axis of the coil.

  20. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

    DEFF Research Database (Denmark)

    Céspedes, Nora; Habel, Catherine; Lopez-Perez, Mary

    2014-01-01

    Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous...

  1. The many types of interhelical ionic interactions in coiled coils - an overview.

    Science.gov (United States)

    Meier, Markus; Stetefeld, Jörg; Burkhard, Peter

    2010-05-01

    Coiled coils represent the most frequent protein oligomerization motif in nature and are involved in many important biological processes. The prototype interhelical ionic interaction for coiled coils described in literature is an i to i+5 ionic interaction from heptad position g to e', but other possible ionic interactions have also been described. Here we use a statistical approach to systematically analyze all high-quality coiled-coil structures in the RCSB protein database for their interhelical ionic interactions. We provide a complete listing of all possible arrangements and analyze the frequency of their occurrence in the primary sequence together with their probability of formation in the quaternary structure of the coiled coils. We show that the classical i to i+5 ionic interaction is indeed characteristic for parallel dimeric and trimeric coiled coils. But we also show that there are many more i to i+2 ionic interactions in parallel tetrameric and pentameric coiled coils, and in antiparallel coiled coils the classical i to i+5 ionic interaction is in none of the oligomerizations states the most frequently observed ionic interaction. We also demonstrate that many ionic interactions involve residues at the core positions that are usually occupied by hydrophobic residues and that such interhelical ionic interactions are a hallmark feature of dimeric coiled coils.

  2. An Experimental Investigation of Hydraulic Jet Fracturing Technology with Coiled Tubing

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    To solve the increasingly serious problem of "many wells, but low productivity" in China, the hydraulic jetting fracturing technology with coiled tubing, as a new measure for effectively improving the production rate of individual well and enhancing oil and gas recovery, merits much attention nowa- days. On the basis of study of the hydraulic jetting fracturing mechanism with coiled tubing and numerical simulation of pressure distribution inside the pores, the mechanism of pressure rise inside the pores caused by the pressure boost action within the jetting pore and the hydraulic isolation action is examined, and the influence of main parameters on the pressure distribution inside the pores is analyzed. 3 kinds of operating methods of hydraulic jetting fracturing with coiled tubing are raised with the tubular diameter of coiled tub- ing as an important feature parameter. According to the experimental study, the fracturing mechanism and computational resuks of numerical simulation are both examined. It is considered that under the same pres- sure drop of jet nozzle, the pressure inside the pores increases with the confining pressure nearly at a line- ar state. When the vertical depth of the borehole is rather big and the rupture pressure of the formation is higher, it is recommended to use higher pressure drop of jet nozzle for achieving better pressure boost and hydraulic isolation effect. For the hydraulic jetting fracturing with coiled tubing, the coiled tubing with tu- bular diameter not less than 50. 8 mm (2 in. ) is usually used.

  3. A Wide Linear Range Eddy Current Displacement Sensor Equipped with Dual-Coil Probe Applied in the Magnetic Suspension Flywheel

    Directory of Open Access Journals (Sweden)

    Tong Wen

    2012-08-01

    Full Text Available The Eddy Current Displacement Sensor (ECDS is widely used in the Magnetic Suspension Flywheel (MSFW to measure the tiny clearance between the rotor and the magnetic bearings. The linear range of the ECDS is determined by the diameter of its probe coil. Wide clearances must be measured in some new MSFWs recently designed for the different space missions, but the coil diameter is limited by some restrictions. In this paper, a multi-channel ECDS equipped with dual-coil probes is proposed to extend the linear range to satisfy the demands of such MSFWs. In order to determine the best configuration of the dual-coil probe, the quality factors of the potential types of the dual-coil probes, the induced eddy current and the magnetic intensity on the surface of the measuring object are compared with those of the conventional single-coil probe. The linear range of the ECDS equipped with the selected dual-coil probe is extended from 1.1 mm to 2.4 mm under the restrictions without adding any cost for additional compensation circuits or expensive coil materials. The effectiveness of the linear range extension ability and the dynamic response of the designed ECDS are confirmed by the testing and the applications in the MSFW.

  4. April 16th : The World Voice Day

    NARCIS (Netherlands)

    Svec, Jan G.; Behlau, Mara

    2007-01-01

    Although the voice is used as an everyday basis of speech, most people realize its importance only when a voice problem arises. Increasing public awareness of the importance of the voice and alertness to voice problems are the main goals of the World Voice Day, which is celebrated yearly on April 16

  5. Risk factors for voice problems in teachers

    NARCIS (Netherlands)

    Kooijman, P. G. C.; de Jong, F. I. C. R. S.; Thomas, G.; Huinck, W.; Donders, R.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  6. You're a What? Voice Actor

    Science.gov (United States)

    Liming, Drew

    2009-01-01

    This article talks about voice actors and features Tony Oliver, a professional voice actor. Voice actors help to bring one's favorite cartoon and video game characters to life. They also do voice-overs for radio and television commercials and movie trailers. These actors use the sound of their voice to sell a character's emotions--or an advertised…

  7. Risk factors for voice problems in teachers

    NARCIS (Netherlands)

    Kooijman, P. G. C.; de Jong, F. I. C. R. S.; Thomas, G.; Huinck, W.; Donders, R.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  8. Risk factors for voice problems in teachers.

    NARCIS (Netherlands)

    Kooijman, P.G.C.; Jong, F.I.C.R.S. de; Thomas, G.; Huinck, W.J.; Donders, A.R.T.; Graamans, K.; Schutte, H.K.

    2006-01-01

    In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints

  9. Design of a shielded coil element of a matrix gradient coil

    Science.gov (United States)

    Jia, Feng; Littin, Sebastian; Layton, Kelvin J.; Kroboth, Stefan; Yu, Huijun; Zaitsev, Maxim

    2017-08-01

    The increasing interest in spatial encoding with non-linear magnetic fields has intensified the need for coils that generates such fields. Matrix coils consisting of multiple coil elements appear to offer a high flexibility in generating customized encoding fields and are particularly promising for localized high resolution imaging applications. However, coil elements of existing matrix coils were primarily designed and constructed for better shimming and therefore are not expected to achieve an optimal performance for local spatial encoding. Moreover, eddy current properties of such coil elements were not fully explored. In this work, an optimization problem is formulated based on the requirement of local non-linear encoding and eddy current reduction that results in novel designs of coil elements for an actively-shielded matrix gradient coil. Two metrics are proposed to assess the performance of different coil element designs. The results are analyzed to reveal new insights into coil element design.

  10. Scaffolds, levers, rods and springs: diverse cellular functions of long coiled-coil proteins.

    Science.gov (United States)

    Rose, A; Meier, I

    2004-08-01

    Long alpha-helical coiled-coil proteins are involved in a variety of organizational and regulatory processes in eukaryotic cells. They provide cables and networks in the cyto- and nucleoskeleton, molecular scaffolds that organize membrane systems, motors, levers, rotating arms and possibly springs. A growing number of human diseases are found to be caused by mutations in long coiled-coil proteins. This review summarizes our current understanding of the multifaceted group of long coiled-coil proteins in the cytoskeleton, nucleus, Golgi and cell division apparatus. The biophysical features of coiled-coil domains provide first clues toward their contribution to the diverse protein functions and promise potential future applications in the area of nanotechnology. Combining the power of fully sequenced genomes and structure prediction algorithms, it is now possible to comprehensively summarize and compare the complete inventory of coiled-coil proteins of different organisms.

  11. Repeats in transforming acidic coiled-coil (TACC) genes.

    Science.gov (United States)

    Trivedi, Seema

    2013-06-01

    Transforming acidic coiled-coil proteins (TACC1, 2, and 3) are essential proteins associated with the assembly of spindle microtubules and maintenance of bipolarity. Dysregulation of TACCs is associated with tumorigenesis, but studies of microsatellite instability in TACC genes have not been extensive. Microsatellite or simple sequence repeat instability is known to cause many types of cancer. The present in silico analysis of SSRs in human TACC gene sequences shows the presence of mono- to hexa-nucleotide repeats, with the highest densities found for mono- and di-nucleotide repeats. Density of repeats is higher in introns than in exons. Some of the repeats are present in regulatory regions and retained introns. Human TACC genes show conservation of many repeat classes. Microsatellites in TACC genes could be valuable markers for monitoring numerical chromosomal aberrations and or cancer.

  12. Space-deployed, thin-walled enclosure for a cryogenically-cooled high temperature superconducting coil

    Science.gov (United States)

    Porter, Allison K.

    The interaction of magnetic fields generated by large superconducting coils has multiple applications in space, including actuation of spacecraft or spacecraft components, wireless power transfer, and shielding of spacecraft from radiation and high energy particles. These applications require coils with major diameters as large as 20 meters and a thermal management system to maintain the superconducting material of the coil below its critical temperature. Since a rigid thermal management system, such as a heat pipe, is unsuitable for compact stowage inside a 5 meter payload fairing, a thin-walled thermal enclosure is proposed. A 1.85 meter diameter test article consisting of a bladder layer for containing chilled nitrogen vapor, a restraint layer, and multilayer insulation was tested in a custom toroidal vacuum chamber. The material properties found during laboratory testing are used to predict the performance of the test article in low Earth orbit. Deployment motion of the same test article was measured using a motion capture system and the results are used to predict the deployment in space. A 20 meter major diameter and coil current of 6.7 MA is selected as a point design case. This design point represents a single coil in a high energy particle shielding system. Sizing of the thermal and structural components of the enclosure is completed. The thermal and deployment performance is predicted.

  13. Coil Migration through a Neuroform 3 Stent during Endovascular Coiling. A Case Report.

    LENUS (Irish Health Repository)

    O'Hare, A

    2009-07-29

    Summary: A 43-year-old woman attended for stent assisted coiling. A Neuroform 30 x 4.5 mm stent had been successfully placed over the left periophthalmic aneurysm. During the coiling the first coil migrated through the crowns in the stent, lodging at the MCA bifurcation. We believe that the coil herniated through the overlying stent due to the carotid siphon curvature and the open cell design. Furthermore the distal markers of the stent impeded coil extraction with a MERCI device.

  14. Formation of the geometrically controlled carbon coils by manipulating the additive gas (SF6) flow rate.

    Science.gov (United States)

    Jeon, Young-Chul; Kim, Sung-Hoon

    2012-07-01

    Carbon coils could be synthesized using C2H2/H2 as source gases and SF6 as an incorporated additive gas under the thermal chemical vapor deposition system. The nickel catalyst layer deposition and then hydrogen plasma pretreatment were performed prior to the carbon coils deposition reaction. The flow rate and the injection time of SF6 varied according to the different reaction processes. Geometries of carbon coils developed from embryos to nanosized coils with increasing SF, flow rate from 5 to 35 sccm under the short SF6 flow injection time (5 minutes) condition. The gradual development of carbon coils geometries from nanosized to microsized types could be observed with increasing SF6 flow rate under the full time (90 minutes) SF6 flow injection condition. The flow rate of SF6 for the coil-type geometry formation should be more than or at least equal to the flow rate of carbon source gas (C2H2). A longer injection time of SF6 flow would increase the size of coils diameters from nanometer to micrometer.

  15. Construction and Evaluation of Rodent-Specific rTMS Coils.

    Science.gov (United States)

    Tang, Alexander D; Lowe, Andrea S; Garrett, Andrew R; Woodward, Robert; Bennett, William; Canty, Alison J; Garry, Michael I; Hinder, Mark R; Summers, Jeffery J; Gersner, Roman; Rotenberg, Alexander; Thickbroom, Gary; Walton, Joseph; Rodger, Jennifer

    2016-01-01

    Rodent models of transcranial magnetic stimulation (TMS) play a crucial role in aiding the understanding of the cellular and molecular mechanisms underlying TMS induced plasticity. Rodent-specific TMS have previously been used to deliver focal stimulation at the cost of stimulus intensity (12 mT). Here we describe two novel TMS coils designed to deliver repetitive TMS (rTMS) at greater stimulation intensities whilst maintaining spatial resolution. Two circular coils (8 mm outer diameter) were constructed with either an air or pure iron-core. Peak magnetic field strength for the air and iron-cores were 90 and 120 mT, respectively, with the iron-core coil exhibiting less focality. Coil temperature and magnetic field stability for the two coils undergoing rTMS, were similar at 1 Hz but varied at 10 Hz. Finite element modeling of 10 Hz rTMS with the iron-core in a simplified rat brain model suggests a peak electric field of 85 and 12.7 V/m, within the skull and the brain, respectively. Delivering 10 Hz rTMS to the motor cortex of anaesthetized rats with the iron-core coil significantly increased motor evoked potential amplitudes immediately after stimulation (n = 4). Our results suggest these novel coils generate modest magnetic and electric fields, capable of altering cortical excitability and provide an alternative method to investigate the mechanisms underlying rTMS-induced plasticity in an experimental setting.

  16. Evaluation of immersion coil designs for natural convection-driven batch cooling or heating in tanks

    Energy Technology Data Exchange (ETDEWEB)

    Joye, Donald D.; Smith, Michael A.

    2000-09-01

    Various designs of immersion coils for batch cooling or heating of liquids in tanks were investigated to determine which design was most efficient. This equipment has direct utility in chemical batch processing operations and, particularly, wort cooling - a critical step in small-scale batch brewing of beer. This operation does not use a stirrer or agitation for a variety of reasons, hence it is dependent on natural-convection mechanisms for heat transfer, yet quick cooling is desired. Four basic coil designs with several permutations were evaluated. The results fell into four groups - best, good, mediocre, and worst performers. We found that coil placement and shape were design parameters that had a critical effect on the rate of cooling. Coil spacing also had a significant effect on the cooling rate when it was less than about 2 diameters. (Author)

  17. Quadrupole gradient coil design and optimization: a printed circuit board approach.

    Science.gov (United States)

    Chu, K; Rutt, B K

    1994-06-01

    Three different dual-axis quadrupole gradient coils for quantitative high resolution MR imaging of small animals, phantoms and specimens were designed and built using printed circuit board technology. Numerical optimization of the conductor positions was used to increase the volume of 0.4% gradient uniformity by up to a factor of four. In one coil, the volume of 5% gradient uniformity occupied 88% and 83% of the overall diameter and length of the coil, respectively. A systematic error of 0.5% in the wire placement was shown to cause a reduction in the volume of 0.4% gradient uniformity by a factor of two, though the region of 5% gradient uniformity was not significantly affected. Heat transfer calculations were used to determine maximum peak and root-mean-squared currents that could safely be applied to the coils.

  18. On the construction of Tesla transformers. Period of oscillation and self-inductance of the coil. (Zur construction von Teslatransformatoren. Schwingungsdauer und Selbstinduction von Drahtspulen)

    CERN Document Server

    Knight, David W

    2016-01-01

    English Translation of Paul Drude's 1902 investigation into the factors affecting the self-resonance of single-layer solenoid coils. The ratio of the self-resonant half-wavelength to the conductor length is is found to be principally dependent on the height-to diameter ratio of the coil and the dielectric constants of any insulating materials involved in the construction.

  19. Detachable Gianturco spring coils to occlude small patent ductus arteriosus. Preliminary results; Occlusione percutanea del dotto di Botallo con spirali di Gianturco con rilascio controllato. Risultati preliminari

    Energy Technology Data Exchange (ETDEWEB)

    Gasparini, Daniele; Basadonna, Pier Tommaso [Azienda Ospedaliera ad alta specializzazione S. Maria della Misericordia, Udine (Italy). Istituto di Radiologia. Modulo di Radiologia vascolare e interventistica; Fontanelli, Alessandro; Bernardi, Guglielmo; Morocutti, Giorgio [Azienda Ospedaliera ad alta specializzazione S. Maria della Misericordia, Udine (Italy). Istituto di Cardiologia. Modulo di Emodinanica e interventistica

    1997-04-01

    Introduction: Botallo`s duct occlusion with Gianturco coils is effective in the fistulas with max diameter of 3.3 mm. The insertion technique does not permit to control coil positioning inside the fistula and the coil itself may migrate to the pulmonary artery. They report their experience with a new system of temporary hookup of the coil proximal end to a metal thread (Cook device) which permits to change the position of the coil or to replace it. Materials and methods: They treated 6 patients with persistence of Botallo`s duct (diameter: 2-3.5 mm, mean: 2.9 mm). The duct was occluded in 5/6 patients. The coil migrated to the pulmonary artery in a case where the hookup system permitted to retrieve and then replace it with too big for the small aorta. No complications were observed. Results: Follow-up chest films at 24 hours showed coil stability and color Doppler US confirmed the occlusion. The patients were discharged after 24 hours. The follow-up at 6 months confirmed the procedure success. Conclusions: The hookup system was effective to control coil positioning and to extract and replace the coils. The effectiveness of this occlusion technique would be improved if a wider range of coil sizes and types were available.

  20. Keyboard With Voice Output

    Science.gov (United States)

    Huber, W. C.

    1986-01-01

    Voice synthesizer tells what key is about to be depressed. Verbal feedback useful for blind operators or where dim light prevents sighted operator from seeing keyboard. Also used where operator is busy observing other things while keying data into control system. Used as training aid for touch typing, and to train blind operators to use both standard and braille keyboards. Concept adapted to such equipment as typewriters, computers, calculators, telephones, cash registers, and on/off controls.

  1. A simulation study on the design of gradient coils in MRI for the imaging area above the patient bed

    Science.gov (United States)

    Hu, Yang; Wang, Qiuliang; Hu, Xinning; Zhu, Xuchen; Crozier, Stuart; Wang, Yaohui; Liu, Feng

    2017-03-01

    A novel method is proposed for the simulation study the design of gradient coils in a magnetic resonance imaging (MRI) system which generate linear magnetic field gradients only in the region above the patient’s bed. In MRI, the gradient coils are usually designed to create linear-varying magnetic gradient fields in a region that is typically described as a diameter of spherical volume (DSV). In practice, the space under the patient’s bed is not used for imaging, but is still treated as part of the design target in conventional approaches. This work proposes a new design scheme in which only the DSV space above the patient’s bed is considered. In the simulation study, the coil patterns have been obtained using a boundary element method (BEM). Compared to conventional gradient coil design methods, the new scheme produces similar fields above the patient’s bed with much sparser wire spacing (for the case tested: the primary layer and shielding layer have 36%/10% and 6%/17% larger wire spacing for X- and Y-gradient coils, respectively). The new design therefore has reduced inductance compared to conventional coils; a reduction of approximately 23% and 11% for the X- and Y-gradient coils, respectively. The resistances of the coils are also reduced. Based on an acoustic analysis, the new gradient coils are slightly quieter (3 dB for the typical operating frequency) than conventional gradient systems.

  2. Performance evaluation of matrix gradient coils.

    Science.gov (United States)

    Jia, Feng; Schultz, Gerrit; Testud, Frederik; Welz, Anna Masako; Weber, Hans; Littin, Sebastian; Yu, Huijun; Hennig, Jürgen; Zaitsev, Maxim

    2016-02-01

    In this paper, we present a new performance measure of a matrix coil (also known as multi-coil) from the perspective of efficient, local, non-linear encoding without explicitly considering target encoding fields. An optimization problem based on a joint optimization for the non-linear encoding fields is formulated. Based on the derived objective function, a figure of merit of a matrix coil is defined, which is a generalization of a previously known resistive figure of merit for traditional gradient coils. A cylindrical matrix coil design with a high number of elements is used to illustrate the proposed performance measure. The results are analyzed to reveal novel features of matrix coil designs, which allowed us to optimize coil parameters, such as number of coil elements. A comparison to a scaled, existing multi-coil is also provided to demonstrate the use of the proposed performance parameter. The assessment of a matrix gradient coil profits from using a single performance parameter that takes the local encoding performance of the coil into account in relation to the dissipated power.

  3. Experimental study on steam-water two-phase flow frictional pressure drops in helical coils

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    Experiments of steam-water two-phase flow frictional pressure drop in a vertical helical coil were carried out in the high-pressure water test loop of Xi'an jiaotong University,The coil is made of stainless steel tube with an inner diameter of 16mm,the helix diameter measured from tube axis to tube axis is 1.3m,and helix angle of the coil is 3.65°,The experimental conditions are:pressurep=4-18MPa,mass velocity G=400-1400kg/(m2.s),inner wall heat flux q=100-700kW/m2,Based on these data,a correlation for predicting the steam-water two-phase flow frictional pressure drop was derived,it can be used for the design of steam generator of HTGR.

  4. Quenching in coupled adiabatic coils

    Energy Technology Data Exchange (ETDEWEB)

    Williams, J.E.C.

    1985-03-01

    The prediction of the effects of a quench on stress and temperature is an important aspect of the design of superconducting magnets. Of particular interest, and the exclusive topic of this study, is the prediction of the effects of quenching in coupled adiabatic coils, such as the multi-section windings of a high field NMR spectrometer magnet. The predictive methods used here are based on the measurement of the time of propagation of quench between turns. From this measurement an approximate algorithum for the propagation time is used in a code which solves the linear differential equations for the coil currents and calculates the movement of normal zone boundaries and hence the associated winding resistance.

  5. Why Is My Voice Changing? (For Teens)

    Science.gov (United States)

    ... Week of Healthy Breakfasts Shyness Why Is My Voice Changing? KidsHealth > For Teens > Why Is My Voice ... deeper than a girl's, though. What Causes My Voice to Change? At puberty, guys' bodies begin producing ...

  6. Common Problems That Can Affect Your Voice

    Science.gov (United States)

    ... near you Common Problems That Can Affect Your Voice Common Problems That Can Affect Your Voice Patient ... that traditionally accompany gastro esophageal reflux disease (GERD). Voice Misuse and Overuse Speaking is a physical task ...

  7. Voice and silence in organizations

    Directory of Open Access Journals (Sweden)

    Moaşa, H.

    2011-01-01

    Full Text Available Unlike previous research on voice and silence, this article breaksthe distance between the two and declines to treat them as opposites. Voice and silence are interrelated and intertwined strategic forms ofcommunication which presuppose each other in such a way that the absence of one would minimize completely the other’s presence. Social actors are not voice, or silence. Social actors can have voice or silence, they can do both because they operate at multiple levels and deal with multiple issues at different moments in time.

  8. VOICE REHABILITATION FOLLOWING TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thiagarajan

    2015-03-01

    Full Text Available Despite continuing advances in surgical management of laryngeal malignancy, total laryngectomy is still the treatment of choice in advanced laryngeal malignancies. Considering the longevity of the patient following total laryngectomy, various measures have been adopted in order to provide voice function to the patient. Significant advancements have taken place in voice rehabilitation of post laryngectomy patients. Advancements in oncological surgical techniques and irradiation techniques have literally cured laryngeal malignancies. Among the various voice rehabilitation techniques available TEP (Tracheo oesophageal puncture is considered to be the gold standard. This article attempts to explore the various voice rehabilitation technique available with primary focus on TEP.

  9. Coiled transmission line pulse generators

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, Kenneth Fox (Columbia, MO)

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  10. The impact of voice on speech realization

    OpenAIRE

    Jelka Breznik

    2014-01-01

    The study discusses spoken literary language and the impact of voice on speech realization. The voice consists of a sound made by a human being using the vocal folds for talking, singing, laughing, crying, screaming… The human voice is specifically the part of human sound production in which the vocal folds (vocal cords) are the primary sound source. Our voice is our instrument and identity card. How does the voice (voice tone) affect others and how do they respond, positively or negatively? ...

  11. Self-correction coil: operation mechanism of self-correction coil

    Energy Technology Data Exchange (ETDEWEB)

    Hosoyama, K.

    1983-06-01

    We discuss here the operation mechanism of self-correction coil with a simple model. At the first stage, for the ideal self-correction coil case we calculate the self-inductance L of self-correction coil, the mutual inductance M between the error field coil and the self-correction coil, and using the model the induced curent in the self-correction coil by the external magnetic error field and induced magnetic field by the self-correction coil. And at the second stage, we extend this calculation method to non-ideal self-correction coil case, there we realize that the wire distribution of self-correction coil is important to get the high enough self-correction effect. For measure of completeness of self-correction effect, we introduce the efficiency eta of self-correction coil by the ratio of induced magnetic field by the self-correction coil and error field. As for the examples, we calculate L, M and eta for two cases; one is a single block approximation of self-correction coil winding and the other is a two block approximation case. By choosing the adequate angles of self-correction coil winding, we can get about 98% efficiency for single block approximation case and 99.8% for two block approximation case. This means that by using the self-correction coil we can improve the field quality about two orders.

  12. Nanofluids heat transfer and flow analysis in vertical spirally coiled tubes using Eulerian two-phase turbulent model

    Science.gov (United States)

    Naphon, P.; Arisariyawong, T.; Nualboonrueng, T.

    2017-07-01

    A computation fluid dynamics study has been performed to analyze the nanofluids heat transfer and flow characteristics in the spirally coiled tubes. Eulerian two-phase turbulent model is applied to simulate the heat transfer and flow characteristics in the vertical spirally coiled tube. The spirally coiled tubes are fabricated by bending a 8.50 mm inner diameter straight copper tube into a spiral-coil with two different curvature ratios of 0.035, 0.060. The predicted results are verified with the present measured data. Reasonable agreement is obtained from the comparison between the measured data and the predicted results. In addition, due to the centrifugal force, the induced secondary flow has significant effect on the heat transfer enhancement as flowing through the spirally coiled tube. Effects of curvature, nanofluids concentration and hot water temperature on the nanofluids heat transfer characteristics and pressure drop are considered.

  13. The Voice Handicap Index with Post-Laryngectomy Male Voices

    Science.gov (United States)

    Evans, Eryl; Carding, Paul; Drinnan, Michael

    2009-01-01

    Background: Surgical treatment for advanced laryngeal cancer involves complete removal of the larynx ("laryngectomy") and initial total loss of voice. Post-laryngectomy rehabilitation involves implementation of different means of "voicing" for these patients wherever possible. There is little information about laryngectomees'…

  14. Pedagogic Voice: Student Voice in Teaching and Engagement Pedagogies

    Science.gov (United States)

    Baroutsis, Aspa; McGregor, Glenda; Mills, Martin

    2016-01-01

    In this paper, we are concerned with the notion of "pedagogic voice" as it relates to the presence of student "voice" in teaching, learning and curriculum matters at an alternative, or second chance, school in Australia. This school draws upon many of the principles of democratic schooling via its utilisation of student voice…

  15. Coiled-coil protein composition of 22 proteomes – differences and common themes in subcellular infrastructure and traffic control

    Directory of Open Access Journals (Sweden)

    Meier Iris

    2005-11-01

    Full Text Available Abstract Background Long alpha-helical coiled-coil proteins are involved in diverse organizational and regulatory processes in eukaryotic cells. They provide cables and networks in the cyto- and nucleoskeleton, molecular scaffolds that organize membrane systems and tissues, motors, levers, rotating arms, and possibly springs. Mutations in long coiled-coil proteins have been implemented in a growing number of human diseases. Using the coiled-coil prediction program MultiCoil, we have previously identified all long coiled-coil proteins from the model plant Arabidopsis thaliana and have established a searchable Arabidopsis coiled-coil protein database. Results Here, we have identified all proteins with long coiled-coil domains from 21 additional fully sequenced genomes. Because regions predicted to form coiled-coils interfere with sequence homology determination, we have developed a sequence comparison and clustering strategy based on masking predicted coiled-coil domains. Comparing and grouping all long coiled-coil proteins from 22 genomes, the kingdom-specificity of coiled-coil protein families was determined. At the same time, a number of proteins with unknown function could be grouped with already characterized proteins from other organisms. Conclusion MultiCoil predicts proteins with extended coiled-coil domains (more than 250 amino acids to be largely absent from bacterial genomes, but present in archaea and eukaryotes. The structural maintenance of chromosomes proteins and their relatives are the only long coiled-coil protein family clearly conserved throughout all kingdoms, indicating their ancient nature. Motor proteins, membrane tethering and vesicle transport proteins are the dominant eukaryote-specific long coiled-coil proteins, suggesting that coiled-coil proteins have gained functions in the increasingly complex processes of subcellular infrastructure maintenance and trafficking control of the eukaryotic cell.

  16. Mosquito coil emissions and health implications.

    Science.gov (United States)

    Liu, Weili; Zhang, Junfeng; Hashim, Jamal H; Jalaludin, Juliana; Hashim, Zailina; Goldstein, Bernard D

    2003-09-01

    Burning mosquito coils indoors generates smoke that can control mosquitoes effectively. This practice is currently used in numerous households in Asia, Africa, and South America. However, the smoke may contain pollutants of health concern. We conducted the present study to characterize the emissions from four common brands of mosquito coils from China and two common brands from Malaysia. We used mass balance equations to determine emission rates of fine particles (particulate matter pollutant concentrations resulting from burning mosquito coils could substantially exceed health-based air quality standards or guidelines. Under the same combustion conditions, the tested Malaysian mosquito coils generated more measured pollutants than did the tested Chinese mosquito coils. We also identified a large suite of volatile organic compounds, including carcinogens and suspected carcinogens, in the coil smoke. In a set of experiments conducted in a room, we examined the size distribution of particulate matter contained in the coil smoke and found that the particles were ultrafine and fine. The findings from the present study suggest that exposure to the smoke of mosquito coils similar to the tested ones can pose significant acute and chronic health risks. For example, burning one mosquito coil would release the same amount of PM(2.5) mass as burning 75-137 cigarettes. The emission of formaldehyde from burning one coil can be as high as that released from burning 51 cigarettes.

  17. Voice and Speech after Laryngectomy

    Science.gov (United States)

    Stajner-Katusic, Smiljka; Horga, Damir; Musura, Maja; Globlek, Dubravka

    2006-01-01

    The aim of the investigation is to compare voice and speech quality in alaryngeal patients using esophageal speech (ESOP, eight subjects), electroacoustical speech aid (EACA, six subjects) and tracheoesophageal voice prosthesis (TEVP, three subjects). The subjects reading a short story were recorded in the sound-proof booth and the speech samples…

  18. Voice Quality of Psychological Origin

    Science.gov (United States)

    Teixeira, Antonio; Nunes, Ana; Coimbra, Rosa Lidia; Lima, Rosa; Moutinho, Lurdes

    2008-01-01

    Variations in voice quality are essentially related to modifications of the glottal source parameters, such as: F[subscript 0], jitter, and shimmer. Voice quality is affected by prosody, emotional state, and vocal pathologies. Psychogenic vocal pathology is particularly interesting. In the present case study, the speaker naturally presented a…

  19. Voice handicap index in Swedish.

    Science.gov (United States)

    Ohlsson, Ann-Christine; Dotevall, Hans

    2009-01-01

    The objective of this study was to evaluate a Swedish version of the voice handicap index questionnaire (Sw-VHI). A total of 57 adult, dysphonic patients and 15 healthy controls completed the Sw-VHI and rated the degree of vocal fatigue and hoarseness on visual analogue scales. A perceptual voice evaluation was also performed. Test-retest reliability was analyzed in 38 subjects without voice complaints. Sw-VHI distinguished between dysphonic subjects and controls (P 0.84) and test-retest reliability (intraclass correlation coefficient >0.75) were good. Only moderate or weak correlations were found between Sw-VHI and the subjective and perceptual voice ratings. The data indicate that a difference above 13 points for the total Sw-VHI score and above 6 points for the Sw-VHI subscales is significant for an individual when comparing two different occasions. In conclusion, the Sw-VHI appears to be a robust instrument for assessment of the psycho-social impact of a voice disorder. However, Sw-VHI seems to, at least partly, capture different aspects of voice function to the subjective voice ratings and the perceptual voice evaluation.

  20. Enhancing Author's Voice through Scripting

    Science.gov (United States)

    Young, Chase J.; Rasinski, Timothy V.

    2011-01-01

    The authors suggest using scripting as a strategy to mentor and enhance author's voice in writing. Through gradual release, students use authentic literature as a model for writing with voice. The authors also propose possible extensions for independent practice, integration across content areas, and tips for evaluation.

  1. Voice, Schooling, Inequality, and Scale

    Science.gov (United States)

    Collins, James

    2013-01-01

    The rich studies in this collection show that the investigation of voice requires analysis of "recognition" across layered spatial-temporal and sociolinguistic scales. I argue that the concepts of voice, recognition, and scale provide insight into contemporary educational inequality and that their study benefits, in turn, from paying attention to…

  2. Voices in History

    Directory of Open Access Journals (Sweden)

    Ivan Leudar

    2001-06-01

    Full Text Available Experiences of “hearing voices” nowadays usually count as verbal hallucinations and they indicate serious mental illness. Some are first rank symptoms of schizophrenia, and the mass media, at least in Britain, tend to present them as antecedents of impulsive violence. They are, however, also found in other psychiatric conditions and epidemiological surveys reveal that even individuals with no need of psychiatric help can hear voices, sometimes following bereavement or abuse, but sometimes for no discernible reason. So do these experiences necessarily mean insanity and violence, and must they be thought of as pathogenic hallucinations; or are there other ways to understand them and live with them, and with what consequences?One way to make our thinking more flexible is to turn to history. We find that hearing voices was always an enigmatic experience, and the people who had it were rare. The gallery of voice hearers is, though, distinguished and it includes Galilei, Bunyan and St Teresa. Socrates heard a daemon who guided his actions, but in his time this did not signify madness, nor was it described as a hallucination. Yet in 19th century French psychological medicine the daemon became a hallucination and Socrates was retrospectively diagnosed as mentally ill. This paper examines the controversies which surrounded the experience at different points in history as well as the practice of retrospective psychiatry. The conclusion reached on the basis of the historical materials is that the experience and the ontological status it is ascribed are not trans-cultural or trans-historic but situated both in history and in the contemporary conflicts.

  3. Usefulness of multifunctional gastrointestinal coil catheter for colorectal stent placement

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae-Hyung; Shin, Ji Hoon; Kim, Jin Hyoung; Lim, Jin-Oh; Kim, Kyung Rae [Asan Medical Center, Radiology and Research Institute of Radiology, Seoul (Korea); Song, Ho-Young [Asan Medical Center - Radiology, Songpa-gu, Seoul (Korea); Park, In Kook [Dongguk University, Life Science, Seoul (Korea); Choi, Eugene K. [Weill Medical College of Cornell University, New York, NY (United States)

    2008-11-15

    The purpose of this study was to evaluate the usefulness of a multifunctional gastrointestinal coil catheter for stent placement in 98 patients with colorectal strictures. The catheter was used in 98 consecutive patients for stent placement in the rectum (n = 24), recto-sigmoid (n = 13), sigmoid (n = 38), descending (n = 6), transverse (n = 11), splenic flexure (n = 3), hepatic flexure (n = 2), and ascending (n = 1) colon. The catheter was made of a stainless steel coil (1.3 mm in inner diameter), a 0.4-mm nitinol wire, a polyolefin tube, and a hemostasis valve. Usefulness of the catheter was evaluated depending on whether the catheter could pass a stricture over a guide wire and whether measurement of the stricture length was possible. The passage of the catheter over a guide wire beyond the stricture was technically successful and well tolerated in 93 (94.9%) of 98 patients. In the failed five patients, it was not possible to negotiate the guide wire due to presence of nearly complete small bowel obstruction. The average length of stricture was 6.15 cm (range, 3 cm to 20 cm) in patients with the colorectal stricture. There were no procedure-related complications. In conclusion, the multifunctional coil catheter seems to be useful in colorectal stent placement. (orig.)

  4. Facing Sound - Voicing Art

    DEFF Research Database (Denmark)

    Lønstrup, Ansa

    2013-01-01

    This article is based on examples of contemporary audiovisual art, with a special focus on the Tony Oursler exhibition Face to Face at Aarhus Art Museum ARoS in Denmark in March-July 2012. My investigation involves a combination of qualitative interviews with visitors, observations of the audienc......´s interactions with the exhibition and the artwork in the museum space and short analyses of individual works of art based on reception aesthetics and phenomenology and inspired by newer writings on sound, voice and listening....

