WorldWideScience

Sample records for ved atrieseptumdefekt hos

  1. Trofiske skift og fysiske faktorer i væksten hos Færøske torsk (Gadus morhua) undersøgt ved brug af stabile isotoper

    DEFF Research Database (Denmark)

    Munk-Nielsen, Jens; Christensen, Jens Tang; Grønkjær, P.

    -2010), og 2) ved undersøgelse af stabile isotoper over en periode på 20 år (1991-2010). År med større vækst ringbredde i otolitten, forbindes med optimale betingelser, mens små ringbredder forbindes med ugunstige år. Ændringerne i otolitterne er et konservativt estimat for variation i vækst, og har derfor...... en mindre amplitude i variationen af ringbredde end direkte vækst målinger. Over hele vækstkronologien ses en negativ udvikling i væksten hos torsk, dog afbrudt af kortere perioder med positiv vækst. De stabile isotop prøver udtages fra hele otolitter fra 5 år gamle torsk. Fra protein delen af...... omgivelser torsken har oplevet, især den omgivende temperatur. Karbon signalet fra den uorganiske del af otolitten vil blive sammenlignet med værdierne i protein delen. De stabile isotop-værdier, samt vækst data vil blive analyseret for at se sammenhængen mellem klimaet og væksten hos torsk. Både lokalt, med...

  2. Tryg i Naturen. En undersøgelse af sikkerhedsforholdene ved aktivt friluftsliv i det kystnære område i Danmark med fokus på sikkerhedskulturen hos jollefiskere, havkajakroere og kitesurfere

    DEFF Research Database (Denmark)

    Andkjær, Søren; Arvidsen, Jan

    kystnære områder? • Hvordan er sikkerhedskulturen ved jollefiskeri, havkajakroning og kitesurfing? • Hvilke erfaringer og resultater findes internationalt i forhold til sikkerhed ved aktivt friluftsliv i de kystnære områder? • Hvilke tiltag kan forbedre sikkerheden ved friluftsliv i Danmark i de kystnære...

  3. Idrætsskader hos motionisten III

    DEFF Research Database (Denmark)

    Fredberg, Ulrich; Honoré, Niels; Charles, Morten

    2015-01-01

    Overbelastningsskader er hyppige – også hos børn. Ofte holdes skaden ved lige på grund af en manglende forståelse for det uhensigtsmæssige i det savtakkede genoptræningsforløb, hvor man genoptager belastningen på maksimalt niveau, så snart smerterne er svundet. Behandlingen består ofte i at forkl......Overbelastningsskader er hyppige – også hos børn. Ofte holdes skaden ved lige på grund af en manglende forståelse for det uhensigtsmæssige i det savtakkede genoptræningsforløb, hvor man genoptager belastningen på maksimalt niveau, så snart smerterne er svundet. Behandlingen består ofte i...

  4. Eosinofil keratitis hos en dansk hest

    DEFF Research Database (Denmark)

    Olsen, Emil; Henriksen, Michala de Linde; Andersen, Pia Haubro

    2009-01-01

    Eosinofil keratitis (EK) er en relativt sjælden øjenlidelse hos hest, som især ses i tempererede områder. Klinisk er lidelsen karakteriseret ved én eller multiple corneaulcerationer dækket med hvidt eller gelatinøst proliferativt subepithelialt plaque. Denne casereport, som omhandler en 20-årig...

  5. Hvordan kan sykepleieren lindre tungpusthet hos den lungekreftrammede pasienten?

    OpenAIRE

    Rostad, Synne Marie; Røshol, Karoline

    2015-01-01

    NORSK: Bakgrunn: Lungekreft er den kreftformen som gir størst dødelighet i Norge, og det er forventet en økning i antall nye tilfeller. Symptombyrden hos disse pasientene er høy. Allerede ved diagnosetidspunktet er 10-15% av de med lungekreft rammet av tungpusthet. Erfaringsmessig er det vanskelig for sykepleiren å stå i en situasjon hvor pasienten med lungekreft føler at han blir kvelt. Hensikt: Økt kunnskap og forståelse om hvordan sykepleieren kan lindre åndenød hos den lungrekreftramme...

  6. Samarbejdets natur hos mennesket og andre aber

    DEFF Research Database (Denmark)

    Byrnit, Jill

    2014-01-01

    Omfattende grader af dele-adfærd og samarbejde hos mennesker finder sted overalt på jorden, men det er ikke et menneskeligt særtræk at være generøs og dele. Mange dyrearter deler med artsfæller, skønt måden, der deles på varierer mellem dyrearter. Igennem de sidste 20 år er der foretaget omfatten...... ved, at der implicit i evnen til menneskeligt samarbejde ligger en motivation for at indgå i opgaveløsende relationer og en basal tillidsfuldhed omkring flokmedlemmer, som ikke er en selvfølgelighed for alle flokdyr, men som mennesket har fremavlet hos den tamme hund....

  7. Demodex og andre ektoparasitter hos danske katte

    DEFF Research Database (Denmark)

    Memborg Jensen, Mia C.; Boysen, Lene; Thamsborg, Stig Milan

    2015-01-01

    Raske katte og katte med hudforandringer blev undersøgt for at belyse forekomst og betydning af Demodex. En tredje gruppe af aflivede vild- og tamkatte blev desuden undersøgt for forekomst af andre ektoparasitter. Forskellige diagnostiske teknikker blev anvendt og evalueret i undersøgelsen. I alt...... indgik 176 katte, som blev undersøgt ved hårpluk, hudskrab, tapetest, flotation affæcesprøve, øreskrab samt kæmning af pelsen. Demodex spp. blev fundet hos tre katte, og hos én af disse blev iagttaget klinisk demodicose. Demodex spp. blev ikke påvist i gruppen af raske katte. Den samlede forekomst af...... ektoparasitter hos de aflivede vild-og tamkatte var 57%. Følgende ektoparasitter blev påvist: Ctenocephalidesfelis felis, Otodectes cynotis, Ixodes spp., Felicola subrostrata,Cheyletiella blakei og Demodex spp.. Alle de anvendte diagnostiske teknikker var effektive til påvisningen af forskellige ektoparasitter...

  8. Alvorlige bivirkninger ved p-pillebrug hos teenagere

    DEFF Research Database (Denmark)

    Nylander, Malin Chatarina; Clausen, Helle V

    2014-01-01

    PubMed-search found studies investigating adverse effects of combined oral contraceptive pills (COC) among teenagers. Four studies found a small negative impact of COC on acquisition of bone mineral density. COC is associated with elevated risk of venous thrombotic events (VTE), especially during...... the first year of usage. VTE risk increases with EE dose and progestin of 3rd and 4th generation. There are several difficulties in studying COC use in teenagers: high dropout rates, ethical considerations and many different COC formulas....

  9. Dannelsen af en psykologisk og videnskabelig habitus hos psykologistuderende

    DEFF Research Database (Denmark)

    Feilberg, Casper

    2014-01-01

    fra Merleau-Ponty, Gadamer, Ricoeur, Bion og Habermas. I en fænomenologisk fortolkning af Bourdieus habitusbegreb, fremhæves vanen som central for at forstå en professions opbyggede beredskab til at agere hensigtsmæssigt og professionelt i forhold til faglige problemstillinger; denne habitus angår......Dannelsen af en psykologisk og videnskabelig habitus hos psykologistuderende, Casper Feilberg Afhandlingen er en empirisk undersøgelse af psykologistuderendes tilegnelse af træk ved en psykologisk og videnskabelig habitus ved psykologistudierne på Roskilde Universitet og Aalborg Universitet. Herved...... bidrager afhandlingen til den overordnede diskussion om, hvad målet med og kvalitet i en universitetsuddannelse skal forstås som. Som udgangspunkt for studiet af psykologistuderendes dannelsesprocesser indføres en analytisk distinktion mellem en psykologisk habitus (fænomen orienteret), og en videnskabelig...

  10. Pulmonal fedtemboli hos traumepatient

    DEFF Research Database (Denmark)

    Rudolph, Søren F.; Hansen, Nikolaj Friis; Edström, Birgitte

    2007-01-01

    Pulmonal fedt emboli (PFE) kan ses, når fedt perler udskilles fra fedtholdige væv og emboliserer i den pulmonale mikrovaskulære cirkulation. Tilstanden ses ved frakturer, særligt lukkede frakturer af lange rørknogler, pelvis og costae 1, 2, men også ved massive bløddelsskader 3, 4, ortopædkirurgi......Pulmonal fedt emboli (PFE) kan ses, når fedt perler udskilles fra fedtholdige væv og emboliserer i den pulmonale mikrovaskulære cirkulation. Tilstanden ses ved frakturer, særligt lukkede frakturer af lange rørknogler, pelvis og costae 1, 2, men også ved massive bløddelsskader 3, 4...

  11. Drænbehandling af recidiverende otitis media hos børn

    DEFF Research Database (Denmark)

    Lous, Jørgen; Trankjær, Christina Ryborg; Thomsen, Janus Laust

    2010-01-01

    I et nyligt publiceret Cochrane-review om effekten af indsættelse af trommehindedræn hos børn med recidiverende akut otitis media (RAOM) fandt man kun to studier, som opfyldte inklusionskriterierne. De inkluderede studier påviste en absolut risikoreduktion for at få AOM på 0,34 på seks måneder. Ved...

  12. Hos de uvidende

    DEFF Research Database (Denmark)

    Bertelsen, Pernille Scholdan; Dahms, Mona-Lisa

    2004-01-01

    I artiklen "Hos de ?uvidende? ? om tavs viden og teknologisk forandring i Tanzania? undersøges tavs viden som ressource i de teknologiske forandrings - processer, som finder sted i Tanzanias landdistrikter. Med en teoretisk ramme for viden, teknologisk viden og innovation, arbejdes der i artiklen...

  13. Pressestivhed ved Verikal Belansning

    DEFF Research Database (Denmark)

    Paludan-Withen, Carsten; Marstrand, Jonas

    Dette projekt er udarbejdet som et polyteknisk midtvejsprojekt på Institut for Produktion og Ledelse. Det indgår som en del af EU-projektet Impress [1.], der drejer sig om at bestemme produktionspressers udbøjning under forskellige belastninger. Grundlaget for dette er, at man ved at kende en...

  14. Komorbiditet ved marginal parodontitis

    DEFF Research Database (Denmark)

    Holmstrup, Palle; Damgaard, Christian; Olsen, Ingar

    2017-01-01

    visse lungeinfektioner. Der er i vekslende grad dokumentation for de nævnte sammenhænge især mht. kausalitet, men en række undersøgelser peger på, at parodontalbehandling kan have gunstig effekt på forløbet af iskæmisk hjertesygdom, diabetes, reumatoid arthritis og på risikoen for pneumoni hos særligt...

  15. Preoperativ angst hos barn

    OpenAIRE

    Bjørnå, Synne Ingrid

    2016-01-01

    Master i anestesisykepleie Tittel og problemstilling: Preoperativ angst hos barn. Er skåringsverktøyet modified Yale Preoperative Anxiety Scale- Short Form (mYPAS-SF) egnet til å vurdere barnets angst? Hvor stor andel av barna opplever preoperativ angst? Er det en sammenheng mellom barnets angst og barnets alder, foreldrenes angst, tidligere anestesi og hastegrad for inngrep/undersøkelse? Bakgrunn: Erfaringsmessig er mange barn som skal opereres engstelige. Dette får n...

  16. Mindfullness og stressmestring - en grounded theory studie: MBSR og metodens påvirkning på stressresponsen hos piloter i forsvaret, med kobling til idrettsutøvere

    OpenAIRE

    Andresen, Eline Granne

    2016-01-01

    Hensikten med denne studien var å se på om og hvordan et Mindfullness Based Stress Reduction program hos piloter kunne påvirke individets stressrespons. Dette ble gjort ved hjelp av metodikken og framgangsmåten i grounded theory. 6 piloter (gjennomsnittsalder: 40.5, SD: 12) ble valgt ut. Ved å bruke grounded theory metodologi (Strauss & Corbin, 1998), ble dataene analysert etter flere omganger med kodingsprosedyrer, og benyttet til utvikling av en egen teori. Fire mentale aspek...

  17. Omkommet ved Brand

    DEFF Research Database (Denmark)

    Leth, Peter Mygind

      Afhandlingen består af tre delundersøgelser. Den første undersøgelse er en hypotesegenererende case-only undersøgelse af branddødsfald i hele landet i 1953-57 og 1988-92. I de to perioder omkom henholdsvis136 og 362 personer ved brandulykker. Mange af de omkomne var alkoholpåvirkede eller...

  18. Business information literacy: informasjonskompetanse ved Handelshøyskolen BI

    Directory of Open Access Journals (Sweden)

    Sigrid Gimse

    2010-07-01

    Full Text Available For å bli en informasjonskompetent student innenfor en internasjonal akademisk handelshøgskole, er det spesielle ferdigheter man må opparbeide seg. Det er ikke de samme kravene til hva en må kunne ved Odontologisk fakultet som ved BI, så heller ikke i bibliotekets sfære. De ferdighetene vi er på jakt etter å utvikle hos våre studenter er generiske for handelshøyskoler verden over, men allikevel er begrepet ”Business Information Literacy” et ganske nytt begrep, og som så mye annet hentet fra USA. Vi synes det er et spennende begrep, all den tid det definerer hva som er kravene, utover den enkelte handelshøyskoles sfære. Vi tror at det kommer til å etableres en standard for denne kompetansen i USA snart, men før dette er klart har vi sett på hva begrepet betyr for oss. Det har nemlig ledet oss mot en særegen undervisnings- og bibliotekpedagogikk. Tilføyelsen ”Business” til begrepet informasjonskompetanse kommer selvsagt på toppen av den generelle definisjonen, som vi også ”bekjenner” oss til og prøver å utvikle hos våre studenter og faglige. Begrepet springer ut av BIs fagområder der kravene til ”Business Information Literacy” kan innebære: • Kunne innhente emnespesifikk fag- og forskningslitteratur i relevante bibliografiske kilder • Kunne innhente makroøkonomiske data nasjonalt og internasjonalt • Kunne innhente forbrukerdemografiske data • Kunne innhente data typiske for markedsanalyse • Kunne innhente data innen bedrifts- industri- og bransjeanalyse • Kunne innhente finansielle data • Kunne bruke juridiske kilder • Kunne inkorporere funn i egne oppgaver etter akademisk standard Hva gjør vi for å utvikle disse ferdighetene hos våre studenter? Hvilke tiltak setter vi verk? Hva gjør handelshøyskoler verden over? Mange bibliotek utvikler i dag elæringsmateriale for å kunne nå det store antall studenter. Dette er også underveis hos oss.

  19. Ensamhetsmotivet hos Ivar Arosenius

    OpenAIRE

    Franzén, Niclas

    2010-01-01

    Uppsatsen behandlar ensamhetsmotivet hos konstnären Ivar Arosenius. Ensamhetsbilderna delas in i olika kategorier efter motiv och stämningsläge. Bilderna analyseras sedan med fokus på symbolistiska tendenser, återkommande teman och influenser från andra konstnärer. This paper deals with the solitude motif of the artist Ivar Arosenius. His solitude pictures are divided into different categories according to subject and sentiment. The images are then analyzed with a focus on symbolistic ten...

  20. Motivasjonsfaktorer hos ledere

    OpenAIRE

    Lien, Roger

    2010-01-01

    Bacheloroppgave i organisasjon og ledelse Norsk: Problemstillingen til denne oppgaven var; "Hva er motivasjonsfaktorene til å bli leder og hva er motivasjonsfaktorene til å være leder?". Ønsket var å sammenligne motivasjonsfaktorene man hadde for å bli leder, med motivasjonsfaktorene man har for å være i en lederjobb. Ved å se på forskjellen mellom indre og ytre motivasjonsfaktorer på før og etter man hadde fått seg en ledende stilling. Kvalitativ metode ble brukt, der fem mellomlede...

  1. Helvede hos Dante

    DEFF Research Database (Denmark)

    Pedersen, Else Marie Wiberg

    2012-01-01

    Dante Alighier (1265-1321) skrev sit store digt La Comedia, kendt som Den guddommelige Komedie i 1300-tallets begyndelse, efter at han var forvist fra Firenze. Digtet skildrer en rejse gennem tre riger: Helvede, Renselsesbjerget og Paradis, som hver især beskriver faser i et menneskes vej mod...... større erkendelse og mod frelse. Netop derfor skal læseren ikke standse ved Helved, men foretage hele rejsen. Dantes pointe er, at vejen til Paradis går gennem Helvede, for menneskelivet er qua mennesket selv langtfra fuldkomment. Artiklen her viser, hvordan Dante beskriver ethvert menneskes vanskelige...... livsafgørelser (kriser) ved fra første færd at inddrage læseren i en knusende krisestemning og føre os ned i all helvedes pinsler, før vi føres op gennem rensende selvindsigter og endelig til at se større livsperspektiver. Ifølge Dante er Helvede kun et kritisk begyndelsespunkt, ikke et slutpunkt....

  2. Supervisors interventioner ved parallelprocesser

    DEFF Research Database (Denmark)

    Jacobsen, Claus Haugaard

    2006-01-01

    Artiklen reflekterer over supervisors anvendelse af, holdning til og intervention ved parallelprocesser. Parallelprocesser betegner en række mere eller mindre forskellige fænomener, der alle har til fælles, at en relation eller et tema i det psykoterapeutiske forhold gentages i det supervisoriske...... forhold eller vice versa. Medens fænomenet er relativt velbeskrevet, findes der overraskende få betragtninger over, hvordan supervisor med fordel kan forholde sig hertil. På baggrund af en litteraturanalyse og ikke mindst inddragelse af et casestudie yder artiklen således et savnet bidrag til området og...... dermed også til den psykodynamiske supervisionsteori. En revideret version af en tidligere model for supervisors valg af foci anvendes bl.a. i et forsøg på at operationalisere nogle guidelines eller principper for supervisoriske interventioner, ligesom niveauet for supervisandernes faglige udvikling...

  3. Overholdelse af energikrav ved renovering

    DEFF Research Database (Denmark)

    Gram-Hanssen, Kirsten; Jensen, Jesper Ole; Stensgaard, Anne Gro

    Denne rapport indeholder en kvalitativt baseret undersøgelse af, hvorvidt bygningsreglements energibestemmelser bliver overholdt ved renovering af større bygninger, dvs. etageboliger, institutioner og erhvervsejendomme. Bygningsreglementets bestemmelser omfatter dels faste krav om energieffektivi......Denne rapport indeholder en kvalitativt baseret undersøgelse af, hvorvidt bygningsreglements energibestemmelser bliver overholdt ved renovering af større bygninger, dvs. etageboliger, institutioner og erhvervsejendomme. Bygningsreglementets bestemmelser omfatter dels faste krav om...... energieffektivisering ved udskiftning af komponenter, fx vinduer og kedler, og dels krav om rentable energieffektiviseringer ved renovering af bygningsdele, fx tag, ydervægge og gulv. Undersøgelsen er baseret på anonyme interview med en række af byggeriets organisationer samt rådgivere og udførende. På baggrund af de...... gennemførte interview må det konkluderes, at der kan være problemer med manglende overholdelse af bygningsreglementets bestemmelser. Problemet gælder primært den del, der omhandler renovering af bygningsdele. Her vil det ofte være muligt at argumentere for, at det ikke er rentabelt at renovere op til dagens...

  4. Research-based learning. Koncept for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College Lillebælt

    DEFF Research Database (Denmark)

    Hansen, Birgit Heimann

    2013-01-01

    Hos University College Lillebælt (UCL) er det en klar ambition, at udviklingsprojekter skal involvere studerende. Gennem deltagelse i udviklingsarbejde udvikler de studerende afgørende kompetencer i forhold til at forstå og håndtere de komplekse sammenhænge, de skal indgå i og medvirke til...... udviklingsaktiviteter er dog en forholdsvis ny og endnu ikke organiseret studieaktivitet, og derfor undersøges med projektet Research-based learning : koncept for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College Lillebælt, hvordan studenterdeltagelse i forsknings- og...... udviklingsaktiviteter kan formes og tilrettelægges som fast studieaktivitet og hermed indgå som en planlagt og organiseret del af de studerendes uddannelse. Delrapport I omfatter den for projektet beskrevne teoretiske referenceramme for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College...

  5. Behandlingsmuligheder ved xerostomi og hyposalivation

    DEFF Research Database (Denmark)

    Jensen, Siri Beier; Dynesen, Anja Weirsøe; Pedersen, Anne Marie Lynge

    2011-01-01

    Behandlingsmuligheder ved nedsat spytsekretion og xerostomi For at kunne iværksætte adækvat lindring og behandling af nedsat spytsekretion og xerostomi bør det tilstræbes, at den tilgrundliggende årsag i videst muligt omfang er forsøgt diagnosticeret. I en del tilfælde er det dog ikke muligt at u...

  6. Forbedret diagnostik af osteomyelitis hos børn?

    DEFF Research Database (Denmark)

    Afzelius, Pia; Alstrup, Aage Kristian Olsen; Schønheyder, Henrik Carl

    Osteomyelitis er en alvorlig sygdom. Tidlig diagnose og påbegyndelse af behandlingen er vigtigt for at forhindre sygdomsudviklingen og for at reducere potentielt alvorlige komplikationer. Konventionel røntgenundersøgelse udført tidligt i forløbet kan ikke udelukke akut osteomyelitis. MRI......, knogleskintigrafi og CT er centrale billeddiagnostiske metoder til diagnostik af akut osteomyelitis hos børn. MRI betragtes ofte som værende den bedste billeddannende metode, men er ikke altid tilgængelig og kræver anæstesi af små børn. Knogleskintigrafi påviser osteoblastaktivitet og anses for at være yderst...... sensitiv men er ikke særlig specifik. 18F-fluordeoxyglucose (FDG) PET har måske den højeste diagnostiske nøjagtighed for bekræftelse/udelukkelse af kronisk osteomyelitis sammenlignet med knogleskintigrafi, MRI og leukocytskintigrafi. Imidlertid har de fleste studier kun anvendt 18F-FDG PET ved mistanke om...

  7. Identifiable Data Files - Health Outcomes Survey (HOS)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medicare Health Outcomes Survey (HOS) identifiable data files are comprised of the entire national sample for a given 2-year cohort (including both respondents...

  8. Depresjon etter slag – en undervurdert diagnose? - hvordan kan sykepleiere bidra til å forebygge depresjon hos pasient som har hatt apoplexia cerebri?

    OpenAIRE

    Bye, Terje; Skotte, Kjetil

    2010-01-01

    Oppgaven handler om hvordan sykepleiere kan bidra til å forebygge depresjon hos pasienter som har hatt apoplexia cerebri, en sykdom som for mange endrer livet radikalt. Vi ønsker med oppgaven å sette fokus på helhetlig sykepleie og på at sykepleier kan bidra til å styrke slagpasienters psykiske helse ved å være et medmenneske som tar i bruk sykepleiefaglige teknikker for å skape håp og optimisme. Først har vi kartlagt enkelt sykdomslæren rundt apoplexia cerebri. Deretter definert depresjon, r...

  9. Fejldiagnostik ved vaginal skanning hos en kvinde, der var gravid efter hormonel follikelstimulation

    DEFF Research Database (Denmark)

    Al-Najami, Issam; Salomon, Søren

    2014-01-01

    We present the case of a 21-year-old woman who developed a simultaneous extra- and intrauterine pregnancy after hormonal induction of ovulation. The case shows a delay in the detection, relying on usual measures as vaginal ultrasound scanning, of the ectopic pregnancy resulting in peritonealia...... and an acute laparoscopy. This is a reminder of the increase in the prevalence of heterotopic pregnancies as a result of hormonal induction of ovulation, and indicates that laparoscopy is the gold standard of detecting the cause of abdominal pain including ectopic pregnancy....

  10. Oro-faciale forandringer ved HIV-infeksjon hos pediatriske pasienter

    OpenAIRE

    Jokstad, Even Granli; Framnes, Thomas Jørgen

    2008-01-01

    Vi valgte som utgangspunkt for vår prosjektoppgave å studere oro-faciale forandringer på pasienter med HIV-infeksjon, med spesiell vekt på pediatriske pasienter som gjennomgikk Highly Active Antiretroviral Therapy (HAART) behandling.

  11. Intratekal baclofenbehandling ved svaer spastisk tetraplegi og dystoni hos børn og unge

    DEFF Research Database (Denmark)

    Illum, Niels Ove; Hansen, Flemming Juul; Fischer, Claudia

    2003-01-01

    with baclofen, tizanidine, dantrolene and/or diazepam. Intrathecal baclofen has therefore been applied in a group of young patients. MATERIAL AND METHODS: Eight children and young adults from East Denmark with spasticity and 12 with dystonia aged 3-18 years (median 10.9 years) were tested, operated and treated...

  12. Koronararteriecalciumscore ved hjertecomputertomografi øger den prognostiske information hos udvalgte personer

    DEFF Research Database (Denmark)

    Rasmussen, Thomas; Zacho, Mette; Kourmaeva, Daria

    2011-01-01

    Cardiovascular disease is the leading cause of death in the western countries. Conventional risk evaluation of asymptomatic individuals is unfortunately inaccurate. There is a need for better diagnostic tools to identify persons, who will benefit from intensified preventive treatment. Coronary...... artery calcium score (CACS) measured by multi-slice CT scan contributes significantly to risk stratification especially in persons with intermediate risk assessed by conventional risk analysis. A CACS-guided preventive intervention strategy seems appealing to reduce mortality due to cardiovascular...

  13. Det kliniske forløb ved valproatforgiftning hos en treårig

    DEFF Research Database (Denmark)

    Blicher, Thalia Marie; Vestergaard, Esben Thyssen; Dalhoff, Kim Peder

    2012-01-01

    after accidental intake of 6,000 mg VA. Treatment included activated charcoal. Clinical observation included measurements of blood pressure, cardiac telemetry, and measurements of serum VA and metabolic parameters every 4-6 hrs. The girl was discharged successfully after 72 hrs with her usual dose of VA....

  14. Lovende resultater ved ultralydvejledt anlæggelse af nerveblokade hos børn

    DEFF Research Database (Denmark)

    Lefort, Michèle Reeslev; Henneberg, Steen; Bille, Anders Bastholm

    2011-01-01

    . Furthermore, US has the potential to reduce the rate of complications. This review describes both classic and US guided techniques for the periferal nerve blocks used for pediatric abdominal and thoracic surgery and briefly discusses the advantages and disadvantages of applying US....

  15. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2015-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences b......'s general condition, renal function and treatment logistics....... between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE. The optimal choice of bone-anti-resorptive agent should depend on the patient...

  16. Prognostisk vaerdi af PET og MRS ved evaluering af cerebral status hos børn

    DEFF Research Database (Denmark)

    Borgwardt, Lise; Danielsen, Else Rubaek; Børch, Klaus

    2002-01-01

    We report a case of a 12-week-old previously normal infant with severe brain damage after an episode of asphyxia during an RS-virus infection. Sub-acute MRI was normal, but new functional techniques, PET (positron emission tomography) and MRS (magnetic resonance spectroscopy) were severely abnormal...

  17. Det kliniske forløb ved valproatforgiftning hos en treårig

    DEFF Research Database (Denmark)

    Blicher, Thalia Marie; Vestergaard, Esben Thyssen; Dalhoff, Kim Peder

    2012-01-01

    Valproic acid (VA) is an antiepileptic drug, and frequently prescribed in pediatrics. VA overdose results in central nervous system depression, insufficient respiration, tachycardia, hypotension, hepatotoxicity, and electrolyte derangement. We describe the clinical course of a three year-old girl...

  18. Alkohol og andre stoffer hos bilister. Stor uheldsrisiko ved promillekørsel

    DEFF Research Database (Denmark)

    Bernhoft, Inger Marie

    2011-01-01

    Det omfattende EU-forskningsprogram DRUID (Driving under the Influence of Alcohol, Drugs and Medicines) er netop afsluttet. Institut for Transport på Danmarks Tekniske Universitet og Retskemisk afdeling, Retsmedicinsk Institut på Københavns Universitet var de danske partnere i projektet, hvor der i...

  19. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2014-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences b...

  20. Antibiotikumprofylakse ved tandbehandling hos patienter med hofte- eller knaeledsalloplastik er sjaeldent nødvendig

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Fuursted, Kurt; Holmstrup, Palle

    2010-01-01

    A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis...... are generally more prone to develop periprosthetic infections it can be considered in these cases to give prophylactic antibiotics before more extensive dental treatments....

  1. Brug af nervestimulator ved anlaeggelse af nervus ischiadicus-blokade hos en crusamputeret patient

    DEFF Research Database (Denmark)

    Heiring, Christian; Kristensen, Billy B

    2008-01-01

    We present a case of a sciatic nerve block performed with the nerve stimulation technique. This technique is normally not used in amputees because detection of a motor response to an electrical stimulation is impossible. In our patient the stimulation provoked a phantom sensation of movement...

  2. Primært gastrointestinale symptomer ved malaria hos flygtningebørn

    DEFF Research Database (Denmark)

    St-Martin, Gry; Thusgaard, Mikkel; Simonsen, Hanne Marie

    2009-01-01

    We present three cases of malaria in refugee children newly arrived from Sub-saharan Africa. Only one of the three children had fever and all had high parasite loads (2,5-14% parasitemia). Malaria is an important differential diagnosis in refugees from endemic areas, regardless of whether...

  3. Lupin og cikorie gavner tarmsundhed hos slagtesvin

    DEFF Research Database (Denmark)

    Jensen, Annette Nygaard; Baggesen, Dorte Lau; Mølbak, Lars

    2011-01-01

    Ved at fodre slagtesvin med 25 procent blå lupin i stedet for standard-foder i blot én uge inden slagtning, kan man tilsyneladende reducere antallet af campylobacter i svinenes gødning......Ved at fodre slagtesvin med 25 procent blå lupin i stedet for standard-foder i blot én uge inden slagtning, kan man tilsyneladende reducere antallet af campylobacter i svinenes gødning...

  4. Zoo handlede helt korrekt ved at aflive Marius

    DEFF Research Database (Denmark)

    Sabir, Fatima

    2014-01-01

    Det syntes rimeligt at konkludere, at Zoo har handlet helt korrekt og etisk forsvarligt ved aflivningen af giraffen.......Det syntes rimeligt at konkludere, at Zoo har handlet helt korrekt og etisk forsvarligt ved aflivningen af giraffen....

  5. Postoperativ kvalme hos cystektomi-opererede patienter

    DEFF Research Database (Denmark)

    Thomsen, L; Kisbye, B; Delmar, Charlotte

    2003-01-01

    Formålet med projektet har været at undersøge og beskrive den foreliggende sygeplejefaglige dokumentation vedrørende postoperativ kvalme hos cystektomi-opererede patienter. I rapporten påpeges de konsekvenser det kan have for den kliniske praksis, hvis der er mangelfuld dokumentation. Desuden giv...

  6. Dyremodeller for psykiatriske sygdomme - om betydningen af homologe og analoge træk ved hjernens udvikling

    DEFF Research Database (Denmark)

    Alstrup, Aage Kristian Olsen

    Mus og rotter er de typiske forsøgsdyr, som bruges til udforskning af menneskets psykiatriske sygdomme, hvilket skyldes primaternes nære fylogenetiske slægtskab med gnaverne. Ind imellem bliver også andre dyr brugt som modeller, blandt andet bananfluer og flere andre hvirvelløse dyr. Posteren vil...... redegøre for betydningen af homologe og analoge træk ved nervesystemet, når der udvælges det rette forsøgsdyr. De senere års forskning synes nemlig at vise, at hjernen og nervesystemet hos alle de bilaterale dyrerækker snarere er homologe end analoge, idet vi har en række næsten identiske gener, der styrer...

  7. Bio-Matematik ved Roskilde Universitet

    DEFF Research Database (Denmark)

    Ottesen, Johnny T.

    2010-01-01

    Ved Institut for Natur, Systemer og Modeller ved Roskilde Universitet finder man en velkonsolideret gruppe af forskere, BioMath-gruppen, der beskæftiger sig med Bio-Matematik og Bio-Medicinsk Modellering. Faktisk startede BioMath-gruppen på det tidligere Institut for Studiet af Matematik og Fysik......-trivielle eksperimenter, kan tjekke om tanker og hypoteser holder og er konsistente samt kan benyttes til at konstruere nye diagnosticerings- og behandlingstilbud, gør at de nævnte metaaspekter er ikke-trivielle aspekter og illustrerer samtidig modelleringslandskabets komplekse moras.   I artiklen forsøger vi...

  8. Omkostningseffektivitet ved hypertensionsbehandling med Losartan i Danmark

    DEFF Research Database (Denmark)

    Keiding, Hans; Hildebrandt, Per; Burke, Thomas

    2006-01-01

    Formålet med denne analyse var set såvel fra samfundets som fra det danske sundhedsvæsens perspektiv at evaluere omkostningseffektiviteten af losartan sammenlignet med atenolol ved behandling af hypertension, baseret på Losartan Intervention For Endpoint (LIFE)-undersøgelsens data Udgivelsesdato...

  9. Digitale leverancer ved aflevering af byggeri

    DEFF Research Database (Denmark)

    Bertelsen, Niels Haldor; Sørensen, Nils Lykke; Shaukat, Fatima

    Udviklingen af det digitale byggeri i Danmark har haft meget fokus på klassifikation, fælles standarder og digitale værktøjer, som skal understøtte en centralt styret bygningsmodel. Der er ved at ske et paradigmeskift, hvor den praktiske anvendelse af IKT i de enkelte faggrupper er mere i centrum...

  10. Moms ved samhandel mellem interesseforbundne parter

    DEFF Research Database (Denmark)

    Jensen, Dennis Ramsdahl

    2004-01-01

    Interesseforbundne parter kan efter omstændighederne udnytte momssystemets fradragsmekanisme ved at fastsætte prisen for indbyrdes samhandel til et niveau, der ligger under leverancernes kostpris. Spørgsmålet er, om afgiftsmyndighederne har mulighed for at gribe korrigerende ind overfor sådanne t...

  11. Årsager til luftvejsinfektioner hos kalve

    DEFF Research Database (Denmark)

    Sloth, Karen Helle; Fisker, Irene; Larsen, Lars Erik

    2008-01-01

    Coronavirus gav anledning til flest antistofstigninger hos nyindsatte kalve i tre ud af fire slagtekalvebesætninger i en mindre undersøgelse gennemført i et Dansk Kvæg projekt. I en af besætningerne var der desuden tydelig reaktion mod andre infektioner. Der blev undersøgt for antistoffer mod cor...... coronavirus, BRSV, parainfluenzavirus (P1-2) og Salmonelle dublin....

  12. Årsager til luftvejsinfektioner hos kalve

    DEFF Research Database (Denmark)

    Sloth, Karen Helle; Fisker, Irene; Larsen, Lars Erik

    2008-01-01

    Coronavirus gav anledning til flest antistofstigninger hos nyindsatte kalve i tre ud af fire slagtekalvebesætninger i en mindre undersøgelse gennemført i et Dansk Kvæg projekt. I en af besætningerne var der desuden tydelig reaktion mod andre infektioner. Der blev undersøgt for antistoffer mod...... coronavirus, BRSV, parainfluenzavirus (P1-2) og Salmonelle dublin....

  13. Tuegravpladserne ved Grøntoft

    DEFF Research Database (Denmark)

    Rindel, Per Ole

    2015-01-01

    Ved Grøntoft er i 1966-1970 udgravet to overpløjede tuegravpladser nær en bebyggelse fra ældre og tidlig yngre førromersk jernalder. Gravpladserne har en indbyrdes afstand på 150 m og forbindes af et hulbælte. Tuegravplads (”L”) synes kun at omfatte fire tuegrave og i alt 18 brandgrave, hvoraf de...

  14. Effekter ved udlicitering af offentlige opgaver

    DEFF Research Database (Denmark)

    Petersen, Ole Helby; Hjelmar, Ulf; Vrangbæk, Karsten

    2014-01-01

    Denne rapport præsenterer resultaterne af en systematisk forskningsoversigt over studier af effekter af udlicitering publiceret i perioden 2011-2014. Forskningsoversigten opdaterer en AKF-rapport fra 2011, som gennemgik publicerede undersøgelser af effekter ved udlicitering i perioden 2000-2011 (......-2014. Indsamlingen og vurderingen af studier er afsluttet d. 27. oktober 2014, hvilket betyder, at studier udgivet efter denne dato ikke indgår i forskningsoversigten....

  15. Musikterapi til reduktion af agitation hos personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Stige, Brynjulf

    2015-01-01

    Urolig adfærd hos demensramte på plejehjem kan defineres og måles med fagbegrebet agitation. Agitation har alvorlige konsekvenser for de berørte og kan føre til fald i livskvalitet og øget medicinering hos personer med svær demens, og kan ligeledes føre til udbrændthed hos omsorgsgivere. Agitation....... The concept agitation is used professionally to define and measure disturbing behaviours in people with severe dementia. The causes are multiple and include factors in the psychosocial environment, which suggests that treatment should be holistic and interdisciplinary and not limited to symptom management...

  16. Hvad er fantastisk ved HBO-serien Game of Thrones?

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2013-01-01

    Blogindlæg på videnskab.dk, kaldt "Hvad er fantastisk ved HBO-serien Game of Thrones?" om HBO tv-serien Game of Thrones......Blogindlæg på videnskab.dk, kaldt "Hvad er fantastisk ved HBO-serien Game of Thrones?" om HBO tv-serien Game of Thrones...

  17. Konstruktionsforberedelse hos Kværner

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Radmer, Jim

    1997-01-01

    Konstruktionsforberedelse kan parallelt til produktionsforberedelse opfattes som opbygning af beredskab og "iscenesættelse" før det egentlige konstruktionsarbejde gennemføres. Der eksisterer allerede i praksis mange måder til opnåelse af større konstruktionsforberedelsesgrad. Toyota anvender....... For virksomheden Kværner Ships Equipment i Göteborg er der opbygget og implementeret en produktmodel ved anvendelse af et moderne CAD og PDM (Product Data Management) system, der danner grundlag for effektiv variantkonstruktion af lugeafdækninger. Virksomhedens know-how opsamles i en produktmodel, hvis kerne er en...

  18. Læring i praksis. Tilrettelegging for å fremme refleksjonskompetanse og læringsutbytte hos studenter i praksis. Erfaringer fra en pilotstudie.

    Directory of Open Access Journals (Sweden)

    Kari Høium

    2009-02-01

    Full Text Available Studien belyser erfaringer med en tilpasset veiledningsmodell i gruppe, for å styrke profesjonell kompetanse hos vernepleiestudenter i praksis. Intervensjonen er gjennomført i forhold til 32 bachelorstudenter fra tre ulike kull. Den tar utgangspunkt i en obligatorisk veiledningsgruppe som foregår inne på høgskolen, midtveis i en av deres praksisperioder. Hovedmålsettingen var å se i hvilken grad veiledningsmodellen bidro til utbytte og læringseffekt i forhold til målsetting for praksisperioden. Et annet mål med studien har vært å skaffe erfaringer med hvordan refleksjon og kritisk tenkning kan læres gjennom praktisk student veiledning. Resultater fra undersøkelsen viste at den tilpassede veiledningsmodellen som her ble benyttet, bidro til å fremme refleksjonskompetanse og læringsutbytte hos studentene. Dette gir grunnlag for videre optimisme med tanke på å styrke vernepleiestudentenes læring og profesjonelle kompetanse. Betydningen forsterkes ved at refleksjonskompetanse fremheves som en sentral kvalitetsvariabel, både fra myndighetene og fra fagfeltet. En videre utfordring vil være å raffinere modellen ytterligere med tanke på utprøving og tilpasset implementering gjennom ulike praksisperioder i studiet.

  19. Laparoskopi kan anvendes ved behandlingen af atypiske lyskenære hernier hos børn

    DEFF Research Database (Denmark)

    Bach, Søren Michelsen; Friis-Andersen, Hans

    2015-01-01

    a femoral hernia. All three had previously undergone negative open exploration. We argue that negative open exploration should be followed by diagnostic laparoscopy and herniotomy in the same procedure and that inguinal herniotomy in children should be performed in departments with expertise in laparoscopy....

  20. Normal D-dimer ved dyb venøs trombose i en overekstremitet hos to patienter med pacemaker

    DEFF Research Database (Denmark)

    Byrne, Christina; Abdulla, Jawdat; Christensen, Jan Kim

    2015-01-01

    Danish guidelines recommend the use of D-dimer to exclude deep venous thrombosis (DVT) in the lower extremities. However, guidelines are lacking for DVT in the upper extremities. We describe two young women with transvenous pacemaker electrodes and symptomatic DVT in related veins. Despite a normal...

  1. Kan kontakt- og opmaerksomhedsforstyrrelser hos småbørn opdages ved sundhedsplejerskernes BOEL-prøve?

    DEFF Research Database (Denmark)

    Jakobsen, Alexandra N; Skovgaard, Anne Mette; Lichtenberg, Anne

    2007-01-01

    a standardised test, BOEL, is performed to screen for hearing loss plus social communication and attention disturbances. METHOD: The predictive value of abnormal reactions at the BOEL test at 8-10 months of age was investigated in a subpopulation of 211 children from the CCCC 2000. Predictions were calculated...

  2. Normal D-dimer ved dyb venøs trombose i en overekstremitet hos to patienter med pacemaker

    DEFF Research Database (Denmark)

    Byrne, Christina; Abdulla, Jawdat; Christensen, Jan Kim

    2015-01-01

    D-dimer, DVT was verified by colour Doppler ultrasound in both cases. The guidelines of American College of Chest Physicians recommend initial evaluation using colour Doppler ultrasound as front-line examination. Accordingly, we suggest a similar revision of Danish guidelines incorporating upper...

  3. Normal D-dimer ved dyb venøs trombose i en overekstremitet hos to patienter med pacemaker

    DEFF Research Database (Denmark)

    Byrne, Christina; Abdulla, Jawdat; Christensen, Jan Kim

    2015-01-01

    Danish guidelines recommend the use of D-dimer to exclude deep venous thrombosis (DVT) in the lower extremities. However, guidelines are lacking for DVT in the upper extremities. We describe two young women with transvenous pacemaker electrodes and symptomatic DVT in related veins. Despite a norm...

