WorldWideScience

Sample records for vet rad ultrasound

  1. Predictive value of PI-RADS classification in MRI-directed transrectal ultrasound guided prostate biopsy.

    Science.gov (United States)

    NiMhurchu, E; O'Kelly, F; Murphy, I G; Lavelle, L P; Collins, C D; Lennon, G; Galvin, D; Mulvin, D; Quinlan, D; McMahon, C J

    2016-04-01

    To correlate the results of transrectal ultrasound (TRUS)-guided targeted prostate biopsies (performed in the setting of at least one previous negative biopsy) with the Prostate Imaging Reporting and Data System (PI-RADS). Fifty-two patients (mean age 64 years, range 52-76 years), with previous negative prostate biopsy underwent magnetic resonance imaging (MRI)-directed TRUS-guided targeted and sectoral biopsy. A retrospective review of MRI examinations was carried out, blinded to biopsy results. PI-RADS scores (T2, diffusion-weighted imaging [DWI] and overall) were assigned on a per lesion basis, and localised to sextants. The scores were correlated with biopsy results, and the positive predictive values (PPV) of PIRADS scores for positive biopsies were calculated. Overall, biopsies were positive in 23/52 (44.2%) patients. Eighty-one areas were targeted in 52 patients. On a per lesion basis, there was significant correlation between positive targeted biopsy and both T2 and overall PI-RADS score (pPI-RADS scores of 3, 4, and 5 were 10.6%, 44%, and 100%, respectively. The PPV of T2 PI-RADS scores of 3, 4, and 5 were 19.6%, 60%, and 100%, respectively. The PPV of DWI PI-RADS scores of 3, 4, and 5 were 50%, 27.3%, and 33%, respectively. When transitional tumours were excluded, the PPV of DWI PI-RADS 3, 4, and 5 were 40%, 43%, and 78%. The PIRADS score provides an effective framework for determining the likelihood of prostate cancer on MRI. The DWI PI-RADS score correlates well with the presence of peripheral zone tumour on targeted biopsy, but not with transitional zone tumours. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  2. Diagnostic value of breast ultrasound in mammography BI-RADS 0 and clinically indeterminate or suspicious of malignancy breast lesions

    Directory of Open Access Journals (Sweden)

    Dobrosavljević Aleksandar

    2016-01-01

    Full Text Available Background/Aim. Not only that ultrasound makes the difference between cystic and solid changes in breast tissue, as it was the case at the beginning of its use, but it also makes the differential diagnosis in terms of benign-malignant. The aim of this study was to assess the role of sonography in the diagnosis of palpable breast masses according to the American College of Radiology Ultrasonographic Breast Imaging Reporting and Data System (BI-RADS and to correlate the BI-RADS 4 and BI-RADS 5 category with pathohistological findings. Methods. A retrospective study was conducted with the breast sonograms of 30 women presented with palpable breast masses found to be mammography category BI-RADS 0 and ultrasonographic BI-RADS categories 4 and 5. The sonographic categories were correlated with pathohistological findings. Results. Surgical biopsy in 30 masses revealed: malignancy (56.7%, fibroadenoma (26.7%, fibrocystic dysplasia with/without atypia (10%, lipoma (3.3% and intramammary lymph node (3.3%. Correlation between BI-RADS categories and pathohistological findings was found (p < 0.05. All BI-RADS 5 masses were malignant, while in BI-RADS 4A category fibroadenomas dominated. A total of 53.8% of all benign lesions were found in women 49 years of age or younger as compared with 35.3% of all malignancies in this group (p < 0.05. Conclusion. Ultrasonography BI-RADS improved classification of breast masses. The ultrasound BI-RADS 4 (A, B, C and BI-RADS 5 lesions should be worked-up with biopsy.

  3. A computer-aided diagnosis system for breast ultrasound based on weighted BI-RADS classes.

    Science.gov (United States)

    Rodríguez-Cristerna, Arturo; Gómez-Flores, Wilfrido; de Albuquerque Pereira, Wagner Coelho

    2018-01-01

    Conventional computer-aided diagnosis (CAD) systems for breast ultrasound (BUS) are trained to classify pathological classes, that is, benign and malignant. However, from a clinical perspective, this kind of classification does not agree totally with radiologists' diagnoses. Usually, the tumors are assessed by using a BI-RADS (Breast Imaging-Reporting and Data System) category and, accordingly, a recommendation is emitted: annual study for category 2 (benign), six-month follow-up study for category 3 (probably benign), and biopsy for categories 4 and 5 (suspicious of malignancy). Hence, in this paper, a CAD system based on BI-RADS categories weighted by pathological information is presented. The goal is to increase the classification performance by reducing the common class imbalance found in pathological classes as well as to provide outcomes quite similar to radiologists' recommendations. The BUS dataset considers 781 benign lesions and 347 malignant tumors proven by biopsy. Moreover, every lesion is associated to one BI-RADS category in the set {2, 3, 4, 5}. Thus, the dataset is split into three weighted classes: benign, BI-RADS 2 in benign lesions; probably benign, BI-RADS 3 and 4 in benign lesions; and malignant, BI-RADS 4 and 5 in malignant lesions. Thereafter, a random forest (RF) classifier, denoted by RF w , is trained to predict the weighted BI-RADS classes. In addition, for comparison purposes, a RF classifier is trained to predict pathological classes, denoted as RF p . The ability of the classifiers to predict the pathological classes is measured by the area under the ROC curve (AUC), sensitivity (SEN), and specificity (SPE). The RF w classifier obtained AUC=0.872,SEN=0.826, and SPE=0.919, whereas the RF p classifier reached AUC=0.868,SEN=0.808, and SPE=0.929. According to a one-way analysis of variance test, the RF w classifier statistically outperforms (p < 0.001) the RF p classifier in terms of the AUC and SEN. Moreover, the

  4. Frequency and number of ultrasound lung rockets (B-lines) using a regionally based lung ultrasound examination named vet BLUE (veterinary bedside lung ultrasound exam) in dogs with radiographically normal lung findings.

    Science.gov (United States)

    Lisciandro, Gregory R; Fosgate, Geoffrey T; Fulton, Robert M

    2014-01-01

    Lung ultrasound is superior to lung auscultation and supine chest radiography for many respiratory conditions in human patients. Ultrasound diagnoses are based on easily learned patterns of sonographic findings and artifacts in standardized images. By applying the wet lung (ultrasound lung rockets or B-lines, representing interstitial edema) versus dry lung (A-lines with a glide sign) concept many respiratory conditions can be diagnosed or excluded. The ultrasound probe can be used as a visual stethoscope for the evaluation of human lungs because dry artifacts (A-lines with a glide sign) predominate over wet artifacts (ultrasound lung rockets or B-lines). However, the frequency and number of wet lung ultrasound artifacts in dogs with radiographically normal lungs is unknown. Thus, the primary objective was to determine the baseline frequency and number of ultrasound lung rockets in dogs without clinical signs of respiratory disease and with radiographically normal lung findings using an 8-view novel regionally based lung ultrasound examination called Vet BLUE. Frequency of ultrasound lung rockets were statistically compared based on signalment, body condition score, investigator, and reasons for radiography. Ten left-sided heart failure dogs were similarly enrolled. Overall frequency of ultrasound lung rockets was 11% (95% confidence interval, 6-19%) in dogs without respiratory disease versus 100% (95% confidence interval, 74-100%) in those with left-sided heart failure. The low frequency and number of ultrasound lung rockets observed in dogs without respiratory disease and with radiographically normal lungs suggests that Vet BLUE will be clinically useful for the identification of canine respiratory conditions. © 2014 American College of Veterinary Radiology.

  5. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification

    National Research Council Canada - National Science Library

    Evans, A; Whelehan, P; Thomson, K; Brauer, K; Jordan, L; Purdie, C; McLean, D; Baker, L; Vinnicombe, S; Thompson, A

    2012-01-01

    The aim of this study was to assess the performance of shear wave elastography combined with BI-RADS classification of greyscale ultrasound images for benign/malignant differentiation in a large group of patients...

  6. Usefulness of combined BI-RADS analysis and Nakagami statistics of ultrasound echoes in the diagnosis of breast lesions.

    Science.gov (United States)

    Dobruch-Sobczak, K; Piotrzkowska-Wróblewska, H; Roszkowska-Purska, K; Nowicki, A; Jakubowski, W

    2017-04-01

    To develop a method combining the statistics of the ultrasound backscatter and the Breast Imaging-Reporting and Data System (BI-RADS) classification to enhance the differentiation of breast tumours. The Nakagami shape parameter m was used to characterise the scatter properties of breast tumours. Raw data from the radiofrequency (RF) echo-signal and B-mode images from 107 (32 malignant and 75 benign) lesions and their surrounding tissue were recorded. Three different characteristic values of the shape parameters of m (maximum [mLmax], minimum [mLmin] and average [mLavg]) and differences between m parameters (Δmmax, Δmmin, Δmavg) of the lesions and their surrounding tissues were assessed. A lesion with a BI-RADS score of 3 was considered benign, while a lesion with a score of 4 was considered malignant (a cut-off of BI-RADS 3/4 was set for all patients). The area under the receiver operating characteristic (ROC) curve (AUC) was equal to 0.966 for BI-RADS, with 100% sensitivity and 54.67% specificity. All malignant lesions were diagnosed correctly, whereas 34 benign lesions were biopsied unnecessarily. In assessing the Nakagami statistics, the sum of the sensitivity and specificity was the best for mLavg (62.5% and 93.33%, respectively). Only four of 20 lesions were found over the cut-off value in BI-RADS of 4a. When comparing the differences in m parameters, Δmavg had the highest sensitivity of 90% (only three of 32 lesions were false negative). These three lesions were classified as BI-RADS category 4c. The combined use of B-mode and mLmin parameter improve the AUC up to 0.978 (p=0.088), compared to BI-RADS alone. The combination of the parametric imaging and the BI-RADS assessment does not significantly improve the differentiation of breast lesions, but it has the potential to better identify the group of patients with mainly benign lesions that have a low level of suspicion for malignancy with a BI-RADS score of 4a. Copyright © 2016 The Royal College of

  7. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification.

    Science.gov (United States)

    Evans, A; Whelehan, P; Thomson, K; Brauer, K; Jordan, L; Purdie, C; McLean, D; Baker, L; Vinnicombe, S; Thompson, A

    2012-07-10

    The aim of this study was to assess the performance of shear wave elastography combined with BI-RADS classification of greyscale ultrasound images for benign/malignant differentiation in a large group of patients. One hundred and seventy-five consecutive patients with solid breast masses on routine ultrasonography undergoing percutaneous biopsy had the greyscale findings classified according to the American College of Radiology BI-RADS. The mean elasticity values from four shear wave images were obtained. For mean elasticity vs greyscale BI-RADS, the performance results against histology were sensitivity: 95% vs 95%, specificity: 77% vs 69%, Positive Predictive Value (PPV): 88% vs 84%, Negative Predictive Value (NPV): 90% vs 91%, and accuracy: 89% vs 86% (all P>0.05). The results for the combination (positive result from either modality counted as malignant) were sensitivity 100%, specificity 61%, PPV 82%, NPV 100%, and accuracy 86%. The combination of BI-RADS greyscale and shear wave elastography yielded superior sensitivity to BI-RADS alone (P=0.03) or shear wave alone (P=0.03). The NPV was superior in combination compared with either alone (BI-RADS P=0.01 and shear wave P=0.02). Together, BI-RADS assessment of greyscale ultrasound images and shear wave ultrasound elastography are extremely sensitive for detection of malignancy.

  8. Computer-Aided Diagnosis for Breast Ultrasound Using Computerized BI-RADS Features and Machine Learning Methods.

    Science.gov (United States)

    Shan, Juan; Alam, S Kaisar; Garra, Brian; Zhang, Yingtao; Ahmed, Tahira

    2016-04-01

    This work identifies effective computable features from the Breast Imaging Reporting and Data System (BI-RADS), to develop a computer-aided diagnosis (CAD) system for breast ultrasound. Computerized features corresponding to ultrasound BI-RADs categories were designed and tested using a database of 283 pathology-proven benign and malignant lesions. Features were selected based on classification performance using a "bottom-up" approach for different machine learning methods, including decision tree, artificial neural network, random forest and support vector machine. Using 10-fold cross-validation on the database of 283 cases, the highest area under the receiver operating characteristic (ROC) curve (AUC) was 0.84 from a support vector machine with 77.7% overall accuracy; the highest overall accuracy, 78.5%, was from a random forest with the AUC 0.83. Lesion margin and orientation were optimum features common to all of the different machine learning methods. These features can be used in CAD systems to help distinguish benign from worrisome lesions. Copyright © 2016 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

  9. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification

    OpenAIRE

    Evans, A; Whelehan, P; Thomson, K; Brauer, K; Jordan, L; Purdie, C; McLean, D; Baker, L; Vinnicombe, S; Thompson, A.

    2012-01-01

    Background: The aim of this study was to assess the performance of shear wave elastography combined with BI-RADS classification of greyscale ultrasound images for benign/malignant differentiation in a large group of patients. Methods: One hundred and seventy-five consecutive patients with solid breast masses on routine ultrasonography undergoing percutaneous biopsy had the greyscale findings classified according to the American College of Radiology BI-RADS. The mean elasticity values from fou...

  10. Likelihood of malignancy in thyroid nodules according to a proposed Thyroid Imaging Reporting and Data System (TI-RADS) classification merging suspicious and benign ultrasound features.

    Science.gov (United States)

    Delfim, Ricardo Luiz Costantin; Veiga, Leticia Carrasco Garcez da; Vidal, Ana Paula Aguiar; Lopes, Flávia Paiva Proença Lobo; Vaisman, Mário; Teixeira, Patrícia de Fatima Dos Santos

    2017-01-01

    The aim of this study was to describe the ultrasound features of benign and malignant thyroid nodules and evaluate the likelihood of malignancy associated with each feature according to the Bethesda System for Reporting Thyroid Cytopathology and histopathology. With this analysis, we propose a new TI-RADS classification system. The likelihood of malignancy from ultrasound features were assessed in 1413 thyroid nodules according to the Bethesda System for Reporting Thyroid Cytopathology and histopathological findings. A score was established by attributing different weights to each ultrasound feature evaluated. Features positively associated with malignancy in bivariate analysis received a score weight of +1. We attributed a weight of +2 to features which were independently associated with malignancy in a multivariate analysis and +3 for those associated with the highest odds ratio for malignancy (> 10.0). Hence, hypoechogenicity (graded as mild, moderate or marked, according to a comparison with the overlying strap muscle), microcalcification and irregular/microlobulated margin received the highest weights in our scoring system. Features that were negatively associated with malignancy received weights of -2 or -1. In the proposed system a cutoff score of 2 (sensitivity 97.4% and specificity 51.6%) was adopted as a transition between probably benign (TI-RADS 3) and TI-RADS 4a nodules. Overall, the frequency of malignancy in thyroid nodules according to the categories was 1.0% for TI-RADS 3, 7.8% for TI-RADS 4a, 35.3% for TI-RADS 4b, and 84.7% for TI-RADS 5. A newly proposed TI-RADS classification adequately assessed the likelihood of malignancy in thyroid nodules.

  11. Performance of hand-held whole-breast ultrasound based on BI-RADS in women with mammographically negative dense breast

    Energy Technology Data Exchange (ETDEWEB)

    Youk, Ji Hyun; Kim, Eun-Kyung; Kim, Min Jung; Kwak, Jin Young; Son, Eun Ju [Yonsei University, College of Medicine, Department of Radiology, Research Institute of Radiological Science, Seoul (Korea, Republic of)

    2011-04-15

    To assess the performance of breast ultrasound based on BI-RADS final assessment categories in women with mammographically negative dense breast. Of 3,820 cases with mammographically negative dense breast and subsequent hand-held bilateral whole-breast ultrasound, a total of 1,507 cases in 1,046 women who had biopsy or at least 2-year follow-up ultrasound constituted the basis of this retrospective study. Cancer rate of each sonographic BI-RADS category was determined and medical audit was performed separately in screening-general, screening-treated, and diagnostic group. A total of 43 cases (2.9%) were confirmed as malignancy. Cancer rate among BI-RADS categories was significantly different (p < 0.0001). Among three groups, the cancer rate was significantly different (p < 0.0001) and the highest in diagnostic group (15.8%, 22 of 139). Abnormal interpretation rate, PPV of biopsy performed, cancer detection rate, and rate of early stage cancer, and the size of invasive cancer were significantly different among three groups and the highest in diagnostic group. Regarding cancer characteristics, the proportion of advanced cancer was the highest in diagnostic group. Breast ultrasound based on BI-RADS as an adjunctive to negative mammography can be useful for predicting malignancy in women with dense breast. (orig.)

  12. VET again

    DEFF Research Database (Denmark)

    Duch, Henriette; Andreasen, Karen Egedal

    2017-01-01

    newly enrolled students at a vocational college. This paper is based on empirical data from a qualitative study. It examines the learning trajectories of vocational teachers who choose to return to vocational colleges as VET teachers. Based on the analyses of two cases, we discuss the consequences...

  13. Accuracy of CESM versus conventional mammography and ultrasound in evaluation of BI-RADS 3 and 4 breast lesions with pathological correlation

    Directory of Open Access Journals (Sweden)

    Maha Helal

    2017-09-01

    Full Text Available Aim: Assess accuracy of contrast enhanced spectral mammography (CESM versus conventional mammography and ultrasound in evaluation of BI-RADS 3 and 4 breast lesions with pathological correlation. Patients and methods: Thirty female patients with 35 breast lesions diagnosed by conventional imaging as BI-RADS 3 and 4, presented to Women’s Imaging Unit of Radiology Department between January and December 2015, age ranged from 23 to 70 years. All patients underwent conventional mammography and ultrasound then CESM. Results: Patients divided into two groups, benign and malignant lesions group according to histological analysis. Mammography results that malignant lesions detected in 18/35 (51.4% while benign lesions 17/35 (48.6%. Ultrasound revealed 27/35 (77.1% lesions were malignant and 8/35 (22.9% lesions benign. But CESM, revealed 25/35 (71.4% lesions were malignant & 10/35 (28.6% lesions benign. Among 7 patients with multifocal/ multi-centric histologically proven malignant lesions, all detected by CESM 7/7 cases (100% versus 2/7 cases (28.6% and 6/7 cases (85.7% detected by mammography and ultrasound respectively. Based on, CESM had 95.2% sensitivity and 82.9% diagnostic accuracy. Conclusion: CESM has better diagnostic accuracy than mammography alone and mammography plus ultrasound. CESM has 82.9% diagnostic accuracy in comparison to 51.4% for mammography and 77.1% for ultrasound. Keywords: Breast lesions, CESM, BI-RADS lexicon

  14. Inter- and Intra-Observer Agreement in Ultrasound BI-RADS Classification and Real-Time Elastography Tsukuba Score Assessment of Breast Lesions.

    Science.gov (United States)

    Schwab, Fabienne; Redling, Katharina; Siebert, Matthias; Schötzau, Andy; Schoenenberger, Cora-Ann; Zanetti-Dällenbach, Rosanna

    2016-11-01

    Our aim was to prospectively evaluate inter- and intra-observer agreement between Breast Imaging Reporting and Data System (BI-RADS) classifications and Tsukuba elasticity scores (TSs) of breast lesions. The study included 164 breast lesions (63 malignant, 101 benign). The BI-RADS classification and TS of each breast lesion was assessed by the examiner and twice by three reviewers at an interval of 2 months. Weighted κ values for inter-observer agreement ranged from moderate to substantial for BI-RADS classification (κ = 0.585-0.738) and was substantial for TS (κ = 0.608-0.779). Intra-observer agreement was almost perfect for ultrasound (US) BI-RADS (κ = 0.847-0.872) and TS (κ = 0.879-0.914). Overall, individual reviewers are highly self-consistent (almost perfect intra-observer agreement) with respect to BI-RADS classification and TS, whereas inter-observer agreement was moderate to substantial. Comprehensive training is essential for achieving high agreement and minimizing the impact of subjectivity. Our results indicate that breast US and real-time elastography can achieve high diagnostic performance. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  15. Validation of the fifth edition BI-RADS ultrasound lexicon with comparison of fourth and fifth edition diagnostic performance using video clips

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Jung Hyun; Kim, Min Jung; Lee, Hye Sun [Yonsei University College of Medicine, Seoul (Korea, Republic of); Kim, Sung Hun [Dept. of Radiology, Seoul St. Mary' s Hospital, The Catholic University of Korea, Seoul(Korea, Republic of); Youk, Ji Hyun [Dept. of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of); Jeong, Sun Hye [Dept. of Radiology, Soonchunhyang University Bucheon Hospital, Bucheon (Korea, Republic of); Kim, You Me [Dept. of Radiology, Dankook University Hospital, Dankook University College of Medicine, Cheonan (Korea, Republic of)

    2016-08-15

    The aim of this study was to evaluate the positive predictive value (PPV) and the diagnostic performance of the ultrasonographic descriptors in the fifth edition of BI-RADS, comparing with the fourth edition using video clips. From September 2013 to July 2014, 80 breast masses in 74 women (mean age, 47.5±10.7 years) from five institutions of the Korean Society of Breast Imaging were included. Two radiologists individually reviewed the static and video images and analyzed the images according to the fourth and fifth edition of BI-RADS. The PPV of each descriptor was calculated and diagnostic performances between the fourth and fifth editions were compared. Of the 80 breast masses, 51 (63.8%) were benign and 29 (36.2%) were malignant. Suspicious ultrasonographic features such as irregular shape, non-parallel orientation, angular or spiculated margins, and combined posterior features showed higher PPV in both editions (all P<0.05). No significant differences were found in the diagnostic performances between the two editions (all P>0.05). The area under the receiver operating characteristics curve was higher in the fourth edition (0.708 to 0.690), without significance (P=0.416). The fifth edition of the BI-RADS ultrasound lexicon showed comparable performance to the fourth edition and can be useful in the differential diagnosis of breast masses using ultrasonography.

  16. Fifty years a vet.

    Science.gov (United States)

    Winter, Agnes

    2015-07-11

    Agnes Winter wanted to go to Bristol vet school to become a cattle vet, but ended up studying at Liverpool and ultimately became a sheep vet. Here, she discusses the choices she made based on the opportunities available. British Veterinary Association.

  17. Predictive values of Bi-Rads categories 3, 4 and 5 in non-palpable breast masses evaluated by mammography, ultrasound and magnetic resonance imaging; Valores preditivos das categorias 3, 4 e 5 do sistema Bi-Rads em lesoes mamarias nodulares nao-palpaveis avaliadas por mamografia, ultra-sonografia e ressonancia magnetica

    Energy Technology Data Exchange (ETDEWEB)

    Roveda Junior, Decio; Fleury, Eduardo de Castro Faria [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Faculdade de Ciencias Medicas. Servico de Diagnostico por Imagem]. E-mail: decio.jr@uol.com.br; Piato, Sebastiao [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Clinica Ginecologica; Oliveira, Vilmar Marques de [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Ginecologia Geral; Rinaldi, Jose Francisco [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Clinica de Mastologia; Ferreira, Carlos Alberto Pecci [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Faculdade de Ciencias Medicas. Dept. de Clinica Medica. Servico de Imagenologia Mamaria

    2007-03-15

    Objective: To evaluate the predictive value of BI-RADS{sup TM} categories 3, 4 and 5 in non-palpable breast masses assessed by mammography, ultrasound and magnetic resonance imaging. Materials And Methods: Twenty-nine patients with BI-RADS categories 3, 4 and 5 non-palpable breast masses identified by mammograms were submitted to complementary ultrasound and magnetic resonance imaging studies, besides excisional biopsy. In total, 30 biopsies were performed. The lesions as well as their respective BI-RADS classification into 3, 4 and 5 were correlated with the histopathological results. The predictive values calculation was made by means of specific mathematical equations. Results: Negative predictive values for category 3 were: mammography, 69.23%; ultrasound, 70.58%; and magnetic resonance imaging, 100%. Positive predictive values for category 4 were: mammography, 63.63%; ultrasound, 50%; and magnetic resonance imaging, 30.76%. For category 5, positive predictive values were: mammography and ultrasound, 100%; and magnetic resonance imaging, 92.85%. Conclusion: For category 3, the negative predictive value of magnetic resonance imaging was high, and for categories 4 and 5, the positive predictive values of the three modalities were moderate. (author)

  18. Diagnostic value of breast ultrasound in mammography BI-RADS 0 and clinically indeterminate or suspicious of malignancy breast lesions

    National Research Council Canada - National Science Library

    Dobrosavljević, Aleksandar; Rakić, Snezana; Nikoli, Branka; Raznatović, Svetlana Janković; Dikić, Svetlana Dragojević; Milosević, Zorica; Jurisić, Aleksandar; Skrobić, Milica

    2016-01-01

    Not only that ultrasound makes the difference between cystic and solid changes in breast tissue, as it was the case at the beginning of its use, but it also makes the differential diagnosis in terms of benign-malignant...

  19. Spotlight on VET: Ireland

    Science.gov (United States)

    Cedefop - European Centre for the Development of Vocational Training, 2013

    2013-01-01

    This paper provides an overview of VET (vocational education and training) in Ireland. In Ireland, the main providers of VET are the national Training and Employment Authority (FAS--a non-commercial semi-State body, part of the public sector) and vocational education committees (VECs--public sector bodies at county level responsible for vocational…

  20. Pedagogical practices in VET

    DEFF Research Database (Denmark)

    Louw, Arnt Vestergaard

    2013-01-01

    This article deals with pedagogical practices on the basic carpentry VET programme in Denmark. On the basis of an anthropologically inspired study among carpentry students at two VET schools, the prime objective of analysis is to understand the various pedagogical practices from the students...

  1. Partners Vetting System (PVS)

    Data.gov (United States)

    US Agency for International Development — PVS 2.0 is a database that supports vetting of NGOs and individuals to ensure that USAID-funded assistance does not inadvertently provide support to entities or...

  2. Innovative island mobile vet.

    Science.gov (United States)

    Forster, Dan

    2016-06-11

    One of the UK's first mobile veterinary clinics was recently awarded a Queen's Award for Innovation. Mobile Vet was launched on the Isle of Wight in 2013 by Dan Forster and his wife Kirsty, a veterinary nurse. British Veterinary Association.

  3. Prostate zonal anatomy correlates with the detection of prostate cancer on multiparametric magnetic resonance imaging/ultrasound fusion-targeted biopsy in patients with a solitary PI-RADS v2-scored lesion.

    Science.gov (United States)

    Syed, Jamil S; Nguyen, Kevin A; Nawaf, Cayce B; Bhagat, Ansh M; Huber, Steffen; Levi, Angelique; Humphrey, Peter; Weinreb, Jeffrey C; Schulam, Peter G; Sprenkle, Preston C

    2017-09-01

    To evaluate the positive predictive value (PPV) of the Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) assessment method in patients with a single suspicious finding on prostate multiparametric magnetic resonance imaging (mpMRI). A total of 176 patients underwent MRI/ultrasound fusion-targeted prostate biopsy after the detection of a single suspicious finding on mpMRI. The PPV for cancer detection was determined based on PI-RADS v2 assessment score and location. Fusion biopsy detected prostate cancer in 60.2% of patients. Of these patients, 69.8% had Gleason score (GS) ≥7 prostate cancer. Targeted biopsy detected 90.5% of all GS≥7 prostate cancer. The PPV for GS≥7 detection of PI-RADS v2 category 5 (P5) and category 4 (P4) lesions was 70.2% and 37.7%, respectively. This increased to 88% and 38.5% for P5 and P4 lesions in the peripheral zone (PZ), respectively. Targeted biopsy did not miss GS≥7 disease compared with systematic biopsy in P5 lesions in the PZ and transition zone. The PPV of PI-RADS v2 for prostate cancer in patients with a single lesion on mpMRI is dependent on PI-RADS assessment category and location. The highest PPV was for a P5 lesion in the PZ. Published by Elsevier Inc.

  4. Challenges in Danish VET

    DEFF Research Database (Denmark)

    Aarkrog, Vibe

    2011-01-01

    In Denmark the 95 percent target, meaning that in 2015 95 percent of a youth cohort should complete a youth education programme, is particularly challenging for the vocational educational and training (VET) system. In the article is given a short outline of the significant characteristics...... of the Danish dual VET system as well as of the current central initiatives aimed at reaching the 95 percent target....

  5. Diagnostic efficacy of the Liver Imaging-Reporting and Data System (LI-RADS) with CT imaging in categorising small nodules (10-20 mm) detected in the cirrhotic liver at screening ultrasound.

    Science.gov (United States)

    Abd Alkhalik Basha, M; Abd El Aziz El Sammak, D; El Sammak, A A

    2017-10-01

    To estimate the diagnostic accuracy of the Liver Imaging-Reporting and Data System (LI-RADS) with computed tomography (CT) for diagnosing hepatic nodules (10-20 mm) detected in cirrhotic livers. Fifty-five patients with liver cirrhosis and a solitary nodule (10-20 mm in diameter) detected via ultrasound surveillance, underwent hepatic CT and fine-needle biopsy. All the CT images were analysed and the lesions were categorised into five categories according to the LI-RADS. Final diagnoses of the 55 nodules were as follows: 34 hepatocellular carcinomas (HCCs), one intrahepatic cholangiocarcinomas, one adrenocortical carcinoma metastasis, and 19 benign lesions. None (0%) of four LI-RADS category 1 lesions, two (22%) of nine category 2 lesions, seven (50%) of 14 category 3 lesions, two (67%) of three category 4 lesions, 22 (96%) of 23 category 5 lesions and one (50%) of two lesions classified as other malignancies was HCC. One category 5 lesion was adrenocortical carcinoma metastasis and one of two lesions categorised as other malignancies was intrahepatic cholangiocarcinoma. In patients with nodules detected at surveillance ultrasound, the best threshold for confident HCC diagnosis was more than LI-RADS category 3. The use of this threshold produced a sensitivity and specificity of 72.7% and 90%, respectively. So combining LI-RADS 4 and 5 categories for confident HCC diagnosis would improve accuracy and sensitivity with no significant impairment of specificity or positive predictive value. LIRADS with CT provides a strong validity for the diagnosis of small hepatic nodules, and is very useful to improve the accuracy of CT reports. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  6. VET again: now as a VET teacher

    DEFF Research Database (Denmark)

    Duch, Henriette; Andreasen, Karen Egedal

    2017-01-01

    In 2010, a mandatory teacher training course was introduced for new vocational college teachers in Denmark. Since then, all vocational teachers have to complete the same course, regardless of practical work experience and educational background. After completion, they apply the knowledge to a ver...... for teachers’ pedagogical practice at vocational colleges and its potential for solving various challenges that colleges face....... newly enrolled students at a vocational college. This paper is based on empirical data from a qualitative study. It examines the learning trajectories of vocational teachers who choose to return to vocational colleges as VET teachers. Based on the analyses of two cases, we discuss the consequences...

  7. Vet Centers. Final rule.

    Science.gov (United States)

    2016-03-02

    The Department of Veterans Affairs (VA) adopts as final an interim final rule that amends its medical regulation that governs Vet Center services. The National Defense Authorization Act for Fiscal Year 2013 (the 2013 Act) requires Vet Centers to provide readjustment counseling services to broader groups of veterans, members of the Armed Forces, including a member of a reserve component of the Armed Forces, and family members of such veterans and members. This final rule adopts as final the regulatory criteria to conform to the 2013 Act, to include new and revised definitions.

  8. Differentiated teaching at VET

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Duch, Henriette

    A new education program, Diploma of Vocational Pedagogy, has recently been implemented in Denmark to upskill vocational college teachers and improve didactics at VET colleges in general. Among many challenges, vocational college teachers have to adapt their pedagogy to a large number of students...

