WorldWideScience

Sample records for virus life cycle

  1. Hepatitis C virus: virology and life cycle

    Directory of Open Access Journals (Sweden)

    Chang Wook Kim

    2013-03-01

    Full Text Available Hepatitis C virus (HCV is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can progress to severe liver disease including cirrhosis and hepatocellular carcinoma. In the last decade, our basic understanding of HCV virology and life cycle has advanced greatly with the development of HCV cell culture and replication systems. Our ability to treat HCV infection has also been improved with the combined use of interferon, ribavirin and small molecule inhibitors of the virally encoded NS3/4A protease, although better therapeutic options are needed with greater antiviral efficacy and less toxicity. In this article, we review various aspects of HCV life cycle including viral attachment, entry, fusion, viral RNA translation, posttranslational processing, HCV replication, viral assembly and release. Each of these steps provides potential targets for novel antiviral therapeutics to cure HCV infection and prevent the adverse consequences of progressive liver disease.

  2. PETRI NET MODELING OF COMPUTER VIRUS LIFE CYCLE

    African Journals Online (AJOL)

    Dr Obe

    ABSTRACT. Virus life cycle, which refers to the stages of development of a computer virus, is presented as a suitable area for the application of Petri nets. Petri nets a powerful modeling tool in the field of dynamic system analysis is applied to model the virus life cycle. Simulation of the derived model is also presented.

  3. Petri Net Modeling of Computer Virus Life Cycle | Ikekonwu ...

    African Journals Online (AJOL)

    Virus life cycle, which refers to the stages of development of a computer virus, is presented as a suitable area for the application of Petri nets. Petri nets a powerful modeling tool in the field of dynamic system analysis is applied to model the virus life cycle. Simulation of the derived model is also presented. The intention of ...

  4. PETRI NET MODELING OF COMPUTER VIRUS LIFE CYCLE

    African Journals Online (AJOL)

    Dr Obe

    Virus life cycle, which refers to the stages of development of a computer virus, is presented as a suitable area for the application of Petri ... used to derive anti-viral programs based on the Petri net framework. Keywords: Virus lifecycle, Petri nets, ... are often disguised as images, joke software or anti-virus software. We have ...

  5. Aeginetia indica Decoction Inhibits Hepatitis C Virus Life Cycle.

    Science.gov (United States)

    Lin, Cheng-Wei; Lo, Chieh-Wen; Tsai, Chia-Ni; Pan, Ting-Chun; Chen, Pin-Yin; Yu, Ming-Jiun

    2018-01-09

    Chronic hepatitis C virus (HCV) infection is still a global epidemic despite the introduction of several highly effective direct-acting antivirals that are tagged with sky-high prices. The present study aimed to identify an herbal decoction that ameliorates HCV infection. Among six herbal decoctions tested, the Aeginetia indica decoction had the most profound effect on the HCV reporter activity in infected Huh7.5.1 liver cells in a dose- and time-dependent manner. The Aeginetia indica decoction exerted multiple inhibitory effects on the HCV life cycle. Pretreatment of the cells with the Aeginetia indica decoction prior to HCV infection reduced the HCV RNA and non-structural protein 3 (NS3) protein levels in the infected cells. The Aeginetia indica decoction reduced HCV internal ribosome entry site-mediated protein translation activity. It also reduced the HCV RNA level in the infected cells in association with reduced NS5A phosphorylation at serine 235, a predominant phosphorylation event indispensable to HCV replication. Thus, the Aeginetia indica decoction inhibits HCV infection, translation, and replication. Mechanistically, the Aeginetia indica decoction probably reduced HCV replication via reducing NS5A phosphorylation at serine 235.

  6. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle.

    Science.gov (United States)

    Bornholdt, Zachary A; Noda, Takeshi; Abelson, Dafna M; Halfmann, Peter; Wood, Malcolm R; Kawaoka, Yoshihiro; Saphire, Erica Ollmann

    2013-08-15

    Proteins, particularly viral proteins, can be multifunctional, but the mechanisms behind multifunctionality are not fully understood. Here, we illustrate through multiple crystal structures, biochemistry, and cellular microscopy that VP40 rearranges into different structures, each with a distinct function required for the ebolavirus life cycle. A butterfly-shaped VP40 dimer traffics to the cellular membrane. Once there, electrostatic interactions trigger rearrangement of the polypeptide into a linear hexamer. These hexamers construct a multilayered, filamentous matrix structure that is critical for budding and resembles tomograms of authentic virions. A third structure of VP40, formed by a different rearrangement, is not involved in virus assembly but instead uniquely binds RNA to regulate viral transcription inside infected cells. These results provide a functional model for ebolavirus matrix assembly and the other roles of VP40 in the virus life cycle and demonstrate how a single wild-type, unmodified polypeptide can assemble into different structures for different functions. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Isolation and life cycle characterization of lytic viruses infecting heterotrophic bacteria and cyanobacteria

    DEFF Research Database (Denmark)

    Middelboe, Mathias; Chan, Amy; Bertelsen, Sif Koldborg

    2010-01-01

    Basic knowledge on viruses infecting heterotrophic bacteria and cyanobacteria is key to future progress in understanding the role of viruses in aquatic systems and the influence of virus–host interactions on microbial mortality, biogeochemical cycles, and genetic exchange. Such studies require...... infecting such hosts. In addition to the isolation procedures, methods for life cycle characterization (one-step growth experiments) of bacteriophages and cyanophages are described. Finally, limitations and drawbacks of the proposed methods are assessed and discussed...

  8. Multiple effects of toxins isolated from Crotalus durissus terrificus on the hepatitis C virus life cycle.

    Science.gov (United States)

    Shimizu, Jacqueline Farinha; Pereira, Carina Machado; Bittar, Cintia; Batista, Mariana Nogueira; Campos, Guilherme Rodrigues Fernandes; da Silva, Suely; Cintra, Adélia Cristina Oliveira; Zothner, Carsten; Harris, Mark; Sampaio, Suely Vilela; Aquino, Victor Hugo; Rahal, Paula; Jardim, Ana Carolina Gomes

    2017-01-01

    Hepatitis C virus (HCV) is one of the main causes of liver disease and transplantation worldwide. Current therapy is expensive, presents additional side effects and viral resistance has been described. Therefore, studies for developing more efficient antivirals against HCV are needed. Compounds isolated from animal venoms have shown antiviral activity against some viruses such as Dengue virus, Yellow fever virus and Measles virus. In this study, we evaluated the effect of the complex crotoxin (CX) and its subunits crotapotin (CP) and phospholipase A2 (PLA2-CB) isolated from the venom of Crotalus durissus terrificus on HCV life cycle. Huh 7.5 cells were infected with HCVcc JFH-1 strain in the presence or absence of these toxins and virus was titrated by focus formation units assay or by qPCR. Toxins were added to the cells at different time points depending on the stage of virus life cycle to be evaluated. The results showed that treatment with PLA2-CB inhibited HCV entry and replication but no effect on HCV release was observed. CX reduced virus entry and release but not replication. By treating cells with CP, an antiviral effect was observed on HCV release, the only stage inhibited by this compound. Our data demonstrated the multiple antiviral effects of toxins from animal venoms on HCV life cycle.

  9. Dengue virus life cycle : viral and host factors modulating infectivity

    NARCIS (Netherlands)

    Rodenhuis-Zybert, Izabela A.; Wilschut, Jan; Smit, Jolanda M.

    Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen. All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50-100 million individuals annually. Whereas the majority of DENV infections proceed asymptomatically or result in self-limited

  10. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle

    National Research Council Canada - National Science Library

    Bornholdt, Zachary A; Noda, Takeshi; Abelson, Dafna M; Halfmann, Peter; Wood, Malcolm R; Kawaoka, Yoshihiro; Saphire, Erica Ollmann

    2013-01-01

    .... Here, we illustrate through multiple crystal structures, biochemistry, and cellular microscopy that VP40 rearranges into different structures, each with a distinct function required for the ebolavirus life cycle...

  11. Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney

    Directory of Open Access Journals (Sweden)

    Asako Murayama

    2016-06-01

    Full Text Available A hepatitis C virus (HCV cell culture system incorporating the JFH-1 strain and the human hepatoma cell line HuH-7 enabled the production of infectious HCV particles. Several host factors were identified as essential for HCV replication. Supplementation of these factors in nonhepatic human cell lines enabled HCV replication and particle production. Vero cells established from monkey kidney are commonly used for the production of vaccines against a variety of viruses. In this study, we aimed to establish a novel Vero cell line to reconstruct the HCV life cycle. Unmodified Vero cells did not allow HCV infection or replication. The expression of microRNA 122 (miR-122, an essential factor for HCV replication, is notably low in Vero cells. Therefore, we supplemented Vero cells with miR-122 and found that HCV replication was enhanced. However, Vero cells that expressed miR-122 still did not allow HCV infection. We supplemented HCV receptor molecules and found that scavenger receptor class B type I (SRBI was essential for HCV infection in Vero cells. The supplementation of apolipoprotein E (ApoE, a host factor important for virus production, enabled the production of infectious virus in Vero cells. Finally, we created a Vero cell line that expressed the essential factors miR-122, SRBI, and ApoE; the entire HCV life cycle, including infection, replication, and infectious virus production, was completed in these cells. In conclusion, we demonstrated that miR-122, SRBI, and ApoE were necessary and sufficient for the completion of the entire HCV life cycle in nonhuman, nonhepatic Vero cells.

  12. Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney.

    Science.gov (United States)

    Murayama, Asako; Sugiyama, Nao; Wakita, Takaji; Kato, Takanobu

    2016-06-14

    A hepatitis C virus (HCV) cell culture system incorporating the JFH-1 strain and the human hepatoma cell line HuH-7 enabled the production of infectious HCV particles. Several host factors were identified as essential for HCV replication. Supplementation of these factors in nonhepatic human cell lines enabled HCV replication and particle production. Vero cells established from monkey kidney are commonly used for the production of vaccines against a variety of viruses. In this study, we aimed to establish a novel Vero cell line to reconstruct the HCV life cycle. Unmodified Vero cells did not allow HCV infection or replication. The expression of microRNA 122 (miR-122), an essential factor for HCV replication, is notably low in Vero cells. Therefore, we supplemented Vero cells with miR-122 and found that HCV replication was enhanced. However, Vero cells that expressed miR-122 still did not allow HCV infection. We supplemented HCV receptor molecules and found that scavenger receptor class B type I (SRBI) was essential for HCV infection in Vero cells. The supplementation of apolipoprotein E (ApoE), a host factor important for virus production, enabled the production of infectious virus in Vero cells. Finally, we created a Vero cell line that expressed the essential factors miR-122, SRBI, and ApoE; the entire HCV life cycle, including infection, replication, and infectious virus production, was completed in these cells. In conclusion, we demonstrated that miR-122, SRBI, and ApoE were necessary and sufficient for the completion of the entire HCV life cycle in nonhuman, nonhepatic Vero cells. HCV is a major cause of chronic liver diseases worldwide, and an effective prophylactic HCV vaccine is needed. For safety reasons, the current HCV cell culture system using HuH-7 cells, which was established from a hepatocellular carcinoma, is not suitable for the production of a vaccine against HCV. A robust HCV production system using non-cancer-derived cells is indispensable for

  13. Regulation of core expression during the hepatitis C virus life cycle.

    Science.gov (United States)

    Afzal, Muhammad Sohail; Alsaleh, Khaled; Farhat, Rayan; Belouzard, Sandrine; Danneels, Adeline; Descamps, Véronique; Duverlie, Gilles; Wychowski, Czeslaw; Zaidi, Najam us Sahar Sadaf; Dubuisson, Jean; Rouillé, Yves

    2015-02-01

    Core plays a critical role during hepatitis C virus (HCV) assembly, not only as a structural component of the virion, but also as a regulator of the formation of assembly sites. In this study, we observed that core is expressed later than other HCV proteins in a single viral cycle assay, resulting in a relative increase of core expression during a late step of the viral life cycle. This delayed core expression results from an increase of core half-life, indicating that core is initially degraded and is stabilized at a late step of the HCV life cycle. Stabilization-mediated delayed kinetics of core expression were also observed using heterologous expression systems. Core stabilization did not depend on its interaction with non-structural proteins or lipid droplets but was correlated with its expression levels and its oligomerization status. Therefore in the course of a HCV infection, core stabilization is likely to occur when the prior amplification of the viral genome during an initial replication step allows core to be synthesized at higher levels as a stable protein, during the assembly step of the viral life cycle. © 2015 The Authors.

  14. Dynamic Phosphorylation of VP30 Is Essential for Ebola Virus Life Cycle.

    Science.gov (United States)

    Biedenkopf, Nadine; Lier, Clemens; Becker, Stephan

    2016-05-15

    Ebola virus is the causative agent of a severe fever with high fatality rates in humans and nonhuman primates. The regulation of Ebola virus transcription and replication currently is not well understood. An important factor regulating viral transcription is VP30, an Ebola virus-specific transcription factor associated with the viral nucleocapsid. Previous studies revealed that the phosphorylation status of VP30 impacts viral transcription. Together with NP, L, and the polymerase cofactor VP35, nonphosphorylated VP30 supports viral transcription. Upon VP30 phosphorylation, viral transcription ceases. Phosphorylation weakens the interaction between VP30 and the polymerase cofactor VP35 and/or the viral RNA. VP30 thereby is excluded from the viral transcription complex, simultaneously leading to increased viral replication which is supported by NP, L, and VP35 alone. Here, we use an infectious virus-like particle assay and recombinant viruses to show that the dynamic phosphorylation of VP30 is critical for the cotransport of VP30 with nucleocapsids to the sites of viral RNA synthesis, where VP30 is required to initiate primary viral transcription. We further demonstrate that a single serine residue at amino acid position 29 was sufficient to render VP30 active in primary transcription and to generate a recombinant virus with characteristics comparable to those of wild-type virus. In contrast, the rescue of a recombinant virus with a single serine at position 30 in VP30 was unsuccessful. Our results indicate critical roles for phosphorylated and dephosphorylated VP30 during the viral life cycle. The current Ebola virus outbreak in West Africa has caused more than 28,000 cases and 11,000 fatalities. Very little is known regarding the molecular mechanisms of how the Ebola virus transcribes and replicates its genome. Previous investigations showed that the transcriptional support activity of VP30 is activated upon VP30 dephosphorylation. The current study reveals that

  15. The Telomerase Inhibitor MST-312 Interferes with Multiple Steps in the Herpes Simplex Virus Life Cycle.

    Science.gov (United States)

    Haberichter, Jarod; Roberts, Scott; Abbasi, Imran; Dedthanou, Phonphanh; Pradhan, Prajakta; Nguyen, Marie L

    2015-10-01

    The life cycle of herpes simplex virus (HSV) has the potential to be further manipulated to yield novel, more effective therapeutic treatments. Recent research has demonstrated that HSV-1 can increase telomerase activity and that expression of the catalytic component of telomerase, telomerase reverse transcriptase (TERT), alters sensitivity to HSV-dependent apoptosis. Telomerase is a cellular enzyme that synthesizes nucleotide repeats at the ends of chromosomes (telomeres), which prevents shortening of the 3' ends of DNA with each cell division. Once telomeres reach a critical length, cells undergo senescence and apoptosis. Here, we used a cell-permeable, reversible inhibitor of the telomerase enzyme, MST-312, to investigate telomerase activity during HSV infection. Human mammary epithelial cells immortalized through TERT expression and human carcinoma HEp-2 cells were infected with the KOS1.1 strain of HSV-1 in the presence of MST-312. MST-312 treatment reduced the number of cells displaying a cytopathic effect and the accumulation of immediate early and late viral proteins. Moreover, the presence of 20 μM to 100 μM MST-312 during infection led to a 2.5- to 5.5-log10 decrease in viral titers. MST-312 also inhibited the replication of HSV-2 and a recent clinical isolate of HSV-1. Additionally, we determined that MST-312 has the largest impact on viral events that take place prior to 5 h postinfection (hpi). Furthermore, MST-312 treatment inhibited virus replication, as measured by adsorption assays and quantification of genome replication. Together, these findings demonstrate that MST-312 interferes with the HSV life cycle. Further investigation into the mechanism for MST-312 is warranted and may provide novel targets for HSV therapies. Herpes simplex virus (HSV) infections can lead to cold sores, blindness, and brain damage. Identification of host factors that are important for the virus life cycle may provide novel targets for HSV antivirals. One such factor

  16. Eilat virus host range restriction is present at multiple levels of the virus life cycle.

    Science.gov (United States)

    Nasar, Farooq; Gorchakov, Rodion V; Tesh, Robert B; Weaver, Scott C

    2015-01-15

    Most alphaviruses are mosquito-borne and exhibit a broad host range, infecting many different vertebrates, including birds, rodents, equids, humans, and nonhuman primates. This ability of most alphaviruses to infect arthropods and vertebrates is essential for their maintenance in nature. Recently, a new alphavirus, Eilat virus (EILV), was described, and in contrast to all other mosquito-borne viruses, it is unable to replicate in vertebrate cell lines. Investigations into the nature of its host range restriction showed the inability of genomic EILV RNA to replicate in vertebrate cells. Here, we investigated whether the EILV host range restriction is present at the entry level and further explored the viral factors responsible for the lack of genomic RNA replication. Utilizing Sindbis virus (SINV) and EILV chimeras, we show that the EILV vertebrate host range restriction is also manifested at the entry level. Furthermore, the EILV RNA replication restriction is independent of the 3' untranslated genome region (UTR). Complementation experiments with SINV suggested that RNA replication is restricted by the inability of the EILV nonstructural proteins to form functional replicative complexes. These data demonstrate that the EILV host range restriction is multigenic, involving at least one gene from both nonstructural protein (nsP) and structural protein (sP) open reading frames (ORFs). As EILV groups phylogenetically within the mosquito-borne virus clade of pathogenic alphaviruses, our findings have important evolutionary implications for arboviruses. Our work explores the nature of host range restriction of the first "mosquito-only alphavirus," EILV. EILV is related to pathogenic mosquito-borne viruses (Eastern equine encephalitis virus [EEEV], Western equine encephalitis virus [WEEV], Venezuelan equine encephalitis virus [VEEV], and Chikungunya virus [CHIKV]) that cause severe disease in humans. Our data demonstrate that EILV is restricted both at entry and genomic

  17. A novel life cycle modeling system for Ebola virus shows a genome length-dependent role of VP24 in virus infectivity.

    Science.gov (United States)

    Watt, Ari; Moukambi, Felicien; Banadyga, Logan; Groseth, Allison; Callison, Julie; Herwig, Astrid; Ebihara, Hideki; Feldmann, Heinz; Hoenen, Thomas

    2014-09-01

    Work with infectious Ebola viruses is restricted to biosafety level 4 (BSL4) laboratories, presenting a significant barrier for studying these viruses. Life cycle modeling systems, including minigenome systems and transcription- and replication-competent virus-like particle (trVLP) systems, allow modeling of the virus life cycle under BSL2 conditions; however, all current systems model only certain aspects of the virus life cycle, rely on plasmid-based viral protein expression, and have been used to model only single infectious cycles. We have developed a novel life cycle modeling system allowing continuous passaging of infectious trVLPs containing a tetracistronic minigenome that encodes a reporter and the viral proteins VP40, VP24, and GP1,2. This system is ideally suited for studying morphogenesis, budding, and entry, in addition to genome replication and transcription. Importantly, the specific infectivity of trVLPs in this system was ∼ 500-fold higher than that in previous systems. Using this system for functional studies of VP24, we showed that, contrary to previous reports, VP24 only very modestly inhibits genome replication and transcription when expressed in a regulated fashion, which we confirmed using infectious Ebola viruses. Interestingly, we also discovered a genome length-dependent effect of VP24 on particle infectivity, which was previously undetected due to the short length of monocistronic minigenomes and which is due at least partially to a previously unknown function of VP24 in RNA packaging. Based on our findings, we propose a model for the function of VP24 that reconciles all currently available data regarding the role of VP24 in nucleocapsid assembly as well as genome replication and transcription. Ebola viruses cause severe hemorrhagic fevers in humans, with no countermeasures currently being available, and must be studied in maximum-containment laboratories. Only a few of these laboratories exist worldwide, limiting our ability to study

  18. Animals in the Zika Virus Life Cycle: What to Expect from Megadiverse Latin American Countries.

    Science.gov (United States)

    Bueno, Marina Galvão; Martinez, Nádia; Abdalla, Lívia; Duarte Dos Santos, Claudia Nunes; Chame, Marcia

    2016-12-01

    Zika virus (ZIKV) was first isolated in 1947 in primates in Uganda, West Africa. The virus remained confined to the equatorial regions of Africa and Asia, cycling between infecting monkeys, arboreal mosquitoes, and occasionally humans. The ZIKV Asiatic strain was probably introduced into Brazil in or around late 2013. Presently, ZIKV is in contact with the rich biodiversity in all Brazilian biomes, bordering on other Latin American countries. Infections in Brazilian primates have been reported recently, but the overall impact of this virus on wildlife in the Americas is still unknown. The current epidemic in the Americas requires knowledge on the role of mammals, especially nonhuman primates (NHPs), in ZIKV transmission to humans. The article discusses the available data on ZIKV in host animals and issues of biodiversity, rapid environmental change, and impact on human health in megadiverse Latin American countries. The authors reviewed scientific articles and recent news stories on ZIKV in animals, showing that 47 animal species from three orders (mammals, reptiles, and birds) have been investigated for the potential to establish a sylvatic cycle. The review aims to contribute to epidemiological studies and the knowledge on the natural history of ZIKV. The article concludes with questions that require urgent attention in epidemiological studies involving wildlife in order to understand their role as ZIKV hosts and to effectively control the epidemic.

  19. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies

    DEFF Research Database (Denmark)

    Scheel, Troels K H; Rice, Charles M

    2013-01-01

    More than two decades of intense research has provided a detailed understanding of hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has paved the way for the development of antiviral compounds to spare patients from life-threatening liver disease....... An exciting new era in HCV therapy dawned with the recent approval of two viral protease inhibitors, used in combination with pegylated interferon-α and ribavirin; however, this is just the beginning. Multiple classes of antivirals with distinct targets promise highly efficient combinations, and interferon...

  20. Life cycle assessment (LCA)

    DEFF Research Database (Denmark)

    Thrane, Mikkel; Schmidt, Jannick Andresen

    2004-01-01

    The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards.......The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards....

  1. Molecular studies on IAV nucleoprotein: interaction with host factors and its role in virus life cycle

    OpenAIRE

    Batra, Jyoti

    2017-01-01

    Influenza A viruses (IAV) are obligate intracellular pathogens, causing substantial health and economic impacts worldwide. Like other RNA viruses, IAV greatly rely on the exploitation and subversion of host cellular proteins and pathways to facilitate virus replication. Insight into the molecular biology of these relationships could lead to novel antiviral strategies and has the potential to identify host specific interactions that would act as a barrier to pandemic emergence. IAV genom...

  2. Life Cycle Costing.

    Science.gov (United States)

    McCraley, Thomas L.

    1985-01-01

    Life cycle costing establishes a realistic comparison of the cost of owning and operating products. The formula of initial cost plus maintenance plus operation divided by useful life identifies the best price over the lifetime of the product purchased. (MLF)

  3. Contribution of Sec61α to the Life Cycle of Ebola Virus

    OpenAIRE

    Iwasa, Ayaka; Halfmann, Peter; Noda, Takeshi; Oyama, Masaaki; Kozuka-Hata, Hiroko; Watanabe, Shinji; Shimojima, Masayuki; Watanabe, Tokiko; Kawaoka, Yoshihiro

    2011-01-01

    Background. Similar to other viruses, the viral proteins of Ebola virus (EBOV) interact with a variety of host proteins for its replication. Of the 7 structural proteins encoded in the EBOV genome, VP24 is the smallest and is multifunctional.

  4. Life Cycle Environmental Management

    DEFF Research Database (Denmark)

    Pedersen, Claus Stig; Jørgensen, Jørgen; Pedersen, Morten Als

    1996-01-01

    processes. The discipline of life cycle environmental management (LCEM) focuses on the incorporation of environmental criteria from the life cycles of products and other company activities into the company management processes. This paper introduces the concept of LCEM as an important element...

  5. Life Cycle Impact Assessment

    DEFF Research Database (Denmark)

    Rosenbaum, Ralph K.; Hauschild, Michael Zwicky; Boulay, Anne-Marie

    2017-01-01

    This chapter is dedicated to the third phase of an LCA study, the Life Cycle Impact Assessment (LCIA) where the life cycle inventory’s information on elementary flows is translated into environmental impact scores. In contrast to the three other LCA phases, LCIA is in practice largely automated...

  6. Life cycle management (LCM)

    DEFF Research Database (Denmark)

    Remmen, Arne; Thrane, Mikkel

    2004-01-01

    The chapter gives an introduction to Life Cycle Management (LCM) and shows how LCM can be practiced in different contexts and at different ambition levels.......The chapter gives an introduction to Life Cycle Management (LCM) and shows how LCM can be practiced in different contexts and at different ambition levels....

  7. Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses

    Science.gov (United States)

    Chahar, Harendra Singh; Bao, Xiaoyong; Casola, Antonella

    2015-01-01

    Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from. These vesicles participate in cell-to-cell communication and transfer of biologically active proteins, lipids, and RNAs. Their role in viral infections is just beginning to be appreciated. RNA viruses are an important class of pathogens and affect millions of people worldwide. Recent studies on Human Immunodeficiency Virus (HIV), Hepatitis C Virus (HCV), human T-cell lymphotropic virus (HTLV), and Dengue Virus (DENV) have demonstrated that exosomes released from infected cells harbor and deliver many regulatory factors including viral RNA and proteins, viral and cellular miRNA, and other host functional genetic elements to neighboring cells, helping to establish productive infections and modulating cellular responses. Exosomes can either spread or limit an infection depending on the type of pathogen and target cells, and can be exploited as candidates for development of antiviral or vaccine treatments. This review summarizes recent progress made in understanding the role of exosomes in RNA virus infections with an emphasis on their potential contribution to pathogenesis. PMID:26102580

  8. Life Cycle Management

    DEFF Research Database (Denmark)

    Bey, Niki

    2017-01-01

    This chapter gives an overview of Life Cycle Management (LCM)—a discipline that deals with the managerial tasks related to practicing sustainable development in an organisation . Just as Life Cycle Assessment, LCM advocates the life cycle perspective , and it applies this perspective in decision......-making processes. The chapter shows that LCA can play a key role in LCM since LCA provides quantitative performance measurements. It also explains, which stakeholders need to be considered, how LCA and LCM relate, how LCA can be used to develop Key Performance Indicators, and addresses how LCM can be integrated...

  9. Product Life Cycle Planning

    National Research Council Canada - National Science Library

    Walaszek, Jeffrey

    2003-01-01

    .... This phase of work was undertaken to: (1) provide guidelines, technical support, and planning approaches for researchers that result in realistic life cycle plans for products emerging from the RSM...

  10. Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.

    Science.gov (United States)

    Sommer, Andreas F R; Rivière, Lise; Qu, Bingqian; Schott, Kerstin; Riess, Maximilian; Ni, Yi; Shepard, Caitlin; Schnellbächer, Esther; Finkernagel, Malin; Himmelsbach, Kiyoshi; Welzel, Karin; Kettern, Nadja; Donnerhak, Christian; Münk, Carsten; Flory, Egbert; Liese, Juliane; Kim, Baek; Urban, Stephan; König, Renate

    2016-05-27

    Deoxynucleotide triphosphates (dNTPs) are essential for efficient hepatitis B virus (HBV) replication. Here, we investigated the influence of the restriction factor SAMHD1, a dNTP hydrolase (dNTPase) and RNase, on HBV replication. We demonstrated that silencing of SAMHD1 in hepatic cells increased HBV replication, while overexpression had the opposite effect. SAMHD1 significantly affected the levels of extracellular viral DNA as well as intracellular reverse transcription products, without affecting HBV RNAs or cccDNA. SAMHD1 mutations that interfere with the dNTPase activity (D137N) or in the catalytic center of the histidine-aspartate (HD) domain (D311A), and a phospho-mimetic mutation (T592E), abrogated the inhibitory activity. In contrast, a mutation diminishing the potential RNase but not dNTPase activity (Q548A) and a mutation disabling phosphorylation (T592A) did not affect antiviral activity. Moreover, HBV restriction by SAMHD1 was rescued by addition of deoxynucleosides. Although HBV infection did not directly affect protein level or phosphorylation of SAMHD1, the virus upregulated intracellular dATPs. Interestingly, SAMHD1 was dephosphorylated, thus in a potentially antiviral-active state, in primary human hepatocytes. Furthermore, SAMHD1 was upregulated by type I and II interferons in hepatic cells. These results suggest that SAMHD1 is a relevant restriction factor for HBV and restricts reverse transcription through its dNTPase activity.

  11. The life cycle of a virus: the infectious disease narrative of NDM-1.

    Science.gov (United States)

    Mason, Alicia M; Wright, Kevin B

    2015-01-01

    This study is a report of a two-part content analysis of domestic and international print news reports (over a 3-year period) that examined how the nature of the New Delhi Metallo-beta-lactamase-1 (NDM-1) virus and the severity of the threat were conveyed to global audiences. In particular, the authors focused on the ongoing crisis narrative of NDM-1 and the potentially negative outcomes of international communication warning and false alarm systems regarding global health threats. The results indicated key differences in media narratives between the initial 2011 outbreak and the 2012 postcrisis state. The authors examine the theoretical and practical implications of the findings as well as key limitations and directions for future research.

  12. Vaccinia Virus B1 Kinase Is Required for Postreplicative Stages of the Viral Life Cycle in a BAF-Independent Manner in U2OS Cells

    Science.gov (United States)

    Jamin, Augusta; Ibrahim, Nouhou; Wicklund, April; Weskamp, Kaitlin

    2015-01-01

    ABSTRACT The vaccinia virus B1R gene encodes a highly conserved protein kinase that is essential for the poxviral life cycle. As demonstrated in many cell types, B1 plays a critical role during viral DNA replication when it inactivates the cellular host defense effector barrier to autointegration factor (BAF or BANF1). To better understand the role of B1 during infection, we have characterized the growth of a B1-deficient temperature-sensitive mutant virus (Cts2 virus) in U2OS osteosarcoma cells. In contrast to all other cell lines tested to date, we found that in U2OS cells, Cts2 viral DNA replication is unimpaired at the nonpermissive temperature. However, the Cts2 viral yield in these cells was reduced more than 10-fold, thus indicating that B1 is required at another stage of the vaccinia virus life cycle. Our results further suggest that the host defense function of endogenous BAF may be absent in U2OS cells but can be recovered through either overexpression of BAF or fusion of U2OS cells with mouse cells in which the antiviral function of BAF is active. Interestingly, examination of late viral proteins during Cts2 virus infection demonstrated that B1 is required for optimal processing of the L4 protein. Finally, execution point analyses as well as electron microscopy studies uncovered a role for B1 during maturation of poxviral virions. Overall, this work demonstrates that U2OS cells are a novel model system for studying the cell type-specific regulation of BAF and reveals a role for B1 beyond DNA replication during the late stages of the viral life cycle. IMPORTANCE The most well characterized role for the vaccinia virus B1 kinase is to facilitate viral DNA replication by phosphorylating and inactivating BAF, a cellular host defense responsive to foreign DNA. Additional roles for B1 later in the viral life cycle have been postulated for decades but are difficult to examine directly due to the importance of B1 during DNA replication. Here, we demonstrate that

  13. LIFE-CYCLE ASSESSMENT

    Science.gov (United States)

    Life Cycle Assessment, or LCA, is an environmental accounting and mangement approach that consider all the aspects of resource use and environmental releases associated with an industrial system from cradle-to-grave. Specifically, it is a holistic view of environmental interacti...

  14. Mosquito Life Cycle

    Science.gov (United States)

    Knowing the stages of the mosquito's life will help you prevent mosquitoes around your home and help you choose the right pesticides for your needs, if you decide to use them. All mosquito species go through four distinct stages during their live cycle.

  15. Life Cycle Collection Management

    Directory of Open Access Journals (Sweden)

    Helen Shenton

    2003-09-01

    Full Text Available Life cycle collection management is a way of taking a long-term approach to the responsible stewardship of the British Library's collections and is one of the Library's strategic strands. It defines the different stages in a collection item's existence over time. These stages range from selection and acquisitions processing, cataloguing and press marking, through to preventive conservation, storage and retrieval. Life cycle collection management seeks to identify the costs of each stage in order to show the economic interdependencies between the phases over time. It thereby aims to demonstrate the long-term consequences of what the library takes into its collections, by making explicit the financial and other implications of decisions made at the beginning of the life cycle for the next 100 plus years. This paper describes the work over the past year at the British Library on this complex and complicated subject. It presents the emerging findings and suggests how it can be used for practical reasons (by individual curators and selectors and for economic, governance and political purposes. The paper describes the next steps in the project, for example, on a predictive data model. The British Library is seeking to benchmark itself against comparable organisations in this area. It intends to work with others on specific comparison for example, of life cycle costing of electronic and paper journals, as a prelude to eliding digital and 'traditional' formats.

  16. Life Cycle Sustainability Dashboard

    DEFF Research Database (Denmark)

    Traverso, Marzia; Finkbeiner, Matthias; Jørgensen, Andreas

    2012-01-01

    One method to assess the sustainability performance of products is life cycle sustainability assessment (LCSA), which assesses product performance considering the environmental,economic, and social dimensions of the life cycle. The results of LCSA can be used to compare different products...... or to support decision making toward sustainable production and consumption. In both cases, LCSA results could be too disaggregated and consequently too difficult to understand and interpret by decision makers. As non-experts are usually the target audience of experts and scientists, and are also involved...... in decision-making processes, the necessity for a straightforward but comprehensive presentation of LCSA results is becoming strategically important. The implementation of the dashboard of sustainability proposed in this article offers a possible solution. An outstanding characteristic of the dashboard...

  17. The Pneumocystis life cycle

    Directory of Open Access Journals (Sweden)

    Cécile-Marie Aliouat-Denis

    2009-05-01

    Full Text Available First recognised as "schizonts" of Trypanosoma cruzi, Pneumocystis organisms are now considered as part of an early-diverging lineage of Ascomycetes. As no robust long-term culture model is available, most data on the Pneumocystis cell cycle have stemmed from ultrastructural images of infected mammalian lungs. Although most fungi developing in animals do not complete a sexual cycle in vivo, Pneumocystis species constitute one of a few exceptions. Recently, the molecular identification of several key players in the fungal mating pathway has provided further evidence for the existence of conjugation and meiosis in Pneumocystisorganisms. Dynamic follow-up of stage-to-stage transition as well as studies of stage-specific proteins and/or genes would provide a better understanding of the still hypothetical Pneumocystislife cycle. Although difficult to achieve, stage purification seems a reasonable way forward in the absence of efficient culture systems. This mini-review provides a comprehensive overview of the historical milestones leading to the current knowledge available on the Pneumocystis life cycle.

  18. Life Cycle Inventory Analysis

    DEFF Research Database (Denmark)

    Bjørn, Anders; Moltesen, Andreas; Laurent, Alexis

    2017-01-01

    of different sources. The output is a compiled inventory of elementary flows that is used as basis of the subsequent life cycle impact assessment phase. This chapter teaches how to carry out this task through six steps: (1) identifying processes for the LCI model of the product system; (2) planning......The inventory analysis is the third and often most time-consuming part of an LCA. The analysis is guided by the goal and scope definition, and its core activity is the collection and compilation of data on elementary flows from all processes in the studied product system(s) drawing on a combination...

  19. The software life cycle

    CERN Document Server

    Ince, Darrel

    1990-01-01

    The Software Life Cycle deals with the software lifecycle, that is, what exactly happens when software is developed. Topics covered include aspects of software engineering, structured techniques of software development, and software project management. The use of mathematics to design and develop computer systems is also discussed. This book is comprised of 20 chapters divided into four sections and begins with an overview of software engineering and software development, paying particular attention to the birth of software engineering and the introduction of formal methods of software develop

  20. Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

    Directory of Open Access Journals (Sweden)

    Evelyne Derelle

    Full Text Available Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon.

  1. Life-Cycle and Genome of OtV5, a Large DNA Virus of the Pelagic Marine Unicellular Green Alga Ostreococcus tauri

    Science.gov (United States)

    Derelle, Evelyne; Ferraz, Conchita; Escande, Marie-Line; Eychenié, Sophie; Cooke, Richard; Piganeau, Gwenaël; Desdevises, Yves; Bellec, Laure; Moreau, Hervé; Grimsley, Nigel

    2008-01-01

    Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon. PMID:18509524

  2. LIFE CYCLE OF INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Y. S. Sennik

    2015-01-01

    Full Text Available This work is a generalization of the theoretical propositions related to the life cycle of information systems. There was given the definition of the life cycle, specify which items you should include every step of the cycle. Describes the methodology division of the life cycle on the main stage, including methodology Rational Unified Process. The description of the fundamental standards in this area. Special attention was paid to the work of the basic life cycle models. It was carried out their comparative characteristics. On the basis of the theoretical propositions, it was concluded that the preferred model of the life cycle for the corporate network is a spiral model and the use of international standards in the life cycle saves a lot of effort, time and material resources.

  3. The LifeCycle model

    DEFF Research Database (Denmark)

    Krink, Thiemo; Løvbjerg, Morten

    2002-01-01

    Adaptive search heuristics are known to be valuable in approximating solutions to hard search problems. However, these techniques are problem dependent. Inspired by the idea of life cycle stages found in nature, we introduce a hybrid approach called the LifeCycle model that simultaneously applies...

  4. Emissions from photovoltaic life cycles

    NARCIS (Netherlands)

    Fthenakis, V.M.; Kim, H.C.; Alsema, E.A.|info:eu-repo/dai/nl/073416258

    2008-01-01

    Photovoltaic (PV) technologies have shown remarkable progress recently in terms of annual production capacity and life cycle environmental performances, which necessitate timely updates of environmental indicators. Based on PV production data of 2004–2006, this study presents the life-cycle

  5. Reducing Life-Cycle Costs.

    Science.gov (United States)

    Roodvoets, David L.

    2003-01-01

    Presents factors to consider when determining roofing life-cycle costs, explaining that costs do not tell the whole story; discussing components that should go into the decision (cost, maintenance, energy use, and environmental costs); and concluding that important elements in reducing life-cycle costs include energy savings through increased…

  6. Mutations altering the gammaretrovirus endoproteolytic motif affect glycosylation of the envelope glycoprotein and early events of the virus life cycle

    Energy Technology Data Exchange (ETDEWEB)

    Argaw, Takele; Wilson, Carolyn A., E-mail: carolyn.wilson@fda.hhs.gov

    2015-01-15

    Previously, we found that mutation of glutamine to proline in the endoproteolytic cleavage signal of the PERV-C envelope (RQKK to RPKK) resulted in non-infectious vectors. Here, we show that RPKK results in a non-infectious vector when placed in not only a PERV envelope, but also the envelope of a related gammaretrovirus, FeLV-B. The amino acid substitutions do not prevent envelope precursor cleavage, viral core and genome assembly, or receptor binding. Rather, the mutations result in the formation of hyperglycosylated glycoprotein and a reduction in the reverse transcribed minus strand synthesis and undetectable 2-LTR circular DNA in cells exposed to vectors with these mutated envelopes. Our findings suggest novel functions associated with the cleavage signal sequence that may affect trafficking through the glycosylation machinery of the cell. Further, the glycosylation status of the envelope appears to impact post-binding events of the viral life cycle, either membrane fusion, internalization, or reverse transcription. - Highlights: • Env cleavage signal impacts infectivity of gammaretroviruses. • Non-infectious mutants have hyper-glycosylated envelope that bind target cells. • Non-infectious mutants have defects in the formation of the double-stranded DNA. • Env cleavage motif has functions beyond cleavage of the env precursor.

  7. Life Cycle Costing: An Introduction

    DEFF Research Database (Denmark)

    Rödger, Jan-Markus; Kjær, Louise Laumann; Pagoropoulos, Aris

    2018-01-01

    The chapter gives an introduction to life cycle costing (LCC) and how it can be used to support decision-making. It can form the economic pillar in a full life cycle sustainability assessment, but often system delimitations differ depending on the goal and scope of the study. To provide a profound...... understanding this chapter describes several approaches and terms, fundamental principles and different types of costs. A brief introduction is given to conventional LCC and societal LCC but the main focus is on environmental Life Cycle Costing (eLCC) as the LCC approach that is compatible with environmental...... Life Cycle Assessment (LCA) in terms of system delimitation. Differences are explained and addressed, and an overview is given of the main cost categories to consider from different user perspectives. As inventory data is often sensitive in financial analyses, a list of relevant databases is provided...

  8. Total Product Life Cycle (TPLC)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Total Product Life Cycle (TPLC) database integrates premarket and postmarket data about medical devices. It includes information pulled from CDRH databases...

  9. Towards Life Cycle Sustainability Assessment

    Directory of Open Access Journals (Sweden)

    Marzia Traverso

    2010-10-01

    Full Text Available Sustainability is nowadays accepted by all stakeholders as a guiding principle for both public policy making and corporate strategies. However, the biggest challenge for most organizations remains in the real and substantial implementation of the sustainability concept. The core of the implementation challenge is the question, how sustainability performance can be measured, especially for products and processes. This paper explores the current status of Life Cycle Sustainability Assessment (LCSA for products and processes. For the environmental dimension well established tools like Life Cycle Assessment are available. For the economic and social dimension, there is still need for consistent and robust indicators and methods. In addition to measuring the individual sustainability dimensions, another challenge is a comprehensive, yet understandable presentation of the results. The “Life Cycle Sustainability Dashboard” and the “Life Cycle Sustainability Triangle” are presented as examples for communication tools for both experts and non expert stakeholders.

  10. Equipment life cycle costs minimised.

    Science.gov (United States)

    Kuligowski, Sharon

    2004-11-01

    With the cost of energy now a major component of building operating costs, NHS Trust managers increasingly focus on estimating total life cycle costs of equipment such as boiler room and heat, steam and incineration plant. "Life cycle costing" is a broad term and encompasses a wide range of techniques that take into account both initial and future costs as well as the savings of an investment over a period of time.

  11. The Viral Gene ORF79 Encodes a Repressor Regulating Induction of the Lytic Life Cycle in the Haloalkaliphilic Virus ϕCh1.

    Science.gov (United States)

    Selb, Regina; Derntl, Christian; Klein, Reinhard; Alte, Beatrix; Hofbauer, Christoph; Kaufmann, Martin; Beraha, Judith; Schöner, Léa; Witte, Angela

    2017-05-01

    In this study, we describe the construction of the first genetically modified mutant of a halovirus infecting haloalkaliphilic Archaea By random choice, we targeted ORF79, a currently uncharacterized viral gene of the haloalkaliphilic virus ϕCh1. We used a polyethylene glycol (PEG)-mediated transformation method to deliver a disruption cassette into a lysogenic strain of the haloalkaliphilic archaeon Natrialba magadii bearing ϕCh1 as a provirus. This approach yielded mutant virus particles carrying a disrupted version of ORF79. Disruption of ORF79 did not influence morphology of the mature virions. The mutant virus was able to infect cured strains of N. magadii , resulting in a lysogenic, ORF79-disrupted strain. Analysis of this strain carrying the mutant virus revealed a repressor function of ORF79. In the absence of gp79, onset of lysis and expression of viral proteins occurred prematurely compared to their timing in the wild-type strain. Constitutive expression of ORF79 in a cured strain of N. magadii reduced the plating efficiency of ϕCh1 by seven orders of magnitude. Overexpression of ORF79 in a lysogenic strain of N. magadii resulted in an inhibition of lysis and total absence of viral proteins as well as viral progeny. In further experiments, gp79 directly regulated the expression of the tail fiber protein ORF34 but did not influence the methyltransferase gene ORF94. Further, we describe the establishment of an inducible promoter for in vivo studies in N. magadii IMPORTANCE Genetic analyses of haloalkaliphilic Archaea or haloviruses are only rarely reported. Therefore, only little insight into the in vivo roles of proteins and their functions has been gained so far. We used a reverse genetics approach to identify the function of a yet undescribed gene of ϕCh1. We provide evidence that gp79, a currently unknown protein of ϕCh1, acts as a repressor protein of the viral life cycle, affecting the transition from the lysogenic to the lytic state of the virus

  12. Hepatitis C Virus, Cholesterol and Lipoproteins — Impact for the Viral Life Cycle and Pathogenesis of Liver Disease

    Science.gov (United States)

    Felmlee, Daniel J.; Hafirassou, Mohamed Lamine; Lefevre, Mathieu; Baumert, Thomas F.; Schuster, Catherine

    2013-01-01

    Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates with lipid and lipoprotein metabolism disorders such as hepatic steatosis, hypobetalipoproteinemia, and hypocholesterolemia. Furthermore, virus production is dependent on hepatic very-low-density lipoprotein (VLDL) assembly, and circulating virions are physically associated with lipoproteins in complexes termed lipoviral particles. Evidence has indicated several functional roles for the formation of these complexes, including co-opting of lipoprotein receptors for attachment and entry, concealing epitopes to facilitate immune escape, and hijacking host factors for HCV maturation and secretion. Here, we review the evidence surrounding pathogenesis of the hepatitis C infection regarding lipoprotein engagement, cholesterol and triglyceride regulation, and the molecular mechanisms underlying these effects. PMID:23698400

  13. Antifreeze life cycle assessment (LCA

    Directory of Open Access Journals (Sweden)

    Kesić Jelena

    2005-01-01

    Full Text Available Antifreeze based on ethylene glycol is a commonly used commercial product The classification of ethylene glycol as a toxic material increased the disposal costs for used antifreeze and life cycle assessment became a necessity. Life Cycle Assessment (LCA considers the identification and quantification of raw materials and energy inputs and waste outputs during the whole life cycle of the analyzed product. The objectives of LCA are the evaluation of impacts on the environment and improvements of processes in order to reduce and/or eliminate waste. LCA is conducted through a mathematical model derived from mass and energy balances of all the processes included in the life cycle. In all energy processes the part of energy that can be transformed into some other kind of energy is called exergy. The concept of exergy considers the quality of different types of energy and the quality of different materials. It is also a connection between energy and mass transformations. The whole life cycle can be described by the value of the total loss of exergy. The physical meaning of this value is the loss of material and energy that can be used. The results of LCA are very useful for the analyzed products and processes and for the determined conditions under which the analysis was conducted. The results of this study indicate that recycling is the most satisfactory solution for the treatment of used antifreeze regarding material and energy consumption but the re-use of antifreeze should not be neglected as a solution.

  14. The Sphinx's Riddle: Life and Career Cycles.

    Science.gov (United States)

    Burack, Elmer H.

    1984-01-01

    Career cycles should be considered apart from life cycles, even though the two are interrelated. This essay examines five theories about life and career cycles, and offers insights into their limitations and potential uses. (JB)

  15. The product life cycle revisited

    DEFF Research Database (Denmark)

    Ulhøi, John Parm

    1995-01-01

    Efter et introduktionsafsnit følger afsnit II, hvor der gives en historisk analyse af Life Cycle Assessment (LCA) og Environmental Impact Assessment (EIA). I afsnit III munder analysen ud i en vurdering af ligheder og forskelle mellem LCA analyser og EIA analyser, og en diskussion følger af...

  16. Environmental life-cycle assessment

    Science.gov (United States)

    Kirchain, Randolph E., Jr.; Gregory, Jeremy R.; Olivetti, Elsa A.

    2017-07-01

    Concerns about the planet's health call for a careful evaluation of the environmental impact of materials choices. Life-cycle assessment is a tool that can help identify sustainable materials pathways by considering the burdens of materials both during production and as a product.

  17. Studies on the Life Cycle

    African Journals Online (AJOL)

    Key words:Honeybees, Caste Differentiation, Larval Instar Determination, Life Cycle and Apiculture. ABSTRACT. 103. Ife Journal of Science vol. ... produce honey and beeswax (Seegeren et al., 1996 and Ojeleye, 1999). The dwarf ... Sri Lanka including Philippines and China is Apis. dorsataFabricius (1793) commonly ...

  18. Emissions from photovoltaic life cycles.

    Science.gov (United States)

    Fthenakis, Vasilis M; Kim, Hyung Chul; Alsema, Erik

    2008-03-15

    Photovoltaic (PV) technologies have shown remarkable progress recently in terms of annual production capacity and life cycle environmental performances, which necessitate timely updates of environmental indicators. Based on PV production data of 2004-2006, this study presents the life-cycle greenhouse gas emissions, criteria pollutant emissions, and heavy metal emissions from four types of major commercial PV systems: multicrystalline silicon, monocrystalline silicon, ribbon silicon, and thin-film cadmium telluride. Life-cycle emissions were determined by employing average electricity mixtures in Europe and the United States during the materials and module production for each PV system. Among the current vintage of PV technologies, thin-film cadmium telluride (CdTe) PV emits the least amount of harmful air emissions as it requires the least amount of energy during the module production. However, the differences in the emissions between different PV technologies are very small in comparison to the emissions from conventional energy technologies that PV could displace. As a part of prospective analysis, the effect of PV breeder was investigated. Overall, all PV technologies generate far less life-cycle air emissions per GWh than conventional fossil-fuel-based electricity generation technologies. At least 89% of air emissions associated with electricity generation could be prevented if electricity from photovoltaics displaces electricity from the grid.

  19. Hepatitis B virus DNA integration occurs early in the viral life cycle in anin vitroinfection model via NTCP-dependent uptake of enveloped virus particles.

    Science.gov (United States)

    Tu, Thomas; Budzinska, Magdalena A; Vondran, Florian W R; Shackel, Nicholas A; Urban, Stephan

    2018-02-07

    Chronic infection by the Hepatitis B Virus (HBV) is the major contributor to liver disease worldwide. Though HBV replicates via a nuclear episomal DNA (cccDNA), integration of HBV DNA into the host cell genome is regularly observed in the liver of infected patients. While reported as a pro-oncogenic alteration, the mechanism(s) and timing of HBV DNA integration are not well-understood, chiefly due to the lack of in vitro infection models that have detectable integration events. Here, we have established an in vitro system in which integration can be reliably detected following HBV infection. We measured HBV DNA integration using inverse nested PCR in primary human hepatocytes, HepaRG-NTCP, HepG2-NTCP, and Huh7-NTCP cells after HBV infection. Integration was detected in all cell types at a rate of >1 per 10000 cells, with the most consistent detection in Huh7-NTCP cells. Integration rate remained stable between 3 and 9 days post-infection. HBV DNA integration was efficiently blocked by treatment with 200nM of the HBV entry inhibitor Myrcludex B, but not with 10μM Tenofovir, 100U Interferon alpha, or 1μM of the capsid assembly inhibitor GLS4. This suggests integration of HBV DNA occurs immediately after infection of hepatocytes and is likely independent of de novo HBV replication in this model. Site analysis revealed that HBV DNA integrations were distributed over the entire human genome. Further, integrated HBV DNA sequences were consistent with double-stranded linear HBV DNA being the major precursor. Thus, we have established an in vitro system to interrogate the mechanisms of HBV DNA integration. Importance Hepatitis B Virus (HBV) is a common blood-borne pathogen and, following a chronic infection, can cause liver cancer and liver cirrhosis. Integration of HBV DNA into the host genome occurs in all known members of the hepadnaviridae family, despite this form not being necessary for viral replication. HBV DNA integration has been reported to drive liver cancer

  20. Does It Have a Life Cycle?

    Science.gov (United States)

    Keeley, Page

    2010-01-01

    If life continues from generation to generation, then all plants and animals must go through a life cycle, even though it may be different from organism to organism. Is this what students have "learned," or do they have their own private conceptions about life cycles? The formative assessment probe "Does It Have a Life Cycle?" reveals some…

  1. Novel function of the endoplasmic reticulum degradation-enhancing α-mannosidase-like proteins in the human hepatitis B virus life cycle, mediated by the middle envelope protein.

    Science.gov (United States)

    Lazar, Catalin; Uta, Mihaela; Petrescu, Stefana Maria; Branza-Nichita, Norica

    2017-02-01

    Cells replicating the human hepatitis B virus (HBV) express high levels of degradation-enhancing α-mannosidase-like proteins (EDEMs), a family of proteins involved in the endoplasmic reticulum associated degradation, one of the pathways activated during the unfolded protein response. Owing to their α-1,2 mannosidase activity, the EDEM1-3 proteins are able to process the N-linked glycans of misfolded or incompletely folded proteins, providing the recognition signal for their subsequent degradation. The HBV small (S), medium (M), and large (L) surface proteins bear an N-linked glycosylation site in the common S domain that is partially occupied in all proteins. The M protein contains an additional site in its preS2 domain, which is always functional. Here, we report that these oligosaccharides are processed by EDEMs, more efficiently by EDEM3, which induces degradation of L and S proteins, accompanied by a reduction of subviral particles production. In striking contrast, M not only is spared from degradation but its trafficking is also accelerated leading to an improved secretion. This unusual behavior of the M protein requires strictly the mannose trimming of the preS2 N-linked glycan. Furthermore, we show that HBV secretion is significantly inhibited under strong endoplasmic reticulum stress conditions when M expression is prevented by mutagenesis of the viral genome. These observations unfold unique properties of the M protein in the HBV life cycle during unfolded protein response and point to alternative mechanisms employed by EDEMs to alleviate this stress in case of necessity by promoting glycoprotein trafficking rather than degradation. © 2016 John Wiley & Sons Ltd.

