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Sample records for vice chair sam

  1. Career development resource: educational leadership in a department of surgery: vice chairs for education.

    Science.gov (United States)

    Sanfey, Hilary; Boehler, Margaret; DaRosa, Debra; Dunnington, Gary L

    2012-07-01

    The growing appreciation of the need to adopt an evidence-based approach to teaching and assessment has led to a demand for faculty who are well versed in best practices in education. Surgeons with interest and expertise in instruction, curriculum development, educational research, and evaluation can have an important impact on the educational mission of a department of surgery. The increased fervor for accountability in education together with the challenges imposed by accreditation agencies and hospitals has made educational leadership responsibilities more time consuming and complex. In response to this, an increasing number of department chairs created Vice Chair for Education positions to support clerkship and program directors and ensure the department's education mission statement is fulfilled. Copyright © 2012 Elsevier Inc. All rights reserved.

  2. 6 March 2013 - Committee for Employment and Learning, Northern Ireland Legislative Assembly, United Kingdom of Great Britain and Northern Ireland in the LHC tunnel and visiting the LHCb experiment at LHC Point 8. Director for Accelerators and Technology S. Myers with Vice-Chair T. Buchanan.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    6 March 2013 - Committee for Employment and Learning, Northern Ireland Legislative Assembly, United Kingdom of Great Britain and Northern Ireland in the LHC tunnel and visiting the LHCb experiment at LHC Point 8. Director for Accelerators and Technology S. Myers with Vice-Chair T. Buchanan.

  3. 16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

  4. Leadership Considerations for Executive Vice Chairs, New Chairs, and Chairs in the 21st Century

    Science.gov (United States)

    Kunkel, Elisabeth J. S.; Lehrmann, Jon A.; Vergare, Michael J.; Roberts, Laura Weiss

    2013-01-01

    The need to fulfill academic goals in the context of significant economic challenges, new regulatory requirements, and ever-changing expectations for leadership requires continuous adaptation. This paper serves as an educational resource for emerging leaders from the literature, national leaders, and other "best practices" in the…

  5. James Lyon. Miami Vice.

    Directory of Open Access Journals (Sweden)

    Chrysavgi Papayianni

    2011-04-01

    Full Text Available Despite the shortness of its length, Miami Vice by James Lyons is a meticulous study of NBC’s series of the same title, attempting to provide an overview of the show’s social, socio-cultural, and industrial-economic circumstances surrounding its production and distribution in order to highlight its status as a “defining show of its era” (3. The series starring Don Johnson as James Crocket and Philip Michael Thomas as Ricardo Tubbs appeared in 1984. As a continuation of the cop shows of the p...

  6. SAM in a Nutshell.

    Science.gov (United States)

    Givens, Larry R.

    2000-01-01

    Explains what the Association of Higher Education Facilities Officers' Strategic Assessment Model (SAM) is and how to use it to achieve organizational excellence through continuous improvement. Showing features of both the Malcolm Baldrige programs and the Balanced Scorecard, the SAM components are described along with an explanation of the four…

  7. SAM EMP (SEMP) model

    Energy Technology Data Exchange (ETDEWEB)

    Thatcher, R.M.

    1984-05-01

    The Surface-To-Air Missile (SAM) Electro-Magnetic-Pulse (EMP) (SEMP) model simulates the illumination of an entire SAM brigade with an EMP weapon. It computes probability distributions of SAM brigade performance levels after an EMP attack has occurred. Brigade performance is determined by the combination of components that survive the EMP. Accordingly, the SEMP model is separated into the component failure model and the condition model. The component failure model computes the failure probability of each component in the brigade from data supplied by two input data files. The condition model converts component failure probabilities into brigade performance in the form of missile availability probability tables.

  8. SAM Photovoltaic Model Technical Reference

    Energy Technology Data Exchange (ETDEWEB)

    Gilman, P. [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-05-27

    This manual describes the photovoltaic performance model in the System Advisor Model (SAM). The U.S. Department of Energy’s National Renewable Energy Laboratory maintains and distributes SAM, which is available as a free download from https://sam.nrel.gov. These descriptions are based on SAM 2015.1.30 (SSC 41).

  9. Congressmember Sam Farr

    OpenAIRE

    Farmer, Ellen

    2010-01-01

    United States Congressmember Sam Farr, one of the political heroes of the sustainable agriculture movement, was interviewed by Ellen Farmer on August 23, 2007. A fifth-generation Californian, Farr was born in 1941. He is the son of California State Senator Fred Farr, who sponsored a law requiring toilets in the fields for farm workers, as well as other landmark environmental legislation. Sam Farr began his career in public service in 1964, in the Peace Corps in Colombia. Before his e...

  10. Vice Presidents' Foreword

    Science.gov (United States)

    is dependent not only on attracting high quality papers, but on the preservation of high standards in the overall editorial process. This requires, inter alia, a sympathetic managing editor to assist non-native English speakers in Europe and beyond to communicate their research findings with good clarity. We are highly fortunate that Dr j S G (Jim) McCulloch, who has had such a major impact on the success of the Journal of Hydrology, has agreed to take on the onerous task of launching and managing HESS. He will be supported by a panel of Scientific Editors and by an Editorial Board, who will advise him. We are indebted to Dr McCulloch and his editorial office team for their dedicated efforts in bringing this first issue to fruition. We also thank the authors, who have entrusted their papers to HESS, the reviewers who have responded so promptly and Arne Richter, the Secretary-General of EGS, for his continual support and enthusiasm for this venture. Finally, and most important of all, we appeal to you, and all members of the scientific community, to support HESS by * taking out a personal subscription; * arranging for an institutional subscription; * contributing your best papers; * helping with the peer review process. By rallying around HESS and giving it the priority which will ensure that high quality is achieved from the outset, we can, as a community, eventually match the achievements of WRR. You and future generations of European hydrologists will be the beneficiaries. Philip O'Kane Enda O'Connell EGS Vice-President Past-EGS Vice-President (Hydrological Sciences) (Hydrological Sciences)

  11. Vice Presidents' Foreword

    Directory of Open Access Journals (Sweden)

    1997-01-01

    of a new journal is dependent not only on attracting high quality papers, but on the preservation of high standards in the overall editorial process. This requires, inter alia, a sympathetic managing editor to assist non-native English speakers in Europe and beyond to communicate their research findings with good clarity. We are highly fortunate that Dr j S G (Jim McCulloch, who has had such a major impact on the success of the Journal of Hydrology, has agreed to take on the onerous task of launching and managing HESS. He will be supported by a panel of Scientific Editors and by an Editorial Board, who will advise him. We are indebted to Dr McCulloch and his editorial office team for their dedicated efforts in bringing this first issue to fruition. We also thank the authors, who have entrusted their papers to HESS, the reviewers who have responded so promptly and Arne Richter, the Secretary-General of  EGS, for his continual support and enthusiasm for this venture. Finally, and most important of all, we appeal to you, and all members of the scientific community, to support HESS by * taking out a personal subscription; * arranging for an institutional subscription; * contributing your best papers; * helping with the peer review process. By rallying around HESS and giving it the priority which will ensure that high quality is achieved from the outset, we can, as a community, eventually match the achievements of WRR. You and future generations of European hydrologists will be the beneficiaries. Philip O'Kane                                                                  Enda O'Connell EGS Vice-President                                                       Past-EGS Vice-President (Hydrological Sciences                                                (Hydrological Sciences

  12. SAM Theory Manual

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Rui [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-03-01

    The System Analysis Module (SAM) is an advanced and modern system analysis tool being developed at Argonne National Laboratory under the U.S. DOE Office of Nuclear Energy’s Nuclear Energy Advanced Modeling and Simulation (NEAMS) program. SAM development aims for advances in physical modeling, numerical methods, and software engineering to enhance its user experience and usability for reactor transient analyses. To facilitate the code development, SAM utilizes an object-oriented application framework (MOOSE), and its underlying meshing and finite-element library (libMesh) and linear and non-linear solvers (PETSc), to leverage modern advanced software environments and numerical methods. SAM focuses on modeling advanced reactor concepts such as SFRs (sodium fast reactors), LFRs (lead-cooled fast reactors), and FHRs (fluoride-salt-cooled high temperature reactors) or MSRs (molten salt reactors). These advanced concepts are distinguished from light-water reactors in their use of single-phase, low-pressure, high-temperature, and low Prandtl number (sodium and lead) coolants. As a new code development, the initial effort has been focused on modeling and simulation capabilities of heat transfer and single-phase fluid dynamics responses in Sodium-cooled Fast Reactor (SFR) systems. The system-level simulation capabilities of fluid flow and heat transfer in general engineering systems and typical SFRs have been verified and validated. This document provides the theoretical and technical basis of the code to help users understand the underlying physical models (such as governing equations, closure models, and component models), system modeling approaches, numerical discretization and solution methods, and the overall capabilities in SAM. As the code is still under ongoing development, this SAM Theory Manual will be updated periodically to keep it consistent with the state of the development.

  13. Sam and Wahua (24)

    African Journals Online (AJOL)

    DELL

    2017-10-27

    Oct 27, 2017 ... This study investigated the anatomical features, nutraceutical potentials and heavy metal compositions in two varieties of .... variety (Plates 1-6). Sam and Wahua: Comparative Anatomy, Nutraceutical Potentials and Heavy Metal Composition .... High content of tannin decreases protein quality by decreasing ...

  14. CareSam

    DEFF Research Database (Denmark)

    Liveng, Anne; Christensen, Jonas

    2016-01-01

    This article presents findings and discussions generated on the basis of the Danish-Swedish development project CareSam. The article will on the one hand focus on how work in groups consisting of representatives from different levels in the elderly care sector at one time served as learning spaces...... and cultural encounters in which established notions of older people and elderly care were challenged and discussed. Inspired by action research these challenges were brought forth through discussions of and through insight in practical experiences. On the other hand it will focus on the tendencies to narrow...... in the project-groups this paper will ask whether it is possible to represent care work for elderly people with all the ambiguities it holds: How can we as researchers represent both meaningfulness and straining dimensions of care work? Can we avoid either supporting Florence Nightingale-ideals or cementing...

  15. Message from Vice-Chancellor

    Science.gov (United States)

    Nasir Ibrahim, Daing

    2013-12-01

    Salam Malaysia! First and foremost, I want to thank all 2nd International Conference on Mechanical Engineering Research (ICMER 2013) organisers for inviting me to address and officiate this conference. This 2nd ICMER 2013 provides a platform to bring together not only researchers, postgraduate students but also industrial people. With this platform, ICMER will embark on a whole process of making new discoveries and then translating them into products and services for the marketplace and this is only made possible with people like all of you. I would like to congratulate the ICMER 2013 organisers for the achievement of collecting 208 papers for this conference. Submissions received from 17 local universities, 7 industrial companies and 9 different countries is a great achievement for UMP. I am very happy to welcome all of you from Malaysia, Iran, Turkey, Japan, India, Australia, Ireland, Saudi Arabia and Bangladesh to this conference. As one of Malaysia's Public Universities, UMP's main challenge is to remain competitive and relevant by offering high quality technical academic programmes and research activities, focusing on its niche areas. New knowledge and findings cannot be generated without any research and development (R&D) activities. These efforts will undoubtedly generate lots of interesting results and new knowledge either bring further commercialisation activities. The Malaysian government has invested a huge sum of Ringgits in R&D over the years. Therefore, UMP must produce more quality researchers and graduates to ensure Malaysia reaps the returns from these investments vice versa of progressive economic growth for the country. UMP's 2011-2015 Strategic Plan determines to strengthen and sustained its financial support by allocating research grants and industry collaboration and consultations through its business and commercial unit. On behalf of UMP, I would like to express my appreciation to all committee members of ICMER 2013 from Faculty of Mechanical

  16. System for Award Management (SAM) API

    Data.gov (United States)

    General Services Administration — The SAM API is a RESTful method of retrieving public information about the businesses, organizations, or individuals (referred to as entities) within the SAM entity...

  17. Uncle Sam vs. John Bull.

    Science.gov (United States)

    Mellini, Peter

    1990-01-01

    Compares John Bull and Uncle Sam as iconographic symbols, respectively personifying male images of the British and United States national characters. Recounts their origins, evolutions, and representative values, and includes cartoons depicting the evolution. Describes female counterparts: Britannia and Columbia/Liberty. (CH)

  18. 21 CFR 890.3100 - Mechanical chair.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food... DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair. (a) Identification. A mechanical chair is a manually operated device intended for medical purposes that is used to...

  19. Robotic chair at steep and narrow stairways

    Science.gov (United States)

    Imazato, Masahiro; Yamaguchi, Masahiro; Moromugi, Shunji; Ishimatsu, Takakazu

    2007-12-01

    A robotic chair is developed to support mobility of elderly and disabled people living in the house where steep and narrow stairways are installed. In order to deal with such mobility problem the developed robotic chair has a compact original configuration. The robotic chair vertically moves by actuation of electric cylinders and horizontally moves by push-pull operation given by a care-giver. In order to navigate safely every action of the chair is checked by the operator. Up-and-down motions of the robotic chair on the stairway are executed through combinations of motor and cylinder actuations. Performance of the robotic chair was evaluated through two kinds of experiments. The excellent ability of the robotic chair could be confirmed through these experiments.

  20. Leading Learning: Science Departments and the Chair

    Science.gov (United States)

    Melville, Wayne; Campbell, Todd; Jones, Doug

    2016-01-01

    In this article, we have considered the role of the chair in leading the learning necessary for a department to become effective in the teaching and learning of science from a reformed perspective. We conceptualize the phrase "leading learning" to mean the chair's constitution of influence, power, and authority to intentionally impact…

  1. Axiology, the Subject and the Chair

    Science.gov (United States)

    Melville, Wayne; Campbell, Todd; Jones, Doug

    2017-08-01

    This article addresses two gaps in the literature related to science department chairs: the axiological relationship between the chair and science, the subject, and the perceptions of the chair with respect to teaching and learning within their departments. In this work, axiology is used to understand how the chair's values toward the subject influenced his own perceived capacity to lead learning within his department in a reformed discourse. A narrative inquiry methodology was used to consider the chair's experiences in the development of his identify over his life span in the form of two stories: (1) the relationship between the chair and science, the subject, and (2) the perceptions of the chair with regards to teacher learning within the department. The findings revealed that the work and career of the chair in this study were authored by strong elements of personal continuity and points of stability around the valuing of science, the subject, even as this valuing evolved from being more focused on epistemic values early in his career, to being more concerned with universal values connected to his legacy and his department later in his career.

  2. Performance Simulation of Solid Wood Chairs

    Directory of Open Access Journals (Sweden)

    Silviu NEMEŞ

    2014-03-01

    Full Text Available Chairs made of solid wood belong to a category which requires special attention due to its frequent structural stressing. This study proposes the identification through load simulation of those structural elements, which can potentially become vulnerable. In this way measures can be taken during the design process to avoid eventual drawbacks and appropriate solutions can be found. The chair types that were the subject of this analysis have a simple construction, being commonly used in various human activities, but also the sitting ergonomics were kept in mind. When determining their dimensions, standards, studies and existing research were followed. The chair types were chosen as follows: a chair without stretchers, one with lateral stretchers and a lounge chair. The wood species for which the study was made is Fraxinus excelsior – ash wood, which shows average mechanical performance when compared to other hardwoods preferred by chair manufacturers. Its properties were used for a further analysis. Identifying the areas of the chair structure which are stressed by the human body was necessary in order to simulate real-life conditions. The finite element method was used, with a dedicated software. The interpretation of results is able to prove the quality of the design process. The proposed methodology may be applicable also for more complex chair structures.

  3. Samsø Energy Vision 2030

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Hansen, Kenneth; Ridjan, Iva

    The purpose of this report is to investigate potential scenarios for converting Samsø into 100% renewable energy supply in 2030 with focus on local electricity and biomass resources. Firstly, a 2013 reference scenario is established to investigate whether Samsø is 100% renewable today. Next, scen...

  4. CERN welcomes the Spanish Vice-President

    CERN Multimedia

    Anaïs Schaeffer

    2015-01-01

    On 29 September, CERN had the pleasure of welcoming the Vice-President of the Government of Spain, Soraya Sáenz de Santamaría, for a visit of the Laboratory.   From left to right: Lluis Miralles (Head of the General Infrastructure Services department), Soraya Sáenz de Santamaría (Vice-President of the Government of Spain) and José Miguel Jiménez (Head of the Technology department).   The Vice-President was accompanied by Carmen Vela, Spanish Secretary of State for Research, Development and Innovation, Bernardo de Sicart Escoda, Ambassador of Spain to Switzerland, and Ana Menéndez Pérez, Permanent Representative of Spain to the United Nations and International Organizations in Geneva. Their tour started at LHC Point 1, where CERN Director-General Rolf Heuer welcomed them and gave them an introduction to CERN's activities. Jos&ea...

  5. Report of ad hoc meeting of the Chairs, Vice-Chairs and Central Crop Database Managers of the ECPGR Solanaceae and Cucurbits Working Groups

    NARCIS (Netherlands)

    Díez Niclós, M.J.; Valcárcel, J.V.; Íñigo, A.G.; Dooijeweert, van W.; Menting, F.; Weerden, van der G.; Daunay, M.

    2013-01-01

    The scope of this two-day ad hoc meeting was to explore the possibility to abandon Central Crop Databases (CCDBs) and focus on EURISCO, in order to avoid duplication of data and working efforts. The main facilities of both systems were discussed. Current progress concerning the selection of Most

  6. Chair Talk: Resources to Maximize Administrative Efforts

    Science.gov (United States)

    MacDonald, H.; Chan, M. A.; Bierly, E. W.; Manduca, C. A.; Ormand, C. J.

    2009-12-01

    Earth science department chairs are generally scientists who have little/no formal administrative training. The common rotation of faculty members in three-six year cycles distributes the heavy leadership responsibilities but involves little preparation beforehand to deal with budgets, fundraising, personnel issues, confrontations, and crises. The amount of information exchange and support upon exit and handoff to the next chair is variable. Resources for chairs include workshops, meetings (ranging from annual meetings of geoscience chairs to monthly meetings of small groups of chairs from various disciplines on a campus), discussions, and online resources. These resources, some of which we designed in the past several years, provide information and support for chairs, help them share best practices, and reduce time spent “reinventing the wheel”. Most of these resources involve groups of chairs in our discipline who meet together. The AGU Board of Heads and Chairs of Earth and Space Science Departments offers annual one-day workshops at the Fall AGU meeting. The specific topics vary from year to year; they have included goals and roles of heads and chairs, fundraising and Advisory Boards, student recruitment, interdisciplinarity, dual-career couples, and undergraduate research. The workshop provides ample opportunities for open discussion. Annual one-two day meetings of groups of geoscience department chairs (e.g., research universities in a particular region) provide an opportunity for chairs to share specific data about their departments (e.g., salaries, graduate student stipends, information about facilities) and discuss strategies. At the College of William and Mary, a small group of chairs meets monthly throughout the year; each session includes time for open discussion as well as a more structured discussion on a particular topic (e.g., merit review, development and fundraising, mentoring early career faculty and the tenure process, leadership styles

  7. Quality Control Guidelines for SAM Chemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the chemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  8. Quality Control Guidelines for SAM Biotoxin Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the pathogen methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  9. Quality Control Guidelines for SAM Pathogen Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the biotoxin methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  10. Quality Control Guidelines for SAM Radiochemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the radiochemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  11. Pediatric dental chair vs. traditional dental chair: A pediatric dentist′s poll

    Directory of Open Access Journals (Sweden)

    Khushboo Barjatya

    2015-01-01

    Full Text Available Objective: Proper positioning of the child patient, can not only have positive ramifications for the operator′s posture, comfort, and career longevity - it can also lead to better treatment and increased productivity. The aim of the survey questionnaire was to assess the utilization, need, and attitude concerning dental chairs among pediatric dentist while working on and managing the child patient. Study Design: The questions were structured using adobe forms central online software, regarding the user-friendliness of pediatric dental chair vs. traditional adult dental chair available in the market. Results: Our result shows that out of 337 respondents, 79% worked on pediatric dental chair, whereas 21% had no experience of it. Of these 79% pediatric dentist, 48% preferred pediatric dental chair. But pediatric dental problem still has certain disadvantages like higher cost, leg space problem, lower availability, etc. Conclusion: During the research it was found that ergonomics and usability issues were the main problems. Thus, pediatric dental chair is not so popular in the current scenario. This study allowed for general ideas for the improvement of dental chairs and thus improved dental chair would fill the gap in the current scenario.

  12. Great auricular neuropraxia with beach chair position.

    Science.gov (United States)

    Joshi, Minal; Cheng, Ruth; Kamath, Hattiyangadi; Yarmush, Joel

    2017-01-01

    Shoulder arthroscopy has been shown to be the procedure of choice for many diagnostic and therapeutic interventions. Neuropraxia of the great auricular nerve (GAN) is an uncommon complication of shoulder surgery, with the patient in the beach chair position. We report a case of great auricular neuropraxia associated with direct compression by a horseshoe headrest, used in routine positioning for uncomplicated shoulder surgery. In this case, an arthroscopic approach was taken, under regional anesthesia with sedation in the beach chair position. The GAN, a superficial branch of the cervical plexus, is vulnerable to neuropraxia due to its superficial anatomical location. We recommend that for the procedures of the beach chair position, the auricle be protected and covered with cotton and gauze to avoid direct compression and the position of the head and neck be checked and corrected frequently.

  13. Validation of SAM 2 and SAGE satellite

    Science.gov (United States)

    Kent, G. S.; Wang, P.-H.; Farrukh, U. O.; Yue, G. K.

    1987-01-01

    Presented are the results of a validation study of data obtained by the Stratospheric Aerosol and Gas Experiment I (SAGE I) and Stratospheric Aerosol Measurement II (SAM II) satellite experiments. The study includes the entire SAGE I data set (February 1979 - November 1981) and the first four and one-half years of SAM II data (October 1978 - February 1983). These data sets have been validated by their use in the analysis of dynamical, physical and chemical processes in the stratosphere. They have been compared with other existing data sets and the SAGE I and SAM II data sets intercompared where possible. The study has shown the data to be of great value in the study of the climatological behavior of stratospheric aerosols and ozone. Several scientific publications and user-oriented data summaries have appeared as a result of the work carried out under this contract.

  14. ADE 2000 Survey of Department Chair Compensation.

    Science.gov (United States)

    ADE Bulletin, 2002

    2002-01-01

    Surveys the types of support and compensation that chairs in the Association of Departments of English (ADE) community receive. Notes that in the survey larger institutions and those granting advanced degrees are overrepresented, as they are in the ADE membership. Presents results of the surveys in 17 different tables. (SG)

  15. Perceptions of Leadership Styles of Department Chairs

    Science.gov (United States)

    Whitsett, Glee

    2007-01-01

    Much has been written about leadership in business management, but very little research has been done on leadership in academic departments. Department chairs have the authority to make most departmental decisions, but rarely does formal training exist for this position. Therefore, there is a need to study how the leadership styles among…

  16. ECOHEALTH CHAIRS in HEALTH and GLOBAL ENVIRONMENTAL ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Francine Sinzinkayo

    ECOHEALTH CHAIRS in HEALTH and GLOBAL ENVIRONMENTAL CHANGE in SUB-SAHARAN AFRICA. Frequently asked questions. 1. Can Applicants from the listed eligible countries in Africa partner with institutions not based in Africa? Applicants from Sub-Saharan Africa can partner with institutions based outside ...

  17. International Research Chairs Initiative | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The International Research Chairs Initiative (IRCI) is a seven-year, CA$8 million research program that pairs top research talent from universities in Canada with their counterparts in developing countries to address key development challenges. These specialists share their advanced skills and knowledge to confront issues ...

  18. Repositioning chairs in benign paroxysmal positional vertigo

    DEFF Research Database (Denmark)

    West, Niels; Hansen, Søren; Møller, Martin Nue

    2016-01-01

    The objective was to evaluate the clinical value of repositioning chairs in management of refractory benign paroxysmal positional vertigo (BPPV) and to study how different BPPV subtypes respond to treatment. We performed a retrospective chart review of 150 consecutive cases with refractory vertigo...

  19. Spondyloarthropathies in Autoimmune Diseases and Vice Versa

    Science.gov (United States)

    Pérez-Fernández, Oscar M.; Mantilla, Rubén D.; Cruz-Tapias, Paola; Rodriguez-Rodriguez, Alberto; Rojas-Villarraga, Adriana; Anaya, Juan-Manuel

    2012-01-01

    Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs (N = 148). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs (N = 1077) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren's syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6%). There were two patients presenting with SS in the SpA group (1.4%) and 5 patients with autoimmune thyroiditis (3.5%). The global prevalence of ADs in SpAs was 4.86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs. PMID:22400103

  20. PERANANTAN SAM CAI KONGDALAM SEJARAH CIREBON THE ROLE OF TAN SAM CAI KONGIN CIREBON HISTORY

    Directory of Open Access Journals (Sweden)

    Rusyanti Rusyanti

    2016-06-01

    ABSTRAK Keberadaan makam dan inskripsi padanisan kuno sebagai bukti arkeologis memiliki informasi yang penting dan berhubungan dengan banyak hal. Tulisan ini bertujuan melacak tokoh dan peran seorang China yang bernamaTan Sam Cai Kongyang makamnya berada di Sukalila, Cirebon. Melalui analisis arkeologi dan sejarah diketahui bahwa Tan Sam Cai Kongmerupakan tokoh sejarah yang hidup pada sekitar abad ke-17M. Gelar sebagai Tumenggung Aria Wira Cula yang tertulis pada prasasti menandakan perananya sebagai orang penting dan dekat dengan lingkungan keraton.   Kata Kunci: Cirebon, Tan Sam CaiKong, China.

  1. Samâ’ dalam Tradisi Tasawuf

    Directory of Open Access Journals (Sweden)

    Said Aqil Siradj

    2014-01-01

    Full Text Available Samâ‘ in Tasawuf has been a very important element in the dissemination of this spiritual dimension of Islam. Yet, it has received very little both from the practitioners of Tasawuf and its intellectuals. This paper tries to expose this simply in a hope to make it heard in the academic and popular circle. Here, samâ‘ is not only understood as a form of music, as many would do, but also as an art of listening of which music is certainly part. The paper will explore the meaning and definition of this term, putting emphasis on its many-faceted function in the formation and development of one’s soul and spirituality. It is argued that soul is musical and artistic. Using art and music to talk to soul is therefore the proper way and means. The paper will also try to show that samâ‘ is also an indispensable part of spiritual method to reach and know God. Knowledge of God in other words, can be gained through this practice. Hence, samâ‘ is treated not only as a form of entertainment, but also a kind of practical epistemology.

  2. Essay: Physical Review Letters; Sam Goudsmit's Vision.

    Science.gov (United States)

    Adair, Robert K

    2008-01-18

    Sam Goudsmit implemented his vision of converting the Letters section of Physical Review into a distinct journal fifty years ago. Physical Review Letters was designed to publish "only papers that really deserve rapid communication." The new journal became so successful with physicists throughout the world that Physical Review Letters now publishes 3500 Letters per year.

  3. The Vices of Economists; The Virtues of the Bourgeoisie

    NARCIS (Netherlands)

    McCloskey, Deirdre N.

    1997-01-01

    The 'vices' are three bad habits into which economists have fallen over the past fifty years: bad statistics, bad theory, and bad applications of statistics and theory to public affairs. This book details the vices, tracing them to the influence of three giants of the 1940s and 1950s in economics,

  4. Executive Assistant to the Vice-President, Corporate Strategy and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary Under the direction of the Vice-President, Corporate Strategy and Communications, and reporting to the Senior Corporate Strategy and Communications Advisor, the Executive Assistant provides secretarial and administrative support to the OVP-CSC, and in particular to the Vice-President; performing a ...

  5. 11 CFR 103.4 - Vice Presidential candidate campaign depositories.

    Science.gov (United States)

    2010-01-01

    ... designated by the principal campaign committee of a political party's candidate for President shall be the campaign depository for that political party's candidate for the office of Vice President. ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Vice Presidential candidate campaign...

  6. 22 CFR 40.24 - Prostitution and commercialized vice.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Prostitution and commercialized vice. 40.24... Certain Crimes § 40.24 Prostitution and commercialized vice. (a) Activities within 10 years preceding visa... United States solely, principally, or incidentally to engage in prostitution, or has engaged in...

  7. 29 CFR 1601.4 - Vice Chairman's functions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Vice Chairman's functions. 1601.4 Section 1601.4 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURAL REGULATIONS Definitions § 1601.4 Vice Chairman's functions. The member of the Commission designated by the President to...

  8. Obituary: Sam Roweis (1972-2010)

    Science.gov (United States)

    Hogg, David

    2011-12-01

    Computer scientist and statistical astronomer Sam Roweis took his own life in New York City on 2010 January 12. He was a brilliant and accomplished researcher in the field of machine learning, and a strong advocate for the use of computational statistics for automating discovery and scientific data analysis. He made several important contributions to astronomy and was working on adaptive astronomical data analysis at the time of his death. Roweis obtained his PhD in 1999 from the California Institute of Technology, where he worked on a remarkable range of subjects, including DNA computing, modeling of dynamical systems, signal processing, and speech recognition. During this time he unified and clarified some of the most important data analysis techniques, including Principal Component Analysis, Hidden Markov Models, and Expectation Maximization. His work was aimed at making data analysis and modeling faster, but also better justified scientifically. The last years of his PhD were spent in Princeton NJ, where he came in contact with a young generation of cosmologists thinking about microwave background and large-scale structure data. In a postdoc at University College London, Roweis co-created the Locally Linear Embedding (LLE) algorithm; a simple but flexible technique for mapping a large data set onto a low-dimensional manifold. The LLE paper obtained more than 2700 citations in 9 years, launched a new sub-field of machine learning known as "manifold learning," and inspired work in data visualization, search, and applied mathematics. In 2001, Roweis took a faculty job at the University of Toronto Computer Science Department. He continued working on data analysis methods that have probabilistic interpretation and therefore scientific applicability, but at the same time have good performance on large data sets. He was awarded a Sloan Fellowship, a Canada Research Chair, and a fellowship of the Canadian Institute for Advanced Research, among other honors and awards

  9. 21 CFR 880.6140 - Medical chair and table.

    Science.gov (United States)

    2010-04-01

    ...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6140 Medical chair and table. (a) Identification. A medical chair or table is a device... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical chair and table. 880.6140 Section 880.6140...

  10. Raman Chair | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Raman Chair. The Raman Chair was instituted in 1972 by the Government of India to commemorate the memory of the founder of the Academy, Sir C. V. Raman. Eminent scientists are invited by the Council of the Academy to occupy the Chair, for periods of between six weeks and six months. Raman Professors who have ...

  11. New South Africa–Canada Research Chairs Initiative | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-12-08

    Dec 8, 2016 ... They build on NRF's existing South African Research Chairs Initiative (SARChI), as well as on the Industrial Research Chairs program, funded in part by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canada Research Chairs Program (CRCP). Funded jointly by ...

  12. Samuel P. Massie Chair of Excellence Program

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, James H. [Howard Univ., Washington, DC (United States)

    2014-12-01

    Abstract In 1994 the Department of Energy established the DOE Chair of Excellence Professorship in Environmental Disciplines Program. In 2004, the Massie Chair of Excellence Professor at Howard University transitioned from Dr. Edward Martin to Dr. James H. Johnson, Jr. At the time of his appointment Dr. Johnson served as professor of civil engineering and Dean of the College of Engineering, Architecture and Computer Sciences. Program activities under Dr. Johnson were in the following areas: • Increase the institution’s capacity to conduct scientific research and technical investigations at the cutting-edge. • Promote interactions, collaborations and partnerships between the private sector, Federal agencies, majority research institutes and other HBCUs. • Assist other HBCUs in reaching parity in engineering and related fields. • Mentor young investigators and be a role model for students.

  13. Great auricular neuropraxia with beach chair position

    OpenAIRE

    Joshi M; Cheng R; Kamath H; Yarmush J

    2017-01-01

    Minal Joshi,1 Ruth Cheng,2 Hattiyangadi Kamath,1 Joel Yarmush1 1Department of Anesthesiology, New York Methodist Hospital, New York, NY, USA; 2School of Medicine, St. George’s University, Grenada, West Indies Abstract: Shoulder arthroscopy has been shown to be the procedure of choice for many diagnostic and therapeutic interventions. Neuropraxia of the great auricular nerve (GAN) is an uncommon complication of shoulder surgery, with the patient in the beach chair position. We report...

  14. New product development: A batik multifunctional chair

    Science.gov (United States)

    Indrawati, Sri; Sukmaningsih, Nias

    2017-11-01

    The biggest challenge facing by Batik industry in ASEAN Economic Community (AEC) era is the greater number of fashion competitors both domestically and internationally. Based on that condition, the development of new product variants by considering product performance and price is needed. This research was conducted to develop batik products with a new target market. Products that being developed is batik multifunctional chair using integrated value engineering and analytic hierarchy process methods. This research has been done in several stages, ie. Information stage, creative stage, value analysis and product prototyping. The results of this research shows that the batik multifunctional chair product criteria are aesthetic (29%), multifunctional (34%) and ergonomic (37%). There are three new product design alternatives that successfully being developed. Based on value analysis, the product design alternatives that have the highest value is alternative design 2, the value is 2,37. The production cost for this design is Rp. 500.000,-. Alternative design 2 specification are using Mahoni wood, Batik parang rusak pattern with natural coloring process, can be used as table and fit with customer's body anthropometry. Then a batik multifunctional chair prototype is developed based on the best alternative design.

  15. Great auricular neuropraxia with beach chair position

    Directory of Open Access Journals (Sweden)

    Joshi M

    2017-07-01

    Full Text Available Minal Joshi,1 Ruth Cheng,2 Hattiyangadi Kamath,1 Joel Yarmush1 1Department of Anesthesiology, New York Methodist Hospital, New York, NY, USA; 2School of Medicine, St. George’s University, Grenada, West Indies Abstract: Shoulder arthroscopy has been shown to be the procedure of choice for many diagnostic and therapeutic interventions. Neuropraxia of the great auricular nerve (GAN is an uncommon complication of shoulder surgery, with the patient in the beach chair position. We report a case of great auricular neuropraxia associated with direct compression by a horseshoe headrest, used in routine positioning for uncomplicated shoulder surgery. In this case, an arthroscopic approach was taken, under regional anesthesia with sedation in the beach chair position. The GAN, a superficial branch of the cervical plexus, is vulnerable to neuropraxia due to its superficial anatomical location. We recommend that for the procedures of the beach chair position, the auricle be protected and covered with cotton and gauze to avoid direct compression and the position of the head and neck be checked and corrected frequently. Keywords: neuropraxia, anesthesia, arthroscopy, great auricular nerve

  16. Australian Higher Education Leaders in Times of Change: The Role of Pro Vice-Chancellor and Deputy Vice-Chancellor

    Science.gov (United States)

    Scott, Geoff; Bell, Sharon; Coates, Hamish; Grebennikov, Leonid

    2010-01-01

    This paper discusses responses provided by 31 Pro Vice-Chancellors (PVCs) and Deputy Vice-Chancellors (DVCs) who were part of a larger study of more than 500 higher education leaders in roles ranging from DVC to head of programme in 20 Australian universities. Using both quantitative and qualitative data the paper gives an insider's perspective on…

  17. Metal/SAM/metal junctions studied from first principles

    Energy Technology Data Exchange (ETDEWEB)

    Kucera, Jan; Gross, Axel [Institute for Theoretical Chemistry, Ulm University, D-89069 Ulm (Germany)

    2010-07-01

    There is currently a strong interest in sandwich structures made of self-assembled monolayers (SAMs) between two metal layers (M/SAM/M) because of their potential in future nanoelectronics. Recently, a M/SAM/M/SAM/M ''double decker'' junction was realized with two 4-mercaptopyridine SAMs sandwiched between an Au electrode and Pd and Pt monolayers. We have performed periodic electronic structure calculations based on density function theory (DFT) to describe various phenomena playing a role in hybrid systems such as Au/SAM, Au/SAM/Pd, and Au/SAM/Pd/SAM/Pt with the SAMs consisting of the bifunctional thioaromatics 4-aminothiophenol or 4-mercaptopyridine. Based on the calculated local density of states (LDOS) of the metal layers, possible explanations for experimental results will be provided which show a reduced DOS at the Fermi energy. In addition, the role of van der Waals forces on the structure and stability of the SAMs has been addressed by performing DFT calculations with semi-empirical corrections for dispersion effects.

  18. The Jepara Chairs Based on Their Style and Period

    Directory of Open Access Journals (Sweden)

    Octaviana S.C. Rombe

    2016-04-01

    Full Text Available The purpose of this article was to identify the Jepara chairs based on its style and period. Qualitative research such as doing interviews with the Jepara chairs observer, observation to some centres and workshops of Jepara chairs, literature study from various books consisting the style and process of Jepara chairs production were conducted. The identification of Jepara chairs started with Islamic and Hinduism influence in the 16th to the 17th century when the missionary and sailor from Portuguese entered Java until the style of Jepara chair in the 20th century. The alteration that mirrors the changes in socio-cultural aspect was being analysed as the style foundation that was used periodically in the making of the Jepara chairs. The categories a chair to have a Jepara style is a chair made by the craftsman in Jepara that, includes local factors both technically and material based that is combined with foreign culture, religion, and designs that brought at the time the chairs have been made. This research finds that chairs with Jepara style are a combination of the international world with a glimpse of local wisdom, with a touch of the maker’s personality that makes it unique and a bit different with its origin style. 

  19. On LAM's and SAM's for Halley's rotation

    Science.gov (United States)

    Peale, Stanton J.

    1992-01-01

    Non principal axis rotation for comet Halley is inferred from dual periodicities evident in the observations. The modes where the spin axis precesses around the axis of minimum moment of inertia (long axis mode or LAM) and where it precesses around the axis of maximum moment of inertia (short axis mode or SAM) are described from an inertial point of view. The currently favored LAM model for Halley's rotation state satisfies observational and dynamical constraints that apparently no SAM can satisfy. But it cannot reproduce the observed post perihelion brightening through seasonal illumination of localized sources on the nucleus, whereas a SAM can easily produce post or pre perihelion brightening by this mechanism. However, the likelihood of a LAM rotation for elongated nuclei of periodic comets such as Halley together with Halley's extreme post perihelion behavior far from the Sun suggest that Halley's post perihelion brightening may be due to effects other than seasonal illumination of localized sources, and therefore such brightening may not constrain its rotation state.

  20. A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance

    Directory of Open Access Journals (Sweden)

    Zhang Shunpu

    2007-06-01

    Full Text Available Abstract Background The Significance Analysis of Microarrays (SAM is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR. Recently, it has been reported in the literature that the FDR is not well controlled by SAM. Due to the vast application of SAM in microarray data analysis, it is of great importance to have an extensive evaluation of SAM and its associated R-package (sam2.20. Results Our study has identified several discrepancies between SAM and sam2.20. One major difference is that SAM and sam2.20 use different methods for estimating FDR. Such discrepancies may cause confusion among the researchers who are using SAM or are developing the SAM-like methods. We have also shown that SAM provides no meaningful estimates of FDR and this problem has been corrected in sam2.20 by using a different formula for estimating FDR. However, we have found that, even with the improvement sam2.20 has made over SAM, sam2.20 may still produce erroneous and even conflicting results under certain situations. Using an example, we show that the problem of sam2.20 is caused by its use of asymmetric cutoffs which are due to the large variability of null scores at both ends of the order statistics. An obvious approach without the complication of the order statistics is the conventional symmetric cutoff method. For this reason, we have carried out extensive simulations to compare the performance of sam2.20 and the symmetric cutoff method. Finally, a simple modification is proposed to improve the FDR estimation of sam2.20 and the symmetric cutoff method. Conclusion Our study shows that the most serious drawback of SAM is its poor estimation of FDR. Although this drawback has been corrected in sam2.20, the control of FDR by sam2.20 is still not satisfactory. The comparison between sam2.20 and the symmetric cutoff method reveals that the relative performance of sam2.20 to the symmetric cutff method depends on the

  1. Type 2 diabetes sits in a chair

    DEFF Research Database (Denmark)

    Solomon, Thomas; Thyfault, J P

    2013-01-01

    The incidence of type 2 diabetes (T2D) continues to skyrocket across the industrialized world leading to soaring medical costs, reduced quality of life and increased mortality rates. Therefore, a more firm understanding of the development of the disease and effective, low cost therapies....... In this review, we cover these topics and use current scientific evidence to support our belief that 'type 2 diabetes sits in a chair'. We also discuss a relatively new question that has yet to be examined: Would reducing sitting time be an effective treatment for T2D?...

  2. System Advisor Model, SAM 2014.1.14: General Description

    Energy Technology Data Exchange (ETDEWEB)

    Blair, Nate [National Renewable Energy Lab. (NREL), Golden, CO (United States); Dobos, Aron P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Freeman, Janine [National Renewable Energy Lab. (NREL), Golden, CO (United States); Neises, Ty [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wagner, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ferguson, Tom [Global Resources, Northbrook, IL (United States); Gilman, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Janzou, Steven [Janzou Consulting, Idaho Springs, CO (United States)

    2014-02-01

    This document describes the capabilities of the U.S. Department of Energy and National Renewable Energy Laboratory's System Advisor Model (SAM), Version 2013.9.20, released on September 9, 2013. SAM is a computer model that calculates performance and financial metrics of renewable energy systems. Project developers, policy makers, equipment manufacturers, and researchers use graphs and tables of SAM results in the process of evaluating financial, technology, and incentive options for renewable energy projects. SAM simulates the performance of photovoltaic, concentrating solar power, solar water heating, wind, geothermal, biomass, and conventional power systems. The financial model can represent financial structures for projects that either buy and sell electricity at retail rates (residential and commercial) or sell electricity at a price determined in a power purchase agreement (utility). SAM's advanced simulation options facilitate parametric and sensitivity analyses, and statistical analysis capabilities are available for Monte Carlo simulation and weather variability (P50/P90) studies. SAM can also read input variables from Microsoft Excel worksheets. For software developers, the SAM software development kit (SDK) makes it possible to use SAM simulation modules in their applications written in C/C++, C#, Java, Python, and MATLAB. NREL provides both SAM and the SDK as free downloads at http://sam.nrel.gov. Technical support and more information about the software are available on the website.

  3. General Quality Control (QC) Guidelines for SAM Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  4. Interview with Mr Bernard Dormy, Chair of TREF, in November 2017

    CERN Multimedia

    Staff Association

    2018-01-01

    Mr Bernard Dormy finished his term of office as the Chair of the Tripartite Employment Conditions Forum (TREF) (see Echo No. 242) at the end of 2017. On this occasion, the Staff Association met with him to discuss CERN and its personnel and, amongst other things, the model for concertation. Moreover, the Staff Association would like to take this opportunity to applaud Mr Dormy for the commitment he has shown since 2003, when he first started at TREF as a delegate of France. It is easy to believe that Mr Dormy found his mandate in this Forum particularly pleasing, since he served as the Vice-Chair of TREF from 2007 to 2011, and then as the Chairman from 2012 to 2017. During his chairmanship, Mr Dormy always made sure that the concertation took place under the best possible conditions, in a constructive manner and in a spirit of mutual respect. Furthermore, he placed great emphasis on diversity at CERN: there was not a single TREF meeting without an update on diversity issues and progress ma...

  5. Secondary School Department Chairs Leading Successful Change

    Directory of Open Access Journals (Sweden)

    Julie Ann Gaubatz

    2015-12-01

    Full Text Available A foundational understanding within education leadership literature is that education leaders are expected to guide reform efforts within school. This expectation mirrors organizational development literature that describes leaders as individuals who constructively institute change within their organizations. Although leadership and change are portrayed as codependent, no scholarship has linked change models with leadership theories. This article describes a multiple case study that explored the relationship between leadership behaviors and the change process through secondary school department chair stories of change. From this analysis, a clearer picture emerged that illustrates how leaders with little control over decisions implement change. Findings included distinct connections between CREATER change process stages and the Leadership Grid. Suggestions as to how education leaders should approach change attempts within their schools are discussed.

  6. A qualitative study of faculty members' views of women chairs.

    Science.gov (United States)

    Isaac, Carol; Griffin, Lindsay; Carnes, Molly

    2010-03-01

    Concurrent with the evolving role of the department chair in academic medicine is the entry of women physicians into chair positions. Because implicit biases that stereotypically masculine behaviors are required for effective leadership remain strong, examining faculty members' perceptions of their chair's leadership in medical school departments with women chairs can provide insight into the views of women leaders in academic medicine and the complex ways in which gender may impact these chairs' leadership style and actions. We conducted semistructured interviews with 13 male and 15 female faculty members representing all faculty tracks in three clinical departments chaired by women. Inductive, qualitative analysis of the subsequent text allowed themes to emerge across interviews. Four themes emerged regarding departmental leadership. One dealt with the leadership of the previous chair. The other three described the current chair's characteristics (tough, direct, and transparent), her use of communal actions to help support and mentor her faculty, and her ability to build power through consensus. Because all three chairs were early in their tenure, a wait and see attitude was frequently expressed. Faculty generally viewed having a woman chair as an indication of positive change, with potential individual and institutional advantages. This exploratory study suggests that the culture of academic medicine has moved beyond questioning women physicians' competence to lead once they are in top organizational leadership positions. The findings are also consonant with experimental research indicating that women leaders are most successful when they pair stereotypic male (agentic) behaviors with stereotypic female (communal) behaviors. All three chairs exhibited features of a transformational leadership style and characteristics deemed essential for effective leadership in academic medicine.

  7. Pediatric dental chair vs. traditional dental chair: A pediatric dentist′s poll

    OpenAIRE

    Khushboo Barjatya; Ankur Vatsal; Halaswamy V Kambalimath; Vinay Kumar Kulkarni; Naveen Banda Reddy

    2015-01-01

    Objective: Proper positioning of the child patient, can not only have positive ramifications for the operator′s posture, comfort, and career longevity - it can also lead to better treatment and increased productivity. The aim of the survey questionnaire was to assess the utilization, need, and attitude concerning dental chairs among pediatric dentist while working on and managing the child patient. Study Design: The questions were structured using adobe forms central online software, regardin...

  8. TABLE AND CHAIRS CRAFTSMAN IBM IN BULADU VILLAGE GORONTALO DISTRICT

    Directory of Open Access Journals (Sweden)

    Ayuddin Ayuddin

    2017-04-01

    Full Text Available The Gorontalo Community still rely on tables and chairs furniture made from rattan, but along with the time, tables and chairs from rattan is already becoming obsolete, one reason is growing furniture design that more convincing than other materials such as wood and aluminum. The society Devotion (IBM will provide re-design solutions for a table and chairs made from rattan by considering three main concepts, namely efficiency, aesthetic, and functional. With this concept can produce tables and chairs that are more innovative, powerful, and has a higher aesthetic so that it becomes a product of superior competition. Specific targets to be achieved is the increase: 1 knowledge and skills about designing tables and chairs from rattan using three concepts, namely efficiency, aesthetic, and functional, 2 increased revenue artisans from rattan tables and chairs. In addition to these targets, also the administrative improvement craftsmen and marketing management. The method used is the training and assistance directly to the artisans of the strategies and techniques in the manufacture of tables and chairs made of rattan. The results are expected to be an increase in the sale price so that the welfare of artisans tables and chairs to be better in the future.

  9. Academy – Springer Nature chair | About IASc | Indian Academy of ...

    Indian Academy of Sciences (India)

    Academy – Springer Nature Chair. Academy – Springer Nature chair. Background. The Indian Academy of Sciences and Springer mutually agreed to co-publish the Academy's ten journals and executed an agreement in the year 2006. To enhance the scope of its activities, the Academy formed the Academy Trust (tAcT), ...

  10. Exploring the Tensions and Ambiguities of University Department Chairs

    Science.gov (United States)

    Armstrong, Denise E.; Woloshyn, Vera E.

    2017-01-01

    The department chair is a complex middle-management position located at the organizational fulcrum between faculty and senior administration. This qualitative study sought to develop a deeper understanding of chairs' experiences when enacting their dual roles as managers and scholars. Using a basic interpretative study design, we interviewed 10…

  11. Women chairs in academic medicine: engendering strategic intuition.

    Science.gov (United States)

    Isaac, Carol; Griffin, Lindsay

    2015-01-01

    Because stereotypically masculine behaviors are required for effective leadership, examining female chairs' leadership in academic medicine can provide insight into the complex ways in which gender impacts on their leadership practices. The paper aims to discuss this issue. The author interviewed three female clinical chairs and compared the findings to interviews with 28 of their faculty. Grounded theory analysis of the subsequent text gathered comprehensive, systematic, and in-depth information about this case of interest at a US top-tier academic medical center. Four of five themes from the faculty were consistent with the chair's narrative with modifications: Prior Environment (Motivated by Excellence), Tough, Direct, Transparent (Developing Trust), Communal Actions (Creating Diversity of Opinion), and Building Power through Consensus (an "Artful Exercise") with an additional theme, the Significance (and Insignificance) of a Female Chair. While faculty members were acutely aware of the chair's gender, the chairs paradoxically vacillated between gender being a "non-issue" and noting that male chairs "don't do laundry." All three female chairs in this study independently and explicitly stated that gender was not a barrier, yet intuitively used successful strategies derived from the research literature. This study suggests that while their gender was highlighted by faculty, these women dismissed gender as a "non-issue." The duality of gender for these three female leaders was both minimized and subtly affirmed.

  12. Highlight: Research Chair unites four West African universities in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-14

    Apr 14, 2016 ... Local and regional experts including researchers, consultants, and academics convened in Cotonou, Benin, on February 26, 2015 to launch a Research Chair on EcoHealth. The Chair unites four West African universities that have pledged to reduce air pollution and non-communicable respiratory ...

  13. Highlight: Research Chair unites four West African universities in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2015-02-26

    2 févr. 2015 ... Local and regional experts including researchers, consultants, and academics convened in Cotonou, Benin, on February 26, 2015 to launch a Research Chair on EcoHealth. The Chair unites four West African universities that have pledged to reduce air pollution and non-communicable respiratory ...

  14. Perceptions of Interior Design Program Chairs Regarding Credentials for Faculty

    Science.gov (United States)

    Miller, Beth R.

    2017-01-01

    The purpose of this study was to determine whether program chairs in interior design have a preferred degree credential for candidates seeking a full-time, tenure-track position or other full-time position at their institution and to determine if there is a correlation between this preference and the program chair's university's demographics,…

  15. Turnover of First-Time Chairs in Departments of Psychiatry

    Science.gov (United States)

    Buckley, Peter F.; Rayburn, William F.

    2011-01-01

    Objective: The authors examine the tenure of first-time Chairs in academic departments of psychiatry in order to stimulate discussion on extant workforce and leadership issues. Method: Data on tenure of Chairs in psychiatry and other nonsurgical specialties were derived from the longitudinal database of the Association of American Medical Colleges…

  16. Storifying Samsøs Renewable Energy Transition

    DEFF Research Database (Denmark)

    Papazu, Irina

    2017-01-01

    Through a joint community effort Denmark’s Renewable Energy Island Samsø became self-sufficient with renewable energy over a period of 10 years from 1997 to 2007. Today, the story about Samsø’s successful energy transition has become a global export and a widely known model of community building......, public participation and shared ownership in renewable energy technologies and transition processes. What has allowed the Samsø narrative to travel so widely has been the effective ‘transition story’ created about the islanders’ efforts. This transition story, however, has become fixed with the years...... of further local energy transitions, as challenging elements of the process are downplayed to strengthen the narrative power of the story. Ethnographic stories about Samsø complicate the island’s transition narrative and add nuance to the Samsø story, highlighting its discrepancies and problematizing...

  17. Après la chair

    Directory of Open Access Journals (Sweden)

    Claude Romano

    2013-12-01

    Full Text Available Il n’y a pas de question plus urgente, pour la phénoménologie, que la question du « corps propre », comme il est convenu de l’appeler depuis Husserl. Mais il n’y a pas non plus de question qui ait été davantage négligée par les phénoménologues contemporains. À première vue, cette affirmation se heurte à l’évidence d’une production littéraire quasi exponentielle autour de cette notion depuis plus d’une trentaine d’années, aussi bien en histoire de la philosophie que dans des travaux qui se sont efforcés de croiser la perspective phénoménologique avec les apports des sciences du cerveau et de la cognition. L’ennui est que cette ample littérature ne pose aucune des questions préjudicielles à l’adoption du concept de corps propre ou de chair (Leib en phénoménologie ; pour l’essentiel, elle fait comme si ce concept allait de soi et se borne à se demander de quelle manière il pourrait « féconder » des approches scientifiques plus positives. La légitimité du concept même de Leib et de ses prolongements à l’intérieur du courant phénoménologique n’y est jamais questionnée en tant que telle. Non seulement on ne se demande pas si les descriptions de cette « chair » au fil conducteur de l’expérience du toucher redoublé est tenable, mais on ne soulève même pas la question de savoir si l’adoption de ce concept chez Husserl et ses successeurs n’est pas conditionnée par des présupposés discutables et, en vérité, par tout un cadre théorique, de sorte que la mise en question de certains aspects centraux de ce cadre devrait conduire inévitablement à une révision en profondeur de ce concept. C’est cette question que nous voudrions aborder dans ces pages. Compte-tenu de l’ampleur du sujet, notre but sera uniquement d’indiquer un certain nombre de directions que pourrait – ou devrait – emprunter la réflexion.

  18. Vices Among Commercial Chickens in Maiduguri, Borno State ...

    African Journals Online (AJOL)

    A survey was carried out to determine the presence of vices in commercial chickens in Maiduguri, Borno State, between Marchto July, 2005. Types, causes, and possible control measures were also investigated. Forty flocks were randomly selected and studied. These included institutional, government and private (small ...

  19. Vice's Vicious Virtues: The Supererogatory as Obligatory | Mills ...

    African Journals Online (AJOL)

    ... both in its enduring socio-economic structures and in its citizens' typical moral psychologies. Vice's conclusion is that shame is the moral emotion most appropriate for whites unable to free themselves from white privilege and live up to what she sees as the required standards of moral excellence. In response, I argue that ...

  20. Vice-Principalship: Their Responsibility Roles and Career Aspirations

    Science.gov (United States)

    Lee, John Chi-Kin; Kwan, Paula; Walker, Allan

    2009-01-01

    A discrepancy exists between the ideal and the actual roles played by vice-principals (VPs). This gap between roles influences the level of job satisfaction, which, in turn, affects their desire for a principalship. This study used a questionnaire survey of about 300 Hong Kong VPs to examine the core responsibility dimensions pertaining to their…

  1. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    ... to 2017-10-13. Destination(s):. Cairo, Egypt. Airfare: $4,512.88. Other. Transportation: $118.45. Accommodation: $494.52. Meals and. Incidentals: $300.00. Other: $114.20. Total: $5,540.05. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  2. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    BB

    2017-06-11 to 2017-06-14. Destination(s):. Montreal. Airfare: $0.00. Other. Transportation: $170.23. Accommodation: $793.75. Meals and. Incidentals: $103.67. Other: $0.00. Total: $1,067.65. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  3. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    2017-11-14 to 2017-11-15. Destination(s):. Calgary. Airfare: $468.90. Other. Transportation: $118.90. Accommodation: $223.42. Meals and. Incidentals: $116.64. Other: $46.00. Total: $973.86. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  4. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    BB

    Destination(s):. Guatemala/Honduras. Airfare: $3,069.59. Other. Transportation: $317.65. Accommodation: $2,136.60. Meals and. Incidentals: $532.40. Other: $0.00. Total: $6,056.24. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  5. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Date(s):. 2017-10-27. Destination(s):. Montreal. Airfare: $0.00. Other. Transportation: $315.96. Accommodation: $0.00. Meals and. Incidentals: $25.92. Other: $16.00. Total: $357.88. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  6. 2017-2018 Travel Expense Reports for Joanne Charette, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Destination(s):. Kenya, Uganda and Tanzania. Airfare: $5,885.73. Other. Transportation: $70.60. Accommodation: $2,983.48. Meals and. Incidentals: $1,053.24. Other: $334.93. Total: $10,327.98. Comments: 2017-2018 Travel Expense Reports for Joanne. Charette, Vice-President, Corporate Strategy and Communications.

  7. Providing output of DIRAC-SAM jobs to the IT-based SAM-Nagios framework

    CERN Document Server

    Volkl, Valentin

    2013-01-01

    Information available on LHCb grid sites in the SAM-Nagios monitor- ing framework - gathered mainly through functional tests - has been sup- plemented with results from LHCbDIRAC SAMJobs published by means of message client newly integrated in LHCbDIRAC. These are displayed as a new metric org.lhcb.DiracTest-lhcb giving additional debug in- formation to system administrators and influencing reports on grid site performances in the future

  8. Sitting into the limelight: Lonely Chairs at CERN turns one

    CERN Multimedia

    Katarina Anthony

    2015-01-01

    A picture may be worth a thousand words - but a picture of a chair? It’s worth a story all by itself. Over the past year, the "Lonely Chairs at CERN" photography blog has let the chairs do the talking. Along the way, these chairs have inspired and enchanted people across the globe with their honest depiction of the Laboratory.   This lonely chair outside Building 32 was one of the first Rebeca photographed. When CMS physicist Rebeca Gonzalez Suarez created Lonely Chairs at CERN back in April 2014, she was not expecting the immediate reaction it garnered. Within days, the blog had picked up thousands of followers and was featured in Gizmodo and The Guardian. "The response inside CERN was very positive, but the response outside was overwhelming," says Rebeca. "I’ve got a lot of followers who are really into science and are very excited about CERN. They comment about wanting to work here - sometimes on the ugliest chair I&rsqu...

