WorldWideScience

Sample records for vice versa early

  1. Spondyloarthropathies in Autoimmune Diseases and Vice Versa

    Science.gov (United States)

    Pérez-Fernández, Oscar M.; Mantilla, Rubén D.; Cruz-Tapias, Paola; Rodriguez-Rodriguez, Alberto; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel

    2012-01-01

    Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs (N = 148). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs (N = 1077) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren's syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6%). There were two patients presenting with SS in the SpA group (1.4%) and 5 patients with autoimmune thyroiditis (3.5%). The global prevalence of ADs in SpAs was 4.86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs. PMID:22400103

  2. Even at 4 months, a labial is a good enough coronal, but not vice versa.

    Science.gov (United States)

    Tsuji, Sho; Mazuka, Reiko; Cristia, Alejandrina; Fikkert, Paula

    2015-01-01

    Numerous studies have revealed an asymmetry tied to the perception of coronal place of articulation: participants accept a labial mispronunciation of a coronal target, but not vice versa. Whether or not this asymmetry is based on language-general properties or arises from language-specific experience has been a matter of debate. The current study suggests a bias of the first type by documenting an early, cross-linguistic asymmetry related to coronal place of articulation. Japanese and Dutch 4- and 6-month-old infants showed evidence of discrimination if they were habituated to a labial and then tested on a coronal sequence, but not vice versa. This finding has important implications for both phonological theories and infant speech perception research. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. The conversion of spring wheat into winter wheat and vice versa ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 35; Issue 2. The conversion of spring wheat into winter wheat and vice versa: false claim or Lamarckian inheritance? Xiuju Li Yongsheng Liu. Mini-review Volume 35 Issue 2 June 2010 pp 321-325 ...

  4. Time scales: from Nabla calculus to Delta calculus and vice versa via duality

    OpenAIRE

    Caputo, M. Cristina

    2009-01-01

    In this note we show how one can obtain results from the nabla calculus from results on the delta calculus and vice versa via a duality argument. We provide applications of the main results to the calculus of variations on time scales.

  5. Exploring the impact of a spatial data infrastructure on value-added resellers and vice versa

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2013-08-01

    Full Text Available stream_source_info Cooper_2013_ABSTRACT ONLY.pdf.txt stream_content_type text/plain stream_size 1359 Content-Encoding UTF-8 stream_name Cooper_2013_ABSTRACT ONLY.pdf.txt Content-Type text/plain; charset=UTF-8 Cartography... from Pole to Pole Lecture Notes in Geoinformation and Cartography 2014, pp 395-404 Exploring the Impact of a Spatial Data Infrastructure on Value- Added Resellers and Vice Versa Antony K. Cooper, Serena Coetzee, Petr Rapant, Dominique Laurent...

  6. Coexistence of Wormian Bones With Metopism, and Vice Versa, in Adult Skulls.

    Science.gov (United States)

    Cirpan, Sibel; Aksu, Funda; Mas, Nuket; Magden, Abdurrahman Orhan

    2016-03-01

    The aim of the study is to investigate coexistence of Wormian bones with metopism, and vice versa, in adult skulls. A total of 160 dry adult human skulls of unknown sex and ages were randomly selected from the Gross Anatomy Laboratory of Medical School of Dokuz Eylul University. The skulls were examined for presence of metopism, Wormian bones (WB), and coexistence of WBs with metopism and vice versa. Topographic distribution of the WBs was macroscopically evaluated within the skulls including metopism. The photographs were being taken with Canon 400B (55 mm objective). The frequency of metopism and WBs in 160 skulls is 7.50% (12/160) and 59.3% (95/160), respectively, P coexistence of WBs with metopism was found as 11 of 12 skulls (91.66%), whereas the incidence of coexistence of metopism with WBs was found as 11 of 95 skulls (11.58%), P coexistence of WBs with metopism (11/12, 91.66%) and coexistence of metopism with WBs (11/95, 11.58%). The factors leading to metopism may also lead to WBs, whereas that the factors leading to WBs may not lead to metopism.

  7. From geometry to algebra and vice versa: Realistic mathematics education principles for analyzing geometry tasks

    Science.gov (United States)

    Jupri, Al

    2017-04-01

    In this article we address how Realistic Mathematics Education (RME) principles, including the intertwinement and the reality principles, are used to analyze geometry tasks. To do so, we carried out three phases of a small-scale study. First we analyzed four geometry problems - considered as tasks inviting the use of problem solving and reasoning skills - theoretically in the light of the RME principles. Second, we tested two problems to 31 undergraduate students of mathematics education program and other two problems to 16 master students of primary mathematics education program. Finally, we analyzed student written work and compared these empirical to the theoretical results. We found that there are discrepancies between what we expected theoretically and what occurred empirically in terms of mathematization and of intertwinement of mathematical concepts from geometry to algebra and vice versa. We conclude that the RME principles provide a fruitful framework for analyzing geometry tasks that, for instance, are intended for assessing student problem solving and reasoning skills.

  8. M2 to D2 and vice versa by 3-Lie and Lie bialgebra

    Energy Technology Data Exchange (ETDEWEB)

    Aali-Javanangrouh, M.; Rezaei-Aghdam, A. [Azarbaijan Shahid Madani University, Department of Physics, Faculty of Science, Tabriz (Iran, Islamic Republic of)

    2016-11-15

    Using the concept of a 3-Lie bialgebra, which has recently been defined in arXiv:1604.04475, we construct a Bagger-Lambert-Gustavson (BLG) model for the M2-brane on a Manin triple of a special 3-Lie bialgebra. Then by using the correspondence and the relation between those 3-Lie bialgebra with Lie bialgebra, we reduce this model to an N = (4,4) WZW model (D2-brane), such that its algebraic structure is a Lie bialgebra with one 2-cocycle. In this manner by using the correspondence of the 3-Lie bialgebra and Lie bialgebra (for this special 3-Lie algebra) one can construct the M2-brane from a D2-brane and vice versa. (orig.)

  9. The bronchial response to mannitol is attenuated by a previous methacholine test: but not vice versa

    DEFF Research Database (Denmark)

    Gade, E.; Thomsen, S.F.; Porsbjerg, C.

    2009-01-01

    To examine the airway response to inhaled mannitol performed before or after a methacholine challenge test in a group of asthmatics with different levels of disease. A total of 48 asthmatics, 18-73 years of age, were included in the study. Two pairs of challenges were performed in a random order...... on two separate days >= 24 h apart: either with mannitol performed first on day one, followed >= 1 h by methacholine, and methacholine as the first on day two, followed >= 1 h by mannitol or vice versa. A questionnaire-based interview was performed and lung function, exhaled nitric oxide, skin prick test......, and blood eosinophil count were measured. A total of 44% of the asthmatics used inhaled corticosteroids and 48% were atopic. The airway response to mannitol was attenuated when mannitol was given after methacholine, compared with the response to mannitol when it was given first [log response dose ratio (RDR...

  10. Prevalence of Celiac Disease in Children with Autoimmune Hepatitis and vice versa.

    Science.gov (United States)

    Najafi, Mehri; Sadjadei, Nooshin; Eftekhari, Kambiz; Khodadad, Ahmad; Motamed, Farzaneh; Fallahi, Gholam-Hossain; Farahmand, Fatemeh

    2014-12-01

    Celiac disease is an autoimmune disorder in which the risk of autoimmune liver disease is high. Autoimmune hepatitis is a chronic and progressive entity and the risk of its being associated with other autoimmune disorders such as celiac disease is high also. The aim of this study was to determine the prevalence of celiac disease in patients with autoimmune hepatitis and vice versa. In a cross-sectional study children with autoimmune hepatitis underwent serological screening and endoscopy for celiac disease. In patients with celiac disease, serum aminotransferases were measured and, if abnormal, autoantibodies related to autoimmune hepatitis were checked and needle liver biopsy was performed. Of the 96 patients, 64 had autoimmune hepatitis and 32 celiac disease. Among patients with autoimmune hepatitis only three (4.7%) were compatible with celiac disease. In the group of patients with celiac disease, autoimmune hepatitis was confirmed in four (12.5%) cases. We consider important to state that 3.1% of this group had celiac hepatitis. Autoimmune liver disease is sometimes associated with latent celiac disease. Serological screening for celiac disease should be routinely done in patients with abnormal serum aminotransferases, particularly those with chronic liver disease. On the other hand, celiac disease is often accompanied by other autoimmune diseases, including autoimmune hepatitis.

  11. Turning Music Catalogues into Archives of Musical Scores – or Vice Versa: Music Archives and Catalogues Based on MEI XML

    DEFF Research Database (Denmark)

    Geertinger, Axel Teich

    2014-01-01

    metadata and fully-featured scores may be a way of overcoming some of these limitations and at the same time include catalogue data in the score and vice versa. The Music Encoding Initiative (MEI) offers a framework for such an approach based on XML files. The article discusses pros and cons...

  12. Randomized, Noncomparative, Phase II Trial of Early Switch From Docetaxel to Cabazitaxel or Vice Versa, With Integrated Biomarker Analysis, in Men With Chemotherapy-Naïve, Metastatic, Castration-Resistant Prostate Cancer.

    Science.gov (United States)

    Antonarakis, Emmanuel S; Tagawa, Scott T; Galletti, Giuseppe; Worroll, Daniel; Ballman, Karla; Vanhuyse, Marie; Sonpavde, Guru; North, Scott; Albany, Costantine; Tsao, Che-Kai; Stewart, John; Zaher, Atef; Szatrowski, Ted; Zhou, Wei; Gjyrezi, Ada; Tasaki, Shinsuke; Portella, Luigi; Bai, Yang; Lannin, Timothy B; Suri, Shalu; Gruber, Conor N; Pratt, Erica D; Kirby, Brian J; Eisenberger, Mario A; Nanus, David M; Saad, Fred; Giannakakou, Paraskevi

    2017-10-01

    Purpose The TAXYNERGY trial ( ClinicalTrials.gov identifier: NCT01718353) evaluated clinical benefit from early taxane switch and circulating tumor cell (CTC) biomarkers to interrogate mechanisms of sensitivity or resistance to taxanes in men with chemotherapy-naïve, metastatic, castration-resistant prostate cancer. Patients and Methods Patients were randomly assigned 2:1 to docetaxel or cabazitaxel. Men who did not achieve ≥ 30% prostate-specific antigen (PSA) decline by cycle 4 (C4) switched taxane. The primary clinical endpoint was confirmed ≥ 50% PSA decline versus historical control (TAX327). The primary biomarker endpoint was analysis of post-treatment CTCs to confirm the hypothesis that clinical response was associated with taxane drug-target engagement, evidenced by decreased percent androgen receptor nuclear localization (%ARNL) and increased microtubule bundling. Results Sixty-three patients were randomly assigned to docetaxel (n = 41) or cabazitaxel (n = 22); 44.4% received prior potent androgen receptor-targeted therapy. Overall, 35 patients (55.6%) had confirmed ≥ 50% PSA responses, exceeding the historical control rate of 45.4% (TAX327). Of 61 treated patients, 33 (54.1%) had ≥ 30% PSA declines by C4 and did not switch taxane, 15 patients (24.6%) who did not achieve ≥ 30% PSA declines by C4 switched taxane, and 13 patients (21.3%) discontinued therapy before or at C4. Of patients switching taxane, 46.7% subsequently achieved ≥ 50% PSA decrease. In 26 CTC-evaluable patients, taxane-induced decrease in %ARNL (cycle 1 day 1 v cycle 1 day 8) was associated with a higher rate of ≥ 50% PSA decrease at C4 ( P = .009). Median composite progression-free survival was 9.1 months (95% CI, 4.9 to 11.7 months); median overall survival was not reached at 14 months. Common grade 3 or 4 adverse events included fatigue (13.1%) and febrile neutropenia (11.5%). Conclusion The early taxane switch strategy was associated with improved PSA response rates

  13. RAN as a Predictor of Reading Skills, and Vice Versa: Results from a Randomised Reading Intervention

    Science.gov (United States)

    Wolff, Ulrika

    2014-01-01

    Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for…

  14. RAN as a predictor of reading skills, and vice versa: results from a randomised reading intervention.

    Science.gov (United States)

    Wolff, Ulrika

    2014-07-01

    Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for children with reading difficulties. It also investigates a possible reciprocal relationship between RAN and reading skills, and the possibility of enhancing RAN by intervention. These issues are addressed by examining longitudinal data from a randomised reading intervention study carried out in Sweden for 9-year-old children with reading difficulties (N = 112). The intervention comprised three main elements: training of phonics, reading comprehension strategies and reading speed. The analysis of the data was carried out using structural equation modelling. The results demonstrated that after controlling for autoregressive effects and non-verbal IQ, RAN predicts reading speed whereas phonemic awareness predicts reading comprehension and spelling. RAN was significantly enhanced by training and a reciprocal relationship between reading speed and RAN was found. These findings contribute to support the view that both phonemic awareness and RAN independently influence early phases of reading, and that both are possible to enhance by training.

  15. Fatness predicts decreased physical activity and increased sedentary time, but not vice versa: support from a longitudinal study in 8- to 11-year-old children

    DEFF Research Database (Denmark)

    Hjorth, M. F.; Chaput, J.-P.; Ritz, C.

    2014-01-01

    Objective: To examine independent and combined cross-sectional associations between movement behaviors (physical activity (PA), sedentary time, sleep duration, screen time and sleep disturbance) and fat mass index (FMI), as well as to examine longitudinal associations between movement behaviors......, and an increase in sedentary time (Pless than or equal to0.001), even in normal-weight children (Pless than or equal to0.03). Conclusion: Total PA, MVPA and sleep duration were independently associated with FMI, and combined associations of movement behaviors showed a synergistic effect with FMI....... In the longitudinal study design, a high FMI at baseline was associated with lower PA and higher sedentary time after 200 days but not vice versa, even in normal-weight children. Our results suggest that adiposity is a better predictor of PA and sedentary behavior changes than the other way around....

  16. Do sensitive parents foster kind children, or vice versa? Bidirectional influences between children's prosocial behavior and parental sensitivity.

    Science.gov (United States)

    Newton, Emily K; Laible, Deborah; Carlo, Gustavo; Steele, Joel S; McGinley, Meredith

    2014-06-01

    Bidirectional theories of social development have been around for over 40 years (Bell, 1968), yet they have been applied primarily to the study of antisocial development. In the present study, the reciprocal relationship between parenting behavior and children's socially competent behaviors were examined. Using the National Institute of Child Health and Development Study of Early Child Care data set (NICHD Early Child Care Research Network, 2005), bidirectional relationships between parental sensitivity and children's prosocial behavior were modeled using latent variables in structural equation modeling for mothers and fathers, separately. Children and their parents engaged in structured interactions when children were 54-month-olds, 3rd graders, and 5th graders, and these interactions were coded for parental sensitivity. At 3rd, 5th, and 6th grades, teachers and parents reported on children's prosocial behavior. Parental education and child gender were entered as covariates in the models. The results provide support for a bidirectional relationship between children's prosocial behavior and maternal sensitivity (but not paternal sensitivity) in middle childhood. The importance of using a bidirectional approach to examine the development of social competence is emphasized. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  17. Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa.

    Science.gov (United States)

    McLachlan, Sandra M; Rapoport, Basil

    2013-01-01

    Thyrotropin receptor (TSHR) antibodies that stimulate the thyroid (TSAb) cause Graves' hyperthyroidism and TSHR antibodies which block thyrotropin action (TBAb) are occasionally responsible for hypothyroidism. Unusual patients switch from TSAb to TBAb (or vice versa) with concomitant thyroid function changes. We have examined case reports to obtain insight into the basis for "switching." TBAb to TSAb switching occurs in patients treated with levothyroxine (LT4); the reverse switch (TBAb to TSAb) occurs after anti-thyroid drug therapy; TSAb/TBAb alterations may occur during pregnancy and are well recognized in transient neonatal thyroid dysfunction. Factors that may impact the shift include: (i) LT4 treatment, usually associated with decreased thyroid autoantibodies, in unusual patients induces or enhances thyroid autoantibody levels; (ii) antithyroid drug treatment decreases thyroid autoantibody levels; (iii) hyperthyroidism can polarize antigen-presenting cells, leading to impaired development of regulatory T cells, thereby compromising control of autoimmunity; (iv) immune-suppression/hemodilution reduces thyroid autoantibodies during pregnancy and rebounds postpartum; (v) maternally transferred IgG transiently impacts thyroid function in neonates until metabolized; (vi) a Graves' disease model involving immunizing TSHR-knockout mice with mouse TSHR-adenovirus and transfer of TSHR antibody-secreting splenocytes to athymic mice demonstrates the TSAb to TBAb shift, paralleling the outcome of maternally transferred "term limited" TSHR antibodies in neonates. Finally, perhaps most important, as illustrated by dilution analyses of patients' sera in vitro, TSHR antibody concentrations and affinities play a critical role in switching TSAb and TBAb functional activities in vivo. Switching between TBAb and TSAb (or vice versa) occurs in unusual patients after LT4 therapy for hypothyroidism or anti-thyroid drug treatment for Graves' disease. These changes involve

  18. Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Versa

    Science.gov (United States)

    Rapoport, Basil

    2013-01-01

    Background Thyrotropin receptor (TSHR) antibodies that stimulate the thyroid (TSAb) cause Graves' hyperthyroidism and TSHR antibodies which block thyrotropin action (TBAb) are occasionally responsible for hypothyroidism. Unusual patients switch from TSAb to TBAb (or vice versa) with concomitant thyroid function changes. We have examined case reports to obtain insight into the basis for “switching.” Summary TBAb to TSAb switching occurs in patients treated with levothyroxine (LT4); the reverse switch (TBAb to TSAb) occurs after anti-thyroid drug therapy; TSAb/TBAb alterations may occur during pregnancy and are well recognized in transient neonatal thyroid dysfunction. Factors that may impact the shift include: (i) LT4 treatment, usually associated with decreased thyroid autoantibodies, in unusual patients induces or enhances thyroid autoantibody levels; (ii) antithyroid drug treatment decreases thyroid autoantibody levels; (iii) hyperthyroidism can polarize antigen-presenting cells, leading to impaired development of regulatory T cells, thereby compromising control of autoimmunity; (iv) immune-suppression/hemodilution reduces thyroid autoantibodies during pregnancy and rebounds postpartum; (v) maternally transferred IgG transiently impacts thyroid function in neonates until metabolized; (vi) a Graves' disease model involving immunizing TSHR-knockout mice with mouse TSHR-adenovirus and transfer of TSHR antibody-secreting splenocytes to athymic mice demonstrates the TSAb to TBAb shift, paralleling the outcome of maternally transferred “term limited” TSHR antibodies in neonates. Finally, perhaps most important, as illustrated by dilution analyses of patients' sera in vitro, TSHR antibody concentrations and affinities play a critical role in switching TSAb and TBAb functional activities in vivo. Conclusions Switching between TBAb and TSAb (or vice versa) occurs in unusual patients after LT4 therapy for hypothyroidism or anti-thyroid drug treatment for Graves

  19. Del campo a la ciudad y vice-versa: elementos para la historia del movimiento garífuna en honduras

    Directory of Open Access Journals (Sweden)

    Olivier Cuisset

    2014-08-01

    Full Text Available Do campo para a cidade e vice-versa: elementos da história do movimento Garifuna em Honduras Este artigo propõe abordar à história da luta Garífuna em Honduras, centrando-se na fundação e posterior evolução da Organização Fraternal Negra de Honduras (OFRANEH, atualmente Federação do Povo Garífuna Hondurenho. Partimos da formação das primeiras organizações negras nas cidades da Costa Norte, desde a década de 1950 até a fundação da OFRANEH a finais dos anos 70, em contra o racismo e a discriminação imperantes e em vínculo com as migrações laborais e o auge do ativismo sindical. Tratamos de entender a evolução da OFRANEH nas duas décadas seguintes a partir de suas dinâmicas internas, da agudização da problemática territorial nas comunidades garífunas da costa, de uma transformação multicultural no âmbito estatal e o surgimento de um movimento étnico a nível nacional. Discutimos, por fim, as contradições do multiculturalismo neoliberal e suas consequências para o movimento indígena e garífuna, com relação a suas referências  identitárias, seus marcos ideológicos e suas estratégias políticas. Esse estudo busca sintetizar a informação existente, integrando elementos de reflexão e aportes de um trabalho de campo em curso desde 2011. Palavras chaves: Honduras; Garífuna; Movimento negro; Movimento indígena; Afrodescendente --- Este artículo propone un acercamiento a la historia de la lucha garífuna en Honduras, centrándose en la fundación y posterior evolución de la Organización Fraternal Negra de Honduras (OFRANEH, hoy Federación del pueblo garífuna hondureño. Partimos de la formación de las primeras organizaciones negras en las ciudades de la Costa Norte, desde la década de 1950 hasta la fundación de la OFRANEH a finales de los años 70, en contra del racismo y de la discriminación imperantes, y en vínculo con las migraciones laborales y el auge del activismo sindical. Tratamos de

  20. Examining Sexual Assault Victimization and Loneliness as Risk Factors Associated With Nonlethal Self-Harm Behaviors in Female College Students: Is It Important to Control for Concomitant Suicidal Behaviors (and Vice Versa)?

    Science.gov (United States)

    Chang, Edward C; Lee, Jerin; Wright, Kaitlin M; Najarian, Alexandria S-M; Yu, Tina; Chang, Olivia D; Hirsch, Jameson K

    2016-10-01

    The present study examined sexual assault victimization and loneliness as predictors of self-harm behaviors in a sample of 224 female college students. Results from conducting regression analysis indicated that both sexual assault victimization and loneliness were unique and significant predictors of self-harm behaviors. This pattern remained even after controlling for concomitant suicidal behaviors. Interestingly, in a post hoc analysis predicting suicidal behaviors, it was found that loneliness, but not sexual assault victimization, was the only unique and significant predictor after controlling for self-harm behaviors. Some implications of the present findings for understanding self-harm behaviors in female college students and the importance of controlling for suicidal behaviors in studies of self-harm behaviors (and vice versa) are discussed.

  1. Clinical consequences of switching from olanzapine to risperidone and vice versa in outpatients with schizophrenia: 36-month results from the worldwide schizophrenia outpatients health outcomes (W-SOHO) study

    Science.gov (United States)

    2012-01-01

    Background With many atypical antipsychotics now available in the market, it has become a common clinical practice to switch between atypical agents as a means of achieving the best clinical outcomes. This study aimed to examine the impact of switching from olanzapine to risperidone and vice versa on clinical status and tolerability outcomes in outpatients with schizophrenia in a naturalistic setting. Methods W-SOHO was a 3-year observational study that involved over 17,000 outpatients with schizophrenia from 37 countries worldwide. The present post hoc study focused on the subgroup of patients who started taking olanzapine at baseline and subsequently made the first switch to risperidone (n=162) and vice versa (n=136). Clinical status was assessed at the visit when the first switch was made (i.e. before switching) and after switching. Logistic regression models examined the impact of medication switch on tolerability outcomes, and linear regression models assessed the association between medication switch and change in the Clinical Global Impression-Schizophrenia (CGI-SCH) overall score or change in weight. In addition, Kaplan-Meier survival curves and Cox-proportional hazards models were used to analyze the time to medication switch as well as time to relapse (symptom worsening as assessed by the CGI-SCH scale or hospitalization). Results 48% and 39% of patients switching to olanzapine and risperidone, respectively, remained on the medication without further switches (p=0.019). Patients switching to olanzapine were significantly less likely to experience relapse (hazard ratio: 3.43, 95% CI: 1.43, 8.26), extrapyramidal symptoms (odds ratio [OR]: 4.02, 95% CI: 1.49, 10.89) and amenorrhea/galactorrhea (OR: 8.99, 95% CI: 2.30, 35.13). No significant difference in weight change was, however, found between the two groups. While the CGI-SCH overall score improved in both groups after switching, there was a significantly greater change in those who switched to olanzapine

  2. Sociology as Moral Philosophy (and Vice Versa).

    Science.gov (United States)

    Vandenberghe, Frédéric

    2017-11-01

    In this article, I want to make an attempt to reconnect sociology to moral philosophy and moral philosophy to sociology. The thesis I want to defend is that sociology continues by other means the venerable tradition of practical and moral philosophy. Like its forebears, it stands and falls with a defense of "practical wisdom" (Aristotle) and "practical reason" (Kant). The development of a moral sociology presupposes, however, that one recognizes and rejects Max Weber's theory of axiological neutrality as an extremist position and that one carefully articulates prescriptive and descriptive, internal and external, as well as observer and actor positions. © 2017 Canadian Sociological Association/La Société canadienne de sociologie.

  3. Video2Sentence and Vice Versa

    Science.gov (United States)

    2013-10-25

    which outperforms a low-level audiovisual representation. Our novelty is to demonstrate the capabilities of semantic representations for translating ...demonstrate the translations using arbi- trary web videos and sentences related to everyday events. What is more, we will provide an automatically generated...explanation, in terms of concept detectors, on why a partic- ular video or sentence has been retrieved as the most likely translation . Categories and

  4. Do psychological factors help to reduce body mass in obesity or is it vice versa? Selected psychological aspects and effectiveness of the weight-loss program in the obese patients

    Directory of Open Access Journals (Sweden)

    Monika Bąk-Sosnowska

    2013-03-01

    Full Text Available The aim of this study was to assess the strength and direction of the correlation between cognitive appraisal, emotional state, social functioning and the effectiveness of a weight-loss program undertaken by obese subjects. The out-patient weight-loss program encompassed 150 obese women. Assessments were carried out at four time points: at the start of the weight-loss program and then after a 5%, 10% and a 15% reduction of the initial body mass. The research tools used were: a survey, the Situation Appraisal Questionnaire (SAQ, the Emotional State Questionnaire (ESQ, and the Q-Sort Social Functioning Questionnaire. The cognitive appraisal, emotional state and social functioning of the study group changed significantly (P<0.001. Significantly more individuals with a 15% body mass reduction, as compared with individuals with no body mass reduction, had an early obesity onset, i.e. at the age of <10 years old (P<0.001. Significantly more individuals with no body mass reduction, compared with individuals with a 15% reduction, had a later obesity onset, i.e. between the ages of 20 and 30 (P<0.001 and between 50 and 60 (P<0.001. Significantly more individuals with a 15% body mass reduction, compared with individuals with no mass reduction, had previously experienced the jojo effect (P<0.001 and had successfully lost weight (P<0.001. Significantly more individuals with no body mass reduction, compared with individuals with a15% reduction, had a history of unsuccessful attempts at reducing body mass (P<0.001. We conclude that the attitude of obese patients towards a weight-loss program is not a deciding factor for its effectiveness. As body mass reduces, the attitude improves.

  5. From substance use to homelessness or vice versa?

    Science.gov (United States)

    McVicar, Duncan; Moschion, Julie; van Ours, Jan C

    2015-07-01

    Homelessness is associated with substance use, but whether substance use precedes or follows homelessness is unclear. We investigate the nature of the relationship between homelessness and substance use using data from the unique Australian panel dataset Journeys Home collected in 4 surveys over the period from October 2011 to May 2013. Our data refer to 1325 individuals who were homeless or at risk of becoming homeless. We investigate dynamics in homelessness and substance use over the survey period. We find that the two are closely related: homeless individuals are more likely to be substance users and substance users are more likely to be homeless. These relationships, however, are predominantly driven by observed and unobserved individual characteristics which cause individuals to be both more likely to be homeless and to be substance users. Once we take these personal characteristics into account it seems that homelessness does not affect substance use, although we cannot rule out that alcohol use increases the probability that an individual becomes homeless. These overall relationships also hide some interesting heterogeneity by 'type' of homelessness. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. From substance use to homelessness or vice versa?

    NARCIS (Netherlands)

    McVicar, Duncan; Moschion, Julie; van Ours, Jan

    Homelessness is associated with substance use, but whether substance use precedes or follows homelessness is unclear. We investigate the nature of the relationship between homelessness and substance use using data from the unique Australian panel dataset Journeys Home collected in 4 surveys over the

  7. Why cognitive science needs philosophy and vice versa.

    Science.gov (United States)

    Thagard, Paul

    2009-04-01

    Contrary to common views that philosophy is extraneous to cognitive science, this paper argues that philosophy has a crucial role to play in cognitive science with respect to generality and normativity. General questions include the nature of theories and explanations, the role of computer simulation in cognitive theorizing, and the relations among the different fields of cognitive science. Normative questions include whether human thinking should be Bayesian, whether decision making should maximize expected utility, and how norms should be established. These kinds of general and normative questions make philosophical reflection an important part of progress in cognitive science. Philosophy operates best, however, not with a priori reasoning or conceptual analysis, but rather with empirically informed reflection on a wide range of findings in cognitive science. Copyright © 2009 Cognitive Science Society, Inc.

  8. Do depressive symptoms predict paranoia or vice versa?

    Science.gov (United States)

    Moritz, Steffen; Göritz, Anja S; McLean, Benjamin; Westermann, Stefan; Brodbeck, Jeannette

    2017-09-01

    Affective versus nonaffective psychoses are today no longer regarded as mutually exclusive disorders. Theorists have recently highlighted the role of affective symptoms in the formation of paranoid beliefs, particularly negative beliefs about the self, interpersonal sensitivity, sleep disturbances, and worrying, which exist along a continuum in the general population. For the present study, we tested the bidirectional causal relationships between paranoia and affect. A large population sample (N = 2,357) was examined at three time-points (baseline, six months, two years) as to the severity of subclinical paranoid beliefs (Paranoia Checklist, PCL) and depressive symptoms (Patient Health Questionnaire-9, PHQ-9). Worrying and avoidance were measured with items from the Maladaptive and Adaptive Coping Style Questionnaire (MAX). Depression and paranoid symptoms were strongly cross-sectionally related (r = 0.69) and showed high stability (r > 0.72). Depressive symptoms at T2 predicted paranoid symptoms at T3 (beta = 0.16; no significant relationship from T1 to T2), whereas paranoid symptoms predicted depressive symptoms from T1 to T2 (beta = 0.09; no significant relationship from T2 to T3). Results should be replicated in a sample of paranoid patients, as risk factors for subclinical versus manifest paranoia may differ. Some constructs were measured with single items derived from a new scale. The predictive association of depression to subsequent paranoia was small and confined to the long interval from T2 to T3. Treatments should target both paranoia and depression - irrespective of their causal relationship - particularly as patients with psychosis consider treatment of their emotional problems a priority. Copyright © 2016. Published by Elsevier Ltd.

  9. Adapting computational text analysis to social science (and vice versa

    Directory of Open Access Journals (Sweden)

    Paul DiMaggio

    2015-11-01

    Full Text Available Social scientists and computer scientist are divided by small differences in perspective and not by any significant disciplinary divide. In the field of text analysis, several such differences are noted: social scientists often use unsupervised models to explore corpora, whereas many computer scientists employ supervised models to train data; social scientists hold to more conventional causal notions than do most computer scientists, and often favor intense exploitation of existing algorithms, whereas computer scientists focus more on developing new models; and computer scientists tend to trust human judgment more than social scientists do. These differences have implications that potentially can improve the practice of social science.

  10. The Role of Neurosciences in Education… and vice versa

    Science.gov (United States)

    Gruart, Agnès

    2014-01-01

    One of the key questions in education is how the learning process in the classroom takes place and how different environmental and individual circumstances (attention, motivation, nutrition, stimulus presentation, etc.) can enhance the child's capabilities to learn and to remember. These and other cognitive skills are shaped as a consequence of…

  11. Text Mining to Support Gene Ontology Curation and Vice Versa.

    Science.gov (United States)

    Ruch, Patrick

    2017-01-01

    In this chapter, we explain how text mining can support the curation of molecular biology databases dealing with protein functions. We also show how curated data can play a disruptive role in the developments of text mining methods. We review a decade of efforts to improve the automatic assignment of Gene Ontology (GO) descriptors, the reference ontology for the characterization of genes and gene products. To illustrate the high potential of this approach, we compare the performances of an automatic text categorizer and show a large improvement of +225 % in both precision and recall on benchmarked data. We argue that automatic text categorization functions can ultimately be embedded into a Question-Answering (QA) system to answer questions related to protein functions. Because GO descriptors can be relatively long and specific, traditional QA systems cannot answer such questions. A new type of QA system, so-called Deep QA which uses machine learning methods trained with curated contents, is thus emerging. Finally, future advances of text mining instruments are directly dependent on the availability of high-quality annotated contents at every curation step. Databases workflows must start recording explicitly all the data they curate and ideally also some of the data they do not curate.

  12. The Specific Challenges of Globalization for Teaching and Vice Versa.

    Science.gov (United States)

    Smith, David Geoffrey

    2000-01-01

    Contemporary globalization is a continuation of European colonialism, shaped by the Protestant capitalist ethic and technology. The changing mandates of teaching and education under the influence of globalization are identified. Possibilities for teaching in the age of globalization are explored under three themes: recovery of personal truth,…

  13. From Law to Urban Legend, and Vice Versa: Creative Food Counterfeiting in Early Modern Spain / De la ley a la leyenda urbana y viceversa: falsificaciones de la cocina creativa en la España del Siglo de Oro

    Directory of Open Access Journals (Sweden)

    Elena del Río Parra

    2012-04-01

    Full Text Available ABSTRACT. This text takes on common urban legends related to food forgery in order to find ground in legal texts. While literature is keen on food counterfeiting and perpetuates common to- pics, there seems to be more than a taste for lite- rary expression: town cries and ordinances are eloquent in pointing out elaborate methods to manipulate certain foods, some of which coincide to what were believed to be cultural myths. RESUMEN. Este texto se aproxima a conocidas leyendas urbanas relacionadas con la falsificación de alimentos para encontrar su base en textos legales. Si bien en la literatura son frecuentes las menciones a comida manipulada, estas parecen ser más que una repetición de lugares comunes: pregones y ordenanzas abundan en métodos muy elaborados de alteración de ciertos alimentos, algunos de los cuales coinciden con lo que hasta ahora entendíamos como mitos culturales.

  14. Vice Presidents' Foreword

    Science.gov (United States)

    Dear Reader, In the early sixties, the eminent American hydrologist, Walter Langbein, founded Water Resources Research on behalf of the Section of Hydrology of the American Geophysical Union (AGU). Today, Water Resources Research is undisputed as the leading international journal in its field, and the key factors in its success are: * sustained emphasis on high quality papers; * the reviewing, editing, and management processes are all controlled by the scientists; * the allegiance of the AGU community to WRR; * a verv reasonable cost both to institutions and members; * financial benefits from the sales of the journal are fed back to the AGU, to the benefit of the members. In Europe, we now have a well established community of hydrologists in EGS, and the need for a high quality journal was addressed initially by adopting the already well established Elsevier journal of Hydrology as the official journal of the Hydrological Sciences Section. However, it became apparent that several of the factors associated with WRR's success were not working in the Society's favour, and so it has been decided to establish a new journal which, we hope, can emulate the success of WRR in the fullness of time. Much has been written over the past decade about the need to establish a strong identity for hydrology as a distinct geoscience alongside the atmospheric, ocean and solid earth sciences. The aims and scope of Hydrology and Earth System Sciences (HESS) have been designed to give full expression to this goal, and have been strongly influenced by 'Opportunities in the Hydrologic Sciences' (National Academy Press,1991). The functioning of the hydrological cycle within an earth system undergoing global change is currently the focus of research by many leading scientists and it is hoped that HESS will become a major forum for the publication and discussion of such research, as well as all new findings which enhance the position of hydrology as a geoscience. The success of a new journal

  15. Vice Presidents' Foreword

    Directory of Open Access Journals (Sweden)

    1997-01-01

    Full Text Available Dear Reader, In the early sixties, the eminent American hydrologist, Walter Langbein, founded Water Resources Research on behalf of the Section of Hydrology of the American Geophysical Union (AGU. Today, Water Resources Research is undisputed as the leading international journal in its field, and the key factors in its success are: * sustained emphasis on high quality papers; * the reviewing, editing, and management processes are all controlled by the scientists; * the allegiance of the AGU community to WRR; * a verv reasonable cost both to institutions and members; * financial benefits from the sales of the journal are fed back to the AGU, to the benefit of the members. In Europe, we now have a well established community of hydrologists in EGS, and the need for a high quality journal was addressed initially by adopting the already well established Elsevier journal of Hydrology as the official journal of the Hydrological Sciences Section. However, it became apparent that several of the factors associated with WRR's success were not working in the Society's favour, and so it has been decided to establish a new journal which, we hope, can emulate the success of WRR in the fullness of time. Much has been written over the past decade about the need to establish a strong identity for hydrology as a distinct geoscience alongside the atmospheric, ocean and solid earth sciences. The aims and scope of Hydrology and Earth System Sciences (HESS have been designed to give full expression to this goal, and have been strongly influenced by 'Opportunities in the Hydrologic Sciences' (National Academy Press,1991. The functioning of the hydrological cycle within an earth system undergoing global change is currently the focus of research by many leading scientists and it is hoped that HESS will become a major forum for the publication and discussion of such research, as well as all new findings which enhance the position of hydrology as a geoscience. The success

  16. Message from Vice-Chancellor

    Science.gov (United States)

    Nasir Ibrahim, Daing

    2013-12-01

    Salam Malaysia! First and foremost, I want to thank all 2nd International Conference on Mechanical Engineering Research (ICMER 2013) organisers for inviting me to address and officiate this conference. This 2nd ICMER 2013 provides a platform to bring together not only researchers, postgraduate students but also industrial people. With this platform, ICMER will embark on a whole process of making new discoveries and then translating them into products and services for the marketplace and this is only made possible with people like all of you. I would like to congratulate the ICMER 2013 organisers for the achievement of collecting 208 papers for this conference. Submissions received from 17 local universities, 7 industrial companies and 9 different countries is a great achievement for UMP. I am very happy to welcome all of you from Malaysia, Iran, Turkey, Japan, India, Australia, Ireland, Saudi Arabia and Bangladesh to this conference. As one of Malaysia's Public Universities, UMP's main challenge is to remain competitive and relevant by offering high quality technical academic programmes and research activities, focusing on its niche areas. New knowledge and findings cannot be generated without any research and development (R&D) activities. These efforts will undoubtedly generate lots of interesting results and new knowledge either bring further commercialisation activities. The Malaysian government has invested a huge sum of Ringgits in R&D over the years. Therefore, UMP must produce more quality researchers and graduates to ensure Malaysia reaps the returns from these investments vice versa of progressive economic growth for the country. UMP's 2011-2015 Strategic Plan determines to strengthen and sustained its financial support by allocating research grants and industry collaboration and consultations through its business and commercial unit. On behalf of UMP, I would like to express my appreciation to all committee members of ICMER 2013 from Faculty of Mechanical

  17. James Lyon. Miami Vice.

    Directory of Open Access Journals (Sweden)

    Chrysavgi Papayianni

    2011-04-01

    Full Text Available Despite the shortness of its length, Miami Vice by James Lyons is a meticulous study of NBC’s series of the same title, attempting to provide an overview of the show’s social, socio-cultural, and industrial-economic circumstances surrounding its production and distribution in order to highlight its status as a “defining show of its era” (3. The series starring Don Johnson as James Crocket and Philip Michael Thomas as Ricardo Tubbs appeared in 1984. As a continuation of the cop shows of the p...

  18. Effect van parodontale behandeling op reumatoïde artritis en vice versa

    NARCIS (Netherlands)

    de Smit, M J; Brouwer, E; Westra, J; Nesse, W; Vissink, A; van Winkelhoff, A J

    The pathogenesis of periodontitis and of rheumatoid arthritis show remarkable similarities. There is a distinct degree of co-existence between the 2 diseases. The prevalence of periodontitis is more pronounced in rheumatoid arthritis patients and the prevalence of rheumatoid arthritis is more

  19. Polymeric and Lipid Membranes-From Spheres to Flat Membranes and vice versa.

    Science.gov (United States)

    Saveleva, Mariia S; Lengert, Ekaterina V; Gorin, Dmitry A; Parakhonskiy, Bogdan V; Skirtach, Andre G

    2017-08-15

    Membranes are important components in a number of systems, where separation and control of the flow of molecules is desirable. Controllable membranes represent an even more coveted and desirable entity and their development is considered to be the next step of development. Typically, membranes are considered on flat surfaces, but spherical capsules possess a perfect "infinite" or fully suspended membranes. Similarities and transitions between spherical and flat membranes are discussed, while applications of membranes are also emphasized.

  20. Prominence Patterns in a Second Language : Intonational Transfer From Dutch to Spanish and Vice Versa

    NARCIS (Netherlands)

    van Maastricht, Lieke; Krahmer, Emiel; Swerts, Marc

    2015-01-01

    This research describes the production of prosodic cues to mark information structure in Spanish and Dutch. It compares speech by native (L1) and second language (L2) speakers and investigates prosodic transfer from the L1 to the L2, L2 proficiency as a factor in transfer effects, and transfer from

  1. Lattice discontinuities affecting the generation and annihilation of diffusible hydrogen and vice versa

    Science.gov (United States)

    Kirchheim, Reiner

    2017-06-01

    Lattice discontinuities include lattice defects and surfaces both providing traps for hydrogen atoms. It will be discussed under which conditions discontinuities of a given distribution either release trapped hydrogen to become diffusible or capture diffusible H-atoms to become trapped. It will be shown that for any distribution, the self-diffusion coefficient of hydrogen is determined by the product of the H-diffusion in the perfect lattice times the fraction of hydrogen being diffusible. In this context, the quantities diffusible hydrogen, lattice hydrogen, thermodynamic activity of hydrogen and chemical potential of hydrogen are interchangeable in a general way. New discontinuities are generated during hydrogen embritllement (fracture surfaces, voids, dislocations) and dislocations move by kink pair formation. The production rate of these discontinuities depends on the chemical potential of hydrogen within the defactant concept or the generalized Gibbs adsorption isotherm. Thus, the chemical potential of hydrogen determines both the amount of trapping and the defect generation rate. For a crack propagating by dislocations generation, the chemical potential affects its velocity independent of the accompanying concentration enhancement in front of the crack tip or the related adsorption on the freshly generated crack surface. This article is part of the themed issue 'The challenges of hydrogen and metals'.

  2. How Cultural Evolutionary Theory Can Inform Social Psychology and Vice Versa

    Science.gov (United States)

    Mesoudi, Alex

    2009-01-01

    Cultural evolutionary theory is an interdisciplinary field in which human culture is viewed as a Darwinian process of variation, competition, and inheritance, and the tools, methods, and theories developed by evolutionary biologists to study genetic evolution are adapted to study cultural change. It is argued here that an integration of the…

  3. Extensions of Lorentzian spacetime geometry: from Finsler to Cartan and vice versa

    CERN Document Server

    Hohmann, Manuel

    2013-01-01

    We briefly review two recently developed extensions of the Lorentzian geometry of spacetime and prove that they are in fact closely related. The first is the concept of observer space, which generalizes the space of Lorentzian observers, i.e., future unit timelike vectors, using Cartan geometry. The second is the concept of Finsler spacetimes, which generalizes the Lorentzian metric of general relativity to an observer-dependent Finsler metric. We show that every Finsler spacetime possesses a well-defined observer space that can naturally be equipped with a Cartan geometry. Conversely, we derive conditions under which a Cartan geometry on observer space gives rise to a Finsler spacetime. We further show that these two constructions complement each other. We finally apply our constructions to two gravity theories, MacDowell-Mansouri gravity on observer space and Finsler gravity, and translate their actions from one geometry to the other.

  4. Teaching Visual Arts - From the Innocent Eye to Immersiveness and Vice Versa

    Directory of Open Access Journals (Sweden)

    Marijan Richter

    2017-09-01

    Full Text Available In the mid-19th century, John Ruskin, apologist for the poetics of the innocent eye, advocated a break with academic Realism. A century later, Gombrich and Goodman criticized Ruskin's Romantic subjectivism from the position of High Modernism. Consequently, the "Enlightenment" approach in teaching visual arts became stronger. Recently, some teaching specialists have been trying to inaugurate the term, immersiveness, in place of visual arts language for the purpose of introducing contemporary art into the syllabus. This paper examines the relation between "the innocent eye myth" and topical approach of "immersiveness" within the framework of educational objectives and methods in contemporary teaching.

  5. Methylococcus capsulatus (Bath) from genome to protein function, and vice versa.

    Science.gov (United States)

    Karlsen, Odd A; Berven, Frode S; Bagstevold, June I; Larsen, Oivind; Jensen, Harald B

    2011-01-01

    The genome sequence of Methylococcus capsulatus (Bath), considered a model methylotroph, was published in 2004 [Ward, N., et al. (2004). Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath). PLoS Biol.2, e303]. In the postgenomic era, the challenge is to determine the gene function, and to this end, genomics must be complemented with proteomic approaches. This chapter describes some experimental and computational approaches we have used and developed for the exploration of the genome and proteome of M. capsulatus (Bath). Copyright © 2011 Elsevier Inc. All rights reserved.

  6. Do foreign greenfields outperform foreign acquisitions or vice versa? An institutional perspective

    NARCIS (Netherlands)

    Slangen, A.H.L.; Hennart, J.-F.

    2008-01-01

    Prior studies of the comparative performance of greenfields and acquisitions have advanced competing arguments, with some arguing that greenfields should outperform acquisitions because acquisitions are costlier to integrate, and others that acquisitions should outperform greenfields because

  7. How the melody facilitates the message and vice versa in infant learning and memory.

    Science.gov (United States)

    Thiessen, Erik D; Saffran, Jenny R

    2009-07-01

    Infants are often presented with input in which there are multiple related regularities, as is the case in musical input with both melodic and lyrical structure. Adult learners often learn more easily from complex input containing multiple correlated regularities than from simplified input. Do infants also capitalize on complexity, or instead do they benefit from simplified input? In this series of experiments, infants were presented with music in which melodic and lyrical structure predicted each other, or in which only one type of regularity was presented in isolation (melodies alone, or lyrics presented with no melody). Infants learned lyrics more easily when they were paired with a melody than when they were presented alone; similarly, they learned melodies more easily when they were paired with lyrics than when they were presented alone. There are several potential mechanisms that could explain how infants' learning is facilitated by complex input, suggesting important implications for learning in infants' natural environments.

  8. Self-Organisation in Spatial Systems-From Fractal Chaos to Regular Patterns and Vice Versa.

    Directory of Open Access Journals (Sweden)

    Michal Banaszak

    Full Text Available This study offers a new perspective on the evolutionary patterns of cities or urban agglomerations. Such developments can range from chaotic to fully ordered. We demonstrate that in a dynamic space of interactive human behaviour cities produce a wealth of gravitational attractors whose size and shape depend on the resistance of space emerging inter alia from transport friction costs. This finding offers original insights into the complex evolution of spatial systems and appears to be consistent with the principles of central place theory known from the spatial sciences and geography. Our approach is dynamic in nature and forms a generalisation of hierarchical principles in geographic space.

  9. Self-Organisation in Spatial Systems-From Fractal Chaos to Regular Patterns and Vice Versa.

    Science.gov (United States)

    Banaszak, Michal; Dziecielski, Michal; Nijkamp, Peter; Ratajczak, Waldemar

    2015-01-01

    This study offers a new perspective on the evolutionary patterns of cities or urban agglomerations. Such developments can range from chaotic to fully ordered. We demonstrate that in a dynamic space of interactive human behaviour cities produce a wealth of gravitational attractors whose size and shape depend on the resistance of space emerging inter alia from transport friction costs. This finding offers original insights into the complex evolution of spatial systems and appears to be consistent with the principles of central place theory known from the spatial sciences and geography. Our approach is dynamic in nature and forms a generalisation of hierarchical principles in geographic space.

  10. Mobile operators as banks or vice-versa? and: the challenges of Mobile channels for banks

    NARCIS (Netherlands)

    L-F. Pau (Louis-François)

    2004-01-01

    textabstractThis short paper addresses the strategic challenges of deposit banks, and payment clearinghouses, posed by the growing role of mobile operators as collectors and payment agents of flow of cash for themselves and third parties. Through analysis and data analysis from selected operators ,

  11. What violent conflict tells us about media and place-making (and vice versa)

    DEFF Research Database (Denmark)

    Mollerup, Nina Grønlykke

    2018-01-01

    of the entanglements of people and things related to media, showing how media are emplaced in the phenomenological world in the same way that violence is. Doing so, the chapter sheds light on how media can contribute to opening up places to other places and thus influence movements of people and things in conflict.......The increasing mobility of media has in recent years led some scholars to argue for a decline in the significance of place in relation to media. This chapter argues for the importance of understanding media as vitally emplaced in the phenomenological world and it uses violent conflict to develop...... this point. Drawing on ethnographic fieldwork with information activists and journalists during the Egyptian uprising, this chapter contests understandings of media as doubling or making place insignificant. Rather, it develops an understanding of media as place-making to allow for an analysis...

  12. Sequential Ambidexterity in Practice : A Longitudinal study on shifts from exploration to exploitation and vice versa

    NARCIS (Netherlands)

    de Visser, Matthias; Faems, Dries; Visscher, Klaasjan; de Weerd-Nederhof, Petronella C.

    2017-01-01

    The poster shows highlights of a study aimed at providing in-depth insights into the dynamics of a growing organization’s exploration and exploitation levels, demonstrating how structural and individual factors change an organization’s exploration and exploitation over time. A fast-growing research

  13. Social neuroscience: understanding the pieces fosters understanding the whole and vice versa.

    Science.gov (United States)

    Cacioppo, John T

    2002-11-01

    Social science and neuroscience perspectives represent two ends of a continuum of levels of organization studied in psychology. Human behavior as a whole unfolds at social levels of organization, whereas much of the research in psychology has focused on cognitive and biological pieces of this whole. Recent evidence underscores the complementary nature of social, cognitive, and biological levels of analysis and how research integrating these levels can foster more comprehensive theories of the mechanisms underlying complex behavior and the mind. This research underscores the unity of psychology and the importance of retaining multilevel integrative research that spans molar and molecular levels of analysis.

  14. De invloed van endodontische afwijkingen op parodontale afwijkingen en vice versa

    NARCIS (Netherlands)

    Peters, L.B.