  2. Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus.

    Science.gov (United States)

    Lai, Kang Yiu; Ng, Wing Yiu George; Cheng, Fan Fanny

    2014-01-01

    The recent outbreak of the human Zaire ebolavirus (EBOV) epidemic is spiraling out of control in West Africa. Human EBOV hemorrhagic fever has a case fatality rate of up to 90%. The EBOV is classified as a biosafety level 4 pathogen and is considered a category A agent of bioterrorism by Centers for Disease Control and Prevention, with no approved therapies and vaccines available for its treatment apart from supportive care. Although several promising therapeutic agents and vaccines against EBOV are undergoing the Phase I human trial, the current epidemic might be outpacing the speed at which drugs and vaccines can be produced. Like all viruses, the EBOV largely relies on host cell factors and physiological processes for its entry, replication, and egress. We have reviewed currently available therapeutic agents that have been shown to be effective in suppressing the proliferation of the EBOV in cell cultures or animal studies. Most of the therapeutic agents in this review are directed against non-mutable targets of the host, which is independent of viral mutation. These medications are approved by the Food and Drug Administration (FDA) for the treatment of other diseases. They are available and stockpileable for immediate use. They may also have a complementary role to those therapeutic agents under development that are directed against the mutable targets of the EBOV.

  3. Introducing Life Cycle Impact Assessment

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Huijbregts, Mark AJ

    2015-01-01

    methodology projects and presents the international scientific discussions and methodological consensus attempts in consecutive working groups under the auspices of the Society of Environmental Toxicology and Chemistry (SETAC) as well as the UNEP/ SETAC Life Cycle Initiative, and the (almost) parallel...... standardisation activities under the International Organisation for Standardisation (ISO). A brief introduction is given on the purpose and structure of LCIA. As a common background for the 11 chapters dealing with the characterisation modelling of the most common impact categories, the chapter concludes...

  4. Life cycle assessment : Past, present, and future

    NARCIS (Netherlands)

    Guinée, Jeroen B.; Heijungs, Reinout; Huppes, Gjalt; Zamagni, Alessandra; Masoni, Paolo; Buonamici, Roberto; Ekvall, Tomas; Rydberg, Tomas

    2011-01-01

    Environmental life cycle assessment (LCA) has developed fast over the last three decades. Whereas LCA developed from merely energy analysis to a comprehensive environmental burden analysis in the 1970s, full-fledged life cycle impact assessment and life cycle costing models were introduced in the

  5. Social Life Cycle Assessment Revisited

    Directory of Open Access Journals (Sweden)

    Ruqun Wu

    2014-07-01

    Full Text Available To promote the development of Social Life Cycle Assessment (SLCA, we conducted a comprehensive review of recently developed frameworks, methods, and characterization models for impact assessment for future method developers and SLCA practitioners. Two previous reviews served as our foundations for this review. We updated the review by including a comprehensive list of recently-developed SLCA frameworks, methods and characterization models. While a brief discussion from goal, data, and indicator perspectives is provided in Sections 2 to 4 for different frameworks/methods, the focus of this review is Section 5 where discussion on characterization models for impact assessment of different methods is provided. The characterization models are categorized into two types following the UNEP/SETAC guidelines: type I models without impact pathways and type II models with impact pathways. Different from methods incorporating type I/II characterization models, another LCA modeling approach, Life Cycle Attribute Assessment (LCAA, is also discussed in this review. We concluded that methods incorporating either type I or type II models have limitations. For type I models, the challenge lies in the systematic identification of relevant stakeholders and materiality issues; while for type II models, identification of impact pathways that most closely and accurately represent the real-world causal relationships is the key. LCAA may avoid these problems, but the ultimate questions differ from those asked by the methods using type I and II models.

  6. Technology development life cycle processes.

    Energy Technology Data Exchange (ETDEWEB)

    Beck, David Franklin

    2013-05-01

    This report and set of appendices are a collection of memoranda originally drafted in 2009 for the purpose of providing motivation and the necessary background material to support the definition and integration of engineering and management processes related to technology development. At the time there was interest and support to move from Capability Maturity Model Integration (CMMI) Level One (ad hoc processes) to Level Three. As presented herein, the material begins with a survey of open literature perspectives on technology development life cycles, including published data on %E2%80%9Cwhat went wrong.%E2%80%9D The main thrust of the material presents a rational expose%CC%81 of a structured technology development life cycle that uses the scientific method as a framework, with further rigor added from adapting relevant portions of the systems engineering process. The material concludes with a discussion on the use of multiple measures to assess technology maturity, including consideration of the viewpoint of potential users.

  7. Life Cycle Assessment of Concrete

    Energy Technology Data Exchange (ETDEWEB)

    Sjunnesson, Jeannette

    2005-09-15

    This is an environmental study on concrete that follows the standard protocol of life cycle assessment (LCA). The study is done for two types of concrete, ordinary and frost-resistant concrete, and has an extra focus on the superplasticizers used as admixtures. The utilization phase is not included in this study since the type of construction for which the concrete is used is not defined and the concrete is assumed to be inert during this phase. The results show that it is the production of the raw material and the transports involved in the life cycle of concrete that are the main contributors to the total environmental load. The one single step in the raw material production that has the highest impact is the production of cement. Within the transportation operations the transportation of concrete is the largest contributor, followed by the transportation of the cement. The environmental impact of frost-resistant concrete is between 24-41 % higher than that of ordinary concrete due to its higher content of cement. Superplasticizers contribute with approximately 0.4-10.4 % of the total environmental impact of concrete, the least to the global warming potential (GWP) and the most to the photochemical ozone creation potential (POCP). Also the toxicity of the superplasticizers is investigated and the conclusion is that the low amount of leakage of superplasticizers from concrete leads to a low risk for the environment and for humans.

  8. Life cycle of transformer oil

    Directory of Open Access Journals (Sweden)

    Đurđević Ksenija R.

    2008-01-01

    Full Text Available The consumption of electric power is constantly increasing due to industrialization and population growth. This results in much more severe operating conditions of transformers, the most important electrical devices that make integral parts of power transmission and distribution systems. The designed operating life of the majority of worldwide transformers has already expired, which puts the increase of transformer reliability and operating life extension in the spotlight. Transformer oil plays a very important role in transformer operation, since it provides insulation and cooling, helps extinguishing sparks and dissolves gases formed during oil degradation. In addition to this, it also dissolves moisture and gases from cellulose insulation and atmosphere it is exposed to. Further and by no means less important functions of transformer are of diagnostic purpose. It has been determined that examination and inspection of insulation oil provide 70% of information on transformer condition, which can be divided in three main groups: dielectric condition, aged transformer condition and oil degradation condition. By inspecting and examining the application oil it is possible to determine the condition of insulation, oil and solid insulation (paper, as well as irregularities in transformer operation. All of the above-mentioned reasons and facts create ground for the subject of this research covering two stages of transformer oil life cycle: (1 proactive maintenance and monitoring of transformer oils in the course of utilization with reference to influence of transformer oil condition on paper insulation condition, as well as the condition of the transformer itself; (2 regeneration of transformer oils for the purpose of extension of utilization period and paper insulation revitalization potential by means of oil purification. The study highlights advantages of oil-paper insulation revitalization over oil replacement. Besides economic, there are

  9. Life cycle of phytoreoviruses visualized by electron microscopy and tomography

    Directory of Open Access Journals (Sweden)

    Naoyuki eMiyazaki

    2013-10-01

    Full Text Available Rice dwarf virus (RDV and Rice gall dwarf virus (RGDV, members of the genus Phytoreovirus in the family Reoviridae, are known as agents of rice disease, because their spread results in substantial economic damage in many Asian countries. These viruses are transmitted via insect vectors, and they multiply both in the plants and in the insect vectors. Structural information about the viruses and their interactions with cellular components in the life cycle are essential for understanding viral infection and replication mechanisms. The life cycle of the viruses involves various cellular events such as cell entry, synthesis of viral genome and proteins, assembly of viral components, viral egress from infected cells, and intra- and inter-cellular transports. This review focuses on the major events underlying the life cycle of phytoreoviruses, which has been visualized by various EM imaging techniques, including cryo-electron microscopy and tomography, and demonstrates the advantage of the advanced EM imaging techniques to investigate the viral infection and replication mechanisms.

  10. An integrated life cycle inventory for demolition processes in the context of life cycle sustainability assessment

    DEFF Research Database (Denmark)

    Bozhilova-Kisheva, Kossara Petrova; Hu, Mingming; van Roekel, Eric

    2012-01-01

    According to the Life Cycle Assessment in Building and Construction: State-of-the-Art Report (2003), the dismantling and demolition stage of the building life cycle is only sometimes included in the Life Cycle Inventory (LCI) when doing Life Cycle Assessments (LCA). The reason that it is less...... inventoried in a traditional LCA maybe because this stage is expected to have a negligible environmental impact comparing to other stages in the life cycle of the buildings. When doing a life cycle sustainability assessment considering not only environmental but also economic and social impacts, the impacts...

  11. Transportation life cycle assessment (LCA) synthesis : life cycle assessment learning module series.

    Science.gov (United States)

    2015-03-12

    The Life Cycle Assessment Learning Module Series is a set of narrated, self-advancing slideshows on : various topics related to environmental life cycle assessment (LCA). This research project produced the first 27 of such modules, which : are freely...

  12. Life cycle assessment of greenhouse gas emissions

    NARCIS (Netherlands)

    Reijnders, L.; Chen, W.Y.; Seiner, J.; Suzuki, T.; Lackner, M.

    2012-01-01

    Life cycle assessments of greenhouse gas emissions have been developed for analyzing products "from cradle to grave": from resource extraction to waste disposal. Life cycle assessment methodology has also been applied to economies, trade between countries, aspects of production and to waste

  13. Social Life Cycle Assessment: An Introduction

    DEFF Research Database (Denmark)

    Moltesen, Andreas; Bonou, Alexandra; Wangel, Arne

    2017-01-01

    An expansion of the LCA framework has been going on through the development of ‘social life cycle assessment’—S-LCA. The methodology, still in its infancy, has the goal of assessing social impacts related to a product’s life cycle. This chapter introduces S-LCA framework area and the related...

  14. Effective risk management SOGO life cycle management

    OpenAIRE

    Ali, Mohamed Omar

    2012-01-01

    Master's thesis in Industrial Economics After new or upgrade projects the offshore installation gets maintenance or support through the life cycle management organization at Siemens. Small to medium modification projects are executed by the life cycle management. Risk assessment on these projects show different risks when it comes to estimation and pricing of projects, planning and executing, resource management, competence and knowledge.

  15. Effective risk management SOGO life cycle management

    OpenAIRE

    Ali, Mohamed Omar

    2012-01-01

    After new or upgrade projects the offshore installation gets maintenance or support through the life cycle management organization at Siemens. Small to medium modification projects are executed by the life cycle management. Risk assessment on these projects show different risks when it comes to estimation and pricing of projects, planning and executing, resource management, competence and knowledge.

  16. Life Cycle Assessment of Greenhouse Gas Emissions

    NARCIS (Netherlands)

    Reijnders, L.; Chen, W.Y.; Suzuki, T.; Lackner, M.

    2016-01-01

    Life cycle assessments of greenhouse gas emissions have been developed for analyzing products "from cradle to grave": from resource extraction to waste disposal. Life cycle assessment methodology has also been applied to economies, trade between countries, aspects of production, and waste

  17. Social Life Cycle Assessment: An Introduction

    DEFF Research Database (Denmark)

    Moltesen, Andreas; Bonou, Alexandra; Wangel, Arne

    2017-01-01

    An expansion of the LCA framework has been going on through the development of ‘social life cycle assessment’—S-LCA. The methodology, still in its infancy, has the goal of assessing social impacts related to a product’s life cycle. This chapter introduces S-LCA framework area and the related chal...

  18. From life cycle talking to taking action

    NARCIS (Netherlands)

    Potting, J.; Curran, M.A.; Blottnitz, von H.

    2010-01-01

    Introduction - The biannual Life Cycle Management conference series aims to create a platform for users and developers of Life Cycle Assessment (LCA) and related tools to share their experiences. A key concern of the LCM community has been to move beyond the production of LCA reports toward using

  19. Life-cycle assessment of semiconductors

    CERN Document Server

    Boyd, Sarah B

    2012-01-01

    Life-Cycle Assessment of Semiconductors presents the first and thus far only available transparent and complete life cycle assessment of semiconductor devices. A lack of reliable semiconductor LCA data has been a major challenge to evaluation of the potential environmental benefits of information technologies (IT). The analysis and results presented in this book will allow a higher degree of confidence and certainty in decisions concerning the use of IT in efforts to reduce climate change and other environmental effects. Coverage includes but is not limited to semiconductor manufacturing trends by product type and geography, unique coverage of life-cycle assessment, with a focus on uncertainty and sensitivity analysis of energy and global warming missions for CMOS logic devices, life cycle assessment of flash memory and life cycle assessment of DRAM. The information and conclusions discussed here will be highly relevant and useful to individuals and institutions. The book also: Provides a detailed, complete a...

  20. Life Cycle. K-6 Science Curriculum.

    Science.gov (United States)

    Blueford, J. R.; And Others

    Life Cycle is one of the units of a K-6 unified science curriculum program. The unit consists of four organizing sub-themes: (1) past life (focusing on dinosaurs and fossil formation, types, and importance); (2) animal life (examining groups of invertebrates and vertebrates, cells, reproduction, and classification systems); (3) plant life…

  1. Phage Life Cycles Behind Bacterial Biodiversity.

    Science.gov (United States)

    Olszak, Tomasz; Latka, Agnieszka; Roszniowski, Bartosz; Valvano, Miguel A; Drulis-Kawa, Zuzanna

    2017-11-24

    Bacteriophages (phages or bacterial viruses) are the most abundant biological entities in our planet; their influence reaches far beyond the microorganisms they parasitize. Phages are present in every environment and shape up every bacterial population in both active and passive ways. They participate in the circulation of organic matter and drive the evolution of microorganisms by horizontal gene transfer at unprecedented scales. The mass flow of genetic information in the microbial world influences the biosphere and poses challenges for science and medicine. The genetic flow, however, depends on the fate of the viral DNA injected into the bacterial cell. The archetypal notion of phages only engaging in predatorprey relationships is slowly fading. Because of their varied development cycles, environmental conditions, and the diversity of microorganisms they parasitize, phages form a dense and highly complex web of dependencies, which has important consequences for life on Earth. The sophisticated phage-bacteria interplay includes both aggressive action (bacterial lysis) and "diplomatic negotiations" (prophage domestication). Here, we review the most important mechanisms of interactions between phages and bacteria and their evolutionary consequences influencing their biodiversity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  2. Recent developments in Life Cycle Assessment

    DEFF Research Database (Denmark)

    Finnveden, Göran; Hauschild, Michael Zwicky; Ekvall, Tomas

    2009-01-01

    Life Cycle Assessment is a tool to assess the environmental impacts and resources used throughout a product’s life cycle, i.e., from raw material acquisition, via production and use phases, to waste management. The methodological development in LCA has been strong, and LCA is broadly applied...... on Life Cycle Impact Assessment we discuss the characteristics of the modelling as well as some recent developments for specific impact categories and weighting. In relation to the Interpretation the focus is on uncertainty analysis. Finally, we discuss recent developments in relation to some...

  3. Life cycle of transformer oil

    OpenAIRE

    Đurđević Ksenija R.; Vojinović-Miloradov Mirjana; Sokolović Slobodan M.

    2008-01-01

    The consumption of electric power is constantly increasing due to industrialization and population growth. This results in much more severe operating conditions of transformers, the most important electrical devices that make integral parts of power transmission and distribution systems. The designed operating life of the majority of worldwide transformers has already expired, which puts the increase of transformer reliability and operating life extension in the spotlight. Transformer oil pla...

  4. Life cycle assessment of asphalt pavement maintenance.

    Science.gov (United States)

    2014-01-01

    This study aims at developing a life cycle assessment (LCA) model to quantify the impact of pavement preservation on energy consumption and greenhouse gas (GHG) emissions. The construction stage contains material, manufacture, transportation and plac...

  5. Life-cycle assessment of Nebraska bridges.

    Science.gov (United States)

    2013-05-01

    Life-cycle cost analysis (LCCA) is a necessary component in bridge management systems (BMSs) for : assessing investment decisions and identifying the most cost-effective improvement alternatives. The : LCCA helps to identify the lowest cost alternati...

  6. Life cycle costs for Alaska bridges.

    Science.gov (United States)

    2014-08-01

    A study was implemented to assist the Alaska Department of Transportation and Public Facilities (ADOT&PF) with life cycle costs for : the Alaska Highway Bridge Inventory. The study consisted of two parts. Part 1 involved working with regional offices...

  7. Life-cycle costing: Practical considerations

    Science.gov (United States)

    Eisenberger, I.; Lorden, G.

    1977-01-01

    The history and methodology of life-cycle costing are presented and analyzed, contrasting the potential benefits of the technique with the difficulties of its application. Examples and a short survey of the literature are given.

  8. Simplified Life-Cycle Cost Estimation

    Science.gov (United States)

    Remer, D. S.; Lorden, G.; Eisenberger, I.

    1983-01-01

    Simple method for life-cycle cost (LCC) estimation avoids pitfalls inherent in formulations requiring separate estimates of inflation and interest rates. Method depends for validity observation that interest and inflation rates closely track each other.

  9. Towards Quantitative Factory Life Cycle Evaluation

    OpenAIRE

    Nielsen, Lars; Schmidt, Christopher; Blume, Stefan; Schmidt, Matthias; Thiede, Sebastian; Nyhuis, Peter; Herrmann, Christoph

    2016-01-01

    Manufacturing companies face the challenge of understanding and improving complex factory systems in order to stay competitive in a turbulent environment. Interrelated and overlapping life cycles of products and physical factory elements (e.g. machine tools, technical building services, building shell) are challenges to be handled in factory planning and operation. This work discusses both qualitative and quantitative factory life cycle models, analyzing addressed sustainability goals. Due to...

  10. Fuel cell hybrid taxi life cycle analysis

    Energy Technology Data Exchange (ETDEWEB)

    Baptista, Patricia, E-mail: patricia.baptista@ist.utl.pt [IDMEC-Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1, 1049-001 Lisboa (Portugal); Ribau, Joao; Bravo, Joao; Silva, Carla [IDMEC-Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1, 1049-001 Lisboa (Portugal); Adcock, Paul; Kells, Ashley [Intelligent Energy, Charnwood Building, HolywellPark, Ashby Road, Loughborough, LE11 3GR (United Kingdom)

    2011-09-15

    A small fleet of classic London Taxis (Black cabs) equipped with hydrogen fuel cell power systems is being prepared for demonstration during the 2012 London Olympics. This paper presents a Life Cycle Analysis for these vehicles in terms of energy consumption and CO{sub 2} emissions, focusing on the impacts of alternative vehicle technologies for the Taxi, combining the fuel life cycle (Tank-to-Wheel and Well-to-Tank) and vehicle materials Cradle-to-Grave. An internal combustion engine diesel taxi was used as the reference vehicle for the currently available technology. This is compared to battery and fuel cell vehicle configurations. Accordingly, the following energy pathways are compared: diesel, electricity and hydrogen (derived from natural gas steam reforming). Full Life Cycle Analysis, using the PCO-CENEX drive cycle, (derived from actual London Taxi drive cycles) shows that the fuel cell powered vehicle configurations have lower energy consumption (4.34 MJ/km) and CO{sub 2} emissions (235 g/km) than both the ICE Diesel (9.54 MJ/km and 738 g/km) and the battery electric vehicle (5.81 MJ/km and 269 g/km). - Highlights: > A Life Cycle Analysis of alternative vehicle technologies for the London Taxi was performed. > The hydrogen powered vehicles have the lowest energy consumption and CO{sub 2} emissions results. > A hydrogen powered solution can be a sustainable alternative in a full life cycle framework.

  11. A case study by life cycle assessment

    Science.gov (United States)

    Li, Shuyun

    2017-05-01

    This article aims to assess the potential environmental impact of an electrical grinder during its life cycle. The Life Cycle Inventory Analysis was conducted based on the Simplified Life Cycle Assessment (SLCA) Drivers that calculated from the Valuation of Social Cost and Simplified Life Cycle Assessment Model (VSSM). The detailed results for LCI can be found under Appendix II. The Life Cycle Impact Assessment was performed based on Eco-indicator 99 method. The analysis results indicated that the major contributor to the environmental impact as it accounts for over 60% overall SLCA output. In which, 60% of the emission resulted from the logistic required for the maintenance activities. This was measured by conducting the hotspot analysis. After performing sensitivity analysis, it is evidenced that changing fuel type results in significant decrease environmental footprint. The environmental benefit can also be seen from the negative output values of the recycling activities. By conducting Life Cycle Assessment analysis, the potential environmental impact of the electrical grinder was investigated.

  12. Ocean viruses and their effects on microbial communities and biogeochemical cycles.

    Science.gov (United States)

    Weitz, Joshua S; Wilhelm, Steven W

    2012-01-01

    Viruses are the most abundant life forms on Earth, with an estimated 10(31) total viruses globally. The majority of these viruses infect microbes, whether bacteria, archaea or microeukaryotes. Given the importance of microbes in driving global biogeochemical cycles, it would seem, based on numerical abundances alone, that viruses also play an important role in the global cycling of carbon and nutrients. However, the importance of viruses in controlling host populations and ecosystem functions, such as the regeneration, storage and export of carbon and other nutrients, remains unresolved. Here, we report on advances in the study of ecological effects of viruses of microbes. In doing so, we focus on an area of increasing importance: the role that ocean viruses play in shaping microbial population sizes as well as in regenerating carbon and other nutrients.

  13. Life Cycle Cost Analysis Handbook. First Edition.

    Science.gov (United States)

    Alaska State Dept. of Education and Early Development, Juneau.

    This handbook presents guidelines on the Life Cycle Cost Analysis (LCCA) of building operations over the life of a building to assist school districts and consultants with evaluating proposed educational facility construction projects. It defines the terminology found in an LCCA, such as initial and future expenses, residual value, real discount…

  14. Life Cycle Assessment and Risk Assessment

    DEFF Research Database (Denmark)

    Olsen, Stig Irving

    Life Cycle Assessment (LCA) is a tool for environmental assessment of product and systems – over the whole life cycle from acquisition of raw materials to the end-of-life of the product – and encompassing all environmental impacts of emissions and resource usage, e.g. global warming, acidification...... and toxicity. Whereas Risk Assessment (RA) aims to identify absolute risks, LCA assess potential or relative impacts. LCA is readily applicable to nanotechnologies and several studies have been carried out, but LCA faces large problems when addressing toxic impacts of nanomaterials emitted during the life...... cycle. The models for assessing toxic impacts in LCA are to a large extent based on those developed for RA, e.g. EUSES, and require basic information about the inherent properties of the emissions like solubility, LogKow,ED50 etc. Additionally, it is a prerequisite to know how to characterize...

  15. Optimal Life Cycle Portfolio Choice with Housing Market Cycles

    DEFF Research Database (Denmark)

    Fischer, Marcel; Stamos, Michael Z.

    2013-01-01

    In recent decades U.S. households have experienced residential house prices moving persistently, that is, returns being positively serially correlated. We set up a realistically calibrated life cycle model with slow-moving time variation in expected housing returns, showing that not only age, labor...... income, and pre-existing housing wealth but also the state of the housing market significantly affect household decisions. Consistently with the data, the model predicts that in good states of housing market cycles (1) homeownership rates increase, (2) households buying homes invest a larger share...

  16. Implementing Life Cycle Assessment in Product development

    DEFF Research Database (Denmark)

    Bhander, Gurbakhash Singh

    2003-01-01

    The overall aim of the paper is to provide an understanding of the environmental issues involved in the early stages of product development and the capacity of life cycle assessment techniques to address these issues. The paper aims to outline the problems for the designer in evaluating......, and of the opportunities for introducing environmental criteria in the design process through meeting the information requirements of the designer on the different life cycle stages, producing an in-depth understanding of the attitudes of practitioners among product developers to the subject area, and an understanding...... of possible future directions for product development. An Environmentally Conscious Design method is introduced and trade-offs are presented between design degrees of freedom and environmental solutions. Life cycle design frameworks and strategies are addressed. The paper collects experiences and ideas around...

  17. Implementing Life Cycle Assessment in systems development

    DEFF Research Database (Denmark)

    Bhander, Gurbakhash Singh; Hauschild, Michael Zwicky; McAloone, Timothy Charles

    2003-01-01

    Today's industry is being forced to consider the environmental performance of its products concurrently with traditional requirements such as quality, price or functional performance. The Life Cycle Assessment (LCA) technique has been identified as a powerful tool to calculate environmental impacts...... and the rapid changes in markets for many products. The overall aim of the paper is to provide an understanding of the environmental issues involved in the early stages of product development and the capacity of life cycle assessment techniques to address these issues. The paper aims to outline the problems...... of the barriers to implementation of LCA by developers of products, and of the opportunities for introducing environmental criteria in the design process through meeting the information requirements of the designer on the different life cycle stages, producing an in-depth understanding of the attitudes...

  18. Life Cycle assessment of basic chemicals

    DEFF Research Database (Denmark)

    Olsen, Stig Irving

    chemicals. A survey of the use of LCA in the European chemical industry has been conducted and is reported in appendix 1. Life cycle assessment (LCA) is a tool/process to evaluate the potential environmental impacts of a system (most often a product) through its whole life cycle by collecting input......The present report results as part of a ph.d. project aiming at developing general rules for LCA of basic chemicals. Part 1 reviews the state of the art framework for life-cycle assessment and part 2 relates that framework to the chemical industry and gives some proposals for LCAs of basic...... provided a good, although at times somewhat conservative estimate of the emissions. A special problem occurs when there are two or more product produced in the same process, a situation frequently encountered in chemical manufacturing. In such cases the environmental interventions of the process have...

  19. Comparative myoanatomy of cycliophoran life cycle stages

    DEFF Research Database (Denmark)

    Neves, Ricardo C.; Cunha, Maria R.; Funch, Peter

    2010-01-01

    The metazoan phylum Cycliophora includes small cryptic epibionts that live attached to the mouthparts of clawed lobsters. The life cycle is complex, with alternating sexual and asexual generations, and involves several sessile and free-living stages. So far, the morphological and genetic...... on the dorsal side, whereas on the ventral side, longitudinal muscles and a V-shaped muscle structure are present. These muscles are complemented by additional dorsoventral muscles. The mesodermal muscle fibers attach to the cuticle via the epidermis in all life cycle stages studied herein. The musculature...... of the female is similar to that of the Pandora larva of Symbion americanus and includes dorsoventral muscles and longitudinal muscles that run in the dorsal and ventral body region. Overall, our results reveal striking similarities in the muscular arrangement of the life cycle stages of both Symbion species. J...

  20. Weapons barrel life cycle determination

    Directory of Open Access Journals (Sweden)

    Nebojša Pene Hristov

    2013-10-01

    Full Text Available This article describes the dynamic processes within the gun barrel during the firing process in exploitation. It generally defines the basic principles of constructing tube elements, and shows the distortion of the basic geometry of the tube interior due to wear as well as the impact it causes during exploitation. The article also defines basic empirical models as well as a model based on fracture mechanics for the calculation of a use-life of the barrel, and other elements essential for the safe use of the barrel as the basic weapon element. Erosion causes are analysed in order to control and reduce wear and prolong the lifetime of the gun barrel. It gives directions for the reparation of barrels with wasted resources. In conclusion, the most influential elements of tube wear are given as well as possible modifications of existing systems, primarily propellant charges, with a purpose of prolonging lifetime of gun barrels. The guidelines for a proper determination of the lifetime based on the barrel condition assessment are given as well. INTRODUCTION The barrel as the basic element of each weapon is described as well as the processes occurring during the firing that have impulsive character and are accompanied by large amounts of energy. The basic elements of barrel and itheir constructive characteristics are descibed. The relation between Internal ballistics, ie calculation of the propellant gas pressure in the firing process, and structural elements defined by the barrel material resistance is shown. In general, this part of the study explains the methodology of the gun barrel structural elements calculation, ie. barrel geometry, taking into account the degrees of safety in accordance with Military Standards.   TUBE WEAR AND DEFORMATIONS The weapon barrel gradually wears out during exploitation due to which it no longer satisfies the set requirements. It is considered that the barrel has experienced a lifetime when it fails to fulfill the

  1. Comparing the Life Cycle Energy Consumption, Global ...

    Science.gov (United States)

    Managing the water-energy-nutrient nexus for the built environment requires, in part, a full system analysis of energy consumption, global warming and eutrophication potentials of municipal water services. As an example, we evaluated the life cycle energy use, greenhouse gas (GHG) emissions and aqueous nutrient releases of the whole anthropogenic municipal water cycle starting from raw water extraction to wastewater treatment and reuse/discharge for five municipal water and wastewater systems. The assessed options included conventional centralized services and four alternative options following the principles of source-separation and water fit-for-purpose. The comparative life cycle assessment identified that centralized drinking water supply coupled with blackwater energy recovery and on-site greywater treatment and reuse was the most energyand carbon-efficient water service system evaluated, while the conventional (drinking water and sewerage) centralized system ranked as the most energy- and carbon-intensive system. The electricity generated from blackwater and food residuals co-digestion was estimated to offset at least 40% of life cycle energy consumption for water/waste services. The dry composting toilet option demonstrated the lowest life cycle eutrophication potential. The nutrients in wastewater effluent are the dominating contributors for the eutrophication potential for the assessed system configurations. Among the parameters for which variability

  2. Life-cycle cost analysis of adsorption cycles for desalination

    KAUST Repository

    Thu, Kyaw

    2010-08-01

    This paper presents the thermo-economic analysis of the adsorption desalination (AD) cycle that is driven by low-temperature waste heat from exhaust of industrial processes or renewable sources. The AD cycle uses an adsorbent such as the silica gel to desalt the sea or brackish water. Based on an experimental prototype AD plant, the life-cycle cost analysis of AD plants of assorted water production capacities has been simulated and these predictions are translated into unit cost of water production. Our results show that the specific energy consumption of the AD cycle is 1.38 kWh/m3 which is the lowest ever reported. For a plant capacity of 1000 m3/d, the AD cycle offers a unit cost of $0.457/m3 as compared to more than $0.9 for the average RO plants. Besides being cost-effective, the AD cycle is also environment-friendly as it emits less CO2 emission per m3 generated, typically 85% less, by comparison to an RO process. © 2010 Desalination Publications.

  3. An Integrated Framework for Life Cycle Engineering

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Herrmann, Christoph; Kara, Sami

    2017-01-01

    has broadened, and as a result, LCE has evolved in parallel with other disciplines with similar aims. Currently, in addition to LCE, there exist a number of concepts such as Industrial Ecology, Cleaner Production, Life Cycle Management (LCM), Industrial Symbiosis, and Circular Economy. As a result......Life Cycle Engineering (LCE) was introduced as a concept more than 24 years ago in order to address emerging concerns about environmental sustainability in engineering. A number of methods and tools have been introduced to operationalise the LCE concept, but since then, the scope of sustainability...

  4. LIFE CYCLE OF A WINE BRAND

    Directory of Open Access Journals (Sweden)

    Viktoriia Paziuk

    2015-11-01

    Full Text Available The aim of the work is to determine the life cycle of the wine brand, the development of ways to improve its effectiveness at different stages of the life cycle. Being scientifically informed of the existence of the life cycle of the brand allows modern enterprises to enhance their competitive position in the market and take advantage of the acquired differences in order to attract more attention from consumers. Methods. The study is based on scientific methods of research of economic phenomena: the dialectic, abstract logical (in the exercise of theoretical generalizations to the definition of the concept of «life cycle of the perpetrator of the brand, a scientific abstraction, comparison and ordering (the study of factors influencing the life cycle of the perpetrator of the brand and the factors influencing a choice of products for consumers, statistical and problem-chronological (the study of the requirements of the brand in a changing consumer preferences, logical generalization (in determining the social and ethical functions guilty brand. Results. The stages of the life cycle of the wine brand, which take into account its characteristics and form its social and ethical functions. Describing the requirements for the wine brand in the changing tastes and preferences of consumers. Specification of wine promotion of the brand in an increasingly competitive environment. Preconditions have been set for a new wine brand. The practical significance. The brand always increases the value of the product and its entry into new markets, as well as reduces the time to attract consumers. Possibility to ensure the growth of the brand in a declining market; building market share in a highly competitive environment; marketing innovative products in order to create a new sales strategy. After all, to gain and maintain the popularity of a certain product, one must personalize it with giving associations and a way to provide it with distinctive features. Only

  5. Life cycle assessment of renewable energy sources

    CERN Document Server

    Singh, Anoop; Olsen, Stig Irving

    2013-01-01

    Governments are setting challenging targets to increase the production of energy and transport fuel from sustainable sources. The emphasis is increasingly on renewable sources including wind, solar, geothermal, biomass based biofuel, photovoltaics or energy recovery from waste. What are the environmental consequences of adopting these other sources? How do these various sources compare to each other? Life Cycle Assessment of Renewable Energy Sources tries to answer these questions based on the universally adopted method of Life Cycle Assessment (LCA). This book introduces the concept and impor

  6. Life-Cycle Cost-Benefit Analysis

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    2010-01-01

    The future use of Life-Cycle Cost-Benefit (LCCB) analysis is discussed in this paper. A more complete analysis including not only the traditional factors and user costs, but also factors which are difficult to include in the analysis is needed in the future.......The future use of Life-Cycle Cost-Benefit (LCCB) analysis is discussed in this paper. A more complete analysis including not only the traditional factors and user costs, but also factors which are difficult to include in the analysis is needed in the future....

  7. Life Cycle Assessment of Slurry Management Technologies

    DEFF Research Database (Denmark)

    Wesnæs, Marianne; Wenzel, Henrik; Petersen, Bjørn Molt

    Cycle perspective. Through this the companies can evaluate the environmental benefits and disadvantages of introducing a specific technology for slurry management. From a societal perspective the results can contribute to a clarification of which slurry management technologies (or combination......This report contains the results of Life Cycle Assessments of two slurry management technologies - acidification and decentred incineration. The LCA foundation can be used by the contributing companies for evaluating the environmental sustainability of a specific technology from a holistic Life...... of technologies) having the largest potential for reducing the overall environmental impacts....

  8. 10 CFR 436.12 - Life cycle cost methodology.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Life cycle cost methodology. 436.12 Section 436.12 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION FEDERAL ENERGY MANAGEMENT AND PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.12 Life cycle cost methodology. The life cycle cost methodology...

  9. Product Life Cycle - Quality Management Issues

    DEFF Research Database (Denmark)

    Alting, Leo; Majstorovic, Vidosav D.

    2004-01-01

    The strategic goal of our country is European and world integration. Within this context the management of sustainable development considered from the aspect of product’s life cycle and its quality management represents a real challenge for researchers, economy and educational system. The aim...

  10. Monetary valuation in Life Cycle Assessment

    DEFF Research Database (Denmark)

    Pizzol, Massimo; Weidema, Bo Pedersen; Brandão, Miguel

    2015-01-01

    different impacts and/or with other economic costs and benefits. For this reason, monetary valuation has a great potential to be applied also in Life Cycle Assessment (LCA), especially in the weighting phase. However, several challenges limit its diffusion in the field, which resulted in only a few...

  11. Sensitivity analysis in life cycle assessment

    NARCIS (Netherlands)

    Groen, E.A.; Heijungs, R.; Bokkers, E.A.M.; Boer, de I.J.M.

    2014-01-01

    Life cycle assessments require many input parameters and many of these parameters are uncertain; therefore, a sensitivity analysis is an essential part of the final interpretation. The aim of this study is to compare seven sensitivity methods applied to three types of case stud-ies. Two

  12. Asset Allocation Over the Life Cycle

    DEFF Research Database (Denmark)

    Fischer, Marcel; Kraft, Holger; Munk, Claus

    2013-01-01

    We study the welfare effect of tax-optimizing portfolio decisions in a life cycle model with unspanned labor income and realization-based capital gain taxation. For realistic parameterizations of our model, certainty equivalent welfare gains from fully tax-optimized portfolio decisions are less...

  13. Developing IAM for Life Cycle Safety Assessment

    NARCIS (Netherlands)

    Toxopeus, Marten E.; Lutters, Diederick; Nee, Andrew Y.C.; Song, Bin; Ong, Soh-Khim

    2013-01-01

    This publication discusses aspects of the development of an impact assessment method (IAM) for safety. Compared to the many existing IAM’s for environmentally oriented LCA, this method should translate the impact of a product life cycle on the subject of safety. Moreover, the method should be

  14. Emerald ash borer life cycle: a reassessment

    Science.gov (United States)

    David Cappaert; Deborah McCullough; Therese Poland

    2005-01-01

    To establish the life cycle of EAB was one of the first objectives of EAB research. Our expectation was that Agrilus planipennis phenology would coincide roughly with that of well-characterized Agrilus species such as A. anxius and A. bilineatus: 1) mid-summer adult flight and oviposition; 2)...

  15. Training Groups: A Basic Life Cycle Model.

    Science.gov (United States)

    Chadbourne, Joan

    1980-01-01

    Describes group training model that differs from the traditional T-group model in structure, leadership, and assumptions about learning. The life-cycle model is based on situational leadership, differential structures based on group maturity, and integration of conceptual and experiential learning. (Author)

  16. The life cycle of social media

    OpenAIRE

    Franses, Philip Hans

    2014-01-01

    markdownabstract__Abstract__ Using weekly data on the interest for 17 social media via Google trends and using quarterly data on actual users for 3 social media, it is reported in this letter that the life cycles of social media mimic those of durable consumer goods. On average, the popularity of social media peaks after 4 years since entry.

  17. Semantic catalogs for life cycle assessment data

    NARCIS (Netherlands)

    Kuczenski, Brandon; Davis, Christopher B.; Rivela, Beatriz; Janowicz, Krzysztof

    2016-01-01

    Life cycle assessment (LCA) is a highly interdisciplinary field that requires knowledge from different domains to be gathered and interpreted together. Although there are relatively few major data sources for LCA, the data themselves are presented with highly heterogeneous formats, interfaces, and

  18. A model for life cycle records management

    Energy Technology Data Exchange (ETDEWEB)

    Tayfun, A.C.; Gibson, S.

    1996-10-01

    The primary objective of this paper is to update an old Records Management concept; the management of records according to the records life cycle. Accordingly, the authors are presenting a new version of the Records Management life cycle model and its associated elements. The basic concept is that every record progresses through three phases; a record is created, is used and maintained, and dispositioned. In this presentation, the authors update the very old straight line model and the more current circular model with a new model that essentially combines the two. The model portrays Records Management as having a distinct straight-line beginning, a circular use and maintenance phase, and a distinct straight-line end. The presentation maps Records Management Program elements and activities against the phases depicted in the model. The authors believe that this new records life cycle model is an enhanced physical representation of the process. This presentation is designed to help put all of the specialized Records Management topics that participants have heard about during the conference in the perspective of the records life cycle.

  19. Predictors and Portfolios Over the Life Cycle

    DEFF Research Database (Denmark)

    Kraft, Holger; Munk, Claus; Weiss, Farina

    In a calibrated consumption-portfolio model with stock, housing, and labor income predictability, we evaluate the welfare effects of predictability on life-cycle consumption-portfolio choice. We compare skilled investors who are able to take advantage of all sources of predictability with unskilled...

  20. Maintenance: Changing Role in Life Cycle Management

    NARCIS (Netherlands)

    Takata, S.; Kimura, F.; van Houten, Frederikus J.A.M.; Westkamper, E.; Shpitalni, M.; Ceglarek, D.; Lee, J.

    2004-01-01

    As attention to environmental problems grows, product life cycle management is becoming a crucial issue in realizing a sustainable society. Our objective is to provide the functions necessary for such a society while minimizing material and energy consumption. From this viewpoint, we should redefine

  1. 10 CFR 435.8 - Life-cycle costing.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Life-cycle costing. 435.8 Section 435.8 Energy DEPARTMENT...-cycle costing. Each Federal agency shall determine life-cycle cost-effectiveness by using the procedures..., including lower life-cycle costs, positive net savings, savings-to-investment ratio that is estimated to be...

  2. Life cycle assessment of electronic waste treatment

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jinglan, E-mail: hongjing@sdu.edu.cn [Shandong Provincial Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100 (China); Shandong University Climate Change and Health Center, Public Health School, Shandong University, Jinan 250012 (China); Shi, Wenxiao [Shandong Provincial Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100 (China); Wang, Yutao [School of Life Science, Shandong University, Shanda South Road 27, Jinan 250100 (China); Chen, Wei [Shandong Provincial Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan 250100 (China); Li, Xiangzhi, E-mail: xiangzhi@sdu.edu.cn [School of Medicine, Shandong University, Jinan 250012 (China)

    2015-04-15

    Highlights: • Life cycle assessment of electronic waste recycling is quantified. • Key factors for reducing the overall environmental impact are indentified. • End-life disposal processes provide significant environmental benefits. • Efficiently reduce the improper disposal amount of e-waste is highly needed. • E-waste incineration can generate significant environmental burden. - Abstract: Life cycle assessment was conducted to estimate the environmental impact of electronic waste (e-waste) treatment. E-waste recycling with an end-life disposal scenario is environmentally beneficial because of the low environmental burden generated from human toxicity, terrestrial ecotoxicity, freshwater ecotoxicity, and marine ecotoxicity categories. Landfill and incineration technologies have a lower and higher environmental burden than the e-waste recycling with an end-life disposal scenario, respectively. The key factors in reducing the overall environmental impact of e-waste recycling are optimizing energy consumption efficiency, reducing wastewater and solid waste effluent, increasing proper e-waste treatment amount, avoiding e-waste disposal to landfill and incineration sites, and clearly defining the duties of all stakeholders (e.g., manufacturers, retailers, recycling companies, and consumers)

  3. Life Cycle Assessment - Theory and Practice

    DEFF Research Database (Denmark)

    Goldstein, Benjamin; Rasmussen, Freja Nygaard

    2017-01-01

    of the building tends to dominate environmental impacts, though as buildings become increasingly energy efficient, life cycle impacts shift towards other stages. LCA of built environments has been a useful supplement to mass-based urban environmental assessments, highlighting the importance of embodied...... environmental impacts in imported goods and showing interesting trade-offs between dense urban living and the greater purchasing power of wealthy urbanites. LCAs of human settlements also face difficult challenges; the long use stage (often decades) introduces high uncertainty regarding the end-of-life stage...

  4. Life cycle and sustainability of abrasive tools

    CERN Document Server

    Linke, Barbara

    2016-01-01

    This monograph focuses on abrasive tools for grinding, polishing, honing, and lapping operations. The book describes the life cycle of abrasive tools from raw material processing of abrasive grits and bonding, manufacturing of monolithic or multi-layered tools, tool use to tool end-of-life. Moreover, this work highlights sustainability challenges including economic, environmental, social and technological aspects. The target audience primarily comprises research and industry experts in the field of manufacturing, but the book may also be beneficial for graduate students.

  5. Methodologies for Social Life Cycle Assessment

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Le Bocq, Agathe; Nazakina, Liudmila

    2008-01-01

    stage in the product life cycle. Another very important difference among the proposals is their position towards the use of generic data. Several of the proposals argue that social impacts are connected to the conduct of the company leading to the conclusion that each individual company in the product......Goal, Scope and Background. In recent years several different approaches towards Social Life Cycle Assessment (SLCA) have been developed. The purpose of this review is to compare these approaches in order to highlight methodological differences and general shortcomings. SLCA has several...... and formulation of indicators. The indicators address a wide variety of issues; some approaches focus on impacts created in the very close proximity of the processes included in the product system, whereas others focus on the more remote societal consequences. Only very little focus has been given to the use...

  6. Life cycle management in product development

    DEFF Research Database (Denmark)

    Skelton, Kristen; Pattis, Anna

    2013-01-01

    The integration of Life Cycle Thinking (LCT) and Life Cycle Management (LCM) into business operations poses great challenges, as it requires a wider range of environmental responsibility often extending beyond a company's immediate control. Simultaneously, it offers many opportunities...... such as the reduction of a product's or industry’s environmental impacts, an increase in process efficiency or the interconnectedness within the organization itself or across a supply chain. Product development has been an area where application of LCM has been discussed most, since most product impacts are determined...... in the innovation and design phases. This comparative analysis explores the various approaches and challenges two companies are currently facing in their attempts to integrate LCT into their core product development processes....

  7. Life cycle assessment of waste paper management

    DEFF Research Database (Denmark)

    Merrild, Hanna Kristina; Damgaard, Anders; Christensen, Thomas Højlund

    2008-01-01

    The significance of technical data, as well as the significance of system boundary choices, when modelling the environmental impact from recycling and incineration of waste paper has been studied by a life cycle assessment focusing oil global warming potentials. The consequence of choosing...... results. The modelling showed that recycling of paper, from a life cycle point of view, is environmentally equal or better than incineration with energy recovery only when the recycling technology is at a high environmental performance level. However, the modelling also showed that expanding the system...... to include Substitution of fossil fuel energy by production of energy from the saved biomass associated with recycling will give a completely different result. In this case recycling is always more beneficial than incineration, thus increased recycling is desirable. Expanding the system to include forestry...

  8. Life Cycle Thinking in Impact Assessment

    DEFF Research Database (Denmark)

    Bidstrup, Morten

    2015-01-01

    It has been advocated that life cycle thinking (LCT) should be applied in impact assessment (IA) to a greater extent, since some development proposals pose a risk of significant impacts throughout the interconnected activities of product systems. Multiple authors have proposed the usage of life...... cycle assessment (LCA) for such analytical advancement, but little to no research on this tool application has been founded in IA practice so far. The aim of this article is to elaborate further on the gains assigned to application of LCA. The research builds on a review of 85 Danish IA reports, which...... reveal that LCT is appropriate for most of the IAs, but that LCA is rarely applied to provide such a perspective. Without LCA, the IAs show mixed performance in regard to LCT. Most IAs do consider the product provision of development proposals, but they rarely relate impacts to this function explicitly...

  9. Life-cycle design for sustainable architecture

    Directory of Open Access Journals (Sweden)

    Francesca Thiébat

    2013-05-01

    Full Text Available Sustainability in architecture should involve environmental and social aspects and also economic aspects. However, in a design process budget issues usually outweigh ecological aspects. How can we then drive clients and builders to put more socially responsible buildings on the market that do not exceed the fixed budget but are environmentally friendly? This paper propose an economic and environmental assessment tool to aid private or public building designers and owners to find the global sustainability value of a green building within a life cycle perspective. Sustainable life cycle tools for buildings design and construction help to achieve successfully integrated architecture. The research here presented proposes a new point of view of the “time-cost-quality triangle” of Project Management, by introducing three further aspects: environment, society and aesthetics.

  10. Confronting product life thinking with product life cycle analysis

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2001-01-01

    Industry is increasingly being confronted with the need to consider the whole life cycle effects of its products, in order to make environmental improvements of any significance. There is a danger that naive environmental decisions are made, due to apparent lack of data or actual lack of insight....... This paper describes a case study, where a class of students was presented with a product from the Danish company, Danfoss A/S, and given the task of carrying out an initial environmental evaluation of the product. This evaluation consisted of both a "life cycle check" and an exercise where the students were...... to "read" the environment out of the product, in order to systematically, quickly and efficiently come to some design recommendations for the company. The phrases "LCA" and "product life thinking" will be described and differentiated and a pattern identified for their cooperative effect in use....

  11. Security-related vulnerability life cycle analysis

    OpenAIRE

    Vache Marconato, Géraldine; Nicomette, Vincent; Kaâniche, Mohamed

    2012-01-01

    International audience; This paper deals with the characterization of security-related vulnerabilities based on public data reported in the Open Source Vulnerability Database. We focus on the analysis of vulnerability life cycle events corresponding to the vulnerability discovery, the vulnerability disclosure, the patch release, and the exploit availability. We study the distribution of the time between these events considering different operating systems (Windows, Unix, Mobile OS), and diffe...

  12. The Product Life Cycle of Durable Goods

    OpenAIRE

    Kaldasch, Joachim

    2011-01-01

    The model presented here derives the product life cycle of durable goods. It is based on the idea that the purchase process consists of first purchase and repurchase. First purchase is determined by the market penetration process (diffusion process), while repurchase is the sum of replacement and multiple purchase. The key property of durables goods is to have a mean lifetime in the order of several years. Therefore replacement purchase creates periodic variations of the unit sales (Juglar cy...

  13. Life Cycle Assessment of Plastic Bag Production

    OpenAIRE

    Ruban, Anna

    2012-01-01

    The main focus of this report is to establish a comparative study of traditional and biodegradable vest-plastic bag production through the utilization of a life cycle assessment (LCA) approach. The measurements were made for the Ukrainian limited liability company “Polymer”, as a representative manufacturer, in order to calculate the environmental impact of plastic bag manufacturing, and identify the more environmental friendly item. This research is based on a literature review of the specia...

  14. Life Cycle Management Strategies for Aging Engines

    Science.gov (United States)

    2003-02-01

    Reunions des specialistes des techniques de estion du cycle de vie pour vehicules aeriens vieillissants ] To order the complete compilation report, use...Mechanisms and Control. Specialists’ Meeting on Life Management Techniques for Ageing Air Vehicles [Les mecanismes vieillissants et le controle...protective coatings or surface modification treatments [3,7-9], while FOD can be repaired within limits, as detailed below [10]. 2.1.2. Internal

  15. Conceptual Framework To Extend Life Cycle Assessment ...

    Science.gov (United States)

    Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include near-field chemical sources (e.g., those originating from consumer products and building materials) that have traditionally been excluded from LCA. A new generation of rapid human exposure modeling and high-throughput toxicity testing is transforming chemical risk prioritization and provides an opportunity for integration of screening-level risk assessment (RA) with LCA. The combined LCA and RA approach considers environmental impacts of products alongside risks to human health, which is consistent with regulatory frameworks addressing RA within a sustainability mindset. A case study is presented to juxtapose LCA and risk screening approaches for a chemical used in a consumer product. The case study demonstrates how these new risk screening tools can be used to inform toxicity impact estimates in LCA and highlights needs for future research. The framework provides a basis for developing tools and methods to support decision making on the use of chemicals in products. This paper presents a conceptual framework for including near-field exposures into Life Cycle Assessment using advanced human exposure modeling and high-throughput tools

  16. 19 CFR 207.27 - Short life cycle products.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Short life cycle products. 207.27 Section 207.27... SUBSIDIZED EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.27 Short life... scope of the product category into which to classify the short life cycle merchandise identified by the...

  17. Total Life Cycle Management for the Special Operations Craft Riverine

    Science.gov (United States)

    2012-12-04

    Administration LCA Life Cycle Analysis LCC Life Cycle Cost LCM Life Cycle Management LMDSS Logistics Management Decision Support System LSC Life...Connors et al. (2002) defined life cycle analysis ( LCA ) as a formal process for establishing a quantitative basis in support of LCM decisions... LCA consists of: (i) building a model representation of a real world system or process, (ii) obtaining data to populate or instantiate the model, (iii

  18. An ideal sealed source life-cycle

    Energy Technology Data Exchange (ETDEWEB)

    Tompkins, Joseph Andrew [Los Alamos National Laboratory

    2009-01-01

    we have today. This regulation created a new regulatory framework seen as promising at the time. However, now they recognize that, despite the good intentions, the NIJWP/85 has not solved any source disposition problems. The answer to these sealed source disposition problems is to adopt a philosophy to correct these regulatory issues, determine an interim solution, execute that solution until there is a minimal backlog of sources to deal with, and then let the mechanisms they have created solve this problem into the foreseeable future. The primary philosophical tenet of the ideal sealed source life cycle follows. You do not allow the creation (or importation) of any source whose use cannot be justified, which cannot be affordably shipped, or that does not have a well-delinated and affordable disposition pathway. The path forward dictates that we fix the problem by embracing the Ideal Source Life cycle. In figure 1, we can see some of the elements of the ideal source life cycle. The life cycle is broken down into four portions, manufacture, use, consolidation, and disposition. These four arbitrary elements allow them to focus on the ideal life cycle phases that every source should go through between manufacture and final disposition. As we examine the various phases of the sealed source life cycle, they pick specific examples and explore the adoption of the ideal life cycle model.

  19. Maritime vessel obsolescence, life cycle cost and design service life

    Science.gov (United States)

    Dinu, O.; Ilie, A. M.