  4. Laksekalcitonin ved osteoporose. Effekten af intranasal applikation på knoglemineralindhold og frakturhyppighed hos postmenopausale kvinder med manifeste osteoporotiske forandringer

    DEFF Research Database (Denmark)

    Ravn, Pernille

    1993-01-01

    was significantly lower in the women treated with Salcatonin (about one third of that in the non-Salcatonin treated women). In conclusion the results suggest that, compared with calcium alone, Salcatonin given intranasally reduces the rate of fracture by two thirds in elderly women with moderate osteoporosis......The objective was to study the dose-related response of intranasal salmon calcitonin (Salcatonin) on bone mass and bone turnover and the effect of salcatonin on rates of fracture in elderly women with moderate osteoporosis. A total of 208 healthy women aged 68-72 years, who had a bone mineral...... mg calcium daily. In the calcium-(placebo)-treated group the BMC of the spine increased 1%, whereas an increase of 3% was seen in the 200 IU Salcatonin treated group. There was a dose-related response to Salcatonin manifested by an increase in BMC of 1.0%/100 IU. The incidence of new fractures...

  5. Børns gætterier ved nationale test

    Directory of Open Access Journals (Sweden)

    Kristine Kousholt

    2016-03-01

    omkring børnenes gætterier ved de nationale test, og analyserne bidrager med underkategorier af disse gætterier, der samtidig skal sige noget om testenes forskellige betydninger for forskellige børn. Ambitionen er at forstå børnenes deltagelse ved testene som begrundet i de betingelser, der stiller sig for børnene og herunder begrundet i netop testningen selv.

  6. Implementeringsstudie : en studie av lederroller ved implementering av LUS ved Berg skole

    OpenAIRE

    Michalsen, Anne Berit; Owren, Laila

    2010-01-01

    I denne masteroppgaven studerer vi en implementeringsprosess. I 2008-2009 skulle Leseutviklingsskjema (LUS) implementeres ved Berg skole, og vi ble bedt om å følge denne prosessen på nært hold. Vi mener at vi gjennom denne oppgaven gir kunnskap om en implementeringsprosess der en ekstern veileder har en sentral rolle i prosessen. Hvordan skolens ledelse og den eksterne veilederen inntar ulike roller gjennom implementeringen er en sentral del av vår studie. Formålet med oppgaven er dels å b...

  7. Effekten på sangsvane ved etablering af en vindmøllepark ved Overgaard gods

    DEFF Research Database (Denmark)

    Larsen, J. K.; Clausen, P.

    I forbindelse med planerne om at etablere en vindmøllepark ved Overgaard gods ønskes en redegørelse af de mulige konsekvenser for forekomsten af vandfugle. Ved den påtænkte placering kommer vindmølleparken til at støde op til EF-fuglebeskyttelsesområde nr. 15/Ramsar-område nr. 11. Redegørelsen...... for klassificering af et område af international betydning. Med udgangspunkt i sangsvane vurderes den påtænkte vindmøllepark i relation til 1) effekten på antal og fordeling af fugle, dels i Overgaard området som helhed og, dels i EF-fuglebeskyttelses-/Ramsar-området, og 2) risiko for kollisioner. Vindmølleparkens...... grad afhænge af både den lokale og den regionale afgrødesammensætning og -fordeling. Etablering af mølleparken vurderes ikke at ville have nogen negativ effekt på forekomsten af sangsvaner inden for EF-fuglebeskyttelses-/Ramsar-området, da det kun perifert berøres af forstyrrelsesområdet omkring...

  8. Brok hos hest, kvæg og svin

    DEFF Research Database (Denmark)

    Jacobsen, Stine

    Disse noter skal anvendes som tillæg til de udenlandske lærebøger. Noterne er i overvejende grad baseret på KIRURGI III af Michael Hesselholt og på Hospital for Store Husdyrs Standard Operating Procedure for umbilikal herniorrhaphi hos hest. Nyeste videnskabelige litteratur er inddraget, hvor det...

  9. Vitamin D fysiologi og forsyning hos malkekvæg

    DEFF Research Database (Denmark)

    Hymøller, Lone; Jensen, Søren Krogh

    2015-01-01

    Vitamin D, som tilhører gruppen af fedtopløselige vitaminer, har de seneste år været et af de mest omdiskuterede næringsstoffer i både dansk og udenlandsk presse. Dette skyldes, at vitamin D har vist sig at have indflydelse på mange forskellige fysiologiske processer i kroppen lige fra...... kalciumbalance og knoglestyrke til immunforsvarets funktion. Hos malkekvæg betyder dette, at vitamin D potentielt har stor indflydelse på bl.a. risikoen for kælvningsproblemer og mælkefeber hos køer samt dyrenes generelle holdbarhed og sundhed. Gennem de seneste 10 år har forskere på AU Foulum intenst studeret...... vitamin D-forsyningen og -fysiologien hos malkekvæg. Resultaterne af disse undersøgelser har vist, at sommersollys er en meget vigtig kilde til vitamin D hos malkekøer, og der er en lineært stigende effekt på køernes vitamin D-status i blodet, jo længere tid de dagligt opholder sig i sommersolen. Tilskud...

  10. CRYSTAL-STRUCTURE DETERMINATION OF THE MISFIT LAYER COMPOUND (HOS)1.23NBS2

    NARCIS (Netherlands)

    WIEGERS, GA; MEETSMA, A; HAANGE, RJ; DEBOER, JL

    1992-01-01

    Single-crystal X-ray diffraction has shown that (HoS)1.23NbS2 is a misfit layer compound built of alternate double layers of HoS, approximately a {001} slice of NaCl-type HoS, and sandwiches of NbS2 with niobium in trigonal prisms of sulphur like niobium in 2H-NbS2. The unit cell dimensions of the

  11. 3D modellering af residualspændinger ved pulversvejsning

    DEFF Research Database (Denmark)

    Hansen, Jan Langkjær

    1998-01-01

    Der er opbygget en 3D finite element model i et general purpose FEM-program til beregning af henholdsvis temperaturfelter og de heraf inducerede spændinger ved pulversvejsning i 10mm ST37-2 plade.Til verifikation af de termiske felter er der foretaget temperaturmålinger på en serie...

  12. Miljøundersøgelser ved Maarmorilik 1997

    DEFF Research Database (Denmark)

    Johansen, P.; Riget, F.; Asmund, G.

    Produktionen i bly-zink minevirksomheden i Maarmorilik ophørte i 1990. Miljøtilstanden i området er siden blevet undersøgt årligt ved indsamling og analyse for bly og zink i havvand samt lav og dyr fra området. Denne rapport præsenterer resulta-terne af de undersøgelser, som blev udført i 1997. I...... forhold til tidligere år var undersøgelserne i 1997 af mindre omfang, idet nogle elementer i det undersøgelsesprogram, som er planlagt udført efter minens lukning, ikke udføres hvert år. Spredning af bly og zink med støv fra minevirksomheden er undersøgt ved at indsamle og analysere lavarten Cetraria...... nivalis i området ved Maarmorilik. Der blev i 1997 dels indsamlet og analyseret naturligt forekommende lav i området og dels lav, som i 1996 var blevet transplanteret (flyttet) fra en uforurenet lokalitet til flere lokaliteter ved Maarmorilik. Metalkoncentrationerne i det transplanterede lav var i de...

  13. Sætningsundersøgelser ved Klarup omfartsvej

    DEFF Research Database (Denmark)

    Jørgensen, Mogens B.; Jacobsen, Moust

    Denne rapport, der er den tredje vdr. sætningsobservationer i forbindels med bygningen af omfartsveje om Gistrup og Klarup, vedrører undersøgelser omkring station 5100 ved Klarup. Undersøgelserne er udført efter aftale med Amtsvejvæsenet og i samarbejde med det vejgeotekniske firma "Andreasen og...

  14. H1N1 Influenza A hos mennesker og svin

    DEFF Research Database (Denmark)

    Larsen, Lars Erik

    2009-01-01

    Den nye pandemiske influenza A stamme H1N1 er hovedsagelig et nyt virus, som spredes mellem mennesker, men virusset er formodentlig opstået ved blanding af to svineinfluenza-virus og har derfor bibeholdt evnen til at kunne smitte fra mennesker til svin og fra svin til svin. Det er derfor vigtigt...

  15. Sprog hos børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2010-01-01

    Spredningen i sproglige færdigheder hos børn med autisme er enorm. Dette forhold vanskeliggør forskning inden for området, og omvendt bevirker forskningen og de valg – og ikke mindst fravalg – som autismeforskere er nødt til at foretage, at gruppen af børn med autisme kommer til at fremstå mere...

  16. Energi- og miljøvurdering ved renovering

    DEFF Research Database (Denmark)

    Holleris Petersen, E.

    En afprøvning af pc-værktøjet BEAT 2000's viser, at BEAT 2000 er et velegnet værktøj, der umiddelbart kan anvendes til energi- og miljøvurdering af renoveringssager. BEAT 2000 er afprøvet dels på renovering med energibesparende foranstaltninger i form af solfangere, solvægge og ventilationsanlæg...... med varmegenvinding, dels på mere traditionel renovering af små, utidssvarende lejligheder. En udbygning af datagrundlaget, især for alternative energibesparende løsninger og de materialer, der indgår, vil kunne reducere tidsforbruget ved definition af de utraditionelle og usædvanlige bygningsdele......, der optræder ved renovering....

  17. Rør blot ikke ved min Thailands-tur

    DEFF Research Database (Denmark)

    Petersen, Lars Kjerulf

    2010-01-01

    Klimabevidsthed er ved at blive en fast understrøm i danskernes kollektive bevidsthed. Men klimahensyn er dog langt fra lige så selvfølgeligt som hensynet til velfærd eller øget økonomisk vækst. Og hensyn til miljøet er ligefrem et ugyldigt argument i mange sammenhænge. F.eks. udløser det kold af...

  18. Fair values ved første indregning i regnskabet?

    DEFF Research Database (Denmark)

    Thinggaard, Frank; Nilsson, Sven-Arne

    2007-01-01

    Denne artikel fortsætter gennemgangen og vurderingen af argumentationen, i  IASBs  diskussions-rapport (DP) om mulige målegrundlag, der kan benyttes ved første indregning. DP'et peger entydigt på, at aktiver og forpligtelser bør måles til fair values, såfremt disse kan opgøres tilstrækkeligt...

  19. Miljøundersøgelser ved Kvanefjeldet 2001

    DEFF Research Database (Denmark)

    Asmund, G.

    . Vegetationen omkring malmbunker og sten-tip har kun i begrænset omfang taget skade, og ny vegetation var ved at spire op i bunkerne. Tang, blåmusling og fjeldørred er blevet indsamlet i sommeren 2001 og analyseret for grundstofferne Hg SeAs Be V CrMn Fe CoNi Zn Rb Y ZrNbMo Cd Sb Ba Pb Th U samt 'Sjældne...

  20. Læringsmodstand hos børn

    DEFF Research Database (Denmark)

    Broström, Stig

    2017-01-01

    I dette kapitel beskrives dimensioner ved børns læring og med særligt fokus på Illeris’ begreb læringsmodstand. Det tages udgangspunkt i den kulturhistoriske skoles læringsteori med reference til bl.a. Vygotsky og Leontjev. Børn i såvel dagtilbud som skolen vil løbende vise modstand mod læring...

  1. Karpaltunnelsyndrom: Prognostiske og økonomiske forhold ved endoskopisk operation

    DEFF Research Database (Denmark)

    Meldgaard, Anette

    ¬dage som effektmål. Metode: Prospektiv observationel undersøgelse af en fikseret kohorte. Der blev 99 personer der endo¬skopisk skulle opereres for karpaltunnelsyndrom. Ved baseline blev selvudfyldt spørgeskema ved¬rørende fysiske, psykiske og sociale forhold i relation til deres håndproblemer indsamlet...... operation. Effekten beregnedes som et vægtet gennemsnit af forskellen i antal post-operative sygedage estimeret i randomiserede kliniske undersøgelser af endoskopisk operation versus åben operation. Resultater: Den gennemsnitlige funktionsscore faldt fra 2,3 til 1,4 postoperativt (SD 0,8) og den gen...... % C.L. 1,1-12)) og følelsen af, at det er ens egen skyld at have fået håndproblemer (OR: 1,2 (95 % C.L. 1,01-1,5)) var prognostiske faktorer for over 21 post¬opera-tive sygedage. Dog var jobskifte overvejelser ikke længere signifikant ved en samlet analyse af dis¬se variabler. Med en ressourceindsats...

  2. eSundhedskompetence og brugsmønstre af eksisterende e-sundhedstilbud hos ambulante medicinske patienter med kroniske sygdomme-spørgeskemaundersøgelse

    DEFF Research Database (Denmark)

    Holt, Kamila Beata Adellund

    2016-01-01

    implementeringen af Sundhedsplatformen som et nyt samlet journalsystem. Et af journalsystemets funktionaliteter er Min Sundhedsplatform, som er en patientadgang, hvor borgeren hjemmefra får adgang til en række personlige data, og bl.a. kan udfylde spørgeskemaer udsendt af hospitalerne mm. I regeringens...... sundhedsudspil fra august 2014 blev det meldt ud, at borgere med kroniske sygdomme, skal inddrages mere i egen behandling, for at opnå en tryg hverdag og bedre sygdomsforløb. Den øgede borgerinddragelse skal bl.a. komme i spil via digitalisering, som indebærer nye telemedicinske løsninger, bedre adgang til egne...... patienternes eSundhedskompetence. Dette er ikke undersøgt tidligere. Målingerne af e-Sundhedskompetence hos patienterne er foretaget ved hjælp af validerede spørgeskemaer som er: eHLQ (eHealth Literacy Questionnaire) og eHLA (eHealth Literacy Assessment) suppleret med otte spørgsmål, som afdækker konkret brug...

  3. Sambandet mellan stress mindset och upplevd stress hos gymnasieungdomar

    OpenAIRE

    Edblad, Patrik

    2016-01-01

    Studien undersökte sambandet mellan stress mindset (individens övertygelser om stress) och upplevd stress hos gymnasieungdomar. 122 deltagare i åldrarna 16-19 år deltog i studien genom att svara på ett elektroniskt formulär. Frågorna bestod av Perceived Stress Scale (PSS-14), som undersökte upplevd stress, och Stress Mindset Measure (SMM), som undersökte deltagarnas mindset om stress. Resultatet visade en signifikant negativ korrelation mellan stress mindset och upplevd stress. Detta gav stöd...

  4. Gir tidlig vurdering og behandling hos spesialist i fysikalsk medisin og rehabilitering reduksjon i langtidsfravær hos sykmeldte med muskel- og skjelettsykdommer?

    Directory of Open Access Journals (Sweden)

    Harald Elvsåshagen

    2010-01-01

    Full Text Available Bakgrunn: De fleste langtidssykmeldte med muskel- og skjelettsykdommer blir utredet, behandlet og fulgt opp av fastlege. Ved lengre tids sykmelding henvises mange fra sin fastlege til spesialist i fysikalsk medisin og rehabilitering for å optimalisere behandlingsopplegget.Formålet med denne studien var å undersøke om henvisning direkte fra NAV til spesialist uten å gå veien om fastlege, medførte redusert antall sykmeldingsdager og mindre bruk av andre trygdeytelser som rehabiliteringspenger, yrkesrettet attføring og uførepensjon.Materiale og metode: I samarbeid med 14 NAV-kontor i Vestfold ble 829 sykmeldte i alder 25-50 år med 8-12 ukers sykmelding for muskel- og skjelettsykdommer randomisert til en intervensjonsgruppe (n=409 og en kontrollgruppe (n=420. Eksklusjonskriterier var manglende arbeidsforhold, revmatiske sykdommer, brudd og leddsykdommer. Intervensjonsgruppen ble undersøkt og behandlet av spesialist i fysikalsk medisin og rehabilitering, Spesialsykehuset for rehabilitering, avd. Stavern. Kontrollgruppen fortsatte behandling hos sin fastlege. Noen av disse pasientene ble henvist til samme poliklinikk eller til annen spesialist på initiativ fra sin fastlege. Data for sykmeldingsdager, uførepensjon, rehabiliteringspenger og attføringspenger ble samlet inn fra NAV-kontorene. De samme parametre ble brukt som endepunkter. Etter to år ble endepunktene analysert. Data ble analysert etter "intention to treat"- prinsippet.Resultater: I intervensjonsgruppen var gjennomsnittlig antall sykmeldingsdager 138 dager (SD 86,2 mot 147 dager (SD 88,0 i kontrollgruppen, en forskjell på ni sykmeldingsdager. Forskjellen er ikke statistisk signifikant (p=0,163. Det var heller ikke statistisk signifikant forskjell i forbruket av yrkesrettet attføring og rehabiliteringspenger mellom intervensjonsgruppen og behandlingsgruppen.Konklusjon: Henvisning til spesialist i fysikalsk medisin og rehabilitering direkte fra NAV etter 8-12 ukers sykmelding

  5. Bør leger ha reservasjonsrett ved assistert befruktning?

    Directory of Open Access Journals (Sweden)

    Morten Magelssen

    2011-10-01

    Full Text Available Omfanget av helsepersonells reservasjonsrett har nylig vært gjenstand for debatt i Norge. Vi spør om leger bør ha reservasjonsrett ved utførelse og henvisning til assistert befruktning, og drøfter argumenter for og imot ved hjelp av et rammeverk med sju kriterier for vurdering av reservasjon. Reservasjonsrettens grunnleggende dilemma er hvordan to viktige hensyn, henholdsvis pasientens rett til behandling og hensynet til helsepersonellets moralske integritet, best kan ivaretas. Det argumenteres for at leger bør ha rett til å reservere seg mot å utføre, assistere ved og henvise til assistert befruktning generelt hvis begrunnelsen er hensynet til befruktede eggs moralske verdi. Videre finner vi at leger også kan ha en moralsk rett til reservasjon mot å utføre, assistere ved og henvise til assistert befruktning for likekjønnede, men da på nærmere spesifiserte vilkår.Nøkkelord: reservasjonsrett, assistert befruktning, samvittighet, moralsk integritetEnglish summary: Should physicians have the right to conscientiously object to assisted reproduction?The extent of the healthcare worker's right to conscientious objection has recently been debated in Norway. This article asks whether physicians should have a right to conscientious objection to the performance of, and referral for, assisted reproduction, and discusses arguments for and against the same, utilizing a framework of seven criteria for the evaluation of conscientious objection. The fundamental dilemma of conscientious objection is how two important considerations can be reconciled: the patient's right to treatment, and the protection of the healthcare worker's moral integrity. It is argued that physicians should have the right to object to performing, assisting with, and referring for assisted reproduction generally when the objection is grounded in the moral value of the embryo. Furthermore, physicians may also have a moral right to object to performing, assisting with, and

  6. Hvilken evidens er der for medikamentel behandling af depression hos børn og unge?

    DEFF Research Database (Denmark)

    Thomsen, Per Hove; Sørensen, Merete Juul

    2007-01-01

    Depression hos børn og unge er relativt hyppigt forekommende og kan have svære konsekvenser. Den specifikke antidepressive behandling kan være psykoterapeutisk eller medikamentel. I artiklen gennemgås på baggrund af systematisk litteratursøgning den videnskabelige evidens for medikamentel...... behandling af depression hos børn og unge med hovedvægten lagt på de mest veldokumenterede medikamenter: selektive serotoningenoptagelseshæmmere....

  7. ”Tvivl, dobbelt ironi og sund fornuft hos Montaigne”

    DEFF Research Database (Denmark)

    Diderichsen, Adam

    2006-01-01

    Det vises, at Montaignes berømte skepticisme og religiøse tolerance er baseret på en bestemt tekstuel strategi, som man ville kunne kalde dobbeltironi, og som består i, at subjektet for en bestemt udtalelse bestandigt underminerer den subjektposition, som det selv taler ud fra. Problemet ved...... at forstå Montaignes forhold til religion er derfor ikke så meget - sådan som det traditionelt er blevet antaget - at fastslå, om hans udsagn om dette emne er ironiske eller alvorligt ment. Problemet er snarere at fastslå, om selve ironien er alvorligt eller ironisk ment....

  8. Water Education ved DTU – en e-læringplatform i Moodle til individualiseret kompetenceopbygning i samfundets vandsektor

    Directory of Open Access Journals (Sweden)

    Erik Arvin

    2010-12-01

    utraditionelle undervisningsbehov. Nogle større virksomheder vil i fremtiden skulle satse mere på salg af integrerede løsninger, f.eks. vand- og spildevandsløsninger for hele byområder. Dette kræver, at der er kompetente personer hos bygherrerne til at drive de fremtidige komplekse systemer. Her kan tilbud om uddannelse af bygherrens personale indgå som en konkurrenceparameter i virksomhedernes tilbud. Og netop her vil et fleksibelt e-læringssystem kunne få stor betydning. Målsætningen for udvikling af e-læringssystemet Water Education ved DTU er at opfylde ovennævnte undervisningsbehov. Projektet er i en udviklingsfase, hvorfor de praktiske erfaringer om udvikling af e-læringsmodulerne og brugernes vurderinger af fordele og ulemper er begrænsede. IT- og Telestyrelsen har medfinansieret projektet og deltaget aktivt i følgegruppemøder.

  9. Forebyggende helbredsundersøgelser af gravide kvinder i Danmark. Anamnesepraksis og samtale om proenatal diagnostik ved tidlig undersøgelse i svangerskabet hos praktiserende loege, på fødestedet og hos jordemoder

    DEFF Research Database (Denmark)

    Lindenskov, Lena; Andersen, A M; Andersen, K V

    1993-01-01

    practitioners, 63% of the doctors at the place of delivery and 86% of the midwives replied. Among the pregnant women, 92% replied from general practice, 84% from hospital outpatient departments and 91% from midwives' centres. The interviews about date of delivery and genetic counselling at early visits...... was employed only on special indications. It was concluded that there was a considerable overlap between the interview about the date of delivery and genetic counselling at early visits in general practice and in hospital outpatient departments and, to some extent, at the midwives' centres. The sharing...

  10. Hyppige samtaler kan måske hjælpe ved svært nedsat adhærens hos belastede patienter med hiv

    DEFF Research Database (Denmark)

    Barfod, Toke Seierøe; Bergstedt, Winnie

    2013-01-01

    This pilot study investigates the feasibility and effect of an intervention based on coaching and directly observed therapy (DOT), aimed at patients who are HIV-positive and have massive adherence problems and treatment failure. Participants were followed six months with coaching, homework and DOT...

  11. Diagnostisk udbytte ved gastrointestinal endoskopi hos børn under et år--en toårs opgørelse

    DEFF Research Database (Denmark)

    Nielsen, R G; Fenger, C; Pedersen, S A

    2001-01-01

    INTRODUCTION: Gastrointestinal endoscopy in children is a well-established procedure. We reviewed our experience of endoscopy in infants below one year of age to evaluate indications, endoscopic findings, histology, and complications. MATERIAL AND METHODS: Twenty-eight infants were studied over a...

  12. Erfaring og kompleksitet - en kvalitativ undersøgelse af betydningsfulde forhold hos sygeplejerskerne ved overflytning af patienter fra intensiv til sengeafdeling

    DEFF Research Database (Denmark)

    Frølund, Christina; Poulsen, Kirsten Beedholm

    2013-01-01

    Aim; To disseminate the findings of a study concerning the conditions of significance for nurses during patient transition from the intensive care unit to the general ward. Background: The transition from the intensive care unit to the general ward can be troublesome for some patients and cause...... with four nurses from an intensive care unit and general ward. As a context for understanding, the interpretation was performed using elected data from the nurses’ working conditions. Results: The extent of the individual nurse’s experience affects her choices in the handover situation and her perception...... relocation stress. Studies on this phenomenon suggest that the nurse handover plays a significant role in how the patients experience their transition. The conditions that affect the nurses’ focus during relocation are however unclear. Methods: A hermeneutic interpretation of four qualitative interviews...

  13. Kan kontakt- og opmaerksomhedsforstyrrelser hos småbørn opdages ved sundhedsplejerskernes BOEL-prøve? Copenhagen County Child Cohort 2000

    DEFF Research Database (Denmark)

    Jakobsen, Alexandra N; Skovgaard, Anne Mette; Lichtenberg, Anne

    2007-01-01

    The prevention of disorders in social communication and attention is hampered by the lack of effective tools to screen in the first year of living. In Denmark public health nurses perform screening of physical and mental health in all infants, and at the age of 8-10 months a standardised test, BOEL...

  14. Kan kontakt- og opmaerksomhedsforstyrrelser hos småbørn opdages ved sundhedsplejerskernes BOEL-prøve? Copenhagen County Child Cohort 2000

    DEFF Research Database (Denmark)

    Jakobsen, Alexandra N; Skovgaard, Anne Mette; Lichtenberg, Anne

    2007-01-01

    The prevention of disorders in social communication and attention is hampered by the lack of effective tools to screen in the first year of living. In Denmark public health nurses perform screening of physical and mental health in all infants, and at the age of 8-10 months a standardised test, BOEL......, is performed to screen for hearing loss plus social communication and attention disturbances....

  15. Mekanisk kredsløbsstøtte ved hjælp af cirkulationspumpe anlagt gennem vena subclavia hos en patient med akut hjertesvigt

    DEFF Research Database (Denmark)

    Hansen, Lars Nikolaj; Fabrin, Anja; Jensen, Marianne Kjær

    2014-01-01

    A 65-year-old female patient suffered biventricular failure due to severe lymphoid myocarditis. Mechanical circulatory support was established with peripheral arterial-venous extracorporeal membrane oxygenation (AV-ECMO). The left ventricle was relieved by subclavian Impella 5.0. AV-ECMO was weaned...... with the use of only Impella 5.0 until the 17th day of use, whereupon Impella was phased out. This case report illustrates the use-fulness of combined peripheral VA-ECMO with subclavian Impella 5.0 with the prospect of single use of the subclavian Impella 5.0 until cardiac recovery thereby avoiding central...

  16. Fair values ved første indregning i regnskabet?

    DEFF Research Database (Denmark)

    Thinggaard, Frank; Nilsson, Sven-Arne

    2007-01-01

    IASB har publiceret en diskussionsrapport, i hvilken mulige målegrundlag, der kan anvendes ved første indregning i regnskabet, bliver afvejet i forhold til hinanden. Rapporten konkluderer, at fair values så vidt muligt bør anvendes, såfremt disse værdier kan opgøres tilstrækkeligt pålideligt. I...... modsat fald skal virksomhederne vælge et målegrundlag som substitut for fair values, der kan opgøres pålideligt. Substituttet skal være mest mulig konsistent med fair values, og anvendes på en måde, som bedst muligt afspejler det, som en måling til fair value sigter efter (the fair value measurement...

  17. Perspektiver ved indførelse af gratis offentlig transport

    DEFF Research Database (Denmark)

    Jespersen, Per Homann; Lohmann-Hansen, Anker; Holmberg, Bengt

    den voksende trafik forstærkes. Der er samfundsøkonomiske fordele at hente ved at flytte en del af bilismen over i offentlig transport. Færre biler reducerer nemlig bilismens negative afledte effekter og dermed også samfundets udgifter til dem. Det er effekter som ulykker, luftforurening, CO2-udslip...... samfundsmæssige og langsigtede konsekvenser af at indføre gratis offentlig transport. Og på denne baggrund vurdere om gratis transport kunne være et velegnet politisk instrument til at imødegå de voksende problemer fra trafikken. Også borgeres holdninger, afvejninger og prioriteringer vil blive inddraget i...

  18. Oprensning af forureningen på depotet ved Høfde 42 ved hjælp af nul-valent jern

    DEFF Research Database (Denmark)

    Fjordbøge, Annika Sidelmann; Kjeldsen, Peter; Petersen, Peter Alfred

    Rapporten beskriver forsøg med nul-valent jern på forurenet vand og sediment fra depotet ved Høfde 42 på Harboøre Tange. Resultaterner viser, at parathion og malathion hurtigt og fuldstændigt bliver omdannet til langt mindre toksiske forbindelser, og endvidere nedbrydes mange af de tilstedeværende...... nedbrydningsprodukter betydeligt. Desuden beskrives oprensningsmetoder med nul-valent jern, herunder ZVI-clay teknologien, der her er identificeret som den bedst måde at anvende nul-valent jern til oprensning af forureningen ved Høfde 42....

  19. Nye endokrine behandlinger forlænger overlevelsen ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Brasso, Klaus; Thomsen, Frederik Birkebæk; Berg, Kasper Drimer

    2013-01-01

    Endokrin behandling af prostatacancer (PCa) har været anvendt i mere end 60 år og har stadig en væsentlig plads i behandlingen af patienter med avanceret PCa. Hos en voksen mand opretholder androgener celleantallet i prostata og undertrykker apoptose. Ophæves den androgene stimulation opnås en...... dobbeltvirkning: hæmning af DNA syntese og proliferation samt aktivering af apoptose. Kastrationsbehandling i form af orkiektomi eller behandling med LHRH agonister/antagonister er standard hos patienter med avanceret PCa, men effekten er tidsbegrænset og såkaldt kastrationsresistent progression af PCa optræder...

  20. A HOS-Based Blind Spectrum Sensing in Noise Uncertainty

    Directory of Open Access Journals (Sweden)

    Agus Subekti

    2015-08-01

    Full Text Available Spectrum sensing for cognitive radio is a challenging task since it has to be able to detect the primary signal at a low signal to noise ratio (SNR. At a low SNR, the variance of noise fluctuates due to noise uncertainty. Detection of the primary signal will be difficult especially for blind spectrum sensing methods that rely on the variance of noise for their threshold setting, such as energy detection. Instead of using the energy difference, we propose a spectrum sensing method based on the distribution difference. When the channel is occupied, the distribution of the received signal, which propagates under a wireless fading channel, will have a non-Gaussian distribution. This will be different from the  Gaussian noise when the channel is vacant. Kurtosis, a higher order statistic (HOS of  the  4th order,  is used as normality test for the test statistic. We measured the detection rate of the proposed method by performing a simulation of the detection process. Our proposed method’s performance proved superior in detecting a real digital TV signal in noise uncertainty.

  1. Hvordan reducerer vi stress hos erhvervsaktive med høretab?

    DEFF Research Database (Denmark)

    Lund, Katja; Rosenstand, Claus Andreas Foss

    2015-01-01

    Stressrelateret sygefravær og dårlig social tilknytning til kolleger og ledelse er virkeligheden for mange danskere med nedsat hørelse. Samtidig er det vanskeligt for virksomhederne at håndtere stress hos gruppen, fordi der mangler indsigt i de udfordringer og sammenhænge, der har betydning for...... Storytelling. 6 erhvervsaktive med høretab deltog i perioden 2013 – 2014. Indledende brugertests indikerer, at dialogværktøjet har po- tentiale som et organisatorisk forståelses- og procesværktøj til reduktion og forebyggelse af stress hos målgruppen....

  2. Hyperbilirubinemi hos nyfødte – et kontroversielt tema. Erfaringer med nye indikasjoner for fototerapi og utskiftningstransfusjon

    Directory of Open Access Journals (Sweden)

    Alf Meberg

    2009-10-01

    Full Text Available  SAMMENDRAGNye indikasjoner for behandling av hyperbilirubinemi hos nyfødte (bilirubinskjema fra Hillingdon sykehus,England ble innført ved Vestfold sentralsykehus primo 1994. Endringene i panoramaet av behandlingstiltak(lysbehandling, utskiftningstransfusjon ble registrert i kohortene av levende fødte ved sykehuset i toårsperioden1994-95 og sammenlignet med foregående treårsperiode 1991-93. Total lysbehandlingsprevalens falt signifikantfra 6,9% av levende fødte i perioden 1991-93 til 5,5% i perioden 1994-95 (p betydelig fall i prevalensen av fullbårne barn som ble lysbehandlet for fysiologisk ikterus, fra 4,3% til 1,6% ihenholdsvis første og siste periode (p steg signifikant fra 2,0% av levende fødte til 3,2% (p økning i prematuritetsinsidensen, som steg fra 4,5% i perioden 1991-93 til 5,9% i perioden 1994-95 (p Andelen premature som ble lysbehandlet steg fra 45,2% i første til 53,1% i siste periode (p av blodgruppeimmuniserte barn som ble lysbehandlet var uforandret i de to periodene (henholdsvis 0,6% og0,7% (p > 0,05. Det var en markert reduksjon i prevalensen av barn som gjennomgikk utskiftningstransfusjon(fra 0,2 til 0,06% henholdsvis i de to periodene (p effekter av lysbehandling til friske fullbårne barn med ikterus, reduseres relativt betydelig med de moderatejusteringer av indikasjonene som er foretatt. Rutineskiftet har også betydd ressurssparing. På landsbasis vil en slikrutineendring medføre at 1000-2000 fullbårne barn hvert år kan unngå lysbehandling. Indikasjonene for fototerapiog utskiftningstransfusjon for hyperbilirubinemi hos nyfødte i Norge må diskuteres på nytt i lys av ny forskningmed tanke på nasjonal konsensus. Kortere liggetider for nyfødte i sykehus etter fødselen gjør det nødvendig medgode rutiner for oppfølging av hyperbilirubinemi utenfor sykehus.Meberg A. Hyperbilirubinemia – a controversial topic. Experiences with new guidelines for phototherapyand exchange transfusion . Nor J

  3. Life and consciousness - The Vedāntic view.

    Science.gov (United States)

    Shanta, Bhakti Niskama

    2015-01-01

    In the past, philosophers, scientists, and even the general opinion, had no problem in accepting the existence of consciousness in the same way as the existence of the physical world. After the advent of Newtonian mechanics, science embraced a complete materialistic conception about reality. Scientists started proposing hypotheses like abiogenesis (origin of first life from accumulation of atoms and molecules) and the Big Bang theory (the explosion theory for explaining the origin of universe). How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from Nothing (as proposed by Stephen Hawking, among others), proves to be dissembling, since the quantum vacuum can hardly be considered a void. In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on Earth is nothing but a mere increment in the complexity of matter - and hence is an outcome of evolution of matter (chemical evolution) following the Big Bang. After the manifestation of life, modern science believed that chemical evolution transformed itself into biological evolution, which then had caused the entire biodiversity on our planet. The ontological view of the organism as a complex machine presumes life as just a chance occurrence, without any inner purpose. This approach in science leaves no room for the subjective aspect of consciousness in its attempt to know the world as the relationships among forces, atoms, and molecules. On the other hand, the Vedāntic view states that the origin of everything material and nonmaterial is sentient and absolute (unconditioned). Thus, sentient life is primitive and reproductive of itself - omne vivum ex vivo - life comes from life. This is the scientifically verified law of experience. Life is essentially cognitive and conscious. And, consciousness, which is fundamental, manifests itself in the gradational forms of all

  4. Life and consciousness – The Vedāntic view

    Science.gov (United States)

    Shanta, Bhakti Niskama

    2015-01-01

    In the past, philosophers, scientists, and even the general opinion, had no problem in accepting the existence of consciousness in the same way as the existence of the physical world. After the advent of Newtonian mechanics, science embraced a complete materialistic conception about reality. Scientists started proposing hypotheses like abiogenesis (origin of first life from accumulation of atoms and molecules) and the Big Bang theory (the explosion theory for explaining the origin of universe). How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from Nothing (as proposed by Stephen Hawking, among others), proves to be dissembling, since the quantum vacuum can hardly be considered a void. In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on Earth is nothing but a mere increment in the complexity of matter — and hence is an outcome of evolution of matter (chemical evolution) following the Big Bang. After the manifestation of life, modern science believed that chemical evolution transformed itself into biological evolution, which then had caused the entire biodiversity on our planet. The ontological view of the organism as a complex machine presumes life as just a chance occurrence, without any inner purpose. This approach in science leaves no room for the subjective aspect of consciousness in its attempt to know the world as the relationships among forces, atoms, and molecules. On the other hand, the Vedāntic view states that the origin of everything material and nonmaterial is sentient and absolute (unconditioned). Thus, sentient life is primitive and reproductive of itself – omne vivum ex vivo – life comes from life. This is the scientifically verified law of experience. Life is essentially cognitive and conscious. And, consciousness, which is fundamental, manifests itself in the gradational forms of all

  5. The Arabidopsis E3 ubiquitin ligase HOS1 negatively regulates CONSTANS abundance in the photoperiodic control of flowering.

    Science.gov (United States)

    Lazaro, Ana; Valverde, Federico; Piñeiro, Manuel; Jarillo, Jose A

    2012-03-01

    The Arabidopsis thaliana early in short days6 (esd6) mutant was isolated in a screen for mutations that accelerate flowering time. Among other developmental alterations, esd6 displays early flowering in both long- and short-day conditions. Fine mapping of the mutation showed that the esd6 phenotype is caused by a lesion in the high expression of osmotically responsive genes1 (HOS1) locus, which encodes a RING finger-containing E3 ubiquitin ligase. The esd6/hos1 mutation causes decreased flowering locus C expression and requires CONSTANS (CO) protein for its early flowering phenotype under long days. Moreover, CO and HOS1 physically interact in vitro and in planta, and HOS1 regulates CO abundance, particularly during the daylight period. Accordingly, hos1 causes a shift in the regular long-day pattern of expression of flowering locus T (FT) transcript, starting to rise 4 h after dawn in the mutant. In addition, HOS1 interacts synergistically with constitutive photomorphogenic1, another regulator of CO protein stability, in the regulation of flowering time. Taken together, these results indicate that HOS1 is involved in the control of CO abundance, ensuring that CO activation of FT occurs only when the light period reaches a certain length and preventing precocious flowering in Arabidopsis.

  6. The Arabidopsis E3 Ubiquitin Ligase HOS1 Negatively Regulates CONSTANS Abundance in the Photoperiodic Control of Flowering[W

    Science.gov (United States)

    Lazaro, Ana; Valverde, Federico; Piñeiro, Manuel; Jarillo, Jose A.

    2012-01-01

    The Arabidopsis thaliana early in short days6 (esd6) mutant was isolated in a screen for mutations that accelerate flowering time. Among other developmental alterations, esd6 displays early flowering in both long- and short-day conditions. Fine mapping of the mutation showed that the esd6 phenotype is caused by a lesion in the HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1) locus, which encodes a RING finger–containing E3 ubiquitin ligase. The esd6/hos1 mutation causes decreased FLOWERING LOCUS C expression and requires CONSTANS (CO) protein for its early flowering phenotype under long days. Moreover, CO and HOS1 physically interact in vitro and in planta, and HOS1 regulates CO abundance, particularly during the daylight period. Accordingly, hos1 causes a shift in the regular long-day pattern of expression of FLOWERING LOCUS T (FT) transcript, starting to rise 4 h after dawn in the mutant. In addition, HOS1 interacts synergistically with CONSTITUTIVE PHOTOMORPHOGENIC1, another regulator of CO protein stability, in the regulation of flowering time. Taken together, these results indicate that HOS1 is involved in the control of CO abundance, ensuring that CO activation of FT occurs only when the light period reaches a certain length and preventing precocious flowering in Arabidopsis. PMID:22408073

  7. Implementering af e-læring ved danske universiteter

    Directory of Open Access Journals (Sweden)

    Birgitte Heiberg

    2005-05-01

    Full Text Available

    Første gang publiceret i UNEV nr. 6: Organisering af e-læring, oktober - december 2005, red. Jørgen Gomme, Birgitte heiberg, Jens Dørup og Ambrosia Hansen. ISSN 1603-5518.

    Lige siden de første computere kom til landet har der været projekter, som tilsigtede at understøtte undervisning og læring ved hjælp af IKT. Understøttelsen har varieret som en bred vifte af forskellige former for medieanvendelse og grader af interaktion. Tilsvarende er diverse former for IKT-støttet undervisning og læring med forskellige betegnelser dukket op: Computer-Based Training (CBT, Computer Assisted Learning (CAL, Computer Supported Collaborative Learning (CSCL, Web-based Learning (WBL, blended learning, online læring, fleksibel læring, fjernundervisning, distribueret og åben uddannelse, m. fl.

  8. Tvivl og utryghed hos patienter med reumatologisk sygdom - oplevelsen af transitionen fra sengeafsnit til eget hjem

    DEFF Research Database (Denmark)

    Twisttmann Bay, Laila; Aagaard, Hanne

    2016-01-01

    Baggrund: Kronisk sygdom kan medføre fysiske begrænsninger på grund af smerter og nedsat bevægelighed, træthed, påvirkning af hverdagslivet og medicinsk behandling med bivirkninger. Dette kan bidrage til tvivl og utryghed hos både ny diagnosticerede patienter og kronisk syge. Det er uklart, hvilk...

  9. Emerging countries’ multinational companies investing in developed countries: at odds with the HOS paradigm?

    Directory of Open Access Journals (Sweden)

    Andreff, Wladimir

    2013-04-01

    Full Text Available The paper analyses the new trend of outward foreign direct investment (FDI by multinational companies from emerging countries, in particular the BRICs, in developed countries to question the applicability of the traditional HOS theoretical framework to this trend. A literature review shows that labour costs do not play any significant role in the first attempts to provide an analytical explanation of this new trend. A HOS equation, amended in order to encompass FDI, is elaborated in order to explain outward FDI from developed to developing and emerging countries based on differences in labour endowment and therefore in wage rates. Step by step, the equation introduces the technological gap, institutions and government policies. Then it is shown that such equation when reversed to explain outward FDI from emerging to developed countries is at odds with the traditional HOS framework. Turning the HOS theory upside down does not help to explain reverse FDI outflows from emerging to developed countries. An alternative approach is called for, in which a labour cost advantage (a lower wage rate than abroad is a home market advantage for emerging countries to invest abroad. A final section provides some empirical examples that labour matters and a lower home wage rate is a decisive comparative advantage for Indian and Chinese multinationals investing in developed countries. Additional evidence shows that the technological gap and the home country’s institutions and government policy matter as well

  10. Intervention rettet mod sproget hos børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2014-01-01

    Sprogniveauet hos børn med autisme er afgørende for deres muligheder for udfoldelse og udvikling, og sproget er et udviklingsområde, der er meget modtageligt for intensiv intervention. Imidlertid modtager danske børn med autisme kun sjældent intensiv intervention rettet mod sproget. De intensive...

  11. Research-based learning: Koncept for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College Lillebælt

    DEFF Research Database (Denmark)

    Hansen, Birgit Heimann

    KONCEPT FOR STUDENTERDELTAGELSE I FORSKNINGS- OG UDVIKLINGSAKTIVITETER VED UNIVERSITY COLLEGE LILLEBÆLT omfatter begrebsdefinering og belysning af grundlaget for fremtidig initiering af studenterdeltagelse ved University College Lillebælt. RESEARCH-BASED LEARNING indgår i University College...

  12. Klinisk retningslinje for opsporing af angst og/eller depression hos indlagte og ambulante patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Strømstad, Grisja Vorre; Stassen, Ingelise Trosborg; Lassen Nielsen, Stine

    2015-01-01

    Formålet med den kliniske retningslinje er, at identificere screeningsredskaber der kan opspore angst og depression hos patienter med KOL, så patienter med angst og/eller depression bliver tilbudt relevant behandling.......Formålet med den kliniske retningslinje er, at identificere screeningsredskaber der kan opspore angst og depression hos patienter med KOL, så patienter med angst og/eller depression bliver tilbudt relevant behandling....