    2010-01-01

    Pathologisch gezien kan er een relatie bestaan tussen het endodontium en het parodontium in de vorm van een onnatuurlijke verbinding tussen de anatomische structuren. Bij de primaire endodontische laesie met secundaire parodontale component is dat een smalle pocket die als fistel voor het

  15. Should risk from medical imaging be assessed in the absence of benefit and vice versa?

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Louis K. [The University of Texas - Houston Medical School, Department of Diagnostic and Interventional Imaging, Houston, TX (United States)

    2014-10-15

    Diagnostic radiology has an image problem. In its effort to develop a better understanding of benefit-risk in medical radiology, data on potential risks associated with medical imaging have been welcomed into the medical community. As such, risk perspectives and mantras from the occupational health profession have been adopted and applied to patients. These perspectives often focus on risk with only casual, incidental, or no reference to the benefits experienced by patients. These occupational health viewpoints have accumulated over decades, have overshadowed a very limited perspective about the benefits of medical X-rays, and have become an integrated part of our profession. This review argues that the medical profession should abandon perspectives on risk that are adopted from occupational health professions and focus on perspectives that realistically focus on the medical benefit-risk for patients. (orig.)

  16. Impact of B physics on model building and vice versa an example

    CERN Document Server

    Matias, J

    2003-01-01

    We motivate that the start-up of the B factories has opened a new precision flavour physics era, with an important effect on model building. Using as an example a left-right model with spontaneous CP violation, we will show how the inclusion of the new experimental data on B physics observables, together with the old observables coming from kaon physics, has significantly widened our capacity to strongly constrain the parameter space up to the point to exclude models. On the contrary, using certain hypotheses, mainly concerning isospin, we discuss how theory may help us to `test' the data on charged, neutral and mixed $B \\to \\pi K$ decays once experimental errors will be reduced.

  17. Mobile operators as banks or vice-versa? and: the challenges of Mobile channels for banks

    OpenAIRE

    Pau, Louis-François

    2004-01-01

    textabstractThis short paper addresses the strategic challenges of deposit banks, and payment clearinghouses, posed by the growing role of mobile operators as collectors and payment agents of flow of cash for themselves and third parties. Through analysis and data analysis from selected operators , it is shown that mobile operators achieve as money flow handlers levels of efficiency , profitability ,and risk control comparable with deposit banks – Furthermore , the payment infrastructures dep...

  18. Are Horses Like Zebras, or Vice Versa? Children's Sensitivity to the Asymmetries of Directional Comparisons

    Science.gov (United States)

    Chestnut, Eleanor K.; Markman, Ellen M.

    2016-01-01

    Adults exhibit strong preferences when framing symmetrical relations. Adults prefer, for example, "A zebra is like a horse" to "A horse is like a zebra," and "The bicycle is near the building" to "The building is near the bicycle." This is because directional syntax requires more typical or prominent items…

  19. De l’alcool à l’écriture, et vice versa

    Directory of Open Access Journals (Sweden)

    Pascal Brissette

    2009-09-01

    Full Text Available De la coupe à la lettre, de l’alcool à l’inspiration, les points de passage sont multiples et de divers ordres. La chanson à boire et l’imagerie du poète exalté par le vin ne sont que les manifestations les plus familières, les plus attendues de cette association première entre alcool et écriture. La citation suivante, tirée de Panégyrique de Guy Debord, montre déjà que d’autres angles du problème sont à couvrir :Quoique ayant beaucoup lu, j’ai bu davantage. J’ai écrit beaucoup moins que la p...

  20. Developmental cognitive genetics: How psychology can inform genetics and vice versa

    Science.gov (United States)

    Bishop, Dorothy V. M.

    2006-01-01

    Developmental neuropsychology is concerned with uncovering the underlying basis of developmental disorders such as specific language impairment (SLI), developmental dyslexia, and autistic disorder. Twin and family studies indicate that genetic influences play an important part in the aetiology of all of these disorders, yet progress in identifying genes has been slow. One way forward is to cut loose from conventional clinical criteria for diagnosing disorders and to focus instead on measures of underlying cognitive mechanisms. Psychology can inform genetics by clarifying what the key dimensions are for heritable phenotypes. However, it is not a one-way street. By using genetically informative designs, one can gain insights about causal relationships between different cognitive deficits. For instance, it has been suggested that low-level auditory deficits cause phonological problems in SLI. However, a twin study showed that, although both types of deficit occur in SLI, they have quite different origins, with environmental factors more important for auditory deficit, and genes more important for deficient phonological short-term memory. Another study found that morphosyntactic deficits in SLI are also highly heritable, but have different genetic origins from impairments of phonological short-term memory. A genetic perspective shows that a search for the underlying cause of developmental disorders may be misguided, because they are complex and heterogeneous and are associated with multiple risk factors that only cause serious disability when they occur in combination. PMID:16769616

  1. MO-C-BRCD-03: The Role of Informatics in Medical Physics and Vice Versa.

    Science.gov (United States)

    Andriole, K

    2012-06-01

    Like Medical Physics, Imaging Informatics encompasses concepts touching every aspect of the imaging chain from image creation, acquisition, management and archival, to image processing, analysis, display and interpretation. The two disciplines are in fact quite complementary, with similar goals to improve the quality of care provided to patients using an evidence-based approach, to assure safety in the clinical and research environments, to facilitate efficiency in the workplace, and to accelerate knowledge discovery. Use-cases describing several areas of informatics activity will be given to illustrate current limitations that would benefit from medical physicist participation, and conversely areas in which informaticists may contribute to the solution. Topics to be discussed include radiation dose monitoring, process management and quality control, display technologies, business analytics techniques, and quantitative imaging. Quantitative imaging is increasingly becoming an essential part of biomedicalresearch as well as being incorporated into clinical diagnostic activities. Referring clinicians are asking for more objective information to be gleaned from the imaging tests that they order so that they may make the best clinical management decisions for their patients. Medical Physicists may be called upon to identify existing issues as well as develop, validate and implement new approaches and technologies to help move the field further toward quantitative imaging methods for the future. Biomedical imaging informatics tools and techniques such as standards, integration, data mining, cloud computing and new systems architectures, ontologies and lexicons, data visualization and navigation tools, and business analytics applications can be used to overcome some of the existing limitations. 1. Describe what is meant by Medical Imaging Informatics and understand why the medical physicist should care. 2. Identify existing limitations in information technologies with respect to Medical Physics, and conversely see how Informatics may assist the medical physicist in filling some of the current gaps in their activities. 3. Understand general informatics concepts and areas of investigation including imaging and workflow standards, systems integration, computing architectures, ontologies, data mining and business analytics, data visualization and human-computer interface tools, and the importance of quantitative imaging for the future of Medical Physics and Imaging Informatics. 4. Become familiar with on-going efforts to address current challenges facing future research into and clinical implementation of quantitative imaging applications. © 2012 American Association of Physicists in Medicine.

  2. 25 CFR 226.25 - Gas well drilled by oil lessees and vice versa.

    Science.gov (United States)

    2010-04-01

    ... the gas lessee does not, within 45 days after receiving notice and cost of drilling, elect to take over such well and reimburse the oil lessee the cost of drilling, including all damages paid and the... notice and cost of drilling, elect to take over the well, he/she must immediately notify the gas lessee...

  3. Learning Processes in a Work Organization: From Individual to Collective and/or Vice Versa?

    Science.gov (United States)

    Lehesvirta, Tuija

    2004-01-01

    The study investigates learning as knowledge-creation processes on individual and collective levels. The processes were examined in an ethnographic study, conducted in a metal industry company over a four-year period. The empirical study suggests that conflicts and crises experienced on individual level were some kind of incidental starting…

  4. Looking at men and masculinities through Information and Communication Technologies, and Vice Versa

    OpenAIRE

    Hearn, Jeff; Hall, Matthew

    2017-01-01

    The lecture series that led to this paper, “Gender-Effects: How Women create Technology of Tomorrow”, has an explicit focus on women. However, in this article in keeping with a relational approach to gender, we focus on men and masculinities, seen within the context of and gender power relations, and the diverse interrelations of men and masculinities with information and communication technologies (ICTs). This includes addressing to some of the shortcomings of contemporary studies of men and...

  5. Developmental cognitive genetics: how psychology can inform genetics and vice versa.

    Science.gov (United States)

    Bishop, Dorothy V M

    2006-07-01

    Developmental neuropsychology is concerned with uncovering the underlying basis of developmental disorders such as specific language impairment (SLI), developmental dyslexia, and autistic disorder. Twin and family studies indicate that genetic influences play an important part in the aetiology of all of these disorders, yet progress in identifying genes has been slow. One way forward is to cut loose from conventional clinical criteria for diagnosing disorders and to focus instead on measures of underlying cognitive mechanisms. Psychology can inform genetics by clarifying what the key dimensions are for heritable phenotypes. However, it is not a one-way street. By using genetically informative designs, one can gain insights about causal relationships between different cognitive deficits. For instance, it has been suggested that low-level auditory deficits cause phonological problems in SLI. However, a twin study showed that, although both types of deficit occur in SLI, they have quite different origins, with environmental factors more important for auditory deficit, and genes more important for deficient phonological short-term memory. Another study found that morphosyntactic deficits in SLI are also highly heritable, but have different genetic origins from impairments of phonological short-term memory. A genetic perspective shows that a search for the underlying cause of developmental disorders may be misguided, because they are complex and heterogeneous and are associated with multiple risk factors that only cause serious disability when they occur in combination.

  6. From Experience to Summit or Vice Versa? Netnography Study on a Virtual Community of Mountaineering

    Science.gov (United States)

    Kaya, Sabri; Argan, Metin; Yetim, Gözde

    2017-01-01

    Virtual communities have been a significant channel for people to share their feelings and experiences regarding a special issue. The combination of ethnography and the internet offers the opportunity for new methods of research that can potentially reach a broad audience in the online world. Thus, netnography, a combination of internet and…

  7. Polymeric and Lipid Membranes—From Spheres to Flat Membranes and vice versa

    Science.gov (United States)

    Saveleva, Mariia S.; Gorin, Dmitry A.; Skirtach, Andre G.

    2017-01-01

    Membranes are important components in a number of systems, where separation and control of the flow of molecules is desirable. Controllable membranes represent an even more coveted and desirable entity and their development is considered to be the next step of development. Typically, membranes are considered on flat surfaces, but spherical capsules possess a perfect “infinite” or fully suspended membranes. Similarities and transitions between spherical and flat membranes are discussed, while applications of membranes are also emphasized. PMID:28809796

  8. Federal mineral-lease-bidding data bases versus the real world and vice versa

    Energy Technology Data Exchange (ETDEWEB)

    Lohrenz, J.; Waller, R.A.

    1979-01-01

    From the vantage point of builders and operators of Federal mineral-lease-bidding data bases, users are addressed. Users are a polyglot lot of empiricists, mechanists, and theorists. The users' perfect data base would contain all data needed to examine all bidding theories and predict bidders' behavior using the theories. That ideal data base has not been attained. However, even the richly flawed history of these data bases leads one to the not particularly prescient notion that users, with omnipresent complaints about errors in and lack of data, will keep the data bases functioning by using them.

  9. What the Heart Says to the Brain (and vice versa and Why We Should Listen

    Directory of Open Access Journals (Sweden)

    Julian F. Thayer

    2007-12-01

    Full Text Available In the present paper we describe a model of neurovisceral integration in which a set of neural structures involved in cognitive, affective, and autonomic regulation are related to heart rate variability (HRV and cognitive performance. We will provide pharmacological and neuroimaging data in support of the neural structures linking the central nervous system to HRV. Next, we will review a number of studies from our group showing that individual differences in HRV are related to performance on tasks associated with executive function and prefrontal cortical activity as well as with emotional regulation. In the first study, individual differences in resting HRV we related to performance on executive and nonexecutive function tasks. The results showed that greater HRV was associated with better performance on executive function tasks. In another experiment, HRV was manipulated by physical detraining. Again, those that maintained their HRV at the post-test showed better performance on executive function tasks. In an experiment investigating emotional regulation we showed that resting levels of HRV were related to emotion modulated startle responses such that those with higher HRV produced context appropriate responses compared to those with low HRV. We propose that these findings have important implications for the understanding of the two-way communication between the heart and the brain.

  10. Oil Dependence, Climate Change and Energy Security: Will Constraints on Oil Shape our Climate Future or Vice Versa?

    Science.gov (United States)

    Mignone, B. K.

    2008-12-01

    Threats to US and global energy security take several forms. First, the overwhelming dependence on oil in the transport sector leaves the US economy (and others) vulnerable to supply shocks and price volatility. Secondly, the global dependence on oil inflates prices and enhances the transfer of wealth to authoritarian regimes. Finally, the global reliance on fossil fuels more generally jeopardizes the stability of the climate system. These three threats - economic, strategic and environmental - can only be mitigated through a gradual substitution away from fossil fuels (both coal and oil) on a global scale. Such large-scale substitution could occur in response to potential resource constraints or in response to coordinated government policies in which these externalities are explicitly internalized. Here, I make use of a well-known integrated assessment model (MERGE) to examine both possibilities. When resource limits are considered alone, global fuel use tends to shift toward even more carbon-intensive resources, like oil shale or liquids derived from coal. On the other hand, when explicit carbon constraints are imposed, the fuel sector response is more complex. Generally, less stringent climate targets can be satisfied entirely through reductions in global coal consumption, while more stringent targets require simultaneous reductions in both coal and oil consumption. Taken together, these model results suggest that resource constraints alone will only exacerbate the climate problem, while a subset of policy-driven carbon constraints may yield tangible security benefits (in the form of reduced global oil consumption) in addition to the intended environmental outcome.

  11. Does stress influence sleep patterns, food intake, weight gain, abdominal obesity and weight loss interventions and vice versa?

    Science.gov (United States)

    Geiker, N R W; Astrup, A; Hjorth, M F; Sjödin, A; Pijls, L; Markus, C Rob

    2018-01-01

    Decades of research have reported only weak associations between the intakes of specific foods or drinks and weight gain and obesity. Randomized controlled dietary intervention trials have only shown very modest effects of changes in nutrient intake and diet composition on body weight in obese subjects. This review summarizes the scientific evidence on the role mental stress (either in or not in association with impaired sleep) may play in poor sleep, enhanced appetite, cravings and decreased motivation for physical activity. All these factors contribute to weight gain and obesity, possibly via decreasing the efficacy of weight loss interventions. We also review evidence for the role that lifestyle and stress management may play in achieving weight loss in stress-vulnerable individuals with overweight. © 2017 World Obesity Federation.

  12. Impact of energy trading on O and M and vice versa; Wechselwirkung zwischen Energiehandel und O and M

    Energy Technology Data Exchange (ETDEWEB)

    Zauner, Rudolf [VERBUND Renewable Power GmbH, Wien (Austria)

    2013-11-01

    Wind energy is growing up, and in more and more markets is being traded the same as any other energy source. This imposes a number of challenges on the wind turbine operators. However, a comparison of various European countries shows that this is the way forward: a market-oriented subsidiary system is set to replace the inflexible feed-in tariffs. To trade wind energy, wind must be forecast as accurately as possible a day in advance in an at least hourly resolution. This leads to a decrease in balancing energy costs and plays a key role in bringing wind energy closer to the market. (orig.)

  13. The Picaresque Writer: What a Reading of Apuleius' Metamorphoses Can Tell about Lazarillo de Tormes (and Vice Versa

    Directory of Open Access Journals (Sweden)

    Zala Rott

    2009-12-01

    All in all, the one obvious thing is the transition from an oral form of expression to a (more elaborate written one: from a speech, fable, or story to a book, letter, or novel, where the real victim is the reader.

  14. Sleep quality predicts positive and negative affect but not vice versa. An electronic diary study in depressed and healthy individuals.

    Science.gov (United States)

    Bouwmans, Mara E J; Bos, Elisabeth H; Hoenders, H J Rogier; Oldehinkel, Albertine J; de Jonge, Peter

    2017-01-01

    The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated the temporal order of change in sleep and affect in participants with and without depression. 27 depressed patients and 27 pair-matched healthy controls assessed their sleep in the morning and their affect 3 times a day for 30 consecutive days in their natural environment. Daily sleep quality and average positive affect (PA) and negative affect (NA) were used to examine whether changes in sleep quality preceded or followed changes in PA and NA, and whether this was different for patients and healthy controls. Second, presumptive mediating factors were investigated. We hypothesized that fatigue mediated the effect of changes in sleep quality on subsequent PA/NA, and that rumination mediated the effect of changes in PA/NA on subsequent sleep quality. Multilevel models showed that changes in sleep quality predicted changes in PA (B=0.08, psleep quality and PA (Indirect Effect=0.03, psleep quality and NA (Indirect Effect=-0.02, p=0.01). Rumination was not investigated because of non-significant associations between PA/NA and sleep quality. The associations were not different for patients and controls. The analyses were restricted to self-reported sleep quality, and conclusions about causality could not be drawn. Improvements in sleep quality predicted improvements in affect the following day, partly mediated by fatigue. Treatment of sleep symptoms would benefit affect in clinical care and beyond. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Making Connections among Multiple Graphical Representations of Fractions: Sense-Making Competencies Enhance Perceptual Fluency, but Not Vice Versa

    Science.gov (United States)

    Rau, Martina A.; Aleven, Vincent; Rummel, Nikol

    2017-01-01

    Prior research shows that representational competencies that enable students to use graphical representations to reason and solve tasks is key to learning in many science, technology, engineering, and mathematics domains. We focus on two types of representational competencies: (1) "sense making" of connections by verbally explaining how…

  16. Asymmetrical transfer effects of cognitive bias modification: Modifying attention to threat influences interpretation of emotional ambiguity, but not vice versa.

    Science.gov (United States)

    Bowler, J O; Hoppitt, L; Illingworth, J; Dalgleish, T; Ononaiye, M; Perez-Olivas, G; Mackintosh, B

    2017-03-01

    It is well established that attention bias and interpretation bias each have a key role in the development and continuation of anxiety. How the biases may interact with one another in anxiety is, however, poorly understood. Using cognitive bias modification techniques, the present study examined whether training a more positive interpretation bias or attention bias resulted in transfer of effects to the untrained cognitive domain. Differences in anxiety reactivity to a real-world stressor were also assessed. Ninety-seven first year undergraduates who had self-reported anxiety were allocated to one of four groups: attention bias training (n = 24), interpretation bias training (n = 26), control task training (n = 25) and no training (n = 22). Training was computer-based and comprised eight sessions over four weeks. Baseline and follow-up measures of attention and interpretation bias, anxiety and depression were taken. A significant reduction in threat-related attention bias and an increase in positive interpretation bias occurred in the attention bias training group. The interpretation bias training group did not exhibit a significant change in attention bias, only interpretation bias. The effect of attention bias training on interpretation bias was significant as compared with the two control groups. There were no effects on self-report measures. The extent to which interpretive training can modify attentional processing remains unclear. Findings support the idea that attentional training might have broad cognitive consequences, impacting downstream on interpretive bias. However, they do not fully support a common mechanism hypothesis, as interpretive training did not impact on attentional bias. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. 50 Years of NOAA N. Hemisphere Snow Cover Analysis: Impact on NOAA NWP Forecasts and Vice Versa

    Science.gov (United States)

    Mitchell, K.; Helfrich, S.; Ramsay, B. H.; Baldwin, T.; Robinson, D. A.; Ek, M. B.; Zheng, W.; Dong, J.; Shimomura, D.

    2016-12-01

    This year 2016 marks the 50-year anniversary of the operational production of the NOAA Northern Hemisphere (NH) snow cover analysis. This presentation reviews how the need for information about NH snow cover in NOAA's numerical weather prediction (NWP) models motivated both 1) the initial production of the NH snow cover analysis and 2) evolutionary improvements in the spatial and temporal resolution of the analysis. NOAA began routine production of the NH snow cover analysis in 1966, then using only visible imagery from NOAA polar orbiting satellites, and later also applying time-lapse loops of visible imagery from geostationary satellites. From 1966 through 1997, this analysis was produced weekly on a 190-km grid spanning the Northern Hemisphere. The production of this analysis was carried out from the 1980's (or earlier) until 1997 by the NOAA NESDIS Satellite Analysis Branch (SAB). We review results from a key 1993 study by the National Meteorological Center (NMC, later named NCEP) that motivated the evolutionary advancement of the NH snow cover analysis from a weekly 190-km analysis to a daily, high resolution 4-km analysis in 1997. A hallmark of the new daily analysis was the use of additional satellite sources of snow cover information (such as automated retrievals of snow cover from polar orbiting microwave instruments), which spurred giving the analysis the new name of Interactive Multi-Sensor Snow (IMS). The introduction of the IMS coincided with the move of the operational production of the NH snow cover analysis from NESDIS/SAB to the joint Navy-NOAA National Ice Center (NIC) in Suitland, MD. Separate presentations in this session will focus on A) the advancements in the daily IMS analysis since 1997 and future plans for IMS improvements and B) use of the 50-year archive of the NOAA NH snow cover analysis as a Climate Date Record (CDR). We present a recent example of an NCEP Global Forecast System (GFS) forecast from 16 February 2015 illustrating how snow cover continues to play a pivotal role in the accuracy of NWP model forecasts of near-surface air temperature. Such forecasts continue to be very challenging for winter nighttime cases in high pressure regimes, which are often characterized by weak winds, clear skies and a very stable planetary boundary layer (PBL), which is intensified by the presence of snowpack.

  18. E-Scooters - Research encourages market development and vice versa; E-Scooters: Forschung belebt Marktentwicklung - und umgekehrt

    Energy Technology Data Exchange (ETDEWEB)

    Schwegler, U.

    2008-07-01

    This presentation made at the Swiss 2008 research conference on traffic by Urs Schwegler from the Swiss NewRide programme takes a look at the development of the market for electrically-driven bicycles and scooters and the market hindrances encountered. Various models including scooters, cross-country bikes and the novel Segway transporter are introduced and their advantages from the ecological point of view are examined. The E-Scooter programme is introduced and concepts for battery-charging stations are discussed. The results of test-days at various locations in Switzerland are examined. Four Action Programmes are introduced. The various actors involved and market development aspects are discussed, as are reliability, charging, promotional measures as well as energy and environmental aspects.

  19. The Arc from the Body to Culture: How Affect, Proprioception, Kinesthesia, and Perceptual Imagery Shape Cultural Knowledge (and vice versa

    Directory of Open Access Journals (Sweden)

    Michael Kimmel

    2013-06-01

    Full Text Available This essay approaches the complex triadic relation between concepts, body, and culture from an angle rooted in the empirical cognitive research of the past three decades or so. Specifically, it reviews approaches to how the body shapes conceptualization, reasoning, and communication. One main section examines how the body contributes to cultural learning and another how abstract cultural concepts are grounded in sensorimotor experience, perception, and inner somatic states. Their purpose is to survey and briefly critique different theoretical frameworks, probe into their complementarity, and summarily evaluate to what extent higher cognition is embodied. The third main section outlines elements of an epistemological framework that connects culture, concepts, and the body in a sensible way. The paper closes with a discussion of how the embodied cognition paradigm advances a rapprochement of different areas both within cognitive research and beyond.

  20. Language in schizophrenia Part 2: What can psycholinguistics bring to the study of schizophrenia...and vice versa?

    Science.gov (United States)

    Kuperberg, Gina R

    2010-08-01

    This is the second of two articles that discuss higher-order language and semantic processing in schizophrenia. The companion article (Part 1) gives an introduction to language dysfunction in schizophrenia patients. This article reviews a selection of psycholinguistic studies which suggest that sentence-level abnormalities in schizophrenia may stem from a relative overdependence on semantic associative relationships at the expense of building higher-order meaning. Language disturbances in schizophrenia may be best conceptualized as arising from an imbalance of activity across two streams of processing, one drawing upon semantic relationships within semantic memory and the other involving the use of combinatorial mechanisms to build propositional meaning. I will also discuss some of the ways in which the study of schizophrenia may offer new insights into the cognitive and neural architecture of the normal language system.

  1. How to calculate an MMSE score from a MODA score (and vice versa) in patients with Alzheimer's disease.

    Science.gov (United States)

    Cazzaniga, R; Francescani, A; Saetti, C; Spinnler, H

    2003-11-01

    The aim of the present study was to provide a statistically sound way of reciprocally converting scores of the mini-mental state examination (MMSE) and the Milan overall dementia assessment (MODA). A consecutive series of 182 patients with "probable" Alzheimer's disease patients was examined with both tests. MODA and MMSE scores proved to be highly correlated. A formula for converting MODA and MMSE scores was generated.

  2. The Importance of Evolutionary Theory for Developmental Science--And Vice Versa: The Case of Developmental Psychology

    Science.gov (United States)

    Greve, Werner

    2012-01-01

    The empirical and conceptual interrelations of phylogeny (evolution) and ontogeny (development) may prove to be more important than previously acknowledged. It is argued that this holds particularly for evolutionary psychology. For instance, an evolutionary point of view will add to the explanation of (the shape of) pre- and post-reductive phases…

  3. Putting Geography Education into Place: What Geography Educators Can Learn from Place-Based Education, and Vice Versa

    Science.gov (United States)

    Israel, Andrei L.

    2012-01-01

    In recent years, geography educators have sought to make their pedagogy relevant to pressing social and environmental issues, but these efforts have largely imported pedagogies from outside of geography. In place-based education, in contrast, place--one of geography's defining themes--serves as a central organizing principle for a socially…

  4. Effects of different land use changes on SOC stocks: From Mediterranean forest to agricultural land and vice versa

    Science.gov (United States)

    Lozano-García, Beatriz; Francaviglia, Rosa; Renzi, Gianluca; Doro, Luca; Parras-Alcántara, Luis; Ledda, Luigi; Concepción Benítez, M.

    2017-04-01

    During the past century there has been a general trend to alter ecosystems based on both the conversion from forest to agricultural land and the intensification of agriculture. The land use change (LUC) from forest to agricultural land is the origin of serious and direct soil problems, such as soil losses and degradation but there are other indirect problems as the decrease of soil carbon storage worldwide. Therefore, the deforestation involves an important loss of soil carbon, its emission to the atmosphere and a high contribution to the global warming. In addition, it is important to point out that due to the low yields and the high cost of modern tillage equipments, frequently the agricultural lands are abandoned, suffering a secondly LUC. This abandonment can exacerbate soil degradation, but in some cases gives the soil the opportunity to restore by revegetation (naturally in some cases, and induced in others). Thus, by reforestation/revegetation these soils can increase their capacity of storage soil organic carbon. To determine the effects both of deforestation and revegetation on SOC stock is highly important to consider the quantification of SOC stock in the hole profile, taking into account the surface layer and the subsurface horizons, since many research have shown the importance of the amount of C stored in depth and its significance in the role of soil as C sink. The main goal of this research was to assess the effect of a double LUC in the SOC stocks along the soil entire profile. After LUC from the agroforestry system to agricultural lands there were different situations. The first one in which the SOC stock did not suffer changes (when the land use was hay crop and pasture). There was no change in SOC stock both in the surface layer and in the subsurface. However, when the LUC was toward vineyards, both tilled and no tilled vineyards, the SOC stock decreased considerably in the topsoil. In the second land use change considered, derived from the abandonment of vineyards and the creation of semi-natural ecosystem, the SOC stock increased reaching values similar to the original Mediterranean forest. Therefore, in this case, the LUC resulted in the increase of SOC reaching in the long-term similar values to those initials.

  5. Impacts of Philosophy and Theology on the Discussions Concerning the Existence of ExoLife and Vice Versa

    Science.gov (United States)

    Kostro, Ludwik

    2012-05-01

    There are philosophers and theologians who argue in favor of the existence of life, consciousness and intelligence in the Universe. (A) Philosophers, to support their arguments, use e.g. (1) the principle of homogeneity of Nature ("The same natural or statistical phenomena in the same natural or statistical circumstances, run naturally or statistically the same way", "What is allowed by the laws of Nature has necessarily to happen if there are adequate and favorable circumstances"/George R. Price/). Therefore life and consciousness have been regarded as cosmic phenomena. (2) The principle of large numbers that allows us to calculate the frequency of replica, in our case the frequency of habitable exoplanets. (B) The theologians argue e.g. that if the Universe was deprived of life and consciousness, the act of creation could not be regarded as God's gift of sensible existence, but only as His toy to play with, deprived totally of sensibility. On the other hand the existence of exolife, especially of exo-civilisations, creates problems for Christian theology that is still geocentric i.e. provincial and parochial. According to the Christian beliefs in heaven there are governing only terrestrial representatives: Jesus of Nazareth who is sitting at the right-hand side of his Father, His Mother Mary who is considered to be the Queen of the Heaven and Saint Peter who holds the keys to the Kingdom of God. If in our and other galaxies there are habitable planets, then Christian theology must change. The Holy See is aware of the problem and therefore Rome encourages creation of new theological ideas. There are already theologians who, in order to make their theology more cosmic, try to resolve the problem introducing the notion of multi-incarnation or returning to the ancient adoptive Christology. In such a way the birth of the modern astrobiology can trigger a new profound overturn of people's outlook on the whole world.

  6. Does stress influence sleep patterns, food intake, weight gain, abdominal obesity and weight loss interventions and vice versa?

    DEFF Research Database (Denmark)

    Geiker, Nina Rica Wium; Astrup, Arne; Hjorth, Mads Fiil

    2018-01-01

    Decades of research have reported only weak associations between the intakes of specific foods or drinks and weight gain and obesity. Randomized controlled dietary intervention trials have only shown very modest effects of changes in nutrient intake and diet composition on body weight in obese...... subjects. This review summarizes the scientific evidence on the role mental stress (either in or not in association with impaired sleep) may play in poor sleep, enhanced appetite, cravings and decreased motivation for physical activity. All these factors contribute to weight gain and obesity, possibly via...

  7. « Nurseries of Vice and Folly » : Satires graphiques de l’opéra italien en Angleterre dans la première moitié du XVIIIe siècle “Nurseries of Vice and Folly”: Graphic Satires of Italian Opera in Early Eighteenth-Century Britain

    Directory of Open Access Journals (Sweden)

    Xavier Cervantes

    2009-11-01

    Full Text Available This article surveys several examples of visual, and especially graphic, satires of Italian opera in early eighteenth-century Britain. They often targeted other imported dramatic genres or non-dramatic types of entertainment, such as pantomime and masquerades; these were connected to Italian opera because of their immorality and the threat they posed to patriotism and national ethics. These images can be considered the visual equivalents of many contemporary printed satires and critiques. However, even if these documents are genuine iconotexts, including textual fragments under various guises, their iconic specificity enlarged the scope for various types of satirical discourse, as appears in the detailed study of a striking example of intericonicity.

  8. CERN welcomes the Spanish Vice-President

    CERN Multimedia

    Anaïs Schaeffer

    2015-01-01

    On 29 September, CERN had the pleasure of welcoming the Vice-President of the Government of Spain, Soraya Sáenz de Santamaría, for a visit of the Laboratory.   From left to right: Lluis Miralles (Head of the General Infrastructure Services department), Soraya Sáenz de Santamaría (Vice-President of the Government of Spain) and José Miguel Jiménez (Head of the Technology department).   The Vice-President was accompanied by Carmen Vela, Spanish Secretary of State for Research, Development and Innovation, Bernardo de Sicart Escoda, Ambassador of Spain to Switzerland, and Ana Menéndez Pérez, Permanent Representative of Spain to the United Nations and International Organizations in Geneva. Their tour started at LHC Point 1, where CERN Director-General Rolf Heuer welcomed them and gave them an introduction to CERN's activities. Jos&ea...

  9. VersaCold: Analysis of Change Management in Mergers & Acquisitions

    OpenAIRE

    Eslami, Sara

    2011-01-01

    Many firms use mergers and acquisitions as a corporate strategy to increase shareholder value. Therefore, understanding such a widely exercised strategy and its implications on corporate change would be critical for organizations that wish to pursue this strategy. This study provides an in depth review of mergers and acquisitions and introduces best practices for managing changes that result from mergers and acquisitions. Next, the concepts are applied to two cases of acquisitions in VersaCol...

  10. From BoP to ToP and vice versa daily practices in settings with limited resources to inspire designers

    NARCIS (Netherlands)

    Ibragimova, E.; van Boeijen, A.G.C.

    2014-01-01

    This paper reviews the methods and practices that reflect subconscious behaviours of people in daily lives. Cases, studied for this paper, show how practices of people living in poor settings, who are members of the base of the economic pyramid, contribute to designers, belonging to the top of the

  11. Laser corneal refractive surgery in the twenty-first century: a review of the impact of refractive surgery on high-order aberrations (and vice versa)

    Science.gov (United States)

    Arba-Mosquera, Samuel; Arbelaez, Maria C.; de Ortueta, Diego

    2010-07-01

    Here we review the situation of laser corneal refractive surgery in the twenty-first century. We pay special attention to the change in aberrations, covering the compensation of the loss of ablation efficiency at non-normal incidence, the effects of cyclotorsional errors, aspheric, wavefront optimized and aberration neutral concepts, and centration of refractive profiles. A review of the clinical outcomes is provided including myopic, hyperopic, and astigmatic, as well as wavefront customized or presbyopic outcomes.

  12. Transformations from an oblate spheroid to a plane and vice versa: The equations used in the cartographic projection program MAP2

    Science.gov (United States)

    Elliott, D. A.; Schwartz, A. A.

    1977-01-01

    The relationships between the coordinates of a point on the surface on an oblate spheroid and the coordinates of the projection of that point in several common map projections are discussed. Because several of the projections are conformal, the theory of conformally mapping an oblate spheroid to the plane is summarized. For each projection considered, the equations which map the spheroid to the plane and their inverses are given.

  13. Water-Borne Cues of a Non-Indigenous Seaweed Mediate Grazer-Deterrent Responses in Native Seaweeds, but Not Vice Versa

    Science.gov (United States)

    Yun, Hee Young; Engelen, Aschwin H.; Santos, Rui O.; Molis, Markus

    2012-01-01

    Plants optimise their resistance to herbivores by regulating deterrent responses on demand. Induction of anti-herbivory defences can occur directly in grazed plants or from emission of risk cues to the environment, which modifies interactions of adjacent plants with, for instance, their consumers. This study confirmed the induction of anti-herbivory responses by water-borne risk cues between adjoining con-specific seaweeds and firstly examined whether plant-plant signalling also exists among adjacent hetero-specific seaweeds. Furthermore, differential abilities and geographic variation in plant-plant signalling by a non-indigenous seaweed as well as native seaweeds were assessed. Twelve-day induction experiments using the non-indigenous seaweed Sargassum muticum were conducted in the laboratory in Portugal and Germany with one local con-familiar (Portugal: Cystoseira humilis, Germany: Halidrys siliquosa) and hetero-familiar native species (Portugal: Fucus spiralis, Germany: F. vesiculosus). All seaweeds were grazed by a local isopod species (Portugal: Stenosoma nadejda, Germany: Idotea baltica) and were positioned upstream of con- and hetero-specific seaweeds. Grazing-induced modification in seaweed traits were tested in three-day feeding assays between cue-exposed and cue-free ( = control) pieces of both fresh and reconstituted seaweeds. Both Fucus species reduced their palatability when positioned downstream of isopod-grazed con-specifics. Yet, the palatability of non-indigenous S. muticum remained constant in the presence of upstream grazed con-specifics and native hetero-specifics. In contrast, both con-familiar (but neither hetero-familiar) native species reduced palatability when located downstream of grazed S. muticum. Similar patterns of grazer-deterrent responses to water-borne cues were observed on both European shores, and were almost identical between assays using fresh and reconstituted seaweeds. Hence, seaweeds may use plant-plant signalling to optimise chemical resistance to consumers, though this ability appeared to be species-specific. Furthermore, this study suggests that native species may benefit more than a non-indigenous species from water-borne cue mediated reduction in consumption as only natives responded to signals emitted by hetero-specifics. PMID:22701715

  14. On the mutual effects of pain and emotion: facial pain expressions enhance pain perception and vice versa are perceived as more arousing when feeling pain.

    Science.gov (United States)

    Reicherts, Philipp; Gerdes, Antje B M; Pauli, Paul; Wieser, Matthias J

    2013-06-01

    Perception of emotional stimuli alters the perception of pain. Although facial expressions are powerful emotional cues - the expression of pain especially plays a crucial role for the experience and communication of pain - research on their influence on pain perception is scarce. In addition, the opposite effect of pain on the processing of emotion has been elucidated even less. To further scrutinize mutual influences of emotion and pain, 22 participants were administered painful and nonpainful thermal stimuli while watching dynamic facial expressions depicting joy, fear, pain, and a neutral expression. As a control condition of low visual complexity, a central fixation cross was presented. Participants rated the intensity of the thermal stimuli and evaluated valence and arousal of the facial expressions. In addition, facial electromyography was recorded as an index of emotion and pain perception. Results show that faces per se, compared to the low-level control condition, decreased pain, suggesting a general attention modulation of pain by complex (social) stimuli. The facial response to painful stimulation revealed a significant correlation with pain intensity ratings. Most important, painful thermal stimuli increased the arousal of simultaneously presented pain expressions, and in turn, pain expressions resulted in higher pain ratings compared to all other facial expressions. These findings demonstrate that the modulation of pain and emotion is bidirectional with pain faces being mostly prone to having mutual influences, and support the view of interconnections between pain and emotion. Furthermore, the special relevance of pain faces for the processing of pain was demonstrated. Copyright © 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  15. Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: data from the STURE registry showing that switching tumour necrosis factor α blockers can make sense

    Science.gov (United States)

    van Vollenhoven, R; Harju, A; Brannemark, S; Klareskog, L

    2003-01-01

    Objective: When one TNFα blocker (etanercept or infliximab) has failed, to determine whether it makes sense to treat patients with the other. Patients and methods: Since 1999 patients treated with etanercept or infliximab have been systematically followed up at our institution in the STURE database. We identified 31 patients who had received both agents. Results: Eighteen patients received etanercept first; discontinuation was mostly due to lack of efficacy. DAS28 values had improved only slightly with etanercept, with a mean (SEM) best DAS28 value of 4.8 (0.6). After switching to infliximab, the mean best DAS28 was 3.6 (0.6)—significantly better than the previous result (p<0.05). Similarly, the mean best ACR-N during etanercept treatment was 17.2 (6.65) and during subsequent infliximab treatment 40.4 (10.6) (p = 0.08). Thirteen patients received infliximab first; discontinuation was mainly due to adverse events. The best DAS28 value achieved during etanercept was 3.6 (0.4) compared with 4.1 (0.4) for infliximab (p<0.05), but the change in DAS28 was not different and ACR-N were similar for infliximab and etanercept in this group. Conclusion: For patients with insufficient efficacy from etanercept, treatment with infliximab provided better results, suggesting that a trial of infliximab is reasonable for such patients. For patients who discontinued infliximab owing to adverse events, treatment with etanercept gave at least similar clinical efficacy. Taken together, these data provide support for a trial of the reciprocal TNFα blocker in patients when one such agent has failed. PMID:14644858

  16. Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: data from the STURE registry showing that switching tumour necrosis factor alpha blockers can make sense.

    Science.gov (United States)

    van Vollenhoven, R; Harju, A; Brannemark, S; Klareskog, L

    2003-12-01

    When one TNFalpha blocker (etanercept or infliximab) has failed, to determine whether it makes sense to treat patients with the other. Since 1999 patients treated with etanercept or infliximab have been systematically followed up at our institution in the STURE database. We identified 31 patients who had received both agents. Eighteen patients received etanercept first; discontinuation was mostly due to lack of efficacy. DAS28 values had improved only slightly with etanercept, with a mean (SEM) best DAS28 value of 4.8 (0.6). After switching to infliximab, the mean best DAS28 was 3.6 (0.6)-significantly better than the previous result (p<0.05). Similarly, the mean best ACR-N during etanercept treatment was 17.2 (6.65) and during subsequent infliximab treatment 40.4 (10.6) (p = 0.08). Thirteen patients received infliximab first; discontinuation was mainly due to adverse events. The best DAS28 value achieved during etanercept was 3.6 (0.4) compared with 4.1 (0.4) for infliximab (p<0.05), but the change in DAS28 was not different and ACR-N were similar for infliximab and etanercept in this group. For patients with insufficient efficacy from etanercept, treatment with infliximab provided better results, suggesting that a trial of infliximab is reasonable for such patients. For patients who discontinued infliximab owing to adverse events, treatment with etanercept gave at least similar clinical efficacy. Taken together, these data provide support for a trial of the reciprocal TNFalpha blocker in patients when one such agent has failed.

  17. From community training to university training (and vice-versa: new sign language translator and interpreter profile in the brazilian context

    Directory of Open Access Journals (Sweden)

    Vanessa Regina de Oliveira Martins

    2015-10-01

    Full Text Available This paper aims to discuss the new profile of sign language translators/interpreters that is taking shape in Brazil since the implementation of policies stimulating the training of these professionals. We qualitatively analyzed answers to a semi-open questionary given by undergraduate students from a BA course in translation and interpretation in Brazilian sign language/Portuguese. Our results show that the ones to seek for this area are not, as it used to be, the ones who have some relation with the deaf community and/or need some kind of certification for their activity as a sign language interpreter. Actually, the students’ choice for the course in discussion had to do with their score in a unified profession selection system (SISU. This contrasts with the 1980, 1990, 2000 sign language interpreter’s profile. As Brazilian Sign Language has become more popular, people search for a university degree have started to see sign language translation/interpreting as an interesting option for their career. So, we discuss here the need to take into account the need to provide students who cannot sign with the necessary pedagogical means to learn the language, which will promote the accessibility of Brazilian deaf communities.

  18. From community training to university training (and vice-versa: new sign language translator and interpreter profile in the brazilian context

    Directory of Open Access Journals (Sweden)

    Vanessa Regina de Oliveira Martins

    2015-12-01

    Full Text Available This paper aims to discuss the new profile of sign language translators/interpreters that is taking shape in Brazil since the implementation of policies stimulating the training of these professionals. We qualitatively analyzed answers to a semi-open questionary given by undergraduate students from a BA course in translation and interpretation in Brazilian sign language/Portuguese. Our results show that the ones to seek for this area are not, as it used to be, the ones who have some relation with the deaf community and/or need some kind of certification for their activity as a sign language interpreter. Actually, the students’ choice for the course in discussion had to do with their score in a unified profession selection system (SISU. This contrasts with the 1980, 1990, 2000 sign language interpreter’s profile. As Brazilian Sign Language has become more popular, people search for a university degree have started to see sign language translation/interpreting as an interesting option for their career. So, we discuss here the need to take into account the need to provide students who cannot sign with the necessary pedagogical means to learn the language, which will promote the accessibility of Brazilian deaf communities.

  19. Water-borne cues of a non-indigenous seaweed mediate grazer-deterrent responses in native seaweeds, but not vice versa.

    Directory of Open Access Journals (Sweden)

    Hee Young Yun

    Full Text Available Plants optimise their resistance to herbivores by regulating deterrent responses on demand. Induction of anti-herbivory defences can occur directly in grazed plants or from emission of risk cues to the environment, which modifies interactions of adjacent plants with, for instance, their consumers. This study confirmed the induction of anti-herbivory responses by water-borne risk cues between adjoining con-specific seaweeds and firstly examined whether plant-plant signalling also exists among adjacent hetero-specific seaweeds. Furthermore, differential abilities and geographic variation in plant-plant signalling by a non-indigenous seaweed as well as native seaweeds were assessed. Twelve-day induction experiments using the non-indigenous seaweed Sargassum muticum were conducted in the laboratory in Portugal and Germany with one local con-familiar (Portugal: Cystoseira humilis, Germany: Halidrys siliquosa and hetero-familiar native species (Portugal: Fucus spiralis, Germany: F. vesiculosus. All seaweeds were grazed by a local isopod species (Portugal: Stenosoma nadejda, Germany: Idotea baltica and were positioned upstream of con- and hetero-specific seaweeds. Grazing-induced modification in seaweed traits were tested in three-day feeding assays between cue-exposed and cue-free ( = control pieces of both fresh and reconstituted seaweeds. Both Fucus species reduced their palatability when positioned downstream of isopod-grazed con-specifics. Yet, the palatability of non-indigenous S. muticum remained constant in the presence of upstream grazed con-specifics and native hetero-specifics. In contrast, both con-familiar (but neither hetero-familiar native species reduced palatability when located downstream of grazed S. muticum. Similar patterns of grazer-deterrent responses to water-borne cues were observed on both European shores, and were almost identical between assays using fresh and reconstituted seaweeds. Hence, seaweeds may use plant-plant signalling to optimise chemical resistance to consumers, though this ability appeared to be species-specific. Furthermore, this study suggests that native species may benefit more than a non-indigenous species from water-borne cue mediated reduction in consumption as only natives responded to signals emitted by hetero-specifics.

  20. Comunicação como midiatização: os meios em meio à tecnologia, sociedade, linguagem, e vice-versa

    Directory of Open Access Journals (Sweden)

    André Dornelles Pares

    2008-12-01

    Full Text Available É possível dizer que o campo de estudos da comunicação, já perfeitamente instituído, permanece discutindo a natureza do conhecimento da sua área. Também é razoável afirmar que um campo de conhecimento deve possuir especificidades que o garantam como campo autônomo de estudos. Partindo destas premissas, este artigo pretende discutir de forma introdutória uma demarcação possível para o estudo da comunicação. Como alternativa, supõe a comunicação como um processo de midiatização. Para isso, considera a posição fundamental dos meios, aqui entendidos como meios eletro-tecnológicos de comunicação de massa, que permitem o acesso plural e simultâneo às mensagens que produz. A partir daí, as relações entre linguagem e sociedade que possibilitam.

  1. Switch of Intravitreal Therapy for Macular Edema Secondary to Retinal Vein Occlusion from Anti-VEGF to Dexamethasone Implant and Vice Versa

    Directory of Open Access Journals (Sweden)

    Amelie Pielen

    2017-01-01

    Full Text Available Purpose. To evaluate the anatomical and functional outcome of intravitreal dexamethasone implant for macular edema secondary to central (C or branch (B retinal vein occlusion (RVO in patients with persistent macular edema (ME refractory to intravitreal antivascular endothelial growth factor (VEGF treatment compared to treatment naïve patients and to dexamethasone-refractory eyes switched to anti-VEGF. Methods. Retrospective, observational study including 30 eyes previously treated with anti-VEGF (8 CRVO, 22 BRVO, mean age 69 ± 10 yrs, compared to 11 treatment naïve eyes (6 CRVO, 5 BRVO, 73 ± 11 yrs and compared to dexamethasone nonresponders (2 CRVO, 4 BRVO, 69 ± 12. Outcome parameters were change in best-corrected visual acuity (BCVA and central foveal thickness (CFT measured by spectral-domain optical coherence tomography. Results. Mean BCVA improvement after switch to dexamethasone implant was 4 letters (p=0.08, and treatment naïve eyes gained 10 letters (p=0.66, while we noted no change in eyes after switch to anti-VEGF (p=0.74. Median CFT decrease was most pronounced in treatment naïve patients (−437 μm, p=0.002 compared to anti-VEGF refractory eyes (−170 μm, p=0.003 and dexamethasone-refractory eyes (−157, p=0.31. Conclusions. Dexamethasone significantly reduced ME secondary to RVO refractory to anti-VEGF. Functional gain was limited compared to treatment naïve eyes, probably due to worse BCVA and CFT at baseline in treatment naïve eyes.

  2. Aligning Existing USG RDD&D Funding Objectives with those of an Emerging Marine Based CCUS Industrial Sector...or...Vice Versa

    Science.gov (United States)

    Hayes, M.

    2016-12-01

    This article surveys USG laws, and other RDD&D funding mandate frameworks, which are related to biotic and/or abiotic Carbon Capture, Utilization, and Sequestration (CCUS) RDD&D. Prominent among the laws and other frameworks reviewed are: The Integrated Coastal and Ocean Observation Systems (ICOOS) Act of 2009, Federal Ocean Acidification Research and Monitoring (FOARAM) Act of 2009, Section 7406 of the Food, Conservation, and Energy (FCEA) Act of 2008 The National Oceanographic Partnership Act of 1997, and The National Ocean Plan This paper further explores the potential to significantly expand the USGs' related CCUS RDD&D funding potential through expanding the scope of the core CCUS technologies and/or markets definition(s) to include non-CCUS yet highly supportive marine based technologies and/or markets such as marine hyperloops and 'Blue' biochar/fertilizer respectively.

  3. Effect of a prior force-velocity test performed with legs on subsequent peak power output measured with arms or vice versa.

    Science.gov (United States)

    Bouhlel, Ezzedine; Chelly, Mohamed Souhaiel; Gmada, Nebil; Tabka, Zouhair; Shephard, Roy

    2010-04-01

    The aim of this study was to examine whether measurement of peak anaerobic power (Wpeak) by force-velocity test using the arms or the legs influenced the performance obtained when the opposite muscle group was tested. Ten trained male throwers (age: 20.6 +/- 2; stature: 1.82 +/- 0.06 m; and body mass: 85.5 +/- 17.2 kg) performed, on separate days, 2 Monark cycle-ergometer protocols comprising (a) arm cranking (A1) followed by a leg cycling (L2) force-velocity test (series A-L) and (b) a leg cycling (L1) followed by an arm cranking (A2) force-velocity test (series L-A). On each day, 8 minutes of seated rest separated the 2 force-velocity tests. Arterialized capillary blood was collected from the finger tips for blood lactate analysis at rest and at the end of each force-velocity test. Wpeak-A1 and Wpeak-A2 were similar (8.1 +/- 1.7 and 8.6 +/- 1.5 W.kg, respectively). Wpeak-L1 and Wpeak-L2 were 14.0 +/- 3 and 13.4 +/- 2.8 W.kg (NS). Blood [La] increased significantly after each force-velocity test (p < 0.001), but peak blood [La] did not differ significantly between L1 (6.6 +/- 1.2) and L2 (6.2 +/- 1.4 mmol.L) or between A1 (7.2 +/- 1.0) and A2 (7.4 +/- 1.6 mmol.L). In this population, force-velocity tests performed using the legs or the arms did not induce a significant decrease in force-velocity determinations of peak anaerobic power performed subsequently with the opposite muscle group. In strength-trained athletes, the force-velocity approach can thus be used to measure the peak power output of both the legs and the arms in a single laboratory session, without adversely affecting estimates of an athlete's performance.

