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Sample records for vehicle-dependent disposition kinetics

  1. Vehicle-Dependent Disposition Kinetics of Fluoranthene in Fisher-344 Rats

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    Aramandla Ramesh

    2008-03-01

    Full Text Available The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of polycyclic aromatic hydrocarbon chemicals. Fluoranthene exposure to humans may occur as a result of cigarette smoking, consumption of contaminated food and water, heating woods in stoves and boilers, industrial sources such as coal gasification, carbon and graphite electrode manufacturing. Adult male Fisher-344 rats were given single oral doses of 25 and 50 μg/kg FLA in tricaprylin, peanut oil, cod liver oil, tween 80/isotonic saline (1:5 and 2% Alkamuls-EL620 through gavage. After administration, the rats were housed individually in metabolic cages and sacrificed at 2, 4, 6, 8, 10 and 12 hours post FLA exposure. Blood, lung, liver, small intestine, adipose tissue samples, urine, and feces were collected at each time point. Samples were subjected to a liquid-liquid extraction using methanol, chloroform, and water. The extracts were analyzed by a reverse-phase HPLC, equipped with a fluorescence detector. The results revealed a dose-dependent increase in FLA concentrations in plasma and tissues for all the vehicles used. Plasma and tissue FLA concentrations were greater for peanut oil; cod liver oil, and tricaprylin vehicles compared to Alkamuls (p peanut oil > tricaprylin > alkamuls > tween 80/isotonic saline (1:5]. These findings suggest that uptake and elimination of FLA is accelerated when administered through oil-based vehicles. The low uptake of FLA from alkamuls and tween 80/isotonic saline may have been a result of the poor solubility of the chemical. In summary, our findings reiterate that absorption characteristics of FLA were governed by the dose as well as the dosing vehicle. The vehicle-dependent bioavailability of FLA suggests a need for the judicious selection of vehicles in evaluating oral toxicity studies for risk assessment purposes.

  2. Disposition Kinetics of Taxanes in Peritoneal Dissemination

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    Ken'ichi Miyamoto

    2012-01-01

    Full Text Available Treatment of cancers in the abdominal cavity, such as peritoneal dissemination, is difficult, but in principle intraperitoneal administration of anticancer drugs is expected to be preferable to systemic administration. Taxane anticancer drugs are used to treat gastric cancer patients with peritoneal dissemination. They are administered as micellar preparations, Taxol and Taxotere, which consist of paclitaxel in Cremophor EL (crEL and docetaxel in Polysorbate-80 (PS-80, respectively. In this paper we review the disposition kinetics of taxane anticancer drugs after intraperitoneal administration in peritoneal dissemination patients and animal models and also discuss the effect of the surfactant vehicle on the behavior of taxanes.

  3. Fractional kinetics in drug absorption and disposition processes.

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    Dokoumetzidis, Aristides; Macheras, Panos

    2009-04-01

    We explore the use of fractional order differential equations for the analysis of datasets of various drug processes that present anomalous kinetics, i.e. kinetics that are non-exponential and are typically described by power-laws. A fractional differential equation corresponds to a differential equation with a derivative of fractional order. The fractional equivalents of the "zero-" and "first-order" processes are derived. The fractional zero-order process is a power-law while the fractional first-order process is a Mittag-Leffler function. The latter behaves as a stretched exponential for early times and as a power-law for later times. Applications of these two basic results for drug dissolution/release and drug disposition are presented. The fractional model of dissolution is fitted successfully to datasets taken from literature of in vivo dissolution curves. Also, the proposed pharmacokinetic model is fitted to a dataset which exhibits power-law terminal phase. The Mittag-Leffler function describes well the data for small and large time scales and presents an advantage over empirical power-laws which go to infinity as time approaches zero. The proposed approach is compared conceptually with fractal kinetics, an alternative approach to describe datasets with non exponential kinetics. Fractional kinetics offers an elegant description of anomalous kinetics, with a valid scientific basis, since it has already been applied in problems of diffusion in other fields, and describes well the data.

  4. Disposition of smoked cannabis with high [Delta]9-tetrahydrocannabinol content: A kinetic model.

    NARCIS (Netherlands)

    Hunault, C.C.; van Eijkeren, J.C.; Mensinga, T.T.; de Vries, I.; Leenders, M.E.C.; Meulenbelt, J.|info:eu-repo/dai/nl/079479227

    2010-01-01

    Introduction No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing estimates of the THC serum concentrations after smoking cannabis cigarettes containing high THC doses (up to 69 mg THC).Methods

  5. Disposition kinetics of albendazole and metabolites in laying hens.

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    Bistoletti, M; Alvarez, L; Lanusse, C; Moreno, L

    2013-04-01

    An increasing prevalence of roundworm parasites in poultry, particularly in litter-based housing systems, has been reported. However, few anthelmintic drugs are commercially available for use in avian production systems. The anthelmintic efficacy of albendazole (ABZ) in poultry has been demonstrated well. The goal of this work was to characterize the ABZ and metabolites plasma disposition kinetics after treatment with different administration routes in laying hens. Twenty-four laying hens Plymouth Rock Barrada were distributed into three groups and treated with ABZ as follows: intravenously at 10 mg/kg (ABZ i.v.); orally at the same dose (ABZ oral); and in medicated feed at 10 mg/kg·day for 7 days (ABZ feed). Blood samples were taken up to 48 h posttreatment (ABZ i.v. and ABZ oral) and up to 10 days poststart feed medication (ABZ feed). The collected plasma samples were analyzed using high-performance liquid chromatography. ABZ and its albendazole sulphoxide (ABZSO) and ABZSO2 metabolites were recovered in plasma after ABZ i.v. administration. ABZ parent compound showed an initial concentration of 16.4 ± 2.0 μg/mL, being rapidly metabolized into the ABZSO and ABZSO2 metabolites. The ABZSO maximum concentration (Cmax ) (3.10 ± 0.78 μg/mL) was higher than that of ABZSO2 Cmax (0.34 ± 0.05 μg/mL). The area under the concentration vs time curve (AUC) for ABZSO (21.9 ± 3.6 μg·h/mL) was higher than that observed for ABZSO2 and ABZ (7.80 ± 1.02 and 12.0 ± 1.6 μg·h/mL, respectively). The ABZ body clearance (Cl) was 0.88 ± 0.11 L·h/kg with an elimination half-life (T1/2el ) of 3.47 ± 0.73 h. The T1/2el for ABZSO and ABZSO2 were 6.36 ± 1.50 and 5.40 ± 1.90 h, respectively. After ABZ oral administration, low ABZ plasma concentrations were measured between 0.5 and 3 h posttreatment. ABZ was rapidly metabolized to ABZSO (Cmax , 1.71 ± 0.62 μg/mL) and ABZSO2 (Cmax , 0.43 ± 0.04 μg/mL). The metabolite systemic exposure (AUC) values were 18.6 ± 2.0 and 10

  6. In silico prediction of percutaneous absorption and disposition kinetics of chemicals.

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    Chen, Longjian; Han, Lujia; Saib, Ouarda; Lian, Guoping

    2015-05-01

    To develop in-silico model for predicting percutaneous absorption and disposition kinetics of chemicals in skin layers so as to facilitate the design of transdermal drug delivery systems and skin care products, and risk assessment of occupational or consumer exposure. A general-purpose computer model for simulating skin permeation, absorption and disposition kinetics in the stratum corneum, viable dermis and dermis has been developed. Equations have been proposed for determining the partition and diffusion properties of chemicals by considering molecular partition, binding and mobility in skin layers. In vitro skin penetration data of 12 chemicals was used to validate the model. The observed and simulated permeation and disposition in skin layers were compared for 12 tested chemicals. For most tested chemicals, the experimental and model results are in good agreement with the coefficient of determination >0.80 and relative root mean squared error silico simulation of percutaneous permeation, absorption and disposition kinetics of wide chemical space. The model produced results in good agreement with experimental data of 12 chemicals, suggesting a much improved framework to support transdermal delivery of drug and cosmetic actives as well as integrated risk assessment.

  7. Nonlinear disposition kinetics of a novel antifolate, MX-68, in rats.

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    Han, Y H; Kato, Y; Sugiyama, Y

    1999-10-01

    The excretion and tissue distribution kinetics of a novel antifolate, MX-68, were evaluated under conditions of a continuous steady-state infusion in Sprague-Dawley rats (SDRs). The biliary excretion clearance defined with respect to the hepatic concentration (CL(bile, h)) was much lower in Eisai hyperbilirubinemic rats with a hereditary deficiency in canalicular multispecific organic anion transporter than that in SDRs, suggesting the involvement of canalicular multispecific organic anion transporter in its transport across the bile canalicular membrane. The CL(bile, h) in SDRs increased as the infusion rate increased; this can be largely explained by saturation of the intracellular binding of MX-68. On the other hand, the urinary excretion clearance defined with respect to the renal concentration (CL(urine, k)) was comparable for the two strains but showed an increase and subsequent decrease as the renal concentration increased. This nonlinear profile was also found even when the CL(urine, k) was normalized by the unbound fraction in kidney. Therefore, this kinetic profile represents the saturation of both reabsorption and secretion. Reabsorption of MX-68 in kidney was supported by its saturable transport by renal brush border membrane vesicles at an inward H(+) gradient. The liver-to-plasma unbound concentration ratio decreased as the steady-state plasma concentration increased, suggesting that MX-68 is taken up by a saturable mechanism or mechanisms. Thus, the saturation of transport systems across several plasma membranes and intracellular binding in both the liver and kidney produce the nonlinear disposition of MX-68.

  8. Disposition kinetics of long acting moxifloxacin following intravenous administration in Sheep

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    Chirag M. Modi

    Full Text Available Aim: The objective of the present study was to study the disposition kinetics and dosage regimens of long acting moxifloxacin following intravenous administration at the dose rate of 7.5 mg/kg-1 b. wt. in six male sheep and to calculate dosage regimens of the same in sheep. Materials and Methods: The study was conducted using six healthy male sheep. Long acting Moxifloxacin solution (10 % moxifloxacin in solution with L- arginine, N-butyl alcohol and benzyl alcohol was injected in jugular vein and periodical blood samples were collected from contra-lateral jugular vein in test tubes containing 30-50 IU heparin (anticoagulant at 0.083 (5 min, 0.166 (10 min, 0.5, 1, 2, 4, 8, 12, 24, 36, 48, 60, 72 and up to 96 h post administration of drug. Drug concentration in plasma was determined using High Performance Liquid Chromatography (HPLC with Fluorescence Detector. The blood concentrations versus time data were analyzed using software. Results: After single dose intravenous administration of long acting moxifloxacin the plasma concentration of 0.016 ± 0.001 μg/ml-1 was maintained for up to 72 h. Distribution half-life (t and elimination half-life (t were 1.637 ± 0.053 h, and 1/2 1/2 12.130 ± 0.202 h, following IV administration. The mean values of apparent volume of distribution V 5.436 ± 0.135 L/kg-1 d(area as well as mean residence time 10.02 ± 4.787 minute were detected with IV administration. Conclusion: The long acting Moxifloxacin @ the dose 7.5 mg/kg IV maintains the effective therapeutic concentration in the plasma of sheep for up to 72 hours. The long acting Moxifloxacin at this dose rate can be used to treat sensitive bacteria causing infectious diseases in sheep. [Vet World 2012; 5(9.000: 517-521

  9. Influence of gestational diabetes mellitus on the stereoselective kinetic disposition and metabolism of labetalol in hypertensive patients.

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    Carvalho, Teresa Maria J P; Cavalli, Ricardo de Carvalho; Cunha, Sérgio P; de Baraldi, Cláudia O; Marques, Maria P; Antunes, Natalícia J; Godoy, Ana Leonor P C; Lanchote, Vera Lucia

    2011-01-01

    This study investigated the influence of gestational diabetes mellitus on the kinetic disposition and stereoselective metabolism of labetalol administered intravenously or orally. Thirty hypertensive women during the last trimester of pregnancy were divided into four groups: non-diabetic and diabetic women treated with intravenous or oral labetalol. The pharmacokinetics of labetalol was not stereoselective in diabetic or non-diabetic pregnant women receiving the drug intravenously. However, oral administration of labetalol resulted in lower values of the area under the plasma concentration versus time curve (AUC) for the β-blocker (RR) than for the other enantiomers in both diabetic and non-diabetic women. Gestational diabetes mellitus caused changes in the kinetic disposition of the labetalol stereoisomers when administered orally. The AUC values for the less potent adrenoceptor antagonist (SS) and for the α-blocking (SR) isomers were higher in diabetic than in non-diabetic pregnant women. The approximately 100% higher AUC values obtained for the (SR) isomer in diabetic pregnant women treated with oral labetalol may be of clinical relevance in terms of the α-blocking activity of this isomer.

  10. The influence of severity of bile flow reduction, cycloheximide, and methyl isobutyl ketone pretreatment on the kinetics of taurolithocholic acid disposition in the rat.

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    Dahlström-King, L; du Souich, P; Couture, J; Plaa, G L

    1990-06-15

    Pretreatment of rats with methyl isobutyl ketone (MIBK) potentiates the effect of taurolithocholic acid (TLCA) on bile flow, while cycloheximide pretreatment diminishes the cholestatic response. Experiments were performed to determine if the effects of the pretreatments were related to changes in the kinetic disposition of TLCA. Groups of rats were pretreated daily with either 7.5 mmol MIBK/kg po for 3 days or 3.55 mumol cycloheximide/kg ip for 2 days prior to an iv challenge of TLCA. Bile and blood samples were collected for 3 hr and the blood concentrations and biliary excretion of TLCA monitored. The severity of the bile flow reduction had a marked effect on the kinetic pattern of TLCA. The volume of distribution and bile disposition constant of TLCA decreased inversely with the severity of bile flow reduction, while the blood disposition constant increased. The total clearance of TLCA was not affected, but increasing the severity of the cholestasis altered the contribution of biliary and extrabiliary clearance to total clearance. The changes in the kinetics of TLCA observed in MIBK- and cycloheximide-pretreated rats were consistent with the effects the pretreatments exerted on TLCA-induced reduction in bile flow. They were interpreted to be the result of the effects of the pretreatments rather than their cause. Thus, pretreatment with MIBK and cycloheximide appears to exert a modulating effect on TLCA-induced cholestasis by mechanisms unrelated to an alteration of TLCA kinetic profile.

  11. Disposition and kinetics of tetrabromobisphenol A in female Wistar Han rats

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    Gabriel A. Knudsen

    2014-01-01

    Full Text Available Tetrabromobisphenol A (TBBPA is the brominated flame retardant with the largest production volume worldwide. NTP 2-year bioassays found TBBPA dose-dependent increases in uterine tumors in female Wistar Han rats; evidence of reproductive tissues carcinogenicity was equivocal in male rats. To explain this apparent sex-dependence, the disposition and toxicokinetic profile of TBBPA were investigated using female Wistar Han rats, as no data were available for female rats. In these studies, the primary route of elimination following [14C]-TBBPA administration (25, 250 or 1000 mg/kg was in feces; recoveries in 72 h were 95.7 ± 3.5%, 94.3 ± 3.6% and 98.8 ± 2.2%, respectively (urine: 0.2–2%; tissues: <0.1. TBBPA was conjugated to mono-glucuronide and -sulfate metabolites and eliminated in the bile. Plasma toxicokinetic parameters for a 250 mg/kg dose were estimated based on free TBBPA, as determined by UV/radiometric-HPLC analyses. Oral dosing by gavage (250 mg/kg resulted in a rapid absorption of compound into the systemic circulation with an observed Cmax at 1.5 h post-dose followed by a prolonged terminal phase. TBBPA concentrations in plasma decreased rapidly after an IV dose (25 mg/kg followed by a long elimination phase. These results indicate low systemic bioavailability (F < 0.05, similar to previous reports using male rats. Elimination pathways appeared to become saturated leading to delayed excretion after a single oral administration of the highest dose (1000 mg/kg; no such saturation or delay was detected at lower doses. Chronic high exposures to TBBPA may result in competition for metabolism with endogenous substrates in extrahepatic tissues (e.g., SULT1E1 estrogen sulfation resulting in endocrine disruption.

  12. Disposition kinetics of selenium in healthy volunteers following therapeutic shampoo treatment.

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    Noisel, Nolwenn; Bouchard, Michèle; Carrier, Gaétan

    2010-05-01

    This study was aimed at documenting the kinetic time courses of selenium (Se) in accessible biological matrices of volunteers following controlled applications of therapeutic shampoo containing Se, to better elucidate the mechanisms by which shampoo-Se accumulates in hair and hence estimate the contribution of this source to total Se body burden. Ten healthy volunteers were exposed to Se-shampoo three times a week over a month. Blood, hair and toenail concentrations along with daily urinary excretions were repeatedly measured over an 18-month period following the onset of application. Over the entire study period, blood concentrations of Se (range: 127-233μg/l) and daily urinary excretions (range: 11.9-150μg/d) remained within baseline range of the general population. Conversely, during shampoo application, mean Se concentrations in hair reached transitional levels of 89μg/g while, following cessation of treatment, a mono-exponential decrease was observed with a mean half-life of 4.5 weeks. Two of the volunteers also exhibited an increase in toenail concentrations of Se during the study period. Results show that Se-shampoo does not contribute significantly to total Se body burden, as assessed from blood and urine levels. Differences observed between blood and urine time courses as compared to hair profiles and the presence of Se on hair grown before treatment indicates an adsorption on hair; however, the gradual decrease in Se concentrations in successive centimeters of hair grown following the application period suggests a concomitant absorption from the scalp during treatment with subsequent excretion in hair. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Disposition Kinetics of Amoxicillin in Healthy, Hepatopathic and Nephropathic Conditions in Chicken after Single Oral Administration

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    Moloy Kumar Bhar

    2010-12-01

    Full Text Available Fifteen broiler chickens (COBB 400 of 42 days of age weighing 1.8 to 2.0 kg were equally divided into 3 groups, each consisting of 5 birds. Hepatopathy was induced by oral administration of paracetamol while nephropathy was induced by intravenous administration of uranyl nitrate. Kinetic study was investigated in healthy, hepatopathic and nephropathic birds following single oral administration of amoxicillin at 40 mg kg-1. Blood samples were collected at different time schedule. Plasma concentrations of amoxicillin in healthy, hepatopathic and nephropathic birds were 41.90 ± 5.59, 9.93 ± 0.76 and 38.75 ± 6.08 µg ml-1, respectively at 1 hr; 15.34 ± 1.99, 18.57 ± 1.66 and 67.40 ± 2.62 µg ml-1, respectively at 4 hr and 2.03 ± 0.28, 15.54 ± 0.82 and 30.63 ± 1.58 µg ml-1, respectively at 24 hr. Maximum plasma concentration was detected at 1 hr in healthy birds (41.90 ± 5.59 µg ml-1 , at 8 hr in hepatopathic birds (23.51 ± 1.64 µg ml-1 and at 4 hr in nephropathic birds (67.40 ± 2.62 µg ml-1. The drug could not be detected in plasma beyond 24 hr in healthy, 72 hr in both hepatopathic and nephropathic birds. The concentration of amoxicillin was significantly (P < 0.01 higher in most of the samples of hepatopathic and nephropathic birds compared to healthy birds. Significant higher values (P < 0.01 of t1/2 K, AUC, and MRT and lower values of K and ClB in the hepatopathic and nephropathic birds in comparison to healthy birds were observed.

  14. Dispositional logic

    Energy Technology Data Exchange (ETDEWEB)

    Zadeh, L.A.

    1988-01-01

    The applicability of conventional mathematical analysis (based on the combination of two-valued logic and probability theory) to problems in which human judgment, perception, or emotions play significant roles is considered theoretically. It is shown that dispositional logic, a branch of fuzzy logic, has particular relevance to the common-sense reasoning typical of human decision-making. The concepts of dispositionality and usuality are defined analytically, and a dispositional conjunctive rule and dispositional modus ponens are derived. 7 references.

  15. Representing dispositions

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    Röhl Johannes

    2011-08-01

    Full Text Available Abstract Dispositions and tendencies feature significantly in the biomedical domain and therefore in representations of knowledge of that domain. They are not only important for specific applications like an infectious disease ontology, but also as part of a general strategy for modelling knowledge about molecular interactions. But the task of representing dispositions in some formal ontological systems is fraught with several problems, which are partly due to the fact that Description Logics can only deal well with binary relations. The paper will discuss some of the results of the philosophical debate about dispositions, in order to see whether the formal relations needed to represent dispositions can be broken down to binary relations. Finally, we will discuss problems arising from the possibility of the absence of realizations, of multi-track or multi-trigger dispositions and offer suggestions on how to deal with them.

  16. Foucaults Dispositive

    DEFF Research Database (Denmark)

    Raffnsøe, Sverre; Gudmand-Høyer, Marius T.; Thaning, Morten Sørensen

    2016-01-01

    While Foucault’s work has had a crucial impact on organizational research, the analytical potential of the dispositive has not been sufficiently developed. The purpose of this article is to reconstruct the notion of the dispositive as a key conception in Foucault’s thought, particularly in his...... lectures at the Collège de France, and to develop dispositional analytics with specific reference to matters of organization. Foucault’s dispositional analysis articulates a history of interrelated social technologies that have been constructed to organize how we relate to each other. The article...... contribute to a more complex understanding of organizational dynamics, power, strategy, resistance, and critique. Dispositional analytics allows for a new interpretation and use of Foucault in relation to organization studies....

  17. Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity.

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    Benowitz, Neal L; St Helen, Gideon; Dempsey, Delia A; Jacob, Peyton; Tyndale, Rachel F

    2016-07-01

    The rate of nicotine metabolism, determined primarily by CYP2A6 activity, influences tobacco dependence and smoking-induced disease risk. The prevalence of CYP2A6 gene variants differs by race, with greater numbers in African Americans compared with Caucasians. We studied nicotine disposition kinetics and metabolism by the CYP2A6 genotype and enzymatic activity, as measured by the nicotine metabolite ratio (NMR), in African American smokers. Participants were administered intravenous infusions of deuterium-labeled nicotine and cotinine. Plasma and urine concentrations of nicotine and metabolites were measured and pharmacokinetic parameters were estimated. Pharmacokinetic parameters and urine metabolite excretion data were analyzed by CYP2A6 genotype and by NMR. A number of gene variants were associated with markedly reduced nicotine and cotinine clearances. NMR was strongly correlated with nicotine (r=0.72) and cotinine (r=0.80) clearances. Participants with higher NMR excreted significantly greater nicotine C-oxidation and lower non-C-oxidation products compared with lower NMR participants. CYP2A6 genotype, NMR, and nicotine pharmacokinetic data may inform studies of individual differences in smoking behavior and biomarkers of nicotine exposure.

  18. Dispositional greed.

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    Seuntjens, Terri G; Zeelenberg, Marcel; van de Ven, Niels; Breugelmans, Seger M

    2015-06-01

    Greed is an important motive: it is seen as both productive (a source of ambition; the motor of the economy) and destructive (undermining social relationships; the cause of the late 2000s financial crisis). However, relatively little is known about what greed is and does. This article reports on 5 studies that develop and test the 7-item Dispositional Greed Scale (DGS). Study 1 (including 4 separate samples from 2 different countries, total N = 6092) provides evidence for the construct and discriminant validity of the DGS in terms of positive correlations with maximization, self-interest, envy, materialism, and impulsiveness, and negative correlations with self-control and life satisfaction. Study 2 (N = 290) presents further evidence for discriminant validity, finding that the DGS predicts greedy behavioral tendencies over and above materialism. Furthermore, the DGS predicts economic behavior: greedy people allocate more money to themselves in dictator games (Study 3, N = 300) and ultimatum games (Study 4, N = 603), and take more in a resource dilemma (Study 5, N = 305). These findings shed light on what greed is and does, how people differ in greed, and how greed can be measured. In addition, they show the importance of greed in economic behavior and provide directions for future studies. (c) 2015 APA, all rights reserved).

  19. kinetics

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    D. E. Panayotounakos

    2002-01-01

    Full Text Available We present the construction of the general solutions concerning the one-dimensional (1D fully dynamic nonlinear partial differential equations (PDEs, for the erosion kinetics. After an uncoupling procedure of the above mentioned equations a second–order nonlinear PDE of the Monge type governing the porosity is derived, the general solution of which is constructed in the sense that a full complement of arbitrary functions (as many as the order is introduced. Afterwards, we specify the above solution according to convenient initial conditions.

  20. What is a Dispositive?

    DEFF Research Database (Denmark)

    Raffnsøe, Sverre; Gudmand-Høyer, Marius T.; Thaning, Morten Sørensen

    This article advances the ‘dispositive’ (le dispositif) as a key conception in Foucault’s work. As developed in his annual lectures in 1978 and 1979, the dispositive represents a crucial constituent of societal analysis on par with the familiar analytics of power/knowledge and the governmentality...... perspective – indeed it forms a lesser known intermediary between these. Foucault’s dispositional analysis articulates a history of connected social technologies that we have constructed to relate to each other. Expounding these points, the article distinguishes various dispositional prototypes and develops...... key ‘socio-ontological’ implications of the analy-sis. Reinstating the proper analytical status of the dispositive contributes to the reception of the important notion; the interpretation of Foucault’s entire oeuvre; and a resourceful approach to the study of contemporary societal problems....

  1. Leadership: Dispositional and Situational. Revision

    Science.gov (United States)

    1988-11-01

    block number) For over four decades, leadership research has examined the issue of whether internal dispositions ( traits ), situational characteristics... leadership research has examined the issue of whether internal dispositions ( traits ), situational characteristics (contexts), or some combination of...Situational 3 Leadership : Dispositional and Situational The person-situation debate has been a key issue in several areas of psychology and management

  2. Five Dispositions for Personalization

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    Carter, Kim

    2017-01-01

    The author reviews various ways personalized learning has come to be interpreted and asserts that rather than requiring we create individualized learning plans for each student, true personalization requires that teachers give learners the tools, knowledge, skills, and dispositions to manage themselves and their learning environment. Teachers…

  3. FS65 Disposition Option Report

    Energy Technology Data Exchange (ETDEWEB)

    Wenz, Tracy R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-09-25

    This report outlines the options for dispositioning the MOX fuel stored in FS65 containers at LANL. Additional discussion regarding the support equipment for loading and unloading the FS65 transport containers is included at the end of the report.

  4. FAILED FUEL DISPOSITION STUDY

    Energy Technology Data Exchange (ETDEWEB)

    THIELGES, J.R.

    2004-12-20

    In May 2004 alpha contamination was found on the lid of the pre-filter housing in the Sodium Removal Ion Exchange System during routine filter change. Subsequent investigation determined that the alpha contamination likely came from a fuel pin(s) contained in an Ident-69 (ID-69) type pin storage container serial number 9 (ID-69-9) that was washed in the Sodium Removal System (SRS) in January 2004. Because all evidence indicated that the wash water interacted with the fuel, this ID49 is designated as containing a failed fuel pin with gross cladding defect and was set aside in the Interim Examination and Maintenance (IEM) Cell until it could be determined how to proceed for long term dry storage of the fuel pin container. This ID49 contained fuel pins from the driver fuel assembly (DFA) 16392, which was identified as a Delayed Neutron Monitor (DNM) leaker assembly. However, this DFA was disassembled and the fuel pin that was thought to be the failed pin was encapsulated and was not located in this ID49 container. This failed fuel disposition study discusses two alternatives that could be used to address long term storage for the contents of ID-69-9. The first alternative evaluated utilizes the current method of identifying and storing DNM leaker fuel pin(s) in tubes and thus, verifying that the alpha contamination found in the SRS came from a failed pin in this pin container. This approach will require unloading selected fuel pins from the ID-69, visually examining and possibly weighing suspect fuel pins to identify the failed pin(s), inserting the failed pin(s) in storage tubes, and reloading the fuel pins into ID49 containers. Safety analysis must be performed to revise the 200 Area Interim Storage Area (ISA) Final Safety Analysis Report (FSAR) (Reference 1) for this fuel configuration. The second alternative considered is to store the failed fuel as-is in the ID-69. This was evaluated to determine if this approach would comply with storage requirements. This

  5. 39 CFR 954.3 - Informal dispositions.

    Science.gov (United States)

    2010-07-01

    ..., SUSPENSION, OR REVOCATION OF PERIODICALS MAIL PRIVILEGES § 954.3 Informal dispositions. These rules do not preclude the informal dispositions of Periodicals mailing privilege matters before or after institution of...

  6. Happiness, Dispositions and the Self

    DEFF Research Database (Denmark)

    Klausen, Søren Harnow

    2016-01-01

    I argue that happiness is an exclusively categorical mental state. Daniel Haybron’s inclusion of dispositions into his emotional state theory rests of a confusion of constituents of happiness in the narrow psychological sense with objects of prudential concern, to which obviously belong “mood...... propensities” and other dispositional states. I further argue that while it is probably correct to require of a constituent of happiness that it must in some sense be “deep” and belong to, or directly impact on, a persons’ self, the importance of depth may be overrated by the emotional state theory, which also...

  7. Social Justice and Dispositions for Adult Education

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    Holst, John D.

    2010-01-01

    The article identifies dispositions from a thematic investigation of the pedagogical practice of Ernesto Che Guevara and various social movements in the United States. The article outlines and places these dispositions within the context of debates over social justice and dispositions for education program accreditation in the United States that…

  8. The role of dispositions in explanations

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    Agustín VICENTE

    2010-01-01

    Full Text Available According to a model defended by some authors, dispositional concepts can be legitimately used in causal explanations, although such a use is not necessary. I argue, however, that there is a kind of use of dispositions in explanations that does not fall within this model: we will miss some explanations if we forsake dispositional concepts and explanations.

  9. A disposition of interpolation techniques

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    Knotters, M.; Heuvelink, G.B.M.

    2010-01-01

    A large collection of interpolation techniques is available for application in environmental research. To help environmental scientists in choosing an appropriate technique a disposition is made, based on 1) applicability in space, time and space-time, 2) quantification of accuracy of interpolated

  10. Signs, dispositions, and semiotic scaffolding.

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    Fernández, Eliseo

    2015-12-01

    In theoretical work we distinguish living beings from inanimate objects on the basis of some paramount attributes, such as agency and autonomy. These abstract features are not directly accessible to our scrutiny, but we surmise their nature through observation of the purpose-oriented behavior of organisms. I intend to show that organismal purposefulness springs from the intrinsic, constitutive kind of finality that is the hallmark of all semiotic transactions. To this aim I develop a dispositionalist account of organismal causation based on a distinction between two kinds of causal dispositions: fixed (efficient) dispositions and traveling dispositions. Fixed dispositions are rigidly attached to physical structures and processes; these are the dispositions regularly invoked in current discussions of causal explanation. Traveling dispositions are able to move freely from one location to another by becoming embodied into suitable supporting media. I introduce these notions to articulate a view of semiosis I deem best suited to the life sciences, and contend that sign tokens are vehicles of traveling dispositions. This account places the origin of purposive behavior at the interaction of physical and semiotic causation. To properly motivate the discussion I briefly review some recent developments in the philosophy of science concerning various forms of causation invoked by scientists across disciplines to frame explanations and make predictions. The ensuing discussion gives particular prominence to mechanistic (as distinct from mechanicist) explanatory accounts of biological phenomena. This review is followed by a brief characterization of a "nomological machine," a comprehensive schema introduced and developed by Nancy Cartwright with the goal of explaining causal mechanisms in a general setting. By capitalizing on this model's heuristic virtues I seek to formulate a compelling view of the interactions between physical and semiotic causation at play in semiotic

  11. Linguistic variables, approximate reasoning and dispositions

    Energy Technology Data Exchange (ETDEWEB)

    Zadeh, L.A.

    1983-07-01

    Test-score semantics is applied to the representation of meaning of dispositions, that is, propositions with suppressed fuzzy quantifiers, e.g. overeating causes obesity, icy roads are slippery, young men like young women, etc. The concept of a disposition plays an especially important role in the representation of commonsense knowledge. 45 references.

  12. Overview of surplus weapons plutonium disposition

    Energy Technology Data Exchange (ETDEWEB)

    Rudy, G.

    1996-05-01

    The safe disposition of surplus weapons useable plutonium is a very important and urgent task. While the functions of long term storage and disposition directly relate to the Department`s weapons program and the environmental management program, the focus of this effort is particularly national security and nonproliferation.

  13. Dispositions in Education: Nonentities Worth Talking about

    Science.gov (United States)

    Splitter, Laurance J.

    2010-01-01

    The concept of dispositions has commanded considerable attention in both philosophy and education. In this essay, Laurance Splitter draws on philosophy to take a fresh look at dispositions in education, specifically teacher education. Bypassing the pitfalls of both subjectivity and crude behaviorism, he proposes a conceptual framework in which…

  14. 7 CFR 1000.3 - Route disposition.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Definitions § 1000.3 Route disposition. Route disposition means a delivery to a retail or wholesale outlet...

  15. Critical Thinking Dispositions in Online Nursing Education

    Science.gov (United States)

    Carter, Lorraine Mary

    2008-01-01

    As part of a doctoral study, the critical thinking dispositions of post-RN (post-diploma) nurses continuing their education at a mid-sized university were measured before and after the intervention of a three-credit online course. The tool used to measure the changes in critical thinking disposition was the California Critical Thinking…

  16. Accuracy of rapid disposition by emergency clinicians.

    Science.gov (United States)

    Backay, Andrew; Bystrzycki, Adam; Smit, De Villiers; Keogh, Martin; O'Reilly, Gerard; Mitra, Biswadev

    2017-05-01

    Objectives Rapid disposition protocols are increasingly being considered for implementation in emergency departments (EDs). Among patients presenting to an adult tertiary referral hospital, this study aimed to compare prediction accuracy of a rapid disposition decision at the conclusion of history and examination, compared with disposition following standard assessment. Methods Prospective observational data were collected for 1 month between October and November 2012. Emergency clinicians (including physicians, registrars, hospital medical officers, interns and nurse practitioners) filled out a questionnaire within 5min of obtaining a history and clinical examination for eligible patients. Predicted patient disposition (representing 'rapid disposition') was compared with final disposition (determined by 'standard assessment'). Results There were 301 patient episodes included in the study. Predicted disposition was correct in 249 (82.7%, 95% confidence interval (CI) 78.0-86.8) cases. Accuracy of predicting discharge to home appeared highest among emergency physicians at 95.8% (95% CI 78.9-99.9). Overall accuracy at predicting admission was 79.7% (95% CI 67.2-89.0). The remaining 20.3% (95% CI 11.0-32.8) were not admitted following standard assessment. Conclusion Rapid disposition by ED clinicians can predict patient destination accurately but was associated with a potential increase in admission rates. Any model of care using rapid disposition decision making should involve establishment of inpatient systems for further assessment, and a culture of timely inpatient team transfer of patients to the most appropriate treating team for ongoing patient management. What is known about the topic? In response to the National Emergency Access Targets, there has been widespread adoption of rapid-disposition-themed care models across Australia. Although there is emerging data that clinicians can predict disposition accurately, this data is currently limited. What does this

  17. ESTIMATING IMPURITIES IN SURPLUS PLUTONIUM FOR DISPOSITION

    Energy Technology Data Exchange (ETDEWEB)

    Allender, J.; Moore, E.

    2013-07-17

    The United States holds at least 61.5 metric tons (MT) of plutonium that is permanently excess to use in nuclear weapons programs, including 47.2 MT of weapons-grade plutonium. Surplus inventories will be stored safely by the Department of Energy (DOE) and then transferred to facilities that will prepare the plutonium for permanent disposition. The Savannah River National Laboratory (SRNL) operates a Feed Characterization program for the Office of Fissile Materials Disposition of the National Nuclear Security Administration and the DOE Office of Environmental Management. Many of the items that require disposition are only partially characterized, and SRNL uses a variety of techniques to predict the isotopic and chemical properties that are important for processing through the Mixed Oxide Fuel Fabrication Facility and alternative disposition paths. Recent advances in laboratory tools, including Prompt Gamma Analysis and Peroxide Fusion treatment, provide data on the existing inventories that will enable disposition without additional, costly sampling and destructive analysis.

  18. Tissue disposition of bifenthrin in the rat

    Data.gov (United States)

    U.S. Environmental Protection Agency — Tissue disposition of bifenthrin in the rat and oral and intravenous administration. This dataset is associated with the following publication: Hughes , M., D. Ross...

  19. Dispositional affectivity and work outcomes of expatriates

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2013-01-01

    How the two components of dispositional affectivity, positive affectivity, representing the predisposition to respond positively to environmental stimuli, and negative affectivity, depicting the opposite reaction, influence work has been the focus of much research. Although dispositional...... affectivity appears to be a promising construct to explain and predict many attitudinal and behavioral outcomes in the workplace, few studies have empirically investigated dispositional affectivity and the work of expatriates. Hence, data from a net-based survey including 350 expatriates in Denmark were used...... to examine the relationship between dispositional affectivity and their work outcomes. Results showed consistent positive associations between positive affectivity and all the studied work outcomes and the opposite relationships for negative affectivity. Implications and suggestions for future research...

  20. Demographic and dispositional characteristics as predictors of ...

    African Journals Online (AJOL)

    Demographic and dispositional characteristics as predictors of organisational citizenship behaviour. ... as important predictors of OCB. The study identified some future directions for personality research in industrial, work, and organizational psychology and concludes with some caveats and directions for future research.

  1. KE Basin water dispositioning engineering study

    Energy Technology Data Exchange (ETDEWEB)

    Hunacek, G.S.; Gahir, S.S.

    1994-09-23

    This engineering study is a feasibility study of KE Basin water treatment to an acceptable level and dispositioning the treated water to Columbia River, ground through ETF or to air through evaporation.

  2. Excess plutonium disposition using ALWR technology

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, A. (ed.); Buckner, M.R.; Radder, J.A.; Angelos, J.G.; Inhaber, H.

    1993-02-01

    The Office of Nuclear Energy of the Department of Energy chartered the Plutonium Disposition Task Force in August 1992. The Task Force was created to assess the range of practicable means of disposition of excess weapons-grade plutonium. Within the Task Force, working groups were formed to consider: (1) storage, (2) disposal,and(3) fission options for this disposition,and a separate group to evaluate nonproliferation concerns of each of the alternatives. As a member of the Fission Working Group, the Savannah River Technology Center acted as a sponsor for light water reactor (LWR) technology. The information contained in this report details the submittal that was made to the Fission Working Group of the technical assessment of LWR technology for plutonium disposition. The following aspects were considered: (1) proliferation issues, (2) technical feasibility, (3) technical availability, (4) economics, (5) regulatory issues, and (6) political acceptance.

  3. Foundational skills and dispositions for learning

    DEFF Research Database (Denmark)

    Caviglia, Francesco; Delfino, Manuela

    2016-01-01

    the development of more general learning dispositions and competences. After a period of training with IPS activities, the experimental group showed different dispositions towards learning from a text and engaging with open-ended questions. Despite serious limitations in the depth of analysis, most students were...... able to reach acceptable solutions; at the same time, they felt empowered and developed an embryonic critical attitude on which it might be possible to build further....

  4. The return of dispositionalism: On the linguistic consequences of dispositional suppression

    NARCIS (Netherlands)

    Geeraert, N.; Yzerbyt, V.Y.; Corneille, O.; Wigboldus, D.H.J.

    2004-01-01

    Yzerbyt, Corneille, Dumont, and Hahn (2001) showed that the correction of dispositional inferences does not only involve a close examination of situational constraints but also the suppression of those dispositional inferences. Building on the literature of mental control ( Wegner, 1994; Wenzlaff &

  5. Validity Issues in Assessing Dispositions: The Confirmatory Factor Analysis of a Teacher Dispositions Form

    Science.gov (United States)

    Niu, Chunling; Everson, Kimberlee; Dietrich, Sylvia; Zippay, Cassie

    2017-01-01

    Critics against the inclusion of dispositions as part of the teacher education accreditation focus on the dearth of empirical literature on reliably and validly accessing dispositions (Borko, Liston, & Whitcomb, 2007). In this study, a confirmatory factor analysis (CFA) was performed to test the factorial validity of a teacher dispositions…

  6. Dispositional optimism and loneliness in older men.

    Science.gov (United States)

    Rius-Ottenheim, Nathaly; Kromhout, Daan; van der Mast, Roos C; Zitman, Frans G; Geleijnse, Johanna M; Giltay, Erik J

    2012-02-01

    Dispositional optimism, defined as a generalized tendency to positive outcome expectancies, is associated with well-being and successful aging. However, it remains unclear whether optimism is also correlated to less feelings of loneliness over time. We aimed to determine whether dispositional optimism is prospectively associated with less feelings of loneliness, independently of potential confounders inherent to the aging process. We observed 416 older men aged between 70 and 89 years (mean 74.9 years, standard deviation [SD] 4.7 years) within the population-based Zutphen Elderly Study during 10 years of follow-up. Baseline dispositional optimism was assessed using a four-item questionnaire. The presence of feelings of loneliness, the main outcome of our study, was assessed using the 11-item loneliness scale of De Jong Gierveld in the years 1990, 1993, 1995, and 2000. The association between baseline dispositional optimism and loneliness over time was tested by using multilevel regression analysis and by adjusting for potential confounders (i.e. age, living arrangement, social contacts, widowhood, memberships, self-rated health, and depressive symptoms). Feelings of loneliness significantly increased during 10 years of follow-up but showed temporal stability (reliability coefficient 0.78). Low baseline dispositional optimism was strongly associated with loneliness over time, also in the adjusted analysis. A 1 SD increase in baseline dispositional optimism was associated with a 0.14 SD (95% confidence interval 0.04-0.23) lower level of loneliness (F(1,320)  = 7.8; p = 0.006). Dispositional optimism is correlated to lower feelings of loneliness over time in older men, independently of depression or changes in social network. Copyright © 2011 John Wiley & Sons, Ltd.

  7. NRC comprehensive records disposition schedule. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    Title 44 US Code, ``Public Printing and Documents,`` regulations issued by the General Service Administration (GSA) in 41 CFR Chapter 101, Subchapter B, ``Management and Use of Information and Records,`` and regulations issued by the National Archives and Records Administration (NARA) in 36 CFR Chapter 12, Subchapter B, ``Records Management,`` require each agency to prepare and issue a comprehensive records disposition schedule that contains the NARA approved records disposition schedules for records unique to the agency and contains the NARA`s General Records Schedules for records common to several or all agencies. The approved records disposition schedules specify the appropriate duration of retention and the final disposition for records created or maintained by the NRC. NUREG-0910, Rev. 3, contains ``NRC`s Comprehensive Records Disposition Schedule,`` and the original authorized approved citation numbers issued by NARA. Rev. 3 incorporates NARA approved changes and additions to the NRC schedules that have been implemented since the last revision dated March, 1992, reflects recent organizational changes implemented at the NRC, and includes the latest version of NARA`s General Records Schedule (dated August 1995).

  8. Kinetic Typography

    DEFF Research Database (Denmark)

    van Leeuwen, Theo; Djonov, Emilia

    2014-01-01

    After discussing broad cultural drivers behind the development of kinetic typography, the chapter outlines an approach to analysing kinetic typography which is based on Halliday's theory of transitivity, as applied by Kress and Van Leeuwen to visual images....

  9. Dispositional optimism and coping with pain

    Directory of Open Access Journals (Sweden)

    Bargiel-Matusiewicz K

    2009-12-01

    Full Text Available Abstract Objective The aim of this article is to analyze the relation between dispositional optimism and coping with chronic pain. The study seeks to define the relation between life orientation (optimism vs. pessimism and coping with pain (believes about pain control and the choice of coping strategy. Material and methods The following questionnaires were used: LOT-R - Life Orientation Test, BPCQ - The Beliefs about Pain Control Questionnaire and CSQ - The Pain Coping Strategies Questionnaire. Results The results show that dispositional optimism correlates positively with: internal locus of pain control r = 0.6, P Conclusions We conclude that dispositional optimism plays a key role in forming the mechanisms of coping with chronic pain and thereby in improving the psychophysical comfort of patients.

  10. From Dispositions to Behaviors: The Flip Side of Attribution.

    Science.gov (United States)

    Reeder, Glenn D.; And Others

    1982-01-01

    Investigated the implicational relations between dispositional levels and relevant categories of behavior. Findings were consistent with the idea that dispositional labels are used to represent a central tendency in a person's behavior. (Author)

  11. 78 FR 57547 - Guidance Regarding Dispositions of Tangible Depreciable Property

    Science.gov (United States)

    2013-09-19

    ... document contains proposed regulations regarding dispositions of property subject to depreciation under...) regarding the accounting for, and dispositions of, property subject to depreciation under section 168 (MACRS... provide rules for establishing general asset accounts, for computing depreciation for general asset...

  12. 12 CFR 34.83 - Disposition of real estate.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Disposition of real estate. 34.83 Section 34.83 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY REAL ESTATE LENDING AND APPRAISALS Other Real Estate Owned § 34.83 Disposition of real estate. (a) Disposition. A national bank may...

  13. 50 CFR 30.2 - Disposition of surplus range animals.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Disposition of surplus range animals. 30.2... (CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM RANGE AND FERAL ANIMAL MANAGEMENT Range Animals § 30.2 Disposition of surplus range animals. Disposition shall be made only during regularly scheduled disposal...

  14. Revisiting Disposition Assessment in Teacher Education: Broadening the Focus

    Science.gov (United States)

    Jung, Eunjoo; Rhodes, Dent M.

    2008-01-01

    Today's teacher education programmes across the world strive to equip future teachers with the high-quality knowledge, skills and dispositions necessary to teach students. The assessment of teacher dispositions has thus become essential to cultivate those qualities. However, the current approach to disposition assessment in the United States…

  15. 27 CFR 70.184 - Disposition of perishable goods.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Disposition of perishable goods. 70.184 Section 70.184 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Collection of Excise and Special (Occupational) Tax Disposition of Property § 70.184 Disposition of...

  16. Dispositional optimism and loneliness in older men

    NARCIS (Netherlands)

    Rius-Ottenheim, N.; Kromhout, D.; Mast, van der R.C.; Zitman, F.G.; Geleijnse, J.M.; Giltay, E.J.

    2012-01-01

    Background: Dispositional optimism, defined as a generalized tendency to positive outcome expectancies, is associated with well-being and successful aging. However, it remains unclear whether optimism is also correlated to less feelings of loneliness over time. We aimed to determine whether

  17. Dispositional Mindfulness, Meditation, and Conditional Goal Setting.

    Science.gov (United States)

    Crane, Catherine; Jandric, Danka; Barnhofer, Thorsten; Williams, J Mark G

    2010-12-01

    Conditional goal setting (CGS, the tendency to regard high order goals such as happiness, as conditional upon the achievement of lower order goals) is observed in individuals with depression and recent research has suggested a link between levels of dispositional mindfulness and conditional goal setting in depressed patients. Since interventions which aim to increase mindfulness through training in meditation are used with patients suffering from depression it is of interest to examine whether such interventions might alter CGS. Study 1 examined the correlation between changes in dispositional mindfulness and changes in CGS over a 3-4 month period in patients participating in a pilot randomised controlled trial of Mindfulness-Based Cognitive Therapy (MBCT). Results indicated that increases in dispositional mindfulness were significantly associated with decreases in CGS, although this effect could not be attributed specifically to the group who had received training in meditation. Study 2 explored the impact of brief periods of either breathing or loving kindness meditation on CGS in 55 healthy participants. Contrary to expectation, a brief period of meditation increased CGS. Further analyses indicated that this effect was restricted to participants low in goal re-engagement ability who were allocated to loving kindness meditation. Longer term changes in dispositional mindfulness are associated with reductions in CGS in patients with depressed mood. However initial reactions to meditation, and in particular loving kindness meditation, may be counterintuitive and further research is required in order to determine the relationship between initial reactions and longer-term benefits of meditation practice.

  18. 7 CFR 1033.3 - Route disposition.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Route disposition. 1033.3 Section 1033.3 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating...

  19. The mind as skills and dispositions

    DEFF Research Database (Denmark)

    Brinkmann, Svend

    2012-01-01

    to broaden Harré’s hybrid psychology by including not just the brain, but also the body, social practices, and technological artifacts as mediators of the mind. The mind is understood not as a substance of any kind, but as a set of skills and dispositions to act, think, and feel. This implies a normative...

  20. Critical Dispositions: Evidence and Expertise in Education

    Science.gov (United States)

    Dimitriadis, Greg

    2011-01-01

    Set against the current proliferation of global "difference" and economic realignment, "Critical Dispositions" explores the notions of "evidence" and "expertise" in times of material scarcity. Both have come to the forefront of national and international debate in education as "evidence" and "evidence-based" research and pedagogical practices…

  1. Women Faculty, Professional Identity, and Generational Disposition

    Science.gov (United States)

    Marine, Susan B.; Martínez Alemán, Ana M.

    2018-01-01

    In an exploratory qualitative study, the generational dispositions of tenured women faculty from the Boomer Generation were examined. As pioneers and now senior members in the academic profession in the Golden Era of American higher education, they exist in a common historical location characterized by cultural forces and events that helped to…

  2. Critical thinking dispositions among newly graduated nurses

    Science.gov (United States)

    Wangensteen, Sigrid; Johansson, Inger S; Björkström, Monica E; Nordström, Gun

    2010-01-01

    wangensteen s., johansson i.s., björkström m.e. & nordström g. (2010) Critical thinking dispositions among newly graduated nurses. Journal of Advanced Nursing66(10), 2170–2181. Aim The aim of the study was to describe critical thinking dispositions among newly graduated nurses in Norway, and to study whether background data had any impact on critical thinking dispositions. Background Competence in critical thinking is one of the expectations of nursing education. Critical thinkers are described as well-informed, inquisitive, open-minded and orderly in complex matters. Critical thinking competence has thus been designated as an outcome for judging the quality of nursing education programmes and for the development of clinical judgement. The ability to think critically is also described as reducing the research–practice gap and fostering evidence-based nursing. Methods A cross-sectional descriptive study was performed. The data were collected between October 2006 and April 2007 using the California Critical Thinking Disposition Inventory. The response rate was 33% (n= 618). Pearson’s chi-square tests were used to analyse the data. Results Nearly 80% of the respondents reported a positive disposition towards critical thinking. The highest mean score was on the Inquisitiveness subscale and the lowest on the Truth-seeking subscale. A statistically significant higher proportion of nurses with high critical thinking scores were found among those older than 30 years, those with university education prior to nursing education, and those working in community health care. Conclusion Nurse leaders and nurse teachers should encourage and nurture critical thinking among newly graduated nurses and nursing students. The low Truth-seeking scores found may be a result of traditional teaching strategies in nursing education and might indicate a need for more student-active learning models. PMID:20384637

  3. Disposition of amopyroquin in rats and rabbits and in vitro activity against Plasmodium falciparum.

    OpenAIRE

    Pussard, E; Verdier, F; Faurisson, F; Clavier, F; Simon, F.; Gaudebout, C

    1988-01-01

    The disposition of amopyroquin was studied in rats after a single 50-mg/kg (body weight) oral dose of amopyroquin base. After a rapid absorption phase, the drug concentrations decreased in the plasma, with a terminal half-life of 14.5 h. The drug was widely distributed in the liver and lungs and, to a lesser extent, in the kidneys and spleen. In rabbits, the kinetic parameters were compared after a single 10-mg/kg dose of amopyroquin base through intravenous, intramuscular (i.m.), and oral ro...

  4. Dispositions and changing teacher practice in mathematics

    DEFF Research Database (Denmark)

    Meaney, Tamsin; Lange, Troels; Valero, Paola

    2009-01-01

    classrooms, little is known about how teachers perceive factors interacting together to affect student learning outcomes. What is known is that large-scale professional development programmes can lead to increases, rather than decreases, in differences in achievement between student groups based on ethnicity......). The complexity of factors that influence the actions of learners is described as a learning landscape (Alrø, Skovsmose & Valero, 2009). Different interrelated dimensions constitute this complex network of social practices (Valero, 2007). Kemmis and Grootenboer (2008), using a scheme from Aristotle and adopted...... (2008) provided more details about how dispositions are shaped by factors external to the individual. They described three extra-individual structures and processes - culturally-discursive, material-economic and social-political - that"shape dispositions and actions, both in the educator's general...