  13. Hvilken evidens er der for behandling af depression hos børn og unge med kognitiv terapi?

    DEFF Research Database (Denmark)

    Sørensen, Merete Juul; Thomsen, Per Hove

    2007-01-01

    Depression hos børn og unge er relativt hyppigt forekommende og kan have svære konsekvenser. Den specifikke antidepressive behandling kan være psykoterapeutisk eller medikamentel. I artiklen gennemgås på baggrund af systematisk litteratursøgning den videnskabelige evidens for effekten af kognitiv...... adfærdsterapi hos børn og unge med depression....

  14. Radiografens brug af Retorisk strategi ved en CT undersøglse

    DEFF Research Database (Denmark)

    Rasmussen, Jonas Værlund

    2012-01-01

    Formålet med denne opgave er at undersøge hvordan radiografen etablerer et tillidsforhold til patienten ved en CT scanning. Radiografens selvfremstilling undersøges i forhold til Ethos begrebet. På baggrund af retorisk analyse og diskussion undersøges det om der kan angives retningslinjer for den...... tillidsvækkende kommunikation. Etableringen af tillid undersøges via et observationsstudie, hvor kommunikationen mellem radiograf og patient analyseres. Studiet viser at radiografen, ved at bruge direkte og indirekte ethos appel, formår at anvende de genkomne topoi i situationen som tillidsskabende elementer....

  15. Akutte dødsfald ved tvangsfastholdelse af svært hyperaktive personer

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Thomsen, Jørgen Lange

    2012-01-01

    må henføres til et syndrom som betegnes excited delirium syndrome (EDS), en akut indsættende tilstand karakteriseret ved en hyperaktiv og voldelig adfærd, næsten overmenneskelig styrke og immunitet for smerte. Obduktion viser ikke forandringer som kan forklare dødsfaldet. Årsagen til EDS er ukendt...

  16. Miljøoptimering af afvaskning ved tryk med vandfortyndbar flexotrykfarve

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Helweg, Christian; Pedersen, Anne Rathmann

    Rapporten beskriver praksis ved afvaskning af vandfortyndbare flexotrykfarver i emballageindustrien og anviser muligheder for indførelse af renere teknologi til reduktion af spildevandsbelastningen. Anbefalingerne omfatter a) udformning af farveværker med henblik på effektiv tømning af farve og e...

  17. Manual for udførelse af triaksialforsøg ved AAU

    DEFF Research Database (Denmark)

    Thøgersen, Lotte

    Kontinuerlige ødometerforsøg er en ny type forsøg udført ved Laboratoriet for Fundering på Aalborg Universitet. Det kontinuerlige ødometerforsøg udføres i et triaxialapparat og med brug af de samme type transducerer, belastningsarrangementer og opsamlingsenheder. Der vil i rapporten beskrives en ...

  18. Nanotubo de carbono-chitosan en células HOS y THP-1 Carbon nanotubes-chitosan in HOS and THP-1 cells

    Directory of Open Access Journals (Sweden)

    John Jairo Castillo León

    2011-04-01

    Full Text Available Introducción: Los nanotubos de carbono (NTC son estructuras nanométricas utilizadas en el tratamiento de enfermedades, principalmente en la entrega de fármacos para terapias en cáncer. Objetivos: Estudiar la internalización de NTC acoplado a quitosan (NTC-Q en células de osteosarcoma humano (HOS y monocitos humanos de leucemia aguda (THP-1. Materiales y métodos: Los NTC solubilizados con quitosan 30% fueron caracterizados espectroscópicamente por UV-Vis, fluorescencia y Raman. Las células HOS y THP-1 fueron tratadas con NTC-Q y se evaluó la internalización por tinción de Giemsa en microscopio de luz y la citotóxicidad utilizando la prueba fluorométrica de Azul de Alamar. Resultados: Los espectros Raman y de fluorescencia mostraron la funcionalización de los NTC con quitosan. Los NTC fueron internalizados por las líneas celulares después de 24 h mostrando una ubicación citoplasmática sin presentar citotóxicidad en ninguna de las células evaluadas. Discusión: Las características presentadas por los NTC-Q les brinda la posibilidad de ser utilizados como transportadores de fármacos. Salud UIS 2011; 43(1: 21-26Introduction: Carbon nanotubes (CNT are nanometer-sized structures used in medicine in the treatment of diseases, mainly in drug delivery in therapies against cancer. Objectives: To Study the internalization of carbon nanotubes modified with chitosan (CNT-CH in human osteosarcom cells (HOS and human monocytes of acute leukemia (THP1. Materials and methods: The CNTs solubilized in chitosan 30% were characterized spectroscopically by UV-Vis, fluorescence and Raman. HOS cells and THP-1 were treated with CNT-CH, the internalization was evaluated by Giemsa staining with light microscopy, and cytotoxicity was determined using Alamar Blue assay. Results: Raman and fluorescence spectra showed the functionalization of the CNT with chitosan. After 24 h the NTC were internalized in the cell lines showing a cytoplasmic location and

  19. HOS cell adhesion on Ti6Al4V surfaces texturized by laser engraving

    Science.gov (United States)

    Sandoval Amador, A.; Carreño Garcia, H.; Escobar Rivero, P.; Peña Ballesteros, D. Y.; Estupiñán Duran, H. A.

    2016-02-01

    The cell adhesion of the implant is determinate by the chemical composition, topography, wettability, surface energy and biocompatibility of the biomaterial. In this work the interaction between human osteosarcoma HOS cells and textured Ti6Al4V surfaces were evaluated. Ti6Al4V surfaces were textured using a CO2 laser in order to obtain circular spots on the surfaces. Test surfaces were uncoated (C1) used as a control surface, and surfaces with points obtained by laser engraving, with 1mm spacing (C2) and 0.5mm (C3). The HOS cells were cultured in RPMI-1640 medium with 10% fetal bovine serum and 1% antibiotics. No cells toxicity after one month incubation time occurred. The increased cell adhesion and cell spreading was observed after 1, 3 and 5 days without significant differences between the sample surfaces (C2 and C3) and control (uncoated) at the end of the experiment.

  20. HOS cell adhesion on Ti6Al4V ELI texturized by CO2 laser

    Science.gov (United States)

    Sandoval-Amador, A.; Bayona–Alvarez, Y. M.; Carreño Garcia, H.; Escobar-Rivero, P.; Y Peña-Ballesteros, D.

    2017-12-01

    In this work, the response of HOS cells on Ti6Al4V ELI textured surfaces by a CO2 laser was evaluated. The test surfaces were; smooth Ti6Al4V, used as the control, and four textured surfaces with linear geometry. These four surfaces had different separation distances between textured lines, D1 (1000 microns), D2 (750 microns), D3 (500 microns) and D4 (250 microns). Toxicity of textured surfaces was assessed by MTT and the cellular adhesion test was performed using HOS ATCC CRL 1543 line cells. This test was done after 5 days of culture in a RPMI 1640 medium supplemented with 10% fetal bovine serum and 1% antibiotics. The results showed that the linear textures present 23% toxicity after 30 days of incubation, nevertheless, the adhesion tests results are inconclusive in such conditions and therefore the effect of the line separation on the cell adhesion cannot be determined.

  1. Automatic Detection of Pathologies in The Voice by HOS Based Parameters

    Directory of Open Access Journals (Sweden)

    de Leon José

    2001-01-01

    Full Text Available In the current panorama the conclusive identification of a laryngeal pathology relies inevitably on the observation of the vocal folds by means of laryngoscopical techniques. This inspection technique is inconvenient for a number of reasons, such as its high cost, the duration of the inspection, and, above all, the fact that it is an invasive technique. This paper looks into the possibility of measuring the quality of a voice starting from an audio recording. The existing parameters in current literature ("classic parameters" which allow quantifying the quality of a voice have been studied, and the parameters that present better results have been selected. Also, seven new High Order Statistics (HOS based parameters are proposed to parametrize the voice signal. On the other hand, a software package has been developed which carries out the automatic detection of dysfunction in phonation. A success rate of % has been obtained by using both the classic and the HOS based proposed parameters.

  2. Skadelig mutation nedsætter frughtbarheden hos de røde racer

    DEFF Research Database (Denmark)

    Sahana, Goutam; Pedersen, Louise Dybdahl

    2014-01-01

    Igennem flere årtier er mælkeydelsen steget støt hos de danske malkekvægracer, og det er én af årsagerne til, at frugtbarheden fortsat er lav, idet der er en ugunstig sammenhæng mellem mælkeydelse og frugtbarhed (fig. 1). Hidtil har man ment, at den ugunstige sammenhæng skyldtes en negativ energi...

  3. Sammenhengen mellom ADHD-symptomer og eksekutive vansker hos førskolebarn med autismespekterforstyrrelser

    OpenAIRE

    Midtstigen, Endre Martin Blindheim

    2015-01-01

    Forfatter: Endre Blindheim Midtstigen Tittel: Sammenhengen mellom ADHD-symptomer og eksekutive vansker hos førskolebarn med autismespekterforstyrrelser Hovedveileder: Professor Stephen Von Tetzchner, Universitetet i Oslo Biveileder: Pål Surén, PhD, Nasjonalt folkehelseinstitutt Bakgrunn: Barn med autismespekterforstyrrelser (ASF) har ofte eksekutive vansker. Studier antyder at skolebarn som har samforekomst av ASF og ADHD-symptomer (ASF+) har større grad av eksekutive vansker relativt til de ...

  4. The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.

    Directory of Open Access Journals (Sweden)

    Alberto Elías-Villalobos

    2015-08-01

    Full Text Available Morphological changes are critical for host colonisation in plant pathogenic fungi. These changes occur at specific stages of their pathogenic cycle in response to environmental signals and are mediated by transcription factors, which act as master regulators. Histone deacetylases (HDACs play crucial roles in regulating gene expression, for example by locally modulating the accessibility of chromatin to transcriptional regulators. It has been reported that HDACs play important roles in the virulence of plant fungi. However, the specific environment-sensing pathways that control fungal virulence via HDACs remain poorly characterised. Here we address this question using the maize pathogen Ustilago maydis. We find that the HDAC Hos2 is required for the dimorphic switch and pathogenic development in U. maydis. The deletion of hos2 abolishes the cAMP-dependent expression of mating type genes. Moreover, ChIP experiments detect Hos2 binding to the gene bodies of mating-type genes, which increases in proportion to their expression level following cAMP addition. These observations suggest that Hos2 acts as a downstream component of the cAMP-PKA pathway to control the expression of mating-type genes. Interestingly, we found that Clr3, another HDAC present in U. maydis, also contributes to the cAMP-dependent regulation of mating-type gene expression, demonstrating that Hos2 is not the only HDAC involved in this control system. Overall, our results provide new insights into the role of HDACs in fungal phytopathogenesis.

  5. The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.

    Science.gov (United States)

    Elías-Villalobos, Alberto; Fernández-Álvarez, Alfonso; Moreno-Sánchez, Ismael; Helmlinger, Dominique; Ibeas, José I

    2015-08-01

    Morphological changes are critical for host colonisation in plant pathogenic fungi. These changes occur at specific stages of their pathogenic cycle in response to environmental signals and are mediated by transcription factors, which act as master regulators. Histone deacetylases (HDACs) play crucial roles in regulating gene expression, for example by locally modulating the accessibility of chromatin to transcriptional regulators. It has been reported that HDACs play important roles in the virulence of plant fungi. However, the specific environment-sensing pathways that control fungal virulence via HDACs remain poorly characterised. Here we address this question using the maize pathogen Ustilago maydis. We find that the HDAC Hos2 is required for the dimorphic switch and pathogenic development in U. maydis. The deletion of hos2 abolishes the cAMP-dependent expression of mating type genes. Moreover, ChIP experiments detect Hos2 binding to the gene bodies of mating-type genes, which increases in proportion to their expression level following cAMP addition. These observations suggest that Hos2 acts as a downstream component of the cAMP-PKA pathway to control the expression of mating-type genes. Interestingly, we found that Clr3, another HDAC present in U. maydis, also contributes to the cAMP-dependent regulation of mating-type gene expression, demonstrating that Hos2 is not the only HDAC involved in this control system. Overall, our results provide new insights into the role of HDACs in fungal phytopathogenesis.

  6. Research-based learning. Koncept for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College Lillebælt

    DEFF Research Database (Denmark)

    Hansen, Birgit Heimann

    2015-01-01

    Studenterdeltagelse i forsknings- og udviklingsaktiviteter er en forholdsvis ny og endnu ikke organiseret studieaktivitet, og derfor undersøges med projektet RESEARCH-BASED LEARNING: KONCEPT FOR STUDENTERDELTAGELSE I FORSKNINGS- OG UDVIKLINGSAKTIVITETER VED UNIVERSITY COLLEGE LILLEBÆLT, hvordan...... forslag til et koncept for studenterdeltagelse i forsknings- og udviklingsaktiviteter ved University College Lillebælt. Som introduktion til projektet indledes DEN AFSLUTTENDE RAPPORT DEL I med en sammenfatning og perspektivering af projektets resultater. Herefter præsenteres projektets...

  7. Øvrige værnsreglers betydning ved dansk CFC-beskatning

    DEFF Research Database (Denmark)

    Schmidt, Peter Koerver

    2014-01-01

    I artiklen analyseres spørgsmålet om, hvorvidt de forskellige værnsregler i dansk skattelovgivning også skal finde anvendelse ved udarbejdelsen af de opgørelser, som skal foretages i henhold til reglerne om CFC-beskatning. Spørgsmålet har givet anledning til overvejelser i såvel litteraturen som i...... anvendelse ved opgørelsen af et CFC-selskabs indkomst, medmindre det specifikt fremgår af den pågældende regel, dens lovforarbejder eller lignende, at reglen ikke er tiltænkt at skulle finde anvendelse i relation til CFC-selskaber....

  8. Klimavenlig majs ved minimal tilførsel af kvælstof

    OpenAIRE

    Ambus, Per

    2009-01-01

    Majs-biomasse kan omdannes til klimavenlig CO2-neutral energi ved behandling til bioetanol og biogas. Men gødskes majsen med affaldet fra biogasanlægget, dannes der betragtelige mængder af den kraftige drivhusgas, lattergas. Herved reduceres klimagevinsten mærkbart. Dyrkning af majs til energiformål skal derfor ske med ingen eller lille tilførsel af N.

  9. Vitaminer og fedtsyrer i hø og ensilage - hvad sker der ved forvejring og lagring?

    DEFF Research Database (Denmark)

    Jensen, Søren Krogh; Hymøller, Lone; Søegaard, Karen

    2010-01-01

    For at undersøge stabiliteten af vitaminer i moderne ensilage- og høproduktion, har FØJO III projektet ECOVIT, igennem to vækstår, målt vitaminindholdet i forskellige græsmarksafgrøder ved forskellige høsttidspunkter og sletintervaller. Resultaterne viser, at det største tab af vitaminer og...

  10. Det tidlige sprog hos børn med autisme - en afgørende udviklingsfaktor

    DEFF Research Database (Denmark)

    Brynskov, Cecilia; Eigsti, Inge-Marie

    2010-01-01

    bidrage til teorier om normaludviklingen. Denne artikel fokuserer på en afgørende faktor for prognosen ved autisme: den tidlige sprogudvikling. De tidlige sprogfærdigheder er en afgørende prædiktor for senere fungeren, såvel på kort som på langt sigt. Højtfungerende autisme (HFA) og Aspergers syndrom (AS...

  11. Implementering af organisatoriske forandringsprocesser ved indførelse af elektronisk aflevering og eksamen

    Directory of Open Access Journals (Sweden)

    Annette Q Pedersen

    2011-12-01

    Full Text Available

    Denne artikel opstiller ti gode råd om det organistoriske arbejde med forandringsprocesser ved indførelse af e-aflevering ud fra erfaringer fra Det Humanistiske Fakultet ved Københavns Universitet, hvor et stort projekt er i gang for at indføre elektronisk aflevering af de studerendes opgaver. De ti råd er 1: Start med det, der kan lade sig gøre, 2: Tro ikke det bare handler om teknik, 3: Men der skal være styr på både teknik og jura, 4: Giv plads til forandringstræthed, 5: Inddragelse og samarbejde giver bedre løsninger, 6: Skab succesoplevelser for så mange som muligt, 7: Kommunikation: Sørg for at alle ved, hvordan de skal gøre! 8: Kommunikation: Transparens i projektet, 9: Når der ikke er én rigtig og god løsning, må man opstille viften af alternativer, 10: Ledelsesopbakning. De gode råd er eksemplificeret med erfaringer fra det igangværende projekt.

  12. Implementering af organisatoriske forandringsprocesser ved indførelse af elektronisk aflevering og eksamen

    Directory of Open Access Journals (Sweden)

    Annette Q Pedersen

    2011-12-01

    Full Text Available Denne artikel opstiller ti gode råd om det organistoriske arbejde med forandringsprocesser ved indførelse af e-aflevering ud fra erfaringer fra Det Humanistiske Fakultet ved Københavns Universitet, hvor et stort projekt er i gang for at indføre elektronisk aflevering af de studerendes opgaver. De ti råd er 1: Start med det, der kan lade sig gøre, 2: Tro ikke det bare handler om teknik, 3: Men der skal være styr på både teknik og jura, 4: Giv plads til forandringstræthed, 5: Inddragelse og samarbejde giver bedre løsninger, 6: Skab succesoplevelser for så mange som muligt, 7: Kommunikation: Sørg for at alle ved, hvordan de skal gøre! 8: Kommunikation: Transparens i projektet, 9: Når der ikke er én rigtig og god løsning, må man opstille viften af alternativer, 10: Ledelsesopbakning. De gode råd er eksemplificeret med erfaringer fra det igangværende projekt.

  13. Vedāntic view of life: Reply to Gustavo Caetano-Anollés.

    Science.gov (United States)

    Shanta, Bhakti Niskama

    2016-01-01

    The author would like to thank Professor Gustavo Caetano-Anollés from Department of Crop Sciences, University of Illinois for his interest in his work. We may sometimes observe that there is a noticeable difference between the anecdote people narrate about the implications of a scientific paper and the real conclusion of the paper. Prof. Gustavo Caetano-Anollés's response(1) is an ideal example of the same, where he has tried to make great hay about the implications of the article "Life and consciousness - The Vedāntic view."(2) The Vedāntic view subscribes neither to the views of 'Creationist Movement'/'Intelligent Design', nor it supports some splendid anti-science proposal. Vedāntic view refutes the dominant reductionistic view of life in modern biology by proposing a viable alternative concept of 'Organic Whole' and thus serves a scientific critique to the nescience (avidyā) that is practiced on the name of science.

  14. Effekter og økonomiske konsekvenser ved afsaltet havvand til drikkevandsformål

    DEFF Research Database (Denmark)

    Rygaard, Martin

    2015-01-01

    væsentlige økonomiske gevinster ved at afsalte havvand til vandforsyningen i København. Besparelsen forudsætter, at det afsaltede vand remineraliseres med fluorid og magnesium, så risikoen for negative konsekvenser for sundhed reduceres. Besparelserne forventes at opnås allerede ved at erstatte >30% af...... Københavns nuværende vandforsyning med afsaltet havvand (se figur). Ved fuldstændigt at overgå til afsaltet havvand er den samlede besparelse anslået til €0,3 per m3 leveret drikkevand. Konklusion og perspektivering Studiet viser, at indførelse af afsaltet vand remineraliseret med magnesium og fluorid kan...... medføre økonomiske fordele for samfundet, der er større end de ekstra produktionsudgifter. Omvendt viser resultaterne også, at afsaltet vand med reduceret indhold af magnesium og fluorid kan have en negativ påvirkning af samfundsøkonomien. Baseret på studiet er der foreslået nye retningslinier for en...

  15. Functional characterization of Candida albicans Hos2 histone deacetylase [v3; ref status: indexed, http://f1000r.es/3xh

    Directory of Open Access Journals (Sweden)

    G Karthikeyan

    2014-07-01

    Full Text Available Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals. Azoles have been very effective anti-fungal agents and the mainstay in treating opportunistic mold and yeast infections. Azole resistant strains have emerged compromising the utility of this class of drugs. It has been shown that azole resistance can be reversed by the co-administration of a histone deacetylase (HDAC inhibitor, suggesting that resistance is mediated by epigenetic mechanisms possibly involving Hos2, a fungal deacetylase. We report here the cloning and functional characterization of HOS2 (HighOsmolarity Sensitive, a gene coding for fungal histone deacetylase from C. albicans. Inhibition studies showed that Hos2 is susceptible to pan inhibitors such as trichostatin A (TSA and suberoylanilide hydroxamic acid (SAHA, but is not inhibited by class I inhibitors such as MS-275. This in vitro enzymatic assay, which is amenable to high throughput could be used for screening potent fungal Hos2 inhibitors that could be a potential anti-fungal adjuvant. Purified Hos2 protein consistently deacetylated tubulins, rather than histones from TSA-treated cells. Hos2 has been reported to be a putative NAD+ dependent histone deacetylase, a feature of sirtuins. We assayed for sirtuin activation with resveratrol and purified Hos2 protein and did not find any sirtuin activity.

  16. HosA, a MarR Family Transcriptional Regulator, Represses Nonoxidative Hydroxyarylic Acid Decarboxylase Operon and Is Modulated by 4-Hydroxybenzoic Acid.

    Science.gov (United States)

    Roy, Ajit; Ranjan, Akash

    2016-02-23

    Members of the Multiple antibiotic resistance Regulator (MarR) family of DNA binding proteins regulate transcription of a wide array of genes required for virulence and pathogenicity of bacteria. The present study reports the molecular characterization of HosA (Homologue of SlyA), a MarR protein, with respect to its target gene, DNA recognition motif, and nature of its ligand. Through a comparative genomics approach, we demonstrate that hosA is in synteny with nonoxidative hydroxyarylic acid decarboxylase (HAD) operon and is present exclusively within the mutS-rpoS polymorphic region in nine different genera of Enterobacteriaceae family. Using molecular biology and biochemical approach, we demonstrate that HosA binds to a palindromic sequence downstream to the transcription start site of divergently transcribed nonoxidative HAD operon and represses its expression. Furthermore, in silico analysis showed that the recognition motif for HosA is highly conserved in the upstream region of divergently transcribed operon in different genera of Enterobacteriaceae family. A systematic chemical search for the physiological ligand revealed that 4-hydroxybenzoic acid (4-HBA) interacts with HosA and derepresses HosA mediated repression of the nonoxidative HAD operon. Based on our study, we propose a model for molecular mechanism underlying the regulation of nonoxidative HAD operon by HosA in Enterobacteriaceae family.

  17. A Voice for the Voiceless - Journalistisk alsidighed hos Al Jazeera English

    OpenAIRE

    Brusvang, Anne Emilie Frandsen; Rasmussen, Astrid Louise; Jensen, Margit Lundø; Værnet, Rosa Maria; Engrose, Felix; Aagren, Lærke

    2013-01-01

    Projektet undersøger journalistisk alsidighed hos Al Jazeera English (AJE), samt hvordan denne påvirkes af, at nyhedskanalen vil være stemme for dem uden stemme. Indledningsvis gives indblik i AJE gennem blandt andre Philip Seib og Hugh Miles, ligesom der redegøres for nyhedsteori samt Maxwell E. McCombs’ teori om mediernes dagsordensættende funktion. Med metodisk basis i David Hesmondhalgh og Stig Hjarvard udføres en indholdsanalyse og tre diskursanalyser af programmerne NewsHour og Inside S...

  18. Redskaber til vurdering af behov hos mennesker med kræft

    DEFF Research Database (Denmark)

    Steenfeldt, Vibeke Østergaard; Sølver, Lisbeth; Thomsen, Thora Grothe

    2015-01-01

    Regioner og kommuner implementerer systematisk behovsvurdering, som anbefalet i Forløbsprogram for rehabilitering og palliation, der fulgte Kræftplan III. I praksis er det imidlertid ikke entydigt, hvordan disse vurderinger skal foregå og på hvilket værdigrundlag. Artiklen retter opmærksomhed mod...... sondringen mellem problem og behov og beskriver to typer spørgeskemaer, som i dag anbefales til at vurdere behov for rehabilitering og palliation hos mennesker med kræft og andre livstruende sygdomme. I lyset af det fokus, der er på evidensbaseret praksis, reflekterer forfatterne over udviklingen på området...

  19. Förekomst av karies och parodontit hos personer med Morbus Crohn

    OpenAIRE

    Johansson, Annika; Olsson, Sara

    2012-01-01

    Syftet med litteraturstudien var att undersöka förekomsten av karies och parodontit hos personer med Morbus Crohn. Metoden som användes var en allmän litteraturstudie. Materialet till litteraturstudien samlades in genom sökning i databaserna Cinahl, PubMed och ScienceDirect. De sökord som användes vid litteratursökningen i samtliga databaser var ”caries”, ”Crohn’s disease”, ”periodontal disease” och ”periodontitis”. Vetenskapliga artiklar som fick ingå i litteraturstudien begränsades till ”En...

  20. Red Light-Mediated Degradation of CONSTANS by the E3 Ubiquitin Ligase HOS1 Regulates Photoperiodic Flowering in Arabidopsis.

    Science.gov (United States)

    Lazaro, Ana; Mouriz, Alfonso; Piñeiro, Manuel; Jarillo, José A

    2015-09-01

    The regulation of CONSTANS (CO) gene expression is crucial to accurately measure changes in daylength, which influences flowering time in Arabidopsis thaliana. CO expression is under both transcriptional and posttranslational control mechanisms. We previously showed that the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1) physically interacts with CO in Arabidopsis. This interaction is required to precisely modulate the timing of CO accumulation and, consequently, to maintain low levels of FLOWERING LOCUS T expression during the first part of the day. The data presented here demonstrate that HOS1 is involved in the red light-mediated degradation of CO that takes place in the early stages of the daylight period. Our results show that phytochrome B (phyB) is able to regulate flowering time, acting in the phloem companion cells, as previously described for CO and HOS1. Moreover, we reveal that phyB physically interacts with HOS1 and CO, indicating that the three proteins may be present in a complex in planta that is required to coordinate a correct photoperiodic response in Arabidopsis. © 2015 American Society of Plant Biologists. All rights reserved.

  1. 76 FR 16852 - Hours of Service (HOS) of Drivers; Assessing the Safety Impact of the Exemption From the 14-Hour...

    Science.gov (United States)

    2011-03-25

    ... Pyrotechnics Association (APA) an exemption from the current HOS prohibition against driving a commercial motor...: Thomas Yager, FMCSA Driver and Carrier Operations Division; Office of Bus and Truck Standards and... 381.300(b)). APA's Independence Day Operations and the Exemption from 49 CFR 395.3(a)(2) APA is a...

  2. Daphnoretin Induces Cell Cycle Arrest and Apoptosis in Human Osteosarcoma (HOS Cells

    Directory of Open Access Journals (Sweden)

    Jinhai He

    2012-01-01

    Full Text Available In this study antiproliferation, cell cycle arrest and apoptosis induced by daphnoretin in human osteosarcoma (HOS cells were investigated. Antiproliferative activity was measured with the 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay. The IC50 value of daphnoretin was 3.89 μM after 72 h treatment. Induction of apoptosis was evidenced by apoptotic body appearance and Annexin V-FITC/PI apoptosis detection kit. Flow cytometric analysis indicated daphnoretin arrested the cell cycle in the G2/M phase. Western-blot assay showed that the G2/M phase arrest was accompanied by down-regulation of cdc2, cyclin A and cyclin B1. Moreover, daphnoretin inhibited Bcl-2 expression and induced Bax expression to desintegrate the outer mitochondrial membrane and causing cytochrome c release. Mitochondrial cytochrome c release was associated with the activation of caspase-9 and caspase-3 cascade. Our results demonstrated that daphnoretin caused death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.

  3. Consciousness, cognition and the cognitive apparatus in the vedānta tradition.

    Science.gov (United States)

    Balasubramanian, R

    2011-01-01

    A human being is a complex entity consisting of the Self (also known as Consciousness), mind, senses and the body. The Vedānta tradition holds that the mind, the senses and the body are essentially different from the Self or Consciousness. It is through consciousness that we are able to know the things of the world, making use of the medium of the mind and the senses. Furthermore, the mind, though material, is able to reveal things, borrowing the light from consciousness. From the phenomenological point of view, we have to answer the following questions: how does one know the mind/the mental operations/the cogitations of the mind? Does the mind know itself? Is it possible? There is, again, the problem of the intentionality of consciousness. Is consciousness intentional? According to Vedānta, consciousness by its very nature is not intentional, but it becomes intentional through the mind. The mind or the ego is not part of the consciousness; on the contrary, it is transcendent to consciousness. It is difficult to spell out the relation between consciousness and the mind. How does consciousness, which is totally different from the mind, get related to the mind in such a way that it makes the latter capable of comprehending the things of the world? The Vedānta tradition provides the answer to this question in terms of the knower-known relation. Consciousness is pure light, self-luminous by its very nature, that is, although it reveals other objects, it is not revealed by anything else. When Sartre describes it as nothingness, bereft of even ego, it is to show that it is pure light revealing objects outside it.

  4. Akut psykose ved ophør af langvarig tramadolbehandling − overser vi tramadols serotonerge virkning?

    DEFF Research Database (Denmark)

    Østergaard Rathe, Jette; Dideriksen, Dorthe; Carstens, Jan

    2016-01-01

    I denne artikel præsenteres en sygehistorie, hvor en ældre kvinde får tiltagende konfusion og psykotiske symptomer en uge efter seponering af højdosis-tramadol og skift til Contalgin. Disse mulige seponeringssymptomer kan skyldes abrupt ophør af tramadols serotonerge effekt, og forfatterne...... konkluderer, at man må have skærpet opmærksomhed på atypiske bivirkninger i forbindelse med seponering af især langvarig/høj-dosering af tramadol, særligt hvis symptomerne ikke umiddelbart svinder ved morfinsubstitution....

  5. Kamerabasert navigasjon ved hjelp av landemerker med ukjent avstand fra kameraplanet

    OpenAIRE

    Engen, Simen Tvedt

    2015-01-01

    Kamerabasert navigasjon er en metode for å estimere posisjon og orientering til en plattform ved hjelp av informasjon fra optiske kamerabilder. Det kan være aktuelt i flere situasjoner. Eksempler på dette kan være der det ikke finnes eller er dårlig GPS dekning som innendørs, i et urbant miljø, under vann eller i situasjoner der hvor GPS signalet blir jammet . Oppgavens mål er å gjøre seg kjent med kamerabasert navigasjon og videre se om implementering av akselerasjon- og vinkelhastighetsmål...

  6. Metanpotentiale og metanudbytte af rørgræs ved forskellige slætstrategier

    DEFF Research Database (Denmark)

    Larsen, S U; Lærke, Poul Erik; Kandel, Tanka Prasad

    2013-01-01

    Rørgræs kan trives godt på våde arealer som f.eks. vandlidende tørvejorde, og biomassen kan potentielt bruges til biogasproduktion. På en tørvejord i Nørreådalen ved Viborg har Aarhus Universitet gennemført et forsøg med dyrkning af rørgræs, og det er undersøgt, hvordan slættidspunkt og antal slæ...

  7. Mere selvstudie med virtuelle læringsrum ved problembaseret læring

    DEFF Research Database (Denmark)

    Lorenzen, Henriette; Thomasen, Isa Neimann

    2017-01-01

    afslutningsvist formuleres en konklusion af en tredje studerende. Samtlige læringsmål bearbejdes efter samme princip, således at alle studerende på skift har ansvar for oplæg, respons og konklusion. Evaluation of the activity/course design, from student/teacher perspective: En kvantitativ evaluering viser, at 60......Students’ learning outcome of teaching activity/course presented: Ved Bioanalytikeruddannelsen i København anvender vi Problem Baseret Læring (PBL) med den såkaldte 7-trins PBL-model (Schmidt, 1983). De studerende føres gruppevis igennem en struktureret proces initieret af en åben...

  8. Expression, Functional Characterization and X-ray Analysis of HosA, A Member of MarR Family of Transcription Regulator from Uropathogenic Escherichia coli.

    Science.gov (United States)

    Roy, Ajit; Reddi, Ravikumar; Sawhney, Bhavik; Ghosh, Debasish Kumar; Addlagatta, Anthony; Ranjan, Akash

    2016-08-01

    Regulators belonging to multiple antibiotic resistance regulator (MarR) family are widespread in prokaryotes and are involved in regulation of genes that are responsible for virulence and pathogenicity in most of the clinically important pathogens. Here we report the transcriptional, biophysical, and X-ray analyses of homologue of SlyA (HosA), a member of MarR family that is predominantly present in the pathogenic strains of Enterobacteriaceae family. The initiation of hosA transcription was observed to occur at two independent start sites and subsequent binding study has revealed that the purified HosA interacts with its upstream region suggesting a probable autoregulation. The secondary structure analysis through circular dichroism spectroscopy demonstrated that HosA is predominantly composed of the alpha helix with higher thermal stability. To further understand the three-dimensional structure, HosA was crystallized and the crystals were diffracted to maximum of 2.9 Ǻ on exposure to X-rays. Analysis of the X-ray crystallographic data suggested a primitive space group (P 6 ? 2 2), with unit cell parameters a = b = 64.19 Å and c = 244.25 Å. The solvent content and Matthews coefficient were 41 % and 2.11 Å(3) Da(-1), respectively, which indicated the existence of two molecules of HosA in the asymmetric unit of crystal.

  9. Omkostningseffektivitet ved robot-assisteret laparoskopisk radikal prostatektomi versus åben radikal prostatektomi

    DEFF Research Database (Denmark)

    Hohwü, Lena; Ehlers, Lars Holger; Borre, Michael

    OMKOSTNINGSEFFEKTIVITET VED ROBOT-ASSISTERET LAPAROSKOPISK RADIKAL PROSTATEKTOMI VERSUS ÅBEN RADIKAL PROSTATEKTOMI Lena Hohwü1, Lars Ehlers2, Michael Borre1 og Knud Venborg Pedersen1 1 Århus Universitetshospital, Skejby 2 Institut for Erhvervsstudier, Aalborg Universitet   Introduktion: De...... økonomiske ressourcer mellem robot-assisteret laparoskopisk radikal prostatektomi (RALP) og åben radikal prostatektomi (RRP) diskuteres, da operationsomkostningerne for RALP forventes at være væsentlig højere. De økonomiske konsekvenser ved at indføre RALP er sparsomt beskrevet og baseret på heterogene...... år og D'Amico risiko-inddeling; 77 RALP, 154 RRP. Under antagelsen, at der opereres 70 RALP, fordelt på 110 robot-operationer, årligt, laves marginal-analyse på direkte omkostninger 1.postoperative år til estimering af inkremental cost-effectiveness ratio (ICER) per ekstra vellykket operation og per...

  10. Schmallenberg virus – et nyt virus hos drøvtyggere

    DEFF Research Database (Denmark)

    Lohse, Louise

    undersøgelser på laboratoriet, blev alle prøver i en længere periode testet negative for kendte patogener, der evt. kunne tænkes at knytte sig til disse sygdomsudbrud. Efterfølgende fandt man ved sekvensanalyse på DNA/RNA oprenset fra prøvematerialet lighed med virus fra orthobunyavirusgruppen. Disse virus er...... normalt vektorbårne og er kendt som årsag til sygdom i drøvtyggere i Australien, Asien, Afrika og Mellemøsten. Det nye virus blev kaldt Schmallenberg virus (SBV) efter stedet hvor det første tilfælde blev påvist. Siden har Schmallenberg virus spredt sig og er nu påvist i får, kvæg og geder i Tyskland......, Holland, Belgien, Luxembourg, Frankrig, Spanien, Italien og Storbritannien (status april 2012). Det antages, at virus overføres med mitter og myg og inkubationstiden har fra eksperimentelle forsøg vist sig at være kort (1-4 dage). Virus cirkulerer få dage i blodet og manifesterer sig ved milde uspecifikke...

  11. Kønsudvikling hos sønner af gartneriansatte kvinder

    DEFF Research Database (Denmark)

    Andersen, Helle Raun; Schmidt, Ida Maria; Grandjean, Philippe

    2008-01-01

      Flere pesticider er vist at være hor­mon­for­styr­rende i celle- eller dyreforsøg og epi­de­mio­lo­gi­ske undersøgelser tyder på, at tidlig eks­po­ne­ring for pesticider kan påvirke ud­vik­lingen af for­plantnings- og hor­mon­syste­met hos men­ne­sker. Formålet med denne prospektive under­søg­e...... un­der­søgelsen er tid­ligere publiceret i Environ­mental Health Perspective 2008;116:566-72. Udgivelsesdato: December...

  12. Development and Validation of Written Exam Items for the Agricultural Hazardous Occupations Orders (AgHOs) Certification Training Program.

    Science.gov (United States)

    Mann, A J; Field, W E; Tormoehlen, R; French, B F

    2016-04-01

    Research was conducted to develop and validate a pool of exam items that can be used to test the readiness of youth, ages 14-15 years, to be certified under the current federally mandated Agricultural Hazardous Occupations Orders (AgHOs). The AgHOs require training prior to employment in agricultural workplaces that the Secretary of Labor has determined are especially hazardous for youth within the prescribed age range. Under the current provisions of the AgHOs certification process, non-exempt youth seeking employment in agriculture are required to pass a written exam concentrating on safe work practices as partial satisfaction to receive certification of eligibility for employment to perform certain tasks. However, the regulations provide little guidance concerning the format of the exam, subject matter to be covered, degree of difficulty, or minimum passing score. As part of the USDA-sponsored Hazardous Occupations Safety Training in Agriculture (HOSTA) initiative, efforts have been made to develop consistent and evidence-based testing methods for disseminating the test protocols to instructors. The goal was to expand, enhance, and maintain the reliability of the exam item pool for the AgHOs certification process. Item development was based on the HOSTA-supported Gearing Up for Safety: Production Agriculture Safety Training for Youth curriculum. To ensure adequate item availability, the current item pool was expanded to include a minimum of two test items for each of the 157 cognitive-based core competencies developed as part of the Gearing Up curriculum design process. Administering 70-item exams that were generated from the item pool to 568 youth, ages 13-18 years, provided evidence of item validity. The result was a pool of 367 validated exam items.

  13. Stabile isotoper indikerer intra- og interspecifik variation i diæten hos tropiske ålelarver

    DEFF Research Database (Denmark)

    Grønkjær, P.; Christensen, Jens Tang; Munk, Peter

    2011-01-01

    Fødeøkologien hos ålens karakteristiske larvestadium, leptocephalen, er trods mange års studier stadig dårligt beskrevet. Én af grundene til dette er at der sjældent observeres identificerbare fødeobjekter i tarmen på disse larver. Nye molekylære teknikker har vist at dette muligvis skyldes, at g...

  14. On the Detectability of the X 2A" HSS, HSO, and HOS Radicals in the Interstellar Medium

    Science.gov (United States)

    Fortenberry, Ryan C.; Francisco, Joseph S.

    2017-02-01

    {\\tilde{X}}2A\\prime\\prime HSS has yet to be observed in the gas phase in the interstellar medium (ISM). HSS has been observed in cometary material and in high abundance. However, its agglomeration to such bodies or dispersal from them has not been observed. Similarly, HSO and HOS have not been observed in the ISM, either, even though models support their formation from reactions of known sulfur monoxide and hydrogen molecules, among other pathways. Consequently, this work provides high-level, quantum chemical rovibrational spectroscopic constants and vibrational frequencies in order to assist in interstellar searches for these radical molecules. Furthermore, the HSO-HOS isomerization energy is determined to be 3.63 kcal mol-1, in line with previous work, and the dipole moment of HOS is 36% larger at 3.87 D than HSO, making the less stable isomer more rotationally intense. Finally, the S-S bond strength in HSS is shown to be relatively weak at 30% of the typical disulfide bond energy. Consequently, HSS may degrade into SH and sulfur atoms, making any ISM abundance of HSS likely fairly low, as recent interstellar surveys have observed.

  15. Samtidig iltbehandling ved anstrengelsesudløst hypoksæmi forbedrer den fysiske formåen og reducerer åndenød hos patienter med KOL

    DEFF Research Database (Denmark)

    Kjeldgaard, Peter; Ringbæk, Thomas; Lange, Peter

    2011-01-01

    rehabilitation. These studies show that oxygen therapy during exercise results in significant improvement in exercise capacity. Yet it is not possible to draw a clear conclusion regarding the effects of more prolonged (weeks) treatment. The studies are in general small and of poor methodological quality....

  16. Å forstå smerten pasienten føler. Holdninger og smertelindring: hvilke utfordringer møter man ved opioidbruk i smertebehandlingen hos pasienter med langvarig smerte?

    OpenAIRE

    Langveg, Caroline V.; Rønning, Karoline S.

    2014-01-01

    NORSK: Bakgrunn: Pasienter med langvarig smerte får ofte utilstrekkelig smertelindring grunnet sin opioidbruk. Langvarig bruk av opioider fører til fysisk avhengighet, og sykepleiere frykter problematisk opioidbruk. Hensikt: Hensikten med denne litteraturstudien er å identifisere sykepleiernes utfordringer for å oppnå tilstrekkelig smertelindring med opioider til pasienter med langvarig smerte. Metode: Litteratursøkene til dette litteraturstudiet ble utført i databasene Academic Search Elite ...

  17. Numerisk modellering af formfyldning ved støbning i selvkompakterende beton

    DEFF Research Database (Denmark)

    Spangenberg, Jon

    dækker over mange emner. I denne afhandling er der fokuseret på tre af dem ved hjælp af Finite Difference Method (FDM) / Finite Volume Method (FVM) baserede Computational Fluid Dynamics (CFD) modeller udviklet i både FLOW-3D og MATLAB. Den første undersøgelse fokuserer på de komplikationer der er knyttet...... til at forudse separation under fyldning i SKB støbninger. De to FDM/FVM baserede CFD modeller afviger fra hinanden via deres tilslags repræsentation, som var en diskret metode (envejs momentum kobling) for den første og en skalar metode for den anden. Det viste sig, at det var mindst omfattende...

