Sample records for vingrinjumu krjums ar

  1. Ars Electronica

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten


    Anmeldelse af Ars Electronica festivalen 3. - 8. september, 2009 i Linz, Østrig, der fejrede 30 års jubilæum under temaet "Human Nature". Festivalen fokuserer på interaktion mellem menneske, teknologi, kunst og samfund med særlig vægt på udviklingen af computeren og det digitale. Udgivelsesdato: 15.12...

  2. ScattAR

    DEFF Research Database (Denmark)

    Baldwin, Alex Dempster; Serafin, Stefania; Erkut, Cumhur


    We present an augmented reality (AR) audio application where scattering delay networks efficiently generate and organize a reverberator, based on room geometry scanned by an AR device. The application allows for real-time processing and updating of reflection path geometry. It provides a proof...

  3. Ars Himera / Irina Lobanova

    Index Scriptorium Estoniae

    Lobanova, Irina


    Iseloomustatakse praegust aega ja moodsat kunsti: valitseb vastutustundetus ja ebainimlikkus. Näited - professor von Hageni "Korpwelten" ja uusim kunstinähtus Ars Chimaera - eksponeerimise eesmärgil surrogaatsete elusolendite saamise kunst

  4. ScattAR

    DEFF Research Database (Denmark)

    Baldwin, Alex Dempster; Serafin, Stefania; Erkut, Cumhur


    We present an augmented reality (AR) audio application where scattering delay networks efficiently generate and organize a reverberator, based on room geometry scanned by an AR device. The application allows for real-time processing and updating of reflection path geometry. It provides a proof-of......-of-concept for plausible audio-visual registration of a virtual object in a real environment, but further tests are needed in perceptual evaluation....

  5. Superdeformation of Ar hypernuclei (United States)

    Isaka, Masahiro; Kimura, Masaaki; Hiyama, Emiko; Sagawa, Hiroyuki


    We investigate the differences in the Λ separation energies (S_Λ ) of the ground and superdeformed (SD) states in {}^{37}_Λ Ar, ^{39}_Λ Ar, and ^{41}_Λ Ar within the framework of antisymmetrized molecular dynamics (AMD). In this study, we find that the calculated S_Λ values in the SD states are much smaller than those in the ground states, unlike the result using the relativistic mean-field (RMF) calculation [B.-N. Lu et al., Phys. Rev. C, 89, 044307 (2014)]. One of the reasons for this difference between the present work and the RMF calculation is the difference in the density profile of the SD states in the core nuclei. We also find that the property of the Λ N odd-parity interaction affects the S_Λ trend between the ground and SD states.


    African Journals Online (AJOL)

    features suggest schistosomal contribution in the aetioiogy of bladder cancer in this region. in conclusion, this study reveals an association between chronic urinary schistosomiasis and carcinoma of the bladder in this region. Thc hospitai prevaience of this maiignancy shows a rising trend. REFERENCES. 1. FergussonAR.

  7. 40Ar/39Ar age calibration against counted annuallayers

    DEFF Research Database (Denmark)

    Storey, Michael; Stecher, Ole


    The 40Ar/39Ar method, based on the decay of the naturally occurring radioactive isotope 40K, is capable of producing ages with precision better than ± 0.1 %. However, accuracy is limited to no better than 1 % mainly due to the relatively large uncertainty in the 40K decay constants. One approach ...... correlated to the Icelandic peralkaline rhyolitic Thorsmörk ignimbrite. We will present preliminary 40Ar/39Ar results on the age of this eruption...

  8. Ars Electronica tulekul / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-


    6.-11. IX toimub Austrias Linzis "Ars Electronica" festival, mille teema on "Code - The Language of Our Time". Festivali kavast, osalejatest, ava-performance'ist "Europe - A Symphonic Vision", näitusest "Cyberarts 2003. Prix Ars Electronica"

  9. AR Sco observing campaign (United States)

    Waagen, Elizabeth O.


    Dr. Thomas Marsh (University of Warwick) and colleagues have requested AAVSO coverage of the intriguing binary AR Sco in support of upcoming Newton-XMM observations scheduled for 2016 September 10 15:41 - September 11 02:26 UT. This fascinating binary system is the subject of an exciting paper in the July 2016 issue of Nature (Marsh et al., 2016Natur.537..374M; pre-print version at arXiv ( Marsh writes of their research on AR Sco: " was down to [the amateurs [who are co-authors] on the paper that we got onto it in the first place. Coverage immediately before, after and (especially) during [the XMM observations] would be great. The most challenging aspect is the time resolution: ideally one wants a cadence Finder charts with sequence may be created using the AAVSO Variable Star Plotter ( Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.


    Directory of Open Access Journals (Sweden)



    Full Text Available Stemming is a main step used to process textual data. It is usually used in several types of applications such as: text mining, information retrieval (IR, and natural language processing (NLP. A major task in stemming is to standardize words; which can be achieved by reducing each word to its base (root or stem. Arabic stemming is not an easy task. Unlike other languages, Arabic language is a highly inflected language, since it uses many inflectional forms. Researchers are divided on the benefit of using stemming in fields of IR, NLP...etc., since in Arabic the morphological variants of a certain word are not always semantically related. The aim of this paper is to design and implement a new Arabic light stemmer (ARS which is not based on Arabic root patterns. Instead, it depends on well defined mathematical rules and several relations between letters. A series of tests were conducted on ARS stemmer to compare its effectiveness with the effectiveness of two other Arabic stemmers. Test shows clearly the effectiveness superiority of ARS compared to effectiveness of these two Arabic stemmers.

  11. Arándano:


    Jiménez-Bonilla, Vilma; Abdelnour-Esquivel, Ana


    Proyecto de Investigación: (VIE-5402-1510-9501) El arándano (Ericaceae, Vaccinium spp) es una baya de color oscuro, azulada. Constituye una de las fuentes más importantes de antocianos y carotenoides que le confieren propiedades antioxidantes. Sus frutas son de bajo valor calórico, ricas en vitamina C, potasio, hierro y calcio. Hay seis especies nativas en nuestro territorio, que se distribuyen en un rango altitudinal entre 1500 y 3500 m.s.n.m., en los bosques montanos de la cordillera de...

  12. ARS-Media for excel instruction manual (United States)

    ARS-Media for Excel Instruction Manual is the instruction manual that explains how to use the Excel spreadsheet ARS-Media for Excel application. ARS-Media for Excel Instruction Manual is provided as a pdf file....

  13. Ars Poetica : [luuletused] / Mats Traat

    Index Scriptorium Estoniae

    Traat, Mats, 1936-


    Sisu: Ars poetica ; Veepeegel ; Kontrollõed ; Mandariiniriik ; Nikolai Siamashvili (1888-1911) ; Kolmekümne kolmas aasta ; Kiri linast 1966 ; Italmaz Nuriyev ; Rudolf Rimmelile mõeldes ; Gennadi Aigi

  14. The ArDM experiment

    CERN Document Server

    Haranczyk, M; Badertscher, A; Boccone, V; Bourgeois, N; Bueno, A; Carmona-Benitez, M C; Chorowski, M; Creus, W; Curioni, A; Daw, E; Degunda, U; Dell'Antone, A; Droge, M; Epprecht, L; Haller, C; Horikawa, S; Kaufmann, L; Kisiel, J; Knecht, L; Laffranchi, M; Lagoda, J; Lazzaro, C; Lightfoot, P; Lozano, J; Lussi, D; Maire, G; Mania, S; Marchionni, A; Mavrokoridis, K; Melgarejo, A; Mijakowski, P; Natterer, G; Navas-Concha, S; Otiougova, P; Piotrowska, A; Polinski, J; de Prado, M; Przewlocki, P; Ravat, S; Regenfus, C; Resnati, F; Robinson, M; Rochet, J; Romero, L; Rondio, E; Rubbia, A; Scotto-Lavina, L; Spooner, N; Viant, T; Trawinski, A; Ulbricht, J; Zalewska, A


    The aim of the ArDM project is the development and operation of a one ton double-phase liquid argon detector for direct Dark Matter searches. The detector measures both the scintillation light and the ionization charge from ionizing radiation using two independent readout systems. This paper briefly describes the detector concept and presents preliminary results from the ArDM R&D program, including a 3 l prototype developed to test the charge readout system.

  15. Feldspar 40Ar/39Ar dating of ICDP PALEOVAN cores (United States)

    Engelhardt, Jonathan Franz; Sudo, Masafumi; Stockhecke, Mona; Oberhänsli, Roland


    Volcaniclastic fall deposits in ICDP drilling cores from Lake Van, Turkey, contain sodium-rich sanidine and calcium-rich anorthoclase, which both comprise a variety of textural zoning and inclusions. An age model records the lake's history and is based on climate-stratigraphic correlations, tephrostratigraphy, paleomagnetics, and earlier 40Ar/39Ar analyses (Stockhecke et al., 2014b). Results from total fusion and stepwise heating 40Ar/39Ar analyses presented in this study allow for the comparison of radiometric constraints from texturally diversified feldspar and the multi-proxy lacustrine age model and vice versa. This study has investigated several grain-size fractions of feldspar from 13 volcaniclastic units. The feldspars show textural features that are visible in cathodoluminescence (CL) or back-scattered electron (BSE) images and can be subdivided into three dominant zoning-types: (1) compositional zoning, (2) round pseudo-oscillatory zoning and (3) resorbed and patchy zoning (Ginibre et al., 2004). Round pseudo-oscillatory zoning records a sensitive alternation of Fe and Ca that also reflects resorption processes. This is only visible in CL images. Compositional zoning reflects anticorrelated anorthite and orthoclase contents and is visible in BSE. Eleven inverse isochron ages from total fusion and three from stepwise heating analyses fit the age model. Four experiments resulted in older inverse isochron ages that do not concur with the model within 2σ uncertainties and that deviate from 1 ka to 17 ka minimum. C- and R-type zoning are interpreted as representing growth in magma chamber cupolas, as wall mushes, or in narrow conduits. Persistent compositions of PO-type crystals and abundant surfaces recording dissolution features correspond to formation within a magma chamber. C-type zoning and R-type zoning have revealed an irregular incorporation of melt and fluid inclusions. These two types of zoning in feldspar are interpreted as preferentially

  16. Analysis list: AR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available AR Blood,Breast,Prostate + hg19 http:...//,,,http:

  17. Analysis list: Ar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Ar Gonad,Kidney,Prostate + mm9 http:...//,,,http:/

  18. ARS-Media for Excel (United States)

    ARS-Media for Excel is an ion solution calculator that uses Microsoft Excel to generate recipes of salts for complex ion mixtures specified by the user. Generating salt combinations (recipes) that result in pre-specified target ion values is a linear programming problem. Thus, the recipes are genera...

  19. Projection Mapping Technologies for AR


    Iwai, Daisuke


    This invited talk will present recent projection mapping technologies for augmented reality. First, fundamental technologies are briefly explained, which have been proposed to overcome the technical limitations of ordinary projectors. Second, augmented reality (AR) applications using projection mapping technologies are introduced.

  20. "Ars Electronica 2009" / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-


    30. "Ars Electronica" festival "Human Nature" ("Inimese loomus") Linzis. Osaka ülikooli professori Hiroshi Ishiguro mehaanilis-digitaalsest nukust. Hübriidkunsti kategoorias peapreemia saanud Eduardo Kaci inimtaimest. Konverentsidest. Näitusest "See this Sound", mis oli pühendatud helile kujutavas kunstis

  1. AR DOC: Augmented reality documentaries

    DEFF Research Database (Denmark)

    Vistisen, Peter


    Augmented Reality Documentaries (AR DOC) er et ’lille’ Shareplay projekt (ansøgte midler augmented reality cross media løsninger, til at skabe engagerende publikumsformidling...... indenfor oplevelsesindustrien. Projektet har genereret ny viden omkring, hvordan fysisk og digital formidling kan understøttes via Augmented Reality som formidlingsformat....

  2. USDA-ARS Quartlerly News (United States)

    This quarterly article is an update of research going on at The USDA-ARS Thad Cochran Southern Horticultural Laboratory in Poplarville, MS to be published in the Louisiana Nursery and Landscape Associations (LANLA) quarterly newsletter. This is one of three publications that I am sending out to the ...

  3. Book review: Advances in 40Ar/39Ar dating: From archaeology to planetary sciences (United States)

    Cosca, Michael A.


    The recently published book Advances in 40Ar/39Ar Dating: From Archaeology to Planetary Sciences is a collection of 24 chapters authored by international scientists on topics ranging from decay constants to 40Ar/39Ar dating of extraterrestrial objects. As stated by the editors in their introduction, these chapters were assembled with the goal of providing technique-specific examples highlighting recent advances in the field of 40Ar/39Ar dating. As this is the first book truly dedicated to 40Ar/39Ar dating since the second edition printing of the argon geochronologist’s handbook Geochronology and Thermochronology by the 40Ar/39Ar Method (McDougall and Harrison 1999), a new collection of chapters highlighting recent advances in 40Ar/39Ar geochronology offers much to the interested reader.

  4. $\\beta$ decay of $^{47}$Ar

    CERN Document Server

    Weissman, L; Bergmann, U C; Brown, B A; Catherall, R; Cederkäll, J; Dillmann, I; Hallmann, O; Fraile-Prieto, L M; Franchoo, S; Gaudefroy, L; Köster, U; Kratz, K L; Pfeiffer, B; Sorlin, O; 10.1103/PhysRevC.70.024304


    Information on beta -decay properties of neutron-rich /sup 47/Ar was obtained at the ISOLDE facility at CERN using isobaric selectivity. This was achieved by a combination of a plasma-ion source with a cooled transfer line and subsequent mass separation. A doubly charged beam was used in order to improve the signal-to-background ratio associated with multi-charged noble gas fission products. The identification of the /sup 47/Ar gamma -ray transitions was performed by comparing the spectra obtained from direct proton bombardment of the target and of the neutron converter. New excited levels in the daughter /sup 47/K nucleus corresponding to the negative-parity states were observed. The obtained data are compared to the result of large-scale shell model calculations and quasiparticle random-phase approximation predictions. (29 refs).

  5. ARS - Helsinki - 2006 / Galina Balashova

    Index Scriptorium Estoniae

    Balashova, Galina


    Steven Holli projekteeritud Kiasma muuseumihoonest Helsingis. Kontseptuaalkunsti näitusest ARS 06 "Reaalsustunne" Kiasmas. Eestlastest esineb Mark Raidpere. Vene kunstnikegrupi AEC+F ja vene kunstnike Juri Vassiljevi ning Aleksandr Ponomarjovi töödest näitusel. Ka Gerda Steineri & Jörg Lenzlingeri (Šveits), Martin & Munoz'i (USA, Hispaania), arvutigraafik Charles Sandisoni (SB), videokunstnik Bill Viola (USA) jt. töödest

  6. 39Ar-40Ar chronology of the enstatite chondrite parent bodies (United States)

    Hopp, Jens; Trieloff, Mario; Ott, Uli; Korochantseva, Ekaterina V.; Buykin, Alexey I.


    Ar-Ar isochron ages of EL chondrites suggest closure of the K-Ar system at 4.49 ± 0.01 Ga for EL5 and 6 chondrites, and 4.45 ± 0.01 Ga for EL3 MAC 88136. The high-temperature release regimes contain a mixture of radiogenic 40Ar* and trapped primordial argon (solar or Q-type) with 40Ar/36ArTR ~ 0, which does not affect the 40Ar budget. The low-temperature extractions show evidence of an excess 40Ar component. The 40Ar/36Ar is 180-270; it is defined by intercept values of isochron regression. Excess 40Ar is only detectable in petrologic types >4/5. These lost most of their primordial 36Ar from low-temperature phases during metamorphism and retrapped excess 40Ar. The origin of this excess 40Ar component is probably related to metamorphic Ar mobilization, homogenization of primordial and in situ radiogenic Ar, and trapping of Ar by distinct low-temperature phases. Ar-Ar ages of EH chondrites are more variable and show clear evidence of a major impact-induced partial resetting at about 2.2 Ga ago or alternatively, prolonged metamorphic decomposition of major K carrier phases. EH impact melt LAP 02225 displayed the highest Ar-Ar isochron age of 4.53 ± 0.01 Ga. This age sets a limit of about 25-45 Ma for the age bias between the K-Ar and U-Pb decay systems.

  7. Ars Memorativa, Ars Oblivionis in Middle English Religious Plays

    Directory of Open Access Journals (Sweden)

    Ciobanu Estella Antoaneta


    Full Text Available This paper investigates the multi-layered violence of religious representation in the late medieval York biblical plays, with a focus on the Supper at Emmaus. I read Emmaus (Y40, a play which commemorates the Crucifixion and openly encourages strong anti-Judaism, alongside scenes in an early predecessor pageant, The Crucifixion (Y35, within their contemporary devotional and mnemonic practices, i.e. the confessional Book of Margery Kempe and Thomas Bradwardine’s tract on ars memorativa. Emmaus in particular demonstrates how a fundamentally violent ars memorativa, the legacy of ancient rhetoric to the Middle Ages, also underpins the instruction of the laity in the basics of Christian faith, here with the aid of highly musical prosody and repetition, and thereby hones a biased, intolerant and violence-inured Christian collective memory. To study the York play’s position relative to late medieval mnemonic practices, I frame my analysis within memory studies, enriched with the more specific insights offered by social-psychological, neurobiological and cognitivist studies of memory.

  8. The ideal imaging AR waveguide (United States)

    Grey, David J.


    Imaging waveguides are a key development that are helping to create the Augmented Reality revolution. They have the ability to use a small projector as an input and produce a wide field of view, large eyebox, full colour, see-through image with good contrast and resolution. WaveOptics is at the forefront of this AR technology and has developed and demonstrated an approach which is readily scalable. This paper presents our view of the ideal near-to-eye imaging AR waveguide. This will be a single-layer waveguide which can be manufactured in high volume and low cost, and is suitable for small form factor applications and all-day wear. We discuss the requirements of the waveguide for an excellent user experience. When enhanced (AR) viewing is not required, the waveguide should have at least 90% transmission, no distracting artifacts and should accommodate the user's ophthalmic prescription. When enhanced viewing is required, additionally, the waveguide requires excellent imaging performance, this includes resolution to the limit of human acuity, wide field of view, full colour, high luminance uniformity and contrast. Imaging waveguides are afocal designs and hence cannot provide ophthalmic correction. If the user requires this correction then they must wear either contact lenses, prescription spectacles or inserts. The ideal imaging waveguide would need to cope with all of these situations so we believe it must be capable of providing an eyebox at an eye relief suitable for spectacle wear which covers a significant range of population inter-pupillary distances. We describe the current status of our technology and review existing imaging waveguide technologies against the ideal component.

  9. GPS-Based AR Games Development Potential

    Directory of Open Access Journals (Sweden)

    Gregorius Alvin Raditya Santoso


    Full Text Available The application of new technologies in a game is not a new thing. One example is the application of Augmented Reality (AR technology in game. Many people do not know the application of AR technology in game, although the application of this technology is able to produce a game with unique gameplay. In addition, since AR game is GPS-based, it offers new gaming experience, that is, playing outdoors in which the real world becomes the game arena. This advantage gives the AR technology a huge potential to be developed into a game

  10. A Refined Astronomically Calibrated 40Ar/39Ar Age for Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian


    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the Fish Canyon sanidine (FCs) neutron fluence...... monitor, by multi-collector noble gas mass spectrometry, through cross-calibration with A1 tephra sanidines (A1Ts) of the direct astronomically tuned Faneromeni section (Crete). The astronomically intercalibrated 40Ar/39Ar age of FCs of 28.172±0.028 Ma (2σ, external errors) is within the uncertainty of......, but more precise (±0.10%) than, the previous 40Ar/39Ar age determined by intercalibration with astronomically tuned tephras from the Melilla Basin (Morocco). Using this proposed age for FCs, combined with measurements using the A1Ts as the neutron fluence monitor, a weighted mean Bishop Tuff 40Ar/39Ar...

  11. 40Ar/39Ar age spectra of some undisturbed terrestrial samples (United States)

    Brent, Dalrymple G.; Lanphere, M.A.


    40Ar/39Ar age spectra and 40Ar/36Ar vs 39Ar/36Ar isochrons were determined by incremental heating for 11 terrestrial rocks and minerals whose geology indicates that they represent essentially undisturbed systems. The samples include muscovite, biotite, hornblende, sanidine, plagioclase, dacite, diabase and basalt and range in age from 40 to 1700 m.y. For each sample, the 40Ar/39Ar ratios, corrected for atmospheric and neutron-generated argon isotopes, are the same for most of the gas fractions released and the age spectra, which show pronounced plateaus, thus are consistent with models previously proposed for undisturbed samples. Plateau ages and isochron ages calculated using plateau age fractions are concordant and appear to be meaningful estimates of the crystallization and cooling ages of these samples. Seemingly anomalous age spectrum points can be attributed entirely to small amounts of previously unrecognized argon loss and to gas fractions that contain too small (less than 2 per cent) a proportion of the 39Ar released to be geologically significant. The use of a quantitative abscissa for age spectrum diagrams is recommended so that the size of each gas fraction is readily apparent. Increments containing less than about 4-5 per cent of the total 39Ar released should be interpreted cautiously. Both the age spectrum and isochron methods of data reduction for incremental heating experiments are worthwhile, as each gives slightly different but complementary information about the sample from the same basic data. Use of a least-squares fit that allows for correlated errors is recommended for 40Ar/36Ar vs 39Ar/36Ar isochrons. The results indicate that the 40Ar/39Ar incremental heating technique can be used to distinguish disturbed from undisturbed rock and mineral systems and will be a valuable geochronological tool in geologically complex terranes. ?? 1994.

  12. USDA/ARS Organic Production Research (United States)

    For much of its history, USDA/ARS had little to do with research on organic agriculture, however research in organic systems has made considerable gains at the agency over the past decade. In the 1980's and 1990's, as the organic food industry was taking off, ARS researchers who wanted to serve orga...

  13. The effect of SEM imaging on the Ar/Ar system in feldspars (United States)

    Flude, S.; Sherlock, S.; Lee, M.; Kelley, S. P.


    Complex microtextures form in K-feldspar crystals as they cool and are affected by deuteric alteration. This complex structure is the cause of variable closure temperatures for Ar-Ar, a phenomenon which has been utilized in multi domain diffusion (MDD) modelling to recover thermal histories [1]. However, there has been substantial controversy regarding the precise interaction between feldspar microtextures and Ar-diffusion [2,3]. A number of studies have addressed this issue using coupled SEM imaging and Ar/Ar UV laser ablation microprobe (UV-LAMP) analysis on the same sample, to enable direct comparison of microtextures with Ar/Ar age data [4]. Here we have tested the idea that SEM work may affect Ar/Ar ages, leading to inaccurate results in subsequent Ar/Ar analyses. Three splits of alkali feldspar from the Dartmoor Granite in SW England were selected for Ar/Ar UV-LAMP analysis. Split 1 (“control”) was prepared as a polished thick section for Ar/Ar analysis. Split 2 (“SEM”) was prepared as a polished thick section, was chemically-mechanically polished with colloidal silica and underwent SEM imaging (uncoated) and focussed ion beam (FIB) milling (gold coated); electron beam damage in the SEM was maximised by leaving the sample at high magnification for eight minutes. Split 3 (“Etch”) is a cleavage fragment that was etched with HF vapour and underwent low to moderate magnification SEM imaging. The control split gave a range of laser-spot ages consistent with the expected cooling age of the granite and high yields of radiogenic 40Ar* (>90%). The area of the “SEM” split that experienced significant electron beam damage gave younger than expected ages and 40Ar* yields as low as 57%. These are interpreted as a combination of implantation of atmospheric Ar and local redistribution of K within the sample. The area of “SEM” that underwent FIB milling gave ages and 40Ar* yields comparable to the control split, suggesting that the Au-coat minimises FIB

  14. 40Ar/39Ar Ages of Carbonaceous Xenoliths in 2 HED Meteorites (United States)

    Turrin, B.; Lindsay, F. N.; Park, J.; Herzog, G. F.; Delaney, J. S.; Swisher, C. C., III; Johnson, J.; Zolensky, M.


    The generally young K/Ar and 40Ar/39Ar ages of CM chondrites made us wonder whether carbonaceous xenoliths (CMX) entombed in Howardite–Eucrite–Diogenite (HED) meteorites might retain more radiogenic 40Ar than do ‘free-range’ CM-chondrites. To find out, we selected two HED breccias with carbonaceous inclusions in order to compare the 40Ar/39Ar release patterns and ages of the inclusions with those of nearby HED material. Carbonaceous inclusions (CMXs) in two HED meteorites lost a greater fraction of radiogenic 40Ar than did surrounding host material, but a smaller fraction of it than did free-range CM-chondrites such as Murchison or more heavily altered ones. Importantly, however, the siting of the CMXs in HED matrix did not prevent the 40Ar loss of about 40 percent of the radiogenic 40Ar, even from phases that degas at high laboratory temperatures. We infer that carbonaceous asteroids with perihelia of 1 astronomical unit probably experience losses of at least this size. The usefulness of 40Ar/39Ar dating for samples returned from C-type asteroids may hinge, therefore, on identifying and analyzing separately small quantities of the most retentive phases of carbonaceous chondrites.

  15. Instrumentation development for In Situ 40Ar/39Ar planetary geochronology (United States)

    Morgan, Leah; Munk, Madicken; Davidheiser-Kroll, Brett; Warner, Nicholas H.; Gupta, Sanjeev; Slaybaugh, Rachel; Harkness, Patrick; Mark, Darren


    The chronology of the Solar System, particularly the timing of formation of extra-terrestrial bodies and their features, is an outstanding problem in planetary science. Although various chronological methods for in situ geochronology have been proposed (e.g., Rb-Sr, K-Ar), and even applied (K-Ar), the reliability, accuracy, and applicability of the 40Ar/39Ar method makes it by far the most desirable chronometer for dating extra-terrestrial bodies. The method however relies on the neutron irradiation of samples, and thus a neutron source. Herein, we discuss the challenges and feasibility of deploying a passive neutron source to planetary surfaces for the in situ application of the 40Ar/39Ar chronometer. Requirements in generating and shielding neutrons, as well as analysing samples are described, along with an exploration of limitations such as mass, power and cost. Two potential solutions for the in situ extra-terrestrial deployment of the 40Ar/39Ar method are presented. Although this represents a challenging task, developing the technology to apply the 40Ar/39Ar method on planetary surfaces would represent a major advance towards constraining the timescale of solar system formation and evolution.

  16. Ars Baltica-verkoston puheenjohtajuus Suomeen Risto Ruohoselle

    Index Scriptorium Estoniae


    1990. a. loodud võrgustiku Ars Baltica sekretariaat (Ars Baltica Contact Point & Communication Center) tuleb Kielist Tallinnasse Eesti kultuuriministeeriumi kuni aastani 2002 (Suur-Karja 23). Ars Baltica (ühendus)

  17. Infrared scintillation in liquid Ar and Xe

    NARCIS (Netherlands)

    Bressi, G; Carugno, G.; Conti, E; Iannuzzi, D; Meneguzzo, AT


    Infrared emission induced by ionizing particle has been observed in liquid Ar and liquid Xe. The phenomenon seems to be similar to the one recently observed in dense noble gases. (C) 2000 Elsevier Science B.V. All rights reserved.

  18. Stark broadening parameter tables for Ar VIII

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.


    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 9 Ar VIII transitions as a function of temperature and perturber density.

  19. "Ars Ornata" Mediterrania / Kadri Mälk

    Index Scriptorium Estoniae

    Mälk, Kadri, 1958-


    VI rahvusvaheline ehtekunstinäitus "Ars Ornata" juuni lõpus Barcelonas. Konverentsist, peanäitusest (osalejad Eestist), ehtekunstiõpetust andvast kõrgkoolist Escola Massana'st Barcelonas, õppejõude. Eesti ehtekunsti tulevikust.

  20. Ars ornata / Kadri Mälk

    Index Scriptorium Estoniae

    Mälk, Kadri, 1958-


    V rahvusvaheline ehtekunsti konverents 'Ars ornata Europeana' juuni lõpus Stockholmis. New Yorgis elava kuraatori Charon Kranseni ja prantsuse ehtekunstniku Christophe Burger' juhitud vestlusringidest. 1997. a. Pariisis loodud International Craft Design Association'ist (ICDA).

  1. ARS 01 Helsingi Kiasmas / Tarmo Virki

    Index Scriptorium Estoniae

    Virki, Tarmo


    Helsingis Kiasmas avatud rahvusvahelisest kunstinäitusest ARS 01 alapealkirjaga "Avanevaid perspektiive", kus esines oma töödega ka Marko Mäetamm. Näituse raames toimuvast Santiago Sierra kunstiprojektist kodututega

  2. The Measurement of Ion Drift Velocities in Presheaths in Ar and He-Ar Plasmas (United States)

    Wang, Xu; Ko, Eunsuk; Hershkowitz, Noah


    The presheath is a region of weak electric field that accelerates ions into the sheath at the plasma boundary. Presheath measurements were carried out near a plate 15cm in diameter mounted in a multi-dipole DC plasma with pure Ar and He-Ar gas mixtures (P_total >= 1.0mTorr, ne >= 1E9cm-3, Te boxcar averager, ion drift velocity profiles were obtained in pure Ar plasma with different neutral pressures and the relationship between Ar and He ion drift velocities was determined in He-Ar plasma respectively. Using Ar ion drift velocities from LIF data ^[1], the He ion drift velocities were determined. Measurements by launching a continuous sinusoidal wave and a pulse are compared. ** Work supported by US DOE grant DE-FG02-97ER54437 [1] G. D. Severn, Xu Wang, Eunsuk Ko and N. Hershkowitz, Phys. Rev. Lett. 90, 145001 (2003).

  3. AR4VI: AR as an Accessibility Tool for People with Visual Impairments (United States)

    Coughlan, James M.; Miele, Joshua


    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness – an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a range of accessibility barriers. Rather than being restricted to use by people with visual impairments, AR4VI is a compelling universal design approach offering benefits for mainstream applications as well. PMID:29303163

  4. AR4VI: AR as an Accessibility Tool for People with Visual Impairments. (United States)

    Coughlan, James M; Miele, Joshua


    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness - an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a range of accessibility barriers. Rather than being restricted to use by people with visual impairments, AR4VI is a compelling universal design approach offering benefits for mainstream applications as well.

  5. Ar-Ar Thermochronlogy of Apollo 12 Impact-Melt Breccia 12033,638-1 (United States)

    Crow, C. A.; Cassata, W. S.; Jolliff, B. L.; Ziegler, R. A.; Borg, L. E.; Shearer, C. K.


    We have undertaken an Ar-Ar thermochronology investigation as part of a coordinated multichronometer analysis of a single Apollo 12 impact- melt breccia to demonstrate the wide range of information that can be obtained for a single complex rock. This has implications for the age of formation, component makeup, and subsequent impact/shock and exposure history of the sample. This study also serves as a capabilities demonstration for the proposed MoonRise Mission [1]. The goal of this investigation is to elucidate the history of this sample through coordinated 40Ar*/39Ar, Sm-Nd, Rb-Sr and zircon 207Pb-206Pb ages along with geochemical and petrographic context on a relatively small (approximately 450 mg) sample. Here, we report preliminary results of the Ar-Ar thermochronology.

  6. High Spatial Resolution 40Ar/39Ar Geochronology of Lunar Impact Melt Rocks (United States)

    Mercer, Cameron Mark

    Impact cratering has played a key role in the evolution of the solid surfaces of Solar System bodies. While much of Earth’s impact record has been erased, its Moon preserves an extensive history of bombardment. Quantifying the timing of lunar impact events is crucial to understanding how impacts have shaped the evolution of early Earth, and provides the basis for estimating the ages of other cratered surfaces in the Solar System. Many lunar impact melt rocks are complex mixtures of glassy and crystalline “melt” materials and inherited clasts of pre-impact minerals and rocks. If analyzed in bulk, these samples can yield complicated incremental release 40Ar/39Ar spectra, making it challenging to uniquely interpret impact ages. Here, I have used a combination of high-spatial resolution 40Ar/39Ar geochronology and thermal-kinetic modeling to gain new insights into the impact histories recorded by such lunar samples. To compare my data to those of previous studies, I developed a software tool to account for differences in the decay, isotopic, and monitor age parameters used for different published 40Ar/39Ar datasets. Using an ultraviolet laser ablation microprobe (UVLAMP) system I selectively dated melt and clast components of impact melt rocks collected during the Apollo 16 and 17 missions. UVLAMP 40Ar/39Ar data for samples 77135, 60315, 61015, and 63355 show evidence of open-system behavior, and provide new insights into how to interpret some complexities of published incremental heating 40Ar/39Ar spectra. Samples 77115, 63525, 63549, and 65015 have relatively simple thermal histories, and UVLAMP 40Ar/39Ar data for the melt components of these rocks indicate the timing of impact events—spanning hundreds of millions of years—that influenced the Apollo 16 and 17 sites. My modeling and UVLAMP 40Ar/39Ar data for sample 73217 indicate that some impact melt rocks can quantitatively retain evidence for multiple melt-producing impact events, and imply that such

  7. 40Ar-39Ar age of a lava flow from the Bhimashankar Formation ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    the St. Mary's Islands volcanics, southern India: record of India-Madagascar breakup on the Indian subcontinent;. Earth Planet. Sci. Lett. 139 39–46. Pande K, Venkatesan T R, Gopalan K, Krishnamurthy P and Macdougall J D 1988. 40. Ar-. 39. Ar ages of alkali basalts from Kutch, Deccan volcanic province, India; Geol. Soc.

  8. A refined astronomically calibrated 40Ar/39Ar age for Fish Canyon sanidine

    NARCIS (Netherlands)

    Rivera, T.A.; Storey, M.; Zeeden, C.; Hilgen, F.J.; Kuiper, K.


    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the FishCanyon sanidine (FCs) neutron fluence monitor,

  9. 40Ar/36Ar geochronology on a quadrupole mass spectrometer: Where are we going? (United States)

    Schneider, B.; Wijbrans, J. R.; Kuiper, K. F.; Fenton, C. R.; Williams, A. J.


    40Ar/39Ar analysis has passed many milestones since its first application (Wänke & König, 1959). From the early all-glass Reynolds-type vacuum system to today's high quality, bakeable all-metal piping and valve systems, the evolution of ultra high vacuum systems has been considerable. Extraction systems have faced similar changes over time. Early furnaces made partially of glass were later replaced by full metal constructs containing a high temperature resistant molybdenum alloy tube and heating mechanism, sometimes contained within an insulating secondary vacuum chamber. Laser extraction techniques further refined the approach allowing very small samples or sample parts to be analyzed. The principal type of mass spectrometer used for 40Ar/36Ar geochronology is the magnetic sector instrument, which has the resolution and sensitivity necessary for measuring argon isotopes and achieving high precision over a large age range. We present 40Ar/39Ar data from basalt samples collected from a number of different locations, all obtained using the Hiden HAL Series 1000 quadrupole mass spectrometer at Vrije University, Amsterdam. We show that quadrupole technology is not only a viable option in K-Ar geochronology (Rouchon et al., 2008) but also in 40Ar/39Ar geochronology. The data was obtained from groundmass hand-picked from 200-500 um size fractions. Sample amounts of 200 to 500 mg were used for incremental heating experiments. The quality of the data is demonstrated by convergence of plateau and isochron ages, replicate analyses and by comparison to results of independent studies. Sample ages range from 40 ka to 400 ka, demonstrating the potential of quadrupole instruments for dating even very young rocks using the 40Ar/39Ar incremental heating technique. Rouchon, V., Lefevre, J.-C., Quidelleur, X., Guerin, G., Gillot, P.-Y. (2008): Nonspiked 40Ar and 36Ar quantification using a quadrupole mass spectrometer: A potential for K-Ar geochronology. International Journal of

  10. Regulation of AR Degradation and Function by Ubiquitylation (United States)


    and epitope tagged ubiquitin. As expected, the input lanes showed that AR protein was increased by PP1 (Fig. 5B, left panel). We then...V5 epitoipe tag on AR). (B) PC3 cells stably expressing WT or K911R mutant AR were treated with vehicle or 10 nM DHT for 4 hours. AR binding to...C) HeLa cells were transfected with AR S650A mutant and (D) a LNCaP line was generated to stably express Flag- tagged AR-S650A construct. Cells in

  11. 40Ar/39Ar and unspiked 40K-40Ar dating of upper Pleistocene volcanic activity in the Bas-Vivarais (Ardèche, France) (United States)

    Sasco, Romain; Guillou, Hervé; Nomade, Sébastien; Scao, Vincent; Maury, René C.; Kissel, Catherine; Wandres, Camille


    Fifteen basanitic and tephritic flows from Bas-Vivarais, the youngest volcanic field in the French Massif Central together with the Chaîne des Puys, were dated by 40Ar/39Ar and 40K-40Ar on separated groundmass, and studied for paleomagnetism. An almost systematic discrepancy between the two types of ages is observed, the 40K-40Ar method providing ages up to 8.5 times the 40Ar/39Ar ones. Microscopic observations and geochemical analyses lead us to conclude that most of the K-Ar ages measured on Bas-Vivarais samples are in error due to extraneous argon originating from contamination by xenocrysts from disintegrated crustal and mantle xenoliths. However, 40Ar/39Ar experiments do not evidence any excess argon, suggesting two possibilities: 1, the extraneous argon contribution was eliminated during the pre-degassing of the samples at 600 °C prior to the step heating experiments, 2 - K-Ar ages may be older because larger quantities of xenocrysts, potential carriers of extraneous argon were involved in the K-Ar experiments than in the 40Ar/39Ar ones. 40Ar/39Ar ages are thus little or not affected by contamination and provide reliable ages for the studied volcanoes. Combined 40Ar/39Ar datings and magnetic directions for each flow point out to three successive stages in the volcanic evolution of Bas-Vivarais. Stage 1, limited to the northern part of the field, has a mean age of 187.3 ± 19.0 ka. In its southern part, Stages 2 and 3 emplaced magmas at 31.1 ± 3.9 ka and 23.9 ± 8.1 ka, respectively. These two last stages are consistent with available 14C dates but not with previous thermoluminescence data.

  12. Neogene Astrochronology: Applications For Ar/ar Dating and Sea-floor Spreading Rates (United States)

    Krijgsman, W.; Hilgen, F. J.; Kuiper, K.; Wijbrans, J. R.; Wilson, D. S.

    A recently developed method to construct geological time scales involves the cali- bration of sedimentary cycles, or other cyclic variations in the geological record, to computed time series of the quasi-periodic variations of the Earth's orbit. Following earlier tuning attempts for the Plio-Pleistocene, the astronomical (polarity) time scale (A(P)TS) is now well established for the last 13 million years. The astronomical time scale deviates considerably from earlier time scales based on K/Ar dating, but has sub- sequently been confirmed by radioisotopic ages using the Ar/Ar (single crystal) laser fusion technique. In this contribution we will present the state of the art results of our attempts to extend the Mediterranean-based APTS into the middle Miocene. For this extension we have used perfectly cyclic successions, derived from both marine and continental records. We will furthermore elaborate on the successful application of the APTS in studies of seafloor spreading history. In addition, we will show the lat- est progress made in the comparison of astronomical and Ar/Ar ages for volcanic ash layers that are intercalated in the cyclostratigraphic sequences of the Mediterranean Neogene. In this way the age of fluence monitor standards in radioisotopic (Ar/Ar) dating can be calibrated independently of absolute isotopic abundance measurements.

  13. KRYGSHELDEIW AR HEROES Dirkie Uys - Kinderheld

    African Journals Online (AJOL)

    KRYGSHELDEIW AR HEROES. Dirkie Uys - Kinderheld. W. Kroukamp*. Die Groot Trek bet tane belde opgelewer, maar die aangrypendste verbaal is die geskiedenis van die jong beld, Dirkie Uys. Op 11 April 1838 bet by 'n beldedood gestref nadat by sy vader teen 'n oormag. Zoeloekrygers verdedig bet. Vandag leef by ...

  14. High power Ar-Xe laser

    NARCIS (Netherlands)

    Witteman, W.J.; Gielkens, S.W.A.; Tskhai, V.N.; Peters, P.J.M.


    The discharge conditions of the multi-atmospheric e-beam sustained Ar-Xe laser are investigated. It is observed that the quasi-stationary period of a laser pulse depends on the e-beam current, the discharge power deposition and the gas density. The laser efficiency can be as high as 8%. The pulse

  15. "ARS 01", perspektiivide avamine / Helen Kivisoo

    Index Scriptorium Estoniae

    Kivisoo, Helen


    30. IX 2001-20. I 2002 Kiasmas kuuendat korda toimuvast rahvusvahelisest näitusest "ARS", kus Eestist osaleb Marko Mäetamm. Kuraatorid Tuula Arkio, Maaretta Jaukkuri, Patrik Nyberg, Jari-Pekka Vanhala. Teemaks "kolmas ruum". Näituse kajastamisest.

  16. The ChArMEx database (United States)

    Ferré, Hélène; Belmahfoud, Nizar; Boichard, Jean-Luc; Brissebrat, Guillaume; Cloché, Sophie; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Mière, Arnaud; Ramage, Karim; Vermeulen, Anne; Boulanger, Damien


    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project includes long term monitoring of environmental parameters , intensive field campaigns, use of satellite data and modelling studies. Therefore ChARMEx scientists produce and need to access a wide diversity of data. In this context, the objective of the database task is to organize data management, distribution system and services, such as facilitating the exchange of information and stimulating the collaboration between researchers within the ChArMEx community, and beyond. The database relies on a strong collaboration between ICARE, IPSL and OMP data centers and has been set up in the framework of the Mediterranean Integrated Studies at Regional And Locals Scales (MISTRALS) program data portal. ChArMEx data, either produced or used by the project, are documented and accessible through the database website: The website offers the usual but user-friendly functionalities: data catalog, user registration procedure, search tool to select and access data... The metadata (data description) are standardized, and comply with international standards (ISO 19115-19139; INSPIRE European Directive; Global Change Master Directory Thesaurus). A Digital Object Identifier (DOI) assignement procedure allows to automatically register the datasets, in order to make them easier to access, cite, reuse and verify. At present, the ChArMEx database contains about 120 datasets, including more than 80 in situ datasets (2012, 2013 and 2014 summer campaigns, background monitoring station of Ersa...), 25 model output sets (dust model intercomparison, MEDCORDEX scenarios...), a high resolution emission inventory over the Mediterranean... Many in situ datasets

  17. 40Ar ∗ loss in experimentally deformed muscovite and biotite with implications for 40Ar/ 39Ar geochronology of naturally deformed rocks (United States)

    Cosca, Michael; Stunitz, Holger; Bourgeix, Anne-Lise; Lee, John P.


    The effects of deformation on radiogenic argon ( 40Ar ∗) retentivity in mica are described from high pressure experiments performed on rock samples of peraluminous granite containing euhedral muscovite and biotite. Cylindrical cores, ˜15 mm in length and 6.25 mm in diameter, were drilled from granite collected from the South Armorican Massif in northwestern France, loaded into gold capsules, and weld-sealed in the presence of excess water. The samples were deformed at a pressure of 10 kb and a temperature of 600 °C over a period 29 of hours within a solid medium assembly in a Griggs-type triaxial hydraulic deformation apparatus. Overall shortening in the experiments was approximately 10%. Transmitted light and secondary and backscattered electron imaging of the deformed granite samples reveals evidence of induced defects and for significant physical grain size reduction by kinking, cracking, and grain segmentation of the micas. Infrared (IR) laser (CO 2) heating of individual 1.5-2.5 mm diameter grains of muscovite and biotite separated from the undeformed granite yield well-defined 40Ar/ 39Ar plateau ages of 311 ± 2 Ma (2σ). Identical experiments on single grains separated from the experimentally deformed granite yield results indicating 40Ar ∗ loss of 0-35% in muscovite and 2-3% 40Ar ∗ loss in biotite. Intragrain in situ ultraviolet (UV) laser ablation 40Ar/ 39Ar ages (±4-10%, 1σ) of deformed muscovites range from 309 ± 13 to 264 ± 7 Ma, consistent with 0-16% 40Ar ∗ loss relative to the undeformed muscovite. The in situ UV laser ablation 40Ar/ 39Ar ages of deformed biotite vary from 301 to 217 Ma, consistent with up to 32% 40Ar ∗ loss. No spatial correlation is observed between in situ40Ar/ 39Ar age and position within individual grains. Using available argon diffusion data for muscovite the observed 40Ar ∗ loss in the experimentally treated muscovite can be utilized to predict average 40Ar ∗ diffusion dimensions. Maximum 40Ar/ 39Ar ages

  18. 40Ar* loss in experimentally deformed muscovite and biotite with implications for 40Ar/39Ar geochronology of naturally deformed rocks (United States)

    Cosca, M.; Stunitz, H.; Bourgeix, A.-L.; Lee, J.P.


    The effects of deformation on radiogenic argon (40Ar*) retentivity in mica are described from high pressure experiments performed on rock samples of peraluminous granite containing euhedral muscovite and biotite. Cylindrical cores, ???15mm in length and 6.25mm in diameter, were drilled from granite collected from the South Armorican Massif in northwestern France, loaded into gold capsules, and weld-sealed in the presence of excess water. The samples were deformed at a pressure of 10kb and a temperature of 600??C over a period 29 of hours within a solid medium assembly in a Griggs-type triaxial hydraulic deformation apparatus. Overall shortening in the experiments was approximately 10%. Transmitted light and secondary and backscattered electron imaging of the deformed granite samples reveals evidence of induced defects and for significant physical grain size reduction by kinking, cracking, and grain segmentation of the micas.Infrared (IR) laser (CO2) heating of individual 1.5-2.5mm diameter grains of muscovite and biotite separated from the undeformed granite yield well-defined 40Ar/39Ar plateau ages of 311??2Ma (2??). Identical experiments on single grains separated from the experimentally deformed granite yield results indicating 40Ar* loss of 0-35% in muscovite and 2-3% 40Ar* loss in biotite. Intragrain in situ ultraviolet (UV) laser ablation 40Ar/39Ar ages (??4-10%, 1??) of deformed muscovites range from 309??13 to 264??7Ma, consistent with 0-16% 40Ar* loss relative to the undeformed muscovite. The in situ UV laser ablation 40Ar/39Ar ages of deformed biotite vary from 301 to 217Ma, consistent with up to 32% 40Ar* loss. No spatial correlation is observed between in situ 40Ar/39Ar age and position within individual grains. Using available argon diffusion data for muscovite the observed 40Ar* loss in the experimentally treated muscovite can be utilized to predict average 40Ar* diffusion dimensions. Maximum 40Ar/39Ar ages obtained by UV laser ablation overlap those

  19. Numerical Simulations of the Evolution of Solar Active Regions: the Complex AR12565 and AR12567 (United States)

    Dumitrache, C.


    We have performed numerical magnetohydrodynamic (MHD) simulations of two closed active regions (AR). The input magnetic field values were the coronal magnetic field computed as extrapolation coronal from observations of the photospheric magnetic field. The studied active regions, NOAA AR12565 and AR12567, were registered as different bipolar region. Our investigation, the 3D coronal extrapolations, as well as the numerical MHD experiments, revealed that actually they evolved together as a quadrupolar active region. The second region emerged later under the loops system of AR12565 and separated from this one. A natural current sheet formed between then and it plays an important role in the explosive events (flares and coronal mass ejections) occurrence.

  20. 40Ar-39Ar age of a lava flow from the Bhimashankar Formation ...

    Indian Academy of Sciences (India)

    39Ar age of a lava flow from the Bhimashankar Formation, Giravali Ghat, Deccan Traps. Kanchan Pande S K Pattanayak K V Subbarao P Navaneethakrishnan T R Venkatesan. Volume 113 Issue 4 December 2004 pp 755-758 ...

  1. 40Ar-39Ar age of carbonatite-alkaline magmatism in Sung Valley ...

    Indian Academy of Sciences (India)

    40Ar-39Ar analyses of one alkali pyroxenite whole rock and two phlogopite separates of calcite carbonatites from the Sung Valley carbonatite-alkaline complex, which is believed to be a part of the Rajmahal-Bengal-Sylhet (RBS) ood basalt province, yielded indistinguishable plateau ages of 108.8 ± 2.0 Ma, 106:4 ± 1.3 Ma ...

  2. The ChArMEx database (United States)

    Ferré, Hélène; Descloitres, Jacques; Fleury, Laurence; Boichard, Jean-Luc; Brissebrat, Guillaume; Focsa, Loredana; Henriot, Nicolas; Mastrorillo, Laurence; Mière, Arnaud; Vermeulen, Anne


    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project includes long term monitoring of environmental parameters, intensive field campaigns, use of satellite data and modelling studies. Therefore ChARMEx scientists produce and need to access a wide diversity of data. In this context, the objective of the database task is to organize data management, distribution system and services such as facilitating the exchange of information and stimulating the collaboration between researchers within the ChArMEx community, and beyond. The database relies on a strong collaboration between OMP and ICARE data centres and falls within the scope of the Mediterranean Integrated Studies at Regional And Locals Scales (MISTRALS) program data portal. All the data produced by or of interest for the ChArMEx community will be documented in the data catalogue and accessible through the database website: The database website offers different tools: - A registration procedure which enables any scientist to accept the data policy and apply for a user database account. - Forms to document observations or products that will be provided to the database in compliance with metadata international standards (ISO 19115-19139; INSPIRE; Global Change Master Directory Thesaurus). - A search tool to browse the catalogue using thematic, geographic and/or temporal criteria. - Sorted lists of the datasets by thematic keywords, by measured parameters, by instruments or by platform type. - A shopping-cart web interface to order in situ data files. At present datasets from the background monitoring station of Ersa, Cape Corsica and from the 2012 ChArMEx pre-campaign are available. - A user-friendly access to satellite products

  3. A natural laboratory for 40Ar/39Ar geochronology: ICDP cores from Lake Van, Turkey (United States)

    Engelhardt, Jonathan; Sudo, Masafumi; Oberhänsli, Roland


    Pore water samples from ICDP Paleovan cores indicate a limited pore water exchange within Quaternary lake sediments. The core's volcaniclastic sections bear unaltered K-rich ternary feldspar and fresh to altered glass shards of predominantly rhyolitic composition. Whereas applying the 40Ar/39Ar method on feldspars resulted in ages timing a late-stage crystallization, glass shards had the potential to date the eruption. Volcanic glass is prone to modifications such as hydrous alteration (palagonitization) and devitrification (Cerling et al., 1985). These modifications affect the glass' chemistry and challenge the application of the 40Ar/39Ar method. Gaining precise radiometric ages from two phases has the potential to strengthen a climate-stratigraphic age-model (Stockhecke et al., 2014), and to significantly increase the temporal resolution on the deposition of the lake sediments. Vice versa the core's previous age model has the ability to question the reliability of 40Ar/39Ar eruption ages derived from ternary feldspars and glass shards. Multi- and single-grain total fusion on alkali feldspars from six volcaniclastic deposits resulted in Pleistocene ages that are in good agreement with the predicted age model. Feldspar phenocrysts from three ashes in the core's youngest section yielded consistent isochron ages that are significantly older than the model's prediction. Several distinct stratigraphic and paleomagnetic time markers of similar stratigraphic positions contradict to the older radiometric dates (Stockhecke et al., 2014). Partial resorption features of inherited feldspar domains and the involvement of excess 40Ar indicate incomplete degassing of older domains. To evaluate the magmatic history of the different domains EMPA mappings of trace elements that could be interpreted as Ar diffusion couples are currently conducted. Geochronology on Paleovan cores offers unique opportunities to monitor the effect of alteration on the Ar-systematics of volcanic glass

  4. AR Alternative Splicing and Prostate Cancer Progression (United States)


    patients with castration-resistant prostate cancer. Cancer Res 2009;69:2912–8. 15. Culig Z, Bartsch G. Androgen axis in prostate cancer. J Cell Biochem...such as MLPA are useful for identifying deletions or duplications that involve probe-binding sites, this study has illustrated that unbiased...the AR locus is illustrated at the top. Paired-end sequence reads were mapped to the hg19 build of the human genome using Burrows --Wheeler Alignment

  5. Ar isotope analysis for K-Ar dating using two modified-VG5400 mass spectrometers. 1. Isotope dilution method

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Keisuke; Ogata, Atsumi; Miura, Y.N.; Yamaguchi, Kenji [Okayama Univ., Misasa, Tottori (Japan). Inst. for Study of the Earth`s Interior


    Two noble gas mass spectrometry systems (MS-I and MS-II) have been installed in 1989, one of which was designed in our laboratory for Ar isotope analysis to measure K-Ar age by isotope dilution method using {sup 38}Ar-spike. The whole system was modified and improved to obtain high quality Ar data. The improved system composed of an Ar extraction and purification line and a Modified-VG5400 mass spectrometer enables us to determine precise Ar isotope composition easily and speedily irrespective to operator`s skillfulness. Formulas calculating radiogenic {sup 40}Ar abundance, which takes account of correction for Ar isotopes of both spike and blank, are presented. For samples with young K-Ar age, formulas to estimate the radiogenic {sup 40}Ar abundance based on {sup 40}Ar/{sup 36}Ar ratio are also proposed. Replicate analyses on many K-Ar standard samples show that the system can be applicable to samples with ages ranging 0.01 to 1500 Ma without any systematic analytical errors. (author).

  6. 75 FR 29654 - Amendment of Class E Airspace; Manila, AR (United States)


    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Manila, AR AGENCY: Federal... Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila Municipal Airport, Manila, AR has made this action necessary to enhance the safety and management of Instrument Flight Rule...

  7. 75 FR 12162 - Class E Airspace; Manila, AR (United States)


    ... Federal Aviation Administration 14 CFR Part 71 Class E Airspace; Manila, AR AGENCY: Federal Aviation... Class E airspace at Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila... procedures at Manila Municipal Airport, Manila, AR. Airspace reconfiguration is necessary due to the...

  8. Integration of Mobile AR Technology in Performance Assessment (United States)

    Kuo-Hung, Chao; Kuo-En, Chang; Chung-Hsien, Lan; Kinshuk; Yao-Ting, Sung


    This study was aimed at exploring how to use augmented reality (AR) technology to enhance the effect of performance assessment (PA). A mobile AR performance assessment system (MARPAS) was developed by integrating AR technology to reduce the limitations in observation and assessment during PA. This system includes three modules: Authentication, AR…

  9. CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2

    National Research Council Canada - National Science Library

    Seo, Woo-Young; Jeong, Byong Chang; Yu, Eun Ji; Kim, Hwa Jin; Kim, Seok-Hyung; Lim, Joung Eun; Kwon, Ghee Young; Lee, Hyun Moo; Kim, Jeong Hoon


    .... We further showed that CCAR1 is required for recruitment of AR, MED1 and RNA polymerase II to the enhancers of AR target genes and for androgen-induced long-range prostate specific antigen enhancer-promoter interaction...

  10. The thermal history of the Lhasa Block, South Tibetan Plateau based on FTD and Ar-Ar dating

    CERN Document Server

    Yang, T F; Lo Chong Huah; Chung, S L; Tien, R L; Xu, R; Deng, W


    Twelve basement samples were collected from South Tibet Plateau for FTD and Ar-Ar analysis to demonstrate their uplifting history since Cenozoic era. The preliminary results from different minerals with different closure temperatures, including apatite and zircon for fission-track dating, and K-feldspar, biotite for Ar-Ar dating, show that at least four stages of thermal history can be recognized in the studied area.

  11. Paleozoic ages and excess 40Ar in garnets from the Bixiling eclogite in Dabieshan, China: New insights from 40Ar/ 39Ar dating by stepwise crushing (United States)

    Qiu, Hua-Ning; Wijbrans, J. R.


    The 40Ar/ 39Ar stepwise crushing technique is applied for the first time to date garnet from ultra-high-pressure metamorphic (UHPM) eclogites. Three garnet samples from the Bixiling eclogites analyzed by 40Ar/ 39Ar stepwise crushing yield regular, predictable age spectra, and a clear separation between excess 40Ar and concordant plateau and isochron ages. All three age spectra begin with high apparent ages followed by step by step decreasing ages, and finally age plateaux with apparent ages in the range from 427 ± 20 to 444 ± 10 Ma. The data points constituting the age plateaux yield excellent isochrons with radiogenic intercept ages ranging from 448 ± 34 to 459 ± 58 Ma, corresponding to initial 40Ar/ 36Ar ratios from 292.1 ± 4.5 to 294.5 ± 6.7, statistically indistinguishable from the modern air. The high initial ages are interpreted to derive from secondary fluid inclusions containing excess 40Ar, whereas the plateau ages are attributed to gas from small primary fluid inclusions without significant excess 40Ar. The plateau ages are interpreted to approximate the time of garnet growth during initial UHPM metamorphism. Phengite analyzed by laser stepwise heating yielded a complicated two-saddle age spectrum with a scattered isochron corresponding to age of 463 ± 116 Ma and initial 40Ar/ 36Ar ratio of 1843 ± 1740 indicative of the presence of extraneous 40Ar within phengite. These concordant isochron ages measured on minerals diagnostic of eclogite grade metamorphism strongly suggest that Dabie UHPM eclogites were first formed in the early Paleozoic, during the same event that caused the Qinling-Northern Qaidam Basin-Altyn Tagh eclogites.

  12. Ar + NO microwave plasmas for Escherichia coli sterilization

    Energy Technology Data Exchange (ETDEWEB)

    Hueso, Jose L; Rico, Victor J; Cotrino, Jose; Gonzalez-Elipe, Agustin R [Instituto de Ciencia de Materiales de Sevilla, Centro Mixto CSIC-Universidad de Sevilla, Centro de Investigaciones Cientificas Isla de la Cartuja, Avda. Americo Vespucio 49, 41092 Sevilla (Spain); Frias, Jose E [Instituto de BioquImica Vegetal y FotosIntesis (IBVF-CSIC). Centro de Investigaciones CientIficas Isla de la Cartuja. Avda Americo Vespucio, 49, 41092 Sevilla (Spain)], E-mail:


    Ar + NO microwave discharges are used for sterilization and the results are compared with additional experiments with Ar, O{sub 2} and N{sub 2}-O{sub 2} plasma mixtures. The NO{sup *} species produced in the Ar-NO mixtures remain up to long distances from the source, thus improving the sterilization efficiency of the process. E. coli individuals exposed to the Ar + NO plasma undergo morphological damage and cell lysis. Combined effects of etching (by O{sup *} and Ar{sup *} species) and UV radiation (from deactivation of NO{sup *} species) are responsible for the higher activity found for this plasma mixture. (fast track communication)

  13. MEIS1 functions as a potential AR negative regulator

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Liang [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Department of Urology, Civil Aviation General Hospital/Civil Aviation Medical College of Peking University, Beijing 100123 (China); Li, Mingyang [Department of Gastroenterology, Nan Lou Division, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Feng, Fan [Department of Pharmacy, General Hospital of Shenyang Military Command, Shenyang 110016 (China); Yang, Yutao [Beijing Institute for Neuroscience, Capital Medical University, Beijing 100069 (China); Hang, Xingyi [National Scientific Data Sharing Platform for Population and Health, Beijing 100730 (China); Cui, Jiajun, E-mail: [Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 (United States); Gao, Jiangping, E-mail: [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China)


    The androgen receptor (AR) plays critical roles in human prostate carcinoma progression and transformation. However, the activation of AR is regulated by co-regulators. MEIS1 protein, the homeodomain transcription factor, exhibited a decreased level in poor-prognosis prostate tumors. In this study, we investigated a potential interaction between MEIS1 and AR. We found that overexpression of MEIS1 inhibited the AR transcriptional activity and reduced the expression of AR target gene. A potential protein–protein interaction between AR and MEIS1 was identified by the immunoprecipitation and GST pull-down assays. Furthermore, MEIS1 modulated AR cytoplasm/nucleus translocation and the recruitment to androgen response element in prostate specific antigen (PSA) gene promoter sequences. In addition, MEIS1 promoted the recruitment of NCoR and SMRT in the presence of R1881. Finally, MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells. Taken together, our data suggests that MEIS1 functions as a novel AR co-repressor. - Highlights: • A potential interaction was identified between MEIS1 and AR signaling. • Overexpression of MEIS1 reduced the expression of AR target gene. • MEIS1 modulated AR cytoplasm/nucleus translocation. • MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells.

  14. AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

    Directory of Open Access Journals (Sweden)

    Michael T. Schweizer


    Full Text Available In the 1940s Charles Huggins reported remarkable palliative benefits following surgical castration in men with advanced prostate cancer, and since then the androgen receptor (AR has remained the main therapeutic target in this disease. Over the past couple of decades, our understanding of AR-signaling biology has dramatically improved, and it has become apparent that the AR can modulate a number of other well-described oncogenic signaling pathways. Not surprisingly, mounting preclinical and epidemiologic data now supports a role for AR-signaling in promoting the growth and progression of several cancers other than prostate, and early phase clinical trials have documented preliminary signs of efficacy when AR-signaling inhibitors are used in several of these malignancies. In this article, we provide an overview of the evidence supporting the use of AR-directed therapies in prostate as well as other cancers, with an emphasis on the rationale for targeting AR-signaling across tumor types.

  15. 40Ar/39Ar Dates from Cretaceous Bentonites in a Foreland Basin Setting, North Slope, Alaska (United States)

    Shimer, G.; Benowitz, J.; Layer, P. W.; Sliwinski, M. G.; McCarthy, P.; Hanks, C. L.


    Bentonite beds occur in marine and non-marine Cretaceous sedimentary rocks of the Colville foreland basin of Alaska's North Slope. Thirteen new 40Ar/39Ar ages of bentonite mineral separates recovered from cores and a single outcrop location in the Nanushuk, Seabee, and Tuluvak formations confirm that volcanic ash deposition began as early as the late Albian and was persistent throughout the Cenomanian-Turonian. The 40Ar/39Ar results provide more precise age control than established biostratigraphic boundaries, and are useful for the interpretation of the foreland basin sediments in the context of increasing temperatures and global sea levels during the mid to Late Cretaceous. 40Ar/39Ar age spectra from six samples (biotite, sanidine, and glass phases) show limited argon loss and are used to calculate plateau ages. A biotite age of of 102.6 × 1.5 Ma from the deltaic deposits of the upper Nanushuk Formation is one of only a few radioisotopic dates for that formation, and supports the biostratigraphic determination based on ammonite and bivalve fossils. The Nanushuk Formation date, combined with a biotite age of 98.2 × 0.8 Ma from the base of the overlying marine Seabee Formation, roughly brackets a major transgressive event on the central North Slope to just after the Albian-Cenomanian boundary (~100.5 Ma). The 98.2 × 0.8 Ma age for the base of the Seabee Formation is older than expected, as are three ages for the Tuluvak Formation (94.4 × 0.9; 96.2 × 2.0; 96.6 × 1.4 Ma). The major and trace element geochemistry of a sub-sample of six bentonites from exploration wells at Umiat, Alaska show a range in composition from andesitic to rhyolitic, with a continental arc source. The bentonites become more felsic from the late Albian (~102 Ma) to late Cenomanian (~94 Ma). A likely source for the bentonites is the Okhotsk-Chukotka Volcanic Belt (OCVB) of eastern Siberia, a continental arc which became active in the Albian and experienced episodes of effusivity throughout

  16. Finding Structure in the ArXiv (United States)

    Alemi, Alexander; Chachra, Ricky; Ginsparg, Paul; Sethna, James


    We applied machine learning techniques to the full text of the arXiv articles and report a meaningful low-dimensional representation of this big dataset. Using Google's open source implementation of the continuous skip-gram model, word2vec, the vocabulary used in scientific articles is mapped to a Euclidean vector space that preserves semantic and syntactic relationships between words. This allowed us to develop techniques for automatically characterizing articles, finding similar articles and authors, and segmenting articles into their relevant sections, among other applications.

  17. AR Alternative Splicing and Prostate Cancer Progression (United States)


    CTD), which harbors the AR ligand-binding domain (LBD) and transcrip- tional activation function 2 (AF2) co-regulator binding interface ( Matias et al...doi:10.1002/ humu.21138) Matias PM, Donner P, Coelho R, Thomaz M, Peixoto C, Macedo S, Otto N, Joschko S, Scholz P, Wegg A et al. 2000 Structural...before clustering on a single lane of a flowcell. The flowcell was loaded on a Genome Analyzer IIx (GAIIx, Illumina, San Diego, CA, USA) for paired

  18. Advancements in cosmogenic 38Ar exposure dating of terrestrial rocks (United States)

    Oostingh, K. F.; Jourdan, F.; Danišík, M.; Evans, N. J.


    Cosmogenic exposure dating of Ca-rich minerals using 38Ar on terrestrial rocks could be a valuable new dating tool to determine timescales of geological surface processes on Earth. Here, we show that advancement in analytical precision, using the new generation multi-collector ARGUSVI mass spectrometer on irradiated pyroxene and apatite samples, allows determination of cosmogenic 38Ar abundances above background values, as well as discrimination of 38Ar/36Ar ratios (1σ absolute precision of ±0.3%) from the non-cosmogenic background value. Four statistically significant cosmochron (38Ar/36Ar vs37Ar/36Ar) diagrams could be constructed for southeast Australian pyroxene samples from the Mt Elephant scoria cone for which a combined apparent exposure age of 313 ± 179 ka (2σ) was obtained when using a 38Ar production rate (Ca) of 250 atoms /g Ca/ yr. This exposure age overlaps within error with the known 40Ar/39Ar eruption age of 184 ± 15 ka (2σ). Although apatite shows much larger 38Ar abundances than pyroxene, our modelling and analyses of unirradiated apatite suggest that apatite suffers from both natural and reactor-derived chlorogenic as well as natural nucleogenic contributions of 38Ar. Hence, we suggest that cosmogenic 38Ar exposure dating on irradiated Ca-rich (and eventually K-rich), but Cl-free, terrestrial minerals is a potential valuable and accessible tool to determine geological surface processes on timescales of a few Ma. Calculations show that with the new generation multi-collector mass spectrometers an analytical uncertainty better than 5% (2σ) can be achieved on samples with expected exposure ages of >4 Ma.

  19. Light Curve Variations of AR Lacertae

    Directory of Open Access Journals (Sweden)

    Il-Seong Nha


    Full Text Available Sixteen unitary Light curves of AR Lac in B and V are made at Yonsei University Observatory in the period of 1980-1988. Some overview findings of light variations are made. (1 The light variations outside eclipse follow none of the wave migration patterns reported by previous investigators. (2 Complicated shapes outside eclipse are apparently much reduced in the light curves of 1983-1984. This suggests that, in the future, AR Lac has a chance to attain a normal state with mo complicated interactions. (3 The depths of the primary and the secondary mid-eclipses are changing year-to-year. (4 The K0 star, the larger component, has brightened by 0.m14 V, while the G2 star has shown a fluctuation of about 0.m05 in V. (5 The B-V values at primary mid-eclipse have no correlation with the depth variations. (6 Independently of the increase of maximum brightness, the B-V colors in the non-eclipsed phases changed slightly over the years.

  20. Astronomical calibration of 40Ar/39Ar reference minerals using high-precision, multi-collector (ARGUSVI) mass spectrometry (United States)

    Phillips, D.; Matchan, E. L.; Honda, M.; Kuiper, K. F.