  5. Voice over IP Security

    CERN Document Server

    Keromytis, Angelos D

    2011-01-01

    Voice over IP (VoIP) and Internet Multimedia Subsystem technologies (IMS) are rapidly being adopted by consumers, enterprises, governments and militaries. These technologies offer higher flexibility and more features than traditional telephony (PSTN) infrastructures, as well as the potential for lower cost through equipment consolidation and, for the consumer market, new business models. However, VoIP systems also represent a higher complexity in terms of architecture, protocols and implementation, with a corresponding increase in the potential for misuse. In this book, the authors examine the

  6. Effects on vocal range and voice quality of singing voice training: the classically trained female voice.

    Science.gov (United States)

    Pabon, Peter; Stallinga, Rob; Södersten, Maria; Ternström, Sten

    2014-01-01

    A longitudinal study was performed on the acoustical effects of singing voice training under a given study program, using the voice range profile (VRP). Pretraining and posttraining recordings were made of students who participated in a 3-year bachelor singing study program. A questionnaire that included questions on optimal range, register use, classification, vocal health and hygiene, mixing technique, and training goals was used to rate and categorize self-assessed voice changes. Based on the responses, a subgroup of 10 classically trained female voices was selected, which was homogeneous enough for effects of training to be identified. The VRP perimeter contour was analyzed for effects of voice training. Also, a mapping within the VRP of voice quality, as expressed by the crest factor, was used to indicate the register boundaries and to monitor the acoustical consequences of the newly learned vocal technique of "mixed voice." VRPs were averaged across subjects. Findings were compared with the self-assessed vocal changes. Pre/post comparison of the average VRPs showed, in the midrange, (1) a decrease in the VRP area that was associated with the loud chest voice, (2) a reduction of the crest factor values, and (3) a reduction of maximum sound pressure level values. The students' self-evaluations of the voice changes appeared in some cases to contradict the VRP findings. VRPs of individual voices were seen to change over the course of a singing education. These changes were manifest also in the average group. High-resolution computerized recording, complemented with an acoustic register marker, allows a meaningful assessment of some effects of training, on an individual basis and for groups that comprise singers of a specific genre. It is argued that this kind of investigation is possible only within a focused training program, given by a faculty who has agreed on the goals. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  7. The coiled coils of cohesin are conserved in animals, but not in yeast.

    Directory of Open Access Journals (Sweden)

    Glenn E White

    Full Text Available BACKGROUND: The SMC proteins are involved in DNA repair, chromosome condensation, and sister chromatid cohesion throughout Eukaryota. Long, anti-parallel coiled coils are a prominent feature of SMC proteins, and are thought to serve as spacer rods to provide an elongated structure and to separate domains. We reported recently that the coiled coils of mammalian condensin (SMC2/4 showed moderate sequence divergence (approximately 10-15% consistent with their functioning as spacer rods. The coiled coils of mammalian cohesins (SMC1/3, however, were very highly constrained, with amino acid sequence divergence typically <0.5%. These coiled coils are among the most highly conserved mammalian proteins, suggesting that they make extensive contacts over their entire surface. METHODOLOGY/PRINCIPAL FINDINGS: Here, we broaden our initial analysis of condensin and cohesin to include additional vertebrate and invertebrate organisms and multiple species of yeast. We found that the coiled coils of SMC1/3 are highly constrained in Drosophila and other insects, and more generally across all animal species. However, in yeast they are no more constrained than the coils of SMC2/4 and Ndc80/Nuf2p, suggesting that they are serving primarily as spacer rods. CONCLUSIONS/SIGNIFICANCE: SMC1/3 functions for sister chromatid cohesion in all species. Since its coiled coils apparently serve only as spacer rods in yeast, it is likely that this is sufficient for sister chromatid cohesion in all species. This suggests an additional function in animals that constrains the sequence of the coiled coils. Several recent studies have demonstrated that cohesin has a role in gene expression in post-mitotic neurons of Drosophila, and other animal cells. Some variants of human Cornelia de Lange Syndrome involve mutations in human SMC1/3. We suggest that the role of cohesin in gene expression may involve intimate contact of the coiled coils of SMC1/3, and impose the constraint on sequence

  8. Optimum coil insertion speed of various coils in brain aneurysm embolization in vitro.

    Science.gov (United States)

    Konishi, Yoshifumi; Takeuchi, Masataka; Fukasaku, Kazuaki

    2016-10-01

    A coil must comprise material with shape memory to perform optimal coil embolization. To achieve this, the alloy characteristics of the coil (hardness, shape, and thickness) must be understood. In this experiment, a catheter was fixed in the bright position and the movement of the coil was observed under a constant rate of insertion; the optimal insertion rate during clinical use was investigated. The first coil insertion speed was evaluated using simulated aneurysms in an in vivo arterial model. The results showed that the insertion force relates to the deployment shape of the coil, that the feedback through the force indicator using sound is very effective, and that the recorder is useful for analysis of coil embolization. The inserted coils during aneurysm embolization were able to wind uniformly within the aneurysm due to a variety of factors (guiding or micro-catheter position and kick-back phenomenon such as delivery wire). Optimal speed is achieved with proper coil design, which allows the coil to be inserted into the aneurysm. The shape and size of the aneurysm can help determine the necessary size and design of the coil that should be used during the optimal speed range. Aneurysm wall and coil characteristics are considered, along with the friction state of the coil (hardness, shape, and thickness), leading to improvements in safety during the insertion procedure at optimum speed.

  9. Questioning Photovoice Research: Whose Voice?

    Science.gov (United States)

    Evans-Agnew, Robin A; Rosemberg, Marie-Anne S

    2016-07-01

    Photovoice is an important participatory research tool for advancing health equity. Our purpose is to critically review how participant voice is promoted through the photovoice process of taking and discussing photos and adding text/captions. PubMed, Scopus, PsycINFO, and Web of Science databases were searched from the years 2008 to 2014 using the keywords photovoice, photonovella, photovoice and social justice, and photovoice and participatory action research. Research articles were reviewed for how participant voice was (a) analyzed, (b) exhibited in community forums, and (c) disseminated through published manuscripts. Of 21 studies, 13 described participant voice in the data analysis, 14 described participants' control over exhibiting photo-texts, seven manuscripts included a comprehensive set of photo-texts, and none described participant input on choice of manuscript photo-texts. Photovoice designs vary in the advancement of participant voice, with the least advancement occurring in manuscript publication. Future photovoice researchers should expand approaches to advancing participant voice.

  10. Voice quality of psychological origin.

    Science.gov (United States)

    Teixeira, Antonio; Nunes, Ana; Coimbra, Rosa Lídia; Lima, Rosa; Moutinho, Lurdes

    2008-01-01

    Variations in voice quality are essentially related to modifications of the glottal source parameters, such as: F0, jitter, and shimmer. Voice quality is affected by prosody, emotional state, and vocal pathologies. Psychogenic vocal pathology is particularly interesting. In the present case study, the speaker naturally presented a ventricular band voice whereas in a controlled production he was able to use a more normal phonation process. A small corpus was recorded which included sustained vowels and short sentences in both registers. A normal speaker was also recorded in similar tasks. Annotation and extraction of parameters were made using Praat's voice report function. Application of the Hoarseness Diagram to sustained productions situates this case in the pseudo-glottic phonation region. Analysis of several different parameters related to F0, jitter, shimmer, and harmonicity revealed that the speaker with psychogenic voice was capable of controlling certain parameters (e.g. F0 maximum) but was unable to correct others such as shimmer.

  11. Unusually Stable Helical Coil Allotrope of Phosphorus.

    Science.gov (United States)

    Liu, Dan; Guan, Jie; Jiang, Jingwei; Tománek, David

    2016-12-14

    We have identified an unusually stable helical coil allotrope of phosphorus. Our ab initio density functional theory calculations indicate that the uncoiled, isolated straight one-dimensional chain is equally stable as a monolayer of black phosphorus dubbed phosphorene. The coiling tendency and the attraction between adjacent coil segments add an extra stabilization energy of ∼12 meV/atom to the coil allotrope, similar in value to the ∼16 meV/atom interlayer attraction in bulk black phosphorus. Thus, the helical coil structure is essentially as stable as black phosphorus, the most stable phosphorus allotrope known to date. With an optimum radius of 2.4 nm, the helical coil of phosphorus may fit well and even form inside wide carbon nanotubes.

  12. The Golgin Family of Coiled-Coil Tethering Proteins

    Directory of Open Access Journals (Sweden)

    Tomasz M Witkos

    2016-01-01

    Full Text Available The golgins are a family of predominantly coiled-coil proteins that are localized to the Golgi apparatus. Golgins are present in all eukaryotes, suggesting an evolutionary conserved function. Golgins are anchored to the Golgi membrane by their carboxy terminus and are predicted to adopt an extended conformation that projects into the surrounding cytoplasm. This arrangement is ideal for the capture or tethering of nearby membranes or cytoskeletal elements. Golgin-mediated tethering is thought to be important for vesicular traffic at the Golgi apparatus, the maintenance of Golgi architecture, as well as the positioning of the Golgi apparatus within cells. In addition to acting as tethers, some golgins can also sequester various factors at the Golgi membrane, allowing for the spatiotemporal regulation of downstream cellular functions. Although it is now established that golgins are membrane and cytoskeleton tethers, the mechanisms underlying tethering remain poorly defined. Moreover, the importance of golgin-mediated tethering in a physiological context remains to be fully explored. This review will describe our current understanding of golgin function, highlighting recent progress that has been made, and goes on to discuss outstanding questions and potential avenues for future research with regard to this family of conserved Golgi-associated proteins.

  13. Force modulated conductance of artificial coiled-coil protein monolayers.

    Science.gov (United States)

    Atanassov, Alexander; Hendler, Ziv; Berkovich, Inbal; Ashkenasy, Gonen; Ashkenasy, Nurit

    2013-01-01

    Studies of charge transport through proteins bridged between two electrodes have been the subject of intense research in recent years. However, the complex structure of proteins makes it difficult to elucidate transport mechanisms, and the use of simple peptide oligomers may be an over simplified model of the proteins. To bridge this structural gap, we present here studies of charge transport through artificial parallel coiled-coil proteins conducted in dry environment. Protein monolayers uniaxially oriented at an angle of ∼ 30° with respect to the surface normal were prepared. Current voltage measurements, obtained using conductive-probe atomic force microscopy, revealed the mechano-electronic behavior of the protein films. It was found that the low voltage conductance of the protein monolayer increases linearly with applied force, mainly due to increase in the tip contact area. Negligible compression of the films for loads below 26 nN allowed estimating a tunneling attenuation factor, β(0) , of 0.5-0.6 Å(-1) , which is akin to charge transfer by tunneling mechanism, despite the comparably large charge transport distance. These studies show that mechano-electronic behavior of proteins can shed light on their complex charge transport mechanisms, and on how these mechanisms depend on the detailed structure of the proteins. Such studies may provide insightful information on charge transfer in biological systems.

  14. Muscular tension and body posture in relation to voice handicap and voice quality in teachers with persistent voice complaints.

    NARCIS (Netherlands)

    Kooijman, P.G.C.; Jong, F.I.C.R.S. de; Oudes, M.J.; Huinck, W.J.; Acht, H. van; Graamans, K.

    2005-01-01

    The aim of this study was to investigate the relationship between extrinsic laryngeal muscular hypertonicity and deviant body posture on the one hand and voice handicap and voice quality on the other hand in teachers with persistent voice complaints and a history of voice-related absenteeism. The st

  15. Comparison of three formulations for eddy-current problems in a spiral coil electromagnetic acoustic transducer

    Institute of Scientific and Technical Information of China (English)

    石文泽; 吴运新; 龚海; 赵志然; 范吉志; 谭良辰

    2016-01-01

    Three differential equations based on different definitions of current density are compared. FormulationⅠ is based on an incomplete equation for total current density (TCD). FormulationsⅡ andⅢ are based on incomplete and complete equations for source current density (SCD), respectively. Using the weak form of finite element method (FEM), three formulations were applied in a spiral coil electromagnetic acoustic transducer (EMAT) example to solve magnetic vector potential (MVP). The input impedances calculated by Formulation III are in excellent agreement with the experimental measurements. Results show that the errors for Formulations I & II vary with coil diameter, coil spacing, lift-off distance and external excitation frequency, for the existence of eddy-current and skin & proximity effects. And the current distribution across the coil conductor also follows the same trend. It is better to choose Formulation I instead of Formulation III to solve MVP when the coil diameter is less than twice the skin depth for Formulation I is a low cost and high efficiency calculation method.

  16. A procedure for combining rotating-coil measurements of large-aperture accelerator magnets

    Energy Technology Data Exchange (ETDEWEB)

    Köster, Oliver, E-mail: oliver.koester@cern.ch; Fiscarelli, Lucio, E-mail: lucio.fiscarelli@cern.ch; Russenschuck, Stephan, E-mail: stephan.russenschuck@cern.ch

    2016-05-11

    The rotating search coil is a precise and widely used tool for measuring the magnetic field harmonics of accelerator magnets. This paper deals with combining several such multipole measurements, in order to cover magnet apertures largely exceeding the diameter of the available search coil. The method relies on the scaling laws for multipole coefficients and on the method of analytic continuation along zero-homotopic paths. By acquiring several measurements of the integrated magnetic flux density at different transverse positions within the bore of the accelerator magnet, the uncertainty on the field harmonics can be reduced at the expense of tight tolerances on the positioning. These positioning tolerances can be kept under control by mounting the rotating coil and its motor-drive unit on precision alignment stages. Therefore, the proposed technique is able to yield even more precise results for the higher-order field components than a dedicated rotating search coil of larger diameter. Moreover, the versatility of the measurement bench is enhanced by avoiding the construction of rotating search coils of different measurement radii.

  17. An Experimental Study on Constraint Cooling Process of Hot-rolled CoilS

    Institute of Scientific and Technical Information of China (English)

    Lijuan WANG; Chunli ZHANG

    2003-01-01

    In order to master mechanical property, surface quality and microstructure of constraint cooling (CC) coils undervarious water cooling parameters, more than 100 coils cooling experiments were done with real production process,of which is designed a coolin

  18. Transport vesicle tethering at the trans Golgi network: coiled coil proteins in action

    Directory of Open Access Journals (Sweden)

    Pak-yan Patricia Cheung

    2016-03-01

    Full Text Available The Golgi complex is decorated with so-called Golgin proteins that share a common feature: a large proportion of their amino acid sequences are predicted to form coiled-coil structures. The possible presence of extensive coiled coils implies that these proteins are highly elongated molecules that can extend a significant distance from the Golgi surface. This property would help them to capture or trap inbound transport vesicles and to tether Golgi mini-stacks together. This review will summarize our current understanding of coiled coil tethers that are needed for the receipt of transport vesicles at the trans Golgi network. How do long tethering proteins actually catch vesicles? Golgi-associated, coiled coil tethers contain numerous binding sites for small GTPases, SNARE proteins, and vesicle coat proteins. How are these interactions coordinated and are any or all of them important for the tethering process? Progress towards understanding these questions and remaining, unresolved mysteries will be discussed.

  19. Bodies, Spaces, Voices, Silences

    Directory of Open Access Journals (Sweden)

    Donatella Mazzoleni

    2013-07-01

    Full Text Available A good architecture should not only allow functional, formal and technical quality for urban spaces, but also let the voice of the city be perceived, listened, enjoyed. Every city has got its specific sound identity, or “ISO” (R. O. Benenzon, made up of a complex texture of background noises and fluctuation of sound figures emerging and disappearing in a game of continuous fadings. For instance, the ISO of Naples is characterized by a spread need of hearing the sound return of one’s/others voices, by a hate of silence. Cities may fall ill: illness from noise, within super-crowded neighbourhoods, or illness from silence, in the forced isolation of peripheries. The proposal of an urban music therapy denotes an unpublished and innovative enlarged interdisciplinary research path, where architecture, music, medicine, psychology, communication science may converge, in order to work for rebalancing spaces and relation life of the urban collectivity, through the care of body and sound dimensions.

  20. A new design method for asymmetrical head gradient coils used for superconducting MRI scanner

    Institute of Scientific and Technical Information of China (English)

    TANG Xin; ZU Donglin; BAO Shanglian

    2004-01-01

    A novel approach of asymmetrical gradient coil design for head imaging in MRI (magnetic resonance imaging) is presented in this paper. The design is based on a modified target field method in which the stream function is introduced to replace Blaine's scheme for the length control. The transverse head coil calculated by this method has a high performance. The coil efficiency is 0.41 mT/m/A and the inductance is 512 μH. The coil has an inner diameter of 32 cm and a length of 45.8 cm. The size of the ROU (region of uniformity) is 20 cm along the transverse direction and 17 cm along the axial direction and it is close to one end of the coil. The ROU of the coil matches the ROI (region of interest) of human head very well. Compared with previous designs, our design has relatively high performance and the overlap between the ROU and the ROI is larger (the overlap percent is 95 % ).

  1. Magnetometer utilizing SQUID pico-voltmeter and cooled normal pickup coil

    Energy Technology Data Exchange (ETDEWEB)

    Yang, T.Q. [Research Institute of Superconductor Science and Systems, Kyushu University, Higashi-ku, Hakozaki 6-10-1, Fukuoka 812-8581 (Japan); Yao, Kenichiro [Research Institute of Superconductor Science and Systems, Kyushu University, Higashi-ku, Hakozaki 6-10-1, Fukuoka 812-8581 (Japan); Yamasaki, Daisuke [Research Institute of Superconductor Science and Systems, Kyushu University, Higashi-ku, Hakozaki 6-10-1, Fukuoka 812-8581 (Japan); Enpuku, Keiji [Research Institute of Superconductor Science and Systems, Kyushu University, Higashi-ku, Hakozaki 6-10-1, Fukuoka 812-8581 (Japan)]. E-mail: enpuku@sc.kyushu-u.ac.jp

    2005-10-01

    Magnetometer utilizing a high-T {sub c} SQUID pico-voltometer and cooled normal pickup coil has been developed. The pickup coil was made of copper wire, and cooled to T = 77 K in order to decrease thermal noise from resistance. Total voltage noise of the SQUID pico-voltmeter with a cooled pickup coil was 124 pV/Hz{sup 1/2} and 96 pV/Hz{sup 1/2} at 100 Hz and 1 kHz, respectively, when resistance of the coil was 1.5 {omega}. The magnetic field noise of the magnetometer was 130 pT/Hz{sup 1/2} and 10 pT/Hz{sup 1/2} at 100 Hz and 1 kHz for the pickup coil with 4.4 mm diameter, respectively. Application of the magnetometer to non-destructive evaluation was presented. It is shown that small crack inside Cu plate can be detected with this system in unshielded environment. It was also shown that scanning of the pickup coil in unshielded environment is possible without degradation of the system performance.

  2. The Effect of the Capillary Tube Coil Number on the Refrigeration System Performance

    Directory of Open Access Journals (Sweden)

    Thamir K. Salim

    2012-06-01

    Full Text Available The capillary tube performance for (R134a is experimentally investigated. The experimental setup is a real vapor compression refrigeration system. All properties of the refrigeration system are measured for various mass flow rate from (13 – 23 kg/hr and capillary tube coil number (0-4 with fixed length (150 cm and capillary diameter(2.5mm.The results showed that the theoretical compression power increases by (65.8 % as the condenser temperature increases by (2.71%, also the theoretical compression power decreases by (10.3 % as the capillary tube coil number increases.The study shows also that the cooling capacity increases by (65.3% as the evaporator temperature increases by (8.4 %, and the cooling capacity increases by (1.6%as the capillary tube coil number increases in the range (0-4.The coefficient of performance decreases by (43.4 %, as the mass flow rateincreases by (76.9%, also the coefficient of performance increases by (13.51 % as thecapillary tube coil number increases in the range (0-4.Through this study, it was found that the best coil number in refrigeration cycle at the lowest mass flow rate (31 Kg/hr and at high mass flow rate (23 Kg/hr is (coil number = 4, this will give the highest performance, cooling capacity and lowest theoretical compression power.

  3. Test of Optimized 120-mm LARP $Nb_{3}S_n$ Quadrupole Coil Using Magnetic Mirror Structure

    CERN Document Server

    Chlachidze, G; Andreev, N; Anerella, M; Barzi, E; Bossert, R; Caspi, S; Cheng, D; Dietderich, D; Felice, H; Ferracin, P; Ghosh, A; Godeke, A; Hafalia, A R; Kashikhin, V V; Lamm, M; Marchevsky, M; Nobrega, A; Novitski, I; Orris, D; Sabbi, G L; Schmalzle, J; Wanderer, P; Zlobin, A V

    2013-01-01

    The US LHC accelerator research program (LARP) is developing a new generation of large - aperture high - field quadrupoles based on Nb 3 Sn conductor for the High luminosity upgrade of Large Hadron Collider (HiLumi - LHC). Tests of the first series of 120 - mm aperture HQ coils revealed the necessity for further optimization of the coil design and fabrication process. Modifications in coil design were gradually implemented in two HQ coils previously tested at Fermi National Accelerato r Laboratory (Fermilab) using a magnetic mirror structure (HQM01 and HQM02). This paper describes the construction and test of an HQ mirror model with a coil of optimized design and with an interlayer resistive core in the conductor. The cable for this co il was made of a smaller diameter strand, providing more room for coil expansion during reaction. The 0.8 - mm strand, used in all previous HQ coils was replaced with a 0.778 - mm Nb 3 Sn strand of RRP 108/127 sub - element design. The coil was instrumented with voltage taps, h...

  4. Crossing Cultures with Multi-Voiced Journals

    Science.gov (United States)

    Styslinger, Mary E.; Whisenant, Alison

    2004-01-01

    In this article, the authors discuss the benefits of using multi-voiced journals as a teaching strategy in reading instruction. Multi-voiced journals, an adaptation of dual-voiced journals, encourage responses to reading in varied, cultured voices of characters. It is similar to reading journals in that they prod students to connect to the lives…

  5. Superconducting Coil of Po Dipole

    CERN Multimedia

    1983-01-01

    The Po superconducting dipole was built as a prototype beam transport magnet for the SPS extracted proton beam P0. Its main features were: coil aperture 72 mm, length 5 m, room-temperature yoke, NbTi cable conductor impregnated with solder, nominal field 4.2 T at 4.7 K (87% of critical field). It reached its nominal field without any quench.After this successful test up to its nominal field of 4.2 T, the power was not raised to reach a quench. The magnet was not installed in a beam and had no other further use. Nevertheless its construction provided knowledges and experience which became useful in the design and construction of the LHC magnets. The photo shows a detail of the inner layer winding before superposing the outer layer to form the complete coil of a pole. Worth noticing is the interleaved glass-epoxy sheet (white) with grooved channels for the flow of cooling helium. See also 8211532X.

  6. Promoted-Combustion Chamber with Induction Heating Coil

    Science.gov (United States)

    Richardson, Erin; Hagood, Richard; Lowery, Freida; Herald, Stephen

    2006-01-01

    An improved promoted-combustion system has been developed for studying the effects of elevated temperatures on the flammability of metals in pure oxygen. In prior promoted-combustion chambers, initial temperatures of metal specimens in experiments have been limited to the temperatures of gas supplies, usually near room temperature. Although limited elevated temperature promoted-combustion chambers have been developed using water-cooled induction coils for preheating specimens, these designs have been limited to low-pressure operation due to the hollow induction coil. In contrast, the improved promoted-combustion chamber can sustain a pressure up to 10 kpsi (69 MPa) and, through utilization of a solid induction coil, is capable of preheating a metal specimen up to its melting point [potentially in excess of 2,000 F (approximately equal to 1,100 C)]. Hence, the improved promoted combustion chamber makes a greater range of physical conditions and material properties accessible for experimentation. The chamber consists of a vertical cylindrical housing with an inner diameter of 8 in. (20.32 cm) and an inner height of 20.4 in. (51.81 cm). A threaded, sealing cover at one end of the housing can be unscrewed to gain access for installing a specimen. Inlet and outlet ports for gases are provided. Six openings arranged in a helical pattern in the chamber wall contain sealed sapphire windows for viewing an experiment in progress. The base of the chamber contains pressure-sealed electrical connectors for supplying power to the induction coil. The connectors feature a unique design that prevents induction heating of the housing and the pressure sealing surfaces; this is important because if such spurious induction heating were allowed to occur, chamber pressure could be lost. The induction coil is 10 in. (25.4 cm) long and is fitted with a specimen holder at its upper end. At its lower end, the induction coil is mounted on a ceramic base, which affords thermal insulation to

  7. Comparison of CT and MRI artefacts from coils and vascular plugs used for portal vein embolization

    Energy Technology Data Exchange (ETDEWEB)

    Geisel, Dominik, E-mail: dominik.geisel@charite.de [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Gebauer, Bernhard [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Malinowski, Maciej; Stockmann, Martin [Department of General, Visceral and Transplantation Surgery, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Denecke, Timm [Department of Diagnostic and Interventional Radiology, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany)

    2014-04-15

    Purpose: To retrospectively analyze the degree of artefacts in CT and MRI scans caused by coils and vascular plugs used for portal vein embolization (PVE). Materials and methods: All patients who underwent PVE between July 2011 and December 2012 and received either plug or coil embolization additional to particle embolization were retrospectively analyzed. Artefacts causes by embolization materials were measured in CT and MRI scans following PVE. Results: The sum of the artefact diameters caused from coils was significantly higher in CT (188.3 ± 26.1 mm) than in MRI T1 (50.5 ± 6.5 mm) or T2 imaging (39.5 ± 9.7 mm) (P < 0.05). In MRI, the diameter in T1 and T2 sequences did not differ significantly (P = 0.977). The sum of the artefact diameters from vascular plugs in MRI T1 sequences (62.5 ± 8.7 mm) was significantly higher than in CT (46.6 ± 4.8 mm; P < 0.05) and MRI T2 sequences (52.8 ± 3.8 mm; P < 0.05). Conclusion: PVE with particles and vascular plug causes significantly fewer artefacts than PVE with particles and coils on CT scans following embolization, which can be important in the event of vascular complications or in follow-up scans, should the patient become unresectable.

  8. Multicoil2: predicting coiled coils and their oligomerization states from sequence in the twilight zone.

    Directory of Open Access Journals (Sweden)

    Jason Trigg

    Full Text Available The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices of coiled coils in protein sequences. Multicoil2 combines the pairwise correlations of the previous Multicoil method with the flexibility of Hidden Markov Models (HMMs in a Markov Random Field (MRF. The resulting algorithm integrates sequence features, including pairwise interactions, through multinomial logistic regression to devise an optimized scoring function for distinguishing dimer, trimer and non-coiled-coil oligomerization states; this scoring function is used to produce Markov Random Field potentials that incorporate pairwise correlations localized in sequence. Multicoil2 significantly improves both coiled-coil detection and dimer versus trimer state prediction over the original Multicoil algorithm retrained on a newly-constructed database of coiled-coil sequences. The new database, comprised of 2,105 sequences containing 124,088 residues, includes reliable structural annotations based on experimental data in the literature. Notably, the enhanced performance of Multicoil2 is evident when tested in stringent leave-family-out cross-validation on the new database, reflecting expected performance on challenging new prediction targets that have minimal sequence similarity to known coiled-coil families. The Multicoil2 program and training database are available for download from http://multicoil2.csail.mit.edu.

  9. Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Jeremy D., E-mail: jwilbur@msg.ucsf.edu [Graduate Program in Biophysics, University of California, San Francisco, California 94143 (United States); Hwang, Peter K. [Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143 (United States); Brodsky, Frances M. [The G. W. Hooper Foundation, Departments of Microbiology and Immunology and of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 (United States); Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 (United States); Fletterick, Robert J. [Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143 (United States); Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 (United States); Graduate Program in Biophysics, University of California, San Francisco, California 94143 (United States)

    2010-03-01

    Variable packing interaction related to the conformational flexibility within the huntingtin-interacting protein 1 coiled coil domain. Huntingtin-interacting protein 1 (HIP1) is an important link between the actin cytoskeleton and clathrin-mediated endocytosis machinery. HIP1 has also been implicated in the pathogenesis of Huntington’s disease. The binding of HIP1 to actin is regulated through an interaction with clathrin light chain. Clathrin light chain binds to a flexible coiled-coil domain in HIP1 and induces a compact state that is refractory to actin binding. To understand the mechanism of this conformational regulation, a high-resolution crystal structure of a stable fragment from the HIP1 coiled-coil domain was determined. The flexibility of the HIP1 coiled-coil region was evident from its variation from a previously determined structure of a similar region. A hydrogen-bond network and changes in coiled-coil monomer interaction suggest that the HIP1 coiled-coil domain is uniquely suited to allow conformational flexibility.

  10. First qualification of ITER Toroidal Field Coil conductor jacketing

    Energy Technology Data Exchange (ETDEWEB)

    Hamada, Kazuya, E-mail: hamada.kazuya@jaea.go.jp [Japan Atomic Energy Agency (Japan); Takahashi, Yoshikazu; Isono, Takaaki; Nunoya, Yoshihiko; Matsui, Kunihiro; Kawano, Katsumi; Oshikiri, Masayuki; Tsutsumi, Fumiaki; Koizumi, Norikiyo; Nakajima, Hideo; Okuno, Kiyoshi [Japan Atomic Energy Agency (Japan); Matsuda, Hidemitsu; Yano, Yoshitaka [Nippon Steel Engineering Co. Ltd (Japan); Devred, Arnauld; Bessette, Denis [ITER Organization (France)

    2011-10-15

    The Japan Atomic Energy Agency (JAEA) has the responsibility to procure 25% of the ITER Toroidal Field Coil conductors as the Japanese Domestic Agency (JADA) in the ITER project. The TF conductor is a circular shaped, cable-in-conduit conductor, composed of a cable and a stainless steel conduit (jacket). The outer diameter and maximum length of the TF conductor are 43.7 mm and 760 m, respectively. JAEA started to produce strand, cables and jacket sections and to construct a conductor manufacturing (jacketing) facility in 2008. Following preparation in December 2009 of the jacketing facility, the dummy cable, the jacket sections and fabrication procedures, such as welding, cable insertion, compaction and spooling, JAEA manufactured a 760 m long Cu dummy conductor for process qualification. Into the 760 m long Cu dummy conductor jacketing, JAEA successfully inserted the cable with a maximum force of 32 kN. The outer diameter of the cross section of the spooled conductor was 43.7 {+-} 0.15 mm, which complies with the ITER target requirement of 43.7 {+-} 0.3 mm. Following qualification of all manufacturing processes, JAEA has started to fabricate superconducting conductors for the TF coils.

  11. Advanced Mud System for Microhole Coiled Tubing Drilling

    Energy Technology Data Exchange (ETDEWEB)

    Kenneth Oglesby

    2008-12-01

    An advanced mud system was designed and key components were built that augment a coiled tubing drilling (CTD) rig that is designed specifically to drill microholes (less than 4-inch diameter) with advanced drilling techniques. The mud system was tailored to the hydraulics of the hole geometries and rig characteristics required for microholes and is capable of mixing and circulating mud and removing solids while being self contained and having zero discharge capability. Key components of this system are two modified triplex mud pumps (High Pressure Slurry Pumps) for advanced Abrasive Slurry Jetting (ASJ) and a modified Gas-Liquid-Solid (GLS) Separator for well control, flow return and initial processing. The system developed also includes an additional component of an advanced version of ASJ which allows cutting through most all materials encountered in oil and gas wells including steel, cement, and all rock types. It includes new fluids and new ASJ nozzles. The jetting mechanism does not require rotation of the bottom hole assembly or drill string, which is essential for use with Coiled Tubing (CT). It also has low reactive forces acting on the CT and generates cuttings small enough to be easily cleaned from the well bore, which is important in horizontal drilling. These cutting and mud processing components and capabilities compliment the concepts put forth by DOE for microhole coiled tubing drilling (MHTCTD) and should help insure the reality of drilling small diameter holes quickly and inexpensively with a minimal environmental footprint and that is efficient, compact and portable. Other components (site liners, sump and transfer pumps, stacked shakers, filter membranes, etc.. ) of the overall mud system were identified as readily available in industry and will not be purchased until we are ready to drill a specific well.

  12. Lexical frequency and voice assimilation.

    Science.gov (United States)

    Ernestus, Mirjam; Lahey, Mybeth; Verhees, Femke; Baayen, R Harald

    2006-08-01

    Acoustic duration and degree of vowel reduction are known to correlate with a word's frequency of occurrence. The present study broadens the research on the role of frequency in speech production to voice assimilation. The test case was regressive voice assimilation in Dutch. Clusters from a corpus of read speech were more often perceived as unassimilated in lower-frequency words and as either completely voiced (regressive assimilation) or, unexpectedly, as completely voiceless (progressive assimilation) in higher-frequency words. Frequency did not predict the voice classifications over and above important acoustic cues to voicing, suggesting that the frequency effects on the classifications were carried exclusively by the acoustic signal. The duration of the cluster and the period of glottal vibration during the cluster decreased while the duration of the release noises increased with frequency. This indicates that speakers reduce articulatory effort for higher-frequency words, with some acoustic cues signaling more voicing and others less voicing. A higher frequency leads not only to acoustic reduction but also to more assimilation.

  13. Four-stranded coiled-coil elastic protein in the byssus of the giant clam, Tridacna maxima.

    Science.gov (United States)

    Miserez, Ali; Li, Youli; Cagnon, Joel; Weaver, James C; Waite, J Herbert

    2012-02-13

    An elastic protein with a secondary structure distinct from all well-known load-bearing proteins is found in the byssus of the giant clam, Tridacna maxima . The byssus consists of a bundle of hundreds of individual threads, each measuring about about 100 μm in diameter, which exhibit a tendon-like mechanical response. The amino acid composition of Tridacna byssus, however, is unlike tendon collagen, lacking high glycine, proline, and hydroxyproline. Wide-angle X-ray scattering (WAXS) and small-angle X-ray scattering (SAXS) measurements suggest that the constituent nanofibrils of the byssal threads are distinct from known secondary structure motifs previously reported for elastic proteins including the collagen triple-helix, the β-sheet nanocrystalline domains of silks, or the double-stranded coiled-coil regions of intermediate filaments. Instead, X-ray diffraction data indicate a structural organization in which four coiled-coil α-helices form a stable rope-like structure, which then further pack in a pseudohexagonal lattice to form nanofibrils. Amino acid composition analysis shows unusually high concentrations of acidic as well as basic residues, suggesting that the four-helix structure is stabilized by strong ionic interactions between oppositely charged residues in neighboring strands. The composition also suggests additional stabilization by disulfide cross-linking. On a larger scale, scanning and conventional transmission electron microscope (STEM and TEM) observations indicate that the nanofibrils exhibit an alternating periodicity of about 500 nm along the axial direction. A molecular model that combines the mechanical properties with the structural characteristics of the Tridacna byssal threads is proposed.

  14. Diameters of Triton and Pluto

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, D.; Cruikshank, D.P. (Hawaii Univ., Honolulu (USA). Inst. for Astronomy); Brown, R.H. (Hawaii Univ., Honolulu (USA). Dept. of Physics and Astronomy; Hawaii Univ., Honolulu (USA). Hawaii Inst. of Geophysics)

    1982-12-02

    Upper limits are reported to the thermal IR emission from Triton, the major satellite of Neptune, and Pluto, the outermost planet, that permit significant upper limits to be set on their diameters and also demonstrate that both are high albedo objects. These results exclude the possibility that Triton is the largest planetary satellite and are consistent with the small size of Pluto deduced from other data.

  15. [The vocal rehabilitation with ESKA-Herrmann voice prosthesis. a report of a 10 years' experience].

    Science.gov (United States)

    Schuldt, T; Kramp, B; Dommerich, S

    2012-10-01

    ESKA-Herrmann voice prosthesis are available for almost 30 years and are used for the vocal rehabilitation of laryngectomees. Nevertheless there are no studies about this voice prosthesis. Especially because of the smaller external diameter of 5.5 mm differents to other voice prostheses may be expected.We analyzed the 10-year patient documentation in retrospect.67 patients (63 m/4f) got the ESKA-Herrmann voice prosthesis, which could be used with a mean lifetime of 131.4 days. The main reason of changing the prostheses were dislocation (34/119), loss by coughing (34/119) and the leakage around the prostheses. In total a good voice was documented in 83.9% of the prostheses.ESKA-Herrmann voice prostheses are an alternative to other prostheses. Because of the smaller external diameter the dislocation and loss of the prosthesis occur more often than other models. But it's the only model that allows a designated spontaneous closure of the trachea-esophageal fistula after prosthesis removal.

