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  1. The aluminium content of infant formulas remains too high.

    Science.gov (United States)

    Chuchu, Nancy; Patel, Bhavini; Sebastian, Blaise; Exley, Christopher

    2013-10-08

    Recent research published in this journal highlighted the issue of the high content of aluminium in infant formulas. The expectation was that the findings would serve as a catalyst for manufacturers to address a significant problem of these, often necessary, components of infant nutrition. It is critically important that parents and other users have confidence in the safety of infant formulas and that they have reliable information to use in choosing a product with a lower content of aluminium. Herein, we have significantly extended the scope of the previous research and the aluminium content of 30 of the most widely available and often used infant formulas has been measured. Both ready-to-drink milks and milk powders were subjected to microwave digestion in the presence of 15.8 M HNO3 and 30% w/v H2O2 and the aluminium content of the digests was measured by TH GFAAS. Both ready-to-drink milks and milk powders were contaminated with aluminium. The concentration of aluminium across all milk products ranged from ca 100 to 430 μg/L. The concentration of aluminium in two soya-based milk products was 656 and 756 μg/L. The intake of aluminium from non-soya-based infant formulas varied from ca 100 to 300 μg per day. For soya-based milks it could be as high as 700 μg per day. All 30 infant formulas were contaminated with aluminium. There was no clear evidence that subsequent to the problem of aluminium being highlighted in a previous publication in this journal that contamination had been addressed and reduced. It is the opinion of the authors that regulatory and other non-voluntary methods are now required to reduce the aluminium content of infant formulas and thereby protect infants from chronic exposure to dietary aluminium.

  2. Description of plastic remains found in the stomach contents of the jumbo squid Dosidicus gigas landed in Ecuador during 2014.

    Science.gov (United States)

    Rosas-Luis, Rigoberto

    2016-12-15

    Squids are active and opportunistic predators that feed on a wide range of prey. Their active movements in the water column and their voracity promote a high consumption of food. In the pelagic environment off Ecuador, marine pollution is characterized by plastic debris with a mainland origin, including plastics trash of fishing gears. The objective of this work was to describe the presence of plastic remains in the stomach contents of Dosidicus gigas caught off the coast of Ecuador. Results demonstrated that 12% of the stomachs contained plastic remains. These plastics were identified as multifilament of polyethylene lines and polyvinyl chloride remains. Findings of this work could be related to an increase in the discharge of solid materials in the water column, increasing the probability to be ingested by the jumbo squid. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Long-Term Efficacy, Tolerability, and Renal Safety of Atazanavir/Ritonavir-based Antiretroviral Therapy in a Cohort of Treatment-Naïve Patients with HIV-1 Infection: the REMAIN Study.

    Science.gov (United States)

    Teófilo, Eugénio; Rocha-Pereira, Nuno; Kuhlmann, Birger; Antela, Antonio; Knechten, Heribert; Santos, Jesús; Jiménez-Expósito, Maria Jesús

    2016-02-01

    Boosted protease inhibitors (PIs), including ritonavir-boosted atazanavir (ATV/r), are a recommended option for the initial treatment of HIV-1 infection based upon clinical trial data; however, long-term real-life clinical data are limited. We evaluated the long-term use of ATV/r as a component of antiretroviral combination therapy in the real-life setting in the REMAIN study. This was an observational cohort study conducted at sites across Germany, Portugal, and Spain. Retrospective historical and prospective longitudinal follow-up data were extracted every six months from medical records of HIV-infected treatment-naïve patients aged ≥ 18 years initiating a first-line ATV/r-containing regimen. Eligible patients (n = 517) were followed up for a median of 3.4 years. The proportion remaining on ATV/r at 5 years was 51.5% with an estimated Kaplan-Meier median time to treatment discontinuation of 4.9 years. Principal reasons for discontinuation were adverse events (15.9%; 8.9% due to hyperbilirubinemia) and virologic failure (6.8%). The Kaplan-Meier probability of not having virologic failure (HIV-1 RNA treatment-emergent major PI resistance occurred. ATV/r was generally well tolerated during long-term treatment with no significant changes in estimated glomerular filtration rate over five years. In a real-life clinical setting over five years, treatment-naïve patients with HIV-1 infection initiating an ATV/r-based regimen showed sustained virologic suppression, an overall treatment persistence rate of 51.5%, an absence of treatment-emergent major PI resistance mutations at virologic failure, a long-term safety profile consistent with that observed in clinical trials, and no significant decline in renal function.

  4. A WELL PRESERVED SKELETON OF THE FOSSIL SHARK COSMOPOLITODUS HASTALIS FROM THE LATE MIOCENE OF PERU, FEATURING FISH REMAINS AS FOSSILIZED STOMACH CONTENTS

    Directory of Open Access Journals (Sweden)

    ALBERTO COLLARETA

    2017-01-01

    Full Text Available Both the preservation of the poorly mineralized skeleton of sharks and the preservation of stomach contents are rarely observed in the fossil record. Here we report on a partial skeleton of a lamniform shark, including portions of the visceral arches and the anterior segment of the vertebral column, collected from the late Miocene beds of the Pisco Formation exposed at Cerro Yesera (Ica Desert, South Peru. Based on the morphology of the preserved teeth, this specimen was determined as a juvenile of the extinct lamnid species Cosmopolitodus hastalis. The shark skeleton includes remains of fish (featuring a pilchard determined as Sardinops sp. cf. S. sagax in the abdominal region. These fish remains are interpreted herein as the fossilized stomach contents of the shark. For the first time, piscivory is demonstrated in a juvenile individual of Cosmopolitodus hastalis. This result is consistent with the current knowledge about the feeding habits of immature individuals of extant lamniform shark species (including Carcharodon carcharias and Isurus oxyrinchus. Our report further outlines the fundamental role of schooling pilchards in the late Miocene trophic chains of the highly productive coastal waters off present South Peru. Moreover, the find of this well preserved shark skeleton strengthens the qualification of the Pisco Formation as a Fossil-Lagerstätte, and emphasizes the role of early mineralization processes in cases of exceptional preservation.

  5. Ethical Disputes and Credibility of Daily Newspapers-Content Analysis of Front Page Newspaper Articles in Jutarnji list and Večernji list

    Directory of Open Access Journals (Sweden)

    Dunja Majstorović

    2010-12-01

    Full Text Available Among the more common assertions regarding the media is the existence of a large number of ethical disputes in front page news articles in daily newspapers. Therefore, the main goal of this studyis to establish the number of ethical disputes in articles placed on the front pages of Croatia’s two main dailies, Jutarnji list and Večernji list (sample of one month. In the course of the research three hypotheses were made with the purpose of verifying their accuracy. Using content analysis as the primary method for analysis, the ethically disputable articles were divided into the following categories: anonymous sources, biased display of events, violations of human rights, inappropriate reporting, and headlines that fail to match the text. The same articles were then classifi ed into categories according to their topics. The results of this study confi rm all three hypotheses, the fi rst of which is that there are a large number of ethical disputes in the analyzed articles. In Jutarnji list 26 articles (of 95 analyzed articles contained 30 ethical disputes and in Večernji list 23 articles (of 108 analyzed contained 29 ethical disputes. Further, this study concludes that there is a distinct similarity in the number of ethical disputes in the articles in both newspapers. The results verify the third hypothesis; the largest number of ethically disputable articles centered on topics related to domestic politics. The results of the research indicate a violation of journalism ethics which can be explained by increasing sensationalism in daily newspapers. The result of inappropriate reporting has a significant impact on the decline of credibility of newspapers as a medium.

  6. VE of construction industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-10-15

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  7. VE of construction industry

    International Nuclear Information System (INIS)

    1987-10-01

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  8. Bakü İçeri Şeher’de Selçuklular Döneminden Kalma İki Mescit: Sınıg Gala (Muhammed (1078 Ve Aşur (1169 Mescitleri (Two Masjid Around Baku İçeri Şeher Remaining From Seljuks: Sinig Gala (Muhammed (1078 And Ashur (1169 Masjids

    Directory of Open Access Journals (Sweden)

    Ramazan UYKUR

    2012-12-01

    Full Text Available Today, there are a great many of small scaled masjıds in oldBaku, which is called today İçeri Şeher (The Inland City. In this paper,the earliest two cultural material samples of Seljuks in Azerbajcan aswell as Anatolia are depicted. In the study, the main aim is theinvestigation of these two works, which are little known in Turkishworld, in some points of view such as their history, contractors,designs, architectures and ornament. For this reason, in a number ofbuildings in Bakuand around it, some procedures were performed suchas required measures, technical drawings, and photographing. Afterthat, the study was completed with source inquiries in the Archives ofBaku Berpa, Ahundov Library along with a number of Turkish libaries.Consequently, in their new homelands too, Turks tended to apply theaesthetical values, architectural approach and artistic motives whichthey brought in their mind togetheras well as remarkable politicalachievements which they obtained by housing Anatolia. Therefore, it ishighly probable to come accross such samples of pre-Anatolian culturalheritage in the cities they built or on the routes they passed throughduring this mobility.Both of the buildings are considered remarkable in that they arethe earliest samples from Seljuks which have remained until today,making it available us to track down the developments in Turkisharchitecture. Sınıg Gala Masjid, the first small built after Turks' arrivingin Baku, is still found remarkable since it has statical problems as wellas its slipshod appearance and its huge minarets that is independentlybuilt from the main building. As for the Ashur Masjids, with its twostorey facade and embellished supporting arch seperating the inside, itis undoubtedly a work of a less-developed architectural styleestablishment of the period. However, the most considerable drawbackin both of the vaulted buildings is the practise of gloomy, dim andfailedlocations. As a result, even though they are

  9. Functional Analysis of the Tomato Immune Receptor Ve1 through Domain Swaps with Its Non-Functional Homolog Ve2

    Science.gov (United States)

    Rovenich, Hanna; Song, Yin; Liebrand, Thomas W. H.; Masini, Laura; van den Berg, Grardy C. M.; Joosten, Matthieu H. A. J.; Thomma, Bart P. H. J.

    2014-01-01

    Resistance in tomato against race 1 strains of the fungal vascular wilt pathogens Verticillium dahliae and V. albo-atrum is mediated by the Ve locus. This locus comprises two closely linked inversely oriented genes, Ve1 and Ve2, which encode cell surface receptors of the extracellular leucine-rich repeat receptor-like protein (eLRR-RLP) type. While Ve1 mediates Verticillium resistance through monitoring the presence of the recently identified V. dahliae Ave1 effector, no functionality for Ve2 has been demonstrated in tomato. Ve1 and Ve2 contain 37 eLRRs and share 84% amino acid identity, facilitating investigation of Ve protein functionality through domain swapping. In this study it is shown that Ve chimeras in which the first thirty eLRRs of Ve1 were replaced by those of Ve2 remain able to induce HR and activate Verticillium resistance, and that deletion of these thirty eLRRs from Ve1 resulted in loss of functionality. Also the region between eLRR30 and eLRR35 is required for Ve1-mediated resistance, and cannot be replaced by the region between eLRR30 and eLRR35 of Ve2. We furthermore show that the cytoplasmic tail of Ve1 is required for functionality, as truncation of this tail results in loss of functionality. Moreover, the C-terminus of Ve2 fails to activate immune signaling as chimeras containing the C-terminus of Ve2 do not provide Verticillium resistance. Furthermore, Ve1 was found to interact through its C-terminus with the eLRR-containing receptor-like kinase (eLRR-RLK) interactor SOBIR1 that was recently identified as an interactor of eLRR-RLP (immune) receptors. Intriguingly, also Ve2 was found to interact with SOBIR1. PMID:24505431

  10. Content

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    secondary levels. In subject matter didactics, the question of content is more developed, but it is still mostly confined to teaching on lower levels. As for higher education didactics, discussions on selection of content are almost non-existent on the programmatic level. Nevertheless, teachers are forced...... curriculum, in higher education, and to generate analytical categories and criteria for selection of content, which can be used for systematic didactical reflection. The larger project also concerns reflection on and clarification of the concept of content, including the relation between content at the level......Aim, content and methods are fundamental categories of both theoretical and practical general didactics. A quick glance in recent pedagogical literature on higher education, however, reveals a strong preoccupation with methods, i.e. how teaching should be organized socially (Biggs & Tang, 2007...

  11. Production process of VE

    International Nuclear Information System (INIS)

    1987-07-01

    This book tells of synopsis of production process of VE(value engineering), object selection method and establishment of target, collection of object information, design of function, write improvement suggestion, evaluation of improvement suggestion, all sorts of worksheets of production process of VE, explanation of IE, explanation of PERT.

  12. Kayalarda Delme ve Patlama

    OpenAIRE

    ÖZDOĞAN, Metin

    1986-01-01

    Bu makalede açık işletmecilikte delme ve patlatma işlemlerinin günümüzdeki kuramsal ve pratik durumu sunulmaktadır. Kayanın mekanik olarak parçalanması bölümünde vurmalı ve dönmeli delme dizgeleri verilmiştir. Kayanın devinik olarak parçalanması başlığı altında ise patlatma incelenmiş ve patlatma işlemini etkileyen etmenler, patlatma kuşakları, yansıma kuramı, krater deneylerine değinilmiştir

  13. The VE/CAD synergism

    International Nuclear Information System (INIS)

    Sperling, R.B.

    1993-01-01

    Value Engineering (VE) and Computer-Aided Design (CAD) can be used synergistically to reduce costs and improve facilities designs. The cost and schedule impacts of implementing alternative design ideas developed by VE teams can be greatly reduced when the drawings have been produced with interactive CAD systems. To better understand the interrelationship between VE and CAD, the fundamentals of the VE process are explained; and example of a VE proposal is described and the way CAD drawings facilitated its implementation is illustrated

  14. Contents

    Directory of Open Access Journals (Sweden)

    Editor IJRED

    2012-11-01

    Full Text Available International Journal of Renewable Energy Development www.ijred.com Volume 1             Number 3            October 2012                ISSN 2252- 4940   CONTENTS OF ARTICLES page Design and Economic Analysis of a Photovoltaic System: A Case Study 65-73 C.O.C. Oko , E.O. Diemuodeke, N.F. Omunakwe, and E. Nnamdi     Development of Formaldehyde Adsorption using Modified Activated Carbon – A Review 75-80 W.D.P Rengga , M. Sudibandriyo and M. Nasikin     Process Optimization for Ethyl Ester Production in Fixed Bed Reactor Using Calcium Oxide Impregnated Palm Shell Activated Carbon (CaO/PSAC 81-86 A. Buasri , B. Ksapabutr, M. Panapoy and N. Chaiyut     Wind Resource Assessment in Abadan Airport in Iran 87-97 Mojtaba Nedaei       The Energy Processing by Power Electronics and its Impact on Power Quality 99-105 J. E. Rocha and B. W. D. C. Sanchez       First Aspect of Conventional Power System Assessment for High Wind Power Plants Penetration 107-113 A. Merzic , M. Music, and M. Rascic   Experimental Study on the Production of Karanja Oil Methyl Ester and Its Effect on Diesel Engine 115-122 N. Shrivastava,  , S.N. Varma and M. Pandey  

  15. [PALEOPATHOLOGY OF HUMAN REMAINS].

    Science.gov (United States)

    Minozzi, Simona; Fornaciari, Gino

    2015-01-01

    Many diseases induce alterations in the human skeleton, leaving traces of their presence in ancient remains. Paleopathological examination of human remains not only allows the study of the history and evolution of the disease, but also the reconstruction of health conditions in the past populations. This paper describes the most interesting diseases observed in skeletal samples from the Roman Imperial Age necropoles found in urban and suburban areas of Rome during archaeological excavations in the last decades. The diseases observed were grouped into the following categories: articular diseases, traumas, infections, metabolic or nutritional diseases, congenital diseases and tumours, and some examples are reported for each group. Although extensive epidemiological investigation in ancient skeletal records is impossible, the palaeopathological study allowed to highlight the spread of numerous illnesses, many of which can be related to the life and health conditions of the Roman population.

  16. VE for innovative cost reduction

    International Nuclear Information System (INIS)

    1987-07-01

    This book deals with goal of value engineering characteristic of development details and development background of VE, the reason that VE is well appreciated, steps of VE process such as collection of basic information, selection of theme, organization of optimum team, item plan, function design, estimation and explanation of search result of values, item design, practical plan of innovative issue, VE reference data, and development of creative power.

  17. Content and Form Anaysis of the Web Sites of University Libraries: A study on the Case in Turkey Üniversite Kütüphaleri Web Sitelerinin Biçim ve İçerik Analizi: Türkiye'deki Uygulamaya İlişkin Bir Araştırma

    Directory of Open Access Journals (Sweden)

    Mesut Kurulgan

    2006-06-01

    Full Text Available Internet is an important medium in the process of development of information and information technologies. University library web sites are used by many users to reach information. The speed, ease and efficiency of library web site usage contributes to users' satisfaction. This study compares library web sites of state universities to the foundation universities in terms of form and content. Evaluation criteria obtained through content analysis is measured by visiting each library Web site and measures are given as frequency distribution and percentage analysis. The study concludes that library web sites of state universities use the Internet opportunities more effectively than the library web sites of foundation universities. Dünyadaki bilgi miktarının giderek artması ve bilgi teknolojilerinin gelişmesi sürecinde Internet önemli bir mecra oluşturmaktadır. Üniversite kütüphanelerinin web siteleri birçok kullanıcının bilgiye ulaşma noktasındaki beklentilerini karşılamaktadır. Kullanıcıların kütüphane web sitelerinden kolay ve etkin olarak yararlanması kullanıcı tatminini etkilemektedir. Bu çalışmada, Türkiye'deki devlet ve vakıf üniversitelerinin kütüphanelerinin web sitelerinin özellikleri, biçim ve içerik açısından karşılaştırılmaktadır. Üniversite kütüphanelerine ait web sitelerinin her bir ayrı ayrı ziyaret edilmiş ve belirlenen bazı değerlendirme ölçütleri kullanılarak içerik analizi yöntemi ile incelenmiştir. Çalışmada devlet üniversitelerinin kütüphanelerinin web sitelerinin, vakıf üniversitelerinin kütüphanelerinin web sitelerine göre daha yetkin olduğu ve Internet olanaklarını daha iyi kullandıkları belirlenmiştir.

  18. Analysis of arsenic and mercury content in human remains of the 16th and 17th centuries from Moscow Kremlin necropolises by neutron activation analysis at the IREN facility and the IBR-2 reactor FLNP JINR

    Science.gov (United States)

    Panova, T. D.; Dmitriev, A. Yu.; Borzakov, S. B.; Hramco, C.

    2018-01-01

    A neutron activation analysis (NAA) of three samples of human remains of the 16th and 17th centuries from the necropolises of the Moscow Kremlin has been carried out at FLNP JINR. The samples were irradiated at two facilities: the IREN source of resonance neutrons and the IBR-2 reactor. Spectra of the induced activity of the irradiated samples were measured by using the automatic measurement system developed at the Frank Laboratory of Neutron Physics (FLNP) of the Joint Institute for Nuclear Research (JINR). This system consists of a high-purity germanium detector with spectrometric electronics, a sample changer, and control software. Mass fraction of arsenic, mercury, and some other elements were calculated using two NAA methods—relative and absolute. The obtained values confirm the fact of acute mercury poisoning of Anastasia Romanovna, the first wife of Tsar Ivan Vasil'evich the Terrible, the first Russian Tsarina (died in 1560). High levels of mercury were detected in the bone remains of Tsarevich Ivan Ivanovich (died in 1581), the son of Tsar Ivan the Terrible, and Prince Mikhail Vasil'evich Skopin-Shuiskii (died in 1610). The results provide an opportunity to introduce into scientific circulation the exact values of mass fraction of mercury, arsenic, and other elements in the samples taken from the burials of the Russian historical figures of the second half of 16th-early 17th century.

  19. 2011 Yılı Yönetici Atama ve Yer Değiştirme Yönetmeği’nin İçeriğine ve Puanlama Ölçütlerine İlişkin Yönetici Görüşlerinin İncelenmesi Investigation of Manager Opinions on the Content and Scoring Criteria of the 2011 Manager Appointment and Rotation Regulations

    Directory of Open Access Journals (Sweden)

    Selçuk Beşir DEMİR

    2013-07-01

    Full Text Available Purpose: This study aims at determining the opinions of managersrelating to the Manager Appointment and Rotation Regulations dated2011, the scoring criteria included in the regulations and the troublesexperienced throughout the implementation process of the regulations.Method: In this research, a qualitative approach was adopted sothat the issue can be examined thoroughly. In this research, thephenomenological pattern was employed. In the research, participantswere determined by way of sampling for maximum diversity-one of theintentional sampling methods. The study group of the research consistsof 8 managers holding Office in the city X (pseudonym. Terms of Officeof the participants varies between 25 and 8 years. Semi-structuredinterview form was used as data collection tools in the research. All theinterviews were recorded on a tape recorder throughout the research. A240-minute interview was had within the scope of the research; the taperecording was computerized through the Microsoft Word processingprogram as raw data without being subjected to any screening.Line by line analysis described by Patton, (2002 was employed todescribe opinions expressed clearly and directly or implied in anindirect manner by the participants on the aim of the study withoutmanipulating them. Inductive descriptive analysis, content analysis andthe constant comparison technique was used in the interpretation ofthe interview data. The descriptive analysis project is made up of fourmain stages, namely, building up the thematic framework, processingdata according to the thematic framework, identifying the findings andinterpreting the findings.During content analysis, on the other hand, the data was dividedinto parts first and then these parts were investigated and compared.Later, meaningful concepts were built from these parts and the codesevoking the same concepts were grouped under a joint category. In thefinal stage, content integrity was derived from the themes

  20. PREPD O and VE remote handling system

    International Nuclear Information System (INIS)

    Theil, T.N.

    1985-01-01

    The Process Experimental Pilot Plant (PREPP) at the Idaho National Engineering Laboratory is designed for volume reduction and packaging of transuranic (TRU) waste. The PREPP opening and verification enclosure (O and VE) remote handling system, within that facility, is designed to provide examination of the contents of various TRU waste storage containers. This remote handling system will provide the means of performing a hazardous operation that is currently performed manually. The TeleRobot to be used in this system is a concept that will incorporate and develop man in the loop operation (manual mode), standardized automatic sequencing of end effector tools, increased payload and reach over currently available computer-controlled robots, and remote handling of a hazardous waste operation. The system is designed within limited space constraints and an operation that was originally planned, and is currently being manually performed at other plants. The PREPP O and VE remote handling system design incorporates advancing technology to improve the working environment in the nuclear field

  1. The Ve-mediated resistance response of the tomato to Verticillium dahliae involves H2O2, peroxidase and lignins and drives PAL gene expression

    Directory of Open Access Journals (Sweden)

    Merino Fuencisla

    2010-10-01

    Full Text Available Abstract Background Verticillium dahliae is a fungal pathogen that infects a wide range of hosts. The only known genes for resistance to Verticillium in the Solanaceae are found in the tomato (Solanum lycopersicum Ve locus, formed by two linked genes, Ve1 and Ve2. To characterize the resistance response mediated by the tomato Ve gene, we inoculated two nearly isogenic tomato lines, LA3030 (ve/ve and LA3038 (Ve/Ve, with V. dahliae. Results We found induction of H2O2 production in roots of inoculated plants, followed by an increase in peroxidase activity only in roots of inoculated resistant plants. Phenylalanine-ammonia lyase (PAL activity was also increased in resistant roots 2 hours after inoculation, while induction of PAL activity in susceptible roots was not seen until 48 hours after inoculation. Phenylpropanoid metabolism was also affected, with increases in ferulic acid, p-coumaric acid, vanillin and p-hydroxybenzaldehyde contents in resistant roots after inoculation. Six tomato PAL cDNA sequences (PAL1 - PAL6 were found in the SolGenes tomato EST database. RT-PCR analysis showed that these genes were expressed in all organs of the plant, albeit at different levels. Real-time RT-PCR indicated distinct patterns of expression of the different PAL genes in V. dahliae-inoculated roots. Phylogenetic analysis of 48 partial PAL cDNAs corresponding to 19 plant species grouped angiosperm PAL sequences into four clusters, suggesting functional differences among the six tomato genes, with PAL2 and PAL6 presumably involved in lignification, and the remaining PAL genes implicated in other biological processes. An increase in the synthesis of lignins was found 16 and 28 days after inoculation in both lines; this increase was greater and faster to develop in the resistant line. In both resistant and susceptible inoculated plants, an increase in the ratio of guaiacyl/syringyl units was detected 16 days after inoculation, resulting from the lowered amount

  2. VeSMEL: A Novel Approach for Distance Management of E-Learning Platforms

    Directory of Open Access Journals (Sweden)

    Bernabe Batchakui

    2011-05-01

    Full Text Available This article presents a novel approach for distance management for e-learning platforms based on VeSMp protocol. VeSMEL results from the integration of VeSMp to xMoodle 2.0 platform that has been developed. It offers a compromise between the mobility of actors and the availability of xMoodle 2.0 content in zones where internet is inaccessible. The GSM system is used like support for communication allowing the actors to reach servers from their cell phone.