  9. Burnout in United States Academic Chairs of Radiation Oncology Programs

    Energy Technology Data Exchange (ETDEWEB)

    Kusano, Aaron S. [Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington (United States); Thomas, Charles R., E-mail: thomasch@ohsu.edu [Department of Radiation Medicine, Knight Cancer Institute/Oregon Health and Science University, Portland, Oregon (United States); Bonner, James A. [Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama (United States); DeWeese, Theodore L. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland (United States); Formenti, Silvia C. [Department of Radiation Oncology, New York University, New York, New York (United States); Hahn, Stephen M. [Department of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (United States); Lawrence, Theodore S. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan (United States); Mittal, Bharat B. [Department of Radiation Oncology, Northwestern University, Chicago, Ilinois (United States)

    2014-02-01

    Purpose: The aims of this study were to determine the self-reported prevalence of burnout in chairs of academic radiation oncology departments, to identify factors contributing to burnout, and to compare the prevalence of burnout with that seen in other academic chair groups. Methods and Materials: An anonymous online survey was administered to the membership of the Society of Chairs of Academic Radiation Oncology Programs (SCAROP). Burnout was measured with the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Results: Questionnaires were returned from 66 of 87 chairs (76% response rate). Seventy-nine percent of respondents reported satisfaction with their current positions. Common major stressors were budget deficits and human resource issues. One-quarter of chairs reported that it was at least moderately likely that they would step down in the next 1 to 2 years; these individuals demonstrated significantly higher emotional exhaustion. Twenty-five percent of respondents met the MBI-HSS criteria for low burnout, 75% for moderate burnout, and none for high burnout. Group MBI-HSS subscale scores demonstrated a pattern of moderate emotional exhaustion, low depersonalization, and moderate personal accomplishment, comparing favorably with other specialties. Conclusions: This is the first study of burnout in radiation oncology chairs with a high response rate and using a validated psychometric tool. Radiation oncology chairs share similar major stressors to other chair groups, but they demonstrate relatively high job satisfaction and lower burnout. Emotional exhaustion may contribute to the anticipated turnover in coming years. Further efforts addressing individual and institutional factors associated with burnout may improve the relationship with work of chairs and other department members.

  10. Cranial nerves neuropraxia after shoulder arthroscopy in beach chair position.

    Science.gov (United States)

    Cogan, A; Boyer, P; Soubeyrand, M; Hamida, F Ben; Vannier, J-L; Massin, P

    2011-05-01

    We report a case of neuropraxia of the 9th, 10th and 12th cranial nerve pairs after arthroscopic rotator cuff repair in the beach chair position. The elements in the medical file seem to exclude an intracranial cause of the lesions and support a mechanical, extracranial cause due to intubation and/or the beach chair position. This clinical case report shows the neurological risks of the beach chair position during arthroscopic shoulder surgery and presents the essential safety measures to prevent these risks. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  11. Spirit Pluralisme dalam Klenteng Sam Po Kong Semarang

    Directory of Open Access Journals (Sweden)

    Edi Nurwahyu Julianto

    2015-07-01

    Full Text Available Klenteng Sam Po Kong has very deep meaning as a symbol of multi cultural; multi ethnic and multi religious. Klenteng Sam Po Kong has a different function, not only used by people with background religious Tri Dharma (Budha, Tao and Konghuchu, but also used by Javanese ethnic with different religious backgrounds. Between ethnic China and Java, mutual respect and tolerance run beliefs and rituals of each. More over, Klenteng Sam Po Kong is a form of pluralism which reflected the fact Sino Javanese Muslim Culture is preserved to date both of sightings physical culture and system cultural in the form of religious rites performed by ethnic China and Java.

  12. Crystal structures of the SAM-III/S[subscript MK] riboswitch reveal the SAM-dependent translation inhibition mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Lu, C.; Smith, A.M.; Fuchs, R.T.; Ding, F.; Rajashankar, K.; Henkin, T.M.; Ke, A. (Cornell); (OSU)

    2010-01-07

    Three distinct classes of S-adenosyl-L-methionine (SAM)-responsive riboswitches have been identified that regulate bacterial gene expression at the levels of transcription attenuation or translation inhibition. The SMK box (SAM-III) translational riboswitch has been identified in the SAM synthetase gene in members of the Lactobacillales. Here we report the 2.2-{angstrom} crystal structure of the Enterococcus faecalis SMK box riboswitch. The Y-shaped riboswitch organizes its conserved nucleotides around a three-way junction for SAM recognition. The Shine-Dalgarno sequence, which is sequestered by base-pairing with the anti-Shine-Dalgarno sequence in response to SAM binding, also directly participates in SAM recognition. The riboswitch makes extensive interactions with the adenosine and sulfonium moieties of SAM but does not appear to recognize the tail of the methionine moiety. We captured a structural snapshot of the SMK box riboswitch sampling the near-cognate ligand S-adenosyl-L-homocysteine (SAH) in which SAH was found to adopt an alternative conformation and fails to make several key interactions.

  13. Highlight: Kenya selects first research chair on health systems ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-14

    NACOSTI), in collaboration with IDRC, launched Kenya's first Research Chair on March 31, 2015 in Nairobi. Professor Fabian Omoding Esamai, the current Principal of Moi University's College of Health Sciences, has been selected ...

  14. The Department Chair during Fiscal Constraints: Visionary Shop Foreman.

    Science.gov (United States)

    Horton, Susan R.

    1994-01-01

    Considers the role of the English department head in a time of fiscal constraint and retrenchment. Describes the special responsibilities necessitated by lean financial circumstances. Discusses department/administration relations and the public relations aspect of chairing a department. (HB)

  15. Benchmarking Academic Anatomic Pathologists: The Association of Pathology Chairs Survey

    National Research Council Canada - National Science Library

    Ducatman, Barbara S; Parslow, Tristram

    2016-01-01

    .... We examined the Association of Pathology Chairs annual faculty productivity data and compared it with MGMA and FPSC data to understand the value, inherent flaws, and limitations of benchmarking data...

  16. SAM Chlorine Observations at Gale Crater

    Science.gov (United States)

    Conrad, P. G.; Farley, K. A.; Vasconcelos, P. M.; Malespin, C.; Franz, H.; McAdam, A.; Sutter, B.; Stern, J. C.; Clark, B. C.; Atreya, S. K.; Mahaffy, P. R.; Martín-Torres, J.; Zorzano, M. P.

    2014-12-01

    The Sample Analysis at Mars investigation has detected Cl-bearing phases of various oxidation states in its thermally evolved gas measurements of both a wind drift deposit of fines and three different rock samples delivered as sieved drill powders to the instrument suite. In addition to HCl (Leshin et al, 2013; Ming et al, 2013) and chlorinated hydrocarbon detections (Glavin et al, 2013; Freissinet et al, in review), oxygen releases consistent with the decomposition of perchlorate salts are also observed. We have also measured chlorine isotope ratios of the four different solid samples, which yielded variable and more negative δ37Cl than typically observed in SNC meteorite analyses. We summarize our chlorine observations in the context of other gases observed in the SAM solid sample analyses, including water, sulfur- and nitrogen-bearing compounds, and REMS observations of Relative Humidity and Temperature, and compare with knowledge of martian chlorine obtained from the SNC meteorites. Finally, we examine the implications of surface/atmosphere Cl interactions and isotopic ratios for the rise and decline of habitable surface environments on Mars. This research was supported by the National Aeronautics and Space Administration (NASA) Mars Science Laboratory mission.

  17. Sam D. Hamilton Noxubee National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Sam D. Hamilton Noxubee NWR for the next 15 years. This plan outlines the Refuge vision...

  18. Recent Updates to the System Advisor Model (SAM)

    Energy Technology Data Exchange (ETDEWEB)

    DiOrio, Nicholas A [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-02-14

    The System Advisor Model (SAM) is a mature suite of techno-economic models for many renewable energy technologies that can be downloaded for free as a desktop application or software development kit. SAM is used for system-level modeling, including generating performance pro the release of the code as an open source project on GitHub. Other additions that will be covered include the ability to download data directly into SAM from the National Solar Radiation Database (NSRDB) and up- dates to a user-interface macro that assists with PV system sizing. A brief update on SAM's battery model and its integration with the detailed photovoltaic model will also be discussed. Finally, an outline of planned work for the next year will be presented, including the addition of a bifacial model, support for multiple MPPT inputs for detailed inverter modeling, and the addition of a model for inverter thermal behavior.

  19. General Safety and Waste Management Related to SAM

    Science.gov (United States)

    The General Safety and Waste Management page offers section-specific safety and waste management details for chemicals, radiochemicals, pathogens, and biotoxins included in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  20. Safety and Waste Management for SAM Chemistry Methods

    Science.gov (United States)

    The General Safety and Waste Management page offers section-specific safety and waste management details for the chemical analytes included in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  1. Safety and Waste Management for SAM Pathogen Methods

    Science.gov (United States)

    The General Safety and Waste Management page offers section-specific safety and waste management details for the pathogens included in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  2. Safety and Waste Management for SAM Radiochemical Methods

    Science.gov (United States)

    The General Safety and Waste Management page offers section-specific safety and waste management details for the radiochemical analytes included in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  3. Technical Manual for the SAM Physical Trough Model

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, M. J.; Gilman, P.

    2011-06-01

    NREL, in conjunction with Sandia National Lab and the U.S Department of Energy, developed the System Advisor Model (SAM) analysis tool for renewable energy system performance and economic analysis. This paper documents the technical background and engineering formulation for one of SAM's two parabolic trough system models in SAM. The Physical Trough model calculates performance relationships based on physical first principles where possible, allowing the modeler to predict electricity production for a wider range of component geometries than is possible in the Empirical Trough model. This document describes the major parabolic trough plant subsystems in detail including the solar field, power block, thermal storage, piping, auxiliary heating, and control systems. This model makes use of both existing subsystem performance modeling approaches, and new approaches developed specifically for SAM.

  4. Kuula. Kuu artist Sam Sparro. Kuu plaat / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2008-01-01

    Artistist Sam Sparrost. Heliplaatidest: "Sex And The City" Original Motion Picture Soundtrack, "Maestro: Blue Note Trip", Melvin/Soo/Remmel/Julm "Geografix", Alanis Morrisette "Flavors Of Entanglement", Guillemots "Red"

  5. Sam Wagstaffi unustatud kired / Ahto Külvet

    Index Scriptorium Estoniae

    Külvet, Ahto

    2008-01-01

    Dokumentaalfilm "Black, White & Gray: Sam Wagstaff and Robert Mapplethorpe" : autor ja režissöör James Crump : Ameerika Ühendriigid 2007. Filmi näidati filminädala "Art in America" raames Tallinnas

  6. Influence of Chair Vibrations on Indoor Sonic Boom Annoyance

    Science.gov (United States)

    Rathsam, Jonathan; Klos, Jacob; Loubeau, Alexandra

    2015-01-01

    One goal of NASA’s Commercial Supersonic Technology Project is to identify candidate noise metrics suitable for regulating quiet sonic boom aircraft. A suitable metric must consider the short duration and pronounced low frequency content of sonic booms. For indoor listeners, rattle and creaking sounds and floor and chair vibrations may also be important. The current study examined the effect of such vibrations on the annoyance of test subjects seated indoors. The study involved two chairs exposed to nearly identical acoustic levels: one placed directly on the floor, and the other isolated from floor vibrations by pneumatic elastomeric mounts. All subjects experienced both chairs, sitting in one chair for the first half of the experiment and the other chair for the remaining half. Each half of the experiment consisted of 80 impulsive noises played at the exterior of the sonic boom simulator. When all annoyance ratings were analyzed together there appeared to be no difference in mean annoyance with isolation condition. When the apparent effect of transfer bias was removed, a subtle but measurable effect of vibration on annoyance was identified.

  7. Classroom furniture design--correlation of pupil and chair dimensions.

    Science.gov (United States)

    Domljan, Danijela; Grbac, Ivica; Hadina, Julijana

    2008-03-01

    The present study aimed at determining the relationship of anthropometric dimensions of pupils from grades 1 to 8 in primary school with the dimensions of school chairs. Two dimensions of the chairs in daily use were evaluated to ascertain whether the fit is sufficient and the effect on pupils' sitting posture. The work included a sample of 556 pupils from three primary schools in Zagreb, Croatia and two types of furniture. Dimensions of school chairs were compared with three anthropometric variables of the pupils. Descriptive statistics were analysed for all variables. These study results have shown that furniture of appropriate dimensions is not available to a large number of students in Croatia. Currently supplied classroom equipment is provided in only two sizes and does not fit the users. It is recommended that task chairs may be acceptable if they are issued in four heights or individually adjustable chairs be introduced in Croatian schools. Furthermore it is strongly recommended that schools actively promote appropriate active sitting behaviour.

  8. Women chairs in academic medicine: engendering strategic intuition

    Science.gov (United States)

    Isaac, Carol; Griffin, Lindsay

    2017-01-01

    Purpose Because stereotypically masculine behaviors are required for effective leadership, examining female chairs’ leadership in academic medicine can provide insight into the complex ways in which gender impacts on their leadership practices. The paper aims to discuss this issue. Design/methodology/approach The author interviewed three female clinical chairs and compared the findings to interviews with 28 of their faculty. Grounded theory analysis of the subsequent text gathered comprehensive, systematic, and in-depth information about this case of interest at a US top-tier academic medical center. Findings Four of five themes from the faculty were consistent with the chair’s narrative with modifications: Prior Environment (Motivated by Excellence), Tough, Direct, Transparent (Developing Trust), Communal Actions (Creating Diversity of Opinion), and Building Power through Consensus (an “Artful Exercise”) with an additional theme, the Significance (and Insignificance) of a Female Chair. While faculty members were acutely aware of the chair’s gender, the chairs paradoxically vacillated between gender being a “non-issue” and noting that male chairs “don’t do laundry.” All three female chairs in this study independently and explicitly stated that gender was not a barrier, yet intuitively used successful strategies derived from the research literature. Originality/value This study suggests that while their gender was highlighted by faculty, these women dismissed gender as a “non-issue.” The duality of gender for these three female leaders was both minimized and subtly affirmed. PMID:26045192

  9. Book Review: Higher Education, Leadership and Women Vice Chancellors

    Directory of Open Access Journals (Sweden)

    Pamela L. Eddy

    2016-10-01

    Full Text Available The paucity of women leaders in higher education continues despite advancement by women in other fronts of the educational pipeline.  Today, more women are attending and graduating from college in the United States, but something occurs en route to the top-level leadership positions in these same college settings.  The portrait of college leaders continues to consist of White men, as it has since the initial founding of universities.  Paula Burkinshaw analyzes the situation of the missing women leaders in the United Kingdom, specifically in the position of Vice Chancellor.  Burkinshaw’s long career in leadership development in university settings initially provided her with an awareness of the underrepresentation of women in top leadership positions.  As she began her doctoral studies, she had an opportunity to ask “where are the women?”  Her book builds on her dissertation research, which involved one-on-one interviews with 18 women who were vice chancellors.

  10. Ensuring GRID resource availability with the SAM framework in LHCb

    Science.gov (United States)

    Closier, J.; Paterson, S.; Santinelli, R.

    2008-07-01

    The LHCb experiment has chosen to use the SAM framework (Service Availability Monitoring Environment from EGEE-II) [1] make extensive tests of the LHCb environment at all the accessible grid resources. The availability and the proper definition of the local Computing and Storage Elements, user interfaces as well as the WLCG software environment are checked. The SAM framework is also used to pre-install the LHCb applications in the shared software area provided by each site. The deployment of the LHCb applications is based on a python tool developed inside the experiment. It is used for software management including incremental installation of interdependent packages and clean package removal. After the application software is installed a validation test of the whole MC chain is run. According to the results of the experiment specific SAM tests, the sites are (re)integrated into the LHCb production system managed by DIRAC [2]. The possibility of automated dynamic site certification using the SAM test suite is explored. This paper will describe the various ways of the LHCb use of the SAM framework. Practical experience in the recent production runs, current limitations and future developments will be presented.

  11. Analysis of Sabine and Eyring equations and their application to concert hall audience and chair absorption.

    Science.gov (United States)

    Beranek, Leo L

    2006-09-01

    Historically, two equations have been used for predicting reverberation times, Sabine and Eyring. A precise means is presented for determining Eyring absorption coefficients alpha(eyring) when the Sabine coefficients alpha(sabine) are known, and vice versa. Thus, either formula can be used provided the absorption coefficients for the Sabine formula are allowed to exceed 1.0. The Sabine formula is not an approximation to the Eyring equation and is not a shortcoming. Given low reverberation times, the ratio of alpha(sabine) to alpha(eyring) may become greater than 2.0. It is vital that, for correct prediction of reverberation times, the absorption coefficients used in either formula must have been determined in spaces similar in size and shape, with similar locations of high absorption (audience) areas, and with similar reverberation times. For concert halls, it is found that, when the audience area (fully occupied) and midfrequency reverberation time are postulated, the hall volume is directly proportional to the audience absorption coefficient. Approximately 6% greater room volumes are needed when choosing nonrectangular versus classical-rectangular shaped halls and approximately 10% greater volumes when choosing heavily upholstered versus medium upholstered chairs. Determinations of audience sound absorption coefficients are presented, based on published acoustical and architectural data for 20 halls.

  12. Native interface of the SAM domain polymer of TEL

    Directory of Open Access Journals (Sweden)

    Bowie James U

    2002-08-01

    Full Text Available Abstract Background TEL is a transcriptional repressor containing a SAM domain that forms a helical polymer. In a number of hematologic malignancies, chromosomal translocations lead to aberrant fusions of TEL-SAM to a variety of other proteins, including many tyrosine kinases. TEL-SAM polymerization results in constitutive activation of the tyrosine kinase domains to which it becomes fused, leading to cell transformation. Thus, inhibitors of TEL-SAM self-association could abrogate transformation in these cells. In previous work, we determined the structure of a mutant TEL-SAM polymer bearing a Val to Glu substitution in center of the subunit interface. It remained unclear how much the mutation affected the architecture of the polymer, however. Results Here we determine the structure of the native polymer interface. To accomplish this goal, we introduced mutations that block polymer extension, producing a heterodimer with a wild-type interface. We find that the structure of the wild-type polymer interface is quite similar to the mutant structure determined previously. With the structure of the native interface, it is possible to evaluate the potential for developing therapeutic inhibitors of the interaction. We find that the interacting surfaces of the protein are relatively flat, containing no obvious pockets for the design of small molecule inhibitors. Conclusion Our results confirm the architecture of the TEL-SAM polymer proposed previously based on a mutant structure. The fact that the interface contains no obvious potential binding pockets suggests that it may be difficult to find small molecule inhibitors to treat malignancies in this way.

  13. Technoeconomic Modeling of Battery Energy Storage in SAM

    Energy Technology Data Exchange (ETDEWEB)

    DiOrio, Nicholas [National Renewable Energy Lab. (NREL), Golden, CO (United States); Dobos, Aron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Janzou, Steven [National Renewable Energy Lab. (NREL), Golden, CO (United States); Nelson, Austin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lundstrom, Blake [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    Detailed comprehensive lead-acid and lithium-ion battery models have been integrated with photovoltaic models in an effort to allow System Advisor Model (SAM) to offer the ability to predict the performance and economic benefit of behind the meter storage. In a system with storage, excess PV energy can be saved until later in the day when PV production has fallen, or until times of peak demand when it is more valuable. Complex dispatch strategies can be developed to leverage storage to reduce energy consumption or power demand based on the utility rate structure. This document describes the details of the battery performance and economic models in SAM.

  14. New chair for the Particle Physics and Astronomy Research Council

    CERN Multimedia

    2001-01-01

    Peter Warry has been appointed as Chair of PPARC for the next 4 years. Chairman of Victrex plc, whose business is in speciality chemicals, he has been an Industrial Professor at the University of Warwick since 1993. PPARC pursues a programme of high quality basic research in particle physics, astronomy, cosmology and space science and its budget for 2002 is approximately 220 million GBP.

  15. Gender, Performativity, and Leadership: Department Chairs in Research Universities

    Science.gov (United States)

    Lepkowski, Christine

    2014-01-01

    Women are significantly underrepresented as administrators in higher education leadership. This qualitative study examined the leadership of department chairs at public research universities to better understand how their gender and other identities affected their leadership. The following research questions shaped the study: (1) How do department…

  16. Highlight: Kenya selects first research chair on health systems ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 avr. 2016 ... Speaking about the Research Chair program, Dr Moses Rugutt, NACOSTI's Director General said, “Kenya, like many other African countries, suffers brain drain as professionals seek better remuneration and research facilities as well as funding opportunities abroad. This program is hinged on providing a ...

  17. Presidents and Chairs on Common Ground: Handling Flashpoints Together

    Science.gov (United States)

    Fletcher, Donald H.; Maxwell, David E.

    2011-01-01

    In the face of public controversies, presidents and board chairs are often called upon to resolve difficult and divisive issues. When they are faced with public controversies and other challenges, a strong working relationship grounded in mutual respect and trust can make the difference between meeting the challenge head on and falling behind.…

  18. Joining forces to find answers — The International Research Chairs ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-08

    Oct 8, 2010 ... Sharing skills and knowledge to confront real-world problems. Under the International Research Chairs Initiative, top specialists are sharing their advanced skills and knowledge to confront real-world problems in the areas of environment, health, and technology while mentoring a new generation of ...

  19. Jubilee Chair | About IASc | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Jubilee Chair. The Jubilee Professorship was instituted during the Platinum Jubilee Year of the Academy (2009). General guidelines are as follows: Eminent scientists from any country and from any scientific discipline can be invited to occupy the Jubilee Professorship for a minimum period of two weeks and up to one ...

  20. Development of Leadership Skills in Community College Department Chairs

    Science.gov (United States)

    Sirkis, Jocelyn Eager

    2011-01-01

    The role of a community college department chairperson is not well defined and the job is often perceived as more of a burden than an honor. Faculty come to the position frequently by "default" and without a ready set of management and leadership skills. The matter is of concern since chairs influence academic department strategy, culture, and…

  1. Prof. Frank Shu | Academy – Springer Nature chair | About IASc ...

    Indian Academy of Sciences (India)

    Academy – Springer Nature chair. Prof Frank Shu. Prof. Frank Shu. Shu is known for pioneering theoretical work in a diverse set of fields of astrophysics, including the origin of meteorites, the birth and early evolution of stars and the structure of spiral galaxies. One of his most highly-cited works is a 1977 seminal paper ...

  2. Development of Cad Software for Wheel Chair Design | Ayodeji ...

    African Journals Online (AJOL)

    Anthropometric data of Nigerian paraplegics was used to design wheel chair for the paraplegics. This was done by developing suitable software using Visual Basic, AutoCAD, Access and Corel- Draw programs. The software developed is capable of designing an ergonomically viable wheelchair for any category of ...

  3. IDRC partner Carolina Trivelli elected chair of the Consultative ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-06-14

    Jun 14, 2017 ... IDRC congratulates Carolina Trivelli on her election as chair of the executive committee for the Consultative Group to Assist the Poor (CGAP) at the organization's annual meeting on May 18, 2017 in Yangon, Myanmar. She became a member of the executive committee in 2014. Housed at the World Bank, ...

  4. Reshaping Foreign Language Programs: Implications for Department Chairs.

    Science.gov (United States)

    Gay-Crosier, Raymond

    1987-01-01

    A chair of a university's department of Romance languages and literature addresses the status of two high priorities in the teaching of foreign languages: the integration of linguistics in the "new" curriculum; the continuing development of language teaching approaches in the classroom; and the commitment of foreign language programs in the…

  5. Ecohealth Chair on Human and Animal Health in Protected ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    There are also significant knowledge gaps on potential long-term effects on human and animal health, ecosystem sustainability, and costs and benefits of potential mitigation strategies. Through the Ecohealth Chair position, this project will foster a body of evidence and knowledge, research capacity, and collaboration to ...

  6. Chair interconversion and reactivity of mannuronic acid esters

    NARCIS (Netherlands)

    Ronnols, Jerk; Walvoort, Marthe T. C.; van der Marel, Gijsbert A.; Codee, Jeroen D. C.; Widmalm, Goran

    2013-01-01

    Mannopyranosyluronic acids display a very unusual conformation behavior in that they often prefer to adopt a C-1(4) chair conformation. They are endowed with a strikingly high reactivity when used in a glycosylation reaction as a glycosyl donor. To investigate the unusual conformational behavior a

  7. POSTWAR EUROPEAN CHAIR DESIGN. A COMEBACK OF THE STYLE CONNECTION

    Directory of Open Access Journals (Sweden)

    Marina CIONCA

    2015-12-01

    Full Text Available The paper presents the results of studies and research aimed at identifying significant concepts of the design process dynamics of two European designers, Gió Ponti (Italy and Hans Wegner (Denmark. Two of their major chair designs, the Wishbone Chair (Wegner, 1944-49 and the Superleggera Chair (Ponti, 1951-57 were chosen as study cases. Their historical concept sources were carefully investigated and documented, since in the postwar years a tendency towards disregarding the dogmatic functionality of the interwar avant-garde furniture design occurred, making place for a different kind of innovation that did not contradict the natural evolution of form and function, but introduced an inherent elegance of form, as well as exceptional craftsmanship seen as adding value to the industrial production. Formal, compositional, structural and ergonomic elements were analysed, measurements of dimensions and angles were made and compared, sitting positions were visualised, in an attempt to unveil crucial aspects of specific design insights. The good understanding of the style connections, of the significant construction details that confirm the innovative, functional and well-balanced appearance of these chairs, of the careful selection of materials that characterised postwar austerity, contributed to an already confirmed investigative approach, which may be seen as a useful instrument of knowledge not only for design education, but also for design historians, furniture designers, manufacturers and artisans.

  8. A new era begins: an official statement by Romanian Vice-Minister of Health Professor Bogdan Marinescu.

    Science.gov (United States)

    Marinescu, B

    1990-06-01

    Dr. Bogdan Marinescu, Vice-Minister of Health, is responsible for mother and child care, prevention and care in schools and universities, and the newly created Family Planning Unit. The repeal, on December 25, 1989, of the law on abortion created the legal environment for the implementation of a national family planning program (FPP). The new program will be offered to all women who want it. Special attention will be given to women having an abortion. The primary objectives of the overall FPP of the Ministry of Health consists of decreasing maternal mortality and morbidity caused by abortion and facilitating the switch from using abortion techniques to modern contraceptive techniques. The 1st step will be the nomination of a head of the FP unit who could be either a gynecologist or and administrator advised by a gynecologist. The unit head will immediately create an operational task force. The Vice-Minister will chair the task force, with the unite head acting as secretary. There will be 9 officers in the task force: the head of the FPP and a senior gynecologist from one of the teaching hospitals, and the senior nursing tutor from the post-basic training college for nurses, the senior FP health statistician, the head of health education, a representative from the Romanian FP association and a consumer. The main goal of the task force is to facilitate the development of the program by advising the Vice-Minister on all issues pertaining to FP. The creation, on April 3, 1990, of a Society for Education in Contraception (SECS) will facilitate communication among, and education of, the public and specific groups at risk, such as adolescents. The family planning program will be progressively established, starting with the university teaching hospitals, and spreading to district and town hospitals, then polyclinics. Only obstetricians and gynecologists will be allowed, at least during this 1st phase, to prescribe contraceptives. The new contraceptives introduced in the

  9. Human Research Program 2010 Chair Standing Review Panel Meeting

    Science.gov (United States)

    Steinberg, Susan

    2011-01-01

    The 13 Human Research Program (HRP) Standing Review Panel (SRP) Chairs, and in some cases one or two additional panel members (see section XIV, roster) referred to as the Chair (+1) SRP throughout this document, met at the NASA Johnson Space Center (JSC) on December 7, 2010 to allow the HRP Elements and Projects to report on their progress over the past year, their current status, and their plans for the upcoming year based on NASA's current goals and objectives for human space exploration. A large focus of the meeting was also used to discuss integration across the HRP scientific disciplines based on a recommendation from the 2009 HRP SRP review. During the one-day meeting, each of the HRP Elements and Projects presented the changes they made to the HRP Integrated Research Plan (IRP Rev. B) over the last year, and what their top three areas of integration are between other HRP Elements/Projects. The Chair (+1) SRP spent sufficient time addressing the panel charge, either as a group or in a separate closed session, and the Chair (+1) SRP and the HRP presenters and observers, in most cases, had sufficient time to discuss during and after the presentations. The SRP made a final debriefing to the HRP Program Scientist, Dr. John B. Charles, prior to the close of the meeting on December 7, 2010. Overall, the Chair (+1) SRP concluded that most of the HRP Elements/Projects did a commendable job during the past year in addressing integration across the HRP scientific disciplines with the available resources. The Chair (+1) SRP agreed that the idea of integration between HRP Elements/Projects is noble, but believes all parties involved should have the same definition of integration, in order to be successful. The Chair (+1) SRP also believes that a key to successful integration is communication among the HRP Elements/Projects which may present a challenge. The Chair (+1) SRP recommends that the HRP have a workshop on program integration (with HRP Element

  10. Family Medicine Department Chairs' Opinions Regarding Scope of Practice.

    Science.gov (United States)

    Peterson, Lars E; Blackburn, Brenna; Phillips, Robert L; Mainous, Arch G

    2015-12-01

    Family physicians are trained broadly to provide the majority of health care across multiple settings; however, their scope of practice has narrowed. Department chairs' role modeling of a broad scope of practice may set the tone for faculty and trainees. In 2013, the authors surveyed family medicine department chairs about their scope of practice, personal and department characteristics, and attitudes and beliefs about scope of practice and role modeling. They used descriptive statistics and bivariate analyses to test for associations between scope of practice, personal and department characteristics, and attitudes and beliefs. They created a Scope of Practice Index by summing the number of services each respondent provided to compare scope of practice across chairs. Of 146 chairs, 88 responded (60.3% response rate); 85 were included in the final analysis. Sixty-five (77.4%) respondents were male; 73 (86.9%) were 51 years or older. Respondents spent a mean of 19.7% of their time in direct patient care and had a mean Scope of Practice Index of 11.9. Fifty-three (62.4%) disagreed that the scope of practice of family medicine was too broad for practicing physicians to keep up in all areas, and 56 (65.9%) believed that faculty should role model the full scope of practice to learners. Responses generally did not vary by respondents' personal scope of practice. Family medicine department chairs believe that role modeling a broad scope of practice increases students' interest in family medicine and encourages residency graduates to provide a wide range of services.

  11. Emotional Intelligence and Burnout in Academic Radiation Oncology Chairs.

    Science.gov (United States)

    Holliday, Emma B; Bonner, James A; Formenti, Silvia C; Hahn, Stephen M; Kalnicki, Shalom; Liu, Fei-Fei; Movsas, Benjamin; Fuller, Clifton D; Thomas, Charles R

    The importance of emotional intelligence (EI) in physicians has attracted attention as researchers begin to focus on the relationship of EI to retention, promotion, and productivity among academic physicians. However, to date, no formal evaluation of EI has been conducted among current department chairs. The objectives of this study were to assess the EI of current chairs of academic radiation oncology departments and to correlate EI with a self-reported assessment of burnout.The authors invited 95 chairs of academic radiation oncology departments to participate in a survey, approved by an institutional review board, consisting of the Trait Emotional Intelligence Questionnaire Short Form (TEIQue-SF) and the abbreviated Maslach Burnout Inventory (a-MBI). TEIQue-SF scores were evaluated for correlation with respondents' demographics and self-reported burnout scores on the a-MBI. Sixty chairs responded to the survey, for a response rate of 63.2%. The median (interquartile range) TEIQue-SF for the responding cohort was 172 (155-182) out of a maximum possible score of 210. The a-MBI emotional exhaustion and depersonalization subscores were low, with median (interquartile range) scores of 4 (2.25-6.75) and 1 (0-2.75) out of maximum possible scores of 18 and 30, respectively. Higher TEIQue-SF global scores were weakly correlated with decreased burnout. The study results show that academic radiation oncology chairs had a high EI and low rates of self-reported burnout. EI may be of increasing importance with respect to recruitment and retention of academic medical leaders.

  12. Cross-Reactive Sensor Array for Metal Ion Sensing Based on Fluorescent SAMs

    NARCIS (Netherlands)

    Basabe Desmonts, M.L.; van der Baan, Frederieke; Zimmerman, R.S.; Reinhoudt, David; Crego Calama, Mercedes

    2007-01-01

    Fluorescent self assembled monolayers (SAMs) on glass were previouslydeveloped in our group as new sensing materials for metal ions. These fluorescent SAMs arecomprised by fluorophores and small molecules sequentially deposited on a monolayer onglass. The preorganization provided by the surface

  13. ISO19770-1:2012 SAM process guidance

    CERN Document Server

    Canavan, Rory

    2012-01-01

    The pocket guide offers a concise summary of the principles of software asset management as conveyed by ISO 19770-1: 2012, and provides advice and guidance on how to kick-start your own SAM programme - something the Standard alone doesn't offer.

  14. Sam Karlin and multi-locus population genetics.

    Science.gov (United States)

    Feldman, Marcus W

    2009-06-01

    Between 1967 and 1982, Sam Karlin made fundamental contributions to many areas of deterministic population genetic theory. This remembrance focuses on his work in multi-locus population genetics, primarily on the interaction between genotypic selection and the rate of recombination.

  15. Social Activity Method (SAM): A Fractal Language for Mathematics

    Science.gov (United States)

    Dowling, Paul

    2013-01-01

    In this paper I shall present and develop my organisational language, "social activity method" (SAM), and illustrate some of its applications. I shall introduce a new scheme for "modes of recontextualisation" that enables the analysis of the ways in which one activity--which might be school mathematics or social research or any…

  16. 77 FR 50493 - Sam Rayburn Dam Project Power Rate

    Science.gov (United States)

    2012-08-21

    .... Procedures for Public Participation in Power and Transmission Rate Adjustments and Extensions of the Power... transmission facilities, which consist of 1,380 miles of high-voltage transmission lines, 25 substations, and 46 microwave and VHF radio sites. Costs associated ] with the Sam Rayburn and Robert D. Willis Dams...

  17. Social accounting matrices. The development and application of SAMs at the local level

    OpenAIRE

    van Leeuwen, E.S.; Nijkamp, P.

    2009-01-01

    This contribution aims to highlight the importance of Social Accounting Matrices (SAMs) for the study of regional-economic interactions. After a conceptual review of SAMs, the attention is focused on the empirical meaning of SAMs for economic impact assessment. The potential of SAMs is illustrated by an extensive pedagogical treatment of this tool on the basis of several town-hinterland interactions in 5 different European countries.

  18. Does a dynamic chair increase office workers' movements? - Results from a combined laboratory and field study.

    Science.gov (United States)

    Grooten, Wilhelmus J A; Äng, Björn O; Hagströmer, Maria; Conradsson, David; Nero, Håkan; Franzén, Erika

    2017-04-01

    Dynamic chairs have the potential to facilitate movements that could counteract health problems associated with sedentary office work. This study aimed to evaluate whether a dynamic chair can increase movements during desk-based office work. Fifteen healthy subjects performed desk-based office work using a dynamic office chair and compared to three other conditions in a movement laboratory. In a field study, the dynamic office chair was studied during three working days using accelerometry. Equivocal results showed that the dynamic chair increased upper body and chair movements as compared to the conventional chair, but lesser movements were found compared to standing. No differences were found between the conditions in the field study. A dynamic chair may facilitate movements in static desk-based office tasks, but the results were not consistent for all outcome measures. Validation of measuring protocols for assessing movements during desk-based office work is warranted. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Adsorption kinetic investigations of phthalocyanine derivatives self assembled monolayers (SAMs) on gold: Temperature influence on the SAM formation process and quality

    OpenAIRE

    Liličenko, Nadežda

    2015-01-01

    The ordered nano-structured surfaces, like self-assembled monolayers (SAMs) are of a great scientific interest, due to the low cost, simplicity, and versatility of this method. SAMs found numerous of applications in molecular electronics, biochemistry and optical devices. Phthalocyanine (Pc) complexes are of particular interest for the SAM preparation. These molecules exhibit fascinating physical properties and are chemically and thermally stable. Moreover their complex stru...

  20. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Posture chair for cardiac or pulmonary treatment... SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture chair for cardiac or pulmonary treatment. (a) Identification. A posture chair for cardiac or pulmonary...

  1. Effects of using dynamic office chairs on posture and EMG in standardized office tasks

    NARCIS (Netherlands)

    Ellegast, R.; Hamburger, R.; Keller, K.; Krause, F.; Groenesteijn, L.; Vink, P.; Berger, H.

    2007-01-01

    In the paper a measuring system for the comparative posture and EMG analysis of office chairs is presented. With the system four specific dynamic office chairs that promote dynamic sitting and therefore aim to prevent musculoskeletal disorders (MSD), were analyzed in comparison to a reference chair

  2. UNESCO Chair of Museology and World Heritage 1994 – 2002

    Directory of Open Access Journals (Sweden)

    Jan Dolák

    2016-03-01

    Full Text Available The UNESCO Chair on Museology and World Heritage was established at the Masaryk University in Brno in 1994. It commenced its activities in full in 1996 and Vinos Sofka (1928-2016, appointed in March 1995, became the first chairholder. The Chair was focused on the UNESCO transition project that dealt with the documentation of the totalitarian and postcolonial past of many countries in the former Soviet bloc, Latin America and other parts of the world. It was supported by the General conference of UNESCO resolution on Heritage, museum and museology for social, cultural and environmental transition (Transition project in October 1995 and the Czech Ministry of Education. The institution obtained a good reputation abroad while it remained somewhat controversial at home and it was eventually joined with the UNESCO International Summer School of Museology. In 2002, Vinoš Sofka left Brno and Jan Dolák become the new chairholder.

  3. Musical Chairs: An Innovative Teaching and Learning Method

    Science.gov (United States)

    Kuo, Ya-Hui

    2010-01-01

    How teaching and learning takes place in classrooms can be easily seen by the way classrooms are set up: Students' desks and chairs are arranged in rolls while teachers' desks are up front. Yet, why must teachers be the ones who lecture, why can't it be students? Would it be better or worse when teachers are the receivers and the students are the…

  4. Bourdieu, Department Chairs and the Reform of Science Education

    Science.gov (United States)

    Melville, Wayne; Hardy, Ian; Bartley, Anthony

    2011-11-01

    Using the insights of the French sociologist, Pierre Bourdieu, this article considers the role of the science department chair in the reform of school science education. Using Bourdieu's 'thinking tools' of 'field', 'habitus' and 'capital', we case study the work of two teachers who both actively pursue the teaching and learning of science as inquiry. One teacher, Dan, has been a department chair since 2000, and has actively encouraged his department to embrace science as inquiry. The other teacher, Leslie, worked for one year in Dan's department before being transferred to another school where science teaching continues to be more traditional. Our work suggests that there are three crucial considerations for chairs seeking to lead the reform of science teaching within their department. The first of these is the development of a reform-minded habitus, as this appears to be foundational to the capital that can be expended in the leadership of reform. The second is an understanding of how to wield power and position in the promotion of reform. The third is the capacity to operate simultaneously and strategically within, and across, two fields; the departmental field and the larger science education field. This involves downplaying administrative logics, and foregrounding more inquiry-focused logics as a vehicle to challenge traditional science-teaching dispositions-the latter being typically dominated by concerns about curriculum 'coverage'.

  5. Understanding the needs of department chairs in academic medicine.

    Science.gov (United States)

    Lieff, Susan; Banack, Jeannine Girard-Pearlman; Baker, Lindsay; Martimianakis, Maria Athina; Verma, Sarita; Whiteside, Catharine; Reeves, Scott

    2013-07-01

    The challenges for senior academic leadership in medicine are significant and becoming increasingly complex. Adapting to the rapidly changing environment of health care and medical education requires strong leadership and management skills. This article provides empirical evidence about the intricate needs of department chairs to provide insight into the design of support and development opportunities. In an exploratory case study, 21 of 25 (84%) department chairs within a faculty of medicine at a large Canadian university participated in semistructured interviews from December 2009 to February 2010. The authors conducted an inductive thematic analysis and identified a coding structure through an iterative process of relating and grouping of emerging themes. These participants were initially often insufficiently prepared for the demands of their roles. They identified a specific set of needs. They required cultural and structural awareness to navigate their hospital and university landscapes. A comprehensive network of support was necessary for eliciting advice and exchanging information, strategy, and emotional support. They identified a critical need for infrastructure growth and development. Finally, they stressed that they needed improvement in both effective interpersonal and influence skills in order to meet their mandate. Given the complexities and emotional burden of their role, it is necessary for chairs to have a range of supports and capabilities to succeed in their roles. Their leadership effectiveness can be enhanced by providing transitional processes and supports, development, and mentoring as well as facilitating the development of communities of peers.

  6. Automated One-Loop Calculations with GoSam

    CERN Document Server

    Cullen, Gavin; Heinrich, Gudrun; Luisoni, Gionata; Mastrolia, Pierpaolo; Ossola, Giovanni; Reiter, Thomas; Tramontano, Francesco

    2012-01-01

    We present the program package GoSam which is designed for the automated calculation of one-loop amplitudes for multi-particle processes in renormalisable quantum field theories. The amplitudes, which are generated in terms of Feynman diagrams, can be reduced using either D-dimensional integrand-level decomposition or tensor reduction. GoSam can be used to calculate one-loop QCD and/or electroweak corrections to Standard Model processes and offers the flexibility to link model files for theories Beyond the Standard Model. A standard interface to programs calculating real radiation is also implemented. We demonstrate the flexibility of the program by presenting examples of processes with up to six external legs attached to the loop.

  7. Technical Manual for the SAM Biomass Power Generation Model

    Energy Technology Data Exchange (ETDEWEB)

    Jorgenson, J.; Gilman, P.; Dobos, A.

    2011-09-01

    This technical manual provides context for the implementation of the biomass electric power generation performance model in the National Renewable Energy Laboratory's (NREL's) System Advisor Model (SAM). Additionally, the report details the engineering and scientific principles behind the underlying calculations in the model. The framework established in this manual is designed to give users a complete understanding of behind-the-scenes calculations and the results generated.

  8. Genome sequencing and annotation of Stenotrophomonas sp. SAM8.

    Science.gov (United States)

    Selim, Samy; Hassan, Sherif; Hagagy, Nashwa

    2015-12-01

    We report draft genome sequence of Stenotrophomonas sp. strain SAM8, isolated from environmental water. The draft genome size is 3,665,538 bp with a G + C content of 67.2% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA). The genome sequence can be accessed at DDBJ/EMBL/GenBank under the accession no. LDAV00000000.

  9. Simulated SAM A-scans on multilayer MEMS components

    DEFF Research Database (Denmark)

    Janting, Jakob; Petersen, Dirch Hjorth; Greisen, Christoffer

    2002-01-01

    A spreadsheet program for simulation of Scanning Acoustic Microscopy (SAM) A-scans on multilayer structures has been developed. Using this program, structure variations in samples can be analysed better. Further samples can be prepared to get optimal signal for enhanced failure and materials anal....... The calculation of N, the program interface, and simulated A-scans on MEMS test structures for a pressure sensor are presented. (C) 2002 Elsevier Science Ltd. All rights reserved....

  10. Genome sequencing and annotation of Stenotrophomonas sp. SAM8

    Directory of Open Access Journals (Sweden)

    Samy Selim

    2015-12-01

    Full Text Available We report draft genome sequence of Stenotrophomonas sp. strain SAM8, isolated from environmental water. The draft genome size is 3,665,538 bp with a G + C content of 67.2% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA. The genome sequence can be accessed at DDBJ/EMBL/GenBank under the accession no. LDAV00000000.

  11. A Conceptual Framework for Understanding the Working Relationship between School Principals and Vice-Principals

    Science.gov (United States)

    Wong, Ping-Man

    2009-01-01

    Vice-principals' role and their relationship with principals are of paramount importance in shaping the effectiveness of school management, particularly after the implementation of school-based management (SBM) worldwide. This paper reports primarily on prior studies on the vice-principalship and suggests a framework to help explain the different…

  12. Management and the Academic Vice President in the Christian, Liberal Arts College.

    Science.gov (United States)

    Oosting, Kenneth W.

    The role of nine academic vice presidents in managing Christian, liberal arts colleges was assessed, as part of research conducted at Christian or church-related liberal arts colleges that were identified as being well managed by one or more persons. Data collected on the academic vice presidents provided the following profile: the average age was…

  13. Developing Virtue and Rehabilitating Vice: Worries about Self-Cultivation and Self-Reform

    Science.gov (United States)

    Battaly, Heather

    2016-01-01

    Aristotelian virtue theorists have emphasized the role of the self in developing virtue and in rehabilitating vice. But this article argues that, as Aristotelians, we have placed too much emphasis on self-cultivation and self-reform. Self-cultivation is not required for developing virtue or vice. Nor will "sophia"-inspired self-reform…

  14. CE-SAM: a conversational interface for ISR mission support

    Science.gov (United States)

    Pizzocaro, Diego; Parizas, Christos; Preece, Alun; Braines, Dave; Mott, David; Bakdash, Jonathan Z.

    2013-05-01

    There is considerable interest in natural language conversational interfaces. These allow for complex user interactions with systems, such as fulfilling information requirements in dynamic environments, without requiring extensive training or a technical background (e.g. in formal query languages or schemas). To leverage the advantages of conversational interactions we propose CE-SAM (Controlled English Sensor Assignment to Missions), a system that guides users through refining and satisfying their information needs in the context of Intelligence, Surveillance, and Reconnaissance (ISR) operations. The rapidly-increasing availability of sensing assets and other information sources poses substantial challenges to effective ISR resource management. In a coalition context, the problem is even more complex, because assets may be "owned" by different partners. We show how CE-SAM allows a user to refine and relate their ISR information needs to pre-existing concepts in an ISR knowledge base, via conversational interaction implemented on a tablet device. The knowledge base is represented using Controlled English (CE) - a form of controlled natural language that is both human-readable and machine processable (i.e. can be used to implement automated reasoning). Users interact with the CE-SAM conversational interface using natural language, which the system converts to CE for feeding-back to the user for confirmation (e.g. to reduce misunderstanding). We show that this process not only allows users to access the assets that can support their mission needs, but also assists them in extending the CE knowledge base with new concepts.

  15. An investigation into the problems of easy chairs used by the arthritic and the elderly.

    Science.gov (United States)

    Munton, J S; Ellis, M I; Chamberlain, M A; Wright, V

    1981-08-01

    Groups such as the arthritic and the elderly are particularly susceptible to seating problems. An extensive questionnaire to determine the nature and extent seating difficulties was given to patients at rheumatology clinics and members of day centres for the elderly in Leeds. Forty-two per cent of subjects had some degree of difficulty in rising from their easy chair at home and of these 18% either experienced great difficulty or could not rise unaided. Only 13% had chairs designed to aid rising (e.g. high chair) and 40% of subjects thought their chair could be improved. Thirty-four per cent said that their easy chair caused them pain or discomfort. Information about subjects' body dimensions and their easy chair dimensions was also collected. Further research based on the survey results is planned in order to develop criteria for the design of easy chairs for the arthritic and the elderly.

  16. The SAMS: Smartphone Addiction Management System and verification.

    Science.gov (United States)

    Lee, Heyoung; Ahn, Heejune; Choi, Samwook; Choi, Wanbok

    2014-01-01

    While the popularity of smartphones has given enormous convenience to our lives, their pathological use has created a new mental health concern among the community. Hence, intensive research is being conducted on the etiology and treatment of the condition. However, the traditional clinical approach based surveys and interviews has serious limitations: health professionals cannot perform continual assessment and intervention for the affected group and the subjectivity of assessment is questionable. To cope with these limitations, a comprehensive ICT (Information and Communications Technology) system called SAMS (Smartphone Addiction Management System) is developed for objective assessment and intervention. The SAMS system consists of an Android smartphone application and a web application server. The SAMS client monitors the user's application usage together with GPS location and Internet access location, and transmits the data to the SAMS server. The SAMS server stores the usage data and performs key statistical data analysis and usage intervention according to the clinicians' decision. To verify the reliability and efficacy of the developed system, a comparison study with survey-based screening with the K-SAS (Korean Smartphone Addiction Scale) as well as self-field trials is performed. The comparison study is done using usage data from 14 users who are 19 to 50 year old adults that left at least 1 week usage logs and completed the survey questionnaires. The field trial fully verified the accuracy of the time, location, and Internet access information in the usage measurement and the reliability of the system operation over more than 2 weeks. The comparison study showed that daily use count has a strong correlation with K-SAS scores, whereas daily use times do not strongly correlate for potentially addicted users. The correlation coefficients of count and times with total K-SAS score are CC = 0.62 and CC =0.07, respectively, and the t-test analysis for the

  17. Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss.

    Directory of Open Access Journals (Sweden)

    Stéphane Richard

    2005-12-01

    Full Text Available The Src substrate associated in mitosis of 68 kDa (Sam68 is a KH-type RNA binding protein that has been shown to regulate several aspects of RNA metabolism; however, its physiologic role has remained elusive. Herein we report the generation of Sam68-null mice by homologous recombination. Aged Sam68-/- mice preserved their bone mass, in sharp contrast with 12-month-old wild-type littermates in which bone mass was decreased up to approximately 75%. In fact, the bone volume of the 12-month-old Sam68-/- mice was virtually indistinguishable from that of 4-month-old wild-type or Sam68-/- mice. Sam68-/- bone marrow stromal cells had a differentiation advantage for the osteogenic pathway. Moreover, the knockdown of Sam68 using short hairpin RNA in the embryonic mesenchymal multipotential progenitor C3H10T1/2 cells resulted in more pronounced expression of the mature osteoblast marker osteocalcin when differentiation was induced with bone morphogenetic protein-2. Cultures of mouse embryo fibroblasts generated from Sam68+/+ and Sam68-/- littermates were induced to differentiate into adipocytes with culture medium containing pioglitazone and the Sam68-/- mouse embryo fibroblasts shown to have impaired adipocyte differentiation. Furthermore, in vivo it was shown that sections of bone from 12-month-old Sam68-/- mice had few marrow adipocytes compared with their age-matched wild-type littermate controls, which exhibited fatty bone marrow. Our findings identify endogenous Sam68 as a positive regulator of adipocyte differentiation and a negative regulator of osteoblast differentiation, which is consistent with Sam68 being a modulator of bone marrow mesenchymal cell differentiation, and hence bone metabolism, in aged mice.

  18. The Effect of Holding a Research Chair on Scientists’ Impact

    Energy Technology Data Exchange (ETDEWEB)

    Mirnezami, S.R.; Beaudry, C.

    2016-07-01

    This paper examines the effect of holding Canada Research Chair (CRC) on a scientist’s number of citations as a measure of research impact, based on an econometric analysis with combined data on Quebec scientists’ funding and journal publication. Using Generalized Least Square (GLS) method for regression analysis, the results show that holding either tier-1 or tier- 2 of CRC significantly and positively results in conducting research with higher impact. This finding, however, does not necessarily imply that the others are the lesser scientists. (Author)

  19. Benchmarking Academic Anatomic Pathologists: The Association of Pathology Chairs Survey.

    Science.gov (United States)

    Ducatman, Barbara S; Parslow, Tristram

    2016-01-01

    The most common benchmarks for faculty productivity are derived from Medical Group Management Association (MGMA) or Vizient-AAMC Faculty Practice Solutions Center® (FPSC) databases. The Association of Pathology Chairs has also collected similar survey data for several years. We examined the Association of Pathology Chairs annual faculty productivity data and compared it with MGMA and FPSC data to understand the value, inherent flaws, and limitations of benchmarking data. We hypothesized that the variability in calculated faculty productivity is due to the type of practice model and clinical effort allocation. Data from the Association of Pathology Chairs survey on 629 surgical pathologists and/or anatomic pathologists from 51 programs were analyzed. From review of service assignments, we were able to assign each pathologist to a specific practice model: general anatomic pathologists/surgical pathologists, 1 or more subspecialties, or a hybrid of the 2 models. There were statistically significant differences among academic ranks and practice types. When we analyzed our data using each organization's methods, the median results for the anatomic pathologists/surgical pathologists general practice model compared to MGMA and FPSC results for anatomic and/or surgical pathology were quite close. Both MGMA and FPSC data exclude a significant proportion of academic pathologists with clinical duties. We used the more inclusive FPSC definition of clinical "full-time faculty" (0.60 clinical full-time equivalent and above). The correlation between clinical full-time equivalent effort allocation, annual days on service, and annual work relative value unit productivity was poor. This study demonstrates that effort allocations are variable across academic departments of pathology and do not correlate well with either work relative value unit effort or reported days on service. Although the Association of Pathology Chairs-reported median work relative value unit productivity

  20. Cardiovascular consequence of reclining vs. sitting beach-chair body position for induction of anesthesia

    DEFF Research Database (Denmark)

    Larsen, Soren L.; Lyngeraa, Tobias S.; Maschmann, Christian P.

    2014-01-01

    The sitting beach-chair position is regularly used for shoulder surgery and anesthesia may be induced in that position. We tested the hypothesis that the cardiovascular challenge induced by induction of anesthesia is attenuated if the patient is placed in a reclining beach-chair position....... Anesthesia was induced with propofol in the sitting beach-chair (n = 15) or with the beach-chair tilted backwards to a reclining beach-chair position (n = 15). The last group was stepwise tilted to the sitting beach-chair position prior to surgery. Hypotension was treated with ephedrine. Continuous...... ± 12 vs. 45 ± 15 % reduction from baseline, p = 0.04) and ScO2 (7 ± 6 vs. 1 ± 8% increase from baseline, p = 0.02) and received less ephedrine (mean: 4 vs. 13 mg, p = 0.048). The higher blood pressure and lower need of vasopressor following induction of anesthesia in the reclining compared...

  1. Congressmember Sam Farr: Five Decades of Public Service

    OpenAIRE

    Reti, Irene H.; Farr, Sam

    2017-01-01

    Congressmember Sam Farr (born July 4, 1941) represented California’s Central Coast in the United States House of Representatives for twenty-three years until his retirement from office in 2016.  Farr also served six years as a member of the Monterey County Board of Supervisors and twelve years in the California State Assembly. This oral history, a transcript of twenty-five hours of interviews conducted by Irene Reti, director of the UCSC Library’s Regional History Project, during the period i...

  2. Job satisfaction among chairs of surgery from Europe and North America.

    Science.gov (United States)

    Tschuor, Christoph; Raptis, Dimitri Aristotle; Morf, Manuela Christina; Staffelbach, Bruno; Manser, Tanja; Clavien, Pierre-Alain

    2014-11-01

    Strong evidence exists associating job satisfaction and risk of burnout with productivity, efficiency, and creativity in many organizations. However no data are available assessing chairs of surgery. This study assessed job satisfaction and risk for burnout of surgical chairs from Europe and North America and identified contributing factors. A survey among 650 chairs in surgery from 23 European and 2 North American countries was conducted in 2012. Satisfaction at work was analyzed using the validated Global Job Satisfaction (GJS) instrument and the abbreviated Maslach Burnout Inventory. Additional items targeting personal and environmental factors were included. The rate of chairs reached successfully was 86%, the overall response rate was 29% (188/650), with 1% female. Median age was 58 years. 11% of chairs were dissatisfied with work. Younger age and being fewer years in practice as a chair was associated with higher job satisfaction (P = .054 and P = .003). Surgical specialty with the greatest median GJS score was hepatopancreatobiliary, whereas vascular surgery scored lowest. Chairs desire to devote 20% more of their time on research. Clerical support as well as the ability to be innovative was suggested by 51% and 45%, respectively, to improve job satisfaction. Compared with Europeans, North American chairs were overall more satisfied and would recommend their job to their children. North American chairs seem to be more satisfied at work and at less risk for burnout than European chairs. The overall job satisfaction was greater among chairs compared with previously published reports of young, board-certified surgeons or residents (89% vs 87% and 66%, respectively). The superior satisfaction in chairs is strongest related to career achievements, innovation, and lifestyle. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Terry Clements named Council of Educators of Landscape Architecture first vice-president

    OpenAIRE

    Chadwick, Heather Riley

    2010-01-01

    Terry L. Clements, associate professor of landscape architecture in the School of Architecture + Design, College of Architecture and Urban Studies, was elected to serve as first vice-president of the Council of Educators of Landscape Architecture (CELA).

  4. 27 October 2014 - L. Pistelli Vice Minister at Foreign Affairs and International Cooperation, Italian Republic

    CERN Multimedia

    Guillaume, Jeanneret

    2014-01-01

    Mr Lapo Pistelli Vice Minister at Foreign Affairs and International Cooperation, Member of the Italian Parliament (Chamber of Deputies), Italian Republic, signing the Guest Book with CERN Director-General R. Heuer ; Physics Department Head L. Mapelli also present

  5. 2017-2018 Hospitality Expense Reports for Stephen McGurk, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    Description: Lunch - Development research issues. Date: 2017-05-30. Attendees: 2 (IDRC 1). Location: Nairobi, Kenya. Total: $12.10. Comments: 2017-2018 Hospitality Expense Reports for. Stephen McGurk, Vice-President, Program and Partnership Branch.