  16. Voice Habits and Behaviors: Voice Care Among Flamenco Singers.

    Science.gov (United States)

    Garzón García, Marina; Muñoz López, Juana; Y Mendoza Lara, Elvira

    2017-03-01

    The purpose of this study is to analyze the vocal behavior of flamenco singers, as compared with classical music singers, to establish a differential vocal profile of voice habits and behaviors in flamenco music. Bibliographic review was conducted, and the Singer's Vocal Habits Questionnaire, an experimental tool designed by the authors to gather data regarding hygiene behavior, drinking and smoking habits, type of practice, voice care, and symptomatology perceived in both the singing and the speaking voice, was administered. We interviewed 94 singers, divided into two groups: the flamenco experimental group (FEG, n = 48) and the classical control group (CCG, n = 46). Frequency analysis, a Likert scale, and discriminant and exploratory factor analysis were used to obtain a differential profile for each group. The FEG scored higher than the CCG in speaking voice symptomatology. The FEG scored significantly higher than the CCG in use of "inadequate vocal technique" when singing. Regarding voice habits, the FEG scored higher in "lack of practice and warm-up" and "environmental habits." A total of 92.6% of the subjects classified themselves correctly in each group. The Singer's Vocal Habits Questionnaire has proven effective in differentiating flamenco and classical singers. Flamenco singers are exposed to numerous vocal risk factors that make them more prone to vocal fatigue, mucosa dehydration, phonotrauma, and muscle stiffness than classical singers. Further research is needed in voice training in flamenco music, as a means to strengthen the voice and enable it to meet the requirements of this musical genre. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  17. 49 CFR 236.730 - Coil, receiver.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Coil, receiver. 236.730 Section 236.730 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Coil, receiver. Concentric layers of insulated wire wound around the core of a receiver of an...

  18. Operator coil monitoring Acceptance Test Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Erhart, M.F.

    1995-05-16

    The readiness of the Data Acquisition and Control System (DACS) to provide monitoring and control of the Programmable Logic Controller (PLC) abort coils from the Master and RSS stations will be systematically tested during performance of this procedure. It should be noted that these are not physical abort coils but software coils controlled by the software`s ladder logic. The readiness of the DACS to properly interface with the ENRAF wire level gauge installed in the SY-101 storage tank will also be tested. During this test, a verification of all abort coil indications will be conducted at the DACS Development Facility in the 306E Building by injecting an input signal for each DACS sensor that has an associated abort coil until the abort coil actuates, and then ensuring that the status of the abort coil indicated at the Master and RSS stations is correct. Each abort coil will also be tested to ensure that the ``ENABLE`` and ``DISABLE`` controls from the Master and RSS stations function correctly, and only with the use of proper passwords.

  19. Evidence-based pathology: umbilical cord coiling.

    Science.gov (United States)

    Khong, T Y

    2010-12-01

    The generation of a pathology test result must be based on criteria that are proven to be acceptably reproducible and clinically relevant to be evidence-based. This review de-constructs the umbilical cord coiling index to illustrate how it can stray from being evidence-based. Publications related to umbilical cord coiling were retrieved and analysed with regard to how the umbilical coiling index was calculated, abnormal coiling was defined and reference ranges were constructed. Errors and other influences that can occur with the measurement of the length of the umbilical cord or of the number of coils can compromise the generation of the coiling index. Definitions of abnormal coiling are not consistent in the literature. Reference ranges defining hypocoiling or hypercoiling have not taken those potential errors or the possible effect of gestational age into account. Even the way numerical test results in anatomical pathology are generated, as illustrated by the umbilical coiling index, warrants a critical analysis into its evidence base to ensure that they are reproducible or free from errors.

  20. Coil Optimization for High Temperature Superconductor Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    2011-01-01

    This paper presents topology optimization of HTS racetrack coils for large HTS synchronous machines. The topology optimization is used to acquire optimal coil designs for the excitation system of 3 T HTS machines. Several tapes are evaluated and the optimization results are discussed. The optimiz...

  1. Functional investigation of the plant-specific long coiled-coil proteins PAMP-INDUCED COILED-COIL (PICC and PICC-LIKE (PICL in Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Sowmya Venkatakrishnan

    Full Text Available We have identified and characterized two Arabidopsis long coiled-coil proteins PAMP-INDUCED COILED-COIL (PICC and PICC-LIKE (PICL. PICC (147 kDa and PICL (87 kDa are paralogs that consist predominantly of a long coiled-coil domain (expanded in PICC, with a predicted transmembrane domain at the immediate C-terminus. Orthologs of PICC and PICL were found exclusively in vascular plants. PICC and PICL GFP fusion proteins are anchored to the cytoplasmic surface of the endoplasmic reticulum (ER membrane by a C-terminal transmembrane domain and a short tail domain, via a tail-anchoring mechanism. T-DNA-insertion mutants of PICC and PICL as well as the double mutant show an increased sensitivity to the plant abiotic stress hormone abscisic acid (ABA in a post-germination growth response. PICC, but not PICL gene expression is induced by the bacterial pathogen-associated molecular pattern (PAMP flg22. T-DNA insertion alleles of PICC, but not PICL, show increased susceptibility to the non-virulent strain P. syringae pv. tomato DC3000 hrcC, but not to the virulent strain P. syringae pv. tomato DC3000. This suggests that PICC mutants are compromised in PAMP-triggered immunity (PTI. The data presented here provide first evidence for the involvement of a plant long coiled-coil protein in a plant defense response.

  2. Magnetic Fields at the Center of Coils

    Science.gov (United States)

    Binder, Philippe; Hui, Kaleonui; Goldman, Jesse

    2014-01-01

    In this note we synthesize and extend expressions for the magnetic field at the center of very short and very long current-carrying coils. Elementary physics textbooks present the following equation for the magnetic field inside a very long current-carrying coil (solenoid): B[subscript sol] = µ[subscript 0] (N/L) I, (1) where I is the current, N…

  3. Voices of the Unheard

    DEFF Research Database (Denmark)

    Matthiesen, Noomi Christine Linde

    2014-01-01

    . They were in two different classes at both schools, i.e. four classes in total. The families were followed for 18 months. Formal interviews were conducted with mothers and teachers, parent-teacher conferences were recorded, participant observations were conducted in classrooms and playgrounds, afterschool...... is that Somali diaspora parents (and with special focus on mothers as these where the parents who took most responsibility in the four cases of this research) have difficulty expressing their opinions as there are structural, historical and social dynamics that create conditions in which their voices...... are silenced, or at least restricted significantly, resulting in marginalizing consequences. The focus in each article is on here-and-now interactional dynamics but in order to understand these constitutive negotiations, it is argued that the analysis must be situated in a description of the constituted...

  4. Passing on power & voice

    DEFF Research Database (Denmark)

    Noer, Vibeke Røn; Nielsen, Cathrine Sand

    2014-01-01

    . The education lasts for 3,5 years and the landmark of the educational model is the continuously shifts between teaching in classroom and teaching in clinical practice. Clinical teaching takes place at approved clinical placement institutions in hospitals and in the social and health care services outside...... intention of gaining knowledge about other possible ways to perform the education. The class, named the E-class, followed what in the field was named ‘an experimental educational model based on experienced-based learning’ (Nielsen et al. 2011). The experiential educational model is argued as an experiment.......aspx Higher degree of student involvement in planning as well as teaching was in the field presented as a part of ‘the overall educational approach’. In the course ‘Acute, Critical Nursing & Terminal, Palliative Care’ this was transferred into an innovative pedagogy with intend to pass on power and voice...

  5. Voice stress analysis

    Science.gov (United States)

    Brenner, Malcolm; Shipp, Thomas

    1988-01-01

    In a study of the validity of eight candidate voice measures (fundamental frequency, amplitude, speech rate, frequency jitter, amplitude shimmer, Psychological Stress Evaluator scores, energy distribution, and the derived measure of the above measures) for determining psychological stress, 17 males age 21 to 35 were subjected to a tracking task on a microcomputer CRT while parameters of vocal production as well as heart rate were measured. Findings confirm those of earlier studies that increases in fundamental frequency, amplitude, and speech rate are found in speakers involved in extreme levels of stress. In addition, it was found that the same changes appear to occur in a regular fashion within a more subtle level of stress that may be characteristic, for example, of routine flying situations. None of the individual speech measures performed as robustly as did heart rate.

  6. Voice over IP

    OpenAIRE

    Mantula, Juha

    2006-01-01

    Tämä opinnäytetyö käsittelee Voice over Internet Protocol -tekniikkaa ja sen tuomia mahdollisuuksia yrityselämässä. Teoriaosa käsittelee VoIP:n kannalta tärkeitä pro-tokollia ja standardeja, VoIP:n ominaisuuksia sekä esittelee erilaisia puheohjelmia, jotka käyttävät VoIP-tekniikkaa hyväkseen. Empiirinen osuus tutkii Viestintä Ky Pitkärannan Skype-ohjelman käyttöä. Työn tarkoituksena on selvittää VoIP:n hyviä ja huonoja puolia ja sitä kuinka tek-niikkaa voidaan käyttää hyväksi päivittäisessä ...

  7. NMR local coil with adjustable spacing

    Energy Technology Data Exchange (ETDEWEB)

    Dembinski, G.T.

    1988-03-22

    A local coil assembly for use in NMR imaging is described which comprises: a base; a first local coil module mounted to the base and extending upward therefrom; sockets disposed in the base, each at a different distance from the first local coil module; a second local coil module having a connector therein which mates with each of the sockets to enable the second local coil module to be connected to the base at any one of the sockets; and a set of reactive components. The values of the respective reactive components are selected such that the second local oil module may be connected to any of the sockets without any substantial change in the resonant frequency of the assembly.

  8. A study on geometry effect of transmission coil for micro size magnetic induction coil

    Science.gov (United States)

    Lee, Kyung Hwa; Jun, Byoung Ok; Kim, Seunguk; Lee, Gwang Jun; Ryu, Mingyu; Choi, Ji-Woong; Jang, Jae Eun

    2016-05-01

    The effects of transmission (Tx) coil structure have been studied for micro-size magnetic induction coil. The size of the receiving (Rx) coil should be shrunk to the micrometer level for the various new applications such as micro-robot and wireless body implanted devices. In case of the macro-scale magnetic induction coil, the power transmission efficiency is generally considered to be higher as the inductance of the transmission coil became larger; however, the large size difference between macro-size Tx coil and micro-size Rx coil can decrease the power transmission efficiency due to the difference of resonance frequency. Here, we study a correlation of the power transmission with the size and distance between the macro-size Tx and micro-size Rx coils using magnetic induction technique. The maximum power efficiency was 0.28/0.23/0.13/0.12% at the distance of 0.3/1/3/5 cm between Rx and Tx coil. In addition, more efficient wireless power transferring method is suggested with a floating coil for the body implantable devices. The voltage output increased up to 5.4 mV than the original one Tx coil system. The results demonstrated the foundational wireless power transferring system with enhanced power efficiency.

  9. Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus.

    Science.gov (United States)

    Hillar, Alexander; Tripet, Brian; Zoetewey, David; Wood, Janet M; Hodges, Robert S; Boggs, Joan M

    2003-12-30

    Electron paramagnetic resonance spectroscopy was used to determine relative peptide orientation within homodimeric, alpha-helical coiled-coil structures. Introduction of cysteine (Cys) residues into peptides/proteins for spin labeling allows detection of their oligomerization from exchange broadening or dipolar interactions between residues within 25 A of each other. Two synthetic peptides containing Cys substitutions were used: a 35-residue model peptide and the 30-residue ProP peptide. The model peptide is known to form a stable, parallel homodimeric coiled coil, which is partially destabilized by Cys substitutions at heptad a and d positions (peptides C30a and C33d). The ProP peptide, a 30-residue synthetic peptide, corresponds to residues 468-497 of osmoregulatory transporter ProP from Escherichia coli. It forms a relatively unstable, homodimeric coiled coil that is predicted to be antiparallel in orientation. Cys was introduced in heptad g positions of the ProP peptide, near the N-terminus (K473C, creating peptide C473g) or closer to the center of the sequence (E480C, creating peptide C480g). In contrast to the destabilizing effect of Cys substitution at the core heptad a or d positions of model peptides C30a and C33d, circular dichroism spectroscopy showed that Cys substitutions at the heptad g positions of the ProP peptide had little or no effect on coiled-coil stability. Thermal denaturation analysis showed that spin labeling increased the stability of the coiled coil for all peptides. Strong exchange broadening was detected for both C30a and C33d, in agreement with a parallel structure. EPR spectra of C480g had a large hyperfine splitting of about 90 G, indicative of strong dipole-dipole interactions and a distance between spin-labeled residues of less than 9 A. Spin-spin interactions were much weaker for C473g. These results supported the hypothesis that the ProP peptide primarily formed an antiparallel coiled coil, since formation of a parallel dimer

  10. Voice and choice by delegation.

    Science.gov (United States)

    van de Bovenkamp, Hester; Vollaard, Hans; Trappenburg, Margo; Grit, Kor

    2013-02-01

    In many Western countries, options for citizens to influence public services are increased to improve the quality of services and democratize decision making. Possibilities to influence are often cast into Albert Hirschman's taxonomy of exit (choice), voice, and loyalty. In this article we identify delegation as an important addition to this framework. Delegation gives individuals the chance to practice exit/choice or voice without all the hard work that is usually involved in these options. Empirical research shows that not many people use their individual options of exit and voice, which could lead to inequality between users and nonusers. We identify delegation as a possible solution to this problem, using Dutch health care as a case study to explore this option. Notwithstanding various advantages, we show that voice and choice by delegation also entail problems of inequality and representativeness.

  11. The Christian voice in philosophy

    Directory of Open Access Journals (Sweden)

    Stuart Fowler

    1982-03-01

    Full Text Available In this paper the Rev. Stuart Fowler outlines a Christian voice in Philosophy and urges the Christian philosopher to investigate his position and his stance with integrity and honesty.

  12. Voice Force tulekul / Tõnu Ojala

    Index Scriptorium Estoniae

    Ojala, Tõnu, 1969-

    2005-01-01

    60. sünnipäeva tähistava Tallinna Tehnikaülikooli Akadeemilise Meeskoori juubelihooaja üritusest - a capella pop-gruppide festivalist Voice Force (kontserdid 12. nov. klubis Parlament ja 3. dets. Vene Kultuurikeskuses)

  13. Voice Force tulekul / Tõnu Ojala

    Index Scriptorium Estoniae

    Ojala, Tõnu, 1969-

    2005-01-01

    60. sünnipäeva tähistava Tallinna Tehnikaülikooli Akadeemilise Meeskoori juubelihooaja üritusest - a capella pop-gruppide festivalist Voice Force (kontserdid 12. nov. klubis Parlament ja 3. dets. Vene Kultuurikeskuses)

  14. Feature Extraction of Voice Segments Using Cepstral Analysis for Voice Regeneration

    OpenAIRE

    Banerjee, P. S.; Baisakhi Chakraborty; Jaya Banerjee

    2015-01-01

    Even though a lot of work has been done on areas of speech to text and vice versa or voice detection or similarity analysis of two voice samples but very less emphasis has be given to voice regeneration. General algorithms for distinct voice checking for two voice sources paved way for our endeavor in reconstructing the voice from the source voice samples provided. By utilizing these algorithms and putting further stress on the feature extraction part we tried to fabricate the source voice wi...

  15. Voice Simulation in Nursing Education.

    Science.gov (United States)

    Kepler, Britney B; Lee, Heeyoung; Kane, Irene; Mitchell, Ann M

    2016-01-01

    The goal of this study was to improve prelicensure nursing students' attitudes toward and self-efficacy related to delivering nursing care to patients with auditory hallucinations. Based on the Hearing Voices That Are Distressing curriculum, 87 participants were instructed to complete 3 tasks while wearing headphones delivering distressing voices. Comparing presimulation and postsimulation results, this study suggests that the simulation significantly improved attitudes toward patients with auditory hallucinations; however, self-efficacy related to caring for these patients remained largely unchanged.

  16. Work-related voice disorder

    OpenAIRE

    Paulo Eduardo Przysiezny; Luciana Tironi Sanson Przysiezny

    2015-01-01

    INTRODUCTION: Dysphonia is the main symptom of the disorders of oral communication. However, voice disorders also present with other symptoms such as difficulty in maintaining the voice (asthenia), vocal fatigue, variation in habitual vocal fundamental frequency, hoarseness, lack of vocal volume and projection, loss of vocal efficiency, and weakness when speaking. There are several proposals for the etiologic classification of dysphonia: functional, organofunctional, organic, and work-related...

  17. Tracheostomy cannulas and voice prosthesis.

    Science.gov (United States)

    Kramp, Burkhard; Dommerich, Steffen

    2009-01-01

    Cannulas and voice prostheses are mechanical aids for patients who had to undergo tracheotomy or laryngectomy for different reasons. For better understanding of the function of those artificial devices, first the indications and particularities of the previous surgical intervention are described in the context of this review. Despite the established procedure of percutaneous dilatation tracheotomy e.g. in intensive care units, the application of epithelised tracheostomas has its own position, especially when airway obstruction is persistent (e.g. caused by traumata, inflammations, or tumors) and a longer artificial ventilation or special care of the patient are required. In order to keep the airways open after tracheotomy, tracheostomy cannulas of different materials with different functions are available. For each patient the most appropriate type of cannula must be found. Voice prostheses are meanwhile the device of choice for rapid and efficient voice rehabilitation after laryngectomy. Individual sizes and materials allow adaptation of the voice prostheses to the individual anatomical situation of the patients. The combined application of voice prostheses with HME (Head and Moisture Exchanger) allows a good vocal as well as pulmonary rehabilitation. Precondition for efficient voice prosthesis is the observation of certain surgical principles during laryngectomy. The duration of the prosthesis mainly depends on material properties and biofilms, mostly consisting of funguses and bacteries. The quality of voice with valve prosthesis is clearly superior to esophagus prosthesis or electro-laryngeal voice. Whenever possible, tracheostoma valves for free-hand speech should be applied. Physicians taking care of patients with speech prostheses after laryngectomy should know exactly what to do in case the device fails or gets lost.

  18. Voice Collection under Different Spectrum

    Directory of Open Access Journals (Sweden)

    Min Li

    2013-05-01

    Full Text Available According to the short-time Fourier transform theory and principle of digital filtering, this paper established a mathematical model called collection of voice signal collection at different spectrum. The voice signal was a non-stationary process, while the standard Fourier transform only applied to the periodic signal, transient signals or stationary random signal. Therefore, the standard Fourier transform could not be directly used for the speech signal. By controlling the input different types and parameters, this paper analyzed the collected original voice signal spectrum with the use of MATLAB software platform. At the same time, it realized the extraction, recording and playback of the speech signal at different frequencies. Therefore, the waveforms could be displayed obviously on the graphic user interface and voice effect could be more clearly. Meanwhile, the result was verified by the hardware platforms, which consisted of TMS320VC5509A [1] chip and TLV320AIC23 voice chip. The results showed that the extraction of voice signal under different spectrum model was scientific, rational and effective.

  19. Endovascular Treatment of a Huge Hepatic Artery Aneurysm by Coil Embolization Method: A Case Report.

    Science.gov (United States)

    Hemmati, Hossein; Karimian, Mehdi; Moradi, Habibollah; Farid Marandi, Kambiz; Haghdoost, Afrooz

    2015-07-01

    Hepatic artery aneurysms are rare but potentially life threatening. We describe a novel case of a successful endovascular coil embolization of a huge hepatic artery aneurysm. A 67-year-old woman presented with recent abdominal pain that had begun from 2 weeks before referring to our hospital. Sonographic and computerized tomographic (CT) findings revealed a huge hepatic artery aneurysm with 95 mm × 83 mm diameter. The patient underwent an endovascular technique. In aortic angiography, the celiac artery orifice and superior mesenteric artery were so narrow, so sonography was used in order to determine the exact position of the catheter in the celiac artery orifice. The aneurysm was thrombosed using coil embolization. Pulsation of the aneurysm immediately disappeared. Huge hepatic artery aneurysm can be safely treated using coil embolization.

  20. Controlling the Self-Assembly of Semiconducting Nanocrystals within Conjugated Rod-Coil Block Copolymers

    Science.gov (United States)

    McCulloch, Bryan L.; Urban, Jeff J.; Segalman, Rachel A.

    2010-03-01

    Blends of conjugated polymers and inorganic nanoparticles have been investigated for numerous optoelectronic applications however optimization relies on precise control over the nanoscale morphologies. Here, we show that conjugated rod-coil block copolymers can be designed to self assemble into controllable morphologies with the coil block templating nanocrystal location. We have constructed a model system where nanocrystals are blended with poly(alkoxy-phenylene vinylene-b-2-vinylpyridine) (PPV-b-P2VP), which self assembles into tunable morphologies. Semiconducting nanocrystals reside within the P2VP domain, due to the favorable interactions between P2VP and the nanoparticle surface as well as the exclusionary effects of the liquid crystalline PPV. The placement of the nanoparticles can be tuned by altering domain size, nanocrystal diameter and nanocrystal surface chemistry. These findings are used to develop a comprehensive understanding of the self assembly processes in conjugated rod-coil block copolymer nanocomposites.

  1. Fast connection of large-diameter PE pipes. A new generation of heating coil welding technologies. A technical comparison between the new wedge-shaped joint and the conventional cylindrical foint for PE pipes d 1000 and larger; PE-Grossrohre im Handumdrehen verbinden. Eine neue Generation der Heizwendelschweisstechnik. Ein technischer Vergleich zwischen der neuen Keilmuffe und der herkoemmlichen zylindrischen Muffe fuer PE-Rohre d 1000 und groesser

    Energy Technology Data Exchange (ETDEWEB)

    Eckert, Robert [FRIATEC AG, Mannheim (Germany)

    2011-07-01

    Wedge-shape joints are a revolution in large-diameter pipe connection. Fitting is simplified considerably as compared to conventional cylindrical joints. Reproducible high-quality connections are achieved at only a fraction of the time formerly required. Assembly follows clear and simple rules. Anybody who can assemble a flange will be able to cope with the tightening system of the wedge-shaped joint.

  2. The impact of voice on speech realization

    Directory of Open Access Journals (Sweden)

    Jelka Breznik

    2014-12-01

    Full Text Available The study discusses spoken literary language and the impact of voice on speech realization. The voice consists of a sound made by a human being using the vocal folds for talking, singing, laughing, crying, screaming… The human voice is specifically the part of human sound production in which the vocal folds (vocal cords are the primary sound source. Our voice is our instrument and identity card. How does the voice (voice tone affect others and how do they respond, positively or negatively? How important is voice (voice tone in communication process? The study presents how certain individuals perceive voice. The results of the research on the relationships between the spoken word, excellent speaker, voice and description / definition / identification of specific voices done by experts in the field of speech and voice as well as non-professionals are presented. The study encompasses two focus groups. One consists of amateurs (non-specialists in the field of speech or voice who have no knowledge in this field and the other consists of professionals who work with speech or language or voice. The questions were intensified from general to specific, directly related to the topic. The purpose of such a method of questioning was to create relaxed atmosphere, promote discussion, allow participants to interact, complement, and to set up self-listening and additional comments.

  3. Simultaneous formation of right- and left-handed anti-parallel coiled-coil interfaces by a coil2 fragment of human lamin A.

    Science.gov (United States)

    Kapinos, Larisa E; Burkhard, Peter; Herrmann, Harald; Aebi, Ueli; Strelkov, Sergei V

    2011-04-22

    The elementary building block of all intermediate filaments (IFs) is a dimer featuring a central α-helical rod domain flanked by the N- and C-terminal end domains. In nuclear IF proteins (lamins), the rod domain consists of two coiled-coil segments, coil1 and coil2, that are connected by a short non-helical linker. Coil1 and the C-terminal part of coil2 contain the two highly conserved IF consensus motifs involved in the longitudinal assembly of dimers. The previously solved crystal structure of a lamin A fragment (residues 305-387) corresponding to the second half of coil2 has yielded a parallel left-handed coiled coil. Here, we present the crystal structure and solution properties of another human lamin A fragment (residues 328-398), which is largely overlapping with fragment 305-387 but harbors a short segment of the tail domain. Unexpectedly, no parallel coiled coil forms within the crystal. Instead, the α-helices are arranged such that two anti-parallel coiled-coil interfaces are formed. The most significant interface has a right-handed geometry, which is accounted for by a characteristic 15-residue repeat pattern that overlays with the canonical heptad repeat pattern. The second interface is a left-handed anti-parallel coiled coil based on the predicted heptad repeat pattern. In solution, the fragment reveals only a weak dimerization propensity. We speculate that the C-terminus of coil2 might unzip, thereby allowing for a right-handed coiled-coil interface to form between two laterally aligned dimers. Such an interface might co-exist with a heterotetrameric left-handed coiled-coil assembly, which is expected to be responsible for the longitudinal A(CN) contact.

  4. N@a and N@d: Oligomer and Partner Specification by Asparagine in Coiled-Coil Interfaces.

    Science.gov (United States)

    Fletcher, Jordan M; Bartlett, Gail J; Boyle, Aimee L; Danon, Jonathan J; Rush, Laura E; Lupas, Andrei N; Woolfson, Derek N

    2017-02-17

    The α-helical coiled coil is one of the best-studied protein-protein interaction motifs. As a result, sequence-to-structure relationships are available for the prediction of natural coiled-coil sequences and the de novo design of new ones. However, coiled coils adopt a wide range of oligomeric states and topologies, and our understanding of the specification of these and the discrimination between them remains incomplete. Gaps in our knowledge assume more importance as coiled coils are used increasingly to construct biomimetic systems of higher complexity; for this, coiled-coil components need to be robust, orthogonal, and transferable between contexts. Here, we explore how the polar side chain asparagine (Asn, N) is tolerated within otherwise hydrophobic helix-helix interfaces of coiled coils. The long-held view is that Asn placed at certain sites of the coiled-coil sequence repeat selects one oligomer state over others, which is rationalized by the ability of the side chain to make hydrogen bonds, or interactions with chelated ions within the coiled-coil interior of the favored state. We test this with experiments on de novo peptide sequences traditionally considered as directing parallel dimers and trimers, and more widely through bioinformatics analysis of natural coiled-coil sequences and structures. We find that when located centrally, rather than near the termini of such coiled-coil sequences, Asn does exert the anticipated oligomer-specifying influence. However, outside of these bounds, Asn is observed less frequently in the natural sequences, and the synthetic peptides are hyperthermostable and lose oligomer-state specificity. These findings highlight that not all regions of coiled-coil repeat sequences are equivalent, and that care is needed when designing coiled-coil interfaces.

  5. Spaced-based search coil magnetometers

    Science.gov (United States)

    Hospodarsky, George B.

    2016-12-01

    Search coil magnetometers are one of the primary tools used to study the magnetic component of low-frequency electromagnetic waves in space. Their relatively small size, mass, and power consumption, coupled with a good frequency range and sensitivity, make them ideal for spaceflight applications. The basic design of a search coil magnetometer consists of many thousands of turns of wire wound on a high permeability core. When a time-varying magnetic field passes through the coil, a time-varying voltage is induced due to Faraday's law of magnetic induction. The output of the coil is usually attached to a preamplifier, which amplifies the induced voltage and conditions the signal for transmission to the main electronics (usually a low-frequency radio receiver). Search coil magnetometers are usually used in conjunction with electric field antenna to measure electromagnetic plasma waves in the frequency range of a few hertz to a few tens of kilohertzs. Search coil magnetometers are used to determine the properties of waves, such as comparing the relative electric and magnetic field amplitudes of the waves, or to investigate wave propagation parameters, such as Poynting flux and wave normal vectors. On a spinning spacecraft, they are also sometimes used to determine the background magnetic field. This paper presents some of the basic design criteria of search coil magnetometers and discusses design characteristics of sensors flown on a number of spacecraft.

  6. Switching transients in a superconducting coil

    Energy Technology Data Exchange (ETDEWEB)

    Owen, E.W.; Shimer, D.W.

    1983-11-18

    A study is made of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to performance tests on the MFTF Yin-yang coils. It is found that the breaker opening time is the critical factor in determining the size and shape of the transient. Instantaneous opening of the breaker causes a lightly damped transient with large amplitude voltages to ground. Increasing the opening time causes the transient to become a monopulse of decreasing amplitude. The voltages at the external terminals are determined by the parameters of the external circuit. For fast opening times the frequency depends on the dump resistor inductance, the circuit capacitance, and the amplitude on the coil current. For slower openings the dump resistor inductance and the current determine the amplitude of the voltage to ground at the terminals. Voltages to ground are less in the interior of the coil, where transients related to the parameters of the coil itself are observed.

  7. Crystal structure of a coiled-coil domain from human ROCK I.

    Directory of Open Access Journals (Sweden)

    Daqi Tu

    Full Text Available The small GTPase Rho and one of its targets, Rho-associated kinase (ROCK, participate in a variety of actin-based cellular processes including smooth muscle contraction, cell migration, and stress fiber formation. The ROCK protein consists of an N-terminal kinase domain, a central coiled-coil domain containing a Rho binding site, and a C-terminal pleckstrin homology domain. Here we present the crystal structure of a large section of the central coiled-coil domain of human ROCK I (amino acids 535-700. The structure forms a parallel α-helical coiled-coil dimer that is structurally similar to tropomyosin, an actin filament binding protein. There is an unusual discontinuity in the coiled-coil; three charged residues (E613, R617 and D620 are positioned at what is normally the hydrophobic core of coiled-coil packing. We speculate that this conserved irregularity could function as a hinge that allows ROCK to adopt its autoinhibited conformation.

  8. Crystal Structure of the Central Coiled-Coil Domain from Human Liprin-[beta]2

    Energy Technology Data Exchange (ETDEWEB)

    Stafford, Ryan L.; Tang, Ming-Yun; Sawaya, Michael R.; Phillips, Martin L.; Bowie, James U. (UCLA)

    2012-02-07

    Liprins are a conserved family of scaffolding proteins important for the proper regulation and development of neuronal synapses. Humans have four liprin-{alpha}s and two liprin-{beta}s which all contain long coiled-coil domains followed by three tandem SAM domains. Complex interactions between the coiled-coil and SAM domains are thought to create liprin scaffolds, but the structural and biochemical properties of these domains remain largely uncharacterized. In this study we find that the human liprin-{beta}2 coiled-coil forms an extended dimer. Several protease-resistant subdomains within the liprin-{beta}1 and liprin-{beta}2 coiled-coils were also identified. A 2.0 {angstrom} crystal structure of the central, protease-resistant core of the liprin-{beta}2 coiled-coil reveals a parallel helix orientation. These studies represent an initial step toward determining the overall architecture of liprin scaffolds and understanding the molecular basis for their synaptic functions.

  9. Coil migration after endovascular coil occlusion of internal carotid artery pseudoaneurysms within the sphenoid sinus.

    Science.gov (United States)

    Struffert, T; Buhk, J H; Buchfelder, M; Rohde, V; Doerfler, A; Knauth, M

    2009-04-01

    We report two cases of coil migration after endovascular treatment of pseudoaneurysm of the internal carotid artery within the sphenoid sinus with coils and noncovered stents. Two patients underwent sphenoid sinus exposure for pituitary adenoma and chronic infection, respectively. As a complication pseudoaneurysms of the internal carotid artery within the sphenoid sinus developed. One patient was treated with stent and coils, the second with coils alone. Both patients experienced coil migration after 9 and 26 months, respectively, with the necessity for further treatment. Imaging was performed using flat detector computed tomography (FD-CT). Literature review revealed two additional cases of coil migration and four patients with the same treatment in stable condition. Pseudoaneurysms of the internal carotid artery are a special entity and the environment of the aneurysm within the sphenoid sinus may change over a long time. Coil embolization may lead to the late onset complication of coil migration with the possible risk of acute epistaxis. As a consequence, these patients need a careful and prolonged follow up. FD-CT is an appropriate technique to visualize the implanted coils and if present the migration of coil material.

  10. Effects of design parameters and puff topography on heating coil temperature and mainstream aerosols in electronic cigarettes

    Science.gov (United States)

    Zhao, Tongke; Shu, Shi; Guo, Qiuju; Zhu, Yifang

    2016-06-01

    Emissions from electronic cigarettes (ECs) may contribute to both indoor and outdoor air pollution and the number of users is increasing rapidly. ECs operate based on the evaporation of e-liquid by a high-temperature heating coil. Both puff topography and design parameters can affect this evaporation process. In this study, both mainstream aerosols and heating coil temperature were measured concurrently to study the effects of design parameters and puff topography. The heating coil temperatures and mainstream aerosols varied over a wide range across different brands and within same brand. The peak heating coil temperature and the count median diameter (CMD) of EC aerosols increased with a longer puff duration and a lower puff flow rate. The particle number concentration was positively associated with the puff duration and puff flow rate. These results provide a better understanding of how EC emissions are affected by design parameters and puff topography and emphasize the urgent need to better regulate EC products.

  11. Evaluation of persistent-mode operation in a superconducting MgB2 coil in solid nitrogen

    Science.gov (United States)

    Patel, Dipak; Hossain, Md Shahriar Al; See, Khay Wai; Qiu, Wenbin; Kobayashi, Hiroki; Ma, Zongqing; Kim, Seong Jun; Hong, Jonggi; Park, Jin Yong; Choi, Seyong; Maeda, Minoru; Shahabuddin, Mohammed; Rindfleisch, Matt; Tomsic, Mike; Xue Dou, Shi; Kim, Jung Ho

    2016-04-01

    We report the fabrication of a magnesium diboride (MgB2) coil and evaluate its persistent-mode operation in a system cooled by a cryocooler with solid nitrogen (SN2) as a cooling medium. The main purpose of SN2 was to increase enthalpy of the cold mass. For this work, an in situ processed carbon-doped MgB2 wire was used. The coil was wound on a stainless steel former in a single layer (22 turns), with an inner diameter of 109 mm and height of 20 mm without any insulation. The two ends of the coil were then joined to make a persistent-current switch to obtain the persistent-current mode. After a heat treatment, the whole coil was installed in the SN2 chamber. During operation, the resultant total circuit resistance was estimated to be magnetic resonance imaging application.

  12. Superconducting coil development and motor demonstration: Overview

    Science.gov (United States)

    Gubser, D. U.

    1995-12-01

    Superconducting bismuth-cuprate wires, coils, and magnets are being produced by industry as part of a program to test the viability of using such magnets in Naval systems. Tests of prototype magnets, coils, and wires reveal progress in commercially produced products. The larger magnets will be installed in an existing superconducting homopolar motor and operated initially at 4.2K to test the performance. It is anticipated that approximately 400 Hp will be achieved by the motor. This article reports on the initial tests of the magnets, coils, and wires as well as the development program to improve their performance.

  13. Magnetic field mapper based on rotating coils

    CERN Document Server

    AUTHOR|(CDS)2087244; Arpaia, Pasquale

    This thesis presents a magnetic field mapper based on rotating coils. The requirements, the architecture, the conceptual design, and the prototype for straight magnets were shown. The proposed system is made up of a rotating coil transducer and a train-like system for longitudinal motion and positioning inside magnet bore. The mapper allows a localized measurement of magnetic fields and the variation of the harmonic multipole content in the magnet ends. The proof-of-principle demonstration and the experimental characterization of the rotating-coil transducer specifically conceived for mapping validated the main objective of satisfying the magnetic measurement needs of the next generation of compact accelerators.

