WorldWideScience

Sample records for vocational progression pathways

  1. Finnish WorldSkills Achievers’ Vocational Talent Development and School-to-Work Pathways

    Directory of Open Access Journals (Sweden)

    Laura Pylväs

    2017-08-01

    Full Text Available This paper examines the perceptions of vocational expertise and school-to-work pathways among WorldSkills Competition (WSC achievers and their co-workers and employers within the Finnish context. At the biennial international WSC, young people (aged 18-to-23 years from over 60 countries demonstrate their skills in more than 40 trades. Individualized training for this competition is provided through the cooperation of vocational institutions (e.g., expert coaches, team leaders and competition panellists and industry (e.g., mentors, sponsors, materials, equipment. Semi-structured thematic interviews (N=51 were conducted in 2013 and 2014 with former Finnish WSC medal or diploma winners (n=18 who had since begun their working lives (1-to-15 years of work experience. Their employers (n=16 and colleagues (n=17 were also interviewed. Results showed that in addition to vocation-specific knowledge and skills, problem-solving skills, creativity, social skills and self-regulatory skills were acknowledged as the most significant elements of vocational expertise. The findings also indicated that formal vocational education combined with deliberate practice and training based on expert mentoring improved the long-term career progress and vocational expertise of the WSC achievers.

  2. Students’ Learning Performance and Transitions in Different Learning Pathways to Higher Vocational Education

    NARCIS (Netherlands)

    Biemans, Harm; Marien, Hans; Fleur, Erik; Tobi, Hilde; Nieuwenhuis, Loek; Runhaar, Piety

    2018-01-01

    To improve students’ transitions between successive educational levels, continuing learning pathways are being designed and implemented in many countries. This study was carried out to examine the effects of the Green Lycea (GL) as critical cases of continuing learning pathways in vocational

  3. The Relationship between Vocational Interests, Self-Efficacy, and Achievement in the Prediction of Educational Pathways

    Science.gov (United States)

    Patrick, Lyn; Care, Esther; Ainley, Mary

    2011-01-01

    The influence of vocational interest, self-efficacy beliefs, and academic achievement on choice of educational pathway is described for a cohort of Australian students. Participants were 189 students aged 14-15 years, who were considering either academic or applied learning pathways and subject choices for the final 3 years of secondary school.…

  4. Do Vocational Pathways Improve Higher Education Access for Women and Men from Less Privileged Social Backgrounds? : A Comparison of Vocational Tracks to Higher Education in France and Switzerland

    OpenAIRE

    Imdorf, Christian; Koomen, Maarten; Murdoch, Jake; Guégnard, Christine

    2017-01-01

    International audience; Educational policy developments in France and Switzerland have increased eligibility for higher education. This paper explores the extent to which vocationally orientated pathways to higher education reduce social inequalities in France and Switzerland. More specifically, we analyse how the vocational pathway facilitates access to higher education for male and female students from lower cultural capital backgrounds. We refer to gender theory to link young people's subj...

  5. [Various pathways leading to the progression of chronic liver diseases].

    Science.gov (United States)

    Egresi, Anna; Lengyel, Gabriella; Somogyi, Anikó; Blázovics, Anna; Hagymási, Krisztina

    2016-02-21

    As the result of various effects (viruses, metabolic diseases, nutritional factors, toxic agents, autoimmune processes) abnormal liver function, liver steatosis and connective tissue remodeling may develop. Progression of this process is complex including various pathways and a number of factors. The authors summarize the factors involved in the progression of chronic liver disease. They describe the role of cells and the produced inflammatory mediators and cytokines, as well as the relationship between the disease and the intestinal flora. They emphasize the role of oxidative stress, mitochondrial dysfunction and cell death in disease progression. Insulin resistance and micro-elements (iron, copper) in relation to liver damage are also discussed, and genetic and epigenetic aspects underlying disease progression are summarized. Discovery of novel treatment options, assessment of the effectiveness of treatment, as well as the success and proper timing of liver transplantation may depend on a better understanding of the process of disease progression.

  6. The experience of seeking, gaining and maintaining employment after traumatic spinal cord injury and the vocational pathways involved.

    Science.gov (United States)

    Hilton, Gillean; Unsworth, Carolyn A; Stuckey, Ruth; Murphy, Gregory C

    2018-01-01

    Vocational potential in people with spinal cord injury (SCI) are unrealised with rates of employment substantially lower than in the labour force participation of the general population and the pre-injury employment rates. To understand the experience and pathway of people achieving employment outcome after traumatic spinal cord injury by; classifying participants into employment outcome groups of stable, unstable and without employment; identifying pre and post-injury pathways for participants in each group and, exploring the experiences of people of seeking, gaining and maintaining employment. Thirty-one participants were interviewed. Mixed methods approach including interpretive phenomenological analysis and vocational pathway mapping of quantitative data. The most common pathway identified was from study and work pre-injury to stable employment post-injury. Four super-ordinate themes were identified from the interpretive phenomenological analysis; expectations of work, system impacts, worker identity and social supports. Implications for clinical practice include fostering cultural change, strategies for system navigation, promotion of worker identity and optimal use of social supports. The findings increase insight and understanding of the complex experience of employment after spinal cord injury. There is opportunity to guide experimental research, policy development and education concerning the complexity of the return to work experience and factors that influence pathways.

  7. Prioritising Progression over Proficiency: Limitations of Teacher-Based Assessment within Technician-Level Vocational Education

    Science.gov (United States)

    Carter, Alan; Bathmaker, Ann-Marie

    2017-01-01

    This article examines the evolution of assessment policy and practice in technician-level vocational education. Using the example of an advanced-level BTEC National programme in Engineering in one college in the UK, the article highlights how the origins of current assessment practice lie in genuine concerns since the late 1950s about the…

  8. Diverse Pathways of Psychology Majors: Vocational Interests, Self-Efficacy, and Intentions

    Science.gov (United States)

    Rottinghaus, Patrick J.; Gaffey, Abigail R.; Borgen, Fred H.; Ralston, Christopher A.

    2006-01-01

    The authors examine the differences in vocational interests and self-efficacy of 254 undergraduate psychology majors organized by 7 career intention groups (e.g., psychological research). The explanatory power of individual General Occupational Themes (GOTs), Basic Interest Scales (BISs), and Personal Style Scales (PPSs) of the Strong Interest…

  9. Pathways to Fitness for Practice: National Vocational Qualifications as a Foundation of Competence in Nurse Education.

    Science.gov (United States)

    Grundy, Lynne

    2001-01-01

    The movement in British nursing education from nursing schools to higher education has been criticized for deficiencies in skills-based training. Adding a competency-based approach using National Vocational Qualifications is a way to ensure that nurses have practical competence as well as knowledge and understanding. (Contains 24 references.) (SK)

  10. Customers' perspectives on the impact of the Pathways to Work condition management programme on their health, well-being and vocational activity.

    Science.gov (United States)

    Secker, Jenny; Pittam, Gail; Ford, Fiona

    2012-11-01

    Pathways to Work is a UK initiative aimed at supporting customers on incapacity benefits to return to work. This qualitative study complements previous evaluations of Pathways to Work by exploring customers' perceptions of the impact of the Condition Management Programme (CMP) offered to claimants with long-term health conditions. 39 customers took part in focus groups held at the seven sites where Pathways was originally piloted. The main focus of the discussions was on perceptions of the ways in which participation had impacted on health, well-being and return to work. The discussions were audio-recorded and fully transcribed for analysis using a text analysis framework to enable the development and refinement of categories and overarching patterns in the data. Perceived impacts on health and well-being included a more positive outlook, social contact, changed perceptions of conditions and improvements in health. Some customers also reported an increase in their vocational activity and others felt ready to embark on new activities. Factors associated with positive outcomes included the extent and quality of contact with CMP staff and practical advice about condition management. Factors impeding positive employment outcomes related mainly to obstacles to returning to work. The results indicated that CMP can assist customers to learn about and manage their health conditions and increase their vocational activity, and that CMP therefore provides a promising means of enabling people with long-term health conditions to regain a fulfilling, productive life.

  11. MicroRNAs to Pathways in Prostate Cancer Progression

    Science.gov (United States)

    2015-12-01

    Probasin-Cre) [38]. Analysis of resulting mice showed that deletion of Dgcr8 did not influence early epithelial hyperplasia , but severely disrupted further...dysplasia (Fig 3A). Hyperplasia was defined as tubules showing epithelial cell expansion often bridging across the lumen, whereby cells appeared... epithelial cells showed a defect in expansion of the basal epithelial , a failure to overcome Akt induced senescence, and an associated block in progression

  12. The "Girl Question" in Education: Vocational Education for Young Women in the Progressive Era. Studies in Curriculum History.

    Science.gov (United States)

    Powers, Jane Bernard

    This book analyzes the history of vocational education for girls in the United States since about 1900. The analysis is developed from the larger issues raised by what turn-of-the-century educators called "the woman question," or "What ought woman to be?" The book analyzes competing ideologies and correlates prescriptions with…

  13. Global Expression Profiling and Pathway Analysis of Mouse Mammary Tumor Reveals Strain and Stage Specific Dysregulated Pathways in Breast Cancer Progression.

    Science.gov (United States)

    Mei, Yan; Yang, Jun-Ping; Lang, Yan-Hong; Peng, Li-Xia; Yang, Ming-Ming; Liu, Qin; Meng, Dong-Fang; Zheng, Li-Sheng; Qiang, Yuan-Yuan; Xu, Liang; Li, Chang-Zhi; Wei, Wen-Wen; Niu, Ting; Peng, Xing-Si; Yang, Qin; Lin, Fen; Hu, Hao; Xu, Hong-Fa; Huang, Bi-Jun; Wang, Li-Jing; Qian, Chao-Nan

    2018-05-01

    It is believed that the alteration of tissue microenvironment would affect cancer initiation and progression. However, little is known in terms of the underlying molecular mechanisms that would affect the initiation and progression of breast cancer. In the present study, we use two murine mammary tumor models with different speeds of tumor initiation and progression for whole genome expression profiling to reveal the involved genes and signaling pathways. The pathways regulating PI3K-Akt signaling and Ras signaling were activated in Fvb mice and promoted tumor progression. Contrastingly, the pathways regulating apoptosis and cellular senescence were activated in Fvb.B6 mice and suppressed tumor progression. We identified distinct patterns of oncogenic pathways activation at different stages of breast cancer, and uncovered five oncogenic pathways that were activated in both human and mouse breast cancers. The genes and pathways discovered in our study would be useful information for other researchers and drug development.

  14. Activin pathway enhances colorectal cancer stem cell self-renew and tumor progression.

    Science.gov (United States)

    Liu, Rui; Wang, Jun-Hua; Xu, Chengxiong; Sun, Bo; Kang, Sa-Ouk

    2016-10-28

    Activin belongs to transforming growth factor (TGF)-β super family of growth and differentiation factors and activin pathway participated in broad range of cell process. Studies elaborated activin pathway maintain pluripotency in human stem cells and suggest that the function of activin/nodal signaling in self-renew would be conserved across embryonic and adult stem cells. In this study, we tried to determine the effect of activin signaling pathway in regulation of cancer stem cells as a potential target for cancer therapy in clinical trials. A population of colorectal cancer cells was selected by the treatment of activin A. This population of cell possessed stem cell character with sphere formation ability. We demonstrated activin pathway enhanced the colorectal cancer stem cells self-renew and contribute to colorectal cancer progression in vivo. Targeting activin pathway potentially provide effective strategy for colorectal cancer therapy. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. The Dutch vocational education and training system

    NARCIS (Netherlands)

    Verhagen, A.M.C.

    2014-01-01

    The Dutch educational system is highly stratified from secondary education onwards3, and this also applies to MBO. Each MBO course can be followed in two different learning pathways, called the vocationally educating learning pathway (beroepsopleidende leerweg: BOL) and the vocationally guiding

  16. Vocational Education and Vocational Skills

    DEFF Research Database (Denmark)

    Madsen, Erik Skov

    , a framework of skills related to process tasks is developed. The paper and the presentation conclude that much more focus is needed on the development of vocational education and vocational skills in Denmark, the U.K, and in the U.S. and in China for employees to be able to handle future automated......Abstract: This paper and presentation is based on case studies in China, Mexico and Denmark. The paper identifies challenges posed to production companies by a lack of vocational skills and vocational education. The study is focusing on different types of production systems i.e. on manual, complex...... and automated production. The paper highlights how both China and Denmark have focused on theoretical rather than vocational education for more than a decade. Based on a combination of a literature review and field studies of cases, including studies of mass production and unmanned and automated production...

  17. Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway

    International Nuclear Information System (INIS)

    Ma, Lijie; Dong, Pingping; Liu, Longzi; Gao, Qiang; Duan, Meng; Zhang, Si; Chen, She; Xue, Ruyi; Wang, Xiaoying

    2016-01-01

    Aberrant activation of Notch signaling frequently occurs in liver cancer, and is associated with liver malignancies. However, the mechanisms regulating pathologic Notch activation in hepatocellular carcinoma (HCC) remain unclear. Protein O-fucosyltransferase 1 (Pofut1) catalyzes the addition of O-linked fucose to the epidermal growth factor-like repeats of Notch. In the present study, we detected the expression of Pofut1 in 8 HCC cell lines and 253 human HCC tissues. We reported that Pofut1 was overexpressed in HCC cell lines and clinical HCC tissues, and Pofut1 overexpression clinically correlated with the unfavorable survival and high disease recurrence in HCC. The in vitro assay demonstrated that Pofut1 overexpression accelerated the cell proliferation and migration in HCC cells. Furthermore, Pofut1 overexpression promoted the binding of Notch ligand Dll1 to Notch receptor, and hence activated Notch signaling pathway in HCC cells, indicating that Pofut1 overexpression could be a reason for the aberrant activation of Notch signaling in HCC. Taken together, our findings indicated that an aberrant activated Pofut1-Notch pathway was involved in HCC progression, and blockage of this pathway could be a promising strategy for the therapy of HCC. - Highlights: • Pofut1 overexpression in HCC was correlated with aggressive tumor behaviors. • Pofut1 overexpression in HCC was associated with poor prognosis. • Pofut1 promoted cell proliferation, migration and invasion in hepatoma cells. • Pofut1 activated Notch signaling pathway in hepatoma cells.

  18. Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Lijie [Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai (China); Dong, Pingping [Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital of Fudan University, Shanghai (China); Liu, Longzi; Gao, Qiang; Duan, Meng [Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai (China); Zhang, Si; Chen, She [Key Laboratory of Glycoconjugate Research Ministry of Public Health, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai (China); Xue, Ruyi, E-mail: xue.ruyi@zs-hospital.sh.cn [Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital of Fudan University, Shanghai (China); Wang, Xiaoying, E-mail: xiaoyingwang@fudan.edu.cn [Liver Surgery Department, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai (China)

    2016-04-29

    Aberrant activation of Notch signaling frequently occurs in liver cancer, and is associated with liver malignancies. However, the mechanisms regulating pathologic Notch activation in hepatocellular carcinoma (HCC) remain unclear. Protein O-fucosyltransferase 1 (Pofut1) catalyzes the addition of O-linked fucose to the epidermal growth factor-like repeats of Notch. In the present study, we detected the expression of Pofut1 in 8 HCC cell lines and 253 human HCC tissues. We reported that Pofut1 was overexpressed in HCC cell lines and clinical HCC tissues, and Pofut1 overexpression clinically correlated with the unfavorable survival and high disease recurrence in HCC. The in vitro assay demonstrated that Pofut1 overexpression accelerated the cell proliferation and migration in HCC cells. Furthermore, Pofut1 overexpression promoted the binding of Notch ligand Dll1 to Notch receptor, and hence activated Notch signaling pathway in HCC cells, indicating that Pofut1 overexpression could be a reason for the aberrant activation of Notch signaling in HCC. Taken together, our findings indicated that an aberrant activated Pofut1-Notch pathway was involved in HCC progression, and blockage of this pathway could be a promising strategy for the therapy of HCC. - Highlights: • Pofut1 overexpression in HCC was correlated with aggressive tumor behaviors. • Pofut1 overexpression in HCC was associated with poor prognosis. • Pofut1 promoted cell proliferation, migration and invasion in hepatoma cells. • Pofut1 activated Notch signaling pathway in hepatoma cells.

  19. Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects

    Science.gov (United States)

    Ferraldeschi, R; Welti, J; Luo, J; Attard, G; de Bono, JS

    2015-01-01

    Androgen receptor (AR) signaling is a critical pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal treatment for patients with locally advanced and metastatic disease. However, over time, most tumors become resistant to ADT. The view of castration-resistant prostate cancer (CRPC) has changed dramatically in the last several years. Progress in understanding the disease biology and mechanisms of castration resistance led to significant advancements and to paradigm shift in the treatment. Accumulating evidence showed that prostate cancers develop adaptive mechanisms for maintaining AR signaling to allow for survival and further evolution. The aim of this review is to summarize molecular mechanisms of castration resistance and provide an update in the development of novel agents and strategies to more effectively target the AR signaling pathway. PMID:24837363

  20. The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression.

    Science.gov (United States)

    Dupouy, Sandra; Viardot-Foucault, Véronique; Alifano, Marco; Souazé, Frédérique; Plu-Bureau, Geneviève; Chaouat, Marc; Lavaur, Anne; Hugol, Danielle; Gespach, Christian; Gompel, Anne; Forgez, Patricia

    2009-01-01

    The neurotensin (NTS) and its specific high affinity G protein coupled receptor, the NT1 receptor (NTSR1), are considered to be a good candidate for one of the factors implicated in neoplastic progression. In breast cancer cells, functionally expressed NT1 receptor coordinates a series of transforming functions including cellular migration and invasion. we investigated the expression of NTS and NTSR1 in normal human breast tissue and in invasive ductal breast carcinomas (IDCs) by immunohistochemistry and RT-PCR. NTS is expressed and up-regulated by estrogen in normal epithelial breast cells. NTS is also found expressed in the ductal and invasive components of IDCs. The high expression of NTSR1 is associated with the SBR grade, the size of the tumor, and the number of metastatic lymph nodes. Furthermore, the NTSR1 high expression is an independent factor of prognosis associated with the death of patients. these data support the activation of neurotensinergic deleterious pathways in breast cancer progression.

  1. Targeting Glutamatergic Signaling and the PI3 Kinase Pathway to Halt Melanoma Progression

    Directory of Open Access Journals (Sweden)

    Stephen A. Rosenberg

    2015-02-01

    Full Text Available Our group has previously reported that the majority of human melanomas (>60% express the metabotropic glutamate receptor 1 (GRM1 and that the glutamate release inhibitor riluzole, a drug currently used to treat amyotrophic lateral sclerosis, can induce apoptosis in GRM1-expressing melanoma cells. Our group previously reported that in vitro riluzole treatment reduces cell growth in three-dimensional (3D soft agar colony assays by 80% in cells with wildtype phosphoinositide 3-kinase (PI3K pathway activation. However, melanoma cell lines harboring constitutive activating mutations of the PI3K pathway (PTEN and NRAS mutations showed only a 35% to 40% decrease in colony formation in soft agar in the presence of riluzole. In this study, we have continued our preclinical studies of riluzole and its effect on melanoma cells alone and in combination with inhibitors of the PI3 kinase pathway: the AKT inhibitor, API-2, and the mammalian target of rapamycin (mTOR inhibitor, rapamycin. We modeled these combinatorial therapies on various melanoma cell lines in 3D and 2D systems and in vivo. Riluzole combined with mTOR inhibition is more effective at halting melanoma anchorage-independent growth and xenograft tumor progression than either agent alone. PI3K signaling changes associated with this combinatorial treatment shows that 3D (nanoculture modeling of cell signaling more closely resembles in vivo signaling than monolayer models. Riluzole combined with mTOR inhibition is effective at halting tumor cell progression independent of BRAF mutational status. This makes this combinatorial therapy a potentially viable alternative for metastatic melanoma patients who are BRAF WT and are therefore ineligible for vemurafenib therapy.

  2. Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA.

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    Yin, Li; Cai, Zhihui; Zhu, Baoan; Xu, Cunshuan

    2018-02-14

    Hepatocellular carcinoma (HCC) is a devastating disease worldwide. Though many efforts have been made to elucidate the process of HCC, its molecular mechanisms of development remain elusive due to its complexity. To explore the stepwise carcinogenic process from pre-neoplastic lesions to the end stage of HCC, we employed weighted gene co-expression network analysis (WGCNA) which has been proved to be an effective method in many diseases to detect co-expressed modules and hub genes using eight pathological stages including normal, cirrhosis without HCC, cirrhosis, low-grade dysplastic, high-grade dysplastic, very early and early, advanced HCC and very advanced HCC. Among the eight consecutive pathological stages, five representative modules are selected to perform canonical pathway enrichment and upstream regulator analysis by using ingenuity pathway analysis (IPA) software. We found that cell cycle related biological processes were activated at four neoplastic stages, and the degree of activation of the cell cycle corresponded to the deterioration degree of HCC. The orange and yellow modules enriched in energy metabolism, especially oxidative metabolism, and the expression value of the genes decreased only at four neoplastic stages. The brown module, enriched in protein ubiquitination and ephrin receptor signaling pathways, correlated mainly with the very early stage of HCC. The darkred module, enriched in hepatic fibrosis/hepatic stellate cell activation, correlated with the cirrhotic stage only. The high degree hub genes were identified based on the protein-protein interaction (PPI) network and were verified by Kaplan-Meier survival analysis. The novel five high degree hub genes signature that was identified in our study may shed light on future prognostic and therapeutic approaches. Our study brings a new perspective to the understanding of the key pathways and genes in the dynamic changes of HCC progression. These findings shed light on further investigations.

  3. Who attracts whom to rural general practice? Variation in temperament and character profiles of GP registrars across different vocational training pathways.

    Science.gov (United States)

    Eley, Diann S; Laurence, Caroline; Cloninger, C R; Walters, Lucie

    2015-01-01

    The ongoing rural doctor workforce shortage continues to stimulate interest in new strategies to alleviate the situation. Alongside increasingly promising approaches is the notion that attracting and nurturing the 'right' individuals may be paramount to achieving long-term success in recruitment and retention. This study compares the patterns of demographic and temperament and character trait profiles of general practice registrars in training across three Australian vocational training pathways: the Australian College of Rural and Remote Medicine independent rural pathway, and the rural and general pathways of Australian general practice training. The aim is to describe the predominant personalities of existing trainees. At its foundation, this study strives to obtain more information about those individuals choosing rural practice, which may inform ways to enhance future recruitment and training into rural medicine. This rationale has been explored with medical students using intention as the dependent variable, but registrars are that much closer to their final career choice, and therefore may provide more practical and reliable indicators of the notion of who attracts whom into rural practice. A cross-sectional design sampled four registrar training groups: one from the Australian College of Rural and Remote Medicine, one Australian general practice training rural only, and two Australian general practice training rural and general pathway regional training providers. Registrars (451) completed a questionnaire that gathered basic demographics and a personality trait profile using the Temperament and Character Inventory plus a measure of resilience. Statistical analysis explored the relationships between variables (multivariate analyses of variance) and compared levels of traits between registrar groups (analyses of variance). Registrars training via the Australian College of Rural and Remote Medicine pathway were more likely to be male, older, have a definite

  4. Relationship of COP System Interest Inventory Scales to Vocational Preference Inventory (VPI) Scales in a College Sample: Construct Validity of Scales Based on Progressed Occupational Interest.

    Science.gov (United States)

    Omizo, Michael M.; And Others

    1983-01-01

    Construct validity data found some support for the California Occupational Preference System constructs when its results were evaluated on a sample of 213 female undergraduates relative to the Vocational Preference Inventory results. (PN)

  5. Visual pathway function and structure in Wolfram syndrome: patient age, variation and progression.

    Science.gov (United States)

    Hoekel, James; Narayanan, Anagha; Rutlin, Jerrel; Lugar, Heather; Al-Lozi, Amal; Hershey, Tamara; Tychsen, Lawrence

    2018-01-01

    To report alterations in visual acuity and visual pathway structure over an interval of 1-3 years in a cohort of children, adolescents and young adults who have Wolfram syndrome (WFS) and to describe the range of disease severity evident in patients with WFS whose ages differed by as much as 20 years at first examination. Annual, prospective ophthalmological examinations were performed in conjunction with retinal nerve fibre layer (RNFL) analysis. Diffusion tensor MRI-derived fractional anisotropy was used to assess the microstructural integrity of the optic radiations (OR FA). Mean age of the 23 patients with WFS in the study was 13.8 years (range 5-25 years). Mean log minimum angle resolution visual acuity was 0.66 (20/91). RNFL thickness was subnormal in even the youngest patients with WFS. Average RNFL thickness in patients with WFS was 57±8 µ or ~40% thinner than that measured in normal (94±10 µ) children and adolescents (P<0.01). Lower OR FA correlated with worse visual acuity (P=0.006). Subsequent examinations showed declines (P<0.05) in visual acuity, RNFL thickness and OR FA at follow-up intervals of 12-36 months. However, a wide range of disease severity was evident across ages: some of the youngest patients at their first examination had deficits more severe than the oldest patients. The genetic mutation of WFS causes damage to both pregeniculate and postgeniculate regions of the visual pathway. The damage is progressive. The decline in visual pathway structure is accompanied by declines of visual function. Disease severity differs widely in individual patients and cannot be predicted from their age.

  6. The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression.

    Directory of Open Access Journals (Sweden)

    Sandra Dupouy

    Full Text Available BACKGROUND: The neurotensin (NTS and its specific high affinity G protein coupled receptor, the NT1 receptor (NTSR1, are considered to be a good candidate for one of the factors implicated in neoplastic progression. In breast cancer cells, functionally expressed NT1 receptor coordinates a series of transforming functions including cellular migration and invasion. METHODS AND RESULTS: we investigated the expression of NTS and NTSR1 in normal human breast tissue and in invasive ductal breast carcinomas (IDCs by immunohistochemistry and RT-PCR. NTS is expressed and up-regulated by estrogen in normal epithelial breast cells. NTS is also found expressed in the ductal and invasive components of IDCs. The high expression of NTSR1 is associated with the SBR grade, the size of the tumor, and the number of metastatic lymph nodes. Furthermore, the NTSR1 high expression is an independent factor of prognosis associated with the death of patients. CONCLUSION: these data support the activation of neurotensinergic deleterious pathways in breast cancer progression.

  7. AS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: regulation of the AKT downstream pathway.

    Directory of Open Access Journals (Sweden)

    Itay Israel Shemesh

    Full Text Available Diabetic nephropathy (DN is characterized by proliferation of mesangial cells, mesangial expansion, hypertrophy and extracellular matrix accumulation. Previous data have cross-linked PKB (AKT to TGFβ induced matrix modulation. The non-toxic compound AS101 has been previously shown to favorably affect renal pathology in various animal models and inhibits AKT activity in leukemic cells. Here, we studied the pharmacological properties of AS101 against the progression of rat DN and high glucose-induced mesangial dysfunction. In-vivo administration of AS101 to Streptozotocin injected rats didn't decreased blood glucose levels but ameliorated kidney hypotrophy, proteinuria and albuminuria and downregulated cortical kidney phosphorylation of AKT, GSK3β and SMAD3. AS101 treatment of primary rat glomerular mesangial cells treated with high glucose significantly reduced their elevated proliferative ability, as assessed by XTT assay and cell cycle analysis. This reduction was associated with decreased levels of p-AKT, increased levels of PTEN and decreased p-GSK3β and p-FoxO3a expression. Pharmacological inhibition of PI3K, mTORC1 and SMAD3 decreased HG-induced collagen accumulation, while inhibition of GSK3β did not affect its elevated levels. AS101 also prevented HG-induced cell growth correlated to mTOR and (rpS6 de-phosphorylation. Thus, pharmacological inhibition of the AKT downstream pathway by AS101 has clinical potential in alleviating the progression of diabetic nephropathy.

  8. Assessment of Food Chain Pathway Parameters in Biosphere Models: Annual Progress Report for Fiscal Year 2004

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    Napier, Bruce A.; Krupka, Kenneth M.; Fellows, Robert J.; Cataldo, Dominic A.; Valenta, Michelle M.; Gilmore, Tyler J.

    2004-12-02

    This Annual Progress Report describes the work performed and summarizes some of the key observations to date on the U.S. Nuclear Regulatory Commission’s project Assessment of Food Chain Pathway Parameters in Biosphere Models, which was established to assess and evaluate a number of key parameters used in the food-chain models used in performance assessments of radioactive waste disposal facilities. Section 2 of this report describes activities undertaken to collect samples of soils from three regions of the United States, the Southeast, Northwest, and Southwest, and perform analyses to characterize their physical and chemical properties. Section 3 summarizes information gathered regarding agricultural practices and common and unusual crops grown in each of these three areas. Section 4 describes progress in studying radionuclide uptake in several representative crops from the three soil types in controlled laboratory conditions. Section 5 describes a range of international coordination activities undertaken by Project staff in order to support the underlying data needs of the Project. Section 6 provides a very brief summary of the status of the GENII Version 2 computer program, which is a “client” of the types of data being generated by the Project, and for which the Project will be providing training to the US NRC staff in the coming Fiscal Year. Several appendices provide additional supporting information.

  9. Intersections of pathways involving biotin and iron relative to therapeutic mechanisms for progressive multiple sclerosis.

    Science.gov (United States)

    Heidker, Rebecca M; Emerson, Mitchell R; LeVine, Steven M

    2016-12-01

    While there are a variety of therapies for relapsing remitting multiple sclerosis (MS), there is a lack of treatments for progressive MS. An early study indicated that high dose biotin therapy has beneficial effects in approximately 12-15% of patients with progressive MS. The mechanisms behind the putative improvements seen with biotin therapy are not well understood, but have been postulated to include: 1) improving mitochondrial function which is impaired in MS, 2) increasing synthesis of lipids and cholesterol to facilitate remyelination, and 3) affecting gene expression. We suggest one reason that a greater percentage of patients with MS didn't respond to biotin therapy is the inaccessibility or lack of other nutrients, such as iron. In addition to biotin, iron (or heme) is necessary for energy production, biosynthesis of cholesterol and lipids, and for some protective mechanisms. Both biotin and iron are required for myelination during development, and by inference, remyelination. However, iron can also play a role in the pathology of MS. Increased deposition of iron can occur in some CNS structures possibly promoting oxidative damage while low iron levels can occur in other areas. Thus, the potential, detrimental effects of iron need to be considered together with the need for iron to support metabolic demands associated with repair and/or protective processes. We propose the optimal utilization of iron may be necessary to maximize the beneficial effects of biotin. This review will examine the interactions between biotin and iron in pathways that may have therapeutic or pathogenic implications for MS.

  10. CXCL-8 Regulates Head and Neck Carcinoma Progression through NOD Signalling Pathway

    Directory of Open Access Journals (Sweden)

    Chan Leong-Perng

    2017-01-01

    Full Text Available Head and neck squamous cell carcinoma (HNSCC ranks sixth among the most common cancers in the world. Interlukin-8 (CXCL-8, a major role in inflammatory response and tumor microenvironment, correlates with tumor progression, metastasis and invasion. We explored CXCL-8 promotes tumor progression in different differentiation HNSCC cells. This project would apply to development on biomarker and target in HNSCC as well as provide a basis of early diagnosis and treatment for clinical. CXCL-8, NOD1 (nucleotide-binding oligomerization domain-containing protein 1 and receptor-interacting protein kinase (RIPK2 levels were detected statistically higher in patient tissue with HNSCC than in non-cancerous matched tissue (NCMT in the microarray and qRT-PCR study, whereas NOD2 was weakly expressed. Similar results were obtained for CXCL-8, NOD1, NOD2 and RIP2 from RT-PCR and western blotting. High CXCL-8, NOD1 and RIP2 expressions were found on HNSCC patient tissue than that of NCMT, whereas NOD2 was weakly expressed. The analytical results indicate that CXCL-8 is required in NOD 1-mediated signalling pathways in HNSCC.

  11. Single agent vinorelbine in pediatric patients with progressive optic pathway glioma.

    Science.gov (United States)

    Cappellano, Andrea Maria; Petrilli, Antonio Sergio; da Silva, Nasjla Saba; Silva, Frederico Adolfo; Paiva, Priscila Mendes; Cavalheiro, Sergio; Bouffet, Eric

    2015-01-01

    The management of progressive unresectable low-grade glioma remains controversial. Treatment options have included radiotherapy, and more recently chemotherapy, usually following an initial period of observation. Within this context, we evaluated vinorelbine, a semi-synthetic vinca alkaloid that has shown evidence of activity against glioma. From July 2007 an institutional protocol with vinorelbine (30 mg/m(2) days 0, 8, 22) for a total of 18 cycles, has been conducted at IOP/GRAACC/UNIFESP for children with optic pathway glioma (OPG). The main objectives were clinical and radiological response, as well as toxicity profile. Twenty-three patients with progressive OPG with a mean age of 69 months (4-179) were enrolled. Three patients had a diagnosis of neurofibromatosis type 1. Twenty-two patients were assessable for response with an overall objective response rate of 63 %, with eight patients showing stable disease. The most important toxicity was hematologic (grade III/IV neutropenia) observed in four patients. Gastrointestinal toxicity (grade I/II vomiting) was observed in seven patients and only 1 patient showed grade I peripheral neuropathy. The median progression-free survival (PFS) was 33 months (6.9-69) with a 3 and 5 year PFS of 64 ± 19 and 37 ± 20 %, respectively, for an overall 3 and 5 year-survival of 95 ± 10 %. This study suggests that vinorelbine may be an interesting option for pediatric low-grade gliomas, showing low toxicity profile and providing a good quality of life for patients with such chronic disease.

  12. Dropout in vocational education

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    For the last ten years drop out of vocational education has increased strongly in Denmark. Only half of the students, who take up a vocational programme on upper secondary level, complete it. Like in other European countries the low completion rates has caused considerable alarm on the political...... level (Lamb and Markussen 2011). Continuing high dropout rates will make it very hard for the government to reach its target for educational completion, and the government has launched a series of measures to increase retention including the obligation for all colleges to make plans for retention...... and monitor the progress in achieving the goals. The questions addressed in this paper are why and how dropout in VET takes place. The objective is to provide more detailed and qualified knowledge of the complex processes of dropping out....

  13. Gene expression study and pathway analysis of histological subtypes of intestinal metaplasia that progress to gastric cancer.

    Directory of Open Access Journals (Sweden)

    Osmel Companioni

    Full Text Available Intestinal metaplasia (IM is a precursor lesion that precedes gastric cancer (GC. There are two IM histological subtypes, complete (CIM and incomplete (IIM, the latter having higher progression rates to GC. This study was aimed at analysing gene expression and molecular processes involved in the progression from normal mucosa to IM, and also from IM subtypes to GC.We used expression data to compare the transcriptome of healthy gastric mucosa to that of IM not progressing to GC, and the transcriptome of IM subtypes that had progressed to GC to those that did not progress. Some deregulated genes were validated and pathway analyses were performed.Comparison of IM subtypes that had progressed to GC with those that did not progress showed smaller differences in the expression profiles than the comparison of IM that did not progress with healthy mucosa. New transcripts identified in IM not progressing to GC included TRIM, TMEM, homeobox and transporter genes and SNORD116. Comparison to normal mucosa identified non tumoral Warburg effect and melatonin degradation as previously unreported processes involved in IM. Overexpressed antigen processing is common to both IM-subtypes progressing to GC, but IIM showed more over-expressed oncogenic genes and molecular processes than CIM.There are greater differences in gene expression and molecular processes involved in the progression from normal healthy mucosa to IM than from IM to gastric cancer. While antigen processing is common in both IM-subtypes progressing to GC, more oncogenic processes are observed in the progression of IIM.

  14. Vocational Teachers and Professionalism

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Duch, Henriette

    as other contextual factors. Our concern is adult vocational teachers attending a pedagogical course and teaching at vocational colleges. The aim of the paper is to discuss different models and develop a model concerning teachers at vocational colleges based on empirical data in a specific context......, vocational teacher-training course in Denmark. By offering a basis and concepts for analysis of practice such model is meant to support the development of vocational teachers’ professionalism at courses and in organizational contexts in general....

  15. The regulation effect of STAT 5 signaling pathway on the cell cycle progression of irradiated KG-1 cells

    International Nuclear Information System (INIS)

    Guo Dehuang; Dong Bo; Luo Qingliang; Wen Gengyun; Mao Bingzhi

    2000-01-01

    The author investigated the role of the JAK/STAT signaling pathway regulating cell cycle progression in the irradiated KG-1 cells. By permanent transfecting the cells with DN-STAT 5 cDNA to block the JAK/STAT signaling pathway and then transient transfecting with cyclin D 1 or cyclin B 1 cDNA, the effects of cyclin D 1 protein and cyclin B 1 protein on the cell cycle progression were examined. Results showed that after irradiation with 8Gy 60 Co rays, the irradiated KG-1 cells transfected with only DN-STAT 5 cDNA can not recover form the G 1 arrest, even though GM-CSF was added. Meanwhile, the cells transfected with both the DN-STAT 5 cDNA and cyclin D 1 cDNA or cyclin B 1 cDNA can recover from the G 1 arrest or the G 2 arrest to a great extent. Thus, it was proved indirectly that the JAK/STAT signaling pathway activated by GM-CSF regulated the cell cycle progression through cyclin D 1 and cyclin B 1 protein

  16. The Internal and External Factors of Vocational Path Choice

    OpenAIRE

    Urbanavičiūtė, Ieva

    2010-01-01

    The main objective of the doctoral thesis was to analyze the features of one’s vocational path during the time of undergraduate studies. Undergraduate studies can be treated as a pathway of transition from school to the world of work. Therefore, it is especially important to identify what makes vocational choice successful during this period of time. In the study, several psychological success indicators of vocational path choice were distinguished. Moreover, the following factors were analyz...

  17. More work to do: a pathway for future progress on strengthening nuclear security

    NARCIS (Netherlands)

    Herbach, J.; Pitts-Kiefer, S.

    2015-01-01

    With the nuclear security summit process winding down but much work remaining, it is vital to initiate a process by which states can continue and expand on the substantial progress that already has been made.

  18. [Cinema and professional vocation].

    Science.gov (United States)

    García Sánchez, José Elías

    2011-01-01

    Commercial cinema is both narrative art and a widely-used mass medium that is built upon human stories. Among the contents of these stories there are many vocational aspects. Taking advantage of these circumstances we will proceed to analyze health vocations through eight films. Patch Adams allows us to approach the fulfillment of vocation, which has not been an easy task for women, as we can see in Allá en el setenta y tantos. Vocational fulfillment is at the core of the plot in The Citadel. Something the Lord Made is a good example to illustrate an unfulfilled vocation, in the same way as Awakenings and Arrowsmith represent the fulfillment of an unexpected vocation and a long pursued one. Finally, vocation can demand great sacrifices, which is made crystal clear in Korczak, and when vocation is not strictly followed it might lead to the greatest abominations, which is the case in "The Fugitive. "

  19. Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.

    Science.gov (United States)

    Galamb, Orsolya; Kalmár, Alexandra; Péterfia, Bálint; Csabai, István; Bodor, András; Ribli, Dezső; Krenács, Tibor; Patai, Árpád V; Wichmann, Barnabás; Barták, Barbara Kinga; Tóth, Kinga; Valcz, Gábor; Spisák, Sándor; Tulassay, Zsolt; Molnár, Béla

    2016-08-02

    The WNT signaling pathway has an essential role in colorectal carcinogenesis and progression, which involves a cascade of genetic and epigenetic changes. We aimed to analyze DNA methylation affecting the WNT pathway genes in colorectal carcinogenesis in promoter and gene body regions using whole methylome analysis in 9 colorectal cancer, 15 adenoma, and 6 normal tumor adjacent tissue (NAT) samples by methyl capture sequencing. Functional methylation was confirmed on 5-aza-2'-deoxycytidine-treated colorectal cancer cell line datasets. In parallel with the DNA methylation analysis, mutations of WNT pathway genes (APC, β-catenin/CTNNB1) were analyzed by 454 sequencing on GS Junior platform. Most differentially methylated CpG sites were localized in gene body regions (95% of WNT pathway genes). In the promoter regions, 33 of the 160 analyzed WNT pathway genes were differentially methylated in colorectal cancer vs. normal, including hypermethylated AXIN2, CHP1, PRICKLE1, SFRP1, SFRP2, SOX17, and hypomethylated CACYBP, CTNNB1, MYC; 44 genes in adenoma vs. NAT; and 41 genes in colorectal cancer vs. adenoma comparisons. Hypermethylation of AXIN2, DKK1, VANGL1, and WNT5A gene promoters was higher, while those of SOX17, PRICKLE1, DAAM2, and MYC was lower in colon carcinoma compared to adenoma. Inverse correlation between expression and methylation was confirmed in 23 genes, including APC, CHP1, PRICKLE1, PSEN1, and SFRP1. Differential methylation affected both canonical and noncanonical WNT pathway genes in colorectal normal-adenoma-carcinoma sequence. Aberrant DNA methylation appears already in adenomas as an early event of colorectal carcinogenesis.

  20. The Regulation of the Angiogenic Factor FGF Binding Protein (FGF-BP) by the APC/Beta-Catenin Signaling Pathway in the Progression of Breast Cancer

    National Research Council Canada - National Science Library

    Stylianou, Dora

    2004-01-01

    ...) to study the expression of FGF-BP in mammary tumorigenesis progression of the APC/+ mouse and 2) to determine the mechanism of regulation of FGF-BP b the APC/beta-catenin signaling pathway in breast cancer...

  1. The Regulation of the Angiogenic Factor FGF Binding Protein (FGF-BP) by the APC/Beta-Catenin Signaling Pathway in the Progression of Breast Cancer

    National Research Council Canada - National Science Library

    Stylianou, Dora

    2003-01-01

    ...) to study the expression of FGF-BP in mammary tumorigenesis% progression of the APC/+ mouse and 2) to determine the mechanism of regulation of FGF-BP by the APC/beta- catenin signaling pathway in breast cancer...

  2. Vocational Education and Vocational Skills in Production

    DEFF Research Database (Denmark)

    Madsen, Erik Skov

    2015-01-01

    Through case studies in China, Mexico and Denmark, this paper identifies challenges posed to production companies by a lack of vocational skills and vocational education. The study includes manual, complex and automated production procedures. The paper highlights how both China and Denmark have...... focused on theoretical rather than vocational education for more than a decade. Based on a combination of a literature review and field studies of cases, including studies of mass production and unmanned and automated production, a framework of skills related to process tasks is developed. The paper...... concludes that much more focus on the development of vocational education and vocational skills is needed in Denmark, the U.K, the U.S. and in China for employees to be equipped to handle future automated and advanced production systems....

  3. Vocational teacher education and vocational didactics

    DEFF Research Database (Denmark)

    Duch, Henriette

    2017-01-01

    .e., the same type of issues that newly enrolled students at the vocational college are facing. Our article is based on empirical data from a long-term, qualitative study of the Diploma of Vocational Pedagogy programme. It examines the learning trajectories of vocational teachers who choose to come back as VET...... their pedagogical education as teachers, i.e., transitional coherence, are not the same. The empirical data from the cases were collected via qualitative and ethnography-inspired methods, i.e., observations, focus group interviews, interviews and analyses of diploma projects from the programme......., vocational field at a specific type of college. Due to these factors, the individual teachers will experience different ‘learning trajectories’ (Lave, 2011), depending on vocational field and place of employment. They will gather different experiences, including the experience of going back to school, i...