  18. Indledende undersøgelser af Wave Star lokaliteten ved Horns Rev

    DEFF Research Database (Denmark)

    Kramer, Morten

    Havområdet ved Horns Rev havvindmøllepark er, pga. tilslutningsmulighederne for el, egnet til udbygning med et eller flere demonstrationsanlæg baseret på bølgekraft. Nærværende rapport beskriver detaljerede undersøgelser vedr. placering af den næste skala 1:2 maskine af Wave Star på lokaliteten....... Formålet med nærværende skrift er at beskrive bølgerne på lokaliteten mht. bølgehøjde, -periode og -retning, at estimere årsproduktionen fra en skala 1:2 Wave Star maskine og forventet orientering af maskinen for maksimal årsproduktion samt at vurdere de største bølger i samspil med vandstand som kan...

  19. Detection of Disturbances in Voltage Signals for Power Quality Analysis Using HOS

    Directory of Open Access Journals (Sweden)

    José Luiz R. Pereira

    2007-01-01

    Full Text Available This paper outlines a higher-order statistics (HOS-based technique for detecting abnormal conditions in voltage signals. The main advantage introduced by the proposed technique refers to its capability to detect voltage disturbances and their start and end points in a frame whose length corresponds to, at least, N=16 samples or 1/16 of the fundamental component if a sampling rate equal to fs=256×60 Hz is considered. This feature allows the detection of disturbances in submultiples or multiples of one-cycle fundamental component if an appropriate sampling rate is considered. From the computational results, one can note that almost all abnormal and normal conditions are correctly detected if N= s256, 128, 64, 32, and 16 and the SNR is higher than 25 dB. In addition, the proposed technique is compared to a root mean square (rms-based technique, which was recently developed to detect the presence of some voltage events as well as their sources in a frame whose length ranges from 1/8 up to one-cycle fundamental component. The numerical results reveal that the proposed technique shows an improved performance when applied not only to synthetic data, but also to real one.

  20. Detection of Disturbances in Voltage Signals for Power Quality Analysis Using HOS

    Directory of Open Access Journals (Sweden)

    Pereira José Luiz R

    2007-01-01

    Full Text Available This paper outlines a higher-order statistics (HOS-based technique for detecting abnormal conditions in voltage signals. The main advantage introduced by the proposed technique refers to its capability to detect voltage disturbances and their start and end points in a frame whose length corresponds to, at least, samples or of the fundamental component if a sampling rate equal to Hz is considered. This feature allows the detection of disturbances in submultiples or multiples of one-cycle fundamental component if an appropriate sampling rate is considered. From the computational results, one can note that almost all abnormal and normal conditions are correctly detected if s256, 128, 64, 32, and 16 and the SNR is higher than 25 dB. In addition, the proposed technique is compared to a root mean square (rms-based technique, which was recently developed to detect the presence of some voltage events as well as their sources in a frame whose length ranges from up to one-cycle fundamental component. The numerical results reveal that the proposed technique shows an improved performance when applied not only to synthetic data, but also to real one.

  1. Den norske matvaretabellen og beregningsdatabasen ved Institutt for ernæringsforskning

    Directory of Open Access Journals (Sweden)

    Arnhild Haga Rimestad

    2009-11-01

    Full Text Available  SAMMENDRAGOpplysninger om matvarers innhold av energi og næringsstoffer er nødvendig i mange sammenhenger –for overvåking av kostholdet i ulike befolkningsgrupper, for studier av sammenhenger mellom kosthold,livsstil og helse, ved veiledning, undervisning og opplysning om et helsemessig godt kosthold. De flestevestlige land har en trykt matvaretabell som viser næringsinnholdet per 100 g matvare for etrepresentativt utvalg av de vanligste matvarene. Ved næringsberegning av kostholdsundersøkelser brukessom regel spesialtilpassete beregningsdatabaser, disse har ofte ikke-publiserte data i tillegg. Kvaliteten påden beregningsdatabasen som benyttes ved bearbeiding av kostholdsundersøkelser kan ha avgjørendebetydning for resultatene. Det er viktig at den databasen som benyttes blir omtalt i metodeavsnittet nårarbeidet publiseres. Matvaremarkedet endres stadig, fokus rettes mot nye næringsstoffer og analysemetodeneforbedres. Matvaretabellene og databasene må derfor revideres kontinuerlig. Næringsstoffinnholdet imatvarer varierer med sort, rase, fôring, dyrkingsbetingelser, lagring, transport, bearbeiding, oppskrifterog tilberedningsmetode. Siden mange av disse faktorene er forskjellig i forskjellige land, er det nødvendigå ha egne nasjonale matvaretabeller og databaser. For importerte matvarer kan det være forsvarlig å låneutenlandske verdier gitt at varen er av samme type, at håndteringen er lik og at næringsstoffdefinisjonerog analysemetoder er sammenlignbare. Det er viktig å fortsette det internasjonale samarbeidet med ågjøre tabellverk i ulike land sammenlignbare. Dette er en av forutsetningene for at resultatene frakostholdsundersøkelser i ulike land kan sammenlignes.Rimestad AH, Løken EB, Nordbotten A. The Norwegian food composition table and the database fornutrient calculations at the Institute for Nutrition Research. Nor J Epidemiol 2000; 10 (1: 7-16.ENGLISH SUMMARYFood composition data are needed for diet

  2. Sammenligning av to blodprøver fra samme person analysert ved to laboratorier

    Directory of Open Access Journals (Sweden)

    Aage Tverdal

    2009-10-01

    Full Text Available  INNLEDNINGEpidemiologiske undersøkelser av lipidnivået hosbefolkningen er helt avhengig av at analysemetodeneholder stabilt nivå over flere år. Dette er lettest å oppnåhvis man hele tiden benytter ett laboratorium, oghjerte-karundersøkelsene til Statens helseundersøkelserhar konsekvent benyttet Klinisk kjemisk avdeling,Ullevål sykehus. Ulike hensyn kan likevel tilsi at andrelaboratorier benyttes. Undersøkelsene til Universiteteti Tromsø som har har vært gjennomført fire ganger iperioden 1973-1995, har vært utført ved Kliniskkjemisk avdeling, Regionsykehuset i Tromsø. Helseundersøkelseni Nord-Trøndelag 1995-1997 harbenyttet Sentrallaboratoriet, Innherred sykehus. I dettearbeidet viser vi hvor store forskjellene blir hvisfeltlagene sender prøver fra samme person til ulikelaboratorier. Vi har undersøkt forskjellene mellomRegionsykehuset i Tromsø og Ullevål sykehus, ogmellom Innherred sykehus og Ullevål sykehus.

  3. Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

    DEFF Research Database (Denmark)

    Bergmann, Troels Korshøj; Mirza, Mansoor Raza; Andersen, Charlotte Brasch

    (fx ABCB1, CYP2C8, CYP3A4, SLCO1B3) korrelerer med farmakokinetik, toksicitet og effekt.  Design: Datasættet består af toksicitetsregistreringer, overlevelses-data og paclitaxelkoncentrationsbestemmelser i plasma (ende-punkter) og af SNP genotypning. Genotypen er uafhængigt og tilfældigt distribueret...... mellem patienterne og fungerer således som dobbeltblindede randomiserede expositioner. Data indsamles prospektivt ved at rekruttere patienter med æggestokkræft der skal have paclitaxel og carboplatin i Odense, Vejle, Herlev, Herning, Lund eller Linköping. Der tages blod fra til genanalyse og plasma til...... Common Toxicity Criteria der er internationalt anerkendt til formålet. SNP genotypning udføres på det formalin fikserede væv (både tumor og raskt væv) og på blod. Genotypen bestemmes med Multiplex-ligation dependent probe amplification (MLPA). Resultater: marts 2008: 71 patienter er inkluderet i den...

  4. Rice root curling, a response to mechanosensing, is modulated by the rice E3-ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE1 (OsHOS1).

    Science.gov (United States)

    Lourenço, T F; Serra, T S; Cordeiro, A M; Swanson, S J; Gilroy, S; Saibo, N J M; Oliveira, M M

    2016-08-02

    Plant development depends on the perception of external cues, such as light, gravity, touch, wind or nutrients, among others. Nevertheless, little is known regarding signal transduction pathways integrating these stimuli. Recently, we have reported the involvement of a rice E3-ubiquitin ligase (OsHOS1, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE1), previously associated with abiotic stress response, in root responses to mechanical stimuli. We showed that OsHOS1 is involved in the regulation of root curling after mechanosensing and that RNAi::OsHOS1 plants failed to exhibit the root curling phenotype observed in WT. Interestingly, the straight root phenotype of these transgenics correlated with the up-regulation of rice ROOT MEANDER CURLING (OsRMC, a negative regulator of rice root curling) and was reverted by the exogenous application of jasmonic acid. Altogether, our results highlight the role of the proteasome modulating plant responses to mechanical stimuli and suggest that OsHOS1 is a hub integrating environmental and hormonal signaling into plant growth and development.

  5. Undervisertip: Giv tid!

    DEFF Research Database (Denmark)

    Jakobsen, Uffe Lindberg Wewer

    2017-01-01

    Blogindlæg på LinkedIn om fordelene ved at øge refleksionstiden hos studerende i klasserumsundervisning.......Blogindlæg på LinkedIn om fordelene ved at øge refleksionstiden hos studerende i klasserumsundervisning....

  6. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 1 Leg 1, collected from 2010-08-13 to 2010-08-22, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0128072)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 01, to determine physical oceanographic parameters of the water...

  7. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 2 Leg 1, collected from 2010-08-26 to 2010-09-02, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0128093)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 02, to determine physical oceanographic parameters of the water...

  8. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 3 Leg 1, collected from 2010-09-09 to 2010-09-27, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0130017)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 03, to determine physical oceanographic parameters of the water...

  9. NRDA-processed CTD data from the HOS Davis in the Gulf of Mexico, Cruise 4 Leg 1, collected from 2010-11-07 to 2010-11-14, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0130023)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the R/V HOS Davis, Cruise 04, to determine physical oceanographic parameters of the water...

  10. Hvordan ser den ost ud, som De ikke ved, De vil elske om to år?

    DEFF Research Database (Denmark)

    Grunert, Klaus G.

    2006-01-01

    Kender de Deres "latente behov"? Det gør De selvfølgelig ikke. Det er jo definitionen af begrebet: Et latent behov er et behov, som man ikke ved, at man har, men som kommer til overfladen, når man møder det rigtige produkt, som opfylder netop dette behov. Latente behov vedrører derfor den ost, vi...... vil komme til at elske om to år, den funktionelle kantinemand, som vi ikke kan forestille os, eller den nutrigenomics-baserede specialkost, som vil tillade os at forene nydelse, helse og slankhed. Udgivelsesdato: 1. juni...

  11. Generelle aspekter ved mediereception? – Et bud på en multidimensional model for analyse af kvalitative receptionsinterviews

    Directory of Open Access Journals (Sweden)

    Kim Schrøder

    2003-09-01

    Full Text Available Findes der generelle aspekter ved receptionen af medieprodukter, som det kan være analytisk frugtbart at orientere sig efter, og som man altid bør belyse, når man analyserer kvalitative receptionsdata – og måske også allerede når man skal planlægge det empiriske feltarbejde i et em- pirisk receptionsprojekt? Denne artikel bygger på, at dette spørgsmål kan besvares bekræftende, og fremlægger et bud på, hvordan en multi- dimensional model for kvalitativ receptionsanalyse kunne se ud.

  12. Hvilke faktorer i studiemiljøet fremmer trivsel? - en analyse på baggrund af svar fra 11401 studerende ved Aarhus Universitet

    DEFF Research Database (Denmark)

    Herrmann, Kim Jesper; Jensen, Torben K.; Lassesen, Berit

    2012-01-01

    Alle danske universiteter gennemfører undervisningsmiljøvurderinger (UMV). Denne artikel præsenterer en analysemodel for UMV'en ved Aarhus Universitet samt en statistisk analyse med henblik på at identificere de vigtigste faktorer for studerendes trivsel.......Alle danske universiteter gennemfører undervisningsmiljøvurderinger (UMV). Denne artikel præsenterer en analysemodel for UMV'en ved Aarhus Universitet samt en statistisk analyse med henblik på at identificere de vigtigste faktorer for studerendes trivsel....

  13. Nasaleringsvärde för Nasometer hos svensktalande 13- och 18-åringar

    OpenAIRE

    Birgersson, Magdalena; Norberg, Christel

    2013-01-01

    Bakgrund Nasometer är ett datorbaserat instrument som procentuellt mäter andel ljudenergi som vid tal kommer ut via näsan. Nasometern är det främst använda instrumentet vid instrumentell nasalitetsbedömning. I användningen av Nasometer behövs normalvärden från personer med typisk resonansutveckling. Normalvärden för svenska språket finns för flera åldersgrupper, men inte för tonåringar. Syfte Ta fram normalvärden för Nasometer hos svensktalande 13- respektive 18-åringar, studera värdenas spri...

  14. Elevers produktion af multimodale tekster. Hvad ved vi og hvad mangler vi?

    Directory of Open Access Journals (Sweden)

    Vibeke Christensen

    2016-09-01

    Full Text Available I Danmark er der med de nye Fælles Mål fra 2014 indført et krav om, at eleverne skal kunne lave større multimodale produktioner. Også i de øvrige skandinaviske lande indgår arbejde med multimodale tekster med forskellig betegnelse i læreplanen for modersmålsfaget. Det er således relevant at undersøge, hvad man ved om elevers produktion af multimodale tekster. Denne artikel bidrager med en gennemgang af nordisk forskning inden for området og med udblik til den øvrige vestlige verden. Teoretisk beskrives multimodalitet med udgangspunkt i New London Groups programartikel fra 1996 og den udvikling af multimodalitet, som gruppen omkring Kress og van Leeuwen har bidraget med. Resultaterne af forskningsgennemgangen præsenteres i fem temaer: terminologi, didaktik, undervisning, elevudbytte og vurdering. Diskussion pågår løbende inden for hvert tema, og der peges på didaktiske perspektiver.Nøgleord: multimodale tekster, tekstkompetence, elevpræstation, skrive-pædagogik, produktion, vurderingAbstractIn the new curriculum for the subject Danish from 2014, it is a requirement that students should be able to create major multimodal productions. Working with multimodal texts in the mother tongue subject is included in the curricula for all three Scandinavian countries. Therefore, it is relevant to consider what is already recognized as students’ production of multi-modal texts. This article offers a brief review based on the Nordic research together with a brief look towards the rest of the Western world’s research on multimodality. This paper’s theoretical foundation is based on the New London Group’s article from 1996, “Pedagogy of Multiliteracies: Designing Social Futures”, and the development of multimodality that re-searchers and scholars surrounding Kress and van Leeuwen have contributed with. The results of the research will be presented in the following five themes: terminology, education, teaching, pupil performance

  15. Computer-aided diagnosis of Myocardial Infarction using ultrasound images with DWT, GLCM and HOS methods: A comparative study.

    Science.gov (United States)

    Vidya, K Sudarshan; Ng, E Y K; Acharya, U Rajendra; Chou, Siaw Meng; Tan, Ru San; Ghista, Dhanjoo N

    2015-07-01

    Myocardial Infarction (MI) or acute MI (AMI) is one of the leading causes of death worldwide. Precise and timely identification of MI and extent of muscle damage helps in early treatment and reduction in the time taken for further tests. MI diagnosis using 2D echocardiography is prone to inter-/intra-observer variability in the assessment. Therefore, a computerised scheme based on image processing and artificial intelligent techniques can reduce the workload of clinicians and improve the diagnosis accuracy. A Computer-Aided Diagnosis (CAD) of infarcted and normal ultrasound images will be useful for clinicians. In this study, the performance of CAD approach using Discrete Wavelet Transform (DWT), second order statistics calculated from Gray-Level Co-Occurrence Matrix (GLCM) and Higher-Order Spectra (HOS) texture descriptors are compared. The proposed system is validated using 400 MI and 400 normal ultrasound images, obtained from 80 patients with MI and 80 normal subjects. The extracted features are ranked based on t-value and fed to the Support Vector Machine (SVM) classifier to obtain the best performance using minimum number of features. The features extracted from DWT coefficients obtained an accuracy of 99.5%, sensitivity of 99.75% and specificity of 99.25%; GLCM have achieved an accuracy of 85.75%, sensitivity of 90.25% and specificity of 81.25%; and HOS obtained an accuracy of 93.0%, sensitivity of 94.75% and specificity of 91.25%. Among the three techniques presented DWT yielded the highest classification accuracy. Thus, the proposed CAD approach may be used as a complementary tool to assist cardiologists in making a more accurate diagnosis for the presence of MI. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. The RNA-binding protein HOS5 and serine/arginine-rich proteins RS40 and RS41 participate in miRNA biogenesis in Arabidopsis

    KAUST Repository

    Chen, Tao

    2015-07-30

    MicroRNAs are a class of small regulatory RNAs that are generated from primary miRNA (pri-miRNA) transcripts with a stem-loop structure. Accuracy of the processing of pri-miRNA into mature miRNA in plants can be enhanced by SERRATE (SE) and HYPONASTIC LEAVES 1 (HYL1). HYL1 activity is regulated by the FIERY2 (FRY2)/RNA polymerase II C-terminal domain phosphatase-like 1 (CPL1). Here, we discover that HIGH OSMOTIC STRESS GENE EXPRESSION 5 (HOS5) and two serine/arginine-rich splicing factors RS40 and RS41, previously shown to be involved in pre-mRNA splicing, affect the biogenesis of a subset of miRNA. These proteins are required for correct miRNA strand selection and the maintenance of miRNA levels. FRY2 dephosphorylates HOS5 whose phosphorylation status affects its subnuclear localization. HOS5 and the RS proteins bind both intronless and intron-containing pri-miRNAs. Importantly, all of these splicing-related factors directly interact with both HYL1 and SE in nuclear splicing speckles. Our results indicate that these splicing factors are directly involved in the biogenesis of a group of miRNA.

  17. Tarmmikrobiota som følsom indikator for biologisk relevante restkoncentrationer af kemiske pesticider i fødevarer eksemplificeret ved glyphosat (Roundup®)

    DEFF Research Database (Denmark)

    Nielsen, Lene Nørby; Bohse Hendriksen, Niels; Bay Gosewinkel, Ulrich

    livstilssygdomme som fx metabolisk syndrom. Restkoncentrationer af pesticider i fødevarer kan påvirke mikrobiota da flere pesticider, heriblandt glyphosat, er kendetegnet ved også at besidde antimikrobielle egenskaber. I forbindelse med risikovurdering af pesticider og fastlæggelse af grænseværdier for indtag er...... mikrobielle påvirkninger med eventuelt negative langsigtede konsekvenser stort set ikke belyst. Formål: At undersøge påvirkningen og minimums effekt koncentrationen (MEC) af pesticidet glyphosat, samt de hjælpestoffer (adjuvanter), der er til stede i det kommercielle produkt Roundup® på tarmmikrobiotaens...... sammensætning og funktion. Hypoteser: 1. Glyphosat påvirker forskellige bakteriegrupper i menneskets tarm forskelligt, og har dermed effekt på bakteriesamfundets (tarmmikrobiotaens) overordnede sammensætning og funktion. 2. Det kommercielle produkt Roundup® påvirker mikroorganismer ved lavere koncentrationer...

  18. "Toore puuga kütmine on raiskamine ..." = "Att elda med sur ved är slöseri ..." : [luuletused] / Gunnar D. Hansson ; tlk. Mati Sirkel

    Index Scriptorium Estoniae

    Hansson, Gunnar D.

    2004-01-01

    Sisu: "Toore puuga kütmine on raiskamine ..." = "Att elda med sur ved är slöseri ..."; "Esimest päeva rändab tuul ..." = "Första dagen vandrar vinden ..."; "Päike tuli lähemale ..." = "Solen kom närmare ..."; "Nagu oleks kõik möödas ..." = "Som om allt vore över ..."

  19. Computer-aided diagnosis of psoriasis skin images with HOS, texture and color features: A first comparative study of its kind.

    Science.gov (United States)

    Shrivastava, Vimal K; Londhe, Narendra D; Sonawane, Rajendra S; Suri, Jasjit S

    2016-04-01

    Psoriasis is an autoimmune skin disease with red and scaly plaques on skin and affecting about 125 million people worldwide. Currently, dermatologist use visual and haptic methods for diagnosis the disease severity. This does not help them in stratification and risk assessment of the lesion stage and grade. Further, current methods add complexity during monitoring and follow-up phase. The current diagnostic tools lead to subjectivity in decision making and are unreliable and laborious. This paper presents a first comparative performance study of its kind using principal component analysis (PCA) based CADx system for psoriasis risk stratification and image classification utilizing: (i) 11 higher order spectra (HOS) features, (ii) 60 texture features, and (iii) 86 color feature sets and their seven combinations. Aggregate 540 image samples (270 healthy and 270 diseased) from 30 psoriasis patients of Indian ethnic origin are used in our database. Machine learning using PCA is used for dominant feature selection which is then fed to support vector machine classifier (SVM) to obtain optimized performance. Three different protocols are implemented using three kinds of feature sets. Reliability index of the CADx is computed. Among all feature combinations, the CADx system shows optimal performance of 100% accuracy, 100% sensitivity and specificity, when all three sets of feature are combined. Further, our experimental result with increasing data size shows that all feature combinations yield high reliability index throughout the PCA-cutoffs except color feature set and combination of color and texture feature sets. HOS features are powerful in psoriasis disease classification and stratification. Even though, independently, all three set of features HOS, texture, and color perform competitively, but when combined, the machine learning system performs the best. The system is fully automated, reliable and accurate. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. Overexpression of an Orchid (Dendrobium nobile) SOC1/TM3-Like Ortholog, DnAGL19, in Arabidopsis Regulates HOS1-FT Expression.

    Science.gov (United States)

    Liu, Xiao-Ru; Pan, Ting; Liang, Wei-Qi; Gao, Lan; Wang, Xiao-Jing; Li, Hong-Qing; Liang, Shan

    2016-01-01

    Flowering in the appropriate season is critical for successful reproduction in angiosperms. The orchid species, Dendrobium nobile, requires vernalization to achieve flowering in the spring, but the underlying regulatory network has not been identified to date. The MADS-box transcription factor DnAGL19 was previously identified in a study of low-temperature treated D. nobile buds and was suggested to regulate vernalization-induced flowering. In this study, phylogenetic analysis of DnAGL9 and the MADS-box containing proteins showed that DnAGL19 is phylogenetically closely related to the SOC1-like protein from orchid Dendrobium Chao Parya Smile, DOSOC1. The orchid clade closed to but is not included into the SOC1-1/TM3 clades associated with either eudicots or monocots, suggesting that DnAGL19 is an SOC1-1/TM3-like ortholog. DnAGL19 was found to be highly expressed in pseudobulbs, leaves, roots, and axillary buds but rarely in flowers, and to be substantially upregulated in axillary buds by prolonged low-temperature treatments. Overexpression of DnAGL19 in Arabidopsis thaliana resulted in a small but significantly reduced time to bolting, suggesting that flowering time was slightly accelerated under normal growth conditions. Consistent with this, the A. thaliana APETELA1 (AP1) gene was expressed at an earlier stage in transgenic lines than in wild type plants, while the FLOWERING LOCUS T (FT) gene was suppressed, suggesting that altered regulations on these transcription factors caused the weak promotion of flowering. HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1) was slightly activated under the same conditions, suggesting that the HOS1-FT module may be involved in the DnAGL19-related network. Under vernalization conditions, FT expression was significantly upregulated, whereas HOS1 expression in the transgenic A. thaliana has a level similar to that in wild type. Taken together, these results suggest that DnAGL19 controls the action of the HOS1-FT module

  1. Overexpression of an orchid (Dendrobium nobile SOC1/TM3-like ortholog, DnAGL19, in Arabidopsis regulates HOS1-FT expression

    Directory of Open Access Journals (Sweden)

    Xiao-ru eLiu

    2016-02-01

    Full Text Available Flowering in the appropriate season is critical for successful reproduction in angiosperms. The orchid species, Dendrobium nobile, requires vernalization to achieve flowering in the spring, but the underlying regulatory network has not been identified to date. The MADS-box transcription factor DnAGL19 was previously identified in a study of low-temperature treated D. nobile buds and was suggested to regulate vernalization-induced flowering. In this study, phylogenetic analysis of DnAGL9 and the MADS-box containing proteins showed that DnAGL19 is phylogenetically closely related to the SOC1-like protein from orchid Dendrobium Chao Parya Smile, DOSOC1. The orchid clade closed to but is not included into the SOC1-1/TM3 clades associated with either eudicots or monocots, suggesting that DnAGL19 is an SOC1-1/TM3-like ortholog. DnAGL19 was found to be highly expressed in pseudobulbs, leaves, roots and axillary buds but rarely in flowers, and to be substantially upregulated in axillary buds by prolonged low-temperature treatments. Overexpression of DnAGL19 in Arabidopsis thaliana resulted in a small but significantly reduced time to bolting, suggesting that flowering time was slightly accelerated under normal growth conditions. Consistent with this, the A. thaliana APETELA1 (AP1 gene was expressed at an earlier stage in transgenic lines than in wild type plants, while the FLOWERING LOCUS T (FT gene was suppressed, suggesting that altered regulations on these transcription factors caused the weak promotion of flowering. HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1 was slightly activated under the same conditions, suggesting that the HOS1-FT module may be involved in the DnAGL19-related network. Under vernalization conditions, FT expression was significantly upregulated, whereas HOS1 expression in the transgenic A. thaliana has a level similar to that in wild type. Taken together, these results suggest that DnAGL19 controls the action of the

  2. Vad underlättar respektive hindrar fysisk aktivitet hos personer med långvariga smärtor? : En kvalitativ intervjustudie

    OpenAIRE

    Strömbom, Johanna; Carlsson, Malin

    2014-01-01

    Titel: Vad underlättar respektive hindrar fysisk aktivitet hos personer med långvariga smärtor? – En kvalitativ intervjustudie. Författare: Malin Carlsson & Johanna Strömbom, Sjukgymnastprogrammet, Institutionen för Medicin och Hälsa (IMH), Linköpings universitet Handledare: Britt Larsson, Docent i yrkesmedicin, Lektor i klinisk smärtforskning, Institutionen för Medicin och Hälsa (IMH), Linköpings universitet. SAMMANFATTNING Bakgrund: Träning har visats ge positiva effekter på långvarig s...

  3. Overexpression of an Orchid (Dendrobium nobile) SOC1/TM3-Like Ortholog, DnAGL19, in Arabidopsis Regulates HOS1-FT Expression

    Science.gov (United States)

    Liu, Xiao-Ru; Pan, Ting; Liang, Wei-Qi; Gao, Lan; Wang, Xiao-Jing; Li, Hong-Qing; Liang, Shan

    2016-01-01

    Flowering in the appropriate season is critical for successful reproduction in angiosperms. The orchid species, Dendrobium nobile, requires vernalization to achieve flowering in the spring, but the underlying regulatory network has not been identified to date. The MADS-box transcription factor DnAGL19 was previously identified in a study of low-temperature treated D. nobile buds and was suggested to regulate vernalization-induced flowering. In this study, phylogenetic analysis of DnAGL9 and the MADS-box containing proteins showed that DnAGL19 is phylogenetically closely related to the SOC1-like protein from orchid Dendrobium Chao Parya Smile, DOSOC1. The orchid clade closed to but is not included into the SOC1-1/TM3 clades associated with either eudicots or monocots, suggesting that DnAGL19 is an SOC1-1/TM3-like ortholog. DnAGL19 was found to be highly expressed in pseudobulbs, leaves, roots, and axillary buds but rarely in flowers, and to be substantially upregulated in axillary buds by prolonged low-temperature treatments. Overexpression of DnAGL19 in Arabidopsis thaliana resulted in a small but significantly reduced time to bolting, suggesting that flowering time was slightly accelerated under normal growth conditions. Consistent with this, the A. thaliana APETELA1 (AP1) gene was expressed at an earlier stage in transgenic lines than in wild type plants, while the FLOWERING LOCUS T (FT) gene was suppressed, suggesting that altered regulations on these transcription factors caused the weak promotion of flowering. HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1) was slightly activated under the same conditions, suggesting that the HOS1-FT module may be involved in the DnAGL19-related network. Under vernalization conditions, FT expression was significantly upregulated, whereas HOS1 expression in the transgenic A. thaliana has a level similar to that in wild type. Taken together, these results suggest that DnAGL19 controls the action of the HOS1-FT module

  4. Design og implementering af to virkemidler, der skal forbedre kvaliteten og øge status af undervisning ved universitetet

    DEFF Research Database (Denmark)

    Dolin, Jens; Kobayashi, Sofie

    med at designe og implementere PKP og UVPF er på mange måder et ideelt eksempel på en kombineret top-down og bottom-up proces. Til sikring organisatorisk accept af disse og fremtidige virkemidler har vi derfor formuleret følgende Forskningsspørgsmål Hvilke barrierer hindrer og hvilke drivkræfter...... gennemførelsen af to af disse initiativer: En Pædagogisk Kompetence Profil (PKP), og en undervisningsportfolio (UVPF). Design og implementeringsproces En projektgruppe med dygtige undervisere og ressourcepersoner fra hvert af de seks fakulteter blev udpeget til at designe en PKP og få den bredt anerkendt på...... universitetet. En lignende projektgruppe blev udnævnt til at designe og implementere UVPF, med det mål at alle undervisere skal have en UVPF ved udgangen af 2016. PKP projektgruppen baserede sit arbejde på nogle centrale principper: Styrkelsen af de studerendes læring skal være i centrum for alle elementer i...

  5. Monitorering af fysisk aktivitetsniveau (MOAN) hos indlagte patienter på geriatrisk afdeling - forsøgsprotokol

    DEFF Research Database (Denmark)

    Villumsen, Morten; Jørgensen, Martin Grønbech; Andreasen, Jane

    (4):451-8. (2) Potter R, Ellard D, Rees K, Thorogood M. A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia. Int J Geriatr Psychiatry 2011 Oct;26(10):1000-11. (3) Årsrapport 2010 - DEN LANDSDÆKKENDE KVALITETSDATABASE......Baagrund: Effekten af fysisk aktivitet og ikke mindst inaktivitet er veldokumenteret og har banet vejen frem mod ideen om det fysisk aktive sygehus, som også Aalborg sygehus arbejder aktivt med. Når ældre og svage patienter taber funktionniveau under indlæggelse er der stor risiko for at de aldrig...... genvinder disse igen.(1) Der er desuden god dokumentation for at også ældre patienter med demens kan forbedre funktionsniveau ved træning.(2) Særligt styrketræning af underekstremiteterne med høj intensitet, har vist sig at være effektivt. Hvilket blandt andet har kunnet registreres med ”Timed up and go...

  6. Specialevejledning på seks måneder: De nye specialeregler belyst ved erfaringer fra Institut på Statskundskab, Københavns Universitet

    Directory of Open Access Journals (Sweden)

    Hanne Nexø Jensen

    2013-03-01

    Full Text Available Artiklen, der bl.a. bygger på resultaterne fra en spørgeskemaundersøgelse blandt specialevejledere på Institut for Statskundskab, KU, viser, at 6-månedersreglen har ført til mere fokus på tidsfaktoren i specialevejledningen, men formentlig også lidt ændrede krav til vejlederne.  Holdningen til 6-månedersreglen hos vejlederne er den samme som hos de studerende, nemlig positiv.In 2007, a 6-months deadline for thesis writing was introduced as a new rule at the Danish Universities. Based, among other things, on the findings from a survey among thesis supervisors at the Department of Political Science, University of Copenhagen, the article shows that the rule has had impacts on the supervision practice. It has led to more focus among supervisors on the time factor, but probably also slightly changed student demands for supervision. The supervisors’ attitude to the rule is the same as the students, namely positive.

  7. Specialevejledning på seks måneder: De nye specialeregler belyst ved erfaringer fra Institut på Statskundskab, Københavns Universitet

    Directory of Open Access Journals (Sweden)

    Hanne Nexø Jensen

    2013-03-01

    Full Text Available Artiklen, der bl.a. bygger på resultaterne fra en spørgeskemaundersøgelse blandt specialevejledere på Institut for Statskundskab, KU, viser, at 6-månedersreglen har ført til mere fokus på tidsfaktoren i specialevejledningen, men formentlig også lidt ændrede krav til vejlederne.  Holdningen til 6-månedersreglen hos vejlederne er den samme som hos de studerende, nemlig positiv. In 2007, a 6-months deadline for thesis writing was introduced as a new rule at the Danish Universities. Based, among other things, on the findings from a survey among thesis supervisors at the Department of Political Science, University of Copenhagen, the article shows that the rule has had impacts on the supervision practice. It has led to more focus among supervisors on the time factor, but probably also slightly changed student demands for supervision. The supervisors’ attitude to the rule is the same as the students, namely positive.

  8. Ti års erfaring med førstetrimester screening for føtal aneuploidi ved hjælp af biokemi fra gestationsuge 6+0 til 13+6

    DEFF Research Database (Denmark)

    Tørring, Niels; Petersen, Olav Bjørn; Uldbjerg, Niels

    2014-01-01

    i gestationsugerne 8-10. Formål At validere resultaterne af det danske screeningsprogram af første trimester screening for føtal trisomi 21, trisomi 13, trisomi 18 samt triploidi i perioden 2003 til 2013 Datasæt Region Midtjyllands database (RM) (oktober 2003 til oktober 2013); n = 147.......768. (blodprøver overvejende fra gestationsuge 8-10) Den Nationale FøtoDatabase (FD) (oktober 2008 til august 2011); n = 220.739 (blodprøver fra gestationsuge 8-13) Resultater Detektion af Trisomi 21: Første trimester ved cut off 1:300. Den signifikant bedre detektionsrate for føtal trisomi 21 ved brug af...... for føtal aneuploidi. Brug af blodprøve fra gestationsuge 9 viser signifikant højere detektionsrate for føtal trisomi 21 end ved brug af blodprøve senere...

  9. Endring i adaptiv atferd hos eldre personer med utviklingshemning - en sammenligning mellom personer med Down syndrom og personer med annen utviklingshemning

    Directory of Open Access Journals (Sweden)

    Anne Marit Bygdnes

    2012-01-01

    Materiale og metode: Undersøkelsen omfatter 87 personer med utviklingshemning som tidligere har bodd på en sentralinstitusjon. Datainnsamling skjedde ved at omsorgspersoner fylte ut ABDQ.  Resultater: Det var 24 % i utvalget som hadde nedgang i adaptiv atferd. Fortolkning: ABDQ er et hjelpemiddel til å avdekke nedgang i adaptiv atferd. Det er viktig at svikt avdekkes tidligst mulig og videreformidles til helsepersonell for utredning, diagnostisering, relevant behandling og tilrettelagte helse- og omsorgstjenester. Mange personer med utviklingshemning mestrer ikke å informere om egen helsetilstand og er avhengig av at omsorgspersonalet kan avdekke sykdom og lidelser så tidlig som mulig i sykdomsforløpet.

  10. Toleranse i religionsundervisning : en drøfting av ulike aspekter ved moderne og postmoderne toleranse i lys av lærebøker i Religion og etikk

    OpenAIRE

    Kristensen, Frode

    2012-01-01

    Med utgangspunkt i mitt forskningsarbeid om toleranse og dialog i lærebøkene, vil jeg drøfte om det finnes aspekter ved forståelsen av toleranse som passer til den postmoderne modellen. Det primære forskningsspørsmålet jeg vil besvare, er dermed om det finnes grunnlag for å si at det finnes postmoderne aspekter ved den toleranselæringen som skjer i religionsundervisningen på videregående skole gjennom lærebøkene. Hvordan kan vi eventuelt si at dette skjer? Eller hvordan kan vi si at dette ikk...

  11. Strategi for opptrapping av kraftfôr etter kjeing for å sikre god produksjon og helse hos norske mjølkegeiter

    OpenAIRE

    Asheim, Karianne Garthus

    2016-01-01

    I Norge har mjølkeavdråtten hos geit økt mye i seinere tid. Etter kjeing er geiter ofte i negativ energibalanse (NEB), og fôring av kraftfôr må balanseres mellom tilførsel av nok energi, og samtidig unngå for mye mobilisering av kroppsreserver og sikre godt vommiljø og grovfôropptak videre i laktasjonen. Formålet med denne oppgaven var å undersøke effekten av forskjellige opptrappingshastigheter for kraftfôr etter kjeing. Et feltforsøk ble utført i 8 besetninger med geitemjølksproduksjon ...

  12. Effekt av protein i rasjonen på fôropptak, melkeytelse, melkekvalitet, tyggeatferd, og aktivitet hos melkekyr med ulik fôreffektivitet

    OpenAIRE

    Skjelbred, Camilla Therese

    2017-01-01

    Formålet med dette forsøket var å undersøke effekten av ulik fôreffektivitet (høy og lav) hos kyr, og ulikt proteinnivå (130, 145, 160, 175 g/kg TS) i fullfôret på fôropptak, melkeytelse, melkekvalitet, tyggeatferd og aktivitet. Kyr og andre drøvtyggere lever i symbiose med mikrobene i vomma som brytes ned cellulose og hemi-cellulose i fôret. For at mikrobene skal fungere optimalt er det viktig at miljøet i vomma er stabilt. En viktig del av fôret til kyrne er protein, og dette tilsettes i...

  13. Cancerrisiko ved topikale immunmodulatorer

    DEFF Research Database (Denmark)

    Deleuran, Mette; Zachariae, Claus; Thestrup-Pedersen, Kristian

    2009-01-01

    This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non-melanom...

  14. Osteoporose ved Parkinsons sygdom

    DEFF Research Database (Denmark)

    Ezzatian-Ahar, Shabnam; Schwarz, Peter; Pedersen, Stephen Wørlich

    2015-01-01

    The risk of developing osteoporosis, as well as Parkinson's disease (PD) is increased with increasing age, resulting in increased risk of fracture, particularly hip fractures. Each one of these two conditions can be debilitating and affect the individual patient's quality of life negatively. PD...

  15. Mikrokirurgi ved plastikkirurgiske indgreb

    DEFF Research Database (Denmark)

    Bonde, Christian T; Jensen, Lisa Toft; Tos, Tina

    2016-01-01

    The most common indication for free flap surgery is breast reconstruction. Deep inferior epigastric perforator flaps are safe, quick and provide excellent cosmetic results. The reconstruction in head and neck cancer patients is more complex. The aims are preservation of function and appearance....... Free flaps are important in traumatology and the timing of intervention can make the difference between amputation and extremity conserving treatment. Due to the improvement in surgical technique failure rates as low as 2% can be seen. Post-operative monitoring is well-established in all microsurgical...

  16. Aprotininskintigrafi ved amyloidose

    DEFF Research Database (Denmark)

    Haraldsen, Ate; Eskild-Jensen, Anni; Frøkiær, Jørgen

    2009-01-01

    Amyloidosis is a disease characterized by protein deposition (amyloid) in THE extracellular matrix leading to organ dysfunction and death. New treatment modalities have emphasized the need for accurate and early diagnosis. Aprotinin scintigraphy is a radionuclide imaging technique in which...

  17. Cancerrisiko ved topikale immunmodulatorer

    DEFF Research Database (Denmark)

    Deleuran, Mette; Zachariae, Claus; Thestrup-Pedersen, Kristian

    2009-01-01

    This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non...

  18. Mikrokirurgi ved plastikkirurgiske indgreb

    DEFF Research Database (Denmark)

    Bonde, Christian T; Jensen, Lisa Toft; Tos, Tina

    2016-01-01

    . Free flaps are important in traumatology and the timing of intervention can make the difference between amputation and extremity conserving treatment. Due to the improvement in surgical technique failure rates as low as 2% can be seen. Post-operative monitoring is well-established in all microsurgical...

  19. Helbredsrelateret livskvalitet ved kraeft

    DEFF Research Database (Denmark)

    Grønvold, Mogens

    2008-01-01

    The article reviews methods, experiences, and results of quality of life research in cancer, and presents recommendations. The research has comprised descriptive studies, end-points in clinical trials, prognostic studies, and clinical applications of quality of life questionnaires. There is a nee...

  20. Mikrokirurgi ved plastikkirurgiske indgreb

    DEFF Research Database (Denmark)

    Bonde, Christian T; Jensen, Lisa Toft; Tos, Tina

    2016-01-01

    The most common indication for free flap surgery is breast reconstruction. Deep inferior epigastric perforator flaps are safe, quick and provide excellent cosmetic results. The reconstruction in head and neck cancer patients is more complex. The aims are preservation of function and appearance...

  1. Smerter ved akut myokardieinfarkt

    DEFF Research Database (Denmark)

    Nielsen, F E; Sørensen, H T; Klausen, I C

    1989-01-01

    Pain is the most constant symptom in acute myocardial infarction (AMI) but there are considerable variations. It is possible that pain may indirectly cause extension of the infarct. The authors have, therefore, undertaken a retrospective investigation of 87 unselected patients admitted consecutiv...

  2. Vejledning ved ambulancetransport

    DEFF Research Database (Denmark)

    Berlac, Peter Anthony; Wammen, Susanne; Giebner, Matthias

    2010-01-01

    Inter-hospital transportation poses potential risks to staff and patients. The present guidelines recommend competency-based management dictated by the patient's clinical condition and medical requirements during transfer. The guidelines aim to: 1) improve patient and staff safety during transport...

  3. Formidlingsprovision ved inversteringsbeviser

    DEFF Research Database (Denmark)

    Bechmann, Ken L.; Wendt, Peter

    2012-01-01

    Investeringsforeningernes betaling af formidlingsprovision er blevet kritiseret, men egentlig viden om denne årlige betaling til pengeinstitutterne har været meget begrænset. Dette er nok en af forklaringerne på, at Penge- og Pensionspanelet i 2011 iværksatte en undersøgelse af formidlingsprovisi...

  4. Cimetidinbehandling ved cancer ventriculi

    DEFF Research Database (Denmark)

    Tønnesen, H; Knigge, U P; Bülow, S

    1989-01-01

    The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo...

  5. Nitrogenoxidinhalation ved akut lungesvigt

    DEFF Research Database (Denmark)

    Jensen, T H; Henneberg, S W; Heslet, L

    1995-01-01

    . NO inhalation substantially improved oxygenation, reduced pulmonary arterial pressure and peak inspiratory pressure. Treatment with NO inhalation was without side effects and easy to administer through the ventilator. Both patients survived without sequelae. We suggest that inhalation with NO should be tried...

  6. Cancerrisiko ved topikale immunmodulatorer

    DEFF Research Database (Denmark)

    Deleuran, Mette; Zachariae, Claus; Thestrup-Pedersen, Kristian

    2009-01-01

    This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non-melanom......-melanoma skin cancer and lymphoma. So far, no studies support that the use of topical immunosuppression increases the risk of local or systemic cancer.......This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non...