  14. The truth about laser fiber diameters.

    Science.gov (United States)

    Kronenberg, Peter; Traxer, Olivier

    2014-12-01

    To measure the various diameters of laser fibers from various manufacturers and compare them with the advertised diameter. Fourteen different unused laser fibers from 6 leading manufacturers with advertised diameters of 200, 270, 272, 273, 365, and 400 μm were measured by light microscopy. The outer diameter (including the fiber coating, cladding, and core), cladding diameter (including the cladding and the fiber core), and core diameter were measured. Industry representatives of the manufacturers were interviewed about the diameter of their fibers. For all fibers, the outer and cladding diameters differed significantly from the advertised diameter (P cladding, and core diameters of fibers with equivalent advertised diameters differed by up to 180, 100, and 78 μm, respectively. Some 200-μm fibers had larger outer diameters than the 270- to 273-μm fibers. All packaging material and all laser fibers lacked clear and precise fiber diameter information labels. Of 12 representatives interviewed, 8, 3, and 1 considered the advertised diameter to be the outer, the cladding, and the core diameter, respectively. Representatives within the same company frequently gave different answers. This study suggests that, at present, there is a lack of uniformity between laser fiber manufacturers, and most of the information conveyed to urologists regarding laser fiber diameter may be incorrect. Because fibers larger than the advertised laser fibers are known to influence key interventional parameters, this misinformation can have surgical repercussions. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Stent-assisted coiling of wide-necked intracranial aneurysms using the Solitaire AB stent

    Directory of Open Access Journals (Sweden)

    Vikram Huded

    2014-01-01

    Full Text Available Context: Stent-assisted coiling of wide-necked and complex intracranial aneurysms is an effective and feasible treatment option. The self-expanding, fully retrievable Solitaire AB (eV3, Irvine, CA, USA stent is the latest neurovascular remodeling device available. To the best of our knowledge, there are no studies of Solitaire AB-assisted coiling of wide-necked intracranial aneurysms from India. Aim: Solitaire AB-assisted coiling of wide-necked intracranial aneurysms. Materials and Methods: The study was conducted in a tertiary care center with a dedicated Interventional Neurology division from 2009 to 2013. Consecutive patients with wide-necked aneurysms who underwent coiling assisted by the Solitaire AB stent were enrolled in the study. Axium 3D and Helix (eV3, Irvine, CA, USA platinum coils were used to densely pack the aneurysm sac after deploying the stent across the neck. All patients were pretreated with antiplatelets according to protocol. Subsequently, dual antiplatelets were given for 6 months followed by continued aspirin. Outcome was assessed at 3 months using the modified Rankin Scale. Statistical Analysis Used: Statistical analysis was done using the SPSS 17.0 software. Results: A total of 16 patients underwent stent-assisted coiling. The most common site was the internal carotid artery (nine patients, median aneurysm size was 7 mm and median neck diameter was 5 mm. Thirteen patients presented with ruptured aneurysms. We achieved complete occlusion in all patients with no major complications. Thirteen patients were followed up, all have an mRS score of zero or one. Conclusion: We conclude that for wide-necked aneurysms, stent-assisted coiling using the Solitaire AB is a safe and effective treatment option.

  16. Development of a volume coil (PAAC) for 7T/400MMISS system (NIRS/ KOBELCO /Brucker)

    Energy Technology Data Exchange (ETDEWEB)

    Manabu, Nakajima; Iwao, Nakajima; Eiji, Yoshitome; Hiroo, Ikehira [National Institute of Radiological Sciences, Inage-ku, Chiba (Japan)

    2006-07-01

    We developed a new RF volume coil, P.A.A.C. (Path Antenna Array Coil), for monkey imaging by our 7 T MR System. We will report its structure and electrical characteristics. P.A.A.C. is configured by several Patch Antennas which were placed like an circular cylinder. Patch Antenna consists of it by plate like radiation device and ground board (a screen), and radiation device is covered by ground board. Each antenna was put on the parallel to the axis of the circular cylinder. This coil was designed to an antenna either for transmission and reception, experimentally. In transmission mode, the coil elements circularly polarized. We assumed the coil inside diameter 150 mm, it hold enough space to monkey' s head. As for Q, a very high value was obtained more than 450 at no loading at 300.3 MHz. Loaded by salt water, the Q value was 270. About 4 times signal-to-noise ratio signal was obtained with olive oil phantom i n this 7 Tesla system, compared to the 1.5 Tesla MR system. There are following characteristics to this coil. (1) Because the outside of ground board does not have most electric field, it i s easy to post a circuit attached to things such as an adjustment circuit and a blocking circuit in the inside of a coil. (2) We can choose feeding point at any place other than an element end an d can coordinate feeding point impedance hereby. We make use of such a good point and want to review more characteristic improvement. (author)

  17. Modelling of flexi-coil springs with rubber-metal pads in a locomotive running gear

    Directory of Open Access Journals (Sweden)

    Michálek T.

    2015-06-01

    Full Text Available Nowadays, flexi-coil springs are commonly used in the secondary suspension stage of railway vehicles. Lateral stiffness of these springs is influenced by means of their design parameters (number of coils, height, mean diameter of coils, wire diameter etc. and it is often suitable to modify this stiffness in such way, that the suspension shows various lateral stiffness in different directions (i.e., longitudinally vs. laterally in the vehicle-related coordinate system. Therefore, these springs are often supplemented with some kind of rubber-metal pads. This paper deals with modelling of the flexi-coil springs supplemented with tilting rubber-metal tilting pads applied in running gear of an electric locomotive as well as with consequences of application of that solution of the secondary suspension from the point of view of the vehicle running performance. This analysis is performed by means of multi-body simulations and the description of lateral stiffness characteristics of the springs is based on results of experimental measurements of these characteristics performed in heavy laboratories of the Jan Perner Transport Faculty of the University of Pardubice.

  18. Dryout occurrence in a helically coiled steam generator for nuclear power application

    Directory of Open Access Journals (Sweden)

    Santini L.

    2014-03-01

    Full Text Available Dryout phenomena have been experimentally investigated in a helically coiled steam generator tube. The experiences carried out in the present work are part of a wide experimental program devoted to the study of a GEN III+ innovative nuclear power plant [1].The experimental facility consists in an electrically heated AISI 316L stainless steel coiled tube. The tube is 32 meters long, 12.53 mm of inner diameter, with a coil diameter of 1m and a pitch of 0.79 m, resulting in a total height of the steam generator of 8 meters. The thermo-hydraulics conditions for dryout investigations covered a spectrum of mass fluxes between 199 and 810 kg/m2s, the pressures ranges from 10.7 to 60.7 bar, heat fluxes between 43.6 to 209.3 kW/m2.Very high first qualities dryout, between 0.72 and 0.92, were found in the range of explored conditions, comparison of our results with literature available correlations shows the difficulty in predicting high qualities dryout in helical coils., immediately following the heading. The text should be set to 1.15 line spacing. The abstract should be centred across the page, indented 15 mm from the left and right page margins and justified. It should not normally exceed 200 words.

  19. Measurement of steady and transient liquid coiling with high-speed video and digital image processing

    Science.gov (United States)

    Mier, Frank Austin; Bhakta, Raj; Castano, Nicolas; Thackrah, Joshua; Marquis, Tyler; Garcia, John; Hargather, Michael

    2016-11-01

    Liquid coiling occurs as a gravitationally-accelerated viscous fluid flows into a stagnant reservoir causing a localized accumulation of settling material, commonly designated as stack. This flow is broadly characterized by a vertical rope of liquid, the tail, flowing into the stack in a coiled motion with frequency defined parametrically within four different flow regimes. These regimes are defined as viscous, gravitational, inertial-gravitational, and inertial. Relations include parameters such as flow rate, drop height, rope radius, gravitational acceleration, and kinematic viscosity. While previous work on the subject includes high speed imaging, only basic and often averaged measurements have been taken by visual inspection of images. Through the implementation of additional image processing routines in MATLAB, time resolved measurements are taken on coiling frequency, tail diameter, stack diameter and height. Synchronization between a high speed camera and stepper motor driven syringe pump provides accurate correlation with flow rate. Additionally, continuous measurement of unsteady transition between flow regimes is visualized and quantified. This capability allows a deeper experimental understanding of processes involved in the liquid coiling phenomenon.

  20. Studies on the performance of different coiled column configurations for compact type-I countercurrent chromatography.

    Science.gov (United States)

    Yang, Yi; Gu, Dongyu; Aisa, Haji Akber; Ito, Yoichiro

    2011-05-01

    Three types of novel coiled column configurations, i.e. a triangular coiled column and elliptical coiled columns I and II, were designed for type-I countercurrent chromatography and their performances were evaluated with two solvent systems each with suitable test samples. Three dinitrophenyl (DNP) amino acids (DNP-DL-glu, DNP-β-ala and DNP-L-ala) were separated with a moderately hydrophobic two-phase solvent system composed of hexane-ethyl acetate-metanol-0.1 M hydrochloric acid (1:1:1:1, v/v), while two dipeptides (tryptophyl-tyrosine and valyl-tyrosine) were separated with a polar solvent system composed of 1-butanol-acetic acid-water (4.75:0.25:5, v/v). The overall results indicated that the performance of compact type-I countercurrent chromatography was improved by elliptical coiled column I which was mounted with its maximum coil diameter perpendicular to the surface of the column holder. Hydrodynamic effects involved in these separations were discussed. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. High-sensitivity cooled coil system for nuclear magnetic resonance in kHz range.

    Science.gov (United States)

    Lin, Tingting; Zhang, Yi; Lee, Yong-Ho; Krause, Hans-Joachim; Lin, Jun; Zhao, Jing

    2014-11-01

    In several low-field Nuclear Magnetic Resonance (LF-NMR) and surface nuclear magnetic resonance applications, i.e., in the frequency range of kHz, high sensitivity magnetic field detectors are needed. Usually, low-Tc superconducting quantum interference devices (SQUIDs) with a high field sensitivity of about 1 fT/Hz(1/2) are employed as detectors. Considering the flux trapping and operational difficulties associated with low-Tc SQUIDs, we designed and fabricated liquid-nitrogen-cooled Cu coils for NMR detection in the kHz range. A cooled coil system consisting of a 9-cm diameter Cu coil and a low noise preamplifier was systematically investigated and reached a sensitivity of 2 fT/Hz(1/2) at 77 K, which is 3 times better compared to the sensitivity at 300 K. A Q-switch circuit as an essential element for damping the ringing effects of the pickup coil was developed to acquire free induction decay signals of a water sample with minimum loss of signal. Our studies demonstrate that cooled Cu coils, if designed properly, can provide a comparable sensitivity to low-Tc SQUIDs.

  2. Completion of designing and manufacturing of the coil support structure of W7-X

    Energy Technology Data Exchange (ETDEWEB)

    Chauvin, Didier, E-mail: didier.chauvin@ipp.mpg.de [Max-Planck-Institut fuer Plasmaphysik, Teilinstitut Greifswald, Wendelsteinstr. 1, D-17491 Greifswald (Germany); Koppe, Torsten; Cardella, Antonio; Missal, Bernd; Pilopp, Dirk [Max-Planck-Institut fuer Plasmaphysik, Teilinstitut Greifswald, Wendelsteinstr. 1, D-17491 Greifswald (Germany); Di Bartolo, Giovanni [M and G srl Consultants, Via Dei Romanelli 8, I-20034 Giussano (Italy); Camin, Rocio; Gonzales, Ivan [Equipos Nucleares S.A., Avda. Juan Carlos 1, 39600 Maliano (Spain); Giordano, Luca [ROVERA Costruzioni Meccaniche, Via Vecchia di Cuneo 45, 12011 Borgo san Dalmazzo (Italy); Langone, Stefano [Romabau Gerinox AG, Fohlenweide, CH-8570 Weinfelden/Thurgau (Switzerland)

    2011-10-15

    In February 2000, the project called coil support structure for the Wendelstein 7-X fusion machine was started. Since October 2009 the full production of this big (80 tons) and complex component is now completed and delivered at IPP Greifswald. The W7-X coil system consists of 20 planar and 50 non-planar coils. They are supported by a pentagonal 10 m diameter, 2.5 m high called coil support structure (CSS). The CSS is divided into five modules and each module consists of two equal half modules around the radial axis. Currently, the five modules were successfully assembled with the coils meeting the tight manufacturing tolerances. Designing, structural calculation, raw material procurement, welding and soldering technologies, milling, drilling, accurate machining, helium cooling pipe forming, laser metrology, ultra sonic cleaning and vacuum test are some of the key points used all along this successful manufacturing process. The lessons learned in the large scale production of this difficult kind of support structure will be presented as relevant experience for the realization of similar systems for future fusion devices, such as ITER.

  3. Mechanics of human voice production and control

    Science.gov (United States)

    Zhang, Zhaoyan

    2016-01-01

    As the primary means of communication, voice plays an important role in daily life. Voice also conveys personal information such as social status, personal traits, and the emotional state of the speaker. Mechanically, voice production involves complex fluid-structure interaction within the glottis and its control by laryngeal muscle activation. An important goal of voice research is to establish a causal theory linking voice physiology and biomechanics to how speakers use and control voice to communicate meaning and personal information. Establishing such a causal theory has important implications for clinical voice management, voice training, and many speech technology applications. This paper provides a review of voice physiology and biomechanics, the physics of vocal fold vibration and sound production, and laryngeal muscular control of the fundamental frequency of voice, vocal intensity, and voice quality. Current efforts to develop mechanical and computational models of voice production are also critically reviewed. Finally, issues and future challenges in developing a causal theory of voice production and perception are discussed. PMID:27794319

  4. Effect of the on/off Cycling Modulation Time Ratio of C2H2/SF6 Flows on the Formation of Geometrically Controlled Carbon Coils

    Directory of Open Access Journals (Sweden)

    Young-Chul Jeon

    2012-01-01

    Full Text Available Carbon coils could be synthesized using C2H2/H2 as source gases and SF6 as an incorporated additive gas under thermal chemical vapor deposition system. Nickel catalyst layer deposition and then hydrogen plasma pretreatment were performed prior to the carbon coils deposition reaction. To obtain the geometrically controlled carbon coils, the cycling on/off modulation process for C2H2/SF6 flows was introduced during the initial reaction. According to the different reaction processes, the different cycling on/off ratio and the different cycling numbers for C2H2/SF6 flows were carried out. The characteristics (formation density, morphology, and geometry of the deposited carbon coils on the substrate were investigated. Microsized coils as well as nanosized coils could be existed under the higher growing/etching time ratio (180/30 s condition. On the other hand, the formation of nanosized coils could be mainly observed under the lower growing/etching time ratio (30/180 s condition. With increasing the numbers of cycles, the diameters of carbon nanofilaments composed the coils decreased. The enhanced etching ability by the fluorine species was considered the main cause to control the geometry of carbon coils according to the growing/etching time ratio of the cycling on/off modulation process for C2H2/SF6 flows.

  5. Helical coil thermal hydraulic model

    Science.gov (United States)

    Caramello, M.; Bertani, C.; De Salve, M.; Panella, B.

    2014-11-01

    A model has been developed in Matlab environment for the thermal hydraulic analysis of helical coil and shell steam generators. The model considers the internal flow inside one helix and its associated control volume of water on the external side, both characterized by their inlet thermodynamic conditions and the characteristic geometry data. The model evaluates the behaviour of the thermal-hydraulic parameters of the two fluids, such as temperature, pressure, heat transfer coefficients, flow quality, void fraction and heat flux. The evaluation of the heat transfer coefficients as well as the pressure drops has been performed by means of the most validated literature correlations. The model has been applied to one of the steam generators of the IRIS modular reactor and a comparison has been performed with the RELAP5/Mod.3.3 code applied to an inclined straight pipe that has the same length and the same elevation change between inlet and outlet of the real helix. The predictions of the developed model and RELAP5/Mod.3.3 code are in fairly good agreement before the dryout region, while the dryout front inside the helical pipes is predicted at a lower distance from inlet by the model.

  6. Coil measurement data acquisition and curing press control system for SSC dipole magnet coils

    Energy Technology Data Exchange (ETDEWEB)

    Dickey, C.E.

    1989-03-01

    A coil matching program, similar in theory to the methods used to match Tevatron coils, is being developed at Fermilab. Modulus of elasticity and absolute coil size will be determined at 18-inch intervals along the coils while in the coil curing press immediately following the curing process. A data acquisition system is under construction to automatically acquire and manage the large quantities of data that result. Data files will be transferred to Fermilab's VAX Cluster for long-term storage and actual coil matching. The data acquisition system will also provide the control algorithm for the curing press hydraulic system. A description of the SSC Curing Press Data Acquisition and Controls System will be reported. 20 figs.

  7. Coil geometry effects on scanning single-coil magnetic induction tomography

    Science.gov (United States)

    Feldkamp, Joe R.; Quirk, Stephen

    2017-09-01

    Alternative coil designs for single coil magnetic induction tomography are considered in this work, with the intention of improving upon the standard design used previously. In particular, we note that the blind spot associated with this coil type, a portion of space along its axis where eddy current generation can be very weak, has an important effect on performance. The seven designs tested here vary considerably in the size of their blind spot. To provide the most discerning test possible, we use laboratory phantoms containing feature dimensions similar to blind spot size. Furthermore, conductivity contrasts are set higher than what would occur naturally in biological systems, which has the effect of weakening eddy current generation at coil locations that straddle the border between high and low conductivity features. Image reconstruction results for the various coils show that coils with smaller blind spots give markedly better performance, though improvements in signal-to-noise ratio could alter that conclusion.

  8. Magnetic propulsion of a magnetic device using three square-Helmholtz coils and a square-Maxwell coil.

    Science.gov (United States)

    Ha, Yong H; Han, Byung H; Lee, Soo Y

    2010-02-01

    We introduce a square coil system for remote magnetic navigation of a magnetic device without any physical movements of the coils. We used three square-Helmholtz coils and a square-Maxwell coil for magnetic propulsion of a small magnet along the desired path. All the square coils are mountable on a cubic frame that has an opening to accommodate a living subject. The square-Helmholtz coils control the magnetic propulsion direction by generating uniform magnetic field along the desired direction while the square-Maxwell coil controls the propulsion force by generating magnetic gradient field. We performed magnetic propulsion experiments with a down-scaled coil set and a three-channel coil driver. Experimental results demonstrate that we can use the square coil set for magnetic navigation of a magnetic device without any physical movements of the coils.

  9. Native voice, self-concept and the moral case for personalized voice technology.

    Science.gov (United States)

    Nathanson, Esther

    2017-01-01

    Purpose (1) To explore the role of native voice and effects of voice loss on self-concept and identity, and survey the state of assistive voice technology; (2) to establish the moral case for developing personalized voice technology. Methods This narrative review examines published literature on the human significance of voice, the impact of voice loss on self-concept and identity, and the strengths and limitations of current voice technology. Based on the impact of voice loss on self and identity, and voice technology limitations, the moral case for personalized voice technology is developed. Results Given the richness of information conveyed by voice, loss of voice constrains expression of the self, but the full impact is poorly understood. Augmentative and alternative communication (AAC) devices facilitate communication but, despite advances in this field, voice output cannot yet express the unique nuances of individual voice. The ethical principles of autonomy, beneficence and equality of opportunity establish the moral responsibility to invest in accessible, cost-effective, personalized voice technology. Conclusions Although further research is needed to elucidate the full effects of voice loss on self-concept, identity and social functioning, current understanding of the profoundly negative impact of voice loss establishes the moral case for developing personalized voice technology. Implications for Rehabilitation Rehabilitation of voice-disordered patients should facilitate self-expression, interpersonal connectedness and social/occupational participation. Proactive questioning about the psychological and social experiences of patients with voice loss is a valuable entry point for rehabilitation planning. Personalized voice technology would enhance sense of self, communicative participation and autonomy and promote shared healthcare decision-making. Further research is needed to identify the best strategies to preserve and strengthen identity and sense of

  10. Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain.

    Science.gov (United States)

    Barfoot, Tasida; Herdendorf, Timothy J; Behning, Bryanna R; Stohr, Bradley A; Gao, Yang; Kreuzer, Kenneth N; Nelson, Scott W

    2015-09-25

    Rad50 and Mre11 form a complex involved in the detection and processing of DNA double strand breaks. Rad50 contains an anti-parallel coiled-coil with two absolutely conserved cysteine residues at its apex. These cysteine residues serve as a dimerization domain and bind a Zn(2+) cation in a tetrathiolate coordination complex known as the zinc-hook. Mutation of the zinc-hook in bacteriophage T4 is lethal, indicating the ability to bind Zn(2+) is critical for the functioning of the MR complex. In vitro, we found that complex formation between Rad50 and a peptide corresponding to the C-terminal domain of Mre11 enhances the ATPase activity of Rad50, supporting the hypothesis that the coiled-coil is a major conduit for communication between Mre11 and Rad50. We constructed mutations to perturb this domain in the bacteriophage T4 Rad50 homolog. Deletion of the Rad50 coiled-coil and zinc-hook eliminates Mre11 binding and ATPase activation but does not affect its basal activity. Mutation of the zinc-hook or disruption of the coiled-coil does not affect Mre11 or DNA binding, but their activation of Rad50 ATPase activity is abolished. Although these mutants excise a single nucleotide at a normal rate, they lack processivity and have reduced repetitive exonuclease rates. Restricting the mobility of the coiled-coil eliminates ATPase activation and repetitive exonuclease activity, but the ability to support single nucleotide excision is retained. These results suggest that the coiled-coiled domain adopts at least two conformations throughout the ATPase/nuclease cycle, with one conformation supporting enhanced ATPase activity and processivity and the other supporting nucleotide excision.

  11. A Calibrating Device for Rogowski Coil Development

    Institute of Scientific and Technical Information of China (English)

    LV Liang; LI Junhao; HUANG Jianjun; JI Shengchang; LI Yanming

    2007-01-01

    A calibrating device for the Rogowski coil is developed,which can be used to calibrate the Rogowski coil having a partial response time within tens of nanoseconds.Its key component is a step current generator,which can generate the output with a rise time of less than 2 ns and a duration of larger than 300 ns.The step current generator is composed by a pulse forming line(PFL)and a pulse transmission line(PTL).A TEM(transverse electromagnetic mode)coaxial measurement unit is used as PTL,and the coil to be calibrated and the referenced standard Rogowski coil can be fixed in the unit.The effect of the dimensions of the TEM unit is discussed theoretically as well as experimentally.

  12. Screen-printed flexible MRI receive coils.

    Science.gov (United States)

    Corea, Joseph R; Flynn, Anita M; Lechêne, Balthazar; Scott, Greig; Reed, Galen D; Shin, Peter J; Lustig, Michael; Arias, Ana C

    2016-03-10

    Magnetic resonance imaging is an inherently signal-to-noise-starved technique that limits the spatial resolution, diagnostic image quality and results in typically long acquisition times that are prone to motion artefacts. This limitation is exacerbated when receive coils have poor fit due to lack of flexibility or need for padding for patient comfort. Here, we report a new approach that uses printing for fabricating receive coils. Our approach enables highly flexible, extremely lightweight conforming devices. We show that these devices exhibit similar to higher signal-to-noise ratio than conventional ones, in clinical scenarios when coils could be displaced more than 18 mm away from the body. In addition, we provide detailed material properties and components performance analysis. Prototype arrays are incorporated within infant blankets for in vivo studies. This work presents the first fully functional, printed coils for 1.5- and 3-T clinical scanners.

  13. Coiling Temperature Control in Hot Strip Mill

    Science.gov (United States)

    Imanari, Hiroyuki; Fujiyama, Hiroaki

    Coiling temperature is one of the most significant factors in products of hot strip mill to determine material properties such as strength, toughness of steel, so it is very important to achieve accurate coiling temperature control (CTC). Usually there are a few pyrometers on the run out table in hot strip mill, therefore temperature model and its adapting system have large influences on the accuracy of CTC. Also unscheduled change of rolling speed has a bad effect to keep coiling temperature as its target. Newly developed CTC system is able to get very accurate coiling temperature against uncertain factors and disturbances by adopting easily identified temperature model, learning method and dynamic set up function. The features of the CTC system are discussed with actual data, and the effectiveness of the system is shown by actual control results.

  14. MR angiography after coiling of intracranial aneurysms

    NARCIS (Netherlands)

    Schaafsma, J.D.

    2012-01-01

    Introduction Endovascular occlusion with detachable coils has become an alternative treatment to neurosurgical clipping of intracranial aneurysms over the last two decades. Its minimal invasiveness is the most important advantage of this treatment compared to clipping. The disadvantage of occlusion

  15. Mechanical resonances of helically coiled carbon nanowires

    National Research Council Canada - National Science Library

    Saini, D; Behlow, H; Podila, R; Dickel, D; Pillai, B; Skove, M J; Serkiz, S M; Rao, A M

    2014-01-01

    ...) mainly due to their geometrical complexity. The advent of helically coiled micro/nanoscale structures in nano-robotics, nano-inductors, and impact protection coatings has necessitated the development of new methodologies for determining...

  16. The Magnetic Field of Helmholtz Coils

    Science.gov (United States)

    Berridge, H. J. J.

    1975-01-01

    Describes the magnetic field of Helmholtz coils qualitatively and then provides the basis for a quantitative expression. Since the mathematical calculations are very involved, a computer program for solving the mathematical expression is presented and explained. (GS)

  17. Children's Voice or Children's Voices? How Educational Research Can Be at the Heart of Schooling

    Science.gov (United States)

    Stern, Julian

    2015-01-01

    There are problems with considering children and young people in schools as quite separate individuals, and with considering them as members of a single collectivity. The tension is represented in the use of "voice" and "voices" in educational debates. Voices in dialogue, in contrast to "children's voice", are…

  18. Voice complaints, risk factors for voice problems and history of voice problems in relation to puberty in female student teachers.

    NARCIS (Netherlands)

    Thomas, G.; Jong, F.I.C.R.S. de; Kooijman, P.G.C.; Donders, A.R.T.; Cremers, C.W.R.J.

    2006-01-01

    The aim of the study was to estimate voice complaints, risk factors for voice complaints and history of voice problems in student teachers before they embarked on their professional teaching career. A cross-sectional questionnaire survey was performed among female student teachers. The response rate

  19. Voice complaints, risk factors for voice problems and history of voice problems in relation to puberty in female student teachers.

    NARCIS (Netherlands)

    Thomas, G.; Jong, F.I.C.R.S. de; Kooijman, P.G.C.; Donders, A.R.T.; Cremers, C.W.R.J.

    2006-01-01

    The aim of the study was to estimate voice complaints, risk factors for voice complaints and history of voice problems in student teachers before they embarked on their professional teaching career. A cross-sectional questionnaire survey was performed among female student teachers. The response rate

  20. Human voice recognition depends on language ability.

    Science.gov (United States)

    Perrachione, Tyler K; Del Tufo, Stephanie N; Gabrieli, John D E

    2011-07-29

    The ability to recognize people by their voice is an important social behavior. Individuals differ in how they pronounce words, and listeners may take advantage of language-specific knowledge of speech phonology to facilitate recognizing voices. Impaired phonological processing is characteristic of dyslexia and thought to be a basis for difficulty in learning to read. We tested voice-recognition abilities of dyslexic and control listeners for voices speaking listeners' native language or an unfamiliar language. Individuals with dyslexia exhibited impaired voice-recognition abilities compared with controls only for voices speaking their native language. These results demonstrate the importance of linguistic representations for voice recognition. Humans appear to identify voices by making comparisons between talkers' pronunciations of words and listeners' stored abstract representations of the sounds in those words.

  1. Quick Statistics about Voice, Speech, and Language

    Science.gov (United States)

    ... here Home » Health Info » Statistics and Epidemiology Quick Statistics About Voice, Speech, Language Voice, Speech, Language, and ... no 205. Hyattsville, MD: National Center for Health Statistics. 2015. Hoffman HJ, Li C-M, Losonczy K, ...

  2. Introduction: Textual and contextual voices of translation

    DEFF Research Database (Denmark)

    2017-01-01

    Voices – marks of the tangle of subjectivities involved in textual processes – constitute the very fabric of texts in general and translations in particular. The title of this book, Textual and Contextual Voices of Translation, refers both to textual voices, that is, the voices found within...... the translated texts, and to contextual voices, that is, the voices of those involved in shaping, commenting, or otherwise influencing the textual voices. The latter appear in prefaces, reviews, and other texts that surround the translated texts and provide them with a context. Our main claim is that studying...... both the textual and contextual voices helps us better understand and explain the complexity of both the translation process and the translation product. The dovetailed approach to translation research that is advocated in this book aims at highlighting the diversity of participants, power positions...

  3. Constraint Cooling of Hot Rolled Coil

    Institute of Scientific and Technical Information of China (English)

    WANG Li-juan; ZHANG Chun-li

    2004-01-01

    The layer thermal conductivity during constraint cooling of hot rolled coil was described by using equivalent thermal conductivity model and finite element method. Two radial stress concentration zones in constraint cooled coil were shown by numerical analysis, and the tension stress was assumed to be the main factor to induce stress corrosion. The experimental results show that the longer the water cooling time is, the smaller the grain size and the more uniform the grains are.

  4. NUMERICAL INVESTIGATION FOR THE HEAT TRANSFER ENHANCEMENT IN HELICAL CONE COILS OVER ORDINARY HELICAL COILS

    Directory of Open Access Journals (Sweden)

    M. M. ABO ELAZM

    2013-02-01

    Full Text Available This numerical research is introducing the concept of helical cone coils and their enhanced heat transfer characteristics compared to the ordinary helical coils. Helical and spiral coils are known to have better heat and mass transfer than straight tubes, which is attributed to the generation of a vortex at the helical coil known as Dean Vortex. The Dean number which is a dimensionless number used to describe the Dean vortex is a function of Reynolds number and the square root of the curvature ratio, so varying the curvature ratio for the same coil would vary the Dean number. Two scenarios were adopted to study the effect of changing the taper angle (curvature ratio on the heat transfer characteristics of the coil; the commercial software FLUENT was used in the investigation. It was found that Nusselt number increased with increasing the taper angle. A MATLAB code was built based on empirical correlation of Manlapaz and Churchill for ordinary helical coils to calculate the Nusselt number at each coil turn, and then calculate the average Nusselt number for the entire coil turns, the CFD simulation results were found acceptable when compared with the MATLAB results.

  5. AC loss measurements in HTS coil assemblies with hybrid coil structures

    Science.gov (United States)

    Jiang, Zhenan; Long, Nicholas J.; Staines, Mike; Badcock, Rodney A.; Bumby, Chris W.; Buckley, Robert G.; Amemiya, Naoyuki

    2016-09-01

    Both AC loss and wire cost in coil windings are critical factors for high temperature superconductor (HTS) AC machinery applications. We present AC loss measurement results in three HTS coil assemblies at 77 K and 65 K which have a hybrid coil structure comprising one central winding (CW) and two end windings (EWs) wound with ReBCO and BSCCO wires with different self-field I c values at 77 K. All AC loss results in the coil assemblies are hysteretic and the normalized AC losses in the coil assemblies at different temperatures can be scaled with the I c value of the coil assemblies. The normalised results show that AC loss in a coil assembly with BSCCO CW can be reduced by using EWs wound with high I c ReBCO wires, whilst further AC loss reduction can be achieved by replacing the BSCCO CW with ReBCO CW. The results imply that a flexible hybrid coil structure is possible which considers both AC loss and wire cost in coil assemblies.

  6. A Condition for a Translation Quiver to Be a Coil

    Institute of Scientific and Technical Information of China (English)

    Bin ZHU; Zong Yi HU

    2003-01-01

    We single out a class of translation quivers and prove combinatorially that the translationquivers in this class are coils. These coils form a class of special coils. They are easier to visualize, butstill show all the strange behaviour of general coils, and contain quasi-stable tubes as special examples.

  7. Single-mode operation of a coiled multimode fiber amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey P. Koplow; Dahv A. V. Kliner; Lew Goldberg

    2000-01-19

    The authors report a new approach to obtain single-transverse-mode operation of a multimode fiber amplifier, in which the gain fiber is coiled to induce significant bend loss for all but the lowest-order mode. They have demonstrated this method by constructing a coiled amplifier using Yb-doped, double-clad fiber with a core diameter of 25 {micro}m and NA of {minus}0.1 (V {approx} 7.4). When operated as an ASE source, the output beam had an M{sup 2} value of 1.09 {+-} 0.09; when seeded at 1,064 nm, the slope efficiency was similar to that of an uncoiled amplifier. This technique does not require exotic fiber designs or increase system complexity and is inexpensive to implement. It will allow scaling of pulsed fiber lasers and amplifiers to significantly higher pulse energies and peak powers and cw fiber sources to higher average powers while maintaining excellent beam quality.

  8. A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3.

    Science.gov (United States)

    Simpson, Raina J Y; Yi Lee, Stella Hoi; Bartle, Natalie; Sum, Eleanor Y; Visvader, Jane E; Matthews, Jacqueline M; Mackay, Joel P; Crossley, Merlin

    2004-09-17

    Classic zinc finger domains (cZFs) consist of a beta-hairpin followed by an alpha-helix. They are among the most abundant of all protein domains and are often found in tandem arrays in DNA-binding proteins, with each finger contributing an alpha-helix to effect sequence-specific DNA recognition. Lone cZFs, not found in tandem arrays, have been postulated to function in protein interactions. We have studied the transcriptional co-regulator Friend of GATA (FOG), which contains nine zinc fingers. We have discovered that the third cZF of FOG contacts a coiled-coil domain in the centrosomal protein transforming acidic coiled-coil 3 (TACC3). Although FOG-ZF3 exhibited low solubility, we have used a combination of mutational mapping and protein engineering to generate a derivative that was suitable for in vitro and structural analysis. We report that the alpha-helix of FOG-ZF3 recognizes a C-terminal portion of the TACC3 coiled-coil. Remarkably, the alpha-helical surface utilized by FOG-ZF3 is the same surface responsible for the well established sequence-specific DNA-binding properties of many other cZFs. Our data demonstrate the versatility of cZFs and have implications for the analysis of many as yet uncharacterized cZF proteins.

  9. Speaker's voice as a memory cue.

    Science.gov (United States)

    Campeanu, Sandra; Craik, Fergus I M; Alain, Claude

    2015-02-01

    Speaker's voice occupies a central role as the cornerstone of auditory social interaction. Here, we review the evidence suggesting that speaker's voice constitutes an integral context cue in auditory memory. Investigation into the nature of voice representation as a memory cue is essential to understanding auditory memory and the neural correlates which underlie it. Evidence from behavioral and electrophysiological studies suggest that while specific voice reinstatement (i.e., same speaker) often appears to facilitate word memory even without attention to voice at study, the presence of a partial benefit of similar voices between study and test is less clear. In terms of explicit memory experiments utilizing unfamiliar voices, encoding methods appear to play a pivotal role. Voice congruency effects have been found when voice is specifically attended at study (i.e., when relatively shallow, perceptual encoding takes place). These behavioral findings coincide with neural indices of memory performance such as the parietal old/new recollection effect and the late right frontal effect. The former distinguishes between correctly identified old words and correctly identified new words, and reflects voice congruency only when voice is attended at study. Characterization of the latter likely depends upon voice memory, rather than word memory. There is also evidence to suggest that voice effects can be found in implicit memory paradigms. However, the presence of voice effects appears to depend greatly on the task employed. Using a word identification task, perceptual similarity between study and test conditions is, like for explicit memory tests, crucial. In addition, the type of noise employed appears to have a differential effect. While voice effects have been observed when white noise is used at both study and test, using multi-talker babble does not confer the same results. In terms of neuroimaging research modulations, characterization of an implicit memory effect

  10. Minimum Inductance Optimal Design for the Gradient Coil

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In MRI (Magnetic Resonance Imaging), a crucial role of gradient coils is to image organism, meanwhile the inductance of the coils determines the speed of imaging. So it is of great importance to optimize designs of the gradient coils. The target field approach is an effective method to design the gradient coils. Having applied this method and performing many numerical tests, we achieved the designs of the x-、y-、z- gradient coils , with the linearity of the fields generated by the coils in a sphere of radius 0.30 m less than 5%, in which the inductance and resistance of the coils also meet the requirements.

  11. Transport of one SC coil through the village of Meyrin

    CERN Multimedia

    1956-01-01

    In 1952, before CERN was officially founded, two accelerator projects were launched: one for an innovative accelerator to operate at an energy level unequalled at the time, the other for a more standard machine, a Synchro-Cyclotron (SC) to operate at 600 MeV. Design work on the SC was started in 1952 and carried out by teams scattered throughout Europe. Once construction began in 1954, CERN had to arrange road transport for the first of what has since been a long series of spectacular component deliveries, such as those of the machine's two magnetic coils each weighing 60 tonnes and measuring 7.2 metres in diameter. Above, one of them is seen passing through the village of Meyrin. The SC was commissioned in 1957 and was operational for 34 years!