  3. Türk Savunma Sanayi Firmaları Vizyon ve Misyon İfadelerinin İçerik Analizi (The Content Analysis of Vision and Mission Statements in Turkish Defense Industry Firms

    Directory of Open Access Journals (Sweden)

    Metin OCAK

    2016-08-01

    Full Text Available In this research, components used in mission and vision statements by Turkish Defense Industry Firms and their relations with national defense industry guidance documents are examined. For this reason 87 vision and 79 mission statements which mentioned on the web pages of 148 Turkish Defense Industry Firms’ are taken into consideration. A qualitative research design phenomenology was used and the data were analyzed through content analysis in this study. At the end of the analysis, it is identified that there are common 14 components in vision statements and 13 common components in mission statements. Also it is discovered that some of the components are relevant with components mentioned in the national defense industry guidance documents.

  4. And the Dead Remain Behind

    Directory of Open Access Journals (Sweden)

    Peter Read

    2013-08-01

    Full Text Available In most cultures the dead and their living relatives are held in a dialogic relationship. The dead have made it clear, while living, what they expect from their descendants. The living, for their part, wish to honour the tombs of their ancestors; at the least, to keep the graves of the recent dead from disrepair. Despite the strictures, the living can fail their responsibilities, for example, by migration to foreign countries. The peripatetic Chinese are one of the few cultures able to overcome the dilemma of the wanderer or the exile. With the help of a priest, an Australian Chinese migrant may summon the soul of an ancestor from an Asian grave to a Melbourne temple, where the spirit, though removed from its earthly vessel, will rest and remain at peace. Amongst cultures in which such practices are not culturally appropriate, to fail to honour the family dead can be exquisitely painful. Violence is the cause of most failure.

  5. The CEVALE2VE case

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00237353; The ATLAS collaboration

    2017-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in High Energy Physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, w...

  6. The CEVALE2VE case

    CERN Document Server

    Sanchez Pineda, Arturo; The ATLAS collaboration

    2016-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in high energy physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, wh...

  7. Red Assembly: the work remains

    Directory of Open Access Journals (Sweden)

    Leslie Witz

    installed. What to do at this limit, at the transgressive encounter between saying yes and no to history, remains the challenge. It is the very challenge of what insistently remains.

  8. Green business will remain green

    International Nuclear Information System (INIS)

    Marcan, P.

    2008-01-01

    It all started with two words. Climate change. The carbon dioxide trading scheme, which was the politicians' idea on solving the number one global problem, followed. Four years ago, when the project was begun, there was no data for project initiation. Quotas for polluters mainly from energy production and other energy demanding industries were distributed based on spreadsheets, maximum output and expected future development of economies. Slovak companies have had a chance to profit from these arrangements since 2005. Many of them took advantage of the situation and turned the excessive quotas into an extraordinary profit which often reached hundreds of million Sk. The fact that the price of free quotas offered for sale dropped basically to 0 in 2006 only proved that the initial distribution was too generous. And the market reacted to the first official measurements of emissions. Slovak companies also contributed to this development. However, when planning the maximum emission volumes for 2008-2012 period, in spite of the fact that actual data were available, their expectations were not realistic. A glance at the figures in the proposal of the Ministry of Environment is sufficient to realize that there will be no major change in the future. And so for many Slovak companies business with a green future will remain green for the next five years. The state decided to give to selected companies even more free space as far as emissions are concerned. The most privileged companies can expect quotas increased by tens of percent. (author)

  9. Silicon photonics: some remaining challenges

    Science.gov (United States)

    Reed, G. T.; Topley, R.; Khokhar, A. Z.; Thompson, D. J.; Stanković, S.; Reynolds, S.; Chen, X.; Soper, N.; Mitchell, C. J.; Hu, Y.; Shen, L.; Martinez-Jimenez, G.; Healy, N.; Mailis, S.; Peacock, A. C.; Nedeljkovic, M.; Gardes, F. Y.; Soler Penades, J.; Alonso-Ramos, C.; Ortega-Monux, A.; Wanguemert-Perez, G.; Molina-Fernandez, I.; Cheben, P.; Mashanovich, G. Z.

    2016-03-01

    This paper discusses some of the remaining challenges for silicon photonics, and how we at Southampton University have approached some of them. Despite phenomenal advances in the field of Silicon Photonics, there are a number of areas that still require development. For short to medium reach applications, there is a need to improve the power consumption of photonic circuits such that inter-chip, and perhaps intra-chip applications are viable. This means that yet smaller devices are required as well as thermally stable devices, and multiple wavelength channels. In turn this demands smaller, more efficient modulators, athermal circuits, and improved wavelength division multiplexers. The debate continues as to whether on-chip lasers are necessary for all applications, but an efficient low cost laser would benefit many applications. Multi-layer photonics offers the possibility of increasing the complexity and effectiveness of a given area of chip real estate, but it is a demanding challenge. Low cost packaging (in particular, passive alignment of fibre to waveguide), and effective wafer scale testing strategies, are also essential for mass market applications. Whilst solutions to these challenges would enhance most applications, a derivative technology is emerging, that of Mid Infra-Red (MIR) silicon photonics. This field will build on existing developments, but will require key enhancements to facilitate functionality at longer wavelengths. In common with mainstream silicon photonics, significant developments have been made, but there is still much left to do. Here we summarise some of our recent work towards wafer scale testing, passive alignment, multiplexing, and MIR silicon photonics technology.

  10. Kedi ve Köpeklerde Diabetes Mellitus.

    OpenAIRE

    ŞİMŞEK, Aynur; İÇEN, Hasan

    2008-01-01

    Diabetes mellitus polidipsi, poliüri ve polifaji gibi klinik bulgularla karakterize endokrin bir hastalıktır. Bu derlemede, kedi ve köpeklerde yaygın olan hastalığın etiyoloji, patogenezis, kliniklaboratuar bulguları, tanı, ayırıcı tanı ve sağaltımına yönelik bilgilerin verilmesi amaçlanmıştır

  11. 47 CFR 97.513 - VE session manager requirements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false VE session manager requirements. 97.513 Section... SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.513 VE session manager requirements. (a) A VE session manager may be selected by the VE team for each examination session. The VE session...

  12. VE for Lua game programming

    CERN Document Server

    Mishra, Brij Bhushan

    2013-01-01

    This book follows a tutorial approach with examples and step-by-step instructions to help explain the key concepts of the LÖVE framework as well as everything you need to know about game development using the Lua programming language.LÖVE2d for Lua Game Programming is for anyone who is interested in learning about desktop game development.

  13. Hücre siklusu ve kanser

    OpenAIRE

    Cabadak, Hülya

    2008-01-01

    Hücre çogalması ve hücre siklusunun ilerlemesi büyümenin kontrolünde rolü olan genlerin ekspresyonu ile baglantılıdır. Ökaryot hücre siklusuM(mitoz) G , S ve G fazlarından olusmaktadır. Bu süreçte hücre uyarımı ve büyüme meydana gelir veya hücre G fazında durmaktadır. Hücre siklusunda G -S geçisinde, G -Mgeçisinde ve metafaz-anafaz geçisinde kontrol noktaları bulunmaktadır. Hücre siklusu siklin bagımlı kinazlar (cdk, katalitik altbirim) ve siklin (cyc, düzenleyici altbirim) tarafı...

  14. Mo(ve)ment-methodology

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Christian Celosse-Andersen, Martin

    2018-01-01

    This paper describes the theoretical basis for and development of a moment-movement research methodology, based on an integration of critical psychological practice research and critical ethnographic social practice theory. Central theoretical conceptualizations, such as human agency, life...... conditions and identity formation, are discussed in relation to criminological theories of gang desistance. The paper illustrates how the mo(ve)ment methodology was applied in a study of comprehensive processes of identity (re)formation and gang exit processes. This study was conducted with Martin, a former....... This is a moment which captures Martin’s complex and ambiguous feelings of conflictual concerns, frustration, anger, and a new feeling of insecurity in his masculinity, as well as engagement and a sense of deep meaningfulness as he becomes a more reflective academic. All these conflicting feelings also give...

  15. Genève Reconnaissante

    CERN Multimedia

    2001-01-01

    Robert Cailliau (centre), with Geneva's Mayor Alain Vaissade (left) and Jean Erhardt, Secretary General of the Administrative Council of Geneva (right). Geneva recognised the contribution of two CERN people to the reputation of the city last Tuesday when Mayor Alain Vaissade presented the Genève Reconaissante Medal to Tim Berners-Lee and Robert Cailliau. Berners-Lee, who was not able to be present in person, invented the World Wide Web at CERN just over a decade ago, while Cailliau was his first collaborator. Quoting Cailliau, Vaissade said that whilst there is no doubt that something like the Web would have appeared sooner or later, the fact that it happened at CERN, in Geneva, was no accident. Both the Laboratory and the city are places where people from around the world meet and work in harmony.

  16. 40 CFR 35.926 - Value engineering (VE).

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Value engineering (VE). 35.926 Section... engineering (VE). (a) Value engineering proposal. All step 2 grant applications for projects having a... completion of VE analysis and submittal of VE summary reports). (b) Value engineering analysis. For projects...

  17. Gıdalar ve Mikrobiyolojik Riskler I

    Directory of Open Access Journals (Sweden)

    Velittin Gürgün

    2015-02-01

    Full Text Available Enfeksiyona neden olan ve toksijenik mikroorganizmalarla bulaşan gıdaların tüketilmesi sonucu görülen hastalıklar, acı çekmenin ve ölümlerin en önemli nedenlerinden biridir (Alen ve Kaferstein, 1983. Afrika ve Latin Amerika ile Çin dışındaki Asya ülkelerindeki 5 yaşın altındaki çocuklarda, yılda bir milyarın üzerinde gastroenterik vakaların görüldüğü ve kontamine gıdaların tüketilmesi nedeni ile de bu çocuklardan en az beş milyonunun öldüğü tahmin edilmektedir (Kaferstien ve Sims, 1987. Meksika ve Tayland gibi ülkelerde 0-4 yaş grubun çocukların, en az yarısının Campylobacter’in neden olduğu bağırsak enfeksiyonuna yakalandıkları sanılmaktadır. Avrupa’da ise gıdalardan kaynaklanan hastalıklar, solunum hastalıklarından sonra ikinci sırada yer almakta olup, bir çok Avrupa ülkesinde akut gastro-enteritis hastalığının yılda bir milyon kişiden ellibininde görüldüğü, hatta Hollanda’da bu oranın üçyüzbin olduğu tespit edilmiş bulunmaktadır (Guiguet vd. 1992; Notermans ve Van Der Giessen, 1993. Amerika Birleşik Devletleri için yürütülen tahminlerin bu sayıların da üstünde olduğu ve her yıl ABD’de bir milyon kişiden üçyüzellibin kişinin akut gastroenterik hastalıklara uğradıkları ve bunun da ağırlıklı olarak kontamine gıdalardan kaynaklandığı varsayılmaktadır (Archer ve Kvenberg, 1985. Her ne kadar gelişmiş ülkelerde görülen gıda kaynaklı hastalıklar gelişmekte olan ülkelerdekine göre oldukça düşükse de, sıkça kronikleşerek romatizmal hastalıklar (ankylosing spondylitis ve Reiter’s sendromu beslenme ve emilim bozukluğu problemleri, hemolotik-üremik sendromlar (Escherichia coli’nin özellikle 0157: H7 serotipinin ürettiği verotoksinden dolayı, damar sertliği (atherosclerosis ve Campylobacter türlerinin enfeksiyonunu takiben görülen Guillain-Barre sendromu sonucunu doğurmaktadır (Archer, 1984, 1987; Archer ve

  18. Palmar, Patellar, and Pedal Human Remains from Pavlov

    Czech Academy of Sciences Publication Activity Database

    Trinkaus, E.; Wojtal, P.; Wilczyński, J.; Sázelová, Sandra; Svoboda, Jiří

    2017-01-01

    Roč. 2017, June (2017), s. 73-101 ISSN 1545-0031 Institutional support: RVO:68081758 Keywords : Gravettian * human remains * isolated bones * anatomically modern humans * Upper Paleolithic Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Archaeology http://paleoanthro.org/media/journal/content/PA20170073.pdf

  19. Hamilelik ve periodontal hastalık

    OpenAIRE

    Sağlam, Ebru; Saruhan, Nesrin; Çanakçı, Cenk Fatih

    2015-01-01

    Hamileliğe bağlı olarak annede görülen bazı immünolojik değişiklikler enfeksiyonlara yatkınlığı artırmaktadır. Periodontal hastalık, başlıca sebebi mikrobiyal dental plak olan, multifaktöriyel ve çeşitli şiddetlerde görülen yaygın bir hastalıktır. Periodontal hastalığın klinik olarak birçok tanı kriteri bulunmaktadır. Hamilelik ve periodontal enflamasyon arasındaki ilişki uzun yıllardır bilinmektedir. Periodontal hastalık, hamilelerde sistemik durumu etkilemektedir ve fetusa da olumsuz etkile...

  20. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Rasime DEMİREL

    2010-10-01

    Full Text Available Eskişehir (Türkiye’deki farklı marketlerden toplanmış olan şişelenmiş doğal ve mineral suların mikrobiyal kalitesi incelenmiştir. Membran filtrasyon tekniği uygulanarak su örneklerinin kalitesi; toplam koliform, Escherichia coli, Enterococcus spp., Aeromonas hydrophila’nın varlığı ve miktarı yönünden analiz edilmiştir. Aerobik bakteriler 22 ve 37 ºC’de inkübasyonu sonucunda ml’deki heterotrofik bakteri sayısı (HPC olarak belirlenmiştir. Şişelenmiş mineral su örneklerinde Bacillus türleri belirlenirken, şişelenmiş içme suyu örneklerinde herhangi bir bakteri ya da kontaminasyon bulunmamıştır

  1. Melatonin ve Klinik Önemi

    OpenAIRE

    Fehmi, Özgüner; Özcankaya, Ramazan; Delibaş, Namık; Koyu, Ahmet; Çalışkan, Sadettin

    2009-01-01

    SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1995 Aralık; 2(4) Melatonin ve Klinik Önemi Fehmi Özgüner Ramazan Özcankaya Namık Delibaş Ahmet Koyu Sadettin Çalışkan . Özet Melatonin karanlık periyotta sentezlenir ve salınır, ayrıca karanlığın süresi hakkındaki bilginin değerlendirilmesine aracılık eder. Melatonin sirkadiyan ritmi, gençlerde oldukça düzenlidir, yaşlılıkta sıklıkla siklus bozulma gösterir ve bir hipomelatoninemi sendromu ola...

  2. Probiyotik Mayalar ve Özellikleri

    Directory of Open Access Journals (Sweden)

    Hatice Yıldıran

    2017-10-01

    Full Text Available Probiyotikler tüketicinin sağlığı üzerinde olumlu etkileri olan mikroorganizmalardır. Probiyotik uygulamalarının sağlık üzerine etkileri hakkında yapılmış pekçok araştırma bulunmaktadır. En yaygın kullanılan probiyotik bakteriler; bifidobakteriler ve laktobasiller, laktokoklar ve streptokoklar gibi laktik asit bakterileridir. İnsanlar için probiyotik olarak kullanılan mikroorganizmalar arasında ayrıca mayalar, basiller ve enterokoklar da bulunmaktadır. Probiyotik mayalar son yıllarda bilim insanları için ilgi çekici bir alan olmuştur. Yapılan bazı çalışmalar Saccharomyces cinsine ait türlerin antibakteriyel ve probiyotik özelliklere sahip olabileceklerini göstermiştir. Saccharomyces boulardii yıllardır insanları farklı gastrointestinal rahatsızlıklarından korumak veya hastalıklardan iyileştirmek amacıyla probiyotik olarak kullanılan, patojenik olmayan bir mayadır. S. boulardii özellikle ilaç endüstrisinde genellikle liyofilize formda kullanılmaktadır. Yapılan bu derleme çalışmasında probiyotikler, mayaların probiyotik olma özellikleri ve probiyotik mayaların kullanım alanları hakkında bilgiler verilmiş ve bu alanda yapılan araştırmalardan örnekler sunulmuştur.

  3. Using VE to Strategically Plan Our Future

    Energy Technology Data Exchange (ETDEWEB)

    Margie Jeffs; Lori Braase; Alison Conner; Darcie Martinson; Jodi Grgich

    2009-06-01

    The Value Engineering (VE) Methodology is an effective tool for business or project strategic planning. In conjunction with the “Balanced Scorecard Approach” (Drs. Robert Kaplan, PhD, and David Norton, PhD, from the Balanced Scorecard Collaborative/Palladium Group), function analysis can be used to develop strategy maps and scorecards. The FAST diagram provides an integrated approach to strategy map development by formulating a cause and effect relationship and establishing the “how” and “why” behind the strategy map. By utilizing the VE Job Plan, one is able to move from strategic thinking all the way through to execution of the strategy.

  4. Van Otlu Peynirinin Yapılışı ve Mikrobiyolojik, Fiziksel ve Kimyasal Nitelikleri

    Directory of Open Access Journals (Sweden)

    Ahmet Kurt

    2015-02-01

    Full Text Available Bu araştırmada 10 adet taze Van Otlu peyniri örneklerine; mikrobiyolojik, fiziksel ve kimyasal analizler uygulanmıştır. Peynir teknolojisinde, sağlık, teknik ve ekonomik yönden önemli olan toplam koliform, süt asidi, lipolitik ve proteolitik mikroorganizmalarla maya ve küflerin sayısal değerleri yanında rutubet, yağ, yağsız kurumadde, kurumaddede yağ, protein, suda eriyen protein, kül, tuz, saf kül, kurumaddede tuz ve % asitlik oranları, peynir örneklerinde ayrı ayrı saptanmıştır. Elde edilen sonuçlara göre peynir yapımı çok dağınık ve ilkel karakter arz etmektedir. Peynirlerin yapımındaki farklı uygulamalar, teknik bilgi ve yöntem noksanlığı yüzünden, gerek mikrobiyolojik analiz ve gerekse fiziksel ve kimyasal analiz sonuçları örnekten örneğe önemli fraklılıklar göstermiştir. Peynir örneklerinde saptanan Koliform organizma sayıları, hem sağlık yönünden hem de peynirlerin olgunlaşmalarında sorunlara neden olabilecek düzeydedir.

  5. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-12-01

    Full Text Available Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Chemical Abstracts Service , EBSCO Discovery Service, Google Scholar, WorldCat ve Zentralblatt MATH indekslerinde taranmaktadır.Süleyman Demirel University Journal of Natural and Applied Sciences is indexed in Chemical Abstracts Service, EBSCO Discovery Service, Google Scholar, WorldCat and Zentralblatt MATH.

  6. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Kazım UYSAL

    2011-02-01

    Full Text Available Yoğun zirai faaliyetlerin yapıldığı Antalya’nın batı sahillerinden yakalanan ekonomik önemi olan bazı deniz balıklarının (Diplodus sargus, Siganus rivulatus, Lithognathus mormyrus, Liza aurata, Chelon labrasus kas, deri ve solungaçlarındaki bakır, çinko, mangan, demir ve magnezyum (Genellikle zirai aktivitelerden kaynaklanırlar biyoakümülasyon seviyeleri araştırılmıştır. Balıkların dokularında incelenen elementlerin minimum ve maksimum seviyeleri (mg kg-1 yaş ağırlık bakır için 0.541.69; çinko için 4.14-407.23; mangan için 0.15-9.17; demir için 3.45-104.49 ve magnezyum için 204.33- 784.30 olarak tespit edilmiştir. İncelenen elementlerin en düşük biyoakümülasyon seviyeleri kas dokularda, en yüksek seviyeler (Bakır hariç ise solungaçlarda tespit edilmiştir. İncelenen türlerin kas dokularındaki bakır ve çinko seviyeleri (Dünya Sağlık Örgütü (WHO, Gıda ve Tarım Örgütü (FAO ve Türk Gıda Kodeksi’nde belirtilen kabul edilebilir maksimum seviyelerden daha düşük, bazı türlerin (D. sargus, S. rivulatus, L. mormyrus and L. aurata derilerinde bulunan çinko seviyeleri ise kabul edilebilir maksimum seviyelerden daha yüksek bulunmuştur

  7. Fish remains and humankind: part two

    Directory of Open Access Journals (Sweden)

    Andrew K G Jones

    1998-07-01

    Full Text Available The significance of aquatic resources to past human groups is not adequately reflected in the published literature - a deficiency which is gradually being acknowledged by the archaeological community world-wide. The publication of the following three papers goes some way to redress this problem. Originally presented at an International Council of Archaeozoology (ICAZ Fish Remains Working Group meeting in York, U.K. in 1987, these papers offer clear evidence of the range of interest in ancient fish remains across the world. Further papers from the York meeting were published in Internet Archaeology 3 in 1997.

  8. Why Agricultural Educators Remain in the Classroom

    Science.gov (United States)

    Crutchfield, Nina; Ritz, Rudy; Burris, Scott

    2013-01-01

    The purpose of this study was to identify and describe factors that are related to agricultural educator career retention and to explore the relationships between work engagement, work-life balance, occupational commitment, and personal and career factors as related to the decision to remain in the teaching profession. The target population for…

  9. Juveniles' Motivations for Remaining in Prostitution

    Science.gov (United States)

    Hwang, Shu-Ling; Bedford, Olwen

    2004-01-01

    Qualitative data from in-depth interviews were collected in 1990-1991, 1992, and 2000 with 49 prostituted juveniles remanded to two rehabilitation centers in Taiwan. These data are analyzed to explore Taiwanese prostituted juveniles' feelings about themselves and their work, their motivations for remaining in prostitution, and their difficulties…

  10. Kadav Moun PSA (:60) (Human Remains)

    Centers for Disease Control (CDC) Podcasts

    2010-02-18

    This is an important public health announcement about safety precautions for those handling human remains. Language: Haitian Creole.  Created: 2/18/2010 by Centers for Disease Control and Prevention (CDC).   Date Released: 2/18/2010.