  4. Research progress in the radioprotective effect of the canonical Wnt pathway

    International Nuclear Information System (INIS)

    Wang, Jin-Feng; Liu, Chao; Zhang, Qu; Huang, Guan-Hong

    2013-01-01

    Irradiation from diverse sources is ubiquitous and closely associated with human activities. Radiation therapy (RT), an important component of multiple radiation origins, is a common therapeutic modality for cancer. More importantly, RT provides significant contribution to oncotherapy by killing tumor cells. However, during the course of therapy, irradiation of normal tissues can result in a wide range of side effects, including self-limited acute toxicities, mild chronic symptoms, or severe organ dysfunction. Although numerous promising radioprotective agents have emerged, only a few have successfully entered the market because of various limitations. At present, the widely accepted hypothesis for protection against radiation-caused injury involves the Wnt canonical pathway. Activating the Wnt/β-catenin signaling pathway may protect the salivary gland, oral mucosa, and gastrointestinal epithelium from radiation damage. The underlying mechanisms include inhibiting apoptosis and preserving normal tissue functions. However, aberrant Wnt signaling underlies a wide range of pathologies in humans, and its various components contribute to cancer. Moreover, studies have suggested that Wnt/β-catenin signaling may lead to radioresistance of cancer stem cell. These facts markedly complicate any definition of the exact function of the Wnt pathway

  5. Early Dysregulation of Cell Adhesion and Extracellular Matrix Pathways in Breast Cancer Progression

    Science.gov (United States)

    Emery, Lyndsey A.; Tripathi, Anusri; King, Chialin; Kavanah, Maureen; Mendez, Jane; Stone, Michael D.; de las Morenas, Antonio; Sebastiani, Paola; Rosenberg, Carol L.

    2009-01-01

    Proliferative breast lesions, such as simple ductal hyperplasia (SH) and atypical ductal hyperplasia (ADH), are candidate precursors to ductal carcinoma in situ (DCIS) and invasive cancer. To better understand the relationship of breast lesions to more advanced disease, we used microdissection and DNA microarrays to profile the gene expression of patient-matched histologically normal (HN), ADH, and DCIS from 12 patients with estrogen receptor positive sporadic breast cancer. SH were profiled from a subset of cases. We found 837 differentially expressed genes between DCIS-HN and 447 between ADH-HN, with >90% of the ADH-HN genes also present among the DCIS-HN genes. Only 61 genes were identified between ADH-DCIS. Expression differences were reproduced in an independent cohort of patient-matched lesions by quantitative real-time PCR. Many breast cancer-related genes and pathways were dysregulated in ADH and maintained in DCIS. Particularly, cell adhesion and extracellular matrix interactions were overrepresented. Focal adhesion was the top pathway in each gene set. We conclude that ADH and DCIS share highly similar gene expression and are distinct from HN. In contrast, SH appear more similar to HN. These data provide genetic evidence that ADH (but not SH) are often precursors to cancer and suggest cancer-related genetic changes, particularly adhesion and extracellular matrix pathways, are dysregulated before invasion and even before malignancy is apparent. These findings could lead to novel risk stratification, prevention, and treatment approaches. PMID:19700746

  6. The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

    Science.gov (United States)

    He, Chunbo; Mao, Dagan; Hua, Guohua; Lv, Xiangmin; Chen, Xingcheng; Angeletti, Peter C; Dong, Jixin; Remmenga, Steven W; Rodabaugh, Kerry J; Zhou, Jin; Lambert, Paul F; Yang, Peixin; Davis, John S; Wang, Cheng

    2015-01-01

    The Hippo signaling pathway controls organ size and tumorigenesis through a kinase cascade that inactivates Yes-associated protein (YAP). Here, we show that YAP plays a central role in controlling the progression of cervical cancer. Our results suggest that YAP expression is associated with a poor prognosis for cervical cancer. TGF-α and amphiregulin (AREG), via EGFR, inhibit the Hippo signaling pathway and activate YAP to induce cervical cancer cell proliferation and migration. Activated YAP allows for up-regulation of TGF-α, AREG, and EGFR, forming a positive signaling loop to drive cervical cancer cell proliferation. HPV E6 protein, a major etiological molecule of cervical cancer, maintains high YAP protein levels in cervical cancer cells by preventing proteasome-dependent YAP degradation to drive cervical cancer cell proliferation. Results from human cervical cancer genomic databases and an accepted transgenic mouse model strongly support the clinical relevance of the discovered feed-forward signaling loop. Our study indicates that combined targeting of the Hippo and the ERBB signaling pathways represents a novel therapeutic strategy for prevention and treatment of cervical cancer. PMID:26417066

  7. Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

    Science.gov (United States)

    Guo, Yanxia; Walsh, Alice M; Canavan, Mary; Wechalekar, Mihir D; Cole, Suzanne; Yin, Xuefeng; Scott, Brittney; Loza, Mathew; Orr, Carl; McGarry, Trudy; Bombardieri, Michele; Humby, Frances; Proudman, Susanna M; Pitzalis, Costantino; Smith, Malcolm D; Friedman, Joshua R; Anderson, Ian; Madakamutil, Loui; Veale, Douglas J; Fearon, Ursula; Nagpal, Sunil

    2018-01-01

    Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown remarkable efficacy in multiple cancer types, concomitant with immune-related adverse events, including arthralgia and inflammatory arthritis (IA) in some patients. Herein, using Nivolumab (anti-PD-1 antagonist)-responsive genes along with transcriptomics of synovial tissue from multiple stages of rheumatoid arthritis (RA) disease progression, we have interrogated the activity status of PD-1 pathway during RA development. We demonstrate that the expression of PD-1 was increased in early and established RA synovial tissue compared to normal and OA synovium, whereas that of its ligands, programmed death ligand-1 (PD-L1) and PD-L2, was increased at all the stages of RA disease progression, namely arthralgia, IA/undifferentiated arthritis, early RA and established RA. Further, we show that RA patients expressed PD-1 on a majority of synovial tissue infiltrating CD4+ and CD8+ T cells. Moreover, enrichment of Nivolumab gene signature was observed in IA and RA, indicating that the PD-1 pathway was downregulated during RA disease progression. Furthermore, serum soluble (s) PD-1 levels were increased in autoantibody positive early RA patients. Interestingly, most of the early RA synovium tissue sections showed negative PD-L1 staining by immunohistochemistry. Therefore, downregulation in PD-1 inhibitory signaling in RA could be attributed to increased serum sPD-1 and decreased synovial tissue PD-L1 levels. Taken together, these data suggest that agonistic PD1 antibody-based therapeutics may show efficacy in RA treatment and interception.

  8. Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

    LENUS (Irish Health Repository)

    Guo, Yanxia

    2018-01-01

    Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown remarkable efficacy in multiple cancer types, concomitant with immune-related adverse events, including arthralgia and inflammatory arthritis (IA) in some patients. Herein, using Nivolumab (anti-PD-1 antagonist)-responsive genes along with transcriptomics of synovial tissue from multiple stages of rheumatoid arthritis (RA) disease progression, we have interrogated the activity status of PD-1 pathway during RA development. We demonstrate that the expression of PD-1 was increased in early and established RA synovial tissue compared to normal and OA synovium, whereas that of its ligands, programmed death ligand-1 (PD-L1) and PD-L2, was increased at all the stages of RA disease progression, namely arthralgia, IA\\/undifferentiated arthritis, early RA and established RA. Further, we show that RA patients expressed PD-1 on a majority of synovial tissue infiltrating CD4+ and CD8+ T cells. Moreover, enrichment of Nivolumab gene signature was observed in IA and RA, indicating that the PD-1 pathway was downregulated during RA disease progression. Furthermore, serum soluble (s) PD-1 levels were increased in autoantibody positive early RA patients. Interestingly, most of the early RA synovium tissue sections showed negative PD-L1 staining by immunohistochemistry. Therefore, downregulation in PD-1 inhibitory signaling in RA could be attributed to increased serum sPD-1 and decreased synovial tissue PD-L1 levels. Taken together, these data suggest that agonistic PD1 antibody-based therapeutics may show efficacy in RA treatment and interception.

  9. Turning the tide against cancer through sustained medical innovation: the pathway to progress.

    Science.gov (United States)

    Abernethy, Amy; Abrahams, Edward; Barker, Anna; Buetow, Ken; Burkholder, Randy; Dalton, William S; Foti, Margaret; Frueh, Felix; Gaynor, Richard B; Kean, Marcia; Khan, Zeba; Lessor, Tracy; Lichtenfeld, J Leonard; Mendelsohn, John; van't Veer, Laura

    2014-03-01

    An ever-expanding understanding of the molecular basis of the more than 200 unique diseases collectively called cancer, combined with efforts to apply these insights to clinical care, is forming the foundation of an era of personalized medicine that promises to improve cancer treatment. At the same time, these extraordinary opportunities are occurring in an environment of intense pressure to contain rising healthcare costs. This environment presents a challenge to oncology research and clinical care, because both are becoming progressively more complex and expensive, and because the current tools to measure the cost and value of advances in care (e.g., comparative effectiveness research, cost-effectiveness analysis, and health technology assessments) are not optimized for an ecosystem moving toward personalized, patient-centered care. Reconciling this tension will be essential to maintaining progress in a cost-constrained environment, especially because emerging innovations in science (e.g., increasing identification of molecular biomarkers) and in clinical process (implementation of a learning healthcare system) hold potential to dramatically improve patient care, and may ultimately help address the burden of rising costs. For example, the rapid pace of innovation taking place within oncology calls for increased capability to integrate clinical research and care to enable continuous learning, so that lessons learned from each patient treated can inform clinical decision making for the next patient. Recognizing the need to define the policies required for sustained innovation in cancer research and care in an era of cost containment, the stakeholder community must engage in an ongoing dialogue and identify areas for collaboration. This article reflects and seeks to amplify the ongoing robust discussion and diverse perspectives brought to this issue by multiple stakeholders within the cancer community, and to consider how to frame the research and regulatory

  10. Data driven linear algebraic methods for analysis of molecular pathways: application to disease progression in shock/trauma.

    Science.gov (United States)

    McGuire, Mary F; Sriram Iyengar, M; Mercer, David W

    2012-04-01

    Although trauma is the leading cause of death for those below 45years of age, there is a dearth of information about the temporal behavior of the underlying biological mechanisms in those who survive the initial trauma only to later suffer from syndromes such as multiple organ failure. Levels of serum cytokines potentially affect the clinical outcomes of trauma; understanding how cytokine levels modulate intra-cellular signaling pathways can yield insights into molecular mechanisms of disease progression and help to identify targeted therapies. However, developing such analyses is challenging since it necessitates the integration and interpretation of large amounts of heterogeneous, quantitative and qualitative data. Here we present the Pathway Semantics Algorithm (PSA), an algebraic process of node and edge analyses of evoked biological pathways over time for in silico discovery of biomedical hypotheses, using data from a prospective controlled clinical study of the role of cytokines in multiple organ failure (MOF) at a major US trauma center. A matrix algebra approach was used in both the PSA node and PSA edge analyses with different matrix configurations and computations based on the biomedical questions to be examined. In the edge analysis, a percentage measure of crosstalk called XTALK was also developed to assess cross-pathway interference. In the node/molecular analysis of the first 24h from trauma, PSA uncovered seven molecules evoked computationally that differentiated outcomes of MOF or non-MOF (NMOF), of which three molecules had not been previously associated with any shock/trauma syndrome. In the edge/molecular interaction analysis, PSA examined four categories of functional molecular interaction relationships--activation, expression, inhibition, and transcription--and found that the interaction patterns and crosstalk changed over time and outcome. The PSA edge analysis suggests that a diagnosis, prognosis or therapy based on molecular interaction

  11. M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis.

    Directory of Open Access Journals (Sweden)

    He Zhou

    Full Text Available Heparan sulfate proteoglycans (HSPGs play a key role in shaping the tumor microenvironment by presenting growth factors, cytokines, and other soluble factors that are critical for host cell recruitment and activation, as well as promoting tumor progression, metastasis, and survival. M402 is a rationally engineered, non-cytotoxic heparan sulfate (HS mimetic, designed to inhibit multiple factors implicated in tumor-host cell interactions, including VEGF, FGF2, SDF-1α, P-selectin, and heparanase. A single s.c. dose of M402 effectively inhibited seeding of B16F10 murine melanoma cells to the lung in an experimental metastasis model. Fluorescent-labeled M402 demonstrated selective accumulation in the primary tumor. Immunohistological analyses of the primary tumor revealed a decrease in microvessel density in M402 treated animals, suggesting anti-angiogenesis to be one of the mechanisms involved in-vivo. M402 treatment also normalized circulating levels of myeloid derived suppressor cells in tumor bearing mice. Chronic administration of M402, alone or in combination with cisplatin or docetaxel, inhibited spontaneous metastasis and prolonged survival in an orthotopic 4T1 murine mammary carcinoma model. These data demonstrate that modulating HSPG biology represents a novel approach to target multiple factors involved in tumor progression and metastasis.

  12. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression.

    Science.gov (United States)

    Schrecengost, Randy S; Dean, Jeffry L; Goodwin, Jonathan F; Schiewer, Matthew J; Urban, Mark W; Stanek, Timothy J; Sussman, Robyn T; Hicks, Jessica L; Birbe, Ruth C; Draganova-Tacheva, Rossitza A; Visakorpi, Tapio; DeMarzo, Angelo M; McMahon, Steven B; Knudsen, Karen E

    2014-01-01

    Increasing evidence links deregulation of the ubiquitin-specific proteases 22 (USP22) deubitiquitylase to cancer development and progression in a select group of tumor types, but its specificity and underlying mechanisms of action are not well defined. Here we show that USP22 is a critical promoter of lethal tumor phenotypes that acts by modulating nuclear receptor and oncogenic signaling. In multiple xenograft models of human cancer, modeling of tumor-associated USP22 deregulation demonstrated that USP22 controls androgen receptor accumulation and signaling, and that it enhances expression of critical target genes coregulated by androgen receptor and MYC. USP22 not only reprogrammed androgen receptor function, but was sufficient to induce the transition to therapeutic resistance. Notably, in vivo depletion experiments revealed that USP22 is critical to maintain phenotypes associated with end-stage disease. This was a significant finding given clinical evidence that USP22 is highly deregulated in tumors, which have achieved therapeutic resistance. Taken together, our findings define USP22 as a critical effector of tumor progression, which drives lethal phenotypes, rationalizing this enzyme as an appealing therapeutic target to treat advanced disease.

  13. The Analysis on Emotional Education in Vocational School English Teaching

    Institute of Scientific and Technical Information of China (English)

    兰州职业技术学院 730070

    2015-01-01

    In the time of advancing quality education, emotion education has been paid more and more attention. English teaching is both language teaching progress and emotional communication progress. Therefore, emotional education is extremely important and indispensable in vocational school classroom teaching. However, the current application of vocational school emotional education in English classroom teaching is still relatively weak. Based on the theory of emotional education, this paper attempts to explore the methods and strategies of applying emotional education in vocational school English classroom teaching. It has important theoretical significance on promoting the comprehensive development of the vocational school students, improving English teaching effect, promoting the healthy and sustainable development of the vocational school education, and enriching and developing the emotional teaching psychology and cognitive psychology theory.

  14. Bioenergetic coupling between membrane transport systems and biosynthetic pathways essential for cell cycle progression

    International Nuclear Information System (INIS)

    Leister, K.J.; Cutry, A.F.; Wenner, C.E.

    1986-01-01

    Recently, it has been shown that there exists a point in the cell cycle (approximately 2 h prior to S phase entry) when (Na + /K + )ATPase pump activity is no longer needed for progression through the cycle. These data suggests that pump activity is critical in the biosynthetic processes which enables the cell to proceed through the G 1 phase. A scheme is proposed which is currently being tested that (Na + /K + )ATPase pump activity serves as the driving force in the regulation of other membrane transport processes critical for cell proliferation. For example, in post-confluent quiescent C3H-10T1/2 fibroblasts, when [K + ]/sub o/ is lowered just below the K/sub m/ of the pump for K + there is a 10-fold increase in 3 H-uridine uptake into both acid soluble and insoluble cell fractions. By modulation of the pump in this manner, glucose utilization is enhanced whereas inhibition of the pump by ouabain suppresses glucose utilization. In both methods of affecting the pump, 3 H-leucine incorporation is inhibited. Electron acceptors that influence the redox state of the cell have been shown to both stimulate or inhibit cell cycle progression. Under conditions where [K + ]/sub o/ is lowered, the nucleoside uptake responses observed were modified by electron acceptors depending on the ability to oxidize NAD(P)H directly or to interact with a cytochrome-like component, (e.g. phenazine methosulfate) reversed the enhanced uridine uptake and p-phenylene diamine further enhanced the uridine uptake response. These findings suggest that a plasma membrane redox system (presumably cyt-c like) is linked to nucleoside transport which is subject to (Na + /K + )ATPase activity

  15. Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors

    International Nuclear Information System (INIS)

    Zhang, Ge; Miyake, Makito; Lawton, Adrienne; Goodison, Steve; Rosser, Charles J

    2014-01-01

    Cancer invasion and metastasis develops through a series of steps that involve the loss of cell to cell and cell to matrix adhesion, degradation of extracellular matrix and induction of angiogenesis. Different protease systems (e.g., matrix metalloproteinases, MMPs) are involved in these steps. MMP-10, one of the lesser studied MMPs, is limited to epithelial cells and can facilitate tumor cell invasion by targeting collagen, elastin and laminin. Enhanced MMP-10 expression has been linked to poor clinical prognosis in some cancers, however, mechanisms underlying a role for MMP-10 in tumorigenesis and progression remain largely unknown. Here, we report that MMP-10 expression is positively correlated with the invasiveness of human cervical and bladder cancers. Using commercial tissue microarray (TMA) of cervical and bladder tissues, MMP-10 immunohistochemical staining was performed. Furthermore using a panel of human cells (HeLa and UROtsa), in vitro and in vivo experiments were performed in which MMP-10 was overexpressed or silenced and we noted phenotypic and genotypic changes. Experimentally, we showed that MMP-10 can regulate tumor cell migration and invasion, and endothelial cell tube formation, and that MMP-10 effects are associated with a resistance to apoptosis. Further investigation revealed that increasing MMP-10 expression stimulates the expression of HIF-1α and MMP-2 (pro-angiogenic factors) and PAI-1 and CXCR2 (pro-metastatic factors), and accordingly, targeting MMP-10 with siRNA in vivo resulted in diminution of xenograft tumor growth with a concomitant reduction of angiogenesis and a stimulation of apoptosis. Taken together, our findings show that MMP-10 can play a significant role in tumor growth and progression, and that MMP-10 perturbation may represent a rational strategy for cancer treatment

  16. VOCATIONAL INTEREST, COUNSELLING, SOCIO- ECONOMIC ...

    African Journals Online (AJOL)

    Elizabeth

    The aim of the study was to investigate the relationship between vocational ... Modified Bakare Vocational interest inventory, the instrument on counselling, .... family influences the vocational preference of youths. .... Theories of Personality.

  17. Gene expression disorders of innate antibacterial signaling pathway in pancreatic cancer patients: implications for leukocyte dysfunction and tumor progression

    Science.gov (United States)

    Dąbrowska, Aleksandra; Lech, Gustaw; Słodkowski, Maciej; Słotwińska, Sylwia M.

    2014-01-01

    The study was carried out to investigate changes in gene expression of innate antibacterial signaling pathways in patients with pancreatic cancer. Expression of the following genes was measured in peripheral blood leukocytes of 55 patients with pancreatic adenocarcinoma using real-time polymerase chain reaction (RT-PCR): TLR4, NOD1, MyD88, TRAF6 and HMGB1. The levels of expression of TLR4, NOD1 and TRAF6 genes were significantly elevated (p = 0.007; p = 0.001 and p = 0.01, respectively), while MyD88 expression was markedly reduced (p = 0.0002), as compared to controls. Expression of TLR4 and NOD1 exceeded the normal level more than 3.5-fold and there was a significant correlation found between the expression of these genes (r = 0.558, p < 0.001). TLR4, NOD1 and MyD88 genes were expressed at a similar level both before and after surgery. No significant changes in the expression of HMGB1 gene were observed. The results of the study clearly indicate abnormal expression of genes belonging to innate antibacterial signaling pathways in peripheral blood leukocytes of patients with pancreatic cancer, which may lead to leukocyte dysfunction. Overexpression of TLR4, NOD1 and TRAF6 genes, and decreased MyD88 gene expression may contribute to chronic inflammation and tumor progression by up-regulation of the innate antibacterial response. The parameters tested are useful for monitoring innate immunity gene disorders and pancreatic cancer progression. PMID:26155170

  18. Perspectives of the Nrf-2 signaling pathway in cancer progression and therapy

    Directory of Open Access Journals (Sweden)

    Priyanka Basak

    Full Text Available The Nuclear factor erythroid2-related factor2 (Nrf2, a master regulator of redox homoeostasis, is a key transcription factor regulating a wide array of genes for antioxidant and detoxification enzymes. It protects organs from various kinds of toxic insults. On the other hand, activation of Nrf2 is also correlated with cancer progression and chemoresistance. Downregulation of Nrf2 activity has attracted an increasing amount of attention as it may provide an alternative cancer therapy. In this review, we examine recent studies on roles of Nrf2 in several pathophysiological conditions emphasising cancer. We discuss elaborately the current knowledge on Nrf2 regulation including KEAP1-dependent and KEAP1-independent cascades. KEAP1/Nrf2 system is a master regulator of cellular response against a variety of environmental stresses. We also highlight several tightly controlled regulations of Nrf2 by numerous proteins, small molecules, toxic metals, etc. In addition, we evaluate the possible therapeutic approaches of increasing chemosensitivity via modulating Nrf2 signaling. Keywords: Nrf2, Transcription factor, KEAP1, Oxidative stress, Cell proliferation, Carcinogenesis, Chemoprevention

  19. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma

    Science.gov (United States)

    Ceccarelli, Michele; Barthel, Floris P.; Malta, Tathiane M.; Sabedot, Thais S.; Salama, Sofie R.; Murray, Bradley A.; Morozova, Olena; Newton, Yulia; Radenbaugh, Amie; Pagnotta, Stefano M.; Anjum, Samreen; Wang, Jiguang; Manyam, Ganiraju; Zoppoli, Pietro; Ling, Shiyung; Rao, Arjun A.; Grifford, Mia; Cherniack, Andrew D.; Zhang, Hailei; Poisson, Laila; Carlotti, Carlos Gilberto; Pretti da Cunha Tirapelli, Daniela; Rao, Arvind; Mikkelsen, Tom; Lau, Ching C.; Yung, W.K. Alfred; Rabadan, Raul; Huse, Jason; Brat, Daniel J.; Lehman, Norman L.; Barnholtz-Sloan, Jill S.; Zheng, Siyuan; Hess, Kenneth; Rao, Ganesh; Meyerson, Matthew; Beroukhim, Rameen; Cooper, Lee; Akbani, Rehan; Wrensch, Margaret; Haussler, David; Aldape, Kenneth D.; Laird, Peter W.; Gutmann, David H.; Noushmehr, Houtan; Iavarone, Antonio; Verhaak, Roel G.W.

    2015-01-01

    SUMMARY Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic glioma driving alterations and suboptimal disease classification. We defined the complete set of genes associated with 1,122 diffuse grade II-III-IV gliomas from The Cancer Genome Atlas and used molecular profiles to improve disease classification, identify molecular correlations, and provide insights into the progression from low- to high-grade disease. Whole genome sequencing data analysis determined that ATRX but not TERT promoter mutations are associated with increased telomere length. Recent advances in glioma classification based on IDH mutation and 1p/19q co-deletion status were recapitulated through analysis of DNA methylation profiles, which identified clinically relevant molecular subsets. A subtype of IDH-mutant glioma was associated with DNA demethylation and poor outcome; a group of IDH-wildtype diffuse glioma showed molecular similarity to pilocytic astrocytoma and relatively favorable survival. Understanding of cohesive disease groups may aid improved clinical outcomes. PMID:26824661

  20. Reaction progress pathways for glass and spent fuel under unsaturated conditions

    International Nuclear Information System (INIS)

    Bates, J.; Finn, P.; Bourcier, W.; Stout, R.

    1994-10-01

    The source term for the release of radionuclides from a nuclear waste repository is the waste form. In order to assess the performance of the repository and the engineered barrier system (EBS) compared to regulations established by the Nuclear Regulatory Commission and the Environmental Protection Agency it is necessary (1) to use available data to place bounding limits on release rates from the EBS, and (2) to develop a mechanistic predictive model of the radionuclide release and validate the model against tests done under a variety of different potential reaction conditions. The problem with (1) is that there is little experience to use when evaluating waste form reaction under unsaturated conditions such that errors in applying expert judgment to the problem may be significant. The second approach, to test and model the waste form reaction, is a more defensible means of providing input to the prediction of radionuclide release. In this approach, information related to the source term has a technical basis and provides a starting point to make reasonable assumptions for long-term behavior. Key aspects of this approach are an understanding of the reaction progress mechanism and the ability to model the tests using a geochemical code such as EQ3/6. Current knowledge of glass, UO 2 , and spent fuel reactions under different conditions are described below

  1. Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression.

    Science.gov (United States)

    Wu, Lijun; Zhang, Xu; Zhang, Bin; Shi, Hui; Yuan, Xiao; Sun, Yaoxiang; Pan, Zhaoji; Qian, Hui; Xu, Wenrong

    2016-09-01

    Exosomes are nano-sized membrane vesicles secreted by both normal and cancer cells. Emerging evidence indicates that cancer cells derived exosomes contribute to cancer progression through the modulation of tumor microenvironment. However, the effects of exosomes derived from gastric cancer cells on macrophages are not well understood. In this study, we investigated the biological role of gastric cancer cells derived exosomes in the activation of macrophages. We demonstrated that gastric cancer cells derived exosomes activated macrophages to express increased levels of proinflammatory factors, which in turn promoted tumor cell proliferation and migration. In addition, gastric cancer cells derived exosomes remarkably upregulated the phosphorylation of NF-κB in macrophages. Inhibiting the activation of NF-κB reversed the upregulation of proinflammatory factors in macrophages and blocked their promoting effects on gastric cancer cells. Moreover, we found that gastric cancer cells derived exosomes could also activate macrophages from human peripheral blood monocytes through the activation of NF-κB. In conclusion, our results suggest that gastric cancer cells derived exosomes stimulate the activation of NF-κB pathway in macrophages to promote cancer progression, which provides a potential therapeutic approach for gastric cancer by interfering with the interaction between exosomes and macrophages in tumor microenvironment.

  2. Vocational Agriculture Computer Handbook.

    Science.gov (United States)

    Kentucky State Dept. of Education, Frankfort.

    This document is a catalog of reviews of computer software suitable for use in vocational agriculture programs. The reviews were made by vocational agriculture teachers in Kentucky. The reviews cover software on the following topics: farm management, crop production, livestock production, horticulture, agricultural mechanics, general agriculture,…

  3. Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice.

    Directory of Open Access Journals (Sweden)

    Mahesh Hegde

    Full Text Available BACKGROUND: Levamisole, an imidazo(2,1-bthiazole derivative, has been reported to be a potential antitumor agent. In the present study, we have investigated the mechanism of action of one of the recently identified analogues, 4a (2-benzyl-6-(4'-fluorophenyl-5-thiocyanato-imidazo[2,1-b][1], [3], [4]thiadiazole. MATERIALS AND METHODS: ROS production and expression of various apoptotic proteins were measured following 4a treatment in leukemia cell lines. Tumor animal models were used to evaluate the effect of 4a in comparison with Levamisole on progression of breast adenocarcinoma and survival. Immunohistochemistry and western blotting studies were performed to understand the mechanism of 4a action both ex vivo and in vivo. RESULTS: We have determined the IC(50 value of 4a in many leukemic and breast cancer cell lines and found CEM cells most sensitive (IC(50 5 µM. Results showed that 4a treatment leads to the accumulation of ROS. Western blot analysis showed upregulation of pro-apoptotic proteins t-BID and BAX, upon treatment with 4a. Besides, dose-dependent activation of p53 along with FAS, FAS-L, and cleavage of CASPASE-8 suggest that it induces death receptor mediated apoptotic pathway in CEM cells. More importantly, we observed a reduction in tumor growth and significant increase in survival upon oral administration of 4a (20 mg/kg, six doses in mice. In comparison, 4a was found to be more potent than its parental analogue Levamisole based on both ex vivo and in vivo studies. Further, immunohistochemistry and western blotting studies indicate that 4a treatment led to abrogation of tumor cell proliferation and activation of apoptosis by the extrinsic pathway even in animal models. CONCLUSION: Thus, our results suggest that 4a could be used as a potent chemotherapeutic agent.

  4. DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.

    Science.gov (United States)

    Hampp, Stephanie; Kiessling, Tina; Buechle, Kerstin; Mansilla, Sabrina F; Thomale, Jürgen; Rall, Melanie; Ahn, Jinwoo; Pospiech, Helmut; Gottifredi, Vanesa; Wiesmüller, Lisa

    2016-07-26

    DNA damage tolerance facilitates the progression of replication forks that have encountered obstacles on the template strands. It involves either translesion DNA synthesis initiated by proliferating cell nuclear antigen monoubiquitination or less well-characterized fork reversal and template switch mechanisms. Herein, we characterize a novel tolerance pathway requiring the tumor suppressor p53, the translesion polymerase ι (POLι), the ubiquitin ligase Rad5-related helicase-like transcription factor (HLTF), and the SWI/SNF catalytic subunit (SNF2) translocase zinc finger ran-binding domain containing 3 (ZRANB3). This novel p53 activity is lost in the exonuclease-deficient but transcriptionally active p53(H115N) mutant. Wild-type p53, but not p53(H115N), associates with POLι in vivo. Strikingly, the concerted action of p53 and POLι decelerates nascent DNA elongation and promotes HLTF/ZRANB3-dependent recombination during unperturbed DNA replication. Particularly after cross-linker-induced replication stress, p53 and POLι also act together to promote meiotic recombination enzyme 11 (MRE11)-dependent accumulation of (phospho-)replication protein A (RPA)-coated ssDNA. These results implicate a direct role of p53 in the processing of replication forks encountering obstacles on the template strand. Our findings define an unprecedented function of p53 and POLι in the DNA damage response to endogenous or exogenous replication stress.

  5. MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer.

    Science.gov (United States)

    Wu, Zhiqiang; Wang, Ting; Fang, Meng; Huang, Wending; Sun, Zhengwang; Xiao, Jianru; Yan, Wangjun

    2018-04-06

    Breast cancer accounts for about 30% of all cancers in women, while approximately 70% breast cancer patients developed bone metastases throughout the course of their disease, highlighting the importance of exploring new therapeutic targets. Microfibrillar-associated protein 5 (MFAP5) is a component of extracellular elastic microfibril which has been confirmed to function in tissue development and cancer progression. But the role of MFAP5 in breast cancer remains unclear. The present study demonstrated that MFAP5 was up-regulated in breast cancers compared with that in normal breast tissues, and further increased in breast cancer bone metastasis. Functionally, MFAP5 overexpression accelerated breast cancer cell proliferation and migration, while an opposite effect was observed when MFAP5 was knocked down. In addition, up-regulation of MFAP5 increased the expression of MMP2 and MMP9 and activated the ERK signaling pathway. Conversely, inhibition of MFAP5 suppressed the expression of MMP2, MMP9, p-FAK, p-Erk1/2 and p-cJun. These findings may provide a better understanding about the mechanism of breast cancer and suggest that MFAP5 may be a potential prognostic biomarker and therapeutic target for breast cancer, especially for bone metastasis of breast cancer. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Receptor for activated protein kinase C 1 suppresses gastric tumor progression through nuclear factor-kB pathway.

    Science.gov (United States)

    Yong-Zheng, X; Wan-Li, M; Ji-Ming, M; Xue-Qun, R

    2015-12-01

    Nuclear factor-kB (NF-kB) activity is crucial for survival and proliferation of many kinds of malignancies, including gastric cancer (GC). The receptor for activated protein kinase C 1 (RACK1) is known to regulate tumor development, whereas the underlined mechanism has not been described clearly. We analyzed expression of RACK1 in paired human GC samples by both real-time polymerase chain reaction (PCR) and western blot. Effects of RACK inhibition with small interfering RNA or its overexpression in cultured GC cell lines were evaluated in cell viabilities. NF-kB signaling was investigated using luciferase reporter assay and real-time PCR. RACK1 was significantly decreased in GC samples. Knockdown of RACK elevated GC cell viabilities, whereas overexpression of RACK1 suppressed tumorigenesis of GC cells. Importantly, NF-kB signaling was enhanced after RACK1 expression was inhibited, suggesting the negative regulation of the pro-oncogenic NF-kB activity by RACK1 might contribute to its tumor suppressor role in GC cells. Our results support that RACK1 suppresses gastric tumor progression through the NF-kB signaling pathway.

  7. Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway.

    Science.gov (United States)

    Namatovu, Alice; Wekesa, Sabenzia Nabalayo; Tjørnehøj, Kirsten; Dhikusooka, Moses Tefula; Muwanika, Vincent B; Siegsmund, Hans Redlef; Ayebazibwe, Chrisostom

    2013-01-24

    Accurate diagnosis is pertinent to any disease control programme. If Eastern Africa is to work towards control of foot-and-mouth disease (FMD) using the Progressive Control Pathway for FMD (PCP-FMD) as a tool, then the capacity of national reference laboratories (NRLs) mandated to diagnose FMD should match this task. This study assessed the laboratory capacity of 14 NRLs of the Eastern Africa Region Laboratory Network member countries using a semi-structured questionnaire and retrospective data from the World Reference Laboratory for FMD annual reports and Genbank® through National Centre for Biotechnology Information for the period 2006-2010. The questionnaire response rate was 13/14 (93%). Twelve out of the 13 countries/regions had experienced at least one outbreak in the relevant five year period. Only two countries (Ethiopia and Kenya) had laboratories at biosecurity level 3 and only three (Ethiopia, Kenya and Sudan) had identified FMD virus serotypes for all reported outbreaks. Based on their own country/region assessment, 12/13 of these countries /regions were below stage 3 of the PCP-FMD. Quarantine (77%) and vaccination (54%) were the major FMD control strategies employed. The majority (12/13) of the NRLs used serological techniques to diagnose FMD, seven used antigen ELISA and three of these (25%) also used molecular techniques which were the tests most frequently requested from collaborating laboratories by the majority (69%) of the NRLs. Only 4/13 (31%) participated in proficiency testing for FMD. Four (31%) laboratories had no quality management systems (QMS) in place and where QMS existed it was still deficient, thus, none of the laboratories had achieved accreditation for FMD diagnosis. This study indicates that FMD diagnostic capacity in Eastern Africa is still inadequate and largely depends on antigen and antibody ELISAs techniques undertaken by the NRLs. Hence, for the region to progress on the PCP-FMD, there is need to: implement regional control

  8. Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway

    Directory of Open Access Journals (Sweden)

    Namatovu Alice

    2013-01-01

    Full Text Available Abstract Background Accurate diagnosis is pertinent to any disease control programme. If Eastern Africa is to work towards control of foot-and-mouth disease (FMD using the Progressive Control Pathway for FMD (PCP-FMD as a tool, then the capacity of national reference laboratories (NRLs mandated to diagnose FMD should match this task. This study assessed the laboratory capacity of 14 NRLs of the Eastern Africa Region Laboratory Network member countries using a semi-structured questionnaire and retrospective data from the World Reference Laboratory for FMD annual reports and Genbank® through National Centre for Biotechnology Information for the period 2006–2010. Results The questionnaire response rate was 13/14 (93%. Twelve out of the 13 countries/regions had experienced at least one outbreak in the relevant five year period. Only two countries (Ethiopia and Kenya had laboratories at biosecurity level 3 and only three (Ethiopia, Kenya and Sudan had identified FMD virus serotypes for all reported outbreaks. Based on their own country/region assessment, 12/13 of these countries /regions were below stage 3 of the PCP-FMD. Quarantine (77% and vaccination (54% were the major FMD control strategies employed. The majority (12/13 of the NRLs used serological techniques to diagnose FMD, seven used antigen ELISA and three of these (25% also used molecular techniques which were the tests most frequently requested from collaborating laboratories by the majority (69% of the NRLs. Only 4/13 (31% participated in proficiency testing for FMD. Four (31% laboratories had no quality management systems (QMS in place and where QMS existed it was still deficient, thus, none of the laboratories had achieved accreditation for FMD diagnosis. Conclusions This study indicates that FMD diagnostic capacity in Eastern Africa is still inadequate and largely depends on antigen and antibody ELISAs techniques undertaken by the NRLs. Hence, for the region to progress on the PCP

  9. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Industry

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for industry from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and training (VET) and…

  10. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Qualification & Approval Bodies

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary pulls together the relevant key findings for qualification and approval bodies from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education…

  11. Returns on Vocational Education over the Life Cycle: Between Immediate Labour Market Preparation and Lifelong Employability

    Science.gov (United States)

    Lavrijsen, Jeroen; Nicaise, Ides

    2017-01-01

    An important issue in the design of secondary-level education is the balance between conveying general and occupation-specific (vocational) skills. On the one hand, vocationally oriented programmes, providing occupation-specific skills with immediate labour market relevance, have repeatedly been shown to secure safe pathways into employment. On…

  12. Birth Order and Vocational Interest

    Science.gov (United States)

    Gandy, Gerald L.

    1973-01-01

    Investigated birth order differences and the vocational interests of 150 male college students, making use of the Strong Vocational Interest Blank. Sibling sex and interaction effects were also investigated. (DP)

  13. Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways

    DEFF Research Database (Denmark)

    Edhager, Anders Valdemar; Povlsen, Jonas Agerlund; Løfgren, Bo

    2018-01-01

    in intracellular metabolic pathways in the Zucker diabetic fatty rat heart as T2DM develops using MS based proteomics. The pre-diabetic state only induced minor pathway changes, whereas onset and late T2DM caused pronounced perturbations. Two actin-associated proteins, ARPC2 and TPM3, were up-regulated at the pre...

  14. Vocational Aptitude Test

    Directory of Open Access Journals (Sweden)

    Candiasa I Made

    2018-01-01

    Full Text Available Test for measuring vocational aptitude has been formulated and validated. There are three main constructs involved in vocational aptitude test, which are individual characteristics, activities that are likely to be selected, and professions that tend to be idolized. Individual characteristics indicate the individuals talents, whereas the activity that tends to be chosen leads to student interest in the activity, and the intended profession gives clues about the capability of themselves to pursue the profession. Content validity test with Lawse technique yields content validity ratio (CVR for all items are in the range 0.82-0.94 and content validity index (CVI = 0.88. The construct validity test yields comparative fit index (CFI = 0.918 and chi square coefficient (χ2 = 5.85 with significance (p = 0.002. These findings indicate that the test is valid either by content or construct. Furthermore, the reliability test with Alpha Cronbach found the alpha coefficient (α = 0.82. Finally, it can be concluded that vocational aptitude test can be utilized for early identification of student vocational aptitude. The hope, the test can help students to choose the appropriate vocational school, in order to obtain the better learning outcomes.

  15. Mapping Nursing Pathways

    Directory of Open Access Journals (Sweden)

    Melanie Birks

    2015-09-01

    Full Text Available Articulated education pathways between the vocational education training sector and universities provide opportunities for students wishing to progress to higher qualifications. Enrolled nurses seeking to advance their career in nursing can choose to enter baccalaureate degree programs through such alternative entry routes. Awarding of credit for prior studies is dependent on accurate assessment of the existing qualification against that which is sought. This study employed a modified Delphi method to inform the development of an evidence-based, structured approach to mapping the pathway from the nationally consistent training package of the Diploma of Nursing to the diversity of baccalaureate nursing programs across Australia. The findings of this study reflect the practical nature of the role of the enrolled nurse, particularly the greater emphasis placed on direct care activities as opposed to those related to professional development and the generation and use of evidence. These findings provide a valuable summative overview of the relationship between the Diploma of Nursing and the expectations of the registered nurse role.

  16. Dynamic changes in the inner ear function and vestibular neural pathway related to the progression of labyrinthine infarction in patient with an anterior inferior cerebellar artery infarction.

    Science.gov (United States)

    Kim, Duk Rim; Lee, Hyo-Jeong; Kim, Hyung-Jong; Hong, Sung Kwang

    2011-12-01

    To describe changes in the inner ear function and the vestibular neural pathway according to the progression of a labyrinthine infarction in a patient with an anterior inferior cerebellar artery (AICA) infarction. A 58-year-old woman with hypertension who presented with isolated inner ear symptoms similar to those of endolymphatic hydrops but finally progressed to an AICA infarction. Serial neurotologic testing according to progression to an AICA infarction and antiplatelet therapy. Radiologic findings and neurotologic parameters, including pure tone audiogram thresholds, spontaneous nystagmus, summating potentials/action potentials on electrocochleography, interaural amplitude difference on the vestibular-evoked myogenic potential test, canal paresis and fixation index on the bithermal caloric test, and gain on oculomotor tests. Our patient initially presented with sudden hearing loss and was diagnosed with an acute AICA infarction on a follow up MRI. Dynamic change in neurotologic testing was observed during disease progression. The vertigo and motion intolerance improved gradually after antiplatelet therapy. Changes in the clinical profile, which were documented during a transition from isolated labyrinthine ischemia to an AICA infarction, suggest that sensitivity to an ischemic injury is variable in different components of the labyrinthine organs in addition to providing a new insight into the response of vestibular neural pathway to ischemic injury.

  17. Insulin-Like growth factor 1 related pathways and high-fat diet promotion of transgenic adenocarcinoma mouse prostate (TRAMP) cancer progression.

    Science.gov (United States)

    Xu, H; Jiang, H W; Ding, Q

    2015-04-01

    We aimed to investigate the role of IGF-1 related pathway in high-fat diet (HFD) promotion of TRAMP mouse PCa progression. TRAMP mice were randomly divided into two groups: HFD group and normal diet group. TRAMP mice of both groups were sacrificed and sampled on the 20th, 24th and 28th week respectively. Serum levels of insulin, IGF-1 and IGF-2 were tested by ELISA. Prostate tissue of TRAMP mice was used for both HE staining and immunohistochemical staining of IGF-1 related pathway proteins, including IGF-1Rα, IGF -1Rβ, IGFBPs and AKT. The mortality of TRAMP mice from HFD group was significantly higher than that of normal diet group (23.81% and 7.14%, p=.035). The tumor incidence of HFD TRAMP mice at 20(th) week was significantly higher than normal diet group (78.57% and 35.71%, p=.022). Serum IGF-1 level of HFD TRAMP mice was significantly higher than that of normal diet TRAMP mice. Serum IGF-1 level tended to increase with HFD TRAMP mice's age. HFD TRAMP mice had higher positive staining rate of IGF-1Rα, IGF-1Rβ, IGFBP3 and Akt than normal diet TRAMP mice. IGF-1 related pathway played an important role in high-fat diet promotion of TRAMP mouse PCa development and progression. Copyright © 2014 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  18. The role of EXT and growth signalling pathways in osteochondroma and its progression towards secondary peripheral chondrosarcoma

    NARCIS (Netherlands)

    Hameetman, Liesbeth

    2007-01-01

    Osteochondroma is a cartilage capped benign bone tumour, arising at the external surface of bones preformed by endochondral ossification. A small percentage of osteochondromas can progress towards its malignant counterpart, secondary peripheral chondrosarcoma. About 15% of osteochondromas occur in

  19. A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

    Directory of Open Access Journals (Sweden)

    Bert A. ’t Hart

    2017-07-01

    Full Text Available The absence of pathological hallmarks of progressive multiple sclerosis (MS in commonly used rodent models of experimental autoimmune encephalomyelitis (EAE hinders the development of adequate treatments for progressive disease. Work reviewed here shows that such hallmarks are present in the EAE model in marmoset monkeys (Callithrix jacchus. The minimal requirement for induction of progressive MS pathology is immunization with a synthetic peptide representing residues 34–56 from human myelin oligodendrocyte glycoprotein (MOG formulated with a mineral oil [incomplete Freund’s adjuvant (IFA]. Pathological aspects include demyelination of cortical gray matter with microglia activation, oxidative stress, and redistribution of iron. When the peptide is formulated in complete Freund’s adjuvant, which contains mycobacteria that relay strong activation signals to myeloid cells, oxidative damage pathways are strongly boosted leading to more intensive pathology. The proven absence of immune potentiating danger signals in the MOG34–56/IFA formulation implies that a narrow population of antigen-experienced T cells present in the monkey’s immune repertoire is activated. This novel pathway involves the interplay of lymphocryptovirus-infected B cells with MHC class Ib/Caja-E restricted CD8+ CD56+ cytotoxic T lymphocytes.