  12. Voicing Consciousness: The Mind in Writing

    Science.gov (United States)

    Luce-Kapler, Rebecca; Catlin, Susan; Sumara, Dennis; Kocher, Philomene

    2011-01-01

    In this paper, the authors investigate the enduring power of voice as a concept in writing pedagogy. They argue that one can benefit from considering Elbow's assertion that both text and voice be considered as important aspects of written discourse. In particular, voice is a powerful metaphor for the material, social and historical nature of…

  13. Understanding the 'Anorexic Voice' in Anorexia Nervosa.

    Science.gov (United States)

    Pugh, Matthew; Waller, Glenn

    2016-07-20

    In common with individuals experiencing a number of disorders, people with anorexia nervosa report experiencing an internal 'voice'. The anorexic voice comments on the individual's eating, weight and shape and instructs the individual to restrict or compensate. However, the core characteristics of the anorexic voice are not known. This study aimed to develop a parsimonious model of the voice characteristics that are related to key features of eating disorder pathology and to determine whether patients with anorexia nervosa fall into groups with different voice experiences. The participants were 49 women with full diagnoses of anorexia nervosa. Each completed validated measures of the power and nature of their voice experience and of their responses to the voice. Different voice characteristics were associated with current body mass index, duration of disorder and eating cognitions. Two subgroups emerged, with 'weaker' and 'stronger' voice experiences. Those with stronger voices were characterized by having more negative eating attitudes, more severe compensatory behaviours, a longer duration of illness and a greater likelihood of having the binge-purge subtype of anorexia nervosa. The findings indicate that the anorexic voice is an important element of the psychopathology of anorexia nervosa. Addressing the anorexic voice might be helpful in enhancing outcomes of treatments for anorexia nervosa, but that conclusion might apply only to patients with more severe eating psychopathology. Copyright © 2016 John Wiley & Sons, Ltd.

  14. Voice and culture: A prospect theory approach

    NARCIS (Netherlands)

    Paddock, E.L.; Ko, Junsu; Cropanzano, R.; Bagger, J.; El Akremi, A.; Camerman, A.; Greguras, G. J.; Mladinic, A.; Moliner, C.; Nam, K.; Törnblom, K.; Van den Bos, Kees

    2015-01-01

    The present study examines the congruence of individuals' minimum preferred amounts of voice with the prospect theory value function across nine countries. Accounting for previously ignored minimum preferred amounts of voice and actual voice amounts integral to testing the steepness of gain and loss

  15. Finding Voice: Learning about Language and Power

    Science.gov (United States)

    Christensen, Linda

    2011-01-01

    Christensen discusses why teachers need to teach students "voice" in its social and political context, to show the intersection of voice and power, to encourage students to ask, "Whose voices get heard? Whose are marginalized?" As Christensen writes, "Once students begin to understand that Standard English is one language among many, we can help…

  16. Analyzing the mediated voice - a datasession

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    Broadcasted voices are technologically manipulated. In order to achieve a certain autencity or sound of “reality” paradoxically the voices are filtered and trained in order to reach the listeners. This “mis-en-scene” is important knowledge when it comes to the development of a consistent method o...... of analysis of the mediated voice...

  17. Analyzing the mediated voice - a datasession

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    Broadcasted voices are technologically manipulated. In order to achieve a certain autencity or sound of “reality” paradoxically the voices are filtered and trained in order to reach the listeners. This “mis-en-scene” is important knowledge when it comes to the development of a consistent method...... of analysis of the mediated voice...

  18. Voice and culture: A prospect theory approach

    NARCIS (Netherlands)

    Paddock, E.L.; Ko, Junsu; Cropanzano, R.; Bagger, J.; El Akremi, A.; Camerman, A.; Greguras, G. J.; Mladinic, A.; Moliner, C.; Nam, K.; Törnblom, K.; Van den Bos, Kees

    2015-01-01

    The present study examines the congruence of individuals' minimum preferred amounts of voice with the prospect theory value function across nine countries. Accounting for previously ignored minimum preferred amounts of voice and actual voice amounts integral to testing the steepness of gain and loss

  19. "Voice Forum" The Human Voice as Primary Instrument in Music Therapy

    DEFF Research Database (Denmark)

    Pedersen, Inge Nygaard; Storm, Sanne

    2009-01-01

    Aspects will be drawn on the human voice as tool for embodying our psychological and physiological state, and attempting integration of feelings. Presentations and dialogues on different methods and techniques in "Therapy related body-and voice work.", as well as the human voice as a tool for non...... for nonverbal orientation and information both to our selves and others. Focus on training on the voice instrument, the effect and impact of the human voice, and listening perspectives...

  20. Surgical management of an ACM aneurysm eight years after coiling.

    Science.gov (United States)

    Pogády, P; Fellner, F; Trenkler, J; Wurm, G

    2007-04-01

    The authors present a case report on rebleeding of a medial cerebral aneurysm (MCA) eight years after complete endovascular coiling. The primarily successfully coiled MCA aneurysm showed a local regrowth which, however, was not the source of the rebleeding. The angiogram demonstrated no evidence of contrast filling of the coiled segment, but according to intraoperative findings (haematoma location, displacement of coils, evident place of rupture) there is no doubt that the coiled segment of the aneurysm was responsible for the haemorrhage.

  1. Voice-Specialized Speech-Language Pathologist's Criteria for Discharge from Voice Therapy.

    Science.gov (United States)

    Gillespie, Amanda I; Gartner-Schmidt, Jackie

    2017-08-07

    No standard protocol exists to determine when a patient is ready and able to be discharged from voice therapy. The aim of the present study was to determine what factors speech-language pathologists (SLPs) deem most important when discharging a patient from voice therapy. A second aim was to determine if responses differed based on years of voice experience. Step 1: Seven voice-specialized SLPs generated a list of items thought to be relevant to voice therapy discharge. Step 2: Fifty voice-specialized SLPs rated each item on the list in terms of importance in determining discharge from voice therapy. Step 1: Four themes emerged-outcome measures, laryngeal appearance, SLP perceptions, and patient factors-as important items when determining discharge from voice therapy. Step 2: The top five most important criteria for discharge readiness were that the patient had to be able to (1) independently use a better voice (transfer), (2) function with his or her new voice production in activities of daily living (transfer), (3) differentiate between good and bad voice, (4) take responsibility for voice, and (5) sound better from baseline. Novice and experienced clinicians agreed between 94% and 97% concerning what was deemed "very important." SLPs agree that a patient's ability to use voice techniques in conversation and real-life situations outside of the therapy room are the most important determinants for voice therapy discharge. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  2. Reduction of metallic coil artefacts in computed tomography body imaging: effects of a new single-energy metal artefact reduction algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Kidoh, Masafumi; Utsunomiya, Daisuke; Ikeda, Osamu; Tamura, Yoshitaka; Oda, Seitaro; Yuki, Hideaki; Nakaura, Takeshi; Hirai, Toshinori; Yamashita, Yasuyuki [Kumamoto University, Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto (Japan); Funama, Yoshinori [Kumamoto University, Department of Medical Physics, Faculty of Life Sciences, Kumamoto (Japan); Kawano, Takayuki [Kumamoto University Graduate School, Department of Neurosurgery, Faculty of Life Sciences Research, Kumamoto (Japan)

    2016-05-15

    We evaluated the effect of a single-energy metal artefact reduction (SEMAR) algorithm for metallic coil artefact reduction in body imaging. Computed tomography angiography (CTA) was performed in 30 patients with metallic coils (10 men, 20 women; mean age, 67.9 ± 11 years). Non-SEMAR images were reconstructed with iterative reconstruction alone, and SEMAR images were reconstructed with the iterative reconstruction plus SEMAR algorithms. We compared image noise around metallic coils and the maximum diameters of artefacts from coils between the non-SEMAR and SEMAR images. Two radiologists visually evaluated the metallic coil artefacts utilizing a four-point scale: 1 = extensive; 2 = strong; 3 = mild; 4 = minimal artefacts. The image noise and maximum diameters of the artefacts of the SEMAR images were significantly lower than those of the non-SEMAR images (65.1 ± 33.0 HU vs. 29.7 ± 10.3 HU; 163.9 ± 54.8 mm vs. 10.3 ± 19.0 mm, respectively; P < 0.001). Better visual scores were obtained with the SEMAR technique (3.4 ± 0.6 vs. 1.0 ± 0.0, P < 0.001). The SEMAR algorithm significantly reduced artefacts caused by metallic coils compared with the non-SEMAR algorithm. This technique can potentially increase CT performance for the evaluation of post-coil embolization complications. (orig.)

  3. The development of the Spanish verb ir into auxiliary of voice

    DEFF Research Database (Denmark)

    Vinther, Thora

    2005-01-01

    spanish, syntax, grammaticalisation, past participle, passive voice, middle voice, language development......spanish, syntax, grammaticalisation, past participle, passive voice, middle voice, language development...

  4. Quench Protection of DI-BSCCO Coil

    Science.gov (United States)

    Yamaguchi, T.; Ueno, E.; Kato, T.; Hayashi, K.

    Quench protection is one of the most important requirements for the practical application of high-temperature-superconducting (HTS) coils. Quench protection requires that early detection of a developing quench event is followed by rapid reduction of the operating current. However, such quench detection is very difficult because HTS wire produces heat only locally due to the very slow propagation velocity of a normal zone. Excellent high voltage insulation performance is required if the current is to be reduced rapidly in a large-scale superconducting application with very large inductance. Thus it is important to investigate the behavior of coils with various decay time constants, and to detect voltages on very short time scales. This goal remains to be achieved. In the present study we built test coil and a full-scale pole coil for a 20 MW motor for use in experiments on quench protection, and parameterized the relation between the decay time constant and the detecting voltage, using a conventional balance circuit to detect the quench, which was generated by gradually raising the temperature of the coils. The results verify that a balance circuit can be used for quench detection. For example, when the current decay time constant is 4 seconds, the test coil can be protected even with a detecting voltage of 0.15 volts, despite a significant heat production rate of 126 W. We also confirmed that the full-scale pole coil, with a decay time constant of 20 seconds, can be protected with a detecting voltage of 0.06 V.

  5. Objective Voice Parameters in Colombian School Workers with Healthy Voices

    Directory of Open Access Journals (Sweden)

    Lady Catherine Cantor Cutiva

    2015-09-01

    Full Text Available Objectives: To characterize the objective voice parameters among school workers, and to identi­fy associated factors of three objective voice parameters, namely fundamental frequency, sound pressure level and maximum phonation time. Materials and methods: We conducted a cross-sectional study among 116 Colombian teachers and 20 Colombian non-teachers. After signing the informed consent form, participants filled out a questionnaire. Then, a voice sample was recorded and evaluated perceptually by a speech therapist and by objective voice analysis with praat software. Short-term environmental measurements of sound level, temperature, humi­dity, and reverberation time were conducted during visits at the workplaces, such as classrooms and offices. Linear regression analysis was used to determine associations between individual and work-related factors and objective voice parameters. Results: Compared with men, women had higher fundamental frequency (201 Hz for teachers and 209 for non-teachers vs. 120 Hz for teachers and 127 for non-teachers and sound pressure level (82 dB vs. 80 dB, and shorter maximum phonation time (around 14 seconds vs. around 16 seconds. Female teachers younger than 50 years of age evidenced a significant tendency to speak with lower fundamental frequen­cy and shorter mpt compared with female teachers older than 50 years of age. Female teachers had significantly higher fundamental frequency (66 Hz, higher sound pressure level (2 dB and short phonation time (2 seconds than male teachers. Conclusion: Female teachers younger than 50 years of age had significantly lower F0 and shorter mpt compared with those older than 50 years of age. The multivariate analysis showed that gender was a much more important determinant of variations in F0, spl and mpt than age and teaching occupation. Objectively measured temperature also contributed to the changes on spl among school workers.

  6. In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions

    NARCIS (Netherlands)

    Yang, J.

    2016-01-01

    This thesis presents another approach for direct cytosolic delivery via membrane fusion. This approach is based on a complementary pair of coiled-coil forming peptides, K (KIAALKE)4 and E (EIAALEK)4 and is mimicking the action of the SNARE-complex. The SNARE-complex is responsible for fusion between

  7. Growth Factor Tethering to Protein Nanoparticles via Coiled-Coil Formation for Targeted Drug Delivery.

    Science.gov (United States)

    Assal, Yasmine; Mizuguchi, Yoshinori; Mie, Masayasu; Kobatake, Eiry

    2015-08-19

    Protein-based nanoparticles are attractive carriers for drug delivery because they are biodegradable and can be genetically designed. Moreover, modification of protein-based nanoparticles with cell-specific ligands allows for active targeting abilities. Previously, we developed protein nanoparticles comprising genetically engineered elastin-like polypeptides (ELPs) with fused polyaspartic acid tails (ELP-D). Epidermal growth factor (EGF) was displayed on the surface of the ELP-D nanoparticles via genetic design to allow for active cell-targeting abilities. Herein, we focused on the coiled-coil structural motif as a means for noncovalent tethering of growth factor to ELP-D. Specifically, two peptides known to form a heterodimer via a coiled-coil structural motif were fused to ELP-D and single-chain vascular endothelial growth factor (scVEGF121), to facilitate noncovalent tethering upon formation of the heterodimer coiled-coil structure. Drug-loaded growth factor-tethered ELP-Ds were found to be effective against cancer cells by provoking cell apoptosis. These results demonstrate that tethering growth factor to protein nanoparticles through coiled-coil formation yields a promising biomaterial candidate for targeted drug delivery.

  8. An iterative method for coil sensitivity estimation in multi-coil MRI systems.

    Science.gov (United States)

    Ling, Qiang; Li, Zhaohui; Song, Kaikai; Li, Feng

    2014-12-01

    This paper presents an iterative coil sensitivity estimation method for multi-coil MRI systems. The proposed method works with coil images in the magnitude image domain. It determines a region of support (RoS), a region being composed of the same type of tissues, by a region growing algorithm, which makes use of both intensities and intensity gradients of pixels. By repeating this procedure, it can determine multiple regions of support, which together cover most of the concerned image area. The union of these regions of support provides a rough estimate of the sensitivity of each coil through dividing the intensities of pixels by the average intensity inside every region of support. The obtained rough coil sensitivity estimate is further approached with the product of multiple low-order polynomials, rather than a single one. The product of these polynomials provides a smooth estimate of the sensitivity of each coil. With the obtained sensitivities of coils, it can produce a better reconstructed image, which determines more correct regions of support and yields preciser estimates of the sensitivities of coils. In other words, the method can be iteratively implemented to improve the estimation performance. The proposed method was verified through both simulated data and clinical data from different body parts. The experimental results confirm the superiority of our method to some conventional methods.

  9. A coiled-coil domain acts as a molecular ruler in LPS chain length regulation

    Science.gov (United States)

    Tuukkanen, Anne; Danciu, Iulia; Svergun, Dmitri I.; Hussain, Rohanah; Liu, Huanting; Whitfield, Chris; Naismith, James H.

    2014-01-01

    Long-chain bacterial polysaccharides play important roles in pathogenicity. In Escherichia coli O9a, a model for ABC transporter dependent polysaccharide assembly, a large extracellular carbohydrate with a narrow distribution of size is polymerized from monosaccharides by a complex of two proteins, WbdA (polymerase) and WbdD (terminating protein). Such careful control of polymerization is recurring theme in biology. Combining crystallography and small angle X-ray scattering, we show that the C-terminal domain of WbdD contains an extended coiled-coil that physically separates WbdA from the catalytic domain of WbdD. The effects of insertions and deletions within the coiled-coil region were analyzed in vivo, revealing that polymer size is controlled by varying the length of the coiled-coil domain. Thus, the coiled-coil domain of WbdD functions as a molecular ruler that, along with WbdA:WbdD stoichiometry, controls the chain length of a model bacterial polysaccharide. PMID:25504321

  10. Minimax current density gradient coils: analysis of coil performance and heating.

    Science.gov (United States)

    Poole, Michael S; While, Peter T; Lopez, Hector Sanchez; Crozier, Stuart

    2012-08-01

    Standard gradient coils are designed by minimizing the inductance or resistance for an acceptable level of gradient field nonlinearity. Recently, a new method was proposed to minimize the maximum value of the current density in a coil additionally. The stated aim of that method was to increase the minimum wire spacing and to reduce the peak temperature in a coil for fixed efficiency. These claims are tested in this study with experimental measurements of magnetic field and temperature as well as simulations of the performance of many coils. Experimental results show a 90% increase in minimum wire spacing and 40% reduction in peak temperature for equal coil efficiency and field linearity. Simulations of many more coils indicate increase in minimum wire spacing of between 50 and 340% for the coils studied here. This method is shown to be able to increase coil efficiency when constrained by minimum wire spacing rather than switching times or total power dissipation. This increase in efficiency could be used to increase gradient strength, duty cycle, or buildability.

  11. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

    NARCIS (Netherlands)

    Sinka, Rita; Gillingham, Alison K.; Kondylis, Vangelis; Munro, Sean

    2008-01-01

    Vesicles and other carriers destined for the Golgi apparatus must be guided to the correct cisternae. Golgins, long coiled-coil proteins that localize to particular Golgi subdomains via their C termini, are candidate regulators of vesicle sorting. In this study, we report that the GRIP domain

  12. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

    NARCIS (Netherlands)

    Sinka, Rita; Gillingham, Alison K.; Kondylis, Vangelis; Munro, Sean

    2008-01-01

    Vesicles and other carriers destined for the Golgi apparatus must be guided to the correct cisternae. Golgins, long coiled-coil proteins that localize to particular Golgi subdomains via their C termini, are candidate regulators of vesicle sorting. In this study, we report that the GRIP domain golgin

  13. Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide

    NARCIS (Netherlands)

    Pagel, K; Seeger, K; Seiwert, B; Villa, Alessandra; Mark, AE; Berger, S; Koksch, B

    2005-01-01

    We report here an advanced approach for the characterization of the folding pattern of a de novo designed antiparallel coiled coil peptide by high-resolution methods. Incorporation of two fluorescence labels at the C- and N-terminus of the peptide chain as well as modi. cation of two hydrophobic cor

  14. A high-resolution structure that provides insight into coiled-coil thiodepsipeptide dynamic chemistry.

    Science.gov (United States)

    Dadon, Zehavit; Samiappan, Manickasundaram; Shahar, Anat; Zarivach, Raz; Ashkenasy, Gonen

    2013-09-16

    Stable and reactive: A crystal structure at 1.35 Å of a thioester coiled-coil protein reveals high similarity to all-peptide-bond proteins. In these assemblies, the thioester bonds are kept reactive towards thiol molecules in the mixture. This enables efficient domain exchange between proteins in response to changes in folding conditions or introduction of external templates.

  15. Allosteric effects in coiled-coil proteins folding and lanthanide-ion binding.

    Science.gov (United States)

    Samiappan, Manickasundaram; Alasibi, Samaa; Cohen-Luria, Rivka; Shanzer, Abraham; Ashkenasy, Gonen

    2012-10-07

    Peptide sequences modified with lanthanide-chelating groups at their N-termini, or at their lysine side chains, were synthesized, and new Ln(III) complexes were characterized. We show that partial folding of the conjugates to form trimer coiled coil structures induces coordination of lanthanides to the ligand, which in turn further stabilizes the 3D structure.

  16. Playful Interaction with Voice Sensing Modular Robots

    DEFF Research Database (Denmark)

    Heesche, Bjarke; MacDonald, Ewen; Fogh, Rune

    2013-01-01

    This paper describes a voice sensor, suitable for modular robotic systems, which estimates the energy and fundamental frequency, F0, of the user’s voice. Through a number of example applications and tests with children, we observe how the voice sensor facilitates playful interaction between...... children and two different robot configurations. In future work, we will investigate if such a system can motivate children to improve voice control and explore how to extend the sensor to detect emotions in the user’s voice....

  17. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xiufang [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Nie, Xinyi [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Liang, Yilang [School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Lu, Falong [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Yan, Zhongming, E-mail: wangxiufanghappy@163.com [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Wang, Yu [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China)

    2017-01-15

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  18. VOICE QUALITY BEFORE AND AFTER THYROIDECTOMY

    Directory of Open Access Journals (Sweden)

    Dora CVELBAR

    2016-04-01

    Full Text Available Introduction: Voice disorders are a well-known complication which is often associated with thyroid gland diseases and because voice is still the basic mean of communication it is very important to maintain its quality healthy. Objectives: The aim of this study referred to questions whether there is a statistically significant difference between results of voice self-assessment, perceptual voice assessment and acoustic voice analysis before and after thyroidectomy and whether there are statistically significant correlations between variables of voice self-assessment, perceptual assessment and acoustic analysis before and after thyroidectomy. Methods: This scientific research included 12 participants aged between 41 and 76. Voice self-assessment was conducted with the help of Croatian version of Voice Handicap Index (VHI. Recorded reading samples were used for perceptual assessment and later evaluated by two clinical speech and language therapists. Recorded samples of phonation were used for acoustic analysis which was conducted with the help of acoustic program Praat. All of the data was processed through descriptive statistics and nonparametric statistical methods. Results: Results showed that there are statistically significant differences between results of voice self-assessments and results of acoustic analysis before and after thyroidectomy. Statistically significant correlations were found between variables of perceptual assessment and acoustic analysis. Conclusion: Obtained results indicate the importance of multidimensional, preoperative and postoperative assessment. This kind of assessment allows the clinician to describe all of the voice features and provides appropriate recommendation for further rehabilitation to the patient in order to optimize voice outcomes.

  19. Beyond Insularity: Releasing the Voices.

    Science.gov (United States)

    Greene, Maxine

    1993-01-01

    Aspects of English-as-a-Second-Language are discussed from the standpoint of a teacher-educator with a particular interest in philosophy, the arts, and humanities and what they signify for the schools. The idea of giving voice to all viewpoints and sociocultural circumstances is considered for content learning and heterogeneous grouping. (Contains…

  20. A voice and nothing more

    DEFF Research Database (Denmark)

    Mebus, Andreas Nozic Lindgren

    2012-01-01

    Andreas Mebus fokuserer herefter på et helt konkret aspekt af talen, nemlig ”stemmen” i sin artikel ”A voice and nothing more – en filosofisk udredning af stemmen”. Gennem Mladen Dolars teori om stemmen, redegør Mebus for de forskellige aspekter ved stemmen; som bærer af mening, som æstetisk...

  1. Voice, Citizenship, and Civic Action

    DEFF Research Database (Denmark)

    Tufte, Thomas

    2014-01-01

    In recent years the world has experienced a resurgence in practices of bottom-up communication for social change, a plethora of agency in which claims for voice and citizenship through massive civic action have conquered center stage in the public debate. This resurgence has sparked a series...

  2. FILTWAM and Voice Emotion Recognition

    NARCIS (Netherlands)

    Bahreini, Kiavash; Nadolski, Rob; Westera, Wim

    2014-01-01

    This paper introduces the voice emotion recognition part of our framework for improving learning through webcams and microphones (FILTWAM). This framework enables multimodal emotion recognition of learners during game-based learning. The main goal of this study is to validate the use of microphone d

  3. The Performing Voice of Radio

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    The ongoing international development of opening media archives for researchers as well as for broader audiences calls for a closer discussion of the mediated voice and how to analyse it. Which parameters can be analysed and which parameters are not covered by the analysis? Furthermore, how do we...

  4. Voice and choice by delegation

    NARCIS (Netherlands)

    van de Bovenkamp, H.; Vollaard, H.; Trappenburg, M.; Grit, K

    2013-01-01

    In many Western countries, options for citizens to influence public services are increased to improve the quality of services and democratize decision making. Possibilities to influence are often cast into Albert Hirschman's taxonomy of exit (choice), voice, and loyalty. In this article we identify

  5. Work-related voice disorder

    Directory of Open Access Journals (Sweden)

    Paulo Eduardo Przysiezny

    2015-04-01

    Full Text Available INTRODUCTION: Dysphonia is the main symptom of the disorders of oral communication. However, voice disorders also present with other symptoms such as difficulty in maintaining the voice (asthenia, vocal fatigue, variation in habitual vocal fundamental frequency, hoarseness, lack of vocal volume and projection, loss of vocal efficiency, and weakness when speaking. There are several proposals for the etiologic classification of dysphonia: functional, organofunctional, organic, and work-related voice disorder (WRVD.OBJECTIVE: To conduct a literature review on WRVD and on the current Brazilian labor legislation.METHODS: This was a review article with bibliographical research conducted on the PubMed and Bireme databases, using the terms "work-related voice disorder", "occupational dysphonia", "dysphonia and labor legislation", and a review of labor and social security relevant laws.CONCLUSION: WRVD is a situation that frequently is listed as a reason for work absenteeism, functional rehabilitation, or for prolonged absence from work. Currently, forensic physicians have no comparative parameters to help with the analysis of vocal disorders. In certain situations WRVD may cause, work disability. This disorder may be labor-related, or be an adjuvant factor to work-related diseases.

  6. The Performing Voice of Radio

    DEFF Research Database (Denmark)

    Lawaetz, Anna

    The ongoing international development of opening media archives for researchers as well as for broader audiences calls for a closer discussion of the mediated voice and how to analyse it. Which parameters can be analysed and which parameters are not covered by the analysis? Furthermore, how do we...

  7. Adolescent Leadership: The Female Voice

    Science.gov (United States)

    Archard, Nicole

    2013-01-01

    This research investigated the female adolescent view of leadership by giving voice to student leaders through focus group discussions. The questions: What is leadership? Where/how was leadership taught?, and How was leadership practised? were explored within the context of girls' schools located in Australia, with one school located in South…

  8. FILTWAM and Voice Emotion Recognition

    NARCIS (Netherlands)

    Bahreini, Kiavash; Nadolski, Rob; Westera, Wim

    2014-01-01

    This paper introduces the voice emotion recognition part of our framework for improving learning through webcams and microphones (FILTWAM). This framework enables multimodal emotion recognition of learners during game-based learning. The main goal of this study is to validate the use of microphone

  9. Voicing children's critique and utopias

    DEFF Research Database (Denmark)

    Husted, Mia; Lind, Unni

    2016-01-01

    , designed to accommodate children's participation through graphic illustrations of young children's critique and utopias. The study is informed by a commitment to democratic participation and processes (Reason and Bradbury 2001, Gunnarsson et al. 2016). Ethical guidelines implied dialogues and discussions......, children's voice, critique and utopias, pedagogical work...

  10. Women's Voices in Experiential Education.

    Science.gov (United States)

    Warren, Karen, Ed.

    This book is a collection of feminist analyses of various topics in experiential education, particularly as it applies to outdoors and adventure education, as well as practical examples of how women's experiences can contribute to the field as a whole. Following an introduction, "The Quilt of Women's Voices" (Maya Angelou), the 25…

  11. Baculovirus FP25K Localization: Role of the Coiled-Coil Domain.

    Science.gov (United States)

    Garretson, Tyler A; McCoy, Jason C; Cheng, Xiao-Wen

    2016-11-01

    Two types of viruses are produced during the baculovirus life cycle: budded virus (BV) and occlusion-derived virus (ODV). A particular baculovirus protein, FP25K, is involved in the switch from BV to ODV production. Previously, FP25K from the model alphabaculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) was shown to traffic ODV envelope proteins. However, FP25K localization and the domains involved are inconclusive. Here we used a quantitative approach to study FP25K subcellular localization during infection using an AcMNPV bacmid virus that produces a functional AcMNPV FP25K-green fluorescent protein (GFP) fusion protein. During cell infection, FP25K-GFP localized primarily to the cytoplasm, particularly amorphous structures, with a small fraction being localized in the nucleus. To investigate the sequences involved in FP25K localization, an alignment of baculovirus FP25K sequences revealed that the N-terminal putative coiled-coil domain is present in all alphabaculoviruses but absent in betabaculoviruses. Structural prediction indicated a strong relatedness of AcMNPV FP25K to long interspersed element 1 (LINE-1) open reading frame 1 protein (ORF1p), which contains an N-terminal coiled-coil domain responsible for cytoplasmic retention. Point mutations and deletions of this domain lead to a change in AcMNPV FP25K localization from cytoplasmic to nuclear. The coiled-coil and C-terminal deletion viruses increased BV production. Furthermore, a betabaculovirus FP25K protein lacking this N-terminal coiled-coil domain localized predominantly to the nucleus and exhibited increased BV production. These data suggest that the acquisition of this N-terminal coiled-coil domain in FP25K is important for the evolution of alphabaculoviruses. Moreover, with the divergence of preocclusion nuclear membrane breakdown in betabaculoviruses and membrane integrity in alphabaculoviruses, this domain represents an alphabaculovirus adaptation for nuclear trafficking

  12. Temporal voice areas exist in autism spectrum disorder but are dysfunctional for voice identity recognition

    Science.gov (United States)

    Borowiak, Kamila; von Kriegstein, Katharina

    2016-01-01

    The ability to recognise the identity of others is a key requirement for successful communication. Brain regions that respond selectively to voices exist in humans from early infancy on. Currently, it is unclear whether dysfunction of these voice-sensitive regions can explain voice identity recognition impairments. Here, we used two independent functional magnetic resonance imaging studies to investigate voice processing in a population that has been reported to have no voice-sensitive regions: autism spectrum disorder (ASD). Our results refute the earlier report that individuals with ASD have no responses in voice-sensitive regions: Passive listening to vocal, compared to non-vocal, sounds elicited typical responses in voice-sensitive regions in the high-functioning ASD group and controls. In contrast, the ASD group had a dysfunction in voice-sensitive regions during voice identity but not speech recognition in the right posterior superior temporal sulcus/gyrus (STS/STG)—a region implicated in processing complex spectrotemporal voice features and unfamiliar voices. The right anterior STS/STG correlated with voice identity recognition performance in controls but not in the ASD group. The findings suggest that right STS/STG dysfunction is critical for explaining voice recognition impairments in high-functioning ASD and show that ASD is not characterised by a general lack of voice-sensitive responses. PMID:27369067

  13. First full-size ATLAS barrel toroid coil successfully tested up to 22 kA at 4 T

    CERN Document Server

    Dudarev, A; Benoit, P; Berriaud, C P; Broggi, F; Deront, L; Foussat, A; Junker, S; ten Kate, H H J; Kopeykin, N; Olesen, G; Olyunin, A; Pengo, R; Rabbers, J J; Ravat, S; Rey, J M; Sbrissa, E; Shugaev, I; Stepanov, V; Védrine, P; Volpini, Giovanni

    2005-01-01

    The Superconducting Barrel Toroid is providing (together with the two End-Cap Toroids not presented here) the magnetic field for the muon detectors in the ATLAS Experiment at the LHC at CERN. The toroid with outer dimensions of 25 m length and 20 m diameter, is built up from 8 identical racetrack coils. The coils with 120 turns each are wound with an aluminum stabilized NbTi conductor and operate at 20.5 kA at 3.9 T local field in the windings and is conduction cooled at 4.8 K by circulating forced flow helium in cooling tubes attached to the cold mass. The 8 coils of 25 m * 5 m are presently under construction and the first coils have already been fully integrated and tested. Meanwhile the assembly of the toroid 100 m underground in the ATLAS cavern at CERN has started. The 8 coils are individually tested on surface before installation. In this paper the test of the first coil, unique in size and manufacturing technology, is described in detail and the results are compared to the previous experience with the...

  14. Initial feasibility testing of limited field of view magnetic resonance thermometry using a local cardiac radiofrequency coil.

    Science.gov (United States)

    Volland, Nelly A; Kholmovski, Eugene G; Parker, Dennis L; Hadley, J Rock

    2013-10-01

    The visualization of lesion formation in real time is one potential benefit of carrying out radiofrequency ablation under magnetic resonance (MR) guidance in the treatment of atrial fibrillation. MR thermometry has the potential to detect such lesions. However, performing MR thermometry during cardiac radiofrequency ablation requires high temporal and spatial resolution and a high signal-to-noise ratio. In this study, a local MR coil (2-cm diameter) was developed to investigate the feasibility of performing limited field of view MR thermometry with high accuracy and speed. The local MR coil allowed high-resolution (1 × 1 × 3 mm(3)) image acquisitions in 76.3 ms with a field of view 64 × 32 mm(2) during an open-chest animal experiment. This represents a 4-fold image acquisition acceleration and an 18-fold field of view reduction compared to that achieved using external MR coils. The signal sensitivity achieved using the local coil was over 20 times greater than that achievable using external coils with the same scan parameters. The local coil configuration provided fewer artifacts and sharper and more stable images. These results demonstrate that MR thermometry can be performed in the heart wall and that lesion formation can be observed during radiofrequency ablation procedures in a canine model. Copyright © 2012 Wiley Periodicals, Inc.

  15. A cradle-shaped gradient coil to expand the clear-bore width of an animal MRI scanner.

    Science.gov (United States)

    Gilbert, K M; Gati, J S; Klassen, L M; Menon, R S

    2010-01-21

    The never ending quest for higher magnetic field strengths in MRI and MRS has led to small and medium bore scanners at 9.4 T and above for both human and animal use; however, these bore diameters restrict the size of object that can be accommodated when using a conventional gradient coil. By replacing a cylindrical gradient-coil insert with a single-sided gradient coil, the scanner's functionality can be extended to include localized imaging of wider samples. As a prototype, a three-axis, cradle-shaped gradient coil was designed, fabricated and implemented in a 9.4 T animal MRI scanner. Since gradient fields are required only to be monotonic over the desired field of view, the cradle gradient coil was designed to produce high gradient efficiencies (up to 2.25 mT m(-1) A(-1) over a 5 cm imaging region) at the expense of gradient linearity. A dedicated three-dimensional algorithm was developed to correct the resultant image distortion. Preliminary images of a grid phantom and a mouse demonstrated the fidelity of the algorithm in correcting image distortion of greater than 200%. Eddy currents were measured along each gradient axis. A large 65.2 (Hz mT(-1) m) B(0) eddy current was produced by the y-axis, suggesting potential limitations of single-sided gradient coils.

  16. Critical current studies of a HTS rectangular coil

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Z. [Department of Engineering, University of Cambridge (United Kingdom); Chudy, M., E-mail: Michal.chudy@stuba.sk [Graduate School of Technology Management, University of Pretoria (South Africa); Institute of Power and Applied Electrical Engineering, Slovak University of Technology in Bratislava (Slovakia); Ruiz, H.S. [Department of Engineering, University of Leicester, Leicester LE1 7RH (United Kingdom); Zhang, X.; Coombs, T. [Department of Engineering, University of Cambridge (United Kingdom)

    2017-05-15

    Highlights: • Unique square pancake coil was manufactured. • Measurements in relatively high magnetic field were performed. • Different sections of the coil were characterized. • Parts of the coil which are limiting critical current were identified. - Abstract: Nowadays, superconducting high field magnets are used in numerous applications due to their superior properties. High temperature superconductors (HTS) are usually used for production of circular pancake or racetrack coils. However different geometries of HTS coils might be required for some specific applications. In this study, the HTS coil wound on a rectangular frame was fully characterized in homogeneous DC background field. The study contains measurements of critical current angular dependencies. The critical current of the entire coil and two selected strands under different magnitudes and orientations of external magnetic fields are measured. The critical regions of the coil in different angular regimes are determined. This study brings better understanding of the in- field performance of HTS coils wound on frames with right-angles.

  17. Wireless power transmission applied the mutual coupling between coils

    Science.gov (United States)

    Furuta, Kenta; Baba, Ryouichi; Shun, Endo; Nunokawa, Kazuki; Takahashi, Wataru; Maruyama, Tamami

    2017-07-01

    Recently, the studies of wireless power transfer (WPT) to electric vehicles in motion on the snow-piled road have been reported. In WPT by magnetic field resonance method, transmission coefficient S21, which is one of the scattering parameters, from transmission coil to received coil are degraded because of misalignment of transmitting and receiving coil, the distance between these coils, and the effects of the ice and snow. This paper adopts parasitic coil as a solution to improve the reception power in which the parasitic coil is inserted between transmitting and receiving coils. Analysis and experimental results show that parasitic coil could improve the value of S21 by 15 dB using mutual coupling. LED could be light by this solution when the distance between transmitting and receiving coils are 150 mm.