    2015-11-01

    Maritime vessels have long service life and great costs of building, manning, operating, maintaining and repairing throughout their life. Major actions are needed to repair, renovate, sometime built or even replace those scrapped when technology or demand changes determine obsolescence. It is regarded as a concern throughout vessel's entire life cycle and reflects changes in expectation regarding performances in functioning, safety and environmental effects. While service live may differ from physical lives, expectations about physical lives is the main factors that determines design service life. Performance and failure are illustrated conceptually and represented in a simplified form considering the evolution of vessels parameters during its service life. In the proposed methodology an accumulated vessel lifecycle cost is analyzed and obsolescence is characterized from ship's design, performances, maintenance and management parameters point of view. Romanian ports feeding Black Sea are investigated in order to provide comprehensive information on: number and types of vessels, transport capacity and life cycle length. Recommendations are to be made in order to insure a best practice in lifecycle management in order to reduce costs.

  20. Life cycle assessment of electronic waste treatment.

    Science.gov (United States)

    Hong, Jinglan; Shi, Wenxiao; Wang, Yutao; Chen, Wei; Li, Xiangzhi

    2015-04-01

    Life cycle assessment was conducted to estimate the environmental impact of electronic waste (e-waste) treatment. E-waste recycling with an end-life disposal scenario is environmentally beneficial because of the low environmental burden generated from human toxicity, terrestrial ecotoxicity, freshwater ecotoxicity, and marine ecotoxicity categories. Landfill and incineration technologies have a lower and higher environmental burden than the e-waste recycling with an end-life disposal scenario, respectively. The key factors in reducing the overall environmental impact of e-waste recycling are optimizing energy consumption efficiency, reducing wastewater and solid waste effluent, increasing proper e-waste treatment amount, avoiding e-waste disposal to landfill and incineration sites, and clearly defining the duties of all stakeholders (e.g., manufacturers, retailers, recycling companies, and consumers). Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.

    Directory of Open Access Journals (Sweden)

    Richard J Kraus

    2017-06-01

    Full Text Available When confronted with poor oxygenation, cells adapt by activating survival signaling pathways, including the oxygen-sensitive transcriptional regulators called hypoxia-inducible factor alphas (HIF-αs. We report here that HIF-1α also regulates the life cycle of Epstein-Barr virus (EBV. Incubation of EBV-positive gastric carcinoma AGS-Akata and SNU-719 and Burkitt lymphoma Sal and KemIII cell lines with a prolyl hydroxylase inhibitor, L-mimosine or deferoxamine, or the NEDDylation inhibitor MLN4924 promoted rapid and sustained accumulation of both HIF-1α and lytic EBV antigens. ShRNA knockdown of HIF-1α significantly reduced deferoxamine-mediated lytic reactivation. HIF-1α directly bound the promoter of the EBV primary latent-lytic switch BZLF1 gene, Zp, activating transcription via a consensus hypoxia-response element (HRE located at nt -83 through -76 relative to the transcription initiation site. HIF-1α did not activate transcription from the other EBV immediate-early gene, BRLF1. Importantly, expression of HIF-1α induced EBV lytic-gene expression in cells harboring wild-type EBV, but not in cells infected with variants containing base-pair substitution mutations within this HRE. Human oral keratinocyte (NOK and gingival epithelial (hGET cells induced to differentiate by incubation with either methyl cellulose or growth in organotypic culture accumulated both HIF-1α and Blimp-1α, another cellular factor implicated in lytic reactivation. HIF-1α activity also accumulated along with Blimp-1α during B-cell differentiation into plasma cells. Furthermore, most BZLF1-expressing cells observed in lymphomas induced by EBV in NSG mice with a humanized immune system were located distal to blood vessels in hypoxic regions of the tumors. Thus, we conclude that HIF-1α plays central roles in both EBV's natural life cycle and EBV-associated tumorigenesis. We propose that drugs that induce HIF-1α protein accumulation are good candidates for

  2. Life Cycle Assessment of Completely Recyclable Concrete.

    Science.gov (United States)

    De Schepper, Mieke; Van den Heede, Philip; Van Driessche, Isabel; De Belie, Nele

    2014-08-21

    Since the construction sector uses 50% of the Earth's raw materials and produces 50% of its waste, the development of more durable and sustainable building materials is crucial. Today, Construction and Demolition Waste (CDW) is mainly used in low level applications, namely as unbound material for foundations, e.g., in road construction. Mineral demolition waste can be recycled as crushed aggregates for concrete, but these reduce the compressive strength and affect the workability due to higher values of water absorption. To advance the use of concrete rubble, Completely Recyclable Concrete (CRC) is designed for reincarnation within the cement production, following the Cradle-to-Cradle (C2C) principle. By the design, CRC becomes a resource for cement production because the chemical composition of CRC will be similar to that of cement raw materials. If CRC is used on a regular basis, a closed concrete-cement-concrete material cycle will arise, which is completely different from the current life cycle of traditional concrete. Within the research towards this CRC it is important to quantify the benefit for the environment and Life Cycle Assessment (LCA) needs to be performed, of which the results are presented in a this paper. It was observed that CRC could significantly reduce the global warming potential of concrete.

  3. Life Cycle Assessment of Completely Recyclable Concrete

    Directory of Open Access Journals (Sweden)

    Mieke De Schepper

    2014-08-01

    Full Text Available Since the construction sector uses 50% of the Earth’s raw materials and produces 50% of its waste, the development of more durable and sustainable building materials is crucial. Today, Construction and Demolition Waste (CDW is mainly used in low level applications, namely as unbound material for foundations, e.g., in road construction. Mineral demolition waste can be recycled as crushed aggregates for concrete, but these reduce the compressive strength and affect the workability due to higher values of water absorption. To advance the use of concrete rubble, Completely Recyclable Concrete (CRC is designed for reincarnation within the cement production, following the Cradle-to-Cradle (C2C principle. By the design, CRC becomes a resource for cement production because the chemical composition of CRC will be similar to that of cement raw materials. If CRC is used on a regular basis, a closed concrete-cement-concrete material cycle will arise, which is completely different from the current life cycle of traditional concrete. Within the research towards this CRC it is important to quantify the benefit for the environment and Life Cycle Assessment (LCA needs to be performed, of which the results are presented in a this paper. It was observed that CRC could significantly reduce the global warming potential of concrete.

  4. When Product Life Cycle Meets Customer Activity Cycle

    DEFF Research Database (Denmark)

    Tan, Adrian Ronald

    2007-01-01

    project in a global office furniture manufacturer, this paper attempts to uncover how a manufacturing company is making the move from selling office furniture to selling the benefit of workspace performance. A significant insight is that the definition of value is core to both relationship marketing......Manufacturing companies have traditionally focused their efforts on designing, developing and producing products to offer on the market. Today global competition and demands for greater company responsibility of products throughout their entire life cycle are driving manufacturing companies...... to shift market strategies from a transactional approach to an approach based on the establishment and management of customer relationships (Grönroos, 1999). A growing number of studies and research programmes have focused on the potentials of business strategies based on providing the value of utility...

  5. Confronting product life thinking with product life cycle analysis

    OpenAIRE

    Tim C. McAloone

    2001-01-01

    Industry is increasingly being confronted with the need to consider the whole life cycle effects of its products, in order to make environmental improvements of any significance. There is a danger that naive environmental decisions are made, due to apparent lack of data or actual lack of insight. This paper describes a case study, where a class of students was presented with a product from the Danish company, Danfoss A/S, and given the task of carrying out an initial environmental evaluation ...

  6. Comparative Life Cycle Assessment between Warm SMA and Conventional SMA

    Science.gov (United States)

    2011-09-01

    This report presents the comparative life cycle assessment (LCA) between warm stone mastic asphalt (SMA) and conventional : SMA. Specifically, the study evaluated and compared the life cycle environmental and economic performances of two mixtures: a ...

  7. Life Cycle Impact Assessment Research Developments and Needs

    Science.gov (United States)

    Life Cycle Impact Assessment (LCIA) developments are explained along with key publications which record discussions which comprised ISO 14042 and SETAC document development, UNEP SETAC Life Cycle Initiative research, and research from public and private research institutions. It ...

  8. Life cycle assessment of shredder residue management

    DEFF Research Database (Denmark)

    Boldrin, Alessio; Damgaard, Anders; Brogaard, Line Kai-Sørensen

    This report provides a life-cycle assessment (LCA) of the treatment of shredder residue (SR) in Denmark. The LCA was conducted for the Environmental Protection Agency by DTU Environment in the period March-July 2014, as part of a service agreement between the Danish Environmental Protection Agency...... and the Technical University of Denmark on research-based services in the field of waste management. The report is part of a larger survey on improved resource recovery of waste, focusing on the environmental as well as socio-economic consequences of different treatment scenarios for shredder waste, impregnated...

  9. Life Cycle Assessment in Spatial Planning

    DEFF Research Database (Denmark)

    Bidstrup, Morten; Pizzol, Massimo; Schmidt, Jannick Højrup

    2015-01-01

    the spatial boundaries of a plan to further focus on global, indirect and cumulative impacts. These impacts are referred to as “systemic impacts”. This study proposes a Life Cycle Assessment (LCA) procedure which can be adopted in SEAs of various types of planning. The procedure represents a first step......Spatial planning establishes conditions for societal patterns of production and consumption. However, the assigned Strategic Environmental Assessments (SEA) tend to have a too narrow focus. In particular, there is a need for applying a system perspective in SEA, extending assessment beyond...... little attention, and it highlights the role of spatial planners in facilitating cleaner production....

  10. Geothermal life cycle assessment - part 3

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, J. L. [Argonne National Lab. (ANL), Argonne, IL (United States); Frank, E. D. [Argonne National Lab. (ANL), Argonne, IL (United States); Han, J. [Argonne National Lab. (ANL), Argonne, IL (United States); Elgowainy, A. [Argonne National Lab. (ANL), Argonne, IL (United States); Wang, M. Q. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2013-11-01

    A set of key issues pertaining to the environmental performance of geothermal electric power have been addressed. They include: 1) greenhouse gas emissions (GHG) from geothermal facilities, 2) the use of supercritical carbon dioxide (scCO2) as a geofluid for enhanced geothermal systems (EGS), 3) quantifying the impact of well field exploration on the life cycle of geothermal power, and finally 4) criteria pollutant emissions for geothermal and other electric power generation. A GHG emission rate (g/kWh) distribution as function of cumulative running capacity for California has been developed based on California and U. S. government data. The distribution is similar to a global distribution for compared geothermal technologies. A model has been developed to estimate life cycle energy of and CO2 emissions from a coupled pair of coal and EGS plants, the latter of which is powered by scCO2 captured from coal plant side. Depending on the CO2 capture rate on the coal side and the CO2 consumption rate on the EGS side, significant reductions in GHG emissions were computed when the combined system is compared to its conventional coal counterpart. In effect, EGS CO2 consumption acts as a sequestration mechanism for the coal plant. The effects CO2 emissions from the coupled system, prompt on the coal side and reservoir leakage on the EGS side, were considered as well as the subsequent decline of these emissions after entering the atmosphere over a time frame of 100 years. A model was also developed to provide better estimates of the impact of well field exploration on the life cycle performance of geothermal power production. The new estimates increase the overall life cycle metrics for the geothermal systems over those previously estimated. Finally, the GREET model has been updated to include the most recent criteria pollutant emissions for a range of renewable (including geothermal) and other power

  11. Publication Life Cycle at CERN Document Server

    CERN Multimedia

    Witowski, Sebastian; Costa, Flavio; Gabancho, Esteban; Marian, Ludmila; Tzovanakis, Harris

    2017-01-01

    This presentation guides listeners through all the stages of publication life cycle at CERN Document Server, from the ingestion using one of the various tools, through curation and processing, until the data is ready to be exported to other systems. It describes different tools that we are using to curate the incoming publications as well as to further improve the existing data on CDS. The second part of the talk goes through various challenges we have faced in the past and how we are going to overcome them in the new version of CDS.

  12. Life Cycle Assessment of Wall Systems

    Science.gov (United States)

    Ramachandran, Sriranjani

    Natural resource depletion and environmental degradation are the stark realities of the times we live in. As awareness about these issues increases globally, industries and businesses are becoming interested in understanding and minimizing the ecological footprints of their activities. Evaluating the environmental impacts of products and processes has become a key issue, and the first step towards addressing and eventually curbing climate change. Additionally, companies are finding it beneficial and are interested in going beyond compliance using pollution prevention strategies and environmental management systems to improve their environmental performance. Life-cycle Assessment (LCA) is an evaluative method to assess the environmental impacts associated with a products' life-cycle from cradle-to-grave (i.e. from raw material extraction through to material processing, manufacturing, distribution, use, repair and maintenance, and finally, disposal or recycling). This study focuses on evaluating building envelopes on the basis of their life-cycle analysis. In order to facilitate this analysis, a small-scale office building, the University Services Building (USB), with a built-up area of 148,101 ft2 situated on ASU campus in Tempe, Arizona was studied. The building's exterior envelope is the highlight of this study. The current exterior envelope is made of tilt-up concrete construction, a type of construction in which the concrete elements are constructed horizontally and tilted up, after they are cured, using cranes and are braced until other structural elements are secured. This building envelope is compared to five other building envelope systems (i.e. concrete block, insulated concrete form, cast-in-place concrete, steel studs and curtain wall constructions) evaluating them on the basis of least environmental impact. The research methodology involved developing energy models, simulating them and generating changes in energy consumption due to the above mentioned

  13. Addressing the effect of social life cycle assessments

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Dreyer, Louise Camilla; Wangel, Arne

    2012-01-01

    Purpose: In the recently published ‘Guidelines for social life cycle assessment of products’, it is stated that the ultimate objective of developing the social life cycle assessment (SLCA) is to promote improvements of social conditions for the stakeholders in the life cycle. This article address...

  14. 10 CFR 433.8 - Life-cycle costing.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Life-cycle costing. 433.8 Section 433.8 Energy DEPARTMENT... FEDERAL COMMERCIAL AND MULTI-FAMILY HIGH-RISE RESIDENTIAL BUILDINGS § 433.8 Life-cycle costing. Each Federal agency shall determine life-cycle cost-effectiveness by using the procedures set out in subpart A...

  15. US Federal LCA Commons Life Cycle Inventory Unit Process Template

    Science.gov (United States)

    The US Federal LCA Commons Life Cycle Inventory Unit Process Template is a multi-sheet Excel template for life cycle inventory data, metadata and other documentation. The template comes as a package that consistent of three parts: (1) the main template itself for life cycle inven...

  16. Replication-Competent Influenza A Virus That Encodes a Split-Green Fluorescent Protein-Tagged PB2 Polymerase Subunit Allows Live-Cell Imaging of the Virus Life Cycle

    Science.gov (United States)

    Avilov, Sergiy V.; Moisy, Dorothée; Munier, Sandie; Schraidt, Oliver

    2012-01-01

    Studies on the intracellular trafficking of influenza virus ribonucleoproteins are currently limited by the lack of a method enabling their visualization during infection in single cells. This is largely due to the difficulty of encoding fluorescent fusion proteins within the viral genome. To circumvent this limitation, we used the split-green fluorescent protein (split-GFP) system (S. Cabantous, T. C. Terwilliger, and G. S. Waldo, Nat. Biotechnol. 23:102–107, 2005) to produce a quasi-wild-type recombinant A/WSN/33/influenza virus which allows expression of individually fluorescent PB2 polymerase subunits in infected cells. The viral PB2 proteins were fused to the 16 C-terminal amino acids of the GFP, whereas the large transcomplementing GFP fragment was supplied by transient or stable expression in cultured cells that were permissive to infection. This system was used to characterize the intranuclear dynamics of PB2 by fluorescence correlation spectroscopy and to visualize the trafficking of viral ribonucleoproteins (vRNPs) by dynamic light microscopy in live infected cells. Following nuclear export, vRNPs showed a transient pericentriolar accumulation and intermittent rapid (∼1 μm/s), directional movements in the cytoplasm, dependent on both microtubules and actin filaments. Our data establish the potential of split-GFP-based recombinant viruses for the tracking of viral proteins during a quasi-wild-type infection. This new virus, or adaptations of it, will be of use in elucidating many aspects of influenza virus host cell interactions as well as in screening for new antiviral compounds. Furthermore, the existence of cell lines stably expressing the complementing GFP fragment will facilitate applications to many other viral and nonviral systems. PMID:22114331

  17. Modern architecture in a life cycle perspective

    DEFF Research Database (Denmark)

    Vestergaard, Inge

    2017-01-01

    By confronting the mistakes from the Modern Movement, the ideas of modernistic architecture are under pressure. This paper will summarize the primary architectural mistakes of the mono-functional thinking in planning and building and the non-appropriate environmental dispositions of the big plans...... points out the architectural consequences of prioritizing in the transformation process the social parameters higher than the original rigid architectural theories....... from the 60s and will suggest a holistic and broader life-cycle perspective on housing from the welfare society. On one hand, we care for the strong Modern Movements manifestoes in the form of architectural heritage. On the other hand, 600.000 dwelling-units in Denmark are suffering from degradation...... architectural transformations on city level and on housing level. The transformation goals are to secure the economy and the social and the environmental aspects in the transformation´s life-cycle perspective in order to make the buildings and the districts interact with and adapt to society. The conclusion...

  18. Developing Asset Life Cycle Management capabilities through the implementation of Asset Life Cycle Plans – an Action Research project

    NARCIS (Netherlands)

    Ruitenburg, Richard; Braaksma, Anne Johannes Jan

    2017-01-01

    Asset Life Cycle Management is a strategic approach to managing physical assets over their complete life cycle. However, the literature and the recent ISO 55,000 standard do not offer guidance as to how to develop such an approach. This paper investigates the main capabilities for Asset Life Cycle

  19. Comparative life cycle assessment and life cycle costing of lodging in the Himalaya

    NARCIS (Netherlands)

    Bhochhibhoya, Silu; Pizzol, Massimo; Achten, Wouter M.J.; Maskey, Ramesh Kumar; Zanetti, Michela; Cavalli, Raffaele

    2017-01-01

    Purpose: The main aim of the study is to assess the environmental and economic impacts of the lodging sector located in the Himalayan region of Nepal, from a life cycle perspective. The assessment should support decision making in technology and material selection for minimal environmental and

  20. From Life Cycle Costing to Economic Life Cycle Assessment—Introducing an Economic Impact Pathway

    Directory of Open Access Journals (Sweden)

    Sabrina Neugebauer

    2016-04-01

    Full Text Available Economic activities play a key role in human societies by providing goods and services through production, distribution, and exchange. At the same time, economic activities through common focus on short-term profitability may cause global crisis at all levels. The inclusion of three dimensions—environment, economy, and society—when measuring progress towards sustainable development has accordingly reached consensus. In this context, the Life cycle sustainability assessment (LCSA framework has been developed for assessing the sustainability performance of products through Life cycle assessment (LCA, Life cycle costing (LCC, and Social life cycle assessment (SLCA. Yet, the focus of common economic assessments, by means of LCC, is still on financial costs. However, as economic activities may have a wide range of positive and negative consequences, it seems particularly important to extend the scope of economic assessments. Foremost, as the limitation to monetary values triggers inconsistent implementation practice. Further aspects like missing assessment targets, uncertainty, common goods, or even missing ownership remain unconsidered. Therefore, we propose economic life cycle assessment (EcLCA for representing the economic pillar within the LCSA framework, following the requirements of ISO 14044, and introducing an economic impact pathway including midpoint and endpoint categories towards defined areas of protection (AoPs. We identify important target ratios by means of economic AoPs, which drive economic activities on the macro- and microeconomic level. Furthermore, we provide suggestions for midpoint and endpoint indicators representing the defined categories. With the presented EcLCA framework, a first step towards the inclusion of economic impacts within LCSA has been made. Relations between economic activities and resulting consequences are displayed, going beyond the cost-driven view of classical LCC. Further research and fine-tuning of

  1. Modeling the Ebolavirus Life Cycle with Transcription and Replication-Competent Viruslike Particle Assays.

    Science.gov (United States)

    Biedenkopf, Nadine; Hoenen, Thomas

    2017-01-01

    Ebolaviruses are the causative agent of a severe hemorrhagic fever with high case fatality rates, for which no approved specific therapy is available. As biosafety level 4 (BSL4) agents, work with live ebolaviruses is restricted to maximum containment laboratories. Transcription and replication-competent viruslike particle (trVLP) systems are reverse genetics-based life cycle modeling systems that allow researchers to model virtually the entire ebolavirus life cycle outside of a maximum containment laboratory. These systems can be used to dissect the virus life cycle, and thus increase our understanding of virus biology, as well as for more applied uses such as the screening and development of novel antivirals, and thus represent powerful tools for work on ebolaviruses.

  2. Life cycle implications of urban green infrastructure.

    Science.gov (United States)

    Spatari, Sabrina; Yu, Ziwen; Montalto, Franco A

    2011-01-01

    Low Impact Development (LID) is part of a new paradigm in urban water management that aims to decentralize water storage and movement functions within urban watersheds. LID strategies can restore ecosystem functions and reduce runoff loadings to municipal water pollution control facilities (WPCF). This research examines the avoided energy and greenhouse gas (GHG) emissions of select LID strategies using life cycle assessment (LCA) and a stochastic urban watershed model. We estimate annual energy savings and avoided GHG emissions of 7.3 GJ and 0.4 metric tons, respectively, for a LID strategy implemented in a neighborhood in New York City. Annual savings are small compared to the energy and GHG intensity of the LID materials, resulting in slow environmental payback times. This preliminary analysis suggests that if implemented throughout an urban watershed, LID strategies may have important energy cost savings to WPCF, and can make progress towards reducing their carbon footprint. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Modern architecture in a life cycle perspective

    DEFF Research Database (Denmark)

    Vestergaard, Inge

    2017-01-01

    By confronting the mistakes from the Modern Movement, the ideas of modernistic architecture are under pressure. This paper will summarize the primary architectural mistakes of the mono-functional thinking in planning and building and the non-appropriate environmental dispositions of the big plans...... from the 60s and will suggest a holistic and broader life-cycle perspective on housing from the welfare society. On one hand, we care for the strong Modern Movements manifestoes in the form of architectural heritage. On the other hand, 600.000 dwelling-units in Denmark are suffering from degradation...... and are inhabited by society’s most vulnerable people. The housing schemes are directly influenced by the fragmentation of the planning in a divided and segregated city. These ´Modern Cities´ have suffered from stigmatization ever since they were built. A positive development in society is that these living areas...

  4. PROJECT GOVERNANCE – PHASES AND LIFE CYCLE

    Directory of Open Access Journals (Sweden)

    Robbert Titus DEENEN

    2007-01-01

    Full Text Available When talking about projects, the barrier is clear: successful and failed. Some fail due to different reasons, but lack of good project and risk management played a large part. Others succeed largely because of the rigorous and disciplined application of good project practices. But both groups illustrate many points that underline and demonstrate important concepts applicable to current projects. Systematic application of good methods leads to successful outcomes in projects of all types. All projects are fundamentally dependent on people, and human beings are not very different today than we were hundreds, or even thousands, of years ago. This paper uncovers main elements in projects area such as the concepts and governance of projects, with an underline of the main characteristics and the projects phases and life cycle that erase the uncertainty that joins all the projects built at any time.

  5. Life Cycle Assessment of Sugar Production (VB)

    DEFF Research Database (Denmark)

    Teljigovic, Mehmed; Mengiardi, Jon; Factor, Gabriela

    1999-01-01

    The environmental organisation NOAH has proposed carrying out an environmental assessment of two different sugar productions (using sugar beet or sugar cane) in order to illustrate which of the systems has a higher environmental impact for sugar consumption in Denmark. Therefore a comparison...... will be made between sugar from sugar beet produced in Denmark versus sugar produces from sugar cane in a tropical country, Brazil, and transported afterwards to Denmark. To evaluate the environmental aspects of these two product systems a Life Cycle Assessement (LCA) will be carried out.From the results...... obtained in the present LCA of sugar produces from sugar canes or sugar beet it is difficult to make an immediate choice between the two possibilities. Indeed, Quantitative results from the EDIP (Environmental Design of Industrial Products) software are globally similar for both ways of producing sugar...

  6. The Information Warfare Life Cycle Model

    Directory of Open Access Journals (Sweden)

    Brett van Niekerk

    2011-03-01

    Full Text Available Information warfare (IW is a dynamic and developing concept, which constitutes a number of disciplines. This paper aims to develop a life cycle model for information warfare that is applicable to all of the constituent disciplines. The model aims to be scalable and applicable to civilian and military incidents where information warfare tactics are employed. Existing information warfare models are discussed, and a new model is developed from the common aspects of these existing models. The proposed model is then applied to a variety of incidents to test its applicability and scalability. The proposed model is shown to be applicable to multiple disciplines of information warfare and is scalable, thus meeting the objectives of the model.

  7. Life cycle costing with a discount rate

    Science.gov (United States)

    Posner, E. C.

    1978-01-01

    This article studies life cycle costing for a capability needed for the indefinite future, and specifically investigates the dependence of optimal policies on the discount rate chosen. The two costs considered are reprocurement cost and maintenance and operations (M and O) cost. The procurement price is assumed known, and the M and O costs are assumed to be a known function, in fact, a non-decreasing function, of the time since last reprocurement. The problem is to choose the optimum reprocurement time so as to minimize the quotient of the total cost over a reprocurement period divided by the period. Or one could assume a discount rate and try to minimize the total discounted costs into the indefinite future. It is shown that the optimum policy in the presence of a small discount rate hardly depends on the discount rate at all, and leads to essentially the same policy as in the case in which discounting is not considered.

  8. LIFE CYCLE ASSESSMENT FOR PC BLEND 2 AIRCRAFT RADOME DEPAINTER

    Science.gov (United States)

    This report describes the life cycle assessment on a potential replacement solvent blend for aircraft radome depainting at the Oklahoma City Air Logistics Center at Tinker Air Force Base. The life cycle assessment is composed of three separate but interrelated components: life cy...

  9. Life-Cycle Costing. Educational Facilities Digest 5.

    Science.gov (United States)

    Piele, Philip K.; Wright, Darrell

    Life-cycle costing is a management tool that may assist school administrators in making cost-effective decisions about building and improving school facilities. Life-cycle costing is defined as determining the total cost of building construction, operation, and maintenance over the assumed life of the building. An overview of the recent literature…

  10. 20th CIRP International Conference on Life Cycle Engineering

    CERN Document Server

    Song, Bin; Ong, Soh-Khim

    2013-01-01

    This edited volume presents the proceedings of the 20th CIRP LCE Conference, which cover various areas in life cycle engineering such as life cycle design, end-of-life management, manufacturing processes, manufacturing systems, methods and tools for sustainability, social sustainability, supply chain management, remanufacturing, etc.

  11. Life Cycle Design - a Route to the Sustainable Industrial Culture?

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Wenzel, Henrik; Alting, Leo

    1999-01-01

    In the attempt to reorient Society's development in a more sustainable direction attention is focused on the environmental impact of products and systems over their entire life cycle, but how can the environmental life cycle perspective be introduced into the design of new solutions and how much ...... is reviewed and the overall question of to what extent life cycle design is a route to the sustainable industrial culture is discussed.......In the attempt to reorient Society's development in a more sustainable direction attention is focused on the environmental impact of products and systems over their entire life cycle, but how can the environmental life cycle perspective be introduced into the design of new solutions and how much...... can be optained through life cycle design? The authors' experience with integration of environmental considerations in product development is presented, ranging from the detailed interactive approach to the EDIP-method through various simplified approaches. The potential for environmental improvements...

  12. MED-SUV Data Life Cycle

    Science.gov (United States)

    Sangianantoni, Agata; Puglisi, Giuseppe; Spampinato, Letizia; Tulino, Sabrina

    2015-04-01

    The MED-SUV project aims to implement a digital e-infrastructure for data access in order to promote the monitoring and study of key volcanic regions prone to volcanic hazards, and thus improve hazard assessment, according to the rationale of Supersite GEO initiative to Vesuvius- Campi Flegrei and Mt Etna, currently identified as Permanent Supersites. The present study focuses on the life cycle of MED-SUV data generated in the first period of the project and highlights the managing approach, as well as the crucial steps to be implemented for ensuring that data will be properly and ethically managed and can be used and accessed from both MED-SUV and the external community. The process is conceived outlining how research data being handled as the project progresses, describing what data are collected, processed or generated and how these data are going to be shared and made available through Open Access. Data cycle begins with their generation and ends with the deposit in the digital infrastructure, its key series of stages through which MED-SUV data passes are Collection, Data citation, Categorization of data, Approval procedure, Registration of datasets, Application of licensing models, and PID assignment. This involves a combination of procedures and practices taking into account the scientific core mission and the priorities of the project as well as the potential legal issues related to the management and protection of the Intellectual Property. We believe that the implementation of this process constitutes a significant encouragement in MED-SUV data sharing and as a consequence a better understanding on the volcanic processes, hazard assessment and a better integration with other Supersites projects.

  13. The life-cycle of operons.

    Science.gov (United States)

    Price, Morgan N; Arkin, Adam P; Alm, Eric J

    2006-06-01

    Operons are a major feature of all prokaryotic genomes, but how and why operon structures vary is not well understood. To elucidate the life-cycle of operons, we compared gene order between Escherichia coli K12 and its relatives and identified the recently formed and destroyed operons in E. coli. This allowed us to determine how operons form, how they become closely spaced, and how they die. Our findings suggest that operon evolution may be driven by selection on gene expression patterns. First, both operon creation and operon destruction lead to large changes in gene expression patterns. For example, the removal of lysA and ruvA from ancestral operons that contained essential genes allowed their expression to respond to lysine levels and DNA damage, respectively. Second, some operons have undergone accelerated evolution, with multiple new genes being added during a brief period. Third, although genes within operons are usually closely spaced because of a neutral bias toward deletion and because of selection against large overlaps, genes in highly expressed operons tend to be widely spaced because of regulatory fine-tuning by intervening sequences. Although operon evolution may be adaptive, it need not be optimal: new operons often comprise functionally unrelated genes that were already in proximity before the operon formed.

  14. The Life-cycle of Operons

    Energy Technology Data Exchange (ETDEWEB)

    Price, Morgan N.; Arkin, Adam P.; Alm, Eric J.

    2007-03-15

    Operons are a major feature of all prokaryotic genomes, buthow and why operon structures vary is not well understood. To elucidatethe life-cycle of operons, we compared gene order between Escherichiacoli K12 and its relatives and identified the recently formed anddestroyed operons in E. coli. This allowed us to determine how operonsform, how they become closely spaced, and how they die. Our findingssuggest that operon evolution may be driven by selection on geneexpression patterns. First, both operon creation and operon destructionlead to large changes in gene expression patterns. For example, theremoval of lysA and ruvA from ancestral operons that contained essentialgenes allowed their expression to respond to lysine levels and DNAdamage, respectively. Second, some operons have undergone acceleratedevolution, with multiple new genes being added during a brief period.Third, although genes within operons are usually closely spaced becauseof a neutral bias toward deletion and because of selection against largeoverlaps, genes in highly expressed operons tend to be widely spacedbecause of regulatory fine-tuning by intervening sequences. Althoughoperon evolution may be adaptive, it need not be optimal: new operonsoften comprise functionally unrelated genes that were already inproximity before the operon formed.

  15. Developmental Milestones Across the Programmatic Life Cycle

    Science.gov (United States)

    Glover-Kudon, Rebecca; DeGroff, Amy; Rohan, Elizabeth A.; Preissle, Judith; Boehm, Jennifer E.

    2015-01-01

    BACKGROUND In 2005 through 2009, the Centers for Disease Control and Prevention (CDC) funded 5 sites to implement a colorectal cancer screening program for uninsured, low-income populations. These 5 sites composed a demonstration project intended to explore the feasibility of establishing a national colorectal cancer screening program through various service delivery models. METHODS A longitudinal, multiple case study was conducted to understand and document program implementation processes. Using metaphor as a qualitative analytic technique, evaluators identified stages of maturation across the programmatic life cycle. RESULTS Analysis rendered a working theory of program development during screening implementation. In early stages, program staff built relationships with CDC and local partners around screening readiness, faced real-world challenges putting program policies into practice, revised initial program designs, and developed new professional skills. Midterm implementation was defined by establishing program cohesiveness and expanding programmatic reach. In later stages of implementation, staff focused on sustainability and formal program closeout, which prompted reflection about personal and programmatic accomplishments. CONCLUSIONS Demonstration sites evolved through common developmental stages during screening implementation. Findings elucidate ways to target technical assistance to more efficiently move programs along their maturation trajectory. In practical terms, the time and cost associated with guiding a program to maturity may be potentially shortened to maximize return on investment for both organizations and clients receiving service benefits. PMID:23868487

  16. The Life-cycle of Operons

    Energy Technology Data Exchange (ETDEWEB)

    Price, Morgan N.; Arkin, Adam P.; Alm, Eric J.

    2005-11-18

    Operons are a major feature of all prokaryotic genomes, but how and why operon structures vary is not well understood. To elucidate the life-cycle of operons, we compared gene order between Escherichia coli K12 and its relatives and identified the recently formed and destroyed operons in E. coli. This allowed us to determine how operons form, how they become closely spaced, and how they die. Our findings suggest that operon evolution is driven by selection on gene expression patterns. First, both operon creation and operon destruction lead to large changes in gene expression patterns. For example, the removal of lysA and ruvA from ancestral operons that contained essential genes allowed their expression to respond to lysine levels and DNA damage, respectively. Second, some operons have undergone accelerated evolution, with multiple new genes being added during a brief period. Third, although most operons are closely spaced because of a neutral bias towards deletion and because of selection against large overlaps, highly expressed operons tend to be widely spaced because of regulatory fine-tuning by intervening sequences. Although operon evolution seems to be adaptive, it need not be optimal: new operons often comprise functionally unrelated genes that were already in proximity before the operon formed.

  17. Automation life-cycle cost model

    Science.gov (United States)

    Gathmann, Thomas P.; Reeves, Arlinda J.; Cline, Rick; Henrion, Max; Ruokangas, Corinne

    1992-01-01

    The problem domain being addressed by this contractual effort can be summarized by the following list: Automation and Robotics (A&R) technologies appear to be viable alternatives to current, manual operations; Life-cycle cost models are typically judged with suspicion due to implicit assumptions and little associated documentation; and Uncertainty is a reality for increasingly complex problems and few models explicitly account for its affect on the solution space. The objectives for this effort range from the near-term (1-2 years) to far-term (3-5 years). In the near-term, the envisioned capabilities of the modeling tool are annotated. In addition, a framework is defined and developed in the Decision Modelling System (DEMOS) environment. Our approach is summarized as follows: Assess desirable capabilities (structure into near- and far-term); Identify useful existing models/data; Identify parameters for utility analysis; Define tool framework; Encode scenario thread for model validation; and Provide transition path for tool development. This report contains all relevant, technical progress made on this contractual effort.

  18. What roles for viruses in origin of life scenarios?

    Science.gov (United States)

    Kostyrka, Gladys

    2016-10-01

    Important roles in origin of life (OL) scenarios have been and still are attributed to viruses. Yet the strict dependence of viruses on cells for their multiplication has been widely acknowledged since the first decades of the 20th century. How could viruses play critical roles in the OL if life relies on cellular organization and if viruses are defined as parasites of cells? In other words, how could viruses play a role in the emergence of cellular life if the existence of cells is a prerequisite for the existence of viruses? This paper investigates this issue and describes past and current OL scenarios conferring viruses with important roles, thereby completing the work of historian of science and physician Scott Podolsky who identified three major roles of viruses in past OL scenarios. Some objections raised by present OL scenarios conferring viruses with an important role are discussed. I argue that disagreements concerning the roles of viruses in OL scenarios stem from the different concepts of life and of virus scientists defend. Investigating the roles of viruses in OL scenarios not only helps identifying different ways to define life in the context of OL theorizing. It also offers the opportunity to better understand how viruses could be conceptualized. The relevance of the replication-first versus metabolism-first dichotomy in OL theorizing is briefly discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Viruses and Life: Can There Be One Without the Other?

    OpenAIRE

    Jalasvuori, Matti; Bamford, Jaana

    2010-01-01

    Viruses are omnipresent, genetically replicating parasites in our biosphere that affect and drive the evolution of life in various ways. Are viruses an inevitable feature of all naturally emerged (although hypothetical) living systems in the Universe or are they only a specialty of our life on Earth? We argue in this discussion that viruses indeed might be present in extraterrestrial, independently emerged biospheres, at least if the process of the origin of life was similar to that on Earth....

  20. A life cycle database for parasitic acanthocephalans, cestodes, and nematodes

    Science.gov (United States)

    Benesh, Daniel P.; Lafferty, Kevin D.; Kuris, Armand

    2017-01-01

    Parasitologists have worked out many complex life cycles over the last ~150 years, yet there have been few efforts to synthesize this information to facilitate comparisons among taxa. Most existing host-parasite databases focus on particular host taxa, do not distinguish final from intermediate hosts, and lack parasite life-history information. We summarized the known life cycles of trophically transmitted parasitic acanthocephalans, cestodes, and nematodes. For 973 parasite species, we gathered information from the literature on the hosts infected at each stage of the parasite life cycle (8510 host-parasite species associations), what parasite stage is in each host, and whether parasites need to infect certain hosts to complete the life cycle. We also collected life-history data for these parasites at each life cycle stage, including 2313 development time measurements and 7660 body size measurements. The result is the most comprehensive data summary available for these parasite taxa. In addition to identifying gaps in our knowledge of parasite life cycles, these data can be used to test hypotheses about life cycle evolution, host specificity, parasite life-history strategies, and the roles of parasites in food webs.

  1. Alteration of cell cycle progression by Sindbis virus infection

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Ruirong; Saito, Kengo [Department of Molecular Virology, Graduate School of Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670 (Japan); Isegawa, Naohisa [Laboratory Animal Center, Graduate School of Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670 (Japan); Shirasawa, Hiroshi, E-mail: sirasawa@faculty.chiba-u.jp [Department of Molecular Virology, Graduate School of Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670 (Japan)

    2015-07-10

    We examined the impact of Sindbis virus (SINV) infection on cell cycle progression in a cancer cell line, HeLa, and a non-cancerous cell line, Vero. Cell cycle analyses showed that SINV infection is able to alter the cell cycle progression in both HeLa and Vero cells, but differently, especially during the early stage of infection. SINV infection affected the expression of several cell cycle regulators (CDK4, CDK6, cyclin E, p21, cyclin A and cyclin B) in HeLa cells and caused HeLa cells to accumulate in S phase during the early stage of infection. Monitoring SINV replication in HeLa and Vero cells expressing cell cycle indicators revealed that SINV which infected HeLa cells during G{sub 1} phase preferred to proliferate during S/G{sub 2} phase, and the average time interval for viral replication was significantly shorter in both HeLa and Vero cells infected during G{sub 1} phase than in cells infected during S/G{sub 2} phase. - Highlights: • SINV infection was able to alter the cell cycle progression of infected cancer cells. • SINV infection can affect the expression of cell cycle regulators. • SINV infection exhibited a preference for the timing of viral replication among the cell cycle phases.

  2. Life cycle assessment of regional brick manufacture

    Directory of Open Access Journals (Sweden)

    López-Aguilar, H. A.

    2016-06-01

    Full Text Available This document presents a Life Cycle Assessment (LCA study to quantify the environmental cradle-to-gate impact of the manufacture of brick for the construction industry, produced with material of igneous source. Its mineral composition and thermal isolation properties were characterized for use in real estate construction. The LCA results for brick manufacture using this material identified the greatest environmental impact to be associated with material extraction and its proportional cement content. Additionally, this document presents an evaluation of the environmental impact of the manufacturing process by comparing traditional fired clay brick and brick of the material under study. In conclusion, the studied material shows thermal insulation qualities and suitability for the manufacture of bricks with low incorporated energy.Este trabajo presenta un estudio de Análisis de Ciclo de Vida (ACV para cuantificar los impactos ambientales de la cuna a la puerta de la manufactura de ladrillos para la industria de la construcción, fabricados de un material de origen ígneo. Se caracterizó su composición mineralógica y propiedades de aislamiento térmico para ser usado en la construcción de inmuebles. Los resultados ACV de la fabricación de ladrillos de este material, identificaron la mayor contribución a los impactos ambientales asociados a la extracción del material y la cantidad proporcional de cemento. Adicionalmente, se presenta una evaluación comparativa del impacto ambiental entre la manufactura de un ladrillo tradicional de arcilla cocido y de un ladrillo del material en estudio. En conclusión el material estudiado muestra cualidades de aislamiento térmico y es adecuado para la fabricación de ladrillos con baja energía incorporada.

  3. Mainstreaming life cycle thinking through a consistent approach to footprints

    DEFF Research Database (Denmark)

    Ridoutt, Brad; Pfister, Stephan; Manzardo, Alessandro

    2016-01-01

    the auspices of the UNEP/SETAC Life Cycle Initiative project on environmental Life Cycle Impact Assessment has been working to develop generic guidance for developers of footprint metrics. The initial work involved forming a consensual position on the difference between footprints and existing LCA impact...

  4. sensitivity analysis on flexible road pavement life cycle cost model

    African Journals Online (AJOL)

    user

    8. REFERENCES. [1] Asta, G. “Life Cycle Cost Analysis of Asphalt and. Concrete Pavements” Thesis submitted to the School of Science and Engineering at Reykjavík University in impartial fulfillment of the requirements for the degree of Master of Science, Iceland. 2011. [2] Walls, J. I., & Smith, M. “Life-Cycle Cost Analysis in.

  5. LIFE CYCLE DESIGN OF AMORPHOUS SILICON PHOTOVOLTAIC MODULES

    Science.gov (United States)

    The life cycle design framework was applied to photovoltaic module design. The primary objective of this project was to develop and evaluate design metrics for assessing and guiding the Improvement of PV product systems. Two metrics were used to assess life cycle energy perform...

  6. Methods for uncertainty propagation in life cycle assessment

    NARCIS (Netherlands)

    Groen, E.A.; Heijungs, R.; Bokkers, E.A.M.; Boer, de I.J.M.

    2014-01-01

    Life cycle assessment (LCA) calculates the environmental impact of a product over its entire life cycle. Uncertainty analysis is an important aspect in LCA, and is usually performed using Monte Carlo sampling. In this study, Monte Carlo sampling, Latin hypercube sampling, quasi Monte Carlo sampling,

  7. Determination of HSE program proportional to organizational Corporate life cycles

    Directory of Open Access Journals (Sweden)

    2013-02-01

    Result: Corporate life cycles questionnaire with 10 indicators, available HSE programs score cards with 47 indicators according to OGP model and corporate life cycles proper programs table were results of this article. .Conclusion: The results showedweakness in the HSE programs implementation.Therefore, we offered the management methods like upgrade HSE culture and leadership for modification.

  8. Life cycle impacts of manufacturing redwood decking in Northern California

    Science.gov (United States)

    Richard D. Bergman; Elaine Oneil; Ivan L. Eastin; Han-Sup Han

    2014-01-01

    Awareness of the environmental footprint of building construction and use has led to increasing interest in green building. Defining a green building is an evolving process with life cycle inventory and life cycle impact assessment (LCIA) emerging as key tools in that evolution and definition process. This study used LCIA to determine the environmental footprint...

  9. From BIM to life cycle information management in infrastructure

    NARCIS (Netherlands)

    Nederveen, G.A. van; Wolfert, R.; Ruitenbeek, M. van de

    2014-01-01

    In principle, Building Information Modelling (BIM) should provide a basis for infrastructure information management during the whole life-cycle. In practice however, the use of BIM is normally limited to the design and construction phases. It seems that the use of BIM information in other life-cycle

  10. Dealing with Emergy Algebra in the Life Cycle Assessment Framework

    Science.gov (United States)

    The Life Cycle Inventory (LCI) represents one of the four steps of the Life Cycle Assessment (LCA) methodology, which is a standardized procedure (ISO 14040:2006) to estimate the environmental impacts generated by the production, use and disposal of goods and services. In this co...

  11. Comparative life cycle assessment and life cycle costing of lodging in the Himalaya

    DEFF Research Database (Denmark)

    Bhochhibhoya, Silu; Pizzol, Massimo; Achten, Wouter M J

    2017-01-01

    . Both primary and secondary data were used in the life cycle inventory. Results and discussion The modern building has the highest global warming potential (kg CO2-eq) as well as higher costs over 50 years of building lifespan. The results show that the use stage is responsible for the largest share...... of environmental impacts and costs, which are related to energy use for different household activities. The use of commercial materials in the modern building, which have to be transported mostly from the capital in the buildings, makes the higher GWP in the construction and replacement stages. Furthermore...

  12. Defining the baseline in social life cycle assessment

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Finkbeiner, Matthias; Jørgensen, Michael Søgaard

    2010-01-01

    the assessment will still meet the minimum criterion for validity of the assessment, that the assessment should be better than random in indicating the decision alternative with the most favourable social impacts. Based on this, it is concluded that the assessment of the non-implemented life cycle cannot...... be avoided since an assessment not taking into account the impacts of the non-implemented life cycle will not fulfil this minimum criterion. To mitigate the task of assessing the impacts of the non-implemented life cycle, new research areas are suggested, relating to simpler ways of performing the assessment...... valid assessments of the consequence of the decision that it is to support. The consequence of a decision to implement a life cycle of a product can be seen as the difference between the decision being implemented and 'non-implemented' product life cycle. This difference can to some extent be found...

  13. Firm Life Cycle, Book-Tax Differences and Earnings Persistence

    Directory of Open Access Journals (Sweden)

    Antonio Lopo Martinez

    2016-06-01

    Full Text Available The objective in this study is to show if the life cycle explains the relation between the Book-Tax Differences (BTDs and earnings persistence, as well as to inform on the future gains and their relation with the BTDs. Therefore, univariate tests were applied to verify the differences between the mean BTDS, life cycle stages and regression coefficient for the Earnings Before Income Tax (EBIT. The study focused on Brazilian publicly traded companies between 2009 and 2013. The results indicated that the control of earnings persistence was related with the stages of the life cycle. The information relevance of the life cycle and the Book-Tax Differences for earnings persistence is registered. In conclusion, the firm life cycle should be included in the analysis of the relation between the BTDs and earnings persistence. The evidence registered here is crucial to identify the quality of the earnings and incorporate them into earnings valuation models.

  14. Sustainable Urban Development Calls for Responsibility through Life Cycle Management

    Directory of Open Access Journals (Sweden)

    Miro Ristimäki

    2015-09-01

    Full Text Available Urban development bestows a great opportunity to increase sustainability in the built environment as cities are responsible for the majority of environmental impacts. However, the urban development process is fragmented and sub-optimization leads to unsustainable life cycle outcomes. The purpose of this study is to examine the urban development process from a life cycle perspective and identify how different actors understand life cycle management. By utilizing an inductive qualitative research design, 38 in-depth thematic interviews were conducted within the Finnish urban development industry including a case study and independent interviews from different phases of the urban development life cycle. The theoretical perspective is a combination of the ecosystem construct and life cycle management. Results show that there is no clear responsible actor for life cycle management in urban development. All actors claim that there is value to be added, mostly in economic, but also environmental and social terms. This study reveals that investors should be the responsible actor in the urban development process. By claiming responsibility and focusing on life cycle leadership we can improve sustainability in urban development, and respond to the urban sustainability challenge, thus improving the quality of life and welfare in our urban society.

  15. Life cycle analysis of transportation fuel pathways

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-02-24

    The purpose of this work is to improve the understanding of the concept of life cycle analysis (LCA) of transportation fuels and some of its pertinent issues among non-technical people, senior managers, and policy makers. This work should provide some guidance to nations considering LCA-based policies and to people who are affected by existing policies or those being developed. While the concept of employing LCA to evaluate fuel options is simple and straightforward, the act of putting the concept into practice is complex and fraught with issues. Policy makers need to understand the limitations inherent in carrying out LCA work for transportation fuel systems. For many systems, even those that have been employed for a 100 years, there is a lack of sound data on the performance of those systems. Comparisons between systems should ideally be made using the same tool, so that differences caused by system boundaries, allocation processes, and temporal issues can be minimized (although probably not eliminated). Comparing the results for fuel pathway 1 from tool A to those of fuel system 2 from tool B introduces significant uncertainty into the results. There is also the question of the scale of system changes. LCA will give more reliable estimates when it is used to examine small changes in transportation fuel pathways than when used to estimate large scale changes that replace current pathways with completely new pathways. Some LCA tools have been developed recently primarily for regulatory purposes. These tools may deviate from ISO principles in order to facilitate simplicity and ease of use. In a regulatory environment, simplicity and ease of use are worthy objectives and in most cases there is nothing inherently wrong with this approach, particularly for assessing relative performance. However, the results of these tools should not be confused with, or compared to, the results that are obtained from a more complex and rigorous ISO compliant LCA. It should be

  16. LIFE CYCLE ASSESSMENT ON GEOTHERMAL ENERGY SYSTEM.pdf

    OpenAIRE

    Nag, Rajat

    2016-01-01

    Life Cycle Assessment (LCA) addresses the environmental aspects and potential environmental impacts(e.g. use of resource and the environmental consequence of releases) through a product’s life cycle fromraw material acquisition through production, use, end-of-life treatment, recycling and final disposal(ISO14040). Renewable energy sources such as wind, tidal, solar, wave, geothermal, biomass have beenobserved as the potential solution to mitigate environmental pollution created by the use of ...

  17. Rules of Thumb in Life-Cycle Saving Decisions

    OpenAIRE

    Winter, Joachim K.; Schlafmann, Kathrin; Rodepeter, Ralf

    2011-01-01

    We analyse life-cycle saving decisions when households use simple heuristics, or rules of thumb, rather than solve the underlying intertemporal optimization problem. We simulate life-cycle saving decisions using three simple rules and compute utility losses relative to the solution of the optimization problem. Our simulations suggest that utility losses induced by following simple decision rules are relatively low. Moreover, the two main saving motives re ected by the canonical life-cyc...

  18. Life Cycle Assessment and Life Cycle Cost Analysis of Magnesia Spinel Brick Production

    Directory of Open Access Journals (Sweden)

    Aysun Özkan

    2016-07-01

    Full Text Available Sustainable use of natural resources in the production of construction materials has become a necessity both in Europe and Turkey. Construction products in Europe should have European Conformity (CE and Environmental Product Declaration (EPD, an independently verified and registered document in line with the European standard EN 15804. An EPD certificate can be created by performing a Life Cycle Assessment (LCA study. In this particular work, an LCA study was carried out for a refractory brick production for environmental assessment. In addition to the LCA, the Life Cycle Cost (LCC analysis was also applied for economic assessment. Firstly, a cradle-to-gate LCA was performed for one ton of magnesia spinel refractory brick. The CML IA method included in the licensed SimaPro 8.0.1 software was chosen to calculate impact categories (namely, abiotic depletion, global warming potential, acidification potential, eutrophication potential, human toxicity, ecotoxicity, ozone depletion potential, and photochemical oxidation potential. The LCC analysis was performed by developing a cost model for internal and external cost categories within the software. The results were supported by a sensitivity analysis. According to the results, the production of raw materials and the firing process in the magnesia spinel brick production were found to have several negative effects on the environment and were costly.

  19. Life cycle energy and GHG emission within the Turin metropolitan area urban water cycle

    OpenAIRE

    Zappone, Mariantonia; Fiore, Silvia; Genon, Giuseppe

    2014-01-01

    The aim of this study is to analyze the urban water cycle in the Turin Metropolitan Area (Northwestern Italy), with a focus on quantifying the annual life cycle energy consumption and greenhouse gas emissions. The study made use Material Flow Analysis and Life Cycle Assessment methods for a defined urban water cycle system (ATO3) operated by one water utility (SMAT S.p.A.), and examines all main sub-systems of the entire urban water cycle. The study quantified the annual direct and indirect e...

  20. Towards a Life Cycle Based Chemical Alternative Assessment (LCAA)

    DEFF Research Database (Denmark)

    Jolliet, O.; Huang, L.; Overcash, Michael

    2017-01-01

    ingredient in the product, first-order inter-compartmental transfer fractions and a matrix approach to determine Product Intake Fractions, and c) toxicity-related outcomes are compared with other life cycle impacts to evaluate the relevance of different impact categories for different consumer product...... demonstrates the feasibility of combining chemical specific Life Cycle Inventory from manufacturing database with near-field exposure assessment during product use and to compare the interest of various chemical alternatives. Considering consumer exposure during use phase is essential for both LCA and ACC......There is a need for an operational quantitative screening-level assessment of alternatives, that is life-cycle based and able to serve both Life cycle Assessment (LCA and chemical alternatives assessment (CAA). This presentation therefore aims to develop and illustrate a new approach called “Life...

  1. Viral and host proteins involved in picornavirus life cycle

    Directory of Open Access Journals (Sweden)

    Weng Kuo-Feng

    2009-11-01

    Full Text Available Abstract Picornaviruses cause several diseases, not only in humans but also in various animal hosts. For instance, human enteroviruses can cause hand-foot-and-mouth disease, herpangina, myocarditis, acute flaccid paralysis, acute hemorrhagic conjunctivitis, severe neurological complications, including brainstem encephalitis, meningitis and poliomyelitis, and even death. The interaction between the virus and the host is important for viral replication, virulence and pathogenicity. This article reviews studies of the functions of viral and host factors that are involved in the life cycle of picornavirus. The interactions of viral capsid proteins with host cell receptors is discussed first, and the mechanisms by which the viral and host cell factors are involved in viral replication, viral translation and the switch from translation to RNA replication are then addressed. Understanding how cellular proteins interact with viral RNA or viral proteins, as well as the roles of each in viral infection, will provide insights for the design of novel antiviral agents based on these interactions.

