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Sample records for vi beta turn

  1. An Active Insect Kinin Analog with 4-Aminopyroglutamate, A Novel cis-Peptide Bond, Type VI beta-Turn Motif

    Science.gov (United States)

    2004-01-01

    Kinin Analogs in the Cricket Acheta domesticus Peptidomimetic Analog Stimulation of Malpighian Tubule Fluid Secretion-EC50 (10 7M) (% maximal...Malpighian tubule fluid secretion in the cricket, Acheta domesticus . Active Insect Kinin Analog with Type VI Turn-Mimic 4-Aminopyroglutamate 415 zole moiety

  2. Type VI collagen increases cell survival and prevents anti-beta 1 integrin-mediated apoptosis.

    Science.gov (United States)

    Howell, S J; Doane, K J

    1998-05-25

    Cell-matrix interactions are important in the development of the avian cornea. Type VI collagen is present within the periocular mesenchyme prior to the migration of cells into the corneal stroma and is abundant in the mature stroma. Whether the interaction of cells with type VI collagen is essential for cellular survival in the cornea is not known. In the present study, we examined the interaction of corneal cells with type VI collagen in vitro to determine if it can increase cell proliferation and decrease apoptosis. In vivo analysis demonstrated that apoptosis occurs in the periocular region during early stages of avian corneal development, but in fully mature corneas apoptosis only occurs in the corneal epithelium and not in the stroma. In vitro analysis examined the importance of beta 1 integrin interactions with type VI collagen in mature corneal fibroblasts and the precursor cells. Using an anti-beta 1 integrin blocking antibody, CSAT, integrin/matrix interactions were disrupted. Results indicated that viability of both corneal fibroblasts and periocular mesenchyme cells was greater on type VI collagen than on type I collagen or BSA-blocked glass. In addition, less apoptosis was observed for both cell types on type VI collagen when beta 1 integrin--matrix interactions were disrupted. These data indicated that these cells require intact beta 1 interactions with type I collagen and with BSA-coated glass controls to remain viable. Thus, type VI collagen may play a role in the rescue of corneal cells from anti-beta 1 integrin-induced apoptosis by increasing cell survival, probably via a non-beta 1 integrin-dependent mechanism.

  3. Galpha(q) and phospholipase C-beta: turn on, turn off, and do it fast.

    Science.gov (United States)

    Ross, Elliott M

    2011-02-08

    Heterotrimeric G proteins and G protein-coupled receptors represent conserved protein families with origins in the prokaryotes, but the various G protein-regulated effectors are heterogeneous in structure and function. The effectors apparently evolved ways to listen to G proteins late in their evolutionary histories. The structure of a complex between the effector protein phospholipase C-β3 (PLC-β3) and its activator, Gα(q), suggests that several effectors independently evolved a structurally similar helix-turn-helix segment for G protein recognition. PLC-βs are also guanosine triphosphatase (GTPase)-activating proteins (GAPs) for the G(q) that activates them. In a second example of convergent evolution, the GAP activity of these proteins depends on a flexible asparagine-containing loop that resembles the GAP site on RGS proteins, another family of G protein GAPs. Together, these two sites are proposed to cooperate to enable fast binding to activated Gα(q), followed by fast deactivation. This cycle allows rapid sampling of the activation state of G(q)-coupled receptors while providing efficient signal transduction.

  4. A combinatorial method for solution-phase synthesis of labeled bivalent beta-turn mimics.

    Science.gov (United States)

    Angell, Yu; Chen, Dianjun; Brahimi, Fouad; Saragovi, H Uri; Burgess, Kevin

    2008-01-16

    Piperidine-functionalized, 1,4-disubstituted-1,2,3-triazoles of generic structure 1 were conceived as "minimalist" mimics of peptidic beta-turn structures. Key features of these molecules include (i) the possibility of incorporating amino acid side chains corresponding to many of the protein amino acids; (ii) a close correspondence of separations of these side chains to i + 1 to i + 2 residues in turns; (iii) facile adjustment of the side-chain vectors on docking while only influencing two critical degrees of freedom; and (iv) some electrostatic polarity. Fifteen monomers of this type were made via copper-mediated cycloaddition reactions. Solution-phase methodologies were devised to assemble these monomers into bivalent compounds in high purity states (typically >85%) so that they could be used in first-pass biological assays without further purification. The skeleton for forming these bivalent compounds is triazine-based. There is a third site which allowed for introduction of a fluorescent label (library of compounds 2) or an alkyne-functionalized triethylene glycol chain (library of compounds 3) included to promote water-solubility and to allow incorporation of probes via copper-mediated cycloaddition reactions. In the event, two 135-membered libraries were prepared, one consisting of compounds 2 and the other of 3. No protecting groups or coupling agents were required; these attributes of the method were important to allow most of the products to be obtained in over 85% purities. The fluorescein-tagged library of compounds 2 was screened in a fluorescence-activated cell sorting (FACS) assay using cells transfected to overexpress one of the following neurotrophin receptors: TrkA, TrkC, and p75. Preliminary findings indicate four compounds 2gm, 2gn, 2gi, and 2gj bound the TrkA receptor selectively; all of these contain a threonine-lysine turn mimic. Thus, a pharmacological probe for the TrkA receptor has been developed.

  5. The crystal structure of beta-alanine synthase from Drosophila melanogaster reveals a homooctameric helical turn-like assembly.

    Science.gov (United States)

    Lundgren, Stina; Lohkamp, Bernhard; Andersen, Birgit; Piskur, Jure; Dobritzsch, Doreen

    2008-04-11

    Beta-alanine synthase (betaAS) is the third enzyme in the reductive pyrimidine catabolic pathway, which is responsible for the breakdown of the nucleotide bases uracil and thymine in higher organisms. It catalyzes the hydrolysis of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyrate to the corresponding beta-amino acids. betaASs are grouped into two phylogenetically unrelated subfamilies, a general eukaryote one and a fungal one. To reveal the molecular architecture and understand the catalytic mechanism of the general eukaryote betaAS subfamily, we determined the crystal structure of Drosophila melanogaster betaAS to 2.8 A resolution. It shows a homooctameric assembly of the enzyme in the shape of a left-handed helical turn, in which tightly packed dimeric units are related by 2-fold symmetry. Such an assembly would allow formation of higher oligomers by attachment of additional dimers on both ends. The subunit has a nitrilase-like fold and consists of a central beta-sandwich with a layer of alpha-helices packed against both sides. However, the core fold of the nitrilase superfamily enzymes is extended in D. melanogaster betaAS by addition of several secondary structure elements at the N-terminus. The active site can be accessed from the solvent by a narrow channel and contains the triad of catalytic residues (Cys, Glu, and Lys) conserved in nitrilase-like enzymes.

  6. The effect of beta-turn structure on the permeation of peptides across monolayers of bovine brain microvessel endothelial cells

    DEFF Research Database (Denmark)

    Sorensen, M; Steenberg, B; Knipp, G T

    1997-01-01

    PURPOSE: To investigate the effects of the beta-turn structure of a peptide on its permeation via the paracellular and transcellular routes across cultured bovine brain microvessel endothelial cell (BBMEC) monolayers, an in vitro model of the blood-brain barrier (BBB). METHODS: The effective...

  7. Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo

    DEFF Research Database (Denmark)

    Kuijpers, Marijke J E; Schulte, Valerie; Bergmeier, Wolfgang

    2003-01-01

    in the formation of vaso-occlusive thrombi. We previously demonstrated that the immunoglobulin receptor glycoprotein VI (GPVI), but not integrin alpha2beta1, is essential in priming platelet-collagen interaction and subsequent aggregation. Here, we report that these receptors have yet a complementary function...

  8. NetTurnP – Neural Network Prediction of Beta-turns by Use of Evolutionary Information and Predicted Protein Sequence Features

    DEFF Research Database (Denmark)

    Petersen, Bent; Lundegaard, Claus; Petersen, Thomas Nordahl

    2010-01-01

    is the highest reported performance on a two-class prediction of β-turn and not-β-turn. Furthermore NetTurnP shows improved performance on some of the specific β-turn types. In the present work, neural network methods have been trained to predict β-turn or not and individual β-turn types from the primary amino......β-turns are the most common type of non-repetitive structures, and constitute on average 25% of the amino acids in proteins. The formation of β-turns plays an important role in protein folding, protein stability and molecular recognition processes. In this work we present the neural network method...... NetTurnP, for prediction of two-class β-turns and prediction of the individual β-turn types, by use of evolutionary information and predicted protein sequence features. It has been evaluated against a commonly used dataset BT426, and achieves a Matthews correlation coefficient of 0.50, which...

  9. NetTurnP--neural network prediction of beta-turns by use of evolutionary information and predicted protein sequence features.

    Directory of Open Access Journals (Sweden)

    Bent Petersen

    Full Text Available UNLABELLED: β-turns are the most common type of non-repetitive structures, and constitute on average 25% of the amino acids in proteins. The formation of β-turns plays an important role in protein folding, protein stability and molecular recognition processes. In this work we present the neural network method NetTurnP, for prediction of two-class β-turns and prediction of the individual β-turn types, by use of evolutionary information and predicted protein sequence features. It has been evaluated against a commonly used dataset BT426, and achieves a Matthews correlation coefficient of 0.50, which is the highest reported performance on a two-class prediction of β-turn and not-β-turn. Furthermore NetTurnP shows improved performance on some of the specific β-turn types. In the present work, neural network methods have been trained to predict β-turn or not and individual β-turn types from the primary amino acid sequence. The individual β-turn types I, I', II, II', VIII, VIa1, VIa2, VIba and IV have been predicted based on classifications by PROMOTIF, and the two-class prediction of β-turn or not is a superset comprised of all β-turn types. The performance is evaluated using a golden set of non-homologous sequences known as BT426. Our two-class prediction method achieves a performance of: MCC=0.50, Qtotal=82.1%, sensitivity=75.6%, PPV=68.8% and AUC=0.864. We have compared our performance to eleven other prediction methods that obtain Matthews correlation coefficients in the range of 0.17-0.47. For the type specific β-turn predictions, only type I and II can be predicted with reasonable Matthews correlation coefficients, where we obtain performance values of 0.36 and 0.31, respectively. CONCLUSION: The NetTurnP method has been implemented as a webserver, which is freely available at http://www.cbs.dtu.dk/services/NetTurnP/. NetTurnP is the only available webserver that allows submission of multiple sequences.

  10. Prediction of beta-turns at over 80% accuracy based on an ensemble of predicted secondary structures and multiple alignments

    Directory of Open Access Journals (Sweden)

    Kurgan Lukasz

    2008-10-01

    Full Text Available Abstract Background β-turn is a secondary protein structure type that plays significant role in protein folding, stability, and molecular recognition. To date, several methods for prediction of β-turns from protein sequences were developed, but they are characterized by relatively poor prediction quality. The novelty of the proposed sequence-based β-turn predictor stems from the usage of a window based information extracted from four predicted three-state secondary structures, which together with a selected set of position specific scoring matrix (PSSM values serve as an input to the support vector machine (SVM predictor. Results We show that (1 all four predicted secondary structures are useful; (2 the most useful information extracted from the predicted secondary structure includes the structure of the predicted residue, secondary structure content in a window around the predicted residue, and features that indicate whether the predicted residue is inside a secondary structure segment; (3 the PSSM values of Asn, Asp, Gly, Ile, Leu, Met, Pro, and Val were among the top ranked features, which corroborates with recent studies. The Asn, Asp, Gly, and Pro indicate potential β-turns, while the remaining four amino acids are useful to predict non-β-turns. Empirical evaluation using three nonredundant datasets shows favorable Qtotal, Qpredicted and MCC values when compared with over a dozen of modern competing methods. Our method is the first to break the 80% Qtotal barrier and achieves Qtotal = 80.9%, MCC = 0.47, and Qpredicted higher by over 6% when compared with the second best method. We use feature selection to reduce the dimensionality of the feature vector used as the input for the proposed prediction method. The applied feature set is smaller by 86, 62 and 37% when compared with the second and two third-best (with respect to MCC competing methods, respectively. Conclusion Experiments show that the proposed method constitutes an

  11. A new turn-on fluorimetric method for the rapid speciation of Cr(III)/Cr(VI) species in tea samples with rhodamine-based fluorescent reagent

    Science.gov (United States)

    Özyol, Esra; Saçmacı, Şerife; Saçmacı, Mustafa; Ülgen, Ahmet

    2018-02-01

    A new fluorimetric method with rhodamine-based fluorescent agent was developed for the rapid speciation of Cr(III)/Cr(VI) in tea, soil and water samples. The system, which utilizes a fluorescent reagent, was used for the first time after synthesis/characterization of 3‧,6‧-bis(diethylamino)-2-{[(1E)-(2,4-dimethoxyphenyl)methylene] amino}spiro[isoindole-1,9‧-xanthen]-3(2H)-one (BDAS). The reagent responds instantaneously at room temperature in a 1:1 stoichiometric manner to the amount of Cr(III). The selectivity of this system for Cr(III) over other metal ions is remarkably high, and its sensitivity is below 0.01 mg L- 1 in aqueous solutions which enables a simplification without any pretreatment of the real sample. The method has a wide linear range of 0.1-10 mg L- 1 and a detection limit of 0.15 μg L- 1 for Cr(III) while the relative standard deviation was 0.1% for 0.1 mg L- 1 Cr(III) concentration. The results of detection and recovery experiments for Cr(III) in tea, soil and water were satisfactory, indicating that the method has better feasibility and application potential in the routine determination and speciation of Cr(III)/Cr(VI). The results of analysis of the certified reference material (INCT-TL-1 tea sample and CWW-TM-D waste water) are in good agreement with the certified value.

  12. Six amino acid changes confined to the leucine-rich repeat beta-strand/beta-turn motif determine the difference between the P and P2 rust resistance specificities in flax.

    Science.gov (United States)

    Dodds, P N; Lawrence, G J; Ellis, J G

    2001-01-01

    At least six rust resistance specificities (P and P1 to P5) map to the complex P locus in flax. The P2 resistance gene was identified by transposon tagging and transgenic expression. P2 is a member of a small multigene family and encodes a protein with nucleotide binding site (NBS) and leucine-rich repeat (LRR) domains and an N-terminal Toll/interleukin-1 receptor (TIR) homology domain, as well as a C-terminal non-LRR (CNL) domain of approximately 150 amino acids. A related CNL domain was detected in almost half of the predicted Arabidopsis TIR-NBS-LRR sequences, including the RPS4 and RPP1 resistance proteins, and in the tobacco N protein, but not in the flax L and M proteins. Presence or absence of this domain defines two subclasses of TIR-NBS-LRR resistance genes. Truncations of the P2 CNL domain cause loss of function, and evidence for diversifying selection was detected in this domain, suggesting a possible role in specificity determination. A spontaneous rust-susceptible mutant of P2 contained a G-->E amino acid substitution in the GLPL motif, which is conserved in the NBS domains of plant resistance proteins and the animal cell death control proteins APAF-1 and CED4, providing direct evidence for the importance of this motif in resistance gene function. A P2 homologous gene isolated from a flax line expressing the P resistance specificity encodes a protein with only 10 amino acid differences from the P2 protein. Chimeric gene constructs indicate that just six of these amino acid changes, all located within the predicted beta-strand/beta-turn motif of four LRR units, are sufficient to alter P2 to the P specificity.

  13. Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha

    DEFF Research Database (Denmark)

    Bergmeier, W; Bouvard, D; Eble, J A

    2001-01-01

    the venom of Calloselasma rhodostoma, induces platelet activation that can be blocked by monoclonal antibodies against alpha(2)beta(1) integrin. This finding suggested that clustering of alpha(2)beta(1) integrin by rhodocytin is sufficient to induce platelet activation and led to the hypothesis...... lacking both alpha(2)beta(1) integrin and the activating collagen receptor GPVI responded normally to rhodocytin. Finally, even after additional proteolytic removal of the 45-kDa N-terminal domain of GPIbalpha rhodocytin induced aggregation of these platelets. These results demonstrate that rhodocytin...

  14. Folding control in cyclic peptides through N-methylation pattern selection: formation of antiparallel beta-sheet dimers, double reverse turns and supramolecular helices by 3alpha,gamma cyclic peptides.

    Science.gov (United States)

    Amorín, Manuel; Castedo, Luis; Granja, Juan R

    2008-01-01

    Peptide foldamers constitute a growing class of nanomaterials with potential applications in a wide variety of chemical, medical and technological fields. Here we describe the preparation and structural characteristics of a new class of cyclic peptide foldamers (3alpha,gamma-CPs) that, depending on their backbone N-methylation patterns and the medium, can either remain as flat rings that dimerize through arrays of hydrogen bonds of antiparallel beta-sheet type, or can fold into twisted double reverse turns that, in the case of double gamma-turns, associate in nonpolar solvents to form helical supramolecular structures. A 3alpha,gamma-CP consists of a number of multiples of a repeat unit made up of four amino acid residues of alternating chirality: three corresponding to alpha-amino acids and one to a gamma-amino acid (a cis-3-aminocycloalkanecarboxylic acid).

  15. Geometry VI

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 8. Geometry VI - Space-the Final Frontier. Kapil H Paranjape. Series Article Volume 1 Issue 8 August 1996 pp 28-33. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/08/0028-0033 ...

  16. VI KA’

    DEFF Research Database (Denmark)

    Sprogøe, Jonas

    2012-01-01

    Artiklen handler om hvordan man kan bruge et spil til at udvikle og måle kompetencer. Artiklen diskuterer forskellige forståelser kompetencebegrebet og diskuterer hvordan Vi Ka'-spillet bidrager til at indfange den mere aktive forståelse af kompetence, som noget du gør i en bestemt kontekst....

  17. Taking Turns

    Science.gov (United States)

    Hopkins, Brian

    2010-01-01

    Two people take turns selecting from an even number of items. Their relative preferences over the items can be described as a permutation, then tools from algebraic combinatorics can be used to answer various questions. We describe each person's optimal selection strategies including how each could make use of knowing the other's preferences. We…

  18. Mucopolysaccharidosis VI

    Science.gov (United States)

    2010-01-01

    Mucopolysaccharidosis VI (MPS VI) is a lysosomal storage disease with progressive multisystem involvement, associated with a deficiency of arylsulfatase B leading to the accumulation of dermatan sulfate. Birth prevalence is between 1 in 43,261 and 1 in 1,505,160 live births. The disorder shows a wide spectrum of symptoms from slowly to rapidly progressing forms. The characteristic skeletal dysplasia includes short stature, dysostosis multiplex and degenerative joint disease. Rapidly progressing forms may have onset from birth, elevated urinary glycosaminoglycans (generally >100 μg/mg creatinine), severe dysostosis multiplex, short stature, and death before the 2nd or 3rd decades. A more slowly progressing form has been described as having later onset, mildly elevated glycosaminoglycans (generally sialidosis and mucolipidosis. Before enzyme replacement therapy (ERT) with galsulfase (Naglazyme®), clinical management was limited to supportive care and hematopoietic stem cell transplantation. Galsulfase is now widely available and is a specific therapy providing improved endurance with an acceptable safety profile. Prognosis is variable depending on the age of onset, rate of disease progression, age at initiation of ERT and on the quality of the medical care provided. PMID:20385007

  19. Mucopolysaccharidosis VI

    Directory of Open Access Journals (Sweden)

    Harmatz Paul

    2010-04-01

    Full Text Available Abstract Mucopolysaccharidosis VI (MPS VI is a lysosomal storage disease with progressive multisystem involvement, associated with a deficiency of arylsulfatase B leading to the accumulation of dermatan sulfate. Birth prevalence is between 1 in 43,261 and 1 in 1,505,160 live births. The disorder shows a wide spectrum of symptoms from slowly to rapidly progressing forms. The characteristic skeletal dysplasia includes short stature, dysostosis multiplex and degenerative joint disease. Rapidly progressing forms may have onset from birth, elevated urinary glycosaminoglycans (generally >100 μg/mg creatinine, severe dysostosis multiplex, short stature, and death before the 2nd or 3rd decades. A more slowly progressing form has been described as having later onset, mildly elevated glycosaminoglycans (generally ARSB gene, located in chromosome 5 (5q13-5q14. Over 130 ARSB mutations have been reported, causing absent or reduced arylsulfatase B (N-acetylgalactosamine 4-sulfatase activity and interrupted dermatan sulfate and chondroitin sulfate degradation. Diagnosis generally requires evidence of clinical phenotype, arylsulfatase B enzyme activity ®, clinical management was limited to supportive care and hematopoietic stem cell transplantation. Galsulfase is now widely available and is a specific therapy providing improved endurance with an acceptable safety profile. Prognosis is variable depending on the age of onset, rate of disease progression, age at initiation of ERT and on the quality of the medical care provided.

  20. Turned on/turned off

    DEFF Research Database (Denmark)

    Petersen, Eva Bendix

    2016-01-01

    position, it attempts to sense into the lived experience of being subject to, and of, turns in social theory. As a whole the paper seeks to work with and allow for multiplicity in tone, focus, researcher positioning, reader positioning, and more, to see what knowledge that does not seek confident closure...

  1. Tight Turns

    Directory of Open Access Journals (Sweden)

    Jenifer Sutherland

    2013-01-01

    Full Text Available The plain text was task-oriented in a roundabout way, providing detailed instructions for how NOT to build an elaborate sequence of bridges, each one bound to produce, according to chapters one through twenty-three, disastrous results. Graphic novels disguised as illuminated letters twisted the tent-dwelling decipherer into painful self-recognition. The flashlight followed the phases of the moon. Meanwhile one strand of marginalia, written in anxious back-slant, pleaded for some kind of adjustable form for managing the confluence, especially during flood season. I like what we came up with. 'We' is a little big word. In fact the tent turns out to be one of those Borgesian core-tech structures allowing for astonishing internal expansion. There's not much we didn't get in there and not much in there that didn't get us. So I suppose that's it. This tent. This confluence. These children who found me here, turned text into life and made life home.

  2. Fermilab turns 50! Congratulations!

    CERN Multimedia

    Staff Association

    2017-01-01

    This year Fermilab turns 50 and the celebrations are ongoing. The ties between CERN and Fermilab are numerous and have been ranging from competition between two labs at the forefront of their field, e.g. with the chase of the top quark, finally discovered by Fermilab, to outright collaboration, e.g. on LHC low-beta quadrupole magnet development and production and in the CMS collaboration. In June, in the name of the CERN staff and scientific community, the CERN Staff Association sent a message to the Fermilab staff and scientific community, through Dr. Nigel Lockyer, Fermilab Director. The letter, and the assurance from Nigel Lockyer that the message has been passed onto the Fermilab community can be found on our website. Congratulations to Fermilab on its fiftieth Anniversary, and to the staff and collaborators who made this laboratory through their hard work, dedication and vision!

  3. Cranial mononeuropathy VI

    Science.gov (United States)

    ... Abducens palsy; Lateral rectus palsy; VIth nerve palsy; Cranial nerve VI palsy; Sixth nerve palsy; Neuropathy - sixth nerve ... Cranial mononeuropathy VI is damage to the sixth cranial nerve. This nerve is also called the abducens nerve. ...

  4. Kandinsky's "Composition VI": Heideggerian Poetry in Noah's Ark

    Science.gov (United States)

    Hall, Joshua M.

    2012-01-01

    The author will begin his investigation of Wassily Kandinsky's painting "Composition VI" with Kandinsky's own commentary on the painting. He will then turn to the analysis of Kandinsky and the "Compositions" in John Sallis's book "Shades." Using this analysis as his point of departure, the author will consider how "Composition VI" resonates with…

  5. BIOSORPTION OF CHROMIUM (VI) USING IMMOBILIZED ...

    African Journals Online (AJOL)

    USER

    2016-05-20

    May 20, 2016 ... water and air. It affects the growth of flora and fauna which in turn affect human health negatively. Chromium could also bio-accumulate in plants and animals and this becomes ... The sorption kinetic models of Cr (VI) onto the biosorbents were examined with ... bulk density, moisture and ash contents.

  6. Vi, de civiliserede

    DEFF Research Database (Denmark)

    Nyemann, Dorthe

    2016-01-01

    Vi har i årtier troet på, at mennesker under de rette omstændigheder kan lykkes med at leve i fred og fordragelighed med hinanden. Skal vi til at erkende, at også vores samfundsstrukturer kun er en tynd fernis ovenpå et utæmmeligt voldspotentiale og egoisme?......Vi har i årtier troet på, at mennesker under de rette omstændigheder kan lykkes med at leve i fred og fordragelighed med hinanden. Skal vi til at erkende, at også vores samfundsstrukturer kun er en tynd fernis ovenpå et utæmmeligt voldspotentiale og egoisme?...

  7. Beta Blockers

    Science.gov (United States)

    Beta blockers Beta blockers, also called beta-adrenergic blocking agents, treat a variety of conditions, such as high blood pressure and migraines. ... this class of medication. By Mayo Clinic Staff Beta blockers, also known as beta-adrenergic blocking agents, are ...

  8. The Digital Turn

    NARCIS (Netherlands)

    Westera, Wim

    2013-01-01

    Westera, W. (2013, 22 May). The Digital Turn. How the internet transforms our existence. Invited presentation at the symposium "Onderwijsvernieuwen in crisistijd", Heerlen, The Netherlands: Open Universiteit.

  9. Beta limits for torsatrons

    Science.gov (United States)

    Bauer, F.; Betancourt, O.; Garabedian, P.; Shohet, J. L.

    1981-01-01

    An ideal magnetohydrodynamic equilibrium and stability code is used to study ballooning modes in torsatrons. The most dangerous modes turn out to be those with low poloidal and toroidal wave numbers. Beta limits for equilibrium and stability are determined for an [unk] = 2 ultimate torsatron with large [unk] = 1 and [unk] = 3 sidebands. PMID:16592941

  10. and dioxouranium(vi)

    African Journals Online (AJOL)

    a

    Thorium(IV) and uranium(VI) with atomic radii of 1.65 and .... to ν(NH) vibrations. Practically no effect on these frequencies after complexation precludes the possibility of metal-coordination at this group. The absorptions at 1600 ... observation suggests involvement of unsaturated nitrogen atoms of the two azomethine groups.

  11. II-VI semiconductor compounds

    CERN Document Server

    1993-01-01

    For condensed matter physicists and electronic engineers, this volume deals with aspects of II-VI semiconductor compounds. Areas covered include devices and applications of II-VI compounds; Co-based II-IV semi-magnetic semiconductors; and electronic structure of strained II-VI superlattices.

  12. Review Essay: Turn, Turn, Turn Around—Till Categories Blur

    Directory of Open Access Journals (Sweden)

    Lars Allolio-Näcke

    2008-01-01

    Full Text Available I begin this review by introducing the book and discussing its manifest content chapter by chapter (see 2.1, focusing particularly on the author's argumentation concerning the development of new orientations in cultural studies and on how, in relation to the turns discussed, the names of the researchers and central categories involved are collected. In a second step, I give a close reading of the book's latent content, which I consider to be more important (see 2.2. In this context I discuss several questions of scientific politics—especially the issue of hegemonic claims. Thirdly, I read the book from the critical standpoint of a psychologist, a sociologist and a theologian and show the shortcomings of BACHMANN-MEDICK's outsider perspective on these disciplines. In this regard I read the book again and provide a critique of the quality of the author's scientific performance (see 3. Finally, I state the reasons I do not recommend reading this book (see 4. URN: urn:nbn:de:0114-fqs0801266

  13. Complexation of uranium(VI) with peptidoglycan.

    Science.gov (United States)

    Barkleit, Astrid; Moll, Henry; Bernhard, Gert

    2009-07-21

    We investigated the interaction of UO(2)(2+) with peptidoglycan (PG), the main part of the outer membrane of Gram-positive bacteria, by potentiometric titration and time-resolved laser-induced fluorescence spectroscopy (TRLFS) over a wide pH (2.0 to 9.0) and concentration range (10(-5) to 10(-4) M U(vi), 0.01 to 0.2 g L(-1) PG). With potentiometry two different dissociation constants for the carboxyl sites of glutamic acid and diaminopimelic acid (pK(a) = 4.55 +/- 0.02 and 6.31 +/- 0.01), and one averaged pK(a) for hydroxyl and amino groups (which are not distinguishable) (9.56 +/- 0.03) and the site densities could be identified. With potentiometry three different uranyl PG complexes were ascertained: two 1 : 1 uranyl carboxyl complexes R-COO-UO(2)(+), one with the glutamic acid carboxyl group (log beta(110) = 4.02 +/- 0.03), which has a very small formation ratio, and one with the diaminopimelic acid carboxyl group (log beta(110) = 7.28 +/- 0.03), and a mixed 1 : 1 : 1 complex with additional hydroxyl or amino coordination, R-COO-UO(2)((+))-A(i)-R (A(i) = NH(2) or O(-)) (log beta(1110) = 14.95 +/- 0.02). With TRLFS, also three, but different, species could be identified: a 1 : 1 uranyl carboxyl complex R-COO-UO(2)(+) (log beta(110) = 6.9 +/- 0.2), additionally a 1 : 2 uranyl carboxyl complex (R-COO)(2)-UO(2) (log beta(120) = 12.1 +/- 0.2), both with diaminopimelic acid carboxyl groups, and the mixed species R-COO-UO(2)((+))-A(i)-R (A(i) = NH(2) or O(-)) (log beta(1110) = 14.5 +/- 0.1). The results are in accordance within the errors of determination.

  14. VI Nukitsa konkurss

    Index Scriptorium Estoniae

    2002-01-01

    VI Nukitsa konkursi auhinnad: Kirjanikud: I - Henno Käo ("Kusagil mujal"); II - Aidi Vallik ("Kuidas elad, Ann?"); III - Artur Jurin ("Piletijaht: uued segadused Kilulibeda teel"). Kunstnikud: I - Karel Korp (Leelo Tungla ja Karel Korbi "Tema amet"); II - Edgar Valter ("Kuidas õppida vaatama?"); III - Artur Jurin - ("Piletijaht: uued segadused Kilulibeda teel"). Täiskasvanute küsitluse võitis nii teksti kui piltidega Ene-Maris Tali ja Tarmo Tali "Tähtraamat. Aastaring Maarjamaal"

  15. Hydrodynamics of Turning Flocks.

    Science.gov (United States)

    Yang, Xingbo; Marchetti, M Cristina

    2015-12-18

    We present a hydrodynamic model of flocking that generalizes the familiar Toner-Tu equations to incorporate turning inertia of well-polarized flocks. The continuum equations controlled by only two dimensionless parameters, orientational inertia and alignment strength, are derived by coarse-graining the inertial spin model recently proposed by Cavagna et al. The interplay between orientational inertia and bend elasticity of the flock yields anisotropic spin waves that mediate the propagation of turning information throughout the flock. The coupling between spin-current density to the local vorticity field through a nonlinear friction gives rise to a hydrodynamic mode with angular-dependent propagation speed at long wavelengths. This mode becomes unstable as a result of the growth of bend and splay deformations augmented by the spin wave, signaling the transition to complex spatiotemporal patterns of continuously turning and swirling flocks.

  16. Turning lead into gold

    DEFF Research Database (Denmark)

    Jensen, Steffen Moltrup Ernø

    For years the field of entrepreneurship has been blinded by the alchemical promise of turning lead into gold, of finding the ones most likely to become the next Branson, Zuckerberg or Gates. The promise has been created in the midst of political and scientific agendas where certain individuals...

  17. Turning Desirements into Requirements

    Science.gov (United States)

    2015-09-01

    carrier op- erations now leads to the two additional requirements to limit aircraft weight and limit aircraft size. A vivid example involves a missile...with worthy performance. None of these communications steps are easy. The abilities to innovate and to imagine often begin tortuous processes to turn

  18. Vi tror, vi forstår hinanden, men det gør vi ikke

    DEFF Research Database (Denmark)

    Boysen, Mikkel Snorre Wilms

    2016-01-01

    Vores verdensbillede er baseret på en tro på, at vi forstår hinanden. Men meget tyder på, at denne tro snarere er en illusion. Derfor må vi indstille os på, at der skal en særlig indsats til, hvis vi skal kunne forstå vores omverden og menneskene i den......Vores verdensbillede er baseret på en tro på, at vi forstår hinanden. Men meget tyder på, at denne tro snarere er en illusion. Derfor må vi indstille os på, at der skal en særlig indsats til, hvis vi skal kunne forstå vores omverden og menneskene i den...

  19. Optimizing turning for locomotion

    Science.gov (United States)

    Burton, Lisa; Hatton, Ross; Choset, Howie; Hosoi, A. E.

    2012-02-01

    Speed and efficiency are common and often adequate metrics to compare locomoting systems. These metrics, however, fail to account for a system's ability to turn, a key component in a system's ability to move a confined environment and an important factor in optimal motion planning. To explore turning strokes for a locomoting system, we develop a kinematic model to relate a system's shape configuration to its external velocity. We exploit this model to visualize the dynamics of the system and determine optimal strokes for multiple systems, including low Reynolds number swimmers and biological systems dominated by inertia. Understanding how shape configurations are related to external velocities enables a better understanding of biological and man made systems. Using these tools, we can justify biological system motion and determine optimal shape configurations for robots to maneuver through difficult environments.

  20. Diamond turning of glass

    Energy Technology Data Exchange (ETDEWEB)

    Blackley, W.S.; Scattergood, R.O.

    1988-12-01

    A new research initiative will be undertaken to investigate the critical cutting depth concepts for single point diamond turning of brittle, amorphous materials. Inorganic glasses and a brittle, thermoset polymer (organic glass) are the principal candidate materials. Interrupted cutting tests similar to those done in earlier research are Ge and Si crystals will be made to obtain critical depth values as a function of machining parameters. The results will provide systematic data with which to assess machining performance on glasses and amorphous materials

  1. Hungary's U-Turn

    OpenAIRE

    Kornai, János

    2015-01-01

    For two decades Hungary, like the other Eastern European countries, followed a general policy of establishing and strengthening the institutions of democracy, rule of law, and a market economy based on private property. However, since the elections of 2010, when Viktor Orbán's Fidesz party came to power, Hungary has made a dramatic U-turn. This article investigates the different spheres of society: political institutions, the rule of law, and the influence of state and market on one another, ...

  2. NEHRP turns 40

    Science.gov (United States)

    Leith, William S.

    2017-01-01

    This year, the National Earthquake Hazards Reduction Program (NEHRP) turns 40, four decades since the Earthquake Hazards Reduction Act of 1977 was enacted establishing the Program, spurring numerous federal, state, and community actions to reduce earthquake losses in the U.S.A. and its territories and setting a standard for earthquake loss‐reduction projects internationally. Four agencies are partners in NEHRP: the Federal Emergency Management Agency (FEMA), the National Institute of Standards and Technology (NIST, the lead agency), the National Science Foundation (NSF), and the U.S. Geological Survey (USGS).

  3. Cr(VI Adsorption on Red Mud Modified by Lanthanum: Performance, Kinetics and Mechanisms.

    Directory of Open Access Journals (Sweden)

    You-Wei Cui

    Full Text Available Water pollution caused by the highly toxic metal hexavalent chromium (Cr(VI creates significant human health and ecological risks. In this study, a novel adsorbent was used to treat Cr(VI-containing wastewater; the adsorbent was prepared using red mud (RM generated from the alumina production industry and the rare earth element lanthanum. This study explored adsorption performance, kinetics, and mechanisms. Results showed that the adsorption kinetics of the RM modified by lanthanum (La-RM, followed the pseudo-second-order model, with a rapid adsorption rate. Cr(VI adsorption was positively associated with the absorbent dose, pH, temperature, and initial Cr(VI concentration; coexisting anions had little impact. The maximum Cr(VI adsorption capacity was 17.35 mg/g. Cr(VI adsorption on La-RM was a mono-layer adsorption pattern, following the Langmuir isotherm model. Thermodynamic parameters showed the adsorption was spontaneous and endothermic. The adsorption of Cr(VI on La-RM occurred as a result of LaOCl formation on the RM surface, which in turn further reacted with Cr(VI in the wastewater. This study highlighted a method for converting industrial waste into a valuable material for wastewater treatment. The novel absorbent could be used as a potential adsorbent for treating Cr(VI-contaminating wastewater, due to its cost-effectiveness and high adsorption capability.

  4. Cr(VI) Adsorption on Red Mud Modified by Lanthanum: Performance, Kinetics and Mechanisms

    Science.gov (United States)

    Cui, You-Wei; Li, Jie; Du, Zhao-Fu; Peng, Yong-Zhen

    2016-01-01

    Water pollution caused by the highly toxic metal hexavalent chromium (Cr(VI)) creates significant human health and ecological risks. In this study, a novel adsorbent was used to treat Cr(VI)-containing wastewater; the adsorbent was prepared using red mud (RM) generated from the alumina production industry and the rare earth element lanthanum. This study explored adsorption performance, kinetics, and mechanisms. Results showed that the adsorption kinetics of the RM modified by lanthanum (La-RM), followed the pseudo-second-order model, with a rapid adsorption rate. Cr(VI) adsorption was positively associated with the absorbent dose, pH, temperature, and initial Cr(VI) concentration; coexisting anions had little impact. The maximum Cr(VI) adsorption capacity was 17.35 mg/g. Cr(VI) adsorption on La-RM was a mono-layer adsorption pattern, following the Langmuir isotherm model. Thermodynamic parameters showed the adsorption was spontaneous and endothermic. The adsorption of Cr(VI) on La-RM occurred as a result of LaOCl formation on the RM surface, which in turn further reacted with Cr(VI) in the wastewater. This study highlighted a method for converting industrial waste into a valuable material for wastewater treatment. The novel absorbent could be used as a potential adsorbent for treating Cr(VI)-contaminating wastewater, due to its cost-effectiveness and high adsorption capability. PMID:27658113

  5. The Affective Turn

    Directory of Open Access Journals (Sweden)

    Alí Lara

    2013-11-01

    Full Text Available In the last decade studies on affect and emotions have become relevant in the social sciences. This is not just a fad guideline, but instead a simultaneous reader of public life changes and subjective experience, from which it is also being transformed the knowledge production. Such a trend has been known as ‘The Affective Turn’ within the Anglophone Academy. Here we will translate it as ‘El Giro Afectivo’. This turn, so far, has not dabbled in the social science literature that is written in Spanish. This paper draws on a singular panorama of discussions about contemporary social studies of affect and emotion, and it’s vertebrate by some of its expressions in the contemporary academy.

  6. A Quasar Turns On

    Science.gov (United States)

    Kohler, Susanna

    2017-02-01

    The intermediate Palomar Transient Factory (iPTF) has discovered a quasar the brightly-shining, active nucleus of a galaxy abruptly turning on in what appears to be the fastest such transition ever seen in such an object.A Rapid TransitionQuasars are expected to show variations in brightness on timescales of hours to millions of years, but its not often that we get to study their major variability in real time! So far, weve discovered only a dozen changing-look quasars active galactic nuclei that exhibit major changes in their spectral class and brightness between observations. Roughly half of these were quasars that turned on and half were quasars that turned off, generally on timescales of maybe 5 or 10 years.The dramatic change in spectrum of iPTF 16bco between the archival SDSS data from 2004 (bottom) and the follow-up spectroscopy from Keck 2+DEIMOS in 2016 (top). [Adapted from Gezari et al. 2017]In June 2016, however, a team of scientists led by Suvi Gezari (University of Maryland) discovered iPTF 16bco, a nuclear transient that wasnt there the last time Palomar checked in 2012. A search through archival Sloan Digital Sky Survey and GALEX data in addition to some follow-up X-ray imaging and spectroscopic observations told the team what they needed to know: iPTF 16bco is a quasar that only just turned on within the 500 days preceding the iPTF observations.This source, in fact, is a 100-million-solar-mass black hole located at the center of a galaxy at a redshift of z= 0.237. In just over a year, the source changed classification from a galaxy with weak narrow-line emission to a quasar with characteristic strong, broad emission lines and a ten-fold increase in continuum brightness! What caused this sudden transition?Instabilities at Fault?iPTF 16bco and the other known changing-look quasars with disappearing (red circles) and appearing (blue circles) broad-line emission. [Adapted from Gezari et al. 2017]Gezari and collaborators used the large number of recent

  7. Lattice Calibration with Turn-By-Turn BPM Data

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xiaobiao; /SLAC; Sebek, James; /SLAC

    2012-07-02

    Turn-by-turn beam position monitor (BPM) data from multiple BPMs are fitted with a tracking code to calibrate magnet strengths in a manner similar to the well known LOCO code. Simulation shows that this turn-by-turn method can be a quick and efficient way for optics calibration. The method is applicable to both linacs and ring accelerators. Experimental results for a section of the SPEAR3 ring is also shown.

  8. ViFiLite Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ViFiLite is a wireless infrastructure that utilizes the advantages of a V-band technology in supporting data gathering for structural health monitoring as well as...

  9. Skal vi have flere krondyr?

    DEFF Research Database (Denmark)

    Pedersen, Jens Christian

    2008-01-01

    Vi kunne have væsentligt flere krondyr i den danske natur end vi har i øjeblikket. Den primære årsag er jagt. Det viser en ny undersøgelse fra Danmarks Miljøundersøgelser ved Aarhus Universitet. Bestanden af krondyr er ganske vist steget meget siden 1970, men der er både plads og føde til mange...

  10. Turn by Turn Measurements at the KEK-ATF

    CERN Document Server

    Renier, Y; Tomas, R; Wendt, M; Eddy, N; Kubo, K; Kuroda, S; Naito, T; Okugi, T; Terunuma, N; Urakawa, J

    2013-01-01

    The ATF damping ring has been upgraded with new read-out electronics for the beam position monitors (BPM), capable to acquire the beam orbits on a turn-by-turn basis, as well as in a high resolution averaging mode. The new BPM system allows to improve optic corrections and to achieve an even smaller vertical emittance (<2pm). Experimental results are presented based on turn-by-turn beam orbit measurements in the ring, for estimating the β functions and dispersion along the lattice. A fast method to measure spectral line amplitude in a few turns is also presented, including the evaluation of chromaticity.

  11. QTL list: beta-car6.1 [PGDBj Registered plant list, Marker list, QTL list, Plant DB link and Genome analysis methods[Archive

    Lifescience Database Archive (English)

    Full Text Available QT95726 Cucumis melo Cucurbitaceae beta-car6.1 Beta-car quantity of Beta-carotene ...in mature fruit, Csf-2 gene (Beta-car4.1) ... LG_VI ... 66.7 4.71 ... 10.1007/s00122-008-0868-2 18773190

  12. QTL list: beta-car6.2 [PGDBj Registered plant list, Marker list, QTL list, Plant DB link and Genome analysis methods[Archive

    Lifescience Database Archive (English)

    Full Text Available QT95727 Cucumis melo Cucurbitaceae beta-car6.2 Beta-car quantity of Beta-carotene ...in mature fruit, Csf-2 gene (Beta-car4.1) ... LG_VI ... 142.5 4.62 ... 10.1007/s00122-008-0868-2 18773190

  13. Oxidation of Sulfonamides in Aqueous Solution by UV-TiO2-Fe(VI

    Directory of Open Access Journals (Sweden)

    Yan Ma

    2015-01-01

    Full Text Available The photocatalytic degradation of sulfonamides in aqueous TiO2 suspension under UV irradiation has been investigated using potassium ferrate as electron acceptors. The results showed that the stability of Fe(VI is dependent on pH significantly, and the stability reduces obviously in the presence of UV-TiO2. The experiments indicated that Fe(VI could effectively scavenge the conduction band electrons from the surface of TiO2. The photocatalytic oxidation of sulfonamides with Fe(VI was found to be much faster than that without Fe(VI. The SD, SM, and SMX concentration was greatly reduced by 89.2%, 83.4%, and 82.0%, respectively, after 10 min with UV-TiO2-Fe(VI, comparing to 65.2%, 66.0%, and 71.9%, respectively, with Fe(VI only in the dark and 71.3%, 72.7%, and 76.0%, respectively, with UV-TiO2. The pH value of solution significantly influenced the sulfonamides degradation in UV-TiO2-Fe(VI system. The degradation amount of sulfonamides after 10 min was a maximum at pH 7. The intermediate products of sulfonamides oxidation by UV-TiO2-Fe(VI were analysed by LC-HESI-MS-MS and the results suggested that a majority of sulfonamides turned into large-molecule products without complete mineralization.

  14. Sandstone Turning by Abrasive Waterjet

    Czech Academy of Sciences Publication Activity Database

    Hlaváček, Petr; Cárach, J.; Hloch, Sergej; Vasilko, K.; Klichová, Dagmar; Klich, Jiří; Lehocká, D.

    2015-01-01

    Roč. 48, č. 6 (2015), s. 2489-2493 ISSN 0723-2632 R&D Projects: GA MŠk ED2.1.00/03.0082; GA MŠk(CZ) LO1406 Institutional support: RVO:68145535 Keywords : turning away from the jet * conventional turning towards the jet * sandstone * abrasive water jet Subject RIV: JQ - Machines ; Tools Impact factor: 2.386, year: 2015 http://www.springerprofessional.de/sandstone-turning-by-abrasive-waterjet/6038028.html

  15. Two new beta-strand mimics.

    Science.gov (United States)

    Tsai, J H; Waldman, A S; Nowick, J S

    1999-01-01

    In a previous report, Nowick and co-workers described beta-strand mimic A, which duplicates the structure and hydrogen-bonding pattern of one edge of a tetrapeptide in a beta-strand conformation (Nowick, J. S.; Pairish, M.; Lee, I. Q.; Holmes, D. L.; Ziller, J. W. J. Am. Chem. Soc. 1997, 119, 5413). Beta-strand mimic A is composed of a 5-amino-2-methoxybenzoic acid unit linked to a 5-hydrazino-2-methoxybenzamide unit by means of an acylhydrazine group. This paper introduces two related beta-strand mimics (B and C) and reports their comparison to beta-strand mimic A. Beta-strand mimic B is composed of a 5-amino-2-methoxybenzoic acid unit linked by a diacylhydrazine group to a fumaramide unit; beta-strand mimic C is composed of a 5-amino-2-methoxybenzoic acid unit linked by a diacylhydrazine group to a peptide. Beta-strand mimics A-C were connected to tripeptide (Phe-Ile-Leu) groups by means of 1,2-diaminoethane diurea turn units to form artificial beta-sheets 1-3. 1H NMR studies, involving ROESY, chemical shift, coupling constant, and variable temperature experiments, reveal that 1-3 adopt hydrogen-bonded antiparallel beta-sheet conformations and establish that all three templates are viable beta-strand mimics.

  16. Protostars and Planets VI

    Science.gov (United States)

    Beuther, Henrik; Klessen, Ralf S.; Dullemond, Cornelis P.; Henning, Thomas

    star and planet formation. They are used by students to dive into new topics, and they are much valued by experienced researchers as a comprehensive overview of the field with all its interactions. We hope that you will enjoy reading (and learning from) this book as much as we do. The organization of the Protostars and Planets conference was carried out in close collaboration between the Max Planck Institute for Astronomy and the Center for Astronomy of the University Heidelberg, with generous support from the German Science Foundation. This volume is a product of effort and care by many people. First and foremost, we want to acknowledge the 250 contributing authors, as it is only due to their expertise and knowledge that such a comprehensive review compendium in all its depth and breadth is possible. The Protostars and Planets VI conference and this volume was a major undertaking, with support and contributions by many people and institutions. We like to thank the members of the Scientific Advisory Committee who selected the 38 teams and chapters out of more than 120 submitted proposals. Similarly, we are grateful to the reviewers, who provided valuable input and help to the chapter authors. The book would also not have been possible without the great support of Renée Dotson and other staff from USRA’s Lunar and Planetary Institute, who handled the detailed processing of all manuscripts and the production of the book, and of Allyson Carter and other staff from the University of Arizona Press. We are also grateful to Richard Binzel, the General Editor of the Space Science Series, for his constant support during the long process, from the original concept to this final product. Finally, we would like to express a very special thank you to the entire conference local organizing committee, and in particular, Carmen Cuevas and Natali Jurina, for their great commitment to the project and for a very fruitful and enjoyable collaboration.

  17. VI Tallinna arhitektuuritriennaal / Leonhard Lapin

    Index Scriptorium Estoniae

    Lapin, Leonhard, 1947-

    2005-01-01

    15.-17. IX Tallinnas Niguliste kirikus toimuval VI Tallinna arhitektuuritriennaalil esinevad inglise arhitektuurikriitik Peter Davey, šveitsi arhitekt Peter Zumthor, soome arhitekt Juha Leviskä, eesti arhitekt Vilen Künnapu, eesti kunstiajaloolane Juhan Maiste jt. Külastatakse KUMU, tutvutab autor Pekka Vapaavuori

  18. (VI) oxide in acetic acid

    African Journals Online (AJOL)

    The oxidation of cyclohexene by chromium (VI) oxide in aqueous and acetic media was studied. The reaction products were analysed using infra red (IR) and gas chromatography coupled with mass (GC/MS) spectroscopy. The major products of the oxidation reaction in acetic acid medium were cyclohexanol, ...

  19. A Turning Point for Literacy

    Science.gov (United States)

    Literacy Work, 1977

    1977-01-01

    Discusses the publication "A Turning Point for Literacy" edited by Leon Bataille, and based on information from the International Symposium for Literacy (1975). The author notes that the document represents the complete history and background of literacy from the point of departure in 1965 to a turning point in 1975. (TA)

  20. Beta vulgaris

    African Journals Online (AJOL)

    Heat treated Beetroot have the highest value for ABTS scavenging ability. ... powdered sample was stored in a clean dry plastic container at room ..... Nutritional value and economic feasibility of red beetroot. (Beta vulgaris L. ssp. vulgaris Rote Kugel) from different production systems. African Journal of. Agricultural ...

  1. Turns and maneuvers during swimming

    Science.gov (United States)

    Bhalla, Amneet; Mosberg, Noah; Bale, Rahul; Patankar, Neelesh

    2011-11-01

    In this work we use fully resolved fluid dynamics computations based on an immersed body approach to study fish turns and maneuvers. We present a numerical method to control the trajectory of fish during turns and maneuvers. Fish tracking a prey is presented as an example case. Numerical simulations are carried out on spatially adaptive grid for speed and accuracy. The effect of deformation kinematics and Reynolds number (Re), on the turn radius of an undulatory swimmer, is studied. Power spent during turning at different turn radii and Re is also reported. These results can be used to quantify the cost of various maneuvers and to identify efficient maneuvers to attain the same objective, e.g., reaching a target location during prey tracking. NSF support is gratefully acknowledged.

  2. 29 CFR 1926.1126 - Chromium (VI).

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Chromium (VI). 1926.1126 Section 1926.1126 Labor... Chromium (VI). (a) Scope. (1) This standard applies to occupational exposures to chromium (VI) in all forms... objective data demonstrating that a material containing chromium or a specific process, operation, or...

  3. 29 CFR 1915.1026 - Chromium (VI).

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Chromium (VI). 1915.1026 Section 1915.1026 Labor... § 1915.1026 Chromium (VI). (a) Scope. (1) This standard applies to occupational exposures to chromium (VI... cement; or (4) Where the employer has objective data demonstrating that a material containing chromium or...

  4. Turning collectors for solar radiation

    Science.gov (United States)

    Barak, Amitzur Z.

    1976-01-01

    A device is provided for turning a solar collector about the polar axis so that the collector is directed toward the sun as the sun tracks the sky each day. It includes two heat-expansive elements and a shadow plate. In the morning a first expansive element is heated, expands to turn the collector to face the sun, while the second expansive element is shaded by the plate. In the afternoon the second element is heated, expands to turn the collector to face the sun, while the first is shaded by the plate.

  5. Turning around Newton's Second Law

    Science.gov (United States)

    Goff, John Eric

    2004-01-01

    Conceptual and quantitative difficulties surrounding Newton's second law often arise among introductory physics students. Simply turning around how one expresses Newton's second law may assist students in their understanding of a deceptively simple-looking equation.

  6. Hvad bruger vi tiden til?

    DEFF Research Database (Denmark)

    Brichet, Nathalia Sofie; Hastrup, Frida

    2016-01-01

    I denne artikel kaster vi et antropologisk blik på samtidsarkæologi ved at diskutere måder, hvorpå antropologiske analyser kan adressere tid, fortidige hændelser og historiske processer. Vi argumenterer for, at en radikal nutidsorientering er en afgørende kvalitet ved det antropologiske feltarbej...... komplicerer en ide om fortidige (gamle eller nyere) objekter som nogle, der kan udgraves......., hvis sigte det er løbende at generere sit materiale nu og her med henblik på at skabe nye forståelser, historier og forslag til mangeartede sammenhænge. En implikation af dette er, at uanset hvor ’historisk’ et antropologisk materiale end måtte være, må det altid ses som samtidigt og ufærdigt, hvilket...

  7. What 'empirical turn in bioethics'?

    Science.gov (United States)

    Hurst, Samia

    2010-10-01

    Uncertainty as to how we should articulate empirical data and normative reasoning seems to underlie most difficulties regarding the 'empirical turn' in bioethics. This article examines three different ways in which we could understand 'empirical turn'. Using real facts in normative reasoning is trivial and would not represent a 'turn'. Becoming an empirical discipline through a shift to the social and neurosciences would be a turn away from normative thinking, which we should not take. Conducting empirical research to inform normative reasoning is the usual meaning given to the term 'empirical turn'. In this sense, however, the turn is incomplete. Bioethics has imported methodological tools from empirical disciplines, but too often it has not imported the standards to which researchers in these disciplines are held. Integrating empirical and normative approaches also represents true added difficulties. Addressing these issues from the standpoint of debates on the fact-value distinction can cloud very real methodological concerns by displacing the debate to a level of abstraction where they need not be apparent. Ideally, empirical research in bioethics should meet standards for empirical and normative validity similar to those used in the source disciplines for these methods, and articulate these aspects clearly and appropriately. More modestly, criteria to ensure that none of these standards are completely left aside would improve the quality of empirical bioethics research and partly clear the air of critiques addressing its theoretical justification, when its rigour in the particularly difficult context of interdisciplinarity is what should be at stake.

  8. Active peptidomimetic insect kinin analogs with type VI turn motif 4-aminopyroglutamate lack native peptide bonds

    Science.gov (United States)

    Two stereochemical variant insect kinin mimetic analogs 1796 and 1797 containing (2S,4S)-APy (APy) and (2R,4S)-APy (Apy), respectively, were synthesized and evaluated on isolated Malpighian tubules of the house cricket Acheta domesticus to determine if they could retain the fluid secretion stimulat...

  9. Har vi brug for hovedregning?

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye

    2015-01-01

    Hvor ofte har vi brug for at regne noget i hoved? Har de fleste af os ikke altid et elektronisk hjælpemiddel ved hånden enten som en lille lommeregner eller telefonen? Selvom det umiddelbart kan synes unødvendigt at træne hovedregning, viser det sig, at netop træning af hovedregning støtter...... udvikling af hurtige regnestrategier, hvorfor det faktisk er en god ide at investere tid og energi i at træne netop dette....