  5. Dispositional optimism and coping with pain

    OpenAIRE

    Bargiel-Matusiewicz, K; Krzyszkowska, A

    2009-01-01

    Abstract Objective The aim of this article is to analyze the relation between dispositional optimism and coping with chronic pain. The study seeks to define the relation between life orientation (optimism vs. pessimism) and coping with pain (believes about pain control and the choice of coping strategy). Material and methods The following questionnaires were used: LOT-R - Life Orientation Test, BPCQ - The Beliefs about Pain Control Questionnaire and CSQ - The Pain Coping Strategies Questionna...

  6. The ultimate disposition of depleted uranium

    Energy Technology Data Exchange (ETDEWEB)

    Lemons, T.R. [Uranium Enrichment Organization, Oak Ridge, TN (United States)

    1991-12-31

    Depleted uranium (DU) is produced as a by-product of the uranium enrichment process. Over 340,000 MTU of DU in the form of UF{sub 6} have been accumulated at the US government gaseous diffusion plants and the stockpile continues to grow. An overview of issues and objectives associated with the inventory management and the ultimate disposition of this material is presented.

  7. DISPOSITION EFFECT AMONG BRAZILIAN EQUITY FUND MANAGERS

    Directory of Open Access Journals (Sweden)

    Eduardo Pozzi Lucchesi

    2015-01-01

    Full Text Available The disposition effect predicts that investors tend to sell winning stocks too soon and ride losing stocks too long. Despite the wide range of research evidence about this issue, the reasons that lead investors to act this way are still subject to much controversy between rational and behavioral explanations. In this article, the main goal was to test two competing behavioral motivations to justify the disposition effect: prospect theory and mean reversion bias. To achieve it, an analysis of monthly transactions for a sample of 51 Brazilian equity funds from 2002 to 2008 was conducted and regression models with qualitative dependent variables were estimated in order to set the probability of a manager to realize a capital gain or loss as a function of the stock return. The results brought evidence that prospect theory seems to guide the decision-making process of the managers, but the hypothesis that the disposition effect is due to mean reversion bias could not be confirmed.

  8. Situational coping and coping dispositions in a stressful transaction.

    Science.gov (United States)

    Carver, C S; Scheier, M F

    1994-01-01

    After reporting dispositional coping styles, students reported situational coping and 4 classes of affect (from threat, challenge, harm, and benefit appraisals) 2 days before an exam, after the exam but before grades were posted, and after posting of grades. Coping did not predict lower levels of future distress; indeed, some coping seemed to induce feelings of threat. Feelings of harm before the exam induced several kinds of coping after the exam, mostly dysfunctional. Confidence about one's grade was a better predictor of emotions throughout than was coping. Dispositional coping predicted comparable situational coping at low-moderate levels in most cases. Coping dispositions did not reliably predict emotions, however, with these exceptions: Dispositional denial was related to threat, as was dispositional use of social support; dispositional use of alcohol was related to both threat and harm.

  9. Kinetic Interface

    DEFF Research Database (Denmark)

    2009-01-01

    A kinetic interface for orientation detection in a video training system is disclosed. The interface includes a balance platform instrumented with inertial motion sensors. The interface engages a participant's sense of balance in training exercises.......A kinetic interface for orientation detection in a video training system is disclosed. The interface includes a balance platform instrumented with inertial motion sensors. The interface engages a participant's sense of balance in training exercises....

  10. Dispositional Optimism and Therapeutic Expectations in Early Phase Oncology Trials

    Science.gov (United States)

    Jansen, Lynn A.; Mahadevan, Daruka; Appelbaum, Paul S.; Klein, William MP; Weinstein, Neil D.; Mori, Motomi; Daffé, Racky; Sulmasy, Daniel P.

    2016-01-01

    Purpose Prior research has identified unrealistic optimism as a bias that might impair informed consent among patient-subjects in early phase oncology trials. Optimism, however, is not a unitary construct – it can also be defined as a general disposition, or what is called dispositional optimism. We assessed whether dispositional optimism would be related to high expectations for personal therapeutic benefit reported by patient-subjects in these trials but not to the therapeutic misconception. We also assessed how dispositional optimism related to unrealistic optimism. Methods Patient-subjects completed questionnaires designed to measure expectations for therapeutic benefit, dispositional optimism, unrealistic optimism, and the therapeutic misconception. Results Dispositional optimism was significantly associated with higher expectations for personal therapeutic benefit (Spearman r=0.333, poptimism was weakly associated with unrealistic optimism (Spearman r=0.215, p=0.005). In multivariate analysis, both dispositional optimism (p=0.02) and unrealistic optimism (poptimism (p=.0001), but not dispositional optimism, was independently associated with the therapeutic misconception. Conclusion High expectations for therapeutic benefit among patient-subjects in early phase oncology trials should not be assumed to result from misunderstanding of specific information about the trials. Our data reveal that these expectations are associated with either a dispositionally positive outlook on life or biased expectations about specific aspects of trial participation. Not all manifestations of optimism are the same, and different types of optimism likely have different consequences for informed consent in early phase oncology research. PMID:26882017

  11. The Dual Effects of Critical Thinking Disposition on Worry

    Science.gov (United States)

    Sugiura, Yoshinori

    2013-01-01

    This study investigated the relationship between disposition (people’s consistent motivation) toward critical thinking (CT) and worrying. In spite of its connection to psychopathology, worry is thought to represent an effort at problem-solving. Moreover, worry has been found to be underpinned by cognitive development, leading us to predict a positive relationship between worry and CT disposition. On the other hand, cognitive behavioral therapy, which involves techniques similar to CT, has been shown to be effective in reducing worrying, suggesting that increasing CT disposition decreases worrying. This study attempted to reconcile these seemingly contrasting predictions about the relationship between CT disposition and worrying by using multiple mediator analysis. A model was proposed wherein the mediators, responsibility to continue thinking and detached awareness of negative thinking, were related to two opposing predictions. The former is thought to lead to enhanced worrying and the latter to reduced worrying, with both positively related to CT disposition. A questionnaire study with university students (N = 760) revealed that CT disposition enhanced worrying by obliging people to continue thinking about a problem, but that it also reduced worrying by enhancing the detached and objective awareness of their negative thoughts. This study thus demonstrated the dual effects of CT disposition on worrying through different mediators. Thus, when enhancing CT disposition, it is important for educators to be aware of possible disadvantages apart from its worry-reducing effect. Future studies should therefore examine the underlying mechanisms of these two effects of CT disposition. PMID:24278160

  12. The dual effects of critical thinking disposition on worry.

    Science.gov (United States)

    Sugiura, Yoshinori

    2013-01-01

    This study investigated the relationship between disposition (people's consistent motivation) toward critical thinking (CT) and worrying. In spite of its connection to psychopathology, worry is thought to represent an effort at problem-solving. Moreover, worry has been found to be underpinned by cognitive development, leading us to predict a positive relationship between worry and CT disposition. On the other hand, cognitive behavioral therapy, which involves techniques similar to CT, has been shown to be effective in reducing worrying, suggesting that increasing CT disposition decreases worrying. This study attempted to reconcile these seemingly contrasting predictions about the relationship between CT disposition and worrying by using multiple mediator analysis. A model was proposed wherein the mediators, responsibility to continue thinking and detached awareness of negative thinking, were related to two opposing predictions. The former is thought to lead to enhanced worrying and the latter to reduced worrying, with both positively related to CT disposition. A questionnaire study with university students (N = 760) revealed that CT disposition enhanced worrying by obliging people to continue thinking about a problem, but that it also reduced worrying by enhancing the detached and objective awareness of their negative thoughts. This study thus demonstrated the dual effects of CT disposition on worrying through different mediators. Thus, when enhancing CT disposition, it is important for educators to be aware of possible disadvantages apart from its worry-reducing effect. Future studies should therefore examine the underlying mechanisms of these two effects of CT disposition.

  13. The dual effects of critical thinking disposition on worry.

    Directory of Open Access Journals (Sweden)

    Yoshinori Sugiura

    Full Text Available This study investigated the relationship between disposition (people's consistent motivation toward critical thinking (CT and worrying. In spite of its connection to psychopathology, worry is thought to represent an effort at problem-solving. Moreover, worry has been found to be underpinned by cognitive development, leading us to predict a positive relationship between worry and CT disposition. On the other hand, cognitive behavioral therapy, which involves techniques similar to CT, has been shown to be effective in reducing worrying, suggesting that increasing CT disposition decreases worrying. This study attempted to reconcile these seemingly contrasting predictions about the relationship between CT disposition and worrying by using multiple mediator analysis. A model was proposed wherein the mediators, responsibility to continue thinking and detached awareness of negative thinking, were related to two opposing predictions. The former is thought to lead to enhanced worrying and the latter to reduced worrying, with both positively related to CT disposition. A questionnaire study with university students (N = 760 revealed that CT disposition enhanced worrying by obliging people to continue thinking about a problem, but that it also reduced worrying by enhancing the detached and objective awareness of their negative thoughts. This study thus demonstrated the dual effects of CT disposition on worrying through different mediators. Thus, when enhancing CT disposition, it is important for educators to be aware of possible disadvantages apart from its worry-reducing effect. Future studies should therefore examine the underlying mechanisms of these two effects of CT disposition.

  14. Used fuel disposition in crystalline rocks

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hadgu, Teklu [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kalinina, Elena Arkadievna [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jerden, James L. [Argonne National Lab. (ANL), Argonne, IL (United States); Copple, Jacqueline M. [Argonne National Lab. (ANL), Argonne, IL (United States); Cruse, T. [Argonne National Lab. (ANL), Argonne, IL (United States); Ebert, W. [Argonne National Lab. (ANL), Argonne, IL (United States); Buck, E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Eittman, R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tinnacher, R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Tournassat, Christophe. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Davis, J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Viswanathan, H. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chu, S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dittrich, T. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hyman, F. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Karra, S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Makedonska, N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reimus, P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavarin, Mavrik [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Joseph, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-09-01

    The U.S. Department of Energy Office of Nuclear Energy, Office of Fuel Cycle Technology established the Used Fuel Disposition Campaign (UFDC) in fiscal year 2010 (FY10) to conduct the research and development (R&D) activities related to storage, transportation and disposal of used nuclear fuel and high level nuclear waste. The objective of the Crystalline Disposal R&D Work Package is to advance our understanding of long-term disposal of used fuel in crystalline rocks and to develop necessary experimental and computational capabilities to evaluate various disposal concepts in such media.

  15. Kinetics and

    Directory of Open Access Journals (Sweden)

    Mojtaba Ahmadi

    2016-11-01

    Full Text Available The aqueous degradation of Reactive Yellow 84 (RY84 by potassium peroxydisulfate (K2S2O8 has been studied in laboratory scale experiments. The effect of the initial concentrations of potassium peroxydisulfate and RY84, pH and temperature on RY84 degradation were also examined. Experimental data were analyzed using first and second-order kinetics. The degradation kinetics of RY84 of the potassium peroxydisulfate process followed the second-order reaction kinetics. These rate constants have an extreme values similar to of 9.493 mM−1min−1 at a peroxydisulfate dose of 4 mmol/L. Thermodynamic parameters such as activation (Ea and Gibbs free energy (ΔG° were also evaluated. The negative value of ΔGo and Ea shows the spontaneous reaction natural conditions and exothermic nature.

  16. Impact of Social Studies Curriculum on Empathy Dispositions of ...

    African Journals Online (AJOL)

    This study investigated the impact of social studies curriculum on the affective dispositions of students of Colleges of Education in North-West Zone of Nigeria. The purpose of the study was to determine the level of NCE I and NCE III students' affective dispositions in the area of empathy. One research question and one ...

  17. 50 CFR 216.73 - Disposition of fur seal parts.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Disposition of fur seal parts. 216.73... MAMMALS Pribilof Islands, Taking for Subsistence Purposes § 216.73 Disposition of fur seal parts. Except... part of a fur seal taken for subsistence uses may be sold or otherwise transferred to any person unless...

  18. 50 CFR 30.12 - Disposition of feral animals.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Disposition of feral animals. 30.12... (CONTINUED) THE NATIONAL WILDLIFE REFUGE SYSTEM RANGE AND FERAL ANIMAL MANAGEMENT Feral Animals § 30.12 Disposition of feral animals. Feral animals taken on wildlife refuge areas may be disposed of by sale on the...

  19. Inferring Social Disposition by Sound and Surface Appearance in Infancy

    Science.gov (United States)

    Lyons, Ashley B.; Cheries, Erik W.

    2017-01-01

    Adults automatically infer a person's social disposition and future behavior based on the many properties they observe about how they look and sound. The goal of the current study is to explore the developmental origins of this bias. We tested whether 12-month-old infants automatically infer a character's social disposition (e.g., whether they are…

  20. A Comparison of Preferred Urban Administrative Dispositions between Constituency Groups

    Science.gov (United States)

    Pregot, Michael

    2015-01-01

    This research study analyzes preferred leadership dispositions for teachers, parents, and school leaders. Respondents selected their most preferred dispositions from a list of 20 (Interstate School Leaders Licensure Consortium) leadership standards. Similarities and differences were discerned among the constituent groups. School leaders, teachers,…

  1. 19 CFR 133.52 - Disposition of forfeited merchandise.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Disposition of forfeited merchandise. 133.52... Assessment of Liquidated Damages § 133.52 Disposition of forfeited merchandise. (a) Trademark (other than counterfeit) or trade name violations. Articles forfeited for violation of the trademark laws, other than...

  2. Facilitating Critical and Creative Thinking Dispositions in Children.

    Science.gov (United States)

    Swartz-Tetrault, Alma M.

    The critical and creative thinking dispositions which are intrinsic to children's critical thought may reflect the standards of an adult culture which values verbalized thought over other kinds of human intelligence. Primary critical and creative thinking dispositions are those which help the child explore the world. These are biological processes…

  3. Attending to Ethical and Moral Dispositions in Teacher Education

    Science.gov (United States)

    Osguthorpe, Richard D.

    2013-01-01

    The purpose of this article is to identify some issues related to ethical and moral dispositions in teacher education programs. My intent is to provide a starting point for gaining a professional consensus on the ways that teacher educators approach the definition, assessment, and development of dispositions in their teacher education programs. To…

  4. 42 CFR 35.47 - Disposition of Government checks.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Disposition of Government checks. 35.47 Section 35... Disposition of Government checks. Notwithstanding any other provisions of this subpart, immediately upon... to the department, agency, or establishment of the Government of the United States issuing such...

  5. Critical Thinking Dispositions of Pre-Service Teachers

    Science.gov (United States)

    Bakir, Selda

    2015-01-01

    This study investigated the critical thinking dispositions of pre-service teachers in terms of various variables. The study included 1106 participants and used the survey model and the Turkish version (CCTDI-T) of the California Critical Thinking Disposition Inventory (CCTDI). The reliability of the scale for this study was found to be 0.82. The…

  6. 19 CFR 141.16 - Disposition of documents.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Disposition of documents. 141.16 Section 141.16... Disposition of documents. (a) Bill of lading or air waybill. When the return of the bill of lading or air... been made for the merchandise. (b) Other documents. When any of the other documents specified in § 141...

  7. Gendered Personality Disposition and Gender Role Attitudes among Israeli Students.

    Science.gov (United States)

    Kulik, Liat

    1999-01-01

    Examines the relationship between gendered personality dispositions and two aspects of gender role attitudes (occupational sex typing and gender role stereotypes). Indicates that gendered personality disposition affects occupational sex typing, whereas gender has the strongest effect on stereotypes of gender roles in the family and society.…

  8. The Development and Validation of the Diversity Dispositions Index

    Science.gov (United States)

    Schulte, Laura; Edwards, Sarah; Edick, Nancy

    2008-01-01

    The "No Child Left Behind Act" signed into law in 2002 requires school districts to hire highly qualified teachers who possess the necessary dispositions to ensure that all children learn (Center on Education Policy, 2002). The National Council for Accreditation of Teacher Education (NCATE) (2002) defines dispositions as "the values, commitments,…

  9. Building a Conceptual Framework for Online Educator Dispositions

    Science.gov (United States)

    Kirwan, Jeral R.; Roumell, Elizabeth Anne

    2015-01-01

    It has been argued that online instruction is distinctive from the conventional classroom. If an effective online practice is to emerge, the roles, characteristics and dispositions of the educators themselves should be studied more closely. The aim of this paper was to present an online educator dispositions model that addresses the underlying…

  10. Investigating Academic Achievements and Critical Thinking Dispositions of Teacher Candidates

    Science.gov (United States)

    Karagöl, Ibrahim; Bekmezci, Sinan

    2015-01-01

    The aim of this study is to examine the relationship between academic achievements and critical thinking dispositions of teacher candidates in Faculty of Education and to find out whether critical thinking dispositions and academic achievements scores of teacher candidates differ according to different variables. The population consists of the…

  11. 41 CFR 101-27.406 - Disposition of stock.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Disposition of stock. 101...-Elimination of Items From Inventory § 101-27.406 Disposition of stock. Stocks of slow-moving items which are... this section, shall be taken, as necessary, to remove stocks of inactive items from inventory. (a...

  12. 48 CFR 945.570-7 - Disposition of motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disposition of motor... Disposition of motor vehicles. (a) The contractor shall dispose of DOE-owned motor vehicles as directed by the contracting officer. (b) DOE-owned motor vehicles may be disposed of as exchange/sale items when directed by...

  13. Prediction of critical thinking disposition based on mentoring among ...

    African Journals Online (AJOL)

    The results of study showed that there was a significantly positive correlation between Mentoring and Critical thinking disposition among faculty members. The findings showed that 67% of variance of critical thinking disposition was defined by predictive variables. The faculty members evaluated themselves in all mentoring ...

  14. Applying Gadamer's Concept of Disposition to Science and Science Education

    Science.gov (United States)

    Borda, Emily J.

    2007-01-01

    In this paper, I recall previous arguments for a hermeneutic approach to science and claim that such an approach necessitates attention to the development of dispositions. I undertake an analysis of Hans-Georg Gadamer's philosophical hermeneutics to identify and describe dispositions relevant to a hermeneutic approach to science. I then apply…

  15. Faculty Dispositions: Seeking Clarity while Looking at Muddy Waters

    Science.gov (United States)

    Lund, Jacalyn; Boyce, B. Ann; Oates, Richard; Fiorentino, Leah

    2010-01-01

    If one reads the paper or listens to the news, professional disposition are almost becoming critical job skills in the world of work. Similarly, faculty dispositions, defined in this article as "attitudes, values, and beliefs demonstrated through both verbal and non-verbal behaviors as educators interact with students, families, colleagues, and…

  16. Relationships among Bilingualism, Critical Thinking Ability, and Critical Thinking Disposition.

    Science.gov (United States)

    Albert, Raymond T.; Albert, Rachel E.; Radsma, Jenny

    2002-01-01

    Nursing students (n=111) completed French and English Cloze Tests, the California Critical Thinking Disposition Inventory, and the California Critical Thinking Skills Test. There was insufficient evidence to support a relationship between bilingualism and critical thinking ability or between critical thinking disposition and ability. Bilingualism…

  17. Design and development of a cross-cultural disposition inventory

    Science.gov (United States)

    Davies, Randall; Zaugg, Holt; Tateishi, Isaku

    2015-01-01

    Advances in technology have increased the likelihood that engineers will have to work in a global, culturally diverse setting. Many schools of engineering are currently revising their curricula to help students to develop cultural competence. However, our ability to measure cultural dispositions can be a challenge. The purpose of this project was to develop and test an instrument that measures the various aspects of cultural disposition. The results of the validation process verified that the hypothesised model adequately represented the data. The refined instrument produced a four-factor model for the overall construct. The validation process for the instrument verified the existence of specific subcomponents that form the overall cultural disposition construct. There also seems to be a hierarchical relationship within the subcomponents of cultural disposition. Additional research is needed to explore which aspects of cultural disposition affect an individual's ability to work effectively in a culturally diverse engineering team.

  18. Contribution of Emotional Intelligence towards Graduate Students’ Critical Thinking Disposition

    Directory of Open Access Journals (Sweden)

    Fong-Luan Kang

    2015-10-01

    Full Text Available Good critical thinkers possess a core set of cognitive thinking skills, and a disposition towards critical thinking. They are able to think critically to solve complex, real-world problems effectively. Although personal emotion is important in critical thinking, it is often a neglected issue. The emotional intelligence in this study concerns our sensitivity to and artful handling of our own and others’ emotions. Engaging students emotionally is the key to strengthening their dispositions toward critical thinking. Hence, a study involving 338 male and female graduate students from a public university was carried out. They rated the Emotional Intelligence Scale and Critical Thinking Disposition Scale. Findings suggested that emotional intelligence and critical thinking disposition were positively correlated (r=.609. Differences in terms of age, gender, and course of study also formed part of the analysis. Keywords: emotional intelligence, critical thinking disposition, graduate students

  19. Weapons material disposition: Section II - disposition`s dilemma; Section III - the MOX option: For love or for money?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    In the interests of global security, almost all the nuclear states are now working closely with each other to tackle safeguards and disposition issues that until recently have been caught in the thicklets of international rivalry. An excellent example in the Nuclear Safety and Security Summit held in Moscow in April, attended by government leaders from Canada, France, Germany, Italy, the U.K., the U.S. and the Russian Federation. The Summit Decleration addresses excess weapons materials in term, even outlining specific disposal alternatives, and called for a convention of technical experts to meet in France before year-end to formulate concrete recommendations. As the Summit Decleration also makes clear, however, primary responsibility for solutions lies with the nuclear weapons states themselves, not with other countries or international organizations, specifically the united States and Russia, that we now turn.

  20. An Ungrateful Disposition: Psychometric Properties of the Dispositional Envy Scale in Brazil

    Directory of Open Access Journals (Sweden)

    Emerson Diógenes de Medeiros

    Full Text Available Abstract Envy appears to be found among all cultures, and most individuals seem capable of experiencing it. The aim of this research was to gather evidence of the validity and reliability of the Brazilian version of the Dispositional Envy Scale. For that, we performed two studies, each with 246 university students. In the first study, the results indicated that the instrument is composed of a single component. The second study confirms this structure based on the good fit indices and presents adjustment indicators that comply or approach the recommended criteria in the literature. Both studies demonstrate that the single component instrument presents a good level of reliability, as indicated by levels of internal consistency and homogeneity that exceed those recommended for such studies. Accordingly, it was concluded that the Brazilian-Portuguese version of the Dispositional Envy Scale presents acceptable psychometric characteristics and that it may, therefore, be used to assess the tendency or predisposition to feel envy.

  1. Weapons-grade plutonium dispositioning. Volume 2: Comparison of plutonium disposition options

    Energy Technology Data Exchange (ETDEWEB)

    Brownson, D.A.; Hanson, D.J.; Blackman, H.S. [and others

    1993-06-01

    The Secretary of Energy requested the National Academy of Sciences (NAS) Committee on International Security and Arms Control to evaluate disposition options for weapons-grade plutonium. The Idaho National Engineering Laboratory (INEL) offered to assist the NAS in this evaluation by investigating the technical aspects of the disposition options and their capability for achieving plutonium annihilation levels greater than 90%. This report was prepared for the NAS to document the gathered information and results from the requested option evaluations. Evaluations were performed for 12 plutonium disposition options involving five reactor and one accelerator-based systems. Each option was evaluated in four technical areas: (1) fuel status, (2) reactor or accelerator-based system status, (3) waste-processing status, and (4) waste disposal status. Based on these evaluations, each concept was rated on its operational capability and time to deployment. A third rating category of option costs could not be performed because of the unavailability of adequate information from the concept sponsors. The four options achieving the highest rating, in alphabetical order, are the Advanced Light Water Reactor with plutonium-based ternary fuel, the Advanced Liquid Metal Reactor with plutonium-based fuel, the Advanced Liquid Metal Reactor with uranium-plutonium-based fuel, and the Modular High Temperature Gas-Cooled Reactor with plutonium-based fuel. Of these four options, the Advanced Light Water Reactor and the Modular High Temperature Gas-Cooled Reactor do not propose reprocessing of their irradiated fuel. Time constraints and lack of detailed information did not allow for any further ratings among these four options. The INEL recommends these four options be investigated further to determine the optimum reactor design for plutonium disposition.

  2. The association between resting functional connectivity and dispositional optimism.

    Directory of Open Access Journals (Sweden)

    Qian Ran

    Full Text Available Dispositional optimism is an individual characteristic that plays an important role in human experience. Optimists are people who tend to hold positive expectations for their future. Previous studies have focused on the neural basis of optimism, such as task response neural activity and brain structure volume. However, the functional connectivity between brain regions of the dispositional optimists are poorly understood. Previous study suggested that the ventromedial prefrontal cortex (vmPFC are associated with individual differences in dispositional optimism, but it is unclear whether there are other brain regions that combine with the vmPFC to contribute to dispositional optimism. Thus, the present study used the resting-state functional connectivity (RSFC approach and set the vmPFC as the seed region to examine if differences in functional brain connectivity between the vmPFC and other brain regions would be associated with individual differences in dispositional optimism. The results found that dispositional optimism was significantly positively correlated with the strength of the RSFC between vmPFC and middle temporal gyrus (mTG and negativly correlated with RSFC between vmPFC and inferior frontal gyrus (IFG. These findings may be suggested that mTG and IFG which associated with emotion processes and emotion regulation also play an important role in the dispositional optimism.

  3. The Relationship between Critical Thinking Disposition and Self-Esteem

    Directory of Open Access Journals (Sweden)

    Shirin Iranfar

    2013-12-01

    Full Text Available Introduction: Critical Thinking Disposition indicates individual’s inclination to Critical Thinking, which is one of the domains of personality. Individual characteristics are important and influential factors in the growth and development of students’ Critical Thinking. One of these influential characteristics might be self-esteem, thus this study was to determine the correlation between Critical Thinking Disposition and self-esteem in medical students. Methods: In an analytical cross-sectional study, 289 medical students were selected through stratified random sampling method in Kermanshah University of Medical Sciences in 2011. The instrument for data collection was a questionnaire containing 3 parts: demographic data, California Critical Thinking Disposition Inventory, and Cooper-Smith Self-Esteem Inventory. The results were analyzed by SPSS-16 using descriptive statistics, Pearson and Spearman Correlation Coefficient, ANOVA, Chi-Square and Fisher exact test. Results: Results showed that 98.6% (285 of students had deficiency, 1.4% (4 ambivalence and nobody had positive critical thinking disposition. There was a significantly negative correlation between Critical Thinking Disposition and self-esteem (r=-0.462, P<0.001. Also, there was no a significant relationship between two groups of low self-esteem , high self-esteem , negative and ambivalent Critical Thinking Disposition. Conclusion: It seems that Critical Thinking Disposition, like other psychological variables, is influenced by social factors and social environment plays a role in promoting or undermining it. So, similar studies are recommended to investigate the factors affecting Critical Thinking in medical students.

  4. SOCIAL NETWORKS AS DISPOSITIVES OF NEOLIBERAL GOVERNMENTALITY

    Directory of Open Access Journals (Sweden)

    Julio Cesar Lemes de Castro

    2016-10-01

    Full Text Available This article of theoretical reflection investigates the social networks that emerge in the context of Web 2.0, such as Facebook, as dispositives of neoliberal governmentality in the sense proposed by Foucault. From the standpoint of government of self, the design of social networks establishes a competition for attention that tends to favor the neoliberal culture of performance. In terms of social organization, the way in which users intertwine their connections is paralleled by the neoliberal paradigm of spontaneous market order. Furthermore, the use of personal information on these users, encompassing all their activities within the networks, in order to set up databases to attract advertisers reflects the neoliberal tendency of colonization of the different realms of existence by economic forces. However, the tensions that accompany neoliberal governmentality in social networks reveal its limitations, opening the possibility for these networks to also act as instruments of resistance to neoliberalism.

  5. Kinetic Biochemistry

    OpenAIRE

    Jäntschi, Lorentz

    2003-01-01

    Mathematics and computer programming have a major contribution to chemistry. Two directions can be identified: one that searches and tries (rich) to explain the structural binding and shape of the chemical compounds [1] with major applications in QSPR/QSAR studies [2], and applied sciences such as engineering of materials or agriculture [3]; the second direction is to models the kinetic processes that are involved in chemical reactions [4]. Many such models are available here. The present pap...

  6. Kinetic Biochemistry

    Directory of Open Access Journals (Sweden)

    Lorentz JÄNTSCHI

    2003-03-01

    Full Text Available Mathematics and computer programming have a major contribution to chemistry. Two directions can be identified: one that searches and tries (rich to explain the structural binding and shape of the chemical compounds [1] with major applications in QSPR/QSAR studies [2], and applied sciences such as engineering of materials or agriculture [3]; the second direction is to models the kinetic processes that are involved in chemical reactions [4]. Many such models are available here. The present paper describes three variants of well the known kinetic models and presents the mathematical equations associated with them. The differential equations are numerically solved and fitted with MathCad program. [1] Diudea M., Gutman I., Jäntschi L., Molecular Topology, Nova Science, Huntington, New York, 332 p., 2001, 2002. [2] Diudea M. V., Ed., QSPR / QSAR Studies by Molecular Descriptors, Nova Science, Huntington, New York, 438 p., 2001. [3] Jäntschi L., Microbiology and Toxicology. Phytochemistry Studies (in Romanian, Amici, Cluj-Napoca, 184 p., 2003. [4] Jäntschi L., Unguresan M., Physical Chemistry. Molecular Kinetic and Dynamic (in Romanian, Mediamira, Cluj-Napoca, 159 p., 2001.

  7. Physisorption kinetics

    CERN Document Server

    Kreuzer, Hans Jürgen

    1986-01-01

    This monograph deals with the kinetics of adsorption and desorption of molecules physisorbed on solid surfaces. Although frequent and detailed reference is made to experiment, it is mainly concerned with the theory of the subject. In this, we have attempted to present a unified picture based on the master equation approach. Physisorption kinetics is by no means a closed and mature subject; rather, in writing this monograph we intended to survey a field very much in flux, to assess its achievements so far, and to give a reasonable basis from which further developments can take off. For this reason we have included many papers in the bibliography that are not referred to in the text but are of relevance to physisorption. To keep this monograph to a reasonable size, and also to allow for some unity in the presentation of the material, we had to omit a number of topics related to physisorption kinetics. We have not covered to any extent the equilibrium properties of physisorbed layers such as structures, phase tr...

  8. Preliminary Report on Monosodium Titanate Adsorption Kinetics

    Energy Technology Data Exchange (ETDEWEB)

    Hobbs, D.T.

    1998-12-11

    The Salt Disposition Systems Engineering Team identified the adsorption kinetics of actinides and strontium onto monosodium titanate (MST) as a technical risk for several of the processing alternatives selected for additional evaluation in Phase III of their effort. The Flow Sheet Team requested that the Savannah River Technology Center (SRTC) examine the adsorption kinetics of MST for several process alternatives.This study consisted of a statistically designed set of tests to determine the rate of adsorption of strontium, uranium, neptunium and plutonium as a function of temperature, MST concentration, and concentrations of sodium, strontium, uranium, neptunium and plutonium. Additional tests incorporated into the design assess the effects of mixing as well as the influence from the presence of sludge solids and sodium tetraphenylborate.

  9. Gendered personality disposition and gender role attitudes among Israeli students.

    Science.gov (United States)

    Kulik, L

    1999-12-01

    In a sample of 204 Israeli university students, the author examined the relationship between gendered personality dispositions and 2 aspects of gender role attitudes: occupational sex typing and gender role stereotypes. Evaluations of occupational gender attributes were the least sex typed among participants in the androgynous group. At the same time, contrary to expectations, the participants in the undifferentiated and sex-typed groups had relatively stereotyped perceptions of occupations. However, no relationship was found between gendered personality disposition and stereotyped perceptions of gender roles. Regardless of gendered personality disposition, the women, compared with the men, had more liberal attitudes toward gender roles.

  10. Americium/Curium Disposition Life Cycle Planning Study

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, W.N. [Westinghouse Savannah River Company, AIKEN, SC (United States); Krupa, J.; Stutts, P.; Nester, S.; Raimesch, R.

    1998-04-30

    At the request of the Department of Energy Savannah River Office (DOE- SR), Westinghouse Savannah River Company (WSRC) evaluated concepts to complete disposition of Americium and Curium (Am/Cm) bearing materials currently located at the Savannah River Site (SRS).

  11. SELECTION OF SURPLUS PLUTONIUM MATERIALS FOR DISPOSITION TO WIPP

    Energy Technology Data Exchange (ETDEWEB)

    Allender, J.; Mcclard, J.; Christopher, J.

    2012-06-08

    The U.S. Department of Energy (DOE) is preparing a Surplus Plutonium Disposition (SPD) Supplemental Environmental Impact Statement (SEIS). Included in the evaluation are up to 6 metric tons (MT) of plutonium in the form of impure oxides and metals for which a disposition plan has not been decided, among options that include preparation as feed for the Mixed Oxide Fuel Fabrication Facility; disposing to high-level waste through the Savannah River Site (SRS) HB Line and H Canyon; can-in-canister disposal using the SRS Defense Waste Processing Facility; and preparation for disposal at the Waste Isolation Pilot Plant (WIPP). DOE and SRS have identified at least 0.5 MT of plutonium that, because of high levels of chemical and isotopic impurities, is impractical for disposition by methods other than the WIPP pathway. Characteristics of these items and the disposition strategy are discussed.

  12. 27 CFR 28.107 - Disposition of forms.

    Science.gov (United States)

    2010-04-01

    ... to a Manufacturing Bonded Warehouse § 28.107 Disposition of forms. TTB Form 5100.11 and any... TTB Form 5100.11. (Approved by the Office of Management and Budget under control number 1512-0250...

  13. Hearing Office Dispositions Per ALJ Per Day Rate Ranking Report

    Data.gov (United States)

    Social Security Administration — A ranking of ODAR hearing offices by the average number of hearings dispositions per ALJ per day. The average shown will be a combined average for all ALJs working...

  14. The Relationship between Critical Thinking Disposition and Self-Esteem

    OpenAIRE

    Shirin Iranfar; Vida Sepahi; Ahmad Khoshay; Farahnaz Keshavarzi

    2013-01-01

    Introduction: Critical Thinking Disposition indicates individual’s inclination to Critical Thinking, which is one of the domains of personality. Individual characteristics are important and influential factors in the growth and development of students’ Critical Thinking. One of these influential characteristics might be self-esteem, thus this study was to determine the correlation between Critical Thinking Disposition and self-esteem in medical students. Methods: In an analytical cross-sec...

  15. URGENSI STRATEGI DISPOSITION HABITS OF MIND MATEMATIS

    Directory of Open Access Journals (Sweden)

    Bety Miliyawati

    2014-09-01

    Full Text Available ABSTRAK Kebiasaan berpikir (habits of mind memiliki peranan penting dalam proses pembelajaran dan perkembangan individu dalam membantu memecahkan masalah. Habits Of Mind (HOM adalah kebiasaan berpikir secara fleksibel, mengelola secara empulsif, mendengarkan dengan empati, membiasakan mengajukan pertanyaan, kebiasaan menyelesaikan masalah secara efektif, membiasakan menggunakan pengetahuan masa lalu untuk situasi baru, membiasakan berkomunikasi, berpikir jernih dengan tepat, menggunakan semua indera ketika mengumpulkan informasi, mencoba cara berbeda dan menghasilkan ide-ide yang baru, kebiasaan untuk merespon, kebiasaan untuk mengambil resiko, biasa bertanggung jawab, memiliki rasa humor, membiasakan berpikir interaktif dengan orang lain, bersikap terbuka dan mencoba terus-menerus. Hal ini sejalan dengan tujuan Kurikulum 2013, yaitu mempersiapkan generasi bangsa agar memiliki kemampuan hidup sebagai pribadi dan warga negara yang produktif, kreatif, inovatif, dan afektif. Artikel ini dikaji didasarkan atas analisis terhadap: (1 karakteristik matematika, (2 habits of mind matematis, dan (3 disposition contoh strategi HOM dalam pembelajaran matematika yang dikembangkan pada siswa. Kata Kunci    : Pembelajaran, Karakteristik Matematika, Habits of Mind Matematis   ABSTRACT Habits of mind have an important role in the learning process and the development of individuals in helping to solve the problem. Habits Of Mind (HOM is the habit of thinking flexibly, manage empulsif, listening with empathy, get used to ask questions, solve problems effectively habit, the habit of using past knowledge to new situations, to get used to communicate, think clearly, precisely, using all the senses when gathering information, trying different ways and generate new ideas, habits to respond, the habit to take risks, the usual charge, have a sense of humor, familiarize interactive thinking with others, be open and try constantly. This is in line with the curriculum

  16. Salt disposition alternatives filtration at SRTC

    Energy Technology Data Exchange (ETDEWEB)

    Walker, B. W.; Hobbs, D.

    2000-01-27

    Several of the prospective salt disposition alternative technologies require a monosodium titanate (MST) contact to remove strontium and actinides from inorganic salt solution feedstock. This feedstock also contains sludge solids from waste removal operations and may contain defoamers added in the evaporator systems. Filtration is required to remove the sludge and MST solids before sending the salt solution for further processing. This report describes testing performed using the Parallel Theological Experimental Filter (PREF). The PREF contains two single tube Mott sintered metal crossflow filters. For this test one filter was isolated so that the maximum velocities could be achieved. Previous studies showed slurries of MST and sludge in the presence of sodium tetraphenylborate (NaTPB) were filterable since the NaTPB slurry formed a filter cake which aided in removing the smaller MST and sludge particles. Some of the salt disposition alternative technologies do not use NaTPB raising the question of how effective crossflow filtration is with a feed stream containing only sludge and MST. Variables investigated included axial velocity, transmembrane pressure, defoamer effects, and solids concentration (MST and sludge). Details of the tests are outlined in the technical report WSRC-RP-98-O0691. Key conclusions from this study are: (1) Severe fouling of the Mott sintered metal filter did not occur with any of the solutions filtered. (2) The highest fluxes, in the range of .46 to 1.02 gpm/f{sup 2}, were obtained when salt solution decanted from settled solids was fed to the filter. These fluxes would achieve 92 to 204 gpm filtrate production for the current ITP filters. The filtrate fluxes were close to the flux of 0.42 gpm/f{sup 2} reported for In Tank Precipitation Salt Solution by Morrisey. (3) For the range of solids loading studied, the filter flux ranged from .04 to .17 gpm/f{sup 2} which would result in a filtrate production rate of 9 to 31 gpm for the current HP

  17. Accessing and assessing young learner’s mathematical dispositions

    Directory of Open Access Journals (Sweden)

    mellony Graven

    2012-07-01

    Full Text Available It is argued in this paper that there is an absence of literature relating to research on learner mathematical dispositions, particularly with young learners. Drawing on Kilpatrick, Swafford and Findell’s (2001 five interrelated strands of mathematical proficiency, which include: conceptual understanding, procedural fluency, strategic competence, adaptive reasoning and productive disposition, it is argued that there has been little engagement with productive disposition in the field of mathematics education and how we might access and assess this strand. Despite competence in all strands being essential for mathematical proficiency, literature and assessments that seek to establish learner levels of mathematical proficiency have tended to focus on the first four and have neglected the last; productive disposition. Finding ways in which to access student mathematical learning dispositions can be challenging, especially with young learners who struggle to articulate their views. An instrument is shared that the author has designed with doctoral fellow, Debbie Stott, in order to access and assess the productive disposition of learners participating in maths clubs run within the South African Numeracy Chair. The findings that emerge in one Grade 3 club with six learners is shared. These findings are related to the data collected through instruments that assess the other four strands of mathematical proficiency. This enables a holistic picture of learner’s mathematical proficiency as intended in the conceptualisation of the interrelated five strands of proficiency.

  18. [Critical thinking disposition and clinical competence in general hospital nurses].

    Science.gov (United States)

    Park, Jin-Ah; Kim, Bog-Ja

    2009-12-01

    This study was done to investigate the relationship between critical thinking disposition and clinical competence among nurses in general hospitals. This study was a descriptive-correlational study with a convenience sample of 560 nurses from 5 general hospitals. The data were collected by self-administered questionnaires. Critical thinking disposition was measured using the Critical Thinking Disposition Scale for Nursing Students. Clinical competence was measured using the Standardized Nurse Performance Appraisal Tool. The mean score for critical thinking disposition and clinical competence was 3.37 and 4.10 respectively on a 5 point scale. A statistically significant correlation was found between critical thinking disposition and clinical competence. A regression model explained 72.8% of clinical competence. Prudence is the most significant predictor of clinical competence (R(2)=.728). Study findings suggest that nurses with a higher level of critical thinking disposition would have a higher level of clinical competence. Furthermore, prudence might be the most important predictor of clinical competence. In order to strengthen clinical competence in nurses, the development and enhancement of critical thinking should be emphasized at the college level and nurses should be encouraged to make a clinical decision with greater prudence.

  19. The disposition of suxibuzone in the horse.

    Science.gov (United States)

    Delbeke, F T; Vynckier, L; Debackere, M

    1993-09-01

    A high performance liquid chromatographic method is described to determine the anti-inflammatory drug suxibuzone (SXB) and its major metabolites phenylbutazone (PBZ) and oxyphenbutazone (OPBZ) in equine plasma and urine. When suxibuzone (6 mg/kg) was administered intravenously (i.v.) or orally (p.o.) no parent drug was detected in plasma or in urine. The disposition of the metabolite PBZ (i.v.) could be described by a 2 compartment model with a beta half-life varying from 7.40 to 8.35 h. Due to severe side effects the use of i.v. suxibuzone should not be encouraged in the horse. PBZ and OPBZ were detected in plasma and urine after p.o. SXB administration. Peak plasma PBZ concentrations (8.8 +/- 3.0 micrograms/ml) occurred 6 h after oral dosing and the terminal exponential constant was 0.11 +/- 0.01 h-1. Phenylbutazone and oxyphenbutazone were detectable in urine (> 1 microgram/ml) for at least 36 h, after p.o. administration. SXB was not hydrolyzed in vitro by horse plasma. Equine liver homogenates however appeared to have a very high capacity for hydrolysing SXB, indicating that first-pass effect could be responsible for the rapid disappearance of this NSAID in the horse.

  20. ISS Logistics Hardware Disposition and Metrics Validation

    Science.gov (United States)

    Rogers, Toneka R.

    2010-01-01

    I was assigned to the Logistics Division of the International Space Station (ISS)/Spacecraft Processing Directorate. The Division consists of eight NASA engineers and specialists that oversee the logistics portion of the Checkout, Assembly, and Payload Processing Services (CAPPS) contract. Boeing, their sub-contractors and the Boeing Prime contract out of Johnson Space Center, provide the Integrated Logistics Support for the ISS activities at Kennedy Space Center. Essentially they ensure that spares are available to support flight hardware processing and the associated ground support equipment (GSE). Boeing maintains a Depot for electrical, mechanical and structural modifications and/or repair capability as required. My assigned task was to learn project management techniques utilized by NASA and its' contractors to provide an efficient and effective logistics support infrastructure to the ISS program. Within the Space Station Processing Facility (SSPF) I was exposed to Logistics support components, such as, the NASA Spacecraft Services Depot (NSSD) capabilities, Mission Processing tools, techniques and Warehouse support issues, required for integrating Space Station elements at the Kennedy Space Center. I also supported the identification of near-term ISS Hardware and Ground Support Equipment (GSE) candidates for excessing/disposition prior to October 2010; and the validation of several Logistics Metrics used by the contractor to measure logistics support effectiveness.

  1. TRACKING SURPLUS PLUTONIUM FROM WEAPONS TO DISPOSITION

    Energy Technology Data Exchange (ETDEWEB)

    Allender, J.; Beams, J.; Sanders, K.; Myers, L.

    2013-07-16

    Supporting nuclear nonproliferation and global security principles, beginning in 1994 the United States has withdrawn more than 50 metric tons (MT) of government-controlled plutonium from potential use in nuclear weapons. The Department of Energy (DOE), including the National Nuclear Security Administration, established protocols for the tracking of this "excess" and "surplus" plutonium, and for reconciling the current storage and utilization of the plutonium to show that its management is consistent with the withdrawal policies. Programs are underway to ensure the safe and secure disposition of the materials that formed a major part of the weapons stockpile during the Cold War, and growing quantities have been disposed as waste, after which they are not included in traditional nuclear material control and accountability (NMC&A) data systems. A combination of resources is used to perform the reconciliations that form the basis for annual reporting to DOE, to U.S. Department of State, and to international partners including the International Atomic Energy Agency.

  2. Kinetic buffers.

    Science.gov (United States)

    Alibrandi, Giuseppe; Fabbrizzi, Luigi; Licchelli, Maurizio; Puglisi, Antonio

    2015-01-12

    This paper proposes a new type of molecular device that is able to act as an inverse proton sponge to slowly decrease the pH inside a reaction vessel. This makes the automatic monitoring of the concentration of pH-sensitive systems possible. The device is a composite formed of an alkyl chloride, which kinetically produces acidity, and a buffer that thermodynamically modulates the variation in pH value. Profiles of pH versus time (pH-t plots) have been generated under various experimental conditions by computer simulation, and the device has been tested by carrying out automatic spectrophotometric titrations, without using an autoburette. To underline the wide variety of possible applications, this new system has been used to realize and monitor HCl uptake by a di-copper(II) bistren complex in a single run, in a completely automatic experiment. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Residence time dispersion as a general measure of drug distribution kinetics: estimation and physiological interpretation.

    Science.gov (United States)

    Weiss, Michael

    2007-11-01

    To evaluate distribution kinetics of drugs by the relative dispersion of disposition residence time and demonstrate its uses, interpretation and limitations. The relative dispersion was estimated from drug disposition data of inulin and digoxin fitted by three-exponential functions, and calculated from compartmental parameters published for fentanyl and alfentanil. An interpretation is given in terms of a lumped organs model and the distributional equilibration process in a noneliminating system. As a measure of the deviation from mono-exponential disposition (one-compartment behavior), the relative dispersion provides information on the distribution kinetics of drugs, i.e., diffusion-limited distribution or slow tissue binding, without assuming a specific structural model. It also defines the total distribution clearance which has a clear physical meaning. The residence time dispersion is a model-independent measure that can be used to characterize the distribution kinetics of drugs and to reveal the influence of disease states. It can be estimated with high precision from drug disposition data.

  4. SLIGHTLY IRRADIATED FUEL (SIF) INTERIM DISPOSITION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    NORTON SH

    2010-02-23

    CH2M HILL Plateau Remediation Company (CH2M HILL PRC) is proud to submit the Slightly Irradiated Fuel (SIF) Interim Disposition Project for consideration by the Project Management Institute as Project of the Year for 2010. The SIF Project was a set of six interrelated sub-projects that delivered unique stand-alone outcomes, which, when integrated, provided a comprehensive and compliant system for storing high risk special nuclear materials. The scope of the six sub-projects included the design, construction, testing, and turnover of the facilities and equipment, which would provide safe, secure, and compliant Special Nuclear Material (SNM) storage capabilities for the SIF material. The project encompassed a broad range of activities, including the following: Five buildings/structures removed, relocated, or built; Two buildings renovated; Structural barriers, fencing, and heavy gates installed; New roadways and parking lots built; Multiple detection and assessment systems installed; New and expanded communication systems developed; Multimedia recording devices added; and A new control room to monitor all materials and systems built. Project challenges were numerous and included the following: An aggressive 17-month schedule to support the high-profile Plutonium Finishing Plant (PFP) decommissioning; Company/contractor changeovers that affected each and every project team member; Project requirements that continually evolved during design and construction due to the performance- and outcome-based nature ofthe security objectives; and Restrictions imposed on all communications due to the sensitive nature of the projects In spite of the significant challenges, the project was delivered on schedule and $2 million under budget, which became a special source of pride that bonded the team. For years, the SIF had been stored at the central Hanford PFP. Because of the weapons-grade piutonium produced and stored there, the PFP had some of the tightest security on the Hanford

  5. Adoption first? The disposition of human embryos.

    Science.gov (United States)

    Murphy, Timothy F

    2014-06-01

    Anja Karnein has suggested that because of the importance of respect for persons, law and policy should require some human embryos created in vitro to be available for adoption for a period of time. If no one comes forward to adopt the embryos during that time, they may be destroyed (in the case of embryos left over from fertility medicine) or used in research (in the case of embryos created for that purpose or left over from fertility medicine). This adoption option would increase the number of embryos available for couples looking for help in having children, but that effect is less important--Karnein argues--than the observance of respect for human persons. As possible persons, she holds that embryos ought to be treated, as if they will become children, if only for a while. If enacted as a matter of law and policy, an 'adoption option' would wrongly interfere with the dispositional rights women and men ought to have over embryos they create in the course of trying to have children. Karnein's proposal would also deprive researchers of certainty that the embryos they create for research would actually be available that way, leading to increased burdens of time and money and maybe even to more embryos than would otherwise be produced. Karnein's analysis does not show, moreover, that any duty of rescue applies to embryos. No woman is required to adopt any embryo, which significantly undercuts the justification for an obligatory adoption period. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. Embryo disposition and the new death scene

    Directory of Open Access Journals (Sweden)

    Ellison, David

    2011-01-01

    Full Text Available In the IVF clinic - a place designed principally for the production and implantation of embryos - scientists and IVF recipients are faced with decisions regarding the disposition of frozen embryos. At this time there are hundred of thousands of cryopreserved embryos awaiting such determinations. They may be thawed for transfer to the woman herself, they may be donated for research or for use by other infertile couples, they may remain in frozen storage, or they may variously be discarded by being allowed to 'succumb', or 'perish'. Where the choice is discard, some IVF clients have chosen to formalise the process through ceremony. A new language is emerging in response to the desires of the would-be-parents who might wish to characterise the discard experience as a ‘good death’. This article examines the procedure known as ‘compassionate transfer’ where the embryo to be discarded is placed in the woman’s vagina where it is clear that it will not develop further. An alternate method has the embryo transferred in the usual manner but without the benefit of fertility-enhancing hormones at a point in the cycle unreceptive to implantation. The embryo destined for disposal is thus removed from the realm of technological possibility and ‘returned’ to the female body for a homely death. While debates continue about whether or not embryos constitute life, new practices are developing in response to the emotional experience of embryo discard. We argue that compassionate transfer is a death scene taking shape. In this article, we take the measure of this new death scene’s fabrication, and consider the form, significance, and legal complexity of its ceremonies.

  7. Tryptophan metabolism, disposition and utilization in pregnancy

    Science.gov (United States)

    Badawy, Abdulla A.-B.

    2015-01-01

    Tryptophan (Trp) requirements in pregnancy are several-fold: (1) the need for increased protein synthesis by mother and for fetal growth and development; (2) serotonin (5-HT) for signalling pathways; (3) kynurenic acid (KA) for neuronal protection; (4) quinolinic acid (QA) for NAD+ synthesis (5) other kynurenines (Ks) for suppressing fetal rejection. These goals could not be achieved if maternal plasma [Trp] is depleted. Although plasma total (free + albumin-bound) Trp is decreased in pregnancy, free Trp is elevated. The above requirements are best expressed in terms of a Trp utilization concept. Briefly, Trp is utilized as follows: (1) In early and mid-pregnancy, emphasis is on increased maternal Trp availability to meet the demand for protein synthesis and fetal development, most probably mediated by maternal liver Trp 2,3-dioxygenase (TDO) inhibition by progesterone and oestrogens. (2) In mid- and late pregnancy, Trp availability is maintained and enhanced by the release of albumin-bound Trp by albumin depletion and non-esterified fatty acid (NEFA) elevation, leading to increased flux of Trp down the K pathway to elevate immunosuppressive Ks. An excessive release of free Trp could undermine pregnancy by abolishing T-cell suppression by Ks. Detailed assessment of parameters of Trp metabolism and disposition and related measures (free and total Trp, albumin, NEFA, K and its metabolites and pro- and anti-inflammatory cytokines in maternal blood and, where appropriate, placental and fetal material) in normal and abnormal pregnancies may establish missing gaps in our knowledge of the Trp status in pregnancy and help identify appropriate intervention strategies. PMID:26381576

  8. Validation of Yoon's Critical Thinking Disposition Instrument.

    Science.gov (United States)

    Shin, Hyunsook; Park, Chang Gi; Kim, Hyojin

    2015-12-01

    The lack of reliable and valid evaluation tools targeting Korean nursing students' critical thinking (CT) abilities has been reported as one of the barriers to instructing and evaluating students in undergraduate programs. Yoon's Critical Thinking Disposition (YCTD) instrument was developed for Korean nursing students, but few studies have assessed its validity. This study aimed to validate the YCTD. Specifically, the YCTD was assessed to identify its cross-sectional and longitudinal measurement invariance. This was a validation study in which a cross-sectional and longitudinal (prenursing and postnursing practicum) survey was used to validate the YCTD using 345 nursing students at three universities in Seoul, Korea. The participants' CT abilities were assessed using the YCTD before and after completing an established pediatric nursing practicum. The validity of the YCTD was estimated and then group invariance test using multigroup confirmatory factor analysis was performed to confirm the measurement compatibility of multigroups. A test of the seven-factor model showed that the YCTD demonstrated good construct validity. Multigroup confirmatory factor analysis findings for the measurement invariance suggested that this model structure demonstrated strong invariance between groups (i.e., configural, factor loading, and intercept combined) but weak invariance within a group (i.e., configural and factor loading combined). In general, traditional methods for assessing instrument validity have been less than thorough. In this study, multigroup confirmatory factor analysis using cross-sectional and longitudinal measurement data allowed validation of the YCTD. This study concluded that the YCTD can be used for evaluating Korean nursing students' CT abilities. Copyright © 2015. Published by Elsevier B.V.