  6. Effects of dynamic office chairs on trunk kinematics, trunk extensor EMG and spinal shrinkage.

    Science.gov (United States)

    van Dieën, J H; de Looze, M P; Hermans, V

    2001-06-10

    Seated work has been shown to constitute a risk factor for low-back pain. This is attributed to the prolonged and monotonous low-level mechanical load imposed by a seated posture. To evaluate the potential health effects with respect to the low back of office chairs with a movable seat and back rest, trunk kinematics, erector spinae EMG, spinal shrinkage and local discomfort were assessed in 10 subjects performing simulated office work. On three separate occasions subjects performed a 3 h task consisting of word processing, computer-aided design and reading. Three chairs were used, one with a fixed seat and back rest and two dynamic chairs, one with a seat and back rest movable in a fixed ratio with respect to each other, and one with a freely movable seat and back rest. Spinal shrinkage measurements showed a larger stature gain when working on the two dynamic chairs as compared with working on the chair with fixed seat and back rest. Trunk kinematics and erector spinae EMG were strongly affected by the task performed but not by the chair type. The results imply that dynamic office chairs offer a potential advantage over fixed chairs, but the effects of the task on the indicators of trunk load investigated were more pronounced than the effects of the chair.

  7. A competency-based approach to recruiting, developing, and giving feedback to department chairs.

    Science.gov (United States)

    Palmer, Megan; Hoffmann-Longtin, Krista; Walvoord, Emily; Bogdewic, Stephen P; Dankoski, Mary E

    2015-04-01

    Academic health centers (AHCs) are under unprecedented pressure, making strong leadership during these challenging times critical. Department chairs have tremendous influence in their AHCs, yet data indicate that--despite outstanding academic credentials--they are often underprepared to take on these important leadership roles. The authors sought to improve the approach to recruiting, developing, and giving feedback to department chairs at their institution, the Indiana University School of Medicine (IUSM), by reorganizing these processes around six key leadership competencies: leadership and team development, performance and talent management, vision and strategic planning, emotional intelligence, communication skills, and commitment to the tripartite mission. Over a two-year period (2009-2011), IUSM faculty and administrators developed standardized recruitment procedures to assess potential chairs based on the six leadership domains, and searches are now streamlined through centralized staff support in the dean's office. Additionally, IUSM offers a chair development series to support learning around these leadership competencies and to meet the stated professional development needs of the chairs. Finally, chairs receive structured feedback regarding their leadership (among other considerations) through two different assessment instruments, IUSM's Department Chair 360° Leadership Survey and IUSM's Faculty Vitality Survey--both of which the dean reviews annually. Strategically attending to the way that chairs are selected, developed, and given feedback has tremendous potential to increase the success of chairs and, in turn, to constructively shape the culture of AHCs.

  8. Scientific production of Vice Chancellors for Research in Peruvian universities with a medical school.

    Science.gov (United States)

    Herrera-Añazco, Percy; Valenzuela-Rodríguez, Germán; Pacheco-Mendoza, Josmel; Málaga, Germán

    2017-10-19

    To determine the scientific production of Research Vice-chancellors at Peruvian universities that have medical schools, as well as their academic degrees as an indirect way to evaluate their suitability for the position they hold. We searched all Peruvian universities that register medical schools. Of these, the scientific production of the universities registered in SCOPUS was identified in September of the 2016. The scientific production of the vice chancellors of investigation of these faculties of medicine was determined through the search of its scientific publications registered in SCOPUS and those reported in the National Registry of Researchers in Science and Technology. Academic degrees were obtained from the database of the National Superintendence of Higher University Education. The sample included 28 research vice chancellors. Only 4/28 had any publications. The average number of articles published by the vice chancellors of research was 1.71, the number of citations 23.1 on average and the H index 0.64. Besides, 22 Vice-chancellors of research had the degree of doctor, four had the degree of bachelor and two the degree of master. The scientific production of research vice chancellors is poor. The required academic grade requirement for the position is not met in all cases. It is likely that, having no research experience, his leadership in directing a university's research policies may be questioned.

  9. American style or Turkish chair: the triumph of bodily comfort.

    Science.gov (United States)

    Çevik, Gülen

    2010-01-01

    This article investigates the reciprocal influence of Ottoman Turkish and American interiors in the development of seating furniture. Seating furniture is unique because it involves a direct and physical interaction between the piece of furniture and the body, while at the same time it is part of a public space where social interactions occur. I will argue that the interactions between the Ottoman Turks and Americans are reflected in the way these traditions modified their seating furniture as they sought to mediate cultural, political and social differences between them. The concept of bodily comfort will serve as a common thread in understanding the origin of the expression "American style" (Amerikan stili or Amerikan tarzı) in modern Turkish language, the "Turkish chairs" in Victorian America in the late nineteenth century and the English language use of words such as sofa, ottoman and divan.

  10. Airline Chair-rest Deconditioning: Induction of Immobilization Thromboemboli?

    Science.gov (United States)

    Greenleaf, J. E.; Rehrer, N. J.; Mohler, S. R.; Quach, D. T.; Evans, D. G.; Dalton, Bonnie P. (Technical Monitor)

    2002-01-01

    Air passenger miles will likely double by year 2020. The altered and restrictive environment in an airliner cabin can influence hematological homeostasis in passengers and crew. Flight-related deep various thromboemboli (DVT) have been associated with at least 577 deaths on 42 of 120 airlines from 1977 to 1984 (25 deaths/million departures), whereas many such cases go unreported. However, there are four major factors that could influence formation of possible flight-induced DVT: sleeping accomodations (via sitting immobilization), travelers' medical history (via tissue injury), cabin environmental factors (via lower partial pressure of oxygen and lower relative humidity), and the more encompassing chair-rest deconditioning (C-RD) syndrome. There is ample evidence that recent injury and surgery (especially in deconditioned hospitalized patients) facilitate thrombophlebitis and formation of DVT that may be exacerbated by the immobilization of prolonged air travel. In the healthy flying population immobilization factors associated with prolonged (> 5 hr) C-RID such as total body dehydration, hypovolemia and increased blood viscosity, and reduced various blood flow (pooling) in the legs may facilitate formation of DVT. However, data from at least four case-controlled epidemiological studies did not confirm a direct causative relationship between air travel and DART, but factors such as history of vascular thromboemboli, various insufficiency, chronic heart failure, obesity, immobile standing position, more than 3 pregnancies, infectious disease, long-distance travel, muscular trauma and violent physical effort were significantly more frequent in DVT patients than in controls. Thus, there is no clear, direct evidence yet that prolonged sitting in airliner seats, or prolonged experimental chair-rest- or bed- rest-deconditioning treatments cause deep various thromboemboli in healthy people.

  11. Airline chair-rest deconditioning: induction of immobilisation thromboemboli?

    Science.gov (United States)

    Greenleaf, John E.; Rehrer, Nancy J.; Mohler, Stanley R.; Quach, David T.; Evans, David G.

    2004-01-01

    Air passenger miles will likely double by year 2020. The altered and restrictive environment in an airliner cabin can influence haematological homeostasis in passengers and crew. Flight-related deep venous thromboemboli (DVT) have been associated with at least 577 deaths on 42 of 120 airlines from 1977 to 1984 (25 deaths/million departures), whereas many such cases go unreported. However, there are four major factors that could influence formation of possible flight-induced DVT: sleeping accommodations (via sitting immobilisation); travellers' medical history (via tissue injury); cabin environmental factors (via lower partial pressure of oxygen and lower relative humidity); and the more encompassing chair-rest deconditioning (C-RD) syndrome. There is ample evidence that recent injury and surgery (especially in deconditioned hospitalised patients) facilitate thrombophlebitis and formation of DVT that may be exacerbated by the immobilisation of prolonged air travel.In the healthy flying population, immobilisation factors associated with prolonged (>5 hours) C-RD such as total body dehydration, hypovolaemia and increased blood viscosity, and reduced venous blood flow (pooling) in the legs may facilitate formation of DVT. However, data from at least four case-controlled epidemiological studies did not confirm a direct causative relationship between air travel and DVT, but factors such as a history of vascular thromboemboli, venous insufficiency, chronic heart failure, obesity, immobile standing position, more than three pregnancies, infectious disease, long-distance travel, muscular trauma and violent physical effort were significantly more frequent in DVT patients than in controls. Thus, there is no clear, direct evidence yet that prolonged sitting in airliner seats, or prolonged experimental chair-rest or bed-rest deconditioning treatments cause DVT in healthy people.

  12. Report of the 10(th) Asia-Pacific Federation of Societies for Surgery of the Hand Congress (Organising Chair and Scientific Chair).

    Science.gov (United States)

    A, Roohi Sharifah; Abdullah, Shalimar

    2016-10-01

    A report on the 10(th) Asia-Pacific Federation of Societies for the Surgery of the Hand and 6(th) Asia-Pacific Federation of Societies for Hand Therapists is submitted detailing the numbers of attendees participating, papers presented and support received as well the some of the challenges faced and how best to overcome them from the local conference chair and scientific chair point of view.

  13. A newly developed floor chair placed on an office chair reduces lumbar muscle fatigue by cyclically changing its lumbar supporting shape

    OpenAIRE

    Matsuda, Tadamitsu; Koyama, Takayuki; Kurihara, Yasushi; Tagami, Miki; Kusumoto, Yasuaki; Nitta, Osamu

    2017-01-01

    [Purpose] This study investigated lumbar muscle fatigue before and after maintaining a seated position for one hour, lumbar and pelvic inclination angle change, in subjects with and without active lumber support. [Subjects and Methods] Fourteen healthy subjects randomized into two groups sat on a floor chair, placed on an office chair, that cyclically changed its lumbar supporting shape to provide active lumbar support (ALS) or no ALS for one hour. Before and after, we measured the frequency ...

  14. The History of the Austin College Building and Old Main at Sam Houston State University

    Science.gov (United States)

    Singer, Erin; Shields, Samantha

    2017-01-01

    Austin Hall and Old Main serve as the heart of what is now Sam Houston State University. The buildings' rich histories help one to understand how Sam Houston State University and its proud teacher education heritage came to be. To begin with Austin Hall's story, the University's original building has a unique and interesting tale that journeys…

  15. canada's “thousand talent program”i: how canada research chair ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2013-10-24

    Oct 24, 2013 ... richer explanation of brain circulation, using the case study of Chinese holders of Canada Research Chairs. (CRC). Canada suffered brain drain in the 1990s, in particular to the United States. The Canada. Research Chair Program (CRCP), launched in 2000 by the Government of Canada, signalled the ...

  16. 76 FR 20651 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2011-04-13

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of... Environmental Management Site-Specific Advisory Board Chairs (76 FR 17118). This notice announces the...-7711. Issued at Washington, DC, on April 8, 2011. LaTanya R. Butler, Acting Deputy Committee Management...

  17. The Community College Department Chair and Curriculum Leadership: Managing Learning and Learning to Manage

    Science.gov (United States)

    Sweeney, Kathleen Jennings

    2012-01-01

    Dwindling resources, the challenges of providing postsecondary remedial education, and an environment that emphasizes outcomes assessment are realities that confront the community college department chair. The role of the department chair is particularly challenging in the community college context due to accountability pressures, fiscal…

  18. Office task effects on comfort and body dynamics in five dynamic office chairs

    NARCIS (Netherlands)

    Groenesteijn, L.; Ellegast, R.P.; Keller, K.; Krause, F.; Berger, H.; Looze, M.P.de

    2012-01-01

    In the present study, we investigated the effect of office tasks on posture and movements in field settings, and the comfort rating for chair characteristics and correlation with type of task. The tasks studied were: computer work, telephoning, desk work and conversation. Postures, movements, chair

  19. The Body Language Behaviours of the Chairs of the Disputes According to the Disputants

    Science.gov (United States)

    Caliskan, Nihat

    2009-01-01

    The perception form of the body language behaviours of the session chairs by disputants affects the efficiency of the process. Therefore, it is important to determine the effects of the mimic, gesture, physical appearance and tonality and accent of the chairs on disputants. That research was conducted to clarify how the disputants perceive the…

  20. Evaluation the reliability and validity of students\\' satisfaction questionnaire from training chairs

    Directory of Open Access Journals (Sweden)

    Samira Ansari

    2017-09-01

    conclusion: according to this study's results, in investigating the validity and reliability indices of questoinnaire developed by the researcher was noted that this questionnaire have a proper validity and reliability to assess students' satisfaction from training chairs and can be used to assess any office and student chairs.

  1. Effectiveness of Ergonomic Chair against Musculoskeletal Disorders in Female Batik Workers of Sragen District

    Directory of Open Access Journals (Sweden)

    Sumardiyono Sumardiyono

    2014-08-01

    Full Text Available The majority of female batik workers uses non-ergonomic chairs (dingklik that pose risks of musculoskeletal disorders. This study aimed to design an ergonomic chair and evaluate its effectiveness in reducing musculoskeletal disorders among the workers. This is a quasi-experimental study (using one group pre and post-test design on 50 female batik workers selected by quota sampling. Musculoskeletal disorders were measured among the samples before and after the use of the designed ergonomic chair which they were asked to use for two months. T-test, ANCOVA, Wilcoxon test, McNemar test and Chi Square test were used for the analysis. The study found statistical significant differences of risk factor against musculoskeletal disorders among the workers before and after their use of the designed ergonomic chair (p=0.000; and of musculoskeletal disorders before and after using the ergonomic chair (p= 0,035. Body Mass Index (BMI was identified as a confounding factor, and statistical significant difference of musculoskeletal disorders were also found among the workers with 25 BMI even before and after using the ergonomic chair (p=0.033 and p=0.015 respectively. By ANCOVA statistical test, after controlling BMI, another statistical difference of musculoskeletal disorders was also identified before and after using the ergonomic chair (p=0.033. It is concluded that the designed ergonomic chair is effective to reduce the risk of musculoskeletal disorders.

  2. Academic Leaders in Alabama Community Colleges: Roles and Tasks of Department Chairs.

    Science.gov (United States)

    Palmer, A. Dale; Miller, Michael T.

    This document describes the findings from a survey conducted to compare the middle-level managers, department, and unit chairs and heads in Alabama's two-year colleges with those identified in the National Community College Chair Academy Survey of 1994. In particular, the study was designed to note differences or similarities between the national…

  3. Effects of differences in office chair controls, seat and backrest angle design in relation to tasks

    NARCIS (Netherlands)

    Groenesteijn, L.; Vink, P.; Looze, M. de; Krause, F.

    2009-01-01

    In this study the influence of chair characteristics on comfort, discomfort, adjustment time and seat interface pressure is investigated during VDU and non-VDU tasks: The two investigated office chairs, both designed according to European and Dutch standards are different regarding: 1) seat

  4. Development of an inexpensive, low attenuation styrofoam primate chair for use in a PET scanner.

    Science.gov (United States)

    Kortekaas, R; van Waarde, A; Maguire, R P; Leenders, K L; Elsinga, P H

    2004-04-01

    Pharmacokinetic modelling of radiotracers for positron emission tomography (PET) imaging of neuroreceptors can be performed with time-activity data for brain and blood. We aimed to develop an alternative to withdrawal of arterial blood samples for acquisition of a blood curve. A supportive primate chair was constructed out of styrofoam and fixed to the head portion of the bed of a PET scanner. A lightly anaesthetised rhesus monkey was positioned in the chair in a sitting position and injected with the radiotracer. The styrofoam chair provided sufficient support for the monkey. The presence of the chair in the PET scanner caused negligible attenuation of radiation, allowing simultaneous acquisition of dynamic data from the subject's brain and heart. We conclude that a styrofoam primate chair is an ideal tool to measure blood and brain data from a rhesus monkey with PET. Invasiveness to the animal is reduced, as well as experimenter time.

  5. Political Leadership in Parliament: The Role of Select Committee Chairs in the UK House of Commons

    Directory of Open Access Journals (Sweden)

    Alexandra Kelso

    2016-06-01

    Full Text Available Concepts of political leadership have been applied sparingly to parliaments, and not at all to the study of House of Commons select committees in the UK Parliament, where analysis has largely focused on their institutional capacity to scrutinise government and hold it to account. Yet examining these committees through a political leadership lens illuminates the complex role of committee chairs, a role which was significantly reshaped in 2010 with a shift to election of chairs by the whole House. This article analyses select committee chairs through the lens of political leadership, and draws on a series of interviews with chairs in order to delineate the nature of the political leadership they perform. It argues that, as chairs are now increasingly important parliamentary and policy actors, our understanding of them is significantly advanced by conceptualising their role as one of parliamentary political leadership, and that this in turn enriches our analytical toolkit when it comes to the study of parliaments.

  6. Radical SAM-Mediated Methylation of Ribosomal RNA

    Science.gov (United States)

    Stojkovic, Vanja; Fujimori, Danica Galonić

    2015-01-01

    Post-transcriptional modifications of RNA play an important role in a wide range of biological processes. In ribosomal RNA (rRNA), methylation of nucleotide bases is the predominant modification. In recent years, methylation of adenosine 2503 (A2503) in bacterial 23S rRNA has attracted significant attention due to both the unusual regioselectivity of the methyl group incorporation, as well as the pathophysiological roles of the resultant methylations. Specifically, A2503 is methylated at the C2 and C8 positions of the adenine ring, and the introduced modifications have a profound impact on translational fidelity and antibiotic resistance, respectively. These modifications are performed by RlmN and Cfr, two members, of the recently discovered class of radical S-adenosylmethionine (radical SAM) methylsynthases. Here, we present several methods that can be used to evaluate the activity of these enzymes, under both in vivo and in vitro conditions. PMID:26253978

  7. S.A.M., the Italian Martian Simulation Chamber

    Science.gov (United States)

    Galletta, G.; Ferri, F.; Fanti, G.; D'Alessandro, M.; Bertoloni, G.; Pavarin, D.; Bettanini, C.; Cozza, P.; Pretto, P.; Bianchini, G.; Debei, S.

    2006-12-01

    The Martian Environment Simulator (SAM “Simulatore di Ambiente Marziano”) is a interdisciplinary project of Astrobiology done at University of Padua. The research is aimed to the study of the survival of the microorganisms exposed to the “extreme” planetary environment. The facility has been designed in order to simulate Mars’ environmental conditions in terms of atmospheric pressure, temperature cycles and UV radiation dose. The bacterial cells, contained into dedicated capsules, will be exposed to thermal cycles simulating diurnal and seasonal Martian cycles. The metabolism of the different biological samples will be analysed at different phases of the experiment, to study their survival and eventual activity of protein synthesis (mortality, mutations and capability of DNA reparing). We describe the experimental facility and provide the perspectives of the biological experiments we will perform in order to provide hints on the possibility of life on Mars either autochthonous or imported from Earth.

  8. Cooperation between Magnesium and Metabolite Controls Collapse of the SAM-I Riboswitch.

    Science.gov (United States)

    Roy, Susmita; Onuchic, José N; Sanbonmatsu, Karissa Y

    2017-07-25

    The S-adenosylmethionine (SAM)-I riboswitch is a noncoding RNA that regulates the transcription termination process in response to metabolite (SAM) binding. The aptamer portion of the riboswitch may adopt an open or closed state depending on the presence of metabolite. Although the transition between the open and closed states is critical for the switching process, its atomistic details are not well understood. Using atomistic simulations, we calculate the effect of SAM and magnesium ions on the folding free energy landscape of the SAM-I riboswitch. These molecular simulation results are consistent with our previous wetlab experiments and aid in interpreting the SHAPE probing measurements. Here, molecular dynamics simulations explicitly identify target RNA motifs sensitive to magnesium ions and SAM. In the simulations, we observe that, whereas the metabolite mostly stabilizes the P1 and P3 helices, magnesium serves an important role in stabilizing a pseudoknot interaction between the P2 and P4 helices, even at high metabolite concentrations. The pseudoknot stabilization by magnesium, in combination with P1 stabilization by SAM, explains the requirement of both SAM and magnesium to form the fully collapsed metabolite-bound closed state of the SAM-I riboswitch. In the absence of SAM, frequent open-to-closed conformational transitions of the pseudoknot occur, akin to breathing. These pseudoknot fluctuations disrupt the binding site by facilitating fluctuations in the 5'-end of helix P1. Magnesium biases the landscape toward a collapsed state (preorganization) by coordinating pseudoknot and 5'-P1 fluctuations. The cooperation between SAM and magnesium in stabilizing important tertiary interactions elucidates their functional significance in transcription regulation. Published by Elsevier Inc.

  9. Systematic biochemical characterization of the SAM domains in Eph receptor family from Mus Musculus.

    Science.gov (United States)

    Wang, Yue; Li, Qingxia; Zheng, Yunhua; Li, Gang; Liu, Wei

    2016-05-13

    The Eph receptor family is the largest subfamily of receptor tyrosine kinases and well-known for their pivotal roles in axon guidance, synaptogenesis, artery/venous differentiation and tumorigenesis, etc. Activation of the Eph receptor needs multimerization of the receptors. The intracellular C-terminal SAM domain of Eph receptor was reported to mediate self-association of Eph receptors via the homo SAM-SAM interaction. In this study, we systematically expressed and purified the SAM domain proteins of all fourteen Eph receptors of Mus musculus in Escherichia coli. The FPLC (fast protein liquid chromatography) results showed the recombinant SAM domains were highly homogeneous. Using CD (circular dichroism) spectrometry, we found that the secondary structure of all the SAM domains was typically alpha helical folded and remarkably similar. The thermo-stability tests showed that they were quite stable in solution. SEC-MALS (size exclusion chromatography coupled with multiple angle light scattering) results illustrated 200 μM Eph SAM domains behaved as good monomers in the size-exclusion chromatography. More importantly, DLS (dynamic light scattering) results revealed the overwhelming majority of SAM domains was not multimerized in solution either at 200 μM or 2000 μM protein concentration, which indicating the SAM domain alone was not sufficient to mediate the polymerization of Eph receptor. In summary, our studies provided the systematic biochemical characterizations of the Eph receptor SAM domains and implied their roles in Eph receptor mediated signaling pathways. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Teleconnection stationarity, variability and trends of the Southern Annular Mode (SAM) during the last millennium

    Science.gov (United States)

    Dätwyler, Christoph; Neukom, Raphael; Abram, Nerilie J.; Gallant, Ailie J. E.; Grosjean, Martin; Jacques-Coper, Martín; Karoly, David J.; Villalba, Ricardo

    2017-11-01

    The Southern Annular Mode (SAM) is the leading mode of atmospheric interannual variability in the Southern Hemisphere (SH) extra-tropics. Here, we assess the stationarity of SAM spatial correlations with instrumental and paleoclimate proxy data for the past millennium. The instrumental period shows that temporal non-stationarities in SAM teleconnections are not consistent across the SH land areas. This suggests that the influence of the SAM index is modulated by regional effects. However, within key-regions with good proxy data coverage (South America, Tasmania, New Zealand), teleconnections are mostly stationary over the instrumental period. Using different stationarity criteria for proxy record selection, we provide new austral summer and annual mean SAM index reconstructions over the last millennium. Our summer SAM reconstructions are very robust to changes in proxy record selection and the selection of the calibration period, particularly on the multi-decadal timescale. In contrast, the weaker performance and lower agreement in the annual mean SAM reconstructions point towards changing teleconnection patterns that may be particularly important outside the summer months. Our results clearly portend that the temporal stationarity of the proxy-climate relationships should be taken into account in the design of comprehensive regional and hemispherical climate reconstructions. The summer SAM reconstructions show no significant relationship to solar, greenhouse gas and volcanic forcing, with the exception of an extremely strong negative anomaly following the AD 1257 Samalas eruption. Furthermore, reconstructed pre-industrial summer SAM trends are very similar to trends obtained by model control simulations. We find that recent trends in the summer SAM lie outside the 5-95% range of pre-industrial natural variability.

  11. Social activity method (SAM): A fractal language for mathematics

    Science.gov (United States)

    Dowling, Paul

    2013-09-01

    In this paper I shall present and develop my organisational language, social activity method (SAM), and illustrate some of its applications. I shall introduce a new scheme for modes of recontextualisation that enables the analysis of the ways in which one activity - which might be school mathematics or social research or any empirically observed regularity of practice - recontextualises the practice of another and I shall also present, deploy, and develop an existing scheme - domains of action - in an analysis of school mathematics examination papers and in the structuring of what I refer to as the esoteric domain. This domain is here conceived as a hybrid domain of, first, linguistic and extralinguistic resources that are unambiguously mathematical in terms of both expression and content and, second, pedagogic theory - often tacit - that enables the mathematical gaze onto other practices and so recontextualises them. A second and more general theme that runs through the paper is the claim that there is nothing that is beyond semiosis, that there is nothing to which we have direct access, unmediated by interpretation. This state of affairs has implications for mathematics education. Specifically, insofar as an individual's mathematical semiotic system is under continuous development - the curriculum never being graspable all at once - understanding - as a stable semiotic moment - of any aspect or object of mathematics is always localised to the individual and is at best transient, and the sequencing of such moments may well also be more individualised than consistent in some correspondence with the sequencing of the curriculum. This being the case, a concentration on understanding as a goal may well serve to inhibit the pragmatic acquisition and deployment of mathematical technologies, which should be the principal aim of mathematics teaching and learning. The paper is primarily concerned with mathematics education. SAM, however, is a language that is available for

  12. Economic Analysis Case Studies of Battery Energy Storage with SAM

    Energy Technology Data Exchange (ETDEWEB)

    DiOrio, Nicholas [National Renewable Energy Lab. (NREL), Golden, CO (United States); Dobos, Aron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Janzou, Steven [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    Interest in energy storage has continued to increase as states like California have introduced mandates and subsidies to spur adoption. This energy storage includes customer sited behind-the-meter storage coupled with photovoltaics (PV). This paper presents case study results from California and Tennessee, which were performed to assess the economic benefit of customer-installed systems. Different dispatch strategies, including manual scheduling and automated peak-shaving were explored to determine ideal ways to use the storage system to increase the system value and mitigate demand charges. Incentives, complex electric tariffs, and site specific load and PV data were used to perform detailed analysis. The analysis was performed using the free, publically available System Advisor Model (SAM) tool. We find that installation of photovoltaics with a lithium-ion battery system priced at $300/kWh in Los Angeles under a high demand charge utility rate structure and dispatched using perfect day-ahead forecasting yields a positive net-present value, while all other scenarios cost the customer more than the savings accrued. Different dispatch strategies, including manual scheduling and automated peak-shaving were explored to determine ideal ways to use the storage system to increase the system value and mitigate demand charges. Incentives, complex electric tariffs, and site specific load and PV data were used to perform detailed analysis. The analysis was performed using the free, publically available System Advisor Model (SAM) tool. We find that installation of photovoltaics with a lithium-ion battery system priced at $300/kWh in Los Angeles under a high demand charge utility rate structure and dispatched using perfect day-ahead forecasting yields a positive net-present value, while all other scenarios cost the customer more than the savings accrued.

  13. DOE Chair of Excellence Professorship in Environmental Disciplines

    Energy Technology Data Exchange (ETDEWEB)

    Shoou-Yuh Chang

    2013-01-31

    The United States (US) nuclear weapons program during the Cold War left a legacy of radioactive, hazardous, chemical wastes and facilities that may seriously harm the environment and people even today. Widespread public concern about the environmental pollution has created an extraordinary demand for the treatment and disposal of wastes in a manner to protect the public health and safety. The pollution abatement and environmental protection require an understanding of technical, regulatory, economic, permitting, institutional, and public policy issues. Scientists and engineers have a major role in this national effort to clean our environment, especially in developing alternative solutions and evaluation criteria and designing the necessary facilities to implement the solutions. The objective of the DOE Chair of Excellence project is to develop a high quality educational and research program in environmental engineering at North Carolina A&T State University (A&T). This project aims to increase the number of graduate and undergraduate students trained in environmental areas while developing a faculty concentrated in environmental education and research. Although A&T had a well developed environmental program prior to the Massie Chair grant, A&T's goal is to become a model of excellence in environmental engineering through the program's support. The program will provide a catalyst to enhance collaboration of faculty and students among various engineering departments to work together in a focus research area. The collaboration will be expanded to other programs at A&T. The past research focus areas include: hazardous and radioactive waste treatment and disposal fate and transport of hazardous chemicals in the environment innovative technologies for hazardous waste site remediation pollution prevention Starting from 2005, the new research focus was in the improvement of accuracy for radioactive contaminant transport models by ensemble based data assimilation

  14. Aquinas on the Dangers of Natural Virtue and the Control of Natural Vice

    Directory of Open Access Journals (Sweden)

    Marie I. George

    2013-11-01

    Full Text Available I investigate Aquinas’s position that natural virtue can pose dangers to living a moral life, dangers that include natural virtue’s inflexibility to circumstance, the opposing vices it may breed if blindly followed, and its aptitude for deceiving people into thinking they are genuinely virtuous. I also consider whether Aquinas regards these problems as remediable given that he sees natural virtue and natural vice as instances of nature being determined to one. He maintains that we can overcome the moral pitfalls that natural virtue and natural vice pose, though perfect mastery is not possible without divine intervention, insofar as our bodily disposition is not directly subject to reason.

  15. Sam68 exerts separable effects on cell cycle progression and apoptosis

    Directory of Open Access Journals (Sweden)

    Resnick Ross J

    2004-01-01

    Full Text Available Abstract Background The RNA-binding protein Sam68 has been implicated in a number of cellular processes, including transcription, RNA splicing and export, translation, signal transduction, cell cycle progression and replication of the human immunodeficiency virus and poliovirus. However, the precise impact it has on essential cellular functions remains largely obscure. Results In this report we show that conditional overexpression of Sam68 in fibroblasts results in both cell cycle arrest and apoptosis. Arrest in G1 phase of the cell cycle is associated with decreased levels of cyclins D1 and E RNA and protein, resulting in dramatically reduced Rb phosphorylation. Interestingly, cell cycle arrest does not require the specific RNA binding ability of Sam68. In marked contrast, induction of apoptosis by Sam68 absolutely requires a fully-functional RNA binding domain. Moreover, the anti-cancer agent trichostatin A potentiates Sam68-driven apoptosis. Conclusions For the first time we have shown that Sam68, an RNA binding protein with multiple apparent functions, exerts functionally separable effects on cell proliferation and survival, dependent on its ability to bind specifically to RNA. These findings shed new light on the ability of signal transducing RNA binding proteins to influence essential cell function. Moreover, the ability of a class of anti-cancer therapeutics to modulate its ability to promote apoptosis suggests that Sam68 status may impact some cancer treatments.

  16. SU-C-19A-05: Treatment Chairs for Modern Radiation Therapy Treatments

    Energy Technology Data Exchange (ETDEWEB)

    Court, L; Fullen, D; Tharp, K; Palmer, J; Ungchusri, G; Reyes, L; Tong, T; Nguyen, S; Phillips, T; Balter, P [UT MD Anderson Cancer Center, Houston, TX (United States)

    2014-06-15

    Purpose: Treating patients in a seated position has potential advantages including improved comfort, increased lung volume, and reduced respiratory motion. We compared chair designs for head and neck, thoracic and breast patients for use with either IGRT linacs or a proposed low-cost fixed horizontal beam-line machine. Methods: Three treatment chairs were designed and constructed. Two of the chairs are based on a massage-chair, with the patient angled slightly forwards and knee rests used to minimize intra-fraction slouch. The third chair design is more conventional; the patient is angled backwards, with indexed positioning devices and the ability to attach thermoplastic masks. Patient geometries, including PTV location and patient sizes, were extracted from 137 CTs of past patients were used to model the probability of collision between the patient and the linac for various seated positions. All chairs were designed around the weight limits for couches on our linacs. At the time of writing we have just received IRB approval for imaging studies to evaluate comfort, and intra- and interfraction reproducibility. Results: The geometric analysis showed that head and neck patients and thoracic patients could be treated without collision. However, there is very limited space between the patient and the treatment/imaging devices, so careful design of the chair is essential. The position of the treatment target and extended arm positioning means that this is a particular concern for thoracic and breast patients. This was demonstrated for one of the prototype chairs designed for breast treatment where the arm holders would collide with the kV detector. The extra clearance of a dedicated fixed-beam linac would overcome these difficulties. Intra- and inter-fraction reproducibility results will be presented at the meeting. Conclusion: To take advantage of the clinical advantages of seated treatments, appropriate treatment chairs are needed. A dedicate fixed-beam linac may

  17. Demographic and Personal Characteristics of Male and Female Chairs in Academic Psychiatry.

    Science.gov (United States)

    Doyle, Marley; Pederson, Aderonke; Meltzer-Brody, Samantha

    2016-06-01

    Despite the strong representation of female psychiatrists in residency and early-career positions, the number of female faculty sharply decreases in tenured or executive leadership positions. Why there exists a marked change in representation at the level of senior leadership within academic psychiatry is unclear. The authors investigated the causative factors contributing to this observation and gathered information about the personal characteristics of women in executive leadership roles. The authors surveyed psychiatry chairs at academic institutions. They identified all female chairs and randomly selected a group of male chairs to serve as a control group. The survey assessed perceived barriers, strengths, and weaknesses and differences in demographics and leadership styles between female and male chairs. Ten percent of psychiatry chairs were female. Male chairs were more likely than female chairs to head large departments (p = 0.02, confidence interval (CI) -17.1-69.1) and had a higher H-index (p = 0.001, CI 6.6-37.2). Female chairs were more likely than male chairs to perceive barriers in their career development (p = 0.01, CI 0.7-2.2), citing little or no mentorship (p = 0.04), gender discrimination (p = 0.0001), and family obligations (p = 0.001) more often. Academic institutions must incorporate programs to decrease barriers and work to achieve equitable representation of women in upper-level leadership positions. Moreover, academic medicine must evolve to cultivate a family-friendly environment that successfully supports both genders.

  18. 76 FR 774 - Folding Metal Tables and Chairs From the People's Republic of China: Notice of Extension of Time...

    Science.gov (United States)

    2011-01-06

    ... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China: Notice... chairs from the People's Republic of China (``PRC''). See Folding Metal Tables and Chairs: Initiation of... March 20, 2011. However, because March 20, 2011, falls on a weekend, the actual due date will be the...

  19. Low Profile, High Impact: Four Case Studies of High School Department Chairs Whose Transactions "Transform" Teachers and Administrators.

    Science.gov (United States)

    Wettersten, Jill A.

    This paper explores the leadership strategies of four exemplary high school department chairs. It develops a model based on social-exchange theory to show how chairs, as middle managers, must satisfy the expectations of both teachers and administrators. Data were derived from a case study of department chairs identified as exemplary in four…

  20. 77 FR 39680 - Folding Metal Tables and Chairs From the People's Republic of China: Final Results of Antidumping...

    Science.gov (United States)

    2012-07-05

    ... Metal Tables and Chairs From the People's Republic of China: Final Results of Antidumping Duty... review of the antidumping duty order on folding metal tables and chairs from the People's Republic of... ``Final Results of Review'' section below. \\1\\ See Folding Metal Tables and Chairs From the People's...

  1. 76 FR 72903 - Folding Metal Tables and Chairs From the People's Republic of China: Notice of Correction to the...

    Science.gov (United States)

    2011-11-28

    ... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China: Notice... the antidumping duty order on folding metal tables and chairs from the People's Republic of China...'').'' \\2\\ \\1\\ See Folding Metal Tables and Chairs From the People's Republic of China: Final Results of...

  2. Automation of One-Loop Calculations with GoSam: Present Status and Future Outlook

    CERN Document Server

    Cullen, Gavin; Heinrich, Gudrun; Luisoni, Gionata; Mastrolia, Pierpaolo; Ossola, Giovanni; Reiter, Thomas; Tramontano, Francesco

    2011-01-01

    In this presentation, we describe the GoSam (Golem/Samurai) framework for the automated computation of multi-particle scattering amplitudes at the one-loop level. The amplitudes are generated analytically in terms of Feynman diagrams, and can be evaluated using either D-dimensional integrand reduction or tensor decomposition. GoSam can be used to compute one-loop corrections to Standard Model (QCD and EW) processes, and it is ready to link generic model files for theories Beyond SM. We show the main features of GoSam through its application to several examples of different complexity.

  3. [Development and application on rehabilitation chair of preventing low back pain].

    Science.gov (United States)

    Wang, Hong

    2013-07-01

    This paper discusses the necessary factors keeping normal spine curve and body pressure uniform distribution in sitting posture based on analysis sitting posture of low back pain and long time sitting persons. The purpose is to correct the sitting posture and prevention low back pain by changing the curves of the chair and material. 16 patients with low back pain were equally divided into research group and control group. The patients in research group accepted the rehabilitation chair, and other patients in control group accepted the chair same to before. JOA score were used as effect measures in both groups. The differences were statistically significant (P low back pain.

  4. Three essays on the economics of science policy: The impact of funding, collaboration and research chairs

    Science.gov (United States)

    Mirnezami, Seyed Reza

    This thesis studies the determinants that influence the number of citations, the effect of having a research collaboration with top-funded scientists on scientific productivity, and the effect of holding a research chair on scientific productivity. Based on a review study by Bornmann and Daniel (2008), one can argue that non-scientific factors determining the decision to cite do not significantly alter the role of citation as a measure of research impact. Assuming that the number of citations is a good measure for research impact and, in turn, for a certain kind of quality, we showed that the number of articles and the visibility of a researcher, the impact factor of the journal, the size of the research team, and the institutional setting of the university are the important determinants of citation counts. However, we have found that there is no significant effect of public funding and gender in most of the domains examined. The point that funding amount is not a significant determinant of citation counts does not necessarily contradict the positive effect of funding on scientific productivity. We also developed a theoretical model and proposed some hypotheses about the effect of collaboration with top-funded scientists on scientific productivity. We then validated the hypotheses with empirical analysis and showed that such collaboration has a positive effect on scientific productivity. This significant effect may exist through different channels: transfer of tacit knowledge, more scientific publications, economy of scale in knowledge production because of better research equipment, and expanded research network. The results also verified the positive effect of funding, the positive effect of networking (measured by number of co-authors), the inverted U-shaped effect of age, and the fewer number of publications by women compared to men. Finally, we made a distinction between different attributes of research chairs and their effect on scientific productivity. One

  5. Perspectives of UK Vice-Chancellors on Leading Universities in a Knowledge-Based Economy

    Science.gov (United States)

    Bosetti, Lynn; Walker, Keith

    2010-01-01

    This paper draws upon the experiences and perceptions of ten university vice-chancellors in the United Kingdom on the challenges they face in providing leadership and strategic direction for their institutions into the twenty-first century. The paper reveals the perceptions and spoken words of these leaders as they identify the key challenges…

  6. The conversion of spring wheat into winter wheat and vice versa ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 35; Issue 2. The conversion of spring wheat into winter wheat and vice versa: false claim or Lamarckian inheritance? Xiuju Li Yongsheng Liu. Mini-review Volume 35 Issue 2 June 2010 pp 321-325 ...

  7. Dr Jung Hyun KIM Vice Minister for Education, Science and Technology MEST Republic of Korea

    CERN Multimedia

    Jean-Claude Gadmer

    2010-01-01

    He learnt about CERN's LHC computing grid project from Frédéric Hemmer, head of the information technology department. In addition, the vice-minister toured the ATLAS visitor centre, the CMS control centre, the ALICE experiment's exhibition and control room, and he met Korean scientists at CERN.

  8. 2017-2018 Hospitality Expense Reports for Stephen McGurk, Vice ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    Description: Dinner with development research partners. Date: 2017-05-16. Attendees: 6 (IDRC 3). Location: Yangon, Myanmar. Total: $68.52. Comments: 2017-2018 Hospitality Expense Reports for. Stephen McGurk, Vice-President, Program and Partnership Branch.

  9. Time scales: from Nabla calculus to Delta calculus and vice versa via duality

    OpenAIRE

    Caputo, M. Cristina

    2009-01-01

    In this note we show how one can obtain results from the nabla calculus from results on the delta calculus and vice versa via a duality argument. We provide applications of the main results to the calculus of variations on time scales.

  10. The Academic Role of the Vice President for Health Sciences: Can a Walrus Become a Unicorn?

    Science.gov (United States)

    Pellegrino, Edmund D.

    1975-01-01

    The Vice President for Health Sciences is a term used for the chief administrative officer of a multi-unit health science component of a university. This essay reviews this job, and the transformation it has undergone in the past. (Editor/PG)

  11. Am I Their Cup of Tea? Vice-Principals' Perception of Suitability for Principalship

    Science.gov (United States)

    Kwan, Paula

    2013-01-01

    This paper attempts to address the principal shortage issue from the concept of fit perceived by job applicants. It links vice-principals' perception of suitability for principalship to their conception of how well they can match with the selection criteria set out by school hiring bodies. Based on evidence collected from aspiring principals in…

  12. Effects of Vice-Principals' Psychological Empowerment on Job Satisfaction and Burnout

    Science.gov (United States)

    Schermuly, Carsten C.; Schermuly, Rene A.; Meyer, Bertolt

    2011-01-01

    Purpose: This paper aims to investigate the relationship between psychological empowerment, job satisfaction, and burnout among vice-principals (VPs) in primary schools. Design/methodology/approach: A total of 103 VPs at 103 different primary schools in Germany were surveyed with a questionnaire that assessed the four dimensions of psychological…

  13. Vestibulopathy and age effects on head stability during chair rise.

    Science.gov (United States)

    McGibbon, C A; Krebs, D E; Scarborough, D M

    2001-01-01

    It is unknown how vestibular dysfunction and age differentially affect balance control during functional activities. The objective of this study was to gain insight into the effects of age and vestibulopathy on head control when rising from a chair. Head relative to trunk (head-on-trunk) sagittal plane angular and linear control strategies were studied in patients with bilateral vestibular hypofunction (BVH) and in healthy subjects aged 30-80 years. A two-way analysis of variance was used to compare head-on-trunk kinematics by age (young vs elderly) and diagnosis (healthy vs BVH) at the time of liftoff from the seat. Angular control strategies differed with age but not diagnosis: young (healthy and BVH) subjects stabilized head rotations in space while elderly (healthy and BVH) subjects stabilized head rotations on the trunk. In contrast, linear control strategies differed by diagnosis but not age: BVH subjects (young and old) allowed a greater rate of head-on-trunk translation while healthy subjects (young and old) inhibited such translations. Young BVH subjects stabilized head-in-space rotations (as did young healthy subjects) without a functioning vestibular system, suggesting cervicocollic reflex and/or other sensory compensation for vestibular loss. Elderly BVH subjects stabilized head rotation with respect to the trunk, as did healthy elders, but did not stabilize head-on-trunk translations, suggesting a reliance on passive mechanical responses of the neck to sense head movements. We conclude that compensation strategies used by patients with vestibulopathy are age-dependent and appear to be more tractable in the younger BVH patient.

  14. A Qualitative Analysis of the Leadership Style of a Vice-Chancellor in a Private University in Malaysia

    Directory of Open Access Journals (Sweden)

    Mabel Tan

    2015-03-01

    Full Text Available This study used Bolman and Deal’s framework to examine the leadership frames of a vice-chancellor in a private university in Malaysia. Qualitative methods comprised interviews with the vice-chancellor and six of his staff reporting directly to him, document analysis, and observations. Atlas.ti was used to code the leadership frames. Content analysis revealed that the vice-chancellor exhibited three frames, showing a multi-frame leadership style. It reflects the vice-chancellor implements an effective leadership style and a high level of cognitive ability, which is important for the organizational effectiveness.

  15. Medical Devices; Exemption From Premarket Notification; Class II Devices; Electric Positioning Chair. Final order.

    Science.gov (United States)

    2015-11-20

    The Food and Drug Administration (FDA or the Agency) is publishing an order granting a petition requesting exemption from premarket notification requirements for electric positioning chair devices. An electric positioning chair is a device with a motorized positioning control that is intended for medical purposes and that can be adjusted to various positions. These devices are used to provide stability for patients with athetosis (involuntary spasms) and to alter postural positions. This order exempts electric positioning chairs, class II devices, from premarket notification, subject to certain conditions for exemption. This exemption from premarket notification, subject to these conditions (and the limitations in the physical medicine devices limitations of exemptions from premarket notification section of the device regulations), is immediately in effect for electric positioning chairs. FDA is publishing this order in accordance with the exemption from class II premarket notification section of the Federal Food, Drug, and Cosmetic Act (the FD&C Act).

  16. Trapezius Muscle Activity in using Ordinary and Ergonomically Designed Dentistry Chairs

    Directory of Open Access Journals (Sweden)

    O Haddad

    2012-03-01

    Full Text Available Background: Most dentists complain of musculoskeletal disorders which can be caused by prolonged static posture, lack of suitable rest and other physical and psychological problems. Objective: We evaluated a chair with a new ergonomic design which incorporated forward leaning chest and arm supports. Methods: The chair was evaluated in the laboratory during task simulation and EMG analysis on 12 students and subjectively assessed by 30 professional dentists using an 18-item questionnaire. EMG activity of right and left trapezius muscles for 12 male students with no musculoskeletal disorders was measured while simulating common tasks like working on the teeth of the lower jaw. Results: Normalized EMG data showed significant reduction (p<0.05 in all EMG recordings of the trapezius muscle. Dentists also unanimously preferred the ergonomically designed chair. Conclusion: Such ergonomically designed chairs should be introduced as early as possible in student training before bad postural habits are acquired.

  17. Must, valge + hall : Sam Wagstaffi ja Robert Mapplethorpe'i portree / Madis Palm

    Index Scriptorium Estoniae

    Palm, Madis

    2008-01-01

    Dokumentaalfilm "Black, White & Gray: Sam Wagstaff and Robert Mapplethorpe" : autor ja režissöör James Crump : Ameerika Ühendriigid 2007. Filmi näidati filminädala "Art in America" raames Tallinnas

  18. Smoking-Attributable Mortality, Morbidity, and Economic Costs (SAMMEC) - Smoking-Attributable Mortality (SAM)

    Data.gov (United States)

    U.S. Department of Health & Human Services — 2005-2009. SAMMEC - Smoking-Attributable Mortality, Morbidity, and Economic Costs. Smoking-attributable mortality (SAM) is the number of deaths caused by cigarette...

  19. Stability of binary SAMs formed by omega-acid and alcohol functionalized thiol mixtures.

    Science.gov (United States)

    Tielens, Frederik; Humblot, Vincent; Pradier, Claire-Marie; Calatayud, Monica; Illas, Francesc

    2009-09-01

    A simple model is presented to describe the mixing process of acid- and alcohol-terminated thiol self-assembled monolayers (SAMs) on Au(111). It was found that the low-concentration acid-terminated SAMs are enriched in acid thiol compared with the original solution from which the SAM is made. Due to the relatively strong interaction between acid and alcohol head groups, homogeneously mixed SAMs showing alcohol/acid pairs are preferred when the acid-terminated thiol fraction in solution is below or equal to 50%. This particular behavior affecting the mixing process is explained using atomistic first-principle thermodynamics. The calculated phase diagram has been discussed and interpreted with the help of XPS.

  20. Bringing a Chemical Laboratory Named Sam to Mars on the 2011 Curiosity Rover

    Science.gov (United States)

    Mahaffy, P. R.; Bleacher, L.; Jones, A.; Atreya, S. K.; Manning, H. L.; Cabane, M.; Webster, C. R.; Sam Team

    2010-12-01

    Introduction: An important goal of upcoming missions to Mars is to understand if life could have developed there. The task of the Sample Analysis at Mars (SAM) suite of instruments [1] and the other Curiosity investigations [2] is to move us steadily toward that goal with an assessment of the habitability of our neighboring planet through a series of chemical and geological measurements. SAM is designed to search for organic compounds and inorganic volatiles and measure isotope ratios. Other instruments on Curiosity will provide elemental analysis and identify minerals. SAM will analyze both atmospheric samples and gases evolved from powdered rocks that may have formed billions of years ago with Curiosity providing access to interesting sites scouted by orbiting cameras and spectrometers. SAM Instrument Suite: SAM’s instruments are a Quadrupole Mass Spectrometer (QMS), a 6-column Gas Chromatograph (GC), and a 2-channel Tunable Laser Spectrometer (TLS). SAM can identify organic compounds in Mars rocks to sub-ppb sensitivity and secure precise isotope ratios for C, H, and O in carbon dioxide and water and measure trace levels of methane and its carbon 13 isotope. The SAM gas processing system consists of valves, heaters, pressure sensors, gas scrubbers and getters, traps, and gas tanks used for calibration or combustion experiments [2]. A variety of calibrant compounds interior and exterior to SAM will allow the science and engineering teams to assess SAM’s performance. SAM has been calibrated and tested in a Mars-like environment. Keeping Educators and the Public Informed: The Education and Public Outreach (EPO) goals of the SAM team are to make this complex chemical laboratory and its data widely available to educators, students, and the public. Formal education activities include developing templates for professional development workshops for educators to teach them about SAM and Curiosity, incorporating data into Mars Student Data Teams, and writing articles

  1. Quality Improvement Practices in Academic Emergency Medicine: Perspectives from the Chairs

    OpenAIRE

    DelliFraine, Jami L.; Langabeer, James II; King, Brent

    2010-01-01

    Objective: To assess academic emergency medicine (EM) chairs’ perceptions of quality improvement (QI) training programs. Methods: A voluntary anonymous 20 item survey was distributed to a sample of academic chairs of EM through the Association of Academic Chairs of Emergency Medicine. Data was collected to assess the percentage of academic emergency physicians who had received QI training, the type of training they received, their perception of the impact of this training on behavior...

  2. Nouvelle initiative des chaires de recherche Canada-Afrique du Sud ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    8 déc. 2016 ... L'Initiative de partenariats trilatéraux des chaires de recherche Canada-Afrique du Sud a pour objectif d'investir dans le développement de la ... recherche du Canada ou chaire de recherche industrielle) et un chercheur principal provenant d'un autre pays d'Afrique visé par un accord bilatéral avec la NRF, ...

  3. Mr Gary Nairn MP, Chair of the Standing Committee on Science and Innovation, Australia

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Photos 01,04,06,07: Mr Gary Nairn MP, Chair of the Standing Committee on Science and Innovation, Australia,visiting the silicon test laboratory, April 2003. Photos 02,03: From left to right: Mr Gary Nairn MP, Chair of the Standing Committee on Science and Innovation, Australia,visiting the silicon test laboratory with Prof. Steinar Stapnes, Physicist in the ATLAS experiment, April 2003. Photos 02,09: Mrs Kerrye Nairn, Australia,visiting the silicon test laboratory, April 2003

  4. Association of Medical School Pediatric Department Chairs Principles of Lifelong Learning in Pediatric Medicine.

    Science.gov (United States)

    Opipari, Valerie P; Daniels, Stephen R; Wilmott, Robert W; Jacobs, Richard F

    2016-11-01

    Pediatric general and subspecialty care requires continuous effort to maintain knowledge and competencies in clinical practice. Equally important are efforts by investigators and educators to maintain knowledge and competencies in the conduct of research and training. The Association of Medical School Pediatric Department Chairs initiated a survey in July 2015 to define principles of lifelong learning in pediatric medicine and determine the approaches and strategies used by chairs to assess knowledge and competence across the care, research, and teaching missions. A total of 101 of 142 chairs (71%) completed the survey. Six of 7 proposed principles were endorsed by 84% to 96% of Association of Medical School Pediatric Department Chairs members. The focus areas included individual accountability, individually relevant activities, use of evidence-based guidelines/national standards, gaining cognitive expertise, learning as a continuous effort, affordability, and focus on individual understanding. The chairs endorsed a requirement for evidence of lifelong learning, competence, and compliance by all faculty members in clinical (n = 89 [88%]), research (n = 63 [62%]), and educational (n = 85 [84%]) practice. The survey identified the strategies to assess lifelong learning and faculty competence and compliance in clinical, research, and educational roles. Across missions, chairs endorsed an expectation for individual responsibility supplemented by formal evaluation practices and institutional and regulatory office oversight. While chairs endorsed an important role for the American Board of Pediatrics in assessing and verifying lifelong learning, knowledge, and competence in general and specialty certification, most (n = 91 [90%]) endorsed a need to revise current board requirements to better emphasize closing gaps in knowledge and using approaches that are evidence-based. This study provides the perspectives of pediatric department chairs on principles

  5. Political Leadership in Parliament: The Role of Select Committee Chairs in the UK House of Commons

    OpenAIRE

    Alexandra Kelso

    2016-01-01

    Concepts of political leadership have been applied sparingly to parliaments, and not at all to the study of House of Commons select committees in the UK Parliament, where analysis has largely focused on their institutional capacity to scrutinise government and hold it to account. Yet examining these committees through a political leadership lens illuminates the complex role of committee chairs, a role which was significantly reshaped in 2010 with a shift to election of chairs by the whole Hou...

  6. Advancing Women's Health and Women's Leadership With Endowed Chairs in Women's Health.

    Science.gov (United States)

    Carnes, Molly; Johnson, Paula; Klein, Wendy; Jenkins, Marjorie; Bairey Merz, C Noel

    2017-02-01

    Gender-based bias and conflation of gender and status are root causes of disparities in women's health care and the slow advancement of women to leadership in academic medicine. More than a quarter of women physicians train in internal medicine and its subspecialties, and women physicians almost exclusively constitute the women's health focus within internal medicine. Thus, internal medicine has considerable opportunity to develop women leaders in academic medicine and promote women's health equity.To probe whether holding an endowed chair-which confers status-in women's health may be an effective way to advance women leaders in academic medicine and women's health, the authors explored the current status of endowed chairs in women's health in internal medicine. They found that the number of these endowed chairs in North America increased from 7 in 2013 to 19 in 2015, and all were held by women. The perceptions of incumbents and other women's health leaders supported the premise that an endowed chair in women's health would increase women's leadership, the institutional stature of women's health, and activities in women's health research, education, and clinical care.Going forward, it will be important to explore why not all recipients perceived that the endowed chair enhanced their own academic leadership, whether providing women's health leaders with fundraising expertise fosters future success in increasing the number of women's health endowed chairs, and how the conflation of gender and status play out (e.g., salary differences between endowed chairs) as the number of endowed chairs in women's health increases.

  7. Identification of trans-acting factors regulating SamDC expression in Oryza sativa

    Energy Technology Data Exchange (ETDEWEB)

    Basu, Supratim, E-mail: supratim_genetics@yahoo.co.in [Department of Crop Soil and Environmental Sciences, University of Arkansas, Fayetteville, AR 72701 (United States); Division of Plant Biology, Bose Institute, Kolkata (India); Roychoudhury, Aryadeep [Post Graduate Department of Biotechnology, St. Xavier' s College (Autonomous), 30, Mother Teresa Sarani, Kolkata - 700016, West Bengal (India); Sengupta, Dibyendu N. [Division of Plant Biology, Bose Institute, Kolkata (India)

    2014-03-07

    Highlights: • Identification of cis elements responsible for SamDC expression by in silico analysis. • qPCR analysis of SamDC expression to abiotic and biotic stress treatments. • Detection of SamDC regulators using identified cis-elements as probe by EMSA. • Southwestern Blot analysis to predict the size of the trans-acting factors. - Abstract: Abiotic stress affects the growth and productivity of crop plants; to cope with the adverse environmental conditions, plants have developed efficient defense machinery comprising of antioxidants like phenolics and flavonoids, and osmolytes like polyamines. SamDC is a key enzyme in the polyamine biosynthesis pathway in plants. In our present communication we have done in silico analysis of the promoter region of SamDC to look for the presence of different cis-regulatory elements contributing to its expression. Based on the presence of different cis-regulatory elements we completed comparative analysis of SamDC gene expression in rice lamina of IR-29 and Nonabokra by qPCR in response to the abiotic stress treatments of salinity, drought, cold and the biotic stress treatments of ABA and light. Additionally, to explore the role of the cis-regulatory elements in regulating the expression of SamDC gene in plants we comparatively analyzed the binding of rice nuclear proteins prepared from IR-29 and Nonabokra undergoing various stress treatments. The intensity of the complex formed was low and inducible in IR-29 in contrast to Nonabokra. Southwestern blot analysis helped in predicting the size of the trans-acting factors binding to these cis-elements. To our knowledge this is the first report on the comprehensive analysis of SamDC gene expression in rice and identification of the trans-acting factors regulating its expression.

  8. The Combustion Experiment on the Sample Analysis at Mars (SAM) Instrument Suite on the Curiosity Rover

    Science.gov (United States)

    Stern, J. C.; Malespin, C. A.; Eigenbrode, J. L.; Graham, H. V.; Archer, P. D., Jr.; Brunner, A. E.; Freissinet, C.; Franz, H. B.; Fuentes, J.; Glavin, D. P.; hide

    2014-01-01

    The combustion experiment on the Sample Analysis at Mars (SAM) suite on Curiosity will heat a sample of Mars regolith in the presence of oxygen and measure composition of the evolved gases using quadrupole mass spectrometry (QMS) and tunable laser spectrometry (TLS). QMS will enable detection of combustion products such as CO, CO2, NO, and other oxidized species, while TLS will enable precise measurements of the abundance and carbon isotopic composition (delta(sup 13)C) of the evolved CO2 and hydrogen isotopic composition (deltaD) of H2O. SAM will perform a two-step combustion to isolate combustible materials below approx.550 C and above approx.550 C. The combustion experiment on SAM, if properly designed and executed, has the potential to answer multiple questions regarding the origins of volatiles seen thus far in SAM evolved gas analysis (EGA) on Mars. Constraints imposed by SAM and MSL time and power resources, as well as SAM consumables (oxygen gas), will limit the number of SAM combustion experiments, so it is imperative to design an experiment targeting the most pressing science questions. Low temperature combustion experiments will primarily target the quantification of carbon (and nitrogen) contributed by SAM wet chemistry reagants MTBSTFA (N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide) and DMF (Dimethylformamide), which have been identified in the background of blank and sample runs and may adsorb to the sample while the cup is in the Sample Manipulation System (SMS). In addition, differences between the sample and "blank" may yield information regarding abundance and delta(sup 13)C of bulk (both organic and inorganic) martian carbon. High temperature combustion experiments primarily aim to detect refractory organic matter, if present in Cumberland fines, as well as address the question of quantification and deltaD value of water evolution associated with hydroxyl hydrogen in clay minerals.

