The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti
Pini, Francesco; Frage, Benjamin; Ferri, Lorenzo; De Nisco, Nicole J.; Mohapatra, Saswat S.; Taddei, Lucilla; Fioravanti, Antonella; Dewitte, Frederique; Galardini, Marco; Brilli, Matteo; Villeret, Vincent; Bazzicalupo, Marco; Mengoni, Alessio; Walker, Graham C.; Becker, Anke; Biondi, Emanuele G.
2013-01-01
SUMMARY Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with higher membrane permeability. In Caulobacter crescentus, a related alphaproteobacterium, the principal cell cycle regulator, CtrA, is inhibited by the phosphorylated response regulator DivK. The phosphorylation of DivK depends on the histidine kinase DivJ, while PleC is the principal phosphatase for DivK. Despite the importance of the DivJ in C. crescentus, the mechanistic role of this kinase has never been elucidated in other Alphaproteobacteria. We show here that the histidine kinases DivJ together with CbrA and PleC participate in a complex phosphorylation system of the essential response regulator DivK in S. meliloti. In particular, DivJ and CbrA are involved in DivK phosphorylation and in turn CtrA inactivation, thereby controlling correct cell cycle progression and the integrity of the cell envelope. In contrast, the essential PleC presumably acts as a phosphatase of DivK. Interestingly, we found that a DivJ mutant is able to elicit nodules and enter plant cells, but fails to establish an effective symbiosis suggesting that proper envelope and/or low CtrA levels are required for symbiosis. PMID:23909720
International Nuclear Information System (INIS)
Ahmed, A.; Sabri, A.N.
2004-01-01
In B.subtilis, cell division is controlled by div-genes which have been mapped on its circular chromosome. In the present work, div-mutant strains 1A316(div II), 1A317 and 1A318 (div I) were studied. These strains exhibited temperature sensitive cell division mutations. Colony morphology, cell morphology, staining behavior, growth rate and protein content of PY79 (wild type) and div-mutant strains (1A316, 1A317, 1A318) was studied at different temperatures ( 25 deg. Centi grade and 42 deg. with varying incubation periods(4, 16, 24, 48, 72,96 hrs). div-mutants differ from wild type (PY79) in colony morphology. Colony margin in PY79 was entire while in the div strains it is undulate. Staining behavior of cells as well as cell morphology i.e., cell size, cell types, formation of filaments/minicells were affected by high temperature. At higher temperature (42 deg. Centi grade), div-mutants undergo more severe lysis and degeneration as compare to wild type (PY79). Defective spores were produced by div-mutants at 25 deg. Centi grade and 42 deg. Centi grade. Tetrazolium overlay test was performed at 37 deg. Centi grade and 42 deg. Centi grade to check the spore germination ability of wild type and div-mutants. In 1A318, defective spores were produced at 37 deg. Centi grade, div-mutant was checked after 24 and 96 hrs at different temperatures (25, 37 and 42 deg. Centi grade). At all temperatures protein content were more in PY79 as compare to div-mutants. Also at 25 and 42 deg. Centi grade, protein content was more as compare to 37 deg. Centi grade. Protein contents was reduced at sporulation stages. Thus cell division mutations affect cell morphology, sporulation and germination processes in B.subtilis and thus are multifaceted mutations. (author)
Phyto-gegographycal analysis of Divčibare
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Popović Ivana
2005-01-01
Full Text Available The aim of phytogeographical analysis is to determine the plant species origin, genesis and migrations. The study results contribute to the knowledge of phytogeographical classification of the particular regions. Different chorions, by their effects, determine the flora structure and composition. The aim of the floristic research of Divčibare was to identify the diversity of flora in this region, i.e., in a wider sense, the diversity of flora in Serbia. Phytogeographical analysis was based on floristic research. The identified plant species were classified into the corresponding floral elements, area groups and area types. The data on diversity and the degree of representation in the flora of Divčibare were obtained based on the percentage of each area type. It was concluded that the flora of Divčibare has a transitional, Central European-Mediterranean-Pontic character.
Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains.
Hsu, Eric J; Zhu, Wandi; Schubert, Angela R; Voelker, Taylor; Varga, Zoltan; Silva, Jonathan R
2017-03-06
Functional eukaryotic voltage-gated Na + (Na V ) channels comprise four domains (DI-DIV), each containing six membrane-spanning segments (S1-S6). Voltage sensing is accomplished by the first four membrane-spanning segments (S1-S4), which together form a voltage-sensing domain (VSD). A critical Na V channel gating process, inactivation, has previously been linked to activation of the VSDs in DIII and DIV. Here, we probe this interaction by using voltage-clamp fluorometry to observe VSD kinetics in the presence of mutations at locations that have been shown to impair Na V channel inactivation. These locations include the DIII-DIV linker, the DIII S4-S5 linker, and the DIV S4-S5 linker. Our results show that, within the 10-ms timeframe of fast inactivation, the DIV-VSD is the primary regulator of inactivation. However, after longer 100-ms pulses, the DIII-DIV linker slows DIII-VSD deactivation, and the rate of DIII deactivation correlates strongly with the rate of recovery from inactivation. Our results imply that, over the course of an action potential, DIV-VSDs regulate the onset of fast inactivation while DIII-VSDs determine its recovery. © 2017 Hsu et al.