  11. The Annuity Puzzle Remains a Puzzle

    NARCIS (Netherlands)

    Peijnenburg, J.M.J.; Werker, Bas; Nijman, Theo

    We examine incomplete annuity menus and background risk as possible drivers of divergence from full annuitization. Contrary to what is often suggested in the literature, we find that full annuitization remains optimal if saving is possible after retirement. This holds irrespective of whether real or

  12. Explosives remain preferred methods for platform abandonment

    International Nuclear Information System (INIS)

    Pulsipher, A.; Daniel, W. IV; Kiesler, J.E.; Mackey, V. III

    1996-01-01

    Economics and safety concerns indicate that methods involving explosives remain the most practical and cost-effective means for abandoning oil and gas structures in the Gulf of Mexico. A decade has passed since 51 dead sea turtles, many endangered Kemp's Ridleys, washed ashore on the Texas coast shortly after explosives helped remove several offshore platforms. Although no relationship between the explosions and the dead turtles was ever established, in response to widespread public concern, the US Minerals Management Service (MMS) and National Marine Fisheries Service (NMFS) implemented regulations limiting the size and timing of explosive charges. Also, more importantly, they required that operators pay for observers to survey waters surrounding platforms scheduled for removal for 48 hr before any detonations. If observers spot sea turtles or marine mammals within the danger zone, the platform abandonment is delayed until the turtles leave or are removed. However, concern about the effects of explosives on marine life remains

  13. Analysis of Naïve Bayes Algorithm for Email Spam Filtering across Multiple Datasets

    Science.gov (United States)

    Fitriah Rusland, Nurul; Wahid, Norfaradilla; Kasim, Shahreen; Hafit, Hanayanti

    2017-08-01

    E-mail spam continues to become a problem on the Internet. Spammed e-mail may contain many copies of the same message, commercial advertisement or other irrelevant posts like pornographic content. In previous research, different filtering techniques are used to detect these e-mails such as using Random Forest, Naïve Bayesian, Support Vector Machine (SVM) and Neutral Network. In this research, we test Naïve Bayes algorithm for e-mail spam filtering on two datasets and test its performance, i.e., Spam Data and SPAMBASE datasets [8]. The performance of the datasets is evaluated based on their accuracy, recall, precision and F-measure. Our research use WEKA tool for the evaluation of Naïve Bayes algorithm for e-mail spam filtering on both datasets. The result shows that the type of email and the number of instances of the dataset has an influence towards the performance of Naïve Bayes.

  14. The Nature of VeLLOs

    Science.gov (United States)

    Huard, Tracy L.; Pound, Marc W.; Mundy, Lee; Dunham, Michael

    2018-01-01

    Very Low Luminosity Objects (VeLLOs) are young stellar sources that are defined by luminosities less than 0.1 solar luminosity and rising mid-infrared spectral energy distributions. But, what exactly are they? Brown dwarfs or low-mass stars in formation? Systems exhibiting low accretion rates? Extremely young objects? We have completed an ALMA survey of 33 candidates in the nearby Serpens, Ophiuchus, and Lupus star-forming molecular clouds. Continuum emission at 1.3 mm, consistent with the presence of an inner envelope and/or disk, was detected toward 17 candidates, with at least 6 of these candidates exhibiting CO outflow emission, suggesting ongoing formation. We will present these observations and results, and discuss their implications concerning the nature of VeLLOs.

  15. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2016-04-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, DOAJ, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  16. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2016-08-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  17. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Nalan YILMAZ SARIÖZLÜ

    2010-10-01

    Full Text Available Eskişehir/Türkiye’deki ılıca sularındaki bakteriyel topluluğun ortaya konulması ve incelenmesi için 7 ılıca su örneği 7 farklı ılıcadan toplanmıştır. Tüm örnekler dört farklı besi ortamına (nutrient agar, su-maya ekstraktı agar, triptik soy agar, nişasta-kazein agar inoküle edilmiştir. 50 °C’de 14 günlük inkübasyondan sonra tüm bakteri kolonilerinin sayımı yapılıp saflaştırılmıştır. Tüm izolatların gram reaksiyonları, katalaz veoksidazözellikleri belirlenmişve BIOLOG, VITEK veotomatikribotiplendirme sisteminde (RiboPrinter incelenmişlerdir. Bu bakterilerin ampisilin, gentamisin, trimetoprim-sülfametoksazol ve tetrasiklin antibiyotiklerine karşı dirençliliği incelenmiştir. Sonuç olarak normal insan florasına ilaveten ısıya dirençli patojenik mikroorganizmalar incelenen alandaki ılıca sularında (43-50 °C belirlenmiştir. Altı genusa ait 10 farklı tür Alysiella filiformis, Bordetella bronchiseptica, B. pertussis, Molexalla caprae, M. caviae, M. cuniculi, M. phenylpyruvica, Roseomonas fauriae, Delftia acidovorans ve Pseudomonas taetrolens olarak tanımlanmıştır

  18. Davras Dagı (Isparta ve Çevresinin Orman ve Çalı Vejetasyonu

    Directory of Open Access Journals (Sweden)

    Coşkun SAĞLAM

    2009-04-01

    Full Text Available Bu vejetasyon çalısması, 2002-2005 yılları arasında Batı Toroslar'da yer alan Davras Dagı ve çevresinde gerçeklestirildi. Vejetasyon Braun-Blanquet (1964 metoduna göre analiz edilerek orman ve çalı vejetasyonuna ait yedi birlik tespit edildi. Bunlardan bes tanesi yenidir. Orman vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 1. Minuartio globulosi – Juniperetum excelsae ass. nova 2. Sileno squamigeri – Quercetum cerridis ass. nova 3. Astragalo oxytropifolii – Pinetum caramanicae ass. nova Alyans : Lonicero nummulariaefoliae – Cedrion libani Quézel, Barbéro ve Akman 1978 4. Veronico syriaci – Cedretum libani ass. nova 5. Diantho cibrarii – Quercetum vulcanicae Kurt et al. 1996 Sınıf : Quercetea ilicis Br.-Bl., 1947 Ordo : Quercetalia ilicis Br.-Bl., 1947, Rivaz Martinez, 1974 Alyans : Quercion cocciferae Quézel, Barbéro, Akman, 1978 6. Hyperico polyphylli – Pinetum brutiae ass. nova Çalı Vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 7. Astragalo atropurpureus– Quercetum cocciferae Kargıoglu, 19

  19. Cortisol awakening response in drug-naïve panic disorder

    Directory of Open Access Journals (Sweden)

    Jakuszkowiak-Wojten K

    2016-06-01

    Full Text Available Katarzyna Jakuszkowiak-Wojten, Jerzy Landowski, Mariusz S Wiglusz, Wiesław Jerzy Cubała Department of Psychiatry, Medical University of Gdansk, Gdansk, Poland Background: It is unclear whether hypothalamic–pituitary–adrenal axis is involved in the pathophysiology of panic disorder (PD. The findings remain inconsistent. Cortisol awakening response (CAR is a noninvasive biomarker of stress system activity. We designed the study to assess CAR in drug-naïve PD patients.   Materials and methods: We assessed CAR in 14 psychotropic drug-naïve outpatients with PD and 14 healthy controls. The severity of PD was assessed with Panic and Agoraphobia Scale. The severity of anxiety and depression was screened with Hospital Anxiety and Depression Scale.   Results: No significant difference in CAR between PD patients and control group was found. No correlations were observed between CAR and anxiety severity measures in PD patients and controls.   Limitations: The number of participating subjects was relatively small, and the study results apply to nonsuicidal drug-naïve PD patients without agoraphobia and with short-illness duration. There was a lack of control on subjects’ compliance with the sampling instructions.  Conclusion: The study provides no support for elevated CAR levels in drug-naïve PD patients without agoraphobia. Keywords: panic disorder, PD, CAR, cortisol awakening response, HPA axis, hypothalamic–pituitary–adrenal axis

  20. Decomposition Technique for Remaining Useful Life Prediction

    Science.gov (United States)

    Saha, Bhaskar (Inventor); Goebel, Kai F. (Inventor); Saxena, Abhinav (Inventor); Celaya, Jose R. (Inventor)

    2014-01-01

    The prognostic tool disclosed here decomposes the problem of estimating the remaining useful life (RUL) of a component or sub-system into two separate regression problems: the feature-to-damage mapping and the operational conditions-to-damage-rate mapping. These maps are initially generated in off-line mode. One or more regression algorithms are used to generate each of these maps from measurements (and features derived from these), operational conditions, and ground truth information. This decomposition technique allows for the explicit quantification and management of different sources of uncertainty present in the process. Next, the maps are used in an on-line mode where run-time data (sensor measurements and operational conditions) are used in conjunction with the maps generated in off-line mode to estimate both current damage state as well as future damage accumulation. Remaining life is computed by subtracting the instance when the extrapolated damage reaches the failure threshold from the instance when the prediction is made.

  1. Industry remains stuck in a transitional mode

    International Nuclear Information System (INIS)

    Garb, F.A.

    1991-01-01

    The near future for industry remains foggy for several obvious reasons. The shake-up of the Soviet Union and how the pieces will reform remains unclear. How successful efforts are to privatize government oil company operations around the world has yet to be determined. A long sought peace in the Middle East seems to be inching closer, but will this continue? If it does continue, what impact will it have on world energy policy? Will American companies, which are now transferring their attention to foreign E and P, also maintain an interest in domestic activities? Is the U.S. economy really on the upswing? We are told that the worst of the recession is over, but try telling this to thousands of workers in the oil patch who are being released monthly by the big players in domestic operations. This paper reports that 1992 should be a better year than 1991, if measured in opportunity. There are more exploration and acquisition options available, both domestically and internationally, than there have been in years. Probably more opportunities exist than there are players-certainly more than can be funded with current financial resources

  2. Shotgun microbial profiling of fossil remains

    DEFF Research Database (Denmark)

    Der Sarkissian, Clio; Ermini, Luca; Jónsson, Hákon

    2014-01-01

    the specimen of interest, but instead reflect environmental organisms that colonized the specimen after death. Here, we characterize the microbial diversity recovered from seven c. 200- to 13 000-year-old horse bones collected from northern Siberia. We use a robust, taxonomy-based assignment approach...... to identify the microorganisms present in ancient DNA extracts and quantify their relative abundance. Our results suggest that molecular preservation niches exist within ancient samples that can potentially be used to characterize the environments from which the remains are recovered. In addition, microbial...... community profiling of the seven specimens revealed site-specific environmental signatures. These microbial communities appear to comprise mainly organisms that colonized the fossils recently. Our approach significantly extends the amount of useful data that can be recovered from ancient specimens using...

  3. Some remaining problems in HCDA analysis

    International Nuclear Information System (INIS)

    Chang, Y.W.

    1981-01-01

    The safety assessment and licensing of liquid-metal fast breeder reactors (LMFBRs) requires an analysis on the capability of the reactor primary system to sustain the consequences of a hypothetical core-disruptive accident (HCDA). Although computational methods and computer programs developed for HCDA analyses can predict reasonably well the response of the primary containment system, and follow up the phenomena of HCDA from the start of excursion to the time of dynamic equilibrium in the system, there remain areas in the HCDA analysis that merit further analytical and experimental studies. These are the analysis of fluid impact on reactor cover, three-dimensional analysis, the treatment of the perforated plates, material properties under high strain rates and under high temperatures, the treatment of multifield flows, and the treatment of prestressed concrete reactor vessels. The purpose of this paper is to discuss the structural mechanics of HCDA analysis in these areas where improvements are needed

  4. Political, energy events will remain interwoven

    International Nuclear Information System (INIS)

    Jones, D.P.

    1991-01-01

    This paper reports that it is possible to discuss the significance of political and energy events separately, but, in truth, they are intricately interwoven. Furthermore, there are those who will argue that since the two are inseparable, the future is not predictable; so why bother in the endeavor. It is possible that the central point of the exercise may have been missed-yes, the future is unpredictable exclamation point However, the objective of prediction is secondary. The objective of understanding the dynamic forces of change is primary exclamation point With this view of recent history, it is perhaps appropriate to pause and think about the future of the petroleum industry. The future as shaped by political, energy, economic, environmental and technological forces will direct our lives and markets during this decade. Most importantly, what will be the direction that successful businesses take to remain competitive in a global environment? These are interesting issues worthy of provocative thoughts and innovative ideas

  5. Nuclear remains an economic and ecologic asset

    International Nuclear Information System (INIS)

    Le Ngoc, Boris

    2015-01-01

    The author herein outlines the several benefits of nuclear energy and nuclear industry for France. He first outlines that France possesses 97 per cent of de-carbonated electricity thanks to nuclear energy (77 pc) and renewable energies (20 pc, mainly hydraulic), and that renewable energies must be developed in the building and transport sectors to be able to get rid of the environmentally and financially costly fossil energies. He outlines that reactor maintenance and the nuclear fuel cycle industry are fields of technological leadership for the French nuclear industry which is, after motor industry and aircraft industry, the third industrial sector in France. He indicates that nuclear electricity is to remain the most competitive one, and that nuclear energy and renewable energies must not be opposed to it but considered as complementary in the struggle against climate change, i.e. to reduce greenhouse gas emissions and to get rid of the prevalence of fossil energies

  6. Population cycles: generalities, exceptions and remaining mysteries

    Science.gov (United States)

    2018-01-01

    Population cycles are one of nature's great mysteries. For almost a hundred years, innumerable studies have probed the causes of cyclic dynamics in snowshoe hares, voles and lemmings, forest Lepidoptera and grouse. Even though cyclic species have very different life histories, similarities in mechanisms related to their dynamics are apparent. In addition to high reproductive rates and density-related mortality from predators, pathogens or parasitoids, other characteristics include transgenerational reduced reproduction and dispersal with increasing-peak densities, and genetic similarity among populations. Experiments to stop cyclic dynamics and comparisons of cyclic and noncyclic populations provide some understanding but both reproduction and mortality must be considered. What determines variation in amplitude and periodicity of population outbreaks remains a mystery. PMID:29563267

  7. Does hypertension remain after kidney transplantation?

    Directory of Open Access Journals (Sweden)

    Gholamreza Pourmand

    2015-05-01

    Full Text Available Hypertension is a common complication of kidney transplantation with the prevalence of 80%. Studies in adults have shown a high prevalence of hypertension (HTN in the first three months of transplantation while this rate is reduced to 50- 60% at the end of the first year. HTN remains as a major risk factor for cardiovascular diseases, lower graft survival rates and poor function of transplanted kidney in adults and children. In this retrospective study, medical records of 400 kidney transplantation patients of Sina Hospital were evaluated. Patients were followed monthly for the 1st year, every two months in the 2nd year and every three months after that. In this study 244 (61% patients were male. Mean ± SD age of recipients was 39.3 ± 13.8 years. In most patients (40.8% the cause of end-stage renal disease (ESRD was unknown followed by HTN (26.3%. A total of 166 (41.5% patients had been hypertensive before transplantation and 234 (58.5% had normal blood pressure. Among these 234 individuals, 94 (40.2% developed post-transplantation HTN. On the other hand, among 166 pre-transplant hypertensive patients, 86 patients (56.8% remained hypertensive after transplantation. Totally 180 (45% patients had post-transplantation HTN and 220 patients (55% didn't develop HTN. Based on the findings, the incidence of post-transplantation hypertension is high, and kidney transplantation does not lead to remission of hypertension. On the other hand, hypertension is one of the main causes of ESRD. Thus, early screening of hypertension can prevent kidney damage and reduce further problems in renal transplant recipients.

  8. A CONTENT ANALYSIS OF KEYWORD OF THESES IN THE FIELD OF TURKISH EDUCATION AND TEACHING TÜRKÇENİN EĞİTİMİ VE ÖĞRETİMİ ALANINDA YAPILAN YÜKSEK LİSANS TEZLERİNDE GEÇEN ANAHTAR KELİMELERE DÖNÜK BİR İÇERİK ANALİZİ

    Directory of Open Access Journals (Sweden)

    Oğuzhan SEVİM

    2012-01-01

    Full Text Available The purpose of this study is to examine and group thematically keywords in graduate dissertations written in the Turkish education. Meta-analysis method was used in research. The study was carried out on 335 graduate dissertations written between 2005-2010 in the field of Turkish education. The data werw collected from document analysis technique. Keywords listed by researcher was studied to group thematically. As a result of the study, it was understood that not only related to basic language skills but also literature,, teacher competence, children literature, textbook review were studied in the field of Turkish education. Looking at the master’s thesis on the basic language skills, it was seen that studies were concentrated in the field of reading and writing; areas of speeking and listening were neglected. Bu çalışmanın amacı Türkçe eğitimi alanında yazılmış yüksek lisans tezlerinde geçen anahtar kelimeleri incelemek ve tematik olarak gruplandırmaktır. Araştırmada olgubilim deseni kullanılmıştır. Çalışma, 2005-2010 yılları arasında Türkçe Eğitimi alanında yazılmış 335 yüksek lisans tezi üzerinde gerçekleştirilmiştir. Araştırmanın verileri doküman incelemesi tekniğiyle toplanmıştır. Listelenen anahtar kelimeler, tematik olarak gruplandırılmaya çalışılmıştır. Çalışmanın sonucunda Türkçe eğitimi alanında yazılmış olan yüksek lisans tezlerinin yalnızca temel dil becerileriyle ilgili olmadığı; edebiyat, öğretmen yeterliliği, çocuk edebiyatı, ders kitabı incelemesi konularında da çalışıldığı anlaşılmıştır. Temel dil beceriyle ilgili olan yüksek lisans tezlerine bakıldığında çalışmaların okuma ve yazma alanlarında yoğunlaştığı, konuşma ve dinleme alanlarının ise ihmal edildiği görülmüştür.

  9. The Human Remains from HMS Pandora

    Directory of Open Access Journals (Sweden)

    D.P. Steptoe

    2002-04-01

    Full Text Available In 1977 the wreck of HMS Pandora (the ship that was sent to re-capture the Bounty mutineers was discovered off the north coast of Queensland. Since 1983, the Queensland Museum Maritime Archaeology section has carried out systematic excavation of the wreck. During the years 1986 and 1995-1998, more than 200 human bone and bone fragments were recovered. Osteological investigation revealed that this material represented three males. Their ages were estimated at approximately 17 +/-2 years, 22 +/-3 years and 28 +/-4 years, with statures of 168 +/-4cm, 167 +/-4cm, and 166cm +/-3cm respectively. All three individuals were probably Caucasian, although precise determination of ethnicity was not possible. In addition to poor dental hygiene, signs of chronic diseases suggestive of rickets and syphilis were observed. Evidence of spina bifida was seen on one of the skeletons, as were other skeletal anomalies. Various taphonomic processes affecting the remains were also observed and described. Compact bone was observed under the scanning electron microscope and found to be structurally coherent. Profiles of the three skeletons were compared with historical information about the 35 men lost with the ship, but no precise identification could be made. The investigation did not reveal the cause of death. Further research, such as DNA analysis, is being carried out at the time of publication.

  10. SMART POINT CLOUD: DEFINITION AND REMAINING CHALLENGES

    Directory of Open Access Journals (Sweden)

    F. Poux

    2016-10-01

    Full Text Available Dealing with coloured point cloud acquired from terrestrial laser scanner, this paper identifies remaining challenges for a new data structure: the smart point cloud. This concept arises with the statement that massive and discretized spatial information from active remote sensing technology is often underused due to data mining limitations. The generalisation of point cloud data associated with the heterogeneity and temporality of such datasets is the main issue regarding structure, segmentation, classification, and interaction for an immediate understanding. We propose to use both point cloud properties and human knowledge through machine learning to rapidly extract pertinent information, using user-centered information (smart data rather than raw data. A review of feature detection, machine learning frameworks and database systems indexed both for mining queries and data visualisation is studied. Based on existing approaches, we propose a new 3-block flexible framework around device expertise, analytic expertise and domain base reflexion. This contribution serves as the first step for the realisation of a comprehensive smart point cloud data structure.

  11. Capturing Human Naïve Pluripotency in the Embryo and in the Dish.

    Science.gov (United States)

    Zimmerlin, Ludovic; Park, Tea Soon; Zambidis, Elias T

    2017-08-15

    Although human embryonic stem cells (hESCs) were first derived almost 20 years ago, it was only recently acknowledged that they share closer molecular and functional identity to postimplantation lineage-primed murine epiblast stem cells than to naïve preimplantation inner cell mass-derived mouse ESCs (mESCs). A myriad of transcriptional, epigenetic, biochemical, and metabolic attributes have now been described that distinguish naïve and primed pluripotent states in both rodents and humans. Conventional hESCs and human induced pluripotent stem cells (hiPSCs) appear to lack many of the defining hallmarks of naïve mESCs. These include important features of the naïve ground state murine epiblast, such as an open epigenetic architecture, reduced lineage-primed gene expression, and chimera and germline competence following injection into a recipient blastocyst-stage embryo. Several transgenic and chemical methods were recently reported that appear to revert conventional human PSCs to mESC-like ground states. However, it remains unclear if subtle deviations in global transcription, cell signaling dependencies, and extent of epigenetic/metabolic shifts in these various human naïve-reverted pluripotent states represent true functional differences or alternatively the existence of distinct human pluripotent states along a spectrum. In this study, we review the current understanding and developmental features of various human pluripotency-associated phenotypes and discuss potential biological mechanisms that may support stable maintenance of an authentic epiblast-like ground state of human pluripotency.

  12. Aileler, Öğretmenler ve Dil ve Konuşma Terapistlerinin Çocuklardaki Dil ve Konuşma Bozukluklarına Yönelik Tutum ve Bilgilerinin Değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Bülent TOĞRAM

    2015-12-01

    Full Text Available Çocuklardaki iletişim sorunları aile bildirimleri, öğretmen raporları ve dil ve konuşma terapistleri (DKT tarafından yapılan değerlendirmeler ile saptanmaktadır. Dil ve konuşma bozukluklarının önlenmesi ve terapisinde işbirliği içinde bulunmaları gereken bu üçlü grubun konuya ilişkin görüş ve tutumları alanyazında önemli bulunmaktadır. Bu çalışmanın amacı, ebeveynlerin, öğretmenlerin ve DKT’lerin dil ve konuşma bozuklukları alanındaki sorumluluk ve rollerini nasıl algıladıklarını, dil ve konuşma bozukluğu olan çocuğun akademik ve sosyal başarısına yönelik tutumlarını, dil ve konuşma bozukluklarının nedenleri ve terapisine yönelik düşüncelerini betimlemektir. Çalışmaya 37 aile bireyi, 46 öğretmen ve 35 DKT katılmıştır. Anket yoluyla elde edilen veriler her grubun konuya ilişkin bilgisini ortaya koymak için karşılaştırılmıştır. Dil ve konuşma bozukluğu olan çocukların akademik/sosyal başarılarına yönelik tutumlarında diğer katılımcı gruplara göre öğretmenlerin, çocukların terapi gereksinimlerine yönelik tutumlarında ise ailelerin daha kararsız tutumlar geliştirdikleri dikkat çekmektedir.Dil ve konuşma bozukluklarının nedenleri ve terapi eksikliklerine yönelik bilgilerinde grupların öncelikli sıralamalarının farklılaştığı görülmüştür

  13. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2016-12-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  14. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2017-12-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  15. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2018-04-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  16. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2017-08-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  17. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2017-04-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  18. What remains of the Arrow oil?

    International Nuclear Information System (INIS)

    Sergy, G.; Owens, E.