  9. Benchmark Simulation of Natural Circulation Cooling System with Salt Working Fluid Using SAM

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, K. K.; Scarlat, R. O.; Hu, R.

    2017-09-03

    Liquid salt-cooled reactors, such as the Fluoride Salt-Cooled High-Temperature Reactor (FHR), offer passive decay heat removal through natural circulation using Direct Reactor Auxiliary Cooling System (DRACS) loops. The behavior of such systems should be well-understood through performance analysis. The advanced system thermal-hydraulics tool System Analysis Module (SAM) from Argonne National Laboratory has been selected for this purpose. The work presented here is part of a larger study in which SAM modeling capabilities are being enhanced for the system analyses of FHR or Molten Salt Reactors (MSR). Liquid salt thermophysical properties have been implemented in SAM, as well as properties of Dowtherm A, which is used as a simulant fluid for scaled experiments, for future code validation studies. Additional physics modules to represent phenomena specific to salt-cooled reactors, such as freezing of coolant, are being implemented in SAM. This study presents a useful first benchmark for the applicability of SAM to liquid salt-cooled reactors: it provides steady-state and transient comparisons for a salt reactor system. A RELAP5-3D model of the Mark-1 Pebble-Bed FHR (Mk1 PB-FHR), and in particular its DRACS loop for emergency heat removal, provides steady state and transient results for flow rates and temperatures in the system that are used here for code-to-code comparison with SAM. The transient studied is a loss of forced circulation with SCRAM event. To the knowledge of the authors, this is the first application of SAM to FHR or any other molten salt reactors. While building these models in SAM, any gaps in the code’s capability to simulate such systems are identified and addressed immediately, or listed as future improvements to the code.

  10. Pengaruh Kompetensi Pegawai terhadap Peningkatan Kualitas Pelayanan Publik di Kantor Pusat Universitas Sam Ratulangi Ma

    OpenAIRE

    Tulusan, Femmy M; RARES, Joyce J; Lumi, Djefry

    2015-01-01

    Sam Ratulangi University as one of the major universities are very concerned will be given public service employees, to the competence of the employees is a problem that is considered by the leadership, because without a good employee competence given the public service will not be maximized. The research methodology used is that while the survey is descriptive analytical method. The target population in this study is that there are employees in the Central Office and the University of Sam Ra...

  11. Annual Energy Savings and Thermal Comfort of Autonomously Heated and Cooled Office Chairs

    Energy Technology Data Exchange (ETDEWEB)

    Carmichael, Scott [National Renewable Energy Lab. (NREL), Golden, CO (United States); Booten, Chuck [National Renewable Energy Lab. (NREL), Golden, CO (United States); Robertson, Joseph [National Renewable Energy Lab. (NREL), Golden, CO (United States); Chin, Justin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Christensen, Dane [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Jacquelyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Arent, Doug [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-07-01

    Energy use in offices buildings is largely driven by air conditioning demands. But the optimal temperature is not the same for all building occupants, leading to the infamous thermostat war. And many occupants have independently overcome building comfort weaknesses with their own space heaters or fans. NREL tested is a customized office chair that automatically heats and cools the occupant along the seat and chair back according to the occupants' personal preferences. This product is shown to deliver markedly better comfort at room temperatures well above typical office cooling setpoints. Experimental subjects reported satisfaction in these elevated air temperatures, partly because the chair's cooling effect was tuned to their own individual needs. Simulation of the chair in office buildings around the U.S. shows that energy can be saved everywhere, with impacts varying due to the climate. Total building HVAC energy savings exceeded 10% in hot-dry climate zones. Due to high product cost, simple payback for the chair we studied is beyond the expected chair life. We then understood the need to establish cost-performance targets for comfort delivery packages. NREL derived several hypothetical energy/cost/comfort targets for personal comfort product systems. In some climate regions around the U.S., these show the potential for office building HVAC energy savings in excess of 20%. This report documents this research, providing an overview of the research team's methods and results while also identifying areas for future research building upon the findings.

  12. Fabrication and Surface Properties of Composite Films of SAM/Pt/ZnO/SiO 2

    KAUST Repository

    Yao, Ke Xin

    2008-12-16

    Through synthetic architecture and functionalization with self-assembled monolayers (SAMs), complex nanocomposite films of SAM/Pt/ZnO/SiO2 have been facilely prepared in this work. The nanostructured films are highly uniform and porous, showing a wide range of tunable wettabilities from superhydrophilicity to superhydrophobicity (water contact angles: 0° to 170°). Our approach offers synthetic flexibility in controlling film architecture, surface topography, coating texture, crystallite size, and chemical composition of modifiers (e.g., SAMs derived from alkanethiols). For example, wettability properties of the nanocomposite films can be finely tuned with both inorganic phase (i.e., ZnO/SiO2 and Pt/ZnO/SiO2) and organic phase (i.e., SAMs on Pt/ZnO/SiO2). Due to the presence of catalytic components Pt/ZnO within the nanocomposites, surface reactions of the organic modifiers can further take place at room temperature and elevated temperatures, which provides a means for SAM formation and elimination. Because the Pt/ZnO forms an excellent pair of metal-semiconductors for photocatalysis, the anchored SAMs can also be modified or depleted by UV irradiation (i.e., the films possess self-cleaning ability). Potential applications of these nanocomposite films have been addressed. Our durability tests also confirm that the films are thermally stable and structurally robust in modification- regeneration cycles. © 2008 American Chemical Society.

  13. Effect of Furniture Weight on Carrying, Lifting, and Turning of Chairs and Desks among Elementary School Children.

    Science.gov (United States)

    Purwaningrum, Lu'lu'; Funatsu, Kyotaro; Xiong, Jinghong; Rosyidi, Cucuk Nur; Muraki, Satoshi

    2015-01-01

    Rearranging furniture in elementary school classrooms encourages classroom activities. In elementary schools in Indonesia and some other developing countries, usually only one style of furniture is used for all children, and the furniture is heavy and oversized for younger children. This affects their ability to carry it. The objective of this study is to investigate the effects of elementary school furniture weight and children's age on performance of three carrying tasks (carrying a chair, lifting and turning a chair on a desk, and carrying both a chair and a desk together), from the ergonomics point of view. A total of 42 schoolchildren (ages 6-9; 17 Indonesian, 25 Japanese) participated in this study. Two types of Japanese chairs (Chair A and B, weight: 3.2 kg and 3.9 kg), one type of Indonesian chair (Chair C, weight: 5.0 kg), and two types of desks (height: 58 cm and 68 cm) were used. Indonesian chairs took significantly longer time to carry than the two Japanese chairs, and there was a significant negative relationship between age and task time for Chairs B and C, but not Chair A. Success rates for lifting and turning the chair declined as age decreased and chair weight increased, but were not significantly influenced by desk height. Success rates for carrying a chair and desk together significantly decreased with heavier furniture. Children aged six showed an extremely low success rate in almost all conditions. In conclusion, children's ability to carry furniture is affected by their age and furniture characteristics, especially weight. In order to encourage classroom activities in elementary school, school furniture should be of appropriate weight. Supervision for younger children is required during classroom furniture arrangement.

  14. Eighties' Film Noir: An Analysis of the Use of the "Double" in "Miami Vice's" Second and Third Seasons.

    Science.gov (United States)

    Matviko, John W.

    A comparison of the current television series "Miami Vice" with the "film noir" genre of American movies from the forties and fifties reveals many similar elements, such as visual style, mood, theme, and sensibility. "Miami Vice" is set in a large city whose art deco architecture provides an ironic contrast to noir's…

  15. Community College Vice Presidents for Institutional Advancement: Role Expectations, Fundraising Responsibilities, Professional Relationships, and Commitment to the Institution

    Science.gov (United States)

    Ciampa, Donna Lynn

    2009-01-01

    This study examined how the role expectations, responsibilities toward fundraising, and professional relationships by the vice president of institutional advancement influenced commitment to the institution. A qualitative analysis was conducted across the mid-Atlantic region by interviewing community college vice presidents of institutional…

  16. Vehicle Infrastructure Cash-Flow Estimation--VICE 2.0; Clean Cities, Energy Efficiency & Renewable Energy (EERE)

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, G.

    2015-04-02

    This presentation discusses the differences between the original Vehicle and Infrastructure Cash-Flow Evaluation (VICE) Model and the revamped version, VICE 2.0. The enhanced tool can now help assess projects to acquire vehicles and infrastructure, or to acquire vehicles only.

  17. SAM-Like Evolved Gas Analyses of Phyllosilicate Minerals and Applications to SAM Analyses of the Sheepbed Mudstone, Gale Crater, Mars

    Science.gov (United States)

    McAdam, A. C.; Franz, H. B.; Mahaffy, P. R.; Eigenbrode, J. L.; Stern, J. C.; Brunner, B.; Sutter, B.; Archer, P. D.; Ming , D. W.; Morris, R. V.; hide

    2014-01-01

    While in Yellowknife Bay, the Mars Science Laboratory Curiosity rover collected two drilled samples, John Klein (hereafter "JK") and Cumberland ("CB"), from the Sheepbed mudstone, as well as a scooped sample from the Rocknest aeolian bedform ("RN"). These samples were sieved by Curiosity's sample processing system and then several subsamples of these materials were delivered to the Sample Analysis at Mars (SAM) instrument suite and the CheMin X-ray diffraction/X-ray fluorescence instrument. CheMin provided the first in situ X-ray diffraction-based evidence of clay minerals on Mars, which are likely trioctahedral smectites (e.g., Fe-saponite) and comprise 20 wt% of the mudstone samples [1]. SAM's evolved gas analysis (EGA) mass spectrometry analyses of JK and CB subsamples, as well as RN subsamples, detected H2O, CO2, O2, H2, SO2, H2S, HCl, NO, OCS, CS2 and other trace gases evolved during pyrolysis. The identity of evolved gases and temperature( s) of evolution can augment mineral detection by CheMin and place constraints on trace volatile-bearing phases present below the CheMin detection limit or those phases difficult to characterize with XRD (e.g., X-ray amorphous phases). Here we will focus on the SAM H2O data, in the context of CheMin analyses, and comparisons to laboratory SAM-like analyses of several phyllosilicate minerals including smectites.

  18. Even at 4 months, a labial is a good enough coronal, but not vice versa.

    Science.gov (United States)

    Tsuji, Sho; Mazuka, Reiko; Cristia, Alejandrina; Fikkert, Paula

    2015-01-01

    Numerous studies have revealed an asymmetry tied to the perception of coronal place of articulation: participants accept a labial mispronunciation of a coronal target, but not vice versa. Whether or not this asymmetry is based on language-general properties or arises from language-specific experience has been a matter of debate. The current study suggests a bias of the first type by documenting an early, cross-linguistic asymmetry related to coronal place of articulation. Japanese and Dutch 4- and 6-month-old infants showed evidence of discrimination if they were habituated to a labial and then tested on a coronal sequence, but not vice versa. This finding has important implications for both phonological theories and infant speech perception research. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Effect of a kneeling chair on lumbar curvature in patients with low back pain and healthy controls: A pilot study.

    Science.gov (United States)

    Vaucher, Matthieu; Isner-Horobeti, Marie-Eve; Demattei, Christophe; Alonso, Sandrine; Hérisson, Christian; Kouyoumdjian, Pascal; van Dieën, Jaap H; Dupeyron, Arnaud

    2015-06-01

    The concept of an ideal sitting posture is often used in practice but lacks a basis in evidence. We designed a cross-sectional, comparative, matched study to determine the effects of chair and posture on lumbar curvature in 10 patients with chronic non-specific low back pain (CLBP; mean pain duration 24 ± 18 months) and 10 healthy matched controls. Pelvic incidence, sacral slope and lumbar curvature were measured on computed radiographs by 2 blinded clinicians for subjects in 2 postures (upright vs slumped sitting) and on 2 chairs (usual flat chair vs kneeling chair). The reliability of measures was excellent (intraclass correlation coefficient>0.9). As hypothesized, the expected sacral slope and lumbar lordosis changed between standing and sitting on a kneeling chair as compared with a usual chair (Ppostures for lumbar lordosis (P=0.02) indicated more pronounced effects of the chair in slumped sitting. Therefore, lumbar lordosis was reduced less when sitting on a kneeling chair as compared with a usual chair. Although healthy subjects showed more reduction in lordosis between standing and sitting, the chair effect was found in both CLBP patients and healthy subjects. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  20. Considering Children’s Methods of Grasping and Carrying Elementary School Chairs for Easy Carrying, Lifting, and Turning

    Directory of Open Access Journals (Sweden)

    Lu’lu’ Purwaningrum

    2017-01-01

    Full Text Available Carrying, lifting, and turning chairs improve learning activities in schools, which leads to higher quality education. However, it has been shown that elementary school chairs in Indonesia are too heavy for children aged 6 to 9 to easily lift and carry. The present study aimed to investigate children’s methods of carrying chairs as well as lifting and turning them onto desks. Forty-two children (aged 6-9, including 17 Indonesians (6 boys, 11 girls and 25 Japanese (12 boys, 13 girls, participated in the study. The experiment used three elementary school chairs (one Indonesian, two Japanese and two desk types (standard and tall. The most popular method for carrying a chair was to carry it in front of the body with the chair in a lateral position (75%. In all carrying methods, participants showed a preference for grasping two particular points to hold the chair. Children lifted and turned chairs most successfully when they used this popular grasping pattern. The carrying method and the popular grasping pattern for carrying, lifting, and turning chairs need to be considered when redesigning heavy Indonesian elementary school chairs to improve the ease of transport without decreasing the weight.

  1. Quality Improvement Practices in Academic Emergency Medicine: Perspectives from the Chairs

    Directory of Open Access Journals (Sweden)

    DelliFraine, Jami L

    2010-12-01

    Full Text Available Objective: To assess academic emergency medicine (EM chairs’ perceptions of quality improvement (QI training programs.Methods: A voluntary anonymous 20 item survey was distributed to a sample of academic chairs of EM through the Association of Academic Chairs of Emergency Medicine. Data was collected to assess the percentage of academic emergency physicians who had received QI training, the type of training they received, their perception of the impact of this training on behavior, practice and outcomes, and any perceived barriers to implementing QI programs in the emergency department.Results: The response rate to the survey was 69% (N = 59. 59.3% of respondents report that their hospital has a formal QI program for physicians. Chairs received training in a variety of QI programs. The type of QI program used by respondents was perceived as having no impact on goals achieved by QI (χ2 = 12.382; p = 0.260, but there was a statistically significant (χ2 = 14.383; p = 0.006 relationship between whether or not goals were achieved and academic EM chairs’ perceptions about return on investment for QI training. Only 22% of chairs responded that they have already made changes as a result of the QI training. 78.8% of EM chairs responded that quality programs could have a significant positive impact on their practice and the healthcare industry. Chairs perceived that QI programs had the most potential value in the areas of understanding and reducing medical errors and improving patient flow and throughput. Other areas of potential value of QI include improving specific clinical indicators and standardizing physician care.Conclusion: Academic EM chairs perceived that QI programs were an effective way to drive needed improvements. The results suggest that there is a high level of interest in QI but a low level of adoption of training and implementation.[West J Emerg Med. 2010; 11(5:479-485.

  2. Virtues, Vices, and Political Influence in the U.S. Senate.

    Science.gov (United States)

    ten Brinke, Leanne; Liu, Christopher C; Keltner, Dacher; Srivastava, Sameer B

    2016-01-01

    What qualities make a political leader more influential or less influential? Philosophers, political scientists, and psychologists have puzzled over this question, positing two opposing routes to political power--one driven by human virtues, such as courage and wisdom, and the other driven by vices, such as Machiavellianism and psychopathy. By coding nonverbal behaviors displayed in political speeches, we assessed the virtues and vices of 151 U.S. senators. We found that virtuous senators became more influential after they assumed leadership roles, whereas senators who displayed behaviors consistent with vices--particularly psychopathy--became no more influential or even less influential after they assumed leadership roles. Our results inform a long-standing debate about the role of morality and ethics in leadership and have important implications for electing effective government officials. Citizens would be wise to consider a candidate's virtue in casting their votes, which might increase the likelihood that elected officials will have genuine concern for their constituents and simultaneously promote cooperation and progress in government. © The Author(s) 2015.

  3. Vice presidential candidates in the American presidential elections: strategies for selection and effects

    Directory of Open Access Journals (Sweden)

    Marco Morini

    2015-07-01

    Full Text Available American vice presidential candidates are chosen for several reasons. Some of these rationales are easy to be recognized, while others belong to the cockles of the heart of the presidential candidates. Social scientists and journalists agree about the factors that are more essential: the vice presidential (VP nominee’s capacity of balancing the ideological and personal characteristics of the presidential candidate and the “native son” effect, namely the guarantee that the VP nominee would carry his/her own state. These strategies are often combined and they work at different electoral levels: the first one has usually a national or macro-regional significance while the second is crucial in the battleground states. This research is divided into two sections: the first one investigates the “balancing the ticket” strategy, offering an overview of about one century of presidential races. The second aims to verify the VP nominee’s effect in his/her home state. The results will confirm that there have been several running mates who have been selected in order to “balance the ticket” but also that the vice president nominee’s effect in the home states has been quite poor.

  4. Drug delivery from therapeutic self-assembled monolayers (T-SAMs) on 316L stainless steel.

    Science.gov (United States)

    Mahapatro, Anil; Johnson, Dave M; Patel, Devang N; Feldman, Marc D; Ayon, Arturo A; Agrawal, C Mauli

    2008-01-01

    Delivery of therapeutic agents from self-assembled monolayers (SAMs) on 316L stainless steel (SS) has been demonstrated as a viable method to deliver drugs for localized coronary artery stent application. SAMs are highly-ordered, nano-sized molecular coatings, adding 1-10 nm thickness to a surface. Hydroxyl terminated alkanethiol SAMs of 11-mercapto-1-undecanol (-OH SAM) were formed on 316L SS with 48 hr immersion in ethanolic solutions. Attachment of ibuprofen (a model drug) to the functional SAMs was carried out in toluene for 5 hrs at 60 degrees C using Novozume-435 as a biocatalyst. SAM formation and subsequent attachment of ibuprofen was characterized collectively using X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and contact angle (CA) measure-ments. The quantitative in vitro release of ibuprofen into a "physiological" buffer solution was characterized using reverse phase HPLC. Drug release kinetics showed that 14.1 microg of ibuprofen eluted over a period of 35 days with 2.7microg being eluted in the first day and the remaining being eluted over a period of 35 days. The drug release kinetics showed an increase in ibuprofen elution that occurred during first 14 days (2.7microg in 1 day to 9.5 microg in 14 days), following which there was a decrease in the rate of elution. Thus, functional SAMs on 316L SS could be used as tethers for drug attachment and could serve as a drug delivery mechanism from stainless steel implants such as coronary artery stents.

  5. Celiac Disease in Children with Severe Acute Malnutrition (SAM): A Hospital Based Study.

    Science.gov (United States)

    Beniwal, Neetu; Ameta, Gaurav; Chahar, Chandra Kumar

    2017-05-01

    To evaluate the prevalence and clinical features of Celiac disease among children with severe acute malnutrition (SAM). This prospective observational study was conducted in PBM Children Hospital, Bikaner from July 2012 through December 2013. All consecutively admitted children with SAM were recruited. All subjects were screened for Celiac disease by serological test for IgA-anti tissue Transglutaminase (IgA tTG) antibodies. All seropositive children underwent upper gastrointestinal endoscopy for small bowel biopsy for the confirmation. Clinical features of patients with and without celiac disease were compared. The sero-prevalence (IgA tTg positivity) of Celiac disease was found to be 15.38% while prevalence of biopsy confirmed Celiac disease was 14.42% among SAM children. Abdominal distension, diarrhea, anorexia, constipation, pain in abdomen, vitamin deficiencies, edema, clubbing and mouth ulcers were more common in patients of Celiac disease compared to patients without Celiac disease but the difference was statistically significant only for abdominal distension and pain abdomen. There is a high prevalence of Celiac disease in SAM. Screening for Celiac disease (especially in presence of pain abdomen and abdominal distension) should be an essential part of work-up in all children with SAM.

  6. The relative influence of ENSO and SAM on Antarctic Peninsula climate

    Science.gov (United States)

    Clem, Kyle R.; Renwick, James A.; McGregor, James; Fogt, Ryan L.

    2016-08-01

    Recent warming of the Antarctic Peninsula during austral autumn, winter, and spring has been linked to sea surface temperature (SST) trends in the tropical Pacific and tropical Atlantic, while warming of the northeast Peninsula during summer has been linked to a strengthening of westerly winds traversing the Peninsula associated with a positive trend in the Southern Annular Mode (SAM). Here we demonstrate that circulation changes associated with the SAM dominate interannual temperature variability across the entire Antarctic Peninsula during both summer and autumn, while relationships with tropical Pacific SST variability associated with the El Niño-Southern Oscillation (ENSO) are strongest and statistically significant primarily during winter and spring only. We find the ENSO-Peninsula temperature relationship during autumn to be weak on interannual time scales and regional circulation anomalies associated with the SAM more important for interannual temperature variability across the Peninsula during autumn. Consistent with previous studies, western Peninsula temperatures during autumn, winter, and spring are closely tied to changes in the Amundsen Sea Low (ASL) and associated meridional wind anomalies. The interannual variability of ASL depth is most strongly correlated with the SAM index during autumn, while the ENSO relationship is strongest during winter and spring. Investigation of western and northeast Peninsula temperatures separately reveals that interannual variability of northeast Peninsula temperatures is primarily sensitive to zonal wind anomalies crossing the Peninsula and resultant leeside adiabatic warming rather than to meridional wind anomalies, which is closely tied to variability in the zonal portion of the SAM pattern.

  7. A case study of inaccuracy of advanced SAM application in the OPR1000

    Energy Technology Data Exchange (ETDEWEB)

    Roh, Kyung Ho; Yang, Sung Tae; Jung, Ji Eun [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2011-05-15

    KHNP has developed a constrained simulated annealing method to account for the weakness of the least square method when using the SAM calculation for applications related to the OPR1000. The SAM is generated and installed once at the beginning of each cycle. Thus, the accuracy of ASI simulation by CPC is wholly dependent on the accuracy of the SAM constants. As the depletion proceeds, the deviation of the CPC axial power shape increases. When noise is included, the measurement data frequently exceeds the limit (8%) of the CPC ASI deviation. Therefore, KHNP has developed a constrained simulated annealing method to filter the noise from the measurement data and give the SAM a physical meaning. These two objectives form the core of the developed method. The least square method makes it difficult to implement the algorithm for filtering the noise. Thus, a mathematical method that has been used and verified in a variety of fields was adopted for the simulated annealing . In this paper, the relationship between the SAM and CPC axial power shape deviation is analyzed, based on results showing that EOC CPC axial power shape deviation has approached the limit (8%) in the OPR1000 when the simulated annealing method was applied

  8. Virus-Induced Chaperone-Enriched (VICE domains function as nuclear protein quality control centers during HSV-1 infection.

    Directory of Open Access Journals (Sweden)

    Christine M Livingston

    2009-10-01

    Full Text Available Virus-Induced Chaperone-Enriched (VICE domains form adjacent to nuclear viral replication compartments (RC during the early stages of HSV-1 infection. Between 2 and 3 hours post infection at a MOI of 10, host protein quality control machinery such as molecular chaperones (e.g. Hsc70, the 20S proteasome and ubiquitin are reorganized from a diffuse nuclear distribution pattern to sequestration in VICE domains. The observation that VICE domains contain putative misfolded proteins suggests that they may be similar to nuclear inclusion bodies that form under conditions in which the protein quality control machinery is overwhelmed by the presence of misfolded proteins. The detection of Hsc70 in VICE domains, but not in nuclear inclusion bodies, indicates that Hsc70 is specifically reorganized by HSV-1 infection. We hypothesize that HSV-1 infection induces the formation of nuclear protein quality control centers to remodel or degrade aberrant nuclear proteins that would otherwise interfere with productive infection. Detection of proteolytic activity in VICE domains suggests that substrates may be degraded by the 20S proteasome in VICE domains. FRAP analysis reveals that GFP-Hsc70 is dynamically associated with VICE domains, suggesting a role for Hsc70 in scanning the infected nucleus for misfolded proteins. During 42 degrees C heat shock, Hsc70 is redistributed from VICE domains into RC perhaps to remodel viral replication and regulatory proteins that have become insoluble in these compartments. The experiments presented in this paper suggest that VICE domains are nuclear protein quality control centers that are modified by HSV-1 to promote productive infection.

  9. Forget about ergonomics in chair design? Focus on aesthetics and comfort!

    Science.gov (United States)

    Helander, Martin

    Chair users have difficulties distinguishing between chairs of different ergonomics quality. Many ergonomics features that are supposed to relieve discomfort in sitting are indistinguishable because they cannot be perceived. This is due to poor proprioceptive feedback from ligaments, joints and the spine. The joints are relatively insensitive to small changes in angle, and the spine cannot sense differences in pressure due to different body postures. Aesthetics features on the other hand, and features related to comfort and relaxation, are easier to perceive and differentiate. A study of ergonomics chairs verified that users could distinguish between parameters that relate to aesthetics and comfort, but had difficulty in distinguishing between ergonomics features. In the end aesthetics may be more important than ergonomics--at least to the customer who will be guided more by aesthetics than longer-term ergonomic factors.

  10. Molecular junctions based on SAMs of cruciform oligo(phenylene ethynylene)s

    DEFF Research Database (Denmark)

    Wei, Zhongming; Li, Tao; Jennum, Karsten Stein

    2012-01-01

    Cruciform oligo(phenylene ethynylene)s (OPEs) with an extended tetrathiafulvalene (TTF) donor moiety (OPE5-TTF and OPE3-TTF) and their simple analogues (OPE5-S and OPE3) without conjugated substituents were used to form high quality self-assembled monolayers (SAMs) on ultra-flat gold substrates....... Molecular junctions based on these SAMs were investigated using conducting-probe atomic force microscopy (CP-AFM). The TTF substituent changes the molecular orbital energy levels and decreases the HOMO-LUMO energy gap, resulting in a nine-fold increase in conductance for both TTF cruciform OPEs compared...... to the unsubstituted analogues. The difference in electrical transport properties of the SAMs was reproduced by the theoretical transport calculations for the single molecules....

  11. Bringing a Chemical Laboratory Named Sam to Mars on the 2011 Curiosity Rover

    Science.gov (United States)

    Mahaffy, P. R.; Bleacher, L.; Jones, A.; Conrad, P. G.; Cabane, M.; Webster, C. R.; Atreya, S. A.; Manning, H.

    2010-01-01

    An important goal of upcoming missions to Mars is to understand if life could have developed there. The task of the Sample Analysis at Mars (SAM) suite of instruments [1] and the other Curiosity investigations [2] is to move us steadily toward that goal with an assessment of the habitability of our neighboring planet through a series of chemical and geological measurements. SAM is designed to search for organic compounds and inorganic volatiles and measure isotope ratios. Other instruments on Curiosity will provide elemental analysis and identify minerals. SAM will analyze both atmospheric samples and gases evolved from powdered rocks that may have formed billions of years ago with Curiosity providing access to interesting sites scouted by orbiting cameras and spectrometers.

  12. Detection of Organics at Mars: How Wet Chemistry Onboard SAM Helps

    Science.gov (United States)

    Buch, A.; Freissinet, Caroline; Szopa, C.; Glavin, D.; Coll, P.; Cabane, M.; Eigenbrode, J.; Navarro-Gonzalez, R.; Coscia, D.; Teinturier, S.; hide

    2013-01-01

    For the first time in the history of space exploration, a mission of interest to astrobiology could be able to analyze refractory organic compounds in the soil of Mars. Wet chemistry experiment allow organic components to be altered in such a way that improves there detection either by releasing the compounds from sample matricies or by changing the chemical structure to be amenable to analytical conditions. The latter is particular important when polar compounds are present. Sample Analysis at Mars (SAM), on the Curiosity rover of the Mars Science Laboratory mission, has onboard two wet chemistry experiments: derivatization and thermochemolysis. Here we report on the nature of the MTBSTFA derivatization experiment on SAM, the detection of MTBSTFA in initial SAM results, and the implications of this detection.

  13. A Profile of Academic Training Program Directors and Chairs in Radiation Oncology

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Lynn D., E-mail: Lynn.wilson@yale.edu [Department of Therapeutic Radiology, Yale University School of Medicine, Smilow Cancer Hospital, New Haven, Connecticut (United States); Haffty, Bruce G. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Smith, Benjamin D. [Department of Radiation Oncology, UMDNJ-RWJMS, Cancer Institute of New Jersey, New Brunswick, New Jersey (United States)

    2013-04-01

    Purpose: To identify objective characteristics and benchmarks for program leadership in academic radiation oncology. Methods and Materials: A study of the 87 Accreditation Council for Graduate Medical Education radiation oncology training program directors (PD) and their chairs was performed. Variables included age, gender, original training department, highest degree, rank, endowed chair assignment, National Institutes of Health (NIH) funding, and Hirsch index (H-index). Data were gathered from online sources such as departmental websites, NIH RePORTER, and Scopus. Results: There were a total of 87 PD. The median age was 48, and 14 (16%) were MD/PhD. A total of 21 (24%) were female, and rank was relatively equally distributed above instructor. Of the 26 professors, at least 7 (27%) were female. At least 24 (28%) were working at the institution from which they had received their training. A total of 6 individuals held endowed chairs. Only 2 PD had active NIH funding in 2012. The median H-index was 12 (range, 0-51) but the index dropped to 9 (range, 0-38) when those who served as both PD and chair were removed from the group. A total of 76 chairs were identified at the time of the study. The median age was 55, and 9 (12%) were MD/PhD. A total of 7 (9%) of the chairs were female, and rank was professor for all with the exception of 1 who was listed as “Head” and was an associate professor. Of the 76 chairs, at least 10 (13%) were working at the institution from which they received their training. There were a total of 21 individuals with endowed chairs. A total of 13 (17%) had NIH funding in 2012. The median H-index was 29 (range, 3-60). Conclusions: These data provide benchmarks for individuals and departments evaluating leadership positions in the field of academic radiation oncology. Such data are useful for evaluating leadership trends over time and comparing academic radiation oncology with other specialties.

  14. The effectiveness of a chair intervention in the workplace to reduce musculoskeletal symptoms. A systematic review.

    Science.gov (United States)

    van Niekerk, Sjan-Mari; Louw, Quinette Abigail; Hillier, Susan

    2012-08-13

    Prolonged sitting has been associated with musculoskeletal dysfunction. For desk workers, workstation modifications frequently address the work surface and chair. Chairs which can prevent abnormal strain of the neuromuscular system may aid in preventing musculo-skeletal pain and discomfort. Anecdotally, adjustability of the seat height and the seat pan depth to match the anthropometrics of the user is the most commonly recommended intervention. Within the constraints of the current economic climate, employers demand evidence for the benefits attributed to an investment in altering workstations, however this evidence-base is currently unclear both in terms of the strength of the evidence and the nature of the chair features. The purpose of this study was to evaluate the evidence for the effectiveness of chair interventions in reducing workplace musculoskeletal symptoms. Pubmed, Cinahl, Pedro, ProQuest, SCOPUS and PhysioFocus were searched. 'Ergonomic intervention', 'chair', 'musculoskeletal symptoms', 'ergonomics', 'seated work' were used in all the databases. Articles were included if they investigated the influence of chair modifications as an intervention; participants were in predominantly seated occupations; employed a pre/post design (with or without control or randomising) and if the outcome measure included neuro-musculoskeletal comfort and/or postural alignment. The risk of bias was assessed using a tool based on The Cochrane Handbook. Five studies were included in the review. The number of participants varied from 4 to 293 participants. Three of the five studies were Randomised Controlled Trials, one pre and post-test study was conducted and one single case, multiple baselines (ABAB) study was done. Three studies were conducted in a garment factory, one in an office environment and one with university students. All five studies found a reduction in self-reported musculoskeletal pain immediately after the intervention. Bias was introduced due to poor

  15. Data handling with SAM and art at the NOνA experiment

    Science.gov (United States)

    Aurisano, A.; Backhouse, C.; Davies, G. S.; Illingworth, R.; Mayer, N.; Mengel, M.; Norman, A.; Rocco, D.; Zirnstein, J.

    2015-12-01

    During operations, NOvA produces between 5,000 and 7,000 raw files per day with peaks in excess of 12,000. These files must be processed in several stages to produce fully calibrated and reconstructed analysis files. In addition, many simulated neutrino interactions must be produced and processed through the same stages as data. To accommodate the large volume of data and Monte Carlo, production must be possible both on the Fermilab grid and on off-site farms, such as the ones accessible through the Open Science Grid. To handle the challenge of cataloging these files and to facilitate their off-line processing, we have adopted the SAM system developed at Fermilab. SAM indexes files according to metadata, keeps track of each file's physical locations, provides dataset management facilities, and facilitates data transfer to off-site grids. To integrate SAM with Fermilab's art software framework and the NOvA production workflow, we have developed methods to embed metadata into our configuration files, art files, and standalone ROOT files. A module in the art framework propagates the embedded information from configuration files into art files, and from input art files to output art files, allowing us to maintain a complete processing history within our files. Embedding metadata in configuration files also allows configuration files indexed in SAM to be used as inputs to Monte Carlo production jobs. Further, SAM keeps track of the input files used to create each output file. Parentage information enables the construction of self-draining datasets which have become the primary production paradigm used at NOvA. In this paper we will present an overview of SAM at NOvA and how it has transformed the file production framework used by the experiment.

  16. Exploring the impact of a spatial data infrastructure on value-added resellers and vice versa

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2013-08-01

    Full Text Available stream_source_info Cooper_2013_ABSTRACT ONLY.pdf.txt stream_content_type text/plain stream_size 1359 Content-Encoding UTF-8 stream_name Cooper_2013_ABSTRACT ONLY.pdf.txt Content-Type text/plain; charset=UTF-8 Cartography... from Pole to Pole Lecture Notes in Geoinformation and Cartography 2014, pp 395-404 Exploring the Impact of a Spatial Data Infrastructure on Value- Added Resellers and Vice Versa Antony K. Cooper, Serena Coetzee, Petr Rapant, Dominique Laurent...

  17. GoSam: A program for automated one-loop Calculations

    CERN Document Server

    Cullen, G; Heinrich, G; Luisoni, G; Mastrolia, P; Ossola, G; Reiter, T; Tramontano, F

    2012-01-01

    The program package GoSam is presented which aims at the automated calculation of one-loop amplitudes for multi-particle processes. The amplitudes are generated in terms of Feynman diagrams and can be reduced using either D-dimensional integrand-level decomposition or tensor reduction, or a combination of both. GoSam can be used to calculate one-loop corrections to both QCD and electroweak theory, and model files for theories Beyond the Standard Model can be linked as well. A standard interface to programs calculating real radiation is also included. The flexibility of the program is demonstrated by various examples.

  18. GoSam. A program for automated one-loop calculations

    Energy Technology Data Exchange (ETDEWEB)

    Cullen, G. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Greiner, N.; Heinrich, G.; Reiter, T. [Max-Planck-Institut fuer Physik, Muenchen (Germany); Luisoni, G. [Durham Univ. (United Kingdom). Inst. for Particle Physics Phenomenology; Mastrolia, P. [Max-Planck-Institut fuer Physik, Muenchen (Germany); Padua Univ. (Italy). Dipt. di Fisica; Ossola, G. [City Univ. of New York, NY (United States). New York City College of Technology; Tramontano, F. [European Organization for Nuclear Research (CERN), Geneva (Switzerland)

    2011-11-15

    The program package GoSam is presented which aims at the automated calculation of one-loop amplitudes for multi-particle processes. The amplitudes are generated in terms of Feynman diagrams and can be reduced using either D-dimensional integrand-level decomposition or tensor reduction, or a combination of both. GoSam can be used to calculate one-loop corrections to both QCD and electroweak theory, and model files for theories Beyond the Standard Model can be linked as well. A standard interface to programs calculating real radiation is also included. The flexibility of the program is demonstrated by various examples. (orig.)

  19. The nucleation and growth of calcium oxalate monohydrate on self- assembled monolayers (SAMs)

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, A.A.; Tarasevich, B.J.; Graff, G.L.; Fryxell, G.E.; Rieke, P.C.

    1992-05-01

    A physical chemical approach was used to study calcium oxalate monohydrate (COM) nucleation and growth on various organic interfaces. Self-assembling monolayers (SAMs), containing derivatized organic functional groups, were designed to mimic various amino acid residues present in both urine and stone matrix macromolecules. Derivatized surfaces include SAMs with terminal methyl, bromo, imidazole, and thiazolidine-carboxylic acid functional groups. Pronounced differences in COM deposition were observed for the various interfaces with the imidazole and thiazolidine surfaces having the greatest effect and the methyl and bromo groups having little or no nucleating potential.

  20. Rhodium deposition onto a 4-mercaptopyridine SAM on Au(1 1 1)

    Energy Technology Data Exchange (ETDEWEB)

    Manolova, M. [Institute of Electrochemistry, University of Ulm, 89069 Ulm (Germany); Kayser, M. [Institute of Electrochemistry, University of Ulm, 89069 Ulm (Germany); Kolb, D.M. [Institute of Electrochemistry, University of Ulm, 89069 Ulm (Germany)]. E-mail: dieter.kolb@uni-ulm.de; Boyen, H.-G. [Institute of Solid State Physics, University of Ulm, 89069 Ulm (Germany); Ziemann, P. [Institute of Solid State Physics, University of Ulm, 89069 Ulm (Germany); Mayer, D. [BASF Electronic Materials GmbH, 67056 Ludwigshafen (Germany); Wirth, A. [BASF Electronic Materials GmbH, 67056 Ludwigshafen (Germany)

    2007-02-10

    The application of a recently developed method for the deposition of Pd and Pt on top of a SAM, has been successfully extended to Rh, thus proving the versatility of the new concept. Experimental evidence from cyclic voltammetry, in situ STM and ex situ X-ray photoemission spectroscopy is presented for the deposition of monoatomic high rhodium islands onto a 4-mercaptopyridine self-assembled monolayer on a Au(1 1 1) electrode. By repetitive complexation of the Rh ions to the ring-nitrogen and reduction in a Rh-ion free solution, an almost completely covered SAM is obtained. The consequences of making contacts for molecular electronics are briefly discussed.

  1. Damage Simulation Analysis of Discrete Rods to SAM based on FEA

    Directory of Open Access Journals (Sweden)

    Wang Chengcheng

    2015-01-01

    Full Text Available At present ship to air missile is the main force of anti-missile. The warhead damage element’ impact and penetration effect are the main factors for damaging supersonic anti-ship missile (SAM. In this paper, the damage mechanism of the anti-ship missile is studied. Dynamic initial velocity of damage elements is modeled and simulated. The four important parts of SAM with typical material are modeled and simulated based on finite element analysis (FEA. It’s useful to the study of the further model of vulnerability analysis of whole anti-ship missiles.

  2. Changes in SAM2 expression affect lactic acid tolerance and lactic acid production in Saccharomyces cerevisiae.

    Science.gov (United States)

    Dato, Laura; Berterame, Nadia Maria; Ricci, Maria Antonietta; Paganoni, Paola; Palmieri, Luigi; Porro, Danilo; Branduardi, Paola

    2014-10-30

    The great interest in the production of highly pure lactic acid enantiomers comes from the application of polylactic acid (PLA) for the production of biodegradable plastics. Yeasts can be considered as alternative cell factories to lactic acid bacteria for lactic acid production, despite not being natural producers, since they can better tolerate acidic environments. We have previously described metabolically engineered Saccharomyces cerevisiae strains producing high amounts of L-lactic acid (>60 g/L) at low pH. The high product concentration represents the major limiting step of the process, mainly because of its toxic effects. Therefore, our goal was the identification of novel targets for strain improvement possibly involved in the yeast response to lactic acid stress. The enzyme S-adenosylmethionine (SAM) synthetase catalyses the only known reaction leading to the biosynthesis of SAM, an important cellular cofactor. SAM is involved in phospholipid biosynthesis and hence in membrane remodelling during acid stress. Since only the enzyme isoform 2 seems to be responsive to membrane related signals (e.g. myo-inositol), Sam2p was tagged with GFP to analyse its abundance and cellular localization under different stress conditions. Western blot analyses showed that lactic acid exposure correlates with an increase in protein levels. The SAM2 gene was then overexpressed and deleted in laboratory strains. Remarkably, in the BY4741 strain its deletion conferred higher resistance to lactic acid, while its overexpression was detrimental. Therefore, SAM2 was deleted in a strain previously engineered and evolved for industrial lactic acid production and tolerance, resulting in higher production. Here we demonstrated that the modulation of SAM2 can have different outcomes, from clear effects to no significant phenotypic responses, upon lactic acid stress in different genetic backgrounds, and that at least in one genetic background SAM2 deletion led to an industrially relevant

  3. A new application of SAM in the non-destructive inspection for SIM card

    Science.gov (United States)

    Cai, Bin; He, Yandong; Zhao, Yang; Chen, Yanning; Zhang, Haifeng; Zhao, Dongyan

    2017-07-01

    Scanning Acoustic Microscopy (SAM) is a typical inspection method in the semiconductor IC manufacturing industry. Because the die thickness is a key parameter for SIM card, a new method to measure the internal die thickness of SIM card is proposed with SAM’s reflective scanning mode. Using this method the internal die thickness of SIM card can be accurately measured without introducing any damages to SIM card. The thickness model and methodology based on the SAM signals have been established. The model was properly verified and calibrated by two real test cases.

  4. Listening to Voices at the Educational Frontline: New Administrators’ Experiences of the Transition from Teacher to Vice-principal

    Directory of Open Access Journals (Sweden)

    Denise Armstrong

    2015-10-01

    Full Text Available This qualitative study examined the transition from teaching to administration through the voices four novice vice-principals. An integrative approach was used to capture the interaction between new vice-principals, their external contexts, and the resulting leadership outcomes. The data revealed that in spite of these new administrators’ intention to create better schools for all students, they encountered multiple factors that hindered their ability to achieve their leadership goals. Key obstacles included the ambiguous legal and institutional configuration of the vice-principalship, inadequate preparation for challenging front line managerial and disciplinary roles, and inappropriate transitional support. Through listening to new vice-principals voices and providing relevant preparation and coordinated supports, school districts and policy makers can improve this transition and address some of the leadership challenges facing schools.

  5. 5 CFR 315.602 - Appointment based on service in the Office of the President or Vice-President or on the White...

    Science.gov (United States)

    2010-01-01

    ... Office of the President or Vice-President or on the White House Staff. 315.602 Section 315.602... service in the Office of the President or Vice-President or on the White House Staff. (a) Agency authority... Office of the President or Vice-President or on the White House Staff, provided that the appointment is...

  6. Sugar in disguise or healthy indulgence: A cross-cultural comparision of the perceptions of dietary vice/virtue bundles

    Directory of Open Access Journals (Sweden)

    Jiraporn Napatsorn

    2016-07-01

    Full Text Available Consumers often choose virtue food to attain health goals and vice food to achieve indulgence goals. However, food and beverage companies have begun to nullify the vice and virtue categories by bundling vice and virtue ingredients into a single item (e.g. Yogurt with Oreo topping. This research contrasts how consumers from Asian and Western cultures evaluate such vice/virtue food bundles. Building on the perceptual processes and regulatory focus literatures, two cross-cultural experiments using participants in Thailand and the U.S. shows that Westerners prefer virtue-heavy bundles to vice-heavy bundles while Asians show similar preference across both types of bundle. Process measures revealed that Asians perceive greater fit between vice and virtue components in the bundles than Westerners and this perceived fit mediates the effect of culture on their food choice. Study 2 reveals the boundary condition. Specifically, when regulatory focus was manipulated, the effect of culture is no longer significant. The findings provide managerial implications for food and beverage companies as well as contributions to consumer behavior literature.

  7. Analysis of the interactions between host factor Sam68 and viral elements during foot-and-mouth disease virus infection

    Science.gov (United States)

    The nuclear protein Src-associated protein of 68 kDa in mitosis (Sam68) is known to bind RNA and be involved in cellular processes triggered in response to environmental stresses, including virus infection. Interestingly, Sam68, is a multi-functional protein implicated in the life cycle of retroviru...

  8. "SAMs meet MEMS": surface modification with self-assembled monolayers for the dry-demolding of photoplastic MEMS/NEMS

    NARCIS (Netherlands)

    Kim, B.J.; Kim, G.M.; Liebau, M.; Huskens, Jurriaan; Reinhoudt, David; Brugger, J.P.

    2001-01-01

    In this contribution we demonstrate the use of self-assembled monolayers (SAMs) as anti-adhesion coating to assist the removal of photoplastic MEMS/NEMS with a patterned metal layer from the surface without wet chemical sacrificial layer etching, so-called 'dry-demolding'. The SAMs functionality

  9. Impact of Vice President Cheney on public interest in left ventricular assist devices and heart transplantation.

    Science.gov (United States)

    Pandey, Ambarish; Abdullah, Kazeen; Drazner, Mark H

    2014-05-01

    Although celebrity illnesses attract a significant amount of media attention in the United States, there are few studies that have looked at how celebrity health conditions impact the awareness of the illness in the general population. Recently, Vice President Cheney underwent left ventricular assist device (LVAD) implantation and subsequently a cardiac transplant. The aim of this study was to determine whether there was evidence of increased interest in these 2 procedures as assessed by social media. We determined the relative frequency of Google searches for LVAD and heart transplantation from 2004 to 2013 using Google trends. We also counted the number of YouTube videos and Twitter messages posted monthly concerning LVADs over a 7-year time frame. There was a significant spike in the Google search interest for LVAD and heart transplantation in the month when Vice President Cheney underwent the respective procedure. Similarly, there was a large increase in YouTube videos and Twitter messages concerning LVADs shortly after he was implanted. In total, these data support the concept that a public figure's illness can significantly influence the public's interest in that condition and its associated therapies. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. An attempt to appoint a Swedish vice consul to Bucharest (1834-1835

    Directory of Open Access Journals (Sweden)

    Veniamin Ciobanu

    2012-08-01

    Full Text Available The economic development of Sweden at the end of the second decade of the nineteenth century accentuated the interest of the Swedish ruling circles to valorize the new economic potential. A series of measures, as the dissolution of the terrestrial customs between Sweden and Norway in 1825, or the abolition of the protectionist policy in imports, opened the way for the conclusion of certain commercial treaties with other states, such as that with Great Britain in 1826 or with the Ottoman Empire in 1827. Consequently, the commercial fleet, especially the Norwegian one, registered a substantial development. In this context, the Swedish diplomacy continued to pay close attention to Eastern Europe where favorable conditions for the extension of the foreign trade of Sweden and Norway could be found. This space, where the Romanian Principalities were located, had a geostrategic position and economic potential that had to be valorized. In order to achieve this goal, Sweden appointed consuls and vice consuls in the Romanian Principalities. The attempt to appoint a vice consul to Bucharest between 1834 and 1835 circumscribes this effort. The information regarding these demarches came from Swedish diplomatic reports, held in the funds of the National Archives of Sweden (Sveriges Riksarkivet, from Stockholm and offers, among many other details which may serve to broaden the horizon of the research regarding the history of Romanian-Swedish relations in the first half of the nineteenth century, an image of the Lutheran community from the capital of Wallachia.

  11. Coexistence of Wormian Bones With Metopism, and Vice Versa, in Adult Skulls.

    Science.gov (United States)

    Cirpan, Sibel; Aksu, Funda; Mas, Nuket; Magden, Abdurrahman Orhan

    2016-03-01

    The aim of the study is to investigate coexistence of Wormian bones with metopism, and vice versa, in adult skulls. A total of 160 dry adult human skulls of unknown sex and ages were randomly selected from the Gross Anatomy Laboratory of Medical School of Dokuz Eylul University. The skulls were examined for presence of metopism, Wormian bones (WB), and coexistence of WBs with metopism and vice versa. Topographic distribution of the WBs was macroscopically evaluated within the skulls including metopism. The photographs were being taken with Canon 400B (55 mm objective). The frequency of metopism and WBs in 160 skulls is 7.50% (12/160) and 59.3% (95/160), respectively, P coexistence of WBs with metopism was found as 11 of 12 skulls (91.66%), whereas the incidence of coexistence of metopism with WBs was found as 11 of 95 skulls (11.58%), P coexistence of WBs with metopism (11/12, 91.66%) and coexistence of metopism with WBs (11/95, 11.58%). The factors leading to metopism may also lead to WBs, whereas that the factors leading to WBs may not lead to metopism.

  12. Jacqueline Baxter Talks to Gill Howland, Newly Appointed Chair of BELMAS

    Science.gov (United States)

    Baxter, Jacqueline

    2017-01-01

    Gill is currently Chair of the British Educational Leadership, Management and Administration Society. Her personal experiences are central to her belief that education is the key to unlocking potential, both for individuals and for society as a whole. Throughout her career she has championed the right to good quality, inspirational education for…

  13. 78 FR 59012 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2013-09-25

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... environmental restoration, waste management, and related activities. Tentative Agenda Topics: Wednesday, October...

  14. 76 FR 62054 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2011-10-06

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open teleconference. SUMMARY: This notice announces a teleconference of the Environmental Management... make recommendations to DOE-EM and site management in the areas of environmental restoration, waste...

  15. 76 FR 17118 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2011-03-28

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... Board is to make recommendations to DOE-EM and site management in the areas of environmental restoration...

  16. 78 FR 64208 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2013-10-28

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... environmental restoration, waste management, and related activities. Tentative Agenda Topics: Tuesday, November...

  17. 78 FR 20311 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2013-04-04

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of Open Webinar. SUMMARY: This notice announces a webinar of the Environmental Management Site-Specific... recommendations to DOE-EM and site management in the areas of environmental restoration, waste management, and...

  18. 77 FR 55813 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2012-09-11

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... Board is to make recommendations to DOE-EM and site management in the areas of environmental restoration...

  19. 75 FR 51450 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2010-08-20

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... the Board is to make recommendations ] to DOE-EM and site management in the areas of environmental...

  20. Tenure Standards in Political Science Departments: Results from a Survey of Department Chairs

    Science.gov (United States)

    Rothgeb, John M., Jr.; Burger, Betsy

    2009-01-01

    This article presents the results from a survey of political science department chairs regarding the tenure procedures and standards at their colleges or universities. The findings reveal that only a small fraction of the colleges and universities in the United States refuse to offer tenure or are attempting to limit tenure. We also find general…

  1. The role of chair exercises for older adults following hip fracture ...

    African Journals Online (AJOL)

    The role of chair exercises for older adults following hip fracture. ... 3.5)), sedentary (mean score on Habitual Physical Activity Questionnaire for the Elderly 7.4 (SO 3.3)) women aged 70 years and above (mean 80 (SO 6.6) years). ... Both groups improved similarly in grip strength, and in levels of depression and confidence.

  2. Design of Lesehan Chair by Using Kansei Engineering Method And Anthropometry Approach

    Science.gov (United States)

    Pambudi, A. T.; Suryoputro, M. R.; Sari, A. D.; Kurnia, R. D.

    2016-01-01

    Special Region of Yogyakarta (DIY) is known as city for academic. Many people come to get some education in college. They live in boarding house with some supporting facilities. The most common facilities is low table which lead students have to sit on the floor while studying on table which could cause higher risk of back pain and musculoskeletal disorder. To identify the solution to reduce back pain and musculoskeletal risk, it is needed to design a lesehan chair which also appropriate to customer needs. Kansei engineering method was used with a total of 30 respondents participated, 15 kansei words collected, and 12 kansei words selected by doing validation and reliability test. The result of this study showed that quality, aesthetics, and comfort level influence the design of lesehan chair. A design of lesehan chair was created by considering the suitable concept and merging it with the physical design and its anthropometry measurement. In this case, marginal homogeneity test is needed to identify the differences between each kansei words attribute and the design or product recommendation. The marginal homogeneity test results show that the design and product recommendation has fulfilled customer's desires and needs. For further research, it is needed to analyse and evaluate the posture of lesehan chair users in order to develop and improve its performance.

  3. University-Supervised Chair Work as a Form of School and Pedagogical University Collaboration

    Science.gov (United States)

    Chekaleva, Nadezhda V.; Duka, Natalia A.; Drobotenko, Julia B.; Makarova, Natalia S.; Solovev, Dmitrii N.; Soloveva, Tatiana O.; Fetter, Inna V.

    2016-01-01

    The main tendencies of pedagogical education are discussed in the article. Modern tendencies and qualifying norms to the future teacher make the opportunities for strengthening of practical orientation of higher education. The key types of university-supervised chair (unilateral and bilateral cooperation) are considered and their work is…

  4. Views from a Distance: A Nephological Model of the CCCC Chairs' Addresses, 1977-2011

    Science.gov (United States)

    Mueller, Derek N.

    2012-01-01

    Views from a Distance is a series of word clouds rendered from 35 chairs' addresses delivered at CCCC conventions from 1977 to 2011. The digital installation invites explorations of word-level patterns and anomalies within this widely recognized collection of speeches. The installation itself is underpinned with the assumption that distinctive…

  5. 76 FR 30695 - Environmental Management Site-Specific Advisory Board Chairs

    Science.gov (United States)

    2011-05-26

    ..., 2011, 8 a.m.-5 p.m. and Thursday, June 16, 2011, 8 a.m.-12:30 p.m. ADDRESSES: Aliante Station Hotel... Headquarters Budget Update, EM Headquarters Waste Disposition Update, EM SSAB Chairs' Roundtable Discussion...

  6. Higher Education Department Chairs and Academic Human Resource Decision Making: Does Unionization Matter?

    Science.gov (United States)

    Dzwik, Leigh Settlemoir

    2017-01-01

    The purpose of this study was to assess faculty unionization's impact on academic human resource decision making for department chairs. The academic human resource decisions included in the study were: academic hiring; re-employment, promotion and tenure; other faculty evaluation decisions; and discipline and discharge. The first purpose of this…

  7. The Canada Research Chairs Program: The Good, the Bad, and the Ugly

    Science.gov (United States)

    Grant, Karen R.; Drakich, Janice

    2010-01-01

    Drawing on 60 qualitative interviews with Canada research chairs (CRCs), we explore their careers in context. We develop a model to understand the intersection of individual and institutional factors that shape the everyday experiences of the CRCs. The model shows the dialectical relationship between faculty identity, research, relations with…

  8. The Stressful Journey of the Department Chair: An Academic in Need of a Compass and Clock.

    Science.gov (United States)

    Gmelch, Walter H.; Gates, Gordon S.

    This study examined the relationship between five stress factors (faculty role, administrative relationship, role ambiguity, perceived expectations, and administrative task) and specific personal, positional, and organizational variables in relation to their effect on the roles of department chairpersons. Using a chair stress index, administrative…

  9. Infection Control in dental practice for chair-side Assistants in ...

    African Journals Online (AJOL)

    Aim of the course: The aim of the course was to train and orient the chair-side assistants on cross-infection control in dental practice. The scope and implementation of the course: This is a two weeks course that covers principles and procedures for infection control in dental practice. The participants are guided through a ...

  10. Shifts in the focus of population policies: concluding remarks on the XXXV Chaire Quetelet Symposium

    NARCIS (Netherlands)

    van Nimwegen, N.

    2011-01-01

    The symposium, “Population Policies in Europe and in North America”, XXXV Chaire Quetelet, Louvain-la-Neuve, 18-20 October 2009, covered a wide range of studies treating major issues on the interface of population trends and policy implications. The studies reported ranged from migration to family

  11. The Role of the Chair of the School Governing Body in England

    Science.gov (United States)

    James, Chris; Jones, Jeff; Connolly, Michael; Brammer, Steve; Fertig, Mike; James, Jane

    2012-01-01

    The research reported here analysed the role of the chair of the school governing body in England, drawing on a national survey of governors and the study of governing in 30 schools. The role encompassed: being a governor; appointing and working with the head teacher; acting as a change agent; active participation in the school; organising the…

  12. Evaluating Design Enhancements to the Tablet Arm Chair in Language Instruction Classes at UNC Chapel Hill

    Science.gov (United States)

    Henshaw, Robert Griffith; Reubens, Andrea

    2014-01-01

    Higher education institutions are increasingly interested in cost-effective classroom furniture solutions that support diverse teaching methods by facilitating movement between lecture and interactive instructional methods such as small group work. Several furniture manufacturers are exploring designs based on the traditional tablet arm chair. A…

  13. Reliability of Arm Curl and Chair Stand tests for assessing muscular endurance in older people

    Directory of Open Access Journals (Sweden)

    Boneth M

    2012-05-01

    Full Text Available Objective: to assess the test-retest reliability and level of agreement between measures of the 30 second (30-s Arm Curl and 30-s Chair Stand test in a sample of older adults from Bucaramanga. Materials and methods: a study of evaluation of diagnostic technology was done. Both tests were administered by the same evaluator to 111 adults older than 59 year-old (70,4 ± 7,3, on two occasions, with an interval of time between measures of 4 to 8 days. In the analysis, test-retest reliability was determined using the Intraclass Correlation Coefficient ICC= 2,1 with their confidence interval 95% (CI 95% respective. The agreement level was established by the Bland and Altman method. Results: the test-retest reproducibility of the 30-s Arm Curl test was very good ICC= 0,88 and to the Chair Stand test was good ICC= 0,78. The agreement was very good for both tests of muscle endurance. The CI 95% were between -3,8 and 3,2 stands to 30-s Chair Stand test and between -3,1 and 2,8 curls to 30-s Arm Curl test. Conclusion: the 30-s Arm Curl and 30-s Chair Stand test have good reliability and agreement to assess muscle endurance in older adults functionally independent.