    The new generation of multi-collector mass spectrometers (e.g. ARGUSVI) permit ultra-high precision (1%) in 40K decay constants and the ages of natural reference minerals that form the basis of the technique. For example, reported ages for widely used 40Ar/39Ar reference materials, such as the ca. 28 Ma Fish Canyon Tuff sanidine (FCTs) and the ca. 1.2 Ma Alder Creek Rhyolite sanidine (ACRs), vary by >1%. Recent attempts to independently calibrate these reference minerals have focused on K-Ar analyses of the same minerals and inter-comparisons with astronomically tuned tephras in sedimentary sequences and U-Pb zircon ages from volcanic rocks. Most of these studies used older generation (effectively single-collector) mass spectrometers that employed peak-jumping analytical methods to acquire 40Ar/39Ar data. In this study, we reassess the inter-calibration and ages of commonly used 40Ar/39Ar reference minerals Fish Canyon Tuff sanidine (FCTs), Alder Creek Rhyolite sanidine (ACRs) and Mount Dromedary biotite (MD2b; equivalent to GA-1550 biotite), relative to the astronomically tuned age of A1 Tephra sanidine (A1Ts), Faneromeni section, Crete (Rivera et al., 2011), using a multi-collector ARGUSVI mass spectrometer. These analyses confirm the exceptional precision capability (0.1% in the 40Ar/39Ar ages of reference minerals without consideration of recoil artefacts, thus limiting the benefits of high precision multi-collector analyses. Significant improvement to the accuracy of the 40Ar/39Ar method (<0.1%) will require further inter-laboratory 40Ar/39Ar studies utilizing multi-collector mass spectrometry, additional constraints on recoil 39ArK loss from reference minerals, further resolution of discrepancies between astronomically tuned sedimentary successions and refinement of the 238U/206Pb zircon age cross-calibration approach.

  1. Mass spectrometric and Langmuir probe measurements in inductively coupled plasmas in Ar, CHF3/Ar and CHF3/Ar/O2 mixtures (United States)

    Kim, J. S.; Rao, M. V. V. S.; Cappelli, M. A.; Sharma, S. P.; Meyyappan, M.


    Absolute fluxes and energy distributions of ions in inductively coupled plasmas of Ar, CHF3/Ar, and CHF3/Ar/O2 have been measured. These plasmas were generated in a gaseous electronics conference cell modified for inductive coupling at pressures of 10-50 mTorr and 100-300 W of 13.56 MHz radio frequency (RF) power in various feed gas mixtures. In pure Ar plasmas, the Ar+ flux increases linearly with pressure as well as RF power. In mixtures, the Ar+ flux decreases with increase in pressure and CHF3 concentration in the mixture. The loss mechanism for Ar+ is attributed to resonance charge exchange (Ar+ + CHF3→products). Total ion flux in CHF3 mixtures decreases with increase in pressure and also CHF3 concentration. Relative ion fluxes observed in the present studies are analysed with the help of available cross sections for electron impact ionization and charge-exchange ion-molecule reactions. Measurements of plasma potential, electron and ion number densities, electron energy distribution function, and mean electron energy have also been made in the centre of the plasma with an RF-compensated Langmuir probe. Plasma potential values are compared with the mean ion energies determined from the measured ion energy distributions and are consistent. Electron temperature, plasma potential, and mean ion energy vary inversely with pressure, but increase with CHF3 content in the mixture.

  2. 40Ar/39Ar age of the Rotoiti Breccia and Rotoehu Ash, Okataina Volcanic Complex, New Zealand, and identification of heterogeneously distributed excess 40Ar in supercooled crystals

    DEFF Research Database (Denmark)

    Flude, Stephanie; Storey, Michael


    /39Ar stepped heating experiments on single K-feldspar crystals reveal the presence of heterogeneously distributed excess 40Ar, preferentially released at lower temperature steps (most likely from fluid/melt inclusions), which cannot reliably be characterised by, or corrected for using isotope...

  3. 40Ar-39Ar age of carbonatite-alkaline magmatism in Sung Valley ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging Solutions)

    Figure 2. Geological map of the Sung Valley carbonatite-alkaline complex (after Krishnamurthy 1985). the earliest measurements of fission track ages of. 80 ± 13Ma and 90 ± 10Ma on apatite by Chat- topadhyay and Hashimi (1984). More recent results of dating efforts are: 149 ± 5Ma (K-Ar age of phlogopite from carbonatite ...

  4. Identification of an AR mutation-negative class of androgen insensitivity by determining endogenous AR activity

    NARCIS (Netherlands)

    Hornig, N.C.; Ukat, M.; H.U. Schweikert (H.); O. Hiort (Olaf); Werner, R.; S.L.S. Drop (Stenvert); M.L. Cools (Martine); I.A. Hughes (Ieuan A.); L. Audí (Laura); S.F. Ahmed (Faisal); Demiri, J.; Rodens, P.; Worch, L.; Wehner, G.; Kulle, A.E.; Dunstheimer, D.; Müller-Roßberg, E.; T. Reinehr (Thomas); Hadidi, A.T.; Eckstein, A.K.; Van Der Horst, C.; Seif, C.; R. Siebert (Reiner); O. Ammerpohl (Ole); P-M. Holterhus (Paul-Martin)


    textabstractContext: Only approximately 85%of patients with a clinical diagnosis complete androgen insensitivity syndrome and less than 30%with partial androgen insensitivity syndrome can be explained by inactivating mutations in the androgen receptor (AR) gene. Objective: The objective of the study

  5. 40Ar/39Ar ages for the fossil-bearing Gyeongsang Supergroup in South Korea (United States)

    Chang, S. C.; Hemming, S. R.


    Since the 1970s, abundant vertebrate fossils have been documented from the Cretaceous Gyeongsang Supergroup in the Gyeongsang Basin and some small nearby basins of the Korean Peninsula, including dinosaurs, pterosaurs, crocodilians, turtles and fish. In addition to body fossils, well-preserved dinosaur, bird and pterosaur tracks have been found from these formations. Well-preserved and extensive vertebrate ichnofaunas from the Gyeongsang Supergroup represent the largest known concentration of Cretaceous vertebrate track sites reported from the Asian continent. Determining the age of the Gyeongsang Supergroup is critical to understanding several fundamental questions related to evolution and paleo-biogeography. However, limited radioisotopic studies for the Gyeongsang Supergroup have been previously reported. Additionally, the large uncertainties of previous data and the incomplete stratigraphic description of the samples limit their value for high-resolution chronostratigraphy. In this study, we aim to establish high-precision 40Ar/39Ar ages for two well-known tuffs from the middle and the upper part of the Gyeongsang Supergroup, and one rhyolite from the uppermost Gyeongsang Supergroup. Our preliminary 40Ar/39Ar data for the Kusandong Tuff indicates that the middle part of the Gyeongsang Supergroup is 78-82 Ma. This is consistent with the hypothesized extension of the Jehol biota into Korea and the preliminary results suggest that refinement of the time scale for these strata is a practical goal. The Gyeongsang Supergroup sample has great potential for substantially increasing our knowledge of Mesozoic terrestrial ecosystems.

  6. Eurekan deformation on Prins Karls Forland, Svalbard - new insights from Ar40/Ar39 muscovite dating (United States)

    Faehnrich, Karol; Schneider, David; Manecki, Maciej; Czerny, Jerzy; Myhre, Per Inge; Majka, Jarosław; Kośmińska, Karolina; Barnes, Christopher; Maraszewska, Maria


    Eurekan deformation has been proven to be a complex sequence of tectonic episodes, dominated by compression in the Circum Arctic region. It was associated with early Cenozoic collision of Eurasia, North America and Greenland plates producing fold-thrust belt style of deformation. Timing of this enigmatic event has not yet been extensively resolved by radiometric dating (Piepjohn et al. 2016, Journal of the Geological Society, 173(6), 1007-1024). Reinhardt et al. (2013, Z. Dt. Ges. Geowiss., 164 (1), 131-147) dated syn-tectonic volcanic ashes at c. 60 Ma and 54 Ma on Ellesmere Island, Canada. Tagner et al. (2011, Earth and Planetary Science Letters, 303(3), 203-214) interpreted c. 49-47 Ma 40Ar/39Ar ages on trachyte flows in northern Greenland as peak compression during the Eurekan event. On Svalbard, Tessensohn et al. (2001, Geologisches Jahrbuch, B 91, 83-104) reported K/Ar whole rock ages ranging from c. 67 to 49 Ma for the slates from Svartfjella-Eidembukta-Daudmannsodden Lineament. Bentonite layers in the Central Tertiary Basin are as young as c. 56 Ma (Charles et al. 2011, Geochem. Geophys. Geosyst., 12, 1-19), predating latest deformation. Moreover, Barnes et al (2017, in prep.) applied (U-Th)/He thermochronology along the western margin of Svalbard and resolved Early to Middle Eocene heating, likely documenting burial related to thrusting. Here we present new results from 40Ar/39Ar muscovite dating of ductile to brittle shear zone on Prins Karls Forland, Svalbard, indicating Eurekan age of thrusting. Prins Karls Forland is dominated by Neoproterozoic siliciclastic metasediments (comprising Caledonian basement) regionally metamorphosed to greenschist facies conditions. A ˜1 km wide ductile to brittle shear zone (the Bouréefjellet shear zone) separates the amphibolite facies Pinkie Unit from the lower grade upper structural unit, the Grampianfjella Formation (Faehnrich et al. 2016, EGU 2016). The age of the amphibolite facies metamorphism (c. 370-355 Ma

  7. Enseñar a ser

    Directory of Open Access Journals (Sweden)

    García Barreno, Pedro


    Full Text Available El «Informe Delors», cuyo texto fue presentado hace ahora diez años, señala que cualquier proyecto educativo para el siglo XXI debe contemplar dos acciones. «Enseñar a conocer, a hacer, a vivir juntos, a ser», y garantizar el acceso de todos a ello. El siglo que concluyó apenas media docena de años, ha estado cargado de inmensas paradojas: entre grandes males, extraordinarios logros y no pocas esperanzas inalcanzadas. Marcado por dos guerras mundiales, por genocidios, por la acelerada degradación de la biosfera o por la miseria de una masa de marginados frente al creciente bienestar de los privilegiados.…

  8. Simulation of Extreme Arctic Cyclones in IPCC AR5 Experiments (United States)


    Final Technical Report: "Simulation of Extreme Arctic Cyclones in IPCC AR5 Experiments" PI: Stephen Vavrus Nelson Institute Center for Climatic...June 2012: "Simulation of extreme Arctic cyclones in IPCC AR5 experiments", Breckenridge, CO. Oral presentation at the AGU Fall Meeting, December 2012...34Simulation of extreme Arctic cyclones in IPCC AR5 experiments", San Francisco, CA. Poster presentation at the World Climate Research Program (WCRP

  9. β -delayed three-proton decay of 31Ar (United States)

    Lis, A. A.; Mazzocchi, C.; Dominik, W.; Janas, Z.; Pfützner, M.; Pomorski, M.; Acosta, L.; Baraeva, S.; Casarejos, E.; Duénas-Díaz, J.; Dunin, V.; Espino, J. M.; Estrade, A.; Farinon, F.; Fomichev, A.; Geissel, H.; Gorshkov, A.; Kamiński, G.; Kiselev, O.; Knöbel, R.; Krupko, S.; Kuich, M.; Litvinov, Yu. A.; Marquinez-Durán, G.; Martel, I.; Mukha, I.; Nociforo, C.; Ordúz, A. K.; Pietri, S.; Prochazka, A.; Sánchez-Benítez, A. M.; Simon, H.; Sitar, B.; Slepnev, R.; Stanoiu, M.; Strmen, P.; Szarka, I.; Takechi, M.; Tanaka, Y.; Weick, H.; Winfield, J. S.


    The β decay of 31Ar , produced by fragmentation of an 36Ar beam at 880 MeV/nucleon, was investigated. Identified ions of 31Ar were stopped in a gaseous time projection chamber with optical readout allowing us to record decay events with emission of protons. In addition to β -delayed emission of one and two protons we clearly observed the β -delayed three-proton branch. The branching ratio for this channel in 31Ar is found to be 0.07 ±0.02 %.

  10. Acoustic resonance spectroscopy (ARS): ARS300 operations manual, software version 2.01

    Energy Technology Data Exchange (ETDEWEB)



    Acoustic Resonance Spectroscopy (ARS) is a nondestructive evaluation technology developed at the Los Alamos National Laboratory. The ARS technique is a fast, safe, and nonintrusive technique that is particularly useful when a large number of objects need to be tested. Any physical object, whether solid, hollow, or fluid filled, has many modes of vibration. These modes of vibration, commonly referred to as the natural resonant modes or resonant frequencies, are determined by the object`s shape, size, and physical properties, such as elastic moduli, speed of sound, and density. If the object is mechanically excited at frequencies corresponding to its characteristic natural vibrational modes, a resonance effect can be observed when small excitation energies produce large amplitude vibrations in the object. At other excitation frequencies, i.e., vibrational response of the object is minimal.

  11. New views on 40Ar/39Ar dating of high pressure rock exhumation: an example from Oman (United States)

    Warren, C. J.; Sherlock, S.; Kelley, S. P.


    40Ar/39Ar dating has long been considered an unreliable method for determining cooling ages of high pressure terranes as a result of the common (though not ubiquitous) presence of excess argon. New advances in analytical techniques now allow 40Ar/39Ar spots and traverses to be measured within different zones of individual mica grains, thereby creating the possibility of measuring intra-grain age changes in order to determine spatial and temporal variations of excess argon in the micas. We will present phengite single grain fusion and intra-grain UV laser 40Ar/39Ar data from a variety of rocks of different composition and metamorphic grade from Saih Hatat, NE Oman. This high pressure terrane, subducted and exhumed during the Late Cretaceous obduction of the Semail Ophiolite Complex, provides ideal material for testing and refining models of subduction-exhumation mechanisms. Single-grain 40Ar/39Ar fusion data from the highest grade phengites fall into two distinct groups. Chemically growth-zoned phengites from the mafic eclogites and surrounding calcareous and quartz schists yield a spread of ages from 80-120 Ma within individual samples, equal to the complete range of previously reported bulk 40Ar/39Ar (mainly step-heating) ages. By comparison, chemically homogeneous phengites from the interlayered eclogite-facies pelitic schists yield a single age population, with mean ages of ca. 80 Ma, similar to the previously reported 79 Ma U-Pb zircon age. The difference between the 40Ar/39Ar cooling age and the U-Pb crystallisation age indicates either remarkably rapid cooling or the presence of some excess argon. However the tight grouping of ages suggests that the excess argon is distributed similarly in each grain. The combination of these data with zircon U-Pb ages and phengite major- element chemistry, allow us to begin quantifying the behaviour of argon in high pressure phengites, and potentially determine better constrained timescales for orogenic cycling.

  12. Spatial autocorrelation method using AR model; Kukan jiko sokanho eno AR model no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H.; Obuchi, T.; Saito, T. [Iwate University, Iwate (Japan). Faculty of Engineering


    Examination was made about the applicability of the AR model to the spatial autocorrelation (SAC) method, which analyzes the surface wave phase velocity in a microtremor, for the estimation of the underground structure. In this examination, microtremor data recorded in Morioka City, Iwate Prefecture, was used. In the SAC method, a spatial autocorrelation function with the frequency as a variable is determined from microtremor data observed by circular arrays. Then, the Bessel function is adapted to the spatial autocorrelation coefficient with the distance between seismographs as a variable for the determination of the phase velocity. The result of the AR model application in this study and the results of the conventional BPF and FFT method were compared. It was then found that the phase velocities obtained by the BPF and FFT methods were more dispersed than the same obtained by the AR model. The dispersion in the BPF method is attributed to the bandwidth used in the band-pass filter and, in the FFT method, to the impact of the bandwidth on the smoothing of the cross spectrum. 2 refs., 7 figs.

  13. The infrared spectrum of the benzene-Ar cation

    NARCIS (Netherlands)

    Satink, R. G.; Piest, H.; von Helden, G.; Meijer, G.


    The infrared (IR) absorption spectra of the jet-cooled C6H6 and C6D6 cations, complexed with Ar, are measured throughout the 450-1500 cm(-1) region via IR-laser-induced vibrational dissociation spectroscopy. The IR spectrum of the C6H6-Ar cation is dominated by a Fermi resonance between the IR

  14. Aspects of What Makes or Breaks a Museum AR Experience

    DEFF Research Database (Denmark)

    Madsen, Claus B.; Madsen, Jacob Boesen; Morrison, Ann


    The paper critically evaluates central aspects of an iPad AR application developed for a museum context. The application is designed for children aged 8 to 12 and mixes AR and mini-game elements to convey dramatized historical events. The game has been deployed for roughly 3 months and the findings...

  15. 40Ar/39Ar and (U-Th)/He model age signatures of elusive Mercurian and Venusian meteorites (United States)

    Jourdan, Fred; Eroglu, Ela


    No meteorites from Mercury and Venus have been conclusively identified so far. In this study, we develop an original approach based on extensive Monte Carlo simulations and diffusion models to explore the radiogenic argon (40Ar*) and helium (4He*) loss behavior and the range of 40Ar/39Ar and (U-Th)/He age signatures expected for a range of crystals if meteorites from these planets were ever to be found. We show that we can accurately date the crystallization age of a meteorite from both Mercury and Venus using the 40Ar/39Ar technique on clinopyroxene (± orthopyroxene) and that its 40Ar/39Ar age should match the Pb-Pb age. At the surface of Mercury, phases like albite and anorthite will exhibit a complete range of 40Ar* loss ranging from 0% to 100%, whereas merrillite and apatite will show 100% 4He* loss. By measuring the crystal size and diffusion parameters of a series of plagioclase crystals, one can inverse the 40Ar* loss value to estimate the maximum temperature experienced by a rock, and narrow down the possible pre-ejection location of the meteorite at the surface of Mercury. At the surface of Venus, plagioclase and phosphate phases will only record the age of ejection. The (U-Th)/He systematics of merrillite and apatite will be, respectively, moderately and strongly affected by 4He* loss during the transit of the meteorite from its host planet to Earth. Finally, meteorites from Mercury or Venus will each have their own 40Ar/39Ar and (U-Th)/He isotopic age and 38Arc cosmic ray exposure age signatures over a series of different crystal types, allowing to unambiguously recognize a meteorite for any of these two planets using radiogenic and cosmogenic noble gases.

  16. Weighted Quantile Regression for AR model with Infinite Variance Errors. (United States)

    Chen, Zhao; Li, Runze; Wu, Yaohua


    Autoregressive (AR) models with finite variance errors have been well studied. This paper is concerned with AR models with heavy-tailed errors, which is useful in various scientific research areas. Statistical estimation for AR models with infinite variance errors is very different from those for AR models with finite variance errors. In this paper, we consider a weighted quantile regression for AR models to deal with infinite variance errors. We further propose an induced smoothing method to deal with computational challenges in weighted quantile regression. We show that the difference between weighted quantile regression estimate and its smoothed version is negligible. We further propose a test for linear hypothesis on the regression coefficients. We conduct Monte Carlo simulation study to assess the finite sample performance of the proposed procedures. We illustrate the proposed methodology by an empirical analysis of a real-life data set.

  17. Carbon isotope stratigraphy, magnetostratigraphy, and 40Ar/39Ar age of the Cretaceous South Atlantic coast, Namibe Basin, Angola

    NARCIS (Netherlands)

    Strganac, Christopher; Salminen, Johanna; Jacobs, Louis L.; Polcyn, Michael J.; Ferguson, Kurt M.; Mateus, Octávio; Schulp, Anne S.; Morais, Maria Luísa; Tavares, Tatiana da Silva; Gonçalves, António Olímpio


    We present the δ13C and paleomagnetic stratigraphy for marine strata at the coast of southern Angola, anchored by an intercalated basalt with a whole rock 40Ar/39Ar radiometric age of 84.6 ± 1.5 Ma, being consistent with both invertebrate and vertebrate biostratigraphy. This is the first African

  18. High-precision 40Ar/39Ar age for the Jehol Biota (United States)

    Chang, S.; Zhang, H.; Renne, P. R.; Fang, Y.


    Abundant fossils of the terrestrial Jehol Biota, including plants, insects, dinosaurs, birds, mammals and freshwater invertebrates, were discovered from the Yixian Formation and the overlying Jiufotang Formation in Inner Mongolia, Hebei Province and Liaoning Province, northeastern China. Because of the exceptional preservation of fossils, the Jehol Biota is one of the most important Mesozoic fossil outcrops and referred to as a "Mesozoic Pompeii". The Jehol Biota has provided a rare opportunity to address questions about the origin of birds, the evolution of feathers and flight, the early diversification of angiosperms and the timing of the radiation of placental mammals. The Tuchengzi Formation, which lies unconformably just below the Yixian Formation and consists mainly of variegated sandstones, is less fossiliferous than the two overlying formations. However, dinosaur tracks, silicified wood and compressed plants are found in this formation. A systematic 40Ar/39Ar dating of the Yixian and the Jiufotang formations was undertaken to provide a framework for understanding the timing and duration of the Jehol Biota and evolutionary events represented within it. Furthermore, determining the absolute age of the Tuchengzi Formation provides information to interpret abundant dinosaur tracks within and provide better age constrains for the beginning of the Jehol Biota. Here we present robust high-precision 40Ar/39Ar data for six tuff samples and two basalt samples collected from the Tuchengzi, the Yixian and the Jiufotang formations near the classic outcrops in western Liaoning, NE China. We obtain an age of 139.5 ± 1.0 Ma for the uppermost Tuchengzi Formation, an age of 129.7 ± 0.5 Ma for a basaltic lava from the bottom of the Yixian Formation and an age of 122.1 ± 0.3 Ma for a tuff from the base of the overlying Jiufotang Formation. Our data indicate that the Yixian Formation was deposited during the Early Cretaceous, the Barremian to early Aptian, within a time span

  19. The effects of retrograde reactions and of diffusion on 39Ar-40Ar ages of micas

    DEFF Research Database (Denmark)

    Allaz, Julien; Engi, Martin; Berger, Alfons


    /K and Cl/K ratios) did not change and the resulting ages can be interpreted unambiguously. In mineral separates containing two white micas, Ca/K and Cl/K ratios were variable, reflecting non-simultaneous laboratory degassing of the two heterochemical Ar-reservoirs. These ratios were used to identify each...... and remains stable during retrogression. In this case, muscovite and paragonite yield indistinguishable ages around 16.5 Ma. Above 590 °C, paragonite was mostly consumed to form plagioclase (>590 °C), whereby the relic mica yields an age up to 5.6 Ma younger than muscovite. This is interpreted to reflect...

  20. The development of AR book for computer learning (United States)

    Phadung, Muneeroh; Wani, Najela; Tongmnee, Nur-aiynee


    Educators need to provide the alternative educational tools to foster learning outcomes of students. By using AR technology to create exciting edutainment experiences, this paper presents how augmented reality (AR) can be applied in the education. This study aims to develop the AR book for tenth grade students (age 15-16) and evaluate its quality. The AR book was developed based on ADDIE framework processes to provide computer learning on software computer knowledge. The content was accorded with the current Thai education curriculum. The AR book had 10 pages in three topics (the first was "Introduction," the second was "System Software" and the third was "Application Software"). Each page contained markers that placed virtual objects (2D animation and video clip). The obtained data were analyzed in terms of average and standard deviation. The validity of multimedia design of the AR book was assessed by three experts in multimedia design. A five-point Likert scale was used and the values were X¯ =4 .84 , S.D. = 1.27 which referred to very high. Moreover, three content experts, who specialize in computer teaching, evaluated the AR book's validity. The values determined by the experts were X¯ =4 .69 , S.D. = 0.29 which referred to very high. Implications for future study and education are discussed.

  1. Inductively Coupled Plasma Etching of III-V Antimonides in BCl(3)/Ar and Cl(2)/Ar

    Energy Technology Data Exchange (ETDEWEB)

    Leavitt, R.P.; Lester, L.F.; Shul, R.J.; Willison, C.G.; Zhang, L.


    Inductively coupled plasma (ICP) etching characteristics of GaSb and AIGaAsSb have been investigated in BC13/Ar and Clz/Ar plasmas. The etch rates and selectivity between GaSb and AIGaAsSb are reported as functions of plasma chemistry, ICP power, RF self-bias, and chamber pressure. It is found that physical sputtering resorption of the etch products plays a dominant role in BC13/Ar ICP etching, while in Clz/Ar plasma, the chemical reaction dominates the etching. GaSb etch rates exceeding 2 ~rnhnin are achieved in Clz/Ar plasmas with smooth surfaces and anisotropic profiles. In BC13/Ar plasmas, etch rates of 5100 Mmin and 4200 Mmin are obtained for GaSb and AIGaAsSb, respectively. The surfaces of both GaSb and AIGaAsSb etched in BC13/Ar plasmas remain smooth and stoichiometric over the entire range of plasma conditions investigated. This result is attributed to effective removal of etch products by physical sputtering. For a wide range of plasma conditions, the selectivity between GaSb and AIGaAsSb is close to unity, which is desirable for fabricating etched mirrors and gratings for Sb-based mid-IR laser diodes.

  2. DNA damages induced by Ar F laser

    Energy Technology Data Exchange (ETDEWEB)

    Chapel, C.; Rose, S.; Chevrier, L.; Cordier, E.; Courant, D. [CEA Fontenay-aux-Roses, 92 (France). Dept. de Radiobiologie et de Radiopathologie


    The photo ablation process used in corneal refractive surgery by the Argon Fluoride (Ar F) laser emitting in ultraviolet C at 193 nm, exposes viable cells round the irradiated zone to sub ablative doses (< 400 joules.m -2). Despite that DNA absorption is higher at 193 nm than 254 nm, cytotoxicity of 193 nm laser radiation is lower than radiation emitted by 254 nm UV-C lamps. In situ, DNA could be protected of laser radiation by cellular components. Consequently, some authors consider that this radiation does not induce genotoxic effect whereas others suspect it to be mutagenic. These lasers are used for fifteen years but many questions remain concerning the long term effects on adjacent cells to irradiated area. The purpose of this study is to describe the effect of 193 nm laser radiation on DNA of stromal keratocytes which are responsible of the corneal structure. The 193 nm laser irradiation induces directly DNA breakage in keratocytes as it has been shown by the comet assay under alkaline conditions. Two hours post irradiation, damages caused by the highest exposure (150 J.m-2) are not repaired as it has been measured with the Olive Tail Moment (product of tail length and tail DNA content). They give partly evidence of induction of an apoptotic process in cells where DNA could be too damaged. In order to characterize specifically double strand breaks, a comparative analysis by immunofluorescence of the H2 Ax histone phosphorylation (H2 Ax) has been performed on irradiated keratocytes and unirradiated keratocytes. Results show a dose dependent increase of the number of H2 Ax positive cells. Consequences of unrepaired DNA lesions could be observed by the generation of micronuclei in cells. Results show again an increase of micronuclei in laser irradiated cells. Chromosomal aberrations have been pointed out by cytogenetic methods 30 mn after irradiation. These aberrations are dose dependent (from 10 to 150 J.m-2). The number of breakage decreases in the long run

  3. Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells. (United States)

    Shafi, Ayesha A; Putluri, Vasanta; Arnold, James M; Tsouko, Efrosini; Maity, Suman; Roberts, Justin M; Coarfa, Cristian; Frigo, Daniel E; Putluri, Nagireddy; Sreekumar, Arun; Weigel, Nancy L


    Metastatic prostate cancer (PCa) is primarily an androgen-dependent disease, which is treated with androgen deprivation therapy (ADT). Tumors usually develop resistance (castration-resistant PCa [CRPC]), but remain androgen receptor (AR) dependent. Numerous mechanisms for AR-dependent resistance have been identified including expression of constitutively active AR splice variants lacking the hormone-binding domain. Recent clinical studies show that expression of the best-characterized AR variant, AR-V7, correlates with resistance to ADT and poor outcome. Whether AR-V7 is simply a constitutively active substitute for AR or has novel gene targets that cause unique downstream changes is unresolved. Several studies have shown that AR activation alters cell metabolism. Using LNCaP cells with inducible expression of AR-V7 as a model system, we found that AR-V7 stimulated growth, migration, and glycolysis measured by ECAR (extracellular acidification rate) similar to AR. However, further analyses using metabolomics and metabolic flux assays revealed several differences. Whereas AR increased citrate levels, AR-V7 reduced citrate mirroring metabolic shifts observed in CRPC patients. Flux analyses indicate that the low citrate is a result of enhanced utilization rather than a failure to synthesize citrate. Moreover, flux assays suggested that compared to AR, AR-V7 exhibits increased dependence on glutaminolysis and reductive carboxylation to produce some of the TCA (tricarboxylic acid cycle) metabolites. These findings suggest that these unique actions represent potential therapeutic targets.

  4. RadNet Air Data From Little Rock, AR (United States)

    This page presents radiation air monitoring and air filter analysis data for Little Rock, AR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  5. Eestlased ARS BALTICA 08-l Austrias / Jüri Hain

    Index Scriptorium Estoniae

    Hain, Jüri, 1941-


    Rahvusvaheline kunstinäitus "ARS BALTICA 08" Salzburgi näitusehoones Berchtoldvilla, kuraator Peter Rieder. Osalesid kunstnikud Eestist (Mare Vint, Marje Üksine, Andres Tolts, Tiiu Kirsipuu, Jüri Hain), Lätist, Leedust ja Soomest

  6. Chromosomal context and replication properties of ARS plasmids in ...

    Indian Academy of Sciences (India)

    ARS) elements function as plasmid as well as chromosomal replication origins in yeasts. As compared to ARSs, different chromosomal origins vary greatly in their efficiency and timing of replication probably due to their wider chromosomal ...

  7. Hydrothermal fluids, argon isotopes and mineralization ages of the Fankou Pb-Zn deposit in south China: Insights from sphalerite 40Ar/39Ar progressive crushing (United States)

    Jiang, Ying-De; Qiu, Hua-Ning; Xu, Yi-Gang


    Hydrothermal fluid geochemistry and mineralization timing are two important factors in the genesis of a hydrothermal deposit. 40Ar/39Ar analyses of fluid inclusions not only provide time constraints for the mineralization but also help to clarify the K-Ca-Cl-Ar characteristics for the ore-forming fluids. In this study, six sphalerite samples collected from the Fankou lead-zinc sulfide deposit are investigated by 40Ar/39Ar in vacuo crushing. Gases liberated from the early and late crushing steps exhibit distinct Ar isotopic compositions and 40Ar/39Ar apparent ages. Argon released in the early steps has much higher 40Ar and 38ArCl and lower 37ArCa contents than those in the late steps. The significant excess Ar (40ArE) extracted in the early crushing steps shows a strong correlation with 38ArCl with very high 40ArE/38ArCl ratios. In contrast, those of the late steps mainly consist of atmospheric Ar and K-correlated radiogenic Ar with a constant 40ArR/39ArK ratio and the atmospheric initial 40Ar/36Ar ratio. As a result, all samples yield similar declining age spectra: the fore segments with anomalously old apparent ages decline quickly in the early crushing steps and the rear ones are flat with concordant apparent ages in the late crushing steps. The data points of the early steps define linear correlations in plots of 40ArNA/39ArK vs. 38ArCl/39ArK and 38ArCl/40ArNA vs. 39ArK/40ArNA (NA for non-atmospheric) and most yield ages of 240-230 Ma. On the other hand, the data of the late steps always construct well-defined isochrons in the plots of 36ArA/40ArNA vs. 39ArK/40ArNA with consistent ages of ˜300 Ma. We interpret that gases released in the early steps were from the secondary fluid inclusions (SFIs) due to their distribution characteristics along cracks leading to be easily extracted, and those released in the later steps represented the contribution of the primary fluid inclusions (PFIs). The initial 40Ar/36Ar ratios of SFIs, much higher than the modern

  8. New 40Ar/39Ar eruption ages for the western Aeolian Arc, Southern Italy (United States)

    Creamer, J. B.; Calvert, A. T.; Spera, F. J.


    New 40Ar/39Ar ages are presented for the western Aeolian Arc, southern Italy which help constrain eruption frequency and revise the local uplift history through bracketing the timing of marine terrace formation. The islands of Alicudi, Filicudi, and Salina are late-Quaternary composite stratovolcanoes which feature basaltic to dacitic calc-alkaline and high-K series lavas and pyroclastics. These islands have been the focus of several geochronologic studies in the past but many open questions remain due to recently revised mapping, conflicting ages, and incomplete coverage of eruptive sequences. On Salina, a single new age constrains the previously undated Corvo volcano to 128.8 +/- 5.3 ka. On Filicudi, three new dates constrain the oldest exposed episodes of volcanism to ~200-205 ka, in good agreement with previous K/Ar ages. The age of an intervening marine terrace is constrained by these oldest units to c. 200 ka. Additionally there is one new date of 80.4 ± 9.4 ka on the youngest effusive eruption on Filicudi, a dacite dome that overlies the youngest marine terrace on the island. On Alicudi, five new dates constrain the oldest exposed units (Paleo Alicudi Synthem) to 167.4 ± 26.1 ka, the Scoglio Galera to Spano synthems between 64.1 ± 4.1 ka and 59.3 ± 1.3 ka, and confirm the youngest eruptions (Fillo dell'Arpa Fm) at 30.0 ± 0.7 ka. Importantly, an undated formation that overlies the 59.3 ka unit is cut by a marine terrace that was previously interpreted to be ~80 ka (MIS 5a highstand). This result calls into question the archipelago-wide age correlation of marine terraces attempted by Lucchi et al. 2008 since the youngest terrace on Alicudi is younger than eruptive units that overly all terraces on Filicudi. Previous work suggesting that marine terraces on Filicudi were formed during Marine Isotope Stages (MIS) 5a,c, and e is permitted by our new ages, but the oldest terrace ('Paleoshoreline B') on Filicudi was possibly formed during MIS 7 rather than MIS

  9. Ars Moriendi: Coping with death in the Late Middle Ages. (United States)

    Espi Forcén, Fernando; Espi Forcén, Carlos


    The Ars moriendi was a book written in the early 15th century with the goal of assisting friars in their work of helping the dying. The aim of our study was to review the current literature on the Ars Moriendi concerning the field of medicine, to analyze the psychological mechanisms for coping with death anxiety within Ars Moriendi, and to explore parallels between the strategies used in the medieval book and in contemporary literature about death and dying. A review of literature using Pubmed, EMBASE, JSTOR, Project MUSE, and the New York Public Library was undertaken first. The primary source was then interpreted from a medical/psychological point of view. Seven articles were selected by literature review. These works comment on the importance of the Ars Moriendi in its historical context and explore the possibility of retrieving the principles of the text in contemporary society. The original text of Ars Moriendi, the primary source, presents death as a relief from the sufferings of earthly life and a gateway to eternal glory. According to the author, a good death implied the triumph over five demonic temptations in agonizing people: a lack of faith, despair, impatience, pride and greed. Analyzed from a modern psychiatric perspective, the Ars Moriendi offers descriptions of behavioral manifestations compatible with delirium, mood and anxiety disorders that characterize people with terminal illnesses. Moreover, we also explored parallels between the strategies used to cope with death anxiety in the Late Middle Ages and in contemporary society.

  10. Improving the Precision of the Half Life of 34Ar (United States)

    Iacob, V. E.; Hardy, J. C.; Bencomo, M.; Chen, L.; Horvat, V.; Nica, N.; Park, H. I.


    Currently, precise ft-values measured for superallowed 0+ -->0+ β transitions provide the most accurate value for Vud, the up-down quark mixing element of the Cabibbo-Kobayashi-Maskawa (CKM) matrix. This enables the most demanding test of CKM unitarity, one of the pillars of the Standard Model. Further improvements in precision are possible if the ft values for pairs of mirror 0+ -->0+ transitions can be measured with 0.1% precision or better. The decays of 34Ar and 34Cl are members of such a mirror pair, but so far the former is not known with sufficient precision. Since our 2006 publication of the half-life of 34Ar, we have improved significantly our acquisition and analysis techniques, adding refinements that have led to increased accuracy. The 34Cl half-life is about twice that of 34Ar. This obscures the 34Ar contribution to the decay in measurements such as ours, which detected the decay positrons and was thus unable to differentiate between the parent and daughter decays. We report here two experiments aiming to improve the half-life of 34Ar: The first detected positrons as in but with improved controls; the second measured γ rays in coincidence with positrons, thus achieving a clear separation of 34Ar decay from 34Cl.

  11. Identified kaon production in Ar+Sc collisions at SPS energies arXiv

    CERN Document Server

    NA61/SHINE is a fixed target experiment at the CERN Super Proton Synchrotron. The main goals of the experiment are to discover the critical point of strongly interacting matter and to study the properties of the onset of deconfinement. In order to reach these goals, a study of hadron production properties is performed in nucleus-nucleus, proton-proton and proton-nucleus interactions as a function of collision energy and size of the colliding nuclei. In this talk, the newest preliminary results on kaon spectra produced in Ar+Sc collisions at three beam momenta (30A, 40A and 75A) will be shown. The distributions of transverse mass and rapidity will be compared with results of NA61/SHINE (p+p, Be+Be) and NA49 (Pb+Pb, C+C, Si+Si), as well as with available world data.

  12. Characteristics and 40Ar/39Ar geochronology of the Erdenet Cu-Mo deposit, Mongolia (United States)

    Kavalieris, Imants; Khashgerel, Bat-Erdene; Morgan, Leah; Undrakhtamir, Alexander; Borohul, Adiya


    50 to 200 m from the granodiorite porphyry contact, although D veins (and chalcopyrite) extend outward to the propylitic zone.The Erdenet porphyry system, was overprinted by advanced argillic alteration, which outcrops 2 km northwest of the pit, and forms a lithocap that extends over 10 × 2.5 km. It is characterized by residual quartz, andalusite, Na-Ca and K-alunite, diaspore, pyrophyllite, zunyite, topaz, dickite, and kaolinite. The upper part of the porphyry Cu-Mo deposit (removed by mining), comprised a bornite-chalcocite enriched zone up to 300 m thick with an average grade of 0.7 wt % Cu and up to 5 wt % Cu locally. Based on hypogene bornite-chalcocite mineral textures and high-sulfidation state mineralogy, the enriched zone is inferred to be of hypogene origin, but modified by supergene processes. Consequently, it may be related to formation of the lithocap.Previous Re-Os dates of 240.4 and 240.7 ± 0.8 Ma for molybdenite in quartz veins are comparable to new 40Ar/39Ar dates of 239.7 ± 1.6 and 240 ± 2 Ma for muscovite that envelops D veins. One 40Ar/39Ar date on K-alunite from the lithocap of 223.5 ± 1.9 Ma suggests that it may be about 16 m.y. younger than Erdenet, but this result needs to be verified by further dating.

  13. Combined U-Th/He and 40Ar/39Ar geochronology of post-shield lavas from the Mauna Kea and Kohala volcanoes, Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Aciego, S.M.; Jourdan, F.; DePaolo, D.J.; Kennedy, B.M.; Renne, P.R.; Sims, K.W.W.


    Late Quaternary, post-shield lavas from the Mauna Kea and Kohala volcanoes on the Big Island of Hawaii have been dated using the {sup 40}Ar/{sup 39}Ar and U-Th/He methods. The objective of the study is to compare the recently demonstrated U-Th/He age method, which uses basaltic olivine phenocrysts, with {sup 40}Ar/{sup 39}Ar ages measured on groundmass from the same samples. As a corollary, the age data also increase the precision of the chronology of volcanism on the Big Island. For the U-Th/He ages, U, Th and He concentrations and isotopes were measured to account for U-series disequilibrium and initial He. Single analyses U-Th/He ages for Hamakua lavas from Mauna Kea are 87 {+-} 40 ka to 119 {+-} 23 ka (2{sigma} uncertainties), which are in general equal to or younger than {sup 40}Ar/{sup 39}Ar ages. Basalt from the Polulu sequence on Kohala gives a U-Th/He age of 354 {+-} 54 ka and a {sup 40}Ar/{sup 39}Ar age of 450 {+-} 40 ka. All of the U-Th/He ages, and all but one spurious {sup 40}Ar/{sup 39}Ar ages conform to the previously proposed stratigraphy and published {sup 14}C and K-Ar ages. The ages also compare favorably to U-Th whole rock-olivine ages calculated from {sup 238}U - {sup 230}Th disequilibria. The U-Th/He and {sup 40}Ar/{sup 39}Ar results agree best where there is a relatively large amount of radiogenic {sup 40}Ar (>10%), and where the {sup 40}Ar/{sup 36}Ar intercept calculated from the Ar isochron diagram is close to the atmospheric value. In two cases, it is not clear why U-Th/He and {sup 40}Ar/{sup 39}Ar ages do not agree within uncertainty. U-Th/He and {sup 40}Ar/{sup 39}Ar results diverge the most on a low-K transitional tholeiitic basalt with abundant olivine. For the most alkalic basalts with negligible olivine phenocrysts, U-Th/He ages were unattainable while {sup 40}Ar/{sup 39}Ar results provide good precision even on ages as low as 19 {+-} 4 ka. Hence, the strengths and weaknesses of the U-Th/He and {sup 40}Ar/{sup 39}Ar methods are

  14. Accurate and precise 40Ar/39Ar dating by high-resolution, multi-collection, mass spectrometry

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU-Instruments......New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU......-Instruments multi-collector Noblesse noble gas mass spectrometer configured with a faraday detector and three ion-counting electron multipliers. The instrument has the capability to measure several noble gas isotopes simultaneously and to change measurement configurations instantaneously by the use of QUAD lenses...... (zoom optics). The Noblesse offer several advantages over previous generation noble gas mass spectrometers and is particularly suited for single crystal 40Ar/39Ar dating because of: (i) improved source sensitivity (ii) ion-counting electron multipliers, which have much lower signal to noise ratios than...

  15. Spectroscopic and electric dipole properties of Sr+Ar and SrAr systems including high excited states (United States)

    Hamdi, Rafika; Abdessalem, Kawther; Dardouri, Riadh; Al-Ghamdi, Attieh A.; Oujia, Brahim; Gadéa, Florent Xavier


    The spectroscopic properties of the fundamental and several excited states of Sr+Ar and SrAr, Van der Waals systems are investigated by employing an ab initio method in a pseudo-potential approach. The potential energy curves and the spectroscopic parameters are displayed for the 1–10 2Σ+, 1–6 2Π and 1–3 2Δ electronic states of the Sr+Ar molecule and for the 1–6 1Σ+, 1–4 3Σ+, 1–3 1,3Π and 1–3 1,3Δ states of the neutral molecule SrAr. In addition, from these curves, the vibrational levels and their energy spacing are deduced for Σ+, Π and Δ symmetries. The spectra of the permanent and transition dipole moments are studied for the 1,3Σ+ states of SrAr, which are considered to be two-electron systems and 2Σ+ states of the single electron Sr+Ar ion. The spectroscopic parameters obtained for each molecular system are compared with previous theoretical and experimental works. A significant correlation revealed the accuracy of our results.

  16. Accurate Laboratory Measurements of Vibration-Rotation Transitions of 36ArH^+ and 38ArH+ (United States)

    Cueto, Maite; Cernicharo, Jose; Herrero, Victor Jose; Tanarro, Isabel; Domenech, Jose Luis


    The protonated Ar ion 36ArH^+ has recently been identified in space, in the Crab Nebula, from Herschel spectra. Its R(0) and R(1) transitions lie at 617.5 and 1234.6 GHz, respectively, where atmospheric transmission is rather poor, even for a site as good as that of ALMA. As an alternative, especially after the end of the Herschel mission, rovibrational transitions of ArH^+ could be observed in absorption against bright background sources such as the galactic center, or other objects. We report on accurate laboratory wavenumber measurements of 19 lines of the v=1-0 band of 36ArH^+ and 38ArH^+, using a hollow cathode discharge cell, a difference frequency laser spectrometer and Ar with natural isotopic composition. Of those lines, only eight had been reported before and with much less accuracy. The data have also been used in a Dunham-type global fit of all published laboratory data (IR and sub-mm) of all isotopologues. Barlow et al., Science, 342, 1343 (2013) R.R. Filgueira and C.E. Blom, J. Mol. Spectrosc., 127, 279 (1988) M. Cueto et al, Astrophys. J. Lett, 783, L5 (2014)

  17. Functional Promiscuity of Homologues of the Bacterial ArsA ATPases

    Directory of Open Access Journals (Sweden)

    Rostislav Castillo


    Full Text Available The ArsA ATPase of E. coli plays an essential role in arsenic detoxification. Published evidence implicates ArsA in the energization of As(III efflux via the formation of an oxyanion-translocating complex with ArsB. In addition, eukaryotic ArsA homologues have several recognized functions unrelated to arsenic resistance. By aligning ArsA homologues, constructing phylogenetic trees, examining ArsA encoding operons, and estimating the probable coevolution of these homologues with putative transporters and auxiliary proteins unrelated to ArsB, we provide evidence for new functions for ArsA homologues. They may play roles in carbon starvation, gas vesicle biogenesis, and arsenic resistance. The results lead to the proposal that ArsA homologues energize four distinct and nonhomologous transporters, ArsB, ArsP, CstA, and Acr3.

  18. Acoustic Resonance Spectroscopy (ARS) Munition Classification System enhancements. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Vela, O.A.; Huggard, J.C.


    Acoustic Resonance Spectroscopy (ARS) is a non-destructive evaluation technology developed at the Los Alamos National Laboratory (LANL). This technology has resulted in three generations of instrumentation, funded by the Defense Special Weapons Agency (DSWA), specifically designed for field identification of chemical weapon (CW) munitions. Each generation of ARS instrumentation was developed with a specific user in mind. The ARS1OO was built for use by the U.N. Inspection Teams going into Iraq immediately after the Persian Gulf War. The ARS200 was built for use in the US-Russia Bilateral Chemical Weapons Treaty (the primary users for this system are the US Onsite Inspection Agency (OSIA) and their Russian counterparts). The ARS300 was built with the requirements of the Organization for the Prohibition of Chemical Weapons (OPCW) in mind. Each successive system is an improved version of the previous system based on learning the weaknesses of each and, coincidentally, on the fact that more time was available to do a requirements analysis and the necessary engineering development. The ARS300 is at a level of development that warrants transferring the technology to a commercial vendor. Since LANL will supply the computer software to the selected vendor, it is possible for LANL to continue to improve the decision algorithms, add features where necessary, and adjust the user interface before the final transfer occurs. This paper describes the current system, ARS system enhancements, and software enhancements. Appendices contain the Operations Manual (software Version 3.01), and two earlier reports on enhancements.

  19. 40Ar/39Ar dating of the Honghuaqiao Formation in SE China (United States)

    Chang, S.; Zhang, H.; Hemming, S. R.; Mesko, G. T.; Fang, Y.


    The Jehol Biota, defined as the characteristic Eosestheria-Ephemeropsis-Lycoptera assemblage (Grabau, 1923, Bulletin of the Geological Survey of China), is widely distributed in eastern and central Asia (Li et al., 1982, Acta Geologica Sinica; Chen, 1988, Acta Palaeontologica Sinica). Abundant and varied fossils of the terrestrial Jehol Biota, including plants, insects, dinosaurs, birds, mammals, and freshwater invertebrates, have been discovered from the Dabeigou, the Yixian and the Jiufotang Formations (or their correlative strata) in northeast China from the Liaoning and Hebei Provinces and Inner Mongolia (Chen and Jin, 1999, Acta Palaeontologica Sinica). In addition, strata that may be correlative with the classic Jehol fossil-bearing formations have been identified extensively in central and eastern China, the Korean Peninsula, Mongolia, and Siberia. In the past three decades mollusk, conchostracan, ostracod, insect, fish, and plant fossils from localities in southeastern China, interpreted as related to the Jehol biota of the northeast, have been found (Mateer and Chen, 1986, Cretaceous Research; Li, 2003, Chinese Science Bulletin; Chen, Li and Batten, 2007, Geological Journal). However, a detailed correlation between the classic Jehol outcrops and the more recently found localities to the South and West has yet to emerge. Volcanic rocks from the Honghuaqiao fossil-bearing Formation in Tuzhou City of eastern Anhui Province, southeastern China provide an excellent opportunity to rectify this situation. Preliminary results of a pilot study suggest that the Honghuaqiao Formation is equivalent to the Longwanshan Formation of Anhui Province, southeastern China and the Yixian Formation, northeastern China (Chang et al., 2009, AGU abstract). Initial 40Ar/39Ar results indicate that conchostracans from the upper Honghuaqiao Formation are approximately 130 Ma. Our ongoing work aims to establish a high-resolution chronostratigraphy for Tuzhou City in Anhui Province

  20. Model‐Based Analysis of the ZrO2 Etching Mechanism in Inductively Coupled BCl3/Ar and BCl3/CHF3/Ar Plasmas

    National Research Council Canada - National Science Library

    Kim, Mansu; Min, Nam‐Ki; Yun, Sun Jin; Lee, Hyun Woo; Efremov, Alexander M; Kwon, Kwang‐Ho


    The etching mechanism of ZrO 2 thin films and etch selectivity over some materials in both BCl 3 /Ar and BCl3/CHF3/Ar plasmas are investigated using a combination of experimental and modeling methods...

  1. Ab initio transport coefficients of Ar+ ions in Ar for cold plasma jet modeling (United States)

    Chicheportiche, A.; Lepetit, B.; Gadéa, F. X.; Benhenni, M.; Yousfi, M.; Kalus, R.


    Collision cross sections and transport coefficients are calculated for Ar+ ions, in the ground state 2P3/2 and in the metastable state 2P1/2, colliding with their parent gas. Differential and integral collision cross sections are obtained using a numerical integration of the nuclear Schrödinger equation for several published interaction potentials. The Cohen-Schneider semi-empirical model is used for the inclusion of the spin-orbit interaction. The corresponding differential collision cross sections are then used in an optimized Monte Carlo code to calculate the ion transport coefficients for each initial ion state over a wide range of reduced electric field. Ion swarm data results are then compared with available experimental data for different proportions of ions in each state. This allows us to identify the most reliable interaction potential which reproduces ion transport coefficients falling within the experimental error bars. Such ion transport data will be used in electrohydrodynamic and chemical kinetic models of the low temperature plasma jet to quantify and to tune the active species production for a better use in biomedical applications.

  2. Statistical simulation of photoresists at EUV and ArF (United States)

    Biafore, John J.; Smith, Mark D.; Mack, Chris A.; Thackeray, James W.; Gronheid, Roel; Robertson, Stewart A.; Graves, Trey; Blankenship, David


    Requirements of resist modeling strategies for EUV and low-k1 ArF nanolithography continue to become more stringent. Resist designers are consistently faced with the task of reducing exposure dose and line roughness while simultaneously improving exposure latitude, depth-of-focus and ultimate resolution. In this work, we briefly discuss a next-generation resist model for the prediction of statistical resist responses such as line-edge roughness, line-width roughness and CD variability, as well as base lithographic responses such as exposure latitude. The model's parameterized fit to experimental data from a state-of-the art polymer-bound PAG resist irradiated at ArF and EUV will be shown. The probabilistic computation of acid generation at ArF and EUV will be discussed. The factors influencing the hypothesized primary cause of resist roughness, acid shot noise, are discussed.

  3. [VR and AR Applications in Medical Practice and Education]. (United States)

    Hsieh, Min-Chai; Lin, Yu-Hsuan


    As technology advances, mobile devices have gradually turned into wearable devices. Furthermore, virtual reality (VR), augmented reality (AR), and mixed reality (MR) are being increasingly applied in medical fields such as medical education and training, surgical simulation, neurological rehabilitation, psychotherapy, and telemedicine. Research results demonstrate the ability of VR, AR, and MR to ameliorate the inconveniences that are often associated with traditional medical care, reduce incidents of medical malpractice caused by unskilled operations, and reduce the cost of medical education and training. What is more, the application of these technologies has enhanced the effectiveness of medical education and training, raised the level of diagnosis and treatment, improved the doctor-patient relationship, and boosted the efficiency of medical execution. The present study introduces VR, AR, and MR applications in medical practice and education with the aim of helping health professionals better understand the applications and use these technologies to improve the quality of medical care.

  4. Fold dating: A new Ar/Ar illite dating application to constrain the age of deformation in shallow crustal rocks (United States)

    Fitz-Diaz, Elisa; van der Pluijm, Ben


    We propose a deformation dating method that combines XRD quantification and Ar chronology of submicroscopic illite to determine the absolute ages of folds that contain clay-bearing layers. Two folds in the frontal segment of the Mexican Fold-Thrust Belt (MFTB), which was deformed from Late Cretaceous to Eocene, are used to illustrate the method and its future potential. Variations in mineral composition, illite-polytype, crystallite-size (CS) and Ar total gas ages were analyzed in the limbs and hinge of two mesoscopic folds. This analysis examines potential effects of strain variation on illitization and the Ar isotopic system along folded layers, versus possible regional thermal overprints. The Ar total-gas ages for 9 samples in Fold 1 vary between 48.4 and 43.9 Ma. The % of 2M1 (detrital) illite vs. Ar total-gas ages tightly constrains the age of folding at 43.5 ± 0.3 Ma. Nine ages from three samples in Fold 2 range from 76.2 to 62.7 Ma, which results in a folding age of 63.9 ± 2.2 Ma. Both ages are in excellent agreement with more broadly constrained stratigraphic timing. The method offers a novel approach to radiometric dating of clay-bearing folds formed at very low-grade metamorphic conditions, and has the potential to constrain dates and rates of regional and local deformation along and across foreland orogenic belts.

  5. How reliable are {sup 39}Ar groundwater ages?

    Energy Technology Data Exchange (ETDEWEB)

    Purtschert, R.; Loosli, H.H.; Corcho Alvarado, J.A. [Bern Univ., Inst. fuer Physik, Climate and Environmental Physics Div. (Switzerland)


    Increasing over-exploitation and contamination of shallow groundwaters increase also the demand for deeper and older groundwater resources. The potential and need for dating tools for the age range between young waters dated by {sup 3}He/{sup 3}H, SF{sub 6}, {sup 85}Kr, and CFC's and older waters dated e.g. by {sup 14}C, {sup 4}He, {sup 36}Cl and {sup 81}Kr is therefore undisputed. Due to a half live of 269 years {sup 39}Ar is a perfect candidate to fill this gap. Based on data from several groundwater systems, we will discuss the suitability and limitation of {sup 39}Ar in groundwater research. Underground production was always mentioned as the main problem of {sup 39}Ar dating. Our experience show, that in most cases this possibility can either be excluded or is of minor importance. For a few examples, however, we have to conclude that subsurface produced {sup 39}Ar activities does not allow radioactive dating. Dating is however only one aspect of the interpretation of {sup 39}Ar results: age- and mixing studies are always connected. Furthermore, time and space related measuring series give information about shifts of the age structures of the groundwater. Underground produced {sup 39}Ar can also provide valuable information because it's a transient 'fingerprint' of the percolated rock formations. A systematic summary is given about important practical questions and the possibilities to find answers from multi-tracer studies. (authors)

  6. Axenfeld-Rieger syndrome (ARS): A review and case report.

    LENUS (Irish Health Repository)

    Waldron, Jennie M


    Axenfeld-Rieger syndrome (ARS) is a rare, autosomal dominant condition characterized by ocular, craniofacial, dental, and periumbilical abnormalities. Relatively little information exists on this syndrome within the dental literature despite the fact that midface hypoplasia and maxillary hypodontia are classical presenting features of this syndrome. This is a case report of a 7-year-old Caucasian female with ARS who presented with significant ocular and dental anomalies. She was also found to have osteopenia. Her dental condition is described, her immediate treatment is shown, and her long-term treatment needs are discussed.

  7. Arándano rojo I (Vaccinium macrocarpon Ait.)


    Garrido Conejero, M. Victoria; Pérez-Urria Carril, Elena


    El arándano rojo o arándano rojo americano (Vaccinium macrocarpon Ait.) es una fruta muy consumida y apreciada que ha ganado popularidad con los años debido en parte a su contenido en compuestos beneficiosos para la salud humana. En el trabajo se consideran aspectos botánicos, composición nutricional y contenido en compuestos fitoquímicos, datos históricos y culturales e información sobre el cultivo de esta especie vegetal y sus variedades. También se considera su importancia económica y algu...

  8. Interatomic scattering in energy dependent photoelectron spectra of Ar clusters

    Energy Technology Data Exchange (ETDEWEB)

    Patanen, M.; Benkoula, S.; Nicolas, C.; Goel, A. [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex (France); Antonsson, E. [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex (France); Physikalische und Theoretische Chemie Institut für Chemie und Biochemie, Fachbereich Biologie, Chemie, Pharmazie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin (Germany); Neville, J. J. [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex (France); Department of Chemistry, University of New Brunswick, Fredericton, New Brunswick E3B 6E2 (Canada); Miron, C., E-mail: [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, 91192 Gif-sur-Yvette Cedex (France); Extreme Light Infrastructure - Nuclear Physics (ELI-NP), ‘Horia Hulubei’ National Institute for Physics and Nuclear Engineering, 30 Reactorului Street, RO-077125 Măgurele, Jud. Ilfov (Romania)


    Soft X-ray photoelectron spectra of Ar 2p levels of atomic argon and argon clusters are recorded over an extended range of photon energies. The Ar 2p intensity ratios between atomic argon and clusters’ surface and bulk components reveal oscillations similar to photoelectron extended X-ray absorption fine structure signal (PEXAFS). We demonstrate here that this technique allows us to analyze separately the PEXAFS signals from surface and bulk sites of free-standing, neutral clusters, revealing a bond contraction at the surface.

  9. Silver nano particle formation on Ar plasma - treated cinnamyl alcohol

    Energy Technology Data Exchange (ETDEWEB)

    Dahle, S. [Institut fuer Physik und Physikalische Technologien, Technische Universitaet Clausthal, Leibnizstrasse 4, 38678 Clausthal-Zellerfeld (Germany); Hochschule fuer Angewandte Wissenschaft und Kunst, Fakultaet fuer Naturwissenschaften und Technik, Von-Ossietzky-Strasse 99, 37085 Goettingen (Germany); Marschewski, M. [Institut fuer Physik und Physikalische Technologien, Technische Universitaet Clausthal, Leibnizstrasse 4, 38678 Clausthal-Zellerfeld (Germany); Wegewitz, L.; Maus-Friedrichs, W. [Institut fuer Physik und Physikalische Technologien, Technische Universitaet Clausthal, Leibnizstrasse 4, 38678 Clausthal-Zellerfeld (Germany); Clausthaler Zentrum fuer Materialtechnik, Technische Universitaet Clausthal, Leibnizstrasse 4, 38678 Clausthal-Zellerfeld (Germany); Vioel, W. [Hochschule fuer Angewandte Wissenschaft und Kunst, Fakultaet fuer Naturwissenschaften und Technik, Von-Ossietzky-Strasse 99, 37085 Goettingen (Germany)


    Metastable induced electron spectroscopy, ultraviolet photoelectron spectroscopy, X-ray photoelectron spectroscopy, and atomic force microscopy are employed to study the adsorption of silver on cinnamyl alcohol films prepared on Au(111) substrates by thermal evaporation. Additionally, the impact of an Ar atmosphere dielectric barrier discharge plasma applied to the cinnamyl alcohol film preliminary to the Ag adsorption is investigated. In both cases silver nano particles with an average diameter of 9 nm are formed. These particles do not interact chemically with the underlying cinnamyl alcohol film. We do not find any influence of the preliminary Ar plasma-treatment on the adsorption behavior at all.

  10. 40Ar/39Ar geochronology at the Instituto de Geociências, USP: instrumentation, analytical procedures, and calibration

    Directory of Open Access Journals (Sweden)



    Full Text Available Laser heating 40Ar/39Ar geochronology provides high analytical precision and accuracy, mum-scale spatial resolution, and statistically significant data sets for the study of geological and planetary processes. A newly commissioned 40Ar/39Ar laboratory at CPGeo/USP, São Paulo, Brazil, equips the Brazilian scientific community with a new powerful tool applicable to the study of geological and cosmochemical processes. Detailed information about laboratory layout, environmental conditions, and instrumentation provides the necessary parameters for the evaluation of the CPGeo/USP 40Ar/39Ar suitability to a diverse range of applications. Details about analytical procedures, including mineral separation, irradiation at the IPEN/CNEN reactor at USP, and mass spectrometric analysis enable potential researchers to design the necessary sampling and sample preparation program suitable to the objectives of their study. Finally, the results of calibration tests using Ca and K salts and glasses, international mineral standards, and in-house mineral standards show that the accuracy and precision obtained at the 40Ar/39Ar laboratory at CPGeo/USP are comparable to results obtained in the most respected laboratories internationally. The extensive calibration and standardization procedures undertaken ensure that the results of analytical studies carried out in our laboratories will gain immediate international credibility, enabling Brazilian students and scientists to conduct forefront research in earth and planetary sciences.A geocronologia de 40Ar/39Ar por aquecimento a laser permite alta precisão e acurácia analítica, tem resolução espacial em escala micrométrica, e fornece um número de dados estatisticamente significantes para o estudo de processos geológicos e planetários. Um recém construído laboratório de 40Ar/39Ar no CPGeo/USP, São Paulo, Brazil, mune a sociedade científica brasileira com uma técnica eficaz aplicável aos estudos geol

  11. Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides. (United States)

    Watson, Donald A; Su, Mingjuan; Teverovskiy, Georgiy; Zhang, Yong; García-Fortanet, Jorge; Kinzel, Tom; Buchwald, Stephen L


    Despite increasing pharmaceutical importance, fluorinated aromatic organic molecules remain difficult to synthesize. Present methods require either harsh reaction conditions or highly specialized reagents, making the preparation of complex fluoroarenes challenging. Thus, the development of general methods for their preparation that overcome the limitations of those techniques currently in use is of great interest. We have prepared [LPd(II)Ar(F)] complexes, where L is a biaryl monophosphine ligand and Ar is an aryl group, and identified conditions under which reductive elimination occurs to form an Ar-F bond. On the basis of these results, we have developed a catalytic process that converts aryl bromides and aryl triflates into the corresponding fluorinated arenes by using simple fluoride salts. We expect this method to allow the introduction of fluorine atoms into advanced, highly functionalized intermediates.

  12. Thermal History of the Felsite Unit, Geysers Geothermal Field, From Thermal Modeling of 40Ar/39Ar Incremental Heating Data

    Energy Technology Data Exchange (ETDEWEB)

    T. M. Harrison (U of California); G. B. Dalrymple (Oregon State U); J. B. Hulen (U of Utah); M. A. Lanphere; M. Grove; O. M. Lovera


    An Ar-40/Ar-39 and U-Pb study was performed of the Geysers plutonic complex of the Geysers Geothermal Field in California. Sixty-nine ion microprobe spot analyses of zircons from four granite samples from the plutonic complex that underlies the Geysers geothermal field yielded Pb-207/Pb-206 vs. U-238/Pb-206 concordia ages ranging from 1.13 {+-} 0.04 Ma to 1.25 {+-} 0.04 Ma. The U-Pb ages coincide closely with Ar-40/Ar-39 age spectrum plateau and ''terminal'' ages from coexisting K-feldspars and with the eruption ages of overlying volcanic rocks. The data indicate that the granite crystallized at 1.18 Ma and had cooled below 350 C by {approximately}0.9-1.0 Ma. Interpretation of the feldspar Ar-40/Ar-39 age data using multi-diffusion domain theory indicates that post-emplacement rapid cooling was succeeded either by slower cooling from 350-300 C between 1.0 and 0.4 Ma or transitory reheating to 300-350 C at about 0.4-0.6 Ma. Heat flow calculations constrained with K-feldspar thermal histories and the pre sent elevated regional heal flow anomaly demonstrate that appreciable heat input from sources external to the known Geysers plutonic complex is required to maintain the geothermal system. This requirement is satisfied by either a large, underlying, convecting magma chamber (now solidified) emplaced at 1.2 Ma or episodic intrusion of smaller bodies from 1.2-0.6 Ma.

  13. New chronometers for the metamorphism of ophiolitic rocks: 40Ar/39Ar neptunite and 232Th/208Pb joaquinite (United States)

    Borneman, N.; Hodges, K. V.; Van Soest, M. C.


    Both primary magmatism and metamorphism of ophiolite sequences are difficult to date, due in large part to the fact that the majority of lithologies present tend to contain very low concentrations of radioactive elements. As a result, researchers are often forced to process large amounts of material to search for accessory phases like zircons in gabbro, or to employ geochronometers that often yield multiply interpretable results (e.g., 40Ar/39Ar glaucophane or phengite), or to rely on indirect evidence for inferring ages. Here, we introduce two new options for chronometery of metamorphosed ophiolites: 40Ar/39Ar neptunite and 232Th/208Pb joaquinite. The best known locality for these rare minerals is the New Idria serpentinite diapir, found within the southern Diablo Range of the Coast Range Province of California. Here, both the joaquinite and neptunite chronometers record indistinguishable dates that we interpret to be the crystallization age of the phases during diapir ascent, based on the demonstrated low temperature history of the diapir as whole and the agreement of dates from chromonometers that almost certainly have different closure temperatures. This age is generally inferred to be coincident with the timing of the passage of the Mendocino Triple Junction and associated initiation of the San Andreas fault in this area. We propose that the mean40Ar/39Ar neptunite plateau date of 12.375 ± 0.082 Ma and corroborating 232Th/208Pb joaquinite date (12.08 ± 0.59 Ma) may represent a high-precision constraint on the timing of this event. We also report a second application of these chronometers to samples from the Yarlung suture, which formed at the time of initial India-Eurasia collision in southern Tibet. Here, both chronometers record indistinguishable dates of ca. 52 Ma, which we also interpret as the crystallization age. This age is consistent with most previously published estimates for the timing of the India-Eurasia collision.

  14. Shock tube study of the reaction H plus O2 plus Ar yields HO2 plus Ar (United States)

    Jachimowski, C. J.; Houghton, W. M.


    Rate coefficient data for the recombination reaction H + 02 + Ar yields H02 + Ar have been determined from studies of lean hydrogen-oxygen mixtures behind incident shock waves over the temperature range of 948 to 1125 K. Hydroxyl radical concentration profiles were measured by ultraviolet absorption spectroscopy, and rate data were obtained through analysis of induction time and exponential growth parameter data. Analysis of the data yielded a rate coefficient which was generally lower than most of the more recent values obtained from shock tube studies. The effect of boundary layer formation on the conditions behind the shock was also examined and found to be negligible.

  15. Provenance studies from 40Ar/ 39Ar dating of mineral inclusions in diamonds: Methodological tests on the Orapa kimberlite, Botswana (United States)

    Phillips, D.; Harris, J. W.


    Previous studies indicate that clinopyroxene inclusions extracted from their host diamonds give 40Ar/ 39Ar ages approaching the time of source kimberlite eruption. This behaviour is attributed to diffusion of argon to the diamond/inclusion interface region during mantle residence, with subsequent loss of this component on cleaving of the diamond to release the inclusion(s). In this study, we investigate the potential of the 40Ar/ 39Ar inclusion dating method as a niche provenance tool. As diamondiferous kimberlites are uncommon igneous rocks, largely restricted to Archaean cratons and have limited age ranges, provenance studies of detrital diamond occurrences should provide unique information on craton erosional histories, palaeo-drainage evolution and related basin development. As a methodological test, 40Ar/ 39Ar step-heating and in vacuo crushing experiments were conducted on 50 eclogitic clinopyroxene inclusions extracted from diamonds from the ˜ 93 Ma Orapa kimberlite in Botswana. Low temperature steps and crushing experiments produced anomalously old ages (up to 2.98 ± 0.10 Ga), consistent with partial retention of pre-eruption (inherited) argon in sub-micron(?) defect sites. High temperature (fusion) steps yielded significantly younger ages, although only 35% are within error of the time of Orapa kimberlite eruption. However, 77% of results are within 50 Ma, and 92% within 100 Ma, of the Orapa eruption age. These results mandate that individual fusion ages be treated as maximum estimates of source kimberlite eruption ages, with analyses of several (> 6) inclusions required to date single-age detrital populations. For multi-source diamond deposits, only the youngest detrital population, or populations separated by > 100 Ma, will be resolvable. Despite these limitations, we conclude that the 40Ar/ 39Ar inclusion dating method is still capable of resolving key provenance questions, such as the source of detrital diamond deposits in southern Africa, where

  16. A Carbon Cycle Science Update Since IPCC AR-4

    NARCIS (Netherlands)

    Dolman, A.J.; Werf, van der G.R.; Molen, van der M.K.; Ganssen, G.; Erisman, J.W.; Strengers, B.