    1993-01-01

    In February 1970, the tanker Arrow became grounded 6.5 km off the north shore of Chedabucto Bay, Nova Scotia, and nearly 72,000 bbl of Bunker C fuel oil were released from the vessel during its subsequent breakup and sinking. The oil was washed ashore in various degrees over an estimated 305 km of the bay's 604-km shoreline, of which only 48 km were cleaned. In addition, the tanker Kurdistan broke in two in pack ice in March 1979 in the Cabot Strait area, spilling ca 54,000 bbl of Bunker C, some of which was later found at 16 locations along the northeast and east shorelines of Chedabucto Bay. In summer 1992, a systematic ground survey of the bay's shorelines was conducted using Environment Canada Shoreline Cleanup Assessment Team (SCAT) procedures. Standard observations were made of oil distribution and width, thickness, and character of the oil residues in 419 coastal segments. Results from the survey are summarized. Oil was found to be present on 13.3 km of the shoreline, with heavy oiling restricted to 1.3 km primarily in the areas of Black Duck Cove and Lennox Passage. Some of this residual oil was identified as coming from the Arrow. Natural weathering processes account for removal of most of the spilled oil from the bay. Oil remaining on the shore was found in areas outside of the zone of physical wave action, in areas of nearshore mixing where fine sediments are not present to weather the oil through biophysical processes, or in crusts formed by oil weathered on the surface. The systematic description of oiled shorelines using the SCAT methodology proved very successful, even for such an old spill. 6 refs

  19. Ghost Remains After Black Hole Eruption

    Science.gov (United States)

    2009-05-01

    NASA's Chandra X-ray Observatory has found a cosmic "ghost" lurking around a distant supermassive black hole. This is the first detection of such a high-energy apparition, and scientists think it is evidence of a huge eruption produced by the black hole. This discovery presents astronomers with a valuable opportunity to observe phenomena that occurred when the Universe was very young. The X-ray ghost, so-called because a diffuse X-ray source has remained after other radiation from the outburst has died away, is in the Chandra Deep Field-North, one of the deepest X-ray images ever taken. The source, a.k.a. HDF 130, is over 10 billion light years away and existed at a time 3 billion years after the Big Bang, when galaxies and black holes were forming at a high rate. "We'd seen this fuzzy object a few years ago, but didn't realize until now that we were seeing a ghost", said Andy Fabian of the Cambridge University in the United Kingdom. "It's not out there to haunt us, rather it's telling us something - in this case what was happening in this galaxy billions of year ago." Fabian and colleagues think the X-ray glow from HDF 130 is evidence for a powerful outburst from its central black hole in the form of jets of energetic particles traveling at almost the speed of light. When the eruption was ongoing, it produced prodigious amounts of radio and X-radiation, but after several million years, the radio signal faded from view as the electrons radiated away their energy. HDF 130 Chandra X-ray Image of HDF 130 However, less energetic electrons can still produce X-rays by interacting with the pervasive sea of photons remaining from the Big Bang - the cosmic background radiation. Collisions between these electrons and the background photons can impart enough energy to the photons to boost them into the X-ray energy band. This process produces an extended X-ray source that lasts for another 30 million years or so. "This ghost tells us about the black hole's eruption long after

  20. Anonimlik deneyimi ve sosyal medya etkisi

    OpenAIRE

    Aslan, M.Gökhan

    2012-01-01

    116 pages Anonimlik bir kelime olarak çağrıştırdığı ilk anlamlarının ötesinde çok katmanlı bir deneyimi temsil etmektedir. Bu tez çalışmasında amaçlanan, ilk adımda anonimliği sözlük anlamından itibaren başlayarak kapsamlı bir tanımsal analize tabi tutmaktır. Bu analiz dahilinde anonimliğin nitelikleri ve türleri bir bütün olarak ele alınmaktadır. İkinci adımda ise anonimliğin farklı iletişim biçimlerindeki dönüşümünün, paralel sosyal ve teknolojik değişimlerle beraber izi sürülerek son ba...

  1. Neutron activation analysis of the prehistoric and ancient bone remains

    International Nuclear Information System (INIS)

    Vasidov, A.; Osinskaya, N.S.; Khatamov, Sh.; Rakhmanova, T.; Akhmadshaev, A.Sh.

    2006-01-01

    Full text: In the work results of the instrumental neutron activation analysis (INAA) of prehistoric bone remains of dinosaurs and ancient bones of bear, archantrop found out on the territory of Uzbekistan are presents. A bone of dinosaur from Mongolia, standard a bone of the person and soils taken from a surface and from of the femoral joint of a dinosaur were also subject to INAA. The INAA method determines of contents of about 30 elements in bones and soils in an interval 0.043-3600 mg / kg. Among found elements Ca (46 %), Sc, Cr, Fe (up to 2.2 g/kg), Ni, Zn, Sr (up to 3.6 g/kg), Sb, Ba, Sb and some others are mainly found in bones. The contents of some elements in bones of dinosaurs reach very high values 280-3200 mg / kg, and are mainly lanthanides La, Ce, Nd, Sm, Eu, Tb, Yb and Lu. In our opinion, lanthanides and some other elements, like As, Br, and Mo in bones were formed as a result of fission of uranium and transuranium elements. Because content of uranium in bones of dinosaurs is very high, up to 180 mg / kg, and those of thorium is 20 mg/ kg. However U and Th in soils are 4.8 mg/kg and 3.7 mg / kg, respectively. The content of uranium in bones of the archantrop is 1.53 mg / kg, while U in standard bone of the human is less than 0,016 mg/kg. (author)

  2. BProVe: Tool support for business process verification

    DEFF Research Database (Denmark)

    Corradini, Flavio; Fornari, Fabrizio; Polini, Andrea

    2017-01-01

    This demo introduces BProVe, a tool supporting automated verification of Business Process models. BProVe analysis is based on a formal operational semantics defined for the BPMN 2.0 modelling language, and is provided as a freely accessible service that uses open standard formats as input data...

  3. Corium Spreading Over Concrete: The Vulcano VE-U7 and VE-U8 Tests

    International Nuclear Information System (INIS)

    Journeau, Christophe; Boccaccio, Eric; Fouquart, Pascal; Jegou, Claude; Piluso, Pascal

    2002-01-01

    Two experiments have been performed in the VULCANO facility in which prototypic corium has been spread over concrete. In the VE-U7 test, a mixture representative of what can be expected at the opening of EPR reactor-pit gate has been spread on siliceous concrete and on a reference channel in inert refractory ceramic. The spreading progression was not much affected by the presence of concrete and sparging gases. In the VE-U8 test, a UO 2 -ZrO 2 mixture, prototypic of in-vessel corium, has been spread over a lime-siliceous concrete. Although residual power was not simulated in this experiment, up to 2 cm of concrete have been eroded during the test. Results in terms of spreading behaviour, effects of gases, concrete erosion and thermal attack are presented and discussed. (authors)

  4. Turist Motivasyonunda Mahalli Kültür ve Etkisi ve Apart Ziyaretlerinde Turist Memnuniyeti

    Directory of Open Access Journals (Sweden)

    Nguyen Quang VINH

    2013-09-01

    Full Text Available Bu çalışma, apart turizm hizmet sektöründe stratejik pazarlama kararının tesis edilmesi anlayışını sağlamak için turizm planlamacılarına ve turizmcilere yardım etmeyi amaçlamaktadır. Ampirik analiz için Duonglam Eski Köyü’nün apart hizmetinden faydalanmış 150 uluslararası ziyaretçinin oluşturduğu datalar kullanılmıştır. Turist motivasyonu ve nihai varış noktası sadakatindeki memnuniyet arasındaki hipotezleri test etmek amacıyla regresyon yöntemi benimsenmiştir. Bu çalışma Duonglam köyündeki iklim şartları, nihai varış noktasına ulaşım kolaylığı, konaklama kalitesi, doğal güzellikler ve hijyen şartlarının turist memnuniyeti üzerinde önemli etkileri olduğu sonucunu çıkarmıştır. Diğer taraftan da bu sonuçlar Duonglam Eski Köyü’nün kültürel aktiviteleri ve turizm hizmet sektörü hakkında olumsuz bir kanıyı temsil etmektedir. Ayrıca çalışmada, araştırmanın sınırı ve turizm sektörü çalışanları için elde edilen bulguların sonuçları tartışılmıştır.

  5. Yerelden Evrensele Japon Anime ve Manga Sanatı

    OpenAIRE

    TAŞ ALİCENAP, Çiğdem

    2014-01-01

    Anime ve manga kültürü Uzakdoğu çizgi roman sanatının yoğun üretimi, tarih, din, kültür ve felsefenin konulara yansıması ve Batı çizgi film ve çizgi romanlarından ayrılan farklı tarzlarıyla araştırılması ve öğrenilmesi gereken değerler içermektedir. Japonya’ da çizgi film sanatının Batı’ daki Disney gibi bir endüstrinin dışında bu denli özgün ve başarılı örnekleri elbette o sanatçıların yetiştiği kültürün, tarihin, sanatın ve felsefi değerlerin olduğu kadar eski...

  6. Uygulamalı Bilimler ve Mühendislik

    Directory of Open Access Journals (Sweden)

    Recep BAKIŞ

    2011-12-01

    Full Text Available Bu makalede, sanayi, tarım ve evsel atık sularla yoğun bir şekilde kirletilen Porsuk çayı ve havzasındaki yüzeysel ve yeraltı suyu kirlilik düzeyi araştırılmıştır. Bu amaçla, Porsuk çayı boyunca ve havza içinden 20 istasyon seçilerek, 2 yıl boyunca mevsimsel yüzeysel ve yeraltı su örnekleri alınmıştır. Yüzeysel sularda toplam 18, yeraltı sularında ise toplam 15 parametre analiz edilmiştir. Elde edilen sonuçlar, mevsimsel değişikliklerin sebebine bakılmaksızın, Su Kirliliği Kontrolü Yönetmeliği Kıta İçi Su Kaynakları sınıfları ve uluslar arası standartlarla karşılaştırılmıştır. Porsuk çayı ve havzasındaki hem yüzey suyunun hem de yeraltı suyunun IV. Kalite su sınıfında olduğu tespit edilmiştir

  7. Association between auditory P300, psychopathology, and memory function in drug-naïve schizophrenia

    Directory of Open Access Journals (Sweden)

    Wei-Hung Chang

    2014-03-01

    Full Text Available The aim of this study was to explore memory deficits and psychopathology and their relationships with P300 in drug-naïve patients with schizophrenia. The Positive and Negative Syndrome Scale (PANSS and the Wechsler Memory Scale—Revised were administered. Auditory event-related potentials elicited by an oddball paradigm were obtained. After controlling for age, sex, the results showed a statistically significant negative correlation between the total PANSS score and P300 amplitude at the parietal position (r = −0.66, p < 0.05. Moreover, visual memory was significantly positively correlated with P300 amplitude at the parietal position (r = 0.67, p < 0.05. After controlling for the duration of illness, the above correlations remained statistically significant. The correlation between P300 and the severity of psychopathology was reconfirmed in drug-naïve patients with schizophrenia. A possible contribution of memory decompensation in P300 among drug-naïve patients with schizophrenia may be considered, and the compensatory or Default Model Network might be a possible explanation of this association.

  8. Analyzing Program Termination and Complexity Automatically with AProVE

    DEFF Research Database (Denmark)

    Giesl, Jürgen; Aschermann, Cornelius; Brockschmidt, Marc

    2017-01-01

    In this system description, we present the tool AProVE for automatic termination and complexity proofs of Java, C, Haskell, Prolog, and rewrite systems. In addition to classical term rewrite systems (TRSs), AProVE also supports rewrite systems containing built-in integers (int-TRSs). To analyze...... programs in high-level languages, AProVE automatically converts them to (int-)TRSs. Then, a wide range of techniques is employed to prove termination and to infer complexity bounds for the resulting rewrite systems. The generated proofs can be exported to check their correctness using automatic certifiers...

  9. Bulut Bilişim ve Mali Etkileri: Bulutta Vergi=Cloud Computing And Its Financial Effects: Tax On Cloud

    Directory of Open Access Journals (Sweden)

    Metin TURAN

    2014-12-01

    Full Text Available Bulut bilişim genel olarak yazılımın, altyapının ve platformun hizmet olarak sunulması ve bu bilişim kaynaklarına çoğunlukla İnternet üzerinden yerden bağımsız erişim sağlanmasıdır. Bulut bilişim İnternetin gelişmesi ve kullanımının artması ile yaygınlaşmıştır. Bu çalışmanın amacı, kullanılan ya da hizmete sunulan bulut bilişim hizmetleri için oluşan vergi konusunu analiz etmektir. Çalışmada, kurum ve kuruluşların bulut bilişim hizmetleri dolayısıyla hangi tür vergilere tabi oldukları incelenmiş ve ortaya çıkan sorunlar belirtilerek çözüm önerileri sunulmuştur. Bu kapsamda, vergi kanunları ve ikincil mevzuat içerik analizi yöntemi ile incelenmiş ve Türkiye’de vergi mevzuatında doğrudan ve dolaylı olarak bulut bilişime yönelik çeşitli hükümlerin bulunduğu görülmüştür./In general, cloud computing is that software, platform and infrastructure as a service become available, and provide location independent access to these computing resources from anywhere, mostly via the Internet. Cloud computing has become widespread with development of Internet and its increasing use. This study aims to analyze the tax issue arising from cloud computing consumed or provided. In the study, institutions and organizations were examined due to cloud computing to which kind of tax they are subject and solutions recommendations were presented by indicating issues arised. In this context, the tax laws and secondary legislation were examined by content analysis and, it was seen that in Turkey, there were directly and indirectly some provisions in Tax legislation for cloud computing.

  10. Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells.

    Science.gov (United States)

    Xu, Zhuojin; Robitaille, Aaron M; Berndt, Jason D; Davidson, Kathryn C; Fischer, Karin A; Mathieu, Julie; Potter, Jennifer C; Ruohola-Baker, Hannele; Moon, Randall T

    2016-10-18

    In both mice and humans, pluripotent stem cells (PSCs) exist in at least two distinct states of pluripotency, known as the naïve and primed states. Our understanding of the intrinsic and extrinsic factors that enable PSCs to self-renew and to transition between different pluripotent states is important for understanding early development. In mouse embryonic stem cells (mESCs), Wnt proteins stimulate mESC self-renewal and support the naïve state. In human embryonic stem cells (hESCs), Wnt/β-catenin signaling is active in naïve-state hESCs and is reduced or absent in primed-state hESCs. However, the role of Wnt/β-catenin signaling in naïve hESCs remains largely unknown. Here, we demonstrate that inhibition of the secretion of Wnts or inhibition of the stabilization of β-catenin in naïve hESCs reduces cell proliferation and colony formation. Moreover, we show that addition of recombinant Wnt3a partially rescues cell proliferation in naïve hESCs caused by inhibition of Wnt secretion. Notably, inhibition of Wnt/β-catenin signaling in naïve hESCs did not cause differentiation. Instead, it induced primed hESC-like proteomic and metabolic profiles. Thus, our results suggest that naïve hESCs secrete Wnts that activate autocrine or paracrine Wnt/β-catenin signaling to promote efficient self-renewal and inhibit the transition to the primed state.

  11. CELESTINA: CALISTO VE MELİBEA’NIN TRAJIKOMEDYASI’NDA ORTAÇAĞ VE RÖNESANS ARASINDA KALMIŞ BİREY VE KADIN

    Directory of Open Access Journals (Sweden)

    Nur Gülümser İLKER

    2017-06-01

    Full Text Available İspanyol Edebiyatının Ortaçağ toplumu ve bireyi arasındaki çatışmayı ele almasıyla en önemli eserlerinden biri olan Celestina: Calisto ve Melibea’nın Trajikomedyası, Rönesans’a dönmüş yüzüyle de önem kazanmaktadır. Yazar Fernando de Rojas’ın ustalıkla ve incelikle yarattığı karakterler vasıtasıyla, dönemin birey algısına odaklanırken, toplumun normlarının bireyler üzerindeki üstünlüğüne tanık oluruz. Aynı zamanda kadına karşı olan bakış açısının da vurgulandığı eserde, evrensel konular gün yüzüne çıkarken, insan, doğasıyla ve içgüdüleriyle işlenerek okuyucuya sunulur. Eserde genç, tutkularının kölesi olmuş Calisto ve saf, geleneklerine bağlı Melibea’nın aşkıyla ve de yaşlı büyücü Celestina’nın tamahkârlığıyla insani duyguların aşırıya kaçması eleştirilir. Topluma uygun olmayan eylemler sonucunda cezalandırılan karakterleriyle eser, didaktik bir metin olma özelliği taşımaktadır. Çalışmanın konusu olarak sözü geçen eserdeki birey ve kadın, Ortaçağ ve Rönesans arasında kalmış olarak ele alınacak ve incelenecektir.

  12. "Recent" macrofossil remains from the Lomonosov Ridge, central Arctic Ocean

    Science.gov (United States)

    Le Duc, Cynthia; de Vernal, Anne; Archambault, Philippe; Brice, Camille; Roberge, Philippe

    2016-04-01

    The examination of surface sediment samples collected from 17 sites along the Lomonosov Ridge at water depths ranging from 737 to 3339 meters during Polarstern Expedition PS87 in 2014 (Stein, 2015), indicates a rich biogenic content almost exclusively dominated by calcareous remains. Amongst biogenic remains, microfossils (planktic and benthic foraminifers, pteropods, ostracods, etc.) dominate but millimetric to centrimetric macrofossils occurred frequently at the surface of the sediment. The macrofossil remains consist of a large variety of taxa, including gastropods, bivalvia, polychaete tubes, scaphopods, echinoderm plates and spines, and fish otoliths. Among the Bivalvia, the most abundant taxa are Portlandia arctica, Hyalopecten frigidus, Cuspidaria glacilis, Policordia densicostata, Bathyarca spp., and Yoldiella spp. Whereas a few specimens are well preserved and apparently pristine, most mollusk shells displayed extensive alteration features. Moreover, most shells were covered by millimeter scale tubes of the serpulid polychaete Spirorbis sp. suggesting transport from low intertidal or subtidal zone. Both the ecological affinity and known geographic distribution of identified bivalvia as named above support the hypothesis of transportation rather than local development. In addition to mollusk shells, more than a hundred fish otoliths were recovered in surface sediments. The otoliths mostly belong to the Gadidae family. Most of them are well preserved and without serpulid tubes attached to their surface, suggesting a local/regional origin, unlike the shell remains. Although recovered at the surface, the macrofaunal assemblages of the Lomonosov Ridge do not necessarily represent the "modern" environments as they may result from reworking and because their occurrence at the surface of the sediment may also be due to winnowing of finer particles. Although the shells were not dated, we suspect that their actual ages may range from modern to several thousands of

  13. Gravitational waves in Einstein-æther and generalized TeVeS theory after GW170817

    Science.gov (United States)

    Gong, Yungui; Hou, Shaoqi; Liang, Dicong; Papantonopoulos, Eleftherios

    2018-04-01

    In this work we discuss the polarization contents of Einstein-æther theory and the generalized tensor-vector-scalar (TeVeS) theory, as both theories have a normalized timelike vector field. We derive the linearized equations of motion around the flat spacetime background using the gauge-invariant variables to easily separate physical degrees of freedom. We find the plane wave solutions and identify the polarizations by examining the geodesic deviation equations. We find that there are five polarizations in Einstein-æther theory and six polarizations in the generalized TeVeS theory. In particular, the transverse breathing mode is mixed with the pure longitudinal mode. We also discuss the experimental tests of the extra polarizations in Einstein-æther theory using pulsar timing arrays combined with the gravitational-wave speed bound derived from the observations on GW 170817 and GRB 170817A. It turns out that it might be difficult to use pulsar timing arrays to distinguish different polarizations in Einstein-æther theory. The same speed bound also forces one of the propagating modes in the generalized TeVeS theory to travel much faster than the speed of light. Since the strong coupling problem does not exist in some parameter subspaces, the generalized TeVeS theory is excluded in these parameter subspaces.

  14. KARHUNEN-LOÈVE Basis Functions of Kolmogorov Turbulence in the Sphere

    Science.gov (United States)

    Mathar, Richard J.

    In support of modeling atmospheric turbulence, the statistically independent Karhunen-Loève modes of refractive indices with isotropic Kolmogorov spectrum of the covariance are calculated inside a sphere of fixed radius, rendered as series of 3D Zernike functions. Many of the symmetry arguments of the well-known associated 2D problem for the circular input pupil remain valid. The technique of efficient diagonalization of the eigenvalue problem in wavenumber space is founded on the Fourier representation of the 3D Zernike basis, and extensible to the von-Kármán power spectrum.

  15. Vişne ve Nar Suyu ve Konsantratlarında Antosiyaninlerin Degradasyonu

    Directory of Open Access Journals (Sweden)

    Narmela Asafı

    2015-02-01

    Full Text Available Nar ve vişne suyu konsantratlarında antosiyaninlerin parçalanması üzerine sıcaklığın etkisi incelenmiştir. 70°Bx'lik konsantratlardan 45°Bx ve 15° Bx lik örnekler hazırlanarak -18°C, 5°C, 20°C ve 37°C depolanmıştır. Depolanma süresince, sıcaklık dercesine bağlı olarak değişik aralıklarla alman örneklerde antosiyanin kaybı saptanarak parçalanma hızı incelenmiştir. Elde edilen bulgulara göre antosiyaninlerin parçalanma­sı birinci dereceden bir reaksiyon kinetiğine göre gelişmektedir. Tüm örneklerde beklendiği gibi sıcaklık derecesi yükseldikçe antosiyaninlerin degradasyon hızları artmaktadır. Örneğin 15° Bx'lik vişne suyunda -18°C'de hız konsantı k=0.534 x 10-3 gün-1 olduğu halde, 37°C'de k= 184 x 10-3 gün-1 'e yükselmiştir. Aynı şekilde 15° Bx'lik vişne suyunda -18°C'de hız konstantı k= 0.203 x 10-3 gün-1 olduğu halde 37°C'de k= 94 x10-3 gün-1'e yükselmiştir. Ayrıca reaksiyonun sıcaklığa bağımlılığı, Arrhenius eşitliğinden yararlanarak açıklanmaya çalışılmıştır. Nar suyu ve konsantratlannda antosiyaninlerin degradasyon hızı, vişne suyu ve konsantratlarında olduğundan daha yüksektir. Böylece nar suyu ve konsantratlarında depolama süresince sıcaklığa bağlı olarak hızla renk kaybı oluşmaktadır. Ayrıca doğal briksindeki vişne suyunda antosiyaninler, konsantratlarda olduğundan daha stabil olduğu halde nar suyunda bunun aksine konsantratlardaki antosiyaninlerin daha stabil ol­duğu anlaşılmaktadır.

  16. Tanenler ve Hayvan Besleme Üzerine Etkileri

    Directory of Open Access Journals (Sweden)

    Esin Ünver

    2014-06-01

    Full Text Available Tanenler; bitkilerin yapısında doğal olarak bulunan, kendilerini patojen mikroorganizmalara ve virüslere karşı korumak için ürettikleri fenolik bileşiklerdir. Hayvan besleme açısından ise tanenler; hayvanın türü, fizyolojik durumu, tanenin yapısı ve miktarına bağlı olarak olumlu ve olumsuz etkilere sebep olabilmektedirler. Bu çalışmanın amacı; tanenler, etkileri ve hayvan beslemede kullanımları ile ilgili bir derleme sunmaktır.

  17. Feminist Sanatta Beden ve Yabancılaşma

    OpenAIRE

    Alp, Kafiye Özlem

    2015-01-01

    Feminizm, eril bir toplumda kadının, eşit hak ve özgürlüklere sahip olma gerekçelerine dayalı bir mücadele alanı olarak tanımlanabilir. Feminizmin, kamusal ve özel alanda kadın ayrımcılığına karşı başkaldırısı, insanın kendi emeğine ve kendi bedenine olan yabancılaşmasının bir sonucudur. Bu bakımdan feminizm, tüm tarihi boyunca toplumsal, felsefi, cinsel ve psikanalitik yabancılaşma kavramlarıyla yakın ilgi içinde olmuştur. Feminist sanat pratikleri; feminist kuramlar, toplumsal dinamikler...