SecA is required for membrane targeting of the cell division protein DivIVA in vivo
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Sven eHalbedel
2014-02-01
Full Text Available The conserved protein DivIVA is involved in different morphogenetic processes in Gram-positive bacteria. In Bacillus subtilis, the protein localises to the cell division site and cell poles, and functions as a scaffold for proteins that regulate division site selection, and for proteins that are required for sporulation. To identify other proteins that bind to DivIVA, we performed an in vivo cross-linking experiment. A possible candidate that emerged was the secretion motor ATPase SecA. SecA mutants have been described that inhibit sporulation, and since DivIVA is necessary for sporulation, we examined the localisation of DivIVA in these mutants. Surprisingly, DivIVA was delocalised, suggesting that SecA is required for DivIVA targeting. To further corroborate this, we performed SecA depletion and inhibition experiments, which provided further indications that DivIVA localisation depends on SecA. Cell fractionation experiments showed that SecA is important for binding of DivIVA to the cell membrane. This was unexpected since DivIVA does not contain a signal sequence, and is able to bind to artificial lipid membranes in vitro without support of other proteins. SecA is required for protein secretion and membrane insertion, and therefore its role in DivIVA localisation is likely indirect. Possible alternative roles of SecA in DivIVA folding and/or targeting are discussed.
Parallel Auxiliary Space AMG Solver for $H(div)$ Problems
Energy Technology Data Exchange (ETDEWEB)
Kolev, Tzanio V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2012-12-18
We present a family of scalable preconditioners for matrices arising in the discretization of $H(div)$ problems using the lowest order Raviart--Thomas finite elements. Our approach belongs to the class of “auxiliary space''--based methods and requires only the finite element stiffness matrix plus some minimal additional discretization information about the topology and orientation of mesh entities. Also, we provide a detailed algebraic description of the theory, parallel implementation, and different variants of this parallel auxiliary space divergence solver (ADS) and discuss its relations to the Hiptmair--Xu (HX) auxiliary space decomposition of $H(div)$ [SIAM J. Numer. Anal., 45 (2007), pp. 2483--2509] and to the auxiliary space Maxwell solver AMS [J. Comput. Math., 27 (2009), pp. 604--623]. Finally, an extensive set of numerical experiments demonstrates the robustness and scalability of our implementation on large-scale $H(div)$ problems with large jumps in the material coefficients.
Parallel Solver for H(div) Problems Using Hybridization and AMG
Energy Technology Data Exchange (ETDEWEB)
Lee, Chak S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2016-01-15
In this paper, a scalable parallel solver is proposed for H(div) problems discretized by arbitrary order finite elements on general unstructured meshes. The solver is based on hybridization and algebraic multigrid (AMG). Unlike some previously studied H(div) solvers, the hybridization solver does not require discrete curl and gradient operators as additional input from the user. Instead, only some element information is needed in the construction of the solver. The hybridization results in a H1-equivalent symmetric positive definite system, which is then rescaled and solved by AMG solvers designed for H1 problems. Weak and strong scaling of the method are examined through several numerical tests. Our numerical results show that the proposed solver provides a promising alternative to ADS, a state-of-the-art solver [12], for H(div) problems. In fact, it outperforms ADS for higher order elements.
Back to the Future: Personality and Assessment and Personality Development
Roberts, Brent W.
2009-01-01
In this essay I consider the future of personality development in light of the past effects of Personality and Assessment on the field of personality in general and personality development in particular. The essay is organized around 1) the effect of Mischel's book on the foundational theories informing personality development; 2) definitions of personality traits; 3) an alternative model of personality traits, described as the sociogenomic model of personality traits, that can bridge the div...
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Prahathees Eswaramoorthy
2014-08-01
Full Text Available Sporulation in the bacterium Bacillus subtilis is a developmental program in which a progenitor cell differentiates into two different cell types, the smaller of which eventually becomes a dormant cell called a spore. The process begins with an asymmetric cell division event, followed by the activation of a transcription factor, σF, specifically in the smaller cell. Here, we show that the structural protein DivIVA localizes to the polar septum during sporulation and is required for asymmetric division and the compartment-specific activation of σF. Both events are known to require a protein called SpoIIE, which also localizes to the polar septum. We show that DivIVA copurifies with SpoIIE and that DivIVA may anchor SpoIIE briefly to the assembling polar septum before SpoIIE is subsequently released into the forespore membrane and recaptured at the polar septum. Finally, using super-resolution microscopy, we demonstrate that DivIVA and SpoIIE ultimately display a biased localization on the side of the polar septum that faces the smaller compartment in which σF is activated.
Spectral mimetic least-squares method for div-curl systems
Gerritsma, Marc; Palha, Artur; Lirkov, I.; Margenov, S.
2018-01-01
In this paper the spectral mimetic least-squares method is applied to a two-dimensional div-curl system. A test problem is solved on orthogonal and curvilinear meshes and both h- and p-convergence results are presented. The resulting solutions will be pointwise divergence-free for these test
Design information verification (DIV) of closed geological repositories (SAGOR activity 3c)
International Nuclear Information System (INIS)
Myatt, J.