  20. [Notch signaling pathway participates in the differentiation of hepatic progenitor cells into bile duct epithelial cells and progression of hepatic fibrosis in cholestatic liver fibrosis rat].

    Science.gov (United States)

    Mu, Y P; Zhang, X; Xu, Y; Fan, W W; Li, X W; Chen, J M; Chen, G F; Liu, P

    2017-06-08

    Objective: To investigate differentiation direction of hepatic progenitor cells (HPCs) in cholestatic liver fibrosis (CLF), and the role of Notch signaling pathway in the differentiation of HPCs. Methods: A CLF rat model was established by bile duct ligation (BDL) followed by monitoring changes of Notch signal pathway and the cellular origin of proliferating cholangiocytes. After intraperitoneal injection of DAPT (a Notch signaling inhibitor) after bile duct ligation, the progress of liver fibrosis and the proliferation of cholangiocytes after inhibition of the Notch pathway were analyzed. Results: Data showed that bile duct proliferation gradually increased along with inflammatory cell infiltration and proliferating bile duct cells surrounded by abundant collagen in the BDL group. Immunostaining confirmed markedly increased expression of CK19, OV6, Sox9 and EpCAM. In addition, RT-PCR results showed that Notch signaling pathway was activated significantly. Once the Notch signaling pathway was inhibited by DAPT, bile duct proliferation markedly suppressed along with significantly decreased the mRNA expression of CK19, OV6, Sox9 and EpCAM, compared with BDL group [(10.2±0.7) vs . (22.3±0.8), (7.6±1.5) vs . (18.1±3.7), (1.4±0.4) vs . (4.1±1.1), (1.3±0.3) vs . (5.0±1.4), respectively, P liver fibrosis was also reduced significantly. Conclusion: Notch signaling activation is required for HPCs differentiation into cholangiocytes in CLF and inhibition of the Notch signaling pathway may offer a therapeutic option for treating CLF.

  1. Vocational Trajectories within the Australian Labour Market. Research Report

    Science.gov (United States)

    Yu, Serena; Bretherton, Tanya; Schutz, Hanna

    2012-01-01

    This is a report of the first year of a three-year project entitled "Vocations: the link between post-compulsory education and the labour market." The project's aim is to research how pathways can be improved within education, within work, and between education and work. There are three strands in the project; the first strand is…

  2. Access to Elementary Education in India: Politics, Policies and Progress. CREATE Pathways to Access. Research Monograph No. 44

    Science.gov (United States)

    Little, Angela W.

    2010-01-01

    This monograph examines progress in, and policies for, access to elementary education over the past 60 years, the role played by political factors in the process of policy formulation and implementation and the drivers and inhibitors of the implementation of reforms in elementary education in recent years in India. Drawing on interviews and…

  3. New advances of TMEM88 in cancer initiation and progression, with special emphasis on Wnt signaling pathway.

    Science.gov (United States)

    Ge, Yun-Xuan; Wang, Chang-Hui; Hu, Fu-Yong; Pan, Lin-Xin; Min, Jie; Niu, Kai-Yuan; Zhang, Lei; Li, Jun; Xu, Tao

    2018-01-01

    Transmembrane protein 88 (TMEM88), a newly discovered protein localized on the cell membrane. Recent studies showed that TMEM88 was involved in the regulation of several types of cancer. TMEM88 was expressed at significantly higher levels in breast cancer (BC) cell line than in normal breast cell line with co-localized with Dishevelled (DVL) in the cytoplasm of BC cell line. TMEM88 silencing in the ovarian cancer cell line CP70 resulted in significant upregulation of Wnt downstream genes (c-Myc, cyclin-D1) and other Wnt target genes including JUN, PTIX2, CTNNB1 (β-catenin), further supporting that TMEM88 inhibits canonical Wnt signaling pathway. Wnt signaling pathway has been known to play important roles in many diseases, especially in cancer. For instance, hepatocellular carcinoma (HCC) has become one of the most common tumors harboring mutations in the Wnt signaling pathway. As the inhibitor of Wnt signaling, TMEM88 has been considered to act as an oncogene or a tumor suppressor. Up-regulated TMEM88 or gene therapy approaches could be an effective therapeutic approach against tumor as TMEM88 inhibits Wnt signaling through direct interaction with DVL. Here, we review the current knowledge on the functional role and potential clinical application of TMEM88 in the control of various cancers. Highlights Wnt signaling displays an important role in several pathogenesis of cancer. Wnt signaling pathway is activated during cancer development. TMEM88 has an impact on cancer by inhibiting canonical Wnt signaling. We discuss the importance and new applications of TMEM88 in cancer therapy. © 2017 Wiley Periodicals, Inc.

  4. UNIVERSITY AND/OR VOCATIONAL SCHOOL – WHEN AND WHY?

    Directory of Open Access Journals (Sweden)

    Mare Leino

    2018-05-01

    Full Text Available Since 2013, the university degree is free for everyone in Estonia. Vocational education has always been for free. University degrees have been valued as more academical, and vocational education because of the practical skills gained. There is a new trend in Estonia to enter into a vocational school after the university degree; and/or after one vocational education in to another vocational school. Study eagerness is always nice, but the question here is about the reason(s – is this kind of behaviour rather the sign of lifelong learning, or of wrong choices? In this question the research problem is included also – in case of wrong choices the waste of resources can be considered (from the point of view of society. In 2016, the National Audit Office of Estonia studied the progress of adults aged 25 and over, who had started acquiring vocational education (from 2010/2011 to 2014/2015 academic years before and during their studies, and in working life after the completion of their studies. The focus was on adults, because the decreasing number of young people in the state means that adults are and will remain an important target group for vocational education. The aim of this research is to analyze the background of the fact that many adults in Estonia with vocational education (36% or higher education (20% have started acquiring vocational education alongside adults without any professional education (44%. The subjects/respondents of this research were people who decided to influence the quality of their life through education. The object of the research were shcolars’ opinions about the type of education. In this research I focus on the opinion of students about university and/or vocational education. As an illustration, I discuss one case study of a highly educated person with two master degrees, who is going to start studying in a vocational school. The research question: which background impulses influence the choice of educational

  5. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Government & Policy-Makers

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for government and policy-makers from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and…

  6. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment.

    Science.gov (United States)

    Adeleye, Yeyejide; Andersen, Melvin; Clewell, Rebecca; Davies, Michael; Dent, Matthew; Edwards, Sue; Fowler, Paul; Malcomber, Sophie; Nicol, Beate; Scott, Andrew; Scott, Sharon; Sun, Bin; Westmoreland, Carl; White, Andrew; Zhang, Qiang; Carmichael, Paul L

    2015-06-05

    chemical in a case study mode. This contribution represents a 'work-in-progress' and is meant to both highlight concepts that are well-developed and identify aspects of the overall process which require additional development. To guide our understanding of what a pathways-based risk assessment could look like in practice, we chose to work on a case study chemical (quercetin) with a defined human exposure and to bring a multidisciplinary team of chemists, biologists, modellers and risk assessors to work together towards a safety assessment. Our goal was to see if the in vitro dose response for quercetin could be sufficiently understood to construct a TT21C risk assessment without recourse to rodent carcinogenicity study data. The data presented include high throughput pathway biomarkers (p-H2AX, p-ATM, p-ATR, p-Chk2, p53, p-p53, MDM2 and Wip1) and markers of cell-cycle, apoptosis and micronuclei formation, plus gene transcription in HT1080 cells. Eighteen point dose response curves were generated using flow cytometry and imaging to determine the concentrations that resulted in significant perturbation. NOELs and BMDs were compared to the output from biokinetic modelling and the potential for in vitro to in vivo extrapolation explored. A first tier risk assessment was performed comparing the total quercetin concentration in the in vitro systems with the predicted total quercetin concentration in plasma and tissues. The shortcomings of this approach and recommendations for improvement are described. This paper therefore describes the current progress in an ongoing research effort aimed at providing a pathways-based, proof-of-concept in vitro-only safety assessment for a consumer use product. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  7. Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

    DEFF Research Database (Denmark)

    Wang, Zhipeng; Jin, Haifeng; Xu, Ruodan

    2009-01-01

    ability to block progress of colitis to colon cancer, and its molecular mechanism of action are investigated. A mouse model for colitis-induced colorectal cancer was used to test the effect of triptolide on cancer progression. Treatment of mice with triptolide decreased the incidence of colon cancer...... formation, and increased survival rate. Moreover, triptolide decreased the incidence of tumors in nude mice inoculated with cultured colon cancer cells dose-dependently. In vitro, triptolide inhibited the proliferation, migration and colony formation of colon cancer cells. Secretion of IL6 and levels of JAK....... This suggests that triptolide might be a candidate for prevention of colitis induced colon cancer because it reduces inflammation and prevents tumor formation and development....

  8. Expression microarray meta-analysis identifies genes associated with Ras/MAPK and related pathways in progression of muscle-invasive bladder transition cell carcinoma.

    Directory of Open Access Journals (Sweden)

    Jonathan A Ewald

    Full Text Available The effective detection and management of muscle-invasive bladder Transition Cell Carcinoma (TCC continues to be an urgent clinical challenge. While some differences of gene expression and function in papillary (Ta, superficial (T1 and muscle-invasive (≥T2 bladder cancers have been investigated, the understanding of mechanisms involved in the progression of bladder tumors remains incomplete. Statistical methods of pathway-enrichment, cluster analysis and text-mining can extract and help interpret functional information about gene expression patterns in large sets of genomic data. The public availability of patient-derived expression microarray data allows open access and analysis of large amounts of clinical data. Using these resources, we investigated gene expression differences associated with tumor progression and muscle-invasive TCC. Gene expression was calculated relative to Ta tumors to assess progression-associated differences, revealing a network of genes related to Ras/MAPK and PI3K signaling pathways with increased expression. Further, we identified genes within this network that are similarly expressed in superficial Ta and T1 stages but altered in muscle-invasive T2 tumors, finding 7 genes (COL3A1, COL5A1, COL11A1, FN1, ErbB3, MAPK10 and CDC25C whose expression patterns in muscle-invasive tumors are consistent in 5 to 7 independent outside microarray studies. Further, we found increased expression of the fibrillar collagen proteins COL3A1 and COL5A1 in muscle-invasive tumor samples and metastatic T24 cells. Our results suggest that increased expression of genes involved in mitogenic signaling may support the progression of muscle-invasive bladder tumors that generally lack activating mutations in these pathways, while expression changes of fibrillar collagens, fibronectin and specific signaling proteins are associated with muscle-invasive disease. These results identify potential biomarkers and targets for TCC treatments, and

  9. The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants.

    Science.gov (United States)

    Meah, Farah A; DiMeglio, Linda A; Greenbaum, Carla J; Blum, Janice S; Sosenko, Jay M; Pugliese, Alberto; Geyer, Susan; Xu, Ping; Evans-Molina, Carmella

    2016-06-01

    The incidence of type 1 diabetes is increasing at a rate of 3-5% per year. Genetics cannot fully account for this trend, suggesting an influence of environmental factors. The accelerator hypothesis proposes an effect of metabolic factors on type 1 diabetes risk. To test this in the TrialNet Pathway to Prevention (PTP) cohort, we analysed the influence of BMI, weight status and insulin resistance on progression from single to multiple islet autoantibodies (Aab) and progression from normoglycaemia to diabetes. HOMA1-IR was used to estimate insulin resistance in Aab-positive PTP participants. Cox proportional hazards models were used to evaluate the effects of BMI, BMI percentile (BMI%), weight status and HOMA1-IR on the progression of autoimmunity or the development of diabetes. Data from 1,310 single and 1,897 multiple Aab-positive PTP participants were included. We found no significant relationships between BMI, BMI%, weight status or HOMA1-IR and the progression from one to multiple Aabs. Similarly, among all Aab-positive participants, no significant relationships were found between BMI, weight status or HOMA1-IR and progression to diabetes. Diabetes risk was modestly increased with increasing BMI% among the entire cohort, in obese participants 13-20 years of age and with increasing HOMA1-IR in adult Aab-positive participants. Analysis of the accelerator hypothesis in the TrialNet PTP cohort does not suggest a broad influence of metabolic variables on diabetes risk. Efforts to identify other potentially modifiable environmental factors should continue.

  10. Quantitative proteomic analysis of paired colorectal cancer and non-tumorigenic tissues reveals signature proteins and perturbed pathways involved in CRC progression and metastasis.

    Science.gov (United States)

    Sethi, Manveen K; Thaysen-Andersen, Morten; Kim, Hoguen; Park, Cheol Keun; Baker, Mark S; Packer, Nicolle H; Paik, Young-Ki; Hancock, William S; Fanayan, Susan

    2015-08-03

    Modern proteomics has proven instrumental in our understanding of the molecular deregulations associated with the development and progression of cancer. Herein, we profile membrane-enriched proteome of tumor and adjacent normal tissues from eight CRC patients using label-free nanoLC-MS/MS-based quantitative proteomics and advanced pathway analysis. Of the 948 identified proteins, 184 proteins were differentially expressed (P1.5) between the tumor and non-tumor tissue (69 up-regulated and 115 down-regulated in tumor tissues). The CRC tumor and non-tumor tissues clustered tightly in separate groups using hierarchical cluster analysis of the differentially expressed proteins, indicating a strong CRC-association of this proteome subset. Specifically, cancer associated proteins such as FN1, TNC, DEFA1, ITGB2, MLEC, CDH17, EZR and pathways including actin cytoskeleton and RhoGDI signaling were deregulated. Stage-specific proteome signatures were identified including up-regulated ribosomal proteins and down-regulated annexin proteins in early stage CRC. Finally, EGFR(+) CRC tissues showed an EGFR-dependent down-regulation of cell adhesion molecules, relative to EGFR(-) tissues. Taken together, this study provides a detailed map of the altered proteome and associated protein pathways in CRC, which enhances our mechanistic understanding of CRC biology and opens avenues for a knowledge-driven search for candidate CRC protein markers. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. [Research progress of mechanism of hypoxia-inducible factor-1α signaling pathway in condylar cartilage growth and remodeling].

    Science.gov (United States)

    Gaoli, Xu; Lili, Wu; Zhiwu, Wu; Zhiyuan, Gu

    2016-12-01

    The condylar cartilage was adapted to hypoxic conditions in vivo. However, condylar cartilage cells exposed in normoxia in vitro affect the chondrocyte phenotype and cartilage matrix formation. This condition also resulted in great difficulty in chondrocyte research. Culturing chondrocyte should be simulated in in vivo hypoxia environment as much as possible. The hypoxia-inducible factor-1α (HIF-1α) demonstrates an important transcription factor of adaptive response to hypoxic conditions. HIF-1α also plays an active role in maintaining homeostasis and function of chondrocytes. This review summarized current knowledge of the HIF-1α structure, signaling pathway, and mechanism of HIF-1α in the condylar cartilage repair.

  12. Understanding Higher Vocational Education in China: Vocationalism vs Confucianism

    Science.gov (United States)

    Xiong, Jie

    2011-01-01

    The development of higher vocational education in China embodies a global trend of vocationalism that values skills and skilled workers, which is opposite, in some ways, to the Confucian tradition in Chinese education that values theoretical knowledge related to good governance. As the cultural trend supporting the development of higher vocational…

  13. TRIM24 promotes glioma progression and enhances chemoresistance through activation of the PI3K/Akt signaling pathway.

    Science.gov (United States)

    Zhang, L-H; Yin, A-A; Cheng, J-X; Huang, H-Y; Li, X-M; Zhang, Y-Q; Han, N; Zhang, X

    2015-01-29

    The tripartite motif protein TRIM24 (tripartite motif-containing 24) has been found to play distinct roles in tumor development and progression, according to different tumor contexts. However, it remains elusive whether TRIM24 plays a role in malignant gliomas that are the most common and deadly primary brain tumors in adults. We report here that TRIM24 expression is positively correlated with glioma malignancy and is negatively associated with prognosis of patients with newly diagnosed glioblastoma, which is the most malignant form of gliomas but displays highly heterogeneous clinical outcome. The multivariate Cox regression analysis demonstrates the independent predictive value of TRIM24 expression level for overall and progression-free survival. Knockdown of TRIM24 suppresses cell proliferation, cell cycle progression, clone formation and in vivo tumor development, whereas overexpression of TRIM24 promotes cell growth. Chromatin immunoprecipitation, real-time reverse transcription-PCR and mutation analyses demonstrate that TRIM24 binds to the PIK3CA promoter via its PHD-Bromo domain to activate the transcription of PIK3CA gene, thus enhancing phosphatidylinositide 3-kinase (PI3K)/Akt signaling. The pan-PI3K inhibitor LY294002 and small interfering RNA targeting PIK3CA both abrogate the growth-promoting effect of TRIM24. Moreover, TRIM24 regulates the expression of DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) through PI3K/Akt/nuclear factor-κB signaling transduction and enhances resistance to temozolomide, the standard chemotherapeutic agent for glioblastoma. Finally, glioblastoma patients with low TRIM24 expression benefit from chemotherapy, whereas those with high TRIM24 expression do not have such benefit. Our results suggest that TRIM24 might serve as a potential prognostic marker and therapeutic target for the management of malignant gliomas.

  14. L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway.

    Directory of Open Access Journals (Sweden)

    Hisashi Ishikawa

    Full Text Available Non-alcoholic steatohepatitis (NASH is a severe form of non-alcoholic fatty liver disease characterized by lobular inflammation, hepatocellular ballooning, and fibrosis with an inherent risk for progression to cirrhosis and hepatocellular carcinoma (HCC. Mitochondrial dysfunction appears to play a role in the progression from simple steatosis to NASH. L-carnitine (L-b-hydroxy-g-N-trimethylaminobutyric acid, an essential nutrient that converts fat into energy in mitochondria, has been shown to ameliorate liver damage. The aim of the present study was to explore the preventive and therapeutic effect of L-carnitine in NASH model mice. Eight-week-old male STAM mice, a NASH-cirrhosis-hepatocarcinogenic model, were divided into 3 experimental groups and fed as follows: 1 high-fat diet (HFD (control group; 2 HFD mixed with 0.28% L-carnitine (L-carnitine group; and 3 HFD mixed with 0.01% α-tocopherol (α-tocopherol group. After 4 or 8 weeks, mice were sacrificed. Blood samples and livers were collected, and hepatic tumors were counted and measured. Livers were subjected to histological study, immunohistochemical staining of 4-hydroxynonenal and ferritin, determination of 8-OHdG levels, mRNA and protein expressions for multiple genes, and metabolomic analysis. The intestinal microbiome was also analyzed. L-carnitine increased hepatic expression of genes related to long-chain fatty acid transport, mitochondrial β-oxidation, and antioxidant enzymes following suppression of hepatic oxidative stress markers and inflammatory cytokines in NASH, and mice treated with L-carnitine developed fewer liver tumors. Although α-tocopherol resulted in NASH improvement in the same manner as L-carnitine, it increased periodontitis-related microbiotic changes and hepatic iron transport-related gene expression and led to less effective for anti-hepatocarcinogenesis. Conclusion: L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model by

  15. Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway.

    Science.gov (United States)

    Gao, Yali; Lu, Xiaohe

    2016-02-01

    The aberrant expression of MEG3 has been found in some types of cancers; however, little is known concerning the function of MEG3 in retinoblastoma. To elucidate the roles of MEG3 in retinoblastoma, MEG3 expression was quantified in 63 retinoblastoma samples and corresponding nontumor tissues in this work. Moreover, retinoblastoma cell lines were transfected with pcDNA3.1-MEG3 or si-MEG3, after which proliferation, apoptosis, and expression of β-catenin were assayed. TOP-Flash reporter assay was also used to investigate the activity of the Wnt/β-catenin pathway. The results showed that MEG3 was downregulated in retinoblastoma tissues, and the level of MEG3 was negatively associated with IIRC stages and nodal or distant metastasis. More importantly, Kaplan-Meier survival analysis demonstrated that patients with low MEG3 expression had poorer survival and multivariate Cox regression analysis revealed that MEG3 was an independent prognostic factor in retinoblastoma patients. We also observed that MEG3 expression can be modulated by DNA methylation by using 5-aza-CdR treatment. In addition, overexpression of MEG3 suppressed proliferation, promoted apoptosis, and influences the activity of the Wnt/β-catenin pathway in retinoblastoma cell lines. Furthermore, we found that Wnt/β-catenin pathway activator rescued the anticancer effect of MEG3 in retinoblastoma. In conclusion, our study for the first time demonstrated that MEG3 was a tumor suppressor by negatively regulating the activity of the Wnt/β-catenin pathway in the progression of retinoblastoma and might serve as a prognostic biomarker and molecular therapeutic target.

  16. Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression.

    Science.gov (United States)

    Nordin, Noraziah; Majid, Nazia Abdul; Hashim, Najihah Mohd; Rahman, Mashitoh Abd; Hassan, Zalila; Ali, Hapipah Mohd

    2015-01-01

    Enicosanthellum pulchrum is a tropical plant from Malaysia and belongs to the Annonaceae family. This plant is rich in isoquinoline alkaloids. In the present study, liriodenine, an isoquinoline alkaloid, was examined as a potential anticancer agent, particularly in ovarian cancer. Liriodenine was isolated by preparative high-performance liquid chromatography. Cell viability was performed to determine the cytotoxicity, whilst the detection of morphological changes was carried out by acridine orange/propidium iodide assay. Initial and late apoptosis was examined by Annexin V-fluorescein isothiocyanate and DNA laddering assays, respectively. The involvement of pathways was detected via caspase-3, caspase-8, and caspase-9 analyses. Confirmation of pathways was further performed in mitochondria using a cytotoxicity 3 assay. Apoptosis was confirmed at the protein level, including Bax, Bcl-2, and survivin, while interruption of the cell cycle was used for final validation of apoptosis. The result showed that liriodenine inhibits proliferation of CAOV-3 cells at 37.3 μM after 24 hours of exposure. Changes in cell morphology were detected by the presence of cell membrane blebbing, chromatin condensation, and formation of apoptotic bodies. Early apoptosis was observed by Annexin V-fluorescein isothiocyanate bound to the cell membrane as early as 24 hours. Liriodenine activated the intrinsic pathway by induction of caspase-3 and caspase-9. Involvement of the intrinsic pathway in the mitochondria could be seen, with a significant increase in mitochondrial permeability and cytochrome c release, whereas the mitochondrial membrane potential was decreased. DNA fragmentation occurred at 72 hours upon exposure to liriodenine. The presence of DNA fragmentation indicates the CAOV-3 cells undergo late apoptosis or final stage of apoptosis. Confirmation of apoptosis at the protein level showed overexpression of Bax and suppression of Bcl-2 and survivin. Liriodenine inhibits progression

  17. Legal Scholarship as a Vocation.

    Science.gov (United States)

    Luban, David

    2001-01-01

    Explores the more purely theoretical side of the legal scholar's vocation, using Max Weber's text on the scholar's role titled "Science as a Vocation." Discusses the consequences of the tension between law schools' generalist "pretensions" and increasingly specialist character, and Weber's fact/value distinction. (EV)

  18. Teaching Reading in Vocational Education.

    Science.gov (United States)

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This handbook on teaching reading in vocational education is designed to provide vocational education teachers with a resource to use in helping students to develop sound reading skills. Provided in the handbook are information sheets, self-checks, practice activities, and suggestions for further reading dealing with the following topics:…

  19. Challenges to Vocational Teacher Education.

    Science.gov (United States)

    Erickson, Richard C.

    1985-01-01

    Challenges to vocational teacher education include technological change that is sending large numbers of adults back to school; increasing numbers of women, minorities, and handicapped individuals who are seeking employment in nontraditional occupations; vocational preparation for jobs in the information economy; teacher recruitment; and creative…

  20. Sex Bias in Vocational Education.

    Science.gov (United States)

    Kalinowski, Edward

    Practical information is provided on sexual harassment within the vocational education context. A definition of sexual harassment is followed by examples of practices or behaviors that may be used to determine sexual harassment, including both physical conduct and communication. Possible impacts of sexual harassment in a vocational training…

  1. Vocational rehabilitation: a multidisciplinary intervention.

    Science.gov (United States)

    Gobelet, C; Luthi, F; Al-Khodairy, A T; Chamberlain, M A

    2007-09-15

    Vocational rehabilitation is by definition a multidisciplinary intervention in a process linked to the facilitation of return to work or to the prevention of loss of the work. Clinical staff in contact with a person who has lost his job (general practitioner, specialized physician) must promote vocational rehabilitation. Medical rehabilitation for those with disabilities, whether new or old, has to be followed without delay by vocational rehabilitation. It is even better if these two intertwined processes are overlapping. They involve many professionals including physiotherapists, occupational therapists, psychologists, vocational trainers, job counsellors, teachers, case-managers, job placement agencies. Vocational rehabilitation has a financial cost, borne by many state organizations (security, social system, social affairs) as well as by employers and private insurances, which are in case of accident, concerned by this process. However, the evidence suggests that this is recouped 2- to 10-fold as suggested by the British Society of Rehabilitation Medicine.

  2. The Inspiration Given by the Successful Practice of Development of Higher Vocational Education in the Developed Countries

    Science.gov (United States)

    Wu, Gaoling

    2010-01-01

    Higher vocational education is the product of economic development, scientific and technological progress. If the country does not have a well-developed vocational education, it is impossible to make a good advanced science and technology into productive forces, it is also impossible to achieve economy development in a high speed. In turn, powers…

  3. Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway

    DEFF Research Database (Denmark)

    Namatovu, Alice; Wekesa, Sabenzia Nabalayo; Tjørnehøj, Kirsten

    2013-01-01

    to diagnose FMD should match this task. This study assessed the laboratory capacity of 14 NRLs of the Eastern Africa Region Laboratory Network member countries using a semi-structured questionnaire and retrospective data from the World Reference Laboratory for FMD annual reports and Genbank (R) through...... National Centre for Biotechnology Information for the period 2006-2010. Results: The questionnaire response rate was 13/14 (93%). Twelve out of the 13 countries/regions had experienced at least one outbreak in the relevant five year period. Only two countries (Ethiopia and Kenya) had laboratories...... in Eastern Africa is still inadequate and largely depends on antigen and antibody ELISAs techniques undertaken by the NRLs. Hence, for the region to progress on the PCP-FMD, there is need to: implement regional control measures, improve the serological diagnostic test performance and laboratory capacity...

  4. Ensuring Quality Assurance in Vocational Education

    Science.gov (United States)

    Idialu, Ethel E.

    2013-01-01

    Vocational education emphasises skill acquisition. Quality assurance in vocational education is a concept that is concerned with high performance involving activities with vocational education such as teaching, learning, infrastructures, students' behaviour and the entire academic process. Quality vocational education refers to input and output of…

  5. Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice.

    Directory of Open Access Journals (Sweden)

    Ranganatha R Somasagara

    Full Text Available The consumption of berry fruits, including strawberries, has been suggested to have beneficial effects against oxidative stress mediated diseases. Berries contain multiple phenolic compounds and secondary metabolites that contribute to their biological properties.Current study investigates the anticancer activity of the methanolic extract of strawberry (MESB fruits in leukaemia (CEM and breast cancer (T47D cell lines ex vivo, and its cancer therapeutic and chemopreventive potential in mice models. Results of MTT, trypan blue and LDH assays suggested that MESB can induce cytotoxicity in cancer cells, irrespective of origin, in a concentration- and time-dependent manner. Treatment of mice bearing breast adenocarcinoma with MESB blocked the proliferation of tumor cells in a time-dependent manner and resulted in extended life span. Histological and immunohistochemical studies suggest that MESB treatment affected tumor cell proliferation by activating apoptosis and did not result in any side effects. Finally, we show that MESB can induce intrinsic pathway of apoptosis by activating p73 in breast cancer cells, when tumor suppressor gene p53 is mutated.The present study reveals that strawberry fruits possess both cancer preventive and therapeutic values and we discuss the mechanism by which it is achieved.

  6. Current Situation in Vocational Schools: Issues and Some Suggested Solutions

    Directory of Open Access Journals (Sweden)

    Reha Metin ALKAN

    2014-12-01

    Full Text Available Vocational Schools which have undertaken various missions throughout history were established in order to train intermediate staff s with suff icient knowledge and skills in their fields, in accordance with the requirements of trade, industry and services sectors and they are the most important components of ‘vocational and technical education system' today. Analyzing the education given in the vocational schools in accordance with the national and international requirements, developing technologies and the needs of business world and making the necessary arrangements in line with these will contribute to the employability and preferability of graduates of these schools in an eff icient way. Many industrialists/businessmen in our country stated that they experienced serious problems in the supply of qualified staff with suff icient knowledge and skills needed in sectors. Although much progress has been achieved in this subject, it is a fact that there are still a lot of work to be done. In this study, current situation and main troubles in vocational schools are discussed in the light of the experiences gained at Hitit University Vocational School which was established about 40 years ago in Çorum and which is one of the first high schools in Turkey and some solutions are suggested in accordance with the problems mentioned.

  7. Distance Education of Vocational High Schools in Turkey

    Directory of Open Access Journals (Sweden)

    Tuğçe GÜNTER

    2012-01-01

    Full Text Available The aim of vocational high schools is to teach qualified, high self-sufficient, self-confident, technical staff who have critical and mathematical thinking competence and who can utilize science and technology efficiently. However, because of the limitations of traditional education, students can not take enough education attendance. In this context; along with the advances in science and technology area, “Web- Based Distance Education Programme”, which provides equal education conditions to students, is developed. This programme has got great progresses in abroad, and has also started to practice in Turkish Vocational High Schools. It is determined that some Vocational High Schools have applied Web-Based Distance Education in Medical Documentation and Secretarial (MDS and Medical Laboratory Techniques (MLT Associate Degree Programmes which are also existed in Bülent Ecevit University (BEU Ahmet Erdoğan Health Services Vocational High School. It is observed that the universities, that implemented distance education in these associate degree programmes, have higher technical infrastructure and they design a constructivism-based modules. It is considered that this distance education programme for MDS and MLT Associate Degree Programmes in certain Vocational Schools, can also be implemented for students in Medical Documentation and Secretarial (MDS and Medical Laboratory Techniques (MLT which continues education by computers and overhead projector that is slightly different from traditional education.

  8. Canolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic mice.

    Directory of Open Access Journals (Sweden)

    Donghui Cao

    Full Text Available 4-Vinyl-2, 6-dimethoxyphenol (canolol is an antioxidant phenolic compound extracted from crude canola oil. In current research, K19-C2mE transgenic mice, developing hyperplastic tumors spontaneously in the glandular stomach, were used to study the mechanisms involved in the anti-inflammation and anti-tumor effects of canolol. Tg mice receiving canolol diet had a reduced tumor incidence, to 41.2%, compared with Non-treatment Tg mice, 77.8% of which had gastric tumor (P=0.002. Besides that, the mean tumor diameter was decreased from 6.5 mm to 4.5 mm (P<0.001 after canolol administration. COX-2/PGE2 pathway is known to play pivotal role in inflammation-induced gastric tumorigenesis. The neutrophils and lymphocytes infiltration was suppressed significantly, and the mRNA levels of the proinflammatory cytokines COX-2, IL-1β and IL-12b were also downregulated in gastric mucosa. Additionally, immunohistochemical analysis showed that COX-2, EP2, Gαs and β-catenin, key factors involving in PGE2 signal transduction, were positive staining with higher H scores in Non-treatment Tg mice, while the expressions were suppressed significantly by 0.1% canolol (P<0.001. In addition, tumor-suppressor miR-7 was reactivated after canolol administration, and COX-2 was showed to be a functional target of miR-7 to suppress the tumor progression. In conclusion, canolol could inhibit the gastritis-related tumor initiation and progression, and the suppression effect was correlated with the blocking up of canonical COX-2/PGE2 signaling pathway and might be regulated by miR-7.

  9. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

    International Nuclear Information System (INIS)

    Adeleye, Yeyejide; Andersen, Melvin; Clewell, Rebecca; Davies, Michael; Dent, Matthew; Edwards, Sue; Fowler, Paul; Malcomber, Sophie; Nicol, Beate; Scott, Andrew; Scott, Sharon; Sun, Bin; Westmoreland, Carl; White, Andrew; Zhang, Qiang; Carmichael, Paul L.

    2015-01-01

    specific chemical in a case study mode. This contribution represents a ‘work-in-progress’ and is meant to both highlight concepts that are well-developed and identify aspects of the overall process which require additional development. To guide our understanding of what a pathways-based risk assessment could look like in practice, we chose to work on a case study chemical (quercetin) with a defined human exposure and to bring a multidisciplinary team of chemists, biologists, modellers and risk assessors to work together towards a safety assessment. Our goal was to see if the in vitro dose response for quercetin could be sufficiently understood to construct a TT21C risk assessment without recourse to rodent carcinogenicity study data. The data presented include high throughput pathway biomarkers (p-H2AX, p-ATM, p-ATR, p-Chk2, p53, p-p53, MDM2 and Wip1) and markers of cell-cycle, apoptosis and micronuclei formation, plus gene transcription in HT1080 cells. Eighteen point dose response curves were generated using flow cytometry and imaging to determine the concentrations that resulted in significant perturbation. NOELs and BMDs were compared to the output from biokinetic modelling and the potential for in vitro to in vivo extrapolation explored. A first tier risk assessment was performed comparing the total quercetin concentration in the in vitro systems with the predicted total quercetin concentration in plasma and tissues. The shortcomings of this approach and recommendations for improvement are described. This paper therefore describes the current progress in an ongoing research effort aimed at providing a pathways-based, proof-of-concept in vitro-only safety assessment for a consumer use product

  10. Exenatide Delays the Progression of Nonalcoholic Fatty Liver Disease in C57BL/6 Mice, Which May Involve Inhibition of the NLRP3 Inflammasome through the Mitophagy Pathway

    Directory of Open Access Journals (Sweden)

    Ning Shao

    2018-01-01

    Full Text Available Objective. This study is aimed at investigating whether exenatide (Exe delays the progression of nonalcoholic fatty liver disease (NAFLD in C57BL/6 mice by targeting the NLRP3 inflammasome through the autophagy/mitophagy pathway. Methods. Thirty male C57BL/6 mice were randomly divided into three groups: control group (n=10, model group (n=10, and Exe (exenatide group (n=10. Mouse models of NAFLD and diabetes were established using a high-fat diet and streptozocin. Results. The levels of fasting blood glucose (FBG, total cholesterol (TC, and triglyceride (TG in the serum were significantly reduced after Exe treatment. The body weight, liver weight/body weight, and number of lipid droplets in the liver significantly decreased in Exe-treated mice. Treatment with Exe markedly reduced the levels of liver lipids, malondialdehyde (MDA, and alanine aminotransferase (ALT in serum and livers. The number of autophagosomes increased significantly in the Exe group. The expression of LC3A/B-II/I, Beclin-1, Parkin, and BNIP3L increased significantly, whereas NLRP3 and IL-1β proteins were suppressed after Exe treatment. Conclusion. We successfully established a mouse model of NAFLD and diabetes. Exe may reduce oxidative stress injury and inhibit the NLRP3 inflammasome by enhancing the autophagy/mitophagy pathway in liver, which has a protective effect on the liver in NAFLD and diabetes in C57BL/6 mice.

  11. MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways

    Directory of Open Access Journals (Sweden)

    Lingyu Zhao

    2017-02-01

    Full Text Available Methyl-CpG binding protein 2 (MeCP2 has recently been characterized as an oncogene frequently amplified in several types of cancer. However, its precise role in gastric cancer (GC and the molecular mechanism of MeCP2 regulation are still largely unknown. Here we report that MeCP2 is highly expressed in primary GC tissues and the expression level is correlated with the clinicopathologic features of GC. In our experiments, knockdown of MeCP2 inhibited tumor growth. Molecular mechanism of MeCP2 regulation was investigated using an integrated approach with combination of microarray analysis and chromatin immunoprecipitation sequencing (ChIP-Seq. The results suggest that MeCP2 binds to the methylated CpG islands of FOXF1 and MYOD1 promoters and inhibits their expression at the transcription level. Furthermore, we show that MeCP2 promotes GC cell proliferation via FOXF1-mediated Wnt5a/β-Catenin signaling pathway and suppresses apoptosis through MYOD1-mediated Caspase-3 signaling pathway. Due to its high expression level in GC and its critical function in driving GC progression, MeCP2 represents a promising therapeutic target for GC treatment.

  12. Age-Related Alterations in Signaling Pathways in Articular Chondrocytes: Implications for the Pathogenesis and Progression of Osteoarthritis - A Mini-Review.

    Science.gov (United States)

    van der Kraan, Peter; Matta, Csaba; Mobasheri, Ali

    2017-01-01

    Musculoskeletal conditions are a major burden on individuals, healthcare systems, and social care systems throughout the world, with indirect costs having a predominant economic impact. Aging is a major contributing factor to the development and progression of arthritic and musculoskeletal diseases. Indeed, aging and inflammation (often referred to as 'inflammaging') are critical risk factors for the development of osteoarthritis (OA), which is one of the most common forms of joint disease. The term 'chondrosenescence' has recently been introduced to define the age-dependent deterioration of chondrocyte function and how it undermines cartilage function in OA. An important component of chondrosenescence is the age-related deregulation of subcellular signaling pathways in chondrocytes. This mini-review discusses the role of age-related alterations in chondrocyte signaling pathways. We focus our attention on two major areas: age-dependent alterations in transforming growth factor-β signaling and changes in protein kinase and phosphoprotein phosphatase activities in aging chondrocytes. A better understanding of the basic signaling mechanisms underlying aging in chondrocytes is likely to facilitate the development of new therapeutic and preventive strategies for OA and a range of other age-related osteoarticular disorders. © 2016 The Author(s) Published by S. Karger AG, Basel.

  13. [Regulation of alternative CO{sub 2} fixation pathways in procaryotic and eucaryotic photosynthetic organisms]. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    The major goal of this project is to determine how microorganisms regulate the assimilation of CO{sup 2} via pathways alternative to the usual Calvin reductive pentose phosphate scheme. In particular, we are interest in the molecular basis for switches in CO{sub 2} metabolic paths. Several earlier studies had indicated that purple nonsulfur photosynthetic bacteria assimilate significant amounts of CO{sub 2} via alternative non-Calvin routes. We have deleted the gene that encodes. RubisCo (ribulose bisphosphate carboxylase/oxygenase) in both the Rhodobacter sphaeroids and Rhodospirillum rubrum. The R. sphaeroides RubisCO deletion strain (strain 16) could not grow under photoheterotrophic conditions with malate as electron donor and CO{sub 2} as the electron acceptor; however the R. rub RubisCO deletion strain (strain I-19) could. Over the past year we have sought to physiologically characterize strain 16PHC. We found that, 16PHC exhibited rates of whole-cell CO{sub 2} fixation which were significantly higher than strain 16. Strain 16PHC could not grow photolithoautotrophically in a CO{sub 2} atmosphere; however, CO{sub 2} fixation catalyzed by photoheterotrophically grown 16PHC was repressed by the addition of DMSO. Likewise, we found that cells initially grown in the presence of DMSO could induce the CO{sub 2} fixation system when DMSO was removed. Thus, these results suggested that both PHC and I-19 could be used to study alternative CO{sub 2} fixation reactions and their significance in R. sphaexoides and R. rubrum.

  14. Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF-MDM2-p53 pathway.

    Science.gov (United States)

    Zhao, Yi; Yao, Yun-hong; Li, Li; An, Wei-fang; Chen, Hong-zen; Sun, Li-ping; Kang, Hai-xian; Wang, Sen; Hu, Xin-rong

    2014-12-01

    Pokemon has been showed to directly suppress p14(ARF) expression and also to overexpress in multiple cancers. However, p14(ARF)-MDM2-p53 pathway is usually aberrant in colorectal cancer (CRC). The aim is to confirm whether Pokemon plays a role in CRC and explore whether Pokemon works through p14(ARF)-MDM2-p53 pathway in CRC. Immunohistochemistry for Pokemon, p14(ARF) and Mtp53 protein was applied to 45 colorectal epitheliums (CREs), 42 colorectal adenomas (CRAs) and 66 CRCs. Pokemon was knocked down with RNAi technique in CRC cell line Lovo to detect mRNA expression of p14(ARF) with qRT-PCR, cell proliferation with CCK8 assay, and cell cycle and apoptosis with flowcytometry analysis. The protein expression rates were significantly higher in CRC (75.8%) than in CRE (22.2 %) or CRA (38.1%) for Pokemon and higher in CRC (53.0%) than in CRE (0) or CRA (4.8%) for Mtp53, but not significantly different in CRC (86.4 %) versus CRE (93.3%) or CRA (90.5 %) for p14(ARF). Higher expression rate of Pokemon was associated with lymph node metastasis and higher Duke's stage. After knockdown of Pokemon in Lovo cells, the mRNA level of p14(ARF) was not significantly changed, the cell proliferation ability was decreased by 20.6%, cell cycle was arrested by 55.7% in G0/G1 phase, and apoptosis rate was increased by 19.0%. Pokemon enhanced the oncogenesis of CRC by promoting proliferation, cell cycle progression and anti-apoptosis activity of CRC cells independently of p14(ARF)-MDM2-p53 pathway. This finding provided a novel idea for understanding and further studying the molecular mechanism of Pokemon on carcinogenesis of CRC.

  15. Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression

    Directory of Open Access Journals (Sweden)

    Muhammad Tariq Saeed

    2016-09-01

    Full Text Available The alteration of glucose metabolism, through increased uptake of glucose and glutamine addiction, is essential to cancer cell growth and invasion. Increased flux of glucose through the Hexosamine Biosynthetic Pathway (HBP drives increased cellular O-GlcNAcylation (hyper-O-GlcNAcylation and contributes to cancer progression by regulating key oncogenes. However, the association between hyper-O-GlcNAcylation and activation of these oncogenes remains poorly characterized. Here, we implement a qualitative modeling framework to analyze the role of the Biological Regulatory Network in HBP activation and its potential effects on key oncogenes. Experimental observations are encoded in a temporal language format and model checking is applied to infer the model parameters and qualitative model construction. Using this model, we discover step-wise genetic alterations that promote cancer development and invasion due to an increase in glycolytic flux, and reveal critical trajectories involved in cancer progression. We compute delay constraints to reveal important associations between the production and degradation rates of proteins. O-linked N-acetylglucosamine transferase (OGT, an enzyme used for addition of O-GlcNAc during O-GlcNAcylation, is identified as a key regulator to promote oncogenesis in a feedback mechanism through the stabilization of c-Myc. Silencing of the OGT and c-Myc loop decreases glycolytic flux and leads to programmed cell death. Results of network analyses also identify a significant cycle that highlights the role of p53-Mdm2 circuit oscillations in cancer recovery and homeostasis. Together, our findings suggest that the OGT and c-Myc feedback loop is critical in tumor progression, and targeting these mediators may provide a mechanism-based therapeutic approach to regulate hyper-O-GlcNAcylation in human cancer.