  4. Tree species identity in high-latitude forests determines fire spread through fuel ladders from branches to soil and vice versa

    NARCIS (Netherlands)

    Blauw, Luke G.; van Logtestijn, Richard S.P.; Broekman, R.A.; Aerts, Rien; Cornelissen, J. Hans C.

    2017-01-01

    Peat fires in boreal and tundra regions can potentially cause a high CO2 release, because of their large soil carbon stocks. Under current and future climate warming the frequency and intensity of droughts are increasing and will cause the plant community and organic soil to become more susceptible

  5. ¿Qué aportan los estudios de felicidad al buen vivir, y viceversa? (What is the contribution of happiness studies in buen vivir, and vice versa?

    Directory of Open Access Journals (Sweden)

    Jorge Guardiola

    2011-07-01

    Full Text Available ResumenEn los últimos años, la ciencia se ha preocupado de estudiar la felicidad y sus causas. Sin embargo, en los estudios no se ha prestado demasiada atención a grupos de individuos que comparten una idea bastante personal sobre qué es el bienestar, que va más allá de la opinión occidental. El presente texto pretende analizar las posibles ventajas e inconvenientes, así como las limitaciones y aportaciones, que los estudios de felicidad pueden ocasionar en la comprensión del Buen Vivir de los pueblos indígenas latinoamericanos. También sacaremos conclusiones sobre qué puede aportar el Buen Vivir a los estudios de la felicidad.AbstractIn the last years, science has studied happiness and its causes. However, research has not given much attention to groups that share a particular view of happiness, that goes beyond the western idea. This paper aims to analyze the possible advantages and disadvantages, as well as limitations and contributions of happiness research in the comprehension of Buen Vivir of Latin American indigenous people. We also draw conclusions on the contribution of Buen Vivir in happiness studies.

  6. Do Sensitive Parents Foster Kind Children, or Vice Versa? Bidirectional Influences between Children's Prosocial Behavior and Parental Sensitivity

    Science.gov (United States)

    Newton, Emily K.; Laible, Deborah; Carlo, Gustavo; Steele, Joel S.; McGinley, Meredith

    2014-01-01

    Bidirectional theories of social development have been around for over 40 years (Bell, 1968), yet they have been applied primarily to the study of antisocial development. In the present study, the reciprocal relationship between parenting behavior and children's socially competent behaviors were examined. Using the National Institute of Child…

  7. Mechanoregulatory tumor-stroma crosstalk in pancreatic cancer: Measurements of the effects of extracellular matrix mechanics on tumor growth behavior, and vice-versa, to inform therapeutics

    Science.gov (United States)

    Celli, Jonathan; Jones, Dustin; El-Hamidi, Hamid; Cramer, Gwendolyn; Hanna, William; Caide, Andrew; Jafari, Seyedehrojin

    The rheological properties of the extracellular matrix (ECM) have been shown to play key roles in regulating tumor growth behavior through mechanotranduction pathways. The role of the mechanical microenvironment may be particularly important tumors of the pancreas, noted for an abundance of rigid fibrotic stroma, implicated in therapeutic resistance. At the same time, cancer cells and their stromal partners (e.g. tumor associated fibroblasts) continually alter the mechanical microenvironment in response to extracellular physical and biochemical cues as part of a two-way mechanoregulatory dialog. Here, we describe experimental studies using 3D pancreatic cell cultures with customized mechanical properties, combined with optical microrheology to provide insight into tumor-driven matrix remodeling. Quantitative microscopy provides measurements of phenotypic changes accompanying systematic variation of ECM composition in collagen and laminin-rich basement membrane admixtures, while analysis of the trajectories of passive tracer particles embedded in ECM report dynamic changes in heterogeneity, microstructure and local shear modulus accompanying both ECM stiffening (fibrosis) processes, and ECM degradation near invading cells. We gratefully acknowledge funding from the National Cancer Institute, R00CA155045 (PI: Celli).

  8. Importance of the Debye interaction in organic solutions: Henry's law constants for polar liquids in nonpolar solvents and vice versa

    Energy Technology Data Exchange (ETDEWEB)

    Rytting, J.H.; McHan, D.R.; Higuchi, T.; Grant, D.J.W.

    1986-08-01

    Henry's law constants have been determined for ..gamma..-butyrolactone (BL), ethyl acetate (EA), and 2-methyl-3-pentanol (MEP) in mixtures of iso-octane (ISO) and toluene (TOL), for BL, EA, TOL, and ISO in cinnamaldehyde (CIN) and for TOL and ISO in each other and in BL. From these data and published vapor pressures, the activity coefficients at infinite dilution and the standard molar Gibbs free energy of transfer, ..delta..G/sub 2/..pi.. of the solutes from dilute solution in ISO to dilute solution in each solvent medium have been calculated. The different behavior patterns of BL and EA are attributed to differences in their abilities to exist in different conformations possessing different dipole moments. For polar solutes, ..delta..G/sub 2//sup 0/ decreases with increasing polarizability of the solvent and with increasing dipole moment of the solute, suggesting increased contributions from dipole-induced dipole (Debye) interactions. The sigmoidal plot of ..delta..G/sub 2//sup 0/ against the change in pair potential energy calculated from the classical expressions suggests that ..delta..G/sub 2//sup 0/ seriously underestimates the strength of the Debye interactions in comparison with the London interactions.

  9. Attention deficit-hyperactivity disorder and early-onset bipolar disorder: two facets of one entity?

    Science.gov (United States)

    Zepf, Florian D

    2009-01-01

    Early-onset bipolar disorder (BD) and attention-deficit-hyperactivity disorder (ADHD) have recently been the subject of highly controversial debate, due to theories regarding underlying pathophysiological processes and a clinical overlap of symptoms. Epidemiological data, clinical aspects neuroimaging, neurochemical, and genetic studies suggest that there may be a possible relationship between biological factors and clinical characteristics in the development of symptoms. However, longitudinal data supporting the hypothesis of a diagnostic shift from BD to ADHD symptoms and vice versa are currently not available. These would be essential to enable further investigations into whether these two disorders possibly represent two different aspects of an underlying common psychopathophysiological entity.

  10. The Vices of Economists; The Virtues of the Bourgeoisie

    NARCIS (Netherlands)

    McCloskey, Deirdre N.

    1997-01-01

    The 'vices' are three bad habits into which economists have fallen over the past fifty years: bad statistics, bad theory, and bad applications of statistics and theory to public affairs. This book details the vices, tracing them to the influence of three giants of the 1940s and 1950s in economics,

  11. Executive Assistant to the Vice-President, Corporate Strategy and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary Under the direction of the Vice-President, Corporate Strategy and Communications, and reporting to the Senior Corporate Strategy and Communications Advisor, the Executive Assistant provides secretarial and administrative support to the OVP-CSC, and in particular to the Vice-President; performing a ...

  12. 11 CFR 103.4 - Vice Presidential candidate campaign depositories.

    Science.gov (United States)

    2010-01-01

    ... designated by the principal campaign committee of a political party's candidate for President shall be the campaign depository for that political party's candidate for the office of Vice President. ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Vice Presidential candidate campaign...

  13. 22 CFR 40.24 - Prostitution and commercialized vice.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Prostitution and commercialized vice. 40.24... Certain Crimes § 40.24 Prostitution and commercialized vice. (a) Activities within 10 years preceding visa... United States solely, principally, or incidentally to engage in prostitution, or has engaged in...

  14. 29 CFR 1601.4 - Vice Chairman's functions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Vice Chairman's functions. 1601.4 Section 1601.4 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURAL REGULATIONS Definitions § 1601.4 Vice Chairman's functions. The member of the Commission designated by the President to...

  15. Virus-Induced Chaperone-Enriched (VICE domains function as nuclear protein quality control centers during HSV-1 infection.

    Directory of Open Access Journals (Sweden)

    Christine M Livingston

    2009-10-01

    Full Text Available Virus-Induced Chaperone-Enriched (VICE domains form adjacent to nuclear viral replication compartments (RC during the early stages of HSV-1 infection. Between 2 and 3 hours post infection at a MOI of 10, host protein quality control machinery such as molecular chaperones (e.g. Hsc70, the 20S proteasome and ubiquitin are reorganized from a diffuse nuclear distribution pattern to sequestration in VICE domains. The observation that VICE domains contain putative misfolded proteins suggests that they may be similar to nuclear inclusion bodies that form under conditions in which the protein quality control machinery is overwhelmed by the presence of misfolded proteins. The detection of Hsc70 in VICE domains, but not in nuclear inclusion bodies, indicates that Hsc70 is specifically reorganized by HSV-1 infection. We hypothesize that HSV-1 infection induces the formation of nuclear protein quality control centers to remodel or degrade aberrant nuclear proteins that would otherwise interfere with productive infection. Detection of proteolytic activity in VICE domains suggests that substrates may be degraded by the 20S proteasome in VICE domains. FRAP analysis reveals that GFP-Hsc70 is dynamically associated with VICE domains, suggesting a role for Hsc70 in scanning the infected nucleus for misfolded proteins. During 42 degrees C heat shock, Hsc70 is redistributed from VICE domains into RC perhaps to remodel viral replication and regulatory proteins that have become insoluble in these compartments. The experiments presented in this paper suggest that VICE domains are nuclear protein quality control centers that are modified by HSV-1 to promote productive infection.

  16. Australian Higher Education Leaders in Times of Change: The Role of Pro Vice-Chancellor and Deputy Vice-Chancellor

    Science.gov (United States)

    Scott, Geoff; Bell, Sharon; Coates, Hamish; Grebennikov, Leonid

    2010-01-01

    This paper discusses responses provided by 31 Pro Vice-Chancellors (PVCs) and Deputy Vice-Chancellors (DVCs) who were part of a larger study of more than 500 higher education leaders in roles ranging from DVC to head of programme in 20 Australian universities. Using both quantitative and qualitative data the paper gives an insider's perspective on…

  17. Vices Among Commercial Chickens in Maiduguri, Borno State ...

    African Journals Online (AJOL)

    A survey was carried out to determine the presence of vices in commercial chickens in Maiduguri, Borno State, between Marchto July, 2005. Types, causes, and possible control measures were also investigated. Forty flocks were randomly selected and studied. These included institutional, government and private (small ...

  18. Vice's Vicious Virtues: The Supererogatory as Obligatory | Mills ...

    African Journals Online (AJOL)

    ... both in its enduring socio-economic structures and in its citizens' typical moral psychologies. Vice's conclusion is that shame is the moral emotion most appropriate for whites unable to free themselves from white privilege and live up to what she sees as the required standards of moral excellence. In response, I argue that ...

  19. Vice-Principalship: Their Responsibility Roles and Career Aspirations

    Science.gov (United States)

    Lee, John Chi-Kin; Kwan, Paula; Walker, Allan

    2009-01-01

    A discrepancy exists between the ideal and the actual roles played by vice-principals (VPs). This gap between roles influences the level of job satisfaction, which, in turn, affects their desire for a principalship. This study used a questionnaire survey of about 300 Hong Kong VPs to examine the core responsibility dimensions pertaining to their…

  20. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    ... to 2017-10-13. Destination(s):. Cairo, Egypt. Airfare: $4,512.88. Other. Transportation: $118.45. Accommodation: $494.52. Meals and. Incidentals: $300.00. Other: $114.20. Total: $5,540.05. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  1. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    BB

    2017-06-11 to 2017-06-14. Destination(s):. Montreal. Airfare: $0.00. Other. Transportation: $170.23. Accommodation: $793.75. Meals and. Incidentals: $103.67. Other: $0.00. Total: $1,067.65. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  2. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    2017-11-14 to 2017-11-15. Destination(s):. Calgary. Airfare: $468.90. Other. Transportation: $118.90. Accommodation: $223.42. Meals and. Incidentals: $116.64. Other: $46.00. Total: $973.86. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  3. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    BB

    Destination(s):. Guatemala/Honduras. Airfare: $3,069.59. Other. Transportation: $317.65. Accommodation: $2,136.60. Meals and. Incidentals: $532.40. Other: $0.00. Total: $6,056.24. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  4. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Date(s):. 2017-10-27. Destination(s):. Montreal. Airfare: $0.00. Other. Transportation: $315.96. Accommodation: $0.00. Meals and. Incidentals: $25.92. Other: $16.00. Total: $357.88. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  5. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Destination(s):. Kenya, Uganda and Tanzania. Airfare: $5,885.73. Other. Transportation: $70.60. Accommodation: $2,983.48. Meals and. Incidentals: $1,053.24. Other: $334.93. Total: $10,327.98. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  6. High density, multi-range analog output Versa Module Europa board for control system applications

    Science.gov (United States)

    Singh, Kundan; Das, Ajit Lal

    2014-01-01

    A new VMEDAC64, 12-bit 64 channel digital-to-analog converter, a Versa Module Europa (VME) module, features 64 analog voltage outputs with user selectable multiple ranges, has been developed for control system applications at Inter University Accelerator Centre. The FPGA (Field Programmable Gate Array) is the module's core, i.e., it implements the DAC control logic and complexity of VMEbus slave interface logic. The VMEbus slave interface and DAC control logic are completely designed and implemented on a single FPGA chip to achieve high density of 64 channels in a single width VME module and will reduce the module count in the control system applications, and hence will reduce the power consumption and cost of overall system. One of our early design goals was to develop the VME interface such that it can be easily integrated with the peripheral devices and satisfy the timing specifications of VME standard. The modular design of this module reduces the amount of time required to develop other custom modules for control system. The VME slave interface is written as a single component inside FPGA which will be used as a basic building block for any VMEbus interface project. The module offers multiple output voltage ranges depending upon the requirement. The output voltage range can be reduced or expanded by writing range selection bits in the control register. The module has programmable refresh rate and by default hold capacitors in the sample and hold circuit for each channel are charged periodically every 7.040 ms (i.e., update frequency 284 Hz). Each channel has software controlled output switch which disconnects analog output from the field. The modularity in the firmware design on FPGA makes the debugging very easy. On-board DC/DC converters are incorporated for isolated power supply for the analog section of the board.

  7. Book Review: Higher Education, Leadership and Women Vice Chancellors

    Directory of Open Access Journals (Sweden)

    Pamela L. Eddy

    2016-10-01

    Full Text Available The paucity of women leaders in higher education continues despite advancement by women in other fronts of the educational pipeline.  Today, more women are attending and graduating from college in the United States, but something occurs en route to the top-level leadership positions in these same college settings.  The portrait of college leaders continues to consist of White men, as it has since the initial founding of universities.  Paula Burkinshaw analyzes the situation of the missing women leaders in the United Kingdom, specifically in the position of Vice Chancellor.  Burkinshaw’s long career in leadership development in university settings initially provided her with an awareness of the underrepresentation of women in top leadership positions.  As she began her doctoral studies, she had an opportunity to ask “where are the women?”  Her book builds on her dissertation research, which involved one-on-one interviews with 18 women who were vice chancellors.

  8. Dosimetric validation of Monaco treatment planning system on an Elekta VersaHD linear accelerator.

    Science.gov (United States)

    Narayanasamy, Ganesh; Saenz, Daniel L; Defoor, Dewayne; Papanikolaou, Niko; Stathakis, Sotirios

    2017-11-01

    The purpose of this study is to perform dosimetric validation of Monaco treatment planning system version 5.1. The Elekta VersaHD linear accelerator with high dose rate flattening filter-free photon modes and electron energies was used in this study. The dosimetric output of the new Agility head combined with the FFF photon modes warranted this investigation into the dosimetric accuracy prior to clinical usage. A model of the VersaHD linac was created in Monaco TPS by Elekta using commissioned beam data including percent depth dose curves, beam profiles, and output factors. A variety of 3D conformal fields were created in Monaco TPS on a combined Plastic water/Styrofoam phantom and validated against measurements with a calibrated ion chamber. Some of the parameters varied including source to surface distance, field size, wedges, gantry angle, and depth for all photon and electron energies. In addition, a series of step and shoot IMRT, VMAT test plans, and patient plans on various anatomical sites were verified against measurements on a Delta 4 diode array. The agreement in point dose measurements was within 2% for all photon and electron energies in the homogeneous phantom and within 3% for photon energies in the heterogeneous phantom. The mean ± SD gamma passing rates of IMRT test fields yielded 93.8 ± 4.7% based on 2% dose difference and 2 mm distance-to-agreement criteria. Eight previously treated IMRT patient plans were replanned in Monaco TPS and five measurements on each yielded an average gamma passing rate of 95% with 6.7% confidence limit based on 3%, 3 mm gamma criteria. This investigation on dosimetric validation ensures accuracy of modeling VersaHD linac in Monaco TPS thereby improving patient safety. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  9. Developmental relations between sympathy, moral emotion attributions, moral reasoning, and social justice values from childhood to early adolescence.

    Science.gov (United States)

    Daniel, Ella; Dys, Sebastian P; Buchmann, Marlis; Malti, Tina

    2014-10-01

    This study examined the development of sympathy, moral emotion attributions (MEA), moral reasoning, and social justice values in a representative sample of Swiss children (N = 1273) at 6 years of age (Time 1), 9 years of age (Time 2), and 12 years of age (Time 3). Cross-lagged panel analyses revealed that sympathy predicted subsequent increases in MEA and moral reasoning, but not vice versa. In addition, sympathy and moral reasoning at 6 and 9 years of age were associated with social justice values at 12 years of age. The results point to increased integration of affect and cognition in children's morality from middle childhood to early adolescence, as well as to the role of moral development in the emergence of social justice values. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  10. A Conceptual Framework for Understanding the Working Relationship between School Principals and Vice-Principals

    Science.gov (United States)

    Wong, Ping-Man

    2009-01-01

    Vice-principals' role and their relationship with principals are of paramount importance in shaping the effectiveness of school management, particularly after the implementation of school-based management (SBM) worldwide. This paper reports primarily on prior studies on the vice-principalship and suggests a framework to help explain the different…

  11. Management and the Academic Vice President in the Christian, Liberal Arts College.

    Science.gov (United States)

    Oosting, Kenneth W.

    The role of nine academic vice presidents in managing Christian, liberal arts colleges was assessed, as part of research conducted at Christian or church-related liberal arts colleges that were identified as being well managed by one or more persons. Data collected on the academic vice presidents provided the following profile: the average age was…

  12. Developing Virtue and Rehabilitating Vice: Worries about Self-Cultivation and Self-Reform

    Science.gov (United States)

    Battaly, Heather

    2016-01-01

    Aristotelian virtue theorists have emphasized the role of the self in developing virtue and in rehabilitating vice. But this article argues that, as Aristotelians, we have placed too much emphasis on self-cultivation and self-reform. Self-cultivation is not required for developing virtue or vice. Nor will "sophia"-inspired self-reform…

  13. Lab work goes social, and vice versa: strategising public engagement processes : commentary on: "What happens in the lab does not stay in the lab: applying midstream modulation to enhance critical reflection in the laboratory".

    Science.gov (United States)

    Wynne, Brian

    2011-12-01

    Midstream modulation is a form of public engagement with science which benefits from strategic application of science and technology studies (STS) insights accumulated over nearly 20 years. These have been developed from STS researchers' involvement in practical engagement processes and research with scientists, science funders, policy and other public stakeholders. The strategic aim of this specific method, to develop what is termed second-order reflexivity amongst scientist-technologists, builds upon and advances earlier more general STS work. However this method is focused and structured so as to help generate such reflexivity-over the 'upstream' questions which have been identified in other STS research as important public issues for scientific research, development and innovation-amongst practising scientists-technologists in their specialist contexts (public or private, in principle). This is a different focus from virtually all such previous work, and offers novel opportunities for those key broader issues to be opened up. The further development of these promising results depends on some important conditions such as identifying and engaging research funders and other stakeholders like affected publics in similar exercises. Implementing these conditions could connect the productive impacts of midstream modulation with wider public engagement work, including with 'uninvited' public engagement with science. It would also generate broader institutional and political changes in the larger networks of institutional actors which constitute contemporary technoscientific innovation and governance processes. All of these various broader dimensions, far beyond the laboratory alone, need to be appropriately open, committed to democratic needs, and reflexive, for the aims of midstream modulation to be achieved, whilst allowing specialists to work as specialists.

  14. ’When Poverty Comes in at the Door, Love Flies Out the Window’: The Influence of Eurozone Reforms Upon the Social Dimension of the EU – and Vice Versa

    DEFF Research Database (Denmark)

    Neergaard, Ulla

    2016-01-01

    Th e economic crisis has brought the intriguing question of its eff ects on Social Europe sharply into focus. Th is contribution therefore goes to the heart of the puzzles and explores the mutual infl uence of Eurozone reforms and broader Union social policies with an additional focus on pointing...

  15. Terry Clements named Council of Educators of Landscape Architecture first vice-president

    OpenAIRE

    Chadwick, Heather Riley

    2010-01-01

    Terry L. Clements, associate professor of landscape architecture in the School of Architecture + Design, College of Architecture and Urban Studies, was elected to serve as first vice-president of the Council of Educators of Landscape Architecture (CELA).

  16. 27 October 2014 - L. Pistelli Vice Minister at Foreign Affairs and International Cooperation, Italian Republic

    CERN Multimedia

    Guillaume, Jeanneret

    2014-01-01

    Mr Lapo Pistelli Vice Minister at Foreign Affairs and International Cooperation, Member of the Italian Parliament (Chamber of Deputies), Italian Republic, signing the Guest Book with CERN Director-General R. Heuer ; Physics Department Head L. Mapelli also present

  17. 2017-2018 Hospitality Expense Reports for Stephen McGurk, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    Description: Lunch - Development research issues. Date: 2017-05-30. Attendees: 2 (IDRC 1). Location: Nairobi, Kenya. Total: $12.10. Comments: 2017-2018 Hospitality Expense Reports for. Stephen McGurk, Vice-President, Program and Partnership Branch.

  18. Scientific production of Vice Chancellors for Research in Peruvian universities with a medical school.

    Science.gov (United States)

    Herrera-Añazco, Percy; Valenzuela-Rodríguez, Germán; Pacheco-Mendoza, Josmel; Málaga, Germán

    2017-10-19

    To determine the scientific production of Research Vice-chancellors at Peruvian universities that have medical schools, as well as their academic degrees as an indirect way to evaluate their suitability for the position they hold. We searched all Peruvian universities that register medical schools. Of these, the scientific production of the universities registered in SCOPUS was identified in September of the 2016. The scientific production of the vice chancellors of investigation of these faculties of medicine was determined through the search of its scientific publications registered in SCOPUS and those reported in the National Registry of Researchers in Science and Technology. Academic degrees were obtained from the database of the National Superintendence of Higher University Education. The sample included 28 research vice chancellors. Only 4/28 had any publications. The average number of articles published by the vice chancellors of research was 1.71, the number of citations 23.1 on average and the H index 0.64. Besides, 22 Vice-chancellors of research had the degree of doctor, four had the degree of bachelor and two the degree of master. The scientific production of research vice chancellors is poor. The required academic grade requirement for the position is not met in all cases. It is likely that, having no research experience, his leadership in directing a university's research policies may be questioned.

  19. SU-E-T-74: Commissioning of the Elekta VersaHD Linear Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y; Ding, K; Hobbs, R; McNutt, T; Wang, K [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD (United States); Liang, X; Zhu, T [Department of Radiation Oncology, University of Pennsylvania, School of Medicine, Philadelphia, PA (United States)

    2014-06-01

    Purpose: To present the commissioning process of recently-released Elekta VersaHD linear accelerator, equipped with Agility 160-leaf multileaf collimator and flattening-filter free (FFF) photon modes. Methods: In addition to routine QA procedures, we adopted an EPID-based method to perform the table rotation and Winston-Lutz tests, and a novel multiradiation isocenter alignment check. The beam data acquired include photon percent-depth dose (PDD) of 6X, 6XFFF, 10X, 10XFFF, and 15X in the field size from 2×2 to 40×40cm{sup 2}, profiles, collimator and phantom scatter factors (Sc and Sp), wedge factor, electron (6, 9, 12, and 15MeV) PDD and profiles, cone and cutout factors, and virtual SSD. Validation measurements were carried out in water tank to evaluate the accuracy of beam modeling by the Pinnacle planning system. End-to-End test and IMRT QA were performed to validate the overall delivery accuracy. A theoretical model has also been used to extract the primary dose ratio and off-axis beam softening effects by fitting photon beam profile measurements. Results: The PDDs of FFF beams with field size 10×10cm{sup 2} at 10cm depth, 100cm SSD were intentionally adjusted within 1% of the non-FFF beams. The photon profiles of 30×30cm{sup 2} at 10cm depth between non-FFF and FFF beams are very different, OAR(10)=0.74 and 0.63, respectively, for 6XFFF and 10XFFF. The collimator and phantom scatter factors of FFF beam demonstrated smaller variation with field sizes. The EPID-based method demonstrated the maximum deviation between the table rotation axis and radiation isocenter is within 1mm, and the radiation isocenters are within 0.4mm relative to that of 6X. The validation measurement shows less than 2% deviation between the measurement and Pinnacle modeling for most of the test conditions. Conclusion: To the best of our knowledge, this is the first study reporting the Elekta VersaHD commissioning experience, which can be a valuable reference for the radiotherapy

  20. Aquinas on the Dangers of Natural Virtue and the Control of Natural Vice

    Directory of Open Access Journals (Sweden)

    Marie I. George

    2013-11-01

    Full Text Available I investigate Aquinas’s position that natural virtue can pose dangers to living a moral life, dangers that include natural virtue’s inflexibility to circumstance, the opposing vices it may breed if blindly followed, and its aptitude for deceiving people into thinking they are genuinely virtuous. I also consider whether Aquinas regards these problems as remediable given that he sees natural virtue and natural vice as instances of nature being determined to one. He maintains that we can overcome the moral pitfalls that natural virtue and natural vice pose, though perfect mastery is not possible without divine intervention, insofar as our bodily disposition is not directly subject to reason.

  1. Implementation of respiratory-gated VMAT on a Versa HD linear accelerator.

    Science.gov (United States)

    Snyder, Jeffrey E; Flynn, Ryan T; Hyer, Daniel E

    2017-09-01

    The accurate delivery of respiratory-gated volumetric modulated arc therapy (VMAT) treatment plans presents a challenge since the gantry rotation and collimator leaves must be repeatedly stopped and set into motion during each breathing cycle. In this study, we present the commissioning process for an Anzai gating system (AZ-733VI) on an Elekta Versa HD linear accelerator and make recommendations for successful clinical implementation. The commissioning tests include central axis dose consistency, profile consistency, gating beam-on/off delay, and comparison of gated versus nongated gamma pass rates for patient-specific quality assurance using four clinically commissioned photon energies: 6 MV, 6 FFF, 10 MV, and 10 FFF. The central axis dose constancy between gated and nongated deliveries was within 0.6% for all energies and the analysis of open field profiles for gated and nongated deliveries showed an agreement of 97.8% or greater when evaluated with a percent difference criteria of 1%. The measurement of the beam-on/off delay was done by evaluating images of a moving ball-bearing phantom triggered by the gating system and average beam-on delays of 0.22-0.29 s were observed. No measurable beam-off delay was present. Measurements of gated VMAT dose distributions resulted in decrements as high as 9% in the gamma passing rate as compared to nongated deliveries when evaluated against the planned dose distribution at 3%/3 mm. By decreasing the dose rate, which decreases the gantry speed during gated delivery, the gamma passing rates of gated and nongated treatments can be made equivalent. We present an empirically derived formula to limit the maximum dose rate during VMAT deliveries and show that by implementing a reduced dose rate, a gamma passing rate of greater than 95% (3%/3 mm) was obtained for all plan measurements. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of

  2. Irritable Bowel Syndrome and Stress-Related Psychiatric Co-morbidities: Focus on Early Life Stress.

    Science.gov (United States)

    O'Mahony, Siobhain M; Clarke, Gerard; Dinan, Timothy G; Cryan, John F

    2017-01-01

    Irritable bowel syndrome is a functional gastrointestinal disorder, with stress playing a major role in onset and exacerbation of symptoms such as abdominal pain and altered bowel movements. Stress-related disorders including anxiety and depression often precede the development of irritable bowel syndrome and vice versa. Stressor exposure during early life has the potential to increase an individual's susceptibility to both irritable bowel syndrome and psychiatric disease indicating that there may be a common origin for these disorders. Moreover, adverse early life events significantly impact upon many of the communication pathways within the brain-gut-microbiota axis, which allows bidirectional interaction between the central nervous system and the gastrointestinal tract. This axis is proposed to be perturbed in irritable bowel syndrome and studies now indicate that dysfunction of this axis is also seen in psychiatric disease. Here we review the co-morbidity of irritable bowel syndrome and psychiatric disease with their common origin in mind in relation to the impact of early life stress on the developing brain-gut-microbiota axis. We also discuss the therapeutic potential of targeting this axis in these diseases.

  3. Perspectives of UK Vice-Chancellors on Leading Universities in a Knowledge-Based Economy

    Science.gov (United States)

    Bosetti, Lynn; Walker, Keith

    2010-01-01

    This paper draws upon the experiences and perceptions of ten university vice-chancellors in the United Kingdom on the challenges they face in providing leadership and strategic direction for their institutions into the twenty-first century. The paper reveals the perceptions and spoken words of these leaders as they identify the key challenges…

  4. Dr Jung Hyun KIM Vice Minister for Education, Science and Technology MEST Republic of Korea

    CERN Multimedia

    Jean-Claude Gadmer

    2010-01-01

    He learnt about CERN's LHC computing grid project from Frédéric Hemmer, head of the information technology department. In addition, the vice-minister toured the ATLAS visitor centre, the CMS control centre, the ALICE experiment's exhibition and control room, and he met Korean scientists at CERN.

  5. 2017-2018 Hospitality Expense Reports for Stephen McGurk, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    Description: Dinner with development research partners. Date: 2017-05-16. Attendees: 6 (IDRC 3). Location: Yangon, Myanmar. Total: $68.52. Comments: 2017-2018 Hospitality Expense Reports for. Stephen McGurk, Vice-President, Program and Partnership Branch.

  6. The Academic Role of the Vice President for Health Sciences: Can a Walrus Become a Unicorn?

    Science.gov (United States)

    Pellegrino, Edmund D.

    1975-01-01

    The Vice President for Health Sciences is a term used for the chief administrative officer of a multi-unit health science component of a university. This essay reviews this job, and the transformation it has undergone in the past. (Editor/PG)

  7. Am I Their Cup of Tea? Vice-Principals' Perception of Suitability for Principalship

    Science.gov (United States)

    Kwan, Paula

    2013-01-01

    This paper attempts to address the principal shortage issue from the concept of fit perceived by job applicants. It links vice-principals' perception of suitability for principalship to their conception of how well they can match with the selection criteria set out by school hiring bodies. Based on evidence collected from aspiring principals in…

  8. Effects of Vice-Principals' Psychological Empowerment on Job Satisfaction and Burnout

    Science.gov (United States)

    Schermuly, Carsten C.; Schermuly, Rene A.; Meyer, Bertolt

    2011-01-01

    Purpose: This paper aims to investigate the relationship between psychological empowerment, job satisfaction, and burnout among vice-principals (VPs) in primary schools. Design/methodology/approach: A total of 103 VPs at 103 different primary schools in Germany were surveyed with a questionnaire that assessed the four dimensions of psychological…

  9. A Qualitative Analysis of the Leadership Style of a Vice-Chancellor in a Private University in Malaysia

    Directory of Open Access Journals (Sweden)

    Mabel Tan

    2015-03-01

    Full Text Available This study used Bolman and Deal’s framework to examine the leadership frames of a vice-chancellor in a private university in Malaysia. Qualitative methods comprised interviews with the vice-chancellor and six of his staff reporting directly to him, document analysis, and observations. Atlas.ti was used to code the leadership frames. Content analysis revealed that the vice-chancellor exhibited three frames, showing a multi-frame leadership style. It reflects the vice-chancellor implements an effective leadership style and a high level of cognitive ability, which is important for the organizational effectiveness.

  10. Comparison of the VersaTREK blood culture system against the Bactec9240 system in patients with suspected bloodstream infections

    Directory of Open Access Journals (Sweden)

    van Zyl Danie G

    2011-02-01

    Full Text Available Abstract Background To evaluate the VersaTREK (TREK Diagnostic Systems, Cleveland, Ohio blood culture system against the Bactec9240 (BD Microbiology, Cockeysville, MD, for the recovery of bloodstream pathogens. Methods Venous blood from patients with suspected bacterial sepsis was evenly distributed into bottles of each system. Positive signals were recorded and bottles processed onto standard media for organism recovery. False positive signals were regarded if no organisms were seen on Gram stain and no growth was observed. Results 177 bottles were available for analysis; the Bactec9240 system yielded 43 positive, 134 negative results and no false positive signals. The VersaTREK system had 58 positive signals with 14 being false positives. Conclusions In our setting with high background burden of immuno-compromised patients, the VersaTREK system compared favourably with the Bactec9240 in recovering blood stream aerobic and facultative anaerobic pathogens from patients with suspected bacterial sepsis. A concern is the high false positivity rate. Due to its versatility to accommodate small and large workloads as well as using smaller volumes of blood, this system may establish itself as a useful alternative for the recovery of bloodstream pathogens.

  11. Eighties' Film Noir: An Analysis of the Use of the "Double" in "Miami Vice's" Second and Third Seasons.

    Science.gov (United States)

    Matviko, John W.

    A comparison of the current television series "Miami Vice" with the "film noir" genre of American movies from the forties and fifties reveals many similar elements, such as visual style, mood, theme, and sensibility. "Miami Vice" is set in a large city whose art deco architecture provides an ironic contrast to noir's…

  12. Community College Vice Presidents for Institutional Advancement: Role Expectations, Fundraising Responsibilities, Professional Relationships, and Commitment to the Institution

    Science.gov (United States)

    Ciampa, Donna Lynn

    2009-01-01

    This study examined how the role expectations, responsibilities toward fundraising, and professional relationships by the vice president of institutional advancement influenced commitment to the institution. A qualitative analysis was conducted across the mid-Atlantic region by interviewing community college vice presidents of institutional…

  13. Vehicle Infrastructure Cash-Flow Estimation--VICE 2.0; Clean Cities, Energy Efficiency & Renewable Energy (EERE)

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, G.

    2015-04-02

    This presentation discusses the differences between the original Vehicle and Infrastructure Cash-Flow Evaluation (VICE) Model and the revamped version, VICE 2.0. The enhanced tool can now help assess projects to acquire vehicles and infrastructure, or to acquire vehicles only.

  14. Virtues, Vices, and Political Influence in the U.S. Senate.

    Science.gov (United States)

    ten Brinke, Leanne; Liu, Christopher C; Keltner, Dacher; Srivastava, Sameer B

    2016-01-01

    What qualities make a political leader more influential or less influential? Philosophers, political scientists, and psychologists have puzzled over this question, positing two opposing routes to political power--one driven by human virtues, such as courage and wisdom, and the other driven by vices, such as Machiavellianism and psychopathy. By coding nonverbal behaviors displayed in political speeches, we assessed the virtues and vices of 151 U.S. senators. We found that virtuous senators became more influential after they assumed leadership roles, whereas senators who displayed behaviors consistent with vices--particularly psychopathy--became no more influential or even less influential after they assumed leadership roles. Our results inform a long-standing debate about the role of morality and ethics in leadership and have important implications for electing effective government officials. Citizens would be wise to consider a candidate's virtue in casting their votes, which might increase the likelihood that elected officials will have genuine concern for their constituents and simultaneously promote cooperation and progress in government. © The Author(s) 2015.

  15. Vice presidential candidates in the American presidential elections: strategies for selection and effects

    Directory of Open Access Journals (Sweden)

    Marco Morini

    2015-07-01

    Full Text Available American vice presidential candidates are chosen for several reasons. Some of these rationales are easy to be recognized, while others belong to the cockles of the heart of the presidential candidates. Social scientists and journalists agree about the factors that are more essential: the vice presidential (VP nominee’s capacity of balancing the ideological and personal characteristics of the presidential candidate and the “native son” effect, namely the guarantee that the VP nominee would carry his/her own state. These strategies are often combined and they work at different electoral levels: the first one has usually a national or macro-regional significance while the second is crucial in the battleground states. This research is divided into two sections: the first one investigates the “balancing the ticket” strategy, offering an overview of about one century of presidential races. The second aims to verify the VP nominee’s effect in his/her home state. The results will confirm that there have been several running mates who have been selected in order to “balance the ticket” but also that the vice president nominee’s effect in the home states has been quite poor.

  16. Identifying early pathways of risk and resilience: The co-development of internalizing and externalizing symptoms and the role of harsh parenting

    Science.gov (United States)

    Wiggins, Jillian Lee; Mitchell, Colter; Hyde, Luke W.; Monk, Christopher S.

    2016-01-01

    Psychological disorders co-occur often in children, but little has been done to document the types of conjoint pathways internalizing and externalizing symptoms may take from the crucial early period of toddlerhood or how harsh parenting may overlap with early symptom co-development. To examine symptom co-development trajectories, we identified latent classes of individuals based on internalizing and externalizing symptoms across ages 3–9 and found three symptom co-development classes: normative symptoms (low), severe-decreasing symptoms (initially high but rapidly declining) and severe symptoms (high) trajectories. Next, joint models examined how parenting trajectories overlapped with internalizing and externalizing symptom trajectories. These trajectory classes demonstrated that, normatively, harsh parenting increased after toddlerhood, but the severe symptoms class was characterized by a higher level and steeper increase in harsh parenting and the severe-decreasing class by high, stable harsh parenting. Additionally, a transactional model examined the bi-directional relationships among internalizing and externalizing symptoms and harsh parenting as they may cascade over time in this early period. Harsh parenting uniquely contributed to externalizing symptoms, controlling for internalizing symptoms, but not vice versa. Also, internalizing symptoms appeared to be a mechanism by which externalizing symptoms increase. Results highlight the importance accounting for both internalizing and externalizing symptoms from an early age to understand risk for developing psychopathology and the role harsh parenting plays in influencing these trajectories. PMID:26439075

  17. BMI percentile-for-age overestimates adiposity in early compared with late maturing pubertal children.

    Science.gov (United States)

    Sørensen, Kaspar; Juul, Anders

    2015-08-01

    Early pubertal timing is consistently associated with increased BMI percentile-for-age in pubertal girls, while data in boys are more ambiguous. However, higher BMI percentile-for-age may be a result of the earlier puberty per se rather than vice versa. The aim was to evaluate markers of adiposity in relation to pubertal timing and reproductive hormone levels in healthy pubertal boys and girls. Population-based cross-sectional study (The Copenhagen Puberty Study). Eight-hundred and two healthy Caucasian children and adolescents (486 girls) aged 8.5-16.5 years participated. BMI and bioelectric impedance analyses (BIA) were used to estimate adiposity. Clinical pubertal markers (Tanner stages and testicular volume) were evaluated. LH, FSH, estradiol, testosterone, SHBG and IGF1 levels were determined by immunoassays. In all age groups, higher BMI (all 1 year age-groups, P ≤ 0.041) was found with early compared with late maturation, despite similar BIA-estimated body fat percentage (BIA-BF%). Neither BMI nor BIA-BF% differed for a given stage of maturation. BMI percentile-for-age and prevalence of overweight/obesity were higher in the early compared with late matured pubertal children (all P ≤ 0.038), despite similar BIA-BF%. Pubertal girls with BIA-BF >29% had significantly lower LH and FSH levels compared with normal-weight girls (P ≤ 0.041). Early maturational timing was not associated with higher adiposity for a given stage of puberty. Using BMI percentile-for-age overestimated the degree of adiposity in early pubertal compared with late pubertal children. © 2015 European Society of Endocrinology.

  18. Listening to Voices at the Educational Frontline: New Administrators’ Experiences of the Transition from Teacher to Vice-principal

    Directory of Open Access Journals (Sweden)

    Denise Armstrong

    2015-10-01

    Full Text Available This qualitative study examined the transition from teaching to administration through the voices four novice vice-principals. An integrative approach was used to capture the interaction between new vice-principals, their external contexts, and the resulting leadership outcomes. The data revealed that in spite of these new administrators’ intention to create better schools for all students, they encountered multiple factors that hindered their ability to achieve their leadership goals. Key obstacles included the ambiguous legal and institutional configuration of the vice-principalship, inadequate preparation for challenging front line managerial and disciplinary roles, and inappropriate transitional support. Through listening to new vice-principals voices and providing relevant preparation and coordinated supports, school districts and policy makers can improve this transition and address some of the leadership challenges facing schools.

  19. Developmental Links Between Children's Working Memory and their Social Relations with Teachers and Peers in the Early School Years.

    Science.gov (United States)

    de Wilde, Amber; Koot, Hans M; van Lier, Pol A C

    2016-01-01

    This study assessed the developmental links between children's working memory development and their relations with teachers and peers across 2 years of kindergarten and early elementary school. Kindergarten and first grade children, N = 1109, 50% boys, were followed across 2 school-years. Children were assessed across 3 waves, in the fall and spring of the first school-year (within school-year), and finally in the spring of the second school-year. Working memory was assessed using a visuo-spatial working memory task. The developmental links between working memory and child-reported teacher-child relationship quality (warmth and conflict) and peer-nominated likeability and friendedness were assessed using autoregressive cross-lagged models. Lower working memory scores were related to increases in teacher-child conflict and decreases in teacher-child warmth one school-year later, in addition to decreases in likeability by peers within the same school-year. Conversely, teacher-child conflict was negatively associated with the development of working memory across the studied period. Path estimates between working memory and social relational factors were similar for boys and girls. Findings show developmental links between working memory and social-relational factors and vice versa. These results suggest that children's working memory development can be fostered through pro-social relations with teachers in early elementary school children.

  20. Interference in early dual-task learning by predatory mites.

    Science.gov (United States)

    Christiansen, Inga C; Schausberger, Peter

    2017-11-01

    Animals are commonly exposed to multiple environmental stimuli, but whether, and under which circumstances, they can attend to multiple stimuli in multitask learning challenges is elusive. Here, we assessed whether simultaneously occurring chemosensory stimuli interfere with each other in a dual-task learning challenge. We exposed predatory mites Neoseiulus californicus early in life to either only conspecifics (kin) or simultaneously conspecifics (kin) and food (thrips or pollen), to determine whether presence of food interferes with social familiarization and, vice versa, whether presence of conspecifics interferes with learning the cues of thrips. We found that N. californicus can become familiar with kin early in life and use kin recognition later in life to avoid kin cannibalism. However, when the juvenile predators were challenged by multiple stimuli associated with two different learning tasks, that is, when they grew up with conspecifics in the presence of food, they were no longer capable of social familiarization. In contrast, the presence of conspecifics did not compromise the predators' ability to learn the cues of thrips. Memory of experience with thrips allowed shorter attack latencies on thrips and increased oviposition by adult N. californicus. Proximately, the stimuli for learning the features of thrips were apparently more salient than those for learning to recognize kin. We argue that, ultimately, learning the cues of thrips at the expense of impeded social familiarization pays off because of negligible cannibalism risk in the presence of abundant food. Our study suggests that stimulus-driven prioritization of learning tasks is in line with the predictions of selective and limited attention theories, and provides a key example of interference in dual-task learning by an arthropod.

  1. 5 CFR 315.602 - Appointment based on service in the Office of the President or Vice-President or on the White...

    Science.gov (United States)

    2010-01-01

    ... Office of the President or Vice-President or on the White House Staff. 315.602 Section 315.602... service in the Office of the President or Vice-President or on the White House Staff. (a) Agency authority... Office of the President or Vice-President or on the White House Staff, provided that the appointment is...

  2. Sugar in disguise or healthy indulgence: A cross-cultural comparision of the perceptions of dietary vice/virtue bundles

    Directory of Open Access Journals (Sweden)

    Jiraporn Napatsorn

    2016-07-01

    Full Text Available Consumers often choose virtue food to attain health goals and vice food to achieve indulgence goals. However, food and beverage companies have begun to nullify the vice and virtue categories by bundling vice and virtue ingredients into a single item (e.g. Yogurt with Oreo topping. This research contrasts how consumers from Asian and Western cultures evaluate such vice/virtue food bundles. Building on the perceptual processes and regulatory focus literatures, two cross-cultural experiments using participants in Thailand and the U.S. shows that Westerners prefer virtue-heavy bundles to vice-heavy bundles while Asians show similar preference across both types of bundle. Process measures revealed that Asians perceive greater fit between vice and virtue components in the bundles than Westerners and this perceived fit mediates the effect of culture on their food choice. Study 2 reveals the boundary condition. Specifically, when regulatory focus was manipulated, the effect of culture is no longer significant. The findings provide managerial implications for food and beverage companies as well as contributions to consumer behavior literature.

  3. SU-E-T-194: Commissioning of Monaco Treatment Planning System On An Elekta VersaHD Linear Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Narayanasamy, G; Bosse, C; Saenz, D; Cruz, W; Papanikolaou, N; Stathakis, S [University of Texas Health Science Center at San Antonio, TX (United States); Mavroidis, P [University of North Carolina, Chapel Hill, NC (United States)

    2015-06-15

    Purpose: The Monaco treatment planning system (TPS) uses a Monte-Carlo algorithm based dose computation engine to model the photon beams of a linear accelerator. The aim is to perform verification of Monaco TPS beam modeling of a Elekta VersaHD linac with 6MV, 6MV FFF, 10 MV, 10MV FFF, 18MV photon beams and 160 multileaf collimators (MLC) with a projected width of 5-mm at the isocenter. Methods: A series of dosimetric tests were performed to validate Monaco calculated beams including point dose measurement in water with and without heterogeneity and 2-dimensional dose distributions on a Delta4 bi-planar diode dosimeter array (Scandidos, Uppsala, Sweden). 3D conformal beams of different field sizes, source-to-surface distances, wedges, and gantry angles were delivered onto a phantom consisting of several plastic water and Styrofoam slabs. Point dose measurements were verified with a PTW 31013 Semiflex 0.3 cc ionization chamber (PTW, Freiburg, Germany). In addition, 8 step and shoot intensity modulated radiotherapy (IMRT) and volumetric modulated arc radiotherapy (VMAT) beams included in the Monaco TPS commissioning suite were verified against measurements on Delta4 to test and fine tune parameters in the beam model. IMRT verification was computed using gamma analysis with dose difference and distance-to-agreement criteria of 3%/3mm with a dose threshold of 10%. Results: Point dose measurements agreed within 2% in the homogeneous phantom and within 3% in the heterogeneous phantom for all photon energies. IMRT beams yielded a passing percentage of 99.1±1.1% in the gamma analysis which is well above the institutional passing threshold of 90%. Conclusion: Monaco TPS commissioning was successfully performed for all the photon energies on the Elekta VersaHD linac prior to clinical usage.

  4. Flattening filter free beams from TrueBeam and Versa HD units: Evaluation of the parameters for quality assurance.

    Science.gov (United States)

    Fogliata, Antonella; Fleckenstein, Jens; Schneider, Frank; Pachoud, Marc; Ghandour, Sarah; Krauss, Harald; Reggiori, Giacomo; Stravato, Antonella; Lohr, Frank; Scorsetti, Marta; Cozzi, Luca

    2016-01-01

    Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed based on a renormalization factor for FFF profiles. The present study aims to assess the dosimetric differences between FFF beams generated by linear accelerators from different vendors, and to provide renormalization and parameter data of the two kinds of units. Dosimetric data from two Varian TrueBeam and two Elekta Versa HD linear accelerators, all with 6 and 10 MV nominal accelerating potentials, FF and FFF modes have been collected. Renormalization factors and related fit parameters according to Fogliata et al. ["Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy," Med. Phys. 39, 6455-6464 (2012)] have been evaluated for FFF beams of both units and energies. Unflatness and slope parameters from profile curves were evaluated. Dosimetric differences in terms of beam penetration and near-the-surface dose were also assessed. FFF profile parameters have been updated; renormalization factors and unflatness from the Varian units are consistent with the published data. Elekta FFF beam qualities, different from the Varian generated beams, tend to express similar behaviour as the FF beam of the corresponding nominal energy. TPR20,10 for 6 and 10 MV FF and FFF TrueBeam beams are 0.665, 0.629 (6 MV) and 0.738, 0.703 (10 MV). The same figures for Versa HD units are 0.684, 0.678 (6 MV) and 0.734, 0.721 (10 MV). Renormalization factor and unflatness parameters evaluated from Varian and Elekta FFF beams are provided, in particular renormalization factors table and fit parameters.