  9. Characterization of the hepatic disposition of lanoteplase, a rationally designed variant of tissue plasminogen activator in rodents.

    Science.gov (United States)

    Komoriya, Kazumi; Kato, Yukio; Hayashi, Yujiro; Ohsuye, Kazuhiro; Nishigaki, Ryuichiro; Sugiyama, Yuichi

    2007-03-01

    Lanoteplase is a recombinant mutant of tissue-type plasminogen activator (t-PA) that was developed with an aim to overcome the drawback of rapid systemic elimination of t-PA. In this study, we examined the disposition profile of lanoteplase in vivo and the kinetics of receptor-mediated endocytosis (RME) of this recombinant t-PA in vitro to kinetically characterize the mechanism(s) underlying its tissue distribution and elimination. Integration plot analysis of the initial-phase tissue distribution in rats revealed a much lower uptake clearance (CL(uptake)) of lanoteplase in the liver than that of t-PA. Rate constants for cell surface binding, internalization, and degradation of lanoteplase were also lower than those for t-PA in primary cultured rat hepatocytes. These results suggest that the improved stability of lanoteplase in vivo could be accounted for by the delay in the RME of this recombinant protein. The CL(uptake) in the liver decreased with coadministration of lactoferrin, a ligand for the low-density lipoprotein receptor-related protein (LRP) and the asialoglycoprotein (ASGP) receptors in normal mice, and in lrpap1((-/-)) mice, which have a hereditary deficiency of LRP; In contrast, CL(uptake) was not affected by mannose, whereas that of t-PA decreased with both ligands and in the lrpap1((-/-)) mice. Thus, the hepatic disposition of lanoteplase seems to be mediated by common specific receptors for t-PA, including LRP and the ASGP receptors, whereas the mannose receptor seems to be only minimally involved in the disposition of lanoteplase.

  10. Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice.

    Science.gov (United States)

    Wang, Xiao-Xing; Li, Yang-Bing; Feng, Meihua R; Smith, David E

    2018-01-05

    To develop a semi-mechanistic population pharmacokinetic (PK) model to quantitate the disposition kinetics of L-histidine, a peptide-histidine transporter 1 (PHT1) substrate, in the plasma, cerebrospinal fluid and brain parenchyma of wildtype (WT) and Pht1 knockout (KO) mice. L-[ 14 C]Hisidine (L-His) was administrated to WT and KO mice via tail vein injection, after which plasma, cerebrospinal fluid (CSF) and brain parenchyma samples were collected. A PK model was developed using non-linear mixed effects modeling (NONMEM). The disposition of L-His between the plasma, brain, and CSF was described by a combination of PHT1-mediated uptake, CSF bulk flow and first-order micro-rate constants. The PK profile of L-His was best described by a four-compartment model. A more rapid uptake of L-His in brain parenchyma was observed in WT mice due to PHT1-mediated uptake, a process characterized by a Michaelis-Menten component (V max  = 0.051 nmoL/min and K m  = 34.94 μM). A semi-mechanistic population PK model was successfully developed, for the first time, to quantitatively characterize the disposition kinetics of L-His in brain under in vivo conditions. This model may prove a useful tool in predicting the uptake of L-His, and possibly other PHT1 peptide/mimetic substrates, for drug delivery to the brain.

  11. PBL and critical thinking disposition in Chinese medical students

    DEFF Research Database (Denmark)

    Du, Xiangyun; Emmersen, Jeppe; Toft, Egon

    2013-01-01

    The purpose of this study was to explore the relationship of problem-based learning (PBL) and the development of critical thinking disposition (CT) and academic achievement in Chinese medical students using a cross-sectional randomized design. Medical students from China Medical University (CMU) ...... of critical thinking, but not to improved academic skills.......The purpose of this study was to explore the relationship of problem-based learning (PBL) and the development of critical thinking disposition (CT) and academic achievement in Chinese medical students using a cross-sectional randomized design. Medical students from China Medical University (CMU......) were randomized to PBL or non-PBL teaching at the commencement of the study. After five years of study, CT was scored by a Chinese version of the California Critical Thinking Disposition Inventory (CCTDI-CV). The score achieved on a Computer Case Simulation (CCS) test evaluated academic performance...

  12. Dispositional anxiety blocks the psychological effects of power.

    Science.gov (United States)

    Maner, Jon K; Gailliot, Matthew T; Menzel, Andrew J; Kunstman, Jonathan W

    2012-11-01

    A growing body of research demonstrates that power promotes a fundamental orientation toward approach and agency. The current studies suggest that this tendency is moderated by dispositional anxiety. In two experiments, high levels of dispositional anxiety blocked the psychological effects of power. Although people low in anxiety responded to a power prime with greater willingness to take risks, those high in anxiety did not (Experiment 1). Similarly, whereas those low in social anxiety responded to power with increased sexual attraction toward a confederate, individuals high in social anxiety failed to show the same effect (Experiment 2). In both studies, the interaction between power and anxiety was statistically mediated by perceptions of reward. Although power enhanced people's perceptions of reward, this effect was eliminated by high levels of dispositional anxiety. This research provides insight into how, and in whom, power promotes approach and agentic behavior.

  13. Pediatric Disposition Classification (Reverse Triage) System to Create Surge Capacity.

    Science.gov (United States)

    Kelen, Gabor D; Sauer, Lauren; Clattenburg, Eben; Lewis-Newby, Mithya; Fackler, James

    2015-06-01

    Critically insufficient pediatric hospital capacity may develop during a disaster or surge event. Research is lacking on the creation of pediatric surge capacity. A system of "reverse triage," with early discharge of hospitalized patients, has been developed for adults and shows great potential but is unexplored in pediatrics. We conducted an evidence-based modified-Delphi consensus process with 25 expert panelists to derive a disposition classification system for pediatric inpatients on the basis of risk tolerance for a consequential medical event (CME). For potential validation, critical interventions (CIs) were derived and ranked by using a Likert scale to indicate CME risk should the CI be withdrawn or withheld for early disposition. Panelists unanimously agreed on a 5-category risk-based disposition classification system. The panelists established upper limit (mean) CME risk for each category as surge events.

  14. Hospital Discharge Disposition of Stroke Patients in Tennessee.

    Science.gov (United States)

    Cho, Jin S; Hu, Zhen; Fell, Nancy; Heath, Gregory W; Qayyum, Rehan; Sartipi, Mina

    2017-09-01

    Early determination of hospital discharge disposition status at an acute admission is extremely important for stroke management and the eventual outcomes of patients with stroke. We investigated the hospital discharge disposition of patients with stroke residing in Tennessee and developed a predictive tool for clinical adoption. Our investigational aims were to evaluate the association of selected patient characteristics with hospital discharge disposition status and predict such status at the time of an acute stroke admission. We analyzed 127,581 records of patients with stroke hospitalized between 2010 and 2014. Logistic regression was used to generate odds ratios with 95% confidence intervals to examine the factor outcome association. An easy-to-use clinical predictive tool was built by using integer-based risk scores derived from coefficients of multivariable logistic regression. Among the 127,581 records of patients with stroke, 86,114 (67.5%) indicated home discharge and 41,467 (32.5%) corresponded to facility discharge. All considered patient characteristics had significant correlations with hospital discharge disposition status. Patients were at greater odds of being discharged to another facility if they were women; older; black; patients with a subarachnoid or intracerebral hemorrhage; those with the comorbidities of diabetes mellitus, heart disease, hypertension, chronic kidney disease, arrhythmia, or depression; those transferred from another hospital; or patients with Medicare as the primary payer. A predictive tool had a discriminatory capability with area under the curve estimates of 0.737 and 0.724 for derivation and validation cohorts, respectively. Our investigation revealed that the hospital discharge disposition pattern of patients with stroke in Tennessee was associated with the key patient characteristics of selected demographics, clinical indicators, and insurance status. These analyses resulted in the development of an easy-to-use predictive

  15. Long-lasting effects of affective disorders and childhood trauma on dispositional optimism

    NARCIS (Netherlands)

    Broekhof, Rosalie; Rius-Ottenheim, Nathaly; Spinhoven, Philip; van der Mast, Roos C.; Penninx, Brenda W. J. H.; Zitman, Frans G.; Giltay, Erik J.

    2015-01-01

    Background: Dispositional optimism, a personality trait characterized by generalized positive expectations towards the future, is thought to remain rather stable over time. It is however largely unknown to what extent affective disorders and its risk factors affect dispositional optimism. Methods:

  16. Rethinking Students’ Dispositions towards Civic Duties in Urban Learning Ecologies

    Directory of Open Access Journals (Sweden)

    Olugbenga Adedayo Ige

    2017-10-01

    Full Text Available This study explored the causative influence of thinking dispositions on secondary school students’ civic attitudes in school ecologies. 167 students from eight selected secondary schools in northern and southern Nigeria responded to the Senior Students’ Thinking Dispositions Questionnaire (SSTDQ, and Students’ Attitude to Civic Education Scale (SACES. Results of the stepwise linear regression model declared that absolutism, superstition, and dogmatism were the potent predictors that are strongly connected to students’ civic attitudes. The study has inferences for teachers’ development viz a viz teaching students’ civic attitudes from inside out (critical teaching that uses social tools as yardstick in school ecologies.

  17. Computational Analysis of the SRS Phase III Salt Disposition Alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Dimenna, R.A.

    1999-10-07

    Completion of the Phase III evaluation and comparison of salt disposition alternatives was supported with enhanced computer models and analysis for each case on the ''short list'' of four options. SPEEDUP(TM) models and special purpose models describing mass and energy balances and flow rates were developed and used to predict performance and production characteristics for each of the options. Results from the computational analysis were a key part of the input used to select a primary and an alternate salt disposition alternative.

  18. Decision model for evaluating reactor disposition of excess plutonium

    Energy Technology Data Exchange (ETDEWEB)

    Edmunds, T.

    1995-02-01

    The US Department of Energy is currently considering a range of technologies for disposition of excess weapon plutonium. Use of plutonium fuel in fission reactors to generate spent fuel is one class of technology options. This report describes the inputs and results of decision analyses conducted to evaluate four evolutionary/advanced and three existing fission reactor designs for plutonium disposition. The evaluation incorporates multiple objectives or decision criteria, and accounts for uncertainty. The purpose of the study is to identify important and discriminating decision criteria, and to identify combinations of value judgments and assumptions that tend to favor one reactor design over another.

  19. An Improved Phase Disposition SPWM Strategy for Cascaded Multilevel Inverter

    Directory of Open Access Journals (Sweden)

    Jinbang Xu

    2014-01-01

    Full Text Available The Carrier Phase Shifted (CPS strategy is conventional for cascaded multilevel inverter, because it can naturally ensure all cascaded cells to output balanced power. However, in point of spectra of the output line voltage, CPS is suboptimal to Phase Disposition (PD strategy, because the latter can not naturally ensure power balance. This paper presents an improved PD strategy, inspiration from the disposition of CPS strategy triangle carriers. Just reconstructing the triangle carriers of PD strategy, it can not only reserve the waveform quality of the line voltage to be optimal, but also naturally ensure the output power of each cascaded cells to be balanced.

  20. Influence of flunixin on the disposition kinetic of cefepime in goats.

    Science.gov (United States)

    El-Hewaity, Mohamed

    2014-01-01

    The pharmacokinetic profile of cefepime (10 mg/kg b.w.) was studied following intravenous and intramuscular administration of cefepime alone and coadministered with flunixin (2.2 mg/kg b.w.) in goats. Cefepime concentrations in serum were determined by microbiological assay technique using Escherichia coli (MTCC 443) as test organism. Following intravenous injection of cefepime alone and in combination with flunixin, there are no significant changes in the pharmacokinetic parameters. Following intramuscular injection of cefepime alone and in combination with flunixin, the maximum serum concentration was significantly increased in flunixin coadministered group compared with cefepime alone. However, no significant changes were reported in other pharmacokinetic parameters. The result of in vitro protein binding study indicated that 15.62% of cefepime was bound to goat's serum protein. The mean bioavailability was 92.66% and 95.27% in cefepime alone and coadministered with flunixin, respectively. The results generated from the present study suggest that cefepime may be coadministered with flunixin without change in dose regimen. Cefepime may be given intramuscularly at 12 h intervals to combat susceptible bacterial infections.

  1. Influence of Flunixin on the Disposition Kinetic of Cefepime in Goats

    OpenAIRE

    El-Hewaity, Mohamed

    2014-01-01

    The pharmacokinetic profile of cefepime (10 mg/kg b.w.) was studied following intravenous and intramuscular administration of cefepime alone and coadministered with flunixin (2.2 mg/kg b.w.) in goats. Cefepime concentrations in serum were determined by microbiological assay technique using Escherichia coli (MTCC 443) as test organism. Following intravenous injection of cefepime alone and in combination with flunixin, there are no significant changes in the pharmacokinetic parameters. Followin...

  2. Influence of Flunixin on the Disposition Kinetic of Cefepime in Goats

    Directory of Open Access Journals (Sweden)

    Mohamed El-Hewaity

    2014-01-01

    Full Text Available The pharmacokinetic profile of cefepime (10 mg/kg b.w. was studied following intravenous and intramuscular administration of cefepime alone and coadministered with flunixin (2.2 mg/kg b.w. in goats. Cefepime concentrations in serum were determined by microbiological assay technique using Escherichia coli (MTCC 443 as test organism. Following intravenous injection of cefepime alone and in combination with flunixin, there are no significant changes in the pharmacokinetic parameters. Following intramuscular injection of cefepime alone and in combination with flunixin, the maximum serum concentration was significantly increased in flunixin coadministered group compared with cefepime alone. However, no significant changes were reported in other pharmacokinetic parameters. The result of in vitro protein binding study indicated that 15.62% of cefepime was bound to goat’s serum protein. The mean bioavailability was 92.66% and 95.27% in cefepime alone and coadministered with flunixin, respectively. The results generated from the present study suggest that cefepime may be coadministered with flunixin without change in dose regimen. Cefepime may be given intramuscularly at 12 h intervals to combat susceptible bacterial infections.

  3. 19 CFR 12.150 - Merchandise prohibited by economic sanctions; detention; seizure or other disposition; blocked...

    Science.gov (United States)

    2010-04-01

    ...; detention; seizure or other disposition; blocked property. 12.150 Section 12.150 Customs Duties U.S. CUSTOMS...; detention; seizure or other disposition; blocked property. (a) Generally. Merchandise from certain countries... the United States shall be detained until the question of its release, seizure, or other disposition...

  4. Critical Thinking Dispositions of Undergraduate Nursing Students and Nursing Faculty in Southwestern Nigeria

    Science.gov (United States)

    Ojewole, Foluso O.

    2013-01-01

    The purpose of this quantitative research study was to identify the critical thinking dispositions of undergraduate nursing students and nursing faculty in Southwestern Nigeria. Critical thinking dispositions are required for critical thinking skills. People who have critical thinking disposition exhibit seven traits: truth-seeking,…

  5. Contributions of Teachers' Thinking Styles to Critical Thinking Dispositions (Istanbul-Fatih Sample)

    Science.gov (United States)

    Emir, Serap

    2013-01-01

    The main purpose of the research was to determine the contributions of the teachers' thinking styles to critical thinking dispositions. Hence, it is aimed to determine whether thinking styles are related to critical thinking dispositions and thinking styles measure critical thinking dispositions or not. The research was designed in relational…

  6. 36 CFR 1225.26 - How do agencies change a disposition authority?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false How do agencies change a... disposition authority? Agencies must submit an SF 115 to permanently change the approved disposition of records. Disposition authorities are automatically superseded by approval of a later SF 115 for the same...

  7. Down the Rabbit Hole: Challenges and Methodological Recommendations in Researching Writing-Related Student Dispositions

    Science.gov (United States)

    Driscoll, Dana Lynn; Gorzelsky, Gwen; Wells, Jennifer; Hayes, Carol; Jones, Ed; Salchak, Steve

    2017-01-01

    Researching writing-related dispositions is of critical concern for understanding writing transfer and writing development. However, as a field we need better tools and methods for identifying, tracking, and analyzing dispositions. This article describes a failed attempt to code for five key dispositions (attribution, self-efficacy, persistence,…

  8. 17 CFR 200.42 - Disposition of business by seriatim Commission consideration.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Disposition of business by... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.42 Disposition of business by seriatim Commission consideration. (a) Whenever the...

  9. 17 CFR 200.40 - Joint disposition of business by Commission meeting.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Joint disposition of business... EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.40 Joint disposition of business by Commission meeting. Any meeting of the...

  10. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Disposition of business by... Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated to...

  11. The interaction between motivational disposition and participative budgeting

    DEFF Research Database (Denmark)

    Sandalgaard, Niels; Bukh, Per Nikolaj; Poulsen, Carsten Stig

    2011-01-01

    The purpose of the paper is to report the findings of a study of how dispositional factors of motivation rooted in personality interact with participative budgeting to affect budget goal commitment. The results indicate that the effect of increased budgetary participation on budget goal commitmen...

  12. Oppressors or Emancipators: Critical Dispositions for Preparing Inclusive School Leaders

    Science.gov (United States)

    Theoharis, George; Causton-Theoharis, Julie N.

    2008-01-01

    Leadership from school administrators is essential in creating inclusive schools. The purpose of this article is to outline the dispositions necessary for school leaders in order to develop and maintain inclusive educational services for all students. This work comes from a qualitative study of university-based experts who teach courses in…

  13. Influence Of Sexuality Education On The Behavioural Disposition Of ...

    African Journals Online (AJOL)

    The study investigated the influence of sexuality education on the behavioural disposition of Nigerian adolescents and its implications for counselling. The study employed a descriptive survey design. The participants included two hundred adolescents randomly selected from ten secondary schools in Lagos State.

  14. Dispositional Resistance to Change and Occupational Interests and Choices

    Science.gov (United States)

    Oreg, Shaul; Nevo, Ofra; Metzer, Hila; Leder, Naftali; Castro, Dotan

    2009-01-01

    Through two field studies, we examine the role that individuals' orientation toward change has in determining their occupational choices and interests. In Study 1, 139 job applicants' dispositional resistance to change (RTC) scores were associated with occupational choice, such that individuals applying for investigative and enterprising jobs…

  15. 19 CFR 123.25 - Certification and disposition of manifests.

    Science.gov (United States)

    2010-04-01

    ...; DEPARTMENT OF THE TREASURY CUSTOMS RELATIONS WITH CANADA AND MEXICO Shipments in Transit Through Canada or... required when the merchandise is to be transshipped in Canada or Mexico under Customs supervision shall be... 19 Customs Duties 1 2010-04-01 2010-04-01 false Certification and disposition of manifests. 123.25...

  16. College Student Disposition and Academic Self-Efficacy

    Science.gov (United States)

    Conner, Timothy W., II; Skidmore, Ronald L.; Aagaard, Lola

    2012-01-01

    Dispositional optimism is an adopted orientation in which one believes that goals will generally be attained and that tasks can generally be successfully completed, whereas pessimists orient toward less belief in successful task or goal completion. A related concept, individuals with high self-efficacy believe they will be successful at particular…

  17. Writing Pedagogies of Empathy: As Rhetoric and Disposition

    Science.gov (United States)

    Leake, Eric

    2016-01-01

    Empathy is attracting increased attention within and beyond the academy. In this essay I review relevant theories of empathy and their place within rhetoric and composition. I propose two approaches to teaching empathy: as rhetoric and as disposition. A rhetorical approach incorporates a necessary critical awareness of empathy's enticements and…

  18. Variables Impacting Dispositional Empathy in Doctoral Psychology Students

    Science.gov (United States)

    Micheli, Amelia C.

    2014-01-01

    The purpose of this study was to explore variables impacting dispositional empathy in doctoral psychology students. While there is a great deal of research regarding empathy in practicing psychologists and mental health professionals, little is known about empathy in psychology trainees. This is especially surprising given the importance of…

  19. Contribution of Emotional Intelligence towards Graduate Students' Critical Thinking Disposition

    Science.gov (United States)

    Kang, Fong-Luan

    2015-01-01

    Good critical thinkers possess a core set of cognitive thinking skills, and a disposition towards critical thinking. They are able to think critically to solve complex, real-world problems effectively. Although personal emotion is important in critical thinking, it is often a neglected issue. The emotional intelligence in this study concerns our…

  20. RA – beskeden genetisk disposition - resultater fra nyt dansk tvillingstudie

    DEFF Research Database (Denmark)

    Svendsen, Anders Jørgen

    2010-01-01

    undersøgelse af RA hos danske tvillinger underbygger vores tidligere observationer, der indikerer, at den genetiske disposition til den gruppe af polyartritter, der samles under betegnelsen reumatoid arthrit, er beskeden. De senere års forskning tyder på, at sygdommen i klinisk, behandlingsmæssig, men også i...

  1. Connecting the dots: exploring dispositions in teacher education ...

    African Journals Online (AJOL)

    The purpose of this study is to explore the dispositions that pre-service teachers require in order to be effective practitioners. Pre-service teachers study a curriculum that equips them with the content, as well as the pedagogical, psychological and philosophical knowledge, that are foundational to their tasks as both ...

  2. Preparing Students for a Diverse Workplace: Strategies to Improve Dispositions

    Science.gov (United States)

    Melton, Deana; Dail, Teresa

    2010-01-01

    The curriculum for kinesiology students typically includes foundation courses focused on the scientific principles underlying human movement. Modifications for gender, age, and physical ability are also commonly included in these courses. Rarely addressed, however, are students' dispositions toward diverse groups. This article examines several…

  3. 22 CFR 128.10 - Disposition of proceedings.

    Science.gov (United States)

    2010-04-01

    ....10 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS ADMINISTRATIVE PROCEDURES § 128.10 Disposition of proceedings. Where the evidence is not sufficient to support the charges... provided in § 127.7 of this subchapter, impose a civil penalty as provided in § 127.10 of this subchapter...

  4. Cultivating Critical-Thinking Dispositions throughout the Business Curriculum

    Science.gov (United States)

    Bloch, Janel; Spataro, Sandra E.

    2014-01-01

    Critical thinking is an essential component of managerial literacy, yet business school graduates struggle to apply critical-thinking skills at work to the level that employers desire. This article argues for a dispositional approach to teaching critical thinking, rooted in cultivating a critical-thinking culture. We suggest a two-pronged approach…

  5. Comprehensions on the dispositive: from information towards profanation

    Directory of Open Access Journals (Sweden)

    Jackson da Silva Medeiros

    2017-10-01

    Full Text Available Introduction: The knowledge communication can be seen in epistemological and institutional conditions of informational cycle mediation, acting as an intervener in the social construction of knowledge, controlled by explicit or implicit rules that awaken or bar the flow of knowledge. Objective: Explore and reflect on dispositive based on the idea that truth is based on actions and practices contextually specific, aiming to discuss and contribute to a systematization of “document” and “information”, understanding and strategizing about power relations. Methodology: Readings and interpretations on dispositive, as presented by Michel Foucault and later interpreted and worked by other authors, undertaking its construction in the conceptual body of information and of document for scientific knowledge access. Results and Conclusions: Still partial, the results point in the direction that dispositives that use the information and the document operate in the control and in the strategies of regulation of the power in the communication of the scientific information. Knowing that scientific knowledge is a construction of a truth, being validated within a community, needing the look on dispositives that desecration the sacred.

  6. On the dimensionality of the Dispositional Hope Scale

    NARCIS (Netherlands)

    Brouwer, Danny; Meijer, Rob R.; Weekers, Anke M.; Baneke, Joost J.

    The Dispositional Hope Scale (DHS; C. R. Snyder et al., 1991) consists of two subsets of items measuring Agency and Pathways. ne authors used bifactor analysis to evaluate the dimensionality structure of the scale. Data from 676 persons (295 psychiatric patients, 112 delinquents, and 269 students)

  7. 42 CFR 67.16 - Evaluation and disposition of application.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Evaluation and disposition of application. 67.16 Section 67.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING AGENCY FOR HEALTH CARE POLICY AND RESEARCH GRANTS AND CONTRACTS Research Grants for...

  8. The Changed Role Of Reference Librarian By Cultural Disposition ...

    African Journals Online (AJOL)

    A concept paper devoted to highlight the effects of cultural disposition of four distinct sets of cultural categories namely: hierarchical, individualistic, egalitarian and fatalistic users of library on reference librarian. The paper critically reviewed the information users' behavioural dimensions to reference services based on ...

  9. 7 CFR 984.56 - Disposition of reserve walnuts.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Board may export or authorize the disposition in export to the destinations outside the United States... marketing year a handler may deliver reserve walnuts and any substandard walnuts meeting the minimum kernel...

  10. 7 CFR 51.44 - Disposition of fees.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Schedule of Fees and Charges at Destination Markets § 51.44 Disposition of fees. (a) The fees collected for...

  11. Dispositional optimism, self-framing and medical decision-making.

    Science.gov (United States)

    Zhao, Xu; Huang, Chunlei; Li, Xuesong; Zhao, Xin; Peng, Jiaxi

    2015-03-01

    Self-framing is an important but underinvestigated area in risk communication and behavioural decision-making, especially in medical settings. The present study aimed to investigate the relationship among dispositional optimism, self-frame and decision-making. Participants (N = 500) responded to the Life Orientation Test-Revised and self-framing test of medical decision-making problem. The participants whose scores were higher than the middle value were regarded as highly optimistic individuals. The rest were regarded as low optimistic individuals. The results showed that compared to the high dispositional optimism group, participants from the low dispositional optimism group showed a greater tendency to use negative vocabulary to construct their self-frame, and tended to choose the radiation therapy with high treatment survival rate, but low 5-year survival rate. Based on the current findings, it can be concluded that self-framing effect still exists in medical situation and individual differences in dispositional optimism can influence the processing of information in a framed decision task, as well as risky decision-making. © 2014 International Union of Psychological Science.

  12. Dispositional and Situational Autonomy as Moderators of Mood and Creativity

    Science.gov (United States)

    Xiao, Fengqiu; Wang, Ling; Chen, Yinghe; Zheng, Zhiwei; Chen, Wenjun

    2015-01-01

    Although previous research suggests that mood can influence creativity, the controversy about the effects of positive and negative moods has raged for years. This study investigated how the relationship between induced mood and creativity is moderated by dispositional and situational autonomy. It contrasted the different moderating effects of the…

  13. The Missing Link: Teaching the Dispositions to Lead

    Science.gov (United States)

    Allen, James G.; Wasicsko, M. Mark; Chirichello, Michael

    2014-01-01

    In this article the authors contend that the element that is typically missing or underdeveloped in the education and development of most leaders is the intentional integration of the research and practices for assessing and developing the deeply held core beliefs, attitudes, and values (what we will call leadership dispositions) that play a…

  14. 5 CFR 293.405 - Disposition of records.

    Science.gov (United States)

    2010-01-01

    ... RECORDS Employee Performance File System Records § 293.405 Disposition of records. (a) When the OPF of a... the National Personnel Records Center, the “losing” servicing office shall include in the OPF all... prescribed in part 430 of this chapter. Also, the “losing” office will purge from the OPF all performance...

  15. Gender-related differences in attitudinal disposition of university ...

    African Journals Online (AJOL)

    Two research hypotheses were posed and tested using t-test statistic. The results indicated that there were no significant gender differences in the participants‟ attitudinal disposition to using mediation process to resolving conflict (t-cal =2.76; t-cri =1.96; df =253, P>0.05) and in their preference to resolving only conflict ...

  16. Comparing Teacher Dispositions in China and the USA

    Science.gov (United States)

    Shao, Kun; Tamashiro, Roy

    2013-01-01

    In studies conducted in the USA, teacher dispositional factors such as enthusiasm, professional esteem and learning motivation often emerge as the most significant variables affecting student learning and achievement from the primary grades through higher education. Do these factors play as significant a role in student learning and achievement in…

  17. Helping behavior, dispositional empathic concern, and the principle of care

    NARCIS (Netherlands)

    Wilhelm, M.O.; Bekkers, R.H.F.P.

    2010-01-01

    This research investigates the relative strength of two correlates of helping behavior: dispositional empathic concern and a moral principle to care about others. The empathy–helping and care–helping relationships are investigated using data from the General Social Survey, a nationally

  18. Consistency and Development of Prosocial Dispositions: A Longitudinal Study.

    Science.gov (United States)

    Eisenberg, Nancy; Guthrie, Ivanna K.; Murphy, Bridget C.; Shepard, Stephanie A.; Cumberland, Amanda; Carol, Gustavo

    1999-01-01

    Examined consistency in prosocial dispositions, using longitudinal data from preschool through early adulthood. Found that spontaneous prosocial behavior observed in preschools predicted actual prosocial behavior, other- and self-reported prosocial behavior, self-reported sympathy, and perspective taking in childhood to early adulthood. Prosocial…

  19. The disposition of distance learners towards success in their first ...

    African Journals Online (AJOL)

    The results indicated that few days before the examination respondents had occasional memory loss and the phenomenon of forgetting easily (mean of 1.55). Also, the night before their first paper ... expected frequencies were very highly significant. KEY WORDS: Disposition, anxiety, stress, Winneba, examination, centre.

  20. Adding dispositions to create pedagogy-based Learning Analytics

    NARCIS (Netherlands)

    Tempelaar, Dirk; Rienties, Bart; Nguyen, Quan

    This empirical study aims to demonstrate how Dispositional Learning Analytics (DLA) can provide a strong connection between Learning Analytics (LA) and pedagogy. Where LA based models typically do well in predicting course performance or student drop-out, they lack actionable data in order to easily

  1. 78 FR 18234 - Demolition or Disposition of Public Housing Projects

    Science.gov (United States)

    2013-03-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Part 970 Demolition or Disposition of Public Housing Projects CFR Correction 0 In Title 24 of the Code of Federal Regulations, Parts 700 to 1699, revised as of April 1, 2012, on page 490, in Sec. 970.27, redesignate paragraph ...

  2. Deconstructing Dispositions: Toward a Critical Ability Theory in Teacher Education

    Science.gov (United States)

    Bialka, Christa S.

    2015-01-01

    When attending to dispositions, or educators' assumptions and beliefs about teaching, learning, and students, teacher educators must develop a discourse that examines disability in terms of power and privilege. This article synthesizes literature related to critical race theory (CRT) and disability theory to elucidate the need for a critical…

  3. 30 CFR 879.15 - Disposition of reclaimed land.

    Science.gov (United States)

    2010-07-01

    ..., OSM, State, or Indian tribe shall publish a notice of proposed land disposition, hold public hearings... for land acquired by OSM to any State or Indian tribe or to any agency or political subdivision of a... any State or political subdivision of a State, to an Indian tribe, or to any firm, association, or...

  4. The Effect of Information Literacy on Teachers' Critical Thinking Disposition

    Science.gov (United States)

    Saglam, Aycan Çiçek; Çankaya, Ibrahim; Üçer, Hakan; Çetin, Muhammet

    2017-01-01

    The concepts of information literacy and critical thinking are two important concepts of today's information and technology age closely related to each other and sometimes used interchangeably. The purpose of the current study is to explore the relationship between the secondary school teachers' critical thinking disposition and information…

  5. Assessing personal disposition of individuals towards technology adoption

    Directory of Open Access Journals (Sweden)

    Irbha Magotra

    2016-06-01

    Full Text Available The present study has attempted to explore personal disposition of individuals towards technology adoption through the development of an index named as Technology Adoption Index. For developing the index, exploratory factor analysis approach has been employed on the sample of 1201 responses collected from the residents of 12 different cities in India. Accordingly, the results of the index have indicated significant role of seven personal traits, namely, optimism, innovativeness, self-efficacy, risk taking propensity, habit, social influence and psychological resilience while manifesting personal disposition of individuals towards technology adoption, i.e., the technology adoption propensity of the individuals. Further, an attempt has also been made to explore the socio-economic characteristics of the individuals possessing distinct level of personal disposition towards technology adoption. Accordingly, the results have unveiled that the personal disposition of the individuals towards technology adoption increases with enhancement in their income and qualification but decreases with enhancement in their age. As a measurement tool, Technology Adoption Index can be used as ready-recknor by practitioners for the identification of technology adoption propensity of the individuals. This will facilitate organizations in developing and designing new products and services which can be readily accepted by the individuals.

  6. 7 CFR 4285.69 - Evaluation and disposition of applications.

    Science.gov (United States)

    2010-01-01

    ... potential conflict of interest with the applicants. (2) Prior to technical examination, a preliminary review will be made for responsiveness to the program solicitation (e.g., relationship of proposal to research...-State Research on Cooperatives Program § 4285.69 Evaluation and disposition of applications. (a...

  7. Disposition Choices Based on Energy Footprints instead of Recovery Quota

    NARCIS (Netherlands)

    Krikke, H.R.; Zuidwijk, R.

    2008-01-01

    This paper addresses the impact of disposition choices on the energy use of closed-loop supply chains. In a life cycle perspective, energy used in the forward chain which is locked up in the product is recaptured in recovery. High quality recovery replaces virgin production and thereby saves energy.

  8. 7 CFR 993.150 - Disposition of prunes by handlers.

    Science.gov (United States)

    2010-01-01

    ... manifest or billing number; and (2) receive from the inspection service a DFA Form P-5 “Shipping Inspection...)(iii) of this section) the Committee's approval of his application to do so. (ii) Application for approval. The handler's application to ship or otherwise make final disposition of any such prunes shall be...

  9. Intelligent Dispositions: Dewey, Habits and Inquiry in Teacher Education

    Science.gov (United States)

    Nelsen, Peter J.

    2015-01-01

    Despite much debate in the literature, accrediting agencies continue to require that teacher education programs demonstrate that candidates possess requisite sets of dispositions deemed necessary for licensure. At least three unresolved and important questions remain unanswered that directly affect programs' abilities to do so: Are…

  10. Sweet vs. Snap! Effective Dispositions in the Media Center

    Science.gov (United States)

    Standard, April

    2011-01-01

    In "What Defines an Exemplary School Librarian," Jami Jones and Gail Bush make a strong argument that professional disposition is the key to a successful library media program. The authors emphasize the relevance of INTASC standards which specify that teachers must promote "positive social interaction and (develop) healthy and helping…

  11. Correlates of gratitude disposition in middle school students: gender differences.

    Science.gov (United States)

    Choi, Jung-hyun; Yu, Mi

    2014-01-01

    Gratitude disposition is positively associated with happiness. The purpose of this study was to identify influencing factors on gratitude disposition by gender differences in middle school students. Cross-sectional study using self-reported questionnaires were administered to participants (n=372) aged between 13 ∼ 15 years in Seoul and Chungnam Province in Korea. The collected data were analyzed with SPSS18.0 statistical program, and frequency analysis and logistic regression analysis were used in the research. The mean score of family abuse of boys was significantly higher than girls' score (t=3.016, p=0.003). In subscales of development assets, empowerment (t=2.264, p=0.024), boundaries and expectation (t=2.476, p=0.014), and commitment to learning (t=1.971, p=0.049) were significantly higher in boys. The results of logistic regression analysis showed that age (OR 0.334, CI 0.130∼0.862), peer relationship (OR 2.280, CI 1.124∼4.623), social support (OR 2.584, CI 1.176∼5.676), positive identity (OR 3.138, CI 1.256∼7.840) were significantly associated with gratitude disposition for boys, while school violence (OR 0.050, CI 0.003∼0.907) and positive identity (OR 2.937, CI 1.313∼6.567) were significantly associated with gratitude disposition for girls. This study suggests that it is important to protect adolescents from family abuse and school violence, furthermore, developmental assets should be developed to increase to gratitude disposition.

  12. The emergency department prediction of disposition (EPOD) study.

    Science.gov (United States)

    Vaghasiya, Milan R; Murphy, Margaret; O'Flynn, Daniel; Shetty, Amith

    2014-11-01

    Emergency departments (ED) continue to evolve models of care and streaming as interventions to tackle the effects of access block and overcrowding. Tertiary ED may be able to design patient-flow based on predicted dispositions in the department. Segregating discharge-stream patients may help develop patient-flows within the department, which is less affected by availability of beds in a hospital. We aim to determine if triage nurses and ED doctors can predict disposition outcomes early in the patient journey and thus lead to successful streaming of patients in the ED. During this study, triage nurses and ED doctors anonymously predicted disposition outcomes for patients presenting to triage after their brief assessments. Patient disposition at the 24-h post ED presentation was considered as the actual outcome and compared against predicted outcomes. Triage nurses were able to predict actual discharges of 445 patients out of 490 patients with a positive predictive value (PPV) of 90.8% (95% CI 87.8-93.2%). ED registrars were able to predict actual discharges of 85 patients out of 93 patients with PPV of 91.4% (95% CI 83.3-95.9%). ED consultants were able to predict actual discharges of 111 patients out of 118 patients with PPV 94.1% (95% CI 87.7-97.4%). PPVs for admission among ED consultants, ED registrars and Triage nurses were 59.7%, 54.4% and 48.5% respectively. Triage nurses, ED consultants and ED registrars are able to predict a patient's discharge disposition at triage with high levels of confidence. Triage nurses, ED consultants, and ED registrars can predict patients who are likely to be admitted with equal ability. This data may be used to develop specific admission and discharge streams based on early decision-making in EDs by triage nurses, ED registrars or ED consultants. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  13. Enzyme kinetics in drug metabolism: fundamentals and applications.

    Science.gov (United States)

    Nagar, Swati; Argikar, Upendra A; Tweedie, Donald J

    2014-01-01

    Enzymes are protein catalysts that lower the energy barrier for a reaction and speed the rate of a chemical change. The kinetics of reactions catalyzed by enzymes, as well as several mechanisms underlying the kinetics, have been comprehensively studied and written in textbooks (1, 2). The importance of quantitative evaluation of enzymatic processes has been recognized in many fields of study, including biochemistry, molecular biology, and pharmaceutical sciences to name a few. In pharmaceutical sciences, the applications of enzyme kinetics range from hit finding efforts for new chemical entities on a pharmacological target to concentration effect relationships to large-scale biosynthesis. The study of the science of drug metabolism has two principal concepts-rate and extent. While understanding disposition pathways and identification of metabolites provides an insight into the extent of metabolism, kinetics of depletion of substrates (endogenous or exogenous) and formation of metabolites deals with the rate of metabolism. The current textbook specifically focuses on kinetics of drug-metabolizing enzymes, detailing specific enzyme classes, and discusses kinetics as they apply to drug transporters. This textbook also outlines additional factors that contribute to the kinetics of reactions catalyzed by these proteins such as variability in isoforms (pharmacogenomics) and experimental factors including key concepts such as alterations of substrate concentrations due to binding. Applications of these approaches in predicting kinetic parameters and alternative approaches for enzymes (systems biology) and transporters are also discussed. The final section focuses on real-life examples (case studies) to try and exemplify the applications of enzyme kinetic principles. This chapter provides a brief overview outlining some key concepts within each of the sections and the chapters within this textbook.

  14. Measuring Dispositional Flow: Validity and reliability of the Dispositional Flow State Scale 2, Italian version.

    Directory of Open Access Journals (Sweden)

    Eleonora F M Riva

    Full Text Available The aim of this study is to evaluate the psychometric properties of the Italian version of the Dispositional Flow Scale-2 (DFS-2, for use with Italian adults, young adults and adolescents.In accordance with the guidelines for test adaptation, the scale has been translated with the method of back translation. The understanding of the item has been checked according to the latest standards on the culturally sensitive translation. The scale thus produced was administered to 843 individuals (of which 60.69% female, between the ages of 15 and 74. The sample is balanced between workers and students. The main activities defined by the subjects allow the sample to be divided into three categories: students, workers, athletes (professionals and semi-professionals.The confirmatory factor analysis, conducted using the Maximum Likelihood Estimator (MLM, showed acceptable fit indexes. Reliability and validity have been verified, and structural invariance has been verified on 6 categories of Flow experience and for 3 subsamples with different with different fields of action. Correlational analysis shows significant high values between the nine dimensions.Our data confirmed the validity and reliability of the Italian DFS-2 in measuring Flow experiences. The scale is reliable for use with Italian adults, young adults and adolescents. The Italian version of the scale is suitable for the evaluation of the subjective tendency to experience Flow trait characteristic in different contest, as sport, study and work.

  15. Disposition of levetiracetam in healthy adult horses.

    Science.gov (United States)

    Cesar, F B; Stewart, A J; Boothe, D M; Ravis, W R; Duran, S H; Wooldridge, A A

    2018-02-01

    Nine horses received 20 mg/kg of intravenous (LEVIV ); 30 mg/kg of intragastric, crushed immediate release (LEVCIR ); and 30 mg/kg of intragastric, crushed extended release (LEVCER ) levetiracetam, in a three-way randomized crossover design. Crushed tablets were dissolved in water and administered by nasogastric tube. Serum samples were collected over 48 hr, and levetiracetam concentrations were determined by immunoassay. Mean ± SD peak concentrations for LEVCIR and LEVCER were 50.72 ± 10.60 and 53.58 ± 15.94 μg/ml, respectively. The y-intercept for IV administration was 64.54 ± 24.99 μg/ml. The terminal half-life was 6.38 ± 1.97, 7.07 ± 1.93 and 6.22 ± 1.35 hr for LEVCIR , LEVCER, and LEVIV , respectively. Volume of distribution at steady-state was 630 ± 73.4 ml/kg. Total body clearance after IV administration was 74.40 ± 19.20 ml kg-1  hr-1 . Bioavailability was 96 ± 10, and 98 ± 13% for LEVCIR and LEVCER , respectively. A single dose of Levetiracetam (LEV) was well tolerated. Based on this study, a recommended dosing regimen of intravenous or oral LEV of 32 mg/kg every 12 hr is likely to achieve and maintain plasma concentrations within the therapeutic range suggested for humans, with optimal kinetics throughout the dosing interval in healthy adult horses. Repeated dosing and pharmacodynamic studies are warranted. © 2017 John Wiley & Sons Ltd.

  16. The role of dispositional and situational factors in cognitive interference.

    Science.gov (United States)

    Pierce, G R; Ptacek, J T; Taylor, B; Yee, P L; Henderson, C A; Lauventi, H J; Bourdeau, C M

    1998-10-01

    Two studies investigated the cross-temporal stability and cross-situational consistency of cognitive interference. In Study 1, 70 college students reported on the intrusive thoughts they experienced during 2 course examinations and a self-reflective task. In Study 2, 55 college athletes reported on intrusive thoughts following 2 course examinations and 2 regular season football games. Major findings were (a) cognitive interference showed both cross-temporal stability and cross-situational consistency, (b) it was predicted by a measure of dispositional intrusive thinking, (c) the link between cognitive interference and dispositional intrusive thinking was not accounted for by indices of depressive symptomatology and trait anxiety, and (d) the degree of cross-situational consistency of cognitive interference and the content of these intrusive thoughts were influenced by situational factors.

  17. Optimum Disposition of Metal Particles in the Propellant Grain

    Directory of Open Access Journals (Sweden)

    Leonid L. Minkov

    2014-01-01

    Full Text Available Using the dispersed metal in solid propellants to increase the temperature of combustion products leads to such a problem as the specific impulse loss due to the incomplete combustion of metal particles in the exhaust products. A redistribution of metal loaded into the propellant grain is one of the methods to decrease the specific impulse loss. This paper reports on the ways to obtain the optimum metal particle disposition for the case-bounded propellant grain of tube cross-sectional type. Three different approaches to analyze the metal combustion efficiency are discussed. The influence of the dynamic nonequilibrium of two-phase flow on the optimum metal particles disposition in the propellant grain of tube cross-sectional type is investigated.

  18. Strengthening maths learning dispositions through ‘math clubs’

    Directory of Open Access Journals (Sweden)

    Mellony Graven

    2016-02-01

    Full Text Available In this paper, I argue that the establishment of after-school mathematics clubs in early grades holds rich potential for supporting the development of increasingly participatory and sensemaking maths learning dispositions. Within the South African Numeracy Chair project, lead by the author, multiple after-school mathematics clubs have been set up for learners in Grades 3–6 across Eastern Cape schools. These clubs are a complementary initiative to teacher development, aimed at improving low levels of numeracy learning across the majority of schools in the province. Two sources of data, learner interviews and teacher questionnaires, from one case study club, are shared in this article to illuminate the potential such clubs hold in developing increasingly participatory mathematics learning dispositions.

  19. Music and Emotion: the Dispositional or Arousal theory

    Directory of Open Access Journals (Sweden)

    Alessandra Buccella

    2012-05-01

    Full Text Available One of the ways of analysing the relationship between music and emotions in through musical expressiveness.As the theory I discuss in this paper puts it, expressiveness in a particular kind of music's secondary quality or, to use the term which gives the theory its name, a disposition of music to arouse a certain emotional response in listeners.The most accurate version of the dispositional theory is provided by Derek Matravers in his book Art and Emotion and in other papers: what I will try to do, then, is to illustrate Matravers theory and claim that it is a good solution to many problems concerning music and its capacity to affect our inner states.

  20. First-year university students’ disposition and approaches to learning

    Directory of Open Access Journals (Sweden)

    María Victoria Pérez Villalobos

    2011-05-01

    Full Text Available Research on self-regulated learning has recognized cognitive processes that students select and execute to achieve their goals. When performing a task, the student analyzes the task characteristics, context and his own capacities, employing resource planning and management, adopting either deep or superficial learning approaches. To describe the relationship between “disposition to learning strategies and” and “deep and superficial learning approaches”, the “Cuestionario de Formas de Estudio” questionnaire was applied to 344 1st year students from eight study programs of a Chilean university. The results show significant correlation (r greater than 0.30, p lower than 0.001 between disposition to learning strategies and usage ofdeep learning approaches, and between the aforementioned variables andthe amount of weekly study time.

  1. Plutonium disposition via immobilization in ceramic or glass

    Energy Technology Data Exchange (ETDEWEB)

    Gray, L.W.; Kan, T.; Shaw, H.F.; Armantrout, A.

    1997-03-05

    The management of surplus weapons plutonium is an important and urgent task with profound environmental, national, and international security implications. In the aftermath of the Cold War, Presidential Policy Directive 13, and various analyses by renown scientific, technical, and international policy organizations have brought about a focused effort within the Department of Energy to identify and implement paths for the long term disposition of surplus weapons- usable plutonium. The central goal of this effort is to render surplus weapons plutonium as inaccessible and unattractive for reuse in nuclear weapons as the much larger and growing stock of plutonium contained in spent fuel from civilian reactors. One disposition option being considered for surplus plutonium is immobilization, in which the plutonium would be incorporated into a glass or ceramic material that would ultimately be entombed permanently in a geologic repository for high-level waste.

  2. Update of the used fuel disposition Campaign Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); MacKinnon, Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); McMahon, Kevin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Saltzstein, Sylvia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sorenson, Ken [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Swift, Peter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-09-01

    This Campaign Implementation Plan provides summary level detail describing how the Used Fuel Disposition Campaign (UFDC) supports achievement of the overarching mission and objectives of the Department of Energy Office of Nuclear Energy Fuel Cycle Technologies Program The implementation plan begins with the assumption of target dates that are set out in the January 2013 DOE Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste (http://energy.gov/downloads/strategy-management-and-disposal-used-nuclear-fuel-and-high-level-radioactive-waste). These target dates and goals are summarized in section III. This implementation plan will be maintained as a living document and will be updated as needed in response to progress in the Used Fuel Disposition Campaign and the Fuel Cycle Technologies Program.

  3. Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges.

    Science.gov (United States)

    Haque, Shadabul; Whittaker, Michael R; McIntosh, Michelle P; Pouton, Colin W; Kaminskas, Lisa M

    2016-08-01

    The inhaled delivery of nanomedicines can provide a novel, non-invasive therapeutic strategy for the more localised treatment of lung-resident diseases and potentially also enable the systemic delivery of therapeutics that are otherwise administered via injection alone. However, the clinical translation of inhalable nanomedicine is being hampered by our lack of understanding about their disposition and clearance from the lungs. This review provides a comprehensive overview of the biodegradable nanomaterials that are currently being explored as inhalable drug delivery systems and our current understanding of their disposition within, and clearance from the lungs. The safety of biodegradable nanomaterials in the lungs is discussed and latest updates are provided on the impact of inflammation on the pulmonary pharmacokinetics of inhaled nanomaterials. Overall, the review provides an in-depth and critical assessment of the lung clearance mechanisms for inhaled biodegradable nanomedicines and highlights the opportunities and challenges for their translation into the clinic. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Fundamental(ist) attribution error: Protestants are dispositionally focused.

    Science.gov (United States)

    Li, Yexin Jessica; Johnson, Kathryn A; Cohen, Adam B; Williams, Melissa J; Knowles, Eric D; Chen, Zhansheng

    2012-02-01

    Attribution theory has long enjoyed a prominent role in social psychological research, yet religious influences on attribution have not been well studied. We theorized and tested the hypothesis that Protestants would endorse internal attributions to a greater extent than would Catholics, because Protestantism focuses on the inward condition of the soul. In Study 1, Protestants made more internal, but not external, attributions than did Catholics. This effect survived controlling for Protestant work ethic, need for structure, and intrinsic and extrinsic religiosity. Study 2 showed that the Protestant-Catholic difference in internal attributions was significantly mediated by Protestants' greater belief in a soul. In Study 3, priming religion increased belief in a soul for Protestants but not for Catholics. Finally, Study 4 found that experimentally strengthening belief in a soul increased dispositional attributions among Protestants but did not change situational attributions. These studies expand the understanding of cultural differences in attributions by demonstrating a distinct effect of religion on dispositional attributions.

  5. Effect of Dispositional Traits on Pharmacy Students’ Attitude Toward Cheating

    Science.gov (United States)

    Saulsbury, Marilyn D.; Brown,, Ulysses J.; Heyliger, Simone O.

    2011-01-01

    Objective To explore the relation between dispositional traits and pharmacy students’ attitudes toward cheating in a university setting. Methods A questionnaire was administered primarily to pharmacy students at a comprehensive university in the southeastern United States to assess self-esteem, self-efficacy, idealism, relativism, student attitudes toward cheating, tolerance for peer cheating, detachment from the university, Machiavellian behavior, and demographic information. Results Gender, degree of idealism, relativism, and Machiavellian traits were found to influence student attitudes toward cheating, while age, grade-point average (GPA), race, income, and marital status did not. Conclusions Considered collectively, these data support the study model prediction that the major determinants of student attitudes toward cheating are based on the degree of idealism and relativism evident in the students’ dispositional trait. Idealism was found to be inversely related to the likelihood of a student engaging in cheating or tolerating peer cheating. PMID:21769145

  6. Effect of dispositional traits on pharmacy students' attitude toward cheating.

    Science.gov (United States)

    Saulsbury, Marilyn D; Brown, Ulysses J; Heyliger, Simone O; Beale, Ruby L

    2011-05-10

    To explore the relation between dispositional traits and pharmacy students' attitudes toward cheating in a university setting. A questionnaire was administered primarily to pharmacy students at a comprehensive university in the southeastern United States to assess self-esteem, self-efficacy, idealism, relativism, student attitudes toward cheating, tolerance for peer cheating, detachment from the university, Machiavellian behavior, and demographic information. Gender, degree of idealism, relativism, and Machiavellian traits were found to influence student attitudes toward cheating, while age, grade-point average (GPA), race, income, and marital status did not. Considered collectively, these data support the study model prediction that the major determinants of student attitudes toward cheating are based on the degree of idealism and relativism evident in the students' dispositional trait. Idealism was found to be inversely related to the likelihood of a student engaging in cheating or tolerating peer cheating.