    We review important advances in our understanding of the global carbon cycle since the publication of the IPCC AR4. We conclude that: the anthropogenic emissions of CO2 due to fossil fuel burning have increased up through 2008 at a rate near to the high end of the IPCC emission scenarios; there are

  17. Ars Fennica - isikliku ja poliitilise vahel / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-


    2008. aasta Ars Fennica kunstiauhinna kandidaatide tööde näitus Kumu Kunstimuuseumis kuni 26. aprillini. Läti kunstniku Katrina Neiburga, soomlaste Seppo Renvalli, Maria Dunckeri ja Tea Mäkipää ning Mark Raidpere näitusel eksponeeritud töödest

  18. Data management and database structure at the ARS Culture Collection (United States)

    The organization and management of collection data for the 96,000 strains held in the ARS Culture Collection has been an ongoing process. Originally, the records for the four separate collections were maintained by individual curators in notebooks and/or card files and subsequently on the National C...

  19. Multi-particle emission in the decay of $^{31}$Ar

    CERN Document Server

    Koldste, G T; Borge, M.J.G.; Briz, J.A.; Carmona-Gallardo, M.; Fraile, L.M.; Fynbo, H.O.U.; Giovinazzo, J.; Grann, B.D.; Johansen, J.G.; Jokinen, A.; Jonson, B.; Kurturkian-Nieto, T.; Kusk, J.H.; Nilsson, T.; Perea, A.; Pesudo, V.; Picado, E.; Riisager, K.; Saastamoinen, A.; Tengblad, O.; Thomas, J.C.; Van de Walle, J.


    A multi-hit capacity setup was used to study the decay of the dripline nucleus 31Ar, produced at the ISOLDE facility at CERN. A spectroscopic analysis of the beta-delayed three-proton decay of 31Ar is presented for the first time together with a quantitative analysis of the beta-delayed two-proton-gamma-decay. A new method for determination of the spin of low-lying levels in the beta-proton-daughter 30S using proton-proton angular correlations is presented and used for the level at 5.2 MeV, which is found to be either a 3+ or 4+ level, with the data pointing towards the 3+. The half-life of 31Ar is found to be 15.1(3) ms. An improved analysis of the Fermi beta-strength gives a total measured branching for the beta-3p-decay of 3.60(44) %, which is lower than the theoretical value found to be 4.24(43) %. Finally the strongest gamma-transitions in the decay of 33Ar are shown including a line at 4734(3) keV associated to the decay of the IAS, which has not previously been identified.

  20. Pulsed electric field (PEF)research at USDA, ARS, ERRC (United States)

    This article summarizes the effects of pulsed electric fields on the microbiological safety and quality aspects of various liquid food matrices, obtained at USDA, ARS, Eastern Regional Research Center under CRIS Project No. 1935-41420-013-00D, Processing Intervention Technologies for Enhancing the S...

  1. Immune epitope database analysis resource (IEDB-AR)

    DEFF Research Database (Denmark)

    Zhang, Qing; Wang, Peng; Kim, Yohan


    We present a new release of the immune epitope database analysis resource (IEDB-AR,, a repository of web-based tools for the prediction and analysis of immune epitopes. New functionalities have been added to most of the previously implemented tools, and a total of ...

  2. ARS labs update to California Cotton Ginners and Growers (United States)

    There are four USDA-ARS labs involved in cotton harvesting, processing & fiber quality research; The Southwestern Cotton Ginning Research Laboratory (Mesilla Park, NM); The Cotton Production and Processing Unit (Lubbock, TX); The Cotton Ginning Research Unit (Stoneville, MS); and The Cotton Structur...

  3. Selective AR Modulators that Distinguish Proliferative from Differentiative Gene Promoters (United States)


    deregulation of AR activity and androgen synthesis in prostate cancer. Trends in endocrinology and metabolism: TEM , 2010. 21(5): p. 315-24. 2. Sahu, B...23): p. 5624-9. 11. Rhee, H.S. and B.F. Pugh, Genome-wide structure and organization of eukaryotic pre-initiation complexes. Nature, 2012. 483(7389): p


    African Journals Online (AJOL)

    The Ndu Volcanic Ridge occupies the central position amongst the continental sector volcanoes of the Cameroon Volcanic Line. K-Ar age determination coupled with field observations show that there were three episodes of volcanic manifestation: 31-28 Ma; 23-21 Ma and <1 Ma. Basaltic magmas were erupted during the ...

  5. The ARS Culture Collection and Developments in Biotechnology (United States)

    The ARS Culture Collection (NRRL) has played a prominent role in the development of biotechnology since its founding in 1940 when the Northern Regional Research Laboratory opened. Early discoveries included selection of production strains for penicillin, dextran blood extender, xanthan gum and the v...

  6. Big data computing: Building a vision for ARS information management (United States)

    Improvements are needed within the ARS to increase scientific capacity and keep pace with new developments in computer technologies that support data acquisition and analysis. Enhancements in computing power and IT infrastructure are needed to provide scientists better access to high performance com...

  7. Loopedia, a Database for Loop Integrals arXiv

    CERN Document Server

    Bogner, C.; Hahn, T.; Heinrich, G.; Jones, S.P.; Kerner, M.; von Manteuffel, A.; Michel, M.; Panzer, E.; Papara, V.

    Loopedia is a new database at for information on Feynman integrals, intended to provide both bibliographic information as well as results made available by the community. Its bibliometry is complementary to that of SPIRES or arXiv in the sense that it admits searching for integrals by graph-theoretical objects, e.g. its topology.

  8. Mälestusi "Ars Fennica'st" / Eha Komissarov

    Index Scriptorium Estoniae

    Komissarov, Eha, 1947-


    Ars Fennica 2008. aasta nominentide Tea Mäkipää, Seppo Renvalli, Maria Dunckeri, Katrīna Neiburga (Läti) ja Mark Raidpere näitus Kumu Kunstimuuseumis 26. aprillini. Preemiaga pärjati Mark Raidpere ekspositsioon

  9. Interacting with Visual Poems through AR-Based Digital Artwork (United States)

    Lin, Hao-Chiang Koong; Hsieh, Min-Chai; Liu, Eric Zhi-Feng; Chuang, Tsung-Yen


    In this study, an AR-based digital artwork called "Mind Log" was designed and evaluated. The augmented reality technique was employed to create digital artwork that would present interactive poems. A digital poem was generated via the interplay between a video film and a text-based poem. This artwork was created following a rigorous design flow,…

  10. Chromosomal context and replication properties of ARS plasmids in ...

    Indian Academy of Sciences (India)


    Nov 28, 2015 ... Saccharomyces cerevisiae ARS elements are small (~100 to 150 bp) in size ... variability in their activity as compared to S. cerevisiaeorigins and majority of them ..... was determined by growing three transformants on selective medium, plating equal number of cells onto selective and non selective plates.

  11. Preparation and characterization of a $^{39}Ar$ sample and study of the $^{39}Ar(n_{th},\\alpha)^{36}S$ reaction

    CERN Document Server

    Goeminne, G; Geltenbort, P; Johansson, L; Köster, U; Pommé, S; Wagemans, C; Wagemans, J


    The $^{39}$Ar(n$_{\\rm th}$,$\\alpha$)$^{36}$S reaction has been studied for the first time. A sample containing $2.85 \\times 10^{14}$ $^{39}$Ar atoms, was produced at the ISOLDE facility at CERN. The number of $^{39}$Ar atoms in the layer was determined by measuring the $^{39}$Ar $\\beta$-activity using a primary standardization method. Subsequently, the sample was irradiated with thermal neutrons at the High Flux Reactor of the ILL. An upper limit of 0.29~b was obtained for the $^{39}$Ar(n$_{\\rm th}$,$\\alpha$)$^{36}$S reaction cross-section.

  12. Preparation and characterization of a $^{39}Ar$ sample and study of the $^{39}Ar(n_{th},\\alpha)^{36}S$ reaction


    Goeminne, G; Denecke, B; Geltenbort, P; Johansson, L; Köster, U; Pommé, S; Wagemans, C; Wagemans, J


    The $^{39}$Ar(n$_{\\rm th}$,$\\alpha$)$^{36}$S reaction has been studied for the first time. A sample containing $2.85 \\times 10^{14}$ $^{39}$Ar atoms, was produced at the ISOLDE facility at CERN. The number of $^{39}$Ar atoms in the layer was determined by measuring the $^{39}$Ar $\\beta$-activity using a primary standardization method. Subsequently, the sample was irradiated with thermal neutrons at the High Flux Reactor of the ILL. An upper limit of 0.29~b was obtained for the $^{39}$Ar(n$_{\\...

  13. Behaviour of AR glass fibre for building structural applications

    Directory of Open Access Journals (Sweden)

    Miravete, A.


    Full Text Available The AR glass reinforcement fibres were designed to resist the alkalis from the concrete. This is the main reason for its utilisation as a short-fibre-reinforcement of mortar and concrete for the last decades. Originally, the AR glass fibre sizing was not compatible with synthetic resins, so that this type of reinforcement was applied exclusively to mortar and concrete matrices. Recently, due to the developments of sizing, which are compatible with synthetic resins, the AR- glass fibres may be used as reinforcement of organic matrix composite materials, broadening the range of structural applications. The mechanical properties of AR glass fibre and organic matrix composite materials will be studied in this paper. First, the behaviour of this material under stress corrosion will be analysed. Their mass loss will be compared to E, C, and boron free glass fibres. Second, an experimental study dealing with 3P test bending and short beam ofAR glass fibre/polyester will de described with the goal of obtaining their Young modulus and tensile and interlaminar shear strengths. Finally, these experimental results will be compared to E glass fibre/polyester and several conclusions about their structural applications will be drawn.

    El vidrio AR y su presentación en forma de fibras de refuerzo, fue diseñado para ser inerte a los álcalis de los cementos. Por este motivo se viene utilizando desde hace varias décadas como refuerzo de morteros y hormigones en forma de fibra corta. El ensimaje que estas fibras de vidrio de refuerzo A R presentaba en su origen no era compatible con resinas de tipo sintéticas, por lo que el refuerzo era exclusivo para cementos y hormigones fuera cual fuera la aplicación, formato o proceso productivo. Recientemente, gracias al desarrollo específico de ensimajes especiales acordes a las fibras de vidrio AR ha aparecido la misma tipología de vidrio AR como refuerzo en forma de fibra continua compatible con resinas sint

  14. The AR Sandbox: Augmented Reality in Geoscience Education (United States)

    Kreylos, O.; Kellogg, L. H.; Reed, S.; Hsi, S.; Yikilmaz, M. B.; Schladow, G.; Segale, H.; Chan, L.


    The AR Sandbox is a combination of a physical box full of sand, a 3D (depth) camera such as a Microsoft Kinect, a data projector, and a computer running open-source software, creating a responsive and interactive system to teach geoscience concepts in formal or informal contexts. As one or more users shape the sand surface to create planes, hills, or valleys, the 3D camera scans the surface in real-time, the software creates a dynamic topographic map including elevation color maps and contour lines, and the projector projects that map back onto the sand surface such that real and projected features match exactly. In addition, users can add virtual water to the sandbox, which realistically flows over the real surface driven by a real-time fluid flow simulation. The AR Sandbox can teach basic geographic and hydrologic skills and concepts such as reading topographic maps, interpreting contour lines, formation of watersheds, flooding, or surface wave propagation in a hands-on and explorative manner. AR Sandbox installations in more than 150 institutions have shown high audience engagement and long dwell times of often 20 minutes and more. In a more formal context, the AR Sandbox can be used in field trip preparation, and can teach advanced geoscience skills such as extrapolating 3D sub-surface shapes from surface expression, via advanced software features such as the ability to load digital models of real landscapes and guiding users towards recreating them in the sandbox. Blueprints, installation instructions, and the open-source AR Sandbox software package are available at .

  15. Precision angle-resolved autoionization resonances in Ar and Ne

    Energy Technology Data Exchange (ETDEWEB)

    Berrah, N.; Langer, B.; Gorczyca, T.W. [Western Michigan Univ., Kalamazoo, MI (United States)] [and others


    Theoretical work has shown that the electron angular distribution and the shape of the autoionization resonances are crucial to the understanding of certain types of electron-electron correlation. Autoionization resonances in Ne (Ar) result from the decay of the excited discrete state Ne{sup *} 2s2p{sup 6} np (Ar{sup *} 3s3p{sup 6} np) into the continuum state Ne{sup +} 2s{sup 2}2p{sup 5} + e{sup {minus}} (ks,kd) (Ar{sup +} 3s{sup 2}3p{sup 5} + e{sup {minus}} (ks,kd)). Since the continuum can also be reached by direct photoionization, both paths add coherently, giving rise to interferences that produce the characteristic Beutler-Fano line shape. In this work, the authors report on quantitative angle-resolved electron spectrometry studies of (a) the Ne 2s{sup 2}2p{sup 6} {r_arrow} 2s2p{sup 6} np (n=3-5) autoionizing resonances and the 2s{sup 2}2p{sup 6} {r_arrow} 2p{sup 4}3s3p doubly excited resonance, (b) the Ar 3s{sup 2}3p{sup 6} {r_arrow} 3s3p{sup 6} np (n=4-9) autoionization resonances and extended R-matrix calculations of the angular-distribution parameters for both Ne and Ar measurements. Their results are compared with previous theoretical work by Taylor.

  16. Mid-Cenozoic Caetano Tuff, Nevada: Tectonic and correlation implications from paleomagnetic data and sanidine 40Ar/39Ar dating (United States)

    MacDonald, W. D.; Deino, A. L.; Palmer, H. C.


    Paleomagnetic results at more than 50 sites in strata mapped as Caetano Tuff in central Nevada reveal characteristic magnetizations with reverse polarity, up to the SE. The site-mean Caetano Tuff paleomagnetic pole (168.7°E, 68.6°N, A95=4.4°, n=44), differs from a reference pole for North America (BC02) by 15±6°. This implies a regional counterclockwise rotation of the sampling region of 9° to 21° relative to cratonic North America. The inferred rotation is estimated to have occurred in the interval 34 to 10 Ma, associated with regional Basin and Range rifting. Twelve new 40Ar/39Ar ages from Caetano ash-flow tuffs and associated rocks, combined with previously published 40Ar/39Ar ages, indicate an age of about 33.76 Ma for the Caetano Tuff. Jointly, the age and polarity information indicate that the eruptions of the Caetano Tuff occurred near the younger limit of polarity chron C13r. Relative to the International Commission of Stratigraphy timescale 2008, the Caetano Tuff is earliest Oligocene. However, relative to recent astronomically tuned geomagnetic polarity timescale chron boundaries, it is latest Eocene.

  17. Geochemistry and 40Ar/39Ar age of Early Carboniferous dolerite sills in the southern Baltic Sea

    Directory of Open Access Journals (Sweden)

    Gediminas Motuza


    Full Text Available The Early Carboniferous magmatic event in the southern Baltic Sea is manifested by dolerite intrusions. The presumable area in which the dolerite intrusions occur ranges from 30 to 60 km in east–west direction, and is about 100 km in north–south direction. The dolerites were sampled in well D1-1 and investigated by applying chemical analysis and 40Ar/39Ar step-heating dating. Dolerites are classified as alkali and sodic, characterized by high TiO2 (3.92, 3.99 wt% and P2O5 (1.67, 1.77 wt% and low MgO (4.89, 4.91 wt% concentrations, enriched in light rare earth elements, originated from an enriched mantle magma source and emplaced in a continental rift tectonic setting. The 351 ± 11 Ma 40Ar/39Ar plateau age for groundmass plagioclase indicates a considerable age gap with the 310–250 Ma magmatism in southern Scandinavia and northern Germany. The magmatic rocks in the Baltic Sedimentary Basin are coeval with alkaline intrusions of NE Poland. Both magmatic provinces lie in the northwestward prolongation of the Pripyat–Dnieper–Donetsk Rift (370–359 Ma and may constitute a later phase of magmatic activity of this propagating rift system.

  18. Development of a Low-Level Ar-37 Calibration Standard

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Richard M.; Aalseth, Craig E.; Bowyer, Ted W.; Day, Anthony R.; Fuller, Erin S.; Haas, Derek A.; Hayes, James C.; Hoppe, Eric W.; Humble, Paul H.; Keillor, Martin E.; LaFerriere, Brian D.; Mace, Emily K.; McIntyre, Justin I.; Miley, Harry S.; Myers, Allan W.; Orrell, John L.; Overman, Cory T.; Panisko, Mark E.; Seifert, Allen


    Argon-37 is an important environmental signature of an underground nuclear explosion. Producing and quantifying low-level 37Ar standards is an important step in the development of sensitive field measurement instruments for use during an On-Site Inspection, a key provision of the Comprehensive Nuclear-Test-Ban Treaty. This paper describes progress at Pacific Northwest National Laboratory (PNNL) in the development of a process to generate and quantify low-level 37Ar standard material, which can then be used to calibrate sensitive field systems at activities consistent with soil background levels. The 37Ar used for our work was generated using a laboratory-scale, high-energy neutron source to irradiate powdered samples of calcium carbonate. Small aliquots of 37Ar were then extracted from the head space of the irradiated samples. The specific activity of the head space samples, mixed with P10 (90% stable argon:10% methane by mole fraction) count gas, is then derived using the accepted Length-Compensated Internal-Source Proportional Counting method. Due to the low activity of the samples, a set of three Ultra-Low Background Proportional-Counters designed and fabricated at PNNL from radio-pure electroformed copper was used to make the measurements in PNNL’s shallow underground counting laboratory. Very low background levels (<10 counts/day) have been observed in the spectral region near the 37Ar emission feature at 2.8 keV. Two separate samples from the same irradiation were measured. The first sample was counted for 12 days beginning 28 days after irradiation, the second sample was counted for 24 days beginning 70 days after irradiation (the half-life of 37Ar is 35.0 days). Both sets of measurements were analyzed and yielded very similar results for the starting activity (~0.1 Bq) and activity concentration (0.15 mBq/ccSTP argon) after P10 count gas was added. A detailed uncertainty model was developed based on the ISO Guide to the Expression of Uncertainty in

  19. Deciphering the Paleoproterozoic cooling history of the northeastern Trans-Hudson Orogen, Baffin Island (Canada), using 40Ar/39Ar step-heating and UV laser thermochronology (United States)

    Skipton, D. R.; Schneider, D. A.; Kellett, D. A.; Joyce, N. L.


    The previously unstudied cooling and exhumation history of mid-crustal rocks exposed on southeastern Baffin Island (Canada) provides new insights into the post-orogenic evolution of the Paleoproterozoic Trans-Hudson Orogen (THO). New 40Ar/39Ar step-heat analyses of biotite, muscovite and phlogopite and core-to-rim intra-grain 40Ar/39Ar analyses of muscovite have a range of apparent ages compatible with slow regional cooling following peak metamorphism. Twenty-nine amphibolite- to granulite-facies rocks were dated using the 40Ar/39Ar step-heating laser (CO2) method. 40Ar/39Ar spot analyses were performed across muscovite grains from three samples using an ultraviolet (UV) laser to investigate intra-grain 40Ar/39Ar age variations. Step-heating apparent ages range from ca. 1788-1622 Ma for biotite, 1720-1630 Ma for phlogopite and 1729-1657 Ma for muscovite. UV spot 40Ar/39Ar analyses in the three muscovite grains range from ca. 1661-1640 Ma, 1675-1645 Ma and 1680-1652 Ma, with core-to-rim apparent age gradients of 20-30 Myr. Previous studies resolved peak metamorphism in this region to between ca. 1860 and 1820 Ma and identified late- to post-THO zircon and monazite populations at ca. 1800-1750 Ma. Numerical diffusion models for Ar in muscovite were conducted to test different Proterozoic cooling and exhumation scenarios. Comparisons with our 40Ar/39Ar ages attest to cooling rates of 1-2 °C/Myr following peak metamorphism and 1.5-2.5 °C/Myr after ca. 1740 Ma. Anomalously old apparent 40Ar/39Ar ages, in cases equivalent to U-Pb zircon rim and monazite ages, likely result from incorporation of excess Ar. The results suggest that mid-crustal rocks on southeastern Baffin Island remained hotter than 420-450 °C for 150-200 Myr after peak metamorphism, with subsequent slow cooling and denudation rates that are typical of Proterozoic orogens. The apparent absence of orogenic collapse implies that, despite high temperatures and estimated maximum crustal thicknesses

  20. Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents (United States)

    Zhang, Guanyi; Liu, Xichun; Li, Jianzhuo; Ledet, Elisa; Alvarez, Xavier; Qi, Yanfeng; Fu, Xueqi; Sartor, Oliver; Dong, Yan; Zhang, Haitao


    Docetaxel-based chemotherapy is established as a first-line treatment and standard of care for patients with metastatic castration-resistant prostate cancer. However, half of the patients do not respond to treatment and those do respond eventually become refractory. A better understanding of the resistance mechanisms to taxane chemotherapy is both urgent and clinical significant, as taxanes (docetaxel and cabazitaxel) are being used in various clinical settings. Sustained signaling through the androgen receptor (AR) has been established as a hallmark of CRPC. Recently, splicing variants of AR (AR-Vs) that lack the ligand-binding domain (LBD) have been identified. These variants are constitutively active and drive prostate cancer growth in a castration-resistant manner. In taxane-resistant cell lines, we found the expression of a major variant, AR-V7, was upregulated. Furthermore, ectopic expression of two clinically relevant AR-Vs (AR-V7 and ARV567es), but not the full-length AR (AR-FL), reduced the sensitivities to taxanes in LNCaP cells. Treatment with taxanes inhibited the transcriptional activity of AR-FL, but not those of AR-Vs. This could be explained, at least in part, due to the inability of taxanes to block the nuclear translocation of AR-Vs. Through a series of deletion constructs, the microtubule-binding activity was mapped to the LBD of AR. Finally, taxane-induced cytoplasm sequestration of AR-FL was alleviated when AR-Vs were present. These findings provide evidence that constitutively active AR-Vs maintain the AR signaling axis by evading the inhibitory effects of microtubule-targeting agents, suggesting that these AR-Vs play a role in resistance to taxane chemotherapy. PMID:26160840

  1. Synergic role of the two ars operons in arsenic tolerance in Pseudomonas putida KT2440. (United States)

    Fernández, Matilde; Udaondo, Zulema; Niqui, José-Luis; Duque, Estrella; Ramos, Juan-Luis


    The chromosome of Pseudomonas putida KT2440 carries two clusters of genes, denoted ars1 and ars2, that are annotated as putative arsenic resistance operons. In this work, we present evidence that both operons encode functional arsenic-response regulatory genes as well as arsenic extrusion systems that confer resistance to both arsenite [As(III)] and arsenate [As(V)]. Transcriptional fusions of P(ars1) and P(ars2) to lacZ revealed that expression of both operons was induced by arsenite and arsenate. We generated single mutants in ars1 and ars2, which showed lower resistance to arsenic than the wild-type strain. A double ars1/ars2 was found to be highly sensitive to arsenic. Minimum inhibitory concentrations (MICs) for single mutants decreased two- to fourfold with respect to the parental strain, while in the double mutant the MIC decreased 128-fold for arsenite and 32-fold for arsenate. Bioinformatic analysis revealed that the ars2 resistance operon is part of the core genome of P. putida, while the ars1 operon appears to only occur in the KT2440 strain, suggesting that ars1 was acquired by horizontal gene transfer. The presence of ars1 in KT2440 may explain why it exhibits higher resistance to arsenic than other P. putida strains, which bear only the ars2 operon.

  2. Evidence for pre-Cretaceous history and partial Neogene (19-9 Ma) reequilibration in the Karakorum (NW Himalayan Syntaxis) from 40Ar- 39Ar amphibole dating (United States)

    Rolland, Yann; Villa, Igor M.; Guillot, Stéphane; Mahéo, Gweltaz; Pêcher, Arnaud


    Amphiboles and a biotite from amphibolites and amphibolitic gneisses of the Karakorum Metamorphic Complex (KMC, NW Himalaya), were dated using the 40Ar/ 39Ar method. Isotope correlations were compared to electron-microprobe analyses. Both Al IV and Al VI contents of amphibole increase from the south near the Shyok Suture Zone to the Dassu-Askole Area in the north, with an increase in metamorphic grade (from anchizone to upper amphibolite facies). In the lower metamorphic zone, discordant age spectra were obtained. They are related to epidote-amphibolite overgrowth of amphibole rims on older (Precambrian to Mesozoic) magmatic cores. In the Shyok Suture Zone Ar/Ar ages of 38-62 Ma are contemporaneous with the emplacement of the Ladakh Batholith granodiorites, while middle Cretaceous magmatic Ar/Ar ages (˜ 120 Ma) are locally preserved in tschermakite relics. In the Southern Karakorum basement, a minimum Ar/Ar age of 651 Ma was preserved, while an age of 208.5±2 Ma was preserved in Panjal Trap-like diorites. At the margin of the domes zone, more recent metamorphism resulted in mineral growth at 20-5 Ma. In the domes zone, amphibole Ar/Ar ages of 17 Ma (Askole) and bimodal age spectra of 15-17 and 9-13 Ma (Dassu) extend towards the east the zone of Neogene amphibolite to granulite facies metamorphism known in the Nanga Parbat Syntaxis.

  3. A discussion regarding the contribution of intrapulmonary gas mixing to O2 isotope fractionation by respiration using experimental data for 36Ar and 40Ar. (United States)

    Luijendijk, S C M; Zegers, I H A; van der Grinten, C P M


    We determined the argon (Ar) isotope ratio in samples of expired alveolar gas gathered during Ar washout from residual gas relative to this ratio in samples of expired alveolar gas gathered just before the beginning of this washout in 13 young, healthy human subjects at rest. These data were determined for a limited number of breaths in early washout and were used to calculate the relative difference between the alveolar ventilations of (36)Ar and (40)Ar (Delta(rel)V (A)((36)Ar,(40)Ar)). Mean Delta(rel)V (A)((36)Ar,(40)Ar) amounted to 1.6 per thousand (S.D.=1.3 per thousand). This result was then used to discuss the contribution of intrapulmonary gas mixing by diffusion to oxygen isotope fractionation of alveolar gas by respiration. On the basis of our finding for Delta(rel)V (A)((36)Ar,(40)Ar) and further theoretical considerations we arrived at the conclusion that this contribution for subjects at rest is small (about 1 per thousand) and that this contribution is negative irrespective of the level of exercise.

  4. Ryoji Ikeda, Data Artist - Prix Ars Electronica Collide@CERN

    CERN Multimedia

    CERN. Geneva; Koek, Ariane; Heuer, Rolf; Ikeda, Ryoji; Mr. Horst, Hoertner


    at the CERN Globe of Science and Innovation, CERN. You are very warmly invited to the opening presentation of Data Artist, Ryoji Ikeda’s residency at CERN. Ryoji Ikeda, one of the world’s leading electronic composers and visual artists, is the new Prix Ars Electronica Collide@CERN award winner. Ryoji Ikeda and his science inspiration partner, Theoretical Physicist, Dr. Tom Melia will talk about their work in arts and science. They are at the beginning of their creative journey together at CERN. A little about Ryoji Ikeda – the new Prix Ars Electronica Collide@CERN artist in residence. Ryoji Ikeda focuses on the essential characteristics of sound itself and that of visuals as light by means of both mathematical precision and mathematical aesthetics. Ikeda has gained a reputation as one of the few international artists working convincingly across both visual ...

  5. A literary review of Arśas (haemorrhoids). (United States)

    Swamy, G K; Swamy, R K


    The disease Arśas (hemorrhoids), an ano-rectal disorder is as old as mankind. Suśrta farther of surgery described the Arśas under heading of 'Mahagadas' (eight major diseases). Due to inconsistency of human diet and social obligations, a large proportion of the population is suffering from hemorrhoids. As per Ayurveda, the etiological factors are broadly classified as Sămănya (Non-specific) and Viśĕsa (Specific). Viśĕsa again sub divided in to Sahaja and Janmottara. Suśrta classified this disease on the basis of clinical manifestations in to six types, where as Caraka and Văgbhata classified in to two according to discharging nature and causative factors respectively.

  6. Selective AR Modulators that Distinguish Proliferative from Differentiative Gene Promoters (United States)


    inhibitor into an oncoprotein following P21 loss (20). Moreover, in prostate cancer, P53 negatively regulates AR when over-expressed (21). These...Characterization of the androgen receptor in a benign prostate tissue-derived human prostate epithelial cell line: RC-165N/human telomerase reverse...dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Molecular endocrinology 13, 376 (Mar, 1999). 9

  7. AR-based Algorithms for Short Term Load Forecast


    Zuhairi Baharudin; Mohd. Azman Zakariya; Mohd. HarisMdKhir; Perumal Nallagownden; Muhammad Qamar Raza


    Short-term load forecast plays an important role in planning and operation of power systems. The accuracy of the forecast value is necessary for economically efficient operation and effective control of the plant. This study describes the methods of Autoregressive (AR) Burg’s and Modified Covariance (MCOV) in solving the short term load forecast. Both algorithms are tested with power load data from Malaysian grid and New South Wales, Australia. The forecast accuracy is assessed in terms of th...

  8. Secondary scintillation in Ar-CF$_4$ mixtures

    CERN Document Server

    Beschi, Andrea


    In order to build a optical time projection chamber that can be used as a tracking detector, it is necessary to study the scintillation proprieties of gases in order to optimize the light emission. A detailed study of the scintillation of Ar-CF$_4$ mixtures at different concentrations has been performed to study the light emission of the gas in a triple GEM detector.

  9. Enhanced sources of acoustic power surrounding AR11429


    Donea, Alina; Hanson, Christopher


    Multi-frequency power maps of the local acoustic oscillations show acoustic enhancements (\\acoustic-power halos") at high frequencies surrounding large active region. Computational seismic holography reveals a high-frequency \\acoustic-emission halo", or \\seismic glory" surrounding large active regions. In this study, we have applied computational seismic holography to map the seismic seismic source density surrounding AR 11429. Studies of HMI/SDO Doppler data, shows that the "acoustic halos" ...

  10. Modelling the ArH+ emission from the Crab nebula (United States)

    Priestley, F. D.; Barlow, M. J.; Viti, S.


    We have performed combined photoionization and photodissociation region (PDR) modelling of a Crab nebula filament subjected to the synchrotron radiation from the central pulsar wind nebula, and to a high flux of charged particles; a greatly enhanced cosmic-ray ionization rate over the standard interstellar value, ζ0, is required to account for the lack of detected [C I] emission in published Herschel SPIRE FTS observations of the Crab nebula. The observed line surface brightness ratios of the OH+ and ArH+ transitions seen in the SPIRE FTS frequency range can only be explained with both a high cosmic-ray ionization rate and a reduced ArH+ dissociative recombination rate compared to that used by previous authors, although consistent with experimental upper limits. We find that the ArH+/OH+ line strengths and the observed H2 vibration-rotation emission can be reproduced by model filaments with nH = 2 × 104 cm-3, ζ = 107ζ0 and visual extinctions within the range found for dusty globules in the Crab nebula, although far-infrared emission from [O I] and [C II] is higher than the observational constraints. Models with nH = 1900 cm-3 underpredict the H2 surface brightness, but agree with the ArH+ and OH+ surface brightnesses and predict [O I] and [C II] line ratios consistent with observations. These models predict HeH+ rotational emission above detection thresholds, but consideration of the formation time-scale suggests that the abundance of this molecule in the Crab nebula should be lower than the equilibrium values obtained in our analysis.

  11. Superallowed Branching Ratio in the β Decay of 34Ar (United States)

    Iacob, V. E.; Hardy, J. C.


    Precise ft-values for superallowed 0+ -->0+β+ -decays contribute to the most demanding unitarity test of the Cabibbo-Kobayashi-Maskawa matrix. The decays from Tz = -1 nuclei, like 34Ar, are particularly valuable because they can constrain the isospin symmetry-breaking corrections that must be applied to the measured ft-values. This requires their branching ratios to be determined to ~0.1% or better. We report here on our continuing quest to reach this goal, which most recently has involved better control of our detection geometry (with laser ranging) and continuous monitoring of dead-time. We produced a pure 34Ar beam at the exit of the MARS recoil separator using a 25A MeV 35Cl beam from the Texas A&M cyclotron to bombard a hydrogen gas target. The 34Ar beam was extracted into air, degraded and implanted into the Mylar tape of our fast transport system. In repeated cycles, each 34Ar sample was collected for 2s and then moved in 175 ms to the center of a well-shielded β - γ counting station, where β singles and β - γ coincidences were recorded for 2s. The β's were detected in a1-mm-thick plastic scintillator, while the γ's were detected by our precisely efficiency-calibrated HPGe detector. With the laser sensor we read the tape-to-HPGe distance to a precision better than 0.1mm and recorded it for each cycle. Branching-ratio results will be reported.

  12. Xenocrysts and antecrysts and their effect on the precision of 40Ar/39Ar dates of explosive volcanic eruption (United States)

    Smith, V.; Mark, D.; Blockley, S.; Weh, A.


    Evolved melts that fuel large explosive eruptions encounter, and are often generated through melting, crystal-rich parts of the magmatic system that fed previous eruptions. This results in many antecrysts being incorporated into the magma prior to eruption. In addition, many xenocrysts are entrained during eruption through conduit excavation. Combining all these crystal populations produces 40Ar/39Ar dates with wide-ranges, such as those that are often reported in the literature. In order to gain very precise dates of volcanic events it is thus necessary to assess whether antecrysts and xenocrysts effect the precision of the dates, and establish ways to reduce these components. Here we use the deposits of the ~11 ka Ulleung-Oki eruption from the alkaline volcanic island of Ulleung, situated 130 km east of the Korean peninsula. The eruption deposits are widely dispersed and found in the Suigetsu lake sequence from central Japan. A precise date of the tephra would help with construction of the terrestrial radiocarbon calibration curve that spans back to the limit of radiocarbon dating (~50 ka). The new calibration model is currently being constructed using varve chronology (annual layer counting) and >600 14C determinations of terrestrial macrofossils*. However, the annual layers stop shortly after the 2 cm-thick Ulleung-Oki tephra. Precise dates of this volcanic event using a method that is independent of radiocarbon dating, would help validate the chronology of the core, and test the validity of the radiocarbon calibration curve. The tephra in the core has been correlated to proximal deposits using major and trace element composition (determined using an electron microprobe and LA-ICPMS) of the glass shards that comprise the distal ash. The proximal Ulleung-Oki eruption deposits are sandine-rich with crystals that range from ~80 microns to a few millimetres in size. These are likely to be a mixture of phenocrysts, antecrysts and xenocrysts. In order to get a very

  13. Diamond provenance studies from 40Ar/ 39Ar dating of clinopyroxene inclusions: An example from the west coast of Namibia (United States)

    Phillips, D.; Harris, J. W.


    The west coast of Namibia is host to substantive detrital diamond deposits located in onshore and offshore beach gravels, desert deflation deposits and lower Orange river terraces. The origin of the Namibian diamonds is controversial, with some studies favouring derivation from distal Cretaceous/Jurassic kimberlites on the Kaapvaal craton, and others arguing that most diamonds originated from proximal Dwyka glacial deposits (~ 300 Ma), which incorporated diamonds from older (≥ 500 Ma), pre-Karoo kimberlites. Previous studies have demonstrated that clinopyroxene inclusions extracted from their host diamonds give 40Ar/ 39Ar ages approaching the time of source kimberlite eruption. This behaviour is attributed to diffusion of argon to lattice defect sites and the diamond/inclusion interface region during mantle residence, with subsequent loss of the latter component on cleaving of the diamond to release the inclusion(s). In this study, we measured 40Ar/ 39Ar ages of extracted clinopyroxene inclusions from Namibian detrital diamonds, in order to determine potential kimberlite sources, craton erosion histories and palaeo-drainage evolution in southern Africa. 40Ar/ 39Ar step-heating data were obtained for eclogitic and peridotitic clinopyroxene inclusions from 50 Namibian diamonds. Low temperature steps produced older apparent ages than high temperature (fusion) steps, consistent with partial retention of pre-eruption argon in defect sites. With one exception, fusion steps yielded younger ages, ranging from 62 ± 30 Ma to 1441 ± 700 Ma. The majority (80%) of inclusions have fusion ages < 300 Ma, indicating that most Namibian detrital diamonds originated from post-Dwyka (< 300 Ma) kimberlites. Six inclusion aliquots (13%) produced ages unique to Cretaceous Group I kimberlites, confirming erosion of diamonds from these sources. The proportion of diamonds sourced from Group II kimberlites is uncertain, although forward modelling suggests roughly equal quantities from

  14. Radiogenic argon loss in experimentally deformed muscovite and biotite determined by in situ ultraviolet laser ablation 40Ar/39Ar geochronology (Invited) (United States)

    Cosca, M. A.; Stünitz, H.; Bourgeix, A.


    40Ar/39Ar geochronology is often employed on micas in strongly deformed rocks as a means of dating deformation. Results from such studies, either single grains or multi-grain step-heating experiments, typically do not yield 40Ar/39Ar age plateaux. This could be due to heterogeneous radiogenic argon (40Ar*) concentrations reflecting diffusion length scales smaller than the grain radius in strongly deformed micas. To test this hypothesis, samples of non-deformed peraluminous granite from the South Armorican Massif, in northwestern France, have been experimentally deformed under high pressures to evaluate the effects of deformation on 40Ar* retentivity. Granite cores, 2 cm in length and 0.5 cm in diameter, were loaded into gold capsules and sealed in the presence of excess water. The samples were deformed within a solid medium assembly in a Griggs-type triaxial hydraulic deformation apparatus at a pressure of 10 kb and temperature of 600°C for 29 hours. Overall shortening during the experiments was approximately 10%. Transmitted light and secondary and backscattered electron imaging of the deformed samples reveals evidence for significant physical grain size reduction by kinking, cracking, and grain segmentation of the micas. Infrared laser incremental heating of separated single grains of muscovite and biotite from the non-deformed granite yield 40Ar/39Ar plateau ages of 311 ± 2 Ma (2σ) over nearly 100% of the gas released. 40Ar/39Ar ages obtained by in situ ultraviolet laser ablation (± 4-10%, 1σ) of deformed muscovites range from 310 Ma, overlapping the age of the non-deformed muscovite, to 263 Ma, consistent with about 16% 40Ar* loss; deformed biotite yielded ages of 301 Ma to 267 Ma, consistent with up to 15% 40Ar* loss. Calculation of expected 40Ar* loss from these experimental procedures and available diffusion data suggests that ages should be decreased by forming and annealing by dynamic deformation during orogenesis, is a potentially overlooked factor

  15. Composite GPS Patch Antenna for the AR Bandwidth Enhancement

    Directory of Open Access Journals (Sweden)

    Minkil Park


    Full Text Available A composite Global Positioning System (GPS patch antenna with a quadrature 3 dB hybrid coupler was designed and implemented for working RHCP and had a broadband axial ratio (AR bandwidth. We designed two patches as a FR-4 patch and 1.5 mm thickness thin ceramic patch with a quadrature 3 dB hybrid coupler. A CP radiation pattern was achieved, and the AR bandwidth improved by incorporating a quadrature 3 dB hybrid coupler feed structure in a micro-strip patch antenna. SMD by chip elements was applied to the quadrature 3 dB hybrid coupler. For the composite FR-4 and ceramic patch antennas, the VSWR measurement showed a 2 : 1 ratio over the entire design band, and the 3 dB AR bandwidth was 295 and 580 MHz for the FR-4 patch and ceramic patch antennas, respectively. The antenna gains for the composite FR-4 and ceramic patch antennas were measured as 1.36–2.75 and 1.47–2.71 dBi with 15.11–25.3% and 19.25–28.45% efficiency, respectively.

  16. DARGS: Dynamic AR Guiding System for Indoor Environments

    Directory of Open Access Journals (Sweden)

    Georg Gerstweiler


    Full Text Available Complex public buildings, such as airports, use various systems to guide people to a certain destination. Such approaches are usually implemented by showing a floor plan that has guiding signs or color coded lines on the floor. With a technology that supports six degrees of freedom (6DoF tracking in indoor environments, it is possible to guide people individually, thereby considering obstacles, path lengths, or pathways for handicapped people. With an augmented reality (AR device, such as a smart phone or AR glasses, the path can be presented on top of the real environment. In this paper, we present DARGS, an algorithm, which calculates a path through a complex building in real time. Usual path planning algorithms use either shortest paths or dynamic paths for robot interaction. The human factor in a real environment is not considered. The main advantage of DARGS is the incorporation of the current field of view (FOV of the used device to visualize a more dynamic presentation. Rather than searching for the AR content with a small FOV, with the presented approach the user always gets a meaningful three-dimensional overlay of the path independent of the viewing direction. A detailed user study is performed to prove the applicability of the system. The results indicate that the presented system is especially helpful in the first few important seconds of the guiding process, when the user is still disoriented.

  17. Thermal neutron induced (n,p) and (n,alpha) reactions on Ar-37

    NARCIS (Netherlands)

    Bieber, R; Wagemans, C; Goeminne, G; Wagemans, J; Denecke, B; Loiselet, M; Gaelens, M; Geltenbort, P; Oberhummer, H


    The Ar-37(n(th),alpha)S-34 and Ar-37(n(th),p)Cl-37 reactions were studied at the high flux reactor of the ILL in Grenoble, For the Ar-37(n(th),alpha(0))S-34 and Ar-37(n(th),p)Cl-37 reaction cross sections, values of (1070 +/- 80) b and (37 +/- 4) b, respectively, were obtained. Both values are about

  18. Regulatory Activities of Four ArsR Proteins in Agrobacterium tumefaciens 5A. (United States)

    Kang, Yoon-Suk; Brame, Keenan; Jetter, Jonathan; Bothner, Brian B; Wang, Gejiao; Thiyagarajan, Saravanamuthu; McDermott, Timothy R


    ArsR is a well-studied transcriptional repressor that regulates microbe-arsenic interactions. Most microorganisms have an arsR gene, but in cases where multiple copies exist, the respective roles or potential functional overlap have not been explored. We examined the repressors encoded by arsR1 and arsR2 (ars1 operon) and by arsR3 and arsR4 (ars2 operon) in Agrobacterium tumefaciens 5A. ArsR1 and ArsR4 are very similar in their primary sequences and diverge phylogenetically from ArsR2 and ArsR3, which are also quite similar to one another. Reporter constructs (lacZ) for arsR1, arsR2, and arsR4 were all inducible by As(III), but expression of arsR3 (monitored by reverse transcriptase PCR) was not influenced by As(III) and appeared to be linked transcriptionally to an upstream lysR-type gene. Experiments using a combination of deletion mutations and additional reporter assays illustrated that the encoded repressors (i) are not all autoregulatory as is typically known for ArsR proteins, (ii) exhibit variable control of each other's encoding genes, and (iii) exert variable control of other genes previously shown to be under the control of ArsR1. Furthermore, ArsR2, ArsR3, and ArsR4 appear to have an activator-like function for some genes otherwise repressed by ArsR1, which deviates from the well-studied repressor role of ArsR proteins. The differential regulatory activities suggest a complex regulatory network not previously observed in ArsR studies. The results indicate that fine-scale ArsR sequence deviations of the reiterated regulatory proteins apparently translate to different regulatory roles. Given the significance of the ArsR repressor in regulating various aspects of microbe-arsenic interactions, it is important to assess potential regulatory overlap and/or interference when a microorganism carries multiple copies of arsR This study explores this issue and shows that the four arsR genes in A. tumefaciens 5A, associated with two separate ars operons, encode

  19. Late Paleozoic deformation and exhumation in the Sierras Pampeanas (Argentina): 40Ar/39Ar-feldspar dating constraints (United States)

    Löbens, Stefan; Oriolo, Sebastián; Benowitz, Jeff; Wemmer, Klaus; Layer, Paul; Siegesmund, Siegfried


    Systematic 40Ar/39Ar feldspar data obtained from the Sierras Pampeanas are presented, filling the gap between available high- (> 300 °C) and low-temperature (< 150 °C) thermochronological data. Results show Silurian-Devonian exhumation related to the late stages of the Famatinian/Ocloyic Orogeny for the Sierra de Pocho and the Sierra de Pie de Palo regions, whereas the Sierras de San Luis and the Sierra de Comechingones regions record exhumation during the Carboniferous. Comparison between new and available data points to a Carboniferous tectonic event in the Sierras Pampeanas, which represents a key period to constrain the early evolution of the proto-Andean margin of Gondwana. This event was probably transtensional and played a major role during the evolution of the Paganzo Basin as well as during the emplacement of alkaline magmatism in the retroarc.

  20. Charge-exchange, ionization and excitation in low-energy Li$^{+}-$ Ar, K$^{+}-$ Ar, and Na$^{+}-$He collisions

    CERN Document Server

    Lomsadze, Ramaz A; Kezerashvili, RomanYa; Schulz, Michael


    Absolute cross sections are measured for charge-exchange, ionization, and excitation within the same experimental setup for the Li$^{+}-$Ar, K$^{+}-$ Ar, and Na$^{+}-$ He collisions in the ion energy range $0.5-10$ keV. Results of our measurements along with existing experimental data and the schematic correlation diagrams are used to analyze and determine the mechanisms for these processes. The experimental results show that the charge-exchange processes are realized with high probabilities and electrons are predominately captured in ground states. The cross section ratio for charge exchange, ionization and excitation processes roughly attains the value $10:2:1$, respectively. The contributions of various partial inelastic channels to the total ionization cross sections are estimated and a primary mechanism for the process is defined. The energy-loss spectrum, in addition, is applied to estimate the relative contribution of different inelastic channels and to determine the mechanisms for the ionization and f...

  1. Age of the youngest volcanism at Eagle Lake, northeastern California—40Ar/39Ar and paleomagnetic results (United States)

    Clynne, Michael A.; Calvert, Andrew T.; Champion, Duane E.; Muffler, L.J.P.; Sawlan, Michael G.; Downs, Drew T.


    The age of the youngest volcanism at Eagle Lake, California, was investigated using stratigraphic, paleomagnetic, and 40Ar/39Ar techniques. The three youngest volcanic lava flows at Eagle Lake yielded ages of 130.0±5.1, 127.5±3.2 and 123.6±18.7 ka, and are statistically indistinguishable. Paleomagnetic results demonstrate that two of the lava flows are very closely spaced in time, whereas the third is different by centuries to at most a few millennia. These results indicate that the basalt lava flows at Eagle Lake are not Holocene in age, and were erupted during an episode of volcanism at about 130–125 ka that is unlikely to have spanned more than a few thousand years. Thus, the short-term potential for subsequent volcanism at Eagle Lake is considered low. 

  2. Measuring the Perceived Quality of an AR-Based Learning Application: A Multidimensional Model (United States)

    Pribeanu, Costin; Balog, Alexandru; Iordache, Dragos Daniel


    Augmented reality (AR) technologies could enhance learning in several ways. The quality of an AR-based educational platform is a combination of key features that manifests in usability, usefulness, and enjoyment for the learner. In this paper, we present a multidimensional model to measure the quality of an AR-based application as perceived by…

  3. 75 FR 30750 - Drawbridge Operation Regulation; Arkansas Waterway, Little Rock, AR (United States)


    ..., Little Rock, AR AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast Guard... Waterway at mile 119.6 at Little Rock, AR, so that vessel operators will contact the remote drawbridge... the Baring Cross Railroad Drawbridge, mile 119.6, at Little Rock, AR is maintained in the closed...

  4. Through the Loupe: Visitor engagement with a primarily text-based handheld AR application

    NARCIS (Netherlands)

    van der Vaart, M.; Damala, A.; Guidi, G; Scopigno, R.; Torres, J.C.; Graf, H.; Remondino, F.; Duranti, L.; Brunet, P.; Hazan, S.; Barceló, J.


    The use of Augmented Reality (AR) in a museum or heritage setting holds great potential. However, until now, introducing AR into their buildings has been prohibitively expensive for most museums. On the one hand, programming the AR application could not be done in-house and would be rather costly.

  5. ArsR arsenic-resistance regulatory protein from Cupriavidus metallidurans CH34

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y.; van der Lelie, D.; Monchy, S.; Greenberg, B.; Gang, O.; Taghavi, S.


    The Cupriavidus metallidurans CH34 arsR gene, which is part of the arsRIC{sub 2}BC{sub 1}HP operon, and its putative arsenic-resistance regulatory protein were identified and characterized. The arsenic-induced transcriptome of C. metallidurans CH34 showed that the genes most upregulated in the presence of arsenate were all located within the ars operon, with none of the other numerous heavy metal resistance systems present in CH34 being induced. A transcriptional fusion between the luxCDABE operon and the arsR promoter/operator (P/O) region was used to confirm the in vivo induction of the ars operon by arsenite and arsenate. The arsR gene was cloned into expression vectors allowing for the overexpression of the ArsR protein as either his-tagged or untagged protein. The ability of the purified ArsR proteins to bind to the ars P/O region was analyzed in vitro by gel mobility shift assays. ArsR showed an affinity almost exclusively to its own ars P/O region. Dissociation of ArsR and its P/O region was metal dependent, and based on decreasing degrees of dissociation three groups of heavy metals could be distinguished: As(III), Bi(III), Co(II), Cu(II), Ni(II); Cd(II); Pb(II) and Zn(II), while no dissociation was observed in the presence of As(V).

  6. Multifold study of volume plasma chemistry in Ar/CF4 and Ar/CHF3 CCP discharges (United States)

    Proshina, O. V.; Rakhimova, T. V.; Zotovich, A. I.; Lopaev, D. V.; Zyryanov, S. M.; Rakhimov, A. T.


    Low-pressure RF plasma in fluorohydrocarbon gas mixtures is widely used in modern microelectronics, e.g. in the etching of materials with a low dielectric constant (low-k) materials). The multifold experimental and theoretical study of a radio frequency capacitively coupled plasma at 81 MHz in Ar/CF4/CHF3 has been carried out at 50 mTorr and 150 mTorr gas pressures. A wide set of experimental diagnostics together with hybrid PIC MC model calculations were applied to a detailed study of the plasmas. Measurements of the F atoms, HF molecules and CF x radicals, electron density, electronegativity and positive ion composition were performed. Absolutely calibrated VUV spectrometry was carried out to measure the VUV photon fluence towards the electrode. This combined experimental and model approach allowed us to establish the fundamental mechanisms of the charged and neutral species elementary reactions. Dissociative charge transfer reactions and fluoride transfer reactions influence the main ion (CF{}3+, CHF{}2+) composition in Ar/CF4/CHF3 plasma a lot. The mechanisms of heavy ion formation in Ar/CHF3 are also discussed. The important role of additional attachment mechanisms (besides dissociative attachment to the feedstock gases, CF4, CHF3) was analyzed. The catalytic chain mechanism, including the HF molecules, which defines the CF x kinetics in Ar/CHF3 plasma, was validated. This multifold approach enabled us to determine the complicated plasma chemical composition of the active species as well as the fluxes of VUV photons at the surface of the processed material, and is a result that is important for understanding low-k damage.

  7. Glycogen synthase kinase-3 inhibitors suppress the AR-V7-mediated transcription and selectively inhibit cell growth in AR-V7-positive prostate cancer cells. (United States)

    Nakata, Daisuke; Koyama, Ryokichi; Nakayama, Kazuhide; Kitazawa, Satoshi; Watanabe, Tatsuya; Hara, Takahito


    Recent evidence suggests that androgen receptor (AR) splice variants, including AR-V7, play a pivotal role in resistance to androgen blockade in prostate cancer treatment. The development of new therapeutic agents that can suppress the transcriptional activities of AR splice variants has been anticipated as the next generation treatment of castration-resistant prostate cancer. High-throughput screening of AR-V7 signaling inhibitors was performed using an AR-V7 reporter system. The effects of a glycogen synthase kinase-3 (GSK3) inhibitor, LY-2090314, on endogenous AR-V7 signaling were evaluated in an AR-V7-positive cell line, JDCaP-hr, by quantitative reverse transcription polymerase chain reaction. The relationship between AR-V7 signaling and β-catenin signaling was assessed using RNA interference. The effect of LY-2090314 on cell growth in various prostate cancer cell lines was also evaluated. We identified GSK3 inhibitors as transcriptional suppressors of AR-V7 using a high-throughput screen with an AR-V7 reporter system. LY-2090314 suppressed the reporter activity and endogenous AR-V7 activity in JDCaP-hr cells. Because silencing of β-catenin partly rescued the suppression, it was evident that the suppression was mediated, at least partially, via the activation of β-catenin signaling. AR-V7 signaling and β-catenin signaling reciprocally regulate each other in JDCaP-hr cells, and therefore, GSK3 inhibition can repress AR-V7 transcriptional activity by accumulating intracellular β-catenin. Notably, LY-2090314 selectively inhibited the growth of AR-V7-positive prostate cancer cells in vitro. Our findings demonstrate the potential of GSK3 inhibitors in treating advanced prostate cancer driven by AR splice variants. In vivo evaluation of AR splice variant-positive prostate cancer models will help illustrate the overall significance of GSK3 inhibitors in treating prostate cancer. © 2017 Wiley Periodicals, Inc.

  8. Constraints on the development of Proterozoic basins in central India from 40Ar/39Ar analysis of authigenic glauconitic minerals (United States)

    Conrad, J.E.; Hein, J.R.; Chaudhuri, A.K.; Patranabis-Deb, S.; Mukhopadhyay, J.; Deb, G.K.; Beukes, N.J.


    Ages of some key stratigraphic sequences in central Indian Proterozoic basins are based predominantly on lithostratigraphic relationships that have been constrained by only a few radioisotopic dates. To help improve age constraints, single grains of glauconitic minerals taken from sandstone and limestone in two Proterozoic sequences in the Pranhita-Godavari Valley and the Chattisgarh basin were analyzed by the 40Ar/39Ar incremental heating method. Analysis of the age spectra distinguishes between ages that are interpreted to reflect the time of glauconite formation, and anomalous ages that result from inherited argon or postcrystallization heating. The analyses indicate an age of 1686 ± 6 Ma for the Pandikunta Limestone and 1566 ± 6 Ma for the Ramgundam Sandstone, two units in the western belt of Proterozoic sequences in Pranhita-Godavari Valley. Glauconite from the Chanda Limestone, in the upper part of this sequence, contains inherited 40Ar but is interpreted to reflect an age of ca. 1200 Ma. Glauconite from the Somanpalli Group in the eastern belt of the Pranhita-Godavari Valley gives an age of 1620 ± 6 Ma. In the Chattisgarh basin, glauconite from two units gives disturbed ages that suggest a period of regional heating in the Chattisgarh basin at ca. 960–1000 Ma. These new ages indicate that these sequences are 200–400 m.y. older than previously recognized, which has important implications for geochemical studies of Mesoproterozoic ocean redox conditions in addition to providing important constraints on regional tectonics and lithostratigraphy.

  9. Mars Atmospheric History Derived from Upper-Atmospheric Structure of 38Ar/36Ar Measured From MAVEN (United States)

    Jakosky, Bruce; Slipski, Marek; Benna, Mehdi; Mahaffy, Paul; Elrod, Meredith K.; Yelle, Roger; Stone, Shane; Alsaeed, Noora


    Measurements of the structure of the Martian upper atmosphere made from MAVEN observations allow us to derive homopause and exobase altitudes in the Mars upper atmosphere and to determine the isotopic fractionation that occurs between them. Fractionation in the ratio of 38Ar/36Ar occurs between the homopause and exobase due to diffusive separation. This fractionation, combined with measurements of the bulk atmospheric ratio, is used to determine the total amount of argon lost to space by pick-up-ion sputtering. Our analysis is based on Rayleigh distillation, modified by replenishment of gas to the atmosphere by outgassing, impact, and crustal weathering. Approximately 80 % of the 36Ar that was ever in the atmosphere has been removed through time. This high value requires that a major fraction of Mars atmospheric gas has been lost to space. It points strongly to loss to space as having been the dominant mechanism driving the transition in Martian climate from an early, warm, wet environment to today's cold, dry, thin atmosphere.

  10. 40Ar- 39Ar dating of plagioclase grain size separates from silicate inclusions in IAB iron meteorites and implications for the thermochronological evolution of the IAB parent body (United States)

    Vogel, Nadia; Renne, Paul R.


    In order to better constrain the thermochronological evolution of the IAB parent body we performed a 40Ar/ 39Ar age study on individual silicate inclusions of the IAB irons Caddo County, Campo del Cielo, Landes, and Ocotillo. In contrast to earlier studies, several plagioclase separates of different grain sizes and quality grades were extracted from each inclusion to reduce the complexity of the age spectra and study the influence of these parameters on the Ar-Ar ages. In nearly all inclusions we found significantly different Ar-Ar ages among the separates (Caddo County: 4.472 ± 0.02-4.562 ± 0.02 Ga; Campo del Cielo 2: 4.362 ± 0.04-4.442 ± 0.03 Ga; Landes 2: 4.412 ± 0.05-4.522 ± 0.04 Ga; Ocotillo: 4.382 ± 0.04-4.462 ± 0.03 Ga). These ages were calculated using the new 40K decay constant published by [Mundil R., Renne P. R., Min K. and Ludwig K. R. (2006) Resolvable miscalibration of the 40Ar/ 39Ar geochronometer. Eos Trans. AGU 87, Fall Meet. Suppl., Abstract V21A-0543]. The ages did not systematically correlate with the respective grain size of the separate as expected, i.e., smaller grains did not necessarily show younger ages due to later closure to Ar diffusion or easier re-opening of the system in the course of a reheating event compared to larger grains. Based on the large range of Ar-Ar ages we suggest that the individual inclusions are composed of silicate grains from different locations within the IAB parent body. While some grains remained in a hot (deep) environment that allowed Ar diffusion over an extended time period—in some cases combined with grain coarsening—, others cooled significantly earlier (near surface) through the K/Ar blocking temperature. These different grains where brought together during an impact followed by mixing and reassembly of the debris as proposed by Benedix et al. [Benedix G. K., McCoy T. J., Keil K. and Love S. G. (2000) A petrologic study of the IAB iron meteorites: constraints on the formation of the IAB

  11. Coherence of the Dabie Shan UHPM terrane investigated by Lu-Hf and 40Ar/39Ar dating of eclogites (United States)

    Brouwer, F. M.; Groen, M.; Nebel, O.; Wijbrans, J. R.; Qiu, H.


    The Central China Orogenic Belt is the largest known ultrahigh-pressure metamorphic (UHPM) belt. Currently exposed UHP metamorphic rocks reflect subduction of massive swathes of continental crust to depths exceeding 100 km. Subsequent uplift exposed the voluminous sequence more or less intact. Deciphering responsible exhumation processes requires well constrained P-T-time paths. Most workers accept Triassic (~240 and 220-200 Ma) peak UHP metamorphism on the basis of zircon U-Pb ages in Central and Eastern Dabie Shan, while Western Dabie Shan, Qinling, North Qaidam and Altyn Tagh exhibit Ordovician (420-500 Ma) UHPM. However, contrasting reports of Carboniferous and Ordovian UHPM in Eastern Dabie Shan (Jian et al. 2001; Qiu & Wijbrans, 2006, 2008), and Ordovician, Carboniferous and Triassic (U)HPM in Western Dabie Shan (Wu et al. 2009) question this simple East-West gradient. Here, we investigate PTt-paths for localities throughout Dabie Shan to determine how far west the Triassic UHP event is documented, and how far east the Carboniferous and Ordovician events can be traced. Based on this distribution we aim to establish whether the Dabie Shan terrane is an amalgam of blocks that underwent UHPM at different times rather than a single coherent terrane. Eclogite samples are investigated for thermobarometry, Lu-Hf Grt-Cpx geochronology, and 40Ar/39Ar thermochronology. For fresh eclogites Thermocalc was used to establish equilibration conditions of the UHPM assemblage, Grt and Cpx of which were subsequently used for Lu-Hf isotope analysis. In addition, retrogressed eclogites, two fresh eclogites and two orthogneisses were analysed for 40Ar/39Ar isotope distributions in Phg, Bt, Amp and Kfs. Four fresh eclogites, all collected at reported UHP-localities confirm established PT-estimates for peak-metamorphism above the Coe-in reaction at 450-680 °C, with higher T for eastern Dabie. In one sample this is confirmed by the presence of a Coe inclusion in Cpx. Lu-Hf Grt

  12. Gephyrin-independent GABA(AR mobility and clustering during plasticity.

    Directory of Open Access Journals (Sweden)

    Fumihiro Niwa

    Full Text Available The activity-dependent modulation of GABA-A receptor (GABA(AR clustering at synapses controls inhibitory synaptic transmission. Several lines of evidence suggest that gephyrin, an inhibitory synaptic scaffold protein, is a critical factor in the regulation of GABA(AR clustering during inhibitory synaptic plasticity induced by neuronal excitation. In this study, we tested this hypothesis by studying relative gephyrin dynamics and GABA(AR declustering during excitatory activity. Surprisingly, we found that gephyrin dispersal is not essential for GABA(AR declustering during excitatory activity. In cultured hippocampal neurons, quantitative immunocytochemistry showed that the dispersal of synaptic GABA(ARs accompanied with neuronal excitation evoked by 4-aminopyridine (4AP or N-methyl-D-aspartic acid (NMDA precedes that of gephyrin. Single-particle tracking of quantum dot labeled-GABA(ARs revealed that excitation-induced enhancement of GABA(AR lateral mobility also occurred before the shrinkage of gephyrin clusters. Physical inhibition of GABA(AR lateral diffusion on the cell surface and inhibition of a Ca(2+ dependent phosphatase, calcineurin, completely eliminated the 4AP-induced decrease in gephyrin cluster size, but not the NMDA-induced decrease in cluster size, suggesting the existence of two different mechanisms of gephyrin declustering during activity-dependent plasticity, a GABA(AR-dependent regulatory mechanism and a GABA(AR-independent one. Our results also indicate that GABA(AR mobility and clustering after sustained excitatory activity is independent of gephyrin.

  13. Production and release rate of 37Ar from the UT TRIGA Mark-II research reactor. (United States)

    Johnson, Christine; Biegalski, Steven R; Artnak, Edward J; Moll, Ethan; Haas, Derek A; Lowrey, Justin D; Aalseth, Craig E; Seifert, Allen; Mace, Emily K; Woods, Vincent T; Humble, Paul


    Air samples were taken at various locations around The University of Texas at Austin's TRIGA Mark II research reactor and analyzed to determine the concentrations of 37Ar, 41Ar, and 133Xe present. The measured ratio of 37Ar/41Ar and historical records of 41Ar releases were then utilized to estimate an annual average release rate of 37Ar from the reactor facility. Using the calculated release rate, atmospheric transport modeling was performed in order to determine the potential impact of research reactor operations on nearby treaty verification activities. Results suggest that small research reactors (∼1 MWt) do not release 37Ar in concentrations measurable by currently proposed OSI detection equipment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Estudio del sistema simbiótico AR Pavonis (United States)

    Quiroga, C.; Brandi, E.; Ferrer, O.; García, L.; Barbá, R.

    Se presenta un estudio espectroscópico y polarimétrico de la binaria eclipsante AR Pavonis a partir de observaciones obtenidas con el telescopio de 2.15 m. del CASLEO (San Juan). El estudio de la naturaleza del sistema se realizó a través del análisis de algunos espectros reunidos entre los años 1990 y 1995 y de datos polarimétricos correspondientes al intervalo 1995 y 1997. El análisis espectroscópico indica que AR Pav está compuesta por una gigante roja M3.7 y una componente caliente compacta, con una temperatura mayor a 90000 K y una luminosidad del orden de 500Lsolar. A lo largo del período orbital, las variaciones observadas en flujo y en velocidades radiales, reflejan que las emisiones permitidas se forman en una región que rodea la componente caliente. El estudio de la polarización lineal de AR Pav indica que además de una componente interestelar, existe una componente intrínseca del sistema que varía temporalmente y con la longitud de onda de la luz polarizada. El distinto comportamiento del grado de polarización y del ángulo de posición observado en fases diferentes, sugiere que distintos mecanismos pueden estar actuando, dependiendo de la región de scattering observado a lo largo de la línea de la visual.

  15. Superdeformation in Asymmetric N$>$Z Nucleus $^{40}$Ar

    CERN Document Server

    Ideguchi, E; Morikawa, T; Oshima, M; Koizumi, M; Toh, Y; Kimura, A; Harada, H; Furutaka, K; Nakamura, S; Kitatani, F; Hatsukawa, Y; Shizuma, T; Sugawara, M; Miyatake, H; Watanabe, Y X; Hirayama, Y; Oi, M


    A rotational band with five $\\gamma$-ray transitions ranging from 2$^{+}$ to 12$^{+}$ states was identified in $^{40}$Ar. This band is linked through $\\gamma$ transitions from the excited 2$^{+}$, 4$^{+}$ and 6$^{+}$ levels to the low-lying states; this determines the excitation energy and the spin-parity of the band. The deduced transition quadrupole moment of 1.45$^{+0.49}_{-0.31} eb$ indicates that the band has a superdeformed shape. The nature of the band is revealed by cranked Hartree--Fock--Bogoliubov calculations and a multiparticle--multihole configuration is assigned to the band.

  16. Superdeformation in asymmetric N>Z nucleus {sup 40}Ar

    Energy Technology Data Exchange (ETDEWEB)

    Ideguchi, E., E-mail: [Center for Nuclear Study, University of Tokyo, Wako, Saitama 351-0198 (Japan); Ota, S. [Center for Nuclear Study, University of Tokyo, Wako, Saitama 351-0198 (Japan); Morikawa, T. [Department of Physics, Kyushu University, Hakozaki, Fukuoka 812-8581 (Japan); Oshima, M.; Koizumi, M.; Toh, Y.; Kimura, A.; Harada, H.; Furutaka, K.; Nakamura, S.; Kitatani, F.; Hatsukawa, Y.; Shizuma, T. [Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan); Sugawara, M. [Chiba Institute of Technology, Narashino, Chiba 275-0023 (Japan); Miyatake, H.; Watanabe, Y.X.; Hirayama, Y. [Institute of Particle and Nuclear Studies, High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Oi, M. [Institute of Natural Sciences, Senshu University, Tokyo 101-8425 (Japan)


    A rotational band with five gamma-ray transitions ranging from 2{sup +} to 12{sup +} states was identified in {sup 40}Ar. This band is linked through gamma transitions from the excited 2{sup +}, 4{sup +} and 6{sup +} levels to the low-lying states; this determines the excitation energy and the spin-parity of the band. The deduced transition quadrupole moment of 1.45{sub -0.31}{sup +0.49}+-0.15 eb indicates that the band has a superdeformed shape. The nature of the band is revealed by cranked Hartree-Fock-Bogoliubov calculations and a multiparticle-multihole configuration is assigned to the band.

  17. A global potential energy surface for ArH2 (United States)

    Schwenke, David W.; Walch, Stephen P.; Taylor, Peter R.


    We describe a simple analytic representation of the ArH2 potential energy surface which well reproduces the results of extensive ab initio electronic structure calculations. The analytic representation smoothly interpolates between the dissociated H2 and strong bonding limits. In the fitting process, emphasis is made on accurately reproducing regions of the potential expected to be important for high temperature (ca. 3000 K) collision processes. Overall, the anisotropy and H2 bond length dependence of the analytic representation well reproduce the input data.

  18. El cultivo del arándano en Asturias


    García, J.C. (Juan)


    Los arándanos cultivados pertenecen a variedades en las que se ha tenido en cuenta una serie de consideraciones como las horas de frío en las zonas de cultivo y la época de maduración. Conviene escoger variedades muy productivas y adaptadas a la zona. Según la época de maduración de los frutos, los cultivares se pueden clasificar en muy tempranos, tempranos, de media estación, tardíos y muy tardíos.A parte de variedades, se estudian en este artículo: los requerimientos de clima y suelo, prep...