  9. Ultrasound

    Science.gov (United States)

    Ultrasound is a type of imaging. It uses high-frequency sound waves to look at organs and ... liver, and other organs. During pregnancy, doctors use ultrasound to view the fetus. Unlike x-rays, ultrasound ...

  10. ROLE OF ULTRASOUND IN EVALUATION OF BREAST DISEASES (WITH FOCUS ON BI-RADS 1-3 VS. BI-RADS 4-5: A STUDY OF 131 CASES

    Directory of Open Access Journals (Sweden)

    Pankaj Sharma

    2016-10-01

    Full Text Available BACKGROUND Ultrasound is a radiation free, readily available imaging modality that is routinely used for evaluation of breast. The patient usually are for routine checkup to nonspecific symptoms with few showing specific signs and symptoms. In this study, an attempt has been made to understand the role of ultrasound in diagnosing benign lesions with a drawback focused on early malignant lesion. Also, the differentiation of solid and cystic lesions can reduce biopsy. MATERIALS AND METHODS This study was done retrospectively evaluating 131 consecutive patients. The ultrasound study included evaluation of mainly female patients with few male cases. RESULTS Most common lesions were benign lesions. Among these benign lesions, fibroadenomas and fibrocystic disease were the commonest. However, there were no early malignant lesion seen in this study. CONCLUSION Breast ultrasound is choice of investigation in benign breast diseases. Also, such lesions can be easily followed up at primary level. However, there is a limited role in detecting early malignant lesions, which will require additional workup at a higher level especially in high-risk groups.

  11. Evaluación de la subestimación diagnóstica e incidencia en nódulos mamarios BI-RADS 3, 4 y 5 estudiadas mediante biopsia-core guiada por ecografía Evaluation of diagnostic underestimation and incidence in BI-RADS 3, 4 and 5 nodules studied by ultrasound- guided core biopsy.

    Directory of Open Access Journals (Sweden)

    María Paula Tiscornia

    2011-12-01

    Full Text Available Objetivos. Determinar retrospectivamente el índice de falsos negativos y el grado de subestimación de la punción con aguja gruesa eco-guiada de nódulos mamarios. Establecer la incidencia de las diferentes lesiones que se manifiestan como nódulos mamarios. Materiales y Métodos. Se estudiaron las punciones de nódulos mamarios desde enero del 2000 a septiembre del 2010. Las mismas fueron realizadas por un radiólogo con 10 años de experiencia y se utilizaron agujas de corte de 14-gauge y 10 cm de longitud. Para la guía ecográfica se usaron dos ecógrafos con transductores lineales de 5-12 MHz. Se punzaron lesiones de moderada y alta sospecha de malignidad (BI-RADS 4 y 5 y algunas lesiones probablemente benignas (BI-RADS 3. Se correlacionaron los hallazgos histológicos de la punción y de la cirugía para cada lesión. A los casos con resultado benigno que no fueron operados se les realizó un seguimiento clínico de entre uno y diez años. Resultados. Se realizaron 190 punciones. El índice de falsos negativos fue del 3%, la sensibilidad de 95% y la especificidad de 100% (VPP de 100% y VPN de 95%. Discusión. Hubo coincidencia entre los resultados de las punciones y la cirugía en un 94%. El índice de falsos negativos es aceptable en comparación con otros reportes donde varía entre 0 y 8%. Conclusiones. Este estudio indica que la punción con aguja de corte eco-guiada es un método válido, con alto grado de precisión y bajo índice de subestimación y falsos negativos para el diagnóstico de nódulos mamarios malignos y benignos. Esto fue comprobado mediante la escisión quirúrgica y/o el seguimiento clínico- imagenológico de las diferentes lesiones.Objectives. To retrospectively determine the false negatives rate and the extent of underestimation of ultrasound-guided core biopsy of breast nodules, and to determine the incidence of the various lesions presenting as breast nodules. Materials and Methods. We studied core biopsies

  12. MyHealtheVet Service

    Data.gov (United States)

    Department of Veterans Affairs — This service provides web services used to obtain MyHealtheVet related data. The service does not support multiple Vista sites data access. Users of this service are...

  13. Ultrasound

    Science.gov (United States)

    ... reflect off body structures. A computer receives the waves and uses them to create a picture. Unlike with an x-ray or CT scan, this test does not use ionizing radiation. The test is done in the ultrasound ...

  14. VetSuccess on Campus (VSOC)

    Data.gov (United States)

    Department of Veterans Affairs — The VSOC program provides a VA Vocational Rehabilitation Counselor (VRC) to each VSOC school. These VRCs are called VetSuccess on Campus (VSOC) Counselors. A VA Vet...

  15. Vet Centers. Interim final rule.

    Science.gov (United States)

    2015-08-04

    The Department of Veterans Affairs (VA) is amending its medical regulation that governs Vet Center services. The National Defense Authorization Act for Fiscal Year 2013 (the 2013 Act) requires Vet Centers to provide readjustment counseling services to broader groups of veterans, members of the Armed Forces, including a member of a reserve component of the Armed Forces, and family members of such veterans and members. This interim final rule amends regulatory criteria to conform to the 2013 Act, to include new and revised definitions.

  16. Choosing VET: Aspirations, Intentions and Choice

    Science.gov (United States)

    Hargreaves, Jo; Osborne, Kristen

    2017-01-01

    This summary brings together the findings from two research projects: "Choosing VET: Investigating the VET Aspirations of School Students" and "In Their Words: Student Choice in Training Markets--Victorian Examples." The research investigated school students' post-school aspirations for vocational education and training (VET),…

  17. Hybrid Learning Environments in VET

    NARCIS (Netherlands)

    Aimee Hoeve; Dr. Ilya Zitter

    2014-01-01

    Vocational education and training (VET) plays a central role in preparing young people for work, developing adequate skills and responding to the labour-market needs of the economy. The transition learners are required to make from education to the workplace is a complex, and often problematic,

  18. Promoting VET teachers’ innovative behaviour

    NARCIS (Netherlands)

    Runhaar, Piety; Bednall, Timothy; Sanders, Karin; Yang, Huadong

    2016-01-01

    Changing employer demands, new technological and pedagogical insights are examples of developments which urge Vocational Education and Training (VET) institutes to continually renew and innovate their educational programmes. This, in turn, requires teachers to show innovative behaviour. Our study

  19. Scholarships for European vet students.

    Science.gov (United States)

    Egan, Jordon; Takacs, Daniella

    2017-02-25

    Every year, students from European vet schools can apply for $5000 scholarships, which aim to 'enhance the academic experience of students'. Among last year's recipients were Jordon Egan, from the Royal Veterinary College, and Daniella Takács, from the University of Veterinary Medicine in Budapest. British Veterinary Association.

  20. Who attends Vet-to-Vet? Predictors of attendance in mental health mutual support.

    Science.gov (United States)

    Resnick, Sandra G; Rosenheck, Robert A

    2010-01-01

    This study examines predictors of attendance in Vet-to-Vet, a peer education intervention for veterans co-located with a professionally-run rehabilitative day program. Participants were 218 veterans receiving services from a VA day program at time of study entry who enrolled in an outcome study of Vet-to-Vet. Using multiple regression analysis, baseline variables were examined as predictors of attendance in Vet-to-Vet over the 9-month study period. Attendance over 9 months was associated with attending Vet-to-Vet prior to study enrollment, receiving services from the day program at the one-month follow-up, lower scores on a recovery attitude scale, lower scores on activities of daily living, and greater age. Co-locating peer education or other mutual support programs with professional mental health services may increase participation, and those with more severe functional disabilities and less recovery orientation may participate more actively.

  1. Understanding Dilemmas Faced by VET Teachers and Their Implications for International Students, Teachers and VET Institutions

    Science.gov (United States)

    Nakar, Sonal

    2016-01-01

    This paper focuses on the voices and experiences of teachers, who are key stakeholders in the sustainability and future growth of vocational education and training (VET). It presents implications arising from qualitative research on the dilemmas that VET teachers face in teaching international students. In-depth interviewing with 15 VET teachers…

  2. The VET System and Industrial SMEs: The Role of Employees with VET Qualifications in Innovation Processes

    Science.gov (United States)

    Brunet Icart, Ignasi; Rodríguez-Soler, Joan

    2017-01-01

    Reforms of the vocational education and training (VET) system in Spain are committed to a closer relationship between the VET system and companies' needs. One of these needs is for a greater contribution of the VET system to innovation in companies, especially SMEs, which have limited resources to innovate. This contribution could materialise…

  3. Developing VET Applied Research: Steps towards Enhancing VET's Role in the Innovation System

    Science.gov (United States)

    Beddie, Francesca M.; Simon, Linda

    2017-01-01

    The VET sector is under pressure from the exponential increase in university places. This, on top of cutbacks to government funding over the last decade and a lack of clarity about VET's role now that it is squeezed between universities and schools, has led to a precarious position for the VET sector and the need to consider changes to traditional…

  4. VET Practitioner's Perceptions of VET Higher-Education Qualifications

    Science.gov (United States)

    Redmond, Petrea

    2017-01-01

    The quality of vocation education and training (VET) teaching in Australia has long been contested. Six Australian universities jointly conducted an online survey exploring the experiences of practitioners who were undertaking undergraduate studies in VET. This paper explores the experiences of VET practitioners as students in one regional…

  5. Calibration of the TonoVet and Tono-Pen Vet tonometers in the porcine eye.

    Science.gov (United States)

    Lewin, Andrew C; Miller, Paul E

    2017-11-01

    The pig has an increasingly important role in ocular drug delivery models, but the most accurate tonometer in this species is unknown. The purpose of this study was to evaluate the accuracy of TonoVet and Tono-Pen Vet tonometers in the ex vivo porcine eye. Four freshly enucleated normal porcine eyes were cannulated with two 25-gauge needles; one connected via tubing to a mercury manometer calibrated continuous physiologic recorder and the other connected to a reservoir of lactated Ringer's solution on an adjustable stand. Triplicate IOP readings were taken with the TonoVet and then the Tono-Pen Vet at 5, 10, 15, 20, 25, 30, 35, 40, 50, 60, 70, 80 mmHg. Linear regression showed strong linear trends for both the TonoVet (r 2 = 0.969) and Tono-Pen Vet (r 2 = 0.983). The TonoVet slightly underestimated IOP at lower pressures and slightly overestimated IOP at higher pressures (y = 1.092x - 4.0, where y = tonometer reading, x = manometer reading, and 4.0 = intercept). The Tono-Pen Vet consistently underestimated IOP (y = 0.773x - 2.1). These differences were statistically significant (P = Vet tonometers do not measure true IOP in the porcine eye; however, the TonoVet more closely approximated true IOP in the normal porcine eye than the Tono-Pen Vet and may be the tonometer of choice for this species. © 2016 American College of Veterinary Ophthalmologists.

  6. The Determinants of VET Educators' Occupational Choice

    Science.gov (United States)

    Berger, Jean-Louis; Girardet, Céline

    2015-01-01

    Purpose: Potential teacher shortage and low esteem of vocational education and training (VET) educator profession, together with the importance of attracting individuals best suited for the profession, lead to concerns about the reasons why people become VET educators as a second career. Accordingly, the purpose of this paper is to investigate the…

  7. Get involved in the Young Vet Network.

    Science.gov (United States)

    2016-07-02

    BVA's Young Vet Network (YVN) supports members from their final year at vet school to eight years after graduation. It is during this period that graduates particularly benefit from access to peer support. Here Tim Keen, BVA marketing manager, provides an update on what's happening. British Veterinary Association.

  8. Explaining the VET Applied Research Developmental Framework

    Science.gov (United States)

    Simon, Linda; Beddie, Francesca M.

    2017-01-01

    This document explains the VET Applied Research Developmental Framework, created as part of a project that explored how the vocational education and training (VET) sector could broaden its engagement in Australia's research and development (R&D) and innovation systems. Achieving this engagement will rely significantly on building the…

  9. Vet

    Science.gov (United States)

    Fischer, R. X.; Baur, W. H.

    This document is part of Subvolume F 'Zeolite-Type Crystal Structures and their Chemistry. Framework Type Codes STO to ZON' of Volume 14 'Microporous and other Framework Materials with Zeolite-Type Structures' of Landolt-Börnstein Group IV 'Physical Chemistry'.

  10. RadWorks Project

    Data.gov (United States)

    National Aeronautics and Space Administration — For the first two years of the project (FY12-13), the RadWorks project has consisted of two top-level elements. The first element involved the prototype and...

  11. RadMap

    Science.gov (United States)

    RadMap is an interactive desktop tool featuring a nationwide geographic information systems (GIS) map of long-term radiation monitoring locations across the United States with access to key information about the monitor and the area surrounding it.

  12. Challenges for Nordic VET-systems

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    2015-01-01

    The systems of vocational education and training (VET) in the Nordic Countries all face a similar challenge: to offer double qualifications. The Nordic VET-systems are expected to give access not only to skilled employment, but also to higher education. As an increasing share of young people...... is opting for higher education, VET runs a risk of becoming a dead end in the educational system. Consequently, VET is required to offer double qualifications, and even to provide these qualifications in an integrated form as hybrid qualifications (Deissinger et.al 2013). In the Nordic Countries....... This situation calls for new solutions to tackle the challenge of double qualifications. The question, which I will examine in this chapter, is how the Nordic VET-systems have handled this challenge in different ways and what these systems can learn from Switzerland, which is often highlighted as a model...

  13. Ultrasound pregnancy

    Science.gov (United States)

    ... sonogram; Ultrasound - pregnancy; IUGR - ultrasound; Intrauterine growth - ultrasound; Polyhydramnios - ultrasound; Oligohydramnios - ultrasound; Placenta previa - ultrasound; Multiple pregnancy - ...

  14. Australian Vocational Education and Training Statistics. VET in Schools, 2009

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2010

    2010-01-01

    This publication presents information on vocational education and training (VET) undertaken by school students as part of their senior secondary certificate, known as VET in Schools. The VET in Schools arrangement offers two main options: students can undertake school-based apprenticeships and traineeships; or VET subjects and courses (the latter…

  15. VET in Schools 2016. Australian Vocational Education and Training Statistics

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2017

    2017-01-01

    This publication presents information on VET in Schools, the vocational education and training (VET) undertaken by school students as part of their senior secondary certificate of education. The VET in Schools arrangement offers two main options: students can undertake school-based apprenticeships and traineeships; or they can take VET subjects…

  16. VET in Schools 2015. Australian Vocational Education and Training Statistics

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2016

    2016-01-01

    This report presents information on VET in Schools, the vocational education and training (VET) undertaken by school students as part of their senior secondary certificate. The VET in Schools arrangement offers two main options: students can undertake school-based apprenticeships and traineeships; or they can take VET subjects and courses as part…

  17. A thyroid nodule classification method based on TI-RADS

    Science.gov (United States)

    Wang, Hao; Yang, Yang; Peng, Bo; Chen, Qin

    2017-07-01

    Thyroid Imaging Reporting and Data System(TI-RADS) is a valuable tool for differentiating the benign and the malignant thyroid nodules. In clinic, doctors can determine the extent of being benign or malignant in terms of different classes by using TI-RADS. Classification represents the degree of malignancy of thyroid nodules. TI-RADS as a classification standard can be used to guide the ultrasonic doctor to examine thyroid nodules more accurately and reliably. In this paper, we aim to classify the thyroid nodules with the help of TI-RADS. To this end, four ultrasound signs, i.e., cystic and solid, echo pattern, boundary feature and calcification of thyroid nodules are extracted and converted into feature vectors. Then semi-supervised fuzzy C-means ensemble (SS-FCME) model is applied to obtain the classification results. The experimental results demonstrate that the proposed method can help doctors diagnose the thyroid nodules effectively.

  18. Young Vet Network - exciting times ahead.

    Science.gov (United States)

    2017-01-07

    Last year was a busy one for the Young Vet Network (YVN) as increased support from BVA spurred activity and growth. BVA marketing manager Tim Keen explains how BVA's support will continue in 2017. British Veterinary Association.

  19. Partner Vetting System - Gaza & West Bank

    Data.gov (United States)

    US Agency for International Development — The PVS WB system supports the vetting of NGOs, their employees, and individuals who apply for USAID contracts, grants, cooperative agreements, or other funding...

  20. VET in practice - and in politics

    DEFF Research Database (Denmark)

    Koudahl, Peter

    2016-01-01

    This draft paper addresses the issue of building the bridges between VET politics, practice and research and contributes to the ambition of making evidence based policy making possible. The examples derive from the Danish context but the principle of understanding and analyzing VET politics...... and practices will apply on other contexts both in EU countries and Non EU countries. The theoretical approach is the theory of social fields developed by Pierre Bourdieu. On major point of departure for the analysis is the fact that despite many political attempts to change the way VET systems in different...... countries functions in practice most attempts political intervention has little or no effect. In other words the basic principles on which VET is founded are more or less resistant to outside interventions (Koudahl 2006). One example is the discussion on how to provide a sufficient number of company based...

  1. Career development at London Vet Show.

    Science.gov (United States)

    2016-09-03

    Are you considering a career change? Perhaps you want help to develop within your current role? Either way, you will find a relevant session in the BVA Career Development stream at the London Vet Show in November. British Veterinary Association.

  2. Solar Training Network and Solar Ready Vets

    Energy Technology Data Exchange (ETDEWEB)

    Dalstrom, Tenley Ann

    2016-09-14

    In 2016, the White House announced the Solar Ready Vets program, funded under DOE's SunShot initiative would be administered by The Solar Foundation to connect transitioning military personnel to solar training and employment as they separate from service. This presentation is geared to informing and recruiting employer partners for the Solar Ready Vets program, and the Solar Training Network. It describes the programs, and the benefits to employers that choose to connect to the programs.

  3. Choosing VET: Investigating the VET Aspirations of School Students. NCVER Research Report

    Science.gov (United States)

    Gore, Jennifer; Ellis, Hywel; Fray, Leanne; Smith, Maxwell; Lloyd, Adam; Berrigan, Carly; Lyell, Andrew; Weaver, Natasha; Holmes, Kathryn

    2017-01-01

    This study explores the views of 6,492 New South Wales (NSW) primary and secondary school students' post-school aspirations. It explores when vocational education and training (VET) begins to feature in students' thinking about their futures, the kinds of students who think about VET, and under what conditions. The study informs how teachers,…

  4. VET Applied Research: Driving VET's Role in the Innovation System

    Science.gov (United States)

    Beddie, Francesca M.; Simon, Linda

    2017-01-01

    Innovation has become an increasingly important concept for Australian businesses in enabling them to continue to compete in an international market, but where does vocational education and training (VET) sit in this? To date, VET has been largely overlooked by the National Innovation and Science Agenda as a potential contributor in this field.…

  5. Pedagogical quality of VET teachers and management in Denmark

    DEFF Research Database (Denmark)

    Gottlieb, Susanne

    2016-01-01

    This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article...... is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from...... the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider VET teacher education, research, and This article is written from the viewpoint of a provider...

  6. Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2

    Science.gov (United States)

    Ikawa, Shukuko; Mimida, Naozumi; Shimizu, Takeshi; Toki, Seiichi; Ichikawa, Hiroaki; Shibata, Takehiko; Kurumizaka, Hitoshi

    2013-01-01

    In higher eukaryotes, RAD51 functions as an essential protein in homologous recombination and recombinational repair of DNA double strand breaks. During these processes, RAD51 catalyzes homologous pairing between single-stranded DNA and double-stranded DNA. Japonica cultivars of rice (Oryza sativa) encode two RAD51 proteins, RAD51A1 and RAD51A2, whereas only one RAD51 exists in yeast and mammals. However, the functional differences between RAD51A1 and RAD51A2 have not been elucidated, because their biochemical properties have not been characterized. In the present study, we purified RAD51A1 and RAD51A2, and found that RAD51A2 robustly promotes homologous pairing in vitro. RAD51A1 also possesses homologous-pairing activity, but it is only about 10% of the RAD51A2 activity. Both RAD51A1 and RAD51A2 bind to ssDNA and dsDNA, and their DNA binding strictly requires ATP, which modulates the polymer formation activities of RAD51A1 and RAD51A2. These findings suggest that although both RAD51A1 and RAD51A2 have the potential to catalyze homologous pairing, RAD51A2 may be the major recombinase in rice. PMID:24124491

  7. Homologous pairing activities of two rice RAD51 proteins, RAD51A1 and RAD51A2.

    Directory of Open Access Journals (Sweden)

    Yuichi Morozumi

    Full Text Available In higher eukaryotes, RAD51 functions as an essential protein in homologous recombination and recombinational repair of DNA double strand breaks. During these processes, RAD51 catalyzes homologous pairing between single-stranded DNA and double-stranded DNA. Japonica cultivars of rice (Oryza sativa encode two RAD51 proteins, RAD51A1 and RAD51A2, whereas only one RAD51 exists in yeast and mammals. However, the functional differences between RAD51A1 and RAD51A2 have not been elucidated, because their biochemical properties have not been characterized. In the present study, we purified RAD51A1 and RAD51A2, and found that RAD51A2 robustly promotes homologous pairing in vitro. RAD51A1 also possesses homologous-pairing activity, but it is only about 10% of the RAD51A2 activity. Both RAD51A1 and RAD51A2 bind to ssDNA and dsDNA, and their DNA binding strictly requires ATP, which modulates the polymer formation activities of RAD51A1 and RAD51A2. These findings suggest that although both RAD51A1 and RAD51A2 have the potential to catalyze homologous pairing, RAD51A2 may be the major recombinase in rice.

  8. The Social Stratification of the German VET System

    Science.gov (United States)

    Protsch, Paula; Solga, Heike

    2016-01-01

    Germany is widely known for its vocational education and training (VET) system and its dual apprenticeship system in particular. What is often overlooked, however, is the vertical stratification within the German VET system. This is the focus of this study. Our analysis shows that the VET system, like the German school system, is highly…

  9. Vocational Education and Training Programs (VET): An Asian Perspective

    Science.gov (United States)

    Agrawal, Tushar

    2013-01-01

    This paper makes an attempt to provide a review on challenges, outcomes and present situation in vocational education and training (VET) programs in some Asian countries. Various country-specific studies indicate that the VET system has not responded very well in the South Asian region. The VET stream is quite small. Despite there being a growing…

  10. Competence-based VET as seen by Dutch researchers

    NARCIS (Netherlands)

    Wesselink, R.; Biemans, H.J.A.; Mulder, M.; Elsen, van den E.

    2007-01-01

    The concept of competence is increasingly the basis for (re)designing VET. In competence-based VET academic disciplines are no longer starting points for curriculum development. Competence needed for working in practice, however, is. Competence-based learning is a dominant trend in VET in several

  11. See you at London Vet Show.

    Science.gov (United States)

    2016-11-05

    London Vet Show is fast approaching: it takes place from November 17 to 18 and is being held at ExCeL London for the first time. Zoe Davies, marketing manager, highlights some of what BVA is offering at the event. British Veterinary Association.

  12. Renewing VET Provision: Understanding Feedback Mechanisms between Initial VET and the Labour Market. Research Paper No 37

    Science.gov (United States)

    Cedefop - European Centre for the Development of Vocational Training, 2013

    2013-01-01

    A strong VET system is increasingly seen as essential to overcoming the current economic crisis in Europe. VET is seen as a powerful tool to assist in balancing labour market inefficiencies, increasing youth employment possibilities, and reducing skills mismatch. Its inherent flexibility and closeness to the labour market place VET in a good…

  13. Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2

    OpenAIRE

    Yuichi Morozumi; Ryohei Ino; Shukuko Ikawa; Naozumi Mimida; Takeshi Shimizu; Seiichi Toki; Hiroaki Ichikawa; Takehiko Shibata; Hitoshi Kurumizaka

    2013-01-01

    In higher eukaryotes, RAD51 functions as an essential protein in homologous recombination and recombinational repair of DNA double strand breaks. During these processes, RAD51 catalyzes homologous pairing between single-stranded DNA and double-stranded DNA. Japonica cultivars of rice (Oryza sativa) encode two RAD51 proteins, RAD51A1 and RAD51A2, whereas only one RAD51 exists in yeast and mammals. However, the functional differences between RAD51A1 and RAD51A2 have not been elucidated, because...

  14. Practical and illustrated summary of updated BI-RADS for ultrasonography

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ji Yon [Dept. of Radiology, NYU School of Medicine, NYU Cancer Institute, Breast Imaging Center, New York (United States)

    2017-01-15

    The American College of Radiology released the fifth edition of the Breast Imaging-Reporting and Data System (BI-RADS) in 2014 (copyright 2013), which includes the expanded second edition of the ultrasound BI-RADS lexicon. This review provides a practical summary of the updated lexicon, including selective illustrations with original clinical images, a discussion of overarching concepts, and examples of current clinical applications.

  15. Practical and illustrated summary of updated BI-RADS for ultrasonography

    OpenAIRE

    Jiyon Lee

    2016-01-01

    The American College of Radiology released the fifth edition of the Breast Imaging-Reporting and Data System (BI-RADS) in 2014 (copyright 2013), which includes the expanded second edition of the ultrasound BI-RADS lexicon. This review provides a practical summary of the updated lexicon, including selective illustrations with original clinical images, a discussion of overarching concepts, and examples of current clinical applications.

  16. Rad Pole Cam Development

    Energy Technology Data Exchange (ETDEWEB)

    Heckendorn, F. M.; Odell, D. M. C; Harpring, L. J.; Peterson, K. D.

    2005-10-05

    The RadPoleCam was developed to provide Department Of Energy (DOE) first responders the capability to assess the radiological and visual condition of remote or inaccessible locations. Real time gamma isotopic identification is provided to the first responder in the form of audio feedback (i.e. spoken through head phones) from a gamma detector mounted on a collapsible pole that can extend from 1 to 9 meters (6 to 29 feet). Simultaneously, selectable direct and side looking visual images are provided from the 5cm (2in) diameter, waterproof probe tip. The lightweight, self contained, ruggedized, system will provide a rapidly deployable field system for visual and radiological search and assessment of confined spaces and extended reach locations.

  17. Duplex ultrasound

    Science.gov (United States)

    Vascular ultrasound; Peripheral vascular ultrasound ... A duplex ultrasound combines: Traditional ultrasound: This uses sound waves that bounce off blood vessels to create pictures. Doppler ultrasound: This ...

  18. Enhancing the role of the dairy vet.

    Science.gov (United States)

    2016-09-03

    More than 3000 veterinarians, researchers and industry representatives gathered in Dublin in July for the 29th congress of the World Association for Buiatrics. With the theme of 'Cattle health - tomorrow's thinking today', the programme for the five-day meeting was wide-ranging, exploring issues such as animal health systems, animal welfare initiatives, zoonoses, mastitis control and infectious disease control. Here, Kristy Ebanks focuses on two keynote addresses which considered the evolving role of the dairy vet. British Veterinary Association.

  19. Could ultrasonic elastography help the diagnosis of small ({<=}2 cm) breast cancer with the usage of sonographic BI-RADS classification?

    Energy Technology Data Exchange (ETDEWEB)

    Zhi, Hui, E-mail: kendy181hui@yahoo.com.cn [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Xiao, Xiao-yun, E-mail: papayaxxy@163.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Ou, Bing, E-mail: oubing77@163.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Zhong, Wen-jing, E-mail: zhongwj7111@126.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Zhao, Zi-zhuo, E-mail: solo_zzz@126.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Zhao, Xin-bao, E-mail: zxb8166@126.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Yang, Hai-yun, E-mail: haiyun1972@sohu.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China); Luo, Bao-ming, E-mail: baomingluo2005@126.com [Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiangxi Rd, Guangzhou 510120, Guangdong Province (China)

    2012-11-15

    Objectives: To evaluate the additive value of ultrasound strain elastography (USE) to BI-RADS for the differentiation of benign and malignant breast small lesions. Methods: Breast masses ({<=}2 cm) with histological diagnosis examined by ultrasonography and USE in our department from April 2004 to December 2009 were reviewed. Conventional B-mode ultrasound findings were classified according to the BI-RADS classification. USE findings were classified according to the 5-point scale. Histological diagnosis was used as the reference standard. Results: 401 (246 benign (61.3%), 155 malignant (38.7%)) from 370 consecutive patients were included in the study. Sensitivity and specificity were 90.3%, 68.3% for BI-RADS; 72.3%, 91.9% for USE. The sensitivity of BI-RADS was better than that of USE (P < 0.05), while the specificity of USE was better than that of BI-RADS (P < 0.05). A revised BI-RADS combined with USE results was proposed in this study. Sensitivity and specificity were 83.9% and 87.8% for revised BI-RADS. The diagnostic performance of revised BI-RADS was better than BI-RADS (P < 0.05). Conclusions: USE could give BI-RADS some help in the differentiation of benign and malignant breast small lesions. The addition of elastography to BI-RADS could improve the diagnostic performance in <2 cm lesions.

  20. The RadAssessor manual

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, Sharon L.

    2007-02-01

    THIS manual will describe the functions and capabilities that are available from the RadAssessor database and will demonstrate how to retrieve and view its information. You’ll learn how to start the database application, how to log in, how to use the common commands, and how to use the online help if you have a question or need extra guidance. RadAssessor can be viewed from any standard web browser. Therefore, you will not need to install any special software before using RadAssessor.

  1. Evaluating the performance of PI-RADS v2 in the non-academic setting.

    Science.gov (United States)

    Jordan, Eric J; Fiske, Charles; Zagoria, Ronald J; Westphalen, Antonio C

    2017-11-01

    To evaluate the utility of PI-RADS v2 to diagnose clinically significant prostate cancer (CS-PCa) with magnetic resonance ultrasound (MR/US) fusion-guided prostate biopsies in the non-academic setting. Retrospective analysis of men whom underwent prostate multiparametric MRI and subsequent MR/US fusion biopsies at a single non-academic center from 11/2014 to 3/2016. Prostate MRIs were performed on a 3-Tesla scanner with a surface body coil. The Prostate Imaging Reporting and Data System (PI-RADS) v2 scoring algorithm was utilized and MR/US fusion biopsies were performed in selected cases. Mixed effect logistic regression analyses and receiver-operating characteristic (ROC) curves were performed on PI-RADS v2 alone and combined with PSA density (PSAD) to predict CS-PCa. 170 patients underwent prostate MRI with 282 PI-RADS lesions. MR/US fusion diagnosed 71 CS-PCa, 33 Gleason score 3+3, and 168 negative. PI-RADS v2 score is a statistically significant predictor of CS-PCa (P PI-RADS v2 score, the odds of having CS-PCa increases by 4.2 (95% CI 2.2-8.3). The area under the ROC curve for PI-RADS v2 is 0.69 (95% CI 0.63-0.76) and for PI-RADS v2 + PSAD is 0.76 (95% CI 0.69-0.82), statistically higher than PI-RADS v2 alone (P PI-RADS 4 or 5 lesion was detected (P = 0.005). PI-RADS v2 is a strong predictor of CS-PCa in the non-academic setting and can be further strengthened when utilized with PSA density.

  2. [Interaction between checkpoint genes RAD9, RAD17, RAD24, and RAD53 involved in the determination of yeast Saccharomyces cerevisiae sensitivity to ionizing radiation].