  10. Interaction of uranium(VI) with bioligands present in human biological fluids. The case study of urea and uric acid

    Energy Technology Data Exchange (ETDEWEB)

    Osman, A.A.A.; Geipel, G.; Bernhard, G. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany). Inst. of Resource Ecology

    2013-05-01

    The complexation of uranium(VI) with bioligands found in human biological fluids, viz, urea and uric acid in aqueous solutions, has been investigated using time-resolved laser-induced fluorescence spectroscopy (TRLFS) at room temperature, I = 0.1 M (NaClO4) and pH (3 for uric acid; 4 for urea). In both complex systems a static quench effect with increasing ligand concentration and no peaks shift upon complexation were observed. With uranium(VI) both ligands formed a fairly weak 1:1 complex with average stability constants of log {beta}{sub 110} = 4.67 {+-} 0.29 for uric acid and log {beta}{sub 110} = 3.79 {+-} 0.15 and 2.12 {+-} 0.18 for relatively low and relatively high urea concentrations, respectively. Application of the newly generated data on the U(VI) speciation modelling in biofluids, e.g., human urine was also discussed.

  11. The Physics of Ski Turns

    Science.gov (United States)

    Shonle, John I.; Nordick, Douglas L.

    1972-01-01

    Describes the application of basic dynamics of rotations to the case of turning on skis, first without and then with external torques. Various elements are combined in different techniques and suggestions for further extensions and a list of laboratory exercises based on skiing are included. (DF)

  12. The Philosophy of Turning Points

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    2013-01-01

    This paper introduces and discusses the concept of turning points from the ontological, epistemological, and methodological perspectives, applying it to the de-internationalization phenomenon to exemplify its deployment. As a concept that adds to the variance and complexity of the international b...... of a generalizable international business and management theory....

  13. Professional Employees Turn to Unions

    Science.gov (United States)

    Chamot, Dennis

    1976-01-01

    White-collar and professional employees are increasingly turning to unions to combat their loss of independence as employees of large organizations. Managers should realize that they and professional employees have different viewpoints about job situations and that the current trend toward white-collar unionism is apt to continue. (JG)

  14. Hamilton's theory of turns revisited

    Indian Academy of Sciences (India)

    Hamilton's theory of turns, arising out of his profound and more general theory of quaternions, gives a beautiful geometric visualization of the elements of the groups. SO(3) and SU(2), and of their noncommutative composition laws [1]. Thus, group elements can be pictured as equivalence classes of directed great circle arcs ...

  15. Hamilton's theory of turns revisited

    Indian Academy of Sciences (India)

    We present a new approach to Hamilton's theory of turns for the groups (3) and (2) which renders their properties, in particular their composition law, nearly trivial and immediately evident upon inspection. We show that the entire construction can be based on binary rotations rather than mirror reflections.

  16. Turn Management or Impression Management?

    NARCIS (Netherlands)

    ter Maat, Mark; Heylen, Dirk K.J.; Ruttkay, Z.M.; Kipp, M.; Nijholt, Antinus; Vilhjálmsson, H.H.

    2009-01-01

    We look at how some basic choices in the management of turns influence the impression that people get from an agent. We look at scales concerning personality, emotion and interpersonal stance. We do this by a person perception study, or rather an agent perception study, using simulated conversations

  17. Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

    DEFF Research Database (Denmark)

    Nygaard, Rie; Hansen, Louise Valentin; Mokrosinski, Jacek

    2010-01-01

    Five highly conserved polar residues connected by a number of structural water molecules together with two rotamer micro-switches, TrpVI:13 and TyrVII:20, constitute an extended hydrogen bond network between the intracellular segments of TM-I, -II, -VI, and -VII of 7TM receptors. Molecular dynamics...... simulations showed that, although the fewer water molecules in rhodopsin were relatively movable, the hydrogen bond network of the beta2-adrenergic receptor was fully loaded with water molecules that were surprisingly immobilized between the two rotamer switches, both apparently being in their closed...... conformation. Manipulations of the rotamer state of TyrVII:20 and TrpVI:13 demonstrated that these residues served as gates for the water molecules at the intracellular and extracellular ends of the hydrogen bond network, respectively. TrpVI:13 at the bottom of the main ligand-binding pocket was shown...

  18. Vi tror ikke noget, vi undersøger det

    DEFF Research Database (Denmark)

    Hansen, Gitte Riis; Winther Johannsen, Inger

    2017-01-01

    I diskussionerne om, hvad der kan betegnes som god viden i forhold til udvikling af pædagogisk ud-vikling og kvalitet, er yderpunkterne kridtet op. Begreber som ”evidensbaseret” og ”datainformeret” synes at udfordre det pædagogiske felts egen forståelse af faglighed og pædagogisk kvalitet. I proj...... tager afsæt i det konkrete projekt og samarbejdet med døgntilbuddene. Vi viser, at arbejdet med datainformeret metode på denne måde ikke er en udradering af pædagogisk faglighed knyttet til fagprofessionel dømmekraft – snarere tværtimod...

  19. Diamond turning machine controller implementation

    Energy Technology Data Exchange (ETDEWEB)

    Garrard, K.P.; Taylor, L.W.; Knight, B.F.; Fornaro, R.J.

    1988-12-01

    The standard controller for a Pnuemo ASG 2500 Diamond Turning Machine, an Allen Bradley 8200, has been replaced with a custom high-performance design. This controller consists of four major components. Axis position feedback information is provided by a Zygo Axiom 2/20 laser interferometer with 0.1 micro-inch resolution. Hardware interface logic couples the computers digital and analog I/O channels to the diamond turning machine`s analog motor controllers, the laser interferometer, and other machine status and control information. It also provides front panel switches for operator override of the computer controller and implement the emergency stop sequence. The remaining two components, the control computer hardware and software, are discussed in detail below.

  20. Opposed turns at signalized intersections

    Energy Technology Data Exchange (ETDEWEB)

    Akcelik, R.

    1989-06-01

    The 1985 Highway Capacity Manual (HCM) brought the U.S. and Australian methodologies for signalized intersections closer together. An important element in this methodology is the techniques used for the estimation of opposed (permissive) turn saturation flows. Although the basic modeling philosophies of the HCM and Australian methods are similar, there are significant differences in the procedures used and therefore in the results from the two methods. In particular, the latest methodology employed in the SIDRA software has eliminated the use of opposed turn adjustment factors for lane groups and adopted an explicit and direct method of modeling individual lanes. The purpose of this paper is to bring these new methods to the attention of the U.S. researchers since it is understood that efforts are being made to improve the 1985 HCM method.

  1. Transparent lattice characterization with gated turn-by-turn data of diagnostic bunch train

    Science.gov (United States)

    Li, Yongjun; Cheng, Weixing; Ha, Kiman; Rainer, Robert

    2017-11-01

    Methods of characterization of a storage ring's lattice have traditionally been intrusive to routine operations. More importantly, the lattice seen by particles can drift with the beam current due to collective effects. To circumvent this, we have developed a novel approach for dynamically characterizing a storage ring's lattice that is transparent to operations. Our approach adopts a dedicated filling pattern which has a short, separate diagnostic bunch train (DBT). Through the use of a bunch-by-bunch feedback system, the DBT can be selectively excited on demand. Gated functionality of a beam position monitor system is capable of collecting turn-by-turn data of the DBT, from which the lattice can then be characterized after excitation. As the DBT comprises only about one percent of the total operational bunches, the effects of its excitation are negligible to users. This approach allows us to localize the distributed quadrupolar wakefields generated in the storage ring vacuum chamber during beam accumulation. While effectively transparent to operations, our approach enables us to dynamically control the beta beat and phase beat, and unobtrusively optimize performance of the National Synchrotron Light Source-II accelerator during routine operations.

  2. Transparent lattice characterization with gated turn-by-turn data of diagnostic bunch train

    Directory of Open Access Journals (Sweden)

    Yongjun Li

    2017-11-01

    Full Text Available Methods of characterization of a storage ring’s lattice have traditionally been intrusive to routine operations. More importantly, the lattice seen by particles can drift with the beam current due to collective effects. To circumvent this, we have developed a novel approach for dynamically characterizing a storage ring’s lattice that is transparent to operations. Our approach adopts a dedicated filling pattern which has a short, separate diagnostic bunch train (DBT. Through the use of a bunch-by-bunch feedback system, the DBT can be selectively excited on demand. Gated functionality of a beam position monitor system is capable of collecting turn-by-turn data of the DBT, from which the lattice can then be characterized after excitation. As the DBT comprises only about one percent of the total operational bunches, the effects of its excitation are negligible to users. This approach allows us to localize the distributed quadrupolar wakefields generated in the storage ring vacuum chamber during beam accumulation. While effectively transparent to operations, our approach enables us to dynamically control the beta beat and phase beat, and unobtrusively optimize performance of the National Synchrotron Light Source-II accelerator during routine operations.

  3. Diamond turning of thermoplastic polymers

    Energy Technology Data Exchange (ETDEWEB)

    Smith, E.; Scattergood, R.O.

    1988-12-01

    Single point diamond turning studies were made using a series of thermoplastic polymers with different glass transition temperatures. Variations in surface morphology and surface roughness were observed as a function of cutting speed. Lower glass transition temperatures facilitate smoother surface cuts and better surface finish. This can be attributed to the frictional heating that occurs during machining. Because of the very low glass transition temperatures in polymeric compared to inorganic glasses, the precision machining response can be very speed sensitive.

  4. Right turn on red (RTOR)

    OpenAIRE

    Vovk, Žiga

    2013-01-01

    The subject of this thesis is introducing the principle of law permitting right turn on red (in further RTOR) and seeking procedures for better level of service in traffic intersections. In the first part, the work talks about history and usage of the RTOR around the world. Afterwards it focuses on research data from and about traffic accidents, benefits and disadvantages, and dangerous situations occurred because of the RTOR. Thesis concludes with principles of RTOR adjusted for Slovenia inc...

  5. Mens vi venter på finansloven ..

    DEFF Research Database (Denmark)

    Madsen, Mogens Ove

    2011-01-01

    Vi må dog lufte en forsigtig optimisme over, at der kom signaler om opgør med detailstyring og knopskydningen af øremærket forskning.......Vi må dog lufte en forsigtig optimisme over, at der kom signaler om opgør med detailstyring og knopskydningen af øremærket forskning....

  6. Når vi taler om 68

    DEFF Research Database (Denmark)

    Jensen, Henrik; Metz, Georg

    Når vi taler om 68 er en intellektuel samtale mellem to ligeværdige gentlemen og skallesmækkere. En essayistisk dyst om porno, RAF, Pittelkow og livsfilosofi......Når vi taler om 68 er en intellektuel samtale mellem to ligeværdige gentlemen og skallesmækkere. En essayistisk dyst om porno, RAF, Pittelkow og livsfilosofi...

  7. MURALS WITH A ViBe

    National Research Council Canada - National Science Library

    Drake, Leigh

    2017-01-01

    The ViBe District in Virginia Beach is a hub for the local arts community. There is a fenced area in the ViBe District that features a whole row of murals created by professional artists, amateurs, and student groups from all over...

  8. Econophys-Kolkata VI Conference

    CERN Document Server

    Chakrabarti, Bikas; Chakraborti, Anirban; Ghosh, Asim

    2013-01-01

    The primary goal of the book is to present the ideas and research findings of active researchers such as physicists, economists, mathematicians and financial engineers working in the field of “Econophysics,” who have undertaken the task of modeling and analyzing systemic risk, network dynamics and other topics. Of primary interest in these studies is the aspect of systemic risk, which has long been identified as a potential scenario in which financial institutions trigger a dangerous contagion mechanism, spreading from the financial economy to the real economy. This type of risk, long confined to the monetary market, has spread considerably in the recent past, culminating in the subprime crisis of 2008. As such, understanding and controlling systemic risk has become an extremely important societal and economic challenge. The Econophys-Kolkata VI conference proceedings are dedicated to addressing a number of key issues involved. Several leading researchers in these fields report on their recent work and al...

  9. Dissimilatory Reduction of Cr(VI), Fe(III), and U(VI) by Cellulomonas Isolates

    Energy Technology Data Exchange (ETDEWEB)

    Smith, William Aaron; Apel, William Arnold; Peyton, B. M.; Petersen, J. N.; Sani, R.

    2002-10-01

    The reduction of Cr(VI), Fe(III), and U(VI) was studied using three recently isolated environmental Cellulomonas sp. (WS01, WS18, and ES5) and a known Cellulomonas strain (Cellulomonas flavigena ATCC 482) under anaerobic, non-growth conditions. In all cases, these cultures were observed to reduce Cr(VI), Fe(III), and U(VI). In 100 h, with lactate as electron donor, the Cellulomonas isolates (500 mg/l total cell protein) reduced nitrilotriacetic acid chelated Fe(III) [Fe(III)-NTA] from 5 mM to less than 2.2 mM, Cr(VI) from 0.2 mM to less than 0.001 mM, and U(VI) from 0.2 mM to less than 0.12 mM. All Cellulomonas isolates also reduced Cr(VI), Fe(III), and U(VI) in the absence of lactate, while no metal reduction was observed in either the cell-free or heat-killed cell controls. This is the first report of Cellulomonas sp. reducing Fe(III) and U(VI). Further, this is the first report of Cellulomonas spp. coupling the oxidation of lactate, or other unknown electron donors in the absence of lactate, to the reduction of Cr(VI), Fe(III), and U(VI).

  10. Dissimilatory reduction of Cr(VI), Fe(III), and U(VI) by Cellulomonas isolates.

    Science.gov (United States)

    Sani, R K; Peyton, B M; Smith, W A; Apel, W A; Petersen, J N

    2002-10-01

    The reduction of Cr(VI), Fe(III), and U(VI) was studied using three recently isolated environmental Cellulomonas sp. (WS01, WS18, and ES5) and a known Cellulomonas strain ( Cellulomonas flavigena ATCC 482) under anaerobic, non-growth conditions. In all cases, these cultures were observed to reduce Cr(VI), Fe(III), and U(VI). In 100 h, with lactate as electron donor, the Cellulomonas isolates (500 mg/l total cell protein) reduced nitrilotriacetic acid chelated Fe(III) [Fe(III)-NTA] from 5 mM to less than 2.2 mM, Cr(VI) from 0.2 mM to less than 0.001 mM, and U(VI) from 0.2 mM to less than 0.12 mM. All Cellulomonas isolates also reduced Cr(VI), Fe(III), and U(VI) in the absence of lactate, while no metal reduction was observed in either the cell-free or heat-killed cell controls. This is the first report of Cellulomonas sp. reducing Fe(III) and U(VI). Further, this is the first report of Cellulomonas spp. coupling the oxidation of lactate, or other unknown electron donors in the absence of lactate, to the reduction of Cr(VI), Fe(III), and U(VI).

  11. Genetics Home Reference: collagen VI-related myopathy

    Science.gov (United States)

    ... Twitter Home Health Conditions Collagen VI-related myopathy Collagen VI-related myopathy Printable PDF Open All Close ... Javascript to view the expand/collapse boxes. Description Collagen VI-related myopathy is a group of disorders ...

  12. Finite difference simulation of biological chromium (VI) reduction in ...

    African Journals Online (AJOL)

    (VI) concentration profiles inside porous aquifer media columns. The model was thereafter used to calculate Cr(VI) removal rate for a range of Cr(VI) loadings. Internal concentration profiles were modelled against data collected from ...

  13. Beta Emission and Bremsstrahlung

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-13

    Bremsstrahlung is continuous radiation produced by beta particles decelerating in matter; different beta emitters have different endpoint energies; high-energy betas interacting with high-Z materials will more likely produce bremsstrahlung; depending on the data, sometimes all you can say is that a beta emitter is present.

  14. The affective turn in ethnomusicology

    Directory of Open Access Journals (Sweden)

    Hofman Ana

    2015-01-01

    Full Text Available The affective turn, which has already questioned dominant paradigms in many disciplinary fields including cultural studies, philosophy, political theory, anthropology, psychology and neuroscience, has started to attract more attention in the field of ethnomusicology, becoming a particularly vibrant stream of thought. Drawing on the voices that call for the historicisation of and critical deliberation on the field of affect studies, the article strives to show how theories of affect might expand dominant paradigms in ethnomusicology and also points to their limitations.

  15. Forward-Looking Betas

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Vainberg, Gregory

    -looking. This paper introduces a radically different approach to estimating market betas. Using the tools in Bakshi and Madan (2000) and Bakshi, Kapadia and Madan (2003) we employ the information embedded in the prices of individual stock options and index options to compute our forward-looking market beta......-looking betas contain information relevant for forecasting future betas that is not contained in historical betas....

  16. Emissions of chromium (VI) from arc welding.

    Science.gov (United States)

    Heung, William; Yun, Myoung-Jin; Chang, Daniel P Y; Green, Peter G; Halm, Chris

    2007-02-01

    The presence of Cr in the +6 oxidation state (Cr[VI]) is still observed in ambient air samples in California despite steps taken to reduce emissions from plating operations. One known source of emission of Cr(VI) is welding, especially with high Cr-content materials, such as stainless steels. An experimental effort was undertaken to expand and update Cr(VI) emission factors by conducting tests on four types of arc-welding operations: gas-metal arc welding (GMAW), shielded metal arc welding (SMAW), fluxcore arc welding, and pulsed GMAW. Standard American Welding Society hood results were compared with a total enclosure method that permitted isokinetic sampling for particle size-cut measurement, as well as total collection of the aerosol. The fraction of Cr(VI) emitted per unit mass of Cr electrode consumed was determined. Consistent with AP-42 data, initial results indicate that a significant fraction of the total Cr in the aerosol is in the +6 oxidation state. The fraction of Cr(VI) and total aerosol mass produced by the different arc welding methods varies with the type of welding process used. Self-shielded electrodes that do not use a shield gas, for example, SMAW, produce greater amounts of Cr(VI) per unit mass of electrode consumed. The formation of Cr(VI) from standard electrode wires used for welding mild steel was below the method detection limit after eliminating an artifact in the analytical method used.

  17. Anaerobic bio-removal of uranium (VI) and chromium (VI): Comparison of microbial community structure

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Monica [Centro de Ciencias do Mar, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro (Portugal); Faleiro, Maria Leonor [IBB - Centro de Biomedicina Molecular e Estrutural, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro (Portugal); Chaves, Sandra; Tenreiro, Rogerio [Universidade de Lisboa, Faculdade de Ciencias, Centro de Biodiversidade, Genomica Integrativa e Funcional (BioFIG), Campus de FCUL, Campo Grande 1749-016 Lisboa (Portugal); Santos, Erika [Centro de Ciencias do Mar, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro (Portugal); Costa, Maria Clara, E-mail: mcorada@ualg.pt [Centro de Ciencias do Mar, Universidade do Algarve, Campus de Gambelas, 8005-139 Faro (Portugal)

    2010-04-15

    Several microbial communities, obtained from uranium contaminated and non-contaminated samples, were investigated for their ability to remove uranium (VI) and the cultures capable for this removal were further assessed on their efficiency for chromium (VI) removal. The highest efficiency for removal of both metals was observed on a consortium from a non-contaminated soil collected in Monchique thermal place, which was capable to remove 91% of 22 mg L{sup -1} U(VI) and 99% of 13 mg L{sup -1} Cr(VI). This study revealed that uranium (VI) removing communities have also ability to remove chromium (VI), but when uranium (VI) was replaced by chromium (VI) several differences in the structure of all bacterial communities were observed. TGGE and phylogenetic analysis of 16S rRNA gene showed that the uranium (VI) removing bacterial consortia are mainly composed by members of Rhodocyclaceae family and Clostridium genus. On the other hand, bacteria from Enterobacteriaceae family were detected in the community with ability for chromium (VI) removal. The existence of members of Enterobacteriaceae and Rhodocyclaceae families never reported as chromium or uranium removing bacteria, respectively, is also a relevant finding, encouraging the exploitation of microorganisms with new abilities that can be useful for bioremediation.

  18. Learning the vi and Vim Editor

    CERN Document Server

    Robbins, Arnold; Hannah, Elbert

    2008-01-01

    There's nothing that hard-core Unix and Linux users are more fanatical about than their text editor. Editors are the subject of adoration and worship, or of scorn and ridicule, depending upon whether the topic of discussion is your editor or someone else's. vi has been the standard editor for close to 30 years. Popular on Unix and Linux, it has a growing following on Windows systems, too. Most experienced system administrators cite vi as their tool of choice. And since 1986, this book has been the guide for vi. However, Unix systems are not what they were 30 years ago, and neither is this

  19. Mucopolissacaridose tipo VI: relato de caso

    OpenAIRE

    Lais Orosco Bialon Santana; Carolina Ando Matsuno; Marta Wey Vieira

    2014-01-01

    Introdução: As mucopolissacaridoses são erros inatos do metabolismo de depósito lisossomal subclassificadas segundo a enzima deficiente. A arilsulfatase B (ARSB), responsável por degradar os glicosaminoglicanos (GAGs), que atuam no tecido conjuntivo, é deficiente na mucopolissacaridose tipo VI (MP VI). A MP VI tem clínica variável, sem anormalidades ao nascimento, evidenciando-se progressivamente ao acúmulo de GAGs. O diagnóstico se faz pela redução da atividade da ARSB ou da mutação genética...

  20. Turning CSR on it's head

    DEFF Research Database (Denmark)

    Kampf, Constance Elizabeth

    their ecological footprint. Then CarrotMob members use social media to recruit as many customers as possible to shop at that time, thus increasing both profits and available resources for the business to engage in sustainability. As sustainability and CSR are enacted differently in the US and EU (Matten and Moon....... However, from a technology perspective, Howe (2009) argues that the boundaries of the firm are becoming porous, and through social media people are contributing some of their best energy for free. These technology empowered stakeholders can be resources for strategy when the firm is seen as having porous......, rather than impermeable boundaries. Thus, social and mobile media can be approached as a force that works at further eroding boundaries between the firm and technology empowered individuals equipped with their personal agendas and social media capital. As an example of social media turning tradition...

  1. Visualisation turns down energy demand

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Ole Michael [Danish Building and Urban Research, Hoersholm (Denmark)

    2003-07-01

    After many energy saving campaigns, Danish families give the impression that they are conscious of energy consumption. Children have learned to turn off the light and adults to buy low-energy bulbs and household appliances. Questioned about their energy consumption and its fluctuations, the same people nevertheless confess to not really knowing. You pay your energy bill but pay no attention to the current consumption, or its level. Unlike other types of consumption, energy consumption is an almost invisible type of consumption. Nevertheless, as a secondary consumption it is much affected by primary consumption in the form of white goods, appliances, cars, food etc., the main purpose of which usually is visibility. This paper presents the result of an experiment to make the energy consumption visible. Meters in the flats showing actual electricity, heat and water consumption confront tenants with the consequences of their own behaviour. The experiment also investigates different set-ups concerning information and communication about energy consumption. Monthly consumption and levels of consumption compared within the neighbourhood are elements of this information. Also quarterly eco-accounting, with key-figures of consumption and environmental considerations like CO{sub 2} emission, are part of the information set-up. Within the first year of visualisation one case shows a 9% reduction of heat and a 22% reduction of electricity. The other cases seem to follow the same tendency. The philosophy of the experiment is that you must know your position in order to change it. You must know about the level of your own energy consumption in order to turn down energy demand. The visible meters are elements in 'Urban Ecological Renewal of a Housing Block' (Hedebygade Block) in a central district of Copenhagen.

  2. ViSIT: Visitor Survey Information Tool

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — ViSIT is an interactive web tool created by USGS to visualize the data collected as part of the National Wildlife Refuge Visitor Survey. The national survey was...

  3. Derfor elsker og hader vi positiv psykologi

    DEFF Research Database (Denmark)

    Mehlsen, Camilla

    2010-01-01

    Hvorfor er positiv psykologi så populært? Er positiv psykologi ved at blive en religion? Asterisk har mødt tre fremtrædende forskere, der forklarer, hvorfor vi elsker og hader positiv psykolog.......Hvorfor er positiv psykologi så populært? Er positiv psykologi ved at blive en religion? Asterisk har mødt tre fremtrædende forskere, der forklarer, hvorfor vi elsker og hader positiv psykolog....

  4. Kan vi forebygge en kompliceret sorgreaktion?

    DEFF Research Database (Denmark)

    Nielsen, Mette Kjærgaard; Guldin, Mai-Britt

    2017-01-01

    Pårørende til alvorligt syge patienter er i en sårbar situation og risikerer selv at blive syge. Som sundhedsprofessionelle har vi mulighed for at støtte pårørende i palliative forløb, og vi vil i denne artikel beskrive mulige prædiktorer for kompliceret sorg og depression hos den pårørende efter...

  5. Hvad skal vi med Trump-satire?

    DEFF Research Database (Denmark)

    Møller, Mette

    2017-01-01

    Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til? Link: http://videnskab.dk/kultur-samfund/hvad-skal-vi-med-trump-satire...

  6. SaVi: satellite constellation visualization

    OpenAIRE

    Wood, Lloyd

    2012-01-01

    SaVi, a program for visualizing satellite orbits, movement, and coverage, is maintained at the University of Surrey. This tool has been used for research in academic papers, and by industry companies designing and intending to deploy satellite constellations. It has also proven useful for demonstrating aspects of satellite constellations and their geometry, coverage and movement for educational and teaching purposes. SaVi is introduced and described briefly here.

  7. Next speakers plan their turn early and speak after turn-final "go-signals"

    NARCIS (Netherlands)

    Barthel, M.; Meyer, A.S.; Levinson, S.C.

    2017-01-01

    In conversation, turn-taking is usually fluid, with next speakers taking their turn right after the end of the previous turn. One reason for this fluency is early content planning of the next turn, if possible while the current turn is still coming in, as found by Barthel et al. (2016) using the

  8. William Friedman, Geneticist Turned Cryptographer.

    Science.gov (United States)

    Goldman, Irwin L

    2017-05-01

    William Friedman (1891-1969), trained as a plant geneticist at Cornell University, was employed at Riverbank Laboratories by the eccentric millionaire George Fabyan to work on wheat breeding. Friedman, however, soon became intrigued by and started working on a pet project of Fabyan's involving the conjecture that Francis Bacon, a polymath known for the study of ciphers, was the real author of Shakespeare's plays. Thus, beginning in ∼1916, Friedman turned his attention to the so called "Baconian cipher," and developed decryption techniques that bore similarity to approaches for solving problems in population genetics. His most significant, indeed pathbreaking, work used ideas from genetics and statistics, focusing on analysis of the frequencies of letters in language use. Although he had transitioned from being a geneticist to a cryptographer, his earlier work had resonance in his later pursuits. He soon began working directly for the United States government and produced solutions used to solve complex military ciphers, in particular to break the Japanese Purple code during World War II. Another important legacy of his work was the establishment of the Signal Intelligence Service and eventually the National Security Agency. Copyright © 2017 by the Genetics Society of America.

  9. Notes on the Spatial Turn

    Directory of Open Access Journals (Sweden)

    Stipe Grgas

    2012-06-01

    Full Text Available On the basis of ever-mounting evidence, amongst which is the “zone” problematic of the Zadar conference that occassioned these notes, it can be concluded that the spatial turn has insinuated itself as an all-pervading heuristic tool throughout the humanities and the social sciences. The extent to which space and spatiality have usurped the central stage in the various branches of reasearch can be gauged by admonishments that what we are witnessing is a new fundamentalism that has simply inverted the terms of the dualism of time and space (May and Thrift 2001: “Introduction”. According to Michael Dear the sway of space is manifested in multifold ways: in the ubiquity of spatial analysis in social theories and practices; in the explosion of publications devoted to the exploration of the interface of the social and the spatial; in the reintegration of human geography into various domains of knowledge; in the focus given to difference and the consequent diversification of theoretical and empirical practices; in a theoretically informed exploration of the relation between geographical knowledge and social action; and, finally, in the unprecedented proliferation of research agendas and publications pertaining to these isuuses (Dear 2001: 24. Two recent collections of papers are indicative of the ubiquity of spatial issues in scholarly work.

  10. 32 CFR 636.23 - Turning movements.

    Science.gov (United States)

    2010-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL... movements. (a) U-turns are prohibited on all streets in the cantonment area. (b) Right-turns will be made from a position as close to the right edge or right curb of the roadway as possible. (c) Left-turns...

  11. Realized Beta GARCH

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Lunde, Asger; Voev, Valeri Radkov

    2014-01-01

    as the beta. We apply the model to a large set of assets and find the conditional betas to be far more variable than usually found with rolling-window regressions based exclusively on daily returns. In the empirical part of the paper, we examine the cross-sectional as well as the time variation...... of the conditional beta series during the financial crises....

  12. A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

    DEFF Research Database (Denmark)

    Holst, Birgitte; Nygaard, Rie; Hansen, Louise Valentin

    2010-01-01

    proximity. Mutational analysis was performed in the ghrelin receptor with multiple substitutions and with Ala substitutions in GPR119, GPR39, and the beta(2)-adrenergic receptor as well as the NK1 receptor. In all of these cases, it was found that mutation of the Trp-VI:13 rotameric switch itself eliminated...... could rotate into a position where it obtained an ideal aromatic-aromatic interaction with Phe-V:13. It is concluded that Phe-V:13 can serve as an aromatic lock for the proposed active conformation of the Trp-VI:13 rotameric switch, being involved in the global movement of TM-V and TM-VI in 7TM receptor...

  13. Roughing up Beta

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Li, Sophia Zhengzi; Todorov, Viktor

    -section. An investment strategy that goes long stocks with high jump betas and short stocks with low jump betas produces significant average excess returns. These higher risk premiums for the discontinuous and overnight market betas remain significant after controlling for a long list of other firm characteristics......-section of expected returns. Based on a novel highfrequency dataset of almost one-thousand individual stocks over two decades, we find that the two rough betas associated with intraday discontinuous and overnight returns entail significant risk premiums, while the intraday continuous beta is not priced in the cross...... and explanatory variables previously associated with the cross-section of expected stock returns....

  14. Optimizing magnetic nanoparticles for drinking water technology: The case of Cr(VI)

    Energy Technology Data Exchange (ETDEWEB)

    Simeonidis, K., E-mail: ksime@physics.auth.gr [Department of Mechanical Engineering, School of Engineering, University of Thessaly, Volos 38334 (Greece); Kaprara, E. [Department of Chemical Engineering, Aristotle University of Thessaloniki, Thessaloniki 54124 (Greece); Samaras, T.; Angelakeris, M.; Pliatsikas, N.; Vourlias, G. [Department of Physics, Aristotle University of Thessaloniki, Thessaloniki 54124 (Greece); Mitrakas, M. [Department of Chemical Engineering, Aristotle University of Thessaloniki, Thessaloniki 54124 (Greece); Andritsos, N. [Department of Mechanical Engineering, School of Engineering, University of Thessaly, Volos 38334 (Greece)

    2015-12-01

    The potential of magnetite nanoparticles to be applied in drinking water treatment for the removal of hexavalent chromium is discussed. In this study, a method for their preparation which combines the use of low-cost iron sources (FeSO{sub 4} and Fe{sub 2}(SO{sub 4}){sub 3}) and a continuous flow mode, was developed. The produced magnetite nanoparticles with a size of around 20 nm, appeared relatively stable to passivation providing a removal capacity of 1.8 μg Cr(VI)/mg for a residual concentration of 50 μg/L when tested in natural water at pH 7. Such efficiency is explained by the reducing ability of magnetite which turns Cr(VI) to an insoluble Cr(OH){sub 3} form. The successful operation of a small-scale system consisting of a contact reactor and a magnetic separator demonstrates a way for the practical introduction and recovery of magnetite nanoparticles in water treatment technology. - Highlights: • Iron sulfates were used for the kilogram scale production of Fe{sub 3}O{sub 4} nanoparticles. • Studied particles showed a Cr(VI) removal capacity of 2 μg/mg in natural water. • Cr(VI) uptake is mostly based on its reduction and precipitation as Cr(OH){sub 3}. • A continuous flow reactor–magnetic separator operated with nanoparticles.

  15. Vi overser hjertepatienter med ondt i livet

    DEFF Research Database (Denmark)

    Ørsted-Rasmussen, Morten; Pedersen, Susanne S.; Zwisler, Ann Dorthe Olsen

    2017-01-01

    Sundhedsvæsenet har ved en målrettet indsats sikret markant øget overlevelse efter blodprop i hjertet. Men vi risikerer at skylle det hele ud med badevandet, hvis der ikke bliver taget hånd om de psykiske følger i den kroniske fase af sygdommen......Sundhedsvæsenet har ved en målrettet indsats sikret markant øget overlevelse efter blodprop i hjertet. Men vi risikerer at skylle det hele ud med badevandet, hvis der ikke bliver taget hånd om de psykiske følger i den kroniske fase af sygdommen...

  16. Realistic page-turning of electronic books

    Science.gov (United States)

    Fan, Chaoran; Li, Haisheng; Bai, Yannan

    2014-01-01

    The booming electronic books (e-books), as an extension to the paper book, are popular with readers. Recently, many efforts are put into the realistic page-turning simulation o f e-book to improve its reading experience. This paper presents a new 3D page-turning simulation approach, which employs piecewise time-dependent cylindrical surfaces to describe the turning page and constructs smooth transition method between time-dependent cylinders. The page-turning animation is produced by sequentially mapping the turning page into the cylinders with different radii and positions. Compared to the previous approaches, our method is able to imitate various effects efficiently and obtains more natural animation of turning page.

  17. Comparison of decay and yield data between JNDC2 and ENDF/B-VI

    Energy Technology Data Exchange (ETDEWEB)

    Oyamatsu, K.; Sagosaka, M.; Miyazono, T. [Nagoya Univ. (Japan)

    1997-03-01

    This work is intended to be our first step to solve disagreements of the decay heat powers between measurements and summation calculations. We examine differences between nuclear data libraries to complement our uncertainty evaluation of the decay heat summation calculations only with ENDF/B-VI. The comparison is made mainly between JNDC2 and ENDF/B-VI while JEF2.2 decay data is also discussed. In this study, we propose and use a simple method which is an analogue of the overlap integral of two wave functions in quantum mechanics. As the first step, we compare the whole input nuclear data for the summation calculations as a whole. We find a slight difference of the fission yields especially for high-energy neutron induced fissions between JNDC2 and ENDF/B-VI. As for the decay energies, JNDC2, ENDF/B-VI are quite similar while JEF2.2 is found significantly different from these two libraries. We find substantial differences in the decay constant values among the three libraries. As the second step, we calculate the decay heat powers with FPGS90 using JNDC2 and ENDF/B-VI. The total decay heat powers with the two libraries differ by more than 10% at short cooling times while they agree well on the average at cooling times longer that 100 (s). We also point out nuclides whose contributions are significantly different between the two libraries even though the total decay heats agree well. These nuclides may cause some problems in predicting aggregate spectra of {beta} and {gamma} rays as well as delayed neutrons, and are to be reviewed in the future revision of decay and yield data. (author)

  18. Mechanics of the Fouetté turn.

    Science.gov (United States)

    Imura, Akiko; Yeadon, M R

    2010-12-01

    The Fouetté turn in classical ballet is performed repeatedly on one leg with swinging of the free limbs, producing a continued sequence of turns with one turn leading into the next. The purpose of this study was to determine the possible time history profiles of the twisting torque between the supporting leg and the remainder of the body that will allow continued performances of the Fouetté turn. Simulations were performed using a model which comprised the supporting leg and the remainder of the body to find torque profiles that maintain the initial angular velocity so that the state after one revolution is the same as the initial state. The solution space of torque profiles was determined for various rotation times and coefficients of friction between foot and floor. As the time for one revolution became shorter the solution space became smaller and for a given turn time there was a lower limit on the coefficient of friction. As the frictional coefficient became smaller the solution space became smaller and for a given coefficient there was a lower limit on the turn time. Turns of a given tempo can be performed on floors with different friction by modifying the twisting torque profile. When a turn is completed with a net change in angular velocity this can be compensated for in the next turn by adjusting the twisting torque profile. Copyright © 2010 Elsevier B.V. All rights reserved.

  19. Spectrophotometric study of neptunium (VI) complexation by nitrate ions; Etude par spectrophotometrie de la complexation du neptunium au degre d'oxydation (VI) par les ions nitrates

    Energy Technology Data Exchange (ETDEWEB)

    Pochon, P. [CEA/VALRHO - site de Marcoule, Dept. de Recherche en Retraitement et en Vitrification (DRRV), 30 - Marcoule (France)]|[Conservatoire National des Arts et Metiers (CNAM), 75 - Paris (France)]|[Centre Regional Associe de Lyon, 69 (France)

    2000-07-01

    Neptunium(VI) complexation by nitrate ions was investigated by visible and near-infrared spectrophotometry, a technique suitable for observing the appearance and evolution of the species in solution. In the absence of reference spectra for Np(VI) nitrate- complexes, mathematical (factor analysis) tools were used to interpret the spectra. These chemo-metric techniques were first tested and validated on a simpler chemical system: Np(VI)complexation by the SiW{sub 11}O{sub 39}{sup 8-} anion. The test media used to investigate Np(VI) nitrate- complexes generally contain nitrate and perchlorate salts at high concentrations (high ionic strength). Media effects arising from the presence of cations, acidity or the perchlorate ion concentration are therefore significant, and no doubt account for the scattered values of the complexation constants published in the literature. The evolution of the neptunium spectra according to the parameters of the reaction medium illustrated these effects and allowed them to be quantified by a global 'perturbation constant'. In order to minimize the spectrum modifications due to media effects, the neptunium nitrate-complexes were studied at constant ionic strength in weak acidic media (2 mol.kg{sup -1}{sub H2O}) in the presence of sodium salts. The bulk formation constants and the spectrum of the NpO{sub 2}(NO{sub 3}){sup +} complex were determined for ionic strength values of 2.2, 4, 6 and 8 mol.kg{sup -1}{sub H2O}. The constants remained on the same order of magnitude regardless of the ionic strength; the thermodynamic constant {beta}{sub 1}{sup 0} determined from them according to specific interaction theory is thus probably of little significance. Conversely, the bulk constants can be corrected for the effects of the perchlorate ions by taking the global 'perturbation constant' into account. (author)

  20. Betting Against Beta

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Heje Pedersen, Lasse

    We present a model with leverage and margin constraints that vary across investors and time. We find evidence consistent with each of the model’s five central predictions: (1) Since constrained investors bid up high-beta assets, high beta is associated with low alpha, as we find empirically for U.......S. equities, 20 international equity markets, Treasury bonds, corporate bonds, and futures; (2) A betting-against-beta (BAB) factor, which is long leveraged low beta assets and short high-beta assets, produces significant positive risk-adjusted returns; (3) When funding constraints tighten, the return...... of the BAB factor is low; (4) Increased funding liquidity risk compresses betas toward one; (5) More constrained investors hold riskier assets....

  1. Betting against Beta

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Heje Pedersen, Lasse

    2014-01-01

    We present a model with leverage and margin constraints that vary across investors and time. We find evidence consistent with each of the model's five central predictions: (1) Because constrained investors bid up high-beta assets, high beta is associated with low alpha, as we find empirically...... for US equities, 20 international equity markets, Treasury bonds, corporate bonds, and futures. (2) A betting against beta (BAB) factor, which is long leveraged low-beta assets and short high-beta assets, produces significant positive risk-adjusted returns. (3) When funding constraints tighten......, the return of the BAB factor is low. (4) Increased funding liquidity risk compresses betas toward one. (5) More constrained investors hold riskier assets....

  2. Beta-Ketothiolase Deficiency

    Directory of Open Access Journals (Sweden)

    Elsayed Abdelkreem MD, MSc

    2016-03-01

    Full Text Available Beta-ketothiolase deficiency is an inherited disorder of ketone body metabolism and isoleucine catabolism. It typically manifests as recurrent ketoacidotic episodes with characteristic abnormalities in the urinary organic acid profile. However, several challenges in the diagnosis of beta-ketothiolase deficiency have been encountered: atypical presentations have been reported and some other disorders, such as succinyl-CoA:3-oxoacid CoA transferase and 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiencies, can mimic the clinical and/or biochemical signs of beta-ketothiolase deficiency. A final diagnosis of beta-ketothiolase deficiency requires an enzymatic assay and/or a molecular analysis, but some caveats must be considered. Despite the reported missed cases, screening programs have successfully identified an increasing number of patients with beta-ketothiolase deficiency. Early diagnosis and management of beta-ketothiolase deficiency will enable prevention of its serious acute and chronic complications and ultimately improve the prognosis.

  3. 76 FR 60593 - Title VI; Proposed Circular

    Science.gov (United States)

    2011-09-29

    ... for FTA staff to make oral presentations about the two proposed Circulars and allow attendees an... proposed Circular would incorporate lessons learned from triennial reviews, discretionary Title VI... Implementation Plan for Limited English Proficient (LEP) persons now contains a summary of the DOT LEP guidance...

  4. Prospek pengembangan industri perkulitan pada pelita VI

    OpenAIRE

    D. Karyadi

    1995-01-01

    The leather industry is one of the strong competitive industry, as it comes from renewable natural resources. Therefore, the leather industry has good prospect to develop at the Pelita VI to be the industrial products export competitive. To develop leather industry and leather products should be given closed attention and well managed, especially concerning raw material supply, quality and leather waste treatment.

  5. Resúmenes Presentaciones Orales VI ECAP

    OpenAIRE

    Vargas Arana, Editor Gabriel

    2016-01-01

    En este artículo se pueden encontrar los resúmenes de las presentaciones orales del VI Ecuentro Científico de la Amazonía Peruana, desarrollado el 27 y 28 de cotubre de 2015 en la ciudad de Iquitos, Perú.

  6. Vi har selv designet naturens love

    DEFF Research Database (Denmark)

    Bentzen, Martin Mose

    2014-01-01

    ForskerZonenNaturlovene er universelt gyldige i de flestes øjne. De gælder altid, uanset hvad vi tænker. Men dette billede står ikke uimodsagt i videnskabsfilosofien, og der er meget, der tyder på, at det ikke er specielt empirisk korrekt...

  7. Chromium(VI) bioremediation by probiotics.

    Science.gov (United States)

    Younan, Soraia; Sakita, Gabriel Z; Albuquerque, Talita R; Keller, Rogéria; Bremer-Neto, Hermann

    2016-09-01

    Chromium is a common mineral in the earth's crust and can be released into the environment from anthropogenic sources. Intake of hexavalent chromium (Cr(VI)) through drinking water and food causes toxic effects, leading to serious diseases, and is a commonly reported environmental problem. Microorganisms can mitigate or prevent the toxic effects caused by heavy metals in addition to having effective resistance mechanisms to prevent cell damage and bind to these metals, sequestering them from the cell surface and removing them from the body. Species of Lactobacillus, Streptococcus, Bacillus and Bifidobacterium present in the human mouth and gut and in fermented foods have the ability to bind and detoxify some of these substances. This review address the primary topics related to Cr(VI) poisoning in animals and humans and the use of probiotics as a way to mitigate or prevent the toxic effects caused by Cr(VI). Further advances in the genetic knowledge of such microorganisms may lead to discoveries which will clarify the most active microorganisms that act as bioprotectants in bodies exposed to Cr(VI) and are an affordable option for people and animals intoxicated by the oral route. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  8. 77 FR 52116 - Title VI; Final Circular

    Science.gov (United States)

    2012-08-28

    ... enforcement of Title VI disparate impact regulations, it did not undermine the validity of those regulations... streamlined this process. We have modified the definition of ``disparate impact'' for clarity. We decline to... process reengineering. In response, FTA will review the public engagement plan and its implementation when...

  9. Hvem er vi? Hvem er de?

    DEFF Research Database (Denmark)

    Kryger, Niels

    2016-01-01

    Kommentaren tager afsæt i initiativer i de pædagogiske faglige foreninger i Europa EERA) og i Norden (NERA) og argumenterer for at det er forpligtelse for os som nordiske og europæiske pædagogiske forskere at gå op imod de stadigt mere ekskluderende vi-konstruktioner, som er blevet formuleret i for...

  10. Do benzodiazepines mimic reverse-turn structures?

    Science.gov (United States)

    Hata, Masayuki; Marshall, Garland R.

    2006-05-01

    The role of benzodiazepine derivatives (BZD) as a privileged scaffold that mimics β-turn structures (Ripka et al. (1993) Tetrahedron 49:3593-3608) in peptide/protein recognition was reexamined in detail. Stable BZD ring conformers were determined with MM3, and experimental reverse-turn structures were extracted from the basis set of protein crystal structures previously defined by Ripka et al. Ideal β-turns were also modeled and similarly compared with BZD conformers. Huge numbers of conformers were generated by systematically scanning the torsional degrees of freedom for BZDs, as well as those of ideal β-turns for comparison. Using these structures, conformers of BZDs were fit to experimental structures as suggested by Ripka et al., or modeled classical β-turn conformers, and the root-mean-square deviation (RMSD) values were calculated for each pairwise comparison. Pairs of conformers with the smallest RMSD values for overlap of the four α-β side-chain orientations were selected. All overlaps of BZD conformers with experimental β-turns yielded one or more comparisons where the least RMSD was significantly small, 0.48-0.86 Å, as previously suggested. Utilizing a different methodology, the overall conclusion that benzodiazepines could serve as reverse-turn mimetics of Ripka et al. is justified. The least RMSD values for the overlap of BZDs and modeled classical β-turns were also less than 1 Å. When comparing BZDs with experimental or classical β-turns, the set of experimental β-turns selected by Ripka et al. fit the BZD scaffolds better than modeled classical β-turns; however, all the experimental β-turns did not fit a particular BZD scaffold better. A single BZD ring conformation, and/or chiral orientation, can mimic some, but not all, of the experimental β-turn structures. BZD has two central ring conformations and one chiral center that explains why the four variations of the BZD scaffold can mimic all types of β-turn structure examined. It was

  11. performance characteristics of a cam turning attachment

    African Journals Online (AJOL)

    Dr Obe

    ABSTRACT. A modification of a cylindrical turning unit has been done to give a non- cylindrical turning attachment for production of irregular shapes, like cams on the lathe machine. To assess the performance of the attachment, cutting forces have been measured using a 'Sigma' Cutting Tool. Dynamometer. Furthermore ...

  12. Kantian Turning Point in Gadamer's Philosophical Hermeneutics

    Directory of Open Access Journals (Sweden)

    Kristína Bosáková

    2016-11-01

    Full Text Available The paper is treating the theme of a Kantian turning-point in the philosophical hermeneutics of H.- G. Gadamer based on of the harmonic relationship between metaphysics and science in Kantian philosophy from the point of view of the philosophical hermeneutics of Gadamer. The philosophical work of Kant had such an influence on Gadamer that without exaggerating we can talk about the Kantian turning-point in Gadamerian hermeneutics. Grondin, a former student of Gadamer, is talking about Kantian turning-point on the field of aesthetics, but in reality Kantian turning-point means much more than a mere change in the reception of the concept of judgement. It is a discovery of harmonical relationship between the beauty and the moral, between the reason and the sensitivity, between the modern sciences and the metaphysical tradition in the Kantian philosophy, made by Gadamer. This is what we call the Kantian turning-point in Gadamerian hermeneutics.

  13. Cloning and expression of a Vi mimotope of Salmonella enterica ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... A recombinant His-Vi protein of Salmonella enterica serovar Typhi was successfully constructed and cloned into an expression vector ... recombinant protein can be used to detect specific anti-Vi antibody produced by typhoid patients. Overall, the His-Vi ... E-mail: khchua@um.edu.my. Tel.:603-. 79676607.

  14. Bioreduction of Cr (VI) by potent novel chromate resistant alkaliphilic ...

    African Journals Online (AJOL)

    Isolation of Cr (VI) resistant alkaliphilic bacteria from sediment and water samples collected from Wadi Natrun hypersaline Soda lakes (located in northern Egypt), resulted in isolation of several alkaliphilic bacterial strains that can tolerate up to 2.94 g/l of Cr (VI) in alkaline medium. However, with increasing Cr (VI) ...

  15. Beta-Carotene

    Science.gov (United States)

    ... to long-term liver disease, a disease called amyotrophic lateral sclerosis (ALS), and the enlargement of a blood vessel ... of beta-carotene daily doesnt have any benefit. Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease). Taking beta-carotene supplements ...

  16. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    2012-10-06

    Oct 6, 2012 ... The physics potential of neutrinoless double beta decay is discussed. Furthermore, experimental considerations as well as the current status of experiments are presented. Finally, an outlook towards the future, work on nuclear matrix elements and alternative processes is given. Keywords. Double beta ...

  17. 14 CFR 23.203 - Turning flight and accelerated turning stalls.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Turning flight and accelerated turning stalls. 23.203 Section 23.203 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... a 30 degree bank. Reduce speed by steadily and progressively tightening the turn with the elevator...

  18. Beta Regression Finite Mixture Models of Polarization and Priming

    Science.gov (United States)

    Smithson, Michael; Merkle, Edgar C.; Verkuilen, Jay

    2011-01-01

    This paper describes the application of finite-mixture general linear models based on the beta distribution to modeling response styles, polarization, anchoring, and priming effects in probability judgments. These models, in turn, enhance our capacity for explicitly testing models and theories regarding the aforementioned phenomena. The mixture…

  19. Rapid synthesis of beta zeolites

    Science.gov (United States)

    Fan, Wei; Chang, Chun -Chih; Dornath, Paul; Wang, Zhuopeng

    2015-08-18

    The invention provides methods for rapidly synthesizing heteroatom containing zeolites including Sn-Beta, Si-Beta, Ti-Beta, Zr-Beta and Fe-Beta. The methods for synthesizing heteroatom zeolites include using well-crystalline zeolite crystals as seeds and using a fluoride-free, caustic medium in a seeded dry-gel conversion method. The Beta zeolite catalysts made by the methods of the invention catalyze both isomerization and dehydration reactions.

  20. Noget vi kan tro på

    DEFF Research Database (Denmark)

    Olsen, Jan Brødslev

    2016-01-01

    Situationen er alvorlig. Verden står over for enorme udfordringer med pres på naturressourcer, klima, befolkningsvækst, flygtninge og konflikter. Det er svært at se, hvordan disse problemer kan håndteres inden for den nuværende menneskelige bevidstheds rammer. Vi må derfor foretage et bevidstheds......Situationen er alvorlig. Verden står over for enorme udfordringer med pres på naturressourcer, klima, befolkningsvækst, flygtninge og konflikter. Det er svært at se, hvordan disse problemer kan håndteres inden for den nuværende menneskelige bevidstheds rammer. Vi må derfor foretage et...

  1. Hvad skal vi med Trump-satire?

    DEFF Research Database (Denmark)

    Møller, Mette

    2017-01-01

    Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?......Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?...

  2. CPE OF URANIUM (VI USING IONIC LIQUID

    Directory of Open Access Journals (Sweden)

    SANAA NAÏT-TAHAR

    2016-07-01

    Full Text Available Cloud point extraction (CPE was used to extract uranium (VI from an aqueous solution in acetate media. The methodology used is based on the formation of uranyl-ionic liquid (I complexes and uranyl-D2EHPA soluble in a micellar phase of non-ionic surfactant (Triton X-100. The uranium (VI complexes are then extracted into the surfactant-rich phase at ambient temperature. The ionic liquid (IL used as a chelating agent was synthesized and characterized in this study. It is composed of N-butyl N’-triethoxy methyl imidazolium cation and diethylhexylphosphate (D2EHPA-H as anion. The effect of the IL on the extraction efficiency was studied in presence and in absence of IL’s cation in acetate medium.

  3. Next Speakers Plan Their Turn Early and Speak after Turn-Final "Go-Signals".

    Science.gov (United States)

    Barthel, Mathias; Meyer, Antje S; Levinson, Stephen C

    2017-01-01

    In conversation, turn-taking is usually fluid, with next speakers taking their turn right after the end of the previous turn. Most, but not all, previous studies show that next speakers start to plan their turn early, if possible already during the incoming turn. The present study makes use of the list-completion paradigm (Barthel et al., 2016), analyzing speech onset latencies and eye-movements of participants in a task-oriented dialogue with a confederate. The measures are used to disentangle the contributions to the timing of turn-taking of early planning of content on the one hand and initiation of articulation as a reaction to the upcoming turn-end on the other hand. Participants named objects visible on their computer screen in response to utterances that did, or did not, contain lexical and prosodic cues to the end of the incoming turn. In the presence of an early lexical cue, participants showed earlier gaze shifts toward the target objects and responded faster than in its absence, whereas the presence of a late intonational cue only led to faster response times and did not affect the timing of participants' eye movements. The results show that with a combination of eye-movement and turn-transition time measures it is possible to tease apart the effects of early planning and response initiation on turn timing. They are consistent with models of turn-taking that assume that next speakers (a) start planning their response as soon as the incoming turn's message can be understood and (b) monitor the incoming turn for cues to turn-completion so as to initiate their response when turn-transition becomes relevant.

  4. Corneal hysteresis in mucopolysaccharidosis I and VI.

    Science.gov (United States)

    Fahnehjelm, Kristina Teär; Chen, Enping; Winiarski, Jacek

    2012-08-01

    High intraocular pressure (IOP) and glaucoma are often suspected in patients with mucopolysaccharidosis (MPS). To determine corneal hysteresis (CH) and IOP in children with mucopolysaccharidosis I-Hurler (MPS I-H) and MPS VI. Clinical measurements with ocular response analyzer (ORA). In seven patients, five with MPS I-H treated with stem cell transplantation (SCT), and two with MPS VI, one treated with SCT and the other with enzyme therapy, the IOP was examined with ORA. Ocular response analyzer measurements were made at a median age of 8.7 years in the patients with MPS I-H and at a median age of 9.3 years in the patients with MPS VI. Earlier measurements had raised suspicion of high IOP in one patient. The ORA showed an increased CH and a falsely high IOP values in all 14 eyes. The recalculated IOPs were normal in all 14 eyes. Mild to severe corneal opacities were present in all 14 eyes. Optic disc areas, borders and cupping were clinically normal in the 12 of 14 eyes that were possible to examine. Severe corneal opacities hampered optic disc evaluation in the older patient with MPS VI. Three eyes in two patients had normal thickness of the retinal nerve fibre layer measured with scanning laser polarimetry with corneal compensation (GDx VCC). No patient was diagnosed or treated for glaucoma. The IOPs are often falsely high because of an increased resistance of the cornea and correlate to the extent of corneal clouding. In this small, cross-sectional study, it appears that corneal resistance is directly correlated with corneal clouding, although a longitudinal study that evaluates resistance as the cornea clears with treatment would provide more direct evidence that corneal deposits are directly related to resistance. A correct measured IOP can avoid unnecessary medical or surgical hypotensive treatment. © 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.

  5. Prospek pengembangan industri perkulitan pada pelita VI

    Directory of Open Access Journals (Sweden)

    D Karyadi

    1995-06-01

    Full Text Available The leather industry is one of the strong competitive industry, as it comes from renewable natural resources. Therefore, the leather industry has good prospect to develop at the Pelita VI to be the industrial products export competitive. To develop leather industry and leather products should be given closed attention and well managed, especially concerning raw material supply, quality and leather waste treatment.