1998-02-01
Following IAEA Advisory and Consultants Group meetings in September 1988 and in May 1991 respectively an IAEA multi-national Support Programme Task was initiated to consider the 'Development of Safeguards for Final Disposal of Spent Fuel in Geological Repositories' (SAGOR). A 'Technical Coordination Committee' (TCC) was set up with invited representatives from those Member State Support Programmes wishing to be involved. The joint programme, through the TCC, was given the task of studying the safeguards requirements in: conditioning plant (where the spent fuel is prepared for transfer to the repository); operating repositories (i.e. those in which the fuel is being emplaced); closed repositories. At the first meeting of the TCC in Washington in July 1994 the UK undertook to provide a study of the Design Information Verification (DIV) required in all three areas. For this activity the requirements, techniques and procedures for the Design Information Verification (DIV) of closed repositories have been considered. In completing the study the findings reported for activities 1b/c and 2c (descriptions of a Model Repository and Potential Diversion Paths, respectively) have been used in formulating any conclusions reached. It is also debatable as to whether this activity is strictly speaking DIV or is one of surveillance. As undeclared access can only be made to the emplacement areas of the repository by altering the physical makeup of the surrounding area; i.e. physically changing the 'design' of the surrounding area, however, this is deemed to be DIV. Although the techniques used appear to be those of surveillance they are being applied in this case as the tools of DIV. As with any facility there are a number of stages in its lifetime. For the purposes of this report the operating life of a repository is defined as being the time from inception to when it is finally decommissioned and sealed with the ground surface returned to being a green field. The repository is
Energy Technology Data Exchange (ETDEWEB)
Borbulevych, Oleg Y.; Plumley, Joshua A.; Martin, Roger I. [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States); Merz, Kenneth M. Jr [University of Florida, Gainesville, Florida (United States); Westerhoff, Lance M., E-mail: lance@quantumbioinc.com [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States)
2014-05-01
Semiempirical quantum-chemical X-ray macromolecular refinement using the program DivCon integrated with PHENIX is described. Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein–ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.
Cleareye In-Ground and In-Concrete DIV Inspections: FY11 Final Report
Energy Technology Data Exchange (ETDEWEB)
Braatz, Brett G.; Tedeschi, Jonathan R.; Denslow, Kayte M.; Morra, Marino; Knopik, Clint D.; Severtsen, Ronald H.; Jones, Anthony M.; Lechelt, Wayne M.; McMakin, Douglas L.; Good, Morris S.; Sorensen, Jerry B.; Hall, Thomas E.
2012-01-23
This report summarizes the results of a series of feasibility testing studies for in-ground and in-concrete imaging/detection technologies including radar imaging and acoustic time-of flight method. The objectives of this project are: (1) Design Information Verification (DIV) Tools for In-Concrete Inspections - To determine the feasibility of using holographic radar imaging (HRI), radar imaging, and acoustic time-of-flight (TOF) non-destructive evaluation technologies to detect, locate and identify pipes and voids embedded in standard-density and high-density concrete walls that typify those the IAEA will need to verify during field inspections; (2) DIV Tools for In-Ground Inspections - To determine the feasibility of using HRI and radar imaging non-destructive evaluation technologies to detect, locate, and identify objects buried at various depths made of various materials (metal, plastic, wood, and concrete) and representing geometries that typify those the IAEA will need to verify during field inspections; and (3) Based on the results of the studies, recommend the next steps needed to realize fieldable tools for in-concrete and in-ground inspections (including detection of deeply buried polyvinyl chloride [PVC] pipes) that employ the technologies shown to be feasible.
Borbulevych, Oleg Y; Plumley, Joshua A; Martin, Roger I; Merz, Kenneth M; Westerhoff, Lance M
2014-05-01
Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein-ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.
A weak Galerkin least-squares finite element method for div-curl systems
Li, Jichun; Ye, Xiu; Zhang, Shangyou
2018-06-01
In this paper, we introduce a weak Galerkin least-squares method for solving div-curl problem. This finite element method leads to a symmetric positive definite system and has the flexibility to work with general meshes such as hybrid mesh, polytopal mesh and mesh with hanging nodes. Error estimates of the finite element solution are derived. The numerical examples demonstrate the robustness and flexibility of the proposed method.
Plegaria, Jefferson S; Dzul, Stephen P; Zuiderweg, Erik R P; Stemmler, Timothy L; Pecoraro, Vincent L
2015-05-12
De novo protein design is a biologically relevant approach that provides a novel process in elucidating protein folding and modeling the metal centers of metalloproteins in a completely unrelated or simplified fold. An integral step in de novo protein design is the establishment of a well-folded scaffold with one conformation, which is a fundamental characteristic of many native proteins. Here, we report the NMR solution structure of apo α3DIV at pH 7.0, a de novo designed three-helix bundle peptide containing a triscysteine motif (Cys18, Cys28, and Cys67) that binds toxic heavy metals. The structure comprises 1067 NOE restraints derived from multinuclear multidimensional NOESY, as well as 138 dihedral angles (ψ, φ, and χ1). The backbone and heavy atoms of the 20 lowest energy structures have a root mean square deviation from the mean structure of 0.79 (0.16) Å and 1.31 (0.15) Å, respectively. When compared to the parent structure α3D, the substitution of Leu residues to Cys enhanced the α-helical content of α3DIV while maintaining the same overall topology and fold. In addition, solution studies on the metalated species illustrated metal-induced stability. An increase in the melting temperatures was observed for Hg(II), Pb(II), or Cd(II) bound α3DIV by 18-24 °C compared to its apo counterpart. Further, the extended X-ray absorption fine structure analysis on Hg(II)-α3DIV produced an average Hg(II)-S bond length at 2.36 Å, indicating a trigonal T-shaped coordination environment. Overall, the structure of apo α3DIV reveals an asymmetric distorted triscysteine metal binding site, which offers a model for native metalloregulatory proteins with thiol-rich ligands that function in regulating toxic heavy metals, such as ArsR, CadC, MerR, and PbrR.