  16. Vocational Education and Zakat: The Case Study of Punjab Vocational Training Council

    Directory of Open Access Journals (Sweden)

    Iqbal M. KHAN

    2014-08-01

    Full Text Available The aim of this research is to explore the prospect of teaching Entrepreneurship Education to those who acquire vocational skills at Punjab Vocational Training Council (PVTC. It is also to explore whether PVTC has promoted entrepreneurship through its vocational training institutes located all over Punjab. This study also deals with the concept of utilization of ‘Zakat' for the purpose of vocational education as a mode for possible replication. The research objective has been to follow the progress of this institution. It has also been to record the successes of this model of a public-private ownership, a model of utilizing the ‘Zakat' to fund education projects, a value based organization, a learning organization and a highly innovative institution. The other objective is to explore the evidence of entrepreneurship education and its effectiveness in PVTC. Literature has been reviewed on vocational training and entrepreneurship education. It also reviews experience and evidence of such practice prevailing in other environment. Combined with this is the review and conceptualization of a model based on ‘zakat'. Research Methodology used is basically qualitative; data has been collected through semi structured intensive interviews and from focus groups of stakeholders. The strategies adopted to collect data in this study are “survey”, “case study” and “grounded theory.” The data collected from semi structured interviews were concluded by thematic analysis, analyzing technique of writing reports from data. NVivo software was utilized for triangulation to reduce the data bias and increase validity by comparing primary and secondary data. The findings of this research have been that the pedagogical skills offered by PVTC's are not effective for entrepreneurial potential development. Work is required for entrepreneurial curriculum development and training of PVTCs' instructors, students and practitioners. The research also reveals

  17. Research and Analysis of SWOT on Connection between Vocational College Education and Vocational Training

    Institute of Scientific and Technical Information of China (English)

    Yingjie Zhang[1

    2016-01-01

    The connection between vocational college education and vocational training is a new way for vocational colleges and enterprises to develop together. At present, vocational college education focusing on the education level of talent training, however, it ignores the needs of workers’ vocational training based on enterprise development planning and training of professional career development. Therefore, we should strengthen the connection between vocational training and vocational education. For the establishment of modern vocational education system, we should enhance the value of human capital of workers in order to adapt to the new economic norm with important practical signifi cance.

  18. Entrepreneurship Education in Vocational Agriculture.

    Science.gov (United States)

    Williams, Jamie C.; Powell, Ronald

    1988-01-01

    The authors address the need for instruction in entrepreneurship within the vocational agriculture curriculum. They list various competencies and skills needed by agricultural entrepreneurs and discucss available curriculum materials. (CH)

  19. Namibia - Vocational Training Grant Fund

    Data.gov (United States)

    Millennium Challenge Corporation — The impact evaluation of the Vocational Training Grant Fund (VTGF) subactivity in Namibia used a random assignment design to determine the effects of VTGF-funded...

  20. Technical vocational education in India

    OpenAIRE

    溝上, 智恵子

    1999-01-01

    In India, several efforts have been made for the development of skilled manpower during the last twenty years since the launch of formal technical vocational education at school. A huge education infrastructure has developed in India. However, 45~50 percent of the population of India is still illiterate. To solve the mismatch between education and employment, a revolution in education is really needed. Additionally, there is a need for a system of National Vocational Qualifications in India a...

  1. Androgen receptor regulated microRNA miR-182-5p promotes prostate cancer progression by targeting the ARRDC3/ITGB4 pathway

    Energy Technology Data Exchange (ETDEWEB)

    Yao, Jingjing [Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, 200433 (China); Xu, Chen [Research Center of Developmental Biology, Second Military Medical University, 800th Xiangyin Road, Shanghai, 200433 (China); Department of Orthopedics, Changzheng Hospital Affiliated to Second Military Medical University, 415th Feng Yang Road, Shanghai, 200003 (China); Fang, Ziyu; Li, Yaoming [Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, 200433 (China); Liu, Houqi; Wang, Yue [Research Center of Developmental Biology, Second Military Medical University, 800th Xiangyin Road, Shanghai, 200433 (China); Translational Medicine Center, Second Military Medical University, 800th Xiangyin Road, Shanghai, 200433 (China); Xu, Chuanliang [Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, 200433 (China); Sun, Yinghao, E-mail: sunyh@medmail.com.cn [Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, 200433 (China)

    2016-05-20

    Abstracts: MicroRNAs (miRNAs) are important endogenous gene regulators that play key roles in prostate cancer development and metastasis. However, specific miRNA expression patterns in prostate cancer tissues from Chinese patients remain largely unknown. In this study, we compared miRNA expression patterns in 65 pairs of prostate cancer and para-cancer tissues by RNA sequencing and found that miR-182-5p was the most up-regulated miRNA in prostate cancer tissues. The result was validated using realtime PCR in 18 pairs of prostate cancer and para-cancer tissues. In in vitro analysis, it was confirmed that miR-182-5p promotes prostate cancer cell proliferation, invasion and migration and inhibit apoptosis. In addition, the androgen receptor directly regulated the transcription of miR-182-5p, which could target to the 3′UTR of ARRDC3 mRNA and affect the expression of ARRDC3 and its downstream gene ITGB4. For the in vivo experiment, miR-182-5p overexpression also promoted the growth and progression of prostate cancer tumors. In this regard, we suggest that miR-182-5p may be a key androgen receptor-regulated factor that contributes to the development and metastasis of Chinese prostate cancers and may be a potential target for the early diagnosis and therapeutic studies of prostate cancer. -- Highlights: •miR-182-5p is the mostly up-regulated miRNA in Chinese prostate cancer. •miR-182-5p is regulated by androgen receptor. •miR-182-5p promotes prostate cancer progression. •miR-182-5p regulates ARRDC3/ITGB4 pathway.

  2. Androgen receptor regulated microRNA miR-182-5p promotes prostate cancer progression by targeting the ARRDC3/ITGB4 pathway

    International Nuclear Information System (INIS)

    Yao, Jingjing; Xu, Chen; Fang, Ziyu; Li, Yaoming; Liu, Houqi; Wang, Yue; Xu, Chuanliang; Sun, Yinghao

    2016-01-01

    Abstracts: MicroRNAs (miRNAs) are important endogenous gene regulators that play key roles in prostate cancer development and metastasis. However, specific miRNA expression patterns in prostate cancer tissues from Chinese patients remain largely unknown. In this study, we compared miRNA expression patterns in 65 pairs of prostate cancer and para-cancer tissues by RNA sequencing and found that miR-182-5p was the most up-regulated miRNA in prostate cancer tissues. The result was validated using realtime PCR in 18 pairs of prostate cancer and para-cancer tissues. In in vitro analysis, it was confirmed that miR-182-5p promotes prostate cancer cell proliferation, invasion and migration and inhibit apoptosis. In addition, the androgen receptor directly regulated the transcription of miR-182-5p, which could target to the 3′UTR of ARRDC3 mRNA and affect the expression of ARRDC3 and its downstream gene ITGB4. For the in vivo experiment, miR-182-5p overexpression also promoted the growth and progression of prostate cancer tumors. In this regard, we suggest that miR-182-5p may be a key androgen receptor-regulated factor that contributes to the development and metastasis of Chinese prostate cancers and may be a potential target for the early diagnosis and therapeutic studies of prostate cancer. -- Highlights: •miR-182-5p is the mostly up-regulated miRNA in Chinese prostate cancer. •miR-182-5p is regulated by androgen receptor. •miR-182-5p promotes prostate cancer progression. •miR-182-5p regulates ARRDC3/ITGB4 pathway.

  3. Expressed Vocational Choices and Later Employment Compared with Vocational Preference Inventory and Kuder Preference Record-Vocational Scores

    Science.gov (United States)

    Wiggins, J. D.; Weslander, Darrell

    1977-01-01

    Expressed vocational choices were more predictive of employment status four years after high school graduation for males than were scores on either the Vocational Preference Inventory or the Kuder Preference Record--Vocational. Predictions for males were more accurate than for females on all measures. (Author)

  4. Irritable bowel syndrome and vocational stress: individual ...

    African Journals Online (AJOL)

    Irritable bowel syndrome and vocational stress: individual psychotherapy: research. ... The goal of this study was to provide individualised psychotherapy for a sample suffering from IBS and vocational stress. ... AJOL African Journals Online.

  5. The EC discourse on vocational training

    DEFF Research Database (Denmark)

    Cort, Pia

    2009-01-01

    This article traces the EC vocational training policy historically and describes the discursive alignments which brought the policy from a ‘common vocational training policy' as laid down in Article 128, in the Treaty of Rome to the Lisbon Lifelong Learning strategy. The argument is that vocational...... EC vocational training policy (Ball, What is policy? Texts, trajectories and toolboxes. Discourse, 13(2), 1993)....

  6. Vocational teacher career planning : needs and problems

    OpenAIRE

    Sajienė, Laima

    2009-01-01

    The article analyses a contradiction between vocational teacher ability to plan his/her career and requirements for the teacher professional development set by the system of education. It aims at providing theoretical and empirical justification for vocational teacher need to develop career planning skills and identify problems. The concept and objectives of vocational teacher career planning as well as career planning skills that vocational teachers should develop are defined in the article.

  7. Strategies for Translating Vocative Texts

    Directory of Open Access Journals (Sweden)

    Olga COJOCARU

    2014-12-01

    Full Text Available The paper deals with the linguistic and cultural elements of vocative texts and the techniques used in translating them by giving some examples of texts that are typically vocative (i.e. advertisements and instructions for use. Semantic and communicative strategies are popular in translation studies and each of them has its own advantages and disadvantages in translating vocative texts. The advantage of semantic translation is that it takes more account of the aesthetic value of the SL text, while communicative translation attempts to render the exact contextual meaning of the original text in such a way that both content and language are readily acceptable and comprehensible to the readership. Focus is laid on the strategies used in translating vocative texts, strategies that highlight and introduce a cultural context to the target audience, in order to achieve their overall purpose, that is to sell or persuade the reader to behave in a certain way. Thus, in order to do that, a number of advertisements from the field of cosmetics industry and electronic gadgets were selected for analysis. The aim is to gather insights into vocative text translation and to create new perspectives on this field of research, now considered a process of innovation and diversion, especially in areas as important as economy and marketing.

  8. VOCATIONAL TRAINING FOR ADULTS IN THE NETHERLANDS.

    Science.gov (United States)

    Ministry of Social Affairs and Public Health, Amsterdam (Netherlands).

    THE NETHERLANDS GOVERNMENT HAS TAKEN OVER ADULT VOCATIONAL TRAINING TO MAKE UP FOR THE ARREARS IN VOCATIONAL TRAINING CAUSED DURING WORLD WAR II AND TO ACHIEVE A SWITCHOVER OF WORKERS FROM TRADES WITH A LABOR SURPLUS TO TRADES WITH A LABOR SHORTAGE. IT HAS ESTABLISHED A NUMBER OF VOCATIONAL TRAINING CENTERS FOR THE INITIAL TRAINING OF PERSONS FOR…

  9. Vocational Education and Equality of Opportunity.

    Science.gov (United States)

    Horowitz, Benjamin; Feinberg, Walter

    1990-01-01

    Examines the concepts of equality of opportunity and equality of educational opportunity and their relationship to vocational education. Traces the history of vocational education. Delineates the distinction between training and education as enumerated in Aristotelian philosophy. Discusses the role vocational education can play in the educative…

  10. Vocational Preferences of Daughters of Alcoholics

    Science.gov (United States)

    Gade, Eldon M.; Goodman, Ronald E.

    1975-01-01

    This study was designed to examine the vocational interests of daughters of alcoholics. Mixed support was provided for the assumption that their vocational choices are nonperson oriented. Data did support the prediction of high scores on the realistic and intellectual scales of Holland's Vocational Preference Inventory. (SJL)

  11. Work Adjustment of Vocational Education Teachers.

    Science.gov (United States)

    Muncrief, Martha Crawford

    To investigate work adjustment of vocational education teachers, a nation-wide study was conducted focusing on vocational needs, job satisfaction, and job success. The study involved 180 secondary teachers from three vocational areas, business, home economics, and industrial education. A multistage sampling process was utilized to select…

  12. Food for thought : Understanding students' vocational knowledge

    NARCIS (Netherlands)

    Heusdens, W.T.

    2018-01-01

    The focus of the thesis is an exploration into students’ vocational knowledge in the context of Dutch vocational education and training (VET). The reason students’ vocational knowledge requires exploration is because there is no consensus among scholars in the field of VET about how to theorise the

  13. Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions Vitamin D pathways unbalanced in breast lesions

    International Nuclear Information System (INIS)

    Lopes, Nair; Schmitt, Fernando; Sousa, Bárbara; Martins, Diana; Gomes, Madalena; Vieira, Daniella; Veronese, Luiz A; Milanezi, Fernanda; Paredes, Joana; Costa, José L

    2010-01-01

    Breast cancer is a heterogeneous disease associated with different patient prognosis and responses to therapy. Vitamin D has been emerging as a potential treatment for cancer, as it has been demonstrated that it modulates proliferation, apoptosis, invasion and metastasis, among others. It acts mostly through the Vitamin D receptor (VDR) and the synthesis and degradation of this hormone are regulated by the enzymes CYP27B1 and CYP24A1, respectively. We aimed to study the expression of these three proteins by immunohistochemistry in a series of breast lesions. We have used a cohort comprising normal breast, benign mammary lesions, carcinomas in situ and invasive carcinomas and assessed the expression of the VDR, CYP27B1 and CYP24A1 by immunohistochemistry. The results that we have obtained show that all proteins are expressed in the various breast tissues, although at different amounts. The VDR was frequently expressed in benign lesions (93.5%) and its levels of expression were diminished in invasive tumours (56.2%). Additionally, the VDR was strongly associated with the oestrogen receptor positivity in breast carcinomas. CYP27B1 expression is slightly lower in invasive carcinomas (44.6%) than in benign lesions (55.8%). In contrast, CYP24A1 expression was augmented in carcinomas (56.0% in in situ and 53.7% in invasive carcinomas) when compared with that in benign lesions (19.0%). From this study, we conclude that there is a deregulation of the Vitamin D signalling and metabolic pathways in breast cancer, favouring tumour progression. Thus, during mammary malignant transformation, tumour cells lose their ability to synthesize the active form of Vitamin D and respond to VDR-mediated Vitamin D effects, while increasing their ability to degrade this hormone

  14. Community Governance and Vocational Education

    Science.gov (United States)

    Martasari, R.; Haryanti, R. H.; Susiloadi, P.

    2018-02-01

    Vocational education is required to create a design of education and training that is friendly and feasible for disabled people. The state has a responsibility for it, but with all the limitations, the state can not always be present. This article aims to analyze the capacity of community governance in passing vocational education for people with disabilities in Ponorogo, Indonesia. Articles are the results of research for approximately two years by using data collection techniques through interviews, documentation and observation. Source Triangulation with analysis technique using interactive model is used for data validation. The results show that there are two large capacities owned by Organisasi Sosial Rumah Kasih Sayang as community governance in conducting vocational education for the disabled person namely community credibility and community vigilance.

  15. MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway.

    Science.gov (United States)

    Pande, Hari Om; Tesfaye, Dawit; Hoelker, Michael; Gebremedhn, Samuel; Held, Eva; Neuhoff, Christiane; Tholen, Ernst; Schellander, Karl; Wondim, Dessie Salilew

    2018-05-01

    pathway, granulosa cells were treated with activin A. Activin A treatment increased cell proliferation and downregulation of both miRNA-424/503 members and its target gene, indicated the presence of negative feedback loop between activin A and the expression of miRNA-424/503. This study suggests that the miRNA-424/503 cluster members are involved in regulating bovine granulosa cell proliferation and cell cycle progression. Further, miRNA-424/503 cluster members target the SMAD7 and ACVR2A genes which are involved in the activin signalling pathway.

  16. Vocational education in the Nordic countries

    DEFF Research Database (Denmark)

    a common heritage in education policy. This volume will help strengthen the knowledge base required for transnational policy learning, and for developing vocational education internationally for the future. As a result, the book will be of interest to researchers, academics and postgraduate students......Vocational Education in the Nordic Countries: Learning from Diversity is the second of two books that disseminates new and systematic knowledge on the strengths and weaknesses of the different models of vocational education and training (VET) in four Nordic countries. Vocational education in Europe...... involved in the study of vocational education, educational studies and educational policy, as well as policy makers....

  17. Universities' Engagement with Vocationalism: Historical Perspective

    Directory of Open Access Journals (Sweden)

    Pericles 'asher' Rospigliosi

    2016-12-01

    Full Text Available The aim of this article is to explore the historical context of vocationalism in universities. It is based on an analysis of the history of the university from a vocational perspective. It looks for evidence of vocational engagement in the activities of universities over time, taking a long view from the birth of the Western University in the Middle Ages to the 1980s with the emergence of current issues of vocationalism in university education. It adopts a chronological perspective initially and then a thematic one. The main findings are: (1 vocationalism in university education is as old as the Western University itself, (2 there is evidence from the start of the Western University of vocational engagement in terms of the provision of vocationally relevant subjects, vocationally relevant skills and the development of vocationally relevant attitudes, (3 whereas most graduate employers used to be concerned with the vocationally relevant knowledge, skills and attitudes students acquired on their degree courses, most are now more concerned with graduate capacity and disposition to learn within their employment after graduation and (4 subject-centred education is compatible with university education that supports the vocational aspirations of students.

  18. The Development of Vocational Schemas.

    Science.gov (United States)

    Neimeyer, Greg J.; Metzler, April

    1987-01-01

    Together with findings relating higher structural development to higher levels of career decision-making, self-efficacy, and career decidedness, the results of three studies were interpreted as providing qualified support for the assumption that vocational schemas undergo organizational development. (Author/ABB)

  19. Vocational Interests and Basic Values.

    Science.gov (United States)

    Sagiv, Lilach

    2002-01-01

    Study 1 (n=97) provided evidence of the correlation of Holland's model of vocational interests with Schwartz' theory of basic values. Realistic career interests did not correlate with values. Study 2 (n=545) replicated these findings, showing a better match for individuals who had reached a career decision in counseling than for the undecided.…

  20. Career conversations in vocational schools

    NARCIS (Netherlands)

    Mittendorff, K.M.; Brok, den P.J.; Beijaard, D.

    2010-01-01

    The purpose of this study was to examine career conversations between teachers and students in competence-based vocational education in the Netherlands. A total of 32 career conversations were observed and analysed with respect to four elements: content, teacher activities, student activities and

  1. Vocational perspectives and neuromuscular disorders

    NARCIS (Netherlands)

    Andries, F.; Wevers, C. W.; Wintzen, A. R.; Busch, H. F.; Höweler, C. J.; de Jager, A. E.; Padberg, G. W.; de Visser, M.; Wokke, J. H.

    1997-01-01

    The present study analyses the actual occupational situation, vocational handicaps and past labour career of a group of about 1000 Dutch patients suffering from a neuromuscular disorder (NMD). On the basis of the likelihood of a substantial employment history and sufficient numbers of patients, four

  2. Vocational perspectives and neuromuscular disorders

    NARCIS (Netherlands)

    Andries, F; Wevers, CWJ; Wintzen, AR; Busch, HFM; Howeler, CJ; deJager, AEJ; Padberg, GW; deVisser, M; Wokke, JHJ

    The present study analyses the actual occupational situation, vocational handicaps and past labour career of a group of about 1000 Dutch patients suffering from a neuromuscular disorder (NMD). On the basis of the likelihood of a substantial employment history and sufficient numbers of patients, four

  3. PARENTAL ATTITUDES TOWARDS VOCATIONAL EDUCATION ...

    African Journals Online (AJOL)

    Elizabeth

    by conducting a survey involving 200 parents in Udu Local Government Area of Delta State. The result ... the concept of linkage between education and working life; for instance, ... Parental attitudes towards vocational education: Implications for counselling. Okocha ... and methodically prepared special courses of fairly long.

  4. Birth Order and Vocational Preference.

    Science.gov (United States)

    Lynch, Robert M.; Lynch, Janet

    1980-01-01

    The relationship between vocational preferences of adolescents and their birth order was examined. Firstborns were found to be overrepresented in the conventional and enterprising areas; later borns were found to be overrepresented in the social and investigative areas. (Author/GK)

  5. Microcomputer Competencies for Vocational Teachers.

    Science.gov (United States)

    Roth, Gene L.; Tesolowski, Dennis G.

    1984-01-01

    This joint research and development project of two state departments of education used the DACUM (Developing a Curriculum) process to identify microcomputer competencies for vocational instructors. Brainstorming techniques were used to identify five categories of microcomputer applications and to determine which competencies belonged in each…

  6. The Best of Both Worlds--How Vocational Education Can Enhance University Studies in Construction Management

    Science.gov (United States)

    McLaughlin, Patricia; Mills, Anthony

    2010-01-01

    Australian post-compulsory vocational or technical education and higher education (university) has traditionally been delivered separately. Attempts to collaborate on curriculum development and delivery have mostly been at the margins of articulation and educational pathways. This study examines a pilot project in construction management education…

  7. Learning How (and How Not) to Weld: Vocational Learning in Technical Vocational Education

    Science.gov (United States)

    Asplund, Stig-Börje; Kilbrink, Nina

    2018-01-01

    This article focuses on vocational learning in technical vocational education in upper-secondary school, with a special focus on the object of learning to weld. A concrete teaching situation where the learning object to weld is the focus of the interaction between a vocational teacher and an upper-secondary student was documented by a video camera…

  8. Individual predictors of adolescents’ vocational interest stabilities

    OpenAIRE

    Hirschi, Andreas

    2010-01-01

    The study investigated the predictive utility of interest profile differentiation, coherence, elevation, congruence, and vocational identity commitment and career maturity (career planning and exploration) on the 10-month interest stability of 292 Swiss eighth-grade students: profile, rank, and level stabilities were assessed. Controlling for socio-demographic and vocational interest type variables, measures of differentiated and coherent vocational interests were significant predictors of pr...

  9. Vocational Orientation of the Deaf Pupils

    OpenAIRE

    Sobolevská, Šárka

    2017-01-01

    The main goal of the bachelor thesis is to learn about vocational orientation of deaf pupils in their last years of study at selected elementary schools for the Deaf and to compare the results to results of similar studies done with pupils without hearing impairment. Based on relevant scientific sources, the paper introduces general aspects that shape vocational orientation, also describes vocational development on D. E. Super's Career Development Theory. The thesis continues with characteriz...

  10. Re-Conceptualizing the Past: Historical Data in Vocational Interest Research

    Science.gov (United States)

    Armstrong, Patrick Ian; Rounds, James; Hubert, Lawrence

    2008-01-01

    Noteworthy progress has been made in the development of statistical models for evaluating the structure of vocational interests over the past three decades. It is proposed that historically significant interest datasets, when combined with modern structural methods of data analysis, provide an opportunity to re-examine the underlying assumptions…

  11. Reforming Vocational Education and Training

    DEFF Research Database (Denmark)

    Friche, Nanna; Kondrup, Sissel

    this must be understood as organizations, whose survival is contingent to a stabile level of legitimacy. Legitimacy is ensured by responding appropriately to the expectations that exist in the organization's environment. For vocational schools in Denmark legitimacy is fundamental and ensured by trust from......). In this paper focus is solely on the Agreement, which is due to the assumption that the Agreement as empirical piece provides evidence for and knowledge on the political view on the formal existence and legitimacy of VET....

  12. Constructing and Practicing Vocational Knowledge at Workplace ...

    African Journals Online (AJOL)

    This is followed by an account of sources of knowledge synthesized from the socio-cultural literature. This is a brief description of a study which examined how vocational knowledge is constructed by individuals participating in three different settings and the findings reported. It is concluded that vocational knowledge is ...

  13. Gasoline Engine Mechanics. Florida Vocational Program Guide.

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This vocational program guide is intended to assist in the organization, operation, and evaluation of a program in gasoline engine mechanics in school districts, area vocational centers, and community colleges. The following topics are covered: job duties of small-engine mechanics; program content (curriculum framework and student performance…

  14. Remarks [to the] American Vocational Association Convention.

    Science.gov (United States)

    Seltz, Larry

    The current trend toward expanded use of automation and computers in manufacturing has increased the need for a working partnership between industry and vocational education. One such partnership involves the members of the personnel development staff at Nissan Motors in Smyrna, Tennessee and local secondary and postsecondary vocational education…

  15. Technical and Vocational Education for Zimbabwe's Rural ...

    African Journals Online (AJOL)

    The main purpose of this paper is to highlight some issues and concerns in the Zimbabwean educational system in general, and in particular, issues and concerns within the purview for technical and vocational education. The paper will further provoke debate within the context of technical and vocational education as a ...

  16. Identity Change during Vocational Teacher Education

    DEFF Research Database (Denmark)

    Duch, Henriette

    where the teacher is employed. Regardless of the teacher’s educational background, he has to attend the same course when he is employed at a vocational school. During that education, the teacher is in transition to become a vocational teacher. It is mandatory to complete the Diploma of Education in four...

  17. Proficiency Forms and Vocational Pedagogical Principles

    Science.gov (United States)

    Inglar, Tron

    2014-01-01

    This article is based on research on experiential learning and vocational teachers. The author describes his analysis of curricula for the vocational teacher education and explains the education´s purpose, content, and methods. In 1975, education dramatically changed from an academic tradition with dissemination of many disciplines to a holistic…

  18. Casting No Shadow: Assessing Vocational Overshadowing

    Science.gov (United States)

    Magee, Ilene M.; Whiston, Susan C.

    2010-01-01

    Vocational overshadowing has been defined as an underemphasis on career concerns when personal problems coexist. This study explored whether vocational overshadowing occurred based on observers' perception of the setting (i.e., either career counseling center or mental health counseling center). Clinicians in-training viewed an analogue counseling…

  19. An Investigation of Vocational Interests and Noctcaelador

    Science.gov (United States)

    Kelly, William E.

    2005-01-01

    This study explored the relationship between vocational interests and noctcaelador, defined as strong interest in, and psychological attachment to, the night sky. University students (N = 134) completed the Vocational Preference Inventory (Form C) and the Noctcaelador Inventory. The results indicated that students scoring higher on noctcaelador…

  20. The Structure of Vocational Interests in Romania

    Science.gov (United States)

    Iliescu, Dragos; Ispas, Dan; Ilie, Alexandra; Ion, Andrei

    2013-01-01

    Using data provided by the Self-Directed Search (SDS) on a sample of 1,519 participants comprising 3 subsamples containing high school students, university students, and working adults, the authors examine the structure of vocational interests in Romania. Three competing structural models of vocational interests (Holland's circumplex model and…

  1. Alleviating Poverty Through Vocational Education: The Nigerian ...

    African Journals Online (AJOL)

    The paper concludes that well-articulated vocational education policy and programmes will assist in employment generations and poverty reduction in Nigeria. Keywords: Alleviating Poverty, Vocational Education, Nigerian Experience Journal of Technology and Education in Nigeria Vol. 10 (2) 2005: pp. 10-14 ...

  2. General or Vocational Curriculum: LD Preference

    Science.gov (United States)

    Dupoux, Errol

    2008-01-01

    This study assessed the perceptions of high school students with learning disabilities about the suitability or preference of an academic or vocational curriculum. Students were administered the Vocational Academic Choice Survey (VACS), designed to measure students' perceptions of which curriculum is more suitable for them. Results revealed that a…

  3. Interests in School Subjects and Vocational Preference.

    Science.gov (United States)

    Sjoberg, Lennart; Drottz, Britt-Marie

    1983-01-01

    Reports a study in which Swedish high school students' academic interests were related to perceived effort, ability, and perceived vocational job prospects. Notes that academic interests were based on subjects' logical appeal and practical value. Notes that vocational preferences correlated strongly with individual job prospects but weakly with…

  4. Relationships Among Categories of Vocational Preference

    Science.gov (United States)

    Underwood, K.

    1972-01-01

    The dimensions of preference were arranged in two independent groups: the first defined by occupational titles, curriculum subjects, and vocational life goals; and the second by job attributes and general life goals. The implications of this finding for the nature of vocational preference and certain counseling activities are discussed. (Author)

  5. Fashion Marketing. Florida Vocational Program Guide.

    Science.gov (United States)

    Florida State Univ., Tallahassee. Center for Instructional Development and Services.

    This vocational program guide is intended to assist in the organization, operation, and evaluation of a program in fashion marketing in school districts, area vocational centers, and community colleges. The following topics are covered: program content (job duties of wholesale and retail clothing salespersons and curriculum framework and student…

  6. Vocational Assessment. Policy Paper Series: Document 6.

    Science.gov (United States)

    Stodden, Robert A., Ed.

    This collection of four policy papers on vocational assessment for the handicapped deals with personnel development, interagency coordination, current research and development, and providing individualized assessment services. Discussed in the initial paper on program improvement in vocational assessment for the handicapped are federal legislation…

  7. USING DIDACTIC EQUIPMENT IN VOCATIONAL SUBJECTS TEACHING

    OpenAIRE

    JIROUT, Jiří

    2011-01-01

    Baccalaureate Work ?Using Didactic Equipment In Vocational Subjects Teaching? describes various methods of teaching and using didactic engineering in education. Theoretic part describes general aspects of using didactic engineering, teaching methods a and ways how to use didactic engineering in teaching vocational subjects. Practical part finds how students appreciate using modern didactic aids and engineering in education.

  8. Leadership Skills among Technical and Vocational Educators

    Science.gov (United States)

    Zakaria, Nurazyan Zahidah; Jizat, Nor Atikah Md.; Zakaria, Normah

    2015-01-01

    The purpose of leadership skills among technical and vocational educator are to prepare them towards effective organization. Effective leadership is widely accepted as being a key constituent in achieving organization improvement and to examine. This study aimed to gauge the leadership skills among technical and vocational educators effectiveness…

  9. Students' Views of Learning in Vocational Education.

    Science.gov (United States)

    Eklund-Myrskog, Gunilla

    1997-01-01

    Conceptions of learning and approaches to learning within vocational education were studied with 30 Finnish students of automotive mechanics. About half the students took a quantitative view of learning and favored a surface approach. Encouraging a qualitative view of learning and deeper approaches in vocational education is discussed. (SLD)

  10. Vocation in Theology and Psychology: Conflicting Approaches?

    Science.gov (United States)

    Rotman, Marco

    2017-01-01

    Recent contributions in the fields of psychology, sociology, and theology reveal opposing attitudes about the subject of calling or vocation with regard to one's work. Whereas psychologists have rediscovered the concept, theologians increasingly show reluctance to accept a vocational view of work. In offering an alternative perspective, this…

  11. Hispanic Vocational Exploration Project. Final Report.

    Science.gov (United States)

    Centro De La Comunidad, Inc., New London, CT.

    During its second year, the Hispanic Vocational Exploration Project recruited eighth and ninth grade Hispanic youth for a four-week cycle, after-school, career exploratory program at Southeastern Regional Vocational Technical School, Groton, Connecticut. A series of career education workshops was the other major project activity. Supportive…

  12. Returns on vocational education over the life cycle: Between immediate labour market preparation and lifelong employability

    Science.gov (United States)

    Lavrijsen, Jeroen; Nicaise, Ides

    2017-04-01

    An important issue in the design of secondary-level education is the balance between conveying general and occupation-specific (vocational) skills. On the one hand, vocationally oriented programmes, providing occupation-specific skills with immediate labour market relevance, have repeatedly been shown to secure safe pathways into employment. On the other hand, these programmes tend to put less emphasis on developing general knowledge, skills and competencies, including numeracy and literacy, which are foundational to lifelong learning. Hence, when the needs of the labour market change, employees who opted for a vocational track when they were at secondary school risk being less flexible in adapting to such changes later in their career. The authors of this article examine whether this results in a trade-off between short-term gains and long-term losses by considering differences in the labour market careers of vocationally and generally educated respondents in the 2012 Programme for the International Assessment of Adult Competencies (PIAAC). Their results suggest that early labour market benefits of vocational specialisation decrease over time; the authors relate this to its lower ability to equip secondary school students - future employees - with skills for lifelong learning.

  13. Hands-on creativity in Vocational Education

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    and therefore not well suited for VET comprising production, handcraft and industry. In Europe, vocational education schemes are considered the solid base on which almost all kinds of industry and craft depend. If Europe is to retain its innovative capacity, then vocational education, especially the capacity......This presentation poses the question: what conception of the phenomenon of creativity is best suited to the field of vocational education? VET (Vocational Education and Training) aims to prepare people for employment in craft and industry. In this field, there is an ever-growing requirement...... for creativity and innovation. In response, it is my concern that an understanding of creativity be developed with vocational education and training in mind. It is not enough to import models from other areas, where the distinction between ideas and production or creativity and execution is often relatively hazy...

  14. Vocational guidance in social volunteering

    Directory of Open Access Journals (Sweden)

    Nikolay S. Pryazhnikov

    2017-03-01

    Full Text Available The paper discusses the possibilities and limitations of vocational guidance in the social volunteering system. The essence of volunteer work is closely related with assistance to desperate people in searching for the meaning of living, often coinciding with labour activity that are deemed in terms of “the main matter of life” and “the leading activity”. For adolescents, it is the choice of career, and for adults, it is the work proper (i.e. an essential condition for personal self-realization. The problem of “forced volunteering” for experts in vocational guidance also means that they often have to work voluntarily and unselfishly outside the official guidelines. To clarify the terms «volunteer» and «a person in desperate need of help» the study used the method of analyzing the documents, e.g. the Regulations on Social Volunteering, the generalization of psychological sources, the initial survey of university students as active supporters of the volunteer movement, On the essence of volunteering and the place of career guidance in selfless social work. Vocational guidance is not excluded from the general system of volunteerism, but has an insufficiently defined status and low popularity among participants in social volunteering. Also, the problem of «forced volunteering» of experts in career counseling, which often requires voluntary and unselfish performance of quality work outside the framework of official instructions, is also indicated. Simultaneously, positive aspects of such disinterested career initiatives are noted, in particular, less control by the official inspectors (or customers and, accordingly, greater freedom of creativity than when someone else does the work.

  15. Vocational Interests of Intellectually Gifted and Highly Achieving Young Adults

    Science.gov (United States)

    Vock, Miriam; Koller, Olaf; Nagy, Gabriel

    2013-01-01

    Background: Vocational interests play a central role in the vocational decision-making process and are decisive for the later job satisfaction and vocational success. Based on Ackerman's (1996) notion of "trait complexes," specific interest profiles of gifted high-school graduates can be expected. Aims: Vocational interests of gifted and…

  16. Dewey on Educating Vocation: Bringing Adult Learning to the University

    Science.gov (United States)

    Keitges, Mark

    2016-01-01

    This paper addresses Dewey's complex notion of vocation--particularly his idea of multiple vocational activities--and relates it to educating for vocation in colleges and universities. The author argues that higher educators can best respect a student's autonomy as a chooser--with multiple potential vocations--by giving him or her multiple…

  17. 20 CFR 405.10 - Medical and Vocational Expert System.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Medical and Vocational Expert System. 405.10... Vocational Expert System. (a) General. The Medical and Vocational Expert System is comprised of the Medical... Vocational Expert System. (3) Experts who provide evidence at your request. Experts whom you ask to provide...

  18. EFFICIENCY FINANCIAL RESOURCES IN VOCATIONAL EDUCATION

    Directory of Open Access Journals (Sweden)

    Nataliia Kovernuk

    2016-11-01

    Full Text Available The purpose of writing is to research and analyze the effectiveness of financial resources in vocational education in Ukraine and develop practical recommendations for their improvement. To research and analyze the practices of formation and use of financial resources in vocational education. Research conducted by the methods of empirical knowledge, analysis, clustering, comparison, observation, synthesis, graphical analysis. The measures effective use of financial resources in vocational education in Ukraine. Methodology is actual work of scientists and researchers. Results are exploring of the practice of planning expenditures of state and local budgets for vocational education concluded that in planning expenditure dominates the normative method of budget planning. This discrepancy established approaches to the development of standards of employee’s vocational institutions and expenditures of staff, on the one hand, and the required planning spending on vocational education. When planning educational grants for training labor to local budgets is determined by the amount of expenditures that are relevant to the intergovernmental transfers, which include, in particular, spending on vocational education. Although the legislation stipulates the independence of local budgets and calculation of expenditures that are relevant to the intergovernmental transfers should be done only to determine the amount of educational grants for training labor, in practice there is a significant limitation of the autonomy of local governments in the planning of local budgets. Thus, the deterioration of the efficiency of spending on vocational education due to increasing labor costs and labor charges. The reason for this was the dynamics as increased wages and a change in the number of employees engaged in technical and vocational education. Value. The analysis of public expenditure planning practices and local budgets for vocational education concluded that in

  19. Students' Meaning-Making and Sense-Making of Vocational Knowledge in Dutch Senior Secondary Vocational Education

    Science.gov (United States)

    Bijlsma, Nienke; Schaap, Harmen; de Bruijn, Elly

    2016-01-01

    Meaning-making and sense-making are generally assumed to be part of students' personal vocational knowledge development, since they contribute to both students' socialisation in a vocation and students' personalisation of concepts, values and beliefs regarding that vocation. However, how students in vocational education acquire meaning and make…

  20. Vocational Training in the European Union

    Directory of Open Access Journals (Sweden)

    Mehmet BALCI

    2013-01-01

    Full Text Available European Union requires some standards in all areas. Today, the importance of training qualified individuals which holds an important place in the development of countries increases and certain standards are adopted creating common European Union tools in the field of vocational and technical education. In this study, vocational education and training policies system and the standards adopted by the European Union are discussed. Furthermore, this study was accepted as a European Union project in 2010 and the results obtained from the Leonardo Da Vinci Life Learning European Union project called “Web Based Basic Vocational Training” between the years 2010-2012 were presented. Since the partners of these projects are Turkey, Spain and Germany, the structure of vocational education, institutions of public and private vocational education and the diplomas and certificates entitled after these educations are included. As Turkey is on its way to become a European Union member, a number of advices are presented for Turkey to reach its destination about vocational education standards that European Union has aimed. The purpose of the study is not only to be a guide for the young who want to get professional training in the countries that are European Union members or candidates about how and where to have education opportunities but also to give a chance for trainers and training managers, participating in vocational training, so as to glimpse different practices from different countries and compare these practices between the countries of European Union and their countries. The study is also very important as it has the opportunities for training managers to see if their countries' vocational education is close enough to vocational education in European Union.

  1. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Tertiary Education Providers & School Educators

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for tertiary education providers and school educators from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between…

  2. Pathways through Secondary School in a Comprehensive System: Does Parental Education and School Attended Affect Students' Choice?

    Science.gov (United States)

    Chesters, Jenny

    2015-01-01

    As the Australian labour market restructured during the 1980s and 1990s, Year 12 retention rates more than doubled between 1983 and 1993 secondary schools diversified to include vocational education and training programs as alternative pathways through school. From a human capital perspective, the completion of vocational qualifications in school…

  3. The feasibility of vocational rehabilitation in subjects with severe mental illness Factibilidad de la rehabilitación vocacional en personas con enfermedades mentales graves

    OpenAIRE

    Stefan Watzke; Anja Galvao

    2008-01-01

    Vocational rehabilitation represents an important element within the mental health care system. To ensure the success of rehabilitation, programs of varying degrees of complexity are needed in order to meet patients’ abilities and needs. Rehabilitation success must be examined multidimensionally and not be reduced to the mere integration into competitive employment. Success is also represented by progress in the level of vocational integration, strengthening of work capabilities, the improvem...

  4. Medical sociology as a vocation.

    Science.gov (United States)

    Bosk, Charles L

    2014-12-01

    This article extends Weber's discussion of science as a vocation by applying it to medical sociology. Having used qualitative methods for nearly 40 years to interpret problems of meaning as they arise in the context of health care, I describe how ethnography, in particular, and qualitative inquiry, more generally, may be used as a tool for understanding fundamental questions close to the heart but far from the mind of medical sociology. Such questions overlap with major policy questions such as how do we achieve a higher standard for quality of care and assure the safety of patients. Using my own research, I show how this engagement takes the form of showing how simple narratives of policy change fail to address the complexities of the problems that they are designed to remedy. I also attempt to explain how I balance objectivity with a commitment to creating a more equitable framework for health care. © American Sociological Association 2014.

  5. Studies of transport pathways of Th, U, REE's, Ra-228, and Ra-226 from soil to farm animals. Progress report, April 1-December 31, 1983

    International Nuclear Information System (INIS)

    Eisenbud, M.; Franca, E.P.

    1984-01-01

    This is a report on the Transport Pathways of Thorium, Uranium, Rare Earths Elements, Radium-228 and Radium-226 from Soil to Farm Animals. The investigation is taking place in the State of Minas Gerais, Brazil, where an ore body (Morro de Ferro) exists that contains about 30,000 metric tons of thorium and more than 50,000 metric tons of rare earth elements. The ore body, which is believed to be about 60 million years old, has eroded to the surface and has been inundated by ground water. Nearby farmers are cooperating in the study. The analytical procedures have been modified to adapt them to the large volumes of biological material. The soils from the farm plots have been sampled, analyzed and characterized by standard pedological methods. Analyses for most of the substances of interest have been completed in pilot samples of vegetables and cow bone

  6. Revitalizing Technical and Vocational Education Training for ...

    African Journals Online (AJOL)

    Administrator

    integrating technical and vocational education and training ... A cost sharing agreement was therefore signed in 2000, between. UNESCO and Nigeria Federal Ministry of .... done in the area of the target population, logistic and welfare.

  7. Students’ Attitudes towards Vocational Foreign Language Course

    OpenAIRE

    Ozer, Selda; Yılmaz, Ercan

    2016-01-01

    The aim of the study was to determine students’attitudes towards Vocational Foreign Language Course and if the their attitudesdisplay significant differences in terms of gender, age, department, the placethey live, passing marks, the type of high school they graduated from, theirmothers’ and fathers’ graduation levels and being abroad. The study was carriedout in descriptive survey method. The population of the study comprised ofsenior students at two vocational colleges of Nevşehir Hacı Bekt...

  8. Benchmarking Danish Vocational Education and Training Programmes

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wittrup, Jesper

    This study paper discusses methods whereby Danish vocational education and training colleges can be benchmarked, and presents results from a number of models. It is conceptually complicated to benchmark vocational colleges, as the various colleges in Denmark offer a wide range of course programmes...... attempt to summarise the various effects that the colleges have in two relevant figures, namely retention rates of students and employment rates among students who have completed training programmes....

  9. Vocational Education in Tourism: Conceptual Framework Problems

    Directory of Open Access Journals (Sweden)

    Galina Shchuka

    2012-12-01

    Full Text Available This article analyzes the basic concepts that define the essence of the system of vocational education and helps to analyze the problem of tourism staffing support. According to authors’ hypothesis, the personnel problem is related to the imperfection of the tourism conceptual framework. As of all enterprises of travel industry only travel agencies and accommodation facilities work with tourists, the author proves that personnel training for these businesses is the major objective of vocational training in tourism.

  10. Regional gray matter correlates of vocational interests.

    Science.gov (United States)

    Schroeder, David H; Haier, Richard J; Tang, Cheuk Ying

    2012-05-16

    Previous studies have identified brain areas related to cognitive abilities and personality, respectively. In this exploratory study, we extend the application of modern neuroimaging techniques to another area of individual differences, vocational interests, and relate the results to an earlier study of cognitive abilities salient for vocations. First, we examined the psychometric relationships between vocational interests and abilities in a large sample. The primary relationships between those domains were between Investigative (scientific) interests and general intelligence and between Realistic ("blue-collar") interests and spatial ability. Then, using MRI and voxel-based morphometry, we investigated the relationships between regional gray matter volume and vocational interests. Specific clusters of gray matter were found to be correlated with Investigative and Realistic interests. Overlap analyses indicated some common brain areas between the correlates of Investigative interests and general intelligence and between the correlates of Realistic interests and spatial ability. Two of six vocational-interest scales show substantial relationships with regional gray matter volume. The overlap between the brain correlates of these scales and cognitive-ability factors suggest there are relationships between individual differences in brain structure and vocations.