  14. Vestibulo-cardiorespiratory responses at the onset of chair rotation in endurance runners.

    Science.gov (United States)

    Sato, Kohei; Katayama, Keisho; Katayama, Naomi; Hotta, Norio; Ishida, Koji; Miyamura, Miharu

    2005-02-01

    Stimulation of the vestibular system has been reported to elicit ventilatory and circulatory changes in humans. The purpose of this study was to clarify the characteristics of vestibular-mediated ventilatory and circulatory responses in male endurance runners at the onset of passive chair rotation, which selectively stimulates the semicircular canals. Fourteen runners and 14 male untrained subjects participated. The vestibular stimulus test, which consists of 180 degrees chair rotations (left or right half-turns on an earth-vertical axis) for a duration of 2 s, was carried out on each subject. Inspiratory minute ventilation, tidal volume, respiratory frequency, heart rate, and blood pressure were measured by breath-by-breath and beat-to-beat techniques before, during, and after the chair rotation for a total of 60 s. It was found in this study that (i) the relative change of minute ventilation response in the endurance runners was significantly (P untrained subjects during and after the rotation, and that (ii) no significant group differences were observed in heart rate and mean blood pressure responses during and after the rotation. In conclusion, vestibular-mediated ventilatory response, but not circulatory response, at the onset of the chair rotation in the endurance runners was significantly greater than that in the untrained subjects. The results from the present study suggest that an increase in vestibulo-ventilatory response would be attributed to an adaptation to long-term endurance training.

  15. Strategic Planning in a Health Leadership Sector: A Report from UNESCO Chair in Health Education, Iran

    OpenAIRE

    K Bidad; F Farzadi; Pourpak, Z.; Moin, M.

    2009-01-01

    "nStrategic planning defines the formal decision of a company for its future. Like all organizations, health care sectors need to prepare their strategic planning and act according to it. UNESCO chair in health edu­cation as a leader health sector, describes the course and steps for preparing its strategic planning based on SWOT analysis technique. 

  16. Principals Fostering the Instructional Leadership Capacities of Department Chairs: A Strategy for Urban High School Reform

    Science.gov (United States)

    Klar, Hans W.

    2013-01-01

    A growing body of literature has highlighted the affordances of distributive forms of instructional leadership as a means to broaden and deepen instructional leadership capacity within schools. Yet, specifically how the capabilities of such key leaders as high school department chairs can be fostered to realize enhanced instructional capacity…

  17. Observation of Classroom Performance Using Therapy Balls as a Substitute for Chairs in Elementary School Children

    Science.gov (United States)

    Burgoyne, Molly E.; Ketcham, Caroline J.

    2015-01-01

    Many classrooms are beginning to substitute standard chairs with therapy balls, which help to improve students' focus and classroom performance, according to teacher and student reports. Researchers conducted an observational study in a classroom at a local elementary school that implemented therapy balls. For each hour-long observation, three…

  18. Converting Chair-like Transition States into Zig-Zag Projections A ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 9. Converting Chair-like Transition States into Zig-Zag Projections: A Method of Drawing Stereochemical Structures. Syed R Hussaini. Classroom Volume 19 Issue 9 September 2014 pp 846-850 ...

  19. Perceptions of Value-Congruence with One's Department Chair: Does Match Matter?

    Science.gov (United States)

    Virick, Meghna; Strage, Amy

    2016-01-01

    Although studies have examined numerous factors that predict junior faculty success, previous research has paid little attention to the role played by department chairs. Drawing on theory from person-environment fit theory and value congruence, we sought to examine the implication of a match versus mismatch between faculty members and their chairs…

  20. Severe cerebral desaturation during shoulder arthroscopy in the beach-chair position

    DEFF Research Database (Denmark)

    Dippmann, Christian; Winge, Søren; Nielsen, Henning Bay

    2010-01-01

    During shoulder arthroscopy in the beach-chair position, cerebral ischemia may be a serious complication because prolonged hypotension may affect regional cerebral oxygen supply. We present the cases of 2 patients in whom a reduction in mean arterial pressure after anesthesia provoked a decrease ...

  1. [The call of Viktor von Weizsäckers to the chair for neurology in Breslau 1941].

    Science.gov (United States)

    Benzenhöfer, U

    1994-11-01

    Only five chairs especially for neurology were existing in Germany in 1938. In this paper the history of the call of Viktor von Weizsäcker (1886-1957) to the famous Breslau chair (Otfrid Foerster) in 1941 is described in detail using unpublished material from the Reichsministerium für Wissenschaft, Erziehung und Volksbildung.

  2. An Investigation of the National School Board Association Key Work Standards for Public Policy Leadership and School Board Chair Performance

    Science.gov (United States)

    Quarles, Roger C.

    2011-01-01

    This multiple case qualitative study addressed the National School Board Association's (NSBA) Key Work standards for public policy leadership by local school boards, and how three elite school board chairs understood and implemented those standards. Elite board chair status was defined by experience, training, and peer recognition. The study…

  3. 75 FR 44767 - Folding Metal Tables and Chairs From the People's Republic of China: Initiation of New Shipper...

    Science.gov (United States)

    2010-07-29

    ... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China... metal tables and chairs (``FMTCs'') from the People's Republic of China (``PRC''), received on June 30... published in the Federal Register on June 27, 2002. See Antidumping Duty Order: Folding Metal Tables and...

  4. The effectiveness of a chair intervention in the workplace to reduce musculoskeletal symptoms. A systematic review

    Directory of Open Access Journals (Sweden)

    van Niekerk Sjan-Mari

    2012-08-01

    Full Text Available Abstract Background Prolonged sitting has been associated with musculoskeletal dysfunction. For desk workers, workstation modifications frequently address the work surface and chair. Chairs which can prevent abnormal strain of the neuromuscular system may aid in preventing musculo-skeletal pain and discomfort. Anecdotally, adjustability of the seat height and the seat pan depth to match the anthropometrics of the user is the most commonly recommended intervention. Within the constraints of the current economic climate, employers demand evidence for the benefits attributed to an investment in altering workstations, however this evidence-base is currently unclear both in terms of the strength of the evidence and the nature of the chair features. The purpose of this study was to evaluate the evidence for the effectiveness of chair interventions in reducing workplace musculoskeletal symptoms. Methods Pubmed, Cinahl, Pedro, ProQuest, SCOPUS and PhysioFocus were searched. ‘Ergonomic intervention’, ‘chair’, ‘musculoskeletal symptoms’, ‘ergonomics’, ‘seated work’ were used in all the databases. Articles were included if they investigated the influence of chair modifications as an intervention; participants were in predominantly seated occupations; employed a pre/post design (with or without control or randomising and if the outcome measure included neuro-musculoskeletal comfort and/or postural alignment. The risk of bias was assessed using a tool based on The Cochrane Handbook. Results Five studies were included in the review. The number of participants varied from 4 to 293 participants. Three of the five studies were Randomised Controlled Trials, one pre and post-test study was conducted and one single case, multiple baselines (ABAB study was done. Three studies were conducted in a garment factory, one in an office environment and one with university students. All five studies found a reduction in self-reported musculoskeletal pain

  5. cljam: a library for handling DNA sequence alignment/map (SAM) with parallel processing.

    Science.gov (United States)

    Takeuchi, Toshiki; Yamada, Atsuo; Aoki, Takashi; Nishimura, Kunihiro

    2016-01-01

    Next-generation sequencing can determine DNA bases and the results of sequence alignments are generally stored in files in the Sequence Alignment/Map (SAM) format and the compressed binary version (BAM) of it. SAMtools is a typical tool for dealing with files in the SAM/BAM format. SAMtools has various functions, including detection of variants, visualization of alignments, indexing, extraction of parts of the data and loci, and conversion of file formats. It is written in C and can execute fast. However, SAMtools requires an additional implementation to be used in parallel with, for example, OpenMP (Open Multi-Processing) libraries. For the accumulation of next-generation sequencing data, a simple parallelization program, which can support cloud and PC cluster environments, is required. We have developed cljam using the Clojure programming language, which simplifies parallel programming, to handle SAM/BAM data. Cljam can run in a Java runtime environment (e.g., Windows, Linux, Mac OS X) with Clojure. Cljam can process and analyze SAM/BAM files in parallel and at high speed. The execution time with cljam is almost the same as with SAMtools. The cljam code is written in Clojure and has fewer lines than other similar tools.

  6. Initial SAM Calibration Gas Experiments on Mars: Quadrupole Mass Spectrometer Results and Implications

    Science.gov (United States)

    Franz, Heather B.; Trainer, Melissa G.; Malespin, Charles A.; Mahaffy, Paul R.; Atreya, Sushil K.; Becker, Richard H,; Benna, Mehdi; Conrad, Pamela G.; Eigenbrode, Jennifer L.; Freissinet, Caroline; hide

    2017-01-01

    The Sample Analysis at Mars (SAM) instrument suite of the Mars Science Laboratory (MSL) Curiosity rover is equipped to analyze both martian atmospheric gases and volatiles released by pyrolysis of solid surface materials, with target measurements including chemical and isotopic composition (Mahaffy et al., 2012). To facilitate assessment of instrument performance and validation of results obtained on Mars, SAM houses a calibration cell containing CO2, Ar, N2, Xe, and several fluorinated hydrocarbon compounds (Franz et al., 2014; Mahaffy et al., 2012). This report describes the first two experiments utilizing this calibration cell on Mars and gives results from analysis of data acquired with the SAM Quadrupole Mass Spectrometer (QMS). These data support the accuracy of isotope ratios obtained with the QMS (Conrad et al., 2016; Mahaffy et al., 2013) and provide ground-truth for reassessment of analytical constants required for atmospheric measurements, which were reported in previous contributions (Franz et al., 2015, 2014). The most significant implication of the QMS data involves reinterpretation of pre-launch contamination previously believed to affect only CO abundance measurements (Franz et al., 2015) to affect N2 abundances, as well. The corresponding adjustment to the N2 calibration constant presented here brings the atmospheric volume mixing ratios for Ar and N2 retrieved by SAM into closer agreement with those reported by the Viking mission (Owen et al., 1977; Oyama and Berdahl, 1977).

  7. Initial SAM calibration gas experiments on Mars: Quadrupole mass spectrometer results and implications

    Science.gov (United States)

    Franz, Heather B.; Trainer, Melissa G.; Malespin, Charles A.; Mahaffy, Paul R.; Atreya, Sushil K.; Becker, Richard H.; Benna, Mehdi; Conrad, Pamela G.; Eigenbrode, Jennifer L.; Freissinet, Caroline; Manning, Heidi L. K.; Prats, Benito D.; Raaen, Eric; Wong, Michael H.

    2017-04-01

    The Sample Analysis at Mars (SAM) instrument suite of the Mars Science Laboratory (MSL) Curiosity rover is equipped to analyze both martian atmospheric gases and volatiles released by pyrolysis of solid surface materials, with target measurements including chemical and isotopic composition (Mahaffy et al., 2012). To facilitate assessment of instrument performance and validation of results obtained on Mars, SAM houses a calibration cell containing CO2, Ar, N2, Xe, and several fluorinated hydrocarbon compounds (Franz et al., 2014; Mahaffy et al., 2012). This report describes the first two experiments utilizing this calibration cell on Mars and gives results from analysis of data acquired with the SAM Quadrupole Mass Spectrometer (QMS). These data support the accuracy of isotope ratios obtained with the QMS (Conrad et al., 2016; Mahaffy et al., 2013) and provide ground-truth for reassessment of analytical constants required for atmospheric measurements, which were reported in previous contributions (Franz et al., 2015, 2014). The most significant implication of the QMS data involves reinterpretation of pre-launch contamination previously believed to affect only CO abundance measurements (Franz et al., 2015) to affect N2 abundances, as well. The corresponding adjustment to the N2 calibration constant presented here brings the atmospheric volume mixing ratios for Ar and N2 retrieved by SAM into closer agreement with those reported by the Viking mission (Owen et al., 1977; Oyama and Berdahl, 1977).

  8. How Safe is Sam Lloyd's Bet? The 15-Puzzle and Beyond

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 11. How Safe is Sam Lloyd's Bet? The 15-Puzzle and Beyond. Jyoti Ramakrishnan. Classroom Volume 5 Issue 11 November 2000 pp 80-89. Fulltext. Click here to view fulltext PDF. Permanent link:

  9. Case Studies Comparing System Advisor Model (SAM) Results to Real Performance Data: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Blair, N.; Dobos, A.; Sather, N.

    2012-06-01

    NREL has completed a series of detailed case studies comparing the simulations of the System Advisor Model (SAM) and measured performance data or published performance expectations. These case studies compare PV measured performance data with simulated performance data using appropriate weather data. The measured data sets were primarily taken from NREL onsite PV systems and weather monitoring stations.

  10. Constraints on the Mineralogy of Gale Crater Mudstones from MSL SAM Evolved Water

    Science.gov (United States)

    McAdam, A. C.; Sutter, B.; Franz, H. B.; Hogancamp, J. V. (Clark); Knudson, C. A.; Andrejkovicova, S.; Archer, P. D.; Eigenbrode, J. L.; Ming, D. W.; Mahaffy, P. R.

    2017-01-01

    The Sample Analysis at Mars (SAM) and Chemistry and Mineralogy (CheMin) instruments on the Mars Science Laboratory (MSL) have analysed more than 150 micron fines from 14 sites at Gale Crater. Here we focus on the mudstone samples. Two were drilled from sites John Klein (JK) and Cumberland (CB) in the Sheepbed mudstone. Six were drilled from Murray Formation mudstone: Confidence Hills (CH), Mojave (MJ), Telegraph Peak (TP), Buckskin (BK), Oudam (OU), Marimba (MB). SAM's evolved gas analysis mass spectrometry (EGA-MS) detected H2O, CO2, O2, H2, SO2, H2S, HCl, NO, and other trace gases, including organic fragments. The identity and evolution temperature of evolved gases can support CheMin mineral detection and place constraints on trace volatile-bearing phases or phases difficult to characterize with X-ray diffraction (e.g., amorphous phases). Here we will focus on SAM H2O data and comparisons to SAM-like analyses of key reference materials.

  11. Stealing the gold a celebration of the pioneering physics of Sam Edwards

    CERN Document Server

    Goldenfeld, Nigel; Sherrington, D C; Edwards, S F

    2004-01-01

    This title presents a survey of some of the most exciting topics in condensed matter physics today, from the perspective of the pioneering work of Sam Edwards. Original articles from leaders in the field highlight the historical development as well as new and emerging areas.

  12. Cross-Reactive Sensor Array for Metal Ion Sensing Based on Fluorescent SAMs

    Directory of Open Access Journals (Sweden)

    Mercedes Crego-Calama

    2007-09-01

    Full Text Available Fluorescent self assembled monolayers (SAMs on glass were previouslydeveloped in our group as new sensing materials for metal ions. These fluorescent SAMs arecomprised by fluorophores and small molecules sequentially deposited on a monolayer onglass. The preorganization provided by the surface avoids the need for complex receptordesign, allowing for a combinatorial approach to sensing systems based on small molecules.Now we show the fabrication of an effective microarray for the screening of metal ions andthe properties of the sensing SAMs. A collection of fluorescent sensing SAMs wasgenerated by combinatorial methods and immobilized on the glass surfaces of a custom-made 140 well microtiter-plate. The resulting libraries are easily measured and show variedresponses to a series cations such as Cu2+ , Co2+ , Pb2+ , Ca2+ and Zn2+ . These surfaces are notdesigned to complex selectively a unique analyte but rather they are intended to producefingerprint type responses to a range of analytes by less specific interactions. The unselectiveresponses of the library to the presence of different cations generate a characteristic patternfor each analyte, a “finger print” response.

  13. A Normalizing Approach to Cognitive Therapy for Intrusive Obsessional and Psychotic Phenomena: The Case of Sam

    Science.gov (United States)

    Morrison, Anthony P.

    2005-01-01

    The case of Sam is conceptualized using a normalizing cognitive approach, which assumes that the cultural acceptability of his appraisals distinguishes them as psychotic. The treatment approach that is based upon such a case formulation involves the evaluation of such distressing appraisals and the generation of alternative explanations.…

  14. Making Time for Instructional Leadership. Volume 1: The Evolution of the SAM Process

    Science.gov (United States)

    Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Murphy, Joseph; Blissett, Richard; Porter, Andy

    2015-01-01

    This three-volume report describes the "SAM (School Administration Manager) process," an approach that about 700 schools around the nation are using to direct more of principals' time and effort to improve teaching and learning in classrooms. Research has shown that a principal's instructional leadership is second only to teaching among…

  15. Molten Salt Power Tower Cost Model for the System Advisor Model (SAM)

    Energy Technology Data Exchange (ETDEWEB)

    Turchi, C. S.; Heath, G. A.

    2013-02-01

    This report describes a component-based cost model developed for molten-salt power tower solar power plants. The cost model was developed by the National Renewable Energy Laboratory (NREL), using data from several prior studies, including a contracted analysis from WorleyParsons Group, which is included herein as an Appendix. The WorleyParsons' analysis also estimated material composition and mass for the plant to facilitate a life cycle analysis of the molten salt power tower technology. Details of the life cycle assessment have been published elsewhere. The cost model provides a reference plant that interfaces with NREL's System Advisor Model or SAM. The reference plant assumes a nominal 100-MWe (net) power tower running with a nitrate salt heat transfer fluid (HTF). Thermal energy storage is provided by direct storage of the HTF in a two-tank system. The design assumes dry-cooling. The model includes a spreadsheet that interfaces with SAM via the Excel Exchange option in SAM. The spreadsheet allows users to estimate the costs of different-size plants and to take into account changes in commodity prices. This report and the accompanying Excel spreadsheet can be downloaded at https://sam.nrel.gov/cost.

  16. Chair rise capacity and associated factors in older home-care clients.

    Science.gov (United States)

    Tiihonen, Miia; Hartikainen, Sirpa; Nykänen, Irma

    2017-07-01

    The aim of this study was to investigate the ability of older home-care clients to perform the five times chair rise test and associated personal characteristics, nutritional status and functioning. The study sample included 267 home-care clients aged ≥75 years living in Eastern and Central Finland. The home-care clients were interviewed at home by home-care nurses, nutritionists and pharmacists. The collected data contained sociodemographic factors, functional ability (Barthel Index, IADL), cognitive functioning (MMSE), nutritional status (MNA), depressive symptoms (GDS-15), medical diagnoses and drug use. The primary outcome was the ability to perform the five times chair rise test. Fifty-one per cent ( n=135) of the home-care clients were unable to complete the five times chair rise test. Twenty-three per cent ( n=64) of the home-care clients had good chair rise capacity (≤17 seconds). In a multivariate logistic regression analysis, fewer years of education (odds ratio [OR] = 1.11, 95% confidence interval [CI] 1.04-1.18), lower ADL (OR = 1.54, 95% CI 1.34-1.78) and low MNA scores (OR = 1.12, 95% CI 1.04-1.20) and a higher number of co-morbidities (OR = 1.21, 95% CI 1.02-1.43) were associated with inability to complete the five times chair rise test. Poor functional mobility, which was associated with less education, a high number of co-morbidities and poor nutritional status, was common among older home-care clients. To maintain and to prevent further decline in functional mobility, physical training and nutritional services are needed. (NutOrMed, ClinicalTrials.gov Identifier: NCT02214758).

  17. Walking, chair rising, and stair climbing after total knee arthroplasty: patellar resurfacing versus nonresurfacing.

    Science.gov (United States)

    Pollo, F E; Jackson, R W; Koëter, S; Ansari, S; Motley, G S; Rathjen, K W

    2000-01-01

    During the past decade, the technology and design of knee joint prostheses has progressed considerably. However, there is still much controversy on whether resurfacing the patella during routine total knee arthroplasty (TKA) is necessary. This study compares the biomechanics of the lower limb in patients after TKA with and without patellar resurfacing during level walking, stair climbing, and chair rising. Eighteen patients who underwent TKA by two different surgeons using the same prosthesis were studied after full rehabilitation while walking, stair climbing, and chair rising. Patients were divided between those who were resurfaced and those who were not resurfaced. An aged-matched control population was recruited for comparison. The Hospital for Special Surgery Knee Rating Scale was used to gather clinical information. Kinematic and kinetic parameters were collected using a 5-camera Motion Analysis System and an AMTI OR6-5 force platform. For level walking, patients were asked to walk at a self-selected speed down an 8-m walkway. For stair climbing, patients were asked to climb a 4-step staircase without handrail support and for chair rising, patients were asked to rise from a chair that was positioned at the height of their knee joint line. Five trials for each side were recorded for averaging and statistical analysis. Temporal-spatial parameters and kinematic and kinetic variables at the knee joint were tested for significance using the repeated measures analysis of variance (ANOVA). There were no significant differences in the biomechanics of walking, stair climbing, or chair rising between patients after TKA with and without a resurfaced patella.

  18. Effect of a suspension seat support chair on the trunk flexion angle and gluteal pressure during computer work.

    Science.gov (United States)

    Yoo, Won-Gyu

    2015-09-01

    [Purpose] We assessed the effects of a suspension seat support chair on the trunk flexion angle and gluteal pressure during computer work. [Subjects] Ten males were recruited. [Methods] The suspension seat support was developed to prevent abnormal gluteal pressure and a slumped sitting posture during computer work. The gluteal pressure was measured with a TekScan system and the trunk flexion angle was measured with a video camera, to compare the differences between a general chair and the suspension seat support. [Results] The gluteal peak pressures were decreased significantly in the suspension seat support versus the general chair. The trunk flexion angle was also decreased significantly in the suspension seat support compared with the general chair. [Conclusions] This study suggests that the suspension seat support chair contributes to preventing abnormal gluteal pressure and a slumped sitting posture.

  19. Evidence for Smectite Clays from MSL SAM Analyses of Mudstone at Yellowknife Bay, Gale Crater, Mars

    Science.gov (United States)

    McAdam, Amy; Franz, Heather; Mahaffy, Paul R.; Eigenbrode, Jennifer L.; Stern, Jennifer C.; Brunner, Anna; Archer, Paul Douglas; Ming, Douglas W.; Morris, Richard V.; Atreya, Sushil K.

    2013-01-01

    Drilled samples of mudstone from the Sheepbed unit at Yellowknife Bay were analyzed by MSL instruments including the Sample Analysis at Mars (SAM) and Chemistry and Mineralogy (CheMin) instruments in MSL's Analytical Laboratory. CheMin analyses revealed the first in situ X-ray diffraction based evidence of clay minerals on Mars, which are likely trioctahedral smectites (e.g., saponite) and comprise approx 20% of the mudstone sample (e.g., Bristow et al., this meeting). SAM analyses, which heated the mudstone samples to 1000 C and monitored volatiles evolved to perform in situ evolved gas analysis mass spectrometry (EGA-MS), resulted in a H2O trace exhibiting a wide evolution at temperatures clay mineral. Comparison to EGA-MS data collected under SAM-like conditions on a variety of clay mineral reference materials indicate that a trioctahedral smectite, such as saponite, is most consistent with the high temperature H2O evolution observed. There may also be SAM EGA-MS evidence for a small high temperature H2O evolution from scoop samples from the Yellowknife Bay Rocknest sand shadow bedform. As in the mudstone samples, this evolution may indicate the detection of smectite clays, and the idea that minor clays may be present in Rocknest materials that could be expected to be at least partially derived from local sources is reasonable. But, because smectite clays were not definitively observed in CheMin analyses of Rocknest materials, they must be present at much lower abundances than the approx 20% observed in the mudstone samples. This potential detection underscores the complementary nature of the MSL CheMin and SAM instruments for investigations of martian sample mineralogy. Information on the nature of Yellowknife Bay clay minerals may also be available from the detection of H2 evolved during SAM EGA-MS at high temperature. A likely source of at least some of this H2 is H2O evolved from the smectite clays at high temperature, and it is possible these evolutions can

  20. Mechanism elucidation of the radical SAM enzyme spore photoproduct lyase (SPL)

    Science.gov (United States)

    Li, Lei

    2011-01-01

    Spore photoproduct lyase (SPL) repairs a special thymine dimer 5-thyminyl-5,6-dihydrothymine, which is commonly called spore photoproduct or SP at the bacterial early germination phase. SP is the exclusive DNA photo-damage product in bacterial endospores; its generation and swift repair by SPL are responsible for the spores’ extremely high UV resistance. The early in vivo studies suggested that SPL utilizes a direct reversal strategy to repair the SP in the absence of light. The research in the past decade further established SPL as a radical SAM enzyme, which utilizes a tri-cysteine CXXXCXXC motif to harbor a [4Fe-4S] cluster. At the 1+ oxidation state, the cluster provides an electron to the S-adenosylmethionine (SAM), which binds to the cluster in a bidentate manner as the fourth and fifth ligands, to reductively cleave the C-S bond associated with the sulfonium ion in SAM, generating a reactive 5′-deoxyadenosyl (5′-dA) radical. This 5′-dA radical abstracts the proR hydrogen atom from the C6 carbon of SP to initiate the repair process; the resulting SP radical subsequently fragments to generate a putative thymine methyl radical, which accepts a back-donated H atom to yield the repaired TpT. SAM is suggested to be regenerated at the end of each catalytic cycle; and only a catalytic amount of SAM is needed in the SPL reaction. The H atom source for the back donation step is suggested to be a cysteine residue (C141 in B. subtilis SPL), and the H-atom transfer reaction leaves a thiyl radical behind on the protein. This thiyl radical thus must participate in the SAM regeneration process; however how the thiyl radical abstracts an H atom from the 5′-dA to regenerate SAM is unknown. This paper reviews and discusses the history and the latest progress in the mechanistic elucidation of SPL. Despite some recent breakthroughs, more questions are raised in the mechanistic understanding of this intriguing DNA repair enzyme. PMID:22197590

  1. Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria

    DEFF Research Database (Denmark)

    Karminska, K. H.; Purta, E.; Hansen, L .H.

    2010-01-01

    of a 4Fe-4S cluster, a SAM molecule coordinated to the iron-sulfur cluster (SAM1) and a SAM molecule that is the putative methyl group donor (SAM2). All mutations at predicted functional sites affect Cfr activity significantly as assayed by antibiotic susceptibility testing and primer extension analysis....... The investigation has identified essential amino acids and Cfr variants with altered reaction mechanisms and represents a first step towards understanding the structural basis of Cfr activity....

  2. Experimental and computational investigation of graphene/SAMs/n-Si Schottky diodes

    Science.gov (United States)

    Aydin, H.; Bacaksiz, C.; Yagmurcukardes, N.; Karakaya, C.; Mermer, O.; Can, M.; Senger, R. T.; Sahin, H.; Selamet, Y.

    2018-01-01

    We have investigated the effect of two different self-assembled monolayers (SAMs) on electrical characteristics of bilayer graphene (BLG)/n-Si Schottky diodes. Novel 4″bis(diphenylamino)-1, 1‧:3″-terphenyl-5‧ carboxylic acids (TPA) and 4,4-di-9H-carbazol-9-yl-1,1‧:3‧1‧-terphenyl-5‧ carboxylic acid (CAR) aromatic SAMs have been used to modify n-Si surfaces. Cyclic voltammetry (CV) and Kelvin probe force microscopy (KPFM) results have been evaluated to verify the modification of n-Si surface. The current-voltage (I-V) characteristics of bare and SAMs modified devices show rectification behaviour verifying a Schottky junction at the interface. The ideality factors (n) from ln(I)-V dependences were determined as 2.13, 1.96 and 2.07 for BLG/n-Si, BLG/TPA/n-Si and BLG/CAR/n-Si Schottky diodes, respectively. In addition, Schottky barrier height (SBH) and series resistance (Rs) of SAMs modified diodes were decreased compared to bare diode due to the formation of a compatible interface between graphene and Si as well as π-π interaction between aromatic SAMs and graphene. The CAR-based device exhibits better diode characteristic compared to the TPA-based device. Computational simulations show that the BLG/CAR system exhibits smaller energy-level-differences than the BLG/TPA, which supports the experimental findings of a lower Schottky barrier and series resistance in BLG/CAR diode.

  3. Molecular cloning, characterization and expression analysis of the SAMS gene during adventitious root development in IBA-induced tetraploid black locust.

    Directory of Open Access Journals (Sweden)

    Jine Quan

    Full Text Available S-Adenosylmethionine synthetase (SAMS catalyzes the synthesis of S-adenosylmethionine (SAM, a precursor for ethylene and polyamine biosynthesis. Here, we report the isolation of the 1498 bp full-length cDNA sequence encoding tetraploid black locust (Robinia pseudoacacia L. SAMS (TrbSAMS, which contains an open reading frame of 1179 bp encoding 392 amino acids. The amino acid sequence of TrbSAMS has more than 94% sequence identity to SAMSs from other plants, with a closer phylogenetic relationship to SAMSs from legumes than to SAMS from other plants. The TrbSAMS monomer consists of N-terminal, central, and C-terminal domains. Subcellular localization analysis revealed that the TrbSAMS protein localizes mainly to in the cell membrane and cytoplasm of onion epidermal cells and Arabidopsis mesophyll cell protoplasts. Indole-3-butyric acid (IBA-treated cuttings showed higher levels of TrbSAMS transcript than untreated control cuttings during root primordium and adventitious root formation. TrbSAMS and its downstream genes showed differential expression in shoots, leaves, bark, and roots, with the highest expression observed in bark. IBA-treated cuttings also showed higher SAMS activity than control cuttings during root primordium and adventitious root formation. These results indicate that TrbSAMS might play an important role in the regulation of IBA-induced adventitious root development in tetraploid black locust cuttings.

  4. From geometry to algebra and vice versa: Realistic mathematics education principles for analyzing geometry tasks

    Science.gov (United States)

    Jupri, Al

    2017-04-01

    In this article we address how Realistic Mathematics Education (RME) principles, including the intertwinement and the reality principles, are used to analyze geometry tasks. To do so, we carried out three phases of a small-scale study. First we analyzed four geometry problems - considered as tasks inviting the use of problem solving and reasoning skills - theoretically in the light of the RME principles. Second, we tested two problems to 31 undergraduate students of mathematics education program and other two problems to 16 master students of primary mathematics education program. Finally, we analyzed student written work and compared these empirical to the theoretical results. We found that there are discrepancies between what we expected theoretically and what occurred empirically in terms of mathematization and of intertwinement of mathematical concepts from geometry to algebra and vice versa. We conclude that the RME principles provide a fruitful framework for analyzing geometry tasks that, for instance, are intended for assessing student problem solving and reasoning skills.

  5. Being stuck in a vice: The process of coping with severe depression in late life.

    Science.gov (United States)

    Bjørkløf, Guro Hanevold; Kirkevold, Marit; Engedal, Knut; Selbæk, Geir; Helvik, Anne-Sofie

    2015-01-01

    Articles describing older persons' experiences of coping with severe depression are, to our knowledge, lacking. This article is methodologically grounded in phenomenological hermeneutics, inspired by Paul Ricoeur, and applies a descriptive design with in-depth interviews for producing the data. We included 18 older persons, 13 women and 5 men, with a mean age of 77.9 years, depressed to a severe or moderate degree, 1-2 weeks after admission to a hospital for treatment of depression. We found the metaphor "being in a vice" to capture the essence of meaning from the participants' stories, and can be understood as being stuck in an immensely painful existence entirely dominated by depression in late life. This is the first article where coping in older men and women experiencing the most severe phase of depression is explored.

  6. M2 to D2 and vice versa by 3-Lie and Lie bialgebra

    Energy Technology Data Exchange (ETDEWEB)

    Aali-Javanangrouh, M.; Rezaei-Aghdam, A. [Azarbaijan Shahid Madani University, Department of Physics, Faculty of Science, Tabriz (Iran, Islamic Republic of)

    2016-11-15

    Using the concept of a 3-Lie bialgebra, which has recently been defined in arXiv:1604.04475, we construct a Bagger-Lambert-Gustavson (BLG) model for the M2-brane on a Manin triple of a special 3-Lie bialgebra. Then by using the correspondence and the relation between those 3-Lie bialgebra with Lie bialgebra, we reduce this model to an N = (4,4) WZW model (D2-brane), such that its algebraic structure is a Lie bialgebra with one 2-cocycle. In this manner by using the correspondence of the 3-Lie bialgebra and Lie bialgebra (for this special 3-Lie algebra) one can construct the M2-brane from a D2-brane and vice versa. (orig.)

  7. The bronchial response to mannitol is attenuated by a previous methacholine test: but not vice versa

    DEFF Research Database (Denmark)

    Gade, E.; Thomsen, S.F.; Porsbjerg, C.

    2009-01-01

    To examine the airway response to inhaled mannitol performed before or after a methacholine challenge test in a group of asthmatics with different levels of disease. A total of 48 asthmatics, 18-73 years of age, were included in the study. Two pairs of challenges were performed in a random order...... on two separate days >= 24 h apart: either with mannitol performed first on day one, followed >= 1 h by methacholine, and methacholine as the first on day two, followed >= 1 h by mannitol or vice versa. A questionnaire-based interview was performed and lung function, exhaled nitric oxide, skin prick test......, and blood eosinophil count were measured. A total of 44% of the asthmatics used inhaled corticosteroids and 48% were atopic. The airway response to mannitol was attenuated when mannitol was given after methacholine, compared with the response to mannitol when it was given first [log response dose ratio (RDR...

  8. DEMOCRACIES VIRTUES AND VICES VIRTUDES E VÍCIUS DA DEMOCRACIA

    Directory of Open Access Journals (Sweden)

    Helena Esser dos Reis

    2008-04-01

    Full Text Available Democracy can be regarded, following Alexis de Tocquevilles
    thoughts, from two complementary standpoints: the equality standpoint – where equality is understood as a social condition; and the liberty standpoint – understood as a political condition. However, he observes, democracy is not a priori what it should be, denunciating, in this way, the imbalance between equality and liberty, the greater the imbalance as poor are the public virtues. We intend to enroll in a debate involving ethics and politics, by considering vices and virtues inherent to democracy, analyzing Tocqueville´s ideas. We start examining the causes of vice and the possibility of virtue, as Tocqueville sees them, in order to, next, attack the relationship of ethics and politics.A democracia pode ser compreendida, segundo Aléxis de Tocqueville, a partir de duas idéias complementares: a condição social de igualdade e a condição política de liberdade. Entretanto, observa, a democracia não é a priori o que deveria ser, denunciando, deste modo, a existência de um descompasso entre a igualdade e a liberdade que cresce na mesma medida em que esmorecem as virtudes públicas. Visando contribuir com a discussão acerca das relações entre ética e política, pretendo examinar virtudes e vícios inerentes ao Estado democrático, a partir da análise das idéias de Tocqueville. Meu interesse será, em primeiro lugar, compreender
    as causas dos vícios e a possibilidade das virtudes nas democracias, para, então, discutir a relação entre a ética e a política.

  9. Stability of phosphonic self assembled monolayers (SAMs) on cobalt chromium (Co-Cr) alloy under oxidative conditions

    Science.gov (United States)

    Bhure, Rahul; Abdel-Fattah, Tarek M.; Bonner, Carl; Hall, Felicia; Mahapatro, Anil

    2011-04-01

    Cobalt chromium (Co-Cr) alloys have been widely used in the biomedical arena for cardiovascular, orthopedic and dental applications. Surface modification of the alloy allows us to tailor the interfacial properties to address critical challenges of Co-Cr alloy in medical applications. Self assembled monolayers (SAMs) of Octadecylphosphonic acid (ODPA) have been used to form thin films on the oxide layer of the Co-Cr alloy surface by solution deposition technique. The SAMs formed were investigated for their stability to oxidative conditions of ambient laboratory environment over periods of 1, 3, 7 and 14 days. The samples were then characterized for their stability using X-ray Photoelectron Spectroscopy (XPS), Atomic Force Microscopy (AFM) and contact angle measurements. Detailed high energy XPS elemental scans confirmed the presence of the phosphonic monolayer after oxidative exposure which suggested that the SAMs were firmly attached to the oxide layer of Co-Cr alloy. AFM images gave topographical data of the surface and showed islands of SAMs on Co-Cr alloy surface, before and after SAM formation and also over the duration of the oxidative exposure. Contact angle measurements confirmed the hydrophobicity of the surface over 14 days. Thus the SAMs were found to be stable for the duration of the study. These SAMs could be subsequently tailored by modifying the terminal functional groups and could be used for various potential biomedical applications such as drug delivery, biocompatibility and tissue integration.

  10. Evolved Gas Analyses of Sedimentary Materials in Gale Crater, Mars: Results of the Curiosity Rover's Sample Analysis at Mars (SAM) Instrument from Yellowknife Bay to the Stimson Formation

    Science.gov (United States)

    Sutter, B.; McAdam, A. C.; Rampe, E. B.; Ming, D. W.; Mahaffy, P. R.; Navarro-Gonzalez, R.; Stern, J. C.; Eigenbrode, J. L.; Archer, P. D.

    2016-01-01

    The Sample Analysis at Mars (SAM) instrument aboard the Mars Science Laboratory rover has analyzed 10 samples from Gale Crater. All SAM evolved gas analyses have yielded a multitude of volatiles (e.g, H2O, SO2, H2S, CO2, CO, NO, O2, HC1). The objectives of this work are to 1) Characterize the evolved H2O, SO2, CO2, and O2 gas traces of sediments analyzed by SAM through sol 1178, 2) Constrain sediment mineralogy/composition based on SAM evolved gas analysis (SAM-EGA), and 3) Discuss the implications of these results releative to understanding the geochemical history of Gale Crater.

  11. Development of a Virtual Presence Sharing System Using a Telework Chair

    Science.gov (United States)

    Ishii, Yutaka; Watanabe, Tomio

    There has been much discussion on remote communication support for a telework that will enable employees to work at remote offices. We have already developed a remote communication support system via embodied avatars based on users’ behaviors. However, there are various problems associated with an avatar-mediated interaction, particularly with regard to the relation between users and their avatars. In this study, we propose the concept of a presence sharing system Ghatcha [GHost Avatar on a Telework CHAir] in which the users’ embodiment is not indicated by the avatars but by the chairs that suggest the presence of avatars. This system provides the same communication space for the users’ embodiment, thus creating a feeling of working alongside remote workers. Moreover, the effectiveness of the prototype system is confirmed in the experiment.

  12. Key Tenets of Effective Surgery Leadership: Perspectives From the Society of Surgical Chairs Mentorship Sessions.

    Science.gov (United States)

    Rosengart, Todd K; Kent, K Craig; Bland, Kirby I; Britt, L D; Eberlein, Timothy J; Gewertz, Bruce Labe; Hunter, John G; Lillemoe, Keith D; Pellegrini, Carlos A; Schulick, Richard D; Stain, Steven Charles; Weigel, Ronald J

    2016-08-01

    This Special Communication summarizes the key points raised at the Society of Surgical Chairs mentorship panel sessions held at the 2014 and 2015 annual meetings of the society. Highlights of these expert panel discussions include senior chairs' insights into successfully dealing with increasingly complex academic medical organizations and horizontal department management expectations in the context of the arrival of the Millennial Generation into the work force. Three key tenets of effective surgery leadership that arose from these sessions deal with the importance of (1) collaboration and cooperativity, (2) humanized relationships and mentorship, and (3) operational efficiency. Overall, the panel consensus for the future of surgery leadership was optimistic while recognizing that the demands of chairmanship are considerable.

  13. Online Dissemination Strategies of a Canada Research Chair: Overview and Lessons Learned.

    Science.gov (United States)

    Hébert, Jessica; Robitaille, Hubert; Turcotte, Stéphane; Légaré, France

    2017-02-24

    Little is known about the use of online dissemination strategies, such as websites and social media, to increase the visibility and uptake of research. To describe two online dissemination strategies of the Canada Research Chair in Implementation of Shared Decision Making in Primary Care over an eight-year period. Our two sources of online dissemination data were the website of the Canada Research Chair in Implementation of Shared Decision Making in Primary Care and the Chair's Twitter account. We conducted a content analysis of the news section of the website. We extracted website usage statistics using Google Analytics and analyzed indicators such as total number of visits, new and returning visitors, page views per visit, time spent onsite per visit, visitors' country of origin, and most popular pages. From the Chair's Twitter account, we collected the number of tweets, followers, and follows. We consulted Google Scholar to chart the trend in citations of the Chair's articles over the same period. From the website's inception in January 2008 to December 2015, we recorded an average of 7906 visits per year (3809 in 2008; 8874 in 2015), 65.85% of which involved new visitors (5206/7906). The average number of pages viewed per visit was 3.2 and average bounce rate was 57.87% (4575/7906). Visitors spent an average of two minutes and 12 seconds per visit. We computed visits from 162 countries, with the majority from Canada (5910/7906, 74.75%). In order of frequency, the seven most visited pages were: (1) home page with news of publications and grants (24,787 visits), (2) profile of Chairholder (8041 visits), (3) profiles of research team members (6272 visits), (4) list of research team members (4593 visits), (5) inventory of shared decision making (SDM) programs (1856 visits), (6) interprofessional approaches to SDM (1689 visits), and (7) description of Chair activities (1350 visits). From the inception of the Twitter account in April 2011 to November 30, 2016 we

  14. Modifying Ways of Modern Local Furniture Design to The Ming-style Circle Chairs

    Directory of Open Access Journals (Sweden)

    Xue Ruizhu

    2016-01-01

    Full Text Available In recent years, the scales and works for local Chinese original furniture designs have been rapidly increasing. This article elaborated the inner requirement for modern families to local furniture designs. And by comparing circle chairs of “Moreless”, “Fnji”, “pusu”, “Lost&Found” and “LEXTO” with those made in Ming Dynasty, deeply analysis the modifying ways of modern local furniture design to the circle chairs with Ming style, such as tenon structure, matierals and so on. It aimed at increasing peoples’ understanding for local furniture designs, improving peoples’ attention for local original furniture design. Finally, this article supplied reference for the development of the local furniture design.

  15. Neuromuscular responses during the performance of a chair rising exercise in aquatic and dry land

    OpenAIRE

    Cuesta-Vargas, Antonio; Cano Herrera, Carlos

    2012-01-01

    INTRODUCTION: In aquatic physiotherapy programs are used the functional tasks, which are quite important during the activities of daily living. Knowing the degree of muscular activation during the performance of these functional tasks is important for physiotherapists, in order to find out which can be used in each moment (on dry land or in water). AIM: The purpose of the present study was to analyze the neuromuscular responses during the performance of a chair rising (CR) exercise in aqua...

  16. Utilisation du moringa, de la spiruline, de la patate douce à chair ...

    African Journals Online (AJOL)

    Les biscuits peuvent contribuer à améliorer le statut nutritionnel des jeunes enfants. L'effet de l'incorporation du moringa, de la spiruline, de la patate douce à chair orange (PDCO) et d'un complexe minéral et vitaminique (CMV) sur la qualité nutritionnelle des biscuits de sorgho est étudié. Pour ces ingrédients nutritionnels, ...

  17. Active-passive biodynamics of the human trunk when seated on a wobble chair.

    Science.gov (United States)

    Shahvarpour, A; Shirazi-Adl, A; Larivière, C

    2016-04-11

    Unstable sitting on a wobble chair with different balance difficulty levels can be used as an effective tool in exercises as well as evaluation and therapeutic stages of rehabilitation. No data on muscle activity levels and spinal loads are however available to assess its safety compared to other regular daily activities. The goal of this study was to estimate muscle forces and spinal loads in a seated unstable wobble chair task. In vivo 3D kinematics of the trunk and seat collected in an earlier study were used here to drive computational trunk musculoskeletal models of 6 normal and 6 low-back pain subject groups sitting on a wobble chair for a duration of 10s. Results revealed no significant differences between kinematics, muscle forces, spinal loads and force plate reaction forces when comparing these two groups. The estimated muscle forces and spinal loads were moderate though larger than those in a stationary sitting posture. Local spinal forces at the L5-S1 disc varied with time and reached their peaks (1473 N and 1720 N in compression, 691 N and 687 N in posterior-anterior shear and 153 N and 208 N in right-left shear, respectively for healthy and CLBP groups) being much greater relative to those in the stationary sitting posture (means of 12 subjects: 768 N, 284 N and 0 N, respectively). The wobble chair with characteristics considered in this study is found hence safe enough as a therapeutic exercise for both healthy and low-back pain subjects. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Machining variability impacts on the strength of a 'chair-side' CAD-CAM ceramic.

    LENUS (Irish Health Repository)

    Addison, Owen

    2012-08-01

    To develop a novel methodology to generate specimens for bi-axial flexure strength (BFS) determination from a \\'chair-side\\' CAD-CAM feldspathic ceramic with surface defect integrals analogous to the clinical state. The hypotheses tested were: BFS and surface roughness (R(a)) are independent of machining variability introduced by the renewal or deterioration of form-grinding tools and that a post-machining annealing cycle would significantly modify BFS.

  19. Pharmacy practice department chairs' perspectives on part-time faculty members.

    Science.gov (United States)

    Fjortoft, Nancy; Winkler, Susan R; Mai, Thy

    2012-05-10

    To identify the benefits and consequences of having part-time faculty members in departments of pharmacy practice from the department chair's perspective. A stratified purposive sample of 12 pharmacy practice department chairs was selected. Eleven telephone interviews were conducted. Two investigators independently read interview notes and categorized and enumerated responses to determine major themes using content analysis. The investigators jointly reviewed the data and came to consensus on major themes. Benefits of allowing full-time faculty members to reduce their position to part-time included faculty retention and improved individual faculty work/life balance. Consequences of allowing part-time faculty positions included the challenges of managing individual and departmental workloads, the risk of marginalizing part-time faculty members, and the challenges of promotion and tenure issues. All requests to switch to part-time status were faculty-driven and most were approved. There are a variety of benefits and consequences of having part-time faculty in pharmacy practice departments from the chair's perspective. Clear faculty and departmental expectations of part-time faculty members need to be established to ensure optimal success of this working arrangement.

  20. Solar wheel chair; Solar kurumaisu (iryokei no tachiba kara no kokoromi)

    Energy Technology Data Exchange (ETDEWEB)

    Okabe, K. [Gunma Prefectural College of Health Sciences, Gunma (Japan)

    1996-10-27

    Physically handicapped people due to accidents for example have been increasing yearly in number with the increase of the aged, spread of cars, and change in the living environment. Therefore, participation in society by such people as called the weak is indispensable. Under the circumstances, as a means of their participation, a wheel chair as a moving aid was examined from the viewpoint of medical treatment and classified into three categories as follows: (1) for the use of the aged who are healthy but leg muscles are weak, (2) for the use of the invalid incapable of moving a part of the body and (3) for the use in sports by people who are disabled in the lower half of the body but healthy otherwise. In other words, prototypes were made for three kinds of solar wheel chair, for the aged, for the invalid and for sport use by the disabled, with a field test performed for each prototype. The wheel chairs were exhibited in the school, used in welfare facilities and driven by a disabled person who participated in 100km marathon. The users` opinions were favorable stating they were able to drive by themselves the new vehicle utilizing the clean energy and to move around by their own free will. 6 refs., 5 figs.

  1. Chair Design Analysis Of Work To Reduce Musculoskeletal Part 1 Anthropometry Method

    Directory of Open Access Journals (Sweden)

    Nelfiyanti

    2015-08-01

    Full Text Available Refilling of fire extinguishers is a key activity in PT Pinaco Utama Indonesia. In these activities the workers doing the work manually with ergonomic postures that can cause a complaint to the musculoskeletal system. In a preliminary study a questionnaire used Nordic Body Map is used to identify specific problems in parts of the body and using REBA Rapid Entire Body Assessment to determine the level of risk working posture. This preliminary study shows that workers have a lot of complaints on the part of their body with a high level of risk and very high. For that we need a tool that can reduce the complaints of the musculoskeletal system. Tools in the form of work chair. The purpose of this study was to design an ergonomic office chair and is equipped with several features to accommodate the needs and conditions in PT Pinaco Utama Indonesia. The first step of this research is to develop the expectations of the office chair features information then is poured into a design concept. Furthermore this concept is manifested in a more specific design taking into account the anthropometric dimensions of the workers. Making the design and production cost calculation is made to perform a feasibility analysis in this research.

  2. In Vivo Spinal Posture during Upright and Reclined Sitting in an Office Chair

    Directory of Open Access Journals (Sweden)

    Roland Zemp

    2013-01-01

    Full Text Available Increasing numbers of people spend the majority of their working lives seated in an office chair. Musculoskeletal disorders, in particular low back pain, resulting from prolonged static sitting are ubiquitous, but regularly changing sitting position throughout the day is thought to reduce back problems. Nearly all currently available office chairs offer the possibility to alter the backrest reclination angles, but the influence of changing seating positions on the spinal column remains unknown. In an attempt to better understand the potential to adjust or correct spine posture using adjustable seating, five healthy subjects were analysed in an upright and reclined sitting position conducted in an open, upright MRI scanner. The shape of the spine, as described using the vertebral bodies’ coordinates, wedge angles, and curvature angles, showed high inter-subject variability between the two seating positions. The mean lumbar, thoracic, and cervical curvature angles were 29±15°, -29±4°, and 13±8° for the upright and 33±12°, -31±7°, and 7±7° for the reclined sitting positions. Thus, a wide range of seating adaptation is possible through modification of chair posture, and dynamic seating options may therefore provide a key feature in reducing or even preventing back pain caused by prolonged static sitting.

  3. Wide Range Vacuum Pumps for the SAM Instrument on the MSL Curiosity Rover

    Science.gov (United States)

    Sorensen, Paul; Kline-Schoder, Robert; Farley, Rodger

    2014-01-01

    Creare Incorporated and NASA Goddard Space Flight Center developed and space qualified two wide range pumps (WRPs) that were included in the Sample Analysis at Mars (SAM) instrument. This instrument was subsequently integrated into the Mars Science Laboratory (MSL) "Curiosity Rover," launched aboard an Atlas V rocket in 2011, and landed on August 6, 2012, in the Gale Crater on Mars. The pumps have now operated for more than 18 months in the Gale Crater and have been evacuating the key components of the SAM instrument: a quadrupole mass spectrometer, a tunable laser spectrometer, and six gas chromatograph columns. In this paper, we describe the main design challenges and the ways in which they were solved. This includes the custom design of a miniaturized, high-speed motor to drive the turbo drag pump rotor, analysis of rotor dynamics for super critical operation, and bearing/lubricant design/selection.

  4. Carbon tax effects on the poor: a SAM-based approach

    Science.gov (United States)

    Chapa, Joana; Ortega, Araceli

    2017-09-01

    A SAM-based price model for Mexico is developed in order to assess the effects of the carbon tax, which was part of the fiscal reform approved in 2014. The model is formulated based on a social accounting matrix (SAM) that distinguishes households by the official poverty condition and geographical area. The main results are that the sector that includes coke, refined petroleum and nuclear fuel shows the highest price increase due to the direct impact of the carbon tax; in addition, air transport and inland transport are the most affected sectors, in an indirect manner, because both employ inputs from the former sector. Also, it is found that welfare diminishes more in the rural strata than in the urban one. In the urban area, the carbon tax is regressive: the negative impact of carbon tax on family welfare is greater on the poorest families.

  5. Parabolic Trough Reference Plant for Cost Modeling with the Solar Advisor Model (SAM)

    Energy Technology Data Exchange (ETDEWEB)

    Turchi, C.

    2010-07-01

    This report describes a component-based cost model developed for parabolic trough solar power plants. The cost model was developed by the National Renewable Energy Laboratory (NREL), assisted by WorleyParsons Group Inc., for use with NREL's Solar Advisor Model (SAM). This report includes an overview and explanation of the model, two summary contract reports from WorleyParsons, and an Excel spreadsheet for use with SAM. The cost study uses a reference plant with a 100-MWe capacity and six hours of thermal energy storage. Wet-cooling and dry-cooling configurations are considered. The spreadsheet includes capital and operating cost by component to allow users to estimate the impact of changes in component costs.

  6. REPRESENTASI HOMOSEKSUALITAS DI YOUTUBE: (Studi Semiotika pada Video Pernikahan Sam Tsui

    Directory of Open Access Journals (Sweden)

    Lilis Rucirisyanti

    2017-12-01

    Full Text Available Abstract. Social media is instrumental in giving effect to nitizens, good effects or bad effect, then social media can be also represent a person. Diserve social media make it interesting for nitizens. One of social media is Youtube. Many a lot of video at there, strat from tips and trick videos, journey or vacation video, wedding video, and ect. Everyone can publish their video on Youtube. No exception of same sex enthusiast, in this study are homosexual or gay. One of is a wedding video Sam Tsui and Casey Braves. This research is a qualitative research and this research uses semiotcs analysus of Roland Barthes. By doing an analysis of video that have been published by Sam on Youtube, also do document search and literature. The author sees the existence of verbal and non vebal forms of representation from same sex merriage video of men and men.

  7. Sam68 promotes Schwann cell proliferation by enhancing the PI3K/Akt pathway and acts on regeneration after sciatic nerve crush

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Weijie, E-mail: 459586768@qq.com; Liu, Yuxi, E-mail: 924013616@qq.com; Wang, Youhua, E-mail: wyouhua1516@163.com

    2016-05-13

    Sam68 (Src-associated in mitosis of 68 kD), a KH domain RNA-binding protein, is not only important in signaling transduction cascades, but crucial in a variety of cellular processes. Sam68 is reported to be involved in the phospoinositide3-kinase (PI3K) and nuclear factor-kappa B (NF-κB) signaling pathways, and it is closely associated with cell proliferation, RNA metabolism, and tumor progression. However, we know little about the role of Sam68 during peripheral nervous system injury and regeneration. In this study, we investigated the expression of Sam68 and its biological significances in sciatic nerve crush. Interestingly, we found Sam68 had a co-localization with S100 (Schwann cell marker). Moreover, after crush, Sam68 had a spatiotemporal protein expression, which was in parallel with proliferation cell nuclear antigen (PCNA). In vitro, we also observed increased expression of Sam68 during the process of TNF-α-induced Schwann cell proliferation model. Besides, flow cytometry analyses, CCK-8, and EDU were all performed with the purpose of investigating the role of Sam68 in the regulation of Schwann cell proliferation. Even more importantly, we discovered that Sam68 could enhance the phosphorylation of Akt while LY294002 (a PI3K inhibitor) obviously reversed Sam68-induced cell proliferation. Finally, we detected the variance during regeneration progress through the rat walk footprint test. In summary, all these evidences demonstrated that Sam68 might participate in Schwann cell proliferation partially via PI3K/Akt pathway and also regulate regeneration after sciatic nerve crush. -- Highlights: •The dynamic changes and location of Sam68 after sciatic nerve crush. •Sam68 promoted Schwann cell proliferation via PI3K/Akt pathway. •Sam68 modulated functional recovery after sciatic nerve crush.

  8. Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme

    OpenAIRE

    Shisler, Krista A.; Hutcheson, Rachel U.; Horitani, Masaki; Duschene, Kaitlin S.; Crain, Adam V.; Byer, Amanda S.; Shepard, Eric M.; Rasmussen, Ashley; Yang, Jian; Broderick, William E.; Vey, Jessica L.; Drennan, Catherine L.; Hoffman, Brian M.; Broderick, Joan B

    2017-01-01

    Pyruvate formate-lyase activating enzyme (PFL-AE) is a radical S-adenosyl-l-methionine (SAM) enzyme that installs a catalytically essential glycyl radical on pyruvate formate-lyase. We show that PFL-AE binds a catalytically essential monovalent cation at its active site, yet another parallel with B12 enzymes, and we characterize this cation site by a combination of structural, biochemical, and spectroscopic approaches. Refinement of the PFL-AE crystal structure reveals Na+ as the most likely ...

  9. Peran Pimpinan Dalam Meningkatkan Kualitas Pelayanan Di Perpustakaan Fakultas Teknik Universitas Sam Ratulangi Manado

    OpenAIRE

    Kojoh, Fricky F

    2014-01-01

    Ladership role in improving the quality of library services in university engineering faculty Sam Ratulangi. The role of leadership is crucial to a library, The low quality of service in the library, certainly caused by many factors. Fator factors include the low role of leadership, employee performance, interpersonal communication, commitment to employees, the duties and others. Research Objectives How to determine the role of leadership in improving the quality of services at the Library of...

  10. Parabolic Trough Collector Cost Update for the System Advisor Model (SAM)

    Energy Technology Data Exchange (ETDEWEB)

    Kurup, Parthiv [National Renewable Energy Lab. (NREL), Golden, CO (United States); Turchi, Craig S. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    This report updates the baseline cost for parabolic trough solar fields in the United States within NREL's System Advisor Model (SAM). SAM, available at no cost at https://sam.nrel.gov/, is a performance and financial model designed to facilitate decision making for people involved in the renewable energy industry. SAM is the primary tool used by NREL and the U.S. Department of Energy (DOE) for estimating the performance and cost of concentrating solar power (CSP) technologies and projects. The study performed a bottom-up build and cost estimate for two state-of-the-art parabolic trough designs -- the SkyTrough and the Ultimate Trough. The SkyTrough analysis estimated the potential installed cost for a solar field of 1500 SCAs as $170/m2 +/- $6/m2. The investigation found that SkyTrough installed costs were sensitive to factors such as raw aluminum alloy cost and production volume. For example, in the case of the SkyTrough, the installed cost would rise to nearly $210/m2 if the aluminum alloy cost was $1.70/lb instead of $1.03/lb. Accordingly, one must be aware of fluctuations in the relevant commodities markets to track system cost over time. The estimated installed cost for the Ultimate Trough was only slightly higher at $178/m2, which includes an assembly facility of $11.6 million amortized over the required production volume. Considering the size and overall cost of a 700 SCA Ultimate Trough solar field, two parallel production lines in a fully covered assembly facility, each with the specific torque box, module and mirror jigs, would be justified for a full CSP plant.