  2. Oil Points - Life Cycle Evaluations without the Data Problem

    DEFF Research Database (Denmark)

    Bey, Niki; Lenau, Torben Anker; Larsen, Michael Holm

    1999-01-01

    Environmental aspects of products in their whole life cycle are of increasing importance in industry [1]. Therefore, several methods and tools for environmental life cycle evaluation have been developed during the last years. Formal Life Cycle Assessment (LCA), the state-of-the-art in environmental...... indicator-based evaluation is dependent on the existence and availability of such indicators.In order to avoid this, the Oil Point Method (OPM) has been developed. Its application only requires limited resources while still providing a valuable evaluation. The OPM is based on primary energy considerations...

  3. Ecologically benign lubricants - Evaluation from a life cycle perspective

    Energy Technology Data Exchange (ETDEWEB)

    Herrmann, Christoph; Hesselbach, Juergen; Bock, Ralf; Zein, Andre; Oehlschlaeger, Gerlind; Dettmer, Tina [Institute of Machine Tools and Production Technology, Braunschweig University of Technology, Braunschweig (Germany)

    2007-11-15

    Using mineral oil based coolants for the machining of metals causes environmental problems. Besides plant seed oil, animal fat and used cooking oil proved to be raw material sources for alternative ester based coolants which can be used as substitutes for mineral oil. In this paper their properties are compared from a life cycle perspective with those of mineral oil and plant seed oil ester products regarding technical, ecological and economical aspects. In this context grinding tests, Life Cycle Assessment and Life Cycle Costing were performed. The three disciplines are brought together in a material flow model and, therefore, results are well harmonized. (Abstract Copyright [2007], Wiley Periodicals, Inc.)

  4. The biennial cycle of respiratory syncytial virus outbreaks in Croatia

    Directory of Open Access Journals (Sweden)

    Drazenovic Vladimir

    2008-01-01

    Full Text Available Abstract The paper analyses the epidemic pattern of respiratory syncytial virus (RSV outbreaks in children in Croatia. Over a period of 11 consecutive winter seasons (1994–2005 3,435 inpatients from Zagreb County aged from infancy to 10 years who were hospitalised with acute respiratory tract infections were tested for RSV-infection. RSV was identified in nasopharyngeal secretions of patients by virus isolation in cell culture and by detection of viral antigen with monoclonal antibodies. In the Zagreb area, RSV outbreaks were proven to vary in a two-year cycle, which was repeated every 23–25 months. This biennial cycle comprised one larger and one smaller season. Climate factors correlated significantly with the number of RSV cases identified only in the large seasons, which suggests that the biennial cycle is likely to continue regardless of meteorological conditions. Knowledge of this biennial pattern should be useful in predicting the onset of RSV outbreaks in Croatia, and would facilitate planning for the prevention and control of RSV infections in the region.

  5. Asset life cycle plans: twelve steps to assist strategic decision-making in asset life cycle management

    NARCIS (Netherlands)

    Ruitenburg, Richard Jacob; Braaksma, Anne Johannes Jan; van Dongen, Leonardus Adriana Maria; Carnero, Maria Carmen; Gonzalez-Prida, Vicente

    2017-01-01

    Effective management of physical assets should deliver maximum business value. Therefore, Asset Management standards such as PAS 55 and ISO 55000 ask for a life cycle approach. However, most existing methods focus only on the short term of the asset's life or the estimation of its remaining life.

  6. Life cycle management. Condition monitoring of wind power plants; Life-cycle-management. Zustandsueberwachung von Windenergieanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Wolff, R. [cmc GmbH, Kiel (Germany)

    2013-06-01

    The author of the contribution under consideration reports on maintenance strategies and condition monitoring in the field of wind energy. Beside the components in the drive train of wind turbines under consideration, the condition monitoring of the hardware systems and their software is explained. A brief overview of the field of machinery diagnosis and an explanation of the transmission of the measured data follow. Additional sensors such as sensors for the rotor blade monitoring, oil particles counter or oil quality sensors are described. In the field of diagnostic certainty, special follow-up studies such as video endoscopy, analysis of oil or grease, filter testing and material testing are discussed. The information from these thematic fields is used in the life-cycle management database for operationally relevant evaluations and considerations of economy of condition monitoring systems.

  7. Evidence that life history characteristics of wild birds influence infection and exposure to influenza A viruses.

    Directory of Open Access Journals (Sweden)

    Craig R Ely

    Full Text Available We report on life history characteristics, temporal, and age-related effects influencing the frequency of occurrence of avian influenza (AI viruses in four species of migratory geese breeding on the Yukon-Kuskokwim Delta, Alaska. Emperor geese (Chen canagica, cackling geese (Branta hutchinsii, greater white-fronted geese (Anser albifrons, and black brant (Branta bernicla, were all tested for active infection of AI viruses upon arrival in early May, during nesting in June, and while molting in July and August, 2006-2010 (n = 14,323. Additionally, prior exposure to AI viruses was assessed via prevalence of antibodies from sera samples collected during late summer in 2009 and 2010. Results suggest that geese are uncommonly infected by low pathogenic AI viruses while in Alaska. The percent of birds actively shedding AI viruses varied annually, and was highest in 2006 and 2010 (1-3% and lowest in 2007, 2008, and 2009 (95% for emperor geese, a species that spends part of its life cycle in Asia and is endemic to Alaska and the Bering Sea region, compared to 40-60% for the other three species, whose entire life cycles are within the western hemisphere. Birds <45 days of age showed little past exposure to AI viruses, although antibodies were detected in samples from 5-week old birds in 2009. Seroprevalence of known age black brant revealed that no birds <4 years old had seroconverted, compared to 49% of birds ≥4 years of age.

  8. Family influences on the career life cycle

    OpenAIRE

    Beauregard, T. Alexandra

    2007-01-01

    This chapter examines the myriad ways in which one’s family and personal life can impact an individual’s career. A review of some of the key research literature reveals that career choice is influenced by an individual’s values, attitudes, and expectations concerning how work should be balanced with the rest of life. Individuals are also susceptible to influence from their families of origin with regard to occupational choice and prioritizing work over family, or vice versa. Career opportunit...

  9. EASEWASTE-life cycle modeling capabilities for waste management technologies

    DEFF Research Database (Denmark)

    Bhander, Gurbakhash Singh; Christensen, Thomas Højlund; Hauschild, Michael Zwicky

    2010-01-01

    and methods The EASEWASTE model supports a full life cycle assessment of any user defined residential, bulky waste or garden waste management system. The model focuses on the major components of the waste and reviews each component in terms of the available waste management options, including bio...... waste management systems applying a life-cycle perspective requires readily understandable tools for modelling the life cycle impacts of waste management systems. The aim of the paper is to demonstrate the structure, functionalities and LCA modelling capabilities of the PC-based life cycle oriented......-gasification and composting, thermal treatment incineration, use-on-land, material sorting and recycling, bottom and fly ash handling, material and energy utilization and landfilling. In order to allow the use of the model in an early stage where local data may be limited, default data sets are provided for waste composition...

  10. Life cycle assessment of a wind farm and related externalities

    DEFF Research Database (Denmark)

    Schleisner, Liselotte

    2000-01-01

    This paper concentrates on the assessment of energy and emissions related to the production and manufacture of materials for an offshore wind farm as well as a wind farm on land based on a life cycle analysis (LCA) model. In Denmark a model has been developed for life cycle assessments of different...... materials. The model is able to assess the energy use related to the production, transportation and manufacture of 1 kg of material. The energy use is divided into fuels used in order to estimate the emissions through the life cycle. In the paper the model and the attached assumptions are described......, and the model is demonstrated for two wind farms. The externalities for the wind farms are reported, showing the importance of life cycle assessment for renewable energy technologies. (C) 2000 Elsevier Science Ltd. All rights reserved....

  11. Life Cycle Engineering – from methodology to enterprise culture

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Alting, Leo; Poll, Christian

    2003-01-01

    As part of a sustainable development, the environmental efficiency of industry must increase by a factor four to ten. This engenders attention to the environmental impact of products and technical systems over their entire life cycle. The last decade has seen the development of a number...... of methodologies and tools for life cycle assessment and development of more eco-efficient products, from complex to simplified, catering to the needs of especially small and medium-sized enterprizes. The tools and data are in place, but dissemination lacks behind. Propagation of life cycle thinking and life cycle...... engineering to larger parts of industry is attempted by strengthening the market pull through integrated product policy measures, and at the same time pushing through information activities, training and dissemination of tools. Experience hitherto shows that these forces are insufficient and that stronger...

  12. Electric vehicle life cycle cost analysis : final research project report.

    Science.gov (United States)

    2017-02-01

    This project compared total life cycle costs of battery electric vehicles (BEV), plug-in hybrid electric vehicles (PHEV), hybrid electric vehicles (HEV), and vehicles with internal combustion engines (ICE). The analysis considered capital and operati...

  13. Estimating pesticide emissions for life cycle assessment of agricultural products

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Røpke, Inge

    2004-01-01

    As the first country in Europe Denmark almost 2 years ago established an official center for Life Cycle Assessments and life cycle approaches as an element of the national IPP (Integrated Product Policy). The Danish EPA lends financial support to this important initiative, the aim of which is to: 1....... promote the use of Life Cycle Assessment and other product-oriented environmental tools in companies, 2. support companies and other in using environmental assessment of products and services, 3. ensure that the effort in the LCA area is based on a solid and scientific basis, and 4. maintain the well...... evaluation finished in September 2004. Important learnings for all who are engaged in dissemination of life cycle thinking in industry will be presented....

  14. Secure Software Development Life Cycle Processes: A Technology Scouting Report

    National Research Council Canada - National Science Library

    Davis, Noopur

    2005-01-01

    .... The purpose of this technical note is to present overview information about existing processes, standards, life cycle models, frameworks, and methodologies that support or could support secure software development...

  15. Life cycles of research groups: the case of CWTS

    NARCIS (Netherlands)

    Braam, R.; van den Besselaar, P.A.A.

    2010-01-01

    By combining concepts from scientometrics and organisation studies, we hypothesise a basic 'life cycle' of organisational research units (institutes, laboratories or groups), if internal and external conditions are stable. Three output indicators enable a comparison of historical patterns with the

  16. Environmental life cycle assessment of water supply in South Africa ...

    African Journals Online (AJOL)

    , which is increasingly used for decision-support in the South African manufacturing industry, e.g. for cleaner production purposes. The life cycle impact assessment (LCIA) phase of LCAs evaluates the potential environmental impact profiles of ...

  17. A new data architecture for advancing life cycle assessment

    Science.gov (United States)

    IntroductionLife cycle assessment (LCA) has a technical architecture that limits data interoperability, transparency, and automated integration of external data. More advanced information technologies offer promise for increasing the ease with which information can be synthesized...

  18. Environmentally sensitive life-cycle traits have low elasticity

    DEFF Research Database (Denmark)

    Forbes, Valery E.; Olsen, Mette; Palmqvist, Annemette

    2010-01-01

    The relationships between population growth rate and the life-cycle traits contributing to it are nonlinear and variable. This has made it difficult for ecologists to consistently predict changes in population dynamics from observations on changes in life-cycle traits. We show that traits having...... a high sensitivity to chemical toxicants tend to have a low elasticity, meaning that changes in them have a relatively low impact on population growth rate, compared to other life-cycle traits. This makes evolutionary sense in that there should be selection against variability in population growth rate....... In particular, we found that fecundity was generally more sensitive to chemical stress than was juvenile or adult survival or time to first reproduction, whereas fecundity typically had a lower elasticity than the other life-cycle traits. Similar relationships have been recorded in field populations for a wide...

  19. Life cycle and economic efficiency analysis: durable pavement markings.

    Science.gov (United States)

    2009-07-01

    This project examined the life cycle and economic efficiency of two pavement marking : materials inlaid tape and thermoplastic to find the most economical product for specific : traffic and weather conditions. Six locations in the state of Ma...

  20. Life Cycle Costs in Education: Operations & Maintenance Considered.

    Science.gov (United States)

    Moussatche, Helena; Languell-Urquhart, Jennifer; Woodson, Carol

    2000-01-01

    Discusses life cycle cost analysis when deciding on flooring finishes and examines operations and maintenance cost effectiveness relative to hard, resilient, and soft flooring. A chart of evaluated flooring materials' characteristics, appropriate maintenance procedures, and recommended frequency is included. (GR)

  1. Life-cycle analysis of renewable energy systems

    DEFF Research Database (Denmark)

    Sørensen, Bent

    1994-01-01

    An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants......An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants...

  2. Creative Careers: The Life Cycles of Nobel Laureates in Economics

    OpenAIRE

    Weinberg, Bruce A.; David W. Galenson

    2005-01-01

    This paper studies life cycle creativity among Nobel laureate economists. We identify two distinct life cycles of scholarly creativity. Experimental innovators work inductively, accumulating knowledge from experience. Conceptual innovators work deductively, applying abstract principles. We find that conceptual innovators do their most important work earlier in their careers than experimental laureates. For instance, our estimates imply that the probability that the most conceptual laureate pu...

  3. The life cycle of social and economic systems

    OpenAIRE

    S.E. Sardak

    2016-01-01

    The aim of the article. The aim of the article is to identify the components of social and economic systems life cycle. To achieve this aim, the article describes the traits and characteristics of the system, determines the features of social and economic systems functioning and is applied a systematic approach in the study of their life cycle. The results of the analysis. It is determined that the development of social and economic systems has signs of cyclicity and is explained methodolo...

  4. Life Cycle Costing in a Dynamic Environment.

    Science.gov (United States)

    1983-01-01

    Engineering, Directorate of Maintenance and Supply, Acquisition and Com- munications Group (HQ USAF/ LEYE ) is the office of primary responsibility (OPE...cycle~ costs are an important consideration have the characteris- tics of a classical investment problem. These problems con- cern whether or not the...Gene Tattini HQ USAF/ LEYE Lt Col Don Crawford HQ AFSC/ACCF Mr Frank Fong HQ AFSC/ACCE Mr John Rosso HQ AFSC/ALPA mr Vern Menker ISD/ACCL Capt Arnie

  5. The Life-Cycle Policy model

    NARCIS (Netherlands)

    Anciaux, N.L.G.; Bouganim, Luc; van Heerde, H.J.W.; Pucheral, Philippe; Apers, Peter M.G.

    Our daily life activity leaves digital trails in an increasing number of databases (commercial web sites, internet service providers, search engines, location tracking systems, etc). Personal digital trails are commonly exposed to accidental disclosures resulting from negligence or piracy and to

  6. Models of life: epigenetics, diversity and cycles

    Science.gov (United States)

    Sneppen, Kim

    2017-04-01

    This review emphasizes aspects of biology that can be understood through repeated applications of simple causal rules. The selected topics include perspectives on gene regulation, phage lambda development, epigenetics, microbial ecology, as well as model approaches to diversity and to punctuated equilibrium in evolution. Two outstanding features are repeatedly described. One is the minimal number of rules to sustain specific states of complex systems for a long time. The other is the collapse of such states and the subsequent dynamical cycle of situations that restitute the system to a potentially new metastable state.

  7. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 1, Data Analysis-The Deliverables provides a comprehensive treatment of data analysis within the systems development life-cycle and all the deliverables that need to be collected in analysis. The purpose of deliverables is explained and a number of alternative ways of collecting them are discussed. This book is comprised of five chapters and begins with an overview of what """"analysis"""" actually means, with particular reference to tasks such as hardware planning and software evaluation and where they fit into the overall cycle. The ne

  8. Replication Cycle and Molecular Biology of the West Nile Virus

    Science.gov (United States)

    Brinton, Margo A.

    2013-01-01

    West Nile virus (WNV) is a member of the genus Flavivirus in the family Flaviviridae. Flaviviruses replicate in the cytoplasm of infected cells and modify the host cell environment. Although much has been learned about virion structure and virion-endosomal membrane fusion, the cell receptor(s) used have not been definitively identified and little is known about the early stages of the virus replication cycle. Members of the genus Flavivirus differ from members of the two other genera of the family by the lack of a genomic internal ribosomal entry sequence and the creation of invaginations in the ER membrane rather than double-membrane vesicles that are used as the sites of exponential genome synthesis. The WNV genome 3' and 5' sequences that form the long distance RNA-RNA interaction required for minus strand initiation have been identified and contact sites on the 5' RNA stem loop for NS5 have been mapped. Structures obtained for many of the viral proteins have provided information relevant to their functions. Viral nonstructural protein interactions are complex and some may occur only in infected cells. Although interactions between many cellular proteins and virus components have been identified, the functions of most of these interactions have not been delineated. PMID:24378320

  9. A Simple Bounded-Rationality Life Cycle Model

    NARCIS (Netherlands)

    Binswanger, J.

    2008-01-01

    Life cycle saving decisions belong to the most complex financial decisions that we are faced with in our life. Psychologists have found that when making complex decisions people use short-cuts in the form of minimum requirements for particular attribute categories of choice options. This paper

  10. Life-cycle stages of Dinophysis acuminata (Dinophyceae) in the ...

    African Journals Online (AJOL)

    Despite many observations of different life-cycle stages of Dinophysis species, the complete life history of the genus is still unknown owing to the difficulties encountered in culturing these species. The seasonal distribution of D. acuminata was followed at two offshore stations in the brackish Baltic Sea by means of in situ ...

  11. Moonstruck how lunar cycles affect life

    CERN Document Server

    Naylor, Ernest

    2015-01-01

    Throughout history, the influence of the full Moon on humans and animals has featured in folklore and myths. Yet it has become increasingly apparent that many organisms really are influenced indirectly, and in some cases directly, by the lunar cycle. Breeding behaviour among some marine animals has been demonstrated to be controlled by internal circalunar biological clocks, to the point where lunar-daily and lunar-monthly patterns of Moon-generated tides are embedded in their genes. Yet, intriguingly, Moon-related behaviours are also found in dry land and fresh water species living far beyond the influence of any tides. In Moonstruck, Ernest Naylor dismisses the myths concerning the influence of the Moon, but shows through a range of fascinating examples the remarkable real effects that we are now finding through science. He suggests that since the advent of evolution on Earth, which occurred shortly after the formation of the Moon, animals evolved adaptations to the lunar cycle, and considers whether, if Moo...

  12. Life Cycle Well Integrity and Reliability

    OpenAIRE

    Haaland, Bjarne

    2017-01-01

    Master's thesis for Petroleum engineering This thesis presents a method for reliability based casing design. The method is inspired by the model described by Das et al. (2015) - A model for Well Reliability Analysis throughout the Life of a Well Using Barrier Engineering and Performance (1). The purpose of this model is to show how reliability based casing design, based on statistical data, can be performed in practice. Monte Carlo simulation conducted in MATLAB is the basis of the app...

  13. 76 FR 41525 - Hewlett Packard Global Parts Supply Chain, Global Product Life Cycles Management Unit Including...

    Science.gov (United States)

    2011-07-14

    ... Employment and Training Administration Hewlett Packard Global Parts Supply Chain, Global Product Life Cycles... Chain, Global Product Life Cycles Management Unit, including teleworkers reporting to Houston, Texas... Parts Supply Chain, Global Product Life Cycles Management Unit, including teleworkers reporting to...

  14. Life Cycle Assessment of a Natural Gas Combined Cycle Power Generation System

    Energy Technology Data Exchange (ETDEWEB)

    Spath, P.L.; Mann, M.K.

    2000-12-27

    Natural gas is used for steam and heat production in industrial processes, residential and commercial heating, and electric power generation. Because of its importance in the power mix, a life cycle assessment on electricity generation via a natural gas combined cycle system has been performed.

  15. An Analysis of Program Managers as Total Life Cycle Systems Managers

    Science.gov (United States)

    2017-09-01

    Life Cycle Management Command TLCM Total Life Cycle Manager TLCSM Total Life Cycle Systems Management TMRR Technology Maturation and Risk Reduction...life cycle management responsibility away from the PM to the LCMC during sustainment phase ( Enterprise Information Systems, 2011), which directly...to optimize life cycle systems management , regardless of whether there is a “total” life cycle manager ? 6. Do DOD enterprise initiatives such as

  16. Life Cycle Reversal in Aurelia sp.1 (Cnidaria, Scyphozoa.

    Directory of Open Access Journals (Sweden)

    Jinru He

    Full Text Available The genus Aurelia is one of the major contributors to jellyfish blooms in coastal waters, possibly due in part to hydroclimatic and anthropogenic causes, as well as their highly adaptive reproductive traits. Despite the wide plasticity of cnidarian life cycles, especially those recognized in certain Hydroza species, the known modifications of Aurelia life history were mostly restricted to its polyp stage. In this study, we document the formation of polyps directly from the ectoderm of degenerating juvenile medusae, cell masses from medusa tissue fragments, and subumbrella of living medusae. This is the first evidence for back-transformation of sexually mature medusae into polyps in Aurelia sp.1. The resulting reconstruction of the schematic life cycle of Aurelia reveals the underestimated potential of life cycle reversal in scyphozoan medusae, with possible implications for biological and ecological studies.

  17. 19th CIRP Conference on Life Cycle Engineering

    CERN Document Server

    Linke, Barbara

    2012-01-01

    The 19th CIRP Conference on Life Cycle Engineering continues a strong tradition of scientific meetings in the areas of sustainability and engineering within the community of the International Academy for Production Engineering (CIRP). The focus of the conference is to review and discuss the current developments, technology improvements, and future research directions that will allow engineers to help create green businesses and industries that are both socially responsible and economically successful.  The symposium covers a variety of relevant topics within life cycle engineering including Businesses and Organizations, Case Studies, End of Life Management, Life Cycle Design, Machine Tool Technologies for Sustainability, Manufacturing Processes, Manufacturing Systems, Methods and Tools for Sustainability, Social Sustainability, and Supply Chain Management.

  18. Role of nondestructive evaluation in life cycle management

    Energy Technology Data Exchange (ETDEWEB)

    Martz, H.

    1997-12-18

    This paper provides an overview of some common NDE methods and several examples for the use of different NDE techniques throughout the life cycle of a product. NDE techniques are being used to help determine material properties, design new implants, extend the service life of aircraft, and help dispose of radioactive waste in a safe manner. It is the opinion of this author and others that the NDE community needs to work more closely with end users in the life cycle of a product to better incorporate NDE techniques. The NDE community needs to highlight the importance of NDE in the entire life-cycle process of a product by showing real costs savings to the manufacturing community.

  19. Life Cycle and Suicidal Behavior among Women

    Directory of Open Access Journals (Sweden)

    Pablo Mendez-Bustos

    2013-01-01

    Full Text Available It is nowadays accepted that, independently of methodological issues, women commit fewer suicides than men but make more frequent attempts. Yet, female suicidal risk varies greatly along the lifetime and is linked to the most significant moments in it. A wide analysis of the existing literature was performed to provide a narrative description on the evolution of female suicidal rates from childhood to old age, considering the milestones in their life history. A detailed analysis of gender differences in suicidal behavior is key to establish preventive measures and priorities. More specific studies are needed to adapt future interventions on female suicide.

  20. The NCI Thesaurus quality assurance life cycle.

    Science.gov (United States)

    de Coronado, Sherri; Wright, Lawrence W; Fragoso, Gilberto; Haber, Margaret W; Hahn-Dantona, Elizabeth A; Hartel, Francis W; Quan, Sharon L; Safran, Tracy; Thomas, Nicole; Whiteman, Lori

    2009-06-01

    The National Cancer Institute Enterprise Vocabulary Services (NCI EVS) uses a wide range of quality assurance (QA) techniques to maintain and extend NCI Thesaurus (NCIt). NCIt is a reference terminology and biomedical ontology used in a growing number of NCI and other systems that extend from translational and basic research through clinical care to public information and administrative activities. Both automated and manual QA techniques are employed throughout the editing and publication cycle, which includes inserting and editing NCIt in NCI Metathesaurus. NCI EVS conducts its own additional periodic and ongoing content QA. External reviews, and extensive evaluation by and interaction with EVS partners and other users, have also played an important part in the QA process. There have always been tensions and compromises between meeting the needs of dependent systems and providing consistent and well-structured content; external QA and feedback have been important in identifying and addressing such issues. Currently, NCI EVS is exploring new approaches to broaden external participation in the terminology development and QA process.

  1. Life cycle water footprints of nonfood biomass fuels in China.

    Science.gov (United States)

    Zhang, Tingting; Xie, Xiaomin; Huang, Zhen

    2014-04-01

    This study presented life cycle water footprints (WFs) of biofuels from biomass in China based on the resource distribution, climate conditions, soil conditions and crop growing characteristics. Life cycle WFs including blue, green and gray water were evaluated for the selected fuel pathways. Geographical differences of water requirements were revealed to be different by locations. The results indicated that water irrigation requirements were significantly different from crop to crop, ranging from 2-293, 78-137, and 17-621 m(3)/ha, for sweet sorghum, cassava, and Jatropha curcas L., respectively. Four biofuel pathways were selected on this basis to analyze the life cycle WF: cassava based bioethanol in Guangxi, sweet sorghum based bioethanol in Northeast China, Jatropha curcal L. based biodiesel in Yunnan and microalgae based biodiesel in Hainan. The life cycle WFs of bioethanol from cassava and sweet sorghum were 3708, and 17 156 m(3) per ton of bioethanol, respectively, whereas for biodiesel produced from Jatropha curcas L. and microalgae, they were 5787, and 31 361 m(3) per ton of biodiesel, respectively. The crop growing stage was the main contributor to the whole life cycle of each pathway. Compared to blue and green water, gray water was significant due to the use of fertilizer during the growing of biomass. From the perspective of the WF, cassava based bioethanol in Guangxi and Jatropha based biodiesel in Yunnan were suitable for promotion, whereas the promotion for microalage based biodiesel in Hainan required improvement on technology.

  2. Predicting product life cycle using fuzzy neural network

    Directory of Open Access Journals (Sweden)

    Ali Mohammadi

    2014-09-01

    Full Text Available One of the most important tasks of science in different fields is to find the relationships among various phenomena in order to predict future. Production and service organizations are not exceptions and they should predict future to survive. Predicting the life cycle of the organization's products is one of the most important prediction cases in an organization. Predicting the product life cycle provides an opportunity to identify the product position and help to get a better insight about competitors. This paper deals with the predictability of the product life cycle with Adaptive Network-Based Fuzzy Inference System (ANFIS. The Population of this study was Pegah Fars products and the sample was this company's cheese products. In this regard, this paper attempts to model and predict the product life cycle of cheese products in Pegah Fars Company. In this due, a designed questionnaire was distributed among some experts, distributors and retailers and seven independent variables were selected. In this survey, ANFIS sales forecasting technique was employed and MATLAB software was used for data analysis. The results confirmed ANFIS as a good method to predict the product life cycle.

  3. Functional properties of the isomorphic biphasic algal life cycle.

    Science.gov (United States)

    Thornber, Carol S

    2006-10-01

    Many species of marine algae have life cycles that involve multiple separate, free-living phases that frequently differ in ploidy levels. These complex life cycles have received increasing scientific attention over the past few decades, due to their usefulness for both ecological and evolutionary studies. I present a synthesis of our current knowledge of the ecological functioning and evolutionary implications of the isomorphic, biphasic life cycles commonly found in many species of marine algae. There are both costs and benefits to life cycles with 2 morphologically similar but separate, free-living phases that differ in ploidy levels (haploids and diploids). Evolutionary theory predicts that the existence of subtle yet important differences between the phases may be what allows these life cycles to be maintained. Different phases of the same species can vary in abundance, in demographic parameters such as mortality and fecundity, in their physiology, and in their resistance to herbivory. Some taxonomic groups within the red algae have received significant attention toward these issues, while our knowledge of these properties for brown and green algae remains limited.

  4. Ten reasons to exclude viruses from the tree of life.

    Science.gov (United States)

    Moreira, David; López-García, Purificación

    2009-04-01

    When viruses were discovered, they were accepted as missing links between the inert world and living organisms. However, this idea was soon abandoned as information about their molecular parasitic nature accumulated. Recently, the notion that viruses are living organisms that have had a role in the evolution of some essential features of cells has experienced a renaissance owing to the discovery of unusually large and complex viruses that possess typical cellular genes. Here, we contend that there is strong evidence against the notion that viruses are alive and represent ancient lineages of the tree of life.

  5. Geothermal activity helps life survive glacial cycles.

    Science.gov (United States)

    Fraser, Ceridwen I; Terauds, Aleks; Smellie, John; Convey, Peter; Chown, Steven L

    2014-04-15

    Climate change has played a critical role in the evolution and structure of Earth's biodiversity. Geothermal activity, which can maintain ice-free terrain in glaciated regions, provides a tantalizing solution to the question of how diverse life can survive glaciations. No comprehensive assessment of this "geothermal glacial refugia" hypothesis has yet been undertaken, but Antarctica provides a unique setting for doing so. The continent has experienced repeated glaciations that most models indicate blanketed the continent in ice, yet many Antarctic species appear to have evolved in almost total isolation for millions of years, and hence must have persisted in situ throughout. How could terrestrial species have survived extreme glaciation events on the continent? Under a hypothesis of geothermal glacial refugia and subsequent recolonization of nongeothermal regions, we would expect to find greater contemporary diversity close to geothermal sites than in nongeothermal regions, and significant nestedness by distance of this diversity. We used spatial modeling approaches and the most comprehensive, validated terrestrial biodiversity dataset yet created for Antarctica to assess spatial patterns of diversity on the continent. Models clearly support our hypothesis, indicating that geothermally active regions have played a key role in structuring biodiversity patterns in Antarctica. These results provide critical insights into the evolutionary importance of geothermal refugia and the history of Antarctic species.

  6. Geothermal activity helps life survive glacial cycles

    Science.gov (United States)

    Fraser, Ceridwen I.; Terauds, Aleks; Smellie, John; Convey, Peter; Chown, Steven L.

    2014-01-01

    Climate change has played a critical role in the evolution and structure of Earth’s biodiversity. Geothermal activity, which can maintain ice-free terrain in glaciated regions, provides a tantalizing solution to the question of how diverse life can survive glaciations. No comprehensive assessment of this “geothermal glacial refugia” hypothesis has yet been undertaken, but Antarctica provides a unique setting for doing so. The continent has experienced repeated glaciations that most models indicate blanketed the continent in ice, yet many Antarctic species appear to have evolved in almost total isolation for millions of years, and hence must have persisted in situ throughout. How could terrestrial species have survived extreme glaciation events on the continent? Under a hypothesis of geothermal glacial refugia and subsequent recolonization of nongeothermal regions, we would expect to find greater contemporary diversity close to geothermal sites than in nongeothermal regions, and significant nestedness by distance of this diversity. We used spatial modeling approaches and the most comprehensive, validated terrestrial biodiversity dataset yet created for Antarctica to assess spatial patterns of diversity on the continent. Models clearly support our hypothesis, indicating that geothermally active regions have played a key role in structuring biodiversity patterns in Antarctica. These results provide critical insights into the evolutionary importance of geothermal refugia and the history of Antarctic species. PMID:24616489

  7. Life cycle assessment and life cycle costs for pre-disaster waste management systems.

    Science.gov (United States)

    Wakabayashi, Yohei; Peii, Tsai; Tabata, Tomohiro; Saeki, Takashi

    2017-10-01

    This study develops a method of environmental and economic evaluation of an integrated disaster waste management system that considers the spatial scale of removal, transport, and treatment of disaster waste. A case study was conducted on combustibles, which is a type of disaster waste derived from dwellings, in Mie Prefecture, Japan. First, we calculated the quantity and the spatial distribution of disaster waste derived from dwellings and tsunami debris produced as a result of a large-scale earthquake. The quantity of disaster waste was estimated as 7,178,000t with functioning flood-preventing facilities and 11,956,000t without functioning flood prevention facilities. Ensuring resilience in the face of earthquakes and tsunamis by renovating flood-preventing facilities is extremely important in decreasing the production of wastes, especially in coastal regions. Next, the transportation network for transporting combustibles in disaster waste to temporary storage sites, incineration plants, and landfill was constructed using an optimization model. The results showed that if flood-preventing facilities do not function properly, the installation of temporary incineration facilities becomes essential. Life-cycle emissions of CO 2 , SO x , NO x , and PM and the costs of removal, storage, and treatment of combustibles were calculated as 258,000t, 618t, 1705t, 7.9t, and 246millionUSD, respectively, in the case of functioning flood-preventing facilities. If flood-preventing facilities do not function, the quantity of environmentally unfriendly emissions and the costs increase. This result suggested the significance of renovation in order to maintain the conditions of flood-preventing facilities to decrease the environmental burden and costs as well as keep the production of disaster waste at a minimum. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Phosphate cycling on the basic protein of Plodia interpunctella granulosis virus

    Science.gov (United States)

    Funk, C. J.; Consigli, R. A.; Spooner, B. S. (Principal Investigator)

    1993-01-01

    The presence of infected cell-specific phosphoproteins was investigated in Plodia interpunctella granulosis virus (PiGV)-infected fat body using [32P]orthophosphoric acid labeling. One infected cell-specific phosphoprotein had a mobility similar to that of the basic protein (VP12) of PiGV. Further analysis, using immunoblotting and acid-urea gel analysis of infected fat body, confirmed that this phosphoprotein was VP12. However we did not detect phosphorylated VP12 in 32P-labeled nucleocapsids. Phosphoamino acid analysis of 32P-labeled VP12 revealed that phosphoserine was present in the basic protein. Since VP12 is phosphorylated in the infected cell, but not in the nucleocapsid, it appears that dephosphorylation of VP12 is a critical event in the life cycle of the virus. We therefore assayed virus nucleocapsids and infected fat body for the presence of phosphatase activity. Phosphatase activity was not detected in the virus, but the infected fat body had more activity than uninfected fat body. A model for nucleocapsid assembly and uncoating is presented which takes into account the phosphorylation state of VP12, the role of Zn2+ in the nucleocapsid, and the role of the capsid-associated kinase.

  9. Life cycle assessment and the agri-food chain

    DEFF Research Database (Denmark)

    Hermansen, John Erik; Nguyen, T Lan T

    2012-01-01

    Our food consumption is responsible for a major part of the environmental impact related to our total consumption. Life cycle assessment (LCA) is a product-oriented tool that can be used efficiently to identify improvement options within the food chain covering a product’s life cycle from cradle...... of resource use and emissions associated with a product’s life cycle can be aggregated into impact categories (e.g., nonrenewable energy use, land occupation, global warming, acidification, etc.) and further aggregated into overall damage impacts (e.g., impacts on biodiversity, human health, and resource...... to grave, which is very complex for many foods, and to support choices of consumption. The LCA methodology is supported by public standards and public policy measures and has proved its value in business development for more environmentally friendly products. It is an essential feature that the effects...

  10. Life Cycle Cost Optimization of a Bolig+ Zero Energy Building

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna

    Buildings consume approximately 40% of the world’s primary energy use. Considering the total energy consumption throughout the whole life cycle of a building, the energyperformance and supply is an important issue in the context of climate change, scarcity of energy resources and reduction......, and if applicable (7) the requirements of the building-grid interaction. Moreover, the studyrevealed that the future ZEB definitions applied in the Denmark should mostly be focused on grid-connected ZEBs – Net ZEBs, and the annual primary energy balance. The Life Cycle Cost (LCC) analysis conducted with a study...... included in the current building code, and ten renewable energy supply systems including both on-site and off-site options. Theresults indicated that although the off-site options have lower life cycle costs than the on-site alternatives, their application would promote renewable technologies overenergy...

  11. Life Cycle Assessment in the Cereal and Derived Products Sector

    DEFF Research Database (Denmark)

    Renzulli, Pietro A.; Bacenetti, Jacopo; Benedetto, Graziella

    2015-01-01

    This chapter discusses the application of life cycle assessment methodologies to rice, wheat, corn and some of their derived products. Cereal product systems are vital for the production of commodities of worldwide importance that entail particular environmental hot spots originating from...... their widespread use and from their particular nature. It is thus important for tools such as life cycle assessment (LCA) to be tailored to such cereal systems in order to be used as a means of identifying the negative environmental effects of cereal products and highlighting possible pathways to overall...... environmental improvement in such systems. Following a brief introduction to the cereal sector and supply chain, this chapter reviews some of the current cereal-based life cycle thinking literature, with a particular emphasis on LCA. Next, an analysis of the LCA methodological issues emerging from...

  12. Implementation of Life Cycle Assessment in Product Development

    DEFF Research Database (Denmark)

    McAloone, Timothy Charles; Hauschild, M.

    2003-01-01

    The overall aim of the paper is to provide an understanding of the environmental issues involved in the early stages of product development and the capacity of life cycle assessment techniques to address these issues. The paper aims to outline the problems for the designer in evaluating......, and of the opportunities for introducing environmental criteria in the design process through meeting the information requirements of the designer on the different life cycle stages, producing an in-depth understanding of the attitudes of practitioners among product developers to the subject area, and an understanding...... of possible future directions for product development. An Environmentally Conscious Design method is introduced and trade-offs are presented between design degrees of freedom and environmental solutions. Life cycle design frameworks and strategies are addressed. The paper collects experiences and ideas around...

  13. Life Cycle Cost Optimization of a BOLIG+ Zero Energy Building

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna

    Buildings consume approximately 40% of the world’s primary energy use. Considering the total energy consumption throughout the whole life cycle of a building, the energy performance and supply is an important issue in the context of climate change, scarcity of energy resources and reduction......, and if applicable (7) the requirements of the building-grid interaction. Moreover, the study revealed that the future ZEB definitions applied in the Denmark should mostly be focused on grid-connected ZEBs – Net ZEBs, and the annual primary energy balance. The Life Cycle Cost (LCC) analysis conducted with a study...... included in the current building code, and ten renewable energy supply systems including both on-site and off-site options. The results indicated that although the off-site options have lower life cycle costs than the on-site alternatives, their application would promote renewable technologies over energy...

  14. Industrial open source solutions for product life cycle management

    Directory of Open Access Journals (Sweden)

    Jaime Campos

    2014-12-01

    Full Text Available The authors go through the open source for product life cycle management (PLM and the efforts done from communities such as the open source initiative. The characteristics of the open source solutions are highlighted as well. Next, the authors go through the requirements for PLM. This is an area where more attention has been given as the manufacturers are competing with the quality and life cycle costs of their products. Especially, the need of companies to try to get a strong position in providing services for their products and thus to make themselves less vulnerable to changes in the market has led to high interest in product life cycle simulation. The potential of applying semantic data management to solve these problems discussed in the light of recent developments. In addition, a basic roadmap is presented as to how the above-described problems could be tackled with open software solutions.

  15. From life cycle assessment to sustainable production: Status and perspectives

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Jeswiet, Jack; Alting, Leo

    2005-01-01

    The paper reviews the current state of Life Cycle Assessment (LCA) introducing the central elements of the methodology and the latest developments in assessment of the environmental, economic and social impacts along the product chain. The central role of LCA in Integrated Product Policy (IPP...... the sustainability challenge to our societies is discussed, and it is concluded that industry must include not only the eco-efficiency but also the product's environmental justification and the company ethics in a life cycle perspective in order to become sustainable. In the outlook it is concluded that current...... to the tools for design for disassembly. Life Cycle Engineering is defined, and a systematic hierarchy is presented for the different levels at which environmental impacts from industry can be addressed by the engineer in order to improve the eco-efficiency of the industry. The role of industry in meeting...

  16. Commissioning tools for life-cycle building performance assurance

    Energy Technology Data Exchange (ETDEWEB)

    Piette, M.A. [Lawrence Berkeley National Lab., CA (United States). Energy and Environment Div.

    1996-05-01

    This paper discusses information systems for building life-cycle performance analysis and the use of computer-based commissioning tools within this context. There are many reasons why buildings do not perform in practice as well as intended at the design stage. One reason is the lack of commissioning. A second reason is that design intent is not well documented, and performance targets for building components and systems are not well specified. Thus, criteria for defining verification and functional tests is unclear. A third reason is that critical information is often lost throughout the building life-cycle, which causes problems such as misunderstanding of operational characteristics and sequences and reduced overall performance. The life-cycle building performance analysis tools project discussed in this paper are focused on chillers and cooling systems.

  17. LIFE Materials: Fuel Cycle and Repository Volume 11

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, H; Blink, J A

    2008-12-12

    The fusion-fission LIFE engine concept provides a path to a sustainable energy future based on safe, carbon-free nuclear power with minimal nuclear waste. The LIFE design ultimately offers many advantages over current and proposed nuclear energy technologies, and could well lead to a true worldwide nuclear energy renaissance. When compared with existing and other proposed future nuclear reactor designs, the LIFE engine exceeds alternatives in the most important measures of proliferation resistance and waste minimization. The engine needs no refueling during its lifetime. It requires no removal of fuel or fissile material generated in the LIFE engine. It leaves no weapons-attractive material at the end of life. Although there is certainly a need for additional work, all indications are that the 'back end' of the fuel cycle does not to raise any 'showstopper' issues for LIFE. Indeed, the LIFE concept has numerous benefits: (1) Per unit of electricity generated, LIFE engines would generate 20-30 times less waste (in terms of mass of heavy metal) requiring disposal in a HLW repository than does the current once-through fuel cycle. (2) Although there may be advanced fuel cycles that can compete with LIFE's low mass flow of heavy metal, all such systems require reprocessing, with attendant proliferation concerns; LIFE engines can do this without enrichment or reprocessing. Moreover, none of the advanced fuel cycles can match the low transuranic content of LIFE waste. (3) The specific thermal power of LIFE waste is initially higher than that of spent LWR fuel. Nevertheless, this higher thermal load can be managed using appropriate engineering features during an interim storage period, and could be accommodated in a Yucca-Mountain-like repository by appropriate 'staging' of the emplacement of waste packages during the operational period of the repository. The planned ventilation rates for Yucca Mountain would be sufficient for LIFE waste

  18. Supercapacitor Degradation Assesment by Power Cycling and Calendar Life Tests

    Directory of Open Access Journals (Sweden)

    Sedlakova Vlasta

    2016-09-01

    Full Text Available Degradation of Supercapacitors (SC is quantified by accelerated ageing tests. Energy cycling tests and calendar life tests are used since they address the real operating modes. The periodic characterization is used to analyse evolution of the SC parameters as a whole, and its Helmholtz and diffusion capacitances. These parameters are determined before the ageing tests and during 3 × 105 cycles of both 75% and 100% energy cycling, respectively. Precise evaluation of the capacitance and Equivalent Series Resistance (ESR is based on fitting the experimental data by an exponential function of voltage vs. time. The ESR increases linearly with the number (No of cycles for both 75% and 100% energy cycling, whereas a super-linear increase of ESR vs. time of cycling is observed for the 100% energy cycling. A decrease of capacitance in time had been evaluated for 2000 hours of ageing of SC. A relative change of capacitance is ΔC/C0 = 16% for the 75% energy cycling test and ΔC/C0 = 20% for the 100% energy cycling test at temperature 25°C, while ΔC/C0 = 6% for the calendar test at temperature 22°C for a voltage bias V = 1.0 Vop. The energy cycling causes a greater decrease of capacitance in comparison with the calendar test; such results may be a consequence of increasing the temperature due to the Joule heat created in the SC structure. The charge/discharge current value is the same for both 75% and 100% energy cycling tests, so it is the Joule heat created on both the equivalent series resistance and time-dependent diffuse resistance that should be the source of degradation of the SC structure. The diffuse resistance reaches a value of up to 30Ω within each 75% energy cycle and up to about 43Ω within each 100% energy cycle.

  19. Improving Life-Cycle Cost Management of Spacecraft Missions

    Science.gov (United States)

    Clardy, Dennon

    2010-01-01

    This presentation will explore the results of a recent NASA Life-Cycle Cost study and how project managers can use the findings and recommendations to improve planning and coordination early in the formulation cycle and avoid common pitfalls resulting in cost overruns. The typical NASA space science mission will exceed both the initial estimated and the confirmed life-cycle costs by the end of the mission. In a fixed-budget environment, these overruns translate to delays in starting or launching future missions, or in the worst case can lead to cancelled missions. Some of these overruns are due to issues outside the control of the project; others are due to the unpredictable problems (unknown unknowns) that can affect any development project. However, a recent study of life-cycle cost growth by the Discovery and New Frontiers Program Office identified a number of areas that are within the scope of project management to address. The study also found that the majority of the underlying causes for cost overruns are embedded in the project approach during the formulation and early design phases, but the actual impacts typically are not experienced until late in the project life cycle. Thus, project management focus in key areas such as integrated schedule development, management structure and contractor communications processes, heritage and technology assumptions, and operations planning, can be used to validate initial cost assumptions and set in place management processes to avoid the common pitfalls resulting in cost overruns.

  20. Life Cycle Assessment of the wind farm alpha ventus

    Directory of Open Access Journals (Sweden)

    Wagner H.-J.

    2013-06-01

    Full Text Available Life Cycle Assessments (LCA is an important tool for industry and policy makers, used to determine the actual emissions of a product or technology throughout its whole life cycle. In case of energy production systems or power plants, analysis of energy required to produce the materials and processes; emissions resulting from various processes for materials production and processes resulting into their Cumulated Energy Demand (CED and Global Warming Potential (GWP become important parameters when making decisions on further research, development and deployment of any technology. The method of carrying out such analysis is explained through a case study.

  1. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 4, Activity Analysis-The Methods describes the techniques and concepts for carrying out activity analysis within the systems development life-cycle. Reference is made to the deliverables of data analysis and more than one method of analysis, each a viable alternative to the other, are discussed. The """"bottom-up"""" and """"top-down"""" methods are highlighted. Comprised of seven chapters, this book illustrates how dependent data and activities are on each other. This point is especially brought home when the task of inventing new busin

  2. Analyzing the scheduling system stage of production system life cycle

    Directory of Open Access Journals (Sweden)

    Rajesh Attri

    2015-05-01

    Full Text Available The main objective of this paper is to identify and understand the relationship dynamics among the quality enabled factors affecting the scheduling stage of production system life cycle. For this purpose, Interpretative structural modelling (ISM approach has been utilized for developing the relationships among the various factors of the scheduling system stage. Afterwards, MICMAC (Matriced Impacts Croises Multiplication Appliqueeaun Classement analysis has been carried out in order to classify the factors into different categories and to disclose the direct and indirect effects of each factor on the scheduling system. It is an approach for refining the decision making in the scheduling stage of production system life cycle.

  3. Research on conceptual/innovative design for the life cycle

    Science.gov (United States)

    Cagan, Jonathan; Agogino, Alice M.

    1990-01-01

    The goal of this research is developing and integrating qualitative and quantitative methods for life cycle design. The definition of the problem includes formal computer-based methods limited to final detailing stages of design; CAD data bases do not capture design intent or design history; and life cycle issues were ignored during early stages of design. Viewgraphs outline research in conceptual design; the SYMON (SYmbolic MONotonicity analyzer) algorithm; multistart vector quantization optimization algorithm; intelligent manufacturing: IDES - Influence Diagram Architecture; and 1st PRINCE (FIRST PRINciple Computational Evaluator).

  4. The data life cycle applied to our own data.

    Science.gov (United States)

    Goben, Abigail; Raszewski, Rebecca

    2015-01-01

    Increased demand for data-driven decision making is driving the need for librarians to be facile with the data life cycle. This case study follows the migration of reference desk statistics from handwritten to digital format. This shift presented two opportunities: first, the availability of a nonsensitive data set to improve the librarians' understanding of data-management and statistical analysis skills, and second, the use of analytics to directly inform staffing decisions and departmental strategic goals. By working through each step of the data life cycle, library faculty explored data gathering, storage, sharing, and analysis questions.

  5. Life-cycle analysis of product integrated polymer solar cells

    DEFF Research Database (Denmark)

    Espinosa Martinez, Nieves; García-Valverde, Rafael; Krebs, Frederik C

    2011-01-01

    A life cycle analysis (LCA) on a product integrated polymer solar module is carried out in this study. These assessments are well-known to be useful in developmental stages of a product in order to identify the bottlenecks for the up-scaling in its production phase for several aspects spanning from......, switch and a white light emitting semiconductor diode. The polymer solar cell employed in this prototype presents a power conversion efficiency in the range of 2 to 3% yielding energy payback times (EPBT) in the range of 1.3–2 years. Based on this it is worthwhile to undertake a life-cycle study...

  6. Life cycle assessments of energy from solid waste

    Energy Technology Data Exchange (ETDEWEB)

    Finnveden, Goeran; Johansson, Jessica; Lind, Per; Moberg, Aasa [Stockholm Univ. (Sweden). Dept. of Systems Ecology/Natural Resoruces Management Inst.]|[Defence Research Establishment, Stockholm (Sweden). Div. of Defence Analysis

    2000-09-01

    The overall aim of the present study is to evaluate different strategies for treatment of solid waste based on a life-cycle perspective. Important goals are to identify advantages and disadvantages of different methods for treatment of solid waste, and to identify critical factors in the systems, including the background systems, which may significantly influence the results. Included in the study are landfilling, incineration, recycling, digestion and composting. The waste fractions considered are the combustible and recyclable or compostable fractions of municipal solid waste. The methodology used is Life Cycle Assessment. The results can be used for policy decisions as well as strategic decisions on waste management systems.

  7. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle: Book 2, Data Analysis-The Methods describes the methods for carrying out data analysis within the systems development life-cycle and demonstrates how the results of fact gathering can be used to produce and verify the analysis deliverables. A number of alternative methods of analysis other than normalization are suggested. Comprised of seven chapters, this book shows the tasks to be carried out in the logical order of progression-preparation, collection, analysis of the existing system (which comprises the tasks of synthesis, verification, an

  8. Research on large equipment maintenance system in life cycle

    Science.gov (United States)

    Xu, Xiaowei; Wang, Hongxia; Liu, Zhenxing; Zhang, Nan

    2017-06-01

    In order to change the current disadvantages of traditional large equipment maintenance concept, this article plans to apply the technical method of prognostics and health management to optimize equipment maintenance strategy and develop large equipment maintenance system. Combined with the maintenance procedures of various phases in life cycle, it concluded the formulation methods of maintenance program and implement plans of maintenance work. In the meantime, it takes account into the example of the dredger power system of the Waterway Bureau to establish the auxiliary platform of ship maintenance system in life cycle.

  9. Early-Life Origins of Life-Cycle Well-Being: Research and Policy Implications

    Science.gov (United States)

    Currie, Janet; Rossin-Slater, Maya

    2015-01-01

    Mounting evidence across different disciplines suggests that early-life conditions can have consequences on individual outcomes throughout the life cycle. Relative to other developed countries, the United States fares poorly on standard indicators of early-life health, and this disadvantage may have profound consequences not only for population…

  10. [Intercultural health: The life cycle stages in the Andes].

    Science.gov (United States)

    María, Luis Alberto Santa

    2017-01-01

    The most relevant theories and ideas about the life cycle in the Andes and their relationship with human development and health are presented. The life cycle is not an immutable phenomenon, the number of stages and its meaning is historically and culturally based. A comparative analysis with the theory of Freud and Erikson was made. It is concluded that the contribution of Andean culture focuses on: 1) Each stage of human development is associated with productive and reproductive processes of life in relation, as well as an adequate balance between rights and duties in life in society; 2) The couple is the basic social unit, and not the individual. It is a contribution to the design of health interventions with an intercultural approach.

  11. Evidence that life history characteristics of wild birds influence infection and exposure to influenza A viruses.

    Science.gov (United States)

    Ely, Craig R; Hall, Jeffrey S; Schmutz, Joel A; Pearce, John M; Terenzi, John; Sedinger, James S; Ip, Hon S

    2013-01-01

    We report on life history characteristics, temporal, and age-related effects influencing the frequency of occurrence of avian influenza (AI) viruses in four species of migratory geese breeding on the Yukon-Kuskokwim Delta, Alaska. Emperor geese (Chen canagica), cackling geese (Branta hutchinsii), greater white-fronted geese (Anser albifrons), and black brant (Branta bernicla), were all tested for active infection of AI viruses upon arrival in early May, during nesting in June, and while molting in July and August, 2006-2010 (n = 14,323). Additionally, prior exposure to AI viruses was assessed via prevalence of antibodies from sera samples collected during late summer in 2009 and 2010. Results suggest that geese are uncommonly infected by low pathogenic AI viruses while in Alaska. The percent of birds actively shedding AI viruses varied annually, and was highest in 2006 and 2010 (1-3%) and lowest in 2007, 2008, and 2009 (viruses, as indicated by high levels of seroprevalence during late summer (47%-96% across species; n = 541). Seroprevalence was >95% for emperor geese, a species that spends part of its life cycle in Asia and is endemic to Alaska and the Bering Sea region, compared to 40-60% for the other three species, whose entire life cycles are within the western hemisphere. Birds viruses, although antibodies were detected in samples from 5-week old birds in 2009. Seroprevalence of known age black brant revealed that no birds <4 years old had seroconverted, compared to 49% of birds ≥4 years of age.