  6. Cellular Reprogramming–Turning the Clock Back

    Indian Academy of Sciences (India)

    Cellular Reprogramming - Turning the Clock Back - Nobel Prize in Physiology or Medicine, 2012. Deepa Subramanyam ... Keywords. Embryonic stem cells; pluripotency; reprogramming; differentiation; Nobel Prize 2012. ... National Centre for Cell Science University of Pune Campus Ganeshkhind Pune 411 007, India.

  7. Page turning solutions for musicians: a survey.

    Science.gov (United States)

    Wolberg, George; Schipper, Irene

    2012-01-01

    Musicians have long been hampered by the challenge in turning sheet music while their hands are occupied playing an instrument. The sight of a human page turner assisting a pianist during a performance, for instance, is not uncommon. This need for a page turning solution is no less acute during practice sessions, which account for the vast majority of playing time. Despite widespread appreciation of the problem, there have been virtually no robust and affordable products to assist the musician. Recent progress in assistive technology and electronic reading devices offers promising solutions to this long-standing problem. The objective of this paper is to survey the technology landscape and assess the benefits and drawbacks of page turning solutions for musicians. A full range of mechanical and digital page turning products are reviewed.

  8. Derrida’s Turn to Franciscan Philosophy

    Directory of Open Access Journals (Sweden)

    Marko Zlomislic

    2008-12-01

    Full Text Available Contemporary French philosophers such as Levinas, Bataille, and Derrida, along with the existentialists Kierkegaard and Nietzsche have all made use of Franciscan insights in order to safeguard the ipseity that cannot be reduced or totalized. In keeping with the taste that concerns me, this paper will examine Derrida’s turn to the poetry of Gerard Manley Hopkins and how such a turn may place Derrida within a catholic and Franciscan tradition.

  9. Turning Down the Noise in the Blogosphere

    Science.gov (United States)

    2009-05-01

    Fearless Kitchen: Recipe: Medieval Lamb Wrap 5. How Obama avoided a misguided policy blunder A post describing the Oscar-nominated movie The Curious Case...prevalent stories and many entertaining or shocking posts, such as “ Teen Stabbed But Makes It To Job Interview,” the top post from February 6. TDN...origin, sex or handicap in violation of Title VI of the Civil Rights Act of 1964, Title IX of the Educational Amendments of 1972 and Section 504 of the

  10. Mucopolissacaridose tipo VI: relato de caso

    Directory of Open Access Journals (Sweden)

    Lais Orosco Bialon Santana

    2014-10-01

    Full Text Available Introdução: As mucopolissacaridoses são erros inatos do metabolismo de depósito lisossomal subclassificadas segundo a enzima deficiente. A arilsulfatase B (ARSB, responsável por degradar os glicosaminoglicanos (GAGs, que atuam no tecido conjuntivo, é deficiente na mucopolissacaridose tipo VI (MP VI. A MP VI tem clínica variável, sem anormalidades ao nascimento, evidenciando-se progressivamente ao acúmulo de GAGs. O diagnóstico se faz pela redução da atividade da ARSB ou da mutação genética. A principal causa de óbito é insuficiência cardíaca, ocorrendo na segunda ou terceira década de vida. Relato de Caso: Masculino, 4 anos, portador de MP VI, há 3 dias com febre e sinais flogísticos em sítio de acesso central, colocado para reposição enzimática, com flutuação e saída de material purulento. Ultrassom evidenciou coleção laminar e borramento de planos gordurosos. Ecocardiograma demonstra hipertensão pulmonar discreta decorrente de prolapso valvar mitral com refluxo discreto, além de endocardite da valva mitral. Optou-se por retirada cirúrgica do dispositivo e administração de vancomicina e amicacina. Durante internação, evoluiu bem, sem complicações pós operatórias. Conclusão: A MP VI têm inteligência preservada, baixa estatura e alterações osteomusculares, como no caso relatado. Não há correlação entre a gravidade clínica e a atividade residual enzimática. Dificuldade respiratória pode levar a hipóxia crônica, hipertensão pulmonar e insuficiência cardíaca congestiva. Das alterações cardíacas, encontramos valvulopatias, insuficiência cardíaca e hipertensão pulmonar, observadas no caso. O tratamento se faz com transplante de células-tronco hematopoiéticas e terapia de reposição enzimática.

  11. Beta Thalassemia (For Parents)

    Science.gov (United States)

    ... anemia or failure to thrive. If the doctor suspects beta thalassemia, he or she will take a ... test called a hemoglobin electrophoresis and/or a DNA test for abnormal hemoglobin genes. If both parents ...

  12. An Overview on Production and Applications of Ferrate(VI

    Directory of Open Access Journals (Sweden)

    Talaiekhozani

    2016-03-01

    Full Text Available Context Coagulation, chemical oxidation and disinfection are essential processes in water and waste treatment. A chemical that can be applied for all the above mentioned purposes is ferrate(VI. Although there are many studies about ferrate(VI, no comprehensive review paper can be found about ferrate(VI from production to applications. The aim of this study was to review ferrate(VI production, measurement, stability and utilization in water and wastewater treatment. Evidence Acquisition In acidic conditions, the oxidation and reduction capacity of ferrate(VI is superior to all currently utilized oxidizers and disinfectants in water and wastewater treatment. New researches have provided the technology of using ferrate(VI for coagulation, chemical oxidation and disinfection of water and wastewater in a reactor simultaneously, which can reduce the size of water and wastewater treatment plants and increase the treatment efficiency. Results Despite the existence of these technologies, there is no full-scale application of ferrate(VI in the water and wastewater industry which it is due to difficulties associated with I, the lack of adequate researches that have demonstrated its capabilities and advantages over the existing water and wastewater treatment methods; ii, the instability of ferrate(VI depending on its method of preparation, and iii, the relatively low yield of ferrate(VI. Conclusions To solve the above mentioned difficulties, fundamental study most be carried out to discover the novel methods of ferrate(VI production, focusing on increasing the product stability and the production yield.

  13. High beta multipoles

    Energy Technology Data Exchange (ETDEWEB)

    Prager, S C

    1982-05-01

    Multipoles are being employed as devices to study fusion issues and plasma phenomena at high values of beta (plasma pressure/magnetic pressure) in a controlled manner. Due to their large volume, low magnetic field (low synchrotron radiation) region, they are also under consideration as potential steady state advanced fuel (low neutron yield) reactors. Present experiments are investigating neoclassical (bootstrap and Pfirsch-Schlueter) currents and plasma stability at extremely high beta.

  14. Beta-thalassemia

    OpenAIRE

    Origa Raffaella; Galanello Renzo

    2010-01-01

    Abstract Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main forms have been described: thalassemia major, thalassemia intermedia and thalassemia minor...

  15. {beta} - amyloid imaging probes

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Jae Min [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2007-04-15

    Imaging distribution of {beta} - amyloid plaques in Alzheimer's disease is very important for early and accurate diagnosis. Early trial of the {beta} -amyloid plaques includes using radiolabeled peptides which can be only applied for peripheral {beta} - amyloid plaques due to limited penetration through the blood brain barrier (BBB). Congo red or Chrysamine G derivatives were labeled with Tc-99m for imaging {beta} - amyloid plaques of Alzheimer patient's brain without success due to problem with BBB penetration. Thioflavin T derivatives gave breakthrough for {beta} - amyloid imaging in vivo, and a benzothiazole derivative [C-11]6-OH-BTA-1 brought a great success. Many other benzothiazole, benzoxazole, benzofuran, imidazopyridine, and styrylbenzene derivatives have been labeled with F-18 and I-123 to improve the imaging quality. However, [C-11]6-OH-BTA-1 still remains as the best. However, short half-life of C-11 is a limitation of wide distribution of this agent. So, it is still required to develop an Tc-99m, F-18 or I-123 labeled agent for {beta} - amyloid imaging agent.

  16. Bodily-visual practices and turn continuation.

    Science.gov (United States)

    Ford, Cecilia E; Thompson, Sandra A; Drake, Veronika

    2012-01-01

    This paper considers points in turn construction where conversation researchers have shown that talk routinely continues beyond possible turn completion, but where we find bodily-visual behavior doing such turn extension work. The bodily-visual behaviors we examine share many features with verbal turn extensions, but we argue that embodied movements have distinct properties that make them well-suited for specific kinds of social action, including stance display and by-play in sequences framed as subsidiary to a simultaneous and related verbal exchange. Our study is in line with a research agenda taking seriously the point made by Goodwin (2000a, b, 2003), Hayashi (2003, 2005), Iwasaki (2009), and others that scholars seeking to account for practices in language and social interaction do themselves a disservice if they privilege the verbal dimension; rather, as suggested in Stivers/Sidnell (2005), each semiotic system/modality, while coordinated with others, has its own organization. With the current exploration of bodily-visual turn extensions, we hope to contribute to a growing understanding of how these different modes of organization are managed concurrently and in concert by interactants in carrying out their everyday social actions.

  17. The role of estrogen receptor {beta} (ER{beta}) in malignant diseases-A new potential target for antiproliferative drugs in prevention and treatment of cancer

    Energy Technology Data Exchange (ETDEWEB)

    Warner, Margaret [Center for BioSciences, Department of BioSciences and Nutrition, Karolinska Institutet, Stockholm (Sweden); Center for Nuclear Receptors and Cell Signaling, Department of Biochemistry and Cell Biology, University of Houston, Houston, TX (United States); Gustafsson, Jan-Ake, E-mail: jan-ake.gustafsson@mednut.ki.se [Center for BioSciences, Department of BioSciences and Nutrition, Karolinska Institutet, Stockholm (Sweden); Center for Nuclear Receptors and Cell Signaling, Department of Biochemistry and Cell Biology, University of Houston, Houston, TX (United States)

    2010-05-21

    The discovery of ER{beta} in the middle of the 1990s represents a paradigm shift in our understanding of estrogen signaling. It has turned out that estrogen action is not mediated by one receptor, ER{alpha}, but by two balancing factors, ER{alpha} and ER{beta}, which are often antagonistic to one another. Excitingly, ER{beta} has been shown to be widespread in the body and to be involved in a multitude of physiological and pathophysiological events. This has led to a strong interest of the pharmaceutical industry to target ER{beta} by drugs against various diseases. In this review, focus is on the role of ER{beta} in malignant diseases where the anti proliferative activity of ER{beta} gives hope of new therapeutic approaches.

  18. Turning points in the history of mathematics

    CERN Document Server

    Grant, Hardy

    2015-01-01

    This book explores some of the major turning points in the history of mathematics, ranging from ancient Greece to the present, demonstrating the drama that has often been a part of its evolution. Studying these breakthroughs, transitions, and revolutions, their stumbling-blocks and their triumphs, can help illuminate the importance of the history of mathematics for its teaching, learning, and appreciation. Some of the turning points considered are the rise of the axiomatic method (most famously in Euclid), and the subsequent major changes in it (for example, by David Hilbert); the “wedding,” via analytic geometry, of algebra and geometry; the “taming” of the infinitely small and the infinitely large; the passages from algebra to algebras, from geometry to geometries, and from arithmetic to arithmetics; and the revolutions in the late nineteenth and early twentieth centuries that resulted from Georg Cantor’s creation of transfinite set theory. The origin of each turning point is discussed, along with...

  19. Market turning points forecasting using wavelet analysis

    Science.gov (United States)

    Bai, Limiao; Yan, Sen; Zheng, Xiaolian; Chen, Ben M.

    2015-11-01

    Based on the system adaptation framework we previously proposed, a frequency domain based model is developed in this paper to forecast the major turning points of stock markets. This system adaptation framework has its internal model and adaptive filter to capture the slow and fast dynamics of the market, respectively. The residue of the internal model is found to contain rich information about the market cycles. In order to extract and restore its informative frequency components, we use wavelet multi-resolution analysis with time-varying parameters to decompose this internal residue. An empirical index is then proposed based on the recovered signals to forecast the market turning points. This index is successfully applied to US, UK and China markets, where all major turning points are well forecasted.

  20. CONNECTION OF TURN AHEAD AND TURN BACK WITH MOTORIC ABILITIES OF THE FIFTH GRADE STUDENTS

    Directory of Open Access Journals (Sweden)

    Jovica Petković

    2006-06-01

    Full Text Available The research is done for the purpose of determination and defining of the level of connection between some motoric abilities with success in realization of programmed contents from the area of gymnastics (turn ahead and turn back. The research is done on the sample of fifty one students from the fifth grade of Elementary School, on ten motoric tests and on two specific motoric assignments – turn ahead and turn back. The results of this research clearly point that there exist the multitude of statistically important coefficients of correlation between treated motoric abilities and applied motoric assignments.

  1. Farvel til globaliseringen som vi kendte den

    DEFF Research Database (Denmark)

    Böss, Michael

    2009-01-01

    Vi er endt med en krise, som rækker langt ud over det globale monetære system, fordi den ideologiske ortodoksi, der skabte den, har ført til udflytning af millioner af arbejdspladser, tæring af nationalstaternes sammenhængskraft og overgreb på naturen. Kronikken refererer bl.a. til John Maynard...... Keynes og en artikel af økonomen Robert Skidelsky i The American Prospect. Udgivelsesdato: 12. januar 2009...

  2. "LICENS ER NOGET VI GIVER TIL HINANDEN"

    OpenAIRE

    Svendsen, Nana Lysbo; Birksholm, Sarah Schlander; Rosendahl, Rasmus; Albrechtsen, Nadja Loran

    2013-01-01

    This study consists of a rhetorical analysis of how the Danish Broadcasting Corporation argues for the compulsory license fee in their campaign video: ’Licens er noget vi giver til hinanden’. On the assumption that a visual product can argue on equal terms with the spoken language, the paper will look at the specific visual tools that are used in the argumentation and the portrayal of the concept of public service and the license fee. In extension to this the paper will examine if the vid...

  3. Oral–Facial–Digital Syndrome type VI with self mutilations

    Directory of Open Access Journals (Sweden)

    Rabah M. Shawky

    2014-10-01

    Full Text Available We report the case of a 2.5 year old female, 2nd in order of birth of 1st cousin consanguineous marriage, with the typical features of Oral–Facial–Digital Syndrome type VI (OFDS VI including midline pseudo cleft upper lip, sublingual nodule, molar tooth sign by MRI brain, bilateral mesoaxial polydactyly (hexadactyly, and developmental delay. The patient had self mutilations which was not reported before in OFDS VI except once.

  4. Environmental survey of Region VI, Haltenbanken, 2009; Miljoeundersoekelse i Region VI, Haltenbanken, 2009

    Energy Technology Data Exchange (ETDEWEB)

    Holm, May-Helen; Cochrane, Sabine; Mannvik, Hans-Petter; Wasbotten, Ingar Halvorsen

    2010-07-01

    There has been an environmental investigation in Region VI Halten Bank. This report presents the results of the chemical and biological assays performed on samples from a total of 316 stations in 16 fields and 15 regional stations. A status of environmental conditions in the region is given at the end of the report. (AG)

  5. Environmental Survey in Region VI, Haltenbanken, 2009. Summary report; Miljoeundersoekelse i Region VI, Haltenbanken, 2009. Sammendragsrapport

    Energy Technology Data Exchange (ETDEWEB)

    Mannvik, Hans-Petter; Wasbotten, Ingar Halvorsen

    2010-07-01

    An environmental survey of Region VI, Haltenbanken, has been carried out. This report presents the results from the analyses carried out on samples from a total of 316 stations at 16 fields and 15 regional stations. A status of the environmental conditions in the region is given at the end of the report. (Author)

  6. Fremtidens lavenergibyggeri - kan vi gøre som vi plejer?

    DEFF Research Database (Denmark)

    Larsen, Tine Steen

    2011-01-01

    Stramninger af kravene til energiforbruget i vores boliger medfører stor fokus på energiberegningen, men erfaringer fra lavenergiboliger opført i dag viser, at vi, for at sikre succes for fremtidens boliger, også skal inddrage dokumentation af indeklimaet og forbedre samarbejdet mellem arkitekter...

  7. Vi lider af prætraumatisk stress

    DEFF Research Database (Denmark)

    Hansen, Brian Benjamin

    2009-01-01

    Vi lider af prætraumatisk stress. Vi vil nemlig nå det hele og presser konstant nye aftaler ind i vores kalender. Det eneste, der hjælper, er at ’gøre intet’ – men kan man overhovedet det? Udgivelsesdato: 30.09.09......Vi lider af prætraumatisk stress. Vi vil nemlig nå det hele og presser konstant nye aftaler ind i vores kalender. Det eneste, der hjælper, er at ’gøre intet’ – men kan man overhovedet det? Udgivelsesdato: 30.09.09...

  8. Behaviour of chromium(VI) in stormwater soil infiltration systems

    DEFF Research Database (Denmark)

    Cederkvist, Karin; Ingvertsen, Simon T.; Jensen, Marina B.

    2013-01-01

    The ability of stormwater infiltration systems to retain Cr(VI) was tested by applying a synthetic stormwater runoff solution with a neutral pH and high Cr(VI) concentrations to four intact soil columns excavated from two roadside infiltration swales in Germany. Inlet flow rates mimicked normal (10......, while under extreme rain events approximately 20% of Cr(VI) was retained. In both cases effluent concentrations of Cr(VI) would exceed the threshold value of 3.4 mu g/L if the infiltrated water were introduced to freshwater environments. More knowledge on the composition of the stormwater runoff...

  9. Remediation of Cr(VI) in solution using vitamin C*

    OpenAIRE

    LIU, Yong; Xu, Xin-hua; He, Ping

    2005-01-01

    The effectiveness of vitamin C in treating Cr(VI)-contaminated water is being evaluated. Cr(VI) is an identified pollutant of some soils and groundwater. Vitamin C, an important biological reductant in humans and animals, can be used to transform Cr(VI) to essentially nontoxic Cr(III). The removal efficiency was 89% when the mass concentration of vitamin C was 80 mg/L in 60 min, and nearly 100% Cr(VI) was removed when the mass concentration was 100 mg/L. Our data demonstrated that the removal...

  10. Heterogeneity of collagens in rabbit cornea: type VI collagen

    National Research Council Canada - National Science Library

    Cintron, C; Hong, BS

    1988-01-01

    .... These physical characteristics, together with the susceptibility of these polypeptides to collagenase and their amino acid composition, identified the high molecular weight aggregate as type VI collagen...

  11. The dynamic turn in quantum logic

    NARCIS (Netherlands)

    Baltag, Alexandru; Smets, Sonja

    In this paper we show how ideas coming from two areas of research in logic can reinforce each other. The first such line of inquiry concerns the "dynamic turn" in logic and especially the formalisms inspired by Propositional Dynamic Logic (PDL); while the second line concerns research into the

  12. Leadership Helps Turn around a Troubled School

    Science.gov (United States)

    Sheppard, Von

    2013-01-01

    The author tells how he employed leadership skills to help turn around a failing school loaded with at-risk students. Dayton's Bluff Elementary School was one of the worst in St. Paul when Von Sheppard took over as principal in 2001. Changing the staff and attitudes at the largely low-income, minority majority school in a tough neighborhood helped…

  13. Train turn restrictions and line plan performance

    DEFF Research Database (Denmark)

    Burggraeve, Sofie; Bull, Simon Henry; Lusby, Richard Martin

    In this paper we study the impact of the `turn conditions' in end stations on the performance of a line plan. If trains have to turn on their platform in an end station, the yoccupy the platform for several minutes. A more preferred option, from a timetabling point of view, would be that a train...... disappears from the platform in its end station after dwelling and only appears again when departing for a subsequent trip. In this case, the train will not interfere with other trains that dwell on the platform during the time between these events. However, this option is only possible if the train can stay...... in a exible and large enough shunt. Starting from a given line plan, we compare two timetables, one where trains have to turn on their platform and one where trains can turn in a shunt. We evaluate the impact on the performance of the line plan by its feasibility for timetabling,the minimum overall buffer...

  14. Face to Face Turning A New Leaf

    Indian Academy of Sciences (India)

    Face to Face. Thissectionfeaturesconversationswithpersonalitiesrelated to science, highlighting the factors and circumstances that guided them in making the career choice to be a scientist. Turning A New Leaf. H Y Mohan Ram talks to Sujata Varadarajan. Prof. H Y Mohan Ram is a man of myriad interests and talents and is ...

  15. Strategy in Generative Planning of Turning Processes

    NARCIS (Netherlands)

    van Houten, Frederikus J.A.M.; Kals, H.J.J.

    1986-01-01

    This paper reports on the process and operations planning system ROUND and the strategies which underlie the decision making processes in the planning of turning operations. At first, an outline is given about the environment for which generative systems like ROUND are being developed. The

  16. Business Intelligence: Turning Knowledge into Power

    Science.gov (United States)

    Endsley, Krista

    2009-01-01

    Today, many school districts are turning to business intelligence tools to retrieve, organize, and share knowledge for faster analysis and more effective, guided decision making. Business intelligence (BI) tools are the technologies and applications that gather and report information to help an organization's leaders make better decisions. BI…

  17. The experience turn as ‘bandwagon’

    DEFF Research Database (Denmark)

    Fuglsang, Lars; Eide, Dorthe

    2013-01-01

    This paper uses the bandwagon metaphor to analyse, in two rural contexts, how small tourism firms become engaged in the idea of the experience economy and how the idea is turned into practice through network formation and innovation. In developing a practice-based approach we use the bandwagon...

  18. Beta-blocker Therapy and Clinical Outcomes in Patients with Moderate COPD and Heightened Cardiovascular Risk: An Observational Sub-study of SUMMIT.

    Science.gov (United States)

    Dransfield, Mark T; McAllister, David A; Anderson, Julie A; Brook, Robert D; Calverley, Peter M A; Celli, Bartolome R; Crim, Courtney; Gallot, Natacha; Martinez, Fernando J; Scanlon, Paul D; Yates, Julie; Vestbo, Jørgen; Newby, David E

    2018-02-06

    Cardiovascular disease is a common comorbidity in patients with chronic obstructive pulmonary disease (COPD). Although beta-blockers can be used safely in COPD, concerns remain regarding safety and efficacy interactions in patients using concomitant inhaled long-acting beta-agonists. To compare the differential effects of long-acting beta agonist or inhaled corticosteroid use on clinical outcomes in patients with heightened cardiovascular risk treated and not treated with beta-blockers. We examined data from 16,485 participants in the Study to Understand Mortality and MorbidITy in COPD (SUMMIT) who were randomized to once daily inhaled fluticasone furoate (FF), vilanterol (VI), their combination (FF/VI), or placebo and examined the associations between treatment allocation and lung function, COPD exacerbations, cardiovascular events, and all-cause mortality stratified by baseline beta-blocker therapy. Baseline beta-blocker therapy was used by 31% (n=5,159) of SUMMIT participants. There was no evidence of an interaction between baseline beta-blocker therapy and the association between inhaled treatments and FEV1 at 3 months (p=0.27), 6 months (p=0.14), or 12 months (p=0.33). The placebo-adjusted mean difference in post-bronchodilator FEV1 at 3 months in the VI alone group was 58 mL [95% confidence interval (CI) 38, 78] in those taking baseline beta-blocker therapy, and 51 mL [95%CI 38, 65], in those not taking baseline beta-blocker therapy. The placebo-adjusted mean difference in post-bronchodilator FEV1 at 3 months in the FF/VI group was 85 mL [95%CI 65, 105] in those taking baseline beta-blocker therapy, and 68 mL [95%CI 54, 82] in those not taking baseline beta-blocker therapy. Overall, there was no evidence of interactions by randomized treatment, including VI alone or in combination with FF, for COPD exacerbations (p=0.18), cardiovascular composite events (p=0.33), and all-cause mortality (p=0.41). There is no evidence to suggest that baseline beta

  19. Late Neanderthals at Jarama VI (central Iberia)?

    Science.gov (United States)

    Kehl, Martin; Burow, Christoph; Hilgers, Alexandra; Navazo, Marta; Pastoors, Andreas; Weniger, Gerd-Christian; Wood, Rachel; Jordá Pardo, Jesús F.

    2013-09-01

    Previous geochronological and archaeological studies on the rock shelter Jarama VI suggested a late survival of Neanderthals in central Iberia and the presence of lithic assemblages of Early Upper Paleolithic affinity. New data on granulometry, mineralogical composition, geochemical fingerprints and micromorphology of the sequence corroborate the previous notion that the archaeological units JVI.2.1 to JVI.2.3 are slackwater deposits of superfloods, which did not experience significant post-depositional changes, whereas the artifact-rich units JVI.3 and JVI.1 mainly received sediment inputs by sheetwash and cave spall. New AMS radiocarbon measurements on three samples of cut-marked bone using the ultrafiltration technique yielded ages close to, or beyond, the limit of radiocarbon dating at ca. 50 14C ka BP, and hence suggest much higher antiquity than assumed previously. Furthermore, elevated temperature post-IR IRSL luminescence measurements on K feldspars yielded burial ages for subunits JVI.2.2 and JVI.2.3 between 50 and 60 ka. Finally, our reappraisal of the stone industry strongly suggests that the whole sequence is of Mousterian affinity. In conclusion, Jarama VI most probably does not document a late survival of Neanderthals nor an Early Upper Paleolithic occupation in central Iberia, but rather indicates an occupation breakdown after the Middle Paleolithic.

  20. Investigation of uranium (VI) adsorption by polypyrrole.

    Science.gov (United States)

    Abdi, S; Nasiri, M; Mesbahi, A; Khani, M H

    2017-06-15

    The purpose of this study was to investigate the adsorption of uranium (VI) ions on the polypyrrole adsorbent. Polypyrrole was synthesized by a chemical method using polyethylene glycol, sodium dodecylbenzenesulfonate, and cetyltrimethylammonium bromide as the surfactant and iron (III) chloride as an oxidant in the aqueous solution. The effect of various surfactants on the synthesized polymers and their performance as the uranium adsorbent were investigated. Adsorbent properties were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) techniques. The effect of different parameters such as pH, contact time, initial metal ion concentrations, adsorbent dose, and the temperature was investigated in the batch system for uranium adsorption process. It has been illustrated that the adsorption equilibrium time is 7min. The results showed that the Freundlich model had the best agreement and the maximum adsorption capacity of polypyrrole for uranium (VI) was determined 87.72mg/g from Langmuir isotherm. In addition, the mentioned adsorption process was fast and the kinetic data were fitted to the Pseudo first and second order models. The adsorption kinetic data followed the pseudo-second-order kinetic model. Moreover, the thermodynamic parameters ΔG(0), ΔH(0) and ΔS(0) showed that the uranium adsorption process by polypyrrole was endothermic and spontaneous. Copyright © 2017. Published by Elsevier B.V.

  1. -and -turns in proteins revisited: A new set of amino acid turn ...

    Indian Academy of Sciences (India)

    -turns (7153) and -turns (911) extracted from these proteins were used to derive a revised set of type-dependent amino acid positional preferences and potentials. Compared with previous results, the preference for proline, methionine and tryptophan has increased and the preference for glutamine, valine, glutamic acid ...

  2. Driving simulator study of J-Turn acceleration/deceleration lane and U-turn spacing.

    Science.gov (United States)

    2016-11-01

    Carlos Sun : http://orcid.org/0000-0002-8857-9648 : The J-turn, also known as RCUT (Restricted Crossing U-Turn) and Superstreet, is an innovative geometric design that can improve intersection safety. Even though this design has been in use in severa...

  3. Interaction of monosaccharides and related compounds with oxocations of Mo(VI), W(VI) and U(VI) studied by NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Geraldes, C.F.G.C.; Castro, M.M.C.A.; Saraiva, M.E.; Aureliano, M.; Dias, B.A.

    1988-05-01

    Proton, /sup 13/C and /sup 31/P nuclear magnetic resonance spectroscopy has been used to study the complexation of Mo(VI), W(VI) and U(VI) oxocations with various aldoses, cyclic polyols and ribose-5-phosphate in aqueous solution. The aldoses D-mannose, D-lyxose and D-ribose form tridentate complexes with Mo(VI) and W(VI) at pH similarly ordered 5, via the 1,2,3-hydroxyl groups, which are cis to each other in these sugars. Other aldoses, like D-arabinose, D-glucose, D-xylose and D-galactose form weaker bidentate complexes with those ions because they can only use the 1 and 3-cis hydroxyl groups in metal binding. These bidentate interactions also take place in the binding of U(VI) to D-mannose and D-ribose, at pH similarly ordered 10. However, sugars having 1,3,5-hydroxyl groups in the cis position do not form stable chelates with these oxocations, possibly due to steric crowding. In the case of ribose-5-phosphate, the phosphate group is the exclusive binding site for the three oxocations, except for U(VI) at very basic pH (pH > 10), where the hydroxyl groups also interact with UO/sub 2//sup 2 +/.

  4. Immediate Effects of Clock-Turn Strategy on the Pattern and Performance of Narrow Turning in Persons With Parkinson Disease.

    Science.gov (United States)

    Yang, Wen-Chieh; Hsu, Wei-Li; Wu, Ruey-Meei; Lin, Kwan-Hwa

    2016-10-01

    Turning difficulty is common in people with Parkinson disease (PD). The clock-turn strategy is a cognitive movement strategy to improve turning performance in people with PD despite its effects are unverified. Therefore, this study aimed to investigate the effects of the clock-turn strategy on the pattern of turning steps, turning performance, and freezing of gait during a narrow turning, and how these effects were influenced by concurrent performance of a cognitive task (dual task). Twenty-five people with PD were randomly assigned to the clock-turn or usual-turn group. Participants performed the Timed Up and Go test with and without concurrent cognitive task during the medication OFF period. The clock-turn group performed the Timed Up and Go test using the clock-turn strategy, whereas participants in the usual-turn group performed in their usual manner. Measurements were taken during the 180° turn of the Timed Up and Go test. The pattern of turning steps was evaluated by step time variability and step time asymmetry. Turning performance was evaluated by turning time and number of turning steps. The number and duration of freezing of gait were calculated by video review. The clock-turn group had lower step time variability and step time asymmetry than the usual-turn group. Furthermore, the clock-turn group turned faster with fewer freezing of gait episodes than the usual-turn group. Dual task increased the step time variability and step time asymmetry in both groups but did not affect turning performance and freezing severity. The clock-turn strategy reduces turning time and freezing of gait during turning, probably by lowering step time variability and asymmetry. Dual task compromises the effects of the clock-turn strategy, suggesting a competition for attentional resources.Video Abstract available for more insights from the authors (see Supplemental Digital Content 1, http://links.lww.com/JNPT/A141).

  5. Beta and Gamma Gradients

    DEFF Research Database (Denmark)

    Løvborg, Leif; Gaffney, C. F.; Clark, P. A.

    1985-01-01

    Experimental and/or theoretical estimates are presented concerning, (i) attenuation within the sample of beta and gamma radiation from the soil, (ii) the gamma dose within the sample due to its own radioactivity, and (iii) the soil gamma dose in the proximity of boundaries between regions...... of differing radioactivity. It is confirmed that removal of the outer 2 mm of sample is adequate to remove influence from soil beta dose and estimates are made of the error introduced by non-removal. Other evaluations include variation of the soil gamma dose near the ground surface and it appears...

  6. Melting of a beta-hairpin peptide using isotope-edited 2D IR spectroscopy and simulations.

    NARCIS (Netherlands)

    Smith, A.W.; Lessing, J.; Ganim, Z.; Peng, C.S.; Tokmakoff, A.; Roy, S.; Jansen, T.L.Th.A.; Knoester, J.

    2010-01-01

    Isotope-edited two-dimensional infrared spectroscopy has been used to characterize the conformational heterogeneity of the beta-hairpin peptide TrpZip2 (TZ2) across its thermal unfolding transition. Four isotopologues were synthesized to probe hydrogen bonding and solvent exposure of the beta-turn

  7. Melting of a beta-Hairpin Peptide Using Isotope-Edited 2D IR Spectroscopy and Simulations

    NARCIS (Netherlands)

    Smith, Adam W.; Lessing, Joshua; Ganim, Ziad; Peng, Chunte Sam; Tokmakoff, Andrei; Roy, Santanu; Jansen, Thomas L. C.; Knoester, Jasper

    2010-01-01

    Isotope-edited two-dimensional infrared spectroscopy has been used! to characterize the conformational heterogeneity of the beta-hairpin peptide TrpZip2 (17.2) across its thermal unfolding transition Four isotopologues were synthesized to probe hydrogen bonding and solvent exposure of the beta-turn

  8. Effect of turning angle on performance of 2-D turning diffuser via Asymptotic Computational Fluid Dynamics

    Science.gov (United States)

    Khong, Y. T.; Nordin, N.; Seri, S. M.; Mohammed, A. N.; Sapit, A.; Taib, I.; Abdullah, K.; Sadikin, A.; Razali, M. A.

    2017-09-01

    The present work aims to numerically investigate the effect of varying turning angle, ϕ = 30° - 90° on the performance of 2-D turning diffuser and to develop the performance correlations via integrating the turning angle using Asymptotic Computational Fluid Dynamics (ACFD) technique. Standard k-ε adopting enhanced wall treatment of y+ ≈ 1.1 appeared as the best validated model to represent the actual cases with deviation of ±4.7%. Results show that the pressure recovery, Cp and flow uniformity, σout are distorted of respectively 37% and 28% with the increment of turning angle from 30° to 90°. The flow separation starts to emerge within the inner wall, S=0.91Lin/W1 when 45° turning diffuser is applied and its scale is enlarged by further increasing the turning angle. The performance correlations of 2-D turning diffuser are successfully developed with deviation to the full CFD solution approximately of ±7.1%.

  9. Measurement of tool forces in diamond turning

    Energy Technology Data Exchange (ETDEWEB)

    Drescher, J.; Dow, T.A.

    1988-12-01

    A dynamometer has been designed and built to measure forces in diamond turning. The design includes a 3-component, piezoelectric transducer. Initial experiments with this dynamometer system included verification of its predicted dynamic characteristics as well as a detailed study of cutting parameters. Many cutting experiments have been conducted on OFHC Copper and 6061-T6 Aluminum. Tests have involved investigation of velocity effects, and the effects of depth and feedrate on tool forces. Velocity has been determined to have negligible effects between 4 and 21 m/s. Forces generally increase with increasing depth of cut. Increasing feedrate does not necessarily lead to higher forces. Results suggest that a simple model may not be sufficient to describe the forces produced in the diamond turning process.

  10. When attempts at robbing prey turn fatal

    Science.gov (United States)

    Dejean, Alain; Corbara, Bruno; Azémar, Frédéric; Carpenter, James M.

    2012-07-01

    Because group-hunting arboreal ants spread-eagle insect prey for a long time before retrieving them, these prey can be coveted by predatory flying insects. Yet, attempting to rob these prey is risky if the ant species is also an effective predator. Here, we show that trying to rob prey from Azteca andreae workers is a fatal error as 268 out of 276 potential cleptobionts (97.1 %) were captured in turn. The ant workers hunt in a group and use the "Velcro®" principle to cling firmly to the leaves of their host tree, permitting them to capture very large prey. Exceptions were one social wasp, plus some Trigona spp. workers and flies that landed directly on the prey and were able to take off immediately when attacked. We conclude that in this situation, previously captured prey attract potential cleptobionts that are captured in turn in most of the cases.

  11. Turning Mechanics During Swimming by Oblate Hydromedusae

    Science.gov (United States)

    Costello, J.; Colin, S.; Sutherland, K.; Gemmell, B. J.

    2016-02-01

    Maneuverability is critical to the success of many species. Selective forces acting over millions of years have resulted in a range of capabilities currently unmatched by machines. Thus, understanding animal control of fluids for maneuvering has both biological and engineering applications. Medusae are radially symmetrical swimmers that must use asymmetric body motions to change direction during turning maneuvers. But what types of asymmetric motions are useful and how do they interact with surrounding fluids to generate rotational forces? We used high speed digital particle image velocimetry (DPIV) to investigate comparative swimming patterns of three hydromedusan species (Aequorea victoria, Clytia gregaria and Mitrocoma cellularia). We provide evidence for consistent animal-fluid interactions that underlie turning mechanics of oblate hydromedusae and provide new insights into the modulation and control of vorticity for low-speed animal maneuvering.

  12. Hvad skal vi med skønlitteraturen?

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe; Oksbjerg, Marianne

    2012-01-01

    didaktiske læremidler, der produceres i disse år, lægges der ikke op til en udnyttelse af skønlitteraturens potentiale for at danne eleverne til demokratiske borgere. I denne artikel beskriver vi, hvad der er galt med læremidlerne. Desuden skitserer vi kriterier for formulering af elevopgaver, der lægger op...

  13. Detoxification of chromium (VI) in coastal water using lignocellulosic ...

    African Journals Online (AJOL)

    In the present study, attempts have been made to harness lignocellulosic agricultural waste material (bagasse) for the removal of chromium (VI) from highly saline coastal water used for aquacultural practices using brackish water. Five different products prepared from bagasse were evaluated for the detoxification of Cr(VI) ...

  14. Biosorption of chromium(VI) using immobilized Bacillius subtilis and ...

    African Journals Online (AJOL)

    Therefore, the batch removal of Cr (VI) from environment water bodies becomes necessary. Its removal from aqueous solution using immobilized Bacillus subtilis (IBBS), Pseudomonas aeruginosa (IPBS), mixed biomass (IMBS) and Alginate alone (IABS) was carried out. The conditions of influence of initial Cr (VI) ...

  15. Predicting chromium (VI) adsorption rate in the treatment of liquid ...

    African Journals Online (AJOL)

    The adsorption rate of chromium (VI) on commercial activated carbon during the treatment of the flocculation effluent of liquid-phase oil-based drill-cuttings has been investigated in terms of contact time and initial chromium (VI) ion concentration. Homogenizing 1 g of the activated carbon with 100 ml of the flocculation ...

  16. Moderate selenium dosing inhibited chromium (VI) toxicity in chicken liver.

    Science.gov (United States)

    Wang, Yang; Liu, Yongxia; Wan, Huiyu; Zhu, Yiran; Chen, Peng; Hao, Pan; Cheng, Ziqiang; Liu, Jianzhu

    2017-08-01

    This study aimed to clarify the effect of selenium (Se) on chromium (VI) [Cr(VI)]-induced damage in chicken liver. A total of 105 chickens were randomly divided into seven groups of 15. Group I received deionized water; group II received Cr(VI) (7.83 mg/kg/d) alone; and other groups orally received both Cr(VI) (7.83 mg/kg/d) and Se of different doses (0.14, 0.29, 0.57, 1.14, and 2.28 mg/kg/d). The levels of superoxide dismutase (SOD), glutathione (GSH), malondialdehyde (MDA), Ca2+ -ATPase, and mitochondrial membrane potential (MMP) were measured. Results showed that Cr(VI) increased MDA content and decreased GSH content, T-SOD activity, Ca2+ -ATPase activity, and MMP level. Meanwhile, Se co-treatment (0.14, 0.29, and 0.57 mg/kg/d) increased the viability of the above indicators compared with Cr(VI)-treatment alone. In addition, histopathologic examination revealed that Cr(VI) can cause liver damage, whereas Se supplementation of moderate dose inhibited this damage. This study confirmed that Se exerted protective effect against Cr(VI)-induced liver damage. © 2017 Wiley Periodicals, Inc.

  17. Dynamics of a steel turning process

    Science.gov (United States)

    Litak, Grzegorz; Rusinek, Rafał

    This paper explores the cutting force oscillations. Forces have been measured during the stainless steel turning. We provide the results of standard statistical analysis of the corresponding time series together with their recurrence properties. We claim that the system, which is initially in a regular vibration region for some fairly larger cutting depth, is unstable to chaotic oscillation appearance. This could have the important implication to the process control procedure.

  18. Turning neurons into a nervous system.

    Science.gov (United States)

    Grove, Elizabeth A

    2008-07-01

    The RIKEN Center for Developmental Biology recently held its 2008 Symposium ;Turning Neurons into a Nervous System' in Kobe, Japan. The program, organized by Masatoshi Takeichi, Joshua Sanes, Hideki Enomoto and Raj Ladher, provided a rich sampling from current work in developmental neurobiology. Researchers from Japan, Europe and the USA gathered at this meeting to share insights into neural development and to admire the opening of the cherry blossom season.

  19. Rekayasa Cnc Turning Sebagai Media Pembelajaran Cnc

    OpenAIRE

    Purwoko, Bambang Setiyo Hari

    2016-01-01

    Engineering CNC Turning aims; (1) produce a prototype, which is capable of a teaching aids, and resources of CNC programming. Engineering conducted following the procedures Research and Development (R & D) expressed Borg and Gall. Starting with a needs study of teaching aids/media of CNC programming; defining products (define); designing a system and form (design); develop products and test its performance (develop); and the revision/ improvement of product performance (revise). Results of th...

  20. Turning points in climate change adaptation

    Directory of Open Access Journals (Sweden)

    Saskia Elisabeth. Werners

    2015-12-01

    Full Text Available Concerned decision makers increasingly pose questions as to whether current management practices are able to cope with climate change and increased climate variability. This signifies a shift in the framing of climate change from asking what its potential impacts are to asking whether it induces policy failure and unacceptable change. In this paper, we explore the background, feasibility, and consequences of this new framing. We focus on the specific situation in which a social-political threshold of concern is likely to be exceeded as a result of climate change, requiring consideration of alternative strategies. Action is imperative when such a situation is conceivable, and at this point climate change becomes particularly relevant to decision makers. We call this situation an "adaptation turning point." The assessment of adaptation turning points converts uncertainty surrounding the extent of a climate impact into a time range over which it is likely that specific thresholds will be exceeded. This can then be used to take adaptive action. Despite the difficulty in identifying adaptation turning points and the relative newness of the approach, experience so far suggests that the assessment generates a meaningful dialogue between stakeholders and scientists. Discussion revolves around the amount of change that is acceptable; how likely it is that unacceptable, or more favorable, conditions will be reached; and the adaptation pathways that need to be considered under these circumstances. Defining and renegotiating policy objectives under climate change are important topics in the governance of adaptation.

  1. FCC-hh turn-around cycle

    CERN Document Server

    Alemany Fernandez, Reyes; Bartmann, Wolfgang; Buffat, Xavier; Niemi, Arto; Schulte, Daniel; Solfaroli Camillocci, Matteo; Stoel, Linda

    2016-01-01

    The turn-around cycle time of a collider is defined as the time spent between the end of stable beams and the start of the next stable beams period, and its calculation is of fundamental importance. On one side it is a crucial ingredient for the computation of the optimal time spent in luminosity production, which defines the integrated luminosity per fill or store. On the other side, combined with the availability and reliability of the machine, it allows to perform a detailed breakdown of the operational performance of the collider over an operational season, i.e. percentage of time in stable beams and beam in the machine with respect to down time. This paper presents a preliminary operational cycle definition for the hadron-hadron Future Circular Collider, as a base line for estimating the corresponding turn-around time. The cycle definition is based on the Large Hadron Collider (LHC) operational cycle. Two turn-around times are presented, the theoretical one and a more realistic one based on the LHC exper...

  2. Trichoderma .beta.-glucosidase

    Science.gov (United States)

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2006-01-03

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  3. Beta thalassemia - a review

    Directory of Open Access Journals (Sweden)

    R Jha

    2014-09-01

    Full Text Available Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or more of the globin chains. About 1.5% of the global population (80 to 90 million people are carriers of beta Thalassemia. More than 200 mutations are described in beta thalassemia. However not all mutations are common in different ethnic groups. The only effective way to reduce burden of thalassemia is to prevent birth of homozygotes. Diagnosis of beta thalassemia can be done by fetal DNA analysis for molecular defects of beta thalassemia or by fetal blood analysis. Hematopoietic stem cell transplantation is the only available curative approach for Thalassemia. Many patients with thalassemia in underdeveloped nations die in childhood or adolescence. Programs that provide acceptable care, including transfusion of safe blood and supportive therapy including chelation must be established.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11609 Journal of Pathology of Nepal; Vol.4,No. 8 (2014 663-671

  4. beta nur pratiwi

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. BETA NUR PRATIWI. Articles written in Pramana – Journal of Physics. Volume 88 Issue 2 February 2017 pp 25 Regular. Asymptotic iteration method for the modified Pöschl–Teller potential and trigonometric Scarf II non-central potential in the Dirac equation spin symmetry.

  5. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    2015-11-27

    Nov 27, 2015 ... Abstract. The physics potential of neutrinoless double beta decay is discussed. Furthermore, experimental considerations as well as the current status of experiments are presented. Finally, an outlook towards the future, work on nuclear matrix elements and alternative processes is given.

  6. Double beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Bryman, D.; Picciotto, C.

    1978-01-01

    The problem of double beta decay is reviewed with emphasis on its relevance to lepton number conservation. Recently, the ratio of the double beta-decay half-lives of /sup 128/Te and /sup 130/Te has been measured in a geological experiment and a limit for the ratio of the neutrinoless rate to the total rate for /sup 82/Se decay has been obtained from a direct-detection experiment. For the first time, these results show conclusively that double beta decay is not primarily a lepton-number-violating neutrinoless process. However, they also do not agree with calculations which assume that only lepton-number-conserving two-neutrino double beta decay occurs. The conclusion that lepton number conservation is violated is suggested by limited experimental information. By considering contributions to the total rate from both the two-neutrino and the neutrinoless channels, we obtain data which are consistent with a lepton nonconservation parameter of order eta=3.5 x 10/sup -5/. Roughly the same value of eta is obtained by assuming that the decay occurs either via lepton emission from two nucleons or via emission from a resonance in the nucleus.

  7. Beta Cell Breakthroughs

    Science.gov (United States)

    ... raise the hopes of people with type 1 diabetes that a cure is right around the corner. First the beta ... element: Two of his children have type 1 diabetes. After his son was diagnosed with the disease as an infant, Melton devoted his career to searching for a cure. More than 20 years have gone by, but ...

  8. Museo del oro: viñetas

    Directory of Open Access Journals (Sweden)

    Les Field

    2013-01-01

    Full Text Available En enero de 2011 convocamos a un grupo internacional de académicos/activistas para discutir en Colombia las complejidades de la relación entre arqueología, excavaciones “ilícitas”, museos y comunidades indígenas desde una mirada comparativa. El taller de tres días tuvo lugar en Bogotá y Villa de Leyva. Uno de los eventos programados durante los dos días de la parte bogotana del taller fue una visita al Museo del Oro. En el restaurante del museo conversamos sobre lo que acabábamos de ver, sentir y pensar, y surgieron estas impresiones en las que el estupor convive con un fuerte deseo por decir algo. En Villa de Leyva nació la idea de que cada uno de nosotros transcribiera sus emociones en formato de viñeta.

  9. A Video Tour through ViSta 6.4

    Directory of Open Access Journals (Sweden)

    J. Gabriel Molina

    2004-12-01

    Full Text Available This paper offers a visual tour throughout ViSta 6.4, a freeware statistical program based on Lisp-Stat and focused on techniques for statistical visualization (Young 2004. This travel around ViSta is based on screen recordings that illustrate the main features of the program in action. The following aspects of ViSta 6.4 are displayed: the program's interface (ViSta's desktop, menubar and pop-up menus, help system; its data management capabilities (data input and editing, data transformations; features associated to data analysis (data description, statistical modeling; and the options for Lisp-Stat development in ViSta. The video recordings associated to this tour (.wmv files can be visualized at http://www.jstatsoft.org/v13/i08/ using the Internet Explorer navigator, or by clicking on the figures in the paper.

  10. Biosorption of uranium (VI) by immobilized Aspergillus fumigatus beads

    Energy Technology Data Exchange (ETDEWEB)

    Wang Jingsong, E-mail: xhwjs@163.co [School of Urban Construction, University of South China, 28 West Changsheng Road, Hengyang, Hunan 421001 (China) and Hunan Key Laboratory of Pollution Control and Resource Reuse, University of South China, Henyang, Hunan 421001 (China); Hu Xinjiang [School of Urban Construction, University of South China, 28 West Changsheng Road, Hengyang, Hunan 421001 (China); College of Environmental Science and Engineering, Hunan University, Changsha 410082 (China); Liu Yunguo [College of Environmental Science and Engineering, Hunan University, Changsha 410082 (China); Xie Shuibo [School of Urban Construction, University of South China, 28 West Changsheng Road, Hengyang, Hunan 421001 (China); Hunan Key Laboratory of Pollution Control and Resource Reuse, University of South China, Henyang, Hunan 421001 (China); Bao Zhenglei [School of Urban Construction, University of South China, 28 West Changsheng Road, Hengyang, Hunan 421001 (China)

    2010-06-15

    Biosorption of uranium (VI) ions by immobilized Aspergillus fumigatus beads was investigated in a batch system. The influences of solution pH, biosorbent dose, U (VI) concentration, and contact time on U (VI) biosorption were studied. The results indicated that the adsorption capacity was strongly affected by the solution pH, the biosorbent dose and initial U (VI) concentration. Optimum biosorption was observed at pH 5.0, biosrobent dose (w/v) 2.5%, initial U (VI) concentration 60 mg L{sup -1}. Biosorption equilibrium was established in 120 min. The adsorption process conformed to the Freunlich and Temkin isothermal adsorption models. The dynamic adsorption model conformed to pseudo-second order model.

  11. Beta cell adaptation in pregnancy

    DEFF Research Database (Denmark)

    Nielsen, Jens Høiriis

    2016-01-01

    Pregnancy is associated with a compensatory increase in beta cell mass. It is well established that somatolactogenic hormones contribute to the expansion both indirectly by their insulin antagonistic effects and directly by their mitogenic effects on the beta cells via receptors for prolactin...... and growth hormone expressed in rodent beta cells. However, the beta cell expansion in human pregnancy seems to occur by neogenesis of beta cells from putative progenitor cells rather than by proliferation of existing beta cells. Claes Hellerström has pioneered the research on beta cell growth for decades...... in the expansion of the beta cell mass in human pregnancy, and the relative roles of endocrine factors and nutrients....

  12. Investigation of uranium (VI) adsorption by polypyrrole

    Energy Technology Data Exchange (ETDEWEB)

    Abdi, S. [Faculty of Chemical, Petroleum and Gas Engineering, Semnan University, Semnan 35195-363 (Iran, Islamic Republic of); Nasiri, M., E-mail: mnasiri@semnan.ac.ir [Faculty of Chemical, Petroleum and Gas Engineering, Semnan University, Semnan 35195-363 (Iran, Islamic Republic of); Mesbahi, A. [Faculty of Chemical, Petroleum and Gas Engineering, Semnan University, Semnan 35195-363 (Iran, Islamic Republic of); Khani, M.H. [Nuclear Fuel Cycle Research School, Nuclear Science and Technology Research Institute, Tehran, 14395-836 (Iran, Islamic Republic of)

    2017-06-15

    Highlights: • The adsorbent (polypyrrole) was synthesized by a chemical method using PEG, DBSNa and CTAB as the surfactant. • The solution pH was one of the most important parameters affecting the adsorption of uranium. • The CTAB provided higher removal percentage compared with the other surfactants. • The maximum adsorption capacity obtained from Langmuir isotherm was 87.72 mg/g. • The pseudo second-order model fitted well with the adsorption kinetic of polypyrrole to uranium. - Abstract: The purpose of this study was to investigate the adsorption of uranium (VI) ions on the polypyrrole adsorbent. Polypyrrole was synthesized by a chemical method using polyethylene glycol, sodium dodecylbenzenesulfonate, and cetyltrimethylammonium bromide as the surfactant and iron (III) chloride as an oxidant in the aqueous solution. The effect of various surfactants on the synthesized polymers and their performance as the uranium adsorbent were investigated. Adsorbent properties were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) techniques. The effect of different parameters such as pH, contact time, initial metal ion concentrations, adsorbent dose, and the temperature was investigated in the batch system for uranium adsorption process. It has been illustrated that the adsorption equilibrium time is 7 min. The results showed that the Freundlich model had the best agreement and the maximum adsorption capacity of polypyrrole for uranium (VI) was determined 87.72 mg/g from Langmuir isotherm. In addition, the mentioned adsorption process was fast and the kinetic data were fitted to the Pseudo first and second order models. The adsorption kinetic data followed the pseudo-second-order kinetic model. Moreover, the thermodynamic parameters ΔG{sup 0}, ΔH{sup 0} and ΔS{sup 0} showed that the uranium adsorption process by polypyrrole was endothermic and spontaneous.

  13. Six-fold Coordinated Carbon Dioxide VI

    Energy Technology Data Exchange (ETDEWEB)

    Iota, V; Yoo, C; Klepeis, J; Jenei, Z

    2006-03-01

    Under standard conditions, carbon dioxide (CO{sub 2}) is a simple molecular gas and an important atmospheric constituent while silicon dioxide (SiO{sub 2}) is a covalent solid, and represents one of the fundamental minerals of the planet. The remarkable dissimilarity between these two group IV oxides is diminished at higher pressures and temperatures as CO{sub 2} transforms to a series of solid phases, from simple molecular to a fully covalent extended-solid V, structurally analogous to SiO{sub 2} tridymite. Here, we present the discovery of a new extended-solid phase of carbon dioxide (CO{sub 2}): a six-fold coordinated stishovite-like phase VI, obtained by isothermal compression of associated CO{sub 2}-II above 50GPa at 530-650K. Together with the previously reported CO{sub 2}-V and a-carbonia, this new extended phase indicates a fundamental similarity between CO{sub 2}--a prototypical molecular solid, and SiO{sub 2}--one of Earth's fundamental building blocks. The phase diagram suggests a limited stability domain for molecular CO{sub 2}-I, and proposes that the conversion to extended-network solids above 40-50 GPa occurs via intermediate phases II, III, and IV. The crystal structure of phase VI suggests strong disorder along the caxis in stishovite-like P4{sub 2}/mnm, with carbon atoms manifesting an average six-fold coordination within the framework of sp{sup 3} hybridization.

  14. ADSORPTION OF Cr(VI ON BLACK WATER

    Directory of Open Access Journals (Sweden)

    Rasti Januarita

    2010-06-01

    Full Text Available The effect of initial concentration of Cr(VI on adsorption to black water of Gambut, District of Banjar, South Borneo has been investigated, as well as interaction between Cr(VI species and functional black water organic fraction. The initial work was optimization of Cr(VI determination using UV-Visible Spectrophotometry with diphenylcarbacide as complexing agent and preparation of black water using mixture of 2% HCl and 5% HF with HCl-HF ratio of 1 : 1 (v/v. The quantity of Cr(VI species adsorbed on black water was calculated by determining the amount of Cr(VI species in solution before and after interaction. The functional groups in interaction between Cr(VI species and black water organic fraction was studied qualitatively using infrared spectroscopy. The results showed that optimum condition for Cr(VI species analysis using UV-Visible spectrophotometry with diphenylcarbacide as complexing agent was at wave length of 540 nm, pH 1,5, 15 - 60 minutes at which complex remain stable, and minimum mol ratio of diphenylcarbacide : Cr(VI 45 : 1, and has a sensitivity of 1.134 mg/L and detection limit of 0.00495 mg/L. The analysis was not affected by the presence of Cr(III in concentration less than 40 times of Cr(VI concentration. After treatment with HCl-HF the quantity of black water organic fraction showing humic acid properties decreased 0,1998 percent. Organic fraction of black water used adsorpted Cr(VIwith capacity of 4,050 mg/g.   Keywords: Adsorption, Cr(VI, Black Water

  15. Beta emitters and radiation protection

    DEFF Research Database (Denmark)

    Jødal, Lars

    2009-01-01

    BACKGROUND. Beta emitters, such as 90Y, are increasingly being used for cancer treatment. However, beta emitters demand other precautions than gamma emitters during preparation and administration, especially concerning shielding. AIM. To discuss practical precautions for handling beta emitters...... on the outside of the primary shielding material. If suitable shielding is used and larger numbers of handlings are divided among several persons, then handling of beta emitters can be a safe procedure....