Analysis of biological spectrum of Divčibare flora
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Popović Ivana
2006-01-01
Full Text Available One of the essential analyses which is performed during the floristic study of a region is the analysis of the biological spectrum. The analysis of the biological spectrum of the flora includes the determination of the type of life form for each taxon described in the flora of the study region. If it is considered that life form is a specific structural-functional response to the environmental effects and the result of the adaptation during the species evolution, it is clear that the basic characteristics of the site are more or less reflected in any life form. This fact is confirmed by the analysis of the biological spectrum of Divčibare flora. The study results are in correlation with the results of the analysis of the biological spectrum of the flora of Serbia and the Balkan Peninsula.
Ishikawa, Kazuki; Matsuoka, Satoshi; Hara, Hiroshi; Matsumoto, Kouji
2017-10-18
The Min system, which inhibits assembly of the cytokinetic protein FtsZ, is largely responsible for positioning the division site in rod-shaped bacteria. It has been reported that MinJ, which bridges DivIVA and MinD, is targeted to the cell poles by an interaction with DivIVA, and that MinJ in turn recruits MinCD to the cell poles. MinC, however, is located primarily at active division sites at mid-cell when expressed from its native promoter. Surprisingly, we found that Bacillus subtilis MinD is located at nascent septal membranes and at an asymmetric site on lateral membranes between nascent septal membranes in filamentous cells lacking MinJ or DivIVA. Bacillus subtilis MinD has two amphipathic α-helices rich in basic amino acid residues at its C-terminus; one of these, named MTS1 here, is the counterpart of the membrane targeting sequence (MTS) in Escherichia coli MinD while the other, named MTS-like sequence (MTSL), is the nearest helix to MTS1. These amphipathic helices were located independently at nascent septal membranes in cells lacking MinJ or DivIVA, whereas elimination of the helices from the wild type protein reduced its localization considerably. MinD variants with altered MTS1 and MTSL, in which basic amino acid residues were replaced with proline or acidic residues, were not located at nascent septal membranes, indicating that the binding to the nascent septal membranes requires basic residues and a helical structure. The septal localization of MTSL, but not of MTS1, was dependent on host cell MinD. These results suggest that MinD is targeted to nascent septal membranes via its C-terminal amphipathic α-helices in B. subtilis cells lacking MinJ or DivIVA. Moreover, the diffuse distribution of MinD lacking both MTSs suggests that only a small fraction of MinD depends on MinJ for its localization to nascent septal membranes.
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Yassaei S
2007-01-01
Full Text Available Background and Aim: Unlike other bones of the head and neck, hyoid bone has no bony articulations. It is connected to mandible, cranium and pharynx through muscles and ligaments. During treatment with functional appliance in patients with class II div1 malocclusion, mandible is positioned in inferior and anterior direction. Regarding the relation between hyoid and mandibular bone, alterations of hyoid bone position can be a result of functional appliance therapy. The aim of this study was to evaluate the changes of hyoid bone position following treatment with Farmand functional appliance in patients with class II div 1 malocclusion. Materials and Methods: In this before-after clinical trial, 28 patients with class II div 1 malocclusion which were under treatment with Farmand functional appliance for 11 months were selected. Facial growth in vertical, normal or horizontal direction was determined by cephalometric measurement. Data were analyzed with Paired-t test to compare the differences of mean values pre and post treatment. Variance analysis was used to compare the three growth patterns. P<0.05 was considered as the limit of significance. Results: Hyoid bone shifted significantly forward in horizontal dimension (P<0.01 and non-significantly upward in vertical dimension. There was no significant difference among the three studied groups with respect to hyoid bone position alterations in horizontal dimension but significant difference was observed between horizontal and vertical growth pattern in vertical dimension (P<0.05. There was significant correlation between decrease of ANB angle and forward movement of hyoid bone. Conclusion: Based on the results of this study, treatment with Farmand functional appliance (Fa II leads to significant alterations in the position and anterior displacement of the hyoid bone.
Divórcio e funcionamento psicológico em adultos e crianças
Silva, Diogo Jorge Pereira do Vale Lamela da
2013-01-01
Tese de doutoramento em Psicologia (área de especialização de Psicologia Clínica) A presente dissertação foi orientada por dois enquadramentos teóricos: o modelo de Desenvolvimento Positivo da Personalidade na idade adulta (Staudinger & Bowen, 2010) e no modelo ecológico da coparentalidade (Feinberg, 2003). Objetivo: Este trabalho pretendeu responder a quatro objetivos. (1) Identificar variáveis sócio-demográficas, características do divórcio e indicadores personológicos qu...
Heister, Timo
2012-01-29
Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.
Heister, Timo; Rapin, Gerd
2012-01-01
Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.
Journal of Biosciences | Indian Academy of Sciences
Indian Academy of Sciences (India)
Home; Journals; Journal of Biosciences. Vidya Ramachandran. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 437-464. Epidemiological profile of India: Historical and contemporary perspectives · M D Gupte Vidya Ramachandran R K Mutatkar · More Details Abstract Fulltext PDF.