  12. HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis

    Directory of Open Access Journals (Sweden)

    Regina Medvedev

    2016-01-01

    Full Text Available HCV (hepatitis C virus is a member of the Flaviviridae family that contains a single-stranded positive-sense RNA genome of approximately 9600 bases. HCV is a major causative agent for chronic liver diseases such as steatosis, fibrosis, cirrhosis, and hepatocellular carcinoma which are caused by multifactorial processes. Elevated levels of reactive oxygen species (ROS are considered as a major factor contributing to HCV-associated pathogenesis. This review summarizes the mechanisms involved in formation of ROS in HCV replicating cells and describes the interference of HCV with ROS detoxifying systems. The relevance of ROS for HCV-associated pathogenesis is reviewed with a focus on the interference of elevated ROS levels with processes controlling liver regeneration. The overview about the impact of ROS for the viral life cycle is focused on the relevance of autophagy for the HCV life cycle and the crosstalk between HCV, elevated ROS levels, and the induction of autophagy.

  13. Indicators for human toxicity in Life Cycle Impact Assessment

    DEFF Research Database (Denmark)

    Krewitt, Wolfram; Pennington, David W.; Olsen, Stig Irving

    2002-01-01

    The main objectives of this task group under SETAC-Europe’s Second Working Group on Life Cycle Impact Assessment (LCIA-WIA2) were to identify and discuss the suitability of toxicological impact measures for human health for use in characterization in LCIA. The current state of the art of defining......, as well as potency. Quantitative severity-based indicators yield measures in terms of Years of Life Lost (YOLL), Disability Adjusted Life Years (DALY), Quality Adjusted Life Years (QALY) and other similar measures. DALYs and QALYs are examples of approaches that attempt to account for both years of life...... lost (mortality) and years of impaired life (morbidity). Qualitative severity approaches tend to arrange potency-based indicators in categories, avoiding the need to quantitatively express differences in severity. Based on the proposed criteria and current state of the knowledge, toxicological potency...

  14. 7 CFR 2902.8 - Determining life cycle costs, environmental and health benefits, and performance.

    Science.gov (United States)

    2010-01-01

    ... DESIGNATING BIOBASED PRODUCTS FOR FEDERAL PROCUREMENT General § 2902.8 Determining life cycle costs... products, and will provide the life cycle assessment and life cycle cost information Federal agencies might... 7 Agriculture 15 2010-01-01 2010-01-01 false Determining life cycle costs, environmental and...

  15. A Robust Hybrid Zn-Battery with Ultralong Cycle Life.

    Science.gov (United States)

    Li, Bing; Quan, Junye; Loh, Adeline; Chai, Jianwei; Chen, Ye; Tan, Chaoliang; Ge, Xiaoming; Hor, T S Andy; Liu, Zhaolin; Zhang, Hua; Zong, Yun

    2017-01-11

    Advanced batteries with long cycle life and capable of harnessing more energies from multiple electrochemical reactions are both fundamentally interesting and practically attractive. Herein, we report a robust hybrid zinc-battery that makes use of transition-metal-based redox reaction (M-O-OH → M-O, M = Ni and Co) and oxygen reduction reaction (ORR) to deliver more electrochemical energies of comparably higher voltage with much longer cycle life. The hybrid battery was constructed using an integrated electrode of NiCo 2 O 4 nanowire arrays grown on carbon-coated nickel foam, coupled with a zinc plate anode in alkaline electrolyte. Benefitted from the M-O/M-O-OH redox reactions and rich ORR active sites in NiCo 2 O 4 , the battery has concurrently exhibited high working voltage (by M-O-OH → M-O) and high energy density (by ORR). The good oxygen evolution reaction (OER) activity of the electrode and the reversible M-O ↔ M-O-OH reactions also enabled smooth recharging of the batteries, leading to excellent cycling stabilities. Impressively, the hybrid batteries maintained highly stable charge-discharge voltage profile under various testing conditions, for example, almost no change was observed over 5000 cycles at a current density of 5 mA cm -2 after some initial stabilization. With merits of higher working voltage, high energy density, and ultralong cycle life, such hybrid batteries promise high potential for practical applications.

  16. The life cycle and life span of Namibian fairy circles.

    Science.gov (United States)

    Tschinkel, Walter R

    2012-01-01

    In Namibia of southwestern Africa, the sparse grasslands that develop on deep sandy soils under rainfall between 50 and 100 mm per annum are punctuated by thousands of quasi-circular bare spots, usually surrounded by a ring of taller grass. The causes of these so-called "fairy circles" are unknown, although a number of hypotheses have been proposed. This paper provides a more complete description of the variation in size, density and attributes of fairy circles in a range of soil types and situations. Circles are not permanent; their vegetative and physical attributes allow them to be arranged into a life history sequence in which circles appear (birth), develop (mature) and become revegetated (die). Occasionally, they also enlarge. The appearance and disappearance of circles was confirmed from satellite images taken 4 years apart (2004, 2008). The frequency of births and deaths as a fraction of the total population of circles allowed the calculation of an approximate turnover rate, and from this, an estimate of circle lifespan. Lifespan appeared to vary with circle size, with small circles averaging about 24 years, and larger ones 43-75 years. Overall lifespan averaged about 41 yr. A second, independent estimate of lifespan was made by revisiting circles 2 to 9 years after their clear status had been confirmed. This resulted in a lifespan estimate of about 60 years. Any causal explanation of fairy circles must include their birth, development and death, their mean lifespan and the variation of their features under different conditions.

  17. Innovative predictive maintenance concepts to improve life cycle management

    NARCIS (Netherlands)

    Tinga, Tiedo

    2014-01-01

    For naval systems with typically long service lives, high sustainment costs and strict availability requirements, an effective and efficient life cycle management process is very important. In this paper four approaches are discussed to improve that process: physics of failure based predictive

  18. Confronting Uncertainty in Life Cycle Assessment Used for Decision Support

    DEFF Research Database (Denmark)

    Herrmann, Ivan Tengbjerg; Hauschild, Michael Zwicky; Sohn, Michael D.

    2014-01-01

    The aim of this article is to help confront uncertainty in life cycle assessments (LCAs) used for decision support. LCAs offer a quantitative approach to assess environmental effects of products, technologies, and services and are conducted by an LCA practitioner or analyst (AN) to support...

  19. Life Cycle Assessment Software for Product and Process Sustainability Analysis

    Science.gov (United States)

    Vervaeke, Marina

    2012-01-01

    In recent years, life cycle assessment (LCA), a methodology for assessment of environmental impacts of products and services, has become increasingly important. This methodology is applied by decision makers in industry and policy, product developers, environmental managers, and other non-LCA specialists working on environmental issues in a wide…

  20. Life cycle impact assessment (LCIA) using the ecological scarcity ...

    African Journals Online (AJOL)

    Life cycle assessment (LCA) is a method use to analyze a product or a service from the beginning of the process where it is extracted until it is not useful anymore or it is known as cradle-to-grave analysis. LCA analysis includes the inventory collecting all types of emission and waste. After it is done, the inventory will be ...

  1. Application of product life cycle concept to private label management

    Directory of Open Access Journals (Sweden)

    Sandra Horvat

    2013-06-01

    Full Text Available Private labels have recorded significant growth rates worldwide, becoming a serious threat to manufacturer brands. Development of private labels in many different product categories increased the complexity of their management. Therefore, this paper examines the possibility of using the product life cycle concept in private label management. Given that private labels are a specific brand type, it is necessary to adjust certain elements of the product life cycle concept, as it was developed on the basis of manufacturer brands. For instance, in the growth stage of the product life cycle, retailers expand private labels to a number of product categories and use the push strategy while manufacturers tend to expand their distribution network in the expansion of their brands and predominantly use the pull strategy in doing so. Furthermore, there is a focus shift from low-price strategy, predominantly used in the introduction phase, to increasing the quality and private label value in the later stages of the product life cycle.

  2. Applying life cycle management of colombian cocoa production

    Directory of Open Access Journals (Sweden)

    Oscar Orlando Ortiz-R

    2014-03-01

    Full Text Available The present research aims to evaluate the usefulness of the application of Life Cycle Management in the agricultural sector focusing on the environmental and socio-economic aspects of decision making in the Colombian cocoa production. Such appraisal is based on the application of two methodological tools: Life Cycle Assessment, which considers environmental impacts throughout the life cycle of the cocoa production system, and Taguchi Loss Function, which measures the economic impact of a process' deviation from production targets. Results show that appropriate improvements in farming practices and supply consumption can enhance decision-making in the agricultural cocoa sector towards sustainability. In terms of agri-business purposes, such qualitative shift allows not only meeting consumer demands for environmentally friendly products, but also increasing the productivity and competitiveness of cocoa production, all of which has helped Life Cycle Management gain global acceptance. Since farmers have an important role in improving social and economic indicators at the national level, more attention should be paid to the upgrading of their cropping practices. Finally, one fundamental aspect of national cocoa production is the institutional and governmental support available for farmers in face of socio-economic or technological needs.

  3. Marktorientiertes Kostenmanagement durch Target Costing und Product Life Cycle Costing

    OpenAIRE

    Fischer, Thomas

    1997-01-01

    Marktorientiertes Kostenmanagement durch Target Costing und Product Life Cycle Costing / Adolf G. Coenenberg ; Thomas M. Fischer ; Jochen Schmitz. - In: Marktorientierte Unternehmensführung : Festschr. für Heribert Meffert zum 60. Geburtstag / hrsg. von Manfred Bruhn ... - 2., aktualis. Aufl. - Wiesbaden : Gabler, 1998. - S. 372-402 [1. Aufl. 1997

  4. Environmental life cycle assessments for water treatment processes ...

    African Journals Online (AJOL)

    The objective of this study was to generate information on the environmental profile of the life cycle of water, including treatment, distribution and collection and disposal (including recycling), in an urban context. As a case study the eThekwini Municipality (with its main city Durban) in South Africa was used. Another aim of ...

  5. LIFE CYCLE DESIGN OF IN-MOLD SURFACING FILM

    Science.gov (United States)

    Since 1990, the NRMRL has been at the forefront in the development of Life Cycle Assessment as a methodology for environmental assessment. In 1994, NRMRL established an LCA Team to organize individual efforts into a comprehensive research program. The LCA Team coordinates work in...

  6. Life cycle impact assssment of biobased plastics from sugarcane ethanol

    NARCIS (Netherlands)

    Tsiropoulos, Ioannis; Faaij, André; Lundquist, Lars; Schenker, Urs; Biois, J.F.; Patel, M.K.

    The increasing production of bio-based plastics calls for thorough environmental assessments. Using life cycle assessment, this study compares European supply of fully bio-based high-density polyethylene and partially bio-based polyethylene terephthalate from Brazilian and Indian sugarcane ethanol

  7. Life Cycle Impact Assessment: Striving towards best practice

    DEFF Research Database (Denmark)

    Udo de Haes, H.A.; Finnveden, G; Goedkoop, M

    2002-01-01

    The publication focuses on furthering the development of a technical framework, offers an overview of existing data and methods for different impact categories and explores evaluation criteria, including scientific validity, transparency, environmental relevance, feasibility and links with life......-cycle inventory....

  8. Pets, Attachment, and Well-Being across the Life Cycle.

    Science.gov (United States)

    Sable, Pat

    1995-01-01

    Using an ethological framework, explores the ways in which family pets, in particular dogs and cats, provide certain components of attachment that contribute to emotional and social well-being throughout the life cycle. Implications are identified for social policies that will protect and maintain this bond for particular populations. (RJM)

  9. Life cycle assessment Part 2 : Current impact assessment practice

    NARCIS (Netherlands)

    Pennington, D.W; Potting, J; Finnveden, G; Lindeijer, E; Jolliet, O; Rydberg, T.; Rebitzer, G.

    Providing our society with goods and services contributes to a wide range of environmental impacts. Waste generation, emissions and the consumption of resources occur at many stages in a product's life cycle-from raw material extraction, energy acquisition, production and manufacturing, use, reuse,

  10. Bridging Arctic environmental science and life cycle assessment

    DEFF Research Database (Denmark)

    Johnsen, Fredrik Moltu

    2014-01-01

    Current research aims to make the impact assessment module of life cycle assessment (LCA) less site-generic and thus more relevant to particular regions. The Arctic region attracts its share of interest when it comes to environmental issues, but little research has been performed with the explicit...

  11. Sustainability metrics: life cycle assessment and green design in polymers.

    Science.gov (United States)

    Tabone, Michaelangelo D; Cregg, James J; Beckman, Eric J; Landis, Amy E

    2010-11-01

    This study evaluates the efficacy of green design principles such as the "12 Principles of Green Chemistry," and the "12 Principles of Green Engineering" with respect to environmental impacts found using life cycle assessment (LCA) methodology. A case study of 12 polymers is presented, seven derived from petroleum, four derived from biological sources, and one derived from both. The environmental impacts of each polymer's production are assessed using LCA methodology standardized by the International Organization for Standardization (ISO). Each polymer is also assessed for its adherence to green design principles using metrics generated specifically for this paper. Metrics include atom economy, mass from renewable sources, biodegradability, percent recycled, distance of furthest feedstock, price, life cycle health hazards and life cycle energy use. A decision matrix is used to generate single value metrics for each polymer evaluating either adherence to green design principles or life-cycle environmental impacts. Results from this study show a qualified positive correlation between adherence to green design principles and a reduction of the environmental impacts of production. The qualification results from a disparity between biopolymers and petroleum polymers. While biopolymers rank highly in terms of green design, they exhibit relatively large environmental impacts from production. Biopolymers rank 1, 2, 3, and 4 based on green design metrics; however they rank in the middle of the LCA rankings. Polyolefins rank 1, 2, and 3 in the LCA rankings, whereas complex polymers, such as PET, PVC, and PC place at the bottom of both ranking systems.

  12. sensitivity analysis on flexible road pavement life cycle cost model

    African Journals Online (AJOL)

    Sensitivity analysis is a tool used in the assessment of a model's performance. This study examined the application of sensitivity analysis on a developed flexible pavement life cycle cost model using varying discount rate. The study area is Effurun, Uvwie Local Government Area of Delta State of Nigeria. In order to ...

  13. Transport biofuels - a life-cycle assessment approach

    NARCIS (Netherlands)

    Reijnders, L.

    2008-01-01

    Life-cycle studies of the currently dominant transport biofuels (bioethanol made from starch or sugar and biodiesel made from vegetable oil) show that solar energy conversion efficiency is relatively poor if compared with solar cells and that such biofuels tend to do worse than conventional fossil

  14. Guidance on Data Quality Assessment for Life Cycle Inventory Data

    Science.gov (United States)

    Data quality within Life Cycle Assessment (LCA) is a significant issue for the future support and development of LCA as a decision support tool and its wider adoption within industry. In response to current data quality standards such as the ISO 14000 series, various entities wit...

  15. Refined life-cycle assessment of polymer solar cells

    DEFF Research Database (Denmark)

    Lenzmann, F.; Kroon, J.; Andriessen, R.

    2011-01-01

    A refined life-cycle assessment of polymer solar cells is presented with a focus on critical components, i.e. the transparent conductive ITO layer and the encapsulation components. This present analysis gives a comprehensive sketch of the full environmental potential of polymer-OPV in comparison...

  16. Life cycle assessment of polysaccharide materials: a review

    NARCIS (Netherlands)

    Shen, L.|info:eu-repo/dai/nl/310872022; Patel, M.K.|info:eu-repo/dai/nl/18988097X

    2008-01-01

    Apart from conventional uses of polysaccharide materials, such as food, clothing, paper packaging and construction, new polysaccharide products and materials have been developed. This paper reviews life cycle assessment (LCA) studies in order to gain insight of the environmental profiles of

  17. Reverse logistics network design: a holistic life cycle approach

    National Research Council Canada - National Science Library

    Daaboul, Joanna; Le Duigou, Julien; Penciuc, Diana; Eynard, Benoît

    2014-01-01

    .... This article addresses the issue of designing the reverse logistics network assuring the needed volume of recycled aluminum for the production of L-shaped front lower control arms for personal cars. It details the developed method and demonstrator for designing a reverse logistics network based on a life cycle assessment.

  18. Cost estimation and management over the life cycle of metallurgical ...

    African Journals Online (AJOL)

    Project life cycles, techniques of cost estimation and cost management are examined. A survey was used to gather information by means of face-to-face and telephonic interviews, as well as an electronic questionnaire. The total population of entities in South Africa that conduct metallurgical research projects is small, ...

  19. An introduction to Life-cycle Thinking and Management

    DEFF Research Database (Denmark)

    Remmen, Arne

    This booklet descibes how enterprises can begin developing cleaner products based on a life-cycle perspective. It focuses on a simple approach to preventive environmental initiatives, where enterprises can begin at a level that matches their ambitions and their preconditions. The report is aimed ...

  20. Role of phytolectin in the life cycle of plants

    Directory of Open Access Journals (Sweden)

    Melnykova N. M.

    2012-06-01

    Full Text Available In the review the basic properties of plant lectins and their physiological role in the life cycle of plants are considered. There are data on the current state of the researches of phytolectins and lectin-like proteins as well as designation of the main directions of further study on the functioning of these proteins in the plant physiological processes.

  1. The Importance of Sample Attrition in Life Cycle Labor Supply

    NARCIS (Netherlands)

    Ziliak, J.P.; Kniesner, T.J.

    1996-01-01

    We examine the importance of possible non-random attrition to an econometric model of life cycle labor supply including joint nonlinear taxation of wage and interest incomes and latent heterogeneity.We use a Wald test comparing attriters to nonattriters and variable addition testing based on formal

  2. Site-dependent life-cycle impact assessment of acidification

    DEFF Research Database (Denmark)

    Potting, Josepha Maria Barbara; Schöpp, W.; Blok, Kornelis

    1998-01-01

    for acidification, eutrophication via air; and tropospheric ozone formation. The application of the acidification factors in LCIA is very straightforward. The only additional data required, the geographical site of the emission, is generally provided by current life-cycle inventory analysis. The acidification...... suitable for establishing similar factors for eutrophication and tropospheric ozone formation for regions outside Europe as well....

  3. Life cycle impacts of North American wood panel Manufacturing

    Science.gov (United States)

    Richard Bergman; D. Kaestner; A. M. Taylor

    2016-01-01

    Manufacturing building products such as wood panels impacts the environment, including contributing to climate change. This study is a compilation of four studies quantifying these impacts using the life cycle assessment (LCA) method on five wood-based panel products made in North America during 2012. LCA is an internationally accepted and standardized method for...

  4. Life Cycle of the Oriental Compost Worm Perionyx Excavatus ...

    African Journals Online (AJOL)

    In order to exploit the concept of using vermiculture as biotechnology for waste control and protein production, the life cycle of the vermicomposting species, Perionyx excavatus, was studied. The development, growth and reproduction of P. excavatus were investigated. Urine free cattle manure with a moisture content of ...

  5. Life cycle of the oriental compost worm Perionyx excavatus ...

    African Journals Online (AJOL)

    1989-03-21

    Mar 21, 1989 ... In order to exploit the concept of using vermiculture as biotechnology for waste control and protein production, the life cycle of the vermicomposting species, Perionyx excavatus, was studied. The development, growth and reproduction of P. excavatus were investigated. Urine free cattle manure with a.

  6. Comparative Life-Cycle Cost Analysis Of Solar Photovoltaic Power ...

    African Journals Online (AJOL)

    Many homes in Nigeria are in remote locations where grid electricity supply could not be extended. This paper attempts to present a concise life-cycle-cost comparison of diesel generator power supply system and photovoltaic power system for a remote rural application. In this comparative analysis, conceptual designs ...

  7. Studies on the life cycle and morphometrics of honeybees, Apis ...

    African Journals Online (AJOL)

    The life cycle of the honeybee, Apis mellifera adansonii, was studied in mangrove area by monitoring the developmental stages and morphology of the castes. It was observed that the fate of the eggs were predetermined at the onset leading to drones, queens or workers. It was also established that the three different castes ...

  8. A life-cycle model with ambiguous survival beliefs

    NARCIS (Netherlands)

    Groneck, Max; Ludwig, Alexander; Zimper, Alexander

    Based on a cognitive notion of neo-additive capacities reflecting likelihood insensitivity with respect to survival chances, we construct a Choquet Bayesian learning model over the life-cycle that generates a motivational notion of neo-additive survival beliefs expressing ambiguity attitudes. We

  9. Aircraft bi-level life cycle cost estimation

    NARCIS (Netherlands)

    Zhao, X.; Verhagen, W.J.C.; Curan, R.

    2015-01-01

    n an integrated aircraft design and analysis practice, Life Cycle Cost (LCC) is essential for decision making. The LCC of an aircraft is ordinarily partially estimated by emphasizing a specific cost type. However, an overview of the LCC including design and development cost, production cost,

  10. Normalisation and weighting in life cycle assessment: quo vadis?

    DEFF Research Database (Denmark)

    Pizzol, Massimo; Laurent, Alexis; Sala, Serenella

    2017-01-01

    Purpose: Building on the rhetoric question “quo vadis?” (literally “Where are you going?”), this article critically investigates the state of the art of normalisation and weighting approaches within life cycle assessment. It aims at identifying purposes, current practises, pros and cons, as well...

  11. Life-Cycle Costing for Training System Procurement.

    Science.gov (United States)

    Roden, Steve L.

    1984-01-01

    Discusses annual cost and present worth methods as two basic ways of calculating life-cycle cost to make purchasing decisions when replacing training systems. A training cost analysis worksheet to aid in asking comprehensive questions about training costs as they currently exist is included. (MBR)

  12. Monte Carlo simulation by computer for life-cycle costing

    Science.gov (United States)

    Gralow, F. H.; Larson, W. J.

    1969-01-01

    Prediction of behavior and support requirements during the entire life cycle of a system enables accurate cost estimates by using the Monte Carlo simulation by computer. The system reduces the ultimate cost to the procuring agency because it takes into consideration the costs of initial procurement, operation, and maintenance.

  13. Revisiting the life cycle of dung fungi, Including Sordaria fimicola

    Science.gov (United States)

    George Newcombe; Jason Campbell; David Griffith; Melissa Baynes; Karen Launchbaugh; Rosemary Pendleton

    2016-01-01

    Dung fungi, such as Sordaria fimicola, generally reproduce sexually with ascospores discharged from mammalian dung after passage through herbivores. Their life cycle is thought to be obligate to dung, and thus their ascospores in Quaternary sediments have been interpreted as evidence of past mammalian herbivore activity. Reports of dung fungi as endophytes would seem...

  14. Advancing life cycle economics in the Nordic countries

    DEFF Research Database (Denmark)

    Haugbølle, Kim; Hansen, Ernst Jan de Place

    2005-01-01

    Advancing construction and facilities management requires the ability to estimate and evaluate the economic consequences of decisions in a lifetime perspective. A survey of state-of-the-art on life cycle economics in the Nordic countries showed that, despite a number of similarities, no strong...

  15. Life-cycle of the European compost worm Dendrobaena veneta ...

    African Journals Online (AJOL)

    1990-06-05

    Jun 5, 1990 ... The life-cycle of Dendrobaena veneta was studied to assess the potential of this species in vermicuhure. The development, growth and reproduction were investigated by rearing worms at 25°C on urine-free cattle manure with a moisture content of 80% over a period of 200 days. It was found that cocoons ...

  16. Observations on the life-cycles and larval morphogenesis of ...

    African Journals Online (AJOL)

    The previously unknown life-cycles of Haemonchus bedfordi, Impalala tuberculata and Longistrongylus sabie parasitic in impala, are recorded. Observations on the morphology of the developmental stages and their habitat of these three nematode species are described. The similarities and differences to closely related ...

  17. Life-cycle of the European compost worm Dendrobaena veneta ...

    African Journals Online (AJOL)

    The life-cycle of Dendrobaena veneta was studied to assess the potential of this species in vermiculture. The development, growth and reproduction were investigated by rearing worms at 25°C on urine-free cattle manure with a moisture content of 80% over a period of 200 days. It was found that cocoons are produced at a ...

  18. Life Cycle Assessment of electricity generation: overview and methodological issues

    DEFF Research Database (Denmark)

    Turconi, Roberto; Boldrin, Alessio; Astrup, Thomas Fruergaard

    Electricity production is currently responsible for a large share of global Greenhouse Gas (GHG), NOx and SO2 emissions, and their related environmental impacts. This study provides a critical review of the status of research on life cycle assessment (LCA) of electricity generation. NREL [1...... of emissions, those were divided among three life cycle phases: fuel provision, operation of the plant and infrastructure. It was possible to estimate typical emission factors for all technologies except for biomass, where methodological and technical aspects result in very variable outcomes. Within...... these ranges, we identified direct emissions at the plant as the main contributor to the total GHG emissions for fossil fuels, with thermal efficiency being the most determining parameter. Nevertheless, with high thermal efficiency fuel provision becomes increasingly important (e.g. natural gas combined cycle...

  19. Life cycle greenhouse gas emissions of anesthetic drugs.

    Science.gov (United States)

    Sherman, Jodi; Le, Cathy; Lamers, Vanessa; Eckelman, Matthew

    2012-05-01

    Anesthesiologists must consider the entire life cycle of drugs in order to include environmental impacts into clinical decisions. In the present study we used life cycle assessment to examine the climate change impacts of 5 anesthetic drugs: sevoflurane, desflurane, isoflurane, nitrous oxide, and propofol. A full cradle-to-grave approach was used, encompassing resource extraction, drug manufacturing, transport to health care facilities, drug delivery to the patient, and disposal or emission to the environment. At each stage of the life cycle, energy, material inputs, and emissions were considered, as well as use-specific impacts of each drug. The 4 inhalation anesthetics are greenhouse gases (GHGs), and so life cycle GHG emissions include waste anesthetic gases vented to the atmosphere and emissions (largely carbon dioxide) that arise from other life cycle stages. Desflurane accounts for the largest life cycle GHG impact among the anesthetic drugs considered here: 15 times that of isoflurane and 20 times that of sevoflurane on a per MAC-hour basis when administered in an O(2)/air admixture. GHG emissions increase significantly for all drugs when administered in an N(2)O/O(2) admixture. For all of the inhalation anesthetics, GHG impacts are dominated by uncontrolled emissions of waste anesthetic gases. GHG impacts of propofol are comparatively quite small, nearly 4 orders of magnitude lower than those of desflurane or nitrous oxide. Unlike the inhaled drugs, the GHG impacts of propofol primarily stem from the electricity required for the syringe pump and not from drug production or direct release to the environment. Our results reiterate previous published data on the GHG effects of these inhaled drugs, while providing a life cycle context. There are several practical environmental impact mitigation strategies. Desflurane and nitrous oxide should be restricted to cases where they may reduce morbidity and mortality over alternative drugs. Clinicians should avoid

  20. Data life cycle: a perspective from the Information Science

    Directory of Open Access Journals (Sweden)

    Ricardo César Gonçalves Sant’Ana

    2016-08-01

    Full Text Available Introduction: Access and use of data as a key factor has been extended to several areas of knowledge of today's society. It’s necessary to develop a new perspective that presents phases and factors involved in these processes, providing an initial analysis structure, allowing the efforts, skills and actions organization related to the data life cycle. Purpose: This article is a proposal for a new look at the data life cycle, that assumes, as a central element, the data itself, supporting itself on the concepts and contributions that Information Science can provide, without giving up the reflections on the role of other key areas such as Computer Science. Methodology: The methodological procedures consisted of bibliographic research and content analysis to describe the phases and factors related to the Data Life Cycle, developing reflections and considerations from context already consolidated in the development of systems that can corroborate the idea of centrality of data. Results: The results describe the phases of: collect, storage, recovery and discard, permeated by transverse factors: privacy, integration, quality, copyright, dissemination and preservation, composing a Data Life Cycle. Conclusions: The current context of the availability of large volumes of data, with great variety and at speeds that provide access in real time, setting the so-called Big Data that requires new concerns about access and use processes of data. The Information Science may offer a new approach, now centered in the data, and contribute to the optimization of Data Life Cycle as a whole, extending bridges between users and the data they need.

  1. The life-cycle hypothesis, fiscal policy and social security

    Directory of Open Access Journals (Sweden)

    Tullio Jappelli

    2005-01-01

    Full Text Available In the early 1950s Modigliani, with Brumberg and Ando, formulated the life-cycletheory of consumption and savings that enjoyed a huge and undisputed success. But, since the early 1980s, the life-cycle theory has increasingly come under attack. One reason is the existence of an important inter-generational transmission of wealth, to be imputed to motives that are exogenous to the life-cycle model. The second reason is the growing evidence that the rich continue to save more than the less fortunate, as Keynes in fact maintained. The third reason is that there is growing evidence that young families in their twenties and thirties save a positive and increasing proportion of their income, which is in sharp contrast with the original version of the life-cycletheory. Finally, a number of empirical works have found that pensioners set aside a high proportion of their income. This requires a rethinking of the life-cycle approach.

  2. Life cycle assessment and additives: state of knowledge

    DEFF Research Database (Denmark)

    Concerns about possible toxic effects from additives/impurities accumulated in globally recycled waste/resources like paper and plastics was one of the main reasons for starting up the EU FP7 Coordination Action project RiskCycle (www.wadef.com/projects/riskcycle). A key aim of the project...... is to identify research needs within this area focusing on both risk assessment (RA) and life cycle assessment (LCA). Besides the sectors on paper and plastics also lubricants, textiles, electronics and leather are included in RiskCycle. On plastics a literature review regarding the state of knowledge...... on additives/impurities in LCA has been performed within RiskCycle. Several inventory databases (LCI data) have been investigated and the result shows that most LCI databases use PlasticsEurope data for plastics production. Most of these data are aggregated and do not include additives. Regarding...

  3. Indonesian residential high rise buildings: A life cycle energy assessment

    Energy Technology Data Exchange (ETDEWEB)

    Utama, Agya; Gheewala, Shabbir H. [The Joint Graduate School of Energy and Environment, King Mongkut' s University of Technology Thonburi, Bangkok (Thailand)

    2009-11-15

    This study evaluates the effect of building envelopes on the life cycle energy consumption of high rise residential buildings in Jakarta, Indonesia. For high rise residential buildings, the enclosures contribute 10-50% of the total building cost, 14-17% of the total material mass and 20-30% of the total heat gain. The direct as well as indirect influence of the envelope materials plays an important role in the life cycle energy consumption of buildings. The initial embodied energy of typical double wall and single wall envelopes for high residential buildings is 79.5 GJ and 76.3 GJ, respectively. Over an assumed life span of 40 years, double walls have better energy performance than single walls, 283 GJ versus 480 GJ, respectively. Material selection, which depends not only on embodied energy but also thermal properties, should, therefore, play a crucial role during the design of buildings. (author)

  4. The quest for extraterrestrial life: what about the viruses?

    Science.gov (United States)

    Griffin, Dale Warren

    2013-01-01

    Recently, viruses have been recognized as the most numerous entities and the primary drivers of evolution on Earth. Historically, viruses have been mostly ignored in the field of astrobiology due to the view that they are not alive in the classical sense and if encountered would not present risk due to their host-specific nature. What we currently know of viruses is that we are most likely to encounter them on other life-bearing planets; that while some are exquisitely host-specific, many viruses can utilize hundreds of different host species; that viruses are known to exist in our planet's most extreme environments; and that while many do not survive long outside their hosts, some can survive for extended periods, especially in the cold. In our quest for extraterrestrial life, we should be looking for viruses; and while any encountered may pose no risk, the possibility of an encounter with a virus capable of accessing multiple cell types exists, and any prospective contact with such an organism should be treated accordingly.

  5. The quest for extraterrestrial life: what about the viruses?

    Science.gov (United States)

    Griffin, Dale Warren

    2013-08-01

    Recently, viruses have been recognized as the most numerous entities and the primary drivers of evolution on Earth. Historically, viruses have been mostly ignored in the field of astrobiology due to the view that they are not alive in the classical sense and if encountered would not present risk due to their host-specific nature. What we currently know of viruses is that we are most likely to encounter them on other life-bearing planets; that while some are exquisitely host-specific, many viruses can utilize hundreds of different host species; that viruses are known to exist in our planet's most extreme environments; and that while many do not survive long outside their hosts, some can survive for extended periods, especially in the cold. In our quest for extraterrestrial life, we should be looking for viruses; and while any encountered may pose no risk, the possibility of an encounter with a virus capable of accessing multiple cell types exists, and any prospective contact with such an organism should be treated accordingly.

  6. The new reports on life cycle of Heterosigma akashiwo (Raphidophyceae)

    Science.gov (United States)

    Kim, J. H.

    2016-02-01

    Heterosigma akashiwo (Hada) Hada (Raphidophyceae) is a noxious bloom-forming algal species that has damaged many fish farms in coastal waters during recent decades. Consequently, many studies focused on the population dynamics of H. akashiwo, while its life cycle was not well studied. In this study, we investigated veiled life cycle of H. akashiwo through culture based method. We cultured eight H. akashiwostrains originated from Korea, Japan, USA under various conditions (water temp., light intensity, salinity, pH). Morphological diversity of cells were observed via light microscopy and scanning electron microscopy. To observe nucleus of living cell, cells were stained with Hoechst and changes of cells in culture were observed through time-lapse. For observation of cysts and their germination process, cysts were isolated from sediment. Different from the previous knowledge, H. akashiwo has only vegetative cell stage and cyst stage, we discovered that H. akashiwo has extra small cell stage and large cell stage. Large cells are much bigger (20-45 µm) than vegetative cells. Large cell formation was resulted from fusion of vegetative cells. Small cells were very small (6.88 ± 0.85 µm), these cell divided from large cell or formed in germination process of cysts rarely. Small cells have lower motility than vegetative cells. These results improved the study of life stages of H. akashiwo and this fundamental investigation provide important new information and improve our understanding of the life cycle of H. akashiwo.

  7. Analysis within the systems development life-cycle

    CERN Document Server

    Rock-Evans, Rosemary

    1987-01-01

    Analysis within the Systems Development Life-Cycle, Book 3: Activity Analysis - The Deliverables provides a comprehensive coverage of the deliverables of activity analysis. The book also details purpose of each deliverable in the context of the next tasks in the systems development cycle (SDC). The text first covers the concept of deliverables and the benefits of making deliverables visible. In the second chapter, the book introduces the main concepts and diagrammatic techniques of activity analysis. The third chapter deals with the important classes or categories of concept, while the fourth

  8. Live Cell Imaging of the Schizosaccharomyces pombe Sexual Life Cycle.

    Science.gov (United States)

    Merlini, Laura; Vjestica, Aleksandar; Dudin, Omaya; Bendezú, Felipe; Martin, Sophie G

    2017-10-03

    The fission yeast Schizosaccharomyces pombe is an invaluable model system for studying the principles that drive sexual differentiation and the meiotic cell division cycle. We describe a simple protocol for microscopic observation of the entire sexual life cycle that can be adapted to focus on specific stages of sexual differentiation. After growth to exponential phase in a nitrogen-rich medium, cell cultures are switched to a nitrogen-deprived medium until the population is enriched for the specific stage of the sexual lifecycle to be studied. Cells are then mounted in easily constructed customized agarose pad chambers for imaging. © 2017 Cold Spring Harbor Laboratory Press.

  9. How can a life cycle inventory parametric model streamline life cycle assessment in the wooden pallet sector?

    DEFF Research Database (Denmark)

    Niero, Monia; Di Felice, Francesco; Ren, Jingzheng

    2014-01-01

    of environmental impact) and end-of-life (avoided impact). This result is driven by two parameters: mass of wood and average distance for transport of wood. Based on the results of the application of the LCI parametric model to the identified products, one parameter-based regression and one multiple non-linear...... regression allowed to define a correlation between the life cycle impact assessment (LCIA) category indicators considered and the most influencing parameters.The definition of LCI parametric model in the wooden pallet sector can effectively be used for calculating the environmental impacts of products......This study discusses the use of parameterization within the life cycle inventory (LCI) in the wooden pallet sector, in order to test the effectiveness of LCI parametric models to calculate the environmental impacts of similar products. Starting from a single case study, the objectives of this paper...

  10. Life Cycle Development of Obesity and Its Determinants

    DEFF Research Database (Denmark)

    Cavaco, Sandra; Eriksson, Tor; Skalli, Ali

    ’s situation at a certain age and a random effects dynamic probit analysis of the individuals’ obesity histories. Key findings are: (i) controlling for parental and childhood factors, health behaviour and socioeconomic status affect country differences in overweight and obesity only marginally, (ii) parents......This paper is concerned with how obesity and some of its determinants develop over individuals’ life cycles. In particular we examine empirically the role and relative importance of early life conditions (parents’ education and socioeconomic status) and individuals’ own education as adults and how...

  11. A system boundary identification method for life cycle assessment

    DEFF Research Database (Denmark)

    Li, Tao; Zhang, Hongchao; Liu, Zhichao

    2014-01-01

    Life cycle assessment (LCA) is a useful tool for quantifying the overall environmental impacts of a product, process, or service. The scientific scope and boundary definition are important to ensure the accuracy of LCA results. Defining the boundary in LCA is difficult and there are no commonly...... of processes considered, and the gradient of the fitting curve trends to zero gradually. According to the threshold rules, a relatively accurate system boundary could be obtained.It is found from this research that the system boundary curve describes the growth of life cycle impact assessment (LCIA) results...... accepted scientific methods yet. The objective of this research is to present a comprehensive discussion of system boundaries in LCA and to develop an appropriate boundary delimitation method.A product system is partitioned into the primary system and interrelated subsystems. The hierarchical relationship...

  12. A Literature review of life cycle assessment for bridge infrastructure

    DEFF Research Database (Denmark)

    Du, Guangli

    2010-01-01

    Currently, the whole world is confronted with great challenges related to environmental issues. As a fundamentalinfrastructure in transport networks, railway bridges are responsible for numerous material and energy consumption throughtheir life cycle, which in turn leads to significant...... environmental burdens. However, present management of railway bridgeinfrastructures is mainly focused on the technical and financial aspects, whereas the environmental assessment is rarely integrated. Life cycle assessment (LCA) is deemed as a systematic method for also assessing the environmental impact...... of products and systems, but its application in railway bridge infrastructures is rare. Very limited literature and research studies are available in this area. In order to incorporate the implementation of LCA into railway bridges and set new design criteria, this article performs an elaborate literature...

  13. Life cycle assessment of offset printed matter with EDIP97

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Hansen, Morten Søes; Hauschild, Michael Zwicky

    2009-01-01

    Existing product life cycle assessment (LCA) studies on offset printed matter all point at paper as the overall dominating cause of environmental impacts. All studies focus on energy consumption and the dominating role of paper is primarily based on the energy-related impact categories global...... warming, acidification and nutrient enrichment. Ecotoxicity and human toxicity, which are related to emissions of chemicals etc., are only included to a limited degree or not at all. In this paper we include the impacts from chemicals emitted during the life cycle of sheet fed offset printed matter....... This is done by making use of some of the newest knowledge about emissions from the production at the printing industry combined with knowledge about the composition of the printing materials used. In cases with available data also upstream emissions from the production of printing materials are included...

  14. Goals of stability evaluation throughout the vaccine life cycle.

    Science.gov (United States)

    Krause, Philip R

    2009-11-01

    Stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. At and after licensure, stability studies on quality attributes (including potency) provide a critical link between marketed and clinically evaluated vaccine product, addressing important regulatory concerns by assuring that product quality is maintained throughout the dating period. During development, stability studies are done to assure product quality and to obtain the data needed to support licensure. Stability studies may also be performed after licensure to assure that product continues to perform as it did pre-licensure, as well as to evaluate the effect on product quality of deliberately introduced manufacturing changes. At each phase in the product life cycle, it is important to consider the goals of stability evaluation and to perform appropriate statistical analyses in order to assure and reach appropriate conclusions about product quality.

  15. Life cycle assessment of sewage sludge management: A review

    DEFF Research Database (Denmark)

    Yoshida, Hiroko; Christensen, Thomas Højlund; Scheutz, Charlotte

    2013-01-01

    In this article, 35 published studies on life cycle assessment (LCA) of sewage sludge were reviewed for their methodological and technological assumptions. Overall, LCA has been providing a flexible framework to quantify environmental impacts of wastewater and sewage sludge treatment and disposal...... by the methodological development of the life cycle impact assessment (LCIA) and the advancement of research in quantifying environmental emissions associated with wastewater and sewage sludge treatment processes. Thus, large discrepancies were found in the selection of the environmental emissions to be included...... processes for multiple scales, ranging from process selection to policy evaluation. The results of LCA are, in principle, unique to the goal and scope of each study, reflecting its local conditions and comparison between different LCAs is not intended. Furthermore, the assessments are limited...

  16. Reevaluation of the life cycle of Tuber magnatum.

    Science.gov (United States)

    Paolocci, Francesco; Rubini, Andrea; Riccioni, Claudia; Arcioni, Sergio

    2006-04-01

    Tuber spp. are ectomycorrhizal ascomycetes that produce ascocarps known as truffles. Basic aspects of Tuber biology have yet to be fully elucidated. In particular, there are conflicting hypotheses concerning the mating system and the ploidy level of the mycorrhizal and truffle hyphae. We used polymorphic microsatellites to compare the allelic configurations of asci with those from the network of the surrounding hyphae in single Tuber magnatum truffles. We then used these truffles to inoculate host plants and evaluated the microsatellite configurations of the resulting mycorrhizal root tips. These analyses provide direct evidence that T. magnatum outcrosses and that its life cycle is predominantly haploid. In addition to its scientific significance, this basic understanding of the T. magnatum life cycle may have practical importance in developing strategies to obtain and select nursery-produced mycorrhizal plants as well as in the management of artificial plantations of this and other Tuber spp.

  17. Reevaluation of the Life Cycle of Tuber magnatum†

    Science.gov (United States)

    Paolocci, Francesco; Rubini, Andrea; Riccioni, Claudia; Arcioni, Sergio

    2006-01-01

    Tuber spp. are ectomycorrhizal ascomycetes that produce ascocarps known as truffles. Basic aspects of Tuber biology have yet to be fully elucidated. In particular, there are conflicting hypotheses concerning the mating system and the ploidy level of the mycorrhizal and truffle hyphae. We used polymorphic microsatellites to compare the allelic configurations of asci with those from the network of the surrounding hyphae in single Tuber magnatum truffles. We then used these truffles to inoculate host plants and evaluated the microsatellite configurations of the resulting mycorrhizal root tips. These analyses provide direct evidence that T. magnatum outcrosses and that its life cycle is predominantly haploid. In addition to its scientific significance, this basic understanding of the T. magnatum life cycle may have practical importance in developing strategies to obtain and select nursery-produced mycorrhizal plants as well as in the management of artificial plantations of this and other Tuber spp. PMID:16597935

  18. The elusive life cycle of scyphozoan jellyfish - metagenesis revisited

    Science.gov (United States)

    Ceh, Janja; Gonzalez, Jorge; Pacheco, Aldo S.; Riascos, José M.

    2015-07-01

    Massive proliferations of scyphozoan jellyfish considerably affect human industries and irreversibly change food webs. Efforts to understand the role of jellyfish in marine ecosystems are based on a life cycle model described 200 years ago. According to this paradigm the pelagic medusae is considered seasonal and alternates with the benthic polyp stage from which it derives. However, we provide evidence that a) the occurrence of several species of medusae is not restricted to a season in the year, they overwinter, b) polyp- and medusa generations are neither temporally nor spatially separated, and c) “metagenesis” which is defined as the alternation between sexual and asexual generations does not always occur. Hence we recommend additions to the current model and argue that the scyphozoan life cycle should be considered multi-modal, rather than metagenetic. The implications of these findings for jellyfish proliferations, including possible consequences and associated environmental drivers, are discussed.

  19. The elusive life cycle of scyphozoan jellyfish – metagenesis revisited

    Science.gov (United States)

    Ceh, Janja; Gonzalez, Jorge; Pacheco, Aldo S.; Riascos, José M.

    2015-01-01

    Massive proliferations of scyphozoan jellyfish considerably affect human industries and irreversibly change food webs. Efforts to understand the role of jellyfish in marine ecosystems are based on a life cycle model described 200 years ago. According to this paradigm the pelagic medusae is considered seasonal and alternates with the benthic polyp stage from which it derives. However, we provide evidence that a) the occurrence of several species of medusae is not restricted to a season in the year, they overwinter, b) polyp- and medusa generations are neither temporally nor spatially separated, and c) “metagenesis” which is defined as the alternation between sexual and asexual generations does not always occur. Hence we recommend additions to the current model and argue that the scyphozoan life cycle should be considered multi-modal, rather than metagenetic. The implications of these findings for jellyfish proliferations, including possible consequences and associated environmental drivers, are discussed. PMID:26153534

  20. The elusive life cycle of scyphozoan jellyfish--metagenesis revisited.

    Science.gov (United States)

    Ceh, Janja; Gonzalez, Jorge; Pacheco, Aldo S; Riascos, José M

    2015-07-08

    Massive proliferations of scyphozoan jellyfish considerably affect human industries and irreversibly change food webs. Efforts to understand the role of jellyfish in marine ecosystems are based on a life cycle model described 200 years ago. According to this paradigm the pelagic medusae is considered seasonal and alternates with the benthic polyp stage from which it derives. However, we provide evidence that a) the occurrence of several species of medusae is not restricted to a season in the year, they overwinter, b) polyp- and medusa generations are neither temporally nor spatially separated, and c) "metagenesis" which is defined as the alternation between sexual and asexual generations does not always occur. Hence we recommend additions to the current model and argue that the scyphozoan life cycle should be considered multi-modal, rather than metagenetic. The implications of these findings for jellyfish proliferations, including possible consequences and associated environmental drivers, are discussed.

  1. Life cycle assessment of the Danish electricity distribution network

    DEFF Research Database (Denmark)

    Turconi, Roberto; Simonsen, Christian G.; Byriel, Inger P.

    2014-01-01

    and overhead) and 0.4 kV (copper and aluminum) were modeled. Results and discussion Electricity transmission and distribution provided nonnegligible impacts, related mainly to power losses. Impacts from electricity distribution were larger than those from transmission because of higher losses and higher......Purpose This article provides life cycle inventory data for electricity distribution networks and a life cycle assessment (LCA) of the Danish transmission and distribution networks. The aim of the study was to evaluate the potential importance of environmental impacts associated with distribution......, in current and future electricity systems. Methods The functional unit was delivery of 1 kWh of electricity in Denmark. The focus of the assessment was distribution of electricity, and the related impacts were compared to the generation and transmission of electricity, in order to evaluate the importance...

  2. Life cycle human health impacts of 875 pesticides

    DEFF Research Database (Denmark)

    Fantke, Peter; Jolliet, Oliver

    2016-01-01

    present a consistent framework for characterizing human toxicological impacts associated with pesticides applied to agricultural crops in the frame of life cycle impact assessment based on state-of-the-art data and methods. Methods We combine a dynamic multicrop plant uptake model designed for evaluating......Purpose Residues in field crops grown and harvested for human consumption are the main contributor to overall human exposure toward agricultural pesticides for the general population. However, exposure from crop residues is currently not considered in life cycle assessment practice. We therefore...... human exposure to residues for a wide range of pesticide-crop combinations with latest findings of pesticide dissipation kinetics in crops and post-harvest food processing. Outcome is a set of intake fractions and characterization factors for 875 organic pesticides and six major food crops along...

  3. Full cost accounting for the life cycle of coal.

    Science.gov (United States)

    Epstein, Paul R; Buonocore, Jonathan J; Eckerle, Kevin; Hendryx, Michael; Stout Iii, Benjamin M; Heinberg, Richard; Clapp, Richard W; May, Beverly; Reinhart, Nancy L; Ahern, Melissa M; Doshi, Samir K; Glustrom, Leslie

    2011-02-01

    Each stage in the life cycle of coal-extraction, transport, processing, and combustion-generates a waste stream and carries multiple hazards for health and the environment. These costs are external to the coal industry and are thus often considered "externalities." We estimate that the life cycle effects of coal and the waste stream generated are costing the U.S. public a third to over one-half of a trillion dollars annually. Many of these so-called externalities are, moreover, cumulative. Accounting for the damages conservatively doubles to triples the price of electricity from coal per kWh generated, making wind, solar, and other forms of nonfossil fuel power generation, along with investments in efficiency and electricity conservation methods, economically competitive. We focus on Appalachia, though coal is mined in other regions of the United States and is burned throughout the world. © 2011 New York Academy of Sciences.

  4. Towards Sustainable Construction: Life Cycle Assessment of Railway Bridges

    DEFF Research Database (Denmark)

    Du, Guangli

    Since last few decades, the increased pressure from the environmental issues of natural resource depletion, global warming and air pollution have posed a great challenge worldwide. Among all the industrial fields, bridge infrastructures and their belonged construction sector contribute to a wide....... The life cycle assessment (LCA) method has been verified as a systematic tool, which enables the fully assessment and complete comparison for the environmental impact among different bridge options through a life cycle manner. The study presented in this thesis is focused on railway bridges, as the LCA...... performance. However, the environmental profile of the structure is though very case specific; one cannot draw a general conclusion for a certain type of bridge without performing the LCA study. The case study has found that the impact of material manufacture phase is mostly identified significant among...

  5. Biology and life cycle of Amblyomma incisum (Acari: Ixodidae).

    Science.gov (United States)

    Szabó, Matias Pablo J; Pereira, Lucas de F; Castro, Márcio B; Garcia, Marcos V; Sanches, Gustavo S; Labruna, Marcelo B

    2009-07-01

    Amblyomma incisum Neumann is a major tick species in the Atlantic Forest of Brazil. Tapir is the main host for adult ticks and a high aggressiveness of nymphs to humans has been reported. In this work data on the biology and life cycle of this tick species is presented for the first time. It was shown that horse is a suitable host for A. incisum adults and rabbit for larvae and nymphs. It was also shown that A. incisum is a big tick species (mean engorged female weight of 1.96 g) with a long life cycle which lasts 262.3 days when maintained at 27 degrees C and 85% RH. These laboratory conditions were, however, inappropriate and egg hatching rate (1.2%) was very low. Nevertheless egg hatching of ticks in a forest patch increased considerably (72.2%) indicating that this A. incisum population is highly dependent on a forest-like environment.

  6. LIFE CYCLE ASSESSMENT (LCA AS A TOOL FOR BUSINESS STRATEGY

    Directory of Open Access Journals (Sweden)

    Rodrigo Salvador

    2014-09-01

    Full Text Available The growing concern about the development of sustainable production systems leads organizations to seek the support of management tools for decision-making. Considering the whole life cycle of the product, the Life Cycle Assessment (LCA has an important role in this scenario. The objective of this paper is to present, through the theoretical discussion, the role of LCA in strategic planning of the organization. It showed the enormous potential for decision making on the environmental aspect, but also the critical factor in the development shares in the competitive context. The use of LCA can reduce the environmental impacts of the system under study (primary purpose and guide the range of advantages in the fields of marketing, legislation and environmental labeling, competitive strategies, efficiency use of resources and others.

  7. Managing Life-Cycle Information of Aircraft Components

    Science.gov (United States)

    2012-04-01

    starting to implement Product Life Cycle Management ( PLM ), a closed-loop system that encompasses internationally standardized data-exchange technology...aircraft have much to gain from the use of tracking technologies in support of a PLM system. To investigate how efficiencies can be attained in the...missing the card. The problem stems from the lack of reliability of the card-based system. Moving to an automated PLM system would address these

  8. LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION

    Directory of Open Access Journals (Sweden)

    V. Sarancha

    2015-03-01

    Full Text Available Article describes the life cycle assessment method and introduces opportunities for method performance in healthcare system settings. LSA draws attention to careful use of resources, environmental, human and social responsibility. Modelling of environmental and technological inputs allows optimizing performance of the system. Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.

  9. Life cycle assessment of nanocellulose-reinforced advanced fibre composites

    OpenAIRE

    Hervy, Martin; EVANGELISTI, SARA; Lettieri, Paola; Lee, Koon-Yang

    2015-01-01

    ? 2015 The Authors. Published by Elsevier Ltd.The research and development of nanocellulose-reinforced polymer composites have dramatically increased in recent years due to the possibility of exploiting the high tensile stiffness and strength of nanocellulose. In the work, the environmental impact of bacterial cellulose (BC)- and nanofibrillated cellulose (NFC)-reinforced epoxy composites were evaluated using life cycle assessment (LCA). Neat polylactide (PLA) and 30 wt.-% randomly oriented g...

  10. Life-Cycle Educational Choices: Evidence for Two German Cohorts

    OpenAIRE

    Biewen, Martin; Tapalaga, Madalina

    2016-01-01

    We study life-cycle educational transitions in an education system characterized by early tracking and institutionalized branches of academic and vocational training but with the possibility to revise earlier decisions at later stages. Our model covers all major transitions ranging from preschool education through primary and secondary schooling to different forms of tertiary education and vocational training. We consider the role of previous decisions and background characteristics at each d...

  11. Life Cycle Assessment in Management of Socially Responsible Enterprise

    Directory of Open Access Journals (Sweden)

    Tkaczyk Stanisław

    2014-12-01

    Full Text Available The following paper presents dangerous and evident phenomenon of communicational chaos in the field of environment protection and sustainable development in a turbulent external environment. It is pointed that this phenomenon gives organizations an opportunity to take pretended pro-environmental actions, such as socially critical greenwashing. As a counterbalance to those practices, a concept of Corporate Social Responsibility (CSR is presented, underlining the possibility of developing honest environmental marketing basing on methods such as Life Cycle Assessment.