  7. Cancerrisiko ved topikale immunmodulatorer

    DEFF Research Database (Denmark)

    Deleuran, Mette; Zachariae, Claus; Thestrup-Pedersen, Kristian

    2009-01-01

    This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non-melanom......-melanoma skin cancer and lymphoma. So far, no studies support that the use of topical immunosuppression increases the risk of local or systemic cancer. Udgivelsesdato: 2009-Aug-24......This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non...

  8. Medicinproblemer ved sektorskifte

    DEFF Research Database (Denmark)

    Christensen, Hanne Rolighed; Krølner, Bjørn K

    2009-01-01

    of responsibilities, lack of communication, frequent exchanges between synonymous and analogous drugs, polypharmacy, compliance issues and insufficient education and training of staff. There is an obvious need for a joint internet-based online prescription system covering all physicians. Udgivelsesdato: 2009-Mar...

  9. Det varer ved

    DEFF Research Database (Denmark)

    Pedersen, Jens Olaf Pepke

    2017-01-01

    Naturvidenskaben siger ikke, at livet ikke har mening, Den siger blot, at den ikke kan besvare spørgsmålet. Som forsker kan man– også uden at være troende – deducere sig frem til, at kristendommen udgør et filosofisk tilfredsstillende grundlag for tilværelsen.......Naturvidenskaben siger ikke, at livet ikke har mening, Den siger blot, at den ikke kan besvare spørgsmålet. Som forsker kan man– også uden at være troende – deducere sig frem til, at kristendommen udgør et filosofisk tilfredsstillende grundlag for tilværelsen....

  10. Medicineringsfejl ved generisk substitution

    DEFF Research Database (Denmark)

    Rölfing, Jan

    2012-01-01

    Generic substitution is a major cause of medical mistakes in the general population. Danish legislation obligates pharmacies to substitute prescribed medicine with the cheapest equivalent formulation, despite variations in product name, packaging, shape and colour. Consequently, medical mistakes...... occur. Scientific evidence on the consequences of generic substitution is sparse. Call upon fellow health workers to report medical mistakes to the national entities and scientific peers, in order to increase awareness and scientific evidence about the problem....

  11. Immunsystemet ved kronisk inflammation

    DEFF Research Database (Denmark)

    Bendtzen, Klaus

    2008-01-01

    Innate and adaptive immunity has evolved as a defence against infections and as an important repair mechanism after physical injury. If elimination of microbes and healing is not achieved, or if the immune system is dysregulated, chronic inflammation ensues. Immune cells become engaged in prolonged...

  12. Vejledning ved ambulancetransport

    DEFF Research Database (Denmark)

    Berlac, Peter Anthony; Wammen, Susanne; Giebner, Matthias

    2010-01-01

    Inter-hospital transportation poses potential risks to staff and patients. The present guidelines recommend competency-based management dictated by the patient's clinical condition and medical requirements during transfer. The guidelines aim to: 1) improve patient and staff safety during transpor...

  13. Dyskinesier ved Parkinsons sygdom:

    DEFF Research Database (Denmark)

    Thomsen, Birgitte Liang Chen; Herz, Damian Marc; Siebner, Hartwig Roman

    2017-01-01

    and may help to identify patients at risk of developing LID. Amantadine can be used for the treatment of LID, and novel drugs are under development. Deep brain stimulation of the subthalamic nucleus and globus pallidus internus alleviates LID, the former indirectly by reducing levodopa intake, the latter...

  14. Trombolysebehandling ved akut underekstremitetsiskaemi

    DEFF Research Database (Denmark)

    Rørdam, Peter; Enevoldsen, Micha Thyge; Rasmussen, John Bøje Grønvall

    1996-01-01

    died within one month and limb salvage was 69%. During 22 months (3-48) of follow-up another six patients were amputated two to nine months later. The 18 salvaged lower extremities (49%) had an ankle-brachial pressure index of 0.63 (0.30-1.-09). Review of all angiograms revealed a demonstrable effect...... of thrombolytic therapy only in 13 (35%) cases. In conclusion, thrombolytic therapy should be considered in the case of acute lower extremity ischaemia unsuitable for reconstructive procedures. Even though the effect of thrombolytic therapy cannot be demonstrated on the angiogram, that should not necessarily deem...

  15. Psykologiske aspekter ved overvaegt

    DEFF Research Database (Denmark)

    Madsen, Svend Aage; Grønbaek, Helle; Olsen, Hanne

    2006-01-01

    Although knowledge of the biological aspects of obesity is increasing very rapidly, psychological approaches are increasingly in demand. Psychological theory and research concerning the emotional and cognitive impacts of being obese, the psychological causes involved in obesity, and the psycholog......Although knowledge of the biological aspects of obesity is increasing very rapidly, psychological approaches are increasingly in demand. Psychological theory and research concerning the emotional and cognitive impacts of being obese, the psychological causes involved in obesity......, and the psychological elements of treatment and motivations for treatment are requested. There is no clear separation between the psychological factors that function as causes of obesity and the psychological effects of obesity. Rather, they appear to be related in a circle of interconnectedness. This is important...

  16. Rehabilitering ved spiseforstyrrelser

    DEFF Research Database (Denmark)

    Lau, Marianne Engelbrecht; Waaddegaard, Mette

    2010-01-01

    Psykiatrisk & psykosocial rehabilitering - en recoveryorienteret tilgang beskriver rehabilitering til mennesker med sindslidelser. Udgangspunktet er en indsats med fokus på den enkeltes egne mål og ressourcer. Bogen bidrager bl.a. med metoder og teoretiske forudsætninger for en national psykiatri...

  17. Neurobiologiske forstyrrelser ved skizofreni

    DEFF Research Database (Denmark)

    Glenthøj, Birte Y; Nordentoft, Merete; Lublin, Henrik

    2008-01-01

    Schizophrenia is a complex disease. A more complete understanding of its neurobiology has been hampered by the fact that most data have been based on studies of patients diagnosed according to either the ICD-10 or the DSM-IV, i.e. patients suffering from pathogenetically different diseases...

  18. Aortahomograftoperationer ved svaer endokarditis

    DEFF Research Database (Denmark)

    Foghsgaard, S.; Kjaergard, H.K.; Bruun, Niels Eske

    2008-01-01

    with an aortic homograft in combination with antibiotics. MATERIALS AND METHODS: 24 patients with either aortic prosthetic valve endocarditis (n = 16) or severe aortic endocarditis (n = 8) were operated with implantation of an aortic homograft at a Danish university hospital from 1997-2006. Staphylococcus...... species were the most common pathogens followed by streptococcus. Intravenous antibiotic therapy was started before surgery and continued for 4-6 weeks. The patients were followed-up for (1/2)-10 years (mean 5 years). RESULTS: 3 patients with prosthetic valve endocarditis died within the first 24 hours...

  19. Neurologiske aspekter ved stammen

    DEFF Research Database (Denmark)

    Mertz, Line Bie; Østergaard, John R

    2006-01-01

    Stuttering is characterised by repetitions, prolongations and pausing while speaking. Researchers have looked for many explanations. However, the cause of stuttering remains unknown. In recent years, structural abnormalities in the speech-related structures of the central nervous system have been...... brought into focus as a cause of stuttering. Research has shown signs of a lateral hemisphere asymmetry, abnormalities in the basal ganglia, dysfunction in the supplementary motor area and/or a dysfunction in the coordination of the cerebellum. This article is a review of this part of the literature...

  20. Bedre produktivitet ved renovering

    DEFF Research Database (Denmark)

    Bertelsen, Niels Haldor

    Det er en udbredt opfattelse, at priserne er for høje, og at kvaliteten er for dårlig i renoveringen. I denne rapport gives en beskrivelse af forsøg på tre ejendomme i Odense, hvor man har undersøgt de forskellige dele i renoveringsprocessen. Der er arbejdet med rollefordelingen, beskrivelsen, fe...

  1. Psykose ved affektive lidelser

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel

    2008-01-01

    Psychosis in affective disorder is prevalent as 15-20% of depressive patients and approximately 50% of manic patients present with psychotic features. Psychosis in conjunction with affective disorder has a poor prognosis. It is particularly so for depression where psychosis is associated...... with an increased risk of recurrence, development of bipolar disorder and suicide. It is still being debated whether these conditions reflect independent illness entities and their relationship to schizoaffective disorder and schizophrenia is also unresolved....

  2. Psykose ved affektive lidelser

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel

    2008-01-01

    Psychosis in affective disorder is prevalent as 15-20% of depressive patients and approximately 50% of manic patients present with psychotic features. Psychosis in conjunction with affective disorder has a poor prognosis. It is particularly so for depression where psychosis is associated...... with an increased risk of recurrence, development of bipolar disorder and suicide. It is still being debated whether these conditions reflect independent illness entities and their relationship to schizoaffective disorder and schizophrenia is also unresolved Udgivelsesdato: 2008/11/10...

  3. Billeddiagnostik ved akut lungeemboli

    DEFF Research Database (Denmark)

    Hess, Søren; Madsen, Poul Henning; Jørgensen, Henrik Boel

    2005-01-01

    and echocardiography in acute pulmonary embolism and identified 562 articles, of which 16 original papers met our inclusion criteria. From these, we concluded that none of the modalities is applicable in every situation. Spiral computed tomography can confirm the diagnosis but cannot rule out subsegmental embolism....... With lung scintigraphy, perfusion imaging alone is probably sufficient and suited to both confirming and ruling out the diagnosis. Echocardiography should be reserved for patients with an emergent need for treatment and cannot rule out the diagnosis. Udgivelsesdato: 2005-Oct-10...

  4. Nitrogenoxidinhalation ved akut lungesvigt

    DEFF Research Database (Denmark)

    Jensen, T H; Henneberg, S W; Heslet, L

    1995-01-01

    Two cases of adult respiratory distress syndrome (ARDS) treated successfully with nitric oxide (NO) inhalation are described. One patient had severe sepsis and the other had trauma induced ARDS. The slow entry criteria for extracorporeal membrane oxygenation (ECMO) was fulfilled in both cases...

  5. Tryghed ved udskrivelse

    DEFF Research Database (Denmark)

    Gryet, Inger Markussen; Kjærsgaard-Andersen, Anne Marie

    Introduction According to international studies, a feeling of security is important for patients when discharge from the hospital. Feeling secure when discharged has been a national focus area in Denmark and national surveys show that about 12% of patients feel insecure when discharged. The nurses...... from a larger group of patients about factors related to the feeling of security and insecurity when discharged from the hospital. Objectives To gain knowledge about which patients feel insecure when discharged and what the reason is for this feeling of insecurity, to get ideas on how to improve...... the feeling of security at discharge for future patients. Methods An electronic questionnaire survey was developed and filled out via iPad before patients discharge from hospital and followed up by telephone interviews with a number of patients. Results 151 patients participated in the questionnaire survey...

  6. Ideudvikling ved kreativ innovation

    DEFF Research Database (Denmark)

    Sejer Jakobsen, Henning; Rebsdorf, S.O.

    og brugbar forståelse af hele skabelsesprocessen. Idestigen med Tanke - Ide - Løsning er hele grundlaget, og med introduktionen til Creative Idea Solution (CIS) gives læseren en konkret model for, hvordan en proces på grænsen af kaos kan blive til en kontrolleret forandringsproces. Det normative...

  7. Ideudvikling ved kreativ innovation

    DEFF Research Database (Denmark)

    Sejer Jakobsen, Henning; Rebsdorf, S.O.

    og brugbar forståelse af hele skabelsesprocessen. Idestigen med Tanke - Ide - Løsning er hele grundlaget, og med introduktionen til Creative Idea Solution (CIS) gives læseren en konkret model for, hvordan en proces på grænsen af kaos kan blive til en kontrolleret forandringsproces. Det normative...... udgangspunkt er garant for at bogen aldrig bliver uvedkommende eller kan afskrives som endnu en publikation med overforbrug af buzzwords. Bogen efterlader læseren med en følelse af lige at være vågnet, og det nyopdagede potentiale skal nu udnyttes systematisk....

  8. Kawasakis syndrom hos voksne

    DEFF Research Database (Denmark)

    Roed, Casper; Skinhøj, Peter

    2009-01-01

    Kawasaki syndrome (KS), which is febrile systemic vasculitis complicated by coronary aneurysms, was initially described in children, but an increasing number of case-reports address adult-KS. The disease seems to be infectious of origin, but the causative agent has not been established. The debut...

  9. Urogenital tuberkulose hos danskere

    DEFF Research Database (Denmark)

    Almasi, Charlotte Elberling; Holm, Mette; Meyhoff, Hans-Henrik

    2002-01-01

    Extrapulmonary tuberculosis is rare in natives of Denmark, who are not exposed to risk factors, such as homelessness and drug or alcohol abuse. Two patients diagnosed with advanced urogenital tuberculosis are reported.......Extrapulmonary tuberculosis is rare in natives of Denmark, who are not exposed to risk factors, such as homelessness and drug or alcohol abuse. Two patients diagnosed with advanced urogenital tuberculosis are reported....

  10. Nogle argumentationsgange hos Habermas

    DEFF Research Database (Denmark)

    Dupont, Søren

    1985-01-01

    Artiklen forholder sig til væsentlige begreber fra Habermas' teori om den kommunikative handlen.......Artiklen forholder sig til væsentlige begreber fra Habermas' teori om den kommunikative handlen....

  11. Hypertension hos gravide

    DEFF Research Database (Denmark)

    Mathiesen, Elisabeth R; Johansen, Marianne; Kamper, Anne Lise

    2009-01-01

    There are four major hypertensive disorders in pregnancy: chronic hypertension, gestational hypertension, preeclampsia and chronic hypertension with superimposed preeclampsia. The indications and efficacy of antihypertensive treatment of the different hypertensive disorders are assessed. Advantages...

  12. Botulisme hos et spaedbarn

    DEFF Research Database (Denmark)

    Nielsen, Allan Bybeck; Nordly, Sannie Brit; Clausen, Marianne Engel

    2010-01-01

    investigation, contaminated food was not found. One particular batch of canned baby food was suspected and recalled from the market, but no contamination was found. The girl had not ingested honey. The condition is rare, but can be very serious and should be kept in mind in cases presenting with the well...

  13. Harepest hos jaeger

    DEFF Research Database (Denmark)

    Edfors, Robert; Smith, Birgitte; Lillebaek, Troels

    2010-01-01

    "Rabbit fever" (Francisella Tularensis) is a rare infection in Denmark. It was first described in Denmark in 1987. It is most likely to affect people who come into close contact with infected animals or ticks, such as hunters, butchers and veterinarians. The diagnosis should be suspected in such ......"Rabbit fever" (Francisella Tularensis) is a rare infection in Denmark. It was first described in Denmark in 1987. It is most likely to affect people who come into close contact with infected animals or ticks, such as hunters, butchers and veterinarians. The diagnosis should be suspected...

  14. Hypertension hos gravide

    DEFF Research Database (Denmark)

    Mathiesen, Elisabeth R; Johansen, Marianne; Kamper, Anne Lise

    2009-01-01

    There are four major hypertensive disorders in pregnancy: chronic hypertension, gestational hypertension, preeclampsia and chronic hypertension with superimposed preeclampsia. The indications and efficacy of antihypertensive treatment of the different hypertensive disorders are assessed. Advantages...... and disadvantages of different classes of antihypertensive drugs during pregnancy and lactation are described....

  15. Syfilis hos gravide

    DEFF Research Database (Denmark)

    Vestergaard, Tine; Ibsen, Hans Henning Windeløv

    2012-01-01

    The incidence of syphilis in Denmark is rising. In 2010, 377 new cases of syphilis were reported, 36 of these cases in women. Since January 1st 2010 all pregnant women are offered an antenatal syphilis test. This resulted in the finding of seven cases of syphilis among pregnant women in 2010....... This article summarises the clinical and serological findings in syphilis and describes the treatment of the disease, with focus on pregnancy and congenital infection....

  16. Lejringsskader hos rygopererede patienter

    DEFF Research Database (Denmark)

    Sestoft, Bodil; Larsen, Birgit; Erlandsen, Mogens

    2009-01-01

    at particular risk of developing positioning-related injuries? MATERIAL AND METHODS: Follow-up study comprising 299 patients. A patient record followed the patient from the day of surgery until discharge. Selected pre-disposing factors related to positioning injuries as well as positioning-related injuries were...

  17. Bilateral akillesseneruptur hos nyretransplanterede

    DEFF Research Database (Denmark)

    Skovgaard, D; Feldt-Rasmussen, B F; Nimb, L

    1996-01-01

    Increased incidence of tendinitis and tendon ruptures is reported in recipients of a kidney transplant. Two cases of bilateral achilles tendon rupture after minimal trauma are described. Tendon ruptures are more frequent in individuals with kidney disease in dialysis or after transplantation...

  18. Laegemiddelinteraktioner hos intensivpatienter

    DEFF Research Database (Denmark)

    Saaby, Lasse; Olesen, Charlotte; Fedder, Jens

    2009-01-01

    INTRODUCTION: The purpose of this study was to investigate the frequency of potential drug-drug interactions (DDIs) within the first 24 hours of admission to an intensive care unit, and to determine which drugs were involved in potential DDIs along with the clinical relevance of the identified DDIs....... METHODS: Drug data from all intensive care patients (n = 102) admitted during a three-month period in the spring 2007 were investigated. Potential DDIs were evaluated using the drug interaction system of Micromedex. RESULTS: Four patients were excluded because their treatment only included one drug....... A total of 98 patients were treated with an average of ten drugs per patient. Among the enrolled patients, we found 242 potential DDIs, corresponding to an average of 2.5 DDIs per patient. The drugs most frequently involved in potential DDIs included antithrombotic drugs, opioids, loop diuretics, ACE...

  19. Lith. vedą̃ = Sl. *vedǫtь̍: the accentuation of the nom. pl. of active participles as further proof of finite origin

    Directory of Open Access Journals (Sweden)

    Marek Majer

    2018-01-01

    Full Text Available The aberrant form of the nom. pl. of Balt. active participles (Lith. vedą̃ etc. has been aptly explained (Cowgill, partly anticipated by Endzelīns as the intrusion of the old finite 3. pl. (< PIE *wedʰonti etc. into the nominal paradigm of the participle. However, it has been unnoticed so far that the accentuation of the form – synchronically completely isolated and unexpected, as the only end-stressed athematic nom. pl. – is also explained by, and therefore corroborates, this theory. The accent corresponds exactly to the PBSl. reconstruction 3. pl. pres. *wedantı̍ (conceivably, although less plausibly, PBSl. *weda̍nti pointed to by Proto-Slavic *vedǫtь̍.

  20. Cerebral blood flow autoregulation in patients with acute bacterial meningitis

    DEFF Research Database (Denmark)

    Møller, Kirsten

    2001-01-01

    Ph.d. afhandlingen omhandler sammenhængen mellem hjernens blodtilførsel (CBF) og middelarterietrykket (MAP) hos patienter med akut bakteriel meningitis. Hos raske er CBF uafhængig af MAP, hvilket kaldes CBF autoregulation. Svækket autoregulation antages at øge risikoen for cerebral hypoperfusion og...... iskæmi under episoder med lavt MAP, og for cerebral hyperperfusion og vasogent ødem ved højt MAP. CBF autoregulationen undersøgtes hos tyve voksne patienter med akut bakteriel meningitis i den tidlige sygdomsfase (... meningitis, men retableres ved klinisk restitution. Autoregulationen kan endvidere delvis retableres ved akut hyperventilation. Fundene har potentiel betydning for valg af supportiv terapi hos patienter med meningitis....

  1. Dömda att leva i skuggan : En kvalitativ intervjustudie om hälsan hos personer med albinism i Rwanda, utifrån begreppen diskriminering, coping och socialt stöd

    OpenAIRE

    Niyonkuru, Elsie Diane

    2016-01-01

    Bakgrund: Oculocutaneous albinism (OCA) är en ärftlig sjukdom som fysiskt, psykiskt och socialt påverkar de drabbade individerna. Okunskap, fördomar och myter om albinism utgör de största orsakerna till den diskriminering som personer med albinism utsatts för särskilt i vissa länder i Afrika söder om Sahara. Syfte: Syftet är att beskriva hälsan hos personer med albinism i Rwanda, utifrån begreppen diskriminering, coping och socialt stöd. Metod: En kvalitativ metod med induktiv ansats ligger t...

  2. 'HeART of Stroke (HoS)', a community-based Arts for Health group intervention to support self-confidence and psychological well-being following a stroke: protocol for a randomised controlled feasibility study.

    Science.gov (United States)

    Ellis-Hill, Caroline; Gracey, Fergus; Thomas, Sarah; Lamont-Robinson, Catherine; Thomas, Peter W; Marques, Elsa M R; Grant, Mary; Nunn, Samantha; Cant, Robin P I; Galvin, Kathleen T; Reynolds, Frances; Jenkinson, Damian F

    2015-08-04

    Over 152,000 people in the UK have strokes annually and a third experience residual disability. Low mood also affects a third of stroke survivors; yet psychological support is poor. While Arts for Health interventions have been shown to improve well-being in people with mild-to-moderate depression post-stroke, their role in helping people regain sense of self, well-being and confidence has yet to be evaluated. The main aim of this study is to explore the feasibility of conducting a pragmatic multicentre randomised controlled trial to assess the effectiveness and cost-effectiveness of an Arts for Health group intervention ('HeART of Stroke' (HoS)) for stroke survivors. HoS is a 10-session artist-facilitated group intervention held in the community over 14 weeks. It offers a non-judgemental, supportive environment for people to explore sense of self, potentially enhancing well-being and confidence. Sixty-four people, up to 2 years post-stroke, recruited via secondary care research staff or community stroke/rehabilitation teams in two UK centres will be randomised to either HoS plus usual care or usual care only. Self-reported outcomes, measured at baseline and approximately 5 months postrandomisation, will include stroke-related, well-being, mood, self-esteem, quality of life and process measures. Analyses will focus on estimating key feasibility parameters (eg, rates of recruitment, retention, intervention attendance). We will develop outcome and resource use data collection methods to inform an effectiveness and cost-effectiveness analysis in the future trial. Interviews, with a sample of participants, will explore the acceptability of the intervention and study processes, as well as experiences of the HoS group. National Health Service (NHS), Research and Development and University ethical approvals have been obtained. Two peer-reviewed journal publications are planned plus one service user led publication. Findings will be disseminated at key national conferences

  3. Expression and function of the ACE2/angiotensin(1-7)/Mas axis in osteosarcoma cell lines U-2 OS and MNNG-HOS.

    Science.gov (United States)

    Ender, Stephan Albrecht; Dallmer, Andrea; Lässig, Florian; Lendeckel, Uwe; Wolke, Carmen

    2014-08-01

    The renin-angiotensin-system (RAS), via its classical angiotensin-converting enzyme (ACE)/angiotensin II/angiotensin II type 1 receptor (AT1R)-axis, is associated with proliferation and metastasis of numerous types of solid tumor. AT1R blockers reduce tumor volume and decrease liver and lung metastasis in murine models of osteosarcoma. Expression and function of the alternative ACE2/Ang(1-7)/Mas axis in osteosarcoma is yet to be studied. In the present study, the basic and interleukin (IL)-1β-stimulated expression of components of this alternative RAS axis were analyzed and the impact of Mas on proliferation and/or migration of U-2 OS and MNNG-HOS osteosarcoma cells was studied. Quantitative polymerase chain reaction revealed that the two cell lines expressed the Ang(1‑7)-generating peptidases ACE2, neutral endopeptidase 24.11 and prolyl-endopeptidase together with the putative receptor for Ang(1-7), Mas. IL-1β provoked an induction of Mas mRNA and protein expression which was associated with a reduction of proliferation and migration. By contrast, small interfering RNA-mediated knockdown of Mas expression led to increased cell proliferation. In conclusion, osteosarcoma cells express a functional active alternative ACE2/Ang(1-7)/Mas axis. The induction and reinforcement of this axis may be beneficial for the treatment of osteosarcoma by reducing growth and preventing cancer metastasis. These effects may be achieved directly by the administration of Mas agonists or, indirectly, via blocking the classical AngII RAS axis via ACE inhibitors or AT1R antagonists.

  4. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-09-09 to 2010-09-27 in response to the Deepwater Horizon oil spill event (NODC Accession 0069071)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-09-09 to 2010-09-27 in response to the Deepwater...

  5. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-08-26 to 2010-09-03 in response to the Deepwater Horizon oil spill event (NODC Accession 0069070)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-08-26 to 2010-09-03 in response to the Deepwater...

  6. Chemical and physical oceanographic profile data collected from CTD casts aboard the HOS Davis in the Gulf of Mexico from 2010-08-13 to 2010-08-22 in response to the Deepwater Horizon oil spill event (NODC Accession 0069069)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and physical oceanographic profile data were collected aboard the HOS Davis in the Gulf of Mexico from 2010-08-13 to 2010-08-22 in response to the Deepwater...

  7. God vård och användning av digitala hjälpmedel:Föreställningar hos äldre och vårdpersonal

    OpenAIRE

    Harrefors, Christina

    2011-01-01

    Det övergripande syftet med avhandlingen var att belysa föreställningar om god vård och användning av digitala hjälpmedel hos äldre personer och vårdpersonal. Föreställningar förändras kontinuerligt beroende på teknikutveckling och socio-politiska förändringar i samhället. Den forskning som presenteras i denna avhandling omfattar data som belyser detta perspektiv samt efterföljande analys och tolkning.I delstudie I och II, genomfördes individuella intervjuer med tolv äldre, friska par i deras...

  8. Perifert ameloblastom

    DEFF Research Database (Denmark)

    Reibel, Jesper; Jensen, Jesper Bak

    2016-01-01

    Baggrund – Perifert ameloblastom er en sjælden ekstra-ossøs variant af det klassiske centrale ameloblastom. Tilstanden ses oftest hos midaldrende eller ældre. Der ses hyppigere forekomst hos mænd, og det hyppigst afficerede område er mandiblens præmolarområde. Klinisk ses en langsomt voksende sme...... ameloblastomer behandles med kirurgisk excision. Ved kontrol et år postoperativt var der ingen tegn på recidiv....

  9. Case report - curved femoral osteotomy for management of medial patellar luxation

    DEFF Research Database (Denmark)

    Allpass, Maja; Miles, James Edward

    2015-01-01

    Medial patellaluxation kan forårsages af femoral varus hos hund. Førhen har patienter med excessiv femoralvarus været korrigeret ved en lateralt placeret femoral kile-ostektomi. Her præsenteres en case, hvor en buet osteotomi blev anvendt til behandling af medial patellaluxation.......Medial patellaluxation kan forårsages af femoral varus hos hund. Førhen har patienter med excessiv femoralvarus været korrigeret ved en lateralt placeret femoral kile-ostektomi. Her præsenteres en case, hvor en buet osteotomi blev anvendt til behandling af medial patellaluxation....

  10. Kønsforskelle ved autoimmune sygdomme illustreret ved reumatoid artritis

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Dreyer, Lene

    2007-01-01

    for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling....

  11. Forbedret prognose ved letkædenefropati ved myelomatose

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Larsen, Thomas; Marcussen, Niels

    2012-01-01

    A 64 year-old woman with acute renal failure and cast nephropathy due to excessive production of lambda free light chains received chemotherapy (using bortezomib and dexamethason) and haemodialysis with a high cut off-filter. The concentration of free light chains was markedly reduced after...

  12. Fagligt Forum ved en skillevej

    DEFF Research Database (Denmark)

    Bjerg, Claus

    2008-01-01

    Med cvu-bibliotekernes overgang til professionshøjskoler ændres det biblioteksfaglige landskab. Det har Fagligt Forum taget konsekvensen af og nedlægger sig selv i løbet af 2000......Med cvu-bibliotekernes overgang til professionshøjskoler ændres det biblioteksfaglige landskab. Det har Fagligt Forum taget konsekvensen af og nedlægger sig selv i løbet af 2000...

  13. Udfordringer ved undervisning i enzymer

    DEFF Research Database (Denmark)

    Skriver, Karen; Dandanell, Gert; von Stemann, Jakob Hjorth

    2015-01-01

    Enzymer er et centralt emne i biokemiundervisning. Det forudsætter og anvender grundlæggende viden inden for og kompetencer i kemi og matematik. Artiklen undersøger hvilke forståelsesvanskeligheder og udfordringer der er knyttet til dette område, såvel som virtuelle øvelsers potentiale i denne ko...

  14. Flankesmerter ved nyre- og uretersten

    DEFF Research Database (Denmark)

    Pedersen, Katja Venborg; Drewes, Asbjørn Mohr; Osther, Palle Jørn Sloth

    2011-01-01

    with recurrent stones, the colics may be more intense due to sensitisation of the nervous system. Furthermore, painful diseases in the reproductive organs can enhance stone colics. Non-steroidal anti-inflammatory drugs are the first choice for stone colics because they act by reducing the renal pelvic pressure.......Flank pain is common and often associated with stone colics. Similar pain characteristics can, however, be observed in other diseases. Stone colics have all the characteristics of visceral pain. The pain is diffuse, often referred to the body wall and accompanied by autonomic reflexes. In patients...

  15. Kolorektal cancerudvikling ved colitis ulcerosa

    DEFF Research Database (Denmark)

    Kallesøe, Jane; Langholz, E.; Frisch, Morten

    2010-01-01

    Ulcerative colitis (UC) is believed to carry a predisposition to colorectal cancer (CRC) development. International clinical guidelines suggest that UC patients should have a colonoscopy performed every year or up to every third year from approximately eight years after diagnosis for early...

  16. Monitering af kromudledningen ved Qaqortoq

    DEFF Research Database (Denmark)

    Glahder, C.

    the waste water at the tannery and to dis-charge it continuously in order to reduce possible acute toxic impacts of the environment, to test the acute toxicity of the discharge water, to monitor the environment around Great Greenland in a similar study, e.q. every third year, and to study excretion...... analysed by Great Greenland and DMU, AM, respectively, with the use of two different methods, and no significant differences were found in chromium concentrations. This result was found also in 1991. The chromium concentration in the waste water batches of 3-5 m3 are 0.5-0.7 g/l. It is recommended to treat......, an increase in the impacted area, and an increase in chromium discharge (from 200 to 312 kgs per year (1995) and 229 kgs per year (1997)). There seems to be no health risk to ingest relatively large quantities of blue mussels from the impacted area around the tannery. Nine samples of discharge water were...

  17. Nye metoder ved gastrointestinal endoskopi

    DEFF Research Database (Denmark)

    Stigaard, Trine; Meisner, Søren

    2010-01-01

    The development of diagnostic and therapeutic flexible endoscopy is vivid. This article describes some of the most recent diagnostic techniques: Narrow Band Imaging, Fujinon Intelligent Color Enhancement, Autofluorescence Imaging, Optical Coherence Tomography, Confocal Laser Endomicroscopy. Liter...

  18. Bag ved skyerne skinner solen

    DEFF Research Database (Denmark)

    Zobbe, Henrik

    2012-01-01

    På langt sigt skinner solen på erhvervet. De globale udfordringer er store, og landbruget og fødevareindustrien står helt centralt placeret på løsningsdagsordenen......På langt sigt skinner solen på erhvervet. De globale udfordringer er store, og landbruget og fødevareindustrien står helt centralt placeret på løsningsdagsordenen...

  19. Usikkerhed om behandlingsstrategien ved tymomer

    DEFF Research Database (Denmark)

    Abildgaard, Julie; Pappot, Helle; Petersen, Peter Meidahl

    2012-01-01

    of age. Because of the rarity of thymomas, lack of uniformity in treatment has been a major problem over the years. Therefore, international collaborations have been established, and national oncological centralisation of management has been arranged in order to improve the treatment and prognosis....

  20. Neurobiologien ved borderline-personlighedsforstyrrelse

    DEFF Research Database (Denmark)

    Simonsen, Erik; Andersen, Rune

    2012-01-01

    Borderline personality disorder (BPD) is a severe psychiatric disorder characterised by instability of affect regulation, impulse control, interpersonal relationships, and self-image. The aim of this status article is to provide a brief overview of the neurobiological underpinnings of the core di...... dimensions in BPD, as well as of the potential clinical implications. The latest results from genetic, endocrinologic, neuropsychologic, and neuroimaging research in identifying the dysfunctional neurobiological systems that could play a role in diathesis to BPD are presented....

  1. Neurobiologien ved borderline-personlighedsforstyrrelse

    DEFF Research Database (Denmark)

    Andersen, Rune; Simonsen, Erik

    2012-01-01

    Borderline personality disorder (BPD) is a severe psychiatric disorder characterised by instability of affect regulation, impulse control, interpersonal relationships, and self-image. The aim of this status article is to provide a brief overview of the neurobiological underpinnings of the core...

  2. Genetisk udredning ved infantile spasmer

    DEFF Research Database (Denmark)

    Hansen, Lars Kjærsgaard; Ousager, Lilian Bomme; Møller, Rikke Steensbjerre

    2012-01-01

    Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH...

  3. Fordele og ulemper ved forbrugergenetik

    DEFF Research Database (Denmark)

    Christiansen, Camilla Worm; Gerdes, Anne-Marie Axø

    2017-01-01

    Direct-to-consumer genetic tests are sold over the internet to consumers all over the world - including Denmark. No regulation of these tests has been introduced neither in Denmark nor in Europe, even though they have been on the market since 2007. Such tests have several advantages, but indeed a...

  4. Problemer ved skift af antipsykotika

    DEFF Research Database (Denmark)

    Maltesen, Henrik Rasmus; Lublin, Henrik K F

    2012-01-01

    Most patients with schizophrenia switch antipsychotics (APs) either due to lack of efficacy or due to side effects. Changing AP, especially switching from clozapine, may lead to deterioration in the patient's condition because of pharmacodynamic differences between the existing and the new AP. A ...

  5. Genetisk udredning ved infantile spasmer

    DEFF Research Database (Denmark)

    Hansen, Lars Kjærsgaard; Ousager, Lilian Bomme; Møller, Rikke Steensbjerre

    2012-01-01

    Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH as the fi......Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH...

  6. Telomerers rolle ved aldersbetingede sygdomme

    DEFF Research Database (Denmark)

    Bendix, Laila; Kølvraa, Steen

    2010-01-01

    Telomeres are specialized DNA structures, protecting the ends of linear chromosomes. The association between telomeres and cellular aging is well-established, and it has been shown that there is a negative correlation between telomere length and chronological age for many types of human tissue. O...

  7. Psykosociale aspekter ved dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E; Stenager, E N; Knudsen, Lone

    1995-01-01

    Using multiple sclerosis as a model, it is demonstrated how a chronic neurological disorder has psychosocial consequences during the period between onset and diagnosis, at the time of diagnosis, and in the post-diagnostic period. The impact of the disorder on self-esteem, civil status, habitation...

  8. Pneumocystepneumoni ved behandling med infliximab

    DEFF Research Database (Denmark)

    Josephson, Maria Eklund; Kristensen, Lena Hagelskjaer; Andersen, Vibeke

    2008-01-01

    The treatment of ulcerative colitis has improved since the appearance of Tumor Necrosis Factor (TNF)-alpha inhibitors. However, the use of TNF-alpha inhibitors increases the risk of opportunistic infections. We describe two cases of Pneumocystis jiroveci pneumonia during infliximab therapy...... for active ulcerative colitis. They were successfully treated with sulfametoxazole/trimetroprim. High awareness of P. jiroveci pneumonia in patients who develop pulmonary symptoms with hypoxia during TNF-alpha modulator therapy is recommended....

  9. Computertomografi anvendt ved retsmedicinske obduktioner

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Christoffersen, Søren

    2008-01-01

    tilgængelige for obduktion, og tillader undersøgelse af brud og indre organer, som de ser ud in situ. CT giver dokumentation i digital form, som let kan opbevares og kopieres, og som tillader fornyet bedømmelse, og giver fotos, som er æstetisk mere acceptable til retsligt brug end obduktionsfotos. CT kan...

  10. Biologiske behandlingsmuligheder ved Graves' oftalmopati

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Hegedüs, Laszlo

    2008-01-01

    The current medical treatment options for Graves' ophthalmopathy (GO) are unsatisfactory. Recent treatment of GO patients with the B-lymphocyte depleting monoclonal antibody rituximab or with the anti-tumor necrosis factor-alpha agents etanercept and infliximab has shown promising results. We...... discuss the use of these and other biological agents targeting B lymphocytes, T-lymphocyte interaction with antigen-presenting cells, or cytokines in the future treatment of GO....

  11. Kirurgisk behandling ved lokalavanceret pancreascancer

    DEFF Research Database (Denmark)

    Fristrup, Claus Wilki; Pless, Torsten; Hovendal, Claus

    2009-01-01

    Treatment of patients with locally advanced pancreatic cancer remains a challenge, and the exact role of surgery with vascular resection remains unclear. Several studies on selected patient populations have addressed the problem, but with varying results. Although venous resection may be performed...... without increased morbidity and mortality, the majority of studies found no improved long-term survival when compared to oncological treatment. Udgivelsesdato: Nov-9...

  12. Biologiske behandlingsmuligheder ved Graves' oftalmopati

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Hegedüs, Laszlo

    2008-01-01

    The current medical treatment options for Graves' ophthalmopathy (GO) are unsatisfactory. Recent treatment of GO patients with the B-lymphocyte depleting monoclonal antibody rituximab or with the anti-tumor necrosis factor-alpha agents etanercept and infliximab has shown promising results. We...

  13. Ekstraintestinale manifestationer ved inflammatorisk tarmsygdom

    DEFF Research Database (Denmark)

    Larsen, Signe; Bendtzen, Klaus; Nielsen, Ole Haagen

    2009-01-01

    dermatological manifestations, while episcleritis, iridocyclitis and uveitis are common ophthalmological complications. Conventional drugs and biologicals have proven effective in the treatment of several of the manifestations, including peripheral arthritis, pyoderma gangraenosum and episcleritis...

  14. Behandling ved tidlig Hodgkin's sygdom

    DEFF Research Database (Denmark)

    Specht, L K; Carde, P; Mauch, P

    1993-01-01

    indicate that we still do not definitively know whether or not the early addition of prophylactic chemotherapy improves survival. Arguments in favour of early chemotherapy are: that laparotomy may be avoided, that radiation fields and doses may perhaps be reduced, and that the stress of experiencing......In early stage Hodgkin's disease the optimal choice of treatment is still an unresolved issue. Twenty-two randomized trials of radiotherapy alone versus radiotherapy plus combination chemotherapy have been carried out world-wide. The preliminary results of a global meta-analysis of these trials...... a relapse is avoided in many patients. The major argument against early chemotherapy is: that by careful staging and selection of patients and by careful radiotherapy techniques the number of patients exposed to potentially toxic chemotherapy may be kept at a minimum. Recently, trials have been carried out...

  15. Nye terapeutiske styringsmuligheder ved leukaemi

    DEFF Research Database (Denmark)

    Jensen, A W; Hokland, P; Jørgensen, H

    1992-01-01

    Investigations on the configuration of immunoglobulin (Ig) and T-cell receptor (TCR) genes have become more and more widespread. Through these methods it is possible to identify malignant clones, which by a transforming event have been blocked in further differentiation but continued to proliferate....... Such clonal expansions can be verified by the Southern Blotting procedure as differences in molecular weight between normal and rearranged DNA fragments. In the lymphatic disorders it is possible to assign the malignant clone to B cell lineage by rearrangement in the immunoglobulin light chain gene, while...... heavy chain and T-cell receptor genes do not show consistency in lineage restriction. In a study on AML patients with solitary expression of the T-cell marker CD7 we have identified a similarity in TCR beta and delta gene configurations, indicating a correlation between etiology and genetic pattern...

  16. Det ved vi om Feedback

    DEFF Research Database (Denmark)

    Christensen, Vibeke; Bærenholdt, Jørgen

    Præsentation af forskningsviden om feedback i forskellige personkonstellationer i undervisningen: Feedback fra lærer til elev, fra elever til lærer, fra elev til elev og elevens eget arbejde med feedback til sig selv. De præsenterede forskningsresultater er udvalgt dels inden for en kognitivistisk...

  17. Nye metoder ved gastrointestinal endoskopi

    DEFF Research Database (Denmark)

    Stigaard, Trine; Meisner, Søren

    2010-01-01

    The development of diagnostic and therapeutic flexible endoscopy is vivid. This article describes some of the most recent diagnostic techniques: Narrow Band Imaging, Fujinon Intelligent Color Enhancement, Autofluorescence Imaging, Optical Coherence Tomography, Confocal Laser Endomicroscopy. Liter....... Literature was found through searches on PUBMED and written information from Olympus, Fujinon and Pentax. Which techniques will be used in the future? Will optical biopsy soon be possible? We need more controlled studies....

  18. Dødsulykker ved bygningsbrande

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Gregersen, Markil Ebbe Gregers; Sabroe, Svend

    1998-01-01

    %) and accidents with candles (9%). The largest risk groups were chronic alcoholics, handicapped and elderly people. In conclusion, warnings should be issued against smoking in bed and use of loose-fitting clothing while cooking on an open fire. Protective aprons and devices for use while smoking, self...

  19. Perioperativ vaeskebehandling ved perforeret ulcus

    DEFF Research Database (Denmark)

    Bjerre, Catherine Collin; Holte, Kathrine

    2009-01-01

    : Retrospective survey of 45 consecutive patients operated for perforated ulcers over a 3-year period between 1 January 2003 and 31 December 2005 in the surgical department of a university hospital. RESULTS: Data that would permit rational fluid therapy are not being collected on a regular basis. Fluid balance...... to 41 patients (87%) range 0-4,500 ml).CONCLUSION: Both the preoperative fluid management and the postoperative monitoring of the fluid balance are suboptimal and should be optimized. Individualized (goal-directed) fluid administration aiming at optimizing the oxygen supply to the peripheral tissues...

  20. Dilateret kardiomyopati hos en amfetaminmisbruger

    DEFF Research Database (Denmark)

    Svendsen, Mathias Tiedemann; Lambrechtsen, Jess

    2011-01-01

    The patient presented himself at the primary practitioner with dyspnoea and chest pain, and was initially misdiagnosed as having pneumonia. Two weeks later the patient developed universal oedema and was hospitalized. Echocardiography showed dilated cardiomyopathy. The initial diagnosis was delayed...

  1. Behandling af astma hos gravide

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least ...... due to suboptimal adherence with controller therapy and pregnant women's concerns about harmful effects of medication on the fetus. This review provides an update on the safety of asthma medication during pregnancy, based on recent clinical studies and international guidelines.......Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least...