  5. Impact of Vice President Cheney on public interest in left ventricular assist devices and heart transplantation.

    Science.gov (United States)

    Pandey, Ambarish; Abdullah, Kazeen; Drazner, Mark H

    2014-05-01

    Although celebrity illnesses attract a significant amount of media attention in the United States, there are few studies that have looked at how celebrity health conditions impact the awareness of the illness in the general population. Recently, Vice President Cheney underwent left ventricular assist device (LVAD) implantation and subsequently a cardiac transplant. The aim of this study was to determine whether there was evidence of increased interest in these 2 procedures as assessed by social media. We determined the relative frequency of Google searches for LVAD and heart transplantation from 2004 to 2013 using Google trends. We also counted the number of YouTube videos and Twitter messages posted monthly concerning LVADs over a 7-year time frame. There was a significant spike in the Google search interest for LVAD and heart transplantation in the month when Vice President Cheney underwent the respective procedure. Similarly, there was a large increase in YouTube videos and Twitter messages concerning LVADs shortly after he was implanted. In total, these data support the concept that a public figure's illness can significantly influence the public's interest in that condition and its associated therapies. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. An attempt to appoint a Swedish vice consul to Bucharest (1834-1835

    Directory of Open Access Journals (Sweden)

    Veniamin Ciobanu

    2012-08-01

    Full Text Available The economic development of Sweden at the end of the second decade of the nineteenth century accentuated the interest of the Swedish ruling circles to valorize the new economic potential. A series of measures, as the dissolution of the terrestrial customs between Sweden and Norway in 1825, or the abolition of the protectionist policy in imports, opened the way for the conclusion of certain commercial treaties with other states, such as that with Great Britain in 1826 or with the Ottoman Empire in 1827. Consequently, the commercial fleet, especially the Norwegian one, registered a substantial development. In this context, the Swedish diplomacy continued to pay close attention to Eastern Europe where favorable conditions for the extension of the foreign trade of Sweden and Norway could be found. This space, where the Romanian Principalities were located, had a geostrategic position and economic potential that had to be valorized. In order to achieve this goal, Sweden appointed consuls and vice consuls in the Romanian Principalities. The attempt to appoint a vice consul to Bucharest between 1834 and 1835 circumscribes this effort. The information regarding these demarches came from Swedish diplomatic reports, held in the funds of the National Archives of Sweden (Sveriges Riksarkivet, from Stockholm and offers, among many other details which may serve to broaden the horizon of the research regarding the history of Romanian-Swedish relations in the first half of the nineteenth century, an image of the Lutheran community from the capital of Wallachia.

  7. [CARDIORENAL SYNDROME: CLINICAL FEATURES, EARLY DIAGNOSIS AND TREATMENT AT FAMILY MEDICINE].

    Science.gov (United States)

    Marković, B Bergman

    2016-12-01

    The interdependent damage to the heart and kidney organ systems is defined as cardiorenal syndrome, a complex pathophysiological disorder of the heart and kidney in which acute or chronic dysfunction of one organ can lead to acute or chronic damage to the other. Identification and early diagnosis of some subtypes of cardiorenal syndrome very often begin at family physician office, however, the use of simple and reliable diagnostic procedures such as MICE score using ECG and biomarkers has not been implemented yet. The clinical picture, diagnosis and treatment vary according to the 5 cardiorenal syndrome subtypes, as described herein. Rational diagnosis of heart failure at family medicine office should include biomarkers (BNP and NT-pro BNP) before performing ultrasound of the heart, while for kidneys creatinine and estimated glomerular filtration rate are still in use, but not cysteine C and NGAL. Diagnostic procedure for suspected heart failure at family medicine office should include kidney function estimate and vice versa. Access to treatment of cardiorenal syndrome differs depending on the specialty to which the patient is referred first, i.e. consultant examination, cardiologist or nephrologist. A multidisciplinary approach to treatment of cardiorenal syndrome is still lacking.

  8. Is parent-child bed-sharing a risk for wheezing and asthma in early childhood?

    Science.gov (United States)

    Luijk, Maartje P C M; Sonnenschein-van der Voort, Agnes M M; Mileva-Seitz, Viara R; Jansen, Pauline W; Verhulst, Frank C; Hofman, Albert; Jaddoe, Vincent W V; de Jongste, Johan C; van IJzendoorn, Marinus H; Duijts, Liesbeth; Tiemeier, Henning

    2015-03-01

    Household crowding can place young children at risk for respiratory infections which subsequently provoke asthma symptoms. However, crowding might also protect against asthma, in accordance with the hygiene hypothesis. We tested if parent-infant bed-sharing, an important dimension of household crowding, increases or decreases the risk for asthma. In a population-based prospective cohort (N = 6160) we assessed bed-sharing at 2 and 24 months; wheezing between 1 and 6 years of age; and asthma at 6 years of age. Generalised estimating equation models were used to assess repeated measures of wheezing and asthma. We found no association between bed-sharing in early infancy and wheezing or diagnosis of asthma. By contrast, we found a positive association between bed-sharing in toddlerhood and both wheezing (OR 1.42, 95% CI 1.15-1.74) and asthma (OR 1.57, 95% CI 1.03-2.38). Wheezing was not associated with bed-sharing when using cross-lagged modelling. This study suggests that bed-sharing in toddlerhood is associated with an increased risk of asthma at later ages, and not vice versa. Further studies are needed to explore the underlying causal mechanisms. Copyright ©ERS 2015.

  9. Being stuck in a vice: The process of coping with severe depression in late life.

    Science.gov (United States)

    Bjørkløf, Guro Hanevold; Kirkevold, Marit; Engedal, Knut; Selbæk, Geir; Helvik, Anne-Sofie

    2015-01-01

    Articles describing older persons' experiences of coping with severe depression are, to our knowledge, lacking. This article is methodologically grounded in phenomenological hermeneutics, inspired by Paul Ricoeur, and applies a descriptive design with in-depth interviews for producing the data. We included 18 older persons, 13 women and 5 men, with a mean age of 77.9 years, depressed to a severe or moderate degree, 1-2 weeks after admission to a hospital for treatment of depression. We found the metaphor "being in a vice" to capture the essence of meaning from the participants' stories, and can be understood as being stuck in an immensely painful existence entirely dominated by depression in late life. This is the first article where coping in older men and women experiencing the most severe phase of depression is explored.

  10. Career development resource: educational leadership in a department of surgery: vice chairs for education.

    Science.gov (United States)

    Sanfey, Hilary; Boehler, Margaret; DaRosa, Debra; Dunnington, Gary L

    2012-07-01

    The growing appreciation of the need to adopt an evidence-based approach to teaching and assessment has led to a demand for faculty who are well versed in best practices in education. Surgeons with interest and expertise in instruction, curriculum development, educational research, and evaluation can have an important impact on the educational mission of a department of surgery. The increased fervor for accountability in education together with the challenges imposed by accreditation agencies and hospitals has made educational leadership responsibilities more time consuming and complex. In response to this, an increasing number of department chairs created Vice Chair for Education positions to support clerkship and program directors and ensure the department's education mission statement is fulfilled. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Flattening filter free beams from TrueBeam and Versa HD units: Evaluation of the parameters for quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    Fogliata, Antonella, E-mail: antonella.fogliata@humanitas.it; Reggiori, Giacomo; Stravato, Antonella; Scorsetti, Marta; Cozzi, Luca [Radiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan-Rozzano I-20098 (Italy); Fleckenstein, Jens; Schneider, Frank; Lohr, Frank [Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Mannheim D-68167 (Germany); Pachoud, Marc; Ghandour, Sarah [Radiation Oncology Department, Hôpital Riviera Chablais, Vevey CH-1800 (Switzerland); Krauss, Harald [Radio-Oncology Department, Kaiser Franz Josef Spital, Vienna A-1100 (Austria)

    2016-01-15

    Purpose: Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed based on a renormalization factor for FFF profiles. The present study aims to assess the dosimetric differences between FFF beams generated by linear accelerators from different vendors, and to provide renormalization and parameter data of the two kinds of units. Methods: Dosimetric data from two Varian TrueBeam and two Elekta Versa HD linear accelerators, all with 6 and 10 MV nominal accelerating potentials, FF and FFF modes have been collected. Renormalization factors and related fit parameters according to Fogliata et al. [“Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy,” Med. Phys. 39, 6455–6464 (2012)] have been evaluated for FFF beams of both units and energies. Unflatness and slope parameters from profile curves were evaluated. Dosimetric differences in terms of beam penetration and near-the-surface dose were also assessed. Results: FFF profile parameters have been updated; renormalization factors and unflatness from the Varian units are consistent with the published data. Elekta FFF beam qualities, different from the Varian generated beams, tend to express similar behaviour as the FF beam of the corresponding nominal energy. TPR{sub 20,10} for 6 and 10 MV FF and FFF TrueBeam beams are 0.665, 0.629 (6 MV) and 0.738, 0.703 (10 MV). The same figures for Versa HD units are 0.684, 0.678 (6 MV) and 0.734, 0.721 (10 MV). Conclusions: Renormalization factor and unflatness parameters evaluated from Varian and Elekta FFF beams are provided, in particular renormalization factors table and fit parameters.

  12. DEMOCRACIES VIRTUES AND VICES VIRTUDES E VÍCIUS DA DEMOCRACIA

    Directory of Open Access Journals (Sweden)

    Helena Esser dos Reis

    2008-04-01

    Full Text Available Democracy can be regarded, following Alexis de Tocquevilles
    thoughts, from two complementary standpoints: the equality standpoint – where equality is understood as a social condition; and the liberty standpoint – understood as a political condition. However, he observes, democracy is not a priori what it should be, denunciating, in this way, the imbalance between equality and liberty, the greater the imbalance as poor are the public virtues. We intend to enroll in a debate involving ethics and politics, by considering vices and virtues inherent to democracy, analyzing Tocqueville´s ideas. We start examining the causes of vice and the possibility of virtue, as Tocqueville sees them, in order to, next, attack the relationship of ethics and politics.A democracia pode ser compreendida, segundo Aléxis de Tocqueville, a partir de duas idéias complementares: a condição social de igualdade e a condição política de liberdade. Entretanto, observa, a democracia não é a priori o que deveria ser, denunciando, deste modo, a existência de um descompasso entre a igualdade e a liberdade que cresce na mesma medida em que esmorecem as virtudes públicas. Visando contribuir com a discussão acerca das relações entre ética e política, pretendo examinar virtudes e vícios inerentes ao Estado democrático, a partir da análise das idéias de Tocqueville. Meu interesse será, em primeiro lugar, compreender
    as causas dos vícios e a possibilidade das virtudes nas democracias, para, então, discutir a relação entre a ética e a política.

  13. The Early Development of the Open University: Report of the Vice-Chancellor January 1969-December 1970.

    Science.gov (United States)

    Open Univ., Walton, Bletchley, Bucks (England).

    This report concerns the extablishment and development of the British Open University. Contents include the descriptions of: the development of the institution; staffing the open university; development of the Milton Keynes Campus; undergraduate course development; regional organization; demand for open university courses; development, production,…

  14. Controllably Designed "Vice-Electrode" Interlayers Harvesting High Performance Lithium Sulfur Batteries.

    Science.gov (United States)

    Hao, Youchen; Xiong, Dongbin; Liu, Wen; Fan, Linlin; Li, Dejun; Li, Xifei

    2017-11-22

    An interlayer has been regarded as a promising mediator to prolong the life span of lithium sulfur batteries because its excellent absorbability to soluble polysulfide efficiently hinders the shuttle effect. Herein, we designed various interlayers and understand the working mechanism of an interlayer for lithium sulfur batteries in detail. It was found that the electrochemical performance of a S electrode for an interlayer located in cathode side is superior to the pristine one without interlayers. Surprisingly, the performance of the S electrode for an interlayer located in anode side is poorer than that of pristine one. For comparison, glass fibers were also studied as a nonconductive interlayer for lithium sulfur batteries. Unlike the two interlayers above, these nonconductive interlayer did displays significant capacity fading because polysulfides were adsorbed onto insulated interlayer. Thus, the nonconductive interlayer function as a "dead zone" upon cycling. Based on our findings, it was for the first time proposed that a controllably optimized interlayer, with electrical conductivity as well as the absorbability of polysulfides, may function as a "vice-electrode" of the anode or cathode upon cycling. Therefore, the cathodic conductive interlayer can enhance lithium sulfur battery performance, and the anodic conductive interlayer may be helpful for the rational design of 3D networks for the protection of lithium metal.

  15. The Effect of Role Ambiguity and Role Conflict on Performance of Vice Principals: The Mediating Role of Burnout

    Science.gov (United States)

    Celik, Kazim

    2013-01-01

    Problem Statement: Role ambiguity and role conflict are considered issues that affect performance and lead to burnout. While numerous studies have analyzed role ambiguity or role conflict in relation to burnout or performance, few studies have studied all of these issues together. Since vice principals are expected to carry out a variety of…

  16. Selection Criteria, Skill Sets and Competencies: What Is Their Role in the Appointment of Vice-Chancellors in Australian Universities?

    Science.gov (United States)

    O'Meara, Bernard; Petzall, Stanley

    2009-01-01

    Purpose: The research presented here attempts to identify and analyse the reported selection criteria used in the appointment of Australian vice-chancellors (VCs) and to contrast this with the selection criteria actually used. Design/methodology/approach: Contemporary research into the nature, role and purpose of section criteria in appointment…

  17. The Lived Experiences of Vice Presidents for Student Affairs: A Study Exploring How Social Identity Impacts Leadership Approach

    Science.gov (United States)

    Jones, David E.

    2016-01-01

    This study aimed to both draw awareness and increase understanding of how lived experiences across race, gender and sexual orientation social identities impact the leadership approach of Vice Presidents for Student Affairs. As the student demographic becomes increasingly more diverse on college and university campuses, higher education leaders…

  18. Day-night dip and early-morning surge in blood pressure in hypertension: prognostic implications.

    Science.gov (United States)

    Verdecchia, Paolo; Angeli, Fabio; Mazzotta, Giovanni; Garofoli, Marta; Ramundo, Elisa; Gentile, Giorgio; Ambrosio, Giuseppe; Reboldi, Gianpaolo

    2012-07-01

    We investigated the relationship between the day-night blood pressure (BP) dip and the early morning BP surge in an cohort of 3012 initially untreated subjects with essential hypertension. The day-night reduction in systolic BP showed a direct association with the sleep trough (r = 0.564; P surge. Over a mean follow-up period of 8.44 years, 268 subjects developed a major cardiovascular event (composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, and heart failure requiring hospitalization) and 220 subjects died. In a Cox model, after adjustment for predictive covariates, including age, sex, diabetes mellitus, cigarette smoking, total cholesterol, left ventricular hypertrophy on ECG, estimated glomerular filtration rate, and average 24-hour systolic BP, a blunted sleep trough (≤ 19.5 mm Hg; quartile 1) and preawakening (≤ 9.5 mm Hg; quartile 1) BP surge was associated with an excess risk of events (hazard ratio, 1.66 [95% CI, 1.14-2.42]; P = 0.009; hazard ratio, 1.71 [95% CI, 1.12-2.71]; P = 0.013). After adjustment for the same covariates, neither the dipping pattern nor the measures of early morning BP surge were independent predictors of mortality. In conclusion, in initially untreated subjects with hypertension, a blunted day-night BP dip was associated with a blunted morning BP surge and vice versa. In these subjects, a blunted morning BP surge was an independent predictor of cardiovascular events, whereas an excessive BP surge did not portend an increased risk of events.

  19. Rapid Changes in Cortical and Subcortical Brain Regions after Early Bilateral Enucleation in the Mouse.

    Directory of Open Access Journals (Sweden)

    Olga O Kozanian

    Full Text Available Functional sensory and motor areas in the developing mammalian neocortex are formed through a complex interaction of cortically intrinsic mechanisms, such as gene expression, and cortically extrinsic mechanisms such as those mediated by thalamic input from the senses. Both intrinsic and extrinsic mechanisms are believed to be involved in cortical patterning and the establishment of areal boundaries in early development; however, the nature of the interaction between intrinsic and extrinsic processes is not well understood. In a previous study, we used a perinatal bilateral enucleation mouse model to test some aspects of this interaction by reweighting sensory input to the developing cortex. Visual deprivation at birth resulted in a shift of intraneocortical connections (INCs that aligned with ectopic ephrin A5 expression in the same location ten days later at postnatal day (P 10. A prevailing question remained: Does visual deprivation first induce a change in gene expression, followed by a shift in INCs, or vice versa? In the present study, we address this question by investigating the neuroanatomy and patterns of gene expression in post-natal day (P 1 and 4 mice following bilateral enucleation at birth. Our results demonstrate a rapid reduction in dorsal lateral geniculate nucleus (dLGN size and ephrin A5 gene expression 24-hours post-enucleation, with more profound effects apparent at P4. The reduced nuclear size and diminished gene expression mirrors subtle changes in ephrin A5 expression evident in P1 and P4 enucleated neocortex, 11 and 8 days prior to natural eye opening, respectively. Somatosensory and visual INCs were indistinguishable between P1 and P4 mice bilaterally enucleated at birth, indicating that perinatal bilateral enucleation initiates a rapid change in gene expression (within one day followed by an alteration of sensory INCs later on (second postnatal week. With these results, we gain a deeper understanding of how gene

  20. Linking Executive Function and Peer Problems from Early Childhood Through Middle Adolescence.

    Science.gov (United States)

    Holmes, Christopher J; Kim-Spoon, Jungmeen; Deater-Deckard, Kirby

    2016-01-01

    Peer interactions and executive function play central roles in the development of healthy children, as peer problems have been indicative of lower cognitive competencies such as self-regulatory behavior and poor executive function has been indicative of problem behaviors and social dysfunction. However, few studies have focused on the relation between peer interactions and executive function and the underlying mechanisms that may create this link. Using a national sample (n = 1164, 48.6% female) from the Study of Early Child Care and Youth Development (SECCYD), we analyzed executive function and peer problems (including victimization and rejection) across three waves within each domain (executive function or peer problems), beginning in early childhood and ending in middle adolescence. Executive function was measured as a multi-method, multi-informant composite including reports from parents on the Children's Behavior Questionnaire and Child Behavior Checklist and child's performance on behavioral tasks including the Continuous Performance Task, Woodcock-Johnson, Tower of Hanoi, Operation Span Task, Stroop, and Tower of London. Peer problems were measured as a multi-informant composite including self, teacher, and afterschool caregiver reports on multiple peer-relationship scales. Using a cross-lagged design, our Structural Equation Modeling findings suggested that experiencing peer problems contributed to lower executive function later in childhood and better executive function reduced the likelihood of experiencing peer problems later in childhood and middle adolescence, although these relations weakened as a child moves into adolescence. The results highlight that peer relationships are involved in the development of strengths and deficits in executive function and vice versa.

  1. Child regulative temperament as a mediator of parenting in the development of depressive symptoms: a longitudinal study from early childhood to preadolescence.

    Science.gov (United States)

    Pitzer, Martina; Esser, Guenter; Schmidt, Martin H; Hohm, Erika; Banaschewski, Tobias; Laucht, Manfred

    2017-05-01

    Child temperament as well as parenting behaviors have been linked to adolescent depression. Beyond their main effects, the interplay between these factors is of interest. For example, in an interactive model, a differential susceptibility of temperamental variants to parenting has been suggested. However, so far, the differential susceptibility hypothesis has mostly been studied with a focus on externalizing disorders. On the other hand, parenting may shape the child's temperament and vice versa in a transactional process. In a prospective, longitudinal at-risk sample (163 boys, 176 girls), we assessed emotional (easy-difficult) and regulative (self-control) temperament at ages 4.5, and 8 years, respectively, as well as parenting quality at age 4.5 years using the HOME inventory. Hierarchical linear regression analysis was used to investigate the prediction of depressive symptoms at age 11, measured by the Child Depression Inventory, including interaction terms between the temperament variable and parenting. We additionally tested whether parenting was mediated by child temperament. As previously reported, both self-control and parenting were longitudinally associated with preadolescent depressive symptoms. There were no interactive effects between temperament and parenting. However, the effects of parenting were partly mediated by self-control. Our data do not support a differential susceptibility of temperamental variants in the development of preadolescent depression. However, our results are in line with the assumption that parenting may shape young children's temperament, with positive parenting in the early childhood fostering the development of regulative temperament.

  2. A Study on the Optimization of Surfactants in the Main and Vice Slug in Weak Base ASP Flooding

    Directory of Open Access Journals (Sweden)

    Bin Huang

    2017-03-01

    Full Text Available In ASP (Alkali-Surfactant-Polymer flooding processes, surfactants help to enhance oil recovery by lowering the interfacial tension between the oil and water. However, due to the high cost of surfactants and the stability of the emulsion that varies with surfactant concentration, it is necessary to optimize the surfactant concentration in ASP flooding. In this study, we combined numerical simulation and physical experimental research to solve this problem. In order to screen for the optimal surfactant concentration in the main and vice slugs, CMG (Computer Measurement Group numerical simulation software was used to change the surfactant concentration in the injected compound system and the oil recovery factor and the recovery percent of reserves were compared. The physical experiments were also carried out with different surfactant concentrations and the results verified the simulation results. It shows that the recovery factor increases with the surfactant concentration. The optimal surfactant concentration in the main and vice slug are 0.3% and 0.15%, respectively. As for improving the recovery factor, it is more efficient to increase the mass fraction of the surfactant in the vice slug than in the main slug. It demonstrates that the amount of surfactant in the main slug plays a more important role in displacing oil from the formation.

  3. LETTER IN THE DIVANS BY ALİ ŞÎR NEVÂYÎ: FROM THE LOVER TO THE BELOVED AND VICE VERSA ALİ ŞÎR NEVÂYÎ’NİN DİVANLARINDA MEKTUPLAŞMA: ÂŞIKTAN SEVGİLİYE, SEVGİLİDEN ÂŞIĞA

    Directory of Open Access Journals (Sweden)

    Tülay GENÇTÜRK DEMİRCİOĞLU

    2010-07-01

    Full Text Available Concerning the relationships between the lover and the beloved in classical Turkish literature, one of the indications of falling in love is the lover’s communication with the beloved by letter. This paper examines how Ali Şîr Nevâyî, a well-known Chagatai poet who had a remarkable influence on classical Turkish literature, exercised the letter metaphor by focusing on his four divans: Garâibü’s-sıgar, Nevâdirü’ş-şebâb, Bedâyiü’l-vasat. The main argument of the present paper is that the letter metaphore was extremely used in the divans by Nevâyî in comparison to Ottoman poets of classical literature, and that this is due to utmost importance Nevâyî gives to composing yek-ahenk gazals. Klasik Türk edebiyatının aşk-âşık-maşuk üçgeninde âşıklığın göstergelerinden biri de sevgili ve âşığın mektuplaşmasıdır. Bu makalede klasik Türk edebiyatında etkisi büyük olan Çağatay şairi Ali Şîr Nevâyî’nin dört divanı Garâibü’s-sıgâr, Nevâdirü’ş-şebâb, Bedâyiü’l-vasat ve Fevâyidü’l-kiber taranmış, şiirlerinde mektup kavramı bütün yönleriyle; vasıfları, çeşitleri, ilgili teşbihler ve mektuplaşma geleneği incelenmiştir. Makale, bu kavramın Nevâyî’nin divanlarında Anadolu sahasındaki Türk şairlerine kıyasla daha geniş yer bulduğunu, bunun nedeninin de şairin yek-ahenk gazel yazmaya verdiği önemden kaynaklandığını ileri sürmektedir.

  4. Making the Case for Early Childhood Investments: Three Arguments

    Science.gov (United States)

    Neugebauer, Roger

    2011-01-01

    Tamar Manuelyan Atinc, vice president of The World Bank, introduces a World Bank report, "Investing in Young Children: An Early Childhood Development Guide for Policy Dialogue and Project Preparation". This report, which is a must for inclusion in every advocate's make the case for investing in early childhood services. It defines three arguments…

  5. 31 March 2016 - Qatar Foundation Research and Development Executive Vice President H. Al-Ibrahim signing a Cooperation Agreement with CERN Director-General F. Gianotti.

    CERN Multimedia

    Brice, Maximilien

    2016-01-01

    Dr Hamad Al-Ibrahim Executive Vice President, Qatar Foundation Research and Development. Were present: CERN International Relations Unit, Adviser for Qatar P. Fassnacht; CERN Director for Research and Computing E. Elsen; Texas A&M Professor of Physics A. Safonov ; CERN Director for International Relations C. Warakaulle; Professor of Physics, Qatar University I.Al-Qaradawi; Executive Vice President H. Al-Ibrahim; CERN Director-General F. Gianotti; Ambassador Faisal Bin Abdulla Al-Henzab to the UNOG; Director of Research Computing, Texas A&M, Qatar O. Bouhali; Vice Dean, Texas A&M, Qatar E. Massad; Executive Director, Research Coordination & Special Initiatives, Qatar Foundation R&D D. Khoury.

  6. A randomized crossover trial on the effect of compression stockings on nausea and vomiting in early pregnancy.

    Science.gov (United States)

    Mendoza, Erika; Amsler, Felix

    2017-01-01

    This study aimed to assess the impact of wearing compression stockings on women's quality of life (QoL) associated with nausea and vomiting in early pregnancy (NVP). In this randomized, open, single-center, crossover study, 74 women were assigned 1:1 to 2 weeks with compression stockings followed by 2 weeks without or vice versa. The main outcomes were NVP-associated QoL, leg-related QoL, and dizziness, as assessed by the Nausea and Vomiting in Pregnancy Quality of Life (NVPQOL) questionnaire, Chronic Venous Disease Quality of Life (CIVIQ) questionnaire, and questions on dizziness at baseline and after each 2-week period, respectively. Daily NVP was assessed using the modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) questionnaire. Data were analyzed using Pearson's chi-square and independent t-tests. Fifty-eight women completed the study. QoL scores improved with compression treatment; changes in mean total scores were as follows: NVPQOL, -36.7 with compression vs -21.7 without (P<0.0001); and CIVIQ, -4.5 with compression vs +1.4 without (P=0.001). Mean dizziness scores were -3.2 with compression vs -0.4 without (P<0.0001). PUQE mean total score (standard deviation) was 4.9 (2.3) with compression vs 5.5 (2.2) without (P=0.042). Wearing of compression stockings in early pregnancy may improve nausea and vomiting-associated symptoms in addition to improving QoL factors.

  7. Concordance between inflammation at physical examination and on MRI in patients with early arthritis.

    Science.gov (United States)

    Krabben, A; Stomp, W; Huizinga, T W J; van der Heijde, D; Bloem, J L; Reijnierse, M; van der Helm-van Mil, A H M

    2015-03-01

    MRI is increasingly used to measure inflammation in rheumatoid arthritis (RA) research, but the correlation to clinical assessment is unexplored. This study determined the association and concordance between inflammation of small joints measured with MRI and physical examination. 179 patients with early arthritis underwent a 68 tender joint count and 66 swollen joint count and 1.5T MRI of MCP (2-5), wrist and MTP (1-5) joints at the most painful side. Two readers scored synovitis and bone marrow oedema (BME) according to the OMERACT RA MRI scoring method and assessed tenosynovitis. The MRI data were first analysed continuously and then dichotomised to analyse the concordance with inflammation at joint examination. 1790 joints of 179 patients were studied. Synovitis and tenosynovitis on MRI were independently associated with clinical swelling, in contrast to BME. In 86% of the swollen MCP joints and in 92% of the swollen wrist joints any inflammation on MRI was present. In 27% of the non-swollen MCP joints and in 66% of the non-swollen wrist joints any MRI inflammation was present. Vice versa, of all MCP, wrist and MTP joints with inflammation on MRI 64%, 61% and 77%, respectively, were not swollen. BME, also in case of severe lesions, occurred frequently in clinically non-swollen joints. Similar results were observed for joint tenderness. Inflammation on MRI is not only present in clinically swollen but also in non-swollen joints. In particular BME occurred in clinically non-inflamed joints. The relevance of subclinical inflammation for the disease course is a subject for further studies. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  8. Being well-liked predicts increased use of alcohol but not tobacco in early adolescence.

    Science.gov (United States)

    Van Ryzin, Mark J; DeLay, Dawn; Dishion, Thomas J

    2016-02-01

    Although substance use has traditionally been linked to peer deviance, a parallel literature has explored the influence of peer social status (being "well-liked"). This literature hypothesizes that adolescents with higher status will anticipate shifts in social norms and modify their behavior earlier and/or more substantially than lower-status students. As substance use becomes more socially acceptable during early-to-mid-adolescence, higher status youth are hypothesized to reflect this shift in norms by accelerating their use more rapidly than lower status youth. Although some evidence exists to support this hypothesis, it has never been evaluated in conjunction with the opposing hypothesis (i.e., that substance use contributes to elevated peer status). In this study, we evaluated reciprocal links between peer status and substance use (i.e., alcohol and tobacco) using 3years of data from 8 middle schools in the Pacific Northwest. Social network analysis enabled us to model standard network effects along with unique effects for the influence of the network on behavior (i.e., increased substance use as a result of being well-liked) and the influence of behavior on the network (i.e., increased status as a result of substance use). Our results indicated significant bidirectional effects for alcohol use but no significant effects for tobacco use. In other words, being well-liked significantly predicted alcohol use and vice versa, but these processes were not significant for tobacco use. Prevention efforts should consider the dynamics of peer status and peer norms in adolescence with the goal of preventing escalations in problem behavior that can compromise future adjustment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Can lncRNAs be indicators for the diagnosis of early onset or acute schizophrenia and distinguish major depressive disorder and generalized anxiety disorder?-A cross validation analysis.

    Science.gov (United States)

    Cui, Xuelian; Niu, Wei; Kong, Lingming; He, Mingjun; Jiang, Kunhong; Chen, Shengdong; Zhong, Aifang; Li, Wanshuai; Lu, Jim; Zhang, Liyi

    2017-06-01

    Depression and anxiety are apparent symptoms in the early onset or acute phase of schizophrenia (SZ), which complicate timely diagnosis and treatment. It is imperative to seek an indicator to distinguish schizophrenia from depressive and anxiety disorders. Using lncRNA microarray profiling and RT-PCR, three up-regulated lncRNAs in SZ, six down-regulated lncRNAs in major depressive disorder (MDD), and three up-regulated lncRNAs in generalized anxiety disorder (GAD) had been identified as potential biomarkers. All the lncRNAs were, then, cross-validated in 40 SZ patients, 40 MDD patients, 40 GAD patients, and 40 normal controls. Compared with controls, three up-regulated SZ lncRNAs had a significantly down-regulated expression in GAD, and no remarkable differences existed between MDD and the controls. Additionally, the six down-regulated MDD lncRNAs were expressed in an opposite fashion in SZ, and the expression of the three up-regulated GAD lncRNAs were significantly different between SZ and GAD. These results indicate that the expression patterns of the three up-regulated SZ lncRNAs could not be completely replicated in MDD and GAD, and vice versa. Thus, these three SZ lncRNAs seem to be established as potential indicators for diagnosis of schizophrenia and distinguishing it from MDD and GAD. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  10. The vices of emperor Constans I in the fourth century histories

    Directory of Open Access Journals (Sweden)

    Milivojević Uroš

    2008-01-01

    Full Text Available The aim of this paper is to analyze the negative characteristics of the Roman emperor Constans I (337-350, according to the earliest preserved information from the late 4th century histories of Aurelius Victor, Eutropius Pseudo-Victor and Eunapius of Sardis. The earliest account of Constans' downfall is around 361 recorded by Aurelius Victor in his short history De Caesaribus. Victor wrote that Constans became more arrogant and aggressive after he defeated his elder brother Constantine II in 340. Also, he was not cautious enough for his young age, was hated due to his bad subordinates and did not respect his soldiers properly. But, the most outrageous fact was according to Victor, that the emperor had homosexual affinity towards his young and attractive barbarian hostages. The record of less moralistic Eutropius in his Breviarium ab Urbe condita, written in 369, is shorter but sharper. In the beginning the reign of Constans was vigorous and righteous but his character deteriorated after his illness. Following that, the young Augustus befriended himself with corrupted companions and turned to severe vices. His reign grew unbearable to his subjects and unpopular among the army ranks. Briefer then Eutropis is the testimony of an anonymous Latin author of Epitome de caesaribus who was contemporary to the Eastern Roman emperor Arcadius (395-408. This Pseudo-Victor wrote down that Constans devoted himself to hunting session, thus allowing plotters to dethrone him. Finally the single Greek author in this series, Eunapius (died after 404, whose istoria h meta Dexippon survived in fragments and Zosimus' late fifth century abridgment, called Constans the worst among the most intolerable tyrants. The Lydian sophist, as far as we could conclude from Zosimus', also recorded Constans' inclination towards young barbarians whom he allowed to mistreat his subjects. Because of wretchedness in the provinces of his realm, the courtiers led coup d'etat through

  11. [Business, politics, science, and visa versa: an institutional history of Brazilian medical journalism between 1827 and 1843].

    Science.gov (United States)

    Ferreira, Luiz Otávio

    2004-01-01

    This analysis of Brazil's first medical newspapers - Propagador das Ciências Médicas (1827-28); Semanário de Saúde Pública (1831-33); Diário de Saúde (1835-36); Revista Médica Fluminense (1835-41); Revista Médica Brasileira (1841-43) - shows how Rio de Janeiro's socio-cultural context made it possible for this type of publication to emerge within the city's dynamic, troubled environment of the 1820s and 30s. I argue that the distinguishing feature of Brazil's early medical journalism was a symbiosis between business (local publishing houses' commercial interests), politics (struggles for political hegemony during the consolidation of the Imperial State), and science (the movement to institutionalize medicine and affirm it as a science).

  12. White House Office of the Vice President Announces New Memorandum of Understanding in Clinical Proteogenomics Between the United States and Australia | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The White House Office of the Vice President has announced the signing of three Memoranda of Understanding (MOUs) that will make available an unprecedented international dataset to advance cancer research and care.

  13. Evaluating Investments in Natural Gas Vehicles and Infrastructure for Your Fleet: Vehicle Infrastructure Cash-Flow Estimation -- VICE 2.0; Clean Cities, Energy Efficiency & Renewable Energy (EERE)

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, John

    2015-04-02

    Presentation by Senior Engineer John Gonzales on Evaluating Investments in Natural Gas Vehicles and Infrastructure for Your Fleet using the Vehicle Infrastructure Cash-flow Estimation (VICE) 2.0 model.

  14. 24 February 2012 - Polish Vice-Rectors AGH University of Science and Technology Cracow visiting the ATLAS underground experimental area with Former Collaboration Spokesperson P. Jenni; Vice Rector J. Lis signs a collaboration agreement with A. Unnervik; Adviser T. Kurtyka and A. Siemko accompany the delegation throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    24 February 2012 - Polish Vice-Rectors AGH University of Science and Technology Cracow visiting the ATLAS underground experimental area with Former Collaboration Spokesperson P. Jenni; Vice Rector J. Lis signs a collaboration agreement with A. Unnervik; Adviser T. Kurtyka and A. Siemko accompany the delegation throughout.

  15. Adjoint(e) de direction à la Vice-présidente, Stratégie générale et ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Résumé des fonctions Sous la direction de la vice-présidente, Stratégie générale et communications, et relevant du conseiller principal en stratégie et communications, l'adjoint de direction fournit de l'appui en secrétariat et en administration au BVP-SGC, et en particulier à la vice présidente, procurant un vaste éventail de ...

  16. Combining food type(s) and food quantity choice in a new food choice paradigm based on vice-virtue bundles.

    Science.gov (United States)

    Haws, Kelly L; Liu, Peggy J

    2016-08-01

    Given the prevalence and rising rates of obesity in many countries, including the United States, much food decision-making research ultimately aims at understanding how consumers can make healthier choices. The two predominant choice paradigms used in food decision-making research ask consumers to choose (a) between a "vice" (or unhealthy food) and a "virtue" (or healthy food) or (b) among varying portion sizes of "vice." We propose a new food choice paradigm that encourages consumers to jointly consider both food type(s) choice and food portion size at each decision point. The purpose of this paradigm is two-fold. First, it aims to allow examination of more comprehensive eating behavior (e.g., to examine the overall composition of a plate of food rather than choice of a single food). Second, it aims to shift consumers towards including large proportions of virtues and smaller proportions of vice in their overall consumption portfolios. For this paradigm, we draw upon a recently introduced food product innovation called "vice-virtue bundles" (Liu et al., 2015) that illustrates the basis of this new food choice paradigm, in which food type(s) and portion decisions are made simultaneously. Accordingly, we first discuss relevant findings on vice-virtue bundles as well as the differences between simultaneous and sequential choice of multiple products. Second, we examine the benefits for managing and controlling one's consumption that are provided by vice-virtue bundles and this joint food choice paradigm more generally. Third and finally, we point out opportunities for future research by discussing (a) multiple factors that influence food choices, (b) decision processes affected by food choice paradigms, and (c) issues of generalizability related to the presence of vice-virtue bundles. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. A new era begins: an official statement by Romanian Vice-Minister of Health Professor Bogdan Marinescu.

    Science.gov (United States)

    Marinescu, B

    1990-06-01

    Dr. Bogdan Marinescu, Vice-Minister of Health, is responsible for mother and child care, prevention and care in schools and universities, and the newly created Family Planning Unit. The repeal, on December 25, 1989, of the law on abortion created the legal environment for the implementation of a national family planning program (FPP). The new program will be offered to all women who want it. Special attention will be given to women having an abortion. The primary objectives of the overall FPP of the Ministry of Health consists of decreasing maternal mortality and morbidity caused by abortion and facilitating the switch from using abortion techniques to modern contraceptive techniques. The 1st step will be the nomination of a head of the FP unit who could be either a gynecologist or and administrator advised by a gynecologist. The unit head will immediately create an operational task force. The Vice-Minister will chair the task force, with the unite head acting as secretary. There will be 9 officers in the task force: the head of the FPP and a senior gynecologist from one of the teaching hospitals, and the senior nursing tutor from the post-basic training college for nurses, the senior FP health statistician, the head of health education, a representative from the Romanian FP association and a consumer. The main goal of the task force is to facilitate the development of the program by advising the Vice-Minister on all issues pertaining to FP. The creation, on April 3, 1990, of a Society for Education in Contraception (SECS) will facilitate communication among, and education of, the public and specific groups at risk, such as adolescents. The family planning program will be progressively established, starting with the university teaching hospitals, and spreading to district and town hospitals, then polyclinics. Only obstetricians and gynecologists will be allowed, at least during this 1st phase, to prescribe contraceptives. The new contraceptives introduced in the

  18. The wider social environment and changes in self-reported quality of life in the transition from late childhood to early adolescence: a cohort study

    Directory of Open Access Journals (Sweden)

    Schneiders Josien

    2006-05-01

    Full Text Available Abstract Background Neighbourhood socioeconomic disadvantage and social capital have been associated with adolescent well-being, but the majority of studies were cross-sectional, and the time window over which the neighbourhood may impact on development is unknown. Therefore, the contribution of the neighbourhood environment to adolescents' quality of life and the course of these effects during the period of transition from childhood to early adolescence was examined. Methods A cohort of adolescents living in Maastricht (The Netherlands, with a mean age of 11.2 years at baseline and of 13.5 years at follow-up was followed. Adolescents who responded both at baseline and at follow-up were included in the analysis (n = 475. Multilevel regression analyses estimated neighbourhood effects while controlling for individual-level effects. Neighbourhood-level socioeconomic and social capital variables, individual-level confounders, and baseline values of the outcome measures were included in the models. Results None of the neighbourhood factors was associated with changes in general health or mental health over the two-year period. However, two-year exposure to greater disparity between individual level socioeconomic status on the one hand and neighbourhood level of socioeconomic status on the other (e.g. high socioeconomic status adolescents living in deprived neighbourhoods and vice versa negatively impacted on self-esteem and satisfaction. Conclusion The neighbourhood environment per se does not contribute to change in quality of life during the transition to early adolescence. However, adolescents living in families whose socioeconomic status deviates from the mean level of neighbourhood socioeconomic deprivation may be negatively affected.

  19. Early processing of emotional faces in a Go/NoGo task: lack of N170 right-hemispheric specialisation in children with major depression.

    Science.gov (United States)

    Grunewald, Madlen; Stadelmann, Stephanie; Brandeis, Daniel; Jaeger, Sonia; Matuschek, Tina; Weis, Steffi; Kalex, Virgenie; Hiemisch, Andreas; von Klitzing, Kai; Döhnert, Mirko

    2015-09-01

    Emotionally biased information processing towards sad and away from happy information characterises individuals with major depression. To learn more about the nature of these dysfunctional modulations, developmental and neural aspects of emotional face processing have to be considered. By combining measures of performance (attention control, inhibition) in an emotional Go/NoGo task with an event-related potential (ERP) of early face processing (N170), we obtained a multifaceted picture of emotional face processing in a sample of children and adolescents (11-14 years) with major depression (MDD, n = 26) and healthy controls (CTRL, n = 26). Subjects had to respond to emotional faces (fearful, happy or sad) and withhold their response to calm faces or vice versa. Children of the MDD group displayed shorter N170 latencies than children of the CTRL group. Typical right lateralisation of the N170 was observed for all faces in the CTRL but not for happy and calm faces in the MDD group. However, the MDD group did not differ in their behavioural reaction to emotional faces, and effects of interference by emotional information on the reaction to calm faces in this group were notably mild. Although we could not find a typical pattern of emotional bias, the results suggest that alterations in face processing of children with major depression can be seen at early stages of face perception indexed by the N170. The findings call for longitudinal examinations considering effects of development in children with major depression as well as associations to later stages of processing.

  20. Aznar, Hanotin, and May (eds., À la place du roi. Vice-rois, gouverneurs et ambassadeurs dans les monarchies française et espanole (Casa de Velázquez, 2014

    Directory of Open Access Journals (Sweden)

    Lisandra Estevez

    2016-06-01

    Full Text Available The French and Spanish courts were two of the most powerful cultural and political institutions in seventeenth-century Europe.  Both rivals and allies, the French and Spanish crowns were bound by disputes and diplomacy.  This anthology examines the Gallic and Iberian court systems from a comparative approach, filling an important lacuna in early modern political studies and diplomatic history.  It is based on the proceedings of a seminar held at the Casa de Velázquez, Madrid in June 2010. Edited by Daniel Aznar, Guillaume Hanotin and Niels F. May, À la place du roi. Vice-rois, gouverneurs et ambassadeurs dans les monarchies française et espanole (XVIe-XVIIIe siècles unites ten essays by leading scholars of seventeenth-century French and Spanish history.

  1. Early and Partial Reduction in CD4+Foxp3+ Regulatory T Cells during Colitis-Associated Colon Cancer Induces CD4+ and CD8+ T Cell Activation Inhibiting Tumorigenesis.

    Science.gov (United States)

    Olguín, Jonadab E; Medina-Andrade, Itzel; Molina, Emmanuel; Vázquez, Armando; Pacheco-Fernández, Thalia; Saavedra, Rafael; Pérez-Plasencia, Carlos; Chirino, Yolanda I; Vaca-Paniagua, Felipe; Arias-Romero, Luis E; Gutierrez-Cirlos, Emma B; León-Cabrera, Sonia A; Rodriguez-Sosa, Miriam; Terrazas, Luis I

    2018-01-01

    Colorectal cancer (CRC) is the second most commonly diagnosed cancer in women and the third in men in North America and Europe. CRC is associated with inflammatory responses in which intestinal pathology is caused by different cell populations including a T cell dysregulation that concludes in an imbalance between activated T (Tact) and regulatory T (Treg) cells. Treg cells are CD4+Foxp3+ cells that actively suppress pathological and physiological immune responses, contributing to the maintenance of immune homeostasis. A tumor-promoting function for Treg cells has been suggested in CRC, but the kinetics of Treg cells during CRC development are poorly known. Therefore, using a mouse model of colitis-associated colon cancer (CAC) induced by azoxymethane and dextran sodium sulfate, we observed the dynamic and differential kinetics of Treg cells in blood, spleen and mesenteric lymph nodes (MLNs) as CAC progresses, highlighting a significant reduction in Treg cells in blood and spleen during early CAC development, whereas increasing percentages of Treg cells were detected in late stages in MLNs. Interestingly, when Treg cells were decreased, Tact cells were increased and vice versa. Treg cells from late stages of CAC displayed an activated phenotype by expressing PD1, CD127 and Tim-3, suggesting an increased suppressive capacity. Suppression assays showed that T-CD4+ and T-CD8+ cells were suppressed more efficiently by MLN Treg cells from CAC animals. Finally, an antibody-mediated reduction in Treg cells during early CAC development resulted in a better prognostic value, because animals showed a reduction in tumor progression associated with an increased percentage of activated CD4+CD25+Foxp3- and CD8+CD25+ T cells in MLNs, suggesting that Treg cells suppress T cell activation at early steps during CAC development.

  2. Prospective, multicenter French study evaluating the clinical impact of the Breast Cancer Intrinsic Subtype-Prosigna® Test in the management of early-stage breast cancers.

    Science.gov (United States)

    Hequet, Delphine; Callens, Céline; Gentien, David; Albaud, Benoit; Mouret-Reynier, Marie-Ange; Dubot, Coraline; Cottu, Paul; Huchon, Cyrille; Zilberman, Sonia; Berseneff, Helene; Foa, Cyril; Salmon, Rémy; Roulot, Aurélie; Lerebours, Florence; Salomon, Anne; Ghali, Nadeem; Morel, Pascale; Li, Qianyi; Cayre, Anne; Guinebretière, Jean-Marc; Hornberger, John; Penault-Llorca, Frédérique; Rouzier, Roman

    2017-01-01

    %) patients, an overall discordance rate of 25%. The availability of Prosigna assay results was significantly associated with the likelihood of change in treatment recommendations, with 34 patients (18%) having their treatment plan changed from Adjuvant Chemotherapy to No Adjuvant Chemotherapy or vice versa (puncertainty. The results of this prospective decision impact study are consistent with 2 previous, identically designed studies carried out in Spain and Germany. The availability of Prosigna test results increased the confidence of treating physicians in their adjuvant treatment decisions, and led to an 18% change in chemotherapy treatment plan (from Adjuvant Chemotherapy to No Adjuvant Chemotherapy or vice versa). Prosigna testing decreased anxiety and improved measures of health-related quality of life in patients facing adjuvant therapy. The 25% discordance between Prosigna test and IHC subtyping underlines the importance of molecular testing for optimal systemic therapy indications in early breast cancer.

  3. Virtue, Vice, and Situationism

    NARCIS (Netherlands)

    Bates, Tom; Kleingeld, Pauline; Snow, Nancy

    2018-01-01

    On the basis of psychological research, a group of philosophers known as 'situationists' argue that the evidence belies the existence of broad and stable (or 'global') character traits. They argue that this condemns as psychologically unrealistic those traditions in moral theory in which global

  4. [Interview with Dr. Miriam Schenone, Vice Minister of Justice and President of the Permanent Commission on Women's Rights].

    Science.gov (United States)

    1995-06-01

    Peru's Permanent Commission on Women's Rights is responsible for coordinating implementation of government policies pertaining to gender and for preparing for Peru's participation in the International Conference on Women to be held in Beijing in September 1995. The Commission was separated from the Permanent Commission on Rights of Women and Children in 1995 and established in the Ministry of Justice. The Commission is composed of the Vice Minister of Justice and representatives of the Ministries of Foreign Relations, Agriculture, and Labor, the National Population Council, and other organizations. The Commission's functions include proposing policy to the National Council on Human Rights and to national and international women's rights organizations, reviewing legislation, and coordinating studies pertaining to women's rights. Among activities for the Beijing Conference are preparation of the National Report on the Situation of Women and diffusion of its contents in four regional meetings throughout Peru. The National Platform contained in the Report on the Situation of Women includes proposals intended to promote gender equality and development in the areas of education, employment, income generation, and health, and elimination of all forms of violence against women.

  5. Comparison of BD Bactec Plus Blood Culture Media to VersaTREK Redox Blood Culture Media for Detection of Bacterial Pathogens in Simulated Adult Blood Cultures Containing Therapeutic Concentrations of Antibiotics▿

    OpenAIRE

    Miller, Nancy S.; Rogan, Dagmar; Orr, Beverley L.; Whitney, Dana

    2011-01-01

    Antibiotic neutralization in blood culture media from two automated systems was evaluated by measuring the recovery of organisms and times to detection in simulated cultures. Overall, BD Bactec Plus media (Bactec FX system) outperformed TREK 80 ml Redox media (VersaTREK system), although results suggest a relative rather than an absolute increased rate of recovery for the Bactec media.

  6. SU-F-T-487: On-Site Beam Matching of An Elekta Infinity with Agility MLC with An Elekta Versa HD

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, C; Garcia, M; Mason, B; Kirsner, S [UT M.D. Anderson Cancer Center, Houston, TX (United States)

    2016-06-15

    Purpose: Historically, beam matching of similar Linear Accelerators has been accomplished by sending beam data to the manufacturer to match at their factory. The purpose of this work is to demonstrate that fine beam matching can be carried out on-site as part of the acceptance test, with similar or better results. Methods: Initial scans of a 10 × 10 Percent depth dose (PDD) and a 40 × 40 beam profile at the depth of Dmax, for 6MV and 10 MV were taken to compare with the standard beam data from the Versa. The energy was then adjusted and the beam steered to achieve agreement between the depth dose and the horns of the beam profile. This process was repeated until the best agreement between PDD and profiles was achieved. Upon completion, all other clinical data were measured to verify match. This included PDD, beam profiles, output factors and Wedge factors. For electron beams PDD’s were matched and the beam profiles verified for the final beam energy. Confirmatory PDD and beam profiles for clinical field sizes, as well as Output Factors were measured. Results: The average difference in PDD’s for 6MV and 10MV were within 0.4% for both wedged and open fields. Beam profile comparisons over the central 80% of the field, at multiple depths, show agreement of 0.8% or less for both wedged and open fields. Average output factor agreement over all field sizes was 0.4% for 6MV and 0.2 % for 10MV. Wedge factors agreement was less than 0.6% for both photon energies over all field sizes. Electron PDD agreed to 0.5mm. Cone ratios agreed to 1% or less. Conclusion: This work indicates that beam matching can be carried out on-site simply and quickly. The results of this beam matching can achieve similar or better results than factory matching.

  7. 2 February 2010-Bristol University Vice-Chancellor E. Thomas visiting SM18 hall with Beams Department Head P. Collier and Technology Department Senior Engineer R. Veness; signing the guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    Caption for photograph 1239013 from left to right: University of Bristol and CMS Collaboration D. Newbold; University of Bristol Team Leader and LHCb Collaboration N. Brook; Bristol University Pro-Vice-Chancellor for Research G. Orpen; Beams Department Head P. Collier; Bristol University Vice-Chancellor E. Thomas;Technology Department Senior Engineer R. Veness in the SM18 hall.