  12. Life cycle assessment of polysaccharide materials: a review

    OpenAIRE

    Shen, L; Patel, M.K.

    2008-01-01

    Apart from conventional uses of polysaccharide materials, such as food, clothing, paper packaging and construction, new polysaccharide products and materials have been developed. This paper reviews life cycle assessment (LCA) studies in order to gain insight of the environmental profiles of polysaccharide products (e.g. viscose or natural fibre polymer composites) in comparison with their conventional counterparts (e.g. cotton or petrochemical polymers). The application areas covered are text...

  13. Improving Life Cycle Management Through Simulation and Efficient Design

    Science.gov (United States)

    2008-09-01

    Designed and developed by Clockwork Solutions, the Total Life Cycle Management Assessment Tool (TLCM-AT) is a probabilistic modeling and simulation...analysis tool that uses computer models to represent a fleet of systems. TLCM-AT helps Program Managers to better understand how decisions involving...In fact, Department of Defense (DoD) leadership believes so strongly in the value that modeling and simulation (M&S) brings to LCM that DoD

  14. Aircraft bi-level life cycle cost estimation

    OpenAIRE

    Zhao, X.; Verhagen, W.J.C.; Curan, R.

    2015-01-01

    n an integrated aircraft design and analysis practice, Life Cycle Cost (LCC) is essential for decision making. The LCC of an aircraft is ordinarily partially estimated by emphasizing a specific cost type. However, an overview of the LCC including design and development cost, production cost, operating cost and disposal cost is not provided. This may produce biased cost estimates. Moreover, aircraft LCC estimation is largely dependent on the availability of input parameters. It is often a prob...

  15. Interstellar dust within the life cycle of the interstellar medium

    Directory of Open Access Journals (Sweden)

    Demyk K.

    2012-01-01

    Full Text Available Cosmic dust is omnipresent in the Universe. Its presence influences the evolution of the astronomical objects which in turn modify its physical and chemical properties. The nature of cosmic dust, its intimate coupling with its environment, constitute a rich field of research based on observations, modelling and experimental work. This review presents the observations of the different components of interstellar dust and discusses their evolution during the life cycle of the interstellar medium.

  16. Bovine eurytrematosis: life cycle, pathologic manifestations and public health considerations

    OpenAIRE

    Headley, Selwyn Arlington

    2007-01-01

    This article describes the life cycle, pathologic manifestations and aspects of public health relative to infection of Eurytrema sp. in beef cattle and offer consise information to assist those involved in meat inspection. Eurythema sp. produces intenstitial pancreatitis with subsequent ductal obstruction and is being considered as the principal cause of rejection of pancreas in some Brazilian states methods to identify and diagnose gross alterations of Eurytrema sp. in beef cattle as well as...

  17. Life cycle assessment of metals: a scientific synthesis.

    Directory of Open Access Journals (Sweden)

    Philip Nuss

    Full Text Available We have assembled extensive information on the cradle-to-gate environmental burdens of 63 metals in their major use forms, and illustrated the interconnectedness of metal production systems. Related cumulative energy use, global warming potential, human health implications and ecosystem damage are estimated by metal life cycle stage (i.e., mining, purification, and refining. For some elements, these are the first life cycle estimates of environmental impacts reported in the literature. We show that, if compared on a per kilogram basis, the platinum group metals and gold display the highest environmental burdens, while many of the major industrial metals (e.g., iron, manganese, titanium are found at the lower end of the environmental impacts scale. If compared on the basis of their global annual production in 2008, iron and aluminum display the largest impacts, and thallium and tellurium the lowest. With the exception of a few metals, environmental impacts of the majority of elements are dominated by the purification and refining stages in which metals are transformed from a concentrate into their metallic form. Out of the 63 metals investigated, 42 metals are obtained as co-products in multi output processes. We test the sensitivity of varying allocation rationales, in which the environmental burden are allocated to the various metal and mineral products, on the overall results. Monte-Carlo simulation is applied to further investigate the stability of our results. This analysis is the most comprehensive life cycle comparison of metals to date and allows for the first time a complete bottom-up estimate of life cycle impacts of the metals and mining sector globally. We estimate global direct and indirect greenhouse gas emissions in 2008 at 3.4 Gt CO2-eq per year and primary energy use at 49 EJ per year (9.5% of global use, and report the shares for all metals to both impact categories.

  18. Life-Cycle Analysis of Aircraft Turbine Engines

    Science.gov (United States)

    1977-11-01

    and batcked til Willh propter datta, thle wet i odlology presenited here, Mhould Supply .-alklablo intlorimationl With Which the inlitial 1trAdeIVl...and given an important role in selecting requirements for the final design. Commercial airlines are totally involved in the early design of the product...management must make it clear to these organizations that life-cycle analysis is here to stay. Contrac- tors must be made equally aware of their role

  19. A life cycle assessment of destruction of ammunition

    Energy Technology Data Exchange (ETDEWEB)

    Alverbro, K., E-mail: karin.alverbro@infra.kth.se [Division of Environmental Strategies Research - fms, Department of Urban Planning and Environment, School of Architecture and the Built Environment, KTH (Royal Institute of Technology), SE-100 44 Stockholm (Sweden); Bjoerklund, A., E-mail: annab@infra.kth.se [Division of Environmental Strategies Research - fms, Department of Urban Planning and Environment, School of Architecture and the Built Environment, KTH (Royal Institute of Technology), SE-100 44 Stockholm (Sweden); Finnveden, G., E-mail: goran.finnveden@infra.kth.se [Division of Environmental Strategies Research - fms, Department of Urban Planning and Environment, School of Architecture and the Built Environment, KTH (Royal Institute of Technology), SE-100 44 Stockholm (Sweden); Hochschorner, E., E-mail: eho@infra.kth.se [Division of Environmental Strategies Research - fms, Department of Urban Planning and Environment, School of Architecture and the Built Environment, KTH (Royal Institute of Technology), SE-100 44 Stockholm (Sweden); Haegvall, J., E-mail: joakim.hagvall@foi.se [FOI, Swedish Defence Research Agency, SE-164 90 Stockholm (Sweden)

    2009-10-30

    The Swedish Armed Forces have large stocks of ammunition that were produced at a time when decommissioning was not considered. This ammunition will eventually become obsolete and must be destroyed, preferably with minimal impact on the environment and in a safe way for personnel. The aim of this paper is to make a comparison of the environmental impacts in a life cycle perspective of three different methods of decommissioning/destruction of ammunition, and to identify the environmental advantages and disadvantages of each of these destruction methods: open detonation; static kiln incineration with air pollution control combined with metal recycling, and a combination of incineration with air pollution control, open burning, recovery of some energetic material and metal recycling. Data used are for the specific processes and from established LCA databases. Recycling the materials in the ammunition and minimising the spread of airborne pollutants during incineration were found to be the most important factors affecting the life cycle environmental performance of the compared destruction methods. Open detonation with or without metal recycling proved to be the overall worst alternative from a life cycle perspective. The results for the static kiln and combination treatment indicate that the kind of ammunition and location of the destruction plant might determine the choice of method, since the environmental impacts from these methods are of little difference in the case of this specific grenade. Different methods for destruction of ammunition have previously been discussed from a risk and safety perspective. This is however to our knowledge the first study looking specifically on environmentally aspect in a life cycle perspective.

  20. Life cycle cost modeling of conceptual space vehicles

    Science.gov (United States)

    Ebeling, Charles

    1993-01-01

    This paper documents progress to date by the University of Dayton on the development of a life cycle cost model for use during the conceptual design of new launch vehicles and spacecraft. This research is being conducted under NASA Research Grant NAG-1-1327. This research effort changes the focus from that of the first two years in which a reliability and maintainability model was developed to the initial development of a life cycle cost model. Cost categories are initially patterned after NASA's three axis work breakdown structure consisting of a configuration axis (vehicle), a function axis, and a cost axis. The focus will be on operations and maintenance costs and other recurring costs. Secondary tasks performed concurrent with the development of the life cycle costing model include continual support and upgrade of the R&M model. The primary result of the completed research will be a methodology and a computer implementation of the methodology to provide for timely cost analysis in support of the conceptual design activities. The major objectives of this research are: to obtain and to develop improved methods for estimating manpower, spares, software and hardware costs, facilities costs, and other cost categories as identified by NASA personnel; to construct a life cycle cost model of a space transportation system for budget exercises and performance-cost trade-off analysis during the conceptual and development stages; to continue to support modifications and enhancements to the R&M model; and to continue to assist in the development of a simulation model to provide an integrated view of the operations and support of the proposed system.

  1. Life-cycle costs of high-performance cells

    Science.gov (United States)

    Daniel, R.; Burger, D.; Reiter, L.

    1985-01-01

    A life cycle cost analysis of high efficiency cells was presented. Although high efficiency cells produce more power, they also cost more to make and are more susceptible to array hot-spot heating. Three different computer analysis programs were used: SAMICS (solar array manufacturing industry costing standards), PVARRAY (an array failure mode/degradation simulator), and LCP (lifetime cost and performance). The high efficiency cell modules were found to be more economical in this study, but parallel redundancy is recommended.

  2. Cycle life status of SAFT VOS nickel-cadmium cells

    Science.gov (United States)

    Goualard, Jacques

    1993-01-01

    The SAFT prismatic VOS Ni-Cd cells have been flown in geosynchronous orbit since 1977 and in low earth orbit since 1983. Parallel cycling tests are performed by several space agencies in order to determine the cycle life for a wide range of temperature and depth of discharge (DOD). In low Earth orbit (LEO), the ELAN program is conducted on 24 Ah cells by CNES and ESA at the European Battery Test Center at temperatures ranging from 0 to 27 C and DOD from 10 to 40 percent. Data are presented up to 37,000 cycles. One pack (X-80) has achieved 49,000 cycles at 10 C and 23 percent DOD. The geosynchronous orbit simulation of a high DOD test is conducted by ESA on 3 batteries at 10 C and 70, 90, and 100 percent DOD. Thirty-one eclipse seasons are completed, and no signs of degradation have been found. The Air Force test at CRANE on 24 Ah and 40 Ah cells at 20 C and 80 percent DOD has achieved 19 shadow periods. Life expectancy is discussed. The VOS cell technology could be used for the following: (1) in geosynchronous conditions--15 yrs at 10-15 C and 80 percent DOD; and (2) in low earth orbit--10 yrs at 5-15 C and 25-30 percent DOD.

  3. Life-cycle analysis of shale gas and natural gas.

    Energy Technology Data Exchange (ETDEWEB)

    Clark, C.E.; Han, J.; Burnham, A.; Dunn, J.B.; Wang, M. (Energy Systems); ( EVS)

    2012-01-27

    The technologies and practices that have enabled the recent boom in shale gas production have also brought attention to the environmental impacts of its use. Using the current state of knowledge of the recovery, processing, and distribution of shale gas and conventional natural gas, we have estimated up-to-date, life-cycle greenhouse gas emissions. In addition, we have developed distribution functions for key parameters in each pathway to examine uncertainty and identify data gaps - such as methane emissions from shale gas well completions and conventional natural gas liquid unloadings - that need to be addressed further. Our base case results show that shale gas life-cycle emissions are 6% lower than those of conventional natural gas. However, the range in values for shale and conventional gas overlap, so there is a statistical uncertainty regarding whether shale gas emissions are indeed lower than conventional gas emissions. This life-cycle analysis provides insight into the critical stages in the natural gas industry where emissions occur and where opportunities exist to reduce the greenhouse gas footprint of natural gas.

  4. Small business life cycle: statics and dynamics (S

    Directory of Open Access Journals (Sweden)

    Matejun Marek

    2017-12-01

    Full Text Available The aim of the paper is the presentation of theoretical foundations and the structure of original, 8-stage statics and dynamics model in the small business life cycle. Based on theoretical considerations, two hypotheses concerning the impact of dynamic and static nature of the life-cycle stages on selected determinants and effects of SMEs’ development were formulated. The hypotheses were verified based on the results of the survey conducted on a sample of 1,741 SMEs from 22 countries of the European Union. The results indicate that companies in the dynamic life-cycle stages are run by more enterprising owners, operate in more promising markets with a higher potential and make greater use of market niches thus limiting the level of competition. At the same time, such companies are characterised by higher levels of flexibility and involvement in innovative activities, which translates into obtaining a significantly higher level of business performance, in the area of quantitative as well as qualitative results.

  5. Life cycle assessment-driven selection of industrial ecology strategies.

    Science.gov (United States)

    Ardente, Fulvio; Cellura, Maurizio; Lo Brano, Valerio; Mistretta, Marina

    2010-01-01

    The paper presents an application of the Life-Cycle Assessment (LCA) to the planning and environmental management of an “eco-industrial cluster.” A feasibility study of industrial symbiosis in southern Italy is carried out, where interlinked companies share subproducts and scraps, services, structures, and plants to reduce the related environmental impact. In particular, the research focuses on new recycling solutions to create open recycling loops in which plastic subproducts and scraps are transferred to external production systems. The main environmental benefits are the reduction of resource depletion, air emissions, and landfilled wastes. The proposed strategies are also economically viable and they suggest cost abatement for the involved companies. This research shows the need for a multidisciplinary approach to data processing and to complexity managing of the investigated systems. In this context, life-cycle thinking is required to be promoted throughout the economy, as well to be as a part of all decisions on products and other criteria such as functionality, health, and safety. The Life-Cycle Assessment approach can be assumed as a methodology for influencing decision makers to make sustainable choices.

  6. Life Cycle Assessment of Waste Water Treatment Plants in Ireland

    Directory of Open Access Journals (Sweden)

    Greg Mcnamara

    2016-09-01

      The Urban Wastewater Treatment Directive 91/271/EEC introduced a series of measures for the purpose of protecting the environment from the adverse effects of effluent discharge from wastewater treatment plants.  There are environmental costs associated with attaining the required level of water quality set out in the directive such as greenhouse gas emissions due to energy production, and ecotoxicity from sludge application to land.  The goal of this study is to assess the environmental costs in an Irish context, focusing specifically on the effects of variation in scale and discharge limitation. Life cycle assessment is the analytical tool used to evaluate the environmental impact.  The life cycle impact assessment methodology developed by the Centre of Environmental Science, Leiden University (2010 has been adopted and implemented using GaBi 6.0 life cycle assessment software.  Two plants of varying size and location were chosen for the study. The study found that energy consumption and sludge application to land are the largest contributors to the overall environmental impact associated with the treatment process at both plants.  Economies of scale were observed in energy usage during secondary aeration.   

  7. Life cycle assessment of palm-derived biodiesel in Taiwan

    KAUST Repository

    Maharjan, Sumit

    2016-10-01

    In Taiwan, due to the limited capacity of waste cooking oil, palm oil has been viewed as the potential low-cost imported feedstock for producing biodiesel, in the way of obtaining oil feedstock in Malaysia and producing biodiesel in Taiwan. This study aims to evaluate the cradle-to-grave life cycle environmental performance of palm biodiesel within two different Asian countries, Malaysia and Taiwan. The phases of the life cycle such as direct land-use-change impact, plantation and milling are investigated based on the Malaysia case and those of refining, and fuel production as well as engine combustion is based on Taiwan case. The greenhouse gas (GHG) emission and energy consumption for the whole life cycle were calculated as −28.29 kg CO2-equiv. and +23.71 MJ/kg of palm-derived biodiesel. We also analyze the impacts of global warming potential (GWP) and the payback time for recovering the GHG emissions when producing and using biodiesel. Various scenarios include (1) clearing rainforest or peat-forest; (2) treating or discharging palm-oil-milling effluent (POME) are further developed to examine the effectiveness of improving the environmental impacts © 2016 Springer-Verlag Berlin Heidelberg

  8. Sampling and monitoring for the mine life cycle

    Science.gov (United States)

    McLemore, Virginia T.; Smith, Kathleen S.; Russell, Carol C.

    2014-01-01

    Sampling and Monitoring for the Mine Life Cycle provides an overview of sampling for environmental purposes and monitoring of environmentally relevant variables at mining sites. It focuses on environmental sampling and monitoring of surface water, and also considers groundwater, process water streams, rock, soil, and other media including air and biological organisms. The handbook includes an appendix of technical summaries written by subject-matter experts that describe field measurements, collection methods, and analytical techniques and procedures relevant to environmental sampling and monitoring.The sixth of a series of handbooks on technologies for management of metal mine and metallurgical process drainage, this handbook supplements and enhances current literature and provides an awareness of the critical components and complexities involved in environmental sampling and monitoring at the mine site. It differs from most information sources by providing an approach to address all types of mining influenced water and other sampling media throughout the mine life cycle.Sampling and Monitoring for the Mine Life Cycle is organized into a main text and six appendices that are an integral part of the handbook. Sidebars and illustrations are included to provide additional detail about important concepts, to present examples and brief case studies, and to suggest resources for further information. Extensive references are included.

  9. Resolving the life cycle alters expected impacts of climate change.

    Science.gov (United States)

    Levy, Ofir; Buckley, Lauren B; Keitt, Timothy H; Smith, Colton D; Boateng, Kwasi O; Kumar, Davina S; Angilletta, Michael J

    2015-08-22

    Recent models predict contrasting impacts of climate change on tropical and temperate species, but these models ignore how environmental stress and organismal tolerance change during the life cycle. For example, geographical ranges and extinction risks have been inferred from thermal constraints on activity during the adult stage. Yet, most animals pass through a sessile embryonic stage before reaching adulthood, making them more susceptible to warming climates than current models would suggest. By projecting microclimates at high spatio-temporal resolution and measuring thermal tolerances of embryos, we developed a life cycle model of population dynamics for North American lizards. Our analyses show that previous models dramatically underestimate the demographic impacts of climate change. A predicted loss of fitness in 2% of the USA by 2100 became 35% when considering embryonic performance in response to hourly fluctuations in soil temperature. Most lethal events would have been overlooked if we had ignored thermal stress during embryonic development or had averaged temperatures over time. Therefore, accurate forecasts require detailed knowledge of environmental conditions and thermal tolerances throughout the life cycle. © 2015 The Author(s).

  10. Life-Cycle Evaluation of Domestic Energy Systems

    Science.gov (United States)

    Bando, Shigeru; Hihara, Eiji

    Among the growing number of environmental issues, the global warming due to the increasing emission of greenhouse gases, such as carbon dioxide CO2, is the most serious one. In order to reduce CO2 emissions in energy use, it is necessary to reduce primary energy consumption, and to replace energy sources with alternatives that emit less CO2.One option of such ideas is to replace fossil gas for water heating with electricity generated by nuclear power, hydraulic power, and other methods with low CO2 emission. It is also important to use energy efficiently and to reduce waste heat. Co-generation system is one of the applications to be able to use waste heat from a generator as much as possible. The CO2 heat pump water heaters, the polymer electrolyte fuel cells, and the micro gas turbines have high potential for domestic energy systems. In the present study, the life-cycle cost, the life-cycle consumption of primary energy and the life-cycle emission of CO2 of these domestic energy systems are compare. The result shows that the CO2 heat pump water heaters have an ability to reduce CO2 emission by 10%, and the co-generation systems also have another ability to reduce primary energy consumption by 20%.

  11. New insights into the life cycle of Platynosomum (Trematoda: Dicrocoeliidae).

    Science.gov (United States)

    Pinto, Hudson A; Mati, Vitor L T; de Melo, Alan L

    2014-07-01

    The platynosomiasis, a worldwide parasitic disease with importance for domestic cat, has an etiological agent species of trematodes of the genus Platynosomum, whose complete life cycles are not yet known. The real role of lizards in the transmission of this dicrocoeliid parasite (as obligatory intermediate or paratenic host) still needs to be defined. In the present study, oval-shaped encysted metacercariae obtained from terrestrial isopods (Oniscidea sp. and Nagurus nanus) and elongated excysted metacercariae found in biliary ducts and gallbladder of lizards (Hemidactylus mabouia) in Brazil were used for morphological characterization and experimental infection of mice. Adult parasites recovered from bile ducts and liver of mice inoculated orally with metacercariae from both hosts (isopods and lizards) were identified as Platynosomum illiciens (=Platynosomum fastosum), showing that lizards are paratenic (not obligatory) hosts involved in the life cycle of this parasite. Moreover, Subulina octona is reported as the first intermediate host of P. illiciens in South America, and terrestrial isopods are presented here as new natural second intermediate hosts of the parasite. Finally, it is pointed out that high prevalence and intensity of infection of intermediate and paratenic hosts were observed. These findings on the life cycle of P. illiciens are relevant considering that they may indicate possible control measures of platynosomiasis.

  12. A CONCEPTUAL MODEL OF THE LIFE CYCLE OF THE PROGRAM

    Directory of Open Access Journals (Sweden)

    Марія Костянтинівна СУХОНОС

    2016-02-01

    Full Text Available A conceptual model of the life cycle of the program is proposed. This model is based on the value approach. As a resulting index, it uses a category of complex structural value. This model renders the process of the life cycle of the program in the context of time/result. It assumes the presence of four basic phases of the life cycle, namely, initiation, planning, executing and closing. Also, this model formalizes interconnection of management processes of integration of program and management of its community and subprocesses. Selection of a value approach for the forming of a resulting index of a program determines by a variety of results of the program. This is a result of its variety and complexity in the process of finding a criterion for evaluation. Worked out a mechanism for assessing the value of the program. It consists of four steps and involves using of conventional methods (decomposition and expert estimates. As a unit of measurement assumes to use points and rating scale with the maximum score a hundred points. A complex value, which is evaluated at one hundred points, is a result of the program. It is critically important in the process of current and final evaluation of the program.

  13. Fragmentation modes and the evolution of life cycles.

    Science.gov (United States)

    Pichugin, Yuriy; Peña, Jorge; Rainey, Paul B; Traulsen, Arne

    2017-11-01

    Reproduction is a defining feature of living systems. To reproduce, aggregates of biological units (e.g., multicellular organisms or colonial bacteria) must fragment into smaller parts. Fragmentation modes in nature range from binary fission in bacteria to collective-level fragmentation and the production of unicellular propagules in multicellular organisms. Despite this apparent ubiquity, the adaptive significance of fragmentation modes has received little attention. Here, we develop a model in which groups arise from the division of single cells that do not separate but stay together until the moment of group fragmentation. We allow for all possible fragmentation patterns and calculate the population growth rate of each associated life cycle. Fragmentation modes that maximise growth rate comprise a restrictive set of patterns that include production of unicellular propagules and division into two similar size groups. Life cycles marked by single-cell bottlenecks maximise population growth rate under a wide range of conditions. This surprising result offers a new evolutionary explanation for the widespread occurrence of this mode of reproduction. All in all, our model provides a framework for exploring the adaptive significance of fragmentation modes and their associated life cycles.

  14. Postwar fertility cycles and the Easterlin hypothesis: a life-cycle approach.

    Science.gov (United States)

    Moffitt, R A

    1982-01-01

    The Easterlin hypothesis is discussed in the context of the life-cycle model. Fertility rates rose by 15% after World War II, and have fallen steadily since. The Easterlin hypothesis states that such a pattern could be generated if each generation makes its fertility decisions based on its own income relative to the income of its parental generation. The income of one generation determines the level of material well-being to which its children become accustomed; when the children grow up they will desire material goods rather than children in order to retain the lifestyle they are accustomed to. In the traditional statement of the hypothesis, relative income is defined as some ratio of the current incomes of 2 generations at particular points in time; from the viewpoint of the life-cycle theory, the concept of the income of a cohort is replaced by the concept of lifetime wealth, the value of the income received over the entire life cycle. In this article, a value of lifetime wealth is constructed for each of the cohorts of childbearing age in the postwar period and for each of their parental cohorts. Regression analysis is employed to determine whether the lifetime wealth of a cohorts' parents significantly affects its fertility. Parental wealth has a strong negative effect on a cohort's age-specific fertility rate and own-cohort wealth is found to have a positive effect on fertility rates. This article contains a discussion of the life-cycle model, explains the regression equation, presents the method used to estimate lifetime wealth and fertility regressions, and provides an examination of the effect of own and parental wealth on a cohort's pattern of female labor force participation. There appear to be underlying trends in fertility rates that are independent of relative wealth, but this article demonstrates that the Easterlin hypothesis provides at least a strong partial explanation for postwar fertility cycles.

  15. Roles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host Cells

    Directory of Open Access Journals (Sweden)

    Di Sun

    2016-03-01

    Full Text Available The Picornaviridae family comprises a large group of non-enveloped viruses that have a major impact on human and veterinary health. The viral genome contains one open reading frame encoding a single polyprotein that can be processed by viral proteinases. The crucial 3C proteinases (3Cpros of picornaviruses share similar spatial structures and it is becoming apparent that 3Cpro plays a significant role in the viral life cycle and virus host interaction. Importantly, the proteinase and RNA-binding activity of 3Cpro are involved in viral polyprotein processing and the initiation of viral RNA synthesis. In addition, 3Cpro can induce the cleavage of certain cellular factors required for transcription, translation and nucleocytoplasmic trafficking to modulate cell physiology for viral replication. Due to interactions between 3Cpro and these essential factors, 3Cpro is also involved in viral pathogenesis to support efficient infection. Furthermore, based on the structural conservation, the development of irreversible inhibitors and discovery of non-covalent inhibitors for 3Cpro are ongoing and a better understanding of the roles played by 3Cpro may provide insights into the development of potential antiviral treatments. In this review, the current knowledge regarding the structural features, multiple functions in the viral life cycle, pathogen host interaction, and development of antiviral compounds for 3Cpro is summarized.

  16. The elemental composition of virus particles: implications for marine biogeochemical cycles.

    Science.gov (United States)

    Jover, Luis F; Effler, T Chad; Buchan, Alison; Wilhelm, Steven W; Weitz, Joshua S

    2014-07-01

    In marine environments, virus-mediated lysis of host cells leads to the release of cellular carbon and nutrients and is hypothesized to be a major driver of carbon recycling on a global scale. However, efforts to characterize the effects of viruses on nutrient cycles have overlooked the geochemical potential of the virus particles themselves, particularly with respect to their phosphorus content. In this Analysis article, we use a biophysical scaling model of intact virus particles that has been validated using sequence and structural information to quantify differences in the elemental stoichiometry of marine viruses compared with their microbial hosts. By extrapolating particle-scale estimates to the ecosystem scale, we propose that, under certain circumstances, marine virus populations could make an important contribution to the reservoir and cycling of oceanic phosphorus.

  17. How can a life cycle inventory parametric model streamline life cycle assessment in the wooden pallet sector?

    DEFF Research Database (Denmark)

    Niero, Monia; Felice, Francesco, Di; Ren, Jingzheng

    2014-01-01

    -based regression and one multiple non-linear regression allowed to define a correlation between the life cycle impact assessment (LCIA) category indicators considered and the most influencing parameters. Conclusions The definition of LCI parametric model in the wooden pallet sector can effectively be used......Purpose This study discusses the use of parameterization within the life cycle inventory (LCI) in the wooden pallet sector, in order to test the effectiveness of LCI parametric models to calculate the environmental impacts of similar products. Starting from a single case study, the objectives...... of this paper are (1) to develop a LCI parametric model adaptable to a range of wooden pallets, (2) to test this model with a reference product (non-reversible pallet with four-way blocks) and (3) to determine numerical correlations between the environmental impacts and the most significant LCI parameters...

  18. Inhibitory Effects of Resveratrol on the Epstein-Barr Virus Lytic Cycle

    Directory of Open Access Journals (Sweden)

    Tsuey-Pin Lin

    2010-10-01

    Full Text Available Reactivation of Epstein-Barr virus (EBV from latency to the lytic cycle is required for the production of viral particles. Here, we examine the capacity of resveratrol to inhibit the EBV lytic cycle. Our results show that resveratrol inhibits the transcription of EBV immediate early genes, the expression of EBV lytic proteins, including Rta, Zta, and EA-D and reduces viron production, suggesting that this compound may be useful for preventing the proliferation of the virus.

  19. Performance improvement: an active life cycle product management

    Science.gov (United States)

    Cucchiella, Federica; Gastaldi, Massimo; Lenny Koh, S. C.

    2010-03-01

    The management of the supply chain has gained importance in many manufacturing firms. Operational flexibility can be considered a crucial weapon to increase competitiveness in a turbulent marketplace. It reflects the ability of a firm to properly and rapidly respond to a variable and dynamic environment. For the firm operating in a fashion sector, the management of the supply chain is even more complex because the product life cycle is shorter than that of the firm operating in a non-fashion sector. The increase of firm flexibility level can be reached through the application of the real option theory inside the firm network. In fact, real option may increase the project value by allowing managers to more efficiently direct the production. The real option application usually analysed in literature does not take into account that the demands of products are well-defined by the product life cycle. Working on a fashion sector, the life cycle pattern is even more relevant because of an expected demand that grows according to a constant rate that does not capture the demand dynamics of the underlying fashion goods. Thus, the primary research objective of this article is to develop a model useful for the management of investments in a supply chain operating in a fashion sector where the system complexity is increased by the low level of unpredictability and stability that is proper of the mood phenomenon. Moreover, unlike the traditional model, a real option framework is presented here that considers fashion product characterised by uncertain stages of the production cycle.

  20. Electrons, life and the evolution of Earth's oxygen cycle.

    Science.gov (United States)

    Falkowski, Paul G; Godfrey, Linda V

    2008-08-27

    The biogeochemical cycles of H, C, N, O and S are coupled via biologically catalysed electron transfer (redox) reactions. The metabolic processes responsible for maintaining these cycles evolved over the first ca 2.3 Ga of Earth's history in prokaryotes and, through a sequence of events, led to the production of oxygen via the photobiologically catalysed oxidation of water. However, geochemical evidence suggests that there was a delay of several hundred million years before oxygen accumulated in Earth's atmosphere related to changes in the burial efficiency of organic matter and fundamental alterations in the nitrogen cycle. In the latter case, the presence of free molecular oxygen allowed ammonium to be oxidized to nitrate and subsequently denitrified. The interaction between the oxygen and nitrogen cycles in particular led to a negative feedback, in which increased production of oxygen led to decreased fixed inorganic nitrogen in the oceans. This feedback, which is supported by isotopic analyses of fixed nitrogen in sedimentary rocks from the Late Archaean, continues to the present. However, once sufficient oxygen accumulated in Earth's atmosphere to allow nitrification to out-compete denitrification, a new stable electron 'market' emerged in which oxygenic photosynthesis and aerobic respiration ultimately spread via endosymbiotic events and massive lateral gene transfer to eukaryotic host cells, allowing the evolution of complex (i.e. animal) life forms. The resulting network of electron transfers led a gas composition of Earth's atmosphere that is far from thermodynamic equilibrium (i.e. it is an emergent property), yet is relatively stable on geological time scales. The early coevolution of the C, N and O cycles, and the resulting non-equilibrium gaseous by-products can be used as a guide to search for the presence of life on terrestrial planets outside of our Solar System.

  1. Life cycle assessment study of a Chinese desktop personal computer.

    Science.gov (United States)

    Duan, Huabo; Eugster, Martin; Hischier, Roland; Streicher-Porte, Martin; Li, Jinhui

    2009-02-15

    Associated with the tremendous prosperity in world electronic information and telecommunication industry, there continues to be an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of electronic and electric products (e-products). China's importance as both a consumer and supplier of e-products has grown at an unprecedented pace in recent decade. Hence, this paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese e-products from a global level. A desktop personal computer system has been selected to carry out a detailed and modular LCA which follows the ISO 14040 series. The LCA is constructed by SimaPro software version 7.0 and expressed with the Eco-indicator'99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the so-called CML method is used in order to estimate the influence of the choice of the assessment method on the result. Life cycle inventory information is complied by ecoinvent 1.3 databases, combined with literature and field investigations on the present Chinese situation. The established LCA study shows that that the manufacturing and the use of such devices are of the highest environmental importance. In the manufacturing of such devices, the integrated circuits (ICs) and the Liquid Crystal Display (LCD) are those parts contributing most to the impact. As no other aspects are taken into account during the use phase, the impact is due to the way how the electricity is produced. The final process steps--i.e. the end of life phase--lead to a clear environmental benefit if a formal and modern, up-to-date technical system is assumed, like here in this study.

  2. Universal quinone electrodes for long cycle life aqueous rechargeable batteries

    Science.gov (United States)

    Liang, Yanliang; Jing, Yan; Gheytani, Saman; Lee, Kuan-Yi; Liu, Ping; Facchetti, Antonio; Yao, Yan

    2017-08-01

    Aqueous rechargeable batteries provide the safety, robustness, affordability, and environmental friendliness necessary for grid storage and electric vehicle operations, but their adoption is plagued by poor cycle life due to the structural and chemical instability of the anode materials. Here we report quinones as stable anode materials by exploiting their structurally stable ion-coordination charge storage mechanism and chemical inertness towards aqueous electrolytes. Upon rational selection/design of quinone structures, we demonstrate three systems that coupled with industrially established cathodes and electrolytes exhibit long cycle life (up to 3,000 cycles/3,500 h), fast kinetics (>=20C), high anode specific capacity (up to 200-395 mAh g-1), and several examples of state-of-the-art specific energy/energy density (up to 76-92 Wh kg-1/ 161-208 Wh l-1) for several operational pH values (-1 to 15), charge carrier species (H+, Li+, Na+, K+, Mg2+), temperature (-35 to 25 °C), and atmosphere (with/without O2), making them a universal anode approach for any aqueous battery technology.

  3. Life cycle models of conventional and alternative-fueled automobiles

    Science.gov (United States)

    Maclean, Heather Louise

    This thesis reports life cycle inventories of internal combustion engine automobiles with feasible near term fuel/engine combinations. These combinations include unleaded gasoline, California Phase 2 Reformulated Gasoline, alcohol and gasoline blends (85 percent methanol or ethanol combined with 15 percent gasoline), and compressed natural gas in spark ignition direct and indirect injection engines. Additionally, I consider neat methanol and neat ethanol in spark ignition direct injection engines and diesel fuel in compression ignition direct and indirect injection engines. I investigate the potential of the above options to have a lower environmental impact than conventional gasoline-fueled automobiles, while still retaining comparable pricing and consumer benefits. More broadly, the objective is to assess whether the use of any of the alternative systems will help to lead to the goal of a more sustainable personal transportation system. The principal tool is the Economic Input-Output Life Cycle Analysis model which includes inventories of economic data, environmental discharges, and resource use. I develop a life cycle assessment framework to assemble the array of data generated by the model into three aggregate assessment parameters; economics, externalities, and vehicle attributes. The first step is to develop a set of 'comparable cars' with the alternative fuel/engine combinations, based on characteristics of a conventional 1998 gasoline-fueled Ford Taurus sedan, the baseline vehicle for the analyses. I calculate the assessment parameters assuming that these comparable cars can attain the potential thermal efficiencies estimated by experts for each fuel/engine combination. To a first approximation, there are no significant differences in the assessment parameters for the vehicle manufacture, service, fixed costs, and the end-of-life for any of the options. However, there are differences in the vehicle operation life cycle components and the state of technology

  4. Global guidance on environmental life cycle impact assessment indicators: Progress and case study

    DEFF Research Database (Denmark)

    Frischknecht, Rolf; Fantke, Peter; Tschümperlin, Laura

    2016-01-01

    Purpose The life cycle impact assessment (LCIA) guidance flagship project of the United Nations Environment Programme (UNEP)/Society of Environmental Toxicology and Chemistry (SETAC) Life Cycle Initiative aims at providing global guidance and building scientific consensus on environmental LCIA...

  5. Lithium/disulfide cells capable of long cycle life

    Science.gov (United States)

    Kaun, T. D.; Holifield, T. F.; Deluca, W. H.

    The lithium-alloy/disulfide cell has undergone improvements to provide a very stable, high performance Upper-Plateau (UP) FeS2 electrode. Prismatic UP FeS2 cell tests (12 to 24 Ah capacity) with a LiCl-LiBr-KBr eutectic electrolyte have demonstrated 1000 deep discharge cycles at 400 C with less than a 20 percent drop in capacity and without reduced power capability. Previous lithium-alloy/disulfide cells, which were based on a two voltage-plateau FeS2 electrode and LiCl-KCl eutectic electrolyte had a life expectancy of only 100 cycles. Both time- and cycle-related capacity loss mechanisms have been eliminated with the improved cell design. In addition, new cell design features of overcharge tolerance and overdischarge safeguarding enhance battery durability. The performance prospects of a Li-alloy/UP FeS2 battery for an IDSEP van application are discussed. A specific energy of 150 Wh/kg for this battery after 1000 cycles of operation is projected.

  6. Lithium/disulfide cells capable of long cycle life

    Energy Technology Data Exchange (ETDEWEB)

    Kaun, T.D.; Holifield, T.F.; DeLuca, W.H.

    1988-01-01

    The lithium-alloy/disulfide cell has undergone improvements to provide a very stable, high performance upper-plateau (UP) FeS/sub 2/ electrode. Prismatic UP FeS/sub 2/ cell tests (12--24 Ah capacity) with a LiCl-LiBr-KBr eutectic electrolyte have demonstrated 1000 deep discharge cycles at 400/degree/C with less than a 20% drop in capacity and without reduced power capability. Previous lithium-alloy/disulfide cells, which were based on a two voltage-plateau FeS/sub 2/ electrode and LiCl-KCl eutectic electrolyte had a life expectancy of only 100 cycles. Both time- and cycle-related capacity loss mechanisms have been eliminated with the improved cell design. In addition, new cell design features of overcharge tolerance and overdischarge safeguarding enhance battery durability. The performance prospects of a Li-alloy/UP FeS/sub 2/ battery for an IDSEP van application are discussed. A specific energy of 150 Wh/kg for this battery after 1000 cycles of operation is projected. 8 refs., 5 figs., 1 tab.

  7. Life Cycle Tests on a Hollow Cathode Based Plasma Contactor

    Science.gov (United States)

    Vaughn, Jason A.; Schneider, Todd A.; Munafo, Paul (Technical Monitor)

    2001-01-01

    The propulsive Small Expendable Deployer System (ProSEDS) mission is designed to provide an on-orbit demonstration of the electrodynamic propulsion capabilities of tethers in space. The ProSEDS experiment will be a secondary payload on a Delta II unmanned expendable booster with a mission duration of 12 days. A 5-km conductive tether is attached to the Delta II second stage and collects current from the low Earth orbit (LEO) plasma, and a Hollow Cathode Plasma Contactor (HCPC) emits the collected electrons from the Delta II, completing the electrical circuit to the ambient plasma. The HCPC for the ProSEDS mission have made it necessary to turn off the HCPC once a minute throughout the entire mission. Because of the unusual operating requirements by the ProSEDS mission, an engineering development unit of the HCPC was built to demonstrate the HCPC design would start reliably for the life of the ProSEDS mission. During the life test the engineering unit cycled for over 10,000 on/off cycles without missing a single start, and during that same test the HCPC unit demonstrated the capability to emit 0 to 5 A electron emission current. The performance of the HCPC unit during this life test will be discussed.

  8. Chromatinization of the KSHV Genome During the KSHV Life Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Uppal, Timsy [Department of Microbiology and Immunology, School of Medicine, University of Nevada, 1664 N Virginia Street, MS 320, Reno, NV 89557 (United States); Jha, Hem C. [Department of Microbiology and the Tumor Virology Program of the Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 201E Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 (United States); Verma, Subhash C. [Department of Microbiology and Immunology, School of Medicine, University of Nevada, 1664 N Virginia Street, MS 320, Reno, NV 89557 (United States); Robertson, Erle S., E-mail: erle@mail.med.upenn.edu [Department of Microbiology and the Tumor Virology Program of the Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 201E Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 (United States)

    2015-01-14

    Kaposi’s sarcoma-associated herpesvirus (KSHV) belongs to the gamma herpesvirus family and is the causative agent of various lymphoproliferative diseases in humans. KSHV, like other herpesviruses, establishes life-long latent infection with the expression of a limited number of viral genes. Expression of these genes is tightly regulated by both the viral and cellular factors. Recent advancements in identifying the expression profiles of viral transcripts, using tilling arrays and next generation sequencing have identified additional coding and non-coding transcripts in the KSHV genome. Determining the functions of these transcripts will provide a better understanding of the mechanisms utilized by KSHV in altering cellular pathways involved in promoting cell growth and tumorigenesis. Replication of the viral genome is critical in maintaining the existing copies of the viral episomes during both latent and lytic phases of the viral life cycle. The replication of the viral episome is facilitated by viral components responsible for recruiting chromatin modifying enzymes and replication factors for altering the chromatin complexity and replication initiation functions, respectively. Importantly, chromatin modification of the viral genome plays a crucial role in determining whether the viral genome will persist as latent episome or undergo lytic reactivation. Additionally, chromatinization of the incoming virion DNA, which lacks chromatin structure, in the target cells during primary infection, helps in establishing latent infection. Here, we discuss the recent advancements on our understating of KSHV genome chromatinization and the consequences of chromatin modifications on viral life cycle.

  9. Chromatinization of the KSHV Genome During the KSHV Life Cycle

    Directory of Open Access Journals (Sweden)

    Timsy Uppal

    2015-01-01

    Full Text Available Kaposi’s sarcoma-associated herpesvirus (KSHV belongs to the gamma herpesvirus family and is the causative agent of various lymphoproliferative diseases in humans. KSHV, like other herpesviruses, establishes life-long latent infection with the expression of a limited number of viral genes. Expression of these genes is tightly regulated by both the viral and cellular factors. Recent advancements in identifying the expression profiles of viral transcripts, using tilling arrays and next generation sequencing have identified additional coding and non-coding transcripts in the KSHV genome. Determining the functions of these transcripts will provide a better understanding of the mechanisms utilized by KSHV in altering cellular pathways involved in promoting cell growth and tumorigenesis. Replication of the viral genome is critical in maintaining the existing copies of the viral episomes during both latent and lytic phases of the viral life cycle. The replication of the viral episome is facilitated by viral components responsible for recruiting chromatin modifying enzymes and replication factors for altering the chromatin complexity and replication initiation functions, respectively. Importantly, chromatin modification of the viral genome plays a crucial role in determining whether the viral genome will persist as latent episome or undergo lytic reactivation. Additionally, chromatinization of the incoming virion DNA, which lacks chromatin structure, in the target cells during primary infection, helps in establishing latent infection. Here, we discuss the recent advancements on our understating of KSHV genome chromatinization and the consequences of chromatin modifications on viral life cycle.

  10. Sensor-embedded computers for better life-cycle management

    Science.gov (United States)

    Vadde, Srikanth; Kamarthi, Sagar V.; Gupta, Surendra M.; Zeid, Ibrahim

    2004-12-01

    This research investigates the advantages offered by embedded sensors for cost-effective and environmentally benign product life cycle management for desktop computers. During their use by customers as well as at the end of their lives, Sensor Embedded Computers (SECs) by virtue of sensors embedded in them generate data and information pertaining to the conditions and remaining lives of important components such as hard-drive, motherboard, and power supply unit. A computer monitoring framework is proposed to provide more customer comfort, reduce repair costs and increase the effectiveness of current disassembly practices. The framework consists of SECs, remote monitoring center (RMC), repair/service, disassembly, and disposal centers. The RMC collects dynamic data/information generated by sensors during computer usage as well as static data/information from the original equipment manufacturers (OEMs). The RMC forwards this data/information to the repair/service, disassembly, and disposal centers on need-basis. The knowledge about the condition and remaining life of computer components can be advantageously used for planning repair/service and disassembly operations as well as for building refurbished computers with known expected lives. Simulation model of the framework is built and is evaluated in terms of the following performance measures: average downtime of a computer, average repair/service cost of a computer, average disassembly cost of a computer, and average life cycle cost of a computer. Test results show that embedding sensors in computers provides a definite advantage over conventional computers in terms of the performance measures.

  11. A role for symplastic gating in the control of the potato tuber life cycle

    OpenAIRE

    Hancock, Robert D; Roberts, Alison G; Viola, Roberto

    2008-01-01

    The control of the potato tuber life cycle has been the subject of significant interest over many years. A number of different approaches have been adopted and data is available regarding hormonal, metabolic and gene expression changes that occur over the tuber life cycle. Despite this intense effort, no unifying model for the control of the potato tuber life cycle has emerged. We have undertaken a detailed analysis of the tuber life cycle utilising physiological, biochemical and cell-biologi...

  12. Integrated manure utilization system life-cycle value assessment

    Energy Technology Data Exchange (ETDEWEB)

    Row, J.; Neabel, D. [Pembina Inst. for Appropriate Development, Drayton Valley, AB (Canada)

    2005-10-15

    A life-cycle assessment of the Alberta Research Council (ARC) and Highmark Renewables' development of an integrated manure utilization system (IMUS) were presented. The assessment focused on an evaluation of factors of primary importance to government, investors and the livestock industry. IMUS technology uses manure as a resource to produce electricity, heat, bio-based fertilizer and reusable water. Results of the assessment indicated that IMUS plants have the potential to be financially viable if a power purchase of $90 MWh on average can be purchased from a 30,000 head livestock operation. A capital cost of under $11 million is necessary, and an established biofertilizer price of $50 per tonne should be established. An IMUS plant was estimated to reduce life-cycle greenhouse gas emissions by 70 to 80 per cent when compared to land spreading. Reductions are accomplished through displacing electricity from the provincial grid and reducing nitrous oxide (N{sub 2}O) emissions from spreading of manure The IMUS plants lessen environment impacts by reducing the extraction and consumption of non-renewable resources, and by displacing an estimated 11,700 GJ of coal and natural gas per 1000 head of cattle per year. In addition, various pathogens within manure are eliminated. The plants have the potential to eliminate the environmental hazards associated with the disposal of deadstock. The systems reduce manure odour, lessen truck traffic and are expected to contribute to rural economic diversification. Barriers to further implementation of IMUS were discussed, as well as emerging opportunities for IMUS developers. It was concluded that the initial assessments of the IMUS were positive. Further investigation is needed to determine actual life-cycle performance of the operations. 18 refs., 3 tabs., 3 figs.

  13. Life cycle variation of Myzus persicae (Hemiptera: Aphididae) in Greece.

    Science.gov (United States)

    Margaritopoulos, J T; Tsitsipis, J A; Goudoudaki, S; Blackman, R L

    2002-08-01

    During the years 1995-1999 the life cycle category of 2797 clones of Myzus persicae (Sulzer) was examined. The clones originated from primary and secondary hosts from different localities of North and Central Greece and the island of Crete in the south. Four different overwintering life cycle strategies were found that have also been described for M. persicae and other heteroecious species previously. A geographical variation was found in the proportion of holocyclic clones from tobacco and other secondary hosts associated with the abundance of the primary host in the sampling regions. In Central Macedonia, around the main peach-growing regions, the proportion of holocyclic clones was mostly above 50% and in some cases reached 100%. In localities of East Macedonia, holocyclic clones were also frequent. On the other hand, further south or in north-eastern Greece, where peach is not common, the proportion of holocyclic clones varied between 0 and 33%. Fifty seven percent of examined anholocyclic clones produced males under short day conditions, suggesting that androcyclic clones in Greece represent an important factor of genetic variability. Intermediate clones were sampled from all host-plants but at low frequencies (3.6% of total examined clones and 6.9% of non-holocyclic ones). Moreover, a regional variation was found in different colour forms feeding on tobacco plants. Red clones were predominant in regions where aphids overwinter parthenogenetically on weeds or winter crops. However, almost all clones from the primary host were green. The ecological aspects of life cycle variation are discussed.

  14. Life Cycle Assessment and Risk Assessment: A Methodological Comparison

    DEFF Research Database (Denmark)

    Olsen, Stig Irving; Christensen, Frans Møller; Hauschild, Michael Zwicky

    2001-01-01

    Life Cycle Assessment and Risk Assessment are two different tools in environmental management. The paper identifies harmonies, discrepancies and relations between the two tools exemplified by the risk assessment principles of the European Commission (EC) and the LCA method ‘EDIP’ (En......-vironmental Design of Industrial Products) developed in Denmark, respectively. A very important feature of LCA is the relative assessment due to the use of a functional unit. Risk assessment on the other hand is an absolute assessment, which may require very specific and detailed information on e.g. the exposure...

  15. Inclusion of Social Aspects in Life Cycle Assessment of Products

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla

    about their direct and indirect social impacts throughout the life cycle of their products. The developed methodology of Social LCA consists of (1) a framework for Social LCA (2) a method to perform quantitative Social LCA (phases, steps and activities), and (3) methods and principles to develop...... underlying modelling of social impacts. Concrete models for inclusion of four impact categories representing fundamental labour rights violations are developed and tested in six case studies. The results of the case studies are used to evaluate the Social LCA method and the specific models for labour rights...

  16. Optimal Housing, Consumption, and Investment Decisions over the Life Cycle

    DEFF Research Database (Denmark)

    Kraft, Holger; Munk, Claus

    2011-01-01

    We derive explicit solutions to life-cycle utility maximization problems involving stock and bond investment, perishable consumption, and the rental and ownership of residential real estate. Prices of houses, stocks and bonds, and labor income are correlated. Because of a positive correlation...... additional housing units (for renting out) or house price–linked financial assets. In the final years, preferences shift back to home rental. The derived strategies are still useful if housing positions are only reset infrequently. Our results suggest that markets for real estate investment trusts or other...

  17. Life cycle assessment of electricity generation in Mexico

    OpenAIRE

    Santoyo-Castelazo, E.; Gujba, H.; Azapagic, A.

    2011-01-01

    This paper presents for the first time a Life Cycle Assessment (LCA) study of electricity generation in Mexico. The electricity mix in Mexico is dominated by fossil fuels, which contribute around 79% to the total primary energy; renewable energies contribute 16.5% (hydropower 13.5%, geothermal 3% and wind 0.02%) and the remaining 4.8% is from nuclear power. The LCA results show that 225 TWh of electricity generate about 129 million tonnes of CO2 eq. per year, of which the majority (87%) is du...

  18. Infrastructures and Life-Cycle Cost-Benefit Analysis

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    2012-01-01

    Design and maintenance of infrastructures using Life-Cycle Cost-Benefit analysis is discussed in this paper with special emphasis on users costs. This is for several infrastructures such as bridges, highways etc. of great importance. Repair or/and failure of infrastructures will usually result...... in user costs greater than the repair or replacement costs of the infrastructure. For the society (and the users) it is therefore of great importance that maintenance or replacement of an infrastructure is performed in such a way that all costs are minimized - not only the owners cost....

  19. A Life-Cycle Comparison of Alternative Automobile Fuels.

    Science.gov (United States)

    MacLean, Heather L; Lave, Lester B; Lankey, Rebecca; Joshi, Satish

    2000-10-01

    We examine the life cycles of gasoline, diesel, compressed natural gas (CNG), and ethanol (C2H5OH)-fueled internal combustion engine (ICE) automobiles. Port and direct injection and spark and compression ignition engines are examined. We investigate diesel fuel from both petroleum and biosources as well as C2H5OH from corn, herbaceous bio-mass, and woody biomass. The baseline vehicle is a gasoline-fueled 1998 Ford Taurus. We optimize the other fuel/powertrain combinations for each specific fuel as a part of making the vehicles comparable to the baseline in terms of range, emissions level, and vehicle lifetime. Life-cycle calculations are done using the economic input-output life-cycle analysis (EIO-LCA) software; fuel cycles and vehicle end-of-life stages are based on published model results. We find that recent advances in gasoline vehicles, the low petroleum price, and the extensive gasoline infrastructure make it difficult for any alternative fuel to become commercially viable. The most attractive alternative fuel is compressed natural gas because it is less expensive than gasoline, has lower regulated pollutant and toxics emissions, produces less greenhouse gas (GHG) emissions, and is available in North America in large quantities. However, the bulk and weight of gas storage cylinders required for the vehicle to attain a range comparable to that of gasoline vehicles necessitates a redesign of the engine and chassis. Additional natural gas transportation and distribution infrastructure is required for large-scale use of natural gas for transportation. Diesel engines are extremely attractive in terms of energy efficiency, but expert judgment is divided on whether these engines will be able to meet strict emissions standards, even with reformulated fuel. The attractiveness of direct injection engines depends on their being able to meet strict emissions standards without losing their greater efficiency. Biofuels offer lower GHG emissions, are sustainable, and

  20. Course Content for Life Cycle Engineering and EcoDesign

    DEFF Research Database (Denmark)

    Jerswiet, Jack; Duflou, Joost; Dewulf, Wim

    2007-01-01

    There is a need to create an awareness of Life Cycle Engineering and EcoDesign in Engineering students. Topics covered in an LCE/EcoDesign course will create an awareness of environmental impacts, especially in other design course projects. This paper suggests that an awareness of product impact...... have the ultimate objective of decreasing the environmental impact of a design. It has been observed that 70% of product costs are decided at the design stage. This can be extended to environmental impact, where it can be observed that, the design is correct, at the beginning, the environmental impact...