  2. Delirium hos kritisk syge patienter

    DEFF Research Database (Denmark)

    Strøm, Thomas; Pande-Rolfsen, Guri; Hagen, Christine

    2009-01-01

    Interest in and the quantity of publications on delirium in critically ill patients have grown increasingly over the last decade. Critically ill patients have traditionally been sedated to facilitate mechanical ventilation. This practice impeded the recognition of delirium in the critically ill...... patients, and consequently the disorder was underdiagnosed. Delirium in the critically ill patients is associated with increased morbidity and mortality. Less sedation, guided by protocols with daily wake up trials, and validated delirium scoring systems, have improved the opportunities to diagnose...... and monitor delirium in the critically ill patients. Udgivelsesdato: 2009-Oct-19...

  3. Diagrammer hos Pierce og Deleuze

    DEFF Research Database (Denmark)

    Busk, Malene

    2006-01-01

    Artiklen omhandler to forskellige begreber om diagrammet, nemlig Pierces og Deleuzes. De definerer udfra to meget forskellige udgangspukter begge diagrammet som kreativt redskab......Artiklen omhandler to forskellige begreber om diagrammet, nemlig Pierces og Deleuzes. De definerer udfra to meget forskellige udgangspukter begge diagrammet som kreativt redskab...

  4. Peripartum kardiomyopati hos overvaegtig gravid

    DEFF Research Database (Denmark)

    Kielgast, Urd Lynge; Schierbeck, Louise; Dümcke, Christine

    2009-01-01

    Peripartum cardiomyopathy (PPCM) is a rare, but life-threatening cardiac disorder which complicates pregnancy. However, the classical symptoms of heart failure can be masked - especially in obese women. Here, we present a case report of PPCM complicated with vitamin-D deficiency in a severely obese...

  5. Endoteldysfunksjon hos barn og unge

    OpenAIRE

    Røysland, Ragnhild

    2006-01-01

    This review headlights the subject endothelial dysfunction in the paediatric population. Endothelial dysfunction is recognized as en independent risk factor of atherosclerotic disease. Even before macroscopic evidence of the disease, endothelial dysfunction may be present. It is believed that one major mechanism underlying the phenomenon of endothelial dysfunction is decreased bioavailability of endothelium-derived nitric oxide (NO), due to reduced production or increased degradation. This ar...

  6. Demenslidelser hos aeldre tyrkiske indvandrere

    DEFF Research Database (Denmark)

    Rosenbaum, Bent; Kristensen, Majken; Schmidt, John

    2008-01-01

    The health condition in a population of elderly Turkish immigrants is investigated with special focus on dementia conditions. The possibility to use the screening test Mini Mental State Examination (MMSE) in relation to the investigated population is evaluated as well as their future need...

  7. Kommentarer til SNS, Glycine max (A2704-12), vurdering af konsekvenserne ved at importere og anvende sojabønnerne på den måde, det er beskrevet i ansøgningen, modtaget 20-02-2006, deadline 01-05-2006

    DEFF Research Database (Denmark)

    Kjellsson, Gøsta; Damgaard, Christian; Strandberg, Morten Tune

    2006-01-01

    de klimatiske forhold udelukker dette. En markedsføring af sojabønnen kan derfor ikke have nogen uønskede økologiske konsekvenser i Danmark. I dyrkningsområderne i Sydeuropa kan der ved uheld ske en iblanding af GM-sojafrø i frø til udsæd af ikke-GM soja. En eventuel tilfældig spredning af GM-soja...

  8. Unbiased estimates of number and size of rat dorsal root ganglion cells in studies of structure and cell survival

    DEFF Research Database (Denmark)

    Lamm, Trine Tandrup

    Neurodegenerative sygdomme er karakteriseret ved tab af nervefibre og nervecellelegemer. Tilstande med fysiske eller toksikologiske beskadigelser af de primære sensoriske nerveceller hos rotten har ofte været anvendt som model for forståelse af de processer, der fører til celledød eller -overleve...

  9. Boligen som ramme for trivsel

    DEFF Research Database (Denmark)

    Knudstrup, Mary-Ann; Møller, Kurt

    2008-01-01

    De boligmæssige rammer som ældre bor i, har betydning for deres trivsel. I kapitlet fremlægges forskningsbaseret viden om, hvordan beslutningsprocessen ved plejeboligbyggeri finder sted, og herunder hvordan de boligmæssige forholds betydning for trivslen hos ældre mennesker indgår i beslutningern...

  10. Physical Activity Patterns in Patients with Alcohol Use Disorder

    DEFF Research Database (Denmark)

    Sari, Sengül; Bilberg, Randi Marie; Nielsen, Anette Søgaard

    2017-01-01

    Tværsnitsundersøgelsen beskriver de deltagende alkoholpatienters fysiske aktivitetsniveau ved behandlingsstart. Med denne undersøgelse havde vi til formål at opnå viden om sundhedsadfærden hos behandlingssøgende mennesker med et alkoholmisbrug. Hertil blev det internationale spørgeskema om fysisk...

  11. HPV-vaccination af drenge - Effekt på anogenitale infektioner og cancere

    DEFF Research Database (Denmark)

    Roed, Michelle S.; Nielsen, Anni Brit Sternhagen; Aabenhus, Rune Munck

    2013-01-01

    HPV-vaccination tilbydes alle piger, men skal HPV-vaccinationen også tilbydes drenge? Det undersøger forfatterne i denne artikel ved at kigge litteraturen igennem. Konklusionen er, at der nok også er effekt på en række af de HPV-relaterede sygdomme hos drenge/mænd. Der mangler imidlertid fortsat...

  12. Pædodontisk parodontologi

    DEFF Research Database (Denmark)

    Nørregaard, Marie-Louise Milvang; Kongstad, Johanne; Poulsen, Anne Havemose

    2015-01-01

    Pædodontisk parodontologi En tidlig alder for sygdomsdebut, høj sygdomsprogression, fravær af systemisk sygdom og involvering af flere tænder med et karakteristisk mønster for tab af den alveolære knogle er vigtige diagnostiske elementer ved den aggressive marginale parodontitis. Hos børn og unge...

  13. REGULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN COLLAGENOUS COLITIS

    DEFF Research Database (Denmark)

    Andresen, Lars

    2004-01-01

    ulcerøs colitis, der er karakteriseret ved en kronisk recidiverende, sårdannende inflammation af kolorektalslimhinden. I nærværende sammenlignende studie er ekspressionen af iNOS og aktiviteten af enzymets transkriptionsfaktor, nukleær faktor-kappa B (NF-B), i slimhindebiopsier fra colonslimhinden hos...

  14. Eksistens i Hermann Schmitz' 'nye fænomenologi'

    DEFF Research Database (Denmark)

    Frølund, Sune

    2017-01-01

    /affektive ramtheder”. Derfor bliver – foruden kroppen – også følelseslæren en vigtig dimension af Schmitzs fænomenologi. Schmitz er langsomt ved at vække interesse hos filosofferne, med Gernot Böhme og Peter Sloterdijk som ambassadører. Men blandt ’praktikere’, dvs. psykologer, fysioterapeuter, læger, psykoterapeuter...

  15. Fatal Klippel-Trenaunay syndrome in a child with pulmonary embolism

    DEFF Research Database (Denmark)

    Pedersen, Rie Skovgaard; Hedelund, Lene; Poulsen, Lone H

    2013-01-01

    Klippel-Trénaunays syndrom (KTS) er en sjælden, medfødt sygdom, der er kendetegnet ved venøse malformationer (VM), kutane kapillære malformationer og overvækst af bløddele og/eller knogler [1]. Forekomst af hyperkoagulabilitet, trombosering og lungeemboli er tidligere beskrevet hos patienter med ...

  16. Adoption, psykiske lidelser og kriminalitet blandt 15-27 årige. En landsomfattende sammenlignelig registerbaseret undersøgelse af adopterede og af stedbørn sammenlignet med ikke-adopterede i Danmark

    DEFF Research Database (Denmark)

    Laubjerg, Merete; Petersson, Birgit

    2010-01-01

    adopterede > 12 mdr. samt stedbørn har 3-4 gange højere risiko. Derimod er 'oprindelse' en risikofaktor for kriminalitet for internationalt adopterede og for indvandrere. Alder ved adoption, kontakt til psykiatrien og 'bor ikke hos forælder' er risiko for dom og recidiv. Drenge får i langt højere grad end...

  17. Brændeovn med autopilot

    DEFF Research Database (Denmark)

    Illerup, Jytte Boll

    2013-01-01

    Ved at sætte brændeovnen på autopilot opnår man en bedre energiudnyttelse og en markant reduktion af luftforurenende stoffer. Automatisk styring af brændeovnen giver lige så lave emissioner hos forbrugeren som på testinstitutter, viser et forskningsprojekt mellem den jyske brændeovnproducent HWAM...

  18. Food as Social Markers: A Copenhagen Hospital 1800

    DEFF Research Database (Denmark)

    Hyldtoft, Ole

    2008-01-01

    Artiklen handler om de tydelige sociale markeringer ved valget af mad og drikke hos de enkelte samfundsgrupper i København omkring 1800. Hovedgrundlaget består af bevarede spisereglementer for ammer, jordemoderelever og fire typer af patienter på Den kgl. Fødsels- og Plejestiftelse i København i...

  19. Tuberkulose forårsaget af Mycobacterium africanum

    DEFF Research Database (Denmark)

    Bek, Dorte; Kjeldsen, Marianne Kirstine; Hansen, Nikolaj Friis

    2010-01-01

    Tuberkulose (TB) forårsages af patogene arter fra Mycobacterium tuberculosis komplekset (MTBC) og har en incidens på cirka 7/100.000 i Danmark. På mistanke om TB hos en akut indlagt 40 årig afrikansk mand initieredes anti-TB behandling. Efter 13 timers indlæggelse afgik patienten ved døden. Fra...

  20. Exercise Training in Stable Heart Transplant recipients

    DEFF Research Database (Denmark)

    Dall, Christian Have

    Afhandlingen består af to forsøg, et randomiseret crossover forsøg der undersøger effekten af træning på hjertetransplanterede, samt et klinisk forsøg der undersøger akut blodtryksstigning ved styrketræning hos hjertetransplanterede, hjertesvigtspatienter, og patienter med iskæmisk hjertesygdom. ...

  1. Hvilke patienter kan ses af sygeplejersker

    DEFF Research Database (Denmark)

    Nørøxe, Karen Busk; Moth, Grete; Vedsted, Peter

    2014-01-01

    patienter, til en sygeplejerske. Hos patienterne er det især mænd og de yngre, der ser konsultation ved en sygeplejerske som en mulighed. Selvom kronisk sygdom er et af de områder, hvor sygeplejersker i stigende grad involveres i almen praksis, synes kronisk sygdom dog ikke at have afgørende betydning...

  2. Praksis som læringsmetode i ingeniørutdanningen – erfaringer fra ingeniørstudiet i undervannsteknologi - drift og vedlikehold ved Høgskolen i Bergen (HiB

    Directory of Open Access Journals (Sweden)

    Laila Linde Lossius

    2014-05-01

    Full Text Available Norsk ingeniørutdanning har blitt kritisert for å være for teoretisk. Næringslivets hovedorganisasjon (NHO m.fl. startet derfor prosjektet «Lærlingeordning i høyere utdannelse». Høgskolen i Bergen dro nytte av erfaringene derfra, og i 2007 – da bachelorstudiet i undervannsteknologi startet – var forutsetningen at studiet skulle ha stor praksisandel og mye kontakt med lokalt næringsliv. Studiet har blitt Norges mest etterspurte treårige ingeniørstudium. Frafallet har vært lavere enn ved andre ingeniørstudier. Studiet har inneholdt flere praksisformer, hvorav bacheloroppgave i bedrift, ingeniørpraksis og verkstedpraksis ble regnet som de mest utbytterike ut fra svar i spørreundersøkelsene. 72 % av studentene anså praksis som en viktig årsak til at de søkte. Faglig interesse og utsikt til gode jobber var dog viktigst. 71 % av studentene opplevde at praksis underveis ville gjøre dem til bedre ingeniører, mens 55 % mente det hadde innvirkning på at de fullførte studiet. Praksisbedriftene har tjent ved bedret rekruttering, de største opptil 0,7 ansatt per praksisplass. Praksisorganisering er krevende, og kvalitetssikring og oppfølging er viktig for å få et godt resultat. Bedriftsnettverk er gode støttespillere, men skolen må også avsette nok ressurser til arbeidet. Siden skader kan skje i industrien, må forsikringsordninger av studenter i praksis settes på den politiske agendaen slik at regelverket kan endres. Summary Norwegian engineering studies has been criticized of being too theoretical. Bergen University College used experiences from the project “Apprenticeship in higher education” when starting the engineering program in Subsea technology in 2007. Much practice and contact with local industry was requested. The program has become popular and dropout is lower than in comparable programs. Student surveys revealed the most rewarding practice to be a company-based Bachelor thesis, engineer internships and

  3. Fremre korsbåndskade og utvikling av sekundær artrose

    OpenAIRE

    Holm, Stine

    2013-01-01

    Oppgaven er en blanding av et litteraturstudie og en kohortestudie. I litteraturstudien har jeg sett på hva fremre korsbånd og artrose er, og hvilke risikofaktorer som kan bidra/progrediere utvikling av artrose hos korsbåndsopererte. I kohortestudien har jeg og veilederen sett på forekomsten av artrose hos korsbåndsopererte- 10-20 år etter ACL rekonstruksjon. Ved hjelp av røntgen og klinisk undersøkelse vurderte vi tidligere korsbåndsopererte og grad av artroseforandringer. Vi så også på hvor...

  4. Resultater efter primaer stapedotomi ved otosklerose

    DEFF Research Database (Denmark)

    Wanscher, Jens; Grøntved, Aksel; Faber, Christian

    2009-01-01

    performed using small-fenester-technique in the period 1996-2005. Five experienced ear surgeons performed the operations. The surgeons were still in the learning phase with regard to otosclerosis surgery. RESULTS: A significant improvement was found regarding the air-conduction pure tone average (PTA) (52.......8 dB to 31.4 dB), the bone conduction PTA (25.2 dB to 23,1 dB), air-bone gap (27.6 dB to 8.3 dB), and the speech reception threshold (44.8 dB to 22.5 dB). One operation (0.6%) resulted in severe sensory-neural hearing loss, while other types of complications were seen after 7,2% of the operations...

  5. Katetervejledt trombolyse ved perifer arteriel okklusion

    DEFF Research Database (Denmark)

    Lindholt, J S; Holt, G; Sandermann, J

    2001-01-01

    (TOPAS and STILE) have serious selection bias, which makes generalisation difficult. Other studies have incomparable data and thus meta-analysis is impossible. Consequently, a recent consensus document cannot recommend an agent or principle of infusion. Thrombolysis of late, but transitory (

  6. Genetik og stressende livsbegivenheder interagerer ved depression

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Bukh, Jens Otto Drachmann

    2013-01-01

    to a lesser extent are preceded by stressful life events. Clinical features do not differ between depressions with or without prior stressful life events. Certain genetic variations in the serotonin receptor system seem to increase the risk of developing depression in relation to experiencing stressful life......The aim of the present review was to present clinical aspects of recent research in genes, the experience of stressful life events and depression. 60-70% experience a moderate to severe stressful life event half a year prior to the first onset of depression, whereas later depressive episodes...

  7. Psykosociale interventioner ved debuterende psykoser i skizofrenispektret

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Bertelsen, Mette

    2008-01-01

    The possibilities for intervention in the early phases of schizophrenia and schizophrenia-like psychosis were reviewed. Long duration of untreated psychosis is related to persistent psychotic symptoms. Early detection programmes can reduce the duration of untreated psychosis and thereby probably...... improve outcome. There is ample evidence that intensive specialised assertive intervention during the early phase of psychotic symptoms is effective in improving several outcomes. Family intervention reduces risk of remission and improve compliance with antipsychotic medication....

  8. Osmotisk demyeliniseringssyndrom ved Addisonkrise og svaer hyponatriaemi

    DEFF Research Database (Denmark)

    Andersen, Signe Elisabeth Bødker; Stausbøl-Grøn, Brian; Rasmussen, Torsten Bloch

    2008-01-01

    describe a case with extremely low plasma sodium and subsequent development of ODS. Correction which is too slow may lead to cerebral oedema, brain stem herniation and low sodium encephalopathy. Correction which is too fast may cause ODS. The dilemma is accentuated by concomitant Addison crisis...

  9. "Jeg har altid haft nemt ved tingene"

    DEFF Research Database (Denmark)

    Rasmussen, Annette; Rasmussen, Palle

    Rapporten analyserer talentundervisningen på 8. og 9. klassetrin i Hjørring Kommune i skoleåret 2006-2007. Der var tale om ekstraundervisning uden for normal skoletid. Det faglige indhold lå inden for fysik, kemi, biologi, matematik og engelsk, og både folkeskolelærere og gymnasielærere medvirkede...

  10. Helbredsrisici ved eksponering for styren i glasfiberplastindustrien

    DEFF Research Database (Denmark)

    Kolstad, Henrik Albert; Ebbehøj, Nielse; Bonde, Jens Peter

    2012-01-01

    This is a summary of the health risks of occupational styrene exposure based on recent reviews. We conclude about the exposure levels that there is strong evidence that styrene causes acute irritation of eyes and respiratory tract above 25 ppm, genotoxic effects above 10 ppm, and persistent nervous...... or relevant exposure levels. We recommend reconsideration of the current Danish threshold limit value of 25 ppm, biological monitoring of styrene exposed workers, and epidemiological analyses of styrene exposure levels and long-term health effects among employees of the Danish reinforced plastics industry....... system effects with for instance reduced psychological performance, colour discrimination and hearing level following long-term styrene exposure above 10 ppm. There is moderate evidence of a causal association with cancer, but data are not sufficient to allow us to pinpoint specific cancers at risk...

  11. Oxidativt stress og genetiske polymorfismer ved KOL

    DEFF Research Database (Denmark)

    Dalsgarô, Oli Jacob; Vestbo, Jørgen

    2002-01-01

    is tobacco smoking. In recent years there has been increasing focus on the pathophysiological events leading to COPD, and oxidative stress has been suggested as one of the major pathophysiological factors. Clinical studies indicate a causal association between tobacco smoking, oxidative stress, increased...... inflammatory response, and destruction of lung parenchyma. This article reviews the clinical literature on oxidative stress as a pre-inflammatory state, leading to COPD in susceptible smokers....

  12. Psykosociale interventioner ved debuterende psykoser i skizofrenispektret

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Bertelsen, Mette

    2008-01-01

    improve outcome. There is ample evidence that intensive specialised assertive intervention during the early phase of psychotic symptoms is effective in improving several outcomes. Family intervention reduces risk of remission and improve compliance with antipsychotic medication....

  13. Akut kirurgisk behandling ved malignt cerebralt infarkt

    DEFF Research Database (Denmark)

    Lilja-Cyron, Alexander; Eskesen, Vagn; Hansen, Klaus

    2016-01-01

    Malignant stroke is an intracranial herniation syndrome caused by cerebral oedema after a large hemispheric or cerebellar stroke. Malignant middle cerebral artery infarction is a devastating disease with a mortality around 80% despite intensive medical treatment. Decompressive craniectomy reduces...... mortality and improves functional outcome - especially in younger patients (age ≤ 60 years). Decompression of the posterior fossa is a life-saving procedure in patients with malignant cerebellar infarctions and often leads to good neurological outcome....

  14. Kromosomforandringer ved medfødt hjertemisdannelse

    DEFF Research Database (Denmark)

    Larsen, Lars Allan

    2011-01-01

    Congenital heart disease (CHD) affects 1% of the population. The aetiology of CHD is complex and largely unknown, comprising both environmental and genetic components. Recent progress in molecular cytogenetics has led to the identification of rare genomic copy number variants (CNVs......) in a significant proportion of CHD patients. These novel results imply new diagnostic possibilities and may aid in the identification of novel disease genes....

  15. Demokratiske udfordringer ved fondenes stigende indflydelse

    DEFF Research Database (Denmark)

    Boje, Thomas P.

    2016-01-01

    Private fondes bidrag til civilsamfundet udgør 12 milliarder omkring 7 procent af den samlede indtægt og har været stigende gennem de sidste år. Fondenes indflydelse er dog langt større i og med, at de for strategiske satsninger i civilsamfundet. derfor vigtigt med større åbenhed og gennemstigtighed......Private fondes bidrag til civilsamfundet udgør 12 milliarder omkring 7 procent af den samlede indtægt og har været stigende gennem de sidste år. Fondenes indflydelse er dog langt større i og med, at de for strategiske satsninger i civilsamfundet. derfor vigtigt med større åbenhed og...

  16. Fortsat indikation for jodid-123 ved thyroideaskintigrafi

    DEFF Research Database (Denmark)

    Andersen, Kim Francis; Hendel, Helle Westergren

    2011-01-01

    . Application of iodine-123 can show diagnostic superiority owing to ideal tracer properties for scintigraphic imaging of the thyroid gland, such as pure gamma emission, organic binding and slow wash-out. The cons are a high radiation burden, price and lack of availability, as iodine-123 is a cyclotron product....

  17. Tidsforbrug ved monitorering af postoperativ oxygenstatus

    DEFF Research Database (Denmark)

    Lavrsen, M J; Tuxøe, J I; Koch, J S

    1997-01-01

    oximetry was 100% but only 89% for arterial blood gas measurement, because the laboratory did not analyse samples where the ice surrounding the syringe had melted when arriving at the laboratory or if there were air bubbles in the blood sample. At Hvidovre Hospital the results from the blood gas analysis......The purpose of the study was to compare use of time with pulse oximetry versus arterial blood gas measurement on the general surgical ward. Eighty patients who had just had major orthopaedic or abdominal surgery were included in the study at two hospitals in Copenhagen. Success rate for pulse...... requiring treatment. With pulse oximetry reliable monitoring of arterial oxygenation can be obtained non-invasively and with a high success rate. Furthermore, the results are available for the clinician immediately compared with arterial blood gas measurement, where there is a delay in getting the results...

  18. Rickettsiose som differentialdiagnostisk overvejelse ved rejserelateret feber

    DEFF Research Database (Denmark)

    Kibsgaard, Line

    2012-01-01

    , rickettsiosis should be considered in the returned traveller with fever, especially when malaria, dengue fever and typhoid fever have been excluded. There is a possibility that doxycycline may have a prophylactic effect on rickettsiosis, but this thesis is only imaginary and needs further investigation....

  19. Hastigt progredierende synstab ved idiopatisk intrakraniel hypertension

    DEFF Research Database (Denmark)

    Skau, Maren; Jensen, Rigmor; Milea, Dan

    2009-01-01

    Idiopathic intracranial hypertension (IIH) is a condition of increased intracranial pressure of unknown aetiology. Slowly progressing visual defects secondary to papilloedema are well-known complications. Rapidly progressing visual loss is rare. A case of acute and rapidly progressing visual loss...

  20. Rapport om digitale oplysninger ved Aalborg Universitet

    DEFF Research Database (Denmark)

    Bønsing, Sten

    Rapport til Aalborg Universitets ledelse vedr. brug af digitale oplysninger i forbindelse med e-mailing, databaser, hjemmesider mv.......Rapport til Aalborg Universitets ledelse vedr. brug af digitale oplysninger i forbindelse med e-mailing, databaser, hjemmesider mv....

  1. Utfordringer ved prima vista tolking i asylintervjuer

    Directory of Open Access Journals (Sweden)

    Tatjana Radanović Felberg

    2015-01-01

    Full Text Available Every year the Norwegian Directorate of Immigration (UDI conducts approximately 10,000 interpreter-mediated asylum interviews in Norway. Each asylum interview ends with the interpreter providing a sight translation of the draft interview report (an oral translation of the text to the asylum seeker. The UDI wished to find out why some interpreters took so much more time than others for sight translation. In response, Oslo and Akershus University College of Applied Sciences initiated a pilot project. The project’s working hypothesis was that slow sight translation was due mainly to a combination of three factors: interpreters’ poor reading skills; interpreters’ poor interpreting techniques; and/or interpreters’ unfamiliarity with the appropriate genre/style. A more complex picture emerged, however, from an analysis of 13 asylum interviews; group work involving 108 UDI interpreters; and discussions with UDI specialists. An asylum report is the joint product of all the participants in an asylum interview, who are typically the asylum seeker, the interviewer and the interpreter. The pilot study showed that each participant could contribute in various ways to slowing the speed of sight translation. Contributing factors identified that were unrelated to the interpreter included the interviewer’s competence in interview techniques; the interviewer’s competence in creating a written record of speech; the asylum seeker’s narrative ability; and the asylum seeker’s ability to correct mistakes in the draft report. All these factors may have just as much impact on the speed of sight translation as the interpreter’s competence. In addition, the physical strain caused by the length of asylum interviews (six hours plus and the emotional stress potentially caused by such institutional interviews may affect the communicative abilities of all participants. As sight translation in the public sector is an under-researched area, the article starts with a discussion of terminology and an explanation of the UDI context. It then presents a possible explanation for slowness of sight translation and concludes that there is a need for more research into the various factors relevant to sight translation in the public sector and that there is a need to provide systematic training for both interpreters and interpreter users.

  2. Beta-2-mikroglobulin ved medicinske sygdomme

    DEFF Research Database (Denmark)

    Hansen, P B; Olsen, Niels Vidiendal

    1989-01-01

    Beta-2-microglobulin (beta 2M) is a low-molecular protein which is filtered freely over the glomeruli. Under normal circumstances, more than 99.9% is resorbed in the proximal tubuli of the kidneys and is metabolized there. In renal disease with damage to this segment of the nephron, eg acute tubulo...

  3. Molekylaer patogenese ved monogen og polygen fedme

    DEFF Research Database (Denmark)

    Larsen, Philip J; Echwald, Søren Morgenthaler; Sørensen, Thorkild I A

    2006-01-01

    During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us c...... closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns....

  4. Oxidativt stress og genetiske polymorfismer ved KOL

    DEFF Research Database (Denmark)

    Dalsgarô, Oli Jacob; Vestbo, Jørgen

    2002-01-01

    Chronic obstructive pulmonary disease (COPD) is characterised by progressive diminution of pulmonary function with minimal reversibility. The initially organ-related symptoms gradually involve secondary organs and end-stage COPD can be considered a systemic disease. The most important cause of CO...... inflammatory response, and destruction of lung parenchyma. This article reviews the clinical literature on oxidative stress as a pre-inflammatory state, leading to COPD in susceptible smokers.......Chronic obstructive pulmonary disease (COPD) is characterised by progressive diminution of pulmonary function with minimal reversibility. The initially organ-related symptoms gradually involve secondary organs and end-stage COPD can be considered a systemic disease. The most important cause of COPD...... is tobacco smoking. In recent years there has been increasing focus on the pathophysiological events leading to COPD, and oxidative stress has been suggested as one of the major pathophysiological factors. Clinical studies indicate a causal association between tobacco smoking, oxidative stress, increased...

  5. Erfaringer med lyd ved e-undervisning

    DEFF Research Database (Denmark)

    Møller, Eval Rud

    2009-01-01

    opnås. I forbindelse med synkron vejledning med lyd er det således især vigtigt at internetforbindelsen har en tilstrækkelig høj upload og download hastighed. I forbindelse med elektronisk undervisningsmateriale kan adskillige faktorer forårsage forringet lydkvalitet og det er derfor vigtigt at lyden...

  6. Avancering af maksillen ved brug af osseodistraktion

    DEFF Research Database (Denmark)

    Andersen, Kristian; Svenstrup, M; Nørholt, Sven Erik

    2010-01-01

    . Gennemgangen omfatter emnerne: 1) stabilitet og recidiv, 2) peroperativ og postoperativ morbiditet samt gener, 3) ændringer af blødtvæv under distraktion, 4) ændringer af velopharynx og taleevne samt 5) psykosociale effekter af behandlingen. Resultater – De eksisterende artikler har samlet set generelle...

  7. Kognitive forstyrrelser ved svaer traumatisk hjerneskade

    DEFF Research Database (Denmark)

    Engelmann, Christina Malling; Siert, Lars

    2007-01-01

    Traumatic brain injury (TBI) very often has extensive effects of cognitive character such as changes in recognition, thought, memory, language and perception. The purpose of this paper is to give a short status of cognitive impairment after severe traumatic brain injury and to illustrate...... that cognitive impairment varies according to levels of consciousness. The article shortly describes typical observed behaviour in the patient when waking up after severe TBI, including post-traumatic amnesia. Udgivelsesdato: 2007-Jan-15...

  8. Biologisk terapi ved juvenil idiopatisk artritis

    DEFF Research Database (Denmark)

    Herlin, Troels

    2008-01-01

    In recent years the treatment of juvenile idiopathic arthritis (JIA) has undergone marked changes. There is substantial evidence that inhibitors of tumor necrosis factor alpha (TNFalpha) like etanercept, infliximab and adalimumab show significant efficacy when standard therapy fails, and long-ter...

  9. Smerte og smertemestring ved juvenil idiopatisk artritis

    DEFF Research Database (Denmark)

    Herlin, Troels; Thastum, Mikael

    2008-01-01

    Pain is one of the primary symptoms of juvenile idiopathic arthritis (JIA). JIA patients have reduced pain tolerance and pain threshold compared to healthy controls. In children with JIA the greater use of coping strategies such as problem-solving, positive self-statements and distraction consist...

  10. Analyse af vindklima ved Navitas Park

    DEFF Research Database (Denmark)

    Rasmussen, Michael R.; Lauridsen, Thomas Bank

    Formålet med denne vindklimaanalyse er at afklare, hvorvidt opførelsen af Navitas Park på Århus Havn vil medføre uhensigtsmæssige eller farlige vindforhold for fodgængere i området omkring bygningen.......Formålet med denne vindklimaanalyse er at afklare, hvorvidt opførelsen af Navitas Park på Århus Havn vil medføre uhensigtsmæssige eller farlige vindforhold for fodgængere i området omkring bygningen....

  11. Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    DEFF Research Database (Denmark)

    Fisker, Jacob; Buchwald, Christian von; Johansen, Helle Krogh

    2011-01-01

    Microbial biofilms are known to cause persistent foreign-body infections and have recently been acknowledged as involved in more than 65% of all human infections. Microbial biofilms have been detected in chronic rhinosinusitis, and chronic rhinosinusitis is mandatory in patients with cystic...

  12. Beskeden risiko for fosfatnefropati ved colonudrensning

    DEFF Research Database (Denmark)

    Schmidt, Palle Nordblad; Hendel, Jakob W

    2010-01-01

    Acute phosphate nephropathy is a rare, but serious adverse event associated with the use of sodium phosphate for bowel cleansing. It may lead to permanent renal impairment and a need for dialysis. The aetiology is hyperphosphataemia caused by intestinal absorption of the cleanser. Risk factors in...... include: advanced age, existing kidney disease, decreased intravascular volume, and medications affecting renal perfusion or function such as diuretics, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and possibly nonsteroidal anti-inflammatory drugs....

  13. Antibiotikavalg ved purulent meningitis uden bakteriologisk diagnose

    DEFF Research Database (Denmark)

    Krarup, H B

    1989-01-01

    A case of meningitis in a 16 month old boy caused by Hemophilus influenzae resistant to ampicillin is presented. The question is raised whether a third generation cephalosporin such as cefotaxime should be the drug of choice in the treatment of bacterial meningitis with unknown etiology...

  14. Regulering af cytokindannelse ved inflammatoriske tarmsygdomme

    DEFF Research Database (Denmark)

    Ferrero-Miliani, Laura; Seidelin, Jakob Benecidt; Nielsen, Ole Haagen

    2006-01-01

    Interleukin-1beta (IL-1beta) is a pivotal mediator in the inflammatory immune response that is characteristic of a number of chronic disorders. The etiology and pathophysiology of inflammatory bowel disease (IBD) have for many years been an enigma. The recent identification of the inflammasome...

  15. SNG-log i boring ved Tinglev

    DEFF Research Database (Denmark)

    Korsbech, Uffe C C; Madsen, Peter Buch

    1999-01-01

    A 4-windows SNG-log has been run in a 185 m exploration borehole at Tinglev. A new method for examining the effect of borehole geometry on the measured gamma-spectra has been tested.......A 4-windows SNG-log has been run in a 185 m exploration borehole at Tinglev. A new method for examining the effect of borehole geometry on the measured gamma-spectra has been tested....

  16. Stressfaktoren ved rumlig fleksibilitet i arbejdslivet

    OpenAIRE

    Hansen, Rebecca Stormly

    2016-01-01

    This thesis is written to explore the causes of stress regarding spatial flexibility. The thesis revolves around the question; which circumstances of spatial flexibility can cause an employee to work more than his or her psyche can handle. When the possibility of spatial flexibility is introduced to a workplace, one must assume that it is intended to benefit the given institution, the management and the employees. No one benefits from an employee who feels overloaded; so why is this occasiona...

  17. Iatrogene duralaesioner ved dekompressionskirurgi i lumbalcolumna

    DEFF Research Database (Denmark)

    Thomsen, Frederik; Amtoft, Ole; Andersen, Mikkel

    2010-01-01

    INTRODUCTION: Iatrogenic dural tear with cerebrospinal fluid leakage is a known complication of lumbar surgery of the columna. In the literature, the incidence is 3-16%. MATERIAL AND METHODS: The study was a retrospective, consecutive review of electronic patient records after spinal surgery...

  18. Epidemiologi ved juvenil systemisk lupus erythematosus

    Directory of Open Access Journals (Sweden)

    Odd Vinje

    2009-10-01

    Full Text Available We have previously described the impact of Apgar scores on later major and minor disabilities. According to these and other studies, children with low Apgar scores have to show symptoms of neonatal encephalopathy in the first week of life to be at risk of developing later disabilities. Information on neonatal encephalopathy has traditionally been less accessible than Apgar scores in The Medical Birth Registry of Norway (MBRN. In the present study the possibility of extracting information on neonatal encephalopathy from the new notification form to the MBRN, which was introduced in late 1998, was investigated. The introduction of specific and generally accepted definitions of neonatal diagnoses combined with more comprehensive reports to MBRN from the neonatal departments may render registry based studies on neonatal encephalopathy possible in the future

  19. Arbejdsmiljø ved udbud af busdrift

    DEFF Research Database (Denmark)

    Wiegmann, Inger-Marie; Mathiesen, Karin; Hasle, Peter

    En undersøgelse af sammenhængen mellem arbejdsmiljø og udbud af busdrift i tre trafikselskabet. Resultaterne peger på at arbejdsmiljøet går fra udelukkende til at være et anliggende mellem arbejdsgiver og arbejdstager til et trepartsforhold hvor også udbyder (trafikselskabet) får et ansvar og har...

  20. Billeddiagnostiske aspekter ved damage control-kirurgi

    DEFF Research Database (Denmark)

    Ewertsen, Caroline; Hansen, Kristoffer Lindskov; Nielsen, Michael Bachmann

    2011-01-01

    The imaging modalities computed tomography (CT) and the ultrasonography (US) examination focused assessment with sonography for trauma (FAST) in relation to damage control in traumas are discussed. CT has the advantage of high sensitivity and specificity for detection of organ specific lesions....... FAST ultrasound is a good screening tool for intraperitoneal bleeding, but the sensitivity and specificity is lower than by CT. We recommend FAST-US prehospitally or early in the trauma room resuscitation. Haemodynamically stable patients with relevant traumas should undergo CT....

  1. Okulære symptomer ved syfilis

    DEFF Research Database (Denmark)

    Kromann Opstrup Abildgaard, Søren; Javadi-Ottosen, Søren; Baggesen, Kirsten Lau

    2014-01-01

    pallidum. This case illustrates that symptoms of the syphilis disease can come from different organ systems and cross medical specialties. We encourage clinicians to more readily think of syphilis whenever there is a sexual active patient with complaints from different parts of the body....

  2. Det komplekse kliniske billede ved arvelige mitokondriesygdomme

    DEFF Research Database (Denmark)

    Frederiksen, Anja Lisbeth; Nielsen, Morten Frost; Yderstræde, Knud

    2014-01-01

    Mitochondria produce cellular energy, which is of vital importance for cellular metabolism. The organelles contain their own genetic material (i.e. mitochondrial DNA (mtDNA)) with a matrilineal inheritance. Mutations in the mtDNA may cause mitochondrial disease affecting multiple organs leading...... to diabetes, hearing impairment, muscle fatigue, ptosis and stroke-like episodes in varying combinations and severity. The variable phenotypic presentations make it a challenge to recognize mitochondrial diseases and, consequently, the correct diagnosis is often delayed....

  3. Billeddiagnostik ved levermetastaser fra kolorektal cancer

    DEFF Research Database (Denmark)

    Mollerup, Talie Khadem; Lorentzen, Torben; Møller, Jakob M

    2015-01-01

    Hepatic metastases (HM) are amongst the most important prognostic factors in patient survival from colorectal cancer. The diagnostic imaging techniques for accurate detection and characterization of colorectal metastases are therefore vital. In a review of the literature, MRI showed the highest...... sensitivity for detection of HM lesions ionizing...... radiation....

  4. Risiko for affektiv lidelse ved multipel sklerose

    DEFF Research Database (Denmark)

    Stenager, Elsebeth Nylev; Stage, Kurt Bjerregaard; Stenager, Egon

    2011-01-01

    An increased risk for depression has been found in multiple sclerosis (MS). The purpose of the present study has been to give suggestions to guidelines for diagnosis and treatment of depression in MS in Denmark based on the international literature and recommendations. The method was a review...

  5. Diagnosticering af choledochussten ved symptomgivende galdestenssygdom

    DEFF Research Database (Denmark)

    Kristiansen, V B; Rosenberg, J; Kehlet, H

    2000-01-01

    one or more blood tests for liver function are elevated and/or the diameter of the common bile duct is > or = 10 mm on transabdominal ultrasound. Magnetic resonance cholangiography, endoscopic ultrasound, laparoscopic ultrasound, intraoperative cholangiography and endoscopic retrograde cholangiography...... as such in the future. Patients with cholangitis, jaundice and common bile duct stones visualised by transabdominal ultrasound have a high risk of common bile duct stones, and these patients can therefore undergo endoscopic retrograde cholangiography directly. Other patients should have a magnetic resonance...

  6. Besøgscenter ved fregatten Jylland

    DEFF Research Database (Denmark)

    Lund, Nils-Ole

    2005-01-01

    Det maritime besøgscenter består af riggerværksted, et værfts- og bådbyggeri og en værkstedsbygning til smed, tømrer, snedker og maler - mens museumsafsnittet består af udstilling, auditorium, cafe og administration i en lang bygning, der markerer indgangen til udstillingsområdet.......Det maritime besøgscenter består af riggerværksted, et værfts- og bådbyggeri og en værkstedsbygning til smed, tømrer, snedker og maler - mens museumsafsnittet består af udstilling, auditorium, cafe og administration i en lang bygning, der markerer indgangen til udstillingsområdet....

  7. Sygdomsmekanismer og terapeutiske perspektiver ved neurofibromatose 1

    DEFF Research Database (Denmark)

    Kjærulff, Ole; Wandall, Hans

    2012-01-01

    Neurofibromatosis 1 (NF1, von Recklinghausen's disease) is a dominantly inherited multi-organ disease defined primarily by café au lait patches and neurofibromas. NF1 predisposes to cancer and is associated with cognitive dysfunction and learning defects. In recent years, considerable progress has...

  8. Definition, klassifikation og epidemiologi ved whiplash

    DEFF Research Database (Denmark)

    Jensen, Troels Staehelin; Kasch, Helge; Bach, Flemming Winther

    2010-01-01

    A whiplash trauma is caused by an acceleration-deceleration force transferring its energy to the cervical spine. Whiplash-associated disorder (WAD) refers to the symptoms that develop after a whiplash injury. The prognosis is favorable with recovery in over 90% of the injured subjects...

  9. Assisteret reproduktion ved HIV-infektion

    DEFF Research Database (Denmark)

    Kazlauskaite, Ramune; Østergaard, Lars; Laursen, Tinne

    2009-01-01

    INTRODUCTION: In Denmark assisted reproductive treatment to HIV discordant couples is offered in order to minimize risk of horizontal transmission of virus. MATERIAL AND METHODS: The outcome of 24 HIV-seropositive couples referred with a wish for parenthood to Aarhus University Hospital, Skejby...... horizontal nor vertical infection occurred. CONCLUSION: Our study confirms that insemination is a good first-choice treatment in respect to chance of pregnancy and risk for virus transmission in HIV-seropositive couples in cases without indication for IVF. Udgivelsesdato: 2009-Apr-27...

  10. Laparoskopisk subtotal kolecystektomi ved kompliceret galdestenssygdom

    DEFF Research Database (Denmark)

    Semenisina, Galina; Rosenberg, Jacob; Gögenur, Ismail

    2010-01-01

    In laparoscopic cholecystectomy conversion to open surgery occurs. Patients who would otherwise need conversion can benefit from laparoscopic subtotal cholecystectomy (LSC). We present a review of studies in which outcome after LSC has been investigated. The results show reduced conversion rates,......, shorter hospital stay, minimal complications and mortality rates. Acute cholecystitis, cirrhosis, Mirrizi syndrome type I are the indications for LSC. Randomized prospective trials are needed to investigate safety and long-term effects....

  11. Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    DEFF Research Database (Denmark)

    Fisker, Jacob; Buchwald, Christian von; Johansen, Helle Krogh

    2011-01-01

    Microbial biofilms are known to cause persistent foreign-body infections and have recently been acknowledged as involved in more than 65% of all human infections. Microbial biofilms have been detected in chronic rhinosinusitis, and chronic rhinosinusitis is mandatory in patients with cystic fibro...... fibrosis. We believe that a reservoir for a sustained lung infection in these patients might be found in the nasal sinuses, and that the sinuses may act as a reservoir for reinfection after CF-patient lung transplants. Further studies are necessary....

  12. Kontrol af serumcalcium med cinacalcet ved parathyroideacancer

    DEFF Research Database (Denmark)

    Sanden, Anne Katrine; Vestergaard, Peter

    2009-01-01

    Treatment with cinacalcet and intravenous bisphosphonate has improved the previously often fatal prognosis of parathyroid cancer. We report two cases, of which one did not react to treatment and died within a short time-frame. In the other case, cinacalcet controlled serum calcium during...

  13. Ekstrapulmonale komplikationer ved mycoplasma pneumoniae-infektioner

    DEFF Research Database (Denmark)

    Bjørn, Anne-Mette Bay; Lebech, Anne-Mette K

    2002-01-01

    Mycoplasma pneumoniae is a common cause of atypical pneumonia in children and young adults. The infection is generally mild and only a very few patients are admitted to hospital. However, extrapulmonary complications are well recognised--mostly as manifestations from the central nervous system (C...