  11. Hubungan Penggunaan Laptop Dan Fungsi Penglihatan Mahasiswa Angkatan 2011 Fakultas Kedokteran Universitas Sam Ratulangi Manado

    OpenAIRE

    Ningsih, Sri S; Lintong, Fransiska; Rumampuk, Jimmy F

    2015-01-01

    : Nowadays, laptop is very trendy because it can be used anywhere. It is very useful in teaching and learning. This study aimed to determine the relation of the use of laptop and visual function. This was a descriptive study using questionnairre and survey. Respondents were students Faculty of Medicine, University of Sam Ratulangi batch 2011. Based on duration, time interval, occurence of complaints, and laptop lighting, the bivariate analysis showed a P value >0.05. Conclusion: There was no ...

  12. Efektivitas Kelompok Diskusi Tutorial Problem Based Learning di Fakultas Kedokteran Universitas Sam Ratulangi

    OpenAIRE

    Pioh, Virgin Enjel; Mewo, Yanti; Berhimpon, Siemona

    2016-01-01

    : The Faculty of Medicine, Sam Ratulangi University has applied the Problem Based Learning (PBL) method in which the tutorial group discussion is the center in this learning method. The purpose of PBL is to improve the students' problem solving skill which is essential for the students who are going to be professional medical practitioners in the future. Therefore, the effectiveness of the tutorial group discussion of PBL must be implemented in order to achieve the learning goalsThe cognitive...

  13. New solutions for large scale functional tests in the WLCG infrastructure with SAM/Nagios: the experiments experience

    CERN Document Server

    Andreeva, J; Di Girolamo, A; Kakkar, A; Litmaath, M; Magini, N; Negri, G; Ramachandran, S; Roiser, S; Saiz, P; Saiz Santos, M D; Sarkar, B; Schovancova, J; Sciabà, A; Wakankar, A

    2012-01-01

    Since several years the LHC experiments rely on the WLCG Service Availability Monitoring framework (SAM) to run functional tests on their distributed computing systems. The SAM tests have become an essential tool to measure the reliability of the Grid infrastructure and to ensure reliable computing operations, both for the sites and the experiments. Recently the old SAM framework was replaced with a completely new system based on Nagios and ActiveMQ to better support the transition to EGI and to its more distributed infrastructure support model and to implement several scalability and functionality enhancements. This required all LHC experiments and the WLCG support teams to migrate their tests, to acquire expertise on the new system, to validate the new availability and reliability computations and to adopt new visualisation tools. In this contribution we describe in detail the current state of the art of functional testing in WLCG: how the experiments use the new SAM/Nagios framework, the advanced functiona...

  14. SAMSVM: A tool for misalignment filtration of SAM-format sequences with support vector machine.

    Science.gov (United States)

    Yang, Jianfeng; Ding, Xiaofan; Sun, Xing; Tsang, Shui-Ying; Xue, Hong

    2015-12-01

    Sequence alignment/map (SAM) formatted sequences [Li H, Handsaker B, Wysoker A et al., Bioinformatics 25(16):2078-2079, 2009.] have taken on a main role in bioinformatics since the development of massive parallel sequencing. However, because misalignment of sequences poses a significant problem in analysis of sequencing data that could lead to false positives in variant calling, the exclusion of misaligned reads is a necessity in analysis. In this regard, the multiple features of SAM-formatted sequences can be treated as vectors in a multi-dimension space to allow the application of a support vector machine (SVM). Applying the LIBSVM tools developed by Chang and Lin [Chang C-C, Lin C-J, ACM Trans Intell Syst Technol 2:1-27, 2011.] as a simple interface for support vector classification, the SAMSVM package has been developed in this study to enable misalignment filtration of SAM-formatted sequences. Cross-validation between two simulated datasets processed with SAMSVM yielded accuracies that ranged from 0.89 to 0.97 with F-scores ranging from 0.77 to 0.94 in 14 groups characterized by different mutation rates from 0.001 to 0.1, indicating that the model built using SAMSVM was accurate in misalignment detection. Application of SAMSVM to actual sequencing data resulted in filtration of misaligned reads and correction of variant calling.

  15. Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN.

    Directory of Open Access Journals (Sweden)

    Christina M Fitzsimmons

    Full Text Available RlmN, a bacterial radical SAM methylating enzyme, has the unusual ability to modify two distinct types of RNA: 23S rRNA and tRNA. In rRNA, RlmN installs a methyl group at the C2 position of A2503 of 23S rRNA, while in tRNA the modification occurs at nucleotide A37, immediately adjacent to the anticodon triplet. Intriguingly, only a subset of tRNAs that contain an adenosine at position 37 are substrates for RlmN, suggesting that the enzyme carefully probes the highly conserved tRNA fold and sequence features to identify its targets. Over the past several years, multiple studies have addressed rRNA modification by RlmN, while relatively few investigations have focused on the ability of this enzyme to modify tRNAs. In this study, we utilized in vitro transcribed tRNAs as model substrates to interrogate RNA recognition by RlmN. Using chimeras and point mutations, we probed how the structure and sequence of RNA influences methylation, identifying position 38 of tRNAs as a critical determinant of substrate recognition. We further demonstrate that, analogous to previous mechanistic studies with fragments of 23S rRNA, tRNA methylation requirements are consistent with radical SAM reactivity. Together, our findings provide detailed insight into tRNA recognition by a radical SAM methylating enzyme.

  16. Integration, Validation, and Application of a PV Snow Coverage Model in SAM

    Energy Technology Data Exchange (ETDEWEB)

    Ryberg, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Freeman, Janine [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    Due to the increasing deployment of PV systems in snowy climates, there is significant interest in a method capable of estimating PV losses resulting from snow coverage that has been verified for a wide variety of system designs and locations. A scattering of independent snow coverage models have been developed over the last 15 years; however, there has been very little effort spent on verifying these models beyond the system design and location on which they were based. Moreover, none of the major PV modeling software products have incorporated any of these models into their workflow. In response to this deficiency, we have integrated the methodology of the snow model developed in the paper by Marion et al. [1] into the National Renewable Energy Laboratory's (NREL) System Advisor Model (SAM). In this work we describe how the snow model is implemented in SAM and discuss our demonstration of the model's effectiveness at reducing error in annual estimations for two PV arrays. Following this, we use this new functionality in conjunction with a long term historical dataset to estimate average snow losses across the United States for a typical PV system design. The open availability of the snow loss estimation capability in SAM to the PV modeling community, coupled with our results of the nation-wide study, will better equip the industry to accurately estimate PV energy production in areas affected by snowfall.

  17. Formation and characterization of low resistivity sub-100 nm copper films deposited by electroless on SAM

    Energy Technology Data Exchange (ETDEWEB)

    Asher, T. [Dept. of Physical Electronics, Faculty of Engineering, Tel-Aviv University, Ramat-Aviv 69978, Tel-Aviv (Israel)], E-mail: tamaras3@tau.ac.il; Inberg, A.; Glickman, E.; Fishelson, N.; Shacham-Diamand, Y. [Dept. of Physical Electronics, Faculty of Engineering, Tel-Aviv University, Ramat-Aviv 69978, Tel-Aviv (Israel)

    2009-10-30

    Thin Cu films of microelectronic quality and low electrical resistivity were created by electroless deposition (ELD) onto SiO{sub 2} surface modified first with self-assembled monolayer (SAM) of 3-aminopropyltrimethoxysilane (APTMS) and activated then by 5 nm gold nano-particles (AuNPs). The presence of highly oriented amino-terminated SAM was revealed by XPS and ToF-SIMS analyses. The Cu films were deposited in boron- and phosphorous-free tartrate/formaldehyde electrolyte. Controlling the deposition rate via the solution pH permitted a minimum value in resistivity {rho}. XPS depth profile revealed that diffusion of Cu into SiO{sub 2} modified by APTMS did not take place after annealing at 220 deg. C, 4 h. Moreover, annealing resulted in the drop of electrical resistivity to {rho} = 4 {+-} 0.4 {mu}{omega} cm for the films with the thickness of 35-100 nm. This value of {rho} is several times smaller than those reported in literature for sub-100 nm Cu films deposited by electroless on different SAMs. It is speculated that nano-scale porosity and corrugated structure observed by HRTEM and AFM in the ELD Cu films contribute to the resistivity. The obtained results demonstrate a viable route for formation of low resistivity, sub-100 nm Cu films on dielectrics for microelectronic application.

  18. Integration, Validation, and Application of a PV Snow Coverage Model in SAM

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, Janine M. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ryberg, David Severin [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-08-01

    Due to the increasing deployment of PV systems in snowy climates, there is significant interest in a method capable of estimating PV losses resulting from snow coverage that has been verified for a variety of system designs and locations. Many independent snow coverage models have been developed over the last 15 years; however, there has been very little effort verifying these models beyond the system designs and locations on which they were based. Moreover, major PV modeling software products have not yet incorporated any of these models into their workflows. In response to this deficiency, we have integrated the methodology of the snow model developed in the paper by Marion et al. (2013) into the National Renewable Energy Laboratory's (NREL) System Advisor Model (SAM). In this work, we describe how the snow model is implemented in SAM and we discuss our demonstration of the model's effectiveness at reducing error in annual estimations for three PV arrays. Next, we use this new functionality in conjunction with a long term historical data set to estimate average snow losses across the United States for two typical PV system designs. The open availability of the snow loss estimation capability in SAM to the PV modeling community, coupled with our results of the nationwide study, will better equip the industry to accurately estimate PV energy production in areas affected by snowfall.

  19. Microtribological and electrochemical corrosion behaviors of polydopamine coating on APTS-SAM modified Si substrate

    Energy Technology Data Exchange (ETDEWEB)

    Ou Junfei [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100080 (China); Wang Jinqing, E-mail: jqwang@lzb.ac.cn [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Liu Sheng [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100080 (China); Zhou Jinfang [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Ren Sili, E-mail: slren@lzb.ac.cn [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yang Shengrong [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

    2009-11-15

    A polydopamine coating (coded as PDAc) was prepared successfully on a Si substrate through a two-step process. Briefly, to improve the adhesion of PDAc on the Si substrate, a self-assembled monolayer of 3-aminopropyl triethoxysilane (coded as APTS-SAM) was firstly generated on the bare Si wafer. Thereafter, the PDAc with different thickness was fabricated through the chemical adsorption and autopolymerization of the dopamine hydrochloride on the APTS-SAM coated Si substrate. The formation of PDAc on the APTS-SAM modified Si substrate was proved by the characterizations of contact angle measurement, attenuated total reflectance Fourier transform infrared (ATR-FTIR) analysis, and X-ray photoelectron spectroscope (XPS), etc. The ellipsometric thickness measurement and atomic force microscopy (AFM) image analysis showed that the PDAc became thicker and rougher with the deposition time prolongation. Microtribological study showed that the thickness and roughness of the PDAc played a significant role in the tribological properties. In comparison with the bare Si substrate, the PDAc with thinner thickness possessed lower friction and was anticipated to be used as protecting coating in the field of boundary lubrication. The electrochemical corrosion behaviors of the prepared PDAc were investigated using the electrochemical station and a low corrosion current density was revealed, implying that the PDAc had good anti-corrosion capability and might find potential applications in the field of corrosion resistance.

  20. Microtribological and electrochemical corrosion behaviors of polydopamine coating on APTS-SAM modified Si substrate

    Science.gov (United States)

    Ou, Junfei; Wang, Jinqing; Liu, Sheng; Zhou, Jinfang; Ren, Sili; Yang, Shengrong

    2009-11-01

    A polydopamine coating (coded as PDAc) was prepared successfully on a Si substrate through a two-step process. Briefly, to improve the adhesion of PDAc on the Si substrate, a self-assembled monolayer of 3-aminopropyl triethoxysilane (coded as APTS-SAM) was firstly generated on the bare Si wafer. Thereafter, the PDAc with different thickness was fabricated through the chemical adsorption and autopolymerization of the dopamine hydrochloride on the APTS-SAM coated Si substrate. The formation of PDAc on the APTS-SAM modified Si substrate was proved by the characterizations of contact angle measurement, attenuated total reflectance Fourier transform infrared (ATR-FTIR) analysis, and X-ray photoelectron spectroscope (XPS), etc. The ellipsometric thickness measurement and atomic force microscopy (AFM) image analysis showed that the PDAc became thicker and rougher with the deposition time prolongation. Microtribological study showed that the thickness and roughness of the PDAc played a significant role in the tribological properties. In comparison with the bare Si substrate, the PDAc with thinner thickness possessed lower friction and was anticipated to be used as protecting coating in the field of boundary lubrication. The electrochemical corrosion behaviors of the prepared PDAc were investigated using the electrochemical station and a low corrosion current density was revealed, implying that the PDAc had good anti-corrosion capability and might find potential applications in the field of corrosion resistance.

  1. Photoresponsive SAMs on gold fabricated from azobenzene-functionalised asparagusic acid derivatives.

    Science.gov (United States)

    Siemeling, Ulrich; Bruhn, Clemens; Bretthauer, Frauke; Borg, Marta; Träger, Frank; Vogel, Florian; Azzam, Waleed; Badin, Mihaela; Strunskus, Thomas; Wöll, Christof

    2009-10-28

    We have prepared a range of azobenzene derivatives equipped with an asparagusic acid-based 1,2-dithiolane headgroup suitable for chemisorption on solid gold substrates. The formation of self-assembled monolayers (SAMs) of the amide cyclo-S2C3H5-4-C(O)NH-p-C6H4-N=N-Ph (1) and the ester cyclo-S2C3H5-4-C(O)O-p-C6H4-N=N-Ph (2) on gold was monitored in situ and in real time by optical second harmonic generation (SHG). The structure and composition of these SAMs was investigated by a range of ex situ methods, viz. ellipsometry, X-ray photoelectron spectroscopy (XPS), near-edge X-ray absorption fine structure (NEXAFS) spectroscopy and Fourier transform infrared reflection absorption spectroscopy (FTIRRAS). Reversible, but moderate, photoswitchability was observed for these one-component SAMs by ellipsometry and dynamic contact angle measurements. Use of a second 1,2-dithiolane component for lateral dilution of the photoactive terminal groups resulted in a much more pronounced photoresponse.

  2. Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure.

    Science.gov (United States)

    Ding, Chengli; Wu, Zhifei; Huang, Lei; Wang, Yajie; Xue, Jie; Chen, Si; Deng, Zixin; Wang, Lianrong; Song, Zhiyin; Chen, Shi

    2015-11-04

    The inner mitochondrial membrane (IMM) invaginates to form cristae and the maintenance of cristae depends on the mitochondrial contact site (MICOS) complex. Mitofilin and CHCHD6, which physically interact, are two components of the MICOS. In this study, we performed immunoprecipitation experiments with Mitofilin and CHCHD6 antibodies and identified a complex containing Mitofilin, Sam50, and CHCHD 3 and 6. Using transcription activator-like effector nucleases (TALENs), we generated knockdown/knockout clones of Mitofilin and CHCHD6. Transmission electron microscopy (TEM) revealed that vesicle-like cristae morphology appeared in cell lines lacking Mitofilin, and mitochondria exhibited lower cristae density in CHCHD6-knockout cells. Immunoblot analysis showed that knockdown of Mitofilin, but not knockout of CHCHD6, affected their binding partners that control cristae morphology. We also demonstrated that Mitofilin and CHCHD6 directly interacted with Sam50. Additionally, we observed that Mitofilin-knockdown cells showed decreased mitochondrial membrane potential (ΔΨm) and intracellular ATP content, which were minimally affected in CHCHD6-knockout cells. Taken together, we conclude that the integrity of MICOS and its efficient interaction with Sam50 are indispensable for cristae organization, which is relevant to mitochondrial function.

  3. A magnesium-induced triplex pre-organizes the SAM-II riboswitch.

    Directory of Open Access Journals (Sweden)

    Susmita Roy

    2017-03-01

    Full Text Available Our 13C- and 1H-chemical exchange saturation transfer (CEST experiments previously revealed a dynamic exchange between partially closed and open conformations of the SAM-II riboswitch in the absence of ligand. Here, all-atom structure-based molecular simulations, with the electrostatic effects of Manning counter-ion condensation and explicit magnesium ions are employed to calculate the folding free energy landscape of the SAM-II riboswitch. We use this analysis to predict that magnesium ions remodel the landscape, shifting the equilibrium away from the extended, partially unfolded state towards a compact, pre-organized conformation that resembles the ligand-bound state. Our CEST and SAXS experiments, at different magnesium ion concentrations, quantitatively confirm our simulation results, demonstrating that magnesium ions induce collapse and pre-organization. Agreement between theory and experiment bolsters microscopic interpretation of our simulations, which shows that triplex formation between helix P2b and loop L1 is highly sensitive to magnesium and plays a key role in pre-organization. Pre-organization of the SAM-II riboswitch allows rapid detection of ligand with high selectivity, which is important for biological function.

  4. Regulation of Ack1 localization and activity by the amino-terminal SAM domain

    Directory of Open Access Journals (Sweden)

    Brown Deborah A

    2010-10-01

    Full Text Available Abstract Background The mechanisms that regulate the activity of the nonreceptor tyrosine kinase Ack1 (activated Cdc42-associated kinase are poorly understood. The amino-terminal region of Ack1 is predicted to contain a sterile alpha motif (SAM domain. SAM domains share a common fold and mediate protein-protein interactions in a wide variety of proteins. Here, we addressed the importance of the Ack1 SAM domain in kinase activity. Results We used immunofluorescence and Western blotting to show that Ack1 deletion mutants lacking the N-terminus displayed significantly reduced autophosphorylation in cells. A minimal construct comprising the N-terminus and kinase domain (NKD was autophosphorylated, while the kinase domain alone (KD was not. When expressed in mammalian cells, NKD localized to the plasma membrane, while KD showed a more diffuse cytosolic localization. Co-immunoprecipitation experiments showed a stronger interaction between full length Ack1 and NKD than between full length Ack1 and KD, indicating that the N-terminus was important for Ack1 dimerization. Increasing the local concentration of purified Ack1 kinase domain at the surface of lipid vesicles stimulated autophosphorylation and catalytic activity, consistent with a requirement for dimerization and trans-phosphorylation for activity. Conclusions Collectively, the data suggest that the N-terminus of Ack1 promotes membrane localization and dimerization to allow for autophosphorylation.

  5. Nuclear Protein Sam68 Interacts with the Enterovirus 71 Internal Ribosome Entry Site and Positively Regulates Viral Protein Translation.

    Science.gov (United States)

    Zhang, Hua; Song, Lei; Cong, Haolong; Tien, Po

    2015-10-01

    Enterovirus 71 (EV71) recruits various cellular factors to assist in the replication and translation of its genome. Identification of the host factors involved in the EV71 life cycle not only will enable a better understanding of the infection mechanism but also has the potential to be of use in the development of antiviral therapeutics. In this study, we demonstrated that the cellular factor 68-kDa Src-associated protein in mitosis (Sam68) acts as an internal ribosome entry site (IRES) trans-acting factor (ITAF) that binds specifically to the EV71 5' untranslated region (5'UTR). Interaction sites in both the viral IRES (stem-loops IV and V) and the heterogeneous nuclear ribonucleoprotein K homology (KH) domain of Sam68 protein were further mapped using an electrophoretic mobility shift assay (EMSA) and biotin RNA pulldown assay. More importantly, dual-luciferase (firefly) reporter analysis suggested that overexpression of Sam68 positively regulated IRES-dependent translation of virus proteins. In contrast, both IRES activity and viral protein translation significantly decreased in Sam68 knockdown cells compared with the negative-control cells treated with short hairpin RNA (shRNA). However, downregulation of Sam68 did not have a significant inhibitory effect on the accumulation of the EV71 genome. Moreover, Sam68 was redistributed from the nucleus to the cytoplasm and interacts with cellular factors, such as poly(rC)-binding protein 2 (PCBP2) and poly(A)-binding protein (PABP), during EV71 infection. The cytoplasmic relocalization of Sam68 in EV71-infected cells may be involved in the enhancement of EV71 IRES-mediated translation. Since Sam68 is known to be a RNA-binding protein, these results provide direct evidence that Sam68 is a novel ITAF that interacts with EV71 IRES and positively regulates viral protein translation. The nuclear protein Sam68 is found as an additional new host factor that interacts with the EV71 IRES during infection and could potentially

  6. Converting chair-like transition states into zig-zag projections: A method of drawing stereochemical structures

    National Research Council Canada - National Science Library

    Hussaini, Syed R

    2014-01-01

    A short and easy method for the conversion of chair-like transition states into zig-zag projections using planar cyclohexane structures, and also the concepts of change of bond in the plane and group...

  7. A radiolucent chair for sitting-posture radiographs in non-ambulatory children: use in biplanar digital slot-scanning

    Energy Technology Data Exchange (ETDEWEB)

    Bouloussa, Houssam; Dubory, Arnaud; Bachy, Manon [Universite Pierre et Marie Curie-Paris 6, Armand Trousseau Hospital, Department of Pediatric Orthopaedics, Paris Cedex 12 (France); Seiler, Catherine [Groupe Lagarrigue, Clichy (France); Morel, Baptiste [Universite Pierre et Marie Curie-Paris 6, Armand Trousseau Hospital, Department of Pediatric Imaging, Paris (France); Vialle, Raphael [Universite Pierre et Marie Curie-Paris 6, Armand Trousseau Hospital, Department of Pediatric Orthopaedics, Paris Cedex 12 (France); Armand Trousseau Hospital, The MAMUTH Hospital-University Department for Innovative Therapies in Musculoskeletal Diseases, Paris (France)

    2015-11-15

    EOS imaging (EOS System; EOS imaging, Paris, France) enables fast 2-D/3-D imaging of children in standing load-bearing position. Non-ambulatory children with neuromuscular scoliosis need evaluation of their spinal balance while in a normal daily position. We designed a customized chair fitting the EOS patient-area dimensions to obtain images in natural sitting postures. The chair is a 360 rotating orthopaedic chair made of fully radiolucent polyethylene and equipped with an adjustable headrest and three-point belts. Out of 41 consecutive patients, 36 (88%, 95% confidence interval 74-96%) had successful imaging. In most patients with severe neuromuscular trunk deformities, the EOS system combined with our chair was useful for assessing preoperative trunk collapse, pelvic obliquity and postoperative corrections in all planes. This specific device changed our daily practice for the assessment of spinal deformities in non-ambulatory patients. (orig.)

  8. Inhibition of HIV-1 gene expression by Sam68ΔC: multiple targets but a common mechanism?

    Directory of Open Access Journals (Sweden)

    Cochrane Alan

    2009-03-01

    Full Text Available Abstract Two recent publications have explored the mechanisms by which a mutant of the host protein Sam68 blocks HIV-1 structural protein synthesis and expands its activity to encompass Nef. Although the two studies propose different mechanisms for the responses observed, it is possible that a common activity is responsible. Understanding how this Sam68 mutant discriminates among the multiple viral mRNAs promises to reveal unique properties of HIV-1 RNA metabolism.

  9. Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

    DEFF Research Database (Denmark)

    Xiong, Kai; Zhou, Yan; Hyttel, Poul

    2016-01-01

    Human fibroblasts were engineered to express the CRISPR-based synergistic activation mediator (SAM) complex: dCas9-VP64 and MS2-P65-HSF1. Two induced pluripotent stem cells (iPSCs) clones expressing SAM were established by transducing these fibroblasts with lentivirus expressing OCT4, SOX2, KLF4...... a novel, useful tool to investigate genetic regulation of stem cell proliferation and differentiation through CRISPR-mediated activation of endogenous genes....

  10. Suicide assessment and management initiative (SAM): evaluating the implementation and uptake of suicide prevention activities in a healthcare setting.

    OpenAIRE

    Ishmael, Kiera Suzanne

    2010-01-01

    Suicide is one of the leading causes of death among Canadian men and women from adolescence to middle age and is strongly associated with mental illness. BC Mental Health and Addiction Services has developed Suicide Assessment and Management (SAM) Guidelines to identify safety risks within its client populations. Rigourous evaluation of the SAM Guidelines Initiative is essential to determine the impact of the intervention. This paper describes the literature review and logic model for the SA...

  11. Evidence for Perchlorates and the Origin of Chlorinated Hydrocarbons Detected by SAM at the Rocknest Aeolian Deposit in Gale Crater

    Science.gov (United States)

    Glavin, Daniel P.; Freissinet, Caroline; Miller, Kristen E.; Eigenbrode, Jennifer L.; Brunner, Anna E.; Buch, Arnaud; Sutter, Brad; Archer, P. Douglas, Jr.; Atreya, Sushil K.; Brinckerhoff, William B.; hide

    2013-01-01

    A single scoop of the Rocknest aeolian deposit was sieved (less than 150 micrometers), and four separate sample portions, each with a mass of approximately 50 mg, were delivered to individual cups inside the Sample Analysis at Mars (SAM) instrument by the Mars Science Laboratory rover's sample acquisition system. The samples were analyzed separately by the SAM pyrolysis evolved gas and gas chromatograph mass spectrometer analysis modes. Several chlorinated hydrocarbons including chloromethane, dichloromethane, trichloromethane, a chloromethylpropene, and chlorobenzene were identified by SAM above background levels with abundances of approximately 0.01 to 2.3 nmol. The evolution of the chloromethanes observed during pyrolysis is coincident with the increase in O2 released from the Rocknest sample and the decomposition of a product of N-methyl-N-(tert-butyldimethylsilyl)-trifluoroacetamide (MTBSTFA), a chemical whose vapors were released from a derivatization cup inside SAM. The best candidate for the oxychlorine compounds in Rocknest is a hydrated calcium perchlorate (Ca(ClO4)2·nH2O), based on the temperature release of O2 that correlates with the release of the chlorinated hydrocarbons measured by SAM, although other chlorine-bearing phases are being considered. Laboratory analog experiments suggest that the reaction of Martian chlorine from perchlorate decomposition with terrestrial organic carbon from MTBSTFA during pyrolysis can explain the presence of three chloromethanes and a chloromethylpropene detected by SAM. Chlorobenzene may be attributed to reactions of Martian chlorine released during pyrolysis with terrestrial benzene or toluene derived from 2,6-diphenylphenylene oxide (Tenax) on the SAM hydrocarbon trap. At this time we do not have definitive evidence to support a nonterrestrial carbon source for these chlorinated hydrocarbons, nor do we exclude the possibility that future SAM analyses will reveal the presence of organic compounds native to the

  12. Controllably Designed "Vice-Electrode" Interlayers Harvesting High Performance Lithium Sulfur Batteries.

    Science.gov (United States)

    Hao, Youchen; Xiong, Dongbin; Liu, Wen; Fan, Linlin; Li, Dejun; Li, Xifei

    2017-11-22

    An interlayer has been regarded as a promising mediator to prolong the life span of lithium sulfur batteries because its excellent absorbability to soluble polysulfide efficiently hinders the shuttle effect. Herein, we designed various interlayers and understand the working mechanism of an interlayer for lithium sulfur batteries in detail. It was found that the electrochemical performance of a S electrode for an interlayer located in cathode side is superior to the pristine one without interlayers. Surprisingly, the performance of the S electrode for an interlayer located in anode side is poorer than that of pristine one. For comparison, glass fibers were also studied as a nonconductive interlayer for lithium sulfur batteries. Unlike the two interlayers above, these nonconductive interlayer did displays significant capacity fading because polysulfides were adsorbed onto insulated interlayer. Thus, the nonconductive interlayer function as a "dead zone" upon cycling. Based on our findings, it was for the first time proposed that a controllably optimized interlayer, with electrical conductivity as well as the absorbability of polysulfides, may function as a "vice-electrode" of the anode or cathode upon cycling. Therefore, the cathodic conductive interlayer can enhance lithium sulfur battery performance, and the anodic conductive interlayer may be helpful for the rational design of 3D networks for the protection of lithium metal.

  13. Prevalence of Celiac Disease in Children with Autoimmune Hepatitis and vice versa.

    Science.gov (United States)

    Najafi, Mehri; Sadjadei, Nooshin; Eftekhari, Kambiz; Khodadad, Ahmad; Motamed, Farzaneh; Fallahi, Gholam-Hossain; Farahmand, Fatemeh

    2014-12-01

    Celiac disease is an autoimmune disorder in which the risk of autoimmune liver disease is high. Autoimmune hepatitis is a chronic and progressive entity and the risk of its being associated with other autoimmune disorders such as celiac disease is high also. The aim of this study was to determine the prevalence of celiac disease in patients with autoimmune hepatitis and vice versa. In a cross-sectional study children with autoimmune hepatitis underwent serological screening and endoscopy for celiac disease. In patients with celiac disease, serum aminotransferases were measured and, if abnormal, autoantibodies related to autoimmune hepatitis were checked and needle liver biopsy was performed. Of the 96 patients, 64 had autoimmune hepatitis and 32 celiac disease. Among patients with autoimmune hepatitis only three (4.7%) were compatible with celiac disease. In the group of patients with celiac disease, autoimmune hepatitis was confirmed in four (12.5%) cases. We consider important to state that 3.1% of this group had celiac hepatitis. Autoimmune liver disease is sometimes associated with latent celiac disease. Serological screening for celiac disease should be routinely done in patients with abnormal serum aminotransferases, particularly those with chronic liver disease. On the other hand, celiac disease is often accompanied by other autoimmune diseases, including autoimmune hepatitis.

  14. Supplementary Material for: A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein

    KAUST Repository

    Smirnova, Ekaterina

    2016-01-01

    Abstract Background CASKIN2 is a homolog of CASKIN1, a scaffolding protein that participates in a signaling network with CASK (calcium/calmodulin-dependent serine kinase). Despite a high level of homology between CASKIN2 and CASKIN1, CASKIN2 cannot bind CASK due to the absence of a CASK Interaction Domain and consequently, may have evolved undiscovered structural and functional distinctions. Results We demonstrate that the crystal structure of the Sterile Alpha Motif (SAM) domain tandem (SAM1-SAM2) oligomer from CASKIN2 is different than CASKIN1, with the minimal repeating unit being a dimer, rather than a monomer. Analytical ultracentrifugation sedimentation velocity methods revealed differences in monomer/dimer equilibria across a range of concentrations and ionic strengths for the wild type CASKIN2 SAM tandem and a structure-directed double mutant that could not oligomerize. Further distinguishing CASKIN2 from CASKIN1, EGFP-tagged SAM tandem proteins expressed in Neuro2a cells produced punctae that were distinct both in shape and size. Conclusions This study illustrates a new way in which neuronal SAM domains can assemble into large macromolecular assemblies that might concentrate and amplify synaptic responses.

  15. The Porter-Whitesides Discrepancy: Revisiting Odd-Even Effects in Wetting Properties of n-Alkanethiolate SAMs

    Directory of Open Access Journals (Sweden)

    Zhengjia Wang

    2015-12-01

    Full Text Available This review discusses the Porter-Whitesides discrepancy in wetting properties of n-alkanethiolate self-assembled monolayers (SAMs. About 25 years ago, Whitesides and coworker failed to observe any odd-even effect in wetting, however, Porter and his coworker did, albeit in select cases. Most previous studies agreed with Whitesides’ results, suggesting the absence of the odd-even effect in hydrophobicity of n-alkanethiolate SAMs. Recent reports have, however, found the odd-even effect in hydrophobicity of n-alkanethiolate SAMs on smooth substrates, indicating that hydrophobicity, and analogous interfacial properties, of n-alkanethiolate SAMs significantly depends on the properties of substrate. Unfortunately, the Whitesides and Porter papers do not report on the quality of the surfaces used. Based on recent work, we inferred that the original discrepancy between Whitesides and Porter can be attributed to the quality of the surface. Odd-even effect of SAMs in charge transport, capacitance, friction, and SAM structure are also discussed in this review to inform the general discussion. The discrepancy between Porter's group and Whitesides’ group could be due to surface roughness, morphology, oxidation, and adventitious contaminants.

  16. The Effect of Role Ambiguity and Role Conflict on Performance of Vice Principals: The Mediating Role of Burnout

    Science.gov (United States)

    Celik, Kazim

    2013-01-01

    Problem Statement: Role ambiguity and role conflict are considered issues that affect performance and lead to burnout. While numerous studies have analyzed role ambiguity or role conflict in relation to burnout or performance, few studies have studied all of these issues together. Since vice principals are expected to carry out a variety of…

  17. Turning Music Catalogues into Archives of Musical Scores – or Vice Versa: Music Archives and Catalogues Based on MEI XML

    DEFF Research Database (Denmark)

    Geertinger, Axel Teich

    2014-01-01

    metadata and fully-featured scores may be a way of overcoming some of these limitations and at the same time include catalogue data in the score and vice versa. The Music Encoding Initiative (MEI) offers a framework for such an approach based on XML files. The article discusses pros and cons...

  18. Selection Criteria, Skill Sets and Competencies: What Is Their Role in the Appointment of Vice-Chancellors in Australian Universities?

    Science.gov (United States)

    O'Meara, Bernard; Petzall, Stanley

    2009-01-01

    Purpose: The research presented here attempts to identify and analyse the reported selection criteria used in the appointment of Australian vice-chancellors (VCs) and to contrast this with the selection criteria actually used. Design/methodology/approach: Contemporary research into the nature, role and purpose of section criteria in appointment…

  19. The Lived Experiences of Vice Presidents for Student Affairs: A Study Exploring How Social Identity Impacts Leadership Approach

    Science.gov (United States)

    Jones, David E.

    2016-01-01

    This study aimed to both draw awareness and increase understanding of how lived experiences across race, gender and sexual orientation social identities impact the leadership approach of Vice Presidents for Student Affairs. As the student demographic becomes increasingly more diverse on college and university campuses, higher education leaders…

  20. The Seismic Aftershock Monitoring System (SAMS) for OSI - Experiences from IFE14

    Science.gov (United States)

    Gestermann, Nicolai; Sick, Benjamin; Häge, Martin; Blake, Thomas; Labak, Peter; Joswig, Manfred

    2016-04-01

    An on-site inspection (OSI) is the third of four elements of the verification regime of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). The sole purpose of an OSI is to confirm whether a nuclear weapon test explosion or any other nuclear explosion has been carried out in violation of the treaty and to gather any facts which might assist in identifying any possible violator. It thus constitutes the final verification measure under the CTBT if all other available measures are not able to confirm the nature of a suspicious event. The Provisional Technical Secretariat (PTS) carried out the Integrated Field Exercise 2014 (IFE14) in the Dead Sea Area of Jordan from 3 November to 9. December 2014. It was a fictitious OSI whose aim was to test the inspection capabilities in an integrated manner. The technologies allowed during an OSI are listed in the Treaty. The aim of the Seismic Aftershock Monitoring System (SAMS) is to detect and localize aftershocks of low magnitudes of the triggering event or collapses of underground cavities. The locations of these events are expected in the vicinity of a possible previous explosion and help to narrow down the search area within an inspection area (IA) of an OSI. The success of SAMS depends on the main elements, hardware, software, deployment strategy, the search logic and not least the effective use of personnel. All elements of SAMS were tested and improved during the Built-Up Exercises (BUE) which took place in Austria and Hungary. IFE14 provided more realistic climatic and hazardous terrain conditions with limited resources. Significant variations in topography of the IA of IFE14 in the mountainous Dead Sea Area of Jordan led to considerable challenges which were not expected from experiences encountered during BUE. The SAMS uses mini arrays with an aperture of about 100 meters and with a total of 4 elements. The station network deployed during IFE14 and results of the data analysis will be presented. Possible aftershocks of

  1. Can Air Seat Cushions and Ball Chairs Improved Classroom Behaviors of Students with Autism Spectrum Disorder: A Single Subject Study

    Directory of Open Access Journals (Sweden)

    Nader Matin Sadr

    2015-06-01

    Full Text Available Background: Classroom behaviorsare disturbed in autistic students because of their repetitive, restlessness, and disruptive behaviors. This study aimed to examine the impacts of sitting on a ball, cushion, and/or common chair on classroom behavior of four students with Autism Spectrum Disorder (ASD. Methods: Four children with Autism participated in this single-subject study. Students’ behaviors were video recorded in three phases: Sitting on their common chairs during phase A, air-sit cushioned in phase B, and ball chairs in phase C. Sitting times and on-task/off-task behaviors were quantified by momentary time sampling (every 10 seconds and compared during different phases for important changes. Social validity was taken by the teacher at the end of the research as well. Results: The findings demonstrated increases in on-task and in-seat behaviors in four students when seated on air sit cushioned chairs. Despite rises of ontask behaviors for all students, only two of the students showed enhanced inseat behaviors when seated on therapy balls. Social validity findings indicated that the teacher preferred the use of the balls and air-cushioned chairs for her students. Conclusion: Therapy balls/cushioned chairs for students with ASD may facilitate in-seat and on-task behavior.

  2. Laparoscopic retroperitoneal partial nephrectomy using an ergonomic chair: demonstration of technique and matched-pair analysis.

    Science.gov (United States)

    Rassweiler, Jens J; Klein, Jan; Tschada, Alexandra; Gözen, Ali Serdar

    2017-02-01

    To present the technique and long-term results of retroperitoneal laparoscopic partial nephrectomy (LPN), focusing on the impact of an ergonomic platform. Between January 2000 and May 2016, 287 patients (193 men, 94 women) underwent LPN performed by four surgeons. The median (range) patient age was 59 (19-85) years, tumour size 3.1 (1-9) cm and PADUA score 7.3 (6-12). Access was retroperitoneal in 235 cases (82%). Since October 2010, we have used the ETHOS™ chair (ETHOS™ , Seattle, WA, USA) during excision of the tumour in 130 patients (45.3%). A total of 51 tumours (17.7%) were excised without ischaemia and 226 (78.7%) under warm ischaemia, with clamping of the renal artery using an enucleo-resection technique. We suture the resection bed and perform renorrhaphy using a barbed-suture pre-loaded with absorbable LAPRA-TY™ clips (Ethicon, Somerville, NJ, USA). The impact of the ETHOS chair was examined using a matched-pair analysis (66 with ETHOS chair vs 67 without ETHOS chair). The median (range) operating time was 146 (60-325) min, the median (range) estimated blood loss was 99 (10-3 000) mL and the mean (range) warm ischaemia time (WIT) was 17.1 (7-47) min. Histology showed 240 (83.6%) renal cell carcinomas (RCCs) and 46 (15.9%) benign tumours. The cumulative overall disease-free survival rate after a median (range) follow-up of 84 (3-155) months was 100% for 203 pT1 RCCs and local recurrence was observed in one patient (0.4%), who was managed by radical nephrectomy. There were two conversions (0.7%) to open surgery, both to hand-assisted laparoscopy. Perirenal haematoma was observed in 13 patients (4.5%). A total of 20 patients (6.9%) required transfusions (2-11 units). We observed five urine leaks (1.7%) requiring prolonged drainage. The median (range) length of hospital stay was 5 (3-24) days. Three patients developed arteriovenous fistulas, which were successfully occluded by superselective embolization (1.0%). Use of the ETHOS chair resulted in shorter

  3. A pilot investigation of emotion-focused two-chair dialogue intervention for self-criticism.

    Science.gov (United States)

    Shahar, Ben; Carlin, Erica R; Engle, David E; Hegde, Jayanta; Szepsenwol, Ohad; Arkowitz, Hal

    2012-01-01

    Self-criticism plays a key role in many psychological disorders and predicts poor outcome in psychotherapy. Yet, psychotherapy research directly targeting self-critical processes is limited. In this pilot study, we examined the efficacy of an emotion-focused intervention, the two-chair dialogue task, on self-criticism, self-compassion and the ability to self-reassure in times of stress, as well as on depressive and anxiety symptoms among nine self-critical clients. Results showed that the intervention was associated with significant increases in self-compassion and self-reassuring, and significant reductions in self-criticism, depressive symptoms and anxiety symptoms. Effect sizes were medium to large, with most clients exhibiting low and non-clinical levels of symptomatology at the end of therapy, and maintaining gains over a 6-month follow-up period. Although preliminary, these finding suggest that emotion-focused chair work might be a promising intervention addressing self-criticism. Self-criticism is an important process in a variety of clinical disorders and predicts poor outcome in brief therapy for depression. Yet, little is known about how self-criticism can be effectively addressed in psychological treatment. Practitioners can benefit from increasing their awareness of self-critical processes in their clinical work, and from directly working with emotions in addressing self-criticisim. Emotion-focused two-chair dialogue intervention can be effective in reducing self-criticism, increasing self-compassion, and decreasing depressive and anxiety symptoms, and these improvements are largely maintained six months after therapy. Copyright © 2011 John Wiley & Sons, Ltd.

  4. Fracture strengths of chair-side-generated veneers cemented with glass fibers.

    Science.gov (United States)

    Turkaslan, S; Bagis, B; Akan, E; Mutluay, M M; Vallittu, P K

    2015-01-01

    CAD/CAM (computer-aided design and computer-aided manufacturing) systems have refreshed the idea of chair-side production of restorations, but the fracture of ceramic veneers remains a problem. Cementation with glass fibers may improve the fracture strengths and affect the failure modes of CAD/CAM-generated ceramic veneers. Therefore, this study compared the fracture strengths of ceramic veneers produced at chair side and cemented with or without glass fibers with those of composite veneers. Thirty intact mandibular incisors were randomly divided into three groups ( n = 10) and treated with CAD/CAM-fabricated veneers cemented with dual-cure composite resin luting cement (CRLC; Group 1), CAD/CAM-fabricated veneers cemented with a glass fiber network (GFN) and dual-cure CRLC (Group 2), and a direct particulate filler composite veneer constructed utilizing fiber and a restorative composite resin (Group 3). The specimens were tested with a universal testing machine after thermal cycling treatment. The loads at the start of fracture were the lowest for traditionally fabricated composite veneers and higher for CAD/CAM-generated. Veneers cemented either without or with the GFN. The failure initiation loads (N) for the veneers were 798.92 for Group 1, 836.27 for Group 2, and 585.93 for Group 3. The predominant failure mode is adhesive failure between the laminates and teeth for Group 1, cohesive failure in the luting layer for Group 2, and cohesive laminate failure for Group 3, which showed chipping and small fractures. Ceramic material is a reliable alternative for veneer construction at chair side. Fibers at the cementation interface may improve the clinical longevity and provide higher fracture strength values.

  5. Finishing and polishing of the ceromer material Targis. Lab-side and chair-side methods.

    Science.gov (United States)

    Behr, M; Rosentritt, M; Leibrock, A; Schneider-Feyrer, S; Handel, G

    1999-01-01

    The aim of the study was to check four lab-side and four chair-side methods for finishing and polishing the ceromer material Targis. Eighty bar-shaped specimens (20 mm x 10 mm x 2 mm) of Vectris were produced; 72 were covered with a 2 mm (thickness) layer of the Ceromer Targis and eight samples with the composite Tetric. All specimens were ground plane parallel with 320 Silicium carbide grit sandpaper in order to start with the same level of roughness. Then the specimens were finished and polished using the following methods: (1) Artglass toolkit, (2) pumice-stone and brushes/linen brush and polishing paste P3, (3) Robinson brush/Ivoclar Universal paste and wool brush, (4) Silicone wheel and rag wheel, (5) Shofu Rainbow set, (6) Sof-Lex discs, (7) Vivadent Politip set and (8) Nupro-pastes and brushes. The surface roughness was determined with a profilometer. The arithmetical roughness value Ra was calculated. From each group one specimen was randomly chosen and sputtered with gold in order to observe the surface with a scanning electron microscope to evaluate its smoothness. The methods were ranked as followed: 2, 3 and 5 with the lowest roughness, then 8, 6, 7, 4, 1. The best ranked chair-side method (5) and the best ranked lab-side methods (2, 3) did not differ significantly between the Ra values. No difference was observed between the composite Tetric and the ceromer Targis when these materials were polished using the same method. the lab-side-methods 2 and 3 and the chair-side-method 5 can be recommended for finishing and polishing the new ceromer material Targis.

  6. The endocrine surgery job market: a survey of fellows, department chairs, and surgery recruiters.

    Science.gov (United States)

    Shin, Joyce J; Milas, Mira; Mitchell, Jamie; Berber, Eren; Gutnick, Jesse; Siperstein, Allan

    2013-01-01

    Fifty endocrine surgery (ES) fellows have completed their training since the American Association of Endocrine Surgeons initiated a formal match process in 2007. This study was designed to better understand the job prospects of current and future endocrine surgeons and to evaluate the evolution of ES practices nationwide. Three surveys were conducted of former fellows, surgery department chairs, and surgery recruiters. Of former fellows, 90% are working in academic centers and 10% in private practice. Average number of job interviews was 3.1 and job offers was 2.2. Eighty-eight percent have a practice that attends to ≥50% ES cases, and 45% practice entirely ES. Ninety-eight percent are satisfied with their job. Subjectively, 57% believe that there are not enough job opportunities for young endocrine surgeons, and 50% believe that there are too many ES fellowships. Department chair survey showed that the average number of endocrine surgeons in their department increased from 1.3 to 2.2 in the past decade. A recognized ES section exists in 49% of centers, and 39% of chairs feel that they will need to recruit another endocrine surgeon in the next 2 years. Only 3 of 10 recruiters were familiar with ES, and all hadjob opportunities to sustain currently trained endocrine surgeons. This contrasts with their subjective belief of limited job prospects. This information can guide the optimal number of fellowship positions and alerts the American Association of Endocrine Surgeons to the opportunity to promote the creation of formal ES sections. Copyright © 2013 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  7. Utilizing Chair Massage to Address One Woman's Health in Rural Ghana West Africa: a Case Report.

    Science.gov (United States)

    Meryanos, Cathy J

    2016-12-01

    There is limited access to health care in rural Ghana and virtually no rehabilitative services available. This situation presents a unique opportunity to utilize chair massage in addressing women's health in rural Ghana, particularly when it comes to muscle pain and fatigue from heavy labor. The objective of this case report is to determine the results of chair massage as a strategy to reduce neck, shoulder, and back pain, while increasing range of motion. The patient is a 63-year-old Ghanaian female, who was struck by a public transport van while carrying a 30-50 pound load on her head, two years prior. The accident resulted in a broken right humerus and soft tissue pain. A traditional medicine practitioner set the bone, however there was no post-accident rehabilitation available. At the time of referral, she presented complaints of shoulder, elbow, and wrist pain. In addition, she was unable to raise her right hand to her mouth for food intake. The results of this case report include an increase in range of motion, as well as elimination of pain in the right shoulder, elbow, and hand. Visual assessments showed an approximate increase of ROM within the ranges of 45-65 degrees in the right arm, as well as 10-15 degrees in 4th and 5th fingers. There was also a decrease in muscle hypertonicity in the thoracic and cervical areas, and a profound increase in quality of life for the patient. This case report illustrates how therapeutic chair massage was utilized to address a common health concern for one woman in rural Ghana. It also demonstrates that pre-existing musculoskeletal disorders and pain may be eliminated with massage intervention. Massage therapy may be important to ameliorating certain types of health problems in remote rural villages in low income countries.

  8. THE 30-S CHAIR STAND TEST AND HABITUAL MOBILITY PREDICT REHABILITATION NEEDS AFTER ACUTE ADMISSION

    DEFF Research Database (Denmark)

    Hansen Bruun, Inge; Nørgaard, Birgitte; Maribo, Thomas

    2016-01-01

    Introduction: One month after admission to emergency department (ED) a fifth of the elderly patients have a low physical ability and therefore a need for rehabilitation. Early identification of these patients is difficult and has so far been based on self-reported information, a challenge...... as elderly might be confused or unrealistic about their physical abilities. The 30-s Chair Stand Test (30s-CST) has not been validated in ED, but is used at community level for this purpose. The De Morton Mobility Index (DEMMI) has been validated for acute patients. Our study evaluated if a 30s-CST-score ≤8...... with habitual mobility....

  9. Comparison of two chair-side tests for enumeration of Mutans Streptococci in saliva

    DEFF Research Database (Denmark)

    Twetman, Lisa; Twetman, Svante

    2014-01-01

    , referred to a maxillofacial hospital clinic with a caries history. Stimulated whole saliva samples were collected and the number of MS was assessed with the Dentocult-SM Strip Mutans (DSM) and the Saliva-Check Mutans (SCM). The outcome was compared with conventional anaerobic laboratory cultivation......AIM: To compare the prevalence and levels of salivary Mutans Streptococci (MS) assessed with two commercial chair-side methods based on culture growth or monoclonal antibodies, respectively. MATERIAL AND METHODS: The study group consisted of a convenience sample of 89 adults, 23-72 years of age...

  10. Chairs and chiefs of plastic surgery: is it an insider job?

    Science.gov (United States)

    Tanna, Neil; Levine, Steven M; Broer, P Niclas; Reavey, Patrick L; Weichman, Katie E; Roostaeian, Jason; Andrews, Brian T; Lerman, Oren Z; Saadeh, Pierre B; Levine, Jamie P

    2013-07-01

    There is no more important decision an academic Plastic Surgery Department or Division can make than naming a chair or chief. Externally recruited leadership brings fresh perspectives and connections. Critics, however, argue that they lack the in-depth knowledge of the institution's culture and history that may be needed to succeed. The ability and skill of an internal candidate is already known and can increase the odds of that person's success in the leadership position. Finally, external recruitment can be a more costly process. Ultimately, the decision is really a litmus test for a Plastic Surgery program. The authors aim to evaluate factors influencing ascent in Plastic Surgery leadership, including training history, internal promotion, and external recruiting. All Plastic Surgery residency programs accredited by the Accreditation Council for Graduate Medical Education were noted (n = 71). Academic departmental chairs or divisional chiefs of these residency programs were identified at the time of study design (October 1, 2011). For each chair or chief, gender, training history, and faculty appointment immediately prior to the current leadership position was recorded. There were 71 academic chairs or chiefs of Plastic Surgery residency programs at the time of data collection. The majority (62%) had done fellowship training following Plastic Surgery residency. Fellowships included hand (43%), craniofacial (29%), microsurgery (18%), and other types (10%). The majority (73%) of leaders were internal hires (P < 0.01), having faculty appointments at their institutions prior to promotion. However, only a fraction (22%) of these internal hires had done Plastic Surgery residency or fellowship training at that institution (P < 0.01). External recruits consisted of 27% of all 71 academic hires (P < 0.01). Many factors influence the decision to recruit leadership from internally or to hire an external candidate. These include the time to fill the position, program culture

  11. THE 30-S CHAIR STAND TEST AND HABITUAL MOBILITY PREDICT REHABILITATION NEEDS AFTER ACUTE ADMISSION

    DEFF Research Database (Denmark)

    Hansen Bruun, Inge; Nørgaard, Birgitte; Backer Mogensen, Christian

    2016-01-01

    were included if oriented in time and place, able to sit on a chair and have a 30s-CST–score ≤ 8. Baseline data were collected within the first 48 hours of admission and the 30s-CST again one month after admission. All risk factors are identified in the literature. The 30s-CST is used at community...... ability among the elderly is important both in terms of their independence, but also from an economic perspective. Furthermore, the study reveals a reveals a tool, which can be used by physiotherapists in an emergency department. Key words: elderly, rehabilitation, screenings tools Funding...

  12. Greater auricular nerve neuropraxia with beach chair positioning during shoulder surgery.

    Science.gov (United States)

    Ng, Albert K H; Page, Richard S

    2010-04-01

    Neuropraxia of the greater auricular nerve is an uncommon complication of shoulder surgery, with the patient in the beach chair position. The greater auricular nerve, a superficial branch of the cervical plexus, is vulnerable to neuropraxia due to its superficial anatomical location. In this case series, we present three cases of neuropraxia associated with direct compression by a horseshoe headrest, used in routine positioning for uncomplicated shoulder surgery. We outline the risk of using devices of this nature and discourage the use of similar headrest devices due to the potential complications in headrest devices that exert pressure on the posterior auricular area to maintain head position during surgery.

  13. Can mentors prevent and reduce burnout in new chairs of departments of obstetrics and gynecology: results from a prospective, randomized pilot study.

    Science.gov (United States)

    Gabbe, Steven G; Webb, Lynn E; Moore, Donald E; Mandel, Lynn S; Melville, Jennifer L; Spickard, W Anderson

    2008-06-01

    This study assessed burnout in new chairs of obstetrics and gynecology and whether mentoring by experienced chairs would prevent or reduce burnout. We performed a year-long prospective, randomized trial. Questionnaires were sent to new chairs to obtain demographic information and to identify need for mentoring and level of burnout. Fourteen chairs in the intervention group selected a mentor; 13 chairs served as controls. After 1 year, questionnaires were completed to determine stress and burnout and the impact of mentoring. Financial issues were the major stressors. New chairs identified human resources, finances, and relationships with school leaders as areas of greatest need for mentoring. Few chairs exhibited burnout. No differences were observed in burnout at the start of the study or after 1 year in the study groups. Mentors and new chairs found the mentoring relationship difficult to establish and maintain. Long-distance mentoring by experienced chairs did not alter burnout in new chairs of obstetrics and gynecology. Local mentors appear to be more effective.

  14. Advancing Women’s Health and Women’s Leadership With Endowed Chairs in Women’s Health

    Science.gov (United States)

    Carnes, Molly; Johnson, Paula; Klein, Wendy; Jenkins, Marjorie; Merz, C. Noel Bairey

    2017-01-01

    Gender-based bias and conflation of gender and status are root causes of disparities in women’s health care and the slow advancement of women to leadership in academic medicine. More than a quarter of women physicians train in internal medicine (IM) and its subspecialties, and women physicians almost exclusively constitute the women’s health focus within IM. Thus, IM has considerable opportunity to develop women leaders in academic medicine and promote women’s health equity. To probe whether holding an endowed chair—which confers status—in women’s health may be an effective way to advance both women leaders in academic medicine and women’s health, the authors explored the current status of endowed chairs in women’s health in IM. They found that the number of these endowed chairs in North America increased from 7 in 2013 to 19 in 2015, and all were held by women. The perceptions of incumbents and other women’s health leaders supported the premise that an endowed chair in women’s health would increase women’s leadership, the institutional stature of women’s health, and activities in women’s health research, education, and clinical care. Going forward, it will be important to explore why not all recipients perceived that the endowed chair enhanced their own academic leadership, whether providing women’s health leaders with fundraising expertise fosters future success in increasing the number of women’s health endowed chairs, and how the conflation of gender and status play out (e.g., salary differences between endowed chairs) as the number of endowed chairs in women’s health increases. PMID:27759706

  15. Loving Sam.

    Science.gov (United States)

    Lasky, Kathryn

    1998-01-01

    Describes how the author came to love Mark Twain's writings, taught "Huckleberry Finn" and other of Twain's writings to a ninth-grade class in a Hasidic Jewish Academy, and learned to really love Samuel Clemens. Describes how this love inspired the author to write two books celebrating what she has valued most in 40 years of reading Mark…

  16. SAM] FORUM

    African Journals Online (AJOL)

    Iararnillo-Ayerbe F, Vallejo—Contreras ]. Frequency and clinical and dermatoscopic features of volar and ungual pigmented melanocytic lesions: a study in school children of Manizales,. Colombia. Peaiatr Dernzatol 2004; 21: 218-222. 18. Ragnarsson-Olding BK. Primary malignant melanoma of the vulva — an aggressive ...

  17. SAMS--a systems architecture for developing intelligent health information systems.

    Science.gov (United States)

    Yılmaz, Özgün; Erdur, Rıza Cenk; Türksever, Mustafa

    2013-12-01

    In this paper, SAMS, a novel health information system architecture for developing intelligent health information systems is proposed and also some strategies for developing such systems are discussed. The systems fulfilling this architecture will be able to store electronic health records of the patients using OWL ontologies, share patient records among different hospitals and provide physicians expertise to assist them in making decisions. The system is intelligent because it is rule-based, makes use of rule-based reasoning and has the ability to learn and evolve itself. The learning capability is provided by extracting rules from previously given decisions by the physicians and then adding the extracted rules to the system. The proposed system is novel and original in all of these aspects. As a case study, a system is implemented conforming to SAMS architecture for use by dentists in the dental domain. The use of the developed system is described with a scenario. For evaluation, the developed dental information system will be used and tried by a group of dentists. The development of this system proves the applicability of SAMS architecture. By getting decision support from a system derived from this architecture, the cognitive gap between experienced and inexperienced physicians can be compensated. Thus, patient satisfaction can be achieved, inexperienced physicians are supported in decision making and the personnel can improve their knowledge. A physician can diagnose a case, which he/she has never diagnosed before, using this system. With the help of this system, it will be possible to store general domain knowledge in this system and the personnel's need to medical guideline documents will be reduced.

  18. Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters.

    Directory of Open Access Journals (Sweden)

    Kiera Murphy

    Full Text Available Thuricin CD is a two-component bacteriocin produced by Bacillus thuringiensis that kills a wide range of clinically significant Clostridium difficile. This bacteriocin has recently been characterized and consists of two distinct peptides, Trnβ and Trnα, which both possess 3 intrapeptide sulphur to α-carbon bridges and act synergistically. Indeed, thuricin CD and subtilosin A are the only antimicrobials known to possess these unusual structures and are known as the sactibiotics (sulplur to alpha carbon-containing antibiotics. Analysis of the thuricin CD-associated gene cluster revealed the presence of genes encoding two highly unusual SAM proteins (TrnC and TrnD which are proposed to be responsible for these unusual post-translational modifications. On the basis of the frequently high conservation among enzymes responsible for the post-translational modification of specific antimicrobials, we performed an in silico screen for novel thuricin CD-like gene clusters using the TrnC and TrnD radical SAM proteins as driver sequences to perform an initial homology search against the complete non-redundant database. Fifteen novel thuricin CD-like gene clusters were identified, based on the presence of TrnC and TrnD homologues in the context of neighbouring genes encoding potential bacteriocin structural peptides. Moreover, metagenomic analysis revealed that TrnC or TrnD homologs are present in a variety of metagenomic environments, suggesting a widespread distribution of thuricin-like operons in a variety of environments. In-silico analysis of radical SAM proteins is sufficient to identify novel putative sactibiotic clusters.