  18. Clinical course of a partially thrombosed, symptomatic aneurysm of the basilar artery tip with partial recanalization subsequent to coiling; Verlaufsbeschreibung eines teilthrombosierten symptomatischen Basilariskopfaneurysmas mit teilweiser Rekanalisierung nach Coiling

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, V. [Universitaet des Saarlandes, Abteilung fuer Neuroradiologie, Homburg (Germany); Klinikum Saarbruecken, Institut fuer bildgebende Diagnostik und Interventionen, Saarbruecken (Germany); Axmann, C.; Reith, W. [Universitaet des Saarlandes, Abteilung fuer Neuroradiologie, Homburg (Germany)

    2006-05-15

    A 72-year-old patient was referred to the neuroradiological department for diagnostic angiography. She was suffering from vertigo and double vision. Magnetic resonance imaging performed elsewhere had demonstrated a giant aneurysm of the basilar artery tip 2 cm in diameter. Angiography revealed a large aneurysm with a broad neck that was partially thrombosed, which precluded closure by coiling. Neurosurgical management by clipping also appeared to be unsuitable because of the proximity to the cerebrum. The decision was reached to proceed expectantly by closely monitoring the clinical course. When the aneurysm increased in size in the ensuing weeks, coiling was performed successfully. Angiographic follow-up showed reperfusion of the aneurysm neck and closure was again achieved by repeat coiling. Reperfusion is not a rare complication following coiling and often necessitates renewed intervention. (orig.) [German] Eine 72-jaehrige Patientin wurde in der neuroradiologischen Abteilung zur diagnostischen Angiographie vorgestellt. Sie litt unter Schwindel und Doppelbildern. Eine auswaertige MR-Untersuchung des Gehirns zeigte ein Riesenaneurysma des Basilariskopfes mit einem Durchmesser von 2 cm. Die Angiographie zeigte ein grosses Aneurysma mit breitem Hals, das teilweise thrombosiert war. Dies liess einen Verschluss durch Coiling nicht zu. Eine neurochirurgische Behandlung durch Klippung erschien wegen der Naehe zum Mittelhirn ebenfalls ungeeignet. Man einigte sich auf ein abwartendes Vorgehen durch eine engmaschige Verlaufsbeobachtung. Als das Aneurysma in den folgenden Wochen eine Groessenzunahme zeigte, wurde erfolgreich ein Coiling durchgefuehrt. Eine angiographische Verlaufskontrolle zeigte eine Reperfusion des Aneurysmahalses. Erneut konnte ein Verschluss durch Coiling erzielt werden. Eine Reperfusion ist keine seltene Komplikation nach Coiling, die oft eine erneute Intervention erfordert. (orig.)

  19. MWD tool for deep, small diameter boreholes

    Energy Technology Data Exchange (ETDEWEB)

    Buytaert, J.P.R.; Duckworth, A.

    1992-03-17

    This patent describes an apparatus for measuring a drilling parameters while drilling a borehole in an earth formation, wherein the borehole includes a small diameter deep borehole portion and a large diameter upper borehole portion. It includes small diameter drillstring means for drilling the deep borehole portion; sensor means, disposed within the small diameter drillstring means, for measuring a drilling parameter characteristic of the deep portion of the borehole while drilling the deep portion of the borehole and for providing sensor output signals indicative of the measured parameter; an upper drillstring portion extending between the surface of the formation and the small diameter drillstring means, the upper drillstring portion including a large diameter drillstring portion; data transmission means disposed within the large diameter drillstring portion and responsive to the sensor output.

  20. Surface Coil for Magnetic Resonance Imaging

    Directory of Open Access Journals (Sweden)

    Beatriz Taimy Ricardo Ferro

    2015-01-01

    Full Text Available Currently Magnetic Resonance Imaging (MRI, has become a vital tool for the clinical diagnosis of various diseases, especially in the Nervisos Central System and the Musculos keletal System. Coils(RF are an essential component in the generation of these images, are responsible for exciting thespins of nuclei in a sample and/or detect the resultant signal coming from them. The use of surface RF coils has increased considerably, because they have a high signal to noise ratio, a parameter that defines the quality of the image. In the present work, there was realized the theoretical design and practical implementation of a circular surface RF coil. The experimental prototype was optimized to be used in the tomograph Giroimag03  built in Medical Biophysics Center

  1. Determination of Coil Inductances Cylindrical Iron Nucleus

    Directory of Open Access Journals (Sweden)

    Azeddine Mazouz

    2014-03-01

    Full Text Available The paper describes the investigation and development of a structure and performance characteristics of a coil iron nucleus cylindrical (C.I.N.C. The coil iron nucleus cylindrical is a nonlinear electro radio in which the moving of the nucleus in a sense or in other causes change in inductance and can reach extreme values at the superposition of nucleus and coil centers. The variation of the inductance and the degree of freedom of movement of the nucleus can lead to a device with electromechanical conversion The aim of this paper is the determination and visualization of self inductance and mutual of the (C.I.N.C based on geometric dimensions and the displacement of the nucleus.  

  2. CS model coil experimental log book

    Energy Technology Data Exchange (ETDEWEB)

    Nishijima, Gen; Sugimoto, Makoto; Nunoya, Yoshihiko; Wakabayashi, Hiroshi; Tsuji, Hiroshi [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2001-02-01

    Charging test of the ITER CS Model Coil which is the world's largest superconducting pulse coil and the CS Insert Coil had started at April 11, 2000 and had completed at August 18, 2000. In the campaign, total shot numbers were 356 and the size of the data file in the DAS (Data Acquisition System) was over 20 GB. This report is a database that consists of the log list and the log sheets of every shot. One can access the database, make a search, and browse results via Internet (http://1ogwww.naka.jaeri.go.jp). The database will be useful to quick search to choose necessary shots. (author)

  3. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu

    2014-11-13

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  4. Measuring the orthogonality error of coil systems

    Science.gov (United States)

    Heilig, B.; Csontos, A.; Pajunpää, K.; White, Tim; St. Louis, B.; Calp, D.

    2012-01-01

    Recently, a simple method was proposed for the determination of pitch angle between two coil axes by means of a total field magnetometer. The method is applicable when the homogeneous volume in the centre of the coil system is large enough to accommodate the total field sensor. Orthogonality of calibration coil systems used for calibrating vector magnetometers can be attained by this procedure. In addition, the method can be easily automated and applied to the calibration of delta inclination–delta declination (dIdD) magnetometers. The method was tested by several independent research groups, having a variety of test equipment, and located at differing geomagnetic observatories, including: Nurmijärvi, Finland; Hermanus, South Africa; Ottawa, Canada; Tihany, Hungary. This paper summarizes the test results, and discusses the advantages and limitations of the method.

  5. Resistive demountable toroidal-field coils for tokamak reactors

    Energy Technology Data Exchange (ETDEWEB)

    Jassby, D.L.; Jacobsen, R.A.; Kalnavarns, J.; Masson, L.S.; Sekot, J.P.

    1981-07-01

    Readily demountable TF (toroidal-field) coils allow complete access to the internal components of a tokamak reactor for maintenance of replacement. The requirement of readily demountable joints dictates the use of water-cooled resistive coils, which have a host of decisive advantages over superconducting coils. Previous papers have shown that resistive TF coils for tokamak reactors can operate in the steady state with acceptable power dissipation (typically, 175 to 300 MW). This paper summarizes results of parametric studies of size optimization of rectangular TF coils and of a finite-element stress analysis, and examines several candidate methods of implementing demountable joints for rectangular coils constructed of plate segments.

  6. Analytical and experimental analysis of tube coil heat exchanger

    Science.gov (United States)

    Smusz, R.

    2016-09-01

    The paper presents the analytical and experimental analysis of heat transfer for the finned tube coil heat exchanger immersed in thermal storage tank. The tank is equipped with three helical-shaped heating coils and cylindrical- shaped stratification device. Two coils, upper and lower, use the water as a heating medium. The third, double wall heat exchanger coil, located at the bottom head on the tank is filled by the refrigerant (freon). Calculations of thermal power of water coil were made. Correlations of heat transfer coefficients in curved tubes were applied. In order to verify the analytical calculations the experimental studies of heat transfer characteristic for coil heat exchanger were performed.

  7. Final design and construction of the Wendelstein7-X coils

    Energy Technology Data Exchange (ETDEWEB)

    Wegener, L. E-mail: lutz.wegener@ipp.mpg.de; Feist, J.-H.; Sapper, J.; Kerl, F.; Werner, F

    2001-11-01

    The Stellarator of the Wendelstein 7-X (W7-X) experiment contains a system of 50 non-planar and 20 planar superconducting coils. The coils were designed by the IPP. The coil manufacturing and inspection is shared between several European enterprises and consortiums. The coils consist of the winding pack embedded in a stainless steel casing and of the related instrumentation. Design details, tolerances and guarantee values and differences between the coils types are described in the contribution. The features of the superconductor are described separately. Finally, the contribution indicates measures adopted by the W7-X project to ensure the quality of the coil design and manufacturing.

  8. Endosphenoidal coil for intraoperative magnetic resonance imaging of the pituitary gland during transsphenoidal surgery.

    Science.gov (United States)

    Chittiboina, Prashant; Lalith Talagala, S; Merkle, Hellmut; Sarlls, Joelle E; Montgomery, Blake K; Piazza, Martin G; Scott, Gretchen; Ray-Chaudhury, Abhik; Lonser, Russell R; Oldfield, Edward H; Koretsky, Alan P; Butman, John A

    2016-12-01

    OBJECTIVE Pituitary MR imaging fails to detect over 50% of microadenomas in Cushing's disease and nearly 80% of cases of dural microinvasion. Surface coils can generate exceptionally high-resolution images of the immediately adjacent tissues. To improve imaging of the pituitary gland, a receive-only surface coil that can be placed within the sphenoid sinus (the endosphenoidal coil [ESC]) during transsphenoidal surgery (TSS) was developed and assessed. METHODS Five cadaver heads were used for preclinical testing of the ESC. The ESC (a double-turn, 12-mm-diameter surface coil made from 1-mm-diameter copper wire) was developed to obtain images in a 1.5-T MR scanner. The ESC was placed (via a standard sublabial TSS approach) on the anterior sella face. Clinical MR scans were obtained using the 8-channel head coil and ESC as the receiver coils. Using the ESC, ultra-high-resolution, 3D, balanced fast field echo (BFFE) and T1-weighted imaging were performed at resolutions of 0.25 × 0.25 × 0.50 mm(3) and 0.15 × 0.15 × 0.30 mm(3), respectively. RESULTS Region-of-interest analysis indicated a 10-fold increase in the signal-to-noise ratio (SNR) of the pituitary when using the ESC compared with the 8-channel head coil. ESC-related improvements (p < 0.01) in the SNR were inversely proportional to the distance from the ESC tip to the anterior pituitary gland surface. High-resolution BFFE MR imaging obtained using ESC revealed a number of anatomical features critical to pituitary surgery that were not visible on 8-channel MR imaging, including the pituitary capsule, the intercavernous sinus, and microcalcifications in the pars intermedia. These ESC imaging findings were confirmed by the pathological correlation with whole-mount pituitary sections. CONCLUSIONS ESC can significantly improve SNR in the sellar region intraoperatively using current 1.5-T MR imaging platforms. Improvement in SNR can provide images of the sella and surrounding structures with unprecedented

  9. The outer vactank, an object of 7.6m diameter and 13m length is built up of three cylindrical parts. The central part that is integral part of the central barrel and the the extension on either side each one 4.5m long. These extensions house the shoulders that will support and prestress the CMS Coil. To weld the extensions onto the central part a full penetration weld of 24m length and 45 mm thickness has to be done by hand from inside and outside the vacuum tank and its deformation is controled permanently.

    CERN Multimedia

    Hubert Gerwig

    2001-01-01

    The outer vacuum tank will hold the coil suspension system and transmits the weight of the inner detectors to the central barrel. Its thickness is staggered. In the central part its thickness is 60 mm and then goes down to 30 mm at the extremity.

  10. Coiled coil interactions for the targeting of liposomes for nucleic acid delivery

    Science.gov (United States)

    Oude Blenke, Erik E.; van den Dikkenberg, Joep; van Kolck, Bartjan; Kros, Alexander; Mastrobattista, Enrico

    2016-04-01

    Coiled coil interactions are strong protein-protein interactions that are involved in many biological processes, including intracellular trafficking and membrane fusion. A synthetic heterodimeric coiled-coil forming peptide pair, known as E3 (EIAALEK)3 and K3 (KIAALKE)3 was used to functionalize liposomes encapsulating a splice correcting oligonucleotide or siRNA. These peptide-functionalized vesicles are highly stable in solution but start to cluster when vesicles modified with complementary peptides are mixed together, demonstrating that the peptides quickly coil and crosslink the vesicles. When one of the peptides was anchored to the cell membrane using a hydrophobic cholesterol anchor, vesicles functionalized with the complementary peptide could be docked to these cells, whereas non-functionalized cells did not show any vesicle tethering. Although the anchored peptides do not have a downstream signaling pathway, microscopy pictures revealed that after four hours, the majority of the docked vesicles were internalized by endocytosis. Finally, for the first time, it was shown that the coiled coil assembly at the interface between the vesicles and the cell membrane induces active uptake and leads to cytosolic delivery of the nucleic acid cargo. Both the siRNA and the splice correcting oligonucleotide were functionally delivered, resulting respectively in the silencing or recovery of luciferase expression in the appropriate cell lines. These results demonstrate that the docking to the cell by coiled coil interaction can induce active uptake and achieve the successful intracellular delivery of otherwise membrane impermeable nucleic acids in a highly specific manner.Coiled coil interactions are strong protein-protein interactions that are involved in many biological processes, including intracellular trafficking and membrane fusion. A synthetic heterodimeric coiled-coil forming peptide pair, known as E3 (EIAALEK)3 and K3 (KIAALKE)3 was used to functionalize liposomes

  11. Self-assembling segmented coiled tubing

    Energy Technology Data Exchange (ETDEWEB)

    Raymond, David W.

    2016-09-27

    Self-assembling segmented coiled tubing is a concept that allows the strength of thick-wall rigid pipe, and the flexibility of thin-wall tubing, to be realized in a single design. The primary use is for a drillstring tubular, but it has potential for other applications requiring transmission of mechanical loads (forces and torques) through an initially coiled tubular. The concept uses a spring-loaded spherical `ball-and-socket` type joint to interconnect two or more short, rigid segments of pipe. Use of an optional snap ring allows the joint to be permanently made, in a `self-assembling` manner.

  12. Multiple coil closure of isolated aortopulmonary collateral

    Directory of Open Access Journals (Sweden)

    Padhi Sumanta

    2010-01-01

    Full Text Available A 7-month-old girl was diagnosed to have large aortopulmonary collateral during evaluation for congestive heart failure. There was no other evidence of cardiopulmonary disease. The collateral was successfully closed with multiple coils delivered sequentially. We describe the issues associated during closure of the aortopulmonary collateral in this case. To the best of our knowledge, this is the first reported case of large aortopulmonary collateral presenting with heart failure in an otherwise structurally normal heart that was closed successfully with multiple coils delivered sequentially.

  13. A HTS dipole insert coil constructed

    CERN Document Server

    Ballarino, A; Rey, J M; Stenvall, A; Sorbi, M; Tixador, P

    2013-01-01

    This report is the deliverable report 7.4.1 “A HTS dipole insert coil constructed“. The report has three parts: “Design report for the HTS dipole insert”, “One insert pancake prototype coil constructed with the setup for a high field test”, and “All insert components ordered”. The three report parts show that, although the insert construction will be only completed by end 2013, all elements are present for a successful completion and that, given the important investments done by the participants, there is a full commitment of all of them to finish the project

  14. Comparing acoustic and perceptual voice parameters in female teachers based on voice complaints

    Directory of Open Access Journals (Sweden)

    Maryam Faghani Abukeili

    2014-04-01

    Full Text Available Background and Aim: Teachers are a large group of professional voice users that several risk factors and voice demands causes various voice complaints among them. As the voice is multidimensional, the aim of this study was acoustic and perceptual measurement of teachers’ voice and comparing the findings between two groups with many and few voice complaints.Methods: Sixty female teachers of high school in Sari, north of Iran, were chosen by available sampling to participate in this cross-sectional study. According to a voice complaints questionnaire, 21 subjects located in few voice complaints and 31 in many voice complaints group. After a working day, subjects completed a voice self-assessment questionnaire. Also, teachers’voice were recorded during three tasks including sustained vowels /a/ and /i/, text reading and conversational speech. Acoustic parameters were analyzed by Praat software and 2 speech-language pathalogists performed auditory-perceptual assessment by GRBAS ( Grade, Roughness, Breathiness, Asthenia, Strain scale. Results: Comparing of the voice self-assessment between the two groups demonstrated statistically significant difference (p<0.05; however results of the acoustic and auditory-perceptual measurement did not show significant diffrence.Conclusion: Despite prevalent voice problems in teachers, there are various conditions in terms of complaints and assessments methods. In this study, only a remarkable deviation documented in the client-based assessments in many voice compliants group in comparison with few voice compliants, which would be probably related to different individual’s perception of voice problem between two groups. These results support paying attention to self-assessments in clinical process of voice problems.

  15. The Role of Occupational Voice Demand and Patient-Rated Impairment in Predicting Voice Therapy Adherence.

    Science.gov (United States)

    Ebersole, Barbara; Soni, Resha S; Moran, Kathleen; Lango, Miriam; Devarajan, Karthik; Jamal, Nausheen

    2017-07-11

    Examine the relationship among the severity of patient-perceived voice impairment, perceptual dysphonia severity, occupational voice demand, and voice therapy adherence. Identify clinical predictors of increased risk for therapy nonadherence. A retrospective cohort study of patients presenting with a chief complaint of persistent dysphonia at an interdisciplinary voice center was done. The Voice Handicap Index-10 (VHI-10) and the Voice-Related Quality of Life (V-RQOL) survey scores, clinician rating of dysphonia severity using the Grade score from the Grade, Roughness Breathiness, Asthenia, and Strain scale, occupational voice demand, and patient demographics were tested for associations with therapy adherence, defined as completion of the treatment plan. Classification and Regression Tree (CART) analysis was performed to establish thresholds for nonadherence risk. Of 166 patients evaluated, 111 were recommended for voice therapy. The therapy nonadherence rate was 56%. Occupational voice demand category, VHI-10, and V-RQOL scores were the only factors significantly correlated with therapy adherence (P occupational voice demand are significantly more likely to be nonadherent with therapy than those with high occupational voice demand (P 40 is a significant cutoff point for predicting therapy nonadherence (P Occupational voice demand and patient perception of impairment are significantly and independently correlated with therapy adherence. A VHI-10 score of ≤9 or a V-RQOL score of >40 is a significant cutoff point for predicting nonadherence risk. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  16. 12 tesla test coil. Annual progress report. [Nb/sub 3/Sn

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    The Plasma Fusion Center at MIT has been charged with responsibility for the design, development, fabrication and test operation of a Niobium-3-Tin Superconducting Test Coil. Research is described on DOE's 12 tesla coil demonstration program in which several one-meter diameter superconducting test coils will be inserted and tested in DOE's High Field Test Facility at the Lawrence Livermore Laboratories. The work was initiated at the start of FY 79. FY 79 saw the completion of our Preliminary Design and the initiation of three (3) subcontracts: (1) Westinghouse review of the Preliminary Design, (II) Supercon, Inc. development of a tubular copper matrix, Nb/sub 3/Sn Superconductor and (III) Airco optimization of the LCP-W Nb/sub 3/Sn superconductor for 12T service. In addition, Airco was charged with the production of a 1000 foot length of model 15,000A conductor. Coil winding exercises were initiated at the Everson Electric Company.

  17. High spatial resolution quantitative MR images: an experimental study of dedicated surface coils

    Energy Technology Data Exchange (ETDEWEB)

    Gensanne, D [Laboratoire de Chimie Bioinorganique Medicale, Imagerie therapeutique et diagnostique, JE 2400-CNRS FR 2599, Universite Paul Sabatier, 118, route de Narbonne, 31062 Toulouse Cedex (France); Josse, G [Centre Europeen de Recherche et d' Evaluation sur la Peau et les Epitheliums de Revetement, Institut de Recherche Pierre Fabre, 2, rue Viguerie, BP 3071 31025 Toulouse Cedex 3 (France); Lagarde, J M [Centre Europeen de Recherche et d' Evaluation sur la Peau et les Epitheliums de Revetement, Institut de Recherche Pierre Fabre, 2, rue Viguerie, BP 3071 31025 Toulouse Cedex 3 (France); Vincensini, D [Laboratoire de Chimie Bioinorganique Medicale, Imagerie therapeutique et diagnostique, JE 2400-CNRS FR 2599, Universite Paul Sabatier, 118, route de Narbonne, 31062 Toulouse Cedex (France)

    2006-06-07

    Measuring spin-spin relaxation times (T{sub 2}) by quantitative MR imaging represents a potentially efficient tool to evaluate the physicochemical properties of various media. However, noise in MR images is responsible for uncertainties in the determination of T{sub 2} relaxation times, which limits the accuracy of parametric tissue analysis. The required signal-to-noise ratio (SNR) depends on the T{sub 2} relaxation behaviour specific to each tissue. Thus, we have previously shown that keeping the uncertainty in T{sub 2} measurements within a limit of 10% implies that SNR values be greater than 100 and 300 for mono- and biexponential T{sub 2} relaxation behaviours, respectively. Noise reduction can be obtained either by increasing the voxel size (i.e., at the expense of spatial resolution) or by using high sensitivity dedicated surface coils (which allows us to increase SNR without deteriorating spatial resolution in an excessive manner). However, surface coil sensitivity is heterogeneous, i.e., it- and hence SNR-decreases with increasing depth, and the more so as the coil radius is smaller. The use of surface coils is therefore limited to the analysis of superficial structure such as the hypodermic tissue analysed here. The aim of this work was to determine the maximum limits of spatial resolution and depth compatible with reliable in vivo T{sub 2} quantitative MR images using dedicated surface coils available on various clinical MR scanners. The average thickness of adipose tissue is around 15 mm, and the results obtained have shown that obtaining reliable biexponential relaxation analysis requires a minimum achievable voxel size of 13 mm{sup 3} for a conventional volume birdcage coil and only of 1.7 mm{sup 3} for the smallest available surface coil (23 mm in diameter). Further improvement in spatial resolution allowing us to detect low details in MR images without deteriorating parametric T{sub 2} images can be obtained by image filtering. By using the non

  18. Tx/Rx Head Coil Induces Less RF Transmit-Related Heating than Body Coil in Conductive Metallic Objects Outside the Active Area of the Head Coil.

    Science.gov (United States)

    Nagy, Zoltan; Oliver-Taylor, Aaron; Kuehne, Andre; Goluch, Sigrun; Weiskopf, Nikolaus

    2017-01-01

    The transmit-receive (Tx/Rx) birdcage head coil is often used for excitation instead of the body coil because of the presumably lower risk of heating in and around conductive implants. However, this common practice has not been systematically tested. To investigate whether the Tx/Rx birdcage head coil produces less heating than the body coil when scanning individuals with implants, we used a 3T clinical scanner and made temperature measurements around a straight 15 cm conductor using either the Tx/Rx body or the head coil for excitation. Additionally, the transmitted fields of a Tx/Rx head coil were measured both in air and in gel using a resonant and a non-resonant B field probes as well as a non-resonant E field probe. Simulations using a finite-difference time domain solver were compared with the experimental findings. When the body coil was used for excitation, we observed heating around the 15 cm wire at various anatomical locations (both within and outside of the active volume of the head coil). Outside its active area, no such heating was observed while using the Tx/Rx head coil for excitation. The E and B fields of the Tx/Rx birdcage head coil extended well-beyond the physical dimensions of the coil. In air, the fields were monotonically decreasing, while in gel they were more complex with local maxima at the end of the ASTM phantom. These experimental findings were line with the simulations. While caution must always be exercised when scanning individuals with metallic implants, these findings support the use of the Tx/Rx birdcage head coil in place of the body coil at 3T in order to reduce the risk of heating in and around conductive implants that are remote from the head coil.

  19. Tx/Rx Head Coil Induces Less RF Transmit-Related Heating than Body Coil in Conductive Metallic Objects Outside the Active Area of the Head Coil

    Science.gov (United States)

    Nagy, Zoltan; Oliver-Taylor, Aaron; Kuehne, Andre; Goluch, Sigrun; Weiskopf, Nikolaus

    2017-01-01

    The transmit–receive (Tx/Rx) birdcage head coil is often used for excitation instead of the body coil because of the presumably lower risk of heating in and around conductive implants. However, this common practice has not been systematically tested. To investigate whether the Tx/Rx birdcage head coil produces less heating than the body coil when scanning individuals with implants, we used a 3T clinical scanner and made temperature measurements around a straight 15 cm conductor using either the Tx/Rx body or the head coil for excitation. Additionally, the transmitted fields of a Tx/Rx head coil were measured both in air and in gel using a resonant and a non-resonant B field probes as well as a non-resonant E field probe. Simulations using a finite-difference time domain solver were compared with the experimental findings. When the body coil was used for excitation, we observed heating around the 15 cm wire at various anatomical locations (both within and outside of the active volume of the head coil). Outside its active area, no such heating was observed while using the Tx/Rx head coil for excitation. The E and B fields of the Tx/Rx birdcage head coil extended well-beyond the physical dimensions of the coil. In air, the fields were monotonically decreasing, while in gel they were more complex with local maxima at the end of the ASTM phantom. These experimental findings were line with the simulations. While caution must always be exercised when scanning individuals with metallic implants, these findings support the use of the Tx/Rx birdcage head coil in place of the body coil at 3T in order to reduce the risk of heating in and around conductive implants that are remote from the head coil.

  20. Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils

    Science.gov (United States)

    Ahrentorp, Fredrik; Blomgren, Jakob; Jonasson, Christian; Sarwe, Anna; Sepehri, Sobhan; Eriksson, Emil; Kalaboukhov, Alexei; Jesorka, Aldo; Winkler, Dag; Schneiderman, Justin F.; Nilsson, Mats; Albert, Jan; de la Torre, Teresa Zardán Gómez; Strømme, Maria; Johansson, Christer

    2017-04-01

    We use functionalized iron oxide magnetic multi-core particles of 100 nm in size (hydrodynamic particle diameter) and AC susceptometry (ACS) methods to measure the binding reactions between the magnetic nanoparticles (MNPs) and bio-analyte products produced from DNA segments using the rolling circle amplification (RCA) method. We use sensitive induction detection techniques in order to measure the ACS response. The DNA is amplified via RCA to generate RCA coils with a specific size that is dependent on the amplification time. After about 75 min of amplification we obtain an average RCA coil diameter of about 1 μm. We determine a theoretical limit of detection (LOD) in the range of 11 attomole (corresponding to an analyte concentration of 55 fM for a sample volume of 200 μL) from the ACS dynamic response after the MNPs have bound to the RCA coils and the measured ACS readout noise. We also discuss further possible improvements of the LOD.

  1. Perturbation Measures of Voice: A Comparative Study between Multi-Dimensional Voice Program and Praat

    National Research Council Canada - National Science Library

    Maryn, Youri; Corthals, Paul; De Bodt, Marc; Van Cauwenberge, Paul; Deliyski, Dimitar

    2009-01-01

    .... In the present study, perturbation measures provided by two computer systems (a purpose-built professional voice analysis apparatus and a personal computer-based system for acoustic voice assessment...

  2. [The smokers voice self assessment based on Voice Handicap Index (VHI)].

    Science.gov (United States)

    Wiskirska-Woźnica, Bozena; Wojnowski, Waldemar

    2009-01-01

    Complex voice assessment due to European Laryngeal Society proposals (2000) contains voice self estimation based on the Polish version of the Voice Handicap Index (VHI). This study focuses on the relation between voice handicap and smoking in dysphonic patients, who are using voice professionally. Thirty outpatient (25 female and 5 male, aged 40 to 55 years) voice department attendees suffering from professional dysphonia took part in this study. All patients after phoniatric examination completed the Polish version of the Voice Handicap Index (VHI). The questions concern functional, emotional and physical complains due to dysphonia. Most of smokers did not complain of dysphonia related problems comparing to non smokers. Even the scores of functional and emotional scales of VHI in smokers shown better results (less handicap) than in nonsmokers. Smoking does not affect patients handicap due to dysphonia measured in the Voice Handicap Index.

  3. Qos and Voice Over IP

    Directory of Open Access Journals (Sweden)

    Adrian GHENCEA

    Full Text Available As Voice over Internet Protocol (VoIP technology matures, companies are increasingly adopting it to cut costs, improve efficiency and enhance customer service. Using the Internet as an existing network for integrating data and telecom systems through intelligent VoIP, a range of benefits results: lower long distance costs, cost cuts in cabling processes and more flexible telephony management. However, as voice over IP services grow in popularity, major threats arise: this rapid growth leads to traffic congestion, security is jeopardizedand the poor quality of calls affects communication. The objective of this article is to present all the elements that can affect voicequality in a VoIP network and to provide methods for solving them. A detailed analysis to minimize the impact of implementation of QoS will be made, and at the end solutions to management strategies will be proposed.

  4. Effect of Religiosity on Voice.

    Science.gov (United States)

    Hamdan, Abdul-Latif; Khneisser, Gebran; Dowli, Alex; Ziade, Georges; Tamim, Hani

    2017-04-01

    The aim of this study was to examine the relationship between religiosity and phonatory behavior. A total of 186 participants participated in a survey that included four sections: demographic data, extent of religiosity, history of dysphonia, phonatory behavior and laryngeal manipulation, in addition to the Voice Handicap Index (VHI-10). There was no significant association between the prevalence of phonatory symptoms and any of the religiosity questions. There was no significant association between phonatory behavior, history of laryngeal manipulation and any of the religiosity questions. There was also no significant association between the score of the Voice Handicap Index and any of the five religiosity questions. There is no association between religiosity and prevalence of phonatory disturbances, phonotraumatic behavior and/or history of laryngeal manipulation.

  5. Optimization of a conduction-cooled LTS pulse coil

    Energy Technology Data Exchange (ETDEWEB)

    Kawagoe, A. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan)]. E-mail: kawagoe@eee.kagoshima-u.ac.jp; Yamamuro, H. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan); Sumiyoshi, F. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan); Mito, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Chikaraishi, H. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Hemmi, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Baba, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Yokota, M. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Morita, Y. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Ogawa, H. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Abe, R. [Shibuya Kogyo Co., Ltd., Kanazawa, Ishikawa 920-0054 (Japan); Okumura, K. [Technova Inc., Chiyoda-ku, Tokyo 100-0011 (Japan); Iwakuma, M. [Kyushu University, Higashi-ku, Fukuoka 812-8581 (Japan)

    2006-11-15

    The output limit of the available power of a prototype conduction-cooled low temperature superconducting (LTS) pulse coil is clarified for the optimization of the coil. The winding conductor of this coil is a NbTi/Cu Rutherford cable, which is extruded with aluminum. Dyneema[reg] fiber reinforced plastics (DFRP) and Litz wires are used as the spacers of this coil. A prototype coil with a stored energy of 100 kJ was successfully fabricated and tested, and the coil performed excellently. In this paper, the stability margin of this coil is clarified by thermal analysis, using a two-dimensional finite element method, taking into account the effects of both types of spacers, DFRP and Litz wires. Additionally, the maximum output power of the coil is estimated at about three times the rated output.

  6. Modular Coils and Plasma Configurations for Quasi-axisymmetric Stellarators

    Energy Technology Data Exchange (ETDEWEB)

    L.P. Ku and A.H. Boozer

    2010-09-10

    Characteristics of modular coils for quasi-axisymmetric stellarators that are related to the plasma aspect ratio, number of field periods and rotational transform have been examined systematically. It is observed that, for a given plasma aspect ratio, the coil complexity tends to increase with the increased number of field periods. For a given number of field periods, the toroidal excursion of coil winding is reduced as the plasma aspect ratio is increased. It is also clear that the larger the coil-plasma separation is, the more complex the coils become. It is further demonstrated that it is possible to use other types of coils to complement modular coils to improve both the physics and the modular coil characteristics.

  7. Thermophoresis of polymers: nondraining vs draining coil.

    Science.gov (United States)

    Morozov, Konstantin I; Köhler, Werner

    2014-06-10

    Present theories for the thermophoretic mobility of polymers in dilute solution without long-ranged electrostatic interaction are based on a draining coil model with short-ranged segment-solvent interaction. We show that the characteristic thermophoretic interaction decays as r(-2) with the distance from the chain segment, which is of much longer range than the underlying rapidly decaying binary van der Waals interaction (∝ r(-6)). As a consequence, thermophoresis on the monomer level is governed by volume forces, resulting in hydrodynamic coupling between the chain segments. The inner parts of the nondraining coil do not actively participate in thermophoresis. The flow lines penetrate only into a thin surface layer of the coil and cause tangential stresses along the surface of the entire coil, not the individual segments. This model is motivated by recent experimental findings for thermoresponsive polymers and core-shell particles, and it explains the well-known molar mass independent thermophoretic mobility of polymers in dilute solution.

  8. Coil in bottom part of splitter magnet

    CERN Multimedia

    1976-01-01

    Radiation-resistant coil being bedded into the bottom part of a splitter magnet. This very particular magnet split the beam into 3 branches, for 3 target stations in the West-Area. See Annual Report 1975, p.176, Figs.14 and 15.

  9. Stellarator Coil Design and Plasma Sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Long-Poe Ku and Allen H. Boozer

    2010-11-03

    The rich information contained in the plasma response to external magnetic perturbations can be used to help design stellarator coils more effectively. We demonstrate the feasibility by first devel- oping a simple, direct method to study perturbations in stellarators that do not break stellarator symmetry and periodicity. The method applies a small perturbation to the plasma boundary and evaluates the resulting perturbed free-boundary equilibrium to build up a sensitivity matrix for the important physics attributes of the underlying configuration. Using this sensitivity information, design methods for better stellarator coils are then developed. The procedure and a proof-of-principle application are given that (1) determine the spatial distributions of external normal magnetic field at the location of the unperturbed plasma boundary to which the plasma properties are most sen- sitive, (2) determine the distributions of external normal magnetic field that can be produced most efficiently by distant coils, (3) choose the ratios of the magnitudes of the the efficiently produced magnetic distributions so the sensitive plasma properties can be controlled. Using these methods, sets of modular coils are found for the National Compact Stellarator Experiment (NCSX) that are either smoother or can be located much farther from the plasma boundary than those of the present design.

  10. Penile hair coil strangulation of the child

    African Journals Online (AJOL)

    shanker

    We report the case of a child with a delayed presentation of penile strangulation with a coil of hair that resulted in a complete ... erection in some of them and with autoerotic intentions in others. ... in children with underlying urological problems.

  11. Voice disorders in mucosal leishmaniasis.

    Directory of Open Access Journals (Sweden)

    Ana Cristina Nunes Ruas

    Full Text Available INTRODUCTION: Leishmaniasis is considered as one of the six most important infectious diseases because of its high detection coefficient and ability to produce deformities. In most cases, mucosal leishmaniasis (ML occurs as a consequence of cutaneous leishmaniasis. If left untreated, mucosal lesions can leave sequelae, interfering in the swallowing, breathing, voice and speech processes and requiring rehabilitation. OBJECTIVE: To describe the anatomical characteristics and voice quality of ML patients. MATERIALS AND METHODS: A descriptive transversal study was conducted in a cohort of ML patients treated at the Laboratory for Leishmaniasis Surveillance of the Evandro Chagas National Institute of Infectious Diseases-Fiocruz, between 2010 and 2013. The patients were submitted to otorhinolaryngologic clinical examination by endoscopy of the upper airways and digestive tract and to speech-language assessment through directed anamnesis, auditory perception, phonation times and vocal acoustic analysis. The variables of interest were epidemiologic (sex and age and clinic (lesion location, associated symptoms and voice quality. RESULTS: 26 patients under ML treatment and monitored by speech therapists were studied. 21 (81% were male and five (19% female, with ages ranging from 15 to 78 years (54.5+15.0 years. The lesions were distributed in the following structures 88.5% nasal, 38.5% oral, 34.6% pharyngeal and 19.2% laryngeal, with some patients presenting lesions in more than one anatomic site. The main complaint was nasal obstruction (73.1%, followed by dysphonia (38.5%, odynophagia (30.8% and dysphagia (26.9%. 23 patients (84.6% presented voice quality perturbations. Dysphonia was significantly associated to lesions in the larynx, pharynx and oral cavity. CONCLUSION: We observed that vocal quality perturbations are frequent in patients with mucosal leishmaniasis, even without laryngeal lesions; they are probably associated to disorders of some

  12. WHEEL CHAIR USING VOICE RECOGNITION

    OpenAIRE

    Manish Kumar Yadav*; Rajat Kumar; Santosh Yadav; Ravindra Prajapati; Prof. Kshirsagar

    2016-01-01

    The wide spread prevalence of lost limbs and sensing system is of major concern in present day due to wars, accident, age and health problems. This Omni-directional wheelchair was designed for the less able elderly to move more flexibly in narrow spaces, such as elevators or small aisle. The wheelchair is developed to help disabled patients by using speech recognition system to control the movement of wheelchair in different directions by using voice commands and also the simple movement of t...