  18. Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

    Science.gov (United States)

    Broermann, Andre; Winderlich, Mark; Block, Helena; Frye, Maike; Rossaint, Jan; Zarbock, Alexander; Cagna, Giuseppe; Linnepe, Ruth; Schulte, Dörte; Nottebaum, Astrid Fee

    2011-01-01

    We have recently shown that vascular endothelial protein tyrosine phosphatase (VE-PTP), an endothelial membrane protein, associates with VE-cadherin and is required for optimal VE-cadherin function and endothelial cell contact integrity. The dissociation of VE-PTP from VE-cadherin is triggered by vascular endothelial growth factor (VEGF) and by the binding of leukocytes to endothelial cells in vitro, suggesting that this dissociation is a prerequisite for the destabilization of endothelial cell contacts. Here, we show that VE-cadherin/VE-PTP dissociation also occurs in vivo in response to LPS stimulation of the lung or systemic VEGF stimulation. To show that this dissociation is indeed necessary in vivo for leukocyte extravasation and VEGF-induced vascular permeability, we generated knock-in mice expressing the fusion proteins VE-cadherin-FK 506 binding protein and VE-PTP-FRB* under the control of the endogenous VE-cadherin promoter, thus replacing endogenous VE-cadherin. The additional domains in both fusion proteins allow the heterodimeric complex to be stabilized by a chemical compound (rapalog). We found that intravenous application of the rapalog strongly inhibited VEGF-induced (skin) and LPS-induced (lung) vascular permeability and inhibited neutrophil extravasation in the IL-1β inflamed cremaster and the LPS-inflamed lung. We conclude that the dissociation of VE-PTP from VE-cadherin is indeed required in vivo for the opening of endothelial cell contacts during induction of vascular permeability and leukocyte extravasation. PMID:22025303

  19. Banque Cantonale de Genève

    CERN Multimedia

    Banque Cantonale de Genève

    2011-01-01

    7e Salon Immobilier BCGE le samedi 3 septembre 2011, de 8 h 30 à 13 h 00, au Centre de formation de Conches À cette occasion, les meilleurs spécialistes professionnels genevois de l’immobilier seront réunis en un seul et même lieu. Si vous le souhaitez, un conseiller spécialisé dans les financements hypothécaires évaluera vos possibilités d’investissement immobilier adaptées à votre situation personnelle. En parallèle, les plus importantes régies immobilières de Genève seront à votre disposition pour vous présenter leurs offres actuelles, ainsi que les projets immobiliers futurs et discuter avec vous de la meilleure stratégie à adopter pour trouver l’objet de vos rêves. De plus, vous aurez la possibilité...

  20. Characterizing vertical heterogeneity of permafrost soils in support of ABoVE radar retrievals

    Science.gov (United States)

    Tabatabaeenejad, A.; Chen, R. H.; Silva, A.; Schaefer, K. M.; Moghaddam, M.

    2017-12-01

    Permafrost-affected soils, including the top active layer and underlying permafrost, have unique seasonal variations in terms of soil temperature, soil moisture, and freeze/thaw-state profiles. The presence of a perennially frozen and impermeable substrate maintains the required temperature gradient for the descending thawing front, and causes meltwater to accumulate and form the saturated zone in the active layer. Radar backscattering measurements are sensitive to dielectric properties of subsurface soils, which are strongly correlated with unfrozen water content and soil texture/composition. To enable accurate radar retrievals, we need to properly characterize soil profile heterogeneity, which can be modeled with layered soil or depth-dependent functions. To this end, we first cross compare the measured radar backscatter and model-predicted radar backscatter using in-situ dielectric profile measurements as well as mathematical or hydrologic-based profile functions. Since radar signal's backscatter has limited penetration, to fully capture the true heterogeneity profile, we determine the optimal profile function by minimizing the error between predicted and measured radar backscatter signals as well as between in-situ and fitted profiles. The in-situ soil profile data (temperature, dielectric constant, unfrozen water content, organic/mineral soils) are collected from the Soil Moisture Sensing Controller And oPtimal Estimator (SoilSCAPE) sensor networks and from the Arctic-Boreal Vulnerability Experiment (ABoVE) field campaign in August 2017 (concurrent with the ABoVE August flights over Alaska North Slope) while the radar data are acquired by NASA's P-band AirMOSS and L-band UAVSAR as part of the ABoVE airborne campaign. The retrieval results using our new heterogeneity model will be compared with the results from retrievals that model soil as a layered medium. This analysis can advance the accuracy of retrieval of active layer properties using low-frequency SAR

  1. Tom Stoppard'ın Rosencrantz ve Guildenstern Öldüler Adlı Oyununda Mizah ve Kader

    OpenAIRE

    Erkan, Ayça Ülker

    2016-01-01

    Bu çalışmanın amacı karakterlerin kimlik arayışından kaynaklanan fiziksel mizahı tartışmak ve oyundaki ölüm/şans/kader/gerçeklik/yanılsama gibi temaların Rosencrantz ve Guildenstern’nin varoluşçu hayatlarında nasıl işlediğini göstermektir. Mizah, bu trajikomedinin analiz edilmesinde önemli bir rol oynar. Absürd Tiyatro, insanlık durumundaki saçmalığı ifade eder, rasyonel aygıtların kullanımını terk eder, insanın trajik kaybolmuşluk duygusunu yansıtır ve insanlık durumu olan hayat ve ölümle il...

  2. Factors influencing home care nurse intention to remain employed.

    Science.gov (United States)

    Tourangeau, Ann; Patterson, Erin; Rowe, Alissa; Saari, Margaret; Thomson, Heather; MacDonald, Geraldine; Cranley, Lisa; Squires, Mae

    2014-11-01

    To identify factors affecting Canadian home care nurse intention to remain employed (ITR). In developed nations, healthcare continues to shift into community settings. Although considerable research exists on examining nurse ITR in hospitals, similar research related to nurses employed in home care is limited. In the face of a global nursing shortage, it is important to understand the factors influencing nurse ITR across healthcare sectors. A qualitative exploratory descriptive design was used. Focus groups were conducted with home care nurses. Data were analysed using qualitative content analysis. Six categories of influencing factors were identified by home care nurses as affecting ITR: job characteristics; work structures; relationships/communication; work environment; nurse responses to work; and employment conditions. Findings suggest the following factors influence home care nurse ITR: having autonomy; flexible scheduling; reasonable and varied workloads; supportive work relationships; and receiving adequate pay and benefits. Home care nurses did not identify job satisfaction as a single concept influencing ITR. Home care nursing management should support nurse autonomy, allow flexible scheduling, promote reasonable workloads and create opportunities for team building that strengthen supportive relationships among home care nurses and other health team members. © 2013 John Wiley & Sons Ltd.

  3. Local Content

    CSIR Research Space (South Africa)

    Gibberd, Jeremy

    2016-10-01

    Full Text Available Local content refers to materials and products made in a country as opposed those that are imported. There is an increasing interest in the concept of local content as a means of supporting local economies and providing jobs (Belderbos & Sleuwaegen...

  4. Silah, Tasarım ve Kalashnikov Ak-47

    OpenAIRE

    Güneş, Serkan

    2015-01-01

    Silah olgusu insanlığın varoluşundan bu yana saldırmanın ve korunmanın dolayısıyla;yaşamayı sürdürmenin temel araçlarından birisi olarak karşımıza çıkıyor. Medeniyetkavramı ve devletler silah üzerine inşa ediliyor, bekası silah ile korunuyor ve gereklikoşullar oluştuğunda silah vasıtası ile yayılıyor. Güvenlik, huzur ve tehditler için silahlartasarlanıyor, üretiliyor. Silah tasarımı, bekli de insanlık tarihinin en istikrarlı ve en uzuntasarım süreci. Milyonlarca yaratıcı beyin aynı anda öteki...

  5. Domates Pulpu ve Salçasında Viskozite (Konsistens ve Renk Üzerine Proses Koşullarının Etkisi

    Directory of Open Access Journals (Sweden)

    Aziz Ekşi

    2015-02-01

    Full Text Available Kıvam ve renk, domates pulpu ve salçada kaliteyi belirleyen ve ticarette üzerinde en çok durulan iki önemli etkendir. Domates salçasında renk ve kıvam ile hammaddenin durumu arasında yakın bir ilişki bulunduğu bilinmektedir. Ancak her iki kalite öğesini ve özellikle kıvamı, hammadde olduğu kadar, proses koşulları da etkilemektedir.

  6. NATURALIZATION AND SEYHULISLAM YAHYA MAHALLÎLEŞME VE ŞEYHÜLİSLAM YAHYA

    Directory of Open Access Journals (Sweden)

    Hakan YEKBAŞ

    2009-08-01

    Full Text Available Local factors which are important source of our classical literature in terms of contents were used more characteristicly by some classic poets. One of these poets, Şeyhülislam Yahya, although he has an identity of Muslim preacher, employed the delight and entertainment of life with elegant Turkish of Istanbul. Above all in his ghazals, he is highly successful in expressing the coloured stage chosen in daily life by using elegant Turkish, idioms proverbs, and folk sayings. Understanding of this art is effective in his being one of the most important represantative of naturalization at XVII. century. Klasik edebiyatımızın dil ve muhteva bakımından önemli kaynaklarından olan mahallî unsurlar, bazı klasik şairlerimiz tarafından daha belirgin bir şekilde kullanılmıştır.. Bu şâirlerden biri olan Şeyhülislam Yahya, bir din adamı kimliğine sahip olmasına rağmen hayatın zevk ve eğlencelerini sade İstanbul Türkçesini kullanarak şiirlerinde işlemiştir. Özellikle gazellerinde kullandığı sade Türkçesi, deyimleri, atasözleri ve halk deyişleri vasıtasıyla günlük hayatın içinden seçtiği canlı sahneleri anlatmada çok başarılıdır. Bu sanat anlayışı, onun mahallîleşmenin XVII. yüzyıldaki en önemli temsilcilerinden biri olmasına neden olmuştur.

  7. Kuramsal ve İşlevsel Dil Öğretiminde Tiyatronun Rolü ve Önemi

    Directory of Open Access Journals (Sweden)

    Gıyasettin AYTAŞ

    2017-10-01

    Full Text Available Tiyatro bir sanat faaliyeti olmanın yanında etkili bir iletişim aracıdır. En eski dönemlerden bu yana, hatta insanlığın varlığından itibaren tiyatrodan ve onun etkililiğinden söz etmek olasıdır. Dil edinim süreçleri ile ilgili görüşler birbirinden farklı olmakla birlikte, dilin kullanımında en temel gösterge iletişim ihtiyacıdır. Bununla birlikte dil aynı zamanda bir temsil göstergesidir. Onun aracılığı ile aidiyet ve mensubiyetler hakkında hüküm verilir. Bireyin sosyal ve siyasal özelliklerinin yanında, karakteristik özelliklerini de kullandığı dil aracılığı ile tespit edebilmekteyiz. Tiyatro bu farklılıkların her birini bir arada sergileyen ve somut bir göstergeye dönüştüren bir araç olarak karşımıza çıkmaktadır. Tiyatro yaşanmışlıkları bir araya getirerek iletişim çeşitliliğini ve zenginliğini ortaya koyar. Hayatın hem var olanını hem de olması gerekenlerini birlikte sunar. Her ne kadar bir durum veya olay sonsuz olarak değerlendirilmesi mümkün değilse de tiyatro bu mümkün olmayana varsayımlar açısından yaklaşır. İnsan davranışlarının bilinçli ve bilinçsiz olmak üzere iki göstergesi bulunmaktadır. Bu iki durumla ilgili iletişim yeterliliklerini ve farklılıklarını tiyatro aracılığı ile birlikte görebiliriz. Güzel sanatların hemen tamamını bir arada ve birlikte içinde barındıran tiyatro, bütün dil aşamaların birlikte ve bir arada sunar. Hem iç hem de dış konuşmanın bütün inceliklerini birlikte sunan ve bu özelliği ile karşılıklı ifade çeşitliliğini tiyatro birlikte sunar. İletişim ve dil ediniminde tiyatronun önemini ve gerekliliğini anlamak ve sorgulamak için tiyatronun işlevsel özelliğinden bütün ayrıntıları ile yararlanmak kaçınılmazdır.

  8. Unabomber: “Sanayi Toplumu ve Geleceği”

    OpenAIRE

    URAL, Mustafa Nuri; TÜRKAL, İhsan

    2015-01-01

    Ancak çok az şey toplumu Sanayi Devriminin değiştirdiği kadar köklü ve derinden değiştirmiştir. Hiç kimse isteyerek modern hayatın nimetlerinden vazgeçmeye gönüllü gözükmüyor. Ama giderek artan problemler birçok düşünce insanı tarafından yüksek sesle dile getiriliyor. Theodore John Kaczynski kitabında modern toplumun sorunlarını, teknolojinin bu bağlamdaki etkisini, çözümleri ve devrimin önündeki tehlikeleri analitik bir biçimde inceliyor. Gerek yöntemiyle gerek oluşum süreciyle ve içeriğiyle...

  9. Addison hastalığı ve gebelik

    OpenAIRE

    Bayrak, Z; Turan, V; Demirtaş, G; Erdoğan, M; Aşkar, N

    2011-01-01

    Primer adrenal yetmezlik nadir görülen bir endokrinolojik hastalıktır. Çoğu idiopatiktir. Tip 1 diabetes mellitus, hipertiroidizm, hipotiroidizm, pernisiyöz anemi gibi otoimmun hastalıklarla ilişkilidir. Yirmi sekiz yaşında 18 yıldır Addison hastalığı nedeni ile tedavi gören ve gebelik istemi olan olguyu gebeliğin ilk haftalarından doğuma ve puerperal döneme kadar takip ettik. Endokrinoloji kliniği ile birlikte takip ettiğimiz hastada kortikosteroid tedavisi ile antenatal ve postnatal dönemde...

  10. Kefir ve Sağlık

    OpenAIRE

    DAYISOYLU, Kenan Sinan; KÖROĞLU, Özge; BAKIR, Esra; ULUDAĞ, Günsel; KÖROĞLU, Sedat

    2015-01-01

    Özet: Son yıllarda toplumlar beslenme konusunda giderek daha bilinçli hale gelmektedir. Beslenme konusunda temel talep olan sağlıklı ve güvenli gıdalar tüketebilme isteğinin yanında; insan sağlığına ek faydalar sağlayan, hastalıklardan koruma potansiyeli olan ve fonksiyonel gıda olarak adlandırılan ürünlere ulaşma isteği de giderek artmaktadır. Kefir, fonksiyonel gıdalardan probiyotikler alt kolunun önemli bir üyesi olup, içeriğinde birçok faydalı maya ve bakteri bulunduran, son yıllarda popü...

  11. VeLoc: Finding Your Car in Indoor Parking Structures

    Directory of Open Access Journals (Sweden)

    Ruipeng Gao

    2018-05-01

    Full Text Available While WiFi-based indoor localization is attractive, there are many indoor places without WiFi coverage with a strong demand for localization capability. This paper describes a system and associated algorithms to address the indoor vehicle localization problem without the installation of additional infrastructure. In this paper, we propose VeLoc, which utilizes the sensor data of smartphones in the vehicle together with the floor map of the parking structure to track the vehicle in real time. VeLoc simultaneously harnesses constraints imposed by the map and environment sensing. All these cues are codified into a novel augmented particle filtering framework to estimate the position of the vehicle. Experimental results show that VeLoc performs well when even the initial position and the initial heading direction of the vehicle are completely unknown.

  12. VeLoc: Finding Your Car in Indoor Parking Structures.

    Science.gov (United States)

    Gao, Ruipeng; He, Fangpu; Li, Teng

    2018-05-02

    While WiFi-based indoor localization is attractive, there are many indoor places without WiFi coverage with a strong demand for localization capability. This paper describes a system and associated algorithms to address the indoor vehicle localization problem without the installation of additional infrastructure. In this paper, we propose VeLoc, which utilizes the sensor data of smartphones in the vehicle together with the floor map of the parking structure to track the vehicle in real time. VeLoc simultaneously harnesses constraints imposed by the map and environment sensing. All these cues are codified into a novel augmented particle filtering framework to estimate the position of the vehicle. Experimental results show that VeLoc performs well when even the initial position and the initial heading direction of the vehicle are completely unknown.

  13. Superior Mezenter Arter Embolisinde Erken Tanı ve Embolektomi

    OpenAIRE

    AYDIN, İbrahim; YÜCEL, Ahmet; PERGEL, Ahmet; KARAKAYA, Ahmet; OĞULLAR, Sabri; ŞAHİN, Dursun; ÖZER, Ender

    2016-01-01

    Akut mezenter arter embolisi, acil girişim gerektiren, nekroz geliştiğinde yaygın ince barsak rezeksiyonu ve sonrasında gelişen kısa barsak sendromu nedeniyle yaşam kalitesini düşüren, morbidite ve mortalitesi oldukça yüksek bir hastalıktır. Multidetektör kontrastlı BT, akut mezenterik embolinin erken tanısında oldukça önemlidir. Biz burada, kontrastlı abdominal BT ile erken tanı ve sonrasında bağırsak rezeksiyonu gerekmeden yalnızca embolektomi yaparak tedavi ettiğimiz olguyu sunmayı amaçlad...

  14. Berkeley 51 Kümesinin Temel ve Astrofiziksel Parametrelerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    İnci Akkaya Oralhan

    2016-10-01

    Full Text Available Galaksimizin birinci çeyreğinde bulunan ve daha önce çok az çalışılmış açık yıldız kümelerinden biri olan Berkeley 51 kümesinin temel astrofiziksel ve yapısal parametreleri CCD UBV(RIC ve 2MASS JHKS verileri kullanılarak elde edilmiştir. Kümeye ait CCD UBV(RIC verileri Meksika’da bulunan San Pedro Martir Ulusal Gözlemevi’nden 84cm’lik teleskop ile alınmıştır. Küme üyeliklerinin belirlenmesinde ise PPMXL kataloğundaki öz hareket verileri kullanılmıştır. Buna küre bu küme için elde edilen limit yarıçap Rlim=2.5 yay dakikası, kızarma E(B-V=0.85±0.05 kadir, E(J-H=0.28±0.02 kadir, uzaklık modülü DM=(m-M0=10.66±0.04 pc, uzaklığı d=1355±27 pc ve logaritmik yaş log(A=9.54±0.03 Myıl olarak bulunmuştur. Küme için ilk kez bulunan metal ve ağır element bolluğu ise sırasıyla [Fe/H]=-0.38 ve Z=0.006 olarak elde edilmiştir.Anahtar kelimeler: Açık yıldız kümeleri-Berkeley 51

  15. Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144 during endothelial differentiation

    Directory of Open Access Journals (Sweden)

    Libermann Towia

    2008-05-01

    Full Text Available Abstract Background Endothelial differentiation occurs during normal vascular development in the developing embryo. This process is recapitulated in the adult when endothelial progenitor cells are generated in the bone marrow and can contribute to vascular repair or angiogenesis at sites of vascular injury or ischemia. The molecular mechanisms of endothelial differentiation remain incompletely understood. Novel approaches are needed to identify the factors that regulate endothelial differentiation. Methods Mouse embryonic stem (ES cells were used to further define the molecular mechanisms of endothelial differentiation. By flow cytometry a population of VEGF-R2 positive cells was identified as early as 2.5 days after differentiation of ES cells, and a subset of VEGF-R2+ cells, that were CD41 positive at 3.5 days. A separate population of VEGF-R2+ stem cells expressing the endothelial-specific marker CD144 (VE-cadherin was also identified at this same time point. Channels lined by VE-cadherin positive cells developed within the embryoid bodies (EBs formed by differentiating ES cells. VE-cadherin and CD41 expressing cells differentiate in close proximity to each other within the EBs, supporting the concept of a common origin for cells of hematopoietic and endothelial lineages. Results Microarray analysis of >45,000 transcripts was performed on RNA obtained from cells expressing VEGF-R2+, CD41+, and CD144+ and VEGF-R2-, CD41-, and CD144-. All microarray experiments were performed in duplicate using RNA obtained from independent experiments, for each subset of cells. Expression profiling confirmed the role of several genes involved in hematopoiesis, and identified several putative genes involved in endothelial differentiation. Conclusion The isolation of CD144+ cells during ES cell differentiation from embryoid bodies provides an excellent model system and method for identifying genes that are expressed during endothelial differentiation and that

  16. Urfa Peynirlerinin Mikrobiyolojik, Kimyasal ve Duyusal Niteliklerinin Saptanması

    Directory of Open Access Journals (Sweden)

    Atilla Yetişmeyen

    2015-02-01

    Full Text Available Bu araştırmada Ankara İli merkezinde satışa sunulan Urfa peynirlerinin mikrobiyolojik, kimyasal ve duyusal özellikleri belirlenmiştir. Mikrobiyolojik incelemeler sonucunda, örneklerde ortalama olarak; 1,0x109 kob/g TAMB (toplam aerobik mezofil bakteri, 1,0x107 kob/g maya ve küf, 3,5x106 EMS/g koliform bakteri, 1,1 x106 EMS/g E. coli ve 1,3x103 kob/g S. aureus olduğu tespit edilmiştir. Elde edilen bulgular, Urfa peynirlerinin üretiminde ve pazarlanması sırasında hijyenik kurallara uyulmadığını ve kötü bir mikrobiyolojik kaliteye sahip olduğunu göstermektedir. Kimyasal analizler sonucu örneklerin kurumadde, yağ, kurumaddede yağ, protein, tuz, kurumaddede tuz, kül, titrasyon asilliği (yüzde laktik asit cinsinden, pH, toplam azot, suda eriyen azot, olgunlaşma katsayısı ve protein olmayan azot değerleri sırasıyla % 48,33, % 22,96, % 47,48, % 17,53, % 6,80, % 17,53, % 2,107, % 1,23, 5,44 pH, % 2,747, % 0,411, % 15,25 ve % 0,26 olarak belirlenmiştir. Duyusal nitelikler bakımından ise; peynirlerin 100 puan üzerinden ortalama 53,71 puan aldıkları tespit edilmiştir. Elde edilen sonuçlardan Urfa peynirlerinin standart bir kalitede olmadığı, üretiminde ve pazarlanmasında hijyenik kurallara uyulmadığı anlaşılmaktadır.

  17. Ortopedik Engelli ve Engelli Olmayan Erkek Ergenlerde Benlik Saygısı ve Beden İmajı

    Directory of Open Access Journals (Sweden)

    Sema Kaner

    2000-02-01

    Full Text Available Bu araştırma, ortopedik engelli ve engelli olmayan ergenlerin benlik saygılarını ve beden imajı algılarını karşılaştırmalı olarak incelemeyi amaçlamaktadır. Veriler 55 ortopedik engelli erkek ve 123 normal erkek ergenden Kendine Saygı Ölçeği ve Beden İmajı Anketi ile toplanmıştır. Sonuçlar, grupların benlik saygıları açısından farklı olmadığım, ancak ortopedik engelli erkeklerin beden imajı algılarının engelli olmayan erkeklerinkinden daha olumlu olduğunu göstermektedir. Engelli olmayan erkeklerde benlik saygısı ve beden imajı arasında anlamlı ve olumlu yönde bir ilişki olmasına rağmen, ortopedik engelli erkeklerde bu iki değişken arasında bir ilişki bulunamamıştır. Engelli olmayan erkeklerde benlik saygısını en iyi yordayıcı değişkenler cinsel organlar, boy, ayaklar ve spor yeteneği, ortopedik engellilerde ise bacaklar, ten, omuzlar, beden kılı ve saçlardır. This study was designed to determine whether self-esteem and body image perception differed among orthopedically handicapped and normal adolescents. Data were collected from 55 orthopedically handicapped males and 123 normal males using Self-Esteem Scale and Body image Questionnaire. The results show that there were no significant differences on the self-esteem scores between groups but body image scores ofthe handicapped males in two groups were higher than the normal femalesAlthough it was found that a positive and significant correlation exist between self-esteem and body image perceptions of nonhandicapped males, no such correlation was foundfor handicapped males. The most predictive body aspects of self-esteem were genital organs, height, legs and sports ability in nonhandicapped males, and legs, skin, shoulders, amount of hair on theface and scalp in orthopedically handicapped males.