SiDIVS: Simple Detection of Inductive Vehicle Signatures with a Multiplex Resonant Sensor
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José J. Lamas-Seco
2016-08-01
Full Text Available This work provides a system capable of obtaining simultaneous inductive signatures of vehicles traveling on a roadway with minimal cost. Based on Time-Division Multiplexing (TDM with multiple oscillators, one for each inductive loop, the proposed system detects the presence of vehicles by means of a shift in the oscillation period of the selected loop and registers the signature of the detected vehicles by measuring the duration of a fixed number of oscillator pulses. In order to test the system in an actual environment, we implement a prototype that we denote as SiDIVS (Simple Detection of Inductive Vehicle Signatures and acquire different vehicle inductive signatures under real scenarios. We also test the robustness of the detector by simulating the effect of noise on the signature acquisition.
Journal of Genetics | Indian Academy of Sciences
Indian Academy of Sciences (India)
L. S. Shashidhara T. N. C. Vidya · More Details Abstract Fulltext PDF. Volume 96 Issue 3 July 2017 pp 491-504 Perspectives. Niche construction in evolutionary theory: the construction of an academic niche? MANAN GUPTA N. G. PRASAD SUTIRTH DEY AMITABH JOSHI T. N. C. VIDYA · More Details Abstract Fulltext PDF.
Resonance – Journal of Science Education | Indian Academy of ...
Indian Academy of Sciences (India)
Home; Journals; Resonance – Journal of Science Education. T N C Vidya. Articles written in Resonance – Journal of Science Education. Volume 20 Issue 7 July 2015 pp 617-627 General Article. Why So Toxic?: Venom Evolution in Animals · Pritha Kundu Srikant Venkitachalam T N C Vidya · More Details Fulltext PDF ...
Animais, divórcio e consequências jurídicas
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Camilo Henrique Silva
2015-07-01
Full Text Available http://dx.doi.org/10.5007/1807-1384.2015v12n1p102 O presente trabalho, por meio da pesquisa bibliográfica às leis, às decisões judiciais e à doutrina, tem por escopo trazer ao leitor, de maneira objetiva, as reflexões e o posicionamento do ordenamento jurídico brasileiro sobre o tema dos animais de estimação envolvidos em disputas de guarda no processo de divórcio. Nesse contexto, o escrito aborda a lei brasileira sobre guarda, direito de visita e alimentos, e sua utilização, por analogia, aos casos envolvendo animais de estimação, em razão da falta de norma específica. O texto retrata a tarefa dos magistrados e tribunais de se posicionarem nos casos levados a juízo e apresenta requisitos a serem observados para a decisão da lide, com vistas ao bem-estar e interesse do animal. Na disputa judicial pelos animais de estimação é legal a concessão da guarda e direito de visita aos cônjuges-tutores e a imposição de prestar alimentos ao animal.
Energy Technology Data Exchange (ETDEWEB)
Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)
2016-10-15
These affect the mechanical design of the fuel assembly components. And thus, appropriate structural design criteria should also be chosen to incorporate the specific design conditions of the SFR fuel assemblies. Among them, the temperature is one of the most crucial conditions to be concerned because the sodium coolant temperature is normally more than 500ºC which is much higher than that of the LWR (< 350ºC). This implies that a thermal creep should be significantly considered in the SFR fuel assembly mechanical design. In addition to the high temperature condition, an irradiation swelling is also an important behavior that the SFR fuel assembly material should accommodate. To incorporate the temperature and irradiation impacts, the material of the fuel assembly components is presently determined to be made of HT-9, the ferriticmartensitic steel. In this paper, the ASME Sec. III Div. 5 (referred to as ‘Div. 5’ hereinafter), which was developed for a ‘high temperature reactor’, is considered as one of the structural design criteria for the mechanical design of SFR fuel assemblies. In this paper, the stress intensity limits, S{sub m} and S{sub t} of HT-9 were built for the structural criteria of an SFR fuel assembly. S{sub m} is obtained from the ultimate strength. As for S{sub t}, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of S{sub mt}, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as S{sub mt} under the temperature about 470ºC which is relatively low temperature range and over 470ºC with relatively short time duration as 1000 hours. And the S{sub t} is adopted as Smt at over 470ºC and long time duration over 34800 hours, and over 520ºC and 10{sup 4} hours too. And at over 570ºC and 1000 hours, and at over 630ºC and 100 hours, S{sub t} is also adopted for S{sub mt}.
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Bussotti F
2012-12-01
Full Text Available The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe. FunDivEUROPE is a new project aiming at a deeper understanding of the role of forest diversity on ecosystem functions and service provisioning for society. This project combines three scientific platforms: experimental, exploratory and inventory. The exploratory platform is based on the observation of a broad range of properties, traits and ecological processes on a network of ca. 240 natural forest sites representing a gradient of tree species diversity in six focal regions of Europe (Spain, Italy, Germany, Poland, Finland and Romania. The Italian sites are located on the hills of central and Southern Tuscany and represent the category “thermophilous deciduous forest”. Almost one year of fieldwork was needed to select and characterize 36 plots measuring 30 x 30 m. Selection was based on criteria concerning tree mixtures and richness, structural parameters and main environmental variables. The main features of these sites are synthetically presented in this paper together with a short description of the project structure and scope. The aim is also to enhance dissemination of the potential implications for a sustainable forest management in Italy.