  19. Multi-particle Emission from $^{31}$Ar at ISOLDE

    CERN Document Server

    Marroquin, I; Ciemny, A A; de Witte, H; Fraile, L M; Fynbo, H O U; Garzón-Camacho, A; Howard, A; Johansson, H; Jonson, B; Kirsebom, O S; Koldste, G T; Lica, R; Lund, M V; Madurga, M; Mazzocchi, C; Mihai, C; Munch, M; Nae, S A; Nacher, E; Negret, A; Nilsson, T; Perea, A; Refsgaard, J; Riisager, K; Rapisarda, E; Sotty, C; Stanoiu, M; Tengblad, O; Turturica, A E; Vedia, M V


    A multi-particle decay experiment was successfully performed at the ISOLDE Decay Station. In this new permanent station, devoted to\\break $\\beta$-decay studies, the novel MAGISOL Si-Plugin Chamber was installed to study the exotic decay modes of the proton drip-line nucleus ${^{31}}$Ar. The motivation was to search for $\\beta3p$ and $\\beta3p\\gamma$ channels, as well as to provide information on resonances in ${^{30}}$S and ${^{29}}$P relevant for the astrophysical\\break rp-process. Description of the experimental set-up and preliminary results are presented.

  20. Formation of AR-SMRT binding in prostate cancer cells treated with natural histone deacetylase inhibitor. (United States)

    Trtková, Kateřina; Pašková, Lenka; Matiješčuková, Natálie; Kolář, Zdeněk


    Signaling through the androgen receptor (AR) plays a critical role in prostate cancer progression. The AR is a classical nuclear receptor (NR) providing a link between signaling molecule and transcription response. Histone deacetylase inhibitors (HDACI) have antiproliferative and proapoptotic effects on prostate cancer cells and their implication in silence AR signaling may have potential therapeutic use. We aimed to study the inhibitory effects of the corepressor SMRT (Silencing Mediator for Retinoid and Thyroid hormone receptors) which forms a complex together with nuclear receptor corepressor (N-CoR) and with histone deacetylase 3 (HDAC3) on AR activity. The androgen-sensitive prostate cancer cell line LNCaP and androgen-insensitive prostate cancer cell line C4-2 both AR-positive, and androgen-insensitive DU145 and PC3 prostate cancer cell lines were treated with two HDACIs, sodium butyrate (NaB) and/or trichostatin A (TSA). We amplified immunoprecipitated DNA by conventional PCR and in the following step we used the chromatin immunoprecipitation (ChIP) analysis coupled with quantitative PCR for monitoring NaB induced formation of AR-SMRT/N-CoR complex binding on the PSA promoter. The co-immunoprecipitation assay revealed increase in AR-SMRT formation in NaB treated cells. Simultaneously, the Western blot analysis showed a significant decrease in AR protein expression. Furthermore, we estimated the reduced presence of HDAC2 and HDAC3 proteins by NaB and TSA treatment in AR-negative DU145 cell line. In conclusion, the inhibitory effect of NaB on AR gene expression seems to be specific and unique for prostate cancer AR-positive cell lines and corresponds with its ability to stimulate AR-SMRT complex formation. We suggest that AR and SMRT/N-CoR corepressors may form a stable complex in vitro and NaB may facilitate the interaction between AR nuclear steroid receptor and SMRT corepressor protein.

  1. Noble Gases in the Monahans Chondrite and Halite: Ar-39 - Ar-40 Age, Space Exposure Age, Trapped Solar Gases, and Neutron Fluence (United States)

    Garrison, Daniel H.; Bogard, Donald D.


    For the Monahans chondrite and halite, we determined Ar-39 - Ar-40 ages of silicate = 4.53 Ga, halite > 4.3 Ga; a space exposure age of approx. 5 Ma; a regolith pre-irradiation; solar gas concentrations in the dark phase; and a regolith thermal neutron fluence.

  2. Alpine orogenic evolution from subduction to collisional thermal overprint: The 40Ar/39Ar age constraints from the Valaisan Ocean, central Alps

    DEFF Research Database (Denmark)

    Wiederkehr, Michael; Sudo, Masafumi; Bousquet, Romain


    in general. The timing of high-pressure metamorphism, subsequent retrogression and following Barrow-type overprint was studied by 40Ar/39Ar dating of biotite and several white mica generations that are well characterized in terms of mineral chemistry, texture and associated mineral assemblages. Four distinct...

  3. 40Ar/39Ar dating of Quaternary volcanic ashes by multi-collection noble gas mass spectrometry: protocols, precision and intercalibration

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    -calibration and instrument mass fractionation using argon from a calibrated air pipette; (ii) precision and long-term data reproducibility; and (iii) results from inter-calibration experiments of 40Ar/39Ar ages on Quaternary volcanic ashes with the U-Pb, astronomical and historical chronometers....

  4. Newly registered small grains cultivars from Zaječar

    Directory of Open Access Journals (Sweden)

    Dodig Dejan


    Full Text Available The paper presents principal properties of 5 new cultivars of small grains created in the Center for Agricultural and Technological Research in Zaječar. They are as follows: Arena (winter bread wheat, Premium (winter malting barley, Tango (winter triticale, Center (spring oat and Balsa (spring naked barley. In 2004 and 2005 these cultivars were registered by the Ministry of Agriculture, Forestry and Water Management of the Republic of Serbia. The Arena cultivar has good indices of technological quality and high yield genetic potential which is successfully preserved even in dry years. The Premium cultivar, besides high yield capacity, has a very low protein grain content what makes it especially suitable for brewers industry. Triticale Tango is intended, in the first place, for animal feeds and like Arena cultivar. is highly tolerant to draught. Spring oat Center is Zaječar's first made oat cultivar in this group of small grains. Cultivar Balsa is the first spring six-row naked barley in Serbia and Montenegro. Creating of Balsa cultivar is the attempt to meet the future demands on the market. By the act of registering above mentioned cultivars the Center in Zajecar has completed and enlarged its already existing variety of small grains assortment.

  5. archAR: an archaeological augmented reality experience (United States)

    Wiley, Bridgette; Schulze, Jürgen P.


    We present an application for Android phones or tablets called "archAR" that uses augmented reality as an alternative, portable way of viewing archaeological information from UCSD's Levantine Archaeology Laboratory. archAR provides a unique experience of flying through an archaeological dig site in the Levantine area and exploring the artifacts uncovered there. Using a Google Nexus tablet and Qualcomm's Vuforia API, we use an image target as a map and overlay a three-dimensional model of the dig site onto it, augmenting reality such that we are able to interact with the plotted artifacts. The user can physically move the Android device around the image target and see the dig site model from any perspective. The user can also move the device closer to the model in order to "zoom" into the view of a particular section of the model and its associated artifacts. This is especially useful, as the dig site model and the collection of artifacts are very detailed. The artifacts are plotted as points, colored by type. The user can touch the virtual points to trigger a popup information window that contains details of the artifact, such as photographs, material descriptions, and more.

  6. An industrial approach to design compelling VR and AR experience (United States)

    Richir, Simon; Fuchs, Philippe; Lourdeaux, Domitile; Buche, Cédric; Querrec, Ronan


    The convergence of technologies currently observed in the field of VR, AR, robotics and consumer electronic reinforces the trend of new applications appearing every day. But when transferring knowledge acquired from research to businesses, research laboratories are often at a loss because of a lack of knowledge of the design and integration processes in creating an industrial scale product. In fact, the innovation approaches that take a good idea from the laboratory to a successful industrial product are often little known to researchers. The objective of this paper is to present the results of the work of several research teams that have finalized a working method for researchers and manufacturers that allow them to design virtual or augmented reality systems and enable their users to enjoy "a compelling VR experience". That approach, called "the I2I method", present 11 phases from "Establishing technological and competitive intelligence and industrial property" to "Improvements" through the "Definition of the Behavioral Interface, Virtual Environment and Behavioral Software Assistance". As a result of the experience gained by various research teams, this design approach benefits from contributions from current VR and AR research. Our objective is to validate and continuously move such multidisciplinary design team methods forward.

  7. Re-measurement of $^{32}$Ar to test the IMME

    CERN Multimedia

    The Isobaric Multiplet Mass Equation (IMME) has been subject to extensive studies in the low-mass region. Especially at the A = 32 quintet, the predicted quadratic form could not be confirmed, possible explanations being the insufficient accuracy of input parameters or higher-order interactions within the nucleon. For this quintet, the uncertainty on the mass-excess values of four of the five T = 2 multiplet members is extremely low: 0.6 keV for $^{32}$Cl, 0.3 keV for $^{32}$S, 0.2 keV for $^{32}$P, and 0.7 keV for $^{32}$Si. In the case of $^{32}$Ar, however, the uncertainty is as large as 1.8 keV. State-of-the-art high-precision Penning-trap mass spectrometry makes it possible to decrease this uncertainty. We propose to remeasure the mass of $^{32}$Ar at the Penning-trap mass spectrometer ISOLTRAP thus decreasing the uncertainty by a factor of 3-5. The proposed measurement is part of an experimental collaboration with JYFLTRAP, where the remaining masses of the T = 2 isospin quintet at A = 32 will be remeas...

  8. EyeAR: Refocusable Augmented Reality Content through Eye Measurements

    Directory of Open Access Journals (Sweden)

    Damien Constantine Rompapas


    Full Text Available Augmented Reality (AR superimposes computer graphics (CG onto a user’s view of the real world. A key quality problem in this field is to achieve coherence between reality and CG when the user’s eyes refocus or change pupil size. We designed and evaluated a display that improves coherence by measuring the user’s eye state and continuously adapting CG accordingly. Our tabletop prototype emulates an Optical See-Through Head-Mounted Display, a common AR display device. In our evaluation, participants observed three pillars at different depths. We then challenged them to identify a virtual pillar among the three while freely refocusing their eyes. Results show that our design significantly improved realism. Compared to Light Field Displays, our design aims to simplify display-optics while providing similar quality. We could only partially achieve this goal. We discuss the lessons we learned and how we plan to overcome the remaining challenges. The experimental protocol from our evaluation is useful for display developers as it can be used to measure the coherence of a display.

  9. Decision Support System for Aquifer Recharge (AR) and ... (United States)

    Aquifer recharge (AR) is a technical method being utilized to enhance groundwater resources through man-made replenishment means, such as infiltration basins and injections wells. Aquifer storage and recovery (ASR) furthers the AR techniques by withdrawal of stored groundwater at a later time for beneficial use. It is a viable adaptation technique for water availability problems. Variants of the water storage practices include recharge through urban green infrastructure and the subsurface injection of reclaimed water, i.e., wastewater, which has been treated to remove solids and impurities. In addition to a general overview of ASR variations, this report focuses on the principles and technical basis for an ASR decision support system (DSS), with the necessary technical references provided. The DSS consists of three levels of tools and methods for ASR system planning and assessment, design, and evaluation. Level 1 of the system is focused on ASR feasibility, for which four types of data and technical information are organized around: 1) ASR regulations and permitting needs, 2) Water demand projections, 3) Climate change and water availability, and 4) ASR sites and technical information. These technical resources are integrated to quantify water availability gaps and the feasibility of using ASR to meet the volume and timing of the water resource shortages. A systemic analysis of water resources was conducted for sustainable water supplies in Las Vegas, Nevada f

  10. Enhanced sources of acoustic power surrounding AR 11429 (United States)

    Donea, Alina; Hanson, Christopher


    Multi-frequency power maps of the local acoustic oscillations show acoustic enhancements ("acoustic-power halos") at high frequencies surrounding large active region. Computational seismic holography reveals a high-frequency "acoustic-emission halo", or "seismic glory" surrounding large active regions. In this study, we have applied computational seismic holography to map the seismic seismic source density surrounding AR 11429. Studies of HMI/SDO Doppler data, shows that the "acoustic halos" and the "seismic glories" are prominent at high frequencies 5-8 mHz. We investigate morphological properties of acoustic-power and acoustic emission halos around an active region to see if they are spatially correlated. Details about the local magnetic field from vectormagnetograms of AR 11429 are included. We identify a 15" region of seismic deficit power (dark moat) shielding the white-light boundary of the active region. The size of the seismic moat is related to region of intermediate magnetic field strength. The acoustic moat is circled by the halo of enhanced seismic amplitude as well as enhanced seismic emission. Overall, the results suggest that features are related. However, if we narrow the frequency band to 5.5 - 6.5 mHz, we find that the seismic source density dominates over the local acoustic power, suggesting the existence of sources that emit more energy downward into the solar interior than upward toward the solar surface.

  11. Scientia sexualis versus ars erotica: Foucault, van Gulik, Needham. (United States)

    Rocha, Leon Antonio


    This paper begins with a discussion of the scientia sexualis/ars erotica distinction, which Foucault first advances in History of Sexuality Vol. 1, and which has been employed by many scholars to do a variety of analytical work. Though Foucault has expressed his doubts regarding his conceptualization of the differences between Western and Eastern discourses of desire, he never entirely disowns the distinction. In fact, Foucault remains convinced that China must have an ars erotica. I will explore Foucault's sources of authority. To this end, I introduce the work of famous Dutch sinologist Robert Hans van Gulik, who published the tremendously influential Sexual Life in Ancient China in 1961, and also explore Joseph Needham's view on Chinese sex. I argue that, Foucault, in his fierce polemic against the "Repressive Hypothesis", himself imagined a utopian Other where pleasure and desire were organised differently. I end on a discuss on Orientalism and the project of "Sinography" of comparative literature scholars Haun Saussy, Eric Hayot and others. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Mesozoic thermal history and timing of structural events for the Yukon-Tanana Upland, east-central Alaska: 40Ar/39Ar data from metamorphic and plutonic rocks (United States)

    Dusel-Bacon, C.; Lanphere, M.A.; Sharp, W.D.; Layer, P.W.; Hansen, V.L.


    We present new 40Ar/39Ar ages for hornblende, muscovite, and biotite from metamorphic and plutonic rocks from the Yukon-Tanana Upland, Alaska. Integration of our data with published 40Ar/39Ar, kinematic, and metamorphic pressure (P) and temperature (T) data confirms and refines the complex interaction of metamorphism and tectonism proposed for the region. The oldest metamorphic episode(s) postdates Middle Permian magmatism and predates the intrusion of Late Triassic (215-212 Ma) granitoids into the Fortymile River assemblage (Taylor Mountain assemblage of previous papers). In the eastern Eagle quadrangle, rapid and widespread Early Jurassic cooling is indicated by ???188-186 Ma 40Ar/39Ar plateau ages for hornblende from plutons that intrude the Fortymile River assemblage, and for metamorphic minerals from the Fortymile River assemblage and the structurally underlying Nasina assemblage. We interpret these Early Jurassic ages to represent cooling resulting from northwest-directed contraction that emplaced the Fortymile River assemblage onto the Nasina assemblage to the north as well as the Lake George assemblage to the south. This cooling was the final stage of a continuum of subduction-related contraction that produced crustal thickening, intermediate- to high-P metamorphism within both the Fortymile River assemblage and the structurally underlying Lake George assemblage, and Late Triassic and Early Jurassic plutonism in the Fortymile River and Nasina assemblages. Although a few metamorphic samples from the Lake George assemblage yield Jurassic 40Ar/39Ar cooling ages, most yield Early Cretaceous 40Ar/39Ar ages: hornblende ???135-115 Ma, and muscovite and biotite ???110-108 Ma. We interpret the Early Cretaceous metamorphic cooling, in most areas, to have resulted from regional extension and exhumation of the lower plate, previously tectonically thickened during Early Jurassic and older convergence.

  13. Magnetostratigraphy and 40Ar/39Ar dating of CAMP lava flows at the Triassic-Jurassic boundary, Morocco (United States)

    Knight, K. B.; Nomade, S.; Renne, P.; Marzoli, A.; Youbi, N.


    The Central Atlantic Magmatic Province (CAMP), the largest known flood basalt province in the Phanerozoic, is generally associated with the incipient opening of the Atlantic Ocean at the Triassic-Jurassic boundary ca. 200 Ma. Paleomagnetic sampling targeted packages of CAMP lava flows in central Morocco from condensed sections identified on the basis of field observations and geochemistry. Lava flows in Moroccan CAMP are divided into four basic units, each comprising multiple flows (after Bertrand, 1991): the Formation (Fm.) Inférieure, Fm. Intermédiaire, Fm. Supérieure, and at the top, the Récurrente, separated from the first three by a period of red clay deposition. Oriented cores were demagnetized using both alternating field (AF) and thermal techniques. Cores from the same lava flow processed by AF demagnetization were later crushed for subsequent separation of plagioclase and dated by the 40Ar/39Ar method. Paleomagnetic results reveal wholly normal polarity interrupted by a brief reversal event defined by data from a single flow located at the base of the Fm. Intermédiaire. Preliminary results from a 250 m section of lavas spanning three formations in the Haut Atlas of Morocco confirm the presence of this brief reversal. 40Ar/39Ar analyses of these samples yielded six plateau ages including each formation. These ages are indistinguishable within 2σ error limits, sharing a mean age of 200.9 ± 0.7 Ma (2σ) relative to the Fish Canyon sanidine at 28.02 Ma (Renne et al., 1998). This demonstrates the brevity of these eruptions despite the presence of significant sedimentary horizons between them. These ages are slightly older than the average elsewhere around Pangea, suggesting CAMP volcanism initiated in Morocco and may span the Triassic-Jurassic transition. Correlation of our observed reversal with the E23n, E23r, E24 sequence reported in the Newark basin (Olsen et al., 2003) would further support this. These new data also contribute to the

  14. Earth radiation budgets in IPCC AR4 GCMs (United States)

    Wild, M.


    Substantial uncertainty still exists regarding the distribution of radiative energy within the global climate system, and its representation in General Circulation Models. Compared to a comprehensive set of surface observations, the majority of the GCMs participating in the latest IPCC forth assessment report (AR4) overestimate the surface insolation, by 6 Wm-2 on average, while the bias is smaller at the TOA (Wild 2008). This is in line with an analysis of 20 earlier GCMs participating in the Atmospheric Model Intercomparison Project AMIP II and suggests that the GCM atmospheres are still overly transparent for solar radiation (Wild 2005). Based on observational clear-sky climatologies at worldwide distributed anchor sites from the Baseline Surface Radiation Network (BSRN) and the Atmospheric Radiation Measurement Program (ARM) it is shown, that the surface insolation is also overestimated under cloud-free conditions in many GCMs with comparatively low atmospheric clear-sky solar absorption (around 60 Wm-2 in the global mean) (Wild et al. 2006). This identifies an overly transparent cloud-free atmosphere as a key error source for the long known problem of excessive surface insolation in GCMs. However, there are now several models participating in IPCC-AR4 with higher atmospheric clear-sky absorption (70 Wm-2 and up, globally averaged) and more realistic aerosol treatment, which are in excellent agreement with the observational clear-sky climatologies. This underlines the progress made in radiative transfer modeling as well as in the observation and diagnosis of solar radiation under cloudless atmospheres (Wild 2008). The most difficult component to model in the longwave is the downward longwave flux at the surface. Accordingly, large discrepancies exist in the global means of this component in the GCMs, both under all sky and clear sky conditions. A comparison with available observations from GEBA and BSRN suggests that the IPCC AR4 GCMs tend to underestimate the

  15. Serial blood-based analysis of AR-V7 in men with advanced prostate cancer (United States)

    Nakazawa, M.; Lu, C.; Chen, Y.; Paller, C. J.; Carducci, M. A.; Eisenberger, M. A.; Luo, J.; Antonarakis, E. S.


    Background We previously showed that pretreatment detection of androgen receptor splice variant-7 (AR-V7) in circulating tumor cells (CTCs) from men with castration-resistant prostate cancer is associated with resistance to abiraterone and enzalutamide, but not to taxane chemotherapies. Here, we conducted serial measurements of AR-V7 and evaluated patterns of longitudinal AR-V7 dynamics over the course of multiple sequential therapies. Patients and methods Metastatic prostate cancer patients treated at Johns Hopkins with AR-directed therapies or taxane chemotherapies underwent serial liquid biopsies for CTC-based AR-V7 analysis at baseline, during therapy, and at progression. We used a CTC enrichment platform followed by multiplexed reverse-transcription polymerase chain reaction analysis to detect full-length androgen receptor and AR-V7 transcripts. Patients selected for inclusion in this report were those who provided ≥4 CTC samples, at least one of which was AR-V7 positive, over the course of ≥2 consecutive therapies. Results We identified 14 patients who received a total of 37 therapies and contributed 70 CTC samples for AR-V7 analysis during a median follow-up period of 11 months. Three patients remained AR-V7 positive during the entire course of therapy. The remainder underwent transitions in AR-V7 status: there were eight instances of ‘conversions’ from AR-V7-negative to -positive status (during treatment with first-line androgen deprivation therapy, abiraterone, enzalutamide, and docetaxel), and six instances of ‘reversions’ from AR-V7-positive to -negative status (during treatment with docetaxel and cabazitaxel). Conclusions AR-V7 is a dynamic marker, and transitions in AR-V7 status may reflect selective pressures on the tumor exerted by therapeutic interventions. While ‘conversions’ to AR-V7-positive status were observed with both AR-directed therapies and taxane chemotherapies, ‘reversions’ to AR-V7-negative status only occurred

  16. Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection. (United States)

    Hoang, Ky V; Borteh, Hassan M; Rajaram, Murugesan V S; Peine, Kevin J; Curry, Heather; Collier, Michael A; Homsy, Michael L; Bachelder, Eric M; Gunn, John S; Schlesinger, Larry S; Ainslie, Kristy M


    AR-12 has been evaluated in clinical trials as an anti-cancer agent but also has demonstrated host-directed, broad-spectrum clearance of bacteria. We have previously shown that AR-12 has activity in vitro against Salmonella enterica serovar Typhimurium and Francisella species by inducing autophagy and other host immune pathways. AR-12 treatment of S. Typhimurium-infected mice resulted in a 10-fold reduction in bacterial load in the liver and spleen and an increased survival time. However, AR-12 treatment did not protect mice from death, likely due poor formulation. In the current study, AR-12 was encapsulated in a microparticulate carrier formulated from the novel degradable biopolymer acetalated dextran (Ace-DEX) and subsequently evaluated for its activity in human monocyte-derived macrophages (hMDMs). Our results show that hMDMs efficiently internalized Ace-DEX microparticles (MPs), and that encapsulation significantly reduced host cell cytotoxicity compared to unencapsulated AR-12. Efficient macrophage internalization of AR-12 loaded MPs (AR-12/MPs) was further demonstrated by autophagosome formation that was comparable to free AR-12 and resulted in enhanced clearance of intracellular Salmonella. Taken together, these studies provide support that Ace-DEX encapsulated AR-12 may be a promising new therapeutic agent to control intracellular bacterial pathogens of macrophages by targeting delivery and reducing drug toxicity. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. A pulsed plasma jet with the various Ar/N2 mixtures (United States)

    Barkhordari, A.; Ganjovi, A.; Mirzaei, I.; Falahat, A.; Rostami Ravari, M. N.


    In this paper, using the Optical Emission Spectroscopy technique, the physical properties of a fabricated pulsed DBD plasma jet are studied. Ar/N2 gaseous mixture is taken as operational gas, and Ar contribution in Ar/N2 mixture is varied from 75 to 95%. Through the optical emission spectra analysis of the pulsed DBD plasma jet, the rotational, vibrational and excitation temperatures and density of electrons in plasma medium of the pulsed plasma jet are obtained. It is seen that, at the wavelength of 750.38 nm, the radiation intensity from the Ar 4p → 4 s transition increases at the higher Ar contributions in Ar/N2 mixture. It is found that, for 95% of Ar presence in the mixture, the emission intensities from argon and molecular nitrogen are higher, and the emission line intensities will increase nonlinearly. In addition, it is observed that the quenching of Ar* by N2 results in the higher intensities of N2 excited molecules. Moreover, at the higher percentages of Ar in Ar/N2 mixture, while all the plasma temperatures are increased, the plasma electron density is reduced.

  18. Incremental heating of Bishop Tuff sanidine reveals preeruptive radiogenic Ar and rapid remobilization from cold storage (United States)

    Andersen, Nathan L.; Jicha, Brian R.; Singer, Brad S.; Hildreth, Wes


    Accurate and precise ages of large silicic eruptions are critical to calibrating the geologic timescale and gauging the tempo of changes in climate, biologic evolution, and magmatic processes throughout Earth history. The conventional approach to dating these eruptive products using the 40Ar/39Ar method is to fuse dozens of individual feldspar crystals. However, dispersion of fusion dates is common and interpretation is complicated by increasingly precise data obtained via multicollector mass spectrometry. Incremental heating of 49 individual Bishop Tuff (BT) sanidine crystals produces 40Ar/39Ar dates with reduced dispersion, yet we find a 16-ky range of plateau dates that is not attributable to excess Ar. We interpret this dispersion to reflect cooling of the magma reservoir margins below ˜475 °C, accumulation of radiogenic Ar, and rapid preeruption remobilization. Accordingly, these data elucidate the recycling of subsolidus material into voluminous rhyolite magma reservoirs and the effect of preeruptive magmatic processes on the 40Ar/39Ar system. The youngest sanidine dates, likely the most representative of the BT eruption age, yield a weighted mean of 764.8 ± 0.3/0.6 ka (2σ analytical/full uncertainty) indicating eruption only ˜7 ky following the Matuyama‑Brunhes magnetic polarity reversal. Single-crystal incremental heating provides leverage with which to interpret complex populations of 40Ar/39Ar sanidine and U-Pb zircon dates and a substantially improved capability to resolve the timing and causal relationship of events in the geologic record.

  19. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep, E-mail:


    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  20. A novel MAs(III)-selective ArsR transcriptional repressor. (United States)

    Chen, Jian; Nadar, Venkadesh Sarkarai; Rosen, Barry P


    Microbial expression of genes for resistance to heavy metals and metalloids is usually transcriptionally regulated by the toxic ions themselves. Arsenic is a ubiquitous, naturally occurring toxic metalloid widely distributed in soil and groundwater. Microbes biotransform both arsenate (As(V)) and arsenite (As(III)) into more toxic methylated metabolites methylarsenite (MAs(III)) and dimethylarsenite (DMAs(III)). Environmental arsenic is sensed by members of the ArsR/SmtB family. The arsR gene is autoregulated and is typically part of an operon that contains other ars genes involved in arsenic detoxification. To date every identified ArsR is regulated by inorganic As(III). Here we described a novel ArsR from Shewanella putrefaciens selective for MAs(III). SpArsR orthologs control expression of two MAs(III) resistance genes, arsP that encodes the ArsP MAs(III) efflux permease, and arsH encoding the ArsH MAs(III) oxidase. SpArsR has two conserved cysteine residues, Cys101 and Cys102. Mutation of either resulted in loss of MAs(III) binding, indicating that they form an MAs(III) binding site. SpArsR can be converted into an As(III)-responsive repressor by introduction of an additional cysteine that allows for three-coordinate As(III) binding. Our results indicate that SpArsR evolved selectivity for MAs(III) over As(III) in order to control expression of genes for MAs(III) detoxification. © 2017 John Wiley & Sons Ltd.

  1. 40Ar/39Ar geochronology and geochemical reconnaissance of the Eocene Lowland Creek volcanic field, west-central Montana (United States)

    Dudas, F.O.; Ispolatov, V.O.; Harlan, S.S.; Snee, L.W.


    We report geochronological and geochemical data for the calc-alkalic Lowland Creek volcanic field (LCVF) in westcentral Montana. 40Ar/ 39Ar age determinations show that the LCVF was active from 52.9 to 48.6 Ma, with tuff-forming eruptions at 52.9 ?? 0.14 and 51.8 ?? 0.14 Ma. These dates span the age range of vigorous Eocene igneous activity in the Kamloops-Absaroka-Challis belt. The LCVF evolved upward from basal rhyolites (SiO 2>71 wt%) to dacites and andesites (SiO 2 > 62 wt%). Compositional change parallels a transition from early explosive volcanism to late effusive activity. Four geochemical components can be detected in the rocks. A component with 206Pb/204Pb 18.3 and epsilon;Nd>-9 contain a third component; and an andesite with low Nd content and epsilon;Nd near-9 probably contains a fourth component. The first three components probably derive from the lower and middle crust, whereas the fourth is probably from the lithospheric mantle. ?? 2010 by The University of Chicago.

  2. A combined noble gas and {sup 40}Ar-{sup 39}Ar study of Salt Lake Crater xenolith SL322 from Oahu, Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Trieloff, M. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Rocholl, A. [Heidelberg Univ. (Germany). Mineralogisch-Petrographisches Inst.; Jessberger, E.K. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)]|[Muenster Univ. (Germany). Inst. fuer Planetologie


    The microdistribution of noble gases in a garnet pyroxenite nodule from Salt Lake Crater (SLC), Oahu, Hawaii, was investigated by a detailed step-heating and -crushing analysis and a {sup 40}Ar-{sup 39}Ar-study. A noble gas component with MORB type argon, helium and neon resides in CO{sub 2}-rich fluid inclusions trapped in <30 km depth. This component was most probably derived from the nephelinitic SLC host magma and confirms the dominance of MORB type noble gases in the late post-erosional magmatic stages of Hawaiian volcanism, as suggested previsouly (Kurz et al., 1983; Valbracht et al., 1996). A second previously detected (Rocholl et al., 1996) low {sup 40}Ar/{sup 36}Ar ({proportional_to}5000) component turned out to be associated with two different reservoirs. The larger reservoir is most probably related to garnet, the other one is associated with low retentive sites containing few K and Cl and could not yet be adequately identified. The low {sup 40}Ar/{sup 36}Ar ({proportional_to}5000) component hosted by garnet can be interpreted as a mixture of MORB and plume type noble gas components with specific {sup 4}He/{sup 40}Ar ratios. The results demonstrate the complexity of the microdistribution of noble gases in ultramafic nodules and allow insight into plume induced metasomatism of the Hawaiian lithosphere. (orig.)

  3. Investigation of the $^{37}$Ar(n , p) $^{37}\\!$Cl, $^{37}$Ar(n , $\\alpha)^{34}\\!$S and $^{39}$Ar(n , $\\alpha) ^{36}$S reactions at various stellar temperatures

    CERN Document Server

    Goeminne, G; Wagemans, J; Geltenbort, P; Loiselet, M; Gaelens, M; Denecke, B; Köster, U


    A first experimental study of the neutron induced charged particle reactions on $^{37}$Ar and $^{39}$Ar as a function of the neutron energy has been made. Therefore, complementary measurements were performed with thermal neutrons at the High Flux Reactor of the ILL (Grenoble, France) and with resonance neutrons at the GELINA neutron spectrometer of the IRMM (Geel, Belgium). The stellar cross sections, which were calculated from the obtained data, show important discrepancies with the theoretical values used in recent network calculations.

  4. Apūpe pacientiem ar alkohola atkarību


    Romanova, Anastasija


    Bakalaura darba tēma: ”Aprūpe pacientiem ar alkohola atkarību”. Autore izpētīja ar alkoholu atkarīgo pacientu aprūpi un ar to saistīto specifiku ambulatorajā praksē. Bakalaura darbā autore teorētiski analizēja alkohola atkarības medicīniskos aspektus un raksturoja māszinību teoriju saistībā ar aprūpi pacientiem ar alkohola atkarību. Praktiskajā daļā autore izpētīja ar alkoholu atkarīgo pacientu veselības aprūpes specifiku ambulatorajā praksē un noskaidroja ambulatorās aprūpes māsu viedokļus...

  5. On the Availability of ESO Data Papers on arXiv/astro-ph (United States)

    Grothkopf, U.; Bordelon, D.; Meakins, S.; Emsellem, E.


    Using the ESO Telescope Bibliography database telbib, we have investigated the percentage of ESO data papers that were submitted to the arXiv/astro-ph e-print server and that are therefore free to read. Our study revealed an availability of up to 96 % of telbib papers on arXiv over the years 2010 to 2017. We also compared the citation counts of arXiv vs. non-arXiv papers and found that on average, papers submitted to arXiv are cited 2.8 times more often than those not on arXiv. While simulations suggest that these findings are statistically significant, we cannot yet draw firm conclusions as to the main cause of these differences.

  6. Thermal neutron induced (n,p) and (n,α) reactions on 37Ar (United States)

    Bieber, R.; Wagemans, C.; Goeminne, G.; Wagemans, J.; Denecke, B.; Loiselet, M.; Gaelens, M.; Geltenbort, P.; Oberhummer, H.


    The 37Ar(n th,α) 34S and 37Ar(n th,p) 37Cl reactions were studied at the high flux reactor of the ILL in Grenoble. For the 37Ar(n th,α 0) 34S and 37Ar(n th,p) 37Cl reaction cross sections, values of (1070 ± 80) b and (37 ± 4) b, respectively, were obtained. Both values are about a factor 2 smaller than the results of older measurements. The observed suppression of the 37Ar(n th,α 1) 34S transition could be verified from theoretical considerations. Finally, evidence was found for the two-step 37Ar(n th,γα) 34S process.

  7. A high-precision 40Ar/39Ar age for the Nördlinger Ries impact crater, Germany, and implications for the accurate dating of terrestrial impact events (United States)

    Schmieder, Martin; Kennedy, Trudi; Jourdan, Fred; Buchner, Elmar; Reimold, Wolf Uwe


    40Ar/39Ar dating of specimens of moldavite, the formation of which is linked to the Ries impact in southern Germany, with a latest-generation ARGUS VI multi-collector mass spectrometer yielded three fully concordant plateau ages with a weighted mean age of 14.808 ± 0.021 Ma (± 0.038 Ma including all external uncertainties; 2σ; MSWD = 0.40, P = 0.67). This new best-estimate age for the Nördlinger Ries is in general agreement with previous 40Ar/39Ar results for moldavites, but constitutes a significantly improved precision with respect to the formation age of the distal Ries-produced tektites. Separates of impact glass from proximal Ries ejecta (suevite glass from three different surface outcrops) and partially melted feldspar particles from impact melt rock of the SUBO 18 Enkingen drill core failed to produce meaningful ages. These glasses show evidence for excess 40Ar introduction, which may have been incurred during interaction with hydrothermal fluids. Only partially reset 40Ar/39Ar ages could be determined for the feldspathic melt separates from the Enkingen core. The new 40Ar/39Ar results for the Ries impact structure constrain the duration of crater cooling, during the prevailing hydrothermal activity, to locally at least ∼60 kyr. With respect to the dating of terrestrial impact events, this paper briefly discusses a number of potential issues and effects that may be the cause for seemingly precise, but on a kyr-scale inaccurate, impact ages.

  8. The $\\beta$2p -decay mechanism of $^{31}$Ar

    CERN Document Server

    Fynbo, H O U; Axelsson, L; Äystö, J; Bergmann, U C; Fraile-Prieto, L M; Honkanen, J A; Hornshøj, P; Jading, Y; Jokinen, A; Jonson, B; Martel, I; Mukha, I; Nilsson, T; Nyman, G H; Oinonen, M; Piqueras, I; Riisager, K; Siiskonen, T; Smedberg, M H; Tengblad, O; Thaysen, J; Wenander, F


    We have measured the $\\beta$-decay of $^{31}$Ar with a high granularity setup sensitive to multiparticle decay branches. Two-proton emission is observed from the isobaric analog state in $^{31}$Cl to the four lowest states in $^{29}$P and furthermore from a large number of states fed in Gamow-Teller transitions. The mechanism of two-proton emission is studied via energy and angular correlations between the two protons. In all cases the mechanism is found to be sequential yielding information about states in $^{30}$S up to 8 MeV excitation energy. Improved data on the $\\beta$-delayed one-proton branches together with the two-proton data provide precise information about the $\\beta$-strength distribution up to 15 MeV excitation energy. (44 refs).

  9. Vision-Based Object Tracking Algorithm With AR. Drone

    Directory of Open Access Journals (Sweden)

    It Nun Thiang


    Full Text Available This paper presents a simple and effective vision-based algorithm for autonomous object tracking of a low-cost AR.Drone quadrotor for moving ground and flying targets. The Open-CV is used for computer vision to estimate the position of the object considering the environmental lighting effect. This is also an off-board control as the visual tracking and control process are performed in the laptop with the help of Wi-Fi link. The information obtained from vision algorithm is used to control roll angle and pitch angle of the drone in the case using bottom camera and to control yaw angle and altitude of the drone when the front camera is used as vision sensor. The experimental results from real tests are presented.

  10. Mean pion multiplicities in Ar+Sc collisions

    CERN Document Server

    Naskręt, Michał


    Preliminary results for mean negatively charged pion multiplicities $\\langle \\pi^- \\rangle$ using the $h^-$ method are presented for central Ar+Sc collisions at 13, 19, 30, 40, 75 and 150\\textit{A} GeV/c beam momentum. The data were recorded by the NA61/SHINE detector at the CERN SPS. Starting with rapidity distributions ${dn}/{dy}$ the procedure of obtaining total multiplicities is presented. The mean number of wounded nucleons $\\langle W\\rangle$ extracted from the Glissando MC model is used to calculate the ratio $\\langle \\pi^- \\rangle/\\langle W\\rangle.$ The results are compared to those from other experiments and their dependence on colliding systems and collision energy is discussed.

  11. Tracking the timing of subduction and exhumation using 40Ar/39Ar phengite ages in blueschist- and eclogite-facies rocks (Sivrihisar, Turkey) (United States)

    Fornash, Katherine F.; Cosca, Michael A.; Whitney, Donna L.


    Geochronologic studies of high-pressure/low-temperature rocks can be used to determine the timing and rates of burial and exhumation in subduction zones by dating different stages of the pressure–temperature history. In this study, we present new in situ UV laser ablation 40Ar/39Ar phengite ages from a suite of lawsonite blueschist- and eclogite-facies rocks representing different protoliths (metabasalt, metasediment), different structural levels (within and outside of a high-strain zone), and different textural positions (eclogite pod core vs. margin) to understand the timing of these events in an exhumed Neo-Tethyan subduction zone (Sivrihisar Massif, Tavşanlı Zone, Turkey). Weighted mean in situ 40Ar/39Ar ages of phengite from the cores of lawsonite eclogite pods (90–93 Ma) are distinctly older than phengite from retrogressed, epidote eclogite (82 ± 2 Ma). These ages are interpreted as the age of peak and retrograde metamorphism, respectively. Eclogite records the narrowest range of ages (10–14 m.y.) of any rock type analyzed. Transitional eclogite- and blueschist-facies assemblages and glaucophane-rimmed lawsonite + garnet + phengite veins from eclogite pod margins record a much wider age range of 40Ar/39Ar ages (~20 m.y.) with weighted mean ages of ~91 Ma. Blueschists and quartzites record more variable 40Ar/39Ar ages that may in part be related to structural position: samples within a high-strain zone at the tectonic contact of the HP rocks with a meta-ultramafic unit have in situ UV laser ablation 40Ar/39Ar ages of 84.0 ± 1.3–103.7 ± 3.1 Ma, whereas samples outside this zone range to older ages (84.6 ± 2.4–116.7 ± 2.7 Ma) and record a greater age range (22–38 m.y.). The phengite ages can be correlated with the preservation of HP mineral assemblages and fabrics as well as the effects of deformation. Collectively, these results show that high-spatial resolution UV laser ablation 40Ar/39Ar phengite data, when considered

  12. Planktic foraminifer census data from Northwind Ridge cores PI-88-AP P3, PI-88-AR P7 and PI-88-AR P9, Arctic Ocean (United States)

    Foley, Kevin M.; Poore, Richard Z.


    The U.S. Geological Survey recovered 9 piston cores from the Northwind Ridge in the Canada Basin of the Arctic Ocean from a cruise of the USCGC Polar Star during 1988. Preliminary analysis of the cores suggests sediments deposited on Northwind Ridge preserve a detailed record of glacial and interglacial cycles for the last few hundred-thousand to one million years. This report includes quantitative data on foraminifers and selected sediment size-fraction data in 98 samples from Northwind Ridge core PI-88AR P3, 51 samples from core PI-88-AR P7 and 117 samples from core PI-88-AR P9.

  13. Investigation of the 37Ar(n,p)37Cl and 37Ar(n,alpha)34S reactions as a function of the neutron energy


    Wagemans, Cyriel; Goeminne, Gert; Wagemans, Jan; Bieber, Ronald; Loiselet, Marc; Gaelens, Michel; Denecke, Bruno; Geltenbort, Peter; Kolen, Filip


    The energy dependent 37Ar(n,p)37Cl and 37Ar(n,alpha)34S reaction cross sections were determined for the first time in an experimental effort involving three large facilities: the cyclotron of the UCL (Louvain-la-Neuve, Belgium) where implanted 37Ar samples were produced; the high flux reactor of the ILL (Grenoble, France) where thermal (n,p), (n,alpha_0) and (n,alpha_1) cross sections of (37+/-4)b, (1070+/-80)b and (290+/-50)mb respectively could be determined, and the GELINA neutron time-of-...

  14. Tracking the timing of subduction and exhumation using 40Ar/39Ar phengite ages in blueschist- and eclogite-facies rocks (Sivrihisar, Turkey) (United States)

    Fornash, Katherine F.; Cosca, Michael A.; Whitney, Donna L.


    Geochronologic studies of high-pressure/low-temperature rocks can be used to determine the timing and rates of burial and exhumation in subduction zones by dating different stages of the pressure-temperature history. In this study, we present new in situ UV laser ablation 40Ar/39Ar phengite ages from a suite of lawsonite blueschist- and eclogite-facies rocks representing different protoliths (metabasalt, metasediment), different structural levels (within and outside of a high-strain zone), and different textural positions (eclogite pod core vs. margin) to understand the timing of these events in an exhumed Neo-Tethyan subduction zone (Sivrihisar Massif, Tavşanlı Zone, Turkey). Weighted mean in situ 40Ar/39Ar ages of phengite from the cores of lawsonite eclogite pods (90-93 Ma) are distinctly older than phengite from retrogressed, epidote eclogite (82 ± 2 Ma). These ages are interpreted as the age of peak and retrograde metamorphism, respectively. Eclogite records the narrowest range of ages (10-14 m.y.) of any rock type analyzed. Transitional eclogite- and blueschist-facies assemblages and glaucophane-rimmed lawsonite + garnet + phengite veins from eclogite pod margins record a much wider age range of 40Ar/39Ar ages (~20 m.y.) with weighted mean ages of ~91 Ma. Blueschists and quartzites record more variable 40Ar/39Ar ages that may in part be related to structural position: samples within a high-strain zone at the tectonic contact of the HP rocks with a meta-ultramafic unit have in situ UV laser ablation 40Ar/39Ar ages of 84.0 ± 1.3-103.7 ± 3.1 Ma, whereas samples outside this zone range to older ages (84.6 ± 2.4-116.7 ± 2.7 Ma) and record a greater age range (22-38 m.y.). The phengite ages can be correlated with the preservation of HP mineral assemblages and fabrics as well as the effects of deformation. Collectively, these results show that high-spatial resolution UV laser ablation 40Ar/39Ar phengite data, when considered in a petrologic and structural

  15. Estilos de Aprendizagem versus Treinamento Vivencial ao Ar Livre

    Directory of Open Access Journals (Sweden)

    Luciano Munck


    Full Text Available O objetivo deste estudo foi analisar a relação entre estilos individuais de aprendizagem e o treinamento vivencial ao ar livre. Os treinamentos vivenciais tiveram como técnicas o arvorismo, dinâmicas de grupo e paintball. Para alimentar a análise, foram aplicados dois instrumentos de pesquisa a cento e cinco participantes dos treinamentos: o Learning Style Inventory (LSI e um questionário para identificação da satisfação. A coleta de dados foi realizada nos próprios locais de treinamento, sendo a identificação dos estilos de aprendizagem realizada antes, e a da satisfação, depois dos treinamentos. Os dados evidenciaram que o estilo de aprendizagem predominante entre os participantes da pesquisa foi o estilo acomodador(24,8%. A satisfação foi predominantemente alta, com 100% das respostas variando entre mais ou menos satisfeito e muito satisfeito (arvorismo P=0,006. Os dados da pesquisa demonstraram fraca influência dos estilos individuais de aprendizagem na maior ou menor satisfação para com os treinamentos recebidos. Em suma, concluiu-se que os treinamentos vivenciais ao ar livre possuem características que proporcionam alta satisfação para diferentes habilidades e estilos de aprendizagem. Informação essa que deveria ser levada em consideração por gestores e líderes no momento de planejar e estruturar programas de treinamento e desenvolvimento para seus colaboradores.

  16. Resetting of Neoarchaean hornblendes from the Murmansk Terrane (Kola Peninsula, Russia) revealed by a combined 40Ar/39Ar and Rb-Sr analysis (United States)

    de Jong, K.; Timmerman, M. J.; Cliff, R. A.; Wijbrans, J. R.; Daly, J. S.; Balagansky, V. V.


    We present isotope data from amphiboles from the 2.6--2.8 Ga Murmansk Terrane in the northern foreland of the 1.9 Ga Lapland-Kola Orogen of northern Fennoscandia. Most amphiboles are zoned with tschermakitic cores that progressively change to actinolite in 5--10 μm wide areas in rims, defect zones or adjacent to biotite. Biotite chiefly occurs along cleavages, fractures and grain boundaries of amphibole, showing that its hydration and fluid ingress are confined to lattice imperfections. Furnace step heating of hornblende separate MT-11 gave spectra with increasing apparent ages and Ca/K ratios (a proxy for 37ArCa/39Ar_K). Hornblende is intergrown with biotite that also occurs in the matrix. Yet, laser step heating of single hornblende grain MT-11 yielded flat spectra with Neoarchaean apparent ages and constant Ca/K ratios. This suggests that the hornblende grain that was drilled from a thin section and which was not affected by biotite growth retained its Neoarchaean age. In contrast, the hornblende separate with intergrown biotite from this sample has a partially reset Neoarchaean isotope system. Hornblende MT-27 has Neoarchaean apparent ages and lacks low Ca/K ratios in both single grain and mineral separate spectra; it is not affected by biotite growth and this mineral is also absent from the matrix. Age spectra of other hornblende separates have increasing apparent ages to 2.56--2.65 Ga during final 39Ar release; their Ca/K ratio spectra similarly increase. Low Ca/K ratios for gas release below 950^oC imply degassing of included biotite. Apparent ages of the first heating increments may be as young as 1.8 Ga, comparable to the K-Ar and 40Ar/39Ar ages of the youngest biotites. Hornblende-plagioclase pairs from aliquots used for 40Ar/39Ar furnace step heating yielded sharply discordant Rb-Sr ages. MT-11 yielded an 1881 ± 23 Ma Rb-Sr age that compares well with the K-Ar and 40Ar/39Ar ages of biotite in the sample. In contrast, hornblende of sample MT-27 has a

  17. Influence of deformation and fluids on Ar retention in white mica: Dating the Dover Fault, Newfoundland Appalachians (United States)

    Kellett, Dawn A.; Warren, Clare; Larson, Kyle P.; Zwingmann, Horst; van Staal, Cees R.; Rogers, Neil


    White mica 40Ar/39Ar analyses may provide useful constraints on the timing of tectonic processes, but complex geological and thermal histories can perturb Ar systematics in a variety of ways. Ductile shear zones represent excellent case studies for exploring the link(s) between dynamic re-/neo-crystallization of white mica and coeval enhanced fluid flow, and their effect on 40Ar/39Ar dates. White mica 40Ar/39Ar dates were collected from compositionally similar granites that record different episodes of deformation with proximity to the Dover Fault, a terrane-bounding strike-slip shear zone in the Appalachian orogen, Newfoundland, Canada. 40Ar/39Ar data were collected in situ by laser ablation and by step heating single crystals. Results were compared to each other and against complementary U-Pb zircon and monazite, and K-Ar fault gouge analysis. Although step-heat 40Ar/39Ar is a widely applied method in orogenic settings, this dataset shows that relatively flat step-heat 40Ar/39Ar spectra are in contradiction with wide spreads in in-situ40Ar/39Ar dates from the same samples, and that plateau dates in some cases yielded mixed dates of equivocal geological significance. This result indicates that the step-wise release of Ar from white mica likely homogenizes and obscures spatially-controlled Ar isotope reservoirs in white mica from sheared rocks. In contrast, in situ laser ablation 40Ar/39Ar analysis preserves the spatial resolution of 40Ar reservoirs that have been variably reset by deformation and fluid interaction. This study therefore suggests that laser ablation is the best method for dating the timing of deformation recorded by white mica. Final interpretation of results should be guided by microstructural analysis, estimation of deformation temperature, chemical characterization of white mica, and complementary chronometers. Overall the dataset shows that granitic protoliths were emplaced between 430 and 422 Ma (U-Pb zircon). High strain deformation along the

  18. IPCC Fourth Assessment Report (AR4) Observed Climate Change Impacts Database (United States)

    National Aeronautics and Space Administration — The Intergovernmental Panel on Climate Change (IPCC) Fourth Assessement Report (AR4) Observed Climate Change Impacts Database contains observed responses to climate...

  19. The Cerrito Site (AR-4): A Piedra Lumbre Phase Settlement at Abiquiu Reservoir, (United States)


    fragment AR- 513-2- 2c Lepus sp. AR-513-O-3c Capra sp. Lepus sp. Neotoma sp. AR-513-2-c/c Canis familiaris Capra sp. Turkey AR- 513-2-ic i...of the fauna of the Abiquiu Reservoir District: Wildlife which now utilize the area in moderate numbers include mule deer, antelope, cottontail...the mourning doves... Most of the rocky slopes and gravelly banks on the project are too unstable to harbor much wildlife . Cliff swallows and swifts

  20. Acumulación de arsénico en el cultivo de habas (Vicia Faba)


    Francisco Prieto García; Judith Callejas Hernández; Alma D. Román Gutiérrez; Judith Prieto Méndez; Alberto J. Gordillo Martínez; María A. Méndez Marzo


    La presencia de arsénico en aguas y suelos de Zimapán, en el estado de Hidalgo, México, causa que los cultivos de haba presenten concentraciones apreciables de dicho elemento. Los suelos evaluados presentaron texturas, conductividad, contenidos de N y de arsénico diferentes, pero resultados similares en pH, potencial redox, y contenido de materia orgánica. La elevada bioacumulación de arsénico en estos suelos fue directamente proporcional al tiempo de exposición. Las concentraciones de arséni...

  1. Prediction of sub-surface 37Ar concentrations at locations in the Northwestern United States. (United States)

    Fritz, Bradley G; Aalseth, Craig E; Back, Henning O; Hayes, James C; Humble, Paul H; Ivanusa, Pavlo; Mace, Emily K


    The Comprehensive Nuclear-Test-Ban Treaty, which is intended to prevent nuclear weapon test explosions and any other nuclear explosions, includes a verification regime, which provides monitoring to identify potential nuclear explosions. The presence of elevated 37Ar is one way to identify subsurface nuclear explosive testing. However, the naturally occurring formation of 37Ar in the subsurface adds a complicating factor. Prediction of the naturally occurring concentration of 37Ar can help to determine if a measured 37Ar concentration is elevated relative to background. The naturally occurring 37Ar background concentration has been shown to vary between less than 1 mBq/m3 to greater than 100 mBq/m3 (Riedmann and Purtschert, 2011). The purpose of this work was to enhance the understanding of the naturally occurring background concentrations of 37Ar, allowing for better interpretation of results. To that end, we present and evaluate a computationally efficient model for predicting the average concentration of 37Ar at any depth under transient barometric pressures. Further, measurements of 37Ar concentrations in samples collected at multiple locations are provided as validation of the concentration prediction model. The model is shown to compare favorably with concentrations of 37Ar measured at multiple locations in the Northwestern United States. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Friedel-Craft Acylation of ar-Himachalene: Synthesis of Acyl-ar-Himachalene and a New Acyl-Hydroperoxide

    Directory of Open Access Journals (Sweden)

    Abdallah Karim


    Full Text Available Friedel-Craft acylation at 100 °C of 2,5,9,9-tetramethyl-6,7,8,9-tetrahydro-5H-benzocycloheptene [ar-himachalene (1], a sesquiterpenic hydrocarbon obtained by catalytic dehydrogenation of α-, β- and γ-himachalenes, produces a mixture of two compounds: (3,5,5,9-tetramethyl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl-ethanone (2, in 69% yield, with a conserved reactant backbone, and 3, with a different skeleton, in 21% yield. The crystal structure of 3 reveals it to be 1-(8-ethyl-8-hydroperoxy-3,5,5-trimethyl-5,6,7,8-tetrahydronaphthalen-2-yl-ethanone. In this compound O-H…O bonds form dimers. These hydrogen-bonds, in conjunction with weaker C-H…O interactions, form a more extended supramolecular arrangement in the crystal.

  3. A new detrital mica 40Ar/39Ar dating approach for provenance and exhumation of the Eastern Alps (United States)

    Gemignani, L.; Sun, Xilin; Braun, J.; van Gerve, T. D.; Wijbrans, J. R.


    Detrital thermochronology can be used as a tool to quantitatively constrain exhumation rates and its spatial variability from active mountain belts. Commonly used methods for this purpose assume a steady state relationship between tectonic uplift and erosion. However, this assumption does not account for the transitory response of a dynamic orogenic system to changes in the boundary conditions. We propose a different approach that uses the observed detrital age distributions as "markers" of the past exhumation and of the present-day erosion and mixing occurring in a river system. In this paper, we present new 40Ar/39Ar biotite and white mica age distributions for 19 modern river sands from the Eastern Alps north of the Periadriatic line. The results present three main clusters of ages at 0.5-50, 60-120, and 250-350 Ma that record the main orogenic phases in this sector of the Alps. We have applied two numerical methods to the cooling ages to (a) linearly compute the spatial variability of the relative present-day erosion of a set of four detrital mineral samples from drainage basins along the Inn River and (b) quantify the rates of the cooling and erosion in the Tauern Window during Paleocene-Miocene time of the Alpine orogeny. Our results suggest a 0.34-0.84 mm/yr range of exhumation rates for the Tauern Window since the Miocene. Our estimates of exhumation rates of the western Tauern Window are higher than those for the eastern Tauern Window, which is consistent with the previous studies.

  4. Linking Late Pleistocene alpine glacial erosion and continental margin sedimentation: Insights from 40Ar/39Ar dating of silt-sized sediment, Canterbury Basin, New Zealand (United States)

    Villaseñor, Tania; Jaeger, John M.; Foster, David A.


    Quaternary climatic and eustatic cycles in mid-latitude regions have led to more extensive alpine glaciations and continental shelf progradation, respectively. However, the glacial influence on sediment fluxes to the ocean creating continental margin strata is poorly documented. This contribution analyzes the provenance of fine sediment accumulating on the continental shelf during the Late Pleistocene to evaluate the influence of glacial cycles on sediment erosion and routing to the continental shelf. Taking advantage of the contrasting bedrock ages exposed across the Southern Alps, New Zealand, we perform 40Ar/39Ar incremental heating on the bulk silt-size sediment from three drill sites of IODP Expedition 317, Canterbury Basin, New Zealand. The results suggest that a large proportion of sediment accumulating on the continental shelf results from erosion within the Main Divide fault zone of the Southern Alps. Sediment 40Ar/39Ar age fluctuations over this time period suggest that bedrock with various 40Ar/39Ar cooling ages has been differentially eroded in the upper Waitaki River catchment and mixed in the Waitaki-Canterbury sediment-routing system. Across-shelf variations in sediment 40Ar/39Ar age reflect changing modes of sediment dispersal on the continental shelf. Fluvial material, likely derived from the main drainage divide zone, preferentially accumulates in the middle continental shelf, whereas material representing erosion of older bedrock (Torlesse Terrane), located lower in the drainage basin, is dispersed uniformly across the shelf. The age signature of the muddy sediment accumulating on the continental shelf reflects Late Pleistocene landscape evolution of the Southern Alps and its influence on sediment dispersal to the continental shelf.

  5. StAR Enhances Transcription of Genes Encoding the Mitochondrial Proteases Involved in Its Own Degradation (United States)

    Bahat, Assaf; Perlberg, Shira; Melamed-Book, Naomi; Lauria, Ines; Langer, Thomas


    Steroidogenic acute regulatory protein (StAR) is essential for steroid hormone synthesis in the adrenal cortex and the gonads. StAR activity facilitates the supply of cholesterol substrate into the inner mitochondrial membranes where conversion of the sterol to a steroid is catalyzed. Mitochondrial import terminates the cholesterol mobilization activity of StAR and leads to mounting accumulation of StAR in the mitochondrial matrix. Our studies suggest that to prevent mitochondrial impairment, StAR proteolysis is executed by at least 2 mitochondrial proteases, ie, the matrix LON protease and the inner membrane complexes of the metalloproteases AFG3L2 and AFG3L2:SPG7/paraplegin. Gonadotropin administration to prepubertal rats stimulated ovarian follicular development associated with increased expression of the mitochondrial protein quality control system. In addition, enrichment of LON and AFG3L2 is evident in StAR-expressing ovarian cells examined by confocal microscopy. Furthermore, reporter studies of the protease promoters examined in the heterologous cell model suggest that StAR expression stimulates up to a 3.5-fold increase in the protease gene transcription. Such effects are StAR-specific, are independent of StAR activity, and failed to occur upon expression of StAR mutants that do not enter the matrix. Taken together, the results of this study suggest the presence of a novel regulatory loop, whereby acute accumulation of an apparent nuisance protein in the matrix provokes a mitochondria to nucleus signaling that, in turn, activates selected transcription of genes encoding the enrichment of mitochondrial proteases relevant for enhanced clearance of StAR. PMID:24422629

  6. Rutaecarpine and evodiamine selected as β1-AR inhibitor candidates using β1-AR/CMC-offline-UPLC/MS prevent cardiac ischemia-reperfusion injury via energy modulation. (United States)

    Xue, Hui; Cheng, Yongjie; Wang, Xin; Yue, Yuan; Zhang, Weifang; Li, Xiaoni


    In the present study, an offline analytical method combining β1-adrenergic receptor/cell membrane chromatography (β1-AR/CMC) with ultra-performance liquid chromatography/mass spectrometry (UPLC/MS) was used for direct recognition, separation, and identification of β1-AR inhibitors from Evodia rutaecarpa (Juss) Benth, by which rutaecarpine and evodiamine were screened and identified as potential β1-AR antagonists and the β1-AR inhibition activity of them was confirmed by downregulation of cAMP and PKA in vitro test. In addition, the results of in vivo pharmacological trials revealed that rutaecarpine (1.1mg/ml) and evodiamine (1.1mg/ml) attenuated myocardial infarct size injured by myocardial ischemia/reperfusion, improved metabolism disorders between fatty acid and glucose, increased the content of ATP, Ca(2+)-ATPase activity and reduced the content of peroxisome proliferator-activated receptor α (PPARα) protein level. Thus, the β1-AR/CMC-offline-UPLC/MS method developed in this study could be used as an effective alternative for screening β1-AR binding bioactive components in traditional Chinese medicines and the bioactive components could be used to remedy cardiac diseases via energy modulation. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Research on insect pests of tree fruits at the USDA-ARS laboratory in Wapato, WA (United States)

    Tree fruit-related entomological research currently being conducted at the USDA-ARS laboratory in Wapato, WA is reviewed. Scientists at the United States Department of Agriculture, Agricultural Research Service (USDA-ARS) in Wapato, WA conduct research on insect pests of tree fruits and potato. Th...

  8. Effect of Ar bombardment on the electrical and optical properties of ...

    Indian Academy of Sciences (India)

    The influence of low-energy Ar ion beam irradiation on both electrical and optical properties of low-density polyethylene (LDPE) films is presented. The polymer films were bombarded with 320 keV Ar ions with fuences up to 1 × 10 15 cm − 2 . Electrical properties of LDPE films were measured and the effect of ion ...

  9. Applying an AR Technique to Enhance Situated Heritage Learning in a Ubiquitous Learning Environment (United States)

    Chang, Yi Hsing; Liu, Jen-ch'iang


    Since AR can display 3D materials and learner motivation is enhanced in a situated learning environment, this study explores the learning effectiveness of learners when combining AR technology and the situation learning theory. Based on the concept of embedding the characteristics of augmented reality and situated learning into a real situation to…

  10. Model evaluation of RIMPUFF within complex terrain using an 41Ar radiological dataset

    DEFF Research Database (Denmark)

    Dyer, Leisa L.; Astrup, Poul


    The newly updated atmospheric dispersion model RIMPUFF is evaluated using routine releases of 41Ar from the former HIFAR research reactor located in Sydney, Australia. A large number of 41Ar measurements from a network of environmental gamma detectors are used to evaluate the model under a range...

  11. Learning Protein Structure with Peers in an AR-Enhanced Learning Environment (United States)

    Chen, Yu-Chien


    Augmented reality (AR) is an interactive system that allows users to interact with virtual objects and the real world at the same time. The purpose of this dissertation was to explore how AR, as a new visualization tool, that can demonstrate spatial relationships by representing three dimensional objects and animations, facilitates students to…

  12. 75 FR 66306 - Drawbridge Operation Regulation; Arkansas Waterway, Little Rock, AR (United States)


    ..., Little Rock, AR AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: Drawbridge operations for the Baring Cross Railroad Drawbridge across the Arkansas Waterway at Mile 119.6 at Little Rock, Arkansas... (NPRM) entitled Drawbridge Operation Regulation; Arkansas Waterway, Little ] Rock, AR in the Federal...

  13. Error process estimation of arch (1) model corrupted by ar(1) procees

    African Journals Online (AJOL)

    Error process estimation of arch (1) model corrupted by ar(1) procees. D Eni. Abstract. We showed how autocovariance functions can be used to estimate the ARCH(1) process corrupted by AR(I) errors. we performed simulation studies to demonstrate our findings. The studies showed that our model was able to very closely ...

  14. Data of evolutionary structure change: 1AR5A-2NYBC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available cture>H -- cture> ATOM 4062 CA ASN C 78 -36...pdbChain>A 1AR5A KNMAPKGSAPER cture>H ...ain>2NYBC VKNSD-GKLAI >EEE - EEEE...yIDChain>1AR5A VWDPLGKRINT ture>EEE EEEE...pdbChain>C 2NYBC NCLAP--NAGGE

  15. Data of evolutionary structure change: 1AR4B-1UNFX [Confc[Archive

    Lifescience Database Archive (English)


  16. Detection and Classification of Landmines using AR Modeling of GPR Data

    NARCIS (Netherlands)

    Deiana, D.; Anitori, L.


    In this paper we present some results on detection and classification of low metal content anti personnel (AP) landmines using a modified version of the Auto Regressive (AR) modeling algorithm presented in [1,2]. A statistical distance is computed between the AR coefficients of the measured GPR time


    NARCIS (Netherlands)



    We present energy spectra of autoionization electrons resulting from collisions between fully stripped N-15(7+) ions and Ar in the energy range of 1-10 keV amu-1. These spectra have been measured in coincidence with charge-state analysed Ar ions. Observed populations of the various configurations

  18. A Business Case Analysis of the M4/AR-15 Market (United States)


    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA JOINT APPLIED PROJECT A BUSINESS CASE ANALYSIS OF THE M4/AR-15 MARKET By...... market . The market analysis was conducted to fill missing gaps on the M4/AR-15 market size, customer demographics, and supplier base. Data was collected

  19. Research, demonstration, and extension: the ARS area-wide ecologically based invasive plant management project (United States)

    The Area-wide project is a collaborative five year effort funded in 2008 by USDA-ARS that has brought together scientists with the USDA-ARS, universities, land managers, and policy makers throughout the Great Basin. A primary goal of the project is to develop and implement a comprehensive, regional...

  20. Nucleosome exclusion from the interspecies-conserved central AT-rich region of the Ars insulator. (United States)

    Takagi, Haruna; Inai, Yuta; Watanabe, Shun-ichiro; Tatemoto, Sayuri; Yajima, Mamiko; Akasaka, Koji; Yamamoto, Takashi; Sakamoto, Naoaki


    The Ars insulator is a boundary element identified in the upstream region of the arylsulfatase (HpArs) gene in the sea urchin, Hemicentrotus pulcherrimus, and possesses the ability to both block enhancer-promoter communications and protect transgenes from silent chromatin. To understand the molecular mechanism of the Ars insulator, we investigated the correlation between chromatin structure, DNA structure and insulator activity. Nuclease digestion of nuclei isolated from sea urchin embryos revealed the presence of a nuclease-hypersensitive site within the Ars insulator. Analysis of micrococcal nuclease-sensitive sites in the Ars insulator, reconstituted with nucleosomes, showed the exclusion of nucleosomes from the central AT-rich region. Furthermore, the central AT-rich region in naked DNA was sensitive to nucleotide base modification by diethylpyrocarbonate (DEPC). These observations suggest that non-B-DNA structures in the central AT-rich region may inhibit nucleosomal formation, which leads to nuclease hypersensitivity. Furthermore, comparison of nucleotide sequences between the HpArs gene and its ortholog in Strongylocentrotus purpuratus revealed that the central AT-rich region of the Ars insulator is conserved, and this conserved region showed significant enhancer blocking activity. These results suggest that the central AT-rich nucleosome-free region plays an important role in the function of the Ars insulator.

  1. Establishment and Usability Evaluation of an Interactive AR Learning System on Conservation of Fish (United States)

    Lin, Hao-Chiang Koong; Hsieh, Min-Chai; Wang, Cheng-Hung; Sie, Zong-Yuan; Chang, Shei-Hsi


    In this study, we develop an interactive AR Learning System based on Augmented Reality and interactive touch-screen. The learning content knowledge is about conservation of fish in Taiwan. The system combines the game by the concept of AR book which allows children to learn about the importance of conservation of fish. A mechanism is designed to…

  2. Infrared spectroscopy of jet-cooled neutral and ionized aniline-Ar

    NARCIS (Netherlands)

    Piest, H.; von Helden, G.; Meijer, G.


    We report the infrared (IR) absorption spectrum of the jet-cooled neutral aniline-Ar Van der Waals complex together with that of the aniline-Ar cation in the 350-1700 cm(-1) range. The spectra are measured using mass-selective ion detection in two different IR-ultraviolet double-resonance excitation

  3. Conservation of the USDA-ARS National Plant Germplasm System Apple Collection using dormant bud cryopreservation (United States)

    The USDA-ARS National Plant Germplasm System maintains a grafted collection of apple accessions representing 49 taxa in Geneva, NY. Since 1993, dormant buds of many of these accessions have been routinely cryopreserved at the USDA-ARS National Center for Genetic Resources Preservation (NCGRP) in For...

  4. anti-retroviral therapy related liver injury (arli): a series of 11 cases

    African Journals Online (AJOL)


    Dec 2, 2013 ... ANTI-RETROVIRAL THERAPY RELATED LIVER INJURY (ARLI): A SERIES OF 11 CASES. A. E. O. Otedo, MBChB, MMed ... Background: HIV Anti-retroviral therapy (ART) related liver injury (ARLI) is associated with elevated liver .... and the patients were given palliative and supportive care as in-patients; ...

  5. Fremtidens lydværker på Venedig Biennalen og Ars Electronica

    DEFF Research Database (Denmark)

    Vandsø, Anette


    Diskussion af lydkunstens status på baggrund af den aktuelle Lydkunst på Venedig Biennalen og Ars Electronica......Diskussion af lydkunstens status på baggrund af den aktuelle Lydkunst på Venedig Biennalen og Ars Electronica...

  6. CERN inspires 2011 edition of the ARS Electronica Digital Arts Festival

    CERN Multimedia

    Jordan Juras


    This year’s annual ARS Electronica Digital Arts Festival featured CERN as the springboard for its theme, ORIGIN – How it All Begins. The prestigious digital arts festival also served as the perfect venue to launch the Collide@CERN project.   Colours and Lights at the ARS Electronica Digital Arts Festival in Linz (Austria). (Photo by Claudia Marcelloni) The CERN cultural policy project, announced at the beginning of 2011 has started to gain momentum. Ariane Koek, art specialist for the Communication Group, received confirmation in May that ARS Electronica had chosen her proposal to use CERN as the primary source of inspiration for their annual ARS Electronica Festival. This marks the first of the cultural policy’s arts partnerships. The world-renowned celebration for the digital arts is held annually in Linz, Austria, where, amongst the incredible collection of displays and productions, the Prix ARS Electronica – the Oscars of the digital arts world -&...