  19. Postmodernism and Language in Sam Shepard's True West and Tooth of Crime

    Directory of Open Access Journals (Sweden)

    Bahar Mehrabi

    2012-09-01

    Full Text Available Sam Shepard has gained a reputation as one of America's foremost living playwrights. In over forty plays, Shepard has broken down traditional notions of dramaturgy in combining both modernist notions of the absurd and familiar icons from the American cultural landscape with an energy tinged by anarchy and violence. Moreover, Shepard has been considered by many critics as a postmodern dramatist. Hassan (1987 piles up a lengthy list of artists from various disciplines whose names epitomize postmodernism for him. The playwrights are: Samuel Beckett, Eugene Ionesco, Harold Pinter and only Sam Shepard and August Wilson from America. One characteristic of postmodern literature in general, is a focus on the instability of meaning and the inadequacy of language to completely and accurately represent truth, along with an irony and playfulness in the treatment of linguistic constructs. In other words, there is a questioning of language as a medium of perception and communication. Language can name the pain but it can’t be the pain; language cannot reach the actual individual feeling. Language is not strong enough to convey the intense emotion.  In postmodern poetics, there is a paradigmatic shift from the idea that language is transparent to the disclosure of its physicality, its intimacy, its obdurate persistence, and its paradoxical fragility. Thus, language is an insufficient means for transforming the ideas that exist in one's mind. The aim of the present article would be to present the ways in which the dramatic language of Sam Shepard, as a postmodern drama, demonstrates inadequacy of language in communication. In order to reach this goal, however, a number of his early dramas will be brought under scrutiny with regard to their language and style from the postmodern point of view.

  20. PhnJ – A novel radical SAM enzyme from the C–P lyase complex

    Directory of Open Access Journals (Sweden)

    Siddhesh S. Kamat

    2015-03-01

    Full Text Available PhnJ from the C–P lyase complex catalyzes the cleavage of the carbon–phosphorus bond in ribose-1-phosphonate-5-phosphate (PRPn to produce methane and ribose-1,2-cyclic-phosphate-5-phosphate (PRcP. This protein is a novel radical SAM enzyme that uses glycyl and thiyl radicals as reactive intermediates in the proposed reaction mechanism. The overall reaction is initiated with the reductive cleavage of S-adenosylmethionine (SAM by a reduced [4Fe–4S]1+-cluster to form an Ado-CH2∙ radical intermediate. This intermediate abstracts the proR hydrogen from Gly-32 of PhnJ to form Ado-CH3 and a glycyl radical. In the next step, there is hydrogen atom transfer from Cys-272 to the Gly-32 radical to generate a thiyl radical. The thiyl radical attacks the phosphorus center of the substrate, PRPn, to form a transient thiophosphonate radical intermediate. This intermediate collapses via homolytic C–P bond cleavage and hydrogen atom transfer from the proS hydrogen of Gly-32 to produce a thiophosphate intermediate, methane, and a radical intermediate at Gly-32. The final product, PRcP, is formed by nucleophilic attack of the C2-hydroxyl on the transient thiophosphate intermediate. This reaction regenerates the free thiol group of Cys-272. After hydrogen atom transfer from Cys-272 to the Gly-32 radical, the entire process is repeated with another substrate molecule without the use of another molecule of SAM or involvement from the [4Fe–4S]-cluster again.

  1. Systematic substrate adoption methodology (SAM) for future flexible, generic pharmaceutical production processes

    DEFF Research Database (Denmark)

    Singh, Ravendra; Godfrey, Andy; Gregertsen, Björn

    2013-01-01

    The discovery of an effective and safe pharmaceutical product is based on success in clinical trials. Often, several candidate compounds targeting the same disease area are tested in order to identify the most efficacious products. This involves the manufacture of small quantities of compounds...... methodology (SAM) for a series of substrates with similar molecular functionality has been developed. The objective is to achieve “flexible, fast and future” pharmaceutical production processes by adapting a generic modular process template. Application of the methodology is illustrated through a case study...... from the pharmaceutical industry. Use of computer-aided methods and tools as part of the methodology is also highlighted....

  2. A uniquely Canadian military moment: Sam Hughes and the No. 7 General Hospital, 1915-1916.

    Science.gov (United States)

    Coombs, Howard G

    2017-08-01

    Universities across Canada actively supported the call to arms in 1914, and Queen's University in Kingston, Ontario, was no different. Though a myriad of units composed of Queen's faculty and students were created, the university perceived the military hospital raised by the school's medical faculty to be among its most vital contributions to the First World War. This commentary describes the engagement of the No. 7 General Hospital with the Minister of Militia, Sam Hughes, which has become an almost unknown footnote to its illustrious story. This commentary has an Appendix, available at canjsurg.ca.

  3. Anodic Behavior of SAM2X5 Material Applied as Amorphous Coatings

    Energy Technology Data Exchange (ETDEWEB)

    Hailey, P D; Farmer, J C; Day, S D; Rebak, R B

    2007-08-10

    Iron-based amorphous alloys are desirable industrial materials since they are highly resistant to corrosion and possess enhanced hardness for wear resistance. The amorphous materials can be produced from the melt as powder and later spray deposited as coatings on large engineering structures. As a laboratory experiment, SAM2X5 powder was coated on electrochemical specimens of 304SS for testing. Results show that the coated specimens did not perform satisfactorily during the laboratory testing. This is because of partial devitrification during the deposition of the powder on the small specimen substrates.

  4. Jean-Martin Charcot and his vibratory chair for Parkinson disease.

    Science.gov (United States)

    Goetz, Christopher G

    2009-08-11

    Vibration therapy is currently used in diverse medical specialties ranging from orthopedics to urology to sports medicine. The celebrated 19th-century neurologist, J.-M. Charcot, used vibratory therapy to treat Parkinson disease (PD). This study analyzed printed writings by Charcot and other writers on vibratory therapy and accessed unpublished notes from the Salpêtrière Hospital, Paris. Charcot lectured on several occasions on vibratory therapy and its neurologic applications. He developed a vibration chair for patients with PD after he observed that patients were more comfortable and slept better after a train or carriage ride. He replicated this experience by having patients undergo daily 30-minute sessions in the automated vibratory chair (fauteuil trépidant). His junior colleague, Gilles de la Tourette, extended these observations and developed a helmet that vibrated the head on the premise that the brain responded directly to the pulsations. Although after Charcot's death vibratory therapy was not widely pursued, vibratory appliances are reemerging in 21st century medicine and can be retested using adaptations of Charcot's neurologic protocols.

  5. [THE CHAIR OF BIRTHS: A RESOURCE COMPANION OF VERTICALITY IN CHILDBIRTH].

    Science.gov (United States)

    Mosquera Pan, Lucía; Onandia Garate, Maialen; Luces Largo, Ana María; Bouza, Eva Tizón

    2015-06-01

    In primitive cultures, women chose to give birth in upright positions such as squatting or sitting, because these positions stimulate a physiological birth. In this way, in order to make easier the delivery support tools such as birthing chair (BC) are discovered. Later, with the medicalization of childbirth, the lithotomy position was introduced as standard practice, with the aim of promoting comfort to the birth attendant. Currently, this position is still prevalent in the hospital environment. The World Health Organization recommendations, stresses the importance of providing impartial information on birthing positions to women, so that she will decide how to give birth without professional influence as a limiting factor in maternal posture. The aim of this review is to make known the utility of the BC, the advantages and disadvantages associated with it, to make it an available resource in vertical childbirth. The BC is a low rise seat horseshoe shaped stable and sturdy structure, and sitting in the chair women acquire squatting position, considered the most natural. The BC is considered a useful tool for childbirth upright. Giving birth using the BC seems to be protective against episiotomies and Kristeller maneuver, provides comfort and empowerment of women and helps them to have a more positive birth experience.

  6. Design and Testing of Low Cost Chair with Round Mortise and Tenon Joints

    Directory of Open Access Journals (Sweden)

    Jaroslav Začal

    2016-01-01

    Full Text Available The present paper focuses on construction of school seats for developing countries from locally available resources using the local industry and low-end technology. Aim of the work is experimental assessment of mechanical properties of joints flexion in angular plane. Furthermore work considers assessment of joint firmness and comparison between various joint types. Paper encloses the review of various joint manufacturing designs (tenon and mortise, which were proposed for its suitable mechanical properties and simplicity of manufacturing. Designated joint type is easiest form of joint construction and technologically feasible for chair manufacturing. The joints were constructed from fir wood. Further the work introduces design of simple seat construction made from massive wood material manufactured by low-end technology with regards to achieving the due specifications. The task of this work is to design the viable manufacturing process of seats and chairs from raw wood and scrap material. Essential part of work is also manufacturing of seat prototype and simplified model of proposed mortise and tenon drill.

  7. Characteristics of highly successful orthopedic surgeons: a survey of orthopedic chairs and editors

    Science.gov (United States)

    Klein, Guy; Hussain, Nasir; Sprague, Sheila; Mehlman, Charles T.; Dogbey, Godwin; Bhandari, Mohit

    2013-01-01

    Background Highly successful orthopedic surgeons are a small group of individuals who exert a large influence on the orthopedic field. However, the characteristics of these leaders have not been well-described or studied. Methods Orthopedic surgeons who are departmental chairs, journal editors, editorial board members of the Journal of Bone and Joint Surgery (British edition), or current or past presidents of major orthopedic associations were invited to complete a survey designed to provide insight into their motivations, academic backgrounds and accomplishments, emotional and physical health, and job satisfaction. Results In all, 152 surgeons completed the questionnaire. We identified several characteristics of highly successful surgeons. Many have contributed prolific numbers of publications and book chapters and obtained considerable funding for research. They were often motivated by a “desire for personal development (interesting challenge, new opportunities),” whereas “relocating to a new institution, financial gain, or lack of alternative candidates” played little to no role in their decisions to take positions of leadership. Most respondents were happy with their specialty choice despite long hours and high levels of stress. Despite challenges to their time, successful orthopedic surgeons made a strong effort to maintain their health; compared with other physicians, they exercise more, are more likely to have a primary care physician and feel better physically. Conclusion Departmental chairs, journal editors and presidents of orthopedic associations cope with considerable demands of clinical, administrative, educational and research duties while maintaining a high level of health, happiness and job satisfaction. PMID:23706848

  8. Stability Ball Sitting versus Chair Sitting During Sub-maximal Arm Ergometry.

    Science.gov (United States)

    Marks, Charles R C; Hylland, Kristina E; Terrell, Jacob

    It was predicted that sitting on a stability ball during arm ergometry would elevate cardiovascular parameters when compared to sitting on a chair and that this would be associated with greater recruitment of trunk and leg skeletal muscles. Open-circuit spirometry, videotaping, blood pressure, heart rate, and EMG were conducted during rest and four minute stages of 15 W, 30 W, and 45 W using a Monark arm ergometer. Twenty-six apparently healthy adults exercised twice, once sitting on a stability ball and the other sitting on a chair (order randomized), with 45 to 60 minutes of rest between. ANOVA for repeated measures and paired-t testing were used for analysis. Oxygen consumption was significantly 10 to 16% higher during exercise while sitting on the stability ball. There were no significant differences between sitting modes for heart rate, SBP, and DBP. Also, resting and exercise rectus femoris and 45 W external oblique EMGs were significantly higher on the stability ball. Finally, the knee was significantly more extended with the feet farther apart and more forward on the stability ball. The stability ball significantly elevates oxygen consumption during sub-maximal arm cranking without significantly increasing heart rate or blood pressure and this is associated with increased thigh muscle activation and lower leg repositioning.

  9. Correlated Random Systems Five Different Methods : CIRM Jean-Morlet Chair

    CERN Document Server

    Kistler, Nicola

    2015-01-01

    This volume presents five different methods recently developed to tackle the large scale behavior of highly correlated random systems, such as spin glasses, random polymers, local times and loop soups and random matrices. These methods, presented in a series of lectures delivered within the Jean-Morlet initiative (Spring 2013), play a fundamental role in the current development of probability theory and statistical mechanics. The lectures were: Random Polymers by E. Bolthausen, Spontaneous Replica Symmetry Breaking and Interpolation Methods by F. Guerra, Derrida's Random Energy Models by N. Kistler, Isomorphism Theorems by J. Rosen and Spectral Properties of Wigner Matrices by B. Schlein. This book is the first in a co-edition between the Jean-Morlet Chair at CIRM and the Springer Lecture Notes in Mathematics which aims to collect together courses and lectures on cutting-edge subjects given during the term of the Jean-Morlet Chair, as well as new material produced in its wake. It is targeted at researchers, i...

  10. Gamming Chairs and Gimballed Beds: Seafaring Women on Board Nineteenth-Century Ships

    Science.gov (United States)

    Seaborn, Laurel

    2017-04-01

    During the nineteenth century, many captains' wives from New England took up residence on the ships their husbands commanded. This article focuses on how those women at sea attempted to use material culture to domesticate their voyaging space. While writing in their journals, they referred to not only the small personal things such as books and knitting needles that they brought in their trunks, but also large items, built for and used by women, such as gamming chairs, deckhouses, parlor organs, sewing machines, and gimballed beds. Mary Brewster attempted to retreat from the ship's officers in her small deckhouse, Annie Brassey slept in the gimballed bed, and Lucy Lord Howes disembarked in a gamming chair when captured by Confederates during the Civil War. Evidence of these artifacts found during shipwreck archaeology could be used to further what is known of the culture aboard ships on which women lived. Analysis of the material culture reveals how a captain's wife domesticated space, altered her environment, and made a home on the ship for her family.

  11. Evolved Gas Analyses of the Murray Formation in Gale Crater, Mars: Results of the Curiosity Rover's Sample Analysis at Mars (SAM) Instrument

    Science.gov (United States)

    Sutter, B.; McAdam, A. C.; Rampe, E. B.; Thompson, L. M.; Ming, D. W.; Mahaffy, P. R.; Navarro-Gonzalez, R.; Stern, J. C.; Eigenbrode, J. L.; Archer, P. D.

    2017-01-01

    The Sample Analysis at Mars (SAM) instrument aboard the Mars Science Laboratory rover has analyzed 13 samples from Gale Crater. All SAM-evolved gas analyses have yielded a multitude of volatiles (e.g., H2O, SO2, H2S, CO2, CO, NO, O2, HCl) [1- 6]. The objectives of this work are to 1) Characterize recent evolved SO2, CO2, O2, and NO gas traces of the Murray formation mudstone, 2) Constrain sediment mineralogy/composition based on SAM evolved gas analysis (SAM-EGA), and 3) Discuss the implications of these results relative to understanding the geological history of Gale Crater.

  12. A pilot study investigating the feasibility of symptom assessment manager (SAM), a Web-based real-time tool for monitoring challenging behaviors.

    Science.gov (United States)

    Loi, Samantha M; Wanasinghage, Sangeeth; Goh, Anita; Lautenschlager, Nicola T; Darby, David G; Velakoulis, Dennis

    2017-11-03

    Improving and minimizing challenging behaviors seen in psychiatric conditions, including behavioral and psychological symptoms of dementia are important in the care of people with these conditions. Yet there is a lack of systematic evaluation of these as a part of routine clinical care. The Neuropsychiatric Inventory is a validated and reliable tool for rating the severity and disruptiveness of challenging behaviors. We report on the evaluation of a Web-based symptom assessment manager (SAM), designed to address the limitation of previous tools using some of the Neuropsychiatric Inventory functions, to monitor behaviors by staff caring for people with dementia and other psychiatric conditions in inpatient and residential care settings. The SAM was piloted in an 8-bed inpatient neuropsychiatry unit over 5 months. Eleven nurses and 4 clinicians were trained in usage of SAM. Primary outcomes were usage of SAM and perceived usability, utility, and acceptance of SAM. Secondary outcomes were the frequencies of documented behavior. Usage data were analyzed using chi-square and logistic regression analyses. The SAM was used for all admitted patients regardless of diagnosis, with a usage rate of 64% for nurses regularly employed in the unit. Staff provided positive feedback regarding the utility of SAM. The SAM appeared to offer individualized behavior assessment by providing a quick, structured, and standardized platform for assessing behavior in a real-world setting. Further research would involve trialing SAM with more staff in alternative settings such as in home or residential care settings. Copyright © 2017 John Wiley & Sons, Ltd.

  13. Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.

    Science.gov (United States)

    Papakostas, George I

    2009-01-01

    Despite the increasingly large array of antidepressants available to treat major depressive disorder, patients continue to experience relatively modest response and remission rates. In addition, patients may experience adverse side effects from pharmacotherapy that not only hinder treatment compliance and adherence but, in some cases, may also contribute to increased disability, patient suffering, morbidity, and mortality. In order to enhance treatment efficacy and tolerability, patients and clinicians have become increasingly interested in nonpharmaceutical supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-L-methionine (SAM-e), a naturally occurring molecule present in all living cells and a major methyl group donor in the human body. Controlled trials have found SAM-e to be more efficacious than placebo and equal in efficacy to the tricyclic antidepressants for treating major depressive disorder (MDD) when administered parenterally (either intravenously or intramuscularly). Less evidence supports the use of oral SAM-e, although some trials have demonstrated its efficacy as well. In addition, there is a paucity of evidence examining whether oral forms of SAM-e can be safe, well tolerated, and efficacious when used as adjunctive treatment for antidepressant nonresponders with MDD. Although preliminary data suggest SAM-e may be useful as an adjunctive therapy to antidepressants, controlled studies are needed to confirm or refute these preliminary findings. (c) Copyright 2009 Physicians Postgraduate Press, Inc.

  14. Potensi Tinggalan Arkeologis di Kawasan Bandar Udara Sam Ratulangi Manado: Upaya Pelestarian, Pemanfaatan, dan Pengembangan bagi Masyarakat

    Directory of Open Access Journals (Sweden)

    Irfanuddin W. Marzuki

    2016-08-01

    Full Text Available The area of Sam Ratulangi airport’s Manado has archaeological heritage which has been know as it is closed for public. This research used descriptive method, using inductive reasoning. Meanwhile, the analysis method used morphologyl, technology, and contextual analysis. This research aimed to find out the potential of archaeological heritage in Sam Ratulangi airport area of Manado. In addition to its strategy of preservation the haritage included veilbox, bungker, and waruga. The preservation can be conducted by doing protection, development, and utilization. The preservation both physical and non physical protection. The effort for its development and utilization was conducted for the purpose of science, education, culture, and tourism. Kawasan Bandar Udara Sam Ratulangi Manado mempunyai potensi tinggalan arkeologis yang selama ini tidak diketahui masyarakat luas, dikarenakan letak tinggalan yang berada dalam kawasan tertutup untuk umum. Penelitian menggunakan metode deskriptif dengan penalaran induktif. Metode analisis menggunakan analisis morfologi, teknologi dan kontekstual. Tujuan penelitian untuk mengetahui potensi tinggalan arkeologis yang terdapat di kawasan Bandar Udara Sam Ratulangi dan strategi pelestariannya. Tinggalan arkeologis yang terdapat di kawasan Bandar Udara Sam Ratulangi meliputi veilbox, bungker, dan waruga. Upaya pelestarian dapat dilakukan dengan cara perlindungan, pengembangan dan pemanfaatan. Upaya perlindungan meliputi perlindungan secara fisik dan non fisik. Upaya pengembangan dan pemanfaatan dilakukan untuk kepentingan ilmu pengetahuan, pendidikan, kebudayaan dan pariwisata.

  15. The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.

    Science.gov (United States)

    Pendleton, Kathryn E; Chen, Beibei; Liu, Kuanqing; Hunter, Olga V; Xie, Yang; Tu, Benjamin P; Conrad, Nicholas K

    2017-05-18

    Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N6-adenosine methyltransferase METTL16 regulates expression of human MAT2A, which encodes the SAM synthetase expressed in most cells. Upon SAM depletion by methionine starvation, cells induce MAT2A expression by enhanced splicing of a retained intron. Induction requires METTL16 and its methylation substrate, a vertebrate conserved hairpin (hp1) in the MAT2A 3' UTR. Increasing METTL16 occupancy on the MAT2A 3' UTR is sufficient to induce efficient splicing. We propose that, under SAM-limiting conditions, METTL16 occupancy on hp1 increases due to inefficient enzymatic turnover, which promotes MAT2A splicing. We further show that METTL16 is the long-unknown methyltransferase for the U6 spliceosomal small nuclear RNA (snRNA). These observations suggest that the conserved U6 snRNA methyltransferase evolved an additional function in vertebrates to regulate SAM homeostasis. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Kinematic analysis of posterior-stabilized total knee arthroplasty during standing up from and sitting down on a chair.

    Science.gov (United States)

    Mine, Takatomo; Hoshi, Kenji; Gamada, Kazuyoshi; Ihara, Koichiro; Kawamura, Hiroyuki; Kuriyama, Ryutaro; Date, Ryo

    2016-11-17

    Total knee arthroplasty is effective to regain quality of life. Standing up from and sitting down on a chair and stair stepping motion are important in daily living. We previously reported in vivo kinematics of this implant during a stepping exercise. The purpose of this analysis was to assess in vivo knee motion during standing up from and sitting down on a chair and determine the motion pattern in patients with the unique knee prosthesis. A total of 15 patients implanted with Bi-Surface PS were assessed during standing up from and sitting down on a chair. The Bi-Surface PS knee is a posterior-cruciate substitute prosthesis with a unique ball-and-socket joint in the mid-posterior portion of the femoral and tibial components. Patients were examined during standing up from and sitting down on a chair using a two-dimensional to three-dimensional registration technique. During standing up from and sitting down on a chair from minimum to 30° knee flexion, anterior femoral translation was slight. From 30° knee flexion to maximum flexion, the kinematic pattern was a medial pivot and rollback. This study demonstrated that the knee motion kinematic patterns observed in this study were not similar to normal knee kinematics and derived from the unique design of the Bi-Surface PS.

  17. School Desk and Chair Design Based on High School Female Students Anthropometry Qazvin, Iran 2007 to 2008

    Directory of Open Access Journals (Sweden)

    T. Aivazloo

    2008-10-01

    Full Text Available Background and ObjectivesAnthropometry data compiled from body dimensions of female high school students are used to optimize the design of desks and chairs for the classrooms of these students. It is necessary to design suitable desk/chair based on anthropometry data in order to reduce musculoskeletal, visual, circulatory problems, and bad posture during long hours of studying.The goal of this study is to design desks/chairs based on the standard BS 5873 using the body dimensions of 240 female high school students.Methods240 female students, between the ages of 15 to 17 years old were selected from six different high schools in district 2 of city of Qazvin in Iran. Data for this study were gathered using an interview method and anthropometry measurement devices. Results Eighteen body dimension parameters of 240 female high school students were obtained. The collected data were analyzed and compared to the standard using SPSS methods. The participant students were divided into 2 groups and customized desk/chair designs were built to fit their body dimensions. ConclusionThere is a significant difference between each customized desk and chair dimension, and standard dimensions used in the industry with an exception of the heights of these designs. We suggest that customized designs based on body dimensions promote correct posture, comfort and health.Keywords: Human Ergonomics; Anthropometry; Equipment Design.

  18. A Study on the Optimization of Surfactants in the Main and Vice Slug in Weak Base ASP Flooding

    Directory of Open Access Journals (Sweden)

    Bin Huang

    2017-03-01

    Full Text Available In ASP (Alkali-Surfactant-Polymer flooding processes, surfactants help to enhance oil recovery by lowering the interfacial tension between the oil and water. However, due to the high cost of surfactants and the stability of the emulsion that varies with surfactant concentration, it is necessary to optimize the surfactant concentration in ASP flooding. In this study, we combined numerical simulation and physical experimental research to solve this problem. In order to screen for the optimal surfactant concentration in the main and vice slugs, CMG (Computer Measurement Group numerical simulation software was used to change the surfactant concentration in the injected compound system and the oil recovery factor and the recovery percent of reserves were compared. The physical experiments were also carried out with different surfactant concentrations and the results verified the simulation results. It shows that the recovery factor increases with the surfactant concentration. The optimal surfactant concentration in the main and vice slug are 0.3% and 0.15%, respectively. As for improving the recovery factor, it is more efficient to increase the mass fraction of the surfactant in the vice slug than in the main slug. It demonstrates that the amount of surfactant in the main slug plays a more important role in displacing oil from the formation.

  19. Lunch hosted by Professor Sissakian, vice-director of the Joint Institute for Nuclear Research, Dubna to Gordon Fraser and Jim Allaby.

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    who are retiring from CERN, were presented with diplomas of honour. Allaby co-chaired the CERN-JINR joint scientific committee for many years and Fraser is editor of the CERN Courier until January 2002.

  20. Resilience as positive coping appraisals: Testing the schematic appraisals model of suicide (SAMS).

    Science.gov (United States)

    Johnson, J; Gooding, P A; Wood, A M; Tarrier, N

    2010-03-01

    The Schematic Appraisals Model of Suicide (SAMS) suggests that positive self-appraisals may be important for buffering suicidal thoughts and behaviours, potentially providing a key source of resilience. The current study aimed to explore whether positive self-appraisals buffered individuals from suicidality in the face of stressful life events. 78 participants who reported experiencing some degree of suicidality were recruited from a student population. They completed a battery of questionnaires including measures of suicidality, stressful life events and positive self-appraisals. Positive self-appraisals moderated the association between stressful life events and suicidality. For those reporting moderate or high levels of positive self-appraisals, raised incidence of stressful life events did not lead to increases in suicidality. These results support the SAMS framework, and suggest that positive self-appraisals may confer resilience to suicide. Positive self-appraisals may be a promising avenue for further resilience research, and an important area to target for suicide interventions. 2009 Elsevier Ltd. All rights reserved.

  1. SAM - Sistema Automatizado del Método MECAP para Especificar Casos de Prueba

    Directory of Open Access Journals (Sweden)

    Kenyer Domínguez

    2010-12-01

    Full Text Available Existen cuatro elementos que son relevantes al momento de definir las pruebas: Confiabilidad, Costo, Tiempo y Calidad. El tiempo de desarrollo y el costo del producto se incrementan cuando se desean pruebas confiables y un software de calidad. Pero ¿qué se puede hacer para que los involucrados comprendan que las pruebas deben ser vistas como una red de seguridad? Si la calidad no se contempla antes de comenzar las pruebas, entonces ella no estará cuando se éstas terminen. El objetivo de este artículo es presentar la herramienta, SAM – Sistema Automatizado del Método MECAP que permite especificar Casos de Prueba a partir de Casos de Uso incorporando elementos que promueven la verificación y validación de la trazabilidad entre la Gestión de Requerimientos, el Análisis y Diseño y las Pruebas. SAM soporta el proceso de pruebas de forma automatizada, mejorando la confiabilidad de las mismas

  2. Absence of molecular slip on ultraclean and SAM-coated surfaces

    Science.gov (United States)

    Pye, Justin; Wood, Clay; Burton, Justin

    2016-11-01

    The liquid/solid boundary condition is a complex problem that is becoming increasingly important for the development of nanoscale fluidic devices. Many groups have now measured slip near an interface at nanoscale dimensions using a variety of experimental techniques. In simple systems, large slip lengths are generally measured for non-wetting liquid/solid combinations, but many conflicting measurements and interpretations remain. We have developed a novel pseudo-differential technique using a quartz crystal microbalance (QCM) to measure slip lengths on various surfaces. A drop of one liquid is grown on the QCM in the presence of a second, ambient liquid. We have isolated any anomalous boundary effects such as interfacial slip by choosing two liquids which have identical bulk effects on the QCM frequency and dissipation in the presence of no-slip. Slip lengths are -less than 2 nm- for water (relative to undecane) on all surfaces measured, including plasma cleaned gold, SiO2, and two different self assembled monolayers (SAMs), regardless of contact angle. We also find that surface cleanliness is crucial to accurately measure slip lengths. Additionally, clean glass substrates appear to have a significant adsorbed water layer and SAM surfaces show excess dissipation, possibly associated with contact line motion. In addition to investigating other liquid pairs, future work will include extending this technique to surfaces with independently controllable chemistry and roughness, both of which are known to strongly affect interfacial hydrodynamics.

  3. Constraining the MSL-SAM methane detection source location Through Mars Regional Atmospheric Modeling System (MRAMS)

    Science.gov (United States)

    Pla Garcia, J.; Rafkin, S. C. R.

    2017-09-01

    The detection of methane by SAM instrument has garnered significant attention. There are many major unresolved questions regarding this detection: 1) Where is the release location? 2) How spatially extensive is the release? 3) For how long is CH4 released? In an effort to better address the potential mixing and remaining questions, atmospheric circulation studies of Gale Crater were performed with MRAMS mesoscale model, ideally suited for this investigation. The model was focused on rover locations using nested grids with a spacing of 330 meters on the innermost grid that is centered over the detection site. In order to characterize seasonal mixing changes throughout the Martian year, simulations were conducted at Ls0, 90, 180 and 270. The rise in CH4 concentration was reported to start around Ls336, peaked shortly after Ls82, and then dropped to background prior to Ls103. The aim of this work is to establish the amount of mixing during all seasons and to test whether CH4 releases inside or outside of Gale crater are consistent with SAM observations.

  4. Human and management factors in probabilistic risk analysis: the SAM approach and observations from recent applications

    Energy Technology Data Exchange (ETDEWEB)

    Elisabeth Pate-Cornell, M.; Murphy, Dean M

    1996-08-01

    Most severe industrial accidents have been shown to involve one or more human errors and these are generally rooted in management problems. The objective of this paper is to draw some conclusions from the experience that we have acquired from three different studies of this phenomenon: (1) the Piper Alpha accident including problems of operations management and fire risks on-board offshore platforms, (2) the management of the heat shield of the NASA space shuttle orbiter, and (3) the roots of patient risks in anaesthesia. This paper describes and illustrates the SAM approach (System-Action-Management) that was developed and used in these studies to link the probabilities of system failures to human and management factors. This SAM model includes: first, a probabilistic risk analysis of the physical system, second, an analysis of the decisions and actions that affect the probabilities of its basic events, and third, a study of the management factors that influence those decisions and actions. In the three initial studies, the analytical links (conditional probabilities) among these three submodels were coarsely quantified based on statistical data whenever available, or most often, on expert opinions. This paper describes some observations that were made across these three studies, for example, the importance of the informal reward system, the difficulties in the communication of uncertainties, the problems of managing resource constraints, and the safety implications of the short cuts that they often imply.

  5. Post-translational modification of ribosomally synthesized peptides by a radical SAM epimerase in Bacillus subtilis

    Science.gov (United States)

    Benjdia, Alhosna; Guillot, Alain; Ruffié, Pauline; Leprince, Jérôme; Berteau, Olivier

    2017-07-01

    Ribosomally synthesized peptides are built out of L-amino acids, whereas D-amino acids are generally the hallmark of non-ribosomal synthetic processes. Here we show that the model bacterium Bacillus subtilis is able to produce a novel type of ribosomally synthesized and post-translationally modified peptide that contains D-amino acids, and which we propose to call epipeptides. We demonstrate that a two [4Fe-4S]-cluster radical S-adenosyl-L-methionine (SAM) enzyme converts L-amino acids into their D-counterparts by catalysing Cα-hydrogen-atom abstraction and using a critical cysteine residue as the hydrogen-atom donor. Unexpectedly, these D-amino acid residues proved to be essential for the activity of a peptide that induces the expression of LiaRS, a major component of the bacterial cell envelope stress-response system. Present in B. subtilis and in several members of the human microbiome, these epipeptides and radical SAM epimerases broaden the landscape of peptidyl structures accessible to living organisms.

  6. Estimation of Comfortable/Uncomfortable Feeling Based on EEG by Using NN and k-means Algorithm for Massage Chair

    Science.gov (United States)

    Teramae, Tatsuya; Kushida, Daisuke; Takemori, Fumiaki; Kitamura, Akira

    A present massage chair realizes the massage motion and force designed by a professional masseur. However, appropriate massage force to the user can not be provided by the massage chair in such a method. On the other hand, the professional masseur can realize an appropriate massage force to more than one patient, because, the masseur considers the physical condition of the patient. Our research proposed the intelligent massage system of applying masseur's procedure for the massage chair using estimated skin elasticity and DB to relate skin elasticity and massage force. However, proposed system has a problem that DB does not adjust to unknown user, because user's feeling by massage can not be estimated. Then, this paper proposed the estimation method of comfortable/uncomfortable feeling based on EEG using the neural network and k-means algorithm. The realizability of the proposed method is verified by the experimental works.

  7. A Globally Distributed Grid Monitoring System to Facilitate High-Performance Computing at D0/SAM-Grid

    Energy Technology Data Exchange (ETDEWEB)

    Rana, Abhishek S. [Texas U., Arlington

    2002-01-01

    A grid environment involves large scale sharing of resources that are distributed from a geographical or an administrative perspective. There is a need for systems that enable continuous discovery and monitoring of the components of a grid. In this work, we discuss the development and deployment of a monitoring system that has been designed as a prototype for the D0/SAM-Grid. We have developed a system that uses a layered architecture for information generation and processing, utilizes the various grid middleware tools, and implements Integration and Enquiry Protocols using existing Discovery Protocols to provide a user with a coherent view of all current activity in this grid - in the form of a web portal interface. The prototype system has been deployed for monitoring of 11 sites geographically distributed in 5 countries across 3 continents. This work focuses on the D0/SAM-Grid, and is based on the SAM system developed at Fermilab.

  8. Relationship between Features of Desks and Chairs and Prevalence of Skeletal Disorders in Primary School Students in Abadan

    Directory of Open Access Journals (Sweden)

    Yadollah Zakeri

    2016-11-01

    Full Text Available BackgroundSitting on inappropriate benches, as well as the poor posture (body position during the years of growth, can lead to spinal disorders, fatigue and discomfort in students. This study aimed to investigate the relationship between features of desks and chairs and prevalence of some musculoskeletal disorders in primary school students in Abadan.Materials and MethodsThis cross-sectional study was conducted in 2015 in the city of Abadan- South West of Iran; for which, 383 primary school students were selected and studied through cluster sampling method. Data were collected by the checkered board and researcher-made questionnaire. Features and dimensions of desks and chairs of students were recorded and evaluated based on their condition (being standard or not. Statistical analysis was conducted using SPSS, version 22; and then, descriptive statistics and Chi-square test were conducted.ResultsStudy results showed that about 56.1% of the desks and chairs in under study schools were non-standard. It found that drooping shoulder (85.4% and scoliosis (81.7% were the more prevalent disorders and back straight (1.6% was the least frequent disorder. There was a significant relationship between the variable of non-standard desks and chairs and prevalence of drooping shoulders (P=0.001, scoliosis (P= 0.04, kyphosis (P=0.007 and lordosis (P=0.002 disorders in students.ConclusionThe non-standard-sized desks and chairs increase the prevalence of skeletal disorders in schoolchildren. Therefore, it is essential to pay attention to design and build standard classroom desks and chairs, which are best, adjust to students’ physics.

  9. Fabrication and tribological properties of self-assembled monolayer of n-alkyltrimethoxysilane on silicon: Effect of SAM alkyl chain length

    Energy Technology Data Exchange (ETDEWEB)

    Huo, Lixia [National Key Laboratory of Science and Technology on Vacuum Technology and Physics, Lanzhou Institute of Physics, Lanzhou, Gansu 730010 (China); Institute of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Lanzhou University, Gansu 730000 (China); Du, Pengcheng [Institute of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Lanzhou University, Gansu 730000 (China); Zhou, Hui; Zhang, Kaifeng [National Key Laboratory of Science and Technology on Vacuum Technology and Physics, Lanzhou Institute of Physics, Lanzhou, Gansu 730010 (China); Liu, Peng, E-mail: pliu@lzu.edu.cn [Institute of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Lanzhou University, Gansu 730000 (China)

    2017-02-28

    Highlights: • n-Alkyltrimethoxysilanes with various chain lengths were self-assembled on silicon. • Effect of alkyl chain lengths (C6, C12, or C18) on the SAMs was investigated. • Surface roughness of the SAMs decreased with increasing the alkyl chain lengths. • The C{sub 12}-SAM possessed superior friction reduction and wear resistance. - Abstract: It is well known that the self-assembled organic molecules on a solid surface exhibit the friction-reducing performance. However, the effect of the molecular size of the self-assembled organic molecules has not been established. In the present work, self-assembled monolayers (SAMs) of n-alkyltrimethoxysilanes with different alkyl chain lengths (C{sub 6}, C{sub 12}, or C{sub 18}) were fabricated on silicon substrate. The water contact angles of the SAMs increased from 26.8° of the hydroxylated silicon substrate to near 60° after self-assembly. The atomic force microscopy (AFM) analysis results showed that the mean roughness (R{sub a}) of the SAMs decreased with increasing the alkyl chain length. The tribological properties of the SAMs sliding against Al{sub 2}O{sub 3} ball were evaluated on an UMT-2 tribometer, and the worn surfaces of the samples were analyzed by means of Nano Scratch Tester and surface profilometry. It was found that lowest friction coefficient and smallest width of wear were achieved with the SAMs of C{sub 12} alkyl chain (C{sub 12}-SAM). The superior friction reduction and wear resistance of the SAMs in comparison with the bare silicon substrate are attributed to good adhesion of the self-assembled films to the substrate, especially the C{sub 12}-SAM with desirable alkyl chain length.

  10. Franchising as a Potential Growth Strategy for a Small Business : A Case of Sam-Chi Fast Food Restaurant

    OpenAIRE

    Odunsi, Sadiq

    2015-01-01

    The purpose of this study was to find out whether Sam-Chi fast food restaurant can grow through franchising as well as to give the owners recommendations on how to effectively adopt the franchising business model as a means to grow their business. Sam-Chi restaurant is situated in Lagos, Nigeria and the restaurant is owned and operated by Samuel Okore and his wife Chichi Okore. The theoretical framework of this research is separated into two sections. The first section covers the growth of a ...

  11. Hierarchical Storage Management at the NASA Center for Computational Sciences: From UniTree to SAM-QFS

    Science.gov (United States)

    Salmon, Ellen; Tarshish, Adina; Palm, Nancy; Patel, Sanjay; Saletta, Marty; Vanderlan, Ed; Rouch, Mike; Burns, Lisa; Duffy, Daniel; Caine, Robert

    2004-01-01

    This paper presents the data management issues associated with a large center like the NCCS and how these issues are addressed. More specifically, the focus of this paper is on the recent transition from a legacy UniTree (Legato) system to a SAM-QFS (Sun) system. Therefore, this paper will describe the motivations, from both a hardware and software perspective, for migrating from one system to another. Coupled with the migration from UniTree into SAM-QFS, the complete mass storage environment was upgraded to provide high availability, redundancy, and enhanced performance. This paper will describe the resulting solution and lessons learned throughout the migration process.

  12. New Congressional science chair to focus on education, energy policy, and environment

    Science.gov (United States)

    Showstack, Randy

    2001-02-01

    With the re-shuffling of the leadership of Congressional committees following the recent U.S. general elections, Sherwood L. Boehlert, a 10-term congressman from upstate New York, has been selected by the Republican leadership to be the chair of the Science Committee in the House of Representatives. During his January 31 "maiden" speech as the new committee leader, Boehlert told members of the Universities Research Group, "I want to build the Science Committee into a significant force within the Congress. With that momentum, I want to ensure that we have a healthy, sustainable, and productive [research and development] establishment; one that educates students, increases human knowledge, strengthens U.S. competitiveness, and contributes to the well-being of the nation and the world."

  13. Biomechanics of rising from a chair and walking in pregnant women.

    Science.gov (United States)

    Sunaga, Yasuyo; Anan, Masaya; Shinkoda, Koichi

    2013-09-01

    The present study aimed to assess the changes in the pattern of rising from a chair and walking forward as pregnancy progressed. Twelve pregnant women and 10 nulliparous women were included in this study. Participants were videotaped with a digital video camera in the sagittal plane, and the coordinates of the markers attached to the subjects were identified using image analysis software. The peak trunk-flexion angle in pregnant women during rising was smaller, but the hip-extension angle during the stance phase was larger than in controls. Also, the peak horizontal and vertical velocities of the center of mass were lower, and appeared earlier, in pregnant women than in controls. During rising, pregnant women dampened the propulsion attributable to increased uterus volume, and they enhanced the forward propulsion at gait initiation. To ensure safe motion, pregnant women should not initiate gait until reaching a stable standing position after rising. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  14. 31 March 2016 - Qatar Foundation Research and Development Executive Vice President H. Al-Ibrahim signing a Cooperation Agreement with CERN Director-General F. Gianotti.

    CERN Multimedia

    Brice, Maximilien

    2016-01-01

    Dr Hamad Al-Ibrahim Executive Vice President, Qatar Foundation Research and Development. Were present: CERN International Relations Unit, Adviser for Qatar P. Fassnacht; CERN Director for Research and Computing E. Elsen; Texas A&M Professor of Physics A. Safonov ; CERN Director for International Relations C. Warakaulle; Professor of Physics, Qatar University I.Al-Qaradawi; Executive Vice President H. Al-Ibrahim; CERN Director-General F. Gianotti; Ambassador Faisal Bin Abdulla Al-Henzab to the UNOG; Director of Research Computing, Texas A&M, Qatar O. Bouhali; Vice Dean, Texas A&M, Qatar E. Massad; Executive Director, Research Coordination & Special Initiatives, Qatar Foundation R&D D. Khoury.

  15. Discrimination against female surgeons is still alive: Where are the full professorships and chairs of departments?

    Science.gov (United States)

    Epstein, Nancy E

    2017-01-01

    Although half of all medical students are now and women are increasingly filling surgical residency positions, few ascend the academic ladder to become chairman of their departments, much less full academic professors. We queried PubMed to search for the number of women surgeons in different subspecialties, and asked how many were chairman or full academic professors? Data coming out of largely general or cardiothoracic surgery departments cited no substantial gains for women surgeons over the years; there were few chairmanships or full professorships. In one study of 54 female cardiothoracic surgeons, 60% of academic appointments were at the instructor or assistant professor level; only 18% were full professors. In another study looking at 12-year data from major academic medical institutions in the US, women constituted only 9.2% of chairs, only 14.7% of full professors, and just 9.3% of deans. In a third study, out of 270 female general surgeons, there were only three who were chairman, and just 12.4% were tenured professors. In Great Britain/Ireland, of 315 neurosurgeons (25 females), all 16 full professors were males. Two medical/surgical series speculated it would take until 2096 or 2136 for females to attain 50% of full professorships. The American Association of Neurological Surgery (U.S. 2017; personal communication) showed that of 287 Board-certified female neurosurgeons, there is just one female surgeons chairman. Few female physicians/surgeons were chairs of departments or full professors at their academic institutions. Do women in medicine/surgery really need to wait until 2136 to achieve equality?

  16. Comparison of Resistance and Chair Yoga Training on Subjective Sleep Quality in MCI Women

    Directory of Open Access Journals (Sweden)

    Maria Karydaki

    2017-01-01

    Full Text Available Background: Self-rated sleep disorders are common in older adults, resulting in various health problems. Two types of exercise are suggested as an affordable and accessible non-pharmacological treatment and are being compared and discussed. Objectives: This randomized, controlled, 12-week trial investigates the effects of different types of exercise (resistance vs chair yoga training on subjective sleep quality, in women with Mild Cognitive Impairment (MCI. Methods: In order to measure cognitive function, the Mini-Mental State Examination (MMSE was used. Forty nine participants enrolled in the study were randomized to a resistance training program (n=16, or a chair yoga program (n=15, or a control group (n=18. All participants engaged in cognitive activities. Results: At baseline, PSQI scores for CYG, RTG and CG (8.2±5.1, 6.1±4.3, 7.4±4.1, respectively and MMSE (28.3±1.4, 27.8±1.2, 28.0±2.3, respectively did not differ statistically between the three groups (F2,46= 1.993, p= 0.143. After the intervention, a significant improvement in PSQI total score was noted in resistance training group (t=2.335, df15, p=0.03. Conclusions: There were no significant differences between groups before and after test for the PSQI subscale scores (sleep onset latency (h, time spent in bed before sleep (min, morning waking up (h and sleep duration (h. No significant difference was found in PSQI subscales scores within each group. This study proposes that resistance training is an effective treatment approach to improve sleep quality in women with mild cognitive impairment.

  17. DOE Chair of Excellence in Environmental Disciplines-Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Kurunganty, Sastry; Loran, Roberto; Roque-Malherbe, Rolando; Hijazi, Yazan; Nieto, Santander; Gomez, Will A.; Duconge, Jose; Cotto, María del C.; Muniz, Carlos; Diaz, Francisco J.; Neira, Carlos F.; Marquez, Francisco; Del Valle, W.; Thommes, M.

    2014-02-19

    The report Massie Chair of Excellence Program at Universidad del Turabo, contract DE-FG02-95EW12610, during the period of 9/29/1995 to 9/29/2011. The initial program aims included development of academic programs in the Environmental Sciences and Engineering, and Research and Development focused initially on environmentally friendly processes and later revised also include: renewable energy and international cooperation. From 1995 -2005, the Program at UT lead the establishment of the new undergraduate program in electrical engineering at the School of Engineering (SoE), worked on requirements to achieve ABET accreditation of the SoE B.S. Mechanical Engineering and B.S. Electrical Engineering programs, mentored junior faculty, taught undergraduate courses in electrical engineering, and revised the electrical engineering curriculum. Engineering undergraduate laboratories were designed and developed. The following research sub-project was developed: Research and development of new perovskite-alumina hydrogen permeable asymmetrical nanostructured membranes for hydrogen purification, and extremely high specific surface area silica materials for hydrogen storage in the form of ammonia, Dr. Rolando Roque-Malherbe Subproject PI, Dr. Santander Nieto and Mr. Will Gómez Research Assistants. In 2006, the Massie Chair of Excellence Program was transferred to the National Nuclear Security Agency, NNSA and DNN. DoE required a revised proposal aligned with the priorities of the Administration. The revised approved program aims included: (1) Research (2) Student Development: promote the development of minority undergraduate and graduate students through research teams, internships, conferences, new courses; and, (3) Support: (a) Research administration and (b) Dissemination through international conferences, the UT Distinguished Lecturer Series in STEM fields and at the annual Universidad del Turabo (UT) Researchers Conference. Research included: Sub-Project 1: Synthesis and

  18. NaCl stress induces CsSAMs gene expression in Cucumis sativus by mediating the binding of CsGT-3b to the GT-1 element within the CsSAMs promoter.

    Science.gov (United States)

    Wang, Li-Wei; He, Mei-Wen; Guo, Shi-Rong; Zhong, Min; Shu, Sheng; Sun, Jin

    2017-05-01

    The CsSAMs promoter is a salt-stress-inducible promoter containing three GT-1 elements that are sufficient for the salt-stress response. The transcription factor CsGT-3b was found to bind to the GT-1 element. The S-adenosyl-L-methionine synthase (SAMs) gene is among the functional genes induced during environmental stress. However, little is known about the regulatory mechanism and upstream regulators of this salt-inducible gene in cucumber plants. Thus, it is necessary to understand the characteristics of the SAMs gene by analyzing its promoter and transcription factors. In this study, we isolated and functionally analyzed a 1743-bp flanking fragment of the CsSAMs gene from Cucumis sativus. To examine promoter activity, the full-length promoter, as well as different promoter fragments, were fused to the β-glucuronidase (GUS) reporter gene and introduced into the tobacco genome. The full-length promoter displayed maximal promoter activity, whereas the P4 promoter, containing 321 bp of upstream sequence, showed no basal promoter activity. In addition, the CsSAMs promoter exhibited stress-inducible regulation rather than tissue-specific activity in transgenic tobacco. Histochemical analysis revealed strong GUS staining in leaves, stems, and roots, especially in the veins of leaves, the vascular bundle of stems, and root tip zones following NaCl stress. A transient expression assay confirmed that the 242-bp region (-1743 to -1500) was sufficient for the NaCl-stress response. Yeast one-hybrid assays further revealed interaction between the NaCl-response protein CsGT-3b and the GT-1 (GAAAAA) element within the 242-bp region. Taken together, we revealed the presence of four salt-stress-responsive elements (GT-1 cis-elements) in the CsSAMs promoter and identified a transcription factor, CsGT-3b, that specifically binds to this sequence. These results might help us better understand the intricate regulatory network of the cucumber SAMs gene.

  19. The vices of emperor Constans I in the fourth century histories

    Directory of Open Access Journals (Sweden)

    Milivojević Uroš

    2008-01-01

    Full Text Available The aim of this paper is to analyze the negative characteristics of the Roman emperor Constans I (337-350, according to the earliest preserved information from the late 4th century histories of Aurelius Victor, Eutropius Pseudo-Victor and Eunapius of Sardis. The earliest account of Constans' downfall is around 361 recorded by Aurelius Victor in his short history De Caesaribus. Victor wrote that Constans became more arrogant and aggressive after he defeated his elder brother Constantine II in 340. Also, he was not cautious enough for his young age, was hated due to his bad subordinates and did not respect his soldiers properly. But, the most outrageous fact was according to Victor, that the emperor had homosexual affinity towards his young and attractive barbarian hostages. The record of less moralistic Eutropius in his Breviarium ab Urbe condita, written in 369, is shorter but sharper. In the beginning the reign of Constans was vigorous and righteous but his character deteriorated after his illness. Following that, the young Augustus befriended himself with corrupted companions and turned to severe vices. His reign grew unbearable to his subjects and unpopular among the army ranks. Briefer then Eutropis is the testimony of an anonymous Latin author of Epitome de caesaribus who was contemporary to the Eastern Roman emperor Arcadius (395-408. This Pseudo-Victor wrote down that Constans devoted himself to hunting session, thus allowing plotters to dethrone him. Finally the single Greek author in this series, Eunapius (died after 404, whose istoria h meta Dexippon survived in fragments and Zosimus' late fifth century abridgment, called Constans the worst among the most intolerable tyrants. The Lydian sophist, as far as we could conclude from Zosimus', also recorded Constans' inclination towards young barbarians whom he allowed to mistreat his subjects. Because of wretchedness in the provinces of his realm, the courtiers led coup d'etat through

  20. Bright lights: disclosures from the optical, spectroscopic and chromatographic characterization of a 19th century Portuguese sedan chair

    Directory of Open Access Journals (Sweden)

    Catarina Miguel

    2016-01-01

    Full Text Available The Fundação Ricardo Espírito Santo Silva (FRESS as the mission of defend, train, study, develop and implement Portuguese Fine Arts in Portugal. This paper reflects the process of Conservation-Restoration training, where students apply the most recent analytical techniques to the characterization of artwork towards enabling and supporting conservation intervention. In this study, the materials used to produce a 19th century sedan chair were characterised by optical microscopy, spectroscopic (SEM-EDS, -Raman and FTIR-imaging and chromatographic (HPLC-DAD/MS techniques. The use of natural and synthetic dyes was identified in textiles found inside the chair, including cochineal, brazilwood and fuchsine. Several paint layers with different colours and compounds, such as barite, calcium carbonate, lead white, hematite and Prussian blue, were identified in the external painted wood surface of the chair. The variety of identified materials, interspersed between layers of animal glue, reflects the different interventions that took place on the chair over time, supporting the intervention strategies reported/prescribed for the conservation-restoration procedure.

  1. Is the Process the Problem? Impact of Selection Methods on Reported Job Satisfaction among Academic Department Chairs

    Science.gov (United States)

    Fairchild, Julie E.

    2013-01-01

    The problem of low job satisfaction (JS) among academic department chairs (ADC) may result from the selection process. ADC searches seldom comply with best practices for hiring or are predictive of a good fit. Formal searches are seldom used. Some incumbents did not want the job. Research into the history, nature, and problems of the position…

  2. Hitchcock versus Shaker Chairs: Artifacts to Teach about the Rise and Rejection of Industrialism in the Young Republic

    Science.gov (United States)

    Morris, Ronald V.

    2006-01-01

    This article describes a group students in an elementary gifted class used discovery to learn about life in industrial New England. Taking multiple days to analyze this topic, students used artifacts (chairs), discussion, and primary sources to explore the politics of the 1830s. They examined the workings of Hitchcockville, CT, and a Massachusetts…

  3. 77 FR 59975 - Certain Folding Metal Tables and Chairs From China; Institution of a Five-Year Review Concerning...

    Science.gov (United States)

    2012-10-01

    ... existence and availability of substitute products; and the level of competition among the Domestic Like... is China. (3) The Domestic Like Product is the domestically produced product or products which are... Domestic Like Products consisting of certain folding metal chairs and certain folding metal tables, which...

  4. The perception of science department chairs regarding the performance of community college science majors transferring to 4-year institutions

    Science.gov (United States)

    Ford, Brenda Jordan

    The purpose for conducting the study was to determine the perceptions held by science department chairs toward 2-year college transfer students regarding their ability to succeed in upper level science courses as compared to that of native students. A two-section, researcher-developed questionnaire was utilized to collect data. The first section was related to demographic information about the department chair's institution, such as institution size, number of transfer students at the institution, and the post-graduate plans of students. The second section presented 15 skills that if found in students should lead to academic success. A total of 61 (N = 61) surveys were returned, representing an overall return rate of 54.4%. The mean, the standard deviation, and paired t-tests were used to analyze the data. Results showed that science department chairs perceived significant differences in native and transfer students. The significant differences found between native and transfer students became greater as the size of the institution increased. The significant differences found between native and transfer students became less the greater the number of transfer students attending an institution. Significant differences were found between students planning to attend professional school and students going to jobs after graduation. No significant differences were found between students going to graduate school and those who were undecided about post-graduation plans. Two-year college transfer students were perceived by department chairs as having the ability to be academically successful at 4-year institutions.

  5. 76 FR 2883 - Folding Metal Tables and Chairs From the People's Republic of China: Final Results of 2007-2008...

    Science.gov (United States)

    2011-01-18

    ... Staples' ``Complete Office-To-Go,'' a folding chair with a tubular steel frame and a seat and back of... foam and covered with fabric or polyvinyl chloride, attached to the tubular steel seat frame with... exclusively from steel or other metal, as described below: (1) Assembled and unassembled folding tables made...

  6. Graduate Medical Education Funding and Curriculum in Physical Medicine and Rehabilitation: A Survey of Physical Medicine and Rehabilitation Department Chairs.

    Science.gov (United States)

    Perret, Danielle; Knowlton, Tiffany; Worsowicz, Gregory

    2018-03-01

    This national survey highlights graduate medical education funding sources for physical medicine and rehabilitation (PM&R) residency programs as well as perceived funding stability, alignment of the current funding and educational model, the need of further education in postacute care settings, and the practice of contemporary PM&R graduates as perceived by PM&R department/division chairs. Approximately half of the reported PM&R residency positions seem to be funded by Centers of Medicare and Medicaid Services; more than 40% of PM&R chairs believe that their residency program is undersized and nearly a quarter feel at risk for losing positions. A total of 30% of respondents report PM&R resident experiences in home health, 15% in long-term acute care, and 52.5% in a skilled nursing facility/subacute rehabilitation facility. In programs that do not offer these experiences, most chairs feel that this training should be included. In addition, study results suggest that most PM&R graduates work in an outpatient setting. Based on the results that chairs strongly feel the need for resident education in postacute care settings and that most graduates go on to practice in outpatient settings, there is a potential discordance for our current Centers of Medicare and Medicaid Services graduate medical education funding model being linked to the acute care setting.

  7. White House Office of the Vice President Announces New Memorandum of Understanding in Clinical Proteogenomics Between the United States and Australia | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The White House Office of the Vice President has announced the signing of three Memoranda of Understanding (MOUs) that will make available an unprecedented international dataset to advance cancer research and care.

  8. Evaluating Investments in Natural Gas Vehicles and Infrastructure for Your Fleet: Vehicle Infrastructure Cash-Flow Estimation -- VICE 2.0; Clean Cities, Energy Efficiency & Renewable Energy (EERE)

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, John

    2015-04-02

    Presentation by Senior Engineer John Gonzales on Evaluating Investments in Natural Gas Vehicles and Infrastructure for Your Fleet using the Vehicle Infrastructure Cash-flow Estimation (VICE) 2.0 model.

  9. The Investigation of Identity Construction: A Foucauldian Reading of Sam Shepard's Buried Child

    Directory of Open Access Journals (Sweden)

    Saeidabadi S.

    2016-01-01

    Full Text Available Shepard is peculiarly powerful in his symbolic family problem plays: True West, Buried Child and Curse of the Starving Class. He allegorizes the American experience and undermines the myth of America as the New Eden. The present study seeks to critically explore Sam Shepard's Buried Child in terms of Foucauldian conception of identity construction. Shepard is depicting a dystopian world with its bewildered characters; however he has still got a romantic view of individuals trying to grapple with the society in order to get unity and order. This Shephardian attitude towards human beings is seemingly a free agent that overlaps the Foucauldian view which establishes a philosophy focusing on the relationship between the self and the society. The present essay attempts to demonstrate the complicated relationship between the self and the opposing forces.

  10. SAGE I and SAM II measurements of 1 micron aerosol extinction in the free troposphere

    Science.gov (United States)

    Kent, G. S.; Farrukh, U. O.; Wang, P. H.; Deepak, A.