  18. Bir Buzağıda Notomeli (Notomelia) ve Pakomeli (Phocomelia) Olgusu

    OpenAIRE

    HAYAT, Ali

    2013-01-01

    Bu vaka takdiminde, 15 günlük dişi melez bir buzağıda notomeli ve pakomeli anomalisi klinik ve radyolojik olarak değerlendirildi. Notomelie ve pakomeli olgusunun buzağılarda çok nadir görülmesi ve ilginç olmasından dolayı bu vaka rapor edilmiştir.

  19. Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development

    Directory of Open Access Journals (Sweden)

    Nick Barker

    2012-09-01

    Full Text Available Multipotent stem cells and their lineage-restricted progeny drive nephron formation within the developing kidney. Here, we document expression of the adult stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor identity of Lgr5+ve cells via in vivo lineage tracing. The appearance and localization of Lgr5+ve cells coincided with that of the S-shaped body around embryonic day 14. Lgr5 expression remained restricted to cell clusters within developing nephrons in the cortex until postnatal day 7, when expression was permanently silenced. In vivo lineage tracing identified Lgr5 as a marker of a stem/progenitor population within nascent nephrons dedicated to generating the thick ascending limb of Henle’s loop and distal convoluted tubule. The Lgr5 surface marker and experimental models described here will be invaluable for deciphering the contribution of early nephron stem cells to developmental defects and for isolating human nephron progenitors as a prerequisite to evaluating their therapeutic potential.

  20. I've been shocked by the recent Panama [...

    NARCIS (Netherlands)

    Benneworth, Paul Stephen

    2016-01-01

    I'VE been shocked by the recent Panama Papers revelations. We all knew that the rich stashed their wealth overseas away from the taxman, but the way it reaches to the top of British government is mind-boggling. The Panama Papers point up the media's importance as the Fourth Estate - a watchdog

  1. Paraziti ve vyjadřování

    Czech Academy of Sciences Publication Activity Database

    Michalec, Vít

    2017-01-01

    Roč. 96, č. 6 (2017), s. 368-368 ISSN 0042-4544 Institutional support: RVO:68378092 Keywords : word jakoby Subject RIV: AI - Linguistics OBOR OECD: Linguistics https://vesmir.cz/cz/casopis/archiv-casopisu/2017/cislo-6/paraziti-ve-vyjadrovani.html

  2. Geneviève Leguerrier | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Geneviève held various managerial positions within IDRC's Finance and Administration division as well as its Grants Administration division. Prior to joining IDRC in 1998, she worked at the Office of the Auditor General. She has a Bachelor's degree in accounting science from the Université du Québec en Outaouais.

  3. Uygulamalı Bilimler ve Mühendislik

    Directory of Open Access Journals (Sweden)

    Recep BAKIŞ

    2012-06-01

    Full Text Available Türkiye’de enerji ihtiyacı, ülkenin öz kaynaklarından karşılanamadığı için yurt dışından ithal edilmektedir. Oysa Türkiye’nin zengin yenilenebilir su kaynakları vardır. Bu makalede, Nehil Çayının (Zap suyu alt havzası sahip olduğu hidroelektrik enerji potansiyeli, bu kaynağın efektif kullanımına ve böylece ülkenin enerji açığını kısmen kapatmaya yönelik olarak araştırılmıştır. Araştırma, Coğrafi Bilgi Sistemleri (GIS ve Uzaktan Algılama metotları kullanılarak yapılmıştır. Ön araştırmaya göre, Nehil Çayı havzasında bir adet barajın planlaması yapılmış ve bu barajın olası maliyetleri ve buradan temin edilebilecek yıllık elektrik enerjisi miktarı hesaplanmıştır. Barajın toplam maliyetleri ve kurulu gücü Simahpp yazılımı ile hesaplanmıştır. Simahpp yazılımına göre, Nehil Çayı havzasında planlanan barajın toplam maliyeti ve kurulu gücü, 41,3x106 US$ ve 25,2 MW olarak elde edilmiştir. Yılda üretebileceği elektrik enerjisi miktarı ise 39,8 GWh olarak belirlenmiştir

  4. A test of the citrate method of PMI estimation from skeletal remains.

    Science.gov (United States)

    Wilson, Sarah J; Christensen, Angi M

    2017-01-01

    Citrate content in bone has been shown to be associated with the postmortem interval (PMI), with citrate decreasing after death as a function of time. Here we test this method using porcine ribs for the period of 1-165days after death, and also assess citrate content and variation from samples placed into two different postmortem environments (terrestrial and aquatic). Higher citrate variation, lower citrate recovery, and a weaker association with time were found in this study as compared to others. Citrate content, however, was found to decrease with increasing PMI, and the method was found to be easy and inexpensive to apply. No significant differences were found in citrate loss between terrestrial and aquatic environments. Although more research is needed, citrate content appears to be a promising new approach in estimating PMI from skeletal remains. Published by Elsevier B.V.

  5. Lactobacillus ve Bifidobacterium Cinsi Bakterilerin Beta Galaktosidaz Enzim Aktivitelerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    Yasemin Kılıç

    2015-02-01

    Full Text Available Bu çalışmada, insan, gıda ve hayvan kaynaklı 39 Lactobacilllus cinsine ait ve yeni doğan gaitasından izole edilmiş 3 Bifidobacterium cinsine ait toplam 42 bakteri kullanılmıştır. O-nitrofenil-beta-D-galaktosit (o-NPG substrat olarak kullanılarak, kültürlerin β-galaktosidaz enzim ve spesifik aktiviteleri belirlenmiştir. Lactobacillus cinsine ait kültürlerden L. fermentum ZYN17 (2.468 U/mg, L. casei LB65 (1.116 U/mg, L. rhamnosus GD11 (1.034 U/mg ve L. acidophilus BAZ36 (0.947 U/mg suşlarının, Bifidobacterium cinsine ait kültürlerden de B. breve A26 (0.726 U/mg suşunun en yüksek spesifik aktivite yeteneğine sahip oldukları tespit edilmiştir. Ayrıca, bakterilerin 5-brom-4-klor-3-indolil-β-D-galaktopiranosit (X-gal substrat bileşiğiyle de nitel olarak enzim aktivitesinin varlığı değerlendirilmiştir. Yüksek spesifik β-galaktozidaz aktivitesi gösteren ZYN17 suşuna ait β-galaktozidaz enziminin optimizasyonu yapılmıştır. β-galaktozidaz enziminin optimum pH’sı 6.8, optimum sıcaklığı 37 ºC ve optimum tamponun potasyum fosfat tamponu olduğu belirlenmiştir.

  6. Membran Distilasyon ve Ozmotik Distilasyon ile Meyve Suyu Konsantrasyonu

    Directory of Open Access Journals (Sweden)

    Pelin Onsekizoğlu

    2015-02-01

    Full Text Available Geleneksel termal evaporasyonla meyve suyu konsantresi üretiminde uygulanan yüksek sıcaklıklar, uçucu aroma maddeleri, vitaminler ve diğer besin öğelerinde kayıplar, pişmiş tat oluşumu, renk bozulması ve insan sağlığı üzerinde olumsuz etkilere neden olmaktadır. Geleneksel uygulamaların yerini almak üzere, hem iyi kalitede hem de güvenilir ürün üretimine olanak tanıyan alternatif konsantrasyon teknolojileri gün geçtikçe önem kazanmaktadır. Bu teknolojiler arasında, membran distilasyon ve ozmotik distilasyon gibi membran uygulamaları meyve sularının oda sıcaklığında veya buna yakın sıcaklıklarda 60-65 ˚Briks ve hatta daha yüksek seviyelere konsantrasyonuna olanak sağlamaları bakımından ön plana çıkmışlardır. Çalışmada, taze ürün karakteristiklerine yakın ürün üretiminde gelecek vadeden bu membran uygulamalarının temel ilkeleri ve meyve suyu sanayinde kullanım potansiyelleri hakkında bilgi verilmiştir.

  7. Approaches and Views of Teachers and Administrators Related to the Usage of Interactive WhiteBoards and Tablet PCs [Öğretmen ve Yöneticilerin Etkileşimli Tahta ve Tablet Bilgisayar Kullanımına Yönelik Yaklaşımları ve Görüşleri

    Directory of Open Access Journals (Sweden)

    Gökhan Dağhan

    2015-12-01

    Full Text Available The aim of the study is to determine approaches of administrators and teachers related to the use of interactive whiteboards and tablet PCs which are distributed in schools within FATİH project. Research was carried out with 32 administrator and 36 teachers who works at FATİH project implementation schools. Seperate forms consisting of different open-ended questions were posed to teachers and administrators. Data was analyzed with content analysis. Administrators indicate that the courses supported by this technology will provide effective learning; courses will be more efficient in a shorter time; motivation, interest and involvement will be affected in a positive direction. Teachers states that technology supported courses will increase the interest of students and develop various skills. According to the statements the most important problem related to the use of these technologies seems to be caused by lack of sufficient educational e-content. Organizing “practical” trainings which aims at gaining ability to create educational e-content for teachers could be solution to sufficient e-content problem. [Bu çalışmanın amacı FATİH projesiyle birlikte okullarda dağıtılan etkileşimli tahta ve tablet bilgisayarlarla ilgili olarak, yöneticilerin ve farklı alanlarda görev yapan öğretmenlerin görüşlerinin ve bu teknolojilerin kullanımlarına yönelik yaklaşımlarının belirlenmesidir. Araştırma FATİH projesinin uygulandığı okullarda görev yapan 32 yönetici ve 36 öğretmenle yürütülmüştür. Öğretmen ve yönetici formu olmak üzere farklı açık uçlu sorulardan oluşan anket katılımcılara yöneltilmiş, veriler içerik analizi ile çözümlenmiştir. Yöneticiler derslerin bu teknolojilerle desteklenerek işlenmesi ile etkili öğrenmelerin sağlanacağını; daha kısa zamanda daha verimli dersler işleneceğini; motivasyon ilgi ve katılımın olumlu yönde etkileneceğini belirtmektedirler.

  8. Geleneksel ve Elektronik Eser Sahiplerinin Telif Hakları, Dijital Haklar Yönetimi: Uluslararası Düzenlemeler ve Fikir ve Sanat Eserleri Kanunu Çerçevesinde Bir Değerlendirme = Copyright of Traditional and Electronic Works’ Owners, Digital Rights Management: An Evaluation within the Framework of International Regulations and Law on Intellectual and Artistic Works

    Directory of Open Access Journals (Sweden)

    Metin Turan

    2016-06-01

    Full Text Available Bilgi ve iletişim teknolojilerinin gelişmesi ile fikri haklar alanında da değişiklikler kaçınılmaz olmuştur. Teknolojik imkânların gelişimi ve dijitalleşme ile dijital eserlerin üretimiyle birlikte telif haklarında sorunlar ortaya çıkmaktadır. Çalışmada, genel olarak, telif haklarının dijital eserlere ve dijital haklar yönetimine yönelik incelenmesi amaçlanmaktadır. Çalışmanın kapsamını dijital haklar yönetimi çerçevesinde 5846 sayılı Fikir ve Sanat Eserleri Kanunu oluşturmaktadır. Bu kapsamda ilgili Yargıtay kararlarının konuları bazında analizi de hedeflenmektedir. Ayrıca, küresel alanda dijital haklar yönetimi alanında önemli hukuksal düzenlemeler olan WIPO (World Intellectual Property Organization Telif Hakları Sözleşmesi ve WIPO İcralar ve Fonogramlar Sözleşmesi çerçevesinde de değerlendirmeler içerik analizi yöntemi ile yapılmaktadır. Çalışma sonunda, bir yandan, Fikir ve Sanat Eserleri Kanunu’nda dijital haklar yönetimine ilişkin hükümler bulunduğu sonucuna varılmaktadır. Diğer yandan, bu kanunda dijital eserlerin telif hakları ve dijital haklar yönetimine dair eksiklikler bulunmakta ve bu eksiklikler mali haklar alanında yoğunlaşmaktadır. / With the development of information and communication technologies, changes are inevitable in the field of intellectual property rights. With the progress of the technological opportunities and digitization, issues in copyright emerge along with production of digital works. In the study, generally, it is aimed at examination of digital works and digital rights management within the context of copyright. The Law No. 5846, Law On Intellectual And Artistic Works within the framework of digital rights management constitutes the scope of the study. In this context, it is aimed also at the analysis of the relevant Supreme Court decisions on the basis of their subjects. In addition, it is evaluated within the scope of WIPO

  9. Advertising Content

    OpenAIRE

    Simon P. Anderson; Régis Renault

    2002-01-01

    Empirical evidence suggests that most advertisements contain little direct informa- tion. Many do not mention prices. We analyze a firm'ss choice of advertising content and the information disclosed to consumers. A firm advertises only product informa- tion, price information, or both; and prefers to convey only limited product information if possible. Extending the "persuasion" game, we show that quality information takes precedence over price information and horizontal product information.T...

  10. Domains and naïve theories.

    Science.gov (United States)

    Gelman, Susan A; Noles, Nicholaus S

    2011-09-01

    Human cognition entails domain-specific cognitive processes that influence memory, attention, categorization, problem-solving, reasoning, and knowledge organization. This article examines domain-specific causal theories, which are of particular interest for permitting an examination of how knowledge structures change over time. We first describe the properties of commonsense theories, and how commonsense theories differ from scientific theories, illustrating with children's classification of biological and nonbiological kinds. We next consider the implications of domain-specificity for broader issues regarding cognitive development and conceptual change. We then examine the extent to which domain-specific theories interact, and how people reconcile competing causal frameworks. Future directions for research include examining how different content domains interact, the nature of theory change, the role of context (including culture, language, and social interaction) in inducing different frameworks, and the neural bases for domain-specific reasoning. WIREs Cogni Sci 2011 2 490-502 DOI: 10.1002/wcs.124 This article is categorized under: Psychology > Reasoning and Decision Making. Copyright © 2010 John Wiley & Sons, Ltd.

  11. CERN hosts Tour du canton de Genève stage

    CERN Multimedia

    Patrice Loïez

    2004-01-01

    CERN hosted the first stage of the 10th Tour du canton de Genève on the evening of Wednesday 26 May. The Tour du canton is an annual race run in four stages over four weeks, and this year started at CERN as part of the Golden Jubilee celebrations. The event attracted over 2000 runners, including over 40 from CERN, as well as a large crowd of onlookers. The 10.5 km route started and finished outside CERN's Main Building, taking in the Swiss countryside, crossing into France and coming back through the tunnel linking the two CERN sites. CERN runners finished in second place in the Enterprise category just 13 seconds behind Rolex S.A., setting up an exciting contest for the remaining stages at Bernex, Meyrin and Jussy.

  12. A Bayesian Framework for Remaining Useful Life Estimation

    Data.gov (United States)

    National Aeronautics and Space Administration — The estimation of remaining useful life (RUL) of a faulty component is at the center of system prognostics and health management. It gives operators a potent tool in...

  13. Robotics to Enable Older Adults to Remain Living at Home

    OpenAIRE

    Pearce, Alan J.; Adair, Brooke; Miller, Kimberly; Ozanne, Elizabeth; Said, Catherine; Santamaria, Nick; Morris, Meg E.

    2012-01-01

    Given the rapidly ageing population, interest is growing in robots to enable older people to remain living at home. We conducted a systematic review and critical evaluation of the scientific literature, from 1990 to the present, on the use of robots in aged care. The key research questions were as follows: (1) what is the range of robotic devices available to enable older people to remain mobile, independent, and safe? and, (2) what is the evidence demonstrating that robotic devices are effec...

  14. Content validity and its estimation

    Directory of Open Access Journals (Sweden)

    Yaghmale F

    2003-04-01

    Full Text Available Background: Measuring content validity of instruments are important. This type of validity can help to ensure construct validity and give confidence to the readers and researchers about instruments. content validity refers to the degree that the instrument covers the content that it is supposed to measure. For content validity two judgments are necessary: the measurable extent of each item for defining the traits and the set of items that represents all aspects of the traits. Purpose: To develop a content valid scale for assessing experience with computer usage. Methods: First a review of 2 volumes of International Journal of Nursing Studies, was conducted with onlyI article out of 13 which documented content validity did so by a 4-point content validity index (CV! and the judgment of 3 experts. Then a scale with 38 items was developed. The experts were asked to rate each item based on relevance, clarity, simplicity and ambiguity on the four-point scale. Content Validity Index (CVI for each item was determined. Result: Of 38 items, those with CVIover 0.75 remained and the rest were discarded reSulting to 25-item scale. Conclusion: Although documenting content validity of an instrument may seem expensive in terms of time and human resources, its importance warrants greater attention when a valid assessment instrument is to be developed. Keywords: Content Validity, Measuring Content Validity

  15. Rodinný dům ve svahu

    OpenAIRE

    Hrubý, Libor

    2013-01-01

    Bakalářská práce, zabývající se projektovou dokumentací stavební části ve stupni pro provedení stavby na novostavbu samostatně stojícího rodinného domu ve svahu. Objekt je dvoupodlažní, podsklepený. Svislé konstrukce z vápenopískového zdícího systému KM Beta Sendwix. Stropní konstrukce z předpjatých stropních panelů Spiroll. Zastřešení provedeno pultovou vegetační střechou se sklonem 10%, plochou střechou s terasovou úpravou a plochou vegetační střechou. Dispozičně je objekt rozdělen na klido...

  16. ADRENOMEDULLİN VE DİYABET Adrenomedullin And Diabetes

    OpenAIRE

    BAYRAM, Zeliha; S. ÖZDEM, Sadi

    2018-01-01

    ÖZETAdrenomedullin (ADM) son dönemde keşfedilen, çok fonksiyonu olan bir peptiddir. Karakteristiketkileri arasında vazodilatör etkisi ve hipotansif özellikleri yer almaktadır. Farklı organlardayaygın bir üretim ve ekspresyonunun olduğu düşünüldüğünde ADM, çeşitli biyolojik sistemlerdeotokrin, endokrin ya da parakrin bir mediyatör olarak rol oynayabilir. Plazma ADM düzeylerininçeşitli hastalıklarda artması, ADM’nin hastalık durumlarında olası bir modülatör rolüne işaretetmektedir. Kardiyovaskü...

  17. Forensic considerations when dealing with incinerated human dental remains.

    Science.gov (United States)

    Reesu, Gowri Vijay; Augustine, Jeyaseelan; Urs, Aadithya B

    2015-01-01

    Establishing the human dental identification process relies upon sufficient post-mortem data being recovered to allow for a meaningful comparison with ante-mortem records of the deceased person. Teeth are the most indestructible components of the human body and are structurally unique in their composition. They possess the highest resistance to most environmental effects like fire, desiccation, decomposition and prolonged immersion. In most natural as well as man-made disasters, teeth may provide the only means of positive identification of an otherwise unrecognizable body. It is imperative that dental evidence should not be destroyed through erroneous handling until appropriate radiographs, photographs, or impressions can be fabricated. Proper methods of physical stabilization of incinerated human dental remains should be followed. The maintenance of integrity of extremely fragile structures is crucial to the successful confirmation of identity. In such situations, the forensic dentist must stabilise these teeth before the fragile remains are transported to the mortuary to ensure preservation of possibly vital identification evidence. Thus, while dealing with any incinerated dental remains, a systematic approach must be followed through each stage of evaluation of incinerated dental remains to prevent the loss of potential dental evidence. This paper presents a composite review of various studies on incinerated human dental remains and discusses their impact on the process of human identification and suggests a step by step approach. Copyright © 2014 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  18. Kazak Mitleri ve Mitik Efsaneleri Hakkında

    OpenAIRE

    İBRAYEV, Şakir; ARIKAN, Metin

    2006-01-01

    Kazak halkının geleneksel dünya görüşü ile söz sanatının kaynağı diyebileceğimiz mitler; dünyanın yaratılışı, nelerin, nasıl, nereden meydana çıktığı, sebebi ve safhaları, etrafımızı kuşatan çevrenin sırları ve özellikleri hakkında söylenen, insanoğlunun ilkel düşüncesinin sonucu meydana gelen olağanüstü anlatmalar, belki de inanışlar, anlayışlar. En eski mitlerin arasında gökyüzü cisimleri - güneş, ay, yıldız ve gezegenler hakkında söylenilen mitleri gösterebiliriz. Bu türdeki mitlerin başlı...

  19. Development of a remaining lifetime management system for NPPS

    International Nuclear Information System (INIS)

    Galvan, J.C.; Regano, M.; Hevia Ruperez, F.

    1994-01-01

    The interest evinced by Spain nuclear power plants in providing a tool to support remaining lifetime management led to UNESA's application to OCIDE in 1992, and the latter's approval, for financing the project to develop a Remaining Lifetime Evaluation System for LWR nuclear power plants. This project is currently being developed under UNESA leadership, and the collaboration of three Spanish engineering companies and a research centre. The paper will describe its objectives, activities, current status and prospects. The project is defined in two phases, the first consisting of the identification and analysis of the main ageing phenomena and their significant parameters and specification of the Remaining Lifetime Evaluation System (RLES), and the second implementation of a pilot application of the RLES to verify its effectiveness. (Author)

  20. Remaining life assessment of a high pressure turbine rotor

    International Nuclear Information System (INIS)

    Nguyen, Ninh; Little, Alfie

    2012-01-01

    This paper describes finite element and fracture mechanics based modelling work that provides a useful tool for evaluation of the remaining life of a high pressure (HP) steam turbine rotor that had experienced thermal fatigue cracking. An axis-symmetrical model of a HP rotor was constructed. Steam temperature, pressure and rotor speed data from start ups and shut downs were used for the thermal and stress analysis. Operating history and inspection records were used to benchmark the damage experienced by the rotor. Fracture mechanics crack growth analysis was carried out to evaluate the remaining life of the rotor under themal cyclic loading conditions. The work confirmed that the fracture mechanics approach in conjunction with finite element modelling provides a useful tool for assessing the remaining life of high temperature components in power plants.

  1. Lymphocyte subset contents in cerebrospinal fluid of children with viral encephalitis

    Directory of Open Access Journals (Sweden)

    An-Ran Xu

    2016-06-01

    Full Text Available Objective: To study the lymphocyte subset contents in cerebrospinal fluid of children with viral encephalitis and their correlation with disease. Methods: Children with viral encephalitis were selected as VE group, children excluded of central nervous system infection by lumbar puncture or children without central nervous system diseases but receiving surgery with spinal anesthesia were selected as control group, and then cerebrospinal fluid and serum were collected to detect lymphocyte subset contents, nerve injury molecule contents as well as inflammatory response indicators and oxidative stress response indicators. Results: CD3+, CD3+CD4+, CD4/CD8 and CD16+CD56+ in cerebrospinal fluid of VE group were lower than those of control group, and both CD3+CD8+ and CD19+ were higher than those of control group; CD3+, CD3+CD4+, CD4/CD8 and CD16+CD56+ in cerebrospinal fluid of children with abnormal MRI were lower than those of children with normal MRI, and both CD3+CD8+ and CD19+ were higher than those of children with normal MRI; NSE, MBP, S-100 and NPT contents in cerebrospinal fluid and serum of VE group were significantly higher than those of control group and had good correlation with lymphocyte subset contents; MMP9, TNF-α and IL-6 contents in cerebrospinal fluid of VE group were significantly higher than those of control group, and SOD and GSH-Px contents were significantly lower than those of control group and had good correlation with lymphocyte subset contents. Conclusions: CD4+/CD8+T lymphocyte ratio and NK cell content decrease, and B lymphocyte content increases in cerebrospinal fluid of children with viral encephalitis, and lymphocyte subset contents have inhibitory effect on MRI manifestation, degree of inflammatory response and oxidative stress response.