  13. English Spoken Language & Voice Quality

    OpenAIRE

    Folsberg, Jens; Nielsen, Charlotte; Brusokaite, Giedre; Beinkamp, Line; Bach Jensen, Niels; Aalbæk Jensen, Sandra

    2013-01-01

    This project investigates the way language and accents are depicted in animated features and how linguistic stereotypes can be used in the process of character construction. In order to look into that, examples from four movies, produced by two studios, have been selected; the American Disney studios being represented by The Lion King (1994) and Up (2009), and the Japanese Studio Ghibli being represented by Ponyo (2008) and Howl's Moving Castle (2004). Voice qualities and specific accents ...

  14. Tracheostomy cannulas and voice prosthesis

    OpenAIRE

    2011-01-01

    Cannulas and voice prostheses are mechanical aids for patients who had to undergo tracheotomy or laryngectomy for different reasons. For better understanding of the function of those artificial devices, first the indications and particularities of the previous surgical intervention are described in the context of this review. Despite the established procedure of percutaneous dilatation tracheotomy e.g. in intensive care units, the application of epithelised tracheostomas has its own position,...

  15. The voice of the voiceless

    Directory of Open Access Journals (Sweden)

    Carlos Morales

    2014-12-01

    Full Text Available Women’s voice, these are stories of a group of women and their partners who lived part of a particular historical period agriculture during the twentieth century, the hacienda. The present work attempts to reflect their everyday life, reinterpreted from nowadays as a reflection of collective memory, in the big farms where they grew by putting in scene their roles in juxtaposition to the roles of male tradition.

  16. Microhole High-Pressure Jet Drill for Coiled Tubing

    Energy Technology Data Exchange (ETDEWEB)

    Ken Theimer; Jack Kolle

    2007-06-30

    Tempress Small Mechanically-Assisted High-Pressure Waterjet Drilling Tool project centered on the development of a downhole intensifier (DHI) to boost the hydraulic pressure available from conventional coiled tubing to the level required for high-pressure jet erosion of rock. We reviewed two techniques for implementing this technology (1) pure high-pressure jet drilling and (2) mechanically-assisted jet drilling. Due to the difficulties associated with modifying a downhole motor for mechanically-assisted jet drilling, it was determined that the pure high-pressure jet drilling tool was the best candidate for development and commercialization. It was also determined that this tool needs to run on commingled nitrogen and water to provide adequate downhole differential pressure and to facilitate controlled pressure drilling and descaling applications in low pressure wells. The resulting Microhole jet drilling bottomhole assembly (BHA) drills a 3.625-inch diameter hole with 2-inch coil tubing. The BHA consists of a self-rotating multi-nozzle drilling head, a high-pressure rotary seal/bearing section, an intensifier and a gas separator. Commingled nitrogen and water are separated into two streams in the gas separator. The water stream is pressurized to 3 times the inlet pressure by the downhole intensifier and discharged through nozzles in the drilling head. The energy in the gas-rich stream is used to power the intensifier. Gas-rich exhaust from the intensifier is conducted to the nozzle head where it is used to shroud the jets, increasing their effective range. The prototype BHA was tested at operational pressures and flows in a test chamber and on the end of conventional coiled tubing in a test well. During instrumented runs at downhole conditions, the BHA developed downhole differential pressures of 74 MPa (11,000 psi, median) and 90 MPa (13,000 psi, peaks). The median output differential pressure was nearly 3 times the input differential pressure available from the

  17. Voice congruency facilitates word recognition.

    Directory of Open Access Journals (Sweden)

    Sandra Campeanu

    Full Text Available Behavioral studies of spoken word memory have shown that context congruency facilitates both word and source recognition, though the level at which context exerts its influence remains equivocal. We measured event-related potentials (ERPs while participants performed both types of recognition task with words spoken in four voices. Two voice parameters (i.e., gender and accent varied between speakers, with the possibility that none, one or two of these parameters was congruent between study and test. Results indicated that reinstating the study voice at test facilitated both word and source recognition, compared to similar or no context congruency at test. Behavioral effects were paralleled by two ERP modulations. First, in the word recognition test, the left parietal old/new effect showed a positive deflection reflective of context congruency between study and test words. Namely, the same speaker condition provided the most positive deflection of all correctly identified old words. In the source recognition test, a right frontal positivity was found for the same speaker condition compared to the different speaker conditions, regardless of response success. Taken together, the results of this study suggest that the benefit of context congruency is reflected behaviorally and in ERP modulations traditionally associated with recognition memory.

  18. Comparison of an Electromagnetic Energy Harvester Performance using Wound Coil Wire and PCB Coil

    Science.gov (United States)

    Resali, MSM; Salleh, H.

    2016-03-01

    This paper presents the performance of two types of electromagnetic energy harvester, one using manually wound coil wire (EH-EC) and the other one using printed circuit board (PCB) coil (EH-EP). The objective of the study is to measure the corresponding output voltage and power by varying the number of coils and the position of the magnet. The experiment was conducted at a fix 50 Hz of frequency and at 0.25g of acceleration. The EH-EP was found to be more effective than the 350 turns of the wound coil wire, with maximum power of 26 μW. Overall, the performance of the EH-EC showed better result with maximum power of 125 μW for 1050 turns when compared to the EH-EP.

  19. Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

    Energy Technology Data Exchange (ETDEWEB)

    McNamara, Case; Zinkernagel, Annelies S.; Macheboeuf, Pauline; Cunningham, Madeleine W.; Nizet, Victor; Ghosh, Partho (UO-HSC); (UCSD)

    2008-07-21

    Antigenically variable M proteins are major virulence factors and immunogens of the human pathogen group A Streptococcus (GAS). Here, we report the -3 angstrom resolution structure of a GAS M1 fragment containing the regions responsible for eliciting type-specific, protective immunity and for binding fibrinogen, which promotes M1 proinflammatory and antiphagocytic functions. The structure revealed substantial irregularities and instabilities throughout the coiled coil of the M1 fragment. Similar structural irregularities occur in myosin and tropomyosin, explaining the patterns of cross-reactivity seen in autoimmune sequelae of GAS infection. Sequence idealization of a large segment of the M1 coiled coil enhanced stability but diminished fibrinogen binding, proinflammatory effects, and antibody cross-reactivity, whereas it left protective immunogenicity undiminished. Idealized M proteins appear to have promise as vaccine immunogens.

  20. Voices in (and around the Museum: Introduction

    Directory of Open Access Journals (Sweden)

    Ruth Holt

    2012-08-01

    Full Text Available The voice already plays an important role in contemporary art. This introductory paper summarises a series of four sessions in which speakers explored the place of the voice in the museum context. It became clear that the voice not only offered richness in interpretation of and response to other museum artefacts but was itself an artefact meriting conservation  and interpretation.

  1. Multiple-Coil, Pulse-Induction Metal Detector

    Science.gov (United States)

    Lesky, Edward S.; Reid, Alan M.; Bushong, Wilton E.; Dickey, Duane P.

    1988-01-01

    Multiple-head, pulse-induction metal detector scans area of 72 feet squared with combination of eight detector heads, each 3 ft. square. Head includes large primary coil inducing current in smaller secondary coils. Array of eight heads enables searcher to cover large area quickly. Pulses applied to primary coil, induced in secondary coils measured to determine whether metal present within range of detector head. Detector designed for recovery of Space Shuttle debris.

  2. Design and Testing of Coils for Pulsed Electromagnetic Forming

    OpenAIRE

    Golovashchenko, S.; Bessonov, N.; Davies, R

    2006-01-01

    Coil design influences the distribution of electromagnetic forces applied to both the blank and the coil. The required energy of the process is usually defined by deformation of the blank. However, the discharge also results in a significant amount of heat being generated and accumulating in the coil. Therefore, EMF process design involves working with three different problems: 1) propagation of an electromagnetic field through the coil-blank system and generation of pulsed electromagnetic pr...

  3. GBNV encoded movement protein (NSm) remodels ER network via C-terminal coiled coil domain

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Pratibha; Savithri, H.S., E-mail: bchss@biochem.iisc.ernet.in

    2015-08-15

    Plant viruses exploit the host machinery for targeting the viral genome–movement protein complex to plasmodesmata (PD). The mechanism by which the non-structural protein m (NSm) of Groundnut bud necrosis virus (GBNV) is targeted to PD was investigated using Agrobacterium mediated transient expression of NSm and its fusion proteins in Nicotiana benthamiana. GFP:NSm formed punctuate structures that colocalized with mCherry:plasmodesmata localized protein 1a (PDLP 1a) confirming that GBNV NSm localizes to PD. Unlike in other movement proteins, the C-terminal coiled coil domain of GBNV NSm was shown to be involved in the localization of NSm to PD, as deletion of this domain resulted in the cytoplasmic localization of NSm. Treatment with Brefeldin A demonstrated the role of ER in targeting GFP NSm to PD. Furthermore, mCherry:NSm co-localized with ER–GFP (endoplasmic reticulum targeting peptide (HDEL peptide fused with GFP). Co-expression of NSm with ER–GFP showed that the ER-network was transformed into vesicles indicating that NSm interacts with ER and remodels it. Mutations in the conserved hydrophobic region of NSm (residues 130–138) did not abolish the formation of vesicles. Additionally, the conserved prolines at positions 140 and 142 were found to be essential for targeting the vesicles to the cell membrane. Further, systematic deletion of amino acid residues from N- and C-terminus demonstrated that N-terminal 203 amino acids are dispensable for the vesicle formation. On the other hand, the C-terminal coiled coil domain when expressed alone could also form vesicles. These results suggest that GBNV NSm remodels the ER network by forming vesicles via its interaction through the C-terminal coiled coil domain. Interestingly, NSm interacts with NP in vitro and coexpression of these two proteins in planta resulted in the relocalization of NP to PD and this relocalization was abolished when the N-terminal unfolded region of NSm was deleted. Thus, the NSm

  4. Compressing DNA sequence databases with coil

    Directory of Open Access Journals (Sweden)

    Hendy Michael D

    2008-05-01

    Full Text Available Abstract Background Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems. Currently, sequence data is usually kept in large "flat files," which are then compressed using standard Lempel-Ziv (gzip compression – an approach which rarely achieves good compression ratios. While much research has been done on compressing individual DNA sequences, surprisingly little has focused on the compression of entire databases of such sequences. In this study we introduce the sequence database compression software coil. Results We have designed and implemented a portable software package, coil, for compressing and decompressing DNA sequence databases based on the idea of edit-tree coding. coil is geared towards achieving high compression ratios at the expense of execution time and memory usage during compression – the compression time represents a "one-off investment" whose cost is quickly amortised if the resulting compressed file is transmitted many times. Decompression requires little memory and is extremely fast. We demonstrate a 5% improvement in compression ratio over state-of-the-art general-purpose compression tools for a large GenBank database file containing Expressed Sequence Tag (EST data. Finally, coil can efficiently encode incremental additions to a sequence database. Conclusion coil presents a compelling alternative to conventional compression of flat files for the storage and distribution of DNA sequence databases having a narrow distribution of sequence lengths, such as EST data. Increasing compression levels for databases having a wide distribution of sequence lengths is a direction for future work.

  5. Speak Up! But don't strain your voice

    Science.gov (United States)

    ... Disorders Speak Up! But don't strain your voice Past Issues / Fall 2008 Table of Contents For ... Javascript on. A clinical trial at the NIDCD Voice Center gave Sherdina Jones tools to limit voice ...

  6. Familiarity and Voice Representation: From Acoustic-Based Representation to Voice Averages

    Directory of Open Access Journals (Sweden)

    Maureen Fontaine

    2017-07-01

    Full Text Available The ability to recognize an individual from their voice is a widespread ability with a long evolutionary history. Yet, the perceptual representation of familiar voices is ill-defined. In two experiments, we explored the neuropsychological processes involved in the perception of voice identity. We specifically explored the hypothesis that familiar voices (trained-to-familiar (Experiment 1, and famous voices (Experiment 2 are represented as a whole complex pattern, well approximated by the average of multiple utterances produced by a single speaker. In experiment 1, participants learned three voices over several sessions, and performed a three-alternative forced-choice identification task on original voice samples and several “speaker averages,” created by morphing across varying numbers of different vowels (e.g., [a] and [i] produced by the same speaker. In experiment 2, the same participants performed the same task on voice samples produced by familiar speakers. The two experiments showed that for famous voices, but not for trained-to-familiar voices, identification performance increased and response times decreased as a function of the number of utterances in the averages. This study sheds light on the perceptual representation of familiar voices, and demonstrates the power of average in recognizing familiar voices. The speaker average captures the unique characteristics of a speaker, and thus retains the information essential for recognition; it acts as a prototype of the speaker.

  7. Speaking up in groups: a cross-level study of group voice climate and voice.

    Science.gov (United States)

    Morrison, Elizabeth Wolfe; Wheeler-Smith, Sara L; Kamdar, Dishan

    2011-01-01

    Despite a growing body of research on employee voice—defined as the discretionary communication of ideas, suggestions, or opinions intended to improve organizational or unit functioning—the effects of shared or collective-level cognitions have received scant attention. There has also been relatively little research on voice within work groups. Our goal in this study was to address these important gaps by focusing on the effects of group-level beliefs about voice (i.e., group voice climate) on individual voice behavior within work groups. We conducted a cross-level investigation of voice behavior within 42 groups of engineers from a large chemical company. Consistent with our hypotheses, group voice climate was highly predictive of voice and explained variance beyond the effects of individual-level identification and satisfaction, and procedural justice climate. Also consistent with predictions, the effect of identification on voice was stronger in groups with favorable voice climates. These findings provide evidence that voice is shaped not just by individual attitudes and perceptions of the work context, as past research has shown, but also by group-level beliefs. The results also highlight the importance of broadening our conceptual models of voice to include shared cognitions and of conducting additional cross-level research on voice.

  8. Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis.

    Science.gov (United States)

    Dixon, Andrew S; Miller, Geoffrey D; Bruno, Benjamin J; Constance, Jonathan E; Woessner, David W; Fidler, Trevor P; Robertson, James C; Cheatham, Thomas E; Lim, Carol S

    2012-01-01

    The oncoprotein Bcr-Abl drives aberrant downstream activity through trans-autophosphorylation of homo-oligomers in chronic myelogenous leukemia (CML).(1, 2) The formation of Bcr-Abl oligomers is achieved through the coiled-coil domain at the N-terminus of Bcr.(3, 4) We have previously reported a modified version of this coiled-coil domain, CCmut2, which exhibits disruption of Bcr-Abl oligomeric complexes and results in decreased proliferation of CML cells and induction of apoptosis.(5) A major contributing factor to these enhanced capabilities is the destabilization of the CCmut2 homodimers, increasing the availability to interact with and inhibit Bcr-Abl. Here, we included an additional mutation (K39E) that could in turn further destabilize the mutant homodimer. Incorporation of this modification into CCmut2 (C38A, S41R, L45D, E48R, Q60E) generated what we termed CCmut3, and resulted in further improvements in the binding properties with the wild-type coiled-coil domain representative of Bcr-Abl [corrected]. A separate construct containing one revert mutation, CCmut4, did not demonstrate improved oligomeric properties and indicated the importance of the L45D mutation. CCmut3 demonstrated improved oligomerization via a two-hybrid assay as well as through colocalization studies, in addition to showing similar biologic activity as CCmut2. The improved binding between CCmut3 and the Bcr-Abl coiled-coil may be used to redirect Bcr-Abl to alternative subcellular locations with interesting therapeutic implications.

  9. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

    Directory of Open Access Journals (Sweden)

    Nora Céspedes

    Full Text Available Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Plasmodium falciparum were identified in the P. vivax genome. The peptides identified in silico were chemically synthesized; circular dichroism studies indicated partial or high α-helical content. Antigenicity was evaluated using human sera samples from malaria-endemic areas of Colombia and Papua New Guinea. Eight of these fragments were selected and used to assess immunogenicity in BALB/c mice. ELISA assays indicated strong reactivity of serum samples from individuals residing in malaria-endemic regions and sera of immunized mice, with the α-helical coiled coil structures. In addition, ex vivo production of IFN-γ by murine mononuclear cells confirmed the immunogenicity of these structures and the presence of T-cell epitopes in the peptide sequences. Moreover, sera of mice immunized with four of the eight antigens recognized native proteins on blood-stage P. vivax parasites, and antigenic cross-reactivity with three of the peptides was observed when reacted with both the P. falciparum orthologous fragments and whole parasites. Results here point to the α-helical coiled coil peptides as possible P. vivax malaria vaccine candidates as were observed for P. falciparum. Fragments selected here warrant further study in humans and non-human primate models to assess their protective efficacy as single components or assembled as hybrid linear epitopes.

  10. Coiled-coil forming peptides for the induction of silver nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Božič Abram, Sabina [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Graduate School of Biomedicine, University of Ljubljana, Ljubljana 1000 (Slovenia); Aupič, Jana [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Doctoral Programme in Chemical Sciences, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana 1000 (Slovenia); Dražić, Goran [Laboratory for Materials Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Gradišar, Helena [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia); Jerala, Roman, E-mail: roman.jerala@ki.si [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia)

    2016-04-08

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  11. Data-driven prediction and design of bZIP coiled-coil interactions.

    Science.gov (United States)

    Potapov, Vladimir; Kaplan, Jenifer B; Keating, Amy E

    2015-02-01

    Selective dimerization of the basic-region leucine-zipper (bZIP) transcription factors presents a vivid example of how a high degree of interaction specificity can be achieved within a family of structurally similar proteins. The coiled-coil motif that mediates homo- or hetero-dimerization of the bZIP proteins has been intensively studied, and a variety of methods have been proposed to predict these interactions from sequence data. In this work, we used a large quantitative set of 4,549 bZIP coiled-coil interactions to develop a predictive model that exploits knowledge of structurally conserved residue-residue interactions in the coiled-coil motif. Our model, which expresses interaction energies as a sum of interpretable residue-pair and triplet terms, achieves a correlation with experimental binding free energies of R = 0.68 and significantly out-performs other scoring functions. To use our model in protein design applications, we devised a strategy in which synthetic peptides are built by assembling 7-residue native-protein heptad modules into new combinations. An integer linear program was used to find the optimal combination of heptads to bind selectively to a target human bZIP coiled coil, but not to target paralogs. Using this approach, we designed peptides to interact with the bZIP domains from human JUN, XBP1, ATF4 and ATF5. Testing more than 132 candidate protein complexes using a fluorescence resonance energy transfer assay confirmed the formation of tight and selective heterodimers between the designed peptides and their targets. This approach can be used to make inhibitors of native proteins, or to develop novel peptides for applications in synthetic biology or nanotechnology.

  12. The electrolarynx: voice restoration after total laryngectomy.

    Science.gov (United States)

    Kaye, Rachel; Tang, Christopher G; Sinclair, Catherine F

    2017-01-01

    The ability to speak and communicate with one's voice is a unique human characteristic and is fundamental to many activities of daily living, such as talking on the phone and speaking to loved ones. When the larynx is removed during a total laryngectomy (TL), loss of voice can lead to a devastating decrease in a patient's quality of life, and precipitate significant frustration over their inability to communicate with others effectively. Over the past 50 years there have been many advances in techniques of voice restoration after TL. Currently, there are three main methods of voice restoration: the electrolarynx, esophageal speech, and tracheoesophageal speech through a tracheoesophageal puncture (TEP) with voice prosthesis. Although TEP voice is the current gold standard for vocal rehabilitation, a significant minority of patients cannot use or obtain TEP speech for various reasons. As such, the electrolarynx is a viable and useful alternative for these patients. This article will focus on voice restoration using an electrolarynx with the following objectives: 1) To provide an understanding of the importance of voice restoration after total laryngectomy. 2) To discuss how the electrolarynx may be used to restore voice following total laryngectomy. 3) To outline some of the current electrolarynx devices available, including their mechanism of action and limitations. 4) To compare pros and cons of electrolaryngeal speech to TEP and esophageal speech.

  13. The Performing Voice of the Audiobook

    DEFF Research Database (Denmark)

    Pedersen, Birgitte Stougaard; Have, Iben

    2014-01-01

    will be based on a reception aesthetic and phenomenological approach, the latter as presented by Don Ihde in his book Listening and Voice. Phenomenologies of Sound , and my analytical sketches will be related to theoretical statements concerning the understanding of voice and media (Cavarero, Dolar, La......Belle, Neumark). Finally, the article will discuss the specific artistic combination and our auditory experience of mediated human voices and sculpturally projected faces in an art museum context under the general conditions of the societal panophonia of disembodied and mediated voices, as promoted by Steven...

  14. Methods of Translating the English passive voice

    Institute of Scientific and Technical Information of China (English)

    张李丽

    2009-01-01

    @@ 一、Comparisons between Voices in English and Chinese In English as in many other languages,the passive voice is the form of a transitive verb whose grammatical sabjOct serves as the patient,receiving the action of the verb.The passive voice is typically contrasted with the active voice,which is the form of a transitive verb whose subject serves as the agent,performing the action of the verb.The subject of a verb in the passive voice corresponds to the object of the same verb in the active voice.English's passive voice is periphrastic;that is,it does not have a one-word form.Rather,it is formed using a form of the auxiliary verb be together with a verb's past participle.The passive voice is widely used in English when it is unnecessary,undesirable,or impossible to ilame the agent of an action,or when the passive voice is needed to link the text better.

  15. Prevalence of voice disorders among future teachers.

    Science.gov (United States)

    Simberg, S; Laine, A; Sala, E; Rönnemaa, A M

    2000-06-01

    An epidemiological study was conducted in order to find out the prevalence of voice disorders among students studying to be teachers. Vocal symptoms were inquired of 226 students. Their voices were assessed perceptually by a speech therapist and those who had abnormal voice quality or reported several vocal symptoms were referred to a clinical examination by a laryngologist. The results showed that 20% of this population reported two or more vocal symptoms during the previous year and that 19% had an organic voice disorder. This reinforces the need for clinical evaluation of students with vocal symptoms and more vocal training in the teacher education programs.

  16. 49 CFR 236.555 - Repaired or rewound receiver coil.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Repaired or rewound receiver coil. 236.555 Section 236.555 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... or rewound receiver coil. Receiver coil which has been repaired or rewound shall have the...

  17. The Roach muscle bundle and umbilical cord coiling

    NARCIS (Netherlands)

    de Laat, Monique W. M.; Nikkels, Peter G. J.; Franx, Arie; Visser, Gerard H. A.

    2007-01-01

    Objective: To determine if presence of the Roach muscle, a small muscle bundle tying just beside the umbilical artery, contributes to umbilical cord coiling. Methods: 251 umbilical cords were examined. The umbilical coiling index (UCI) was calculated as the number of coils divided by the cord length

  18. Transport of one SC coil through the village of Meyrin

    CERN Multimedia

    1956-01-01

    The energizing coils of the Synchro-cyclotron magnet were manufactured in Belgium before travelling to Basel in Switzerland by boat and continuing by road to Geneva. The first coil reached Geneva in December 1955, with the second following in early 1956. The coils were stored in a hangar at the Geneva airport before they were brought to CERN in May 1956.

  19. The training in epoxy-impregnated superconducting coils

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, H.; Bobrov, E.S.; Iwasa, Y.; Takaghi, T.; Tsukamoto, O.

    1985-03-01

    The authors have investigated the training of epoxy-impregnated superconducting coils. It has been observed that the boundary conditions at the coil ends have a crucial effect on shear-stress-induced epoxy cracks in the winding and consequently on the coil training. The results were quantified using acoustic emission data.

  20. Unconventional gradient coil designs in magnetic resonance imaging.

    Science.gov (United States)

    Zhu, Minhua; Xia, Ling; Liu, Feng

    2014-01-01

    In magnetic resonance imaging (MRI), the gradient coils are used to encode the spatial positions of protons by varying the magnetic field linearly across the imaging subject. With the latest development of MRI technique and new clinical and research applications, the gradient coil system requires increasingly innovative designs. In this paper, four unconventional gradient coil designs are reviewed: (1) local gradient coils; (2) new coil configurations with reduced peripheral nerve stimulation (PNS); (3) dedicated structures designed for hybrid systems (combining MRI with other medical devices); and (4) the full 3D coil designs. For the first type, the development of local gradient coils (mainly head coils) is discussed chronologically and divided into three stages: the "golden" stage in the 1990s, the "wane" stage in the 2000s, and the "revival" stage in the 2010s. For the second type, various designs for the reduction of PNS problems have been described, including local and whole-body gradient coil systems. For the third design, a dedicated gradient coil design for multi-modality combination is illustrated with an MRI-LINAC system. Finally, gradient systems with non-layered coil structure are described in the fourth design type. We hope that this review on unconventional gradient coil designs will be useful for the new development of MRI technology and emerging medical applications.

  1. Modeling Endovascular MRI Coil Coupling with Transmit RF Excitation

    Science.gov (United States)

    Venkateswaran, Madhav; Unal, Orhan; Hurley, Samuel; Samsonov, Alexey; Wang, Peng; Fain, Sean; Kurpad, Krishna

    2016-01-01

    Objective To model inductive coupling of endovascular coils with transmit RF excitation for selecting coils for MRI-guided interventions. Methods Independent and computationally efficient FEM models are developed for the endovascular coil, cable, transmit excitation and imaging domain. Electromagnetic and circuit solvers are coupled to simulate net B1+ fields and induced currents and voltages. Our models are validated using the Bloch Siegert B1+ mapping sequence for a series-tuned multimode coil, capable of tracking, wireless visualization and high resolution endovascular imaging. Results Validation shows good agreement at 24, 28 and 34 μT background RF excitation within experimental limitations. Quantitative coil performance metrics agree with simulation. A parametric study demonstrates trade off in coil performance metrics when varying number of coil turns. Tracking, imaging and wireless marker multimode coil features and their integration is demonstrated in a pig study. Conclusion Developed models for the multimode coil were successfully validated. Modeling for geometric optimization and coil selection serves as a precursor to time-consuming and expensive experiments. Specific applications demonstrated include parametric optimization, coil selection for a cardiac intervention and an animal imaging experiment. Significance Our modular, adaptable and computationally efficient modeling approach enables rapid comparison, selection and optimization of inductively-coupled coils for MRI-guided interventions. PMID:26960218

  2. A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide.

    Science.gov (United States)

    Hagelueken, Gregor; Clarke, Bradley R; Huang, Hexian; Tuukkanen, Anne; Danciu, Iulia; Svergun, Dmitri I; Hussain, Rohanah; Liu, Huanting; Whitfield, Chris; Naismith, James H

    2015-01-01

    Long-chain bacterial polysaccharides have important roles in pathogenicity. In Escherichia coli O9a, a model for ABC transporter-dependent polysaccharide assembly, a large extracellular carbohydrate with a narrow size distribution is polymerized from monosaccharides by a complex of two proteins, WbdA (polymerase) and WbdD (terminating protein). Combining crystallography and small-angle X-ray scattering, we found that the C-terminal domain of WbdD contains an extended coiled-coil that physically separates WbdA from the catalytic domain of WbdD. The effects of insertions and deletions in the coiled-coil region were analyzed in vivo, revealing that polymer size is controlled by varying the length of the coiled-coil domain. Thus, the coiled-coil domain of WbdD functions as a molecular ruler that, along with WbdA:WbdD stoichiometry, controls the chain length of a model bacterial polysaccharide.

  3. Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting.

    Science.gov (United States)

    Zacco, Elsa; Hütter, Julia; Heier, Jason L; Mortier, Jérémie; Seeberger, Peter H; Lepenies, Bernd; Koksch, Beate

    2015-09-18

    The coiled-coil folding motif represents an ideal scaffold for the defined presentation of ligands due to the possibility of positioning them at specific distances along the axis. We created a coiled-coil glycopeptide library to characterize the distances between the carbohydrate-binding sites of the asialoglycoprotein receptors (ASGPR) on hepatocytes. The components of the glycopeptide library vary for the number of displayed ligands (galactose), their position on the peptide sequence, and the space between peptide backbone and carbohydrate. We determined the binding of the glycopeptides to the hepatocytes, and we established the optimal distance and orientation of the galactose moieties for interaction with the ASGPR using flow cytometry. We confirmed that the binding occurs through endocytosis mediated by ASGPR via inhibition studies with cytochalasin D; fluorescence microscopy studies display the uptake of the carrier peptides inside the cell. Thus, this study demonstrates that the coiled-coil motif can be used as reliable scaffold for the rational presentation of ligands.

  4. CENP-K and CENP-H may form coiled-coils in the kinetochores

    Institute of Scientific and Technical Information of China (English)

    QIU ShuLan; WANG JiaNing; YU Chuang; HE DaCheng

    2009-01-01

    Kinetochores are large proteinaceous structure on the surface of chromosomes' primary constriction during mitosis. They link chromosomes to spindle microtubules and also regulate the spindle assem-bly checkpoint, which is crucial for correct chromosome segregation in all eukaryotes. The better known core networks of kinetochores include the KMN network (K, KNL1; M, Mis12 complex; N, Ndc80 complex)and CCAN (constitutive centromere-associated network). However, the detailed molecular mechanism of the kinetochore protein network remains unclear. This study demonstrates that CENP-H and CENP-K form quite stable subcomplex by TAP (tandem affinity purification) with HEK 293 cells which express TAP-CENP-K, with the ratio of purified CENP-H and CENP-K being close to 1 : 1 even with high salt. Bioinformatic analysis suggests that CENP-H and CENP-K are enriched with coiled-coil regions. This implies that CENP-H and CENP-K form heterodimeric coiled-coils. Furthermore, the func-tional regions which form the complex are respectively located on their N- and C-terminals, but the association between the C-terminals is more complex. It is possible that this is the first identified het-erodimeric coiled-coils within the inner kinetochore, which is directly involved in the attachment be-tween kinetochores and the spindle microtubules.

  5. Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

    Science.gov (United States)

    Kuhn, Michael; Hyman, Anthony A.; Beyer, Andreas

    2014-01-01

    Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its functional repertoire through the course of evolution. We developed a refined sequence alignment technique that is more sensitive to coiled coil proteins, which are abundant in the centrosome. For proteins with high coiled-coil content, our algorithm identified 17% more reciprocal best hits than BLAST. Analyzing 108 eukaryotic genomes, we traced the evolutionary history of centrosome proteins. In order to assess how these proteins formed the centrosome and adopted new functions, we computationally emulated evolution by iteratively removing the most recently evolved proteins from the centrosomal protein interaction network. Coiled-coil proteins that first appeared in the animal–fungi ancestor act as scaffolds and recruit ancestral eukaryotic proteins such as kinases and phosphatases to the centrosome. This process created a signaling hub that is crucial for multicellular development. Our results demonstrate how ancient proteins can be co-opted to different cellular localizations, thereby becoming involved in novel functions. PMID:24901223

  6. CENP-K and CENP-H may form coiled-coils in the kinetochores

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Kinetochores are large proteinaceous structure on the surface of chromosomes’ primary constriction during mitosis. They link chromosomes to spindle microtubules and also regulate the spindle assem- bly checkpoint, which is crucial for correct chromosome segregation in all eukaryotes. The better known core networks of kinetochores include the KMN network (K, KNL1; M, Mis12 complex; N, Ndc80 complex)and CCAN (constitutive centromere-associated network). However, the detailed molecular mechanism of the kinetochore protein network remains unclear. This study demonstrates that CENP-H and CENP-K form quite stable subcomplex by TAP (tandem affinity purification) with HEK 293 cells which express TAP-CENP-K, with the ratio of purified CENP-H and CENP-K being close to 1︰1 even with high salt. Bioinformatic analysis suggests that CENP-H and CENP-K are enriched with coiled-coil regions. This implies that CENP-H and CENP-K form heterodimeric coiled-coils. Furthermore, the func- tional regions which form the complex are respectively located on their N- and C-terminals, but the association between the C-terminals is more complex. It is possible that this is the first identified het- erodimeric coiled-coils within the inner kinetochore, which is directly involved in the attachment be- tween kinetochores and the spindle microtubules.

  7. Possible fabrication techniques and welding specifications for the external cylinder of the CMS coil

    CERN Document Server

    Castoldi, M; Desirelli, Alberto; Favre, G; Losasso, M; Sequeira-Lopes-Tavares, S; Sgobba, Stefano; Tardy, T; Levesy, B; Reytier, M

    2000-01-01

    The Compact Muon Solenoid (CMS) is one of the experiments, which are being designed in the framework of the Large Hadron Collider (LHC) project at CERN. The design field of the CMS magnet is 4 T, the magnetic length is 12.5 m and the free aperture is 6 m in diameter. This is achieved with a 4 layer and 5 module superconducting Al- stabilized coil energized at a nominal current of 20 kA at 4.5 K. In the CMS coil the structural function is ensured, unlike in other existing Al-stabilized thin solenoids, both by the Al-alloy reinforced conductor and the external cylinder. The calculated stress level in the cylinder at operating conditions is particularly severe. In this paper the different possible fabrication techniques are assessed and compared and a possible welding specification for this component is given. (9 refs).

  8. 7 CFR 51.2850 - Diameter.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Diameter. Diameter means the greatest dimension measured at right angles to a straight line running from...

  9. 7 CFR 51.712 - Diameter.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... § 51.712 Diameter. Diameter means the greatest dimension measured at right angles to a line from stem...

  10. 7 CFR 51.651 - Diameter.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946...) Definitions § 51.651 Diameter. Diameter means the greatest dimension measured at right angles to a line from...

  11. Measuring angular diameters of extended sources

    NARCIS (Netherlands)

    van Hoof, PAM

    2000-01-01

    When measuring diameters of partially resolved sources like planetary nebulae, H II regions or galaxies, often a technique called Gaussian deconvolution is used. This technique yields a Gaussian diameter, which subsequently has to be multiplied by a conversion factor to obtain the true angular

  12. Influence of classroom acoustics on the voice levels of teachers with and without voice problems: a field study

    DEFF Research Database (Denmark)

    Pelegrin Garcia, David; Lyberg-Åhlander, Viveka; Rydell, Roland

    2010-01-01

    Many teachers suffer from voice problems and classroom acoustics has been considered as one of the potential hazards for this. The present study examines how classroom acoustics interacts with the voices of 14 teachers without voice problems and 13 teachers with voice problems. The assessment...... of Reverberation Time and Voice Support were measured in the 30 empty classrooms of the study. An empirical model shows that the measured voice levels depended on the activity noise levels and the voice support. Teachers with and without voice problems were differently affected by the voice support...... of the classroom. The results thus suggest that teachers with voice problems are more aware of classroom acoustic conditions than their healthy colleagues and make use of the more supportive rooms to lower their voice levels. This behavior may result from an adaptation process of the teachers with voice problems...

  13. Solutions for Safe Hot Coil Evacuation and Coil Handling in Case of Thick and High Strength Steel

    OpenAIRE

    Sieberer Stefan; Pichler Lukas; Hackl Manfred

    2016-01-01

    Currently hot rolling plants are entering the market segment for thick gauges and high strength steel grades where the elastic bending property of the strip leads to internal forces in the coil during coiling operation. The strip tends to open. Primetals is investigating several possibilities to facilitate safe coil evacuation and coil handling under spring-back conditions. The contribution includes finite element models of such mechanical solutions. Results of parameter variation and stabili...

  14. Flow pattern-based mass and heat transfer and frictional drag of gas-non-Newtonian liquid flow in helical coil: two- and three-phase systems

    Science.gov (United States)

    Thandlam, Anil Kumar; Das, Chiranjib; Majumder, Subrata Kumar

    2016-08-01

    Investigation of wall-liquid mass transfer and heat transfer phenomena with gas-Newtonian and non-Newtonian fluids in vertically helical coil reactor have been reported in this article. Experiments were conducted to investigate the effect of various dynamic and geometric parameters on mass and heat transfer coefficients in the helical coil reactor. The flow pattern-based heat and mass transfer phenomena in the helical coil reactor are highlighted at different operating conditions. The study covered a wide range of geometric parameters such as diameter of the tube (d t ), diameter of the coil (D c ), diameter of the particle (d p ), pitch difference (p/D c ) and concentrations of non-Newtonian liquid. The correlation models for the heat and mass transfer coefficient based on the flow pattern are developed which may be useful in process scale-up of the helical coil reactor for industrial application. The frictional drag coefficient was also estimated and analyzed by mass transfer phenomena based on the electrochemical method.