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Allahyar Geramy
2015-12-01
Full Text Available Background and Aims: Cl II malocclusion is one of the most common abnormalities in human societies and using a simple, affordable and accessible treatment that can be provided by general practitioners or specialists, to prevent future malocclusion complications is vital. Cl II malocclusion treatment using functional appliances such as twin block and anterior inclined bite plan have less cost, side effects and complications compared to fixed orthodontic or orthosurgery. Until now, the dentoskeletal changes resulting from the application of twin block and anterior inclined bite plan in patients with Class II malocclusion has not been evaluated. The objective of the present study was to assess the dentoskeletal changes following the use of twin-block functional appliance and inclined anterior bite plan in the patients with class II malocclusion div 1 during mixed dentition. Materials and Methods: In this retrospective cohort trial, 60 patients with the definitive diagnosis of Class II div. 1 malocclusion having ANB>2 and FMA angel between 20 and 30 and without any previous treatment or syndrome who were treated with twin-block or inclined anterior bite plan appliance were selected and their lateral cephalometries were traced before and after treatment. Selected distance and angular landmarks were measured on the cephalograms with the good reliability (ICC=0.953 and the changes occurred in the landmarks were statistically analyzed using Student t test. Results: Due to the increased mandibular growth, most of the landmarks experienced significant changes following the treatment with twin-block and inclined bite plan (P0.05, however, SNA (P=0.04, overjet (P=0.007 and wits appraisal (P=0.004 changed differently after using the appliances. Conclusion: Despite with most similarities of both twin-block and anterior inclined bite plan to correct class II div. 1 malocclusion, Due to the advantages of anterior inclined bite plan such as less size, good
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Diogo Lamela
2010-01-01
Full Text Available Neste artigo propõe-se uma contribuição da teoria da vinculação na compreensão dos processos de adaptação dos adultos ao seu divórcio e como a desvinculação ao ex-cônjuge interfere na coparentalidade pós-divórcio. Este artigo formula duas hipóteses teóricas. A primeira hipótese afirma que o divórcio, enquanto processo relacional, deve ser lido como um momento de perda que germina reacções psicológicas similares às experienciadas pelos viúvos, tal como descreve Bowlby no modelo de perda da figura de vinculação, estando dependente dos estilos de vinculação dos adultos. A segunda hipótese sustenta que a coparentalidade pós-divórcio é predita pelos estilos de vinculação e pela qualidade da reorganização da vinculação dos pais. Finalmente, uma integração teórica é apresentada, operacionalizada numa proposta de investigação futura neste domínio.In this article, it is proposed the contribution of the attachment theory for understanding adults' adjustment processes to their divorce and how detachment to ex-spouse can infer in co-parenting relationships after marital dissolution. This article makes two theoretical assumptions that focus on two dimensions. The first hypothesis states that the divorce, while a relational process, should be read as a moment of loss that germinates similar psychological reactions to those experienced by widows. Bowlby describes it in his model of loss of the attachment figure as dependent on attachment styles of divorced adults. The second hypothesis argues that the post-divorce co-parenting relationships are predicted by the attachment styles and by the quality of parents' attachment reorganization. At the end, a theoretical integration is built, based on a proposal for future research in this area.
As Bruxas no Divã: o desafio de ser criativo e ousar no ensino de artes
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Marcelo Rossa
2012-11-01
Este artigo relata o projeto “As Bruxas no Divã”, que consiste na produção de um filme no Instituto Estadual de Educação (IEE escola da rede estadual de ensino de SC. Nele introduziu-se a linguagem cinematográfica na Educação Infantil, contribuindo no processo de ensino e aprendizagem de Artes. O objetivo deste projeto foi desenvolver uma vivência dentro das diversas linguagens artísticas, bem como aguçar a reflexão sobre questões existenciais da vida. O projeto oportunizou a utilização de diversas linguagens artísticas bem como as novas tecnologias. A motivação para seu desenvolvimento foi à literatura e a produção de cinema amador infantil e se mostraram uma forma de comunicação apta a estabelecer interdisciplinaridade de várias áreas do conhecimento de forma criativa e harmoniosa.