    Science.gov (United States)

    Koltovaia, N A; Nikulushkina, Iu V; Kadyshevskaia, E Iu; Roshchina, M P; Devin, A B

    2008-08-01

    Mechanisms for genetic control of cell division cycle (checkpoint control) have been studied in most detail in yeast Saccharomyces cerevisiae. To clarify the role of checkpoint genes RAD9, RAD17, RAD24, and RAD53 in cell radioresistance, double mutants were analyzed for cell sensitivity to ionizing radiation. Double mutants carrying mutations in combination with mutation rad9Delta were shown to manifest the epistatic type of interaction. Our results suggest that checkpoint genes RAD9, RAD17, RAD24, and RAD53 belong to a single epistatic group designated RAD9 and govern the same pathway. Genes RAD9 and RAD53 have a positive effect on sensitivity to gamma-radiation, whereas RAD17 and RAD24 have a negative effect. Interactions between mutations may differ when considering their sensitivity to gamma-radiation and UV light; mutations rad9Delta and rad24Delta were shown to manifest the additive effect in the first case and epistatic effect in the second.

  3. The current state of the challenges for VET in Denmark

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    The aim of this report is to analyse the way the Danish VET system has been coping with four challenges in the last decades. First the report describes key features of the institutional architecture of the current Danish VET-system. In the next two sections priority is given to the challenges....... The report examines how the VET systems connects with the labour market and explores the patterns of transition of the students from VET to the labour market and describes indications of their mobility and employability. In the following section the report focusses on the second challenge for vocational...... the suc-cess of subsequent reforms of VET in improving the connections between VET and higher educa-tion, latest with the reform in 2013. The next challenge to be examined is that of social inclusion. This is mainly a question of raising the retention of students in the vocational programmes, where...

  4. RadFlexPro Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Our proposed multilayered, flexible, graded Z radiation shielding, RadFlexPro, provides radiation protection for astronauts in EVA for NASA's future space missions....

  5. RadMap Installation Instructions

    Science.gov (United States)

    RadMap is an interactive desktop tool featuring a nationwide geographic information systems (GIS) map of long-term radiation monitoring locations across the United States with access to key information about the monitor and the area surrounding it.

  6. Rad10-YFP focus induction in response to UV depends on RAD14 in yeast.

    Science.gov (United States)

    Mardiros, Armen; Benoun, Joseph M; Haughton, Robert; Baxter, Kelly; Kelson, Eric P; Fischhaber, Paula L

    2011-07-01

    Rad14 is a DNA damage recognition protein in yeast Nucleotide Excision Repair (NER) and believed to function early in the cascade of events. The function of Rad14 presumably precedes that of the Rad1-Rad10 endonuclease complex, which functions in a downstream step incising DNA 5' to the site of DNA damage. We investigated whether recruitment of Rad10 to UV-induced DNA damage sites in live cells is dependent on Rad14 using fluorescence microscopy. Experiments were carried out using Saccharomyces cerevisiae strains in which the gene for Rad14 was fused to Cyan Fluorescent Protein (Rad14-CFP) and that of Rad10 was fused to Yellow Fluorescent Protein (Rad10-YFP). Rad14-CFP forms nuclear localized CFP fluorescent foci in response to UV irradiation with the peak induction occurring 15min post-irradiation. In contrast, Rad10-YFP foci form in response to UV with the peak induction occurring 2h post-irradiation. Recruitment of Rad14-CFP is not dependent on the RAD10 gene but Rad10-YFP is recruited to UV-induced YFP foci in a RAD14-dependent fashion. Time-lapse experiments indicate that Rad14-CFP foci are transient, typically persisting less than 6min. Together these data support the model that yeast NER protein assembly is step-wise whereas Rad14 required to recruit Rad10 and Rad14 involvement is transient. Published by Elsevier GmbH.

  7. Walk like a vet, think like an owner.

    Science.gov (United States)

    2016-11-26

    Owners consulting the internet before venturing into a veterinary practice is a real issue in today's technological age, but how often do vets step into the owner's shoes and try to understand why they do so? On the farm, what are the motivations of the farmer, and are these being listened to by the vet? These were just some of the questions raised in a session at the BVA Congress during the London Vet Show last week. Georgina Mills reports. British Veterinary Association.

  8. What Makes a Good VET Teacher? Views of Australian VET Teachers and Students

    Science.gov (United States)

    Smith, Erica; Yasukawa, Keiko

    2017-01-01

    The quality of teaching in the vocational education and training (VET) sector in Australia has been an area of concern for much of the twenty-first century (e.g. Department of Education and Training, 2016). While much debate has taken place about ways forward, there has been little substantive progress in reforming the education and professional…

  9. Rad52 and Rad59 exhibit both overlapping and distinct functions

    DEFF Research Database (Denmark)

    Feng, Qi; Düring, Louis; Antúnez de Mayolo, Adriana

    2007-01-01

    Homologous recombination is an important pathway for the repair of DNA double-strand breaks (DSBs). In the yeast Saccharomyces cerevisiae, Rad52 is a central recombination protein, whereas its paralogue, Rad59, plays a more subtle role in homologous recombination. Both proteins can mediate...... annealing of complementary single-stranded DNA in vitro, but only Rad52 interacts with replication protein A and the Rad51 recombinase. We have studied the functional overlap between Rad52 and Rad59 in living cells using chimeras of the two proteins and site-directed mutagenesis. We find that Rad52 and Rad...

  10. VET Manager Identities: Culture, Philosophy and Professional Practice

    Science.gov (United States)

    Foley, Annette

    2011-01-01

    Using a post-structural approach this article investigates the working lives of frontline managers in VET and how they negotiate change in their day to day practices and decision making. The article is organised around accounts made by managers from different types of Vocational Education and Training (VET) organisations, namely: Technical and…

  11. Online Support for VET Clients: Expectations and Experiences.

    Science.gov (United States)

    Choy, Sarojni; McNickle, Cathy; Clayton, Berwyn

    Since little research existed about services for online learners in Australia, a national study was conducted to explore the expectations and experiences of online learners in the Vocational Education and Training (VET) sector. Online learners enrolled with various Registered Training Organizations (RTOs) from the VET sector were contacted for…

  12. Disadvantaged Learners and VET to Higher Education Transitions. Occasional Paper

    Science.gov (United States)

    Griffin, Tabatha

    2014-01-01

    The vocational education and training (VET) system can provide an entry point to the education sector for people who have experienced disadvantage in their lives. Participation in VET can provide personal benefits as well as lead to further study and/or employment. How disadvantaged learners participate in vocational education and training is an…

  13. VET Teachers in Europe: Policies, Practices and Challenges

    Science.gov (United States)

    Misra, Pradeep Kumar

    2011-01-01

    The objective of making vocational education and training (VET) globally competitive and attractive by the European Union has put vocational teachers in the spotlight. As a result, the VET teacher profession in Europe is facing many challenges and demands expressed constantly by the general public, representatives from the world of work, public…

  14. The Social Composition of VET in New Zealand

    Science.gov (United States)

    Strathdee, Rob

    2012-01-01

    This paper identifies three, overlapping, phases of restructuring of New Zealand's system of vocational education and training (VET). These are the meritocratic, the market and the managed. In very different ways, each phase has been designed to increase the propensity of students from all social backgrounds to participate in VET. This paper…

  15. Human Capital, HRD and VET: The Case of India

    Science.gov (United States)

    Tomé, Eduardo; Goyal, Apoorva

    2015-01-01

    Purpose: This paper aims to analyze the role of human capital (HC), human resource development (HRD) and vocational educational and training (VET) in the emerging Indian economy. How may we define the HC, HRD and VET in India? To what extent and how as HRD investments in India contributed to India's recent economic development? What were the…

  16. VET Leadership for the Future -- Characteristics, Contexts and Capabilities

    Science.gov (United States)

    Coates, Hamish; Meek, Lynn; Brown, Justin; Friedman, Tim; Noonan, Peter; Mitchell, John

    2013-01-01

    This paper examines leadership in Australia's vocational education and training (VET) sector. VET leaders make a vital and growing contribution to learners, industry and society, yet research on their work is limited. This has direct implications for ensuring leadership is most effective, and for framing evidence-based capacity development. The…

  17. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Ultrasound - Abdomen Children's (Pediatric) Ultrasound - Abdomen Obstetric Ultrasound Ultrasound - Prostate Kidney and Bladder Stones Abnormal Vaginal Bleeding Ovarian Cancer ...

  18. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Children's (Pediatric) Ultrasound - Abdomen Obstetric Ultrasound Ultrasound - Prostate Kidney and Bladder Stones Abnormal Vaginal Bleeding Ovarian Cancer Images related to Ultrasound - Pelvis Sponsored by Please ...

  19. BI-RADS lexicon: An urgent call for standardization of breast ...

    African Journals Online (AJOL)

    BI-RADS lexicon: An urgent call for standardization of breast ultrasound in Nigeria. MO Obajimi, OO Akute, AO Afolabi, AA Adenipekun, AO Oluwasola, EEU Akang, RU Joel, ATS Adeniji-Sofoluwe, O Funmi, G Newstead, R Schmitt, C Sennett ...

  20. What is the future of work based learning in VET?

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    Dual systems of vocational education and training that build on the tradition of apprenticeship have many attractive qualities, seen from a political perspective. VET systems that comprise a significant amount of work-based training, provide a valuable alternative for young people who chose...... with formal education in a dual system. But historically in many countries, apprenticeship has given way to school-based forms of VET and dual systems are only dominant in a limited number of countries. Furthermore, the integration of work-based training in an educational programme involves many challenges...... that question the future role and organisation of work-based training in VET. The purpose of this paper is to examine these challenges based on a review of research on European VET systems and analyses of the Danish dual system of VET. In the end of the paper, some innovative solutions to these challenges...

  1. What can be learned from the Nordic VET-systems?

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    school, no common model of upper secondary vocational education (VET) exist. Though these countries share the ideals of social inclusion and equal educational opportunities for all, they include two opposite models of VET. Sweden has realised the unified Gymnasium for all, comprising academic...... and vocational programmes that offer all students eligibility for higher education. Denmark has maintained a selective upper secondary school education and a VET-system based on the apprenticeship model. Finland and Norway represent mixed systems that combine elements from these system. By comparing VET......-systems in the Nordic countries, we have found that they represent different solutions to common basic trade-offs for VET. The unified Swedish system has given priority to secure equal access for all young people to higher education, but it has weak connections to the labour market. It is not very inclusive for young...

  2. Long Term RadNet Quality Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — This RadNet Quality Data Asset includes all data since initiation and when ERAMS was expanded to become RadNet, name changed to reflect new mission. This includes...

  3. Evidence for simultaneous protein interactions between human Rad51 paralogs.

    Science.gov (United States)

    Schild, D; Lio, Y C; Collins, D W; Tsomondo, T; Chen, D J

    2000-06-02

    In yeast, the Rad51-related proteins include Rad55 and Rad57, which form a heterodimer that interacts with Rad51. Five human Rad51 paralogs have been identified (XRCC2, XRCC3, Rad51B/Rad51L1, Rad51C/Rad51L2, and Rad51D/Rad51L3), and each interacts with one or more of the others. Previously we reported that HsRad51 interacts with XRCC3, and Rad51C interacts with XRCC3, Rad51B, and HsRad51. Here we report that in the yeast two-hybrid system, Rad51D interacts with XRCC2 and Rad51C. No other interactions, including self-interactions, were found, indicating that the observed interactions are specific. The yeast Rad51 interacts with human Rad51 and XRCC3, suggesting Rad51 conservation since the human yeast divergence. Data from yeast three-hybrid experiments indicate that a number of the pairs of interactions between human Rad51 paralogs can occur simultaneously. For example, Rad51B expression enhances the binding of Rad51C to XRCC3 and to HsRad51D, and Rad51C expression allows the indirect interaction of Rad51B with Rad51D. Experiments using 6xHis-tagged proteins in the baculovirus system confirm several of our yeast results, including Rad51B interaction with Rad51D only when Rad51C is simultaneously expressed and Rad51C interaction with XRCC2 only when Rad51D is present. These results suggest that these proteins may participate in one complex or multiple smaller ones.

  4. Prostate Ultrasound

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Ultrasound - Prostate Ultrasound of the prostate uses sound waves ... the limitations of Prostate Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is safe and ...

  5. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Ultrasound - Pelvis Ultrasound imaging of the pelvis uses sound ... limitations of Pelvic Ultrasound Imaging? What is Pelvic Ultrasound Imaging? Ultrasound is safe and painless, and produces ...

  6. Prostate Ultrasound

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z Ultrasound - Prostate Ultrasound of the prostate uses sound waves to ... Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is safe and painless, and produces pictures ...

  7. MyHealtheVet (VA's personal health record)

    Science.gov (United States)

    ... Orange, My HealtheVet and Online Help During the Vietnam War, the military used Agent Orange. Years later, some Veterans experience health effects potentially related to Agent Orange. View » Don't ...

  8. Risky Behavior Triggers Vicious Cycle for Vets with PTSD

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_166852.html Risky Behavior Triggers Vicious Cycle for Vets With PTSD Report ... 2017 FRIDAY, June 23, 2017 (HealthDay News) -- Reckless behavior could worsen post-traumatic stress disorder (PTSD) in ...

  9. Education - employment partnership for VET in the fashion sector

    Science.gov (United States)

    Ursache, M.; Avădanei, M. L.; Ionesi, D. S.; Loghin, E.

    2017-10-01

    The paper presents the objectives, the innovative aspects, the planned outputs and the current results of the project entitled “Education - Employment Partnership for VET in the fashion sector”. The project is co-financed by the European Commission under the Erasmus+ Programme, Key Action 2 - Strategic Partnerships in the Field of Education, Training, Youth and Sport. The project aims mainly the at developing a European teaching and training Toolkit for supporting the implementation of Work-Based Learning (WBL) in all stages of vocational education and training (VET) in the fashion sector. Moreover, the project will support the implementation of quality assurance mechanisms for WBL in VET in the fashion sector with a specific focus on feedback loops between iVET and cVET systems. The project consortium is composed by nine partners from four countries (Romania, Bulgaria, Italy and Netherlands) representing two iVET providers, a university a Chamber of Commerce, a Federation of SMEs connected with fashion industries, one research institution, one company in clothing and fashion sector, two consulting companies with experience in education and training policies. The actual research results presented in the paper are based on the survey oriented to the training needs and the impact and benefits of WBL implementation. The data were collected from educational organizations. Also, examples of good practices showing the different challenges and benefits of WBL implementation, were identified.

  10. Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination

    OpenAIRE

    Taylor, Martin R.G.; Špírek, Mário; Chaurasiya, Kathy R.; Ward, Jordan D.; Carzaniga, Raffaella; Yu, Xiong; Egelman, Edward H.; Collinson, Lucy M.; Rueda, David; Krejci, Lumir; Boulton, Simon J.

    2015-01-01

    Summary Repair of DNA double strand breaks by homologous recombination (HR) is initiated by Rad51 filament nucleation on single-stranded DNA (ssDNA), which catalyzes strand exchange with homologous duplex DNA. BRCA2 and the Rad51 paralogs are tumor suppressors and critical mediators of Rad51. To gain insight into Rad51 paralog function, we investigated a heterodimeric Rad51 paralog complex, RFS-1/RIP-1, and uncovered the molecular basis by which Rad51 paralogs promote HR. Unlike BRCA2, which ...

  11. MSL-RAD Cruise Operations Concept

    Science.gov (United States)

    Brinza, David E.; Zeitlin, Cary; Hassler, Donald; Weigle, Gerald E.; Boettcher, Stephan; Martin, Cesar; Wimmer-Schweingrubber, Robert

    2012-01-01

    The Mars Science Laboratory (MSL) payload includes the Radiation Assessment Detector (RAD) instrument, intended to fully characterize the radiation environment for the MSL mission. The RAD instrument operations concept is intended to reduce impact to spacecraft resources and effort for the MSL operations team. By design, RAD autonomously performs regular science observations without the need for frequent commanding from the Rover Compute Element (RCE). RAD operates with pre-defined "sleep" and "observe" periods, with an adjustable duty cycle for meeting power and data volume constraints during the mission. At the start of a new science observation, RAD performs a pre-observation activity to assess count rates for selected RAD detector elements. Based on this assessment, RAD can enter "solar event" mode, in which instrument parameters (including observation duration) are selected to more effectively characterize the environment. At the end of each observation period, RAD stores a time-tagged, fixed length science data packet in its non-volatile mass memory storage. The operating cadence is defined by adjustable parameters, also stored in non-volatile memory within the instrument. Periodically, the RCE executes an on-board sequence to transfer RAD science data packets from the instrument mass storage to the MSL downlink buffer. Infrequently, the RAD instrument operating configuration is modified by updating internal parameter tables and configuration entries.

  12. Sustainability Assessment Framework for VET Organizations

    Directory of Open Access Journals (Sweden)

    Liviu Moldovan

    2015-06-01

    Full Text Available This paper presents a new and innovative approach to assessing Vocational Education and Training (VET organizations institutional sustainability in terms of five key pillars: institutional capacity, environmental, economic, social, and training provision. In the five areas of the proposed new and original sustainability assessment framework, a total of 40 performance indicators are used to make the assessment. The assessment process is based on a novel approach for the couple values for performance and importance of the indicators, by using scales from 1 to 5 for both. There are five performance categories (awareness, measures, action, innovation and excellence and five importance categories for each indicator. The framework is innovative, both by its objective, which consists in impact determining and improvement on environmental, economic, social and quality of the training system and by development of a strategy based on performance indicators that integrates sustainable development. The implementation methodology is based on the newly developed framework and detailed application guidelines are provided. Exact results from a case study carried out and an analysis of the results for the environmental area are presented in order to validate the methodology in action. The results are used to establish a sustainability baseline, to identify possibilities for improvement, and to prioritize implementation.

  13. Prostate Ultrasound

    Medline Plus

    Full Text Available ... through blood vessels. Ultrasound imaging is a noninvasive medical test that helps physicians diagnose and treat medical conditions. Prostate ultrasound, also called transrectal ultrasound, provides ...

  14. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... are the limitations of Pelvic Ultrasound Imaging? What is Pelvic Ultrasound Imaging? Ultrasound is safe and painless, ... top of page What are some common uses of the procedure? In women, a pelvic ultrasound is ...

  15. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Ultrasound - Pelvis Ultrasound imaging of the pelvis uses sound waves to produce pictures of the structures and ... pictures of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or ...

  16. Prostate Ultrasound

    Medline Plus

    Full Text Available ... Z Ultrasound - Prostate Ultrasound of the prostate uses sound waves to produce pictures of a man’s prostate ... pictures of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or ...

  17. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Radiation Therapy for Gynecologic Cancers Radiation Therapy for Prostate Cancer top of page This page was reviewed on ... Abdomen Children's (Pediatric) Ultrasound - Abdomen Obstetric Ultrasound Ultrasound - Prostate Kidney and Bladder Stones ... to Ultrasound - Pelvis Videos related to ...

  18. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... 3-D ultrasound or sonohysterography for patients with infertility. In this setting, three-dimensional ultrasound provides information ... Ultrasound page for more information. In men and women, a pelvic ultrasound exam can help identify: kidney ...

  19. Prostate Ultrasound

    Medline Plus

    Full Text Available ... Ultrasound - Prostate Ultrasound of the prostate uses sound waves to produce pictures of a man’s prostate gland ... of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or sonography , ...

  20. Prostate Ultrasound

    Medline Plus

    Full Text Available ... Prostate Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is safe and painless, and produces ... of page What are some common uses of the procedure? A transrectal ultrasound of the prostate gland ...

  1. Characteristics of PI-RADS 4 lesions within the prostatic peripheral zone: a retrospective diagnostic accuracy study evaluating 170 lesions.

    Science.gov (United States)

    Shankar, Prasad R; Curci, Nicole E; Davenport, Matthew S

    2017-12-02

    To determine whether peripheral zone PI-RADS 4 observations can be further risk-stratified. This was an IRB-approved HIPAA-compliant retrospective diagnostic accuracy study. Peripheral zone PI-RADS 4 observations prospectively identified at the study institution from 8/1/2015 to 12/31/2016 (n = 170 in 149 mpMRIs) were reviewed independently by two blinded genitourinary radiologists on the basis of (a) PI-RADS v2 shape, (b) pattern of peripheral zone sparing, and (c) rationale for PI-RADS 4 designation. Reference standard was targeted MR-ultrasound fusion biopsy and detection of Gleason 7+ prostate cancer. Positive predictive values (PPVs) were calculated. Predictors were assessed with binary logistic regression. PI-RADS 4 lesions with a DWI score of 4 were more likely to represent Gleason 7+ prostate cancer (p = 0.008-0.01; Reader 1 PPV: 53%; Reader 2 PPV: 48%). Pattern of peripheral zone sparing and most lesion shapes were not predictive (p > 0.05); however, oval lesions were predictive for Reader 1 (PPV = 59%, p = 0.03) and lentiform lesions were predictive for Reader 2 (PPV = 74%, p = 0.01). Lesions scored as "not meeting PI-RADS 4 criteria" had significantly lower PPV (p = 0.016-0.003; Reader 1 PPV: 14%, Reader 2 PPV: 16%). Peripheral zone PI-RADS 4 lesions with a DWI score of 4 are more likely Gleason 7+ cancer than those with a DWI score of 3. Lesions overcalled as PI-RADS 4 have PPV similar to published PI-RADS 3 data. Lesion shape and peripheral zone sparing in general do not predict Gleason 7+ cancer within PI-RADS 4 observations.

  2. Find Recycling Facilities Servicing RAD Partners

    Science.gov (United States)

    RAD partners help protect the ozone layer and reduce emissions of greenhouse gases by disposing of older, inefficient refrigerated appliances using the best environmental practices and technologies available.

  3. Humans Need Not Apply: Robotization of Kepler Planet Candidate Vetting

    Science.gov (United States)

    Coughlin, Jeffrey; Mullally, Fergal; Thompson, Susan E.; Kepler Team

    2015-01-01

    Until now, the vast majority of Kepler planet candidate vetting has been performed by a dedicated team of humans. While human expertise has been invaluable in understanding the nuances of Kepler data, human vetting is very time-consuming and can be inconsistent. Over 20,000 threshold crossing events have been produced by the latest pipeline run on all 17 quarters of Kepler mission data, and many more artificial planet transits have been injected to estimate completeness. Given these large numbers, human vetting is no longer feasible on a reasonable time-scale, and would be difficult to characterize. We have created automated vetting programs known as "robovetters" that are specifically designed to mimic the decision-making process employed by the humans. They analyze both the light curve and pixel-level data in order to produce specific reasons for identifying false positives. We present benchmark tests on the Q1-Q16 Kepler planet catalog, which was vetted by humans, and present preliminary robovetter results based on a recent transit-search of the newly reprocessed Q1-Q17 data set.

  4. RAD51AP2, a novel vertebrate- and meiotic-specific protein, sharesa conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51

    Energy Technology Data Exchange (ETDEWEB)

    Kovalenko, Oleg V.; Wiese, Claudia; Schild, David

    2006-07-25

    Many interacting proteins regulate and/or assist the activities of RAD51, a recombinase which plays a critical role in both DNA repair and meiotic recombination. Yeast two-hybrid screening of a human testis cDNA library revealed a new protein, RAD51AP2 (RAD51 Associated Protein 2), that interacts strongly with RAD51. A full-length cDNA clone predicts a novel vertebrate specific protein of 1159 residues, and the RAD51AP2 transcript was observed only in meiotic tissue (i.e. adult testis and fetal ovary), suggesting a meiotic-specific function for RAD51AP2. In HEK293 cells the interaction of RAD51 with an ectopically-expressed recombinant large fragment of RAD51AP2 requires the C-terminal 57 residues of RAD51AP2. This RAD51-binding region shows 81% homology to the C-terminus of RAD51AP1/PIR51, an otherwise totally unrelated RAD51-binding partner that is ubiquitously expressed. Analyses using truncations and point mutations in both RAD51AP1 and RAD51AP2 demonstrate that these proteins use the same structural motif for RAD51 binding. RAD54 shares some homology with this RAD51-binding motif, but this homologous region plays only an accessory role to the adjacent main RAD51-interacting region, which has been narrowed here to 40 amino acids. A novel protein, RAD51AP2, has been discovered that interacts with RAD51 through a C-terminal motif also present in RAD51AP1.

  5. Physical mapping and cloning of RAD56

    DEFF Research Database (Denmark)

    Mathiasen, David P; Gallina, Irene; Germann, Susanne Manuela

    2013-01-01

    Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, bu...

  6. Dropout in VET – institutional selection and social exclusion

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    Dropout – institutional selection and social exclusion For the last ten years dropout of vocational education has increased strongly in Denmark. The questions addressed in this paper are why and how dropout in VET takes place. The objective is to provide more detailed and qualified knowledge...... of the complex processes of dropping out. The present study is part of a large national research project on retention in VET. The paper aims to understand dropout as a result of the interplay of students’ agentic actions and social interactions and the opportunities for participation afforded by the colleges...

  7. VET and the creative epistemology of the hand

    DEFF Research Database (Denmark)

    Tanggaard, Lene

    , and to collaborate across the value chains in our organisations. This developing situation should attract the attention of those involved in VET. This keynote presentation will link crafts, vocational education and training and creativity which have a lot in common. In this, the pragmatist idea of an epistemology...... with practical action. We should count something as knowledge only if it enables us to make a fruitful difference to human experience. This links with an understanding of creative actions as those actions that make an impact in and on the world. A practical implication of this would be that VET must teach its...

  8. Differential Diagnosis of Breast Category 3 and 4 Nodules Through BI-RADS Classification in Conjunction with Shear Wave Elastography.

    Science.gov (United States)

    Wang, Min; Yang, Zhi; Liu, Can; Yan, Junhong; Zhang, Wenxiao; Sun, Jian; Cui, Guanghe

    2017-03-01

    Ultrasound (US) has become one of the important imaging methods for differentiating benign from malignant breast lesions. In 2013, the American College of Radiology published the fifth edition of the Breast Imaging-Reporting and Data System (BI-RADS). BI-RADS is a guide with recommendations for the standardization of breast imaging (US, mammography and magnetic resonance imaging) reports and for the auditing of centers employing such methods. Its objective is to standardize the nomenclature used in the reports. However, current US examinations are neither adequately sensitive nor sufficiently specific enough. The average Young's modulus was measured through shear wave elastography (SWE) to evaluate the diagnostic value of the BI-RADS classification in conjunction with SWE in differentiating BI-RADS 3 and 4 nodules. A total of 100 consecutive women with 126 breast lesions, including 65 benign and 61 malignant lesions, were included. The average Young's modulus of breast nodules and peri-nodule tissue (Emean1 and Emean2) was also determined through SWE. A receiver operating characteristic curve was drawn on the basis of pathologic results. The highest cut-off values were C1 and C2. At Emean1 > C1 or Emean2 > C2, BI-RADS 3 was increased to 4a and BI-RADS 4a was increased to 4b. At Emean1 ≤ C1 and Emean2 ≤ C2, BI-RADS 4b was decreased to 4a. Other BI-RADS classifications remained unchanged. BI-RADS 3 and 4a were considered benign. BI-RADS 4b and 4c were malignant. The area under the curve, sensitivity and specificity of the BI-RADS classification in conjunction with SWE were 0.952, 93.4% and 95.4%, respectively. The area under the curve, sensitivity and specificity of the original BI-RADS classification were 0.883, 82.0% and 87.7%, respectively. Differences were statistically significant (p = 0.028, Z-test). The diagnostic sensitivity and specificity were increased effectively. As a new method, BI-RADS classification in conjunction with SWE that

  9. Initial Training for VET Teachers: A Portrait within a Larger Canvas

    Science.gov (United States)

    Guthrie, Hugh; McNaughton, Alicen; Gamlin, Tracy

    2011-01-01

    This study focuses on a critical aspect of the vocational education and training (VET) workforce: initial VET teacher training. It has identified the generic teacher education courses offered both by the VET and higher education sectors, ranging from the Certificate IV in Training and Assessment (now the Certificate IV in Training and Education)…

  10. 78 FR 31999 - 30-Day Notice of Proposed Information Collection: Iran Democracy Program Grants Vetting

    Science.gov (United States)

    2013-05-28

    ... Notice of Proposed Information Collection: Iran Democracy Program Grants Vetting ACTION: Notice of...: Iran Program Grants Vetting. OMB Control Number: 1405-0176. Type of Request: Extension. ] Originating... conduct this vetting, the Department collects information from grantees and sub-grantees regarding the...

  11. 75 FR 25307 - 30-Day Notice of Proposed Information Collection: DS-4100, Iran Program Grants Vetting...

    Science.gov (United States)

    2010-05-07

    ... Notice of Proposed Information Collection: DS-4100, Iran Program Grants Vetting, Information Collection... Department conduct a vetting of potential Iran programs grantees and sub-grantees for counter-terrorism purposes. To conduct this vetting the Department envisions collecting information from grantees and sub...

  12. 78 FR 15798 - 60-Day Notice of Proposed Information Collection: Iran Democracy Program Grants Vetting

    Science.gov (United States)

    2013-03-12

    ... Notice of Proposed Information Collection: Iran Democracy Program Grants Vetting ACTION: Notice of... to conduct vetting of potential Iran ] program grantees and sub-grantees for counter-terrorism purposes. To conduct this vetting, the Department collects information from grantees and sub-grantees...

  13. From VET School to the Labour Market in Bosnia and Herzegovina: Expected versus Actual Wages

    Science.gov (United States)

    Brankovic, Nina; Oruc, Nermin

    2016-01-01

    This article analyses the differences between expected and actual wages of VET students and graduates. It uses a survey of VET students enrolled in schools in Bosnia and Herzegovina, and data about employed VET graduates from the Labour Force Survey. The model of determinants of wages, expected or actual, estimated separately on each dataset,…

  14. A Preliminary Analysis of the Outcomes of Students Assisted by VET FEE-HELP: Summary

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2015

    2015-01-01

    This summary highlights the key findings from the report "A preliminary analysis of the outcomes of students assisted by VET FEE-HELP". VET FEE-HELP is an income-contingent loan scheme that assists eligible students undertaking certain vocational education training (VET) courses with an approved provider by paying for all or part of…

  15. 75 FR 2181 - 60-Day Notice of Proposed Information Collection: DS-4100, Iran Program Grants Vetting...

    Science.gov (United States)

    2010-01-14

    ... Notice of Proposed Information Collection: DS-4100, Iran Program Grants Vetting, Information Collection... Foreign Assets Control (OFAC) mandates that the Department conduct a vetting of potential Iran programs grantees and sub-grantees for counter-terrorism purposes. To conduct this vetting the Department envisions...

  16. Continuing Professional Development for a Diverse VET Practitioner Workforce. Occasional Paper

    Science.gov (United States)

    Tyler, Mark; Dymock, Darryl

    2017-01-01

    This occasional paper provides a stocktake of recent developments in continuing professional development for VET practitioners. It explores issues such as industry currency, the debate around a professional association for VET and the Certificate IV in Training and Assessment as the minimum qualification for VET practitioners. Through synthesising…

  17. Entry to Vocations: The Efficacy of VET in Schools. Research Report

    Science.gov (United States)

    Clarke, Kira

    2012-01-01

    Recent policy changes have facilitated an expanded role for VET in Schools in supporting school completion, with vocational education and training (VET) in schools qualifications and subjects receiving increasing recognition in senior secondary certificates. Despite increased attainment of VET qualifications amongst 15 to 19-year-olds (Australian…

  18. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... kidney stones bladder tumors other disorders of the urinary bladder In children, pelvic ultrasound can help evaluate: pelvic ... Ultrasound - Abdomen Obstetric Ultrasound Ultrasound - Prostate Kidney and Bladder Stones Abnormal Vaginal Bleeding ... Images related to Ultrasound - Pelvis Sponsored by Please ...

  19. Evidence that the Rad1 and Rad10 proteins of Saccharomyces cerevisiae participate as a complex in nucleotide excision repair of UV radiation damage.