  11. Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the JAK/STAT-3 signalling pathway.

    Science.gov (United States)

    Baba, Abdul Basit; Nivetha, Ramesh; Chattopadhyay, Indranil; Nagini, Siddavaram

    2017-11-01

    Blueberries, a rich source of anthocyanins have attracted considerable attention as functional foods that confer immense health benefits including anticancer properties. Herein, we assessed the potential of blueberry and its major constituent malvidin to target STAT-3, a potentially druggable oncogenic transcription factor with high therapeutic index. We demonstrate that blueberry abrogates the JAK/STAT-3 pathway and modulates downstream targets that influence cell proliferation and apoptosis in a hamster model of oral oncogenesis. Further, we provide mechanistic evidence that blueberry and malvidin function as STAT-3 inhibitors in the oral cancer cell line SCC131. Blueberry and malvidin suppressed STAT-3 phosphorylation and nuclear translocation thereby inducing cell cycle arrest and mitochondrial-mediated apoptosis. However, the combination of blueberry and malvidin with the STAT-3 inhibitor S3I-201 was more efficacious in STAT-3 inhibition relative to single agents. The present study has provided leads for the development of novel combinations of compounds that can serve as inhibitors of STAT-mediated oncogenic signalling. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Vocational Education and Training in Kuwait: Vocational Education versus Values and Viewpoints

    Science.gov (United States)

    Bilboe, Wendy

    2011-01-01

    Since the opening up of private universities and colleges in the Kuwait education system in the late 1990s, there has been an explosion of tertiary institutions (both domestic and international) established in the country, with many of them offering vocational education and training. The move towards vocational and educational training forms part…

  13. Testing Vocational Interests and Personality as Predictors of Person-Vocation and Person-Job Fit

    Science.gov (United States)

    Ehrhart, Karen Holcombe; Makransky, Guido

    2007-01-01

    The fit between individuals and their work environments has received decades of theoretical and empirical attention. This study investigated two antecedents to individuals' perceptions of fit: vocational interests and personality. More specifically, the authors hypothesized that vocational interests assessed in terms of the Career Occupational…

  14. Contextual Factors and Vocational Interests in South Asian Americans' Vocational Development

    Science.gov (United States)

    Kantamneni, Neeta; Fouad, Nadya A.

    2013-01-01

    Examining vocational interests is a central component of career counseling; yet, little research has investigated structural differences for specific subpopulations or the role of cultural factors on vocational interests. The purpose of this study was to examine the structure of interests, congruence between expressed and measured interests, and…

  15. Vocational School Students’ Vocational Identity and Their Views on the Functions of School

    Directory of Open Access Journals (Sweden)

    Cheng-Yen Shih

    2016-06-01

    Full Text Available This study aims to explore the students’ viewpoints on the functions of vocational schools, as well as the connection between their vocational identity and their opinions on the functions of schools. After understanding the students’ views of the practical support their schools have provided, the curricula and learning goals of vocational schools were reexamined. Ten in-service vocational school students, between the ages of 18-22, were invited to participate in this study. Each student was interviewed individually by the researchers for approximately 60 minutes and they were asked to use mind maps to express their viewpoints. The results showed that students regarded the vocational school as a means to obtain diplomas and professional licenses, a place to get to know friends, and a place to escape from the pressures of reality. Students with higher vocational commitment tended to care about their careers more deeply. In order to obtain a degree or professional licenses, a higher salary, and greater self-affirmation, these students actively engaged in learning. Students with lower vocational commitment tended to be in the stage of career exploration as they kept searching for career goals. They were confused by their current jobs and with the school curriculum; however, when an identified career role model or a hopeful vision was demonstrated to them, some students with lower vocational commitment would be stimulated to gain a positive career motivation and expressed the flexibility to have a career/life change.

  16. Some Data Concerning the Vocational Preference Inventory Scales and the Strong Vocational Interest Blank

    Science.gov (United States)

    Cockriel, Irvin W.

    1972-01-01

    Occupational scales of the Vocational Preference Inventory were correlated with the Basic Interest scales of the Strong Vocational Interest Blank. The 285 subjects were women freshmen in a College of Education. The results indicate that the scales are not highly correlated. (Author)

  17. The Status of Vocational Teacher Education in University Council for Vocational Education Member Institutions. Research Report.

    Science.gov (United States)

    Anderson, B. Harold

    The purpose of the study reported in this document was to describe the quantitative and qualitative characteristics of the vocational teacher education programs among institutions that are members of the University Council for Vocational Education. A questionnaire was mailed to representatives of each member institution in October 1985, with a 100…

  18. Diagnostic Vocational Assessment for Special Needs Student Candidates for Vocational Training.

    Science.gov (United States)

    Blackstone Valley Regional Vocational School District, Upton, MA.

    A project was conducted to bridge the gap between the coneptualized model of vocational evaluation within a rehabilitation framework and the needs of a changing career development model within an educational setting. The project focus was on ascertaining the state of the art of vocational assessment of special needs individuals, then building a…

  19. Relationship of Vocational Satisfaction to the Correspondence of Job Reinforcement and Vocational Needs.

    Science.gov (United States)

    Golden, Robert R.; Weiss, David J.

    The Theory of Work Adjustment proposes that vocational satisfaction is a function of the correspondence between the reinforcers in the work environment and the individual's vocational needs. This hypothesis is tested by comparing the means and variances of measures of satisfaction for groups differing in degree of need-reinforcer correspondence.…

  20. Moderate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway

    Directory of Open Access Journals (Sweden)

    Zhenli Luo

    2017-01-01

    Full Text Available In order to investigate the effects of autophagy induced by rapamycin in the development of atherosclerosis plaque we established murine atherosclerosis model which was induced in ApoE−/− mice by high fat and cholesterol diet (HFD for 16 weeks. Rapamycin and 3-Methyladenine (MA were used as autophagy inducer and inhibitor respectively. The plaque areas in aortic artery were detected with HE and Oil Red O staining. Immunohistochemical staining were applied to investigate content of plaque respectively. In contrast to control and 3-MA groups, rapamycin could inhibit atherosclerosis progression. Rapamycin was able to increase collagen content and a-SMA distribution relatively, as well as decrease necrotic core area. Then we used MOVAS and culture with ox-LDL for 72 h to induce smooth muscle-derived foam cell model in vitro. Rapamycin and 3-MA were cultured together respectively. Flow cytometry assay and SA-β-Gal staining experiments were performed to detect survival and senescence of VSMCs. Western blot analysis were utilized to analyze the levels of protein expression. We found that rapamycin could promote ox-LDL-induced VSMCs autophagy survival and alleviate cellular senescence, in comparison to control and 3-MA groups. Western blot analysis showed that rapamycin could upregulate ULK1, ATG13 and downregulate mTORC1 and p53 protein expression.

  1. The European Dimensions of Vocational Training

    Directory of Open Access Journals (Sweden)

    Sós Tamás

    2015-12-01

    Full Text Available The research examined the connection between vocational education, training and the world of work, and the social situation in Hungary in a European outlook. The accentual issues of the analysis disclosing the problem are: youth unemployment, the tendencies of secondary vocational education, proportions of enrollment and the features of training tendencies, the growing number of early dropouts, the effect of family background on student performance. This work tried to find the answer to the question: What variations have the changes in the regulations of vocational training, encouraging dual education brought on in the connection between trainers and work places? The research did not prove that the central vocational training system would be more effective than a varied, flexible, permeable, transparent decentralized operation with parts built on each other. The introduction of the complex exam overshadowed the evaluation of the competency areas, and fits less to the modularity of the framework curricula. With the legal regulation of vocational training in force the modular system has become a formality. Taking prior knowledge into account has become more difficult. The efficiency of professional structural decisions is questionable, it has not triggered the extension of employment among career starters, and does not mean a guarantee of finding a job either. Creating the motivation of economic role players may bring on steps forward to take up bigger tasks in vocational training. The research has confirmed the importance of improving the basic competency areas when planning vocational training, of life-long learning, of practice orientation, and also of the continuous connection with the labor market.

  2. Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice

    Science.gov (United States)

    2014-01-01

    Introduction Previous observations implicate Indian hedgehog (Ihh) signaling in osteoarthritis (OA) development because it regulates chondrocyte hypertrophy and matrix metallopeptidase 13 (MMP-13) expression. However, there is no direct genetic evidence for the role of Ihh in OA, because mice with cartilage or other tissue-specific deletion of the Ihh gene die shortly after birth. We evaluated the role of Ihh in vivo via a Cre-loxP-mediated approach to circumvent the early death caused by Ihh deficiency. Methods To evaluate the role of Ihh in OA development, Ihh was specifically deleted in murine cartilage using an Ihh conditional deletion construct (Col2a1-CreERT2; Ihhfl/fl). The extent of cartilage degradation and OA progression after Ihh deletion was assessed by histological analysis, immunohistochemistry, real-time PCR and in vivo fluorescence molecular tomography (FMT) 2 months after OA was induced by partial medial meniscectomy. The effect of Ihh signaling on cartilage was compared between Ihh-deleted mice and their control littermates. Results Only mild OA changes were observed in Ihh-deleted mice, while control mice displayed significantly more cartilage damage. Typical OA markers such as type X collagen and MMP-13 were decreased in Ihh-deleted mice. In vivo FMT demonstrated decreased cathepsins and MMP activity in knee joints of animals with deletion of Ihh. Conclusions These findings support the protective role of Ihh deletion in surgically induced OA. Thus, our findings suggest the potential to develop new therapeutic strategies that can prevent and treat OA by inhibiting Ihh signaling in chondrocytes. PMID:24428864

  3. Vocational Education and Economic Development in Nigeria | Ekpo ...

    African Journals Online (AJOL)

    This paper discusses the capability of vocational education in creating jobs to reduce unemployment among the Nigerian youths which will result in sustainable economic development of Nigeria. It also defines Vocational education within the provisions of the National Policy on Education. Philosophy of Vocational ...

  4. Schools and Work: Developments in Vocational Education. Cassell Education Series.

    Science.gov (United States)

    Coffey, David

    This book assesses the developing vocational functions of schools in Britain, identifies vocational values and policies, and discovers gaps in provision. Chapter 1 gives a summary analysis of school structural and curricular developments between medieval times and the reign of Victoria that were inspired by vocational or economic influences or had…

  5. Cognitive Structures in Vocational Information Processing and Decision Making.

    Science.gov (United States)

    Nevill, Dorothy D.; And Others

    1986-01-01

    Tested the assumptions that the structural features of vocational schemas affect vocational information processing and career self-efficacy. Results indicated that effective vocational information processing was facilitated by well-integrated systems that processed information along fewer dimensions. The importance of schematic organization on the…

  6. The Narrative Process of Improving Vocational Classroom Practice

    Science.gov (United States)

    Sharman, Kathleen Y.

    2011-01-01

    This research inquires into the use of stories by vocational teachers. These stories are of interest because they are a fundamental feature of both the subject content and the social structures of vocational classrooms. The trade experiences of vocational teachers are brought to the classroom through stories. These stories have a secondary effect…

  7. Vocational Profiles and Internship Quality among Portuguese VET Students

    Science.gov (United States)

    Gamboa, Vitor; Paixão, Maria Paula; de Jesus, Saúl Neves

    2014-01-01

    The provision of workplace-based experiences (internships) is an important component of the training program for students attending vocational education courses. The purpose of this study was to clarify the relationship between internship quality and students vocational development, considering students' vocational profiles, in a sample of 346…

  8. Safety Standards Plan for Middlesex County Vocational & Technical High Schools.

    Science.gov (United States)

    Sommer, Cy

    This vocational education safety standards plan outlines rules and regulations adopted by the Board of Education of Middlesex County Vocational and Technical High Schools. The first of eleven chapters presents demographics and a safety organization table for Middlesex County Vocational and Technical Schools. In chapter 2, six safety program…

  9. Reasons for Entering College and Academic and Vocational Preferences.

    Science.gov (United States)

    Gordon, Virginia N.

    1982-01-01

    Explored the relationships between students' (N=305) reasons for enrolling in college as measured by the Educational Participation Scale and their vocational and educational preferences as measured by the Vocational Preference Inventory. Results suggested relationships may exist between students' educational and vocational preferences and…

  10. Professional Identities of Vocational High School Students and Extracurricular Activities

    Science.gov (United States)

    Altan, Bilge Aslan; Altintas, Havva Ozge

    2017-01-01

    Vocational high schools are one of the controversial topics, and also the hardly touched fields in educational field. Students' profiles of vocational schools, their visions, and professional identity developments are not frequently reflected in the literature. Therefore, the main aim of the study is to research whether vocational high school…

  11. Closing the Gap. SREB Program Blends Academic Standards, Vocational Courses.

    Science.gov (United States)

    Bottoms, Gene

    1992-01-01

    Southern Regional Education Board's State Vocational Education Consortium developed a model for integrating vocational and academic education that includes at least three credits each in math and science; four English courses; and four credits in a vocational major and two in related fields. Eight sites implementing the model have narrowed gap…

  12. Working Partnerships: A Joint Venture in Vocational Education.

    Science.gov (United States)

    Campbell, Clifton P.

    Joint Ventures in Vocational Education projects link participating businesses with secondary vocational programs in a cooperative relationship. These are voluntary arrangements between vocational programs and a public or private sector agency that combine the energies and resources of the partners to enrich various aspects of the vocational…

  13. Erik Erikson's Theory of Psychosocial Development and Vocational Behavior

    Science.gov (United States)

    Munley, Patrick H.

    1975-01-01

    Stage resolution attitudes, derived from the first six stage crises outlined by Erikson, were explored as variables influencing problems in vocational choice and vocational maturity. Findings indicated students who made adjusted vocational choices and developed mature career attitudes had also been more successful resolving the first six…

  14. Finnish vocational education and training in comparison: Strengths and weaknesses

    Directory of Open Access Journals (Sweden)

    Maarit Virolainen

    2014-12-01

    Full Text Available The study investigates how the Finnish model of providing initial vocational education and training (IVET has succeeded in terms of enhancing educational progress and employability. A relatively high level of participation in IVET makes the Finnish model distinctive from those of three other Nordic countries: Denmark, Norway and Sweden. All four Nordic countries have wellorganised labour markets and universal types of welfare states. Priority is given to goals related to equal opportunities and social inclusion. At the same time, these countries have different models of IVET. While the study compares the Finnish model of organising IVET to those of other Nordic countries, it also examines the German and UK models, which represent differing societal approaches to IVET. The differences in the outcomes of the IVET systems are described and analysed through reviewing secondary data provided by Eurydice and Eurostat, along with country reports produced in a Nordic comparative project, Nord-VET.

  15. Vocation in theology-based nursing theories.

    Science.gov (United States)

    Lundmark, Mikael

    2007-11-01

    By using the concepts of intrinsicality/extrinsicality as analytic tools, the theology-based nursing theories of Ann Bradshaw and Katie Eriksson are analyzed regarding their explicit and/or implicit understanding of vocation as a motivational factor for nursing. The results show that both theories view intrinsic values as guarantees against reducing nursing practice to mechanistic applications of techniques and as being a way of reinforcing a high ethical standard. The theories explicitly (Bradshaw) or implicitly (Eriksson) advocate a vocational understanding of nursing as being essential for nursing theories. Eriksson's theory has a potential for conceptualizing an understanding of extrinsic and intrinsic motivational factors for nursing but one weakness in the theory could be the risk of slipping over to moral judgments where intrinsic factors are valued as being superior to extrinsic. Bradshaw's theory is more complex and explicit in understanding the concept of vocation and is theologically more plausible, although also more confessional.

  16. Workplace-based assessment for vocational registration of international medical graduates.

    Science.gov (United States)

    Lillis, Steven; Van Dyk, Valencia

    2014-01-01

    Medical regulatory authorities need efficient and effective methods of ensuring the competence of immigrating international medical graduates (IMGs). Not all IMGs who apply for specialist vocational registration will have directly comparable qualifications to those usually accepted. As general licensure examinations are inappropriate for these doctors, workplace-based assessment (WBA) techniques would appear to provide a solution. However, there is little published data on such outcomes. All cases of WBA (n = 81) used for vocational registration of IMGs in New Zealand between 2008 and 2013 were collated and analyzed. The successful completion rate of IMGs through the pathway was 87%. The majority (64%) undertook the year of supervised practice and the final assessment in a provincial center. For those unsuccessful in the pathway, inadequate clinical knowledge was the most common deficit found, followed by poor clinical reasoning. A WBA approach for assessing readiness of IMGs for vocational registration is feasible. The constructivist theoretical perspective of WBA has particular advantages in assessing the standard of practice for experienced practitioners working in narrow scopes than traditional methods of assessment. The majority of IMGs undertook both the clinical year and the assessment in provincial hospitals, thus providing a workforce for underserved areas. © 2014 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on Continuing Medical Education, Association for Hospital Medical Education.

  17. The EC Discourse on Vocational Training: How a "Common Vocational Training Policy" Turned into a Lifelong Learning Strategy

    Science.gov (United States)

    Cort, Pia

    2009-01-01

    This article traces the EC vocational training policy historically and describes the discursive alignments which brought the policy from a "common vocational training policy" as laid down in Article 128, in the Treaty of Rome to the Lisbon Lifelong Learning strategy. The argument is that vocational training has served as a lever for the…

  18. Vocational Teaching-Learning through the Eyes of Undergraduate Vocational Students in Malta: A Qualitative Exploratory Study

    Science.gov (United States)

    Said, Alison

    2018-01-01

    The purpose of this study is to develop a deeper understanding of the teaching qualities of effective lecturers that vocational students desire, students assessment preferences and preferred learning environments. This study gives a voice to higher vocational students as it is important for vocational educators to learn what attracts students to…

  19. The Effects of Vocational Leadership Development for Individuals Who Participated in the Ohio Vocational Education Leadership Institute.

    Science.gov (United States)

    Leimbach, Gale John

    The effects of vocational leadership development were studied for 23 Fellows enrolled in the 1992 Ohio Vocational Education Leadership Institute (OVELI). A literature review focused on four components: leadership styles, educational leadership development, vocational leadership development, and visionary leadership development. The Leadership…

  20. Students’ meaning-making and sense-making of vocational knowledge in Dutch senior secondary vocational education

    NARCIS (Netherlands)

    Nienke Bijlsma; Harmen Schaap; Prof.Dr. Elly de Bruijn

    2016-01-01

    Meaning-making and sense-making are generally assumed to be part of students’ personal vocational knowledge development, since they contribute to both students’ socialisation in a vocation and students’ personalisation of concepts, values and beliefs regarding that vocation. However, how students in

  1. An Educational–Vocational Intervention

    Directory of Open Access Journals (Sweden)

    Kalervo Friberg

    2013-07-01

    Full Text Available Changes in student-affective entry characteristics were examined in an educational−vocational intervention at Finnish comprehensive school. The conceptual framework constructed from attitudes as learned dispositions (Fishbein & Ajzen, 1975 and self-determination (Deci & Ryan, 1985 was tested in a longitudinal study. A person-based survey questionnaire was designed, piloted, and validated. Spearman−Brown reliability was calculated. In the first observation, 669 (Time One Cohort, and in the second, 649 (Time Two Cohort subjects (girls and boys of mean ages of 14.5 and 16.0 years took the Web-based survey. The tested hypotheses were (a variables of self-determination, self-regulation, and intrinsic and extrinsic motivation would emerge as attitudinal domains in work−life orientation; (b the experiences during the implementation of a work−life orientation program would decrease the effects of seventh-grade student background factors at the end of the program in the ninth grade, and (c work−life orientation would be effective and have efficacy in changing student attitudes in relation to further education and occupations. Three factors emerged in the Maximum Likelihood Factor Analysis. The factors Independence, Self-Direction, and Flexibility were used as the dependents in repeated measures in a general linear model. The factor means were subjected to a paired samples t test. There was development toward stronger Independence and Flexibility in the case of both genders. The boys had gained the girls’ seventh-grade lead at the end of the program. Self-Direction did not show any changes. Empirical findings tentatively supported the program’s efficacy in changing entry characteristics.

  2. Coagulation factor VIIa-mediated protease-activated receptor 2 activation leads to β-catenin accumulation via the AKT/GSK3β pathway and contributes to breast cancer progression.

    Science.gov (United States)

    Roy, Abhishek; Ansari, Shabbir A; Das, Kaushik; Prasad, Ramesh; Bhattacharya, Anindita; Mallik, Suman; Mukherjee, Ashis; Sen, Prosenjit

    2017-08-18

    Cell migration and invasion are very characteristic features of cancer cells that promote metastasis, which is one of the most common causes of mortality among cancer patients. Emerging evidence has shown that coagulation factors can directly mediate cancer-associated complications either by enhancing thrombus formation or by initiating various signaling events leading to metastatic cancer progression. It is well established that, apart from its distinct role in blood coagulation, coagulation factor FVIIa enhances aggressive behaviors of breast cancer cells, but the underlying signaling mechanisms still remain elusive. To this end, we investigated FVIIa's role in the migration and invasiveness of the breast cancer cell line MDA-MB-231. Consistent with previous observations, we observed that FVIIa increased the migratory and invasive potential of these cells. We also provide molecular evidence that protease-activated receptor 2 activation followed by PI3K-AKT activation and GSK3β inactivation is involved in these processes and that β-catenin, a well known tumor-regulatory protein, contributes to this signaling pathway. The pivotal role of β-catenin was further indicated by the up-regulation of its downstream targets cyclin D1, c-Myc, COX-2, MMP-7, MMP-14, and Claudin-1. β-Catenin knockdown almost completely attenuated the FVIIa-induced enhancement of breast cancer migration and invasion. These findings provide a new perspective to counteract the invasive behavior of breast cancer, indicating that blocking PI3K-AKT pathway-dependent β-catenin accumulation may represent a potential therapeutic approach to control breast cancer. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. Reforming vocational didactics by implementing a new VET teacher education

    DEFF Research Database (Denmark)

    Duch, Henriette; Andreasen, Karen Egedal

    2015-01-01

    from backgrounds with no tradition for education. Despite historical changes, the education as vocational college teacher also struggles with the interplay between theory and practice in the program and great diversity among vocational college teachers. Based on empirical data from focus group......A new education program, Diploma of Vocational Pedagogy, has recently been implemented in Denmark to upskill vocational college teachers and improve didactics at VET colleges in general. Among many challenges, vocational college teachers have to adapt their pedagogy to a large number of students...... interviews with students from the Diploma of Vocational Pedagogy program and concepts developed by Bernstein and Bourdieu, the article analyzes how these aspects might affect the development of new vocational didactics. We know that it is not easy to change the culture of educational institutions...

  4. Student performance and satisfaction in continuous learning pathways in Dutch VET

    NARCIS (Netherlands)

    Biemans, H.J.A.

    2012-01-01

    An important trend in the Vocational Education and Training (VET) system in the Netherlands is the design of continuous learning pathways enclosing more than one school type level. These continuous learning pathways are characterized by different design formats. In this study, the relations between

  5. Secondary Vocational Horticulture Programs--An Assessment.

    Science.gov (United States)

    Burnett, Michael F.; Smith, Charles W.

    1983-01-01

    The objectives of the study were to determine characteristics of secondary horticulture teachers, the structure of horticulture departments, funding sources, nature and scope of facilities, types of supervised occupational experience programs in which horticulture students participated, and curriculum characteristics of vocational horticulture…

  6. EDUCATION AND VOCATIONAL TRAINING OF TEC CLAIMANTS.

    Science.gov (United States)

    Indiana State Employment Security Div., Indianapolis.

    TO COLLECT INFORMATION CONCERNING THE PERSONAL CHARACTERISTICS, FAMILY STATUS, EDUCATION AND VOCATIONAL TRAINING, WORK HISTORY, AND UNEMPLOYMENT EXPERIENCE OF TEMPORARY EXTENDED UNEMPLOYMENT COMPENSATION (TEC) CLAIMANTS IN INDIANA, A QUESTIONNAIRE-INTERVIEW WAS ADMINISTERED TO A 5 PERCENT SAMPLE OF PERSONS FILING CLAIMS DURING 3 SELECTED WEEKS,…

  7. Coping Styles of Failing Brunei Vocational Students

    Science.gov (United States)

    Mundia, Lawrence; Salleh, Sallimah

    2017-01-01

    Purpose: The purpose of this paper is to determine the prevalence of two types of underachieving students (n = 246) (active failing (AF) and passive failing (PF)) in Brunei vocational and technical education (VTE) institutions and their patterns of coping. Design/methodology/approach: The field survey method was used to directly reach many…

  8. Desiderata: Towards Indigenous Models of Vocational Psychology

    Science.gov (United States)

    Leong, Frederick T. L.; Pearce, Marina

    2011-01-01

    As a result of a relative lack of cross-cultural validity in most current (Western) psychological models, indigenous models of psychology have recently become a popular approach for understanding behaviour in specific cultures. Such models would be valuable to vocational psychology research with culturally diverse populations. Problems facing…

  9. Vocational and Technical Education Reform in Turkey

    Science.gov (United States)

    Kilic, Abdurrahman

    2006-01-01

    Turkey is a country where individual rights and freedom of people are improving. It is known that a free market economy is in its infancy. There is a strong relationship between developed human resources and the production sector. In this sense, vocational and technical education is very important. It cannot be said that the efforts for…

  10. Vocational and Technical Education in Peru.

    Science.gov (United States)

    Bellew, Rosemary; Moock, Peter

    1990-01-01

    This cost-benefit analysis of Peruvian vocational and technical education (VTE) partly substantiates previous research suggesting that VTE in developing countries fails to offer a return commensurate with its cost. The costs of academic and VTE streams in Peru are similar, and graduates' monetary returns and occupational profiles are almost…

  11. Individual Predictors of Adolescents' Vocational Interest Stabilities

    Science.gov (United States)

    Hirschi, Andreas

    2010-01-01

    The study investigated the predictive utility of interest profile differentiation, coherence, elevation, congruence, and vocational identity commitment and career maturity (career planning and exploration) on the 10-month interest stability of 292 Swiss eighth-grade students: profile, rank, and level stabilities were assessed. Controlling for…

  12. Profiling Religious Fundamentalism's Associations with Vocational Interests

    Science.gov (United States)

    Warlick, Craig A.; Ingram, Paul B.; Multon, Karen D.; Vuyk, M. Alexandra

    2017-01-01

    Religion is a shaping force in the world today, increasingly expressed and integral to the flow and function of the workplace. The relationship between religious identity and work function is clearly present. However, no lines of research have explored how religion explains the variations in vocational interest, despite speculation that it does…

  13. Modularisation and Vocational Education in Scotland.

    Science.gov (United States)

    Thomson, Sandy

    In Scotland, vocational education at the professional level takes place in colleges and universities and at the craft and technician level, in further education colleges. Most of the further education/higher education curriculum has been modularized. The following benefits of modularization are claimed: rationalization of resource provision;…

  14. Career conversations in senior secondary vocational education

    NARCIS (Netherlands)

    Mittendorff, K.M.

    2010-01-01

    In the Netherlands, many schools for senior secondary vocational education are implementing competence-based curricula. These curricula start from a constructivist approach and are based on the idea that young people should learn to reflect on their personal ambitions and motives, and to undertake

  15. Business Enterprise Program | Division of Vocational Rehabilitation

    Science.gov (United States)

    About Us > Business Enterprise Program Business Enterprise Program The Division of Vocational Rehabilitation's (DVR) Business Enterprise Program (BEP) provides employment opportunities to people who experience contact their DVR counselor or the BEP coordinator. List of Business Enterprise Program Vendors BEP Policy

  16. Vocational Education and Learning in Higher Education

    Science.gov (United States)

    de Carvalho, Cynthia Paes

    2012-01-01

    This article discusses the relationship of students with learning and the university in the context of current challenges to vocational education and economic development. Inspired by the research of Pierre Bourdieu, this case study focuses on the relationship of students to learning and the university in Brazil. The survey gathered elements that…

  17. A Paradoxical Approach to Vocational Indecision.

    Science.gov (United States)

    Lopez, Frederick G.

    1983-01-01

    Describes a case study in which a paradoxical intervention was effectively used in treating a vocationally indecisive college student and his overly involved father. The quality of the father-son interaction improved as the student's anxiety decreased. Implications for the use of paradox in other situations are discussed. (Author/JAC)

  18. Vocational Education Institutions' Role in National Innovation

    Science.gov (United States)

    Moodie, Gavin

    2006-01-01

    This article distinguishes research--the discovery of new knowledge--from innovation, which is understood to be the transformation of practice in a community or the incorporation of existing knowledge into economic activity. From a survey of roles served by vocational education institutions in a number of OECD countries the paper argues that…

  19. Vocational Education: A Social Anarchist Perspective

    Science.gov (United States)

    Suissa, Judith

    2004-01-01

    This article discusses the social anarchist tradition of educational thought and practice, in order to throw new light on the philosophical discussion of the liberal-vocational distinction. Focusing on the central anarchist idea of integral education, I argue that the political stance of social anarchism is inseparable from the educational ideas…

  20. Food Service Course. Bilingual Vocational Instructional Materials.

    Science.gov (United States)

    Lopez-Cox, Guadalupe

    This course in food services, one of a series of bilingual English-Spanish vocational education courses, is designed to familiarize the student with the food service operation of a restaurant, cafeteria, fast-food operation, hospital, nursing home, industrial or educational facility, food caterer, or bakery. The student should become versatile in…

  1. Ordinal Position Research Related to Vocational Interest

    Science.gov (United States)

    Gandy, Gerald L.

    1974-01-01

    Birth order studies directly related to vocational interest were reviewed to discern support for certain theoretical susumptions: firstborns are more directing, controlling, and organizing than later borns and later borns are more sociable, empathic, and sympathetic than firstborns. The research was inconsistent, contradictory, and speculative.…

  2. Complexity in Vocational Education and Training Governance

    Science.gov (United States)

    Oliver, Damian

    2010-01-01

    Complexity is a feature common to all vocational education and training (VET) governance arrangements, due to the wide range of students VET systems caters for, and the number of stakeholders involved in both decision making and funding and financing. In this article, Pierre and Peter's framework of governance is used to examine complexity in VET…

  3. Reforms and innovations in Nordic vocational education:

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    2018-01-01

    The chapter examines policy reforms and innovations in the Nordic vocational education and training systems (VET) related to two challenges. The first is to improve the links of the VET system to the labour market and to ease the students’ transition to employment. It examines three new types...

  4. Decision-Making Style and Vocational Maturity.

    Science.gov (United States)

    Phillips, Susan D.; Strohmer, Douglas C.

    1982-01-01

    Examined the relationship between decision-making style, scholastic achievement, and vocational maturity for college students (N=64). Results did not support the hypothesized relationship between rationality and attitudinal and cognitive maturity. Scholastic achievement and lack of dependent decision style were found to be moderately predictive of…

  5. Are Graduates Preferred to Those Completing Initial Vocational Education and Training? Case Studies on Company Recruitment Strategies in Germany, England and Switzerland

    Science.gov (United States)

    Hippach-Schneider, Ute; Weigel, Tanja; Brown, Alan; Gonon, Philipp

    2013-01-01

    The German and Swiss economies value skilled work highly and initial vocational education and training (IVET) has been the predominant traditional pathway into such work. However, concerns about a more "knowledge-based society" and the "academic shift in the labour market" are starting to undermine the status associated with…

  6. Updating the Wnt pathways

    Science.gov (United States)

    Yu, Jia; Virshup, David M.

    2014-01-01

    In the three decades since the discovery of the Wnt1 proto-oncogene in virus-induced mouse mammary tumours, our understanding of the signalling pathways that are regulated by the Wnt proteins has progressively expanded. Wnts are involved in an complex signalling network that governs multiple biological processes and cross-talk with multiple additional signalling cascades, including the Notch, FGF (fibroblast growth factor), SHH (Sonic hedgehog), EGF (epidermal growth factor) and Hippo pathways. The Wnt signalling pathway also illustrates the link between abnormal regulation of the developmental processes and disease manifestation. Here we provide an overview of Wnt-regulated signalling cascades and highlight recent advances. We focus on new findings regarding the dedicated Wnt production and secretion pathway with potential therapeutic targets that might be beneficial for patients with Wnt-related diseases. PMID:25208913

  7. Vocational Guidance for Equal Access and Opportunity for Girls and Women in Technical and Vocational Education. UNEVOC Studies in Technical and Vocational Education 6.

    Science.gov (United States)

    Miller, Juliet V.; Vetter, Louise

    A study examined the relevance of vocational information and guidance for the equal access of girls and women to technical/vocational education in the following countries: Argentina; India; Mexico; Republic of Korea; South Africa; Spain; Sweden; Turkey; United Arab Emirates; and Zambia. Case studies were conducted by using a multiple-strategy…

  8. Vocational Teachers and Professionalism - A Model Based on Empirical Analyses

    DEFF Research Database (Denmark)

    Duch, Henriette Skjærbæk; Andreasen, Karen E

    Vocational Teachers and Professionalism - A Model Based on Empirical Analyses Several theorists has developed models to illustrate the processes of adult learning and professional development (e.g. Illeris, Argyris, Engeström; Wahlgren & Aarkorg, Kolb and Wenger). Models can sometimes be criticized...... emphasis on the adult employee, the organization, its surroundings as well as other contextual factors. Our concern is adult vocational teachers attending a pedagogical course and teaching at vocational colleges. The aim of the paper is to discuss different models and develop a model concerning teachers...... at vocational colleges based on empirical data in a specific context, vocational teacher-training course in Denmark. By offering a basis and concepts for analysis of practice such model is meant to support the development of vocational teachers’ professionalism at courses and in organizational contexts...

  9. A cultural turn? Vocational teacher education in Denmark

    DEFF Research Database (Denmark)

    Duch, Henriette

    actors in the field. The actors had different interests, which is also visible in documents. The analysis reveals three main discussions. The first is the loss of ‘situated learning’ or vocational teacher training in vocational colleges. The second is theory of science as a symbol of academization......As part of my Ph.D.-project the field of educational policy is analysed with a focus on the decision process on a change of vocational teacher education (Bourdieu, 1996; Duch and Rasmussen, XX). The process is seen in the light of the Bologna process. Originally, the education of Danish vocational...... teachers was a specialized and non-classified course, now it is classifies as a higher education at level six in the Danish Qualification Framework. The analysis is based on qualitative interviews with representatives of for example vocational teachers and of leaders at vocational colleges – different...

  10. he (UnAttractiveness of Vocational and Technical Education: Theoretical Background

    Directory of Open Access Journals (Sweden)

    Miha Lovšin

    2014-03-01

    Full Text Available This paper considers the problem of the lack of attractiveness of vocational and technical education via a review of legislation on counselling practices, implementing documents, and the social factors by means of which the education system can influence the individual’s decision. It is apparent that legislation regulating the organisation and content of career counselling services in educational sector is inadequate. The organisation of career counselling at the level of implementation is also inadequate. Counsellors advise individuals on the basis of their academic results and the results of aptitude tests. Counselling practices deriving from theories that place career planning and management skills in the foreground are more rarely represented. Theories that treat career decisions as a social process show that at the level of the student population the choice of the type of school is a rational decision based primarily on the economic position and level of education to which a specific educational pathway is generally supposed to lead. The lower attractiveness of vocational and technical education coincides with the fact that representatives of lower social classes have a weaker economic position and more frequently have vocational and technical education qualifications than representatives of higher social classes. Nevertheless, the trend of high unemployment among young people with academic qualifications, which opposite of the traditional situation, indicates that it will be necessary to include career planning and management skills in the educational contents of institutionalised and formal education as a whole.

  11. Physical education candidate teachers' beliefs about vocational self-esteem

    OpenAIRE

    OZSAKER, Murat; CANPOLAT, A. Meliha

    2014-01-01

    The purpose of this study was to determine epistemological belief and vocational self-esteem physical education candidate teachers of Physical Education and Sports Department in 3 different universities, and also to examine effect of epistemological beliefs on vocational self-esteem. A total of 346 candidate teacher respondents (137 female and 209 male) participated in the study. Epistemological Beliefs and Vocational Self-Esteem Scale were used to determine candidate teachers’ epistemologica...

  12. Students’ Preferred Characteristics of Learning Environments in Vocational Secondary Education

    OpenAIRE

    Ingeborg Placklé; Karen D. Könings; Wolfgang Jacquet; Katrien Struyven; Arno Libotton; Jeroen J. G. van Merriënboer; Nadine Engels

    2014-01-01

    If teachers and teacher educators are willing to support the learning of students, it is important for them to learn what motivates students to engage in learning. Students have their own preferences on design characteristics of powerful learning environments in vocational education. We developed an instrument – the Inventory Powerful Learning Environments in Vocational Education - to measure students’ preferences on characteristics of powerful learning environments in vocational education. W...

  13. Students Preferred Characteristics of Learning Environments in Vocational Secondary Education

    OpenAIRE

    Placklé, Ingeborg

    2014-01-01

    If teachers and teacher educators are willing to support the learning of students, it is important for them to learn what motivates students to engage in learning. Students have their own preferences on design characteristics of powerful learning environments in vocational education. We developed an instrument - the Inventory Powerful Learning Environments in Vocational Education - to measure studentsâ preferences on characteristics of powerful learning environments in voca-tional education. ...

  14. Vocatives and Other Direct Address Forms: A Contrastive Study

    OpenAIRE

    Lilli Parrott

    2010-01-01

    In this paper I analyze Russian direct address forms, both the distinct truncated vocative and nominative-case direct address forms. I contrast the formal and functional restrictions on the truncated vocative with vocatives in other languages (e.g. Czech and Polish), and I compare the interpolation of Russian direct address forms in an utterance to the situation in English. While similarities are found both in the form and the usage of Russian direct address forms with those in other language...

  15. Vocational Students’ Motivation for Professional Skills

    Science.gov (United States)

    Sojow, L.; Wajong, A.; Sangi, N.

    2018-02-01

    The purpose of this research is to know whether there is a positive and significant correlation between readiness work and achievement motivation with performance of vocational education graduates. Expost facto research method by taking data with instrument was employed in this study. To obtain data on work attitude variables, achievement motivation is taken from primary data through employee respondents in Bitung City, Indonesia industry with a sample of 37 people. Results of the research show that: (i) good work readiness is the dominant element in determining the performance level of vocational graduate worker. (ii) There is correlation between achievement motivation with graduate performance, (iii) there is correlation between work readiness and achievement motivation together with graduate performance. The contribution of work readiness and achievement motivation together with graduate performance was 73%.

  16. Wellbeing and smoking at Danish vocational schools

    DEFF Research Database (Denmark)

    Andersen, Susan; Rod, Morten Hulvej; Ersbøll, Annette Kjær

    2017-01-01

    at baseline the intervention was associated with lower odds (OR=0.44, 95% CI=0.22-0.86) of daily smoking at follow-up.Conclusion Shaping the Social had positive effects on school connectedness. Moreover, the intervention was effective in preventing occasional smokers to become daily smokers. The study......, there is a need for more evidence-based intervention programs. The aim of this study was to assess the effectiveness of a settings-based intervention (Shaping the Social) at vocational schools on student wellbeing and smoking.MethodsWe employed a non-randomized controlled trial of 5794 students (mean age 21 years......; 81% male) in 10 (four intervention and six comparison) large vocational schools in Denmark. The intervention integrated social activities with professional learning and focused on four themes: introduction activities; daily class meetings; scheduled breaks; creating a pleasant non-smoking environment...

  17. Wellbeing and smoking at Danish vocational schools

    DEFF Research Database (Denmark)

    Andersen, Susan; Rod, Morten Hulvej; Ersbøll, Annette Kjær

    occasional smokers at baseline the intervention was associated with lower odds (OR=0.44, 95% CI=0.22-0.86) of daily smoking at follow-up. Conclusion Shaping the Social had positive effects on school connectedness. Moreover, the intervention was effective in preventing occasional smokers to become daily......, there is a need for more evidence-based intervention programs. The aim of this study was to assess the effectiveness of a settings-based intervention (Shaping the Social) at vocational schools on student wellbeing and smoking. Methods We employed a non-randomized controlled trial of 5794 students (mean age 21...... years; 81% male) in 10 (four intervention and six comparison) large vocational schools in Denmark. The intervention integrated social activities with professional learning and focused on four themes: introduction activities; daily class meetings; scheduled breaks; creating a pleasant non-smoking...

  18. Vocational interest evaluation of TMR adults.

    Science.gov (United States)

    Becker, R L; Schull, C; Cambell, K

    1981-01-01

    Fifty TMR adults participated in a three-stage job-training and placement program over a 5-year period. Vocational inventoried interest and expressed interest were correlated, as were relationships between inventoried interest and such variables as CA and IQ. The results showed that (a) TMR adults can discriminate between occupational likes and dislikes when using pictorial inventoried interest assessment techniques, (b) a positive relationship exists between expressed and inventoried interest, (c) inventoried interest is independent of CA and IQ, (d) there was a general consistency in inventoried occupational choice over a 6-month interval, and (e) the Reading-Free Vocational Interest Inventory has predictive and status validity, as evidenced by job incumbents' success and their inventory cluster profiles.

  19. Design of Trigonometry Apps for Vocational Education

    DEFF Research Database (Denmark)

    Pedersen, Jens Bjarke; Andersen, Steffen; Majgaard, Gunver

    2012-01-01

    How can smartphones apps enrich the learning of mathematicsin vocational education? This article examines how mathematics teaching can be enriched by apps using smartphone sensors such as gyroscope, compass, camera, and touch screen in a aming context. An iterative and participatory design process.......The combination of competition to unlock exercises, competition for placing on the high-score list, and physical activity proved very motivating for the students and was also approved by their teachers. In this article we describe our design principles, the overall game architecture and the games themselves. We...... talk about our experience in implementing our design process and subsequently summarize the pros and cons of the application and the smartphone platform and how the app developed contributes to vocational mathematics teaching....

  20. Relationship between personality traits and vocational choice.

    Science.gov (United States)

    Garcia-Sedeño, Manuel; Navarro, Jose I; Menacho, Inmaculada

    2009-10-01

    Summary.-The relationship between occupational preferences and personality traits was examined. A randomly chosen sample of 735 students (age range = 17 to 23 years; 50.5% male) in their last year of high school participated in this study. Participants completed Cattell's Sixteen Personality Factor-5 Questionnaire (16PF-5 Questionnaire) and the Kuder-C Professional Tendencies Questionnaire. Initial hierarchical cluster analysis categorized the participants into two groups by Kuder-C vocational factors: one showed a predilection for scientific or technological careers and the other a bias toward the humanities and social sciences. Based on these groupings, differences in 16PF-5 personality traits were analyzed and differences associated with three first-order personality traits (warmth, dominance, and sensitivity), three second-order factors (extraversion, control, and independence), and some areas of professional interest (mechanical, arithmetical artistic, persuasive, and welfare) were identified. The data indicated that there was congruency between personality profiles and vocational interests.

  1. Challenges in professional bachelor and vocational programmes

    DEFF Research Database (Denmark)

    Knudsen, Lars Emmerik Damgaard

    2015-01-01

    between theory and practice, and a relatively high retention rate and hence a public debate of the reasons why. The issues of transitions, retention of theory and practice relations constitute what could be called a “problematique of the professional bachelor and vocational programmes”. A problematique...... in another historically but longer lasting perspective; the issue of theory and practice. These knowledge forms run through all the programmes at issue, and the general expectation is that theory and practice relations are coherently organized by the educational institutions and acquired by the students......This special issue is devoted to the challenges of professional bachelor and vocational programmes in Norway and Denmark. Both forms of educational programmes are characterized by students' transitions between college and placement, difficulties at sustaining students' experience of coherence...