  16. Lattice modeling and calibration with turn-by-turn orbit data

    Directory of Open Access Journals (Sweden)

    Xiaobiao Huang

    2010-11-01

    Full Text Available A new method that explores turn-by-turn beam position monitor (BPM data to calibrate lattice models of accelerators is proposed. The turn-by-turn phase space coordinates at one location of the ring are first established using data from two BPMs separated by a simple section with a known transfer matrix, such as a drift space. The phase space coordinates are then tracked with the model to predict positions at other BPMs, which can be compared to measurements. The model is adjusted to minimize the difference between the measured and predicted orbit data. BPM gains and rolls are included as fitting variables. This technique can be applied to either the entire or a section of the ring. We have tested the method experimentally on a part of the SPEAR3 ring.

  17. Technology-derived storage solutions for stabilizing insulin in extreme weather conditions I: the ViViCap-1 device.

    Science.gov (United States)

    Pfützner, Andreas; Pesach, Gidi; Nagar, Ron

    2017-06-01

    Injectable life-saving drugs should not be exposed to temperatures 30°C/86°F. Frequently, weather conditions exceed these temperature thresholds in many countries. Insulin is to be kept at 4-8°C/~ 39-47°F until use and once opened, is supposed to be stable for up to 31 days at room temperature (exception: 42 days for insulin levemir). Extremely hot or cold external temperature can lead to insulin degradation in a very short time with loss of its glucose-lowering efficacy. Combined chemical and engineering solutions for heat protection are employed in ViViCap-1 for disposable insulin pens. The device works based on vacuum insulation and heat consumption by phase-change material. Laboratory studies with exposure of ViViCap-1 to hot outside conditions were performed to evaluate the device performance. ViViCap-1 keeps insulin at an internal temperature change process and 'recharges' the device for further use. ViViCap-1 performed within its specifications. The small and convenient device maintains the efficacy and safety of using insulin even when carried under hot weather conditions.

  18. A novel fluorescent "Turn-Off/Turn-On" system for the detection of acid phosphatase activity.

    Science.gov (United States)

    Guo, Pu; Yan, Shengyong; Zhou, Yimin; Wang, Changcheng; Xu, Xiaowei; Weng, Xiaocheng; Zhou, Xiang

    2013-06-21

    Acid phosphatase (ACP) can be sensitively, conveniently and efficiently detected via a new fluorescent "Turn-Off/Turn-On" system. Inexpensive (NaPO(3))(6) is carefully introduced into this system as a quencher of the aggregation-caused quenching (ACQ) probe. In our method, the limit of detection (LOD) is quite low for detecting ACP, which is an important biomarker and indication of several diseases.

  19. The FUSE Survey of 0 VI in the Galactic Halo

    Science.gov (United States)

    Sonneborn, George; Savage, B. D.; Wakker, B. P.; Sembach, K. R.; Jenkins, E. B.; Moos, H. W.; Shull, J. M.

    2003-01-01

    This paper summarizes the results of the Far-Ultraviolet Spectroscopic Explorer (FUSE) program to study 0 VI in the Milky Way halo. Spectra of 100 extragalactic objects and two distant halo stars are analyzed to obtain measures of O VI absorption along paths through the Milky Way thick disk/halo. Strong O VI absorption over the velocity range from -100 to 100 km/s reveals a widespread but highly irregular distribution of O VI, implying the existence of substantial amounts of hot gas with T approx. 3 x 10(exp 5) K in the Milky Way thick disk/halo. The overall distribution of O VI is not well described by a symmetrical plane-parallel layer of patchy O VI absorption. The simplest departure from such a model that provides a reasonable fit to the observations is a plane-parallel patchy absorbing layer with an average O VI mid-plane density of n(sub 0)(O VI) = 1.7 x 10(exp -2)/cu cm, a scale height of approx. 2.3 kpc, and a approx. 0.25 dex excess of O VI in the northern Galactic polar region. The distribution of O VI over the sky is poorly correlated with other tracers of gas in the halo, including low and intermediate velocity H I, Ha emission from the warm ionized gas at approx. l0(exp 4) K, and hot X-ray emitting gas at approx. l0(exp 6) K . The O VI has an average velocity dispersion, b approx. 60 km/s and standard deviation of 15 km/s. Thermal broadening alone cannot explain the large observed profile widths. A combination of models involving the radiative cooling of hot fountain gas, the cooling of supernova bubbles in the halo, and the turbulent mixing of warm and hot halo gases is required to explain the presence of O VI and other highly ionized atoms found in the halo. The preferential venting of hot gas from local bubbles and superbubbles into the northern Galactic polar region may explain the enhancement of O VI in the North.

  20. Conserved Water-mediated Hydrogen Bond Network between TM-I, -II, -VI, and -VII in 7TM Receptor Activation*

    Science.gov (United States)

    Nygaard, Rie; Valentin-Hansen, Louise; Mokrosinski, Jacek; Frimurer, Thomas M.; Schwartz, Thue W.

    2010-01-01

    Five highly conserved polar residues connected by a number of structural water molecules together with two rotamer micro-switches, TrpVI:13 and TyrVII:20, constitute an extended hydrogen bond network between the intracellular segments of TM-I, -II, -VI, and -VII of 7TM receptors. Molecular dynamics simulations showed that, although the fewer water molecules in rhodopsin were relatively movable, the hydrogen bond network of the β2-adrenergic receptor was fully loaded with water molecules that were surprisingly immobilized between the two rotamer switches, both apparently being in their closed conformation. Manipulations of the rotamer state of TyrVII:20 and TrpVI:13 demonstrated that these residues served as gates for the water molecules at the intracellular and extracellular ends of the hydrogen bond network, respectively. TrpVI:13 at the bottom of the main ligand-binding pocket was shown to apparently function as a catching trap for water molecules. Mutational analysis of the β2-adrenergic receptor demonstrated that the highly conserved polar residues of the hydrogen bond network were all important for receptor signaling but served different functions, some dampening constitutive activity (AsnI:18, AspII:10, and AsnVII:13), whereas others (AsnVII:12 and AsnVII:16) located one helical turn apart and sharing a water molecule were shown to be essential for agonist-induced signaling. It is concluded that the conserved water hydrogen bond network of 7TM receptors constitutes an extended allosteric interface between the transmembrane segments being of crucial importance for receptor signaling and that part of the function of the rotamer micro-switches, TyrVII:20 and TrpVI:13, is to gate or trap the water molecules. PMID:20395291

  1. Turning the Appliance Market Around towards A++

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen; Brange, Birgitte; Guldbrandsen, Tom

    2007-01-01

    energy efficient model within their specification, and 4) in the website are also listed the shops, where consumers can get the appliances at lowest prices. The latter was the most innovative and maybe also the most effective measure in the package. Results showed up as a permanent U-turn of the market...... in the course of a few years. Where models C, D, E earlier dominated the market, the A, A+ and A++, came to dominate as the standard models in stock. Consequently, their prices dropped significantly. The theory of a rational market behavior is based on some assumptions, one being that full information...

  2. The turn-around of Uninor

    OpenAIRE

    Gooderham, Paul N.; Ulset, Svein

    2013-01-01

    On October 29, 2008, Telenor of Norway announced its plans to enter the Indian mobile telecom market. Despite a strong start, revenue did not grow in line with business projections. In a highly congested market, price war caused rapidly shrinking margins. Something radical had to be done and quickly. A new cost-focused management team, headed by Telenor’s Asia chief Sigve Brekke, was appointed. In record time, they managed to turn Uninor into a dedicated ultra-low-cost basic services provide...

  3. Hatchability of chicken eggs as influenced by turning frequency in ...

    African Journals Online (AJOL)

    An experiment was conducted to determine the influence of turning frequency of chicken eggs on hatchability in hurricane lantern incubator. There were four treatments in which eggs were not turned in treatment one (control), those in treatment two were turned once daily (morning), treatment three turned twice daily ...

  4. The architecture of parallel beta-helices and related folds.

    Science.gov (United States)

    Jenkins, J; Pickersgill, R

    2001-10-01

    Three-dimensional structures have been determined of a large number of proteins characterized by a repetitive fold where each of the repeats (coils) supplies a strand to one or more parallel beta-sheets. Some of these proteins form superfamilies of proteins, which have probably arisen by divergent evolution from a common ancestor. The classical example is the family including four families of pectinases without obviously related primary sequences, the phage P22 tailspike endorhamnosidase, chrondroitinase B and possibly pertactin from Bordetella pertusis. These show extensive stacking of similar residues to give aliphatic, aromatic and polar stacks such as the asparagine ladder. This suggests that coils can be added or removed by duplication or deletion of the DNA corresponding to one or more coils and explains how homologous proteins can have different numbers of coils. This process can also account for the evolution of other families of proteins such as the beta-rolls, the leucine-rich repeat proteins, the hexapeptide repeat family, two separate families of beta-helical antifreeze proteins and the spiral folds. These families need not be related to each other but will share features such as relative untwisted beta-sheets, stacking of similar residues and turns between beta-strands of approximately 90 degrees often stabilized by hydrogen bonding along the direction of the parallel beta-helix.Repetitive folds present special problems in the comparison of structures but offer attractive targets for structure prediction. The stacking of similar residues on a flat parallel beta-sheet may account for the formation of amyloid with beta-strands at right-angles to the fibril axis from many unrelated peptides.

  5. Beta-thalassemia

    Directory of Open Access Journals (Sweden)

    Origa Raffaella

    2010-05-01

    Full Text Available Abstract Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main forms have been described: thalassemia major, thalassemia intermedia and thalassemia minor. Individuals with thalassemia major usually present within the first two years of life with severe anemia, requiring regular red blood cell (RBC transfusions. Findings in untreated or poorly transfused individuals with thalassemia major, as seen in some developing countries, are growth retardation, pallor, jaundice, poor musculature, hepatosplenomegaly, leg ulcers, development of masses from extramedullary hematopoiesis, and skeletal changes that result from expansion of the bone marrow. Regular transfusion therapy leads to iron overload-related complications including endocrine complication (growth retardation, failure of sexual maturation, diabetes mellitus, and insufficiency of the parathyroid, thyroid, pituitary, and less commonly, adrenal glands, dilated myocardiopathy, liver fibrosis and cirrhosis. Patients with thalassemia intermedia present later in life with moderate anemia and do not require regular transfusions. Main clinical features in these patients are hypertrophy of erythroid marrow with medullary and extramedullary hematopoiesis and its complications (osteoporosis, masses of erythropoietic tissue that primarily affect the spleen, liver, lymph nodes, chest and spine, and bone deformities and typical facial changes, gallstones, painful leg ulcers and increased predisposition to thrombosis. Thalassemia minor is clinically asymptomatic but some subjects may have moderate anemia. Beta-thalassemias are caused by point mutations or, more rarely

  6. The beta Gumbel distribution

    Directory of Open Access Journals (Sweden)

    Saralees Nadarajah

    2004-01-01

    Full Text Available The Gumbel distribution is perhaps the most widely applied statistical distribution for problems in engineering. In this paper, we introduce a generalization—referred to as the beta Gumbel distribution—generated from the logit of a beta random variable. We provide a comprehensive treatment of the mathematical properties of this new distribution. We derive the analytical shapes of the corresponding probability density function and the hazard rate function and provide graphical illustrations. We calculate expressions for the nth moment and the asymptotic distribution of the extreme order statistics. We investigate the variation of the skewness and kurtosis measures. We also discuss estimation by the method of maximum likelihood. We hope that this generalization will attract wider applicability in engineering.

  7. Beta-thalassemia.

    Science.gov (United States)

    Galanello, Renzo; Origa, Raffaella

    2010-05-21

    Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main forms have been described: thalassemia major, thalassemia intermedia and thalassemia minor. Individuals with thalassemia major usually present within the first two years of life with severe anemia, requiring regular red blood cell (RBC) transfusions. Findings in untreated or poorly transfused individuals with thalassemia major, as seen in some developing countries, are growth retardation, pallor, jaundice, poor musculature, hepatosplenomegaly, leg ulcers, development of masses from extramedullary hematopoiesis, and skeletal changes that result from expansion of the bone marrow. Regular transfusion therapy leads to iron overload-related complications including endocrine complication (growth retardation, failure of sexual maturation, diabetes mellitus, and insufficiency of the parathyroid, thyroid, pituitary, and less commonly, adrenal glands), dilated myocardiopathy, liver fibrosis and cirrhosis). Patients with thalassemia intermedia present later in life with moderate anemia and do not require regular transfusions. Main clinical features in these patients are hypertrophy of erythroid marrow with medullary and extramedullary hematopoiesis and its complications (osteoporosis, masses of erythropoietic tissue that primarily affect the spleen, liver, lymph nodes, chest and spine, and bone deformities and typical facial changes), gallstones, painful leg ulcers and increased predisposition to thrombosis. Thalassemia minor is clinically asymptomatic but some subjects may have moderate anemia. Beta-thalassemias are caused by point mutations or, more rarely, deletions in the beta

  8. Beta and muon decays

    Energy Technology Data Exchange (ETDEWEB)

    Galindo, A.; Pascual, P.

    1967-07-01

    These notes represent a series of lectures delivered by the authors in the Junta de Energia Nuclear, during the Spring term of 1965. They were devoted to graduate students interested in the Theory of Elementary Particles. Special emphasis was focussed into the computational problems. Chapter I is a review of basic principles (Dirac equation, transition probabilities, final state interactions.) which will be needed later. In Chapter II the four-fermion punctual Interaction is discussed, Chapter III is devoted to the study of beta-decay; the main emphasis is given to the deduction of the formulae corresponding to electron-antineutrino correlation, electron energy spectrum, lifetimes, asymmetry of electrons emitted from polarized nuclei, electron and neutrino polarization and time reversal invariance in beta decay. In Chapter IV we deal with the decay of polarized muons with radiative corrections. Chapter V is devoted to an introduction to C.V.C. theory. (Author)

  9. COM Support in BETA

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Component technologies based on binary units of independent production are some of the most important contributions to software architecture and reuse during recent years. Especially the COM technologies and the CORBA standard from the Object Management Group have contributed new and interesting ...... principles for software architecture, and proven to be useful in parctice. In this paper ongoing work with component support in the BETA language is described....

  10. Coroutine Sequencing in BETA

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun; Madsen, Ole Lehrmann; Møller-Pedersen, Birger

    In object-oriented programming, a program execution is viewed as a physical model of some real or imaginary part of the world. A language supporting object-oriented programming must therefore contain comprehensive facilities for modeling phenomena and concepts form the application domain. Many ap...... applications in the real world consist of objects carrying out sequential processes. Coroutines may be used for modeling objects that alternate between a number of sequential processes. The authors describe coroutines in BETA...

  11. Integration of BETA with Eclipse

    DEFF Research Database (Denmark)

    Andersen, Peter; Madsen, Ole Lehrmann; Enevoldsen, Mads Brøgger

    2004-01-01

    of language interoperability between Java and BETA is required. The first approach is to use the Java Native Interface and use C to bridge between Java and BETA. This results in a workable, but complicated solution. The second approach is to let the BETA compiler generate Java class files. With this approach......This paper presents language interoperability issues appearing in order to implement support for the BETA language in the Java-based Eclipse integrated development environment. One of the challenges is to implement plug-ins in BETA and be able to load them in Eclipse. In order to do this, some form...... it is possible to implement plug-ins in BETA and even inherit from Java classes. In the paper the two approaches are described together with part of the mapping from BETA to Java class files. http://www.sciencedirect.com/science/journal/15710661...

  12. Regulation of beta cell replication

    DEFF Research Database (Denmark)

    Lee, Ying C; Nielsen, Jens Høiriis

    2008-01-01

    Beta cell mass, at any given time, is governed by cell differentiation, neogenesis, increased or decreased cell size (cell hypertrophy or atrophy), cell death (apoptosis), and beta cell proliferation. Nutrients, hormones and growth factors coupled with their signalling intermediates have been...... suggested to play a role in beta cell mass regulation. In addition, genetic mouse model studies have indicated that cyclins and cyclin-dependent kinases that determine cell cycle progression are involved in beta cell replication, and more recently, menin in association with cyclin-dependent kinase...... inhibitors has been demonstrated to be important in beta cell growth. In this review, we consider and highlight some aspects of cell cycle regulation in relation to beta cell replication. The role of cell cycle regulation in beta cell replication is mostly from studies in rodent models, but whether...

  13. Curious terminal turn of rolling rings

    CERN Document Server

    Jalali, Mir Abbas; Alam, Reza

    2014-01-01

    We report an unexpected reverse spiral turn in the final stage of the motion of rolling rings. It is well known that spinning disks have definite centers of rotation until they stop. While a spinning ring starts its motion with a similar kinematics, moving along a cycloidal path prograde with the direction of its rigid body rotation, the mean trajectory of its center of mass develops an inflection point so that the ring makes a spiral turn and revolves in a retrograde direction around a new center. Using high speed imaging and numerical simulations of models featuring a rolling rigid body, we show that the hollow geometry of a ring tunes the rotational air drag resistance so that the frictional force at the contact point with the ground changes its direction at the inflection point and puts the ring on a retrograde spiral trajectory. Our findings have potential applications in designing topologically new surface-effect flying objects capable of performing complex reorientation and translational maneuvers.

  14. Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas

    DEFF Research Database (Denmark)

    Wewer, U M; Gerecke, D R; Durkin, M E

    1994-01-01

    Overlapping cDNA clones that encode the full-length human laminin beta 2 chain, formerly called the S chain, were isolated. The cDNA of 5680 nt contains a 5391-nt open reading frame encoding 1797 amino acids. At the amino terminus is a 32-amino-acid signal peptide that is followed by the mature...... beta 2 chain polypeptide of 1765 amino acids with a calculated molecular mass of 192,389 Da. The human beta 2 chain is predicted to have all of the seven structural domains typical of the beta chains of laminin, including the short cysteine-rich alpha region. The amino acid sequence of human beta 2...... chain showed 86.1% sequence identity to the rat beta 2 chain, 50.0% to the human beta 1 chain, and 36.3% to the human beta 3 chain. The greatest sequence identity was in domains VI, V, and III. The sequence of a 24-amino-acid peptide fragment isolated from the beta 2 chain of laminin purified from human...

  15. LHCb: $2\\beta_s$ measurement at LHCb

    CERN Multimedia

    Conti, G

    2009-01-01

    A measurement of $2\\beta_s$, the phase of the $B_s-\\bar{B_s}$ oscillation amplitude with respect to that of the ${\\rm b} \\rightarrow {\\rm c^{+}}{\\rm W^{-}}$ tree decay amplitude, is one of the key goals of the LHCb experiment with first data. In the Standard Model (SM), $2\\beta_s$ is predicted to be $0.0360^{+0.0020}_{-0.0016} \\rm rad$. The current constraints from the Tevatron are: $2\\beta_{s}\\in[0.32 ; 2.82]$ at 68$\\%$CL from the CDF experiment and $2\\beta_{s}=0.57^{+0.24}_{-0.30}$ from the D$\\oslash$ experiment. Although the statistical uncertainties are large, these results hint at the possible contribution of New Physics in the $B_s-\\bar{B_s}$ box diagram. After one year of data taking at LHCb at an average luminosity of $\\mathcal{L}\\sim2\\cdot10^{32}\\rm cm^{-2} \\rm s^{-1}$ (integrated luminosity $\\mathcal{L}_{\\rm int}\\sim 2 \\rm fb^{-1}$), the expected statistical uncertainty on the measurement is $\\sigma(2\\beta_s)\\simeq 0.03$. This uncertainty is similar to the $2\\beta_s$ value predicted by the SM.

  16. Characterization of the effect of Cr(VI) on humoral innate immunity using Drosophila melanogaster.

    Science.gov (United States)

    Pragya, P; Shukla, A K; Murthy, R C; Abdin, M Z; Kar Chowdhuri, D

    2015-11-01

    With the advancement of human race, different anthropogenic activities have heaped the environment with chemicals that can cause alteration in the immune system of exposed organism. As a first line of barrier, the evolutionary conserved innate immunity is crucial for the health of an organism. However, there is paucity of information regarding in vivo assessment of the effect of environmental chemicals on innate immunity. Therefore, we examined the effect of a widely used environmental chemical, Cr(VI), on humoral innate immune response using Drosophila melanogaster. The adverse effect of Cr(VI) on host humoral response was characterized by decreased gene expression of antimicrobial peptides (AMPs) in the exposed organism. Concurrently, a significantly decreased transcription of humoral pathway receptors (Toll and PGRP) and triglyceride level along with inhibition of antioxidant enzyme activities were observed in exposed organism. This in turn weakened the immune response of exposed organism that was manifested by their reduced resistance against bacterial infection. In addition, overexpression of the components of humoral immunity particularly Diptericin benefits Drosophila from Cr(VI)-induced humoral immune-suppressive effect. To our knowledge, this is the first report regarding negative impact of an environmental chemical on humoral innate immune response of Drosophila along with subsequent protection by AMPs, which may provide novel insight into host-chemical interactions. Also, our data validate the utility and sensitivity of Drosophila as a model that could be used for screening the possible risk of environmental chemicals on innate immunity with minimum ethical concern that can be further extrapolated to higher organisms. © 2014 Wiley Periodicals, Inc.

  17. ββ- and γγ-turns in proteins revisited: A new set of amino acid turn ...

    Indian Academy of Sciences (India)

    The number of β-turns in a representative set of 426 protein three-dimensional crystal structures selected from the re- cent Protein Data Bank has nearly doubled and the number of γ-turns in a representative set of 320 proteins has in- creased over seven times since the previous analysis. β-turns (7153) and γ-turns (911) ...

  18. Cinética e equilíbrio de adsorção dos oxiânions Cr (VI, Mo (VI e Se (VI pelo sal de amônio quaternário de quitosana Kinetics and equilibrium of adsorption of oxyanions Cr (VI, Mo (VI and Se (VI by quaternary ammonium chitosan salt

    Directory of Open Access Journals (Sweden)

    Viviane A. Spinelli

    2005-07-01

    Full Text Available O sal quaternário de quitosana foi sintetizado com cloreto de glicidil trimetil amônio. A modificação química foi caracterizada por espectrometria no IV, RMN de 13C e ¹H, e mmol/g de grupos quaternários presentes na matriz polimérica por condutimetria. A remoção de Cr (VI, Mo (VI e Se (VI, em meio aquoso, foi investigada em processo de batelada. A adsorção mostrou ser dependente do pH para o Cr (VI e Se (VI, com um pH ótimo de adsorção, entre 4,0 a 6,0. Para o Mo (VI a adsorção manteve-se quase constante no intervalo de pH entre 4,0 e 11,5. O modelo de isoterma de Langmuir descreveu melhor os dados de equilíbrio na faixa de concentração investigada. No presente estudo, um grama do sal quaternário de quitosana reticulado com glutaraldeído adsorveu 68,3 mg de Cr, 63,4 mg de Mo e 90,0 mg de Se. A velocidade de adsorção, no processo, segue a equação cinética de pseudo segunda-ordem, sendo que o equilíbrio para os três íons foi alcançado próximo aos 200 minutos. A análise dispersiva de raios-X para o Cr (VI mostrou que o principal mecanismo de adsorção é a troca iônica entre os íons Cl- da superfície do polímero pelos oxiânions. O trocador aniônico apresentou a seguinte ordem de seletividade: Cr (VI > Mo (VI > Se (VI.Quaternary chitosan salt was synthesized in the presence of glycidyl trimetyl ammonium chloride. The polymer was characterized by spectroscopic techniques: infrared, 13C and ¹H NMR, while the amount of quaternary ammonium groups was obtained by condutimetry. The removal of Cr (VI, Mo (VI and Se (VI from aqueous solutions was carried out in batch adsorption processes. The process seemed to be pH dependent for Cr (VI and Se (VI with an optimum pH ranging from 4.0 to 6.0; while for Mo (VI the adsorption remained almost constant within the range between 4.0 and 11.5. The Langmuir isotherm model provided the best fit of the equilibrium data over the whole concentration investigated. In the experiment

  19. PREFACE: VI Mexican School on Gravitation and Mathematical Physics

    Science.gov (United States)

    Alcubierre, Miguel; Cervantes-Cota, Jorge L.; Montesinos, Merced

    2005-01-01

    The Mexican School on Gravitation and Mathematical Physics, sponsored by the Mexican Physical Society, started in the early 1990s. The aim of the school is to consider different topics at the frontiers of current research on gravitation, field theory and mathematical physics. It is held every two years and a different theme is chosen on each occasion. The school, which is oriented towards advanced graduate students and non-expert researchers, has been gaining reputation because of the quality of the lectures given by leaders in each field. On previous occasions, the subjects covered have been Supergravity and Mathematical Physics, Branes, Black Holes, Early Universe and Observational Cosmology, and the speakers have included A. Ashtekar, A. Balachandran, J. Barrow, B. Carter, P. Chrusciel, G. Gibbons, M. Heusler, W. Israel, F. Müller-Hoisen, R. Kallosh, A. Linde, Y. Neeman, R. Myers, A. Peet, L. Randall, C. Rovelli, L. Smolin, R. Sorkin, P. Van Niewenhuizen, R. Wald, among other top ranked physicists. Let us now turn our attention to the current edition of the school. The two great pillars of twentieth century physics are quantum mechanics and the general theory of relativity (GR) and, in spite of their great independent successes, it has been enormously difficult to combine them into a single theoretical framework. It seems that the nonlinearities of GR and its attractive nature pose severe problems to understand its possible quantum nature, e.g. renormalization issues. In order to solve this and other quantization problems, as well as to try to unify gravity with the other quantum fields (electromagnetic, weak, and strong fields), in the past decades several different approaches to quantum gravity have been developed. In view of the fundamental importance of such topics today, the theme Approaches to Quantum Gravity was chosen for the VI Mexican School on Gravitation and Mathematical Physics. We considered that subjects like loop quantum gravity (quantum

  20. Vi behøver innovation

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2007-01-01

    . Især hvad angår vores forbrugsmønstre. Her er der behov for at kongeriget Danmark med sine 13 ton CO2-emission pr. person om året lytter. I landet hvor kraftvarmeproduk­tion, vindturbiner og industrial ecology i form af Kalundborg eksperimentet blev født, bør vi ikke også ride på denne nye miljøbølge......? Den amerikanske videnskabsmand Jeremy Rifkin beskriver i sin seneste bog, The European Dream, hvordan europæisk energipolitik, -forskning, -udvikling og relateret industri kan hjælpe os til at bremse vores for øjeblikket eksponentielt stigende CO2-produktion - og hvordan vores globaliseringstankegang...... rent faktisk kan fremme denne indsats. Den eneste udfordring er, at nogen skal igangsætte en økonomisk/industriel revolution, for at drømmen går i opfyldelse. Hvem skal tage ansvar for at sætte denne revolution i gang, og hvordan skal den opnås? Rifkin's patentløsning er inspirerende. Den er kort...

  1. [VI Symposium on "Chemistry of Proteolytic Enzymes"].

    Science.gov (United States)

    Rumsh, L D; Rotanova, T V

    2008-01-01

    The VI Symposium on the Chemistry of Proteolytic Enzymes took place in Moscow on April 23-25, 2007. It was dedicated to the memory of Corresponding Member of the Russian Academy of Sciences Vladimir Konstantinovich Antonov. At the symposium, 40 reports were delivered and 103 posters were presented in the following sections: (1) expression of genes, isolation and general characterization of proteases; (2) structure-function studies of proteases; (3) regulation of the activity of proteolytic enzymes; (4) regulatory functions of proteolytic enzymes; (5) proteases in biotechnology, protein engineering, and peptide synthesis; and (6) proteolysis and medicine. In addition to Russian scientists, researchers from the United States, the Netherlands, France, Ukraine, Belarus, Azerbaijan and Uzbekistan took part in the work of the symposium. Note that, in the five years since the V Symposium, the geography of Russian scientific centers working in the area of proteolysis has been considerably extended. Participating in the forum were researchers from, Novosibirsk, Tomsk, Penza, and Stavropol in addition to scientists from Moscow, Saint Petersburg, Petrozavodsk, Kazan, Nizhni Novgorod, and Krasnodar.

  2. Wind tunnel test of musi VI bridge

    Science.gov (United States)

    Permata, Robby; Andika, Matza Gusto; Syariefatunnisa, Risdhiawan, Eri; Hermawan, Budi; Noordiana, Indra

    2017-11-01

    Musi VI Bridge is planned to cross the Musi River in Palembang City, South Sumatera Province, Indonesia. The main span is a steel arch type with 200 m length and side span length is 75 m. Finite element analysis results showed that the bridge has frequency ratio for torsional and heaving mode (torsional frequency/heaving frequency)=1.14. This close to unity value rises concern about aerodynamic behaviour and stability of the bridge deck under wind loading. Sectional static and free vibration wind tunnel test were performed to clarify this phenomena in B2TA3 facility in Serpong, Indonesia. The test followed the draft of Guide of Wind Tunnel Test for Bridges developed by Indonesian Ministry of Public Works. Results from wind tunnel testing show that the bridge is safe from flutter instability and no coupled motion vibration observed. Therefore, low value of frequency ratio has no effect to aerodynamic behaviour of the bridge deck. Vortex-induced vibration in heaving mode occurred in relatively low wind velocity with permissible maximum amplitude value.

  3. MEDIACRACY TURNS INTO A SYNONYM OF MEDIOCRITY?

    Directory of Open Access Journals (Sweden)

    Valentina CHIPER

    2014-11-01

    Full Text Available The link between freedom of speech and democracy is based on ideological legitimacy report. A new phenomenon which is worth noticing is the conversion of the freedom of expression from a freedom seen in certain aspects as a solitary freedom into a communication of the masses. Another challenge is prompted by the change of the traditional communication system at the dawn of technology, Internet and its various applications, as well as of the channels used. A weak point is the change in the values scale. If a journalist or a book is deemed good or valuable in terms of competence and ideas, these values are now unfortunately inspired by what we watch on TV. In this train of thoughts, reliable opinion leaders are no longer the same. Mediacracy turns into a synonym of mediocrity with affectivity and emotion prevailing over reason and instead of the communication of thoughts and opinions.

  4. Turned Back: Mad Men as Intermedial Melodrama

    Directory of Open Access Journals (Sweden)

    Monique Rooney

    2012-09-01

    Full Text Available This essay draws on definitions of gesture (Giorgio Agamben and Peter Brooks and catachresis (Peter Brooks, Jacques Derrida to examine the primacy of non-verbal signifiers as communicators of meaning in AMC’s Mad Men. Beginning with an analysis of Mad Men’s credit sequence, it draws attention to Mad Men’s use of gesture and catachresis in relation to melodrama’s privileging of non-verbal and naturalistic expression and its persistence as an intermedial mode that has moved back and forth between various media (theatre, novel, cinema, television and now digital formats. It argues that Mad Men’s melodramatic aesthetic is one that obliquely, and via a gestural and rhetorical ‘turned back’, communicates its relation to the past and the present.

  5. Turning Video Resource Management into Cloud Computing

    Directory of Open Access Journals (Sweden)

    Weili Kou

    2016-07-01

    Full Text Available Big data makes cloud computing more and more popular in various fields. Video resources are very useful and important to education, security monitoring, and so on. However, issues of their huge volumes, complex data types, inefficient processing performance, weak security, and long times for loading pose challenges in video resource management. The Hadoop Distributed File System (HDFS is an open-source framework, which can provide cloud-based platforms and presents an opportunity for solving these problems. This paper presents video resource management architecture based on HDFS to provide a uniform framework and a five-layer model for standardizing the current various algorithms and applications. The architecture, basic model, and key algorithms are designed for turning video resources into a cloud computing environment. The design was tested by establishing a simulation system prototype.

  6. Turning assistive machines into assistive robots

    Science.gov (United States)

    Argall, Brenna D.

    2015-01-01

    For decades, the potential for automation in particular, in the form of smart wheelchairs to aid those with motor, or cognitive, impairments has been recognized. It is a paradox that often the more severe a person's motor impairment, the more challenging it is for them to operate the very assistive machines which might enhance their quality of life. A primary aim of my lab is to address this confound by incorporating robotics autonomy and intelligence into assistive machines turning the machine into a kind of robot, and offloading some of the control burden from the user. Robots already synthetically sense, act in and reason about the world, and these technologies can be leveraged to help bridge the gap left by sensory, motor or cognitive impairments in the users of assistive machines. This paper overviews some of the ongoing projects in my lab, which strives to advance human ability through robotics autonomy.

  7. Introduction: The Participatory Turn in Urbanism

    Directory of Open Access Journals (Sweden)

    Maroš Krivý

    2014-08-01

    Full Text Available This issue of Footprint examines the recent participatory turn in urban planning and urban design. It discusses the co-opting of participatory processes by planning departments, the systematic disregard of inequalities, and the empowering of the market resulting from the ‘anti-statism’ present in many participatory schemes.What is the relationship between the institutionalisation of participation and the practices of autonomy, self-organisation, and inclusion? When and how does genuine empowerment of collectives take place? Does the demand for the empowerment of local organisations and communities strengthen the market forces at the expense of central government?This issue attempts to problematise ‘participation’, to call attentions to some of its shortcomings, deficits, and limitations, not in order to necessarily bypass the demand for the democratisation of the urban, but in order to rectify and strengthen it.

  8. Pharmacologic differences between beta blockers.

    Science.gov (United States)

    Wood, A J

    1984-10-01

    All of the beta blockers act by antagonizing the actions of the endogenous adrenergic agonists epinephrine and norepinephrine at the beta-adrenergic receptors. However, a number of pharmacologic differences exist between the various agents. Some drugs, such as atenolol and metoprolol, are relatively selective for the beta-1-adrenergic receptors, requiring higher concentrations to block beta-2-adrenergic receptors than are required to block beta-1 receptors. It should be noted, however, that these selective beta blockers all block beta-2 receptors when their concentrations are high enough. When patients with asthma must receive a beta blocker, low doses of a selective drug should be used. Recent studies, however, have suggested that the use of a nonselective beta blocker may be desirable to antagonize some beta-2-mediated metabolic effects, such as hypokalemia, induced by epinephrine. Pindolol is the only beta-receptor antagonist available in the United States with intrinsic sympathomimetic, or partial agonist, activity. Such drugs, because of their partial agonist activity, cause some sympathetic stimulation under conditions of low endogenous sympathetic tone, such as while subjects are at rest in the supine position. Under conditions of higher sympathetic tone, pindolol blocks the effects of the endogenous agonists, producing the characteristic effects of a beta blocker. Membrane-stabilizing activity was first recognized with propranolol, and the value of this property has been a source of controversy ever since, but recent studies suggest that propranolol may induce electrophysiologic effects by mechanisms other than beta blockade. Pharmacokinetic differences between the drugs are also of importance.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. A Case of Aplasia Cutis Congenita Type VI: Bart Syndrome

    National Research Council Canada - National Science Library

    Yasmin Alfayez; Sahar Alsharif; Adel Santli

    2017-01-01

    Aplasia cutis congenita type VI, also known as Bart syndrome, is a rare genetic mechanobullous disorder characterized by congenital localized absence of skin, mucocutaneous blistering lesions, and nail abnormalities...

  10. Stark broadening parameter tables for F VI and Cl VII

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    1998-01-01

    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 2 F VI and 10 Cl VII multiplets as a function of temperature and perturber density.

  11. ALTERATION OF U(VI)-PHASES UNDER OXIDIZING CONDITIONS

    Energy Technology Data Exchange (ETDEWEB)

    A.P. Deditius; S. Utsunomiya; R.C. Ewing

    2006-02-21

    Uranium-(VI) phases are the primary alteration products of the UO{sub 2} in spent nuclear fuel and the UO{sub 2+x}, in natural uranium deposits. The U(VI)-phases generally form sheet structures of edge-sharing UO{sub 2}{sup 2+} polyhedra. The complexity of these structures offers numerous possibilities for coupled-substitutions of trace metals and radionuclides. The incorporation of radionuclides into U(VI)-structures provides a potential barrier to their release and transport in a geologic repository that experiences oxidizing conditions. In this study, we have used natural samples of UO{sub 2+x}, to study the U(VI)-phases that form during alteration and to determine the fate of the associated trace elements.

  12. Expression and distribution of type VI collagen in gynecomastia.

    Science.gov (United States)

    Lanzafame, S; Magro, G; Colombatti, A

    1994-06-01

    We investigated the distribution of type VI collagen in 36 cases of routinely fixed and paraffin-embedded gynecomastia using an immunoperoxidase method for light microscopic visualization. Four samples of normal male mammary gland tissue were also included as controls. A protease predigestion was essential for the visualization of this extracellular matrix (ECM) glycoprotein. In normal male breast, no immunoreaction for type VI collagen was detected in the stroma surrounding the ducts. Gynecomastia was classified into three histological types: florid (type I), fibrous (type II), and intermediate (type III). Type VI collagen was differentially expressed in the periductal stroma of all types. This collagen was markedly expressed at the early disease stage (type I) when the periductal stroma is highly cellular and vascular. Its expression decreased when periductal stroma undergoing fibrotic transformation (type III) and completely disappeared from the dense periductal stroma of fibrous stage (type II). These findings suggest that type VI collagen is involved in the ECM remodelling occurring in gynecomastia.

  13. INTELSAT VI artist concept drawing titled 'Ocean Bridge'

    Science.gov (United States)

    1992-01-01

    International Telecommunications Satellite Organization (INTELSAT) VI artist concept drawing titled 'Ocean Bridge' shows satellite built by Hughes Aircraft Company and owned and operated by INTELSAT, a 122-nation cooperative, orbiting the Earth.

  14. Mechanism of uranium (VI) removal by two anaerobic bacterial communities

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Monica [Centro de Ciencias do Mar, Universidade do Algarve, FCT-DQF (edificio 8), Campus de Gambelas, 8005-139 Faro (Portugal); Faleiro, Maria Leonor [IBB - Centro de Biomedicina Molecular e Estrutural, Universidade do Algarve, FCT, Campus de Gambelas, 8005-139 Faro (Portugal); Costa, Ana M. Rosa da [Centro de Investigacao em Quimica do Algarve, Universidade do Algarve, FCT, DQF, Campus de Gambelas, 8005-139 Faro (Portugal); Chaves, Sandra; Tenreiro, Rogerio [Universidade de Lisboa, Faculdade de Ciencias, Centro de Biodiversidade, Genomica Integrativa e Funcional (BioFIG), Campus de FCUL, Campo Grande, 1749-016 Lisboa (Portugal); Matos, Antonio Pedro [Servico de Anatomia Patologica, Hospital Curry Cabral, Lisboa (Portugal); Costa, Maria Clara, E-mail: mcorada@ualg.pt [Centro de Ciencias do Mar, Universidade do Algarve, FCT-DQF (edificio 8), Campus de Gambelas, 8005-139 Faro (Portugal)

    2010-12-15

    The mechanism of uranium (VI) removal by two anaerobic bacterial consortia, recovered from an uncontaminated site (consortium A) and other from an uranium mine (consortium U), was investigated. The highest efficiency of U (VI) removal by both consortia (97%) occurred at room temperature and at pH 7.2. Furthermore, it was found that U (VI) removal by consortium A occurred by enzymatic reduction and bioaccumulation, while the enzymatic process was the only mechanism involved in metal removal by consortium U. FTIR analysis suggested that after U (VI) reduction, U (IV) could be bound to carboxyl, phosphate and amide groups of bacterial cells. Phylogenetic analysis of 16S rRNA showed that community A was mainly composed by bacteria closely related to Sporotalea genus and Rhodocyclaceae family, while community U was mainly composed by bacteria related to Clostridium genus and Rhodocyclaceae family.

  15. Thermodynamical analysis of the fission product release in the ORNL VI-3 and VI-5 tests; Analyse thermodynamique du relachement des produits de fission dans les essais ORNL VI-3 et VI-5

    Energy Technology Data Exchange (ETDEWEB)

    Defoort, J.; Froment, K

    1998-06-01

    The thermodynamical equilibrium hypothesis has been applied to the tests ORNL (Oak Ridge National Laboratory) VI-3 and VI-5 (Vertical Induction heated), to study fission release products. Irradiated fuel samples were heated under oxidizing (VI-3) and reducing (VI-5) controlled atmosphere. They can be compared to the Vercors 4 and 5 tests. The thermodynamical calculus results of barium and ruthenium fission products release, agree in the lump with measures, whatever the gas phase nature. The strontium release calculus under reducing atmosphere, is largely upper than those measured and correctly evaluated under oxidizing atmosphere. These results confirm those obtained for Vercors 4 and 5 and show the interest of the select model. (A.L.B.)

  16. VI Congrés Internacional de Conflictologia

    OpenAIRE

    Planell Estany, Josep A.

    2013-01-01

    Discurs del rector de la Universitat Oberta de Catalunya, Josep A. Planell Estany, amb motiu del VI Congrés Internacional de Conflictologia. Discurso del rector de la Universitat Oberta de Catalunya, Josep A. Planell Estany, con motivo del VI Congreso Internacional de Conflictología. Speech by the president of the Universitat Oberta de Catalunya, Josep A. Planell Estany,on the occasion of the Sixth International Congress on Conflict Resolution.

  17. Observation of the Double Beta Decay of ^48Ca^*

    Science.gov (United States)

    Piepke, Andreas

    1996-10-01

    Neutrino-less double beta decay is at present the most sensitive kinematic test for finite neutrino mass. The unfolding of a neutrino mass (or a mass limit) from measured decay rates, however, relies on complicated nuclear structure calculations. In the absence of any rigorous test for these calculations the investigation of the very rare two-neutrino double beta decay (β β 2ν) decay serves to verify the validity of the nuclear models. Among all candidate nuclei the double beta decay ^48Caarrow ^48Ti is unique, since it is the only one which can be treated ``exactly'' in the nuclear shell model. Taking advantage of this special situation, isotopically enriched ^48Ca (enrichment 73% ), in form of finely powdered CaCO_3, was exposed in the Irvine time projection chamber located at the Hoover dam, 72 m below ground. The ongoing data analysis shows strong evidence for the presence of a β β 2ν signal i.e. a two electron spectrum with the expected endpoint of 4.3 MeV. The experimental half life appears to agree with most shell model calculations. A detailed discussion of the results will be presented.(Work in collaboration with A. Balysh, V.I. Lebedev, A. Pronsky, KIAE Moscow, A. De Silva, M.K. Moe, M.A. Nelson, M.A. Vient, UC Irvine and K. Lou, P. Vogel, Caltech.) ^* Supported by U.S. Department of Energy. A.P. acknowledges support of the Alexander von Humboldt Foundation.

  18. Complexation of Gluconate with Uranium(VI) in Acidic Solutions: Thermodynamic Study with Structural Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zhicheng; Helms, G.; Clark, S. B.; Tian, Guoxin; Zanonato, PierLuigi; Rao, Linfeng

    2009-01-05

    Within the pC{sub H} range of 2.5 to 4.2, gluconate forms three uranyl complexes UO{sub 2}(GH{sub 4}){sup +}, UO{sub 2}(GH{sub 3})(aq), and UO{sub 2}(GH{sub 3})(GH{sub 4}){sup -}, through the following reactions: (1) UO{sub 2}{sup 2+} + GH{sub 4}{sup -} = UO{sub 2}(GH{sub 4}){sup +}, (2) UO{sub 2}{sup 2+} + GH{sub 4}{sup -} = UO{sub 2}(GH{sub 3})(aq) + H{sup +}, and (3) UO{sub 2}{sup 2+} + 2GH{sub 4}{sup -} = UO{sub 2}(GH{sub 3})(GH{sub 4}){sup -} + H{sup +}. Complexes were inferred from potentiometric, calorimetric, NMR, and EXAFS studies. Correspondingly, the stability constants and enthalpies were determined to be log {Beta}{sub 1} = 2.2 {+-} 0.3 and {Delta}H{sub 1} = 7.5 {+-} 1.3 kJ mol{sup -1} for reaction (1), log {Beta}{sub 2} = -(0.38 {+-} 0.05) and {Delta}H{sub 2} = 15.4 {+-} 0.3 kJ mol{sup -1} for reaction (2), and log {Beta}{sub 3} = 1.3 {+-} 0.2 and {Delta}H{sub 3} = 14.6 {+-} 0.3 kJ mol{sup -1} for reaction (3), at I = 1.0 M NaClO{sub 4} and t = 25 C. The UO{sub 2}(GH{sub 4}){sup +} complex forms through the bidentate carboxylate binding to U(VI). In the UO{sub 2}(GH{sub 3})(aq) complex, hydroxyl-deprotonated gluconate (GH{sub 3}{sup 2-}) coordinates to U(VI) through the five-membered ring chelation. For the UO{sub 2}(GH{sub 3})(GH{sub 4}){sup -} complex, multiple coordination modes are suggested. These results are discussed in the context of trivalent and pentavalent actinide complexation by gluconate.

  19. [Beta-blocker intoxication].

    Science.gov (United States)

    Joye, F

    2000-05-20

    Beta-blocker intoxication is not frequent but can produce particularly severe or fatal conditions which must not be underestimated. Severity of beta-blocker intoxication varies from one compound to another. The more toxic drugs are propranolol, sotalol, oxprenolol, metoprolol, atenolol, acebutolol, labetalol, and carvedilol. Besides the drug type, history taking can provide a precise assessment of risk, particularly important in when elderly patients with a cardiovascular history have taken more than 20 tablets, when emergency care is provided late, and when other cardiotoxic or psychotoxic drugs have been coingested. The diagnosis of beta-blocker intoxication must be suspected in any case associating hypotension and bradycardia. The main cardiovascular complications are cardiogenic shock, atrio-ventricular conduction disorders, and obviously life-threatening ventricular arrhythmia with cardiac arrest. Centrally induced respiratory arrest is a rare but dreadful consequence which can occur suddenly even without hemodynamic failure. Neurologic toxicity is mainly expressed by consciousness disorders and more sporadically by seizures. Laboratory tests show variable serum potassium, lactic acidosis, hypoxia-hypercapnia resulting from hypoventilation, and rarely hypoglycemia. The ECG should be recorded early because electrocardiographic signs usually appear before clinical signs and QRS enlargement is a factor predictive of severe ventricular arrhythmia. The patient must be placed in an intensive care unit for continuous multiparametric monitoring. Besides gastric evacuation and symptomatic measures, treatment essentially requires glucagon for its positive inotropic effect after high intravenous doses. If glucagon infusion is ineffective or unavailable, an alternative would be to use high doses of vasoactive agents, choosing isoproterenol or epinephrine as the first intention drugs.

  20. Role of metal d states in II-VI semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Wei, S.; Zunger, A.

    1988-05-15

    All-electron band-structure calculations and photoemission experiments on II-VI semiconductors both exhibit a metal d subband inside the main valence band. It has nevertheless been customary in pseudopotential and tight-binding approaches to neglect the metal d band by choosing Hamiltonian parameters which place this band inside the chemically inert atomic cores. Using all-electron self-consistent electronic-structure techniques (which treat the outermost d electrons on the same footing as other valence electrons) and comparing the results to those obtained by methods which remove the d band from the valence spectrum, we study their effects on valence properties. For II-VI semiconductors we find that p-d repulsion and hybridization (i) lower the band gaps, (ii) reduce the cohesive energy, (iii) increase the equilibrium lattice parameters, (iv) reduce the spin-orbit splitting, (v) alter the sign of the crystal-field splitting, (vi) increase the valence-band offset between common-anion II-VI semiconductors, and (vii) modify the charge distributions of various II-VI systems and their alloys. p-d repulsion is also shown to be responsible for the occurrence of deep Cu acceptor levels in II-VI semiconductors (compared with shallow acceptors of Zn in III-V), for the anomalously small band gaps in chalcopyrites, and for the negative exchange splitting in ferromagnetic MnTe.

  1. Beating the Heat: Fast Scanning Melts Beta Sheet Crystals

    Science.gov (United States)

    Cebe, Peggy; Hu, Xiao; Kaplan, David; Zhuravlev, Evgeny; Wurm, Andreas; Arbeiter, Daniella; Schick, Christoph

    2014-03-01

    Beta-pleated-sheet crystals are among the most stable of protein secondary structures, and are responsible for the remarkable physical properties of many fibrous proteins, such as silk. Previous thinking was that beta-pleated-sheet crystals in the dry solid state would not melt upon input of heat energy alone. Indeed, at conventional heating rates (~1-50 °C/min), silk exhibits its glass transition (~175 °C), followed by cold crystallization, and then by immediate thermal degradation beginning at about 225 °C. Here we demonstrate that beta-pleated-sheet crystals can melt directly from the solid state to become random coils, helices, and turns. We use fast scanning chip calorimetry at 2,000 K/s to avoid thermal degradation, and report the first reversible thermal melting of protein beta-pleated-sheet crystals, exemplified by silk fibroin. The similarity between thermal melting behavior of lamellar crystals of synthetic polymers and beta-pleated-sheet crystals is confirmed. The authors acknowledge support from the National Science Foundation and German Academic Exchange Service DAAD; EZ acknowledges a European Union funded Marie Curie EST fellowship (ADVATEC); XH and DK acknowledge NIH P41 Tissue Engineering Resource Center.

  2. Turn me on! Using the “Internet of Things” to turn things on and off

    CSIR Research Space (South Africa)

    Butgereit, L

    2011-10-01

    Full Text Available to the Internet. There are many examples of things posting their status on Twitter and allowing uni-directional access. TurnMeOn is an example of allowing bidirectional access between people and things using Internet protocols. Users can query the status of a...

  3. Why Critical Literacy Should Turn to "The Affective Turn": Making a Case for Critical Affective Literacy

    Science.gov (United States)

    Anwaruddin, Sardar M.

    2016-01-01

    The central argument of this essay is that critical literacy with a rationalistic bent may not enable us to cope with ethical dilemmas in our responsiveness to human sufferings. I argue that critical literacy education would benefit from turning to the recent scholarship on affect/emotion studies. I draw upon the works of Sara Ahmed--one of the…

  4. Assessing lexical, syntactic, and conceptual turn-by-turn alignment in conversations involving conflict and deception

    DEFF Research Database (Denmark)

    Duran, Nicholas; Fusaroli, Riccardo; Paxton, Alexandra

    2015-01-01

    -based NLP tools, the procedure begins by taking conversational partners' turns and converting each into a lemmatized sequence of words, assigning part-of-speech tags and computing high-dimensional semantic vectors per each utterance. Words and part-of-speech tags are further sequenced into n-g! rams...

  5. Vi har intet lært - hvornår lærer vi det?

    DEFF Research Database (Denmark)

    Sodemann, Morten

    2016-01-01

    WHO anså fra i går ikke længere ebola for at være en trussel mod global folkesundhed, så fra i dag er kameraerne slukket i Vestafrika og vi er tilbage hvor vi startede. SDG målene skal have et dansk udtryk, men hvad er de danske kompetencer på globalt plan når sundhed ikke længere er en kerneakti......WHO anså fra i går ikke længere ebola for at være en trussel mod global folkesundhed, så fra i dag er kameraerne slukket i Vestafrika og vi er tilbage hvor vi startede. SDG målene skal have et dansk udtryk, men hvad er de danske kompetencer på globalt plan når sundhed ikke længere er en...

  6. Conditional Betas and Investor Uncertainty

    OpenAIRE

    Fernando D. Chague

    2013-01-01

    We derive theoretical expressions for market betas from a rational expectation equilibrium model where the representative investor does not observe if the economy is in a recession or an expansion. Market betas in this economy are time-varying and related to investor uncertainty about the state of the economy. The dynamics of betas will also vary across assets according to the assets' cash-flow structure. In a calibration exercise, we show that value and growth firms have cash-flow structures...

  7. ACCOUNTING INFORMATION AND MARKET BETA

    OpenAIRE

    Amorim, Ana Luísa Gambi Cavallari; Lima, Iran Siqueira; Pimenta Junior,Tabajara

    2014-01-01

    The efficient market hypothesis and various models of asset pricing brought the concept of the new relevant information has an immediate effect on the price of a security by changing expectations about their risk: market beta. The accounting numbers seem to exhibit a relationship with the market risk of firms and thus can provide a supplementary estimate to help reduce the error of estimation of market betas. This work was to investigate whether the accounting betas have a business relationsh...

  8. Adsorption and Diffusion of Xylene Isomers on Mesoporous Beta Zeolite

    Directory of Open Access Journals (Sweden)

    Aixia Song

    2015-12-01

    Full Text Available A systematic and detailed analysis of adsorption and diffusion properties of xylene isomers over Beta zeolites with different mesoporosity was conducted. Adsorption isotherms of xylene isomers over microporous and mesoporous Beta zeolites through gravimetric methods were applied to investigate the impact of mesopores inside Beta zeolites on the adsorption properties of xylene isomers in the pressure range of lower 20 mbar. It is seen that the adsorption isotherms of three xylene isomers over microporous and mesoporous Beta zeolites could be successfully described by the single-site Toth model and the dual-site Toth model, respectively. The enhanced adsorption capacities and decreased Henry’s constants (KH and the initial heats of adsorption (Qst for the all xylene isomers are observed after the introduction of mesopores in the zeolites. For three xylene isomers, the order of Henry’s constant is o-xylene > m-xylene > p-xylene, whereas the adsorption capacities of Beta zeolite samples for xylene isomers execute the following order of o-xylene > p-xylene > m-xylene, due to the comprehensive effects from the molecular configuration and electrostatic interaction. At the same time, the diffusion properties of xylene isomers in the mesoporous Beta zeolites were also studied through the desorption curves measured by the zero length column (ZLC method at 333–373 K. It turned out that the effective diffusion time constant (Deff/R2 is a growing trend with the increasing mesoporosity, whereas the tendency of the activation energy is just the reverse, indicating the contribution of mesopores to facilitate molecule diffusion by shortening diffusion paths and reducing diffusion resistances. Moreover, the diffusivities of three xylene isomers in all Beta zeolites follow an order of p-xylene > m-xylene > o-xylene as opposed to KH, conforming the significant effects of adsorbate-adsorbent interaction on the diffusion.

  9. Supersymmetry Inspired QCD Beta Function

    CERN Document Server

    Ryttov, Thomas A

    2008-01-01

    We propose an all orders beta function for ordinary Yang-Mills theories with or without fermions inspired by the Novikov-Shifman-Vainshtein-Zakharov beta function of N=1 supersymmetric gauge theories. The beta function allows us to bound the conformal window. When restricting to one adjoint Weyl fermion we show how the proposed beta function matches the one of supersymmetric Yang-Mills theory. The running of the pure Yang-Mills coupling is computed and the deviation from the two loop result is presented. We then compare the deviation with the one obtained from lattice data also with respect to the two loop running.