    OpenAIRE

    Siede, W.; Friedberg, A S; Friedberg, E C

    1993-01-01

    A newly characterized rad1 missense mutation (rad1-20) in the yeast Saccharomyces cerevisiae maps to a region of the Rad1 polypeptide known to be required for Rad1-Rad10 complex formation. The UV sensitivity of the rad1-20 mutant can be partially and specifically corrected by overexpression of wild-type Rad10 protein. These results suggest that complex formation between the Rad1 and Rad10 proteins is required for nucleotide excision repair.

  20. Moral Learning for the Workplace: A Role for VET

    Science.gov (United States)

    James, Ian

    2012-01-01

    The paper explores ways that vocational education and training (VET) might become involved in the development of moral "know-how", ready for workplace practice. The primary concern here is the transformation of earlier-learnt ethical principles to their applied moral behaviour, essential for appropriate practice within workplace…

  1. Globalisation and Its Impact on VET. Review of Research.

    Science.gov (United States)

    Hobart, Barry

    The impact of globalization on vocational education and training (VET) in Australia was examined through a literature review. Special attention was paid to the following topics: the growing export orientation in Australian industry (industrial growth in Australia's economy, growth in Australian exports, "knowledge intensity" in the…

  2. VET in Schools 2016: Terms and Definitions. Support Document

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2017

    2017-01-01

    This document covers the data terms used in the "VET in Schools 2016" summary publication. The primary purpose of this document is to assist users to understand the specific data terms. Terms that appear in the publication are listed in alphabetical order with the following information provided for each: (1) definition: a brief…

  3. VET Provider Market Structures: History, Growth and Change. Research Report

    Science.gov (United States)

    Korbel, Patrick; Misko, Josie

    2016-01-01

    This paper tracks the development of the Australian vocational education and training (VET) provider market over the last two decades in the context of significant policy changes and generally increased competition. It provides an insight into how the sector has arrived at its current position, painting a present-day picture of great diversity.…

  4. The Modularisation Approach of Work-Based VET in Scotland

    Science.gov (United States)

    Pilz, Matthias; Canning, Roy

    2017-01-01

    The issue of modularising vocational education and training (VET) systems has been the subject of heated debate in many European countries. In particular, in Scotland the use of modules within the curriculum has been seen as either restrictive or liberating depending upon the theoretical stance taken. At a more pragmatic level modularisation of…

  5. Analysis of VET in Ukraine Since the Soviet Era

    Science.gov (United States)

    Zinser, Richard

    2015-01-01

    Purpose: The purpose of this paper is to explore how vocational education and training (VET) in Ukraine has changed since the Soviet era; and to determine its structure, successes, and challenges. Design/methodology/approach: The author conducted interviews and tours at 15 vocational schools in seven cities in Ukraine. Findings: Ukraine is…

  6. Reforming vocational didactics by implementing a new VET teacher education

    DEFF Research Database (Denmark)

    Duch, Henriette; Andreasen, Karen Egedal

    2015-01-01

    A new education program, Diploma of Vocational Pedagogy, has recently been implemented in Denmark to upskill vocational college teachers and improve didactics at VET colleges in general. Among many challenges, vocational college teachers have to adapt their pedagogy to a large number of students...

  7. Quality in the Australian VET Sector: What Has Been Happening?

    Science.gov (United States)

    Harris, Roger

    2015-01-01

    VET (vocational education and training) is a fascinating sector. Aligned closely with the labour market and sandwiched between two major sectors, it is continually buffeted by political winds, susceptible to the ideologies of different governments. Often labelled the "poor cousin", debates continue to rage about its quality. This paper…

  8. Making Sense of Total VET Activity: An Initial Market Analysis

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2016

    2016-01-01

    Following the successful first national publication of total vocational education and training (VET) activity and presentation of various informative data products, NCVER has continued to undertake further analysis of the submitted data. This paper is the first in a suite of the National Centre for Vocational Education Research (NCVER) authored…

  9. VET in Schools 2008: Terms and Definitions. Support Document

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2010

    2010-01-01

    This document covers the data terms used in the "VET in Schools 2008" report. The primary purpose of this document is to assist users of the report to understand the specific data terms used within it. Terms that appear in the report are listed in alphabetical order with the following information provided for each: (1) Definition: a…

  10. 77 FR 8166 - Partner Vetting in USAID Acquisitions

    Science.gov (United States)

    2012-02-14

    ... contract will there be a post-award requirement for vetting. Response: USAID agrees that a contract must...: ``Task order competitions under Indefinite Quantity Contracts (IQC) always come `post-award' of the... contracts. We strongly recommend that the treatment of task orders under IQCs be addressed in this post...

  11. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... ultrasound images are captured in real-time, they can show the structure and movement of the body's ... Obstetrical Ultrasound page for more information . Ultrasound examinations can help diagnose symptoms experienced by women such as: ...

  12. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... endovaginal ) for women rectal ( transrectal ) for men A Doppler ultrasound exam may be part of a pelvic ultrasound examination. Doppler ultrasound , also called color Doppler ultrasonography, is a ...

  13. Prostate Ultrasound

    Medline Plus

    Full Text Available ... What are the limitations of Prostate Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is safe and painless, and produces pictures of the inside of the body using ...

  14. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... What are the limitations of Pelvic Ultrasound Imaging? What is Pelvic Ultrasound Imaging? Ultrasound is safe and painless, and produces pictures of the inside of the body using ...

  15. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... ultrasound exams are also used to monitor the health and development of an embryo or fetus during pregnancy. See the Obstetrical Ultrasound page for more information . Ultrasound examinations can help diagnose symptoms experienced by ...

  16. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... a pelvic ultrasound examination. Doppler ultrasound , also called color Doppler ultrasonography, is a special ultrasound technique that ... and processes the sounds and creates graphs or color pictures that represent the flow of blood through ...

  17. Obstetrical Ultrasound

    Science.gov (United States)

    ... are similar to sonar used by boats and submarines. The ultrasound image is immediately visible on a ... has been described by patients as a whooshing noise. Doppler ultrasound, a special application of ultrasound, measures ...

  18. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... What are the limitations of Pelvic Ultrasound Imaging? What is Pelvic Ultrasound Imaging? Ultrasound is safe and ... as the liver or kidneys. top of page What are some common uses of the procedure? In ...

  19. Prostate Ultrasound

    Medline Plus

    Full Text Available ... What are the limitations of Prostate Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is ... in front of the rectum. top of page What are some common uses of the procedure? A ...

  20. Intravascular ultrasound

    Science.gov (United States)

    IVUS; Ultrasound - coronary artery; Endovascular ultrasound; Intravascular echocardiography ... A tiny ultrasound wand is attached to the top of a thin tube. This tube is called a catheter. The catheter ...

  1. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Pelvis Ultrasound imaging of the pelvis uses sound waves to produce pictures of the structures and organs ... of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or sonography , ...

  2. Prostate Ultrasound

    Medline Plus

    Full Text Available ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ... other imaging methods. Ultrasound imaging uses no ionizing radiation. Ultrasound scanning may be able to give a ...

  3. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... ultrasound exams are also used to monitor the health and development of an embryo or fetus during pregnancy. See the Obstetrical Ultrasound page for more information . Ultrasound examinations can help diagnose symptoms experienced by women such ...

  4. Transvaginal ultrasound

    Science.gov (United States)

    ... ultrasound; Menstrual bleeding - transvaginal ultrasound; Infertility - transvaginal ultrasound; Ovarian - transvaginal ... benign and malignant epithelial and germ cell neoplasms, sex-cord stromal tumors. In: Lentz GM, Lobo RA, Gershenson DM, ...

  5. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... three types of pelvic ultrasound: abdominal, vaginal (for women), and rectal (for men). These exams are frequently ... pelvic ultrasound: abdominal ( transabdominal ) vaginal ( transvaginal / endovaginal ) for women rectal ( transrectal ) for men A Doppler ultrasound exam ...

  6. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... through blood vessels. Ultrasound imaging is a noninvasive medical test that helps physicians diagnose and treat medical conditions. There are three types of pelvic ultrasound: ...

  7. RadNet Air Quality (Deployable) Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet Deployable Monitoring is designed to collect radiological and meteorological information and data asset needed to establish the impact of radiation levels on...

  8. 20 CFR 1002.291 - What actions may an individual take if the complaint is not resolved by VETS?

    Science.gov (United States)

    2010-04-01

    ... complaint is not resolved by VETS? 1002.291 Section 1002.291 Employees' Benefits OFFICE OF THE ASSISTANT... VETS? If an individual receives a notification from VETS of an unsuccessful effort to resolve his or her complaint relating to a State or private employer, the individual may request that VETS refer the...

  9. Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures

    Energy Technology Data Exchange (ETDEWEB)

    Vries, Femke A.T. de [Department of Toxicogenetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden (Netherlands); Zonneveld, Jose B.M. [Department of Toxicogenetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden (Netherlands); Groot, Anton J. de [Department of Toxicogenetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden (Netherlands); Koning, Roman I. [Department of Molecular Cell Biology, Leiden University Medical Center, Leiden (Netherlands); Zeeland, Albert A. van [Department of Toxicogenetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden (Netherlands); Pastink, Albert [Department of Toxicogenetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden (Netherlands)]. E-mail: A.Pastink@lumc.nl

    2007-02-03

    The Saccharomyces cerevisiae Rad52 protein has a crucial role in the repair of DNA double-strand breaks by homologous recombination. In vitro, Rad52 displays DNA binding and strand annealing activities and promotes Rad51-mediated strand exchange. Schizosaccharomyces pombe has two Rad52 homologues, Rad22A and Rad22B. Whereas rad22A deficient strains exhibit severe defects in repair and recombination, rad22B mutants have a much less severe phenotype. To better understand the role of Rad22A and Rad22B in double-strand break repair, both proteins were purified to near homogeneity. Using gel retardation and filter binding assays, binding of Rad22A and Rad22B to short single-stranded DNAs was demonstrated. Binding of Rad22A to double-stranded oligonucleotides or linearized plasmid molecules containing blunt ends or short single-stranded overhangs could not be detected. Rad22B also does not bind efficiently to short duplex oligonucleotides but binds readily to DNA fragments containing 3'-overhangs. Rad22A as well as Rad22B efficiently promote annealing of complementary single-stranded DNAs. In the presence of Rad22A annealing of complementary DNAs is almost 90%. Whereas in reactions containing Rad22B the maximum level of annealing is 60%, most likely due to inhibition of the reaction by duplex DNA. Gel-filtration experiments and electron microscopic analyses indicate self-association of Rad22A and Rad22B and the formation of multimeric structures as has been observed for Rad52 in yeast and man.

  10. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Radiation Therapy for Gynecologic Cancers Radiation Therapy for Prostate Cancer top of page This page was reviewed on ... Abdomen Children's (Pediatric) Ultrasound - Abdomen Obstetric Ultrasound Ultrasound - Prostate Kidney and Bladder ... Images related to Ultrasound - Pelvis Sponsored by Please ...

  11. Prostate Ultrasound

    Medline Plus

    Full Text Available ... are the limitations of Prostate Ultrasound Imaging? What is Ultrasound Imaging of the Prostate? Ultrasound is safe and painless, and produces ... top of page What are some common uses of the procedure? A transrectal ultrasound of the prostate ...

  12. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... both sexes without x-ray exposure. Risks For standard diagnostic ultrasound , there are no known harmful effects on humans. top of page What are the limitations of Pelvic Ultrasound Imaging? Ultrasound waves are disrupted by air or gas; therefore ultrasound is not an ideal ...

  13. Bottomonium suppression using a lattice QCD vetted potential

    Science.gov (United States)

    Krouppa, Brandon; Rothkopf, Alexander; Strickland, Michael

    2018-01-01

    We estimate bottomonium yields in relativistic heavy-ion collisions using a lattice QCD vetted, complex-valued, heavy-quark potential embedded in a realistic, hydrodynamically evolving medium background. We find that the lattice-vetted functional form and temperature dependence of the proper heavy-quark potential dramatically reduces the dependence of the yields on parameters other than the temperature evolution, strengthening the picture of bottomonium as QGP thermometer. Our results also show improved agreement between computed yields and experimental data produced in RHIC 200 GeV /nucleon collisions. For LHC 2.76 TeV /nucleon collisions, the excited states, whose suppression has been used as a vital sign for quark-gluon-plasma production in a heavy-ion collision, are reproduced better than previous perturbatively-motivated potential models; however, at the highest LHC energies our estimates for bottomonium suppression begin to underestimate the data. Possible paths to remedy this situation are discussed.

  14. Description of the TCERT Vetting Reports for Data Release 25

    Science.gov (United States)

    Coughlin, Jeffrey L,

    2017-01-01

    The Q1Q17 DR25 TCERT Vetting Reports are a collection of plots and diagnostics used by the Threshold Crossing Event Review Team (TCERT) to evaluate threshold crossing events (TCEs). While designation of Kepler Objects of Interest (KOIs) and classification of them as Planet Candidates (PCs) or False Positives (FPs) is completely automated via a robotic vetting procedure (the Robovetter) for the Q1Q17 DR25 planet catalog, as described in Thompson et al. (2017), these reports help to visualize the metrics used by the Robovetter and evaluate those robotic decisions for individual objects. For each Q1Q17 DR25 TCE, these reports include the following products: (a) the DV one-page summary, (b) selected pertinent diagnostics and plots from the full DV report, and (c) additional plots and diagnostics not included in the full DV report, including an alternate means of data detrending.

  15. Assessing the validity of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) scoring system in diagnosis of peripheral zone prostate cancer.

    Science.gov (United States)

    Dola, Eman F; Nakhla, Osama L; Genidi, Eman A Sh

    2017-01-01

    Assessing the accuracy of multi parametric magnetic resonance (mp-MRI) after application of PI-RADS V2 for diagnosis of prostate cancer as comparison to pathological results of trans rectal ultra-sound (TRUS) guided biopsy. 138 prostatic lesions in 23 patients were retrospectively assessed and analyzed with Trans rectal ultra-sound (TRUS) guided biopsy results. Those patients underwent multi parametric magnetic resonance (mp-MRI) with application of PI-RADS V2 reporting system. The sensitivity, specificity, validity, negative predictive value and positive predictive value were calculated for PI-RADS V2 reporting system compared to biopsy-proven pathological results. 92 out of 138 lesions were positive for Peripheral zone cancer prostate. PI-RADS V2 reporting system proved 88.04% sensitive & 93.4% specific for diagnosis of prostate cancer with negative predictive value & positive predictive value of 100%. Our results proved that mp-MRI of prostate using PI-RADS v2 scoring system had high sensitivity and specificity in diagnosis of prostate cancer and PI-RADS V2 scoring system using mp-MRI is recommended as a non-invasive diagnostic tool compared to TRUS guided biopsy.

  16. VetBact - culturing bacteriological knowledge for veterinarians

    OpenAIRE

    Johansson, Karl-Erik

    2014-01-01

    In 2004, Karl-Erik Johansson, then professor of veterinary bacteriology at the veterinary school at Uppsala in Sweden, was asked by his students for a list of the most important bacteria and the diseases that they cause. So began the development of VetBact, an online database giving details of the bacterial species with most relevance to veterinary medicine. The non-commercial database, www.vetbact.org, has since grown and can now be accessed by veterinarians and others worldwide.

  17. Vet Futures: taking account of the wider veterinary team.

    Science.gov (United States)

    2016-08-13

    A summit meeting held at the Royal Veterinary College in July saw the launch of an action plan to take forward the six key ambitions set out in the 2015 Vet Futures report. Developed by an action group following publication of the report, the plan outlines an ambitious programme of work. The summit also saw the launch of a VN Futures report setting out a vision for the veterinary nursing profession over the next five years. Laura Honey reports. British Veterinary Association.

  18. Quality Guidelines for Scalable Eco Skills in Vet Delivery

    Directory of Open Access Journals (Sweden)

    Liviu MOLDOVAN

    2016-06-01

    Full Text Available In a sustainable economy the assessment of Eco skills provided in a Vocational Education and Training (VET course is performed by the amount of knowledge applied on the job a period after the course ends. To this end VET providers have a current need of quality guidelines for scalable Eco skills and sustainable training evaluation. The purpose of the paper is to present some results of the project entitled “European Quality Assurance in VET towards new Eco Skills and Environmentally Sustainable Economy”, as regards Eco skills categorisation and elaboration of a scale to be used in the green methodology for learning assessment. In the research methodology, the Eco skills are categorised and exemplified for jobs at different levels into generic skills and specific skills evidenced from relevant publications in the field. Than the new Eco skills scale is developed which is organized into six steps: from “Level 1 - Introductory” up to “Level 6 - Expert”. The Eco skills scale is a useful input in the learning assessment process.

  19. SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination

    DEFF Research Database (Denmark)

    Silva, Sonia; Altmannova, Veronika; Eckert-Boulet, Nadine

    2016-01-01

    for survival after genotoxic stress, it affects the outcome of recombination to promote conservative DNA repair. In some genetic assays, Rad52 and Rad59 SUMOylation act synergistically. Collectively, our data indicate that the described SUMO modifications affect the balance between conservative and non......Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic. The post-translational modification by SUMO (small ubiquitin......-like modifier) has been shown to modulate recombination, but the exact mechanism of this regulation remains unclear. Here we show that SUMOylation stabilizes the interaction between the recombination mediator Rad52 and its paralogue Rad59 in Saccharomyces cerevisiae. Although Rad59 SUMOylation is not required...

  20. Efficacy study of Styplon Vet Bolus as supportive therapy in management of hemorrhagic conditions of ruminants

    Directory of Open Access Journals (Sweden)

    B R Ravikumar

    Full Text Available On-field trial was conducted in dairy animals to evaluate efficacy of Styplon Vet Bolus (M/s Himalaya Drug Company, Banglore, India as supportive therapy in management of hemorrhagic conditions (Hematuria, hemoagalectia, bleeding wounds, uterine bleeding and epistaxis of ruminants. Styplon Vet 1-2 boli twice daily was administered to cows and buffaloes, and ½ bolus twice daily for sheep till they recover clinically. The results indicated that Styplon Vet Bolus is a safe and effective styptic in ruminants. [Vet World 2009; 2(12.000: 470-471

  1. Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans.

    Directory of Open Access Journals (Sweden)

    Sreyoshi Mitra

    2014-04-01

    Full Text Available Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of centromere identity are not clearly defined. While multiple mechanisms, individually or in concert, may specify centromeres epigenetically, most studies in this area are focused on a universal factor, a centromere-specific histone H3 variant CENP-A, often considered as the epigenetic determinant of centromere identity. In spite of variable timing of its loading at centromeres across species, a replication coupled early S phase deposition of CENP-A is found in most yeast centromeres. Centromeres are the earliest replicating chromosomal regions in a pathogenic budding yeast Candida albicans. Using a 2-dimensional agarose gel electrophoresis assay, we identify replication origins (ORI7-LI and ORI7-RI proximal to an early replicating centromere (CEN7 in C. albicans. We show that the replication forks stall at CEN7 in a kinetochore dependent manner and fork stalling is reduced in the absence of the homologous recombination (HR proteins Rad51 and Rad52. Deletion of ORI7-RI causes a significant reduction in the stalled fork signal and an increased loss rate of the altered chromosome 7. The HR proteins, Rad51 and Rad52, have been shown to play a role in fork restart. Confocal microscopy shows declustered kinetochores in rad51 and rad52 mutants, which are evidence of kinetochore disintegrity. CENP-ACaCse4 levels at centromeres, as determined by chromatin immunoprecipitation (ChIP experiments, are reduced in absence of Rad51/Rad52 resulting in disruption of the kinetochore structure. Moreover, western blot analysis reveals that delocalized CENP-A molecules in HR mutants degrade in a similar fashion as in other kinetochore mutants described before. Finally, co-immunoprecipitation assays indicate that Rad51 and Rad52 physically interact with CENP-ACaCse4 in vivo. Thus, the HR proteins Rad51 and Rad52

  2. Prostate Ultrasound

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    Full Text Available ... abnormal growth within the prostate. help diagnose the cause of a man's infertility. A transrectal ultrasound of ... show up well on x-ray images. Ultrasound causes no health problems and may be repeated as ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... investigation of the uterine cavity . Three-dimensional (3-D) ultrasound permits evaluation of the uterus and ovaries ... abnormal uterine bleeding Some physicians also use 3-D ultrasound or sonohysterography for patients with infertility. In ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... kidneys. top of page What are some common uses of the procedure? In women, a pelvic ultrasound ... patients with abnormal uterine bleeding Some physicians also use 3-D ultrasound or sonohysterography for patients with ...

  5. Prostate Ultrasound

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    Full Text Available ... ultrasound images are captured in real-time, they can show the structure and movement of the body's ... Because ultrasound provides real-time images, it also can be used to guide procedures such as needle ...

  6. Prostate Ultrasound

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    Full Text Available ... as detailed as with the transrectal probe. An MRI of the pelvis may be obtained as an ... Enlargement of the Prostate) Prostate Cancer Ultrasound- and MRI-Guided Prostate Biopsy Images related to Ultrasound - Prostate ...

  7. Ultrasound -- Pelvis

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    Full Text Available ... and produces pictures of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound ... from the probe through the gel into the body. The transducer collects the sounds that bounce back ...

  8. Prostate Ultrasound

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    Full Text Available ... and produces pictures of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound ... from the probe through the gel into the body. The transducer collects the sounds that bounce back ...

  9. Prostate Ultrasound

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    Full Text Available ... gel. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... is at high risk for cancer. In this case, a biopsy is performed and an ultrasound probe ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... safe, noninvasive and does not use ionizing radiation. This procedure requires little to no special preparation. You ... ultrasound or sonohysterography for patients with infertility. In this setting, three-dimensional ultrasound provides information about the ...

  11. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... insertion. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media Sonohysterography Ultrasound - ...

  12. Ultrasound -- Pelvis

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    Full Text Available ... help diagnose symptoms experienced by women such as: pelvic pain abnormal vaginal bleeding other menstrual problems Ultrasound exams ... children, pelvic ultrasound can help evaluate: pelvic masses pelvic pain ambiguous genitalia and anomalies of pelvic organs early ...

  13. Ultrasound -- Pelvis

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    Full Text Available ... is used to evaluate the: bladder seminal vesicles prostate Transrectal ultrasound, a special study usually done to provide detailed evaluation of the prostate gland, involves inserting a specialized ultrasound transducer into ...

  14. Ultrasound -- Pelvis

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    Full Text Available ... insertion. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... modality for the diagnosis and monitoring of pregnant women and their unborn babies. Ultrasound provides real-time ...

  15. Ultrasound -- Pelvis

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    Full Text Available ... extract a sample of cells from organs for laboratory testing. Doppler ultrasound images can help the physician ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ...

  16. Ultrasound -- Pelvis

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    Full Text Available ... ultrasound: abdominal, vaginal (for women), and rectal (for men). These exams are frequently used to evaluate the ... vaginal ( transvaginal / endovaginal ) for women rectal ( transrectal ) for men A Doppler ultrasound exam may be part of ...

  17. Prostate Ultrasound

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    Full Text Available ... safe and painless, and produces pictures of the inside of the body using sound waves. Ultrasound imaging, ... to four hours before the ultrasound to clean out the bowel. top of page What does the ...

  18. Ultrasound -- Pelvis

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    Full Text Available ... tumors other disorders of the urinary bladder In children, pelvic ultrasound can help evaluate: pelvic masses pelvic pain ambiguous genitalia and anomalies of pelvic organs early or delayed puberty in girls Pelvic ultrasound is ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... for more information . Ultrasound examinations can help diagnose symptoms experienced by women such as: pelvic pain abnormal ... Ultrasound is the preferred imaging modality for the diagnosis and monitoring of pregnant women and their unborn ...

  20. Prostate Ultrasound

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    Full Text Available ... patient. Because ultrasound images are captured in real-time, they can show the structure and movement of ... test result. difficulty urinating. Because ultrasound provides real-time images, it also can be used to guide ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... patient. Because ultrasound images are captured in real-time, they can show the structure and movement of ... help to distract the child and make the time pass quickly. The ultrasound exam room may have ...

  2. Ultrasound -- Pelvis

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    Full Text Available ... needles are used to extract a sample of cells from organs for laboratory testing. Doppler ultrasound images ... ultrasound, measures the direction and speed of blood cells as they move through vessels. The movement of ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... as: pelvic pain abnormal vaginal bleeding other menstrual problems Ultrasound exams also help identify: palpable masses such ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... depth investigation of the uterine cavity . Three-dimensional (3-D) ultrasound permits evaluation of the uterus and ... with abnormal uterine bleeding Some physicians also use 3-D ultrasound or sonohysterography for patients with infertility. ...

  5. Ultrasound -- Pelvis

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    Full Text Available ... are also used to monitor the health and development of an embryo or fetus during pregnancy. See the Obstetrical Ultrasound page for more information . Ultrasound examinations can help diagnose symptoms experienced by ...

  6. Prostate Ultrasound

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    Full Text Available ... with your knees toward your chest. To obtain high-quality images, an ultrasound transducer – a plastic cylinder ... and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe ...

  7. Ultrasound -- Pelvis

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    Full Text Available ... vaginal (for women), and rectal (for men). These exams are frequently used to evaluate the reproductive and ... women rectal ( transrectal ) for men A Doppler ultrasound exam may be part of a pelvic ultrasound examination. ...

  8. Prostate Ultrasound

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    Full Text Available ... in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured ... standard diagnostic ultrasound , there are no known harmful effects on humans. top of page What are the ...

  9. Prostate Ultrasound

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    Full Text Available ... top of page What are the benefits vs. risks? Benefits Ultrasound is widely available, easy-to-use ... procedures such as needle biopsies and fluid aspiration. Risks For standard diagnostic ultrasound , there are no known ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... procedure work? Ultrasound imaging is based on the same principles involved in the sonar used by bats, ... of the images may also be saved. The same principles apply to ultrasound procedures such as transrectal ...

  11. Prostate Ultrasound

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    Full Text Available ... procedure work? Ultrasound imaging is based on the same principles involved in the sonar used by bats, ... of the images may also be saved. The same principles apply to ultrasound procedures such as transrectal ...

  12. Ultrasound -- Pelvis

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    Full Text Available ... diagnose symptoms experienced by women such as: pelvic pain abnormal vaginal bleeding other menstrual problems Ultrasound exams ... pelvic ultrasound can help evaluate: pelvic masses pelvic pain ambiguous genitalia and anomalies of pelvic organs early ...

  13. Prostate Ultrasound

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    Full Text Available ... evaluation with additional views or a special imaging technique. A follow-up examination may also be necessary ... to-use and less expensive than other imaging methods. Ultrasound imaging uses no ionizing radiation. Ultrasound scanning ...

  14. Ultrasound -- Pelvis

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    Full Text Available ... your child's favorite channel. top of page What does the equipment look like? Ultrasound scanners consist of ... and lubricated before insertion. top of page How does the procedure work? Ultrasound imaging is based on ...

  15. Prostate Ultrasound

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    Full Text Available ... clean out the bowel. top of page What does the equipment look like? Ultrasound scanners consist of ... lubricated with a gel. top of page How does the procedure work? Ultrasound imaging is based on ...

  16. Ultrasound -- Pelvis

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    Full Text Available ... 3-D ultrasound or sonohysterography for patients with infertility. In this setting, three-dimensional ultrasound provides information ... are sometimes the best way to see if treatment is working or if a finding is stable ...

  17. Prostate Ultrasound

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    Full Text Available ... may be instructed to use an enema to clean out your bowel. What is Ultrasound Imaging of ... two to four hours before the ultrasound to clean out the bowel. top of page What does ...

  18. Endoscopic ultrasound

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/007646.htm Endoscopic ultrasound To use the sharing features on this page, please enable JavaScript. Endoscopic ultrasound is a type of imaging test. It is ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... records tiny changes in the sound's pitch and direction. These signature waves are instantly measured and displayed ... ultrasound, a special application of ultrasound, measures the direction and speed of blood cells as they move ...

  20. Prostate Ultrasound

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    Full Text Available ... prostate gland while the radiologist watches the needle placement with ultrasound. A small amount of tissue is ... on x-ray images. Ultrasound causes no health problems and may be repeated as often as is ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... For most ultrasound exams, you will be positioned lying face-up on an examination table that can ... ovaries. Transvaginal ultrasound is usually performed with you lying on your back, possibly with your feet in ...

  2. Ultrasound -- Pelvis

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    Full Text Available ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ... extremely safe and does not use any ionizing radiation. Ultrasound scanning gives a clear picture of soft ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... bladder seminal vesicles prostate Transrectal ultrasound, a special study usually done to provide detailed evaluation of the ... time to the procedure. If a Doppler ultrasound study is performed, you may actually hear pulse-like ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... menstrual problems Ultrasound exams also help identify: palpable masses such as ovarian cysts and uterine fibroids ovarian ... In children, pelvic ultrasound can help evaluate: pelvic masses pelvic pain ambiguous genitalia and anomalies of pelvic ...

  5. Ultrasound -- Pelvis

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    Full Text Available ... of page What are some common uses of the procedure? In women, a pelvic ultrasound is most ... child's favorite channel. top of page What does the equipment look like? Ultrasound scanners consist of a ...

  6. Ultrasound -- Pelvis

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    Full Text Available ... ovarian cysts and uterine fibroids ovarian or uterine cancers A transvaginal ultrasound is usually performed to view the endometrium (the lining of the uterus) and the ovaries. Transvaginal ultrasound also evaluates the myometrium (muscular walls ...

  7. Prostate Ultrasound

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    Full Text Available ... chest. To obtain high-quality images, an ultrasound transducer – a plastic cylinder about the size of a ... or sonography , involves the use of a small transducer (probe) and ultrasound gel placed directly on the ...

  8. Ultrasound -- Pelvis

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    Full Text Available ... 3-D ultrasound or sonohysterography for patients with infertility. In this setting, three-dimensional ultrasound provides information ... move through vessels. The movement of blood cells causes a change in pitch of the reflected sound ...

  9. Prostate Ultrasound

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    Full Text Available ... obtain high-quality images, an ultrasound transducer – a plastic cylinder about the size of a finger – is ... end of their bowel (rectum) removed during prior surgery are not good candidates for ultrasound of the ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... transducer into the body. Doppler ultrasound, a special application of ultrasound, measures the direction and speed of ... following text box: Comment: E-mail: Area code: Phone no: Thank you! Do you have a personal ...

  11. Ultrasound -- Pelvis

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    Full Text Available ... transducer into the body. Doppler ultrasound, a special application of ultrasound, measures the direction and speed of ... care physician, or to the physician or other healthcare provider who requested the exam. Usually, the referring ...

  12. Prostate Ultrasound

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    Full Text Available ... Ultrasound provides real-time imaging, making it a good tool for guiding minimally invasive procedures such as ... bowel (rectum) removed during prior surgery are not good candidates for ultrasound of the prostate gland because ...