  2. On random age and remaining lifetime for populations of items

    DEFF Research Database (Denmark)

    Finkelstein, M.; Vaupel, J.

    2015-01-01

    We consider items that are incepted into operation having already a random (initial) age and define the corresponding remaining lifetime. We show that these lifetimes are identically distributed when the age distribution is equal to the equilibrium distribution of the renewal theory. Then we...... develop the population studies approach to the problem and generalize the setting in terms of stationary and stable populations of items. We obtain new stochastic comparisons for the corresponding population ages and remaining lifetimes that can be useful in applications. Copyright (c) 2014 John Wiley...

  3. Evaluation of remaining behavior of halogen on the fabrication of MOX pellet containing Am

    International Nuclear Information System (INIS)

    Ozaki, Yoko; Osaka, Masahiko; Obayashi, Hiroshi; Tanaka, Kenya

    2004-11-01

    It is important to limit the content of halogen elements, namely fluorine and chlorine that are sources of making cladding material corrode, in nuclear fuel from the viewpoint of quality assurance. The halogen content should be more carefully limited in the MOX fuel containing Americium (Am-MOX), which is fabricated in the Alpha-Gamma Facility (AGF) for irradiation testing to be conducted in the experimental fast reactor JOYO, because fluorine may remain in the sintered pellets owing to a formation of AmF 3 known to have a low vapor pressure and may exceeds the limit of 25 ppm. In this study, a series of experimental determination of halogen element in Am-MOX were performed by a combination method of pyrolysis and ion-chromatography for the purpose of an evaluation of behavior of remaining halogen through the sintering process. Oxygen potential, temperature and time were changed as experimental parameters and their effects on the remaining behavior of halogen were examined. It was confirmed that good pellets, which contained small amount of halogen, could be obtained by the sintering for 3 hour at 1700degC in the oxygen potential range from -520 to -390 kJ/mol. In order to analysis of fluorine chemical form in green pellet, thermal analysis was performed. AmF 3 and PuF 3 have been confirmed to remain in the green pellet. (author)

  4. İNOVASYON VE İNOVASYON GÖSTERGELERİ: AB ÜLKELERİ VE TÜRKİYE KARŞILAŞTIRMASI

    OpenAIRE

    ŞAHİNLİ, Mehmet Arif; KILINÇ, Efecan

    2013-01-01

    Literatürde inovasyonu ölçen ve ülkelerin inovasyon performanslarını ortaya koyan birçok gösterge bulunmaktadır. Bilgi yoğun sektörlerdeki istihdam, Toplam Faktör Verimliliği (TFV), AR&GE harcamaları, patent başvuru ve tescil sayıları, girişimci, araştırmacı ve teknisyen sayıları, ileri teknoloji ihracatı, royalti ve lisans ücretleri, endüstri katma değeri, inovasyon kapasitesi ile Bilgi ve İletişim Teknolojileri (BİT)’nin ihracatı bu göstergelerden bazılarıdır. İnovasyonun en önemli ...

  5. Methodology for Extraction of Remaining Sodium of Used Sodium Containers

    International Nuclear Information System (INIS)

    Jung, Minhwan; Kim, Jongman; Cho, Youngil; Jeong, Jiyoung

    2014-01-01

    Sodium used as a coolant in the SFR (Sodium-cooled Fast Reactor) reacts easily with most elements due to its high reactivity. If sodium at high temperature leaks outside of a system boundary and makes contact with oxygen, it starts to burn and toxic aerosols are produced. In addition, it generates flammable hydrogen gas through a reaction with water. Hydrogen gas can be explosive within the range of 4.75 vol%. Therefore, the sodium should be handled carefully in accordance with standard procedures even though there is a small amount of target sodium remainings inside the containers and drums used for experiment. After the experiment, all sodium experimental apparatuses should be dismantled carefully through a series of draining, residual sodium extraction, and cleaning if they are no longer reused. In this work, a system for the extraction of the remaining sodium of used sodium drums has been developed and an operation procedure for the system has been established. In this work, a methodology for the extraction of remaining sodium out of the used sodium container has been developed as one of the sodium facility maintenance works. The sodium extraction system for remaining sodium of the used drums was designed and tested successfully. This work will contribute to an establishment of sodium handling technology for PGSFR. (Prototype Gen-IV Sodium-cooled Fast Reactor)

  6. Predicting the Remaining Useful Life of Rolling Element Bearings

    DEFF Research Database (Denmark)

    Hooghoudt, Jan Otto; Jantunen, E; Yi, Yang

    2018-01-01

    Condition monitoring of rolling element bearings is of vital importance in order to keep the industrial wheels running. In wind industry this is especially important due to the challenges in practical maintenance. The paper presents an attempt to improve the capability of prediction of remaining...

  7. The experiences of remaining nurse tutors during the transformation ...

    African Journals Online (AJOL)

    The transformation of public services and education in South Africa is part of the political and socioeconomic transition to democracy. Changes are occurring in every fi eld, including that of the health services. A qualitative study was undertaken to investigate the experiences of the remaining nurse tutors at a school of ...

  8. Remaining childless : Causes and consequences from a life course perspective

    NARCIS (Netherlands)

    Keizer, R.

    2010-01-01

    Little is know about childless individuals in the Netherlands, although currently one out of every five Dutch individuals remains childless. Who are they? How did they end up being childless? How and to what extent are their life outcomes influenced by their childlessness? By focusing on individual

  9. Molecular genetic identification of skeletal remains of apartheid ...

    African Journals Online (AJOL)

    The Truth and Reconciliation Commission made significant progress in examining abuses committed during the apartheid era in South Africa. Despite information revealed by the commission, a large number of individuals remained missing when the commission closed its proceedings. This provided the impetus for the ...

  10. Robotics to Enable Older Adults to Remain Living at Home

    Directory of Open Access Journals (Sweden)

    Alan J. Pearce

    2012-01-01

    Full Text Available Given the rapidly ageing population, interest is growing in robots to enable older people to remain living at home. We conducted a systematic review and critical evaluation of the scientific literature, from 1990 to the present, on the use of robots in aged care. The key research questions were as follows: (1 what is the range of robotic devices available to enable older people to remain mobile, independent, and safe? and, (2 what is the evidence demonstrating that robotic devices are effective in enabling independent living in community dwelling older people? Following database searches for relevant literature an initial yield of 161 articles was obtained. Titles and abstracts of articles were then reviewed by 2 independent people to determine suitability for inclusion. Forty-two articles met the criteria for question 1. Of these, 4 articles met the criteria for question 2. Results showed that robotics is currently available to assist older healthy people and people with disabilities to remain independent and to monitor their safety and social connectedness. Most studies were conducted in laboratories and hospital clinics. Currently limited evidence demonstrates that robots can be used to enable people to remain living at home, although this is an emerging smart technology that is rapidly evolving.

  11. Authentic leadership: becoming and remaining an authentic nurse leader.

    Science.gov (United States)

    Murphy, Lin G

    2012-11-01

    This article explores how chief nurse executives became and remained authentic leaders. Using narrative inquiry, this qualitative study focused on the life stories of participants. Results demonstrate the importance of reframing, reflection in alignment with values, and the courage needed as nurse leaders progress to authenticity.

  12. Robotics to enable older adults to remain living at home.

    Science.gov (United States)

    Pearce, Alan J; Adair, Brooke; Miller, Kimberly; Ozanne, Elizabeth; Said, Catherine; Santamaria, Nick; Morris, Meg E

    2012-01-01

    Given the rapidly ageing population, interest is growing in robots to enable older people to remain living at home. We conducted a systematic review and critical evaluation of the scientific literature, from 1990 to the present, on the use of robots in aged care. The key research questions were as follows: (1) what is the range of robotic devices available to enable older people to remain mobile, independent, and safe? and, (2) what is the evidence demonstrating that robotic devices are effective in enabling independent living in community dwelling older people? Following database searches for relevant literature an initial yield of 161 articles was obtained. Titles and abstracts of articles were then reviewed by 2 independent people to determine suitability for inclusion. Forty-two articles met the criteria for question 1. Of these, 4 articles met the criteria for question 2. Results showed that robotics is currently available to assist older healthy people and people with disabilities to remain independent and to monitor their safety and social connectedness. Most studies were conducted in laboratories and hospital clinics. Currently limited evidence demonstrates that robots can be used to enable people to remain living at home, although this is an emerging smart technology that is rapidly evolving.

  13. Dinosaur remains from the type Maastrichtian: An update

    NARCIS (Netherlands)

    Weishampel, David B.; Mulder, Eric W A; Dortangs, Rudi W.; Jagt, John W M; Jianu, Coralia Maria; Kuypers, Marcel M M; Peeters, Hans H G; Schulp, Anne S.

    1999-01-01

    Isolated cranial and post-cranial remains of hadrosaurid dinosaurs have been collected from various outcrops in the type area of the Maastrichtian stage during the last few years. In the present contribution, dentary and maxillary teeth are recorded from the area for the first time. Post-cranial

  14. MONSOONS MUDE AND GOLD MUSONLAR GEMİ VE ALTIN

    Directory of Open Access Journals (Sweden)

    Paul LUNDE

    2009-12-01

    Full Text Available The “global economy” of the Middle Ages was created by linking the Indian Ocean trading networks with those of the Mediterranean Sea and its African and European hinterlands. These products, together with ceramics, textiles and sugar provided from Egypt and Syria, reached European markets almost exclusively through the Italian maritime republics of Amalfi, Pisa, Genoa and Venice. Especially the direction of the monsoon winds in the Indian Ocean and the course of the Venice trade ships were at the same direction. Thereby, Venice trade ships set out toward the end of August and made their way slowly through the Adriatic and the Aegean to Cyprus and Alexandria, timing their arrival there to coincide with the availability of monsoon-borne and by this way the products which are ned carried through Europe. İt is important to emphasize this subject that North Europe economy depends on this Monsoons where they became at Indian Ocean. As a maritime republic dedicated itself to the international trade, Venice was an anomaly in a feudal Europe that measured wealth by land, not money. Therefor this idea were encouraging their believing about ending the monopoly of the Muslim trade at the Indian Ocean. Ortaçağın global ekonomisini Hint Okyanusu ticaret hattı ile Akdeniz, Afrika ve Avrupa Hinterlantları arasındaki ticaret bağlantısı teşkil ediyordu. Avrupa ekonomisindeki gelişmelere paralel olarak Batı dünyasının gereksinim duyduğu ve Mısır ile Suriye’den tedarik edilen şeker, tekstil, seramik gibi ürünler Amalfi, Pisa, Ceneviz ve Venedik gibi İtalyan Cumhuriyetleri aracılığıyla Avrupa pazarlarına taşınmaktaydı. Özellikle Hint Okyanusu üzerindeki muson rüzgârlarının yönleriyle Venedik ticaret gemilerinin rotaları aynı doğrultudaydı. Bu suretle Ağustos ayının sonuna doğru İtalya’dan ayrılan gemiler, Adriyatik, Ege ve Kıbrıs rotasından İskenderiye’ye ulaştığı esnada musonlarla kar

  15. Digital Natives, Social Networks and the Future of Libraries Dijital Yerliler, Sosyal Ağlar ve Kütüphanelerin Geleceği

    Directory of Open Access Journals (Sweden)

    Yaşar Tonta

    2009-12-01

    Full Text Available Facebook, MySpace, Flickr and YouTube are currently among the most frequently visited websites with Web 2.0 features. They are used not only for social networking and entertainment but also for access to information, for learning and for carrying out professional work. Social networks commonly have Web 2.0 features, offer personalized services and allow users to incorporate their own content easily and describe, organize and share it with others, thereby enriching users’ experience. Some users tend to “live” on those social networks and expect information providing organizations to offer similar services. They want libraries to be as accessible, flexible, open to collaboration and sharing as that of social networks and heighten the expectations from such institutions. The future of libraries is closely associated with how successfully they meet the demands of digital users. Otherwise, the “net generation” or the “digital natives” grown up with the Web, Google and Facebook would see libraries as outdated institutions and “take their business elsewhere” to satisfy their information needs. In this paper, the impact of the technological convergence on information providing organizations is reviewed and the challenges and opportunities facing libraries in the digital environment are discussed. Facebook, MySpace, Flickr ve YouTube gibi Web 2.0 özelliklerine sahip sosyal ağlar en çok ziyaret edilen web siteleri arasında yer almaktadır. Sosyal ağlar sadece sosyalleşmek ve eğlenmek amacıyla değil, bilgiye erişmek, öğrenmek ve profesyonel iş yapmak amacıyla da kullanılmaktadır. Sosyal ağların sağladığı işbirliği, kişiselleştirme, kullanıcı destekli içerik ekleme ve üst veri gibi özellikler kullanıcı deneyimini zenginleştirmekte ve bu web sitelerini daha çekici kılmaktadır. Kütüphanelerin de sosyal ağlar kadar erişilebilir, esnek, işbirliği ve paylaşıma açık olmasını bekleyen kullan

  16. Instrumental neutron activation analysis of prehistoric and ancient bone remains

    International Nuclear Information System (INIS)

    Vasidov, A.; Osinskaya, N.S.; Khatamov, Sh.; Rakhmanova, T.

    2008-01-01

    Instrumental neutron activation analysis (INAA) was used to study the element contents in bones of prehistoric dinosaurs and bones of an ancient bear and an archantrop (ancient person), which were found on the territory of Uzbekistan. Concentrations of more than 25 elements were in the range of 0.043-3600 mg/kg. Multielement analyses of bone and soil samples were carried out by INAA using the WWR-SM research nuclear reactor. Results of measurements have shown that in the dinosaurs bones the concentration of the rare earth elements (REEs) were within 280-3200 mg/kg; the uranium content reached a very high value, up to 180 mg/kg, while in soils coating the dinosaurs bones this content was 4.2 mg/kg; in the bones of the archantrop it was 1.53 mg/kg and in the bones of a standard person its amount is less than 0.016 mg/kg. (author)

  17. İMDAT AVŞAR AND HIS STORYTELLING İMDAT AVŞAR VE HİKÂYECİLİĞİ

    Directory of Open Access Journals (Sweden)

    Zehra YAZBAHAR

    2011-01-01

    Full Text Available With his stories in his first book which is Steppe Which Fade To Crocuses he published in 2010, Imdat Avşar reflects our society and our traditional values. In this study which is primarily composed of two major parts, after giving brief information about Imdat Avşar in the first section, the art of storytelling will be part in the second section and the stories in the mentioned book are gotten the grips with narrator, viewpoint, content, characters, language and style. İmdat Avşar, 2010 yılında yayımladığı Çiğdemleri Solan Bozkır isimli ilk hikâye kitabındaki hikâyeleri ile aynasını Türk toplumuna ve onun geleneksel değerlerine tutar. Esas itibariyle iki ana bölümden oluşan bu çalışmada, ilk bölümde İmdat Avşar hakkında kısa bir bilgi verildikten sonra ikinci bölümde hikâyeciliğine geçilecek ve sözü edilen kitabındaki hikâyeleri, anlatıcı ve bakış açısı, içerik ve kişiler kadrosu, dil ve üslûp başlıkları altında ele alınacaktır.

  18. Safety provision for nuclear power plants during remaining running time

    International Nuclear Information System (INIS)

    Rossnagel, Alexander; Hentschel, Anja

    2012-01-01

    With the phasing-out of the industrial use of nuclear energy for the power generation, the risk of the nuclear power plants has not been eliminated in principle, but only for a limited period of time. Therefore, the remaining nine nuclear power plants must also be used for the remaining ten years according to the state of science and technology. Regulatory authorities must substantiate the safety requirements for each nuclear power plant and enforce these requirements by means of various regulatory measures. The consequences of Fukushima must be included in the assessment of the safety level of nuclear power plants in Germany. In this respect, the regulatory authorities have the important tasks to investigate and assess the security risks as well as to develop instructions and orders.

  19. Structural remains at the early mediaeval fort at Raibania, Orissa

    Directory of Open Access Journals (Sweden)

    Bratati Sen

    2013-11-01

    Full Text Available The fortifications of mediaeval India occupy an eminent position in the history of military architecture. The present paper deals with the preliminary study of the structural remains at the early mediaeval fort at Raibania in the district of Balasore in Orissa. The fort was built of stone very loosely kept together. The three-walled fortification interspersed by two consecutive moats, a feature evidenced at Raibania, which is unparallel in the history of ancient and mediaeval forts and fortifications in India. Several other structures like the Jay-Chandi Temple Complex, a huge well, numerous tanks and remains of an ancient bridge add to the uniqueness of the Fort in the entire eastern region.

  20. Mineral remains of early life on Earth? On Mars?

    Science.gov (United States)

    Iberall, Robbins E.; Iberall, A.S.

    1991-01-01

    The oldest sedimentary rocks on Earth, the 3.8-Ga Isua Iron-Formation in southwestern Greenland, are metamorphosed past the point where organic-walled fossils would remain. Acid residues and thin sections of these rocks reveal ferric microstructures that have filamentous, hollow rod, and spherical shapes not characteristic of crystalline minerals. Instead, they resemble ferric-coated remains of bacteria. Because there are no earlier sedimentary rocks to study on Earth, it may be necessary to expand the search elsewhere in the solar system for clues to any biotic precursors or other types of early life. A study of morphologies of iron oxide minerals collected in the southern highlands during a Mars sample return mission may therefore help to fill in important gaps in the history of Earth's earliest biosphere. -from Authors

  1. ENDODONTİDE FLARE-UP’IN ÖNLENMESİ VE TEDAVİSİ

    OpenAIRE

    GÜLER, Buğra; AYDEMİR, Hikmet

    2015-01-01

    ÖZETAğrı ve ağrı korkusu hasta ve hekim ilişkisinin ciddi problemlerinden birisidir. Endodontik tedavi sırasında veya sonrasında meydana gelen ağrı şikâyetlerinin azaltılması için çeşitli tedavi şekilleri ve önlemler mevcuttur. Bu tedavi şekilleri, dişin oklüzyondan düşürülmesi, premedikasyon, drenajın sağlanması, kanal içi ve sistemik medikament işlemlerini içermektedir. Bu derlemede, flare-up meydana geldiğinde hastanın nasıl yönetilmesi gerektiğinin ve flare-up’ın önlenmesi ve tedavisi içi...

  2. USING CONDITION MONITORING TO PREDICT REMAINING LIFE OF ELECTRIC CABLES

    International Nuclear Information System (INIS)

    LOFARO, R.; SOO, P.; VILLARAN, M.; GROVE, E.

    2001-01-01

    Electric cables are passive components used extensively throughout nuclear power stations to perform numerous safety and non-safety functions. It is known that the polymers commonly used to insulate the conductors on these cables can degrade with time; the rate of degradation being dependent on the severity of the conditions in which the cables operate. Cables do not receive routine maintenance and, since it can be very costly, they are not replaced on a regular basis. Therefore, to ensure their continued functional performance, it would be beneficial if condition monitoring techniques could be used to estimate the remaining useful life of these components. A great deal of research has been performed on various condition monitoring techniques for use on electric cables. In a research program sponsored by the U.S. Nuclear Regulatory Commission, several promising techniques were evaluated and found to provide trendable information on the condition of low-voltage electric cables. These techniques may be useful for predicting remaining life if well defined limiting values for the aging properties being measured can be determined. However, each technique has advantages and limitations that must be addressed in order to use it effectively, and the necessary limiting values are not always easy to obtain. This paper discusses how condition monitoring measurements can be used to predict the remaining useful life of electric cables. The attributes of an appropriate condition monitoring technique are presented, and the process to be used in estimating the remaining useful life of a cable is discussed along with the difficulties that must be addressed

  3. Study on remain actinides recovery in pyro reprocessing

    International Nuclear Information System (INIS)

    Suharto, Bambang

    1996-01-01

    The spent fuel reprocessing by dry process called pyro reprocessing have been studied. Most of U, Pu and MA (minor actinides) from the spent fuel will be recovered and be fed back to the reactor as new fuel. Accumulation of remain actinides will be separated by extraction process with liquid cadmium solvent. The research was conducted by computer simulation to calculate the stage number required. The calculation's results showed on the 20 stages extractor more than 99% actinides can be separated. (author)

  4. US GAAP vs. IFRS – A COMPARISON OF REMAINING DIFFERENCES

    OpenAIRE

    Mihelčić, Eva

    2008-01-01

    In spite of the on-going harmonization process, there are still some differences between US GAAP and IFRS. Currently, companies listed on the New York Stock Exchange, which are reporting according to IFRS, must still prepare the reconciliation to US GAAP, to show the financial statements compliant with US GAAP as well. This article presents an overview of the remaining major differences between US GAAP and IFRS, descriptive as well as table-wise. First, the standards compared are shortly intr...

  5. Structural remains at the early mediaeval fort at Raibania, Orissa

    OpenAIRE

    Sen, Bratati

    2013-01-01

    The fortifications of mediaeval India occupy an eminent position in the history of military architecture. The present paper deals with the preliminary study of the structural remains at the early mediaeval fort at Raibania in the district of Balasore in Orissa. The fort was built of stone very loosely kept together. The three-walled fortification interspersed by two consecutive moats, a feature evidenced at Raibania, w...

  6. Neanderthal infant and adult infracranial remains from Marillac (Charente, France).

    Science.gov (United States)

    Dolores Garralda, María; Maureille, Bruno; Vandermeersch, Bernard

    2014-09-01

    At the site of Marillac, near the Ligonne River in Marillac-le-Franc (Charente, France), a remarkable stratigraphic sequence has yielded a wealth of archaeological information, palaeoenvironmental data, as well as faunal and human remains. Marillac must have been a sinkhole used by Neanderthal groups as a hunting camp during MIS 4 (TL date 57,600 ± 4,600BP), where Quina Mousterian lithics and fragmented bones of reindeer predominate. This article describes three infracranial skeleton fragments. Two of them are from adults and consist of the incomplete shafts of a right radius (Marillac 24) and a left fibula (Marillac 26). The third fragment is the diaphysis of the right femur of an immature individual (Marillac 25), the size and shape of which resembles those from Teshik-Tash and could be assigned to a child of a similar age. The three fossils have been compared with the remains of other Neanderthals or anatomically Modern Humans (AMH). Furthermore, the comparison of the infantile femora, Marillac 25 and Teshik-Tash, with the remains of several European children from the early Middle Ages clearly demonstrates the robustness and rounded shape of both Neanderthal diaphyses. Evidence of peri-mortem manipulations have been identified on all three bones, with spiral fractures, percussion pits and, in the case of the radius and femur, unquestionable cutmarks made with flint implements, probably during defleshing. Traces of periostosis appear on the fibula fragment and on the immature femoral diaphysis, although their aetiology remains unknown. Copyright © 2014 Wiley Periodicals, Inc.

  7. Calibration of C-14 dates: some remaining uncertainties and limitations

    International Nuclear Information System (INIS)

    Burleigh, R.

    1975-01-01

    A brief review is presented of the interpretation of radiocarbon dates in terms of calendar years. An outline is given of the factors that make such correlations necessary and of the work that has so far been done to make them possible. The calibration of the C-14 timescale very largely depends at present on the bristlecone pine chronology, but it is clear that many detailed uncertainties still remain. These are discussed. (U.K.)