  7. Positive Disposition in the Prediction of Strategic Independence among Millennials

    Directory of Open Access Journals (Sweden)

    Robert Konopaske

    2017-11-01

    Full Text Available Research on the dispositional traits of Millennials (born in 1980–2000 finds that this generation, compared to earlier generations, tends to be more narcissistic, hold themselves in higher regard and feel more entitled to rewards. The purpose of this intragenerational study is to counter balance extant research by exploring how the positive dispositional traits of proactive personality, core self-evaluation, grit and self-control predict strategic independence in a sample of 311 young adults. Strategic independence is a composite variable measuring a person’s tendency to make plans and achieve long-term goals. A confirmatory factor analysis and hierarchical regression found evidence of discriminant validity across the scales and that three of the four independent variables were statistically significant and positive predictors of strategic independence in the study. The paper discusses research and practical implications, strengths and limitations and areas for future research.

  8. Preliminary siting characterization Salt Disposition Facility - Site B

    Energy Technology Data Exchange (ETDEWEB)

    Wyatt, D.

    2000-01-04

    A siting and reconnaissance geotechnical program has been completed in S-Area at the Savannah River Site in South Carolina. This program investigated the subsurface conditions for the area known as ``Salt Disposition Facility (SDF), Site B'' located northeast of H-Area and within the S-Area. Data acquired from the Site B investigation includes both field exploration and laboratory test data.

  9. Age related differences in the disposition of acetanilide.

    Science.gov (United States)

    Playfer, J R; Baty, J D; Lamb, J; Powell, C; Price-Evans, D A

    1978-01-01

    1 The metabolism of fifteen elderly hospital in-patients and fifteen young people was studied, using a gas chromatography mass spectrometer method. 2 The results suggest that there is no significant change in hepatic oxidation of acetanilide with age. 3 The concentrations of metabolites were however, significantly elevated in the older group. 4 These results illustrate the importance of the decline in renal function with age in the disposition of drugs. PMID:728323

  10. MPC&A for plutonium disposition in the Russian federation

    Energy Technology Data Exchange (ETDEWEB)

    Sutcliffe, W.G.

    1995-08-08

    The issue of what to do with excess fissile materials from dismantled nuclear weapons has been discussed for a number of years. The options or alternatives commanding the most attention were identified by the American National Academy of Sciences. For plutonium these options are: (1) the fabrication and use of mixed-oxide (MOX) reactor fuel followed by the disposal of the spent fuel, or (2) vitrification (immobilization) of plutonium combined with highly radioactive material followed by direct disposal. The Academy report also identified the alternative of disposal in a deep borehole as requiring further study before being eliminated or accepted. The report emphasized security of nuclear materials as a principal factor in considering management and disposition decisions. Security of materials is particularly important in the near term-now-long before ultimate disposition can be accomplished. The MOX option was the subject of a NATO workshop held at Obninsk, Russia in October 1994. Hence this paper does not deal with the MOX alternative in detail. It deals with the following: materials protection, control, and accounting (MPC&A) for immobilization and disposal; the immobilization vs MOX alternatives; the security of disposed plutonium; the need to demonstrate MTC&A for plutonium disposition; and, finally, a recommended investment to quickly and inexpensively improve the protection of fissile materials in Russia. It is the author`s view that near-term management is of overriding importance. That is, with respect to the ultimate disposition of excess nuclear materials, how we get there is more important than where we are going.

  11. Three contextual frameworks for siblingships: nonlinear thinking, disposition, and phallocentrism.

    Science.gov (United States)

    Lament, Claudia

    2013-01-01

    This discussion of Juliet Mitchell's paper "Siblings: Thinking Theory" places her work within the context of three frameworks: nonlinear thinking, disposition, and phallocentrism. The nonlinear dimension of the developmental process demonstrates how the sibling experience is not static, but rather is subject to a natural transmogrification toward new adaptive forms and meanings that occur over the sequential progress of organizational growth. Secondly, dispositional variables tend to be overlooked in their role in how brothers and sisters engage one another, titrate closeness and separateness, and creatively live out their love, admiration, hate, envy, and rivalry with each other. Sensitivities in dispositional leanings, such as special empathic qualities, may even serve to mitigate sibling turbulence. Lastly, the phallocentricity in Western societies privileges an implicitly male perspective that envisions sibling relationships in terms of threatening competitors, as the common linguistic phrase sibling rivalry suggests. This inflection in culture disregards more-expanding qualities in object relationships and aim-giving strategies that are exchanged in sibling play. These variables are not the sole contributors to the sibling experience, but a sampling of influences both from within and outside the child that affect that experience.

  12. Inventory planning for feed metal production and excess materials disposition.

    Energy Technology Data Exchange (ETDEWEB)

    Hench, K. W. (Karen W.); Owens, S. D. (Sammi D.); Yarbro, T. F. (Tresa F.); Sena, D. J. (Diana J.); Mills, C. J. (Cindy J.)

    2001-01-01

    Inventory planning and scheduling at the Los Alamos National Laboratory nuclear facility (TA-55) has become increasingly demanding given the limited supply of nuclear materials available for weapons production. This limitation comes from the shutdown of nuclear production reactors as well as the declaration of materials excess to national security within the DOE complex. The materials that have been declared excess to national security cannot be used in support of nuclear weapons activities and must be appropriately dispositioned. The matrices of the excess materials and the materials in the weapons; stream are often similar, if not identical, and must be processed and/or packaged utilizing the same personnel and facility resources. In order to segregate these materials and continue weapons production and dispositioning operations concurrently, careful tracking at the item level is required. Scheduling and campaigning of these materials must also be carefully monitored in order to meet both nuclear weapons production schedules as well as dispositioning milestones. All planning activities must consider the impact of processing operations on severely constrained resources including the special nuclear materials storage vault, the nondestructive assay laboratory, and the waste management and shipping operations. This paper details the methodologies and the use of simulation and other computerized tools by the Nuclear Materials Technology Division materials management organization at TA-55. These tools assist in predicting materials and resource availability and optimizing the inventory planning activities.

  13. A critical thinking disposition scale for nurses: short form.

    Science.gov (United States)

    Hwang, Shiow-Y; Yen, Miaofen; Lee, Bih-O; Huang, Mei-C; Tseng, Hung-F

    2010-11-01

    The aim of this study was to test the Chinese version of the Critical Thinking Disposition Inventory (CTDI-CV) among nurses in Taiwan. Critical thinking is the use of purposeful self-regulatory judgments to identify patient's problems and provide patient care. Critical thinking influences nurses' decision making. To date, no inventory to understand nurse's critical thinking disposition has been developed. This was a survey design with a stratified random sampling to test the reliability and validity of the CTDI-CV. The participants comprised 864 registered nurses who were chosen by stratified random sampling from seven hospitals in Taiwan. Data were collected through self-administered structured questionnaires. A new scale, short form (SF) CTDI-CV, contains 18 items with three subscales: 'systematic analysis', 'thinking within the box' and 'thinking out of the box', was generated from the analysis with 44% explained variance. Cronbach's alpha coefficients and intra-class correlation coefficients for overall and subscale were above 0.8. Goodness-of-fit test for the final model of SF-CTDI-CV revealed an acceptable result in the overall fit (χ(2)/df = 4.04, p thinking disposition for nurses. A short and valid critical thinking instrument for nurses will facilitate critical thinking research in the clinical practice arena. When designing continuing education activities, clinical educators will be able to efficiently and effectively evaluate the quality of critical thinking among practicing nurses. © 2010 Blackwell Publishing Ltd.

  14. Stable isotope studies of nicotine kinetics and bioavailability

    Energy Technology Data Exchange (ETDEWEB)

    Benowitz, N.L.; Jacob, P. 3d.; Denaro, C.; Jenkins, R. (Univ. of California, San Francisco (USA))

    1991-03-01

    The stable isotope-labeled compound 3',3'-dideuteronicotine was used to investigate the disposition kinetics of nicotine in smokers, the systemic absorption of nicotine from cigarette smoke, and the bioavailability of nicotine ingested as oral capsules. Blood levels of labeled nicotine could be measured for 9 hours after a 30-minute intravenous infusion. Analysis of disposition kinetics in 10 healthy men revealed a multiexponential decline after the end of an infusion, with an elimination half-life averaging 203 minutes. This half-life was longer than that previously reported, indicating the presence of a shallow elimination phase. Plasma clearance averaged 14.6 ml/min/kg. The average intake of nicotine per cigarette was 2.29 mg. A cigarette smoke-monitoring system that directly measured particulate matter in smoke was evaluated in these subjects. Total particulate matter, number of puffs on the cigarette, total puff volume, and time of puffing correlated with the intake of nicotine from smoking. The oral bioavailability of nicotine averaged 44%. This bioavailability is higher than expected based on the systemic clearance of nicotine and suggests that there may be significant extrahepatic metabolism of nicotine.

  15. Potentially Avoidable Surgical Intensive Care Unit Admissions and Disposition Delays.

    Science.gov (United States)

    Dhillon, Navpreet K; Ko, Ara; Smith, Eric J T; Kharabi, Mayumi; Castongia, Joseph; Nurok, Michael; Gewertz, Bruce L; Ley, Eric J

    2017-11-01

    High health care costs encourage initiatives that avoid overuse of resources and identify opportunities to promote appropriate care. To investigate the causes of potentially avoidable surgical intensive care unit (SICU) admissions and disposition delays to determine whether targeted interventions could decrease these stays. This prospective, observational study focused on potentially avoidable SICU days, as determined by observers with input from the rounding intensivists at a 24-bed open SICU at an urban, academic hospital. The preintervention phase occurred from April 6 through June 21, 2015; after implementation of targeted interventions, the postintervention phase occurred from April 4 through June 28, 2016. Data collected included demographic characteristics, reason for admission, and length of stay. All patients admitted to the SICU during the preintervention and postintervention phases were included in the analysis. Based on results collected in the preintervention phase, targeted interventions were designed and implemented from July 1, 2015, through March 31, 2016, including (1) reducing SICU care for minor traumatic brain injury, (2) optimizing postoperative airway management, (3) enhancing communication between services regarding transfers to the SICU, (4) identifying and facilitating more timely end-of-life conversations and supportive care consultations, and (5) encouraging early disposition of patients to floor beds. Changes in the proportion of potentially avoidable SICU days owing to potentially avoidable admissions and/or disposition delays. A total of 459 patients (253 men [55.1%] and 206 women [44.9%]; median age, 62 years [interquartile range, 46-75 years]) were admitted during the preintervention and postintervention phases. Of 261 patients admitted during the preintervention period and 245 during the postintervention period, median SICU and hospital length of stay remained unchanged. A reduction was noted in the percentage of postintervention

  16. Disposition of amopyroquin in rats and rabbits and in vitro activity against Plasmodium falciparum.

    Science.gov (United States)

    Pussard, E; Verdier, F; Faurisson, F; Clavier, F; Simon, F; Gaudebout, C

    1988-04-01

    The disposition of amopyroquin was studied in rats after a single 50-mg/kg (body weight) oral dose of amopyroquin base. After a rapid absorption phase, the drug concentrations decreased in the plasma, with a terminal half-life of 14.5 h. The drug was widely distributed in the liver and lungs and, to a lesser extent, in the kidneys and spleen. In rabbits, the kinetic parameters were compared after a single 10-mg/kg dose of amopyroquin base through intravenous, intramuscular (i.m.), and oral routes. The similar bioavailability values (0.67 and 0.69) suggested that the drug could be used through i.m. or oral administration. Clearance and distribution volume did not differ significantly among the three modes of administration, and the terminal half-lives were 18.1 +/- 3.3, 23.9 +/- 6.7, and 25.7 +/- 5.4 h for intravenous, i.m., and oral routes, respectively. The ratio of concentrations in erythrocytes and plasma was about 5 in rats and rabbits. Three metabolites were detected in both animal species (one was tentatively identified as the primary amine derivative). The amopyroquin in vitro activity was tested against four chloroquine-susceptible and 11 chloroquine-resistant African Plasmodium falciparum strains. For all isolates, the 50% inhibitory concentrations of amopyroquin were much lower than those of chloroquine and monodesethylamodiaquine.

  17. Update to the Fissile Materials Disposition program SST/SGT transportation estimation

    Energy Technology Data Exchange (ETDEWEB)

    John Didlake

    1999-11-15

    This report is an update to ``Fissile Materials Disposition Program SST/SGT Transportation Estimation,'' SAND98-8244, June 1998. The Department of Energy Office of Fissile Materials Disposition requested this update as a basis for providing the public with an updated estimation of the number of transportation loads, load miles, and costs associated with the preferred alternative in the Surplus Plutonium Disposition Final Environmental Impact Statement (EIS).

  18. Relationship between critical thinking disposition and teaching efficacy among special education integration program teachers in Malaysia

    Science.gov (United States)

    Sulaiman, Tajularipin; a/l Kuppusamy, Suresh Kumar; Ayub, Ahmad Fauzi Mohd; Rahim, Suzieleez Syrene Abdul

    2017-01-01

    This study aims to assess the level of critical thinking disposition and teaching efficacy among the Special Education Integration Programme (SEIP) teachers in Negeri Sembilan, Malaysia. The level of critical thinking dispositions and teaching efficacy in the SEIP were compared based on teaching experience and gender. The study also examined the relationship between critical thinking disposition and teaching efficacy at SEIP. The research adopted a quantitative survey approach. A total of 190 primary school teachers from the SEIP in Negeri Sembilan were selected using proportional sampling method. The instrument used in this study comprised of three sections; demography, critical thinking disposition and teaching efficacy. Descriptive and inferential statistics were used in the analysis. Analysis shows that the respondents have a moderate level of critical thinking disposition (M = 2.99, S.D = 0.160) and teaching efficacy (M = 3.01 S.D. = 0.128) was at a high level. For teaching experience, the analysis showed that thinking disposition of novice teachers (mean = 2.52, SD = .503) are significantly higher than experienced teachers (mean = 2.35, SD = .481, t = 2.244, p <.05). There was no significant difference between male and female SEIP teachers in critical thinking disposition and teaching efficacy. Findings also indicated that there is a significant positive moderate relationship (r = .477) between critical thinking disposition and teaching efficacy among SEIP teachers. This study suggests that critical thinking disposition and teaching efficacy play an important role to enhance the performance of SEIP teachers.

  19. Critical Thinking Dispositions of Nursing Students in Asian and Non-Asian Countries: A Literature Review

    Science.gov (United States)

    Salsali, Mahvash; Tajvidi, Mansooreh; Ghiyasvandian, Shahrzad

    2013-01-01

    Critical thinking disposition represents an inclination of a person to use possessed skills in relation to critical thinking. The trend of critical thinking has been described as inner motivation to solve problems and make decisions by thinking. In nursing as a practical profession, the concept of critical thinking dispositions is important component in helping to manage complex health situations and to deal with patient issues effectively. Willingness to think critically is a prerequisite for safe and subtly performance. The results of studies show critical thinking dispositions of nursing students in Asian countries are different from non-Asian countries. Aim of this literature review was to compare critical thinking dispositions of nursing students in Asian and non-Asian countries. Literature review was done in English and Persian databases. The results showed of the 795 articles published in English and Persian language that studied critical thinking, 73 ones studied critical thinking skills and dispositions in nursing education, and relationship between teaching methods and critical thinking skills and dispositions in nursing education of different countries. Fifteen of seventy three articles assessed critical thinking dispositions in nursing students. Limited studies showed that the Asian nursing students had mostly undermining score of the critical thinking dispositions, while non-Asian countries tend to positive scores. The reasons for these differences could be due to issues such as environmental, educational methods and cultural differences. However, future studies should measure critical thinking disposition by discipline-based tools. PMID:24171885

  20. Visual, Critical, and Scientific Thinking Dispositions in a 3rd Grade Science Classroom

    Science.gov (United States)

    Foss, Stacy

    Many American students leave school without the required 21st century critical thinking skills. This qualitative case study, based on the theoretical concepts of Facione, Arheim, and Vygotsky, explored the development of thinking dispositions through the arts in science on the development of scientific thinking skills when used as a conceptual thinking routine in a rural 3rd grade classroom. Research questions examined the disposition to think critically through the arts in science and focused on the perceptions and experiences of 25 students with the Visual Thinking Strategy (VTS) process. Data were collected from classroom observations (n = 10), student interviews (n = 25), teacher interviews ( n = 1), a focus group discussion (n = 3), and artifacts of student work (n = 25); these data included perceptions of VTS, school culture, and classroom characteristics. An inductive analysis of qualitative data resulted in several emergent themes regarding disposition development and students generating questions while increasing affective motivation. The most prevalent dispositions were open-mindedness, the truth-seeking disposition, the analytical disposition, and the systematicity disposition. The findings about the teachers indicated that VTS questions in science supported "gradual release of responsibility", the internalization of process skills and vocabulary, and argumentation. This case study offers descriptive research that links visual arts inquiry and the development of critical thinking dispositions in science at the elementary level. A science curriculum could be developed, that emphasizes the development of thinking dispositions through the arts in science, which in turn, could impact the professional development of teachers and learning outcomes for students.

  1. Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion

    National Research Council Canada - National Science Library

    Modinos, Gemma; Ormel, Johan; Aleman, André

    2010-01-01

    .... Individual differences in dispositional mindfulness reflect differences in typical recognition, detachment and regulation of current experience, thought to also operate as top-down control mechanism...

  2. [The relationship study on the relationship between procrastination behaviors and bad personality disposition].

    Science.gov (United States)

    Wei, Yuan

    2006-01-01

    To explore the relationship between procrastinate behavior of college students and bad personality disposition. 566 college students were selected and followed through adopting the measurement on the procrastination scale of college students and Personality Disorders Questionnaire (PDQ-4). Results showed that male and female college students did not have remarkable difference in terms of procrastination. High level procrastinators had a higher level of scores on bad personality disposition. In addition, College students' procrastination had close relationship with bad personality disposition (r = 0.341, P procrastination had close relationship with bad personality disposition which did not match the findings from McCown's results on american college students.

  3. Critical thinking dispositions of nursing students in Asian and non-Asian countries: a literature review.

    Science.gov (United States)

    Salsali, Mahvash; Tajvidi, Mansooreh; Ghiyasvandian, Shahrzad

    2013-09-26

    Critical thinking disposition represents an inclination of a person to use possessed skills in relation to critical thinking. The trend of critical thinking has been described as inner motivation to solve problems and make decisions by thinking. In nursing as a practical profession, the concept of critical thinking dispositions is important component in helping to manage complex health situations and to deal with patient issues effectively. Willingness to think critically is a prerequisite for safe and subtly performance. The results of studies show critical thinking dispositions of nursing students in Asian countries are different from non-Asian countries. Aim of this literature review was to compare critical thinking dispositions of nursing students in Asian and non-Asian countries. Literature review was done in English and Persian databases. The results showed of the 795 articles published in English and Persian language that studied critical thinking, 73 ones studied critical thinking skills and dispositions in nursing education, and relationship between teaching methods and critical thinking skills and dispositions in nursing education of different countries. Fifteen of seventy three articles assessed critical thinking dispositions in nursing students. Limited studies showed that the Asian nursing students had mostly undermining score of the critical thinking dispositions, while non-Asian countries tend to positive scores. The reasons for these differences could be due to issues such as environmental, educational methods and cultural differences. However, future studies should measure critical thinking disposition by discipline-based tools.

  4. Principles of chemical kinetics

    CERN Document Server

    House, James E

    2007-01-01

    James House's revised Principles of Chemical Kinetics provides a clear and logical description of chemical kinetics in a manner unlike any other book of its kind. Clearly written with detailed derivations, the text allows students to move rapidly from theoretical concepts of rates of reaction to concrete applications. Unlike other texts, House presents a balanced treatment of kinetic reactions in gas, solution, and solid states. The entire text has been revised and includes many new sections and an additional chapter on applications of kinetics. The topics covered include quantitative rela

  5. Introduction to chemical kinetics

    CERN Document Server

    Soustelle, Michel

    2013-01-01

    This book is a progressive presentation of kinetics of the chemical reactions. It provides complete coverage of the domain of chemical kinetics, which is necessary for the various future users in the fields of Chemistry, Physical Chemistry, Materials Science, Chemical Engineering, Macromolecular Chemistry and Combustion. It will help them to understand the most sophisticated knowledge of their future job area. Over 15 chapters, this book present the fundamentals of chemical kinetics, its relations with reaction mechanisms and kinetic properties. Two chapters are then devoted to experimental re

  6. Evaluation of Possible Surrogates for Validation of the Oxidation Furnace for the Plutonium Disposition Project

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, A.

    2007-12-31

    The Plutonium Disposition project (PuD) is considering an alternative furnace design for direct metal oxidation (DMO) of plutonium metal to use as a feed for potential disposition routes. The proposed design will use a retort to oxidize the feed at temperatures up to 500 C. The atmosphere will be controlled using a metered mixture of oxygen, helium and argon to control the oxidation at approximately 400 torr. Since plutonium melts at 664 C, and may potentially react with retort material to form a lower melting point eutectic, the oxidation process will be controlled by metering the flow of oxygen to ensure that the bulk temperature of the material does not exceed this temperature. A batch processing time of <24 hours is desirable to meet anticipated furnace throughput requirements. The design project includes demonstration of concept in a small-scale demonstration test (i.e., small scale) and validation of design in a full-scale test. These tests are recommended to be performed using Pu surrogates due to challenges in consideration of the nature of plutonium and operational constraints required when handling large quantities of accountable material. The potential for spreading contamination and exposing workers to harmful levels of cumulative radioactive dose are motivation to utilize non-radioactive surrogates. Once the design is demonstrated and optimized, implementation would take place in a facility designed to accommodate these constraints. Until then, the use of surrogates would be a safer, less expensive option for the validation phase of the project. This report examines the potential for use of surrogates in the demonstration and validation of the DMO furnace for PuD. This report provides a compilation of the technical information and process requirements for the conversion of plutonium metal to oxide by burning in dry environments. Several potential surrogates were evaluated by various criteria in order to select a suitable candidate for large scale

  7. Institutional disposition and management of end-of-life electronics.

    Science.gov (United States)

    Babbitt, Callie W; Williams, Eric; Kahhat, Ramzy

    2011-06-15

    Institutions both public and private face a challenge to develop policies to manage purchase, use, and disposal of electronics. Environmental considerations play an increasing role in addition to traditional factors of cost, performance and security. Characterizing current disposition practices for end-of-life electronics is a key step in developing policies that prevent negative environmental and health impacts while maximizing potential for positive social and economic benefits though reuse. To provide a baseline, we develop the first characterization of quantity, value, disposition, and flows of end-of-life electronics at a major U.S. educational institution. Results of the empirical study indicate that most end-of-first-life electronics were resold through public auction to individuals and small companies who refurbish working equipment for resale or sell unusable products for reclamation of scrap metal. Desktop and laptop computers sold for refurbishing and resale averaged U.S. $20-100 per unit, with computers sold directly to individuals for reuse reaching $250-350 per unit. This detailed assessment was coupled with a benchmarking survey of end-of-life electronics management practices at other U.S. universities. Survey results indicate that while auctions are still commonplace, an increasing number of institutions are responding to environmental concerns by creating partnerships with local recycling and resale entities and mandating domestic recycling. We use the analyses of current disposition practices as input to discuss institutional strategies for managing electronics. One key issue is the tension between benefits of used equipment sales, in terms of income for the institution and increased reuse for society, and the environmental risks because of unknown downstream practices.

  8. CAMRAD - COMPUTER AIDED MATERIAL REVIEW AUTOMATED DISPOSITION SYSTEM

    Science.gov (United States)

    Hanna, T. L.

    1994-01-01

    The basic function of a manufacturer's production support engineering unit is to identify, document, and dispose of hardware that does not conform to drawing requirements. CAMRAD, a program designed for rapid input and retrieval of all data used in engineering-to-manufacturing support operations, aids the engineer by automating the material review disposition process. Before CAMRAD, material review record searches were manual. The time spent searching through old documents precluded the timely disposition of new material reviews. CAMRAD facilitates the research of material review histories and provides for the efficient processing of material review documents. Three SmartWare project files control the operation of CAMRAD. The project file CAMRAD initializes variables for the other project files and specifies the pathing of the CAMRAD program, database files, and document files. The project file DATARAD controls all data management functions. The database consists of individual files containing all records of specific hardware discrepancies for a given part number. There are four basic avenues for records searches: part serial number, feature, Material Review (MR) number, and non-conformance. WORDRAD is the project file which controls the management of document files created when processing a material review disposition. Given a material review report identifying a defective hardware item, the production support engineer can use CAMRAD to quickly search the database for any history of the same problem, find out how well the problem has been documented, and create appropriate documentation for this latest occurrence. CAMRAD is written in the Smart Programming Language and is designed to run on IBM PC compatibles with the SmartWare v. 3.1 software package available from Informix Software. CAMRAD was developed in 1987. SmartWare is a registered trademark of Informix Software, Inc. IBM PC is a registered trademark of International Business Machines Corporation.

  9. Spatial Kinetics Calculations of MOX Fueled Core: Variant 22

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovichev, A.M.

    2001-01-11

    This work is part of a Joint US/Russian Project with Weapons-Grade Plutonium Disposition in VVER Reactors and presents the results of spatial kinetics calculational benchmarks. The examinations were carried out with the following purposes: to verify one of spatial neutronic kinetics model elaborated in KI, to understand sensibility of the model to neutronics difference of UOX and MOX cores, to compare in future point and spatial kinetics models (on the base of a set of selected accidents) in view of eventual creation of RELAP option with 3D kinetics. The document contains input data and results of model operation of three emergency dynamic processes in the VVER-1000 core: central control rod ejection by pressure drop caused by destroying of the moving mechanism cover; overcooling of the reactor core caused by steam line rupture and non-closure of steam generator stop valve; and the boron dilution of coolant in part of the VVER-1000 core caused by penetration of the distillate slug into the core at start up of non-working loop.

  10. Disposition of plutonium-239 via production of fission molybdenum-99.

    Science.gov (United States)

    Mushtaq, A

    2011-04-01

    A heritage of physical consequences of the U.S.-Soviet arms race has accumulated, the weapons-grade plutonium (WPu), which will become excess as a result of the dismantlement of the nuclear weapons under the arms reduction agreements. Disposition of Pu has been proposed by mixing WPu with high-level radioactive waste with subsequent vitrification into large, highly radioactive glass logs or fabrication into mixed oxide fuel with subsequent irradiation in existing light water reactors. A potential option may be the production of medical isotope molybdenum-99 by using Pu-239 targets. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Disposition of plutonium-239 via production of fission molybdenum-99

    Energy Technology Data Exchange (ETDEWEB)

    Mushtaq, A., E-mail: muahtaq_a1953@hotmail.co [Isotope Production Division, Pakistan Institute of Nuclear Science and Technology, P.O. Nilore, Islamabad (Pakistan)

    2011-04-15

    A heritage of physical consequences of the U.S.-Soviet arms race has accumulated, the weapons-grade plutonium (WPu), which will become excess as a result of the dismantlement of the nuclear weapons under the arms reduction agreements. Disposition of Pu has been proposed by mixing WPu with high-level radioactive waste with subsequent vitrification into large, highly radioactive glass logs or fabrication into mixed oxide fuel with subsequent irradiation in existing light water reactors. A potential option may be the production of medical isotope molybdenum-99 by using Pu-239 targets.

  12. Supplement to the Surplus Plutonium Disposition Draft Environmental Impact Statement

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    1999-05-14

    On May 22, 1997, DOE published a Notice of Intent in the Federal Register (62 Federal Register 28009) announcing its decision to prepare an environmental impact statement (EIS) that would tier from the analysis and decisions reached in connection with the ''Storage and Disposition of Weapons-Usable Fissile Materials Final Programmatic EIS (Storage and Disposition PEIS)''. ''The Surplus Plutonium Disposition Draft Environmental Impact Statement'' (SPD Draft EIS) (DOWEIS-0283-D) was prepared in accordance with NEPA and issued in July 1998. It identified the potential environmental impacts of reasonable alternatives for the proposed siting, construction, and operation of three facilities for plutonium disposition. These three facilities would accomplish pit disassembly and conversion, immobilization, and MOX fuel fabrication. For the alternatives that included MOX fuel fabrication, the draft also described the potential environmental impacts of using from three to eight commercial nuclear reactors to irradiate MOX fuel. The potential impacts were based on a generic reactor analysis that used actual reactor data and a range of potential site conditions. In May 1998, DCE initiated a procurement process to obtain MOX fuel fabrication and reactor irradiation services. The request for proposals defined limited activities that may be performed prior to issuance of the SPD EIS Record of Decision (ROD) including non-site-specific work associated with the development of the initial design for the MOX fuel fabrication facility, and plans (paper studies) for outreach, long lead-time procurements, regulatory management, facility quality assurance, safeguards, security, fuel qualification, and deactivation. No construction on the proposed MOX facility would begin before an SPD EIS ROD is issued. In March 1999, DOE awarded a contract to Duke Engineering & Services; COGEMA, Inc.; and Stone & Webster (known as DCS) to provide the requested

  13. The Effects of Reflective Training on the Disposition of Critical Thinking for Nursing Students in China: A Controlled Trial

    National Research Council Canada - National Science Library

    Caihong Zhang; Huiying Fan; Jieqiong Xia; Honghua Guo; Xinjun Jiang; Yane Yan

    2017-01-01

    ... diaries but without a formal training. Before and after the intervention, nursing students' critical thinking disposition was rated using the Chinese version of Critical Thinking Disposition Inventory (CTDI-CV...

  14. Effectiveness of gratitude disposition promotion program on depression and quality of life of chronic schizophrenic patients.

    Science.gov (United States)

    Jung, Miran; Han, Kuemsun

    2017-01-01

    Gratitude intervention is expectedly an effective intervention to reduce depression and improve the quality of life in schizophrenic patients, but there is a lack of literature on it. We attempted to develop and test the effectiveness of the gratitude disposition promotion program for chronic schizophrenic patients in Korea. Nonequivalent control group pre- and post-test design was used in two mental health centers located at Gyeonggi-do in South Korea. This paper was a quasi-experimental study and the participants who took part in the gratitude disposition promotion program were 17 of experimental group and 15 of control group. Gratitude disposition (the short gratitude, resentment, and appreciation test), depression (Beck Depression Inventory), and quality of life (developed by Kook) of chronic schizophrenic patients were measured before and after an intervention, as compared to the control. Chi-square test, Fisher's exact test, and t -test were performed for prehomogeneity testing for variables related to the general characteristics. Testing for the effectiveness of gratitude disposition promotion program and hypothesis testing for its effect on depression and quality of life were by ANCOVA and t -test, as verified to significance level of P gratitude disposition promotion program showed significant improvements in gratitude disposition ( F = 18.740, P gratitude disposition promotion program was an effective clinical intervention program for enhancing gratitude disposition and quality of life of chronic schizophrenic patients in community.

  15. 9 CFR 354.142 - Food product inspection certificates; issuance and disposition.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Food product inspection certificates; issuance and disposition. 354.142 Section 354.142 Animals and Animal Products FOOD SAFETY AND INSPECTION... disposition. (a) Upon the request of an interested party, any inspector is authorized to issue a food product...

  16. Defense Logistics Agency Disposition Services Needs to Improve Demilitarization Program Self-Assessment Evaluations - Redacted

    Science.gov (United States)

    2016-12-20

    Defense Logistics Agency Disposition Services Needs to Improve Demilitarization Program Self ‑Assessment Evaluations Management Comments and Our...and control of the Compliance Assessment Management System (CAMS);9 • provide and coordinate protocols and instructions to the CDDs to complete self ...assessments; • notify DLA Disposition Services management of self -assessments results, repeat findings, suggested corrective actions, best practices

  17. Situational and Dispositional Factors as Antecedents of Ingratiatory Behaviors in Organizational Settings

    Science.gov (United States)

    Kacmar, K. Michele; Carlson, Dawn S.; Bratton, Virginia K.

    2004-01-01

    This study examined both situational and dispositional antecedents of four ingratiatory behaviors: other-enhancing, opinion conformity, favor rendering, and self-promotion. The two situational variables (i.e., role ambiguity and leader-member exchange) and the four dispositional variables (i.e., self-esteem, need for power, job involvement, and…

  18. Facilitating a Student-Educator Conceptual Model of Dispositions towards Critical Thinking through Interactive Management

    Science.gov (United States)

    Dwyer, Christopher P.; Hogan, Michael J.; Harney, Owen M.; Kavanagh, Caroline

    2017-01-01

    Critical thinking (CT) is a metacognitive process, consisting of a number of sub-skills and dispositions that, when used appropriately, increases the chances of producing a logical conclusion to an argument or solution to a problem. Though the CT literature argues that dispositions are as important to CT as is the ability to perform CT skills, the…

  19. Dispositional Optimism and the Risk of Cardiovascular Death : The Zutphen Elderly Study

    NARCIS (Netherlands)

    Giltay, E.J.; Kamphuis, M.H.; Kalmijn, S.; Zitman, F.G.; Kromhout, D.

    2006-01-01

    Background: Dispositional optimism, defined in terms of life engagement and generalized positive outcome expectancies for one¿s future, may be related to lower cardiovascular mortality. We aimed to determine whether dispositional optimism is a stable trait over time and whether it is independently

  20. Long-lasting effects of affective disorders and childhood trauma on dispositional optimism

    NARCIS (Netherlands)

    Broekhof, R.; Rius-Ottenheim, N.; Spinhoven, P.; van der Mast, R.C.; Penninx, B.W.; Zitman, F. G.; Giltay, E.J.

    2015-01-01

    Background Dispositional optimism, a personality trait characterized by generalized positive expectations towards the future, is thought to remain rather stable over time. It is however largely unknown to what extent affective disorders and its risk factors affect dispositional optimism. Methods We

  1. Lifestyle and dietary correlates of dispositional optimism in men: The Zutphen Elderly Study

    NARCIS (Netherlands)

    Giltay, E.J.; Geleijnse, J.M.; Zitman, F.G.; Buijsse, B.; Kromhout, D.

    2007-01-01

    Objective: Dispositional optimism has been associated with a lower risk of cardiovascular mortality, but the underlying mechanisms are still largely unknown. We therefore studied whether dispositional optimism was associated with healthy lifestyle and dietary habits. Methods: In 773 (87.1%) of 887

  2. 8 CFR 287.3 - Disposition of cases of aliens arrested without warrant.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Disposition of cases of aliens arrested without warrant. 287.3 Section 287.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.3 Disposition of cases of aliens arrested without warrant...

  3. The Human Factor: Student Reactions to the Integration of Personal Dispositions into a Counseling Program

    Science.gov (United States)

    Gibbons, Melinda M.; Cochran, Jeff L.; Spurgeon, Shawn; Diambra, Joel F.

    2013-01-01

    The authors explored student reactions to the integration of personal dispositions, or characteristic attitudes, into a counseling program. Results suggested participants liked focusing on personal dispositions and were able to identify areas of personal growth related to these characteristics. Integrating humanistic principles by using…

  4. 39 CFR 946.4 - Disposition of property of unknown owners.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Disposition of property of unknown owners. 946.4 Section 946.4 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PROCEDURE RELATING TO THE... § 946.4 Disposition of property of unknown owners. (a) Where no apparent owner of property subject to...

  5. 39 CFR 946.2 - Disposition of property of apparent owners.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Disposition of property of apparent owners. 946.2... § 946.2 Disposition of property of apparent owners. Where an apparent owner of property subject to this... owner's last known address, written notice describing the property and the procedure for filing a claim...

  6. Critical Thinking Disposition: The Effects of Infusion Approach in Engineering Drawing

    Science.gov (United States)

    Darby, Norazlinda Mohd; Rashid, Abdullah Mat

    2017-01-01

    Critical Thinking Disposition is known as an important factor that drives a student to use Higher Order Thinking Skills (HOTS) in order to solve engineering drawing problems. Infusing them while teaching the subject may enhance students' disposition and higher order thinking skills. However, no research has been done in critical thinking…

  7. 32 CFR 552.104 - Disposition of confiscated/seized weapons.

    Science.gov (United States)

    2010-07-01

    ... Disposition of confiscated/seized weapons. All weapons, ammunition, explosives or other devices defined in... Investigation (FBI) for investigation, retention as evidence, or other lawful disposition. When retention for investigation or evidence is no longer required by military police, USACIDC, or other law enforcement or...

  8. Construct Validity Examination of Critical Thinking Dispositions for Undergraduate Students in University Putra Malaysia

    Science.gov (United States)

    Ghadi, Ibrahim; Alwi, Nor Hayati; Bakar, Kamariah Abu; Talib, Othman

    2012-01-01

    This research aims to evaluate the psychology properties of the construct validity for the Critical Thinking Disposition (CTD) instrument. The CTD instrument consists of 39 Likert-type items measuring seven dispositions, namely analyticity, open-mind, truth-seeking, systematicity, self-confidence inquisitiveness and maturity. The study involves…

  9. 27 CFR 40.478 - Disposition of cigarette papers and tubes and schedule.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Disposition of cigarette... PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Claims by Manufacturers § 40.478 Disposition of cigarette papers and tubes and schedule. When so...

  10. Neural correlates of envy: Regional homogeneity of resting-state brain activity predicts dispositional envy.

    Science.gov (United States)

    Xiang, Yanhui; Kong, Feng; Wen, Xue; Wu, Qihan; Mo, Lei

    2016-11-15

    Envy differs from common negative emotions across cultures. Although previous studies have explored the neural basis of episodic envy via functional magnetic resonance imaging (fMRI), little is known about the neural processes associated with dispositional envy. In the present study, we used regional homogeneity (ReHo) as an index in resting-state fMRI (rs-fMRI) to identify brain regions involved in individual differences in dispositional envy, as measured by the Dispositional Envy Scale (DES). Results showed that ReHo in the inferior/middle frontal gyrus (IFG/MFG) and dorsomedial prefrontal cortex (DMPFC) positively predicted dispositional envy. Moreover, of all the personality traits measured by the Revised NEO Personality Inventory (NEO-PI-R), only neuroticism was significantly associated with dispositional envy. Furthermore, neuroticism mediated the underlying association between the ReHo of the IFG/MFG and dispositional envy. Hence, to the best of our knowledge, this study provides the first evidence that spontaneous brain activity in multiple regions related to self-evaluation, social perception, and social emotion contributes to dispositional envy. In addition, our findings reveal that neuroticism may play an important role in the cognitive processing of dispositional envy. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Examining brain structures associated with dispositional envy and the mediation role of emotional intelligence.

    Science.gov (United States)

    Xiang, Yanhui; Zhao, Sasa; Wang, Hanlin; Wu, Qihan; Kong, Feng; Mo, Lei

    2017-02-08

    Dispositional envy is distinguished by definition and neurally from episodic envy. While the neural correlates of episodic envy have been evaluated by specific tasks in previous studies, little is known about the structural neural basis of dispositional envy. In this study, we investigated the structural neural basis of dispositional envy underlying individual differences across two independent samples comprising a total of 100 young healthy adults. Firstly, 73 subjects' data (sample 1) was analyzed, and we assessed the association between regional gray matter volume (rGMV) and dispositional envy using voxel-based morphometry (VBM). Furthermore, we explored the role of emotional intelligence in the association between GMV and dispositional envy. VBM indicated that dispositional envy was positively correlated with GMV in the left dorsolateral prefrontal cortex (DLPFC) and superior temporal gyrus (STG). We also found that emotional intelligence partially mediated the association between DLPFC volume and dispositional envy. These results were replicated in another independent sample (Sample 2, n = 27). These results provide the first evidence that dispositional envy exhibits a structural neural correlation with the DLPFC and STG, and give a neutral explanation for why individuals with high emotional intelligence exhibit less envy.

  12. 27 CFR 70.183 - Administration and disposition of real estate acquired by the United States.

    Science.gov (United States)

    2010-04-01

    ... disposition of real estate acquired by the United States. 70.183 Section 70.183 Alcohol, Tobacco Products and... Property § 70.183 Administration and disposition of real estate acquired by the United States. (a) Persons charged with. The appropriate TTB officer shall have charge of all real estate which has been or shall be...

  13. Psychopathology and pain correlates of dispositional optimism in methadone-maintained patients

    Science.gov (United States)

    Beitel, Mark; Savant, Jonathan D.; Cutter, Christopher J.; Peters, Skye; Belisle, Nicole; Barry, Declan T.

    2012-01-01

    While higher levels of dispositional optimism are associated with decreased levels of psychopathology and pain, and higher levels of mental health functioning—important outcomes in opioid treatment programs—a paucity of studies has examined dispositional optimism among individuals with opioid use disorders. The aim of this study was to examine the clinical correlates (i.e., psychopathology, pain status) of dispositional optimism in opioid dependent patients enrolled in methadone maintenance treatment (MMT). A survey targeting demographics, pain, psychopathology, and dispositional optimism was administered to 150 MMT patients. In multivariable analyses, higher levels of dispositional optimism were significantly associated with lower levels of depression, screened personality disorder criteria, screened symptoms of PTSD, and pain-related emotional strain. In comparison to those without a history of chronic pain (i.e., non-cancer related physical pain lasting at least 3 months), MMT patients who reported either lifetime or current chronic pain exhibited significantly lower levels of dispositional optimism. The associations among higher levels of dispositional optimism, lower levels of psychopathology, and lower pain-related emotional strain suggest that research focusing on the efficacy of specific interventions to promote dispositional optimism in MMT patients is warranted. PMID:23786512

  14. Metaphor as a Methodological Tool: Identifying Teachers' Social Justice Dispositions across Diverse Secondary School Settings

    Science.gov (United States)

    Mills, Carmen; Molla, Tebeje; Gale, Trevor; Cross, Russell; Parker, Stephen; Smith, Catherine

    2017-01-01

    This article investigates the social justice dispositions of teachers and principals in secondary schools as inferred from their metaphoric expressions. Drawing on a Bourdieuian account of disposition, our focus is the use of metaphor as a methodological tool to identify and reveal these otherwise latent forces within our data. Our analysis shows…

  15. A Validation Study of the "School Leader Dispositions Inventory"[C

    Science.gov (United States)

    Melton, Teri Denlea; Tysinger, Dawn; Mallory, Barbara; Green, James

    2011-01-01

    Although university-based school administrator preparation programs are required by accreditation agencies to assess the dispositions of candidates, valid and reliable methods for doing so remain scarce. "The School Leaders Disposition Inventory"[C] (SDLI) is proposed as an instrument that has promise for identifying leadership…

  16. Preservice Teachers' Critical Thinking Dispositions and Web 2.0 Competencies

    Science.gov (United States)

    Sendag, Serkan; Erol, Osman; Sezgin, Sezan; Dulkadir, Nihal

    2015-01-01

    The aim of this study was to investigate the associations between preservice teachers' Web 2.0 competencies and their critical thinking disposition (CTD). The study employed an associational research design using California Critical Thinking Disposition-Inventory (CCTD-I) and a Web 2.0 competency questionnaire including items related to Web 2.0…

  17. Self-Perceived Dispositions that Predict Challenges during Student Teaching: A Data Mining Analysis

    Science.gov (United States)

    Masunaga, Hiromi; Lewis, Trini

    2011-01-01

    In light of the issue related to consensus about the definition of dispositions and the larger issue pertaining to the absence of a model to predict the growth of pre-service teachers in their knowledge, skills, and dispositions that Teacher Performance Expectations (TPEs) specify, the purpose of this study is two-fold. First, the authors aim at…

  18. California Critical Thinking Disposition Inventory: further factor analytic examination.

    Science.gov (United States)

    Walsh, Catherine M; Seldomridge, Lisa A; Badros, Karen K

    2007-02-01

    The stability of the factor structure of the California Critical Thinking Disposition Inventory was re-examined using a convenience sample of 800 undergraduate students from nursing (n=520 first bachelors' and n=185 second bachelors' students) and biology (n=95) enrolled in introductory courses in their majors at a 4-yr. mid-Atlantic public university. Ages ranged from 17 to 54 years (M = 23.0, SD = 5.9), with 92 men and 707 women (1 missing). 685 participants identified themselves as Euro-American, 65 as African American, 9 as Hispanic, 26 as Asian, and 11 as "Other" (4 missing). The inventory developed by Facione in 1994 is a 75-item, forced-choice, adjective checklist, yielding seven subscores and a total score assessing testees' disposition toward critical thinking. A principal components factor analysis did not replicate the original factor structure of seven factors but supported the stability of a four-factor structure which had emerged in previous work by Walsh and Hardy and by Kakai. When the 75 original items were reduced to 25, the explained variance for the inventory improved from 27% to 44.95%. Thus, further investigation and continued refinement is warranted.

  19. Neural correlates of dispositional mindfulness during affect labeling.

    Science.gov (United States)

    Creswell, J David; Way, Baldwin M; Eisenberger, Naomi I; Lieberman, Matthew D

    2007-01-01

    Mindfulness is a process whereby one is aware and receptive to present moment experiences. Although mindfulness-enhancing interventions reduce pathological mental and physical health symptoms across a wide variety of conditions and diseases, the mechanisms underlying these effects remain unknown. Converging evidence from the mindfulness and neuroscience literature suggests that labeling affect may be one mechanism for these effects. Participants (n = 27) indicated trait levels of mindfulness and then completed an affect labeling task while undergoing functional magnetic resonance imaging. The labeling task consisted of matching facial expressions to appropriate affect words (affect labeling) or to gender-appropriate names (gender labeling control task). After controlling for multiple individual difference measures, dispositional mindfulness was associated with greater widespread prefrontal cortical activation, and reduced bilateral amygdala activity during affect labeling, compared with the gender labeling control task. Further, strong negative associations were found between areas of prefrontal cortex and right amygdala responses in participants high in mindfulness but not in participants low in mindfulness. The present findings with a dispositional measure of mindfulness suggest one potential neurocognitive mechanism for understanding how mindfulness meditation interventions reduce negative affect and improve health outcomes, showing that mindfulness is associated with enhanced prefrontal cortical regulation of affect through labeling of negative affective stimuli.

  20. Thinking critically about critical thinking: ability, disposition or both?

    Science.gov (United States)

    Krupat, Edward; Sprague, Jared M; Wolpaw, Daniel; Haidet, Paul; Hatem, David; O'Brien, Bridget

    2011-06-01

    The objectives of this study were to determine the extent to which clinician-educators agree on definitions of critical thinking and to determine whether their descriptions of critical thinking in clinical practice are consistent with these definitions. Ninety-seven medical educators at five medical schools were surveyed. Respondents were asked to define critical thinking, to describe a clinical scenario in which critical thinking would be important, and to state the actions of a clinician in that situation who was thinking critically and those of another who was not. Qualitative content analysis was conducted to identify patterns and themes. The definitions mostly described critical thinking as a process or an ability; a minority of respondents described it as a personal disposition. In the scenarios, however, the majority of the actions manifesting an absence of critical thinking resulted from heuristic thinking and a lack of cognitive effort, consistent with a dispositional approach, rather than a lack of ability to analyse or synthesise. If we are to foster critical thinking among medical students, we must reconcile the way it is defined with the manner in which clinician-educators describe critical thinking--and its absence--in action. Such a reconciliation would include consideration of clinicians' sensitivity to complexity and their inclination to exert cognitive effort, in addition to their ability to master material and process information. © Blackwell Publishing Ltd 2011.

  1. Stereoselective disposition and glucuronidation of propranolol in humans.

    Science.gov (United States)

    Silber, B; Holford, N H; Riegelman, S

    1982-06-01

    Following oral dosing to steady state, the disposition of S(-)- and R(+)-propranolol and their corresponding glucuronide conjugates was studied in 4 healthy adults using doses from 40 to 320 mg/day of the racemate. Steady -state plasma concentrations of S(-)-propranolol and its corresponding glucuronide conjugate were greater than that for R(+)-propranolol and its corresponding conjugate. The average steady-state concentration of both enantiomers increased disproportionately to dose. There was a 52+/- 7 (mean +/- SD) % decrease in the intrinsic clearance (clint) of S(-)-propranolol and a 65 +/- 22% decrease in the Clint of R(+)-propranolol over the dosing range studied. The terminal elimination half-lives of S(-)-propranolol and its glucuronide conjugate were longer than for the R(+)-enantiomer at all doses. The formation of glucuzonide conjugates of S(-)- and R(+)-propranolol was best described by a saturable process in all subjects. Within individuals, the ratio of Vmax/Km for the glucuronide conjugate of S(-)-propranolol was from 2.1-to 4.9-fold greater than for the conjugate of the R(+)-enantiomer. These studies demonstrate for the first time, that propranolol undergoes stereoselective disposition in humans.

  2. Child and adolescent conduct disorder substantially shares genetic influences with three socioemotional dispositions.

    Science.gov (United States)

    Waldman, Irwin D; Tackett, Jennifer L; Van Hulle, Carol A; Applegate, Brooks; Pardini, Dustin; Frick, Paul J; Lahey, Benjamin B

    2011-02-01

    In a representative sample of twin children and adolescents, we tested the hypothesis that a substantial proportion of the genetic and environmental influences underlying conduct disorder (CD) are shared with three socioemotional dispositions: Prosociality, Negative Emotionality, and Daring. Caretaker ratings of each dispositional dimension were uniquely associated with a latent CD dimension that included both caretaker- and youth-reports of CD as indicators. Behavior genetic analyses indicated that moderate-to-high additive genetic and moderate nonshared environmental influences underlie all three dispositions and CD, with modest shared environmental influences on Prosociality. Forty percent of the additive genetic influences and all of the nonshared environmental influences on the latent CD dimension were shared in common with the three socioemotional dispositions. The finding that CD shares a substantial proportion of its genetic influences with three distinct socioemotional dispositions suggests new perspectives on the heterogeneous etiology of CD and new approaches to exploring its specific etiological mechanisms. (c) 2010 APA, all rights reserved.

  3. Critical thinking dispositions and learning styles of baccalaureate nursing students from China.

    Science.gov (United States)

    Zhang, Huan; Lambert, Vickie

    2008-09-01

    Although considerable information exists regarding the learning styles and critical thinking dispositions of nursing students from Western countries, limited comparable information exists within China. The purposes of this study were to assess the learning styles and critical thinking dispositions of Chinese baccalaureate nursing students and to identify the relationships among the learning styles, critical thinking dispositions, and demographics. The sample consisted of 100 Chinese baccalaureate nursing students enrolled at two universities. The data were obtained through a Demographic Data Questionnaire, the California Critical Thinking Disposition Inventory, and the Index of Learning Styles. The primary learning style dimensions were found to be reflective, sensing, visual, and global, while the critically thinking abilities was found to be weak. A number of positive and negative correlations were found among the demographics, learning styles, and critical thinking dispositions. These findings suggest further examination on how to increase nursing students' critical thinking skills based upon their preferred learning styles.

  4. 26 CFR 1.468A-6T - Disposition of an interest in a nuclear power plant (temporary).

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Disposition of an interest in a nuclear power... § 1.468A-6T Disposition of an interest in a nuclear power plant (temporary). (a) In general. This... disposition by a taxpayer (transferor) of all or a portion of its qualifying interest in a nuclear power plant...

  5. Irreversible processes kinetic theory

    CERN Document Server

    Brush, Stephen G

    2013-01-01

    Kinetic Theory, Volume 2: Irreversible Processes deals with the kinetic theory of gases and the irreversible processes they undergo. It includes the two papers by James Clerk Maxwell and Ludwig Boltzmann in which the basic equations for transport processes in gases are formulated, together with the first derivation of Boltzmann's ""H-theorem"" and a discussion of this theorem, along with the problem of irreversibility.Comprised of 10 chapters, this volume begins with an introduction to the fundamental nature of heat and of gases, along with Boltzmann's work on the kinetic theory of gases and s

  6. Chemical Kinetics Database

    Science.gov (United States)

    SRD 17 NIST Chemical Kinetics Database (Web, free access)   The NIST Chemical Kinetics Database includes essentially all reported kinetics results for thermal gas-phase chemical reactions. The database is designed to be searched for kinetics data based on the specific reactants involved, for reactions resulting in specified products, for all the reactions of a particular species, or for various combinations of these. In addition, the bibliography can be searched by author name or combination of names. The database contains in excess of 38,000 separate reaction records for over 11,700 distinct reactant pairs. These data have been abstracted from over 12,000 papers with literature coverage through early 2000.