  13. Non-mass-like breast lesions at ultrasonography: Feature analysis and BI-RADS assessment

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Kai-Hsiung [Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC (China); Hsu, Hsian-He, E-mail: hsianhe@yahoo.com.tw [Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC (China); Yu, Jyh-Cherng [Department of Surgery, Division of General Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC (China); Peng, Yi-Jen [Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC (China); Tung, Ho-Jui [Department of Healthcare Administration, Asia University, Taichung, Taiwan, ROC (China); Chu, Chi-Ming [Section of Health Informatics, Institute of Public Health, National Defense Medical Center and University, Taipei, Taiwan, ROC (China); Chang, Tsun-Hou; Chang, Wei-Chou; Wu, Yu-Cheng; Lin, Yu-Pang; Hsu, Giu-Cheng [Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC (China)

    2015-01-15

    Highlights: • The positive predictive value of an NML lesion on ultrasound ranges from 10 to 79%. • A sizable number of NML malignant lesions are pure DCIS or ILC. • Biopsy is indicated for histopathological diagnosis when an ultrasound NML lesion is recognized. - Abstract: Objective: To analyze the features of non-mass-like (NML) breast lesions on ultrasound (US) and determine their corresponding malignancy rate and to stratify these lesion patterns according to US BI-RADS categories. Materials and methods: One hundred sixty-four consecutive lesions were retrospectively classified into four types according to the US features, the corresponding positive predictive values (PPVs) were obtained. Clinical, imaging, and histopathological findings were reviewed. Results: Among the 164 lesions, 39 (24%) were classified as type Ia, 14 (8%) as type Ib, 39 (24%) as type IIa, 19 (12%) as type IIb, 19 (12%) as type III, and 34 (21%) as type IV. The PPVs for malignancy were 21% for type Ia, 79% for type Ib, 10% for type IIa, 58% for type IIb, 16% for type III, and 21% for type IV. All NML lesions were classified as BI-RADS category 4a (type IIa), 4b (type Ia, III and IV) and 4c (type Ib and IIb) according to their PPVs. There was a significantly higher frequency of malignancy among lesions of type Ib and type IIb compared with the other types (P < 0.01 for each). Lesions with associated calcifications, presence of abnormal axillary nodes, or a mammographic finding of suspected malignancy had a higher probability of malignancy (P < 0.05 for each). Conclusion: US is useful in clarifying the indication for biopsy of NML lesions. The types of US classifications used in our study establish reliable references for the NML patterns when stratified according to the BI-RADS categories.

  14. RadNet Air Data From Little Rock, AR

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Little Rock, AR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  15. RadNet Air Data From Pittsburgh, PA

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Pittsburgh, PA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  16. RadNet Air Data From Montgomery, AL

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Montgomery, AL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  17. RadNet Air Data From Toledo, OH

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Toledo, OH from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  18. RadNet Air Data From Honolulu, HI

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Honolulu, HI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  19. RadNet Air Quality (Fixed Station) Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet is a national network of monitoring stations that regularly collect air for analysis of radioactivity. The RadNet network, which has stations in each State,...

  20. Promotion of Homologous Recombination and Genomic Stability byRAD51AP1 via RAD51 Recombinase Enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Wiese, Claudia; Dray, Eloise; Groesser, Torsten; San Filippo,Joseph; Shi, Idina; Collins, David W.; Tsai, Miaw-Sheue; Williams,Gareth; Rydberg, Bjorn; Sung, Patrick; Schild, David

    2007-04-11

    Homologous recombination (HR) repairs chromosome damage and is indispensable for tumor suppression in humans. RAD51 mediates the DNA strand pairing step in HR. RAD51AP1 (RAD51 Associated Protein 1) is a RAD51-interacting protein whose function has remained elusive. Knockdown of RAD51AP1 in human cells by RNA interference engenders sensitivity to different types of genotoxic stress. Moreover, RAD51AP1-depleted cells are impaired for the recombinational repair of a DNA double-strand break and exhibit chromatid breaks both spontaneously and upon DNA damaging treatment. Purified RAD51AP1 binds dsDNA and RAD51, and it greatly stimulates the RAD51-mediated D-loop reaction. Biochemical and cytological results show that RAD51AP1 functions at a step subsequent to the assembly of the RAD51-ssDNA nucleoprotein filament. Our findings provide the first evidence that RAD51AP1 helps maintain genomic integrity via RAD51 recombinase enhancement.

  1. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... transducer sends out high-frequency sound waves (that the human ear cannot hear) into the body and then ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of Pelvic Ultrasound Imaging? Ultrasound waves are ...

  2. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z Ultrasound - Pelvis Ultrasound imaging of the pelvis uses sound waves to produce pictures of the structures and organs in the lower abdomen and pelvis. There are three types of pelvic ultrasound: abdominal, ...

  3. Carotid Ultrasound

    Science.gov (United States)

    ... this page from the NHLBI on Twitter. Carotid Ultrasound Also known as carotid duplex. Carotid ultrasound is a painless imaging test that uses high- ... of your carotid arteries. This test uses an ultrasound machine, which includes a computer, a screen, and ...

  4. Prostate Ultrasound

    Medline Plus

    Full Text Available ... other imaging methods. Ultrasound imaging uses no ionizing radiation. Ultrasound scanning may be able to give a clearer picture of soft tissues that do not show up well on x-ray images. Ultrasound causes no health problems and may be repeated as often as ...

  5. Express Testing Makes for More Effective Vet Visit

    Science.gov (United States)

    2003-01-01

    This paper presents a discussion on Vetscan, a system designed to provide veterinarians with instant diagnostic information needed for rapid treatment decisions. VetScan is designed for point-of-care testing in any treatment setting, including mobile environments, where veterinarians can operate the analyzer from a car-lighter adapter. A full range of tests is available for almost every species normally treated by veterinarians, including cats, dogs, birds, reptiles, and large animals, such as those in the equine and bovine families.

  6. LBNL report of the vetting review of the GRETINA project

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, K.E.; Bercovitz, J.H.; Bieser, F.S.; Jared, R.C.; Karpenko, V.P.; Klein, S.R.; Lesko, K.T.; Rasson, J.E.; Ritter, H.G.; Tull, C.E.; Wells, R.; Wieman, H.H.

    2004-03-29

    GRETINA is a gamma-ray detector array capable of reconstructing the energy and spatial positions of gamma-ray interactions within the germanium crystals. It will be used to study the structure and stability of nuclei under various conditions. The new capabilities provided by gamma-ray tracking will give large gains in sensitivity for a large number of experiments, particularly those aimed at nuclei far from beta stability. A proposal for GRETINA was submitted to DOE in June 2003. It presented the scientific case, the readiness of technical development, the design, the suggested management organizations, and a proposed cost and schedule. The GRETINA proposal received its CD0 approval in August 2003. The CD-1 review will be held on December 3 and 4, 2003, and will be handled by the DOE-N. This report presents the charge to the GRETINA vetting review committee, and the findings, comments and recommendations of this committee. The purpose of this project vetting review was to assure that the GRETINA project is on track to provide DOE and the nuclear physics community with the agreed upon deliverables within the agreed upon budget and schedule. The vetting review committee was asked to cover both technical and management aspects of the GRETINA Project. Reviewers offer expert knowledge in relevant areas and provide recommendations and findings to the project's management team. Upon successful completion, the Laboratory's Integrated Project Management Office (IPMO) will recommend signoff of the project to the Laboratory Directorate. The GRETINA vetting review committee was asked to consider all relevant aspects of the project's management, project execution plan (PEP), technical approach and status, cost estimate, resources, schedule and risk and, in doing so, to advise as to whether the GRETINA Project was likely to successfully provide the agreed upon deliverables within the agreed upon budget and schedule. The review committee was asked to identify any

  7. RadTown USA Neighborhoods | US EPA

    Science.gov (United States)

    2016-09-08

    Learn about radiation sources and uses in the interactive, virtual community of RadTown USA! Explore radiation sources and uses in homes and schools, medical buildings and laboratories and outdoors. You will also find information about coal-fired power plants and nuclear power plants, power lines and learn about responding to radiation emergencies.

  8. RAD51B in Familial Breast Cancer

    DEFF Research Database (Denmark)

    Pelttari, Liisa M; Khan, Sofia; Vuorela, Mikko

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition......, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD......51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC) that were genotyped on a custom chip (iCOGS). We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients...

  9. HiRadMat: materials under scrutiny

    CERN Multimedia

    Anaïs Schaeffer

    2011-01-01

    CERN's new facility, HiRadMat (High Radiation to Materials), which is designed to test materials for the world's future particle accelerators, should be operational and welcoming its first experiments by the end of the year.   The HiRadMat facility, located in the TNC tunnel. The materials used in the LHC and its experiments are exposed to very high-energy particles. The LHC machine experts obviously didn't wait for the first collisions in the world's most powerful accelerator to put the materials through their paces - the equipment was validated following a series of stringent tests. And these tests will get even tougher now, with the arrival of HiRadMat. The tunnel that formerly housed the West Area Neutrino Facility (WANF) has been completely revamped to make way for CERN's latest facility, HiRadMat. Supported by the Radioprotection service, a team from the Engineering (EN) Department handled the dismantling operations from October 2009 to December 2010. "We could only work on disman...

  10. Inter-subunit interactions that coordinate Rad51's activities

    NARCIS (Netherlands)

    A.A. Grigorescu (Arabela); J.H.A. Vissers (Joseph); D. Ristic (Dejan); Y.Z. Pigli (Ying); T.W. Lynch (Thomas); C. Wyman (Claire); P.A. Rice (Phoebe)

    2009-01-01

    textabstractRad51 is the central catalyst of homologous recombination in eukaryotes and is thus critical for maintaining genomic integrity. Recent crystal structures of filaments formed by Rad51 and the closely related archeal RadA and eubacterial RecA proteins place the ATPase site at the

  11. CLSI performance standards for antimicrobial susceptibility testing of bacteria isoloated from aquatic animals; second information supplement. CLSI document VET03/VET04-S2

    Science.gov (United States)

    The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI) approved documents VET03-A Methods for Antimicrobial Disk Susceptibility Testing of Bacte...

  12. Renaissance or a Backward Step? Disparities and Tensions in Two New Swedish Pathways in VET

    Science.gov (United States)

    Berglund, Ingrid; Loeb, Ingrid Henning

    2013-01-01

    This article builds on results from studies of two new pathways in Swedish upper secondary VET. A major reform was launched in 2011 and the restructuring was presented by the Minister of Education as a "renaissance for VET education". The conclusion of the Upper Secondary Commission is that "students shall be more specialised within…

  13. Governance in English VET: On the Functioning of a Fractured "System"

    Science.gov (United States)

    Keep, Ewart

    2015-01-01

    This article explores the governance structures that cover vocational education and training (VET) in England. The English VET system is highly fragmented, complex and unstable, and has tended to oscillate between centralised command and control, and attempts at marketisation. Its governance arrangements reflect this situation. The various…

  14. Agenda-Setting for VET Policy in the Western Balkans: Employability versus Social Inclusion

    Science.gov (United States)

    Bartlett, Will; Pagliarello, Marina Cino

    2016-01-01

    For the last decade, the Western Balkan countries have sought to modernise their vocational education and training (VET) systems, adapting them to the needs of their emerging market economies. Within the framework of the EU accession process, the policy agenda for VET policies has been strongly influenced by a range of international and domestic…

  15. Does Scored VET in Schools Help or Hinder Access to Higher Education in Victoria?

    Science.gov (United States)

    Polidano, Cain; Tabasso, Domenico; Zhang, Rong

    2014-01-01

    Despite comprising only a small fraction of all vocational education and training (VET) in Schools enrolments, programs that count towards both national VET qualifications and university entry potentially fill an important role in the upper-secondary school curriculum. The aim of this study is to take a first step in gaining an understanding of…

  16. 41 CFR Appendix A to Part 61 - 300-Federal Contractor Veterans' Employment Report VETS-100A

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 300-Federal Contractor Veterans' Employment Report VETS-100A A Appendix A to Part 61 Public Contracts and Property Management.... A Appendix A to Part 61-300—Federal Contractor Veterans' Employment Report VETS-100A ER19MY08.024...

  17. The Contribution of VET Student Placement to Innovation in Host Organisations--Support Document

    Science.gov (United States)

    Hodge, Steven; Smith, Raymond; Field, Jenny; Flynn, Matthew

    2017-01-01

    This document gathers material used in the research project entitled: "The Contribution of VET Student Placement to Innovation in Host Organisations" that was not presented in the main report. The project sought to explore the question, "What is the contribution of the VET student placement process to innovation in host…

  18. The Role of VET in the (Dis)placing of Migrants' Skills in Australia

    Science.gov (United States)

    Webb, Sue; Faine, Miriam; Pardy, John; Roy, Reshmi

    2017-01-01

    Vocational Education and Training (VET) in a policy and institutional sense plays an important role in the migration experiences of people who settle in Australia. This article draws on qualitative empirical work using narrative accounts from VET practitioners along with a cross section of ethnically diverse migrants to reveal how race and…

  19. Access to the Albanian VET System: Social, Individual and School-Based Barriers

    Science.gov (United States)

    Xhumari, Merita; Dibra, Sidita

    2016-01-01

    This article analyses the determinants of access to the VET system in Albania and its impact on the inclusion of young people and vulnerable groups. The VET system often attracts students who have completed the compulsory levels of education with weak academic results. Many come from families with a low level of income and a low education level.…

  20. 41 CFR Appendix A to Part 61 - 250-Federal Contractor Veterans' Employment Report VETS-100

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 250-Federal Contractor Veterans' Employment Report VETS-100 A Appendix A to Part 61 Public Contracts and Property Management Other... Appendix A to Part 61-250—Federal Contractor Veterans' Employment Report VETS-100 ER05NO08.000 ER05NO08.001...

  1. A Curriculum Tailored for Workers? Knowledge Organization and Possible Transitions in Swedish VET

    Science.gov (United States)

    Nylund, Mattias; Rosvall, Per-Åke

    2016-01-01

    A key feature of the Swedish upper secondary school reform of 2011 (GY11) is the new direction it sets out for the organization of vocational education (VET) and the role it plays in youths' transitions from school to work. This study analyses the GY11 reform in terms of its impact on the organization of knowledge in VET and its implications for…

  2. Supporting teachers and trainers for successful reforms and quality of VET

    DEFF Research Database (Denmark)

    Kruse, Katrine; Gottlieb, Susanne; Andersen, Ole Dibbern

    This article presents how teachers and trainers in the Danish vocational education and training (VET) system are prepared for their work as professionals in an educational system undergoing rapid changes.......This article presents how teachers and trainers in the Danish vocational education and training (VET) system are prepared for their work as professionals in an educational system undergoing rapid changes....

  3. VET Workers' Problem-Solving Skills in Technology-Rich Environments: European Approach

    Science.gov (United States)

    Hämäläinen, Raija; Cincinnato, Sebastiano; Malin, Antero; De Wever, Bram

    2014-01-01

    The European workplace is challenging VET adults' problem-solving skills in technology-rich environments (TREs). So far, no international large-scale assessment data has been available for VET. The PIAAC data comprise the most comprehensive source of information on adults' skills to date. The present study (N = 50 369) focuses on gaining insight…

  4. Never a dull day as a vet working in public health.

    Science.gov (United States)

    Aldiss, Jason

    2016-03-12

    Jason Aldiss entered vet school in New Zealand knowing that he didn't want to go into general practice. Despite that, after qualifying he did spend two years in large animal practice. Having taken a keen interest in the role vets can play in society, he came to the UK to become an Official Veterinarian. British Veterinary Association.

  5. Promoting "Learner Voice" in VET: Developing Democratic, Transformative Possibilities or Further Entrenching the Status Quo?

    Science.gov (United States)

    Angus, Lawrence; Golding, Barry; Foley, Annette; Lavender, Peter

    2013-01-01

    In order to critique the notion of "learner voice" in vocational education and training (VET) policy, this paper draws from a project conducted by the authors on behalf of the Australian National VET Equity Advisory Council (NVEAC). The term "learner voice" is used extensively throughout NVEAC documentation to describe the…

  6. Being a vet is so much more than working with animals.

    Science.gov (United States)

    Little, Annika

    2014-11-08

    Annika Little is a student at Glasgow vet school. Earlier this year she discovered that lambing is a fulfilling EMS experience; however, it was the family who welcomed her into their home that made her realise that being a vet is about working with people. British Veterinary Association.

  7. A Preliminary Analysis of the Outcomes of Students Assisted by VET FEE-HELP

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2015

    2015-01-01

    VET FEE-HELP is an income-contingent loan scheme that assists eligible students undertaking certain vocational education and training (VET) courses (diploma, advanced diploma, graduate certificate and graduate diploma) with an approved provider by paying for all or part of their tuition costs. The tuition costs are paid directly to the provider.…

  8. The role of VET Colleges in stimulating teachers’ engagement in team learning

    NARCIS (Netherlands)

    Bouwmans, Machiel

    2018-01-01

    The necessity of VET teachers’ engagement in team learning Secondary vocational education and training, here abbreviated as VET, has a central position in the Dutch education system. It is the second largest education sector and qualifies large numbers of students for many

  9. Youth Transitions, VET and the "Making" of Class: Changing Theorisations for Changing Times?

    Science.gov (United States)

    Avis, James; Atkins, Liz

    2017-01-01

    The paper places youth transitions and vocational education and training (VET) within the global policy context in which economic competiveness is hegemonic. It compares research from the 1970s/80s, which explored young peoples' lived experiences of VET and youth training schemes with contemporary work on similar themes. It argues that there are…

  10. Virtual Voices with Real-Life Consequences: Teaching Students about Cyber-Vetting

    Science.gov (United States)

    Hanasono, Lisa Kiyomi

    2013-01-01

    Despite its pervasiveness, many students do not realize how online communication can impact their careers and relationships. Cyber-vetting occurs when people use online search engines, social networking sites, and other Internet tools to uncover information about others. Because cyber-vetting is a relatively new concept, most communication…

  11. Analysis list: RAD21 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ncedbc.jp/kyushu-u/hg19/target/RAD21.1.tsv http://dbarchive.biosciencedbc.jp/kyushu...-u/hg19/target/RAD21.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/RAD21.10.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/hg19/colo/RAD21.Blood.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/hg19/colo/RAD21.Breast.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/RAD21.Dige...stive_tract.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/RAD21.Liver.tsv,http://dbarchive.bioscience

  12. Analysis list: Rad21 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ,Spleen + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Rad21.1.tsv http://dbarchive.bioscienced...bc.jp/kyushu-u/mm9/target/Rad21.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Rad21.10.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Rad21.Blood.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Rad21.Digestive_tract.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9.../colo/Rad21.Embryonic_fibroblast.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Rad21.Liver.tsv,http://dbarchive.bioscience

  13. RAD51B in Familial Breast Cancer.

    Directory of Open Access Journals (Sweden)

    Liisa M Pelttari

    Full Text Available Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC that were genotyped on a custom chip (iCOGS. We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients and subsequently genotyped the mutation in additional breast cancer cases (n = 5259 and population controls (n = 3586 from Finland and Belarus. No significant association with breast cancer risk was seen in the meta-analysis of the Finnish datasets or in the large BCAC dataset. The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR: 1.15, 95% confidence interval (CI: 1.11-1.19, P = 8.88 x 10-16 and among familial cases (OR: 1.24, 95% CI: 1.16-1.32, P = 6.19 x 10-11, compared to the haplotype with the respective protective alleles. Our results suggest that loss-of-function mutations in RAD51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk.

  14. RAD51B in Familial Breast Cancer

    Science.gov (United States)

    Pelttari, Liisa M.; Khan, Sofia; Vuorela, Mikko; Kiiski, Johanna I.; Vilske, Sara; Nevanlinna, Viivi; Ranta, Salla; Schleutker, Johanna; Winqvist, Robert; Kallioniemi, Anne; Dörk, Thilo; Bogdanova, Natalia V.; Figueroa, Jonine; Pharoah, Paul D. P.; Schmidt, Marjanka K.; Dunning, Alison M.; García-Closas, Montserrat; Bolla, Manjeet K.; Dennis, Joe; Michailidou, Kyriaki; Wang, Qin; Hopper, John L.; Southey, Melissa C.; Rosenberg, Efraim H.; Fasching, Peter A.; Beckmann, Matthias W.; Peto, Julian; dos-Santos-Silva, Isabel; Sawyer, Elinor J.; Tomlinson, Ian; Burwinkel, Barbara; Surowy, Harald; Guénel, Pascal; Truong, Thérèse; Bojesen, Stig E.; Nordestgaard, Børge G.; Benitez, Javier; González-Neira, Anna; Neuhausen, Susan L.; Anton-Culver, Hoda; Brenner, Hermann; Arndt, Volker; Meindl, Alfons; Schmutzler, Rita K.; Brauch, Hiltrud; Brüning, Thomas; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; Hartikainen, Jaana M.; Chenevix-Trench, Georgia; Van Dyck, Laurien; Janssen, Hilde; Chang-Claude, Jenny; Rudolph, Anja; Radice, Paolo; Peterlongo, Paolo; Hallberg, Emily; Olson, Janet E.; Giles, Graham G.; Milne, Roger L.; Haiman, Christopher A.; Schumacher, Fredrick; Simard, Jacques; Dumont, Martine; Kristensen, Vessela; Borresen-Dale, Anne-Lise; Zheng, Wei; Beeghly-Fadiel, Alicia; Grip, Mervi; Andrulis, Irene L.; Glendon, Gord; Devilee, Peter; Seynaeve, Caroline; Hooning, Maartje J.; Collée, Margriet; Cox, Angela; Cross, Simon S.; Shah, Mitul; Luben, Robert N.; Hamann, Ute; Torres, Diana; Jakubowska, Anna; Lubinski, Jan; Couch, Fergus J.; Yannoukakos, Drakoulis; Orr, Nick; Swerdlow, Anthony; Darabi, Hatef; Li, Jingmei; Czene, Kamila; Hall, Per; Easton, Douglas F.; Mattson, Johanna; Blomqvist, Carl; Aittomäki, Kristiina; Nevanlinna, Heli

    2016-01-01

    Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC) that were genotyped on a custom chip (iCOGS). We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients and subsequently genotyped the mutation in additional breast cancer cases (n = 5259) and population controls (n = 3586) from Finland and Belarus. No significant association with breast cancer risk was seen in the meta-analysis of the Finnish datasets or in the large BCAC dataset. The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR): 1.15, 95% confidence interval (CI): 1.11–1.19, P = 8.88 x 10−16) and among familial cases (OR: 1.24, 95% CI: 1.16–1.32, P = 6.19 x 10−11), compared to the haplotype with the respective protective alleles. Our results suggest that loss-of-function mutations in RAD51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk. PMID:27149063

  15. Standards for MRI reporting-the evolution to PI-RADS v 2.0.

    Science.gov (United States)

    Spektor, Michael; Mathur, Mahan; Weinreb, Jeffrey C

    2017-06-01

    Prostate cancer (PCa) remains a leading cause of death in the United States, but the vast majority of men diagnosed with PCa will die from other causes. While historically the capability of assessing the risk of life-threatening versus indolent PCa has relied heavily on serum prostate-specific antigen (PSA) and transrectal ultrasound (TRUS), multiparametric magnetic resonance imaging (mpMRI) has emerged as the leading tool for detection and characterization of clinically significant PCa. However, wide variations and lack of standardization of mpMRI data acquisition, interpretation, and reporting have hampered its progress. The development of a set of consensus guidelines, initially called Prostate Imaging and Reporting and Data System (PI-RADS) and eventually updated to a document called PI-RADS v2 has attempted to solve these shortcomings. As it stands, PI-RADS v2 currently represents the most up-to-date information on how to acquire, interpret, and report mpMRI of the prostate.

  16. Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

    Science.gov (United States)

    Song, Honglin; Dicks, Ed; Ramus, Susan J.; Tyrer, Jonathan P.; Intermaggio, Maria P.; Hayward, Jane; Edlund, Christopher K.; Conti, David; Harrington, Patricia; Fraser, Lindsay; Philpott, Susan; Anderson, Christopher; Rosenthal, Adam; Gentry-Maharaj, Aleksandra; Bowtell, David D.; Alsop, Kathryn; Cicek, Mine S.; Cunningham, Julie M.; Fridley, Brooke L.; Alsop, Jennifer; Jimenez-Linan, Mercedes; Høgdall, Estrid; Høgdall, Claus K.; Jensen, Allan; Kjaer, Susanne Krüger; Lubiński, Jan; Huzarski, Tomasz; Jakubowska, Anna; Gronwald, Jacek; Poblete, Samantha; Lele, Shashi; Sucheston-Campbell, Lara; Moysich, Kirsten B.; Odunsi, Kunle; Goode, Ellen L.; Menon, Usha; Jacobs, Ian J.; Gayther, Simon A.; Pharoah, Paul D.P.

    2015-01-01

    Purpose The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the population and in a screening trial of individuals at high risk of ovarian cancer. Patients and Methods The coding sequence and splice site boundaries of the three RAD51 genes were sequenced and analyzed in germline DNA from a case-control study of 3,429 patients with invasive EOC and 2,772 controls as well as in 2,000 unaffected women who were BRCA1/BRCA2 negative from the United Kingdom Familial Ovarian Cancer Screening Study (UK_FOCSS) after quality-control analysis. Results In the case-control study, we identified predicted deleterious mutations in 28 EOC cases (0.82%) compared with three controls (0.11%; P < .001). Mutations in EOC cases were more frequent in RAD51C (14 occurrences, 0.41%) and RAD51D (12 occurrences, 0.35%) than in RAD51B (two occurrences, 0.06%). RAD51C mutations were associated with an odds ratio of 5.2 (95% CI, 1.1 to 24; P = .035), and RAD51D mutations conferred an odds ratio of 12 (95% CI, 1.5 to 90; P = .019). We identified 13 RAD51 mutations (0.65%) in unaffected UK_FOCSS participants (RAD51C, n = 7; RAD51D, n = 5; and RAD51B, n = 1), which was a significantly greater rate than in controls (P < .001); furthermore, RAD51 mutation carriers were more likely than noncarriers to have a family history of ovarian cancer (P < .001). Conclusion These results confirm that RAD51C and RAD51D are moderate ovarian cancer susceptibility genes and suggest that they confer levels of risk of EOC that may warrant their use alongside BRCA1 and BRCA2 in routine clinical genetic testing. PMID:26261251

  17. Context and Capabilities: Tensions between Managers' and Teachers' Views of Advanced Skills in VET

    Science.gov (United States)

    Schmidt, Teressa

    2017-01-01

    The concept of "advanced skills" for vocational education and training (VET) teachers is a little-debated topic in the discourse about quality in Australian VET, yet arguably what makes for a "good" VET teacher ought to be a prominent issue. There has however, been some sporadic interest in the topic with Mitchell, in…

  18. 20 CFR 1002.303 - Is an individual required to file his or her complaint with VETS?

    Science.gov (United States)

    2010-04-01

    ... complaint with VETS? 1002.303 Section 1002.303 Employees' Benefits OFFICE OF THE ASSISTANT SECRETARY FOR... or her complaint with VETS? No. The individual may initiate a private action for relief against a State or private employer if he or she decides not to apply to VETS for assistance. ...

  19. Application of Prostate Imaging Reporting and Data System Version 2 (PI-RADS v2): Interobserver Agreement and Positive Predictive Value for Localization of Intermediate- and High-Grade Prostate Cancers on Multiparametric Magnetic Resonance Imaging.

    Science.gov (United States)

    Chen, Frank; Cen, Steven; Palmer, Suzanne

    2017-09-01

    To evaluate interobserver agreement with the use of and the positive predictive value (PPV) of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) for the localization of intermediate- and high-grade prostate cancers on multiparametric magnetic resonance imaging (mpMRI). In this retrospective, institutional review board-approved study, 131 consecutive patients who had mpMRI followed by transrectal ultrasound-MR imaging fusion-guided biopsy of the prostate were included. Two readers who were blinded to initial mpMRI reports, clinical data, and pathologic outcomes reviewed the MR images, identified all prostate lesions, and scored each lesion based on the PI-RADS v2. Interobserver agreement was assessed by intraclass correlation coefficient (ICC), and PPV was calculated for each PI-RADS category. PI-RADS v2 was found to have a moderate level of interobserver agreement between two readers of varying experience, with ICC of 0.74, 0.72, and 0.67 for all lesions, peripheral zone lesions, and transitional zone lesions, respectively. Despite only moderate interobserver agreement, the calculated PPV in the detection of intermediate- and high-grade prostate cancers for each PI-RADS category was very similar between the two readers, with approximate PPV of 0%, 12%, 64%, and 87% for PI-RADS categories 2, 3, 4, and 5, respectively. In our study, PI-RADS v2 has only moderate interobserver agreement, a similar finding in studies of the original PI-RADS and in initial studies of PI-RADS v2. Despite this, PI-RADS v2 appears to be a useful system to predict significant prostate cancer, with PI-RADS scores correlating well with the likelihood of intermediate- and high-grade cancers. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  20. Breast ultrasound scans – surgeons’ expectations

    Directory of Open Access Journals (Sweden)

    Piotr Bednarski

    2015-06-01

    Full Text Available Recent years have witnessed a dynamic development of mammary gland imaging techniques, particularly ultrasonography and magnetic resonance imaging. A challenge related to these studies is the increase in the precision of the anatomical assessment of breast, particularly for early detection of subclinical lesions, performance of ultrasound-guided biopsy procedures, and accurate preoperative location of pathological lesions so as to optimize the surgical treatment. Ultrasound imaging is a primary and baseline diagnostic procedure the patient with suspected pathological lesions within breast is referred to by the surgeon. Lesions visualized in ultrasound scans are classifi ed according to the BI-RADS US assessment categories. The successive categories (2 through 6 encompass individual pathological lesions, estimating the risk of malignancy and provide guidelines for further diagnostic and therapeutic management. This article described the important aspects of ultrasonographic imaging of focal lesions within the breasts as signifi cant from the standpoint of surgical treatment of patients falling within BI-RADS US categories 3, 4, 5, and 6. Attention is drawn to the importance of ultrasound scans in the assessment of axillary fossa lymph nodes before the decision regarding the surgical treatment.

  1. Nuclear localization of Rad51B is independent of BRCA2

    Energy Technology Data Exchange (ETDEWEB)

    Miller, K A; Hinz, J M; Yamada, A; Thompson, L H; Albala, J S

    2005-06-28

    Human Rad51 is critical for the maintenance of genome stability through its role in the repair of DNA double-strand breaks. Rad51B (Rad51L1/hRec2) is one of the five known paralogs of human Rad51 found in a multi-protein complex with three other Rad51 paralogs, Rad51C, Rad51D and Xrcc2. Examination of EGFP-Rad51B fusion protein in HeLa S3 cells and immunofluorescence in several human cell lines confirms the nuclear localization of Rad51B. This is the first report to detail putative interactions of a Rad51 paralog protein with BRCA2. Utilization of a BRCA2 mutant cell line, CAPAN-1 suggests that Rad51B localizes to the nucleus independent of BRCA2. Although both Rad51B and BRCA2 are clearly involved in the homologous recombinational repair pathway, Rad51B and BRCA2 do not appear to associate directly. Furthermore, mutations in the KKLK motif of Rad51B, amino acid residues 4-7, mislocalizes Rad51B to the cytoplasm suggesting that this is the nuclear localization signal for the Rad51B protein. Examination of wild-type EGFP-Rad51B fusion protein in mammalian cells deficient in Rad51C showed that Rad51B localizes to the nucleus independent of Rad51C; further suggesting that Rad51B, like Rad51C, contains its own nuclear localization signal.

  2. Bringing Rad52 foci into focus

    Science.gov (United States)

    Alvaro, David; Lisby, Michael

    2011-01-01

    In 2007, we published the results of a genome-wide screen for ORFs that affect the frequency of Rad52 foci in yeast. That paper was published within the constraints of conventional online publishing tools, and it provided only a glimpse into the actual screen data. New tools in the JCB DataViewer now show how these data can—and should—be shared. PMID:21893595

  3. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... internal organs, as well as blood flowing through blood vessels. Ultrasound imaging is a noninvasive medical test that helps physicians diagnose and treat medical conditions. ...

  4. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z General Ultrasound Ultrasound imaging uses sound waves to produce pictures ... limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and painless, and produces ...