  2. Benchmarking Danish Vocational Education and Training Programmes

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wittrup, Jesper

    . This makes it difficult to compare the resources used, since some programmes by their nature require more classroom time and equipment than others. It is also far from straightforward to compare college effects with respect to grades, since the various programmes apply very different forms of assessment....... In addition to these conceptual challenges, analyses of vocational colleges present problems with respect to data. It is difficult in many cases to be certain of the correspondences between resources used and student-related factors, since students are registered at a college level, while resources used...... are recorded at a higher level, i.e. that of umbrella institutions administering programmes at several colleges. In this study paper, analyses are restricted to around 40 vocational colleges where it was possible to be certain of the correspondence between resource use and student-related achievement. We...

  3. Vocational and technical education in Peru

    OpenAIRE

    Moock, Peter; Bellew, Rosemary

    1988-01-01

    The relative costs of and returns to VTE (Vocational and Technical Education) and general education in Peru are investigated here. The paper is composed as follows. Following a brief introduction, section 2 describes the system of education in Peru and changes that have occurred in this system over time. Section 3 surveys the (relatively sparse) literature on comparative rates of return to VTE and general education. Sections 4 and 5 describe, respectively, the data used for this study and the...

  4. LEADERSHIP IN TECHNICAL AND VOCATIONAL EDUCATION

    OpenAIRE

    Jamaluddin Hashim; Baharom Mohamad; Kamarolzaman Md. Jidi; Ramlan Zainal Abidin; Hussein Junoh

    2010-01-01

    Good leadership in the lifelong learning of technical and vocational education exists when the leaders are able to perform either one or combination of transformational leadership characteristics, even though, less emphasis on these characteristics can affect job satisfaction of his or her subordinates. This study investigated transformational of Heads of Departments at the Polytechnics with regards to the job satisfaction of the lecturers. Respondents of this study are made up of 365 lecture...

  5. Vocational teaching-learning through the eyes of undergraduate vocational students in Malta: A qualitative exploratory study

    OpenAIRE

    Said, Alison

    2018-01-01

    The purpose of this study is to develop a deeper understanding of the teaching qualities of effective lecturers that vocational students desire, students assessment preferences and preferred learning environments. This study gives a voice to higher vocational students as it is important for vocational educators to learn what attracts students to effective learning. Due to the inquiry's exploratory nature, an interpretivist approach was used, and a constructivist grounded approach using qualit...

  6. Vocational Teaching-Learning through the Eyes of Undergraduate Vocational Students in Malta: A Qualitative Exploratory Study

    OpenAIRE

    Alison Said

    2018-01-01

    The purpose of this study is to develop a deeper understanding of the teaching qualities of effective lecturers that vocational students desire, students assessment preferences and preferred learning environments. This study gives a voice to higher vocational students as it is important for vocational educators to learn what attracts students to effective learning. Due to the inquiry’s exploratory nature, an interpretivist approach was used, and a constructivist grounded approach using qualit...

  7. Vocational teaching-learning through the eyes of undergraduate vocational students in Malta: a qualitative exploratory study

    OpenAIRE

    Said, Alison

    2018-01-01

    The purpose of this study is to develop a deeper understanding of the teaching qualities of effective lecturers that vocational students desire, students assessment preferences and preferred learning environments. This study gives a voice to higher vocational students as it is important for vocational educators to learn what attracts students to effective learning. Due to the inquiry’s exploratory nature, an interpretivist approach was used, and a constructivist grounded approach using qualit...

  8. The Effects of Treatment upon the Relationship between Vocational Interest and Vocational Ability of the Educable Mentally Retarded Adolescent.

    Science.gov (United States)

    Stodden, Robert A.; Lazar, Alfred L.

    1979-01-01

    Findings suggested that the prevocational exploratory experience was statistically effective in contributing to a positive change in the relationship between Ss' vocational interests and ability. (Author/DLS)

  9. Clean Energy Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    For the past several years, the IEA and others have been calling for a clean energy revolution to achieve global energy security, economic growth and climate change goals. This report analyses for the first time progress in global clean energy technology deployment against the pathways that are needed to achieve these goals. It provides an overview of technology deployment status, key policy developments and public spending on RDD&D of clean energy technologies.

  10. Laws and regularities of vocational pedagogy | Ronzhina | Journal ...

    African Journals Online (AJOL)

    The issue under study is relevant, since a modern pedagogical science needs to establish a dialectical relationship between the theory and practice of vocational education, because research in this area as well as in vocational pedagogy has lagged behind the implemented practical transformations and reforms in recent ...

  11. The Vocational Personality of School Psychologists in the United States

    Science.gov (United States)

    Toomey, Kristine D.; Levinson, Edward M.; Morrison, Takea J.

    2008-01-01

    This study represents the first empirical test of the vocational personality of US school psychologists. Specifically, we investigated the personality of school psychologists using Holland's (1997) well-researched theory of vocational personalities and work environments. The sample consisted of 241 randomly selected members of the National…

  12. The Interdependency of Vocational and Liberal Aims in Higher Education

    Science.gov (United States)

    Abowitz, Kathleen Knight

    2006-01-01

    Many college and university students are zeroed in on their vocational pursuits. Often very narrowly focused, many college students simplistically equate a college education with a vocational education. In situations of advising, teaching, or life coaching, teachers often encounter students who believe that college is largely preparation for a…

  13. Factors Influencing Assessment Quality in Higher Vocational Education

    Science.gov (United States)

    Baartman, Liesbeth; Gulikers, Judith; Dijkstra, Asha

    2013-01-01

    The development of assessments that are fit to assess professional competence in higher vocational education requires a reconsideration of assessment methods, quality criteria and (self)evaluation. This article examines the self-evaluations of nine courses of a large higher vocational education institute. Per course, 4-11 teachers and 3-10…

  14. The vocational education and training system in Denmark

    DEFF Research Database (Denmark)

    Cort, Pia; Wiborg, Susanne

    2009-01-01

    Analysis of developments in vocational education and training systems in Australia, Canada, Denmark, France, Germany, Korea, Mexico, Morocco, the UK and the US.......Analysis of developments in vocational education and training systems in Australia, Canada, Denmark, France, Germany, Korea, Mexico, Morocco, the UK and the US....

  15. Liberal Conservatism, Vocationalism and Further Education in England

    Science.gov (United States)

    Fisher, Roy; Simmons, Robin

    2012-01-01

    Focusing on vocational learning in the English further education (FE) sector and situating it within its social, political and historical context, this paper provides an overview of English attitudes towards the vocational and its subordinate status in relation to "academic" education. It outlines the development of FE in England,…

  16. Gender-Mainstreaming in Technical and Vocational Education and Training

    Science.gov (United States)

    Nurhaeni, I. D. A.; Kurniawan, Y.

    2018-02-01

    Gender differences should be considered in vocational high schools so women and men can develop their potentials without being inhibited by gender bias. Gender mainstreaming in vocational high schools is a strategy to integrate gender differences at all stages in teaching-learning process for achieving gender equality and equity. This research evaluates the implementation of gender mainstreaming in vocational high schools consisting of seven key components of gender mainstreaming. Four vocational high schools in Sragen Regency Indonesia have been purposively selected. The data were obtained through in-depth interviews and documentation studies. The data were analyzed using Kabeer’s model of gender analysis. The findings show that not all key components of gender mainstreaming have been implemented in vocational high schools. Most vocational high schools have implemented three of seven key components of gender mainstreaming, namely political will and leadership, policy framework and gender statistics. Meanwhile four of seven key components of gender mainstreaming, namely structure and mechanism, resources, infra structures and civil society have not been well-implemented. In conclusion gender mainstreaming has not been implemented effectively in vocational high schools. Accordingly, the government’s education office should continue to encourage and publish guidelines on the implementation of gender-mainstreaming in vocational high schools.

  17. The Role of Vocational Education in Agriculture--Economic Efficiency.

    Science.gov (United States)

    McMillion, Martin B.

    1982-01-01

    Vocational agriculture is education for work. By meeting the needs of the economy and the job market, it can meet the needs of the individual. Although human resource development is important, vocational agriculture should focus on job-relevant competencies and cost effectiveness. (SK)

  18. Vocational Interests (The Self-Directed Search) of Female Carpenters

    Science.gov (United States)

    Swan, Kathy C.

    2005-01-01

    In this national sample of female carpenters (N=411) who began their apprenticeship with the United Brotherhood of Carpenters during the 1990s in the United States, the author provides a profile of female carpenters' vocational interests (The Self-Directed Search). The vocational interests of 137 male carpenters also were gathered for comparison.…

  19. Collaborative learning in a culturally diverse secondary vocational education

    NARCIS (Netherlands)

    Dr. Rutger van de Sande; Drs. Kennedy Aquilino Tielman; Dr. S. Bolhuis; Prof. dr. Perry den Brok

    2010-01-01

    Collaborative learning in a culturally diverse secondary vocational education. By K. Tielman (Fontys), P. den Brok (ESoE), S. Bolhuis (Fontys) and R. van de Sande (Fontys) This contribution discusses a descriptive study on the experiences of students and teachers in secondary vocational education

  20. Predictors of Collateral Learning Transfer in Continuing Vocational Training

    Science.gov (United States)

    Hinrichs, Anja-Christina

    2014-01-01

    Against the background of demographic change and skill shortages continuing vocational training is of great significance in Germany. However, the training effectiveness is mostly assessed only at the end of a training program or several months after the training. Since in continuing vocational training the two contexts learning field (training)…

  1. Interdisciplinarity in Vocational Guidance: An Action Theory Perspective

    Science.gov (United States)

    Valach, Ladislav; Young, Richard A.

    2009-01-01

    In addressing the issue of interdisciplinary research in vocational guidance, twelve propositions important for understanding the vocational guidance process as joint, goal-directed action are presented. They address the encounter between client and counsellor leading to relational ethics, the relevance of everyday action theory and methods for…

  2. Vocational Home Economics Education. Coalition Statement. Second Edition.

    Science.gov (United States)

    Home Economics Education Association, Gainesville, VA.

    This pamphlet contains the statement of the Coalition of the American Home Economics Association, American Vocational Association, and Home Economics Education Association regarding the scope and definition of vocational home economics education. It is intended to serve as a basis for professional action. Sections of this statement address the…

  3. Identifying Learning Preferences in Vocational Education and Training Classroom Settings

    Science.gov (United States)

    Smith, Peter J.

    2006-01-01

    This research was designed to assess whether teachers and trainers of vocational learners noted and valued differences in individual learning preferences and, if so, how those differences were observed in natural classroom, workshop or other formal learning settings. Data were collected from six vocational education and training (VET) learning…

  4. Vocational Preferences of Early Adolescents: Their Development in Social Context.

    Science.gov (United States)

    Vondracek, Fred W.; Silbereisen, Rainer K.; Reitzle, Matthias; Wiesner, Margit

    1999-01-01

    This study compared the timing of early vocational preferences in young adolescents from former East Germany and West Germany. Results suggested that as the memory of the Communist system fades and as younger adolescents have had less exposure to it, East-West differences tend to disappear. The formation of early vocational preferences was…

  5. The Vocational Preference Inventory Scores and Environmental Preferences

    Science.gov (United States)

    Kunce, Joseph T.; Kappes, Bruno Maurice

    1976-01-01

    This study investigated the relationship between vocational interest measured by the Vocational Preference Inventory (VPI) and preferences of 175 undergraduates for structured or unstructured environments. Males having clear-cut preferences for structured situations had significantly higher Realistic-Conventional scores than those without…

  6. Measuring Vocational Preferences: Ranking versus Categorical Rating Procedures.

    Science.gov (United States)

    Carifio, James

    1978-01-01

    Describes a study to compare the relative validities of ranking v categorical rating procedures for obtaining student vocational preference data in exploratory program assignment situations. Students indicated their vocational program preferences from career clusters, and the frequency of wrong assignments made by each method was analyzed. (MF)

  7. Cognitive Styles and Educational-Vocational Preferences and Selection

    Science.gov (United States)

    Osipow, Samuel H.

    1969-01-01

    Vocational Preference Inventory (VPI) and other instruments administered to 365 students, both undecided and in various interest fields, revealed several differences in cognitive style. No differences regarding cognitive style variations and VPI high-point codes or ease of vocational selection were observed. (Author/CJ)

  8. A Multi-Dimensional Measure of Vocational Identity Status

    Science.gov (United States)

    Porfeli, Erik J.; Lee, Bora; Vondracek, Fred W.; Weigold, Ingrid K.

    2011-01-01

    Establishing a worker identity is among the most central aspects of the transition from adolescence to adulthood. Despite its importance, few measures with acceptable psychometric and conceptual characteristics exist to assess vocational identity statuses. This study reports the development and evaluation of the Vocational Identity Status…

  9. Towards ESP Programmes in Technical and Vocational Institutions in Malaysia.

    Science.gov (United States)

    Shukor, Haji; And Others

    This paper examines the nature of vocational, technical, and polytechnic education in Malaysia, the extent to which English for special purposes (ESP) programs are incorporated into such education, and the need for ESP program reform. In 1992, Malaysia possessed 70 vocational and 9 technical secondary schools, all of which offered some form of ESP…

  10. Curriculum-Based Vocational Assessment (CBVA) in Florida.

    Science.gov (United States)

    Pfenninger, Peggy; Stodden, Robert

    This guide is designed to assist districts in developing and implementing Curriculum-Based Vocational Assessment (CBVA) as an integral part of the career/vocational program for students with disabilities. The document begins with a User's Guide that describes each part of the guide and makes suggestions for its use. Part 1 explains what CBVA is…

  11. Effective Management of Wastages in Vocational Education for ...

    African Journals Online (AJOL)

    gold

    2012-07-26

    Jul 26, 2012 ... work. The efficient management of vocational education in Nigeria will. Effective .... For instance it is sheer waste of technical skill where an engineer is appointed to head ... vocational education as a source of wastage, since the available skilled .... The need for funding Business Education programmes in.

  12. Is Adult Reading a Guide to Educational-Vocational Achievement?

    Science.gov (United States)

    Athanasou, James A.

    2011-01-01

    Reading is theorised as a key aspect of one's educational and vocational adjustment. The reading scores on the "Wide-Range Achievement Test 3" of 465 adult vocational assessment clients were examined. Reading varied across a range of social factors and the overall results were consistent with earlier studies, especially the "Adult…

  13. Commercial Foods and Culinary Arts. Florida Vocational Program Guide.

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This guide identifies considerations in the organization, operation, and evaluation of secondary and postsecondary vocational education programs. It contains both a vocational program guide and Career Merit Achievement Plan (Career MAP) for commercial foods and culinary arts. The guide contains the following sections: occupational description;…

  14. Student Competency Profile Chart: A Competency Based Vocational Education Instrument.

    Science.gov (United States)

    Martell, John L.

    This document defines, describes usage of, and provides samples of student competency profiles being used in 17 vocational programs at Rutland Area Vocational-Technical Center in Rutland, Vermont. The profiles cover the following programs: auto body, auto mechanics, business/data processing, cabinetmaking, carpentry/masonry, culinary arts,…

  15. Philosophical and Sociological Overview of Vocational Technical Education in Nigeria

    Science.gov (United States)

    Kennedy, Odu Oji

    2012-01-01

    Vocational Technical Education is any kind of education which has the main purpose of preparing one for employment in recognized occupation. The foundation of vocational technical education is based on philosophy which was mainly established for self-employment and self-reliance of the individual(s) who partake in it. Viewing the philosophy and…

  16. Big Questions Facing Vocational Psychology: A Cognitive Information Processing Perspective

    Science.gov (United States)

    Reardon, Robert C.; Lenz, Janet G.; Sampson, James P., Jr.; Peterson, Gary W.

    2011-01-01

    This article draws upon the authors' experience in developing cognitive information processing theory in order to examine three important questions facing vocational psychology and assessment: (a) Where should new knowledge for vocational psychology come from? (b) How do career theories and research find their way into practice? and (c) What is…

  17. Linear Programming for Vocational Education Planning. Interim Report.

    Science.gov (United States)

    Young, Robert C.; And Others

    The purpose of the paper is to define for potential users of vocational education management information systems a quantitative analysis technique and its utilization to facilitate more effective planning of vocational education programs. Defining linear programming (LP) as a management technique used to solve complex resource allocation problems…

  18. Future Directions for Vocational Education in Australian Secondary Schools.

    Science.gov (United States)

    Gonczi, Andrew

    1997-01-01

    Critics of vocational education do not recognize its potential to develop outcomes similar to general education. Vocational curriculum should be based on a holistic integrated model of competence, stressing problem solving and workplace learning, that might serve as the model for general curriculum. (SK)

  19. Vocational Crystallization and Self Esteem in College Students

    Science.gov (United States)

    Resnick, Harvey; And Others

    1970-01-01

    A positive relationship between vocational crystallization and self esteem was assessed by observing differences on two measures of vocational crystallization in students high and low in self esteem scores. No differences according to self esteem were observed. Differences were observed in the certainty of high and low self esteem students. The…

  20. Policy Choices in Vocational Education [and] Technical Appendix.

    Science.gov (United States)

    Institute for the Future, Menlo Park, CA.

    This report examines the impact of changes in the vocational education environment that are likely to be important to policymakers over the next fifteen years. It contains forecasts of a number of trends that will be of significance to vocational educators, an analysis of the policy implications of those trends in the education environments, and…

  1. Integrating Social Class into Vocational Psychology: Theory and Practice Implications

    Science.gov (United States)

    Diemer, Matthew A.; Ali, Saba Rasheed

    2009-01-01

    Although social class plays a salient and significant role in career development and occupational attainment, social class is underrepresented in vocational psychology theory, scholarship, and practice. Vocational psychologists are in a unique position to meet the career development needs of persons from all social classes by integrating a fuller…

  2. Vocational Training in the Textiles and Clothing Industries in Greece.

    Science.gov (United States)

    Drimousis, I.; Zisimopoulos, A.

    This document examines the circumstances under which vocational training in Greece is provided for jobs in the textile and clothing industries. Its objective is to identify guidelines for vocational training for a skilled work force at regional and national levels and to contribute to job mobility between industries. Statistical data,…

  3. Vocational and Technical Education Performance Standards and Competencies.

    Science.gov (United States)

    Connecticut State Board of Education, Hartford.

    These Connecticut vocational and technical performance standards and competencies are a guide for overall quality attainment in these seven vocational and technical program areas: agricultural science technology education; business and finance technology education; cooperative work education; family and consumer sciences education; marketing…

  4. A Critical Study of Vocational-Industrial Education in Taiwan.

    Science.gov (United States)

    Koo, Po-Ken

    This study was concerned with determining the kind of vocational-industrial educational programs that would best suit the needs of Taiwan. The general conditions and provisions of 27 existing vocational-industrial programs were studied to determine their strengths and weaknesses and to provide a set of principles that would serve as guideposts for…

  5. Using the Computer in Special Vocational Programs. Inservice Activities.

    Science.gov (United States)

    Lane, Kenneth; Ward, Raymond

    This inservice manual is intended to assist vocational education teachers in using the techniques of computer-assisted instruction in special vocational education programs. Addressed in the individual units are the following topics: the basic principles of computer-assisted instruction (TRS-80 computers and typing on a computer keyboard); money…

  6. Developing Strategic Leadership for Administrators: Private Vocational College Study

    Science.gov (United States)

    Jumnongya, Areeya; Sirisuthi, Chaiyuth; Chansirisira, Pacharawit

    2015-01-01

    The purpose of this study is to study and define a number of factors measuring quality and efficiency in administrators of private vocational college, and to test and evaluate the efficiency of the strategic leadership program. Twelve factors and 83 indicators were identified as vital for strategic leadership for private vocational college…

  7. Relation of Disability Type and Career Thoughts to Vocational Identity

    Science.gov (United States)

    Yanchak, Kristen V.; Lease, Suzanne H.; Strauser, David R.

    2005-01-01

    This study compared dysfunctional career thoughts and perceptions of vocational identity for individuals with different types of disabilities and examined whether the relation of career thoughts to vocational identity was moderated by type of disability. Ninety adults with cognitive and physical impairments were administered the Career Thoughts…

  8. Vocational Education in the Third World: Revisiting the Debate.

    Science.gov (United States)

    Abrokwa, Clemente K.

    1995-01-01

    Since the 1960s, the goals of vocational education in developing countries have not been achieved. Present economic conditions and lack of public sector jobs are causing students to reevaluate occupational aspirations. Vocational education needs to be redefined to suit the current socioeconomic context and student needs. (SK)

  9. The Work Sample: Reality-Based Assessment of Vocational Potential.

    Science.gov (United States)

    Mobilization for Youth, Inc., New York, NY.

    Developed as a handbook, this document is intended to serve as a technical guide for establishing vocational evaluation units as a means of screening minorities for successful job placement and fulfillment. In the proposed vocational evaluation units, the potential employee uses the tools, materials, and equipment of a given occupation in a…

  10. Vocational Education in Prison--An Alternative to Recidivism.

    Science.gov (United States)

    Luftig, Jeffrey T.

    1978-01-01

    A study of the relationship between participation in institutional vocational education programs in Minnesota correctional institutions and employment status during parole supports the theory that correctional vocational education can help to increase the employability of exoffenders. Data on parolees' employment status and reincarceration are…

  11. Training Needs of Vocational Forestry Staff in Ogun State Nigeria ...

    African Journals Online (AJOL)

    These concerns gave rise to this study with specific objectives to level of knowledge and level of skills of vocational staff in forestry activities. Data were collected using a simple random sampling technique in the selection of 50% of vocational staff totaling 143 respondents. Descriptive statistics and inferential statistics were ...

  12. The Effect of Situated Learning on Students Vocational English Learning

    Science.gov (United States)

    Özüdogru, Melike; Özüdogru, Fatma

    2017-01-01

    The current study aimed to find out the effect of situated learning on students' Vocational English learning. This research employed a mixed method research design. In the quantitative part of the study, pre-tests and post-tests were implemented to investigate the differences in students' vocational English learning between the experimental and…

  13. Youth Unemployment in Nigeria: The Relevance of Vocational and ...

    African Journals Online (AJOL)

    Youth Unemployment in Nigeria: The Relevance of Vocational and Technical Education. ... Vocational/technical education has been an integral part of national development strategies in many societies because of its impact on human resource development, productivity, and economic ... NESG Economic Indicators Vol.

  14. Vocational Pedagogical Competencies of a Professor in the Secondary Vocational Education System: Approbation of Monitoring Model

    Science.gov (United States)

    Andryukhina, Lyudmila M.; Dneprov, Sergey ?.; Sumina, Tatyana G.; Zimina, Elena Yu.; Utkina, Svetlana N.; Mantulenko, Valentina V.

    2016-01-01

    The relevance of the researched issue is preconditioned by the strategic changes in the secondary vocational education system taking place not only in Russia, but also in the majority of industrially developed countries. Provision of the system with qualified pedagogical staff is the leading strategic objective of development of the secondary…

  15. Two Hour Vocational Classes at the Laurel County Area Vocational School. Final Report.

    Science.gov (United States)

    Moore, James E.

    This developmental project with a research component was initiated at the Laurel County Vocational School with the major objective of determining if 2-hour instructional blocks could be operated in programs enrolling only secondary students. Subobjectives involved data gathering and statistical analyses on (1) student achievement, (2) ratings of…

  16. 200 Years of Vocational Education, 1776-1976; The Vocational Education Age Emerges, 1876-1926

    Science.gov (United States)

    Barlow, Melvin L.

    1976-01-01

    The beginnings of vocational education are more readily seen during the period 1876-1926. They are characterized by the rise of manual training, trade schools, home economics movements, and agricultural education. The Smith-Hughes Act was passed in response to the demands of the National Society for the Promotion of Industrial Education. (EC)

  17. European Vocational Education Systems. A Guide to Vocational Education and Training in the European Community.

    Science.gov (United States)

    Collins, Helen

    This book describes the 12 vocational education systems conducted by the members of the European Community. The 12 country chapters (Belgium, Denmark, France, Germany, Greece, Ireland, Italy, Luxembourg, The Netherlands, Portugal, Spain, and the United Kingdom) follow the same model and are organized into the following six sections: key facts,…

  18. Mindfulness, Therapy and Vocational Values: Exploring the Moral and Aesthetic Dimensions of Vocational Education and Training

    Science.gov (United States)

    Hyland, Terry

    2011-01-01

    The devaluation and debilitation of education in general and vocational education and training (VET) in particular has been explored and described in recent years by a wide range of critical commentators. Education stands in dire need of therapy, and this paper suggests a therapeutic process for rejuvenating and enhancing VET through attention to…

  19. Re-Contextualizing Vocational Didactics in Norwegian Vocational Education and Training

    Science.gov (United States)

    Nore, Haege

    2015-01-01

    This article explores teachers and trainers didactical practices in different contexts in Norwegian VET: schools and workplaces. With the introduction of e-resources and e-portfolios in VET, learners as well as teachers and trainers experience a more hybrid learning-arena, which claims for a re-contextualization of vocational didactics as well as…

  20. Communication Skill Attributes Needed for Vocational Education enter The Workplace

    Science.gov (United States)

    Wahyuni, L. M.; Masih, I. K.; Rejeki, I. N. Mei

    2018-01-01

    Communication skills are generic skills which need to be developed for success in the vocational education entering the workforce. This study aimed to discover the attributes of communication skill considered important in entering the workforce as perceived by vocational education students. The research was conducted by survey method using questionnaire as data collecting tool. The research population is final year student of D3 Vocational education Program and D4 Managerial Vocational education in academic year 2016/2017 who have completed field work practice in industry. The sampling technique was proportional random sampling. Data were analyzed with descriptive statistics and independent sampel t-test. Have ten communication skills attributes with the highest important level required to enter the workplace as perceived by the vocational education diploma. These results indicate that there was the same need related communication skills to enter the workforce

  1. Industrial Internship and Entrepreneurship Competencies on Vocational High School Students

    Science.gov (United States)

    Wendi, H. F.; Kusumah, I. H.

    2018-02-01

    The purpose of the research is to explore the influence of internship and vocational skill to student’s entrepreneurship competencies. The research used ex post facto approach. Population in this research is all students of Vocational High School in Bandung, Indonesia. The sample of 40 respondents was determined by proportional random sampling technique. The data were collected by instrument questionnaire and test. Data analysis used descriptive statistics and multiple linear regression. The results show that almost half students have a low the competencies of an entrepreneur. The hypothesis testing shows many the influence of factory teaching has a positive and significant effect on the competencies of an entrepreneur. Similarly, vocational skills have positive influence and significant on the competencies of an entrepreneur. Respectively, the influence of factory teaching and vocational skills expertise collectively have the effect on the competencies of an entrepreneur. Therefore, the influence of factory teaching and vocational skills are effective to student’s entrepreneurship cap competencies.

  2. Vocational behavior analysis in psychology students

    Directory of Open Access Journals (Sweden)

    María Estrella LÓPEZ PÉREZ

    2014-06-01

    Full Text Available Introduction. The European Higher Education Area (EHEA is supporting gain relevance of vocational guidance into the frame of University Education. In order to a better planning of this guidance we need to know his contents evaluating student vocational interests of each center. The aim of the study is to analyze the indicators of Psychology students vocational behavior and his evolution and comparing those results with data of another students population. Methodology. The 329 psychology students participants from the University of Salamanca (248 in the second year and 81 in the fifth answered the questionnaire of university biodata (Rocabert, 2005. In all cases we took a significance level of ? = 0.05 carrying out samples comparison tests using U de Mann-Whitney techniques and contingency analysis. Results: The present study found significant differences between second and fifth psychology grade students and with general university population data collected by Rocabert, Descals and Gomez (2007. In general, psychology students begin their degrees with a high level interest and motivated; they are making decisions based on the academic specialty they want to work in. However, for last year students group (fith year students we detected a lower satisfaction in their studies, more difficulties in deciding what they want to do and a greater demand of information in order to choose the advisablest option for them. Conclusions. Despite the high motivation of psychology students, the nearer is his integration into the job market the higher is the need of guidance to help them to take decisions concerning specialization or the professional world.

  3. Teacher Professionalism in Technical and Vocational Education

    Science.gov (United States)

    Tampang, B. L. L.; Wonggo, D.

    2018-02-01

    The advancement of a nation is largely determined by the advancement of education, and the field of education is on the teachers’ shoulders. Therefore, professionalism of teachers should be improved in performing their duties as facilitators, initiators, and motivators in achieving the competence of graduates. Teachers should be able to facilitate the learning process and pay attention to the development of learners in its various dimensions, leading to the ownership and development of intelligence, learning skills, attitudes, work skills, and social independence. Vocational education carried by Vocational High School, should not only provide theory, but also be coupled with the application or application of theory. It is time for us to rise up to give birth to professional experts in their fields, in accordance with the needs of the workforce. A professional teacher is required to have a work ethic and a high commitment to his profession, and always through continuous development through professional organizations, the internet, books, seminars, and the like. With the professionalism of teachers, then the future teacher does not appear again only as a teacher (teacher), such a prominent function during this, but switch as coach, counselor, and learning manager. Each Educational Institution of Education Personnel graduate and other college graduates who wish to become teachers are required to have at least the competence of the standard. Thus, teacher professionalism is a life-long and never-ending process. Developing and developing vocational education is an important and absolute thing to do, considering that approximately 80% of the workforce in the field is lower middle-level workforce.

  4. CD137 pathway: immunology and diseases

    National Research Council Canada - National Science Library

    Chen, Lieping

    2006-01-01

    ... may work in either interconnected or linear fashion. Therefore, the combined understanding of each pathway, their interactions with other pathways, and the functional consequence, is a cornerstone for our interpretation of pathological basis of diseases and future treatments. It is important to stay abreast on the pace of progress, which I refer to as periodic summary of incremental and breakthrough discoveries in each pathway by the experts and the leader in the field. The CD137 Pathway: Immu...

  5. World Wide Comparism of Technical and Vocational Education: Lessons for Nigerian Technical and Vocational Education Sector (I)

    Science.gov (United States)

    Ayeni, Abiodun Olumide

    2015-01-01

    This paper compared technical/vocational education in: Germany, Australia, Finland, Hong Kong, Hungary, India, Japan, South Korea, Mexico, and Nigeria, and found that technical/vocational education was given proper attention in countries considered except Nigeria, where it was handled with laissez faire attitude. Set-Up of Technical/Vocational…

  6. Factorial Validity of the Vocational Interest Scales of the Holland Vocational Preference Inventory for Australian High School Students.

    Science.gov (United States)

    Athanasou, James A.; And Others

    1981-01-01

    The structure of the six vocational interests measured by the Holland Vocational Preference Inventory was identified. Results of two separate analyses showed that a general factor accounted for much of the total variance. Remaining bipolar factors supported previous classifications of interests. (Author/GK)

  7. Curriculum-Based Vocational Assessment Handbook: A Guide to the Implementation of Curriculum-Based Vocational Assessment Activities. Revised.

    Science.gov (United States)

    Stodden, Robert A.; Ianacone, Robert N.

    This handbook is for persons, especially teachers, who collect, evaluate, and apply vocational assessment information for handicapped students in the Department of Defense Dependents Schools (DoDDS). The approach used is a developmental curriculum-based assessment process which responds to the career/vocational programming sequence through the…

  8. Paradoxes in Danish Vocational Education and Training

    DEFF Research Database (Denmark)

    Louw, Arnt Vestergaard; Katznelson, Noemi

    2015-01-01

    All vocational education and training schools in Denmark are required to launch retention initiatives and report yearly on their efforts to increase retention and the completion rate of their students. This article argues that the structural conditions and incentive structure around VET produces...... teaching practices in VET that create unmotivated, weak students and unintentional push-out effects. Further, it is suggested that the marketization of education has a profound effect on the practice in VET such that good education has come to be more associated with retaining all students in the VET...

  9. Progress Report

    DEFF Research Database (Denmark)

    Duer, Karsten

    1999-01-01

    Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999.......Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999....

  10. Progress Report

    Science.gov (United States)

    2018-05-16

    This report summarizes the annual progress of EPA’s Clean Air Markets Programs such as the Acid Rain Program (ARP) and the Cross-State Air Pollution Rule (CSAPR). EPA systematically collects data on emissions, compliance, and environmental effects, these data are highlighted in our Progress Reports.

  11. 38 CFR 21.130 - Educational and vocational courses outside the United States.

    Science.gov (United States)

    2010-07-01

    ... vocational courses outside a State if the case manager determines that such training is in the best interest... vocational courses outside the United States. 21.130 Section 21.130 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation...

  12. [Chronically ill and unemployed? A review on vocational status in multiple sclerosis].

    Science.gov (United States)

    Kern, S; Kühn, M; Ziemssen, T

    2013-02-01

    Multiple sclerosis (MS) is one of the most common neurological disorders in young adults. It is characterised by a chronic progressive course with far reaching implications on the patient's private and professional life. Based on the current literature, employment status is analysed in relation to disease-specific, therapeutic, psychosocial, and socioeconomic factors. A special emphasis is placed on the vocational status of MS patients in Germany. According national and international studies, around 40 % of all MS patients are currently unemployed. Main reasons for early retirement are disease-specific factors such as impaired mobility, disability in the upper extremities, fatigue, and cognitive impairment. According to the German Multiple Sclerosis Registry (GMSR), these symptoms are still insufficiently treated. In patients with minor motoric impairment (EDSS ≤ 3.0), depressive symptoms seem to have a major impact on employment status. Disease progression, older age at diagnosis, and hard physical work are negative predictors in terms of employment situation. The lack of flexible working hours, the inability to have flexible resting times at work, a lack of understanding from colleagues and employers as well as the personal attitude were main non-disease-specific reasons for early retirement. The current knowledge on the vocational status in MS is mainly based on international studies (e. g., Scandinavia, England, USA, Australia, MSIF Survey). For Germany, only the GMSR supports significant information on the employment status of MS patients. According to the GMSR, ataxia, fatigue and cognitive dysfunction are still insufficiently treated - a situation that is at least partly due to insufficient treatment options. Comprehensive studies that focus on a broad range of possible influencing factors on vocational status of German MS patients are currently lacking. © Georg Thieme Verlag KG Stuttgart · New York.

  13. Internet Literacy of Vocational High School Teachers

    Science.gov (United States)

    Vernanda, D.; Abdullah, A. G.; Rohendi, D.

    2018-02-01

    Internet literacy is needed to know the development of the world in various things quickly and precisely, as well as in the world of education, especially teachers. Seeing the importance of internet literacy, there is an interest to discuss and analyze the level of internet literacy of teachers. The method used in this research is descriptive qualitative. The sample of research is vocational school teacher (SMK) as many as 99 respondents. Data are collected through questionnaires. The theory used is adopted from Suitable Learning Object Type (LRE APV4.7) and Three Elements of Literacy Digital. The result data of the questionnaire is processed and analyzed using Capability Maturity Model theory, the result of the research shows that the level of internet literacy of vocational teachers is at level 2, meaning that SMK teachers have used the internet many times to assist their daily activities and have pattern of repetition in internet utilization. The use of internet by teachers of SMK with various needs that support the process of teaching, communicating, sharing knowledge, but the most dominant is to communicate through social media. Factors affecting internet usage include age, gender, and employment status.

  14. Pathway Interaction Network Analysis Identifies Dysregulated Pathways in Human Monocytes Infected by Listeria monocytogenes

    Directory of Open Access Journals (Sweden)

    Wufeng Fan

    2017-01-01

    Full Text Available In our study, we aimed to extract dysregulated pathways in human monocytes infected by Listeria monocytogenes (LM based on pathway interaction network (PIN which presented the functional dependency between pathways. After genes were aligned to the pathways, principal component analysis (PCA was used to calculate the pathway activity for each pathway, followed by detecting seed pathway. A PIN was constructed based on gene expression profile, protein-protein interactions (PPIs, and cellular pathways. Identifying dysregulated pathways from the PIN was performed relying on seed pathway and classification accuracy. To evaluate whether the PIN method was feasible or not, we compared the introduced method with standard network centrality measures. The pathway of RNA polymerase II pretranscription events was selected as the seed pathway. Taking this seed pathway as start, one pathway set (9 dysregulated pathways with AUC score of 1.00 was identified. Among the 5 hub pathways obtained using standard network centrality measures, 4 pathways were the common ones between the two methods. RNA polymerase II transcription and DNA replication owned a higher number of pathway genes and DEGs. These dysregulated pathways work together to influence the progression of LM infection, and they will be available as biomarkers to diagnose LM infection.

  15. Biobehavioral Influences on Cancer Progression

    Science.gov (United States)

    Costanzo, Erin S.; Sood, Anil K.; Lutgendorf, Susan K.

    2010-01-01

    Synopsis This review focuses on the contributions of stress-related behavioral factors to cancer growth and metastasis and the biobehavioral mechanisms underlying these relationships. We describe behavioral factors that are important in modulation of the stress response and the pivotal role of neuroendocrine regulation in the downstream alteration of physiological pathways relevant to cancer control, including the cellular immune response, inflammation, and tumor angiogenesis, invasion, and cell-signaling pathways. Consequences for cancer progression and metastasis, as well as quality of life, are delineated. Finally, behavioral and pharmacological interventions for cancer patients with the potential to alter these biobehavioral pathways are discussed. PMID:21094927

  16. Progressive Business

    DEFF Research Database (Denmark)

    Christiansen, Christian O.

    2016-01-01

    Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015.......Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015....

  17. Methodology for vocational psychodiagnostics of senior schoolchildren using information technologies

    Science.gov (United States)

    Bogdanovskaya, I. M.; Kosheleva, A. N.; Kiselev, P. B.; Davydova, Yu. A.

    2017-01-01

    The article identifies the role and main problems of vocational psychodiagnostics in modern socio-cultural conditions. It analyzes the potentials of information technologies in vocational psychodiagnostics of senior schoolchildren. The article describes the theoretical and methodological grounds, content and diagnostic potentials of the computerized method in vocational psychodiagnostics. The computerized method includes three blocks of sub-tests to identify intellectual potential, personal qualities, professional interests and values, career orientations, as well as subtests to analyze the specific life experience of senior schoolchildren. The results of diagnostics allow developing an integrated psychodiagnostic conclusion with recommendations. The article contains options of software architecture for the given method.

  18. Pathways to Employment and Quality of Life for Apprenticeship and Traineeship Graduates with Disabilities

    Science.gov (United States)

    Cocks, Errol; Thoresen, Stian H.; Lee, Elinda Ai Lim

    2015-01-01

    People with disabilities have low participation rates in employment and vocational education and training. Thirty adults with disabilities were sampled from an Australian longitudinal study of economic and social outcomes achieved by graduate apprentices and trainees. Participants were surveyed and interviewed to identify pathways from high school…

  19. Reforming Vocational Didactics by Implementing a New VET Teacher Education in Denmark: Tensions and Challenges Reflected in Interviews with Vocational College Teachers

    Science.gov (United States)

    Duch, Henriette; Andreasen, Karen E.

    2015-01-01

    A new education program, Diploma of Vocational Pedagogy, has recently been implemented in Denmark to upskill vocational college teachers and improve didactics at VET colleges in general. Among many challenges, vocational college teachers have to adapt their pedagogy to a large number of students from backgrounds with no tradition for education.…

  20. Career Management Skills Among Vocational Students

    Science.gov (United States)

    Zakaria, Normah; Yamin, Azlin; Maarof, Rosmawati

    2017-08-01

    Career management skills are important elements that should be present in each individual, because career selection process is crucial for school leavers. The phenomenon of students who are less knowledgeable about career at the end of school is among the main reasons they choose a career that does not fit. The situation is very worrying and poses various negative implications such as work stress and frequent swapping of jobs. In fact, research has found that most vocational students have a low level of career management. Therefore, this study is aimed to identify career management skills that students possess. The research design was a survey using a quantitative approach with a number of samples, n = 480. Data was analysed using statistical software, Statistical Package for the Social Sciences (SPSS). The results show that students’ overall career management skills are moderate. To develop human capital with the right competence, career management skills are critical requirements that can fill the gaps in industry.

  1. Secondary Vocational Education in Working Environment

    Directory of Open Access Journals (Sweden)

    Gvido Melink

    2001-12-01

    Full Text Available The authors present a successful project of secondary vocational education carried out by our school for the occupation of a toolmaker and a machinist for the companies Domel, Indramat and Niko in Železniki, considering the modern methods of teaching adults and having consistently adjusted timetable of the lectures in accordance with the working hours of the candidates and the production process respectively. Lectures, training and practical work in the workshop were performed in the company and school's workshops and laboratories. In the additional chapter the authors draw attention to the problems of payment for the teachers of technical s ubjects, who enter the education process with great working experience from companies but start here as beginners since the school regulations do not define such cases.

  2. ADVANCED LEVEL VOCATIONAL TRAINING STUDENTS’ SELF ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Zsuzsanna KISS

    2017-06-01

    Full Text Available This paper is intended to clarify the phenomenon that lower achieving students tend to evaluate their own academic performance less accurately than those who do better in their studies. Previous studies have found that lower performers generally overestimate while higher performers underestimate their performance. The current study analyses self-assessment behaviour and efficiency among Hungarian higher vocational education students. We found that the lowest level of higher education students typically overestimate their performance. Our results strengthen the empirical evidences from previous studies that showed that higher-achieving students evaluate their performance more accurately than their lower achieving fellows. Furthermore we found that higher-achieving students tend to over-assess their examination results to a lesser degree than low-achieving students. We also analysed the difference between the two genders. Compared to female students, males tend to overestimate their own performance.

  3. VOCATIONAL EDUCATION, WORK AND KNOWLEDGE PRODUCTION

    Directory of Open Access Journals (Sweden)

    Naira Lisboa Franzoi

    2015-12-01

    Full Text Available The paper presents the case study about a reasearch developed in a vocational education school, by two students. They are workers from a region of tobacco industry in the interior of Rio Grande do Sul/Brazil. The focus is on how the dialogue between the school knowledge, and the students’ experiencial knowledge took place. It is a theoretical essay of seeing an use of Three Poles Dynamic Device - methodological tool proposed by Ergology. The concepts of human activity, work, knowledge and Three Poles Dynamic Device (DD3P are the theoretical framework of the study. Our objetctiv is to give visibility to a successful experience in a public school whose audience are young and adult workers , and exploring the possibilities of using a theoretical and methodological tool that aims to promote dialogue between academic knowledge and knowledge engaged in work activity. Thus, we believe we are contributing to the teaching practice and the theoretical - methodological field , still under construction.

  4. Aquatic pathway 2

    International Nuclear Information System (INIS)

    1977-01-01

    This third part of the investigation discusses the preliminary results of sub-investigations concerning problems of the release of radioactive substances into the environment via the water pathway. On the basis of papers on the emission into the draining ditch and the exchange processes there, investigations of a possible incorporation via different exposure pathways are reported. Special regard is paid to drinking water supply aquatic foodstuffs, the river sediment, the utilisation of the agricultural surfaces and the draining ditch including its pre-pollution. The dynamics of contamination processes is reported on with regard to the problem of accidents. The colloquium will give an outline of the progress made so far and admit participants' suggestions for further work on the sub-investigations. The following colloquia will report further findings, in particular effects on aquatic ecosystems. (orig.) [de

  5. Towards distributed leadership in vocational education and training schools

    NARCIS (Netherlands)

    Bouwmans, M.H.C.F.; Runhaar, P.R.; Wesselink, R.; Mulder, M.

    2017-01-01

    Complex educational innovations in vocational education and training (VET) schools require teamwork and distributed leadership so that team members are enabled to contribute based on their expertise. The literature suggests that distributed leadership is affected by formal leaders’ and teachers’

  6. Training Needs of Vocational Forestry Staff in Ogun State Nigeria.

    African Journals Online (AJOL)

    Onyii Ogbonna

    Vocational staff perceived their knowledge level and skill level as medium ... Many state forest reserves in the country were originally set up in recognition of the .... officers are not expected to know anything in marketing of timber( = 3.225) .