  7. Presence of arylsulfatase A (ARS A) in multiple sulfatase deficiency disorder fibroblasts. (United States)

    Fluharty, A L; Stevens, R L; Davis, L L; Shapiro, L J; Kihara, H


    Multiple deficiency disorder fibroblasts cultured in MEM-CO2 showed deficiencies of arylsulfatase A(ARS A) comparable to the deficiency in metachromatic leukodystrophy fibroblasts. However, the MSDD fibroblasts cultured in MEM-HEPES contained near normal levels of ARS A. Moreover, the enzyme from the latter fibroblasts was indistinguishable from ARS A of control fibroblasts on DEAE-cellulose chromatography, ratio of activity with several substrates, thermal inactivation, sensitivity to inhibitors, and precipitation by antiserum to human ARS A. These data support the conclusion that the ARS A genome is intact in MSDD fibroblasts and, by extension, in MSDD patients. Other sulfatases were present at levels ranging from mildly deficient to near normal but never as low as seen in the corresponding specific sulfatase deficient disorders.

  8. Studying correlations in 40Ar + 58Fe with FAUST (United States)

    Heilborn, L.; Lawrence, C.; McIntosh, A. B.; Youngs, M. D.; Yennello, S. J.


    The recent detector upgrade of the Forward Array Using Silicon Technology (FAUST) is discussed along with novel implementation of energy, position and particle identification (PID) calibrations which solve challenges introduced by the position-sensitive nature of the new silicon detectors. A slight position-dependence of the energy deposited in the silicon detectors can be accounted for by using corrections derived from a ^{228} Th source calibration. The position will be calibrated by using α particles from a point-like source at the target position through a tungsten mask of precision-cut stripes, which was positioned on the front-plate of the FAUST array. The PID can be calibrated with equations based on the energies deposited in silicon and CsI detectors, which can be verified with the proton-alpha calibration beam used in the experiment. The status and prospects for these calibrations are discussed. Calibration runs and data from the ^{40}{Ar} + {^{58}{Fe}} reaction are shown.

  9. Teaching Children Musical Perception with MUSIC-AR

    Directory of Open Access Journals (Sweden)

    Valéria Farinazzo Martins


    Full Text Available Unfortunately in Brazil there is a non compulsory musical education in schools that leads to loss of sound/musical perception of Brazilian children. This fact, associated with the lack of software for the teaching of musical perception, inspired the creation of Music-AR, a set of software that uses Augmented Reality technology for the teaching of sound properties, such as timbre, pitch and sound intensity. There were four small applications for that: the first one allows the child to manipulate virtual objects linked to sounds, this way, the child can loosen and stretch virtual objects relating them to the (bass and treble sound pitch; the second focus on the concept of sound intensity, associating it to virtual animals been far or near to the children; the third is related to duration of the sound (short or long, and the last is about timbre – the personality of the sound. Tests were applied and the results are presented in this work.

  10. A Study of Compound Solar Eruption in NOAA AR11429 (United States)

    Zhang, Jie; Dhakal, Suman Kumar


    We analyze and report a compound eruption process associated with an M8.4 flare occurred on March 10, 2012 in NOAA AR 11429. In the main phase of the flare, there were two major peaks in GOES X-ray at ~17:20 UT and ~ 17:40 UT respectively. We found that the two flare peaks, separated by about 20 minutes, corresponded to two individual erupting magnetic flux bundles from the same active region and along the same magnetic polarity inversion line. The erupting features were seen as a hot channel-like structure of a temperature of ~ 10 MK in coronal images obtained from SDO AIA 131 A passband. We believe that each erupting feature is originated from an individual magnetic flux bundle. Prior to the onset of the eruption, the magnetic structure of the source region likely contains a double decker configuration, i.e., a coherent flux bundle lies above another coherent flux bundle. The upper bundle became unstable and started to erupt. Shortly after, the lower bundle started to accelerate and merged with the upper bundle, forming a single CME as seen in coronagraph images. This study demonstrates that complex magnetic configuration could form in the corona and result in a compound solar eruption that involves energy release in different magnetic structures. We will discuss the physical processes that inter-connect multiple magnetic structure in an active region.

  11. AR based ornament design system for 3D printing

    Directory of Open Access Journals (Sweden)

    Hiroshi Aoki


    Full Text Available In recent years, 3D printers have become popular as a means of outputting geometries designed on CAD or 3D graphics systems. However, the complex user interfaces of standard 3D software can make it difficult for ordinary consumers to design their own objects. Furthermore, models designed on 3D graphics software often have geometrical problems that make them impossible to output on a 3D printer. We propose a novel AR (augmented reality 3D modeling system with an air-spray like interface. We also propose a new data structure (octet voxel for representing designed models in such a way that the model is guaranteed to be a complete solid. The target shape is based on a regular polyhedron, and the octet voxel representation is suitable for designing geometrical objects having the same symmetries as the base regular polyhedron. Finally, we conducted a user test and confirmed that users can intuitively design their own ornaments in a short time with a simple user interface.

  12. An alternative method for smartphone input using AR markers

    Directory of Open Access Journals (Sweden)

    Yuna Kang


    Full Text Available As smartphones came into wide use recently, it has become increasingly popular not only among young people, but among middle-aged people as well. Most smartphones adopt capacitive full touch screen, so touch commands are made by fingers unlike the PDAs in the past that use touch pens. In this case, a significant portion of the smartphone’s screen is blocked by the finger so it is impossible to see the screens around the finger touching the screen; this causes difficulties in making precise inputs. To solve this problem, this research proposes a method of using simple AR markers to improve the interface of smartphones. A marker is placed in front of the smartphone camera. Then, the camera image of the marker is analyzed to determine the position of the marker as the position of the mouse cursor. This method can enable click, double-click, drag-and-drop used in PCs as well as touch, slide, long-touch-input in smartphones. Through this research, smartphone inputs can be made more precise and simple, and show the possibility of the application of a new concept of smartphone interface.

  13. Students Environmental Awareness of Ar Ridho Nature School Semarang

    Directory of Open Access Journals (Sweden)

    Prihatiningsih Agustina


    Full Text Available In order to meet the goal of environmental education, creating generation who are environmentally concerned and responsible, Ar Ridho Nature School Semarang (SAA, put the message of such education on their gardening subject. The subject has designed for grade 1 to 6 as the school commitment to build a civilization who are able to live in harmony with nature. The purpose of gardening is not only giving students environmental knowledge but also building environmental awareness and skill to preserve nature. Thus, this study aims at presenting environmental awareness among students of SAA and finding out whether there is a relationship between environmental knowledge and environmental awareness. The third grade of students were selected as participants since they were in the middle level of elementary education which has not applied 2013 Curricula (K13. A questionnaire survey was applied to 62 students face to face with considering the level of students for understanding the given questions. Descriptive statistics, ANOVA, and Pearson coefficient of correlation are the techniques used to analyze the data.

  14. Cartografar é traçar um plano comum

    Directory of Open Access Journals (Sweden)

    Virgínia Kastrup


    Full Text Available A pesquisa de campo sobre produção da subjetividade enfrenta o problema de construir conhecimento envolvendo pesquisadores e pesquisados, com territórios e semióticas singulares. Surgem questões relativas ao protagonismo dos participantes e a como traçar com eles um plano comum, garantindo o caráter participativo da pesquisa. No contexto do método da cartografia, o artigo tem como objetivo tratar do tema do comum num duplo aspecto. Num primeiro, discute o acesso ao plano comum. Com base em Gilles Deleuze e Felix Guattari, tal plano não é dito homogêneo nem reúne atores que manteriam entre si relações de identidade, mas opera comunicação entre singularidades, sendo pré-individual e coletivo. Num segundo aspecto, aponta que, enquanto pesquisa-intervenção, a cartografia se compromete com a criação de um mundo comum e heterogêneo. O artigo mostra que o traçado do comum tem como diretriz metodológica a tranversalidade e examina os procedimentos de participação, inclusão e tradução.

  15. Rotational Orientation Effects in NO(X) + Ar Inelastic Collisions. (United States)

    Brouard, M; Chadwick, H; Gordon, S D S; Hornung, B; Nichols, B; Aoiz, F J; Stolte, S


    Rotational angular momentum orientation effects in the rotationally inelastic collisions of NO(X) with Ar have been investigated both experimentally and theoretically at a collision energy of 530 cm(-1). The collision-induced orientation has been determined experimentally using a hexapole electric field to select the ϵ = -1 Λ-doublet level of the NO(X) j = 1/2 initial state. Fully quantum state resolved polarization-dependent differential cross sections were recorded experimentally using a crossed molecular beam apparatus coupled with a (1 + 1') resonance-enhanced multiphoton ionization detection scheme and subsequent velocity-map imaging. To determine the NO sense of rotation, the probe radiation was circularly polarized. Experimental orientation polarization-dependent differential cross sections are compared with those obtained from quantum mechanical scattering calculations and are found to be in good agreement. The origin of the collision-induced orientation has been investigated by means of close-coupled quantum mechanical, quantum mechanical hard shell, quasi-classical trajectory (QCT), and classical hard shell calculations at the same collision energy. Although there is evidence for the operation of limiting classical mechanisms, the rotational orientation cannot be accounted for by QCT calculations and is found to be strongly influenced by quantum mechanical effects.

  16. Dating low-temperature deformation by 40Ar/39Ar on white mica, insights from the Argentera-Mercantour Massif (SW Alps) (United States)

    Sanchez, Guillaume; Rolland, Yann; Schneider, Julie; Corsini, Michel; Oliot, Emilien; Goncalves, Philippe; Verati, Chrystèle; Lardeaux, Jean-Marc; Marquer, Didier


    In order to date low-temperature deformation, intensely strained muscovite porphyroclasts and neocrystallized shear band phengite from greenschist-facies shear zones have been dated by 40Ar/39Ar method in the Argentera-Mercantour massif. Shear zones are featured by gradual mylonitization of a Variscan granite, gneiss and Permian pelite protolith (300-315 Ma) during the Alpine orogenic event. Mineralogical and textural observations indicate that phengites and chlorites developed from biotite and plagioclase in fluid system during deformation following dissolution-transport-precipitation reactions of the type biotite + plagioclase + aqueous fluid = chlorite + albite + phengite + quartz + titanite + K-bearing fluid in the granite-gneiss mylonite. Contrariwise, phengite developed at the expense of clays following substitution reaction in pelite mylonite. Based on conventional thermobarometry on phengite and chlorite and Pressure-Temperature-aqueous fluid (P-T-MH2O) pseudosections calculated with shear zone bulk compositions, the conditions during shear deformation were estimated at 375 ± 30 °C and 4.8-7 ± 1 kbar in an H2O-satured system. In this low temperature environment, 40Ar/39Ar analysis of the Variscan muscovite for various grades of ductile strain intensity shows a limited 40Ar/39Ar isotopic resetting, all ages scattering between 296 and 315 Ma. Under conditions of intense ductile deformation and large-scale fluid circulation, muscovite grains formed during the Variscan retain their much older ages. 40Ar/39Ar dating of very fine grained synkinematic phengite grains, neoformed during the Alpine history, give consistent plateau ages (34-20 Ma) for each shear zone. In detail, 40Ar excess can be detected in the pelite mylonitic sample where phengites crystallized by substitution process while the other mylonitic samples where phengites grow from fluid-induced reactions do not evidence any 40Ar excess. These results demonstrate that the 40Ar/39Ar dating of

  17. Mesozoic rift magmatism in the North Sea region: 40Ar/39Ar geochronology of Scanian basalts and geochemical constraints (United States)

    Bergelin, Ingemar; Obst, Karsten; Söderlund, Ulf; Larsson, Kent; Johansson, Leif


    More than 100 volcanic necks composed of basanites and melanephelinites occur in Scania, southern Sweden, at the junction of two major tectonic lineaments, the Phanerozoic Sorgenfrei-Tornquist Zone (STZ) and the Proterozoic Protogine Zone. New 40Ar/39Ar isotope analyses of whole rock fragments of nine selected basalt necks suggest that the Mesozoic alkaline volcanism in the Scanian province commenced earlier than previously reported and comprised three separate volcanic episodes that span a total period of ca. 80 Myr: a first Jurassic (191-178 Ma), a second at the Jurassic/Cretaceous boundary (ca. 145 Ma), and a final middle Cretaceous episode (ca. 110 Ma). The new results allow for precise time correlations between eruption events in the Scanian and those in the North Sea volcanic provinces. The older, early Jurassic event in Scania is largely synchronous with that in the Egersund Basin and the Forties field whereas the event at ca. 145 Ma is correlated with activity in the Central Graben. These volcanic episodes also correlate in age with Kimmerian tectonic activity. Volcanic activity in the middle Cretaceous period has also been dated in the triple junction in the North Sea and offshore in the Netherland Sector. The correlation of basalt volcanism in Scania with the Egersund nephelinites strongly suggest that volcanism was triggered by repeated tectonic activity along the STZ. Geochemical data of alkaline mafic rocks in the Scanian and the North Sea volcanic provinces imply that different provinces have largely unique geochemical signatures in favour of a heterogeneous mantle in the North Sea volcanic region. However, basalts of different generations in one and the same province cannot be readily separated on the basis of geochemistry, suggesting that the same lithospheric mantle was the source of repeated volcanism over time in each province. The data suggest a low degree of melting of a volatile-bearing mantle lherzolite enriched in incompatible elements with

  18. Geochemistry, 40Ar/39Ar geochronology, and geodynamic implications of Early Cretaceous basalts from the western Qinling orogenic belt, China (United States)

    Zhang, Feifei; Wang, Yuejun; Cawood, Peter A.; Dong, Yunpeng


    The Qinling-Dabie orogenic belt was formed by the collision of the North and South China Cratons during the Early Mesozoic and subsequently developed into an intracontinental tectonic process during late Mesozoic. Field investigations identified the presence of late Mesozoic basalts in the Duofutun and Hongqiang areas in the western Qinling orogenic belt. The petrogenesis of these basalts provides an important constraint on the late Mesozoic geodynamics of the orogen. The representative basaltic samples yield the 40Ar/39Ar plateau age of about 112 Ma. These samples belong to the alkaline series and have SiO2 ranging from 44.98 wt.% to 48.19 wt.%, Na2O + K2O from 3.44 wt% to 5.44 wt%, and MgO from 7.25 wt.% to 12.19 wt.%. They demonstrate the right-sloping chondrite-normalized REE patterns with negligible Eu anomalies (1.00-1.10) and PM-normalized patterns enriched in light rare earth element, large ion lithophile element and high field strength element, similar to those of OIB rocks. These samples additionally show an OIB-like Sr-Nd isotopic signature with εNd(t) values ranging from +6.13 to +10.15 and initial 87Sr/86Sr ratios from 0.7028 to 0.7039, respectively. These samples are geochemically subdivided into two groups. Group 1 is characterized by low Al2O3 and high TiO2 and P2O5 contents, as well as high La/Yb ratios (>20), being the product of the high-pressure garnet fractionation from the OIB-derived magma. Group 2 shows higher Al2O3 but lower P2O5 contents and La/Yb ratios (<20) than Group 1, originating from asthenospheric mantle with input of delaminated lithospheric component. In combination with available data, it is proposed for the petrogenetic model of the Early Cretaceous thickened lithospheric delamination in response to the asthenospheric upwelling along the western Qinling orogenic belt.


    Energy Technology Data Exchange (ETDEWEB)

    Cueto, M.; Herrero, V. J.; Tanarro, I.; Doménech, J. L. [Molecular Physics Department, Instituto de Estructura de la Materia (IEM-CSIC), Serrano 123, E-28006 Madrid (Spain); Cernicharo, J. [Department of Astrophysics, CAB. INTA-CSIC. Crta Torrejón-Ajalvir Km 4, E-28850 Torrejón de Ardoz, Madrid (Spain); Barlow, M. J.; Swinyard, B. M., E-mail: [Department of Physics and Astronomy, University College London. Gower Street, London WC1E 6BT (United Kingdom)


    The protonated argon ion, {sup 36}ArH{sup +}, was recently identified in the Crab Nebula from Herschel spectra. Given the atmospheric opacity at the frequency of its J = 1-0 and J = 2-1 rotational transitions (617.5 and 1234.6 GHz, respectively), and the current lack of appropriate space observatories after the recent end of the Herschel mission, future studies on this molecule will rely on mid-infrared observations. We report on accurate wavenumber measurements of {sup 36}ArH{sup +} and {sup 38}ArH{sup +} rotation-vibration transitions in the v = 1-0 band in the range 4.1-3.7 μm (2450-2715 cm{sup –1}). The wavenumbers of the R(0) transitions of the v = 1-0 band are 2612.50135 ± 0.00033 and 2610.70177 ± 0.00042 cm{sup –1} (±3σ) for {sup 36}ArH{sup +} and {sup 38}ArH{sup +}, respectively. The calculated opacity for a gas thermalized at a temperature of 100 K and with a linewidth of 1 km s{sup –1} of the R(0) line is 1.6 × 10{sup –15} × N({sup 36}ArH{sup +}). For column densities of {sup 36}ArH{sup +} larger than 1 × 10{sup 13} cm{sup –2}, significant absorption by the R(0) line can be expected against bright mid-IR sources.

  20. Hybrid simulation of electron energy distributions and plasma characteristics in pulsed RF CCP sustained in Ar and SiH4/Ar discharges (United States)

    Wang, Xi-Feng; Jia, Wen-Zhu; Song, Yuan-Hong; Zhang, Ying-Ying; Dai, Zhong-Ling; Wang, You-Nian


    Pulsed-discharge plasmas offer great advantages in deposition of silicon-based films due to the fact that they can suppress cluster agglomeration, moderate the energy of bombarding ions, and prolong the species' diffusion time on the substrate. In this work, a one-dimensional fluid/Monte-Carlo hybrid model is applied to study pulse modulated radio-frequency (RF) plasmas sustained in capacitively coupled Ar and SiH4/Ar discharges. First, the electron energy distributions in pulsed Ar and SiH4/Ar plasmas have been investigated and compared under identical discharge-circuit conditions. The electron energy distribution function (EEDF) in Ar discharge exhibits a familiar bi-Maxwellian shape during the power-on phase of the pulse, while a more complex (resembling a multi-Maxwellian) distribution with extra inflection points at lower energies is observed in the case of the SiH4/Ar mixture. These features become more prominent with the increasing fraction of SiH4 in the gas mixture. The difference in the shape of the EEDF (which is pronounced inside the plasma but not in the RF sheath where electron heating occurs) is mainly attributed to the electron-impact excitations of SiH4. During the power-off phase of the pulse, the EEDFs in both Ar and SiH4/Ar discharges evolve into bi-Maxwellian shapes, with shrinking high energy tails. Furthermore, the parameter of ion species in the case of SiH4/Ar discharge is strongly modulated by pulsing. For positive ions, such as SiH3+ and Si2H4+ , the particle fluxes overshoot at the beginning of the power-on interval. Meanwhile, for negative ions such as SiH2- and SiH3- , density profiles observed between the electrodes are saddle-shaped due to the repulsion by the self-bias electric field as it builds up. During the power-off phase, the wall fluxes of SiH2- and SiH3- gradually increase, leading to a significant decrease in the net surface charge density on the driven electrode. Compared with ions, the density of SiH3 is poorly modulated

  1. Polychronous (Early Cretaceous to Palaeogene) emplacement of the Mundwara alkaline complex, Rajasthan, India: 40Ar/39Ar geochronology, petrochemistry and geodynamics (United States)

    Pande, Kanchan; Cucciniello, Ciro; Sheth, Hetu; Vijayan, Anjali; Sharma, Kamal Kant; Purohit, Ritesh; Jagadeesan, K. C.; Shinde, Sapna


    The Mundwara alkaline plutonic complex (Rajasthan, north-western India) is considered a part of the Late Cretaceous-Palaeogene Deccan Traps flood basalt province, based on geochronological data (mainly 40Ar/39Ar, on whole rocks, biotite and hornblende). We have studied the petrology and mineral chemistry of some Mundwara mafic rocks containing mica and amphibole. Geothermobarometry indicates emplacement of the complex at middle to upper crustal levels. We have obtained new 40Ar/39Ar ages of 80-84 Ma on biotite separates from mafic rocks and 102-110 Ma on whole-rock nepheline syenites. There is no evidence for excess 40Ar. The combined results show that some of the constituent intrusions of the Mundwara complex are of Deccan age, but others are older and unrelated to the Deccan Traps. The Mundwara alkaline complex is thus polychronous and similar to many alkaline complexes around the world that show recurrent magmatism, sometimes over hundreds of millions of years. The primary biotite and amphibole in Mundwara mafic rocks indicate hydrous parental magmas, derived from hydrated mantle peridotite at relatively low temperatures, thus ruling out a mantle plume. This hydration and metasomatism of the Rajasthan lithospheric mantle may have occurred during Jurassic subduction under Gondwanaland, or Precambrian subduction events. Low-degree decompression melting of this old, enriched lithospheric mantle, due to periodic diffuse lithospheric extension, gradually built the Mundwara complex from the Early Cretaceous to Palaeogene time.

  2. A carbon cycle science update since IPCC AR-4. (United States)

    Dolman, A J; van der Werf, G R; van der Molen, M K; Ganssen, G; Erisman, J-W; Strengers, B


    We review important advances in our understanding of the global carbon cycle since the publication of the IPCC AR4. We conclude that: the anthropogenic emissions of CO2 due to fossil fuel burning have increased up through 2008 at a rate near to the high end of the IPCC emission scenarios; there are contradictory analyses whether an increase in atmospheric fraction, that might indicate a declining sink strength of ocean and/or land, exists; methane emissions are increasing, possibly through enhanced natural emission from northern wetland, methane emissions from dry plants are negligible; old-growth forest take up more carbon than expected from ecological equilibrium reasoning; tropical forest also take up more carbon than previously thought, however, for the global budget to balance, this would imply a smaller uptake in the northern forest; the exchange fluxes between the atmosphere and ocean are increasingly better understood and bottom up and observation-based top down estimates are getting closer to each other; the North Atlantic and Southern ocean take up less CO2, but it is unclear whether this is part of the 'natural' decadal scale variability; large-scale fires and droughts, for instance in Amazonia, but also at Northern latitudes, have lead to significant decreases in carbon uptake on annual timescales; the extra uptake of CO2 stimulated by increased N-deposition is, from a greenhouse gas forcing perspective, counterbalanced by the related additional N2O emissions; the amount of carbon stored in permafrost areas appears much (two times) larger than previously thought; preservation of existing marine ecosystems could require a CO2 stabilization as low as 450 ppm; Dynamic Vegetation Models show a wide divergence for future carbon trajectories, uncertainty in the process description, lack of understanding of the CO2 fertilization effect and nitrogen-carbon interaction are major uncertainties.

  3. Comparison of Estimation Procedures for Multilevel AR(1 Models

    Directory of Open Access Journals (Sweden)

    Tanja eKrone


    Full Text Available To estimate a time series model for multiple individuals, a multilevel model may be used.In this paper we compare two estimation methods for the autocorrelation in Multilevel AR(1 models, namely Maximum Likelihood Estimation (MLE and Bayesian Markov Chain Monte Carlo.Furthermore, we examine the difference between modeling fixed and random individual parameters.To this end, we perform a simulation study with a fully crossed design, in which we vary the length of the time series (10 or 25, the number of individuals per sample (10 or 25, the mean of the autocorrelation (-0.6 to 0.6 inclusive, in steps of 0.3 and the standard deviation of the autocorrelation (0.25 or 0.40.We found that the random estimators of the population autocorrelation show less bias and higher power, compared to the fixed estimators. As expected, the random estimators profit strongly from a higher number of individuals, while this effect is small for the fixed estimators.The fixed estimators profit slightly more from a higher number of time points than the random estimators.When possible, random estimation is preferred to fixed estimation.The difference between MLE and Bayesian estimation is nearly negligible. The Bayesian estimation shows a smaller bias, but MLE shows a smaller variability (i.e., standard deviation of the parameter estimates.Finally, better results are found for a higher number of individuals and time points, and for a lower individual variability of the autocorrelation. The effect of the size of the autocorrelation differs between outcome measures.

  4. Sexual dimorphism in the glucose homeostasis phenotype of the Aromatase Knockout (ArKO) mice. (United States)

    Van Sinderen, Michelle; Steinberg, Gregory; Jorgensen, Sebastian B; Honeyman, Jane; Chow, Jenny D Y; Simpson, Evan R; Jones, Margaret E E; Boon, Wah Chin


    We investigated the effects of estrogens on glucose homeostasis using the Aromatase Knockout (ArKO) mouse, which is unable to convert androgens into estrogens. The ArKO mouse is a model of total estrogen ablation which develops symptoms of metabolic syndrome. To determine the development and progression of whole body state of insulin resistance of ArKO mice, comprehensive whole body tolerance tests were performed on WT, ArKO and estrogen administrated mice at 3 and 12 months of age. The absence of estrogens in the male ArKO mice leads to hepatic insulin resistance, glucose and pyruvate intolerance from 3 to 12 months with consistent improvement upon estrogen treatment. Estrogen absence in the female ArKO mice leads to glucose intolerance without pyruvate intolerance or insulin resistance. The replacement of estrogens in the female WT and ArKO mice exhibited both insulin sensitizing and resistance effects depending on age and dosage. In conclusion, this study presents information on the sexually dimorphic roles of estrogens on glucose homeostasis regulation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Cerebral artery alpha-1 AR subtypes: high altitude long-term acclimatization responses.

    Directory of Open Access Journals (Sweden)

    Ravi Goyal

    Full Text Available In response to hypoxia and other stress, the sympathetic (adrenergic nervous system regulates arterial contractility and blood flow, partly through differential activities of the alpha1 (α1 - adrenergic receptor (AR subtypes (α1A-, α1B-, and α1D-AR. Thus, we tested the hypothesis that with acclimatization to long-term hypoxia (LTH, contractility of middle cerebral arteries (MCA is regulated by changes in expression and activation of the specific α1-AR subtypes. We conducted experiments in MCA from adult normoxic sheep maintained near sea level (300 m and those exposed to LTH (110 days at 3801 m. Following acclimatization to LTH, ovine MCA showed a 20% reduction (n = 5; P<0.05 in the maximum tension achieved by 10-5 M phenylephrine (PHE. LTH-acclimatized cerebral arteries also demonstrated a statistically significant (P<0.05 inhibition of PHE-induced contractility in the presence of specific α1-AR subtype antagonists. Importantly, compared to normoxic vessels, there was significantly greater (P<0.05 α1B-AR subtype mRNA and protein levels in LTH acclimatized MCA. Also, our results demonstrate that extracellular regulated kinase 1 and 2 (ERK1/2-mediated negative feedback regulation of PHE-induced contractility is modulated by α1B-AR subtype. Overall, in ovine MCA, LTH produces profound effects on α1-AR subtype expression and function.

  6. Characterization of multifarious plant growth promoting traits of rhizobacterial strain AR6 under Chromium (VI) stress. (United States)

    Karthik, Chinnannan; Elangovan, Namasivayam; Kumar, Thamilarasan Senthil; Govindharaju, Subramani; Barathi, Selvaraj; Oves, Mohammad; Arulselvi, Padikasan Indra


    Plant growth promoting rhizobacteria (PGPR) can increase the host plant tolerance to cope up with heavy metal induced stress, which can be improve plant growth. Thus, the present study was designed to isolate Cr(VI) tolerant PGPR strain and evaluate its plant growth promoting (PGP) properties under Cr(VI) stress. Rhizobacterial strain AR6 was isolated from the rhizosphere of Phaseolus vulgaris L. and showed 99% homology with Cellulosimicrobium funkei (KM032184) in BLASTn analysis. Strain AR6 was specifically selected due to its high Cr(VI) tolerance (1200μg/ml) and substantial production of PGP substances. Strain AR6 produced 36.75μg/ml of indole acetic acid (IAA), 60.40μg/ml of ammonia and 14.23μg/ml of exopolysaccharide (EPS). Moreover, strain AR6 showed positive results for catalase, protease, amylase, lipase production and phosphate solubilization. A trend of Cr(VI) concentration dependent progressive decline for PGP traits of strain AR6 was observed excluding EPS which was regularly increased on increasing concentrations of Cr(VI). Among the four tested Cr(VI) concentrations, 250μg/ml showed the maximum toxicity to PGP activities of strain AR6. Inoculation of rhizobacterial strain AR6 significantly increased the root length of test crops in the presence of Cr(VI) and produced a considerable number of colonizes on the root of versatile dicot and monocot plants. Moreover, strain AR6 exhibited strong antagonistic activity against phytopathogen Aspergillus niger. Thus, the present study suggests that metal tolerant and PGP activities of the rhizobacterial strain AR6 could be exploited for environmental and agricultural issues. Copyright © 2017 Elsevier GmbH. All rights reserved.

  7. Phylogenetic analysis of bacterial and archaeal arsC gene sequences suggests an ancient, common origin for arsenate reductase

    Directory of Open Access Journals (Sweden)

    Dugas Sandra L


    Full Text Available Abstract Background The ars gene system provides arsenic resistance for a variety of microorganisms and can be chromosomal or plasmid-borne. The arsC gene, which codes for an arsenate reductase is essential for arsenate resistance and transforms arsenate into arsenite, which is extruded from the cell. A survey of GenBank shows that arsC appears to be phylogenetically widespread both in organisms with known arsenic resistance and those organisms that have been sequenced as part of whole genome projects. Results Phylogenetic analysis of aligned arsC sequences shows broad similarities to the established 16S rRNA phylogeny, with separation of bacterial, archaeal, and subsequently eukaryotic arsC genes. However, inconsistencies between arsC and 16S rRNA are apparent for some taxa. Cyanobacteria and some of the γ-Proteobacteria appear to possess arsC genes that are similar to those of Low GC Gram-positive Bacteria, and other isolated taxa possess arsC genes that would not be expected based on known evolutionary relationships. There is no clear separation of plasmid-borne and chromosomal arsC genes, although a number of the Enterobacteriales (γ-Proteobacteria possess similar plasmid-encoded arsC sequences. Conclusion The overall phylogeny of the arsenate reductases suggests a single, early origin of the arsC gene and subsequent sequence divergence to give the distinct arsC classes that exist today. Discrepancies between 16S rRNA and arsC phylogenies support the role of horizontal gene transfer (HGT in the evolution of arsenate reductases, with a number of instances of HGT early in bacterial arsC evolution. Plasmid-borne arsC genes are not monophyletic suggesting multiple cases of chromosomal-plasmid exchange and subsequent HGT. Overall, arsC phylogeny is complex and is likely the result of a number of evolutionary mechanisms.

  8. Additional /sup 40/Ar-/sup 39/Ar dating of the basement and the alkaline volcanism of Gorringe Bank (Atlantic Ocean)

    Energy Technology Data Exchange (ETDEWEB)

    Feraud, G.; York, D.; Mevel, C.; Cornen, G.; Hall, C.M.; Auzende, J.M.


    /sup 40/Ar//sup 39/Ar step heating analyses are reported for a variety of samples from Gorringe Bank (Atlantic Ocean). Flat age spectra for two primary, igneous hornblendes of Gorringe (corresponding to an age of 143 Ma) show that the K-Ar ages obtained on these samples by Prichard and Mitchell are evidently crystallization and not hybrid ages. This sustains the concept of an initiation age of 140 Ma for Gorringe Bank. No support is found for Carpena's suggestion that the formation of Gorringe Bank began 200 Ma ago. Secondary hornblendes from Ormonde seamount rocks appear to have formed shortly after the initiation of the Bank. Precise plateau ages on samples of two alkaline volcanics from Ormonde correspond to the older limit of the alkaline volcanism suggested by Feraud et al.

  9. Cadomian vs. Variscan evolution of the Ossa-Morena zone (SW Iberia): field and 40Ar/ 39Ar mineral age constraints (United States)

    Dallmeyer, R. D.; Quesada, C.


    Six hornblende and ten muscovite concentrates have been dated from three contrasting tectonic units exposed within the Ossa-Morena zone of the Iberian Massif. These include: (1) the Obejo-Valsequillo domain (north of the Badajoz-Córdoba shear zone); (2) the Sierra Albarrana structural unit (immediately south of the Badajoz-Córdoba shear zone); and (3) the thermal some exposed within the Olivenza-Monesterio antiform (Zafra-Monesterio domain). Hornblende from foliated amphibolite in the Obejo-Valsequillo domain (Siera Negra unit) displays internally discordant 40Ar/ 39Ar age spectra as a result of both intracrystalline contamination with extraneous argon and slight rejuvenation. 36Ar/ 40Ar vs. 39Ar/ 40Ar isotope-correlations are generally well-defined and yield ages of c. 550-560 Ma. These are interpreted to date cooling following late Precambrian-early Paleozoic (Cadomian) tectonothermal activity. This was followed by slight Variscan rejuvenation at c. 375-400 Ma. Muscovite from this unit displays internally discordant age spectra which reflect more extensive Variscan rejuvenation of intracrystalline argon systems which had initially cooled below appropriate blocking temperatures at c. 560 Ma. Hornblende and muscovite from the Sierra Albarrana domain (Sierra Albarrana Group) record 40Ar/ 39Ar plateau and isotope-correlation ages which range between c. 392 Ma and 351 Ma. These results indicate that complete Variscan rejuvenation was followed by relatively rapid post-metamorphic cooling. Hornblende separated from various lithologie elements exposed in the Olivenza-Monesterio Antiform yield variable results. Hornblende within a mafic xenolith in the Monesterio Granodiorite records an isotope-correlation age of c. 553 Ma which is interpreted to date the last cooling through appropriate argon retention temperatures. Hornblende within amphibolite of the Montemolin Series (lower Serie Negra) records internally discordant age spectra which reflect extensive Variscan (c

  10. Tail behavior and OLS based robust inference in AR-GARCH models

    DEFF Research Database (Denmark)

    Lange, T


    The scope of this paper is twofold. We first describe the tail behavior for general AR-GARCH processes and hence extend the results of Basrak, Davis, and Mikosch (2002b) to another empirical relevant model class. Second, and primarily, we study properties for the OLS estimator in general AR-GARCH...... model. Specifically it is shown that the OLS estimator of the autoregressive parameter in the AR-GARCH model has a non-standard limiting distribution with a non-standard rate of convergence when the innovations have non-finite fourth order moment....

  11. On the relationship between atmospheric rivers (ARs) and heavy precipitation over Japan (United States)

    Yatagai, A. I.; Takayabu, Y. N.


    Atmospheric Rivers (ARs) are known as the water-vapor rich part of the broader warm conveyor belt. Recently, several AR detection algorithms are proposed, and structures and that of statistical features are studied globally. Since Japan is a humid country located in the north of the warm pool, ARs, middle tropospheric fast moisture transport, might be an important moisture source for heavy precipitation events in Japan. The purpose of this study is to develop an algorithm of detection of ARs over Japan, and to investigate the possible relationship between them and Japanese heavy precipitation events. Since high spatial correlations were obtained between ERA-Interim reanalysis PW and that of SSM/I (microwave images), we used daily PW (0.75 degree grid) for detection of the ARs. Using 36 years (1979-2014) ERA-Interim, we defined daily smoothed PW climatology. Then, we detected AR area with daily anomaly of PW exceeding 10 mm. However, we exclude round-shaped (caused by Typhoon etc) area and the case of moisture transport not exceeding 30N/30S. The daily AR events over Japan (123-146E, 24-46N) are; 1013 cases for winter (DJF), 1722 for spring (MAM), 2229 for summer (JJA) and 1870 for autumn (SON) during the 36 years. They successfully include Hiroshima disaster event (19 August 2014, Hirota et al., 2015) and Amami heavy precipitation event (20 October 2010). The summer with large AR appearance (1998 and 2010) had negative SOI (La Nina), and lowest appearance year (1992) was the year of El Nino (positively significant SOI). Totally, more ARs come over Japan area in La Nina years, however, the seasonal statistics between SOI and the number of AR is not straightforward, indicating that it is difficult to explain ARs over Japan with only tropical inter-annual variability. We use APHRO-JP (Kamiguchi et al., 2010) daily gridded (0.05 degree) precipitation (1979-2011) over Japanese land areas for comparison. Among the 32 years (1979-2011), we had 82 cases of heavy

  12. Investigation of J → J M1 transitions in 38Ar

    NARCIS (Netherlands)

    Engelbertink, G.A.P.; Lindeman, H.; Jacobs, M.J.N.


    The γ-decay of eight 37Cl(p, γ)38Ar resonances in the range Ep = 1.0–1.8 MeV has been investigated with a 20 cm3 Ge(Li) detector. Precision γ-ray energy measurements yield the energies of 23 bound states of 38Ar (errors 0.14–3.0 keV) and the Q-value of the 37Cl(p, γ)38Ar reaction, Q = 10 242.5±1.1

  13. KioskAR: An Augmented Reality Game as a New Business Model to Present Artworks

    Directory of Open Access Journals (Sweden)

    Yoones A. Sekhavat


    Full Text Available This paper presents the architecture of KioskAR, which is a pervasive game implemented using augmented reality (AR. This game introduces a new business model that makes it possible for players to present their artworks in virtual kiosks using augmented reality, while they are having fun playing the game. In addition to competition between the players in the game, this game requires social interaction between players to earn more points. A user study is conducted to evaluate the sense of presence and the usability of the application. The results of experiments show that KioskAR can achieve a high level of usability as well as sense of presence.

  14. Biodisponibilidad y especiación de arsénico en las algas marinas


    García Sartal, Cristina


    Las algas, desde un punto de vista alimenticio, constituyen una fuente de proteínas, aminoácidos esenciales, vitaminas, lípidos y minerales. Sin embargo, las algas también pueden acumular elementos no esenciales procedentes del agua marina circundante, entre ellos, el arsénico, elemento ampliamente reconocido por su toxicidad. La toxicidad del arsénico depende fundamentalmente de su especiación, resultando más toxicas las especies inorgánicas de arsénico que sus correspondie...

  15. 40Ar/39Ar chronology and volcanology of silicic volcanism in the Davis Mountains, Trans-Pecos Texas (United States)

    Henry, Christopher D.; Kunk, M.J.; McIntosh, W.C.


    Field studies and 40Ar/39Ar dating reveal that silicic volcanism in the Davis Mountains part of the Trans-Pecos Texas volcanic field occurred in six episodes at 0.3 m.y. intervals between 36.8 and 35.3 Ma. Additionally, two groups of silicic intrusions were emplaced at 34.6 and 32.8 Ma. This episodicity is similar to that determined for volcanic fields dominated by ash-flow tuffs, yet voluminous, extensive silicic lavas are considerably more abundant than tuffs in the Davis Mountains, by number of flows and by volume. The preponderance of voluminous silicic lavas over tuffs most likely reflects low water contents and high temperatures of the alkalic and commonly peralkaline Davis Mountains magmas.The earliest episode, at 36.8 Ma, included a widespread and voluminous (possibly >1,000 km3) suite of rhyolite and quartz trachyte lavas, several rhyolite domes, and a strongly rheomorphic, peralkaline ash-flow tuff erupted from a caldera in the northern Davis Mountains. The lava suite extends well beyond the Davis Mountains. Silicic lavas of all episodes probably erupted from widespread, fissure vents. The 36.5 Ma episode consisted of rhyolite to quartz trachyte lavas, also extensive and voluminous (∼200 km3). The 36.3 Ma episode consisted of rhyolite to trachyte tuffs and lavas erupted from a central vent volcano in the southern Davis Mountains. The 35.9 Ma episode consisted of a single, moderately large (∼50 km3) rhyolite lava and a small-volume ash-flow tuff erupted from a caldera in the western Davis Mountains. Rocks emplaced during the 35.6 Ma episode were also rhyolites, including an enigmatic rock that may be strongly rheomorphic ash-flow tuff or a combination of tuff and lava, followed by definite lavas. The 35.3 Ma episode consisted of two ash-flow tuffs, one of which is strongly rheomorphic, and additional voluminous rhyolite lavas (∼120 km3). The rheomorphic tuff erupted from a caldera in the southwestern Davis Mountains. The source of the other tuff is

  16. A high-resolution 40Ar/39Ar lava chronology and edifice construction history for Ruapehu volcano, New Zealand (United States)

    Conway, Chris E.; Leonard, Graham S.; Townsend, Dougal B.; Calvert, Andrew T.; Wilson, Colin J. N.; Gamble, John A.; Eaves, Shaun R.


    Ruapehu is an active 150 km3 andesite-dacite composite volcano located at the southern end of the Taupo Volcanic Zone, New Zealand. The growth of the present-day edifice has occurred throughout coeval eruptive and glacial histories since 200 ka. We present high-precision 40Ar/39Ar eruption ages for 46 samples and whole-rock major element geochemical data for 238 samples from lava flows. These new and existing data are interpreted in the context of geomorphologic and geologic mapping, volcano-ice interaction processes and glacier reconstructions to present an improved chronostratigraphic framework and new edifice evolution history for Ruapehu. Sub-glacial to ice-marginal effusive eruption of medium-K basaltic-andesites and andesites constructed the northern portion of the exposed edifice between 200 and 150 ka, and a wide southeast planèze as well as parts of the northern, eastern and western flanks between 160 and 80 ka. None of the dated lava flows have ages in the range of 80-50 ka, which may reflect an eruptive hiatus. Alternatively the lack of ages may be the result of erosion and burial of lavas and syn-eruptive glacial conveyance of lava flows to the ring-plain during glacial advance at 70-60 ka. From 50-15 ka edifice growth occurred via effusive eruptions onto the glaciated flanks of the volcano, resulting in construction of ice-bounded planèzes and ridges. The distribution of dated ice-marginal lavas indicates a general decrease in glacier thicknesses over this time, except for a short-lived period centred at 31 ka when peak ice cover was reached. The compositional ranges of medium- to high-K andesite and dacite lava flows within 50-35 ka eruptive packages define broadly bimodal high- and low-MgO trends. Lavas erupted at 35-22 ka have compositions that fill a transitional geochemical field between older dacites and younger andesites. Large-scale retreat of flank glaciers since 15 ka has resulted in intra-valley lava flow emplacement at elevations below

  17. Biological and physical controls on O2/Ar, Ar and pCO2 variability at the Western Antarctic Peninsula and in the Drake Passage (United States)

    Eveleth, R.; Cassar, N.; Doney, S. C.; Munro, D. R.; Sweeney, C.


    Using simultaneous sub-kilometer resolution underway measurements of surface O2/Ar, total O2 and pCO2 from annual austral summer surveys in 2012, 2013 and 2014, we explore the impacts of biological and physical processes on the O2 and pCO2 system spatial and interannual variability at the Western Antarctic Peninsula (WAP). In the WAP, mean O2/Ar supersaturation was (7.6±9.1)% and mean pCO2 supersaturation was (-28±22)%. We see substantial spatial variability in O2 and pCO2 including sub-mesoscale/mesoscale variability with decorrelation length scales of 4.5 km, consistent with the regional Rossby radius. This variability is embedded within onshore-offshore gradients. O2 in the LTER grid region is driven primarily by biological processes as seen by the median ratio of the magnitude of biological oxygen (O2/Ar) to physical oxygen (Ar) supersaturation anomalies (%) relative to atmospheric equilibrium (2.6), however physical processes have a more pronounced influence in the southern onshore region of the grid where we see active sea-ice melting. Total O2 measurements should be interpreted with caution in regions of significant sea-ice formation and melt and glacial meltwater input. pCO2 undersaturation predominantly reflects biological processes in the LTER grid. In contrast we compare these results to the Drake Passage where gas supersaturations vary by smaller magnitudes and decorrelate at length scales of 12 km, in line with latitudinal changes in the regional Rossby radius. Here biological processes induce smaller O2/Ar supersaturations (mean (0.14±1.3)%) and pCO2 undersaturations (mean (-2.8±3.9)%) than in the WAP, and pressure changes, bubble and gas exchange fluxes drive stable Ar supersaturations.

  18. High-precision /sup 40/Ar//sup 39/Ar ages of widespread Oligocene ash-flow tuff sheets near Socorro, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Kedzie, L.L.; Sutter, J.F.; Chapin, C.E.


    High-precision /sup 40/Ar//sup 39/Ar age spectrum dating on 5 ash-flow tuff sheets erupted from a group of cauldrons in the Mogollon-Datil volcanic field near Socorro, New Mexico, has produced a precise stratigraphic framework. Previous dating by K-Ar and fission-track methods was not precise enough to distinguish units erupted during a short time (1 million-2 million years), and many K-Ar analyses of cogenetic biotite and Na-sanidine yielded discordant ages. The five units and their high-precision /sup 40/Ar//sup 39/Ar ages, compared to an adopted age of 519.4 Ma for the McClure Mountain hornblende standard (MMhb-1), are listed in ascending stratigraphic order: Hells Mesa Tuff, 32.04 Ma; La Jencia Tuff, 28.76 Ma; Vicks Peak Tuff, 28.46 Ma; Lemitar Tuff, 27.95 Ma; South Canyon Tuff, 27.36 Ma. The temporal resolution for each unit is about 150,000 years. Na-sanidines yield the most concordant age spectra; however, plateau ages of cogenetic sanidine and biotite are equivalent for most samples. Preliminary investigations suggest that the approximately 3.3-million-year hiatus between the Hells Mesa and La Jencia Tuffs may represent a regional lull in volcanic activity. If so, ash-flow tuffs erupted after the hiatus are unlikely to have been derived by differentiation from magmas that produced the underlying volcanic units. Eruption of 4 major ash-flow sheets in 1 million-1.5 million years following the hiatus coincides with the onset of strong, regional extension in the Rio Grande rift and may represent a different magma genesis.

  19. Using high-precision 40Ar/39Ar geochronology to understand volcanic hazards within the Rio Grande rift and along the Jemez lineament, New Mexico (United States)

    Zimmerer, M. J.; McIntosh, W. C.; Heizler, M. T.; Lafferty, J.


    High-precision Ar/Ar ages were generated for late Quaternary volcanic fields in the Rio Grande rift and along the Jemez Lineament, New Mexico, to assess the time-space patterns of volcanism and begin quantifying volcanic hazards for the region. The published chronology of most late Quaternary volcanic centers in the region is not sufficiently precise, accurate, or complete for a comprehensive volcanic hazard assessment. Ar/Ar ages generated as part of this study were determined using the high-sensitivity, multi-collector ARGUS VI mass spectrometer, which provides about an order of magnitude more precise isotopic measurements compared to older generation, single-detector mass spectrometers. Ar/Ar ages suggest an apparent increase in eruption frequency during the late Quaternary within the Raton-Clayton volcanic field, northeastern NM. Only four volcanoes erupted between 426±8 and 97±3 ka. Contrastingly, four volcanoes erupted between 55±2 and 32±5 ka. This last eruptive phase displays a west to east migration of volcanism, has repose periods of 0 to 17 ka, and an average recurrence rate of 1 eruption per 5750 ka. The Zuni-Bandera volcanic field, west-central NM, is composed of the ~100 late Quaternary basaltic vents. Preliminary results suggest that most of the Chain of Craters, the largest and oldest part of the Zuni-Bandera field, erupted between ~100 and 250 ka. Volcanism then migrated to the east, where published ages indicate at least seven eruptions between 50 and 3 ka. Both volcanic fields display a west to east migration of volcanism during the last ~500 ka, although the pattern is more pronounced in the Zuni-Bandera field. A reassessment of low-precision published ages for other late Quaternary volcanic fields in region indicates that most fields display a similar west to east migration of volcanism during the last ~500 ka. One possible mechanism to explain the observed patterns of volcanism is the westward migration of the North American plate relative

  20. 31Ar and 27S: Beta-delayed two-proton emission and mass excess (United States)

    Borrel, V.; Jacmart, J. C.; Pougheon, F.; Anne, R.; Detraz, C.; Guillemaud-Mueller, D.; Mueller, A. C.; Bazin, D.; Del Moral, R.; Dufour, J. P.; Hubert, F.; Pravikoff, M. S.; Roeckl, E.


    Beta-delayed two-proton decay is reported for the T z = - {5}/{2} isotopes 31Ar and 27S wnich were produced by fragmentation of 36Ar at 85 MeV/u. The two-proton nature of this decay is established on the basis of the number of events which trigger two detectors or more in a silicon-detector telescope. The proton energy spectra give experimental values for the daughter energy levels and for the branching ratios. The deduced values of the 31Ar and 27S masses are discussed and compared with mass predictions. For both nuclei, other channels like β3p and βpα are to be searched for since the observed β2p and βp branches do not fully account for the total decay width of the isobaric analog states in the daughter nuclei. Partial decay schemes are proposed for 31Ar and 27S.

  1. Downregulated StAR gene and male reproductive dysfunction caused by nifedipine and ethosuximide

    Directory of Open Access Journals (Sweden)

    Rasha A. Ebiya


    Conclusions: Both nifedipine and ethosuximide significantly increase chromosome abnormalities, decrease sperm function, and down regulate StAR-mRNA expression. All these side effects may lead to irreversible male sterility.

  2. Estimation and asymptotic inference in the first order AR-ARCH model

    DEFF Research Database (Denmark)

    Lange, Theis; Rahbek, Anders; Jensen, Søren Tolver


    This article studies asymptotic properties of the quasi-maximum likelihood estimator (QMLE) for the parameters in the autoregressive (AR) model with autoregressive conditional heteroskedastic (ARCH) errors. A modified QMLE (MQMLE) is also studied. This estimator is based on truncation of individu...... for the QMLE to be asymptotically normal. Finally, geometric ergodicity for AR-ARCH processes is shown to hold under mild and classic conditions on the AR and ARCH processes.......This article studies asymptotic properties of the quasi-maximum likelihood estimator (QMLE) for the parameters in the autoregressive (AR) model with autoregressive conditional heteroskedastic (ARCH) errors. A modified QMLE (MQMLE) is also studied. This estimator is based on truncation of individual...

  3. Electric Modulus Studies of Low Energy Ar9+ Irradiated Conducting Polymer PANI-PVA (United States)

    Himanshu, A. K.; Bandyopadhyay, S. K.; Sen, Pintu; Sinha, T. P.


    Polyaniline (PANI) prepared using water soluble support polymer polyvinyl alcohol (PVA) was subjected to irradiation with 150 keV Argon (Ar9+) ion at the fluence of 7.68×1014 ion/cm2 with beam current of 2 μA (electrical). There has been implantation of Ar atoms. The field dependence of electric modulus response has been measured in a frequency range from 100 Hz to 1 MHz and in a temperature range from room temperature to the glass transition. Ar9+ implantation in PANI-PVA shifts the peak maximum to the lower frequency. Resistivity analysis earlier showed a decrease in the localization length as well as increase in the energy gap due to the scission of bonds by the energy deposited by Ar9+ ions.

  4. Degradation Assessment and Fault Diagnosis for Roller Bearing Based on AR Model and Fuzzy Cluster Analysis

    Directory of Open Access Journals (Sweden)

    Lingli Jiang


    Full Text Available This paper proposes a new approach combining autoregressive (AR model and fuzzy cluster analysis for bearing fault diagnosis and degradation assessment. AR model is an effective approach to extract the fault feature, and is generally applied to stationary signals. However, the fault vibration signals of a roller bearing are non-stationary and non-Gaussian. Aiming at this problem, the set of parameters of the AR model is estimated based on higher-order cumulants. Consequently, the AR parameters are taken as the feature vectors, and fuzzy cluster analysis is applied to perform classification and pattern recognition. Experiments analysis results show that the proposed method can be used to identify various types and severities of fault bearings. This study is significant for non-stationary and non-Gaussian signal analysis, fault diagnosis and degradation assessment.

  5. GPM Ground Validation USDA ARS Soil Moisture IFloodS V1 (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation United States Department of Agriculture (USDA) Agricultural Research Service (ARS) Soil Moisture IFloodS dataset was collected during the...

  6. 77 FR 51064 - Huntington Foam LLC, Fort Smith, AR; Notice of Affirmative Determination Regarding Application... (United States)


    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Huntington Foam LLC, Fort Smith, AR; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated May 21, 2012, the State Workforce...

  7. IPCC Fifth Assessment Report (AR5) Observed Climate Change Impacts Database, Version 2.01 (United States)

    National Aeronautics and Space Administration — The Intergovernmental Panel on Climate Change Fifth Assessment Report (AR5) Observed Climate Change Impacts Database, Version 2.01 contains observed responses to...

  8. 78 FR 5202 - Notice of Inventory Completion: Arkansas State University Museum, Jonesboro, AR (United States)


    ... National Park Service Notice of Inventory Completion: Arkansas State University Museum, Jonesboro, AR AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Arkansas State University Museum... culturally affiliated with the human remains may contact the Arkansas State University Museum. Repatriation...

  9. 78 FR 5199 - Notice of Inventory Completion: Arkansas State University Museum, Jonesboro, AR (United States)


    ... National Park Service Notice of Inventory Completion: Arkansas State University Museum, Jonesboro, AR AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Arkansas State University Museum... associated funerary objects may contact the Arkansas State University Museum. Repatriation of the human...

  10. USDA-ARS Riesel Watersheds, Riesel, Texas, USA: Water quality research database

    National Research Council Canada - National Science Library

    R Daren Harmel; Richard L Haney; Douglas R Smith; Michael White; Kevin W King


    ... ( In addition, water quality data including dissolved inorganic N and P compounds measured from more than 1000 storm runoff events, 1300 base flow sampling events...

  11. USDA‐ARS Riesel Watersheds, Riesel, Texas, USA: Water quality research database

    National Research Council Canada - National Science Library

    Harmel, R. Daren; Haney, Richard L; Smith, Douglas R; White, Michael; King, Kevin W


    ... ( ). In addition, water quality data including dissolved inorganic N and P compounds measured from more than 1000 storm runoff events, 1300 base flow sampling events...

  12. Teoria Construtal e desempenho térmico de Trocadores de Calor Solo-Ar


    Ruth da Silva Brum


    Trocadores de Calor Solo-Ar (TCSA) são dispositivos usados para melhorar o condicionamento térmico de ambientes construídos. Eles funcionam através da ventilação do ar por um ou mais dutos enterrados, utilizando o solo como fonte ou sumidouro de calor. Em virtude da defasagem entre as temperaturas do ar e das camadas superficiais da Terra, é possível resfriar o ar no verão e aquecê-lo no inverno. Seus princípios de operação baseiam-se na mecânica dos fluidos e transferência de calor, áreas on...

  13. Population pharmacokinetics of ticagrelor and AR-C124910XX in patients with prior myocardial infarction
. (United States)

    Röshammar, Daniel; Bergstrand, Martin; Andersson, Tomas; Storey, Robert F; Hamrén, Bengt


    The population pharmacokinetics of ticagrelor and its active metabolite AR-C124910XX were characterized following ticagrelor 60 mg or 90 mg twice daily oral long-term treatment in 4,426 patients with a history of myocardial infarction. The ticagrelor and AR-C124910XX plasma concentration-time data were described by one-compartment models with first-order absorption or metabolite formation and elimination. Systemic exposure to ticagrelor and AR-C124910XX were stable over time. Ticagrelor apparent clearance (CL/F) was 17 L/h for the 60-mg and 15.4 L/h for the 90-mg dose. The CL/F of AR-C124910XX was 11.1 L/h for the 60-mg and 9.95 L/h for the 90-mg dose. Both ticagrelor and AR-C124910XX CL/F were independently influenced by body weight, sex, age, smoking, and Japanese ethnicity. Female sex and age > 75 years were the only categorical covariates, having more than 20% effect on AR-C124910XX CL/F. Ticagrelor CL/F was 6% higher and 11% lower, whereas AR-C124910XX CL/F was 26% higher and 34% lower for patients weighing 110 and 50 kg, respectively, compared with an 83 kg patient. The small differences in exposure to both ticagrelor and AR-C124910XX between demographic subgroups were in accordance with the consistent efficacy and safety outcomes observed across the population. The results were similar to those observed previously in patients with acute coronary syndromes.

  14. Rapid change of multiplicity fluctuations in system size dependence at SPS energies arXiv

    CERN Document Server

    Recent preliminary results on multiplicity fluctuations in p+p, Be+Be and Ar+Sc collisions from the NA61/SHINE collaboration are presented. The scaled variance of charged hadron multiplicity changes little when going from p+p to Be+Be collisions and drops dramatically from Be+Be to Ar+Sc interactions. The centrality selection procedure and the influence of volume fluctuations are discussed. Comparisons with the EPOS event generator are shown.

  15. AR Variant ARv567es Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Gang Liu


    Full Text Available Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly marked by progression to castration-resistant prostate cancer (CRPC after a period of regression. Continued activation of androgen receptor (AR signaling is attributed as one of the most important mechanisms underlying failure of therapy. Recently, the discovery of constitutively active AR splice variants (AR-Vs adds more credence to this idea. Expression of AR-Vs in metastases portends a rapid progression of the tumor. However, the precise role of the AR-Vs in CRPC still remains unknown. ARv567es is one of the two AR variants frequently found in human CRPC xenografts and metastases. Herein, we developed a probasin (Pb promoter-driven ARv567es transgenic mouse, Pb-ARv567es, to evaluate the role of ARv567es in both autonomous prostate growth and progression to CRPC. We found that expression of ARv567es in the prostate results in epithelial hyperplasia by 16 weeks and invasive adenocarcinoma is evident by 1 year of age. The underlying genetic cellular events involved a cell cycle-related transcriptome and differential expression of a spectrum of genes that are critical for tumor initiation and progression. These findings indicate that ARv567es could induce tumorigenesis de novo and signifies the critical role of AR-Vs in CRPC. Thus, the Pb-ARv567es mouse could provide a novel model in which the role of AR variants in prostate cancer progression can be examined.

  16. The science case for 37Ar as a monitor for underground nuclear explosions

    Energy Technology Data Exchange (ETDEWEB)

    Haas, Derek A.; Orrell, John L.; Bowyer, Ted W.; McIntyre, Justin I.; Miley, Harry S.; Aalseth, Craig E.; Hayes, James C.


    A new calculation of the production of 37Ar from nuclear explosion neutron interactions on 40Ca in a suite of common sub-surface materials (rock, etc) is presented. Even in mineral structures that are relatively low in Ca, the resulting 37Ar signature is large enough for detection in cases of venting or gaseous diffusion driven by barometric pumping. Field and laboratory detection strategies and projected sensitivities are presented.

  17. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance


    Chen, Xinfeng; Li, Haohong


    Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform) that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface) applicatio...

  18. MetaMath and MathGeAr Projects: Students' Perceptions of Mathematics in Engineering Education


    Lealdino, Pedro,; Mercat, Christian; El-Demerdash, Mohamed


    International audience; This research aims at studying engineering students’ perceptions of their mathematics courses. We present the methodology of data collection, the main themes that the questionnaire investigates and the results. The population on which we base this study are partners in two Tempus projects, MetaMath in Russia and MathGeAr in Georgia and Armenia. Pedro Lealdino Filho, Christian Mercat, Mohamed El-Demerdash. MetaMath and MathGeAr Projects: Students’ perceptions of mathema...

  19. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance

    Directory of Open Access Journals (Sweden)

    Xinfeng Chen


    Full Text Available Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms. We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

  20. Immersive realities: articulating the shift from VR to mobile AR through artistic practice (United States)

    Margolis, Todd; Cornish, Tracy; Berry, Rodney; DeFanti, Thomas A.


    Our contemporary imaginings of technological engagement with digital environments has transitioned from flying through Virtual Reality to mobile interactions with the physical world through personal media devices. Experiences technologically mediated through social interactivity within physical environments are now being preferenced over isolated environments such as CAVEs or HMDs. Examples of this trend can be seen in early tele-collaborative artworks which strove to use advanced networking to join multiple participants in shared virtual environments. Recent developments in mobile AR allow untethered access to such shared realities in places far removed from labs and home entertainment environments, and without the bulky and expensive technologies attached to our bodies that accompany most VR. This paper addresses the emerging trend favoring socially immersive artworks via mobile Augmented Reality rather than sensorially immersive Virtual Reality installations. With particular focus on AR as a mobile, locative technology, we will discuss how concepts of immersion and interactivity are evolving with this new medium. Immersion in context of mobile AR can be redefined to describe socially interactive experiences. Having distinctly different sensory, spatial and situational properties, mobile AR offers a new form for remixing elements from traditional virtual reality with physically based social experiences. This type of immersion offers a wide array of potential for mobile AR art forms. We are beginning to see examples of how artists can use mobile AR to create social immersive and interactive experiences.

  1. Postcollision interactions in the Auger decay of the Ar L-shell

    Energy Technology Data Exchange (ETDEWEB)

    Samson, J.A.R.; Stolte, W.C.; He, Z.X. [Univ. of Nebraska, Lincoln, NE (United States)] [and others


    The photoionization cross sections for Ar{sup +} through Ar{sup 4+}, produced by the Auger decay of an inner shell 2p hole, have been measured between 242 eV and 253 eV on beamline 9.0.1 and 6.3.2. In this study the authors are interested in near threshold phenomenon involving postcollision interactions (PCI), which are related to the Auger decay of a vacancy in the Ar L-shell. During an Auger decay a postcollision interaction can occur causing the out-going photoelectron to be retarded thus losing a certain amount of energy. If the retardation is sufficiently large the photoelectron will not escape. This result produces a singly charged ion, which normally would not be present. Such evidence of electron capture by the PCI effect was first shown clearly by Eberhardt et al. and, with higher resolution, in the present work. However, capture of the photoelectron is expected to be 100% exactly at the L{sub 2,3} thresholds. Thus, from the authors results they would have expected the Ar{sup 2+} signal to be zero at threshold, but it was not? The authors can explain this anomoly on the basis that during the Auger decay the photoelectrons are captured into high lying excited states of Ar{sup +}, which subsequently decay through autoionization yielding Ar{sup 2+}. Future work in this area will seek experimental evidence to verify this prediction.

  2. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance. (United States)

    Chen, Xinfeng; Li, Haohong


    Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform) that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface) application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition) function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms). We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

  3. Use of 41Ar production to measure ablator areal density in NIF beryllium implosions (United States)

    Wilson, D. C.; Cassata, W. S.; Sepke, S. M.; Velsko, C. A.; Huang, H.; Yeamans, C. B.; Kline, J. L.; Yi, A.; Simakov, A. N.; Haan, S. W.; Batha, S. H.; Dewald, E. L.; Rygg, J. R.; Tommasini, R.; Xu, H.; Kong, C.; Bae, J.; Rice, N.


    For the first time, 41Ar produced by the (n,ϒ) reaction from 40Ar in the beryllium shell of a DT filled Inertial Confinement Fusion capsule has been measured. Ar is co-deposited with beryllium in the sputter deposition of the capsule shell. Combined with a measurement of the neutron yield, the radioactive 41Ar then quantifies the areal density of beryllium during the DT neutron production. The measured 1.15 ± 0.17 × 10+8 atoms of 41Ar are 2.5 times that from the best post-shot calculation, suggesting that the Ar and Be areal densities are correspondingly higher than those calculated. Possible explanations are that (1) the beryllium shell is compressed more than calculated, (2) beryllium has mixed into the cold DT ice, or more likely (3) less beryllium is ablated than calculated. Since only one DT filled beryllium capsule has been fielded at NIF, these results can be confirmed and expanded in the future.

  4. Using ICD for structural analysis of clusters: a case study on NeAr clusters (United States)

    Fasshauer, E.; Förstel, M.; Pallmann, S.; Pernpointner, M.; Hergenhahn, U.


    We present a method to utilize interatomic Coulombic decay (ICD) to retrieve information about the mean geometric structures of heteronuclear clusters. It is based on observation and modelling of competing ICD channels, which involve the same initial vacancy, but energetically different final states with vacancies in different components of the cluster. Using binary rare gas clusters of Ne and Ar as an example, we measure the relative intensity of ICD into (Ne+)2 and Ne+Ar+ final states with spectroscopically well separated ICD peaks. We compare in detail the experimental ratios of the Ne-Ne and Ne-Ar ICD contributions and their positions and widths to values calculated for a diverse set of possible structures. We conclude that NeAr clusters exhibit a core-shell structure with an argon core surrounded by complete neon shells and, possibly, further an incomplete shell of neon atoms for the experimental conditions investigated. Our analysis allows one to differentiate between clusters of similar size and stochiometric Ar content, but different internal structure. We find evidence for ICD of Ne 2s-1, producing Ar+ vacancies in the second coordination shell of the initial site.

  5. Ar-rahnu as a Source of Financial Sustainability for Women Micro-Entrepreneurs in Malaysia

    Directory of Open Access Journals (Sweden)

    Nik Hadiyan Nik Azman


    Full Text Available Muslims in Malaysia had practiced ar-rahnu for fulfilling their financial need, especially for emergency purposes since early 1990s. The pioneer of ar-rahnu in Malaysia is Muassasah Gadaian Islam Terengganu (MGIT in January 1992, followed by the Kelantan Capitalization Berhad (PKB in March 1992. Both of these Islamic pawn centres are among the earliest exponents to the Islamic pawn scheme in Malaysia. Ar-rahnu is an increasingly popular financing option among micro-entrepreneurs in Malaysia, particularly women micro-entrepreneurs. Women micro-entrepreneurs play a vital role in the Malaysian economy and could be considered as the backbone of the industrial development in Malaysia. This study examines the role of ar-rahnu as a source of financial stability for women micro-entrepreneurs. 600 questionnaires were distributed at three states in Malaysia which are Kelantan, Terengganu and Kedah. Then, this study used SPSS and SEM Amos to analyses the data for 600 respondents (women micro-entrepreneurs in Malaysia. In essence, this study finds that shariah compliancy, locality, service charges, collateral and customer satisfaction has positive and significant impact towards the use of ar-rahnu. The study also found use of ar-rahnu has significant impact towards financial self-sufficiency for women micro-entrepreneurs.

  6. Pre-Himalayan tectono-magmatic imprints in the Darjeeling-Sikkim Himalaya (DSH) constrained by 40Ar/39Ar dating of muscovite (United States)

    Acharyya, Subhrangsu K.; Ghosh, Subhajit; Mandal, Nibir; Bose, Santanu; Pande, Kanchan


    The Lower Lesser Himalayan Sequence (L-LHS) in Darjeeling-Sikkim Himalaya (DSH) displays intensely deformed, low-grade meta-sedimentary rocks, frequently intervened by granite intrusives of varied scales. The principal motivation of our present study is to constrain the timing of this granitic event. Using 40Ar/39Ar geochronology, we dated muscovite from pegmatites emplaced along the earliest fabric in the low grade Daling phyllite, and obtained ∼1850 Ma Ar-Ar muscovite cooling age, which is broadly coeval with crystallization ages of Lingtse granite protolith (e.g., 1800-1850 Ma U-Pb zircon ages) reported from the L-LHS. We present here field observations to show the imprints (tectonic fabrics) of multiple ductile deformation episodes in the LHS terrain. The earliest penetrative fabric, axial planar to N-S trending reclined folds, suggest a regional tectonic event in the DSH prior to the active phase of Indo-Asia collision. Based on the age of granitic bodies and their structural correlation with the earliest fabric, we propose that the L-LHS as a distinct convergent tectono-magmatic belt, delineating the northern margin of Indian craton in the framework of the ∼1850 Ma Columbia supercontinent assembly.