  5. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... inserted into a man's rectum to view the prostate. Transvaginal ultrasound. The transducer is inserted into a ... Stenting Ultrasound-Guided Breast Biopsy Obstetric Ultrasound Ultrasound - Prostate Biopsies - Overview Images related to General Ultrasound Videos ...

  6. Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart.

    Science.gov (United States)

    Levitan, Bryana M; Manning, Janet R; Withers, Catherine N; Smith, Jeffrey D; Shaw, Robin M; Andres, Douglas A; Sorrell, Vincent L; Satin, Jonathan

    2016-12-01

    Sympathetic stimulation modulates L-type calcium channel (LTCC) gating to contribute to increased systolic heart function. Rad is a monomeric G-protein that interacts with LTCC. Genetic deletion of Rad (Rad(-/-)) renders LTCC in a sympathomimetic state. The study goal was to use a clinically inspired pharmacological stress echocardiography test, including analysis of global strain, to determine whether Rad(-/-) confers tonic positive inotropic heart function. Sarcomere dynamics and strain showed partial parallel isoproterenol (ISO) responsiveness for wild-type (WT) and for Rad(-/-). Rad(-/-) basal inotropy was elevated compared to WT but was less responsiveness to ISO. Rad protein levels were lower in human patients with end-stage non-ischemic heart failure. These results show that Rad reduction provides a stable inotropic response rooted in sarcomere level function. Thus, reduced Rad levels in heart failure patients may be a compensatory response to need for increased output in the setting of HF. Rad deletion suggests a future therapeutic direction for inotropic support.

  7. Targeted MRI/TRUS fusion-guided biopsy in men with previous prostate biopsies using a novel registration software and multiparametric MRI PI-RADS scores: first results.

    Science.gov (United States)

    Tewes, Susanne; Hueper, Katja; Hartung, Dagmar; Imkamp, Florian; Herrmann, Thomas R W; Weidemann, Juergen; Renckly, Stefan; Kuczyk, Markus A; Wacker, Frank; Peters, Inga

    2015-11-01

    To evaluate a novel system for MRI/TRUS fusion-guided biopsy for detection of prostate cancer (PCa) in patients with previous negative prostate biopsy and determine diagnostic accuracy when using the Prostate Imaging Reporting and Data System (PI-RADS) for multiparametric magnetic resonance imaging (mpMRI) as proposed by the European Society of Urogenital Radiology. Thirty-nine men with clinical suspicion of PCa and history of previous prostate biopsy underwent mpMRI on a 3-T MRI. In total, 72 lesions were evaluated by the consensus of two radiologists. PI-RADS scores for each MRI sequence, the sum of the PI-RADS scores and the global PI-RADS were determined. MRI/TRUS fusion-guided targeted biopsy was performed using the BioJet™ software combined with a transrectal ultrasound system. Image fusion was based on rigid registration. PI-RADS scores of the dominant lesion were compared with histopathological results. Diagnostic accuracy was determined using receiver operating characteristic curve analysis. MRI/TRUS fusion-guided biopsy was reliable and successful for 71 out of 72 lesions. The global PI-RADS score of the dominant lesion was significantly higher in patients with PCa (4.0 ± 1.3) compared to patients with negative histopathology (2.6 ± 0.8; p = 0.0006). Using a global PI-RADS score cut-off ≥4, a sensitivity of 85 %, a specificity of 82 % and a negative predictive value of 92 % were achieved. The described fusion system is dependable and efficient for targeted MRI/TRUS fusion-guided biopsy. mpMRI PI-RADS scores combined with a novel real-time MRI/TRUS fusion system facilitate sufficient diagnosis of PCa with high sensitivity and specificity.

  8. Question vetting: the process to ensure quality in assessment of medical students.

    Science.gov (United States)

    Gopalakrishnan, S; Udayshankar, P M

    2014-09-01

    Over the past decade, medical schools have made new efforts to provide accurate, reliable, and timely assessments of the competence of trainees. All methods of assessment have strengths and intrinsic flaws. Written examination questions forms an important item in knowledge assessment and are typically classified according to whether they are open-ended or multiple choices. At present questions are prepared casually just before the examination and are not put through any quality check to correct any possible mistakes or ambiguity in the questions. This may lead to confusion or wrong understanding of the questions by the students which will be reflected in their answers as well. Question Vetting is the process when an expert person examines or evaluates and edits questions to make it free of any mistakes. The importance of vetting and re-vetting of examination questions cannot be overstated in the present scenario of medical education. There is a prescribed structure and protocol of question setting and vetting for examinations in medical education programmes. The areas that need to be examined during question vetting are for technical accuracy, content level and language aspects. The use of the prescribed structure and protocol of question vetting ensures a consistently high standard of question presentation during examinations which will help the students to understand the questions better and to answer them correctly. This article is intended to highlight the importance of introducing question vetting in our medical education scenario in order to improve the quality of assessment of medical students.

  9. VET workers’ problem-solving skills in technology-rich environments: European approach

    Directory of Open Access Journals (Sweden)

    Raija Hämäläinen

    2014-08-01

    Full Text Available The European workplace is challenging VET adults’ problem-solving skills in technology-rich environments (TREs. So far, no international large-scale assessment data has been available for VET. The PIAAC data comprise the most comprehensive source of information on adults’ skills to date. The present study (N=50 369 focuses on gaining insight into the problem-solving skills in TREs of adults with a VET background. When examining the similarities and differences in VET adults’ problem-solving skills in TREs across 11 European countries, two main trends can be observed. First, our results show that only a minority of VET adults perform at a high level. Second, there seems to be substantial variation between countries with respect to the proportion of VET adults that can be identified as “at-risk” or “weak” performers. For the future, our findings indicate the variations that can be used as a starting point to identify beneficial VET approaches.

  10. Accuracy and reproducibility of the TonoVet rebound tonometer in birds of prey.

    Science.gov (United States)

    Reuter, Anne; Müller, Kerstin; Arndt, Gisela; Eule, Johanna Corinna

    2010-09-01

    To examine the accuracy and reproducibility of intraocular pressure (IOP) measurements obtained by the TonoVet rebound tonometer. Animals studied  Freshly enucleated healthy eyes of 44 free-ranging birds of prey out of the species Haliaeetus albicilla, Accipiter gentilis, Accipiter nisus, Buteo buteo, Falco tinnunculus, Strix aluco, Asio otus and Tyto alba euthanized because of unrelated health problems. IOP readings from the TonoVet were compared with a manometric device, with IOP being set from 5 to 100 mmHg in steps of 5 mmHg by adjusting the height of a NaCl solution reservoir connected to the eye. Reproducibility of the TonoVet readings was determined by repeated measurements. TonoVet and manometer values showed a strong linear correlation. In the Accipitridae, the TonoVet tended to increasingly overestimate IOP with increasing pressure, while in the other families, it increasingly underestimated it. In the Sparrowhawk, the values almost represent the ideal line. Reproducibility of TonoVet values decreases with increasing pressure in the clinically important range from 5 to 60 mmHg. IOP values measured with the TonoVet demonstrated species specific deviation from the manometric measurements. These differences should be considered when interpreting IOP values. Using the regression formulae presented, corrected IOP values could be calculated in a clinical setting.

  11. Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2.

    Directory of Open Access Journals (Sweden)

    Aline Esta

    Full Text Available The budding yeast Srs2 is the archetype of helicases that regulate several aspects of homologous recombination (HR to maintain genomic stability. Srs2 inhibits HR at replication forks and prevents high frequencies of crossing-over. Additionally, sensitivity to DNA damage and synthetic lethality with replication and recombination mutants are phenotypes that can only be attributed to another role of Srs2: the elimination of lethal intermediates formed by recombination proteins. To shed light on these intermediates, we searched for mutations that bypass the requirement of Srs2 in DNA repair without affecting HR. Remarkably, we isolated rad52-L264P, a novel allele of RAD52, a gene that encodes one of the most central recombination proteins in yeast. This mutation suppresses a broad spectrum of srs2Δ phenotypes in haploid cells, such as UV and γ-ray sensitivities as well as synthetic lethality with replication and recombination mutants, while it does not significantly affect Rad52 functions in HR and DNA repair. Extensive analysis of the genetic interactions between rad52-L264P and srs2Δ shows that rad52-L264P bypasses the requirement for Srs2 specifically for the prevention of toxic Rad51 filaments. Conversely, this Rad52 mutant cannot restore viability of srs2Δ cells that accumulate intertwined recombination intermediates which are normally processed by Srs2 post-synaptic functions. The avoidance of toxic Rad51 filaments by Rad52-L264P can be explained by a modification of its Rad51 filament mediator activity, as indicated by Chromatin immunoprecipitation and biochemical analysis. Remarkably, sensitivity to DNA damage of srs2Δ cells can also be overcome by stimulating Rad52 sumoylation through overexpression of the sumo-ligase SIZ2, or by replacing Rad52 by a Rad52-SUMO fusion protein. We propose that, like the rad52-L264P mutation, sumoylation modifies Rad52 activity thereby changing the properties of Rad51 filaments. This conclusion is

  12. Regulation of Rad51-Mediated Homologous Recombination by BRCA2, DSS1 and RAD52

    DEFF Research Database (Denmark)

    Rants, Louise Olthaver Juhl

    Homologous recombination (HR) provides a mechanism to restore integrity and maintain stability of the genetic material. HR is a major pathway for repair of DNA double-strand breaks (DSB), recovery of broken replication forks and generation of meiotic crossovers. The defining step in HR...... in governing the activity of Rad51 and to learn how other recombination-associated proteins such as DSS1 and RAD52 contribute to its regulation. We use the yeast-like fungus Ustilago maydis and the avian DT40 cell line as experimental systems since both have a well-conserved BRCA2-based recombinational repair...

  13. Ultrasound -- Pelvis

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    Full Text Available ... body. Doppler ultrasound, a special application of ultrasound, measures the direction and speed of blood cells as they move through vessels. The movement of blood cells causes a change in pitch of the reflected sound waves (called the Doppler effect). A computer collects ...

  14. Ultrasound -- Pelvis

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    Full Text Available ... the body while other areas, especially air-filled lungs, are poorly suited for ultrasound. For ultrasound procedures requiring insertion of the transducer, such as transvaginal or transrectal exams, the device is covered with a sheath and lubricated before insertion. ...

  15. Prostate Ultrasound

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    Full Text Available ... the body while other areas, especially air-filled lungs, are poorly suited for ultrasound. For ultrasound procedures such as transrectal exams that require insertion of an imaging probe, also called a transducer, the device is covered and lubricated with a gel. top of ...

  16. Prostate Ultrasound

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    Full Text Available ... transducer sends out high-frequency sound waves (that the human ear cannot hear) into the body and then ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of Prostate Ultrasound Imaging? Men who have ...

  17. Ultrasound -- Pelvis

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    Full Text Available ... are some common uses of the procedure? In women, a pelvic ultrasound is most often performed to evaluate the: uterus cervix ovaries fallopian tubes bladder Pelvic ultrasound exams are also used to monitor the health and development of an embryo or fetus during ...

  18. Prostate Ultrasound

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    Full Text Available ... well on x-ray images. Ultrasound causes no health problems and may be repeated as often as is necessary if medically indicated. Ultrasound provides real-time imaging, making it a good tool for guiding minimally invasive procedures such as ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... areas of the body while other areas, especially air-filled lungs, are poorly suited for ultrasound. For ultrasound procedures requiring insertion of the transducer, such as transvaginal or transrectal exams, the device is covered with a sheath and lubricated before ...

  20. Prostate Ultrasound

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    Full Text Available ... areas of the body while other areas, especially air-filled lungs, are poorly suited for ultrasound. For ultrasound procedures such as transrectal exams that require insertion of an imaging probe, also called a transducer, the device is covered and lubricated with a gel. top ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... then uses those sound waves to create an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show ...

  2. Ultrasound - Scrotum

    Science.gov (United States)

    ... then uses those sound waves to create an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show ...

  3. Prostate Ultrasound

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    Full Text Available ... then uses those sound waves to create an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show ...

  4. Prostate Ultrasound

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    Full Text Available ... as needle biopsies and fluid aspiration. Risks For standard diagnostic ultrasound , there are no known harmful effects on humans. top of page What are the limitations of Prostate Ultrasound Imaging? Men who have had the tail end of their bowel ( ...

  5. Prostate Ultrasound

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    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Ultrasound - Prostate Ultrasound of ...

  6. Ultrasound -- Pelvis

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    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Ultrasound - Pelvis Ultrasound imaging ...

  7. Prostate Ultrasound

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    Full Text Available ... radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show the structure and movement of ... if a finding is stable or changed over time. top of page What are the benefits vs. risks? Benefits Ultrasound is widely ...

  8. Analysis list: Rad51 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Rad51 Blood,Gonad + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Rad51.1.tsv http:...//dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Rad51.5.tsv http://dbarchive.biosciencedbc.jp/k...yushu-u/mm9/target/Rad51.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Rad51.Blood.tsv,http://d...barchive.biosciencedbc.jp/kyushu-u/mm9/colo/Rad51.Gonad.tsv http://dbarchive.bios...ciencedbc.jp/kyushu-u/mm9/colo/Blood.gml,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Gonad.gml ...

  9. Sports Ultrasound

    Science.gov (United States)

    Finnoff, Jonathan T.; Ray, Jeremiah; Corrado, Gianmichael; Kerkhof, Deanna; Hill, John

    2016-01-01

    Background: Traditionally, ultrasound has been used to evaluate musculoskeletal injuries in athletes; however, ultrasound applications extend well beyond musculoskeletal conditions, many of which are pertinent to athletes. Evidence Acquisition: Articles were identified in PubMed using the search terms ultrasound, echocardiogram, preparticipation physical examination, glycogen, focused assessment with sonography of trauma, optic nerve, and vocal cord dysfunction. No date restrictions were placed on the literature search. Study Design: Clinical review. Level of Evidence: Level 4. Results: Several potential applications of nonmusculoskeletal ultrasound in sports medicine are presented, including extended Focused Assessment with Sonography for Trauma (eFAST), limited echocardiographic screening during preparticipation physical examinations, assessment of muscle glycogen stores, optic nerve sheath diameter measurements in athletes with increased intracranial pressure, and assessment of vocal cord dysfunction in athletes. Conclusion: Ultrasound can potentially be used to assist athletes with monitoring their muscle glycogen stores and the diagnosis of multiple nonmusculoskeletal conditions within sports medicine. PMID:27519599

  10. RadCat 2.0 User Guide.

    Energy Technology Data Exchange (ETDEWEB)

    Osborn, Douglas.; Weiner, Ruth F.; Mills, George Scott; Hamp, Steve C.; O' Donnell, Brandon, M.; Orcutt, David J.; Heames, Terence J.; Hinojosa, Daniel

    2005-01-01

    This document provides a detailed discussion and a guide for the use of the RadCat 2.0 Graphical User Interface input file generator for the RADTRAN 5.5 code. The differences between RadCat 2.0 and RadCat 1.0 can be attributed to the differences between RADTRAN 5 and RADTRAN 5.5 as well as clarification for some of the input parameters. 3

  11. Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing.

    Directory of Open Access Journals (Sweden)

    Nilesh V Khade

    Full Text Available Yeast Rad52 (yRad52 has two important functions at homologous DNA recombination (HR; annealing complementary single-strand DNA (ssDNA molecules and recruiting Rad51 recombinase onto ssDNA (recombination mediator activity. Its human homolog (hRAD52 has a lesser role in HR, and apparently lacks mediator activity. Here we show that yRad52 can load human Rad51 (hRAD51 onto ssDNA complexed with yeast RPA in vitro. This is biochemically equivalent to mediator activity because it depends on the C-terminal Rad51-binding region of yRad52 and on functional Rad52-RPA interaction. It has been reported that the N-terminal two thirds of both yRad52 and hRAD52 is essential for binding to and annealing ssDNA. Although a second DNA binding region has been found in the C-terminal region of yRad52, its role in ssDNA annealing is not clear. In this paper, we also show that the C-terminal region of yRad52, but not of hRAD52, is involved in ssDNA annealing. This suggests that the second DNA binding site is required for the efficient ssDNA annealing by yRad52. We propose an updated model of Rad52-mediated ssDNA annealing.

  12. Cranial Ultrasound/Head Ultrasound

    Science.gov (United States)

    ... then uses those sound waves to create an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show ...

  13. Inferring phylogenies from RAD sequence data.

    Directory of Open Access Journals (Sweden)

    Benjamin E R Rubin

    Full Text Available Reduced-representation genome sequencing represents a new source of data for systematics, and its potential utility in interspecific phylogeny reconstruction has not yet been explored. One approach that seems especially promising is the use of inexpensive short-read technologies (e.g., Illumina, SOLiD to sequence restriction-site associated DNA (RAD--the regions of the genome that flank the recognition sites of restriction enzymes. In this study, we simulated the collection of RAD sequences from sequenced genomes of different taxa (Drosophila, mammals, and yeasts and developed a proof-of-concept workflow to test whether informative data could be extracted and used to accurately reconstruct "known" phylogenies of species within each group. The workflow consists of three basic steps: first, sequences are clustered by similarity to estimate orthology; second, clusters are filtered by taxonomic coverage; and third, they are aligned and concatenated for "total evidence" phylogenetic analysis. We evaluated the performance of clustering and filtering parameters by comparing the resulting topologies with well-supported reference trees and we were able to identify conditions under which the reference tree was inferred with high support. For Drosophila, whole genome alignments allowed us to directly evaluate which parameters most consistently recovered orthologous sequences. For the parameter ranges explored, we recovered the best results at the low ends of sequence similarity and taxonomic representation of loci; these generated the largest supermatrices with the highest proportion of missing data. Applications of the method to mammals and yeasts were less successful, which we suggest may be due partly to their much deeper evolutionary divergence times compared to Drosophila (crown ages of approximately 100 and 300 versus 60 Mya, respectively. RAD sequences thus appear to hold promise for reconstructing phylogenetic relationships in younger clades in

  14. Rad51 activates polyomavirus JC early transcription.

    Directory of Open Access Journals (Sweden)

    Martyn K White

    Full Text Available The human neurotropic polyomavirus JC (JCV causes the fatal CNS demyelinating disease progressive multifocal leukoencephalopathy (PML. JCV infection is very common and after primary infection, the virus is able to persist in an asymptomatic state. Rarely, and usually only under conditions of immune impairment, JCV re-emerges to actively replicate in the astrocytes and oligodendrocytes of the brain causing PML. The regulatory events involved in the reactivation of active viral replication in PML are not well understood but previous studies have implicated the transcription factor NF-κB acting at a well-characterized site in the JCV noncoding control region (NCCR. NF-κB in turn is regulated in a number of ways including activation by cytokines such as TNF-α, interactions with other transcription factors and epigenetic events involving protein acetylation--all of which can regulate the transcriptional activity of JCV. Active JCV infection is marked by the occurrence of rapid and extensive DNA damage in the host cell and the induction of the expression of cellular proteins involved in DNA repair including Rad51, a major component of the homologous recombination-directed double-strand break DNA repair machinery. Here we show that increased Rad51 expression activates the JCV early promoter. This activation is co-operative with the stimulation caused by NF-κB p65, abrogated by mutation of the NF-κB binding site or siRNA to NFκB p65 and enhanced by the histone deacetylase inhibitor sodium butyrate. These data indicate that the induction of Rad51 resulting from infection with JCV acts through NF-κB via its binding site to stimulate JCV early transcription. We suggest that this provides a novel positive feedback mechanism to enhance viral gene expression during the early stage of JCV infection.

  15. Implementing Human Resources Management (HRM) within Dutch VET schools: Examining the fostering and hindering factors

    NARCIS (Netherlands)

    Runhaar, P.R.; Sanders, K.

    2013-01-01

    Vocational Education and Training (VET) Institutions face serious challenges, like the implementation of competence-based education and upcoming teacher shortages, which urge them to implement Human Resources Management policy and practices (HRM). The implementation of HRM, however, often stagnates.

  16. Ultrasound physics.

    Science.gov (United States)

    Shriki, Jesse

    2014-01-01

    Bedside ultrasound has become an important modality for obtaining critical information in the acute care of patients. It is important to understand the physics of ultrasound in order to perform and interpret images at the bedside. The physics of both continuous wave and pulsed wave sound underlies diagnostic ultrasound. The instrumentation, including transducers and image processing, is important in the acquisition of appropriate sonographic images. Understanding how these concepts interplay with each other enables practitioners to obtain the best possible images. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Retaining vets in farm animal practice: a cross-sectional study.

    Science.gov (United States)

    Adam, K; Baillie, S; Rushton, J

    2015-06-20

    Concerns have been raised about a potential shortage of farm animal vets in the UK. There is no apparent lack of new graduates willing to work with farm animals, but practices report difficulties in recruiting and retaining experienced farm animal vets. Retention of vets in farm animal practice has been identified as a key issue for the sustainability of veterinary businesses and livestock health. A cross-sectional study design was used to identify factors associated with vets remaining in farm animal practice. Data were collected via an online questionnaire covering employment, education, personal background and future plans. The target population was vets with experience of farm animal work in the UK. 380 responses were included in the analysis. Working in a practice where accommodation was provided and an increasing number of years since graduation were associated with significantly lower odds of remaining in farm animal practice, while working in a practice where staff appraisals were carried out; coming from a family with a commercial farm; spending more time on farm work and being on call with an experienced vet in the first job after graduation increased the odds of remaining in farm work. Gender was not significantly associated with retention. British Veterinary Association.

  18. Ultrasound -- Pelvis

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    Full Text Available ... various body organs such as the liver or kidneys. top of page What are some common uses ... women, a pelvic ultrasound exam can help identify: kidney stones bladder tumors other disorders of the urinary ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... to-use and less expensive than other imaging methods. Ultrasound imaging is extremely safe and does not ... barium exams, CT scanning , and MRI are the methods of choice in such a setting. Large patients ...

  20. Ultrasound -- Pelvis

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    Full Text Available ... a more in-depth investigation of the uterine cavity . Three-dimensional (3-D) ultrasound permits evaluation of ... that the human ear cannot hear) into the body and then listens for the returning echoes from ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... used when performing a Pap test . A protective cover is placed over the transducer, lubricated with a ... exam. Transrectal: For a transrectal ultrasound, a protective cover is placed over the transducer . It is lubricated ...

  2. Ultrasound -- Pelvis

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    Full Text Available ... extract a sample of cells from organs for laboratory testing. Doppler ultrasound images can help the physician ... by Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... tip of the transducer is smaller than the standard speculum used when performing a Pap test . A ... both sexes without x-ray exposure. Risks For standard diagnostic ultrasound , there are no known harmful effects ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... ovarian cysts and uterine fibroids ovarian or uterine cancers A transvaginal ultrasound is usually performed to view ... detect: uterine anomalies uterine scars endometrial polyps fibroids cancer, especially in patients with abnormal uterine bleeding Some ...

  5. Ultrasound -- Pelvis

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    Full Text Available ... legs, neck and/or brain (in infants and children) or within various body organs such as the ... tumors other disorders of the urinary bladder In children, pelvic ultrasound can help evaluate: pelvic masses pelvic ...

  6. Prostate Ultrasound

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    Full Text Available ... rectum. top of page What are some common uses of the procedure? A transrectal ultrasound of the ... the scanner by a cord. Some exams may use different transducers (with different capabilities) during a single ...

  7. Prostate Ultrasound

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    Full Text Available ... less than 20 minutes. top of page What will I experience during and after the procedure? Ultrasound ... in the region of the prostate. A biopsy will add time to the procedure. Rarely, a small ...

  8. Ultrasound -- Pelvis

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    Full Text Available ... ultrasound images are reviewed. top of page What will I experience during and after the procedure? For ... in the region of the prostate. A biopsy will add time to the procedure. If a Doppler ...

  9. Ultrasound -- Pelvis

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    Full Text Available ... insertion. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... will share the results with you. In some cases, the radiologist may discuss results with you at ...

  10. Prostate Ultrasound

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    Full Text Available ... with measurements acquired as needed for any treatment planning. detect an abnormal growth within the prostate. help ... ultrasound , there are no known harmful effects on humans. top of ... Radiation Therapy for Prostate Cancer top ...

  11. Ultrasound -- Pelvis

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    Full Text Available ... the uterus). Sonohysterography allows for a more in-depth investigation of the uterine cavity . Three-dimensional (3- ... fluid). In medicine, ultrasound is used to detect changes in appearance, size or contour of organs, tissues, ...

  12. Prostate Ultrasound

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    Full Text Available ... later laboratory testing. top of page How should I prepare? You should wear comfortable, loose-fitting clothing ... than 20 minutes. top of page What will I experience during and after the procedure? Ultrasound exams ...

  13. Ultrasound -- Pelvis

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    Full Text Available ... needle biopsies , in which needles are used to extract a sample of cells from organs for laboratory ... Any portions that are not wiped off will dry quickly. The ultrasound gel does not usually stain ...

  14. Prostate Ultrasound

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    Full Text Available ... the returning echoes from the tissues in the body. The principles are similar to sonar used by boats and submarines. The ultrasound image is immediately visible on a video display screen ...

  15. Ultrasound -- Pelvis

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    Full Text Available ... the returning echoes from the tissues in the body. The principles are similar to sonar used by boats and submarines. The ultrasound image is immediately visible on a video display screen ...

  16. Ultrasound -- Pelvis

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    Full Text Available ... fluid). In medicine, ultrasound is used to detect changes in appearance, size or contour of organs, tissues, ... the sensitive receiver in the transducer records tiny changes in the sound's pitch and direction. These signature ...

  17. Prostate Ultrasound

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    Full Text Available ... fluid). In medicine, ultrasound is used to detect changes in appearance, size or contour of organs, tissues, ... the sensitive receiver in the transducer records tiny changes in the sound's pitch and direction. These signature ...

  18. Prostate Ultrasound

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    Full Text Available ... safe, noninvasive, and does not use ionizing radiation. This procedure requires little to no special preparation. Leave ... examination, an ultrasound-guided biopsy can be performed. This procedure involves advancing a needle into the prostate ...

  19. Prostate Ultrasound

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    Full Text Available ... collects the sounds that bounce back and a computer then uses those sound waves to create an ... Ultrasound scanners consist of a console containing a computer and electronics, a video display screen and a ...

  20. Ultrasound -- Pelvis

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    Full Text Available ... collects the sounds that bounce back and a computer then uses those sound waves to create an ... Ultrasound scanners consist of a console containing a computer and electronics, a video display screen and a ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... abdomen, arms, legs, neck and/or brain (in infants and children) or within various body organs such ... and monitoring of pregnant women and their unborn babies. Ultrasound provides real-time imaging, making it a ...

  2. Prostate Ultrasound

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    Full Text Available ... physician during a routine physical exam or prostate cancer screening exam. an elevated blood test result. difficulty urinating. Because ultrasound provides real-time images, it also can be used to guide ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... quickly. The ultrasound exam room may have a television. Feel free to ask for your child's favorite ... display screen that looks like a computer or television monitor. The image is created based on the ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the ... the transducer (the device placed on the patient's skin to send and receive the returning sound waves), ...

  5. Prostate Ultrasound

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    Full Text Available ... probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the ... the transducer (the device placed on the patient's skin to send and receive the returning sound waves), ...

  6. Ultrasound -- Pelvis

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    Full Text Available ... direction and speed of blood cells as they move through vessels. The movement of blood cells causes ... ultrasound exams, you will be positioned lying face-up on an examination table that can be tilted ...

  7. Prostate Ultrasound

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    Full Text Available ... the prostate is enlarged, also known as benign prostatic hyperplasia (BPH) , with measurements acquired as needed for any ... size with caption Related Articles and Media Benign Prostatic Hyperplasia (BPH) (Enlargement of the Prostate) Prostate Cancer Ultrasound- ...

  8. Ultrasound -- Pelvis

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    Full Text Available ... The principles are similar to sonar used by boats and submarines. The ultrasound image is immediately visible ... principles involved in the sonar used by bats, ships and fishermen. When a sound wave strikes an ...

  9. Prostate Ultrasound

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    Full Text Available ... The principles are similar to sonar used by boats and submarines. The ultrasound image is immediately visible ... principles involved in the sonar used by bats, ships and fishermen. When a sound wave strikes an ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... These exams are frequently used to evaluate the reproductive and urinary systems. Ultrasound is safe, noninvasive and ... identify and evaluate a variety of urinary and reproductive system disorders in both sexes without x-ray ...

  11. Ultrasound -- Pelvis

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    Full Text Available ... frequently used to evaluate the reproductive and urinary systems. Ultrasound is safe, noninvasive and does not use ... and evaluate a variety of urinary and reproductive system disorders in both sexes without x-ray exposure. ...

  12. Prostate Ultrasound

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    Full Text Available ... abnormal area in the prostate gland for later laboratory testing. top of page How should I prepare? ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ...

  13. Ultrasound -- Pelvis

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    Full Text Available ... of the reflected sound waves (called the Doppler effect). A computer collects and processes the sounds and ... standard diagnostic ultrasound , there are no known harmful effects on humans. top of page What are the ...

  14. Ultrasound -- Pelvis

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    Full Text Available ... is sometimes seen in infections top of page How should I prepare? You should wear comfortable, loose- ... sheath and lubricated before insertion. top of page How does the procedure work? Ultrasound imaging is based ...

  15. Prostate Ultrasound

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    Full Text Available ... gland for later laboratory testing. top of page How should I prepare? You should wear comfortable, loose- ... and lubricated with a gel. top of page How does the procedure work? Ultrasound imaging is based ...

  16. Prostate Ultrasound

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    Full Text Available ... uses sound waves to produce pictures of a man’s prostate gland and to help diagnose symptoms such ... also called transrectal ultrasound, provides images of a man's prostate gland and surrounding tissue. The exam typically ...

  17. Ultrasound -- Pelvis

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    Full Text Available ... safe and painless, and produces pictures of the inside of the body using sound waves. Ultrasound imaging, ... capabilities) during a single exam. The transducer sends out high-frequency sound waves (that the human ear ...

  18. Ultrasound -- Pelvis

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    Full Text Available ... sonography , involves the use of a small transducer (probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through the gel into the body. The transducer ...

  19. Prostate Ultrasound

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    Full Text Available ... sonography , involves the use of a small transducer (probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through the gel into the body. The transducer ...

  20. Ultrasound -- Pelvis

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    Full Text Available ... sends out high-frequency sound waves (that the human ear cannot hear) into the body and then ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of ...

  1. Prostate Ultrasound

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    Full Text Available ... sends out high-frequency sound waves (that the human ear cannot hear) into the body and then ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of ...

  2. Prostate Ultrasound

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    Full Text Available ... difficulty urinating or an elevated blood test result. It’s also used to investigate a nodule found during ... difficulty urinating. Because ultrasound provides real-time images, it also can be used to guide procedures such ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... the examination process. To ensure a smooth experience, it often helps to explain the procedure to the ... on the amplitude (loudness), frequency (pitch) and time it takes for the ultrasound signal to return from ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... images may also be saved. The same principles apply to ultrasound procedures such as transrectal and transvaginal ... supervise and interpret radiology examinations) or sonographer will apply a warm water-based gel to the area ...

  5. Ultrasound -- Pelvis

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    Full Text Available ... the amplitude (loudness), frequency (pitch) and time it takes for the ultrasound signal to return from the ... and/or your insurance provider to get a better understanding of the possible charges you will incur. ...

  6. Prostate Ultrasound

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    Full Text Available ... use of a small transducer (probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through the gel into the body. The transducer collects the sounds ...

  7. Ultrasound -- Pelvis

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    Full Text Available ... use of a small transducer (probe) and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through the gel into the body. The transducer collects the sounds ...