O envolvimento parental após a separação/divórcio Parental involvement after separation/divorce
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Luciana Suárez Grzybowski
2010-01-01
Full Text Available Apoiados no modelo ecológico-contextual e no conceito de envolvimento parental, este artigo se propõe a discutir as práticas parentais de pais e mães separados/divorciados com seus filhos. Para tanto, foram pesquisados 234 sujeitos (117 pais/117 mães com filhos em idade escolar, que responderam o Inventário de Práticas Parentais. Tal instrumento avaliou o envolvimento parental em 5 áreas: envolvimento afetivo, envolvimento didático, envolvimento social, envolvimento disciplinar e responsabilidade. Os resultados evidenciam maior envolvimento materno do que paterno com os filhos após o divórcio, tanto direto (cuidados, interação quanto indireto (monitoramento, preocupação. A coabitação com a mãe mostrou ser uma variável significativa associada ao maior envolvimento dela em atividades no espaço privado/doméstico, enquanto os pais tiveram maior envolvimento no espaço público/social. Características contextuais (coabitação, freqüência de visitas e características dos pais (ocupação, escolaridade, questões afetivo-conjugais mostraram-se fortemente associadas ao envolvimento parental após o divórcio.Based on the ecological-contextual model and on the concept of parental involvement, this article proposes to discuss the parental practices of separated/divorced fathers and mothers towards their children. In order to do so, 234 subjects (117 fathers/117 mothers with children at school were interviewed via the Parental Practices Inventory. Such instrument evaluated the parental involvement in 5 areas: affective involvement, didactic involvement, social involvement, disciplinary involvement and, responsibility. The results showed greater maternal involvement with children after the divorce: direct (care, interaction and indirect (monitoring, preoccupation. The cohabitation with the mother revealed itself as a significant variable associated to her greater involvement with activities in the private/domestic environment while
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Rohit Mehrotra
2014-01-01
Full Text Available This case report describes the esthetic and functional rehabilitation of a female patient in her mid forties having Class II Div 1 malocclusion, anterior open bite and multiple missing molars, with orthodontics and implant prosthodontics. The patient had bilaterally missing upper first and third molars and lower first and second molars. Orthodontic treatment using skeletal anchorage was performed to retract and align the upper anteriors and correct the open bite. In the upper arch, first molar spaces were closed and no prosthesis was needed. In the lower arch, the anteriors and premolars were aligned and implants were placed bilaterally to replace the missing molars and provide proper occlusion with the upper posteriors. Significant improvement in the occlusion, smile and facial esthetics was achieved. This article highlights the importance of an interdisciplinary team approach for providing optimum treatment to many adult patients.
Pulmonary function tests in air conditioner users | Vidya ...
African Journals Online (AJOL)
Background: Modernization has been implicated in the pathogenesis of allergic airway diseases. House dust, mites, and indoor air pollutants have been reported to cause elevation of serum IgE levels and/or enhancement of eosinophil activity. A component of modern lifestyle is the intense use of air-conditioners (AC) that ...
Positive solutions for system of 2n-th order Sturm–Liouville ...
Indian Academy of Sciences (India)
1Department of Applied Mathematics, Andhra University,. Visakhapatnam 530 003, India. 2Department of Mathematics, Gayatri Vidya Parishad College of Engineering for Women ... boundary value problems for ordinary differential equations.
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Bhagat V
2016-06-01
Full Text Available Vidya Bhagat,1 Mainul Haque,2 Nordin Bin Simbak,1 Kamarudin Jaalam3 1Faculty of Medicine, Universiti Sultan Zainal Abidin, Jalan Sultan Mahmud, Kuala Terengganu, Malaysia; 2Faculty of Medicine and Defense Health, National Defence University of Malaysia, Kuala Lumpur, Malaysia; 3USM-KLE International Medical Program, Belgaum, Karnataka, India Abstract: Personality dimension negative emotionality is known to be associated with academic achievement. The present study focuses on the influence of negative emotionality (neuroticism on the medical students’ academic achievements. The main objective of this study was to ascertain the negative emotionality scores among the first year Malaysian medical students studying in Malaysia and India, further to find out the association between negative emotionality and their academic achievements. The current study sample includes 60 first year Malaysian medical students from Universiti Sultan Zainal Abidin, Malaysia, and USM-KLE IMP, Belgaum, India. They were selected by convenient sampling technique. The Medico-Psychological questionnaire was used to find out the negative emotionality scores among the students and these scores were compared with academic scores. The data were analyzed using SPSS- 20. Thus, the study result goes with the prediction that there is a significant correlation between academic achievement and negative emotionality. We concluded that negative emotionality has a negative impact on medical student’s academic achievement regardless of the fact whether they study in their own country or overseas. Keywords: academic achievement, negative emotionality, Malay, medical students, Malaysia
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BERNARDES Rodrigo de Castro
1997-01-01
Full Text Available A rotura de parede livre do ventrículo esquerdo (VE e a comunicação interventricular (CIV por rotura de septo são dois eventos catastróficos que podem complicar a evolução do infarto agudo do miocárdio (IAM. A oportunidade do tratamento cirúrgico, o acesso à CIV e a técnica cirúrgica ideal para o tratamento desta complicação são muito discutidos na literatura (1-5. Os resultados, porém, são quase unânimes: alta taxa de mortalidade. A rotura da parede posterior do ventrículo esquerdo pós troca da valva mitral (disjunção atrioventricular não é uma complicação rara, sendo quase sempre fatal (6, 7. O objetivo de nosso trabalho é discutir a alternativa de tratamento cirúrgico destas graves lesões, sem o manuseio direto do músculo cardíaco friável, necrozado. Desenvolvemos e testamos em animais (carneiros o dispositivo de isolamento ventricular (DIV. No período de 12/7/95 a 10/1/96, operamos 12 carneiros adultos para o implante do DIV. No primeiro período de aprendizado da técnica de implante e de desenvolvimento da prótese, operamos 7 animais, sem sucesso. No segundo período operamos 5 animais, já com o DIV completamente desenvolvido e com a técnica cirúrgica já padronizada; obtivemos sucesso com todos os animais, sobrevivendo com bom débito cardíaco, constatado ao ecocardiograma e à ventriculografia. Após 20 dias de sobrevida, os animais foram submetidos a ventriculografia e ecocardiografia. Observamos o completo isolamento da cavidade ventricular com o emprego do DIV, obtendo o tratamento provisório destas graves lesões.