  14. Usikker diagnostik med ultralydskanning ved fejlplaceret spiral

    DEFF Research Database (Denmark)

    Egekvist, Anne Gisselmann; Høj, Lars; Riiskjaer, Mads

    2014-01-01

    Ultrasound scan did not locate misplaced intrauterine devices One of the rare but serious complications of intrauterine contraception is perforation of the uterine wall at insertion. We present two cases where intrauterine devices went missing. In both cases abdominal and vaginal ultrasound scan...

  15. Det komplekse kliniske billede ved arvelige mitokondriesygdomme

    DEFF Research Database (Denmark)

    Frederiksen, Anja Lisbeth; Nielsen, Morten Frost; Yderstræde, Knud

    2014-01-01

    Mitochondria produce cellular energy, which is of vital importance for cellular metabolism. The organelles contain their own genetic material (i.e. mitochondrial DNA (mtDNA)) with a matrilineal inheritance. Mutations in the mtDNA may cause mitochondrial disease affecting multiple organs leading t...... to diabetes, hearing impairment, muscle fatigue, ptosis and stroke-like episodes in varying combinations and severity. The variable phenotypic presentations make it a challenge to recognize mitochondrial diseases and, consequently, the correct diagnosis is often delayed.......Mitochondria produce cellular energy, which is of vital importance for cellular metabolism. The organelles contain their own genetic material (i.e. mitochondrial DNA (mtDNA)) with a matrilineal inheritance. Mutations in the mtDNA may cause mitochondrial disease affecting multiple organs leading...

  16. Osteoporose er hyppig ved Parkinsons sygdom

    DEFF Research Database (Denmark)

    Ezzatian-Ahar, Shabnam; Schwarz, Peter; Pedersen, Stephen Wørlich

    2015-01-01

    The risk of developing osteoporosis, as well as Parkinson's disease (PD) is increased with increasing age, resulting in increased risk of fracture, particularly hip fractures. Each one of these two conditions can be debilitating and affect the individual patient's quality of life negatively. PD...

  17. Finnålsaspirationscytologi ved mammografiscreening

    DEFF Research Database (Denmark)

    Engvad, Birte; Laenkholm, Anne-Vibeke; Schwartz, Walter

    2009-01-01

    INTRODUCTION: In the year 2000 a quality assurance programme for the preoperative breast diagnostics was introduced in Denmark. The programme was based on the "European guidelines for quality assurance in breast cancer screening and diagnosis" where - among other measures - five cytological...... diagnostic classes were introduced. The aim of this study was to evaluate the quality assurance programme in a screening population to determine whether fine needle aspiration cytology (FNAC) as first choice remains a useful tool in the preoperative diagnostics, or if needle core biopsy should be the first...... of 66% of the 783 FNACs had a malignant cytology diagnosis, which in 99% of the cases turned out to be the correct diagnosis. Four lesions were false positives all of which represented benign proliferative breast diseases. The surgical procedures in these cases were either excisional biopsy...

  18. Intensiv versus standardbehandling ved debuterende psykose

    DEFF Research Database (Denmark)

    Bertelsen, Mette; Jeppesen, Pia; Petersen, Lone

    2009-01-01

    A total of 547 patients with a first episode of psychosis were randomised to two years of intensive early intervention programme (OPUS) versus standard treatment. OPUS treatment consisted of Assertive Community Treatment (ACT) with manuals for family involvement and social skills training. Standard...

  19. Bæredygtige systemleverancer ved renovering

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2014-01-01

    bliver opfattet som ”bæredygtigt byggeri”. Bæredygtighed i byggeri rummer dog meget mere og især ressourceproblematikken omkring materialer, deres indvinding, anvendelse og genbrug bliver til vigtige spørgsmål i fremtiden, ikke kun med blik på miljøet, men også med blik på etiske, sociale og ikke til...... disse kan få , alt efter hvilken del af byggebranchen er berørt. Standarder og certifikater for bærdygtigt byggeri bliver derfor, overordnet set, modtaget positiv i branchen og kan midlertidig skabe større efterspørgsel for bæredygtige bygninger. Set udefra medfører certifikater dog også faren...... for greenwashing, især når disse certifikater uddeles af private foreninger eller firmaer. Standarder og certifikater tilgodeser dog sjældent at bygninger, over deres performative kvaliteter, også har en kulturbærende funktion, som selvfølgelig er en bæredygtighedsaspekt. Bygningernes arkitektur er yderst vigtigt...

  20. Psykosociale interventioner ved debuterende psykoser i skizofrenispektret

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Bertelsen, Mette

    2008-01-01

    The possibilities for intervention in the early phases of schizophrenia and schizophrenia-like psychosis were reviewed. Long duration of untreated psychosis is related to persistent psychotic symptoms. Early detection programmes can reduce the duration of untreated psychosis and thereby probably...

  1. Akut kirurgisk behandling ved malignt cerebralt infarkt

    DEFF Research Database (Denmark)

    Lilja-cyron, Alexander; Eskesen, Vagn; Hansen, Klaus

    2016-01-01

    Malignant stroke is an intracranial herniation syndrome caused by cerebral oedema after a large hemispheric or cerebellar stroke. Malignant middle cerebral artery infarction is a devastating disease with a mortality around 80% despite intensive medical treatment. Decompressive craniectomy reduces...

  2. Energirigtig ventilation ved renovering og byfornyelse

    DEFF Research Database (Denmark)

    Klint, Jakob; Bergsøe, Niels Christian; Pedersen, Peder Vejsig

    endnu ikke foreligger veldokumenterede målinger og data, men som vurderes at have store potentialer i forhold til renovering af ældre ejendomme. Den primære målgruppe for denne publikation er de, der beskæftiger sig med administration og forvaltning af etageboliger, og har interesse i gode og...

  3. Molekylaer patogenese ved monogen og polygen fedme

    DEFF Research Database (Denmark)

    Larsen, Philip J; Echwald, Søren Morgenthaler; Sørensen, Thorkild I A

    2006-01-01

    During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us...

  4. Oxidativt stress og genetiske polymorfismer ved KOL

    DEFF Research Database (Denmark)

    Dalsgarô, Oli Jacob; Vestbo, Jørgen

    2002-01-01

    Chronic obstructive pulmonary disease (COPD) is characterised by progressive diminution of pulmonary function with minimal reversibility. The initially organ-related symptoms gradually involve secondary organs and end-stage COPD can be considered a systemic disease. The most important cause of COPD...... is tobacco smoking. In recent years there has been increasing focus on the pathophysiological events leading to COPD, and oxidative stress has been suggested as one of the major pathophysiological factors. Clinical studies indicate a causal association between tobacco smoking, oxidative stress, increased...... inflammatory response, and destruction of lung parenchyma. This article reviews the clinical literature on oxidative stress as a pre-inflammatory state, leading to COPD in susceptible smokers....

  5. Forskning ved regionale hospitalsenheder i Vestdanmark

    DEFF Research Database (Denmark)

    Nielsen, Gunnar Lauge; Petersen, Lars Jelstrup; Hornung, Nete

    2009-01-01

    only equivalent to 0.1%, 0.3%, 0.3% and 0.6% of the total budget. Most hospitals had associate professors, but only five had full professors. Seven hospitals supplied laboratories and technical facilities, eight hospitals held staff-meetings on a regular basis and four published an annual report......INTRODUCTION: According to recently passed Danish legislation, all Danish hospitals are obliged to take part in scientific research. As data on financial support for research activities are lacking, we assessed the resources allocated to research from the budget of the central hospital management...... on research activities. CONCLUSION: In the majority of regional hospitals in Western Denmark, less than 0.3% of the total budget administered by the central hospital management was allocated specifically for research. These figures, however, may not be accurate as individual departments may allocate...

  6. Helbredsrisici ved eksponering for styren i glasfiberplastindustrien

    DEFF Research Database (Denmark)

    Kolstad, Henrik Albert; Ebbehøj, Nielse; Bonde, Jens Peter

    2012-01-01

    or relevant exposure levels. We recommend reconsideration of the current Danish threshold limit value of 25 ppm, biological monitoring of styrene exposed workers, and epidemiological analyses of styrene exposure levels and long-term health effects among employees of the Danish reinforced plastics industry.......This is a summary of the health risks of occupational styrene exposure based on recent reviews. We conclude about the exposure levels that there is strong evidence that styrene causes acute irritation of eyes and respiratory tract above 25 ppm, genotoxic effects above 10 ppm, and persistent nervous...... system effects with for instance reduced psychological performance, colour discrimination and hearing level following long-term styrene exposure above 10 ppm. There is moderate evidence of a causal association with cancer, but data are not sufficient to allow us to pinpoint specific cancers at risk...

  7. Definition, klassifikation og epidemiologi ved whiplash

    DEFF Research Database (Denmark)

    Jensen, Troels Staehelin; Kasch, Helge; Bach, Flemming Winther

    2010-01-01

    A whiplash trauma is caused by an acceleration-deceleration force transferring its energy to the cervical spine. Whiplash-associated disorder (WAD) refers to the symptoms that develop after a whiplash injury. The prognosis is favorable with recovery in over 90% of the injured subjects. In a fract...

  8. Udfordringer og strategier ved produktion af biodiesel

    DEFF Research Database (Denmark)

    Madsen, Anders Theilgaard; Riisager, Anders; Fehrmann, Rasmus

    2009-01-01

    I takt med at verdens olieressourcer forbruges, øges fokus på fornybare brændsler, der ikke medfører stigning i CO2-udledningen. Der er især opmærksomhed på biobrændstoffer som mulige alternativer eller additiver til petrobrændstof...

  9. Nye farmakologiske behandlingsmodaliteter ved type 2-diabetes

    DEFF Research Database (Denmark)

    Madsbad, Sten; Hermansen, Kjeld

    2012-01-01

    The variable pathogenesis and progressive nature of type 2 diabetes emphasise the need for new antidiabetic treatments. The long acting glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors have improved the treatment. Novel approaches include inhibitors of sodium glucose...... co-transporter 2, which increase renal glucose elimination, G-protein-coupled receptor agonists, which potentiate insulin and incretin hormone secretion. Proof of principle has been shown for glucagon receptor agonists, glucokinase activators and treatment with dual intestinal peptides, which all...

  10. Oxidativt stress og genetiske polymorfismer ved KOL

    DEFF Research Database (Denmark)

    Dalsgarô, Oli Jacob; Vestbo, Jørgen

    2002-01-01

    Chronic obstructive pulmonary disease (COPD) is characterised by progressive diminution of pulmonary function with minimal reversibility. The initially organ-related symptoms gradually involve secondary organs and end-stage COPD can be considered a systemic disease. The most important cause of COPD...... is tobacco smoking. In recent years there has been increasing focus on the pathophysiological events leading to COPD, and oxidative stress has been suggested as one of the major pathophysiological factors. Clinical studies indicate a causal association between tobacco smoking, oxidative stress, increased...

  11. Generaliserede kramper som debutsymptom ved Gitelmans syndrom

    DEFF Research Database (Denmark)

    Hvelplund, Carolina; Jeppesen, Eva Mosfeldt; Mortensen, Henrik B

    2009-01-01

    Gitelman's syndrome is a rare autosomal recessive syndrome presenting with hypocalciuria, hypomagnesiemia and hypokalemic metabolic alkalosis. This case reports a patient admitted with generalized seizures with the above-mentioned biochemical abnormalities, thus representing a rare onset...... of Gitelman's syndrome which - to our knowledge - has not been described previously. The patient had a homozygote deletion of the CLC-KB gene, CLCNKB. The case was successfully treated by correcting hypokalemia and hypomagnesiemia with supplemental potassium and magnesium. Udgivelsesdato: 2009-Mar-2...

  12. Neuroradiologiske forandringer ved undertrykkelse af tics

    DEFF Research Database (Denmark)

    Larsen, Sara Bohn; Sørensen, Camilla Birgitte; Skov, Liselotte

    2017-01-01

    Neuroradiological changes by suppression of tics Tourette’s syndrome is characterized by involuntary tics. First choice of treatment has been pharmacological, but recently, behavioural therapy teaching patients to suppress their tics has been introduced. Neuroimaging studies have shown an increased...... activity in the prefrontal cortex, temporal lobes and caudate nucleus, and a decreased activity in globus pallidus and putamen during inhibition of tics. The activity in the frontal lobes changes with age, probably caused by a lack of compensatory hypertrophy. In order to fully understand the mechanism...

  13. Molekylaer patogenese ved monogen og polygen fedme

    DEFF Research Database (Denmark)

    Larsen, Philip J; Echwald, Søren Morgenthaler; Sørensen, Thorkild I A

    2006-01-01

    During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us c...... closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.......During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us...

  14. Lupin i svinefoder mindsker ornelugt

    OpenAIRE

    Hansen, Laurits Lydehøj

    2007-01-01

    Ornelugt i svinekød kan begrænses ved to ugers fodring med 25 pct. lupiner i foderet. Ornelugt er en afvigende lugt og smag, som findes hos 5 til 10 procent af danske hangrise ved en vægt omkring 100 kg. Imidlertid vides det, at sogrise og galte i flere forsøg også har "ornelugt". Eller nærmere betegne, det som nogle forbrugere opfatter som griselugt og afsmag i kødet. Problemet skyldes først og fremmest stoffet skatol.

  15. Addisons sygdom hos femårig

    DEFF Research Database (Denmark)

    Smedegaard, Heidi; Jensen, Rikke Beck; Holm, Kirsten

    2010-01-01

    This case-report presents a 5-year-old girl with gastrointestinal symptoms, who became increasingly confused over the last day before admission. She was believed to be in septic shock or have meningitis and was treated with normal saline infusion, glucocorticoid and antibiotics intravenously. A f...... days later she was diagnosed with primary adrenal insufficiency (Morbus Addison), which is a very rare disorder among children. If untreated, the condition is lethal, and should always be considered as a differential diagnosis in severely ill patients....

  16. Patologisk ankel-arm indeks hos dialysepasienter

    OpenAIRE

    Høva, Gry; Hilde, Kollevold

    2009-01-01

    Pathological ankle-brachial index in dialysispatients Background. Patients in dialysis have an increased risk of cardiovascular disease and death. The purpose of this study was to evaluate the prevalence of pathologic ankle-brachial index (ABI) in a hemodialysis population at Oslo University Hospital Ullevål. Material and methods. For measurement of the ankle- and brachial-blood pressure, we used a Doppler probe and a blood pressure cuff. The measurements were done 1-2 hours into th...

  17. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly....

  18. Spiritualitet som coping hos tibetanske torturoverlevere

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Husum, Kristian

    2010-01-01

    interviewed about their coping mechanisms in overcoming trauma. In all, 36 of these survivors were receiving counselling and both the clients and their 16 professionals were interviewed after the treatment with open-ended questions about what was helpful and not helpful. RESULTS: The torture survivors had...... symptoms of severe traumatisation (Hopkin's Symptom Checklist), but probably not as extensive as torture survivors from other cultures. CONCLUSION: The Tibetan torture survivors use Tibetan Buddhism as an important coping mechanism. Most clients expressed satisfaction with counselling, but criticised...

  19. Ulnarisneuropati hos fjerkræslagteriarbejder

    DEFF Research Database (Denmark)

    Svendsen, Susanne Wulff; Juhl, Anne

    2008-01-01

    Three months after he was employed as a poultry worker, a 48-year-old man developed involuntary jerks of his right first, fourth, and fifth fingers, paraesthesiae, weakness, and eventually wasting of the first dorsal interosseous muscle. His job entailed repetitive lifting of boxes weighing 10-25...

  20. Botulisme hos spaedbørn

    DEFF Research Database (Denmark)

    Hoffmann, Thomas; Mølbak, Kåre; Paerregaard, Anders

    2010-01-01

    Infant botulism is a rare disease that affects infants below the age of 12 months following absorption of neurotoxins produced by ingested Clostridium botulinum spores. The clinical manifestations are caused by symmetrical cranial nerve palsies followed by descending, symmetric flaccid paralysis...

  1. Sundhedsloven og sundhedsydelser hos udokumenterede migranter

    DEFF Research Database (Denmark)

    Aabenhus, Rune; Hallas, Peter

    2012-01-01

    Health-care workers may experience uncertainty regarding legal matters when attending to medical needs of undocumented migrants. This paper applies a pragmatic focus when addressing the legal aspects involved in providing health-care services to undocumented migrants with examples from the Danish...... Health Act and international conventions. The delivery of medical care to vulnerable groups such as pregnant women and children is described.......Health-care workers may experience uncertainty regarding legal matters when attending to medical needs of undocumented migrants. This paper applies a pragmatic focus when addressing the legal aspects involved in providing health-care services to undocumented migrants with examples from the Danish...

  2. Fritids- og sportsaktiviteter hos yngre pacemakerpatienter

    DEFF Research Database (Denmark)

    Mickley, H; Petersen, J

    1989-01-01

    Based on a semistructured questionnaire the consequences of pacemaker treatment on leisure activities in 81 patients aged 20 to 60 years were investigated. At follow up after an average of 33.8 months, 36 of the 72 survivors participated in the following out-of-the-home physical activities...... was restricted mainly due to fear of damaging the battery. Fifteen patients (21%) were members of sport clubs. These results imply that several leisure activities are available for pacemaker patients. In case a particular sport is of interest, this should be taken into account when the sitting of the pacemaker...

  3. Kvinnens overflødighet hos Platon

    Directory of Open Access Journals (Sweden)

    Fredrik Nilsen

    2014-11-01

    Full Text Available The Superfluity of Women in Plato. In her article «Plato’s problematic women» Kristin Sampson argues that Plato has two different views on women in the Republic and the Timaeus respectively. In the Republic Plato operates with some sort of equality of status between the two genders, at least in the leaders’ and the soldiers’ classes, whereas in the mythology of the Timaeus women are depicted as reincarnations of men who earlier had lived an unmoral and bad life. According to my interpretation, these two views must be seen as two aspects of one common Greek thought or, as Vigdis Songe-Møller puts it, one common Greek dream, «the dream of the women’s superfluity». In the Republic Plato tries to rule out differences between genders by making the women as similar to men as possible, while in the Timaeus he describes them as something completely different from the norm, the man, and actually as a punishment to men with bad moral behaviour, something that society ideally should do without.

  4. Primaer psoasabsces hos en ung rask mand

    DEFF Research Database (Denmark)

    Nassehi, Damoun; Galbo, Henrik; Skovsgaard, Flemming

    2008-01-01

    A young male saw his general practitioner because of lower back pain, limpness, nightly sweating, subfebrilia, and weight loss. Further diagnostics showed that he had a primary psoas abscess. Psoas abscesses are categorized as primary and secondary. Primary psoas abscess is a rare disease in Europe...

  5. Propanthelinbromid er effektivt mod savlen hos hunde

    DEFF Research Database (Denmark)

    Gyldenløve, Mette; Thyssen, Jacob P

    2015-01-01

    Hyperhidrosis is a common condition characterized by extensive sweat secretion. Systemic treatment with anticholinergics might prove effective, but patients often suffer from side effects, e.g. dryness of the mouth. We present a clinical case of severe polydipsia in a six-month-old puppy who had...

  6. Svaer metabolisk acidose hos en kronisk alkoholiker

    DEFF Research Database (Denmark)

    Sonne, Morten Egede; Rudolph, Søren Finnemann; Pott, Frank Christian

    2008-01-01

    Severe metabolic acidosis is associated with poor prognosis. We present a patient with profound alcohol and starvation-related combined lactic and keto acidosis (lactate = 29 mM; pH = 6.83) who made a good recovery following 18 hours of intensive care therapy. A brief summary of the proposed...... mechanism by which these metabolic derangements develop is presented....

  7. Durability of shrink joints; Bestaendighet hos krympskarvar

    Energy Technology Data Exchange (ETDEWEB)

    Forsaeus Nilsson, Stefan; Saellberg, Sven-Erik

    2007-07-01

    About one third of all joint failures are caused by shrink seals losing adhesion, according to statistics from the Swedish District Heating Association. The present project was initiated upon request from the Authorisation Board of the Swedish District Heating Association in order to investigate the potential to enhance the quality of shrink joints. The purpose has been to provide a screening of the key properties of the joint systems currently available on the market. The aim has been to facilitate the choice of right materials and constructions to achieve the best functionality and cost effectiveness. The project has comprised a compilation of the views from industry representatives from manufacturers of shrink and sealing materials, pipe producers, joint contractors and district heating companies, and an experimental study where a number of joints were evaluated with respect to tightness and strength. The following joint systems took part in the investigation: Logstor SX; Canusa SuperCase; Raychem RayJoint; Powerpipe DTK with external seal Nitto NeoCover 1150 in one end and Raychem TPSM in the other; Logstor B2S med external seal Canusa KLD in one end and Raychem TPSM in the other. The joints were installed on pipes of diameters 160 mm and 450 mm. The installation was done under cold and dirty conditions, to simulate a field like worst-case scenario. After the installation, the joints were tested with respect to tightness. Peel strength and shear strength were evaluated before and after thermal ageing in +50 deg C for 70 days. Mechanical tests and ageing followed standardised procedure in EN 12068. A study of the shrink force relaxation in crosslinked and non-crosslinked polyethylene shrink sleeves was undertaken, by shrinking them onto aluminium cylinders and storing them in room temperature for about 2000 hours. The results show that it is clearly possible to install excellent shrink joints also under difficult conditions. In addition, thermal ageing does not automatically lead to any dramatic changes in material properties. Of the tested variants, all but one was completely tight and the mechanical strength levels were in line with what the manufacturers state in their data sheets for most of the joints. The measured shrink forces show that relaxation is not a big problem. The material in the joint sleeve will continue to strive towards it non-expanded state of equilibrium, and for the non-crosslinked samples, this actually resulted in an increase in shrink force over time. Since the materials and constructions do work, one may indirectly conclude that the problems are mainly caused by the installation, which, in turn, is likely to a large extent a consequence of difficult working conditions and demanding installation procedures. According to experience, the sealing materials are decisive for the ease of installation. From the fitter's point of view, the sealing material should be soft (more forgiving) and fibre reinforced (easier to handle) and it should come in wide strips (easier to apply). When it comes to sleeves, the shrinking work is faster with crosslinked material (PEX). An important observation is also that sleeves with built-in sealant and/or adhesive are harder to keep clean at the work site. Hence, the most important thing is that the installation is done in a proper manner and that appropriate conditions for the fitter to achieve this is provided at the work site. It is hard to single out the best or the worst joint system, but some recommendations may be given: Remember to depressurise the joint during shrinking to avoid unnecessary pressure loads on the seal. Use a sleeve of crosslinked polyethylene if a fast installation is important. If non-crosslinked sleeves are used, choose a double expanded variant. Use a sealing material with easy handling and forgiving characteristics, e.g., the type used for Nitto NeoCover or Raychem TPSM. If extra strength is needed, use a stronger sealant, such as, e.g., a mastic/hotmelt mix such as that used in Canusa KLD. Please note, though, that high strength does not automatically imply good tightness

  8. Komplikationer hos gravide med polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Tolstrup, Johan; Jónsdóttir, Fjóla; Ring, Charlotte Mumm

    2016-01-01

    Pregnant women with polycystic ovary syndrome (PCOS) are at increased risk of pregnancy-related disorders such as gestational diabetes (GDM), gestational hypertension and preeclampsia in the 2nd and 3rd trimester. In addition, the risk of preterm birth, children who are small and large...... for gestational age, caesarean section and poorer neonatal outcome seem to be elevated, however with less clear evidence. Except for the screening for GDM, there is no evidence of a benefit of increased surveillance during pregnancy for women with PCOS....

  9. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, A.C.; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    . MATERIAL AND METHODS: Surgeons performing UI procedures were identified and mailed a questionnaire in 2007 concerning 2006. Questions included specialisation, number of procedures, type of surgery, complications and attitude towards learning surgery and maintaining a sufficient level of routine. RESULTS...... slings. This study did not allow for a quantitative assessment of complications. The attitude was that 10-25 operations are needed to learn the procedure, and that > 10 operations per year are needed to maintain a sufficient level of routine. CONCLUSION: Practice and attitudes among urinary incontinence......INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons...

  10. Naturligt forekommende oseltamivirresistens hos influenza A

    DEFF Research Database (Denmark)

    Madsen, Laura; Nielsen, Alex; Lundgren, Jens

    2010-01-01

    During the last two influenza seasons, one of the predominant influenza A types (H1N1) has developed complete resistance to oseltamivir, the primary treatment option. The virus does, however, remain sensitive to zanamavir and amantadine. There is no unequivocal explanation for this slide...... in the development of resistance. The best prevention strategy remains vaccination of the general population to avoid immunity. Future antiviral treatment calls for knowledge about resistance to existing types of influenza and the availability of all three types of antiviral medication....

  11. Naturligt forekommende oseltamivirresistens hos influenza A

    DEFF Research Database (Denmark)

    Madsen, Laura; Nielsen, Alex; Lundgren, Jens

    2010-01-01

    in the development of resistance. The best prevention strategy remains vaccination of the general population to avoid immunity. Future antiviral treatment calls for knowledge about resistance to existing types of influenza and the availability of all three types of antiviral medication.......During the last two influenza seasons, one of the predominant influenza A types (H1N1) has developed complete resistance to oseltamivir, the primary treatment option. The virus does, however, remain sensitive to zanamavir and amantadine. There is no unequivocal explanation for this slide...

  12. MBHI hos patienter med kroniske rygsmerter

    DEFF Research Database (Denmark)

    Simonsen, Erik; Kastberg, S.; Jensen, Hans Henrik

    1991-01-01

    Studied the predictive validity of the MBHI (T. Millon et al, 1982) and analyzed the differences in personality and attitudes between patients with chronic lower-back pain and patients with acute pain. Human Ss: 26 male and female adults (aged 28–60 yrs) (chronic lower-back pain); 24 male and fem...... of treatment to determine the extent of the success of the therapy. The actual success of the therapy was compared with the predictions for success based on the MBHI results. (English abstract) (PsycINFO Database Record (c) 2012 APA, all rights reserved)...

  13. Hepatitis C hos børn

    DEFF Research Database (Denmark)

    Christensen, Vibeke Brix; Nordly, Sannie Brit; Fischler, Bjørn

    2014-01-01

    Chronic hepatitis C (HCV) infection has a prevalence of 2-3% worldwide. The vertical transmission rate is approximately 5%. There is no evidence to recommend abstinence from breastfeeding or elective C-section to prevent transmission. In children, the natural history of HCV infection is typically...

  14. Hepatitis B hos børn

    DEFF Research Database (Denmark)

    Christensen, Vibeke Brix; Nordly, Sannie Brit; Kjær, Mette

    2014-01-01

    Chronic hepatitis B (HBV) infection is seen in 400 million persons worldwide. HBV is transmitted vertically or horizontally by infected blood and body fluids. An effective vaccine exists. Most children develop a chronic HBV infection if infected early in life. They are often in an immune-tolerant......Chronic hepatitis B (HBV) infection is seen in 400 million persons worldwide. HBV is transmitted vertically or horizontally by infected blood and body fluids. An effective vaccine exists. Most children develop a chronic HBV infection if infected early in life. They are often in an immune...

  15. Odontogent myksom i maksillen hos et barn

    DEFF Research Database (Denmark)

    Danielsson, Lina Isabella; Jakobsen, John; Thygesen, Torben H

    2014-01-01

    exclusively in the maxilla. Orbital involvement is very rare, and to our knowledge reconstruction with a Medpore sheet has not previously been reported. At post-operative follow-up normal eye function and an excellent cosmetic result was observed. OM should be considered in a midfacial mass....

  16. Ideologi og virkelighed hos Hartvig Frisch

    DEFF Research Database (Denmark)

    Rasmussen, Anders Holm

    Bogen beskriver, hvorledes danske socialdemokratiske politiker og professor i klassisk filologi, Hartvig Frisch, anvendte sin indsigt i antikkens historiografi og filosofi i sin samtidige formulering af en socialdemokratisk politik....

  17. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, Astrid Cecilie; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    (TVT) was the preferred sling in 2006. A total of 20 (47%) UI surgeons used only TVT, seven (17%) only transobturator slings (TOS) and 15 (36%) both TVT and TOS. Only 11 (24%) performed > 25 TVT per year and 11 (27%) performed > 25 TOS per year. In all, UI surgeons had experience with ten different...

  18. Primaer psoasabsces hos en ung rask mand

    DEFF Research Database (Denmark)

    Nassehi, Damoun; Galbo, Henrik; Skovsgaard, Flemming

    2008-01-01

    and North America. It is primarily seen in young men, and the classical symptom-triad is: fever, back pain, and limpness. The golden standard diagnostic tool is computed tomography, and treatment involves appropriate antibiotics, which can be combined with percutaneous drainage....

  19. Erhvervsbetinget eksem hos fynske gartnere og gartnerimedhjaelpere

    DEFF Research Database (Denmark)

    Paulsen, E; Søgaard, J; Andersen, Klaus Ejner

    1998-01-01

    -sectional study, based on a postal questionnaire and subsequent patch testing of selected persons was carried out in 1958 gardeners. The response rate was 84.6%, and among 250 persons patch tested the most frequently sensitizing occupational allergens were plants of the Compositae family and the fungicide captan....... Allergic occupational contact dermatitis was suspected in 43 persons (17%). Irritant eczemas outnumbered allergic eczemas and both were most often caused by plants. The lifetime prevalence of occupational dermatitis was 19.6%. Occupational mucosal symptoms, working with Compositae and training...

  20. Dermatologiske reaktioner hos patienter i antineoplastisk behandling

    DEFF Research Database (Denmark)

    Prasad, Sumangali Chandra; Vestergaard, Hanne; Bygum, Anette

    2014-01-01

    Every year more than 33,000 Danish patients are treated with traditional chemotherapy or targeted therapy against cancer. Cutaneous side effects to these therapies are common and may contribute significantly to the morbidity, but rarely to the mortality of the patients undergoing these treatments....... We present the most classical types of drug rashes associated with antineoplastic therapy. Haematologists, oncologists and dermatologists should be aware of these reactions and early recognition and management is important for providing optimal care....

  1. Abort hos får

    DEFF Research Database (Denmark)

    Agerholm, Jørgen Steen; Fog-Larsen, Anne Marie; Jensen, Tim K.

    2006-01-01

    Forårsages ofte af mikroorganismer, der naturligt forekommer i dyrenes miljø! For at undgå smitte til andre drægtige får bør aborterede fostre og efterbyrden straks fjernes fra folden og moderfåret isoleres....

  2. Traumatiske reaksjoner hos tolker i offentlig sektor

    Directory of Open Access Journals (Sweden)

    Daniela Feistritzer

    2015-01-01

    Full Text Available This article aims to see how traumatic reactions may influence public service interpreters in their interpreting performance. It looks at relevant research results and refers to reflective reports and written examinations about secondary traumatic stress and other psychological reactions written by interpreters that attended a one-semester study programme in public service interpreting at Telemark University College in 2004. The article is divided into three parts starting with a definition of the key concept used to describe traumatic reactions that may arise when meeting traumatised people. Thereafter it briefly presents neurophysiologic research results that show a relation between emotional reactions and the interpreting process. Part two describes the content of the above mentioned one semester programme in interpreting that included the topic of interpreting in emotional challenging situations and part three connects the students’ reflections to the key concepts around traumatic reactions and analyses how this topic may be integrated in interpreting studies.

  3. Kryptorkisme hos drenge med anal atresi

    DEFF Research Database (Denmark)

    Cortes, Dina; Thorup, J M; Nielsen, Ole Henrik

    1996-01-01

    In a retrospective study of the case reports of 136 boys who were operated on for an imperforate anus and who survived at least 18 months, cryptorchidism was the most common associated anomaly, involving 26 cases (19%). The higher the level of the anorectal malformations, the higher was the incid...

  4. Utopi og rejse hos Jens Baggesen

    DEFF Research Database (Denmark)

    Sandberg, A.

    2007-01-01

    En analyse af, hvordan det kosmopolitiske oplysningsideal ændrer sig fra Jens Baggesens dansksprogede rejseskildring Labyrinten til hans tysksprogede epos Oceania i lyset af den begyndende nationalisme. Udgivelsesdato: Jahrgang 28......En analyse af, hvordan det kosmopolitiske oplysningsideal ændrer sig fra Jens Baggesens dansksprogede rejseskildring Labyrinten til hans tysksprogede epos Oceania i lyset af den begyndende nationalisme. Udgivelsesdato: Jahrgang 28...

  5. PTSD hos ældre efterladte

    DEFF Research Database (Denmark)

    O'Connor, Maja

    2009-01-01

    Intro: Tab af ægtefælle i alderdommen kan være en traumatisk begivenhed med reaktioner og symptomer på linje med dem, man nogle gange ser efter overfald, ulykker og naturkatastrofer. Det slår en ny undersøgelse fast. Udgivelsesdato: Maj 2009...

  6. Stumpe nyretraumer hos børn

    DEFF Research Database (Denmark)

    Bjørsum-Meyer, Thomas; Rasmussen, Lars; Lund, Lars

    2017-01-01

    Lesion of the kidney is found in 10% of children with a blunt abdominal trauma. Conservative treatment regimens are generally accepted for mild traumatic renal injury. No consensus exists regarding treatment of more severe traumatic renal lesion in children. Strategy for imaging and follow-up has...... also been unclear. Recent studies suggest successful conservative treatment of severe renal injury without complications. We present existing knowledge on treatment and follow-up in children with renal trauma....

  7. Mundhulens mikroflora hos patienter med marginal parodontitis

    DEFF Research Database (Denmark)

    Larsen, Tove; Fiehn, Nils-Erik

    2011-01-01

    ikke dyrkes. Viden om samspillet mellem bakterierne i plakken, som er en biofilm, er ligeledes under hastig udvikling. Dette betyder, at vi i de kommende år løbende må revidere vores forståelse af marginal parodontitis’ mikrobiologi. I nærværende oversigtsartikel præsenteres den eksisterende viden...

  8. Immunmedieret perikarditis hos patient med meningokokmeningitis

    DEFF Research Database (Denmark)

    Fuglsang Hansen, Janne; Johansen, Isik Somuncu

    2014-01-01

    Extrameningial manifestations in patients with meningococcal meningitis are rare. One of these manifestations is immune-mediated or purulent pericarditis. We present a case where a patient with meningococcal meningitis developed pericarditis on the 11th day after admission. A pericardial puncture...... was performed but the pericardial fluid regenerated after two days despite antibiotic treatment. The pericardial fluid showed no bacterial growth and PCR for bacterial DNA was negative. Subsequent steroid treatment proved to be effective, indicating a case of immune-mediated pericarditis....

  9. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...... treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly....

  10. Demenslidelser hos ældre tyrkiske indvandrere

    DEFF Research Database (Denmark)

    Rosenbaum, B.; Kristensen, M.; Schmidt, J.

    2008-01-01

    need for a nursing home. MATERIAL AND METHODS: With the help of an interpreter, the Turkish population of elderly (> 60 years old) in the municipality of Ishoj was interviewed about educational-, working- and health conditions. In addition to MMSE and semi-structured interviews, the ICD-10 criteria......INTRODUCTION: The health condition in a population of elderly Turkish immigrants is investigated with special focus on dementia conditions. The possibility to use the screening test Mini Mental State Examination (MMSE) in relation to the investigated population is evaluated as well as their future...... were used in diagnosing dementia conditions. RESULTS: We found an increased frequency of dementia conditions (13,3%) compared to the expected prevalence of 7% in the Danish population. Furthermore, we found an increased frequency of diabetes type-2. The use of MMSE as a guideline instrument...

  11. Astma hos børn

    DEFF Research Database (Denmark)

    Bønnelykke, Klaus; Pedersen, Søren; Rubak, Sune Leisgaard Mørck

    2013-01-01

    These clinical guidelines were developed by the Danish Pediatric Asthma Center in collaboration with the Danish Paediatric Society. Key messages in the guidelines are: 1) Inhaled steroids are the most effective preventive medication and are first choice in children with persistent symptoms. 2) Th...

  12. Obstetriske komplikationer hos kvinder med endometriose

    DEFF Research Database (Denmark)

    Berlac, Janne Foss; Hartwell, Dorthe; Langhoff-Roos, Jens

    2014-01-01

    Approximately 5-10% of the women in the reproductive age are afflicted with endometriosis and many become pregnant after fertility treatment. Women with endometriosis seem to have an increased risk of placental complications, bleeding in pregnancy and during labour as well as possible increased r...

  13. Uppfattningar om neuropsykiatriska diagnoser hos barn

    OpenAIRE

    Hellqvist, Eva-Lotta

    2010-01-01

    Children become diagnosed with neuropsychiatry diagnostic. The diagnostic of children is critiqued from. The national board of health and welfare because the child psychiatric clinics differ in the reliability of diagnostic. This is a problem both in the same clinic and between clinics. The purpose is to investigate if parents of children with neuropsychiatry diagnostic consider that the diagnostic criteria were met when the child was diagnosed. The method was first a pilot study with surveys...

  14. Cytomegalovirus-colitis hos immunkompetent ung mand

    DEFF Research Database (Denmark)

    Rasmussen, Eva; Grønbaek, Karin; Linnemann, Dorte

    2009-01-01

    A healthy young man was hospitalized due to fever, malaise and bloody stools for three weeks. The patient had a primary CMV infection based on biochemical, serological and ultrasonic results, and a colonoscopy was consistent with left-sided CMV colitis. He recovered spontaneously, though haematoc...

  15. Kryptorkisme hos drenge med anal atresi

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Nielsen, O H

    1996-01-01

    with urological and with T10-S5 vertebral malformations and dysplasias. Recognition of this association is probably new. The histopathological findings of testicular biopsy specimens and the location of the undescended testes in patients with an imperforate anus showed the same pattern as seen in undescended...... testes from patients with cryptorchidism only. These findings, together with the existing literature on the subject, indicate that further studies on the association of cryptorchidism, urological, and T10-S5 vertebral malformations and dysplasias may be important for a better understanding...

  16. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...

  17. Propofolinfusionssyndromet hos børn

    DEFF Research Database (Denmark)

    Hansen, Tom G

    2005-01-01

    Propofol infusion syndrome, characterised by cardiovascular collapse, metabolic acidosis, hepatomegaly, renal failure and rhabdomyolysis, is a rare and often fatal syndrome seen in critically ill children undergoing long-term propofol sedation. Propofol may impair mitochondrial free fatty acid...

  18. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, Astrid Cecilie; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons....... MATERIAL AND METHODS: Surgeons performing UI procedures were identified and mailed a questionnaire in 2007 concerning 2006. Questions included specialisation, number of procedures, type of surgery, complications and attitude towards learning surgery and maintaining a sufficient level of routine. RESULTS...... slings. This study did not allow for a quantitative assessment of complications. The attitude was that 10-25 operations are needed to learn the procedure, and that > 10 operations per year are needed to maintain a sufficient level of routine. CONCLUSION: Practice and attitudes among urinary incontinence...

  19. Sundhedsloven og sundhedsydelser hos udokumenterede migranter

    DEFF Research Database (Denmark)

    Aabenhus, Rune Munck; Hallas, Peter

    2012-01-01

    Health-care workers may experience uncertainty regarding legal matters when attending to medical needs of undocumented migrants. This paper applies a pragmatic focus when addressing the legal aspects involved in providing health-care services to undocumented migrants with examples from the Danish...

  20. Periacetabulaer osteotomi og hoftedysplasi hos yngre voksne

    DEFF Research Database (Denmark)

    Troelsen, Anders; Søballe, Kjeld

    2009-01-01

    The periacetabular osteotomy is recognized as the surgical treatment of choice in young adults with symptomatic hip dysplasia. The procedure is performed to delay or prevent the development of osteoarthritis. The procedure has the ability to improve function and preserve hip joints in > 80...

  1. Obstetriske komplikationer hos kvinder med endometriose

    DEFF Research Database (Denmark)

    Berlac, Janne Foss; Hartwell, Dorthe; Langhoff-Roos, Jens

    2014-01-01

    Approximately 5-10% of the women in the reproductive age are afflicted with endometriosis and many become pregnant after fertility treatment. Women with endometriosis seem to have an increased risk of placental complications, bleeding in pregnancy and during labour as well as possible increased...... risk of pre-eclampsia, preterm birth and low birthweight. Large epidemiological studies are needed to clarify the magnitude of these risks in order to define the appropriate level of proactive management of pregnant women with endometriosis....

  2. Spiritualitet som coping hos tibetanske torturoverlevere

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Husum, Kristian

    2010-01-01

    INTRODUCTION: There is solid documentation for the positive relationship between spirituality and health, but few examples of how this link may be used in projects of rehabilitation after war, civil conflicts and natural disasters. One such example is the Danida funded Tibetan Torture Program...

  3. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, Astrid Cecilie; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    : In total, 94 operating gynaecologists and urologists were identified, 63 responded (71%) of whom 49 (78%) performed UI surgery. UI surgeons were gynaecologists 43 (88%) of these 24 (49%) were urogynecologists (working more than 50% with urogynecology) and five (10%) urologists. Tension-free Vaginal Tape...

  4. Laryngeal sarkoidose hos 13-årig

    DEFF Research Database (Denmark)

    Herlow, Louise Buchreitz; Rasmussen, Niels

    2010-01-01

    Sarcoidosis is a chronic granulomatous disease of unknown pathogenesis. It can affect numerous organs but most commonly involves the respiratory tract. On rare occasions it only involves the larynx. We describe a case of isolated laryngeal sarcoidosis in a teenage girl with symptoms of hoarseness...

  5. Seksuel funktion hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E; Stenager, E N; Jensen, Knud

    1997-01-01

    Sexual dysfunction is known to occur in multiple sclerosis (MS). The purpose of the study is to describe the change in sexual function and symptoms in a five year follow-up study. Forty-nine patients (27 females, 22 males) with definite MS were interviewed and examined. The number of patients...

  6. Svaer metabolisk acidose hos en kronisk alkoholiker

    DEFF Research Database (Denmark)

    Sonne, Morten Egede; Rudolph, Søren Finnemann; Pott, Frank Christian

    2008-01-01

    Severe metabolic acidosis is associated with poor prognosis. We present a patient with profound alcohol and starvation-related combined lactic and keto acidosis (lactate = 29 mM; pH = 6.83) who made a good recovery following 18 hours of intensive care therapy. A brief summary of the proposed mech...

  7. Laparoskopisk splenektomi for hereditaer sfaerocytose hos born

    DEFF Research Database (Denmark)

    Petersen, C.R.; Bulut, O.; Jess, P.

    2008-01-01

    Based on the positive international experience with laparoscopic splenectomy on a large number of patients since 1991, we treated two teenagers with symptomatic hereditary spherocytosis and moderate splenomegaly. Both operations and postoperative courses were uneventful, and the children had...