  8. Ultrasound -- Pelvis

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    Full Text Available ... of page What are some common uses of the procedure? In women, a pelvic ultrasound is most ... seen in infections top of page How should I prepare? You should wear comfortable, loose-fitting clothing ...

  9. Ultrasound -- Pelvis

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    Full Text Available ... ultrasound exams, you will be positioned lying face-up on an examination table that can be tilted ... you at the conclusion of your examination. Follow-up examinations may be necessary. Your doctor will explain ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... abdomen, arms, legs, neck and/or brain (in infants and children) or within various body organs such as the liver or ... tubes bladder Pelvic ultrasound exams are also used to ...

  11. Prostate Ultrasound

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    Full Text Available ... examination is complete, you may be asked to dress and wait while the ultrasound images are reviewed. ... the following text box: Comment: E-mail: Area code: Phone no: Thank you! Do you have a ...

  12. Ultrasound -- Pelvis

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    Full Text Available ... examination is complete, you may be asked to dress and wait while the ultrasound images are reviewed. ... the following text box: Comment: E-mail: Area code: Phone no: Thank you! Do you have a ...

  13. Ultrasound -- Pelvis

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    Full Text Available ... and ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe ... during a single exam. The transducer sends out high-frequency sound waves (that the human ear cannot ...

  14. Prostate Ultrasound

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    Full Text Available ... gel. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... as detailed as with the transrectal probe. An MRI of the pelvis may be obtained as an ...

  15. Ultrasound -- Pelvis

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    Full Text Available ... insertion. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... In most cases, barium exams, CT scanning , and MRI are the methods of choice in such a ...

  16. Prostate Ultrasound

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    Full Text Available ... to investigate a nodule found during a rectal exam, detect abnormalities, and determine whether the gland is ... a man's prostate gland and surrounding tissue. The exam typically requires insertion of an ultrasound probe into ...

  17. Prostate Ultrasound

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    Full Text Available ... of the prostate uses sound waves to produce pictures of a man’s prostate gland and to help ... Prostate? Ultrasound is safe and painless, and produces pictures of the inside of the body using sound ...

  18. Ultrasound -- Pelvis

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    Full Text Available ... of the pelvis uses sound waves to produce pictures of the structures and organs in the lower ... Imaging? Ultrasound is safe and painless, and produces pictures of the inside of the body using sound ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... or within various body organs such as the liver or kidneys. top of page What are some ... object is solid or filled with fluid). In medicine, ultrasound is used to detect changes in appearance, ...

  20. Ultrasound -- Pelvis

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    Full Text Available ... in x-rays ), thus there is no radiation exposure to the patient. Because ultrasound images are captured ... of the reflected sound waves (called the Doppler effect). A computer collects and processes the sounds and ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... of urinary and reproductive system disorders in both sexes without x-ray exposure. Risks For standard diagnostic ... have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media Sonohysterography Ultrasound - ...

  2. Prostate Ultrasound

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    Full Text Available ... Leave jewelry at home and wear loose, comfortable clothing. You may be asked to wear a gown ... I prepare? You should wear comfortable, loose-fitting clothing for your ultrasound exam. You may need to ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... Leave jewelry at home and wear loose, comfortable clothing. You may be asked to wear a gown. ... I prepare? You should wear comfortable, loose-fitting clothing for your ultrasound exam. You may need to ...

  4. Prostate Ultrasound

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    Full Text Available ... the prostate gland which is situated right in front of the rectum. top of page What are ... men, the prostate gland is located directly in front of the rectum, so the ultrasound exam is ...

  5. Prostate Ultrasound

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    Full Text Available ... biopsy is planned, you may be told to avoid aspirin and other blood thinners for seven to ... abnormal growth within the prostate. help diagnose the cause of a man's infertility. A transrectal ultrasound of ...

  6. Prostate Ultrasound

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    Full Text Available ... Ultrasound Imaging? Men who have had the tail end of their bowel (rectum) removed during prior surgery ... or suggestion into the following text box: Comment: E-mail: Area code: Phone no: Thank you! Please ...

  7. Ultrasound -- Pelvis

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    Full Text Available ... called color Doppler ultrasonography, is a special ultrasound technique that allows the physician to see and evaluate ... evaluation with additional views or a special imaging technique. A follow-up examination may also be necessary ...

  8. Prostate Ultrasound

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    Full Text Available ... elevated blood test result. It’s also used to investigate a nodule found during a rectal exam, detect ... as needle biopsies and fluid aspiration. Risks For standard diagnostic ultrasound , there are no known harmful effects ...

  9. Prostate Ultrasound

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    Full Text Available ... BPH) , with measurements acquired as needed for any treatment planning. detect an abnormal growth within the prostate. help diagnose the cause of a man's infertility. A transrectal ultrasound of the prostate gland is ...

  10. Ultrasound -- Pelvis

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    Full Text Available ... a sample of cells from organs for laboratory testing. Doppler ultrasound images can help the physician to ... the exam. Bringing books, small toys, music or games can help to distract the child and make ...

  11. Prostate Ultrasound

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    Full Text Available ... information you were looking for? Yes No Please type your comment or suggestion into the following text box: Comment: ... Images related to Ultrasound - Prostate Sponsored by Please ...

  12. Ultrasound -- Pelvis

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    Full Text Available ... also used to guide procedures such as needle biopsies , in which needles are used to extract a ... gynecologic examination. For a transrectal exam: If no biopsy is required, transrectal ultrasound of the prostate is ...

  13. Prostate Ultrasound

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    Full Text Available ... requested the exam. Usually, the referring physician or health care provider will share the results with you. ... well on x-ray images. Ultrasound causes no health problems and may be repeated as often as ...

  14. Ultrasound -- Pelvis

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    Full Text Available ... arteries and veins in the abdomen, arms, legs, neck and/or brain (in infants and children) or ... diagnose symptoms experienced by women such as: pelvic pain abnormal vaginal bleeding other menstrual problems Ultrasound exams ...

  15. Prostate Ultrasound

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    Full Text Available ... records tiny changes in the sound's pitch and direction. These signature waves are instantly measured and displayed ... may be present in the sperm or urine following the procedure. After an ultrasound examination, you should ...

  16. Ultrasound -- Pelvis

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    Full Text Available ... in the abdomen, arms, legs, neck and/or brain (in infants and children) or within various body organs ... or uterine cancers A transvaginal ultrasound is usually performed to view ...

  17. Ultrasound -- Pelvis

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    Full Text Available ... uterine cavity . Three-dimensional (3-D) ultrasound permits evaluation of the uterus and ovaries in planes that ... a special study usually done to provide detailed evaluation of the prostate gland, involves inserting a specialized ...

  18. Ultrasound -- Pelvis

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    Full Text Available ... ultrasound exams are also used to monitor the health and development of an embryo or fetus during ... requested the exam. Usually, the referring physician or health care provider will share the results with you. ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... of the body's internal organs, as well as blood flowing through blood vessels. Ultrasound imaging is a noninvasive medical test ... that allows the physician to see and evaluate blood flow through arteries and veins in the abdomen, ...

  20. Prostate Ultrasound

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    Full Text Available ... obtain high-quality images, an ultrasound transducer – a plastic cylinder about the size of a finger – is ... side with your knees bent. A disposable protective cover is placed over the transducer, it is lubricated, ...

  1. Prostate Ultrasound

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    Full Text Available ... echoes from the tissues in the body. The principles are similar to sonar used by boats and ... work? Ultrasound imaging is based on the same principles involved in the sonar used by bats, ships ...

  2. Ultrasound -- Pelvis

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    Full Text Available ... echoes from the tissues in the body. The principles are similar to sonar used by boats and ... work? Ultrasound imaging is based on the same principles involved in the sonar used by bats, ships ...

  3. Prostate Ultrasound

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    Full Text Available ... physician during a routine physical exam or prostate cancer screening exam. an elevated blood test result. difficulty ... vessels or to detect abnormal masses, such as tumors. In an ultrasound examination, a transducer both sends ...

  4. Ultrasound -- Pelvis

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    Full Text Available ... bladder Pelvic ultrasound exams are also used to monitor the health and development of an embryo or ... screen that looks like a computer or television monitor. The image is created based on the amplitude ( ...

  5. Prostate Ultrasound

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    Full Text Available ... is safe, noninvasive, and does not use ionizing radiation. This procedure requires little to no special preparation. ... an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is ...

  6. Ultrasound -- Pelvis

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    Full Text Available ... is safe, noninvasive and does not use ionizing radiation. This procedure requires little to no special preparation. ... an image. Ultrasound examinations do not use ionizing radiation (as used in x-rays ), thus there is ...

  7. Ultrasound -- Pelvis

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    Full Text Available ... are obtained from different orientations to get the best views of the uterus and ovaries. Transvaginal ultrasound ... over time. Follow-up examinations are sometimes the best way to see if treatment is working or ...

  8. Ultrasound -- Pelvis

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    Full Text Available ... prior to the exam. Bringing books, small toys, music or games can help to distract the child ... time to the procedure. If a Doppler ultrasound study is performed, you may actually hear pulse-like ...

  9. Ultrasound -- Pelvis

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    Full Text Available ... water prior to the examination to fill your bladder. Leave jewelry at home and wear loose, comfortable ... to evaluate the: uterus cervix ovaries fallopian tubes bladder Pelvic ultrasound exams are also used to monitor ...

  10. Prostate Ultrasound

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    Full Text Available ... gel. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... creates a real-time picture on the monitor. One or more frames of the moving pictures are ...

  11. Ultrasound -- Pelvis

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    Full Text Available ... insertion. top of page How does the procedure work? Ultrasound imaging is based on the same principles ... creates a real-time picture on the monitor. One or more frames of the moving pictures are ...

  12. Ultrasound -- Pelvis

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    Full Text Available ... in the abdomen, arms, legs, neck and/or brain (in infants and children) or within various body ... ovarian cysts and uterine fibroids ovarian or uterine cancers A transvaginal ultrasound is usually performed to view ...

  13. Ultrasound -- Pelvis

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    Full Text Available ... areas of the body while other areas, especially air-filled lungs, are poorly suited for ultrasound. For ... make secure contact with the body and eliminate air pockets between the transducer and the skin that ...

  14. Prostate Ultrasound

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    Full Text Available ... of page How is the procedure performed? In men, the prostate gland is located directly in front ... What are the limitations of Prostate Ultrasound Imaging? Men who have had the tail end of their ...

  15. Ultrasound -- Pelvis

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    Full Text Available ... or sonography , involves the use of a small transducer (probe) and ultrasound gel placed directly on the ... probe through the gel into the body. The transducer collects the sounds that bounce back and a ...

  16. Prostate Ultrasound

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    Full Text Available ... prostate. help diagnose the cause of a man's infertility. A transrectal ultrasound of the prostate gland is ... of page How is the procedure performed? In men, the prostate gland is located directly in front ...

  17. Prostate Ultrasound

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    Full Text Available ... ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through ... a single exam. The transducer sends out high-frequency sound waves (that the human ear cannot hear) ...

  18. Ultrasound -- Pelvis

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    Full Text Available ... ultrasound gel placed directly on the skin. High-frequency sound waves are transmitted from the probe through ... a single exam. The transducer sends out high-frequency sound waves (that the human ear cannot hear) ...

  19. Ultrasound -- Pelvis

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    Full Text Available ... are reviewed. top of page What will I experience during and after the procedure? For a transabdominal ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of ...

  20. Prostate Ultrasound

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    Full Text Available ... console containing a computer and electronics, a video display screen and a transducer that is used to ... ultrasound image is immediately visible on a video display screen that looks like a computer or television ...

  1. Ultrasound -- Pelvis

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    Full Text Available ... console containing a computer and electronics, a video display screen and a transducer that is used to ... ultrasound image is immediately visible on a video display screen that looks like a computer or television ...

  2. RadNet Air Data From Salt Lake City, UT

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Salt Lake City, UT from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  3. Identification of a Second DNA Binding Site in the Human Rad52 Protein*S⃞

    OpenAIRE

    Kagawa, Wataru; Kagawa, Ako; Saito, Kengo; Ikawa, Shukuko; Shibata, Takehiko; Kurumizaka, Hitoshi; Yokoyama, Shigeyuki

    2008-01-01

    Rad52 plays essential roles in homology-dependent double-strand break repair. Various studies have established the functions of Rad52 in Rad51-dependent and Rad51-independent repair processes. However, the precise molecular mechanisms of Rad52 in these processes remain unknown. In the present study we have identified a novel DNA binding site within Rad52 by a structure-based alanine scan mutagenesis. This site is closely aligned with the putative single-stranded DNA binding ...

  4. General Ultrasound Imaging

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    Full Text Available ... data into 3-D images. A Doppler ultrasound study may be part of an ultrasound examination. Doppler ultrasound , also called color Doppler ultrasonography, is a special ultrasound technique that ...

  5. General Ultrasound Imaging

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    Full Text Available ... are the limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and painless, ... top of page What are some common uses of the procedure? Ultrasound examinations can help to diagnose ...

  6. General Ultrasound Imaging

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    Full Text Available ... Index A-Z General Ultrasound Ultrasound imaging uses sound waves to produce pictures of the inside of ... pictures of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or ...

  7. General Ultrasound Imaging

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    Full Text Available ... of an ultrasound examination. Doppler ultrasound , also called color Doppler ultrasonography, is a special ultrasound technique that ... kidneys. There are three types of Doppler ultrasound: Color Doppler uses a computer to convert Doppler measurements ...

  8. General Ultrasound Imaging

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    Full Text Available ... A-Z General Ultrasound Ultrasound imaging uses sound waves to produce pictures of the inside of the ... of the inside of the body using sound waves. Ultrasound imaging, also called ultrasound scanning or sonography , ...

  9. General Ultrasound Imaging

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    Full Text Available ... What are the limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and ... be heard with every heartbeat. top of page What are some common uses of the procedure? Ultrasound ...

  10. Aktsiisiseaduse muudatused 2006. aastal : aktsiisimäärad / Urmas Koidu

    Index Scriptorium Estoniae

    Koidu, Urmas

    2006-01-01

    2006. aastal jõustunud alkoholi-, tubaka- ja kütuseaktsiisi seaduse muudatustest. Lisatud tabelid: alkoholi aktsiisimäärad Eestis 2006-2008 ja ELi aktsiisi alammäärad (krooni); tubakatoodete aktsiisimäärad Eestis 2006-2008 ja ELi aktsiisi alammäärad; mootorikütuse aktsiisimäärad Eestis ja ELi alammäärad; kütteainete ja elektrienergia aktsiisimäärad Eestis ja ELi alammäärad

  11. Prostate cancer gene 3 (PCA3) is of additional predictive value in patients with PI-RADS grade III (intermediate) lesions in the MR-guided re-biopsy setting for prostate cancer.

    Science.gov (United States)

    Kaufmann, S; Bedke, J; Gatidis, S; Hennenlotter, J; Kramer, U; Notohamiprodjo, M; Nikolaou, K; Stenzl, A; Kruck, S

    2016-04-01

    Multiparametric magnetic resonance imaging (mpMRI) improves diagnostic accuracy in re-biopsies of men with prostate cancer (PC) suspicion, but predictive value is limited despite the use of the new Prostate Imaging Reporting and Data System (PI-RADS). Prognostic value of the PC-specific biomarker prostate cancer gene 3 (PCA3) added to the PI-RADS score was evaluated. The study was a retrospective analysis of the institutional database for men with MR-guided biopsy (MR-GB) for suspicious lesion in mpMRI and who had an additional pre-MR-GB PCA3 testing for ongoing PC suspicion. All men had ≥ 1 negative ultrasound GB. Lesions were retrospectively scored by PI-RADS in three MRI sequences (T2w, DCE, and DWI). PCA3 was analyzed with cutoffs of 25 and 35. The prognostic value of mpMRI and PCA3 and the additional value of both were explored. Tumor detection rate (49 men, mean PSA 10 ng/ml, lesion size 40 mm(2)) was 45 % (22/49 patients). In the subgroup of PI-RADS IV°, 17/17 patients had PC; in PI-RADS III° (intermediate) 5/15 had PC, and all 5 had a PCA3 > 35. PCA3 > 35 had no additional prognostic value in the whole cohort. Out of the 10/15 PC negative patients (PI-RADS III°), PCA3 was PI-RADS III° patients improved predictive accuracy to 91.8 %. MpMRI and subsequent grading to PI-RADS significantly improves PC detection in the re-biopsy setting. The diagnostic uncertainty in the PI-RADS intermediate group can be ameliorated by the addition of PCA3 cutoff of 35 to avoid potential unnecessary biopsies.

  12. Mongoose: Creation of a Rad-Hard MIPS R3000

    Science.gov (United States)

    Lincoln, Dan; Smith, Brian

    1993-01-01

    This paper describes the development of a 32 Bit, full MIPS R3000 code-compatible Rad-Hard CPU, code named Mongoose. Mongoose progressed from contract award, through the design cycle, to operational silicon in 12 months to meet a space mission for NASA. The goal was the creation of a fully static device capable of operation to the maximum Mil-883 derated speed, worst-case post-rad exposure with full operational integrity. This included consideration of features for functional enhancements relating to mission compatibility and removal of commercial practices not supported by Rad-Hard technology. 'Mongoose' developed from an evolution of LSI Logic's MIPS-I embedded processor, LR33000, code named Cobra, to its Rad-Hard 'equivalent', Mongoose. The term 'equivalent' is used to infer that the core of the processor is functionally identical, allowing the same use and optimizations of the MIPS-I Instruction Set software tool suite for compilation, software program trace, etc. This activity was started in September of 1991 under a contract from NASA-Goddard Space Flight Center (GSFC)-Flight Data Systems. The approach affected a teaming of NASA-GSFC for program development, LSI Logic for system and ASIC design coupled with the Rad-Hard process technology, and Harris (GASD) for Rad-Hard microprocessor design expertise. The program culminated with the generation of Rad-Hard Mongoose prototypes one year later.

  13. Rad51 supports triple negative breast cancer metastasis

    Science.gov (United States)

    Wiegmans, Adrian P; Al-Ejeh, Fares; Chee, Nicole; Yap, Pei-Yi; Gorski, Julia J; Silva, Leonard Da; Bolderson, Emma; Chenevix-Trench, Georgia; Anderson, Robin; Simpson, Peter T; Lakhani, Sunil R; Khanna, Kum Kum

    2014-01-01

    In contrast to extensive studies on familial breast cancer, it is currently unclear whether defects in DNA double strand break (DSB) repair genes play a role in sporadic breast cancer development and progression. We performed analysis of immunohistochemistry in an independent cohort of 235 were sporadic breast tumours. This analysis suggested that RAD51 expression is increased during breast cancer progression and metastasis and an oncogenic role for RAD51 when deregulated. Subsequent knockdown of RAD51 repressed cancer cell migration in vitro and reduced primary tumor growth in a syngeneic mouse model in vivo. Loss of RAD51 also inhibited associated metastasis not only in syngeneic mice but human xenografts and changed the metastatic gene expression profile of cancer cells, consistent with inhibition of distant metastasis. This demonstrates for the first time a new function of RAD51 that may underlie the proclivity of patients with RAD51 overexpression to develop distant metastasis. RAD51 is a potential biomarker and attractive drug target for metastatic triple negative breast cancer, with the capability to extend the survival of patients, which is less than 6 months. PMID:24811120

  14. Evolution of RAD- and DIV-Like Genes in Plants

    Directory of Open Access Journals (Sweden)

    Ao Gao

    2017-09-01

    Full Text Available Developmental genetic studies of Antirrhinum majus demonstrated that two transcription factors from the MYB gene family, RADIALIS (RAD and DIVIRICATA (DIV, interact through antagonism to regulate floral dorsoventral asymmetry. Interestingly, similar antagonistic interaction found among proteins of FSM1 (RAD-like and MYBI (DIV-like in Solanum lycopersicum is involved in fruit development. Here, we report the reconstruction of the phylogeny of I-box-like and R-R-type clades, where RAD- and DIV-like genes belong, respectively. We also examined the homology of these antagonistic MYB proteins using these phylogenies. The results show that there are likely three paralogs of RAD-/I-box-like genes, RAD1, RAD2, and RAD3, which originated in the common ancestor of the core eudicots. In contrast, R-R-type sequences fall into two major clades, RR1 and RR2, the result of gene duplication in the common ancestor of both monocots and dicots. RR1 was divided into clades RR1A, RR1B, and RR1C, while RR2 was divided into clades RR2A/DIV1, RR2B/DIV2, and RR2C/DIV3. We demonstrate that among similar antagonistic interactions in An. Majus and So. lycopersicum, RAD-like genes originate from the RAD2 clade, while DIV-like genes originate from distantly related paralogs of the R-R-type lineage. The phylogenetic analyses of these two MYB clades lay the foundation for future comparative studies including testing the evolution of the antagonistic relationship of proteins.

  15. VetCompass Australia: A National Big Data Collection System for Veterinary Science.

    Science.gov (United States)

    McGreevy, Paul; Thomson, Peter; Dhand, Navneet K; Raubenheimer, David; Masters, Sophie; Mansfield, Caroline S; Baldwin, Timothy; Soares Magalhaes, Ricardo J; Rand, Jacquie; Hill, Peter; Peaston, Anne; Gilkerson, James; Combs, Martin; Raidal, Shane; Irwin, Peter; Irons, Peter; Squires, Richard; Brodbelt, David; Hammond, Jeremy

    2017-09-26

    VetCompass Australia is veterinary medical records-based research coordinated with the global VetCompass endeavor to maximize its quality and effectiveness for Australian companion animals (cats, dogs, and horses). Bringing together all seven Australian veterinary schools, it is the first nationwide surveillance system collating clinical records on companion-animal diseases and treatments. VetCompass data service collects and aggregates real-time, clinical records for researchers to interrogate, delivering sustainable and cost-effective access to data from hundreds of veterinary practitioners nationwide. Analysis of these clinical records will reveal geographical and temporal trends in the prevalence of inherited and acquired diseases, identify frequently prescribed treatments, revolutionize clinical auditing, help the veterinary profession to rank research priorities, and assure evidence-based companion-animal curricula in veterinary schools. VetCompass Australia will progress in three phases: (1) roll-out of the VetCompass platform to harvest Australian veterinary clinical record data; (2) development and enrichment of the coding (data-presentation) platform; and (3) creation of a world-first, real-time surveillance interface with natural language processing (NLP) technology. The first of these three phases is described in the current article. Advances in the collection and sharing of records from numerous practices will enable veterinary professionals to deliver a vastly improved level of care for companion animals that will improve their quality of life.

  16. VetCompass Australia: A National Big Data Collection System for Veterinary Science

    Directory of Open Access Journals (Sweden)

    Paul McGreevy

    2017-09-01

    Full Text Available VetCompass Australia is veterinary medical records-based research coordinated with the global VetCompass endeavor to maximize its quality and effectiveness for Australian companion animals (cats, dogs, and horses. Bringing together all seven Australian veterinary schools, it is the first nationwide surveillance system collating clinical records on companion-animal diseases and treatments. VetCompass data service collects and aggregates real-time, clinical records for researchers to interrogate, delivering sustainable and cost-effective access to data from hundreds of veterinary practitioners nationwide. Analysis of these clinical records will reveal geographical and temporal trends in the prevalence of inherited and acquired diseases, identify frequently prescribed treatments, revolutionize clinical auditing, help the veterinary profession to rank research priorities, and assure evidence-based companion-animal curricula in veterinary schools. VetCompass Australia will progress in three phases: (1 roll-out of the VetCompass platform to harvest Australian veterinary clinical record data; (2 development and enrichment of the coding (data-presentation platform; and (3 creation of a world-first, real-time surveillance interface with natural language processing (NLP technology. The first of these three phases is described in the current article. Advances in the collection and sharing of records from numerous practices will enable veterinary professionals to deliver a vastly improved level of care for companion animals that will improve their quality of life.

  17. Empirical assessment of RAD sequencing for interspecific phylogeny.

    Science.gov (United States)

    Cruaud, Astrid; Gautier, Mathieu; Galan, Maxime; Foucaud, Julien; Sauné, Laure; Genson, Gwenaëlle; Dubois, Emeric; Nidelet, Sabine; Deuve, Thierry; Rasplus, Jean-Yves

    2014-05-01

    Next-generation sequencing opened up new possibilities in phylogenetics; however, choosing an appropriate method of sample preparation remains challenging. Here, we demonstrate that restriction-site-associated DNA sequencing (RAD-seq) generates useful data for phylogenomics. Analysis of our RAD library using current bioinformatic and phylogenetic tools produced 400× more sites than our Sanger approach (2,262,825 nt/species), fully resolving relationships between 18 species of ground beetles (divergences up to 17 My). This suggests that RAD-seq is promising to infer phylogeny of eukaryotic species, though potential biases need to be evaluated and new methodologies developed to take full advantage of such data.

  18. RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

    DEFF Research Database (Denmark)

    Bhowmick, Rahul; Minocherhomji, Sheroy; Hickson, Ian D

    2016-01-01

    Homologous recombination (HR) is necessary to counteract DNA replication stress. Common fragile site (CFS) loci are particularly sensitive to replication stress and undergo pathological rearrangements in tumors. At these loci, replication stress frequently activates DNA repair synthesis in mitosis...... replication stress at CFS loci during S-phase. In contrast, MiDAS is RAD52 dependent, and RAD52 is required for the timely recruitment of MUS81 and POLD3 to CFSs in early mitosis. Our results provide further mechanistic insight into MiDAS and define a specific function for human RAD52. Furthermore, selective...

  19. Ultrasound -- Pelvis

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    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician ... blood vessels. Ultrasound imaging is a noninvasive medical test that helps physicians diagnose and treat medical conditions. ...

  20. Prostate Ultrasound

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    Full Text Available ... cells (tissue) from an abnormal area in the prostate gland for later laboratory testing. top of page How should I prepare? You should wear comfortable, loose-fitting clothing for your ultrasound exam. You may need to remove all clothing and jewelry in the area to be ...

  1. Ultrasound -- Pelvis

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    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... can help identify: kidney stones bladder tumors other disorders of the urinary bladder In children, pelvic ultrasound ...

  2. Prostate Ultrasound

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    Full Text Available ... do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the ... tissues that do not show up well on x-ray images. Ultrasound causes no health problems and may ...

  3. Ultrasound -- Pelvis

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    Full Text Available ... do not use ionizing radiation (as used in x-rays ), thus there is no radiation exposure to the ... tissues that do not show up well on x-ray images. Ultrasound is the preferred imaging modality for ...

  4. Prostate Ultrasound

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    Full Text Available ... 20 minutes. top of page What will I experience during and after the procedure? Ultrasound exams in ... areas. Outside links: For the convenience of our users, RadiologyInfo .org provides links to relevant websites. RadiologyInfo. ...

  5. Prostate Ultrasound

    Medline Plus

    Full Text Available ... little to no special preparation. Leave jewelry at home and wear loose, comfortable clothing. You may be asked to wear a gown and to lie on your side with your knees toward your chest. To obtain high-quality images, an ultrasound transducer – a plastic cylinder about ...

  6. Prostate Ultrasound

    Medline Plus

    Full Text Available ... blood, may be administered to determine if a patient is at high risk for cancer. In this case, a biopsy is performed and ... patient story here Images × Image Gallery ... Hyperplasia (BPH) (Enlargement of the Prostate) Prostate Cancer Ultrasound- and MRI-Guided Prostate Biopsy Images related ...

  7. Hip Ultrasound

    Science.gov (United States)

    ... prior to the exam. Bringing books, small toys, music or games can help to distract the child and make the time pass quickly. The ultrasound exam room may have a television. Feel free to ask for your child's favorite channel. In the case of an infant, it ...

  8. Ultrasound -- Vascular

    Science.gov (United States)

    ... prior to the exam. Bringing books, small toys, music or games can help to distract the child and make the time pass quickly. The ultrasound exam room may have a television. Feel free to ask for your child's favorite channel. top of page What does the equipment ...

  9. Ultrasound -- Pelvis

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    Full Text Available ... prior to the exam. Bringing books, small toys, music or games can help to distract the child and make the time pass quickly. The ultrasound exam room may have a television. Feel free to ask for your child's favorite channel. top of page What does the equipment ...

  10. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... are frequently used to evaluate the reproductive and urinary systems. Ultrasound is safe, noninvasive and does not use ... help to identify and evaluate a variety of urinary and reproductive system disorders in both sexes without x-ray exposure. ...

  11. Ultrasound -- Pelvis

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    Full Text Available ... noninvasive medical test that helps physicians diagnose and treat medical conditions. There are three types of pelvic ... or within various body organs such as the liver or kidneys. top of page What ... or uterine cancers A transvaginal ultrasound is usually performed to view ...

  12. Ultrasound -- Pelvis

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    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... internal organs, as well as blood flowing through blood vessels. Ultrasound imaging is a noninvasive medical test that ...

  13. Prostate Ultrasound

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... internal organs, as well as blood flowing through blood vessels. Ultrasound imaging is a noninvasive medical test that ...

  14. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... sends out high-frequency sound waves (that the human ear cannot hear) into the body and then listens for the returning echoes from ... ultrasound , there are no known harmful effects on humans. top ... waves as they pass deeper into the body and need to be returned to the transducer ...

  15. Prostate Ultrasound

    Medline Plus

    Full Text Available ... BPH) , with measurements acquired as needed for any treatment planning. detect an abnormal growth within the prostate. help diagnose the cause of a man's infertility. A transrectal ultrasound of the prostate gland is typically used to help diagnose symptoms such as: a nodule felt by a physician ...

  16. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... medicine, ultrasound is used to detect changes in appearance, size or contour of organs, tissues, and vessels ... your body. The transducer is placed on the body and moved back and forth over the area of interest until the desired images are captured. There is usually no discomfort from ...

  17. Prostate Ultrasound

    Medline Plus

    Full Text Available ... medicine, ultrasound is used to detect changes in appearance, size or contour of organs, tissues, and vessels ... as still images. Short video loops of the images may also be saved. The same principles apply to ... of page How is the procedure performed? ...

  18. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... radiation exposure to the patient. Because ultrasound images are captured in real-time, they can show the structure and movement of ... in a known abnormality can be monitored over time. Follow-up examinations are sometimes the best way to see if treatment ...

  19. Prostate Ultrasound

    Medline Plus

    Full Text Available ... symptoms such as difficulty urinating or an elevated blood test result. It’s also used to investigate a nodule ... exam or prostate cancer screening exam. an elevated blood test result. difficulty urinating. Because ultrasound provides real-time ...

  20. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... the amplitude (loudness), frequency (pitch) and time it takes for the ultrasound signal to return from the ... that represent the flow of blood through the blood vessels. top of ... a Pap test . A protective cover is placed over the transducer, ...