Indian Academy of Sciences (India)
/reso/020/07/0617-0627. Keywords. Venom; evolution; snakes; natural selection; neutral processes. Author Affiliations. Pritha Kundu1 Srikant Venkitachalam1 T N C Vidya2. Evolutionary and Organismal Biology Unit at JNCASR, Bengaluru.
Journal of Biosciences | Indian Academy of Sciences
Indian Academy of Sciences (India)
Author Affiliations. M D Gupte1 Vidya Ramachandran1 R K Mutatkar2. National Institute of Epidemiology, Chetput, Chennai 600 031, India; Medical Anthropology, School of Health Sciences, University of Pune, Pune 411 007, India ...
Existence of positive solutions for the system of higher order two ...
Indian Academy of Sciences (India)
2Department of Mathematics, Gayatri Vidya Parishad College of Engineering ... In these applied settings, positive solutions are meaningful [1,9,13,21]. Due to ... In this paper, we shall consider the nonlinear system of differential equations,. ⎧.
Characteristics of disintegration of different emulsion nuclei by ...
Indian Academy of Sciences (India)
2Department of Applied Science (Physics), Vidya College of Engineering, ... ded nuclei, offers a great advantage to study the nuclear collisions of the same projectile ... This will also allow us to have an increased statistics of the sample.
International Nuclear Information System (INIS)
Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik
2017-01-01
In this paper, the stress intensity limits, Sm and St of HT-9 were built for the structural criteria of an SFR fuel assembly. Sm is obtained from the ultimate strength. As for St, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of Smt, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as Smt under the temperature about 470 .deg. C which is relatively low temperature range and over 470 .deg. C with relatively short time duration as 1000 hours. And the St is adopted as Smt at over 470 .deg. C and long time duration over 34800 hours, and over 520 .deg. C and 104 hours too. And at over 570 .deg. C and 1000 hours, and at over 630 .deg. C and 100 hours, St is also adopted for Smt. To use the present result as design criteria, a stringent examination needs to be carried out, because those are calculated from the formulae of HT-9 without an experimental validation. Therefore, an experimental work on the mechanical properties of HT-9 will be necessary.
Entrevista - Crise do Capital, disputa de destino e desafios para os trabalhadores
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Reinaldo Gonçalves
2010-05-01
Full Text Available <div>Desde 2007, temos acompanhado as notícias sobre a mais profunda crise dodiv> À Parte - Os Fundos de Pensão no Contexto da Financeirização Capitalista Directory of Open Access Journals (Sweden) Stefania Becattini Vaccaro 2010-05-01 Full Text Available <div>Este trabalho discute criticamente a expansão da previdência privadadiv> Proceedings – Mathematical Sciences | Indian Academy of Sciences Indian Academy of Sciences (India) Department of Applied Mathematics, Andhra University, Visakhapatnam 530 003, India; Department of Mathematics, Gayatri Vidya Parishad College of Engineering for Women, Madhurawada, Visakhapatnam 530 048, India; Department of Mathematics, Sri Prakash College of Engineering, Tuni 533 401, India ... Trabalho e Moradia na Periferia: para Uma Política Urbana Economicamente Orientada Directory of Open Access Journals (Sweden) Luciana Corrêa Lago 2010-05-01 Full Text Available <div>O artigo examina as conexões entre as mudanças no mundo dodiv> Directory of Open Access Journals (Sweden) Clarissa Raposo 2010-05-01 Full Text Available <div>o texto analisa a interface entre o paradigma dos direitos da infânciadiv> Relações Internacionais, Política Social e Combate à Pobreza Directory of Open Access Journals (Sweden) Ana Paula Ornellas Mauriel 2010-05-01 Full Text Available <div>o artigo objetiva demonstrar como as políticas sociais atuais vemdiv> A Survey for Assessment of Role of Pharmacist in Community Directory of Open Access Journals (Sweden) P Kapur 2009-12-01 Full Text Available <div>Objective: To assess the role of pharmacist in community setting & consumer’s perception in National Capitaldiv> Direito à Convivência Familiar de Crianças Abrigadas: o papel do Ministério Público Directory of Open Access Journals (Sweden) Lúcia Ferreira e Sávio Bittencourt 2010-05-01 Full Text Available <div>Partindo dos estudos que demonstram que é na família estruturadadiv> Positive solutions for system of 2n-th order Sturm–Liouville ... Indian Academy of Sciences (India) Author Affiliations. K R Prasad1 A Kameswara Rao2 B Bharathi2. Department of Applied Mathematics, Andhra University, Visakhapatnam 530 003, India; Department of Mathematics, Gayatri Vidya Parishad College of Engineering for Women, Madhurawada, Visakhapatnam 530 048, India ... Positive solutions for system of 2n-th order Sturm–Liouville ... Indian Academy of Sciences (India) 2016-08-26 Aug 26, 2016 ... Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 1 .... Department of Applied Mathematics, Andhra University, Visakhapatnam 530 003, India; Department of Mathematics, Gayatri Vidya Parishad College of Engineering for Women, Madhurawada ... Please take note of this change. Economia, Sociedade e Política na Construção de um Campo do Conhecimento: a Saúde Coletiva no Brasil Directory of Open Access Journals (Sweden) Silvia Gerschman 2010-05-01 Full Text Available <div>O objetivo do texto é mostrar que “Saúde Coletiva” constitui umdiv>