  7. Change Vocational Funding to Acquire Qualified Math/Science Teachers.

    Science.gov (United States)

    Heron, Bill

    1985-01-01

    Gives a brief overview of the problems occurring at the high school level due to inadequately paid personnel in the math and science areas, summarizes the current bureaucratic structure surrounding vocational funding, and suggests an alternative. (FL)

  8. The Peripheralisation of the Danish Vocational Education System

    DEFF Research Database (Denmark)

    Larsen, Karin Topsø

    2013-01-01

    in the supply of vocationally trained labour. This is especially problematic for labour markets in non-metropolitan areas, where a number of production- and service- firms are still located. At the same time more and more youth are choosing and completing academic education programs, which target work places......In the past decade, the Vocational Education Training System (VET) in Denmark has undergone a downturn in which fewer and fewer students apply for and complete a vocational education. Choosing a vocational education has become synonymous with choosing the losing team. The result is a drastic drop...... in metropolitan areas and support a migration flow of young educated people from rural municipalities toward metropolitan areas....

  9. Vocational Identity and Ego Identity Status in Korean Nursing Students

    Directory of Open Access Journals (Sweden)

    Hyun-Young Koo, PhD, RN

    2016-03-01

    Conclusions: These findings show that nursing students in identity achievement status have secure and clear vocational identities. Further longitudinal and qualitative studies are needed to find out if identity formation among nursing students changes with age.

  10. Working for a living: the vocational decision making of lesbians.

    Science.gov (United States)

    Hook, Misty K; Bowman, Sharon

    2008-01-01

    While lesbians are similar to other women in that they face discrimination in the workplace based on gender, ethnicity and class, they also have unique needs and confront bias because of their sexual orientation. Thus, choosing an occupation is an extremely important task for many lesbians. In order to adequately serve a lesbian population, vocational counselors need to be aware of how lesbians choose occupations. Astin's (1985) and Gottfredson's (1981) theories of career development can be adapted to help explain the vocational needs of lesbians. This article will review the major findings within the field, discuss how the two theories relate to the vocational decision-making process of lesbian women and make suggestions for how to do vocational counseling with lesbians.

  11. gender and career choice differences on bakare vocational interest

    African Journals Online (AJOL)

    enduring personality characteristics that describe or determine an individual .... literature on vocational counseling outside the post primary school settings in Nigeria. ... Such inter correlations according to Bakare (1977) testify to the construct.

  12. Students’ Preferred Characteristics of Learning Environments in Vocational Secondary Education

    Directory of Open Access Journals (Sweden)

    Ingeborg Placklé

    2014-12-01

    Full Text Available If teachers and teacher educators are willing to support the learning of students, it is important for them to learn what motivates students to engage in learning. Students have their own preferences on design characteristics of powerful learning environments in vocational education. We developed an instrument - the Inventory Powerful Learning Environments in Vocational Education - to measure students’ preferences on characteristics of powerful learning environments in vocational education. We investigated whether student preferences on the design of their learning environments are in line with what is described in the literature as beneficial for learning. Data of 544 students show that the preferences of students support most characteristics of PLEs in vocational education. Looking through the eyes of students, teachers have to challenge their students and encourage them to take their learning in their own hands. Adaptive learning support is needed. Remarkable, students do not prefer having reflective dialogues with teachers or peers.

  13. Vocational Education with a Twist: This School Teaches Community Service.

    Science.gov (United States)

    Lewis, Barbara

    1983-01-01

    At Davis Vocational Technical High School in Lincoln (Rhode Island) students in such areas as carpentry, culinary arts, and cosmetology provide free services to the community and gain valuable experience. (Author/JM)

  14. The Implications of Theory Z for Departments of Vocational Education.

    Science.gov (United States)

    Dillon, Linda S.

    1983-01-01

    Describes the Theory Z management approach as postulated by William G. Ouchi and presents steps to be considered by postsecondary departments of vocational education attempting to implement this approach. (NRJ)

  15. Effects of Welfare Reform on Vocational Education and Training

    Science.gov (United States)

    Dave, Dhaval M.; Reichman, Nancy E.; Corman, Hope; Das, Dhiman

    2011-01-01

    Exploiting variation in welfare reform across states and over time and using relevant comparison groups, this study estimates the effects of welfare reform on an important source of human capital acquisition among women at risk for relying on welfare: vocational education and training. The results suggest that welfare reform reduced enrollment in full-time vocational education and had no significant effects on part-time vocational education or participation in other types of work-related courses, though there appears to be considerable heterogeneity across states with respect to the strictness of educational policy and the strength of work incentives under welfare reform. In addition, we find evidence of heterogeneous effects by prior educational attainment. We find no evidence that the previously-observed negative effects of welfare reform on formal education (including college enrollment), which we replicated in this study, have been offset by increases in vocational education and training. PMID:22125356

  16. Teacher Expectancy Related to Student Performance in Vocational Education.

    Science.gov (United States)

    Curtis, Samuel M.; Pandya, Himanshu S.

    1980-01-01

    This experiment explored the effect of teacher expectations on vocational students' cognitive and psychomotor skills and on attitudes. Although teachers' expectations changed student attitudes toward teachers and subjects, neither expectations nor attitude change had an effect on student achievement. (SK)

  17. Barriers to participation in vocational orientation programmes among prisoners

    Directory of Open Access Journals (Sweden)

    Dorien Brosens

    2015-11-01

    Full Text Available This study investigates the barriers to prisoners’ participation in vocational education, as well as the predictors of different types of barriers. Survey data derived from a project in a remand prison in Belgium (N=468 provided the empirical evidence for the analyses. The results indicate that facing situational and informational barriers are most common. Based on the different kinds of barriers, various types of non-participants can be distinguished and multinomial logistic regression analyses are conducted to identify in what way participants of vocational education differ from various types of non-participants. For instance, prisoners with a poor understanding of the Dutch language and those who never/rarely receive visitors participate less in vocational education as they are more likely to be confronted with informational barriers. We conclude this article by discussing paths for future research and implications for policy and practice to anticipate the barriers for those who want to participate in vocational education.

  18. Moral development and citizenship education in vocational schools

    NARCIS (Netherlands)

    Leenders, H.; Veugelers, W.; de Kat, E.

    2012-01-01

    We investigate the objectives, practical application, and learning outcomes of moral education and citizenship education at three vocational schools in the Netherlands (VMBO). We explore teachers’ and students’ pedagogical, sociopolitical, and moral development objectives and how they deal with

  19. Employment experiences of vocationally trained doctors.

    Science.gov (United States)

    Osler, K

    1991-09-28

    To investigate the expectations and employment experiences of male and female doctors who completed vocational training in East Anglia during 1981-7 and to examine the factors which had influenced those who had changed direction early in their careers. Survey conducted by confidential postal questionnaire. Britain. 281 doctors, 233 (83%) of whom responded. Ideal choice of work on completion of vocational training; present employment; factors which had restricted present choice of work; factors associated with reported satisfaction with job. 77/83 (93%) men and 130/150 (87%) women had hoped to work in general practice (p = 0.75). A smaller proportion of women (71%; 106) than men (89%; 74) were in general practice posts (p less than 0.01); only 6% (nine) of women were on maternity leave or caring for children without paid employment. More women than men were working in medical jobs other than general practice (18% (27) women v 4% (three) men; p less than 0.01). 44/91 (49%) women with children had achieved their employment goals compared with 47/59 (80%) women without children and 55/71 (78%) men with children. 87% (72/83) of men and 65% (98/150) of women had achieved the status of principal (p less than 0.01). 162/193 (84%) doctors who had worked in general practice reported satisfaction with their jobs. Dissatisfaction was linked with doing a job different from that hoped for and with perceiving that the share of practice income did not accurately reflect their share of the practice workload. Steps need to be taken to retain women in general practice, including a statutory part time pay allowance and incentives for practices to allow flexible working hours for doctors with young children.

  20. Progressive posterior cortical dysfunction

    Directory of Open Access Journals (Sweden)

    Fábio Henrique de Gobbi Porto

    Full Text Available Abstract Progressive posterior cortical dysfunction (PPCD is an insidious syndrome characterized by prominent disorders of higher visual processing. It affects both dorsal (occipito-parietal and ventral (occipito-temporal pathways, disturbing visuospatial processing and visual recognition, respectively. We report a case of a 67-year-old woman presenting with progressive impairment of visual functions. Neurologic examination showed agraphia, alexia, hemispatial neglect (left side visual extinction, complete Balint's syndrome and visual agnosia. Magnetic resonance imaging showed circumscribed atrophy involving the bilateral parieto-occipital regions, slightly more predominant to the right . Our aim was to describe a case of this syndrome, to present a video showing the main abnormalities, and to discuss this unusual presentation of dementia. We believe this article can contribute by improving the recognition of PPCD.

  1. Progressive posterior cortical dysfunction

    Science.gov (United States)

    Porto, Fábio Henrique de Gobbi; Machado, Gislaine Cristina Lopes; Morillo, Lilian Schafirovits; Brucki, Sonia Maria Dozzi

    2010-01-01

    Progressive posterior cortical dysfunction (PPCD) is an insidious syndrome characterized by prominent disorders of higher visual processing. It affects both dorsal (occipito-parietal) and ventral (occipito-temporal) pathways, disturbing visuospatial processing and visual recognition, respectively. We report a case of a 67-year-old woman presenting with progressive impairment of visual functions. Neurologic examination showed agraphia, alexia, hemispatial neglect (left side visual extinction), complete Balint’s syndrome and visual agnosia. Magnetic resonance imaging showed circumscribed atrophy involving the bilateral parieto-occipital regions, slightly more predominant to the right. Our aim was to describe a case of this syndrome, to present a video showing the main abnormalities, and to discuss this unusual presentation of dementia. We believe this article can contribute by improving the recognition of PPCD. PMID:29213665

  2. Vocational identity of deaf and hard of hearing adolescents

    Directory of Open Access Journals (Sweden)

    Šešum Mia

    2016-01-01

    Full Text Available Vocational identity development represents the key aspect of identity development and it is one of the most significant issues in the period of adolescence. The persons with strong vocational identity have clearer understanding of their own career goals and they are characterized by greater self-confidence and dedication to their career choices, which is the reason why they decide on their future profession more quickly and more easily than the persons whose vocational identity is weaker. The career development of deaf and hard of hearing adolescents takes place under conditions of auditory deprivation, which may have a negative effect on the stability of their vocational identity and thus on their choice of profession, employment and assimilation into the working environment. This study examines the connection between vocational identity of deaf and hard of hearing adolescents and the number of completed school years and age, as well as the effect of gender, the level of hearing impairment, primary mode of communication, and general performance at school at the end of a school term on vocational identity. The sample comprised 97 deaf and hard of hearing students attending seventh and eighth grades of primary school as well as all grades of secondary school, who are educated in segregating conditions in the territory of Serbia. 'My Vocational Situation' (MVS, Holland et al., 1980-a was used as the instrument. The results of the study, following the data analysis, point to the connection between vocational identity of deaf and hard of hearing adolescents and the number of school years completed and age, as well as the effect of gender on vocational identity, while the effect of the level of hearing impairment, primary mode of communication, and general performance at school on vocational identity of the examinees has not been confirmed. Comparing these results with the results of studies conducted on the population of typically developing

  3. Safety Valve or Sinkhole? Vocational Schooling in South Africa

    OpenAIRE

    Pugatch, Todd

    2012-01-01

    As an alternative to traditional academic schooling, vocational schooling in South Africa may serve as a safety valve for students encountering difficulty in the transition from school to work. Yet if ineffective, vocational schooling could also be a sinkhole, offering little chance for success on the labor market. After defining the terms "safety valve" and "sinkhole" in a model of human capital investment with multiple schooling types, I test for evidence of these characteristics using a pa...

  4. Student performance and satisfaction in continuous learning pathways in Dutch VET

    OpenAIRE

    Biemans, H.J.A.

    2012-01-01

    An important trend in the Vocational Education and Training (VET) system in the Netherlands is the design of continuous learning pathways enclosing more than one school type level. These continuous learning pathways are characterized by different design formats. In this study, the relations between these design formats and student performance and satisfaction were examined. Five coordinators and 161 students of five so-called Green Lycea (GL) in the life sciences domain, in which the elements...

  5. Vocational Literacy in Mozambique: Historical Development, Current Challenges and Contradictions

    Directory of Open Access Journals (Sweden)

    Oleg Popov

    2016-03-01

    Full Text Available The study analyses the historical development of vocational literacy in basic education and Non-Formal Vocational Education (NFVE in Mozambique, as well as current challenges and contradictions. The theoretical lens of Cultural-Historical Activity Theory (CHAT is employed in the study. Methodologically the study was executed through an analysis of oral, printed and e-resources produced by the main stakeholders and also the reflective experiences of the authors in their extensive educational work in the country. The findings reveal poorly developed vocational literacy education in schools and non-formal settings in spite of recurrent political declarations about its importance. There is a strong dependence by formal and particularly NFVE sectors on the technical and financial support provided by international organisations. Vocational literacy courses are characterized by a lack of adequate equipment and poor practice. As a consequence, theoretical or elementary forms of vocational knowledge are dominant in the courses, resulting in the dissatisfaction of both learners and educators. Vocational literacy development proved to be a complex field that faces many challenges and ischaracterised by diverse internal contradictions.

  6. Teacher performance and work environment in the instructional process in vocational school

    Science.gov (United States)

    Kuncoro, Tri; Dardiri, Ahmad

    2017-09-01

    Teachers should have pedagogical, personality, social, and professional competency. stated that performance appraisal has several benefits, namely for the implementation of reward and punishment system, provision of feedback for teachers to develop their competencies, identification of training needs, and diagnosis of problems. According to performance is one's work result or success rate as a whole over a certain period of time in performing tasks compared to various possibilities, such as work standards, targets or criteria which have been predetermined and agreed. One's performance is based on daily tasks and responsibilities assigned to him/her. The racial differences in personality are largely due to different environmental influences, where people of different races have progressed for generations. Vocational high school teachers have a low pedagogic and professional performance. The factors that influence performance, according to the partner-lawyer model proposed, are expectations about rewards, encouragements, abilities, needs and traits, perceptions of tasks, internal and external rewards, perceptions of reward levels and job satisfaction. This study used a survey method to collect data or information about a large population using relatively small samples. The population of this research was vocational high school teachers. Data analysis techniques used the Regression Analysis with the assistance of SPSS. The results of teacher performance are as follows: 1) the pedagogic performance was relatively good; 2) professional performance was relatively good, and the overall performance of vocational high school teachers was still less effective and efficient; 3) the teachers' work environment was 42.5234%; and 4) there was no correlation between work environment and teacher performance, meaning that the work environment (conditions of physical work environment, psychological work environment, and non-physical work environment) does not positively support the

  7. Attitudes of Oregon Vocational Agriculture Teachers Toward the Supervised Occupational Experience Program Component of the Vocational Agriculture Curriculum.

    Science.gov (United States)

    Herren, Ray; Cole, Lee

    1984-01-01

    The main purpose of the study was to determine the attitudes of Oregon vocational agriculture teachers toward supervised occupational experience programs in light of the present economic climate. (JOW)

  8. Pathway cross-talk network analysis identifies critical pathways in neonatal sepsis.

    Science.gov (United States)

    Meng, Yu-Xiu; Liu, Quan-Hong; Chen, Deng-Hong; Meng, Ying

    2017-06-01

    Despite advances in neonatal care, sepsis remains a major cause of morbidity and mortality in neonates worldwide. Pathway cross-talk analysis might contribute to the inference of the driving forces in bacterial sepsis and facilitate a better understanding of underlying pathogenesis of neonatal sepsis. This study aimed to explore the critical pathways associated with the progression of neonatal sepsis by the pathway cross-talk analysis. By integrating neonatal transcriptome data with known pathway data and protein-protein interaction data, we systematically uncovered the disease pathway cross-talks and constructed a disease pathway cross-talk network for neonatal sepsis. Then, attract method was employed to explore the dysregulated pathways associated with neonatal sepsis. To determine the critical pathways in neonatal sepsis, rank product (RP) algorithm, centrality analysis and impact factor (IF) were introduced sequentially, which synthetically considered the differential expression of genes and pathways, pathways cross-talks and pathway parameters in the network. The dysregulated pathways with the highest IF values as well as RPpathways in neonatal sepsis. By integrating three kinds of data, only 6919 common genes were included to perform the pathway cross-talk analysis. By statistic analysis, a total of 1249 significant pathway cross-talks were selected to construct the pathway cross-talk network. Moreover, 47 dys-regulated pathways were identified via attract method, 20 pathways were identified under RPpathways with the highest IF were also screened from the pathway cross-talk network. Among them, we selected 8 common pathways, i.e. critical pathways. In this study, we systematically tracked 8 critical pathways involved in neonatal sepsis by integrating attract method and pathway cross-talk network. These pathways might be responsible for the host response in infection, and of great value for advancing diagnosis and therapy of neonatal sepsis. Copyright © 2017

  9. Molecular Pathways

    Science.gov (United States)

    Lok, Benjamin H.; Powell, Simon N.

    2012-01-01

    The Rad52 protein was largely ignored in humans and other mammals when the mouse knockout revealed a largely “no-effect” phenotype. However, using synthetic lethal approaches to investigate context dependent function, new studies have shown that Rad52 plays a key survival role in cells lacking the function of the BRCA1-BRCA2 pathway of homologous recombination. Biochemical studies also showed significant differences between yeast and human Rad52, in which yeast Rad52 can promote strand invasion of RPA-coated single-stranded DNA in the presence of Rad51, but human Rad52 cannot. This results in the paradox of how is human Rad52 providing Rad51 function: presumably there is something missing in the biochemical assays that exists in-vivo, but the nature of this missing factor is currently unknown. Recent studies have suggested that Rad52 provides back-up Rad51 function for all members of the BRCA1-BRCA2 pathway, suggesting that Rad52 may be a target for therapy in BRCA pathway deficient cancers. Screening for ways to inhibit Rad52 would potentially provide a complementary strategy for targeting BRCA-deficient cancers in addition to PARP inhibitors. PMID:23071261

  10. Restrictions and Countermeasures of Rural Vocational Education in Urban-rural Integration

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Developing rural vocational education is of great significance to urban-rural integration: developing rural vocational education is helpful to cultivating new farmers for construction of new socialist countryside,favorable to improving farmers’ ability of finding jobs and starting undertaking, and beneficial to transfer of rural surplus labor and acceleration of urbanization. Restrictions on development rural vocational education mainly include: low value cognition of society and social assessment of rural vocational education; out of balance of cost and expected return of rural vocational education; the quality of supply of rural vocational education failure to satisfy demand of socio-economic development; imperfect rural vocational education system. In view of these,following countermeasures and suggestions are put forward: strengthen propaganda and guidance to build environment of public opinion for rural vocational education; push forward rural vocational compulsory education system to lay social foundation for rural vocational education; reinforce policy support to assist in building rural vocational education system; improve education system to build overall framework of rural vocational education; perfect laws and regulations to establish system and norm for development of rural vocational education.

  11. Contextualising vocational knowledge : A theoretical framework and illustrations from culinary education

    NARCIS (Netherlands)

    Wenja Heusdens; Arthur Bakker; Dr. Liesbeth Baartman; Prof.Dr. Elly de Bruijn

    2016-01-01

    In this article the idea of contextualising vocational knowledge is theorised to understand the nature of vocational knowledge and this process of contextualising is illustrated with empirical examples from culinary education.

  12. Extended Teams in vocational education: Slow starters but worth the wait

    NARCIS (Netherlands)

    Mazereeuw, Marco; McKenney, Susan; Wopereis, Iwan

    2015-01-01

    This study was undertaken due to the notorious frustrations of vocational educators and workplace supervisors concerning (mis)alignment between school and work contexts. Extended teams, consisting of vocational teachers and workplace supervisors, were established to share responsibility for the

  13. 77 FR 48973 - Notice of Proposed Information Collection Requests; Office of Vocational and Adult Education...

    Science.gov (United States)

    2012-08-15

    ... deadline dates for submission of performance and financial reports for the Office of Vocational Adult... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Office of Vocational and Adult Education; Perkins Discretionary Grant Performance Report SUMMARY: The Perkins Discretionary...

  14. General educational disciplines practice-oriented training in intermediate vocational education

    Directory of Open Access Journals (Sweden)

    Liya G. Skorobogatova

    2011-01-01

    Full Text Available The article concerns crucial issues of practice-oriented training in Russia's intermediate vocational education, designates directions of general educational disciplines study in intermediate vocational education.

  15. Non-Smad signaling pathways.

    Science.gov (United States)

    Mu, Yabing; Gudey, Shyam Kumar; Landström, Maréne

    2012-01-01

    Transforming growth factor-beta (TGFβ) is a key regulator of cell fate during embryogenesis and has also emerged as a potent driver of the epithelial-mesenchymal transition during tumor progression. TGFβ signals are transduced by transmembrane type I and type II serine/threonine kinase receptors (TβRI and TβRII, respectively). The activated TβR complex phosphorylates Smad2 and Smad3, converting them into transcriptional regulators that complex with Smad4. TGFβ also uses non-Smad signaling pathways such as the p38 and Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) pathways to convey its signals. Ubiquitin ligase tumor necrosis factor (TNF)-receptor-associated factor 6 (TRAF6) and TGFβ-associated kinase 1 (TAK1) have recently been shown to be crucial for the activation of the p38 and JNK MAPK pathways. Other TGFβ-induced non-Smad signaling pathways include the phosphoinositide 3-kinase-Akt-mTOR pathway, the small GTPases Rho, Rac, and Cdc42, and the Ras-Erk-MAPK pathway. Signals induced by TGFβ are tightly regulated and specified by post-translational modifications of the signaling components, since they dictate the subcellular localization, activity, and duration of the signal. In this review, we discuss recent findings in the field of TGFβ-induced responses by non-Smad signaling pathways.

  16. EMERALD - Vocational training in medical radiation physics

    International Nuclear Information System (INIS)

    Lewis, C.A.; Tabakov, S.D.; Roberts, V.C.

    2000-01-01

    EMERALD (European MEdiation RAdiation Learning Development) is a project funded by the European Union under the Leonardo da Vinci programme. It involves a collaboration between Universities and Hospitals from the UK, Sweden, Italy and Portugal. The aim of the EMERALD project is to develop and deliver three common transnational vocational training modules in Medical Radiation Physics in the specific areas of Diagnostic Radiology, Nuclear Medicine and Radiotherapy. These modules are intended to be used in the training programme for young professionals involved in medical radiation physics. Each module is developed from a series of competencies. The competencies are acquired by undertaking practical tasks described in a workbook given to each trainee. Once the task has been completed the trainee discusses the results and observations with his supervisor to ensure that the appropriate competency has been achieved. In addition to the workbook, each trainee receives a CD-ROM containing a series of images to help describe each task. The workbooks for each subject area have been completed and students from Sweden have undertaken Diagnostic Radiology training in the United Kingdom using this approach. The project is now entering the next phase; to develop a multimedia version of the workbook. (author)

  17. Vocational Teaching-Learning through the Eyes of Undergraduate Vocational Students in Malta: A Qualitative Exploratory Study

    Directory of Open Access Journals (Sweden)

    Alison Said

    2018-04-01

    Full Text Available The purpose of this study is to develop a deeper understanding of the teaching qualities of effective lecturers that vocational students desire, students assessment preferences and preferred learning environments. This study gives a voice to higher vocational students as it is important for vocational educators to learn what attracts students to effective learning. Due to the inquiry’s exploratory nature, an interpretivist approach was used, and a constructivist grounded approach using qualitative data was adopted. A purposive approach to multiple case study selection was used where the unit of analysis was a higher vocational student. The perceptions and expectations of vocational undergraduate (EQF level 6 students in two disciplines (applied science and engineering were explored, to identify what may constitute good practice. A total of ten participants from two different institutes within the vocational university college agreed to be interviewed. Semi-structured and photo-elicitation interviews were applied. In addition, the Powerful Learning Environments (PLEs Framework was used as a preliminary tool to aid in the decision-making process for data collection. Iterative analysis was used for the semi- structured interviews, whilst a constant-comparative method was used for the photo- elicitation image analysis. Overall, the expectations and preferences between both groups were very similar. Results show that students expect to be taught by interactive lectures that relate theory to practice that will prepare them for the job. Formal lectures including presentations were the least favoured. Regarding teaching qualities, students expect approachable and understanding lecturers who provide concrete industrial examples. Assessment preferences included home based assignments and research projects. The preferred learning environment is in line with most characteristics of the Powerful Learning Environment. Evidence shows that there is no

  18. Measuring progress

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2007-01-01

    In recent years, sociological examinations of genetics, therapeutic cloning, neuroscience and tissue engineering have suggested that 'life itself' is currently being transformed through technique with profound implications for the ways in which we understand and govern ourselves and others...... in much the same way that mortality rates, life expectancy or morbidity rates can. By analysing the concrete ways in which human progress has been globally measured and taxonomised in the past two centuries or so, I will show how global stratifications of countries according to their states...

  19. Quality Education in English class in vocational college

    Institute of Scientific and Technical Information of China (English)

    童燕黎

    2010-01-01

    Quality education in English teaching in elementary education should transit from examination-oriented education to quality education,which is an explicit requirement of CPC Central Committee and the State Council to the education in vocational colleges.Quality education in vocational colleges faces the challenges of the 21st century education and needs to be carried out in-depth reform.This paper collects different kinds of books and information about the Quality education.It tries to answer the following questions:what is the quality education in vocational college? What contents does it include? In the past years,many English teachers and educators have made a great effort in this area,and they have got great achievements in this field.Therefore,to strengthen the quality education in vocational college is the core and the key to the students.The reform and opening up to the world,the rapid economic development and the rapid expansion of foreign exchanges of China today demands the quality education in vocational college as particularly importance in English Teaching.

  20. Progressivity Enhanced

    Directory of Open Access Journals (Sweden)

    Marko Hren

    2013-09-01

    Full Text Available Rather than a scientific text, the author contributes a concise memorandum from the originator of the idea who has managed the campaign for the conversion of the military barracks into a creative cluster between 1988 and 2002, when he parted ways with Metelkova due to conflicting views on the center’s future. His views shed light on a distant period of time from a perspective of a participant–observer. The information is abundantly supported by primary sources, also available online. However, some of the presented hypotheses are heavily influenced by his personal experiences of xenophobia, elitism, and predatorial behavior, which were already then discernible on the so-called alternative scene as well – so much so that they obstructed the implementation of progressive programs. The author claims that, in spite of the substantially different reality today, the myths and prejudices concerning Metelkova must be done away with in order to enhance its progressive nature. Above all, the paper calls for an objective view on internal antagonisms, mainly originating in deep class divisions between the users. These make a clear distinction between truly marginal ndividuals and the overambitious beau-bourgeois, as the author labels the large part of users of Metelkova of »his« time. On these grounds, he argues for a robust approach to ban all forms of xenophobia and self-ghettoization.

  1. Welding. COM-LINK. Competency Based Vocational Curricula with Basic Skills and Academic Linkages.

    Science.gov (United States)

    Browning, Terry

    This competency-based module uses the Ocean County (New Jersey) Vocational-Technical Schools curriculum-infused model for infusing basic skills instruction into vocational education. The model demonstrates the relationship of vocational skills to communication, mathematics, and science. The document begins with a philosophy statement; preface; a…

  2. Contextualising Vocational Knowledge: A Theoretical Framework and Illustrations from Culinary Education

    Science.gov (United States)

    Heusdens, W. T.; Bakker, A.; Baartman, L. K. J.; De Bruijn, E.

    2016-01-01

    The nature of knowledge in vocational education is often described in dichotomies such as theory versus practice or general versus specific. Although different scholars now acknowledge that vocational knowledge is more than putting bits of theoretical and practical knowledge together, it is still unclear how vocational knowledge should be…

  3. The Relationship between Transformational Leadership and Organizational Commitment: The Case for Vocational Teachers in Jordan

    Science.gov (United States)

    Khasawneh, Samer; Omari, Aieman; Abu-Tineh, Abdullah M.

    2012-01-01

    The purpose of this article is to determine the relationship between transformational leadership of vocational school principals on vocational teachers-organizational commitment. A random sample of 340 vocational teachers responded to a three-part instrument (the transformational leadership questionnaire, the organizational commitment…

  4. Designing innovative learning environments to foster communities of learners for students in initial vocational education

    NARCIS (Netherlands)

    Boersma, A.; ten Dam, G.T.M.; Wardekker, W.L.; Volman, M.L.L.

    2016-01-01

    In this study, the concept of ‘community of learners’ was used to improve initial vocational education. The framework of a ‘community of learners for vocational orientation’ that we present offers both a theoretical understanding of teaching–learning processes in initial vocational education and

  5. Designing innovative learning environments to foster communities of learners for students in initial vocational education

    NARCIS (Netherlands)

    Boersma, A.; ten Dam, G.; Wardekker, W.; Volman, M.

    In this study, the concept of ‘community of learners’ was used to improve initial vocational education. The framework of a ‘community of learners for vocational orientation’ that we present offers both a theoretical understanding of teaching–learning processes in initial vocational education and

  6. The Financing of Vocational Education and Training in France. Financing Portrait. CEDEFOP Panorama.

    Science.gov (United States)

    Michelet, Valerie

    This report examines the financing of the two components of France's vocational education and training (VET) system. They are initial vocational training (IVT), which includes upper secondary and short forms of higher education, and continuing vocational training (CVT), which aims to help workers adapt to changes in working techniques and…

  7. The Effect of Profile Elevation on the Relationship between Interest Differentiation and Vocational Identity

    Science.gov (United States)

    Im, Seongah

    2011-01-01

    This study examines the varying relationships between vocational identity and differentiation of vocational interests while taking into account levels of profile elevation as the moderator. The participants were 130 high school students who attended a vocational guidance programme at a youth counselling centre in Korea. The relationship between…

  8. 38 CFR 21.4232 - Specialized vocational training-38 U.S.C. Chapter 35.

    Science.gov (United States)

    2010-07-01

    ... Vocational Rehabilation Panel, determine whether such a course is in the best interest of the eligible person... interest. (3) Both the counseling psychologist and the Vocational Rehabilitation Panel will assist in... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Specialized vocational...

  9. Relation of Vocational Identity Statuses to Interest Structure among Swiss Adolescents

    Science.gov (United States)

    Hirschi, Andreas

    2011-01-01

    Vocational identity is one core component of identity construction in adolescence. The current study investigated whether vocational interest structure in terms of differentiation, coherence, elevation, and interest-aspiration congruence would differentiate among students in vocational identity achievement, foreclosure, moratorium, and diffusion.…

  10. Exploration on the Evaluation Mode of "International Trade Practice" in Higher Vocational Schools

    Science.gov (United States)

    Li, Yamin

    2011-01-01

    Considering the employment-oriented positioning of higher vocational education which is put by the education ministry and the features of higher vocational schools students, this paper indicates that the disadvantages in the evaluation mode of higher vocational school international trade course. Therefore, a reformed suggestion is given for the…

  11. Entrepreneur Program. COM-LINK. Competency Based Vocational Curricula with Basic Skills and Academic Linkages.

    Science.gov (United States)

    De Maria, Richard

    This competency-based module uses the Ocean County (New Jersey) Vocational-Technical Schools curriculum-infused model for infusing basic skills instruction into vocational education. The document consists of matrices that describe the relationship of vocational skills to basic communication, mathematics, and science skills within the entrepreneur…

  12. Intrasubject Predictions of Vocational Preference: Convergent Validation via the Decision Theoretic Paradigm.

    Science.gov (United States)

    Monahan, Carlyn J.; Muchinsky, Paul M.

    1985-01-01

    The degree of convergent validity among four methods of identifying vocational preferences is assessed via the decision theoretic paradigm. Vocational preferences identified by Holland's Vocational Preference Inventory (VPI), a rating procedure, and ranking were compared with preferences identified from a policy-capturing model developed from an…

  13. Supporting Vocationally Oriented Learning in the High School Years: Rationale, Tasks, Challenges

    Science.gov (United States)

    Halpern, Robert

    2012-01-01

    This article highlights the limitations of our current educational system in terms of vocational learning and highlights the role that vocational learning can play in supporting youth development and improving youth outcomes. It discusses the role that nonschool settings can play in supporting vocational learning and suggests strategies to improve…

  14. Caring Disposition and Subordination. Swedish Health and Social Care Teachers' Conceptions of Important Vocational Knowledge

    Science.gov (United States)

    Rehn, Helena; Eliasson, Eva

    2015-01-01

    Based on the increasing demands for vocational training in upper secondary school to adapt to workplace conditions, the aim of this article is to explore vocational teachers' conceptions regarding vocational knowledge. Drawing on a social constructionist perspective, this study analysed data from 17 interviews. The study showed how power dynamics,…

  15. Vocational Assessment for Special Needs Individuals. Project Final Report, Phase I, 1979-1980.

    Science.gov (United States)

    Stodden, Robert A.

    The present state of the art of vocational evaluation is largely manifested within the field of vocational rehabilitation, and as a result, the concepts, instrumentation, and strategies do not lend themselves readily to an educational setting. This project attempted to bridge the gap between the conceptualized model of vocational evaluation within…

  16. Vocational Assessment of Special Needs Individuals Project: Final Report. Phase II.

    Science.gov (United States)

    Stodden, Robert A.

    The Vocational Assessment of Special Needs Individuals Project originated with the regional vocational schools and educational collaboratives of the Assabet and Blackstone Valleys cooperating to determine a meaningful process through which vocational assessment information could be collected, organized, and used in formulating a basis for…

  17. 38 CFR 21.53 - Reasonable feasibility of achieving a vocational goal.

    Science.gov (United States)

    2010-07-01

    ... achieving a vocational goal. 21.53 Section 21.53 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... achieving a vocational goal. (a) Requirement. The Department of Veterans Affairs shall determine the reasonable feasibility of achieving a vocational goal in each case in which a veteran has either: (1) An...

  18. How Has Vocational Culinary Arts Changed as a Result of a Redesign of the Education System.

    Science.gov (United States)

    VanLandingham, Paul G.

    Vocational education reforms that followed passage of the Carl D. Perkins Vocational Education Act of 1963 initiated the development of many new vocational culinary arts programs that trained high school students with state-of-the art equipment. When the National Consortium of Competency Based Education was established in 1973, it changed the form…

  19. 38 CFR 21.6001 - Temporary vocational training program for certain pension recipients.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Temporary vocational training program for certain pension recipients. 21.6001 Section 21.6001 Pensions, Bonuses, and Veterans... Program of Vocational Training for Certain New Pension Recipients General § 21.6001 Temporary vocational...

  20. Reflections on Developing Secondary Vocational Education in High-Poverty Areas

    Science.gov (United States)

    Liu, Jiang; Chen, Guofeng

    2013-01-01

    Developing vocational education is a necessity for the economic and social development of high-poverty areas in China. But vocational education in impoverished areas lacks social recognition and faces funding shortages, along with difficulties in recruiting students. Vocational high schools themselves also have shortcomings. This article considers…

  1. Fashion Merchandising. COM-LINK. Competency Based Vocational Curricula with Basic Skills and Academic Linkages.

    Science.gov (United States)

    Williams, Edwina

    This competency-based module uses the Ocean County (New Jersey) Vocational-Technical Schools curriculum-infused model for infusing basic skills instruction into vocational education. The model demonstrates the relationship of vocational skills to communication, mathematics, and science. The document begins with a philosophy statement; preface; a…

  2. Examination of Job Satisfaction of the Medical Vocational High School Teachers

    Science.gov (United States)

    Bayraktar, Hatice Vatansever; Güney, Burcu

    2016-01-01

    The aim of this study is to determine the job satisfaction level of Medical Vocational High School teachers and whether it differs according to different variables. The research was organized in accordance with the screening model. The population of the research was composed of vocational course teachers who worked in Medical Vocational High…

  3. The Role of Vocational Education in Economic Development in Malaysia: Educators' and Employers' Perspectives.

    Science.gov (United States)

    Mustapha, Ramlee B.; Greenan, James P.

    2002-01-01

    Responses from 276 of 300 vocational educators and 53 of 120 employers in Malaysia indicated that both groups believed vocational education contributes to economic development and vocational graduates had good technical skills but needed better employability skills. They wanted more government collaboration with the private sector. (Contains 26…

  4. Curriculum Development and Adaptation in Vocational Education in Taiwan, Republic of China.

    Science.gov (United States)

    Chang, Tien-Jin Frank

    Taiwan has recently changed from an agricultural to an industry-intensive society. Vocational education should assume the responsibility of educating students to meet the manpower needs of industry, and vocational education programs have rapidly expanded. The government lists technical and vocational education as one of the top priorities in the…

  5. 20 CFR 220.134 - Medical-vocational guidelines in appendix 2 of this part.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Medical-vocational guidelines in appendix 2... THE RAILROAD RETIREMENT ACT DETERMINING DISABILITY Vocational Considerations § 220.134 Medical-vocational guidelines in appendix 2 of this part. (a) The Dictionary of Occupational Titles includes...

  6. Modularisation Approaches in Initial Vocational Education: Evidence for Policy Convergence in Europe?

    Science.gov (United States)

    Pilz, Matthias; Li, Junmin; Canning, Roy; Minty, Sarah

    2018-01-01

    One response to challenges of national vocational training systems has been a move towards greater flexibility within vocational training systems. This article focuses on an investigation of modularisation as a tool for achieving this flexibility. Many European countries have introduced modular forms into their vocational training system. We…

  7. 34 CFR 403.1 - What is the State Vocational and Applied Technology Education Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the State Vocational and Applied Technology... TECHNOLOGY EDUCATION PROGRAM General § 403.1 What is the State Vocational and Applied Technology Education Program? (a) Under the State Vocational and Applied Technology Education Program, the Secretary makes...

  8. Task Listings Resulting from the Vocational Competency Measures Project. Memorandum Report.

    Science.gov (United States)

    American Institutes for Research in the Behavioral Sciences, Palo Alto, CA.

    This memorandum report consists of 14 task listings resulting from the Vocational Competency Measures Project. (The Vocational Competency Measures Project was a test development project that involved the writing and verification of task listings for 14 vocational occupational areas through over 225 interviews conducted in 27 states.) Provided in…

  9. Vocational rehabilitation of young adults with a disability of one arm or hand

    NARCIS (Netherlands)

    Nijboer, I.D.; Wevers, C.J.

    1993-01-01

    The paper presents a summary of a study of the vocational rehabilitation of young adults with a disability of one hand or arm. It demonstrates the importance of labor research in vocational rehabilitation. The success of vocational rehabilitation depends in large measure on the suitability of the

  10. The Role of Vocational Education and Training in Palestine in Addressing Inequality and Promoting Human Development

    Directory of Open Access Journals (Sweden)

    Randa Hilal

    2016-10-01

    Full Text Available UNESCO's new emphasis on vocational education and training as transformative, and concerns in particular with equity and sustainable human development, has been strongly influenced by a recent literature on VET and human development that has a particular focus on the most marginalised, especially young women, and is concerned with how their aspirations, agency and achievement of wellbeing can be promoted in the face of wide-ranging structural obstacles. This article seeks to further develop that account through an even stronger emphasis on VET in the context of extreme poverty, inequality and marginalisation as faced in Palestine. VET in Palestine serves many of the poorest and most disenfranchised in Palestinian society in a context of profound structural obstacles to wellbeing achievement. Our analysis show a very positive story of how VET has helped highly disadvantaged young Palestinians, particularly young women, to make progress on their human development.

  11. Factors of progress in reading literacy test

    Directory of Open Access Journals (Sweden)

    Jovanović Vitomir

    2011-01-01

    Full Text Available The main goal of this study was to identify the factors which are most associated with the progress in reading literacy assessed in the PISA survey. In the preliminary sample, students from ten schools (N=235 were retested two years after the 2009 PISA original study. There were measured intrinsic and extrinsic motivation, school self-efficacy, epistemological beliefs, metacognitive strategies, socio-economic status, enjoyment and preference for reading and motivation and self-regulation. The examined factors explain 27% of the variance in reading literacy progress. Factors that contribute most to this progress are school self-efficacy, proper use of metacognitive strategies and low extrinsic motivation. Socio-economic status explained a negligible amount of variance, while some effect of type of school on progress in reading literacy (η2=7% was observed. Achievement in reading literacy is correlated with school marks. Students who attend secondary schools are more likely to make progress in reading literacy than those who attend vocational schools. An attempt was made to formulate the implications for education policy based on this research.

  12. Vocational training in contemporary Spain: Policies, Agents and Institutions

    Directory of Open Access Journals (Sweden)

    Paulí DÁVILA BALSERA

    2015-04-01

    Full Text Available The vocational training in Spain has reached a late formalization in the educational system. This situation is explained by the economical contexts thatevolve from the agricultural sector to the industrial development of certain zones, which are those who have a better network of vocational schools. In this article three levels of analysis are addressed: the first one, related to the politics and educational legislation, in order to notice the process of formalization; the second one, focused on the relevance of the Church on this sector and, the third one is the role played by the Union Organization during the Franco's regime. In this way, the intervention of the different agents who have contributed to the development of the vocational training in Spain remains clear up to the General Law of Education of 1970.

  13. Determination of Self-Development in the Vocational Educational Environment

    Directory of Open Access Journals (Sweden)

    E. F. Zeer

    2012-01-01

    Full Text Available The paper explores the concept of vocational educational environment combining vocational training, professional development and professional world. The research is aimed at the self-determination analysis of an individual in the above environment. The authors observe the two existing trends of self-development analysis, corresponding with the subjective activity and culturally historical approaches. The empirical research results involve the students’ subjective individual characteristics and factors influencing the self-development strategy selection. The research findings prove the earlier hypothesis of the self- development phenomenon being determined by the two mutually conditioned factors: personal self-control ability and interrelation of the above mentioned components of the vocational educational environment. The authors make the conclusion that the self-development prospects are determined by the internal and external motivation, professional mobility and striving for success. The determination specificity of professional self- development, identified by the authors, can provide the psychological basis for future specialists training. 

  14. On the Incidence of Employment Subsidies to Vocational Training

    DEFF Research Database (Denmark)

    Albæk, Karsten

    The present paper analyses employment subsidies to vocational training under union wage bargaining. The analysis includes an investigation of the consequences of financing the subsidy by a levy on employment, which is the typical way of financing these types of subsidies in many countries. The pa....... The paper demonstrates high incidence rates of subsidies to vocational training under standard assumptions about the preference structure of the union. The financing scheme appears to counteract the purpose of the subsidy.......The present paper analyses employment subsidies to vocational training under union wage bargaining. The analysis includes an investigation of the consequences of financing the subsidy by a levy on employment, which is the typical way of financing these types of subsidies in many countries...

  15. The Incidence of Employment Subsidies for Vocational Training

    DEFF Research Database (Denmark)

    Albæk, Karsten

    2013-01-01

    This paper analyses employment subsidies for vocational training under union wage bargaining. The analysis includes an investigation of the consequences of financing the subsidy by a levy on employment, which is the typical way of financing these types of subsidies in many countries. The paper de...... demonstrates high incidence rates of subsidies for vocational training under standard assumptions about the preference structure of the union. The financing scheme appears to counteract the purpose of the subsidy.......This paper analyses employment subsidies for vocational training under union wage bargaining. The analysis includes an investigation of the consequences of financing the subsidy by a levy on employment, which is the typical way of financing these types of subsidies in many countries. The paper...