  8. Kronisk hoste hos børn

    DEFF Research Database (Denmark)

    Grarup, Pernille Abildgaard; Pedersen, Juri Lindy

    2015-01-01

    Cough in children is a common problem of various aetiologies. In the presence of specific findings diagnostics may be easy, but often the symptoms are few and unclear. Management involves specific diagnosing and it should be considered if the cough is acute, prolonged or chronic. The diagnosis...... depends on the quality of the cough evaluated as dry cough or wet, productive cough. Trials of treatment are often used to make a diagnosis, and any trial should be time-limited because natural resolution of cough is so common. Finally, giving thorough information to parents is crucial....

  9. Type 2-diabetes hos etniske minoriteter

    DEFF Research Database (Denmark)

    Zander, Mette; Hansen, Caroline Raun; Koefoed, Birgitte Gade

    2012-01-01

    and high catch up weight as well as socio-economic factors. Ethnic minorities are heterogeneous, and individual initiatives within the different groups are needed. The evidence regarding the effect of initiatives targeted at ethnic minorities in Denmark is sparse. In future, clinically controlled studies...

  10. Nekrotiserende fasciitis hos børn

    DEFF Research Database (Denmark)

    Jensen, Karsten Gjessing; Kristensen, Kim

    2009-01-01

    Necrotizing fasciitis (NF) is a serious condition with infection of the muscular fascia causing rapidly spreading necrosis. NF rarely affects children, and we here report two paediatric cases of NF. The first developed NF after a joint puncture, the other after surgical extirpation of a lymph node...

  11. Svaer metabolisk acidose hos en kronisk alkoholiker

    DEFF Research Database (Denmark)

    Sonne, Morten Egede; Rudolph, Søren Finnemann; Pott, Frank Christian

    2008-01-01

    Severe metabolic acidosis is associated with poor prognosis. We present a patient with profound alcohol and starvation-related combined lactic and keto acidosis (lactate = 29 mM; pH = 6.83) who made a good recovery following 18 hours of intensive care therapy. A brief summary of the proposed...

  12. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    INTRODUCTION: The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet. MATERIALS AND METHODS: The study was a retrospective review...... of patients discharged with the diagnostic codes ventricular tachycardia, ventricular fibrillation or premature ventricular contractions with cardiomyopathy as the presumed aetiology. Patients discharged during a period of 6 years and 5 months were included in the study. The patients were characterized...... by disease, gender, age, previous cardiac arrest and treatment with implantable cardioverter-defibrillator (ICD). RESULTS: 993 patients were screened and 128 patients with cardiomyopathy were identified, corresponding to 13% of the screened patients. 58 (45%) of the patients had dilated cardiomyopathy (DCM...

  13. Type 2-diabetes hos etniske minoriteter

    DEFF Research Database (Denmark)

    Zander, Mette; Hansen, Caroline Raun; Koefoed, Birgitte Gade

    2012-01-01

    In general, type 2 diabetes is more common among immigrants than among the inhabitants with a Western background. The higher prevalence among ethnic minorities is probably due to a complex correlation between genetic factors, diet, exercise, linguistic and cultural obstacles, low birthweight...

  14. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    INTRODUCTION: The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet. MATERIALS AND METHODS: The study was a retrospective review...... of patients discharged with the diagnostic codes ventricular tachycardia, ventricular fibrillation or premature ventricular contractions with cardiomyopathy as the presumed aetiology. Patients discharged during a period of 6 years and 5 months were included in the study. The patients were characterized...... with ARVC, 70% of the patients with HCM and 59% of the patients with DCM. Only 5 patients had previous cardiac arrest without reversible cause. CONCLUSION: The study shows that cardiomyopathies are relatively frequent causes of ventricular tachyarrhythmias in patients discharged from a specialised...

  15. Problemer med primakin-recidivprofylakse hos malariapatienter

    DEFF Research Database (Denmark)

    Rønn, A M; Bygbjerg, Ib Christian

    1993-01-01

    -resistant malaria have been observed. The side effects of primaquine are mainly gastrointestinal. Primaquine may also cause serious toxic side effects, including methaemoglobin formation and haemolytic anaemia, especially in individuals with erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. We...

  16. Intervertebral diskitis hos børn

    DEFF Research Database (Denmark)

    Benhassen, Leila Louise; Balslev, Thomas; Gammelgaard, Lise

    2016-01-01

    but infectious, and inflammatory aetiologies have been suggested. Diagnostic golden standard is magnetic resonance imaging. The treatment is immobilization, anti-inflammatory drugs and often antibiotics. Early treatment is important to reduce the risk of complications such as nerve damage and spine fusion....

  17. Obstetriske komplikationer hos kvinder med endometriose

    DEFF Research Database (Denmark)

    Berlac, Janne Foss; Hartwell, Dorthe; Langhoff-Roos, Jens

    2014-01-01

    Approximately 5-10% of the women in the reproductive age are afflicted with endometriosis and many become pregnant after fertility treatment. Women with endometriosis seem to have an increased risk of placental complications, bleeding in pregnancy and during labour as well as possible increased r...... risk of pre-eclampsia, preterm birth and low birthweight. Large epidemiological studies are needed to clarify the magnitude of these risks in order to define the appropriate level of proactive management of pregnant women with endometriosis....

  18. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...... treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly...

  19. Demens hos personer med Downs syndrom

    DEFF Research Database (Denmark)

    Salem, Lise Cronberg; Jørgensen, Kasper

    2014-01-01

    In developed countries the population of elderly people with Down syndrome expands resulting in an increasing incidence of age-related diseases, including dementia. The assessment of dementia in individuals with intellectual disability is often complicated due to large intra-individual variability...... in cognitive functioning prior to dementia and to lack of standardised measures to detect dementia. Structured observations of symptoms of dementia and assessment techniques tailored for people with intellectual disability are increasingly needed....

  20. Botulisme hos spaedbørn

    DEFF Research Database (Denmark)

    Hoffmann, Thomas; Mølbak, Kåre; Paerregaard, Anders

    2010-01-01

    of voluntary muscles. Presenting symptoms include constipation, lethargy, mydriasis and ptosis. The diagnosis is made on the basis of clinical examination and confirmed by isolating the toxin in serum or stools. Treatment consists of supportive intensive care and treatment with antitoxins....

  1. Smitteopsporing efter fund af lungetuberkulose hos flyrejsende

    DEFF Research Database (Denmark)

    Lynggaard, Charlotte Duch; Eriksen, Nina Marie Birk; Andersen, Peter Henrik

    2011-01-01

    During international air travel individuals stay in a closed environment which might lead to a risk of transmission of respiratory infectious diseases such as tuberculosis carried by infectious travellers. Tracing exposed passengers requires international cooperation and assistance from relevant...... authorities. We describe an investigation among fellow passengers to a traveller with sputum positive pulmonary tuberculosis....

  2. Nyt koncept forebygger sundhedsproblemer i mælkeproduktionen

    DEFF Research Database (Denmark)

    Rothmann Holm, Janne

    2017-01-01

    Overvågning: Ved brug af HACCP konceptet kan landmænd opdage og løse sundhedsproblemer hos køer på et tidligt tidspunkt. I EU projektet GplusE arbejder man på at tilpasse HACCP konceptet til brug for overvågning af sundheden i mælkeproduktionen.......Overvågning: Ved brug af HACCP konceptet kan landmænd opdage og løse sundhedsproblemer hos køer på et tidligt tidspunkt. I EU projektet GplusE arbejder man på at tilpasse HACCP konceptet til brug for overvågning af sundheden i mælkeproduktionen....

  3. An international business blunder - Fennia 1913-1916

    DEFF Research Database (Denmark)

    Pedersen, Kurt; Sørensen, Peter; Strandskov, Jesper

    2008-01-01

    En fremstilling af Otto Mønsted A/S finske datterselskab, født 1913 og afgået ved en kompliceret død tre år senere. Dertil en analyse på basis af begreber hentet hos Michael Porter samt Bartlett, Ghoshal og Nohria af ledelsesmæssige fejldispositioner.......En fremstilling af Otto Mønsted A/S finske datterselskab, født 1913 og afgået ved en kompliceret død tre år senere. Dertil en analyse på basis af begreber hentet hos Michael Porter samt Bartlett, Ghoshal og Nohria af ledelsesmæssige fejldispositioner....

  4. Predicting effects and risk of relapse into depression: The Danish ECT/MRI project

    DEFF Research Database (Denmark)

    Gbyl, Krzysztof; Rosenberg, Raben; Larsson, Henrik Bo Wiberg

    Formål: Vi ønsker at undersøge hjernen hos patienter med svær depression før og efter elektrokonvulsiv terapi (ECT), samt ved en kontrol efter 6 måneder med det formål at: 1. undersøge hjernevævet så en evt. skadelig effekt af ECT-behandling kan udelukkes 2. belyse mekanismerne bag ECT for at fin...

  5. Long-term risk of atrial fibrillation after the death of a partner

    DEFF Research Database (Denmark)

    Graff, Simon; Fenger-Grøn, Morten; Christensen, Bo

    2016-01-01

    Dette studie viser, at mennesker, som for nylig har mistet deres partner, har en øget risiko for at udvikle uregelmæssig hjerterytme i op til ét år efter tabet. Den øgede risiko forekommer i op til et år efter tabet, og den største risiko ses hos efterladte på under 60 år og ved uventede dødsfald...

  6. Perceived health and risk of undernutrition: a comparison of different nutritional screening results in older patients

    OpenAIRE

    Söderhamn, Ulrika; Flateland, Sylvi; Jessen, Liss; Söderhamn, Olle

    2011-01-01

    Artikkelen rapporterer en studie hvor hensikten var å sammenligne screeningsresultater ved bruk av ulike ernæringsscreeninginstrumenter hos eldre pasienter i institusjon. To compare screening results using different nutritional screening instruments with respect to nutritional risk and associations with perceived health and health-related issues in a group of older hospital patients. The association between lower perceived health and nutritional risk in older people is widely known. It is ...

  7. Skader ved brug af løbehjul. Behandlet ved Odense universitetshospital 1996-2001

    DEFF Research Database (Denmark)

    Larsen, Michael Hareskov; Nielsen, Henrik Toft; Larsen, Søren Erik

    2002-01-01

    Since the beginning of the nineties, skate-boards, in-liners, roller skates, and during the past years non-powered scooters have gained increasing popularity. This surge of enthusiasm has resulted in an increasing number of injuries involving scooters.......Since the beginning of the nineties, skate-boards, in-liners, roller skates, and during the past years non-powered scooters have gained increasing popularity. This surge of enthusiasm has resulted in an increasing number of injuries involving scooters....

  8. Tegn på læring ved bruk av interaktive matematikkutstillinger ved vitensenter

    Directory of Open Access Journals (Sweden)

    Nils Kr. Rossing

    2016-04-01

    Full Text Available Interactive exhibits at science centres are believed to have a learning effect on visitors. This study investigates two interactive exhibits concerning mathematics at the Science centre in Trondheim, Norway, to what extent they appeal to the audience, and contributes to constructive thought processes that provide for learning. I was also looking for characteristics of the exhibits that might obstruct such thought processes. During the study we observed more than 170 visitors while they used the two exhibits. In addition I observed and interviewed seven teenagers hired specifically to work with the exhibits. Since the audience are completely free to use the exhibits as they like, it is assumed that there is a high correlation between time spent at the exhibits and public involvement. By measuring the average time for every age group, it was found that the exhibits engaged teenagers and adults to a high degree. Also children below 13 years of age used the exhibits diligently, but then in other ways than intended. Some major obstacles that the design of the exhibits let in the way of creating constructive thought processes among the audience were identified. For example, it was found that removing the time limitation of solving tasks and giving the audience the greatest possible transparency and control over the exhibits, a better basis for discussions and reflections was laid. This is an important premise for learning. Furthermore, changes in conditions were made in order to encourage the audience to try out new strategies.

  9. Kodein og amning – en farmakogenetik case

    DEFF Research Database (Denmark)

    2010-01-01

    sygdomme hos drengen. Derimod fandt man ved de toksikologiske test postmortem 70ng/mL morfin og 5.9 μg/mL paracetamol i drengens blod. Den terapeutiske morfin-koncentration i plasma for smertestillede effekt er 10-12 ng/mL hos spædbørn, og efter amning hos en mor, der får 60 mg kodein som smertestillende...... efter fødslen, er maksimal morfin-koncentration i plasma 2.2 ng/mL hos spædbørn. En gennemgang af moderens medicinering postpartum viste, at hun havde fået udskrevet tablet Tylenol® 3, der er en kombination af kodein 30 mg og paracetamol 500 mg, med doseringen 2 tabletter 2 gange daglig. Med da kvinden...... følte sig forstoppet og svimmel, halverede hun dosis allerede to dage efter fødslen. Da problemerne med drengens evne til at die opstod, malkede kvinde ud og gemte mælken i fryseren. Mælken viste sig efterfølgende at indeholde 87 ng/mL morfin. Spørgsmål: Drengen døde af morfinforgiftning. Men hvad er...

  10. Juvenil idiopatisk artritt – Hva en tannlege bør vite

    DEFF Research Database (Denmark)

    Kristensen, Kasper Dahl; Stoustrup, Peter Bangsgaard

    2015-01-01

    Juvenil idiopatisk artritt (barneleddgikt) er en sykdom karakterisert ved nedsatt mobilitet og leddsmerter av lengre enn seks ukers varighet hos barn under 16 år. Der finnes cirka 1000 barn i Norge med diagnosen. Affisering av kjeveleddene før ansiktsveksten opphører kan medføre craniofaciale vek......, symptomer, klinisk utseende, diagnostikk, behandlingsmuligheter samt andre tannlegerelevante forhold. Kjeveleddet spiller en sentral rolle for mange pasienter med juvenil idiopatisk artritt og vil bli beskrevet i større detalj....

  11. Computerstyret Automatisk Screening for Livmoderhalskræft

    DEFF Research Database (Denmark)

    Bjerregaard, Beth; Anthonisen, Bette; Jantzen, Jan

    1999-01-01

    for livmoderhalskræft med samme eller bedre diagnostiske kvalitet and den nuværende manuelle screening og til en salgspris, så der spares ressourcer. Projektet er et offentligt/privat udviklingsprojekt støttet af Erhvervsfremme Styrelsen. Projektet er et lærestykke i samarbejde mellem forskellige instanser ved opstart...... pilotundersøgelse viser, at de allerede tilgængelige teknikker og viden hos både den offentlige og den private part er velegnede til at løse opgaven....

  12. Konkursloven med kommentarer

    DEFF Research Database (Denmark)

    Petersen, Lars Lindencrone; Ørgaard, Anders

    konkursramt selskab forbud mod at drive virksomhed i selskaber med begrænset hæftelse (og i særlige tilfælde også virksomhed med personlig hæftelse), hvis der er konstateret visse bebrejdelsesværdige forhold hos medlemmer af ledelsen. Ved loven blev § 13 b, stk. 1, ændret, og der blev indsat nyt stk. 4 i § 15...... og nyt stk. 3 i § 125 samt nye §§ 157-169 (nyt afsnit III)....

  13. Forandring av selvoppfatning blant studenter i løpet av en bachelorutdanning i sykepleie

    OpenAIRE

    John Olav Bjørnestad; Anne Valen-Senstad Skisland; Olle Söderhamn

    2010-01-01

    Selvoppfatning er av betydning for faglig framgang og kreativitet. Hensikten med denne studien var å beskrive forandring av selvoppfatning hos en gruppe sykepleierstudenter i løpet av sin treårige bachelorutdanning. En studiegruppe med 127 sykepleierstudenter ved en norsk høgskole besvarte et spørreskjema i første og siste studieår. Skalaer for måling av generell selvoppfatning og regelbevissthet samt spørsmål om bakgrunnsvariabler inngikk i spørreskjemaet. Resultatene viste at selvoppfatning...

  14. Forsøk med planting av lakserogn i nedre Glomma 2011-2012

    OpenAIRE

    Rustadbakken, A.; Lund, E.

    2013-01-01

    Som avbøtende tiltak mot rekrutteringssvikt hos laks i Glomma, ble det vinteren 2011-2012 gjennomført et rognplantingsforsøk. Rogna ble plantet i Whitlock-Vibert-Bokser (WVB) for å kunne evaluere klekkesuksess på fire stasjoner. Det ble totalt satt ut 45 000 rognkorn, hvorav 10 000 stk ble satt ut i kontrollkasser for evaluering av klekkesuksess. I forbindelse med vannføringsøkning i april, mista vi to av de fire kontrollkassene. Rognoverlevelsen ved Papirfabrikken (1) og oppstrøms Grusørene ...

  15. Kaffe kan være gavnlig ved leversygdom

    DEFF Research Database (Denmark)

    Kjærgaard, Maria; Thiele, Maja; Krag, Aleksander

    2014-01-01

    Coffee is one of the most commonly consumed beverages in the world. Consequently, it is important to consider the impact of coffee on health and disease. A daily intake of at least three cups of coffee is likely to have beneficial health effects, especially in patients at risk of liver diseases....... Coffee has been associated with decreased liver inflammation, prevention of cirrhosis, reduced steatosis and lower incidence of hepatocellular carcinoma. It is not yet possible to make clear recommendations, but coffee can likely be included as part of a healthy diet for patients with liver diseases....

  16. Jernalderbebyggelsen ved Grøntoft i forskningshistorisk perspektiv

    DEFF Research Database (Denmark)

    Rindel, Per Ole

    2011-01-01

    . Placeringen midt på Skovbjerg Bakkeø, hvor hovedvandskellene mødes, kan dog have haft en særlig strategisk betydning, og ét af langhusene fra tidlig førromersk jernalder synes at repræsentere en potentiel stormandsgård. I de seneste år har bl.a. svenske arkæologer tilføjet nye aspekter til forskningen i...

  17. Laktatacidose ved behandling af type 2-diabetes med metformin

    DEFF Research Database (Denmark)

    Holst, Helle; Eldrup, Ebbe; Guldstad, Nana Harriet

    2012-01-01

    Metformin (MET) is the first-line agent in treatment of type 2 diabetes. However, MET has been associated with lactic acidosis (MALA), a potential but rare complication which has influenced treatment strategies in decades. Recently, guidelines have been changed in regards of age and heart failure...

  18. Anvendelse af monoaminooksidasehæmmeren isocarboxazid ved behandlingsresistent depression

    DEFF Research Database (Denmark)

    Larsen, Jens Knud; Krogh-Nielsen, Lene; Brøsen, Kim

    2015-01-01

    drugs. The risk of developing oedema can be reduced by vitamin B6 treatment. Normal dosage isocarboxazide may be prescribed for all patients because isocarboxazide is not metabolized through the CYP2D6 enzyme complex like most other antidepressants. It is recommended to include isocarboxazide...

  19. Otte opmærksomhedspunkter ved evaluering af politiske reformer

    DEFF Research Database (Denmark)

    Hansen, Morten Balle; Breidahl, Karen Nielsen; Furubo, Jan-Eric

    2015-01-01

    Denne artikel analyserer udfordringer knyttet til evalueringer af større politiske reformer. Den er baseret på en metaevaluering af evalueringen af NAV reformen i Norge, der både var en betydelig reorganisering af statslig, regional og kommunal forvaltning og en socialpolitisk reform. Metaevaluer...

  20. Ernæring og kosttilskud ved kronisk inflammatorisk tarmsygdom

    DEFF Research Database (Denmark)

    Hvas, Christian Lodberg; Borre, Mette; Fassov, Janne Ladefoged

    2017-01-01

    as treatment. The use of probiotics is not encouraged in patients with Crohn's disease, but it may maintain remission in ulcerative colitis. Curcumin, chamomile, and other herbal extracts are promising in the treatment of mild ulcerative colitis, but validation of products and monitoring of side effects...

  1. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    2010-01-01

    Epilepsy is a common neurological disorder, and between one fourth and one third of the patients do not obtain seizure freedom after treatment with antiepileptic drugs. If the epileptic seizures in such patients have severe consequences, the patients should be assessed for epilepsy surgery. In case...... epilepsy surgery is not feasible, vagus nerve stimulation (VNS) should be offered. VNS seems to have an effect in all epilepsy syndromes and seizure types. VNS is generally well-tolerated, and may even improve mood and quality of life. Many more epilepsy patients in Denmark should be offered VNS....

  2. Bestemmelse af døgnblodtryksvariationer ved cirrose

    DEFF Research Database (Denmark)

    Møller, S; Wiinberg, N; Henriksen, Jens Henrik Sahl

    1996-01-01

    device for monitoring blood pressure in 35 patients with cirrhosis and 35 healthy matched controls. During the day-time, SBP, DBP and MAP were significantly lower in the patients than in the controls (median 118 vs 127; 70 vs 78; 86 vs 94 mmHg, p ..., but surprisingly normal arterial blood pressure during the night-time, and the circadian variation in blood pressure and HR is diminished probably due to an almost unaltered cardiac output during the 24 hours. These results may reflect a major defect in the ability of optimal regulation of blood pressure...

  3. Kognitive forstyrrelser ved depression - betydning for behandling og prognose

    DEFF Research Database (Denmark)

    Ravnkilde, Barbara; Bruun, Louise Meldgaard; Videbech, Poul

    2007-01-01

    Depression is often accompanied by cognitive disturbances, and by focusing on these deficits practitioners can obtain important information about the status of the disease and the prognosis of the patient. From this perspective, patients may also gain useful insight into their own condition....... Medical and psychological treatment interventions can be applied on different levels particularly in relation to the cognitive symptoms of depression. Udgivelsesdato: 2007-Apr-16...

  4. Nye diagnostiske tiltag ved akantamøbekeratitis

    DEFF Research Database (Denmark)

    Nielsen, Esben Tranholm; Heegaard, Steffen; Hjortdal, Jesper Østergaard

    2011-01-01

    Acanthamoeba keratitis is a rare but sight threatening condition. A major problem is that the disease is difficult to diagnose and often mistaken for herpes infection in its early stages. We present an update in diagnostics with the presentation of five recent cases of Acanthamoeba keratitis where...

  5. Rekonvalescens efter praeoperativ fysisk traening ved elektiv kirurgi

    DEFF Research Database (Denmark)

    Kjaer, Michael; Krogsgaard, Michael R; Magnusson, Peter

    2009-01-01

    Elective surgery is associated with decreased postoperative musculoskeletal function. High aerobic capacity and muscle strength prior to operation is associated with a shorter and more uncomplicated postoperative period. Pre-operative training as intervention has only showed very limited effect...

  6. Overvej cannabinoid hyperemesis-syndrom ved recidiverende opkastninger

    DEFF Research Database (Denmark)

    Nordholm-Carstensen, Andreas

    2014-01-01

    Cannabinoid hyperemesis syndrome (CHS) is characterised by unrelenting nausea, recurrent vomiting, abdominal pain and compulsive, hot bathing behaviour. The symptoms contrast the traditional effects associated with cannabis use. We report a "textbook example" of a 26-year-old man with CHS. CHS...... is an important differential diagnosis to consider in patients with similar symptoms and the distinctive symptom relief in hot water. Early recognition may prevent extensive, unnecessary medical examinations and frequent hospital admissions....

  7. Myokardieskintigrafi. Praecis og omkostningseffektiv billeddiagnostik ved koronarsygdom--sekundaerpublikation

    DEFF Research Database (Denmark)

    Hesse, B.; Petersen, C.L.; Marcassa, C.

    2008-01-01

    Mortality rates due to coronary arterial disease (CAD) have declined as result of improved prevention, diagnosis and management, but CAD remains the leading cause of death. Myocardial perfusion scintigraphy (MPS) provides a cost-effective tool for early detection of CAD in symptomatic individuals...

  8. Strategier ved udredning af malassimilation. En kritisk status

    DEFF Research Database (Denmark)

    Rumessen, J J

    1997-01-01

    malassimilation. The frequency and clinical importance of this condition is in all probability underestimated. Screening for coeliac disease may be achieved by several serological tests (reticulin-, gliadin-, endomysial antibodies), of which IgA-endomysial antibodies seem superior. Comparative studies are often...

  9. Forekomst og behandling af seksuel dysfunktion ved hjertesygdom

    DEFF Research Database (Denmark)

    Mickley, Hans

    2002-01-01

    Several links have been established between sexual dysfunction and heart disease. Indeed, many risk factors for developing sexual dysfunction are shared by coronary artery disease: age, smoking, diabetes, hypertension, and hypercholesterolaemia. It should also be borne in mind that in men several...... cardiac drugs are responsible for erectile dysfunction (ED). Lastly it should be remembered that treatment of ED may be associated with cardiovascular side-effects. Data from the literature show that men with coronary artery disease, hypertension or diabetes have an up to fourfold higher risk...... of developing ED than have age-matched controls. Thiazide diuretics and beta-blockers are the most common drugs that produce ED. Current therapies for ED are safe and effective in the large majority of patients with cardiovascular disease. However, the concomitant use of nitrates and sildenafil may be life...

  10. Cancer kan være differentialdiagnose ved psykiatriske symptomer

    DEFF Research Database (Denmark)

    Eibye, Simone; Speyer, Helene; Benros, Michael Eriksen

    2015-01-01

    We present a patient with psychiatric symptoms as the first manifestation from an undetected brain tumor. The patient had symptoms of psychosis and a prior history with depression. A slight alteration in consciousness was found but no neurological deficits. Blood tests showed increased infection ...... of physical origin....

  11. Bestemmelse af døgnblodtryksvariationer ved cirrose

    DEFF Research Database (Denmark)

    Møller, Søren; Wiinberg, N; Henriksen, Jens Henrik

    1996-01-01

    , but surprisingly normal arterial blood pressure during the night-time, and the circadian variation in blood pressure and HR is diminished probably due to an almost unaltered cardiac output during the 24 hours. These results may reflect a major defect in the ability of optimal regulation of blood pressure......Cirrhotic patients have disturbed systemic haemodynamics with reduced arterial blood pressure, but this has not been investigated during daily activity and sleep. Systolic (SBP), diastolic (DBP), and man arterial blood pressure (MAP), and heart rate (HR) were measured by an automatic ambulatory...... device for monitoring blood pressure in 35 patients with cirrhosis and 35 healthy matched controls. During the day-time, SBP, DBP and MAP were significantly lower in the patients than in the controls (median 118 vs 127; 70 vs 78; 86 vs 94 mmHg, p blood pressures were...

  12. Sygdomsmekanismer og nye behandlingsmetoder ved migræne

    DEFF Research Database (Denmark)

    Hansen, Jakob Møller; Ashina, Messoud

    2016-01-01

    Migraine is the most prevalent disabling neurological disorder. The management of patients with migraine has been hampered by lack of effective and well-tolerated acute and preventive therapies. Based on improved insights into the basic mechanisms of migraine, new and targeted treatments are curr......Migraine is the most prevalent disabling neurological disorder. The management of patients with migraine has been hampered by lack of effective and well-tolerated acute and preventive therapies. Based on improved insights into the basic mechanisms of migraine, new and targeted treatments...... are currently undergoing large-scale testing. Among the most promising agents for migraine prevention are humanized antibodies against calcitonin gene-related peptide (CGRP) or the CGRP receptor. If proven effective, these new treatments may emerge to improve the lives of millions of individuals worldwide...

  13. Erythropoietin--en ny terapi ved cerebral iskaemi?

    DEFF Research Database (Denmark)

    Kalialis, Louise Vennegaard; Olsen, Niels Vidiendal

    2003-01-01

    administration of recombinant EPO ameliorates neuronal damage after brain ischaemia, and prevents the loss of autoregulation of cerebral blood flow following experimental subarachnoid haemorrhage. Recombinant human EPO is a safe and non-toxic drug, and clinical studies are currently investigating...... as an anti-inflammatory and neuroprotective drug. EPO and its receptor are expressed in neurons, glial cells and brain capillary endothelial cells, and the system is upregulated in conditions of cerebral ischaemia and hypoxia. Animal studies have now established that intracerebroventricular administration...... of recombinant EPO exerts neuroprotection in models of stroke. The mechanisms appear to involve an upregulation of specific anti-apoptotic and anti-inflammatory pathways. In addition, neurotrophic and angiogenetic effects of EPO may contribute in a long latency protection. Interestingly, also systemic...

  14. Selektive utfordringer ved assistert befruktning for personer med Klinefelter syndrom

    OpenAIRE

    Bjørn Hofmann

    2008-01-01

    Ny bioteknologi gir nye muligheter som har vist seg å være moralsk utfordrende. Det gjelder særlig innenfor menneskelig reproduksjon, der denne teknologien er spesielt potent. Med virkeliggjøringen av antikkens drøm om å kunne påvirke fremtidige barns egenskaper følger en rekke vanskelige valg. I analysen av og debatten om slike valg har man forsøkt å skille mellom tilvalg og fravalg med hensyn på bestemte egenskaper. Ett konkret eksempel er hvorvidt personer med Klinefelter syndrom skal tilb...

  15. Selektive utfordringer ved assistert befruktning for personer med Klinefelter syndrom

    Directory of Open Access Journals (Sweden)

    Bjørn Hofmann

    2008-05-01

    Full Text Available Ny bioteknologi gir nye muligheter som har vist seg å være moralsk utfordrende. Det gjelder særlig innenfor menneskelig reproduksjon, der denne teknologien er spesielt potent. Med virkeliggjøringen av antikkens drøm om å kunne påvirke fremtidige barns egenskaper følger en rekke vanskelige valg. I analysen av og debatten om slike valg har man forsøkt å skille mellom tilvalg og fravalg med hensyn på bestemte egenskaper. Ett konkret eksempel er hvorvidt personer med Klinefelter syndrom skal tilbys assistert befruktning, og det illustrerer at slike skiller kanskje ikke er så dekkende eller viktige for den etiske debatten som man kan få inntrykk av. Andre grunnleggende problemstillinger synes vel så påtrengende. Det betyr ikke at vi må forkaste seleksjonsmodellen. Eksemplet med Klinefelter syndrom stimulerer derimot til å revidere og utvikle den, og det gir føringer for hvordan modellen kan nyanseres og anvendes ut over skillet mellom tilvalg og fravalg. Denne revisjonen kan redusere seleksjonsproblematikkens polemiske kraft, men kanskje også øke dens anvendelse for etikk i praksis.http://dx.doi.org/10.5324/eip.v2i1.1690

  16. Postoperativ strålebehandling ved cancer mammae

    DEFF Research Database (Denmark)

    Overgaard, Marie; Kvistgaard, Marianne Ewertz; Thomsen, Mette Skovhus

    2007-01-01

    Postoperative radiotherapy (RT) is an important part of the multidisciplinary treatment of early breast cancer. Meta-analyses of large randomized trials of RT after lumpectomy and mastectomy have shown that RT reduces the risk of local recurrence with at least 70% and mortality after 15 years...

  17. Apoptose ved kronisk inflammatorisk tarmsygdom. Betydning for patogenese og behandling

    DEFF Research Database (Denmark)

    Seidelin, Jakob Benedict; Nielsen, Ole Haagen

    2003-01-01

    Inflammatory bowel disease (IBD) is characterized by the increased survival of lamina propria leucocytes and ulcerations and an increased epithelial leakiness that compromise the barrier function of the epithelial lining. Deregulated apoptosis seems to be a major cause of the impaired barrier fun...

  18. Ingeniørenes rolle ved skabelse af innovative koncepter

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2007-01-01

    mikromøller (til installering på taget derhjemme i Storbritannien) lægger alle sammen pres på den danske vindmøllebranche. Der er også en teknologipark i Spanien, hvor virksomheder som Microsoft, Hewlett Packard og General Motors forsynes med 100 procent vedvarende energi fra lokalområdet. Teknologiparken har...

  19. Værdien af arbejdstest ved akut koronart syndrom

    DEFF Research Database (Denmark)

    Mickley, H; Madsen, J K

    2001-01-01

    In general, exercise testing in acute coronary syndrome (ACS) has been used in the assessment of physical capacity and to obtain prognostic information. Within recent years, however, a number of randomized studies have addressed the role of exercise testing in identifying patients, who may benefit....... An invasive strategy is warranted in patients who continue to have angina and exhibit significant ST-segment depression in the exercise-ecg or reversible defects on perfusion scintigraphy. Based on the results of a recent, large scale randomized study, patients with unstable angina or acute non...... from an invasive versus a conservative treatment strategy. According to the literature, a normal exercise test result after ACS is associated with an excellent clinical outcome. Patients who for clinical reasons are unable to perform an exercise test comprise a high risk group for future cardiac events...

  20. Ingen registrering af komplikationer til implantater ved gynaekologiske operationer

    DEFF Research Database (Denmark)

    Sørensen, Helle Christina; Lose, Gunnar; Sander, Pia

    2010-01-01

    In recent years, many new surgical implants (biological and synthetic) for female urinary incontinence and pelvic organ prolapse (POP) surgery have been launched in Denmark. In the literature, complications have been reported in up to 40% of cases depending on the type of operation, 2-5% as serious...

  1. Også gravide skal rektaleksploreres ved anale symptomer

    DEFF Research Database (Denmark)

    Højgaard, Helle Manfeld; Rahr, Hans

    2012-01-01

    assessment. Following caesarian section, diagnostic workup showed multiple liver metastases. Rectal cancer in pregnancy is rare, while haemorrhoids are common. We recommend keeping the differential diagnoses in mind and performing a digital rectal examination if pregnant women have anal symptoms.......A case of disseminated rectal cancer in a 32-year-old pregnant woman is described. Pain was her main complaint, but this had been ascribed to haemorrhoids and treated with topical agents. She was diagnosed with rectal cancer late in the third trimester when her midwife referred her for surgical...

  2. Forebyggende ambulant behandling ved affektiv lidelse (depression og mani)

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Hansen, Hanne Vibe; Hougaard, Esben

    2007-01-01

    The present article is based on a Health Technology Assessment Report (HTA, available with an English summary at www.cemtv.dk) on preventive out-patient treatment of affective disorders. The article briefly reviews the course of depressive disorder and bipolar affective disorder and reviews the b...... the best available treatment modalities including shared care models, prophylactic pharmacotherapy and prophylactic combination therapy involving pharmacotherapy and psychological treatment....

  3. Apoptose ved kronisk inflammatorisk tarmsygdom. Betydning for patogenese og behandling

    DEFF Research Database (Denmark)

    Seidelin, Jakob Benedict; Nielsen, Ole Haagen

    2003-01-01

    Inflammatory bowel disease (IBD) is characterized by the increased survival of lamina propria leucocytes and ulcerations and an increased epithelial leakiness that compromise the barrier function of the epithelial lining. Deregulated apoptosis seems to be a major cause of the impaired barrier...

  4. Nye behandlingsmuligheder ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathog...

  5. Patofysiologien ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune-mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved...

  6. Atypisk manifestation ved infektiøs endokarditis

    DEFF Research Database (Denmark)

    Pareek, Manan; Hansen, Lars Koch; Rujic, Dragana

    2013-01-01

    Infective endocarditis is a serious disease associated with a high mortality. The initial presentation may be non-specific and misleading, thus delaying correct diagnosis. In this case report, we describe a 46-year-old woman, who presented with symptoms suggestive of systemic lupus erythematosus,......, including malar rash, arthritis, acute renal failure and thrombocytopenia, but she was subsequently proven to have infective endocarditis involving the mitral valve. Her rheumatological symptoms diminished after antibiotic therapy and mitral valve surgery....

  7. Nye behandlingsmuligheder ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved...

  8. Optagelsessamtaler på medicin-studiet ved Aarhus Universitet

    DEFF Research Database (Denmark)

    Andreassen, Pernille; Pedersen, Kamilla; Jensen, Rune Dall

    I denne rapport præsenteres evalueringsresultaterne af en pilottest af et optagelsessamtale-format, som fra foråret 2016 vil være en del af kvote 2 optagelsesproceduren til medicinstudiet på Aarhus Universitet (AU). Multiple Mini Interview (MMI) er et optagelsessamtale-format, som bruges til at t...

  9. sikkerhedskultur som centralt middel ved forebyggelsen af arbejdsulykker

    DEFF Research Database (Denmark)

    Dyhrberg, Mette Bang

    1999-01-01

    Artiklen præsenterer tre faser i den internationale forskning omkring arbejdsulykker. I den første fase handler forebyggelsen om at gøre maskinerne mere sikre, i den anden fase fokuseres på person udvælgelse og teknisk risikovurdering, mens der i den sidste fase inddrages organisatoriske forhold ...

  10. Laparoskopisk eller åben subtotal kolektomi ved inflammatorisk tarmsygdom

    DEFF Research Database (Denmark)

    Lindberg, Lars Joachim; Rosenberg, Jacob; Achiam, Michael Patrick

    2010-01-01

    Studies have shown that laparoscopic colectomy (LC) for inflammatory bowel disease (IBD) is just as safe as open colectomy. Some of the short-term advantages of laparoscopy are faster recovery, less pain, shorter hospital stay and fewer complications. The long-term advantages include superior cos...... cosmetic result, reduced intra abdominal adhesion formation, less frequent hospitalization due to small bowel obstruction and fewer incisional hernias. Cost-benefit analyses also favour laparoscopic surgery for IBD....

  11. Marin recipientundersøgelse ved Thule Air Base 2002

    DEFF Research Database (Denmark)

    Glahder, C. M.; Asmund, G.; Mayer, P.

    I 2002 gennemførte Danmarks Miljøundersøgelser en recipientundersøgelse ud for Thule Air Base (TAB) for at vurdere, om aktiviteterne og specielt de efterladte dumpe på TAB har belastet det marine miljø med forurenende stoffer. Undersøgelsen viser, at der findes flere forurenings-kilder som f. eks...

  12. Ingen registrering af komplikationer til implantater ved gynaekologiske operationer

    DEFF Research Database (Denmark)

    Sørensen, Helle Christina; Lose, Gunnar; Sander, Pia

    2010-01-01

    In recent years, many new surgical implants (biological and synthetic) for female urinary incontinence and pelvic organ prolapse (POP) surgery have been launched in Denmark. In the literature, complications have been reported in up to 40% of cases depending on the type of operation, 2-5% as serio...... complications. An implant can achieve CE-marking if it seems likely that it is substantially equivalent to an implant already on the market. Thus implants can be launched without clinical data....

  13. Danger-signaler og inflammasomer ved autoinflammatoriske og autoimmune sygdomme

    DEFF Research Database (Denmark)

    Bendtzen, Klaus

    2011-01-01

    Cytoplasmic inflammasomes are formed through activation of pattern recognition receptors (PRR) of the innate immune system. Endogenous and exogenous danger signals, e.g. DNA- and RNA-fragments, urate- and cholesterol crystals, silica and asbestos, ß-amyloid, UV-light and skin irritants, may induce...

  14. Danskernes seksualliv belyst ved befolkningsundersøgelser

    DEFF Research Database (Denmark)

    Eplov, Lene Falgaard; Garde, Karin; Køster, Anne

    2002-01-01

    The sexual life is multitudinous and sexual dysfunctions should be interpreted in this complexity. Broader descriptive sexological studies based on normal populations are thus of relevance in medical science. The aim of this review was to describe existing Danish studies on sexuality in normal po...

  15. Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Djurhuus, Sissal Sigmundsdóttir; Brasso, Klaus; Berg, Kasper Drimer

    2015-01-01

    Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective...... drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management....

  16. Praediktorer for kroniske følger ved whiplashtraume

    DEFF Research Database (Denmark)

    Kasch, Helge; Kongsted, Alice; Carstensen, Tina Birgitte

    2010-01-01

    Prognostic factors for chronic whiplash-associated disorder (WAD) are identified. In WAD grade I-III, 50% report neck pain after one year (30% in background population). There is a female preponderance among WAD cases. 10% develop a work disability, but no gender differences are found. Age, crash...... issues, magnetic resonance imaging of the neck and smooth-pursuit-neck-torsion-test are of no prognostic value. While reduced active neck mobility is associated with a 4.6 times raised risk for work disability after one year, the impact-of-event score yielded an increase in OR of 3.3, and intense pre...

  17. Manglende effekt af substitutionsbehandling ved alfa 1-antitrypsin-mangel

    DEFF Research Database (Denmark)

    Dahl, Ronald; Hilberg, Ole; Ottesen, Anders Løkke

    2011-01-01

    Persons with alpha1-antitrypsin (A1AT) deficiency and chronic obstructive pulmonary disease (COPD) have been tested for the clinical value of regular intravenous infusion with A1AT in two small double-blind randomised controlled trials. The trials found a statistical significant reduction in the ...

  18. Infektionsfare ved indtagelse af ubehandlet rå fisk

    DEFF Research Database (Denmark)

    Buchmann, Kurt

    2007-01-01

    Der gives en gennemgang af nogle de typer parasitter, som kan forefindes i fiskekød. Desuden fortællles om hvorledes de pågældende orme kan inficere mennesker, hvis kødet indtages råt. Forebyggende tiltag beskrives. Udgivelsesdato: 20. april......Der gives en gennemgang af nogle de typer parasitter, som kan forefindes i fiskekød. Desuden fortællles om hvorledes de pågældende orme kan inficere mennesker, hvis kødet indtages råt. Forebyggende tiltag beskrives. Udgivelsesdato: 20. april...

  19. Cerebral sinustrombose ved Behçets sygdom

    DEFF Research Database (Denmark)

    Schytz, Henrik Winther; Wegener, Marianne; Lassen, Lisbeth Landschoff

    2012-01-01

    Behçet's disease (BD) is a chronic relapsing inflammatory disorder of unknown aetiology with involvement of multiple organs. The incidence of BD is highest in the countries along the ancient Silk Route. In approximately 9% of the BD patients there is involvement of the central nervous system (CNS...... with CNS affection is an important diagnosis to keep in mind in case of cerebral venous thrombosis....

  20. Magnetisk resonans ved haematologiske sygdomme. Billeddannelse af knoglemarven

    DEFF Research Database (Denmark)

    Jensen, K E

    1995-01-01

    Magnetic resonance imaging (MRI) is a highly sensitive alternative to plain radiography, CT, and radionuclide studies for the imaging of normal and abnormal bone marrow. The cellularity and the corresponding fat/water ratio within the bone marrow show clear changes in haematological diseases....... This enables MRI to detect differences between fatty, fibrotic, aplastic and hypercellular marrow in patients with haematological disease. MRI can evaluate the distribution of bone marrow disease because it has the potential for visualization of almost the entire bone marrow compartment. However, MRI is unable...... to establish the primary diagnosis in haematological bone marrow disease with diffuse hypercellular marrow. In case of insufficient biopsy, MRI can provide important differential diagnostic information as well as guidance for further biopsy attempts. MRI is a useful complement to morphological bone marrow...