  10. Supersymmetry Inspired QCD Beta Function

    DEFF Research Database (Denmark)

    Ryttov, Thomas; Sannino, Francesco

    2008-01-01

    We propose an all orders beta function for ordinary Yang-Mills theories with or without fermions inspired by the Novikov-Shifman-Vainshtein-Zakharov beta function of N=1 supersymmetric gauge theories. The beta function allows us to bound the conformal window. When restricting to one adjoint Weyl...... fermion we show how the proposed beta function matches the one of supersymmetric Yang-Mills theory. The running of the pure Yang-Mills coupling is computed and the deviation from the two loop result is presented. We then compare the deviation with the one obtained from lattice data also with respect...

  11. Formaldehyde removal from wastewater and air by using UV, ferrate(VI) and UV/ferrate(VI).

    Science.gov (United States)

    Talaiekhozani, Amirreza; Salari, Malihe; Talaei, Mohammad Reza; Bagheri, Marzieh; Eskandari, Zeynab

    2016-12-15

    Formaldehyde removal from an air stream absorbed into a water stream in a packed bed continuously and then removed by employing a combination of UV and ferrate(VI) as a highly-powerful oxidant in a continuous stirred tank. In addition, the removal of formaldehyde from water was investigated in both batch and continuous modes. The results of the study performed on formaldehyde-contaminated water treatment can be used for both air and water treatment process design. The primary objective of this study is to compare the performance of using UV and ferrate(VI) individually with that of using UV/ferrate(VI) simultaneously to remove formaldehyde from both air and water. Moreover, the effects of several factors such as pH, ferrate(VI) concentration and temperature on formaldehyde removal from water using ferrate(VI) method were evaluated. The results of the current study in batch condition showed that the best initial pH and ferrate(VI) concentration to obtain the highest formaldehyde removal are 2 and 1 mg/l, respectively. The results of this part of research also reveal that temperatures rise from 25 °C to 50 °C increases formaldehyde removal from 69% to 97%; however, further increase in temperature has an adverse effect on removal efficiency. The combination of UV and ferrate(VI) enhances formaldehyde removal efficiency to very close to 100% within 35 min. In continuous air stream treatment, maximum formaldehyde removal of 94% was obtained by using a packed bed scrubber with gas over liquid flow rates ratio of 1.28 m(3)/m(3). Although the results of this study shows that ferrate(VI) method for removal of formaldehyde can be considered as a promising alternative for both water and air treatment, further economic studies are required for this process to be commercialized. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Layered Double Hydroxides as Effective Adsorbents for U(VI and Toxic Heavy Metals Removal from Aqueous Media

    Directory of Open Access Journals (Sweden)

    G. N. Pshinko

    2013-01-01

    Full Text Available Capacities of different synthesized Zn,Al-hydrotalcite-like adsorbents, including the initial carbonate [Zn4Al2(OH12]·CO3·8H2O and its forms intercalated with chelating agents (ethylenediaminetetraacetic acid (EDTA, diethylenetriaminepentaacetic acid (DTPA, and hexamethylenediaminetetraacetic acid (HMDTA and heat-treated form Zn4Al2O7, to adsorb uranium(VI and ions of toxic heavy metals have been compared. Metal sorption capacities of hydrotalcite-like adsorbents have been shown to correlate with the stability of their complexes with the mentioned chelating agents in a solution. The synthesized layered double hydroxides (LDHs containing chelating agents in the interlayer space are rather efficient for sorption purification of aqueous media free from U(VI irrespective of its forms of natural abundance (including water-soluble bi- and tricarbonate forms and from heavy metal ions. [Zn4Al2(OH12]·EDTA·nH2O is recommended for practical application as one of the most efficient and inexpensive synthetic adsorbents designed for recovery of both cationic and particularly important anionic forms of U(VI and other heavy metals from aqueous media. Carbonate forms of LDHs turned out to be most efficient for recovery of Cu(II from aqueous media with pH0≥7 owing to precipitation of Cu(II basic carbonates and Cu(II hydroxides. Chromate ions are efficiently adsorbed from water only by calcinated forms of LDHs.

  13. Now, It's Your Turn: How You Can Take Medicine Safely

    Science.gov (United States)

    ... turn Javascript on. Feature: Taking Medicines Safely Now, It's Your Turn: How You Can Take Medicine Safely ... medicine. The pharmacist has filled the prescription. Now it's up to you to take the medicine safely. ...

  14. Turning Gravitationally Lensed Supernovae into Cosmological Probes

    Science.gov (United States)

    Roberts-Pierel, Justin

    2017-08-01

    Recent HST observations have been critically important for twolandmark discoveries of gravitationally lensed supernovae: the firstmultiply-imaged SN, Refsdal, and the first Type Ia SN resolved intomultiple images, SN iPTF16geu. Fitting the multiple light curves ofsuch objects can deliver measurements of the lensing time delays,which in turn provide precise tests of lens models or uniqueconstraints on the Hubble constant and other cosmological parameters.For both of these SNe, initial constraints on the time delays havebeen limited by the need to account for subtle microlensingeffects. We will perform a complete reanalysis of both SN Refsdal andSN iPTF16geu, in order to refine estimates of their lensingmagnifications and time delays. Our work will improve upon previousefforts by revising the data processing and photometry, and includingthe significant yet previously ignored effects ofmicrolensing. Additionally, we will develop a publicly availablesoftware package in the course of this work, optimized specificallyfor multiply-imaged SNe. This software will be an important tool inthe next decade, supporting precise time delay measurements of tens tohundreds of lensed SNe to be found with LSST and WFIRST.

  15. Cosmopolitan Pluralism: Beyond the Cultural Turn

    Directory of Open Access Journals (Sweden)

    Stephanie Lawson

    2011-11-01

    Full Text Available The ‘cultural turn’ has had a profound influence across the humanities and social sciences in the last few decades. In calling into question the universalist basis on which conventional methodological and normative assumptions have been based, the cultural turn has focused on the extent to which specificity and particularity underpin what we can know, how we can know it, and how this affects our being-in-the world. This has opened the way to a range of insights, from issues of pluralism and difference, both within political communities and between them, to the instability if not impossibility of foundations for knowledge. Too few studies embracing this ‘cultural turn’, however, pay more than cursory attention to the culture concept itself. This article suggests that conceptions of culture derived mainly from the discipline of anthropology dominate in political studies, including international relations, while humanist conceptions have been largely ignored or rejected. It argues further that we would do well to reconsider what humanist ideas can contribute to how ‘culture’ is both conceptualized and deployed in political thought and action, especially in countering the overparticularization of social and political phenomena that marks contemporary culturalist approaches.

  16. IMPLEMENTATION PRINCIPLES – TURNING INTENTIONS INTO OUTCOMES

    Directory of Open Access Journals (Sweden)

    N. Faull

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Companies sometimes fail to take effective action even when they know what they should do. Recent research shows that this surprising situation is more common than one would expect. How can the track record of companies in achieving the outcomes targeted by manufacturing strategy be improved? This article proposes a set of eight principles to improve the chances of taking effective action to turn intentions into outcomes. Rooted in the literature, the principles have also surfaced in case based research and commented on in the context of international consulting activities.

    AFRIKAANSE OPSOMMING: Dit gebeur partykeer dat maatskappye nie doelgerig optree nie, ook al weet hulle wat hulle moet doen. Onlangse navorsing dui aan dat so 'n verrassende situasie meer algemeen is as wat mens sou verwag. Hoe kan die baanrekord van maatskapye verbeter word om doelwitte wat in bedryfsstrategie gestel word werklik te beryk? Hierdie artikel stel ‚n reeks van agt beginsels voor om die kans dat effektiewe aksie geneem word om wense in uitslae te omskep, te verbeter. Die beginsels, gewortel in die literatuur, het ook in gevallestudie-gebaseerde navorsing ter sprake gekom en word hier bespreek in die konteks van internasionale raadgewende werk.

  17. Identification of active anti-inflammatory principles of beta- beta ...

    African Journals Online (AJOL)

    Purpose: To identify the anti-inflammatory components of beta-beta (Lunasia amara Blanco.) wood. Methods: The wood material was extracted with 96 % ethanol and fractionated with dichloromethane using a liquid-liquid continuous extraction (LLCE). The fractions were subjected to silica gel column chromatography.

  18. Beta section beta : biogeographical patterns of variation, and taxonomy

    NARCIS (Netherlands)

    Letschert, J.P.W.

    1993-01-01

    In Chapter 1 an account is given of the historical subdivision of the genus Beta and its sections, and the relations of the sections are discussed. Emphasis is given to the taxonomic treatment of wild section Beta by various authors. The Linnaean

  19. Conversion of beta-methylbutyric acid to beta-hydroxy-beta-methylbutyric acid by Galactomyces reessii.

    OpenAIRE

    Lee, I. Y.; Nissen, S L; Rosazza, J P

    1997-01-01

    beta-Hydroxy-beta-methylbutyric acid (HMB) has been shown to increase strength and lean mass gains in humans undergoing resistance-exercise training. HMB is currently marketed as a calcium salt of HMB, and thus, environmentally sound and inexpensive methods of manufacture are being sought. This study investigates the microbial conversion of beta-methylbutyric acid (MBA) to HMB by cultures of Galactomyces reessii. Optimal concentrations of MBA were in the range of 5 to 20 g/liter for HMB produ...

  20. History of Education in Canada: Historiographic "Turns" and Widening Horizons

    Science.gov (United States)

    Bruno-Jofré, Rosa

    2014-01-01

    This paper explores major historiographic "turns" in history of education with a focus, although not exclusively, on English-speaking Canada. It addresses the transformative intellectual impact of the turn toward social history on the history of education, the impact of cultural history and the linguistic turn, the reception of Michel…

  1. Turn Openings in Academic Talk: Where Goals and Roles Intersect

    Science.gov (United States)

    Evison, Jane

    2013-01-01

    This study uses Corpus Linguistic (CL) techniques to explore multiple turn openings in conjunction with comparative measures of turn-initial priming (the proportion of occurrences of a form that are turn-initial). Using a benchmark corpus of casual conversation as a point of comparison, six frequent items which have a particularly strong affinity…

  2. 33 CFR 164.42 - Rate of turn indicator.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Rate of turn indicator. 164.42...) PORTS AND WATERWAYS SAFETY NAVIGATION SAFETY REGULATIONS § 164.42 Rate of turn indicator. Each vessel of... turn indicator. ...

  3. Molecular evolution of type VI intermediate filament proteins

    Directory of Open Access Journals (Sweden)

    Vincent Michel

    2007-09-01

    Full Text Available Abstract Background Tanabin, transitin and nestin are type VI intermediate filament (IF proteins that are developmentally regulated in frogs, birds and mammals, respectively. Tanabin is expressed in the growth cones of embryonic vertebrate neurons, whereas transitin and nestin are found in myogenic and neurogenic cells. Another type VI IF protein, synemin, is expressed in undifferentiated and mature muscle cells of birds and mammals. In addition to an IF-typical α-helical core domain, type VI IF proteins are characterized by a long C-terminal tail often containing distinct repeated motifs. The molecular evolution of type VI IF proteins remains poorly studied. Results To examine the evolutionary history of type VI IF proteins, sequence comparisons, BLAST searches, synteny studies and phylogenic analyses were performed. This study provides new evidence that tanabin, transitin and nestin are indeed orthologous type VI IF proteins. It demonstrates that tanabin, transitin and nestin genes share intron positions and sequence identities, have a similar chromosomal context and display closely related positions in phylogenic analyses. Despite this homology, fast evolution rates of their C-terminal extremity have caused the appearance of repeated motifs with distinct biological activities. In particular, our in silico and in vitro analyses of their tail domain have shown that (avian transitin, but not (mammalian nestin, contains a repeat domain displaying nucleotide hydrolysis activity. Conclusion These analyses of the evolutionary history of the IF proteins fit with a model in which type VI IFs form a branch distinct from NF proteins and are composed of two major proteins: synemin and nestin orthologs. Rapid evolution of the C-terminal extremity of nestin orthologs could be responsible for their divergent functions.

  4. Expert recommendations for the laboratory diagnosis of MPS VI.

    Science.gov (United States)

    Wood, T; Bodamer, O A; Burin, M G; D'Almeida, V; Fietz, M; Giugliani, R; Hawley, S M; Hendriksz, C J; Hwu, W L; Ketteridge, D; Lukacs, Z; Mendelsohn, N J; Miller, N; Pasquali, M; Schenone, A; Schoonderwoerd, K; Winchester, B; Harmatz, P

    2012-05-01

    Mucopolysaccharidosis VI (MPS VI) is a lysosomal storage disease caused by a deficiency of N-acetylgalactosamine 4-sulfatase (arylsulfatase B, ASB). This enzyme is required for the degradation of dermatan sulfate. In its absence, dermatan sulfate accumulates in cells and is excreted in large quantities in urine. Specific therapeutic intervention is available; however, accurate and timely diagnosis is crucial for maximal benefit. To better understand the current practices for diagnosis and to establish diagnostic guidelines, an international MPS VI laboratory diagnostics scientific summit was held in February of 2011 in Miami, Florida. The various steps in the diagnosis of MPS VI were discussed including urinary glycosaminoglycan (uGAG) analysis, enzyme activity analysis, and molecular analysis. The following conclusions were reached. Dilute urine samples pose a significant problem for uGAG analysis and MPS VI patients can be missed by quantitative uGAG testing alone as dermatan sulfate may not always be excreted in large quantities. Enzyme activity analysis is universally acknowledged as a key component of diagnosis; however, several caveats must be considered and the appropriate use of reference enzymes is essential. Molecular analysis supports enzyme activity test results and is essential for carrier testing, subsequent genetic counseling, and prenatal testing. Overall the expert panel recommends caution in the use of uGAG screening alone to rule out or confirm the diagnosis of MPS VI and acknowledges enzyme activity analysis as a critical component of diagnosis. Measurement of another sulfatase enzyme to exclude multiple sulfatase deficiency was recommended prior to the initiation of therapy. When feasible, the use of molecular testing as part of the diagnosis is encouraged. A diagnostic algorithm for MPS VI is provided. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Tomographic reconstruction of transverse phase space from turn-by-turn profile data

    CERN Document Server

    Hancock, S; Lindroos, M

    1999-01-01

    Tomographic methods have the potential for useful application in beam diagnostics. The tomographic reconstruction of transverse phase space density from turn-by-turn profile data has been studied with particular attention to the effects of dispersion and chromaticity. It is shown that the modified Algebraic Reconstruction Technique (ART) that deals successfully with the problem of non-linear motion in the longitudinal plane cannot, in general, be extended to cover the transverse case. Instead, an approach is proposed in which the effect of dispersion is deconvoluted from the measured profiles before the phase space picture is reconstructed using either the modified ART algorithm or the inverse Radon Transform. This requires an accurate knowledge of the momentum distribution of the beam and the modified ART reconstruction of longitudinal phase space density yields just such information. The method has been tested extensively with simulated data.

  6. Model-independent analysis of the Fermilab Tevatron turn-by-turn beam position monitor measurements

    Energy Technology Data Exchange (ETDEWEB)

    Petrenko, A.V.; /Novosibirsk, IYF; Valishev, A.A.; Lebedev, V.A.; /Fermilab

    2011-09-01

    Coherent transverse beam oscillations in the Tevatron were analyzed with the model-independent analysis (MIA) technique. This allowed one to obtain the model-independent values of coupled betatron amplitudes, phase advances, and dispersion function around the ring from a single dipole kick measurement. In order to solve the MIA mode mixing problem which limits the accuracy of determination of the optical functions, we have developed a new technique of rotational MIA mode untangling. The basic idea is to treat each beam position monitor (BPM) as two BPMs separated in a ring by exactly one turn. This leads to a simple criterion of MIA mode separation: the betatron phase advance between any BPM and its counterpart shifted by one turn should be equal to the betatron tune and therefore should not depend on the BPM position in the ring. Furthermore, we describe a MIA-based technique to locate vibrating magnets in a storage ring.

  7. Type VI Secretion System in Pseudomonas aeruginosa

    Science.gov (United States)

    Hachani, Abderrahman; Lossi, Nadine S.; Hamilton, Alexander; Jones, Cerith; Bleves, Sophie; Albesa-Jové, David; Filloux, Alain

    2011-01-01

    Pseudomonas aeruginosa is a Gram-negative bacterium causing chronic infections in cystic fibrosis patients. Such infections are associated with an active type VI secretion system (T6SS), which consists of about 15 conserved components, including the AAA+ ATPase, ClpV. The T6SS secretes two categories of proteins, VgrG and Hcp. Hcp is structurally similar to a phage tail tube component, whereas VgrG proteins show similarity to the puncturing device at the tip of the phage tube. In P. aeruginosa, three T6SSs are known. The expression of H1-T6SS genes is controlled by the RetS sensor. Here, 10 vgrG genes were identified in the PAO1 genome, among which three are co-regulated with H1-T6SS, namely vgrG1a/b/c. Whereas VgrG1a and VgrG1c were secreted in a ClpV1-dependent manner, secretion of VgrG1b was ClpV1-independent. We show that VgrG1a and VgrG1c form multimers, which confirmed the VgrG model predicting trimers similar to the tail spike. We demonstrate that Hcp1 secretion requires either VgrG1a or VgrG1c, which may act independently to puncture the bacterial envelope and give Hcp1 access to the surface. VgrG1b is not required for Hcp1 secretion. Thus, VgrG1b does not require H1-T6SS for secretion nor does H1-T6SS require VgrG1b for its function. Finally, we show that VgrG proteins are required for secretion of a genuine H1-T6SS substrate, Tse3. Our results demonstrate that VgrG proteins are not only secreted components but are essential for secretion of other T6SS substrates. Overall, we emphasize variability in behavior of three P. aeruginosa VgrGs, suggesting that, although very similar, distinct VgrGs achieve specific functions. PMID:21325275

  8. Elucidating the mechanism of Cr(VI) formation upon the interaction with metal oxides during coal oxy-fuel combustion

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Juan [Department of Chemical Engineering, Monash University, Clayton, GPO Box 36, Victoria 3800 (Australia); State Key Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan 430074 (China); Jiao, Facun [Department of Applied Chemistry, Chubu University, 1200 Matsumoto-Cho, Kasugai, Aichi 487-8501 (Japan); Zhang, Lian, E-mail: lian.zhang@monash.edu [Department of Chemical Engineering, Monash University, Clayton, GPO Box 36, Victoria 3800 (Australia); Yao, Hong [State Key Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan 430074 (China); Ninomiya, Yoshihiko [Department of Applied Chemistry, Chubu University, 1200 Matsumoto-Cho, Kasugai, Aichi 487-8501 (Japan)

    2013-10-15

    Highlights: • The presence of Ca{sup 2+}/K{sup +} oxide in coal favored the enrichment of toxic Cr(VI) in coal combustion derived fly ash. • Fe{sub 2}O{sub 3} and MgO in coal are critical on the inhibition of Cr(VI) formation during coal combustion. • Cr(VI) formation extent is correlated positively with the standard reduction potential of metal oxide in coal. -- Abstract: The thermodynamics underpinning the interaction of Cr-bearing species with basic metal oxides, i.e. K{sub 2}O, Fe{sub 2}O{sub 3}, MgO and CaO, during the air and oxy-fuel combustion of coal have been examined. The synchrotron-based X-ray adsorption near-edge spectroscopy (XANES) was used for Cr speciation. For the oxides tested, Cr(VI) formation is dominated by the reduction potential of the metals. The oxides of Ca{sup 2+} with high reduction potential favored the oxidation of Cr(III), same for K{sup +}. The other two basic metals, Fe{sub 2}O{sub 3} and MgO with lower reduction potentials reacted with Cr(III) to form the corresponding chromites at the temperatures above 600 °C. Coal combustion experiments in drop-tube furnace have confirmed the rapid capture of Cr vapors, either trivalent or hexavalent, by CaO into solid ash. The existence of HCl in flue gas favored the vaporization of Cr as CrO{sub 2}Cl{sub 2}, which was in turn captured by CaO into chromate. Both Fe{sub 2}O{sub 3} and MgO exhibited less capability on scavenging the Cr(VI) vapor. Particularly, MgO alone exhibited a low capability for capturing the vaporized Cr(III) vapors. However, its co-existence with CaO in the furnace inhibited the Cr(VI) formation. This is beneficial for minimizing the toxicity of Cr in the coal combustion-derived fly ash.

  9. Turned On / Turned Off: Speculating on the Microchip-based Contraceptive Implant

    DEFF Research Database (Denmark)

    Homewood, Sarah; Heyer, Clint

    2017-01-01

    For over 50 years, hormone-based contraceptives have allowed women to control their fertility, thus reconfiguring society and how women relate to their body. On the horizon are long-life microchip-based implanted contraceptives that can be turned on and off, which may further the societal...... discussions around security, relationships and hormones. Drawing from the outcomes of the workshop, we produce a speculative design in the form of a film and physical mock-ups....

  10. Turn-Based War Chess Model and Its Search Algorithm per Turn

    Directory of Open Access Journals (Sweden)

    Hai Nan

    2016-01-01

    Full Text Available War chess gaming has so far received insufficient attention but is a significant component of turn-based strategy games (TBS and is studied in this paper. First, a common game model is proposed through various existing war chess types. Based on the model, we propose a theory frame involving combinational optimization on the one hand and game tree search on the other hand. We also discuss a key problem, namely, that the number of the branching factors of each turn in the game tree is huge. Then, we propose two algorithms for searching in one turn to solve the problem: (1 enumeration by order; (2 enumeration by recursion. The main difference between these two is the permutation method used: the former uses the dictionary sequence method, while the latter uses the recursive permutation method. Finally, we prove that both of these algorithms are optimal, and we analyze the difference between their efficiencies. An important factor is the total time taken for the unit to expand until it achieves its reachable position. The factor, which is the total number of expansions that each unit makes in its reachable position, is set. The conclusion proposed is in terms of this factor: Enumeration by recursion is better than enumeration by order in all situations.

  11. Beta Function and Anomalous Dimensions

    DEFF Research Database (Denmark)

    Pica, Claudio; Sannino, Francesco

    2011-01-01

    We demonstrate that it is possible to determine the coefficients of an all-order beta function linear in the anomalous dimensions using as data the two-loop coefficients together with the first one of the anomalous dimensions which are universal. The beta function allows to determine the anomalous...

  12. RAVEN Beta Release

    Energy Technology Data Exchange (ETDEWEB)

    Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert Arthur [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wang, Congjian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Maljovec, Daniel Patrick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Talbot, Paul William [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-02-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  13. Sasse Modeling of First Cycle Neptunium (VI) Recovery Flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    Laurinat, J. E. [Savannah River Site (SRS), Aiken, SC (United States)

    2006-04-01

    A flowsheet has been proposed to separate neptunium from solutions in H-Canyon Tanks 16.4, 12.5, and 11.7 in the First Cycle solvent extraction banks, in which cerium(IV) (Ce(IV)) serves as an agent to oxidize neptunium to neptunium(VI) (Np(VI)). A SASSE (Spreadsheet Algorithm for Stagewise Solvent Extraction) spreadsheet model indicates that the proposed flowsheet is a feasible method for separating neptunium and uranium from sulfates, thorium, and other metal impurities. The proposed flowsheet calls for stripping the sulfates, thorium, and other metal impurities into the 1AW stream and extracting and then stripping the neptunium and uranium into the 1BP stream. SASSE predicts that separation of thorium from the other actinides can be accomplished with actinide losses of 0.01% or less. It is assumed that other metal impurities such as iron, aluminum, and fission products will follow the thorium into 1AW. Due to an organic/aqueous distribution coefficient that is close to one, SASSE predicts that plutonium(VI) (Pu(VI)) is split between the A Bank and B Bank aqueous output streams, with 27% going to 1AW and 73% going to 1BP. An extrapolated distribution coefficient based on unvalidated Ce(IV) distribution measurements at a single nitrate concentration and a comparison with thorium(IV) (Th(IV)) distributions indicates that Ce(IV) could reflux in 1B Bank. If the Ce(IV) distribution coefficient is lower than would be predicted by this single point extrapolation, but still higher than the distribution coefficient for Th(IV), then Ce(IV) would follow Np(VI) and uranium(VI) (U(VI)) into 1BP. The SASSE model was validated using data from a 1964 oxidizing flowsheet for the recovery of Np(VI) in Second Cycle. For the proposed flowsheet to be effective in recovering neptunium, the addition of approximately 0.025 M ceric ammonium nitrate (Ce(NH4)2(NO3)6) to both the 1AF and 1AS streams is required to stabilize the neptunium in the +6

  14. Beta Beams Implementation at CERN

    CERN Document Server

    Hansen, Christian

    2011-01-01

    Beta Beam,the concept of generating a pure and intense (anti) neutrino beam by letting accelerated radioactive ions beta decay in a storage ring, called Decay Ring (DR), is the base of one of the proposed next generation neutrino oscillation facilities, necessary for a complete study of the neutrino oscillation parameter space. Sensitivities of the unknown neutrino oscillation parameters depend on the Decay Ring's ion intensity and of it's duty factor (the filled ratio of the ring). Therefore efficient ion production, stripping, bunching, acceleration and storing are crucial sub-projects under study and development within the Beta Beam collaboration. Specifically the feasibility of these tasks as parts of a Beta Beam implementation at CERN will be discussed in this report. The positive impact of the large {\\theta}13 indications from T2K on the Beta Beam performance will also be discussed.

  15. Integrated Cr(VI) removal using constructed wetlands and composting.

    Science.gov (United States)

    Sultana, Mar-Yam; Chowdhury, Abu Khayer Md Muktadirul Bari; Michailides, Michail K; Akratos, Christos S; Tekerlekopoulou, Athanasia G; Vayenas, Dimitrios V

    2015-01-08

    The present work was conducted to study integrated chromium removal from aqueous solutions in horizontal subsurface (HSF) constructed wetlands. Two pilot-scale HSF constructed wetlands (CWs) units were built and operated. One unit was planted with common reeds (Phragmites australis) and one was kept unplanted. Influent concentrations of Cr(VI) ranged from 0.5 to 10mg/L. The effect of temperature and hydraulic residence time (8-0.5 days) on Cr(VI) removal were studied. Temperature was proved to affect Cr(VI) removal in both units. In the planted unit maximum Cr(VI) removal efficiencies of 100% were recorded at HRT's of 1 day with Cr(VI) concentrations of 5, 2.5 and 1mg/L, while a significantly lower removal rate was recorded in the unplanted unit. Harvested reed biomass from the CWs was co-composted with olive mill wastes. The final product had excellent physicochemical characteristics (C/N: 14.1-14.7, germination index (GI): 145-157%, Cr: 8-10mg/kg dry mass), fulfills EU requirements and can be used as a fertilizer in organic farming. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Can Beta Blockers Cause Weight Gain?

    Science.gov (United States)

    Beta blockers: Do they cause weight gain? Can beta blockers cause weight gain? Answers from Sheldon G. Sheps, ... can occur as a side effect of some beta blockers, especially the older ones, such as atenolol (Tenormin) ...

  17. New generation ion-imprinted nanocarrier for removal of Cr(VI) from wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Uygun, Murat, E-mail: muygun@adu.edu.tr [Adnan Menderes University, Kocarl Latin-Small-Letter-Dotless-I Vocational and Training School (Turkey); Feyzioglu, Esra; Oezcal Latin-Small-Letter-Dotless-I skan, Emir; Caka, Mueserref; Ergen, Aygen; Akgoel, Sinan [Ege University, Department of Biochemistry, Faculty of Science (Turkey); Denizli, Adil [Hacettepe University, Department of Chemistry, Faculty of Science (Turkey)

    2013-08-15

    The purpose of this study was to prepare a novel ion-imprinted nanoparticle to remove Cr(VI) ions from waste water. For this, Cr(VI) ions were complexed with 2-methacryloylamido histidine (MAH) and then Cr(VI)-imprinted poly(HEMAH) nanoparticles were synthesized by surfactant-free emulsion polymerization technique. The templates, Cr(VI) ions, were removed from the nanoparticles using 0.1 M of HNO{sub 3} solution. The specific surface area of the Cr(VI)-imprinted poly(HEMAH) nanoparticles was found to be 1,397.85 m{sup 2}/g, and the particle size was calculated as 155.3 nm. These Cr(VI)-imprinted nanoparticles were used for the adsorption/desorption of Cr(VI) ions from its aqueous solutions. The effects of initial Cr(VI) concentration and medium pH on the Cr(VI) adsorption capacity were also studied. The maximum adsorbed amount of Cr(VI) on the imprinted nanoparticles was found to be 3,830.58 mg/g nanoparticle in pH 4.0. In order to investigate the selectivity of the imprinted nanoparticle, adsorption studies were repeated using Cr(III) ions. The selectivity results demonstrated that Cr(VI)-imprinted poly(HEMAH) nanoparticles showed high affinity for the Cr(VI) ions than Cr(III). The Cr(VI)-imprinted nanoparticles were used several times without decreasing their Cr(VI) adsorption capacities.

  18. Nitrate Enhanced Microbial Cr(VI) Reduction-Final Report

    Energy Technology Data Exchange (ETDEWEB)

    John F. Stolz

    2011-06-15

    A major challenge for the bioremediation of radionuclides (i.e., uranium, technetium) and metals (i.e., Cr(VI), Hg) is the co-occurrence of nitrate as it can inhibit metal transformation. Denitrification (nitrate reduction to dinitrogen gas) is considered the most important ecological process. For many metal and metalloid reducing bacteria, however, ammonia is the end product through respiratory nitrate reduction (RNRA). The focus of this work was to determine how RNRA impacts Cr(VI) transformation. The goal was to elucidate the specific mechanism(s) that limits Cr(VI) reduction in the presence of nitrate and to use this information to develop strategies that enhance Cr(VI) reduction (and thus detoxification). Our central hypothesis is that nitrate impacts the biotransformation of metals and metalloids in three ways 1) as a competitive alternative electron acceptor (inhibiting transformation), 2) as a co-metabolite (i.e., concomitant reduction, stimulating transformation), and 3) as an inducer of specific proteins and pathways involved in oxidation/reduction reactions (stimulating transformation). We have identified three model organisms, Geobacter metallireducens (mechanism 1), Sulfurospirillum barnesii, (mechasism 2), and Desulfovibrio desulfuricans (mechanisms 3). Our specific aims were to 1) investigate the role of Cr(VI) concentration on the kinetics of both growth and reduction of nitrate, nitrite, and Cr(VI) in these three organisms; 2) develop a profile of bacterial enzymes involved in nitrate transformation (e.g., oxidoreductases) using a proteomic approach; 3) investigate the function of periplasmic nitrite reductase (Nrf) as a chromate reductase; and 4) develop a strategy to maximize microbial chromium reduction in the presence of nitrate. We found that growth on nitrate by G. metallireducens was inhibited by Cr(VI). Over 240 proteins were identified by LC/MS-MS. Redox active proteins, outer membrane heavy metal efflux proteins, and chemotaxis sensory

  19. Learning/Work: Turning Work and Lifelong Learning inside out

    Science.gov (United States)

    Walters, Shirley; Cooper, Linda

    2011-01-01

    CONFINTEA VI took place against the background of an uneven and contradictory social and economic impact of globalisation. This impact registered globally and locally, in both the political North and South, drawing new lines of inequality between "core" and "periphery", between insiders and outsiders of contemporary society. Financial turmoil in…

  20. Isolation of a star-shaped uranium(V/VI) cluster from the anaerobic photochemical reduction of uranyl(VI)

    Energy Technology Data Exchange (ETDEWEB)

    Chatelain, Lucile; White, Sarah; Scopelliti, Rosario; Mazzanti, Marinella [Ecole Polytechnique Federale de Lausanne (EPFL) (Switzerland). Inst. de Sciences et Ingenierie Chimiques

    2016-11-07

    Actinide oxo clusters are an important class of compounds due to their impact on actinide migration in the environment. The photolytic reduction of uranyl(VI) has potential application in catalysis and spent nuclear fuel reprocessing, but the intermediate species involved in this reduction have not yet been elucidated. Here we show that the photolysis of partially hydrated uranyl(VI) in anaerobic conditions leads to the reduction of uranyl(VI), and to the incorporation of the resulting U{sup V} species into the stable mixed-valent star-shaped U{sup VI}/U{sup V} oxo cluster [U(UO{sub 2}){sub 5}(μ{sub 3}-O){sub 5}(PhCOO){sub 5}(Py){sub 7}]. This cluster is only the second example of a U{sup VI}/U{sup V} cluster and the first one associating uranyl groups to a non-uranyl(V) center. The U{sup V} center in 1 is stable, while the reaction of uranyl(V) iodide with potassium benzoate leads to immediate disproportionation and formation of the U{sub 12}{sup IV}U{sub 4}{sup V}O{sub 24} cluster {[K(Py)_2]_2[K(Py)]_2[U_1_6O_2_4(PhCOO)_2_4(Py)_2]}.

  1. Revisiting GNRA and UNCG folds: U-turns versus Z-turns in RNA hairpin loops.

    Science.gov (United States)

    D'Ascenzo, Luigi; Leonarski, Filip; Vicens, Quentin; Auffinger, Pascal

    2017-03-01

    When thinking about RNA three-dimensional structures, coming across GNRA and UNCG tetraloops is perceived as a boon since their folds have been extensively described. Nevertheless, analyzing loop conformations within RNA and RNP structures led us to uncover several instances of GNRA and UNCG loops that do not fold as expected. We noticed that when a GNRA does not assume its "natural" fold, it adopts the one we typically associate with a UNCG sequence. The same folding interconversion may occur for loops with UNCG sequences, for instance within tRNA anticodon loops. Hence, we show that some structured tetranucleotide sequences starting with G or U can adopt either of these folds. The underlying structural basis that defines these two fold types is the mutually exclusive stacking of a backbone oxygen on either the first (in GNRA) or the last nucleobase (in UNCG), generating an oxygen-π contact. We thereby propose to refrain from using sequences to distinguish between loop conformations. Instead, we suggest using descriptors such as U-turn (for "GNRA-type" folds) and a newly described Z-turn (for "UNCG-type" folds). Because tetraloops adopt for the largest part only two (inter)convertible turns, we are better able to interpret from a structural perspective loop interchangeability occurring in ribosomes and viral RNA. In this respect, we propose a general view on the inclination for a given sequence to adopt (or not) a specific fold. We also suggest how long-noncoding RNAs may adopt discrete but transient structures, which are therefore hard to predict. © 2017 D'Ascenzo et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  2. Sådan skaber vi mønsterbrydere

    DEFF Research Database (Denmark)

    Jensen, Bente

    2017-01-01

    Treårigt forskningsprojekt viser, at pædagoger og medhjælpere kan undersøtte alle børns trivsel og udvikling og dermed styrke udsatte børns ressourcer. det vil kjælpe med at bryde den sociale arv og forhindre, at vi reproducerer ulighed.......Treårigt forskningsprojekt viser, at pædagoger og medhjælpere kan undersøtte alle børns trivsel og udvikling og dermed styrke udsatte børns ressourcer. det vil kjælpe med at bryde den sociale arv og forhindre, at vi reproducerer ulighed....

  3. Sådan bekæmper vi skattely

    DEFF Research Database (Denmark)

    Christensen, Rasmus Corlin; Mondrup Pedersen, Mikkel

    2016-01-01

    I kampens hede er det belejligt at skyde skylden på Nordea og Mossack Fonseca, men skal vi skattely til livs, kræver det en mere omfattende reformation af det internationale skattesystem. Her er de tre største udfordringer......I kampens hede er det belejligt at skyde skylden på Nordea og Mossack Fonseca, men skal vi skattely til livs, kræver det en mere omfattende reformation af det internationale skattesystem. Her er de tre største udfordringer...

  4. Nonspecificity of bacterial reduction of Cr(VI)

    Energy Technology Data Exchange (ETDEWEB)

    Gvozdyak, P.I.; Mogilevich, N.F.; Ryl' skiy, A.F.; Grishchenko, N.I.

    1985-03-01

    Eight different genera of gram-positive and negative bacteria were tested for their ability to carry out reduction of Cr(VI) to Cr(III). The results demonstrated that in addition to Pseudomonas the other genera capable of similar enzymatic activity were Achromobacter, Bacillus and Micrococcus. These observations indicate that reduction of Cr(VI) is not a unique feature of Pseudomonas alone, and that the availability of other bacteria with similar metabolic potential expands the possibility of their utilization in water treatment and possibly in metallurgical enrichment biotechnology. 15 references.

  5. Experiments on double beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Busto, J. [Neuchatel Univ. (Switzerland). Inst. de Physique

    1996-11-01

    The Double Beta Decay, and especially ({beta}{beta}){sub 0{nu}} mode, is an excellent test of Standard Model as well as of neutrino physics. From experimental point of view, a very large number of different techniques are or have been used increasing the sensitivity of this experiments quite a lot (the factor of 10{sup 4} in the last 20 years). In future, in spite of several difficulties, the sensitivity would be increased further, keeping the interest of this very important process. (author) 4 figs., 5 tabs., 21 refs.

  6. Variants of beta-glucosidase

    Energy Technology Data Exchange (ETDEWEB)

    Fidantsef, Ana; Lamsa, Michael; Gorre-Clancy, Brian

    2015-07-14

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  7. Variants of beta-glucosidases

    Energy Technology Data Exchange (ETDEWEB)

    Fidantsef, Ana; Lamsa, Michael; Gorre-Clancy, Brian

    2014-10-07

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  8. Variants of beta-glucosidase

    Science.gov (United States)

    Fidantsef, Ana [Davis, CA; Lamsa, Michael [Davis, CA; Gorre-Clancy, Brian [Elk Grove, CA

    2009-12-29

    The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

  9. Modeling the mechanism of CLN025 beta-hairpin formation

    Science.gov (United States)

    McKiernan, Keri A.; Husic, Brooke E.; Pande, Vijay S.

    2017-09-01

    Beta-hairpins are substructures found in proteins that can lend insight into more complex systems. Furthermore, the folding of beta-hairpins is a valuable test case for benchmarking experimental and theoretical methods. Here, we simulate the folding of CLN025, a miniprotein with a beta-hairpin structure, at its experimental melting temperature using a range of state-of-the-art protein force fields. We construct Markov state models in order to examine the thermodynamics, kinetics, mechanism, and rate-determining step of folding. Mechanistically, we find the folding process is rate-limited by the formation of the turn region hydrogen bonds, which occurs following the downhill hydrophobic collapse of the extended denatured protein. These results are presented in the context of established and contradictory theories of the beta-hairpin folding process. Furthermore, our analysis suggests that the AMBER-FB15 force field, at this temperature, best describes the characteristics of the full experimental CLN025 conformational ensemble, while the AMBER ff99SB-ILDN and CHARMM22* force fields display a tendency to overstabilize the native state.

  10. Direct measurement of neutrino mass utilizing beta decay of tritium

    Energy Technology Data Exchange (ETDEWEB)

    Kawakami, Hirokane (Tokyo Univ., Tanashi (Japan). Inst. for Nuclear Study)

    1992-10-01

    Among elementary particles, neutrino is the queer, wondrous elementary particle that has asymmetric property, and in spite of strenuous efforts, its mass has not been determined. The mass value expected for electron neutrino is as extremely small as several tens eV, but its value may control the future of the space whether this vast space continues to expand as it is or turns to contract. Accordingly, it has become a very important subject for space physics as well as elementary particle physics. The mass of neutrino has been considered to be nearly zero, but in 1980, the USSR group gave the finite value of 14-46 eV for the first time. Since then, the experiments for verifying this result were begun in more than ten places in the world. The method of measuring the mass of neutrino is that by precisely measuring with a beta ray analyzer the vicinity of the maximum value in the continuous energy spectra of the electron beam emitted simultaneously with neutrinos in the beta decay of tritium, and determining the mass from its form. [pi][radical]2 type air core beta ray analyzer, beta ray source, electron detector, the comparison of the contents of the published experiments, and the results of measurement are reported. (K.I.).

  11. Dosimetry of {beta} extensive sources; Dosimetria de fuentes {beta} extensas

    Energy Technology Data Exchange (ETDEWEB)

    Rojas C, E.L.; Lallena R, A.M. [Departamento de Fisica Moderna, Universidad de Granada, E-18071 Granada (Spain)

    2002-07-01

    In this work, we have been studied, making use of the Penelope Monte Carlo simulation code, the dosimetry of {beta} extensive sources in situations of spherical geometry including interfaces. These configurations are of interest in the treatment of the called cranealfaringyomes of some synovia leisure of knee and other problems of interest in medical physics. Therefore, its application can be extended toward problems of another areas with similar geometric situation and beta sources. (Author)

  12. Use of oral contraceptives and serum beta-carotene

    DEFF Research Database (Denmark)

    Berg, Gabriele; Kohlmeier, L; Brenner, H

    1997-01-01

    OBJECTIVE: Antioxidants, in particular carotenoids, may influence the risk for cardiovascular disease. This study investigates the influence of oral contraceptives (OC) on the serum concentration of beta-carotene, which may in turn affect the risk of cardiovascular diseases due to its antioxidative...... impact. DESIGN: Cross-sectional epidemiologic study. Examinations included a detailed questionnaire on medical history and lifestyle factors, a 7 day food record, and blood samples. SETTING: National health and nutrition survey among healthy people living in private homes in West Germany in 1987...... with higher estrogen content. CONCLUSIONS: OC use seems to be strongly related to serum beta-carotene levels, particularly among women above the age of 35. Further studies are needed to clarify the underlying mechanisms of this association and its implications for health risks of OC use....

  13. The turning point in the number of traffic fatalities

    DEFF Research Database (Denmark)

    Brüde, Ulf; Elvik, Rune

    2015-01-01

    The number of traffic fatalities reached a peak in many highly motorised countries around 1970. Some previous studies have suggested that the turning point in the number of traffic fatalities was inevitable and did not reflect a change in the underlying trends influencing the number of traffic...... fatalities. Other studies suggest that trends in traffic growth and fatality rate changed from before to after the turning point. This paper proposes two hypotheses about the turning point in the number of traffic fatalities. One hypothesis is that the long-term trends in traffic growth and fatality rate...... were the same before and after the turning point. The other hypothesis is that the long-term trends in traffic growth and fatality rate were different before and after the turning point was reached, in particular that the annual percentage decline in fatality rate became greater after the turning point...

  14. Analysis of a turning point problem in flight trajectory optimization

    Science.gov (United States)

    Gracey, C.

    1989-01-01

    The optimal control policy for the aeroglide portion of the minimum fuel, orbital plane change problem for maneuvering entry vehicles is reduced to the solution of a turning point problem for the bank angle control. For this problem a turning point occurs at the minimum altitude of the flight, when the flight path angle equals zero. The turning point separates the bank angle control into two outer solutions that are valid away from the turning point. In a neighborhood of the turning point, where the bank angle changes rapidly, an inner solution is developed and matched with the two outer solutions. An asymptotic analysis of the turning point problem is given, and an analytic example is provided to illustrate the construction of the bank angle control.

  15. Subtype-selective modulation of human beta 1- and beta 2-adrenoceptor function by beta-adrenoceptor agonists and antagonists

    NARCIS (Netherlands)

    Brodde, O. E.; Daul, A.; Michel, M. C.

    1990-01-01

    In healthy volunteers a 14-day treatment with the selective beta 1-adrenoceptor agonist xamoterol (2 x 200 mg/day) desensitized beta 1-adrenoceptor-mediated physiological effects, but did not affect beta 2-adrenoceptor-mediated effects; in contrast, a 9-day treatment with the selective beta

  16. Selective regulation of beta 1- and beta 2-adrenoceptors in the human heart by chronic beta-adrenoceptor antagonist treatment

    NARCIS (Netherlands)

    Michel, M. C.; Pingsmann, A.; Beckeringh, J. J.; Zerkowski, H. R.; Doetsch, N.; Brodde, O. E.

    1988-01-01

    1. In 44 patients undergoing coronary artery bypass grafting, the effect of chronic administration of the beta-adrenoceptor antagonists sotalol, propranolol, pindolol, metoprolol and atenolol on beta-adrenoceptor density in right atria (containing 70% beta 1- and 30% beta 2-adrenoceptors) and in

  17. Isolation and characterization of Cr(VI)-reducing actinomycetes from estuarine sediments.

    Science.gov (United States)

    Terahara, Takeshi; Xu, Xudan; Kobayashi, Takeshi; Imada, Chiaki

    2015-04-01

    Bioremediation technologies have strong potential use in the less costly and more environmentally friendly removal of highly toxic hexavalent-chromium (Cr(VI)) compared with physicochemical technologies. Several Cr(VI)-reducing bacteria have been isolated; however, there are few studies on Cr(VI)-resistant and Cr(VI)-reducing actinomycetes. In this study, Cr(VI)-reducing actinomycetes were screened from estuarine, marine, and terrestrial samples on the basis of Cr(VI)-resistant and Cr(VI)-reducing ability. Of the 80 Streptomyces-like strains isolated, 20 strains were found to be resistant to 50 mg/l of Cr(VI). In addition, two strains isolated from the estuarine sediment of Tokyo Bay were found to be resistant to a concentration of 150 mg/l of Cr(VI). Furthermore, one Cr(VI)-reducing strain was found to remove 60 mg/l of Cr(VI) within 1 week and was identified as Streptomyces thermocarboxydus based on 16S rRNA gene analysis. The comparative evaluation with the type strain S. thermocarboxydus NBRC 16323 showed that our isolated strain had higher ability to grow at 27 °C and reduce Cr(VI) at a NaCl concentration of 6.0 % at 27 °C compared with the type strain NBRC 16323. These results indicate that our isolated strain have a potential ability to remove Cr(VI) from contaminated, highly saline sources without heating.

  18. Contribution of extracellular polymeric substances from Shewanella sp. HRCR-1 biofilms to U(VI) immobilization.

    Science.gov (United States)

    Cao, Bin; Ahmed, Bulbul; Kennedy, David W; Wang, Zheming; Shi, Liang; Marshall, Matthew J; Fredrickson, Jim K; Isern, Nancy G; Majors, Paul D; Beyenal, Haluk

    2011-07-01

    The goal of this study was to quantify the contribution of extracellular polymeric substances (EPS) to U(VI) immobilization by Shewanella sp. HRCR-1. Through comparison of U(VI) immobilization using cells with bound EPS (bEPS) and cells with minimal EPS, we show that (i) bEPS from Shewanella sp. HRCR-1 biofilms contribute significantly to U(VI) immobilization, especially at low initial U(VI) concentrations, through both sorption and reduction; (ii) bEPS can be considered a functional extension of the cells for U(VI) immobilization and they likely play more important roles at lower initial U(VI) concentrations; and (iii) the U(VI) reduction efficiency is dependent upon the initial U(VI) concentration and decreases at lower concentrations. To quantify the relative contributions of sorption and reduction to U(VI) immobilization by EPS fractions, we isolated loosely associated EPS (laEPS) and bEPS from Shewanella sp. HRCR-1 biofilms grown in a hollow fiber membrane biofilm reactor and tested their reactivity with U(VI). We found that, when reduced, the isolated cell-free EPS fractions could reduce U(VI). Polysaccharides in the EPS likely contributed to U(VI) sorption and dominated the reactivity of laEPS, while redox active components (e.g., outer membrane c-type cytochromes), especially in bEPS, possibly facilitated U(VI) reduction.

  19. Anticipation in turn-taking: mechanisms and information sources

    Directory of Open Access Journals (Sweden)

    Carina eRiest

    2015-02-01

    Full Text Available During conversations participants alternate smoothly between speaker and hearer roles with only brief pauses and overlaps. There are two competing types of accounts about how conversationalists accomplish this: (a the signalling approach and (b the anticipatory (‘projection’ approach. We wanted to investigate, first, the relative merits of these two accounts, and second, the relative contribution of semantic and syntactic information to the timing of next turn initiation. We performed three button-press experiments using turn fragments taken from natural conversations to address the following questions: (a Is turn-taking predominantly based on anticipation or on reaction, and (b what is the relative contribution of semantic and syntactic information to accurate turn-taking. In our first experiment we gradually manipulated the information available for anticipation of the turn end (providing information about the turn end in advance to completely removing linguistic information. The results of our first experiment show that the distribution of the participants’ estimation of turn-endings for natural turns is very similar to the distribution for pure anticipation. We conclude that listeners are indeed able to anticipate a turn-end and that this strategy is predominantly used in turn-taking. In Experiment 2 we collected purely reacted responses. We used the distributions from Experiments 1 and 2 together to estimate a new dependent variable called Reaction Anticipation Proportion (RAP. We used this variable in our third experiment where we manipulated the presence vs absence of semantic and syntactic information by low-pass filtering open-class and closed class words in the turn. The results suggest that for turn-end anticipation, both semantic and syntactic information are needed, but that the semantic information is a more important anticipation cue than syntactic information.

  20. Anticipation in turn-taking: mechanisms and information sources.

    Science.gov (United States)

    Riest, Carina; Jorschick, Annett B; de Ruiter, Jan P

    2015-01-01

    During conversations participants alternate smoothly between speaker and hearer roles with only brief pauses and overlaps. There are two competing types of accounts about how conversationalists accomplish this: (a) the signaling approach and (b) the anticipatory ('projection') approach. We wanted to investigate, first, the relative merits of these two accounts, and second, the relative contribution of semantic and syntactic information to the timing of next turn initiation. We performed three button-press experiments using turn fragments taken from natural conversations to address the following questions: (a) Is turn-taking predominantly based on anticipation or on reaction, and (b) what is the relative contribution of semantic and syntactic information to accurate turn-taking. In our first experiment we gradually manipulated the information available for anticipation of the turn end (providing information about the turn end in advance to completely removing linguistic information). The results of our first experiment show that the distribution of the participants' estimation of turn-endings for natural turns is very similar to the distribution for pure anticipation. We conclude that listeners are indeed able to anticipate a turn-end and that this strategy is predominantly used in turn-taking. In Experiment 2 we collected purely reacted responses. We used the distributions from Experiments 1 and 2 together to estimate a new dependent variable called Reaction Anticipation Proportion. We used this variable in our third experiment where we manipulated the presence vs. absence of semantic and syntactic information by low-pass filtering open-class and closed class words in the turn. The results suggest that for turn-end anticipation, both semantic and syntactic information are needed, but that the semantic information is a more important anticipation cue than syntactic information.

  1. Adsorption Properties of Bentonite with In Situ Immobilized Polyaniline Towards Anionic Forms of Cr(VI, Mo(VI, W(VI, V(V

    Directory of Open Access Journals (Sweden)

    Kateryna RYABCHENKO

    2016-05-01

    Full Text Available A new composite material bentonite-PANI was synthesized by in situ immobilization of polyaniline (PANI on the surface of natural mineral bentonite. It was established as a result of the modification of bentonite a surface area and an interlayer distance of mineral decrease and particles of bentonite transformed of irregular shape with different porosity on irregularly shaped particles of smaller size. It has been found that the total Cr(VI ions extraction took place under the acid conditions (pH=1 – 2 and W(VI ions have been well adsorbed in the pH range from 1 to 8 by the composite bentonite-PANI unlike the initial mineral. Whereas adsorption of oxo anions of V(V and Mo(VI made up some 50%. It is proved that the in situ immobilization of bentonite by polyaniline leads to increasing the value of adsorption capacity towards the investigated ions compared with the initial mineral. It was established that the adsorption properties of the synthesized composite with respect to the studied oxo ions were worse than the adsorption properties of composite vermiculite-PANI, similar to the composite Sokyryntsyy clinoptilolite-PANI and better than composites of polyaniline with Podilskyy saponite and Karelian shungite.DOI: http://dx.doi.org/10.5755/j01.ms.22.2.6976

  2. Beta-Testing Agreement | FNLCR

    Science.gov (United States)

    Beta-Testing Agreements are appropriate forlimited term evaluation and applications development of new software, technology, or equipment platforms by the Frederick National Labin collaboration with an external commercial partner. It may

  3. Beta-carotene blood test

    Science.gov (United States)

    ... medlineplus.gov/ency/article/003571.htm Beta-carotene blood test To use the sharing features on this page, ... skin is broken) Alternative Names Carotene test Images Blood test References Chernecky CC, Berger BJ. Carotene - serum. In: ...

  4. Eye movements differ between ictal ipsilateral and contralateral head turning.

    Science.gov (United States)

    Baysal-Kirac, Leyla; Rémi, Jan; Loesch, Anna Mira; Hartl, Elisabeth; Vollmar, Christian; Noachtar, Soheyl

    2015-08-01

    This study evaluated the relation of head and eye movements during ictal ipsilateral and contralateral head turning in patients with focal epilepsies with regard to lateralization of the epileptogenic zone. We reviewed our database and identified patients with ictal head turning ipsilateral and contralateral to the seizure onset as defined by ictal EEG. Twenty-seven seizures of 19 consecutive patients with ipsilateral and 40 seizures of 32 patients with contralateral head turning were investigated. Twenty-four patients had temporal lobe epilepsy (TLE), and 27 patients had extratemporal or multifocal epilepsy. Eye movement in the same direction preceded contralateral head turning in 90% (36 of 40 seizures) of the seizures, but this was the case in only 33% (9 of 27 seizures) of the ipsilateral ictal head turning. In contrary, head turning preceded the eye movements in 67% (18 of 27 seizures) of the ipsilateral ictal head turning and in only 10% of the contralateral head turning (p eye movements is different in ictal ipsilateral and contralateral head turning movements which likely reflects different spread patterns of epileptic activity associated with activation of different generators. The analysis of eye movements adds to the lateralization of ictal head movements. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Group IB Organometallic Chemistry XXXIV: Thermal behavior and chemical reactivity of tetranuclear Me2N-substituted diarylpropenylcopper-copper anion (Vi2Cu4X2) and mixed diarylpropenyl/organocopper (Vi2Cu4R2) compounds

    NARCIS (Netherlands)

    Koten, G. van; Hoedt, R.W.M. ten; Noltes, J.G.

    1980-01-01

    Thermal decomposition of configurationally pure 1, 2-diarylpropenylcopper compounds Z-Vi{2}CU{4}Br{2} and Z-Vi{2}Cu{4}R{2} [Vi @? (2-Me{2}NC{6}H{4})C@?C(Me)-(C{6}H{4}Me-4), R @? 2-Me{2}NC{6}H{4} or 4-MeC{6}H{4}C@?C] predominantly results in the formation of ViH. In contrast, only dimers (ViVi) were

  6. As duas naturezas de Lévi-Strauss

    Directory of Open Access Journals (Sweden)

    Philippe Descola

    2011-11-01

    Full Text Available Aborda-se aqui a complexidade do status do par conceitual natureza e cultura no pensamento de Lévi-Strauss. Ao mesmo tempo ferramenta de análise, cena filosófica dos primórdios e antinomia a superar, revisita-se os diferentes usos e significados na obra de Lévi-Strauss do conceito de natureza e sua relação com o de cultura. Mostra-se como é possível reconhecer na obra de Lévi-Strauss dois conceitos de natureza: por um lado, uma natureza que se opõe à cultura num programa científico formulado em termos classicamente dualistas e, por outro, uma teoria do conhecimento decididamente monista que considera o espírito como parte e produto desse mesmo mundo. Argumenta-se que se o dualismo entre cultura e natureza fundou o pensamento estruturalista de Lévi-Strauss, é na própria obra deste que encontramos os argumentos e meios de superá-lo. A vocação do estruturalismo na antropologia de hoje, no entanto, é de ir mais longe neste caminho do que foi o próprio fundador.