  7. Thermal kinetic inductance detector

    Science.gov (United States)

    Cecil, Thomas; Gades, Lisa; Miceli, Antonio; Quaranta, Orlando

    2016-12-20

    A microcalorimeter for radiation detection that uses superconducting kinetic inductance resonators as the thermometers. The detector is frequency-multiplexed which enables detector systems with a large number of pixels.

  8. Geometry-controlled kinetics.

    Science.gov (United States)

    Bénichou, O; Chevalier, C; Klafter, J; Meyer, B; Voituriez, R

    2010-06-01

    It has long been appreciated that the transport properties of molecules can control reaction kinetics. This effect can be characterized by the time it takes a diffusing molecule to reach a target-the first-passage time (FPT). Determining the FPT distribution in realistic confined geometries has until now, however, seemed intractable. Here, we calculate this FPT distribution analytically and show that transport processes as varied as regular diffusion, anomalous diffusion, and diffusion in disordered media and fractals, fall into the same universality classes. Beyond the theoretical aspect, this result changes our views on standard reaction kinetics and we introduce the concept of 'geometry-controlled kinetics'. More precisely, we argue that geometry-and in particular the initial distance between reactants in 'compact' systems-can become a key parameter. These findings could help explain the crucial role that the spatial organization of genes has in transcription kinetics, and more generally the impact of geometry on diffusion-limited reactions.

  9. Evaluation of Used Fuel Disposition in Clay-Bearing Rock

    Energy Technology Data Exchange (ETDEWEB)

    Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Weck, Philippe F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hammond, Glenn Edward [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kuhlman, Kristopher L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Zheng, Liange [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rutqvist, Jonny [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kim, Kunhwi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Houseworth, James [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Caporuscio, Florie Andre [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cheshire, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Palaich, Sarah [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Norskog, Katherine E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavarin, Mavrik [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolery, Thomas J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jerden, James L. [Argonne National Lab. (ANL), Argonne, IL (United States); Copple, Jacqueline M. [Argonne National Lab. (ANL), Argonne, IL (United States); Cruse, Terry [Argonne National Lab. (ANL), Argonne, IL (United States); Ebert, William L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-09-04

    Deep geological disposal of nuclear waste in clay/shale/argillaceous rock formations has received much consideration given its desirable attributes such as isolation properties (low permeability), geochemically reduced conditions, slow diffusion, sorbtive mineralogy, and geologically widespread (Jové Colón et al., 2014). There is a wealth of gained scientific expertise on the behavior of clay/shale/ argillaceous rock given its focus in international nuclear waste repository programs that includes underground research laboratories (URLs) in Switzerland, France, Belgium, and Japan. Jové Colón et al. (2014) have described some of these investigative efforts in clay rock ranging from site characterization to research on the engineered barrier system (EBS). Evaluations of disposal options that include nuclear waste disposition in clay/shale/argillaceous rock have determined that this host media can accommodate a wide range of waste types. R&D work within the Used Fuel Disposition Campaign (UFDC) assessing thermal effects and fluid-mineral interactions for the disposition of heat-generating waste have so far demonstrated the feasibility for the EBS and clay host rock to withstand high thermal loads. This report represents the continuation of disposal R&D efforts on the advancement and refinement of coupled Thermal-Hydrological-Mechanical-Chemical (THMC), hydrothermal experiments on clay interactions, used fuel degradation (source term), and thermodynamic modeling and database development. The development and implementation of a clay/shale/argillite reference case described in Jové Colón et al. (2014) for FY15 will be documented in another report (Mariner et al. 2015) – only a brief description will be given here. This clay reference case implementation is the result of integration efforts between the GDSA PA and disposal in argillite work packages. The assessment of sacrificial zones in the EBS is being addressed through experimental work along with 1D reactive

  10. Fundamentals of enzyme kinetics.

    Science.gov (United States)

    Seibert, Eleanore; Tracy, Timothy S

    2014-01-01

    This chapter provides a general introduction to the kinetics of enzyme-catalyzed reactions, with a focus on drug-metabolizing enzymes. A prerequisite to understanding enzyme kinetics is having a clear grasp of the meanings of "enzyme" and "catalysis." Catalysts are reagents that can increase the rate of a chemical reaction without being consumed in the reaction. Enzymes are proteins that form a subset of catalysts. These concepts are further explored below.

  11. Electrochemical kinetics theoretical aspects

    CERN Document Server

    Vetter, Klaus J

    1967-01-01

    Electrochemical Kinetics: Theoretical Aspects focuses on the processes, methodologies, reactions, and transformations in electrochemical kinetics. The book first offers information on electrochemical thermodynamics and the theory of overvoltage. Topics include equilibrium potentials, concepts and definitions, electrical double layer and electrocapillarity, and charge-transfer, diffusion, and reaction overvoltage. Crystallization overvoltage, total overvoltage, and resistance polarization are also discussed. The text then examines the methods of determining electrochemical reaction mechanisms

  12. Long-lasting effects of affective disorders and childhood trauma on dispositional optimism.

    Science.gov (United States)

    Broekhof, Rosalie; Rius-Ottenheim, Nathaly; Spinhoven, Philip; van der Mast, Roos C; Penninx, Brenda W J H; Zitman, Frans G; Giltay, Erik J

    2015-04-01

    Dispositional optimism, a personality trait characterized by generalized positive expectations towards the future, is thought to remain rather stable over time. It is however largely unknown to what extent affective disorders and its risk factors affect dispositional optimism. We examined the association between (lifetime) affective disorders and childhood trauma with dispositional optimism in a sample of 2104 subjects (aged 18-65 years) from the Netherlands Study of Depression and Anxiety (NESDA). Dispositional optimism was measured with the Life Orientation Test Revised (LOT-R). Diagnoses of depressive and anxiety disorders were based on the Composite Interview diagnostic Instrument (CIDI).Childhood trauma was assessed using the Childhood Trauma Interview (CTI) and life-events with the List of Threatening Events Questionnaire (LTQ). The 2104 participants were on average 46.0 (SD 13.1) years old and 65.8% were female. Multivariate analyses showed that dispositional optimism was inversely associated with current affective disorders (depression: B=-1.089 and anxiety: B=-1.066, both poptimism, whilst positive life-events were associated with higher levels of optimism (B=0.235, p>0.001). The cross-sectional design hampers inferences about causality. Lower levels of dispositional optimism are associated with stage of affective disorders, even after remission, and a history of childhood emotional maltreatment. Identification of the risk factors contributes to understand fluctuations in dispositional optimism. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Dispositional Mindfulness, Shame, and Compulsive Sexual Behaviors among Men in Residential Treatment for Substance Use Disorders.

    Science.gov (United States)

    Brem, Meagan J; Shorey, Ryan C; Anderson, Scott; Stuart, Gregory L

    2017-12-01

    Approximately 31% of men in treatment for a substance use disorders (SUD) engage in compulsive sexual behavior (CSB). Shame, a well-documented consequence of CSB, increases the likelihood of relapse following treatment for SUDs. Despite the risk of relapse, prior research has not investigated factors that may attenuate the relation between CSB and shame. Dispositional mindfulness is one such factor known to mitigate shame. However, researchers have yet to examine dispositional mindfulness as a moderator of the relationship between CSB and shame among a sample of men in treatment for SUDs. In an effort to inform intervention efforts, the present study aimed to investigate the hypothesis that CSB would not relate to shame among men with high, as opposed to low, levels of dispositional mindfulness. The present study reviewed medical records of 184 men in residential treatment for SUDs who completed cross-sectional measures of shame, CSB, dispositional mindfulness, and substance use problems. Results demonstrated a significant interaction between CSB and dispositional mindfulness such that CSB positively related to shame at low, but not mean or high, levels of dispositional mindfulness. These results support and extend previous mindfulness and CSB treatment research. Findings suggested that intervention efforts for CSB may benefit from increasing dispositional mindfulness in an effort to reduce shame-related cognitions.

  14. Nursing students' critical thinking disposition according to academic level and satisfaction with nursing.

    Science.gov (United States)

    Kim, Dong Hee; Moon, Seongmi; Kim, Eun Jung; Kim, Young-Ju; Lee, Sunhee

    2014-01-01

    The development of critical thinking dispositions has become an important issue in nursing education in Korea. Nursing colleges in Korea have developed teaching strategies and curricula that focus on developing critical thinking dispositions. It is an imperative step that evaluates the changing pattern and development of students' critical thinking dispositions. This study identified critical thinking dispositions of Korean nursing students according to academic level and satisfaction with nursing. A cross-sectional questionnaire survey was conducted among 1074 students in four colleges who completed the self-reported Critical Thinking Disposition Scale. Descriptive and univariate general linear model analyses were performed. The critical thinking disposition score increased according to academic level until junior year, after which it decreased in the senior year. Nursing students who were satisfied with nursing reported higher levels of critical thinking than those who were not satisfied or who responded neutrally. The critical thinking scores of nursing students not satisfied with nursing dropped greatly in the senior year. These results suggest the importance of targeting the development of curriculum and teaching methods for seniors and students who have a lower level of satisfaction with nursing to increase their critical thinking dispositions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. A Capital Sin: Dispositional Envy and its Relations to Wellbeing

    Directory of Open Access Journals (Sweden)

    Taciano L. Milfont

    2009-01-01

    Full Text Available Envy is a pancultural emotion felt by most individuals during their lifetime. The Dispositional Envy Scale (DES is a 8-item self-reported measure developed to assess people´s tendencies to feel envy. This study first examines the reliability and validity of the DES in measuring envy in a Brazilian sample, and then the relationship between envy and wellbeing. The DES had acceptable reliability (internal consistency and homogeneity as well as factorial and criterion-related validity. As expected, envy was negatively related to wellbeing measures (life satisfaction, vitality, and happiness, indicating that an envy-prone person is more likely to have low feelings of aliveness and energy, and to express unhappiness with their lives. The findings support the psychometric properties of the Brazilian-Portuguese version of the DES, and also highlight the potential impact of envy on people¿s wellbeing.

  16. [Dispositional optimism, pessimism and realism in technological potential entrepreneurs].

    Science.gov (United States)

    López Puga, Jorge; García García, Juan

    2011-11-01

    Optimism has been classically considered a key trait in entrepreneurs' personality but it has been studied from a psychological point of view only in recent years. The main aim of this research is to study the relationship between dispositional optimism, pessimism and realism as a function of the tendency to create technology-based businesses. A sample of undergraduate students (n= 205) filled in an electronic questionnaire containing the Life Orientation Test-Revised after they were classified as potential technological entrepreneurs, potential general entrepreneurs and non-potential entrepreneurs. Our results show that technology-based entrepreneurs are more optimistic than non-potential entrepreneurs, whereas there were no statistical differences in pessimism and realism. The results are interpreted theoretically to define the potential entrepreneur and, from an applied perspective, to design training programmes to support future technological entrepreneurs.

  17. Adaptation and validation of the dispositional hope scale for adolescents

    Directory of Open Access Journals (Sweden)

    Juliana Cerentini Pacico

    2013-01-01

    Full Text Available This paper describes the psychometric features and the validation process of the Adult Dispositional Hope Scale (ADHS for adolescents in the south of Brazil. This scale measures the Hope construct in terms of pathways and agency. The ADHS was translated to Portuguese and underwent a reverse translation. A sample of 450 students, from 14 to 18 years old (M=16.8 years, SD=3.4, 56% female, answered the ADHS, the Hope Index, the LOT-R and the Rosenberg's Self-Esteem Scale. A factorial analysis with varimax rotation showed that the scale is unidimensional and that its internal consistency was adequate (Cronbach's alpha = .80. No significant gender differences were found. Correlations of ADHS with the other constructs presented evidence of convergent validity in the present study.

  18. Cognitive and emotional predictors of episodic and dispositional forgiveness

    Directory of Open Access Journals (Sweden)

    Mróz Justyna

    2017-06-01

    Full Text Available The study examined the importance of cognitive (positive orientation, basic hope and emotional (positive and negative affectivity, emotional control variables for state and trait forgiveness. One hundred and thirty nine participants completed six inventories in Polish version: HFS (Thompson et al., 2005, TRIM (McCullough et al., 1998, P-Scale (Caprara et al., 2012, BHI-12 (Trzebiński & Zięba, 2003a, SUPIN (Polish version of PANAS; Watson, Clark, & Tellegen, 1988, CECS (Watson & Greer, 1983. Results showed that dispositional forgiveness (general and positive was associated with cognitive and emotional predictors, whereas episodic forgiveness primarily with certain emotional variables. In addition, the results indicated that emotional predictors merely participate in the process of reducing unforgiveness, whereas cognitive and emotional variables were shown to be necessary for full forgiveness.

  19. Reactor-Based Plutonium Disposition: Opportunities, Options, and Issues

    Energy Technology Data Exchange (ETDEWEB)

    Greene, S.R.

    1999-07-17

    The end of the Cold War has created a legacy of surplus fissile materials (plutonium and highly enriched uranium) in the United States (U.S.) and the former Soviet Union. These materials pose a danger to national and international security. During the past few years, the U.S. and Russia have engaged in an ongoing dialog concerning the safe storage and disposition of surplus fissile material stockpiles. In January 1997, the Department of Energy (DOE) announced the U. S. would pursue a dual track approach to rendering approximately 50 metric tons of plutonium inaccessible for use in nuclear weapons. One track involves immobilizing the plutonium by combining it with high-level radioactive waste in glass or ceramic ''logs''. The other method, referred to as reactor-based disposition, converts plutonium into mixed oxide (MOX) fuel for nuclear reactors. The U.S. and Russia are moving ahead rapidly to develop and demonstrate the technology required to implement the MOX option in their respective countries. U.S. MOX fuel research and development activities were started in the 1950s, with irradiation of MOX fuel rods in commercial light water reactors (LWR) from the 1960s--1980s. In all, a few thousand MOX fuel rods were successfully irradiated. Though much of this work was performed with weapons-grade or ''near'' weapons-grade plutonium--and favorable fuel performance was observed--the applicability of this data for licensing and use of weapons-grade MOX fuel manufactured with modern fuel fabrication processes is somewhat limited. The U.S. and Russia are currently engaged in an intensive research, development, and demonstration program to support implementation of the MOX option in our two countries. This paper focuses on work performed in the U.S. and provides a brief summary of joint U.S./Russian work currently underway.

  20. Disposition of eslicarbazepine acetate in the mouse after oral administration.

    Science.gov (United States)

    Alves, Gilberto; Figueiredo, Isabel; Castel-Branco, Margarida; Lourenço, Nulita; Falcão, Amílcar; Caramona, Margarida; Soares-da-Silva, Patrício

    2008-10-01

    Eslicarbazepine acetate is a promising antiepileptic drug structurally related to carbamazepine and oxcarbazepine, which is in the final phase of clinical development. The metabolism of eslicarbazepine acetate is clearly species dependent and, in this case, among small laboratory animals, the mouse seems to be the most relevant species to humans. Hence, the aim of this study was to investigate the plasma, brain and liver disposition of eslicarbazepine acetate in mice to better understand its disposition in humans. Adult male CD-1 mice were treated orally with a single dose of eslicarbazepine acetate 350 mg/kg. Blood samples, brain and liver tissues were taken at 0.25, 0.5, 0.75, 1, 2, 4, 6, 10, 16 and 24 h post-dose. Plasma and tissue levels of eslicarbazepine acetate and its metabolites (S-licarbazepine, R-licarbazepine and oxcarbazepine) were assessed by using high-performance liquid chromatography-ultraviolet detection. Both eslicarbazepine acetate and R-licarbazepine concentrations were below the limit of quantification of the assay in all matrices. Eslicarbazepine acetate was rapidly and extensively metabolized to S-licarbazepine (major metabolite), which was oxidized to oxcarbazepine to a small extent. The brain/plasma ratios suggest that the brain exposure to S-licarbazepine and oxcarbazepine was approximately 30% of their total systemic exposure. However, S-licarbazepine crossed the blood-brain barrier (BBB) less efficiently than oxcarbazepine. On the other hand, the liver/plasma ratios support the notion that S-licarbazepine undergoes hepatic accumulation, whereas oxcarbazepine appears to leave this compartment twice as fast as S-licarbazepine. Thus, the diffusion through the BBB is favourable to oxcarbazepine and the liver acts like a deposit of the pharmacologically active metabolite of eslicarbazepine acetate (S-licarbazepine).

  1. R&D plan for immobilization technologies: fissile materials disposition program. Revision 1.0

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, H.F.; Armantrout, G.A.

    1996-09-01

    In the aftermath of the Cold War, the US and Russia have agreed to large reductions in nuclear weapons. To aid in the selection of long- term fissile material management options, the Department of Energy`s Fissile Materials Disposition Program (FMDP) is conducting studies of options for the storage and disposition of surplus plutonium (Pu). One set of alternatives for disposition involve immobilization. The immobilization alternatives provide for fixing surplus fissile materials in a host matrix in order to create a solid disposal form that is nuclear criticality-safe, proliferation-resistant and environmentally acceptable for long-term storage or disposal.

  2. Goal orientation, motivational climate, and dispositional flow of high school students engaged in extracurricular physical activity.

    Science.gov (United States)

    Cervelló, Eduardo M; Moreno, Juan A; Villodre, Nestor Alonso; Iglesias, Damián

    2006-02-01

    The purpose of this study was to examine the role of goal orientation, motivational climate, and dispositional flow in physical education lessons on extracurricular involvement in physical activity. Questionnaires were administered to 1,103 (792 athletes; 311 nonathletes) secondary school students (M age = 14.3 yr., SD = 0.7). Analysis showed significant mean differences between groups on goal orientation and dispositional flow in physical education lessons, but none for perception of motivational climate. These findings suggest that dispositional variables are related to extracurricular involvement in physical activity.

  3. Multiple alternative substrate kinetics.

    Science.gov (United States)

    Anderson, Vernon E

    2015-11-01

    The specificity of enzymes for their respective substrates has been a focal point of enzyme kinetics since the initial characterization of metabolic chemistry. Various processes to quantify an enzyme's specificity using kinetics have been utilized over the decades. Fersht's definition of the ratio kcat/Km for two different substrates as the "specificity constant" (ref [7]), based on the premise that the important specificity existed when the substrates were competing in the same reaction, has become a consensus standard for enzymes obeying Michaelis-Menten kinetics. The expansion of the theory for the determination of the relative specificity constants for a very large number of competing substrates, e.g. those present in a combinatorial library, in a single reaction mixture has been developed in this contribution. The ratio of kcat/Km for isotopologs has also become a standard in mechanistic enzymology where kinetic isotope effects have been measured by the development of internal competition experiments with extreme precision. This contribution extends the theory of kinetic isotope effects to internal competition between three isotopologs present at non-tracer concentrations in the same reaction mix. This article is part of a special issue titled: Enzyme Transition States from Theory and Experiment. Published by Elsevier B.V.

  4. Erbium hydride decomposition kinetics.

    Energy Technology Data Exchange (ETDEWEB)

    Ferrizz, Robert Matthew

    2006-11-01

    Thermal desorption spectroscopy (TDS) is used to study the decomposition kinetics of erbium hydride thin films. The TDS results presented in this report are analyzed quantitatively using Redhead's method to yield kinetic parameters (E{sub A} {approx} 54.2 kcal/mol), which are then utilized to predict hydrogen outgassing in vacuum for a variety of thermal treatments. Interestingly, it was found that the activation energy for desorption can vary by more than 7 kcal/mol (0.30 eV) for seemingly similar samples. In addition, small amounts of less-stable hydrogen were observed for all erbium dihydride films. A detailed explanation of several approaches for analyzing thermal desorption spectra to obtain kinetic information is included as an appendix.

  5. Impact of learning adaptability and time management disposition on study engagement among Chinese baccalaureate nursing students.

    Science.gov (United States)

    Liu, Jing-Ying; Liu, Yan-Hui; Yang, Ji-Peng

    2014-01-01

    The aim of this study was to explore the relationships among study engagement, learning adaptability, and time management disposition in a sample of Chinese baccalaureate nursing students. A convenient sample of 467 baccalaureate nursing students was surveyed in two universities in Tianjin, China. Students completed a questionnaire that included their demographic information, Chinese Utrecht Work Engagement Scale-Student Questionnaire, Learning Adaptability Scale, and Adolescence Time Management Disposition Scale. One-way analysis of variance tests were used to assess the relationship between certain characteristics of baccalaureate nursing students. Pearson correlation was performed to test the correlation among study engagement, learning adaptability, and time management disposition. Hierarchical linear regression analyses were performed to explore the mediating role of time management disposition. The results revealed that study engagement (F = 7.20, P students but also focus on development, investment in adaptability, and time management. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Improving critical thinking : Effects of dispositions and instructions oneconomics students' reasoning skills

    NARCIS (Netherlands)

    Heijltjes, Anita; van Gog, Tamara; Leppink, Jimmie; Paas, Fred

    2014-01-01

    This experiment investigated the impact of critical thinking dispositions and instructions on economics students' performance on reasoning skills. Participants (. N=. 183) were exposed to one of four conditions: critical thinking instruction, critical thinking instruction with self-explanation

  7. Dispositional mindfulness, spirituality, and substance use in predicting depressive symptoms in a treatment-seeking sample.

    Science.gov (United States)

    Shorey, Ryan C; Gawrysiak, Michael J; Anderson, Scott; Stuart, Gregory L

    2015-04-01

    It is imperative that research identifies factors related to depression among individuals in substance use treatment, as depression is associated with substance use relapse. Dispositional mindfulness and spirituality may bear an important role in the relationship between depression and substance use. Using preexisting patient medical records (N = 105), the current study investigated dispositional mindfulness and spirituality in relation to depressive symptom clusters (affective, cognitive, and physiological) among men in residential substance use treatment. The mean age of the sample was 41.03 (standard deviation = 10.75). Findings demonstrated that dispositional mindfulness and spirituality were negatively associated with depressive symptoms. After controlling for age, alcohol use, and drug use, dispositional mindfulness remained negatively associated with all of the depression clusters. Spirituality only remained associated with the cognitive depression cluster. Mindfulness-based interventions may hold promise as an effective intervention for reducing substance use and concurrent depressive symptoms. © 2014 Wiley Periodicals, Inc.

  8. 105-N basin sediment disposition phase-two sampling and analysis plan

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R. C.

    1997-03-14

    The sampling and analysis plan for Phase 2 of the 105-N Basin sediment disposition task defines the sampling and analytical activities that will be performed to support characterization of the sediment and selection of an appropriate sediment disposal option.

  9. 7 CFR 301.51-8 - Attachment and disposition of certificates and limited permits.

    Science.gov (United States)

    2010-01-01

    ...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Asian Longhorned Beetle § 301.51-8 Attachment and disposition of certificates and limited permits. (a) A regulated...

  10. Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion

    NARCIS (Netherlands)

    Modinos, Gemma; Ormel, Johan; Aleman, Andre

    2010-01-01

    The regulation of negative emotion through reappraisal has been shown to induce increased prefrontal activity and decreased amygdala activity. Individual differences in dispositional mindfulness reflect differences in typical recognition, detachment and regulation of current experience, thought to

  11. 7 CFR 301.55-8 - Attachment and disposition of certificates and limited permits.

    Science.gov (United States)

    2010-01-01

    ...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES South American Cactus Moth § 301.55-8 Attachment and disposition of certificates and limited permits. (a) A...

  12. Dispositions to school education and self concept in Slovenian and British high-school students

    Directory of Open Access Journals (Sweden)

    Darja Kobal

    2001-09-01

    Full Text Available The article highlights the relationship between dispositions to school education and self-concept. What is meant by the expression "dispositions of school education" are phenomena like attitudes to school, achievement motivation, believes about personal control over learning, external constrains to learning etc. The definition of self-concept and its brief contemporary understanding is mentioned. The aim of the study is to find out the expression of certain areas of self-concept and dispositions to school education. A group of Slovenian and a group of British high school students participated in the study. The results of ANOVA and discriminant analysis showed significant differences as related to nationality. For example, British participants exceeded Slovenians in many areas of self-concept. They also expressed some significant differences in their dispositions to school. The results are interpreted in the light of personality and national differences.

  13. 14 CFR 43.9 - Content, form, and disposition of maintenance, preventive maintenance, rebuilding, and alteration...

    Science.gov (United States)

    2010-01-01

    ... maintenance, preventive maintenance, rebuilding, and alteration records (except inspections performed in..., PREVENTIVE MAINTENANCE, REBUILDING, AND ALTERATION § 43.9 Content, form, and disposition of maintenance, preventive maintenance, rebuilding, and alteration records (except inspections performed in accordance with...

  14. Sample results from the interim salt disposition program macrobatch 9 tank 21H qualification samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-11-01

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of qualification of Macrobatch (Salt Batch) 9 for the Interim Salt Disposition Program (ISDP). This document reports characterization data on the samples of Tank 21H.

  15. The effect of surgery (Ovariohysterectomy) on the plasma disposition of meloxicam following intravenous administration in dogs

    National Research Council Canada - National Science Library

    Karademir, Umit; Aksit, Dilek; Kum, Cavit; Erdogan, Hasan; Ucar, Eyup Hakan; Peker, Cevdet; Gokbulut, Cengiz

    2016-01-01

    .... This study was designed to investigate the effect of surgery on the plasma disposition of MLX in dogs undergoing ovariohysterectomy following a single intravenous injection at a dose of 0.2 mg/kg bodyweight...

  16. Does Body Mass Index Influence Behavioral Regulations, Dispositional Flow and Social Physique Anxiety in Exercise Setting?

    Directory of Open Access Journals (Sweden)

    Gözde Ersöz, Ersin Altiparmak, F. Hülya Aşçı

    2016-06-01

    Full Text Available The purpose of this study was to examine differences in behavioral regulations, dispositional flow, social physique anxiety of exercisers in terms of body mass index (BMI. 782 university students participated in this study. Dispositional Flow State Scale-2, Behavioral Regulations in Exercise Questionnaire-2, Social Physique Anxiety Scale and Physical Activity Stages of Change Questionnaire were administered to participants. After controlling for gender, analysis indicated significant differences in behavioral regulations, dispositional flow and social physique anxiety of exercise participants with regards to BMI. In summary, the findings demonstrate that normal weighted participants exercise for internal reasons while underweighted participants are amotivated for exercise participation. Additionally, participants who are underweight had higher dispositional flow and lower social physique anxiety scores than other BMI classification.

  17. Tebuconazole photocatalytic degradation kinetics

    OpenAIRE

    Prestes, Thiago de Hermann; Gibbon, Danielle de Oliveira; Lansarin, Marla Azário; Moro, Celso Camilo

    2010-01-01

    The tebuconazole photocatalytic degradation kinetics was studied in a batch reactor using TiO2 (P25-Degussa) as catalyst and a high pressure mercury lamp. The photolysis, adsorption and irradiation effects in the reaction rate were evaluated. Afterward, the suspension catalyst concentration and initial pH to the maximum reaction rate was determined. It was observed that the reaction rate can be approached by a pseudo-first order, with a maximum kinetics constant at 260 mg L-1catalyst concentr...

  18. Chemical Disposition of Plutonium in Hanford Site Tank Wastes

    Energy Technology Data Exchange (ETDEWEB)

    Delegard, Calvin H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jones, Susan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-05-07

    This report examines the chemical disposition of plutonium (Pu) in Hanford Site tank wastes, by itself and in its observed and potential interactions with the neutron absorbers aluminum (Al), cadmium (Cd), chromium (Cr), iron (Fe), manganese (Mn), nickel (Ni), and sodium (Na). Consideration also is given to the interactions of plutonium with uranium (U). No consideration of the disposition of uranium itself as an element with fissile isotopes is considered except tangentially with respect to its interaction as an absorber for plutonium. The report begins with a brief review of Hanford Site plutonium processes, examining the various means used to recover plutonium from irradiated fuel and from scrap, and also examines the intermediate processing of plutonium to prepare useful chemical forms. The paper provides an overview of Hanford tank defined-waste–type compositions and some calculations of the ratios of plutonium to absorber elements in these waste types and in individual waste analyses. These assessments are based on Hanford tank waste inventory data derived from separately published, expert assessments of tank disposal records, process flowsheets, and chemical/radiochemical analyses. This work also investigates the distribution and expected speciation of plutonium in tank waste solution and solid phases. For the solid phases, both pure plutonium compounds and plutonium interactions with absorber elements are considered. These assessments of plutonium chemistry are based largely on analyses of idealized or simulated tank waste or strongly alkaline systems. The very limited information available on plutonium behavior, disposition, and speciation in genuine tank waste also is discussed. The assessments show that plutonium coprecipitates strongly with chromium, iron, manganese and uranium absorbers. Plutonium’s chemical interactions with aluminum, nickel, and sodium are minimal to non-existent. Credit for neutronic interaction of plutonium with these absorbers

  19. Does Body Mass Index Influence Behavioral Regulations, Dispositional Flow and Social Physique Anxiety in Exercise Setting?

    OpenAIRE

    Gözde Ersöz, Ersin Altiparmak, F. Hülya Aşçı

    2016-01-01

    The purpose of this study was to examine differences in behavioral regulations, dispositional flow, social physique anxiety of exercisers in terms of body mass index (BMI). 782 university students participated in this study. Dispositional Flow State Scale-2, Behavioral Regulations in Exercise Questionnaire-2, Social Physique Anxiety Scale and Physical Activity Stages of Change Questionnaire were administered to participants. After controlling for gender, analysis indicated significant differe...

  20. Critical Thinking Dispositions of Nursing Students in Asian and Non-Asian Countries: A Literature Review

    OpenAIRE

    Salsali, Mahvash; Tajvidi, Mansooreh; Ghiyasvandian, Shahrzad

    2013-01-01

    Critical thinking disposition represents an inclination of a person to use possessed skills in relation to critical thinking. The trend of critical thinking has been described as inner motivation to solve problems and make decisions by thinking. In nursing as a practical profession, the concept of critical thinking dispositions is important component in helping to manage complex health situations and to deal with patient issues effectively. Willingness to think critically is a prerequisite fo...

  1. Mathematical disposition of junior high school students viewed from learning styles

    Science.gov (United States)

    Putra, Arief Karunia; Budiyono, Slamet, Isnandar

    2017-08-01

    The relevance of this study is the growth of character values for students in Indonesia. Mathematics is a subject that builds the character values for students. It can be seen from the students' confidence in answering mathematics problems, their persistent and resilience in mathematics task. In addition, students have a curiosity in mathematics and appreciate the usefulness of mathematics. In mathematics, it is called a mathematical disposition. One of the factors that can affect students' mathematical disposition is learning style. Each student has a dominant learning style. Three of the most popular ones are visual, auditory, and kinesthetic. The most important uses of learning styles is that it makes it easy for teachers to incorporate them into their teaching. The purpose of this study was to determine which one that gives better mathematical dispositions among students with learning styles of visual, auditory, or kinesthetic. The subjects were 150 students in Sleman regency. Data obtained through questionnaires. Based on data analysis that has been done with benchmark assessment method, it can be concluded that students with visual learning style has a mathematical disposition better than students with auditory and kinesthetic learning styles, while students with kinesthetic learning style has a mathematical disposition better than students with auditory learning style. These results can be used as a reference for students with individual learning styles to improve the mathematical positive disposition in the learning process of mathematics.

  2. Burning With Envy? Dispositional and Situational Influences on Envy in Grandiose and Vulnerable Narcissism.

    Science.gov (United States)

    Neufeld, Darren C; Johnson, Edward A

    2016-10-01

    Research on narcissism and envy suggests a variable relationship that may reflect differences between how vulnerable and grandiose narcissism relate to precursors of envy. Accordingly, we proposed a model in which dispositional envy and relative deprivation differentially mediate envy's association with narcissistic vulnerability, grandiosity, and entitlement. To test the model, 330 young adults completed dispositional measures of narcissism, entitlement, and envy; one week later, participants reported on deprivation and envy feelings toward a peer who outperformed others on an intelligence test for a cash prize (Study 1) or earned higher monetary payouts in a betting game (Study 2). In both studies, structural equation modeling broadly supported the proposed model. Vulnerable narcissism robustly predicted episodic envy via dispositional envy. Entitlement-a narcissistic facet common to grandiosity and vulnerability-was a significant indirect predictor via relative deprivation. Study 2 also found that (a) the grandiose leadership/authority facet indirectly curbed envy feelings via dispositional envy, and (b) episodic envy contributed to schadenfreude feelings, which promoted efforts to sabotage a successful rival. Whereas vulnerable narcissists appear dispositionally envy-prone, grandiose narcissists may be dispositionally protected. Both, however, are susceptible to envy through entitlement when relative deprivation is encountered. © 2015 Wiley Periodicals, Inc.

  3. Dispositional pandemic worry and the health belief model: promoting vaccination during pandemic events.

    Science.gov (United States)

    Scherr, Courtney L; Jensen, Jakob D; Christy, Katheryn

    2017-12-01

    Promoting vaccination during pandemics is paramount to public health, yet few studies examined theoretical motivations for vaccination during pandemics. Thus, the relationships between dispositional pandemic worry, constructs of the health belief model (HBM) and vaccination during the H1N1 pandemic were studied. Participants (N = 1377) completed surveys assessing dispositional pandemic worry, HBM variables and H1N1 vaccination. Principle axis factor analysis and point biserial correlations were conducted. Differences in worry and vaccination were assessed via independent samples t-tests. Relationships between vaccination, demographics and worry were investigated using hierarchical linear regression. PROCESS analysis was conducted to explicate the relationship between worry and vaccination intention. A two-factor structure of dispositional pandemic worry-worry frequency and worry severity-was confirmed. Dispositional worry was higher among those who intended to and received H1N1 vaccine. Worry frequency and worry severity were positively related to vaccination. Threat, benefits and barriers mediated the impact of worry severity and threat and barriers mediated the impact of worry frequency on vaccination intentions. Messages increasing dispositional worry and benefits while decreasing barriers may boost vaccination behavior during a pandemic event. Future study of relationships between dispositional worry and HBM variables is warranted.

  4. Kinetic energy budget details

    Indian Academy of Sciences (India)

    Abstract. This paper presents the detailed turbulent kinetic energy budget and higher order statistics of flow behind a surface-mounted rib with and without superimposed acoustic excitation. Pattern recognition technique is used to determine the large-scale structure magnitude. It is observed that most of the turbulence ...

  5. Modeling chemical kinetics graphically

    NARCIS (Netherlands)

    Heck, A.

    2012-01-01

    In literature on chemistry education it has often been suggested that students, at high school level and beyond, can benefit in their studies of chemical kinetics from computer supported activities. Use of system dynamics modeling software is one of the suggested quantitative approaches that could

  6. SHORT COMMUNICATION KINETIC SPECTROPHOTOMETRIC ...

    African Journals Online (AJOL)

    Preferred Customer

    ABSTRACT. ABSTRACT. A novel catalytic kinetic spectrophotometric method for the determination of iron is developed based on the catalytic effect of Fe(III) on the oxidation reaction of p-acetylarsenazo(ASApA) by potassium periodate. Maximum absorbance of the Fe(III)-ASApA-KIO4 system in 8.0 × 10-3 M sulfuric acid ...

  7. CATALYTIC KINETIC SPECTROPHOTOMETRIC DETERMINATION ...

    African Journals Online (AJOL)

    Based on the property that in 0.12 M sulfuric acid medium titanium(IV) catalyzes the discoloring reaction of DBS-arsenazo oxidized by potassium bromate, a new catalytic kinetic spectrophotometric method for the determination of trace titanium (IV) was developed. The linear range of the determination of titanium is

  8. CATALYTIC KINETIC SPECTROPHOTOMETRIC DETERMINATION ...

    African Journals Online (AJOL)

    Preferred Customer

    Research Center for Nanotechnology, Changchun University of Science and Technology,. Changchun 130022 ... Although catalytic kinetic spectrophotometry has been used in the determination of copper, the selectivity ... In this paper CPApA was used as the chromogenic agent, H2O2 as the oxidant, Cu(II) as the catalyst.

  9. Resting Brain Activity Related to Dispositional Mindfulness: a PET Study.

    Science.gov (United States)

    Gartenschläger, Martin; Schreckenberger, Mathias; Buchholz, Hans-Georg; Reiner, Iris; Beutel, Manfred E; Adler, Julia; Michal, Matthias

    2017-01-01

    Mindfulness denotes a state of consciousness characterized by receptive attention to and awareness of present events and experiences. As a personality trait, it constitutes the ability to become aware of mental activities such as sensations, images, feelings, and thoughts, and to disengage from judgment, conditioned emotions, and their cognitive processing or automatic inhibition. Default brain activity reflects the stream of consciousness and sense of self at rest. Analysis of brain activity at rest in persons with mindfulness propensity may help to elucidate the neurophysiological basis of this important mental trait. The sample consisted of 32 persons-23 with mental disorders and 9 healthy controls. Dispositional mindfulness (DM) was operationalized by Mindful Attention Awareness Scale (MAAS). Brain activity at rest with eyes closed was assessed by fluorodeoxyglucose positron emission tomography (F-18-FDG PET). After adjustment for depression, anxiety, age and years of education, resting glucose metabolism in superior parietal lobule and left precuneus/Brodmann area (BA) 7 was positively associated with DM. Activity of the left inferior frontal orbital gyrus (BA 47) and bilateral anterior thalamus were inversely associated with DM. DM appears to be associated with increased metabolic activity in some core area of the default mode network (DMN) and areas connected to the DMN, such as BA 7, hosting sense of self functions. Hypometabolism on the other hand was found in some nodes connected to the DMN, such as left inferior frontal orbital gyrus and bilateral thalamus, commonly related to functions of memory retrieval, decision making, or outward attention.

  10. Diagnostic approach to constipation impacts pediatric emergency department disposition.

    Science.gov (United States)

    Chumpitazi, Corrie E; Rees, Chris A; Camp, Elizabeth A; Henkel, Erin B; Valdez, Karina L; Chumpitazi, Bruno P

    2017-10-01

    Constipation is a common cause of abdominal pain in children presenting to the emergency department (ED). The objectives of this study were to determine the diagnostic evaluation undertaken for constipation and to assess the association of the evaluation with final ED disposition. A retrospective chart review of children presenting to the pediatric ED of a quaternary care children's hospital with abdominal pain that received a soap suds enema therapy. A total of 512 children were included, 270 (52.7%) were female, and the median age was 8.0 (IQR: 4.0-11.0). One hundred and thirty eight patients (27%) had a digital rectal exam (DRE), 120 (22.8%) had bloodwork performed, 218 (43%) had urinalysis obtained, 397 (77.5%) had abdominal radiographs, 120 (23.4%) had abdominal ultrasounds, and 18 (3.5%) had computed tomography scans. Children who had a DRE had a younger median age (6.0, IQR: 3.0-9.25 vs. 8.0, IQR: 4.0-12.0; pchildren diagnosed with fecal impaction in the ED varied. Abdominal imaging may be avoided if children receive a DRE. When children presenting to the ED with abdominal pain had an abdominal radiograph, they were more likely to be admitted. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. International collaboration on used fuel disposition crystalline rocks

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yifeng [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gardner, Payton [Univ. of Montana, Missoula, MT (United States); Kim, Geon-Young [Korean Atomic Energy Research Inst. Daejeon (Korea); Ji, Sung-Hoon [Korean Atomic Energy Research Inst., Daejeon (Korea)

    2016-08-01

    Active participation in international R&D is crucial for achieving the UFD long-term goals of conducting “experiments to fill data needs and confirm advanced modeling approaches” (by 2015) and of having a “robust modeling and experimental basis for evaluation of multiple disposal system options” (by 2020). DOE’s Office of Nuclear Energy (NE) and its Office of Used Fuel Disposition Research and Development (UFD) have developed a strategic plan to advance cooperation with international partners. The international collaboration on the evaluation of crystalline disposal media at Sandia National Laboratories (SNL) in FY16 focused on the following four activities: (1) thermal-hydrologic-mechanical-chemical modeling single fracture evolution; (2) simulations of flow and transport in Bedrichov Tunnel, Czech Republic, (3) completion of streaming potential testing at Korean Atomic Energy Research Institute (KAERI), and (4) technical data exchange with KAERI on thermal-hydrologic-mechanical (THM) properties and specifications of bentonite buffer materials. The first two activities are part of the Development of Coupled Models and their Validation against Experiments (DECOVALEX-2015) project.

  12. Dispositional mindfulness and subjective time in healthy individuals

    Directory of Open Access Journals (Sweden)

    Luisa eWeiner

    2016-05-01

    Full Text Available How a human observer perceives duration depends on the amount of events taking place during the timed interval, but also on psychological dimensions, such as emotional-wellbeing, mindfulness, impulsivity, and rumination. Here we aimed at exploring these influences on duration estimation and passage of time judgments. 117 healthy individuals filled out mindfulness (FFMQ, impulsivity (BIS-11, rumination (RRS, and depression (BDI-sf questionnaires. Participants also conducted verbal estimation and production tasks in the multiple seconds range. During these timing tasks, subjects were asked to read digits aloud that were presented on a computer screen. Each condition of the timing tasks differed in terms of the interval between the presentation of the digits, i.e., either short (4-sec or long (16-sec. Our findings suggest that long empty intervals (16-sec are associated with a relative underestimation of duration, and to a feeling that the time passes slowly, a seemingly paradoxical result. Also, regarding more mindful individuals, such a dissociation between duration estimation and passage of time judgments was also found, but only when empty intervals were short (4-sec. Relatively speaking, more mindful subjects showed an increased overestimation of durations, but felt that time passed more quickly. These results provide further evidence for the dissociation between duration estimation and the feeling of the passage of time. We discuss these results in terms of an alerting effect when empty intervals are short and events are more numerous, which could mediate the effect of dispositional mindfulness.

  13. Learning Chemical Kinetics with Spreadsheets.

    Science.gov (United States)

    Blickensderfer, Roger

    1990-01-01

    Presented are several simple kinetic systems together with the spreadsheets used to solve them. A set of exercises in chemical kinetics appropriate for an introductory course in physical chemistry is given. Error propagation calculations with experimental data are illustrated. (CW)

  14. Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a in Mice

    Directory of Open Access Journals (Sweden)

    Rosie Z Yu

    2016-01-01

    Full Text Available Triantennary N-acetyl galactosamine (GalNAc3-conjugated antisense oligonucleotides (ASOs have greatly improved potency via receptor-mediated uptake. In the present study, the in vivo pharmacology of a 2′-O-(2-methoxyethyl-modified ASO conjugated with GalNAc3 (ISIS 681257 together with its unmodified congener (ISIS 494372 targeting human apolipoprotein (a (apo(a, were studied in human LPA transgenic mice. Further, the disposition kinetics of ISIS 681257 was studied in CD-1 mice. ISIS 681257 demonstrated over 20-fold improvement in potency over ISIS 494372 as measured by liver apo(a mRNA and plasma apo(a protein levels. Following subcutaneous (SC dosing, ISIS 681257 cleared rapidly from plasma and distributed to tissues. Intact ISIS 681257 was the major full-length oligonucleotide species in plasma. In tissues, however, GalNAc sugar moiety was rapidly metabolized and unconjugated ISIS 681257 accounted > 97% of the total exposure, which was then cleared slowly from tissues with a half-life of 7–8 days, similar to the half-life in plasma. ISIS 681257 is highly bound to plasma proteins (> 94% bound, which limited its urinary excretion. This study confirmed dose-dependent exposure to the parent drug ISIS 681257 in plasma and rapid conversion to unconjugated ASO in tissues. Safety data and the extended half-life support its further development and weekly dosing in phase 1 clinical studies.

  15. Simultaneous determination of rosuvastatin and amlodipine in human plasma using tandem mass spectrometry: Application to disposition kinetics

    Directory of Open Access Journals (Sweden)

    Anjaneyulu Narapusetti

    2015-11-01

    Full Text Available The liquid chromatography–tandem mass spectrometric assay method for the simultaneous determination of rosuvastatin and amlodipine in human plasma using deuterated analogs as internal standards has been developed and validated. The analytes were extracted from 100 μL aliquots of human plasma via liquid–liquid extraction using a mixture of ethyl acetate and n-hexane (80:20, v/v as an extraction solvent. The optimized mobile phase was composed of 0.1% formic acid in 5 mM ammonium acetate, methanol, and acetonitrile (20:20:60, v/v/v and delivered at a flow rate of 0.75 mL/min. The calibration curve obtained was linear (R2 ⩾ 0.999 over the concentration range of 0.52–51.77 ng/mL for rosuvastatin and 0.10–10.07 ng/mL for amlodipine. A sample turnover rate of less than 2.5 min makes it an attractive procedure in high-throughput bioanalysis of rosuvastatin and amlodipine. The present method was found to be applicable to clinical studies and the results were authenticated by incurred sample reanalysis.

  16. [Dispositional optimism and acceptance of illness among a group of individuals with Graves-Basedow's disease].

    Science.gov (United States)

    Basińska, Małgorzata Anna; Zalewska-Rydzkowska, Danuta; Wolańska, Paulina; Junik, Roman

    2008-01-01

    Dispositional optimism is a general tendency to positively perceive the world and one's own future. We can consider what kind of connection with ability to cope with difficulties. One situation which is very stressful for an individual is an illness, particularly a chronic one. The aim of the paper was to define the connection between dispositional optimism and acceptance of illness among the group with Graves-Basedow disease. This is autoimmunizational illness and diseases of this kind are particularly sensitive to the influence of psychological factors, as there are many connections between the immune system and the human psyche. The study group consisted of 59 individuals with Graves-Basedow disease, 50 women and 9 men and 55 of healthy ones, 49 women and 6 men according to age, sex and a level of education. The patients filled out three psychological questionnaires: The Life Orientation Test-Revised (LOT-R), The Acceptance of Illness Scale (AIS) and The Personal Questionnaire. of the study in question indicate a lack of differences between individuals with Graves-Basedow disease and healthy ones concerning the level of dispositional optimism. There no differences in the level of dispositional optimism as regards of criterion of health: by the levels of hormones TSH, fT3 and fT4, complications and a time of duration of disease. Instead, if they suffer additionally from others diseases, they have a lower level of dispositional optimism. There exist a connection between intensification of level of dispositional optimism and acceptance of illness among testing group. The dispositional optimism as a supply of individual helps her or his in adaptation to difficulty situation, which is a chronic disease. It is a reason way it is worth to help of patients to grow it stronger.

  17. Exploring the association between parental rearing styles and medical students' critical thinking disposition in China.

    Science.gov (United States)

    Huang, Lei; Wang, Zhaoxin; Yao, Yuhong; Shan, Chang; Wang, Haojie; Zhu, Mengyi; Lu, Yuan; Sun, Pengfei; Zhao, Xudong

    2015-05-14

    Critical thinking is an essential ability for medical students. However, the relationship between parental rearing styles and medical students' critical thinking disposition has rarely been considered. The aim of this study was to investigate whether parental rearing styles were significant predictors of critical thinking disposition among Chinese medical students. 1,075 medical students from the first year to the fifth year attending one of three medical schools in China were recruited via multistage stratified cluster sampling. The Chinese Critical Thinking Disposition Inventory(CTDI-CV) and The Egna Minnen av Barndoms Uppfostran (EMBU) questionnaire were applied to collect data and to conduct descriptive analysis. Stepwise multiple linear regression was used to analyze the data. The critical thinking disposition average mean score was 287.44 with 632 participants (58.79%) demonstrating positive critical thinking disposition. Stepwise multiple linear regression analysis revealed that the rearing styles of fathers, including "overprotection", "emotional warmth and understanding", "rejection" and "over-interference" were significant predictors of medical students' critical thinking disposition that explained 79.0% of the variance in critical thinking ability. Rearing styles of mothers including "emotional warmth and understanding", "punishing" and "rejection" were also found to be significant predictors, and explained 77.0% of the variance. Meaningful association has been evidenced between parental rearing styles and Chinese medical students' critical thinking disposition. Parental rearing styles should be considered as one of the many potential determinant factors that contribute to the cultivation of medical students' critical thinking capability. Positive parental rearing styles should be encouraged in the cultivation of children's critical thinking skills.

  18. Photon kinetics in plasmas

    Directory of Open Access Journals (Sweden)

    V.G. Morozov

    2009-01-01

    Full Text Available We present a kinetic theory of radiative processes in many-component plasmas with relativistic electrons and nonrelativistic heavy particles. Using the non-equilibrium Green's function technique in many-particle QED, we show that the transverse field correlation functions can be naturally decomposed into sharply peaked (non-Lorentzian parts that describe resonant (propagating photons and off-shell parts corresponding to virtual photons in the medium. Analogous decompositions are obtained for the longitudinal field correlation functions and the correlation functions of relativistic electrons. We derive a kinetic equation for the resonant photons with a finite spectral width and show that the off-shell parts of the particle and field correlation functions are essential to calculate the local radiating power in plasmas and recover the results of vacuum QED. The plasma effects on radiative processes are discussed.

  19. Prediction of pre-exam state anxiety from ruminative disposition: The mediating role of impaired attentional disengagement from negative information.

    Science.gov (United States)

    Vălenaş, Sergiu P; Szentágotai-Tătar, Aurora; Grafton, Ben; Notebaert, Lies; Miu, Andrei C; MacLeod, Colin

    2017-04-01

    Rumination is a maladaptive form of repetitive thinking that enhances stress responses, and heightened disposition to engage in rumination may contribute to the onset and persistence of stress-related symptoms. However, the cognitive mechanisms through which ruminative disposition influences stress reactivity are not yet fully understood. This study investigated the hypothesis that the impact of ruminative disposition on stress reactivity is carried by an attentional bias reflecting impaired attentional disengagement from negative information. We examined the capacity of a measure of ruminative disposition to predict both attentional biases to negative exam-related information, and state anxiety, in students approaching a mid-term exam. As expected, ruminative disposition predicted state anxiety, over and above the level predicted by trait anxiety. Ruminative disposition also predicted biased attentional disengagement from, but not biased attentional engagement with, negative information. Importantly, biased attentional disengagement from negative information mediated the relation between ruminative disposition and state anxiety. These findings confirm that dispositional rumination is associated with difficulty disengaging attention from negative information, and suggest that this attentional bias may be one of the mechanisms through which ruminative disposition influences stress reactivity. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Kinetics of phase change

    Directory of Open Access Journals (Sweden)

    A.C. Faleiros

    2000-07-01

    Full Text Available The kinetic model for change of phases developed by M. Avrami at the end of the thirties has been used to describe the temporal behavior of phase changes. Until today this model is studied and adapted to include broader hypotheses. However, the mathematical format presented by M. Avrami is difficult to be understood by beginners. The purpose of this work is to clarify the mathematical treatment of Avrami's work, going straightforward to the arguments that led to his main results.

  1. Rapid mixing kinetic techniques.

    Science.gov (United States)

    Martin, Stephen R; Schilstra, Maria J

    2013-01-01

    Almost all of the elementary steps in a biochemical reaction scheme are either unimolecular or bimolecular processes that frequently occur on sub-second, often sub-millisecond, time scales. The traditional approach in kinetic studies is to mix two or more reagents and monitor the changes in concentrations with time. Conventional spectrophotometers cannot generally be used to study reactions that are complete within less than about 20 s, as it takes that amount of time to manually mix the reagents and activate the instrument. Rapid mixing techniques, which generally achieve mixing in less than 2 ms, overcome this limitation. This chapter is concerned with the use of these techniques in the study of reactions which reach equilibrium; the application of these methods to the study of enzyme kinetics is described in several excellent texts (Cornish-Bowden, Fundamentals of enzyme kinetics. Portland Press, 1995; Gutfreund, Kinetics for the life sciences. Receptors, transmitters and catalysis. Cambridge University Press, 1995).There are various ways to monitor changes in concentration of reactants, intermediates and products after mixing, but the most common way is to use changes in optical signals (absorbance or fluorescence) which often accompany reactions. Although absorbance can sometimes be used, fluorescence is often preferred because of its greater sensitivity, particularly in monitoring conformational changes. Such methods are continuous with good time resolution but they seldom permit the direct determination of the concentrations of individual species. Alternatively, samples may be taken from the reaction volume, mixed with a chemical quenching agent to stop the reaction, and their contents assessed by techniques such as HPLC. These methods can directly determine the concentrations of different species, but are discontinuous and have a limited time resolution.

  2. Kinetic transport in crystals

    OpenAIRE

    Marklof, Jens

    2009-01-01

    One of the central challenges in kinetic theory is the derivation of macroscopic evolution equations--describing, for example, the dynamics of an electron gas--from the underlying fundamental microscopic laws of classical or quantum mechanics. An iconic mathematical model in this research area is the Lorentz gas, which describes an ensemble of non-interacting point particles in an infinite array of spherical scatterers. In the case of a disordered scatterer configuration, the classical result...