  16. Students’ Experiences of Ability-based Streaming in Vocational Education

    DEFF Research Database (Denmark)

    Tanggaard, Lene; Nielsen, Klaus; Helms Jørgensen, Christian

    2015-01-01

    Since 2007, it has been mandatory for all vocational schools in Denmark to assess the prior qualifications of all students when they begin at the school and to use this assessment to divide students into different ability-based courses (streaming) with the aim of increasing the retention of stude......Since 2007, it has been mandatory for all vocational schools in Denmark to assess the prior qualifications of all students when they begin at the school and to use this assessment to divide students into different ability-based courses (streaming) with the aim of increasing the retention...... of students. The purpose of this paper is to explore students’ experiences of being placed on a low-ability course by using case studies of two classes from separate vocational schools in Denmark with different practices regarding the streaming of students....

  17. Critical Success Factor for Implementing Vocational Blended Learning

    Science.gov (United States)

    Dewi, K. C.; Ciptayani, P. I.; Surjono, H. D.; Priyanto

    2018-01-01

    Blended learning provides many benefits to the flexibility of time, place and situation constraints. The research’s objectives was describing the factors that determine the successful implementation of blended learning in vocational higher education. The research used a qualitative approach, data collected through observations and interviews by questionnare based on the CSFs indicators refers to TAM and Kliger. Data analysis was inductive method. The result provided an illustration that the success of vocational blended learning implementation was largely determined by the selection of instructional models that are inline with learning achievement target. The effectiveness of blended learning required the existence of policy support, readiness of IT infrastructure. Changing lecturer’s culture by utilizing ICT can also encourage the accelerated process of successful implementation. It can concluded that determinant factor of successful implementation of blended learning in vocational education is determined by teacher’s ability in mastering the pedagogical knowledge of designing instructional models.

  18. Education for work: Reflections towards a theory of vocational education

    Science.gov (United States)

    Corson, David J.

    1985-12-01

    By integrating aspects of a philosophy of work and a sociology of work, this article draws conclusions relevant to framing a theory of vocational education. `Education for work' is accepted in this paper as the common central meaning of the term `vocational education'. The two concepts, `education' and `work', are first examined separately: `work' is seen to include recreational and occupational work, while occupational work is seen to fall on a continuum ranging from constrained to unconstrained occupational work. `Education' and `training' are distinguished. After a discussion of the conceptual links which might be drawn between `education' and `work', recommendations are made about the aims, the place, and the curriculum of vocational education within the general institution of education.

  19. Progress report

    International Nuclear Information System (INIS)

    Brumovsky, M.

    1979-01-01

    Progress Report, covering the period up to the end of 1979 year, was sent to the IAEA according to the research agreement No. 1971 /CF. This work covered the following fields: preparation and dummy irradiation experiments with a new experimental capsule of ''CHOUCA-M'' type; measurement of temperature fields and design of specimen holders; measurement of neutron energy spectrum in the irradiation place in our experimental reactor of VVR-S type (Nuclear Research Institute) using a set of activation detectors; unification and calibration of the measurement of neutron fluence with the use of Fe, Cu, Mn-Mg and Co-Al monitors; development and improvement of the measuring apparatus and technique for the dynamic testing of pre-cracked specimens with determination of dynamic parameters of fracture mechanics; preparation and manufacture of testing specimens from the Japanese steels - forging, plate and weld metal; preparation of the irradiation capsule for assembling

  20. Community College Pathways: 2013-2014 Descriptive Report

    Science.gov (United States)

    Sowers, Nicole; Yamada, Hiroyuki

    2015-01-01

    The Community College Pathways initiative consists of two pathways, Statway® and Quantway®, that accelerate post-secondary students' progress through their developmental mathematics sequence and a college-level course for credit. Launched in 2011, the Pathways have been remarkably successful, helping thousands of students achieve success in…

  1. SOFT SKILLS COMPETENCE DEVELOPMENT OF VOCATIONAL TEACHER CANDIDATES

    Directory of Open Access Journals (Sweden)

    I Made Sudana

    2015-02-01

    Full Text Available Vocational education curriculum 2013 that applied nationally in the academic year 2014/2015 mandated that religious subject added character educational in which contactwith aspects of soft skills. This needs to be addressed by LPTK as producer vocational teacher candidate, so that future graduates are able to fulfill the mandate of the curriculum. Curriculum vocational teacher candidates who applied seems also still focused on providing hard skills competencies, so that graduates do not have adequate soft skills competence. On the other hand in the world of work has been going on trend shift in terms of hard skills to soft skills.Research and development is designed to go through stages and multiyear to produce soft skills development strategy for prospective teachers of vocational school. Development strategy departs from theoretical studies and mapping needs soft skills aspects of relevant research, analysis and LPTK vocational curriculum, soft skills needs and job requirements of future trends, soft skills required by vocational teachers, teaching soft skills already there, done to map the needs and later for further development until the hypothetical model generated Late models. Subjects were LPTK lecturers, teachers of vocational productive industrials. Data were obtained by observation and interviews, review of documents that the results were analyzed with descriptive qualitative and quantitative techniques. There are several aspects of the soft skills required candidates vocational school teachers, among others: (1 self-discipline, (2 responsibility, (3 the spirit of the work, (4 problem solving, (5 collaboration, (6 the ability of communication, (7 personality, (8 social attitudes, (9 critical thinking, (10 creative thinking and innovative, (11 confidence and (12 self-motivation. Soft skills development strategy skills prospective teachers through extra-curricular with gradual pattern through four stages, namely: (1 the development of

  2. [Relevance of Personality Factors for Successful Vocational Rehabilitation].

    Science.gov (United States)

    Arling, V; Slavchova, V; Knispel, J; Spijkers, W

    2016-02-01

    The Main purpose of vocational rehabilitation is occupational reintegration of clients into the job market who have lost their job or whose job is threatened because of a handicap or chronicl illness. With regard to existing evidence for the relevance of personality factors for work performance and job achievement, the present study investigated the influence of participants' personality factors on a successful reintegration after a retraining program in a vocational training center over 2 years. A central research objective was to identify prognostic personality factors for successful vocational integration. In this longitudinal study 15 vocational training centers participated at 3 time points of measurement (T1, T2 and T3). Data gathering was based on rehabilitants' self-reports (standardized questionnaires: SVF, BSW, SPR, CSES) about personality aspects. First data collection started at the beginning (T1) and a second survey was conducted at the end of the training 2 years later (T2). Based on the data at measurement points T1 and T2, 4 prognostic models were computed (binary logistic regression analysis) and evaluated, examining the differenzial influence of several scales and items on direct reintegration after completing the vocational retraining and reintegration status 6 months later (T3). As expected, different variables turned out to be relevant for occupational integration at the end of the training program and 6 months later. Correspondingly other variables appeared to be relevant for occupational reintegration at T1 and at T2. At the end of the vocational training program, approximately 24% of the participants had a job. With respect to direct reintegration, regression analysis revealed that vocational self-efficacy (R(2)=0,175) and self-evaluation were relevant (R(2)=0,383). Approximately 70% of the participants had gotten a job 6 months later. Several stress coping strategies (R(2)=0,170), estimation of the own reintegration prognosis and aspects

  3. Vocational students' learning preferences: the interpretability of ipsative data.

    Science.gov (United States)

    Smith, P J

    2000-02-01

    A number of researchers have argued that ipsative data are not suitable for statistical procedures designed for normative data. Others have argued that the interpretability of such analyses of ipsative data are little affected where the number of variables and the sample size are sufficiently large. The research reported here represents a factor analysis of the scores on the Canfield Learning Styles Inventory for 1,252 students in vocational education. The results of the factor analysis of these ipsative data were examined in a context of existing theory and research on vocational students and lend support to the argument that the factor analysis of ipsative data can provide sensibly interpretable results.

  4. Long-run Employment Effects of Vocational Rehabilitation

    DEFF Research Database (Denmark)

    Høgelund, Jan; Holm, Anders

    Previous studies find that vocational rehabilitation in terms of education has no or even a negative effect on long-term sick-listed employees’ probability of returning to work. This paper extends previous analyses by assessing the employment effect, using both a return-to-work measure and a meas......Previous studies find that vocational rehabilitation in terms of education has no or even a negative effect on long-term sick-listed employees’ probability of returning to work. This paper extends previous analyses by assessing the employment effect, using both a return-to-work measure...

  5. Preventing Poor Vocational Functioning in Psychosis Through Early Intervention

    DEFF Research Database (Denmark)

    Hegelstad, Wenche Ten Velden; Bronnick, Kolbjorn S; Barder, Helene Eidsmo

    2017-01-01

    OBJECTIVE: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development. METHODS: Generalized estimating equations and mediation analysis were conducted to examine the association between...... employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis. RESULTS: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative...

  6. RELATED VOCATIONAL INTEREST TO LEARNING AND ENTREPRENEURIAL LEARNING ACHIEVEMENT WITH ENTREPRENEURSHIP INTEREST ON THE STUDENS AUTOMOTIVE ENGINEERING ISLAMIC VOCATIONAL SCHOOL YOGYAKARTA ACADEMIC YEAR 2013/2014

    OpenAIRE

    Choiruddin Nurcholis Suwondo; Subagyo Subagyo

    2014-01-01

    The purpose of the study (1) to determine whether there is a positive relationship between vocational interest to learning with entrepreneurship interest on the studens Automotive Engineering Islamic Vocational School Yogyakarta Academic Year 2013/2014; (2) to determine whether there is a positive relationship between entrepreneurial learning achivement with entrepreneurship interest on the studens Automotive Engineering Islamic Vocational School Yogyakarta Academic Year 2013/2014; (3) to det...

  7. Progress report 1997

    International Nuclear Information System (INIS)

    1998-01-01

    The vocation of O.P.R.I. is to prevent the risks coming from ionizing radiations and to develop the means necessary to limit their effects. This protection concerns the workers and the population. Its action covers the monitoring of environment, the registering, centralizing and exploiting of dosimetric surveillance of workers. (N.C.)

  8. VOCATIONAL MASTERS TRANING IN THE CONTEXT OF GROWING SOCIAL AND PROFESSIONAL MOBILITY

    Directory of Open Access Journals (Sweden)

    Alexandr G. Kislov

    2014-01-01

    Full Text Available The study is aimed at investigating the trends of vocational training development reflecting the demands of changing professional world.Methods: The applied methods include historic, genetic and socio-context analysis of the current developments in vocational training sphere.Results: The research findings prove the priority of meta-professional and meta-competency landmarks in vocational masters training.Scientific novelty: The author points out the lagging behind of the Federal State Educational Standard and corresponding vocational training programs compared to the fast growing social and professional mobility. The paper emphasizes the urgent need for vocational pedagogical education as a part of vocational training at all levels - the secondary, higher and postgraduate.Practical significance: The research outcomes can be used for further development of conceptual, methodological, organizational and contextual bases of vocational masters training.

  9. The measures for training professional skills of accounting major in secondary vocational school

    Institute of Scientific and Technical Information of China (English)

    DAJENAH MANNAA QAIDABDO

    2017-01-01

    With the development of economy, the importance of accounting is becoming more and more prominent, and the requirements of relevant industries for accountting have been gradually raised. so more and more people learn accounting, but the the effect of practical teaching in college is not ideal. Taking secondary vocational school as an example, although the accounting is one of the major with long history since secondary vocational colleges started to run, but due to various factors, accounting teaching in secondary vocational colleges is not up to the requirement of the society. Moreover, the teaching quality and teaching efficiency are relatively low, so the status of secondary vocational school is also low in the whole education circle. In order to improve the quality of cultivating professional skills for accounting in secondary vocational schools, and promote the development of accounting teaching in secondary vocational schools, this paper analyzes the current professional skills training for accounting in secondary vocational colleges.

  10. The influence of professional teachers on Padang vocational school students' achievement

    Directory of Open Access Journals (Sweden)

    Ramli Bakar

    2018-01-01

    Full Text Available This study determined: (1 the competency of professional teachers teaching in the classroom, (2 students' achievement in vocational schools in Padang, and (3 the influence of professional teachers on vocational school students' achievement in Padang. The population was 2,647 students in vocational schools. The sample, consisting of 160 students, was selected using a multistage, random sampling technique. Data were collected using questionnaires and documentation, and then analyzed and presented using the SPSS software. The results showed: (1 overall, the professional teachers of vocational schools in Padang had good qualifications in pedagogical competence, professional competence, social competence, and personal competence, (2 the learning process of vocational schools in Padang was going well and in general, student achievement was at a good level of performance, and (3 there was a significant influence of professional teachers on vocational school students' achievement in Padang. Keywords: professional teacher, student achievement, vocational school

  11. Use of international data sets to evaluate and validate pathway assessment models applicable to exposure and dose reconstruction at DOE facilities. Monthly progress reports and final report, October--December 1994

    International Nuclear Information System (INIS)

    Hoffman, F.O.

    1995-01-01

    The objective of Task 7.lD was to (1) establish a collaborative US-USSR effort to improve and validate our methods of forecasting doses and dose commitments from the direct contamination of food sources, and (2) perform experiments and validation studies to improve our ability to predict rapidly and accurately the long-term internal dose from the contamination of agricultural soil. At early times following an accident, the direct contamination of pasture and food stuffs, particularly leafy vegetation and grain, can be of great importance. This situation has been modeled extensively. However, models employed then to predict the deposition, retention and transport of radionuclides in terrestrial environments employed concepts and data bases that were more than a decade old. The extent to which these models have been tested with independent data sets was limited. The data gathered in the former-USSR (and elsewhere throughout the Northern Hemisphere) offered a unique opportunity to test model predictions of wet and dry deposition, agricultural foodchain bioaccumulation, and short- and long-term retention, redistribution, and resuspension of radionuclides from a variety of natural and artificial surfaces. The current objective of this project is to evaluate and validate pathway-assessment models applicable to exposure and dose reconstruction at DOE facilities through use of international data sets. This project incorporates the activity of Task 7.lD into a multinational effort to evaluate models and data used for the prediction of radionuclide transfer through agricultural and aquatic systems to humans. It also includes participation in two studies, BIOMOVS (BIOspheric MOdel Validation Study) with the Swedish National Institute for Radiation Protection and VAMP (VAlidation of Model Predictions) with the International Atomic Energy Agency, that address testing the performance of models of radionuclide transport through foodchains

  12. Use of international data sets to evaluate and validate pathway assessment models applicable to exposure and dose reconstruction at DOE facilities. Monthly progress reports and final report, October--December 1994

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, F.O. [Senes Oak Ridge, Inc., TN (United States). Center for Risk Analysis

    1995-04-01

    The objective of Task 7.lD was to (1) establish a collaborative US-USSR effort to improve and validate our methods of forecasting doses and dose commitments from the direct contamination of food sources, and (2) perform experiments and validation studies to improve our ability to predict rapidly and accurately the long-term internal dose from the contamination of agricultural soil. At early times following an accident, the direct contamination of pasture and food stuffs, particularly leafy vegetation and grain, can be of great importance. This situation has been modeled extensively. However, models employed then to predict the deposition, retention and transport of radionuclides in terrestrial environments employed concepts and data bases that were more than a decade old. The extent to which these models have been tested with independent data sets was limited. The data gathered in the former-USSR (and elsewhere throughout the Northern Hemisphere) offered a unique opportunity to test model predictions of wet and dry deposition, agricultural foodchain bioaccumulation, and short- and long-term retention, redistribution, and resuspension of radionuclides from a variety of natural and artificial surfaces. The current objective of this project is to evaluate and validate pathway-assessment models applicable to exposure and dose reconstruction at DOE facilities through use of international data sets. This project incorporates the activity of Task 7.lD into a multinational effort to evaluate models and data used for the prediction of radionuclide transfer through agricultural and aquatic systems to humans. It also includes participation in two studies, BIOMOVS (BIOspheric MOdel Validation Study) with the Swedish National Institute for Radiation Protection and VAMP (VAlidation of Model Predictions) with the International Atomic Energy Agency, that address testing the performance of models of radionuclide transport through foodchains.

  13. Learning at work in Higher Vocational Education

    Directory of Open Access Journals (Sweden)

    Kerstin Littke

    2015-02-01

    Full Text Available Higher vocational training (HVE is a new form of post-secondary education that was introduced in 2009 in Sweden. The aim for HVE is to address the demands of a highly skilled Swedish workforce. Compared to other forms of adult and higher education it is less institutionalized and, based on Swedish standards, gives great opportunities for the provider to decide regarding the contents and design. The purpose of this study was to analyze a the quality of the course, Learning at Work (LIA, and (b to develop instruments and indicators to explore the quality of the student learning in working life as part of HVE. The design of research instruments was based on hypotheses to uncover the background, the learning process and effect parameters In LIA offered at 12 different HVE sites in Sweden within the areas of health care, computer science, technology and business administration. The survey data of forty-two students and thirty-six workplace supervisors were analyzed. The results of the study show that the quality of the learning at work (LIA varies considerably between different programs and different students. In most programs, it has a significant development potential. A well-functioning LIA is characterized by adequate learning content, an open work climate between colleagues, accuracy and dedication, frequent supervisor feedback, and regular communication between the Program Director and the supervisors. It is important that the educational provider requires workplaces with capacity to offer the students relevant and qualified work content. LIA should offer qualified work content providing knowledge of breadth and depth. Knowledge gained from school-based training should be challenged and must achieve curriculum goals. An important finding is the lack of definitions and criteria for quality, and the risk of quality differences between educational providers. Another significant problem identified in the study is the unclear division of

  14. Vocational Reintegration of Handicapped Workers with Assistive Devices

    Science.gov (United States)

    Cooper, N. E.

    1977-01-01

    Two approaches to vocational reintegration of handicapped workers are described: (1) adapting the disabled to the working environment through treatment, therapy, counseling, selective placement, and prostheses, and (2) adapting the working environment to particular handicaps, with the assistive device fitted to the machine or tool rather than to…

  15. Context-Driven Entrepreneurial Education in Vocational Schools

    Science.gov (United States)

    Sandirasegarane, Sharmila; Sutermaster, Staci; Gill, Alyssa; Volz, Jennifer; Mehta, Khanjan

    2016-01-01

    Vocational Education and Training (VET) is offered throughout the world to students of various educational backgrounds and career aspirations in an effort to create a skilled workforce. The structure of VET varies greatly across different fields and countries with high-growth, low-growth, and transitional economies. However, a common critique of…

  16. Welding. Module 8 of the Vocational Education Readiness Test (VERT).

    Science.gov (United States)

    Thomas, Edward L., Comp.

    Focusing on welding, this module is one of eight included in the Vocational Education Readiness Tests (VERT). The module begins by listing the objectives of the module and describing tools and equipment needed. The remainder of the module contains sections on manipulative skills, trade vocabulary, tool identification, trade computational skills,…

  17. Employment Outcomes of Vocational Rehabilitation Clients with Autism Spectrum Disorders

    Science.gov (United States)

    Alverson, Charlotte Y.; Yamamoto, Scott H.

    2017-01-01

    Research has consistently documented poor employment outcomes for young adults with autism spectrum disorder (ASD). Vocational rehabilitation (VR) services provide substantial federal and state commitments to individuals with disabilities to obtain and maintain employment. To date, little research has examined the relationship between VR services…

  18. Vocational Education in Corrections. Information Series No. 237.

    Science.gov (United States)

    Day, Sherman R.; McCane, Mel R.

    Vocational education programs in America's correctional institutions have been financially handicapped, since security demands the greatest portion of resource allocations. Four eras in the development of the correctional system are generally identified: era of punishment and retribution, era of restraint or reform, era of rehabilitation and…

  19. Vocational outcome of intervention for low-back pain

    NARCIS (Netherlands)

    van der Weide, W. E.; Verbeek, J. H.; van Tulder, M. W.

    1997-01-01

    Practical management guidelines for occupational health physicians are needed for the individual support of employees with low-back pain. In this study the level of evidence regarding the efficacy of intervention with vocational outcome parameters was assessed. In a systematic literature search, 40

  20. Vocational Training for Prison Inmates: A Treatment Model.

    Science.gov (United States)

    Uche, Greg N.

    1995-01-01

    Components of a treatment model are diagnosis of offenders' work history and training needs, in relation to labor market requirements; provision of appropriate job and entrepreneurial skills; and after care services. Focus is on vocational adjustment to ensure successful rehabilitation. (SK)

  1. Effects of Leadership Styles in Technical and Vocational Students, UTHM

    Science.gov (United States)

    Razak, Nur Afifah Binti Abdul; Hamidon, Nur Izeanty Binti

    2015-01-01

    Effective leadership helps our nation through times become a developed country. This study was undertaken to investigate the effects of leadership style among students in Technical and Vocational at University Tun Hussein Onn Malaysia. Descriptive study carried out to evaluate student leadership. The study sample consisted of 319 Technical and…

  2. Vocation, Motivation and Approaches to Learning: A Comparative Study

    Science.gov (United States)

    Arquero, Jose Luis; Fernández-Polvillo, Carmen; Hassall, Trevor; Joyce, John

    2015-01-01

    Purpose: The individual characteristics of students can have a strong influence on the success of the adopted innovations in terms of their transferability and sustainability. The purpose of this paper is to compare the motivations and approaches to learning on degrees with differing vocational components. Design/methodology/approach:…

  3. Conditions of Employment of Technical/Vocational Teachers.

    Science.gov (United States)

    Abrillo, Harry

    A study examined the job requirements and working conditions of vocational and technical education teachers (VTETs) in India, Indonesia, Malaysia, Singapore, and Thailand. Data were gathered (1) from published materials and interviews with officers and staff of concerned agencies and (2) from a project-developed questionnaire that was administered…

  4. Status of Technical and Vocational Education in Rural Institutions in ...

    African Journals Online (AJOL)

    This study was aimed at assessing the state of technical and vocational education in rural institutions in Delta State. Three research questions guided the study. A sample size of fifty (50) principals from 50 rural institutions in Delta State was used for the study. Data were collected using a questionnaire. The study reveals that ...

  5. Implementation of Technical and Vocational Training Strategy in ...

    African Journals Online (AJOL)

    Ethiopia introduced a wide range of socioeconomic development strategies, programs and practices since 1991. One of these is Agricultural Technical and Vocational Education and Training (ATVET) strategy that aims at producing extension agents (usually referred to as development agents /DAs/) who are capable to ...

  6. Re-Engineering Vocational and Technical Education for Sustainable ...

    African Journals Online (AJOL)

    Using the case of North Central Geo-Political Zone of Nigeria, this study interrogates the nexus between vocational and technical education (VTE) and sustainable development. Specific attention is put on provision and attainment of basic skills on one hand and job creation, self-employment, utilization of locally available ...

  7. Impact of Global Economic Crisis on Technical and Vocational ...

    African Journals Online (AJOL)

    The study examined the relationship between global economic crisis (GEC) and inadequacy of facilities for administration of the Technical and. Vocational Education. The descriptive survey design with a random sample of 100 technical teachers from a population of 139 technical teachers in all six Technical Colleges in ...

  8. Vocational Training and Professional Development: A Capability Perspective

    Science.gov (United States)

    Lambert, Marion; Vero, Josiane; Zimmermann, Benedicte

    2012-01-01

    Lifelong learning has become one of the keys to making workers' career paths more secure at both the French and the European policy level. However, the implementation of these policy lines raises delicate questions as to how the responsibility for vocational training should be shared among employees, employers and public institutions. The…

  9. Involving the Young: The German Approach to Vocational Education

    Science.gov (United States)

    Hirche, Walter

    2012-01-01

    Youth unemployment is a huge challenge for sustainable development in our societies. Statistics offer an alarming picture of the involvement of youth in the labour markets on a global scale. Germany, due to a strong tradition in vocational education and training deeply rooted in its culture, has very low rates of youth unemployment. The so-called…

  10. The Vocational Interests of a Sample of Optometry Students.

    Science.gov (United States)

    Emling, Robert C.; And Others

    1981-01-01

    The Strong-Campbell Interest Inventory, with a vocational title called Optometry, was used to profile a sample of second-year optometry students and to compare them with samples of practicing optometrists. One conclusion questions these students' compatibility with older practitioners. (MLW)

  11. Vocational Training for the Disabled in Taiwan, Republic of China.

    Science.gov (United States)

    Wu, Robert T. Y.

    For Taiwan, Republic of China, a nation with limited natural resources and a population of 22 million people in an area of only 36,000 square kilometers, the development and use of human resources plays a pivotal role in sustainable economic growth. Vocational education and training are two major human development methods. Since persons with…

  12. Maladaptive social behaviour of students in secondary vocational education

    NARCIS (Netherlands)

    Koerhuis, Marie-José

    2007-01-01

    The aim of this thesis was twofold: Firstly to create a reliable and valid new instrument to measure maladaptive social behaviour (MSB) of students in secondary vocational education, and secondly to assess which school context variables could predict MSB at school. Three data-waves were conducted

  13. Do Graduates of General Education in Uganda possess Vocational ...

    African Journals Online (AJOL)

    However, majority of students, particularly in the developing countries, enrol for general education programs that prepare them for white-colour jobs. A questionable aspect is whether these students have any vocation skills that would prepare them for job creation upon graduation. In this study, we provide insights into the ...

  14. Technical Education and Vocational Training in Developing Nations

    Science.gov (United States)

    Okolie, Ugochukwu Chinonso, Ed.

    2017-01-01

    Severe economic depression and the difficulty to acquire employment with adequate income have significant impact on a nation's social welfare. The need to provide ample educational opportunities is more imperative than ever, particularly in emerging economies. "Technical Education and Vocational Training in Developing Nations" is a…

  15. Skills for Employment: Scaling Up Technical and Vocational ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This project will help prepare youth in East and Southern Africa for economic opportunities, and improve the skills of new labour market entrants and existing workers. It will enhance the quality, relevance, and inclusiveness of technical and vocational education and training (TVET) in the region. Youth and job opportunities ...

  16. Personality, Vocational Interests, and Work Values of Medical Students

    Science.gov (United States)

    Duffy, Ryan D.; Borges, Nicole J.; Hartung, Paul J.

    2009-01-01

    Interests, personality, and values figure prominently in work motivation, yet little research has examined the combined influence of these factors on vocational behavior. The present study therefore examined relationships among these variables in a sample of 282 medical students (169 women, 113 men) who responded to the Strong Interest Inventory,…

  17. The Structure of Vocational Interests in Filipino Adolescents

    Science.gov (United States)

    Primavera, Michele T.; Church, A. Timothy; Katigbak, Marcia S.; Bruna, Lisa; White, Joy R.; Peradilla, Imelda

    2010-01-01

    The structure of vocational interests was investigated in Filipino high school students (N = 503), who rated their interest in 303 culture-relevant occupational titles and 93 major fields of study. Item-level principal components analyses identified general interest, prestige, and sex-type dimensions, rather than Prediger's (1982) People/Things…

  18. Historical evolution of vocational education in Denmark until 1945

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms; Bøndergaard, Gudmund

    2018-01-01

    of vocational training after the guild lost their control of apprenticeship system. The outcome of this process depended on the contentious interactions between the organisations of the artisans and the new industries, between the organisations of skilled and unskilled labour and not the least, the interests...

  19. Teachers’ Perceptions of Teaching in Workplace Simulations in Vocational Education

    NARCIS (Netherlands)

    Jossberger, Helen; Brand-Gruwel, Saskia; Van de Wiel, Margje; Boshuizen, Els

    2018-01-01

    In a large-scale top-down innovation operation in the Netherlands, workplace simulations have been implemented in vocational schools, where students are required to work independently and self-direct their learning. However, research has shown that the success of such large-scale top-down

  20. Financial Information 2016: Australian Vocational Education and Training Statistics

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2017

    2017-01-01

    This publication provides financial information on the government-funded vocational education and training (VET) system in Australia. Reporting includes VET funds transacted through government accounts of the Australian and state and territory government departments and their controlled training organisation entities such as TAFE institutes and…

  1. Training Vocational Rehabilitation Counselors in Group Dynamics: A Psychoeducational Model.

    Science.gov (United States)

    Elliott, Timothy R.

    1990-01-01

    Describes a six-session psychoeducational program for training vocational rehabilitation counselors in group dynamics. Presents evaluation of program by counselors (N=15) in which leadership styles, conflict management, and typology of group tasks concepts were rated as most beneficial. (Author/ABL)

  2. Skills for Employment: Scaling Up Technical and Vocational Training

    International Development Research Centre (IDRC) Digital Library (Canada)

    Many young people have little or no skills. They are excluded from productive economic and social life. Those with an education often have skills that do not match current demand in the labour market, where educational and skill requirements are increasing. Technical and vocational training African countries have put their ...

  3. The Vocational Guidance Research Database: A Scientometric Approach

    Science.gov (United States)

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the…

  4. The Researcher's Role in the Renewal of Vocational Education.

    Science.gov (United States)

    Asche, F. Marion

    1986-01-01

    The author argues that the potential effectiveness of researchers in the renewal of vocational education will depend in large measure on their ability to participate in the larger shift from total dependence on physical models of research and their ability to build new interdisciplinary models based in part on emerging practices in business and…

  5. Confidence Sharing in the Vocational Counselling Interview: Emergence and Repercussions

    Science.gov (United States)

    Olry-Louis, Isabelle; Bremond, Capucine; Pouliot, Manon

    2012-01-01

    Confidence sharing is an asymmetrical dialogic episode to which both parties consent, in which one reveals something personal to the other who participates in the emergence and unfolding of the confidence. We describe how this is achieved at a discursive level within vocational counselling interviews. Based on a corpus of 64 interviews, we analyse…

  6. Adolescent Street Boy Urchins and Vocational Training in Northern Nigeria

    Science.gov (United States)

    Usman, Lantana M.

    2009-01-01

    In northern Nigeria, over 80% of the unskilled and uneducated adolescent street boys, or "Almajiris", are from the ethnic Hausa-Fulani tribes. They depend on street begging and menial jobs for daily survival. In dealing with the situation, state vocational centers were established as the Millennium Hope Project (MHP) to provide the boys…

  7. Impact of vocational and entrepreneurship education on the ...

    African Journals Online (AJOL)

    This paper reports the findings of a study that delved into the impact of vocational and entrepreneurship education (VEE) on the economic growth of Ogun State, Nigeria. Specifically, the study investigated the extent to which VEE can enhance the economic growth of the state and the factors inhibiting its development.

  8. CRC Credential Attainment by State Vocational Rehabilitation Counselors

    Science.gov (United States)

    Harpster, Anna M.; Byers, Katherine L.; Harris, LaKeisha L.

    2011-01-01

    This study examines 137 state vocational rehabilitation (VR) counselors' perceptions of the value of having the Certified Rehabilitation Counselor (CRC) credential. While almost 53% of this sample included persons who were certified, the majority who were not indicated that the two major reasons for not currently having this designation were: (a)…

  9. Females in Vocational Education: Reflections of the Labor Market.

    Science.gov (United States)

    Lakes, Richard; Pritchard, Alice M.

    1991-01-01

    The fact that gender desegregation of vocational programs has not yet been achieved might be related to labor force occupational segregation by gender. Social theorists view schooling inequities as mirrors of social structure, whereby schools track students to maintain social stratification. Mirroring the labor market, education has segregated…

  10. Vocational interest, counselling, socioeconomic status and age as ...

    African Journals Online (AJOL)

    The aim of the study was to investigate the relationship between vocational interest, counselling, socio-economic status and age on re-entry of girls into school in Edo State. One research hypothesis was formulated to guide the study. The design was correlational. Five research instruments were used: they are the Modified ...

  11. Vocational Education and Training in Italy. Second Edition, 1999.

    Science.gov (United States)

    Alluli, Giorgio

    This monograph describes the Italian initial and continuing vocational education and training (VET) system and its qualitative and quantitative development. Chapter 1 outlines the general context of the VET system--both institutions and social and economic aspects. It provides facts and figures on such topics as demographic trends in Italy, the…

  12. Attitudes and Motivations of Vocational Teachers Regarding Program Improvement.

    Science.gov (United States)

    Greenan, James P.; Wu, Mingchang; Mustapha, Ramlee B.; Ncube, Lisa B.

    1998-01-01

    Secondary vocational teachers in Indiana (n=186) indicated they were motivated to improve programs by concern for students, professional growth, and desire to keep current. They believed that program improvement enhances professional development, but lacked time to plan for improvement and were skeptical about administrators' ability to reduce…

  13. Collaborative Business Planning in Initial Vocational Education and Training

    Science.gov (United States)

    Laine, Kati; Hämäläinen, Raija

    2015-01-01

    There is a growing demand to enhance entrepreneurship. This study aims at producing knowledge that can assist teachers in designing and supporting collaborative learning of entrepreneurship in vocational education. A qualitative case study approach was adopted. The outcome of this study provides a better understanding of the factors that hinder…

  14. Investment in Human Capital: Vocational vs. Academic Education

    Science.gov (United States)

    Orkodashvili, Mariam

    2008-01-01

    The dilemma of providing effective education particularly in developing countries with limited resources and ambiguous calculations of rates of return due to unstable economies and labour market fluctuations makes it an absolute necessity to consider costs and benefits associated both with academic and vocational education. Through argumentation…

  15. 19th Century Roots to the American Vocational Movement.

    Science.gov (United States)

    Law, Gordon F.

    Historical developments in the 18th and 19th centuries influenced the course of European and American education and the separate path of vocational education. The first of these developments was the emergence of schools as primary instruments for the transmission of knowledge and culture, as a result of the phenomenal growth of the American states…

  16. Vocational Education and Training in Denmark. First Edition.

    Science.gov (United States)

    Nielsen, Soren P.

    This monograph examines vocational education and training (VT) in Denmark. Section 1 presents background information/framework data on the following: Denmark's political and administrative structure; population, employment, and unemployment; and the Danish economy. In section 2, the history of VT in Denmark is traced from before 1870 to the…

  17. Philosophy of Vocational Education in China: A Historical Overview

    Science.gov (United States)

    Schmidtke, Carsten; Chen, Peng

    2012-01-01

    Historically, Chinese educational philosophy has been dominated by Confucianism and, since 1949, by Marxism. However, rapid industrialization, ideological demands, and loyalty to traditions have now led to a situation where various Western philosophies have been adopted into vocational education in hopes of moving the country forward without…

  18. Black-White Differences on the Vocational Preference Inventory

    Science.gov (United States)

    Doughtie, Eugene B.; And Others

    1976-01-01

    The Vocational Preference Inventory (VPI) was administered to black and white undergraduates. The overall VPI profiles of the two groups were significantly different. The black students scored higher on the Social, Conventional, Enterprising, Self-Control, Status, and Infrequency scales. The white students scored higher on the Masculinity scale.…

  19. Students' Preferred Characteristics of Learning Environments in Vocational Secondary Education

    Science.gov (United States)

    Placklé, Ingeborg; Könings, Karen D.; Jacquet, Wolfgang; Struyven, Katrien; Libotton, Arno; van Merriënboer, Jeroen J. G.; Engels, Nadine

    2014-01-01

    If teachers and teacher educators are willing to support the learning of students, it is important for them to learn what motivates students to engage in learning. Students have their own preferences on design characteristics of powerful learning environments in vocational education. We developed an instrument--the Inventory Powerful Learning…

  20. Development of apprenticeship model for vocational school based on entrepreneurship

    Science.gov (United States)

    Sunyoto, Widodo, Joko; Samsudi

    2018-03-01

    The purpose of this study is to develop an apprenticeship model that focuses on the preparation of graduates of Vocational School to become entrepreneurs (entrepreneurs). The study was conducted by using Research and Development (R & D) method. The subjects were five Vocational Schools (State and Private) in Central Java. Data were collected through interview method and questionnaire. There were 26 teachers of Vocational School involved as respondent. In this research has produced an entrepreneurship-based model that is ready to be implemented at Vocational School. All respondents (100%) support the implementation of the offered model. There is only a small difference in the determination apprentice place whether at the business or industry sector. Most respondents (92.7%) agreed that apprenticeship place is in the small industry where the students can learn entrepreneurship from the entrepreneur. The rest of 7.7% of respondents prefer conduct the apprenticeship in the middle to upper industry where they would experience a modern and complete facility. It can be concluded that this model can be implemented with partners in small, medium, and large industries with a record of students can learn directly aspects of management with business owners instead of learning the technical aspects to employees only.

  1. A Factor Analytic Validation of Holland's Vocational Preference Inventory

    Science.gov (United States)

    Di Scipio, William J.

    1974-01-01

    A principal components analysis was applied to a 135-item pool of the Holland Vocational Preference Inventory, Sixth Revision. The a priori clinical scales were partially upheld with differences attributed to the characteristics of the sample and sociopolitical time context during which the test was administered. (Author)

  2. Psychometric Characteristics of a Vocational Preference Inventory Short Form.

    Science.gov (United States)

    Lowman, Rodney L.; Schurman, Susan J.

    1982-01-01

    The psychometric properties of a revised version of Holland's Vocational Preference Inventory were assessed using federal government employees. Factor analyses, interscale correlations, measures of internal consistency, and criterion group profiles are presented. Evidence was supportive of the validity of the revised form. (Author/BW)

  3. Standardized Curriculum for Marketing and Cooperative Vocational Education.

    Science.gov (United States)

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized course titles and core contents for seven marketing and cooperative vocational education courses in Mississippi are provided: (1) marketing education, part one; (2) marketing education, part two; (3) fashion merchandising; (4) marketing cooperative education, part one; (5) marketing cooperative education, part two; (6) diversified…

  4. Primary and Secondary Labor Markets: Implications for Vocational Rehabilitation.

    Science.gov (United States)

    Hagner, David

    2000-01-01

    Reviews theoretical and empirical work in labor economics and the sociology of work relating to the segmentation of the labor market into a primary and a secondary sector and examines the implications for vocational rehabilitation. Transition into primary sector employment is explored as an important aspect of career development for individuals…

  5. Financial Information 2015. Australian Vocational Education and Training Statistics

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2016

    2016-01-01

    This publication provides information on how government-funded vocational education and training (VET) in Australia is financed and where the money is spent. Government-funded VET in the 2015 reporting year is broadly defined as all activity delivered by government providers and government-funded activity delivered by community education providers…

  6. Satellite Telecommunications and Their Potential for Vocational Education.

    Science.gov (United States)

    Grieve, Shelley; Singer, Norman M.

    This report summarizes the findings and implications of a study that examined the potential for expanded use of satellite-related telecommunications in vocational education, focusing on the short-term potential of satellites in the areas of instruction, training, administration, and governance. The investigation found that a variety of…

  7. Stratification, School-Work Linkages and Vocational Education

    Science.gov (United States)

    Ainsworth, James W.; Roscigno, Vincent J.

    2005-01-01

    Building on more classical status attainment and reproduction perspectives, this article examines the extent of class, race and gender inequality in high school vocational education, and the consequences for students' later educational and occupational trajectories. Analyses demonstrate significant class, race and gender disparities in vocational…

  8. Postsecondary Vocational Programs vs. Apprenticeships in American Culinary Arts.

    Science.gov (United States)

    VanLandingham, Paul G.

    The apprenticeship system in the United States is primarily a private institution, separate from vocational-technical schools. Apprenticeships establish their own guidelines as to the required course of study. Apprentices do not get licensed unless they successfully complete a written and practical exam. Culinary apprenticeships vary. Many large…

  9. The "Technical and Vocational Education Initiative": Enclaves in British Schools.

    Science.gov (United States)

    Saunders, Murray

    The Technical and Vocational Education Initiative (TVEI) is intended as a pilot, on a massive scale, of particular approaches, with a systematic need to identify TVEI effects on students, staff, resources, and curricula. TVEI has a strong tendency toward the development of pilot enclaves in terms of its administrative, curricular,…

  10. Life-History and Developmental Antecedents of Female Vocational Preferences.

    Science.gov (United States)

    Reichel, Laura S.; Muchinsky, Paul M.

    1995-01-01

    A group of 296 female undergraduates completed the Strong Interest Inventory, Biographical Questionnaire, Bem Sex-Role Inventory, and Self-Esteem Inventory. Life history was a better predictor of vocational interests than either sex-role orientation or self-esteem. The only significant exception was that Femininity correlated with interest in…

  11. Extended teams in vocational education : collaboration on the border

    NARCIS (Netherlands)

    Mazereeuw, Marco; Wopereis, Iwan; McKenney, Susan

    2016-01-01

    Extended Teams (ETs), in which teachers and workplace supervisors are jointly responsible for the quality of education, were established to solve problems concerning school–workplace connections in vocational and professional education. Six ETs were investigated during their 1st year of

  12. Extended teams in vocational education: Collaboration on the border

    NARCIS (Netherlands)

    Mazereeuw, Marco; Wopereis, Iwan; McKenney, Susan

    2018-01-01

    Extended Teams (ETs), in which teachers and workplace supervisors are jointly responsible for the quality of education, were established to solve problems concerning school–workplace connections in vocational and professional education. Six ETs were investigated during their 1st year of

  13. Systemic Modelling for Relating Labour Market to Vocational Education

    Science.gov (United States)

    Papakitsos, Evangelos C.

    2016-01-01

    The present study introduces a systemic model that demonstrates a description of the relationship between the labour-market and vocational education from the perspective of systemic theory. Based on the application of the relevant methodology, the two open social systems are identified and analyzed. Their key-features are presented and the points…

  14. Students' Experiences of Ability-Based Streaming in Vocational Education

    Science.gov (United States)

    Tanggaard, Lene; Nielsen, Klaus; Jørgensen, Christian Helms

    2015-01-01

    Purpose: Since 2007, it has been mandatory for all vocational schools in Denmark to assess the prior qualifications of all students when they begin at the school and to use this assessment to divide students into different ability-based courses (streaming) with the aim of increasing the retention of students. The purpose of this paper is to…

  15. Motivation in vocational education: a reform issue in tertiary ...

    African Journals Online (AJOL)

    Working in a non-motivating environment is a nagging issue in various tertiary institutions in Cross River State .This dampens staff morale a great deal. However, the provision of motivation in work places will be a great boost to staff morale especially in Vocational Education. This paper discusses the meaning of motivation, ...

  16. Vocational Education and Skills Training in Mainland Tanzania for ...

    African Journals Online (AJOL)

    The development of any country Tanzania included depends on availability and effective utilization of human resources, which in turn are predicated on the level, quantity and quality of education, especially vocational and technical education and skills attained through formal and informal education, living and working ...

  17. Business as a Vocation: Catholic Social Teaching and Business Education

    Science.gov (United States)

    Turkson, Peter K. A.

    2012-01-01

    Building on "Vocation of the Business Leader," the recently released document from the Pontifical Council for Justice and Peace, along with input from Catholic business and educational leaders from around the world, this essay examines five pillars on which a Catholic business school should build its mission: foundations; the purpose of…

  18. The Genesis and Evolution of Pre-vocational Education: England.

    Science.gov (United States)

    Marshall, Stephanie

    1990-01-01

    Traces the history of English prevocational education since 1870, examining four pieces of educational legislation. Outlines the recurring debate over the extent utilitarianism should define education. Focuses on political and economic requirements that fostered utilitarianism. Evaluates the act's technical and vocational education initiative. (CH)

  19. Perspectives of New Trades Tutors: Boundary Crossing between Vocational Identities

    Science.gov (United States)

    Chan, Selena

    2012-01-01

    This article reports on a study of the perspectives of new tutors teaching traditional vocational trades who recently commenced teaching in the Institutes of Technologies and Polytechnics (ITPs) sector in New Zealand. The perspectives are collated from questionnaires and interviews of 13 tutors, from five ITPs, who have been teaching full-time for…

  20. Forms of School Experience in France's Vocational Training Track Students

    Science.gov (United States)

    Capdevielle-Mougnibas, Valérie; Courtinat-Camps, Amélie

    2017-01-01

    This article examines the existing relations between the social background, the cognitive skills, the sense of schooling experience, the relation to learning and the professional project in the construction of the meaning of their course choice for French boys living in working-class families and guided to vocational studies. It presents the…