  7. Anesthetic Challenges in an Adult with Mucopolysaccharidosis Type VI.

    Science.gov (United States)

    Cade, Jacqueline; Jansen, Nicholas

    2014-06-15

    The mucopolysaccharidoses are a group of lysosomal storage diseases with many skeletal and airway features that pose a challenge to anesthetists. We present the anesthetic management of a woman with mucopolysaccharidosis type VI undergoing cervical spine surgery and review the perioperative issues that may arise with this disease.

  8. Resúmenes Presentaciones de Pósteres VI ECAP

    OpenAIRE

    Vargas Arana, Editor Gabriel

    2016-01-01

    En este artículo se pueden encontrar los resúmenes de las presentaciones de pósteres del VI Encuentro Científico de la Amazonía Peruana, desarrollado el 27 y 28 de octubre de 2016 en la ciudad de Iquitos, Perú.

  9. Mechanism for partial oxidation of Cyclohexene by Chromium (VI ...

    African Journals Online (AJOL)

    The oxidation of cyclohexene by chromium (VI) oxide in aqueous and acetic media has been studied. The reaction products were analysed using classical method, IR and GC/MS analyses. The major products of the oxidation reaction in acetic acid medium are cyclohexanol, cyclohexanone, cyclohex-2-en-1-one, ...

  10. Removal of Cr(VI) from groundwater by Fe(0)

    Science.gov (United States)

    Gao, Yanjiao; Liu, Rui

    2017-11-01

    This research was conducted to investigate the treatment of hexavalent chromium (Cr(VI)) by iron powder (Fe(0)) columns of simulated permeable reactive barriers with and without calcium carbonate (CaCO3). Two columns filled with Fe(0) were used as Cr(VI) removal equipment running at a flow velocity of 10 ml/min at room temperature. After 200 days running of the two columns, the results showed that Fe(0) was an effective material for Cr(VI) reduction with an average removal rate of above 84.6%. The performance of Column 2 with CaCO3 was better than Column 1 without CaCO3 in terms of average Cr(VI) removal rate. The presence of CaCO3 buffered the increasing pH caused by Fe(0) corrosion in Column 2 and enhanced the removal rate of Column 2. Scanning Electron Microscopy (SEM) images of Fe(0) in the three stages of running of the two columns illustrated that the coat layer of Column 1 was a little thicker than that of Column 2. Energy-dispersive spectrometry (EDS) results showed that the surface of Fe(0) of Column 2 contained more chromium elements. Raman spectroscopy found that all iron oxide was generated on the Fe(0) surface of Column 1 and Column 2 and chromium class objects were only detected on Fe(0) surface in Column 2.

  11. Vi har beskæftigelseskrise, ikke uddannelseskrise

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou; Skou Grindsted, Louise

    2014-01-01

    Universiteterne er for dårlige, og kandidaternes kompetencer er forkerte, derfor ender mange i arbejdsløshed, mener Danmarks Akkrediteringsinstitution, Produktivitetskommissionen og DI. Men for få år siden var der mangel på højtuddannet arbejdskraft, så måske har vi et beskæftigelsesproblem snarere...

  12. Revolutsioonilisest ja igavikulisest VI Tallinna arhitektuuritriennaalil / Ave Randviir

    Index Scriptorium Estoniae

    Randviir, Ave, 1981-

    2005-01-01

    Tallinna arhitektuuritriennaali idee sünnist. 1990.a. toimus esimene triennaal nimega Põhja- ja Baltimaade Arhitektuuritriennaal. Niguliste kirikus toimunud VI Tallinna arhitektuuritriennaalist. Korraldajaks Irina Raud. Tunnuslauseks "Feeling Architecture". Triennaali avanud ja lõpetanud Peter Davey ja teiste esinejate ettekannetest. Eestlastest esinesid Juhan Maiste ja Vilen Künnapu

  13. Biosorption of hexavalent chromium (chromium (VI) ion from ...

    African Journals Online (AJOL)

    taye

    2015-04-01

    Apr 1, 2015 ... An experimental effluent analysis was conducted in conjunction with bioremediation process from ... Hexavalent Chromium (Cr (VI) is a by-product released .... Agriculture waste either saw dust or rice husk was procured from. Sabon Gari market, Zaria, Nigeria and brought to the Laboratory for analysis.

  14. Upper Limits on O VI Emission from Voyager Observations

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    The data processing is described in Murthy et al. (1999) and resulted in 426 obser- vations of the ... We detect no O VI emission in any of 426 UVS observations of the diffuse radiation field but do set upper limits on such ... Assuming that the emitting gas has a solar abundance of helium atoms and that the hydrogen and ...

  15. Finite difference simulation of biological chromium (VI) reduction in ...

    African Journals Online (AJOL)

    2013-05-08

    May 8, 2013 ... precipitates of reduced chromium produce toxic sludge that may be difficult to remediate (Gonzalez et al., 2003; Blowes, 2002). Recent studies have shown the possibility of using locally isolated organisms to treat Cr(VI) contaminated groundwater and/or soil. The treatment can be implemented ex situ ...

  16. Individual and Group Extension Methods: Perspectives from Vi ...

    African Journals Online (AJOL)

    A study was conducted to assess the effectiveness of group and individual extension methods in delivering agroforestry technologies at Vi-Agroforestry project, Masaka district. Participatory Rural Appraisals (PRAs) tools including semi-structured questionnaires were administrated to 90 randomly selected farmers who had ...

  17. Upper Limits on O VI Emission from Voyager Observations

    Indian Academy of Sciences (India)

    We have examined 426 Voyager fields distributed across the sky for O VI ( 1032/1038 Å) emission from the Galactic diffuse interstellar medium. No such emission was detected in any of our observed fields. Our most constraining limit was a 90% confidence upper limit of 2600 photons cm-2 sr-1 s-1 on the doublet ...

  18. Evaluation of Cr (VI) remediation potential of Eichornia sp in ...

    African Journals Online (AJOL)

    Purpose: Evaluation of Cr (VI) removal by indigenous chromium resistant bacterial strains alone and in combination with Eichornia sp. Methods: Three chromium resistant bacterial strains S-4 Ochrobactrum grignonense, SF-5 Bacillus sp. and S-6 Ochrobactrum pseudogrignonenses were isolated from industrial effluent.

  19. Social Set Visualizer (SoSeVi) II

    DEFF Research Database (Denmark)

    Flesch, Benjamin; Vatrapu, Ravi

    2016-01-01

    This paper reports the second iteration of the Social Set Visualizer (SoSeVi), a set theoretical visual analytics dashboard of big social data. In order to further demonstrate its usefulness in large-scale visual analytics tasks of individual and collective behavior of actors in social networks...

  20. Osteogenesis Imperfecta Type VI in Individuals from Northern Canada.

    Science.gov (United States)

    Ward, Leanne; Bardai, Ghalib; Moffatt, Pierre; Al-Jallad, Hadil; Trejo, Pamela; Glorieux, Francis H; Rauch, Frank

    2016-06-01

    Osteogenesis imperfecta (OI) type VI is a recessively inherited form of OI that is caused by mutations in SERPINF1, the gene coding for pigment-epithelium derived factor (PEDF). Here, we report on two apparently unrelated children with OI type VI who had the same unusual homozygous variant in intron 6 of SERPINF1 (c.787-10C>G). This variant created a novel splice site that led to the in-frame addition of three amino acids to PEDF (p.Lys262_Ile263insLeuSerGln). Western blotting showed that skin fibroblasts with this mutation produced PEDF but failed to secrete it. Both children were treated with intravenous bisphosphonates, but the treatment of Individual 1 was switched to subcutaneous injections of denosumab (dose 1 mg per kg body weight, repeated every 3 months). An iliac bone sample obtained after 5 denosumab injections (and 3 months after the last injection) showed no change in the increased osteoid parameters that are typical of OI type VI, but the number of osteoclasts in trabecular bone was markedly increased. This suggests that the effect of denosumab on osteoclast suppression is of shorter duration in children with OI type VI than what has previously been reported on adults with osteoporosis.

  1. Selective removal of chromium (VI) from sulphates and other metal ...

    African Journals Online (AJOL)

    2011-10-06

    Oct 6, 2011 ... (Leonberg, Germany) equipped with a Lambda 1010 UV-Vis absorbance detector was ... AG 7 (4 x 50 mm) guard column and Dionex IonPac® AS7 (4 x. 250 mm) analytical ...... and equilibrium characterization of uranium(VI) adsorption onto .... netic nanoparticles in a polyvinylpyridine matrix. Polymer 41.

  2. Chromium(III) -- chromium(VI) interconversions in seawater

    NARCIS (Netherlands)

    Weijden, C.H. van der; Reith, M.

    1982-01-01

    The stable form of dissolved chromium in oxygenated seawater is Cr(VI). But Cr(III)-species are also present at an analytically significant level. It is shown that Cr(III) is oxidized only slowly by dissolved oxygen, and that manganese oxide is a strong catalyst for such oxidation. However, the low

  3. BEHA VI OUR OF TOPI IN A SHADELESS ENVIRONMENT ...

    African Journals Online (AJOL)

    BEHA VI OUR OF TOPI IN A SHADELESS ENVIRONMENT. P. J. JARMAN-. Department of ... them for much of the year medium-length, fairly green, leafy swards of grass. The vegetation types containing ... one population for signs of behavioural adaptiveness in the species' environmental relation- ships. -Present address: ...

  4. Leveraging Information Technology. Track VI: Hardware/Software Strategies.

    Science.gov (United States)

    CAUSE, Boulder, CO.

    Seven papers from the 1987 CAUSE conference's Track VI, Hardware/Software Strategies, are presented. They include: "Integrated Systems--The Next Steps" (Morris A. Hicks); "Administrative Microcomputing--Roads Traveled, Lessons Learned" (David L. Smallen); "Murphy's First Law and Its Application to Administrative…

  5. Paisaje del viñedo: patrimonio y recurso

    Directory of Open Access Journals (Sweden)

    Luis Vicente Elías

    2008-01-01

    Full Text Available La propuesta de que el paisaje del viñedo sea el complemento a la visita a la bodega, siendo esta el eje del turismo del vino, es el objetivo de este trabajo. Repasando los conceptos variables de patrimonio, llegamos al paisaje del viñedo como recurso, formando parte del patrimonio natural. Pero este no se puede desvincular de los otros aspectos patrimoniales, por lo que la cultura tradicional es el soporte de la tipología de paisaje que queremos proponer y que va contrastar con los nuevos paisajes del viñedo que surgen de las recientes técnicas en los cultivos y de la actual vitivicultura, emparejada con una moderna “cultura del vino”. El análisis de las diversas normativas, que salvaguardan el paisaje y la comprobación del escaso valor legal del paisaje del viñedo, es otro puntal de este trabajo que trata de unir paisaje con cultura tradicional como recursos del Turismo del Vino, integrados en las Rutas del Vino.

  6. Selective removal of chromium (VI) from sulphates and other metal ...

    African Journals Online (AJOL)

    Leaching of the chromate template from the polymer particles was achieved with successive stirring of the ion-imprinted polymer (IIP) particles in 4 M HNO3 solutions to obtain leached materials, which were then used for selective rebinding of Cr (VI) ions from aqueous solutions. Similarly, the non-imprinted polymer/control ...

  7. ViPiA: A Project for European Entrepreneurship

    Science.gov (United States)

    Folinas, Dimitris; Manthou, Vicky; Vlachopoulou, Maro

    2006-01-01

    The Virtual Pre-Incubator Accelerator (ViPiA) is a two-year project funded by the European Commission. The main goal of the programme is to create a training package for would-be entrepreneurs to assist them in developing their new venture concepts to a level at which they become attractive to potential investors. This paper describes and…

  8. AM(VI) partitioning studies. FY14 final report

    Energy Technology Data Exchange (ETDEWEB)

    Mincher, Bruce J. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-10-01

    The use of higher oxidation states of americium in partitioning from the lanthanides is under continued investigation by the sigma team. This is based on the hypothesis that Am(VI) can be produced and remain stable in irradiated first cycle raffinate solution long enough to perform solvent extraction for separations. The stability of Am(VI) to autoreduction was measured using millimolar americium concentrations in a 1-cm cell with a Cary 6000 UV/Vis spectrophotometer for data acquisition. At millimolar americium concentrations, Am(VI) is stable enough against its own autoreduction for separations purposes. A second major accomplishment during FY14 was the hot test. Americium oxidation and extraction was performed using a centrifugal contactor-based test bed consisting of an extraction stage and two stripping stages. Sixty-three percent americium extraction was obtained in one extraction stage, in agreement with batch contacts. Promising electrochemical oxidation results have also been obtained, using terpyridine ligand derivatized electrodes for binding of Am(III). Approximately 50 % of the Am(III) was oxidized to Am(V) over the course of 1 hour. It is believed that this is the first demonstration of the electrolytic oxidation of americium in a non-complexing solution. Finally, an initial investigation of Am(VI) extraction using diethylhexylbutyramide (DEHBA) was performed.

  9. Chemistry of the Colloidal Group II-VI Nanocrystal Synthesis

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Haitao [Univ. of California, Berkeley, CA (United States)

    2007-05-17

    In the last two decades, the field of nanoscience andnanotechnology has witnessed tremendous advancement in the synthesis andapplication of group II-VI colloidal nanocrystals. The synthesis based onhigh temperature decomposition of organometallic precursors has becomeone of the most successful methods of making group II-VI colloidalnanocrystals. This methodis first demonstrated by Bawendi and coworkersin 1993 to prepare cadmium chalcogenide colloidal quantum dots and laterextended by others to prepare other group II-VI quantum dots as well asanisotropic shaped colloidal nanocrystals, such as nanorod and tetrapod.This dissertation focuses on the chemistry of this type of nanocrystalsynthesis. The synthesis of group II-VI nanocrystals was studied bycharacterizing the molecular structures of the precursors and productsand following their time evolution in the synthesis. Based on theseresults, a mechanism was proposed to account for the 2 reaction betweenthe precursors that presumably produces monomer for the growth ofnanocrystals. Theoretical study based on density functional theorycalculations revealed the detailed free energy landscape of the precursordecomposition and monomerformation pathway. Based on the proposedreaction mechanism, a new synthetic method was designed that uses wateras a novel reagent to control the diameter and the aspect ratio of CdSeand CdS nanorods.

  10. 1990 Clean Air Act Amendment Summary: Title VI

    Science.gov (United States)

    This page provides an overview of the 1990 amendments to Title VI of the Clean Air Act, which were enacted to curb acid rain, urban air pollution and toxic air emissions. The edits to this title deal with stratospheric ozone and global climate protection.

  11. Adsorption kinetics for the removal of chromium (VI) from aqueous ...

    African Journals Online (AJOL)

    A comparison of kinetic models applied to the adsorption of Cr(VI) ions on the adsorbents was evaluated for the pseudo first-order, the pseudo second-order, Elovich and intraparticle diffusion kinetic models, respectively. Results show that the pseudo second-order kinetic model was found to correlate the experimental data ...

  12. mechanism for partial oxidation of cyclohexene by chromium (vi)

    African Journals Online (AJOL)

    DJFLEX

    The oxidation of cyclohexene by chromium (VI) oxide in aqueous and acetic media has been studied. The reaction products were analysed using classical method, IR and GC/MS analyses. The major products of the oxidation reaction in acetic acid medium are cyclohexanol, cyclohexanone, cyclohex-2-en-1-one, ...

  13. Sorption of environmentally relevant radionuclides (U(VI), Np(V)) and lanthanides (Nd(III)) on feldspar and mica

    Energy Technology Data Exchange (ETDEWEB)

    Richter, Constanze

    2015-11-05

    obtained sorption curves exhibit a similar characteristic for orthoclase and muscovite. As expected Nd(III) shows the highest amount of sorption followed by U(VI) and finally Np(V). With spectroscopic investigations of the aquatic U(VI) solution in presence of Ca{sup 2+}, the Ca{sub 2}UO{sub 2}(CO{sub 3}){sub 3} complex could be identified. Furthermore, with spectroscopic methods the U(VI) surface species onto orthoclase could be characterized, of which a novel uranium-carbonate surface species was observed. Based on the results of batch experiments and spectroscopic methods new SCM parameters for the sorption of U(VI), Np(V), and Nd(III) onto orthoclase and for Np(V) and Nd(III) onto muscovite could be derived. SCM parameters for U(VI) sorption onto muscovite confirmed earlier investigations. The obtained SCM parameters increase the amount of data available for sorption processes onto feldspar and mica. With this the relevance of feldspars for the sorption of actinides and lanthanides could be shown. Thus, this work contributes to a better understanding of interactions of actinides and lanthanides, in particular U(VI), Np(V), and Nd(III), with mineral phases ubiquitous in the environment. This in turn adds confidence to long-term safety assessments essential for the protection of humans and the environment from the hazards of radioactive waste.

  14. Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same

    Science.gov (United States)

    Morant, Marc

    2017-02-07

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  15. Chromium(VI)-resistant yeast isolated from a sewage treatment plant receiving tannery wastes.

    Science.gov (United States)

    Baldi, F; Vaughan, A M; Olson, G J

    1990-01-01

    A Cr(VI)-resistant yeast, designated strain DBVPG 6502, was isolated from a sewage treatment plant receiving wastes from tannery industries in Italy. The strain was tentatively identified as a species of Candida based on morphological and physiological analyses. This strain was highly resistant to Cr(VI) when compared with eight other yeast species, growing at Cr(VI) concentrations of up to 500 micrograms/ml (10 mM). This resistance was constitutive. The Cr(VI)-resistant yeast did not reduce Cr(VI) to Cr(III) species under aerobic conditions. The yeast showed very little accumulation of Cr(VI). Consequently, the mechanism of resistance of the yeast to Cr(VI) appears to involve reduced accumulation of Cr, as has been shown in Cr(VI)-resistant bacteria. Images PMID:2339879

  16. Cr(VI) generation during sample preparation of solid samples – A ...

    African Journals Online (AJOL)

    2009-05-15

    ) extraction should be to quantitatively extract Cr(VI), without inducing changes in speciation, i.e.. Cr(III)/Cr(VI) inter-conversions (Pettine and Capri, 2005). The reviews by Ashley et al. (2003), Broadhurst and Maizda.

  17. Injection Matching Studies using Turn by Turn Beam Profile Measurements in the CERN PS

    CERN Document Server

    Benedikt, Michael; Dutriat, C; Jansson, A; Giovannozzi, Massimo; Martini, M; Raich, U

    2001-01-01

    The very small emittance beam needed for the LHC requires that the emittance blow-up in its injector machines must be kept to a minimum. Mismatch upon the beam transfer from one machine to the next is a potential source of such blow-up. The CERN PS ring is equipped with 3 Secondary Emission Grids (SEM-Grids) which are used for emittance measurement at injection. One of these has been converted to a multi-turn mode, in which several tens of consecutive beam passages can be observed. This allows the study of mismatch between the PS-Booster and the PS. This paper describes the instrument and experimental results obtained during the last year.

  18. Neutrophil beta-2 microglobulin: an inflammatory mediator

    DEFF Research Database (Denmark)

    Bjerrum, O W; Nissen, Mogens Holst; Borregaard, N

    1990-01-01

    vesicles, and plasma membrane. Beta 2m was released in the native form from neutrophils in response to stimulation with chemotactic stimuli and phorbol ester. The results of experiments designed to study the modification of native beta 2m by neutrophils indicated that neutrophils do not participate...... in the proteolysis of beta 2m. However, we demonstrated that native beta 2m following degranulation may be transformed to Des-Lys58-beta 2m by lymphocytes. We suggest that neutrophil beta 2m following exocytosis may be transformed to Des-Lys58-beta 2m, acting as an extracellular messenger between granulocytes...

  19. Interaction of aerobic soil bacteria with plutonium(VI)

    Energy Technology Data Exchange (ETDEWEB)

    Panak, P.J. [Lawrence Berkeley National Lab., Berkeley, CA (United States). Chemical Sciences Div.; Nitsche, H. [Lawrence Berkeley National Lab., Berkeley, CA (United States). Chemical Sciences Div.; California Univ., Berkeley, CA (United States). Dept. of Chemistry

    2001-07-01

    We studied the interaction of Pu(VI) with Pseudomonas stutzeri ATCC 17588 and Bacillus sphaericus ATCC 14577, representatives of the main aerobic groups of soil bacteria present in the upper soil layers. The biosorption studies have shown that these soil bacteria accumulate high amounts of Pu(VI). The relative sorption efficiency toward Pu(VI) related to the amount of biomass used decreased with increasing biomass concentration due to increased agglomeration of the bacteria resulting in a decrease of the number of available complexing groups. Spores of Bacillus sphaericus showed a higher biosorption than the vegetative cells at low biomass concentration which decreased significantly with increasing biomass concentration. At higher biomass concentrations (> 0.7 g/L), the vegetative cells of both strains and the spores of B. sphaericus showed comparable sorption efficiencies. Investigations on the pH dependency of the biosorption and extraction studies with 0.01 M EDTA solution have shown that the biosorption of plutonium is a reversible process and the plutonium is bound by surface complexation. Optical absorption spectroscopy showed that one third of the initially present Pu(VI) was reduced to Pu(V) after 24 hours. Kinetic studies and solvent extraction to separate different oxidation states of Pu after contact with the biomass provided further information on the yield and the kinetics of the bacteria-mediated reduction. Long-term studies showed that also 16% of Pu(IV) was formed after one month. The slow kinetics of this process indicate that under our experimental conditions the Pu(IV) was not a produced by microbial reduction but seemed to be rather the result of the disproportionation of the formed Pu(V) or autoreduction of Pu(VI). (orig.)

  20. Influence of U(VI) on the metabolism of plant cells studied by microcalorimetry and TRLFS

    Energy Technology Data Exchange (ETDEWEB)

    Sachs, Susanne; Geipel, Gerhard [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Biogeochemistry; Fahmy, Karim; Oertel, Jana [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Biophysics; Bok, Frank [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Surface Processes

    2017-06-01

    Uranium(VI) shows a concentration-dependent influence on the metabolic activity of plant cells. With increasing U(VI) concentration, the predominant U(VI) species in medium R{sub red} changes from UO{sub 2}HPO{sub 4}(s) to (UO{sub 2}){sub 3}(OH){sub 5}{sup +}, which may affect the bioavailability of U(VI).

  1. CONNECTION OF TURN AHEAD AND TURN BACK WITH MOTORIC ABILITIES OF THE FOURTH GRADE OF HIGH SCHOOL

    Directory of Open Access Journals (Sweden)

    Jovica Petković

    2008-08-01

    Full Text Available The research is done for the purpose of determination and defining of the level of connection between some motoric abilities with success in realization of programmed contents from the area of gymnastics (turn ahead and turn back. The research is done on the sample of fifty students from the fourth grade of High School, on ten motoric tests and on two specific motoric assignments – turn ahead and turn back. The results of this research clearly point that there exist the multitude of statistically important coefficients of correlation between treated motoric abilities and applied motoric assignments.

  2. Beta decay heat following U-235, U-238 and Pu-239 neutron fission

    Science.gov (United States)

    Li, Shengjie

    1997-09-01

    This is an experimental study of beta-particle decay heat from 235U, 239Pu and 238U aggregate fission products over delay times 0.4-40,000 seconds. The experimental results below 2s for 235U and 239Pu, and below 20s for 238U, are the first such results reported. The experiments were conducted at the UMASS Lowell 5.5-MV Van de Graaff accelerator and 1-MW swimming-pool research reactor. Thermalized neutrons from the 7Li(p,n)7Be reaction induced fission in 238U and 239Pu, and fast neutrons produced in the reactor initiated fission in 238U. A helium-jet/tape-transport system rapidly transferred fission fragments from a fission chamber to a low background counting area. Delay times after fission were selected by varying the tape speed or the position of the spray point relative to the beta spectrometer that employed a thin-scintillator-disk gating technique to separate beta-particles from accompanying gamma-rays. Beta and gamma sources were both used in energy calibration. Based on low-energy(<1 MeV) internal-conversion electron studies, a set of trial responses for the spectrometer was established and spanned electron energies 0-10 MeV. Measured beta spectra were unfolded for their energy distributions by the program FERD, and then compared to other measurements and summation calculations based on ENDF/B-VI fission-product data performed on the LANL Cray computer. Measurements of the beta activity as a function of decay time furnished a relative normalization. Results for the beta decay heat are presented and compared with other experimental data and the summation calculations.

  3. Tables of double beta decay data

    Energy Technology Data Exchange (ETDEWEB)

    Tretyak, V.I. [AN Ukrainskoj SSR, Kiev (Ukraine)]|[Strasbourg-1 Univ., 67 (France). Centre de Recherches Nucleaires; Zdesenko, Y.G. [AN Ukrainskoj SSR, Kiev (Ukraine)

    1995-12-31

    A compilation of experimental data on double beta decay is presented. The tables contain the most stringent known experimental limits or positive results of 2{beta} transitions of 69 natural nuclides to ground and excited states of daughter nuclei for different channels (2{beta}{sup -}; 2{beta}{sup +}; {epsilon}{beta}{sup +}; 2{epsilon}) and modes (0{nu}; 2{nu}; 0{nu}M) of decay. (authors). 189 refs., 9 figs., 3 tabs.

  4. TGF-beta1, -beta2 and -beta3 cooperate to facilitate tubulogenesis in the explanted quail heart.

    Science.gov (United States)

    Holifield, Jennifer S; Arlen, Angela M; Runyan, Raymond B; Tomanek, Robert J

    2004-01-01

    Transforming growth factor-beta (TGF-beta) isoforms have been implicated as both pro- and anti-angiogenic modulators. In this study we addressed the roles of TGF-beta isoforms on coronary tubulogenesis. Embryonic (E6) quail ventricular specimens were explanted onto collagen gels allowing endothelial cells to migrate and form vascular tubes. Growth factors and/or neutralizing growth factor antibodies were added to the cultures. Endothelial cells were identified using a quail endothelial cell marker, QH1. Image analysis was used to quantify aggregate tube length. Addition of any isoform (TGF-beta(1), TGF-beta(2) or TGF-beta(3)) virtually prevented tubulogenesis (>95% inhibition), while stimulation of tubulogenesis occurred by adding neutralizing antibodies to TGF-beta(3), but not to TGF-beta(1) or -beta(2). When all three isoforms were added, tubulogenesis was enhanced, indicating the key role of TGF-beta(3). Documentation of the inhibitory effect of TGF-beta isoforms on tubulogenesis is further supported by our experiments in which the marked enhancement of tube formation by bFGF and VEGF was negated when exogenous TGF-beta(1), -beta(2), or -beta(3) were added to the cultures. (1) TGF-beta(1), -beta(2) and -beta(3) each inhibits angiogenesis; (2) cooperation between the three TGF-beta isoforms and other angiogenic factors is essential for the regulation of normal tubulogenesis and (3) the stimulatory effect of VEGF or bFGF on tubulogenesis is negated by exogenous TGB-betas. Copyright 2004 S. Karger AG, Basel.

  5. The evolution of cooperative turn-taking in animal conflict

    NARCIS (Netherlands)

    Franz, Mathias; van der Post, Daniel; Schuelke, Oliver; Ostner, Julia

    2011-01-01

    Background: A fundamental assumption in animal socio-ecology is that animals compete over limited resources. This view has been challenged by the finding that individuals might cooperatively partition resources by " taking turns". Turn-taking occurs when two individuals coordinate their agonistic

  6. Quasi-Automatic Monitoring System For Turning Operation Using ...

    African Journals Online (AJOL)

    This work discusses the generation of a quasi monitoring system intended for an operator to change cutting tool during turning operation. The monitoring system uses the effects of turning va riables on acoustic emission signal responses and factorial experimental design approach. In cutting operations, acoustic emission ...

  7. Experimentation and Prediction of Temperature Rise in Turning ...

    African Journals Online (AJOL)

    Experimentation and Prediction of Temperature Rise in Turning Process using Response Surface Methodology. ... Reducing the temperature rise during turning operation improves the quality of the product and reduces tool wear. Experiments are conducted as per the Design of Experiments (DoE) of Response Surface ...

  8. Density of Plutonium Turnings Generated from Machining Activities

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, John Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vigil, Duane M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jachimowski, Thomas A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Archuleta, Alonso [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Arellano, Gerald Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Melton, Vince Lee [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-20

    The purpose of this project was to determine the density of plutonium (Pu) turnings generated from the range of machining activities, using both surrogate material and machined Pu turnings. Verify that 500 grams (g) of plutonium will fit in a one quart container using a surrogate equivalent volume and that 100 grams of Pu will fit in a one quart Savy container.

  9. Performance Characteristics of a Cam Turning Attachment | Tuleun ...

    African Journals Online (AJOL)

    A modification of a cylindrical turning unit has been done to give a non-cylindrical turning attachment for production of irregular shapes, like cams on the lathe machine. To assess the performance of the attachment, cutting forces have been measured using a 'Sigma' Cutting Tool Dynamometer. Furthermore, the effect of ...

  10. Fast Turn-off Mine Transient Electromagnetic Transmitter System

    Directory of Open Access Journals (Sweden)

    ZHENG Xiao-Liang

    2014-05-01

    Full Text Available For solving problems such as short turn-off time, high linear degree of falling edge, measurement of turn-off time and influence of primary signals for transient electromagnetic transmitter, and restrictions because of the environmental conditions of underground coal mine, this thesis aims at designing a new transient electromagnetic transmitter system suitable for coal mine. Supported by damping absorption circuit, such system applies small volume, sectional transmitting coil, with features of short turn-off time, high linear degree of current falling edge. It uses the transmitter monitoring circuit, which accurately measures turn-off time and simultaneously records the current value changes after turn-off, thus to eliminate the influence of primary field as well as to restore earlier secondary field signals for reference and finally to improve the ability to detect the shallow structure. It turns out that the new system has a shorter turn-off time, a higher linear degree of current falling and more accurate data record of turn-off current.

  11. Optimizing feed force for turned parts through the Taguchi technique

    Indian Academy of Sciences (India)

    Abstract. The objective of the paper is to obtain an optimal setting of turning process parameters (cutting speed, feed rate and depth of cut) resulting in an optimal value of the feed force when machining EN24 steel with TiC-coated tungsten- carbide inserts. The effects of the selected turning process parameters on feed force.

  12. Human Rights Education and the Post Secular Turn

    Science.gov (United States)

    Bowie, Bob

    2012-01-01

    This article questions whether human rights education (HRE) scholarship is responding adequately to the post secular turn in thinking about the place and nature of religion in society. Here the post secular turn is used to describe the discrediting of secularisation theory, the recognition of religion as an enduring and pervasive global cultural…

  13. Cutting forces during turning with variable depth of cut

    Directory of Open Access Journals (Sweden)

    M. Sadílek

    2016-03-01

    The proposed research for the paper is an experimental work – measuring cutting forces and monitoring of the tool wear on the cutting edge. It compares the turning where standard roughing cycle is used and the turning where the proposed roughing cycle with variable depth of cut is applied.

  14. The effect of temperature on the speciation of U(VI) in sulfate solutions

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Linfeng; Tian, Guoxin

    2008-09-15

    Sulfate, one of the inorganic constituents that could be present in the nuclear waste repository, forms complexes with U(VI) and affects its migration in the environment. Results show that the complexation of U(VI) with sulfate is enhanced by the increase in temperature. The effect of temperature on the complexation and speciation of U(VI) in sulfate solutions is discussed.

  15. Investigations on photoelectrocatalytic reduction of Cr(VI) over titanium dioxide anode and metal cathode

    Energy Technology Data Exchange (ETDEWEB)

    Song, Han; Shang, Jing, E-mail: shangjing@pku.edu.cn; Ye, Junhui; Li, Qian

    2014-01-31

    Photocatalytic and photoelectrocatalytic (PEC) reductions of Cr(VI) based on TiO{sub 2} thin films were investigated under various conditions. Photogenerated electrons transferred from TiO{sub 2} thin film to cathode can contribute to PEC reduction of Cr(VI) only when the Fermi level of cathode lies above the chemical potential of Cr(VI), almost independent on the applied voltage of the direct current. In addition, the TiO{sub 2}-coated anode is the major site that accommodates the PEC reduction of Cr(VI) with hole scavenger citric acid, regardless of the Fermi level of the cathode. Although electron transfer from TiO{sub 2} to Cr(VI) is an exothermic process, the photogenerated holes in TiO{sub 2} can markedly hamper Cr(VI) reduction over the TiO{sub 2} thin film by oxidizing the lower-valence Cr back to Cr(VI), which may be counteracted by the citric acid. This research provides some in-depth insights on developing photocatalysts which enable highly efficient PEC reduction of Cr(VI) in the future. - Highlights: • Cr(VI) reduction on TiO{sub 2} photoanode is dominant with the addition of citric acid. • Cr(VI) is reduced on photocathode with Fermi level above Cr(VI) chemical potential. • Photogenerated holes can hamper Cr(VI) photoreduction over TiO{sub 2}.

  16. 76 FR 62148 - Title VI; Proposed Circular, Environmental Justice; Proposed Circular

    Science.gov (United States)

    2011-10-06

    ... Federal Transit Administration Title VI; Proposed Circular, Environmental Justice; Proposed Circular... information sessions, as published in the September 29, 2011, Federal Register Notices titled ``Title VI... sessions, as published in the September 29, 2011, Federal Register Notices titled ``Title VI; Proposed...

  17. Contribution of Extracellular Polymeric Substances from Shewanella sp. HRCR-1 Biofilms to U(VI) Immobilization

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Bin; Ahmed, B.; Kennedy, David W.; Wang, Zheming; Shi, Liang; Marshall, Matthew J.; Fredrickson, Jim K.; Isern, Nancy G.; Majors, Paul D.; Beyenal, Haluk

    2011-06-05

    The goal of this study was to quantify the contribution of extracellular polymeric substances (EPS) in U(VI) immobilization by Shewanella sp. HRCR-1. Through comparison of U(VI) immobilization using cells with bound EPS (bEPS) and cells without EPS, we showed that i) bEPS from Shewanella sp. HRCR-1 biofilms contributed significantly to U(VI) immobilization, especially at low initial U(VI) concentrations, through both sorption and reduction; ii) bEPS could be considered as a functional extension of the cells for U(VI) immobilization and they likely play more important roles at initial U(VI) concentrations; and iii) U(VI) reduction efficiency was found to be dependent upon initial U(VI) concentration and the efficiency decreased at lower concentrations. To quantify relative contribution of sorption and reduction in U(VI) immobilization by EPS fractions, we isolated loosely associated EPS (laEPS) and bEPS from Shewanella sp. HRCR-1 biofilms grown in a hollow fiber membrane biofilm reactor and tested their reactivity with U(V). We found that, when in reduced form, the isolated cell-free EPS fractions could reduce U(VI). Polysaccharides in the EPS likely contributed to U(VI) sorption and dominated reactivity of laEPS while redox active components (e.g., outer membrane c-type cytochromes), especially in bEPS, might facilitate U(VI) reduction.

  18. Annexin VI is attached to transverse-tubule membranes in isolated skeletal muscle triads.

    Science.gov (United States)

    Barrientos, G; Hidalgo, C

    2002-07-15

    Annexin VI is a 68-kDa protein of the Annexin family, a group of Ca2+-dependent phospholipid-binding proteins widely distributed in mammalian tissues including skeletal muscle. We investigated a) which membrane system contributes Annexin VI to skeletal muscle triads, and b) whether Annexin VI removal affects triad integrity or function. Annexin VI was present in isolated triads and transverse tubules but not in heavy sarcoplasmic reticulum vesicles, indicating that Annexin VI binds to either free or triad-attached transverse tubules. Extraction with EGTA of Annexin VI from triads did not alter their migration as a single band in sucrose density gradients or their ouabain binding-site density, indicating that triad integrity does not require Annexin VI. Caffeine-induced Ca2+ release kinetics and Ca2+ uptake rates were likewise not affected by Annexin VI removal from triads, suggesting that Annexin VI is not involved in these functions. Annexin VI purified from rabbit skeletal muscle displayed Ca2+-dependent binding to liposomes containing phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine. Binding saturated at 1/20 molar ratio phosphatidylinositol 4,5-bisphosphate/phosphatidylcholine and was optimal at free [Ca2+] > or = 20 mM. Extraction of Annexin VI from triads did not affect the generation of phosphatidylinositol 4-phosphate, phosphatidylinositol 4,5-bisphosphate, or phosphatidic acid by endogenous lipid kinases, suggesting that despite its capacity to bind to negatively charged phospholipids, Annexin VI does not affect the kinase activities responsible for their generation.

  19. Efficient removal of Cr(III)-organic complexes from water using UV/Fe(III) system: Negligible Cr(VI) accumulation and mechanism.

    Science.gov (United States)

    Ye, Yuxuan; Jiang, Zhao; Xu, Zhe; Zhang, Xiaolin; Wang, Dandan; Lv, Lu; Pan, Bingcai

    2017-12-01

    Most available processes are incapable of removing Cr(III)-organic complexes from water due to their high solubility, extremely slow decomplexation rate, and possible formation of more toxic Cr(VI) during oxidation. Herein, we proposed a new combined process, i.e., UV/Fe(III) followed by alkaline precipitation (namely UV/Fe(III)+OH), to achieve highly efficient and environmentally benign removal of Cr(III)-organic complexes from water. The combined process could remove Cr(III)-citrate from 10.4 mg Cr/L to 0.36 mg Cr/L and ∼60% total organic carbon as well. More attractively, negligible Cr(VI) (Fe(III) generates ·OH radicals to transform Cr(III) into Cr(VI) and simultaneously released the citrate ligand to form Fe(III)-citrate simultaneously. Then, the photolysis of Fe(III)-citrate under UV irradiation involved the citrate degradation and the production of massive Fe(II) species, which in turn transformed the formed Cr(VI) back to Cr(III). The free metal ions, including Cr(III), Fe(II) and Fe(III) were removed by the subsequent alkaline precipitation. Also, the combined process is applicable to other Cr(III) complexes with EDTA, tartrate, oxalate, acetate. The applicability of the combined process was further demonstrated by treating two real tanning effluents, resulting in the residual Cr(III) below 1.5 mg/L (the discharge standard of China) and negligible formation of Cr(VI) (<0.004 mg/L) as well. In general, the combined process has a great potential for efficient removal of Cr(III) complexes from contaminated waters. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Synergy of photocatalysis and adsorption for simultaneous removal of Cr(VI) and Cr(III) with TiO₂ and titanate nanotubes.

    Science.gov (United States)

    Liu, Wen; Ni, Jinren; Yin, Xiaochen

    2014-04-15

    An one-step efficient simultaneous removal of Cr(VI) and Cr(III) was achieved with mixture of TiO₂ and titanate nanotubes (TNTs). Unlike the conventional two-step Cr removal with a first photocatalytic reduction of Cr(VI) and a subsequent adsorption of Cr(III), the proposed single process significantly reduced reaction time (over 50%). The synergy of photocatalysis and adsorption played an important role in enhancing Cr removal process. The synergetic mechanism was interpreted and indirectly confirmed with H₂O₂ variation during photocatalysis. The instant transfer of the reduced Cr from TiO₂ surface to TNTs interlayer greatly promoted the release of photocatalytic sites of TiO₂, which in turn considerably enhanced photocatalytic activity of TNTs by inhibiting electron-hole pairs recombination. The optimum condition for the whole process was at pH 5. Adsorption of Cr(III) was primarily in the interlayer of TNTs at pH ≤ 5. However, higher pH would lead to precipitation of Cr(OH)₃ onto TNTs as observed by X-ray photoelectron spectroscopy (XPS). Addition of Ca(2+) could promoted photocatalysis owing to its ionic bridging function and form of ≡TiOH(+)-Cr(VI)-Ca(2+)-Cr(VI) linkages, while SO₄(2-) only slightly inhibited photo-reduction of Cr(VI), indicating good synergy of photocatalysis and adsorption even at high ionic strength of electrolyte. Besides, the desorbed TNTs could be easily regenerated by remedying the damaged tubular structure and reused for Cr removal with excellent performance. The outstanding synergetic effects with essential explanation of the mechanism make this study not only fundamentally important but also potentially practical applicable. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. ViSAPy: a Python tool for biophysics-based generation of virtual spiking activity for evaluation of spike-sorting algorithms.

    Science.gov (United States)

    Hagen, Espen; Ness, Torbjørn V; Khosrowshahi, Amir; Sørensen, Christina; Fyhn, Marianne; Hafting, Torkel; Franke, Felix; Einevoll, Gaute T

    2015-04-30

    New, silicon-based multielectrodes comprising hundreds or more electrode contacts offer the possibility to record spike trains from thousands of neurons simultaneously. This potential cannot be realized unless accurate, reliable automated methods for spike sorting are developed, in turn requiring benchmarking data sets with known ground-truth spike times. We here present a general simulation tool for computing benchmarking data for evaluation of spike-sorting algorithms entitled ViSAPy (Virtual Spiking Activity in Python). The tool is based on a well-established biophysical forward-modeling scheme and is implemented as a Python package built on top of the neuronal simulator NEURON and the Python tool LFPy. ViSAPy allows for arbitrary combinations of multicompartmental neuron models and geometries of recording multielectrodes. Three example benchmarking data sets are generated, i.e., tetrode and polytrode data mimicking in vivo cortical recordings and microelectrode array (MEA) recordings of in vitro activity in salamander retinas. The synthesized example benchmarking data mimics salient features of typical experimental recordings, for example, spike waveforms depending on interspike interval. ViSAPy goes beyond existing methods as it includes biologically realistic model noise, synaptic activation by recurrent spiking networks, finite-sized electrode contacts, and allows for inhomogeneous electrical conductivities. ViSAPy is optimized to allow for generation of long time series of benchmarking data, spanning minutes of biological time, by parallel execution on multi-core computers. ViSAPy is an open-ended tool as it can be generalized to produce benchmarking data or arbitrary recording-electrode geometries and with various levels of complexity. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  2. Craniofacial abnormalities in animal models of mucopolysaccharidoses I, VI, and VII.

    Science.gov (United States)

    Sheridan, O; Wortman, J; Harvey, C; Hayden, J; Haskins, M

    1994-01-01

    The genetic mucopolysaccharidoses (MPS) are a family of lysosomal storage diseases resulting from the partial catabolism of several glycosaminoglycans (GAGs). Depending on the particular enzyme deficient in activity, the MPS syndromes are defined into groups MPS I through VII, with several subgroups for a total of 10 disorders. In humans, clinical features include dysostosis multiplex, hepatosplenomegaly, hypertelorism, macroglossia, hypoplastic and irregularly shaped teeth, hyperplastic lips and gingiva, facial dysmorphia, corneal clouding, and mental retardation. MPS I (alpha-L-iduronidase deficiency) and VI (arylsulfatase B deficiency) have been described in cats, MPS VII (beta-glucuronidase deficiency) in dogs. Biochemically, these syndromes appear the same as their human counterparts and have similar clinical characteristics. All are inherited as autosomal recessive traits. The purpose of this study was to analyze the craniofacial aspects of these diseases in the animal models and compare these data with descriptions of the human syndromes. A total of 28 live animals were examined. Thirty-one skulls prepared from postmortem specimens were measured directly and radiographed. Controls were closely related family members of the same sex and similar age without the disease, clinically or biochemically. The data indicated that, as in the human syndromes, each is distinct, and the skull bones most severely affected are those of endochondral origin.

  3. Biological impact of the TSH-beta splice variant in health and disease

    Directory of Open Access Journals (Sweden)

    John R. Klein

    2014-04-01

    Full Text Available Thyroid stimulating hormone (TSH, a glycoprotein hormone composed of alpha and beta chains, is produced by thryrotrope cells of the anterior pituitary. Within the conventional endocrine loop, pituitary-derived TSH binds to receptors in the thyroid, resulting in the release of the thyroid hormones thyroxine (T4 and triiodothyronine (T3. T4 and T3 in turn regulate nearly every aspect of mammalian physiology, including basal metabolism, growth and development, and mood and cognition. Although TSH-beta has been known for years to be produced by cells of the immune system, the significance of that has remained largely unclear. Recently, a splice variant of TSH-beta (TSH-beta-v, which consists of a truncated but biologically functional portion of the native form of TSH-beta, was shown to be produced by bone marrow cells and peripheral blood leukocytes, particularly cells of the myeloid/monocyte lineage. In contrast, full-length native TSH-beta is minimally produced by cells of the immune system. The present article will describe the discovery of the TSH-beta-v and will discuss its potential role in immunity and autoimmunity, inflammation, and bone remodeling.

  4. Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein.

    Directory of Open Access Journals (Sweden)

    Bartolomé Moya

    2009-03-01

    Full Text Available It has long been recognized that the modification of penicillin-binding proteins (PBPs to reduce their affinity for beta-lactams is an important mechanism (target modification by which Gram-positive cocci acquire antibiotic resistance. Among Gram-negative rods (GNR, however, this mechanism has been considered unusual, and restricted to clinically irrelevant laboratory mutants for most species. Using as a model Pseudomonas aeruginosa, high up on the list of pathogens causing life-threatening infections in hospitalized patients worldwide, we show that PBPs may also play a major role in beta-lactam resistance in GNR, but through a totally distinct mechanism. Through a detailed genetic investigation, including whole-genome analysis approaches, we demonstrate that high-level (clinical beta-lactam resistance in vitro, in vivo, and in the clinical setting is driven by the inactivation of the dacB-encoded nonessential PBP4, which behaves as a trap target for beta-lactams. The inactivation of this PBP is shown to determine a highly efficient and complex beta-lactam resistance response, triggering overproduction of the chromosomal beta-lactamase AmpC and the specific activation of the CreBC (BlrAB two-component regulator, which in turn plays a major role in resistance. These findings are a major step forward in our understanding of beta-lactam resistance biology, and, more importantly, they open up new perspectives on potential antibiotic targets for the treatment of infectious diseases.

  5. Deferoxamine pretreatment prevents Cr(VI)-induced nephrotoxicity and oxidant stress: role of Cr(VI) chelation.

    Science.gov (United States)

    Molina-Jijón, Eduardo; Zarco-Márquez, Guillermo; Medina-Campos, Omar Noel; Zataraín-Barrón, Zyanya Lucía; Hernández-Pando, Rogelio; Pinzón, Enrique; Zavaleta, Rosa Marina; Tapia, Edilia; Pedraza-Chaverri, José

    2012-01-27

    Deferoxamine (DFO) is a recognized iron chelator which has been shown to exert nephroprotection in models of toxic nephropathies. In the present work the potential protective effects of DFO against Cr(VI)-induced nephrotoxicity and oxidant stress were evaluated. Rats were injected with a single injection (15mg/kg, s.c.) of potassium dichromate (K(2)Cr(2)O(7)). DFO was given as a single i.p. injection 30min before K(2)Cr(2)O(7) administration at three different doses (100, 200 and 400mg/kg). It was found that DFO pretreatment attenuated, in a dose-dependent way, K(2)Cr(2)O(7)-induced renal dysfunction and structural alterations evaluated by serum creatinine, blood urea nitrogen, creatinine clearance, proteinuria, plasma glutathione peroxidase activity, urinary excretion of N-acetyl-β-d-glucosaminidase and histological analyses. Furthermore, DFO prevented the K(2)Cr(2)O(7)-induced renal oxidant stress and the decrease in the activity of the antioxidant enzymes superoxide dismutase, glutathione reductase, glutathione peroxidase, glutathione-S-transferase and catalase. Finally it was found that DFO, at 400mg/kg, decreases renal Cr(VI) content which prompted us to evaluate the potential Cr(VI) chelating properties of this compound. Indeed was found in an in vitro assay that DFO was an effective Cr(VI) chelator with an IC(50) of 800μg. In additional groups of rats was found that DFO posttreatment was ineffective to attenuate K(2)Cr(2)O(7)-induced nephrotoxicity and renal oxidant stress. Furthermore, DFO was unable to modify urinary excretion of total chromium. The nephroprotective effect of DFO against Cr(VI)-induced nephrotoxicity and oxidant stress may be explained, at least partially, by the ability of DFO to chelate Cr(VI) and to attenuate renal Cr(VI) content. However, it cannot be excluded that the ability of DFO to chelate iron may also be involved in the protection observed in our study. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  6. Experience sharing, emotional reciprocity, and turn-taking

    Directory of Open Access Journals (Sweden)

    Melisa eStevanovic

    2015-04-01

    Full Text Available In this perspective article, we consider the relationship between experience sharing and turn-taking. There is much evidence suggesting that human social interaction is permeated by two temporal organizations: (1 the sequential framework of turn-taking and (2 the concurrent framework of emotional reciprocity. From this perspective, we introduce two alternative hypotheses about how the relationship between experience sharing and turn-taking could be viewed. According to the first hypothesis, the home environment of experience sharing is in the concurrent framework of emotional reciprocity, while the motivation to share experiences is in tension with the sequential framework of turn-taking. According to the second hypothesis, then again, people’s inclination to coordinate their actions in terms of turn-taking is motivated precisely by their propensity to share experiences. We consider theoretical and empirical ideas in favor of both of these hypotheses and discuss their implications for future research.

  7. In-trap decay spectroscopy for {beta}{beta} decays

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, Thomas

    2011-01-18

    The presented work describes the implementation of a new technique to measure electron-capture (EC) branching ratios (BRs) of intermediate nuclei in {beta}{beta} decays. This technique has been developed at TRIUMF in Vancouver, Canada. It facilitates one of TRIUMF's Ion Traps for Atomic and Nuclear science (TITAN), the Electron Beam Ion Trap (EBIT) that is used as a spectroscopy Penning trap. Radioactive ions, produced at the radioactive isotope facility ISAC, are injected and stored in the spectroscopy Penning trap while their decays are observed. A key feature of this technique is the use of a strong magnetic field, required for trapping. It radially confines electrons from {beta} decays along the trap axis while X-rays, following an EC, are emitted isotropically. This provides spatial separation of X-ray and {beta} detection with almost no {beta}-induced background at the X-ray detector, allowing weak EC branches to be measured. Furthermore, the combination of several traps allows one to isobarically clean the sample prior to the in-trap decay spectroscopy measurement. This technique has been developed to measure ECBRs of transition nuclei in {beta}{beta} decays. Detailed knowledge of these electron capture branches is crucial for a better understanding of the underlying nuclear physics in {beta}{beta} decays. These branches are typically of the order of 10{sup -5} and therefore difficult to measure. Conventional measurements suffer from isobaric contamination and a dominating {beta} background at theX-ray detector. Additionally, X-rays are attenuated by the material where the radioactive sample is implanted. To overcome these limitations, the technique of in-trap decay spectroscopy has been developed. In this work, the EBIT was connected to the TITAN beam line and has been commissioned. Using the developed beam diagnostics, ions were injected into the Penning trap and systematic studies on injection and storage optimization were performed. Furthermore, Ge

  8. Beta-blockers for hypertension

    Science.gov (United States)

    Wiysonge, Charles S; Bradley, Hazel A; Volmink, Jimmy; Mayosi, Bongani M; Opie, Lionel H

    2017-01-01

    Background Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. However, the benefit of beta-blockers as first-line therapy for hypertension without compelling indications is controversial. This review is an update of a Cochrane Review initially published in 2007 and updated in 2012. Objectives To assess the effects of beta-blockers on morbidity and mortality endpoints in adults with hypertension. Search methods The Cochrane Hypertension Information Specialist searched the following databases for randomized controlled trials up to June 2016: the Cochrane Hypertension Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (2016, Issue 6), MEDLINE (from 1946), Embase (from 1974), and ClinicalTrials.gov. We checked reference lists of relevant reviews, and reference lists of studies potentially eligible for inclusion in this review, and also searched the the World Health Organization International Clinical Trials Registry Platform on 06 July 2015. Selection criteria Randomised controlled trials (RCTs) of at least one year of duration, which assessed the effects of beta-blockers compared to placebo or other drugs, as first-line therapy for hypertension, on mortality and morbidity in adults. Data collection and analysis We selected studies and extracted data in duplicate, resolving discrepancies by consensus. We expressed study results as risk ratios (RR) with 95% confidence intervals (CI) and conducted fixed-effect or random-effects meta-analyses, as appropriate. We also used GRADE to assess the certainty of the evidence. GRADE classifies the certainty of evidence as high (if we are confident that the true effect lies

  9. Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue

    Directory of Open Access Journals (Sweden)

    Shabani Naim

    2010-11-01

    Full Text Available Abstract Background Inhibins are important regulators of the female reproductive system. Recently, two new inhibin subunits betaC and betaE have been described, although it is unclear if they are synthesized in normal human endometrium. Methods Samples of human endometrium were obtained from 82 premenopausal, non-pregnant patients undergoing gynecological surgery for benign diseases. Endometrium samples were classified according to anamnestic and histological dating into proliferative (day 1-14, n = 46, early secretory (day 15-22, n = 18 and late secretory phase (day 23-28, n = 18. Immunohistochemical analyses were performed with specific antibodies against inhibin alpha (n = 81 as well as inhibin betaA (n = 82, betaB (n = 82, betaC (n = 74 and betaE (n = 76 subunits. RT-PCR was performed for all inhibin subunits. Correlation was assessed with the Spearman factor to assess the relationship of inhibin-subunits expression within the different endometrial samples. Results The novel inhibin betaC and betaE subunits were found in normal human endometrium by immunohistochemical and molecular techniques. Inhibin alpha, betaA, betaB and betaE subunits showed a circadian expression pattern, being more abundant during the late secretory phase than during the proliferative phase. Additionally, a significant correlation between inhibin alpha and all inhibin beta subunits was observed. Conclusions The differential expression pattern of the betaC- and betaE-subunits in normal human endometrial tissue suggests that they function in endometrial maturation and blastocyst implantation. However, the precise role of these novel inhibin/activin subunits in human endometrium is unclear and warrants further investigation.

  10. Immunization with the conjugate vaccine Vi-CRM₁₉₇ against Salmonella typhi induces Vi-specific mucosal and systemic immune responses in mice.

    Science.gov (United States)

    Fiorino, Fabio; Ciabattini, Annalisa; Rondini, Simona; Pozzi, Gianni; Martin, Laura B; Medaglini, Donata

    2012-09-21

    Typhoid fever is a public health problem, especially among young children in developing countries. To address this need, a glycoconjugate vaccine Vi-CRM₁₉₇, composed of the polysaccharide antigen Vi covalently conjugated to the non-toxic mutant of diphtheria toxin CRM₁₉₇, is under development. Here, we assessed the antibody and cellular responses, both local and systemic, following subcutaneous injection of Vi-CRM₁₉₇. The glycoconjugate elicited Vi-specific serum IgG titers significantly higher than unconjugated Vi, with prevalence of IgG1 that persisted for at least 60 days after immunization. Vi-specific IgG, but not IgA, were present in intestinal washes. Lymphocytes proliferation after restimulation with Vi-CRM₁₉₇ was observed in spleen and mesenteric lymph nodes. These data confirm the immunogenicity of Vi-CRM₁₉₇ and demonstrate that the vaccine-specific antibody and cellular immune responses are present also in the intestinal tract, thus strengthening the suitability of Vi-CRM₁₉₇ as a promising candidate vaccine against Salmonella Typhi. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Characterization of Citrobacter sp. line 328 as a source of Vi for a Vi-CRM(197) glycoconjugate vaccine against Salmonella Typhi.