  3. Plasma and Ocular Prednisolone Disposition after Oral Treatment in Cats

    Directory of Open Access Journals (Sweden)

    María J. Del Sole

    2013-01-01

    Full Text Available Objective. To evaluate the plasma and aqueous humor disposition of prednisolone after oral administration in cats. Methods. Six cats were administered with a single oral dose of prednisolone (10 mg. Blood and aqueous humor samples were serially collected after drug administration. Prednisolone concentrations in plasma and aqueous humor were measured at 0.25, 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, and 5.0 h after administration by a high-performance liquid chromatographic analytical method developed and validated for this purpose. Results. Mean ± standard error (SE of maximum plasma prednisolone concentration (300.8 ± 67.3 ng/mL was reached at 1 h after administration. Prednisolone was distributed to the aqueous humor reaching a mean peak concentration of 100.9 ± 25.5 ng/mL at 1.25 h after administration. The mean ± SE systemic and aqueous humor exposure (AUC was 553.3 ± 120.0 ng*h/mL and 378.8 ± 64.9 ng*h/mL, respectively. A high AUCaqueous humor/AUCplasma ratio was observed (0.68 ± 0.13. The mean half-life time of elimination in plasma and aqueous humor was 0.87 ± 0.16 h and 2.25 ± 0.44 h, respectively. Clinical Significance. The observed high ratio between aqueous humor and plasma prednisolone concentrations indicates that extensive penetration of prednisolone to the anterior segment of the eye may occur. This is the first step that contributes to the optimization of the pharmacological therapeutics for the clinical treatment of uveitis.

  4. Assessing the association between thinking dispositions and clinical error.

    Science.gov (United States)

    Kinnear, John; Wilson, Nick

    2017-08-09

    Dual-process theory suggests that type 1 thinking results in a propensity to make 'intuitive' decisions based on limited information. Type 2 processes, on the other hand, are able to analyse these initial responses and replace them with rationalised decisions. Individuals may have a preference for different modes of rationalisation, on a continuum from careful to cursory. These 'dispositions' of thinking reside in type 2 processes and may result in error when the preference is for 'quick and casual' decision-making. We asked clinicians to answer a cognitive puzzle to which there was an obvious, but incorrect, answer, to measure their propensity for 'quick and casual' decision-making. The same clinicians were also asked to report the number of clinical errors they had committed in the previous two weeks. We hypothesised an association between committing error and settling for an incorrect answer, and that the cognitive puzzle would have predictive capability. 90 of 153 (59%) clinicians reported that they had committed error, while 103 (67%) gave the incorrect 'intuitive' answer to the cognitive puzzle. There was no statistically significant difference between clinicians who committed error and answered incorrectly, and those who did not and answered correctly (χ 2 (1, n=1153)=0.021, p=0.885). The prevalence of clinical error in our study was higher than previously reported in the literature, and the propensity for accepting intuitive solutions was high. Although the cognitive puzzle was unable to predict who was more likely to commit error, the study offers insights into developing other predictive models for error. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  5. Assessment of DOE radioactive scrap metal disposition options

    Energy Technology Data Exchange (ETDEWEB)

    Butler, C.R.; Kasper, K.M. [Waste Policy Institute, Morgantown, WV (United States); Bossart, S.J. [Department of Energy, Morgantown, WV (United States)

    1997-02-01

    The DOE has amassed a large amount of radioactively-contaminated scrap metal (RSM) as a result of past operations and decontamination and decommissioning (D&D) projects. The volume of RSM will continue to increase as a result of the D&D of more than 6,000 surplus facilities and many of the 14,000 operating facilities in the DOE complex. RSM can be either surface contaminated or volumetrically contaminated, or both, with varying amounts of radioactivity. Several options exist for the disposition of this RSM, including disposal as radioactive waste, recycling by decontamination and free-release for unrestricted use, or recycling for restricted reuse inside a DOE controlled area. The DOE Office of Science and Technology (EM-50) has been actively investing in technology and strategy development in support of restricted-reuse RSM recycling for the past several years. This paper will assess the nature of the RSM recycling issue, review past investment by DOE to develop technologies and strategies to recycle RSM, and then discuss some recommendations concerning future investments in support of RSM management. Available information on the supply of RSM will be presented in Section II. The regulatory and policy framework concerning recycling RSM will be presented in Section III. A review of DOE investment in RSM recycling technology and current programs will be presented in Section IV. The current and projected industrial capacity will be described in Section V. And, finally, a discussion of issues and recommendations regarding DOE technology development interests in RSM recycling will be presented in Section VI and VII, respectively.

  6. The disposition index: from individual to population approach.

    Science.gov (United States)

    Denti, Paolo; Toffolo, Gianna Maria; Cobelli, Claudio

    2012-09-01

    To correctly evaluate the glucose control system, it is crucial to account for both insulin sensitivity and secretion. The disposition index (DI) is the most widely accepted method to do so. The original paradigm (hyperbolic law) consists of the multiplicative product of indices related to insulin sensitivity and secretion, but more recently, an alternative formula has been proposed with the exponent α (power function law). Traditionally, curve-fitting approaches have been used to evaluate the DI in a population: the algorithmic implementations often introduce some critical issues, such as the assumption that one of the two indices is error free or the effects of the log transformation on the measurement errors. In this work, we review the commonly used approaches and show that they provide biased estimates. Then we propose a novel nonlinear total least square (NLTLS) approach, which does not need to use the approximations built in the previously proposed alternatives, and show its superiority. All of the traditional fit procedures, including NLTLS, account only for uncertainty affecting insulin sensitivity and secretion indices when they are estimated from noisy data. Thus, they fail when part of the observed variability is due to inherent differences in DI values between individuals. To handle this inevitable source of variability, we propose a nonlinear mixed-effects approach that describes the DI using population hyperparameters such as the population typical values and covariance matrix. On simulated data, this novel technique is much more reliable than the curve-fitting approaches, and it proves robust even when no or small population variability is present in the DI values. Applying this new approach to the analysis of real IVGTT data suggests a value of α significantly smaller than 1, supporting the importance of testing the power function law as an alternative to the simpler hyperbolic law.

  7. Evaluation of used fuel disposition in clay-bearing rock

    Energy Technology Data Exchange (ETDEWEB)

    Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hammond, Glenn Edward [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kuhlman, Kristopher L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Zheng, Liange [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kim, Kunhwi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Xu, Hao. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rutqvist, Jonny [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Caporuscio, Florie Andre [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Norskog, Katherine E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Maner, James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Palaich, Sarah [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cheshire, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavarin, Mavrik [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolery, Thomas J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Atkins-Duffin, Cindy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jerden, James L. [Argonne National Lab. (ANL), Argonne, IL (United States); Copple, Jacqueline M. [Argonne National Lab. (ANL), Argonne, IL (United States); Cruse, Terry [Argonne National Lab. (ANL), Argonne, IL (United States); Ebert, William L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-01

    The R&D program from the DOE Used Fuel Disposition Campaign (UFDC) has documented key advances in coupled Thermal-Hydrological-Mechanical-Chemical (THMC) modeling of clay to simulate its complex dynamic behavior in response to thermal and hydrochemical feedbacks. These efforts have been harnessed to assess the isolation performance of heat-generating nuclear waste in a deep geological repository in clay/shale/argillaceous rock formations. This report describes the ongoing disposal R&D efforts on the advancement and refinement of coupled THMC process models, hydrothermal experiments on barrier clay interactions, used fuel and canister material degradation, thermodynamic database development, and reactive transport modeling of the near-field under non-isothermal conditions. These play an important role to the evaluation of sacrificial zones as part of the EBS exposure to thermally-driven chemical and transport processes. Thermal inducement of chemical interactions at EBS domains enhances mineral dissolution/precipitation but also generates mineralogical changes that result in mineral H2O uptake/removal (hydration/dehydration reactions). These processes can result in volume changes that can affect the interface / bulk phase porosities and the mechanical (stress) state of the bentonite barrier. Characterization studies on bentonite barrier samples from the FEBEX-DP international activity have provided important insight on clay barrier microstructures (e.g., microcracks) and interactions at EBS interfaces. Enhancements to the used fuel degradation model outlines the need to include the effects of canister corrosion due the strong influence of H2 generation on the source term.

  8. Methamphetamine disposition in oral fluid, plasma, and urine.

    Science.gov (United States)

    Huestis, Marilyn A; Cone, Edward J

    2007-03-01

    This review of the disposition of methamphetamine in oral fluid, plasma, and urine is based on a comprehensive controlled dosing study involving five healthy, drug-free research volunteers who resided on a closed clinical ward for 12 weeks. Subjects were administered four low (10 mg) and high (20 mg) daily oral doses of methamphetamine in two separate sessions. Near-simultaneous collections of oral fluid and plasma were performed on the first day of each low- and high-dose session. Thereafter, oral fluid was provided on each day of dosing by different oral fluid collection methods. All urine specimens were collected on an ad libitum basis throughout the study. Specimens were analyzed by gas-chromatography mass spectrometry for methamphetamine and the metabolite, amphetamine, with a limit of quantification of 2.5 ng/mL for each analyte. Methamphetamine and metabolite concentrations in oral fluid appeared to follow a similar time course in oral fluid as in plasma and were dose-proportional, but oral fluid concentrations exceeded plasma concentrations. Urine drug concentrations were substantially higher than those in oral fluid. Some drug accumulation was noted with daily dosing, but generally did not markedly influence detection times or detection rates of oral fluid tests. Detection times and detection rates for oral fluid and urine were determined at cessation of 4 days of dosing. Generally, detection times and rates for urine were longer than those observed for oral fluid at conventional cutoff concentrations. When contemplating selection of oral fluid as a test matrix, the advantages of oral fluid collection should be weighed against its shorter time of detection compared to that of urine.

  9. Calcite Dissolution Kinetics

    Science.gov (United States)

    Berelson, W.; Subhas, A.; Dong, S.; Naviaux, J.; Adkins, J. F.

    2016-12-01

    A geological buffer for high atmospheric CO2 concentrations is neutralization via reaction with CaCO3. We have been studying the dissolution kinetics of carbonate minerals using labeled 13C calcite and Picarro-based measurements of 13C enrichments in solution DIC. This methodology has greatly facilitated our investigation of dissolution kinetics as a function of water carbonate chemistry, temperature and pressure. One can adjust the saturation state Omega by changing the ion activity product (e.g. adjusting carbonate ion concentration), or by changing the solubility product (e.g. adjusting temperature or pressure). The canonical formulation of dissolution rate vs. omega has been refined (Subhas et al. 2015) and shows distinct non-linear behavior near equilibrium and rates in sea water of 1-3 e-6 g/cm2day at omega = 0.8. Carbonic anhydrase (CA), an enzyme that catalyzes the hydration of dissolved CO2 to carbonic acid, was shown (in concentrations rate at low degrees of undersaturation by >500x. This result points to the importance of carbonic acid in enhancing dissolution at low degrees of undersaturation. CA activity and abundance in nature must be considered regarding the role it plays in catalyzing dissolution. We also have been investigating the role of temperature on dissolution kinetics. An increase of 16C yields an order of magnitude increase in dissolution rate. Temperature (and P) also change Omega critical, the saturation state where dissolution rates change substantially. Increasing pressure (achieved in a pressure reaction chamber we built) also shifts Omega critical closer to equilibrium and small pressure increases have large impact on dissolution kinetics. Dissolution rates are enhanced by an order of magnitude for a change in pressure of 1500 psi relative to the dissolution rate achieved by water chemistry effects alone for an omega of 0.8. We've shown that the thermodynamic determination of saturation state does not adequately describe the kinetics

  10. Development of an automated multiple-target mask CD disposition system to enable new sampling strategy

    Science.gov (United States)

    Ma, Jian; Farnsworth, Jeff; Bassist, Larry; Cui, Ying; Mammen, Bobby; Padmanaban, Ramaswamy; Nadamuni, Venkatesh; Kamath, Muralidhar; Buckmann, Ken; Neff, Julie; Freiberger, Phil

    2006-03-01

    Traditional mask critical dimension (CD) disposition systems with only one or two targets is being challenged by the new requirements from mask-users as the wafer process control becomes more complicated in the newer generation of technologies. Historically, the mask shop does not necessarily measure and disposition off the same kind of CD structures that wafer fabs do. Mask disposition specifications and structures come from the frame-design and the tapeout, while wafer-level CD dispositions are mainly based on the historical process window established per CD-skew experiments and EOL (end of line) yield. In the current high volume manufacturing environment, the mask CDs are mainly dispositioned off their mean-to-target (MTT) and uniformity (6sigma) on one or two types of pre-determined structures. The disposition specification is set to ensure the printed mask will meet the design requirements and to ensure minimum deviation from them. The CD data are also used to adjust the dose of the mask exposure tools to control CD MTT. As a result, the mask CD disposition automation system was built to allow only one or two kinds of targets at most. In contrast, wafer-fabs measure a fairly wide range of different structures to ensure their process is on target and in control. The number of such structures that are considered critical is increasing due the growing complexity of the technology. To fully comprehend the wafer-level requirements, it is highly desirable to align the mask CD sample site and disposition to be the same as that of the wafer-fabs, to measure the OPC (optical proximity correction) structures or equivalent whenever possible, and to establish the true correlation between mask CD measurements vs. wafer CD measurement. In this paper, the development of an automated multiple-target mask CD disposition system with the goal of enabling new sampling strategy is presented. The pros and cons of its implementation are discussed. The new system has been inserted in

  11. Core self-evaluations mediate the associations of dispositional optimism and life satisfaction.

    Directory of Open Access Journals (Sweden)

    Wensheng Jiang

    Full Text Available BACKGROUND: Positive traits, such as life satisfaction, optimism, and core self-evaluation (CSE, have garnered increasing attention from researchers and professionals. However, the trilateral relationship among them remains unclear. OBJECTIVE: This study examines the effect of dispositional optimism on life satisfaction and primarily verified the mediator role of CSEs. METHODS: Six hundred thirty college students from two general universities completed a questionnaire packet containing life orientation test-revised (LOT-R, core self-evaluations, and satisfaction with life scale. Confirmatory factor analysis (CFA was conducted to assess the dimension of LOT-R. Bootstrap was used in structural equation modeling to analyze mediation effect. RESULTS: Results revealed that dispositional optimism and core self-evaluations were significantly correlated with life satisfaction. CFA identified the bidimensional structure of dispositional optimism. SEM indicated that core self-evaluations partially mediated the effect of dispositional optimism on life satisfaction. The final model also revealed significant paths from optimism and pessimism to life satisfaction through core-self evaluations. CONCLUSION: The findings extended prior studies and shed light on how dispositional optimism influences life satisfaction. This study provides valuable evidence on how to promote the life satisfaction of human beings in positive psychology. A further study can fully explore the relationship among them in multi-cultural follow-up studies.

  12. Core self-evaluations mediate the associations of dispositional optimism and life satisfaction.

    Science.gov (United States)

    Jiang, Wensheng; Li, Fei; Jiang, Haipeng; Yu, Lili; Liu, Wenbo; Li, Qiang; Zuo, Luning

    2014-01-01

    Positive traits, such as life satisfaction, optimism, and core self-evaluation (CSE), have garnered increasing attention from researchers and professionals. However, the trilateral relationship among them remains unclear. This study examines the effect of dispositional optimism on life satisfaction and primarily verified the mediator role of CSEs. Six hundred thirty college students from two general universities completed a questionnaire packet containing life orientation test-revised (LOT-R), core self-evaluations, and satisfaction with life scale. Confirmatory factor analysis (CFA) was conducted to assess the dimension of LOT-R. Bootstrap was used in structural equation modeling to analyze mediation effect. Results revealed that dispositional optimism and core self-evaluations were significantly correlated with life satisfaction. CFA identified the bidimensional structure of dispositional optimism. SEM indicated that core self-evaluations partially mediated the effect of dispositional optimism on life satisfaction. The final model also revealed significant paths from optimism and pessimism to life satisfaction through core-self evaluations. The findings extended prior studies and shed light on how dispositional optimism influences life satisfaction. This study provides valuable evidence on how to promote the life satisfaction of human beings in positive psychology. A further study can fully explore the relationship among them in multi-cultural follow-up studies.

  13. Dispositional resilience as a moderator of the relationship between chronic stress and irregular menstrual cycle.

    Science.gov (United States)

    Palm-Fischbacher, Simona; Ehlert, Ulrike

    2014-06-01

    Menstrual-cycle irregularity may have an important influence on the subsequent development of chronic diseases. Several risk factors for irregular menstrual cycles have been detected, including stress. Our aim was to extend research on the link between chronic stress and menstrual-cycle irregularity and to assess potential protective factors, such as dispositional resilience, which we hypothesize to be associated with the maintenance or promotion of a healthy menstrual cycle. For this cross-sectional study, data on 696 healthy women aged 20-40 years were obtained. The women completed measures of chronic stress, dispositional resilience and menstrual-cycle irregularity. Furthermore, potential confounds were assessed. Of the participants, 383 (55%) reported no current use of hormonal contraceptives; 313 (45%) reported current use hormonal contraception and were included as a control group. The results suggest that in women not using hormonal contraception, chronic stress (OR = 1.05, 95%CI = 1.02-1.08, p = 0.001) and dispositional resilience (OR = 0.43, 95%CI = 0.31-0.59, p menstrual cycle regularity. In addition, women with greater dispositional resilience have reduced risk for irregular menstrual cycles in the face of low to moderate chronic stress; however, this association is changed at the highest level of chronic stress. These findings suggest that dispositional resilience may be a protective psychological trait that modulates reproductive functioning.

  14. Profiles of Dispositional Expectancies and Affectivity Predict Later Psychosocial Functioning in Children and Adolescents With Cancer.

    Science.gov (United States)

    Okado, Yuko; Howard Sharp, Katianne M; Tillery, Rachel; Long, Alanna M; Phipps, Sean

    2016-04-01

    Examined how individual differences in disposition among pediatric cancer patients predict their later psychosocial functioning. Patients aged 8-17 years (N = 223) reported on their disposition at baseline. One and three years later, self-reports and parent reports of patient psychosocial functioning were obtained. Latent profile analysis was used to identify subgroups that differed on baseline disposition and to compare them on later outcomes. Three groups were identified: The "Positive" group (59%) had high optimism and positive affectivity and low pessimism and negative affectivity; the "Moderate" group (39%) had a similar profile, with less exaggerated scores; a small, "Negative" group (2%) had the opposite profile (low optimism/positive affectivity; high pessimism/negative affectivity). These groups differed in psychosocial functioning at follow-up, generally in expected directions. Most patients have a disposition that may be protective. A small minority at high risk for maladjustment is distinguished by their disposition. © The Author 2015. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Dispositional sources of sanction perceptions: Emotionality, cognitive style, intolerance of ambiguity, and self-efficacy.

    Science.gov (United States)

    Pickett, Justin T; Bushway, Shawn D

    2015-12-01

    This study contributes to efforts to identify the sources of arrest risk perceptions and ambiguity (or lack of confidence) in such perceptions. Drawing on dual-process theories of reasoning, we argue that arrest risk perceptions often represent intuitive judgments that are influenced by cognitive heuristics and dispositional attributes. Multivariate regression models are estimated with data from 3 national surveys to test 6 hypotheses about the relationships between specific dispositional attributes and perceived arrest risk and ambiguity. We find evidence that dispositional positive affect and intolerance of ambiguity are both positively related to perceived arrest risk, and are also both negatively related to ambiguity. We also find evidence that cognitive reflection and general self-efficacy are, respectively, positively and negatively associated with ambiguity. Mixed evidence emerges about whether cognitive reflection is related to risk perceptions, and about whether either dispositional negative affect or thoughtfully reflective decision making correlate with ambiguity. Taken together, the results provide partial support for each of our hypotheses, and suggest that dispositional attributes are important sources of perceptions of arrest risk as well as of ambiguity in such perceptions. (c) 2015 APA, all rights reserved).

  16. The Relationship between Values and Critical Thinking Dispositions of Pre-Service Teachers

    Directory of Open Access Journals (Sweden)

    Mustafa Volkan Coskun

    2016-12-01

    Full Text Available This study aimed to reveal the relationship between personality values and critical thinking disposition of pre-service teachers studying in a Faculty of Education. The study was designed using the survey model. The population of this study consisted of pre-service teachers studying at the Faculty of Education at Mugla Sitki Kocman University, Turkey, during the 2015-2016 academic year. The sample of the study consisted of 570 pre-service teachers who were selected by using disproportionate cluster sampling technique. The data of the study were obtained through the administration of the Florida Critical Disposition Scale (UF/EMI and University Students Values Scale (USVS. USVS was developed within the scope of the present study. Descriptive statistics, t-test, ANOVA, and multivariate regression analysis were used to analyze the data. The study revealed that the pre-service teachers attributed highest value to sensitivity. These values were identified to be followed with respect to diversity, trustability, and responsibility. In addition, the level of students’ critical thinking dispositions was found to be at the average level. Furthermore, the values of students explained approximately one-third of the critical-thinking dispositions. The values of sensitivity, responsibility and respect for diversity were determined to be the significant predictors of students’ critical-thinking dispositions.

  17. Low dispositional mindfulness predicts self-medication of negative emotion with prescription opioids.

    Science.gov (United States)

    Garland, Eric L; Hanley, Adam W; Thomas, Elizabeth A; Knoll, Paul; Ferraro, Jeffrey

    2015-01-01

    Although evidence is mounting that opioids are abused to self-medicate negative emotions, little is known about the traits and factors linked to opioid self-medication. One potentially crucial psychological correlate is dispositional mindfulness. Thus, the purpose of this study was to describe the prevalence of opioid self-medication among a treatment-seeking sample of prescription opioid-dependent individuals and specifically examine the relationship between dispositional mindfulness and opioid self-medication. Participants in acute detoxification or intensive outpatient treatment for prescription opioid dependence (n = 79) were recruited from a regional hospital's addictions treatment unit for this cross-sectional study. Sociodemographic data were collected along with surveys of opioid self-medication, pain level, and dispositional mindfulness. Self-medication of negative affective states with opioids was quite common, with 94.9% of individuals sampled reporting self-medication behaviors. In adjusted analyses, individuals engaging in more frequent opioid use tended to self-medicate negative emotions with opioids more often than those engaging in more intermittent opioid use (β = 0.33; P self-medication (β = -0.42; P Self-medication of negative emotions with opioids was prevalent in this sample and related to low dispositional mindfulness. Plausibly, increasing mindfulness may decrease opioid self-medication. Addictive automaticity and emotion regulation are discussed as potential mechanisms linking low dispositional mindfulness and self-medication.

  18. Dispositional envy revisited: unraveling the motivational dynamics of benign and malicious envy.

    Science.gov (United States)

    Lange, Jens; Crusius, Jan

    2015-02-01

    Previous research has conceptualized dispositional envy as a unitary construct. Recently however, episodic envy has been shown to emerge in two qualitatively different forms. Benign envy is related to the motivation to move upward, whereas malicious envy is related to pulling superior others down. In four studies (N = 1,094)--using the newly developed Benign and Malicious Envy Scale (BeMaS)--we show that dispositional envy is also characterized by two independent dimensions related to distinct motivational dynamics and behavioral consequences. Dispositional benign and malicious envy uniquely predict envious responding following upward social comparisons. Furthermore, they are differentially connected to hope for success and fear of failure. Corresponding to these links, dispositional benign envy predicted faster race performance of marathon runners mediated via higher goal setting. In contrast, dispositional malicious envy predicted race goal disengagement. The findings highlight that disentangling the two sides of envy opens up numerous research avenues. © 2014 by the Society for Personality and Social Psychology, Inc.

  19. Does Body Mass Index Influence Behavioral Regulations, Dispositional Flow and Social Physique Anxiety in Exercise Setting?

    Science.gov (United States)

    Ersöz, Gözde; Altiparmak, Ersin; Aşçı, F Hülya

    2016-06-01

    The purpose of this study was to examine differences in behavioral regulations, dispositional flow, social physique anxiety of exercisers in terms of body mass index (BMI). 782 university students participated in this study. Dispositional Flow State Scale-2, Behavioral Regulations in Exercise Questionnaire-2, Social Physique Anxiety Scale and Physical Activity Stages of Change Questionnaire were administered to participants. After controlling for gender, analysis indicated significant differences in behavioral regulations, dispositional flow and social physique anxiety of exercise participants with regards to BMI. In summary, the findings demonstrate that normal weighted participants exercise for internal reasons while underweighted participants are amotivated for exercise participation. Additionally, participants who are underweight had higher dispositional flow and lower social physique anxiety scores than other BMI classification. Key pointsNormal weighted participants exercise for internal reasons.Underweighted participants are amotivated for exercise participation.Underweighted participants had higher dispositional flow.Underweighted participants have lower social physique anxiety scores than normal weighted, overweight and obese participants.

  20. Situational and dispositional goal adjustment in the context of metastatic cancer.

    Science.gov (United States)

    Thompson, Elizabeth; Stanton, Annette L; Bower, Julienne E

    2013-10-01

    Striving toward goals is associated with higher levels of subjective well-being; however, many potential roadblocks to goal achievement exist. The current study extends the understanding of goal regulation processes in its examination of the relationships between dispositional and situational goal adjustment to a profound stressor and their associations with psychological adjustment. Women (N = 103; M age = 57.2 years; 82% Caucasian) with metastatic breast cancer completed semistructured interviews and self-report measures at study entry and 3 months later. Measures of dispositional and situational goal reengagement were significantly correlated, but dispositional and situational goal disengagement were unrelated. Greater dispositional and situational goal disengagement abilities were associated with fewer cancer-related intrusive thoughts at Time 1. Dispositional and situational reengagement were positively associated with life satisfaction and sense of purpose and negatively associated with depressive symptoms at Time 1. However, greater initial situational goal disengagement predicted an increase in depressive symptoms over time. Both how an individual typically responds to goal blockage, as well as how an individual is currently responding to a specific blocked goal, appear related to psychological adjustment. © 2012 Wiley Periodicals, Inc.

  1. Disposition of excess weapon grade plutonium: Status of the Russian program

    Energy Technology Data Exchange (ETDEWEB)

    Diyakov, Anatoly [Center for Arms Control, Energy and Environmental Studies, Moscow (Russian Federation)

    2015-07-01

    During the Cold War, the Soviet Union and United States produced huge quantities of plutonium for weapons. Substantial cuts in their nuclear arsenals released of huge amounts of weapon grade nuclear materials. This put into the agenda the problem what to do with the excess weapon materials. In 2000 Russia and the United States concluded a Plutonium Management and Disposition Agreement (PMDA), committing each to eliminate 34 tons of excess weapon plutonium. It was expected that the implementation of the PMDA Agreement will start in the second half of the year 2009 and the disposition programs finalized in 2025. But from the very beginning the practical implementation of the PMDA agreement met with substantial difficulties. After the consultations held in 2006-2007 the PMDA Agreement was modified. In compliance with the modified Agreement each side pledged to start the disposition of 34 tons of excess plutonium (25 tons in the form of metal and 9 tons in dioxide) in 2018 and to finalize the process in 15 years. Both sides were supposed to use the same disposition method through use in the MOX fuel and its subsequent irradiation in civil nuclear reactors: in light reactors for the USA and in fast neutron reactors for Russia. The presentation is going to provide the current status of the disposition program.

  2. Searching for a Job on the Contemporary Labour Market: The Role of Dispositional Employability

    Directory of Open Access Journals (Sweden)

    Jasmina Tomas

    2017-03-01

    Full Text Available By acknowledging the uncertainty and unpredictability of the job search process in an unemployment setting, the present study explored the predictive strength of dispositional employability in job search behaviours. Dispositional employability has been recognized as a potentially important personal resource that promotes job opportunities. However, it has rarely been assessed in an unemployment setting to date. According to recent employability models that differentiate between distal (i.e., personal strengths and proximal (e.g., perceived employability determinants of behaviour on the labour market, we hypoth- esized that: (i dispositional employability relates positively to job search intensity and (ii perception of one’s employment possibilities (i.e., perceived employability serves as an explanatory mechanism of this relationship. The hypothesized structural model was tested among a heterogeneous sample of 533 unemployed persons in Croatia. The results of structural equation modelling provided support for our hypotheses: dispositional employability related positively to job search intensity via perceived employ- ability. Accordingly, nurturing dispositional employability may be beneficial for unemployed persons as it relates positively to engagement in job search behaviour.

  3. Dispositional Mindfulness and Aggression Among Women in Residential Substance Use Treatment.

    Science.gov (United States)

    Shorey, Ryan C; Elmquist, JoAnna; Anderson, Scott E; Stuart, Gregory L

    2015-01-01

    There is a large literature on substance misuse and interpersonal aggression, including aggression perpetrated by women in treatment for substance misuse. There is also a growing body of literature on mindfulness and substance use, as well as mindfulness and aggression. However, to date, there has been little research on whether dispositional mindfulness is associated with increased aggression among women in treatment for substance misuse. The current study, therefore, examined whether dispositional mindfulness was associated with aggression, above and beyond substance use and demographic characteristics, in women in residential substance misuse treatment (N = 137). Results showed that lower dispositional mindfulness was associated with increased aggression (physical, verbal, and aggressive attitude). Moreover, this relationship between dispositional mindfulness and aggression remained even after controlling for alcohol problems, drug problems, and age, all known predictors of aggression. Our results provide the first empirical evidence that dispositional mindfulness is negatively associated with aggression in women in treatment for substance misuse. Pending replication, this could have important implications for treatment. Specifically, mindfulness-based interventions may prove helpful for the concurrent treatment of substance misuse and aggression.

  4. Mathematical modeling analysis of intratumoral disposition of anticancer agents and drug delivery systems.

    Science.gov (United States)

    Popilski, Hen; Stepensky, David

    2015-05-01

    Solid tumors are characterized by complex morphology. Numerous factors relating to the composition of the cells and tumor stroma, vascularization and drainage of fluids affect the local microenvironment within a specific location inside the tumor. As a result, the intratumoral drug/drug delivery system (DDS) disposition following systemic or local administration is non-homogeneous and its complexity reflects the differences in the local microenvironment. Mathematical models can be used to analyze the intratumoral drug/DDS disposition and pharmacological effects and to assist in choice of optimal anticancer treatment strategies. The mathematical models that have been applied by different research groups to describe the intratumoral disposition of anticancer drugs/DDSs are summarized in this article. The properties of these models and of their suitability for prediction of the drug/DDS intratumoral disposition and pharmacological effects are reviewed. Currently available mathematical models appear to neglect some of the major factors that govern the drug/DDS intratumoral disposition, and apparently possess limited prediction capabilities. More sophisticated and detailed mathematical models and their extensive validation are needed for reliable prediction of different treatment scenarios and for optimization of drug treatment in the individual cancer patients.

  5. DISPOSITION EFFECT TERHADAP HUBUNGAN ANTARA NILAI FUNDAMENTAL DAN HARGA SAHAM PADA PERIODE KRISIS FINANSIAL

    Directory of Open Access Journals (Sweden)

    Yohanes Indrayono

    2017-03-01

    Full Text Available Stock price was positively affected by a change of company fundamental value which included profitability,growth, and dividend factors. Excess volatility hypothesis, on the other hand, indicated that stock price wastoo volatile correlated to its fundamental value. This study empirically investigated the moderating impact ofdisposition effect - the tendency to sell stocks that had appreciated in price (winners too soon and to hold stocksthat trade price below the purchase price (losers too long - on the relationship between fundamental values andstock prices. Fifty-three stocks of Indonesian Stock Exchange were chosen as the research sample based onsampling criteria for the periods before, during, and after the 2008 financial crisis. By using multiple regressionsanalyses, this study revealed that during these periods, disposition effect weakened the positive relationshipbetween earning per share and stock prices as well as between book value per share and stock prices. Thehigher the proportion of disposition investors, the less sensitive the stock price to the changes in fundamentalvariables. Unlike previous studies that investigated the direct impact of disposition effects on stock prices, thisstudy investigated the indirect impact of disposition effect on stock prices. Thus, this study contributed to theexisting behavioral finance literature by providing some useful insights into understanding why stock priceswere less sensitive to the changes in fundamental variables in the presence of disposition effect.

  6. Effect of caring behavior on disposition toward critical thinking of nursing students.

    Science.gov (United States)

    Pai, Hsiang-Chu; Eng, Cheng-Joo; Ko, Hui-Ling

    2013-01-01

    The purpose of this study was to explore the relationship between caring behavior and the disposition toward critical thinking of nursing students in clinical practice. A structural equation model was used to test the hypothesized relationship between caring behavior and critical thinking skills. Caring is the core of nursing practice, and the disposition toward critical thinking is needed for competent nursing care. In a fast-paced and complex environment, however, "caring" may be lost. Because nursing students will become professional nurses, it is essential to explore their caring behaviors and critical thinking skills and to understand how to improve their critical thinking skills based on their caring behavior. A cross-sectional study was used, with convenience sampling of students who were participating in associate degree nursing programs at 3 colleges of nursing. The following instruments were used: critical thinking disposition inventory Chinese version and caring behaviors scale. The study found that individuals with a higher frequency of caring behaviors had a higher score on critical thinking about nursing practice (β = .44, t = 5.14, P critical thinking. The findings of this study revealed the importance of caring behavior and its relationship with the disposition toward critical thinking. Thus, it is recommended that nursing education should emphasize a curriculum related to caring behavior to improve the disposition toward critical thinking of nursing students. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Dispositional Negativity in the Wild: Social Environment Governs Momentary Emotional Experience.

    Science.gov (United States)

    Shackman, Alexander J; Weinstein, Jennifer S; Hudja, Stanton N; Bloomer, Conor D; Barstead, Matthew G; Fox, Andrew S; Lemay, Edward P

    2017-06-12

    Dispositional negativity-the tendency to experience more frequent or intense negative emotions-is a fundamental dimension of temperament and personality. Elevated levels of dispositional negativity have profound consequences for public health and wealth, drawing the attention of researchers, clinicians, and policymakers. Yet, relatively little is known about the factors that govern the momentary expression of dispositional negativity in the real world. Here, we used smart phone-based experience-sampling to demonstrate that the social environment plays a central role in shaping the moment-by-moment emotional experience of 127 young adults selectively recruited to represent a broad spectrum of dispositional negativity. Results indicate that individuals with a more negative disposition derive much larger emotional benefits from the company of close companions-friends, romantic partners, and family members-and that these benefits reflect heightened feelings of social connection and acceptance. These results set the stage for developing improved interventions and provide new insights into the interaction of emotional traits and situations in the real world, close to clinically and practically important end-points. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  8. Uptake and disposition of select pharmaceuticals by bluegill exposed at constant concentrations in a flow-through aquatic exposure system

    Science.gov (United States)

    Zhao, Jian-Liang; Furlong, Edward T.; Schoenfuss, Heiko L.; Kolpin, Dana W.; Bird, Kyle L.; Feifarek, David J.; Schwab, Eric A.; Ying, Guang-Guo

    2017-01-01

    The increasing use of pharmaceuticals has led to their subsequent input into and release from wastewater treatment plants, with corresponding discharge into surface waters that may subsequently exert adverse effects upon aquatic organisms. Although the distribution of pharmaceuticals in surface water has been extensively studied, the details of uptake, internal distribution, and kinetic processing of pharmaceuticals in exposed fish have received less attention. For this research, we investigated the uptake, disposition, and toxicokinetics of five pharmaceuticals (diclofenac, methocarbamol, rosuvastatin, sulfamethoxazole, and temazepam) in bluegill sunfish (Lepomis macrochirus) exposed to environmentally relevant concentrations (1000–4000 ng L–1) in a flow-through exposure system. Temazepam and methocarbamol were consistently detected in bluegill biological samples with the highest concentrations in bile of 4, 940, and 180 ng g–1, respectively, while sulfamethoxazole, diclofenac, and rosuvastatin were only infrequently detected. Over 30-day exposures, the relative magnitude of mean concentrations of temazepam and methocarbamol in biological samples generally followed the order: bile ≫ gut > liver and brain > muscle, plasma, and gill. Ranges of bioconcentration factors (BCFs) in different biological samples were 0.71–3960 and 0.13–48.6 for temazepam and methocarbamol, respectively. Log BCFs were statistically positively correlated to pH adjusted log Kow (that is, log Dow), with the strongest relations for liver and brain (r2 = 0.92 and 0.99, respectively), implying that bioconcentration patterns of ionizable pharmaceuticals depend on molecular status, that is, whether a pharmaceutical is un-ionized or ionized at ambient tissue pH. Methocarbamol and temazepam underwent rapid uptake and elimination in bluegill biological compartments with uptake rate constants (Ku) and elimination rate constants (Ke) at 0.0066–0.0330 h–1 and 0.0075–0.0384 h–1

  9. Kinetic distance and kinetic maps from molecular dynamics simulation

    CERN Document Server

    Noe, Frank

    2015-01-01

    Characterizing macromolecular kinetics from molecular dynamics (MD) simulations requires a distance metric that can distinguish slowly-interconverting states. Here we build upon diffusion map theory and define a kinetic distance for irreducible Markov processes that quantifies how slowly molecular conformations interconvert. The kinetic distance can be computed given a model that approximates the eigenvalues and eigenvectors (reaction coordinates) of the MD Markov operator. Here we employ the time-lagged independent component analysis (TICA). The TICA components can be scaled to provide a kinetic map in which the Euclidean distance corresponds to the kinetic distance. As a result, the question of how many TICA dimensions should be kept in a dimensionality reduction approach becomes obsolete, and one parameter less needs to be specified in the kinetic model construction. We demonstrate the approach using TICA and Markov state model (MSM) analyses for illustrative models, protein conformation dynamics in bovine...

  10. Alternative technical summary report for direct disposition in deep boreholes: Direct disposal of plutonium metal/plutonium dioxide in compound canisters, Version 4.0. Fissile Materials Disposition Program

    Energy Technology Data Exchange (ETDEWEB)

    Wijesinghe, A.M.

    1996-08-23

    This report summarizes and compares the Immobilized and Direct Beep Borehole Disposition Alternatives. The important design concepts, facility features and operational procedures are briefly described, and a discussion of the issues that affect the evaluation of each alternative against the programmatic assessment criteria that have been established for selecting the preferred alternatives for plutonium disposition.

  11. Kinetics of tetrataenite disordering

    Energy Technology Data Exchange (ETDEWEB)

    Dos Santos, E., E-mail: edisanfi@cbpf.br [Centro Brasileiro de Pesquisas Físicas, Rio de Janeiro (Brazil); Gattacceca, J.; Rochette, P. [Centre Européen de Recherche et d’Enseignement des Géosciences de l’Environnement, UM34, CNRS/Aix-Marseille University, Aix-en-Provence (France); Fillion, G. [Laboratoire National des Champs Magnétiques Intenses (LNCMI), CNRS, UJF, 38042 Grenoble (France); Scorzelli, R.B. [Centro Brasileiro de Pesquisas Físicas, Rio de Janeiro (Brazil)

    2015-02-01

    Tetrataenite is a chemically ordered L1{sub 0}-type Fe{sub 50}Ni{sub 50} alloy detected for the first time in 1977 by {sup 57}Fe Mössbauer spectroscopy studies in iron meteorites. The thermal history of meteorites, in particular short thermal events like those associated to hypervelocity impacts, can be constrained by tracing the presence of tetrataenite or its disordering into taenite. The knowledge of the disordering kinetics of tetrataenite, that is associated with changes in its magnetic properties, is still very fragmentary so that the time–temperature history of these meteorites cannot be constrained in details. Furthermore, knowledge of disordering kinetics is important due to potential technological application of tetrataenite as a rare-earth free strong magnet. Thus, this work provides the first time–temperature data for disordering reaction of tetrataenite. We have shown that disordering is not an instantaneous process but is a kinetic limited reaction. It was shown that disordering may take place at any temperature above the order–disorder transition for L{sub 10} superstructure phase (∼320 °C) when the appropriate time-scale is considered. This result means that the apparent Curie point for tetrataenite is not an absolute property in the sense that any estimate of this parameter should be referred to a given time-scale. - Highlights: • The first time–temperature data for tetrataenite disordering reaction is provided. • Previous works does not give a complete picture of tetrataenite disordering. • Apparent Curie temperature of tetrataenite should be referred to a time-scale. • Tetrataenite can be used as a probe to detect thermal/shock events recorded in meteorites.

  12. Kinetics of stress fibers

    Energy Technology Data Exchange (ETDEWEB)

    Stachowiak, Matthew R; O' Shaughnessy, Ben [Department of Chemical Engineering, Columbia University, New York, NY 10027 (United States)], E-mail: bo8@columbia.edu

    2008-02-15

    Stress fibers are contractile cytoskeletal structures, tensile actomyosin bundles which allow sensing and production of force, provide cells with adjustable rigidity and participate in various processes such as wound healing. The stress fiber is possibly the best characterized and most accessible multiprotein cellular contractile machine. Here we develop a quantitative model of the structure and relaxation kinetics of stress fibers. The principal experimentally known features are incorporated. The fiber has a periodic sarcomeric structure similar to muscle fibers with myosin motor proteins exerting contractile force by pulling on actin filaments. In addition the fiber contains the giant spring-like protein titin. Actin is continuously renewed by exchange with the cytosol leading to a turnover time of several minutes. In order that steady state be possible, turnover must be regulated. Our model invokes simple turnover and regulation mechanisms: actin association and dissociation occur at filament ends, while actin filament overlap above a certain threshold in the myosin-containing regions augments depolymerization rates. We use the model to study stress fiber relaxation kinetics after stimulation, as observed in a recent experimental study where some fiber regions were contractile and others expansive. We find that two distinct episodes ensue after stimulation: the turnover-overlap system relaxes rapidly in seconds, followed by the slow relaxation of sarcomere lengths in minutes. For parameter values as they have been characterized experimentally, we find the long time relaxation of sarcomere length is set by the rate at which actin filaments can grow or shrink in response to the forces exerted by the elastic and contractile elements. Consequently, the stress fiber relaxation time scales inversely with both titin spring constant and the intrinsic actin turnover rate. The model's predicted sarcomere velocities and contraction-expansion kinetics are in good

  13. Comparison research on stakeholders analysis of disposition of medical dispute between China and abroad

    Directory of Open Access Journals (Sweden)

    Qin Chen

    2015-01-01

    Full Text Available Objective: We learn about the methods, process, effects of each stakeholder and the principles of the disposition of medical dispute home and abroad through stakeholder analysis. Methods: We investigate the methods, process and the principles of the disposition of medical dispute home and abroad by literature retrieval, key informant interview and depth interview. Results: The stakeholders of medical disputes mainly include patients and families, medical staff and hospitals, pharmaceutical companies, governments, laws, non-government organizations and media. They play different roles in medical disputes and have different effects. Over all, patients and families, medical staff and hospitals have the greatest effect and then laws, media, government, non-government organizations and pharmaceutical companies. Conclusion: Different stakeholders affect the disposition of medical disputes differently. It is crucial to establish harmonious relationship between patients and doctors and to build harmonious society by untangling the responsibility between all the stakeholders and dispose medical disputes quickly and effectively.

  14. The influence of dispositional mindfulness on safety behaviors: a dual process perspective.

    Science.gov (United States)

    Zhang, Jingyu; Wu, Changxu

    2014-09-01

    Based on the dual process model of human cognition, this study investigated the influence of dispositional mindfulness on operators' safety behaviors and its boundary conditions. In a sample of 212 nuclear power plant control room operators, it was found that both safety compliance and safety participation behaviors were positively influenced by dispositional mindfulness as measured by the 14-item Freiburg Mindfulness Inventory. This effect was still positive after controlling for age, intelligence, work experience and conscientiousness. Moreover, two boundary conditions were identified: the impact of dispositional mindfulness of safety behaviors was stronger among operators who were either more experienced or more intelligent. Theoretically, the framework we used to understand the benefit of mindfulness on safety behaviors has been proved to be useful. Practically, it provides a new and valid criterion that could be used in operators' selection and training program to improve organizational safety. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Non-proliferation, safeguards, and security for the fissile materials disposition program immobilization alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, R.A.; Jaeger, C.D.; Tolk, K.M. [Sandia National Labs., Albuquerque, NM (United States); Moore, L.R. [Lawrence Livermore National Lab., CA (United States)

    1996-05-01

    The Department of Energy is analyzing long-term storage and disposition alternatives for surplus weapons-usable fissile materials. A number of different disposition alternatives are being considered. These include facilities for storage, conversion and stabilization of fissile materials, immobilization in glass or ceramic material, fabrication of fissile material into mixed oxide (MOX) fuel for reactors, use of reactor based technologies to convert material into spent fuel, and disposal of fissile material using geologic alternatives. This paper will focus on how the objectives of reducing security and proliferation risks are being considered, and the possible facility impacts. Some of the areas discussed in this paper include: (1) domestic and international safeguards requirements, (2) non-proliferation criteria and measures, (3) the threats, and (4) potential proliferation, safeguards, and security issues and impacts on the facilities. Issues applicable to all of the possible disposition alternatives will be discussed in this paper. However, particular attention is given to the plutonium immobilization alternatives.

  16. Dispositional and comparative optimism interact to predict avoidance of a looming health threat.

    Science.gov (United States)

    Fowler, Stephanie L; Geers, Andrew L

    2015-01-01

    Research indicates that when confronted with a health threat, individuals high in both dispositional and comparative optimism employ a more avoidant style of coping than individuals high in dispositional but low in comparative optimism. We examined the hypothesis that threat distance moderates this interactive optimism association. In two studies, participants were randomly assigned to a looming or distant threat condition. Study 1 revealed that in the looming threat condition, participants high in both forms of optimism were more likely to minimise the threat and less inclined to seek additional health information relative to participants high in dispositional but low in comparative optimism. In Study 2, the same interaction pattern emerged on a measure of psychological abstraction suggesting these variables combine to alter broad information processing strategies. Implications for considering multiple forms of optimism when delivering health status information are discussed.

  17. Relationships Among Dispositional Mindfulness, Distress Tolerance, and Women's Dating Violence Perpetration: A Path Analysis.

    Science.gov (United States)

    Brem, Meagan J; Khaddouma, Alexander; Elmquist, Joanna; Florimbio, Autumn Rae; Shorey, Ryan C; Stuart, Gregory L

    2016-08-24

    Scant research examined mechanisms underlying the relationship between dispositional mindfulness and dating violence (DV) perpetration. Using a cross-sectional design with 203 college women, we examined whether distress tolerance mediated the relationship between dispositional mindfulness and DV perpetration (i.e., psychological aggression and physical assault). Path analyses results revealed indirect effects of mindfulness facets nonjudging of inner experiences and nonreactivity to inner experiences on both psychological aggression and physical assault through distress tolerance. Mindfulness facets observing, describing, and acting with awareness were not linked to DV perpetration through distress tolerance. Results suggest that women who allow internal experiences to come and go without assigning criticism or avoidance are better able to tolerate transient distress and less likely to abuse a dating partner. Future research may examine distress tolerance and dispositional mindfulness facets as potential intervention targets for women who abuse dating partners. © The Author(s) 2016.

  18. Exploring the Relations of Inquiry-Based Teaching to Science Achievement and Dispositions in 54 Countries

    Science.gov (United States)

    Cairns, Dean; Areepattamannil, Shaljan

    2017-06-01

    This study, drawing on data from the third cycle of the Program for International Student Assessment (PISA) and employing three-level hierarchical linear modeling (HLM) as an analytic strategy, examined the relations of inquiry-based science teaching to science achievement and dispositions toward science among 170,474 15-year-old students from 4780 schools in 54 countries across the globe. The results of the HLM analyses, after accounting for student-, school-, and country-level demographic characteristics and students' dispositions toward science, revealed that inquiry-based science teaching was significantly negatively related to science achievement. In contrast, inquiry-based science teaching was significantly positively associated with dispositions toward science, such as interest in and enjoyment of science learning, instrumental and future-oriented science motivation, and science self-concept and self-efficacy. Implications of the findings for policy and practice are discussed.

  19. Anxiety, Dispositional Mindfulness, and Sexual Desire in Men Consulting in Clinical Sexology: A Mediational Model.

    Science.gov (United States)

    Déziel, Julie; Godbout, Natacha; Hébert, Martine

    2017-12-27

    This study aimed to examine dispositional mindfulness as a mediator of the relationship between anxiety and sexual desire in men consulting in clinical sexology. A sample of 105 adult men seeking sex therapy completed measures of dispositional mindfulness, anxiety, and sexual desire. Close to a third (28.7%) of participants reported low sexual desire as their main reason to consult in sex therapy. Path analysis confirmed a mediation model and revealed that the association between anxiety and lower sexual desire was fully mediated by dispositional mindfulness. These findings suggest that mindfulness-based interventions may be a relevant component to integrate in the treatment of men who present anxiety symptoms and low sexual desire.

  20. Chemical kinetics modeling

    Energy Technology Data Exchange (ETDEWEB)

    Westbrook, C.K.; Pitz, W.J. [Lawrence Livermore National Laboratory, CA (United States)

    1993-12-01

    This project emphasizes numerical modeling of chemical kinetics of combustion, including applications in both practical combustion systems and in controlled laboratory experiments. Elementary reaction rate parameters are combined into mechanisms which then describe the overall reaction of the fuels being studied. Detailed sensitivity analyses are used to identify those reaction rates and product species distributions to which the results are most sensitive and therefore warrant the greatest attention from other experimental and theoretical research programs. Experimental data from a variety of environments are combined together to validate the reaction mechanisms, including results from laminar flames, shock tubes, flow systems, detonations, and even internal combustion engines.

  1. Influence of pharmacogenetics on drug disposition and response.

    Science.gov (United States)

    Eichelbaum, M; Evert, B

    1996-01-01

    1. Pharmacogenetics deals with clinically significant hereditary variations in the response to drugs due to altered drug disposition and abnormal action in affected persons. In general, two types of pharmacogenetic conditions can be differentiated. Genetic conditions transmitted as a single factor altering the way drugs act on the body (altered drug action) or genetic conditions transmitted as single factors altering the way the body acts on drugs (altered drug metabolism). These pharmacogenetic conditions can occur either as rare defects or as polymorphisms. 2. Glucose-6-phosphate dehydrogenase deficiency (G6PD) is the most common inherited enzymopathy affecting approximately 400 million people. The main clinical complication associated with G6PD deficiency is haemolysis after ingestion of oxidant drugs (anti-malarials, sulfonamides, analgesics, nitrofurans) and consumption of fava beans. 3. The activity of drug metabolizing enzymes is a major determinant of both the intensity and duration of drug action. The discovery of genetic polymorphisms of drug metabolizing enzymes (e.g. N-acetyltransferase 2 (NAT 2) and cytochrome P450 enzymes CYP2D6 and CYP2C19) has provided an explanation as to why some patients do not obtain the expected drug effects or show exaggerated drug response and serious toxicity after taking the standard and safe dose of a drug. These polymorphisms are expressed in two phenotypes in the population, the extensive (EM) and poor metabolizer (PM). The prevalence of PM is different among different populations. The gene coding for CYP2D6 is highly polymorphic and several mutations have been identified in PM, which all lead to the absence of functional CYP2D6. Poor metabolizers of CYP2D6 and CYP2C19 quite frequently experience exaggerated drug response and side effects when they receive standard doses. If a metabolite is the active therapeutic moiety, PM show no therapeutic response, as demonstrated for the analgesic effect of codeine mediated by its

  2. A Review on Learning Styles and Critically Thinking Disposition of Pre-Service Science Teachers in Terms of Miscellaneous Variables

    Science.gov (United States)

    Yenice, Nilgun

    2012-01-01

    The present study was carried out in order to review learning styles and critical thinking disposition of pre-service science teachers in terms of sex, grade and age, and to address the relationship between their learning styles and critical thinking disposition. It used Kolb's Inventory of Learning Styles and California Scale of Critical Thinking…

  3. 8 CFR 316.11 - Attachment to the Constitution; favorable disposition towards the good order and happiness.

    Science.gov (United States)

    2010-01-01

    ... disposition towards the good order and happiness. 316.11 Section 316.11 Aliens and Nationality DEPARTMENT OF... the Constitution; favorable disposition towards the good order and happiness. (a) General. An... favorably disposed toward the good order and happiness of the United States. Attachment implies a depth of...