  8. 28 June 2017 - Italian Agnelli Foundation Vice Chairman, and Fiat Chrysler Automobiles Chairman, J. Elkann signing the guest book with CERN Director-General F. Gianotti

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2017-01-01

    from left to right in 53__MA27642: Scuola di Alta Formazione al Management Project manager R. Movva; Agnelli Foundation Director A. Gavosto; Agnelli Foundation Head of Innovation A. Griva; Scuola di Alta Formazione al Management Director S. Pettochi; Agnelli Foundation Vice Chairman, and Fiat Chrysler Automobiles Chairman J. Elkann; CERN Director-General F. Gianotti; Director for International Relations C. Warakaulle; Management Liaison for the Italian Republic, Engineering Department Head R. Losito; Knowledge Transfer Group Leader G. Anelli. Signature of the Framework agreement between the Scuola di Alta Formazione al Management, represented by Director S. Petocchi and CERN, represented by Director-General F. Gianotti, witnessed by Agnelli Foundation Vice Chairman J. Elkann.

  9. SU-E-T-360: End-To-End Dosimetric Testing of a Versa HD Linear Accelerator with the Agility Head Modeled in Pinnacle3

    Energy Technology Data Exchange (ETDEWEB)

    Saenz, D; Narayanasamy, G; Cruz, W; Papanikolaou, N; Stathakis, S [University of Texas Health Science Center at San Antonio, San Antonio, TX (United States)

    2015-06-15

    Purpose: The Versa HD incorporates a variety of upgrades, primarily including the Agility head. The distinct dosimetric properties of the head from its predecessors combined with flattening-filter-free (FFF) beams require a new investigation of modeling in planning systems and verification of modeling accuracy. Methods: A model was created in Pinnacle{sup 3} v9.8 with commissioned beam data. Leaf transmission was modeled as <0.5% with maximum leaf speed of 3 cm/s. Photon spectra were tuned for FFF beams, for which profiles were modeled with arbitrary profiles rather than with cones. For verification, a variety of plans with varied parameters were devised, and point dose measurements were compared to calculated values. A phantom of several plastic water and Styrofoam slabs was scanned and imported into Pinnacle{sup 3}. Beams of different field sizes, SSD, wedges, and gantry angles were created. All available photon energies (6 MV, 10 MV, 18 MV, 6 FFF, 10 FFF) as well four clinical electron energies (6, 9, 12, and 15 MeV) were investigated. The plans were verified at a calculation point (8 cm deep for photons, variable for electrons) by measurement with a PTW Semiflex ionization chamber. In addition, IMRT testing was performed with three standard plans (step and shoot IMRT, small and large field VMAT plans). The plans were delivered on the Delta4 IMRT QA phantom (ScandiDos, Uppsala, Sweden). Results: Homogeneous point dose measurement agreed within 2% for all photon and electron beams. Open field photon measurements along the central axis at 100 cm SSD passed within 1%. Gamma passing rates were >99.5% for all plans with a 3%/3mm tolerance criteria. The IMRT QA results for the first 23 patients yielded gamma passing rates of 97.4±2.3%. Conclusion: The end-to-end testing ensured confidence in the ability of Pinnacle{sup 3} to model photon and electron beams with the Agility head.

  10. vices à des enfants ou insensibilité congénitale à la douleur?

    Science.gov (United States)

    Escard, E; Barret, L

    2003-01-01

    L’insensibilité congénitale à la douleur est une affection rare qui peut être responsable de l’apparition accidentelle de lésions externes et internes chez l’enfant. Dans un contexte de présomptions de sévices à des enfants, le fait de connaître l’existence de cette affection peut compliquer l’interprétation médico-légale de nos constatations. Le diagnostic d’insensibilité congénitale à la douleur, dans la forme qui nous intéresse, nécessite plusieurs éléments : l’absence de sensibilité à la douleur depuis la naissance, l’atteinte de la totalité de la surface corporelle, l’intégrité des réflexes ostéo-tendineux et des autres modes de sensibilité, la négativité des examens paracliniques, y compris histologiques. Nous présentons un cas de deux enfants de la même fratrie, examinés dans le cadre d’une procédure judiciaire d’urgence au sein de l’unité de médecine légale du Centre hospitalo-universitaire de Grenoble, en France. L’interprétation médicolégale des faits et de l’examen doit être prudente en cas de complications judiciaires et faire suite à une analyse des problèmes médico-sociaux de l’enfant depuis sa naissance et de ceux de sa famille. Le soutien socio-éducatif de ces familles et la transmission d’information sur cette maladie doivent être une priorité afin d’éviter tout dépassement dans la prise en charge et la surveillance de l’enfant et tout quiproquo face aux autres. PMID:20020013

  11. At the United Nation Foundation's Social Good Summit, Vice President Biden Announces New Cancer Moonshot International Cooperation and Investments | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    This week, Vice President Joe Biden announced progress on his global vision for the Cancer Moonshot.  Announced were 10 new Memoranda of Understanding or Memoranda of Cooperation for international cancer research and care, as well as new efforts in the emerging scientific areas of precision oncology, the funding of collaborative research centers to address cancer disparities in low- and middle- income (LMIC) countries, and a strengthening of existing U.S. bilateral science and technology engagements around cancer.  

  12. Improving decision speed, accuracy and group cohesion through early information gathering in house-hunting ants.

    Directory of Open Access Journals (Sweden)

    Nathalie Stroeymeyt

    Full Text Available BACKGROUND: Successful collective decision-making depends on groups of animals being able to make accurate choices while maintaining group cohesion. However, increasing accuracy and/or cohesion usually decreases decision speed and vice-versa. Such trade-offs are widespread in animal decision-making and result in various decision-making strategies that emphasize either speed or accuracy, depending on the context. Speed-accuracy trade-offs have been the object of many theoretical investigations, but these studies did not consider the possible effects of previous experience and/or knowledge of individuals on such trade-offs. In this study, we investigated how previous knowledge of their environment may affect emigration speed, nest choice and colony cohesion in emigrations of the house-hunting ant Temnothorax albipennis, a collective decision-making process subject to a classical speed-accuracy trade-off. METHODOLOGY/PRINCIPAL FINDINGS: Colonies allowed to explore a high quality nest site for one week before they were forced to emigrate found that nest and accepted it faster than emigrating naïve colonies. This resulted in increased speed in single choice emigrations and higher colony cohesion in binary choice emigrations. Additionally, colonies allowed to explore both high and low quality nest sites for one week prior to emigration remained more cohesive, made more accurate decisions and emigrated faster than emigrating naïve colonies. CONCLUSIONS/SIGNIFICANCE: These results show that colonies gather and store information about available nest sites while their nest is still intact, and later retrieve and use this information when they need to emigrate. This improves colony performance. Early gathering of information for later use is therefore an effective strategy allowing T. albipennis colonies to improve simultaneously all aspects of the decision-making process--i.e. speed, accuracy and cohesion--and partly circumvent the speed-accuracy trade

  13. Efficacy and safety of subcutaneous trastuzumab and intravenous trastuzumab as part of adjuvant therapy for HER2-positive early breast cancer: Final analysis of the randomised, two-cohort PrefHer study.

    Science.gov (United States)

    Pivot, X; Verma, S; Fallowfield, L; Müller, V; Lichinitser, M; Jenkins, V; Sánchez Muñoz, A; Machackova, Z; Osborne, S; Gligorov, J

    2017-11-01

    To assess efficacy (event-free survival, EFS) and safety in patients followed up for 3 years in the PrefHer study (NCT01401166). Post surgery and post chemotherapy in the (neo)adjuvant setting, patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer were randomised to receive four cycles of the subcutaneous form of trastuzumab (Herceptin ® SC [H SC] via single-use injection device [Cohort 1] or delivery via a hand-held syringe from an SC Vial [Cohort 2]; 600 mg fixed dose) followed by four of the intravenous form of trastuzumab (Herceptin ® [H IV]; 8 mg/kg loading, 6 mg/kg maintenance doses) in the adjuvant setting or vice versa every 3 weeks. Patients could have received H before randomisation. H was then continued to complete a total of 18 cycles, including any cycles received before randomisation. A total of 488 patients were randomised across both cohorts. After median follow-up of 36.1 months, 3-year EFS across both groups in the evaluable intention-to-treat population (467 patients) was 90.6% overall, 89.9% in Cohort 1, and 91.1% in Cohort 2. No new safety signals were identified during long-term follow-up, with only one cardiac serious adverse event in the safety population (483 patients). Three-year EFS data following H SC and H IV treatment are consistent with those reported by previous trials for H in the adjuvant setting. The overall safety profile during adjuvant treatment was as expected. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. The Centre for Early Human Behaviour (EHB) at the University of Bergen: A transdisciplinary exploration into the evolution of homo sapiens behaviour

    Science.gov (United States)

    Sobolowski, Stefan; Henshilwood, Christopher; Jansen, Eystein

    2017-04-01

    how did the 'switch' occur; b) were there changes in the human brain at that time that accelerated behavioural variability and how can these be measured now? Secondary linked tasks address the social organization of these early humans: was social cohesion enhanced by symbolic material culture or vice-versa and did it lead to innovation; what cognitive skills had to be in place in order for other skills to develop; how adaptable were humans to environmental change and did climate act as a driver for technological innovation, social change and subsistence adaptations? This presentation will introduce the recently awarded center, its key objectives and ambitions, and serve as an open invitation to collaboration and intellectual engagement on this exciting topic.

  15. Conference RSIS (The role of science in the information society) - Contributions to Economic Development - Building 40 S2 - B01 - Mr. Mohammad Nahavandian, Vice-President for Research, Institute for Humanities and Cultural Studies, Tehran.

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Conference RSIS (The role of science in the information society) - Contributions to Economic Development - Building 40 S2 - B01 - Mr. Mohammad Nahavandian, Vice-President for Research, Institute for Humanities and Cultural Studies, Tehran.

  16. Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa exchanging gifts at luncheon and signing the Guest Book on 1st November 2007 with CERN Director-General R. Aymar.

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa exchanging gifts at luncheon and signing the Guest Book on 1st November 2007 with CERN Director-General R. Aymar.

  17. Signature in the microcosm with Professor Bas S.C.J.J. Kortmann, Rector Magnificus Dr Anton A.J.M. Franken, Vice President Radboud University Nijmegen Kingdom of the Netherlands and Dr. Jos Engelen, Chief Scientific Officer of CERN.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Signature in the microcosm with Professor Bas S.C.J.J. Kortmann, Rector Magnificus Dr Anton A.J.M. Franken, Vice President Radboud University Nijmegen Kingdom of the Netherlands and Dr. Jos Engelen, Chief Scientific Officer of CERN.

  18. Mr Huidong LI Deputy Chairman and Secretary-General, Rev. Committee of Chinese Nationalist Party Vice President, Sun Yat-Sen Culture Interchange Association of China Member, Committee for Internal and Judicial Affairs of the National People's Congress of China

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2017-01-01

    Mr Huidong LI Deputy Chairman and Secretary-General, Rev. Committee of Chinese Nationalist Party Vice President, Sun Yat-Sen Culture Interchange Association of China Member, Committee for Internal and Judicial Affairs of the National People's Congress of China

  19. 1st October 2010 - Chinese Vice President of the Academy of Sciences signing the guest book and exchanging gifts with CERN Director for Research and Scientific Computing S. Bertolucci, witnessed by Adviser R. Voss

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    1st October 2010 - Chinese Vice President of the Academy of Sciences signing the guest book and exchanging gifts with CERN Director for Research and Scientific Computing S. Bertolucci, witnessed by Adviser R. Voss

  20. 28 October 2013- Former US Vice President A. Gore signing the guest book with Technology Department Head F. Bordry, Head of International Relations R. Voss, Director for Research and Scientific Computing S. Bertolucci and CMS Collaboration Spokesperson J. Incandela.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    28 October 2013- Former US Vice President A. Gore signing the guest book with Technology Department Head F. Bordry, Head of International Relations R. Voss, Director for Research and Scientific Computing S. Bertolucci and CMS Collaboration Spokesperson J. Incandela.

  1. 29 January 2013 - Japanese Toshiba Corporation Executive Officer and Corporate Senior Vice President O. Maekawa in the ATLAS visitor centre with representatives of the CERN-Japanese community led by Former Collaboration Spokesperson P. Jenni.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    29 January 2013 - Japanese Toshiba Corporation Executive Officer and Corporate Senior Vice President O. Maekawa in the ATLAS visitor centre with representatives of the CERN-Japanese community led by Former Collaboration Spokesperson P. Jenni.

  2. UK Institute of Physics (IOP) President Sir Gareth Roberts (right) at CERN on 9 July with (right to left) IOP council vice-president and distinguished physicist Peter Kalmus, CERN engineer Tim Watson and IOP director of science Peter Cooper

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    UK Institute of Physics (IOP) President Sir Gareth Roberts (right) at CERN on 9 July with (right to left) IOP council vice-president and distinguished physicist Peter Kalmus, CERN engineer Tim Watson and IOP director of science Peter Cooper

  3. Conference "Internet, Web, What's next?" on 26 June 1998 at CERN: Mark Bernstein, Vice President of CNN Interactive, describes the impact of the Web on world media and predicts what we can expect as the next developments

    CERN Multimedia

    1998-01-01

    Conference "Internet, Web, What's next?" on 26 June 1998 at CERN: Mark Bernstein, Vice President of CNN Interactive, describes the impact of the Web on world media and predicts what we can expect as the next developments

  4. 14 February 2012 - Vice-President of the Senate of the Parliament of the Czech Republic A. Gajduskova signing the guest book with CERN Director-General R. Heuer; visiting ATLAS experimental area with Collaboration Spokesperson F. Gianotti. Ambassador Sequensova to the UN accompanies the Vice-President.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    Vice-president of the Senate of the Parliament of the Czech Republic, Alena Gajduskova was welcomed to CERN by Rolf Heuer, CERN’s director-general, on 14 and 15 February. Her time at CERN included the ATLAS Visitor Centre and underground experimental area, the LHC tunnel, the LHC superconducting-magnet test hall and the ALICE underground experimental area. She also heard a presentation on the LHC Computing Grid Project at CERN’s Computer Centre.

  5. Servir la Couronne: Les faux-pas du comte de Baños, vice-roi de la Nouvelle-Espagne (1660-1664

    Directory of Open Access Journals (Sweden)

    Ragon, Pierre

    2010-06-01

    Full Text Available Not available.

    A los pocos días de su llegada, el conde de Baños se enfrentó con los habitantes de su Virreinato: le culparon de ser arrogante, despectivo y de llevarse el dinero del rey. Tal concierto de quejas y denuncias en contra de un personaje tan eminente era algo bastante excepcional aunque, sí, no lo era su conducta ¿Cómo explicarlo? Entre la necesaria mano dura que exigiría un contexto difícil y el temperamento peculiar del mismo virrey, aquí se explora una tercera hipótesis, haciendo hincapié en el estatuto peculiar de la familia aristocrática a la que pertenecía y su trayectoria propia. [fr] Peu de temps après son arrivée, le comte de Baños vit se dégrader ses relations avec les habitants de la vice-royauté qu’il administrait: on l’accusa d’être arrogant, méprisant et de voler l’argent du roi. Une telle série d’attaques contre un personnage aussi haut placé était assez exceptionnelle même si ses écarts de conduite n’avaient rien d’inhabituel. Comment expliquer ce paradoxe? On a jusque-là évoqué les difficultés du moment qui exigeaient que le gouvernant se montrât ferme ainsi que le tempérament du vice-roi. Ici, une troisième hypothèse est explorée à partir de la prise en compte du caractère particulier de son statut au sein de l’aristocratie espagnole et de la trajectoire de sa famille.

  6. 26th February 2009 - US Google Vice President and Chief Internet Evangelist V. Cerf signing the guest book with Director for research and Computing S. Bertolucci; visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni.

    CERN Multimedia

    Maximilien Brice

    2009-01-01

    HI-0902038 05: IT Department Head, F. Hemmer; US Google Vice President and Chief Internet Evangelist V. Cerf; Computing Security Officer and Colloquium Convenor D. R. Myers; Member of the Internet Society Advisory Council F. Flückiger; Director for Research and Scientific Computing, S. Bertolucci ; Honorary Staff Member, B. Segal. HI-0902038 16: Computing Security Officer and Colloquium Convenor D. R. Myers; UC Irvine, ATLAS Deputy Spokesperson elect A. J. Lankford; US Google Vice President and Chief Internet Evangelist V. Cerf; ATLAS Collaboration Spokesperson P. Jenni; IT Department Head, F. Hemmer.

  7. Have I Been a Data Scientist from the Start? Parallels from the Geographic Information Science Community in the Early 1990s

    Science.gov (United States)

    Wright, D. J.

    2013-12-01

    In the early 1990s the author came of age as the technology driving the geographic information system or GIS was beginning to successfully 'handle' geospatial data at a range of scales and formats, and a wide array of information technology products emerged from an expanding GIS industry. However, that small community struggled to reflect the diverse research efforts at play in understanding the deeper issues surrounding geospatial data, and the impediments to that effective use of that data. It was from this need that geographic information science or GIScience arose, to ensure in part that GIS did not fall into the trap of being a technology in search of applications, a one-time, one-off, non-intellectual 'bag of tricks' with no substantive theory underpinning it, and suitable only for a static period of time (e.g., Goodchild, 1992). The community has since debated the issue of "tool versus science' which has also played a role in defining GIS as an actual profession. In turn, GIS has contributed to "methodological versus substantive" questions in science, leading to understandings of how the Earth works versus how the Earth should look. In the author's experience, the multidimensional structuring and scaling data, with integrative and innovative approaches to analyzing, modeling, and developing extensive and spatial data from selected places on land and at sea, have revealed how theory and application are in no way mutually exclusive, and it may often be application that advances theory, rather than vice versa. Increasingly, both the system and science of geographic information have welcomed strong collaborations among computer scientists, information scientists, and domain scientists to solve complex scientific questions. As such, they have paralleled the emergence and acceptance of "data science." And now that we are squarely in an era of regional- to global-scale observation and simulation of the Earth, produce data that are too big, move too fast, and do not

  8. Pseudomorphic Stabilization of Diamond on Non-Diamond Substrates. Part 1. Diamond Grown on Single Crystal Beryllium Oxide. Part 2. Anomalous Band Gap Behavior and Phase Stability of c-BN/Diamond Alloys

    Science.gov (United States)

    1992-10-12

    at (I13, 2/3, 0) and 0 at (i/3, 2/3, 3/8) or vice versa. This structure (Table I) is geometrically similar to Lonsdaleite (hexagonal diamond) and thus...thin crystal of Lonsdaleite with the ABAB... stacking sequence can be achieved in the early stages of diamond growth.- 4 .25 After the elimination of the

  9. Cross contamination in dual inlet isotope ratio mass spectrometers

    NARCIS (Netherlands)

    Meijer, H.A.J.; Neubert, R.E.M.; Visser, G.H.

    2000-01-01

    Since the early days of geochemical isotope ratio mass spectrometry there has always been the problem of cross contamination, i.e. the contamination of the sample gas with traces of reference gas land vice versa) in a dual inlet system and the analyzer itself. This was attributable to valve leakages

  10. [The advantage of multidisciplinary treatment of presbycusis].

    Science.gov (United States)

    Bouccara, Didier; Madjlessi, Arach; Mosnier, Isabelle

    2010-01-01

    Attributable to the ageing of the hearing system, presbycusis presents a wide variability in the general population. Early detection is necessary in order to be able to provide the patient with a suitable hearing aid. Collaboration between otolaryngologists and geriatricians proves to be advantageous as a consultation for a memory complaint may be the opportunity to detect presbycusis and vice versa.

  11. Message from Vice Chancellor, UMP

    Science.gov (United States)

    Nasir Ibrahim, Daing

    2012-09-01

    Assalamualaikumwarahmatullahiwabarakatuh and Salam i Malaysia First and foremost, I want to thank the International Conference Mechanical Engineering Research (ICMER) organisers for inviting me to address and officiate at this conference. It is a privilege and an honour for me on this momentous occasion to grace the ceremony. The ICMER provides a platform to bring together not only researchers but also postgraduate students in Mechanical Engineering, Automotive Engineering, Manufacturing Engineering, Biomechanical Engineering, Material Engineering and Industrial Engineering. With this platform, ICMER will embark on a whole process of making new discoveries and then translating them into products and services for the marketplace; this is only made possible by people like all of you. It might be only a starting point but with hard work and perseverance I am sure you will succeed with flying colours. As one of Malaysia's Public Universities, UMP's main challenge is to remain competitive and relevant by offering high quality technical academic programmes and research activities, focusing on its niche areas. New knowledge and findings cannot be generated without research and development (R&D) therefore, Malaysia has had substantial investment in research and development facilities. These efforts will undoubtedly generate lots of interesting results and new knowledge as either further investigation or commercial activities. Therefore, researchers like you must see this as the generator of new knowledge to extend your research outcomes from laboratory experiments to the marketplace and towards commercialisation. Naybe this doesn't appear significant in the short term but it may make a tremendous impact in the future. The Malaysian government has invested a huge sum of Ringgits in R&D over the years. Therefore, public universities such as UMP must produce more quality researchers and graduates to ensure Malaysia reaps the returns from these investments and consequently progressive economic growth for the country. Commensurate with these efforts, the results of research must be commercialised effectively. That is why our 2nd KRA UMP's 2011-2015 Strategic Plan determines that we strengthen and sustain its financial support by allocating research grants and industry collaboration and consultations through its business and commercialisation unit. Commercialisation of research outcomes doesn't happen naturally. It may need many man-hours and effort to be invested rather than just purchasing new tools and equipment for laboratories. Moreover, it would be unfortunate if many research results remain in the form of technical publications and scientific journals rather than actual products. These may of course be valuable in their own right but the impact on society and economies must be the main agenda and one of the objectives of the research. The process of taking technology from laboratories to the marketplace will face challenges and pitfalls. In that case we as researchers must be responsible and willing to create a supportive environment for those who undertake this risky business of commercialising R&D especially for innovative entrepreneurship that carries out a new technological approach out from the laboratories to high-tech ventures. We have achieved many accolades from numerous competitors since we first embarked on our journey to make R&D activities play a more significant role in the economy in Malaysia. Therefore, we must keep up the pace of this journey and maintain our investment in R&D despite facing the unfavourable global financial situation because ultimately we must to remain a top and competitive player in the global economy. This can be done by continuing to produce high quality research and technology which will set a milestone in transforming our economy. On behalf of UMP, I would like to express my appreciation to the all the committee members from the Faculty of Mechanical Engineering and Automotive Engineering Centre for their hard work and relentless effort. Without their commitment and c

  12. Moving Forward Vice Straight Ahead

    Science.gov (United States)

    2010-03-25

    military to be turned against itself, whether by race, religion , gender or just plain fear of one another or lack of understanding. America‘s...called for racial equality and an end to discrimination, delivered August 28, 1963. 10 Arthur Schopenhauer , http://en.wikiquote.org/wiki

  13. Diversidad florística y conservación del Santuario Regional de Piura Manglares San Pedro de Vice-Sechura

    Directory of Open Access Journals (Sweden)

    Manuel Charcape-Ravelo

    2013-05-01

    Full Text Available El presente trabajo se llevó a cabo con la finalidad de conocer la composición de las fanerógamas del Santuario Regional de Piura Manglares San Pedro de Vice-Sechura. Su importancia radica en que es el manglar más austral del Pacífico de Sudamérica. Dicho trabajo fue realizado desde abril del 2000 hasta febrero del 2004. Para la realización del presente estudio se realizaron visitas periódicas cada dos meses al lugar, se colectaron las plantas bajo procedimientos estándar. Las muestras se determinaron en el lugar y algunas fueron llevadas al laboratorio de Botánica de la Universidad Nacional de Piura y al laboratorio de Botánica Fanerogámica de la Universidad Nacional de Trujillo para su determinación definitiva; luego, las muestras se depositaron en el herbario en formación de la Universidad Nacional de Piura. El manglar consiste en primer lugar de árboles y arbustos de Avicennia germinans (L. L. (Verbenaceae «mangle prieto». En el presente inventario se documentan un total de 44 especies de fanerógamas correspondiendo a 36 géneros en 21 familias para el manglar.

  14. Top man: Mathematician, geographer, vice chancellor , Sir Alan Wilson the new director general of higher education at the DfES, has a reputation for solving complicated problems. He talks to Jim Kelly

    CERN Document Server

    Kelly, J

    2003-01-01

    "Sir Alan Wilson, vice-chancellor of Leeds University, has made a career out of solving big problems. This week he landed himself one of the biggest. Appointed the government's first ever director general of higher education, he becomes responsible for advising Charles Clarke at a pivotal moment in the history of the sector" (1 page).

  15. Women in science's family and career expectations, intentions and decisions: How do they evolve over the graduate and early career years?

    Science.gov (United States)

    Stevens, Sarah

    A wide body of research has documented that women drop out of science at each successive stage of education and career, a phenomenon known as the leaky pipeline (Goulden, Frasch & Mason, 2009). This phenomenon is especially evident in Atmospheric Science (ATS), a group that loses women at a higher rate than other geoscience fields (NSF, 2013). One reason for this loss is the stress of education and career on family planning and vice versa (Thiry, 2011). This conflict is particularly intense for women in dual-career relationships, perhaps related to a socialized pressure to prioritize their relationships over their careers (Canetto, Trott, Thomas, & Wynstra, 2012; Larocque, 1995). One limitation of prior studies is that they are cross-sectional. No previous research has longitudinally examined the work and family choices and experiences of female ATS graduate students. This study will do so by investigating how female graduate students in ATS think about commitment to one's partner and make decisions about job location.

  16. Opium: The Evolution of Policies, the Tolerance of the Vice, and the Proliferation of Contraband Trade in the Philippines, 1843-1908

    Directory of Open Access Journals (Sweden)

    Alma N. Bamero

    2006-12-01

    Full Text Available This research entitled “Opium: The Evolution of Policies, the Tolerance of the Vice, and the Proliferation of Contraband Trade in the Philippines, 1843-1908” presents a discussion of the opium trade in Asia, the commercial networks it created, the political ties it strengthened, and the social relations itfostered. It also aims to reconstruct an aspect of Philippine social history in the nineteenth century through the use of archival materials that bear witness to the distribution and exploitation of a substance which some people stillclassify as taboo. The poppy was not endemic to the Philippines but opium, its derivative substance, was known to numb pain and could induce a “natural high” that left one with feelings of ease and contentment. A more complete introduction to the drug necessitates a discussion of the way it was extractedand processed. It is a cash crop that does not require complex devices and is, therefore, within the reach of farmers and common folk. From the eighteenth to the nineteenth centuries opium became very popular among the Chinese who discovered that their markets were being flooded with it by the British sothat the latter could pay for the tea that they craved.The Spanish Bourbons, in an effort to boost Philippine economy, allowed the trading of this substance. Initially this was supervised by the officials of the Alcaiceria de San Fernando but in 1843 the meticulous examination of the country’s finances merited the creation of an opium revenuefarm through municipal franchising. Opium could only be used by the Chinese who were migrating in big groups. This paper presents the details of the monopoly contract, identifies some of the wealthier contratistas of the period, and discusses the consequences of such a commercial venture. Smuggling orcontraband trade proliferated and by way of illustration the events namely, the Scandal of 1843 and the Gunga Incident, have been narrated. The creation of an over

  17. 14th September 2010 - UK Birmingham University Vice Chancellor D. Eastwood signing the guest book with Director for Accelerators and Technology S. Myers (CERN-HI-1009225 13-22)

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    (CERN-HI-1009225 02-12): visiting the LHC superconducting magnet test hall with Beams Department Head P. Collier; (CERN-HI-1009225 27-34): visiting the ATLAS visitor centre with Collaboration Spokesperson F. Gianotti and Deputy D. Charlton, University of Birmingham. D.Eastwood is accompnied by Pro-Vice-Chancellor and Head of College (Engineering and Physical Sciences) N. Weatherill and Head of School, School of Physics & Astronomy A.Schofield.

  18. Early literacy

    DEFF Research Database (Denmark)

    Jensen, Anders Skriver

    2012-01-01

    This paper discusses findings from the Danish contribution to the EASE project, a European research project running from 2008 to 2010 on early literacy in relation to the transition from childcare to school. It explores a holistic, inclusive approach to early literacy that resists a narrow...... and schools. The paper also draws on Gee’s (2001, 2003, 2004, 2008) sociocultural approach to literacy, and Honneth’s (2003, 2006) concept of recognition. Emphasizing participation and recognition as key elements, it claims that stakeholders in early liter- acy must pay attention to how diverse early literacy...... opportunities empower children, especially when these opportunities are employed in a project-based learning environ- ment in which each child is able to contribute to the shared literacy events....

  19. Longitudinal Associations Among Relationship Satisfaction, Sexual Satisfaction, and Frequency of Sex in Early Marriage.

    Science.gov (United States)

    McNulty, James K; Wenner, Carolyn A; Fisher, Terri D

    2016-01-01

    The current research used two 8-wave longitudinal studies spanning the first 4-5 years of 207 marriages to examine the potential bidirectional associations among marital satisfaction, sexual satisfaction, and frequency of sex. All three variables declined over time, though the rate of decline in each variable became increasingly less steep. Controlling for these changes, own marital and sexual satisfaction were bidirectionally positively associated with one another; higher levels of marital satisfaction at one wave of assessment predicted more positive changes in sexual satisfaction from that assessment to the next and higher levels of sexual satisfaction at one wave of assessment predicted more positive changes in marital satisfaction from that assessment to the next. Likewise, own sexual satisfaction and frequency of sex were bidirectionally positively associated with one another. Additionally, partner sexual satisfaction positively predicted changes in frequency of sex and own sexual satisfaction among husbands, yet partner marital satisfaction negatively predicted changes in both frequency of sex and own sexual satisfaction. Controlling these associations, marital satisfaction did not directly predict changes in frequency of sex or vice versa. Only the association between partner sexual satisfaction and changes in own sexual satisfaction varied across men and women and none of the key effects varied across the studies. These findings suggest that sexual and relationship satisfaction are intricately intertwined and thus that interventions to treat and prevent marital distress may benefit by targeting the sexual relationship and interventions to treat and prevent sexual distress in marriage may benefit by targeting the marital relationship.

  20. Disentangling the Temporal Relationship Between Parental Depressive Symptoms and Early Child Behavior Problems: A Transactional Framework

    Science.gov (United States)

    Bagner, Daniel M.; Pettit, Jeremy W.; Lewinsohn, Peter M.; Seeley, John R.; Jaccard, James

    2015-01-01

    Despite the considerable amount of research demonstrating the relationship between parental depressive symptoms and child behavior problems, few studies have examined the direction of the relationship between these variables. Therefore, the purpose of this study was to examine transactional effects between parental depressive symptoms and child behavior problems. Participants were 209 parent-child dyads drawn from the Oregon Adolescent Depression Project who completed at least 2 of 4 annual questionnaire assessments between the child’s age of 4 and 7 years. Structural equation modeling was used to examine the autoregressive paths from one year to the next year within each construct, as well as cross-lagged paths from one year to the next year between constructs. Findings indicated that parental depressive symptoms at each year predicted child behavior problems at the subsequent year and vice versa. No support was found for differential gender effects. These findings highlight the reciprocal relationship between parental depressive symptoms and child behavior problems and suggest intervention programs for young children should assess for and target parental depression when appropriate. Future research should examine these relationships across a broader developmental spectrum and in more diverse, heterogeneous samples. PMID:22963145

  1. Will Early Retirement Retire Early?

    Science.gov (United States)

    Walker, James W.

    1976-01-01

    Management should recognize and consider both the advantages of early retirement programs and the countervailing forces of financial conditions, individual attitudes, and age discrimination laws. (Available from American Management Associations, Subscription Services, Box 319, Saranac Lake, NY 12983; $15.00 annually) (Author/MLF)

  2. Early discontinuation

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; Felde, Lina; Gichangi, Anthony

    2007-01-01

    Introduction Discontinuation of medical drug treatment is a serious problem in primary care. The need for a better understanding of the processes, including physician-specific mechanisms, is apparent. The aim of this study was to analyse the association between general practitioners' prescribing....... There was a positive association between the prevalence of prescribing for the specific drugs studied (antidepressants, antidiabetics, drugs against osteoporosis and lipid-lowering drugs) and early discontinuation (r = 0.29 -0.44), but not for anti-hypertensive drugs. The analysis of the association between prevalence...... of all drugs and drug-specific early discontinuation showed some degree of positive association - strongest for anti-hypertensive drugs (r = 0.62) and antidepressants (r = 0.43). Conclusion This study confirmed our hypothesis that general practitioners with high levels of prescribing attain higher rates...

  3. Sappho's shifting fortunes from antiquity to the early Renaissance.

    Science.gov (United States)

    Penrose, Walter

    2014-01-01

    Although Sappho was revered as the greatest woman poet of all time by the Greeks, in later antiquity and the Middle Ages, her love of women was considered shameful and overshadowed her excellent reputation. She was also called a prostitute, and fictional accounts of her affairs with men further "tarnished" her reputation. Dual representations of Sappho existed within two centuries of her death. On the one hand, she was a role model for other poets to follow in their quest for fame, on the other she was the quintessential representation of female vice, which, at least by the Roman period, brought her infamy. Late antique and medieval Christian authors inherited this latter view, and vilified Sappho's sexuality, while church authorities, at least according to legend, had her works publicly burned. In the initial stages of the Renaissance, then, the humanist desire to reconnect with the pagan past had to proceed in the context of late medieval Christianity. Sappho's homoeroticism was erased, ultimately, in order that her skill could be lauded to fight misogyny. Hence, the humanists "rehabilitated" Sappho's virtue in a Christian context where same-sex love was considered an "unmentionable" vice. In order to argue that women were smart and capable, the humanists needed Sappho. She was perhaps the most famous, and most skilled, woman who had ever lived, and her example was used in an attempt to improve the lot of women in the early Renaissance.

  4. LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women.

    Science.gov (United States)

    Sharma, Rohini; Hamilton, Anne; Beith, Jane

    2008-10-08

    combination of an LHRH agonist and tamoxifen might be better than either alone. Insufficient data are available to inform a choice between tamoxifen and goserelin as sole adjuvant therapy. We included twelve trials (more than 10,000 women) of the integration of LHRH agonists into adjuvant chemo-hormonal therapy. Four trials assessed the effects of an LHRH agonist compared to chemotherapy and three other trials investigated a combination of an LHRH agonist and tamoxifen versus chemotherapy. One trial assessed the effects of adding chemotherapy to an LHRH agonist, five trials compared a combination of an LHRH agonist and chemotherapy versus chemotherapy alone, and three trials compared the combination of LHRH agonist, tamoxifen and chemotherapy versus chemotherapy alone. No trials compared an LHRH agonist containing regimen against chemotherapy and tamoxifen. No significant differences in recurrence free survival or overall survival were found between LHRH agonists, with or without adjuvant tamoxifen, and chemotherapy for premenopausal women with ER+ tumours, but hormonal therapy had fewer distressing side effects. The trials point to reductions in recurrence and death for premenopausal women with ER+ tumours who take LHRH agonists, with or without tamoxifen, along with chemotherapy. For premenopausal women with early breast cancer who are not known to be ER negative, the use of an LHRH agonist, with or without tamoxifen as adjuvant therapy is likely to lead to a reduction in the risk of recurrence and a delay in death. The evidence is insufficient to support the LHRH agonists over chemotherapy, or vice versa, in regard to recurrence free survival and overall survival, but LHRH agonists have fewer or less severe adverse effects. Further follow-up of women in these trials is needed to provide reliable evidence on long term outcomes. Direct randomised comparisons of different durations of LHRH agonists (for example, two years versus longer) and, in the presence of uncertainty, of

  5. Basic promotion study on joint implementation. Feasibility study of introducing vice system to Klang valley and multimedia super corridor in Malaysia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A survey is conducted about the feasibility of introduction of the vehicle information and communication system (VICS) as clean development mechanism (CDM) into Klang Valley and Multimedia Super Corridor. A real-time car navigation system is recommended as the integrated traffic information service (IT IS) to be adopted. For communication, an FM multiplex broadcasting system is to be employed. Investment of RM42.4 million will be necessary. Fuel equal to 4,850 tons/year in terms of crude oil will be saved, and CO2 emissions will be reduced by 11,200 tons/year. As for 10-year average cost performance, it will be 20.2 tons/million yen in crude oil and 46.6 tons/million yen in CO2. The schedule is that designing of the details will be started in 2000 for implementation in 2004. Since ITIS in spite of the relatively small fund it demands will bring about great merits relative to road traffic information, it is recommended that it be introduced at an early date. Although the project is feasible technologically and economically, yet a number of problems have to be solved before realization. It is necessary to have various organizations concerned, government offices, and communication-related sectors accept the necessity of the system, to determine the roles for them to assume, and to set up a cooperative and harmonious working system. Problems will also surface involving private business activities. (NEDO)

  6. Practical Applications of the Standardised Precipitation Index (SPI) as a Tool for Very Early Warning of Droughts and Floods in the Balkans Region

    Science.gov (United States)

    Faulkner, Brian

    2016-04-01

    where rainfall is normally low during a month, large negative or positive SPIs may result even though the departure from the mean is relatively small, and the associated precipitation deficit will also be small. Conversely, a moderate SPI value in a high(er) precipitation month is likely to be much more significant with regard to precipitation 'hazard'. The paper therefore illustrates within the SPI procedures the parallel use of a 'Precipitation Hazard Index' (PHI) which employs two key principles: • The relative value of the SPI 1, 2, n is transformed to the PHI by simply by multiplying the SPI x the precipitation mean value for the same time period. The resultant score is more meaningful in precipitation deficit terms. • The monthly PHI score is then accumulated continuously. The possibility for the SPI to fluctuate from negative to positive or vice-versa within a time period can disguise the continuing presence of a significant hydrological drought or flood hazard. Continuous accounting of the PHI arguably provides greater insight into the potential onset, severity and duration of a significant hydrological event.

  7. SMAD pathway mediation of BDNF and TGFβ2 regulation of proliferation and differentiation of hippocampal granule neurons

    OpenAIRE

    Lu, J.; Wu, Y.; Sousa, Nuno; Almeida, O F X

    2005-01-01

    Hippocampal granule cells self-renew throughout life, whereas their cerebellar counterparts become post-mitotic during early postnatal development, suggesting that locally acting, tissue-specific factors may regulate the proliferative potential of each cell type. Confirming this, we show that conditioned medium from hippocampal cells (CMHippocampus) stimulates proliferation in cerebellar cultures and, vice versa, that mitosis in hippocampal cells is inhibited by CMCere...

  8. Risk analysis for privacy and identity management

    OpenAIRE

    Wangen, Gaute Bjørklund

    2012-01-01

    ENGELSK: The concept of privacy was recognized as early as the time of Aristotle, and has been a theme of debate since. Risks to privacy are problematic because the concept of "privacy" holds different meaning and importance to different people and cultures. What is considered private in Europe, may not be considered private in China, and vice versa. This makes defining and detecting risks to privacy a complex matter. As people become increasingly dependent on online services, ...

  9. Predicting the Alpha Comae Berenices Time of Eclipse: How 3 Ambiguous Measurements Out of 609 Caused a 26 Year Binary’s Eclipse to be Missed

    Science.gov (United States)

    2015-11-01

    PREDICTING THE α COMAE BERENICES TIME OF ECLIPSE: HOW 3 AMBIGUOUS MEASUREMENTS OUT OF 609 CAUSED A 26 YEAR BINARY’S ECLIPSE TO BE MISSED Matthew W...The dwarf stars in the 26 year period binary α Com were predicted to eclipse each other in early 2015. That prediction was based on an orbit model...to those with 12° or vice- versa. The stars are nearly equal magnitude, making such mistakes understandable (Struve 1875). While efforts were made to

  10. Le Tartuffe de MOLIÈRE L'emploi de la comédie est de corriger les vices des hommes (préface du Tartuffe Molière (1622- 1673

    Directory of Open Access Journals (Sweden)

    Perica Domijan

    2013-07-01

    Full Text Available Le 17 février 2013 il y avait 340 ans de la mort de Jean Baptiste Poquelin, dit Molière, un des plus grands auteurs comiques de notre époque. Il a renouvelé le genre de la comédie et créé des chefs-d'oœuvre qui depuis le XVIIe siècle n'ont jamais quitté la scène. Il a peint des caractères, des êtres profondément humains, remplaçant les types conventionnels des comédies antérieurs, et il a représenté avec précisions les mœurs de son temps. Avec sa comédie Tartouffe ou l'Hypocrite, Molière se heurta à ses ennemis les plus impitoyables. Il voulait s'attaquer à la Compagnie du Saint-Sacrement dont quelques membres, fanatiques ou fripons, semaient les désordres dans les familles sous prétexte d'en réformer les mœurs. La pièces fut interdite et ensuite refaite plusieurs fois. Alors, Le Tartuffe, que l'on s'accorde généralement à compter parmi les chefs-d'œuvre de Molière, n'a pourtant pas manqué d'être critiqué. Le présent article entreprend de décrire les effets du thème choisi par Molière: il ne manque pas d'hypocrites dans la littérature avant et après lui. S'il est difficile de préciser les intentions de Molière on peut néanmoins tenter de dégager le sens et la portée de la pièce et voir comment et pourquoi ce thème peut-être actuel et intriguant même au théâtre d'aujourd'hui. Molière a dit que l'emploi de la comédie est de corriger les vices des hommes. Jean-Jacques Rousseau lui reproche au contraire de favoriser les vices et de ne s'en prendre qu'aux ridicules. Il a beau jeu de dénoncer l'immoralité des personnages de Molière si on les juge individuellement, dans l'absolu. Mais ces personnages vivent en société: les déplorables effets sociaux de leurs vices et leur châtiment n'ont-ils aucune portée morale?

  11. Le Tartuffe de MOLIÈRE L'emploi de la comédie est de corriger les vices des hommes (préface du Tartuffe Molière (1622- 1673

    Directory of Open Access Journals (Sweden)

    Perica Domijan

    2013-07-01

    Full Text Available Le 17 février 2013 il y avait 340 ans de la mort de Jean Baptiste Poquelin, dit Molière, un des plus grands auteurs comiques de notre époque. Il a renouvelé le genre de la comédie et créé des chefs-d'oœuvre qui depuis le XVIIe siècle n'ont jamais quitté la scène. Il a peint des caractères, des êtres profondément humains, remplaçant les types conventionnels des comédies antérieurs, et il a représenté avec précisions les mœurs de son temps. Avec sa comédie Tartouffe ou l'Hypocrite, Molière se heurta à ses ennemis les plus impitoyables. Il voulait s'attaquer à la Compagnie du Saint-Sacrement dont quelques membres, fanatiques ou fripons, semaient les désordres dans les familles sous prétexte d'en réformer les mœurs. La pièces fut interdite et ensuite refaite plusieurs fois. Alors, Le Tartuffe, que l'on s'accorde généralement à compter parmi les chefs-d'œuvre de Molière, n'a pourtant pas manqué d'être critiqué. Le présent article entreprend de décrire les effets du thème choisi par Molière: il ne manque pas d'hypocrites dans la littérature avant et après lui. S'il est difficile de préciser les intentions de Molière on peut néanmoins tenter de dégager le sens et la portée de la pièce et voir comment et pourquoi ce thème peut-être actuel et intriguant même au théâtre d'aujourd'hui. Molière a dit que l'emploi de la comédie est de corriger les vices des hommes. Jean-Jacques Rousseau lui reproche au contraire de favoriser les vices et de ne s'en prendre qu'aux ridicules. Il a beau jeu de dénoncer l'immoralité des personnages de Molière si on les juge individuellement, dans l'absolu. Mais ces personnages vivent en société: les déplorables effets sociaux de leurs vices et leur châtiment n'ont-ils aucune portée morale? 

  12. ASPIRING VICE-CHANCELLORS' RHETORIC AND THE ...

    African Journals Online (AJOL)

    between thoughts or concepts and things), we take a discourse approach which treats language as opaque by engaging in an analysis of both the linguistic practices and the language of enquiry itself. Against this backdrop, we try to deconstruct the meaning of the rhetorical garbs of the campaign discourse of the aspirants ...

  13. Intervista Roberto Battiston, vice-portavoce AMS

    CERN Multimedia

    CERN Video Productions

    2011-01-01

    "L'universo è un'acceleratore di raggi cosmici che non è mai in shut down!"Commento sulla prima fase di funzionamento di AMS, a due mesi dal lancio nello spazio e dall'installazione sulla Stazione Spaziale Internazionale, con un flusso ininterrotto di dati: 100 milioni di trigger alla settimana.(2'19) Rest of video: rushes of the AMS POCC (Payload and Operations Control Centre) at CERN - Prevessin site.

  14. Vice Admiral Samuel Gravely: Leadership by Example

    Science.gov (United States)

    1998-04-01

    his leadership philosophy. They are: impression management , caretaker, pursuit of excellence, self-confidence, communication, team building...of Themes Inherent in VADM Gravely’s Leadership Philosophy. 1. Impression Management “I tried to set a record of perfect conduct ashore and at sea...superiors viewed you as a leader at different times in your career? 5. What were your strongest and weakest leadership traits at different times in your

  15. Dr Andrea Granelli, Vice President, Telecom Italia

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Photo 06: Dr Andrea Granelli, Chief Executive Officer, Telecom Italia Lab (second from right) visiting the LHC superconducting magnet test hall with (from left to right) M. Cecchi , F. Gagliardi and G. Cavallari. Photo 15: Dr Andrea Granelli, Chief Executive Officer, Telecom Italia Lab (left) visiting the LHC superconducting magnet test hall with (from left to right) M. Cecchi and G. Cavallari.

  16. 5 avril 2016 - J.-C. Marcourt Vice-Président blege du Gouvernement wallon, Ministre de l'Economie, de l'Industrie, de l'Innovation et du Numérique & Vice-Président du Gouvernement de la Fédération Wallonie-Bruxelles, Ministre de l'Enseignement supérieur, de la Recherche et des Médias signe le livre d'or avec le Directeur de la Recherche et du Calcul scientifique E. Elsen; Le chef du département IT F. Hemmer et le chef de la section TE-MSC-CMI J.-P. Tock sont également présents.

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2016-01-01

    Monsieur Jean-Claude Marcourt Vice-Président du Gouvernement wallon, Ministre de l'Economie, de l'Industrie, de l'Innovation et du Numérique Vice-Président du Gouvernement de la Fédération Wallonie-Bruxelles, Ministre de l'Enseignement supérieur, de la Recherche et des Médias

  17. 21 June 2010 - TUBITAK Vice President A. Adli signing the guest book with CERN Director-General R. Heuer, visiting the ATLAS control room at Point 1 with Former Collaboration Spokesperson P. Jenni and CMS Control Centre, building 354, with Collaboration Spokesperson G. Tonelli. Throughout accompanied by Adviser J. Ellis.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    21 June 2010 - TUBITAK Vice President A. Adli signing the guest book with CERN Director-General R. Heuer, visiting the ATLAS control room at Point 1 with Former Collaboration Spokesperson P. Jenni and CMS Control Centre, building 354, with Collaboration Spokesperson G. Tonelli. Throughout accompanied by Adviser J. Ellis.

  18. Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

  19. 6 March 2013 - Committee for Employment and Learning, Northern Ireland Legislative Assembly, United Kingdom of Great Britain and Northern Ireland in the LHC tunnel and visiting the LHCb experiment at LHC Point 8. Director for Accelerators and Technology S. Myers with Vice-Chair T. Buchanan.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    6 March 2013 - Committee for Employment and Learning, Northern Ireland Legislative Assembly, United Kingdom of Great Britain and Northern Ireland in the LHC tunnel and visiting the LHCb experiment at LHC Point 8. Director for Accelerators and Technology S. Myers with Vice-Chair T. Buchanan.

  20. Monsieur Etienne Blanc Premier vice-président de la Région Auvergne-Rhône-Alpes Délégué aux finances, à l'administration générale, aux économies budgétaires et aux politiques transfrontalières

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2017-01-01

    Monsieur Etienne Blanc Premier vice-président de la Région Auvergne-Rhône-Alpes Délégué aux finances, à l'administration générale, aux économies budgétaires et aux politiques transfrontalières

  1. 17 January 2014 - Y. Sakurada Japanese Senior Vice Minister of Education, Culture, Sports, Science and Technology signing the Guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez. Head of International Relations R. Voss present throughout.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    17 January 2014 - Y. Sakurada Japanese Senior Vice Minister of Education, Culture, Sports, Science and Technology signing the Guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez. Head of International Relations R. Voss present throughout.

  2. 19 January 2011 - Korean Vice Minister II of Education, Science and Technology K.Chang-Kyung with Adviser R. Voss, Director-General R. Heuer and head of International Relations F. Pauss; in the LHC tunnel at Point 5 and CMS experimental cavern with Collaboration Spokesperson G. Tonelli.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Korean vice-minister II of education, science and technology, Kim Chang-Kyung, visiting the CMS experimental area at CERN on 19 January. He also had the opportunity to view part of the LHC tunnel, as well as to visit the CERN Control Centre.

  3. 31st August 2011 - Government of Japan R. Chubachi, Executive Member of the Council for Science and Technology Policy, Cabinet Office, Vice Chairman, Representative Corporate Executive Officer and Member of the Board, Sony Corporation, visiting the ATLAS experimental area with Former Collaboration Spokesperson P. Jenni and Senior physicist T. Kondo.

    CERN Multimedia

    Raphaël Piguet

    2011-01-01

    31st August 2011 - Government of Japan R. Chubachi, Executive Member of the Council for Science and Technology Policy, Cabinet Office, Vice Chairman, Representative Corporate Executive Officer and Member of the Board, Sony Corporation, visiting the ATLAS experimental area with Former Collaboration Spokesperson P. Jenni and Senior physicist T. Kondo.

  4. 19th February 2010: Uppsala University Vice Chancellor A. Hallberg signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci (right) and Uppsala University Professor of Elementary Particle Physics and Chairman of the Swedish LHC Consortium T. Ekelöf.