    1988-01-01

    The SAGE-I and SAM-II satellite sensors were designed to measure, with global coverage, the 1 micron extinction produced by the stratospheric aerosol. In the absence of high altitude clouds, similar measurements may be made for the free tropospheric aerosol. Median extinction values at middle and high latitudes in the Northern Hemisphere, for altitudes between 5 and 10 km, are found to be one-half to one order of magnitude greater than values at corresponding latitudes in the Southern Hemisphere. In addition, a seasonal increase by a factor of 1.5-2 was observed in both hemispheres, in 1979-80, in local spring and summer. Following major volcanic eruptions, a long-lived enhancement of the aerosol extinction is observed for altitudes above 5 km.

  11. SAGE 1 and SAM 2 measurements of 1 micron aerosol extinction in the free troposphere

    Science.gov (United States)

    Kent, G. S.; Farrukh, U. O.; Wang, P. H.; Deepak, A.

    1988-01-01

    The SAGE 1 and SAM 2 satellite sensors were designed to measure, with global coverage, the 1 micron extinction produced by the stratospheric aerosol. In the absence of high altitude cloud, similar measurements may be made for the free tropospheric aerosol. Median extinction values in the Northern Hemisphere, for altitudes between 5 and 10 km, are found to be one-half to one order of magnitude greater than values at corresponding latitudes in the Southern Hemisphere. In addition, a seasonal increase by a factor of 1.5 yields 2 is observed in both hemispheres in local spring and summer. Following major volcanic eruptions, a long-lived enhancement of the aerosol extinction is observed for altitudes above 5 km.

  12. Mechanistic Investigations of Lysine-Tryptophan Crosslink Formation Catalyzed by Streptococcal Radical SAM Enzymes.

    Science.gov (United States)

    Schramma, Kelsey R; Forneris, Clarissa C; Caruso, Alessio; Seyedsayamdost, Mohammad R

    2018-01-10

    Streptide is a ribosomally synthesized and post-translationally modified peptide with a unique cyclization motif consisting of an intramolecular lysine-tryptophan crosslink. Three radical SAM enzymes, StrB, AgaB, and SuiB from different Streptococci, have been shown to install this modification onto their respective precursor peptides in a leader-dependent fashion. Herein we conduct detailed investigations to differentiate between several plausible mechanistic proposals, specifically addressing radical versus electrophilic addition to the indole during crosslink formation, the role of substrate side-chains in binding in the enzyme active site, and the identity of the catalytic base in the reaction cycle. Our results are consistent with a radical electrophilic aromatic substitution mechanism for the key carbon-carbon bond-forming step. They also elaborate on other mechanistic features that underpin this unique and synthetically challenging post-translational modification.

  13. Sam Thompson, Stewart Parker, and the lineage of northern Irish drama

    Directory of Open Access Journals (Sweden)

    Marilynn Richtarik

    2010-11-01

    Full Text Available Northern Irish dramatist Stewart Parker (1941-1988 wrote plays typically valued for their wit, intellectual content, and formal experimentation. Nonetheless, he was profoundly influenced as a young man by a very different sort of playwright. Sam Thompson (1916-1965, who began his working life in the Belfast shipyards, squarely confronted Northern Irish sectarianism in his plays. His sense of the political potential of drama left an enduring mark on Parker, who organized and edited Thompson's manuscripts several years after his untimely death. Although their dramatic writings bear little resemblance to each other, the two writers should be regarded as united in a common Northern Irish dramatic tradition by virtue of their shared socialist outlook, belief in the importance of individual stands against conformity, and sense of theatre's social mission.

  14. Charge dependent asphaltene adsorption onto metal substrate : electrochemistry and AFM, STM, SAM, SEM analysis

    Energy Technology Data Exchange (ETDEWEB)

    Batina, N.; Morales-Martinez, J. [Univ. Autonoma Metropolitana-Iztapalapa (Mexico). Lab. de Nanotecnologia e Ingenieria Molecular; Ivar-Andersen, S. [Technical Univ. of Denmark (Denmark). Dept. Hem. Eng; Lira-Galeana, C. [Inst. Mexicano del Petroleo, Lazaro (Mexico). Molecular Simulation Research Program; De la Cruz-Hernandez, W.; Cota-Araiza, L.; Avalos-Borja, M. [Univ. Nacional Autonoma de Mexico (Mexico)

    2008-07-01

    Asphaltenes have been identified as the main component of pipeline molecular deposits that cause plugging of oil wells. In this study, Atomic Force Microscopy (AFM), Scanning Tunneling Microscopy (STM), Scanning Auger Microprobe Spectroscopy (SAM) and Scanning Electron Microscopy (SEM) were used to characterized molecular deposits of Mexican crude oil and asphaltenes formed at a charged metal surface. The qualitative and quantitative characterization involved determining the size and shape of adsorbed molecules and aggregates, and the elemental analysis of all components in molecular films. Samples were prepared by electrolytic deposition under galvanostatic or potentiostatic conditions directly from the crude oil or asphaltene in toluene solutions. The study showed that the formation of asphaltene deposit depends on the metal substrate charge. Asphaltenes as well as crude oil readily adsorbed at the negatively charged metal surface. Two elements were present, notably carbon and sulfur. Their content ratio varied depending on the metal substrate charge.

  15. Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain?

    Science.gov (United States)

    Mercurio, Flavia A; Costantini, Susan; Di Natale, Concetta; Pirone, Luciano; Guariniello, Stefano; Scognamiglio, Pasqualina L; Marasco, Daniela; Pedone, Emilia M; Leone, Marilisa

    2017-09-01

    Ephrin A2 receptor (EphA2) plays a key role in cancer, it is up-regulated in several types of tumors and the process of ligand-induced receptor endocytosis, followed by degradation, is considered as a potential path to diminish tumor malignancy. Protein modulators of this mechanism are recruited at the cytosolic Sterile alpha motif (Sam) domain of EphA2 (EphA2-Sam) through heterotypic Sam-Sam associations. These interactions engage the C-terminal helix of EphA2 and close loop regions (the so called End Helix side). In addition, several studies report on destabilizing mutations in EphA2 related to cataract formation and located in/or close to the Sam domain. Herein, we analyzed from a structural point of view, one of these mutants characterized by the insertion of a novel 39 residue long polypeptide at the C-terminus of EphA2-Sam. A 3D structural model was built by computational methods and revealed partial disorder in the acquired C-terminal tail and a few residues participating in an α-helix and two short β-strands. We investigated by CD and NMR studies the conformational properties in solution of two peptides encompassing the whole C-terminal tail and its predicted helical region, respectively. NMR binding experiments demonstrated that these peptides do not interact relevantly with either EphA2-Sam or its interactor Ship2-Sam. Molecular dynamics (MD) simulations further indicated that the EphA2 mutant could be represented only through a conformational ensemble and that the C-terminal tail should not largely wrap the EphA2-Sam End-Helix interface and affect binding to other Sam domains. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. «E-SCIENTROCHAIR»- ONLINE DATABASE FOR MANAGEMENT AND ASSESSMENT OF THE RESEARCH RESOURCES OF THE UNIVERSITY BASIS UNIT – THE CHAIR

    Directory of Open Access Journals (Sweden)

    MIHAI Florin

    2009-05-01

    Full Text Available The concept named e-ScientRoChair proposes searching for new informing and documentation opportunities, on fundamental structure in academic scientific research, meaning the chair or the research team, anabling the possibility to publish and as well as to

  17. How Academic Department Chairs View the Influence of Corporate Ethics Scandals on Ethics Education in Arizona Business Schools: A Qualitative Case Study at the Postsecondary Level

    Science.gov (United States)

    Gillis, Robert James

    2017-01-01

    The purpose of this qualitative single case study was to explore how department chairs described the influence of recent corporate ethics scandals on content and availability of ethics education in postsecondary business schools in Arizona. The following research questions guided this study: RQ1: How do department chairs describe the influence of…

  18. 77 FR 6536 - Approval for Manufacturing Authority; Foreign-Trade Zone 177; Best Chair, Inc., d/b/a Best Home...

    Science.gov (United States)

    2012-02-08

    ... Foreign-Trade Zones Board Approval for Manufacturing Authority; Foreign-Trade Zone 177; Best Chair, Inc., d/b/a Best Home Furnishings, Inc. (Upholstered Furniture); Ferdinand, Cannelton, and Paoli, IN..., grantee of Foreign-Trade Zone 177, has requested manufacturing authority on behalf of Best Chair, Inc., d...

  19. Boron (B) deprivation increases plasma homocysteine and decreases liver S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in rats

    Science.gov (United States)

    The diverse effects of B deprivation suggest that B affects a biomolecule involved in a variety of biochemical reactions. An experiment was conducted to determine whether dietary B affects the liver concentration of SAM, a frequently used enzyme substrate, especially for methylation reactions that y...

  20. Reactions Involving Calcium and Magnesium Sulfates as Potential Sources of Sulfur Dioxide During MSL SAM Evolved Gas Analyses

    Science.gov (United States)

    McAdam, A. C.; Knudson, C. A.; Sutter, B.; Franz, H. B.; Archer, P. D., Jr.; Eigenbrode, J. L.; Ming, D. W.; Morris, R. V.; Hurowitz, J. A.; Mahaffy, P. R.; hide

    2016-01-01

    The Sample Analysis at Mars (SAM) and Chemistry and Mineralogy (CheMin) instruments on the Mars Science Laboratory (MSL) have analyzed several subsamples of 860 C). Sulfides or Fe sulfates were detected by CheMin (e.g., CB, MJ, BK) and could contribute to the high temperature SO2 evolution, but in most cases they are not present in enough abundance to account for all of the SO2. This additional SO2 could be largely associated with x-ray amorphous material, which comprises a significant portion of all samples. It can also be attributed to trace S phases present below the CheMin detection limit, or to reactions which lower the temperatures of SO2 evolution from sulfates that are typically expected to thermally decompose at temperatures outside the SAM temperature range (e.g., Ca and Mg sulfates). Here we discuss the results of SAM-like laboratory analyses targeted at understanding this last possibility, focused on understanding if reactions of HCl or an HCl evolving phase (oxychlorine phases, chlorides, etc.) and Ca and Mg sulfates can result in SO2 evolution in the SAM temperature range.

  1. An Evaluation and Development Environment for an ARM7-Based Autopilot Using the Atmel SAM7S256 Microcontroller

    Science.gov (United States)

    2009-08-01

    size. These microcontrollers provide more computational ability than smaller Microchip peripheral interface controllers or AVR microcontrollers , while...An Evaluation and Development Environment for an ARM7-Based Autopilot Using the Atmel SAM7S256 Microcontroller by Justin L. Shumaker and... Microcontroller Justin L. Shumaker Vehicle Technology Directorate, ARL Ainsmar X. Brown National Institute of Aerospace

  2. Vejsalg, gårdbutikker og fritidsfiskere - den informelle økonomi på Samsø

    DEFF Research Database (Denmark)

    Rasmussen, Rasmus Ole

    2007-01-01

    Bidraget behandler den uformelle økonomi på Samsø, med udgangspunkt i den første kortlægning nogensinde af den del af den uformelle økonomi som er forbundet med salg af produkter som er relaterede til naturgrundlaget. De mange vejboder er et iøjnefaldende element i landskabet, og nogle af dem har...

  3. Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

    DEFF Research Database (Denmark)

    Giessing, Anders; Jensen, Søren Skov; Rasmussen, Anette

    2009-01-01

    ,8-dimethyladenosine. The mutation of single conserved cysteine residues in the radical SAM motif CxxxCxxC of Cfr abolishes its activity, lending support to the notion that the Cfr modification reaction occurs via a radical-based mechanism. Antibiotic susceptibility data confirm that the antibiotic resistance...

  4. Response of Antarctic ice shelf melt to SAM trend and possible feedbacks with the ice-dynamics

    Science.gov (United States)

    Donat-Magnin, Marion; Jourdain, Nicolas C.; Gallée, Hubert; Spence, Paul; Cornford, Stephen L.; Le Sommer, Julien; Durand, Gaël

    2017-04-01

    The observed positive trend in the Southern Annular Mode (SAM) may warm the Southern Ocean sub-surface through decreased Ekman downward pumping. Subsequent change in ice-shelves melt has been suggested to trigger glacier acceleration in West Antarctica. Here we use a regional ocean model configuration of the Amundsen Sea that includes interactive ice-shelf cavities. Our results show that the inclusion of ice-shelves changes the ocean response to the projected SAM trend, i.e. it typically inhibits a part of the SAM-induced subsurface warming. Heat budget analysis has been used to propose responsible mechanisms. Regarding Thwaites and Pine Island, sub ice-shelf melt increases above 400m by approximately 40% for Thwaites and 10% for Pine Island and decreases by up to 10% below in response to ocean temperature changes driven by the projected SAM trend. The melt sensitivity to poleward shifting winds is nonetheless small compared to the sensitivity to an ice-sheet instability, i.e. to a projected change in the shape of ice-shelf cavities. For instance, the sub ice-shelf melt are doubled near the grounding line of some glaciers in response to the largest grounding line retreat projected for 2100. Large increase in basal melt close to the grounding line could largely impact instability and glacier acceleration. Our work suggests the need for including ice shelves into ocean models, and to couple ocean models to ice-sheet models in climate projections.

  5. Carbon and Sulfur Isotopic Composition of Yellowknife Bay Sediments: Measurements by the Sample Analysis at Mars (SAM) Quadrupole Mass Spectrometer

    Science.gov (United States)

    Franz, H. B.; Mahaffy, P. R.; Stern, J. C.; Eigenbrode, J. L.; Steele, A.; Ming, D. W.; McAdam, A. C.; Freissinet, C.; Glavin, D. P.; Archer, P. D.; hide

    2014-01-01

    Since landing at Gale Crater in Au-gust 2012, the Sample Analysis at Mars (SAM) instru-ment suite on the Mars Science Laboratory (MSL) “Curiosity” rover has analyzed solid samples from the martian regolith in three locations, beginning with a scoop of aeolian deposits from the Rocknest (RN) sand shadow. Curiosity subsequently traveled to Yellowknife Bay, where SAM analyzed samples from two separate holes drilled into the Sheepbed Mudstone, designated John Klein (JK) and Cumberland (CB). Evolved gas analysis (EGA) of all samples revealed the presence of H2O as well as O-, C- and S-bearing phas-es, in most cases at abundances below the detection limit of the CheMin instrument. In the absence of definitive mineralogical identification by CheMin, SAM EGA data can help provide clues to the mineralogy of volatile-bearing phases through examination of tem-peratures at which gases are evolved from solid sam-ples. In addition, the isotopic composition of these gas-es may be used to identify possible formation scenarios and relationships between phases. Here we report C and S isotope ratios for CO2 and SO2 evolved from the JK and CB mudstone samples as measured with SAM’s quadrupole mass spectrometer (QMS) and draw com-parisons to RN.

  6. Optimisation and Characterisation of Anti-Fouling Ternary SAM Layers for Impedance-Based Aptasensors

    Directory of Open Access Journals (Sweden)

    Anna Miodek

    2015-09-01

    Full Text Available An aptasensor with enhanced anti-fouling properties has been developed. As a case study, the aptasensor was designed with specificity for human thrombin. The sensing platform was developed on screen printed electrodes and is composed of a self-assembled monolayer made from a ternary mixture of 15-base thiolated DNA aptamers specific for human thrombin co-immobilised with 1,6-hexanedithiol (HDT and further passivated with 1-mercapto-6-hexanol (MCH. HDT binds to the surface by two of its thiol groups forming alkyl chain bridges and this architecture protects from non-specific attachment of molecules to the electrode surface. Using Electrochemical Impedance Spectroscopy (EIS, the aptasensor is able to detect human thrombin as variations in charge transfer resistance (Rct upon protein binding. After exposure to a high concentration of non-specific Bovine Serum Albumin (BSA solution, no changes in the Rct value were observed, highlighting the bio-fouling resistance of the surface generated. In this paper, we present the optimisation and characterisation of the aptasensor based on the ternary self-assembled monolayer (SAM layer. We show that anti-fouling properties depend on the type of gold surface used for biosensor construction, which was also confirmed by contact angle measurements. We further studied the ratio between aptamers and HDT, which can determine the specificity and selectivity of the sensing layer. We also report the influence of buffer pH and temperature used for incubation of electrodes with proteins on detection and anti-fouling properties. Finally, the stability of the aptasensor was studied by storage of modified electrodes for up to 28 days in different buffers and atmospheric conditions. Aptasensors based on ternary SAM layers are highly promising for clinical applications for detection of a range of proteins in real biological samples.

  7. 24 February 2012 - Polish Vice-Rectors AGH University of Science and Technology Cracow visiting the ATLAS underground experimental area with Former Collaboration Spokesperson P. Jenni; Vice Rector J. Lis signs a collaboration agreement with A. Unnervik; Adviser T. Kurtyka and A. Siemko accompany the delegation throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    24 February 2012 - Polish Vice-Rectors AGH University of Science and Technology Cracow visiting the ATLAS underground experimental area with Former Collaboration Spokesperson P. Jenni; Vice Rector J. Lis signs a collaboration agreement with A. Unnervik; Adviser T. Kurtyka and A. Siemko accompany the delegation throughout.

  8. Adjoint(e) de direction à la Vice-présidente, Stratégie générale et ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Résumé des fonctions Sous la direction de la vice-présidente, Stratégie générale et communications, et relevant du conseiller principal en stratégie et communications, l'adjoint de direction fournit de l'appui en secrétariat et en administration au BVP-SGC, et en particulier à la vice présidente, procurant un vaste éventail de ...

  9. School Desk and Chair Design Based on High School Female Students Anthropometry Qazvin, Iran 2007 to 2008

    Directory of Open Access Journals (Sweden)

    S Varmazyar

    2012-05-01

    Full Text Available

    Background and Objectives

    Anthropometry data compiled from body dimensions of female high school students are used to optimize the design of desks and chairs for the classrooms of these students. It is necessary to design suitable desk/chair based on anthropometry data in order to reduce musculoskeletal, visual, circulatory problems, and bad posture during long hours of studying.

    The goal of this study is to design desks/chairs based on the standard BS 5873 using the body dimensions of 240 female high school students.

     

    Methods

    240 female students, between the ages of 15 to 17 years old were selected from six different high schools in district 2 of city of Qazvin in Iran. Data for this study were gathered using an interview method and anthropometry measurement devices.

     

    Results

    Eighteen body dimension parameters of 240 female high school students were obtained. The collected data were analyzed and compared to the standard using SPSS methods. The participant students were divided into 2 groups and customized desk/chair designs were built to fit their body dimensions. 

     

    Conclusion

    There is a significant difference between each customized desk and chair dimension, and standard dimensions used in the industry with an exception of the heights of these designs. We suggest that customized designs based on body dimensions promote correct posture, comfort and health.

  10. The expression platform and the aptamer: cooperativity between Mg2+ and ligand in the SAM-I riboswitch

    Science.gov (United States)

    Hennelly, Scott P.; Novikova, Irina V.; Sanbonmatsu, Karissa Y.

    2013-01-01

    Riboswitch operation involves the complex interplay between the aptamer domain and the expression platform. During transcription, these two domains compete against each other for shared sequence. In this study, we explore the cooperative effects of ligand binding and Magnesium interactions in the SAM-I riboswitch in the context of aptamer collapse and anti-terminator formation. Overall, our studies show the apo-aptamer acts as (i) a pre-organized aptamer competent to bind ligand and undergo structural collapse and (ii) a conformation that is more accessible to anti-terminator formation. We show that both Mg2+ ions and SAM are required for a collapse transition to occur. We then use competition between the aptamer and expression platform for shared sequence to characterize the stability of the collapsed aptamer. We find that SAM and Mg2+ interactions in the aptamer are highly cooperative in maintaining switch polarity (i.e. aptamer ‘off-state’ versus anti-terminator ‘on-state’). We further show that the aptamer off-state is preferentially stabilized by Mg2+ and similar divalent ions. Furthermore, the functional switching assay was used to select for phosphorothioate interference, and identifies potential magnesium chelation sites while characterizing their coordinated role with SAM in aptamer stabilization. In addition, we find that Mg2+ interactions with the apo-aptamer are required for the full formation of the anti-terminator structure, and that higher concentrations of Mg2+ (>4 mM) shift the equilibrium toward the anti-terminator on-state even in the presence of SAM. PMID:23258703

  11. Developing the principles of chair based exercise for older people: a modified Delphi study.

    Science.gov (United States)

    Robinson, Katie R; Leighton, Paul; Logan, Philippa; Gordon, Adam L; Anthony, Kevin; Harwood, Rowan H; Gladman, John R F; Masud, Tahir

    2014-05-19

    Chair based exercise (CBE) is suggested to engage older people with compromised health and mobility in an accessible form of exercise. A systematic review looking at the benefits of CBE for older people identified a lack of clarity regarding a definition, delivery, purpose and benefits. This study aimed to utilise expert consensus to define CBE for older people and develop a core set of principles to guide practice and future research. The framework for consensus was constructed through a team workshop identifying 42 statements within 7 domains. A four round electronic Delphi study with multi-disciplinary health care experts was undertaken. Statements were rated using a 5 point Likert scale of agreement and free text responses. A threshold of 70% agreement was used to determine consensus. Free text responses were analysed thematically. Between rounds a number of strategies (e.g., amended wording of statements, generation and removal of statements) were used to move towards consensus. 16 experts agreed on 46 statements over four rounds of consultation (Round 1: 22 accepted, 3 removed, 5 new and 17 modified; Round 2: 16 accepted, 0 removed, 4 new and 6 modified; Round 3: 4 accepted, 2 removed, 0 new and 4 modified; Round 4: 4 accepted, 0 removed, 0 new, 0 modified).Statements were accepted in all seven domains: the definition of CBE (5), intended users (3), potential benefits (8), structure (12), format (8), risk management (7) and evaluation (3).The agreed definition of CBE had five components: 1. CBE is primarily a seated exercise programme; 2. The purpose of using a chair is to promote stability in both sitting and standing; 3. CBE should be considered as part of a continuum of exercise for frail older people where progression is encouraged; 4. CBE should be used flexibly to respond to the changing needs of frail older people; and 5. Where possible CBE should be used as a starting point to progress to standing programmes. Consensus has been reached on a definition

  12. Astronomy from the chair - the application of the Internet in promoting of Astronomy

    Science.gov (United States)

    Tomic, Zoran

    2014-05-01

    Internet and modern communication technologies are an indispensable part of modern life. The use of the Internet makes it possible to enhance the education and expand opportunities for acquiring new knowledge. One example is Astronomy, where today thanks to the Internet, we can control telescopes that are distant from us and listen to lectures from Universities in other countries. "Astronomy from the chair" is the name for a concept where amateur astronomers can deal with astronomy from their homes using the Internet. The concept can be divided into four sections depending on the content being offered: Robotic Observatory, Virtual Observatory, Online astronomy broadcasting and Online courses. Robotic observatory is defined as an astronomical instrument and detection system that enables efficient observation without the need of a person's physical intervention. Virtual Observatory is defined as a collection of databases and software tools that use the Internet as a platform for scientific research. Online astronomy broadcasting is part of concept "Astronomy from the chair" which gives users the opportunity to get directly involved in astronomical observation organized by an amateur astronomer from somewhere in the world. Online courses are groups of sites and organizations that provide the opportunity to amateur astronomers to attend lectures, save and watch video materials from lectures, do homework, communicate with other seminar participants and in that way become familiar with the various areas of Astronomy. This paper discusses a new concept that describes how the Internet can be applied in modern education. In this paper will be described projects that allows a large number of astronomy lovers to do their own research without the need to own a large and expensive set of astronomical equipment (Virtual Telescope from Italy, Observatory "Night Hawk" from Serbia and project "Astronomy from an armchair" at Faculty of Sciences and Mathematics in Nis), to help

  13. Vibrational Stark Effect of the Electric-Field Reporter 4-Mercaptobenzonitrile as a Tool for Investigating Electrostatics at Electrode/SAM/Solution Interfaces

    Directory of Open Access Journals (Sweden)

    Peter Hildebrandt

    2012-06-01

    Full Text Available 4-mercaptobenzonitrile (MBN in self-assembled monolayers (SAMs on Au and Ag electrodes was studied by surface enhanced infrared absorption and Raman spectroscopy, to correlate the nitrile stretching frequency with the local electric field exploiting the vibrational Stark effect (VSE. Using MBN SAMs in different metal/SAM interfaces, we sorted out the main factors controlling the nitrile stretching frequency, which comprise, in addition to external electric fields, the metal-MBN bond, the surface potential, and hydrogen bond interactions. On the basis of the linear relationships between the nitrile stretching and the electrode potential, an electrostatic description of the interfacial potential distribution is presented that allows for determining the electric field strengths on the SAM surface, as well as the effective potential of zero-charge of the SAM-coated metal. Comparing this latter quantity with calculated values derived from literature data, we note a very good agreement for Au/MBN but distinct deviations for Ag/MBN which may reflect either the approximations and simplifications of the model or the uncertainty in reported structural parameters for Ag/MBN. The present electrostatic model consistently explains the electric field strengths for MBN SAMs on Ag and Au as well as for thiophenol and mercaptohexanoic acid SAMs with MBN incorporated as a VSE reporter.

  14. Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.

    Science.gov (United States)

    Rothé, Benjamin; Leettola, Catherine N; Leal-Esteban, Lucia; Cascio, Duilio; Fortier, Simon; Isenschmid, Manuela; Bowie, James U; Constam, Daniel B

    2017-12-26

    Head-to-tail polymers of sterile alpha motifs (SAM) can scaffold large macromolecular complexes. Several SAM-domain proteins that bind each other are mutated in patients with cystic kidneys or laterality defects, including the Ankyrin (ANK) and SAM domain-containing proteins ANKS6 and ANKS3, and the RNA-binding protein Bicc1. To address how their interactions are regulated, we first determined a high-resolution crystal structure of a Bicc1-SAM polymer, revealing a canonical SAM polymer with a high degree of flexibility in the subunit interface orientations. We further mapped interactions between full-length and distinct domains of Bicc1, ANKS3, and ANKS6. Neither ANKS3 nor ANKS6 alone formed macroscopic homopolymers in vivo. However, ANKS3 recruited ANKS6 to Bicc1, and the three proteins together cooperatively generated giant macromolecular complexes. Thus, the giant assemblies are shaped by SAM domains, their flanking sequences, and SAM-independent protein-protein and protein-mRNA interactions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Mechanography in childhood: references for force and power in counter movement jumps and chair rising tests.

    Science.gov (United States)

    Busche, P; Rawer, R; Rakhimi, N; Lang, I; Martin, D D

    2013-06-01

    We sought to procure age- and gender- related reference data and study the characteristics of body weight related peak force (pFrel), body mass related peak power (pPrel) for counter movement jumps (single two-legged jumps, s2LJ) and chair rising tests (CRT) in children. We examined 868 healthy participants (436 female) aged 3 to 19 years. Weight-related results of the s2LJ and CRT Mechanography parameters were reported. pPrel during s2LJ (pPrel(s2LJ)) increased linearly with age for males age 5 to 19 and female age 5 to 11 at a rate of 4.6 W/kg per year. pPrel(s2LJ) for females age 12 to 19 increased only by 2.5 W/kg. CRT time per repetition was 1.065 s, independent of age and gender. pPrel per body mass during the rise phase (pPrel(CRT)) showed similar but smaller age and gender relations as peak power during s2LJ. pFrel was 2.5 g (multiples of earth's gravity) for s2LJ and 1.5 g for CRT. This data from normal children from a healthy Caucasian population provide reference values for tests that reflect everyday motor function.

  16. Faculty Hiring and Development at BYU: Perspectives of a Recent Hire and Department Chair

    Science.gov (United States)

    Turley, R. Steven

    2002-04-01

    I will present a personal perspective on the transition from an industrial to an academic physicist. For those planning on a similar transition, I will mention several things that were helpful in preparing myself, marketing myself, and adapting to an academic setting. For instance, a significant difference between academic and industrial physics is the responsibility of classroom teaching. Several things that proved particularly useful in improving my own teaching were mentoring teaching partnerships, student evaluations, help in the tenure and promotion process, and programs available from our Faculty Center. From my current perspective as a department chair, I will further discuss mentoring practices I have found helpful with other new faculty. These include such things as inviting mentors to participate with new faculty in development workshops and providing financial and other recognition for participation as a mentor. In addition to developing professional skills, I have found that good mentoring is particularly critical in encouraging new faculty to adapt to departmental culture. Finally, I will discuss ideas I have found helpful in successfully recruiting new faculty. This involves researching, identifying, and actively recruiting faculty we think will build our department. For us, it has not been sufficient to passively rely on responses from applicants to advertisements and word-of-mouth inquiries. Through careful hiring and effective mentoring, we have developed an excellent record of having our faculty being successful in the tenure process.

  17. Do institutional logics predict interpretation of contract rules at the dental chair-side?

    Science.gov (United States)

    Harris, Rebecca; Brown, Stephen; Holt, Robin; Perkins, Elizabeth

    2014-12-01

    In quasi-markets, contracts find purchasers influencing health care providers, although problems exist where providers use personal bias and heuristics to respond to written agreements, tending towards the moral hazard of opportunism. Previous research on quasi-market contracts typically understands opportunism as fully rational, individual responses selecting maximally efficient outcomes from a set of possibilities. We take a more emotive and collective view of contracting, exploring the influence of institutional logics in relation to the opportunistic behaviour of dentists. Following earlier qualitative work where we identified four institutional logics in English general dental practice, and six dental contract areas where there was scope for opportunism; in 2013 we surveyed 924 dentists to investigate these logics and whether they had predictive purchase over dentists' chair-side behaviour. Factor analysis involving 300 responses identified four logics entwined in (often technical) behaviour: entrepreneurial commercialism, duty to staff and patients, managerialism, public good. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. State Space Composition Technique for Intelligent Wheel Chair Adapting to Environment.

    Science.gov (United States)

    Hamagami, Tomoki; Hirata, Hironori

    This paper describes a state space composition technique for the adaptation to environment in the autonomous behavior of intelligent wheel chair (IWC).In the product like IWC with actual sensors, composing state space is difficult problem since environmental information can not be observed sufficiently from restricted sensor inputs.A lot of states observed from same environment position raise the fail of the learning and adaptation with active learning approach.In order to compensate for the effects of the sensor configuration, that is sensor position, angle and precision, a normalization processing of position detector is introduced.In sensor normalization process, IWC scans present environment via range sensors with executing spot-turn, and prepare scan-patterns of each sensor.Then the normalization process adjusts the phase and dynamic range of each pattern to the reference sensor scan-pattern, analyzing phase differences and scale factors of each pattern against reference pattern.Using phase difference and scale factors, automated state space composition is possible.From the simulation experiment with both artificial and real-worlddraft, the automated state space construction is confirmed as a practical approach for pre-processing for environment learning and adaptation.

  19. [THE FOUNDERS OF FIRST CHAIRS OF HISTORY OF MEDICINE AND SOCIAL HYGIENE IN THE USSR].

    Science.gov (United States)

    Gorelova, L E; Kasimovskaia, N A

    2015-01-01

    The USSR academy of medical sciences was organized in 1944. At the same year, the institute of health care organization, medical statistics and social hygiene was included in its structure. Before the institute global tasks in area of research and pedagogic activities were stated. They were implemented in accordance with actual national demands. The institute became a leading research center of studying problems of population health, social hygiene, organization and management of health care and history of medicine. In 2003, the institute was renamed in the The RAMS national research institute of public health, and in 2013 was handed over the Federal agency of research organizations (FANO) of Russia. The directors of the institute were well-known scientists in the field of social hygiene health care organization and history of medicine. They made a significant input into development of medical education, combining scientific, managerial and pedagogic activities. The founders of the first chairs of history of medicine and social hygiene were the directors of the institute I.D. Strashun and N.A. Semashko.

  20. Does using an ejector chair affect muscle activation patterns in rheumatoid arthritic patients? A preliminary investigation.

    Science.gov (United States)

    Munro, B J; Steele, J R

    2000-02-01

    The present study examined knee and arm extensor muscle activation patterns displayed by 12 elderly female rheumatoid arthritic patients (mean age = 65.5 +/- 8.6 yr) rising from an instrumented Eser ejector chair under four conditions: high seat (540 mm), low seat (450 mm), with and without ejector assistance. Electromyographic (EMG) signals were sampled (1000 Hz) for vastus lateralis (VL), vastus medialis (VM), rectus femoris (RF) and triceps brachii (TB) using a Noraxon Telemyo System (bandwidth 0-340 Hz). Muscle onset, offset and peak activity relative to loss of seat contact (SS), and integrated EMG, were calculated for each muscle burst before SS. A high seat significantly (p Ejector assistance significantly increased VM and RF burst duration and RF intensity but had no effect on vastii muscle intensity. It was concluded that concerns pertaining to muscle disuse when rising with ejector assistance were unfounded in the present study. However, further research is required to investigate the effects of habitual use of a mechanical ejector device on muscle activation patterns.

  1. Rocking-Chair Ammonium-Ion Battery: A Highly Reversible Aqueous Energy Storage System.

    Science.gov (United States)

    Wu, Xianyong; Qi, Yitong; Hong, Jessica J; Li, Zhifei; Hernandez, Alexandre S; Ji, Xiulei

    2017-10-09

    Aqueous rechargeable batteries are promising solutions for large-scale energy storage. Such batteries have the merit of low cost, innate safety, and environmental friendliness. To date, most known aqueous ion batteries employ metal cation charge carriers. Here, we report the first "rocking-chair" NH4 -ion battery of the full-cell configuration by employing an ammonium Prussian white analogue, (NH4 )1.47 Ni[Fe(CN)6 ]0.88 , as the cathode, an organic solid, 3,4,9,10-perylenetetracarboxylic diimide (PTCDI), as the anode, and 1.0 m aqueous (NH4 )2 SO4 as the electrolyte. This novel aqueous ammonium-ion battery demonstrates encouraging electrochemical performance: an average operation voltage of ca. 1.0 V, an attractive energy density of ca. 43 Wh kg(-1) based on both electrodes' active mass, and excellent cycle life over 1000 cycles with 67 % capacity retention. Importantly, the topochemistry results of NH4(+) in these electrodes point to a new paradigm of NH4(+) -based energy storage. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Machining variability impacts on the strength of a 'chair-side' CAD-CAM ceramic.

    Science.gov (United States)

    Addison, Owen; Cao, Xu; Sunnar, Parminder; Fleming, Garry J P

    2012-08-01

    To develop a novel methodology to generate specimens for bi-axial flexure strength (BFS) determination from a 'chair-side' CAD-CAM feldspathic ceramic with surface defect integrals analogous to the clinical state. The hypotheses tested were: BFS and surface roughness (R(a)) are independent of machining variability introduced by the renewal or deterioration of form-grinding tools and that a post-machining annealing cycle would significantly modify BFS. Nominally identical disc-shaped specimens (11 mm diameter, 1.1mm thickness) were machined with identical design and operative parameters from Vita Mark II feldspathic ceramic. Six individual bur sets (Groups A-F) generated 14 specimens each. Three groups were annealed between glass transition and softening temperatures. 3D contact profilometry determined surface roughness before and following annealing and prior to BFS determination. Scanning electron microscopy was undertaken to examine machining tools and perform fractographic analyses of ceramic fracture fragments. Statistical analysis included independent and pairwise analyses of R(a)-values (Pmachining order and BFS or R(a) were observed (P>0.05). Surface roughness and the nature of strength limiting defects appear to be probabilistic with flaw generation dependent on a random selection of a bur and a random machining sequence. The variability in BFS with machining could account for premature clinical failures. Copyright © 2012 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  3. The influence of basic ventilation strategies and anesthetic techniques on cerebral oxygenation in the beach chair position: study protocol

    Directory of Open Access Journals (Sweden)

    Picton Paul

    2012-09-01

    Full Text Available Abstract Background Beach chair positioning during general anesthesia is associated with a high incidence of cerebral desaturation; poor neurological outcome is a growing concern. There are no published data pertaining to changes in cerebral oxygenation seen with increases in the inspired oxygen fraction or end-tidal carbon dioxide in patients anesthetized in the beach chair position. Furthermore, the effect anesthetic agents have has not been thoroughly investigated in this context. We plan to test the hypothesis that changes in inspired oxygen fraction or end-tidal carbon dioxide correlate to a significant change in regional cerebral oxygenation in anesthetized patients in beach chair position. We will also compare the effects that inhaled and intravenous anesthetics have on this process. Methods/design This is a prospective within-group study of patients undergoing shoulder arthroscopy in the beach chair position which incorporates a randomized comparison between two anesthetics, approved by the Institutional Review Board of the University of Michigan, Ann Arbor. The primary outcome measure is the change in regional cerebral oxygenation due to sequential changes in oxygenation and ventilation. A sample size of 48 will have greater than 80% power to detect an absolute 4-5% difference in regional cerebral oxygenation caused by changes in ventilation strategy. The secondary outcome is the effect of anesthetic choice on cerebral desaturation in the beach chair position or response to changes in ventilation strategy. Fifty-four patients will be recruited, allowing for drop out, targeting 24 patients in each group randomized to an anesthetic. Regional cerebral oxygenation will be measured using the INVOS 5100C monitor (Covidien, Boulder, CO. Following induction of anesthesia, intubation and positioning, inspired oxygen fraction and minute ventilation will be sequentially adjusted. At each set point, regional cerebral oxygenation will be recorded

  4. Combining food type(s) and food quantity choice in a new food choice paradigm based on vice-virtue bundles.

    Science.gov (United States)

    Haws, Kelly L; Liu, Peggy J

    2016-08-01

    Given the prevalence and rising rates of obesity in many countries, including the United States, much food decision-making research ultimately aims at understanding how consumers can make healthier choices. The two predominant choice paradigms used in food decision-making research ask consumers to choose (a) between a "vice" (or unhealthy food) and a "virtue" (or healthy food) or (b) among varying portion sizes of "vice." We propose a new food choice paradigm that encourages consumers to jointly consider both food type(s) choice and food portion size at each decision point. The purpose of this paradigm is two-fold. First, it aims to allow examination of more comprehensive eating behavior (e.g., to examine the overall composition of a plate of food rather than choice of a single food). Second, it aims to shift consumers towards including large proportions of virtues and smaller proportions of vice in their overall consumption portfolios. For this paradigm, we draw upon a recently introduced food product innovation called "vice-virtue bundles" (Liu et al., 2015) that illustrates the basis of this new food choice paradigm, in which food type(s) and portion decisions are made simultaneously. Accordingly, we first discuss relevant findings on vice-virtue bundles as well as the differences between simultaneous and sequential choice of multiple products. Second, we examine the benefits for managing and controlling one's consumption that are provided by vice-virtue bundles and this joint food choice paradigm more generally. Third and finally, we point out opportunities for future research by discussing (a) multiple factors that influence food choices, (b) decision processes affected by food choice paradigms, and (c) issues of generalizability related to the presence of vice-virtue bundles. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells

    Directory of Open Access Journals (Sweden)

    Koike Chieko

    2006-03-01

    Full Text Available Abstract Background Sterile alpha motif (SAM domains are ~70 residues long and have been reported as common protein-protein interaction modules. This domain is found in a large number of proteins, including Polycomb group (PcG proteins and ETS family transcription factors. In this work, we report the cloning and functional characterization of a novel SAM domain-containing protein, which is predominantly expressed in retinal photoreceptors and the pineal gland and is designated mouse mr-s (major retinal SAM domain protein. Results mr-s is evolutionarily conserved from zebrafish through human, organisms through which the mechanism of photoreceptor development is also highly conserved. Phylogenetic analysis suggests that the SAM domain of mr-s is most closely related to a mouse polyhomeotic (ph ortholog, Mph1/Rae28, which is known as an epigenetic molecule involved in chromatin modifications. These findings provide the possibility that mr-s may play a critical role by regulating gene expression in photoreceptor development. mr-s is preferentially expressed in the photoreceptors at postnatal day 3–6 (P3-6, when photoreceptors undergo terminal differentiation, and in the adult pineal gland. Transcription of mr-s is directly regulated by the cone-rod homeodomain protein Crx. Immunoprecipitation assay showed that the mr-s protein self-associates mainly through the SAM domain-containing region as well as ph. The mr-s protein localizes mainly in the nucleus, when mr-s is overexpressed in HEK293T cells. Moreover, in the luciferase assays, we found that mr-s protein fused to GAL4 DNA-binding domain functions as a transcriptional repressor. We revealed that the repression activity of mr-s is not due to a homophilic interaction through its SAM domain but to the C-terminal region. Conclusion We identified a novel gene, mr-s, which is predominantly expressed in retinal photoreceptors and pineal gland. Based on its expression pattern and biochemical analysis

  6. Chair rising exercise is more effective than one-leg standing exercise in improving dynamic body balance: a randomized controlled trial.

    Science.gov (United States)

    Yamashita, F; Iwamoto, J; Osugi, T; Yamazaki, M; Takakuwa, M

    2012-06-01

    A randomized controlled trial was conducted to compare the effect of a one-leg standing exercise and a chair-rising exercise on body balance in patients with locomotive disorders. Thirty ambulatory patients (mean age: 66.6 years) were randomly divided into two groups (n=15 in each group): a one-leg standing exercise group and a chair-rising exercise group. All the participants performed calisthenics of the major muscles, a tandem gait exercise, and a stepping exercise. The exercises were performed 3 days per week, and the study period was 5 months. Physical function was evaluated at baseline and at one-month intervals. No significant differences in the baseline characteristics were observed between the two groups. After the 5-month exercise program, the timed up and go, one-leg standing time, and tandem gait time improved significantly in the one-leg standing exercise group, while the walking time and chair-rising time in addition to above parameters improved significantly in the chair-rising exercise group. The improvements in the walking time, chair-rising time, and tandem gait time were significantly greater in the chair-rising exercise group than in the one-leg standing exercise group. The present study showed that the chair-rising exercise was more effective than the one-leg standing exercise for improving walking velocity and dynamic body balance.

  7. Evaluating Abdominal and Lower-Back Muscle Activity While Performing Core Exercises on a Stability Ball and a Dynamic Office Chair.

    Science.gov (United States)

    Holmes, Michael W R; De Carvalho, Diana E; Karakolis, Thomas; Callaghan, Jack P

    2015-11-01

    The purpose of this study was to evaluate the ability of a dynamic office chair to activate the core muscles while participants performed exercises sitting on the chair compared to a stability ball. Prolonged sitting has become an accepted part of the modern office. However, epidemiological evidence suggests that sedentary postures are linked to many adverse effects on health. The concept of dynamic or active sitting is intended to promote movement while sitting to reduce the time spent in prolonged, static postures. Sixteen participants performed four pelvic rotation exercises (front-back, side-side, circular, and leg lift) on both a dynamic office chair and a stability ball. Muscle activity from 12 torso muscles were evaluated with surface electromyography. For all exercises, trunk muscle activity on the chair was comparable to that on a stability ball. The right external oblique was the only muscle to produce greater peak activity (p = .019) when using the ball compared to the chair (21.4 ± 14.0 percent maximal voluntary excitations (%MVE) and 14.7 ± 10.8 %MVE for the ball and chair, respectively). The left thoracic erector spinae produced greater average activity (p = .044) on the chair than on the ball. These findings suggest that this dynamic sitting approach could be an effective tool for core muscle activation while promoting movement and exercise while sitting at work. Muscle activations on the dynamic chair are comparable to those on a stability ball, and dynamic office chairs can promote movement and exercise while sitting at work. © 2015, Human Factors and Ergonomics Society.

  8. A question of merit: John Hutton Balfour, Joseph Hooker and the 'concussion' over the Edinburgh chair of botany.

    Science.gov (United States)

    Bellon, Richard

    2005-03-01

    In 1845, Robert Graham's death created a vacancy for the traditionally dual appointment to the University of Edinburgh's chair of botany and the Regius Keepership of the Edinburgh Royal Botanic Garden. John Hutton Balfour and Joseph Hooker emerged as the leading candidates. The contest quickly became embroiled in long running controversies over the nature and control of Scottish university education at a time of particular social and political tension after a recent schism in Church of Scotland. The politics of the appointment were complicated by the fact that the Edinburgh Town Council (which preferred Balfour) chose the chair while the keepership was under the patronage of the Westminster government (which preferred Hooker). Balfour eventually emerged triumphant after a bitter campaign marked on all sides by intense politicking. The struggle to replace Graham provides a case study in how Victorian men of science adapted their aspirations to the practical realities of life in industrial, reforming, imperial, multinational Britain.

  9. A replicated field intervention study evaluating the impact of a highly adjustable chair and office ergonomics training on visual symptoms☆

    Science.gov (United States)

    Menéndez, Cammie Chaumont; Amick, Benjamin C.; Robertson, Michelle; Bazzani, Lianna; DeRango, Kelly; Rooney, Ted; Moore, Anne

    2016-01-01

    Objective Examine the effects of two office ergonomics interventions in reducing visual symptoms at a private sector worksite. Methods A quasi-experimental study design evaluated the effects of a highly adjustable chair with office ergonomics training intervention (CWT group) and the training only (TO group) compared with no intervention (CO group). Data collection occurred 2 and 1 month(s) pre-intervention and 2, 6 and 12 months post-intervention. During each data collection period, a work environment and health questionnaire (covariates) and daily health diary (outcomes) were completed. Multilevel statistical models tested hypotheses. Results Both the training only intervention (p ergonomics training alone and coupled with a highly adjustable chair reduced visual symptoms. In replicating results from a public sector worksite at a private sector worksite the external validity of the interventions is strengthened, thus broadening its generalizability. PMID:22030069

  10. A replicated field intervention study evaluating the impact of a highly adjustable chair and office ergonomics training on visual symptoms.

    Science.gov (United States)

    Menéndez, Cammie Chaumont; Amick, Benjamin C; Robertson, Michelle; Bazzani, Lianna; DeRango, Kelly; Rooney, Ted; Moore, Anne

    2012-07-01

    Examine the effects of two office ergonomics interventions in reducing visual symptoms at a private sector worksite. A quasi-experimental study design evaluated the effects of a highly adjustable chair with office ergonomics training intervention (CWT group) and the training only (TO group) compared with no intervention (CO group). Data collection occurred 2 and 1 month(s) pre-intervention and 2, 6 and 12 months post-intervention. During each data collection period, a work environment and health questionnaire (covariates) and daily health diary (outcomes) were completed. Multilevel statistical models tested hypotheses. Both the training only intervention (pergonomics training alone and coupled with a highly adjustable chair reduced visual symptoms. In replicating results from a public sector worksite at a private sector worksite the external validity of the interventions is strengthened, thus broadening its generalizability. Published by Elsevier Ltd.

  11. The effects of an office ergonomics training and chair intervention on worker knowledge, behavior and musculoskeletal risk.

    Science.gov (United States)

    Robertson, Michelle; Amick, Benjamin C; DeRango, Kelly; Rooney, Ted; Bazzani, Lianna; Harrist, Ron; Moore, Anne

    2009-01-01

    A large-scale field intervention study was undertaken to examine the effects of office ergonomics training coupled with a highly adjustable chair on office workers' knowledge and musculoskeletal risks. Office workers were assigned to one of three study groups: a group receiving the training and adjustable chair (n=96), a training-only group (n=63), and a control group (n=57). The office ergonomics training program was created using an instructional systems design model. A pre/post-training knowledge test was administered to all those who attended the training. Body postures and workstation set-ups were observed before and after the intervention. Perceived control over the physical work environment was higher for both intervention groups as compared to workers in the control group. A significant increase in overall ergonomic knowledge was observed for the intervention groups. Both intervention groups exhibited higher level behavioral translation and had lower musculoskeletal risk than the control group.

  12. Chaire en écosanté sur la santé des humains et des animaux dans ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Il y a aussi d'importantes lacunes en ce qui concerne les connaissances sur les effets à long terme possibles sur la santé des humains et des animaux, la pérennité des écosystèmes ainsi que les coûts et avantages des stratégies potentielles d'atténuation des risques. Par l'intermédiaire de la chaire en écosanté, ce projet ...

  13. Does an emotion-focused two-chair dialogue add to the therapeutic effect of the empathic attunement to affect?

    Science.gov (United States)

    Stiegler, Jan Reidar; Molde, Helge; Schanche, Elisabeth

    2017-09-27

    An increasing amount of research suggests that it is beneficial to work explicitly with emotions in psychotherapy. Emotion-focused therapy (EFT) utilizes interventions that are thought to enhance the evocativeness of emotional processing and facilitate explorations of new meaning. The purpose of this study was to examine the effect of such an intervention on therapeutic outcome. The intervention, a two-chair dialogue drawn from emotion-focused therapy, was added to the treatment conditions that consisted of empathically following the clients' emotional processes. The treatment comprised 2 phases. Using a multiple baseline design, 21 self-critical clients (15 women and 6 men) with clinically significant symptoms of depression and/or anxiety first received 5, 7, or 9 sessions of a baseline treatment focused on alliance building, empathic attunement to affect, and therapeutic presence and genuineness. A two-chair dialogue intervention was then added for 5 sessions. The symptoms were measured before each session using Beck's Depression Inventory, Beck's Anxiety Index, and Forms of Self-Criticizing/Attacking and Self-Reassuring Scale. An analysis using Hierarchical Linear Modelling revealed that the phase with the two-chair dialogue had a larger impact on symptoms of anxiety and depression when compared to the baseline phase. On BDI-II, there was a greater impact on somatic-affective components than cognitive components. Self-criticism was reduced when we used time as a predictor for both phases but not significantly more after introducing the intervention. The results corroborate that the two-chair dialogue intervention is associated with change beyond what is shown when relationship conditions alone are being provided. Implications and limitations are discussed. Copyright © 2017 John Wiley & Sons, Ltd.

  14. Autonomous Control of Eye Based Electric Wheel Chair with Obstacle Avoidance and Shortest Path Findings Based on Dijkstra Algorithm

    OpenAIRE

    Kohei Arai; Ronny Mardiyanto

    2011-01-01

    Autonomous Eye Based Electric Wheel Chair: EBEWC control system which allows handicap person (user) to control their EWC with their eyes only is proposed. Using EBEWC, user can move to anywhere they want on a same floor in a hospital autonomously with obstacle avoidance with visible camera and ultrasonic sensor. User also can control EBEWC by their eyes. The most appropriate route has to be determined with avoiding obstacles and then autonomous real time control has to be done. Such these pro...

  15. How often should sitting and rising from a chair be evaluated in patients with Duchenne muscular dystrophy?

    Directory of Open Access Journals (Sweden)

    Michele Emy Hukuda

    Full Text Available ABSTRACT Objective To determine how often sitting/rising from a chair should be assessed in Duchenne muscular dystrophy (DMD patients to avoid redundant/missing data. Methods Sitting/rising from a chair was evaluated in 26 DMD children (5-12 yrs, in three-month intervals, over twelve months, with the Functional Evaluation Scale (domain sitting/rising from a chair. Scores were compared by effect sizes (ES and standardized response means (SRM (responsiveness analysis. Results Sit-to-stand showed low-to-moderate responsiveness in three-month intervals (ES:0.23-0.32; SRM:0.36-0.68, moderate-to-high responsiveness in six-month intervals (ES:0.52-0.65; SRM:0.76-1.28, high responsiveness at nine-month (ES:0.84-0.91; SRM:1.26-1.64 and twelve-month intervals (ES:1.27; SRM:1.48. Stand-to-sit showed low responsiveness in three-month intervals (ES:0.26-0.49; SRM:0.37-0.42, moderate responsiveness in six-month intervals (ES:0.50-0.78; SRM:0.56-0.71, high responsiveness in nine-month (ES:0.94-1.00; SRM:0.84-1.02 and twelve-month intervals (ES:1.13; SRM:1.52. Conclusion Six months or longer intervals for reassessment are indicated to evaluate sitting/standing from a chair in DMD patients.

  16. Putting patients first. A conversation with Benjamin Chu, M.D., the new chair-elect of the AHA.

    Science.gov (United States)

    Weinstock, Matthew

    2011-11-01

    The son of immigrants, Benjamin Chu, M.D., has followed an unusual life path from New York's Chinatown to Southern California, where he is now an executive with Kaiser Foundation Hospitals and Health Plan. Dismayed by the daunting challenges facing health care, the AHA chair-elect became a strong believer that the system can and must change, always keeping the focus firmly on the patient.

  17. Rainfall declines over Queensland from 1951-2007 and links to the Subtropical Ridge and the SAM

    Energy Technology Data Exchange (ETDEWEB)

    Cottrill, D A [Bureau of Meteorology, 700 Collins St, Docklands, Melbourne, Victoria (Australia); Ribbe, J, E-mail: a.cottrill@bom.gov.a [University of Southern Queensland, Toowoomba, Queensland (Australia)

    2010-08-15

    Much of southern and eastern Australia including Queensland have experienced rainfall declines over recent decades affecting agricultural production and accelerating water infrastructure development. Rainfall declines from southern Australia have now been directly related to changes in the Southern Annular Mode (SAM) and the subtropical ridge. In southern and coastal Queensland, the rainfall declines have occurred mostly in the austral summer and autumn. Observations from this region reveal the rainfall decline is correlated to an increase in the mean sea level pressure (MSLP) at many stations. The largest increases in MSLP are over southeast Queensland and coastal regions, where some of the largest rainfall declines occur. This study indicates the subtropical ridge as one of the main factors in the rainfall decline over this region. SAM is also likely to be important, although its seasonal influence, apart from winter, is harder to determine.

  18. An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene

    Energy Technology Data Exchange (ETDEWEB)

    Tempel, W.; Wu, H.; Dombrovsky, L.; Zeng, H.; Loppnau, P.; Zhu, H.; Plotnikov, A.N.; Bochkarev, A.; (Toronto)

    2010-08-17

    A recent survey of protein expression patterns in patients with Alzheimer's disease (AD) has identified ece2 (chromosome: 3; Locations: 3q27.1) as the most significantly downregulated gene within the tested group. ece2 encodes endothelin-converting enzyme ECE2, a metalloprotease with a role in neuropeptide processing. Deficiency in the highly homologous ECE1 has earlier been linked to increased levels of AD-related {beta}-amyloid peptide in mice, consistent with a role for ECE in the degradation of that peptide. Initially, ECE2 was presumed to resemble ECE1, in that it comprises a single transmembrane region of {approx}20 residues flanked by a small amino-terminal cytosolic segment and a carboxy-terminal lumenar peptidase domain. The carboxy-terminal domain has significant sequence similarity to both neutral endopeptidase, for which an X-ray structure has been determined, and Kell blood group protein. After their initial discovery, multiple isoforms of ECE1 and ECE2 were discovered, generated by alternative splicing of multiple exons. The originally described ece2 transcript, RefSeq NM{_}174046, contains the amino-terminal cytosolic portion followed by the transmembrane region and peptidase domain (Fig. 1, isoform B). Another ece2 transcript, available from the Mammalian Gene Collection under MGC2408 (Fig. 1, isoform C), RefSeq accession NM{_}032331, is predicted to be translated into a 255 residue peptide with low but detectable sequence similarity to known S-adenosyl-L-methionine (SAM)-dependent methyltransferases (SAM-MTs), such as the hypothetical protein TT1324 from Thermus thermophilis, PDB code 2GS9, which shares 30% amino acid sequence identity with ECE2 over 138 residues of the sequence. Intriguingly, another 'elongated' ece2 transcript (Fig. 1, isoform A) (RefSeq NM{_}014693) contains an amino-terminal portion of the putative SAM-MT domain, the transmembrane domain, and the protease domain. This suggests the possibility for coexistence of

  19. Benchmark Simulations of the Thermal-Hydraulic Responses during EBR-II Inherent Safety Tests using SAM

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Rui; Sumner, Tyler S.

    2016-04-17

    An advanced system analysis tool SAM is being developed for fast-running, improved-fidelity, and whole-plant transient analyses at Argonne National Laboratory under DOE-NE’s Nuclear Energy Advanced Modeling and Simulation (NEAMS) program. As an important part of code development, companion validation activities are being conducted to ensure the performance and validity of the SAM code. This paper presents the benchmark simulations of two EBR-II tests, SHRT-45R and BOP-302R, whose data are available through the support of DOE-NE’s Advanced Reactor Technology (ART) program. The code predictions of major primary coolant system parameter are compared with the test results. Additionally, the SAS4A/SASSYS-1 code simulation results are also included for a code-to-code comparison.

  20. Sulphur-bearing Compounds Detected by MSL SAM Evolved Gas Analysis of Materials from Yellowknife Bay, Gale Crater, Mars

    Science.gov (United States)

    McAdam, A. C.; Franz, H. B.; Archer, P. D. Jr.; Sutter, B.; Eigenbrode, J. L.; Freissinet, C.; Atreya, S. K.; Bish, D. L.; Blake, D. F.; Brunner, A.; hide

    2014-01-01

    The Sample Analysis at Mars (SAM) and Chemistry and Mineralogy (CheMin) instruments on the Mars Science Laboratory (MSL) analysed several subsamples of sample fines (<150 µm) from three sites in Yellowknife Bay, an aeolian bedform termed Rocknest (hereafter "RN") and two samples drilled from the Sheepbed mudstone at sites named John Klein ("JK") and Cumberland ("CB"). SAM's evolved gas analysis (EGA) mass spectrometry detected H2O, CO2, O2, H2, SO2, H2S, HCl, NO, OCS, CS2 and other trace gases. The identity of evolved gases and temperature (T) of evolution can support mineral detection by CheMin and place constraints on trace volatile-bearing phases present below the CheMin detection limit or difficult to characterize with XRD (e.g., X-ray amorphous phases). Here, we focus on potential constraints on phases that evolved SO2, H2S, OCS, and CS2 during thermal analysis.