  4. Bedside Teaching on Time to Disposition Improves Length of Stay for Critically-ill Emergency Departments Patients

    Directory of Open Access Journals (Sweden)

    Ali Pourmand, MD

    2013-03-01

    Full Text Available Introduction: We tested the effect of a brief disposition process intervention on residents’ time todisposition and emergency department (ED length of stay (LOS in high acuity ED patients.Methods: This was a quasi-experimental study design in a single teaching hospital where ED residentsare responsible for administrative bed requests for patients. Enrollment was performed for interventionand control groups on an even-odd day schedule. Inclusion criteria were ED patients triaged asEmergency Severity Index (ESI 1 and 2. In the intervention group, the attending physician prompted theresident to make the disposition immediately after the evaluation of resuscitation patients. In the controlgroup, the attending physicians did not intervene in the disposition process unless more than 2 hourspassed without a disposition. Main outcomes were time to disposition and total ED LOS.Results: A total of 104 patients were enrolled; 53 (51% in the intervention group and 51 (49% inthe control group. After controlling for ESI and resident training year, mean disposition time wassignificantly shorter in the intervention group by 41.4 minutes (95% CI: 32.6-50.1. LOS was alsoshorter in the intervention group by 93.3 minutes (95% CI: 41.9-144.6.Conclusion: Prompting residents to enter administrative disposition orders in high acuity patientsis associated with significant reduction in both time to disposition and ED LOS.

  5. Engaging in Work Even When It Is Meaningless: Positive Affective Disposition and Meaningful Work Interact in Relation to Work Engagement

    Science.gov (United States)

    Steger, Michael F.; Littman-Ovadia, Hadassah; Miller, Michal; Menger, Lauren; Rothmann, Sebastiaan

    2013-01-01

    The central aim of the present study was to assess the predictive value of affective disposition and meaningful work on employee engagement. Specifically, it was proposed that meaningful work moderates the relationship between affective disposition and engagement. Questionnaires were completed by 252 white-collar employees, working in a variety of…

  6. Prediction of drug disposition on the basis of its chemical structure.

    Science.gov (United States)

    Stepensky, David

    2013-06-01

    The chemical structure of any drug determines its pharmacokinetics and pharmacodynamics. Detailed understanding of relationships between the drug chemical structure and individual disposition pathways (i.e., distribution and elimination) is required for efficient use of existing drugs and effective development of new drugs. Different approaches have been developed for this purpose, ranging from statistics-based quantitative structure-property (or structure-pharmacokinetic) relationships (QSPR) analysis to physiologically based pharmacokinetic (PBPK) models. This review critically analyzes currently available approaches for analysis and prediction of drug disposition on the basis of chemical structure. Models that can be used to predict different aspects of disposition are presented, including: (a) value of the individual pharmacokinetic parameter (e.g., clearance or volume of distribution), (b) efficiency of the specific disposition pathway (e.g., biliary drug excretion or cytochrome P450 3A4 metabolism), (c) accumulation in a specific organ or tissue (e.g., permeability of the placenta or accumulation in the brain), and (d) the whole-body disposition in the individual patients. Examples of presented pharmacological agents include "classical" low-molecular-weight compounds, biopharmaceuticals, and drugs encapsulated in specialized drug-delivery systems. The clinical efficiency of agents from all these groups can be suboptimal, because of inefficient permeability of the drug to the site of action and/or excessive accumulation in other organs and tissues. Therefore, robust and reliable approaches for chemical structure-based prediction of drug disposition are required to overcome these limitations. PBPK models are increasingly being used for prediction of drug disposition. These models can reflect the complex interplay of factors that determine drug disposition in a mechanistically correct fashion and can be combined with other approaches, for example QSPR

  7. An integrated model of feedback-seeking behavior: disposition, context, and cognition.

    Science.gov (United States)

    VandeWalle, D; Ganesan, S; Challagalla, G N; Brown, S P

    2000-12-01

    This study replicates, integrates, and extends prior research on the dispositional, contextual, and cognitive antecedents of feedback-seeking behavior. Regression analysis was used to analyze data collected from a sample of salespeople (N = 310) from 2 Fortune 500 companies. The study hypotheses were supported with the following results. First, the individual disposition of learning goal orientation and the contextual factors of leader consideration and leader initiation of structure influenced cognitions about the perceived cost and value of feedback seeking. Second, the strength of the relationship of learning goal orientation with the cost and value perceptions was moderated by the leadership style of the supervisor.

  8. Association between Cerebral Performance Category, Modified Rankin Scale, and discharge disposition after cardiac arrest.

    Science.gov (United States)

    Rittenberger, Jon C; Raina, Ketki; Holm, Margo B; Kim, Young Joo; Callaway, Clifton W

    2011-08-01

    Cerebral Performance Category (CPC), Modified Rankin Scale (mRS) and discharge disposition are commonly used to determine outcomes following cardiac arrest. This study tested the association between these outcome measures. Retrospective chart review of subjects who survived to hospital discharge between 1/1/2006 and 12/31/2009 was conducted. Charts were reviewed for outcomes (CPC, mRS, and discharge disposition). Discharge disposition was classified in 6 categories: home with no services, home with home healthcare, acute rehabilitation facility, skilled nursing facility, long term acute care facility, and hospice. Intra-and inter-rater reliabilities were calculated for outcome measures. Rates of "good outcome" (defined as a CPC of 1-2, mRS of 0-3, or discharge disposition to home or acute rehabilitation facility) were also determined. Kendall's tau correlation coefficients explored relationships among measures. A total of 211 charts were reviewed. Mean age was 60 years (SD 16), the majority (75%) were white males, in- and out-of hospital cardiac arrests were equally prevalent, and ventricular dysrhythmia was most common (N=109, 52%). Half of the subjects were comatose following resuscitation and 75 (35%) received therapeutic hypothermia. Inter-rater percentage agreement for CPC and mRS abstraction was 95.24% (kappa 0.89, pdefinition, 47 subjects (22%) using the mRS definition, and 129 subjects (61%) subjects using discharge disposition definition. There was fair relationship between the CPC and mRS (tau 0.43) and poor relationships between CPC and discharge disposition (tau 0.23) and between mRS and discharge disposition (tau 0.25). Determination of the CPC, mRS and discharge disposition at hospital discharge is reliable from chart review. These instruments provide widely differing estimates of "good outcome". Agreement between these measures ranges from poor to fair. A more nuanced outcome measure designed for the post-cardiac arrest population is needed

  9. Predictors of academic achievement in adolescents with dispositions to resilience and non-resilience

    Directory of Open Access Journals (Sweden)

    José Gaxiola Romero

    2012-06-01

    Full Text Available There are risk factors influencing academic achievement in high school adolescents that can be contextual and individual. Resilience is the ability of individuals to cope with challenging life experiences. The study aimed to prove an hypothetic model of structural equations in two groups of high school students, a dispositional resilience group and a non-dispositional resilience group, to assess the effects of contextual variables, goals and self-regulation on academic achievement. Results show differences in the variables that explain academic achievement in both groups.

  10. ANATOMICAL DISPOSITION OF CARPAL BONES OF GOLDEN RETRIEVER DOG BY X-RAY EXPOSURE

    Directory of Open Access Journals (Sweden)

    R. Mandal

    2012-07-01

    Full Text Available The present study was conducted to know the general disposition of bones in carpal region of experimental dogs by X-ray study with an objective that the findings will facilitate to have an in-depth knowledge about the proper positioning of the carpal bones for surgical management of fractures and different types of bone deformities in dogs. In the present study, the anatomical disposition and arrangement pattern of carpal bones playing a pivotal role in providing the structural conformity in the limbs of Golden Retriever dog has been thoroughly confirmed by Xray exposure.

  11. Arousability and Dispositional optimism in cyclists with a disability in the context of substance abuse

    Directory of Open Access Journals (Sweden)

    Alena Nosková

    2013-01-01

    Full Text Available The article is focuses at aspects of resistance to psychical stress in cyclists with a disability in the context of substance abuse stimulant effect. The first part includes knowledge about cycling of handicapped and the effect of stimulants at the sports achievement. The article also describes selected constructs of resistance to the psychical stress, like dispositional optimism. The empirical part includes descriptive data from respondents from sports environment. The data on the level of arousability and dispositional optimism are interpreted in the context of substance use by respondents to effect sports achievement. The data are compared with the data of cyclists without handicap.

  12. Kinetics of coal pyrolysis

    Energy Technology Data Exchange (ETDEWEB)

    Seery, D.J.; Freihaut, J.D.; Proscia, W.M. (United Technologies Research Center, East Hartford, CT (USA)); Howard, J.B.; Peters, W.; Hsu, J.; Hajaligol, M.; Sarofim, A. (Massachusetts Inst. of Tech., Cambridge, MA (USA)); Jenkins, R.; Mallin, J.; Espindola-Merin, B. (Pennsylvania State Univ., University Park, PA (USA)); Essenhigh, R.; Misra, M.K. (Ohio State Univ., Columbus, OH (USA))

    1989-07-01

    This report contains results of a coordinated, multi-laboratory investigation of coal devolatilization. Data is reported pertaining to the devolatilization for bituminous coals over three orders of magnitude in apparent heating rate (100 to 100,000 + {degree}C/sec), over two orders of magnitude in particle size (20 to 700 microns), final particle temperatures from 400 to 1600{degree}C, heat transfer modes ranging from convection to radiative, ambient pressure ranging from near vacuum to one atmosphere pressure. The heat transfer characteristics of the reactors are reported in detail. It is assumed the experimental results are to form the basis of a devolatilization data base. Empirical rate expressions are developed for each phase of devolatilization which, when coupled to an awareness of the heat transfer rate potential of a particular devolatilization reactor, indicate the kinetics emphasized by a particular system reactor plus coal sample. The analysis indicates the particular phase of devolatilization that will be emphasized by a particular reactor type and, thereby, the kinetic expressions appropriate to that devolatilization system. Engineering rate expressions are developed from the empirical rate expressions in the context of a fundamental understanding of coal devolatilization developed in the course of the investigation. 164 refs., 223 figs., 44 tabs.

  13. Chemical kinetics of gas reactions

    CERN Document Server

    Kondrat'Ev, V N

    2013-01-01

    Chemical Kinetics of Gas Reactions explores the advances in gas kinetics and thermal, photochemical, electrical discharge, and radiation chemical reactions. This book is composed of 10 chapters, and begins with the presentation of general kinetic rules for simple and complex chemical reactions. The next chapters deal with the experimental methods for evaluating chemical reaction mechanisms and some theories of elementary chemical processes. These topics are followed by discussions on certain class of chemical reactions, including unimolecular, bimolecular, and termolecular reactions. The rema

  14. Adsorption analysis equilibria and kinetics

    CERN Document Server

    Do, Duong D

    1998-01-01

    This book covers topics of equilibria and kinetics of adsorption in porous media. Fundamental equilibria and kinetics are dealt with for homogeneous as well as heterogeneous particles. Five chapters of the book deal with equilibria and eight chapters deal with kinetics. Single component as well as multicomponent systems are discussed. In kinetics analysis, we deal with the various mass transport processes and their interactions inside a porous particle. Conventional approaches as well as the new approach using Maxwell-Stefan equations are presented. Various methods to measure diffusivity, such

  15. Idiosyncratic reality claims, relaxation dispositions, and ABC relaxation theory: happiness, literal christianity, miraculous powers, metaphysics, and the paranormal.

    Science.gov (United States)

    Smith, Jonathan C; Karmin, Aaron D

    2002-12-01

    This study examined idiosyncratic reality claims, that is, irrational or paranormal beliefs often claimed to enhance relaxation and happiness and reduce stress. The Smith Idiosyncratic Reality Claims Inventory and the Smith Relaxation Dispositions Inventory (which measures relaxation and stress dispositions, or enduring states of mind frequently associated with relaxation or stress) were given to 310 junior college student volunteers. Principal components factor analysis with varimax rotation identified five idiosyncratic reality claim factors: belief in Literal Christianity; Magic; Space Aliens: After Death experiences; and Miraculous Powers of Meditation, Prayer, and Belief. No factor correlated with increased relaxation dispositions Peace, Energy, or Joy, or reduced dispositional somatic stress, worry, or negative emotion on the Smith Relaxation Dispositions Inventory. It was concluded that idiosyncratic reality claims may not be associated with reported relaxation, happiness, or stress. In contrast, previous research strongly supported self-affirming beliefs with few paranormal assumptions display such an association.

  16. An Investigation on the Impact of the Socio-Psychological Effects of Teacher Disposition on the Academic Performance of Students in a Diversely Populated Elementary School

    Science.gov (United States)

    Osler, James Edward; Russell, Stacy

    2013-01-01

    The purpose of this research was to examine how teacher disposition affects student academic performance through the validity and reliability of a quantitative inventory instrument: The Teacher Dispositions Index [TDI] that measures the dispositions of effective teachers specified by the Interstate New Teacher Assessment and Support Consortium.

  17. Kinetics of Social Contagion

    Science.gov (United States)

    Ruan, Zhongyuan; Iñiguez, Gerardo; Karsai, Márton; Kertész, János

    2015-11-01

    Diffusion of information, behavioral patterns or innovations follows diverse pathways depending on a number of conditions, including the structure of the underlying social network, the sensitivity to peer pressure and the influence of media. Here we study analytically and by simulations a general model that incorporates threshold mechanism capturing sensitivity to peer pressure, the effect of "immune" nodes who never adopt, and a perpetual flow of external information. While any constant, nonzero rate of dynamically introduced spontaneous adopters leads to global spreading, the kinetics by which the asymptotic state is approached shows rich behavior. In particular, we find that, as a function of the immune node density, there is a transition from fast to slow spreading governed by entirely different mechanisms. This transition happens below the percolation threshold of network fragmentation, and has its origin in the competition between cascading behavior induced by adopters and blocking due to immune nodes. This change is accompanied by a percolation transition of the induced clusters.

  18. The temperature hydration kinetics

    Directory of Open Access Journals (Sweden)

    Mircea Oroian

    2017-07-01

    Full Text Available The aim of this study is to evaluate the hydration kinetics of lentil seeds (Lens culinaris in water at different temperatures (25, 32.5, 40, 55, 70 and 80 °C for assessing the adequacy of models for describing the absorption phenomena during soaking. The diffusion coefficient values were calculated using Fick’s model for spherical and hemispherical geometries and the values were in the range of 10−6 m2/s. The experimental data were fitted to Peleg, Sigmoidal, Weibull and Exponential models. The models adequacy was determined using regression coefficients (R2, root mean square error (RMSE and reduced chi-square (χ2. The Peleg model is the suitable one for predicting the experimental data. Temperature had a positive and significant effect on the water absorption capacities and absorption was an endothermic process.

  19. Kinetics of Social Contagion

    CERN Document Server

    Ruan, Zhongyuan; Karsai, Marton; Kertesz, Janos

    2015-01-01

    Diffusion of information, behavioural patterns or innovations follows diverse pathways depending on a number of conditions, including the structure of the underlying social network, the sensitivity to peer pressure and the influence of media. Here we study analytically and by simulations a general model that incorporates threshold mechanism capturing sensitivity to peer pressure, the effect of `immune' nodes who never adopt, and a perpetual flow of external information. While any constant, non-zero rate of dynamically-introduced innovators leads to global spreading, the kinetics by which the asymptotic state is approached show rich behaviour. In particular we find that, as a function of the density of immune nodes, there is a transition from fast to slow spreading governed by entirely different mechanisms. This transition happens below the percolation threshold of fragmentation of the network, and has its origin in the competition between cascading behaviour induced by innovators and blocking of adoption due ...

  20. Photoisomerization kinetics of trifloxystrobin.

    Science.gov (United States)

    Banerjee, Kaushik; Ligon, Axel Patrick; Spiteller, Michael

    2005-08-01

    The photoisomerization kinetics of trifloxystrobin (TFS) in acetone under artificial sunlight is reported. HPLC analysis showed the TFS, a strobilurine fungicide of EE conformation, was converted into an equilibrium mixture of four isomers after illumination for 7 h. The isomers were identified as EZ, EE, ZZ, and ZE and were separated in the crystalline form by preparative HPLC and characterized by use of a variety of spectroscopic techniques. The quantum yield and reaction constants for the isomerization reactions were determined. The detailed spectral features of the individual isomers measured by UV, IR, Raman, NMR and mass spectroscopy are presented and compared. The spectra of the isomers were found to be very characteristic, with good analytical significance.

  1. KINETIC SPECTROPHOTOMETRIC DETERMINATION OF SOME ...

    African Journals Online (AJOL)

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    ABSTRACT. A simple and sensitive kinetic spectrophotometric method was developed for the determination of some fluoroquinolonea antibiotics; gemifloxacin mesylate, moxifloxacin hydrochloride and gatifloxacin in bulk and in pharmaceutical preparations. The method is based upon a kinetic investigation of the oxidation ...

  2. Dimensional enhancement of kinetic energies

    DEFF Research Database (Denmark)

    Schleich, W.P.; Dahl, Jens Peder

    2002-01-01

    Simple thermodynamics considers kinetic energy to be an extensive variable which is proportional to the number N of particles. We present a quantum state of N noninteracting particles for which the kinetic energy increases quadratically with N. This enhancement effect is tied to the quantum centr...

  3. 75 FR 12377 - Native American Graves Protection and Repatriation Act Regulations-Disposition of Culturally...

    Science.gov (United States)

    2010-03-15

    ... objects and objects of cultural patrimony. Among other things, the Act: --Established the Native American..., disposition of human remains, funerary objects, sacred objects, or objects of cultural patrimony removed from... the repatriation of human remains, funerary objects, sacred objects, or objects of cultural patrimony...

  4. 19 CFR 144.7 - Disposition of merchandise after expiration of warehousing period.

    Science.gov (United States)

    2010-04-01

    ... warehousing period. 144.7 Section 144.7 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF... General Provisions § 144.7 Disposition of merchandise after expiration of warehousing period. Merchandise remaining in a bonded warehouse after the expiration of the warehousing period shall be disposed of in...

  5. The Relationship between Writing Anxiety and Writing Disposition among Secondary School Students

    Science.gov (United States)

    Cocuk, Halil Erdem; Yanpar Yelken, Tugba; Ozer, Omer

    2016-01-01

    Problem Statement: Writing is important in secondary schools because it underpins the performance of students in most examinations. Writing disposition, which specifically deals with the aspects of students' attitudes toward writing, has also been studied by some researchers. Purpose of the Study: This study reports on the result of a study on the…

  6. How Do School Librarians Perceive Dispositions for Learning and Social Responsibility?

    Science.gov (United States)

    Arnone, Marilyn

    2010-01-01

    This article discusses the implication of the study involving school librarians regarding how they perceive dispositions for learning and social responsibility. It also presents descriptive results of the most common areas discussed by participants, and provides anecdotal data from the transcripts and some subjective impressions of the researcher.…

  7. 9 CFR 354.141 - Issuance and disposition of rabbits inspection certificates.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Issuance and disposition of rabbits inspection certificates. 354.141 Section 354.141 Animals and Animal Products FOOD SAFETY AND INSPECTION... certificates. (a) Upon the request of an interested party, any inspector is authorized to issue a rabbit...

  8. An Analysis of Mathematics Teacher Candidates' Critical Thinking Dispositions and Their Logical Thinking Skills

    Science.gov (United States)

    Incikabi, Lutfi; Tuna, Abdulkadir; Biber, Abdullah Cagri

    2013-01-01

    This study aimed to investigate the existence of the relationship between mathematics teacher candidates' critical thinking skills and their logical thinking dispositions in terms of the variables of grade level in college, high school type, and gender. The current study utilized relational survey model and included a total of 99 mathematics…

  9. Fostering Elementary Students' Mathematics Disposition through Music-Mathematics Integrated Lessons

    Science.gov (United States)

    An, Song A.; Tillman, Daniel A.; Boren, Rachel; Wang, Junjun

    2014-01-01

    Two classes of third grade students (n = 56) from an elementary school located on the western coast of the United States participated in this research study. A pretest-posttest control group design was utilized to examine changes between two groups of participating students' in mathematics achievement and dispositions, including beliefs about…

  10. Exploration to Identify Professional Dispositions of School Librarians: A Delphi Study

    Science.gov (United States)

    Bush, Gail; Jones, Jami L.

    2010-01-01

    This article reports the findings of an exploratory study to identify professional dispositions of school librarians. The authors employed the Delphi method, a qualitative research method that emphasizes expert knowledge and consensus within a particular field. The Delphi panel consisted of members of the editorial boards of nationally recognized…

  11. 7 CFR 767.52 - Disposition of personal property from real estate inventory property.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Disposition of personal property from real estate..., personal property has been left on the real estate inventory property, the Agency will notify the former real estate owner and any known lienholders that the Agency will dispose of the personal property...

  12. Dispositions Supporting Elementary Interns in the Teaching of Reform-Based Science Materials

    Science.gov (United States)

    Eick, Charles J.; Stewart, Bethany

    2010-01-01

    Dispositions supporting the teaching of science as structured inquiry by four elementary candidates are presented. Candidates were studied during student teaching based on their positive attitudes toward teaching science with reform-based materials in their methods course. Personal learning histories informed their attitudes, values, and beliefs…

  13. 9 CFR 329.7 - Procedure for seizure, condemnation, and disposition.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Procedure for seizure, condemnation... AND VOLUNTARY INSPECTION AND CERTIFICATION DETENTION; SEIZURE AND CONDEMNATION; CRIMINAL OFFENSES § 329.7 Procedure for seizure, condemnation, and disposition. Any article or livestock subject to...

  14. A Mixed Methods Analysis of Students' Understanding of Slope and Derivative Concepts and Students' Mathematical Dispositions

    Science.gov (United States)

    Patel, Rita Manubhai

    2013-01-01

    This dissertation examined understanding of slope and derivative concepts and mathematical dispositions of first-semester college calculus students, who are recent high school graduates, transitioning to university mathematics. The present investigation extends existing research in the following ways. First, based on this investigation, the…

  15. Problematic Internet Usage: Personality Traits, Gender, Age and Effect of Dispositional Hope Level

    Science.gov (United States)

    Cetin Gudunz, Hicran; Eksioglu, Subhan; Tarhan, Sinem

    2017-01-01

    Purpose: The aim of this study is to examine the effect of personality traits, gender, age and effects of dispositional hope level in problematic internet usage of university students. Research Methods: This paper is an example of a descriptive study, which presents the relationship between problematic internet usage of university students…

  16. Examining a model of dispositional mindfulness, body comparison, and body satisfaction

    NARCIS (Netherlands)

    Dijkstra, Pieternel; Barelds, Dick P. H.

    The present study examined the links between dispositional mindfulness, body comparison, and body satisfaction. It was expected that mindfulness would be associated with less body comparison and more body satisfaction. Two models were tested: one exploring body comparison as a mediator between

  17. Dispositional mindfulness co-varies with smaller amygdala and caudate volumes in community adults.

    Directory of Open Access Journals (Sweden)

    Adrienne A Taren

    Full Text Available Mindfulness, a psychological process reflecting attention and awareness to what is happening in the present moment, has been associated with increased well-being and decreased depression and anxiety in both healthy and patient populations. However, little research has explored underlying neural pathways. Recent work suggests that mindfulness (and mindfulness training interventions may foster neuroplastic changes in cortico-limbic circuits responsible for stress and emotion regulation. Building on this work, we hypothesized that higher levels of dispositional mindfulness would be associated with decreased grey matter volume in the amgydala. In the present study, a self-report measure of dispositional mindfulness and structural MRI images were obtained from 155 healthy community adults. Volumetric analyses showed that higher dispositional mindfulness is associated with decreased grey matter volume in the right amygdala, and exploratory analyses revealed that higher dispositional mindfulness is also associated with decreased grey matter volume in the left caudate. Moreover, secondary analyses indicate that these amygdala and caudate volume associations persist after controlling for relevant demographic and individual difference factors (i.e., age, total grey matter volume, neuroticism, depression. Such volumetric differences may help explain why mindful individuals have reduced stress reactivity, and suggest new candidate structural neurobiological pathways linking mindfulness with mental and physical health outcomes.

  18. Maternal Dispositional Empathy and Electrodermal Reactivity: Interactive Contributions to Maternal Sensitivity with Toddler-Aged Children

    Science.gov (United States)

    Emery, Helen T.; McElwain, Nancy L.; Groh, Ashley M.; Haydon, Katherine C.; Roisman, Glenn I.

    2015-01-01

    The present study investigated maternal dispositional empathy and skin conductance level (SCL) reactivity to infant emotional cues as joint predictors of maternal sensitivity. Sixty-four mother-toddler dyads (31 boys) were observed across a series of interaction tasks during a laboratory visit, and maternal sensitivity was coded from approximately 55 minutes of observation per family. In a second, mother-only laboratory visit, maternal SCL reactivity to infant cues was assessed using a cry-laugh audio paradigm. Mothers reported on their dispositional empathy via a questionnaire. As hypothesized, mothers with greater dispositional empathy exhibited more sensitive behavior at low, but not high, levels of SCL reactivity to infant cues. Analyses examining self-reported emotional reactivity to the cry-laugh audio paradigm yielded a similar finding: dispositional empathy was related to greater sensitivity when mothers reported low, but not high, negative emotional reactivity. Results provide support for Dix’s (1991) affective model of parenting that underscores the combined contribution of the parent’s empathic tendencies and his/her own emotional experience in response to child emotions. Specificity of the Empathy × Reactivity interaction is discussed with respect to the context in which reactivity was assessed (infant cry versus laugh) and the type of sensitivity examined (sensitivity to the child’s distress versus non-distress). PMID:24955589

  19. A Study of Preservice Educators' Dispositions to Change Behavior Management Strategies

    Science.gov (United States)

    Shook, Alison C.

    2012-01-01

    Student behavior problems contribute to poor academic achievement and poor teacher retention. This study investigated preservice teachers' dispositions to implement positive and proactive strategies for managing behavior in the general education elementary urban classroom. The author interviewed 19 preservice teachers in a large urban school…

  20. Transfer and Dispositions in Writing Centers: A Cross-Institutional, Mixed-Methods Study

    Science.gov (United States)

    Bromley, Pam; Northway, Kara; Schonberg, Eliana

    2016-01-01

    Taking a dispositional view of transfer and applying Joanne Lobato's "actor-oriented transfer perspective," we analyze student perceptions of writing center visits at three very different institutions. We find that, as a nonevaluative space where university students can develop metacognitive awareness across disciplines and over time,…

  1. Dispositional Optimism as a Correlate of Decision-Making Styles in Adolescence

    OpenAIRE

    Paola Magnano; Anna Paolillo; Barbara Giacominelli

    2015-01-01

    Despite the numerous psychological areas in which optimism has been studied, including career planning, only a small amount of research has been done to investigate the relationship between optimism and decision-making styles. Consequently, we have investigated the role of dispositional optimism as a correlate of different decision-making styles, in particular, positive for effective styles and negative for ineffective...

  2. The Relationship between Critical Thinking Disposition and Locus of Control in Pre-Service Teachers

    Science.gov (United States)

    Oguz, Aytunga; Sariçam, Hakan

    2016-01-01

    The aim of the current research study was to examine the link between critical thinking dispositions and locus of control in pre-service teachers. The participants of this study were selected via easily accessible sampling technique. The participants consist of 347 pre-service teachers (203 female, 144 male) in Kütahya, Turkey. The Rotter…

  3. Wanting, having, and needing: integrating motive disposition theory and self-determination theory.

    Science.gov (United States)

    Sheldon, Kennon M; Schüler, Julia

    2011-11-01

    Four studies explored the motivational and experiential dynamics of psychological needs, applying both self-determination theory and motive disposition theory. In all 4 studies, motive dispositions toward achievement and affiliation ("wanting" particular experiences) predicted corresponding feelings of competence and relatedness ("having" those experiences). Competence and relatedness in turn predicted well-being, again indicating that these 2 experiences may really be "needed." Illuminating how wanting gets to having, in Studies 2 and 3, participants reported greater self-concordance for motive-congruent goals, which, in longitudinal Study 3, predicted greater attainment of those goals and thus enhanced well-being. Study 4 replicated selected earlier results using an implicit as well as an explicit motive disposition measure. Supporting the presumed universality of competence and relatedness needs, in no studies did motive dispositions moderate the effects of corresponding need-satisfaction on well-being. Discussion focuses on a "sequential process" model of psychological needs that views needs as both motives that instigate and outcomes that reward behavior.

  4. Critical Thinking and Disposition Toward Critical Thinking Among Physical Therapy Students.

    Science.gov (United States)

    Domenech, Manuel A; Watkins, Phillip

    2015-01-01

    Students who enter a physical therapist (PT) entry-level program with weak critical thinking skills may not be prepared to benefit from the educational training program or successfully engage in the future as a competent healthcare provider. Therefore, assessing PT students' entry-level critical thinking skills and/or disposition toward critical thinking may be beneficial to identifying students with poor, fair, or good critical thinking ability as one of the criteria used in the admissions process into a professional program. First-year students (n=71) from the Doctor of Physical Therapy (DPT) program at Texas Tech University Health Sciences Center completed the California Critical Thinking Skills Test (CCTST), the California Critical Thinking Dispositions Inventory (CCTDI), and demographic survey during orientation to the DPT program. Three students were lost from the CCTST (n=68), and none lost from the CCTDI (n=71). Analysis indicated that the majority of students had a positive disposition toward critical thinking, yet the overall CCTST suggested that these students were somewhat below the national average. Also, individuals taking math and science prerequisites at the community-college level tended to have lower overall CCTST scores. The entering DPT class demonstrated moderate or middle range scores in critical thinking and disposition toward critical thinking. This result does not indicate, but might suggest, the potential for learning challenges. Assessing critical thinking skills as part of the admissions process may prove advantageous.

  5. Gender Differences in High School Student Dispositions toward Science, Technology, Engineering, and Mathematics Careers

    Science.gov (United States)

    Christensen, Rhonda; Knezek, Gerald; Tyler-Wood, Tandra

    2015-01-01

    STEM disposition surveys were completed by 364 11th and 12th grade students attending a two-year university-based residential science and mathematics academy during fall 2012. Surveys were completed by the same classes as a post test administration during spring 2013. Major findings were that first year students tended to show a decline in their…

  6. Dispositions and Practices That Promote Teacher-Student Relationships with African-American Male Elementary Students

    Science.gov (United States)

    Yeldell, Karyn Mitchell

    2013-01-01

    This research study was focused on teacher dispositions and practices that create positive teacher-student relationships with African-American elementary male students. Robert Pianta's work on relationships between teachers and students, over the past decade, provided a conceptual framework for this specific study. A review of the literature…

  7. Critical-Thinking Dispositions among Dietetic Interns at the Completion of Their Internship

    Science.gov (United States)

    Schumacher, Julie Raeder

    2014-01-01

    Critical-thinking skills permeate the ability to pass tests such as the Certification Registration Examination for Dietitians (RD Exam) (Dietetic Educators of Practitioners, 2011). The impact of critical thinking on the RD Exam should be evaluated to assist faculty members when developing curriculum-especially as trends in dispositions emerge.…

  8. Cross-Sectional Evaluation of Distance Education Students' Learning Styles and Critical Thinking Dispositions in Turkey

    Science.gov (United States)

    Yüksel, Ismail; Türkses, Ercüment

    2015-01-01

    This study aims to examine distance education students' learning styles and critical thinking dispositions. This cross sectional survey was conducted on 114 Turkish distance education students from various departments in a state university. The data of the study were collected through Grasha-Riechmann Student Learning Style Scale (GRSLSS) and…

  9. Attitude Has a Lot to Do with It: Dispositions of Emerging Teacher Leadership

    Science.gov (United States)

    Hunzicker, Jana

    2013-01-01

    Part of a larger qualitative study to better understand how teachers learn to exercise informal leadership in the schools and districts where they work, this article illustrates dispositions of emerging teacher leadership by identifying and describing three possible teacher leadership prerequisites through lived experience examples. Eight…

  10. 77 FR 44222 - Notice of Availability of the Draft Surplus Plutonium Disposition Supplemental Environmental...

    Science.gov (United States)

    2012-07-27

    ... from surplus plutonium in domestic commercial nuclear power reactors to generate electricity, including... fuel in commercial nuclear reactors used to generate electricity. TVA is a cooperating agency on this... engaged in a program to disposition its surplus, weapons-usable plutonium in an environmentally sound...

  11. The Relationship between Writing Dispositions and Intelligence Domains of Gifted Students

    Science.gov (United States)

    Sengul, Murat

    2015-01-01

    This study investigated the relationship between intelligence profiles of gifted secondary school students and their writing dispositions. The study group comprised of 61 secondary school students in Erzurum Cevat Dursunoglu and Elazig Science and Art Center in Turkey. Data collection tools were Multiple Intelligence Inventory, Writing Disposition…

  12. The Predictive Validity of Critical Thinking Disposition on Middle-Grades Math Achievement

    Science.gov (United States)

    LaVenia, Mark; Pineau, Kristina N.; Lang, Laura B.

    2010-01-01

    This study investigates the predictive validity of students' levels of critical thinking disposition, as measured by the California Measure of Mental Motivation (CM3; Giancarlo, Blohm, & Urdan, 2004) for students' math achievement, as measured by the Mathematics assessment included in the Florida Comprehensive Assessment Test (FCAT). The CM3…

  13. Analysis of Disposition Measures of Consistency with INTASC Principles: Results of an Initial Study

    Science.gov (United States)

    Lang, William Steve

    2005-01-01

    This paper reports the analysis of the results from a pilot effort to create and use a battery of instruments based on INTASC principles indicators of teacher dispositions. The original conception of the battery was designed on the taxonomy of increasing levels of inference. This means that the intent to measure included multiple instruments in…

  14. Dispositional employability and online training purchase. Evidence from employees’ behavior in Spain

    Directory of Open Access Journals (Sweden)

    Joan eTorrent-Sellens

    2016-06-01

    Full Text Available This article explores the relationship between dispositional employability and online training purchase. Through a sample of 883 employees working for enterprises in Spain, and a using principal component analysis and binomial logit probabilistic models, the research revealed two main results. First, it was found that dispositional employability is characterized by five factors: openness to changes at work, career motivation and work resilience, work and career proactivity, optimism and engagement at work, and work identity. Second, the research also found a double causality in the relationship analysis between dispositional employability and online training purchase. However, this causality is not direct. In explaining dispositional employability, certain motivations and types of behavior of employees participating in online training are significant. In particular, greater sensitivity towards career-related personal empowerment, a greater predisposition towards developing new experiences at work, and a greater awareness of the fact that positive job outcomes are related to preparation conscientiousness. In explaining online training purchase, employees who are more motivated and who better identify with their jobs are more likely to pay. Moreover, employees who spend more time on training and have less contact with new trends in their jobs, find it hard to keep calm in difficult situations, and have a greater predisposition towards effort, and preference for novelty, variety and challenges at work are more likely to purchase online training.

  15. Technology Leadership Is Just Good Leadership: Dispositions of Tech Savvy Superintendents

    Science.gov (United States)

    Richardson, Jayson W.; McLeod, Scott; Sauers, Nick

    2015-01-01

    This study describes core dispositions of school district superintendents who have been identified as technology savvy leaders by a prominent educational technology newspaper. The superintendents in this study described how they accomplished their technology initiatives and offered suggestions for other superintendents who aspire to be more…

  16. 37 CFR 251.64 - Disposition of petition; initiation of arbitration proceeding.

    Science.gov (United States)

    2010-07-01

    ...; initiation of arbitration proceeding. 251.64 Section 251.64 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES COPYRIGHT ARBITRATION ROYALTY PANEL RULES OF PROCEDURE Rate Adjustment Proceedings § 251.64 Disposition of petition...

  17. Student profiling in a dispositional learning analytics application using formative assessment

    NARCIS (Netherlands)

    Tempelaar, Dirk; Rienties, Bart; Mittelmeier, Jenna; Nguyen, Quan

    2017-01-01

    How learning disposition data can help us translating learning feedback from a learning analytics application into actionable learning interventions, is the main focus of this empirical study. It extends previous work (Tempelaar, Rienties, & Giesbers, 2015), where the focus was on deriving timely

  18. Comparing Determinants of Perceived and Actual Recycling Skills: The Role of Motivational, Behavioral and Dispositional Factors

    Science.gov (United States)

    Passafaro, Paola; Livi, Stefano

    2017-01-01

    An empirical investigation assessed the role of different factors of motivational, behavioral, and dispositional nature in the prediction of both perceived and actual skills concerning household waste recycling. A structured questionnaire (measuring attitudes, social norms, perceived control, need for cognitive closure, self-reported household…

  19. The Benefits of Dispositional Mindfulness in Physical Health: A Longitudinal Study of Female College Students

    Science.gov (United States)

    Murphy, Megan J.; Mermelstein, Liza C.; Edwards, Katie M.; Gidycz, Christine A.

    2012-01-01

    Objective: This article examines the relationship between dispositional mindfulness, health behaviors (e.g., sleep, eating, and exercise), and physical health. Participants: Participants included 441 college women. Methods: Women completed self-report surveys at the beginning and end of a 10-week academic quarter. The study was conducted over 5…

  20. Dispositional Mindfulness Co-varies with Self-Reported Positive Reappraisal

    OpenAIRE

    Hanley, Adam W.; Garland, Eric L.

    2014-01-01

    Emerging research suggests that mindfulness is associated with positive reappraisal and that mindfulness practice may be a means of encouraging positive reappraisal capacities. These findings, linking mindfulness with the promotion of cognitive coping strategies, challenge traditional Western conceptualizations of mindfulness as non-discursive. This study explored the relationship between dispositional mindfulness and self-reported positive reappraisal across five distinct samples: a general ...

  1. Critical Thinking Disposition and Skills in Dental Students: Development and Relationship to Academic Outcomes.

    Science.gov (United States)

    Whitney, Eli M; Aleksejuniene, Jolanta; Walton, Joanne N

    2016-08-01

    Critical thinking is a key element of complex problem-solving and professional behavior. An ideal critical thinking measurement instrument would be able to accurately predict which dental students are predisposed to and capable of thinking critically and applying such thinking skills to clinical situations. The aims of this study were to describe critical thinking disposition and skills in dental students at the beginning and end of their first year, examine cohort and gender effects, and compare their critical thinking test scores to their first-year grades. Volunteers from three student cohorts at the University of British Columbia were tested using the California Critical Thinking Disposition Inventory and California Critical Thinking Skills instruments at the beginning and end of their first year. Based on the preliminary findings, one cohort was retested at graduation when their final-year grades and clinical advisor rankings were compared to their critical thinking test scores. The results showed that students who entered dental school with higher critical thinking scores tended to complete their first year with higher critical thinking scores, achieve higher grades, and show greater disposition to think critically at the start of the program. Students who demonstrated an ability to think critically and had a disposition to do so at the start of the program were also likely to demonstrate those same attributes at the completion of their training. High critical thinking scores were associated with success in both didactic and clinical settings in dental school.

  2. Analysing the Correlations between Primary School Teachers' Teaching Styles and Their Critical Thinking Disposition

    Science.gov (United States)

    Sen, Özgür

    2018-01-01

    This study aims to analyse the correlations between teaching styles primary school teachers prefer to use and their critical thinking disposition. The research was conducted with the participation of 380 primary school teachers teaching in schools located in Ankara. The study employs relational survey model. In this study "Teaching Styles…

  3. 32 CFR 552.130 - Disposition of confiscated/seized weapons.

    Science.gov (United States)

    2010-07-01

    .... All weapons, ammunition, explosives, or other devices defined in this subpart, that are confiscated... evidence, or other law disposition. When retention for investigation or evidence is no longer required by... under the provisions of AR 195-5, Evidence Procedures. Copies of the AR may be obtained from the...

  4. Identification of Relationships between Emotional Intelligence Skill & Critical Thinking Disposition in Undergraduate Leadership Students

    Science.gov (United States)

    Stedman, Nicole L. P.; Andenoro, Anthony C.

    2007-01-01

    Engaging students emotionally is the key to strengthening their dispositions toward critical thinking. Elder (1997) contends that it is critical thinking which leads us to a rational and reasonable emotional life. The link between thinking and emotions is essential in leadership education. With this in mind, the researchers sought to examine the…

  5. 25 CFR 11.608 - Final decree; disposition of property; maintenance; child support; custody.

    Science.gov (United States)

    2010-04-01

    ... support; custody. 11.608 Section 11.608 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW...; disposition of property; maintenance; child support; custody. (a) A decree of dissolution of marriage or of... bringing the action. (4) Make child custody determinations in accordance with the best interest of the...

  6. Optimization as a Dispositive in the Production of Differences in Denmark Schools

    Science.gov (United States)

    Hamre, Bjørn

    2014-01-01

    The theoretical framework of this paper is inspired by governmentality studies in education. The key concepts are problematization, formatting technologies, and dispositive. The paper begins with an empirical study conducted in Denmark of forty-four files from educational psychologists and articles from journals concerning schools and education.…

  7. 36 CFR 1225.18 - How do agencies request records disposition authority?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false How do agencies request... records disposition authority? (a) Federal agencies submit an SF 115 to NARA to request authority to... basis. (b) SF 115s include only records not covered by the General Records Schedules (GRS) (see part...

  8. When dispositional and role power fit: implications for self-expression and self-other congruence.

    Science.gov (United States)

    Chen, Serena; Langner, Carrie A; Mendoza-Denton, Rodolfo

    2009-03-01

    Integrating and extending the literatures on social power and person-environment fit, 4 studies tested the hypothesis that when people's dispositional beliefs about their capacity to influence others fit their assigned role power, they are more likely to engage in self-expression-that is, behave in line with their states and traits-thereby increasing their likelihood of being perceived by others in a manner congruent with their own self-judgments (i.e., self-other congruence). In Studies 1-3, dispositionally high- and low-power participants were randomly assigned to play a high- or low-power role in an interaction with a confederate. When participants' dispositional and role power fit (vs. conflicted), they reported greater self-expression (Study 1). Furthermore, under dispositional-role power fit conditions, the confederate's ratings of participants' emotional experiences (Study 2) and personality traits (Study 3) were more congruent with participants' self-reported emotions and traits. Study 4's results replicated Study 3's results using an implicit manipulation of power and outside observers' (rather than a confederate's) ratings of participants. Implications for research on power and person perception are discussed.

  9. 76 FR 24042 - Notice of Proposed Information Collection: Comment Request; Disposition of Multifamily Housing...

    Science.gov (United States)

    2011-04-29

    ... of Asset Management, Multifamily Housing, Department of Housing and Urban Development, 451 7th Street..., Disposition of Multifamily Housing Projects by HUD; Purchaser's Compliance With State and Local Housing Laws... codes. This information collection requires potential purchasers of HUD-owned multifamily housing...

  10. 24 CFR 9.152 - Program accessibility: alterations of Property Disposition Program multifamily housing facilities.

    Science.gov (United States)

    2010-04-01

    ... of Property Disposition Program multifamily housing facilities. 9.152 Section 9.152 Housing and Urban... housing facilities. (a) Substantial alteration. If the agency undertakes alterations to a PDP multifamily... in a PDP multifamily housing project shall, to the maximum extent feasible, be made to be readily...

  11. 32 CFR Appendix B to Part 172 - Disposition of Amounts Collected From Successful Bidders

    Science.gov (United States)

    2010-07-01

    ... DEFENSE CONTRACTING DISPOSITION OF PROCEEDS FROM DOD SALES OF SURPLUS PERSONAL PROPERTY Pt. 172, App. B... purchased with funds from trust fund _ X8420, “Surcharge Collections, Sales of Commissary Stores” _ X8420... leased to DoD _ F3875, Budget Clearing Account (Suspense) _ F3875. Upon receipt of the entire amount due...

  12. Dispositional Mindfulness and Depressive Symptomatology: Correlations with Limbic and Self-Referential Neural Activity during Rest

    Science.gov (United States)

    Way, Baldwin M.; Creswell, J. David; Eisenberger, Naomi I.; Lieberman, Matthew D.

    2010-01-01

    To better understand the relationship between mindfulness and depression, we studied normal young adults (n=27) who completed measures of dispositional mindfulness and depressive symptomatology, which were then correlated with: a) Rest: resting neural activity during passive viewing of a fixation cross, relative to a simple goal-directed task (shape-matching); and b) Reactivity: neural reactivity during viewing of negative emotional faces, relative to the same shape-matching task. Dispositional mindfulness was negatively correlated with resting activity in self-referential processing areas, while depressive symptomatology was positively correlated with resting activity in similar areas. In addition, dispositional mindfulness was negatively correlated with resting activity in the amygdala, bilaterally, while depressive symptomatology was positively correlated with activity in the right amygdala. Similarly, when viewing emotional faces, amygdala reactivity was positively correlated with depressive symptomatology and negatively correlated with dispositional mindfulness, an effect that was largely attributable to differences in resting activity. These findings indicate that mindfulness is associated with intrinsic neural activity and that changes in resting amygdala activity could be a potential mechanism by which mindfulness-based depression treatments elicit therapeutic improvement. PMID:20141298

  13. Dispositional Mindfulness Co-Varies with Smaller Amygdala and Caudate Volumes in Community Adults

    Science.gov (United States)

    Taren, Adrienne A.; Creswell, J. David; Gianaros, Peter J.

    2013-01-01

    Mindfulness, a psychological process reflecting attention and awareness to what is happening in the present moment, has been associated with increased well-being and decreased depression and anxiety in both healthy and patient populations. However, little research has explored underlying neural pathways. Recent work suggests that mindfulness (and mindfulness training interventions) may foster neuroplastic changes in cortico-limbic circuits responsible for stress and emotion regulation. Building on this work, we hypothesized that higher levels of dispositional mindfulness would be associated with decreased grey matter volume in the amgydala. In the present study, a self-report measure of dispositional mindfulness and structural MRI images were obtained from 155 healthy community adults. Volumetric analyses showed that higher dispositional mindfulness is associated with decreased grey matter volume in the right amygdala, and exploratory analyses revealed that higher dispositional mindfulness is also associated with decreased grey matter volume in the left caudate. Moreover, secondary analyses indicate that these amygdala and caudate volume associations persist after controlling for relevant demographic and individual difference factors (i.e., age, total grey matter volume, neuroticism, depression). Such volumetric differences may help explain why mindful individuals have reduced stress reactivity, and suggest new candidate structural neurobiological pathways linking mindfulness with mental and physical health outcomes. PMID:23717632

  14. Investigating Lifelong Learning Dispositions of Students Studying English Language and Literature in Terms of Different Variables

    Science.gov (United States)

    Elaldi, Senel

    2015-01-01

    This study aims to determine lifelong learning dispositions of English Language and Literature students in terms of gender, grade levels, and age variables. Descriptive research design was used. The study group consisted of 402 students studying English Language and Literature at Cumhuriyet University in Sivas, Turkey. Research data were collected…

  15. The Relationship between Teachers' Democratic Classroom Management Attitudes and Students' Critical Thinking Dispositions

    Science.gov (United States)

    Turabik, Tugba; Gün, Feyza

    2016-01-01

    This study aimed to investigate the relationship between democratic classroom management attitudes of teachers and critical thinking dispositions of students. The study group consisted of 530 students from public high schools located in Altindag district of the province of Ankara. The data was collected with the use of "Democratic Classroom…

  16. Disposition of [14C]γ-cyclodextrin in germ-free and conventional rats

    NARCIS (Netherlands)

    Bie, A.T.H.J. de; Ommen, B. van; Bär, A.

    1998-01-01

    The absorption, disposition, metabolism, and excretion of 14C-labeled γ-cyclodextrin ([14C]γ-CD) was examined in four separate experiments with Wistar rats. In experiment 1, [14C]γ-CD (25 μCi, 600 mg/kg body wt) was administered intravenously to four male and four female conventional rats. In

  17. Understanding How Service-Learning Impacts the Dispositions of Teach for America Candidates and Their Students

    Science.gov (United States)

    Mitchell, Dymaneke; Karlin, Sy; Price, Todd

    2014-01-01

    This article is based on a study that assessed Teach for America (TFA) candidates' dispositions toward service-learning before and after they developed and implemented a service-learning project with their students. This article may be used to understand the significance of raising alternative certification teacher candidates' community awareness…

  18. Developing Critical-Thinking Dispositions in a Listening/Speaking Class

    Science.gov (United States)

    Ordem, Eser

    2017-01-01

    Studies on critical thinking (CT) in education have been of paramount importance in recent decades to help individuals develop skills such as analyzing, synthesizing, higher-order thinking, and assessing. In line with such studies, this study aims to examine aspects of critical thinking dispositions of Turkish adult learners of English in a…

  19. Examining the Critical Thinking Dispositions and the Problem Solving Skills of Computer Engineering Students

    Science.gov (United States)

    Özyurt, Özcan

    2015-01-01

    Problem solving is an indispensable part of engineering. Improving critical thinking dispositions for solving engineering problems is one of the objectives of engineering education. In this sense, knowing critical thinking and problem solving skills of engineering students is of importance for engineering education. This study aims to determine…

  20. One-to-One Laptop Teacher Education: Does Involvement Affect Candidate Technology Skills and Dispositions?

    Science.gov (United States)

    Donovan, Loretta; Green, Tim; Hansen, Laurie E.

    2012-01-01

    This study compares teacher candidates' initial and changed beliefs, dispositions, and uses of technology in two credential program models: a one-to-one laptop program with ubiquitous technology use and a traditional credential program in which students are expected to have specific technology experiences and requirements in each course (a model…

  1. 30 CFR 220.015 - Pricing of materiel purchases, transfers, and dispositions.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Pricing of materiel purchases, transfers, and... CONTINENTAL SHELF OIL AND GAS LEASES § 220.015 Pricing of materiel purchases, transfers, and dispositions. (a... § 220.011(c)(3). (2) Transferred and disposal materiel. An item of materiel, which is acquired by the...

  2. Results from the Interim Salt Disposition Program Macrobatch 11 Tank 21H Acceptance Samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Bannochie, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-11-13

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of verification of Macrobatch (Salt Batch) 11 for the Interim Salt Disposition Program (ISDP) for processing. This document reports characterization data on the samples of Tank 21H and fulfills the requirements of Deliverable 3 of the Technical Task Request (TTR).

  3. Identifying the Administrative Dispositions Most Preferred by Urban School Leaders and School Leadership Candidates

    Science.gov (United States)

    Pregot, Michael

    2016-01-01

    This research study delves into the newly crafted ISSLC national school leadership standards asking current school leaders and school leadership candidates to prioritize their perceived level of importance of 20 administrative dispositions. 128 school principals and 165 school leadership candidates in the NYC schools responded to an electronic…

  4. Widening the Discussion on HE Leadership--Leader Dispositions and Talents

    Science.gov (United States)

    Dunbar, D.

    2016-01-01

    What inherent personal leader qualities or dispositions do senior staff in universities say are necessary? What assumptions do we make about leadership in our universities and are they helpful? Are university staff surveys useful in giving both the leadership and staff a clear understanding of staff satisfaction levels related to how they are…

  5. Disposition of 14C-erythritol in germfree and conventional rats

    NARCIS (Netherlands)

    Ommen, B. van; Bie, B. de; Bar, A.

    1996-01-01

    The metabolism and disposition of U-14C-erythritol was examined in four groups of three male and three female, nonfasted rats each. The rats of groups A and D were germfree; the rats of groups B and C were kept under conventional conditions. The rats of group B received an erythritol-supplemented

  6. Disposition of 14C-α-cyclodextrin in germ-free and conventional rats

    NARCIS (Netherlands)

    Ommen, B. van; Bie, A.T.H.J. de; Bär, A.

    2004-01-01

    The absorption, disposition, metabolism, and excretion of uniformly 14C-labeled α-cyclodextrin (14C-α-CD) was examined in four separate experiments with Wistar rats. In Experiment 1, 14C-α-CD (25μCi, 50mg/kg bw) was administered intravenously to four male and four female conventional rats. In

  7. Predictors of psychological functioning in children with cancer: disposition and cumulative life stressors.

    Science.gov (United States)

    Howard Sharp, Katianne M; Rowe, Anjoli E; Russell, Kathryn; Long, Alanna; Phipps, Sean

    2015-07-01

    This study examined psychological functioning in children with a history of cancer and a matched sample of healthy peers, while exploring the roles of disposition and stressful life events. Participants were 255 children with a history of cancer and 101 demographically matched children (8-17 years). Children completed measures of depression, anxiety, and posttraumatic stress symptoms (PTSS); history of stressful life events; and dispositional factors, including optimism and a five-factor personality measure. Children with cancer did not differ from peers with regard to depression and PTSS, but reported significantly lower anxiety. In hierarchical regressions, children's depression, anxiety, and PTSS scores were largely predicted by dispositional variables and, to a lesser extent, stressful life events, after controlling for demographics and health status. Children's psychological functioning is predicted primarily by disposition, and secondarily by history of stressful life events, with health status (i.e., cancer versus control) accounting for minimal, and often non-significant variance in children's functioning. These findings further support that children with cancer are generally resilient, with factors predictive of their adjustment difficulties mirroring those of children without history of serious illness. Copyright © 2014 John Wiley & Sons, Ltd.