    Science.gov (United States)

    Rondini, Simona; Micoli, Francesca; Lanzilao, Luisa; Pisoni, Ivan; Di Cioccio, Vito; Saul, Allan J; Martin, Laura B

    2012-11-26

    Salmonella enterica serovar Typhi is the causative agent of typhoid fever with over 22 million cases and over 200,000 deaths reported annually. A vaccine is much needed for use in young children and the Novartis Vaccines Institute for Global Health (NVGH) is developing a conjugate vaccine which targets S. Typhi Vi capsular polysaccharide. Here we describe a method suitable for industrial scale production of the Vi antigen based on expression by a Citrobacter line. We optimized the production of Vi by selecting a suitable Citrobacter strain (Citrobacter 328) that yields high and stable expression of Vi in chemically defined medium under industrial-scale fermentation conditions. Vi-CRM197 made using Vi from Citrobacter 328 elicited high anti-Vi antibody levels in mice and rabbits. Citrobacter 328 is a suitable strain for production of Vi for conjugate anti-Typhi vaccines. Being a BSL-1 organism, which grows in defined medium and stably produces high yields of Vi, it offers excellent potential for safe production of inexpensive vaccines for populations at risk of typhoid fever.

  12. Plant and algal interference in bacterial beta-D-galactosidase and beta-D-glucuronidase assays.

    OpenAIRE

    Davies, C M; Apte, S C; Peterson, S M; Stauber, J L

    1994-01-01

    Several commonly occurring freshwater and marine plants and algae were screened for beta-D-galactosidase and beta-D-glucuronidase activities by using a 60-min enzyme assay based on the hydrolysis by these enzymes of 4-methylumbelliferyl-beta-D-galactoside and 4-methylumbelliferyl- beta-glucuronide, respectively. All freshwater plant extracts tested showed beta-D-galactosidase activity several at relatively high levels, and a number also showed beta-D-glucuronidase activity. A number of the ma...

  13. Polymer based nanocomposites for the removal of Cr(VI) from water

    CSIR Research Space (South Africa)

    Setshedi, K

    2012-10-10

    Full Text Available .3 pH 2 pH 6 % R em ov al pH Feasibility test for Cr(VI) contaminated ground water and the effect of competing ions 100 ppm Cr(VI) sol. Nanocomposite + Cr(VI) sol 0 ppm Cr(VI) sol. 0 20 40 60 80 100 Q e( m g/ g) Cr 6+ Cr 6... nanocomposites for the removal of Cr(VI) from water Emerging Researcher Symposium Katlego Setshedi 10 October 2012 Outline ? CSIR 2012 Slide 2 ? Background ? Problem statement ? Health impacts ? Remedies ? Objectives ? Experimental procedure...

  14. Smart Beta or Smart Alpha

    DEFF Research Database (Denmark)

    Winther, Kenneth Lillelund; Steenstrup, Søren Resen

    2016-01-01

    Smart beta has become the flavor of the decade in the investment world with its low fees, easy access to rewarded risk premiums, and appearance of providing good investment results relative to both traditional passive benchmarks and actively managed funds. Although we consider it well documented...... that smart beta investing probably will do better than passive market capitalization investing over time, we believe many are coming to a conclusion too quickly regarding active managers. Institutional investors are able to guide managers through benchmarks and risk frameworks toward the same well......-documented smart beta risk premiums and still motivate active managers to avoid value traps, too highly priced small caps, defensives, etc. By constructing the equity portfolios of active managers that resemble the most widely used risk premiums, we show that the returns and risk-adjusted returns measures...

  15. Covariances of nuclear matrix elements for O{nu}{beta}{beta} decay

    Energy Technology Data Exchange (ETDEWEB)

    Fogli, G L; Rotunno, A M [Dipartimento Interateneo di Fisica ' Michelangelo Merlin' , Via Orabona 4, 70126 Bari (Italy); Lisi, E, E-mail: annamaria.rotunno@ba.infn.i [Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Via Orabona 4, 70126 Bari (Italy)

    2010-01-01

    Estimates of nuclear matrix elements (NME) for neutrinoless double beta decay (O{nu}{beta}{beta}) based on the quasiparticle random phase approximations (QRPA) are affected by theoretical uncertainties, which may play a dominant role in comparison with projected experimental errors of future O{nu}{beta}{beta} experiments. We discuss the estimated variances and covariances of NME of several candidate nuclei within the QRPA, focusing on the following aspects: 1) the comparison of O{nu}{beta}{beta} signals, or limits, in different nuclei; 2) the prospects for testing nonstandard O{nu}2{beta} mechanisms in future experiments.

  16. Diamond turning of Si and Ge single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Blake, P.; Scattergood, R.O.

    1988-12-01

    Single-point diamond turning studies have been completed on Si and Ge crystals. A new process model was developed for diamond turning which is based on a critical depth of cut for plastic flow-to-brittle fracture transitions. This concept, when combined with the actual machining geometry for single-point turning, predicts that {open_quotes}ductile{close_quotes} machining is a combined action of plasticity and fracture. Interrupted cutting experiments also provide a meant to directly measure the critical depth parameter for given machining conditions.

  17. Observation of diamond turned OFHC copper using Scanning Tunneling Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Grigg, D.A.; Russell, P.E.; Dow, T.A.

    1988-12-01

    Diamond turned OFHC copper samples have been observed within the past few months using the Scanning Tunneling Microscope. Initial results have shown evidence of artifacts which may be used to better understand the diamond turning process. The STM`s high resolution capability and three dimensional data representation allows observation and study of surface features unobtainable with conventional profilometry systems. Also, the STM offers a better quantitative means by which to analyze surface structures than the SEM. This paper discusses findings on several diamond turned OFHC copper samples having different cutting conditions. Each sample has been cross referenced using STM and SEM.

  18. APPLIANCE OF COMPETITORS TECHNIQUES IN LEADING THE SKIES IN TURNING

    Directory of Open Access Journals (Sweden)

    Rašid Hadžić

    2009-11-01

    Full Text Available Competitors techniques in skiing characterize driving on edges, without gliding in certain fazes of turning. Today that characteristic is more and more present in all di- scipline, (downhill, super G, giant slalom and slalom so we can talk about appliance of basic technique of leading skies on all disciplines, with differences in position of skies in amplitude of moving and frequencies of changes of edges. From that point of view we distinct three typical shape of moving in turning, which have mutual distinction in influence on ski loading, and that has influence on tur- ning line and acceleration or checking in certain fazes of turning.

  19. A Multi-Turn Measurement System for the CERN PS

    CERN Document Server

    Angoletta, Maria Elena

    2002-01-01

    Multi-turn beam position measurements on one or more pickups provide very important information needed to derive machine optics parameters. A variety of analyses is possible, such as determination of phase advance, detuning with amplitude, and most important, the exploration of phase space. In this paper we present a new multi-turn acquisition system for the CERN Proton Synchrotron based on a CompactPCI fast digitiser and a new general object-oriented visualisation and analysis tool for the acquired multi-turn data.

  20. The ontological turn meets the certainty of death.

    Science.gov (United States)

    McDonald, Maryon

    2017-08-01

    The 'ontological turn' involves some anthropological points of long standing but the approaches recently coordinated into this turn have been presented as a 'call to arms', as shaking up 'mono-realist singularities' and as inherently political. This fighting talk has no doubt made important contributions to anthropology and insights from the ontological turn can help in anthropological understandings of medical practices. However, this paper contends that this helpfulness is also limited and that a call to arms may be inappropriate. This point is made through an ethnographic understanding of medical concern about the diagnosis of death.

  1. Tungstate (VI) sorption on hematite: An in situ ATR-FTIR probe on the mechanism.

    Science.gov (United States)

    Rakshit, Sudipta; Sallman, Bryan; Davantés, Athénais; Lefèvre, Grégory

    2017-02-01

    Owing to the suspected toxicity and carcinogenicity of tungstate (VI) oxyanions [i.e. mono tungstate and several polytungstate, generally represented by W (VI)], the environmental fate of W (VI) has been widely studied. Sorption is regarded as a major mechanism by which W (VI) species are retained in the solid/water interface. Iron (hydr)oxides have been considered important environmental sinks for W (VI) species. Here we report sorption mechanisms of W (VI) on a common iron oxide mineral-hematite under environmentally relevant solution properties using in situ attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopic probes. Initial W (VI) loadings varied from 10 to 200 μM at fixed pH values ranged from 4.6 to 8.1. For pH envelop (pHs = 4.6, 5.0, 5.5, 6.0, 6.5, 7.5, and 8.1) experiments, fixed W (VI) concentrations (i.e. 10 & 200 μM) were used to understand the effects of pH. The results indicated that at acidic pH values (pH hematite surface and the strength of the interaction increases with decreasing pH. In addition, initial W (VI) concentration affected the sorption mechanisms of W (VI) on hematite. Our study will aid the molecular level understanding of W (VI) retention on iron oxide surfaces. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Type VI secretion delivers bacteriolytic effectors to target cells.

    Science.gov (United States)

    Russell, Alistair B; Hood, Rachel D; Bui, Nhat Khai; LeRoux, Michele; Vollmer, Waldemar; Mougous, Joseph D

    2011-07-20

    Peptidoglycan is the major structural constituent of the bacterial cell wall, forming a meshwork outside the cytoplasmic membrane that maintains cell shape and prevents lysis. In Gram-negative bacteria, peptidoglycan is located in the periplasm, where it is protected from exogenous lytic enzymes by the outer membrane. Here we show that the type VI secretion system of Pseudomonas aeruginosa breaches this barrier to deliver two effector proteins, Tse1 and Tse3, to the periplasm of recipient cells. In this compartment, the effectors hydrolyse peptidoglycan, thereby providing a fitness advantage for P. aeruginosa cells in competition with other bacteria. To protect itself from lysis by Tse1 and Tse3, P. aeruginosa uses specific periplasmically localized immunity proteins. The requirement for these immunity proteins depends on intercellular self-intoxication through an active type VI secretion system, indicating a mechanism for export whereby effectors do not access donor cell periplasm in transit.

  3. Charge separation sensitized by advanced II-VI semiconductor nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, David F. [Univ.of California, Merced, CA (United States)

    2017-04-11

    This proposal focuses on how the composition and morphology of pure and alloyed II-VI semiconductor heterostructures control their spectroscopic and dynamical properties. The proposed research will use a combination of synthesis development, electron microscopy, time-resolved electronic spectroscopy and modeling calculations to study these nanostructures. The proposed research will examine the extent to which morphology, compression due to lattice mismatch and alloy effects can be used to tune the electron and hole energies and the spectroscopic properties of II-VI heterojunctions. It will also use synthesis, optical spectroscopy and HRTEM to examine the role of lattice mismatch and hence lattice strain in producing interfacial defects, and the extent to which defect formation can be prevented by controlling the composition profile through the particles and across the interfaces. Finally, we will study the magnitude of the surface roughness in core/shell nanostructures and the role of shell thickness variability on the inhomogeneity of interfacial charge transfer rates.

  4. Hvad skal vi med Etisk Råd?

    DEFF Research Database (Denmark)

    Ploug, Thomas; Gjerris, Mickey

    2012-01-01

    Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder.......Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder....

  5. Uranium (Vi) sorption onto zirconium diphosphate chemically modified

    Energy Technology Data Exchange (ETDEWEB)

    Garcia G, N. [Universidad Autonoma del Estado de Mexico, Facultad de Quimica, Paseo Tollocan esquina Paseo Colon s/n, Toluca 50120, Estado de Mexico (Mexico); Ordonez R, E., E-mail: nidgg@yahoo.com.m [ININ, Carretera Mexico-Toluca s/n, Ocoyoacac 52750, Estado de Mexico (Mexico)

    2010-10-15

    This work deals with the uranium (Vi) speciation after sorption onto zirconium diphosphate (ZrP{sub 2}O{sub 7}) surface, hydrated and in a surface modified with organic acids. Oxalic and citric acids were chosen to modify the ZrP{sub 2}O{sub 7} surface because they have poly carboxylic groups and they mimic the organic matter in nature. Thus the interest of this work is to evaluate the uranium (Vi) sorption edge at different s ph values in natural and modified surfaces. The luminescence technique (fluorescence and phosphorescence, respectively) was used for the quantification and speciation of uranyl sorbed at the zirconium diphosphate interface. The fluorescence experiment, showed that adsorption of uranyl on surface of zirconium diphosphate tends to 100%. The speciation shows that there are different complexes in surface which were formed between zirconium diphosphate and uranyl, since it is produced a displacement of wavelength in fluorescence spectra of each system. (Author)

  6. vi-Strauss, Caduveo Body Painting and the Readymade

    DEFF Research Database (Denmark)

    Wiseman, Boris Nicholas Daniel

    2008-01-01

    The aim of this article is to explore some convergences between aesthetics and the anthropology of art, two disciplines often thought of as incompatible or mutually exclusive. Its impetus is the conviction that we have much to gain by a more systematic and concerted attempt at constituting an ethno......-aesthetics, i.e. a decentred aesthetics enriched by the dynamic of cross-cultural comparison. I will take as my starting point Lévi-Strauss's classic studies of Caduveo body painting and try to show how, beyond the clichés often repeated about structuralism, they provide valuable insights for an understanding...... of various forms of avant-garde art, from Duchamp's readymades, to Anthony Caro's abstract sculptures and assemblages by the Nouveau Réaliste artist Arman.  Although these forms of art would no doubt constitute, for Lévi-Strauss, instances of what he calls, pejoratively, an ‘academism of the signifier', I...

  7. A {beta} - {gamma} coincidence; Metodo de coincidencias {beta} - {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Agullo, F.

    1960-07-01

    A {beta} - {gamma} coincidence method for absolute counting is given. The fundamental principles are revised and the experimental part is detailed. The results from {sup 1}98 Au irradiated in the JEN 1 Swimming pool reactor are given. The maximal accuracy is 1 per cent. (Author) 11 refs.

  8. Snow Characterization Measurements from SNOW-TWO/Smoke Week VI,

    Science.gov (United States)

    1984-10-26

    Sum Symposium Itt (Barthel, vMoll SWW-T/SNMWI VI t * aX3 o, 1983) 1* Thi paper to concerned primarily with the presentation of data Barbara A. Noia ...thank& to Anthony Nat@9 and 3, erusoSnw]= a Morton clas OUSgt Domald MacDonald. tit, =7-0t, Haover, 22 AMlg -5 SSgt Dennis laCose, ad David Nalite &.4-4

  9. Rent ubehandlet grundvand - kan vi bevare drømmen?

    DEFF Research Database (Denmark)

    Arvin, Erik

    2016-01-01

    Vi drømmer om at drikke rent ubehandlet grundvand, et sundt naturprodukt uden menneskelig indgriben. Men kan drømmen opretholdes i vores komplicerede samfund, hvor alt skal være effektivt, og hvor der ikke må være kalkpletter på glasset? Jeg har arbejdet for rent drikkevand i mere end 30 år. Det...

  10. EXTRACTION DU Cr(VI PAR MEMBRANE POLYMERE A INCLUSION

    Directory of Open Access Journals (Sweden)

    O KEBICHE SENHADJI

    2008-06-01

    Le pH de la solution aqueuse constituant la phase source est un paramètre clé dans l’opération de transport du Cr(VI à travers les MPIs étudiées. Un pH de 1,2 est recommandé pour la réalisation de l’extraction dans les conditions optimales déterminées.

  11. Hvordan finder vi den gode jordbærsmag?

    DEFF Research Database (Denmark)

    Bech, Anne Catharina; Nielsen, Stig F.

    1997-01-01

    I denne artikel vil vi forsøge at belyse "jordbærsmag" fra forskellige synsvinkler, og komme med forslag til metoder der kan anvendes til at øge vores viden på området, således at det fremover bliver muligt at forsyne det danske marked med jordbær med gode smagsegenskaber. Ofte anvendes begrebet ...

  12. ENDF-201: ENDF/B-VI summary documentation

    Energy Technology Data Exchange (ETDEWEB)

    Rose, P.F. [comp.

    1991-10-01

    Responsibility for oversight of the ENDF/B Evaluated Nuclear Data file lies with the Cross Section Evaluation Working Group (CSEWG), which is comprised of representatives from various governmental and industrial laboratories in the United States. Individual evaluations are provided by scientists at several US laboratories, including significant contributions by scientists from all over the world. In addition, ENDF/B-VI includes for the first time complete evaluations for three materials that were provided from laboratories outside the US. All data are checked and reviewed by CSEWG, and the data file is maintained and issued by the National Nuclear Data Center at Brookhaven National Laboratory. The previous version of the library, ENDF/B-V, was issued in 1979, and two revisions to the data file were provided in subsequent years, the latest occurring in 1981. A total of 75 new or extensively modified neutron sublibrary evaluations are included in ENDF/B-VI, and are summarized in this document. One incident proton sublibrary is described for Fe{sup 56}. The remaining evaluations in ENDF/B-VI have been carried over from earlier versions of ENDF, and have been updated to reflect the new formats. The release of ENDF/B-VI was carried out between January and June of 1990, with groups of materials being released on ``tapes.`` Table 1 is an index to the evaluation summaries, and includes the material identification or MAT number, the responsible laboratory, and the ``tape`` number. These evaluations have been released without restrictions on their distribution or use.

  13. ENDF-201: ENDF/B-VI summary documentation

    Energy Technology Data Exchange (ETDEWEB)

    Rose, P.F. (comp.)

    1991-10-01

    Responsibility for oversight of the ENDF/B Evaluated Nuclear Data file lies with the Cross Section Evaluation Working Group (CSEWG), which is comprised of representatives from various governmental and industrial laboratories in the United States. Individual evaluations are provided by scientists at several US laboratories, including significant contributions by scientists from all over the world. In addition, ENDF/B-VI includes for the first time complete evaluations for three materials that were provided from laboratories outside the US. All data are checked and reviewed by CSEWG, and the data file is maintained and issued by the National Nuclear Data Center at Brookhaven National Laboratory. The previous version of the library, ENDF/B-V, was issued in 1979, and two revisions to the data file were provided in subsequent years, the latest occurring in 1981. A total of 75 new or extensively modified neutron sublibrary evaluations are included in ENDF/B-VI, and are summarized in this document. One incident proton sublibrary is described for Fe{sup 56}. The remaining evaluations in ENDF/B-VI have been carried over from earlier versions of ENDF, and have been updated to reflect the new formats. The release of ENDF/B-VI was carried out between January and June of 1990, with groups of materials being released on tapes.'' Table 1 is an index to the evaluation summaries, and includes the material identification or MAT number, the responsible laboratory, and the tape'' number. These evaluations have been released without restrictions on their distribution or use.

  14. The new geographic information system in ETVA VI.PE.

    Science.gov (United States)

    Xagoraris, Zafiris; Soulis, George

    2016-08-01

    ETVA VI.PE. S.A. is a member of the Piraeus Bank Group of Companies and its activities include designing, developing, exploiting and managing Industrial Areas throughout Greece. Inside ETVA VI.PE.'s thirty-one Industrial Parks there are currently 2,500 manufacturing companies established, with 40,000 employees and € 2.5 billion of invested funds. In each one of the industrial areas ETVA VI.PE guarantees the companies industrial lots of land (sites) with propitious building codes and complete infrastructure networks of water supply, sewerage, paved roads, power supply, communications, cleansing services, etc. The development of Geographical Information System for ETVA VI.PE.'s Industrial Parks started at the beginning of 1992 and consists of three subsystems: Cadastre, that manages the information for the land acquisition of Industrial Areas; Street Layout - Sites, that manages the sites sold to manufacturing companies; Networks, that manages the infrastructure networks (roads, water supply, sewerage etc). The mapping of each Industrial Park is made incorporating state-of-the-art photogrammetric, cartographic and surveying methods and techniques. Passing through the phases of initial design (hybrid GIS) and system upgrade (integrated Gis solution with spatial database), the system is currently operating on a new upgrade (integrated gIS solution with spatial database) that includes redesigning and merging the system's database schemas, along with the creation of central security policies, and the development of a new web GIS application for advanced data entry, highly customisable and standard reports, and dynamic interactive maps. The new GIS bring the company to advanced levels of productivity and introduce the new era for decision making and business management.

  15. Interaction of aerobic soil bacteria with plutonium(VI)

    Energy Technology Data Exchange (ETDEWEB)

    Panak, Petra J.; Nitsche, Heino

    2000-08-22

    We studied the interaction of Pu(VI) with Pseudomonas stutzeri ATCC 17588 and Bacillus sphaericus ATCC 14577, representatives of the main aerobic groups of soil bacteria present in the upper soil layers. The accumulation studies have shown that these soil bacteria accumulate high amounts of Pu(VI). The sorption efficiency toward Pu(VI) decreased with increasing biomass concentration due to increased agglomeration of the bacteria resulting in a decreased total surface area and number of available complexing groups. Spores of Bacillus sphaericus showed a higher biosorption than the vegetative cells at low biomass concentration which decreased significantly with increasing biomass concentration. At higher biomass concentrations (> 0.7 g/L), the vegetative cells of both strains and the spores of B. sphaericus showed comparable sorption efficiencies. Investigations on the pH dependency of the biosorption and extraction studies with 0.01 M EDTA solution have shown that the biosorption of plutonium is a reversible process and the plutonium is bound by surface complexation. Optical absorption spectroscopy showed that one third of the initially present Pu(VI) was reduced to Pu(V) after 24 hours. Kinetic studies and solvent extraction to separate different oxidation states of Pu after contact with the biomass provided further information on the yield and the kinetics of the bacteria-mediated reduction. Long-term studies showed that also 16% of Pu(IV) was formed after one month. The comparison of the amount of Pu(IV) formed during that time period with literature data of the Pu(V) disproportionation, indicated that the Pu(IV) seemed to be rather the result of the disproportionation of the formed Pu(V) than of a further microbial reduction.

  16. Implementation of MP_Lite for the VI Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Weiyi [Iowa State Univ., Ames, IA (United States)

    2001-01-01

    MP_Lite is a light weight message-passing library designed to deliver the maximum performance to applications in a portable and user friendly manner. The Virtual Interface (VI) architecture is a user-level communication protocol that bypasses the operating system to provide much better performance than traditional network architectures. By combining the high efficiency of MP_Lite and high performance of the VI architecture, they are able to implement a high performance message-passing library that has much lower latency and better throughput. The design and implementation of MP_Lite for M-VIA, which is a modular implementation of the VI architecture on Linux, is discussed in this thesis. By using the eager protocol for sending short messages, MP_Lite M-VIA has much lower latency on both Fast Ethernet and Gigabit Ethernet. The handshake protocol and RDMA mechanism provides double the throughput that MPICH can deliver for long messages. MP_Lite M-VIA also has the ability to channel-bonding multiple network interface cards to increase the potential bandwidth between nodes. Using multiple Fast Ethernet cards can double or even triple the maximum throughput without increasing the cost of a PC cluster greatly.

  17. Facet-Dependent Cr(VI) Adsorption of Hematite Nanocrystals.

    Science.gov (United States)

    Huang, Xiaopeng; Hou, Xiaojing; Song, Fahui; Zhao, Jincai; Zhang, Lizhi

    2016-02-16

    In this study, the adsorption process of Cr(VI) on the hematite facets was systematically investigated with synchrotron-based Cr K-edge extended X-ray absorption fine structure (EXAFS) spectroscopy, in situ attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, density-functional theory calculation, and surface complexation models. Structural model fitting of EXAFS spectroscopy suggested that the interatomic distances of Cr-Fe were, respectively, 3.61 Å for the chromate coordinated hematite nanoplates with exposed {001} facets, 3.60 and 3.30 Å for the chromate coordinated hematite nanorods with exposed {001} and {110} facets, which were characteristic of inner-sphere complexation. In situ ATR-FTIR spectroscopy analysis confirmed the presence of two inner-sphere surface complexes with C3ν and C2ν symmetry, while the C3ν and C2ν species were assigned to monodentate and bidentate inner-sphere surface complexes with average Cr-Fe interatomic distances of 3.60 and 3.30 Å, respectively. On the basis of these experimental and theoretical results, we concluded that HCrO4(-) as dominated Cr(VI) species was adsorbed on {001} and {110} facets in inner-sphere monodentate mononuclear and bidentate binuclear configurations, respectively. Moreover, the Cr(VI) adsorption performance of hematite facets was strongly dependent on the chromate complexes formed on the hematite facets.

  18. Skal vi have reklame-TV i Danmark?

    Directory of Open Access Journals (Sweden)

    Ole Prehn

    1989-08-01

    Full Text Available Under stor ståhej fik vi reklamer i 1987 (TV-Syd og året efter kom turen til næsten resten af Danmark. Seertallene lever endnu ikke op til lovens forudsætninger, og reklamesel- skabet (TVR har derfor blandet sig uhørt kraftigt i den offentlige debat om reklamernes placering og programlægningen. Dette stemmer ikke særlig godt med de vandtætte skodder mellem reklamer og programlægning, som politikerne havde lovet os. Hvilke yderligere løftebrud er nødvendige i frem- tiden, hvis vi skal have TV betalt via reklamer? Ole Prehn gennemgår de politiske forudsætninger, beregninger af de så- kaldte kontaktpriser for TV-reklame og seertallene. Han når frem til, at reklamestrukturen i TV langt fra har nået sit endelige udviklingsstade i Danmark. Vi har endnu reklame-TV til gode.

  19. Skal vi have reklame-TV i Danmark?

    Directory of Open Access Journals (Sweden)

    Ole Prehn

    1989-03-01

    Full Text Available Under stor ståhej fik vi reklamer i 1987 (TV-Syd og året efter kom turen til næsten resten af Danmark. Seertallene lever endnu ikke op til lovens forudsætninger, og reklamesel- skabet (TVR har derfor blandet sig uhørt kraftigt i den offentlige debat om reklamernes placering og programlægningen. Dette stemmer ikke særlig godt med de vandtætte skodder mellem reklamer og programlægning, som politikerne havde lovet os. Hvilke yderligere løftebrud er nødvendige i frem- tiden, hvis vi skal have TV betalt via reklamer? Ole Prehn gennemgår de politiske forudsætninger, beregninger af de så- kaldte kontaktpriser for TV-reklame og seertallene. Han når frem til, at reklamestrukturen i TV langt fra har nået sit endelige udviklingsstade i Danmark. Vi har endnu reklame-TV til gode.

  20. Characterization of uranium(VI) sorption by organobentonite

    Energy Technology Data Exchange (ETDEWEB)

    Majdan, Marek, E-mail: marek.jerzy@poczta.umcs.lublin.pl [Faculty of Chemistry, Maria Curie Sklodowska University, 20-031 Lublin (Poland); Pikus, Stanislaw; Gajowiak, Agnieszka; Gladysz-Plaska, Agnieszka [Faculty of Chemistry, Maria Curie Sklodowska University, 20-031 Lublin (Poland); Krzyzanowska, Halina; Zuk, Jerzy [Institute of Physics, Maria Curie Sklodowska University, 20-031 Lublin (Poland); Bujacka, Monika [Faculty of Chemistry, Maria Curie Sklodowska University, 20-031 Lublin (Poland)

    2010-06-15

    The U(VI) sorption on the bentonite modified by hexadecyltrimethylammonium bromide (HDTMA) was studied in the concentration range: 0.0001-0.001 mol/dm{sup 3} in the aqueous phase and in the pH range: 3-10. The experiments concerning the pH influence on the molar absorption coefficient c{sub b} of U(VI) in the bentonite phase showed that the species: UO{sub 2}{sup 2+}, UO{sub 2}(OH){sup +}, UO{sub 2}(OH){sub 2} UO{sub 2}(OH){sub 3}{sup -}, UO{sub 2}(OH){sub 4}{sup 2-}, (UO{sub 2}){sub 3}(OH){sub 5}{sup +}, (UO{sub 2}){sub 3}(OH){sub 7}{sup -}, present in the aqueous phase, are responsible for uranium sorption. Their sorption parameters K were determined and it is evident that for higher concentrations of HDTMA{sup +} cations in the bentonite phase, i.e. for b96-b157 bentonite, the presence of anionic species: UO{sub 2}(OH){sub 3}{sup -}, UO{sub 2}(OH){sub 4}{sup 2-}, and (UO{sub 2}){sub 3}(OH){sub 7}{sup -} in the aqueous phase results in the increase of U(VI) molar absorption coefficient c{sub b} in the sorbent phase.

  1. VI-14, a novel flavonoid derivative, inhibits migration and invasion of human breast cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Li, Fanni; Li, Chenglin; Zhang, Haiwei; Lu, Zhijian [State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009 (China); Li, Zhiyu; You, Qidong [Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009 (China); Lu, Na [State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009 (China); Guo, Qinglong, E-mail: anticancer_drug@yahoo.com.cn [State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009 (China)

    2012-06-01

    It has been well characterized that flavonoids possess pronounced anticancer potentials including anti-angiogenesis, anti-metastasis, and pro-apoptosis. Herein, we report, for the first time, that VI-14, a novel flavonoid derivative, possesses anti-cancer properties. The purpose of this study is to investigate the anti-migration and anti-invasion activities of VI-14 in breast cancer cells. Our data indicate that VI-14 inhibits adhesion, migration and invasion of MDA-MB-231 and MDA-MB-435 human breast cancer cells. MDA-MB-231 cells treated with VI-14 display reduced activities and expressions of ECM degradation-associated proteins including matrix metalloproteinase 2 (MMP-2) and 9 (MMP-9) at both the protein and mRNA levels. Meanwhile, VI-14 treatment induces an up-regulated expression of tissue inhibitor of metalloproteinase 1 (TIMP-1) and 2 (TIMP-2) in MDA-MB-231 cells. Western blotting results show that phosphorylation levels of critical components of the MAPK signaling pathway, including ERK, JNK and P38, are dramatically decreased in VI-14-treated MDA-MB-231 cells. Furthermore, treatment of VI-14 significantly decreases the nuclear levels and the binding ability of nuclear factor-kappa B (NF-κB) and activator protein-1 (AP-1). Taken together, our data suggest that VI-14 treatment suppresses migration and motility of breast cancer cells, and VI-14 may be a potential compound for cancer therapy. Highlights: ► We report for the first time that VI-14 possesses anti-cancer properties. ► VI-14 weakens the adhesion, migration and invasion of human breast cancer cells. ► VI-14 decreases the activities and expressions of MMP-2/9. ► VI-14 suppresses the phosphorylation levels of the MAPK signaling pathway. ► VI-14 decreases the nuclear levels and the binding ability of NF-κB and AP-1.

  2. [The diagnostic value of serum beta-hydroxybutyrate in diabetic ketosis or diabetic ketoacidosis].

    Science.gov (United States)

    Yang, Hui-Lan; Yuan, Gao-Pin; Deng, Hao; Chen, Cheng; Peng, Xi; An, Zhen-Mei

    2014-03-01

    To determine the diagnostic value of serum beta-hydroxybutyrate (betaOHB) in diabetic ketosis or diabetic ketoacidosis. We conducted a retrospective review of clinical data, in West China Hospital from May 2011 to May 2013, of 1 209 patients with non-ketosis diabetics (DM group), 262 patients with diabetic ketosis or diabetic ketoacidosis (DK/DKA group), and 480 healthy people undergoing routine medical examinations (normal control group). Logistic regression analyses and ROC curves were performed in determining the diagnostic value of betaOHB for DK/DKA. The level of serum betaOHB was much higher in the DK/DKA patients than that of the participants in the DM group and normal control group (P < 0.01). The serum betaOHB turned negative earlier than urine ketone (P < 0.01) in the DK/DKA patients. The logistic regression analysis indicated that betaOHB was one of the independent risk factors for DK/DKA. The betaOHB had an area under of 0.975 in ROC curve, with 1 mmol/L [sensitivity (Sen.) 85.1%, specificity (Spe.) 95. 3%, positive predictive value (PV+) 80.36%, negative predictive value (PV-) 96.89%] as a diagnostic point for DK/DKA and 0.66 mmol/L (Sen. 95%, Spe. 89.2%, PV+ 66.41%, PV- 99.9%) as a screening point. Diabetic patients with a level or higher than 1 mmol/L serum betaOHB can accurately predict DK/DKA. Patients with a level or lower than 0.66 mmol/L serum betaOHB are unlikely to have DK/DKA.

  3. Production of poly-(beta-hydroxybutyric-co-beta-hydroxyvaleric) acids.

    Science.gov (United States)

    Ramsay, B A; Lomaliza, K; Chavarie, C; Dubé, B; Bataille, P; Ramsay, J A

    1990-01-01

    Alcaligenes latus, Alcaligenes eutrophus, Bacillus cereus, Pseudomonas pseudoflava, Pseudomonas cepacia, and Micrococcus halodenitrificans were found to accumulate poly-(beta-hydroxybutyric-co-beta-hydroxyvaleric) acid [P(HB-co-HV)] copolymer when supplied with glucose (or sucrose in the case of A. latus) and propionic acid under nitrogen-limited conditions. A fed-batch culture of A. eutrophus produced 24 g of poly-beta-hydroxybutyric acid (PHB) liter-1 under ammonium limitation conditions. When the glucose feed was replaced with glucose and propionic acid during the polymer accumulation phase, 17 g of P(HB-co-HV) liter-1 was produced. The P(HB-co-HV) contained 5.0 mol% beta-hydroxyvaleric acid (HV). Varying the carbon-to-nitrogen ratio at a dilution rate of 0.15 h-1 in a chemostat culture of A. eutrophus resulted in a maximum value of 33% (wt/wt) PHB in the biomass. In comparison, A. latus accumulated about 40% (wt/wt) PHB in chemostat culture under nitrogen-limited conditions at the same dilution rate. When propionic acid was added to the first stage of a two-stage chemostat, A. latus produced 43% (wt/wt) P(HB-co-HV) containing 18.5 mol% HV. In the second stage, the P(HB-co-HV) increased to 58% (wt/wt) with an HV content of 11 mol% without further addition of carbon substrate. The HV composition in P(HB-co-HV) was controlled by regulating the concentration of propionic acid in the feed. Poly-beta-hydroxyalkanoates containing a higher percentage of HV were produced when pentanoic acid replaced propionic acid. PMID:2117877

  4. ANALYSIS OF CHIP FORMATION DURING HARD TURNING THROUGH ACOUSTIC EMISSION

    Directory of Open Access Journals (Sweden)

    Miroslav Neslušan

    2012-01-01

    Full Text Available The paper deals with analysis of chip formation and related aspects of the chip formation during turning hardened steel 100Cr6. The paper draws a comparison of some aspects of the chip formation between turning annealed and hardened roll bearing steel. The results of the analysis show that there is the formation of a segmented chip in the case of hard turning. Frequency of segmentation is very high. A conventional piezoelectric dynamometer limits the frequency response to about 3.5 kHz. On the other hand, the frequency of process fluctuation may by obtained by using accelerometers or acoustic emission. This paper reports about the dynamic character of cutting process when hard turning and correlation among the calculated segmentation frequencies and the experimental analysis.

  5. Models and Algorithms for Tracking Target with Coordinated Turn Motion

    Directory of Open Access Journals (Sweden)

    Xianghui Yuan

    2014-01-01

    Full Text Available Tracking target with coordinated turn (CT motion is highly dependent on the models and algorithms. First, the widely used models are compared in this paper—coordinated turn (CT model with known turn rate, augmented coordinated turn (ACT model with Cartesian velocity, ACT model with polar velocity, CT model using a kinematic constraint, and maneuver centered circular motion model. Then, in the single model tracking framework, the tracking algorithms for the last four models are compared and the suggestions on the choice of models for different practical target tracking problems are given. Finally, in the multiple models (MM framework, the algorithm based on expectation maximization (EM algorithm is derived, including both the batch form and the recursive form. Compared with the widely used interacting multiple model (IMM algorithm, the EM algorithm shows its effectiveness.

  6. State-of-the-Art Beta Detection and Dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    David M. Hamby

    2008-08-15

    The research funded by this NEER grant establishes the framework for a detailed understanding of the challenges in beta dosimetry, especially in the presence of a mixed radiation field. The work also stimulated the thinking of the research group which will lead to new concepts in digital signal processing to allow collection of detection signals and real-time analysis such that simultaneous beta and gamma spectroscopy can take place. The work described herein (with detail in the many publications that came out of this research) was conducted in a manner that provided dissertation and thesis topics for three students, one of whom was completely funded by this grant. The overall benefit of the work came in the form of a dramatic shift in signal processing that is normally conducted in analog pulse shape analysis. Analog signal processing was shown not to be feasible for this type of work; digital signal processing was a must. This, in turn, led the research team to a new understanding of pulse analysis, one in which expands the state-of-the-art in simultaneous beta and gamma spectroscopy with a single detector.

  7. Group ib organometallic chemistry. XXXIV. Thermal behaviour and chemical reactivity of tetranuclear Me2N-substituted diarypropenylcopper-copper anion (Vi2Cu4X2) and mixed diarylpropenyl/organocopper (Vi2Cu4R2) compounds

    NARCIS (Netherlands)

    Hoedt, R.W.M. ten; Koten, G. van; Noltes, J.G.

    1980-01-01

    Thermal decomposition of configurationally pure 1,2-diarylpropenylcopper compounds Z-Vi2CU4Br2 and Z-Vi2Cu4R2 [Vi = (2-Me2NC6H4)C=C(Me)-(C6H4Me-4), R = 2-Me2NC6H4 or 4-MeC6H4CC] predominantly results in the formation of ViH. In contrast, only dimers (ViVi) were formed on thermolysis of (Z-ViCu2OTf)η

  8. Extended phenotype: nematodes turn ants into bird-dispersed fruits

    DEFF Research Database (Denmark)

    Hughes, D P; Kronauer, D J C; Boomsma, J J

    2008-01-01

    A recent study has discovered a novel extended phenotype of a nematode which alters its ant host to resemble ripe fruit. The infected ants are in turn eaten by frugivorous birds that disperse the nematode's eggs.......A recent study has discovered a novel extended phenotype of a nematode which alters its ant host to resemble ripe fruit. The infected ants are in turn eaten by frugivorous birds that disperse the nematode's eggs....

  9. Performances of cutting fluids in turning. Vegetable based oil - RV

    DEFF Research Database (Denmark)

    Axinte, Dragos Aurelian; Belluco, Walter

    1999-01-01

    Scope of the present measurement campaign is the evaluation of the cutting fluid performance. The report presents the standard routine and the results obtained when turning stainless steel and brass with a commercial vegetable based oil called RV. The methods were developed to be applicable...... in normal workshop conditions using common equipment for turning as well as in a test laboratory. The evaluation tests can be carried out using the desired number of repetitions in terms of workpiece materials and tools....

  10. Performances of cutting fluids in turning. Mineral oil - RM

    DEFF Research Database (Denmark)

    Axinte, Dragos Aurelian; Belluco, Walter

    1999-01-01

    Scope of the present measurement campaign is the evaluation of the cutting fluid performance. The report presents the standard routine and the results obtained when turning stainless steel and brass with a commercial vegetable based oil called RM. The methods were developed to be applicable...... in normal workshop conditions using common equipment for turning as well as in a test laboratory. The evaluation tests can be carried out using the desired number of repetitions in terms of workpiece materials and tools....

  11. A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.

    Science.gov (United States)

    Aubert, Daniel F; Xu, Hao; Yang, Jieling; Shi, Xuyan; Gao, Wenqing; Li, Lin; Bisaro, Fabiana; Chen, She; Valvano, Miguel A; Shao, Feng

    2016-05-11

    Burkholderia cenocepacia is an opportunistic pathogen of the cystic fibrosis lung that elicits a strong inflammatory response. B. cenocepacia employs a type VI secretion system (T6SS) to survive in macrophages by disarming Rho-type GTPases, causing actin cytoskeletal defects. Here, we identified TecA, a non-VgrG T6SS effector responsible for actin disruption. TecA and other bacterial homologs bear a cysteine protease-like catalytic triad, which inactivates Rho GTPases by deamidating a conserved asparagine in the GTPase switch-I region. RhoA deamidation induces caspase-1 inflammasome activation, which is mediated by the familial Mediterranean fever disease protein Pyrin. In mouse infection, the deamidase activity of TecA is necessary and sufficient for B. cenocepacia-triggered lung inflammation and also protects mice from lethal B. cenocepacia infection. Therefore, Burkholderia TecA is a T6SS effector that modifies a eukaryotic target through an asparagine deamidase activity, which in turn elicits host cell death and inflammation through activation of the Pyrin inflammasome. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. NEUROPSYCHOLOGICAL PREDICTORS OF SAFETY IN URBAN LEFT-TURN SCENARIOS.

    Science.gov (United States)

    Dawson, Jeffrey D; Yu, Lixi; Chen, Kuan-Hua; Rusch, Michelle; Johnson, Amy M; Aksan, Nazan S; Sunda, Takashi; Hiramatsu, Machiko; Anderson, Steven W; Rizzo, Matthew

    2013-06-01

    Left turns at urban intersections can be dangerous, especially when views are obstructed or pedestrians are present. Impairments in driver vision, motor, and cognition functions may further increase left-turn risk. We examined this problem in a simulated environment that included left-turn scenarios to study the driving behaviors of 28 drivers, ages 37 to 88 years, six of whom had "Useful Field of View" (UFOV) impairments. Subjects also completed a battery of neuropsychological tests. The simulated drive included an urban section with six left turns in three types of scenarios: 1) a semi truck blocking the view of oncoming traffic, 2) a lead vehicle obstruction, and 3) a pedestrian crossing ahead of the turning driver. Results showed a mean (SD) of 1.46 (1.60) collisions per driver (range 0 to 7), 83% of which occurred at intersections with semi trucks. Far visual acuity, contrast sensitivity, UFOV, Mini Mental State Examination, Trail-Making Test Part B, the Wisconsin Card Sort task, and age were all associated with the total number of collisions (Pearson correlation magnitudes between 0.37 to 0.77; p-values<0.05). Spearman correlations were less significant. Findings indicate that visual obstruction by on oncoming semi-truck is a particularly dangerous left-turn situation.

  13. Fate and transport of uranium (VI) in weathered saprolite.

    Science.gov (United States)

    Kim, Young-Jin; Brooks, Scott C; Zhang, Fan; Parker, Jack C; Moon, Ji-Won; Roh, Yul

    2015-01-01

    Batch and column experiments were conducted to investigate sorption and transport of uranium (U) in the presence of saprolite derived from interbedded shale, limestone, and sandstone sequences. Sorption kinetics were measured at two initial concentrations (C0; 1, 10 μM) and three soil:solution ratios (Rs/w; 0.005, 0.25, 2 kg/L) at pH 4.5 (pH of the saprolite). The rate of U loss from solution (μmole/L/h) increased with increasing Rs/w. Uranium sorption exhibited a fast phase with 80% sorption in the first eight hours for all C0 and Rs/w values and a slow phase during which the reaction slowly approached (pseudo)equilibrium over the next seven days. The pH-dependency of U sorption was apparent in pH sorption edges. U(VI) sorption increased over the pH range 4-6, then decreased sharply at pH > 7.5. U(VI) sorption edges were well described by a surface complexation model using calibrated parameters and the reaction network proposed by Waite et al. (1994). Sorption isotherms measured using the same Rs/w and pH values showed a solids concentration effect where U(VI) sorption capacity and affinity decreased with increasing solids concentration. This effect may have been due to either particle aggregation or competition between U(VI) and exchangeable cations for sorption sites. The surface complexation model with calibrated parameters was able to predict the general sorption behavior relatively well, but failed to reproduce solid concentration effects, implying the importance of appropriate design if batch experiments are to be utilized for dynamic systems. Transport of U(VI) through the packed column was significantly retarded. Transport simulations were conducted using the reactive transport model HydroGeoChem (HGC) v5.0 that incorporated the surface complexation reaction network used to model the batch data. Model parameters reported by Waite et al. (1994) provided a better prediction of U transport than optimized parameters derived from our sorption edges. The

  14. Mucopolysaccharidosis VI in cats - clarification regarding genetic testing.

    Science.gov (United States)

    Lyons, Leslie A; Grahn, Robert A; Genova, Francesca; Beccaglia, Michela; Hopwood, John J; Longeri, Maria

    2016-07-02

    The release of new DNA-based diagnostic tools has increased tremendously in companion animals. Over 70 different DNA variants are now known for the cat, including DNA variants in disease-associated genes and genes causing aesthetically interesting traits. The impact genetic tests have on animal breeding and health management is significant because of the ability to control the breeding of domestic cats, especially breed cats. If used properly, genetic testing can prevent the production of diseased animals, causing the reduction of the frequency of the causal variant in the population, and, potentially, the eventual eradication of the disease. However, testing of some identified DNA variants may be unwarranted and cause undo strife within the cat breeding community and unnecessary reduction of gene pools and availability of breeding animals. Testing for mucopolysaccharidosis Type VI (MPS VI) in cats, specifically the genetic testing of the L476P (c.1427T>C) and the D520N (c.1558G>A) variants in arylsulfatase B (ARSB), has come under scrutiny. No health problems are associated with the D520N (c.1558G>A) variant, however, breeders that obtain positive results for this variant are speculating as to possible correlation with health concerns. Birman cats already have a markedly reduced gene pool and have a high frequency of the MPS VI D520N variant. Further reduction of the gene pool by eliminating cats that are heterozygous or homozygous for only the MPS VI D520N variant could lead to more inbreeding depression effects on the breed population. Herein is debated the genetic testing of the MPS VI D520N variant in cats. Surveys from different laboratories suggest the L476P (c.1427T>C) disease-associated variant should be monitored in the cat breed populations, particularly breeds with Siamese derivations and outcrosses. However, the D520N has no evidence of association with disease in cats and testing is not recommended in the absence of L476P genotyping. Selection

  15. Beta-carotene as antioxidant

    NARCIS (Netherlands)

    Bast, A.; Plas, R.M. van der; Berg, H. van den; Haenen, G.R.M.M.

    1996-01-01

    Objective: Beta-carotene has been shown to exhibit a good radical-trapping antioxidant activity in vitro. We were interested to see if dietary β-carotene in combination with various intake levels for vitamin A would also inhibit lipid peroxidation. Design: Sixty male Wistar rats received vitamin A

  16. Beta Cell Workshop 2013 Kyoto

    DEFF Research Database (Denmark)

    Heller, R Scott; Madsen, Ole D; Nielsen, Jens Høiriis

    2013-01-01

    The very modern Kyoto International Conference Center provided the site for the 8th workshop on Beta cells on April 23-26, 2013. The preceding workshops were held in Boston, USA (1991); Kyoto, Japan (1994); Helsingør, Denmark (1997); Helsinki, Finland (2003); El Perello, Spain (2006); Peebles...

  17. Abstraction Mechanisms in the BETA Programming Language

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun; Madsen, Ole Lehrmann; Møller-Pedersen, Birger

    1983-01-01

    The BETA programming language is developed as part of the BETA project. The purpose of this project is to develop concepts, constructs and tools in the field of programming and programming languages. BETA has been developed from 1975 on and the various stages of the language are documented in [BETA...... a]. The application area of BETA is programming of embedded as well as distributed computing systems. For this reason a major goal has been to develop constructs that may be efficiently implemented. Furthermore the BETA language is intended to have a few number of basic but general constructs....... It is then necessary that the abstraction mechanisms are powerful in order to define more specialized constructs. BETA is an object oriented language like SIMULA 67 ([SIMULA]) and SMALLTALK ([SMALLTALK]). By this is meant that a construct like the SIMULA class/subclass mechanism is fundamental in BETA. In contrast...

  18. Neutron Beta Decay Studies with Nab

    CERN Document Server

    Baeßler, S.; Alonzi, L.P.; Balascuta, S.; Barrón-Palos, L.; Bowman, J.D.; Bychkov, M.A.; Byrne, J.; Calarco, J.R.; Chupp, T.; Cianciolo, T.V.; Crawford, C.; Frlež, E.; Gericke, M.T.; Glück, F.; Greene, G.L.; Grzywacz, R.K.; Gudkov, V.; Harrison, D.; Hersman, F.W.; Ito, T.; Makela, M.; Martin, J.; McGaughey, P.L.; McGovern, S.; Page, S.; Penttilä, S.I.; Počanić, D.; Rykaczewski, K.P.; Salas-Bacci, A.; Tompkins, Z.; Wagner, D.; Wilburn, W.S.; Young, A.R.

    2012-01-01

    Precision measurements in neutron beta decay serve to determine the coupling constants of beta decay and allow for several stringent tests of the standard model. This paper discusses the design and the expected performance of the Nab spectrometer.

  19. How Do Beta Blocker Drugs Affect Exercise?

    Science.gov (United States)

    ... Aneurysm More How do beta blocker drugs affect exercise? Updated:Aug 22,2017 Beta blockers are a ... about them: Do they affect your ability to exercise? The answer can vary a great deal, depending ...

  20. The beta subunit of casein kinase II

    DEFF Research Database (Denmark)

    Boldyreff, B; Piontek, K; Schmidt-Spaniol, I

    1991-01-01

    cDNAs encoding the beta subunit of pig and mouse CKII were isolated. The porcine cDNA was expressed as a fusion protein in Escherichia coli and used for the production of anti-CKII-beta subunit specific antibodies.......cDNAs encoding the beta subunit of pig and mouse CKII were isolated. The porcine cDNA was expressed as a fusion protein in Escherichia coli and used for the production of anti-CKII-beta subunit specific antibodies....

  1. Microstructural analyses of Cr(VI) speciation in chromite ore processing Residue (COPR)

    Energy Technology Data Exchange (ETDEWEB)

    CHRYSOCHOOU, MARIA; FAKRA, SIRINE C .; Marcus, Matthew A.; Moon, Deok Hyun; Dermatas, Dimitris

    2010-03-01

    The speciation and distribution of Cr(VI) in the solid phase was investigated for two types of chromite ore processing residue (COPR) found at two deposition sites in the United States: gray-black (GB) granular and hard brown (HB) cemented COPR. COPR chemistry and mineralogy were investigated using micro-X-ray absorption spectroscopy and micro-X-ray diffraction, complemented by laboratory analyses. GB COPR contained 30percent of its total Cr(VI) (6000 mg/kg) as large crystals(>20 ?m diameter) of a previously unreported Na-rich analog of calcium aluminum chromate hydrates. These Cr(VI)-rich phases are thought to be vulnerable to reductive and pH treatments. More than 50percent of the Cr(VI) was located within nodules, not easily accessible to dissolved reductants, and bound to Fe-rich hydrogarnet, hydrotalcite, and possibly brucite. These phases are stable over a large pH range, thus harder to dissolve. Brownmilleritewasalso likely associated with physical entrapment of Cr(VI) in the interior of nodules. HB COPR contained no Cr(VI)-rich phases; all Cr(VI) was diffuse within the nodules and absent from the cementing matrix, with hydrogarnet and hydrotalcite being the main Cr(VI) binding phases. Treatment ofHBCOPRis challenging in terms of dissolving the acidity-resistant, inaccessible Cr(VI) compounds; the same applies to ~;;50percent of Cr(VI) in GB COPR.

  2. Cr(VI) reduction by Bacillus coagulans isolated from contaminated soils

    Energy Technology Data Exchange (ETDEWEB)

    Philip, L.; Iyengar, L. [Indian Inst. of Tech., Kharagpur (India); Venkobachar, C. [Univ. of West Indies, St. Augustine (Trinidad and Tobago). Dept. of Civil Engineering

    1998-12-01

    Investigation on Cr(VI) reduction was conducted using bacteria isolated from soil samples receiving electroplating wastewater. Chromium reduction capacity of these isolates was compared with that of Pseudomonas aeruginosa, a pure culture procured from the Institute of Microbial Technology, as well as Bacillus circulans, a laboratory isolate from garden soil. Bacillus coagulans, isolated and identified from chromium polluted soil, gave maximum reduction potential among all organisms studied. Malate was found to yield maximum biotransformation out of four electron donors employed. B. coagulans was able to reduce Cr(VI) even at 10 mM initial Cr(VI) concentration. With an increase in initial cell density, Cr(VI) reduction capacity was also increased; however, maximum specific biotransformation occurred at low cell densities. The optimum pH for Cr(VI) reduction was 7. Sulphates and nitrates did not compete with Cr(VI) for accepting the electrons. The presence of respiratory inhibitors like DNP and NaN{sub 3} marginally reduced the Cr(VI) reduction capacity. Cell free extracts were able to reduce Cr(VI) even in the absence of external electron donors; however, marginal increase was found in the presence of malate, nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide. The contribution of cell membrane in Cr(VI) reduction was negligible. Hence, the soluble enzymes appear to be responsible for Cr(VI) reduction by B. coagulans.

  3. CHROMIUM(VI REDUCTION BY A MIXED CULTURE OF SULFATE REDUCING BACTERIA DEVELOPED IN COLUMN REACTOR

    Directory of Open Access Journals (Sweden)

    Cynthia Henny

    2008-03-01

    Full Text Available A lactate enriched mixed sulfate reducing bacteria (SRB culture was examined for the reduction of Cr(VI in a continuous flow system. The influent was mineral salts media added with lactate and sulfate with amounts of 8 and 6 mM respectively as electron donor and electron acceptor. The SRB culture was allowed to stabilize in the column before adding the Cr(VI to the influent. Chromium and sulfate reduction and lactate oxidation were examined by measuring the concentrations of Cr(Vl, sulfate and lactate in the influent and the effluent over time. The experiment was discontinued when Cr(VI concentration in the effiuent was breakthrough. In the absence of Cr(VI, sulfate was not completely reduced in the column, although lactate was completely oxidized and acetate as an intermediate product was not often detected. Almost all of Cr(VI loaded was reduced in the column seeded with the SRB culture at influent Cr(VI concentrations of 192,385 and769 mM. There was no significant Cr(VI loss in the control column, indicating that Cr(VI removal was due to the reduction of Cr(VI to Cr (lll by the SRB culture. The instantaneous Cr(VI removal decreased to a minimum of 32%, 24 days after the influent Cr(VI concentration was increased to 1540 mM, ancl sulfate removal efficiency decreased to a minimum of 17%. The SRB population in the column decreased 100 days after C(VI was added to the column. The total mass of Cr(VI reduced was approximately 878 mmol out of 881 mmol of Cr(Vl loaded in 116 days. The results clearly show that our developed SRB culture could reduced Cr(Vl considerably.