  7. Inelastic processes in Na$^{+}-$Ne, Ar and Ne$^{+},$ Ar$^{+}-$Na collisions in energy range $0.5-14$ keV

    CERN Document Server

    Lomsadze, R A; Kezerashvili, R Ya


    Absolute cross sections for charge-exchange, ionization and excitation in Na$% ^{+}-$Ne and Na$^{+}-$Ar collisions were measured in the ion energy range $% 0.5-10$ keV using a refined version of a capacitor method, and collision and optical spectroscopy methods simultaneously in the same experimental set-up. Ionization cross sections for Ne$^{+}-$Na and Ar$^{+}-$Na collisions are measured at the energies of $2-14$ keV using a crossed-beam spectroscopy method. The experimental data and the schematic correlation diagrams are used to analyze and determine the mechanisms for these processes. For the charge-exchange process in Na$^{+}$ $-$Ar collisions two nonadiabatic regions are revealed and mechanisms responsible for these regions are explained. Structural peculiarity on the excitation function for the resonance lines of argon atoms in Na$^{+}$ $-$Ar collisions are observed and the possible mechanisms of this phenomenon are explored. The measured ionization cross sections for Na$^{+}-$Ne and Ne$^{+}-$Na collisi...

  8. The Interaction of Child-Parent Shared Reading with an Augmented Reality (AR) Picture Book and Parents' Conceptions of AR Learning (United States)

    Cheng, Kun-Hung; Tsai, Chin-Chung


    Following a previous study (Cheng & Tsai, 2014. "Computers & Education"), this study aimed to probe the interaction of child-parent shared reading with the augmented reality (AR) picture book in more depth. A series of sequential analyses were thus conducted to infer the behavioral transition diagrams and visualize the continuity…

  9. The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Weihong; Xu, Bin; Yao, Yiting; Yu, Xiaoling [Department of Clinical Laboratory, Tongren Hospital, Shanghai (China); Shen, Jie, E-mail: [Department of Administrative, Tongren Hospital, No. 786 Yuyuan Road, Changning District, Shanghai (China)


    In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide production, exerted potent anti-proliferative and pro-apoptotic activities in established (SW-620 and HCT-116 lines) and primary human colon cancer cells. Exogenously-added sphingosine 1-phosphate (S1P) suppressed AR-42-induced activity, yet a cell-permeable ceramide (C4) facilitated AR-42-induced cytotoxicity against colon cancer cells. In addition, AR-42-induced ceramide production and anti-colon cancer cell activity were inhibited by the ceramide synthase inhibitor fumonisin B1, but were exacerbated by PDMP, which is a ceramide glucosylation inhibitor. In vivo, oral administration of a single dose of AR-42 dramatically inhibited SW-620 xenograft growth in severe combined immunodeficient (SCID) mice, without inducing overt toxicities. Together, these results show that AR-42 dramatically inhibits colon cancer cell proliferation in vitro and in vivo, and ceramide production might be the key mechanism responsible for its actions. - Highlights: • AR-42 is anti-proliferative against primary/established colon cancer cells. • AR-42 induces significant apoptotic death in primary/established colon cancer cells. • Ceramide production mediates AR-42-induced cytotoxicity in colon cancer cells. • AR-42 oral administration potently inhibits SW-620 xenograft growth in SCID mice.

  10. Geological significance of ^{40}Ar/^{39}Ar mica dates across a mid-crustal continental plate margin and implications for the evolution of lithospheric collisions (United States)

    Friedrich, Anke; Hodges, Kip


    The Connemara region of the Irish Caledonides is a world-class example of a regional-scale high-temperature metamorphic terrain. Its formation relates to calkalkaline magmatism in a double-vergent island arc-continent collisional setting, for which a protracted evolution was inferred based on a > 75 Ma spread in U-Pb, Rb-Sr, and K-Ar mineral ages. Such a history is inconsistent with geological field observations, which imply a simple relationship between syntectonic magmatism, deformation and Barrovian-type metamorphism. Here, we explore the significance of the large spread in apparent cooling ages using 40Ar/39Ar mica thermochronometers of varying grain sizes and composition, which we collected across all metamorphic grades. We integrated geological and previously published geochronological evidence to identify a 32 Ma range (ca. 475 to 443 Ma) of permissible cooling ages and distinguished them from those dates not related to cooling after high-temperature metamorphism. Variations in 40Ar/39Ar dates at a single locality are ≤ 10 Ma, implying rapid cooling (≥ 6 to 26˚ C/Ma) following metamorphism and deformation. A distinct cooling age variation (≥ 15 Ma) occurs on the regional-scale, consistent with spatial differences in the metamorphic, magmatic, and deformational evolution across the Connemara region. This cooling record relates to a lateral thermal and strain-rate gradient in an evolving arc-continent collision, rather than to differential unroofing of the orogen. Our results imply that the large (≥ 50 Ma) spread in thermochronometers commonly observed in orogens does not automatically translate into a protracted cooling history, but that only a small number of thermochronometers supply permissible cooling ages in context. The thermal evolution of the Connemara region proposed here may be explained in context with current models of arc-continent collision, but also involves deep-seated driving processes.

  11. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells.

    Directory of Open Access Journals (Sweden)

    Congcong Chen

    Full Text Available Androgen receptor (AR signaling is crucial to the development and homeostasis of the prostate gland, and its dysregulation mediates common prostate pathologies. The mechanisms whereby AR regulates growth suppression and differentiation of luminal epithelial cells in the prostate gland and proliferation of malignant versions of these cells have been investigated in human and rodent adult prostate. However, the cellular stress response of human prostate epithelial cells is not well understood, though it is central to prostate health and pathology. Here, we report that androgen sensitizes HPr-1AR and RWPE-AR human prostate epithelial cells to cell stress agents and apoptotic cell death. Although 5α-dihydrotestosterone (DHT treatment alone did not induce cell death, co-treatment of HPr-1AR cells with DHT and an apoptosis inducer, such as staurosporine (STS, TNFt, or hydrogen peroxide, synergistically increased cell death in comparison to treatment with each apoptosis inducer by itself. We found that the synergy between DHT and apoptosis inducer led to activation of the intrinsic/mitochondrial apoptotic pathway, which is supported by robust cleavage activation of caspase-9 and caspase-3. Further, the dramatic depolarization of the mitochondrial membrane potential that we observed upon co-treatment with DHT and STS is consistent with increased mitochondrial outer membrane permeabilization (MOMP in the pro-apoptotic mechanism. Interestingly, the synergy between DHT and apoptosis inducer was abolished by AR antagonists and inhibitors of transcription and protein synthesis, suggesting that AR mediates pro-apoptotic synergy through transcriptional regulation of MOMP genes. Expression analysis revealed that pro-apoptotic genes (BCL2L11/BIM and AIFM2 were DHT-induced, whereas pro-survival genes (BCL2L1/BCL-XL and MCL1 were DHT-repressed. Hence, we propose that the net effect of these AR-mediated expression changes shifts the balance of BCL2-family proteins

  12. The burden of allergic rhinitis (AR in Canada: perspectives of physicians and patients

    Directory of Open Access Journals (Sweden)

    Keith Paul K


    Full Text Available Abstract Background Allergic rhinitis (AR is a common problem and we sought to examine the burden of disease and its management in Canada from the perspectives of patients and physicians. Methods Two parallel, Canadawide structured telephone interviews surveyed 1,001 AR patients and 160 physicians in July 2006. Results 44% of patients had experienced nasal symptoms unrelated to a cold and 20% had a physician diagnosis of AR. At screening 27% reported asthma, 15% chronic or recurrent sinusitis and 5% nasal polyps. With attacks nasal congestion and runny nose were the most bothersome symptoms. Other problems experienced were fatigue (46%, poor concentration (32%, and reduced productivity (23%. Most (77% had not seen a physician in the past year. Physicians estimated they prescribed intranasal cortico steroids (INCS to most AR patients (77% consistent with guidelines but only 19% of patients had used one in the last month. Only 48% of patients were very satisfied with their current INCS. 41% of AR patients reported discontinuing their INCS with the most common reason being a perceived lack of long-lasting symptom relief (44%. 52% of patients felt that their current INCS lost effectiveness over 24 h. The most common INCS side effects included dripping down the throat, bad taste, and dryness. Most AR patients reported lifestyle limitations despite treatment (66%. 61% of patients felt that their symptoms were only somewhat controlled or poorly/not controlled during their worst month in the past year. Conclusions AR symptoms are common and many patients experience inadequate control. Physicians report they commonly prescribe intranasal corticosteroids, but patient’s perceived loss of efficacy and side effects lead to their discontinuation. Persistent relief of allergic rhinitis symptoms remains a major unmet need. Better treatments and education are required.

  13. Discordant K-Ar and Young Exposure Dates for the Windjana Sandstone, Kimberley, Gale Crater, Mars (United States)

    Vasconcelos, P. M.; Farley, K. A.; Malespin, C. A.; Mahaffy, P.; Ming, D.; McLennan, S. M.; Hurowitz, J. A.; Rice, Melissa S.


    K-Ar and noble gas surface exposure age measurements were carried out on the Windjana sandstone, Kimberley region, Gale Crater, Mars, by using the Sample Analysis at Mars instrument on the Curiosity rover. The sandstone is unusually rich in sanidine, as determined by CheMin X-ray diffraction, contributing to the high K2O concentration of 3.09 +/- 0.20 wt % measured by Alpha-Particle X-ray Spectrometer analysis. A sandstone aliquot heated to approximately 915 C yielded a K-Ar age of 627 +/- 50 Ma. Reheating this aliquot yielded no additional Ar. A second aliquot heated in the same way yielded a much higher K-Ar age of 1710 +/- 110 Ma. These data suggest incomplete Ar extraction from a rock with a K-Ar age older than 1710 Ma. Incomplete extraction at approximately 900 C is not surprising for a rock with a large fraction of K carried by Ar-retentive K-feldspar. Likely, variability in the exact temperature achieved by the sample from run to run, uncertainties in sample mass estimation, and possible mineral fractionation during transport and storage prior to analysis may contribute to these discrepant data. Cosmic ray exposure ages from He-3 and Ne-21 in the two aliquots are minimum values given the possibility of incomplete extraction. However, the general similarity between the He-3 (57 +/- 49 and 18 +/- 32 Ma, mean 30 Ma) and Ne-21 (2 +/- 32 and 83 +/- 24 Ma, mean 54 Ma) exposure ages provides no evidence for underextraction. The implied erosion rate at the Kimberley location is similar to that reported at the nearby Yellowknife Bay outcrop.

  14. C3a Enhances the Formation of Intestinal Organoids through C3aR1

    Directory of Open Access Journals (Sweden)

    Naoya Matsumoto


    Full Text Available C3a is important in the regulation of the immune response as well as in the development of organ inflammation and injury. Furthermore, C3a contributes to liver regeneration but its role in intestinal stem cell function has not been studied. We hypothesized that C3a is important for intestinal repair and regeneration. Intestinal organoid formation, a measure of stem cell capacity, was significantly limited in C3-deficient and C3a receptor (C3aR 1-deficient mice while C3a promoted the growth of organoids from normal mice by supporting Wnt-signaling but not from C3aR1-deficient mice. Similarly, the presence of C3a in media enhanced the expression of the intestinal stem cell marker leucine-rich repeat G-protein-coupled receptor 5 (Lgr5 and of the cell proliferation marker Ki67 in organoids formed from C3-deficient but not from C3aR1-deficient mice. Using Lgr5.egfp mice we showed significant expression of C3 in Lgr5+ intestinal stem cells whereas C3aR1 was expressed on the surface of various intestinal cells. C3 and C3aR1 expression was induced in intestinal crypts in response to ischemia/reperfusion injury. Finally, C3aR1-deficient mice displayed ischemia/reperfusion injury comparable to control mice. These data suggest that C3a through interaction with C3aR1 enhances stem cell expansion and organoid formation and as such may have a role in intestinal regeneration.

  15. Cerebral A{sub 1} adenosine receptors (A{sub 1}AR) in liver cirrhosis

    Energy Technology Data Exchange (ETDEWEB)

    Boy, Christian [Research Centre Juelich, Brain Imaging Centre West, Institute of Medicine, Juelich (Germany); University Hospital Essen, Department of Nuclear Medicine, Essen (Germany); Meyer, Philipp T. [Research Centre Juelich, Brain Imaging Centre West, Institute of Medicine, Juelich (Germany); University Hospital Aachen, Department of Nuclear Medicine, Aachen (Germany); Kircheis, Gerald; Haussinger, Dieter [University of Duesseldorf, Clinic for Gastroenterology, Hepatology and Infectiology, Duesseldorf (Germany); Holschbach, Marcus H.; Coenen, Heinz H. [Research Centre Juelich, Institute of Nuclear Chemistry, Juelich (Germany); Herzog, Hans; Elmenhorst, David [Research Centre Juelich, Brain Imaging Centre West, Institute of Medicine, Juelich (Germany); Kaiser, Hans J. [University Hospital Aachen, Department of Nuclear Medicine, Aachen (Germany); Zilles, Karl [Research Centre Juelich, Brain Imaging Centre West, Institute of Medicine, Juelich (Germany); C. and O. Vogt Institute of Brain Research, Duesseldorf (Germany); Bauer, Andreas [Research Centre Juelich, Brain Imaging Centre West, Institute of Medicine, Juelich (Germany); University of Duesseldorf, Department of Neurology, Duesseldorf (Germany)


    The cerebral mechanisms underlying hepatic encephalopathy (HE) are poorly understood. Adenosine, a neuromodulator that pre- and postsynaptically modulates neuronal excitability and release of classical neurotransmitters via A{sub 1} adenosine receptors (A{sub 1}AR), is likely to be involved. The present study investigates changes of cerebral A{sub 1}AR binding in cirrhotic patients by means of positron emission tomography (PET) and [{sup 18}F]CPFPX, a novel selective A{sub 1}AR antagonist. PET was performed in cirrhotic patients (n = 10) and healthy volunteers (n = 10). Quantification of in vivo receptor density was done by Logan's non-invasive graphical analysis (pons as reference region). The outcome parameter was the apparent binding potential (aBP, proportional to B{sub max}/K{sub D}). Cortical and subcortical regions showed lower A{sub 1}AR binding in cirrhotic patients than in controls. The aBP changes reached statistical significance vs healthy controls (p < 0.05, U test with Bonferroni-Holm adjustment for multiple comparisons) in cingulate cortex (-50.0%), precentral gyrus (-40.9%), postcentral gyrus (-38.6%), insular cortex (-38.6%), thalamus (-32.9%), parietal cortex (-31.7%), frontal cortex (-28.6), lateral temporal cortex (-28.2%), orbitofrontal cortex (-27.9%), occipital cortex (-24.6), putamen (-22.7%) and mesial temporal lobe (-22.4%). Regional cerebral adenosinergic neuromodulation is heterogeneously altered in cirrhotic patients. The decrease of cerebral A{sub 1}AR binding may further aggravate neurotransmitter imbalance at the synaptic cleft in cirrhosis and hepatic encephalopathy. Different pathomechanisms may account for these alterations including decrease of A{sub 1}AR density or affinity, as well as blockade of the A{sub 1}AR by endogenous adenosine or exogenous xanthines. (orig.)

  16. Timescales and mechanisms of plume-lithosphere interactions: 40Ar/ 39Ar geochronology and geochemistry of alkaline igneous rocks from the Paraná-Etendeka large igneous province (United States)

    Gibson, S. A.; Thompson, R. N.; Day, J. A.


    We have determined high-precision 40Ar/ 39Ar ages for alkaline igneous rocks from the western margin of the Early-Cretaceous Paraná-Etendeka large igneous province (Paraguay). These show that small-fraction melt generation occurred beneath the region in two phases; at 145 Ma and 127.5 Ma, i.e. before and at the end of the 139-127.5 Ma Paraná-Etendeka flood-basalt eruptions. Previously published 40Ar/ 39Ar ages for alkaline igneous rocks on the proto-Atlantic coastal margins range from 134 to 128 Ma and indicate that small-fraction melt generation in the east of the province was either synchronous or slightly later than the main pulse of tholeiitic volcanism (between 134 and 132 Ma). Our new 40Ar/ 39Ar phlogopite ages confirm that: (i) the earliest melts associated with the initial impact of the Tristan plume were generated in the west of the Paraná-Etendeka large igneous province and (ii) igneous activity was long lived and immediately predates continental break-up. The Early-Cretaceous Paraguayan alkaline magmas are silica-undersaturated, enriched in incompatible-trace elements, have very-low initial ɛNd values and probably represent melts of phlogopite-bearing, carbonate-metasomatised peridotite in the subcontinental lithospheric mantle. Our simple one-dimensional, conductive-heating models suggest that the early-phase (145 Ma) alkaline magmas were emplaced on the margins of the Rio de La Plata craton at the time of sublithospheric impact of the proto-Tristan plume. The late phase (127.5 Ma) of Paraguayan alkaline magmatism is concentrated in an intra-cratonic rift zone and melt generation appears to have been triggered by lithospheric extension, perhaps facilitated by conductive heating and thermal weakening associated with the upwelling Tristan plume. The location and timing of both alkaline and tholeiitic melt generation in the Paraná-Etendeka province appear to have been significantly influenced by the non-uniform composition and thickness of the South

  17. Türkiye’de Ana Arı Üretiminin Değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Murat EMİR


    Full Text Available Bu çalışmanın temel amacı, Türkiye'de ana arı üretiminin mevcut durumunu tespit etmektir. Bu amaç çerçevesinde ülkemiz ana arı üretim kapasitesi ve üreticilerin durumuna ilişkin çözümler önerilecektir. Çalışmanın ana veri kaynağı, Türkiye ve diğer ülkelerde yapılan ilgili çalışmalardır. Bu çalışma, bu alanda yapılan çalışmaları gözden geçirerek genel çıkarımlara ulaşmak için sentezlemiştir. Ana arının performansı koloni performansını etkilemektedir. Ana arının kalitesi, koloni bal veriminde son derece önemlidir. Türkiye'nin koloni başına bal verimi 2014 yılında sadece 14 kg olurken, düşük verimin önemli nedenlerinden biri ana arı faktörüdür. Bakanlık tarafından yetkilendirilmiş 104 ana arı üreticisinin toplam yıllık kapasitesi 351 bin adettir. Bu üreticiler, ülkenin 28 ilinde faaliyet göstermektedirler. Türkiye genelinde yedi milyonu aşan koloni bulunmasından dolayı mevcut üreticilerin yıllık 351 bin ana arı üretim kapasitesi yeterli olmamaktadır. Türkiye’de ana arı üreticilerinin teknik ve ekonomik faaliyetlerini içeren işletme düzeyinde çalışma bulunmamaktadır. Ayrıca ana arı üretiminde üretici unsurları ve kalitesi konusunda yeterince çalışma mevcut değildir. Bunun yanında mevcut ana arı üretim işletmelerinin kapasitelerini artırabilme kabiliyeti ve sermaye gereksinimi üzerine çalışmalar bulunmamaktadır. Belirtilen ihtiyaca mevcut ana arı üreticilerinin kapasite artırım eğilimleri ve mevcut arıcılık işletmelerinin ana arı üreticiliği için ihtiyaç duyacağı ilave yatırım maliyetinin hesaplanması ile veriye dayalı yanıt aranmalıdır.

  18. Plastid and mitochondrion genomic sequences from Arctic Chlorella sp. ArM0029B. (United States)

    Jeong, Haeyoung; Lim, Jong-Min; Park, Jihye; Sim, Young Mi; Choi, Han-Gu; Lee, Jungho; Jeong, Won-Joong


    Chorella is the representative taxon of Chlorellales in Trebouxiophyceae, and its chloroplast (cp) genomic information has been thought to depend only on studies concerning Chlorella vulgaris and GenBank information of C. variablis. Mitochondrial (mt) genomic information regarding Chlorella is currently unavailable. To elucidate the evolution of organelle genomes and genetic information of Chlorella, we have sequenced and characterized the cp and mt genomes of Arctic Chlorella sp. ArM0029B. The 119,989-bp cp genome lacking inverted repeats and 65,049-bp mt genome were sequenced. The ArM0029B cp genome contains 114 conserved genes, including 32 tRNA genes, 3 rRNA genes, and 79 genes encoding proteins. Chlorella cp genomes are highly rearranged except for a Chlorella-specific six-gene cluster, and the ArM0029B plastid resembles that of Chlorella variabilis except for a 15-kb gene cluster inversion. In the mt genome, 62 conserved genes, including 27 tRNA genes, 3 rRNA genes, and 32 genes encoding proteins were determined. The mt genome of ArM0029B is similar to that of the non-photosynthetic species Prototheca and Heicosporidium. The ArM0029B mt genome contains a group I intron, with an ORF containing two LAGLIDADG motifs, in cox1. The intronic ORF is shared by C. vulgaris and Prototheca. The phylogeny of the plastid genome reveals that ArM0029B showed a close relationship of Chlorella to Parachlorella and Oocystis within Chlorellales. The distribution of the cox1 intron at 721 support membership in the order Chlorellales. Mitochondrial phylogenomic analyses, however, indicated that ArM0029B shows a greater affinity to MX-AZ01 and Coccomyxa than to the Helicosporidium-Prototheca clade, although the detailed phylogenetic relationships among the three taxa remain to be resolved. The plastid genome of ArM0029B is similar to that of C. variabilis. The mt sequence of ArM0029B is the first genome to be reported for Chlorella. Chloroplast genome phylogeny supports monophyly

  19. Registration Combining Wide and Narrow Baseline Feature Tracking Techniques for Markerless AR Systems

    Directory of Open Access Journals (Sweden)

    Bo Yang


    Full Text Available Augmented reality (AR is a field of computer research which deals with the combination of real world and computer generated data. Registration is one of the most difficult problems currently limiting the usability of AR systems. In this paper, we propose a novel natural feature tracking based registration method for AR applications. The proposed method has following advantages: (1 it is simple and efficient, as no man-made markers are needed for both indoor and outdoor AR applications; moreover, it can work with arbitrary geometric shapes including planar, near planar and non planar structures which really enhance the usability of AR systems. (2 Thanks to the reduced SIFT based augmented optical flow tracker, the virtual scene can still be augmented on the specified areas even under the circumstances of occlusion and large changes in viewpoint during the entire process. (3 It is easy to use, because the adaptive classification tree based matching strategy can give us fast and accurate initialization, even when the initial camera is different from the reference image to a large degree. Experimental evaluations validate the performance of the proposed method for online pose tracking and augmentation.

  20. Electrical studies of low energy Ar 9+ irradiated conducting polymer PANI-PVA (United States)

    Himanshu, A. K.; Bandyopadhayay, S. K.; Sen, Pintu; Nath Mondal, Nagendra; Talpatra, A.; Taki, G. S.; Sinha, T. P.


    Polyaniline (PANI) prepared using water soluble support polymer polyvinyl alcohol (PVA) was subjected to irradiation with 150 keV Argon (Ar 9+) ion at the fluence of 7.68×10 14 ion/cm 2 with beam current of 2 μA (electrical). There has been implantation of Ar atoms. The field dependence of dielectric response has been measured in the frequency range from 100 Hz to 1 MHz and in the temperature range from room temperature to the glass transition temperature. Dielectric constants have been found to be more for the Ar 9+-implanted polymer than for the pristine sample. The frequency dependence of the imaginary complex impedance ( Z″) is found to obey Arrhenius law with an activation energy of 0.29 eV for unirradiated and 0.53 eV for the Ar 9+-implanted polymer. Using the Cole-Cole model, an analysis of the real and imaginary parts of the impedance is performed, which reflects an increase in polydispersive nature after irradiation. Resistivity analysis shows three-dimensional (3D) Variable Range Hopping (VRH) at low temperature in contrast with two-dimensional (2D) VRH. There has been a decrease in the localization length as well as an increase in the energy gap due to the scission of bonds by the energy deposited by Ar 9+ ions.

  1. Electrical studies of low energy Ar{sup 9+} irradiated conducting polymer PANI-PVA

    Energy Technology Data Exchange (ETDEWEB)

    Himanshu, A.K., E-mail: [Variable Energy Cyclotron Centre, 1/AF, Bidhannagar, Kolkata 700 064 (India); Bandyopadhayay, S.K., E-mail: [Variable Energy Cyclotron Centre, 1/AF, Bidhannagar, Kolkata 700 064 (India); Sen, Pintu; Nath Mondal, Nagendra; Talpatra, A.; Taki, G.S. [Variable Energy Cyclotron Centre, 1/AF, Bidhannagar, Kolkata 700 064 (India); Sinha, T.P. [Department of Physics, Bose Institute, 93/1 A.P.C. Road, Kolkata 700 009 (India)


    Polyaniline (PANI) prepared using water soluble support polymer polyvinyl alcohol (PVA) was subjected to irradiation with 150 keV Argon (Ar{sup 9+}) ion at the fluence of 7.68x10{sup 14} ion/cm{sup 2} with beam current of 2 {mu}A (electrical). There has been implantation of Ar atoms. The field dependence of dielectric response has been measured in the frequency range from 100 Hz to 1 MHz and in the temperature range from room temperature to the glass transition temperature. Dielectric constants have been found to be more for the Ar{sup 9+}-implanted polymer than for the pristine sample. The frequency dependence of the imaginary complex impedance (Z'') is found to obey Arrhenius law with an activation energy of 0.29 eV for unirradiated and 0.53 eV for the Ar{sup 9+}-implanted polymer. Using the Cole-Cole model, an analysis of the real and imaginary parts of the impedance is performed, which reflects an increase in polydispersive nature after irradiation. Resistivity analysis shows three-dimensional (3D) Variable Range Hopping (VRH) at low temperature in contrast with two-dimensional (2D) VRH. There has been a decrease in the localization length as well as an increase in the energy gap due to the scission of bonds by the energy deposited by Ar {sup 9+} ions.

  2. Calibration of an ultra-low-background proportional counter for measuring 37Ar (United States)

    Seifert, A.; Aalseth, C. E.; Bonicalzi, R. M.; Bowyer, T. W.; Day, A. R.; Fuller, E. S.; Haas, D. A.; Hayes, J. C.; Hoppe, E. W.; Humble, P. H.; Keillor, M. E.; LaFerriere, B. D.; Mace, E. K.; McIntyre, J. I.; Merriman, J. H.; Miley, H. S.; Myers, A. W.; Orrell, J. L.; Overman, C. T.; Panisko, M. E.; Williams, R. M.


    An ultra-low-background proportional counter design has been developed at Pacific Northwest National Laboratory (PNNL) using clean materials, primarily electro-chemically-purified copper. This detector, along with an ultra-low-background counting system (ULBCS), was developed to complement a new shallow underground laboratory (30 meters water-equivalent) at PNNL. The ULBCS design includes passive neutron and gamma shielding, along with an active cosmic-veto system. This system provides a capability for making ultra-sensitive measurements to support applications like age-dating soil hydrocarbons with 14C/3H, age-dating of groundwater with 39Ar, and soil-gas assay for 37Ar to support On-Site Inspection (OSI). On-Site Inspection is a key component of the verification regime for the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Measurements of radionuclides created by an underground nuclear explosion are valuable signatures of a Treaty violation. For OSI, the 35-day half-life of 37Ar, produced from neutron interactions with calcium in soil, provides both high specific activity and sufficient time for inspection before decay limits sensitivity. This work describes the calibration techniques and analysis methods developed to enable quantitative measurements of 37Ar samples over a broad range of proportional counter operating pressures. These efforts, along with parallel work in progress on gas chemistry separation, are expected to provide a significant new capability for 37Ar soil gas background studies.

  3. Calibration of an Ultra-Low-Background Proportional Counter for Measuring 37Ar

    Energy Technology Data Exchange (ETDEWEB)

    Seifert, Allen; Aalseth, Craig E.; Bonicalzi, Ricco; Bowyer, Ted W.; Day, Anthony R.; Fuller, Erin S.; Haas, Derek A.; Hayes, James C.; Hoppe, Eric W.; Humble, Paul H.; Keillor, Martin E.; LaFerriere, Brian D.; Mace, Emily K.; McIntyre, Justin I.; Merriman, Jason H.; Miley, Harry S.; Myers, Allan W.; Orrell, John L.; Overman, Cory T.; Panisko, Mark E.; Williams, Richard M.


    Abstract. An ultra-low-background proportional counter (ULBPC) design has been developed at Pacific Northwest National Laboratory (PNNL) using clean materials, primarily electrochemically-purified copper. This detector, along with an ultra-low-background counting system (ULBCS), was developed to complement a new shallow underground laboratory (30 meters water-equivalent) constructed at PNNL. The ULBCS design includes passive neutron and gamma shielding, along with an active cosmic-veto system. This system provides a capability for making ultra-sensitive measurements to support applications like age-dating soil hydrocarbons with 14C/3H, age-dating of groundwater with 39Ar, and soil-gas assay for 37Ar to support On-Site Inspection (OSI). On-Site Inspection is a key component of the verification regime for the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Measurements of radionuclides created by an underground nuclear explosion are valuable signatures of a Treaty violation. For OSI, the 35-day half-life of 37Ar, produced from neutron interactions with calcium in soil, provides both high specific activity and sufficient time for inspection before decay limits sensitivity. This work describes the calibration techniques and analysis methods developed to enable quantitative measurements of 37Ar samples over a broad range of pressures. These efforts, along with parallel work in progress on gas chemistry separation, are expected to provide a significant new capability for 37Ar soil gas background studies.

  4. AR Feels "Softer" than VR: Haptic Perception of Stiffness in Augmented versus Virtual Reality. (United States)

    Gaffary, Yoren; Le Gouis, Benoit; Marchal, Maud; Argelaguet, Ferran; Arnaldi, Bruno; Lecuyer, Anatole


    Does it feel the same when you touch an object in Augmented Reality (AR) or in Virtual Reality (VR)? In this paper we study and compare the haptic perception of stiffness of a virtual object in two situations: (1) a purely virtual environment versus (2) a real and augmented environment. We have designed an experimental setup based on a Microsoft HoloLens and a haptic force-feedback device, enabling to press a virtual piston, and compare its stiffness successively in either Augmented Reality (the virtual piston is surrounded by several real objects all located inside a cardboard box) or in Virtual Reality (the same virtual piston is displayed in a fully virtual scene composed of the same other objects). We have conducted a psychophysical experiment with 12 participants. Our results show a surprising bias in perception between the two conditions. The virtual piston is on average perceived stiffer in the VR condition compared to the AR condition. For instance, when the piston had the same stiffness in AR and VR, participants would select the VR piston as the stiffer one in 60% of cases. This suggests a psychological effect as if objects in AR would feel "softer" than in pure VR. Taken together, our results open new perspectives on perception in AR versus VR, and pave the way to future studies aiming at characterizing potential perceptual biases.

  5. Role of glutathione and dependent enzymes in anthracycline-resistant HL60/AR cells. (United States)

    Lutzky, J; Astor, M B; Taub, R N; Baker, M A; Bhalla, K; Gervasoni, J E; Rosado, M; Stewart, V; Krishna, S; Hindenburg, A A


    We studied the cellular enzymatic defenses against anthracycline-induced free radical damage in the HL60 human myelogenous leukemia cell line and in its anthracycline-resistant subline, HL60/AR. Intracellular glutathione (GSH) levels and gamma-glutamyl transpeptidase activity were lower in HL60/AR than in HL60 cells. Glutathione-S-transferase (GST) and glutathione peroxidase activities were similar in both cell lines. The intracellular distribution of GSH/GST was visualized by digitized video fluorescence microscopy, utilizing the fluorescent probe monochlorobimane fluorescence microscopy, utilizing the fluorescent probe monochlorobimane (MBCl), which is specifically conjugated to GSH by GST. In HL60 cells stained with the MBCl probe, a bright diffuse cytoplasmic and nuclear fluorescence pattern was observed, whereas in HL60/AR cells, the fluorescence was mostly localized to the Golgi apparatus with a lesser component of diffuse cytoplasmic and nuclear fluorescence. Pretreatment of HL60/AR cells with buthionine sulfoximine (BSO) partially reversed resistance to daunorubicin. This effect of BSO on resistance was associated not only with the abolition of localized MBCl fluorescence to the Golgi apparatus but also with increased intracellular accumulation and retention of daunorubicin. The results of our studies demonstrate that inhibition of GSH synthesis in HL60/AR cells results in significant sensitization to daunorubicin and suggest that changes in the intracellular distribution of GSH/GST and/or increased drug retention may be involved in mediating this effect.

  6. Comparison of KrF and ArF excimer laser treatment of biopolymer surface

    Energy Technology Data Exchange (ETDEWEB)

    Michaljaničová, I. [Department of Solid State Engineering, University of Chemistry and Technology, 166 28 Prague (Czech Republic); Slepička, P., E-mail: [Department of Solid State Engineering, University of Chemistry and Technology, 166 28 Prague (Czech Republic); Heitz, J.; Barb, R.A. [Institute of Applied Physics, Johannes Kepler University Linz, A-4040 Linz (Austria); Sajdl, P. [Department of Power Engineering, University of Chemistry and Technology, 166 28 Prague (Czech Republic); Švorčík, V. [Department of Solid State Engineering, University of Chemistry and Technology, 166 28 Prague (Czech Republic)


    Highlights: • The influence of ArF and KrF laser on biopolymer surface was determined. • ArF laser acts predominantly on biopolymer surface. • PHB roughness is increased similarly for both applied wavelengths. • Roughness of nanostructures can be precisely controlled. • ArF laser introduces nitrogen on PHB surface. - Abstract: The goal of this work was the investigation of the impact of two different excimer lasers on two biocompatible and biodegradable polymers (poly-L-lactide and poly hydroxybutyrate). Both polymers find usage in medical and pharmaceutical fields. The polymers were modified by KrF and ArF excimer lasers. Subsequently the impact on surface morphology, surface chemistry changes, and thermal properties was studied by means of confocal and AFM microscopy, FTIR and XPS spectroscopy and DSC calorimetry. Under the same conditions of laser treatment it was observed that ArF laser causes more significant changes on surface chemistry, surface morphology and pattern formation on the polymers under investigation. The data obtained in this work can be used for a wide range of possible applications, in tissue engineering or in combination with metallization in electronics, e.g. for biosensors.

  7. ISWI contributes to ArsI insulator function in development of the sea urchin. (United States)

    Yajima, Mamiko; Fairbrother, William G; Wessel, Gary M


    Insulators are genomic elements that regulate transcriptional activity by forming chromatin boundaries. Various DNA insulators have been identified or are postulated in many organisms, and the paradigmatic CTCF-dependent insulators are perhaps the best understood and most widespread in function. The diversity of DNA insulators is, however, understudied, especially in the context of embryonic development, when many new gene territories undergo transitions in functionality. Here we report the functional analysis of the arylsulfatase insulator (ArsI) derived from the sea urchin, which has conserved insulator activity throughout the many metazoans tested, but for which the molecular mechanism of function is unknown. Using a rapid in vivo assay system and a high-throughput mega-shift assay, we identified a minimal region in ArsI that is responsible for its insulator function. We discovered a small set of proteins specifically bound to the minimal ArsI region, including ISWI, a known chromatin-remodeling protein. During embryogenesis, ISWI was found to interact with select ArsI sites throughout the genome, and when inactivated led to misregulation of select gene expression, loss of insulator activity and aberrant morphogenesis. These studies reveal a mechanistic basis for ArsI function in the gene regulatory network of early development.

  8. A Fault Diagnosis Approach for Gears Based on IMF AR Model and SVM

    Directory of Open Access Journals (Sweden)

    Yu Yang


    Full Text Available An accurate autoregressive (AR model can reflect the characteristics of a dynamic system based on which the fault feature of gear vibration signal can be extracted without constructing mathematical model and studying the fault mechanism of gear vibration system, which are experienced by the time-frequency analysis methods. However, AR model can only be applied to stationary signals, while the gear fault vibration signals usually present nonstationary characteristics. Therefore, empirical mode decomposition (EMD, which can decompose the vibration signal into a finite number of intrinsic mode functions (IMFs, is introduced into feature extraction of gear vibration signals as a preprocessor before AR models are generated. On the other hand, by targeting the difficulties of obtaining sufficient fault samples in practice, support vector machine (SVM is introduced into gear fault pattern recognition. In the proposed method in this paper, firstly, vibration signals are decomposed into a finite number of intrinsic mode functions, then the AR model of each IMF component is established; finally, the corresponding autoregressive parameters and the variance of remnant are regarded as the fault characteristic vectors and used as input parameters of SVM classifier to classify the working condition of gears. The experimental analysis results show that the proposed approach, in which IMF AR model and SVM are combined, can identify working condition of gears with a success rate of 100% even in the case of smaller number of samples.

  9. Improved androgen specificity of AR-EcoScreen by CRISPR based glucocorticoid receptor knockout. (United States)

    Zwart, Nick; Andringa, Dave; de Leeuw, Willem-Jan; Kojima, Hiroyuki; Iida, Mitsuru; Houtman, Corine J; de Boer, Jacob; Kool, Jeroen; Lamoree, Marja H; Hamers, Timo


    The AR-EcoScreen is a widely used reporter assay for the detection of androgens and anti-androgens. Endogenous expression of glucocorticoid receptors and their affinity for the androgen responsive element that drives reporter expression, however, makes the reporter cells sensitive to interference by glucocorticoids and less specific for (anti-)androgens. To create a glucocorticoid insensitive derivative of the AR-EcoScreen, CRISPR/Cas9 genome editing was used to develop glucocorticoid receptor knockout mutants by targeting various sites in the glucocorticoid gene. Two mutant cell lines were further characterized and validated against the unmodified AR-EcoScreen with a set of 19 environmentally relevant chemicals and a series of environmental passive sampler extracts with (anti-)androgenic activity. Sequencing of the targeted sites revealed premature stop codons following frame-shift mutations, leading to an absence of functional glucocorticoid receptor expression. The introduced mutations rendered cell lines insensitive to glucocorticoid activation and caused no significant difference in the responsiveness towards (anti-)androgens, compared to the unmodified AR-EcoScreen cells, allowing the selective, GR-independent, determination of (anti-)androgenicity in environmental passive sampler extracts. The increase in selectivity for (anti-)androgens improves reliability of the AR-EcoScreen and will provide higher accuracy in determining (anti-)androgenic potential when applied in toxicity screening and environmental monitoring of both single compounds and mixtures. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Learning Science Using AR Book: A Preliminary Study on Visual Needs of Deaf Learners (United States)

    Megat Mohd. Zainuddin, Norziha; Badioze Zaman, Halimah; Ahmad, Azlina

    Augmented Reality (AR) is a technology that is projected to have more significant role in teaching and learning, particularly in visualising abstract concepts in the learning process. AR is a technology is based on visually oriented technique. Thus, it is suitable for deaf learners since they are generally classified as visual learners. Realising the importance of visual learning style for deaf learners in learning Science, this paper reports on a preliminary study of on an ongoing research on problems faced by deaf learners in learning the topic on Microorganisms. Being visual learners, they have problems with current text books that are more text-based that graphic based. In this preliminary study, a qualitative approach using the ethnographic observational technique was used so that interaction with three deaf learners who are participants throughout this study (they are also involved actively in the design and development of the AR Book). An interview with their teacher and doctor were also conducted to identify their learning and medical problems respectively. Preliminary findings have confirmed the need to design and develop a special Augmented Reality Book called AR-Science for Deaf Learners (AR-SiD).

  11. Constraining the age of the Matuyama-Brunhes reversal using intercalibrated 40Ar/39Ar and astronomical ages of the Bishop Tuff and Australasian Tektite

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Palike, Heiko

    Recent high-resolution δ18O records from North Atlantic (I)ODP cores, with reliable paleomagnetic signals, have placed the mean age of the Matuyama-Brunhes (MB) geomagnetic polarity reversal ca. 8 ka younger than previous estimates when correlated to ice-volume age models (Channell et al., 2010......). However, this age offset is not synchronous with a new astronomically intercalibrated 40Ar/39Ar age for the normal-polarity Quaternary Bishop Tuff, stratigraphically above the MB boundary by approximately 15 ka. In order to best constrain the age of the boundary, an astronomically calibrated radio......-isotopic age is needed on a datable unit from the reversed-polarity side of the MB boundary. The Australasian tektite is a suitable unit from the Matuyama chron for dating the MB boundary because the positions of microtektite layers relative to the MB boundary have been documented in (I)ODP and other drill...

  12. Les Amours d’Arès et Aphrodite, la critique homérique et la pantomime dans l’Ars amatoria


    Jean-Christophe Jolivet


    Le traitement de l'épisode des Amours d'Arès et Aphrodite dans le chant 2 de l'Ars amatoria laisse supposer que les commentaires homériques ont exercé une influence sur la version ovidienne, non seulement quant à l'interprétation didactique du mythe, mais également du fait que le chant de Démodocos était considéré par certains interprètes comme l'illustration archaïque d'un registre comique et érotique. Par ailleurs, un certain nombre d'indices laissent supposer une référence à la pantomime d...

  13. Bioremediación de arsénico mediante la formación de minerales de sulfuro de arsénico


    Regodón Trujillo, Diego Álvaro


    La bioremediación de aguas contaminadas con arsénico mediante la formación de minerals de sulfuro de arsénico ha sido probada con éxito usando la reducción microbiana simultanea de arsenato y sulfato, pero solo bajo estrictas condiciones de pH < 7 y un ratio estequiométrico de S/As. El principal objetivo de esta investigación es evaluar la eficacia de este método usando ratios S/As alejados del valor estequiométrico y con un pH < 7. Departamento de Ingeniería Química y Tecnología del Medio...

  14. Preservation of ancient impact ages on the R chondrite parent body: 40Ar/39Ar age of hornblende-bearing R chondrite LAP 04840 (United States)

    Righter, K.; Cosca, M. A.; Morgan, L. E.


    The hornblende- and biotite-bearing R chondrite LAP 04840 is a rare kind of meteorite possibly containing outer solar system water stored during metamorphism or postshock annealing deep within an asteroid. Because little is known regarding its age and origin, we determined 40Ar/39Ar ages on hornblende-rich separates of the meteorite, and obtained plateau ages of 4340(±40) to 4380(±30) Ma. These well-defined plateau ages, coupled with evidence for postshock annealing, indicate this meteorite records an ancient shock event and subsequent annealing. The age of 4340-4380 Ma (or 4.34-4.38 Ga) for this and other previously dated R chondrites is much older than most impact events recorded by ordinary chondrites and points to an ancient event or events that predated the late heavy bombardment that is recorded in so many meteorites and lunar samples.

  15. NW termination of the West Cycladic Detachment System on the Lavrion Peninsula, Greece: results from mica 40Ar/39Ar geochronology (United States)

    Schneider, David; Dubosq, Renelle; Spalding, Jennifer; Grasemann, Bernhard; Soukis, Kostis


    The West Cycladic Detachment System (WCDS) has been mapped from the western Cycladic islands to the Lavrion peninsula, where several top-to-SSW low-angle normal faults at different structural levels are observed. The dominant detachment juxtaposes lower plate schistose to mylonitic rocks of the Kamariza Unit against the upper plate Lavrion Unit. The Kamariza Unit exhibits a NNE-SSW stretching lineation whereas the main foliation in the Lavrion Unit is a compressional crenulation cleavage with ENE-WSW to NE-SW stretching and intersection lineations. Kinematic indicators reveal top-to-SSW sense of shear, and along the detachment both units are overprinted by cataclastic deformation and high-temperature metallic ore mineralization. White mica-bearing schists and marbles were collected for microstructural and 40Ar/39Ar geochronology. Quartz crystals in all samples show subgrain rotation and bulging of grains, indicated by lobate grain boundaries. These same rocks contain interconnected elongated mica crystals, which are kinked or internally deformed by C'-type shear zones. White mica is rarely prismatic, and chemical mapping highlights the chemical zonation of the muscovite. Calcite, when present, exhibits curved and tapered twins. Glaucophane and chlorite pseudomorphs of glacophane are preserved in the Lavrion Unit. New single-crystal 40Ar/39Ar geochronology on muscovite from the upper plate Lavrion Unit of the peninsula yields ages between 35-28 Ma, and together with published zircon (U-Th)/He dates of 16-12 Ma and preservation of glaucophane suggests these rocks did not witness the dominant Miocene greenschist facies deformation that characterizes the WCDS. One muscovite sample along the west coast at Thimari yielded an 40Ar/39Ar age of c. 175 Ma (duplicate analyses) and maybe part of the Sub-Pelagonian Berzekos Unit. Comparatively, the Kamariza Unit yields Early to Middle Miocene 40Ar/39Ar ages, and coupled with Late Miocene zircon (U-Th)/He ages and top

  16. Eocene-Miocene igneous activity in Provence (SE France): 40Ar/39Ar data, geochemical-petrological constraints and geodynamic implications (United States)

    Lustrino, Michele; Fedele, Lorenzo; Agostini, Samuele; Di Vincenzo, Gianfranco; Morra, Vincenzo


    Provence (SE France) was affected by two main phases of sporadic igneous activity during the Cenozoic. New 40Ar/39Ar laser step-heating data constrain the beginning of the oldest phase to late Eocene (40.82 ± 0.73 Ma), with activity present until early Miocene ( 20 Ma). The products are mainly andesites, microdiorites, dacites and basaltic andesites mostly emplaced in the Agay-Estérel area. Major- and trace-element constraints, together with Srsbnd Ndsbnd Pb isotopic ratios suggest derivation from a sub-continental lithosphere mantle source variably modified by subduction-related metasomatic processes. The compositions of these rocks overlap those of nearly coeval (emplaced 38-15 Ma) late Eocene-middle Miocene magmatism of Sardinia. The genesis of dacitic rocks cannot be accounted for by simple fractional crystallization alone, and may require interaction of evolved melts with lower crustal lithologies. The youngest phase of igneous activity comprises basaltic volcanic rocks with mildly sodic alkaline affinity emplaced in the Toulon area 10 Myr after the end of the previous subduction-related phase. These rocks show geochemical and isotopic characteristics akin to magmas emplaced in intraplate tectonic settings, indicating a sub-lithospheric HiMu + EM-II mantle source for the magmas, melting approximately in the spinel/garnet-lherzolite transition zone. New 40Ar/39Ar laser step-heating ages place the beginning of the volcanic activity in the late Miocene-Pliocene (5.57 ± 0.09 Ma). The emplacement of ;anorogenic; igneous rocks a few Myr after rocks of orogenic character is a common feature in the Cenozoic districts of the Central-Western Mediterranean area. The origin of such ;anorogenic; rocks can be explained with the activation of different mantle sources not directly modified by subduction-related metasomatic processes, possibly located in the sub-lithospheric mantle, and thus unrelated to the shallower lithospheric mantle source of the ;orogenic; magmatism.

  17. Age and thermal history of the Geysers plutonic complex (felsite unit), Geysers geothermal field, California: A 40Ar/39Ar and U-Pb study (United States)

    Dalrymple, G.B.; Grove, M.; Lovera, O.M.; Harrison, T.M.; Hulen, J.B.; Lanphere, M.A.


    Sixty-nine ion microprobe spot analyses of zircons from four granite samples from the plutonic complex that underlies the Geysers geothermal field yield 207Pb/206Pb vs. 238U/206Pb concordia ages ranging from 1.13 ?? 0.04 Ma to 1.25 ?? 0.04 (1??) Ma. The weighted mean of the U/Pb model ages is 1.18 ?? 0.03 Ma. The U-Pb ages coincide closely with 40Ar/39Ar age spectrum plateau and 'terminal' ages from coexisting K-feldspars and with the eruption ages of overlying volcanic rocks. The data indicate that the granite crystallized at 1.18 Ma and had cooled below 350??C by ~0.9-1.0 Ma. Interpretation of the feldspar 40Ar/39Ar age data using multi-diffusion domain theory indicates that post-emplacement rapid cooling was succeeded either by slower cooling from 350??to 300??C between 1.0 and 0.4 Ma or transitory reheating to 300-350??C at about 0.4-0.6 Ma. Subsequent rapid cooling to below 260??C between 0.4 and 0.2 Ma is in agreement with previous proposals that vapor-dominated conditions were initiated within the hydrothermal system at this time. Heat flow calculations constrained with K-feldspar thermal histories and the present elevated regional heat flow anomaly demonstrate that appreciable heat input from sources external to the known Geysers plutonic complex is required to maintain the geothermal system. This requirement is satisfied by either a large, underlying, convecting magma chamber (now solidified) emplaced at 1.2 Ma or episodic intrusion of smaller bodies from 1.2 to 0.6 Ma.

  18. A Rhaetian 40Ar/39Ar age for the Rochechouart impact structure (France) and implications for the latest Triassic sedimentary record (United States)

    Schmieder, Martin; Buchner, Elmar; Schwarz, Winfried H.; Trieloff, Mario; Lambert, Philippe


    40Ar/39Ar dating of potassium feldspar (primary spherulitic-blocky and secondary idiomorphic K-feldspar) separated from impact-metamorphosed gneiss found near Videix in the western central part of the Rochechouart impact structure (NW Massif Central, France) yielded a Rhaetian combined age of 201+/-2Ma (2σ), indistinguishable within uncertainty from the age of the Triassic/Jurassic boundary. Ballen quartz intergrown with the primary K-feldspar indicates post-shock temperatures exceeding approximately 1000°C that affected the precursor gneiss. Geochemically, both feldspar types represent essentially pure potassium end-members. Apart from the approximately 15km diameter impact deposit area, the youngest crystallization age known for basement rocks in this part of the Massif Central is approximately 300Ma. No endogenic magmatic-thermal events are known to have occurred later in this region. The K-feldspar recrystallized from local feldspar melts and superimposed post-shock hydrothermal crystallization, probably within some thousands of years after the impact. It is, therefore, suggested that the 40Ar/39Ar age for the Videix gneiss (as a potassic ``impact metasomatite'') dates the Rochechouart impact, in consistence with evidence for K-metasomatism in the Rochechouart impactites. The new age value is distinctly younger than the previously obtained Karnian-Norian age for Rochechouart and, thus, contradicts the Late Triassic multiple impact theory postulated some years ago. In agreement with the paleogeographic conditions in the western Tethys domain around the Triassic/Jurassic boundary, the near-coastal to shallow marine Rochechouart impact is compatible with the formation of seismites and tsunami deposits in the latest Triassic of the British Isles and possible related deposits in other parts of Europe.

  19. Dating slate belts using 40Ar/39Ar geochronology and zircon ages from crosscutting plutons: A case study from east-central Maine, USA (United States)

    Ghanem, Hind; Kunk, Michael J.; Ludman, Allan; Bish, David L.; Wintsch, Robert P.


    We report the ages of cleavage development in a normally intractable lower greenschist facies slate belt, the Central Maine-Aroostook-Matapedia belt in east-central Maine. We have attacked this problem by identifying the minimum ages of muscovite in a regional Acadian cleavage (S1) and in a local ductile fault zone cleavage (S2) using 40Ar/39Ar geochronology and the ages of crosscutting plutons. Our success stems from the regional low-grade metamorphism of the rocks in which each crystallization event preserves a40Ar/39Ar crystallization age and not a cooling age. Evidence for recrystallization via a pressure solution mechanism comes from truncations of detrital, authigenic, and in some rocks S1 muscovite and chlorite grains by new cleavage-forming muscovite and chlorite grains. Low-blank furnace age spectra from meta-arkosic and slaty rocks climb from moderate temperature Devonian age-steps dominated by cleavage-forming muscovite to Ordovician age-steps dominated by a detrital muscovite component. S1- and S2-cleaved rocks were hornfelsed by granitoids of ∼407 and 377 Ma, respectively. The combination of these minimum ages with the maximum metamorphic crystallization ages establishes narrow constraints on the timing of these two cleavage-forming events, ∼410 Ma (S1) and ∼380 Ma (S2). These two events coincide in time with a change in the plate convergence kinematics from the arrival of the Avalon terrane (Acadian orogeny), to a right-lateral transpression arrival of the Meguma terrane in the Neoacadian orogeny.

  20. Iekšējas saskaņotības izjūtas saistība ar apmierinātību ar darbu


    Arāja, Agnese


    Bakalaura darba mērķis bija noskaidrot vai pastāv iekšējās saskaņotības izjūtas saistība ar apmierinātību ar darbu. Pētījuma izlase sastāv no 60 respondentiem, 30 vīriešiem un 30 sievietēm, vienā organizācijā strādājošiem tirdzniecības darbiniekiem, vecumā no 18 līdz 40 gadiem. Lai noteiktu attiecības starp iekšējās saskaņotības izjūtu un apmierinātību ar darbu tika attiecīgi izmantotas Antonovska iekšējās saskaņotības izjūtas skala (Sense of Coherence Scale), ko izveidojis Antonovskais 1987....

  1. Fenofibrate down-regulates the expressions of androgen receptor (AR) and AR target genes and induces oxidative stress in the prostate cancer cell line LNCaP

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Hu; Zhu, Chen; Qin, Chao [State Key Laboratory of Reproductive Medicine, Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing (China); Tao, Tao [Department of Neurosurgery, First Affiliated Hospital of Nanjing Medical University, Nanjing (China); Li, Jie; Cheng, Gong; Li, Pu; Cao, Qiang; Meng, Xiaoxin; Ju, Xiaobing; Shao, Pengfei; Hua, Lixin [State Key Laboratory of Reproductive Medicine, Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing (China); Gu, Min, E-mail: [State Key Laboratory of Reproductive Medicine, Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing (China); Yin, Changjun, E-mail: [State Key Laboratory of Reproductive Medicine, Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing (China)


    Highlights: ► Fenofibrate induces cell cycle arrest in G1 phase and apoptosis in LNCaP cells. ► Fenofibrate reduces the expressions of androgen receptor in LNCaP cells. ► Fenofibrate induces oxidative stress in the prostate cancer cell line LNCaP. -- Abstract: Fenofibrate, a peroxisome proliferator-androgen receptor-alpha agonist, is widely used in treating different forms of hyperlipidemia and hypercholesterolemia. Recent reports have indicated that fenofibrate exerts anti-proliferative and pro-apoptotic properties. This study aims to investigate the effects of fenofibrate on the prostate cancer (PCa) cell line LNCaP. The effects of fenofibrate on LNCaP cells were evaluated by flow cytometry, reverse transcription-polymerase chain reaction, enzyme-linked immunosorbent assays, Western blot analysis, and dual-luciferase reporter assay. Fenofibrate induces cell cycle arrest in G1 phase and apoptosis in LNCaP cells, reduces the expressions of androgen receptor (AR) and AR target genes (prostate-specific antigen and TMPRSS2), and inhibits Akt phosphorylation. Fenofibrate can induce the accumulation of intracellular reactive oxygen species and malondialdehyde, and decrease the activities of total anti-oxidant and superoxide dismutase in LNCaP cells. Fenofibrate exerts an anti-proliferative property by inhibiting the expression of AR and induces apoptosis by causing oxidative stress. Therefore, our data suggest fenofibrate may have beneficial effects in fenofibrate users by preventing prostate cancer growth through inhibition of androgen activation and expression.

  2. Growth of mica porphyroblasts under low-grade metamorphism - A Taiwanese case using in-situ40Ar/39Ar laser microprobe dating (United States)

    Chen, Chih-Tung; Chan, Yu-Chang; Lo, Ching-Hua; Lu, Chia-Yu


    Mica porphyroblasts, a common metamorphic microstructure, are analyzed in the slate belt of northern Taiwan where large fish-like growths are found within a meta-pyroclastics. With constraints on the time-temperature history from deposition through peak metamorphic state to exhumation, in-situ40Ar/39Ar laser microprobe dating was carried out on muscovite and corrensite fibers of mm-scale mica porphyroblasts grown on a pressure-solution seam. Because the peak metamorphic temperature and the porphyroblast formation condition (∼250 °C) remained far below the closure temperature of the K-Ar radioisotope system in muscovite, and the absence of muscovite in the mafic protolith, the dating results likely document the growth of the mica porphyroblast fabrics. The syn-kinematic nature of the analyzed porphyroblasts is confirmed by the ∼6 to ∼2.5 Ma growth ages, suggesting that the host rock was continuously deformed during the earlier two-thirds of the Taiwan Orogeny. The pattern of fiber growth, in contrast to outward-decreasing ages normally observed in peripheral recrystallization, appears random and resembles void fills in boudin openings. We postulate that syntaxial crack-seal following tensile micro-boudinage, along with slips on sub-grain boundaries, as a viable mechanism for the development of mica porphyroblasts and fish especially in lower-grade metamorphic rocks.

  3. Ar-40 to Ar-39 ages of the large impact structures Kara and Manicouagan and their relevance to the Cretaceous-Tertiary and the Triassic-Jurassic boundary (United States)

    Trieloff, M.; Jessberger, E. K.


    Since the discovery of the Ir enrichment in Cretaceous-Tertiary boundary clays in 1980, the effects of a 10-km asteroid impacting on the Earth 65 Ma ago have been discussed as the possible reason for the mass extinction--including the extinction of the dinosaurs--at the end of the Cretaceous. But up to now no crater of this age that is large enough (ca. 200 km in diameter) has been found. One candidate is the Kara Crater in northern Siberia. Kolesnikov et al. determined a K-Ar isochron of 65.6 +/- 0.5 Ma, indistinguishable from the age of the K-T boundary and interpreted this as confirmation of earlier proposals that the Kara bolide would have been at least one of the K-T impactors. Koeberl et al. determined Ar-40 to Ar-39 ages ranging from 70 to 82 Ma and suggested an association to the Campanian-Maastrichtian boundary, another important extinction horizon 73 Ma ago. We dated four impact melts, KA2-306, KA2-305, SA1-302, and AN9-182. Results from the investigation are discussed.

  4. Analysis of the tourism potential in the Campo Grande and Guaratiba Administrative Regions (ARs, west Rio de Janeiro's Municipality (Brazil

    Directory of Open Access Journals (Sweden)

    Vivian Castilho da Costa


    Full Text Available This work summarizes the study conducted in two Administrative Regions (ARs of west Rio de Janeiro's Municipality, namely: Campo Grande AR and Garatiba AR. The main objectives were: assess the development and potential of tourism activities in these two ARs through the use of geo-processing techniques, and propose general guidelines for application. The analysis of key findings was carried out separately for each AR, as they represent areas facing different realities despite their geographic proximity. This process revealed the short-term need of better municipal and state planning in relation of the distribution an characterization of spaces reserved for urban expansion. The assessment of tourism potential also showed significant differences in occupation processes between these two ARs, as well as in the nature of the activities required to make an optimum use of this potential.


    Directory of Open Access Journals (Sweden)

    Futuhal Arifin


    Full Text Available Abstract Nowadays, there are many robotic applications being developed to do tasks autonomously without any interactions or commands from human. Therefore, developing a system which enables a robot to do surveillance such as detection and tracking of a moving object will lead us to more advanced tasks carried out by robots in the future. AR.Drone is a flying robot platform that is able to take role as UAV (Unmanned Aerial Vehicle. Usage of computer vision algorithm such as Hough Transform makes it possible for such system to be implemented on AR.Drone. In this research, the developed algorithm is able to detect and track an object with certain shape and color. Then the algorithm is successfully implemented on AR.Drone quadcopter for detection and tracking.

  6. Multi-viewpoint Smartphone AR-based Learning System for Solar Movement Observations

    Directory of Open Access Journals (Sweden)

    Ke Tian


    Full Text Available Understanding solar movement (e.g., solar diurnal motion is difficult for those are beginning to learn about astronomy. Previous research has revealed that observation-based learning can help make astronomical phenomena clearer to understand for such learners. In this research, Smartphone Augmented Reality (AR technology and 3D content were used to develop a multi-viewpoint Smartphone AR-based learning system (M-VSARLS for solar movement observations that can be used in the real-world environment. The goal of this research is to assess the usefulness of the system, usability of the AR function and 3D content, and the overall effect of the system on the learner’s motivation through task-based experiments with follow-up questionnaires. The results show that the M-VSARL system is effective in improving the observational skills and learning ability of learners, and in enhancing their motivation to learn about solar movement.

  7. Polymorphisms in the AR and PSA genes as markers of susceptibility and aggressiveness in prostate cancer

    DEFF Research Database (Denmark)

    Kuasne, Hellen; Rodrigues, Iara Sant'Ana; Fuganti, Paulo Emílio


    The study of genes involved in androgen pathway can contribute to a better knowledge of prostate cancer. Our aim was to examine if polymorphisms in prostate-specific antigen (PSA) and androgen receptor (AR) genes were involved in prostate cancer risk and aggressiveness. Genotypes were determined...... by PCR-RFLP (PSA) or using a 377 ABI DNA Sequencer (AR). PSA(G/G) genotype (OR = 1.78, 95% CI = 1.06–2.99) and AR short CAG repeats (OR = 1.89, 95% CI = 1.21–2.96) increased risk for prostate cancer and were related with tumor aggressiveness. About 38.3% of tumors showed microsatellite instability...

  8. Behavioral pharmacology of AR-A000002, a novel, selective 5-hydroxytryptamine(1B) antagonist. (United States)

    Hudzik, T J; Yanek, M; Porrey, T; Evenden, J; Paronis, C; Mastrangelo, M; Ryan, C; Ross, S; Stenfors, C


    The present review summarizes the behavioral pharmacology conducted to profile the anxiolytic and antidepressant potential of the selective 5-hydroxytryptamine (HT)(1B) antagonist (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide (AR-A000002). AR-A000002 functions as a 5-HT(1B) antagonist in vivo, which was shown by the antagonism of the discriminative stimulus effects in the guinea pig of the 5-HT(1B) agonist 3-(N-methylpyrrolidin-2R-ylmethyl)-5-(3-nitropyrid-2-ylamino)-lH-indole (CP135,807). Anxiolytic activity of AR-A000002 was demonstrated in the separation-induced vocalization paradigm in guinea pig pups, and in a suppressed responding procedure in pigeons and guinea pigs, but only a weak trend was noted in a suppressed responding procedure in squirrel monkeys. Antidepressant efficacy was shown in a number of paradigms. In pigeons and guinea pigs responding under a differential reinforcement of low rates schedule of reinforcement (DRL), AR-A000002 increased the number of reinforcers earned without altering the number of responses made. In guinea pigs trained under a response duration differentiation paradigm, AR-A000002 increased mean lever-press duration. Finally, AR-A000002 was shown to block escape failures in guinea pigs submitted to a learned helplessness paradigm. Taken together, these data suggest utility for 5-HT(1B) antagonists in the treatment of both anxiety and affective disorders.

  9. Succinate/NLRP3 inflammasome induces synovial fibroblast activation: therapeutical effects of clematichinenoside AR on arthritis

    Directory of Open Access Journals (Sweden)

    Yi Li


    Full Text Available Clematichinenoside AR (C-AR is a triterpene saponin isolated from the root of Clematis manshurica Rupr., which is a herbal medicine used in traditional Chinese medicine for the treatment of arthritis. C-AR exerts anti-inflammatory and immunosuppressive properties, but little is known about its action in the suppression of fibroblast activation. Low oxygen tension and TGF-β1 induction in the synovium contribute to fibrosis in arthrits. This study was designed to investigate the effect of clematichinenoside AR (C-AR on synovial fibrosis from the aspects of hypoxic TGF-β1 and HIF-1α induction. In the synovium of rheumatoid arthritis rats, hypoxic TGF-β1 induction increased succinate accumulation due to the reversal of SDH activation and induced NLRP3 inflammasome activation in a manner dependent on HIF-1α induction. In response to NLRP3 inflammsome activation, the released IL-1β further increased TGF-β1 induction, suggesting the forward cycle between inflammation and fibrosis in myofibroblast activation. In the synovium of rheumatoid arthritis rats, C-AR inhibited hypoxic TGF-β1 induction and suppressed succinate-associated NLRP3 inflammasome activation by inhibiting SDH activity, and thereby prevented myofibroblast activation by blocking the cross-talk between inflammation and fibrosis. Taken together, these results showed that succinate worked as a metabolic signaling, linking inflammation with fibrosis through NLRP3 inflammasome activation. These findings suggested that synovial succinate accumulation and HIF-1α induction might be therapeutical targets for the prevention of fibrosis in arthritis.

  10. Expression of ARs in triple negative breast cancer tumors: a potential prognostic factor?

    Directory of Open Access Journals (Sweden)

    Giannos A


    Full Text Available Aris Giannos,1 Martin Filipits,2 Flora Zagouri,2,3 Anita Brandstetter,2 Alexandra Tsigginou,1 Maria Sotiropoulou,4 Irene Papaspyrou,4 Theodoros N Sergentanis,5 Theodora Psaltopoulou,5 Alexandros Rodolakis,1 Aris Antsaklis,1 Meletios-Athanasios Dimopoulos,2 Constantine Dimitrakakis1 1Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece; 2Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; 3Department of Clinical Therapeutics, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece; 4Department of Pathology, Alexandra General Hospital, Athens, Greece; 5Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece Background/aim: In light of the controversial published literature, this study aims to examine the potential prognostic role of AR immunohistochemical expression in triple negative breast cancer (TNBC.Patients and methods: Ninety patients with TNBC were included in this study; the associations between AR expression (Allred score, clinicopathological variables (stage, grade, histological subtype, tumor size, nodal status, age at diagnosis, Ki67 expression, and p53 expression, and overall survival were evaluated.Results: AR expression was not associated with stage, grade, histological subtype, tumor size, nodal status, age at diagnosis, Ki67 expression, and p53 expression. AR immunopositivity was not associated with overall survival either at the univariate or at the multivariate Cox regression analysis (multivariate hazard ratio =0.66, 95% confidence interval: 0.26–1.70, P=0.393.Conclusion: AR expression does not seem to play a prognostic role in TNBC. Keywords: biomarkers, prognosis, AR, triple negative breast cancer

  11. A single cell level measurement of StAR expression and activity in adrenal cells. (United States)

    Lee, Jinwoo; Yamazaki, Takeshi; Dong, Hui; Jefcoate, Colin


    The Steroidogenic acute regulatory protein (StAR) directs mitochondrial cholesterol uptake through a C-terminal cholesterol binding domain (CBD) and a 62 amino acid N-terminal regulatory domain (NTD) that contains an import sequence and conserved sites for inner membrane metalloproteases. Deletion of the NTD prevents mitochondrial import while maintaining steroidogenesis but with compromised cholesterol homeostasis. The rapid StAR-mediated cholesterol transfer in adrenal cells depends on concerted mRNA translation, p37 StAR phosphorylation and controlled NTD cleavage. The NTD controls this process with two cAMP-inducible modulators of, respectively, transcription and translation SIK1 and TIS11b/Znf36l1. High-resolution fluorescence in situ hybridization (HR-FISH) of StAR RNA resolves slow RNA splicing at the gene loci in cAMP-induced Y-1 cells and transfer of individual 3.5 kB mRNA molecules to mitochondria. StAR transcription depends on the CREB coactivator CRTC2 and PKA inhibition of the highly inducible suppressor kinase SIK1 and a basal counterpart SIK2. PKA-inducible TIS11b/Znf36l1 binds specifically to highly conserved elements in exon 7 thereby suppressing formation of mRNA and subsequent translation. Co-expression of SIK1, Znf36l1 with 3.5 kB StAR mRNA may limit responses to pulsatile signaling by ACTH while regulating the transition to more prolonged stress. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. Vibrational dynamics of aniline(Ar)1 and aniline(CH4)1 clusters (United States)

    Nimlos, M. R.; Young, M. A.; Bernstein, E. R.; Kelley, D. F.