  1. Battery energy storage systems life cycle costs case studies

    Energy Technology Data Exchange (ETDEWEB)

    Swaminathan, S.; Miller, N.F.; Sen, R.K. [SENTECH, Inc., Bethesda, MD (United States)

    1998-08-01

    This report presents a comparison of life cycle costs between battery energy storage systems and alternative mature technologies that could serve the same utility-scale applications. Two of the battery energy storage systems presented in this report are located on the supply side, providing spinning reserve and system stability benefits. These systems are compared with the alternative technologies of oil-fired combustion turbines and diesel generators. The other two battery energy storage systems are located on the demand side for use in power quality applications. These are compared with available uninterruptible power supply technologies.

  2. Technology and manufacturing process selection the product life cycle perspective

    CERN Document Server

    Pecas, Paulo; Silva, Arlindo

    2014-01-01

    This book provides specific topics intending to contribute to an improved knowledge on Technology Evaluation and Selection in a Life Cycle Perspectives. Although each chapter will present possible approaches and solutions, there are no recipes for success. Each reader will find his/her balance in applying the different topics to his/her own specific situation. Case studies presented throughout will help in deciding what fits best to each situation, but most of all any ultimate success will come out of the interplay between the available solutions and the specific problem or opportunity the reader is faced with.

  3. Life-cycle cost analysis of advanced design mixer pump

    Energy Technology Data Exchange (ETDEWEB)

    Hall, M.N., Westinghouse Hanford

    1996-07-23

    This analysis provides cost justification for the Advanced Design Mixer Pump program based on the cost benefit to the Hanford Site of 4 mixer pump systems defined in terms of the life-cycle cost.A computer model is used to estimate the total number of service hours necessary for each mixer pump to operate over the 20-year retrieval sequence period for single-shell tank waste. This study also considered the double-shell tank waste retrieved prior to the single-shell tank waste which is considered the initial retrieval.

  4. THE COST FOR THE ENTIRE LIFE CYCLE OF THE PRODUCT RESPECTING QUALITY STANDARDS

    OpenAIRE

    Mariana Man; Vladimir Modrak; Ioan Constantin Dima; Piotr Pachura

    2011-01-01

    This article presents issues concerning life cycle of products. Taking into account the limitation of the life cycle of products and strategic investments that require the use of certain technologies, the decision of setting forth a new product on the market should rely upon the costs of its life cycle.

  5. 10 CFR 436.42 - Evaluation of Life-Cycle Cost Effectiveness.

    Science.gov (United States)

    2010-01-01

    ... PROGRAMS Agency Procurement of Energy Efficient Products § 436.42 Evaluation of Life-Cycle Cost...) ENERGY STAR qualified and FEMP designated products may be assumed to be life-cycle cost-effective. (b) In making a determination that a covered product is not life-cycle cost-effective, an agency should rely on...

  6. The value of the exergetic life cycle assessment besides the LCA

    NARCIS (Netherlands)

    Cornelissen, Rene; Hirs, Gerard

    2002-01-01

    In this paper the value of the exergetic life cycle assessment (ELCA) has been analysed. The ELCA uses the framework of the life cycle assessment (LCA) and can be seen as the exergy analysis of a complete life cycle. The value of the ELCA besides the LCA has been discussed. It is shown that the ELCA

  7. Life cycle assessment of construction and demolition waste management

    DEFF Research Database (Denmark)

    Butera, Stefania; Christensen, Thomas Højlund; Astrup, Thomas Fruergaard

    2015-01-01

    Life cycle assessment (LCA) modelling of construction and demolition waste (C&DW) management was carried out. The functional unit was management of 1 Mg mineral, source separated C&DW, which is either utilised in road construction as a substitute for natural aggregates, or landfilled. The assessed...... environmental impacts included both non-toxic and toxic impact categories. The scenarios comprised all stages of the end-of-life management of C&DW, until final disposal of all residues. Leaching of inorganic contaminants was included, as was the production of natural aggregates, which was avoided because...... important contribution for most nontoxic impacts, accounting for 60-95 per cent of these impacts. Capital goods contributed with negligible impacts. Leaching played a critical role for the toxic categories, where landfilling had lower impacts than utilisation because of the lower levels of leachate per ton...

  8. Fuzzy Activity Based Life Cycle Costing For Repairable Equipment

    Directory of Open Access Journals (Sweden)

    Mulubrhan Freselam

    2016-01-01

    Full Text Available Life-cycle cost (LCC is the much known method used for decision making that considers all costs in the life of a system or equipment. Predicting LCCs is fraught with potential errors, owing to the uncertainty in future events, future costs, interest rates, and even hidden costs. These uncertainties have a direct impact on the decision making. Activity based LCC is used to identify the activities and cost drivers in acquisition, operation and maintenance phase. This activity based LCC is integrated with fuzzy set theory and interval mathematics to model these uncertainties. Day–Stout–Warren (DSW algorithm and the vertex method are then used to evaluate competing alternatives. A case of two pumps (Pump A and Pump B are taken and their LCC is analysed using the developed model. The equivalent annual cost of Pump B is greater than Pump A, which leads the decision maker to choose Pump A over Pump B.

  9. Development and infectious disease in hosts with complex life cycles.

    Directory of Open Access Journals (Sweden)

    Catherine L Searle

    Full Text Available Metamorphosis is often characterized by profound changes in morphology and physiology that can affect the dynamics of species interactions. For example, the interaction between a pathogen and its host may differ depending on the life stage of the host or pathogen. One pathogen that infects hosts with complex life cycles is the emerging fungal pathogen of amphibians, Batrachochytrium dendrobatidis (Bd. We sought to determine how conditions at the larval stage can affect variation in development and patterns of Bd infection across amphibian life stages. We used outdoor experimental mesocosms to simulate natural pond habitats and manipulated the presence of Bd, the larval density, and the number of host species in larvae of two co-occurring amphibian species (Rana cascadae and Pseudacris regilla. We found that infection differed between species throughout development; P. regilla consistently had higher infection severity compared to R. cascadae. Additionally, while up to 100% of larvae were infected, only 18.2% of R. cascadae and 81.5% of P. regilla were infected after metamorphosis. This indicates that amphibians have the ability to recover from Bd infection as they undergo metamorphosis. Higher larval densities in P. regilla led to a shorter larval period, and individuals with a shorter larval period had lower infection severity. This led to a trend where P. regilla larvae reared at high densities tended to have lower infection prevalence after metamorphosis. We also found that exposure to Bd increased larval mortality and prolonged the larval period in P. regilla, indicating that P. regilla are susceptible to the negative effects of Bd as larvae. This study demonstrates that host density, species composition, and pathogen exposure may all interact to influence development and infection in hosts with complex life cycles.

  10. Modeling Retirees' Life Satisfaction Levels: The Role of Recreational, Life Cycle and Socio-Environmental Elements.

    Science.gov (United States)

    Romsa, Gerald; And Others

    1985-01-01

    This study investigated satisfaction with retirement as a function of life cycle forces, socioenvironmental influences, and the degree of fulfillment of Maslow's hierarchy of needs through participation in recreational leisure activities. The findings from interviews with 300 retirees are discussed. (Author/MT)

  11. Total environmental impacts of biofuels from corn stover using a hybrid life cycle assessment model combining process life cycle assessment and economic input-output life cycle assessment.

    Science.gov (United States)

    Liu, Changqi; Huang, Yaji; Wang, Xinye; Tai, Yang; Liu, Lingqin; Liu, Hao

    2018-01-01

    Studies on the environmental analysis of biofuels by fast pyrolysis and hydroprocessing (BFPH) have so far focused only on the environmental impacts from direct emissions and have included few indirect emissions. The influence of ignoring some indirect emissions on the environmental performance of BFPH has not been well investigated and hence is not really understood. In addition, in order to avoid shifting environmental problems from one medium to another, a comprehensive assessment of environmental impacts caused by the processes must quantify the environmental emissions to all media (air, water, and land) in relation to each life cycle stage. A well-to-wheels assessment of the total environmental impacts resulting from direct emissions and indirect emissions of a BFPH system with corn stover is conducted using a hybrid life cycle assessment (LCA) model combining the economic input-output LCA and the process LCA. The Tool for the Reduction and Assessment of Chemical and other environmental Impacts (TRACI) has been used to estimate the environmental impacts in terms of acidification, eutrophication, global climate change, ozone depletion, human health criteria, photochemical smog formation, ecotoxicity, human health cancer, and human health noncancer caused by 1 MJ biofuel production. Taking account of all the indirect greenhouse gas (GHG) emissions, the net GHG emissions (81.8 g CO2 eq/MJ) of the biofuels are still less than those of petroleum-based fuels (94 g CO2 eq/MJ). Maize production and pyrolysis and hydroprocessing make major contributions to all impact categories except the human health criteria. All impact categories resulting from indirect emissions except eutrophication and smog air make more than 24% contribution to the total environmental impacts. Therefore, the indirect emissions are important and cannot be ignored. Sensitivity analysis has shown that corn stover yield and bio-oil yield affect the total environmental impacts of the biofuels

  12. Altair Lander Life Support: Design Analysis Cycles 4 and 5

    Science.gov (United States)

    Anderson, Molly; Curley, Su; Rotter, Henry; Stambaugh, Imelda; Yagoda, Evan

    2011-01-01

    Life support systems are a critical part of human exploration beyond low earth orbit. NASA s Altair Lunar Lander team is pursuing efficient solutions to the technical challenges of human spaceflight. Life support design efforts up through Design Analysis Cycle (DAC) 4 focused on finding lightweight and reliable solutions for the Sortie and Outpost missions within the Constellation Program. In DAC-4 and later follow on work, changes were made to add functionality for new requirements accepted by the Altair project, and to update the design as knowledge about certain issues or hardware matured. In DAC-5, the Altair project began to consider mission architectures outside the Constellation baseline. Selecting the optimal life support system design is very sensitive to mission duration. When the mission goals and architecture change several trade studies must be conducted to determine the appropriate design. Finally, several areas of work developed through the Altair project may be applicable to other vehicle concepts for microgravity missions. Maturing the Altair life support system related analysis, design, and requirements can provide important information for developers of a wide range of other human vehicles.

  13. Support for life-cycle product reuse in NASA's SSE

    Science.gov (United States)

    Shotton, Charles

    1989-01-01

    The Software Support Environment (SSE) is a software factory for the production of Space Station Freedom Program operational software. The SSE is to be centrally developed and maintained and used to configure software production facilities in the field. The PRC product TTCQF provides for an automated qualification process and analysis of existing code that can be used for software reuse. The interrogation subsystem permits user queries of the reusable data and components which have been identified by an analyzer and qualified with associated metrics. The concept includes reuse of non-code life-cycle components such as requirements and designs. Possible types of reusable life-cycle components include templates, generics, and as-is items. Qualification of reusable elements requires analysis (separation of candidate components into primitives), qualification (evaluation of primitives for reusability according to reusability criteria) and loading (placing qualified elements into appropriate libraries). There can be different qualifications for different installations, methodologies, applications and components. Identifying reusable software and related components is labor-intensive and is best carried out as an integrated function of an SSE.

  14. Life Cycle Cost Analysis of Ready Mix Concrete Plant

    Science.gov (United States)

    Topkar, V. M.; Duggar, A. R.; Kumar, A.; Bonde, P. P.; Girwalkar, R. S.; Gade, S. B.

    2013-11-01

    India, being a developing nation is experiencing major growth in its infrastructural sector. Concrete is the major component in construction. The requirement of good quality of concrete in large quantities can be fulfilled by ready mix concrete batching and mixing plants. The paper presents a technique of applying the value engineering tool life cycle cost analysis to a ready mix concrete plant. This will help an investor or an organization to take investment decisions regarding a ready mix concrete facility. No economic alternatives are compared in this study. A cost breakdown structure is prepared for the ready mix concrete plant. A market survey has been conducted to collect realistic costs for the ready mix concrete facility. The study establishes the cash flow for the ready mix concrete facility helpful in investment and capital generation related decisions. Transit mixers form an important component of the facility and are included in the calculations. A fleet size for transit mixers has been assumed for this purpose. The life cycle cost has been calculated for the system of the ready mix concrete plant and transit mixers.

  15. An Agent-Based Model of Institutional Life-Cycles

    Directory of Open Access Journals (Sweden)

    Manuel Wäckerle

    2014-08-01

    Full Text Available We use an agent-based model to investigate the interdependent dynamics between individual agency and emergent socioeconomic structure, leading to institutional change in a generic way. Our model simulates the emergence and exit of institutional units, understood as generic governed social structures. We show how endogenized trust and exogenously given leader authority influences institutional change, i.e., diversity in institutional life-cycles. It turns out that these governed institutions (destructure in cyclical patterns dependent on the overall evolution of trust in the artificial society, while at the same time, influencing this evolution by supporting social learning. Simulation results indicate three scenarios of institutional life-cycles. Institutions may, (1 build up very fast and freeze the artificial society in a stable but fearful pattern (ordered system; (2 exist only for a short time, leading to a very trusty society (highly fluctuating system; and (3 structure in cyclical patterns over time and support social learning due to cumulative causation of societal trust (complex system.

  16. Life Cycle Inventory Analysis of Recycling: Mathematical and Graphical Frameworks

    Directory of Open Access Journals (Sweden)

    Jun Nakatani

    2014-09-01

    Full Text Available A mathematical framework of the life cycle inventory (LCI analysis in life cycle assessment (LCA of recycling is systematically reviewed with the aid of graphical interpretation. First, the zero burden approach, which has been applied to LCI analyses of waste management systems, is theoretically justified in terms of relative comparison of waste management options. As recycling is a multi-functional system including the dual functions of waste management and secondary material production, the allocation issue needs to be handled in LCIs of recycling, and two forms of system expansion, i.e., the avoided burden and product basket approaches, have dominated to avoid the allocation problem. Then, it is demonstrated that conclusions derived from both approaches should mathematically be identical as far as system boundaries are correctly defined. A criticism against system expansion is also reviewed from the viewpoint of ambiguity of what-if scenarios. As an approach to this issue, market-based consequential LCA is discussed in the context of LCI analyses of open-loop recycling.

  17. Fungal parasitism: life cycle, dynamics and impact on cyanobacterial blooms.

    Science.gov (United States)

    Gerphagnon, Mélanie; Latour, Delphine; Colombet, Jonathan; Sime-Ngando, Télesphore

    2013-01-01

    Many species of phytoplankton are susceptible to parasitism by fungi from the phylum Chytridiomycota (i.e. chytrids). However, few studies have reported the effects of fungal parasites on filamentous cyanobacterial blooms. To investigate the missing components of bloom ecosystems, we examined an entire field bloom of the cyanobacterium Anabaena macrospora for evidence of chytrid infection in a productive freshwater lake, using a high resolution sampling strategy. A. macrospora was infected by two species of the genus Rhizosiphon which have similar life cycles but differed in their infective regimes depending on the cellular niches offered by their host. R. crassum infected both vegetative cells and akinetes while R. akinetum infected only akinetes. A tentative reconstruction of the developmental stages suggested that the life cycle of R. crassum was completed in about 3 days. The infection affected 6% of total cells (and 4% of akinètes), spread over a maximum of 17% of the filaments of cyanobacteria, in which 60% of the cells could be parasitized. Furthermore, chytrids may reduce the length of filaments of Anabaena macrospora significantly by "mechanistic fragmentation" following infection. All these results suggest that chytrid parasitism is one of the driving factors involved in the decline of a cyanobacteria blooms, by direct mortality of parasitized cells and indirectly by the mechanistic fragmentation, which could weaken the resistance of A. macrospora to grazing.

  18. Undergraduates' mental models about insect anatomy and insect life cycles

    Science.gov (United States)

    Diaz, Arlene Edith

    Educational studies focused on students' alternative conceptions have shown the importance of developing strategies to correct understanding. Identifying and comprehending student mental models are important since they may reflect alternate conceptions about scientific concepts. Mental models have been identified in various science education studies, but little is known about mental models undergraduates hold about insects. This research is significant because it identified mental models undergraduates have about insect anatomy and insect life cycles, exposed students to cognitive conflict by having them complete an online insect tutorial, and analyzed the effectiveness of this insect tutorial in correcting student understanding. An insect assessment was developed and administered pre- and post-instruction to probe students' mental models about insects. Different numbers of undergraduate students participated in different parts of the assessment; 276, 249, 166, and 58 students participated in the listing, drawing. definition, and life cycle parts of the assessment, respectively. The tutorial contained a variety of manipulated insect and non-insect images that challenged the students' understanding and generated cognitive conflict. This intervention guided students in replacing alternate conceptions with correct understanding. It was hypothesized that the tutorial would have a positive impact on student learning about insects. The results suggest that the tutorial had a positive impact on learning.

  19. Life Cycle Assessment of Lubricant Oil Plastic Containers in Brazil

    Directory of Open Access Journals (Sweden)

    Maria Clara Oliveira

    2017-04-01

    Full Text Available Brazil, like many emerging countries, has experienced a fast growth in the demand for automobiles in recent decades. This has produced a significant increase in the amount of hazardous waste to be disposed of, including used lubricant oil. Restrictive regulations are being used by many nations to deal with this problem, focusing on treatments, such as recycling, to avoid resource depletion. Specific rules for disposal of used lubricant oil already exist in various countries, including Brazil, but not for its containers. Using the life cycle assessment methodology, this article evaluates different management options for the destination of Lubricant Oil Plastic Containers (LOPCs, comparing recycling and incineration to disposal in an industrial landfill. Results show that reducing the proportion of LOPCs destined to the landfill has positive impacts in lowering the burdens caused in the life cycle of LOPCs. Incineration, which is not a technology used for destination of LOPCs in Brazil, proved to be a promising option when combined with recycling for treatment of this kind of waste. Combining different destinations is also a good option as long as economic, logistics and the environment are taken into consideration. The present paper concludes that emerging countries are able to manage hazardous waste provided that there is adequate legislation and political will along with cooperation from the private sector. This study can be helpful to the decision-making processes concerning hazardous waste, especially for industrial strategies and policy makers.

  20. Life Cycle Assessment for the Production of Oil Palm Seeds.

    Science.gov (United States)

    Muhamad, Halimah; Ai, Tan Yew; Khairuddin, Nik Sasha Khatrina; Amiruddin, Mohd Din; May, Choo Yuen

    2014-12-01

    The oil palm seed production unit that generates germinated oil palm seeds is the first link in the palm oil supply chain, followed by the nursery to produce seedling, the plantation to produce fresh fruit bunches (FFB), the mill to produce crude palm oil (CPO) and palm kernel, the kernel crushers to produce crude palm kernel oil (CPKO), the refinery to produce refined palm oil (RPO) and finally the palm biodiesel plant to produce palm biodiesel. This assessment aims to investigate the life cycle assessment (LCA) of germinated oil palm seeds and the use of LCA to identify the stage/s in the production of germinated oil palm seeds that could contribute to the environmental load. The method for the life cycle impact assessment (LCIA) is modelled using SimaPro version 7, (System for Integrated environMental Assessment of PROducts), an internationally established tool used by LCA practitioners. This software contains European and US databases on a number of materials in addition to a variety of European- and US-developed impact assessment methodologies. LCA was successfully conducted for five seed production units and it was found that the environmental impact for the production of germinated oil palm was not significant. The characterised results of the LCIA for the production of 1000 germinated oil palm seeds showed that fossil fuel was the major impact category followed by respiratory inorganics and climate change.

  1. Life cycle assessment of biodiesel production in China.

    Science.gov (United States)

    Liang, Sai; Xu, Ming; Zhang, Tianzhu

    2013-02-01

    This study aims to evaluate energy, economic, and environmental performances of seven categories of biodiesel feedstocks by using the mixed-unit input-output life cycle assessment method. Various feedstocks have different environmental performances, indicating potential environmental problem-shift. Jatropha seed, castor seed, waste cooking oil, and waste extraction oil are preferred feedstocks for biodiesel production in the short term. Positive net energy yields and positive net economic benefits of biodiesel from these four feedstocks are 2.3-52.0% of their life cycle energy demands and 74.1-448.4% of their economic costs, respectively. Algae are preferred in the long term mainly due to their less arable land demands. Special attention should be paid to potential environmental problems accompanying feedstock choice: freshwater use, ecotoxicity potentials, photochemical oxidation potential, acidification potential and eutrophication potential. Moreover, key processes are identified by sensitivity analysis to direct future technology improvements. Finally, supporting measures are proposed to optimize China's biodiesel development. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Fungal parasitism: life cycle, dynamics and impact on cyanobacterial blooms.

    Directory of Open Access Journals (Sweden)

    Mélanie Gerphagnon

    Full Text Available Many species of phytoplankton are susceptible to parasitism by fungi from the phylum Chytridiomycota (i.e. chytrids. However, few studies have reported the effects of fungal parasites on filamentous cyanobacterial blooms. To investigate the missing components of bloom ecosystems, we examined an entire field bloom of the cyanobacterium Anabaena macrospora for evidence of chytrid infection in a productive freshwater lake, using a high resolution sampling strategy. A. macrospora was infected by two species of the genus Rhizosiphon which have similar life cycles but differed in their infective regimes depending on the cellular niches offered by their host. R. crassum infected both vegetative cells and akinetes while R. akinetum infected only akinetes. A tentative reconstruction of the developmental stages suggested that the life cycle of R. crassum was completed in about 3 days. The infection affected 6% of total cells (and 4% of akinètes, spread over a maximum of 17% of the filaments of cyanobacteria, in which 60% of the cells could be parasitized. Furthermore, chytrids may reduce the length of filaments of Anabaena macrospora significantly by "mechanistic fragmentation" following infection. All these results suggest that chytrid parasitism is one of the driving factors involved in the decline of a cyanobacteria blooms, by direct mortality of parasitized cells and indirectly by the mechanistic fragmentation, which could weaken the resistance of A. macrospora to grazing.

  3. Revisiting the Life Cycle of Dung Fungi, Including Sordaria fimicola.

    Directory of Open Access Journals (Sweden)

    George Newcombe

    Full Text Available Dung fungi, such as Sordaria fimicola, generally reproduce sexually with ascospores discharged from mammalian dung after passage through herbivores. Their life cycle is thought to be obligate to dung, and thus their ascospores in Quaternary sediments have been interpreted as evidence of past mammalian herbivore activity. Reports of dung fungi as endophytes would seem to challenge the view that they are obligate to dung. However, endophyte status is controversial because surface-sterilization protocols could fail to kill dung fungus ascospores stuck to the plant surface. Thus, we first tested the ability of representative isolates of three common genera of dung fungi to affect plant growth and fecundity given that significant effects on plant fitness could not result from ascospores merely stuck to the plant surface. Isolates of S. fimicola, Preussia sp., and Sporormiella sp. reduced growth and fecundity of two of three populations of Bromus tectorum, the host from which they had been isolated. In further work with S. fimicola we showed that inoculations of roots of B. tectorum led to some colonization of aboveground tissues. The same isolate of S. fimicola reproduced sexually on inoculated host plant tissues as well as in dung after passage through sheep, thus demonstrating a facultative rather than an obligate life cycle. Finally, plants inoculated with S. fimicola were not preferred by sheep; preference had been expected if the fungus were obligate to dung. Overall, these findings make us question the assumption that these fungi are obligate to dung.

  4. Life cycle assessment of lithium sulfur battery for electric vehicles

    Science.gov (United States)

    Deng, Yelin; Li, Jianyang; Li, Tonghui; Gao, Xianfeng; Yuan, Chris

    2017-03-01

    Lithium-sulfur (Li-S) battery is widely recognized as the most promising battery technology for future electric vehicles (EV). To understand the environmental sustainability performance of Li-S battery on future EVs, here a novel life cycle assessment (LCA) model is developed for comprehensive environmental impact assessment of a Li-S battery pack using a graphene sulfur composite cathode and a lithium metal anode protected by a lithium-ion conductive layer, for actual EV applications. The Li-S battery pack is configured with a 61.3 kWh capacity to power a mid-size EV for 320 km range. The life cycle inventory model is developed with a hybrid approach, based on our lab-scale synthesis of the graphene sulfur composite, our lab fabrication of Li-S battery cell, and our industrial partner's battery production processes. The impacts of the Li-S battery are assessed using the ReCiPe method and benchmarked with those of a conventional Nickle-Cobalt-Manganese (NCM)-Graphite battery pack under the same driving distance per charge. The environmental impact assessment results illustrate that Li-S battery is more environmentally friendly than conventional NCM-Graphite battery, with 9%-90% lower impact. Finally, the improvement pathways for the Li-S battery to meet the USABC (U.S. Advanced Battery Consortium) targets are presented with the corresponding environmental impact changes.

  5. Evaluation of Life Cycle Assessment (LCA) for Roadway Drainage Systems.

    Science.gov (United States)

    Byrne, Diana M; Grabowski, Marta K; Benitez, Amy C B; Schmidt, Arthur R; Guest, Jeremy S

    2017-08-15

    Roadway drainage design has traditionally focused on cost-effectively managing water quantity; however, runoff carries pollutants, posing risks to the local environment and public health. Additionally, construction and maintenance incur costs and contribute to global environmental impacts. While life cycle assessment (LCA) can potentially capture local and global environmental impacts of roadway drainage and other stormwater systems, LCA methodology must be evaluated because stormwater systems differ from wastewater and drinking water systems to which LCA is more frequently applied. To this end, this research developed a comprehensive model linking roadway drainage design parameters to LCA and life cycle costing (LCC) under uncertainty. This framework was applied to 10 highway drainage projects to evaluate LCA methodological choices by characterizing environmental and economic impacts of drainage projects and individual components (basin, bioswale, culvert, grass swale, storm sewer, and pipe underdrain). The relative impacts of drainage components varied based on functional unit choice. LCA inventory cutoff criteria evaluation showed the potential for cost-based criteria, which performed better than mass-based criteria. Finally, the local aquatic benefits of grass swales and bioswales offset global environmental impacts for four impact categories, highlighting the need to explicitly consider local impacts (i.e., direct emissions) when evaluating drainage technologies.

  6. Mir Cooperative Solar Array Project Accelerated Life Thermal Cycling Test

    Science.gov (United States)

    Hoffman, David J.; Scheiman, David A.

    1996-01-01

    The Mir Cooperative Solar Array (MCSA) project was a joint U.S./Russian effort to build a photovoltaic (PV) solar array and deliver it to the Russian space station Mir. The MCSA will be used to increase the electrical power on Mir and provide PV array performance data in support of Phase 1 of the International Space Station. The MCSA was brought to Mir by space shuttle Atlantis in November 1995. This report describes an accelerated thermal life cycle test which was performed on two samples of the MCSA. In eight months time, two MCSA solar array 'mini' panel test articles were simultaneously put through 24,000 thermal cycles. There was no significant degradation in the structural integrity of the test articles and no electrical degradation, not including one cell damaged early and removed from consideration. The nature of the performance degradation caused by this one cell is briefly discussed. As a result of this test, changes were made to improve some aspects of the solar cell coupon-to-support frame interface on the flight unit. It was concluded from the results that the integration of the U.S. solar cell modules with the Russian support structure would be able to withstand at least 24,000 thermal cycles (4 years on-orbit). This was considered a successful development test.

  7. Power Systems Life Cycle Analysis Tool (Power L-CAT).

    Energy Technology Data Exchange (ETDEWEB)

    Andruski, Joel; Drennen, Thomas E.

    2011-01-01

    The Power Systems L-CAT is a high-level dynamic model that calculates levelized production costs and tracks environmental performance for a range of electricity generation technologies: natural gas combined cycle (using either imported (LNGCC) or domestic natural gas (NGCC)), integrated gasification combined cycle (IGCC), supercritical pulverized coal (SCPC), existing pulverized coal (EXPC), nuclear, and wind. All of the fossil fuel technologies also include an option for including carbon capture and sequestration technologies (CCS). The model allows for quick sensitivity analysis on key technical and financial assumptions, such as: capital, O&M, and fuel costs; interest rates; construction time; heat rates; taxes; depreciation; and capacity factors. The fossil fuel options are based on detailed life cycle analysis reports conducted by the National Energy Technology Laboratory (NETL). For each of these technologies, NETL's detailed LCAs include consideration of five stages associated with energy production: raw material acquisition (RMA), raw material transport (RMT), energy conversion facility (ECF), product transportation and distribution (PT&D), and end user electricity consumption. The goal of the NETL studies is to compare existing and future fossil fuel technology options using a cradle-to-grave analysis. The NETL reports consider constant dollar levelized cost of delivered electricity, total plant costs, greenhouse gas emissions, criteria air pollutants, mercury (Hg) and ammonia (NH3) emissions, water withdrawal and consumption, and land use (acreage).

  8. Developing a dynamic life cycle greenhouse gas emission inventory for wood construction for two different end-of-life scenarios

    Science.gov (United States)

    Richard D. Bergman; James Salazar; Scott Bowe

    2012-01-01

    Static life cycle assessment does not fully describe the carbon footprint of construction wood because of carbon changes in the forest and product pools over time. This study developed a dynamic greenhouse gas (GHG) inventory approach using US Forest Service and life-cycle data to estimate GHG emissions on construction wood for two different end-of-life scenarios....

  9. Life-history tradeoffs and reproductive cycles in Spotted Owls

    Science.gov (United States)

    Stoelting, Ricka E.; Gutierrez, R.J.; Kendall, William L.; Peery, M. Zachariah

    2015-01-01

    The study of tradeoffs among life-history traits has long been key to understanding the evolution of life-history strategies. However, more recently, evolutionary ecologists have realized that reproductive costs have the potential to influence population dynamics. Here, we tested for costs of reproduction in the California Spotted Owl (Strix occidentalis occidentalis), and assessed whether costs of reproduction in year t − 1 on reproduction in year t could be responsible for regionally synchronized biennial cycles in reproductive output. Logistic regression analysis and multistate mark–recapture models with state uncertainty revealed that breeding reduced the likelihood of reproducing in the subsequent year by 16% to 38%, but had no influence on subsequent survival. We also found that costs of reproduction in year t − 1 were correlated with climatic conditions in year t, with evidence of higher costs during the dry phase of the El Niño–Southern Oscillation. Using a simulation-based population model, we showed that strong reproductive costs had the potential to create biennial cycles in population-level reproductive output; however, estimated costs of reproduction appeared to be too small to explain patterns observed in Spotted Owls. In the absence of strong reproductive costs, we hypothesize that observed natural cycles in the reproductive output of Spotted Owls are related to as-yet-unmeasured, regionally concordant fluctuations in environmental conditions or prey resources. Despite theoretical evidence for demographic effects, our analyses illustrate that linking tradeoffs to actual changes in population processes will be challenging because of the potential confounding effects of individual and environmental variation.

  10. To be or not to be alive: How recent discoveries challenge the traditional definitions of viruses and life.

    Science.gov (United States)

    Forterre, Patrick

    2016-10-01

    Three major discoveries have recently profoundly modified our perception of the viral world: molecular ecologists have shown that viral particles are more abundant than cells in natural environments; structural biologists have shown that some viruses from the three domains of life, Bacteria, Eukarya and Archaea, are evolutionarily related, and microbiologists have discovered giant viruses that rival with cells in terms of size and gene content. I discuss here the scientific and philosophical impact of these discoveries on the debates over the definition, nature (living or not), and origin of viruses. I suggest that viruses have often been considered non-living, because they are traditionally assimilated to their virions. However, the term virus describes a biological process and should integrate all aspects of the viral reproduction cycle. It is especially important to focus on the intracellular part of this cycle, the virocell, when viral information is actively expressed and reproduced, allowing the emergence of new viral genes. The virocell concept theoretically removes roadblocks that prevent defining viruses as living organisms. However, defining a "living organism" remains challenging, as indicated by the case of organelles that evolved from intracellular bacteria. To bypass this problem, I suggest considering that all biological entities that actively participate in the process of life are living. Copyright © 2016. Published by Elsevier Ltd.

  11. Life cycle management and assessment: approaches and visions towards sustainable manufacturing

    DEFF Research Database (Denmark)

    Westkämper, Engelbert; Alting, Leo; Arndt, Günther

    2001-01-01

    and optimizes the interaction of product design, manufacturing and life cycle activities. The goal of this approach is to protect resources and maximize effectiveness by means of life cycle assessment, product data management, technical support and, last but not least, life cycle costing. This paper shows......(Enhanced version of keynote paper from Annals of the CIRP Vol. 43/2000) Thinking in terms of product life cycles is one of the challenges facing manufacturers today: efforts to increase efficiency throughout the life cycle do not only mean extended responsibility of the parties concerned...

  12. Life cycle management and assessment: approaches and visions towards sustainable manufacturing

    DEFF Research Database (Denmark)

    Westkämper, Engelbert; Alting, Leo; Arndt, Günther

    2000-01-01

    Thinking in terms of product life cycles is one of the challenges facing manufacturers today: efforts to increase efficiency throughout the life cycle do not only mean extended responsibility of the parties concerned. Economically successful business areas can also be explored. Whether new service...... concepts are required, new regulations have been passed or consumer values are changing, the differences between business areas are disappearing. Life cycle management (LCM) considers the product life cycle as a whole and optimizes the interaction of product design, manufacturing and life cycle activities...

  13. Galactic cycles and their relationship to life on earth

    Energy Technology Data Exchange (ETDEWEB)

    Olson, A.P.

    1984-05-01

    This paper draws attention to episodic events in the geologic time scale of the evolution of life on earth, and discusses potentially cyclic behavior relative to galactic structure. The question is a simple one: Do galactic processes affect the solar system. It is known that the sun is moving at about 220 +- 15 km/sec at a distance of about 8.5 +- 0.5 kpc from the galactic center. This motion, if circular and unperturbed, implies an orbital period of 237 +- 21 My for the solar system around the galaxy. The Milky Way also evidences structure typically interpreted as spiral arms, in the distribution of gas clouds in its central plane. The relative motion of the spiral arms, known as the pattern speed, is about 2/3 that of the sun. Consequently the solar system gains upon and passes through all the structure in its orbital plane once in three rotations or approx.700 My. If this structure is persistent over times longer than 700 My, it is clear that the interaction (if any) can be called cyclic. Furthermore, if there is any sub-structure or inner pattern to the 700 My cycle, it may show up as higher harmonics. Age estimates for the Milky Way are 12-15 By, or approx.17 to 22 structure cycles of 0.70 By. It seems not unreasonable to expect some persistence of a pattern over a few structure cycles. It must be noted that the pattern speed is quite uncertain. Perhaps geophysical evidence can be used to improve on the nominally 700 My structure cycle which is assumed in this paper. 16 references, 8 figures.

  14. Towards Life Cycle Sustainability Assessment of Alternative Passenger Vehicles

    Directory of Open Access Journals (Sweden)

    Nuri Cihat Onat

    2014-12-01

    Full Text Available Sustainable transportation and mobility are key components and central to sustainable development. This research aims to reveal the macro-level social, economic, and environmental impacts of alternative vehicle technologies in the U.S. The studied vehicle technologies are conventional gasoline, hybrid, plug-in hybrid with four different all-electric ranges, and full battery electric vehicles (BEV. In total, 19 macro level sustainability indicators are quantified for a scenario in which electric vehicles are charged through the existing U.S. power grid with no additional infrastructure, and an extreme scenario in which electric vehicles are fully charged with solar charging stations. The analysis covers all life cycle phases from the material extraction, processing, manufacturing, and operation phases to the end-of-life phases of vehicles and batteries. Results of this analysis revealed that the manufacturing phase is the most influential phase in terms of socio-economic impacts compared to other life cycle phases, whereas operation phase is the most dominant phase in the terms of environmental impacts and some of the socio-economic impacts such as human health and economic cost of emissions. Electric vehicles have less air pollution cost and human health impacts compared to conventional gasoline vehicles. The economic cost of emissions and human health impact reduction potential can be up to 45% and 35%, respectively, if electric vehicles are charged through solar charging stations. Electric vehicles have potential to generate income for low and medium skilled workers in the U.S. In addition to quantified sustainability indicators, some sustainability metrics were developed to compare relative sustainability performance alternative passenger vehicles. BEV has the lowest greenhouse gas emissions and ecological land footprint per $ of its contribution to the U.S. GDP, and has the lowest ecological footprint per unit of its energy consumption. The

  15. REPORT ON ACTIVITY OF TASK FORCE 1 IN THE LIFE CYCLE INVENTORY PROGRAMME: DATA REGISTRY - GLOBAL LIFE CYCLE INVENTORY DATA RESOURCES

    Science.gov (United States)

    This paper presents a summary of the findings of a report prepared by Task Force 1 of the UNEP/SETAC Life Cycle Initiative on the available Life Cycle Inventory (LCI) databases around the world. An update of a previous summary prepared in May 2002 by Norris and Notten, the repor...

  16. Technology sourcing over the technology life cycle : A study about the moderating effect of the technology life cycle on the relation between technology sourcing and firm performance

    NARCIS (Netherlands)

    Stolwijk, C.C.M.

    2012-01-01

    How do external and internal technology sourcing influence the innovative and market performance of firms over the technology life-cycle? The impact of technology sourcing on firm performance during different phases of the technology life cycle represents a gap in academic literature. Practically,

  17. Assessment of Environmental and Economic Impacts of Vine-Growing Combining Life Cycle Assessment, Life Cycle Costing and Multicriterial Analysis

    Directory of Open Access Journals (Sweden)

    Giacomo Falcone

    2016-08-01

    Full Text Available The wine sector is going through a significant evolution dealing with the challenges of competition issues in international markets and with necessary commitments to sustainability improvement. In the wine supply chain, the agricultural phase represents a potential source of pollution and costs. From the farmers’ point of view, these contexts require them to be more attentive and find a compromise among environmental benefits, economic benefits, and costs linked to farming practices. This paper aims to make a sustainability assessment of different wine-growing scenarios located in Calabria (Southern Italy that combines conflicting insights, i.e., environmental and economic ones, by applying Life Cycle Assessment (LCA and Life Cycle Costing (LCC to identify the main hotspots and select the alternative scenarios closest to the ideal solution through the VIKOR multicriteria method. In particular, the latter allowed us to obtain synthetic indices for a two-dimensional sustainability assessment. Conventional practices associated to the espalier training system represent the best compromise from both environmental and economic points of view, due to the higher yield per hectare. The choices regarding Functional Unit (FU and indicators were shown to have a high influence on results.

  18. Comparative life cycle assessment and life cycle costing of four disposal scenarios for used polyethylene terephthalate bottles in Mauritius.

    Science.gov (United States)

    Foolmaun, Rajendra Kumar; Ramjeeawon, Toolseeram

    2012-09-01

    The annual rise in population growth coupled with the flourishing tourism industry in Mauritius has lead to a considerable increase in the amount of solid waste generated. In parallel, the disposal of non-biodegradable wastes, especially plastic packaging and plastic bottles, has also shown a steady rise. Improper disposal of used polyethylene terephthalate (PET) bottles constitutes an eyesore to the environmental landscape and is a threat to the flourishing tourism industry. It is of utmost importance, therefore, to determine a suitable disposal method for used PET bottles which is not only environmentally efficient but is also cost effective. This study investigated the environmental impacts and the cost effectiveness of four selected disposal alternatives for used PET bottles in Mauritius. The four disposal routes investigated were: 100% landfilling; 75% incineration with energy recovery and 25% landfilling; 40% flake production (partial recycling) and 60% landfilling; and 75% flake production and 25% landfilling. Environmental impacts of the disposal alternatives were determined using ISO standardized life cycle assessment (LCA) and with the support of SimaPro 7.1 software. Cost effectiveness was determined using life cycle costing (LCC). Collected data were entered into a constructed Excel-based model to calculate the different cost categories, Net present values, damage costs and payback periods. LCA and LCC results indicated that 75% flake production and 25% landfilling was the most environmentally efficient and cost-effective disposal route for used PET bottles in Mauritius.

  19. Comparison of algae cultivation methods for bioenergy production using a combined life cycle assessment and life cycle costing approach.

    Science.gov (United States)

    Resurreccion, Eleazer P; Colosi, Lisa M; White, Mark A; Clarens, Andres F

    2012-12-01

    Algae are an attractive energy source, but important questions still exist about the sustainability of this technology on a large scale. Two particularly important questions concern the method of cultivation and the type of algae to be used. This present study combines elements of life cycle analysis (LCA) and life cycle costing (LCC) to evaluate open pond (OP) systems and horizontal tubular photobioreactors (PBRs) for the cultivation of freshwater (FW) or brackish-to-saline water (BSW) algae. Based on the LCA, OPs have lower energy consumption and greenhouse gas emissions than PBRs; e.g., 32% less energy use for construction and operation. According to the LCC, all four systems are currently financially unattractive investments, though OPs are less so than PBRs. BSW species deliver better energy and GHG performance and higher profitability than FW species in both OPs and PBRs. Sensitivity analyses suggest that improvements in critical cultivation parameters (e.g., CO(2) utilization efficiency or algae lipid content), conversion parameters (e.g., anaerobic digestion efficiency), and market factors (e.g., costs of CO(2) and electricity, or sale prices for algae biodiesel) could alter these results. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Cycles Tipping the Scale between Death and Survival (=``Life")

    Science.gov (United States)

    Halberg, F.; Cornélissen, G.; Sothern, R. B.; Katinas, G. S.; Schwartzkopff, O.; Otsuka, K.

    the wider cosmos, cosmoheliogeomagnetics, ultraviolet flux, gravitation, acoustics and others. Nonphotics, a set of in part transdisciplinarily-novel spectral components, can be intermittent; when present, they coexist and compete with signatures of photic cycles, monitored, e.g., in BP and HR. Nonphotics of, e.g., about (˜) 1 week (circaseptans) and ˜17 months (transyears), characterize mood and performance, modulate and sometimes override society's (photic) schedules, even in dying suddenly either unintentionally or by one's own will or at the hand of others. Nonphotics persist, but are damped in physiology or in terrorism, when their environmental counterpart is not detected. Their elucidation provides information on how a set of cycles covering 18 orders of magnitude in the frequency domain of the biosphere bears on the question ``What is life?": a resonance of the biosphere with periods of its environment constitutes life itself.

  1. Life cycle assessment of an SOFC/GT process

    Energy Technology Data Exchange (ETDEWEB)

    Olausson, Pernilla

    1999-06-01

    For the last few years much effort has been put into the research on different kinds of fuel cells, since these are considered to be both an efficient and environment friendly way to convert energy. The fuel cell studied here is the solid oxide fuel cell (SOFC) that works at a high temperature (800-1000 C) and today achieves a stand-alone electric efficiency of approximately 50%. When integrating the SOFC in a gas turbine process (SOFC/GT process) an efficiency of 70-75% can be reached. The SOFC and the SOFC/GT process are considered to be environment friendly regarding the discharges during operation. Especially formation of nitrogen oxides (NO{sub x}) is low since the SOFC temperatures are low compared to NO{sub x} formation temperatures. To study the whole environmental impact of the SOFC/GT process a life cycle assessment (LCA) is carried out to find the `hot spots` in the process` life cycle. Since the SOFC/GT process is under development today the collected data are mainly from literature and articles based on laboratory results. When performing the LCA only the SOFC-module and the gas turbine are included. A collection of data of all processes included, extraction of minerals, processing of raw material, production of the components, operation of the SOFC/GT process and transports between all these processes. These data are then added up and weighted in impact categories to evaluate the total environmental impact of the SOFC/GT process. All these steps are performed according to the ISO 14040-series. The stand-alone most contributing phase during the life cycle of the SOFC/GT process was found to be the production of the SOFC. All processes during the production of the SOFC are carried out under laboratory circumstances, which require more energy and materials than if the processes were commercialised and optimised. For the SOFC/GT process to be competitive with other energy converting processes regarding the discharges of emissions to the air, the use of

  2. The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy

    Directory of Open Access Journals (Sweden)

    Ketaki Ganti

    2015-07-01

    Full Text Available Cancer-causing HPV E6 oncoproteins are characterized by the presence of a PDZ binding motif (PBM at their extreme carboxy terminus. It was long thought that this region of E6 had a sole function to confer interaction with a defined set of cellular substrates. However, more recent studies have shown that the E6 PBM has a complex pattern of regulation, whereby phosphorylation within the PBM can regulate interaction with two classes of cellular proteins: those containing PDZ domains and the members of the 14-3-3 family of proteins. In this review, we explore the roles that the PBM and its ligands play in the virus life cycle, and subsequently how these can inadvertently contribute towards the development of malignancy. We also explore how subtle alterations in cellular signal transduction pathways might result in aberrant E6 phosphorylation, which in turn might contribute towards disease progression.

  3. An algorithm for a decomposition of weighted digraphs: with applications to life cycle analysis in ecology.

    Science.gov (United States)

    Sun, L; Wang, M

    2007-02-01

    In the analysis of organism life cycles in ecology, comparisons of life cycles between species or between different types of life cycles within species are frequently conducted. In matrix population models, partitioning of the elasticity matrix is used to quantify the separate contributions of different life cycles to the population growth rate. Such partition is equivalent to a decomposition of the life cycle graph of the population. A graph theoretic spanning tree method to carry out the decomposition was formalized by Wardle [Ecology 79(7), 2539-2549 (1998)]. However there are difficulties in realizing a suitable decomposition for complex life histories using the spanning-tree method. One of the problems is the occurrence of life cycles that contain contradictory directions that defy biological interpretation. We propose an algorithmic approach for decomposing a directed, weighted graph. The graph is to be decomposed into two parts. The first part is a set of simple cycles that contain no contradictory directions and that consist of edges of equal weight. The second part of the decomposition is a subgraph in which no such simple cycles are obtainable. When applied to life cycle analysis in ecology, the proposed method will guarantee a complete decomposition of the life cycle graph into individual life cycles containing no contradictory directions.

  4. End-of-life flows of multiple cycle consumer products.

    Science.gov (United States)

    Tsiliyannis, C A

    2011-11-01

    Explicit expressions for the end-of-life flows (EOL) of single and multiple cycle products (MCPs) are presented, including deterministic and stochastic EOL exit. The expressions are given in terms of the physical parameters (maximum lifetime, T, annual cycling frequency, f, number of cycles, N, and early discard or usage loss). EOL flows are also obtained for hi-tech products, which are rapidly renewed and thus may not attain steady state (e.g., electronic products, passenger cars). A ten-step recursive procedure for obtaining the dynamic EOL flow evolution is proposed. Applications of the EOL expressions and the ten-step procedure are given for electric household appliances, industrial machinery, tyres, vehicles and buildings, both for deterministic and stochastic EOL exit, (normal, Weibull and uniform exit distributions). The effect of the physical parameters and the stochastic characteristics on the EOL flow is investigated in the examples: it is shown that the EOL flow profile is determined primarily by the early discard dynamics; it also depends strongly on longevity and cycling frequency: higher lifetime or early discard/loss imply lower dynamic and steady state EOL flows. The stochastic exit shapes the overall EOL dynamic profile: Under symmetric EOL exit distribution, as the variance of the distribution increases (uniform to normal to deterministic) the initial EOL flow rise becomes steeper but the steady state or maximum EOL flow level is lower. The steepest EOL flow profile, featuring the highest steady state or maximum level, as well, corresponds to skew, earlier shifted EOL exit (e.g., Weibull). Since the EOL flow of returned products consists the sink of the reuse/remanufacturing cycle (sink to recycle) the results may be used in closed loop product lifecycle management operations for scheduling and sizing reverse manufacturing and for planning recycle logistics. Decoupling and quantification of both the full age EOL and of the early discard flows is

  5. Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection

    Science.gov (United States)

    Fan, Ying; Mok, Chris Ka-Pun; Chan, Michael Chi Wai; Zhang, Yang; Nal, Béatrice; Kien, François; Bruzzone, Roberto; Sanyal, Sumana

    2017-01-01

    To identify new host factors that modulate the replication of influenza A virus, we performed a yeast two-hybrid screen using the cytoplasmic tail of matrix protein 2 from the highly pathogenic H5N1 strain. The screen revealed a high-score interaction with cyclin D3, a key regulator of cell cycle early G1 phase. M2-cyclin D3 interaction was validated through GST pull-down and recapitulated in influenza A/WSN/33-infected cells. Knockdown of Ccnd3 by small interfering RNA significantly enhanced virus progeny titers in cell culture supernatants. Interestingly, the increase in virus production was due to cyclin D3 deficiency per se and not merely a consequence of cell cycle deregulation. A combined knockdown of Ccnd3 and Rb1, which rescued cell cycle progression into S phase, failed to normalize virus production. Infection by influenza A virus triggered redistribution of cyclin D3 from the nucleus to the cytoplasm, followed by its proteasomal degradation. When overexpressed in HEK 293T cells, cyclin D3 impaired binding of M2 with M1, which is essential for proper assembly of progeny virions, lending further support to its role as a putative restriction factor. Our study describes the identification and characterization of cyclin D3 as a novel interactor of influenza A virus M2 protein. We hypothesize that competitive inhibition of M1-M2 interaction by cyclin D3 impairs infectious virion formation and results in attenuated virus production. In addition, we provide mechanistic insights into the dynamic interplay of influenza virus with the host cell cycle machinery during infection. PMID:28130444

  6. Life cycle assessment of construction and demolition waste management

    Energy Technology Data Exchange (ETDEWEB)

    Butera, Stefania, E-mail: stbu@teknologisk.dk; Christensen, Thomas H.; Astrup, Thomas F.

    2015-10-15

    Highlights: • LCA of C&DW utilisation in road vs. C&DW landfilling. • C&DW utilisation in road better than landfilling for most categories. • Transportation is the most important process in non-toxic impact categories. • Leaching of oxyanions is the critical process in toxic impact categories. • Modelling of Cr fate in the subsoil is highly influential to the results. - Abstract: Life cycle assessment (LCA) modelling of construction and demolition waste (C&DW) management was carried out. The functional unit was management of 1 Mg mineral, source separated C&DW, which is either utilised in road construction as a substitute for natural aggregates, or landfilled. The assessed environmental impacts included both non-toxic and toxic impact categories. The scenarios comprised all stages of the end-of-life management of C&DW, until final disposal of all residues. Leaching of inorganic contaminants was included, as was the production of natural aggregates, which was avoided because of the use of C&DW. Typical uncertainties related to contaminant leaching were addressed. For most impact categories, utilisation of C&DW in road construction was preferable to landfilling; however, for most categories, utilisation resulted in net environmental burdens. Transportation represented the most important contribution for most nontoxic impacts, accounting for 60–95 per cent of these impacts. Capital goods contributed with negligible impacts. Leaching played a critical role for the toxic categories, where landfilling had lower impacts than utilisation because of the lower levels of leachate per ton of C&DW reaching the groundwater over a 100-year perspective. Leaching of oxyanions (As, V and Sb) was critical with respect to leaching. Typical experimental uncertainties in leaching data did not have a pivotal influence on the results; however, accounting for Cr immobilisation in soils as part of the impact assessment was critical for modelling the leaching impacts. Compared

  7. Life cycle assessment of construction and demolition waste management.

    Science.gov (United States)

    Butera, Stefania; Christensen, Thomas H; Astrup, Thomas F

    2015-10-01

    Life cycle assessment (LCA) modelling of construction and demolition waste (C&DW) management was carried out. The functional unit was management of 1 Mg mineral, source separated C&DW, which is either utilised in road construction as a substitute for natural aggregates, or landfilled. The assessed environmental impacts included both non-toxic and toxic impact categories. The scenarios comprised all stages of the end-of-life management of C&DW, until final disposal of all residues. Leaching of inorganic contaminants was included, as was the production of natural aggregates, which was avoided because of the use of C&DW. Typical uncertainties related to contaminant leaching were addressed. For most impact categories, utilisation of C&DW in road construction was preferable to landfilling; however, for most categories, utilisation resulted in net environmental burdens. Transportation represented the most important contribution for most nontoxic impacts, accounting for 60-95 per cent of these impacts. Capital goods contributed with negligible impacts. Leaching played a critical role for the toxic categories, where landfilling had lower impacts than utilisation because of the lower levels of leachate per ton of C&DW reaching the groundwater over a 100-year perspective. Leaching of oxyanions (As, V and Sb) was critical with respect to leaching. Typical experimental uncertainties in leaching data did not have a pivotal influence on the results; however, accounting for Cr immobilisation in soils as part of the impact assessment was critical for modelling the leaching impacts. Compared with the overall life cycle of building and construction materials, leaching emissions were shown to be potentially significant for toxicity impacts, compared with contributions from production of the same materials, showing that end-of-life impacts and leaching should not be disregarded when assessing environmental impacts from construction products and materials. CO2 uptake in the C

  8. Valuation methods within the framework of life cycle assessment

    Energy Technology Data Exchange (ETDEWEB)

    Finnveden, G.