  4. New approach in modeling Cr(VI) sorption onto biomass from metal binary mixtures solutions

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Chang [College of Environmental Science and Engineering, Anhui Normal University, South Jiuhua Road, 189, 241002 Wuhu (China); Chemical Engineering Department, Escola Politècnica Superior, Universitat de Girona, Ma Aurèlia Capmany, 61, 17071 Girona (Spain); Fiol, Núria [Chemical Engineering Department, Escola Politècnica Superior, Universitat de Girona, Ma Aurèlia Capmany, 61, 17071 Girona (Spain); Villaescusa, Isabel, E-mail: Isabel.Villaescusa@udg.edu [Chemical Engineering Department, Escola Politècnica Superior, Universitat de Girona, Ma Aurèlia Capmany, 61, 17071 Girona (Spain); Poch, Jordi [Applied Mathematics Department, Escola Politècnica Superior, Universitat de Girona, Ma Aurèlia Capmany, 61, 17071 Girona (Spain)

    2016-01-15

    In the last decades Cr(VI) sorption equilibrium and kinetic studies have been carried out using several types of biomasses. However there are few researchers that consider all the simultaneous processes that take place during Cr(VI) sorption (i.e., sorption/reduction of Cr(VI) and simultaneous formation and binding of reduced Cr(III)) when formulating a model that describes the overall sorption process. On the other hand Cr(VI) scarcely exists alone in wastewaters, it is usually found in mixtures with divalent metals. Therefore, the simultaneous removal of Cr(VI) and divalent metals in binary mixtures and the interactive mechanism governing Cr(VI) elimination have gained more and more attention. In the present work, kinetics of Cr(VI) sorption onto exhausted coffee from Cr(VI)–Cu(II) binary mixtures has been studied in a stirred batch reactor. A model including Cr(VI) sorption and reduction, Cr(III) sorption and the effect of the presence of Cu(II) in these processes has been developed and validated. This study constitutes an important advance in modeling Cr(VI) sorption kinetics especially when chromium sorption is in part based on the sorbent capacity of reducing hexavalent chromium and a metal cation is present in the binary mixture. - Highlights: • A kinetic model including Cr(VI) reduction, Cr(VI) and Cr(III) sorption/desorption • Synergistic effect of Cu(II) on Cr(VI) elimination included in the model • Model validation by checking it against independent sets of data.

  5. Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors

    NARCIS (Netherlands)

    Brodde, O. E.; Zerkowski, H. R.; Borst, H. G.; Maier, W.; Michel, M. C.

    1989-01-01

    Cardiac beta-adrenoceptor density and subtype distribution has been determined in different kinds of heart failure. A decrease in cardiac beta-adrenoceptor function appears to be a general phenomenon in all kinds of heart failure. However, cardiac beta 1- and beta 2-adrenoceptors seem to be

  6. Polypeptides having beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same

    Science.gov (United States)

    Morant, Marc Dominique

    2014-05-06

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  7. Polypeptides having beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same

    Energy Technology Data Exchange (ETDEWEB)

    Morant, Marc Dominique

    2014-05-06

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  8. Polypeptides having beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same

    Energy Technology Data Exchange (ETDEWEB)

    Morant, Marc Dominique

    2014-04-29

    The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

  9. THE ALPHA/BETA-HYDROLASE FOLD

    NARCIS (Netherlands)

    OLLIS, DL; CHEAH, E; CYGLER, M; FROLOW, F; FRANKEN, SM; HAREL, M; REMINGTON, SJ; SILMAN, [No Value; SCHRAG, J; SUSSMAN, JL; VERSCHUEREN, KHG; GOLDMAN, A

    We have identified a new protein fold-the alpha/beta-hydrolase fold-that is common to several hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is similar: an alpha/beta-sheet, not barrel, of eight beta-sheets connected by alpha-helices. These

  10. Beta-lactamases in Enterobacteriaceae in broilers

    NARCIS (Netherlands)

    Dierikx, C.M.

    2013-01-01

    Resistance to cephalosprins due to the production of extended spectrum beta-lactamases (ESBLs) or plasmid mediated AmpC beta-lactamases is increasingly found in infections in humans outside the hospital. The genes encoding for these beta-lactamases are located on mobile DNA (plasmids), which can be

  11. Importance of c-Type cytochromes for U(VI reduction by Geobacter sulfurreducens

    Directory of Open Access Journals (Sweden)

    Leang Ching

    2007-03-01

    Full Text Available Abstract Background In order to study the mechanism of U(VI reduction, the effect of deleting c-type cytochrome genes on the capacity of Geobacter sulfurreducens to reduce U(VI with acetate serving as the electron donor was investigated. Results The ability of several c-type cytochrome deficient mutants to reduce U(VI was lower than that of the wild type strain. Elimination of two confirmed outer membrane cytochromes and two putative outer membrane cytochromes significantly decreased (ca. 50–60% the ability of G. sulfurreducens to reduce U(VI. Involvement in U(VI reduction did not appear to be a general property of outer membrane cytochromes, as elimination of two other confirmed outer membrane cytochromes, OmcB and OmcC, had very little impact on U(VI reduction. Among the periplasmic cytochromes, only MacA, proposed to transfer electrons from the inner membrane to the periplasm, appeared to play a significant role in U(VI reduction. A subpopulation of both wild type and U(VI reduction-impaired cells, 24–30%, accumulated amorphous uranium in the periplasm. Comparison of uranium-accumulating cells demonstrated a similar amount of periplasmic uranium accumulation in U(VI reduction-impaired and wild type G. sulfurreducens. Assessment of the ability of the various suspensions to reduce Fe(III revealed no correlation between the impact of cytochrome deletion on U(VI reduction and reduction of Fe(III hydroxide and chelated Fe(III. Conclusion This study indicates that c-type cytochromes are involved in U(VI reduction by Geobacter sulfurreducens. The data provide new evidence for extracellular uranium reduction by G. sulfurreducens but do not rule out the possibility of periplasmic uranium reduction. Occurrence of U(VI reduction at the cell surface is supported by the significant impact of elimination of outer membrane cytochromes on U(VI reduction and the lack of correlation between periplasmic uranium accumulation and the capacity for uranium

  12. Clusters of conserved beta cell marker genes for assessment of beta cell phenotype

    DEFF Research Database (Denmark)

    Martens, Geert A; Jiang, Lei; Hellemans, Karine H

    2011-01-01

    The aim of this study was to establish a gene expression blueprint of pancreatic beta cells conserved from rodents to humans and to evaluate its applicability to assess shifts in the beta cell differentiated state. Genome-wide mRNA expression profiles of isolated beta cells were compared to those...... microdissected beta cells, monitor adaptations of the beta cell phenotype to fasting, and retrieve possible conserved transcriptional regulators....

  13. Am(VI) Extraction Final Report: FY16

    Energy Technology Data Exchange (ETDEWEB)

    Mincher, Bruce Jay [Idaho National Lab. (INL), Idaho Falls, ID (United States); Grimes, Travis Shane [Idaho National Lab. (INL), Idaho Falls, ID (United States); Tillotson, Richard Dean [Idaho National Lab. (INL), Idaho Falls, ID (United States); Law, Jack Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    This report summarizes activities related to hexavalent Am extraction for FY16, in completion of FCR&D Milestone M3FT-16IN030103027. Activities concentrated on three areas of research: 1) centrifugal contactor hot testing, 2) Am(VI) stability studies, and 3) alternative oxidant studies. A brief summary of each task follows. Hot Testing: A new engineering-scale oxidation and solvent extraction test bed was built at Idaho National Laboratory to allow for solvent extraction testing of minor actinide separation concepts. The test bed consists of an oxidation vessel, filtration apparatus, four, 3D printed, 2-cm diameter centrifugal contactors, feed/product vessels, and sample ports. This system replaced the previous 3 stage, 5-cm contactor test bed that was used for the initial testing in FY14. In the FY16 hot test, a feed simulant was spiked with 243Am and 139Ce and treated with 60 g/L sodium bismuthate for two hours to oxidize the Am(III) to Am(VI). This solution was then pumped through a filter and into the four-stage centrifugal contactor setup. The organic phase solvent formulation was 1 M diethylhexylbutyramide (DEHBA)/dodecane. The test showed that Am(VI) was produced by bismuthate oxidation and the residual oxidant was successfully filtered without back pressure buildup. Sixty-four percent of Am was extracted in the contactors using DEHBA. Both Am and Ce were quantitatively stripped by 0.1 M H2O2. Successful demonstration of the utility of small, printable contactors suggests that hot testing of separations concepts can now be conducted more often, since it is cheaper, generates less waste, and entails much less radcon risk than previous testing. Am(VI) stability: A rigorous examination of reagents was conducted to determine if contaminants could interfere with Am oxidation and extraction. An series of DAm measurements showed that bismuthate particle size, water source, acid quality, and DAAP batch or pre-treatment had little effect on extraction efficiency

  14. Micro RNA-214 contributes to proteasome independent downregulation of beta catenin in Huntington's disease knock-in striatal cell model STHdhQ111/Q111.

    Science.gov (United States)

    Ghatak, Supratim; Raha, Sanghamitra

    2015-04-10

    Role of beta catenin in Huntington's disease (HD) is not clear. Previous studies on HD reported varied levels of beta catenin. In the present study we showed that beta catenin is post transcriptionally down-regulated in mutant huntingtin knock-in cell model STHdhQ111/Q111. This in turn leads to decreased level of wnt/beta catenin responsive genes. We observed that Gsk3beta or Gsk3beta (phospho Ser 9) is unaltered in HD and this down-regulation of beta catenin is independent of proteasomal degradation. Finally, we showed that the overexpression of miR-214 leads to the down-regulation of beta catenin at protein level only and reduces its transcriptional activity. We concluded that, miR-214 contributes to the processes that result in proteasome independent post transcriptional down-regulation of beta catenin in STHdhQ111/Q111, probably through inhibition of protein synthesis from beta catenin mRNA. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Coenzyme Q10 therapy in hereditary motor sensory neuropathy type VI with novel mitofusin 2 mutation.

    Science.gov (United States)

    Takahashi, Ryoichi; Ikeda, Tokuhei; Hamaguchi, Ayumi; Iwasa, Kazuo; Yamada, Masahito

    2012-01-01

    Hereditary motor sensory neuropathy type VI (HMSN VI) is hereditary neuropathy accompanied by optic neuropathy. The feasibility of Coenzyme Q10 (CoQ10) as a treatment for subacute visual impairment of HMSN VI was examined. A 37-year-old patient with HMSN VI with a novel mitofusin 2 mutation was treated with high dose of CoQ10 (200 mg/day) for eight months. Visual impairment was partially resolved after CoQ10 therapy. High dose CoQ10 therapy may improve the prognosis of subacute visual impairment in HMSN VI. To confirm the effectiveness of CoQ10 on HMSN VI, further studies are needed.

  16. Chlorine decay and trihalomethane formation following ferrate(VI) preoxidation and chlorination of drinking water.

    Science.gov (United States)

    Li, Cong; Luo, Feng; Dong, Feilong; Zhao, Jingguo; Zhang, Tuqiao; He, Guilin; Cizmas, Leslie; Sharma, Virender K

    2017-11-01

    This paper presents the effect of preoxidation with ferrate(VI) (FeVIO42-, Fe(VI)) prior to chlorination on chlorine decay and formation of disinfection by-products in filtered raw water from a full-scale drinking water treatment plant. The rate of chlorine decay became significantly faster as the concentration of ferrate(VI) increased. Chlorine degradation followed two first-order decay reactions with rate constants k1 and k2 for fast and slow decay, respectively. Kinetic modeling established the relationships between k1 and k2 and varying dosages of chlorine and ferrate(VI). When ferrate(VI) was used as a pre-oxidant, the levels of trihalomethanes (trichloromethane (TCM), dichlorobromomethane (DCBM), dibromochloromethane (DBCM), and tribromomethane (TBM)) in water samples decreased as the ferrate(VI) concentration increased. The concentrations of these trihalomethanes followed the order TCM > DCBM ≈ DBCM > TBM. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Specific Triazine Herbicides Induce Amyloid-beta(42) Production

    NARCIS (Netherlands)

    Portelius, Erik; Durieu, Emilie; Bodin, Marion; Cam, Morgane; Pannee, Josef; Leuxe, Charlotte; Mabondzo, Aloise; Oumata, Nassima; Galons, Herve; Lee, Jung Yeol; Chang, Young-Tae; Stuber, Kathrin; Koch, Philipp; Fontaine, Gaelle; Potier, Marie-Claude; Manousopoulou, Antigoni; Garbis, Spiros D.; Covaci, Adrian; Van Dam, Debby; De Deyn, Peter; Karg, Frank; Flajolet, Marc; Omori, Chiori; Hata, Saori; Suzuki, Toshiharu; Blennow, Kaj; Zetterberg, Henrik; Meijer, Laurent

    2016-01-01

    Proteolytic cleavage of the amyloid-beta protein precursor (A beta PP) ecretases leads to extracellular release of amyloid-beta (A beta) peptides. Increased production of A beta(42) over A beta(40) and aggregation into oligomers and plaques constitute an Alzheimer's disease (AD) hallmark.

  18. Wood Anatomy of the Neotropical Sapotaceae: VI. Chloroluma.

    Science.gov (United States)

    1978-01-01

    Chioroluma is the sixth in a series describing the anatomy of the secondary xylem of the neotropical Sapotaceae. The earlier papers , all by the same...W AUbS 034 FOREST PRODUCTS LAB MADISON W IS F/S 2/6WOOD ANATOMY OF itt ICOTROP ICAL SAPOTACEAE : V I. CI4LOROLUMAaU) 1978 B F Kt*AC I*A IMCLP...IFIED FSRP—FPt 330 Ml.. Dli Efr~ I -~~~~ p _____ ~~~~ -~~~~~~-‘ -~ - WOOD ANATOMY OF THE NEOTROPICAL SAPOTACEA~ VI. CHLOROLUMA RESEARCH PAPER FPL 330

  19. Thermoelectric properties of group VI metal silicide semiconductors

    Science.gov (United States)

    Nonomura, T.; Wen, C.; Kato, A.; Isobe, K.; Kubota, Y.; Nakamura, T.; Yamashita, M.; Hayakawa, Y.; Tatsuoka, H.

    The electrical and thermoelectric properties of group VI metal silicides, such as the Mo- and W-silicides as well as CrSi2, were investigated. The electronic band structures of the hexagonal- MoSi2, - WSi2 and CrSi2, were calculated using the first-principles total-energy calculation program in pseudopotential schemes with plane-wave basis functions, and their Seebeck coefficients were also calculated. In addition, the Mo- and W-silicides were synthesized using mechanical alloying followed by a spark plasma sintering technique, and their structural, electric and thermoelectric properties were examined.

  20. VI Olimpíada Brasileira de Astronomia

    Science.gov (United States)

    Canalle, J. B. G.; Villas da Rocha, J. F.; de Medeiros, J. R.; Wuensche de Souza, C. A.; da Silva, A. R.; Dottori, H. A.; Maia, M. A. G.; Poppe, P. C. R.; Martins, R. V.

    2004-04-01

    In this work we show the results of the VI Brazilian Olympiad of Astronomy, which took place on 17/05/2003 in all primary or secondary schools that previously registered. 76.445 students distributed over 1.565 schools from all Brazilian States took part in this event. A team of 5 students was selected to represent Brazil at the IX International Olympiad of Astronomy (IX IAO) in 2004. We participated of the VIII IAO that occurred in Stockholm, Sweden in 2003. Two of our students were awarded the bronze medal and silver medal in that event.

  1. Beta-blocking agents with vasodilating action.

    Science.gov (United States)

    Prichard, B N

    1992-01-01

    beta-Adrenoceptor-blocking drugs in current use can be separated into two main groups: those nonselective and those selective for beta 1-receptors. Members of each group reduce cardiac output and lead to an increase in peripheral resistance with a concomitant reduction in blood flow. beta-Blocking drugs not only may occupy the receptor preventing stimulation but also may have intrinsic sympathomimetic activity. Those with marked partial agonist activity at the beta 2-receptor giving some beta 2-mediated vasodilation can be regarded as the first multiple-action beta-blocking drugs. Subsequently, drugs have been developed that in addition to blocking the beta-receptor have an important peripheral vasodilator activity. Labetalol was the first drug of this group to be developed; prizidolol followed but has been withdrawn because of toxicity. Several other agents have been described, including bucindolol, carvedilol, celiprolol, dilevalol (one of the isomers of labetalol), and medroxolol. Three mechanisms have been reported to be responsible for peripheral vasodilation: alpha-receptor blockade, beta 2-agonism, and a dilator action independent of either the alpha- or beta-receptors. Evidence for these various mechanisms is more readily obtainable from animal experiments, but some confirmatory evidence has been obtained in humans. Inhibition of alpha-stimulation had been found with labetalol, medroxalol, and carvedilol and suggested with celiprolol. beta 2-Mediated vasodilation has been demonstrated by, for example, celiprolol and dilevalol; evidence of a vasodilation independent of alpha-blockade or beta 2-stimulation has been reported with celiprolol and carvedilol.

  2. Effect of transmitter turn-off time on transient soundings

    Science.gov (United States)

    Fitterman, D.V.; Anderson, W.L.

    1987-01-01

    A general procedure for computing the effect of non-zero turn-off time on the transient electromagnetic response is presented which can be applied to forward and inverse calculation methods for any transmitter-receiver configuration. We consider in detail the case of a large transmitter loop which has a receiver coil located at the center of the loop (central induction or in-loop array). For a linear turn-off ramp of width t0, the voltage response is shown to be the voltage due to an ideal step turn-off averaged over windows of width t0. Thus the effect is similar to that obtained by using averaging windows in the receiver. In general when time zero is taken to be the end of the ramp, the apparent resistivity increases for a homogeneous half-space over a limited time range. For time zero taken to be the start of the ramp the apparent resistivity is affected in the opposite direction. The effect of the ramp increases with increasing t0 and first-layer resistivity, is largest during the intermediate stage, and decreases with increasing time. It is shown that for a ramp turn-off, there is no effect in the early and late stages. For two-layered models with a resistive first layer (??1>??2), the apparent resistivity is increased in the intermediate stage. When the first layer is more conductive than the second layer (??1geoelectrical section on the turn-off effect. Neglecting the turn-off ramp will affect data interpretation as shown by field examples; the influence is the greatest on near-surface layer parameters. ?? 1987.

  3. Adsorption of Cr(VI) onto Hybrid Membrane of Carboxymethyl Chitosan and Silicon Dioxide

    OpenAIRE

    Yanling Deng; Naoki Kano; Hiroshi Imaizumi

    2017-01-01

    In this study, a new adsorbent material was synthesized by using carboxymethyl chitosan and silicon dioxide. The hybrid membrane was used as an adsorbent for the removal of Cr(VI) from aqueous solutions. The adsorption potential of Cr(VI) by the hybrid materials was investigated by varying experimental conditions such as pH, contact time, and the dosage of the hybrid membrane. Adsorption isotherms of Cr(VI) onto the hybrid membrane were studied with varying initial concentrations under optimu...

  4. Method for making graded I-III-VI.sub.2 semiconductors and solar cell obtained thereby

    Science.gov (United States)

    Devaney, Walter E.

    1987-08-04

    Improved cell photovoltaic conversion efficiencies are obtained by the simultaneous elemental reactive evaporation process of Mickelsen and Chen for making semiconductors by closer control of the evaporation rates and substrate temperature during formation of the near contact, bulk, and near junction regions of a graded I-III-VI.sub.2, thin film, semiconductor, such as CuInSe.sub.2 /(Zn,Cd)S or another I-III-VI.sub.2 /II-VI heterojunction.

  5. Visible light Cr(VI) reduction and organic chemical oxidation by TiO2 photocatalysis.

    Science.gov (United States)

    Sun, Bo; Reddy, Ettireddy P; Smirniotis, Panagiotis G

    2005-08-15

    Here we report the simultaneous Cr(VI) reduction and 4-chlorophenol (4-CP) oxidation in water under visible light (wavelength > 400 nm) using commercial Degussa P25 TiO2. This remarkable observation was attributed to a synergistic effect among TiO2, Cr(VI), and 4-CP. It is well known that TiO2 alone cannot remove either 4-CP or Cr(VI) efficiently under visible light. Moreover, the interaction between Cr(VI) and 4-CP is minimal if not negligible. However, we found that the combination of TiO2, Cr(VI), and 4-CP together can enable efficient Cr(VI) reduction and 4-CP oxidation under visible light. The specific roles of the three ingredients in the synergistic system were studied parametrically. It was found that optimal concentrations of Cr(VI) and TiO2 exist for the Cr(VI) reduction and 4-CP oxidation. Cr(VI) was compared experimentally with other metals such as Cu(ll), Fe(lll), Mn(IV), Ce(IV), and V(V). Among all these metal ions, only Cr(VI) promotes the photocatalytic oxidation of 4-CP. The amount of 4-CP removed was directly related to the initial concentration of Cr(VI). The system was also tested with four other chemicals (aniline, salicylic acid, formic acid, and diethyl phosphoramidate). We found that the same phenomenon occurred for organics containing acid and/or phenolic groups. Cr(VI) was reduced at the same time as the organic chemicals being oxidized during photoreaction under visible light. The synergistic effect was also found with pure anatase TiO2 and rutile TiO2. This study demonstrates a possible economical way for environmental cleanup under visible light.

  6. Removal of Cr(VI) and humic acid by using TiO2 photocatalysis.

    Science.gov (United States)

    Yang, Jae-Kyu; Lee, Seung-Mok

    2006-06-01

    The removal efficiencies of Cr(VI) and HA, using a TiO(2)-mediated photocatalytic process, were investigated with variations in the pH, TiO(2) dosage and Cr(VI)/HA ratio. During the photocatalytic reaction, the total removal of Cr(VI) occurred through adsorption onto TiO(2), as well as its reduction to Cr(III). However, oxidation and adsorption were identified as important removal processes for the treatment of HA. Due to the anionic type adsorption onto TiO(2) and its acid-catalyzed photocatalytic reduction, the removal of Cr(VI) decreased with increasing pH, while that of HA increased with increasing pH. The TiO(2) dosage was also an important parameter for the removal of Cr(VI). As the TiO(2) dosage was increased to 2.5 g l(-1), the removal of Cr(VI) was continuously enhanced, but decreased at dosages above 3 g l(-1) due to the increased blockage of the incident UV light used for the photocatalytic reaction. The removal of Cr(VI) was greatly enhanced when the system contained both HA and Cr(VI) compared to Cr(VI) alone. Also, the removal of HA was greatly enhanced when the system contained both HA and Cr(VI) compared to HA alone. The removal of Cr(VI) was continuously enhanced as the HA concentration gradually increased; however, no further increase was observed above 20 mg l(-1) HA due to the increased absorption of the UV light. This result supports that the photocatalytic reaction, with illuminated TiO(2), could be applied to more effectively treat wastewater containing both Cr(VI) and HA than that containing a single species only.

  7. Remediation of chromium-slag leakage with electricity cogeneration via a urea-Cr(VI) cell

    OpenAIRE

    Binbin Yu; Huimin Zhang; Wei Xu; Gang Li; Zucheng Wu

    2014-01-01

    Chromium pollution has been historically widespread throughout the world. Most available remediation technologies often require energy consumption. This study is aimed to develop electrochemical remediation for Cr(VI) in chromium-slag leakage with self-generated electricity. Dynamic leaching experiments of chromium-slag samples were conducted to survey the release and leaching behavior of Cr(VI). Based on previous work, a unique urea-Cr(VI) was designed, in which urea was employed as the fuel...

  8. Evaluation of cutting force uncertainty components in turning

    DEFF Research Database (Denmark)

    Axinte, Dragos Aurelian; Belluco, Walter; De Chiffre, Leonardo

    2000-01-01

    A procedure is proposed for the evaluation of those uncertainty components of a single cutting force measurement in turning that are related to the contributions of the dynamometer calibration and the cutting process itself. Based on an empirical model including errors form both sources......, the uncertainty for a single measurement of cutting force is presented, and expressions for the expected uncertainty vs. cutting parameters are proposed. This approach gives the possibility of evaluating cutting force uncertainty components in turning, for a defined range of cutting parameters, based on few...

  9. What happens when I turn on the TV set?

    OpenAIRE

    Nyre, Lars

    2007-01-01

    In a little known manuscript from 1998 Paddy Scannell asks some dumbfoundingly basic questions about the electronic media: ‘What happens when you turn on your television set? What is the meaning of television?’ The present article presents Scannell’s Heideggerian analysis of the act of turning on the TV set, and relates it to his other writings and lectures. The article doesn’t present Scannell’s work in its full breadth, but focuses on the technological dimension of mass communication. I als...

  10. Spatial turn and animation practices inspired by cultural anthropology

    Directory of Open Access Journals (Sweden)

    Agnieszka Wieszaczewska

    2016-09-01

    Full Text Available Spatial turn is one of the cultural turns, which have recently occurred in the humanities. It stresses the importance of issues such as space and place and can be successfully used as a theoretical perspective gaining use in thought over issues such as globalisation, transnationality, mapping but also education. In the discourses of pedagogical science space and place are considered through their multidimensional impact on education and learning. As significant concepts rooting pedagogy or pedagogy of borderland. The pedagogical reflection on space could be also used in the field of animation practices, especially in activities, which are related to place somehow colonised.

  11. A Cognitive Analysis of Truck Drivers’ Right-hand Turns

    DEFF Research Database (Denmark)

    Sieker, Tobias Grønborg; G. Skulason, Thorgeir; Sletting, Kristian

    2015-01-01

    This paper presents an investigation of truck drivers’ performance during right-hand turns performed in intersections with traffic lights in order to elicit the truck drivers’ domain, decision-making processes, and the strategies used while executing the turn. To gain knowledge about this, a truck...... driving instructor is interviewed, and four truck drivers are observed and interviewed. This results in a cognitive work analysis with the phases work domain analysis, control task analysis and strategies analysis. Through this study it is indicated that many different types of information are sought...

  12. Beta-thalassemia in Turkey.

    Science.gov (United States)

    Oner, R; Altay, C; Gurgey, A; Aksoy, M; Kilinç, Y; Stoming, T A; Reese, A L; Kutlar, A; Kutlar, F; Huisman, T H

    1990-01-01

    A review is presented of the various beta-thalassemia alleles observed in nearly 191 patients with beta-thalassemia major and their 182 heterozygous relatives. Determination was by gene amplification and dot-blot hybridization with synthetic probes, specific for 27 different mutations. Eighteen mutations have been observed; six of these account for nearly 83% of all thalassemia abnormalities. A new mutation, i.e. a G----C mutation at the acceptor splice site of IVS-I, was found in one teenager who was homozygous for this disease. The high consanguinity among the families was considered the main reason for the high number of patients with a homozygosity for the IVS-I-110 (G----A) mutation. Combinations of different mutations were present in many patients; some were mildly affected because of the specific mutation present on one chromosome. Combinations of classical beta-thalassemia and an abnormal hemoglobin mainly concerned Hb S. Hbs Knossos and Lepore were rare occurrences. A comparison of hematological data for adults with heterozygosities for some of the common alleles confirmed the low Hb A2 values in IVS-I-6 (T----C) heterozygotes and the high Hb F values for codon 8 (-AA), IVS-II-1 (G----A), and IVS-I-1 (G----A) heterozygotes.

  13. TOPICAL REVIEW: Double beta decay

    Science.gov (United States)

    Faessler, Amand; Simkovic, Fedor

    1998-12-01

    We review the recent developments in the field of nuclear double beta decay, which is presently an important topic in both nuclear and particle physics. The mechanism of lepton number violation within the neutrinoless double beta decay (0954-3899/24/12/001/img5-decay) is discussed in the context of the problem of neutrino mixing and the R-parity violating supersymmetric extensions of the standard model. The problem of reliable determination of the nuclear matrix elements governing both two-neutrino and neutrinoless modes of the double beta decay is addressed. The validity of different approximation schemes in the considered nuclear structure studies is analysed and the role of the Pauli exclusion principle for a correct treatment of nuclear matrix elements is emphasized. The constraints on different lepton-number violating parameters such as effective electron neutrino mass, effective right-handed weak interaction parameters, effective Majoron coupling constant and R-parity violating SUSY parameters are derived from the best presently available experimental limits on the half-life of 0954-3899/24/12/001/img5-decay.

  14. Human salivary carbonic anhydrase isoenzyme VI:physiology and association with the experience of dental caries

    OpenAIRE

    Kivelä, J.

    1999-01-01

    Abstract The carbonic anhydrases (CAs) participate in the maintenance of pH homeostasis in various tissues of the human body by catalyzing the reversible reaction CO2 + H2O ⇔ HCO3- + H+. Carbonic anhydrase isoenzyme VI (CA VI) is secreted into the human saliva by the serous acinar cells of the parotid and submandibular glands. The present work was undertaken in order to gain an understanding of the physiological role of CA VI in the oral cavity. CA VI concentrations were compared with ...

  15. Coenzyme Q10 Therapy in Hereditary Motor Sensory Neuropathy Type VI with Novel Mitofusin 2 Mutation

    OpenAIRE

    Takahashi, Ryoichi; Ikeda, Tokuhei; Hamaguchi, Ayumi; Iwasa, Kazuo; Yamada, Masahito

    2012-01-01

    Hereditary motor sensory neuropathy type VI (HMSN VI) is hereditary neuropathy accompanied by optic neuropathy. The feasibility of Coenzyme Q10 (CoQ10) as a treatment for subacute visual impairment of HMSN VI was examined. A 37-year-old patient with HMSN VI with a novel mitofusin 2 mutation was treated with high dose of CoQ10 (200 mg/day) for eight months. Visual impairment was partially resolved after CoQ10 therapy. High dose CoQ10 therapy may improve the prognosis of subacute visual impairm...

  16. Kinetics and Products of Chromium(VI) Reduction by Iron(II/III)-Bearing Clay Minerals.

    Science.gov (United States)

    Joe-Wong, Claresta; Brown, Gordon E; Maher, Kate

    2017-09-05

    Hexavalent chromium is a water-soluble pollutant, the mobility of which can be controlled by reduction of Cr(VI) to less soluble, environmentally benign Cr(III). Iron(II/III)-bearing clay minerals are widespread potential reductants of Cr(VI), but the kinetics and pathways of Cr(VI) reduction by such clay minerals are poorly understood. We reacted aqueous Cr(VI) with two abiotically reduced clay minerals: an Fe-poor montmorillonite and an Fe-rich nontronite. The effects of ionic strength, pH, total Fe content, and the fraction of reduced structural Fe(II) [Fe(II)/Fe(total)] were examined. The last variable had the largest effect on Cr(VI) reduction kinetics: for both clay minerals, the rate constant of Cr(VI) reduction varies by more than 3 orders of magnitude with Fe(II)/Fe(total) and is described by a linear free energy relationship. Under all conditions examined, Cr and Fe K-edge X-ray absorption near-edge structure spectra show that the main Cr-bearing product is a Cr(III)-hydroxide and that Fe remains in the clay structure after reacting with Cr(VI). This study helps to quantify our understanding of the kinetics of Cr(VI) reduction by Fe(II/III)-bearing clay minerals and may improve predictions of Cr(VI) behavior in subsurface environments.

  17. On the Stark broadening of Cr VI spectral lines in astrophysical plasma

    Science.gov (United States)

    Dimitrijević, M. S.; Simić, Z.; Sahal-Bréchot, S.

    2017-02-01

    Stark broadening parameters for Cr VI lines have been calculated using semiclassical perturbation method for conditions of interest for stellar plasma. Here are presented, as an example of obtained results, Stark broadening parameters for electron- and proton-impact broadening for Cr VI 4s 2S-4p 2P° λ = 1430 Å and Cr VI 4p 2P°-5s 2S λ = 611.8 Å multiplets. The obtained results are used to demonstrate the importance of Stark broadening of Cr VI in DO white dwarf atmospheres. Also the obtained results will enter in STARK-B database which is included in Virtual Atomic and Molecula Data Center - VAMDC.

  18. Polyaniline (PANI) modified bentonite by plasma technique for U(VI) removal from aqueous solution

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Xinghao [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Intelligent Manufacturing Technology Research Institute, Hefei University of Technology, Hefei 230088 (China); Cheng, Cheng [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Xiao, Chengjian, E-mail: xiaocj@caep.cn [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Shao, Dadong, E-mail: shaodadong@126.com [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Xu, Zimu, E-mail: xzm@mail.ustc.edu.cn [Intelligent Manufacturing Technology Research Institute, Hefei University of Technology, Hefei 230088 (China); Wang, Jiaquan; Hu, Shuheng [Intelligent Manufacturing Technology Research Institute, Hefei University of Technology, Hefei 230088 (China); Li, Xiaolong; Wang, Weijuan [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China)

    2017-07-31

    Highlights: • PANI/bentonie can be synthesized by simple plasma technique. • PANI/bentonie has an excellent adsorption capacity for trace uranium in solution. • U(VI) adsorption on PANI/bentonite is a spontaneous and endothermic process. - Abstract: Polyaniline (PANI) modified bentonite (PANI/bentonie) was synthesized by plasma induced polymerization of aniline on bentonite surface, and applied to uptake of uranium(VI) ions from aqueous solution. The as-synthesized PANI/bentonie was characterized by scanning electron microscopy (SEM), powder X-ray diffraction (XRD), thermal gravimetric analysis (TGA), and X-ray photoelectron spectroscopy (XPS). Batch adsorption technique was utilized to investigate the adsorption of U(VI) on bentonite and PANI/bentonite. The adsorption of U(VI) (10 mg/L) on PANI/bentonite surface is fairly depend on solution pH, ionic strength, and temperature in solution. The modified PANI on PANI/bentonite surface significantly enhances its adsorption capability for U(VI). The presence of humic acid (HA) can sound enhance U(VI) adsorption on PANI/bentonite at pH < 6.5 because of the strong complexation, and inhibits U(VI) adsorption at pH > 6.5. According to the thermodynamic parameters, the adsorption of U(VI) on PANI/bentonite surface is a spontaneous and endothermic process. The results highlight the application of PANI/bentonite composites as candidate material for the uptake of trace U(VI) from aqueous solution.

  19. VI-14, a novel flavonoid derivative, inhibits migration and invasion of human breast cancer cells.

    Science.gov (United States)

    Li, Fanni; Li, Chenglin; Zhang, Haiwei; Lu, Zhijian; Li, Zhiyu; You, Qidong; Lu, Na; Guo, Qinglong

    2012-06-01

    It has been well characterized that flavonoids possess pronounced anticancer potentials including anti-angiogenesis, anti-metastasis, and pro-apoptosis. Herein, we report, for the first time, that VI-14, a novel flavonoid derivative, possesses anti-cancer properties. The purpose of this study is to investigate the anti-migration and anti-invasion activities of VI-14 in breast cancer cells. Our data indicate that VI-14 inhibits adhesion, migration and invasion of MDA-MB-231 and MDA-MB-435 human breast cancer cells. MDA-MB-231 cells treated with VI-14 display reduced activities and expressions of ECM degradation-associated proteins including matrix metalloproteinase 2 (MMP-2) and 9 (MMP-9) at both the protein and mRNA levels. Meanwhile, VI-14 treatment induces an up-regulated expression of tissue inhibitor of metalloproteinase 1 (TIMP-1) and 2 (TIMP-2) in MDA-MB-231 cells. Western blotting results show that phosphorylation levels of critical components of the MAPK signaling pathway, including ERK, JNK and P38, are dramatically decreased in VI-14-treated MDA-MB-231 cells. Furthermore, treatment of VI-14 significantly decreases the nuclear levels and the binding ability of nuclear factor-kappa B (NF-κB) and activator protein-1 (AP-1). Taken together, our data suggest that VI-14 treatment suppresses migration and motility of breast cancer cells, and VI-14 may be a potential compound for cancer therapy. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Cr(III) reactivity and foot dermatitis in Cr(VI) positive patients

    DEFF Research Database (Denmark)

    Hansen, Malene Barré; Menné, Torkil; Johansen, Jeanne Duus

    2006-01-01

    Chromium allergy has become synonymous with Cr(VI) allergy. However, real exposure to chromium from leather products may include both Cr(III) and Cr(VI). In this study, we investigate the reactivity to both Cr(VI) and Cr(III) in consecutive patients to analyse the relation between foot eczema......(VI), of which 31 also had a positive Cr(III) reaction. No Cr(VI) negative patients had a positive reaction to Cr(III). An increased risk of foot dermatitis was found in Cr(VI) positive patients with a concomitant positive or doubtful reaction to Cr(III) compared with Cr(VI) positive patients with no reactions...... to Cr(III). The increased risk was not due to a higher degree of sensitivity to Cr(VI). Leather was reported most frequently as the suspected cause of chromium dermatitis (54%). However, Cr(VI) allergics having foot eczema and positive or doubtful Cr(III) reactions often had positive reactions to other...

  1. Role of paramagnetic chromium in chromium(VI)-induced damage in cultured mammalian cells.

    OpenAIRE

    Sugiyama, M

    1994-01-01

    Chromium(VI) compounds are known to be potent toxic and carcinogenic agents. Because chromium(VI) is easily taken up by cells and is subsequently reduced to chromium(III), the formation of paramagnetic chromium such as chromium(V) and chromium(III) is believed to play a role in the adverse biological effects of chromium(VI) compounds. The present report, uses electron spin resonance (ESR) spectroscopy; the importance of the role of paramagnetic chromium in chromium(VI)-induced damage in intac...

  2. Comparison of U(VI) adsorption onto nanoscale zero-valent iron and red soil in the presence of U(VI)–CO{sub 3}/Ca–U(VI)–CO{sub 3} complexes

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zhibin [Key Laboratory of Radioactive Geology and Exploration Technology Fundamental Science for National Defense, East China Institute of Technology, Nanchang 330013 (China); State Key Laboratory Breeding Base of Nuclear Resources and Environment (East China Institute of Technology), Ministry of Education, Nanchang 330013 (China); Chemistry, Biological and Materials Sciences Department, East China Institute of Technology, Nanchang 330013 (China); Liu, Jun [State Key Laboratory Breeding Base of Nuclear Resources and Environment (East China Institute of Technology), Ministry of Education, Nanchang 330013 (China); Cao, Xiaohong, E-mail: xhcao@ecit.cn [Key Laboratory of Radioactive Geology and Exploration Technology Fundamental Science for National Defense, East China Institute of Technology, Nanchang 330013 (China); State Key Laboratory Breeding Base of Nuclear Resources and Environment (East China Institute of Technology), Ministry of Education, Nanchang 330013 (China); Chemistry, Biological and Materials Sciences Department, East China Institute of Technology, Nanchang 330013 (China); Luo, Xuanping [Chemistry, Biological and Materials Sciences Department, East China Institute of Technology, Nanchang 330013 (China); Hua, Rong; Liu, Yan [Key Laboratory of Radioactive Geology and Exploration Technology Fundamental Science for National Defense, East China Institute of Technology, Nanchang 330013 (China); State Key Laboratory Breeding Base of Nuclear Resources and Environment (East China Institute of Technology), Ministry of Education, Nanchang 330013 (China); Chemistry, Biological and Materials Sciences Department, East China Institute of Technology, Nanchang 330013 (China); Yu, Xiaofeng; He, Likai [Chemistry, Biological and Materials Sciences Department, East China Institute of Technology, Nanchang 330013 (China); and others

    2015-12-30

    Highlights: • NZVI can be used for adsorbing U(VI)–CO{sub 3} complexes. • Use of NZVI is feasible for remediation of uranium-contaminated soils. • The mechanism of U(VI)–CO{sub 3} complexes adsorbing onto NZVI has been explained. - Abstract: The influence of U(VI)–CO{sub 3} and Ca–U(VI)–CO{sub 3} complexes on U(VI) adsorption onto red soil and nanoscale zero-valent iron (NZVI) was investigated using batch adsorption and fixed-bed column experiments to simulate the feasibility of NZVI as the reactive medium in permeable- reactive barriers (PRB) for in situ remediation of uranium-contaminated red soils. The adsorption capacity (q{sub e}) and distribution constant (K{sub d}) of NZVI and red soil decreased with increasing pH, dissolved carbonate and calcium concentrations, but the q{sub e} and K{sub d} values of NZVI were 5–10 times higher than those of red soil. The breakthrough pore volume (PV) values increased with the decrease of pH, dissolved carbonate and calcium concentration; however, the breakthrough PV values of the PRB column filled with 5% NZVI were 2.0–3.5 times higher than the 100% red soil column. The U(VI)–CO{sub 3} complexes adsorbed onto the surface of red soil/NZVI (≡SOH) to form SO–UO{sub 2}CO{sub 3}{sup −} or SO–UO{sub 2} (CO{sub 3}){sub 2}{sup 3−}. XPS and XRD analysis further confirmed the reduction of U(VI) to U(IV) and the formation of FeOOH on NZVI surfaces. The findings of this study are significant to the remediation of uranium-contaminated red soils and the consideration of practical U(VI) species in the natural environment.

  3. A simple Cr(VI)–S(IV)–O{sub 2} system for rapid and simultaneous reduction of Cr(VI) and oxidative degradation of organic pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Yanan; Yang, Shaojie [Department of Environmental Science, Hubei Key Lab of Biomass Resource Chemistry and Environmental Biotechnology, School of Resources and Environmental Science, Wuhan University, 430079 (China); Zhou, Danna, E-mail: zdncug@163.com [Faculty of Material Science and Chemistry, China University of Geosciences, Wuhan 430074 (China); Wu, Feng [Department of Environmental Science, Hubei Key Lab of Biomass Resource Chemistry and Environmental Biotechnology, School of Resources and Environmental Science, Wuhan University, 430079 (China)

    2016-04-15

    Highlights: • Rapid and simultaneous reduction of Cr(VI) and degradation of organic pollutants occur. • Oxysulfur radicals generated in Cr(VI)–S(IV)–O{sub 2} system oxidize the organic pollutants. • Acidic pH facilitates the reactions from both directions of reduction and oxidation. • Degradation potential of aromatic amines depends on the substituted groups. • Cr(VI)–S(IV)–O{sub 2} system is promising for “waste control by waste”. - Abstract: Hexavalent chromium (Cr(VI)), a heavy-metal contaminant, can be easily reduced to less toxic trivalent chromium (Cr(III)) by sulfite ions (S(IV)). However, S(IV) has not drawn as much attention as the ferrous ion has. We report herein a novel Cr(VI)–S(IV)–O{sub 2} system containing sulfite ions that rapidly and simultaneously reduces Cr(VI) and oxidize organic pollutants in the presence of oxygen in aqueous solutions. This Cr(VI)–S(IV)-O{sub 2} system contains the initiator Cr(VI), the reductant S(IV), and the oxidant O{sub 2}, which produce oxysulfur radicals (mainly SO{sub 4}·{sup −} and SO{sub 5}·{sup −}) and hydroxyl radicals (OH·). The Cr(VI)/S(IV) molar ratio, pH, and oxygen content play important roles in the entire reaction system. Acidic conditions (pH 3.0) facilitated degradation of organic compounds and reduction of Cr(VI) as well. In addition, experiments of rapid degradation of several kinds of organic pollutants such as azo dye (acid orange 7, AO7), aniline, phenol, bisphenol A etc were also conducted. Preliminary results show that the removal rates of the analogs of phenols or aromatic amines in this Cr(VI)–S(IV)–O{sub 2} system have a relationship with the electronic parameters (Hammett constant, σ) of the substituted groups. Thus, the Cr(VI)–S(IV)–O{sub 2} system, provides an excellent strategy of “waste control by waste” for removing multiple industrial contaminants.

  4. Effect of different solutes, natural organic matter, and particulate Fe(III) on ferrate(VI) decomposition in aqueous solutions.

    Science.gov (United States)

    Jiang, Yanjun; Goodwill, Joseph E; Tobiason, John E; Reckhow, David A

    2015-03-03

    This study investigated the impacts of buffer ions, natural organic matter (NOM), and particulate Fe(III) on ferrate(VI) decomposition and characterized Fe(VI) decomposition kinetics and exposure in various waters. Homogeneous and heterogeneous Fe(VI) decomposition can be described as a second- and first-order reaction with respect to Fe(VI), respectively. Fe(VI) decay was catalyzed by Fe(VI) decomposition products. Solutes capable of forming complexes with iron hydroxides retarded Fe(VI) decay. Fractionation of the resulting solutions from Fe(VI) self-decay and ferric chloride addition in borate- and phosphate-buffered waters showed that phosphate could sequester Fe(III). The nature of the iron precipitate from Fe(VI) decomposition was different from that of freshly precipitated ferric hydroxide from ferric chloride solutions. The stabilizing effects of different solutes on Fe(VI) are in the following order: phosphate > bicarbonate > borate. The constituents of colored and alkaline waters (NOM and bicarbonate) inhibited the catalytic effects of Fe(VI) decomposition products and stabilized Fe(VI) in natural waters. Because of the stabilizing effects of solutes, moderate doses of Fe(VI) added to natural waters at pH 7.5 resulted in exposures that have been shown to be effective for inactivation of target pathogens. Preformed ferric hydroxide was less effective than freshly dosed ferric chloride in accelerating Fe(VI) decomposition.

  5. Energy levels and radiative rates for transitions in Ti VI

    Science.gov (United States)

    Aggarwal, K. M.; Keenan, F. P.; Msezane, A. Z.

    2013-08-01

    We report on calculations of energy levels, radiative rates, oscillator strengths and line strengths for transitions among the lowest 253 levels of the (1s22s22p6) 3s23p5, 3s3p6, 3s23p43d, 3s3p53d, 3s23p33d2, 3s23p44s, 3s23p44p and 3s23p44d configurations of Ti VI. The general-purpose relativistic atomic structure package and flexible atomic code are adopted for the calculations. Radiative rates, oscillator strengths and line strengths are reported for all electric dipole (E1), magnetic dipole (M1), electric quadrupole (E2) and magnetic quadrupole (M2) transitions among the 253 levels, although calculations have been performed for a much larger number of levels. Comparisons are made with existing available results and the accuracy of the data is assessed. Additionally, lifetimes for all 253 levels are listed, although comparisons with other theoretical results are limited to only 88 levels. Our energy levels are estimated to be accurate to better than 1% (within 0.03 Ryd), whereas results for other parameters are probably accurate to better than 20%. A reassessment of the energy level data on the National Institute of Standards and Technology website for Ti VI is suggested.

  6. Geothermal Program Review VI: proceedings. Beyond goals and objectives

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    Program Review VI was comprised of six sessions, including an opening session, four technical sessions that addressed each of the major DOE research areas, and a session on special issues. The technical sessions were on Hydrothermal, Hot Dry Rock, Geopressured and Magma resources. Presenters in the technical sessions discussed their R and D activities within the context of specific GTD Programmatic Objectives for that technology, their progress toward achieving those objectives, and the value of those achievements to industry. The ''Special Issues'' presentations addressed several topics such as the interactions between government and industry on geothermal energy R and D; the origin and basis for the programmatic objectives analytical computer model; and international marketing opportunities for US geothermal equipment and services. The unique aspect of Program Review VI was that it was held in conjunction with the National Geothermal Association's Industry Round Table on Federal R and D. The Round Table provided a forum for open and lively discussions between industry and government researchers and gave industry an opportunity to convey their needs and perspectives on DOE's research programs. These discussions also provided valuable information to DOE regarding industry's priorities and directions.

  7. Biosorption of Cr (VI) from aqueous solution by Rhizopus nigricans.

    Science.gov (United States)

    S Bai, R; Abraham, T E

    2001-08-01

    The study was aimed to quantify the Cr sorption ability of powdered biomass of Rhizopus nigricans at the best operating conditions. The influence of solution pH, agitation, Cr (VI) concentration, biomass dosage, contact time, biomass particle size and temperature were studied. The optimum pH for biosorption of Cr (VI) was found to be 2.0. Higher adsorption percentage was noted at lower initial concentrations of Cr ions, while the adsorption capacity of the biomass increased with increasing concentration of ions. Optimum biomass dosage was observed as 0.5% (w/v). More than 75% of the ions were removed within 30 min of contact and maximum removal was obtained after 8 h. Biomass particles of smaller size (90 microm) gave maximum adsorption (99.2%) at 100 mg/l concentration. The adsorption capacity increased with increase in temperature and agitation speed and the optimum were determined as 45 degrees C at 120 rpm. Freundlich and Langmuir isotherms were used to evaluate the data and the regression constants were derived. The adsorption rate constant values (Kad) were calculated for different initial concentration of Cr ions and the sorption was found to be higher at lower concentration (100 mg/l) of metal ion.

  8. Morphological heterogeneity of layer VI neurons in mouse barrel cortex.

    Science.gov (United States)

    Chen, Chia-Chien; Abrams, Svetlana; Pinhas, Alex; Brumberg, Joshua C

    2009-02-20

    Understanding the basic neuronal building blocks of the neocortex is a necessary first step toward comprehending the composition of cortical circuits. Neocortical layer VI is the most morphologically diverse layer and plays a pivotal role in gating information to the cortex via its feedback connection to the thalamus and other ipsilateral and callosal corticocortical connections. The heterogeneity of function within this layer is presumably linked to its varied morphological composition. However, so far, very few studies have attempted to define cell classes in this layer using unbiased quantitative methodologies. Utilizing the Golgi staining technique along with the Neurolucida software, we recontructed 222 cortical neurons from layer VI of mouse barrel cortex. Morphological analyses were performed by quantifying somatic and dendritic parameters, and, by using principal component and cluster analyses, we quantitatively categorized neurons into six distinct morphological groups. Additional systematic replication on a separate population of neurons yielded similar results, demonstrating the consistency and reliability of our categorization methodology. Subsequent post hoc analyses of dendritic parameters supported our neuronal classification scheme. Characterizing neuronal elements with unbiased quantitative techniques provides a framework for better understanding structure-function relationships within neocortical circuits in general.

  9. Learning/work: Turning work and lifelong learning inside out

    Science.gov (United States)

    Walters, Shirley; Cooper, Linda

    2011-08-01

    CONFINTEA VI took place against the background of an uneven and contradictory social and economic impact of globalisation. This impact registered globally and locally, in both the political North and South, drawing new lines of inequality between "core" and "periphery", between insiders and outsiders of contemporary society. Financial turmoil in the world has exacerbated levels of poverty and insecurity. The question is how work-related education and conceptions of learning might promote greater inclusion and security for those whose livelihoods are most severely affected by globalisation. The Belém Framework for Action implicitly recognises that lifelong learning and work cannot be discussed outside broader socio-economic and political contexts. The authors of this article draw substantially on research from around the world and argue for the re-insertion of "politics and power" into both the theory and practice of "lifelong learning" and "work".

  10. Characterization of jellyfish turning using 3D-PTV

    Science.gov (United States)

    Xu, Nicole; Dabiri, John

    2017-11-01

    Aurelia aurita are oblate, radially symmetric jellyfish that consist of a gelatinous bell and subumbrellar muscle ring, which contracts to provide motive force. Swimming is typically modeled as a purely vertical motion; however, asymmetric activations of swim pacemakers (sensory organs that innervate the muscle at eight locations around the bell margin) result in turning and more complicated swim behaviors. More recent studies have examined flow fields around turning jellyfish, but the input/output relationship between locomotive controls and swim trajectories is unclear. To address this, bell kinematics for both straight swimming and turning are obtained using 3D particle tracking velocimetry (3D-PTV) by injecting biocompatible elastomer tags into the bell, illuminating the tank with ultraviolet light, and tracking the resulting fluorescent particles in a multi-camera setup. By understanding these kinematics in both natural and externally controlled free-swimming animals, we can connect neuromuscular control mechanisms to existing flow measurements of jellyfish turning for applications in designing more energy efficient biohybrid robots and underwater vehicles. NSF GRFP.

  11. Turning shopping habits of young consumers into green

    NARCIS (Netherlands)

    Bialkova, Svetlana; van 't Erve, Sanne; van Hoof, Joris Jasper; Pruyn, Adriaan T.H.; Bigné, Enrique

    2014-01-01

    Consumers have strong shopping habits, and although being aware of sustainable issues, they hardly do green shopping. Therefore, a challenging question is: how to break the old shopping habits and turn those into green? The current study addresses this question looking at barriers and potential

  12. Optimization of turning process parameters by using grey-Taguchi

    African Journals Online (AJOL)

    DR OKE

    By applying Taguchi method the quality of manufactured goods, and engineering designs are developed by studying variations. In this work, an attempt has been made to solve the correlated multiple criteria optimization problem of turning process by considering three different process parameters viz. cutting-speed, feed ...

  13. Turn me on 100 easy ways to use solar energy

    CERN Document Server

    Kodis, Michelle

    2009-01-01

    HERE COMES THE SUN! With page after page of creative and innovative ideas for using this limitless form of energy, as well as thoughtfully compiled lists of useful resources, Turn Me On is an introductory guide to understanding the exciting advances in a progressing technology that harnesses the boundless power of the sun to bring us clean, renewable energy.

  14. On Kinesic Triadic Relations in Turn-Taking

    Science.gov (United States)

    Pike, Kenneth L.

    1975-01-01

    This article discusses three characteristics useful in defining the relations between speakers in the turn-taking aspects of conversation: the derivational history of personal relationships, stop-action pseudo-history versus dynamic compacted posing, and the criss-crossing of verbal versus kinetic axes. (Available from Semiotica, Co-Libri, P.O.…

  15. Thresholds, tipping and turning points for sustainability under climate change

    NARCIS (Netherlands)

    Werners, S.; Pfenninger, S.; van Slobbe, E.; Haasnoot, Marjolijn; Kwakkel, J.; Swart, R.J.

    2014-01-01

    We review four bodies of literature that suggest that thresholds, tipping and turning points are important focal points for sustainability under climate change that can help bridge the science–policy interface. For decision-makers a critical threshold is reached, the moment that climate change

  16. Optimization of turning process parameters by using grey-Taguchi ...

    African Journals Online (AJOL)

    The main objective of this study is to improve toughness and hardness of engineering material by changing the machining parameters of turning process. By applying Taguchi method the quality of manufactured goods, and engineering designs are developed by studying variations. In this work, an attempt has been made to ...

  17. Turn vs. Shape: Teachers Cope with Incompatible Perspectives on Angle

    Science.gov (United States)

    Kontorovich, Igor'; Zazkis, Rina

    2016-01-01

    This study is concerned with tensions between the two different perspectives on the concept of angle: angle as a static shape and angle as a dynamic turn. The goal of the study is to explore how teachers cope with these tensions. We analyze scripts of 16 in-service secondary mathematics teachers, which feature a dialogue between a teacher and…

  18. L&D Manual Turn Lane Storage Validation/Update

    Science.gov (United States)

    2012-08-01

    Queuing occurs at intersections mostly due to overflow or inadequacy of turn bays. The ODOT L&D : Manual Volume 1 has storage requirements for both signalized and unsignalized intersections. Figures : 401-9E and 401-10E of the L&D Manual provide the ...

  19. Turning Points of the Spherical Pendulum and the Golden Ratio

    Science.gov (United States)

    Essen, Hanno; Apazidis, Nicholas

    2009-01-01

    We study the turning point problem of a spherical pendulum. The special cases of the simple pendulum and the conical pendulum are noted. For simple initial conditions the solution to this problem involves the golden ratio, also called the golden section, or the golden number. This number often appears in mathematics where you least expect it. To…

  20. Social and Emotional Turn Taking for Embodied Conversational Agents

    NARCIS (Netherlands)

    Bruijnes, Merijn

    2012-01-01

    In this doctoral consortium paper I describe the theme of my research, the model-based generation of consistent emotional turn taking behavior in virtual human conversations and the evaluation of this behavior. My goal is to investigate and generate convincing social behavior in embodied