  8. 9 CFR 103.2 - Disposition of animals administered experimental biological products or live organisms.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Disposition of animals administered experimental biological products or live organisms. 103.2 Section 103.2 Animals and Animal Products ANIMAL AND... PRODUCTS; ORGANISMS AND VECTORS EXPERIMENTAL PRODUCTION, DISTRIBUTION, AND EVALUATION OF BIOLOGICAL...

  9. The Effect of Computer Games on Students' Critical Thinking Disposition and Educational Achievement

    Science.gov (United States)

    Seifi, Mohammad; Derikvandi, Zahra; Moosavipour, Saeed; Khodabandelou, Rouhollah

    2015-01-01

    The main aim of this research was to investigate the effect of computer games on student' critical thinking disposition and educational achievement. The research method was descriptive, and its type was casual-comparative. The sample included 270 female high school students in Andimeshk town selected by multistage cluster method. Ricketts…

  10. Critical Thinking Dispositions of Pre-Service Turkish Language Teachers and Primary Teachers

    Science.gov (United States)

    Maltepe, Sadet

    2016-01-01

    The present study aimed to determine critical thinking dispositions of pre-service Turkish language and primary teachers in terms of several variables by employing descriptive survey design. The study group consisted of 215 senior students attending Turkish Language Teaching and Primary Education Departments of Necatibey Faculty of Education at…

  11. Developing Reflective Dispositions through Collaborative Knowledge-Building during Small Group Bible Study

    Science.gov (United States)

    Toh, Tze Keong; Koh, Joyce Hwee Ling; Chai, Ching Sing

    2017-01-01

    This article explores the use of a constructivist pedagogical approach to cultivate reflective dispositions during small group Bible study. Conducted in a local church Bible class setting (n = 12), the instructional design emulated the reflective thinking process, while adopting collaborative knowledge-building as its pedagogical framework.…

  12. 9 CFR 327.25 - Disposition procedures for product condemned or ordered destroyed under import inspection.

    Science.gov (United States)

    2010-01-01

    ...; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION IMPORTED PRODUCTS § 327.25 Disposition procedures for product condemned or ordered destroyed under import inspection. (a... condemned or ordered destroyed under import inspection. 327.25 Section 327.25 Animals and Animal Products...

  13. Skills and Dispositions for Creative Problem Solving during the Artmaking Process

    Science.gov (United States)

    Pitri, Eliza

    2013-01-01

    In this article, Eliza Pitri states, "when allowed to make and explain their own choices, students develop invaluable creative problem-solving skills." Opportunities for such critical thinking abound in the art classroom. The importance of identifying how skills and dispositions related to creative problem solving are expressed in a…

  14. 19 CFR 12.40 - Seizure; disposition of seized articles; reports to United States attorney.

    Science.gov (United States)

    2010-04-01

    ... § 12.40 Seizure; disposition of seized articles; reports to United States attorney. (a) Any book....S. Attorney, for possible institution of condemnation proceedings, within 4 days, but in no event... already received information concerning the seizure pursuant to this paragraph, may proceed with the...

  15. Verb Disposition in Argument Structure Alternations: A Corpus Study of the Dative Alternation in Dutch

    Science.gov (United States)

    Colleman, Timothy

    2009-01-01

    Semantic accounts of verb pattern alternations often rely on observations about "verb disposition": the preference of verbs with particular lexical semantic characteristics for one of two competing constructions is taken as a clue to the semantic differences between the two constructions. For instance, it has been observed with regard to the…

  16. Are College Students' Textbook Reading and Instructional Preferences Related to Their Self-Efficacy and Disposition?

    Science.gov (United States)

    Skidmore, Ronald L.; Conner, Timothy W., II; Aagaard, Lola

    2013-01-01

    The purpose of this study was to investigate the relationship between academic self-efficacy, dispositional optimism/pessimism, and preferences regarding the use of text materials and in-class activities of college students at a university that serves one of the highest-poverty regions in the United States. A sample of 105 students was surveyed.…

  17. Student Disposition, Textbooks, and Class Time: What Do They Really Want?

    Science.gov (United States)

    Skidmore, Ronald L.; Aagaard, Lola; Conner, Timothy W., II

    2011-01-01

    The purpose of this study was to determine the relationship between student beliefs regarding instructor-imposed activities to encourage student use of course textbooks and Life Orientation (i.e., dispositional optimism or pessimism). A convenience cluster sample (n = 105) was obtained from students taking summer classes at a regional state…

  18. Dispositional Employability and Online Training Purchase. Evidence from Employees' Behavior in Spain.

    Science.gov (United States)

    Torrent-Sellens, Joan; Ficapal-Cusí, Pilar; Boada-Grau, Joan

    2016-01-01

    This article explores the relationship between dispositional employability and online training purchase. Through a sample of 883 employees working for enterprises in Spain, and a using principal component analysis and binomial logit probabilistic models, the research revealed two main results. First, it was found that dispositional employability is characterized by five factors: "openness to changes at work," "career motivation and work resilience," "work and career proactivity," "optimism and engagement at work," and "work identity." Second, the research also found a double causality in the relationship analysis between dispositional employability and online training purchase. However, this causality is not direct. In explaining dispositional employability, certain motivations and types of behavior of employees participating in online training are significant. In particular, greater sensitivity toward career-related personal empowerment, a greater predisposition toward developing new experiences at work, and a greater awareness of the fact that positive job outcomes are related to preparation conscientiousness. In explaining online training purchase, employees who are more motivated and who better identify with their jobs are more likely to pay. Moreover, employees who spend more time on training and have less contact with new trends in their jobs, find it hard to keep calm in difficult situations, and have a greater predisposition toward effort, and preference for novelty, variety and challenges at work are more likely to purchase online training.

  19. Moral sensitivity and critical thinking disposition of nursing students in Korea.

    Science.gov (United States)

    Ahn, Sung-Hee; Yeom, Hye-A

    2014-10-01

    This study aimed to examine the level of moral sensitivity and critical thinking disposition among baccalaureate nursing students in Korea. A convenience sample of 142 undergraduate nursing students was surveyed on moral sensitivity using the Korean version of the Moral Sensitivity Questionnaire (K-MSQ) and on critical thinking disposition using the Critical Thinking Disposition Questionnaire (CTDQ). Data were collected from June 2009 to July 2010. Mean score was 2.83 out of 7 on the K-MSQ (relatively low) and 3.70 out of 5 on the CTDQ (relatively high), indicating the need for nursing educators to continue to develop and incorporate strategies that enhance moral sensitivity into ethics courses in undergraduate nursing programs in Korea. Nursing students who regarded nursing as a lifelong career exhibited stronger critical thinking disposition than did students who considered nursing to be a temporary or premarital job. Moral sensitivity should be further emphasized in nursing ethics courses in undergraduate nursing programs in Korea. © 2013 Wiley Publishing Asia Pty Ltd.

  20. Technology Facilitated PBL Pedagogy and Its Impact on Nursing Students' Academic Achievement and Critical Thinking Dispositions

    Science.gov (United States)

    Yu, Wei-Chieh Wayne; Lin, Chunfu Charlie; Ho, Mei-Hsin; Wang, Jenny

    2015-01-01

    The impact of particular learning environments and self-regulation could be a beneficial area for research focus. More specifically, there has not been sufficient attention given to the role played by disposition or "will" in facilitating self-regulation to be successful. A student can possess the skills or ability to think critically…

  1. 22 CFR 136.4 - Restrictions on dispositions of personal property.

    Science.gov (United States)

    2010-04-01

    ... international law. (f) Violations of the restrictions or requirements of paragraphs (a) through (e) of this... country in accordance with the laws or regulations of that country. (c) Profits obtained from dispositions... employer or family member in unusual or commercial quantities was not acquired for bona fide personal use...

  2. Virtual Teaching Dispositions in an Open Distance Learning Environment: Origins, Measurement and Impact

    Science.gov (United States)

    Martins, Nico; Ungerer, Leona M.

    2017-01-01

    An understanding of the key characteristics and implicit competencies underlying online teaching is essential to distance education institutions that embark on the assertive use of technology in their tuition development and delivery. The Virtual Teaching Dispositions Scale (VTDS) assists in investigating professional teaching dispositions…

  3. Nurbayev D.M. Public and dispositive segments of abuse of the subjective right: interdisciplinary look.

    Directory of Open Access Journals (Sweden)

    Vladimir Azarov

    2017-01-01

    Full Text Available УДК 343.12The subject. The article is devoted to the analysis of a phenomenon "abuse of the right" from a position of the public and dispositive beginnings of his manifestation.The purpose of this article is to consider public and dispositive principles of abuse of the right in the scope of legal theory to qualify this phenomenon in criminal proceedings properly.Methodology. The author use methods of theoretical analysis and interdisciplinary approach as well as legal methods, including formal legal method and comparative law.Results, scope of it’s application. The authors note that the use of the advantages offered by abuse of the right is initially inherent only for the defending party in criminal proceedings.Abuse of the right in the procedural segment of disposition appears in the implementation of the right to protection in the criminal procedure as well as in the implementation of almost any rights in the civil proceedings.The main resource of publicity is realized exclusively by the courts in the civil procedure as well as by all government entities and officials in the criminal process. That’s why abuse of the right is interdicted by the activity of the court in civil procedure.The imperative method of legal regulation of public relations, that is the basis of publicity, is in fact one of the ways of prevention and suppression of abuse of rights. The disposition method, that is the basis of competition in legal relations, is a catalyst for the creation of situations of possible abuse of rights.Abuse of rights is manifested first and foremost in terms of the disposition, moreover – the higher the level of disposition in the particular branch of law provokes the greater likelihood of abuse of the right. Publicity limits disposition and, therefore, the possibility of abuse of the right.Conclusions. Legal institute of abuse of right requires early normative entrenchment in the criminal process. It should contain specific grounds for

  4. Dispositional optimism as predictor of outcome in short- and long-term psychotherapy.

    Science.gov (United States)

    Heinonen, Erkki; Heiskanen, Tiia; Lindfors, Olavi; Härkäpää, Kristiina; Knekt, Paul

    2017-09-01

    Dispositional optimism predicts various beneficial outcomes in somatic health and treatment, but has been little studied in psychotherapy. This study investigated whether an optimistic disposition differentially predicts patients' ability to benefit from short-term versus long-term psychotherapy. A total of 326 adult outpatients with mood and/or anxiety disorder were randomized into short-term (solution-focused or short-term psychodynamic) or long-term psychodynamic therapy and followed up for 3 years. Dispositional optimism was assessed by patients at baseline with the self-rated Life Orientation Test (LOT) questionnaire. Outcome was assessed at baseline and seven times during the follow-up, in terms of depressive (BDI, HDRS), anxiety (SCL-90-ANX, HARS), and general psychiatric symptoms (SCL-90-GSI), all seven follow-up points including patients' self-reports and three including interview-based measures. Lower dispositional optimism predicted faster symptom reduction in short-term than in long-term psychotherapy. Higher optimism predicted equally rapid and eventually greater benefits in long-term, as compared to short-term, psychotherapy. Weaker optimism appeared to predict sustenance of problems early in long-term therapy. Stronger optimism seems to best facilitate engaging in and benefiting from a long-term therapy process. Closer research might clarify the psychological processes responsible for these effects and help fine-tune both briefer and longer interventions to optimize treatment effectiveness for particular patients and their psychological qualities. Weaker dispositional optimism does not appear to inhibit brief therapy from effecting symptomatic recovery. Patients with weaker optimism do not seem to gain added benefits from long-term therapy, but instead may be susceptible to prolonged psychiatric symptoms in the early stages of long-term therapy. © 2016 The British Psychological Society.

  5. Teachers' dispositional mindfulness and the quality of their relationships with children in Head Start classrooms.

    Science.gov (United States)

    Becker, Brandon D; Gallagher, Kathleen C; Whitaker, Robert C

    2017-12-01

    The quality of teachers' relationships with children is a key predictor of children's later social emotional competence and academic achievement. Interventions to increase mindfulness among teachers have focused primarily on the impacts on teachers' subjective well-being, but not on the quality of their relationships with children. Furthermore, none of these interventions have involved preschool teachers. To consider the potential of mindfulness-based interventions to improve the quality of teachers' relationships with preschool-aged children, we examined data from an online survey of 1001 classroom teachers in 37 Pennsylvania Head Start Programs. Using path analysis we investigated the association between teachers' dispositional mindfulness and the quality of their relationships with children (conflict and closeness). We further examined whether this association was mediated by teacher depressive symptoms and moderated by perceived workplace stress. Higher levels of dispositional mindfulness among teachers were associated with higher quality relationships with children (less conflict and greater closeness). The association between greater dispositional mindfulness and less conflict was partially mediated by lower depressive symptoms, and the conditional direct effect of mindfulness on conflict was stronger when perceived workplace stress was lower. These findings suggest that preschool teachers who have higher levels of dispositional mindfulness may experience higher quality relationships with children in their classrooms. Interventions to increase levels of dispositional mindfulness among early childhood educators may improve their well-being along with the quality of their relationships with children, potentially impacting children's educational outcomes. The potential impacts of such interventions may be even stronger if structural and systemic changes are also made to reduce workplace stress. Copyright © 2017 Society for the Study of School Psychology

  6. LLNL MOX fuel lead assemblies data report for the surplus plutonium disposition environmental impact statement

    Energy Technology Data Exchange (ETDEWEB)

    O`Connor, D.G.; Fisher, S.E.; Holdaway, R. [and others

    1998-08-01

    The purpose of this document is to support the US Department of Energy (DOE) Fissile Materials Disposition Program`s preparation of the draft surplus plutonium disposition environmental impact statement. This is one of several responses to data call requests for background information on activities associated with the operation of the lead assembly (LA) mixed-oxide (MOX) fuel fabrication facility. The DOE Office of Fissile Materials Disposition (DOE-MD) has developed a dual-path strategy for disposition of surplus weapons-grade plutonium. One of the paths is to disposition surplus plutonium through irradiation of MOX fuel in commercial nuclear reactors. MOX fuel consists of plutonium and uranium oxides (PuO{sub 2} and UO{sub 2}), typically containing 95% or more UO{sub 2}. DOE-MD requested that the DOE Site Operations Offices nominate DOE sites that meet established minimum requirements that could produce MOX LAs. LLNL has proposed an LA MOX fuel fabrication approach that would be done entirely inside an S and S Category 1 area. This includes receipt and storage of PuO{sub 2} powder, fabrication of MOX fuel pellets, assembly of fuel rods and bundles, and shipping of the packaged fuel to a commercial reactor site. Support activities will take place within a Category 1 area. Building 332 will be used to receive and store the bulk PuO{sub 2} powder, fabricate MOX fuel pellets, and assemble fuel rods. Building 334 will be used to assemble, store, and ship fuel bundles. Only minor modifications would be required of Building 332. Uncontaminated glove boxes would need to be removed, petition walls would need to be removed, and minor modifications to the ventilation system would be required.

  7. Developing critical thinking disposition and emotional intelligence of nursing students: a longitudinal research.

    Science.gov (United States)

    Kaya, Hülya; Şenyuva, Emine; Bodur, Gönül

    2017-01-01

    Emotional Intelligence is considered as an important characteristic of nurses that can affect the quality of their work including clinical decision-making, critical thinking, evidence and knowledge use in practice. The study is aimed to determine nursing students' critical thinking disposition and emotional intelligence in an academic year. A longitudinal design. The focus population of this longitudinal study consists of 197 freshman students studying at a faculty of nursing. Asymmetrical cluster sampling method was used to determine sample group and all the students registered in the first year were included in scope of the study. Information Form, California Critical Thinking Disposition Scale and Emotional Intelligence Assessment Scale were used for data collection. SPSS version 11.5 was used for data analysis. Nursing students have a low level of critical thinking disposition and intermediate level of emotional intelligence both at the beginning and end of academic year. There was no statistically significant difference in both skills at the beginning and end of year. There was a statistically significant difference between students' critical thinking disposition and emotional intelligence at the beginning of academic year. There was a positive correlation at a medium level between students' critical thinking disposition and emotional intelligence at the beginning and end of academic year. In light of these results, it is that suggested the study should be prolonged as longitudinal because development of both skills require a long time. The current study holds importance that it sheds light on other relevant studies and nursing education programs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Study of plutonium disposition using the GE Advanced Boiling Water Reactor (ABWR)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-04-30

    The end of the cold war and the resulting dismantlement of nuclear weapons has resulted in the need for the U.S. to disposition 50 to 100 metric tons of excess of plutonium in parallel with a similar program in Russia. A number of studies, including the recently released National Academy of Sciences (NAS) study, have recommended conversion of plutonium into spent nuclear fuel with its high radiation barrier as the best means of providing long-term diversion resistance to this material. The NAS study {open_quotes}Management and Disposition of Excess Weapons Plutonium{close_quotes} identified light water reactor spent fuel as the most readily achievable and proven form for the disposition of excess weapons plutonium. The study also stressed the need for a U.S. disposition program which would enhance the prospects for a timely reciprocal program agreement with Russia. This summary provides the key findings of a GE study where plutonium is converted into Mixed Oxide (MOX) fuel and a 1350 MWe GE Advanced Boiling Water Reactor (ABWR) is utilized to convert the plutonium to spent fuel. The ABWR represents the integration of over 30 years of experience gained worldwide in the design, construction and operation of BWRs. It incorporates advanced features to enhance reliability and safety, minimize waste and reduce worker exposure. For example, the core is never uncovered nor is any operator action required for 72 hours after any design basis accident. Phase 1 of this study was documented in a GE report dated May 13, 1993. DOE`s Phase 1 evaluations cited the ABWR as a proven technical approach for the disposition of plutonium. This Phase 2 study addresses specific areas which the DOE authorized as appropriate for more in-depth evaluations. A separate report addresses the findings relative to the use of existing BWRs to achieve the same goal.

  9. Pediatric early warning score at time of emergency department disposition is associated with level of care.

    Science.gov (United States)

    Breslin, Kristen; Marx, Julie; Hoffman, Heather; McBeth, Ryan; Pavuluri, Padmaja

    2014-02-01

    The objective of this study was to determine the association between the Pediatric Early Warning Score (PEWS) at time of emergency department (ED) disposition and level of care. We conducted a prospective observational study with a convenience sample of patients aged 0 to 21 years in the ED of an urban, tertiary care children's hospital between November 2010 and July 2011. Pediatric Early Warning Score data were obtained at time of ED disposition, and the disposition decision was collected from the electronic medical record. Multinomial logistic regression was used to determine the association between PEWS and disposition. The sample of 383 patients included 239 (62%) who were discharged, 126 (33%) admitted to acute care, and 18 (5%) admitted to intensive care. Assigned scores ranged from 0 to 9. Adjusting for triage level, a 1-point increase in PEWS increased the odds of acute care admission 48% relative to the odds of discharge (odds ratio, 1.48; 95% confidence interval, 1.25-1.76) and increased the odds of intensive care admission 41% relative to the odds of acute care admission (odds ratio, 1.41; 95% confidence interval, 1.13-1.76). Pediatric Early Warning Score of 1 or more had maximum discriminant ability for admission, and PEWS of 3 or greater had maximum discriminant ability for intensive care. Area under the receiver operator characteristic curve was 0.68 to detect need for admission for the entire sample and 0.80 among the 97 patients with respiratory complaints. Pediatric Early Warning Score is associated with the level of care at ED disposition but does not provide adequate sensitivity and specificity to be used in isolation. Performance characteristics are better for patients with respiratory complaints.

  10. Associations among dispositional mindfulness, self-compassion, and executive function proficiency in early adolescents.

    Science.gov (United States)

    Shin, Hee-Sung; Black, David S; Shonkoff, Eleanor Tate; Riggs, Nathaniel R; Pentz, Mary Ann

    2016-12-01

    The study objective was to examine the effects of two conceptually related constructs, self-compassion and dispositional mindfulness, on executive function (EF) proficiency among early adolescents. Executive function refers to a set of psychological processes governing emotional regulation, organization, and planning. While the benefits of positive psychology appear evident for mental health and wellness, little is known about the etiological relationship between dispositional mindfulness and self-compassion in their associations with EF. Two hundred and ten early adolescents attending middle school (age M=12.5 years; SD=0.5; 21% Hispanic, 18% Mixed/bi-racial, 47% White, and 9% Other/Missing; 37.1% on free lunch program) self-reported levels of dispositional mindfulness (Mindful Attention Awareness Scale; MAAS), self-compassion (Self-Compassion Scale; SCS; self-judgment and self-kindness domains), and EF proficiency (Behavior Rating Inventory of Executive Function; BRIEF-SR). A sequential linear regression stepwise approach was taken entering the independent variables as separate models in the following order: self-kindness, self-judgement, and dispositional mindfulness. All models controlled for participant age and sex. SCS self-kindness was not associated with EF proficiency, but SCS self-judgment (reverse-coded) contributed to the variance in EF (β=0.40, p<.001). When adding MAAS to the model, MAAS scores were significantly associated with EF (β=0.64, p<.001) and accounted for the initial variance explained by SCS. When considering the influence of positive psychology constructs on EF proficiency in adolescents, the measure of dispositional mindfulness appears to outweigh that of specific self-compassion domains, when independent of contemplative training.

  11. Emotional intelligence moderates the relationship between regional gray matter volume in the bilateral temporal pole and critical thinking disposition.

    Science.gov (United States)

    Yao, Xiaonan; Yuan, Shuge; Yang, Wenjing; Chen, Qunlin; Wei, Dongtao; Hou, Yuling; Zhang, Lijie; Qiu, Jiang; Yang, Dong

    2017-03-29

    Critical thinking enables people to form sound beliefs and provides a basis for emotional life. Research has indicated that individuals with better critical thinking disposition can better recognize and regulate their emotions, though the neuroanatomical mechanisms involved in this process remain to be elucidated. Further, the influence of emotional intelligence on the relationship between brain structure and critical thinking disposition has not been examined. The present study utilized voxel-based morphometry (VBM) to investigate the neural structures underlying critical thinking disposition in a large sample of college students (N = 296). Regional gray matter volume (rGMV) in the bilateral temporal pole, which reflects an individual's ability to process social and emotional information, was negatively correlated with critical thinking disposition. In addition, rGMV in bilateral para hippocampal regions -regions involved in contextual association/emotional regulation-exhibited negative correlation with critical thinking disposition. Further analysis revealed that emotional intelligence moderated the relationship between rGMV of the temporal pole and critical thinking disposition. Specifically, critical thinking disposition was associated with decreased GMV of the temporal pole for individuals who have relatively higher emotional intelligence rather than lower emotional intelligence. The results of the present study indicate that people who have higher emotional intelligence exhibit more effective and automatic processing of emotional information and tend to be strong critical thinkers.

  12. Modeling the kinetics of vulcanization polydienes

    National Research Council Canada - National Science Library

    V. I. Molchanov; O. V. Karmanova; S. G. Tikhomirov

    2013-01-01

    A model of vulcanization kinetics, which allows describing the kinetic curves of any form and on the basis of economical laboratory experiment analytically evaluate the kinetics of isothermal curing was proposed...

  13. Quantifying mitochondrial and plasma membrane potentials in intact pulmonary arterial endothelial cells based on extracellular disposition of rhodamine dyes

    Science.gov (United States)

    Gan, Zhuohui; Audi, Said H.; Bongard, Robert D.; Gauthier, Kathryn M.

    2011-01-01

    Our goal was to quantify mitochondrial and plasma potential (Δψm and Δψp) based on the disposition of rhodamine 123 (R123) or tetramethylrhodamine ethyl ester (TMRE) in the medium surrounding pulmonary endothelial cells. Dyes were added to the medium, and their concentrations in extracellular medium ([Re]) were measured over time. R123 [Re] fell from 10 nM to 6.6 ± 0.1 (SE) nM over 120 min. TMRE [Re] fell from 20 nM to a steady state of 4.9 ± 0.4 nM after ∼30 min. Protonophore or high K+ concentration ([K+]), used to manipulate contributions of membrane potentials, attenuated decreases in [Re], and P-glycoprotein (Pgp) inhibition had the opposite effect, demonstrating the qualitative impact of these processes on [Re]. A kinetic model incorporating a modified Goldman-Hodgkin-Katz model was fit to [Re] vs. time data for R123 and TMRE, respectively, under various conditions to obtain (means ± 95% confidence intervals) Δψm (−130 ± 7 and −133 ± 4 mV), Δψp (−36 ± 4 and −49 ± 4 mV), and a Pgp activity parameter (KPgp, 25 ± 5 and 51 ± 11 μl/min). The higher membrane permeability of TMRE also allowed application of steady-state analysis to obtain Δψm (−124 ± 6 mV). The consistency of kinetic parameter values obtained from R123 and TMRE data demonstrates the utility of this experimental and theoretical approach for quantifying intact cell Δψm and Δψp. Finally, steady-state analysis revealed that although room air- and hyperoxia-exposed (95% O2 for 48 h) cells have equivalent resting Δψm, hyperoxic cell Δψm was more sensitive to depolarization with protonophore, consistent with previous observations of pulmonary endothelial hyperoxia-induced mitochondrial dysfunction. PMID:21239539

  14. Nurse Middle Managers' Dispositions of Habitus: A Bourdieusian Analysis of Supporting Role Behaviors in Dutch and American Hospitals.

    Science.gov (United States)

    Lalleman, P C B; Smid, G A C; Lagerwey, M D; Oldenhof, L; Schuurmans, M J

    2015-01-01

    A Magnet-related program has been recently adopted in the Netherlands. Support for staff nurses from nurse middle managers (NMMs) is a key component of such a program. A Bourdieusian ethnographic organizational case study in 4 hospitals in the Netherlands and the United States (Magnet, Magnet-related, and non-Magnet) was conducted to explore NMMs' supporting role behavior. Bourdieus concepts of habitus, field, and capital guided the analysis. Eight dispositions constitute NMMs habitus. A caring, clinical, and scientific disposition enhances NMMs' capital in particular organizations-as-fields. Further research is necessary to link Magnet (-related) program characteristics to various configurations of dispositions of NMMs habitus.

  15. Kinetics of Levoglucosenone Isomerization.

    Science.gov (United States)

    Krishna, Siddarth H; Walker, Theodore W; Dumesic, James A; Huber, George W

    2017-01-10

    We studied the acid-catalyzed isomerization of levoglucosenone (LGO) to 5-hydroxymethylfurfural (HMF) and developed a reaction kinetics model that describes the experimental data across a range of conditions (100-150 °C, 50-100 mm H2 SO4 , 50-150 mm LGO). LGO and its hydrated derivative exist in equilibrium under these reaction conditions. Thermal and catalytic degradation of HMF are the major sources of carbon loss. Within the range of conditions studied, higher temperatures and shorter reaction times favor the production of HMF. The yields of HMF and levulinic acid decrease monotonically as tetrahydrofuran is added to the aqueous solvent system, indicating that water plays a role in the LGO isomerization reaction. Initial-rate analyses show that HMF is produced solely from LGO rather than from the hydrated derivative of LGO. The results of this study are consistent with a mechanism for LGO isomerization that proceeds through hydration of the anhydro bridge, followed by ring rearrangement analogous to the isomerization of glucose to fructose. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Kinetic properties of cyanase.

    Science.gov (United States)

    Anderson, P M; Little, R M

    1986-04-08

    Cyanase is an inducible enzyme in Escherichia coli that catalyzes the hydrolysis of cyanate. Bicarbonate is required for activity, perhaps as a substrate, and the initial product of the reaction is carbamate, which spontaneously breaks down to ammonia and bicarbonate [Anderson, P. M. (1980) Biochemistry 19, 2882]. The purpose of this study was to characterize the kinetic properties of cyanase. Initial velocity studies showed that both cyanate and bicarbonate act as competitive substrate inhibitors. A number of monovalent anions act as inhibitors. Azide and acetate appear to act as competitive inhibitors with respect to cyanate and bicarbonate, respectively. Chloride, bromide, nitrate, nitrite, and formate also inhibit, apparently as the result of binding at either substrate site. Malonate and several other dicarboxylic dianions at very low concentrations display "slow-binding", reversible inhibition which can be prevented by saturating concentrations of either substrate. The results are consistent with a rapid equilibrium random mechanism in which bicarbonate acts as a substrate, bicarbonate and cyanate bind at adjacent anion-binding sites, and both substrates can bind at the other substrate anion binding site to give a dead-end complex.

  17. Used fuel disposition research and development roadmap - FY10 status.

    Energy Technology Data Exchange (ETDEWEB)

    Nutt, W. M. (Nuclear Engineering Division)

    2010-10-01

    Since 1987 the U.S. has focused research and development activities relevant to the disposal of commercial used nuclear fuel and U.S. Department of Energy (DOE) owned spent nuclear fuel and high level waste on the proposed repository at Yucca Mountain, Nevada. At the same time, the U.S. successfully deployed a deep geologic disposal facility for defense-related transuranic waste in bedded salt at the Waste Isolation Pilot Plant. In 2009 the DOE established the Used Fuel Disposition Campaign (UFDC) within the Office of Nuclear Energy. The Mission of the UFDC is to identify alternatives and conduct scientific research and technology development to enable storage, transportation and disposal of used nuclear fuel and wastes generated by existing and future nuclear fuel cycles. The U.S. national laboratories have participated on these programs and has conducted research and development related to these issues to a limited extent. However, a comprehensive research and development (R&D) program investigating a variety of geologic media has not been a part of the U.S. waste management program since the mid 1980s. Such a comprehensive R&D program is being developed in the UFDC with a goal of meeting the UFDC Grand Challenge to provide a sound technical basis for absolute confidence in the safety and security of long-term storage, transportation, and disposal of used nuclear fuel and wastes from the nuclear energy enterprise. The DOE has decided to no longer pursue the development of a repository at Yucca Mountain, Nevada. Since a repository site will ultimately have to be selected, sited, characterized, designed, and licensed, other disposal options must now be considered. In addition to the unsaturated volcanic tuff evaluated at Yucca Mountain, several different geologic media are under investigation internationally and preliminary assessments indicate that disposal of used nuclear fuel and high level waste in these media is feasible. Considerable progress has been made in

  18. Effect of an endurance-like exercise on the disposition and detection time of phenylbutazone and dexamethasone in the horse: application to medication control.

    Science.gov (United States)

    Authie, E C; Garcia, P; Popot, M A; Toutain, P L; Doucet, M

    2010-04-01

    Equine antidoping rules were established to prevent a horse's performance being altered after the administration of prohibited substances, including approved drugs used for legitimate treatment. Veterinarians have to advise owners or trainers on appropriate withholding times to guarantee that their horses may safely compete after drug administration. In order to propose tailored withdrawal times, several horse organisations released detection time (DT) values, for the main veterinary drugs used in horses. One of the possible limits to the information provided by published DTs in horses is the fact that they are determined from classic pharmacokinetic studies performed at rest under laboratory conditions. In field conditions, training and exercise programmes may have an influence on drug elimination. Dexamethasone (DMX) and phenylbutazone (PBZ) have been quantified in plasma and urine after solid phase extraction. The kinetic disposition of DXM (8 microg/kg) and PBZ (8 mg/kg) administered by i.v. route in 8 horses, was investigated in rest conditions and during a standardised 3 h test exercise according to a cross-over design. The aim of the present study was to compare the kinetic disposition of 2 test drugs, DMX and PBZ in rest vs. exercising conditions. It was shown in 8 horses that a sustained 3 h of mild exercise slightly decreased the plasma clearance of both drugs (about 25% for DXM and 37% for PBZ) and this is mainly explained by the significant decrease of the corresponding hepatic clearance. In addition, as the volume of distribution was correlatively decreased, the plasma terminal half-life, which is a hybrid parameter of plasma clearance and volume of distribution, remains unchanged overall. Establishing DTs or withdrawal times (WTs) are relevant as plasma and urine half-lives, but not clearance, are the main determinants of DT length. Veterinarians may realistically decide upon a WT for a legitimate drug based on the corresponding DT obtained under

  19. University and Elementary School Perspectives of Ideal Elementary Science Teacher Knowledge, Skills, and Dispositions

    Science.gov (United States)

    Sewart, Bethany Bianca

    Teacher education knowledge, skills, and dispositions have recently become a well-discussed topic among education scholars around the nation, mainly due to its attention by the National Council for Accreditation of Teacher Education (NCATE) over the past few years. Accrediting agencies, such as NCATE and the Interstate New Teacher and Assessment and Support Consortium (INTASC), have sought to improve the quality of teacher education programs by examining knowledge, skills, and dispositions as factors in preparing highly-qualified teachers. There is a paucity of research examining these factors for elementary science teachers. Because these factors influence instruction, and students are behind in scientific and mathematical knowledge, elementary science teachers should be studied. Teacher knowledge, skills, and dispositions should be further researched in order to ultimately increase the quality of teachers and teacher education programs. In this particular case, by determining what schools of education and public schools deem important knowledge, skills, and dispositions needed to teach science, higher education institutions and schools can collaborate to further educate these students and foster the necessary qualities needed to teach effectively. The study of knowledge, skills, and dispositions is crucial to nurturing effective teaching within the classroom. Results from this study demonstrated that there were prominent knowledge, skills, and dispositions identified by teachers, administrators, and science teacher educators as important for effective teaching of elementary science. These characteristics included: a willingness to learn, or open-mindedness; content knowledge; planning, organization, and preparation; significance of teaching science; and science-related assessment strategies. Interestingly, administrators in the study responded differently than their counterparts in the following areas: their self-evaluation of teacher effectiveness; how the

  20. Kinetic ELISA in microfluidic channels

    National Research Council Canada - National Science Library

    Yanagisawa, Naoki; Dutta, Debashis

    2011-01-01

    In this article, we describe the kinetic ELISA of Blue Tongue and Epizootic Hemorrhagic Disease viral antibodies in microfluidic channels by monitoring the rate of generation of the enzyme reaction...

  1. Modelling Heart Rate Kinetics

    Science.gov (United States)

    Zakynthinaki, Maria S.

    2015-01-01

    The objective of the present study was to formulate a simple and at the same time effective mathematical model of heart rate kinetics in response to movement (exercise). Based on an existing model, a system of two coupled differential equations which give the rate of change of heart rate and the rate of change of exercise intensity is used. The modifications introduced to the existing model are justified and discussed in detail, while models of blood lactate accumulation in respect to time and exercise intensity are also presented. The main modification is that the proposed model has now only one parameter which reflects the overall cardiovascular condition of the individual. The time elapsed after the beginning of the exercise, the intensity of the exercise, as well as blood lactate are also taken into account. Application of the model provides information regarding the individual’s cardiovascular condition and is able to detect possible changes in it, across the data recording periods. To demonstrate examples of successful numerical fit of the model, constant intensity experimental heart rate data sets of two individuals have been selected and numerical optimization was implemented. In addition, numerical simulations provided predictions for various exercise intensities and various cardiovascular condition levels. The proposed model can serve as a powerful tool for a complete means of heart rate analysis, not only in exercise physiology (for efficiently designing training sessions for healthy subjects) but also in the areas of cardiovascular health and rehabilitation (including application in population groups for which direct heart rate recordings at intense exercises are not possible or not allowed, such as elderly or pregnant women). PMID:25876164

  2. Alternative technical summary report for immobilized disposition in deep boreholes: Immobilized disposal of plutonium in coated ceramic pellets in grout without canisters, Version 4.0. Fissile materials disposition program

    Energy Technology Data Exchange (ETDEWEB)

    Wijesinghe, A.M.

    1996-08-23

    This paper summarizes and compares the immobilized and direct borehole disposition alternatives previously presented in the alternative technical summary. The important design concepts, facility features and operational procedures are first briefly described. This is followed by a discussion of the issues that affect the evaluation of each alternative against the programmatic assessment criteria that have been established for selecting the preferred alternatives for plutonium disposition.

  3. Effects of vehicle on the uptake and elimination kinetics of capsaicinoids in human skin in vivo.

    Science.gov (United States)

    Pershing, Lynn K; Reilly, Christopher A; Corlett, Judy L; Crouch, Dennis J

    2004-10-01

    While the physiologic and molecular effects of capsaicinoids have been extensively studied in various model systems by a variety of administration routes, little is known about the uptake and elimination kinetic profiles in human skin following topical exposure. The present study evaluated the uptake and elimination kinetics of capsaicinoids in human stratum corneum following a single topical exposure to 3% solutions containing 55% capsaicin, 35% dihydrocapsaicin, and 10% other analogues prepared in three vehicles: mineral oil (MO), propylene glycol (PG), and isopropyl alcohol (IPA). Capsaicinoid solutions were evaluated simultaneously in a random application pattern on the volar forearms of 12 subjects using a small, single 150-microg dose. Capsaicin and dihydrocapsaicin were recovered from human skin using commercial adhesive discs to harvest stratum corneum from treated sites. Capsaicinoids were extracted from the stratum corneum-adhesive discs and quantified by liquid chromatography/mass spectroscopy (LC/MS). Both capsaicinoids were detected in stratum corneum 1 min after application with all vehicles and achieved a pseudo-steady state shortly thereafter. IPA delivered three times greater capsaicin and dihydrocapsaicin into the human stratum corneum than PG or MO at all time points investigated. The Cmax of capsaicin in IPA, PG, and MO was 16.1, 6.2, and 6.5 microg, respectively. The dihydrocapsaicin content was 60% of capsaicin with all vehicles. The estimated T(half) of capsaicin and dihydrocapsaicin in the three vehicles was similar (24 h). Thus, maximal cutaneous capsaicinoid concentrations were achieved quickly in the human stratum corneum and were concentration and vehicle dependent. In contrast, capsaicinoid half-life was long and vehicle independent.

  4. The Effects of Reflective Training on the Disposition of Critical Thinking for Nursing Students in China: A Controlled Trial

    Directory of Open Access Journals (Sweden)

    Caihong Zhang, Ph.D.

    2017-09-01

    Conclusion: Reflective training during the internship period improves nursing students' disposition of critical thinking and promotes their readiness for their clinical practices in the rapidly increasing demands of the healthcare field.

  5. Dispositional Mindfulness as a Moderator of the Relationship Between Perceived Partner Infidelity and Women's Dating Violence Perpetration.

    Science.gov (United States)

    Brem, Meagan J; Wolford-Clevenger, Caitlin; Zapor, Heather; Elmquist, Joanna; Shorey, Ryan C; Stuart, Gregory L

    2015-09-08

    Mindfulness gained increased attention as it relates to aggressive behavior, including dating violence. However, no known studies examined how the combined influences of dispositional mindfulness and perceived partner infidelity, a well-documented correlate of dating violence, relate to women's dating violence perpetration. Using a sample of college women (N = 203), we examined the relationship between perceived partner infidelity and physical dating violence perpetration at varying levels of dispositional mindfulness, controlling for the influence of alcohol use. Results indicated perceived partner infidelity and dating violence perpetration were positively related for women with low and mean dispositional mindfulness, but not for women with high dispositional mindfulness. These results further support the applicability of mindfulness theory in the context of dating violence. Implications of the present findings provide preliminary support for mindfulness intervention in relationships characterized by infidelity concerns. © The Author(s) 2015.

  6. Combining dispositions and evaluations of vocation and job to account for counterproductive work behavior in adolescent job apprentices.

    Science.gov (United States)

    Marcus, Bernd; Wagner, Uwe

    2007-04-01

    In the present research, we investigated the joint impact of selected antecedents of counterproductive work behavior (CWB). A sample of German apprentices reported on their CWB and completed measures of situational evaluations (vocational preference, level and constructiveness of job satisfaction) believed to trigger CWB and of dispositional motivators (measured by integrity test subscales) and controls (self-control and another subset of integrity scales) of CWB. All predictors investigated showed the expected bivariate relationships with CWB. Multivariate analyses revealed that the triggering effect of an unfavorable vocational choice on CWB was fully mediated by job satisfaction. When predictors were aggregated, a composite of dispositional control variables had the largest effect on CWB and moderated the effects of motivational dispositions and situational evaluations. These results extend the knowledge on antecedents of CWB by investigating previously overlooked variables and samples and partially replicate recent findings on the joint impact of dispositions and work-related evaluations on CWB. Copyright (c) 2007 APA, all rights reserved.

  7. An Improved Modulation Strategy Combining Phase Shifted PWM and Phase Disposition PWM for Cascaded H-Bridge Inverters

    National Research Council Canada - National Science Library

    Muxuan Xiao; Qianming Xu; Honglin Ouyang

    2017-01-01

    .... In this paper, the relationship between phase-shifted pulse width modulation (PWM) and phase disposition PWM is analyzed, and then an improved hybrid modulation strategy is proposed for cascaded H-bridge...

  8. Identifying dispositions for youth leadership development through an adapted action research methodology in a youth-related organization in Singapore

    OpenAIRE

    Ang, Chun Ling Philip

    2017-01-01

    This thesis sets out to investigate and identify the dispositions that youth in leadership positions may find useful for personal or organizational leadership development purposes. The research approach and process involved using an adapted action research methodology to identify such leadership dispositions and situates youth leadership development in the context of engaging youths in social capital initiatives. Findings from this study contributes to an understanding of how leadership disp...

  9. Possible Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Disposition of Azithromycin

    OpenAIRE

    Sugie, Masami; Asakura, Emiko; Zhao, Ying Lan; Torita, Shoko; Nadai, Masayuki; Baba, Kenji; Kitaichi, Kiyoyuki; Takagi, Kenji; Takagi, Kenzo; HASEGAWA, Takaaki

    2004-01-01

    P glycoprotein and multidrug resistance-associated protein 2 (Mrp2), ATP-dependent membrane transporters, exist in a variety of normal tissues and play important roles in the disposition of various drugs. The present study seeks to clarify the contribution of P glycoprotein and/or Mrp2 to the disposition of azithromycin in rats. The disappearance of azithromycin from plasma after intravenous administration was significantly delayed in rats treated with intravenous injection of cyclosporine, a...

  10. Crystallization Kinetics within a Generic Modelling Framework

    DEFF Research Database (Denmark)

    Meisler, Kresten Troelstrup; von Solms, Nicolas; Gernaey, Krist

    2013-01-01

    An existing generic modelling framework has been expanded with tools for kinetic model analysis. The analysis of kinetics is carried out within the framework where kinetic constitutive models are collected, analysed and utilized for the simulation of crystallization operations. A modelling...... procedure is proposed to gain the information of crystallization operation kinetic model analysis and utilize this for faster evaluation of crystallization operations....

  11. U.S. weapons-usable plutonium disposition policy: Implementation of the MOX fuel option

    Energy Technology Data Exchange (ETDEWEB)

    Woods, A.L. [ed.] [Amarillo National Resource Center for Plutonium, TX (United States); Gonzalez, V.L. [Texas A and M Univ., College Station, TX (United States). Dept. of Political Science

    1998-10-01

    A comprehensive case study was conducted on the policy problem of disposing of US weapons-grade plutonium, which has been declared surplus to strategic defense needs. Specifically, implementation of the mixed-oxide fuel disposition option was examined in the context of national and international nonproliferation policy, and in contrast to US plutonium policy. The study reveals numerous difficulties in achieving effective implementation of the mixed-oxide fuel option including unresolved licensing and regulatory issues, technological uncertainties, public opposition, potentially conflicting federal policies, and the need for international assurances of reciprocal plutonium disposition activities. It is believed that these difficulties can be resolved in time so that the implementation of the mixed-oxide fuel option can eventually be effective in accomplishing its policy objective.

  12. Induction of Drug Transporters Alters Disposition of Risperidone - A Study in Mice

    Directory of Open Access Journals (Sweden)

    David Holthoewer

    2010-06-01

    Full Text Available Pharmacokinetic interactions, e.g. modulation of drug transporters like P-glycoprotein at the blood-brain barrier, can be a reason for treatment non-response. This study focuses on the influence of induction of drug transporters on the disposition of the antipsychotic drugs risperidone and 9-hydroxyrisperidone. Brain and serum concentrations of risperidone and its active metabolite 9-hydroxyrisperidone, which are known P-glycoprotein substrates, were measured after drug transporter induction with rifampicin, dexamethasone or 5-pregnene-3beta-ol-20-on-16alpha-carbonitrile using high performance liquid chromatography. Disposition of risperidone and 9-hydroxyrisperidone was dramatically decreased in mouse brain and serum after drug transporter induction. The metabolism of risperidone was also affected.

  13. Using Performance Assessment Model in Physics Laboratory to Increase Students’ Critical Thinking Disposition

    Science.gov (United States)

    Emiliannur, E.; Hamidah, I.; Zainul, A.; Wulan, A. R.

    2017-09-01

    Performance Assessment Model (PAM) has been developed to represent the physics concepts which able to be devided into five experiments: 1) acceleration due to gravity; 2) Hooke’s law; 3) simple harmonic motion; 4) work-energy concepts; and 5) the law of momentum conservation. The aim of this study was to determine the contribution of PAM in physics laboratory to increase students’ Critical Thinking Disposition (CTD) at senior high school. Subject of the study were 11th grade consist 32 students of a senior high school in Lubuk Sikaping, West Sumatera. The research used one group pretest-postest design. Data was collected through essay test and questionnaire about CTD. Data was analyzed using quantitative way with N-gain value. This study concluded that performance assessmet model effectively increases the N-gain at medium category. It means students’ critical thinking disposition significant increase after implementation of performance assessment model in physics laboratory.

  14. Dispositional self-control: relationships with aerobic capacity and morning surge in blood pressure.

    Science.gov (United States)

    May, Ross W; Seibert, Gregory S; Sanchez-Gonzalez, Marcos A; Fitzgerald, Michael C; Fincham, Frank D

    2017-01-01

    The psychological, behavioral and psychosocial implications of self-control are well established, but relatively little is known about its implications for physical health. This study examined the association between self-control and two important indicators of cardiovascular risk: morning blood pressure surge (MBPS) and maximum oxygen consumption (VO 2max ). Undergraduate students (N = 78) completed a measure of dispositional self-control (Brief Self-Control Scale), participated in a 24-h ambulatory assessment of heart rate (HR) and blood pressure (BP), and completed the YMCA Cycle Ergometer Submaximal Test. Regression analyzes yielded a significant positive relationship between self-control and VO 2max . Results also indicated a significant negative association between self-control and MBPS, independent of average 24-h blood pressure and VO 2max scores. These findings expand our understanding of the relationship between dispositional self-control and MBPS. Study limitations and directions for future research are discussed.

  15. Disposition of Charges, Out-of-Home Mental Health Treatment, and Juvenile Justice Recidivism.

    Science.gov (United States)

    Robst, John

    2017-08-01

    This study examined whether the disposition of juvenile justice encounters among youth with severe emotional disturbance was associated with the likelihood of recidivism. Court dispositions, such as probation and diversion, as well as Medicaid-funded out-of-home mental health treatment, were compared. Data sources included the Florida Department of Juvenile Justice and Medicaid claims data. Youth receiving probation had the highest recidivism rates. Among youth in out-of-home treatment, those receiving treatment in foster care services had the lowest recidivism rates. Youth placed into a diversion program were less likely to be re-arrested for a felony, whereas youth receiving inpatient psychiatric services were less likely to be re-arrested for a misdemeanor. Mental health treatment may reduce the likelihood of youth continuing on increasing criminal trajectories.

  16. Understanding Libertarian Morality: The Psychological Dispositions of Self-Identified Libertarians

    Science.gov (United States)

    Iyer, Ravi; Koleva, Spassena; Graham, Jesse; Ditto, Peter; Haidt, Jonathan

    2012-01-01

    Libertarians are an increasingly prominent ideological group in U.S. politics, yet they have been largely unstudied. Across 16 measures in a large web-based sample that included 11,994 self-identified libertarians, we sought to understand the moral and psychological characteristics of self-described libertarians. Based on an intuitionist view of moral judgment, we focused on the underlying affective and cognitive dispositions that accompany this unique worldview. Compared to self-identified liberals and conservatives, libertarians showed 1) stronger endorsement of individual liberty as their foremost guiding principle, and weaker endorsement of all other moral principles; 2) a relatively cerebral as opposed to emotional cognitive style; and 3) lower interdependence and social relatedness. As predicted by intuitionist theories concerning the origins of moral reasoning, libertarian values showed convergent relationships with libertarian emotional dispositions and social preferences. Our findings add to a growing recognition of the role of personality differences in the organization of political attitudes. PMID:22927928

  17. Disposition of PUREX facility tanks D5 and E6 uranium and plutonium solutions. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Harty, D.P.

    1993-12-01

    Approximately 9 kilograms of plutonium and 5 metric tons of uranium in a 1 molar nitric acid solution are being stored in two PUREX facility vessels, tanks D5 and E6. The plutonium was accumulated during cleanup activities of the plutonium product area of the PUREX facility. Personnel at PUREX recently completed a formal presentation to the Surplus Materials Peer Panel (SMPP) regarding disposition of the material currently in these tanks. The peer panel is a group of complex-wide experts who have been chartered by EM-64 (Office of Site and Facility Transfer) to provide a third party independent review of disposition decisions. The information presented to the peer panel is provided in the first section of this report. The panel was generally receptive to the information provided at that time and the recommendations which were identified.

  18. Effects of continuity of care and patient dispositional factors on the physician-patient relationship.

    Science.gov (United States)

    Noyes, Russell; Kukoyi, Oladipo A; Longley, Susan L; Langbehn, Douglas R; Stuart, Scott P

    2011-08-01

    We developed a questionnaire to examine the influence of physician and patient variables on the quality of the physician-patient relationship. More than 300 family medicine patients completed self-report measures of the physician-patient relationship and variables likely to influence it. The quality of relationship was related to continuity of physician care (having a primary physician, duration of that relationship, and frequency of visits) and to patient dispositional variables (neuroticism, positive and negative affectivity) but not to demographic variables. The regression model included having a primary physician, duration of relationship with that physician, and positive affectivity. Relationship quality was, in turn, associated with outcomes (adherence to care, treatment response, satisfaction with care, and commitment to physician). The quality of physician-patient relationship is influenced by physician continuity and patient dispositional variables. Better understanding of these may contribute to the therapeutic potential of this important relationship.

  19. Zen meditation and ABC relaxation theory: an exploration of relaxation states, beliefs, dispositions, and motivations.

    Science.gov (United States)

    Gillani, N B; Smith, J C

    2001-06-01

    This study is an attempt to rigorously map the psychological effects of Zen meditation among experienced practitioners. Fifty-nine Zen meditators with at least six years of experience practiced an hour of traditional Zazen seated meditation. A control group of 24 college students spent 60 min silently reading popular magazines. Before relaxation, all participants took the Smith Relaxation States Inventory (SRSI), the Smith Relaxation Dispositions/Motivations Inventory (SRD/MI), and the Smith Relaxation Beliefs Inventory (SRBI). After practice, participants again took the SRSI. Analyses revealed that meditators are less likely to believe in God, more likely to believe in Inner Wisdom, and more likely to display the relaxation dispositions Mental Quiet, Mental Relaxation, and Timeless/Boundless/Infinite. Pre- and postsession analyses revealed that meditators showed greater increments in the relaxation states Mental Quiet, Love and Thankfulness, and Prayerfulness, as well as reduced Worry. Results support Smith's ABC Relaxation Theory.

  20. DOE Plutonium Disposition Study: Pu consumption in ALWRs. Volume 1, Final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-15

    The Department of Energy (DOE) has contracted with Asea Brown Boveri-Combustion Engineering (ABB-CE) to provide information on the capability of ABB-CE`s System 80 + Advanced Light Water Reactor (ALWR) to transform, through reactor burnup, 100 metric tonnes (MT) of weapons grade plutonium (Pu) into a form which is not readily useable in weapons. This information is being developed as part of DOE`s Plutonium Disposition Study, initiated by DOE in response to Congressional action. This document, Volume 1, presents a technical description of the various elements of the System 80 + Standard Plant Design upon which the Plutonium Disposition Study was based. The System 80 + Standard Design is fully developed and directly suited to meeting the mission objectives for plutonium disposal. The bass U0{sub 2} plant design is discussed here.