    1996-05-01

    Life Cycle Assessment Valuation methods are discussed. Different approaches for valuation are discussed as well as presently available valuation methods in relation to: * the values involved in the valuation, * the LCA framework, and * different applications of LCA. Among the conclusions are: * ethical and ideological valuations are involved not only when applying valuation weighting factors, but also when choosing valuation method and also when choosing whether to perform a valuation weighting or not, * it can be questioned whether straight distance-to-target methods are valuation methods, * it is still an open question whether presently available valuation methods produce meaningful and reliable information, * further development of quantitative valuation methods could concentrate both on different types of monetarisation methods and panel methods, * in many applications of LCA, the expected result is an identification of critical areas rather than a one-dimensional score, reducing the need for valuation methods. 88 refs, 3 figs, 4 tabs

  9. Life cycle guideline of petrochemical plant underground piping system

    Directory of Open Access Journals (Sweden)

    Shih Jeng-Ywan

    2017-01-01

    Full Text Available According to statistics of petrochemical plant disaster, the type of underground pipeline leakage is the highest proportion, for example, Kaohsiung gas explosion in 2014 is a typical case. Therefore, improvement strategy of petrochemical plant underground piping system from both engineering and management becomes an important issue. Through reviewing regulations as well as surveying questionnaire, including kinds of piping materials, 3D drawing files, operation procedures, information sharing, etc., the findings show lack contact of integrated management with engineering executive and insufficient technical requirements are major defects. Overviewing current problems of domestic petrochemical plant underground piping system management, and comparing to international criteria and specifications, this research focuses on the of piping design, construction, operations, maintenance, and inspection. Then management procedures and engineering technical feasibility strategies are suggested. In addition, the proposed life cycle guideline in order to reduce the disaster incidence of petrochemical plant underground pipelines.

  10. Evaluation of life cycle inventory data for recycling systems

    DEFF Research Database (Denmark)

    Brogaard, Line Kai-Sørensen; Damgaard, Anders; Jensen, Morten Bang

    2014-01-01

    This paper reviews databases on material recycling (primary as well as secondary production) used in life cycle assessments (LCA) of waste management systems. A total of 366 datasets, from 1980 to 2010 and covering 14 materials, were collected from databases and reports. Totals for CO2-equivalent...... emissions were compared to illustrate variations in the data. It was hypothesised that emissions from material production and the recycling industry had decreased over time due to increasing regulation, energy costs and process optimisation, but the reported datasets did not reveal such a general trend...... the primary production of newsprint, HDPE and glass were 238%, 443% and 452%, respectively. For steel and aluminium the differences were 1761% and 235%, respectively. There is a severe lack of data for some recycled materials; for example, only one dataset existed for secondary cardboard. The study shows...

  11. Life cycle assessment of nanoadsorbents at early stage technological development

    DEFF Research Database (Denmark)

    Kazemi, Ali; Bahramifar, Nader; Heydari, Akbar

    2018-01-01

    the process of the functionalization of nanoadsorbents leads to the increase of the adsorption capacity of nanoadsorbents, it is also paired with a significant enhancement of negative environmental impacts. The results of t-test comparing the cradle-to-use life cycle impacts of studied impact categories for 1......Increasing pressure to the environment due to human activities manifests the necessity of applying new approaches to determine the environmental impact of a new product before scale-up. Nanoadsorbents as an emerging product and a special application of nanomaterial play an important role...... in the control and removal of environmental pollutants. This application is still an emerging technology at the early stages of development. Hence, the heart of this study enables an environmental assessment of nanoadsorbents as an emerging product. In addition, the environmental impacts of synthesized...

  12. Capabilities For Modelling Of Conversion Processes In Life Cycle Assessment

    DEFF Research Database (Denmark)

    Damgaard, Anders; Zarrin, Bahram; Tonini, Davide

    Life cycle assessment was traditionally used for modelling of product design and optimization. This is also seen in the conventional LCA software which is optimized for the modelling of single materials streams of a homogeneous nature that is assembled into a final product. There has therefore been...... little focus on the chemical composition of the functional flows, as flows in the models have mainly been tracked on a mass basis, as emphasis was the function of the product and not the chemical composition of said product. Conversely, in modelling of environmental technologies, such as wastewater...... considering how the biochemical parameters change through a process chain. A good example of this is bio-refinery processes where different residual biomass products are converted through different steps into the final energy product. Here it is necessary to know the stoichiometry of the different products...

  13. Life cycle assessment and the resilience of product systems

    DEFF Research Database (Denmark)

    Pizzol, Massimo

    2015-01-01

    Resilience is the capacity of systems to withstand and recover from disturbance, depends on the structure and architecture of a system, and plays a key role for the sustainability of complex systems. Despite its importance, resilience is not explicitly taken into account by studies of life cycle...... assessment (LCA), which main objective is determining the eco-efficiency of a product system with limited focus on its structure. The question is whether a product system which structure is improved or designed to be more resilient will result in being not only inefficient, but also eco-inefficient, when...... assessed by means of LCA. This study proposes a theoretical modelling approach to compare vulnerable and resilient product systems within the framework of LCA, consisting of assessment of disturbance and system expansion. Examples are provided where the theory is made operational. The structure...

  14. Reports of violence against women in different life cycles.

    Science.gov (United States)

    Leite, Maísa Tavares de Souza; Figueiredo, Maria Fernanda Santos; Dias, Orlene Veloso; Vieira, Maria Aparecida; Souza e Souza, Luís Paulo; Mendes, Danilo Cangussu

    2014-01-01

    to analyze the reports and factors associated with violence against women. this was a cross-sectional, exploratory and analytical study with information about the cases of reported violence, extracted from the Civil Police Report Bulletin, in a mid-sized city in Minas Gerais, Brazil. out of the 7,487 reports of violence against women, it was found that 44.6% of the cases were threats, 28.5% aggression, 25.1% bodily injury, 1.1% rape, and 0.7% some other type of injury. In the bivariate analysis, a higher number of cases (p=0.000) committed by partners was evidenced, for all kinds of violence except for rape. Children, adolescents and adults experienced violence by partners, followed by family members. Regarding older women, violence was committed by family members. there is the need for programs to be established to prevent violence against women in various sectors of society, permeating the life cycle.

  15. Life cycle of Coitocoecum plagiorchis (Trematoda: Digenea: Opecoelidae).

    Science.gov (United States)

    Yoshida, Reiko; Urabe, Misako

    2005-12-01

    The life cycle of Coitocoecum plagiorchis Ozaki, 1926 (Coitocaecum is an incorrect subsequent spelling) was studied in the field and laboratory. The study was conducted at the Futatsu River and the Chikugo River, Kyushu, Japan. Adults of C. plagiorchis were obtained from fishes Coreoperca kawamebari, Rhinogobius spp. and Odontobutis obscura. Cotylomicrocercous cercariae with a two-point stylet (=Cercaria distyloides Faust, 1924) were detected in pleurocerid snails (Semisulcospira spp.). Metacercariae with a cyclocoel were obtained from shrimp (Neocaridina denticulata). The cercariae were experimentally exposed to the shrimp, and subsequently metacercariae with a cyclocoel were recovered from the shrimp within 24 days after exposure. These metacercariae were identified as C. plagiorchis. The sporocysts, cercariae, metacercariae and adults are briefly described.

  16. Illustrating anticipatory life cycle assessment for emerging photovoltaic technologies.

    Science.gov (United States)

    Wender, Ben A; Foley, Rider W; Prado-Lopez, Valentina; Ravikumar, Dwarakanath; Eisenberg, Daniel A; Hottle, Troy A; Sadowski, Jathan; Flanagan, William P; Fisher, Angela; Laurin, Lise; Bates, Matthew E; Linkov, Igor; Seager, Thomas P; Fraser, Matthew P; Guston, David H

    2014-09-16

    Current research policy and strategy documents recommend applying life cycle assessment (LCA) early in research and development (R&D) to guide emerging technologies toward decreased environmental burden. However, existing LCA practices are ill-suited to support these recommendations. Barriers related to data availability, rapid technology change, and isolation of environmental from technical research inhibit application of LCA to developing technologies. Overcoming these challenges requires methodological advances that help identify environmental opportunities prior to large R&D investments. Such an anticipatory approach to LCA requires synthesis of social, environmental, and technical knowledge beyond the capabilities of current practices. This paper introduces a novel framework for anticipatory LCA that incorporates technology forecasting, risk research, social engagement, and comparative impact assessment, then applies this framework to photovoltaic (PV) technologies. These examples illustrate the potential for anticipatory LCA to prioritize research questions and help guide environmentally responsible innovation of emerging technologies.

  17. Life cycle assessment of offshore and onshore sited wind farms

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-10-15

    This report makes up the final reporting for the project 'Life cycle assessment (LCA) of turbines Analysis of possibilities of product directed environmental optimisation'. The purpose of the project is to carry through a life cycle assessment of an offshore wind farm and an onshore wind farm, respectively, as a basis for assessment of environmental improvement possibilities for wind farms through their life cycles. Likewise, the results are used to elaborate an environmental declaration of contents for power delivered to the grid from both types of wind farms. The project states the environmental impact for electricity produced at Horns Reef offshore wind farm and Tjaereborg onshore wind farm, respectively, as representatives for contemporary Danish offshore wind farms and onshore wind farms, respectively. Tjaereborg onshore wind farm is placed at an utmost favourably location with regard to wind, which means that the production at this wind farm is high compared with other onshore wind farms in Denmark. The high production rate is a factor that is taken into account when assessing the impact on the environment emanating from this wind farm. The results of the environmental life cycle assessments that have been carried out for the two wind farms do not show significant variance. If it is taken into account that Tjaereborg onshore wind farm is placed utmost favourably, the comparison shows that power from an average located onshore wind farm would have a more adverse or corresponding environmental impact as an unfavourably located offshore wind farm. The results show that it is the turbines that causes the largest environmental impact and not to a very high extent the transmission grid. For the turbines, the all-important environmental contribution comes from manufacturing and removal of the turbines, as it is the materials that cause the large environmental strain. The operation of the wind farms gives practically no contribution to the total

  18. Algal biofuels: key issues, sustainability and life cycle assessment

    DEFF Research Database (Denmark)

    Singh, Anoop; Olsen, Stig Irving

    2011-01-01

    In recent years research activities are intensively focused on renewable fuels in order to fulfill the increasing energy demand and to reduce the fossil fuels consumption and external oil dependency either in order to provide local energetic resources and or as a means for reducing greenhouse gases...... (GHG) emissions to reduce the climate change effects. Among the various renewable energy sources algal biofuels is a very promising source of biomass as algae sequester huge quantities of carbon from atmosphere and are very efficient in utilizing the nutrients from the industrial effluent and municipal...... capital investment. The harvested algal biomass and its extracts can be efficiently converted to different biofuels such as bioethanol, biodiesel, biogas and biohydrogen by implementation of various process technologies. Comprehensive life cycle assessments (LCA) of algal biofuels illustrating...

  19. Models for waste life cycle assessment: Review of technical assumptions

    DEFF Research Database (Denmark)

    Gentil, Emmanuel; Damgaard, Anders; Hauschild, Michael Zwicky

    2010-01-01

    , such as the functional unit, system boundaries, waste composition and energy modelling. The modelling assumptions of waste management processes, ranging from collection, transportation, intermediate facilities, recycling, thermal treatment, biological treatment, and landfilling, are obviously critical when comparing......A number of waste life cycle assessment (LCA) models have been gradually developed since the early 1990s, in a number of countries, usually independently from each other. Large discrepancies in results have been observed among different waste LCA models, although it has also been shown that results...... from different LCA studies can be consistent. This paper is an attempt to identify, review and analyse methodologies and technical assumptions used in various parts of selected waste LCA models. Several criteria were identified, which could have significant impacts on the results...

  20. Evaluating the life cycle environmental impact of short span bridges

    DEFF Research Database (Denmark)

    Du, Guangli; Pettersson, Lars; Karoumi, Raid

    2016-01-01

    impact of the construction sector. Life cycle assessment (LCA) is a systematic method for assessing the environmental impact of products and systems, but its application in bridges is scarce. In Swede, most of the bridges are short spans and the type of concrete slab-frame bridge (CFB) accounts...... for a large share. Soil steel composite bridge (SSCB) is a functional equivalent solution for CFB. In order to mitigate the environmental burdens of short span bridges, this paper performed a comparative LCA study between these two types of bridge. The results indicate that the initial material consumption......Bridge infrastructure consumes large amount of energy and raw materials, leading to considerable environmental burdens. The traditional infrastructure construction prioritizes its technical and economic viability. In recent years, the society devotes an ever-increased attention to the environmental...

  1. Evaluating the life cycle environmental impact of short span bridges

    DEFF Research Database (Denmark)

    Du, Guangli; Pettersson, Lars; Karoumi, Raid

    2016-01-01

    Bridge infrastructure consumes large amount of energy and raw materials, leading to considerable environmental burdens. The traditional infrastructure construction prioritizes its technical and economic viability. In recent years, the society devotes an ever-increased attention to the environmental...... impact of the construction sector. Life cycle assessment (LCA) is a systematic method for assessing the environmental impact of products and systems, but its application in bridges is scarce. In Swede, most of the bridges are short spans and the type of concrete slab-frame bridge (CFB) accounts...... for a large share. Soil steel composite bridge (SSCB) is a functional equivalent solution for CFB. In order to mitigate the environmental burdens of short span bridges, this paper performed a comparative LCA study between these two types of bridge. The results indicate that the initial material consumption...

  2. Reputation Life Cycle of The SM Foundation and Customers’ Support

    Directory of Open Access Journals (Sweden)

    Muhammad Alishahdani Ibrahim

    2012-12-01

    Full Text Available Reputation is a key construct in organizational sciences since reputation signals its past behavior and its prospect in the future. The purpose of this paper is to explore the development and influence of both personal and organizational reputation and its impact to customer support. The organiza-tion life cycle theory is applied to the “SM” foundation, one of Indonesian largest Islamic social enterprise which experienced fast growth and decline due to the decline of its leader reputation. The case shows that personal reputation of leader is very important in the start-up and early development phase of the organization but it may threaten the organizational sustainability at a later stage when the leader’s personal reputation is conveyed into the organization reputation.

  3. How life affects the geochemical cycle of carbon

    Science.gov (United States)

    Walker, James C. G.

    1992-01-01

    Developing a quantitative understanding of the biogeochemical cycles of carbon as they have worked throughout Earth history on various time scales, how they have been affected by biological evolution, and how changes in the carbon content of ocean and atmosphere may have affected climate and the evolution of life are the goals of the research. Theoretical simulations were developed that can be tuned to reproduce such data as exist and, once tuned, can be used to predict properties that have not yet been observed. This is an ongoing process, in which models and results are refined as new data and interpretations become available and as understanding of the global system improves. Results of the research are described in several papers which were published or submitted for publication. These papers are summarized. Future research plans are presented.

  4. Life Cycle Assessment of Coal-fired Power Production

    Energy Technology Data Exchange (ETDEWEB)

    Spath, P. L.; Mann, M. K.; Kerr, D. R.

    1999-09-01

    Coal has the largest share of utility power generation in the US, accounting for approximately 56% of all utility-produced electricity (US DOE, 1998). Therefore, understanding the environmental implications of producing electricity from coal is an important component of any plan to reduce total emissions and resource consumption. A life cycle assessment (LCA) on the production of electricity from coal was performed in order to examine the environmental aspects of current and future pulverized coal boiler systems. Three systems were examined: (1) a plant that represents the average emissions and efficiency of currently operating coal-fired power plants in the US (this tells us about the status quo), (2) a new coal-fired power plant that meets the New Source Performance Standards (NSPS), and (3) a highly advanced coal-fired power plant utilizing a low emission boiler system (LEBS).

  5. Defense Waste Processing Facility Process Simulation Package Life Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Reuter, K.

    1991-12-31

    The Defense Waste Processing Facility (DWPF) will be used to immobilize high level liquid radioactive waste into safe, stable, and manageable solid form. The complexity and classification of the facility requires that a performance based operator training to satisfy Department of Energy orders and guidelines. A major portion of the training program will be the application and utilization of Process Simulation Packages to assist in training the Control Room Operators on the fluctionality of the process and the application of the Distribution Control System (DCS) in operating and managing the DWPF process. The packages are being developed by the DWPF Computer and Information Systems Simulation Group. This paper will describe the DWPF Process Simulation Package Life Cycle. The areas of package scope, development, validation, and configuration management will be reviewed and discussed in detail.

  6. Life cycle assessment of biodiesel production from microalgae in ponds.

    Science.gov (United States)

    Campbell, Peter K; Beer, Tom; Batten, David

    2011-01-01

    This paper analyses the potential environmental impacts and economic viability of producing biodiesel from microalgae grown in ponds. A comparative Life Cycle Assessment (LCA) study of a notional production system designed for Australian conditions was conducted to compare biodiesel production from algae (with three different scenarios for carbon dioxide supplementation and two different production rates) with canola and ULS (ultra-low sulfur) diesel. Comparisons of GHG (greenhouse gas) emissions (g CO(2)-e/tkm) and costs (¢/tkm) are given. Algae GHG emissions (-27.6 to 18.2) compare very favourably with canola (35.9) and ULS diesel (81.2). Costs are not so favourable, with algae ranging from 2.2 to 4.8, compared with canola (4.2) and ULS diesel (3.8). This highlights the need for a high production rate to make algal biodiesel economically attractive. Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.

  7. Reliability and life-cycle analysis of deteriorating systems

    CERN Document Server

    Sánchez-Silva, Mauricio

    2016-01-01

    This book compiles and critically discusses modern engineering system degradation models and their impact on engineering decisions. In particular, the authors focus on modeling the uncertain nature of degradation considering both conceptual discussions and formal mathematical formulations. It also describes the basics concepts and the various modeling aspects of life-cycle analysis (LCA).  It highlights the role of degradation in LCA and defines optimum design and operation parameters. Given the relationship between operational decisions and the performance of the system’s condition over time, maintenance models are also discussed. The concepts and models presented have applications in a large variety of engineering fields such as Civil, Environmental, Industrial, Electrical and Mechanical engineering. However, special emphasis is given to problems related to large infrastructure systems. The book is intended to be used both as a reference resource for researchers and practitioners and as an academic text ...

  8. Life cycle assessment in support of sustainable transportation

    Science.gov (United States)

    Eckelman, Matthew J.

    2013-06-01

    In our rapidly urbanizing world, sustainable transportation presents a major challenge. Transportation decisions have considerable direct impacts on urban society, both positive and negative, for example through changes in transit times and economic productivity, urban connectivity, tailpipe emissions and attendant air quality concerns, traffic accidents, and noise pollution. Much research has been dedicated to quantifying these direct impacts for various transportation modes. Transportation planning decisions also result in a variety of indirect environmental and human health impacts, a portion of which can accrue outside of the transit service area and so outside of the local decision-making process. Integrated modeling of direct and indirect impacts over the life cycle of different transportation modes provides decision support that is more comprehensive and less prone to triggering unintended consequences than a sole focus on direct tailpipe emissions. The recent work of Chester et al (2013) in this journal makes important contributions to this research by examining the environmental implications of introducing bus rapid transit and light rail in Los Angeles using life cycle assessment (LCA). Transport in the LA region is dominated by automobile trips, and the authors show that potential shifts to either bus or train modes would reduce energy use and emissions of criteria air pollutants, on an average passenger mile travelled basis. This work compares not just the use of each vehicle, but also upstream impacts from its manufacturing and maintenance, as well as the construction and maintenance of the entire infrastructure required for each mode. Previous work by the lead author (Chester and Horvath 2009), has shown that these non-operational sources and largely non-local can dominate life cycle impacts from transportation, again on an average (or attributional) basis, for example increasing rail-related GHG emissions by >150% over just operational emissions

  9. Environmental Performance of Kettle Production: Product Life Cycle Assessment

    Science.gov (United States)

    Marcinkowski, Andrzej; Zych, Krzysztof

    2017-12-01

    The main objective of this paper is to compare the environmental impact caused by two different types of water boiling processes. The aim was achieved thanks to product life cycle assessment (LCA) conducted for stovetop and electric kettles. A literature review was carried out. A research model was worked out on the basis of data available in literature as well as additional experiments. In order to have a better opportunity to compare LCA results with reviewed literature, eco-indicator 99 assessment method was chosen. The functional unit included production, usage and waste disposal of each product (according to from cradle to grave approach) where the main function is boiling 3360 l of water during 4-year period of time. A very detailed life cycle inventory was carried out. The mass of components was determined with accuracy of three decimal places (0.001 g). The majority of environmental impact is caused by electricity or natural gas consumption during usage stage: 92% in case of the electric and kettle and 99% in case of stovetop one. Assembly stage contributed in 7% and 0.8% respectively. Uncertainty and sensitivity analyses took into consideration various waste scenario patterns as well as demand for transport. Environmental impact turned out to be strongly sensitive to a chosen pattern of energy delivery (electricity mix) which determined final comparison results. Basing on LCA results, some improvements of products were suggested. The boiling time optimization was pointed out for electric kettle's efficiency improvement. Obtained results can be used by manufacturers in order to improve their eco-effectiveness. Moreover, conclusions following the research part can influence the future choices of home appliances users.

  10. The life-cycle of Riemann-Silberstein electromagnetic vortices

    Science.gov (United States)

    Nye, J. F.

    2017-11-01

    To study the singularities of a monochromatic electromagnetic wave field in free space, it is desirable to use a quantity that combines both the electric field E and the magnetic field B in equal measure. The Riemann-Silberstein (R-S) field is a way of doing this. It is based on the real physical E and B and one constructs from them the complex vector field {F}={E}+{{i}} {B}. Then, one constructs {F}\\cdot {F} and studies the optical vortices of this R-S complex scalar field. Unlike the better-known and much studied optical vortices of a monochromatic complex scalar field, which are stationary, these vortices are normally in continual motion; they oscillate at the optical frequency. We study their life cycle in the simplest model that is sufficiently generic, namely, fields generated by the interference of four randomly chosen plane elliptically polarised waves. The topological events in the life cycle do not repeat on a 3D space lattice in a stationary laboratory frame. In space-time, however, the R-S vortices are invariant under any Lorentz transformation, and because of this and the inherent time repetition there is a particular moving frame in space-time, reached by a Lorentz transformation, where there exists a repeating pattern of events in space. Its 4D unit cell constitutes, in effect, a description of the whole infinite pattern. Just because they are in constant motion, it is not surprising that the R-S vortex lines in the model make reconnections and appear as rings that either shrink to nothing or appear from nothing. However, these processes occur in groups of four, reflecting the fact that the unit cell is face-centred. What distinguishes the R-S field from the other complex scalar fields containing vortices is the existence of this face-centred repeating cell.

  11. Life cycle primary energy analysis of residential buildings

    Energy Technology Data Exchange (ETDEWEB)

    Gustavsson, Leif; Joelsson, Anna [Ecotechnology, Department of Engineering and Sustainable Development, Mid Sweden University, SE-831 25 Oestersund (Sweden)

    2010-02-15

    The space heating demand of residential buildings can be decreased by improved insulation, reduced air leakage and by heat recovery from ventilation air. However, these measures result in an increased use of materials. As the energy for building operation decreases, the relative importance of the energy used in the production phase increases and influences optimization aimed at minimizing the life cycle energy use. The life cycle primary energy use of buildings also depends on the energy supply systems. In this work we analyse primary energy use and CO{sub 2} emission for the production and operation of conventional and low-energy residential buildings. Different types of energy supply systems are included in the analysis. We show that for a conventional and a low-energy building the primary energy use for production can be up to 45% and 60%, respectively, of the total, depending on the energy supply system, and with larger variations for conventional buildings. The primary energy used and the CO{sub 2} emission resulting from production are lower for wood-framed constructions than for concrete-framed constructions. The primary energy use and the CO{sub 2} emission depend strongly on the energy supply, for both conventional and low-energy buildings. For example, a single-family house from the 1970s heated with biomass-based district heating with cogeneration has 70% lower operational primary energy use than if heated with fuel-based electricity. The specific primary energy use with district heating was 40% lower than that of an electrically heated passive row house. (author)

  12. Application of life cycle analysis: The case of green bullets

    Energy Technology Data Exchange (ETDEWEB)

    Bogard, J.S.; Yuracko, K.L.; Murray, M.E.; Lowden, R.A.; Vaughn, N.L.

    1998-06-01

    Life-cycle analysis (LCA) has been used to analyze the desirability of replacing lead with a composite of tungsten and tin in projectile slugs used in small arms ammunition at US Department of Energy (DOE) training facilities for security personnel. The analysis includes consideration of costs, performance, environmental and human health impacts, availability of raw materials, and stakeholder acceptance. The DOE expends approximately 10 million rounds of small-arms ammunition each year training security personnel. This deposits over 300,000 pounds of lead and copper annually into DOE firing ranges, contributing to lead migration in the surrounding environment. Human lead intake occurs by inhalation of contaminated indoor firing range air and air containing lead particles that are resuspended during regular maintenance and cleanup, and by skin absorption while cleaning weapons. Projectiles developed by researchers at Oak Ridge National Laboratory (ORNL) using a composite of tungsten and tin perform as well as, or better than, those fabricated using lead. A cost analysis shows that tungsten-tin is less costly to use than lead, since, for the current number of rounds used annually, the higher tungsten-tin purchase price is small compared with higher maintenance costs associated with lead. The tungsten-tin composite presents a much smaller potential for adverse human health and environmental impacts than lead. Only a small fraction of the world`s tungsten production occurs in the United States, however, and market-economy countries account for only around 15% of world tungsten production. Life cycle analysis clearly shows that advantages outweigh risks in replacing lead with tungsten-tin in small-caliber projectiles at DOE training facilities. Concerns about the availability of raw tungsten are mitigated by the ease of converting back to lead (if necessary) and the recyclability of tungsten-tin rounds.

  13. Deployable bamboo structure project: A building life-cycle report

    Science.gov (United States)

    Firdaus, Adrian; Prastyatama, Budianastas; Sagara, Altho; Wirabuana, Revian N.

    2017-11-01

    Bamboo is considered as a sustainable material in the world of construction, and it is vastly available in Indonesia. The general utilization of the material is increasingly frequent, however, its usage as a deployable structure-a recently-developed use of bamboo, is still untapped. This paper presents a report on a deployable bamboo structure project, covering the entire building life-cycle phase. The cycle encompasses the designing; fabrication; transportation; construction; operation and maintenance; as well as a plan for future re-use. The building is made of a configuration of the structural module, each being a folding set of bars which could be reduced in size to fit into vehicles for easy transportation. Each structural module was made of Gigantochloa apus bamboo. The fabrication, transportation, and construction phase require by a minimum of three workers. The fabrication and construction phase require three hours and fifteen minutes respectively. The building is utilized as cafeteria stands, the operation and maintenance phase started since early March 2017. The maintenance plan is scheduled on a monthly basis, focusing on the inspection of the locking mechanism element and the entire structural integrity. The building is designed to allow disassembly process so that it is reusable in the future.

  14. Diel cycling and long-term persistence of viruses in the ocean’s euphotic zone

    Science.gov (United States)

    Aylward, Frank O.; Boeuf, Dominique; Mende, Daniel R.; Wood-Charlson, Elisha M.; Vislova, Alice; Eppley, John M.; Romano, Anna E.

    2017-01-01

    Viruses are fundamental components of marine microbial communities that significantly influence oceanic productivity, biogeochemistry, and ecosystem processes. Despite their importance, the temporal activities and dynamics of viral assemblages in natural settings remain largely unexplored. Here we report the transcriptional activities and variability of dominant dsDNA viruses in the open ocean’s euphotic zone over daily and seasonal timescales. While dsDNA viruses exhibited some fluctuation in abundance in both cellular and viral size fractions, the viral assemblage was remarkably stable, with the most abundant viral types persisting over many days. More extended time series indicated that long-term persistence (>1 y) was the rule for most dsDNA viruses observed, suggesting that both core viral genomes as well as viral community structure were conserved over interannual periods. Viral gene transcription in host cell assemblages revealed diel cycling among many different viral types. Most notably, an afternoon peak in cyanophage transcriptional activity coincided with a peak in Prochlorococcus DNA replication, indicating coordinated diurnal coupling of virus and host reproduction. In aggregate, our analyses suggested a tightly synchronized diel coupling of viral and cellular replication cycles in both photoautotrophic and heterotrophic bacterial hosts. A surprising consequence of these findings is that diel cycles in the ocean’s photic zone appear to be universal organizing principles that shape ecosystem dynamics, ecological interactions, and biogeochemical cycling of both cellular and acellular community components. PMID:29073070

  15. Diel cycling and long-term persistence of viruses in the ocean's euphotic zone.

    Science.gov (United States)

    Aylward, Frank O; Boeuf, Dominique; Mende, Daniel R; Wood-Charlson, Elisha M; Vislova, Alice; Eppley, John M; Romano, Anna E; DeLong, Edward F

    2017-10-24

    Viruses are fundamental components of marine microbial communities that significantly influence oceanic productivity, biogeochemistry, and ecosystem processes. Despite their importance, the temporal activities and dynamics of viral assemblages in natural settings remain largely unexplored. Here we report the transcriptional activities and variability of dominant dsDNA viruses in the open ocean's euphotic zone over daily and seasonal timescales. While dsDNA viruses exhibited some fluctuation in abundance in both cellular and viral size fractions, the viral assemblage was remarkably stable, with the most abundant viral types persisting over many days. More extended time series indicated that long-term persistence (>1 y) was the rule for most dsDNA viruses observed, suggesting that both core viral genomes as well as viral community structure were conserved over interannual periods. Viral gene transcription in host cell assemblages revealed diel cycling among many different viral types. Most notably, an afternoon peak in cyanophage transcriptional activity coincided with a peak in Prochlorococcus DNA replication, indicating coordinated diurnal coupling of virus and host reproduction. In aggregate, our analyses suggested a tightly synchronized diel coupling of viral and cellular replication cycles in both photoautotrophic and heterotrophic bacterial hosts. A surprising consequence of these findings is that diel cycles in the ocean's photic zone appear to be universal organizing principles that shape ecosystem dynamics, ecological interactions, and biogeochemical cycling of both cellular and acellular community components. Copyright © 2017 the Author(s). Published by PNAS.

  16. The evolution of life cycle complexity in aphids: Ecological optimization or historical constraint?

    Science.gov (United States)

    Hardy, Nate B; Peterson, Daniel A; von Dohlen, Carol D

    2015-06-01

    For decades, biologists have debated why many parasites have obligate multihost life cycles. Here, we use comparative phylogenetic analyses of aphids to evaluate the roles of ecological optimization and historical constraint in the evolution of life cycle complexity. If life cycle complexity is adaptive, it should be evolutionarily labile, that is, change in response to selection. We provide evidence that this is true in some aphids (aphidines), but not others (nonaphidines)-groups that differ in the intensity of their relationships with primary hosts. Next, we test specific mechanisms by which life cycle complexity could be adaptive or a constraint. We find that among aphidines there is a strong association between complex life cycles and polyphagy but only a weak correlation between life cycle complexity and reproductive mode. In contrast, among nonaphidines the relationship between life cycle complexity and host breadth is weak but the association between complex life cycles and sexual reproduction is strong. Thus, although the adaptiveness of life cycle complexity appears to be lineage specific, across aphids, life cycle evolution appears to be tightly linked with the evolution of other important natural history traits. © 2015 The Author(s). Evolution © 2015 The Society for the Study of Evolution.

  17. Application of Life Cycle Assessment on Electronic Waste Management: A Review.

    Science.gov (United States)

    Xue, Mianqiang; Xu, Zhenming

    2017-04-01

    Electronic waste is a rich source of both valuable materials and toxic substances. Management of electronic waste is one of the biggest challenges of current worldwide concern. As an effective and prevailing environmental management tool, life cycle assessment can evaluate the environmental performance of electronic waste management activities. Quite a few scientific literatures reporting life cycle assessment of electronic waste management with significant outcomes have been recently published. This paper reviewed the trends, characteristics, research gaps, and challenges of these studies providing detailed information for practitioners involved in electronic waste management. The results showed that life cycle assessment studies were most carried out in Europe, followed by Asia and North America. The research subject of the studies mainly includes monitors, waste printed circuit boards, mobile phones, computers, printers, batteries, toys, dishwashers, and light-emitting diodes. CML was the most widely used life cycle impact assessment method in life cycle assessment studies on electronic waste management, followed by EI99. Furthermore, 40% of the reviewed studies combined with other environmental tools, including life cycle cost, material flow analysis, multi-criteria decision analysis, emergy analysis, and hazard assessment which came to more comprehensive conclusions from different aspects. The research gaps and challenges including uneven distribution of life cycle assessment studies, life cycle impact assessment methods selection, comparison of the results, and uncertainty of the life cycle assessment studies were examined. Although life cycle assessment of electronic waste management facing challenges, their results will play more and more important role in electronic waste management practices.

  18. Application of Life Cycle Assessment on Electronic Waste Management: A Review

    Science.gov (United States)

    Xue, Mianqiang; Xu, Zhenming

    2017-04-01

    Electronic waste is a rich source of both valuable materials and toxic substances. Management of electronic waste is one of the biggest challenges of current worldwide concern. As an effective and prevailing environmental management tool, life cycle assessment can evaluate the environmental performance of electronic waste management activities. Quite a few scientific literatures reporting life cycle assessment of electronic waste management with significant outcomes have been recently published. This paper reviewed the trends, characteristics, research gaps, and challenges of these studies providing detailed information for practitioners involved in electronic waste management. The results showed that life cycle assessment studies were most carried out in Europe, followed by Asia and North America. The research subject of the studies mainly includes monitors, waste printed circuit boards, mobile phones, computers, printers, batteries, toys, dishwashers, and light-emitting diodes. CML was the most widely used life cycle impact assessment method in life cycle assessment studies on electronic waste management, followed by EI99. Furthermore, 40% of the reviewed studies combined with other environmental tools, including life cycle cost, material flow analysis, multi-criteria decision analysis, emergy analysis, and hazard assessment which came to more comprehensive conclusions from different aspects. The research gaps and challenges including uneven distribution of life cycle assessment studies, life cycle impact assessment methods selection, comparison of the results, and uncertainty of the life cycle assessment studies were examined. Although life cycle assessment of electronic waste management facing challenges, their results will play more and more important role in electronic waste management practices.

  19. Petri Net Modeling of Computer Virus Life Cycle | Ikekonwu ...

    African Journals Online (AJOL)

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  20. PROJECT LIFE CYCLE OF LEASING MARINE VESSEL OWNERS AND CHARTERERS

    Directory of Open Access Journals (Sweden)

    Алла Витальевна БОНДАРЬ

    2016-03-01

    Full Text Available Based on the study of the basic types of the bareboat charter, presented algorithms decision on the justification of the respective projects. It was found that the initiator of the project can be both owners who wants to pass the boat rental and the charterer, and also who is the owner, who wants to take a boat for rent. It is proved that the implementation of these specific operations requires careful preparation, and using of the project approach will greatly enhance their effectiveness. We describe the life of the project finance lease from the standpoint of the marine vessel, the ship-owner and charterer. It is established that such projects characterized by four-phase structure of the life cycle: preparation, let's call it as the principal decision on (from the chartering of the vessel, the investment - to select the optimal variant (from the charter and the conclusion of the bareboat charter, the phase of operation of the vessel and the fourth - the closure of the project at the end of term bareboat charter. Skill description of the content of each phase, which will continue for the main participants of the project to determine the value of each phase and the value of the whole project.

  1. Life cycle cost analysis of aging aircraft airframe maintenance

    Science.gov (United States)

    Sperry, Kenneth Robert

    Scope and method of study. The purpose of this study was to examine the relationship between an aircraft's age and its annual airframe maintenance costs. Common life cycle costing methodology has previously not recognized the existence of this cost growth potential, and has therefor not determined the magnitude nor significance of this cost element. This study analyzed twenty-five years of DOT Form 41-airframe maintenance cost data for the Boeing 727, 737, 747 and McDonnell Douglas DC9 and DC-10 aircraft. Statistical analysis included regression analysis, Pearson's r, and t-tests to test the null hypothesis. Findings and conclusion. Airframe maintenance cost growth was confirmed to be increasing after an aircraft's age exceeded its designed service objective of approximately twenty-years. Annual airframe maintenance cost growth increases were measured ranging from 3.5% annually for a DC-9, to approximately 9% annually for a DC-10 aircraft. Average measured coefficient of determination between age and airframe maintenance, exceeded .80, confirming a strong relationship between cost: and age. The statistical significance of the difference between airframe costs sampled in 1985, compared to airframe costs sampled in 1998 was confirmed by t-tests performed on each subject aircraft group. Future cost forecasts involving aging aircraft subjects must address cost growth due to aging when attempting to model an aircraft's economic service life.

  2. The life cycle dimension of time transfers in Europe

    Directory of Open Access Journals (Sweden)

    Marina Zannella

    2013-11-01

    Full Text Available Background: Reallocation of economic resources between generations and genders has important consequences for economic growth and inequality. Unpaid work is a relevant component of intergenerational transfers, but is invisible to traditional accounts. Time use data can complement accounts of monetary transfers. Objective: The main goal of this article is to provide estimates of life cycle profiles of consumption and production of unpaid activities. These profiles can be used to evaluate transfers of time by age and sex. Methods: We use data from the Multinational Time Use Study (MTUS to estimate profiles of time allocated to unpaid productive activities, by age, sex and household structure, for selected European countries. The unpaid working time is then distributed, with a statistical model, to those age groups that benefit from it, in order to estimate age-specific consumption profiles of time. Results: We observe large transfers of time from females to males, and from adults to children. Life course trajectories are qualitatively similar across countries, but with significant variations in levels. Differences in profiles by household structure may be associated with incentives or disincentives for particular fertility choices in different social and institutional settings. Conclusions: This article quantifies household production and non-market transfers. It offers insight into the underestimation of the economic contribution of women. Comments: This article provides some descriptive findings that could be incorporated with other research pursued by scholars in the National Transfer Accounts (NTA project to monetize the value of time and include it in standard transfer accounts.

  3. Entry into the Postparental Phase of the Family Life Cycle

    Directory of Open Access Journals (Sweden)

    Barbara Wawrzyniak

    2015-02-01

    Full Text Available Der Originalbeitrag in deutscher Sprache ist verfügbar unter: Bd. 40 (2015: Ausgewählte deutsche BeiträgeThe article examines entry into the postparental phase of the family life cycle, which is the familial situation when all children have moved out of the parental household. We position this event chronologically within the life course and examine the probability of occurrence. Using panel data (3 survey waves covering a period of 40 years of a cohort of former North-Rhine Westphalian grammar school pupils, event history models (Cox regression are employed to analyse what factors accelerate or decelerate the transition. This revealed that the parent’s individual biography (in particular the age at the own move out, age at the birth of the first child and the number of children has a major impact on the time of occurrence, while the occupational history has no effect. In addition, sons delay the transition, while children’s academic studies and occupation accelerate it.

  4. Life cycle assessment of automobile/fuel options.

    Science.gov (United States)

    MacLean, Heather L; Lave, Lester B

    2003-12-01

    We examine the possibilities for a "greener" car that would use less material and fuel, be less polluting, and would have a well-managed end-of-life. Light-duty vehicles are fundamental to our economy and will continue to be for the indefinite future. Any redesign to make these vehicles greener requires consumer acceptance. Consumer desires for large, powerful vehicles have been the major stumbling block in achieving a "green car". The other major barrier is inherent contradictions among social goals such as fuel economy, safety, low emissions of pollutants, and low emissions of greenhouse gases, which has led to conflicting regulations such as emissions regulations blocking sales of direct injection diesels in California, which would save fuel. In evaluating fuel/vehicle options with the potential to improve the greenness of cars [diesel (direct injection) and ethanol in internal combustion engines, battery-powered, gasoline hybrid electric, and hydrogen fuel cells], we find no option dominates the others on all dimensions. The principles of green design developed by Anastas and Zimmerman (Environ. Sci. Technol. 2003, 37, 94A-101A) and the use of a life cycle approach provide insights on the key sustainability issues associated with the various options.

  5. Life cycle replacement by gene introduction under an allee effect in periodical cicadas.

    Directory of Open Access Journals (Sweden)

    Yukiko Nariai

    Full Text Available Periodical cicadas (Magicicada spp. in the USA are divided into three species groups (-decim, -cassini, -decula of similar but distinct morphology and behavior. Each group contains at least one species with a 17-year life cycle and one with a 13-year cycle; each species is most closely related to one with the other cycle. One explanation for the apparent polyphyly of 13- and 17-year life cycles is that populations switch between the two cycles. Using a numerical model, we test the general feasibility of life cycle switching by the introduction of alleles for one cycle into populations of the other cycle. Our results suggest that fitness reductions at low population densities of mating individuals (the Allee effect could play a role in life cycle switching. In our model, if the 13-year cycle is genetically dominant, a 17-year cycle population will switch to a 13-year cycle given the introduction of a few 13-year cycle alleles under a moderate Allee effect. We also show that under a weak Allee effect, different year-classes ("broods" with 17-year life cycles can be generated. Remarkably, the outcomes of our models depend only on the dominance relationships of the cycle alleles, irrespective of any fitness advantages.

  6. Life cycle and nano-products: end-of-life assessment

    Science.gov (United States)

    Asmatulu, Eylem; Twomey, Janet; Overcash, Michael

    2012-03-01

    Understanding environmental impacts of nanomaterials necessitates analyzing the life cycle profile. The initial emphasis of nanomaterial life cycle studies has been on the environmental and health effects of nanoproducts during the production and usage stages. Analyzing the end-of-life (eol) stage of nanomaterials is also critical because significant impacts or benefits for the environment may arise at that particular stage. In this article, the Woodrow Wilson Center's Project on Emerging Nanotechnologies (PEN) Consumer Products Inventory (CPI) model was used, which contains a relatively large and complete nanoproduct list (1,014) as of 2010. The consumer products have wide range of applications, such as clothing, sports goods, personal care products, medicine, as well as contributing to faster cars and planes, more powerful computers and satellites, better micro and nanochips, and long-lasting batteries. In order to understand the eol cycle concept, we allocated 1,014 nanoproducts into the nine end-of-life categories (e.g., recyclability, ingestion, absorption by skin/public sewer, public sewer, burning/landfill, landfill, air release, air release/public sewer, and other) based on probable final destinations of the nanoproducts. This article highlights the results of this preliminary assessment of end-of-life stage of nanoproducts. The largest potential eol fate was found to be recyclability, however little literature appears to have evolved around nanoproduct recycling. At lower frequency is dermal and ingestion human uptake and then landfill. Release to water and air are much lower potential eol fates for current nanoproducts. In addition, an analysis of nano-product categories with the largest number of products listed indicated that clothes, followed by dermal-related products and then sports equipment were the most represented in the PEN CPI (http://www.nanotechproject.org/inventories/consumer/browse/categories/, 2010).

  7. Minimising life cycle costs of automated valves in offshore platforms

    Energy Technology Data Exchange (ETDEWEB)

    Yli-Petays, Juha [Metso Automation do Brasil Ltda., Rio de Janeiro, RJ (Brazil); Niemela, Ismo [Metso Automation, Imatra (Finland)

    2012-07-01

    Automated process valves play an essential role in offshore platforms operation. If you are able to optimize their operation and maintenance activities you can receive extensive operational savings with minimal investment. Valves used in offshore platforms doesn't differentiate that much from the valves used in downstream but there are certain specialties, which makes the operations more challenging in offshore: Process valves are more difficult to access and maintain because of space limitations. Also spare part inventories and deliveries are challenging because of offshore platform's remote location. To overcome these challenges usage of digital positioners with diagnostic features has become more common because predictive maintenance capabilities enable possibilities to plan the maintenance activities and this way optimise the spare part orders regarding to valves. There are intelligent controllers available for control valves, automated on/off valves as well as ESD-valves and whole network of automated valves on platforms can be controlled by intelligent valve controllers. This creates many new opportunities in regards of optimized process performance or predictive maintenance point-of-view. By means of intelligent valve controllers and predictive diagnostics, condition monitoring and maintenance planning can also be performed remotely from an onshore location. Thus, intelligent valve controllers provide good way to minimize spending related to total cost of ownership of automated process valves. When purchase value of control valve represent 20% of TCO, intelligent positioner and predictive maintenance methods can enable as high as 30% savings over the life cycle of asset so basically it benefit savings higher than whole investment of monitored asset over its life cycle. This is mainly achieved through the optimized maintenance activities since real life examples has shown that with time based maintenance (preventive maintenance) approach 70% of

  8. Life Cycle Cost optimization of a BOLIG+ Zero Energy Building

    Energy Technology Data Exchange (ETDEWEB)

    Marszal, A.J.

    2011-12-15

    Buildings consume approximately 40% of the world's primary energy use. Considering the total energy consumption throughout the whole life cycle of a building, the energy performance and supply is an important issue in the context of climate change, scarcity of energy resources and reduction of global energy consumption. An energy consuming as well as producing building, labelled as the Zero Energy Building (ZEB) concept, is seen as one of the solutions that could change the picture of energy consumption in the building sector, and thus contribute to the reduction of the global energy use. However, before being fully implemented in the national building codes and international standards, the ZEB concept requires a clear understanding and a uniform definition. The ZEB concept is an energy-conservation solution, whose successful adaptation in real life depends significantly on private building owners' approach to it. For this particular target group, the cost is often an obstacle when investing money in environmental or climate friendly products. Therefore, this PhD project took the perspective of a future private ZEB owner to investigate the cost-optimal Net ZEB definition applicable in the Danish context. The review of the various ZEB approaches indicated a general concept of a Zero Energy Building as a building with significantly reduced energy demand that is balanced by an equivalent energy generation from renewable sources. And, with this as a general framework, each ZEB definition should further specify: (1) the connection or the lack of it to the energy infrastructure, (2) the unit of the balance, (3) the period of the balance, (4) the types of energy use included in the balance, (5) the minimum energy performance requirements (6) the renewable energy supply options, and if applicable (7) the requirements of the building-grid interaction. Moreover, the study revealed that the future ZEB definitions applied in Denmark should mostly be focused on grid

  9. The Life Cycle of Images: Revisiting the Ethical Treatment of the Art Therapy Image

    Science.gov (United States)

    Hinz, Lisa D.

    2013-01-01

    Using the metaphor of the human life cycle, the author of this viewpoint suggests that consideration of the birth, life, and death of images made in art therapy may promote a new perspective on their ethical treatment. A developmental view of images encourages art therapists to see art images as living entities that undergo a natural life cycle.…

  10. Frameworks and technologies for exchanging and sharing product life cycle knowledge

    NARCIS (Netherlands)

    Gerritsen, B.; Gielingh, W.; Dankwort, W.; Anderl, R.

    2011-01-01

    Frameworks and technologies for exchanging and sharing product life cycle knowledge (PLK) are discussed. A life cycle-centric knowledge management approach with stakeholders-in-the-loop allows for a life-long evaluation of the instantaneous performance and the consequential decision making about the

  11. Complete canine papillomavirus life cycle in pigmented lesions.

    Science.gov (United States)

    Lange, Christian E; Tobler, Kurt; Schraner, Elisabeth M; Vetsch, Elisabeth; Fischer, Nina M; Ackermann, Mathias; Favrot, Claude

    2013-03-23

    Canine papillomaviruses (CPVs) have been identified in various benign and malignant neoplastic skin disorders. The most frequent manifestations of CPV infections are classical warts and pigmented plaques. Although the etiology of canine oral papillomatosis is well established, knowledge about CPVs role in the development of pigmented plaques remains vague. Indeed, as CPV DNA may frequently be found on clinically healthy canine skin, its mere detection in lesions cannot be regarded as a sufficient indicator of causality. Whether CPVs are actually active in pigmented plaques, a requirement for any conceivable involvement, is consequently an open question. To inquire such viral activity, two distinct clinical cases of canine pigmented lesions were evaluated in greater detail. The histological findings in the two cases supported the clinical diagnosis of pigmented viral plaques. Sequencing of amplified DNA from these lesions revealed the genomes of two novel CPV types, i.e. CPV9 and CPV14, both putatively belonging to the genus Chi. Furthermore, transcription and splicing of corresponding CPV mRNA could be shown by RT-PCR in the respective lesions. Finally, viral particles were detected by electron microscopy in homogenates as well as in nuclei of keratinocytes in pigmented lesions. In conclusion, the results link clinical signs of pigmented plaques to histological changes, the presence of CPV specific DNA, viral gene transcription, and the presence of viral particles in and from the lesions. Thus, the findings outline the entire replicative cycle of CPVs in pigmented plaques, which might help understanding the relationship between these viruses and the associated disorders. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Plant Growth and Development: An Outline for a Unit Structured Around the Life Cycle of Rapid-Cycling Brassica Rapa.

    Science.gov (United States)

    Becker, Wayne M.

    This outline is intended for use in a unit of 10-12 lectures on plant growth and development at the introductory undergraduate level as part of a course on organismal biology. The series of lecture outlines is structured around the life cycle of rapid-cycling Brassica rapa (RCBr). The unit begins with three introductory lectures on general plant…

  13. The Behavioral Life-Cycle Theory Of Consumer Behavior: Survey Evidence

    OpenAIRE

    Fred Graham; Alan G. Isaac

    2000-01-01

    We find that survey evidence on faculty pay-cycle choice strongly contradicts the neoclassical theory of consumer behavior. It is more favorable to the behavioral life-cycle theory of Shefrin and Thaler (1988).

  14. Dissecting the role of viruses in marine nutrient cycling

    DEFF Research Database (Denmark)

    Shelford, Emma J.; Jørgensen, Niels O. G.; Rasmussen, Susan

    2014-01-01

    Lysis of marine bacteria by viruses releases a range of organic compounds into the environment, including D- and L-amino acids, but the uptake of these compounds by other bacteria is not well characterized. This study determined that Photobacterium sp. strain SKA34 (Gamma - proteobacteria......) increased in abundance following uptake of D- and L-amino acids from viral lysate of Cellulophaga sp. strain MM#3 (Flavobacteria). Ammonium and dissolved free amino acids were taken up almost to detection limits, suggesting that the C:N ratio of bioavailable organic matter in the lysate was high...

  15. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a t echnoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  16. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a technoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  17. The importance of life cycle concepts for the development of safe nanoproducts

    DEFF Research Database (Denmark)

    Som, Claudia; Berges, Markus; Chaudhry, Qasim

    2010-01-01

    concept – may be used to assess the relative environmental sustainability performance of nanoproducts in comparison with their conventional equivalents. Other less formalized life cycle concepts in the framework of prospective technology assessment may uncover further detailed and prospective knowledge...... will require the generation of new basic knowledge, it is unlikely that they will be resolved in the immediate future. One has to consider the whole life cycle of nanoproducts to ensure that possible impacts can be systematically discovered. For example, life cycle assessment (LCA) – a formalized life cycle...... for human and environmental exposure to ENMs during the life cycle of nanoproducts. They systematically reveal impacts such as cross product contamination or dissipation of scarce materials among others. The combination of different life cycle concepts with the evolving knowledge from toxicology and risk...

  18. A Framework for BIM-Enabled Life-Cycle Information Management of Construction Project

    Directory of Open Access Journals (Sweden)

    Xun Xu

    2014-08-01

    Full Text Available BIM has been widely used in project management, but on the whole the applications have been scattered and the BIM models have not been deployed throughout the whole project life-cycle. Each participant builds their own BIM, so there is a major problem in how to integrate these dynamic and fragmented data together. In order to solve this problem, this paper focuses on BIM-based life-cycle information management and builds a framework for BIM-enabled life-cycle information management. To organize the life-cycle information well, the information components and information flow during the project life-cycle are defined. Then, the application of BIM in life-cycle information management is analysed. This framework will provide a unified platform for information management and ensure data integrity.

  19. The circle of life: A cross-cultural comparison of children's attribution of life-cycle traits.

    Science.gov (United States)

    Burdett, Emily R R; Barrett, Justin L

    2016-06-01

    Do children attribute mortality and other life-cycle traits to all minded beings? The present study examined whether culture influences young children's ability to conceptualize and differentiate human beings from supernatural beings (such as God) in terms of life-cycle traits. Three-to-5-year-old Israeli and British children were questioned whether their mother, a friend, and God would be subject to various life-cycle processes: Birth, death, ageing, existence/longevity, and parentage. Children did not anthropomorphize but differentiated among human and supernatural beings, attributing life-cycle traits to humans, but not to God. Although 3-year-olds differentiated significantly among agents, 5-year-olds attributed correct life-cycle traits more consistently than younger children. The results also indicated some cross-cultural variation in these attributions. Implications for biological conceptual development are discussed. © 2015 The British Psychological Society.

  20. Research on Business Models in their Life Cycle

    Directory of Open Access Journals (Sweden)

    Adam Jabłoński

    2016-04-01

    Full Text Available The paper presents the results of theoretical discussions and research findings in the field of designing sustainable business models that support the creation of value at various stages of the business life cycle. The paper presents selected findings of extensive research into the business models of Polish companies listed on the Warsaw Stock Exchange. Companies which are at various stages of development should build and adapt their business models in order to maintain the ability to create value for stakeholders. Characteristics of business models at the early stages of development are different than at mature stages. The paper highlights the differences in business models in the context of the life cycle of companies and sustainability criteria. The paper presents research findings which show that the company’s development can be seen from the point of view of the business model. Research on business models concentrated on identifying the key attributes and the configuration of the business models appropriate for the early stage of development as well as the maturity stage. It was found that the business models of companies at an early stage of the development of companies listed on the Warsaw Stock Exchange are oriented primarily to how the company shapes, delivers, and captures value from the market in order to generate profits for shareholders and increase the value of the company, while the business models of mature companies include the intentions of management used to balance objectives with respect to different groups of stakeholders, and to carefully formulate and implement business objectives with particular attention paid to preserving the sustainability of the business. The assessment of business models from the point of view of the life cycle proves that managers change their approach to configuring business models over time; at some point, they include management intentions aimed at a broader range of goals than merely