    The first excited electronic state (S1) vibrational dynamics of aniline(Ar)1 and aniline(CH4)1 van der Waals (vdW) clusters have been studied using molecular jet and time resolved emission spectroscopic techniques. The rates of intramolecular vibrational energy redistribution (IVR) and vibrational predissociation (VP) as functions of vibrational energy are reported for both clusters. For vibrational energy in excess of the cluster binding energy, both clusters are observed to dissociate. The dispersed emission spectra of these clusters demonstrate that aniline(Ar)1 dissociates to all energetically accessible bare molecule states and that aniline(CH4)1 dissociates selectively to only the bare molecule vibrationless state. The emission kinetics show that in the aniline(Ar)1 case, the initially excited states have nanosecond lifetimes, and intermediate cluster states have very short lifetimes. In contrast, the initially excited aniline(CH4)1 states and other intermediate vibrationally excited cluster states are very short lived (golden rule, and the density of vdW vibrational states is the most important factor in determining the relative [aniline(Ar)1 vs aniline(CH4)1] rates of IVR; (2) IVR among the vdW modes is rapid; and (3) VP rates can be calculated by a restricted vdW mode phase space Rice-Ramsberger-Kassel-Marcus theory. Since the density of vdW states is three orders of magnitude greater for aniline(CH4)1 than aniline(Ar)1 at 700 cm-1, the model predicts that IVR is slow and rate limiting in aniline(Ar)1, whereas VP is slow and rate limiting in aniline(CH4)1. The agreement of these predictions with the experimental results is very good and is discussed in detail.

  13. Balancing the Societal Dimensions of Venezuela and Colombia through the Amnesty, Reconciliation, and Reintegration (AR2) Process (United States)


    fractured society’s success in the amnesty, reconciliation, and reintegration (AR2) process. In Venezuela, there remains a fractured political system...Balancing the Societal Dimensions of Venezuela and Colombia through the Amnesty, Reconciliation, and Reintegration (AR2) Process A Monograph by... Reintegration (AR2) Process 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 6. AUTHOR(S) Ngo, Danielle J., Major, USA 5f. WORK

  14. Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance. (United States)

    Qiu, Yanyan; Sui, Xianxian; Zhan, Yongkun; Xu, Chen; Li, Xiaobo; Ning, Yanxia; Zhi, Xiuling; Yin, Lianhua


    Non-alcoholic fatty liver disease (NAFLD) covers a wide spectrum of liver pathology. Intracellular lipid accumulation is the first step in the development and progression of NAFLD. Steroidogenic acute regulatory protein (StAR) plays an important role in the synthesis of bile acid and intracellular lipid homeostasis and cholesterol metabolism. We hypothesize that StAR is involved in non-alcoholic fatty liver disease (NAFLD) pathogenesis. The hypothesis was identified using free fatty acid (FFA)-overloaded NAFLD in vitro model and high-fat diet (HFD)-induced NAFLD mouse model transfected by recombinant adenovirus encoding StAR (StAR). StAR expression was also examined in pathology samples of patients with fatty liver by immunohistochemical staining. We found that the expression level of StAR was reduced in the livers obtained from fatty liver patients and NAFLD mice. Additionally, StAR overexpression decreased the levels of hepatic lipids and maintained the hepatic glucose homeostasis due to the activation of farnesoid x receptor (FXR). StAR overexpression attenuated the impairment of insulin signaling in fatty liver. This protective role of StAR was owing to a reduction of intracellular diacylglycerol levels and the phosphorylation of PKCε. Furthermore, FXR inactivation reversed the observed beneficial effects of StAR. The present study revealed that StAR overexpression can reduce hepatic lipid accumulation, regulate glucose metabolism and attenuate insulin resistance through a mechanism involving the activation of FXR. Our study suggests that StAR may be a potential therapeutic target for NAFLD. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases. (United States)

    Lavysh, Daria; Sokolova, Maria; Slashcheva, Marina; Förstner, Konrad U; Severinov, Konstantin


    Bacteriophage AR9 is a recently sequenced jumbo phage that encodes two multisubunit RNA polymerases. Here we investigated the AR9 transcription strategy and the effect of AR9 infection on the transcription of its host, Bacillus subtilis Analysis of whole-genome transcription revealed early, late, and continuously expressed AR9 genes. Alignment of sequences upstream of the 5' ends of AR9 transcripts revealed consensus sequences that define early and late phage promoters. Continuously expressed AR9 genes have both early and late promoters in front of them. Early AR9 transcription is independent of protein synthesis and must be determined by virion RNA polymerase injected together with viral DNA. During infection, the overall amount of host mRNAs is significantly decreased. Analysis of relative amounts of host transcripts revealed notable differences in the levels of some mRNAs. The physiological significance of up- or downregulation of host genes for AR9 phage infection remains to be established. AR9 infection is significantly affected by rifampin, an inhibitor of host RNA polymerase transcription. The effect is likely caused by the antibiotic-induced killing of host cells, while phage genome transcription is solely performed by viral RNA polymerases.IMPORTANCE Phages regulate the timing of the expression of their own genes to coordinate processes in the infected cell and maximize the release of viral progeny. Phages also alter the levels of host transcripts. Here we present the results of a temporal analysis of the host and viral transcriptomes of Bacillus subtilis infected with a giant phage, AR9. We identify viral promoters recognized by two virus-encoded RNA polymerases that are a unique feature of the phiKZ-related group of phages to which AR9 belongs. Our results set the stage for future analyses of highly unusual RNA polymerases encoded by AR9 and other phiKZ-related phages. Copyright © 2017 Lavysh et al.

  16. Mutual Neutralization of Atomic Rare-Gas Cations (Ne+, Ar+, Kr+, Xe+) with Atomic Halide Anions (Cl-, Br-, I-) (United States)


    gas cations (Ne+, Ar+, Kr+, Xe+) with halide anions (Cl−, Br−, I−), comprising both mutual neutralization (MN) and transfer ionization. No rate...OF CHEMICAL PHYSICS 140, 044304 (2014) Mutual neutralization of atomic rare-gas cations (Ne+, Ar+, Kr+, Xe+) with atomic halide anions (Cl−, Br−, I... cations (Ne+, Ar+, Kr+, Xe+) with halide anions (Cl−, Br−, I−), comprising both mutual neutralization (MN) and transfer ionization. No rate coefficients

  17. Shorter CAG repeat in the AR gene is associated with atypical hyperplasia and breast carcinoma

    DEFF Research Database (Denmark)

    De Abreu, Francine Blumental; Pirolo, Leandro Júnior; Canevari, Renata de Azevedo


    BACKGROUND: Previous reports into the role of [CAG]n repeat lengths in the androgen receptor (AR) gene indicate that these may play an important part in the development and progression of breast cancer, however, knowledge regarding benign breast lesions is limited. PATIENTS AND METHODS: PCR......-based GeneScan analysis was used to investigate the [CAG]n repeat length at exon 1 of the AR gene in 59 benign breast lesions (27 fibroadenomas, 18 atypical hyperplasias, and 14 hyperplasias without atypia) and 54 ductal breast carcinomas. Seventy-two cancer-free women were used as a control group...

  18. Monolithic light guide optics enabling new user experience for see-through AR glasses (United States)

    Sarayeddline, K.; Mirza, K.; Benoit, P.; Hugel, X.


    This paper describes the performances of mold light guide based see-through optics for the production of AR glasses for commercial and professional applications. A monolithic thin mold light guide with surface structure mirror array extracts and project bright and large virtual image into the user eye of sight. The light guide thin form factor allows a new user experience with two possible positions for the virtual image in front of the user eye. A wireless AR glasses based on this concept will be described and demonstrated. A comparison with others light guide based technologies in term of Safety, Brightness efficiency and form factor will be presented and discussed.

  19. AR Based App for Tourist Attraction in ESKİ ÇARŞI (Safranbolu

    Directory of Open Access Journals (Sweden)

    M. Polat


    Full Text Available This research is dealing with 3D modeling of historical and heritage landmarks of Safranbolu that are registered by UNESCO. This is an Augmented Reality (AR based project in order to trigger virtual three-dimensional (3D models, cultural music, historical photos, artistic features and animated text information. The aim is to propose a GIS-based approach with these features and add to the system as attribute data in a relational database. The database will be available in an AR-based application to provide information for the tourists.

  20. Complement component C3aR constitutes a novel regulator for chick eye morphogenesis. (United States)

    Grajales-Esquivel, Erika; Luz-Madrigal, Agustin; Bierly, Jeffrey; Haynes, Tracy; Reis, Edimara S; Han, Zeyu; Gutierrez, Christian; McKinney, Zachary; Tzekou, Apostolia; Lambris, John D; Tsonis, Panagiotis A; Del Rio-Tsonis, Katia


    Complement components have been implicated in a wide variety of functions including neurogenesis, proliferation, cell migration, differentiation, cancer, and more recently early development and regeneration. Following our initial observations indicating that C3a/C3aR signaling induces chick retina regeneration, we analyzed its role in chick eye morphogenesis. During eye development, the optic vesicle (OV) invaginates to generate a bilayer optic cup (OC) that gives rise to the retinal pigmented epithelium (RPE) and neural retina. We show by immunofluorescence staining that C3 and the receptor for C3a (the cleaved and active form of C3), C3aR, are present in chick embryos during eye morphogenesis in the OV and OC. Interestingly, C3aR is mainly localized in the nuclear compartment at the OC stage. Loss of function studies at the OV stage using morpholinos or a blocking antibody targeting the C3aR (anti-C3aR Ab), causes eye defects such as microphthalmia and defects in the ventral portion of the eye that result in coloboma. Such defects were not observed when C3aR was disrupted at the OC stage. Histological analysis demonstrated that microphthalmic eyes were unable to generate a normal optic stalk or a closed OC. The dorsal/ventral patterning defects were accompanied by an expansion of the ventral markers Pax2, cVax and retinoic acid synthesizing enzyme raldh-3 (aldh1a3) domains, an absence of the dorsal expression of Tbx5 and raldh-1 (aldh1a1) and a re-specification of the ventral RPE to neuroepithelium. In addition, the eyes showed overall decreased expression of Gli1 and a change in distribution of nuclear β-catenin, suggesting that Shh and Wnt pathways have been affected. Finally, we observed prominent cell death along with a decrease in proliferating cells, indicating that both processes contribute to the microphthalmic phenotype. Together our results show that C3aR is necessary for the proper morphogenesis of the OC. This is the first report implicating C3aR in

  1. Optimizacija trnsporta v podjetju Avtoprevozništvo Vičar Ivan s.p.


    Vičar, Aljaž


    OPTIMIZACIJA TRANSPORTA V AVTOPREVOZNIŠTVU VIČAR IVAN s. p. V diplomski nalogi Optimizacija transporta v Avtoprevozništvu Vičar Ivan s.p., smo reševal problematiko optimizacije transporta. V teoretičnem delu smopredstavili temeljne pojme, ki so pomembni za lažje razumevanje diplomskega dela. Osredotočili smo se predvsem na stroške, ki nastajajo ob opravljanju osnovne dejavnosti obravnavanega podjetja. Po teoretičnem delu smo vse skupaj preizkusil še v praksi. V diplomskem delu smo ...

  2. Atomic structure dependence of nonsequential double ionization of He, Ne and Ar in strong laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Jesus, V L B de; Feuerstein, B; Zrost, K; Fischer, D; Rudenko, A; Afaneh, F; Schroeter, C D; Moshammer, R; Ullrich, J [Max-Planck-Institut fuer Kernphysik, D-69029 Heidelberg (Germany)


    The ion momentum spectra for nonsequential double ionization of rare gases (He, Ne and Ar) in 23 fs 795 nm laser pulses were measured in the intensity range 0.075-1.25 PW cm{sup -2}. In the studies published, confusing differences in the shape of momentum distributions among different targets are consistently explained within a recollision scenario: excitation during recollision plus subsequent field ionization, not implemented in most theoretical approaches, evidently plays a decisive role for He and Ar nonsequential double ionization whereas it plays only a minor role for Ne. (letter to the editor)

  3. Compostos carbonílicos no ar em ambientes de trabalho de carvoarias na Bahia


    Carvalho, Albertinho Barreto de


    Este trabalho foi realizado com os seguintes objetivos: apresentar uma metodologia analítica aplicável à determinação de compostos carbonílicos (CC) em fase vapor, em amostras estacionárias e pessoais coletadas em ambientes de trabalho de carvoarias; determinar o perfil dos CC presentes no ar inalado pelos trabalhadores e; quantificar os CC no ar, na fase vapor, em locais de trabalho e na zona respiratória de trabalhadores carvoeiros. Os trabalhos de campo foram realizados em q...

  4. ServAR: An augmented reality tool to guide the serving of food. (United States)

    Rollo, Megan E; Bucher, Tamara; Smith, Shamus P; Collins, Clare E


    Accurate estimation of food portion size is a difficult task. Visual cues are important mediators of portion size and therefore technology-based aids may assist consumers when serving and estimating food portions. The current study evaluated the usability and impact on estimation error of standard food servings of a novel augmented reality food serving aid, ServAR. Participants were randomised into one of three groups: 1) no information/aid (control); 2) verbal information on standard serving sizes; or 3) ServAR, an aid which overlayed virtual food servings over a plate using a tablet computer. Participants were asked to estimate the standard serving sizes of nine foods (broccoli, carrots, cauliflower, green beans, kidney beans, potato, pasta, rice, and sweetcorn) using validated food replicas. Wilcoxon signed-rank tests compared median served weights of each food to reference standard serving size weights. Percentage error was used to compare the estimation of serving size accuracy between the three groups. All participants also performed a usability test using the ServAR tool to guide the serving of one randomly selected food. Ninety adults (78.9% female; a mean (95%CI) age 25.8 (24.9-26.7) years; BMI 24.2 (23.2-25.2) kg/m 2 ) completed the study. The median servings were significantly different to the reference portions for five foods in the ServAR group, compared to eight foods in the information only group and seven foods for the control group. The cumulative proportion of total estimations per group within ±10%, ±25% and ±50% of the reference portion was greater for those using ServAR (30.7, 65.2 and 90.7%; respectively), compared to the information only group (19.6, 47.4 and 77.4%) and control group (10.0, 33.7 and 68.9%). Participants generally found the ServAR tool easy to use and agreed that it showed potential to support optimal portion size selection. However, some refinements to the ServAR tool are required to improve the user experience. Use of the

  5. Spatially resolved x-ray spectroscopy investigation of femtosecond laser irradiated Ar clusters. (United States)

    Junkel-Vives, G C; Abdallah, J; Auguste, T; D'Oliveira, P; Hulin, S; Monot, P; Dobosz, S; Faenov, A Ya; Magunov, A I; Pikuz, T A; Skobelev, I Yu; Boldarev, A S; Gasilov, V A


    High temperature plasmas have been created by irradiating Ar clusters with high intensity 60-fs laser pulses. Detailed spectroscopic analysis of spatially resolved, high resolution x-ray data near the He(alpha) line of Ar is consistent with a two-temperature collisional-radiative model incorporating the effects of highly energetic electrons. The results of the spectral analysis are compared with a theoretical hydrodynamic model of cluster production, as well as interferometric data. The plasma parameters are notably uniform over one Rayleigh length (600 microm).

  6. An influence of androgen receptor (AR gene СAG-polymorphism on spermatogenesis in infertile men

    Directory of Open Access Journals (Sweden)

    V. B. Chernykh


    Full Text Available We analyzed the results of semen examination in 200 infertile men with various numbers of GAG-repeats in the exon 1 of the androgen receptor (AR gene. The number of repeats ranged from 7 to 31, the average number of repeats was 22.2 ± 1.6, with the most common variant (13 % present 21 repeats. Our findings confirm that of AR gene СAG-polymorphism can an effect on sperm parameters and male fertility. The spermatogenesis can be impaired in infertile men with “short” CAG-repeats not less than with “long” CAG-repeats.

  7. Optimización del proceso de secado de arándanos por infrarrojos.




    Se estudiará el método de secado por infrarrojos (con o sin pre-tratamiento de remoción química de la piel) y su influencia en algunos parámetros de calidad en arándanos buscando la optimización del proceso de secado. Arándanos de las variedades O'Neal, Misty, Reveille, Georgia Gem y Blue Cuinex de la Región de Salto Grande (República Argentina) serán deshidratados inmediatamente de su cosecha mediante un secador asistido por infrarrojo lejano (CIR Los factores que se consideran son: t...


    Directory of Open Access Journals (Sweden)

    Muhammad Nanda Kurniawan


    Full Text Available Abstract In this research, Parrot AR.Drone as an Unmanned Aerial Vehicle (UAV was used to track an object from above. Development of this system utilized some functions from OpenCV library and Robot Operating System (ROS. Techniques that were implemented in the system are image processing al-gorithm (Centroid-Contour Distance (CCD, feature extraction algorithm (Principal Component Analysis (PCA and an artificial neural network algorithm (Generalized Learning Vector Quantization (GLVQ. The final result of this research is a program for AR.Drone to track a moving object on the floor in fast response time that is under 1 second.

  9. Molecular dynamics study on the vapor-liquid interface of Ar-Ne mixtures (United States)

    Yamaguchi, Kyohei; Inaba, Masashi; Yano, Takeru


    An interface between an Ar-Ne gas mixture and its own liquid mixture in an equilibrium state has been studied by molecular dynamics simulation with 12-6 Lennard-Jones potential and Lorentz-Berthelot mixing rule. As a result, we accurately evaluate macroscopic variables, and carefully discuss the difference between the stress defined by Bearman and Kirkwood (1958) and that defined by the method of control surface. The result shows that the stress defined by Bearman and Kirkwood is not suitable for describing the detailed structure of vapor-liquid interface of Ar-Ne mixture.

  10. Limit on the radiative neutrinoless double electron capture of {sup 36}Ar from GERDA Phase I

    Energy Technology Data Exchange (ETDEWEB)

    Agostini, M.; Balata, M.; D' Andrea, V.; Di Vacri, A.; Junker, M.; Laubenstein, M. [INFN Laboratori Nazionali del Gran Sasso and Gran Sasso Science Institute, Assergi (Italy); Allardt, M.; Domula, A.; Lehnert, B.; Schneider, B.; Wester, T.; Wilsenach, H.; Zuber, K. [Technische Universitaet Dresden, Institut fuer Kern- und Teilchenphysik, Dresden (Germany); Bakalyarov, A.M.; Belyaev, S.T.; Lebedev, V.I.; Zhukov, S.V. [National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Barabanov, I.; Bezrukov, L.; Doroshkevich, E.; Fedorova, O.; Gurentsov, V.; Kazalov, V.; Kuzminov, V.V.; Lubsandorzhiev, B.; Moseev, P.; Selivanenko, O.; Veresnikova, A.; Yanovich, E. [Institute for Nuclear Research of the Russian Academy of Sciences, Moscow (Russian Federation); Barros, N. [Technische Universitaet Dresden, Institut fuer Kern- und Teilchenphysik, Dresden (Germany); University of Pennsylvania, Philadelphia, PA (United States); Baudis, L.; Benato, G.; Kish, A.; Miloradovic, M.; Mingazheva, R.; Walter, M. [Physik Institut der Universitaet Zuerich, Zurich (Switzerland); Bauer, C.; Hakenmueller, J.; Heisel, M.; Heusser, G.; Hofmann, W.; Kihm, T.; Kirsch, A.; Knoepfle, K.T.; Lindner, M.; Maneschg, W.; Salathe, M.; Schreiner, J.; Schwingenheuer, B.; Simgen, H.; Smolnikov, A.; Stepaniuk, M.; Wagner, V.; Wegmann, A. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Bellotti, E. [Universita Milano Bicocca, Dipartimento di Fisica, Milan (Italy); INFN Milano Bicocca, Milan (Italy); Belogurov, S.; Kornoukhov, V.N. [Institute for Nuclear Research of the Russian Academy of Sciences, Moscow (Russian Federation); Institute for Theoretical and Experimental Physics NRC ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Bettini, A.; Brugnera, R.; Garfagnini, A.; Medinaceli, E.; Sada, C.; Sturm, K. von [Dipartimento di Fisica e Astronomia dell' Universita di Padova, Padua (Italy); INFN Padova, Padua (Italy); Bode, T.; Csathy, J.J.; Lazzaro, A.; Schoenert, S.; Wiesinger, C. [Technische Universitaet Muenchen, Physik Department and Excellence Cluster Universe, Munich (Germany); Borowicz, D. [Jagiellonian University, Institute of Physics, Krakow (Poland); Joint Institute for Nuclear Research, Dubna (Russian Federation); Brudanin, V.; Egorov, V.; Kochetov, O.; Nemchenok, I.; Rumyantseva, N.; Zhitnikov, I.; Zinatulina, D. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Caldwell, A.; Gooch, C.; Kneissl, R.; Liao, H.Y.; Majorovits, B.; Palioselitis, D.; Schulz, O.; Vanhoefer, L. [Max-Planck-Institut fuer Physik, Munich (Germany); Cattadori, C.; Salamida, F. [INFN Milano Bicocca, Milan (Italy); Chernogorov, A.; Demidova, E.V.; Kirpichnikov, I.V.; Vasenko, A.A. [Institute for Theoretical and Experimental Physics NRC ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Falkenstein, R.; Freund, K.; Grabmayr, P.; Hegai, A.; Jochum, J.; Schmitt, C.; Schuetz, A.K. [Eberhard Karls Universitaet Tuebingen, Physikalisches Institut, Tuebingen (Germany); Frodyma, N.; Misiaszek, M.; Panas, K.; Pelczar, K.; Wojcik, M.; Zuzel, G. [Jagiellonian University, Institute of Physics, Krakow (Poland); Gangapshev, A. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Institute for Nuclear Research of the Russian Academy of Sciences, Moscow (Russian Federation); Gusev, K. [Joint Institute for Nuclear Research, Dubna (Russian Federation); National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Technische Universitaet Muenchen, Physik Department and Excellence Cluster Universe, Munich (Germany); Hemmer, S.; Lippi, I.; Stanco, L. [INFN Padova, Padua (Italy); Hult, M.; Lutter, G. [European Commission, JRC-Geel, Geel (Belgium); Inzhechik, L.V. [Institute for Nuclear Research of the Russian Academy of Sciences, Moscow (Russian Federation); Moscow Institute of Physics and Technology, Moscow (Russian Federation); Klimenko, A. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); International University for Nature, Society and Man ' ' Dubna' ' , Dubna (Russian Federation); Lubashevskiy, A. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Macolino, C. [INFN Laboratori Nazionali del Gran Sasso and Gran Sasso Science Institute, Assergi (Italy); LAL, CNRS/IN2P3, Universite Paris-Saclay, Orsay (France); Pandola, L. [INFN Laboratori Nazionali del Sud, Catania (Italy); Pullia, A.; Riboldi, S. [Universita degli Studi di Milano, Dipartimento di Fisica, Milan (Italy); INFN Milano (Italy); Shirchenko, M. [Joint Institute for Nuclear Research, Dubna (Russian Federation); National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Collaboration: GERDA collaboration


    Neutrinoless double electron capture is a process that, if detected, would give evidence of lepton number violation and the Majorana nature of neutrinos. A search for neutrinoless double electron capture of {sup 36}Ar has been performed with germanium detectors installed in liquid argon using data from Phase I of the GERmanium Detector Array (Gerda) experiment at the Gran Sasso Laboratory of INFN, Italy. No signal was observed and an experimental lower limit on the half-life of the radiative neutrinoless double electron capture of {sup 36}Ar was established: T{sub 1/2} > 3.6 x 10{sup 21} years at 90% CI. (orig.)

  11. Energy dependent stereodynamics of the Ne($^3$P$_2$)+Ar reaction


    Gordon, Sean D. S.; Zou, Junwen; Tanteri, Silvia; Jankunas, Justin; Osterwalder, Andreas


    The stereodynamics of the Ne($^3$P$_2$)+Ar Penning and Associative ionization reactions have been studied using a crossed molecular beam apparatus. The experiment uses a curved magnetic hexapole to polarise the Ne($^3$P$_2$) which is then oriented with a shaped magnetic field in the region where it intersects with a beam of Ar($^1$S). The ratios of Penning to associative ionization were recorded over a range of collision energies from 320 cm$^{-1}$ to 500 cm$^{-1}$ and the data was used to ob...

  12. XeCl Avalanche discharge laser employing Ar as a diluent (United States)

    Sze, Robert C.


    A XeCl avalanche discharge exciplex laser which uses a gaseous lasing starting mixture of: (0.2%-0.4% chlorine donor/2.5%-10% Xe/97.3%-89.6% Ar). The chlorine donor normally comprises HCl but can also comprise CCl.sub.4 BCl.sub.3. Use of Ar as a diluent gas reduces operating pressures over other rare gas halide lasers to near atmospheric pressure, increases output lasing power of the XeCl avalanche discharge laser by 30% to exceed KrF avalanche discharge lasing outputs, and is less expensive to operate.

  13. First {40Ar }/{39Ar } dating on early pliocene to plio-pleistocene magmatic events of the Afar — Republic of Djibouti (United States)

    Zumbo, Vilma; Féraud, Gilbert; Vellutini, Pierre; Piguet, Patrick; Vincent, Joëlle


    Many detailed geochemical, geophysical and structural studies have been made in the Afar — Republic of Djibuti, but its geologic evolution remains poorly constrained in time. To improve the understanding of the timing of significant geologic events, we analyzed by the {40Ar }/{39Ar } stepwise heating method twenty-one samples (plagioclases, sanidines and whole rocks) carefully selected from each main volcanic formation. Fifteen plateau ages were obtained, whereas the other samples revealed alteration processes and/or excess argon components. The oldest reliable age is obtained on an altered lava flow from the Ali Sabieh formation, giving a plateau age at 23.6 ± 0.5 Ma. The dyke swarm of the Ali Sabieh area gave homogeneous ages of 17-16 Ma on dykes of different compositions (rhyolitic and basaltic) and orientations (N-S, N140-160 °E and N35 °E), similar to those obtained on some dyke swarms of Southern Yemen. Two plateau ages obtained on two lava flows from the bottom and the top of the Mablas series seem to indicate a period of activity slightly shorter (15.4 ± 0.3 to 11.8 ± 0.6 Ma) than that deduced from conventional {K}/{Ar} data (16.3 to 9.7 Ma). Plateau ages from 2.0 ± 0.2 to 1.00 ± 0.09 Ma were obtained on lava flows from different locations of the Stratoid series. They are concordant with previous conventional {K}/{Ar} data obtained by Courtillot and co-workers, but ages corresponding to the earliest part of the 4-1 Ma period, generally accepted for the whole Stratoid series, were not found. Precise plateau ages ranging from 1.03 ± 0.03 Ma to 0.25 ± 0.02 Ma were obtained on lava flows and intrusions from the Asal and Manda Inakir rifts and the Moussa Ali volcano. These new data slightly modify parts of the generally accepted period of emplacement of the main volcanic units of Afar, and show that some previous conventional K-Ar ages may be affected by argon loss (alteration) and/or excess argon.

  14. Comparison of vacuum ultra-violet emission of Ar/CF4 and Ar/CF3I capacitively coupled plasmas (United States)

    Zotovich, A.; Proshina, O.; el Otell, Z.; Lopaev, D.; Rakhimova, T.; Rakhimov, A.; de Marneffe, J.-F.; Baklanov, M. R.


    Spectra in the vacuum-ultra violet range (VUV, 30 nm-200 nm) as well as in the ultra-violet(UV) and visible ranges (UV+vis, 200 nm-800 nm) were measured from Ar/CF3I and Ar/CF4 discharges. The discharges were generated in an industrial 300 mm capacitively coupled plasma source with 27 MHz radio-frequency power. It was seen that the measured spectra were strongly modified. This is mainly due to absorption, especially by CF3I, and Ar self-trapping along the line of sight, towards the detector and in the plasma itself. The estimated unabsorbed VUV spectra were revealed from the spectra of mixtures with low fluorocarbon gas content by means of normalization with unabsorbed I* emission, at 206 nm, and CF2\\ast band (1B1(0,v‧,0){{\\to}1} A1(0,{{\\text{v}}\\prime \\prime} ,0)) emission between 230 nm and 430 nm. Absolute fluences of UV CF2\\ast emission were derived using hybrid 1-dimensional (1D) particle-in-cell (PIC) Monte-Carlo (MC) model calculations. Absolute calibration of the VUV emission was performed using these calculated values from the model, which has never been done previously for real etch conditions in an industrial chamber. It was seen that the argon resonant lines play a significant role in the VUV spectra. These lines are dominant in the case of etching recipes close to the standard ones. The restored unabsorbed spectra confirm that replacement of conventional CF4 etchant gas with CF3I in low-k etching recipes leads to an increase in the overall VUV emission intensity. However, emission from Ar exhibited the most intense peaks. Damage to low-k SiCOH glasses by the estimated VUV was calculated for blanket samples with pristine k-value of 2.2. The calculations were then compared with Fourier transform infrared (FTIR) data for samples exposed to the similar experimental conditions in the same reactor. It was shown that Ar emission plays the most significant role in VUV-induced damage.

  15. Upper Mammoth Polarity Transition Recorded in the Pu'u Kualakauila volcanic sequence, Wai'anae Volcano, Oahu, Hawaii USA: Paleomagnetic and 40Ar/39Ar Evidence (United States)

    Lau, J. K.; Herrero-Bervera, E.; Jicha, B.; Valet, J.


    New paleomagnetic measurements, coupled with Argon-Argon (40Ar/39Ar) radioisotopic dating, are revolutionizing our understanding of the geodynamo by providing detailed terrestrial lava records of the short-term behavior of the paleomagnetic field. As part of an investigation of the Wai'anae Volcano, Oahu, and the short-term behavior of the geomagnetic field, we have sampled a long volcanic section located on the volcano's collapsed flank at a locality known as Pu'u Kaulakauila. Prior paleomagnetic investigations of the Kamaile'unu Volcanic Series (i.e. Herrero-Bervera and Valet, 2005) revealed transitional directions. The silicic composition of lava flows, easy access, and close geographical proximity to K-Ar dated flows made this newly studied 214-m thick sequence of flows an excellent candidate for detailed paleomagnetic analysis. At least eight samples, collected from each of 45 successive flow sites, were stepwise demagnetized by both alternating field (5 mT to 100 mT) and thermal (from 28 °C to 575-650 °C) methods. Mean directions were obtained by principal component analysis. All samples yielded a strong and stable ChRM trending towards the origin of vector demagnetization diagrams based on seven or more demagnetization steps, with thermal and AF results differing insignificantly. Low-field susceptibility vs. temperature (k-T) analysis conducted on individual lava flows indicated approximately half with reversible curves. Curie point determinations from these analyses revealed a temperature close to or equal to 580 °C, indicative of almost pure magnetite ranging from single domain (SD) to pseudosingle domain (PSD) grain sizes for most of the flows. The mean directions of magnetization of the entire section sampled indicate a reversed polarity, with ˜10 m of the section characterized by excursional directions (5 lava flows). Thellier-Coe and microwave paleointensities determinations of these flows indicate a substantial decrease of the absolute

  16. Confirming the key role of Ar+ ion bombardment in the growth feature of nanostructured carbon materials by PECVD (United States)

    Liu, Yulin; Lin, Jinghuang; Jia, Henan; Chen, Shulin; Qi, Junlei; Qu, Chaoqun; Cao, Jian; Feng, Jicai; Fei, Weidong


    In order to confirm the key role of Ar+ ion bombardment in the growth feature of nanostructured carbon materials (NCMs), here we report a novel strategy to create different Ar+ ion states in situ in plasma enhanced chemical vapor deposition (PECVD) by separating catalyst film from the substrate. Different bombardment environments on either side of the catalyst film were created simultaneously to achieve multi-layered structural NCMs. Results showed that Ar+ ion bombardment is crucial and complex for the growth of NCMs. Firstly, Ar+ ion bombardment has both positive and negative effects on carbon nanotubes (CNTs). On one hand, Ar+ ions can break up the graphic structure of CNTs and suppress thin CNT nucleation and growth. On the other hand, Ar+ ion bombardment can remove redundant carbon layers on the surface of large catalyst particles which is essential for thick CNTs. As a result, the diameter of the CNTs depends on the Ar+ ion state. As for vertically oriented few-layer graphene (VFG), Ar+ ions are essential and can even convert the CNTs into VFG. Therefore, by combining with the catalyst separation method, specific or multi-layered structural NCMs can be obtained by PECVD only by changing the intensity of Ar+ ion bombardment, and these special NCMs are promising in many fields.

  17. Synchrotron X-Ray Study of Melting in Submonolayer Ar and other Rare-Gas Films on Graphite

    DEFF Research Database (Denmark)

    McTague, J. P.; Als-Nielsen, Jens Aage; Bohr, Jakob


    Synchrotron x-ray diffraction studies of the (10) peak of Ar on the (001) surface of ZYX graphite show a sharp but continuous broadening of the Bragg peak with increasing temperature. Below a coverage of ∼ 1 Ar atom per six surface carbon atoms (ρ=1) the onset of this transition occurs at a cover......Synchrotron x-ray diffraction studies of the (10) peak of Ar on the (001) surface of ZYX graphite show a sharp but continuous broadening of the Bragg peak with increasing temperature. Below a coverage of ∼ 1 Ar atom per six surface carbon atoms (ρ=1) the onset of this transition occurs...

  18. Affinity chromatography of alpha/sub 2/-adrenergic receptors (. cap alpha. /sub 2/AR) from pig cerebral cortex

    Energy Technology Data Exchange (ETDEWEB)

    Repaske, M.G.; Limbird, L.E.


    A high capacity, ..cap alpha../sub 2/AR-selective affinity resin (YOH. ag) has been prepared by coupling yohimbinic acid to diaminodipropylamine agarose with 1,3 dicyclohexylcarbodiimide. Unreacted amino groups on the agarose matrix are blocked subsequently by acetylation. One volume of YOH. ag adsorbs 75% of the ..cap alpha../sub 2/AR from 50 volumes of digitonin-solubilized preparation containing 0.2 pmol ..cap alpha../sub 2/AR/mg protein. Digitonin-solubilized preparations are derived from cholate extracts of porcine cerebral cortex containing approx. 0.075 pmol ..cap alpha../sub 2/AR/mg protein. Adsorption of ..cap alpha../sub 2/AR to YOH. ag is selective and thus is blocked by the ..cap alpha..-adrenergic antagonist phentolamine. Adsorbed ..cap alpha../sub 2/AR are eluted with 10 phentolamine (20% yield) after removal of non-related proteins with NaCl gradients. Following hydroxylapatite chromatography to concentrate ..cap alpha..''AR and to remove phentolamine, the ..cap alpha..AR is present at 200-400 pmol/mg protein, assayed using sub-saturating concentrations of (/sup 3/H)-yohimbine. (It is estimated that the specific activity of a homogeneous ..cap alpha../sub 2/AR preparation would be 12,000-16,000 pmol/mg protein.) The availability of large quantities of cortical ..cap alpha../sub 2/AR and a resin easily prepared from commercially-supplied reagents suggests that purification of quantities of ..cap alpha../sub 2/AR sufficient for subsequent biochemical studies is feasible.

  19. Optical characteristics of a RF DBD plasma jet in various Ar/O2 ...

    Indian Academy of Sciences (India)

    Using the optical emission spectrum analysis of the RF plasma jet, the excitation temperature is determined based on the Boltzmann plot method. The electron density in the plasma medium of the RF plasma jet is obtained by the Stark broadening of the hydrogen Balmer H β . It is mostly seen that, the radiation intensity of Ar ...

  20. Videokunstnik Mark Raidpere tõi Ars Fennica auhinna Eestisse / Ants Juske

    Index Scriptorium Estoniae

    Juske, Ants, 1956-2016


    Auhinna andis 28. veebruaril Mark Raidperele üle Soome riigipea Tarja Halonen. Lühidalt Ars Fennica kunstiauhinnast. Preemia nominentide - Maria Duncker, Tea Mäkipää, Seppo Renvall, Katrina Neiburga, Mark Raidpere - tööde näitus on avatud Kumu Kunstimuuseumis 26. aprillini


    NARCIS (Netherlands)


    We present electron spectra resulting from collisions of bare ions N-15(7+) and C-13(6+) on Ar and the charge state distribution of target ions resulting from C-13(6+)-Xe collisions. From both type of experiments we find evidence that electron capture accompanied by target excitation is an important

  2. Partial sums of lagged cross-products of AR residuals and a test for white noise

    NARCIS (Netherlands)

    de Gooijer, J.G.


    Partial sums of lagged cross-products of AR residuals are defined. By studying the sample paths of these statistics, changes in residual dependence can be detected that might be missed by statistics using only the total sum of cross-products. Also, a test statistic for white noise is proposed. It is

  3. CALiPER Application Summary Report 17. LED AR111 and PAR36 Lamps

    Energy Technology Data Exchange (ETDEWEB)



    Report 17 analyzes the performance of a group of six LED products labeled as AR111 lamps. Results indicate that this product category lags behind other types of directional LED lamps but may perform acceptably in some applications and provide some energy savings.

  4. 77 FR 16800 - Radio Broadcasting Services; Dermott, AR, and Cleveland, MS (United States)


    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Dermott, AR, and Cleveland, MS AGENCY: Federal... 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications Commission. Nazifa Sawez, Assistant... Commission requests comment on a petition filed by Delta Radio Network, LLC, proposing to amend the Table of...

  5. USDA-ARS extension activities in medical, veterinary and urban entomology (United States)

    Within the USDA Agricultural Research Service (USDA-ARS), National Program 104 conducts research on veterinary, medical, and urban entomology. The goal of this program is to develop more effective methods of preventing or suppressing insects, ticks, and mites that affect animal and human well-being....

  6. Whole-genome sequence of Escherichia coli serotype O157:H7 strain B6914-ARS (United States)

    Escherichia coli serotype O157:H7 strain B6914-MS1 is a Shiga toxin-deficient human fecal isolate obtained by the Centers for Disease Control and Prevention that has been used extensively in applied research studies. Here we report the genome sequence of strain B6914-ARS, a B6914-MS1 clone that has ...

  7. Steric effects and quantum interference in the inelastic scattering of NO(X) plus Ar

    NARCIS (Netherlands)

    Nichols, B.; Chadwick, H.; Gordon, S.D.S.; Eyles, C.J.; Hornung, B.; Brouard, M.; Alexander, M.H.; Aoiz, F.J.; Gijsbertsen, A.; Stolte, S.


    Rotationally inelastic collisions of NO(X) with Ar are investigated in unprecedented detail using state-to-state, crossed molecular beam experiments. The NO(X) molecules are selected in the Ω = 0.5, j = 0.5, f state and then oriented such that either the 'N' or 'O' end of the molecule is directed

  8. Process isolation for ARMA(1,1) subsumed in errors following AR(1 ...

    African Journals Online (AJOL)

    Password, Remember me, or Register. DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT Subscription or Fee Access. Process isolation for ARMA(1,1) subsumed in errors following AR(1) process. D Eni. Abstract. No Abstract. International Journal of Natural and Applied Sciences Vol. 3 (4) 2007: pp. 471-478 ...

  9. On the parameter estimation of first order IMA model corrupted with AR

    African Journals Online (AJOL)

    On the parameter estimation of first order IMA model corrupted with AR (1) errors. D Eni, S A Mahmud. Abstract. No Abstract. Global Journal of Pure and Applied Physics Vol. 14 (1) 2008 pp. 115-120. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  10. Applying AR technology with a projector-camera system in a history museum (United States)

    Miyata, Kimiyoshi; Shiroishi, Rina; Inoue, Yuka


    In this research, an AR (augmented reality) technology with projector-camera system is proposed for a history museum to provide user-friendly interface and pseudo hands-on exhibition. The proposed system is a desktop application and designed for old Japanese coins to enhance the visitors' interests and motivation to investigate them. The size of the old coins are small to recognize their features and the surface of the coins has fine structures on both sides, so it is meaningful to show the reverse side and enlarged image of the coins to the visitors for enhancing their interest and motivation. The image of the reverse side of the coins is displayed based on the AR technology to reverse the AR marker by the user. The information to augment the coins is projected by using a data projector, and the information is placed nearby the coins. The proposed system contributes to develop an exhibition method based on the combinations of the real artifacts and the AR technology, and demonstrated the flexibility and capability to offer background information relating to the old Japanese coins. However, the accuracy of the detection and tracking of the markers and visitor evaluation survey are required to improve the effectiveness of the system.

  11. Ars Dictaminis Perverted: The Personal Solicitation E-Mail as a Genre (United States)

    Ross, Derek G.


    Phishing e-mails deceive individuals into giving out personal information which may then be utilized for identity theft. One particular type, the Personal Solicitation E-mail (PSE) mimics personal letters--modern perversions of "ars dictaminis" (the classical art of letter writing). In this article, I determine and discuss 19 appeals common to the…

  12. History and Current Research in the USDA-ARS Cotton Breeding Program at Stoneville, MS (United States)

    It has been more than 50 years since the USDA-ARS cotton breeding program was initiated at Stoneville, MS in the middle of last century. The mission of this program was established to promote profits for cotton growers and improve cotton production in the U.S. In early times, earliness was a top pri...

  13. Intrinsic efficiency and critical power deposition in the e-beam sustained Ar:Xe laser

    NARCIS (Netherlands)

    Botma, H.; Botma, H.; Peters, P.J.M.; Witteman, W.J.


    Experimental investigations on an e-beam sustained near infrared Ar:Xe laser have been carried out to determine the intrinsic efficiency at optimized conditions. A parametric study at different sustainer currents reveals a maximum output energy depending on current density. Up to 8 bar the optimized

  14. Potato-related research at USDA-ARS laboratories in Washington and Idaho (United States)

    Potato-related research currently being conducted at three USDA-ARS laboratories in Idaho and Washington is reviewed. Objectives of research programs at the Temperate Tree Fruit & Vegetable Research Unit (Wapato, WA), the Irrigated Agriculture Research and Extension Center (Prosser, WA), and the Sm...

  15. "Ars Electronica" "Next Sex", spermaralli ja vägistamine "kunstiloome strateegiana" / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-


    Festival Linzis 2.-7. IX. teemal "Inimene biotehnoloogilise reproduktsiooni ajastul". "Ars Electronica" keskuses meediakunsti püsinäitus "Museum of the Future". Konverentsist, pikemalt Randy Thornhilli ettekandest vägistamise evolutsioonibioloogiast, kunstiprojektidest. Ilmunud ka kogumikus "Ekraan kui membraan". Tartu, 2007, lk. 84-87

  16. Effect of adding Ar gas on the pulse height distribution of BF3-filled ...

    Indian Academy of Sciences (India)

    The dilution of BF3 with argon causes a decrease in detection efficiency, but the pulse height spectrum shows sharper peaks and more stable plateau characteristics than counters filled with pure BF3. The present investigations are under-taken to study the pulse height distribution and other important factors in BF3+Ar filled ...


    African Journals Online (AJOL)

    A. AR~OUREI) I)IVISIO~. I~ ITALY. WINTER '1944 - 1945. The period 20 - 23 October was the climax of the offensive, not only on 6 SA Armoured. Divisional sector, but on the front of the whole. Fifth Army. II US Corps had been attacking with great determination east of Route 65, and on 23 October 34 Division captured Mt.

  18. Anti-Retroviral Therapy Related Liver Injury (ARLI): A Series of 11 ...

    African Journals Online (AJOL)

    Objective: To describe anti-retroviral-related liver injury (ARLI) in HIV positive patients, their CD4+ cell counts, biochemical and viral markers and liver ultrasound. Design: Prospective, descriptive, consecutive entry study. Setting: Kisumu District Hospital liver clinic/medical outpatient clinic, Nairobi Rheumatology Clinic and ...

  19. Data of evolutionary structure change: 1AR5A-1EN6C [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available ce>KGLKK----GTTLQ >H ---- > ATOM...D> A 1AR5A KNMAPKGSAPERPT ...tryIDChain> LVLKG--DKLAV >EEEE -- EEEE...ence>LVWDPLGKRINT >EEEE EEEEe> AT...>H > ATOM 632 CA LYS A 80 40.102 17.348 55.570 1.00 13

  20. Acumulación de arsénico en el cultivo de habas (Vicia Faba

    Directory of Open Access Journals (Sweden)

    Francisco Prieto García


    Full Text Available La presencia de arsénico en aguas y suelos de Zimapán, en el estado de Hidalgo, México, causa que los cultivos de haba presenten concentraciones apreciables de dicho elemento. Los suelos evaluados presentaron texturas, conductividad, contenidos de N y de arsénico diferentes, pero resultados similares en pH, potencial redox, y contenido de materia orgánica. La elevada bioacumulación de arsénico en estos suelos fue directamente proporcional al tiempo de exposición. Las concentraciones de arsénico acumuladas más altas se obtuvieron en la raíz, el tallo, y las hojas, respectivamente. Concentraciones de 4 mg l-1, fueron letales para el cultivo; el fenómeno se apreció a partir de la etapa III de desarrollo, con la aparición de daños en las raíces y un fuerte efecto en la floración, que inhibió la formación de vainas.

  1. Peptide structural analysis using continuous Ar cluster and C60 ion beams. (United States)

    Aoyagi, Satoka; Fletcher, John S; Sheraz Rabbani, Sadia; Kawashima, Tomoko; Berrueta Razo, Irma; Henderson, Alex; Lockyer, Nicholas P; Vickerman, John C


    A novel application of time-of-flight secondary ion mass spectrometry (ToF-SIMS) with continuous Ar cluster beams to peptide analysis was investigated. In order to evaluate peptide structures, it is necessary to detect fragment ions related to multiple neighbouring amino acid residues. It is, however, difficult to detect these using conventional ToF-SIMS primary ion beams such as Bi cluster beams. Recently, C60 and Ar cluster ion beams have been introduced to ToF-SIMS as primary ion beams and are expected to generate larger secondary ions than conventional ones. In this study, two sets of model peptides have been studied: (des-Tyr)-Leu-enkephalin and (des-Tyr)-Met-enkephalin (molecular weights are approximately 400 Da), and [Asn(1) Val(5)]-angiotensin II and [Val(5)]-angiotensin I (molecular weights are approximately 1,000 Da) in order to evaluate the usefulness of the large cluster ion beams for peptide structural analysis. As a result, by using the Ar cluster beams, peptide molecular ions and large fragment ions, which are not easily detected using conventional ToF-SIMS primary ion beams such as Bi3 (+), are clearly detected. Since the large fragment ions indicating amino acid sequences of the peptides are detected by the large cluster beams, it is suggested that the Ar cluster and C60 ion beams are useful for peptide structural analysis.

  2. α1 -AR agonist induced piloerection protects against the development of traction alopecia. (United States)

    Goren, Andy; Shapiro, Jerry; Sinclair, Rodney; Kovacevic, Maja; McCoy, John


    Traction alopecia is hair loss that occurs after persistent pulling (e.g., during cosmetic procedures) on the roots of hair over time. Unlike plucking, which is painful, persistent pulling may go unnoticed until a patient presents with either bald spots or diffuse telogen shedding. Each hair follicle in the scalp contains an arrector pili muscle that, when contracted, erects the hair. The smooth muscle in the arrector pili expresses α1 adrenergic receptors (α1 -AR). As such, we hypothesized that contraction of the arrector pili muscle via an α1 -AR agonist would increase the threshold of force required to pluck hair during cosmetic procedures. Female subjects, ages 18-40, were recruited to study the effect of topically applied phenylephrine, a selective α1 -AR agonist, on epilation force and hair shedding during cosmetic procedures. In our blinded study, 80% of subjects demonstrated reduced shedding on days using phenylephrine compared to days using a placebo solution. The average reduction in hair loss was approximately 42%. In addition, the force threshold required for epilation increased by approximately 172% following topical phenylephrine application. To our knowledge this is the first study demonstrating the utility of α1 -AR agonists in the treatment of traction alopecia and hair shedding during cosmetic procedures. © 2015 Wiley Periodicals, Inc.

  3. The scattering of Ar from Ag(111): A molecular dynamics study.

    NARCIS (Netherlands)

    Lahaye, R.J.W.E.; Kleyn, A.W.; Stolte, S.; Holloway, S.


    A static potential energy surface (PES) for ArAg(111), based upon the local density approximation, is tested in a molecular dynamics study. The PES is a pairwise additive potential and no potential parameters are optimized to fit experimental data. A large crystal with nearest neighbour interaction

  4. Optimization of Coding of AR Sources for Transmission Across Channels with Loss

    DEFF Research Database (Denmark)

    Arildsen, Thomas

    . Channel coding is usually applied in combination with source coding to ensure reliable transmission of the (source coded) information at the maximal rate across a channel given the properties of this channel. In this thesis, we consider the coding of auto-regressive (AR) sources which are sources that can...


    The current USDA ARS Tropical Agriculture Research Station’s cacao (Theobroma cacao) collection consists of 154 clonally propagated accessions. Each accession is represented by six individual trees grafted on Amelonado rootstocks and planted in a completely randomized block design with three blocks...

  6. Vibrational spectra of some sulfide minerals from alšar (United States)

    Trajkovska, Magdalena; Šoptrajanov, Bojan; Jovanovski, Gligor; Stafilov, Trajče


    The infrared spectra (recorded at room temperature and at the boiling temperature of liquid nitrogen) of three minerals (lorandite, orpiment and realgar) from the Alšar ore deposit are presented and briefly discussed. Also presented are the Raman spectra (room temperature only) of the investigated minerals.

  7. ArFus: A Galaxy Formation Recipe for the General User (United States)

    Roukema, Boudewijn F.

    The galaxy formation modelling method of Roukema et al. (1997, {RPQR97}) is being updated into a software package called ArFus {RNDBGM}. ArFus combines the full non-linear information of the collapse of dark matter haloes from (pure gravity) N-body simulations with the flexibility and the rapidity of analytical formulae which represent gas thermodynamics and star formation in so-called "semi-analytical" galaxy formation models {KWG93,ColeGF94}. ArFus is written primarily in Fortran 77 and should be easily compilable on any Unix machine. The structure of the programme is modularised into subroutines for the different steps (detection of haloes, creation of halo merging tree, etc.). Documentation on the subroutines is automatically extracted directly from the compilable code and crosslinked in html format. A simple usage is to read in halo+galaxy merging trees prederived from N-body simulations for standard cosmological parameter values, and to output lists of galaxy absolute magnitudes and positions at desired output redshifts, based on input choices of star formation formulae. An example of more sophisticated usage would be to adopt the user's own N-body simulations and to derive halo merging history trees via ArFus. The simplest, black box, approach would be to use the output lists of galaxy absolute magnitudes and positions at desired output redshifts directly rather than recalculating these for chosen parameter options.

  8. Spectral line competition in a coaxial e-beam pumped high pressure Ar/Xe laser

    NARCIS (Netherlands)

    Lan, Y.F.; Lan, Y.F.; Peters, P.J.M.; Witteman, W.J.


    In order to study the kinetic mechanism of the e-beam pumped Ar/Xe laser, the temporal profiles of individual laser lines during multiline oscillation have been measured as a function of power deposition (1–12MW/cm3) and gas laser pressure (2–14 bar) using a short pulse (30 ns) coaxial electron beam

  9. Biological Effects of Low Energy Ar+ Ion Bombardment on Silkworm Eggs: a Novel Animal Model (United States)

    Xu, Jiaping; Wu, Yuejin; Liu, Xuelan; Yuan, Hang; Yu, Zengliang


    In this study, we found for the first time that silkworm eggs were able to survive in vacuum for a long period of time. Subsequently, low energy Ar+ ions with different energies and fluences were used to bombard silkworm eggs so as to explore the resulting biological effects. Results showed that (i) the exposure of silkworm eggs to vacuum within 10 min did not cause significant impact on the hatching rates, while the irradiation of silkworm eggs by Ar+ ions of 25 keV or 30 keV with fluences ranging from 2.6×2.6 × 1015 ion/cm2 to 8×2.6 × 1015 ion/cm2 caused a significant impact on the hatching rates, and the hatching rates decreased with the increase in the fluence and energy level; (ii) the irradiation of silkworm eggs by Ar+ ions of 30 keV with a fluence of 8×2.6 × 1015 ion/cm2 or 9×2.6 × 1015 ion/cm2 resulted in a noticeable etching on the egg shell surface which could be observed by a scanning electron microscope; and (iii) the irradiation of silkworm eggs by Ar+ ions of 30 keV with a fluence of 9×2.6 × 1015 ion/cm2 generated several mutant phenotypes which were observed in the 5th instar silkworms and a moth.

  10. 75 FR 32205 - Felsenthal National Wildlife Refuge, Ashley, Bradley, and Union Counties, AR; Overflow National... (United States)


    ... contracted labor. Land acquisitions within the approved acquisition boundary would be based on importance of... Fish and Wildlife Service Felsenthal National Wildlife Refuge, Ashley, Bradley, and Union Counties, AR... wildlife through the use of staff and contracted labor. Wildlife observation, wildlife photography, and...

  11. Fusarium mycotoxins: Current research at the USDA ARS Mycotoxin Prevention unit (United States)

    Due to the health and economic costs of mycotoxins produced by Fusarium species, there is a compelling need for improved understanding of these fungi, from across diverse perspectives and disciplinary approaches. Current research at the USDA ARS Mycotoxin Prevention unit addresses Fusarium mycotoxin...

  12. Electron emission yields from boron-like Ar ions impinging on Au(100)

    NARCIS (Netherlands)

    Bodewits, E.; Bekker, H.; de Nijs, A. J.; Hoekstra, R.; Winklehner, D.; Daniel, B.; Kowarik, G.; Dobes, K.; Aumayr, F.


    Using a new experimental station to be installed at the HITRAP facility at GSI we studied electron emission yields of Ar13+ ions impinging on a clean Au(1 00) surface. By taking data under different incidence angles and at different initial kinetic energies, contributions from kinetic and potential

  13. Sputtering yields of Ru, Mo, and Si under low energy Ar+ bombardment

    NARCIS (Netherlands)

    Wu, S. M.; van de Kruijs, R.; Zoethout, E.; F. Bijkerk,


    Ion sputtering yields for Ru, Mo, and Si under Ar+ ion bombardment in the near-threshold energy range have been studied using an in situ weight-loss method with a Kaufman ion source, Faraday cup, and quartz crystal microbalance. The results are compared to theoretical models. The accuracy of the in

  14. Sputtering yields of Ru, Mo and Si under low energy Ar+ bombardment

    NARCIS (Netherlands)

    Wu, Shiou-Min; van de Kruijs, Robbert Wilhelmus Elisabeth; Zoethout, E.; Zoethout, E.; Bijkerk, Frederik


    Ion sputtering yields for Ru, Mo, and Si under Ar+ ion bombardment in the near-threshold energy range have been studied using an in situ weight-loss method with a Kaufman ion source, Faraday cup, and quartz crystal microbalance. The results are compared to theoretical models. The accuracy of the in

  15. Sizeable beta-strength in 31Ar (beta 3p) decay

    DEFF Research Database (Denmark)

    T. Koldste, G.; Blank, B.; J. G. Borge, M.


    We present for the first time precise spectroscopic information on the recently discovered decay mode beta-delayed 3p-emission. The detection of the 3p events gives an increased sensitivity to the high energy part of the Gamow-Teller strength distribution from the decay of 31Ar revealing that as ...

  16. Transformation of the approach to breeding using genomics: Vison of USDA-ARS (United States)

    Traditional rice breeding methods have proven to be very successful with significant improvements in yield, grain quality, and resistances to biotic and abiotic stresses being seen in new cultivar releases every year. Research conducted by USDA ARS scientists at Stuttgart, Arkansas and Beaumont, Tex...

  17. Detecting single graphene layer by using fluorescence from high-speed Ar^7+ ion (United States)

    Miyamoto, Yoshiyuki; Zhang, Hong


    A highly-charged-ion interacting with graphite causes structural change in nano-scales [1]. While when the ion's kinetic energy reaches few MeVs, the induced is not the structural change but electronic excitation. An experiment [2] showed fluorescence from Ar^7+ ions penetrating through carbon foil with kinetic energy of 2 MeV. Motivated by this experiment, we tested interaction between an Ar^7+ ion and a graphene sheet by the time-dependent density functional approach, and found that the electronic excitation in the Ar^ 7+ ion is also the case even when the incident kinetic energy is 500 KeV and the target thickness is only mono-atomic layer. This simulation suggests the possibility of detecting a suspended mono-atomic layer of graphene [3] by monitoring fluorescence from the penetrated Ar^7+ ions. We will discuss its importance for analyzing bombardment of solids by highly charged, high-speed ions and possible experiments according to the present result. References: [1] T. Meguro, et al., Appl. Phys. Lett 79, 3866 (2001). [2] S. Bashkin, H. Oona, E. Veje, Phys, Rev. A25, 417 (1982). [3] J. Mayer et al., Nature (London), 446, 60 (2007).

  18. ARS Research on Harmful Algal Blooms in SE USA Aquaculture Impoundments (United States)

    As part of an EPA sponsored state of knowledge symposium on toxic cyanobacteria, six workgroups were established to assess published literature. A review of ARS research on harmful algal blooms was made by the incumbent. Aquaculture systems have had four types of freshwater toxic algal blooms. De...

  19. Decision Support System for Aquifer Recharge (AR) and Aquifer Storage and Recovery (ASR) Planning, Design, and Evaluation Decision Support System for Aquifer Recharge (AR) and Aquifer Storage and Recovery (ASR) Planning, Design, and Evaluation – Principles and Technical Basis (United States)

    Aquifer recharge (AR) is a technical method being utilized to enhance groundwater resources through man-made replenishment means, such as infiltration basins and injections wells. Aquifer storage and recovery (ASR) furthers the AR techniques by withdrawal of stored groundwater at...

  20. First dating of groundwater with Atom Trap Trace Analysis of 39Ar - application (United States)

    Reichel, Thomas; Kersting, Arne; Ritterbusch, Florian; Ebser, Sven; Bender, Klaus; Purtschert, Roland; Oberthaler, Markus; Aeschbach-Hertig, Werner


    Groundwater from the intermediate aquifer layers of the Rhine Graben sediments in the Rhein-Neckar metropolitan region is strongly exploited for the purpose of drinking water supply. Isotope hydrological investigations of the regional groundwater dynamics have been initiated with the ultimate goal of improving the protection of this important water resource. However, these studies are hampered by the fact that the groundwater falls in the age dating gap of classical isotope methods between about 50 and 1000 years of water age, which can only be bridged by the extremely rare isotope 39Ar. Here we report and discuss the first 39Ar groundwater ages obtained by the new analytical method Atom Trap Trace Analysis (ATTA). Groundwater samples from the Upper Rhine Graben aquifers were collected and analysed by established methods for a large range of tracers, including tritium, stable isotopes, noble gases, and 14C. For 39Ar analysis, several tons of water were degassed in the field using a membrane contactor. In the laboratory, a gas-chromatographic system at cryogenic temperatures was used to separate pure argon from the extracted gas. ATTA was then used to isolate and count 39Ar atoms from these samples. In parallel, samples for 39Ar analysis by low-level counting at the University of Bern were taken to enable comparison of the two analytical techniques. The resulting 39Ar groundwater ages in the range of several hundred years are in accordance with the indications obtained from the classical dating tracers. They provide quantitative information on the groundwater travel time for an important, strongly exploited part of the investigated aquifer system, which could not be obtained from the other tracers. These results significantly improve the knowledge of the time scale of groundwater renewal in the aquifer layers of intermediate depth. Furthermore, the combination of the 39Ar age scale with noble gas recharge temperatures and stable isotope data has the potential to

  1. Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis. (United States)

    Murahari, Sridhar; Jalkanen, Aimee L; Kulp, Samuel K; Chen, Ching-Shih; Modiano, Jaime F; London, Cheryl A; Kisseberth, William C


    Osteosarcoma (OS) is the most common primary bone tumor in both humans and dogs and is the second leading cause of cancer related deaths in children and young adults. Limb sparing surgery along with chemotherapy has been the mainstay of treatment for OS. Many patients are not cured with current therapies, presenting a real need for developing new treatments. Histone deacetylase (HDAC) inhibitors are a promising new class of anticancer agents. In this study, we investigated the activity of the novel HDAC inhibitor AR-42 in a panel of human and canine OS cell lines. The effect of AR-42 and suberoylanilide hydroxamic acid (SAHA) alone or in combination with doxorubicin on OS cell viability was assessed. Induction of histone acetylation after HDAC inhibitor treatment was confirmed by Western blotting. Drug-induced apoptosis was analyzed by FACS. Apoptosis was assessed further by measuring caspase 3/7 enzymatic activity, nucleosome fragmentation, and caspase cleavage. Effects on Akt signaling were demonstrated by assessing phosphorylation of Akt and downstream signaling molecules. AR-42 was a potent inhibitor of cell viability and induced a greater apoptotic response compared to SAHA when used at the same concentrations. Normal osteoblasts were much less sensitive. The combination of AR-42 with doxorubicin resulted in a potent inhibition of cell viability and apparent synergistic effect. Furthermore, we showed that AR-42 and SAHA induced cell death via the activation of the intrinsic mitochondrial pathway through activation of caspase 3/7. This potent apoptotic activity was associated with the greater ability of AR-42 to downregulate survival signaling through Akt. These results confirm that AR-42 is a potent inhibitor of HDAC activity and demonstrates its ability to significantly inhibit cell survival through its pleiotropic effects in both canine and human OS cells and suggests that spontaneous OS in pet dogs may be a useful large animal model for preclinical

  2. Subterranean production of neutrons, 39Ar and 21Ne: Rates and uncertainties (United States)

    Šrámek, Ondřej; Stevens, Lauren; McDonough, William F.; Mukhopadhyay, Sujoy; Peterson, R. J.


    Accurate understanding of the subsurface production rate of the radionuclide 39Ar is necessary for argon dating techniques and noble gas geochemistry of the shallow and the deep Earth, and is also of interest to the WIMP dark matter experimental particle physics community. Our new calculations of subsurface production of neutrons, 21Ne , and 39Ar take advantage of the state-of-the-art reliable tools of nuclear physics to obtain reaction cross sections and spectra (TALYS) and to evaluate neutron propagation in rock (MCNP6). We discuss our method and results in relation to previous studies and show the relative importance of various neutron, 21Ne , and 39Ar nucleogenic production channels. Uncertainty in nuclear reaction cross sections, which is the major contributor to overall calculation uncertainty, is estimated from variability in existing experimental and library data. Depending on selected rock composition, on the order of 107-1010 α particles are produced in one kilogram of rock per year (order of 1-103 kg-1 s-1); the number of produced neutrons is lower by ∼ 6 orders of magnitude, 21Ne production rate drops by an additional factor of 15-20, and another one order of magnitude or more is dropped in production of 39Ar. Our calculation yields a nucleogenic 21Ne /4He production ratio of (4.6 ± 0.6) ×10-8 in Continental Crust and (4.2 ± 0.5) ×10-8 in Oceanic Crust and Depleted Mantle. Calculated 39Ar production rates span a great range from 29 ± 9 atoms kg-rock-1 yr-1 in the K-Th-U-enriched Upper Continental Crust to (2.6 ± 0.8) × 10-4 atoms kg-rock-1 yr-1 in Depleted Upper Mantle. Nucleogenic 39Ar production exceeds the cosmogenic production below ∼700 m depth and thus, affects radiometric ages of groundwater. The 39Ar chronometer, which fills in a gap between 3H and 14C , is particularly important given the need to tap deep reservoirs of ancient drinking water.

  3. Timing and processes for exhumation of HP/LT rocks of the southern Brooks Range (AK): Insight from combined geochemistry and 40Ar/39Ar thermochronology of white mica (United States)

    O'Brien, T.; Miller, E. L.; Grove, M. J.; Hayden, L. A.


    The obduction of an island arc onto the Arctic Alaska continental margin in the Jura-Cretaceous led to southward subduction of continental crust and high-pressure/low-temperature (HP/LT) epidote-blueschist facies metamorphism in the southern Brooks Range (BR). A regionally developed greenschist facies normal-sense shear zone system along the southern margin of the BR suggests that extensional faulting had an influential role in the exhumation of the metamorphic core. To better constrain the exhumation history of the metamorphic core of the BR, samples were collected from a N-S transect through the metamorphic core of the orogen. Electron microprobe (EMP) analyses of white micas reveal that they are composed of phengite (Si > 3.0 pfu) or a combination of phengite + paragonite. Si-content of phengites reveal a southward increase in Si from 3.1 to 3.4 pfu (corresponding to an increase in pressure). Si-contents in higher-P phengites are scattered, reflecting subsequent muscovite growth. The Si trend is matched by a southward increase in the 40Ar/39Ar total gas ages of white micas. Phengite from the north are characterized by younger ages (~115 Ma) and flatter 40Ar/39Ar spectra. Farther south, phengites and paragonites yield older 40Ar/39Ar ages. These samples yield convex, staircase 40Ar/39Ar spectra that initiate ~115-120 Ma and flatten-out ~130-138 Ma. Modeling using MacArgon proposes that an initial cooling of HP/LT metamorphism occurred ~130-138 Ma, recorded in the high-Si phengites and paragonites. Following initial cooling, modeling suggests HP/LT rocks stalled in the greenschist facies field before subsequent exhumation, resulting in the staircase 40Ar/39Ar spectra. Flatter 40Ar/39Ar spectra recorded by the northern samples and modeling of 40Ar/39Ar results from the southern samples suggest that these rocks from metamorphic core of the BR were exhumed to temperatures < 300°C by ~115 Ma.

  4. Characterization, real-time quantification and in silico modeling of arsenate reductase (arsC) genes in arsenic-resistant Herbaspirillum sp. GW103. (United States)

    Govarthanan, Muthusamy; Lee, Sang-Myeong; Kamala-Kannan, Seralathan; Oh, Byung-Taek


    This study investigated the mechanism of arsenic resistance in the diazotrophic bacterium Herbaspirillum sp. GW103 isolated from rhizosphere soil of Phragmites austrails. The isolate Herbaspirillum sp. GW103 exhibited maximum tolerance to arsenic (550 mg/L). Four different arsenate reductase (arsC) genes (arsC1, arsC2, arsC3 and arsC4) were located in the genome of the isolate Herbaspirillum sp. GW103. The expression pattern of the arsC1 differed from other genes. All four types of arsC genes had different protein secondary structures and stereochemical properties. Molecular modeling and structural analysis of arsC genes revealed close structural homology with arsC family proteins from Escherichia coli (PDB ID: 1I9D) and Pseudomonas aeruginosa (PDB ID: 1RW1). Copyright © 2015 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  5. Oxygen functionalization of MWCNTs in RF-dielectric barrier discharge Ar/O2 plasma (United States)

    Abdel-Fattah, E.; Ogawa, D.; Nakamura, K.


    The oxygenation of multi-wall carbon nanotubes (MWCNTs) was performed via a radio frequency dielectric barrier discharge (RF-DBD) in an Ar/{{\\text{H}}2}\\text{O} plasma mixture. The relative intensity of the Ar/{{\\text{O}}2} plasma species was characterized by optical emission spectroscopy (OES). The effects of treatment time, RF power and oxygen gas percentage on the chemical composition and surface morphology of MWCNTs were investigated by means of x-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy and field emission scanning electron microscopy (FE-SEM). The results of FTIR and XPS revealed the presence of oxygen-containing functional groups on the MWCNTs treated in an Ar/{{\\text{O}}2} plasma at an RF power of 50 W and pressure of 400 Pa. The amount of oxygen functional groups (C=O, C-O, and O-COO) also increased by increasing treatment time up to 6 min, but slightly decreased when treatment time was increased by 10 min. The increase of oxygen gas percentage in the plasma mixture does not affect the oxygen content in the treated MWCNTs. Meanwhile, MWCNTs treated at high power (80 W) showed a reduction in oxygen functional groups in comparison with low RF power conditions. The Raman analysis was consistent with the XPS and FTIR results. The integrity of the nanotube patterns also remained damaged as observed by FE-SEM images. The MWCNTs treated in RF-DBD using the Ar/{{\\text{O}}2} plasma mixture showed improved dispersibility in deionized water. A correlation between the OES data and the observed surface characterization for an improved understanding of the functionalization of MWCNTs in Ar/{{\\text{O}}2} plasma was presented.