    CERN Multimedia

    Jean-Claude Gadmer

    2010-01-01

    Other members of the Uppsala University delegation: Vice Rector J.Nordgren; Director A. Fust and Physics Faculty Dean U. Danielsson. Visiting the Superconducting magnet test hall and CTF3 Facility with CLIC Collaboration and Uppsala University R. Ruber; in the ATLAS visitor centre with Collaboration Resources Manager M. Nordberg.

  5. 24 January 2012 - British Vice-Chancellor of the University of Cambridge Sir Leszek Borysiewicz signing the guest book with CERN Director-General, visiting ATLAS experimental area with Collaboration Deputy Spokesperson D. Charlton and Sm18 with engineer R. Veness.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    24 January 2012 - British Vice-Chancellor of the University of Cambridge Sir Leszek Borysiewicz signing the guest book with CERN Director-General, visiting ATLAS experimental area with Collaboration Deputy Spokesperson D. Charlton and Sm18 with engineer R. Veness.

  6. 2nd September 2010 - Japanese Senior Vice-Minister of the Environment I. Tajima signing the guest book with Director-General R. Heuer and visiting the ATLAS control room with physicists T. Kondo and H. Fukuda, Members of the ATLAS Collaboration and KEK.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    2nd September 2010 - Japanese Senior Vice-Minister of the Environment I. Tajima signing the guest book with Director-General R. Heuer and visiting the ATLAS control room with physicists T. Kondo and H. Fukuda, Members of the ATLAS Collaboration and KEK.

  7. 21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

    CERN Multimedia

    Claudia Marcelloni

    2008-01-01

    21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

  8. 1st September 2010 - British Vice-Chancellor, Liverpool University Sir Newby and Lady Newby signing the Guest Book with Head of International Relations F. Pauss; visiting the LHC superconducting magnet test hall with P. Cruikshank; accompanied by Beams Department Head P. Collier and Liverpool University T. Bowcock and P. Allport.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    1st September 2010 - British Vice-Chancellor, Liverpool University Sir Newby and Lady Newby signing the Guest Book with Head of International Relations F. Pauss; visiting the LHC superconducting magnet test hall with P. Cruikshank; accompanied by Beams Department Head P. Collier and Liverpool University T. Bowcock and P. Allport.

  9. 23rd May 2011 - University of Liverpool Pro-Vice-Chancellor and Public Orator K. Everest (UK) Mrs Everest in the ATLAS visitor centre with Collaboration Deputy Spokesperson D. Charlton, in LHCb surface building with Collaboration Spokesperson A. Golutvin, accompanied throughout by P. Wells and Liverpool University T. Bowcock and M. Klein.

    CERN Multimedia

    Maximilen Brice

    2011-01-01

    23rd May 2011 - University of Liverpool Pro-Vice-Chancellor and Public Orator K. Everest (UK) Mrs Everest in the ATLAS visitor centre with Collaboration Deputy Spokesperson D. Charlton, in LHCb surface building with Collaboration Spokesperson A. Golutvin, accompanied throughout by P. Wells and Liverpool University T. Bowcock and M. Klein.

  10. 30 January 2012 - Ecuadorian Ambassador Gallegos Chiriboga, Permanent Representative to the United Nations Office and other International Organisations at Geneva and San Francisco de Quito University Vice Chancellor C. Montùfar visiting CMS surface facilities and underground experimental area with CMS Collaboration L. Sulak and Collaboration Deputy Spokesperson T. Camporesi, throughout accompanied by Head of International Relations F. Pauss.

    CERN Multimedia

    Michael Hoch

    2012-01-01

    30 January 2012 - Ecuadorian Ambassador Gallegos Chiriboga, Permanent Representative to the United Nations Office and other International Organisations at Geneva and San Francisco de Quito University Vice Chancellor C. Montùfar visiting CMS surface facilities and underground experimental area with CMS Collaboration L. Sulak and Collaboration Deputy Spokesperson T. Camporesi, throughout accompanied by Head of International Relations F. Pauss.

  11. 15 January 2010 - Vice-Chancellor & Chief Executive C. Snowden, University of Surrey, United Kingdom and Mrs Snowden visiting ALICE exhibition and experimental undeground area with Collabortion Spokesperson J. Schukraft and Beams Department Head P. Collier; Signature of the guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    15 January 2010 - Vice-Chancellor & Chief Executive C. Snowden, University of Surrey, United Kingdom and Mrs Snowden visiting ALICE exhibition and experimental undeground area with Collabortion Spokesperson J. Schukraft and Beams Department Head P. Collier; Signature of the guest book with CERN Director-General R. Heuer.

  12. 16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

  13. 11 July 2011 - Carleton University Ottawa, Canada Vice President (Research and International) K. Matheson in the ATLAS visitor centre with Collaboration Spokesperson F. Gianotti, accompanied by Adviser J. Ellis and signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci.

    CERN Multimedia

    Jean-Claude Gadmer

    2011-01-01

    11 July 2011 - Carleton University Ottawa, Canada Vice President (Research and International) K. Matheson in the ATLAS visitor centre with Collaboration Spokesperson F. Gianotti, accompanied by Adviser J. Ellis and signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci.

  14. 30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

  15. 17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

  16. 19 April 2013 - The University of Chicago Vice President for Research and for National Laboratories D. H. Levy signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the LHC tunnel with L. Bottura; throughout accompanied by US CMS J. Butler. Mrs Levy and Mrs Butler took part.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    19 April 2013 - The University of Chicago Vice President for Research and for National Laboratories D. H. Levy signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the LHC tunnel with L. Bottura; throughout accompanied by US CMS J. Butler. Mrs Levy and Mrs Butler took part.

  17. 27 November 2014 - Warsaw University of Technology (PL) Vice-Rector for Research R. Bacewicz visitng the ALICE control room and undergorund experimental area with WUT students, accompanied by A. Charkiewicz and A. Siemko; joint signature ceremony with HNINP Director-General M. Jezabek

    CERN Multimedia

    Guillaume, Jeanneret

    2014-01-01

    CERN-PHOTO-201411-245-95: from left to right: Professor D.Sc.Ph.D. Rajmund Bacewicz, Vice-Rector for Research, Warsaw University of Technology, CERN Director-General R. Heuer and Prof. Marek Jeżabek, Director-General, Henryk Niewodniczanski Institute of Nuclear Physics, Republic of Poland

  18. Yeast Interacting Proteins Database: YMR047C, YDR229W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available , may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach...s33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase Rows with this p

  19. 41 CFR 105-57.002 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... not limited to, salary, bonuses, commissions, and vacation pay) from an employer remaining after the...) Employer means a person or entity that employs the services of others and that pays their wages or salaries... vice versa, and words signifying the masculine gender shall include the feminine and vice versa. The...

  20. Probing the molecules of the mind

    African Journals Online (AJOL)

    Adele

    2005-01-10

    Jan 10, 2005 ... A forms hydrogen bonds specifically with T and vice versa, while G forms hydrogen bonds specifically with C and vice versa. In this way each strand of DNA is strongly bound through specific hydrogen bonds to its complementary strand ..... a catalogue of car parts of itself is of little use to the motor mechanic ...

  1. Autism: Why Act Early?

    Science.gov (United States)

    ... this? Submit What's this? Submit Button Past Emails Autism: Why Act Early? Language: English (US) Español (Spanish) ... helped the world make sense." Florida teenager with Autism Spectrum Disorder "Because my parents acted early, I ...

  2. Gender and Early Warning

    OpenAIRE

    Schmeidl, Susanne

    2016-01-01

    This paper argues that the introduction of gender into early warning will lead to more practical, realistic and usable early warning approaches, especially if early warning is understood as a flexible system that is sensitive to the diverse situations or on the ground necessitating customised solution. A gender-sensitive approach can enhance early warning models in their basic assumption (what we consider as important or not and the questions we are asking), in their modelling (incorporating ...

  3. Early rehabilitation after stroke

    OpenAIRE

    Bernhardt, Julie; Godeckeb, Erin; Johnson, Liam; Langhorne, Peter

    2017-01-01

    Purpose of review: \\ud Early rehabilitation is recommended in many guidelines, with limited evidence to guide practice. Brain\\ud neurobiology suggests that early training, at the right dose, will aid recovery. In this review, we highlight\\ud recent trials of early mobilization, aphasia, dysphagia and upper limb treatment in which intervention is\\ud commenced within 7 days of stroke and discuss future research directions.\\ud Recent findings: \\ud Trials in this early time window are few. Althou...

  4. La Création du Vice Secrétariat de l’Education Populaire La creación de la Vicesecretaría de Educación Popular The creation of Vicesecretaría de Educación Popular

    Directory of Open Access Journals (Sweden)

    Marie-Aline Barrachina

    2009-01-01

    Full Text Available La creación (20-05-1941, de la Vice Secretaría de la Educación Popular, pone un punto final a las ambiciones totalitarias de los falangistas, marca su  definitiva derrota y la ineluctable instrumentalización de sus talentos propagandísticos. El proceso se realiza en tres etapas: desde el decreto de Unificación (19-04-1937, hasta el primer gobierno civil del régimen de Franco (31-01-1938; desde este mismo primer gobierno civil hasta la consolidación de la influencia de Serrano Súnyer (16-11-1940, acceso de Serrano a la cartera de relaciones internacionales; por fin, desde esta fecha, a la creación de la Vice Secretaría. El proceso consistió en externalizar las competencias intelectuales falangistas en un primer tiempo, de manera que no puedan actuar dentro de la administración del Movimiento sino directamente bajo el control del Estado (1937. Luego, en una segunda etapa, se instrumentalizaron estas competencias para organizar las estructuras administrativas de propaganda del nuevo Estado (1938-1940. Por fin, cuando ya estaba confirmada su total sumisión (1941, se devolvió a la administración del Movimiento su vocación inicial de propaganda, creando la Vice Secretaría. A finales de 1943, la Vice Secretaría ya es una enorme máquina administrativa generadora de empleos y sometida al Estado. Su traspaso en 1945 al Ministerio de la Educación — entonces entre las manos de los conservadores católicos— confirma que la era de los funcionarios del franquismo ya se ha sustituido a la de los militantes falangistas.

  5. Early juvenile idiopathic arthritis.

    Science.gov (United States)

    Marzan, Katherine Anne B; Shaham, Bracha

    2012-05-01

    Early juvenile idiopathic arthritis (JIA) is important to recognize as timely diagnosis and treatment improves prognosis. It is a misconception that complications of JIA arise only from long-standing disease and that children will outgrow it. Early aggressive treatment is the paradigm as early disease activity has long-term consequences. There are predictors of persistent disease and joint erosions that may identify patients at higher risk. Control of disease activity within the first 6 months of onset confers improved clinical course and outcomes. The treatment perspective is thus one of early aggressive treatment for induction of disease control and ultimately remission. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Jamaica on Early Maps.

    Science.gov (United States)

    Richason, Benjamin F., Jr.

    1983-01-01

    Columbus sighted Jamaica during his second voyage and was marooned there for more than a year during his fourth. The succession of early maps of Jamaica betrays its slow development and its unimportance to early colonizers. Modern tourism is the elusive "gold" which the Spanish fortune hunters did not find. (CS)

  7. Early detection of psychosis

    DEFF Research Database (Denmark)

    Larsen, T. K.; Melle, I.; Auestad, B.

    2011-01-01

    Background During the last decades we have seen a new focus on early treatment of psychosis. Several reviews have shown that duration of untreated psychosis (DUP) is correlated to better outcome. However, it is still unknown whether early treatment will lead to a better long-term outcome. This st...

  8. Early College High Schools

    Science.gov (United States)

    Dessoff, Alan

    2011-01-01

    For at-risk students who stand little chance of going to college, or even finishing high school, a growing number of districts have found a solution: Give them an early start in college while they still are in high school. The early college high school (ECHS) movement that began with funding from the Bill and Melinda Gates Foundation 10 years ago…

  9. Waterford Early Reading Program.

    Science.gov (United States)

    Education Commission of the States, Denver, CO.

    This paper provides an overview of the Waterford Early Reading Program (WERP), which is designed to shift teaching and learning away from remediation and failure to prevention, early achievement, and sustained growth for every student. WERP includes three levels of instruction: emergent, beginning, and fluent readers. It targets pre-K through…

  10. Rethinking Early Education

    Science.gov (United States)

    Celeste, Eric

    2017-01-01

    The National Association for the Education of Young Children (NAEYC) says in its current policy paper that, for high-quality early education to exist outside of tiny islands across the country, the following must be addressed: (1) teacher preparation; (2) ongoing professional learning; and (3) disparity in early education teacher pay. To achieve…

  11. Early Option Exercise

    DEFF Research Database (Denmark)

    Jensen, Mads Vestergaard; Heje Pedersen, Lasse

    2016-01-01

    A classic result by Merton (1973) is that, except just before expiration or dividend payments, one should never exercise a call option and never convert a convertible bond. We show theoretically that this result is overturned when investors face frictions. Early option exercise can be optimal when...... it reduces short-sale costs, transaction costs, or funding costs. We provide consistent empirical evidence, documenting billions of dollars of early exercise for options and convertible bonds using unique data on actual exercise decisions and frictions. Our model can explain as much as 98% of early exercises...

  12. Early Life Stages

    Science.gov (United States)

    Childhood should be viewed as a sequence of lifestages, from birth through infancy and adolescence. When assessing early life risks, consideration is given to risks resulting from fetal exposure via the pregnant mother, as well as postnatal exposures.

  13. Early stage colon cancer

    National Research Council Canada - National Science Library

    Freeman, Hugh James

    2013-01-01

    .... After resection of malignant pedunculated colon polyps or early stage colon cancers, long-term repeated surveillance programs can also lead to detection and removal of asymptomatic high risk advanced...

  14. Tooth decay - early childhood

    Science.gov (United States)

    Bottle mouth; Bottle carries; Baby bottle tooth decay; Early childhood caries (ECC) ... inside of your baby's mouth healthy and prevents tooth decay. If you are bottle-feeding your baby: Give babies, ages newborn to ...

  15. Early warning scores.

    Science.gov (United States)

    2012-09-27

    A free app available from the Apple App Store is aimed at supporting health professionals in Wales to use the National Early Warning Score (NEWS). The tool helps staff identify patients who are developing serious illness.

  16. Early Head Start Evaluation

    Data.gov (United States)

    U.S. Department of Health & Human Services — Longitudinal information from an evaluation where children were randomly assigned to Early Head Start or community services as usual;direct assessments and...

  17. Overview of Early Intervention

    Science.gov (United States)

    ... eligible babies and toddlers learn the basic and brand-new skills that typically develop during the first ... Services in Natural Environments Transition to Preschool Public Awareness & the Referral System Early Intervention, Then and Now ...

  18. Guideline for Early Interventions

    National Research Council Canada - National Science Library

    Vries, de, Maaike

    2006-01-01

    .... During the last years, the demand for early interventions has been increasing. International literature has shown that the psychosocial effects of disaster and military deployment may last for years...

  19. Early-onset schizophrenia

    OpenAIRE

    Hojka Gregorič Kumperščak

    2013-01-01

    Early-onset schizophrenia is defined as schizophrenia with onset before the age of 18 years. While schizophrenia is a very rare disorder in childhood, it becomes increasingly common during adolescence and peaks in early adulthood. Even though childhood and adolescent schizophrenia lie on a continuum with adult schizophrenia and show roughly the same clinical picture, they both have some developmental specifics. They display greater symptom variability making the ...

  20. Embracing early literacy indicators

    DEFF Research Database (Denmark)

    Broström, Stig; Hansen, Ole Henrik; Jensen, Anders Skriver

    2010-01-01

    Abstract til paper om early literacy indikatorer. Det paper abstractet er knyttet til var en del af et inviteret, selvorganiseret symposium som afrapporterede EASE-projektet (www.ease-eu.com) på OMEP's 26. verdenskongres.......Abstract til paper om early literacy indikatorer. Det paper abstractet er knyttet til var en del af et inviteret, selvorganiseret symposium som afrapporterede EASE-projektet (www.ease-eu.com) på OMEP's 26. verdenskongres....

  1. Redefining early gastric cancer.

    Science.gov (United States)

    Barreto, Savio G; Windsor, John A

    2016-01-01

    The problem is that current definitions of early gastric cancer allow the inclusion of regional lymph node metastases. The increasing use of endoscopic submucosal dissection to treat early gastric cancer is a concern because regional lymph nodes are not addressed. The aim of the study was thus to critically evaluate current evidence with regard to tumour-specific factors associated with lymph node metastases in "early gastric cancer" to develop a more precise definition and improve clinical management. A systematic and comprehensive search of major reference databases (MEDLINE, EMBASE, PubMed and the Cochrane Library) was undertaken using a combination of text words "early gastric cancer", "lymph node metastasis", "factors", "endoscopy", "surgery", "lymphadenectomy" "mucosa", "submucosa", "lymphovascular invasion", "differentiated", "undifferentiated" and "ulcer". All available publications that described tumour-related factors associated with lymph node metastases in early gastric cancer were included. The initial search yielded 1494 studies, of which 42 studies were included in the final analysis. Over time, the definition of early gastric cancer has broadened and the indications for endoscopic treatment have widened. The mean frequency of lymph node metastases increased on the basis of depth of infiltration (mucosa 6% vs. submucosa 28%), presence of lymphovascular invasion (absence 9% vs. presence 53%), tumour differentiation (differentiated 13% vs. undifferentiated 34%) and macroscopic type (elevated 13% vs. flat 26%) and tumour diameter (≤2 cm 8% vs. >2 cm 25%). There is a need to re-examine the diagnosis and staging of early gastric cancer to ensure that patients with one or more identifiable risk factor for lymph node metastases are not denied appropriate chemotherapy and surgical resection.

  2. Early diagnosis of early stage lung cancer

    Directory of Open Access Journals (Sweden)

    Andrej Debeljak

    2005-11-01

    Full Text Available Background: For the detection of premalignant changes of bronchial mucosa and early stages of lung cancer frequent chest X-ray, spiral low dose computed tomography, fluorescence bronchoscopy, sputum cytology (also with automated systems with genetic and molecular changes in the sputum cells and bronchial mucosa were used. These screening methods of the high-risk groups for lung cancer achieved: earlier diagnosis of lung cancer in lower stage, higher operability, longer 5-year survival, but without mortality reduction.Conclusions: In the clinical practice we can examine higher risk groups for lung cancer in randomised control trials with multimodality approach: frequent chest low-dose fast spiral computed tomography, sputum cytology with genetic and molecular examinations and fluorescence bronchoscopy. Smoking cessation remains the best means to achieve mortality reduction from lung cancer.

  3. Introduction to "Early psychosis

    DEFF Research Database (Denmark)

    McGorry, Patrick; Nordentoft, Merete; Simonsen, Erik

    2005-01-01

    Early intervention in psychiatry has taken a long time to emerge as a key strategy to reduce morbidity and mortality. In other fields of medicine it has received consistent support and great efforts are expended to educate the public about the value of early diagnosis and the benefits of timely...... intervention. There is finally substantial momentum behind similar endeavours in psychotic disorders, which, now they have reached "proof of concept" stage, could begin to be extended across the spectrum of serious mental disorders. There is also ambivalence and resistance to this evidence-based reform which...

  4. Early Islamic Syria

    DEFF Research Database (Denmark)

    Walmsley, Alan

    After more than a century of neglect, a profound revolution is occurring in the way archaeology addresses and interprets developments in the social history of early Islamic Syria-Palestine. This concise book offers an innovative assessment of social and economic developments in Syria-Palestine...... for considerable cultural and economic continuity rather than devastation and unrelenting decline. Much new, and increasingly non-elite, architectural evidence and an ever-growing corpus of material culture indicate that Syria-Palestine entered a new age of social richness in the early Islamic period, even...

  5. Early life vaccination

    DEFF Research Database (Denmark)

    Nazerai, Loulieta; Bassi, Maria Rosaria; Uddbäck, Ida Elin Maria

    2016-01-01

    the first period of life and provide a pertinent alternative in infant vaccinology. To address this, infant mice were vaccinated with three different adenoviral vectors and the CD8+ T-cell response after early life vaccination was explored. We assessed the frequency, polyfunctionality and in vivo...... cytotoxicity of the elicited memory CD8+ T cells, as well as the potential of these cells to respond to secondary infections and confer protection. We further tested the impact of maternal immunity against our replication-deficient adenoviral vector during early life vaccination. Overall, our results indicate...

  6. 75 FR 20830 - Early Learning

    Science.gov (United States)

    2010-04-21

    ... Early Learning AGENCY: Office of the Secretary, Department of Education. ACTION: Notice of public..., is seeking input from State agencies responsible for early learning and development, families..., researchers of early learning, stakeholders who work with early learning and development for young children...

  7. Early Islamic Syria

    DEFF Research Database (Denmark)

    Walmsley, Alan George

    This book presents a new interpretation of social and economic developments in Syria-Palestine in the decades before and during the two centuries after the Islamic expansion into the region (roughly the later 6th to the early 9th century AD). Drawing on a wide range of evidence from recent archae...

  8. Creativity: The Early Years

    Science.gov (United States)

    Shade, Rick; Shade, Patti Garrett

    2016-01-01

    There is a myth that some people are creative and others are not. However, all children are born creative. They love to explore, ask questions, and are incredibly imaginative. Parents are key in nurturing their child's creativity in the early years. This article offers resources and strategies parents can use at different ages and stages (newborn,…

  9. Teaching polymorphism early

    DEFF Research Database (Denmark)

    2005-01-01

    Is it possible to teach dynamic polymorphism early? What techniques could facilitate teaching it in Java. This panel will bring together people who have considered this question and attempted to implement it in various ways, some more completely than others. It will also give participants...

  10. Early hominin auditory capacities.

    Science.gov (United States)

    Quam, Rolf; Martínez, Ignacio; Rosa, Manuel; Bonmatí, Alejandro; Lorenzo, Carlos; de Ruiter, Darryl J; Moggi-Cecchi, Jacopo; Conde Valverde, Mercedes; Jarabo, Pilar; Menter, Colin G; Thackeray, J Francis; Arsuaga, Juan Luis

    2015-09-01

    Studies of sensory capacities in past life forms have offered new insights into their adaptations and lifeways. Audition is particularly amenable to study in fossils because it is strongly related to physical properties that can be approached through their skeletal structures. We have studied the anatomy of the outer and middle ear in the early hominin taxa Australopithecus africanus and Paranthropus robustus and estimated their auditory capacities. Compared with chimpanzees, the early hominin taxa are derived toward modern humans in their slightly shorter and wider external auditory canal, smaller tympanic membrane, and lower malleus/incus lever ratio, but they remain primitive in the small size of their stapes footplate. Compared with chimpanzees, both early hominin taxa show a heightened sensitivity to frequencies between 1.5 and 3.5 kHz and an occupied band of maximum sensitivity that is shifted toward slightly higher frequencies. The results have implications for sensory ecology and communication, and suggest that the early hominin auditory pattern may have facilitated an increased emphasis on short-range vocal communication in open habitats.

  11. Prenatal depression: Early intervention.

    Science.gov (United States)

    Anderson, Cheryl A; Lieser, Carol

    2015-07-15

    Frequently undiagnosed and untreated, prenatal depression affects approximately one in four childbearing women. Screening and appropriate management is essential to prevent adverse consequences to both the woman and her unborn infant. Early conversations between the woman and her nurse practitioner are essential to making medical management decisions.

  12. Early Developments in Crystallography

    Indian Academy of Sciences (India)

    IAS Admin

    molecules to treat different diseases, make materials of desired properties and attempt to understand unknown territories far away from the Earth such as the exploration of the surface of. Mars. In this article, we will try to trace the early historical events in the development of X-ray crystallography, and the Indian contributions ...

  13. Early Mover Advantages

    NARCIS (Netherlands)

    G.E. Bijwaard (Govert); M.C.W. Janssen (Maarten); E. Maasland (Emiel)

    2004-01-01

    textabstractIn this paper we analyze empirically whether and if so to what extent later entrants in the European mobile telephony industry have a disadvantage vis-à-vis incumbents and early mover entrants. To analyze this question we consider a series of static models and a dynamic model of market

  14. Early Islamic Syria

    DEFF Research Database (Denmark)

    Walmsley, Alan George

    This book presents a new interpretation of social and economic developments in Syria-Palestine in the decades before and during the two centuries after the Islamic expansion into the region (roughly the later 6th to the early 9th century AD). Drawing on a wide range of evidence from recent...

  15. Early Childhood--Love

    Science.gov (United States)

    Jackson, Sylvia

    1976-01-01

    If children are to love themselves and others, they must experience love early. And they need to be taught the value of love, since it tends to fall victim to other lesser emotions. Provides suggestions for helping young children to grow in love. (Author/RK)

  16. Music in Early Childhood.

    Science.gov (United States)

    Feierabend, John

    1990-01-01

    Argues that music activities in early childhood education foster a variety of developmental skills. Analyzes Howard Gardner's theory of multiple intelligences, contending that music intelligence is a separate intelligence. Provides ways to identify and promote musical intelligence. Suggests methods for encouraging musical development. Using songs…

  17. Early hominin auditory capacities

    Science.gov (United States)

    Quam, Rolf; Martínez, Ignacio; Rosa, Manuel; Bonmatí, Alejandro; Lorenzo, Carlos; de Ruiter, Darryl J.; Moggi-Cecchi, Jacopo; Conde Valverde, Mercedes; Jarabo, Pilar; Menter, Colin G.; Thackeray, J. Francis; Arsuaga, Juan Luis

    2015-01-01

    Studies of sensory capacities in past life forms have offered new insights into their adaptations and lifeways. Audition is particularly amenable to study in fossils because it is strongly related to physical properties that can be approached through their skeletal structures. We have studied the anatomy of the outer and middle ear in the early hominin taxa Australopithecus africanus and Paranthropus robustus and estimated their auditory capacities. Compared with chimpanzees, the early hominin taxa are derived toward modern humans in their slightly shorter and wider external auditory canal, smaller tympanic membrane, and lower malleus/incus lever ratio, but they remain primitive in the small size of their stapes footplate. Compared with chimpanzees, both early hominin taxa show a heightened sensitivity to frequencies between 1.5 and 3.5 kHz and an occupied band of maximum sensitivity that is shifted toward slightly higher frequencies. The results have implications for sensory ecology and communication, and suggest that the early hominin auditory pattern may have facilitated an increased emphasis on short-range vocal communication in open habitats. PMID:26601261

  18. Early childhood aggression

    NARCIS (Netherlands)

    Alink, Lenneke Rosalie Agnes

    2006-01-01

    In this thesis the development, stability, and correlates of early childhood aggression were investigated. The normative development was examined in a general population sample using questionnaires completed by the parents of 12-, 24-, and 36-month-old children and again one year later. Results

  19. Early Childhood Trauma

    Science.gov (United States)

    National Child Traumatic Stress Network, 2010

    2010-01-01

    Early childhood trauma generally refers to the traumatic experiences that occur to children aged 0-6. Because infants' and young children's reactions may be different from older children's, and because they may not be able to verbalize their reactions to threatening or dangerous events, many people assume that young age protects children from the…

  20. Early Option Exercise

    DEFF Research Database (Denmark)

    Heje Pedersen, Lasse; Jensen, Mads Vestergaard

    A classic result by Merton (1973) is that, except just before expiration or dividend payments, one should never exercise a call option and never convert a convertible bond. We show theoretically that this result is overturned when investors face frictions. Early option exercise can be optimal whe...

  1. Early intervention in psychosis

    DEFF Research Database (Denmark)

    Csillag, Claudio; Nordentoft, Merete; Mizuno, Masafumi

    2017-01-01

    AIM: Early intervention in psychosis (EIP) is a well-established approach with the intention of early detection and treatment of psychotic disorders. Its clinical and economic benefits are well documented. This paper presents basic aspects of EIP services, discusses challenges to their implementa......AIM: Early intervention in psychosis (EIP) is a well-established approach with the intention of early detection and treatment of psychotic disorders. Its clinical and economic benefits are well documented. This paper presents basic aspects of EIP services, discusses challenges...... implemented EIP services into the mental healthcare system have generated evidence, concepts and specific strategies that might serve as guidance or inspiration in other countries or systems where EIP is less well developed or not developed at all. Previous experience has made clear that evidence of clinical...... benefits alone is not enough to promote implementation, as economic arguments and political and social pressure have shown to be important elements in efforts to achieve implementation. CONCLUSIONS: Users' narratives, close collaboration with community organizations and support from policy-makers and known...

  2. Two Pontic rivers

    DEFF Research Database (Denmark)

    Bekker-Nielsen, Tønnes; Jensen, Marit

    2015-01-01

    The accounts of the landscape around the Iris (Yeşilirmak) and the Thermodon (Terme) given by ancient authors are diverse and often contradictory. The Periegesis of the World by Dionysius of Alexandria, a didactic poem written in the early IInd c. A.D., established an image of the two rivers...... that does not correspond to their actual characteristics. A closer study reveals that Dionysius, or possibly his source, has confused the two: the river which he describes as the Thermodon is in fact the Iris, and vice versa. This mistake was not realized by later translators (Avienus, late IVth c. A...

  3. Electrochemical Science and Technology

    CERN Document Server

    Oldham, Keith; Bond, Alan

    2011-01-01

    The book addresses the scientific principles underlying electrochemistry. Starting with the basic concepts of electricity, the early chapters discuss the physics and chemistry of the materials from which electrochemical cells are constructed and the properties that make these materials appropriate as cell components. Much of the importance of electrochemistry lies in the conversion of electrical energy into chemical energy and vice versa; the thermodynamics of these processes is described, in the context of a wide range of applications of these interconversions. An electrode is a surface at wh

  4. An Extensional Characterization of Lambda-Lifting and Lambda-Dropping

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1999-01-01

    Lambda-lifting and lambda-dropping respectively transform a block-structured functional program into recursive equations and vice versa. Lambda-lifting was developed in the early 80’s, whereas lambda-dropping is more recent. Both are split into an analysis and a transformation. Published work......, however, has only concentrated on the analysis parts. We focus here on the transformation parts and more precisely on their correctness, which appears never to have been proven. To this end, we define extensional versions of lambda-lifting and lambda-dropping and establish their correctness with respect...

  5. An Extensional Characterization of Lambda-Lifting and Lambda-Dropping

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Lambda-lifting and lambda-dropping respectively transform a block-structured functional program into recursive equations and vice versa. Lambda-lifting was developed in the early 80’s, whereas lambda-dropping is more recent. Both are split into an analysis and a transformation. Published work......, however, has only concentrated on the analysis parts. We focus here on the transformation parts and more precisely on their correctness, which appears never to have been proven. To this end, we define extensional versions of lambda-lifting and lambda-dropping and establish their correctness with respect...

  6. Switching between intravenous and subcutaneous trastuzumab

    DEFF Research Database (Denmark)

    Gligorov, Joseph; Curigliano, Giuseppe; Müller, Volkmar

    2017-01-01

    AIM: To assess the safety and tolerability of switching between subcutaneous (SC) and intravenous (IV) trastuzumab in the PrefHer study (NCT01401166). PATIENTS AND METHODS: Patients with HER2-positive early breast cancer completed (neo)adjuvant chemotherapy and were randomised to receive four....... Rates of clinically important events, including grade ≥3 AEs, serious AEs, AEs leading to study drug discontinuation and cardiac AEs, were low and similar between treatment arms (safety signals for trastuzumab were observed. CONCLUSIONS: PrefHer revealed...... that switching from IV to SC trastuzumab (hand-held syringe or SID) or vice versa did not impact the known safety profile of trastuzumab....

  7. Early Years Policy

    Directory of Open Access Journals (Sweden)

    Jane Waldfogel

    2011-01-01

    Full Text Available We analyze the role that early years policy might play in narrowing educational attainment gaps. We begin by examining gaps in school readiness between low-, middle-, and high-income children, drawing on data from new large and nationally representative birth cohort studies in the USA and UK. We find that sizable income-related gaps in school readiness are present in both countries before children enter school and then decompose these gaps to identify the factors that account for the poorer scores of low-income children. We then consider what role early years policy could play in tackling these gaps, drawing on the best available evidence to identify promising programs.

  8. Samuel Goudsmit - Early Influences

    Science.gov (United States)

    Goudsmit, Esther

    2010-03-01

    Samuel Goudsmit, born in 1902 in The Hague, Netherlands, earned his Ph.D. at the University of Leiden in 1926 with Paul Ehrenfest. The present talk will describe some aspects of his background and early formative years in order to provide context for the broad range of his professional life. Sam belonged to a large tribe of paternal and maternal uncles, aunts and first cousins; including his parents, grandparents and sister Ro, they numbered forty. Sam was the first of the tribe to be educated beyond high school. Early interests as a child and later as a university student in the Netherlands prefigured his significant and diverse contributions in several realms including not only physics but also teaching, Egyptology and scientific Intelligence. Bibliographic sources will include: The American Institute of Physics' Oral History Transcripts and photographs from the Emilio Segre visual archives, memoirs and conversations of those who knew Sam and also letters to his daughter, Esther.

  9. Early Permian bipedal reptile.

    Science.gov (United States)

    Berman, D S; Reisz, R R; Scott, D; Henrici, A C; Sumida, S S; Martens, T

    2000-11-03

    A 290-million-year-old reptilian skeleton from the Lower Permian (Asselian) of Germany provides evidence of abilities for cursorial bipedal locomotion, employing a parasagittal digitigrade posture. The skeleton is of a small bolosaurid, Eudibamus cursoris, gen. et sp. nov. and confirms the widespread distribution of Bolosauridae across Laurasia during this early stage of amniote evolution. E. cursoris is the oldest known representative of Parareptilia, a major clade of reptiles.

  10. Early Detection Of Cancer

    Directory of Open Access Journals (Sweden)

    V B Bhatnagar

    1987-04-01

    Full Text Available Farly detection of cancer is based upon three fundamental assumptions, firstly that the trea'ment of benign and precancerous lesions reduces the incidence of cancer, secondly, that the treatment of in situ cancers is conducive to total cure and thirdly that early diagnosis and management of invasive cancer ensures be.ter survival. When patient seeks medical advice for vague symptoms, which could however be due to a possible malignant tumour at a particular site, the alert clinician should investigate the patient immediately to exclude cancer. At this stage cancer is usually not significantly advanced.Currently the U. I. C. C. (International Union for Cancer Control} is studying the epidemiology of cancers in various countries The importance of this is two folds : Firstly by focussing attention on a section of population vulnerable to a particular cancer an early detection is facilitated Secondly by changing the causative factors responsible to a particular cancer, the incidence of that cancer can be reduced e. g. reduction in lung cancer following campaigns against ciguette smoking and reductioi in breast cancer after campaigns for advocating breast feeding of infants, lowering fat consumption and encouraging self palpation of breast regularly.Indeed early diagnosis of cancer implies diagnosis of cancer in almost a symptomatic stage It involves motiva’ion of the population towards acquisitio : of knowledge, attitude and practice.. Epidemiologies and clinicians should be able to recognise high risk cases exposed to particular neoplasia and knowledge of alarming symptoms should be pro- pogated for wide publicity through common available media and means. Probable cases should have regular clhrcal examination periodically and relevant investigations including radiological, imaging techniques and Bio-Chemical examination should be undertaken as and when desired Suspicious lesions should be investigated by specific tests including smear cytology

  11. Early prevention of obesity

    OpenAIRE

    Claudio Maffeis

    2014-01-01

    Childhood obesity is the metabolic disorder with the highest prevalence in both children and adults. Urgency to treat and prevent childhood obesity is based on the clear evidence that obesity tends to track from childhood to adulthood, is associated to morbidity also in childhood and to long-term mortality. Early life, i.e., intrauterine life and the first two years, is a sensitive window for prevention. Anatomical and functional maturation of the hypothalamic structures devoted to regulating...

  12. Early Building Design

    DEFF Research Database (Denmark)

    Østergård, Torben; Jensen, Rasmus Lund; Maagaard, Steffen

    2017-01-01

    Highlights •Development of a design methodology that can handle the vast design space in early building design. •A global design space is modelled from extensive Monte Carlo simulations. •Sensitivity analysis methods applied to guide decision-makers. •Interactive visualizations help the multi......-actor design team explore thousands of building performance simulations. •Metamodels are used to run additional simulations and demonstrate the holistic consequences of input changes....

  13. Coaching in Early Mathematics.

    Science.gov (United States)

    Germeroth, Carrie; Sarama, Julie

    2017-01-01

    Falling scores in math have prompted a renewed interest in math instruction at early ages. By their own admission, early childhood educators are generally underprepared and not always comfortable teaching math. Professional development (PD) in early mathematics is widely considered a main way to increase teachers' skills and efficacy (e.g., Guskey, 2000; Hyson & Woods, 2014; Munby, Russell, & Martin, 2001; Piasta, Logan, Pelatti, Capps, & Petrill, 2015; Richardson & Placier, 2001; Sarama, Clements, Wolfe, & Spitler, 2016; Sarama & DiBiase, 2004; Zaslow, 2014). However, it has been documented that stand-alone PD is not as effective in changing practice (e.g., Biancarosa & Bryk, 2011; Garet et al., 2008; Guskey, 2000; Hyson & Woods, 2014; Institute of Medicine and National Research Council, 2015; Joyce & Showers, 2002; Zaslow, 2014). Site-embedded ongoing support in the form of coaching or mentoring has been shown to be critical for successful implementation (Neuman & Cunningham, 2009; Powell, Diamond, Burchinal, & Koehler, 2010). In this chapter, we describe coaching models and abstract characteristics of effective coaching from the research. With this background, we provide an in-depth view of the coaching aspect of two large empirical studies in early mathematics. We introduce the theoretical framework from which the coaching models for these projects were developed and describe the research on which they were based. We then summarize how the planned models were instantiated and challenges to their implementation within each project. In the final section, we summarize what we have learned and described implications and challenges for the field. © 2017 Elsevier Inc. All rights reserved.

  14. Early Treatment in Shock

    Science.gov (United States)

    2011-06-01

    Figure 1). We conclude the inclusion of L-2 arginine in the resuscitation fluid has a statistically significant early beneficial and pro-3 tective...contribution of the intervention on survival. Statistical Analysis Sample size for rats used in both the acute and chronic experiments was calculated...prolongs survival in a rat model of lethal hypoxemia . Crit Care Med. 2000;28:1968-1972. 6. Giassi LJ, Gilchrist MJ, Graham BA, Gainer JL. Trans-sodium

  15. Hands of early primates.

    Science.gov (United States)

    Boyer, Doug M; Yapuncich, Gabriel S; Chester, Stephen G B; Bloch, Jonathan I; Godinot, Marc

    2013-12-01

    Questions surrounding the origin and early evolution of primates continue to be the subject of debate. Though anatomy of the skull and inferred dietary shifts are often the focus, detailed studies of postcrania and inferred locomotor capabilities can also provide crucial data that advance understanding of transitions in early primate evolution. In particular, the hand skeleton includes characteristics thought to reflect foraging, locomotion, and posture. Here we review what is known about the early evolution of primate hands from a comparative perspective that incorporates data from the fossil record. Additionally, we provide new comparative data and documentation of skeletal morphology for Paleogene plesiadapiforms, notharctines, cercamoniines, adapines, and omomyiforms. Finally, we discuss implications of these data for understanding locomotor transitions during the origin and early evolutionary history of primates. Known plesiadapiform species cannot be differentiated from extant primates based on either intrinsic hand proportions or hand-to-body size proportions. Nonetheless, the presence of claws and a different metacarpophalangeal [corrected] joint form in plesiadapiforms indicate different grasping mechanics. Notharctines and cercamoniines have intrinsic hand proportions with extremely elongated proximal phalanges and digit rays relative to metacarpals, resembling tarsiers and galagos. But their hand-to-body size proportions are typical of many extant primates (unlike those of tarsiers, and possibly Teilhardina, which have extremely large hands). Non-adapine adapiforms and omomyids exhibit additional carpal features suggesting more limited dorsiflexion, greater ulnar deviation, and a more habitually divergent pollex than observed plesiadapiforms. Together, features differentiating adapiforms and omomyiforms from plesiadapiforms indicate increased reliance on vertical prehensile-clinging and grasp-leaping, possibly in combination with predatory behaviors in

  16. Early Archaean hydrothermal systems

    Science.gov (United States)

    de Vries, S. T.; Nijman, W.

    2003-04-01

    Although many people have written about hydrothermal systems in the early Earth, little real evidence is available. New data from the Barberton greenstone belt (South Africa) and greenstone belts of the East Pilbara (Western Australia), provide proof of the existence and nature of hydrothermal systems in the Early Archaean (around 3.4 Ga). Detailed field relationships between vein systems, host rock and overlying sediments are combined with data from fluid inclusions studies on quartz fills in the sediments. An intimate relationship between chert veins and the overlying sediments has been established (the veins are syn-sedimentary). The salinity and temperature of the fluids in the inclusions shows that these are of hydrothermal origin. Similar types of hydrothermal systems, of approximately the same age, have been found at different locations; in the Barberton greenstone belt and at various locations in the East Pilbara. The setting of these hydrothermal systems is not always identical however. Although a felsic substratum is more common, in the North Pole area (Pilbara) the hydrothermal systems rise from a basaltic substratum. In the Barberton greenstone belt, the systems are closely related to shallow intrusive (felsic) bodies. The study of these ancient hydrothermal systems forms an important framework for studies of early life on Earth. This study forms part of an international project on Earth's Earliest Sedimentary Basins, supported by the Foundation Dr. Schürmannfonds.

  17. [Early stimulation > programs evaluation].

    Science.gov (United States)

    Bonnier, C

    2007-09-01

    Early intervention include educational and neuroprotection strategies. Early educational strategies are based on the cerebral plasticity concept. Neuroprotection, initially reserved for molecules preventing cell death phenomena, can be extended now to all actions promoting harmonious development and preventing handicaps, and include organisational, therapeutic and environmental aspects. Early stimulation programs have been first devised in United States for vulnerable children who belong to an unfavorable socio-economic category ; positive effects were recorded in school failure rates and social problems ; programs have also been launched in several countries for premature infants and infants with a low birth weight, population exposed to a high risk of deficiencies. The programs are targetted either to the child, or to the parents, or combined to provide assistance for both the child and the parents. The programs given the best evaluation are NIDCAP Program in Sweden (Newborn Individualized Developmental Care and Assessment Program), intended for babies neonatal intensive care units, then a longitudinal, multisite program, known as IHDP (Infant Health and Development Program). It was launched in United States for infants stimulation is maintained and when mothers have a low level of education.

  18. 19 January 2011 - British University of Manchester, Vice-President and Dean for the Faculty of Engineering and Physical Sciences Professor of Structural Engineering School of Mechanical, Aerospace and Civil Engineering C. Bailey in CERN Control Centre with Department Head P. Collier; at LHCb with R. Lindner and ATLAS underground experimental area with Deputy Spokesperson D. Charlton, througout accompanied by . Collier with R. Appleby and F. Loebinger

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    19 January 2011 - British University of Manchester, Vice-President and Dean for the Faculty of Engineering and Physical Sciences Professor of Structural Engineering School of Mechanical, Aerospace and Civil Engineering C. Bailey in CERN Control Centre with Department Head P. Collier; at LHCb with R. Lindner and ATLAS underground experimental area with Deputy Spokesperson D. Charlton, througout accompanied by . Collier with R. Appleby and F. Loebinger

  19. Developmental Milestones of Early Literacy

    Science.gov (United States)

    ... Size Email Print Share Developmental Milestones of Early Literacy Page Content ​In the spirit of making both ... at the well-defined developmental milestones of early literacy. Younger Than 6 Months: Never Too Young Unlike ...

  20. Early Mobilization: Changing the Mindset

    National Research Council Canada - National Science Library

    Castro, Emily; Turcinovic, Michael; Platz, John; Law, Isabel

    2015-01-01

    .... To assess and improve the mindset of SICU staff toward early mobilization of patients receiving mechanical ventilation before, 6 months after, and 1 year after implementation of early mobilization...

  1. Early Life Exposures and Cancer

    Science.gov (United States)

    Early-life events and exposures have important consequences for cancer development later in life, however, epidemiological studies of early-life factors and cancer development later in life have had significant methodological challenges.

  2. Early prevention of obesity

    Directory of Open Access Journals (Sweden)

    Claudio Maffeis

    2014-06-01

    Full Text Available Childhood obesity is the metabolic disorder with the highest prevalence in both children and adults. Urgency to treat and prevent childhood obesity is based on the clear evidence that obesity tends to track from childhood to adulthood, is associated to morbidity also in childhood and to long-term mortality. Early life, i.e., intrauterine life and the first two years, is a sensitive window for prevention. Anatomical and functional maturation of the hypothalamic structures devoted to regulating energy intake and expenditure and body size mainly occurs in the first 1,000 days of life. Therefore, factors affecting the foetal exposition to maternal metabolic environment and early postnatal nutrition are crucial in modulating the definition of the metabolic programming processes in the brain. Maternal diseases, mainly malnutrition for defect or excess, obesity and diabetes, placental disorders and dysfunctions, maternal use of alcohol and drugs, smoking, affect long term metabolic programming of the foetus with lifelong consequences. Similarly, early nutrition contributes to complete the long-term metabolic regulating framework initiated in the uterus. Breastfeeding, adequate weaning, attention to portion size and diet composition are potential tools for reducing the obesity risk later in childhood. Longitudinal randomized controlled studies are needed for exploring the efficacy of obesity prevention strategies initiated after conception.Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiou

  3. Early Onset Werner Syndrome

    Directory of Open Access Journals (Sweden)

    Berna İmge Aydoğan

    2015-09-01

    Full Text Available Werner syndrome (WS is a rare autosomal recessive adult-onset progeroid disorder characterized by the early onset of aged-appearance and age-related metabolic disorders. Symptoms of premature aging usually first develop in the second-third decades of life. We report a 27-year-old female who was admitted to our clinic at the age of eighteen with hyperglycemia. She was diagnosed with diabetes and type 4 dyslipidemia at the age of seven. In her family history, her parents were first cousins and she had three healthy brothers. On her first physical examination; she had bird-like face appearance, global hair loss, beaked nose, short stature and she was overweight. She had global hair loss with gray and thin hair. Hoarseness of voice and hyperkeratosis of skin were observed. She had bilateral cataracts and moderate sensorineural hearing loss. On psychiatric examination, borderline mental retardation was detected. She had severe insulin resistance and hypertriglyceridemia despite levothyroxine, gemfibrozil, omega-3 and intensive insulin treatment. Routine lipid apheresis was performed to lower the triglyceride levels reaching 5256 mg/dL. She also had focal segmental glomerulosclerosis, hepatosteatosis, osteoporosis and epilepsy. Disease was accompanied by several congenital deformities, such as Rathke’s cleft cyst, angiomyolipoma and femoral neck hypoplasia. WS is a rare genetic disorder characterized by multiple endocrine manifestations as well as soft tissue changes. We present a case of early disturbances that were diagnosed before typical clinical signs and symptoms. We propose that WS should be kept in mind when type 2 diabetes and hyperlipidemia are diagnosed early in childhood. Turk Jem 2015; 19: 99-104

  4. Value-Added Early Learning

    Science.gov (United States)

    Dichter, Harriet

    2011-01-01

    Elected state leaders often prioritize economic prosperity and competitiveness, which provides an important opportunity too rarely taken for investing in early education. In 2003, Pennsylvania recognized the connection between early education and the economy, and smartly embraced early learning as part of its economic prosperity and…

  5. Early Attrition among Suicidal Clients

    Science.gov (United States)

    Surgenor, P. W. G.; Meehan, V.; Moore, A.

    2016-01-01

    The study aimed to identify the level of suicidal ideation in early attrition clients and their reasons for the early termination of their therapy. The cross-sectional design involved early attrition clients (C[subscript A]) who withdrew from therapy before their second session (n = 61), and continuing clients who (C[subscript C]) progressed…

  6. [Early gastric cancer. Clinical contribution].

    Science.gov (United States)

    Pillitu, A; Carletti, N; Durzi, S; Terzi, G; Menghini, L; Degli Albizi, S

    1992-01-01

    The authors report their experience on 37 cases of Early Gastric Cancer on 1978-1990 period. They underline the excellent results obtained with subtotal gastrectomy and lynphectomy without deaths neither returns. They stress the diagnostic precision of endoscopic exam now of first choice in the early diagnosis of Early Gastric Cancer.

  7. Sonority and early words

    DEFF Research Database (Denmark)

    Kjærbæk, Laila; Boeg Thomsen, Ditte; Lambertsen, Claus

    2015-01-01

    Syllables play an important role in children’s early language acquisition, and children appear to rely on clear syllabic structures as a key to word acquisition (Vihman 1996; Oller 2000). However, not all languages present children with equally clear cues to syllabic structure, and since...... acquisition therefore presents us with the opportunity to examine how children respond to the task of word learning when the input language offers less clear cues to syllabic structure than usually seen. To investigate the sound structure in Danish children’s lexical development, we need a model of syllable...

  8. Crowdsourced earthquake early warning

    Science.gov (United States)

    Minson, Sarah E.; Brooks, Benjamin A.; Glennie, Craig L.; Murray, Jessica R.; Langbein, John O.; Owen, Susan E.; Heaton, Thomas H.; Iannucci, Robert A.; Hauser, Darren L.

    2015-01-01

    Earthquake early warning (EEW) can reduce harm to people and infrastructure from earthquakes and tsunamis, but it has not been implemented in most high earthquake-risk regions because of prohibitive cost. Common consumer devices such as smartphones contain low-cost versions of the sensors used in EEW. Although less accurate than scientific-grade instruments, these sensors are globally ubiquitous. Through controlled tests of consumer devices, simulation of an Mw (moment magnitude) 7 earthquake on California’s Hayward fault, and real data from the Mw 9 Tohoku-oki earthquake, we demonstrate that EEW could be achieved via crowdsourcing.