  1. Formulating a VET roadmap for the waste and recycling sector: a case study from Queensland, Australia.

    Science.gov (United States)

    Davis, G

    2012-10-01

    Vocational Education and Training (VET) is an essential tool for providing waste management and recycling workers with the necessary skills and knowledge needed to beneficially influence their own employment and career development; and to also ensure productivity and safe working conditions within the organisations in which they are employed. Current training opportunities within Queensland for the sector are limited and not widely communicated or marketed; with other States, particularly Victoria and New South Wales, realising higher numbers of VET enrollments for waste management courses. This paper presents current VET opportunities and trends for the Queensland waste management sector. Results from a facilitated workshop to identify workforce requirements and future training needs organised by the Waste Contractors and Recyclers Association of Queensland (WCRAQ) are also presented and discussion follows on the future training needs of the industry within Queensland. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Vocabulary of Emotions Test (VET: A Cross-cultural Validation in Portuguese and Croatian Contexts

    Directory of Open Access Journals (Sweden)

    Ana Costa

    2011-12-01

    Full Text Available This article discusses the adaptation and cross-cultural validation of the Vocabulary of Emotions Test (VET in the Portuguese and Croatian contexts, an Emotional Intelligence ability measure with 35 items, which assesses individual's ability to understand emotion. Based on Mayer and Salovey's (1997 theoretical framework of emotional intelligence, VET was originally developed in Croatian academic settings by Takšić, Harambašić and Velemir (2003. This study involved 1119 secondary school students, 682 Portuguese and 437 Croatian, attending different grades and courses. Overall, in both Croatian (original version and Portuguese (adapted version contexts, VET evidenced good psychometric properties particularly concerning sensibility, difficulty item analysis and reliability, although slightly better indicators were found in the Croatian original version. Moreover, cultural and gender differences were found, benefiting Portuguese students and girls.

  3. Isolation, characterisation and expression patterns of a RAD51 ortholog from Pleurotus ostreatus

    NARCIS (Netherlands)

    Mikosch, T.S.P.; Sonnenberg, A.S.M.; Griensven, van L.J.L.D.

    2002-01-01

    AB: Using degenerated primers for conserved regions of RecA homologs we have isolated a gene from Pleurotus ostreatus that shows characteristic features of RAD51 homologs. The encoded amino acid sequence of P. ostreatus RAD51 (PoRAD51) shows greatest sequence similarities with RAD51 from Coprinus

  4. Compensatory role for Rad52 during recombinational repair in Ustilago maydis

    DEFF Research Database (Denmark)

    Kojic, Milorad; Mao, Ninghui; Zhou, Qingwen

    2008-01-01

    in spontaneous mutator activity, allelic recombination or meiosis. GFP-Rad51 foci were formed in rad52 cells following DNA damage, but were initially less intense than normal suggesting a possible role for Rad52 in formation of the Rad51 nucleoprotein filament. A search for interacting genes that confer...

  5. LeishVet update and recommendations on feline leishmaniosis.

    Science.gov (United States)

    Pennisi, Maria-Grazia; Cardoso, Luís; Baneth, Gad; Bourdeau, Patrick; Koutinas, Alek; Miró, Guadalupe; Oliva, Gaetano; Solano-Gallego, Laia

    2015-06-04

    Limited data is available on feline leishmaniosis (FeL) caused by Leishmania infantum worldwide. The LeishVet group presents in this report a review of the current knowledge on FeL, the epidemiological role of the cat in L. infantum infection, clinical manifestations, and recommendations on diagnosis, treatment and monitoring, prognosis and prevention of infection, in order to standardize the management of this disease in cats. The consensus of opinions and recommendations was formulated by combining a comprehensive review of evidence-based studies and case reports, clinical experience and critical consensus discussions. While subclinical feline infections are common in areas endemic for canine leishmaniosis, clinical illness due to L. infantum in cats is rare. The prevalence rates of feline infection with L. infantum in serological or molecular-based surveys range from 0% to more than 60%. Cats are able to infect sand flies and, therefore, they may act as a secondary reservoir, with dogs being the primary natural reservoir. The most common clinical signs and clinicopathological abnormalities compatible with FeL include lymph node enlargement and skin lesions such as ulcerative, exfoliative, crusting or nodular dermatitis (mainly on the head or distal limbs), ocular lesions (mainly uveitis), feline chronic gingivostomatitis syndrome, mucocutaneous ulcerative or nodular lesions, hypergammaglobulinaemia and mild normocytic normochromic anaemia. Clinical illness is frequently associated with impaired immunocompetence, as in case of retroviral coinfections or immunosuppressive therapy. Diagnosis is based on serology, polymerase chain reaction (PCR), cytology, histology, immunohistochemistry (IHC) or culture. If serological testing is negative or low positive in a cat with clinical signs compatible with FeL, the diagnosis of leishmaniosis should not be excluded and additional diagnostic methods (cytology, histology with IHC, PCR, culture) should be employed. The most

  6. Comparison of avian biochemical test results with Abaxis VetScan and Hitachi 911 analyzers.

    Science.gov (United States)

    Greenacre, Cheryl B; Flatland, Bente; Souza, Marcy J; Fry, Michael M

    2008-12-01

    To compare results of clinical biochemical analysis using an Abaxis VetScan bench-top analyzer with reagents specifically marketed for avian use and a Hitachi 911 analyzer, plasma (both methods) and whole blood (VetScan method) samples from 20 clinically healthy Hispaniolan Amazon parrots (Amazona ventralis) were analyzed. Correlation between methods was very high (r = 0.9-1.0) for aspartate aminotransferase (AST), calcium, glucose, and uric acid; high (r = 0.7-0.89) for creatine kinase (CK), phosphorus, potassium, and total protein; moderate (r = 0.5-0.69) for globulin; and low (r = 0.3-0.49) for albumin and sodium. VetScan analyzer results for globulin, sodium, and uric acid had a constant negative bias (values below those from the Hitachi method). Based on difference plot analysis, results for AST, calcium, CK, and glucose are comparable. Because 16 of 20 values fell below the lower detection limit of the VetScan analyzer, bile acid data were excluded from analysis. By using a relatively small sample size (0.1 ml whole blood or plasma), the VetScan analyzer offers rapid in-house results, compact size, and ease of operation. For 4 of the most clinically relevant biochemical analytes used in avian medicine (AST, calcium, CK, glucose), it offers reliable values. For an additional 4 analytes (phosphorous, potassium, total protein, uric acid), establishing analyzer-specific reference intervals is recommended. Neither the VetScan nor the Hitachi method is recommended to assess albumin and globulin concentrations.

  7. Mre11-Rad50 complex crystals suggest molecular calisthenics

    NARCIS (Netherlands)

    C. Wyman (Claire); J.H.G. Lebbink (Joyce); R. Kanaar (Roland)

    2011-01-01

    textabstractRecently published crystal structures of different Mre11 and Rad50 complexes show the arrangement of these proteins and imply dramatic ligand-induced rearrangements with important functional consequences.

  8. Mre11-Rad50 complex crystals suggest molecular calisthenics

    OpenAIRE

    Wyman, Claire; Lebbink, Joyce; Kanaar, Roland

    2011-01-01

    Recently published crystal structures of different Mre11 and Rad50 complexes show the arrangement of these proteins and imply dramatic ligand-induced rearrangements with important functional consequences.

  9. Extreme Temperature, Rad-Hard Power Management ASIC Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Ridgetop Group will design a rad-hard Application Specific Integrated Circuit (ASIC) for spacecraft power management that is functional over a temperature range of...

  10. Rapid SNP discovery and genetic mapping using sequenced RAD markers

    National Research Council Canada - National Science Library

    Baird, Nathan A; Etter, Paul D; Atwood, Tressa S; Currey, Mark C; Shiver, Anthony L; Lewis, Zachary A; Selker, Eric U; Cresko, William A; Johnson, Eric A

    2008-01-01

    .... Here we describe the sequencing of restriction-site associated DNA (RAD) tags, which identified more than 13,000 SNPs, and mapped three traits in two model organisms, using less than half the capacity of one Illumina sequencing run...

  11. RadNet Real-Time Monitoring Spectrometry Data Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The RadNet Real-Time Monitoring Spectrometry Data Inventory contains measured data used to identify and measure specific radioactive materials in the atmosphere at...

  12. RadNet (Environmental Radiation Ambient Monitoring System)

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet, formerly Environmental Radiation Ambient Monitoring System (ERAMS), is a national network of monitoring stations that regularly collect air, precipitation,...

  13. RadNet-Air Near Real Time Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet-Air is a national network of air monitoring stations that regularly collect air samples for near real time analysis of radioactivity. The data is transmitted...

  14. Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination.

    Science.gov (United States)

    Acharya, Sonia N; Many, Alexander M; Schroeder, Andrew P; Kennedy, Felicia M; Savytskyy, Oleksandr P; Grubb, Jennifer T; Vincent, Jack A; Friedle, Elizabeth A; Celerin, Martina; Maillet, Daniel S; Palmerini, Heather J; Greischar, Megan A; Moncalian, Gabriel; Williams, R Scott; Tainer, John A; Zolan, Miriam E

    2008-12-01

    The Mre11/Rad50/Nbs1 (MRN) complex is required for eukaryotic DNA double-strand break (DSB) repair and meiotic recombination. We cloned the Coprinus cinereus rad50 gene and showed that it corresponds to the complementation group previously named rad12, identified mutations in 15 rad50 alleles, and mapped two of the mutations onto molecular models of Rad50 structure. We found that C. cinereus rad50 and mre11 mutants arrest in meiosis and that this arrest is Spo11 dependent. In addition, some rad50 alleles form inducible, Spo11-dependent Rad51 foci and therefore must be forming meiotic DSBs. Thus, we think it likely that arrest in both mre11-1 and the collection of rad50 mutants is the result of unrepaired or improperly processed DSBs in the genome and that Rad50 and Mre11 are dispensable in C. cinereus for DSB formation, but required for appropriate DSB processing. We found that the ability of rad50 mutant strains to form Rad51 foci correlates with their ability to promote synaptonemal complex formation and with levels of stable meiotic pairing and that partial pairing, recombination initiation, and synapsis occur in the absence of wild-type Rad50 catalytic domains. Examination of single- and double-mutant strains showed that a spo11 mutation that prevents DSB formation enhances axial element (AE) formation for rad50-4, an allele predicted to encode a protein with intact hook region and hook-proximal coiled coils, but not for rad50-1, an allele predicted to encode a severely truncated protein, or for rad50-5, which encodes a protein whose hook-proximal coiled-coil region is disrupted. Therefore, Rad50 has an essential structural role in the formation of AEs, separate from the DSB-processing activity of the MRN complex.

  15. Rad51 ATP binding but not hydrolysis is required to recruit Rad10 in synthesis-dependent strand annealing sites in S. cerevisiae.

    Science.gov (United States)

    Karlin, Justin; Fischhaber, Paula L

    2013-06-01

    Several modes of eukaryotic of DNA double strand break repair (DSBR) depend on synapsis of complementary DNA. The Rad51 ATPase, the S. cerevisiae homolog of E. coli RecA, plays a key role in this process by catalyzing homology searching and strand exchange between an invading DNA strand and a repair template (e.g. sister chromatid or homologous chromosome). Synthesis dependent strand annealing (SDSA), a mode of DSBR, requires Rad51. Another repair enzyme, the Rad1-Rad10 endonuclease, acts in the final stages of SDSA, hydrolyzing 3' overhanging single-stranded DNA. Here we show in vivo by fluorescence microscopy that the ATP binding function of yeast Rad51 is required to recruit Rad10 SDSA sites indicating that Rad51 pre-synaptic filament formation must occur prior to the recruitment of Rad1-Rad10. Our data also show that Rad51 ATPase activity, an important step in Rad51 filament disassembly, is not absolutely required in order to recruit Rad1-Rad10 to DSB sites.

  16. Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

    DEFF Research Database (Denmark)

    Song, Honglin; Dicks, Ed; Ramus, Susan J

    2015-01-01

    PURPOSE: The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the population and in a screening trial of individuals at high risk of ovarian cancer. PATIENTS AND METHODS: The coding s...

  17. Design Principles for Applied Learning: Bringing Theory and Practice Together in an Online VET Teacher-Education Degree

    Science.gov (United States)

    Downing, Jillian J.

    2017-01-01

    This paper reports on a doctoral study that investigated an alternative pedagogical approach in an online VET teacher-education course offered at a mid-sized university in Australia. Students in the course were mature-aged and adding study to their role as in-service VET teachers. Building on previous research, a set of design principles was…

  18. Employers' Use and Views of the VET System 2017. Australian Vocational Education and Training Statistics

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2017

    2017-01-01

    This publication presents information on employers' use and views of the vocational education and training (VET) system. The findings relate to the various ways in which Australian employers use the VET system and unaccredited training to meet their skill needs, and their satisfaction with these methods of training. Australian employers can engage…

  19. VET Teacher Education in Australian Universities: Who Are the Students and What Are Their Views about Their Courses?

    Science.gov (United States)

    Smith, Erica; Hodge, Steven; Yasukawa, Keiko

    2015-01-01

    In Australia, the question of the level and nature of qualifications for vocational education and training (VET) teachers is a highly contested and political topic. VET teachers are only required to have a pre-university, certificate level pedagogical qualification, the Certificate IV in Training and Assessment. They possess substantially…

  20. Collaborations between Foreign-Invested Enterprises and China's VET Schools: Making the System Work amid Localised Skill Shortages

    Science.gov (United States)

    Li, Yiqiong; Sheldon, Peter

    2014-01-01

    This article examines collaborative initiatives individual foreign-invested enterprises (FIEs) develop with China's vocational education and training (VET) schools amid localised shortages of skilled workers. It thus focuses on employer initiatives in responding to VET system weaknesses rather than, as is common, those weaknesses. Using Suzhou…

  1. International Students in the Private VET Sector in Melbourne, Australia: Rethinking Their Characteristics and Aspirations outside the Deficit Model

    Science.gov (United States)

    Pasura, Rinos

    2015-01-01

    The reconstruction of the Australian Vocational Education and Training (VET) sector into a competitive training market, which led to the participation of international students and commercial for-profit private VET providers, has until recently focused on the importance of international students to the national economy whilst ignoring the…

  2. Europeanization in VET Policy as a Process of Reshaping the Educational Space

    Directory of Open Access Journals (Sweden)

    Krista Loogma

    2016-04-01

    Full Text Available The EU represents a transforming educational space, where national and supranational boundaries in educational governance are becoming blurred. The EU has become an  important actor in educational governance and an important arena for policy learning and transfer. This paper explores how the process of reshaping the educational space manifests itself in the process of the Europeanization of VET policy in the case of Estonia. In Estonia, this process was followed by the growth of executive VET institutions and has developed from rather uncritical initial policy transfer to more active learning from the EU, although conformism can still be seen in cases of the introduction of standardizing policy tools.

  3. Structured reporting platform improves CAD-RADS assessment.

    Science.gov (United States)

    Szilveszter, Bálint; Kolossváry, Márton; Karády, Júlia; Jermendy, Ádám L; Károlyi, Mihály; Panajotu, Alexisz; Bagyura, Zsolt; Vecsey-Nagy, Milán; Cury, Ricardo C; Leipsic, Jonathon A; Merkely, Béla; Maurovich-Horvat, Pál

    2017-11-01

    Structured reporting in cardiac imaging is strongly encouraged to improve quality through consistency. The Coronary Artery Disease - Reporting and Data System (CAD-RADS) was recently introduced to facilitate interdisciplinary communication of coronary CT angiography (CTA) results. We aimed to assess the agreement between manual and automated CAD-RADS classification using a structured reporting platform. Five readers prospectively interpreted 500 coronary CT angiographies using a structured reporting platform that automatically calculates the CAD-RADS score based on stenosis and plaque parameters manually entered by the reader. In addition, all readers manually assessed CAD-RADS blinded to the automatically derived results, which was used as the reference standard. We evaluated factors influencing reader performance including CAD-RADS training, clinical load, time of the day and level of expertise. Total agreement between manual and automated classification was 80.2%. Agreement in stenosis categories was 86.7%, whereas the agreement in modifiers was 95.8% for "N", 96.8% for "S", 95.6% for "V" and 99.4% for "G". Agreement for V improved after CAD-RADS training (p = 0.047). Time of the day and clinical load did not influence reader performance (p > 0.05 both). Less experienced readers had a higher total agreement as compared to more experienced readers (87.0% vs 78.0%, respectively; p = 0.011). Even though automated CAD-RADS classification uses data filled in by the readers, it outperforms manual classification by preventing human errors. Structured reporting platforms with automated calculation of the CAD-RADS score might improve data quality and support standardization of clinical decision making. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  4. Extracting BI-RADS Features from Portuguese Clinical Texts

    Science.gov (United States)

    Nassif, Houssam; Cunha, Filipe; Moreira, Inês C.; Cruz-Correia, Ricardo; Sousa, Eliana; Page, David; Burnside, Elizabeth; Dutra, Inês

    2013-01-01

    In this work we build the first BI-RADS parser for Portuguese free texts, modeled after existing approaches to extract BI-RADS features from English medical records. Our concept finder uses a semantic grammar based on the BIRADS lexicon and on iterative transferred expert knowledge. We compare the performance of our algorithm to manual annotation by a specialist in mammography. Our results show that our parser’s performance is comparable to the manual method. PMID:23797461

  5. PHELIX Crenulation-1 at pRad Experiment

    Science.gov (United States)

    Rousculp, Christopher

    2016-10-01

    The first PHELIX driven Crenulation experiment was fielded at the LANL LANSCE proton radiography (pRad) facility in Dec 2015. This was the first time a thin-walled tin cylinder with single-mode perturbations was shocked to melt-on-release (P >35 kbar) in converging geometry. The perturbation inversion and growth due to the Richtmyer-Meshkov Instability (RMI) is diagnosed in a 21 image pRad movie. The motivation, design, preliminary data and calculations will be discussed.

  6. RADTRAN 6/RadCat 6 user guide.

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F.; Hinojosa, Daniel; Heames, Terence John; Farnum, Cathy Ottinger; Kalinina, Elena Arkadievna

    2013-09-01

    This document provides a detailed discussion and a guide for the use of the RadCat 6.0 Graphical User Interface input file generator for the RADTRAN code, Version 6. RadCat 6.0 integrates the newest analysis capabilities of RADTRAN 6.0, including an economic model, updated loss-of-lead shielding model, a new ingestion dose model, and unit conversion. As of this writing, the RADTRAN version in use is RADTRAN 6.02.

  7. RAD/COMM ''Cricket'' Test Report

    CERN Document Server

    Chiaro, P J

    2002-01-01

    A series of tests were performed at Oak Ridge National Laboratory (ORNL) to evaluate and characterize the radiological response of a ''Cricket'' radiation detection system. The ''Cricket'' is manufactured by RAD/COMM Systems Corp., which is located in Ontario, Canada. The system is designed to detect radioactive material that may be contained in scrap metal. The Cricket's detection unit is mounted to the base of a grappler and monitors material, while the grappler's tines hold the material. It can also be used to scan material in an attempt to isolate radioactive material if an alarm occurs. Testing was performed at the Environmental Effects Laboratory located at ORNL and operated by the Engineering Science and Technology Division. Tests performed included the following: (1) Background stability, (2) Energy response using sup 2 sup 4 sup 1 Am, sup 1 sup 3 sup 7 Cs, and sup 6 sup 0 Co, (3) Surface uniformity, (4) Angular dependence, (5) Alarm actuation, (6) Alarm threshold vs. background, (7) Shielding, (8) Re...

  8. RAD/COMM Cricket Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Chiaro, PJ

    2003-08-28

    The Environmental Effects Laboratory of the Engineering Science and Technology Division of Oak Ridge National Laboratory performed a series of tests to further evaluate and characterize the radiological response of a ''Cricket'' radiation detection system. The Cricket, manufactured by Rad/Comm Systems Corporation of Ontario, Canada, is designed to detect radioactive material that may be contained in scrap metal. The Cricket's detection unit is designed to be mounted to the base of a grappler, allowing it to monitor material while the material is being held by the grappler tines. The Cricket was tested for background stability, energy response, spherical response, surface uniformity, angular dependence, and alarm actuation. Some of these tests were repeated from a prior test of a Cricket at the Environmental Effects Laboratory as reported in ORNL/TM-2002/94. Routine environmental tests--normal temperature and relatively humidity--were also performed as part of this testing process. Overall, the Cricket performed well during the testing process. The design of the instrument and the inherent photon energy of the radionuclides had some affect on portions of the tests but do not detract from the value-added benefits of the Cricket's detection capabilities.

  9. Improving Breast Ultrasound Interpretation in Uganda Using a Condensed Breast Imaging Reporting and Data System.

    Science.gov (United States)

    Scheel, John R; Peacock, Sue; Orem, Jackson; Bugeza, Samuel; Muyinda, Zeridah; Porter, Peggy L; Wood, William C; Comis, Robert L; Lehman, Constance D

    2016-10-01

    This study aimed to determine whether a 2-day educational course using a condensed Breast Imaging Reporting and Data System (condensed BI-RADS) improved the accuracy of Ugandan healthcare workers interpreting breast ultrasound. The target audience of this intervention was Ugandan healthcare workers involved in performing, interpreting, or acting on the results of breast ultrasound. The educational course consisted of a pretest knowledge assessment, a series of lectures on breast imaging interpretation and standardized reporting using a condensed BI-RADS, and a posttest knowledge assessment. Participants interpreted 53 different ultrasound test cases by selecting the finding type, descriptors for masses, and recommendations. We compared the percent correct on the pretest and posttest based on occupation and training level. Sixty-one Ugandan healthcare workers participated in this study, including 13 radiologists, 13 other physicians, 12 technologists, and 23 midlevel providers. Most groups improved in identifying the finding type (P breast ultrasound education using a condensed BI-RADS improved the interpretive performance of healthcare workers and was particularly successful in reducing the frequency of unnecessary biopsies for normal and benign findings. Multimodal educational efforts to improve accuracy and management of breast ultrasound findings may augment breast cancer early detection efforts in resource-limited settings. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  10. RAD51 interconnects between DNA replication, DNA repair and immunity.

    Science.gov (United States)

    Bhattacharya, Souparno; Srinivasan, Kalayarasan; Abdisalaam, Salim; Su, Fengtao; Raj, Prithvi; Dozmorov, Igor; Mishra, Ritu; Wakeland, Edward K; Ghose, Subroto; Mukherjee, Shibani; Asaithamby, Aroumougame

    2017-05-05

    RAD51, a multifunctional protein, plays a central role in DNA replication and homologous recombination repair, and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cytoplasm, triggering a STING-mediated innate immune response after replication stress and DNA damage. In the absence of RAD51, the unprotected newly replicated genome is degraded by the exonuclease activity of MRE11, and the fragmented nascent DNA accumulates in the cytosol, initiating an innate immune response. Our data suggest that in addition to playing roles in homologous recombination-mediated DNA double-strand break repair and replication fork processing, RAD51 is also implicated in the suppression of innate immunity. Thus, our study reveals a previously uncharacterized role of RAD51 in initiating immune signaling, placing it at the hub of new interconnections between DNA replication, DNA repair, and immunity. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  11. The srs2 suppressor of UV sensitivity acts specifically on the RAD5- and MMS2-dependent branch of the RAD6 pathway

    National Research Council Canada - National Science Library

    Ulrich, H D

    2001-01-01

    .... Loss-of-function mutations in srs2 suppress the extreme sensitivity towards UV radiation of rad6 and rad18 mutants, both of which are impaired in post-replication DNA repair and damage-induced mutagenesis...

  12. Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Zhiyuan; Pardington-Purtymun, P.E.; Comeaux, J.C. [Los Alamos National Labs., NM (United States)] [and others

    1996-10-15

    The yeast RAD52-dependent pathway is involved in DNA recombination and double-strand break repair. Yeast ubiquitin-conjugating enzyme UBC9 participates in S- and M-phase cyclin degradation and mitotic control. Using the human RAD52 protein as the bait in a yeast two-hybrid system, we have identified a human homolog of yeast UBC9, designated UBE2I, that interacts with RAD52, RAD51, p53, and a ubiquitin-like protein UBL1. These interactions are UBE2I-specific, since another DNA repair-related ubiquitin-conjugating enzyme, RAD6 (UBC2), does not interact with these proteins. The interaction of UBE2I with RAD52 is mediated by RAD52`s self-association region. These results suggest that the RAD52-dependent processes, cell cycle control, p53-mediated pathway(s), and ubiquitination interact through human UBE2I. 22 refs., 3 figs.

  13. Lesion morphology on breast MRI affects targeted ultrasound correlation rate

    Energy Technology Data Exchange (ETDEWEB)

    Hollowell, Lauren; Price, Elissa; Arasu, Vignesh; Wisner, Dorota; Hylton, Nola; Joe, Bonnie [UCSF, San Francisco, CA (United States)

    2015-05-01

    Suspicious lesions on breast MRI are often initially evaluated using targeted ultrasound. However, workup varies. Data on the rate of correlate detection by morphology [mass, non-mass enhancement (NME), or focus] would be useful for developing practice guidelines. Breast MRI examinations from 1 January 2008 to 31 December 2010 were reviewed. BI-RADS 4 or 5 lesions on MRI evaluated with targeted ultrasound where definitive diagnosis was obtained were included. Statistical analysis was performed on aggregate data and at the lesion level. A total of 204 lesions were included in the study. A statistically significant difference in ultrasound correlate identification by morphology was found; a correlate was found in 49.3 % of masses, 15 % of NME, and 42.3 % of foci (p = 0.0006). Additional analysis within each morphology demonstrated significantly greater rate of malignancy in masses with an ultrasound correlate than masses without a correlate (p = 0.0062), while the rate of malignancy in NME and foci did not differ with ultrasound correlation. Morphology of a suspicious lesion on breast MRI affects the probability of identifying an ultrasound correlate. As sonographic correlates are found in nearly half of masses and foci, targeted ultrasound should be the initial step in their workup. (orig.)

  14. Governance Dynamics and the Application of the Multilevel Governance Approach in Vocational Education and Training (VET) in the European Neighbourhood Countries: The Case of the ENPI South Region

    Science.gov (United States)

    Galvin Arribas, J. Manuel

    2016-01-01

    This article analyses moves towards good multilevel governance approaches in Vocational Education and Training (VET) as an effective way to improve VET policy making in transition and developing countries, focusing on the Southern Neighbourhood of the EU (ENPI South). The centralised approaches in public administration and to VET governance still…

  15. Digital Reading in PISA 2012 and ICT Uses: How Do VET and General Education Students Perform? JRC Science for Policy Report

    Science.gov (United States)

    Dinis da Costa, Patrícia; Araújo, Luísa

    2016-01-01

    The analyses presented in this report indicate that in several Member States (MS) 15-year-old students in vocational-oriented programmes (VET) perform better in digital reading than in print reading in PISA 2012. When differentiated by programme of study--VET versus general education programmes--VET students perform better in digital than in print…

  16. Evaluation of COTS Rad Detection Apps

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Eric [National Security Technologies, LLC. (NSTec), Mercury, NV (United States)

    2014-02-01

    Mobile applications are currently under distribution to smart phones utilizing the built-in charge coupled-device (CCD) camera as a radiation detector. The CCD detector has a very low but measurable gamma interaction cross section so the mechanism is feasible, especially for higher dose rate environments. Given that in a large release of radioactive material these ‘crowd sourced’ measurements will be put forth for consideration, a testing and evaluation of the accuracy and uncertainty of the Apps is a critical endeavor. Not only is the accuracy of the reported measurement of concern to the immediate user’s safety, a quantitative uncertainty is required for a government response such as the Federal Radiological Monitoring and Assessment Center (FRMAC) to accept the values for consideration in the determination of regions exceeding protective action guidelines. Already, prompted by the Fukushima nuclear material releases, several repositories of this crowd-sourced data have been created (http://japan.failedrobot.com, http://www.stubbytour.com/nuc/index_en.asp, and http://www.rdtn.org) although the question remains as to the reliability of measurements incorporated into these repositories. In cases of conflict between the real-time published crowd-sourced data and governmental protective actions prepared literature should be on-hand documenting why the difference, if any, exists. Four applications for iOS devices were obtained along with hardware to benchmark their performance. Gamma/X-Ray Detector by Stephan Hotto, Geiger Camera by Senscare, and RadioactivityCounter App by Hotray LTD are all the applications available for distribution within the US that utilize the CCD camera sensor for detection of radiation levels. The CellRad app under development by Idaho National Laboratory for the Android platform was evaluated. In addition, iRad Geiger with the associated hardware accessory was also benchmarked. Radiation fields were generated in a Cs-137 JL Shepherd

  17. Effect of bacterial recA expression on DNA repair in the rad51 and rad52 mutants of Saccharomyces cerevisiae

    Directory of Open Access Journals (Sweden)

    Morais Jr. M.A.

    1998-01-01

    Full Text Available Molecular and functional homology between yeast proteins pRad51 and pRad52 and Escherichia coli pRecA involved in recombinational DNA repair led us to investigate possible effects of recA gene expression on DNA repair in rad51 and rad52 mutants of Saccharomyces cerevisiae. The mutant cells were subjected to one of the following treatments: preincubation with 8-methoxypsoralen and subsequent irradiation with 360-nm ultraviolet (UVA (8-MOP + UVA, irradiation with 254-nm UV light or treatment with methyl methane sulfonate (MMS. While recA expression did not repair lethal DNA lesions in mutant rad51, it was able to partially restore resistance to 8-MOP + UVA and MMS in rad52. Expression of recA could not complement the sensitivity of rad51rad52 double mutants, indicating that pRad51 may be essential for the repair-stimulating activity of pRecA in the rad52 mutant. Spontaneous mutagenesis was increased, and 8-MOP-photoinduced mutagenesis was decreased by the presence of pRecA in rad52, whereas pRecA decreased UV-induced mutagenesis in rad51. Thus, pRecA may function in yeast DNA repair either as a member of a protein complex or as an individual protein that binds to mutagen-damaged DNA.

  18. RAD18 mediates resistance to ionizing radiation in human glioma cells

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Chen; Wang, Hongwei; Cheng, Hongbin; Li, Jianhua; Wang, Zhi, E-mail: drzwang@gmail.com; Yue, Wu, E-mail: drwuyue@gmail.com

    2014-02-28

    Highlights: • RAD18 is an important mediator of the IR-induced resistance in glioma cell lines. • RAD18 overexpression confers resistance to IR-mediated apoptosis. • The elevated expression of RAD18 is associated with recurrent GBM who underwent IR therapy. - Abstract: Radioresistance remains a major challenge in the treatment of glioblastoma multiforme (GBM). RAD18 a central regulator of translesion DNA synthesis (TLS), has been shown to play an important role in regulating genomic stability and DNA damage response. In the present study, we investigate the relationship between RAD18 and resistance to ionizing radiation (IR) and examined the expression levels of RAD18 in primary and recurrent GBM specimens. Our results showed that RAD18 is an important mediator of the IR-induced resistance in GBM. The expression level of RAD18 in glioma cells correlates with their resistance to IR. Ectopic expression of RAD18 in RAD18-low A172 glioma cells confers significant resistance to IR treatment. Conversely, depletion of endogenous RAD18 in RAD18-high glioma cells sensitized these cells to IR treatment. Moreover, RAD18 overexpression confers resistance to IR-mediated apoptosis in RAD18-low A172 glioma cells, whereas cells deficient in RAD18 exhibit increased apoptosis induced by IR. Furthermore, knockdown of RAD18 in RAD18-high glioma cells disrupts HR-mediated repair, resulting in increased accumulation of DSB. In addition, clinical data indicated that RAD18 was significantly higher in recurrent GBM samples that were exposed to IR compared with the corresponding primary GBM samples. Collectively, our findings reveal that RAD18 may serve as a key mediator of the IR response and may function as a potential target for circumventing IR resistance in human GBM.

  19. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... flat sections of the body. Advancements in ultrasound technology include three-dimensional (3-D) ultrasound that formats ... modality for the diagnosis and monitoring of pregnant women and their unborn babies. Ultrasound provides real-time ...

  20. Ultrasound guided supraclavicular block.

    LENUS (Irish Health Repository)

    Hanumanthaiah, Deepak

    2013-09-01

    Ultrasound guided regional anaesthesia is becoming increasingly popular. The supraclavicular block has been transformed by ultrasound guidance into a potentially safe superficial block. We reviewed the techniques of performing supraclavicular block with special focus on ultrasound guidance.