  15. An experimental study of the flow of LPG as refrigerant inside an adiabatic helical coiled capillary tube in vapour compression refrigeration system

    Science.gov (United States)

    Punia, Sanjeev Singh; Singh, Jagdev

    2015-11-01

    This paper presents an experimental investigation for the flow of liquefied petroleum gas (LPG) as a refrigerant inside an adiabatic helically coiled capillary tube in vapour compression refrigeration system. The effect of various geometric parameters and operating conditions like capillary tube inner diameter, length of capillary tube, coil diameter and different inlet subcoolings on the mass flow rate of LPG through the helical coiled capillary tube geometry has been investigated. It has been established that the coil diameter significantly influences the mass flow rate of LPG through the adiabatic helical capillary tube. It has been concluded that the effect of coiling of capillary tube reduces the mass flow rate by 5-12 % as compared to those of the straight capillary tube operating under similar conditions. The data obtained from the experiments are analyzed and a dimensionless correlation has been developed. The proposed correlation predicts that more than 90 % of experimental data which is in agreement with measured data in an error band of ±10 %.

  16. Computational study for the effects of coil configuration on blood flow characteristics in coil-embolized cerebral aneurysm.

    Science.gov (United States)

    Otani, Tomohiro; Ii, Satoshi; Shigematsu, Tomoyoshi; Fujinaka, Toshiyuki; Hirata, Masayuki; Ozaki, Tomohiko; Wada, Shigeo

    2016-07-21

    Coil embolization of cerebral aneurysms with inhomogeneous coil distribution leads to an incomplete occlusion of the aneurysm. However, the effects of this factor on the blood flow characteristics are still not fully understood. This study investigates the effects of coil configuration on the blood flow characteristics in a coil-embolized aneurysm using computational fluid dynamics (CFD) simulation. The blood flow analysis in the aneurysm with coil embolization was performed using a coil deployment (CD) model, in which the coil configuration was constructed using a physics-based simulation of the CD. In the CFD results, total flow momentum and kinetic energy in the aneurysm gradually decayed with increasing coil packing density (PD), regardless of the coil configuration attributed to deployment conditions. However, the total shear rate in the aneurysm was relatively high and the strength of the local shear flow varied based on the differences in coil configuration, even at adequate PDs used in clinical practice (20-25 %). Because the sufficient shear rate reduction is a well-known factor in the blood clot formation occluding the aneurysm inside, the present study gives useful insight into the effects of coil configuration on the treatment efficiency of coil embolization.

  17. Study on the performance improvement of the high temperature superconducting coil with several separated coils at the edges

    Science.gov (United States)

    Ishiguri, S.; Oka, T.; Fukui, S.; Ogawa, J.; Sato, T.

    2008-09-01

    In designing high temperature superconducting (HTS) coils, it is important to secure large magnetic fields and stored energy using shorter tape length. Thus, it is necessary to improve the transport current performance of the coils. The critical current and n-value of an HTS tape depend on magnetic fields and flux angles under constant temperature. Considering these dependencies, we established a model to analyze coil critical current. This model clarifies that relatively large electric fields are generated at the coil edges. This adversely affects the transport current performance. In this study, the coil edge is separated into several coils, keeping the total tape length constant. This increases the coil critical current, stored energy, central magnetic field, and also the coil volume, which contains vacancies created by the separation. To estimate coil performance, we calculated the stored energy density, whose denominator is the increased coil volume. This stored energy density reaches its maximum value when the number of the separated coils is eight. At this optimum separation, the central magnetic field increases by 13%, and the stored energy improves by 43%, compared to a rectangular coil wound with the same tape length.

  18. Structural attributes for the recognition of weak and anomalous regions in coiled-coils of myosins and other motor proteins

    Directory of Open Access Journals (Sweden)

    Sunitha Margaret S

    2012-09-01

    Full Text Available Abstract Background Coiled-coils are found in different proteins like transcription factors, myosin tail domain, tropomyosin, leucine zippers and kinesins. Analysis of various structures containing coiled-coils has revealed the importance of electrostatic and hydrophobic interactions. In such domains, regions of different strength of interactions need to be identified since they could be biologically relevant. Findings We have updated our coiled-coil validation webserver, now called COILCHECK+, where new features were added to efficiently identify the strength of interaction at the interface region and measure the density of charged residues and hydrophobic residues. We have examined charged residues and hydrophobic ladders, using a new algorithm called CHAHO, which is incorporated within COILCHECK + server. CHAHO permits the identification of spatial charged residue patches and the continuity of hydrophobic ladder which stabilizes and destabilizes the coiled-coil structure. Conclusions The availability of such computational tools should be useful to understand the importance of spatial clustering of charged residues and the continuity of hydrophobic residues at the interface region of coiled-coil dimers. COILCHECK + is a structure based tool to validate coiled-coil stability; it can be accessed at http://caps.ncbs.res.in/coilcheckplus.

  19. Subunit b-dimer of the Escherichia coli ATP synthase can form left-handed coiled-coils.

    Science.gov (United States)

    Wise, John G; Vogel, Pia D

    2008-06-01

    One remaining challenge to our understanding of the ATP synthase concerns the dimeric coiled-coil stator subunit b of bacterial synthases. The subunit b-dimer has been implicated in important protein interactions that appear necessary for energy conservation and that may be instrumental in energy conservation during rotary catalysis by the synthase. Understanding the stator structure and its interactions with the rest of the enzyme is crucial to the understanding of the overall catalytic mechanism. Controversy exists on whether subunit b adopts a classic left-handed or a presumed right-handed dimeric coiled-coil and whether or not staggered pairing between nonhomologous residues in the homodimer is required for intersubunit packing. In this study we generated molecular models of the Escherichia coli subunit b-dimer that were based on the well-established heptad-repeat packing exhibited by left-handed, dimeric coiled-coils by employing simulated annealing protocols with structural restraints collected from known structures. In addition, we attempted to create hypothetical right-handed coiled-coil models and left- and right-handed models with staggered packing in the coiled-coil domains. Our analyses suggest that the available structural and biochemical evidence for subunit b can be accommodated by classic left-handed, dimeric coiled-coil quaternary structures.

  20. Numerical Analysis of a Flexible Dual Loop Coil and its Experimental Validation for pre-Clinical Magnetic Resonance Imaging of Rodents at 7 T

    Science.gov (United States)

    Solis-Najera, S.; Vazquez, F.; Hernandez, R.; Marrufo, O.; Rodriguez, A. O.

    2016-12-01

    A surface radio frequency coil was developed for small animal image acquisition in a pre-clinical magnetic resonance imaging system at 7 T. A flexible coil composed of two circular loops was developed to closely cover the object to be imaged. Electromagnetic numerical simulations were performed to evaluate its performance before the coil construction. An analytical expression of the mutual inductance for the two circular loops as a function of the separation between them was derived and used to validate the simulations. The RF coil is composed of two circular loops with a 5 cm external diameter and was tuned to 300 MHz and 50 Ohms matched. The angle between the loops was varied and the Q factor was obtained from the S11 simulations for each angle. B1 homogeneity was also evaluated using the electromagnetic simulations. The coil prototype was designed and built considering the numerical simulation results. To show the feasibility of the coil and its performance, saline-solution phantom images were acquired. A correlation of the simulations and imaging experimental results was conducted showing a concordance of 0.88 for the B1 field. The best coil performance was obtained at the 90° aperture angle. A more realistic phantom was also built using a formaldehyde-fixed rat phantom for ex vivo imaging experiments. All images showed a good image quality revealing clearly defined anatomical details of an ex vivo rat.

  1. The design of a digital voice data compression technique for orbiter voice channels

    Science.gov (United States)

    1975-01-01

    Voice bandwidth compression techniques were investigated to anticipate link margin difficulties in the shuttle S-band communication system. It was felt that by reducing the data rate on each voice channel from the baseline 24 (or 32) Kbps to 8 Kbps, additional margin could be obtained. The feasibility of such an alternate voice transmission system was studied. Several factors of prime importance that were addressed are: (1) achieving high quality voice at 8 Kbps; (2) performance in the presence of the anticipated shuttle cabin environmental noise; (3) performance in the presence of the anticipated channel error statistics; and (4) minimal increase in size, weight, and power over the current baseline voice processor.

  2. Planar quadrature coil design using shielded-loop resonators

    DEFF Research Database (Denmark)

    Stensgaard, A

    1997-01-01

    The shielded-loop resonator is known to have a low capacitive sample loss due to a perfect balancing. In this paper, it is demonstrated that shielded-loop technology also can be used to improve design of planar quadrature coils. Both a dual-loop circuit and especially a dual-mode circuit may...... benefit from use of shielded-loop resonators. Observations in measurements agree with theory for both a dual-loop coil and a dual-mode coil. The coils were designed for use as transmit/receive coil for 1H imaging and spectroscopy at 4.7 T in rat brain....

  3. Application of Microstructure Engineering in Steel Coil Cooling Process

    Institute of Scientific and Technical Information of China (English)

    LIU Zheng-dong; D Q Jin; I V Samarasekera; J K Brimacombe

    2005-01-01

    The coil cooling and its role in a hot strip mill were reviewed.A mathematical model was developed to describe and analyze the thermal history and its impact on precipitation phenomena during coil cooling for plain car bon,HSLA-V and HSLA-Nb steels.The predicted result of the thermal model was compared with that measured from industrial coil.The effect of cooling condition and coil dimension on the thermal history and final mechanical properties of the steel strip was examined.The coiling temperature and cooling rate have crucial influence on the precipitation strengthening.

  4. Superconducting coil system and methods of assembling the same

    Science.gov (United States)

    Rajput-Ghoshal, Renuka; Rochford, James H.; Ghoshal, Probir K.

    2016-01-19

    A superconducting magnet apparatus is provided. The superconducting magnet apparatus includes a power source configured to generate a current; a first switch coupled in parallel to the power source; a second switch coupled in series to the power source; a coil coupled in parallel to the first switch and the second switch; and a passive quench protection device coupled to the coil and configured to by-pass the current around the coil and to decouple the coil from the power source when the coil experiences a quench.

  5. Mechanical characteristics of the ATLAS B0 model coil

    CERN Document Server

    Foussat, A; Dudarev, A; Mayri, C; Miele, P; Sun, Z; ten Kate, H H J; Volpini, G

    2003-01-01

    The ATLAS B0 model coil has been tested at CERN to verify the design parameters of the Barrel Toroid coils (BT). The mechanical behavior of the B0 superconducting coil and its support structure is reported and compared with coil design calculations. The mechanical stresses and structural force levels during cooling down and excitation phases were monitored using strain gauges, position sensors and capacitive force transducers instrumentation. In the ATLAS magnet test facility, a magnetic mirror is used to reproduce the electromagnetic forces present in the BT coils, once these are assembled in toroid in the underground cavern in 2004. (8 refs).

  6. SSC (Superconducting Super Collider) dipole coil production tooling

    Energy Technology Data Exchange (ETDEWEB)

    Carson, J.A.; Barczak, E.J.; Bossert, R.C.; Brandt, J.S.; Smith, G.A.

    1989-03-01

    Superconducting Super Collider dipole coils must be produced to high precision to ensure uniform prestress and even conductor distribution within the collared coil assembly. Tooling is being prepared at Fermilab for the production of high precision 1M and 16.6M SSC dipole coils suitable for mass production. The design and construction methods builds on the Tevatron tooling and production experience. Details of the design and construction methods and measured coil uniformity of 1M coils will be presented. 4 refs., 10 figs.

  7. Random coil chemical shift for intrinsically disordered proteins

    DEFF Research Database (Denmark)

    Kjærgaard, Magnus; Brander, Søren; Poulsen, Flemming Martin

    2011-01-01

    . Temperature has a non-negligible effect on the (13)C random coil chemical shifts, so temperature coefficients are reported for the random coil chemical shifts to allow extrapolation to other temperatures. The pH dependence of the histidine random coil chemical shifts is investigated in a titration series......, which allows the accurate random coil chemical shifts to be obtained at any pH. By correcting the random coil chemical shifts for the effects of temperature and pH, systematic biases of the secondary chemical shifts are minimized, which will improve the reliability of detection of transient secondary...

  8. Going flat out : Collin Morris, a former roughneck-turned inventor, develops a radically different form of coiled tubing

    Energy Technology Data Exchange (ETDEWEB)

    Byfield, M.

    2009-11-15

    This article described a radically reshaped coiled tubing product developed by an engineer with CJS Coiled Tubing Supply Ltd. The method encapsulates multiple conduits and electric wires within a single coiled tubing umbilical. The product is manufactured in Texas where coiled tubing strings are braided and encased within a wrapping. The strings have to be braided to maintain uniform lengths when the tubing is spooled. CJS has developed a reputation as a technical coiled tubing problem solver, particularly for low-pressure gas wells where produced water must be removed in order to avoid build up. Round pipe is particularly difficult to braid if the various conduits are of different sizes and materials. The CJS solution is called FLATpak in which multiple conduits sit side by side, encased within a rectangular matrix of thermo plastic. Several configurations of conduit are possible, including various diameters and different electric wire. FLATpak is pressure-extruded as a single piece. The rectangular product coils tighter on a coiled tubing spool than round pipe, thereby reducing transportation costs. Steel blowout preventer (BOP) rams can be switched easily to the new shape as long as the rectangular form is solid and rounded at the corners. Many producers recognize the need to deploy artificial lift systems in low-rate gas wells. CJS has installed 30 permanent FLATpak systems in Canada, more than 10 in the United States, and is adding 4 or 5 more per month. CJS is also working to proof its umbilicals for higher pressures and temperatures, for possible offshore potential. 2 figs.

  9. Experimental investigation of heat transfer and pressure drop of turbulent flow inside tube with inserted helical coils

    Science.gov (United States)

    Sharafeldeen, M. A.; Berbish, N. S.; Moawed, M. A.; Ali, R. K.

    2016-08-01

    The heat transfer and pressure drop were experimentally investigated in a coiled wire inserted tube in turbulent flow regime in the range of Reynolds number of 14,400 ≤ Re ≤ 42,900. The present work aims to extend the experimental data available on wire coil inserts to cover wire diameter ratio of 0.044 ≤ e/d ≤ 0.133 and coil pitch ratio of 1 ≤ p/d ≤ 5. Uniform heat flux was applied to the external surface of the tube and air was selected as fluid. The effects of Reynolds number and wire diameter and coil pitch ratios on the Nusselt number and friction factor were studied. The enhancement efficiency and performance criteria ranges are of (46.9-82.6 %) and (100.1-128 %) within the investigated range of the different parameters, respectively. Correlations are obtained for the average Nusselt number and friction factor utilizing the present measurements within the investigated range of geometrical parameters and Re. The maximum deviation between correlated and experimental values for Nusselt number and friction factor are ±5 and ±6 %, respectively.

  10. Studies on the Performance of Different Coiled Column Configurations for Compact Type-I Counter-current Chromatography

    Science.gov (United States)

    Yang, Yi; Gu, Dongyu; Aisa, Haji Akber; Ito, Yoichiro

    2011-01-01

    Three types of novel coiled column configurations, i.e., a triangular coiled column and elliptical coiled columns I and II, were designed for type-I countercurrent chromatography and their performances were evaluated with two solvent systems each with suitable test samples. Three DNP-amino acids (DNP-DL-glu, DNP-β-ala and DNP-L-ala) were separated with a moderately hydrophobic two-phase solvent system composed of hexane-ethyl acetate-metanol-0.1M hydrochloric acid (1:1:1:1, v/v), while two dipeptides (tryptophyl tyrosine and valyl-tyrosine) were separated with a polar solvent system composed of 1-butanol-acetic acid-water (4.75:0.25:5, v/v). The overall results indicated that the performance of compact type-I counter-current chromatography was improved by elliptical coiled column II which was mounted with its maximum coil diameter perpendicular to the surface of the column holder. Hydrodynamic effects involved in these separations were discussed. PMID:21491597

  11. Experimental Study of Heat Transfer Enhancement in a Heated Tube Caused by Wire-Coil and Rings

    Directory of Open Access Journals (Sweden)

    Saeed Vahidifar

    2015-01-01

    Full Text Available This study investigates heat transfer characteristics and the pressure drop of a horizontal double pipe heat exchanger with wire coil inserts. The amplification of convection heat transfer coefficient in the heat exchanger reduces the weight, size and cost of heat exchanger. One way of augmenting the heat transfer is to disturb the boundary layer. When an object is placed in a boundary layer, it affects the flow structure and alters the velocity and thermal profiles. The change is affected by the formation of jets and wakes in the boundary layer as it alters modifies transfer and friction coefficients on the wall. This paper studies the characteristics of the heat transfer and the pressure drop of a double pipe horizontal tube heat exchanger with an inserted wire coil and rings. Wire coil acts as a swirl flow, which increases turbulence and roughness whereas rings increase heat transfer as a promoter of turbulence and roughness. The experimental data sets were extracted from wire coils and rings tested within a geometrical range with a pitch of (P/D=1, 2, 4 and wire diameter of (d/D=0.05, 0.07, 0.11. For wire coil with d/D=0.11, P/D =1 and Reynolds number of 10000, the overall enhancement efficiency amounted to 128%.

  12. The SMC (Short Model Coil) dipole: An R&D program for Nb3Sn accelerator magnets

    CERN Document Server

    Perez, J C; Bordini, B; Canfer, S; Ellwood, G; Feuvrier, J; Guinchard, M; Karppinen, M; Kokkinos, C; Manil, P; Milanese, A; Oberli, L; Regis, F; de Rijk, G

    2012-01-01

    The Short Model Coil (SMC) assembly has been designed, as test bench for short racetrack coils wound with Nb3Sn cable. The mechanical structure comprises an iron yoke surrounded by a 20 mm thick aluminium alloy shell, and includes four loading pads that transmit the required pre-compression from the outer shell into the two coils. The outer shell is pre-tensioned with mechanical keys that are inserted with the help of pressurized bladders and two 30 mm diameter aluminium alloy rods provide the axial loading to the coil ends. The outer shell, the axial rods, and the coils are instrumented with strain gauges, which allow precise monitoring of the loading conditions during the assembly and at cryogenic temperature during the magnet test. Two SMC assemblies have been completed and cold tested in the frame of a European collaboration between CEA (FR), CERN and STFC (UK) and with the technical support from LBNL (US). This paper describes the main features of the SMC assembly, the experience from the dummy assembli...

  13. The Short Model Coil (SMC) dipole: an R&D program towards Nb3Sn accelerator magnets

    CERN Document Server

    Bajko, M; Canfer, S; Ellwood, G; Feuvrier, J; Guinchard, M; Karppinen, M; Kokkinos, C; Manil, P; Milanese, A; Oberli, L; Perez, J-C; Regis, F; de Rijk, G

    2011-01-01

    The Short Model Coil (SMC) assembly has been designed, as test bench for short racetrack coils wound with Nb3Sn cable. The mechanical structure comprises an iron yoke surrounded by a 20 mm thick aluminium alloy shell, and includes four loading pads that transmit the required pre-compression from the outer shell into the two coils. The outer shell is pre-tensioned with mechanical keys that are inserted with the help of pressurized bladders and two 30 mm diameter aluminium alloy rods provide the axial loading to the coil ends. The outer shell, the axial rods, and the coils are instrumented with strain gauges, which allow precise monitoring of the loading conditions during the assembly and at cryogenic temperature during the magnet test. Two SMC assemblies have been completed and cold tested in the frame of a European collaboration between CEA (FR), CERN and STFC (UK) and with the technical support from LBNL (US). This paper describes the main features of the SMC assembly, the experience from the dummy assemblie...

  14. Muscular tension and body posture in relation to voice handicap and voice quality in teachers with persistent voice complaints.

    Science.gov (United States)

    Kooijman, P G C; de Jong, F I C R S; Oudes, M J; Huinck, W; van Acht, H; Graamans, K

    2005-01-01

    The aim of this study was to investigate the relationship between extrinsic laryngeal muscular hypertonicity and deviant body posture on the one hand and voice handicap and voice quality on the other hand in teachers with persistent voice complaints and a history of voice-related absenteeism. The study group consisted of 25 female teachers. A voice therapist assessed extrinsic laryngeal muscular tension and a physical therapist assessed body posture. The assessed parameters were clustered in categories. The parameters in the different categories represent the same function. Further a tension/posture index was created, which is the summation of the different parameters. The different parameters and the index were related to the Voice Handicap Index (VHI) and the Dysphonia Severity Index (DSI). The scores of the VHI and the individual parameters differ significantly except for the posterior weight bearing and tension of the sternocleidomastoid muscle. There was also a significant difference between the individual parameters and the DSI, except for tension of the cricothyroid muscle and posterior weight bearing. The score of the tension/posture index correlates significantly with both the VHI and the DSI. In a linear regression analysis, the combination of hypertonicity of the sternocleidomastoid, the geniohyoid muscles and posterior weight bearing is the most important predictor for a high voice handicap. The combination of hypertonicity of the geniohyoid muscle, posterior weight bearing, high position of the hyoid bone, hypertonicity of the cricothyroid muscle and anteroposition of the head is the most important predictor for a low DSI score. The results of this study show the higher the score of the index, the higher the score of the voice handicap and the worse the voice quality is. Moreover, the results are indicative for the importance of assessment of muscular tension and body posture in the diagnosis of voice disorders.

  15. Spontaneous quenches of a high temperature superconducting pancake coil

    Energy Technology Data Exchange (ETDEWEB)

    Lue, J.W.; Lubell, M.S. [Oak Ridge National Lab., TN (United States); Aized, D.; Campbell, J.M.; Schwall, R.E. [American Superconductor Corp., Westborough, MA (United States)

    1995-09-01

    A double-pancake coil made of Bi-2223/Ag high temperature superconducting (HTS) tape was constructed with an embedded heater and graded conductors to study the stability and quench propagation in HTS coils. The experiments were performed with liquid nitrogen and gaseous helium cooling in temperatures ranging from 5 to 77 K. The coil was very stable, and no ``normal`` zone was sustained or propagated with local pulsed heating. However, spontaneous quenches of the cod were experienced. This was found to be the result of having the coil current higher than that of the lower I{sub c} sections of the coil for a long time. This quench process took minutes to develop--much longer than would be expected in a low temperature superconducting coil. The quench behaved more like a spreading and continuous heating of an increasingly larger partially resistive section of the coil than like a sequential ``normal`` front propagation.

  16. Fabrication of the superconducting coils for Wendelstein 7-X

    Energy Technology Data Exchange (ETDEWEB)

    Risse, Konrad E-mail: konrad.risse@ipp.mpg.de; Rummel, Th.; Wegener, L.; Holzthuem, R.; Jaksic, N.; Kerl, F.; Sapper, J

    2003-09-01

    The Max Planck Institute of Plasma Physics is building up the stellarator fusion experiment Wendelstein 7-X (W7-X) at the branch institute in Greifswald. W7-X continues the line of stellarator experiments at IPP. To allow for steady state operation W7-X has a superconducting coil system with 50 non-planar and 20 planar coils. The coil system is grouped in five equal modules, each consisting of two mirror symmetric half modules. The half modules are assembled from five different non-planar coils, two planar coils and a sector of the coil support structure. All cryogenic parts are enclosed in a cryostat to protect them from ambient temperature. The magnet system was ordered from the European industry. The production of superconductor, winding packs and encasings are under way. The main focus of this contribution aims on the fabrication state of the coil system.

  17. Output beam analysis of high power COIL

    Institute of Scientific and Technical Information of China (English)

    Deli Yu(于德利); Fengting Sang(桑凤亭); Yuqi Jin(金玉奇); Yizhu Sun(孙以珠)

    2003-01-01

    As the output power of a chemical oxygen iodine laser (COIL) increases, the output laser beam instabilityappears as the far-field beam spot drift and deformation for the large Fresnel number unstable resonator.In order to interpret this phenomenon, an output beam mode simulation code was developed with the fastFourier transform method. The calculation results show that the presence of the nonuniform gain in COILproduces a skewed output intensity distribution, which causes the mirror tilt and bulge due to the thermalexpansion. With the output power of COIL increases, the mirror surfaces, especially the back surface ofthe scraper mirror, absorb more and more heat, which causes the drift and deformation of far field beamspot seriously. The initial misalignment direction is an important factor for the far field beam spot driftingand deformation.

  18. Theory of the quadrature elliptic birdcage coil.

    Science.gov (United States)

    Leifer, M C

    1997-11-01

    This paper presents the theory of the quadrature birdcage coil wound on an elliptic cylindrical former. A conformal transformation of the ellipse to a circular geometry is used to derive the optimal sampling of the continuous surface current distribution to produce uniform magnetic fields within an elliptic cylinder. The analysis is rigorous for ellipses of any aspect ratio and shows how to produce quadrature operation of the elliptic birdcage with a conventional hybrid combiner. Insight gained from the transformation is also used to analyze field homogeneity, find the optimal RF shield shape, and specify component values to produce the correct current distribution in practice. Measurements and images from a 16-leg elliptic birdcage coil at both low and high frequencies show good quadrature performance, homogeneity, and sensitivity.

  19. Magnetically Damped Furnace Bitter Magnet Coil 1

    Science.gov (United States)

    Bird, M. D.

    1997-01-01

    A magnet has been built by the National High Magnetic Field Laboratory for NASA on a cost reimbursement contract. The magnet is intended to demonstrate the technology and feasibility of building a magnet for space based crystal growth. A Bitter magnet (named after Francis Bitter, its inventor) was built consisting of four split coils electrically in series and hydraulically in parallel. The coils are housed in a steel vessel to reduce the fringe field and provide some on-axis field enhancement. The steel was nickel plated and Teflon coated to minimize interaction with the water cooling system. The magnet provides 0.14 T in a 184 mm bore with 3 kW of power.

  20. DC SQUIDS with planar input coils

    Energy Technology Data Exchange (ETDEWEB)

    Pegrum, C.M.; Donaldson, G.B.; Hutson, D.; Tugwell, A.

    1985-03-01

    We describe the key parts of our recent work to develop a planar thin-film DC SQUID with a closely-coupled spiral input coil. Our aim has been to make a device that is superior to present RF SQUID sensors in terms of sensitivity and long-term reliability. To be compatible with an RF SQUID the inductance of the input coils must be relatively large, typically 2..mu..H, and the input noise current in the white noise region should be below 10pA Hz /SUP -1/2/ . A low level of 1/f noise is also necessary for many applications and should be achieved without the use of complex noisecancelling circuitry. Our devices meet these criteria. We include a description of work on window and edge junction fabrication using ion beam cleaning, thermal oxidation and RF plasma processing.

  1. Using the Voice to Design Ceramics

    DEFF Research Database (Denmark)

    Hansen, Flemming Tvede; Jensen, Kristoffer

    2011-01-01

    SoundShaping, a system to create ceramics from the human voice. Based on a generic audio feature extraction system, and the principal component analysis to ensure that the pertinent information in the voice is used, a 3D shape is created using simple geometric rules. This shape is output to a 3D printer...

  2. The Voice of Conscience in Rousseau's Emile

    Science.gov (United States)

    Kodelja, Zdenko

    2015-01-01

    According to Rousseau, conscience and conscience alone can elevate human beings to a level above that of animals. It is conscience, understood as infallible judge of good and bad, which makes man like God. Conscience itself is, in this context, understood as divine, as an "immortal and celestial voice". Therefore, if the voice of…

  3. Why Is My Voice Changing? (For Teens)

    Science.gov (United States)

    ... enter puberty earlier or later than others. How Deep Will My Voice Get? How deep a guy's voice gets depends on his genes: ... of Use Notice of Nondiscrimination Visit the Nemours Web site. Note: All information on TeensHealth® is for ...

  4. Gender in voice perception in autism.

    NARCIS (Netherlands)

    Groen, W.B.; Orsouw, L van; Zwiers, M.; Swinkels, S.; Gaag, R.J. van der; Buitelaar, J.K.

    2008-01-01

    Deficits in the perception of social stimuli may contribute to the characteristic impairments in social interaction in high functioning autism (HFA). Although the cortical processing of voice is abnormal in HFA, it is unclear whether this gives rise to impairments in the perception of voice gender.

  5. Speaking with the voice of authority

    CERN Multimedia

    2002-01-01

    GPB Consulting has developed a scientific approach to voice coaching. A digital recording of the voice is sent to a lab in Switzerland and analyzed by a computer programme designed by a doctor of psychology and linguistics and a scientist at CERN (1 page).

  6. The Voice of Conscience in Rousseau's Emile

    Science.gov (United States)

    Kodelja, Zdenko

    2015-01-01

    According to Rousseau, conscience and conscience alone can elevate human beings to a level above that of animals. It is conscience, understood as infallible judge of good and bad, which makes man like God. Conscience itself is, in this context, understood as divine, as an "immortal and celestial voice". Therefore, if the voice of…

  7. Epidemiology of voice problems in Dutch teachers

    NARCIS (Netherlands)

    de Jong, F. I. C. R. S.; Kooijman, P. G. C.; Thomas, G.; Huinck, W. J.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to assess voice complaints and absence from work due to voice problems among teachers of primary and secondary education, as well as among a control group, 2,117 questionnaires were analysed. The total group consisted of 1,878 teachers and 239 controls. Female teachers more frequently repor

  8. Voice Deviations and Coexisting Communication Disorders.

    Science.gov (United States)

    St. Louis, Kenneth O.; And Others

    1992-01-01

    This study examined the coexistence of other communicative disorders with voice disorders in about 3,400 children in grades 1-12 at 100 sites throughout the United States. The majority of voice-disordered children had coexisting articulation deviations and also differed from controls on two language measures and mean pure-tone hearing thresholds.…

  9. Using the Voice to Design Ceramics

    DEFF Research Database (Denmark)

    Hansen, Flemming Tvede; Jensen, Kristoffer

    2011-01-01

    SoundShaping, a system to create ceramics from the human voice. Based on a generic audio feature extraction system, and the principal component analysis to ensure that the pertinent information in the voice is used, a 3D shape is created using simple geometric rules. This shape is output to a 3D printer...

  10. Epidemiology of voice problems in Dutch teachers.

    NARCIS (Netherlands)

    Jong, F.I.C.R.S. de; Kooijman, P.G.C.; Thomas, G.; Huinck, W.J.; Graamans, K.; Schutte, H.K.

    2006-01-01

    In order to assess voice complaints and absence from work due to voice problems among teachers of primary and secondary education, as well as among a control group, 2,117 questionnaires were analysed. The total group consisted of 1,878 teachers and 239 controls. Female teachers more frequently repor

  11. Epidemiology of voice problems in Dutch teachers

    NARCIS (Netherlands)

    de Jong, F. I. C. R. S.; Kooijman, P. G. C.; Thomas, G.; Huinck, W. J.; Graamans, K.; Schutte, H. K.

    2006-01-01

    In order to assess voice complaints and absence from work due to voice problems among teachers of primary and secondary education, as well as among a control group, 2,117 questionnaires were analysed. The total group consisted of 1,878 teachers and 239 controls. Female teachers more frequently repor

  12. Predictors of Choral Directors' Voice Handicap

    Science.gov (United States)

    Schwartz, Sandra

    2013-01-01

    Vocal demands of teaching are considerable and these challenges are greater for choral directors who depend on the voice as a musical and instructive instrument. The purpose of this study was to (1) examine choral directors' vocal condition using a modified Voice Handicap Index (VHI), and (2) determine the extent to which the major variables…

  13. Gender in Voice Perception in Autism

    Science.gov (United States)

    Groen, Wouter B.; van Orsouw, Linda; Zwiers, Marcel; Swinkels, Sophie; van der Gaag, Rutger Jan; Buitelaar, Jan K.

    2008-01-01

    Deficits in the perception of social stimuli may contribute to the characteristic impairments in social interaction in high functioning autism (HFA). Although the cortical processing of voice is abnormal in HFA, it is unclear whether this gives rise to impairments in the perception of voice gender. About 20 children with HFA and 20 matched…

  14. Voice Recognition: A New Assessment Tool?

    Science.gov (United States)

    Jones, Darla

    2005-01-01

    This article presents the results of a study conducted in Anchorage, Alaska, that evaluated the accuracy and efficiency of using voice recognition (VR) technology to collect oral reading fluency data for classroom-based assessments. The primary research question was as follows: Is voice recognition technology a valid and reliable alternative to…

  15. Two Factors Related to Effective Voice Interpreting.

    Science.gov (United States)

    Hurwitz, T. Alan

    1986-01-01

    Thirty-two interpreters for the deaf were measured on accuracy and quality of voice interpreting of the same story in two different sign language types: Pidgin Signed English and American Sign Language. Results indicated that previous experience interpreting was significantly related to the effectiveness of voice interpreting both languages.…

  16. Student Voice and the Common Core

    Science.gov (United States)

    Yonezawa, Susan

    2015-01-01

    Common Core proponents and detractors debate its merits, but students have voiced their opinion for years. Using a decade's worth of data gathered through design-research on youth voice, this article discusses what high school students have long described as more ideal learning environments for themselves--and how remarkably similar the Common…

  17. Student Voice and the Common Core

    Science.gov (United States)

    Yonezawa, Susan

    2015-01-01

    Common Core proponents and detractors debate its merits, but students have voiced their opinion for years. Using a decade's worth of data gathered through design-research on youth voice, this article discusses what high school students have long described as more ideal learning environments for themselves--and how remarkably similar the Common…

  18. Acute lung injury following refrigeration coil deicing.

    Science.gov (United States)

    McKeown, Nathanael J; Burton, Brent T

    2012-03-01

    We report a case of a worker who developed ALI requiring mechanical ventilatory support after attempting to melt ice condensate by applying the flame of an oxy-acetylene torch to refrigeration coils charged with a halocarbon refrigerant in a closed environment. A discussion of possible etiologies are discussed, including phosgene, carbonyl fluoride, and nitrogen oxides. Primary prevention with adequate respiratory protection is recommended whenever deicing is performed in a closed space environment.

  19. Voices from Around the Globe

    Directory of Open Access Journals (Sweden)

    Birgit Schreiber

    2017-07-01

    Full Text Available JSAA has been seeking to provide an opportunity for Student Affairs professionals and higher education scholars from around the globe to share their research and experiences of student services and student affairs programmes from their respective regional and institutional contexts. This has been given a specific platform with the guest-edited issue “Voices from Around the Globe” which is the result of a collaboration with the International Association of Student Affairs and Services (IASAS, and particularly with the guest editors, Kathleen Callahan and Chinedu Mba.

  20. Mechanical Resonances of Helically Coiled Carbon Nanowires

    Science.gov (United States)

    Saini, D.; Behlow, H.; Podila, R.; Dickel, D.; Pillai, B.; Skove, M. J.; Serkiz, S. M.; Rao, A. M.

    2014-07-01

    Despite their wide spread applications, the mechanical behavior of helically coiled structures has evaded an accurate understanding at any length scale (nano to macro) mainly due to their geometrical complexity. The advent of helically coiled micro/nanoscale structures in nano-robotics, nano-inductors, and impact protection coatings has necessitated the development of new methodologies for determining their shear and tensile properties. Accordingly, we developed a synergistic protocol which (i) integrates analytical, numerical (i.e., finite element using COMSOL®) and experimental (harmonic detection of resonance; HDR) methods to obtain an empirically validated closed form expression for the shear modulus and resonance frequency of a singly clamped helically coiled carbon nanowire (HCNW), and (ii) circumvents the need for solving 12th order differential equations. From the experimental standpoint, a visual detection of resonances (using in situ scanning electron microscopy) combined with HDR revealed intriguing non-planar resonance modes at much lower driving forces relative to those needed for linear carbon nanotube cantilevers. Interestingly, despite the presence of mechanical and geometrical nonlinearities in the HCNW resonance behavior the ratio of the first two transverse modes f2/f1 was found to be similar to the ratio predicted by the Euler-Bernoulli theorem for linear cantilevers.