  9. Early solar physics

    CERN Document Server

    Meadows, A J

    1970-01-01

    Early Solar Physics reviews developments in solar physics, particularly the advent of solar spectroscopy and the discovery of relationships between the various layers of the solar atmosphere and between the different forms of solar activity. Topics covered include solar observations during 1843; chemical analysis of the solar atmosphere; the spectrum of a solar prominence; and the solar eclipse of December 12, 1871. Spectroscopic observations of the sun are also presented. This book is comprised of 30 chapters and begins with an overview of ideas about the sun in the mid-nineteenth century, fo

  10. Early Identification of Reading Difficulties

    DEFF Research Database (Denmark)

    Poulsen, Mads; Nielsen, Anne-Mette Veber; Juul, Holger

    2017-01-01

    Early screening for reading difficulties before the onset of instruction is desirable because it allows intervention that is targeted at prevention rather than remediation of reading difficulties. However, early screening may be too inaccurate to effectively allocate resources to those who need...... as much information as the early measures combined. In the light of these results and a less than perfect early screening accuracy, a new strategy for screening is introduced and discussed. The strategy proposes multi-point screening with gradually increasing sensitivity to strike a balance between...... manageable screening procedures and outcomes and early identification of students who are most likely in need of extra resources....

  11. [In-patient (early) rehabilitation].

    Science.gov (United States)

    Wallesch, Claus-W; Lautenschläger, Sindy

    2017-04-01

    It is difficult to develop the financing and hospital provision of interventions for early rehabilitation within the diagnosis-related group (DRG) system. In addition to a range of partially rehabilitative complex interventions, the system recognizes three main forms of early rehabilitative interventions: geriatric, neurological/neurosurgical, and interdisciplinary and others. In this article, the appropriate definitions and cost-effectiveness of these procedures are analyzed and compared. The early rehabilitative interventions are characterized by constant cooperation in the therapeutic team, especially neurological early rehabilitation through the incorporation of nursing as a therapeutic profession. Whereas geriatric and neurological early rehabilitation are reflected in the DRG system, the former provided in many general hospitals and the latter mainly in specialized institutions, interdisciplinary early rehabilitation has only occasionally been represented in the DRG system so far. If all acute in-patients who require early rehabilitation should receive such an intervention, an additional fee must be implemented for this this interdisciplinary service.

  12. Intentional switches between bimanual coordination patterns are primarily effectuated by the nondominant hand

    NARCIS (Netherlands)

    de Poel, HJ; Peper, CE; Beek, PJ

    Based on indications that hand dominance is characterized by asymmetrical interlimb coupling strength (with the dominant hand exerting stronger influences on the nondominant hand than vice versa), intentional switches between rhythmic bimanual coordination patterns were predicted to be mediated

  13. The Relation Between Malnutrition and the Exocrine Pancreas: A Systematic Review

    NARCIS (Netherlands)

    Bartels, Rosalie H.; van den Brink, Deborah A.; Bandsma, Robert H.; Boele van Hensbroek, Michael; Tabbers, Merit M.; Voskuijl, Wieger P.

    2018-01-01

    The relation between malnutrition and exocrine pancreatic insufficiency (EPI) has been described previously, but it is unclear if malnutrition leads to EPI or vice versa. We systematically synthesized current evidence evaluating the association between malnutrition and EPI in children. Pubmed,

  14. The relationship between confidence in charitable organizations and volunteering revisited

    NARCIS (Netherlands)

    Bekkers, René H.F.P.; Bowman, Woods

    2009-01-01

    Confidence in charitable organizations (charitable confidence) would seem to be an important prerequisite for philanthropic behavior. Previous research relying on cross-sectional data has suggested that volunteering promotes charitable confidence and vice versa. This research note, using new

  15. GUIDELINE THE RECRUITMENT PROCESS THROUGH INTERCULTURALITY USING INFORMATION SYSTEMS

    National Research Council Canada - National Science Library

    Beniamin G. BOŞCAI; Doina DĂNĂIAŢĂ

    2014-01-01

    ... of employees with different cultural backgrounds in organizations. Relating to interculturality, information systems have a crucial role by establishing the link between the recruiter and candidate, and vice versa...

  16. Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?

    DEFF Research Database (Denmark)

    Bagger, Y Z; Rasmussen, Henrik Berg; Alexandersen, P

    2007-01-01

    Epidemiological observations suggest links between osteoporosis and risk of acute cardiovascular events and vice versa. Whether the two clinical conditions are linked by common pathogenic factors or atherosclerosis per se remains incompletely understood. We investigated whether serum lipids...

  17. Ekphrasis’ and Fanopeia’s Effects in the cinematic representation of The RighStuff

    National Research Council Canada - National Science Library

    Silvio Ricardo Demétrio; Gisele Krodel Rech

    2014-01-01

    .... Based on concepts from rhetoric and literary theory - read ekphrasis and fanopeia - which deal with literary representations of images and vice-versa, we intend to seek similarities and differences...

  18. The Co-evolution of Internationalization and Technological Knowledge

    DEFF Research Database (Denmark)

    Geisler Asmussen, Christian; Hashai, Niron; Delios, Andrew

    2011-01-01

    but diminishing effect of technological knowledge on internationalization and vice versa. This relationship leads to equilibrium in the technological knowledge-internationalization space that dictates the patterns of technological and international evolution of MNEs. The model offers an integrative approach...

  19. Normal Child Behavior

    Science.gov (United States)

    ... age. Development can be uneven, too, with a child's social development lagging behind his intellectual growth, or vice versa. ... members, and others. They may interfere with the child's intellectual development. ... or social mores. They might include very aggressive or destructive ...

  20. 76 FR 17146 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; Endangered...

    Science.gov (United States)

    2011-03-28

    ... agencies are our primary conservation partners, and we routinely share data with them (and vice versa... burdensome for species that produce large numbers of young at a time (e.g., fish, amphibians, and butterflies...

  1. Getting closer: the effects of personalized and interactive online political communication

    NARCIS (Netherlands)

    Kruikemeier, S.; van Noort, G.; Vliegenthart, R.; de Vreese, C.H.

    2013-01-01

    Political parties and politicians increasingly use the possibilities of the Internet to communicate interactively with citizens and vice versa. The Internet also offers opportunities for individual politicians to profile themselves. These developments are often said to bring politics closer to

  2. Electoral participation and intergenerational transmission among Turkish migrants in Western Europe

    NARCIS (Netherlands)

    Spierings, N.

    2016-01-01

    This study investigates whether immigration affects the extent to which children of migrants are likelier to vote if their parents vote (and vice versa). It combines intergenerational transmission theories with migrant political participation theories. Existing studies of migration and

  3. CURRICULUM LEADERSIHP: STRATEGIES FOR LINKING THE WRITTEN AND DELIVERED CURRICULIM

    National Research Council Canada - National Science Library

    Lena Damovska

    2014-01-01

    ...) without neglecting the written curriculum(the theory), and vice versa, all the while analyzing strategies that will link both curricula and implement these conclusions in their further teaching...

  4. An overview on emerging bioelectrochemical systems (BESs): Technology for sustainable electricity, waste remediation, resource recovery, chemical production and beyond

    NARCIS (Netherlands)

    Bajracharya, S.; Sharma, M.; Mohanakrishna, Gunda; Benneton, Xochitl Dominguez; Strik, D.P.B.T.B.; Sarma, Priyangshu M.; Pant, Deepak

    2016-01-01

    Bioelectrochemical systems (BESs) are unique systems capable of converting chemical energy into electrical energy (and vice-versa) while employing microbes as catalysts. Such organic wastes including low-strength wastewaters and lignocellulosic biomass were converted into electricity with microbial

  5. Delayed disengagement of attention from snakes in children with autism

    National Research Council Canada - National Science Library

    Isomura, Tomoko; Ogawa, Shino; Shibasaki, Masahiro; Masataka, Nobuo

    2015-01-01

    ... image as the target among flower images is easier than vice versa. In this study, the degree of such search asymmetry was compared between 18 children with autism and 14 typically developing (TD) children...

  6. Cervical spine signs and symptoms: perpetuating rather than predisposing factors for temporomandibular disorders in women

    National Research Council Canada - National Science Library

    Bevilaqua-Grossi, Débora; Chaves, Thaís Cristina; de Oliveira, Anamaria Siriani

    2007-01-01

    ... and the severity of temporomandibular disorders (TMD) and vice-versa. One hundred women (aged 18-26 years) clinically diagnosed with TMD signs and symptoms and cervical spine disorders were randomly selected from a sample of college students...

  7. Resonant Electromagnetic Shunt Damping of Flexible Structures

    DEFF Research Database (Denmark)

    Høgsberg, Jan Becker

    2016-01-01

    Electromagnetic transducers convert mechanical energy to electrical energy and vice versa. Effective passive vibration damping of flexible structures can therefore be introduced by shunting with an accurately calibrated resonant electrical network thatcontains a capacitor to create the desired...

  8. Early-Onset Dementia

    DEFF Research Database (Denmark)

    Konijnenberg, Elles; Fereshtehnejad, Seyed-Mohammad; Kate, Mara Ten

    2017-01-01

    of this study was to investigate quality-of-care indicators in subjects with EOD from 3 tertiary memory clinics in 3 European countries. METHODS: We included 1325 newly diagnosed EOD patients, ages 65 years or younger, between January 1, 2007 and December 31, 2013, from the Danish Dementia Registry......BACKGROUND: Early-onset dementia (EOD) is a rare condition, with an often atypical clinical presentation, and it may therefore be challenging to diagnose. Specialized memory clinics vary in the type of patients seen, diagnostic procedures applied, and the pharmacological treatment given. The aim...... (Rigshospitalet, Copenhagen), the Swedish Dementia Registry ("SveDem", Karolinska University Hospital, Stockholm), and the Amsterdam Dementia Cohort (VU University Medical Center). RESULTS: The frequency of EOD among all dementia patients was significantly lower in Copenhagen (410, 20%) and Stockholm (284, 21...

  9. [Early cardiotoxicity of Hydroxychloroquine].

    Science.gov (United States)

    Zerbib, Y; Guillaumont, M P; Touati, G; Duhaut, P; Schmidt, J

    2016-03-01

    Hydroxychloroquine (HCQ) is most frequently used in the treatment of systemic inflammatory diseases. Cardiac complications of anti-malarial drugs are uncommon, and most of the time are the result of a long-term exposition. In this case, cardiotoxicity is the consequence of the lysosomal dysfunction and the result of intracytoplasmic granular material inclusions. We report a 77-year-old woman who presented a very early and reversible cardiotoxicity, probably related to the quinidine like effect of the HCQ, 10 days after initiation of therapy for Whipple endocarditis. We discuss the different mechanisms of cardiotoxicity of anti-malarial drugs and their clinical manifestations. Copyright © 2015 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  10. FLITECAM: early commissioning results

    Science.gov (United States)

    Logsdon, Sarah E.; McLean, Ian S.; Becklin, Eric E.; Dunham, Edward W.; Hamilton, Ryan T.; Johnson, Christopher; Milburn, Jennifer W.; Savage, Maureen L.; Shenoy, Sachindev S.; Smith, Erin C.; Vacca, William D.

    2014-07-01

    We present a status report and early commissioning results for FLITECAM, the 1-5 micron imager and spectrometer for SOFIA (the Stratospheric Observatory for Infrared Astronomy). In February 2014 we completed six flights with FLITECAM mounted in the FLIPO configuration, a co-mounting of FLITECAM and HIPO (High-speed Imaging Photometer for Occultations; PI Edward W. Dunham, Lowell Observatory). During these flights, the FLITECAM modes from ~1-4 μm were characterized. Since observatory verification flights in 2011, several improvements have been made to the FLITECAM system, including the elimination of a light leak in the FLITECAM filter wheel enclosure, and updates to the observing software. We discuss both the improvements to the FLITECAM system and the results from the commissioning flights, including updated sensitivity measurements. Finally, we discuss the utility of FLITECAM in the FLIPO configuration for targeting exoplanet transits.

  11. A short introduction to frames, Gabor systems, and wavelet systems

    DEFF Research Database (Denmark)

    Christensen, Ole

    2014-01-01

    In this article we present a short survey of frame theory in Hilbert spaces. We discuss Gabor frames and wavelet frames, and a recent transform that allows to move results from one setting into the other and vice versa.......In this article we present a short survey of frame theory in Hilbert spaces. We discuss Gabor frames and wavelet frames, and a recent transform that allows to move results from one setting into the other and vice versa....

  12. Methods and Systems for Measurement and Estimation of Normalized Contrast in Infrared Thermography

    Science.gov (United States)

    Koshti, Ajay M. (Inventor)

    2015-01-01

    Methods and systems for converting an image contrast evolution of an object to a temperature contrast evolution and vice versa are disclosed, including methods for assessing an emissivity of the object; calculating an afterglow heat flux evolution; calculating a measurement region of interest temperature change; calculating a reference region of interest temperature change; calculating a reflection temperature change; calculating the image contrast evolution or the temperature contrast evolution; and converting the image contrast evolution to the temperature contrast evolution or vice versa, respectively.

  13. A Computational Analysis of Mental Image Generation: Evidence from Functional Dissociations in Split-Brain Patients.

    Science.gov (United States)

    1984-08-20

    Approximately I sec after the cue was given verbally , a word was briefly presented to one visual field or the other. The subject had to pick out the...neuropsychological data on the apraxias and the visual agnosias imply that motor and visual memories can be separately spared or destroyed after brain...agraphia Imagery dissociations 53 and (vice versa), and visual object agnosia without apraxia (and vice versa). We next asked him to *draw the letters in

  14. Methods and Systems for Measurement and Estimation of Normalized Contrast in Infrared Thermography

    Science.gov (United States)

    Koshti, Ajay M. (Inventor)

    2017-01-01

    Methods and systems for converting an image contrast evolution of an object to a temperature contrast evolution and vice versa are disclosed, including methods for assessing an emissivity of the object; calculating an afterglow heat flux evolution; calculating a measurement region of interest temperature change; calculating a reference region of interest temperature change; calculating a reflection temperature change; calculating the image contrast evolution or the temperature contrast evolution; and converting the image contrast evolution to the temperature contrast evolution or vice versa, respectively.

  15. Peer Bullying During Early Childhood

    OpenAIRE

    Hatice UYSAL; Çağlayan DİNÇER

    2012-01-01

    Peer bullying during early childhood is discussed along with the literature reviewed in this article with the purpose of drawing attention to peer bullying during early childhood and its significance, and contributing to studies which are few in number in Turkey. Peer bullying during early childhood was considered with its definition and types, people who play key roles in peer bullying, factors (gender, age, parents, and friendship) that relate to peer bullying, and what should be done befor...

  16. [The early diagnosis of spondyloarthritis].

    Science.gov (United States)

    Novak, Srdan

    2011-01-01

    The most frequent early symptoms of spondyloarthritides are inflammatory back pain and asymetric peripheral arthritis. Currently the mean delay between the onset of first symptoms and diagnosing ankylosing spondylitis which is the frequent type of spondyloarthritis is over 5 years. The availability of effective therapies makes an early diagnosis mandatory. The clinical symptoms of inflammatory back pain, active inflamation on MR, and positivity for HLA-B27 are the most important parameters for an early diagnosis of spondyloarthritis, especially in combination. Moreover, the combination of clinical and laboratory parameters is necessary for the early diagnosis.

  17. Early onset dementia.

    Science.gov (United States)

    Fadil, Halim; Borazanci, Aimee; Ait Ben Haddou, Elhachmia; Yahyaoui, Mohamed; Korniychuk, Elena; Jaffe, Stephen L; Minagar, Alireza

    2009-01-01

    Dementia is characterized by a decline in cognitive faculties and occurrence of behavioral abnormalities which interfere with an individual's activities of daily living. Dementing disorders usually affect elderly individuals but may occur in individuals younger than 65 years (early-onset dementia or EOD). EOD is often misdiagnosed or its diagnosis is delayed due to the fact that it has a more varied differential diagnosis than late-onset dementia. EOD affects individuals at the height of their career and productivity and produces devastating consequences and financial loss for the patient's family as well as society. EOD is not uncommon and is diagnosed in up to a third of patients presenting with dementia. Most importantly, some of the causes of EOD are curable which makes the need for a specific and timely diagnosis crucial. The present chapter presents a systematic approach to the differential diagnosis of EOD and provides readers with the clinical and neuroimaging features of these disorders as well as important considerations for their diagnostic evaluation. Specifically, the nuances of assessing the history and examination are discussed with careful attention to the various methods of cognitive and behavioral evaluation. A step-wise approach to diagnostic testing is followed by a discussion of anatomical localization, which often aids in identifying specific etiologies. Finally, in order to organize the subject for the reader, the various etiologies are grouped under the general categories of vascular, infectious, toxic-metabolic, immune-mediated, neoplastic/metastatic, and neurodegenerative.

  18. Early diagnosis of leptospirosis

    Directory of Open Access Journals (Sweden)

    Andrea Babic-Erceg

    2014-06-01

    Full Text Available A 25-years old man from Zagreb, Croatia, was admitted to the University Hospital for Infectious Diseases four days after the onset of symptoms such as fever, intense pain in the calves and anuria. The patient owned a rabbit and, before the onset of the disease, repaired some rubber pipes damaged by rodents. At admission, he had a severe clinical picture with fever, hypotension, jaundice, immobility, and pain in leg muscles. Treatment with ceftriaxone was initiated in combination with volume restitution. Renal failure soon ensued. Consequently continuous venovenous hemodiaphiltration therapy was performed. Due to acute respiratory distress syndrome, the patient was mechanically ventilated. The patient’s condition gradually improved and he recovered fully from multi-organ failure. Diagnosis was confirmed by a microscopic agglutination test (MAT covering 15 leptospira serovars and real-time polymerase-chain reaction (PCR. The first serum sample taken on day 6 tested negative for leptospira, while PCR showed positive results for leptospiral DNA. The second serum sample taken on day 13 tested positive for serovar Canicola serogroup Canicola, serovar Patoc, serovar Grippotyphosa serogroup Grippotyphosa and serovar Tarassovi serogroup Tarassovi (titre 4000, 4000, 1000 and 2000, respectively, while PCR was negative. This report highlights the benefits of combining MAT and PCR methods in early diagnosis of leptospirosis.

  19. EARLY ENTRANCE COPRODUCTION PLANT

    Energy Technology Data Exchange (ETDEWEB)

    Mushtaq Ahmed; John H. Anderson; Charles Benham; Earl R. Berry; Fred Brent; Ming He; Troy Raybold; Lalit S. Shah; Kenneth A. Yackly

    2003-09-09

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produces at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objectives of Phase I were to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan for implementation in Phase II; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The project will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation.

  20. Early Repolarization Syndrome

    Directory of Open Access Journals (Sweden)

    Frederic Sacher

    2015-04-01

    Full Text Available The electrocardiographic pattern of early repolarization (ER is common, with a particularly high prevalence reported amongst athletes and adolescents. It has long been associated with benign outcome [1-3]. Recently, an association between inferolateral ER pattern and sudden cardiac death (SCD has been established by different groups [4-7]. Population-based studies have also reported an increased mortality rate among patients with inferolateral ER pattern compared to controls [7-9]. To bring back together these differences, it is important to focus on the definition of ER pattern used in these different studies as well as the population included. The definition of ER pattern associated with sudden cardiac death was the presence of J point elevation more than or equal to 0.1mV in at least 2 contiguous inferior and/or lateral leads of a standard 12-lead ECG and not ST elevation as it was often the case in the studies with benign outcome. Any study dealing with ER should clearly indicate the definition used. Otherwise it cannot be interpreted. Talking about definition, ER syndrome is an ER pattern (as defined above associated with symptoms (syncope or aborted SCD and/or familial history of SCD as mentioned in the last HRS/EHRA/APHRS Expert Consensus Statement on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes [10]. It is important to recognise that having only an ER pattern is not a disease.

  1. Vice-Chancellors Influence on Academic Staff Intentions to Use ...

    African Journals Online (AJOL)

    kmacharia

    adoption and diffusion of Learning Management System (LMS) by academic staff for teaching and learning ... response to the web-based Learning Management System (LMS) for instructional and course delivery in ..... environment, where the VC is the project champion with a clear vision and offers project leadership.

  2. Former health care vice minister sentenced / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2010-01-01

    Leedu endise tervishoiu aseministri Arturas Skikase kohtuotsusest seoses altkäemaksu võtmisega. Arturas Skikas tunnistas üles, et soovis saada verekeskuse direktori käest 5800 eurot. Tervishoiuminister Algis Caplikas jääb ametisse

  3. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    BB

    Purpose: Attend the World Strategic Forum. Date(s):. 2017-04-18 to 2017-04-20. Destination(s):. Miami, USA. Airfare: $399.92. Other. Transportation: $101.41. Accommodation: $0.00. Meals and. Incidentals: $466.55. Other: $0.00. Total: $967.88. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette ...

  4. 2017-2018 Travel Expense Reports for Chandra Madramootoo, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    07-11. Destination(s):. Kenya, Uganda and Tanzania. Airfare: $4,788.97. Other. Transportation: $147.43. Accommodation: $2,058.50. Meals and. Incidentals: $701.92. Other: $399.15. Total: $8,095.97. Comments: From residence in Montreal, ...

  5. 2017-2018 Travel Expense Reports for Sylvain Dufour, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    09-30 to 2017-10-06. Destination(s):. Orlando, FL (USA). Airfare: $751.97. Other. Transportation: $228.39. Accommodation: $1,102.96. Meals and. Incidentals: $1,342.07. Other: $7.51. Total: $3,432.90. Comments: 2017-2018 Travel Expense ...

  6. Vice-Chancellors Influence on Academic Staff Intentions to Use ...

    African Journals Online (AJOL)

    Universities world over are increasingly deploying learning management systems to enhance the quality of teaching and learning as well as to increase access to higher education. However, since technology rejection is common, the future of universities depends on their instructor's capacity to adopt and diffuse such ...

  7. FOOD AND VICES IN SOUTH-EASTERN NIGERIA: IMPLICATIONS ...

    African Journals Online (AJOL)

    procrastination and laziness on the part of individuals; fatalism (the belief that fate determines the status of every human being); poor implementation of government's policies on rural development, lack of assistance to willing Small and Medium Scale Entrepreneurs and farmers; high cost of goods and services in the market ...

  8. Vice-Principal Research: A Window on the Building.

    Science.gov (United States)

    Iannaccone, Laurence

    1985-01-01

    Proposes that the role of the secondary school assistant principal should be studied in terms of the dynamics of basic political conflicts in schools. When seen as a polity, the school site is full of disturbances that can potentially expand into conflicts; the assistant principals' typical function is to respond to these disturbances. (KH)

  9. Leadership and Management: Command Philosophy Vice Executive Philosophy

    Science.gov (United States)

    1989-03-15

    source of low cost lendable funds. They may be artistic, such as a new form of musical reproduction like multiplex stereo. They may be intangible and...IwmAWOrgmsid% 12)45 kAdaissitmtis skills 12345 COMMuictio; skills 12345 ftoblm MIT*rIdecision at" lam 12345 In ddition to the ibo Mnntm#Msklls 12)45

  10. President Ilves and Vice-President Cheney meet

    Index Scriptorium Estoniae

    2008-01-01

    President Toomas Hendrik Ilvese kohtumisel Ameerika Ühendriikide asepresidendi Richard B. Cheney'ga olid peamiste teemadena arutlusel energiajulgeolek ning arengud Gruusias, samuti käsitleti arenguid Afganistani ja Iraagi missioonidel. Vabariigi President töövisiidil Ameerika Ühendriikides 17.-23.04.2008

  11. Vice-Chancellors Influence on Academic Staff Intentions to Use ...

    African Journals Online (AJOL)

    kmacharia

    Wannemacher, 2006). Consequently, universities must face the challenge in having to get academic staff to adopt and make effective use of them in teaching and learning since technology rejection is common. (Davis F. D., 1989; Davis, Bagozzi, ...

  12. Executive Assistant - Vice-President, Programs and Partnerships ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In collaboration with the Senior Programs Advisor , tracks Branch operational expenditures, reviews accounting reports, determines spending patterns, and plans for upcoming expenses. Coordinates the Branch annual intake of summer students, from calculating how many can be hired according to budget and office space ...

  13. Early tetrapod relationships revisited.

    Science.gov (United States)

    Ruta, Marcello; Coates, Michael I; Quicke, Donald L J

    2003-05-01

    In an attempt to investigate differences between the most widely discussed hypotheses of early tetrapod relationships, we assembled a new data matrix including 90 taxa coded for 319 cranial and postcranial characters. We have incorporated, where possible, original observations of numerous taxa spread throughout the major tetrapod clades. A stem-based (total-group) definition of Tetrapoda is preferred over apomorphy- and node-based (crown-group) definitions. This definition is operational, since it is based on a formal character analysis. A PAUP* search using a recently implemented version of the parsimony ratchet method yields 64 shortest trees. Differences between these trees concern: (1) the internal relationships of aïstopods, the three selected species of which form a trichotomy; (2) the internal relationships of embolomeres, with Archeria crassidisca and Pholiderpeton scut collapsed in a trichotomy with a clade formed by Anthracosaurus russelli and Pholiderpeton attheyi; (3) the internal relationships of derived dissorophoids, with four amphibamid species forming an unresolved node with a clade consisting of micromelerpetontids and branchiosaurids and a clade consisting of albanerpetontids plus basal crown-group lissamphibians; (4) the position of albenerpetontids and Eocaecilia micropoda, which form an unresolved node with a trichotomy subtending Karaurus sharovi, Valdotriton gracilis and Triadobatrachus massinoti; (5) the branching pattern of derived diplocaulid nectrideans, with Batrachiderpeton reticulatum and Diceratosaurus brevirostris collapsed in a trichotomy with a clade formed by Diplocaulus magnicornis and Diploceraspis burkei. The results of the original parsimony run--as well as those retrieved from several other treatments of the data set (e.g. exclusion of postcranial and lower jaw data; character reweighting; reverse weighting)--indicate a deep split of early tetrapods between lissamphibian- and amniote-related taxa. Colosteids, Crassigyrinus

  14. Early onset sebaceous carcinoma

    Directory of Open Access Journals (Sweden)

    Kaltreider Sara A

    2011-09-01

    Full Text Available Abstract Background Ocular sebaceous carcinoma can masquerade as benign lesions resulting in delay of diagnosis. Early recognition is even more difficult in young patients where the disease rarely occurs. Here, we provide a clinicopathological correlation of ocular sebaceous carcinoma in a young individual lacking history of hereditary cancer or immunosuppression. Findings A detailed histopathological study including p53 DNA sequencing was performed on an aggressive sebaceous carcinoma presenting in a healthy 32 year-old Caucasian woman. She had no history of retinoblastoma, evidence for a hereditary cancer syndrome, or radiation therapy. However, she potentially was at risk for excessive UV light exposure. A detailed review of the literature is also provided. A moderately well differentiated sebaceous carcinoma was established histopathologically arising from the meibomian gland of the upper eyelid. In most areas, the cytoplasm contained small but distinct Oil-red-O positive vacuoles. Direct sequencing of p53 identified a G:C→A:T mutation at a dipyrimidine site. The mutation results in substitution of arginine for the highly conserved glycine at residue 199 located at the p53 dimer-dimer interface. Energy minimization structural modeling predicts that G199R will neutralize negative charges contributed by nearby inter- and intramonomeric glutamate residues. Discussion This study points to the importance of recognizing that sebaceous carcinoma can occur in young patients with no evidence for hereditary cancer risk or radiation therapy. The G199R substitution is anticipated to alter the stability of the p53 tetrameric complex. The role of UV light in the etiology of sebaceous carcinoma deserves further study. Our findings, taken together with those of others, suggest that different environmental factors could lead to the development of sebaceous carcinoma in different patients.

  15. Early Entrance Coproduction Plant

    Energy Technology Data Exchange (ETDEWEB)

    Mushtaq Ahmed; John H. Anderson; Earl R. Berry; Troy Raybold; Lalit S. Shah; Kenneth A. Yackly

    2004-01-26

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objectives of Phase I were to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan for implementation in Phase II; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The work performed under Phase II will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation.

  16. EARLY ENTRANCE COPRODUCTION PLANT

    Energy Technology Data Exchange (ETDEWEB)

    Mushtaq Ahmed; John H. Anderson; Earl R. Berry; Troy Raybold; Lalit S. Shah; Kenneth A. Yackly

    2003-12-16

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or other carbonaceous feedstocks. The objectives of Phase I were to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan for implementation in Phase II; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology that produces high-value products, particularly those that are critical to our domestic fuel and power requirements. The work performed under Phase II will resolve critical knowledge and technology gaps on the integration of gasification and downstream processing to coproduce some combination of power, fuels, and chemicals from coal and/or other carbonaceous feedstocks. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation.

  17. Early identification of rheumatoid arthritis

    NARCIS (Netherlands)

    Nies, Jessica Annemarie Bernadette van

    2016-01-01

    The first part is focused on early recognition of Rheumatoid Arthritis (RA). Two large early arthritis recognition clinics were started in Leiden and Groningen. The results showed that this initiative reduces the GP-delay significantly. Secondly, it was investigated whether an association between

  18. Early Intervention in Bipolar Disorder.

    Science.gov (United States)

    Vieta, Eduard; Salagre, Estela; Grande, Iria; Carvalho, André F; Fernandes, Brisa S; Berk, Michael; Birmaher, Boris; Tohen, Mauricio; Suppes, Trisha

    2018-01-24

    Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is associated with high rates of morbidity and mortality, making bipolar disorder one of the main causes of disability among young and working-age people. The implementation of early intervention strategies may help to change the outcome of the illness and avert potentially irreversible harm to patients with bipolar disorder, as early phases may be more responsive to treatment and may need less aggressive therapies. Early intervention in bipolar disorder is gaining momentum. Current evidence emerging from longitudinal studies indicates that parental early-onset bipolar disorder is the most consistent risk factor for bipolar disorder. Longitudinal studies also indicate that a full-blown manic episode is often preceded by a variety of prodromal symptoms, particularly subsyndromal manic symptoms, therefore supporting the existence of an at-risk state in bipolar disorder that could be targeted through early intervention. There are also identifiable risk factors that influence the course of bipolar disorder, some of them potentially modifiable. Valid biomarkers or diagnosis tools to help clinicians identify individuals at high risk of conversion to bipolar disorder are still lacking, although there are some promising early results. Pending more solid evidence on the best treatment strategy in early phases of bipolar disorder, physicians should carefully weigh the risks and benefits of each intervention. Further studies will provide the evidence needed to finish shaping the concept of early intervention.

  19. Early determinants of mental health

    NARCIS (Netherlands)

    Räikkönen, Katri; Pesonen, Anu-Katriina; Roseboom, Tessa J.; Eriksson, Johan G.

    2012-01-01

    Environmental adversities in pre- and early postnatal life may have life-long consequences. Based upon a series of epidemiological and clinical studies and natural experiments, this review describes how the early life environment may affect psychological functions and mental disorders later in life.

  20. Early Childhood Inclusion in Spain

    Science.gov (United States)

    Giné, Climent; Balcells-Balcells, Anna; Cañadas, Margarita; Paniagua, Gema

    2016-01-01

    This article describes early childhood inclusion in educational settings in Spain. First, we address the legislative framework of preschool education in Spain and offer a brief analysis of some relevant issues, including the current situation of early childhood education and inclusion at this stage. Second, current policies and practices relating…

  1. Early Complications of Heart Transplantation

    OpenAIRE

    Schnee, Mark

    1987-01-01

    In cyclosporine-treated cardiac allograft recipients, rejection and infection are two principal early complications. The following report describes our approach to the diagnosis and management of rejection. Infectious complications are discussed elsewhere in this journal. Lymphoproliferative disorders have not been reported in our series of transplant recipients. Other early complications particularly related to cyclosporine immuno-suppressive therapy include systemic hypertension, renal insu...

  2. Early experience and brain development.

    Science.gov (United States)

    Bick, Johanna; Nelson, Charles A

    2017-01-01

    Healthy brain development takes place within the context of individual experience. Here, we describe how certain early experiences are necessary for typical brain development. We present evidence from multiple studies showing that severe early life neglect leads to alterations in brain development, which compromises emotional, behavioral, and cognitive functioning. We also show how early intervention can reverse some of the deleterious effects of neglect on brain development. We conclude by emphasizing that early interventions that start at the earliest possible point in human development are most likely to support maximal recovery from early adverse experiences. WIREs Cogn Sci 2017, 8:e1387. doi: 10.1002/wcs.1387 For further resources related to this article, please visit the WIREs website. © 2016 Wiley Periodicals, Inc.

  3. Early diagnosis and early intervention in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Mijna eHadders-Algra

    2014-09-01

    Full Text Available This paper reviews the opportunities and challenges for early diagnosis and early intervention in cerebral palsy (CP. CP describes a group of disorders of the development of movement and posture, causing activity limitation, that are attributed to disturbances that occurred in the fetal or infant brain. Therefore the paper starts with a summary of relevant information from developmental neuroscience. Most lesions underlying CP occur in the second half of gestation, when developmental activity in the brain reaches its summit. Variations in timing of the damage not only result in different lesions, but also in different neuroplastic reactions and different associated neuropathologies. This turns CP into a heterogeneous entity. This may mean that the best early diagnostics and the best intervention methods may differ for various subgroups of children with CP. Next, the paper addresses possibilities for early diagnosis. It discusses the predictive value of neuromotor and neurological exams, neuro-imaging techniques and neurophysiological assessments. Prediction is best when complementary techniques are used in longitudinal series. Possibilities for early prediction of CP differ for infants admitted to neonatal intensive care and other infants. In the former group best prediction is achieved with the combination of neuro-imaging and the assessment of general movements, in the latter group best prediction is based on carefully documented milestones and neurological assessment. The last part reviews early intervention in infants developing CP. Most knowledge on early intervention is based on studies in high risk infants without CP. In these infants early intervention programs promote cognitive development until preschool age; motor development profits less. The few studies on early intervention in infants developing CP suggest that programs that stimulate all aspects of infant development by means of family coaching are most promising. More research is

  4. EARLY ENTRANCE COPRODUCTION PLANT

    Energy Technology Data Exchange (ETDEWEB)

    David Storm; Govanon Nongbri; Steve Decanio; Ming He; Lalit Shah; Charles Schrader; Earl Berry; Peter Ricci; Belma Demirel; Charles Benham; Mark Bohn

    2004-01-12

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, Inc., GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. During Phase I, a design basis for the Fischer-Tropsch Synthesis section was developed based on limited experience with the specified feed gas and operating conditions. The objective of this Task in Phase II RD&T work was to confirm the performance of the F-T reactor at the set design conditions. Although much of the research, development, and testing work were done by TES outside of this project, several

  5. Early eruption of permanent canines

    Directory of Open Access Journals (Sweden)

    S Madhu

    2012-01-01

    Full Text Available Systemic and local factors can modify the eruption time of teeth. Generalized eruption time changes could be due to some systemic diseases like hyperthyroidism, hypophosphatasia, precocious puberty, Proteus syndrome, etc. Localized early eruption of permanent teeth could be due to early extraction of deciduous teeth. Presented here is an extremely rare case of early eruption of permanent canines in a 7-year old female child. Though the number of such cases is very limited, the clinician should poses adequate knowledge and keeps an open eye to identify such cases.

  6. Early vision and visual attention

    Directory of Open Access Journals (Sweden)

    Gvozdenović Vasilije P.

    2003-01-01

    Full Text Available The question whether visual perception is spontaneous, sudden or is running through several phases, mediated by higher cognitive processes, was raised ever since the early work of Gestalt psychologists. In the early 1980s, Treisman proposed the feature integration theory of attention (FIT, based on the findings of neuroscience. Soon after publishing her theory a new scientific approach appeared investigating several visual perception phenomena. The most widely researched were the key constructs of FIT, like types of visual search and the role of the attention. The following review describes the main studies of early vision and visual attention.

  7. EARLY ENTRANCE COPRODUCTION PLANT

    Energy Technology Data Exchange (ETDEWEB)

    John Anderson; Mark Anselmo; Earl Berry; Mark Bohn; Ming He; Charles H. Schrader; Lalit Shah; Donald Todd; Robert Schavey

    2004-01-12

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to its detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC (TES) (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR). The work was under cooperative agreements with the U.S. Department of Energy (DOE). TES is providing the gasification technology and the Fischer-Tropsch (F-T) technology developed by Rentech Inc., GE is providing the combustion turbine technology, Praxair is providing the air separation technology, and KBR is providing overall engineering. Each of the EECP's subsystems was assessed for technical risks and barriers in Phase I. A plan was identified to mitigate the identified risks (Phase II RD&T Plan, October 2000). The RD&T Plan identified catalyst/wax separation as a potential technical and economic risk. To mitigate risks to the proposed EECP concept, Phase II RD&T included

  8. EARLY ENTRANCE COPRODUCTION PLANT

    Energy Technology Data Exchange (ETDEWEB)

    Fred D. Brent; Lalit Shah; Earl Berry; Charles H. Schrader; John Anderson; Ming He; James F. Stevens; Centha A. Davis; Michael Henley; Jerome Mayer; Harry Tsang; Jimell Erwin; Jennifer Adams; Michael Tillman; Chris Taylor; Marjan J. Roos; Robert F. Earhart

    2004-01-27

    The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase II is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems was assessed for technical risks and barriers. A plan was developed to mitigate the identified risks (Phase II RD&T Plan, October 2000). The potential technical and economic risks to the EECP from Task 2.5 can be mitigated by demonstrating that the end-use products derived from the upgrading of the F-T synthesis total liquid product can meet or exceed current specifications for the

  9. The evolution of early Foraminifera.

    Science.gov (United States)

    Pawlowski, Jan; Holzmann, Maria; Berney, Cédric; Fahrni, José; Gooday, Andrew J; Cedhagen, Tomas; Habura, Andrea; Bowser, Samuel S

    2003-09-30

    Fossil Foraminifera appear in the Early Cambrian, at about the same time as the first skeletonized metazoans. However, due to the inadequate preservation of early unilocular (single-chambered) foraminiferal tests and difficulties in their identification, the evolution of early foraminifers is poorly understood. By using molecular data from a wide range of extant naked and testate unilocular species, we demonstrate that a large radiation of nonfossilized unilocular Foraminifera preceded the diversification of multilocular lineages during the Carboniferous. Within this radiation, similar test morphologies and wall types developed several times independently. Our findings indicate that the early Foraminifera were an important component of Neoproterozoic protistan community, whose ecological complexity was probably much higher than has been generally accepted.

  10. The early universe and cosmogenesis

    Science.gov (United States)

    Lukash, V. N.; Mikheeva, E. V.; Strokov, V. N.

    2013-05-01

    We extrapolate the Cosmological Standard Model to the past, determine initial geometrical conditions in the early universe, and consider a new cosmogenesis paradigm based on the concept of black-and-white holes with integrable singularities.

  11. Early rheumatoid arthritis: therapeutic strategies.

    Science.gov (United States)

    Emery, P

    1994-01-01

    The early stage of rheumatoid arthritis (RA) is a unique and critical phase of disease which is often characterized by profound inflammation, severe symptomatology and a high likelihood of radiological progression. Decisions on treatment strategies need to be taken before irreversible damage and functional deterioration occur. There is evidence that early intervention with disease-modifying drugs may reduce functional deterioration and improve long-term outcome. Stable genetic markers and rheumatoid factor are useful in predicting disease severity and thus in identifying those patients who require early aggressive therapy. The acute phase response (APR) is a valuable marker of disease activity and catabolism in RA, and suppression of the APR improves outcome. The use of early aggressive therapy to suppress disease efficiently in patients with a poor prognosis should improve the long-term morbidity and mortality associated with RA.

  12. Early onset type 2 diabetes

    DEFF Research Database (Denmark)

    Bo, A; Thomsen, R W; Nielsen, J S

    2017-01-01

    was more frequent and meeting physical activity recommendations less likely in persons with early-onset type 2 DM. CONCLUSIONS: We found a clear age-gradient, with increasing prevalence of clinical and behavioural risk factors the younger the onset age of type 2 DM. Younger persons with early-onset type 2......AIM: To examine the association between early onset of type 2 diabetes (DM) and clinical and behavioural risk factors for later diabetes complications. METHODS: We conducted a cross-sectional study of 5115 persons with incident type 2 DM enrolled during 2010-2015 in the Danish Centre for Strategic...... Research in Type 2 Diabetes-cohort. We compared risk factors at time of diagnosis among those diagnosed at ≤45 years (early-onset) with diagnosis age 46-55, 56-65 (average-onset = reference), 66-75, and >75 years (late-onset). Prevalence ratios (PRs) were computed using Poisson regression. RESULTS: Poor...

  13. [Early management of cerebrovascular accidents].

    Science.gov (United States)

    Libot, Jérômie; Guillon, Benoit

    2013-01-01

    A cerebrovascular accident requires urgent diagnosis and treatment.The management of a stroke must be early and adapted in order to improve the overall clinical outcome and lower the risk of mortality.

  14. The Diets of Early Hominins

    National Research Council Canada - National Science Library

    Peter S. Ungar; Matt Sponheimer

    2011-01-01

    Diet changes are considered key events in human evolution. Most studies of early hominin diets focused on tooth size, shape, and craniomandibular morphology, as well as stone tools and butchered animal bones...

  15. STARDUST NAVCAM EARLY CRUISE IMAGES

    Data.gov (United States)

    National Aeronautics and Space Administration — This volume contains the results of the early cruise images of the Stardust Navigation Camera. These images are of no clear scientific or engineering use. They were...

  16. Early Retiree Reinsurance Program Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Early Retiree Reinsurance Program (ERRP) was established by section 1102 of the Patient Protection and Affordable Care Act (the Affordable Care Act) enacted on...

  17. [Early diagnosis of skin cancer].

    Science.gov (United States)

    Kolm, Isabell; Hofbauer, Günther; Braun, Ralph P

    2010-09-01

    The skin is the most affected organ by cancer. The incidence rates of skin cancer are steadily increasing, both for melanoma and non-melanoma skin cancers (squamous cell carcinoma, basal cell carcinoma). Over 90 % of the death cases from skin cancers attribute to melanoma. Survival from melanoma is strongly related to tumour thickness. Therefore early detection is the most important step to improve prognosis. In the last years a number of new non invasive techniques for the early diagnosis of melanoma have been developed which are superior to the naked eye examination. In this overview article we present some non-invasive diagnostic techniques like total body photography, digital dermoscopy and confocal microscopy which in addition to dermoscopy assist the dermatologist in differentiating nevi from early melanomas.Non-melanoma skin cancer can be prevented by accurate sun protection. Early squamous cell carcinomas and basal cell carcinomas can be treated either invasively or non-invasively with excellent prognosis.

  18. Early Child Care In France

    Science.gov (United States)

    David, Myriam; Lezine, Irene

    1974-01-01

    The present monograph describes in detail the history and current status of early child care in France and discusses it in the contexts of family and cultural realities and attitudes toward children and upbringing. (Ed)

  19. NASA Early Career Fellowship Program

    Science.gov (United States)

    Smith, H. D.

    2012-12-01

    The Early Career Fellowship program was established in 2005 to facilitate the integration of outstanding early career planetary science researchers into established research funding programs by providing tools and experience useful to maintain a successful research program. Executing a successful research program requires a few key elements such as: successful proposal writing; adequate (paid) research time; management of a laboratory; collaboration and networking; frequent and high-quality publications; and adequate start-up equipment funds. These elements may be particularly critical for early career researchers searching for a tenure- track or equivalent position. The Early Career Fellowship program recognizes the importance of these skills and provides extra funding and resources to begin a successful research program. For consideration into The Early Career Fellowship program, the candidate needs to be the P. I. or Science P.I. of a funded research proposal from one of the participating R&A program areas, be within 7 years of earning a PhD, hold a non-tenure track position, and indicate the early career candidacy when submitting the research proposal. If the research proposal is funded and the discipline scientist nominates the candidate as an early career fellow, the candidate is then considered a Fellow and eligible to propose for Step 2. Upon obtaining a tenure-track equivalent position the Fellow submits a Step 2 proposal for up to one hundred thousand dollars in start-up funds. Start-up funds may be used for salary; undergraduate and/or graduate research assistants; supplies and instrument upgrades; travel to conferences, meetings, and advisory groups; time and travel for learning new skills; publication page charges; books and journal subscriptions; computer time and/or specialized software; and other justified research-specific needs. The early career fellowship program provides resources that a more established scientist would have acquired allowing

  20. Epigenetics of Early Child Development

    Directory of Open Access Journals (Sweden)

    Chris eMurgatroyd

    2011-04-01

    Full Text Available Comprehensive clinical studies show that adverse conditions in early life can severely impact the developing brain and increase vulnerability to mood disorders later in life. During early postnatal life the brain exhibits high plasticity which allows environmental signals to alter the trajectories of rapidly developing circuits. Adversity in early life is able to shape the experience-dependent maturation of stress-regulating pathways underlying emotional functions and endocrine responses to stress, such as the hypothalamo-pituitary-adrenal (HPA system, leading to long-lasting altered stress responsivity during adulthood.To date, the study of gene-environment interactions in the human population has been dominated by epidemiology. However, recent research in the neuroscience field is now advancing clinical studies by addressing specifically the mechanisms by which gene-environment interactions can predispose individuals towards psychopathology. To this end, appropriate animal models are being developed in which early environmental factors can be manipulated in a controlled manner. Here we will review recent studies performed with the common aim of understanding the effects of the early environment in shaping brain development and discuss the newly developing role of epigenetic mechanisms in translating early life conditions into long-lasting changes in gene expression underpinning brain functions. Particularly, we argue that epigenetic mechanisms can mediate the gene-environment dialogue in early life and give rise to persistent epigenetic programming of adult physiology and dysfunction eventually resulting in disease. Understanding how early life experiences can give raise to lasting epigenetic memories conferring increased risk for mental disorders, how they are maintained and how they could be reversed, is increasingly becoming a focus of modern psychiatry and should pave new guidelines for timely therapeutic interventions.

  1. Influence of energy and nutrient supply pre and post partum on performance of multiparous Simmental, Brown Swiss and Holstein cows in early lactation.

    Science.gov (United States)

    Gruber, L; Urdl, M; Obritzhauser, W; Schauer, A; Häusler, J; Steiner, B

    2014-01-01

    A study was conducted to evaluate the effects of pre partum (PRE) and post partum (POST) dietary energy and nutrient supply (E) and their interactions on feed intake, performance and energy status in dairy cows of three breeds. In this experiment, the effects of three energy and nutrient supply levels (low (L), medium (M), high (H)), both pre-calving and post-calving, were investigated, using a 3×3 factorial arrangement of treatments. In both phases (84 days pre- and 105 days post-calving) E levels applied to a total of 81 multiparous cows of breeds Simmental (SI), Brown Swiss (BS) and Holstein-Friesian (HF; n=27 for each breed), were 75%, 100% and 125% of recommendations of the German Society of Nutrition Physiology (GfE). Dry matter intake (DMI) was restricted, if energy intake exceeded target values. Pre partum DMI and energy intake were different as designed, liveweight and body condition score (BCS) of SI cows were higher, but EB was lower, compared to BS and HF cows. Milk yield and composition were influenced by all three main experimental factors (EPRE, EPOST, breed). Energy-corrected milk yield was 25.6, 28.6 and 30.1 kg/day for LPRE, MPRE and HPRE as well as 21.5, 30.1 and 32.6 kg/day for LPOST, MPOST and HPOST, respectively. Numerically, only for milk protein content the interactions EPRE×EPOST and EPRE×breed reached significance. Impact of energy supply pre-calving was more pronounced when cows had lower energy supply post-calving and vice versa. On the other hand, milk yield response of cows to energy supply above requirements was greater for cows that were fed on a low energy level pre partum. Impact of energy level pre partum was higher for HF cows, showing that their milk production relies to a greater extent on mobilization of body reserves. Increasing energy supply pre partum led to a more negative energy balance post partum, mainly by increasing milk yield and content, whereas feed intake was slightly reduced. Increasing energy supply post

  2. Early Learner Engagement in the Clinical Workplace

    NARCIS (Netherlands)

    Chen, H.C.

    2015-01-01

    Introduction Recent calls for medical education reform advocate for the integration of knowledge with clinical experience through early clinical immersion. Yet, early learners rarely are invited to participate in workplace activities and early clinical experiences remain largely observational.

  3. Early childhood intervention : rationale, timing, and efficacy

    OpenAIRE

    Orla Doyle; Richard E. Tremblay; Colm Harmon; James J. Heckman

    2007-01-01

    This paper provides a brief review of the economic rationale for investing in early childhood. It discusses the optimal timing of intervention, with reference to recent work in developmental neuroscience, and asks how early is early? It motivates the need for early intervention by providing an overview of the impact of adverse factors during the antenatal and early childhood period on outcomes later in life. Early childhood interventions, even poorly designed ones, are costly to implement,...

  4. [Early attention to learning disabilities].

    Science.gov (United States)

    Millá, M G

    2006-02-13

    In the early stages of their development, children acquire the skills and knowledge that provide them with the foundations on which they will later add what they learn at school, including skills such as reading, writing and mathematics. The presence of learning difficulties at the infantile stage can affect the development of these academic skills during the period of compulsory schooling. Some children show learning difficulties in their earliest years. Early learning difficulties refer specifically to those problems that occur in the time between birth and the age of six and which reduce the chances of accomplishing the skills and knowledge that are typically acquired during the stage of infancy. There is a correlation between these problems and difficulties linked to cognition, to attention, perception and memory processes, to language skills involving both comprehension and expression, and to visuospatial processing. Their aetiology involves neuropsychological, social and cultural factors, as well as others that derive from the actual learning processes themselves. Following an interdisciplinary model using development scales, psychometric tests and neurodevelopmental monitoring will allow an early diagnosis to be reached. The intervention will be carried out in the medical, social, educational and family areas, and will focus on the aspects that favour maturing, development and the learning of curricular material. The new socio-educational scenario makes it necessary to attend to early learning difficulties in infants' education. Prevention and early attention offer guidelines and strategies to deal with them in a satisfactory manner.

  5. early bolting in short days

    Science.gov (United States)

    Gómez-Mena, Concepción; Piñeiro, Manuel; Franco-Zorrilla, José M.; Salinas, Julio; Coupland, George; Martínez-Zapater, José M.