  6. Late consequences of ARS survivors of different {gamma}{beta}- and {gamma}{eta}-radiation injuries

    Energy Technology Data Exchange (ETDEWEB)

    Nadejina, N.M.; Galstian, I.A.; Savitsky, A.A.; Rtischeva, J.N.; Uvacheva, I.V. [State Research Center, Institute of Biophysics, Moscow (Russian Federation); Kashirina, O.G. [Clinical Hospital, Moscow (Russian Federation)


    Purpose: to study of health in the late consequences period the acute radiation syndrome (ARS) survivors of different radiation accidents took place in former USSR since 1953. Method: clinical observation, clinical database. Results: radiation cataract were revealed at the survivors who have undergone relatively uniform {gamma}{beta}-radiation exposure in a doze not less 2.0 Gy. At non-uniform {gamma}{eta}-radiation exposure the cataract development was observed at smaller dozes for bone marrow. The local radiation injures of skin were observed at relatively uniform {gamma}{beta}- and at non-uniform {gamma}{eta}-radiation exposure. The main factors for working disability are the presence of relapsing late radiation ulcers in the late period of local {gamma}{beta}-injures 2-4 degrees and the presence of amputation stumps at {gamma}{eta}-radiation exposure. For oncologic diseases developed in the period of late consequences of ARS the dose dependence is not revealed. Transient different changes of blood parameters are not dose dependent. The repeated (relatively stable) changes, as a rule, are connected to presence of heavy accompanying diseases (chronic hepatitis, myelodysplastic syndrome, family neutropenia). We observed development of chronic myeloleukemia at the ARS survivor. Hospital morbidity of these groups of ARS survivors demonstrates absence of the radiation influence to development of somatic pathology in the period of the late consequences. Conclusion: health of the ARS survivors in the late consequences period is determined by presence of consequences of local radiation injures of skin, radiation cataract and different concurrent somatic diseases. The type of irradiation ({gamma}{beta}- and {gamma}{eta}-) in many respects determines the speed of occurrence, expression and some clinical features of the late consequences of local radiation injures. (author)

  7. DC-SCRIPT: AR and VDR regulator lost upon transformation of prostate epithelial cells. (United States)

    Ansems, Marleen; Karthaus, Nina; Hontelez, Saartje; Aalders, Tilly; Looman, Maaike W; Verhaegh, Gerald W; Schalken, Jack A; Adema, Gosse J


    Nuclear receptors (NR), including the Androgen Receptor (AR) and the Vitamin D Receptor (VDR), play an important role in prostate cancer etiology. We recently found that DC-SCRIPT is a prognostic marker in breast cancer and a unique NR coregulator differentially regulating different classes of NRs. Here we investigated the importance of DC-SCRIPT in prostate cancer. DC-SCRIPT mRNA expression was measured by qPCR. Immunohistochemistry was used to detect DC-SCRIPT protein expression. The functional effects of DC-SCRIPT on the transcriptional activity of AR and VDR were assessed by luciferase reporter assays and qPCR assays on well-known AR and VDR target genes. DC-SCRIPT mRNA was higher in normal than in corresponding malignant prostate tissue but could not be related to disease stage. DC-SCRIPT protein was found in morphologically normal prostate glands and in infiltrating immune cells. Strikingly, DC-SCRIPT protein expression was absent in malignant prostate epithelial tissue and prostate carcinoma cell lines. DC-SCRIPT protein expression appears to be lost prior to the basal cell marker HMW cytokeratin used in prostate carcinoma diagnostics. In addition, our data demonstrated that DC-SCRIPT repressed transcription mediated by wild-type and mutated AR while enhancing VDR mediated transcription. In addition, transient expression of DC-SCRIPT expression in prostate carcinoma cells strongly repressed cell growth. DC-SCRIPT is a key regulator of nuclear receptors AR and VDR that play an opposite role in prostate cancer etiology and loss of DC-SCRIPT may be involved in the onset of prostate cancer. Copyright © 2012 Wiley Periodicals, Inc.

  8. Ibn Khaldūn’s Social Thought on Bedouin and Ḥaḍar

    Directory of Open Access Journals (Sweden)

    Moh. Pribadi


    [Melalui kerangka teori sosiologi modern serta metode penafsiran teks secara historis-sosiologis, penelitian ini berusaha untuk menjelaskan pemikiran sosial Ibn Khaldun tentang masyarakat badui dan ḥaḍar. Ide Ibnu Khaldun tentang masyarakat dapat dilihat pada konsepnya mengenai dua masyarakat ini beserta solidaritas sosial mereka, dengan karakteristik masing-masing. Masyarakat nomaden yang identik dengan masyarakat badui memiliki struktur sosial dan spesifisitas dengan kecenderungan pada kebajikan, ramah, dan keseragaman; sementara masyarakat ḥaḍar memiliki struktur dan kekhasan sosial seperti pluralis, pragmatis, dan hedonis. Dalam hal gaya hidup, masyarakat badui tampak lebih dinamis daripada ḥaḍar. Cara hidup masyarakat badui ditandai dengan terus berpindah dari satu tempat ke tempat lain, dan ini membuat komunitas ini cerdas dalam merumuskan visi, misi, program, dan sasaran yang ingin dicapai dalam hidup. Spesifisitas badui tercermin dalam kesiap-siagaan mereka, satu hal yang tidak terlihat dalam komunitas ḥaḍar. Sementara itu, dengan kemakmuranya, orang ḥaḍar sibuk dengan aktivitas perkotaan dan pembangunan masyarakat sipil. Ibn Khaldun telah berusaha untuk memahami manusia dan keberadaannya secara individu ataupun sosial melalui ‘ilm al-‘umrān. Metodologi sosialnya mencerminkan pandangannya secara keseluruhan melalui pengamatan realitas sosial secara komprehensif. Penulis berpendapat bahwa metodologi sosial Ibn Khaldun yang menggabungkan data dan fakta sosial dengan agama bisa menjadi referensi dan contoh pendekatan yang komprehensif. Ide penting Ibnu Khaldun lainnya adalah tentang perkembangan kecerdasan masyarakat yang meliputi tiga tahap: tamyīzī, tajrībī, dan naẓārī.

  9. 40Ar/(39Ar) geochronology of rhyolites erupted following collapse of the Yellowstone caldera, Yellowstone Plateau volcanic field: implications for crustal contamination (United States)

    Gansecki, C. A.; Mahood, G. A.; McWilliams, M. O.


    Single-crystal laser-probe 40Ar 39Ar dating of 133 grains of sanidine and plagioclase has enabled us to resolve the eruption ages of the Upper Basin Member rhyolites — the lava flows and related tuffs that erupted within the Yellowstone Caldera shortly after its collapse 630 ky ago on eruption of the Lava Creek Tuff. Two lavas and a tuff that erupted from the eastern ring-fracture zone yield an eruptive age of 481 ± 8 ka, whereas two flows from the western ring-fracture zone yield eruptive ages of 516 ± 7 and 198 ± 8 ka. Most of the units contain old xenocrysts, explaining why previous attempts at dating these earliest post-caldera units by the conventional K sbnd Ar method yielded poorly resolved and, in some cases, anomalous ages. The tuff shows the most severe contamination. Grains from a single pumice lapilli in the tuff show as large an age range as those from bulk vitrophyre, indicating that the xenocrysts were incorporated in the magma prior to its near-surface explosive fragmentation. Diffusion calculations indicate that the xenocrysts could not have remained in the magma for more than a few years without degassing and giving ages indistinguishable from the phenocrysts. Thus, the contamination represented by the xenocrysts probably occurred during fracturing and conduit propagation, rather than during caldera collapse, which took place more than 100 ky earlier. The apparent ages of xenocrysts and their compositions as determined by electron microprobe suggest that the Eocene Absaroka volcanics are the main contaminant, with a single xenocryst probably coming from Precambrian basement rocks. Most of the xenocrysts are difficult to distinguish optically or chemically from feldspar phenocrysts, illustrating the necessity of single-crystal to date many young volcanic rocks accurately.

  10. Comparison of U-Th and U-Pb zircon ages from erupted plutonic clasts and 40Ar/39Ar eruption ages from Newberry Volcano, Oregon (United States)

    Sullivan, K. M.; Stelten, M. E.; Leech, M. L.; Donnelly-Nolan, J. M.


    The magmatic plumbing systems of Quaternary volcanoes are poorly understood due to insufficient uplift and erosion to expose their intrusive roots. These intrusive bodies remained in the plumbing system for longer timescales than the eruptive melt; therefore, plutonic rocks record a more extensive history of the entire magmatic system. Occasionally, large-scale eruptions can expose regions of the plumbing system and/or erupt plutonic clasts (EPC) to the surface. We are investigating EPCs found within Newberry ash flow tuffs and hydrothermal drill cores to understand subsurface processes occurring within the magmatic plumbing system. Newberry Volcano is a large shield-shaped composite volcano located in central Oregon that has experienced recurrent volcanism from ca. 500 ka to 1,300 ybp. This study uses the EPC ages to link the intrusive rocks inferred to be representative of the Newberry magmatic plumbing system, and to discern a systematic relationship with volcanism. SHRIMP U-Th disequilibrium and U-Pb zircon ages were analyzed from six EPCs and two hydrothermal granitoids from separate drill cuttings. We compare these new SHRIMP ages to existing 40Ar/39Ar geochronology of Newberry volcanic strata. Three EPCs have unimodal zircon ages of 140 ka, two EPCs display ages of 300 ka, and one has three distinct zircon age populations of 120 ka, 200 ka, and 300 ka. Zircons from separate drill cuttings have ages of 350 ka and 1.9 Ma. All the EPC zircon ages are less than 500 kyr, implying that these clasts are related to the Newberry magmatic system. The granitoid with 1.9 Myr zircons was penetrated by drilling at 2.6 km depth, and could be related to Newberry magmatism and represent an earlier phase of intrusive activity. The 140 kyr zircons record a single crystallization event that took place during a period of frequent volcanism, while the three remaining age populations represent multiple periods of growth that overlap with timeframes of waning activity. Combining

  11. Paleomagnetism and 40ar/39ar Geochronology of the Plio-Pleistocene Boring Volcanic Field: Implications for the Geomagnetic Polarity Time Scale (United States)

    Hagstrum, J. T.; Fleck, R. J.; Evarts, R. C.; Calvert, A. T.; Conrey, R. M.


    The Boring volcanic field (BVF) in western Oregon and Washington has been the subject of a recently completed investigation that included detailed geologic mapping, petrographic and geochemical analyses, and 40Ar/39Ar geochronologic and paleomagnetic studies. At least 80 monogenetic volcanic centers compose the BVF, each of which erupted small volumes of magma ranging from basalt to mafic andesite over short intervals of time. More than 140 40Ar/39Ar determinations for lava flows and intrusions in the BVF range in age from ~3100 ka to ~60 ka. Oriented samples for paleomagnetic analysis were collected at an equivalent number of localities (>160) coincident with, or within the same unit proximal to, the geochronologic sampling sites. Based on the frequency distribution of ages, the most significant episodes of Boring volcanism occurred between 2700 and 2200 ka, 1700 and 500 ka, and 350 and 60 ka. A systematic determination of the BVF's eruptive history was undertaken mainly to assess its anomalous neotectonic setting west of the Cascade arc axis, as well as the magnitude of its concomitant volcanic hazards within the greater Portland and Vancouver metropolitan areas. Our paleomagnetic and geochronologic data, however, also have significant implications for the timing of geomagnetic field reversals and excursions during the Late Pliocene and Pleistocene epochs. The BVF data are more numerous higher in the section, and they capture transitional fields at two polarity boundaries allowing precise age determinations to be made for these reversals: the Brunhes-Matuyama transition is thus dated at 773±5 ka, and the upper Jaramillo-Matuyama transition at 973±6 ka. The lower Jaramillo-Matuyama transition occurred prior to 1068±8 ka, and the normal Cobb subchron must have occurred between reversed-polarity Matuyama flows dated at 1159±14 ka and 1207±6 ka. The lower Olduvai-Matuyama transition occurred prior to 1927±4 ka, and the Matuyama-Gauss transition prior to 2616

  12. Magnetostratigraphy and 39Ar/40Ar studies of the Lana'i Long Volcanic Sequence (ca. 1.606+/-0.063 Ma), Hawaii, USA (United States)

    Herrero-Bervera, E.; Jicha, B.; Valet, J.


    Previous published work on Lanai indicated that the volcano was formed mainly during the Matuyama Chron (Herrero-Bervera et al., 2000). In order to constrain further the timing of the active phases of the Lanai volcano, we conducted a paleomagnetic and rock magnetic study involving a ~500-m vertical thick sequence of lava flows that were erupted between 0.76+/-0.66 Ma and 1.6+/-0.09 Ma according to previous K/Ar and 40Ar/39Ar dating (Leonhardt et al., 2009). Low-field susceptibility versus temperature (k-T) and SIRM experiments performed on a dozen flows indicate that magnetite dominates the remanent magnetization (575°C). In a few cases, a low-temperature mineral phase (300-400°C) could reflect the presence of titanomagnetite with low Ti content, but the presence of maghemite or pyrrhotite cannot be completely excluded. Additional investigations are in progress on this matter. All specimens were step-wise demagnetized by alternating fields from 5 to 100 mT. Companion specimens from the same samples were demagnetized at 15 temperature steps. The demagnetization diagrams obtained with each technique showed a stable direction of remanence. In all cases, the characteristic (ChRM) component was clearly defined from at least seven successive directions isolated during step-wise demagnetization. The succession of the mean directions calculated for each lava flow reveals the existence of at least one polarity interval. Based on radiometric dates, they were assigned to the Gilsa, "excursion" (1.606+/-0.063 Ma). Thus, the present results, along with the radiometric ages of the lavas, indicate that the tholeiitic flows that formed the Lanai volcano were erupted over a short time period, and only during the Matuyama Chron (0.780-2.58 Ma). No eruptions have occurred during the Brunhes Chron (0.78 Ma) as previously indicated from K-Ar data on lavas in the Maunalei Gulch. The excursional VGPs from the onset of the Gilsa excursion recorded on Lanai are situated near the

  13. Age of the Lava Creek supereruption and magma chamber assembly at Yellowstone based on 40Ar/39Ar and U-Pb dating of sanidine and zircon crystals (United States)

    Vazquez, J. A.; Matthews, N. E.; Calvert, A. T.


    The last supereruption from the Yellowstone Plateau formed Yellowstone caldera and ejected the >1000 km3 of rhyolite that composes the Lava Creek Tuff (LCT). Tephra from the eruption blanketed much of the western United States, and is a key Quaternary chronostratigraphic marker, in particular for dating deposition of mid-Pleistocene glacial and pluvial deposits in western North America. We performed 40Ar/39Ar dating of single sanidines to delimit eruption age, and ion microprobe U-Pb and trace-element analyses of crystal faces on single zircons to characterize magmatic evolution and date near-eruption crystallization, as well as analyses of crystal interiors to date the interval of zircon crystallization. Sanidines from the two LCT members A and B yield an 40Ar/39Ar isochron date of 631 ± 4 ka (2σ). Crystal faces on zircons from both members yield a weighted mean 206Pb/238U date of 627 ± 6 ka (2σ) and have trace element concentrations that vary with eruptive stratigraphy. Zircon interiors yield a weighted mean 206Pb/238U date of 660 ± 6 ka, and reveal reverse and/or oscillatory zoning of trace element concentrations, with many crystals containing high-U concentrations and dark cathodoluminescence (CL) cores. These crystals with high-U cores are possibly sourced from 'defrosting' of melt-impregnated margins of the growing subvolcanic reservoir. LCT sanidines mirror the variation of zircon composition within the eruptive stratigraphy, with crystals from upper LCT-A and basal LCT-B having bright-CL rims with high Ba concentrations, suggesting late crystallization after addition of less evolved silicic magma. The occurrence of distal LCT in stratigraphic sequences marking the Marine Isotope Stage 16-15 transition supports the apparent eruption age of ca. 631 ka. These results reveal that Lava Creek zircons record episodic heating, renewed crystallization, and an overall up-temperature evolution for Yellowstone's subvolcanic reservoir in the 103-104 year interval

  14. Shortening of the European Dauphinois margin (Oisans Massif, Western Alps): New insights from RSCM maximum temperature estimates and 40Ar/39Ar in situ dating (United States)

    Bellanger, M.; Augier, R.; Bellahsen, N.; Jolivet, L.; Monié, P.; Baudin, T.; Beyssac, O.


    The Oisans Massif, located in the external zones of the western Alps, experienced significant shortening during the Alpine collision. While a series of major top-to-the west shear zones was recently described, the general low grade of the metamorphism has not attracted much petrological and geochronological studies. This paper provides combined temperature and age constraints on the evolution of the Oisans Massif. Temperature was estimated with the Raman Spectrometry of Carbonaceous Material (RSCM) method and chlorite geothermometry. Maximum temperature reached by the Mesozoic cover (Tmax) from Grenoble to the Galibier pass (E-W) and from Saint Jean de Maurienne to Embrun (N-S) yielded almost constant ca. 330 °C temperatures all through the Massif. Temperatures however strongly decrease either westward towards the top of the Vercors sedimentary sequence or eastward towards the Penninic Frontal Thrust. Age constraints were retrieved using 40Ar/39Ar in situ analyses performed on variously strained samples from Alpine shear zones. Over strain gradients, incipient Alpine recrystallizations progressively develop at the expense of former Variscan parageneses. A combined textural and EPMA approach permitted to identify newly formed chlorite and phengite that unequivocally grew in response to deformation or to low grade metamorphism. Chlorites recorded temperatures from ca. 350-150 °C during the activity of shear zones. In parallel, 40Ar/39Ar in situ experiments enabled dating deformation using both synkinematic phengites crystallized below the closure temperature of white-micas and former Variscan muscovite whose isotopic system have been, at least partially re-opened. Activity of top-to-the-west shear zones responsible for the shortening and thickening of the Oisans massif thus occurred between 34 and 33 and 25 Ma. Integrating these new age-constraints, Tmax estimates, and published geological data on the Oisans Massif and neighbouring areas allow proposing a new

  15. Timing of exhumation of the Ereendavaa metamorphic core complex (north-eastern Mongolia) - U-Pb and 40Ar/39Ar constraints (United States)

    Daoudene, Yannick; Ruffet, Gilles; Cocherie, Alain; Ledru, Patrick; Gapais, Denis


    The occurrence of numerous NE-SW trending rift basins that locally bound metamorphic core complexes in Transbaikalia, northern Mongolia and north-eastern China indicates that the eastern domain of the Central Asian Orogenic Belt was affected by a large-scale NW-SE extensional tectonic event during late Jurassic to early Cretaceous times. Available geochronological information about the formation of metamorphic core complexes in the region define partly synchronous periods in Transbaikalia (134-121 Ma) and North China (136-110 Ma) suggesting dome exhumation during the early Cretaceous. In north-eastern Mongolia, the Ereendavaa Range, lined by the Onon Shear Zone, was recently interpreted as one of these metamorphic core complexes, of late Jurassic to early Cretaceous age, on the basis of U-Pb zircons data from two synkinematic pegmatite dykes. However, this wide time range remains to be discussed. The present work constrains the tectono-thermal evolution of the range by providing new MC-ICP-MS U-Pb zircons ages from pegmatite dykes and metamorphic igneous rocks, and mica and amphibole 40Ar/39Ar laser step-heating ages from metamorphic and magmatic rocks that crop out within the range. The results show that (1) the Ereendavaa range was the locus of a widespread magmatic activity prior to its exhumation from late Jurassic times, (2) cooling of the range began at least at 137.9 ± 0.3 Ma as revealed by a 40Ar/39Ar plateau ages obtained from an hornblende sampled within the range core, and (3) exhumation along the Onon Shear Zone occurred from 130.3 ± 1.9 Ma down to 124.8 ± 0.3 Ma, as shown by ages of most of micas and amphiboles from the Shear zone. These more accurate ages are consistent with metamorphic core complex ages from adjacent areas. Furthermore, they argue for an extensional dynamic paroxysm at the scale of eastern Asia during a narrow time range in the early Cretaceous between ca. 130 Ma and ca. 120 Ma.

  16. Androgenic activity in surface water samples detected using the AR-LUX assay: Indications for mixture effects

    NARCIS (Netherlands)

    Blankvoort, B.M.G.; Rodenburg, R.J.T.; Murk, A.J.; Koeman, J.H.; Schilt, R.; Aarts, J.M.M.J.G.


    This paper describes the screening of 22 extracts from 18 different aquatic environmental samples for androgenic activity, including indirect and interactive effects on androgen receptor (AR)-mediated signal transduction, using the AR-LUX bioassay. Four samples, originating from an industrial

  17. Deep reactive ion etching of commercial PMMA in O2/CHF3, and O2/Ar-based discharges (United States)

    Zhang, Congchun; Yang, Chunsheng; Ding, Duifu


    The reactive ion etching of PMMA in O2, O2/CHF3 and O2/Ar discharges has been examined as a function of bias voltage, flow rate and composition of the gas mixtures. Etching in O2, O2/CHF3 and O2/Ar plasmas (with a flow ratio of Ar/O2 leq 50%) shows higher ion-enhanced chemical etching dependence than in O2/Ar (with a flow ratio of Ar/O2 geq 50%). In Ar/O2 plasmas, with an increasing proportion of Ar, the dominant process changed from an ion-enhanced chemical process with high values of etch rate to a physical sputtering etch process. PMMA etched in O2 (10 sccm)/Ar (40 sccm) produced a smooth and vertical sidewall. With an increasing amount of CHF3, the etch rates of PMMA show a larger dependence on physical sputtering and a gradual decrease. When the depth of PMMA etched in O2 (25 sccm)/CHF3 (25 sccm) is about 100 µm the profile is vertical, but the sidewall surface is rough.

  18. Ars Moriendi Tradition and Visualization of Death in Roman Baroque Sculpture: Death Education in the Seventeenth Century. (United States)

    Westin, Robert H.


    The tradition of the Ars Moriendi influenced art by creating a new reality in which the dead could appear eternally alive. A good death was seen as an act of faith. The literature of Ars Moriendi influenced baroque sculpture which today is viewed as almost bizarre. (JAC)

  19. K-Ar ages of low-grade metapelites from the Ryoke belt, the Iwakuni district, Yamaguchi Prefecture, Japan

    National Research Council Canada - National Science Library

    Owada, Masaaki; Midorikawa, Takahiro; Imaoka, Teruyoshi


    .... In this paper, we report on a method of sample preparation for, and results of, K-Ar dating. Samples obtained from a slate and a pelitic schist were collected for K-Ar dating from the low-grade parts of the Ryoke belt...

  20. Studies of $\\beta$-delayed two-proton emission : The cases of $^{31}$Ar and $^{35}$Ca

    CERN Multimedia

    Riisager, K; Jokinen, A; Canchel, G; Heinz, A M; Jonson, B N G; Dominguez reyes, R R; Koldste, G T; Fraile prieto, L M; Nilsson, T; Audirac, L L


    We propose to perform detailed studies of the decays of the two dripline nuclei $^{31}$Ar and $^{35}$Ca. This will allow an in-depth study in the process of $\\beta$-delayed two-proton emission ($\\beta$2p); as well as provide important information on resonances in $^{30}$S and $^{34}$Ar relevant for the astrophysical rp-process.

  1. Prioritization of Malus accessions for collection cryopreservation at the USDA-ARS National Center for Genetic Resources Preservation (United States)

    The USDA-ARS National Plant Germplasm System maintains a grafted collection of apple accessions representing 49 taxa in Geneva, NY. Dormant buds of many of these accessions have been routinely cryopreserved at the USDA-ARS National Center for Genetic Resources Preservation (NCGRP) in Fort Collins, C...

  2. Stilbene induced inhibition of androgen receptor dimerization: implications for AR and ARΔLBD-signalling in human prostate cancer cells.

    Directory of Open Access Journals (Sweden)

    Wolfgang Streicher

    Full Text Available BACKGROUND: Advanced castration resistant prostate cancer (CRPC is often characterized by an increase of C-terminally truncated, constitutively active androgen receptor (AR variants. Due to the absence of a ligand binding domain located in the AR-C-terminus, these receptor variants (also termed ARΔLBD are unable to respond to all classical forms of endocrine treatments like surgical/chemical castration and/or application of anti-androgens. METHODOLOGY: In this study we tested the effects of the naturally occurring stilbene resveratrol (RSV and (E-4-(2, 6-Difluorostyryl-N, N-dimethylaniline, a fluorinated dialkylaminostilbene (FIDAS on AR- and ARΔLBD in prostate cancer cells. The ability of the compounds to modulate transcriptional activity of AR and the ARΔLBD-variant Q640X was shown by reporter gene assays. Expression of endogenous AR and ARΔLBD mRNA and protein levels were determined by qRT-PCR and Western Blot. Nuclear translocation of AR-molecules was analyzed by fluorescence microscopy. AR and ARΔLBD/Q640X homo-/heterodimer formation was assessed by mammalian two hybrid assays. Biological activity of both compounds in vivo was demonstrated using a chick chorioallantoic membrane xenograft assay. RESULTS: The stilbenes RSV and FIDAS were able to significantly diminish AR and Q640X-signalling. Successful inhibition of the Q640X suggests that RSV and FIDAS are not interfering with the AR-ligand binding domain like all currently available anti-hormonal drugs. Repression of AR and Q640X-signalling by RSV and FIDAS in prostate cancer cells was caused by an inhibition of the AR and/or Q640X-dimerization. Although systemic bioavailability of both stilbenes is very low, both compounds were also able to downregulate tumor growth and AR-signalling in vivo. CONCLUSION: RSV and FIDAS are able to inhibit the dimerization of AR and ARΔLBD molecules suggesting that stilbenes might serve as lead compounds for a novel generation of AR-inhibitors.

  3. Screening β1AR inhibitors by cell membrane chromatography and offline UPLC/MS method for protecting myocardial ischemia. (United States)

    Yue, Yuan; Dou, Lili; Wang, Xin; Xue, Hui; Song, Yanhong; Li, Xiaoni


    A high expression β1AR/cell membrane chromatography (β1AR-CMC) and offline UPLC/MS method has been developed for screening active ingredients from Coptis chinensis. In this study, the fractions retained by CMC column were separated and identified by UPLC/MS system. Using metoprolol as a positive control drug, coptisine from C. chinensis was identified as the active component which could inhibit β1AR. Compared with the control group: coptisine could attenuate the infarct size and release malondialdehyde (MDA) while increasing superoxide dismutase (SOD) activity, suggesting a role in reducing myocardial injury. In vitro, coptisine could decrease apoptosis, showing their protective effects upon cardiomyocytes. This β1AR-CMC-offline-UPLC/MS method can be applied for screening active components acting on β1AR from traditional Chinese medicines. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

    Directory of Open Access Journals (Sweden)

    Gallagher William M


    Full Text Available Abstract Background Our group previously reported that tumour-specific expression of the rate-limiting enzyme in the mevalonate pathway, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR is associated with more favourable tumour parameters and a good prognosis in breast cancer. In the present study, the prognostic value of HMG-CoAR expression was examined in tumours from a cohort of patients with primary epithelial ovarian cancer. Methods HMG-CoAR expression was assessed using immunohistochemistry (IHC on tissue microarrays (TMA consisting of 76 ovarian cancer cases, analysed using automated algorithms to develop a quantitative scoring model. Kaplan Meier analysis and Cox proportional hazards modelling were used to estimate the risk of recurrence free survival (RFS. Results Seventy-two tumours were suitable for analysis. Cytoplasmic HMG-CoAR expression was present in 65% (n = 46 of tumours. No relationship was seen between HMG-CoAR and age, histological subtype, grade, disease stage, estrogen receptor or Ki-67 status. Patients with tumours expressing HMG-CoAR had a significantly prolonged RFS (p = 0.012. Multivariate Cox regression analysis revealed that HMG-CoAR expression was an independent predictor of improved RFS (RR = 0.49, 95% CI (0.25-0.93; p = 0.03 when adjusted for established prognostic factors such as residual disease, tumour stage and grade. Conclusion HMG-CoAR expression is an independent predictor of prolonged RFS in primary ovarian cancer. As HMG-CoAR inhibitors, also known as statins, have demonstrated anti-neoplastic effects in vitro, further studies are required to evaluate HMG-CoAR expression as a surrogate marker of response to statin treatment, especially in conjunction with current chemotherapeutic regimens.

  5. Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.

    LENUS (Irish Health Repository)

    Brennan, Donal J


    BACKGROUND: Our group previously reported that tumour-specific expression of the rate-limiting enzyme in the mevalonate pathway, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) is associated with more favourable tumour parameters and a good prognosis in breast cancer. In the present study, the prognostic value of HMG-CoAR expression was examined in tumours from a cohort of patients with primary epithelial ovarian cancer. METHODS: HMG-CoAR expression was assessed using immunohistochemistry (IHC) on tissue microarrays (TMA) consisting of 76 ovarian cancer cases, analysed using automated algorithms to develop a quantitative scoring model. Kaplan Meier analysis and Cox proportional hazards modelling were used to estimate the risk of recurrence free survival (RFS). RESULTS: Seventy-two tumours were suitable for analysis. Cytoplasmic HMG-CoAR expression was present in 65% (n = 46) of tumours. No relationship was seen between HMG-CoAR and age, histological subtype, grade, disease stage, estrogen receptor or Ki-67 status. Patients with tumours expressing HMG-CoAR had a significantly prolonged RFS (p = 0.012). Multivariate Cox regression analysis revealed that HMG-CoAR expression was an independent predictor of improved RFS (RR = 0.49, 95% CI (0.25-0.93); p = 0.03) when adjusted for established prognostic factors such as residual disease, tumour stage and grade. CONCLUSION: HMG-CoAR expression is an independent predictor of prolonged RFS in primary ovarian cancer. As HMG-CoAR inhibitors, also known as statins, have demonstrated anti-neoplastic effects in vitro, further studies are required to evaluate HMG-CoAR expression as a surrogate marker of response to statin treatment, especially in conjunction with current chemotherapeutic regimens.

  6. Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

    LENUS (Irish Health Repository)

    Brennan, Donal J


    Abstract Background Our group previously reported that tumour-specific expression of the rate-limiting enzyme in the mevalonate pathway, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) is associated with more favourable tumour parameters and a good prognosis in breast cancer. In the present study, the prognostic value of HMG-CoAR expression was examined in tumours from a cohort of patients with primary epithelial ovarian cancer. Methods HMG-CoAR expression was assessed using immunohistochemistry (IHC) on tissue microarrays (TMA) consisting of 76 ovarian cancer cases, analysed using automated algorithms to develop a quantitative scoring model. Kaplan Meier analysis and Cox proportional hazards modelling were used to estimate the risk of recurrence free survival (RFS). Results Seventy-two tumours were suitable for analysis. Cytoplasmic HMG-CoAR expression was present in 65% (n = 46) of tumours. No relationship was seen between HMG-CoAR and age, histological subtype, grade, disease stage, estrogen receptor or Ki-67 status. Patients with tumours expressing HMG-CoAR had a significantly prolonged RFS (p = 0.012). Multivariate Cox regression analysis revealed that HMG-CoAR expression was an independent predictor of improved RFS (RR = 0.49, 95% CI (0.25-0.93); p = 0.03) when adjusted for established prognostic factors such as residual disease, tumour stage and grade. Conclusion HMG-CoAR expression is an independent predictor of prolonged RFS in primary ovarian cancer. As HMG-CoAR inhibitors, also known as statins, have demonstrated anti-neoplastic effects in vitro, further studies are required to evaluate HMG-CoAR expression as a surrogate marker of response to statin treatment, especially in conjunction with current chemotherapeutic regimens.

  7. Apmierinātības ar attiecībām saistība ar pašcieņu.


    Bērziņa, Anda


    Pētījuma mērķis bija noskaidrot, kāda saistība pastāv romantiskās attiecībās iesaistītām sievietēm starp pašcieņu, no attiecībām atkarīgo pašcieņu un apmierinātību ar attiecībām. Kā arī pārbaudīt vai no attiecībām atkarīga pašcieņa kā konstrukts ir līdzīga pašcieņai. Pētījuma izlasi veidoja 50 sievietes vecumā no 20 līdz 30 gadiem, kuras atradās pastāvīgās romantiskās attiecībās vai bija precējušās 1 līdz 3 gadus. No visām respondentēm 7 bija precējušās, 28 bija neprecējušās, bet dzīvoja k...

  8. Stratigraphy and Ar/Ar geochronology of the Miocene lignite-bearing Tunçbilek-Domaniç Basin, western Anatolia (United States)

    Helvacı, C.; Ersoy, E. Y.; Billor, M. Z.


    The Tunçbilek-Domaniç Basin is one of the Neogene basins containing economic coal deposits in western Anatolia, Turkey. The basin fill represents fluvial to lacustrine sedimentary units which are interlayered with volcanic rocks with bimodal composition. In order to reveal the stratigraphy and the exact ages of the basin fill and coal deposits, and to explore the tectonic evolution of the basin, we present new field data and Ar/Ar age data from the volcanic units. The field studies and the age data indicate that the whole basin fills were deposited between 23 and 19 Ma (Aquitanian-Early Burdigalian) without any unconformity. Taking into account the ages of the coal-bearing sedimentary units in the other Neogene basins in the region, it is concluded that most of the economic coal deposits in the western Anatolia were formed during Aquitanian. The field studies also show that the deposition of the sedimentary units in the basin was controlled by the NE-SW-trending strike- to oblique-slip normal faults. In a regional scale, tectonic evolution of the Tunçbilek-Domaniç Basin is linked to the differential stretching in the hanging wall of the southerly located, a crustal-scale low-angle detachment fault (the Simav detachment fault) that controlled the Early Miocene exhumation of the Menderes Extensional Core Complex.

  9. Using 40Ar/39Ar ages of intercalated silicic tuffs to date flood basalts: Precise ages for Steens Basalt Member of the Columbia River Basalt Group (United States)

    Mahood, Gail A.; Benson, Thomas R.


    To establish causality between flood basalt eruptions and extinction events and global environmental effects recorded by isotopic excursions in marine sediments, highly accurate and precise ages for the flood basalts are required. But flood basalts are intrinsically difficult to date. We illustrate how 40Ar/39Ar feldspar ages for silicic tuffs intercalated with and overlying sections of Steens Basalt, the earliest lavas of the Middle Miocene Columbia River Basalt Group in the northwestern United States, provide high-precision ages that, for the first time, make it possible to resolve age differences with stratigraphic position within a section of these flood lavas. The stratigraphically lowest rhyolitic tuff, a fall deposit, yielded an age of 16.592 ± ± 0.028 Ma (FCs = 28.02 Ma), and the uppermost, the alkali rhyolite ignimbrite Tuff of Oregon Canyon, is 16.468 ± ± 0.014 Ma. The argon and stratigraphic data indicate that Steens Basalt eruptions occurred from ∼16.64 to 16.43 Ma in the southern end of its distribution. We estimate that the Steens Mountain geomagnetic reversal occurred at 16.496 ± ± 0.028 Ma (±0.18 Ma total error). Our estimates of the timing for initiation of volcanism and volumetric eruptive rates do not seem to support volcanic forcing by the initial stages of Columbia River Basalt Group eruptions as an explanation for the abrupt warming and carbonate dissolution at the beginning of the Miocene Climatic Optimum.

  10. Ar-Ar dating of K-feldspar in low grade metamorphic rocks: Example of an exhumed Mesozoic accretionary wedge and forearc, South Island, New Zealand (United States)

    Mortimer, N.; McLaren, S.; Dunlap, W. J.


    New 40Ar/39Ar ages from detrital K-feldspars and metamorphic white micas from the Eastern Province terranes of New Zealand have been used to investigate the thermo-tectonic history of different parts of an exhumed Mesozoic forearc basin and accretionary wedge. K-feldspars from barely metamorphosed sedimentary host rocks mainly record detrital source area ages whereas those from zeolite and prehnite-pumpellyite facies host rocks have textures and argon age spectra that indicate recrystallization during regional low-temperature metamorphism. The results contribute to a model that genetically links thermo-tectonic events across the accretionary wedge and forearc basin elements of the convergent margin, and into the Median Batholith arc probably by the Early Cretaceous and possibly by the Middle Jurassic. Thus, even though multidiffusion domain (MDD) models cannot be used to make inference on cooling histories in such situations, the K-feldspar argon thermochronometer can provide useful information on the timing of geological events in sub-greenschist facies rocks.

  11. A new high-precision 40Ar/39Ar age for the Rochechouart impact structure: At least 5 Ma older than the Triassic-Jurassic boundary (United States)

    Cohen, Benjamin E.; Mark, Darren F.; Lee, Martin R.; Simpson, Sarah L.


    The Rochechourt impact structure in south-central France, with maximum diameter of 40-50 km, has previously been dated to within 1% uncertainty of the Triassic-Jurassic boundary, at which time 30% of global genera became extinct. To evaluate the temporal relationship between the impact and the Triassic-Jurassic boundary at high precision, we have re-examined the structure's age using multicollector ARGUS-V 40Ar/39Ar mass spectrometry. Results from four aliquots of impact melt are highly reproducible, and yield an age of 206.92 ± 0.20/0.32 Ma (2σ, full analytical/external uncertainties). Thus, the Rochechouart impact structure predates the Triassic-Jurassic boundary by 5.6 ± 0.4 Ma and so is not temporally linked to the mass extinction. Rochechouart has formerly been proposed to be part of a multiple impact event, but when compared with new ages from the other purported "paired" structures, the results provide no evidence for synchronous impacts in the Late Triassic. The widespread Central Atlantic Magmatic Province flood basalts remain the most likely cause of the Triassic-Jurassic mass extinction.

  12. 40Ar/ 39Ar dating of the Jurassic volcanic province of Patagonia: migrating magmatism related to Gondwana break-up and subduction (United States)

    Féraud, G.; Alric, V.; Fornari, M.; Bertrand, H.; Haller, M.


    The Mesozoic large igneous province (LIP) of Patagonia (southern South America), which is one of the largest silicic provinces on Earth has been investigated by the 40Ar/ 39Ar method. Twenty-seven ages considered as valid, including twenty plateau ages, show that the volcanic activity, ranging from 187 to 144 Ma, occurred between and contemporaneously with the initial break-up of Gondwana (starting with the Karoo-Antarctic-Tasmanian (KAT) flood basalt province) in the east, and a subduction in the west. The data display a regular decreasing of ages from the ENE (187 Ma) to the WSW (144 Ma) along about 650 km, apparently related to the tectonic structure in half-grabens oriented NNW-SSE. The good fitting of this trend with the opening of the Rocas Verdes-Sarmiento marginal basin favors a space time evolution of this continental volcanism culminating towards the SSW in a continental disruption behind the magmatic arc. The observed age progression of volcanism may be the result of the variations of the physical characteristics of the subduction. The spreading and thermal effect of the KAT plume may have an additional effect and also could account for the unusually large volume of magma.

  13. Transpression and strain partitioning in the Caribbean Island-arc: Fabric development, kinematics and Ar Ar ages of syntectonic emplacement of the Loma de Cabrera batholith, Dominican Republic (United States)

    Escuder Viruete, J.; Contreras, F.; Stein, G.; Urien, P.; Joubert, M.; Ullrich, T.; Mortensen, J.; Pérez-Estaún, A.


    An integrative structural and geochronologic study of the Loma de Cabrera batholith (LCB, Cordillera Central, Dominican Republic) and its country rocks reveals the interplay of deformation, metamorphism and plutonism produced in the Caribbean island-arc during Late Cretaceous oblique convergence. The results emphasize the interference between three contemporaneous strain fields: (1) a northern and southern domains produced by (Meseta shear zone (LMSZ), active during the 88-74 Ma interval; and (3) the adjacent syn-kinematic emplacement of the LCB (90-74 Ma; 40Ar/ 39Ar in hornblende) during sinistral transpressional shearing. Comparison of the structural data with strain models of oblique plate convergence suggest that the LMSZ is a preserved ductile signature of strike-slip partitioning within a sinistral transpressional intra-oceanic subduction zone. In the LCB, microstructural data indicate that the magmatic to high-temperature solid-state deformation initially occurred over a wider band of heterogeneously distributed shear deformation, and was partitioned in narrow bands of mid- to low-temperature deformation connected with the LMSZ during the cooling of the batholith. Field and geochronologic studies also suggest that shortening across the southern domain took place concurrently with sinistral strike-slip movement along the crustal-scale La Guácara and Macutico fault zones, also consistent with a transpressional setting for the Late Cretaceous Caribbean magmatic arc. Shear and fault zones were variably reactivated during Upper Eocene-Oligocene thrusting and Miocene to Recent uplift of the Cordillera Central.

  14. 40Ar/39Ar dating of Quaternary lavas in northwest Iran: constraints on the landscape evolution and incision rates of the Turkish-Iranian plateau (United States)

    Allen, Mark B.; Mark, Darren F.; Kheirkhah, Monireh; Barfod, Dan; Emami, Mohammad H.; Saville, Christopher


    We report five new 40Ar/39Ar ages for basaltic lavas in the Maku region of northwest Iran, between ca. 1.87 and 0.40 Ma, which help constrain the tectonic and landscape evolution of this part of the Turkish-Iranian plateau. Flows originated from the composite volcanoes Ararat (Agri Dagi), Tendürek and Yigit Dagi, in eastern Turkey (Anatolia). These volcanoes are within the Turkish-Iranian plateau, which is a consequence of the Arabia-Eurasia collision, but has a poorly constrained evolution and surface uplift history. Current plateau elevations are typically 1.5-2 km, and relief between non-volcanic summits and basins is typically on the scale of ˜1 km. Samples are from flows that passed along pre-existing river valleys. Gorges were cut by re-established rivers after the eruptions, but the great majority of the local relief (˜95 per cent) lies above the sampled flows and so most likely pre-dates the volcanism. Gorge depths and lava ages allow local Quaternary fluvial incision rates to be calculated, which are ˜0.01 to 0.05 mm yr-1. These rates imply slow surface uplift of this part of the Turkish-Iranian plateau during the Quaternary. We therefore constrain the generation of the great majority of relief in the study area to be pre-Quaternary, and caused by the tectonic construction of the plateau, rather than a subcrustal origin related to the Quaternary magmatism.

  15. K/Ar geochronology as a tool for tracing dust provenance in the Southern Hemisphere (United States)

    Pu, J.; Koffman, B. G.; Recasens, C.; Hemming, S. R.; Kaplan, M. R.; Gombiner, J. H.; Boswell, S.; Williams, T.


    Determining the sources and transport pathways of dust can provide a better understanding of past atmospheric circulation and give insight into nutrient and radiative effects on the climate system. Mineralogy and radiogenic isotope chemistry using strontium (Sr) and neodymium (Nd) have been able to constrain sources of dust but are not sufficient to distinguish among important potential source areas in the Southern Hemisphere. The K/Ar isotope system can improve our ability to infer dust provenance because it can discriminate between sources that have similar crustal residence ages but different subsequent tectonothermal histories. To assess K/Ar ages as a provenance tool, we measured radiogenic argon concentrations of samples from potential dust sources such as glaciogenic sediments in Patagonia and New Zealand. Provenance ages from Patagonian sediments cluster around 70 Ma with a range from 33.2 ± 0.4 Ma to 120 ± 3 Ma, and those from New Zealand sediments cluster around 160 Ma with a range from 125 ± 1 Ma to 191 ± 2 Ma, showing that K/Ar geochronology can discriminate between these two source areas and improve upon previous provenance studies. In addition, as a proof of concept we made a case study of a sedimentary time series from core TN057-6 on the Agulhas Ridge in the southeast Atlantic Ocean as well as a set of Holocene and glacial samples from four cores along the SE African margin. We found that K/Ar provenance ages of the <5μm terrigenous material from TN057-6 are best explained as the result of mixing of sediments transported from Patagonia and Africa-derived sediments delivered by the Agulhas Current. The K/Ar method was also able to show different sediment provenance between glacial and interglacial times, with a dominant Patagonian signature during glacial intervals. Ongoing work aims to characterize additional Southern Hemisphere dust sources, including the ice-free regions of Antarctica, and apply the K/Ar provenance tool to dust in Antarctic

  16. HXeI and HXeH in Ar, Kr, and Xe matrices: experiment and simulation. (United States)

    Zhu, Cheng; Niimi, Keisuke; Taketsugu, Tetsuya; Tsuge, Masashi; Nakayama, Akira; Khriachtchev, Leonid


    Experimental and theoretical studies of HXeI and HXeH molecules in Ar, Kr, and Xe matrices are presented. HXeI exhibits the H-Xe stretching bands at 1238.0 and 1239.0 cm(-1) in Ar and Kr matrices, respectively, that are blue-shifted from the HXeI band observed in a Xe matrix (1193 cm(-1)) by 45 and 46 cm(-1). These shifts are larger than those observed previously for HXeCl (27 and 16 cm(-1)) and HXeBr (37 and 23 cm(-1)); thus, the matrix effect is stronger for less stable molecules. The results for HXeI are qualitatively different from all previous results on noble-gas hydrides with respect to the frequency order between Ar and Kr matrices. For previously studied HXeCl, HXeBr, and HXeCCH, the H-Xe stretching frequency is reliably (by >10 cm(-1)) higher in an Ar matrix than in a Kr matrix. In contrast, the H-Xe stretching frequency of HXeI in an Ar matrix is slightly lower than that in a Kr matrix. HXeH absorbs in Ar and Kr matrices at 1203.2 and 1192.1 cm(-1) (the stronger band for a Kr matrix), respectively. These bands are blue-shifted from the stronger band of HXeH in a Xe matrix (1166 cm(-1)) by 37 and 26 cm(-1), and this frequency order is the same as observed for HXeCl, HXeBr, and HXeCCH but different from HXeI. The present hybrid quantum-classical simulations successfully describe the main experimental findings. For HXeI in the 〈110〉 (double substitution) site, the order of the H-Xe stretching frequencies (ν(Xe) matrices from a Xe matrix are well predicted (30 and 34 cm(-1)). Both in the theory and experiment, the order of the H-Xe stretching frequencies differs from the case of HXeCl, which suggests the adequate theoretical description of the matrix effect. For HXeH in the 〈100〉 (single substitution) site, the order of the frequencies is ν(Xe) matrices with respect to a Xe matrix (36 and 23 cm(-1)) are in a good agreement with the experiments. The present calculations predict an increase of the H-Xe stretching frequencies in the noble-gas matrices

  17. C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid. (United States)

    Hornum, Lars; Hansen, Anker Jon; Tornehave, Ditte; Fjording, Marianne Scheel; Colmenero, Paula; Wätjen, Inger Falbe; Søe Nielsen, Niels Henrik; Bliddal, Henning; Bartels, Else Marie


    Complement activation correlates to rheumatoid arthritis disease activity, and increased amounts of the complement split product C5a is observed in synovial fluids from rheumatoid arthritis patients. Blockade of C5a or its receptor (C5aR) is efficacious in several arthritis models. The aim of this study was to investigate the role of C5a and C5aR in human rheumatoid arthritis and psoriatic arthritis-both with respect to expression and function. Synovial fluid, blood and synovial samples were obtained from rheumatoid arthritis, psoriatic arthritis and osteoarthritis patients as a less inflammatory arthritis type, and blood from healthy subjects. Cells infiltrating synovial tissue were analysed by immunohistochemistry and flow cytometry. SF and blood were analysed for biomarkers by flow cytometry or ELISA. The effect of a blocking anti-human C5aR mAb on leukocyte migration was determined using a Boyden chamber. Appropriate statistical tests were applied for comparisons. C5aR+ cells were detected in most rheumatoid arthritis, in all psoriatic arthritis, but not in non-inflammatory control synovia. C5aR+ cells were primarily neutrophils and macrophages. C5aR+ macrophages were mainly found in lymphoid aggregates in close contact with T cells. C5a levels were increased in both rheumatoid arthritis and psoriatic arthritis synovial fluid compared to osteoarthritis, and in blood from rheumatoid arthritis compared to healthy subjects. Neutrophil and monocyte migration to rheumatoid arthritis synovial fluid was significantly inhibited by anti-C5aR. The data support that the C5a-C5aR axis may be driving the infiltration of inflammatory cells into the synovial fluid and synovium in both rheumatoid and psoriatic arthritis, and suggest that C5a or C5aR may be a promising treatment target in both diseases.

  18. Ars Poetica. (United States)

    Stone, Tom


    Narrates the deterioration of a hyper-meticulous gardener in Austin, Texas, whose rage for order by day, and dionysian revels by night come into conflict when he must accept the botanical engineer of the month award at an evening banquet. Offers the story as an allegorical disclaimer of classical syllogistic reasoning. (JG)

  19. Acoustic rhinometry (AR): An Alternative Method to Image Nasal Airway Geometry

    DEFF Research Database (Denmark)

    Straszek, Sune; Pedersen, O.F.

    animals. Future prospects therefore could include development of new algorithms for computing data, more sensitive microphones measuring higher frequencies and optimal relationship between sound tube dimensions and the cavity measured. Achieving that may improve measurements, making pharmacological......  ACOUSTIC RHINOMETRY (AR): AN ALTERNATIVE METHOD TO IMAGE NASAL AIRWAY GEOMETRY.  INTRODUCTION AND BACKGROUND:  In human studies the acoustic reflection technique was first applied to describe the area-distance relationship of the lower airways, but later the acoustic reflection technique appeared...... Fourier transform. Based on the Ware and Aki algorithm measurements are displayed as an area-distance curve where cross-sectional area of the nasal cavity is a function of distance travelled by the sound wave.     DEMONSTRATION[OFP2] : Current problems using AR are demonstrated based on results from a few...

  20. Students and teachers as developers of visual designs with AR for visual arts education

    DEFF Research Database (Denmark)

    Buhl, Mie

    Students and teachers as developers of visual learning designs with AR for visual arts education. This paper reports from a project where communication students collaborated with art teacher educators and art student teachers about developing visual digital designs for learning which involved...... mobile technology and Augmented Reality (AR). The project exemplified a strategy for visual learning design where diverse stakeholders’ competences were involved throughout the design process. Visual arts education in Denmark is challenged by the national curricula’s requirement of integrating digital...... to question the purpose of using digital imaging and thereby lose the material experience from painting and drawing with tactile materials. The project’s pedagogical rationale behind integrating digital technologies in arts was that it should rather elicit different new art forms drawing on interactivity...

  1. A Study on Markerless AR-Based Infant Education System Using CBIR (United States)

    Lim, Ji-Hoon; Kim, Seoksoo

    Block play is widely known to be effective to help a child develop emotionally and physically based on learning by a sense of sight and touch. But block play can not expect to have learning effects through a sense of hearing. Therefore, in this study, such limitations are overcome by a method that recognizes an object made up of blocks, not a marker-based method generally used for an AR environment, a matching technology enabling an object to be perceived in every direction, and a technology combining images of the real world with 2D/3D images/pictures/sounds of a similar object. Also, an education system for children aged 3~5 is designed to implement markerless AR with the CBIR method.

  2. A volume averaged global model for inductively coupled HBr/Ar plasma discharge (United States)

    Chung, Sang-Young; Kwon, Deuk-Chul; Choi, Heechol; Song, Mi-Young


    A global model for inductively coupled HBr/Ar plasma was developed. The model was based on a self-consistent global model had been developed by Kwon et al., and a set of chemical reactions in the HBr/Ar plasma was compiled by surveying theoretical, experimental and evaluative researches. In this model vibrational excitations of bi-atomic molecules and electronic excitations of hydrogen atom were taken into account. Neutralizations by collisions between positive and negative ions were considered with Hakman's approximate formula achieved by fitting of theoretical result. For some reactions that were not supplied from literatures the reaction parameters of Cl2 and HCl were adopted as them Br2 and HBr, respectively. For validation calculation results using this model were compared with experimental results from literatures for various plasma discharge parameters and it showed overall good agreement.

  3. Improved morphed potentials for Ar-HBr including scaling to the experimentally determined dissociation energy. (United States)

    Wang, Z; McIntosh, A L; McElmurry, B A; Walton, J R; Lucchese, R R; Bevan, J W


    A lead salt diode infrared laser spectrometer has been employed to investigate the rotational predissociation in Ar-HBr for transitions up to J' = 79 in the v(1) HBr stretching vibration of the complex using a slit jet and static gas phase. Line-shape analysis and modeling of the predissociation lifetimes have been used to determine a ground-state dissociation energy D(0) of 130(1) cm(-1). In addition, potential energy surfaces based on ab initio calculations are scaled, shifted, and dilated to generate three-dimensional morphed potentials for Ar-HBr that reproduce the measured value of D(0) and that have predictive capabilities for spectroscopic data with nearly experimental uncertainty. Such calculations also provide a basis for making a comprehensive comparison of the different morphed potentials generated using the methodologies applied.

  4. Plasma chemistry in an atmospheric pressure Ar/NH3 dielectric barrier discharge

    DEFF Research Database (Denmark)

    Fateev, A.; Leipold, F.; Kusano, Y.


    absorption spectroscopy was also employed for the detection of stable products in the exhaust gas. To clarify the different processes for ammonia decomposition, N-2(2 - 10%) was added to the plasma. Modeling of the chemical kinetics in an Ar/NH3 plasma was performed as well. The dominant stable products...... of an atmospheric pressure Ar/NH3 DBD are H-2, N-2 and N2H4. The hydrazine (N2H4) concentration in the plasma and in the exhaust gases at various ammonia concentrations and different discharge powers was measured. Thermal N2H4 decomposition into NH2 radicals may be used for NOx reduction processes....

  5. TiArA: a virtual appliance for the analysis of Tiling Array data. (United States)

    Greenbaum, Jason A; Assarsson, Erika; Chung, Jo L; Head, Steven; Sette, Alessandro; Peters, Bjoern


    Genomic tiling arrays have been described in the scientific literature since 2003, yet there is a shortage of user-friendly applications available for their analysis. Tiling Array Analyzer (TiArA) is a software program that provides a user-friendly graphical interface for the background subtraction, normalization, and summarization of data acquired through the Affymetrix tiling array platform. The background signal is empirically measured using a group of nonspecific probes with varying levels of GC content and normalization is performed to enforce a common dynamic range. TiArA is implemented as a standalone program for Linux systems and is available as a cross-platform virtual machine that will run under most modern operating systems using virtualization software such as Sun VirtualBox or VMware. The software is available as a Debian package or a virtual appliance at

  6. Engaging Our School Teachers: an Augmented Reality (AR Approach to Continuous Professional Development

    Directory of Open Access Journals (Sweden)

    Debbie Holley


    Full Text Available Currently, teachers in the UK learn about behaviour management strategies from theoretical perspectives when training, through discussions with mentors, and by trial and error at their schools. Existing literature mainly focuses on such issues from the ‘adult’ viewpoint, not the voice of the child. This paper reports on work-in-progress developing a range of Augmented Reality (AR resources for these issues, drawing upon co-design research workshops with children from a Year 6 class (aged 10 in a UK Primary School. Our research informs approaches to classroom management by encouraging reflection and analysis of ‘critical incidents’ identified by the pupils, and explored by teachers in workshops through the medium of AR, giving a reality previously uncaptured in more traditional approaches. Our final resources will be a set of Open Education Resources (OER, offered to the wider community for reuse/repurposing for educational settings through a Creative Commons (cc licence.

  7. Comparison of PID and Fuzzy Controller for Position Control of AR.Drone (United States)

    Prayitno, A.; Indrawati, V.; Trusulaw, I. I.


    This paper describes the implementation of the PID Controller to control the position of the AR.Drone in the x-y-z. This position control scheme uses three PID controllers to maintain the position of x, y and z using the signal control pitch, roll and vertical rate. PID Controller implemented on AR.Drone 2.0 and then tested in an indoor space. The performance of the controller will be compared with Fuzzy Logic Controller schemes that have been implemented previously. The results show that the PID Controller generate a response with rise time less than 3 seconds at the x and y position with around 25% overshoot. The result for z position give better result without overshoot. The comparison between fuzzy logic and PID Controller indicates that the results of the PID controller is better although there is overshoot.

  8. TiArA: a virtual appliance for the analysis of Tiling Array data.

    Directory of Open Access Journals (Sweden)

    Jason A Greenbaum


    Full Text Available Genomic tiling arrays have been described in the scientific literature since 2003, yet there is a shortage of user-friendly applications available for their analysis.Tiling Array Analyzer (TiArA is a software program that provides a user-friendly graphical interface for the background subtraction, normalization, and summarization of data acquired through the Affymetrix tiling array platform. The background signal is empirically measured using a group of nonspecific probes with varying levels of GC content and normalization is performed to enforce a common dynamic range.TiArA is implemented as a standalone program for Linux systems and is available as a cross-platform virtual machine that will run under most modern operating systems using virtualization software such as Sun VirtualBox or VMware. The software is available as a Debian package or a virtual appliance at

  9. Design and Error Analysis of a Vehicular AR System with Auto-Harmonization. (United States)

    Foxlin, Eric; Calloway, Thomas; Zhang, Hongsheng


    This paper describes the design, development and testing of an AR system that was developed for aerospace and ground vehicles to meet stringent accuracy and robustness requirements. The system uses an optical see-through HMD, and thus requires extremely low latency, high tracking accuracy and precision alignment and calibration of all subsystems in order to avoid mis-registration and "swim". The paper focuses on the optical/inertial hybrid tracking system and describes novel solutions to the challenges with the optics, algorithms, synchronization, and alignment with the vehicle and HMD systems. Tracker accuracy is presented with simulation results to predict the registration accuracy. A car test is used to create a through-the-eyepiece video demonstrating well-registered augmentations of the road and nearby structures while driving. Finally, a detailed covariance analysis of AR registration error is derived.

  10. K-Ar age constrains on chemically weathered granitic basement rocks (saprolites) in Scandinavia (United States)

    Margreth, Annina; Fredin, Ola; Viola, Giulio; Knies, Jochen; Sørlie, Ronald; Lie, Jan-Erik; Margrethe Grandal, Else; Zwingmann, Horst; Vogt, Christoph


    Remnants of in-situ weathered bedrock, saprolite, are found in several locations in Scandinavia. Saprolites contain important information about past climate conditions and landscape evolution, although their age and genesis are commonly difficult to constrain. It is generally thought that clay-poor, coarse-grained (arêne) saprolites, mostly occurring as thin regolith blankets or in larger outcrops, formed in temperate climate during the Cenozoic, whereas clay-rich (argillic) saprolites, commonly restricted to small, fracture-bounded outcrops, formed in (sub-)tropical climate during the Mesozoic. Recent methodological and conceptual advances in K-Ar dating of illite-bearing fault rocks have been applied to date clay-rich saprolites. To test the K-Ar dating technique for saprolites, we first selected an offshore site in the Viking Graben of the North Sea, where weathered and fractured granitic basement highs have been drilled during petroleum exploration, and an abandoned kaolin mine in Southern Sweden. Both targets provide independent age control through the presence of overlying Mesozoic sedimentary rocks. Clay-rich saprolites occurring in fractured basement rocks were additionally sampled in a joint valley landscape on the southwestern coast of Norway, which can be regarded as the possible onland correlative to the offshore basement high. In order to offer a sound interpretation of the obtained K-Ar ages, the mineralogical and chemical composition of the saprolites requires a thorough characterization. Scanning electron microscopy of thin sections, integrated by XRD and XRF analysis, reveals the progressive transformation of primary granitic rock minerals into secondary clay minerals. The authigenesis of illite is particularly important to understand, since it is the only K-bearing clay mineral that can be dated by the K-Ar method. K-feldspars and mica are the common primary K-bearing minerals, from which illite can be formed. While progressive leaching of

  11. Detection of a noble gas molecular ion, 36ArH+, in the Crab Nebula. (United States)

    Barlow, M J; Swinyard, B M; Owen, P J; Cernicharo, J; Gomez, H L; Ivison, R J; Krause, O; Lim, T L; Matsuura, M; Miller, S; Olofsson, G; Polehampton, E T


    Noble gas molecules have not hitherto been detected in space. From spectra obtained with the Herschel Space Observatory, we report the detection of emission in the 617.5- and 1234.6-gigahertz J = 1-0 and 2-1 rotational lines of (36)ArH(+) at several positions in the Crab Nebula, a supernova remnant known to contain both molecular hydrogen and regions of enhanced ionized argon emission. Argon-36 is believed to have originated from explosive nucleosynthesis in massive stars during core-collapse supernova events. Its detection in the Crab Nebula, the product of such a supernova event, confirms this expectation. The likely excitation mechanism for the observed (36)ArH(+) emission lines is electron collisions in partially ionized regions with electron densities of a few hundred per centimeter cubed.

  12. Neutron scattering study of 36 Ar monolayer films adsorbed on graphite

    DEFF Research Database (Denmark)

    Taub, H.; da Costa Carneiro, Kim; Kjems, Jørgen


    Diffraction of neutrons from 36 Ar monolayers adsorbed on graphite basal planes indicates that an ordered, two-dimensional (2D) triangular lattice is formed at low temperature. The lattice constant is found to be slightly larger than that of the bulk 3D solid but significantly smaller than...... surfaces at low temperatures) are observed to decrease smoothly above 40 K, falling from 100 to 15 Å at 80 K. Little if any positional order remains at temperatures where the nearest-neighbor distance in the monolayer matches that of a registered √3×√3 phase. The spectrum of neutrons inelastically...... scattered from 36 Ar monolayers in the nominally in-plane configuration can be reasonably well described at low temperatures by a 2D harmonic-phonon model while the scattering in the out-of-plane configuration seems to be best represented in terms of a resonant coupling of the monolayer film to out...

  13. Vibrational spectrum of Ar3+ and relative importance of linear and perpendicular isomers in its photodissociation (United States)

    Karlický, František; Lepetit, Bruno; Kalus, René; Gadéa, Florent Xavier


    The photodissociation dynamics of the argon ionized trimer Ar_3^+ is revisited in the light of recent experimental results of Lepère et al. [J. Chem. Phys. 134, 194301 (2009)], which show that the fragment with little kinetic energy is always a neutral one, thus the available energy is shared by a neutral and ionic fragments as in Ar_2^+. We show that these results can be interpreted as the photodissociation of the linear isomer of the system. We perform a 3D quantum computation of the vibrational spectrum of the system and study the relative populations of the linear (trimer-core) and perpendicular (dimer-core) isomers. We then show that the charge initially located on the central atom in the ground electronic state of the linear isomer migrates toward the extreme ones in the photoexcitation process such that photodissociation of the linear isomer produces a neutral central atom at rest in agreement with measured product state distributions.

  14. Vibrational spectrum of Ar3(+) and relative importance of linear and perpendicular isomers in its photodissociation. (United States)

    Karlický, Frantisek; Lepetit, Bruno; Kalus, René; Gadéa, Florent Xavier


    The photodissociation dynamics of the argon ionized trimer Ar(3)(+) is revisited in the light of recent experimental results of Lepère et al. [J. Chem. Phys. 134, 194301 (2009)], which show that the fragment with little kinetic energy is always a neutral one, thus the available energy is shared by a neutral and ionic fragments as in Ar(2)(+). We show that these results can be interpreted as the photodissociation of the linear isomer of the system. We perform a 3D quantum computation of the vibrational spectrum of the system and study the relative populations of the linear (trimer-core) and perpendicular (dimer-core) isomers. We then show that the charge initially located on the central atom in the ground electronic state of the linear isomer migrates toward the extreme ones in the photoexcitation process such that photodissociation of the linear isomer produces a neutral central atom at rest in agreement with measured product state distributions.

  15. Energy Dependent Stereodynamics of the Ne (3P2)+Ar Reaction (United States)

    Gordon, Sean D. S.; Zou, Junwen; Tanteri, Silvia; Jankunas, Justin; Osterwalder, Andreas


    The stereodynamics of the Ne (P2 3 )+Ar Penning and associative ionization reactions have been studied using a crossed molecular beam apparatus. The experiment uses a curved magnetic hexapole to polarize the Ne (P2 3 ) , which is then oriented with a shaped magnetic field in the region where it intersects with a beam of Ar (S 1 ) . The ratios of Penning to associative ionization were recorded over a range of collision energies from 320 to 500 cm-1 and the data were used to obtain Ω state dependent reactivities for the two reaction channels. These reactivities were found to compare favorably to those predicted in the theoretical work of Brumer et al.

  16. Energy Dependent Stereodynamics of the Ne(^{3}P_{2})+Ar Reaction. (United States)

    Gordon, Sean D S; Zou, Junwen; Tanteri, Silvia; Jankunas, Justin; Osterwalder, Andreas


    The stereodynamics of the Ne(^{3}P_{2})+Ar Penning and associative ionization reactions have been studied using a crossed molecular beam apparatus. The experiment uses a curved magnetic hexapole to polarize the Ne(^{3}P_{2}), which is then oriented with a shaped magnetic field in the region where it intersects with a beam of Ar(^{1}S). The ratios of Penning to associative ionization were recorded over a range of collision energies from 320 to 500  cm^{-1} and the data were used to obtain Ω state dependent reactivities for the two reaction channels. These reactivities were found to compare favorably to those predicted in the theoretical work of Brumer et al.

  17. Imaging the inelastic scattering of vibrationally excited NO (v = 1) with Ar (United States)

    Kamasah, Alexander; Li, Hongwei; Onvlee, Jolijn; van der Avoird, Ad; Parker, David H.; Suits, Arthur G.


    The inelastic scattering of vibrationally excited NO (v = 1) with Ar at a collision energy of 3.0 kcal mol-1 was investigated in crossed beams. Vibrationally excited NO was generated by flash heating and rotationally cooled by the supersonic expansion. The differential cross sections were compared to those of the vibrational ground state NO (v = 0) with Ar, which were also compared to theoretical calculations for scattering from the ground vibrational level. The differential cross sections show a similar strong j dependence of the rotational rainbow maxima from the inelastic scattering for both NO (v = 0) and (v = 1) but no significant differences between NO (v = 0) and (v = 1) were seen.

  18. Correlation between photoeletron and photoion in ultrafast multichannel photoionization of Ar

    Energy Technology Data Exchange (ETDEWEB)

    Itakura, R. [Kansai Photon Science Institute, Japan Atomic Energy Agency, Kizugawa, Kyoto 619-0215 (Japan); Fushitani, M.; Hishikawa, A. [Nagoya University, Nagoya, Aichi 464-8602 (Japan); Sako, T. [Nihon University, Funabashi, Chiba 274-8501 (Japan)


    We theoretically investigate coherent dynamics of ions created through ultrafast multichannel photoionization from a viewpoint of photoelectron-photoion correlation. The model calculation on single-photon ionization of Ar reveals that the coherent hole dynamics in Ar{sup +} associated with a superposition of the spin-orbit states {sup 2}PJ (J = 3/2 and 1/2) can be identified by monitoring only the photoion created by a Fourier-transform limited extreme ultraviolet (EUV) pulse with the fs pulse duration, while the coherence is lost by a chirped EUV pulse. It is demonstrated that by coincidence detection of the photoelectron and photoion the coherent hole dynamics can be extracted even in the case of ionization by a chirped EUV pulse with the sufficiently wide bandwidth.

  19. ARS 06 Helsingis Kiasmas näitab heitlikku ja surelikku inimest / Ave Randviir

    Index Scriptorium Estoniae

    Randviir, Ave, 1981-


    Helsingi kaasaegse kunsti muuseumi Kiasma ARS 06 ekspositsioonist. Zhanriliselt mitmekesine näitus 24 maa kunstnike töödest näib sumbuvat täielikku morbiidsusse. Alates märtsist on näitusel väljas ainsa eesti osaleja Mark Raidpere video "10 meest". Lisaks intervjuu "Metsas juhtub jubedaid asju" Walter Martini ja Paloma Munoz'iga ning "Inimestele meeldib vägivald" Kent Henrickseniga



    Muhammad Nanda Kurniawan; Didit Widiyanto


    Abstract In this research, Parrot AR.Drone as an Unmanned Aerial Vehicle (UAV) was used to track an object from above. Development of this system utilized some functions from OpenCV library and Robot Operating System (ROS). Techniques that were implemented in the system are image processing al-gorithm (Centroid-Contour Distance (CCD)), feature extraction algorithm (Principal Component Analysis (PCA)) and an artificial neural network algorithm (Generalized Learning Vector Quantization (GLV...