    2001-01-01

    The time of flowering in Arabidopsis is controlled by multiple endogenous and environmental signals. Some of these signals promote the onset of flowering, whereas others repress it. We describe here the isolation and characterization of two allelic mutations that cause early flowering and define a new locus, EARLY BOLTING IN SHORT DAYS (EBS). Acceleration of flowering time in the ebs mutants is especially conspicuous under short-day photoperiods and results from a reduction of the adult vegetative phase of the plants. In addition to the early flowering phenotype, ebs mutants show a reduction in seed dormancy, plant size, and fertility. Double mutant analysis with gibberellin-deficient mutants indicates that both the early-flowering and the precocious-germination phenotypes require gibberellin biosynthesis. Analysis of the genetic interactions among ebs and several mutations causing late flowering shows that the ft mutant phenotype is epistatic over the early flowering of ebs mutants, suggesting that the precocious flowering of ebs requires the FT gene product. Finally, the ebs mutation causes an increase in the level of expression of the floral homeotic genes APETALA3 (AP3), PISTILLATA (PI), and AGAMOUS (AG) and partially rescues the mutant floral phenotype of leafy-6 (lfy-6) mutants. These results suggest that EBS participates as a negative regulator in developmental processes such as germination, flowering induction, and flower organ specification. PMID:11340178

  6. Costs of jasmonic acid induced defense in aboveground and belowground parts of corn (Zea mays L.).

    Science.gov (United States)

    Feng, Yuanjiao; Wang, Jianwu; Luo, Shiming; Fan, Huizhi; Jin, Qiong

    2012-08-01

    Costs of jasmonic acid (JA) induced plant defense have gained increasing attention. In this study, JA was applied continuously to the aboveground (AG) or belowground (BG) parts, or AG plus BG parts of corn (Zea mays L.) to investigate whether JA exposure in one part of the plant would affect defense responses in another part, and whether or not JA induced defense would incur allocation costs. The results indicated that continuous JA application to AG parts systemically affected the quantities of defense chemicals in the roots, and vice versa. Quantities of DIMBOA and total amounts of phenolic compounds in leaves or roots generally increased 2 or 4 wk after the JA treatment to different plant parts. In the first 2 wk after application, the increase of defense chemicals in leaves and roots was accompanied by a significant decrease of root length, root surface area, and root biomass. Four weeks after the JA application, however, no such costs for the increase of defense chemicals in leaves and roots were detected. Instead, shoot biomass and root biomass increased. The results suggest that JA as a defense signal can be transferred from AG parts to BG parts of corn, and vice versa. Costs for induced defense elicited by continuous JA application were found in the early 2 wk, while distinct benefits were observed later, i.e., 4 wk after JA treatment.

  7. A longitudinal twin study on the association between ADHD symptoms and reading.

    Science.gov (United States)

    Greven, Corina U; Rijsdijk, Frühling V; Asherson, Philip; Plomin, Robert

    2012-03-01

    Attention deficit hyperactivity disorder (ADHD) and reading disability commonly co-occur because of shared genetic risk factors. However, the stability and change of these genetic influences and the predictive relationships underlying this association longitudinally remain unclear. ADHD symptoms and reading were assessed as continuous dimensions in a UK general population sample of approximately 7,000 twin pairs. Parent ratings of ADHD symptoms and teacher ratings of reading were obtained at two ages: middle childhood (ages 7-8 years) and early adolescence (ages 11-12 years). Cross-lagged quantitative genetic analyses were applied. ADHD symptoms and reading significantly predicted each other over time. However, ADHD symptoms were a significantly stronger predictor of reading than vice versa. Inattentive and hyperactive-impulsive symptoms of ADHD both contributed to the prediction of reading, but inattentiveness was a significantly stronger predictor. Furthermore, ADHD symptoms and reading were highly heritable, and their association was primarily attributable to shared genetic influences. Despite notable genetic innovation for each trait, genetic factors involved in the association of ADHD symptoms and reading over time were highly stable. ADHD symptoms may put children at increased risk for reading problems and vice versa. Moreover, enduring genetic mechanisms appear to be important in the association of ADHD symptoms and reading over time. © 2011 The Authors. Journal of Child Psychology and Psychiatry © 2011 Association for Child and Adolescent Mental Health.

  8. Early Literacy and Early Numeracy: The Value of Including Early Literacy Skills in the Prediction of Numeracy Development

    Science.gov (United States)

    Purpura, David J.; Hume, Laura E.; Sims, Darcey M.; Lonigan, Cristopher J.

    2011-01-01

    The purpose of this study was to examine whether early literacy skills uniquely predict early numeracy skills development. During the first year of the study, 69 3- to 5-year-old preschoolers were assessed on the Preschool Early Numeracy Skills (PENS) test and the Test of Preschool Early Literacy Skills (TOPEL). Participants were assessed again a…

  9. What is 'early onset dementia'?

    Science.gov (United States)

    Miyoshi, Koho

    2009-06-01

    There are two types of dementia with early onset: (i) presenile dementias; and (ii) senile dementias with early onset. Most patients who develop dementia before 65 years of age have Alzheimer's disease (AD). The remainder are likely to have vascular dementia (VaD), frontotemporal dementia, head injury, alcohol intoxication, or metabolic disorder. Presenile dementias, caused by frontotemporal lobar degeneration, progressive supranuclear palsy, and corticobasal degeneration, usually occur in patients of presenile and are rarely seen in patients of senile age. Although the factors responsible for the accelerated onset of the illness are not fully known, genetic abnormalities appear to be important in some types of presenile dementia, such as frontotemporal dementia with parkinsonism linked to chromosome 17. Conversely, senile dementias such as sporadic AD and VaD commonly occur in patients of senile age. These disorders may also occur in patients of presenile age, although less frequently. Alzheimer's disease was originally classified as a 'presenile dementia'. Since the 1980s, 'senile dementia of Alzheimer type' (SDAT) and 'Alzheimer's disease' have been considered to belong to the same pathological entity and both are now known as 'dementia of Alzheimer's type (DAT)' or merely 'Alzheimer's disease'. Rapid progression of cognitive impairment with neuropsychological syndromes and neurological symptoms has been considered a characteristic of early onset AD. However, recently, neurological symptoms such as spastic paraparesis, seizures, and myoclonic convulsions have been reported to occur infrequently in early onset AD, although language problems and visuospatial dysfunctions are common. There are at least three dominant genes that have been identified in cases of familial Alzheimer's disease with early onset, namely the amyloid precursor gene (APP), and the genes encoding presenilin 1 (PSEN1) and presenilin 2 (PSEN2). Therefore, genetic abnormalities are important

  10. Early intervention as a catalyst for effective early childhood ...

    African Journals Online (AJOL)

    Early childhood intervention is an essential contributor and catalyst for the development of a culture of positive attitudes towards children with disabilities in a country like Ghana. ... This would provide mutual benefits for children with disabilities, parents and families, educators and professionals and the society at large.

  11. Overdiagnosis in early detection programs.

    Science.gov (United States)

    Davidov, Ori; Zelen, Marvin

    2004-10-01

    Overdiagnosis refers to the situation where a screening exam detects a disease that would have otherwise been undetected in a person's lifetime. The disease would have not have been diagnosed because the individual would have died of other causes prior to its clinical onset. Although the probability of overdiagnosis is an important quantity for understanding early detection programs it has not been rigorously studied. We analyze an idealized early detection program and derive the mathematical expression for the probability of overdiagnosis. The results are studied numerically for prostate cancer and applied to a variety of screening schedules. Our investigation indicates that the probability of overdiagnosis is remarkably high.

  12. The Early Origins of Autism.

    Science.gov (United States)

    Constantino, John N; Marrus, Natasha

    2017-07-01

    Autism spectrum disorders (ASDs) are neurodevelopmental disorders whose core features of impaired social communication and atypical repetitive behaviors and/or restrictions in range of interests emerge in toddlerhood and carry significant implications at successive stages of development. The ability to reliably identify most cases of the condition far earlier than the average age of diagnosis presents a novel opportunity for early intervention, but the availability of such an intervention is disparate across US communities, and its impact is imperfectly understood. New research may transform the clinical approach to these conditions in early childhood. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Shocks in the Early Universe.

    Science.gov (United States)

    Pen, Ue-Li; Turok, Neil

    2016-09-23

    We point out a surprising consequence of the usually assumed initial conditions for cosmological perturbations. Namely, a spectrum of Gaussian, linear, adiabatic, scalar, growing mode perturbations not only creates acoustic oscillations of the kind observed on very large scales today, it also leads to the production of shocks in the radiation fluid of the very early Universe. Shocks cause departures from local thermal equilibrium as well as create vorticity and gravitational waves. For a scale-invariant spectrum and standard model physics, shocks form for temperatures 1  GeVUniverse as early as 10^{-30}  sec after the big bang.

  14. Early Development Economics Debates Revisited

    OpenAIRE

    Alacevich, Michele

    2007-01-01

    Development economics in its early years created the image of a fierce fight between advocates of contrasting theories or approaches- "balanced growth" vs. "unbalanced growth" or "program loans" vs. "project loans." This view has the merit to highlight such conflicts in great detail; yet it fails to take into account the reality of development economics as it was practiced in the field. Th...

  15. Electromigration early resistance increase measurements

    NARCIS (Netherlands)

    Niehof, J.; Flinn, P.A.; Maloney, T.J.

    1993-01-01

    An early resistance change measurement set-up, using an AC bridge technique, has been developed, and measurements have been performed. Large sample-to-sample variations occur. The characteristic time for the resistance change curve is shorter for resistance increase (under current stress) than for

  16. Early Childhood Inclusion in Israel

    Science.gov (United States)

    Al-Yagon, Michal; Aram, Dorit; Margalit, Malka

    2016-01-01

    This article describes conceptual aspects, current policies and practices, and research representing the Israeli perspective regarding early childhood inclusion (ECI) at preschool ages (3-6 years). We review legislative, historical, attitudinal, philosophical, practical, empirical, and cultural issues regarding ECI in Israel. Finally, we focus on…

  17. Suicidal Behavior among Early Adolescents.

    Science.gov (United States)

    Gover, F. Jill

    There is a great deal of concern about teenage suicide. This study obtained a prevalence rate of suicidal behaviors among non-psychiatric early adolescents (ages 11-16) and investigated personal and family variables that may characterize the young teenagers who report varying degrees of suicidal behavior. A self-report questionnaire was…

  18. Tucson Early Education Psychological Services.

    Science.gov (United States)

    Bergan, John R.; And Others

    This report describes the Tucson Early Education Psychological Services (TEEPS) program during its third year of operation. TEEPS is based on the position that the quality of psychological services in the public schools can be increased by establishing educational systems in which the functions of psychology in education are embodied in system…

  19. Physical Education in Early Childhood

    Science.gov (United States)

    Stork, Steve; Sanders, Stephen W.

    2008-01-01

    This article examines the incidence and quality of physical activity instruction during early childhood. Although the positive effect of physical activity on the cognitive, social, and physical development of young children is generally acknowledged, there is little emphasis nationally on ensuring appropriate physical educational experiences…

  20. ABCDEs of ICU: Early mobility.

    Science.gov (United States)

    Dang, Stephanie L

    2013-01-01

    The intensive care unit (ICU) provides a critical level of care to medically unstable patients. Patients need intensive monitoring and treatment that may require emergency interventions. The vulnerability and complexity of the ICU unintentionally creates an environment that limits and poorly defines the intervention of early mobility in the unstable critically ill patients. The short- and long-term effects of immobility and bed rest increase acute complications, the length of stay in the ICU and hospital, and mortality and morbidity rates. According to current research, instituting early mobility programs can improve patient outcomes. Current research has demonstrated the safety and feasibility of the initiation of early mobility programs in the critically ill. The benefits to patients enhance recovery of functional exercise capacity, weaning outcomes, self-perceived functional status, and muscle force and strength. Consequently, patient's length of stay in the ICU and in hospital decreases and improves health outcomes. The scope of practice for nurses and other health care providers should guide by evidenced-based research to reduce complications and enhance patient outcomes. Further research is necessary to establish and institute policies and protocols on early mobility programs in the ICU to direct patient care. The role of the clinical nurse specialist can contribute by conducting evidence-based research, educating health care providers and patients, and implementing protocols. The hope is to change the culture of the ICU for the better.

  1. The Early Years: Mixing Materials

    Science.gov (United States)

    Ashbrook, Peggy

    2017-01-01

    Engaging children's interest, inspiring active exploration of materials, and fostering cooperation between children and adults is the best way to promote the construction of knowledge. Some popular early childhood activities can be expanded to provide experiences and time for children to build on their prior knowledge. This column discusses…

  2. Early Learning Theories Made Visible

    Science.gov (United States)

    Beloglovsky, Miriam; Daly, Lisa

    2015-01-01

    Go beyond reading about early learning theories and see what they look like in action in modern programs and teacher practices. With classroom vignettes and colorful photographs, this book makes the works of Jean Piaget, Erik Erikson, Lev Vygotsky, Abraham Maslow, John Dewey, Howard Gardner, and Louise Derman-Sparks visible, accessible, and easier…

  3. Early Children's Literature and Aging

    Science.gov (United States)

    McGuire, Sandra L.

    2016-01-01

    Increased longevity is a worldwide phenomenon placing emphasis on the need for preparation for life's later years. Today's children will be the older adults of tomorrow. A resource that can help to educate them about aging and prepare them for the long life ahead is early children's literature (Preschool-Primary). This literature can provide…

  4. SEL Interventions in Early Childhood

    Science.gov (United States)

    McClelland, Megan M.; Tominey, Shauna L.; Schmitt, Sara A.; Duncan, Robert

    2017-01-01

    Young children who enter school without sufficient social and emotional learning (SEL) skills may have a hard time learning. Yet early childhood educators say they do not get enough training to effectively help children develop such skills. In this article, Megan McClelland, Shauna Tominey, Sara Schmitt, and Robert Duncan examine the theory and…

  5. HPLC: Early and Recent Perspectives.

    Science.gov (United States)

    Karger, Barry L.

    1997-01-01

    Provides a perspective on what it was like in the early days of high-performance liquid chromatography (HPLC) and several of the key developments. Focuses on the advances in HPLC generally, and more specifically for the biological sciences, that were necessary for the method to reach the preeminent stage of today. Contains 20 references. (JRH)

  6. Defeating cancer with early detection

    CERN Multimedia

    2003-01-01

    A meeting of scientists and industry experts will hold an open review of the Three Dimension Complete Body Screening System (3D-CBS) on the 1st of July 2003. This new imaging technlogy is potentially powerful and safe enough to offer routine screening of healthy patients for early signs of cancer (1 page).

  7. Early identification of communication problems.

    Science.gov (United States)

    Gale, M; Holloway, K; Roulstone, S

    1994-10-01

    Questions have been raised about the effectiveness of routine early screening of children's speech development. Mary Gale et al describe an innovative package which can be used by health visitors and parents to ensure they correctly identify those children needing referral for specialist intervention.

  8. Early Childhood Intervention in China

    Science.gov (United States)

    Zheng, Yuzhu; Maude, Susan P.; Brotherson, Mary Jane

    2015-01-01

    With rapid economic development and increasing awareness of the importance of early childhood intervention (ECI), China is re-examining its social and educational practices for young children with disabilities. This re-examination may have a significant impact on young children with disabilities in China. It may also set an example for other…

  9. Early-delayed radiation rhombencephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Nightingale, S.; Dawes, P.J.D.K.; Cartlidge, N.E.F. (Royal Victoria Infirmary, Newcastle upon Tyne (UK); Newcastle upon Tyne Univ. (UK). Newcastle General Hospital)

    1982-03-01

    A 37-year-old woman developed an early-delayed rhombencephalopathy 7 weeks after completing a course of radiotherapy to a glomus jugulare tumour. The clinical features, comprising nystagmus, skew strabismus, unilateral facial weakness, dysarthria and ataxia, are compared with four previously reported patients with this syndrome.

  10. Early Signs of Entrepreneurial Giftedness

    Science.gov (United States)

    Shavinina, Larisa V.

    2008-01-01

    Although successful entrepreneurship is important for the economic prosperity of any society, one should acknowledge that entrepreneurial giftedness is terra incognita from a research viewpoint. This article analyzes early manifestations of entrepreneurial giftedness in the cases of Richard Branson, Michael Dell, and Bill Gates and thus opens a…

  11. Uganda Early Generation Seed Study

    NARCIS (Netherlands)

    Mastenbroek, A.; Ntare, Bonny

    2016-01-01

    One of the major bottlenecks limiting farmers’ access to good quality seed for food crops in Uganda is the shortage of early generation seed (EGS - breeder and foundation) to produce sufficient quantities of certified and/or quality declared) to satisfy the needs of farmers. A national study was

  12. Early Childhood Inclusion in Australia

    Science.gov (United States)

    Kemp, Coral R.

    2016-01-01

    From the introduction of early intervention services in Australian in the mid-1970s, the families of children with intellectual and multiple disabilities have been encouraged to enroll their children in local preschools and childcare centers. Children with disabilities have also accessed a range of alternatives to full inclusion, such as reverse…

  13. [Early career of Michael Sendivogius].

    Science.gov (United States)

    Prinke, Rafał T

    2012-01-01

    One of the most influential alchemical authors of the early modern period was Michael Sendivogius whose early life is shrouded in mystery. He may be labelled the most famous Polish scientific writer between Copernicus and Marie Skłodowska-Curie, but because of the difficulties involved in researching the biography of any alchemist, there has been relatively little interest in him among Polish historians. The early work of Roman Bugaj (author of the still fundamental monograph) and Włodzimierz Hubicki (who made his research available to the international community) has been continued only by the English-born Zbigniew Szydło and the author of this article. The roots of many legends about Sendivogius were three mid-17th century short biographies, none of which is trustworthy, so it is crucial to verify the received myth and the version constructed in the 1960's and 1970's with primary sources and evidence from the recent "new historiography of alchemy". The present article examines them in the light of newly discovered sources and reinterpretation of the old ones. The genealogy of the Sedzimir family is discussed at length to show that Sendivogius most probably was not its member but only a pretender in order to assume (or prove) the status of a nobleman. Several possible hypotheses about his origins are presented. He is known to have studied at three universities (Leipzig, Vienna and Altdorf) but authors of early panegyrics dedicated to Sendivogius list more universities which he may have attended. The most interesting is that of Cambridge, listed as the first one, because practically no Poles or Czechs went there at the time. Finally, his marriage to Veronica Stiebar, a wealthy widow of a Franconian knightly family, and her interesting family relationships (links to Erasmus, Camerarius, Paracelsus and the original Doctor Faustus) are discussed. The period covered is that before Sendivogius moved to Prague in about 1597, having already been a courtier of Rudolf II

  14. Early lunar geology and geophysics

    Science.gov (United States)

    Garrick-Bethell, Ian

    2009-06-01

    Despite a number of human and robotic missions to the Moon, there are still important unanswered questions about its early evolution, and how it came to be the object we observe today. Here we use observational, experimental, and theoretical techniques to examine three important events that took place early in lunar history and have left a lasting signature. The first event is the formation of the largest basin on the Moon, the South Pole-Aitken Basin. We develop a systematic method to define the previously unknown boundaries of this degraded structure and quantify its gross shape. We also combine a number of remote sensing data sets to constrain the origin of heat producing elements in its interior. The second event we examine is the evolution of the lunar orbit, and the coupling between the Moon's early geophysical properties and the growth of orbital eccentricity. We use analytical models for tidal deformations and orbit evolution to show that the shape of the Moon suggests its early orbit was highly eccentric. However, we are also able to explain the presently high eccentricity entirely by traditional, secular tidal growth while the early Moon was hot. The third event we examine is the magnetization of lunar samples. We perform extensive paleomagnetic measurements of an ancient, deep-seated lunar sample, and determine that a long-lived magnetic field like that of a core dynamo is the most plausible explanation for its magnetic remanence. In sum, the earliest portion of lunar history has been largely obscured by later geologic events, but a great deal can still be learned from this formative epoch. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  15. Early care in children with neurodevelopmental disorders

    Directory of Open Access Journals (Sweden)

    Jacqueline Ponce-Meza

    2017-04-01

    Full Text Available The article analyzes the importance of early care in child development, guiding a neuropsychological perspective of development. The early care model seeks to refer to the set of interventions aimed at children and their work in conjunction with a multidisciplinary team. It presents recommendations for the implementation of programs that allow early intervention in the early years, so that the process of care for the affected children can be optimized by the different early developmental and learning alterations.

  16. Penatalaksanaan early childhood caries Management of early childhood caries

    OpenAIRE

    Fajriani Fajriani; Hendrastuty Handayani

    2011-01-01

    Early childhood caries (ECC), also known as milk bottle caries is a syndrome of severe tooth decay, occurs in infants and children, is an infectious disease that develops rapidly and lead to health problems in children. This syndrome can be caused by inappropriate use of bottles. Most cases of untreated ECC to children aged 20 months. At this stage many children need serious treatment, because this will result in trauma to both the children and parents. The most common treatment E...

  17. Pompe Disease: Early Diagnosis and Early Treatment Make a Difference

    Directory of Open Access Journals (Sweden)

    Yin-Hsiu Chien

    2013-08-01

    Full Text Available Pompe disease (glycogen storage disease type II or acid maltase deficiency is a lysosomal disorder in which acid α-glucosidase (GAA deficiencies lead to intralysosomal accumulation of glycogen in all tissues; most notably in skeletal muscles. Both the patient's age at the onset of Pompe disease symptoms and the rate of deterioration caused by the disease can vary considerably. In classical infant-onset Pompe disease (IOPD, symptoms start very early in life, and death occurs soon afterward if the disease remains untreated. In later-onset Pompe disease, symptoms are slower to appear, and patients often progress to wheelchair confinement and eventual respiratory failure. A diagnosis can be made by screening for GAA in dried blood samples, followed either by GAA assessment in lymphocytes or in fibroblasts or by the genetic analysis of mutations. Treatment by enzyme replacement therapy (ERT with alglucosidase alfa was approved for human use in 2006. In classical IOPD, treatment significantly lengthens survival and improves motor development and cardiac function. The sooner ERT begins, the better are the results. Newborn screening aims to take advantage of different technologies for diagnosing and treating newborns early on and it yields better outcomes. However, newborns diagnosed early and other long-term survivors may encounter fresh problems, making up a new phenotype of IOPD patients. Further modifications of the treatment, such as a decrease in immune responses to ERT, a higher dosage, a better uptake formulation, and gene therapy delivered locally or systemically are being explored.

  18. Famines in Africa: is early warning early enough?

    Directory of Open Access Journals (Sweden)

    Jeeyon Janet Kim

    2012-06-01

    Full Text Available Following the second Sahelian famine in 1984–1985, major investments were made to establish Early Warning Systems. These systems help to ensure that timely warnings and vulnerability information are available to decision makers to anticipate and avert food crises. In the recent crisis in the Horn of Africa, alarming levels of acute malnutrition were documented from March 2010, and by August 2010, an impending food crisis was forecast. Despite these measures, the situation remained unrecognised, and further deteriorated causing malnutrition levels to grow in severity and scope. By the time the United Nations officially declared famine on 20 July 2011, and the humanitarian community sluggishly went into response mode, levels of malnutrition and mortality exceeded catastrophic levels. At this time, an estimated 11 million people were in desperate and immediate need for food. With warnings of food crises in the Sahel, South Sudan, and forecast of the drought returning to the Horn, there is an immediate need to institutionalize change in the health response during humanitarian emergencies. Early warning systems are only effective if they trigger an early response.

  19. A Study of the Relationship between Early Childhood Program Attributes and Early Childhood Reading Achievement

    Science.gov (United States)

    Washington, Novella M.

    2012-01-01

    This quantitative correlational study focuses on the relationship between early childhood program attributes and early childhood reading success. Data will be gathered from early childhood sites with grades prekindergarten through second grade in which early childhood program attributes exist and early childhood reading is measured by the…

  20. Early Management and Fluid Resuscitation

    Directory of Open Access Journals (Sweden)

    Kaya Yorgancı

    2011-07-01

    Full Text Available Initial management of severely burned patient is similar with a trauma victim. Determination of airway patency, evaluation of respiration and circulation, early recognition of concomitant trauma has vital importance in burn patients. In the early phase, mortality mainly depends on missed or un-treated severe injuries or pathologies, but not burn injury itself.In patients that have TBSA greater than 15 %, fluid resuscitation should be started. In the first 24 hours, crystalloid solutions should be preferred. .Several formulas can guide fluid resuscitation; however the amount of fluid that is given to the patient should be individualized according to the patient’s need. (Journal of the Turkish Society Intensive Care 2011; 9 Suppl: 7-10

  1. Robert Abbe: early American brachytherapist.

    Science.gov (United States)

    Aronowitz, Jesse N

    2012-01-01

    To assess Robert Abbe's career and contributions to brachytherapy, in the context of the work of contemporary European and American investigators. Examination of his lectures and journal articles, as well as contemporaneous newspaper accounts, textbooks, and archival material. Although not the first American to apply radium therapeutically, Robert Abbe was among the earliest to acquire and systematically use a clinically significant quantity. He replicated early European experimental and clinical work, and published a large series of cases treated with generally favorable results. Abbe was the first American to emphasize the role of radiobiology in optimizing therapeutic ratio. His eloquence and stature helped legitimize the new therapeutic modality. Robert Abbe was probably the nation's most influential early brachytherapist. Copyright © 2012 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  2. Nanotechnology for Early Cancer Detection

    Directory of Open Access Journals (Sweden)

    Joon Won Park

    2010-01-01

    Full Text Available Vast numbers of studies and developments in the nanotechnology area have been conducted and many nanomaterials have been utilized to detect cancers at early stages. Nanomaterials have unique physical, optical and electrical properties that have proven to be very useful in sensing. Quantum dots, gold nanoparticles, magnetic nanoparticles, carbon nanotubes, gold nanowires and many other materials have been developed over the years, alongside the discovery of a wide range of biomarkers to lower the detection limit of cancer biomarkers. Proteins, antibody fragments, DNA fragments, and RNA fragments are the base of cancer biomarkers and have been used as targets in cancer detection and monitoring. It is highly anticipated that in the near future, we might be able to detect cancer at a very early stage, providing a much higher chance of treatment.

  3. Early intervention services in psychosis

    DEFF Research Database (Denmark)

    Csillag, Claudio; Nordentoft, Merete; Mizuno, Masafumi

    2016-01-01

    AIM: Early intervention (EI) in psychosis is a comprehensive and evidence-based approach aimed at detection and treatment of psychotic symptoms in their early stages. This paper presents core features and noteworthy aspects of the evidence basis and limitations of EI, the importance of programme ....... Wider dissemination of EI services will probably benefit from better integration of potential funders, promotion of joint targets and shared financial or budgetary incentives....... overcome these difficulties. CONCLUSIONS: Funding for mental health in general and for EI services appears low relative to need. One key argument for better funding for EI can be found in its favourable cost-effectiveness, but not all stakeholders beyond mental health administrators are aware of this...

  4. Early stages of Ostwald ripening.

    Science.gov (United States)

    Shneidman, Vitaly A

    2013-07-01

    The Becker-Döring (BD) nucleation equation is known to predict a narrow double-exponential front (DEF) in the distribution of growing particles over sizes, which is due to early transient effects. When mass conservation is included, nucleation is eventually exhausted while independent growth is replaced by ripening. Despite the enormous difference in the associated time scales, and the resulting demand on numerics, within the generalized BD model the early DEF is shown to be crucial for the selection of the unique self-similar Lifshitz-Slyozov-Wagner asymptotic regime. Being preserved till the latest stages of growth, the DEF provides a universal part of the initial conditions for the ripening problem, regardless of the mass exchange mechanism between the nucleus and the matrix.

  5. Early BHs: simulations and observations

    Science.gov (United States)

    Cappelluti, Nico; di-Matteo, Tiziana; Schawinski, Kevin; Fragos, Tassos

    We report recent investigations in the field of Early Black Holes. We summarize recent theoretical and observational efforts to understand how Black Holes formed and eventually evolved into Super Massive Black Holes at high-z. This paper makes use of state of the art computer simulations and multiwavelength surveys. Although non conclusive, we present results and hypothesis that pose exciting challenges to modern astrophysics and to future facilities.

  6. Markers of Early Vascular Ageing.

    Science.gov (United States)

    Kotsis, Vasilios; Antza, Christina; Doundoulakis, Ioannis; Stabouli, Stella

    2017-01-01

    Cardiovascular damage is clinically manifested as coronary artery disease, heart failure, stroke and peripheral artery disease. The prevalence of these adverse conditions is higher with advancing age. Although many patients present cardiovascular damage late in their life, it is common to see patients with early atherosclerosis in cardiovascular intensive care units at ages lower than 50 years in men and 55 for women. In this review of the literature we identified risk factors of early vascular damage. The classic risk factors such as age, gender, diabetes mellitus, dyslipidemia, smoking, alcohol, hypertension, obesity, family history and newer biomarkers such as hs-CRP, folic acid, homocysteine, fibrinogen are neither strong nor predictive of the individual patient's risk to present early cardiovascular disease. All these risk factors have been used to propose risk scores for possible future events but we still lack a single strong marker indicating new onset of disease that will predict the future independently of the classical factors. The role of vascular imaging techniques to identify patients with subclinical atherosclerotic vascular damage before clinical disease, including the effect of known and unknown risk factors on the vascular tree, seems to be very important for intensifying preventive measures in high risk patients. Early arteriosclerosis measured from pulse wave velocity is associated with reduced arterial elasticity and is associated with future cardiovascular events. Vascular measurements may better represent the continuum of cardiovascular disease from a young healthy to an aged diseased vessel that is going to produce adverse clinical events. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  7. Prevention of early childhood caries.

    Science.gov (United States)

    Ismail, A I

    1998-01-01

    This paper reviews the methods used for the prevention of early childhood caries (ECC). The education of mothers or caregivers to promote healthy dietary habits in infants has been the main strategy used for the prevention of ECC. This review found that education has a modest impact on the development of ECC. While education should be promoted especially in high risk communities and population groups (low-income families and native populations), it should not be the only preventive strategy of ECC. Early screening for signs of caries development, starting from the first year of life, could identify infants and toddlers who are at risk of developing ECC and assist in providing information to parents about how to promote oral health and prevent the development of tooth decay. High risk children include those with early signs of ECC, poor oral hygiene, limited exposure to fluorides, and frequent exposure to sugary snacks and drinks. These children should be targeted with a professional preventive program that includes fluoride varnish application, fluoridated dentifrices, fluoride supplements, sealants, diet counseling, and chlorhexidine. Prevention of ECC also requires addressing the social and economic factors that face many families where ECC is endemic.

  8. Early science results from SOFIA

    Science.gov (United States)

    Young, Erick T.; Herter, Terry L.; Güsten, Rolf; Dunham, Edward W.; Becklin, Eric E.; Marcum, Pamela M.; Krabbe, Alfred; Andersson, B.-G.; Reach, William T.; Zinnecker, Hans

    2012-09-01

    SOFIA, the Stratospheric Observatory for Infrared Astronomy, is an airborne observatory with a 2.7-m telescope that is under development by NASA and the German Aerospace Center DLR. From late 2010 and through the end of 2011, SOFIA conducted a series of science demonstration flights, Early Science, using FORCAST (the Faint Object InfraRed Camera for the SOFIA Telescope), HIPO (the High-speed Imaging Photometer for Occultations), and GREAT (the German REceiver for Astronomy at Terahertz frequencies). Flying at altitudes as high as 13.7 km (45,000 ft), SOFIA operates above more than 99.8% of the water vapor in the Earth’s atmosphere, opening up most of the far-infrared and sub-millimeter parts of the spectrum. During Early Science, 30 science missions were flown with results in solar system astronomy, star formation, the interstellar medium, the Galactic Center, and extragalactic studies. Many of these investigations were conducted by the first group of SOFIA General Investigators, demonstrating the operation of SOFIA as a facility for the astronomical community. This paper presents some recent highlights from Early Science.

  9. Early pregnancy wastage: ethical considerations.

    Science.gov (United States)

    Benagiano, Giuseppe; Mori, Maurizio; Ford, Norman; Grudzinskas, Gedis

    2011-06-01

    Information on early embryo wastage is relevant for debating the status of human embryos. Two main points of view confront each other. Theists hold that human embryos should be treated as human persons from the moment of conception because, even accepting that human beings are the fruit of evolution, they are part of a divine project. Without a developmental event prior to which the human embryo could not be considered a human being, embryos should be regarded as if they were human subjects. After all, if one believes in the resurrection of the dead, it makes no difference at what stage one's life ends. Secularists oppose the idea of granting absolute value to human life from its beginning because early human embryos lack individuality and sentience. Personifying embryos is morally absurd because it would mean that countless human beings never had even the slightest chance to express their potential and, in the light of this catastrophic loss, one would expect early pregnancy wastage to have become an important research priority; this is not the case. In practical terms, most Western countries have legalized first-trimester abortion, de facto giving embryos a lower status than that of full person. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  10. Oxygen and Early Animal Evolution

    Science.gov (United States)

    Xiao, S.

    2012-12-01

    It is often hypothesized that the rise of animals was triggered by an increase in O2 levels in the atmosphere and oceans. However, this hypothesis is remarkably difficult to test, because the timing of animal divergences is poorly resolved, the physiology of early animals is often unknown, estimates of past pO2 levels come with large error bars, and causal relationships between oxygenation and animal evolution are difficult to establish. Nonetheless, existing phylogenetic, paleontological, and geochemical data indicate that the evolution of macroscopic animals and motile macrometazoans with energetically expensive lifestyles may be temporally coupled with ocean oxygenation events in the Ediacaran Period. Thus, it is plausible that ocean oxygenation may have been a limiting factor in the early evolution of macroscopic, complex, and metabolically aggressive animals (particularly bilaterian animals). However, ocean oxygenation and animal evolution were likely engaged in two-way interactions: Ediacaran oxygenation may have initially lifted a physiological barrier for the evolution of animal size, motility, and active lifestyles, but subsequent animal diversification in the Paleozoic may have also changed oceanic redox structures. Viewed in a broader context, the early evolutionary history of animals was contingent upon a series of events, including genetic preparation (developmental genetics), environmental facilitation (oceanic oxygenation), and ecological escalation (Cambrian explosion), but the rise of animals to ecological importance also had important geobiological impacts on oceanic redox structures, sedimentary fabrics, and global geochemical cycles.

  11. Linkages over time between adolescents' relationships with parents and friends.

    Science.gov (United States)

    De Goede, Irene H A; Branje, Susan J T; Delsing, Marc J M H; Meeus, Wim H J

    2009-11-01

    This 5-wave longitudinal study examines linkages over time between adolescents' perceptions of relationships with parents and friends with respect to support, negative interaction, and power. A total of 575 early adolescents (54.1% boys) and 337 middle adolescents (43.3% boys) participated. Path analyses mainly showed bidirectional associations between adolescents' perceptions of parent-adolescent relationships and friendships with a predominantly stronger influence from parent-adolescent relationships to friendships than vice versa in early to middle adolescence and an equal mutual influence in middle to late adolescence. The findings support the theoretical ideas that perceptions of relationships with parents generalize to perceptions of relationships with friends and that relationship skills and principles of adolescent friendships generalize to relationships with parents. Furthermore, the results indicate that the influence of parents decreases, whereas the influence of friends increases, and that both social worlds become equally important and overlapping towards late adolescence.

  12. Supporting Families through Early Intervention

    Directory of Open Access Journals (Sweden)

    Roy McConkey

    2003-09-01

    Full Text Available Internationally early intervention programmes for infants and preschoolers with disabilities have proved to be remarkably successful. In many countries, they began with teachers for visually impaired or hearing impaired children visiting the family home to teach parents how they could overcome the child's impairments. The logic of early intervention was inequitable. For example, the sooner children with visual impairments learnt to be independently mobile, then the greater their potential to learn and to kad an ordinary life. In time, this philosophy was extended to children with neurological and developmental delays, such as mental retardation, although success could be variable. In part, many different factors contributed to this variability: the form the interventions took, the extent of family involvement in the intervention and the lack of sensitivity of the measures used to assess a child's progress, to name but three. Perhaps the most extensive and intensive Early intervention schemes have been in the United States with their Head Start programmes. They were aimed at promoting the educational potential of preschoolers from deprived socio - economic backgrounds. Although the first phase of programmes had varying success, those in the second phase yielded impressive results which were mainly attributed to a greater focus on parental participation and links forged with the school system. Recently in developing countries, priority has been given to establishing early intervention as a means of creating new styles of family-based and community-based service in these countries in contrast to the hospital or institutional-services that were a legacy from a previous generation. Although formal evaluations are largely lacking, informal reports have been broadly enthusiastic. In sum, early intervention is no longer a new approach to developmental disabilities. It is an approach of proven effectiveness with children who have different impairments

  13. Early Childhood Special Education and Early Intervention Personnel Preparation Standards of the Division for Early Childhood: Field Validation

    Science.gov (United States)

    Cochran, Deborah C.; Gallagher, Peggy A.; Stayton, Vicki D.; Dinnebeil, Laurie A.; Lifter, Karin; Chandler, Lynette K.; Christensen, Kimberly A.

    2012-01-01

    Results of the field validation survey of the revised initial and new advanced Council for Exceptional Children (CEC) Division for Early Childhood (DEC) early childhood special education (ECSE)/early intervention (EI) personnel standards are presented. Personnel standards are used as part of educational accountability systems and in teacher…

  14. Early rehabilitation and participation in focus

    DEFF Research Database (Denmark)

    Pallesen, Hanne; Buhl, Inge; Roenn-Smidt, Helle

    2016-01-01

    Early neurorehabilitation is an interdisciplinary field. Thus, in order to eliminate unnecessary barriers for individuals with severe acquired brain injury in early rehabilitation, we need rehabilitation science that supports both quantitative and qualitative research methods. Participation can...

  15. Early rehabilitation and participation in focus

    DEFF Research Database (Denmark)

    Pallesen, Hanne; Buhl, Inge; Roenn-Smidt, Helle

    2016-01-01

    Early neurorehabilitation is an interdisciplinary field. Thus, in order to eliminate unnecessary barriers for individuals with severe acquired brain injury in early rehabilitation, we need rehabilitation science that supports both quantitative and qualitative research methods. Participation can b...

  16. International research in early childhood education

    National Research Council Canada - National Science Library

    2010-01-01

    "The journal of International Research in Early Childhood Education (IRECE) is an electronic peer-reviewed journal designed to provide an international forum for scholarship and research within the field of early childhood education...

  17. Early vocabulary inventory for Mandarin Chinese

    National Research Council Canada - National Science Library

    Hao, Meiling; Shu, Hua; Xing, Ailing; Li, Ping

    2008-01-01

    .... However, there have been no published CDI norms for Mandarin Chinese. Given the importance of large-scale comparative data sets for understanding the early childhood lexicon, we have developed an early vocabulary inventory for Mandarin...

  18. Early Parkinson's May Prompt Vision Problems

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_167131.html Early Parkinson's May Prompt Vision Problems Changes in sight could ... in vision may be an early sign of Parkinson's disease, researchers report. The neurodegenerative condition is caused ...

  19. Early detection of first-episode psychosis

    DEFF Research Database (Denmark)

    Larsen, Tor K; Melle, Ingrid; Auestad, Bjørn

    2006-01-01

    Early intervention is assumed to improve outcome in first-episode psychosis, but this has not been proven.......Early intervention is assumed to improve outcome in first-episode psychosis, but this has not been proven....

  20. Genetics Home Reference: early-onset glaucoma

    Science.gov (United States)

    ... Home Health Conditions Early-onset glaucoma Early-onset glaucoma Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Glaucoma is a group of eye disorders in which ...

  1. Living with Disfigurement in Early Medieval Europe

    National Research Council Canada - National Science Library

    Skinner, Patricia

    2017-01-01

    This book examines social and medical responses to the disfigured face in early medieval Europe, arguing that the study of head and facial injuries can offer a new contribution to the history of early...

  2. Perceived Stress and Canadian Early Childcare Educators

    Science.gov (United States)

    Wagner, Shannon L.; Forer, Barry; Cepeda, Ivan L.; Goelman, Hillel; Maggi, Stefania; D'Angiulli, Amedeo; Wessel, Julie; Hertzman, Clyde; Grunau, Ruth E.

    2013-01-01

    Background: Occupational stress for early childcare educators is an area of apparent understudy in the literature. The present study attempted to address this gap and provide some updated data regarding the experiences of this occupational group. Methods: Early childhood workers across a variety of early childhood education settings (N = 69)…

  3. Strategies for Supporting Early Literacy Development

    Science.gov (United States)

    Dennis, Lindsay R.; Horn, Eva

    2011-01-01

    The development of early literacy skills is critical to children's later success in reading and reading-related activities; therefore, understanding how teachers can support early literacy development is equally important. In this article, the authors provide information on how early childhood teachers can use specific strategies and techniques as…

  4. Teen Parents in Early Childhood Interventions

    Science.gov (United States)

    Korfmacher, Jon

    2005-01-01

    This article reviews five large national studies that include significant findings about the effects of early care and intervention on the children of teens. Five large-scale, national early childhood intervention research trials have included teen parents: Early Head Start, Nurse Family Partnership, Parents as Teachers, Healthy Start/Healthy…

  5. Leadership in Early Childhood Special Education

    Science.gov (United States)

    Arora, Samita Berry

    2013-01-01

    With the demands of high quality early childhood special education programs within public school settings, there is a need to place emphasis on research and training regarding early childhood leaders and managers in this complex and diverse field. The focus of this research is to examine what early childhood special education (ECSE) leadership…

  6. Ethics dilemmas of early detection of obesity

    DEFF Research Database (Denmark)

    Vallgårda, Signild

    2016-01-01

    Aim: To discuss the ethics dilemmas of the early detection of overweight and obesity. Methods: Analysis of the ethical aspects of early detection. Results: The early detection of overweight and obesity entails a number of ethical dilemmas because it may both be helpful and harmful. It may help...

  7. Early Learning and Educational Technology Policy Brief

    Science.gov (United States)

    Lee, Joan

    2016-01-01

    Recognizing the growth of technology use in early learning settings, the U.S. Department of Education and U.S. Department of Health and Human Services collaborated in the development of the "Early Learning and Educational Technology Policy Brief" to promote developmentally appropriate use of technology in homes and early learning…

  8. Alcoholism in College: Early Case Finding.

    Science.gov (United States)

    Benforado, Joseph M.

    1982-01-01

    Problem drinking occurs on college campuses. Attempts at early case finding by health professionals may prove valuable as a form of secondary prevention of a potentially serious illness, alcoholism. Early awareness of alcohol-related problems can lead to early referral for diagnosis and treatment. (CJ)

  9. Supporting Mathematical Development in the Early Years

    Science.gov (United States)

    Pound, Linda

    2006-01-01

    This book provides practical guidance for parents, teachers, and other early years workers who want to give children a good start in mathematical development. Showing how competent children are as mathematicians from an early age, the book offers an overview of young children's mathematical behaviour at home and in early years settings. This book…

  10. Ideology and the rise of early states

    NARCIS (Netherlands)

    Meijl, A.H.M. van

    2012-01-01

    Professor Carneiro is a distinguished American scholar who made a seminal contribution to the debate about the rise of the early state. As early as in 1970, he published a landmark paper in the authoritative journal Science on the circumscription theory about the emergence of the (early) state. This

  11. Early infection and prognosis after acute stroke

    DEFF Research Database (Denmark)

    Kammersgaard, L P; Jørgensen, H S; Reith, J

    2001-01-01

    Infection is a frequent complication in the early course of acute stroke and may adversely affect stroke outcome. In the present study, we investigate early infection developing in patients within 3 days of admission to the hospital and its independent relation to recovery and stroke outcome....... In addition, we identify predictors for early infections, infection subtypes, and their relation to initial stroke severity....

  12. Early Childhood Inclusion in the United Kingdom

    Science.gov (United States)

    Blackburn, Carolyn

    2016-01-01

    A policy-to-practice paper is presented of early childhood inclusion in England. The article aims to report the benefits of early intervention services and early childhood inclusion for children with special educational needs and disabilities (SEND), document the chronology of policy development, and discuss research evidence about…

  13. Early Smoking, Education, and Labor Market Performance

    NARCIS (Netherlands)

    Palali, Ali

    2015-01-01

    This study investigates the effects of early smoking on educational attainment and labor market performance. The results show that early smoking adversely affects educational attainment and initial labor market performance, but only for males. The effect of early smoking on initial labor market

  14. The Environment of Early Mars

    Science.gov (United States)

    Matsubara, Yo

    2013-12-01

    A hydrologic routing model was applied to the Noachian cratered highlands to establish the climatic conditions required to maintain lakes and valley networks on early Mars. We used the ratio of precipitation and evaporation (the X-ratio) to express climatic conditions. Simulations were conducted using various X-ratios. The results from the lake analysis showed that many of the lakes that were not identified as overflowing probably overflowed as well. Because overflowing lakes can place constrain on possible climatic condition of early Mars, it is essential to identify as many overflowing craters as possible to understand the environment of early Mars. The multiple regression analyses indicate that incision depth is strongly influenced by gradient and weakly related to discharge. The factors determining incision depend partly on the type of channel bed. However, post-flow modification of the valleys precludes direct determination of bed morphology. We found through both lake and incision depth analysis that climatic conditions on early Mars were at least as moist as those that occurred in the Great Basin region during the Pleistocene (X ≤ 4). We also report on two studies motivated by the occurrence of sinuous paleochannels on Mars. Unconfined meanders require cohesive channel banks, which is obtained commonly by a vegetation cover coupled with high suspended sediment load. The Quinn River, Nevada is a sinuous channel that flows through lacustrine sediments resulting in the river having both bed and banks composed of sediment containing at least 40% mud. In addition, ion chromatography data and SEM images indicate the presence of high solute concentrations. In the absence of vegetation, bank cohesion is provided by mud with salts aiding flocculation and possibly providing additional cohesion through cementation. A 1D depth-averaged linearized meander evolution model was calibrated using the field data collected at the Quinn River. Both approaches gave similar

  15. Excess Early Mortality in Schizophrenia

    DEFF Research Database (Denmark)

    Laursen, Thomas Munk; Nordentoft, Merete; Mortensen, Preben Bo

    2014-01-01

    Schizophrenia is often referred to as one of the most severe mental disorders, primarily because of the very high mortality rates of those with the disorder. This article reviews the literature on excess early mortality in persons with schizophrenia and suggests reasons for the high mortality...... as well as possible ways to reduce it. Persons with schizophrenia have an exceptionally short life expectancy. High mortality is found in all age groups, resulting in a life expectancy of approximately 20 years below that of the general population. Evidence suggests that persons with schizophrenia may...

  16. Early detection of congenital syphilis

    Directory of Open Access Journals (Sweden)

    Nagalakshmi Chowdhary

    2014-01-01

    Full Text Available Late congenital syphilis is a very rare clinical entity, and its early diagnosis and treatment is essential. Dental findings often provide valuable evidence for the diagnosis of late congenital syphilis. It occurs due to the transmission of the disease from an infected mother to her fetus through placenta. This long forgotten disease continues to effect pregnant women resulting in perinatal morbidity and mortality. Congenital syphilis is a preventable disease, and its presence reflects a failure of prenatal care delivery system, as well as syphilis control programs. We are reporting a case of late congenital syphilis with only Hutchinson′s teeth.

  17. Early detection of congenital syphilis.

    Science.gov (United States)

    Chowdhary, Nagalakshmi; Rani, Bs Kavya; Mukunda, K S; Kiran, N K

    2014-01-01

    Late congenital syphilis is a very rare clinical entity, and its early diagnosis and treatment is essential. Dental findings often provide valuable evidence for the diagnosis of late congenital syphilis. It occurs due to the transmission of the disease from an infected mother to her fetus through placenta. This long forgotten disease continues to effect pregnant women resulting in perinatal morbidity and mortality. Congenital syphilis is a preventable disease, and its presence reflects a failure of prenatal care delivery system, as well as syphilis control programs. We are reporting a case of late congenital syphilis with only Hutchinson's teeth.

  18. Selectivity in early prosocial behavior.

    Science.gov (United States)

    Kuhlmeier, Valerie A; Dunfield, Kristen A; O'Neill, Amy C

    2014-01-01

    Prosocial behavior requires expenditure of personal resources for the benefit of others, a fact that creates a "problem" when considering the evolution of prosociality. Models that address this problem have been developed, with emphasis typically placed on reciprocity. One model considers the advantages of being selective in terms of one's allocation of prosocial behavior so as to improve the chance that one will be benefitted in return. In this review paper, we first summarize this "partner choice" model and then focus on prosocial development in the preschool years, where we make the case for selective partner choice in early instances of human prosocial behavior.

  19. Early prosocial development across cultures.

    Science.gov (United States)

    Callaghan, Tara; Corbit, John

    2017-08-17

    Human prosociality is ubiquitous, even though it may be manifested differently across cultures. Low cost helping and sharing emerge early in development, and at similar levels, across cultures having vastly different sociocultural niches. Developmental trajectories for costly sharing diverge across cultures around middle childhood, in line with differences in the sociocultural niches that children experience. Cultural developmental research has focussed primarily on the emergence and development of prosocial behaviour, and would benefit from an examination of the interplay between psychological (cognitive, motivational) and sociocultural (norms, developmental niche) foundations over ontogeny. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Selectivity in Early Prosocial Behavior

    Directory of Open Access Journals (Sweden)

    Valerie eKuhlmeier

    2014-07-01

    Full Text Available Prosocial behavior requires expenditure of personal resources for the benefit of others, a fact that creates a ‘problem’ when considering the evolution of prosociality. Models that address this problem have been developed, with emphasis typically placed on reciprocity. One model considers the advantages of being selective in terms of one’s allocation of prosocial behavior so as to improve the chance that one will be benefitted in return. In this review paper, we first summarize this partner choice model and then focus on prosocial development in the preschool years, where we make the case for selective partner choice in early instances of human prosocial behavior.