  8. Flower choice by naïve young crab spiders and the effect of subsequent experience.

    Science.gov (United States)

    Morse

    2000-05-01

    Initial responses of naïve individuals to critical environmental stimuli provide important information about the innate contribution to behaviour, and subsequent responses to the same stimuli may show the role of experience in mediating those initial responses. To test the role of these factors, I measured initial patch choices and giving-up responses of just-emerged, naïve, second-instar crab spiders, Misumena vatia, on several hunting sites they encountered after leaving their natal nests. In follow-up tests I measured the effects of these experiences on subsequent patch choice decisions. The choice of hunting sites is a vital decision at all stages of the life cycle for sit-and-wait predators such as Misumena. In their initial tests these spiderlings remained more frequently on goldenrod (Solidago spp.) flowers than on green or yellow goldenrod buds, a preference they retained through tests run on 5 consecutive days. Individuals on green and yellow buds shifted sites more quickly and frequently than those from flowers, and made most of these moves to flowers, which attracted many more prey than did buds. These differences were not affected by age, energetic condition, or loss of information over the period of the experiment. Once spiderlings moved from buds, they showed a high, increasing tendency to move from buds in subsequent runs, those from flowers showed a consistently low tendency. These results suggest that spiderlings retain their innate behavioural patterns through the second instar, but that experience also plays a modest role in patch choice at this stage. Copyright 2000 The Association for the Study of Animal Behaviour.

  9. Prognostic modelling options for remaining useful life estimation by industry

    Science.gov (United States)

    Sikorska, J. Z.; Hodkiewicz, M.; Ma, L.

    2011-07-01

    Over recent years a significant amount of research has been undertaken to develop prognostic models that can be used to predict the remaining useful life of engineering assets. Implementations by industry have only had limited success. By design, models are subject to specific assumptions and approximations, some of which are mathematical, while others relate to practical implementation issues such as the amount of data required to validate and verify a proposed model. Therefore, appropriate model selection for successful practical implementation requires not only a mathematical understanding of each model type, but also an appreciation of how a particular business intends to utilise a model and its outputs. This paper discusses business issues that need to be considered when selecting an appropriate modelling approach for trial. It also presents classification tables and process flow diagrams to assist industry and research personnel select appropriate prognostic models for predicting the remaining useful life of engineering assets within their specific business environment. The paper then explores the strengths and weaknesses of the main prognostics model classes to establish what makes them better suited to certain applications than to others and summarises how each have been applied to engineering prognostics. Consequently, this paper should provide a starting point for young researchers first considering options for remaining useful life prediction. The models described in this paper are Knowledge-based (expert and fuzzy), Life expectancy (stochastic and statistical), Artificial Neural Networks, and Physical models.

  10. Remaining useful life estimation based on discriminating shapelet extraction

    International Nuclear Information System (INIS)

    Malinowski, Simon; Chebel-Morello, Brigitte; Zerhouni, Noureddine

    2015-01-01

    In the Prognostics and Health Management domain, estimating the remaining useful life (RUL) of critical machinery is a challenging task. Various research topics including data acquisition, fusion, diagnostics and prognostics are involved in this domain. This paper presents an approach, based on shapelet extraction, to estimate the RUL of equipment. This approach extracts, in an offline step, discriminative rul-shapelets from an history of run-to-failure data. These rul-shapelets are patterns that are selected for their correlation with the remaining useful life of the equipment. In other words, every selected rul-shapelet conveys its own information about the RUL of the equipment. In an online step, these rul-shapelets are compared to testing units and the ones that match these units are used to estimate their RULs. Therefore, RUL estimation is based on patterns that have been selected for their high correlation with the RUL. This approach is different from classical similarity-based approaches that attempt to match complete testing units (or only late instants of testing units) with training ones to estimate the RUL. The performance of our approach is evaluated on a case study on the remaining useful life estimation of turbofan engines and performance is compared with other similarity-based approaches. - Highlights: • A data-driven RUL estimation technique based on pattern extraction is proposed. • Patterns are extracted for their correlation with the RUL. • The proposed method shows good performance compared to other techniques

  11. Direct dating of Early Upper Palaeolithic human remains from Mladec.

    Science.gov (United States)

    Wild, Eva M; Teschler-Nicola, Maria; Kutschera, Walter; Steier, Peter; Trinkaus, Erik; Wanek, Wolfgang

    2005-05-19

    The human fossil assemblage from the Mladec Caves in Moravia (Czech Republic) has been considered to derive from a middle or later phase of the Central European Aurignacian period on the basis of archaeological remains (a few stone artefacts and organic items such as bone points, awls, perforated teeth), despite questions of association between the human fossils and the archaeological materials and concerning the chronological implications of the limited archaeological remains. The morphological variability in the human assemblage, the presence of apparently archaic features in some specimens, and the assumed early date of the remains have made this fossil assemblage pivotal in assessments of modern human emergence within Europe. We present here the first successful direct accelerator mass spectrometry radiocarbon dating of five representative human fossils from the site. We selected sample materials from teeth and from one bone for 14C dating. The four tooth samples yielded uncalibrated ages of approximately 31,000 14C years before present, and the bone sample (an ulna) provided an uncertain more-recent age. These data are sufficient to confirm that the Mladec human assemblage is the oldest cranial, dental and postcranial assemblage of early modern humans in Europe and is therefore central to discussions of modern human emergence in the northwestern Old World and the fate of the Neanderthals.

  12. Remaining life diagnosis method and device for nuclear reactor

    International Nuclear Information System (INIS)

    Yamamoto, Michiyoshi.

    1996-01-01

    A neutron flux measuring means is inserted from the outside of a reactor pressure vessel during reactor operation to forecast neutron-degradation of materials of incore structural components in the vicinity of portions to be measured based on the measured values, and the remaining life of the reactor is diagnosed by the forecast degraded state. In this case, the neutron fluxes to be measured are desirably fast and/or medium neutron fluxes. As the positions where the measuring means is to be inserted, for example, the vicinity of the structural components at the periphery of the fuel assembly is selected. Aging degradation characteristics of the structural components are determined by using the aging degradation data for the structural materials. The remaining life is analyzed based on obtained aging degradation characteristics and stress evaluation data of the incore structural components at portions to be measured. Neutron irradiation amount of structural components at predetermined positions can be recognized accurately, and appropriate countermeasures can be taken depending on the forecast remaining life thereby enabling to improve the reliability of the reactor. (N.H.)

  13. Postmortem Scavenging of Human Remains by Domestic Cats

    Directory of Open Access Journals (Sweden)

    Ananya Suntirukpong, M.D.

    2017-11-01

    Full Text Available Objective: Crime scene investigators, forensic medicine doctors and pathologists, and forensic anthropologists frequently encounter postmortem scavenging of human remains by household pets. Case presentation: The authors present a case report of a partially skeletonized adult male found dead after more than three months in his apartment in Thailand. The body was in an advanced stage of decomposition with nearly complete skeletonization of the head, neck, hands, and feet. The presence of maggots and necrophagous (flesh eating beetles on the body confirmed that insects had consumed much of the soft tissues. Examination of the hand and foot bones revealed canine tooth puncture marks. Evidence of chewing indicated that one or more of the decedent’s three house cats had fed on the body after death. Recognizing and identifying carnivore and rodent activity on the soft flesh and bones of human remains is important in interpreting and reconstructing postmortem damage. Thorough analysis may help explain why skeletal elements are missing, damaged, or out of anatomical position. Conclusion: This report presents a multi-disciplinary approach combining forensic anthropology and forensic medicine in examining and interpreting human remains.

  14. Ankara Merkez İlçeleri ve Köylerinde Ev Konserveciliği Teknikleri ve Konservelerin Bazı Organoleptik ve Mikrobiyolojik Özellikleri

    Directory of Open Access Journals (Sweden)

    Necla Yazıcı

    2015-02-01

    Full Text Available Bu çalışmada, Ankara İlinin merkez ilçelerine bağlı köylerde yapılmakta olan ev konserveciliği uygulamalarına ait tekniklerin saptanması ve yapılan konservelerin organoleptik ve mikrobiyolojik analizlere dayanarak, bazı kalite özelliklerinin belirlenmesi amaçlanmıştır. Araştırmada Ankara İlinin merkez ilçelerine bağlı, 13 köyde, 154 deneğe anket uygulanmış ve ayrıca deneklerden toplanan 50 konserve örneği organoleptik ve mikrobiyolojik testlere tabi tutulmuştur. Araştırma bulgularına göre deneklerin %97.40’ı sebze konservesi kavanozlarını açık kazanda kaynatmaktadırlar. Deneklerin %48.00’i kavanozları boşluk bırakmadan, %30’u ise yarısına kadar doldurmaktadırlar. Kavanozların havasını alan deneklerin oranı %80.50’dir. Kaynatma işleminde süre tutan denekler %85.71 oranındadır. Bu deneklerin de %71.42’si kaynatma işlemi için yeterli süre uygulamaktadırlar. Konservelerde kaynatmadan sonra bozulma gören denekler %70.13, saklama sırasında bozulma görenler %40.91 oranındadır. Kaynatmadan sonra meydana gelen bozulmaların başında %73.14 oranı ile kapak atması gelmektedir. Toplam 50 konserve örneğinin organoleptik analizi sonucunda örneklerin %18’i renk, %30’u koku, %18’i genel görünüş bakımından kötü olarak değerlendirilmiştir. Mikrobiyolojik analizler sonucunda ise toplam 50 konserve örneğinin %20’sinde üreme görülmüştür. Alınan örneklerin, aerob koşullarda %14’ünde 35 oC de; %16’sında 55 oC’de; anaerob koşullarda ise %12’sinde 35 oC’de; %16’sında 55 oC’de üreme görülmüştür.

  15. Simidin Demir ve Çinko Mineralleriyle Zenginleştirilmesi ve in vitro Mineral Biyoyararlılığının Saptanması

    Directory of Open Access Journals (Sweden)

    Melis Sözer Güzelcan

    2015-02-01

    Full Text Available Bu çalışmada, Türkiye’de sıklıkla görülen mineral yetersizliğine bağlı beslenme sorunlarına bir yaklaşım olması açısından geleneksel bir gıda olan simidin demir ve çinko mineralleri ile zenginleştirilmesi, bu mi­nerallerin biyoyararlılığı ve genellikle simit ile birlikte tüketilen çay ve ayran içeceklerinin mineral biyoya­rarlılığı üzerine etkileri ve ayrıca tahıllı gıdalarda bulunan fitik asidin mineral biyoyararlılığına etkisinin saptanması amaçlanmıştır. Bu amaçla, simit, demir ve çinko mineralleri ile zenginleştirilmiş simit, çay + zenginleştirilmiş simit ve ayran + zenginleştirilmiş simit örneklerinde demir ve çinko minerallerinin içe­rikleri ve in vitro mineral biyoyararlılıkları saptanmıştır. Simit, demir ve çinko mineralleri ile zenginleşti­rilmiş simit örneklerinde fitik asit içerikleri de belirlenmiştir. Çalışma sonucunda; simitteki demir ve çinko minerallerinin biyoyararlılıkları sırasıyla % 3.14 ve % 6.78; zenginleştirilmiş simitteki bu minerallerin biyo­yararlılıkları sırasıyla % 1.96 ve % 2.84 olarak saptanmıştır. Demir mineralinin biyoyararlılığı simit ayran ve çayla tüketildiği zaman sırasıyla % 2.14 ile % 2.23; çinko mineralinin biyoyararlılığı sırasıyla % 6.38 ve % 5.09 olarak belirlenmiştir. Çay ve ayran zenginleştirilmiş simit ile birlikte tüketildiği zaman demir mineralinin biyoyararlılığının değişmediği; çinko mineralinin biyoyararlılığının arttığı saptanmıştır. Simit ve zenginleş­tirilmiş simitteki fitik asit içerikleri sırasıyla 0.154 g/100g ve 0.159 g/100g olarak belirlenmiştir. Fitat:demir minerali ve fitat:çinko minerali molar oranları hesaplanarak mineral biyoyararlılığı değerlendirilmiştir.

  16. The Remains of the Day in Dissociative Amnesia

    Directory of Open Access Journals (Sweden)

    Angelica Staniloiu

    2012-04-01

    Full Text Available Memory is not a unity, but is divided along a content axis and a time axis, respectively. Along the content dimension, five long-term memory systems are described, according to their hierarchical ontogenetic and phylogenetic organization. These memory systems are assumed to be accompanied by different levels of consciousness. While encoding is based on a hierarchical arrangement of memory systems from procedural to episodic-autobiographical memory, retrieval allows independence in the sense that no matter how information is encoded, it can be retrieved in any memory system. Thus, we illustrate the relations between various long-term memory systems by reviewing the spectrum of abnormalities in mnemonic processing that may arise in the dissociative amnesia—a condition that is usually characterized by a retrieval blockade of episodic-autobiographical memories and occurs in the context of psychological trauma, without evidence of brain damage on conventional structural imaging. Furthermore, we comment on the functions of implicit memories in guiding and even adaptively molding the behavior of patients with dissociative amnesia and preserving, in the absence of autonoetic consciousness, the so-called “internal coherence of life”.

  17. Thermal effects of condensing water have remained local

    International Nuclear Information System (INIS)

    Ilus, E.

    1997-01-01

    General eutrophication of the Gulf of Finland has played a major role in the biological changes that have taken place in the sea area off Loviisa nuclear power plant. The quantities of plant nutrients in the water are now 1.5 to 2 times greater than 20 years ago. Changes attributable to the thermal effects of the power plant's cooling waters have been relatively small, and they have been restricted to the immediate surroundings of the discharge area. The most distinct environmental effects have been discovered in the temperatures of sea water, in ice conditions and in water currents within the discharge area of cooling water. The most visible biological change that has a direct link to the thermal load resulting from the power plant is the more abundant aquatic flora near the discharge point of cooling water on the southwestern shores of the Haestholmsfjaerden. Similar growth of aquatic flora has also been discovered near the discharge outlet of Olkiluoto plant, although the nutrient contents of water there are only half of the values measured in the Loviisa area. Regular radiation monitoring of the areas surrounding the nuclear power plants began before the start up of the plants. The contents of radioactive substances discovered have been small and in agreement with the release data given by the power companies. (orig.)

  18. FvVE1 Regulates Biosynthesis of Fumonisins and Fusarins in Fusarium verticillioides

    Science.gov (United States)

    MYUNG, KYUNG; LI, SHAOJIE; BUTCHKO, ROBERT A.E.; BUSMAN, MARK; PROCTOR, ROBERT H; ABBAS, HAMED K.; CALVO, ANA M.

    2009-01-01

    The veA gene positively regulates sterigmatocystin production in Aspergillus nidulans and aflatoxin production in A. parasiticus and A. flavus. Whether veA homologs have a role in regulating secondary metabolism in other fungal genera is unknown. In this study, we examined the role of the veA homolog, FvVE1, on production of two mycotoxin families, fumonisins and fusarins, in the important corn pathogen F. verticillioides. We found that FvVE1 deletion completely suppressed fumonisin production on two natural substrates, corn and rice. Furthermore, our results revealed that FvVE1 is necessary for the expression of the pathway-specific regulatory gene FUM21 and structural genes in the fumonisin biosynthetic gene (FUM) cluster. FvVE1 deletion also blocked production of fusarins. The effects of FvVE1 deletion on the production of these toxins were found to be the same in two separate mating types. Our results strongly suggest that FvVE1 play an important role in regulating mycotoxin production in F. verticillioides. PMID:19382792

  19. Uygulamalı Bilimler ve Mühendislik

    Directory of Open Access Journals (Sweden)

    Edip ŞENYÜREK

    2012-12-01

    Full Text Available İnternet üzerinden sanal firmalar aracılığıyla alışveriş yapmak artan ilgi görmektedir. Müşteriler beğenebilecekleri ürünleri zaman ve/veya paralarını boşa harcamadan satın almak isterler. Müşterilerine bu süreçte yardımcı olmak için birçok sanal şirket öneri sistemlerinden yararlanıp müşterilerine en-iyi-N önerileri sunmaktadır. En benzer varlıkları belirlemede kullanılan benzerlik ölçütleri en-iyi-N önerileri hizmetinin genel performansını etkileyebilir. İkili değerler üzerinde işlem yapan birçok benzerlik ölçütü bulunmasına rağmen bunların en-iyi-N önerilerinin doğruluğu ve çevrimiçi performansı üzerindeki etkisi detaylı biçimde çalışılmamıştır. yapıldı. Ayrıca en-iyi-N öneri algoritması en benzer kullanıcıların verisi öneri üretilirken kullanılacak şekilde değiştirildi. Değişen kontrol parametrelerinin performansa olan etkisi araştırıldı. Deneysel sonuçlar doğruluk ve performans açısından analiz edilerek bazı öneriler sunuldu

  20. VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression

    Science.gov (United States)

    Morini, Marco F.; Giampietro, Costanza; Corada, Monica; Pisati, Federica; Lavarone, Elisa; Cunha, Sara I.; Conze, Lei L.; O’Reilly, Nicola; Joshi, Dhira; Kjaer, Svend; George, Roger; Nye, Emma; Ma, Anqi; Jin, Jian; Mitter, Richard; Lupia, Michela; Cavallaro, Ugo; Pasini, Diego; Calado, Dinis P.

    2018-01-01

    Rationale: The mechanistic foundation of vascular maturation is still largely unknown. Several human pathologies are characterized by deregulated angiogenesis and unstable blood vessels. Solid tumors, for instance, get their nourishment from newly formed structurally abnormal vessels which present wide and irregular interendothelial junctions. Expression and clustering of the main endothelial-specific adherens junction protein, VEC (vascular endothelial cadherin), upregulate genes with key roles in endothelial differentiation and stability. Objective: We aim at understanding the molecular mechanisms through which VEC triggers the expression of a set of genes involved in endothelial differentiation and vascular stabilization. Methods and Results: We compared a VEC-null cell line with the same line reconstituted with VEC wild-type cDNA. VEC expression and clustering upregulated endothelial-specific genes with key roles in vascular stabilization including claudin-5, vascular endothelial-protein tyrosine phosphatase (VE-PTP), and von Willebrand factor (vWf). Mechanistically, VEC exerts this effect by inhibiting polycomb protein activity on the specific gene promoters. This is achieved by preventing nuclear translocation of FoxO1 (Forkhead box protein O1) and β-catenin, which contribute to PRC2 (polycomb repressive complex-2) binding to promoter regions of claudin-5, VE-PTP, and vWf. VEC/β-catenin complex also sequesters a core subunit of PRC2 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, preventing its nuclear translocation. Inhibition of Ezh2/VEC association increases Ezh2 recruitment to claudin-5, VE-PTP, and vWf promoters, causing gene downregulation. RNA sequencing comparison of VEC-null and VEC-positive cells suggested a more general role of VEC in activating endothelial genes and triggering a vascular stability-related gene expression program. In pathological angiogenesis of human ovarian carcinomas, reduced VEC expression paralleled decreased

  1. VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression.

    Science.gov (United States)

    Morini, Marco F; Giampietro, Costanza; Corada, Monica; Pisati, Federica; Lavarone, Elisa; Cunha, Sara I; Conze, Lei L; O'Reilly, Nicola; Joshi, Dhira; Kjaer, Svend; George, Roger; Nye, Emma; Ma, Anqi; Jin, Jian; Mitter, Richard; Lupia, Michela; Cavallaro, Ugo; Pasini, Diego; Calado, Dinis P; Dejana, Elisabetta; Taddei, Andrea

    2018-01-19

    The mechanistic foundation of vascular maturation is still largely unknown. Several human pathologies are characterized by deregulated angiogenesis and unstable blood vessels. Solid tumors, for instance, get their nourishment from newly formed structurally abnormal vessels which present wide and irregular interendothelial junctions. Expression and clustering of the main endothelial-specific adherens junction protein, VEC (vascular endothelial cadherin), upregulate genes with key roles in endothelial differentiation and stability. We aim at understanding the molecular mechanisms through which VEC triggers the expression of a set of genes involved in endothelial differentiation and vascular stabilization. We compared a VEC-null cell line with the same line reconstituted with VEC wild-type cDNA. VEC expression and clustering upregulated endothelial-specific genes with key roles in vascular stabilization including claudin-5 , vascular endothelial-protein tyrosine phosphatase ( VE-PTP ), and von Willebrand factor ( vWf ). Mechanistically, VEC exerts this effect by inhibiting polycomb protein activity on the specific gene promoters. This is achieved by preventing nuclear translocation of FoxO1 (Forkhead box protein O1) and β-catenin, which contribute to PRC2 (polycomb repressive complex-2) binding to promoter regions of claudin-5 , VE-PTP , and vWf . VEC/β-catenin complex also sequesters a core subunit of PRC2 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, preventing its nuclear translocation. Inhibition of Ezh2/VEC association increases Ezh2 recruitment to claudin-5 , VE-PTP , and vWf promoters, causing gene downregulation. RNA sequencing comparison of VEC-null and VEC-positive cells suggested a more general role of VEC in activating endothelial genes and triggering a vascular stability-related gene expression program. In pathological angiogenesis of human ovarian carcinomas, reduced VEC expression paralleled decreased levels of claudin-5 and VE-PTP. These

  2. Verifying SeVeCom Using Set-based Abstraction

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander; Modesti, Paolo

    We formally analyze the Secure Vehicle Communication system developed by the EU-project SeVeCom, using the AIF framework which is based on a novel set-abstraction technique. The model involves the hardware security modules (HSMs) of a number of cars, a certification authority, and the protocols...... executed between them. Each participant stores a database of keys that can be added or deleted depending on the different operations. The AIF-framework allows us to model and automatically analyze such databases with- out bounding the number of steps that the system can make and, in contrast to previous...

  3. Verifying SeVeCom Using Set-based Abstraction

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander; Modesti, Paolo

    2011-01-01

    We formally analyze the Secure Vehicle Communication system developed by the EU-project SeVeCom, using the AIF framework which is based on a novel set-abstraction technique. The model involves the hardware security modules (HSMs) of a number of cars, a certication authority, and the protocols...... executed between them. Each participant stores a database of keys that can be added or deleted depending on the dierent operations. The AIF-framework allows us to model and automatically analyze such databases with- out bounding the number of steps that the system can make and, in contrast to previous...

  4. Tuberculosis remains a challenge despite economic growth in Panama.

    Science.gov (United States)

    Tarajia, M; Goodridge, A

    2014-03-01

    Tuberculosis (TB) is a disease associated with inequality, and wise investment of economic resources is considered critical to its control. Panama has recently secured its status as an upper-middle-income country with robust economic growth. However, the prioritisation of resources for TB control remains a major challenge. In this article, we highlight areas that urgently require action to effectively reduce TB burden to minimal levels. Our conclusions suggest the need for fund allocation and a multidisciplinary approach to ensure prompt laboratory diagnosis, treatment assurance and workforce reinforcement, complemented by applied and operational research, development and innovation.

  5. Yellow Fever Remains a Potential Threat to Public Health.

    Science.gov (United States)

    Vasconcelos, Pedro F C; Monath, Thomas P

    2016-08-01

    Yellow fever (YF) remains a serious public health threat in endemic countries. The recent re-emergence in Africa, initiating in Angola and spreading to Democratic Republic of Congo and Uganda, with imported cases in China and Kenya is of concern. There is such a shortage of YF vaccine in the world that the World Health Organization has proposed the use of reduced doses (1/5) during emergencies. In this short communication, we discuss these and other problems including the risk of spread of YF to areas free of YF for decades or never before affected by this arbovirus disease.

  6. The Artificial Leaf: Recent Progress and Remaining Challenges

    Directory of Open Access Journals (Sweden)

    Mark D Symes

    2016-12-01

    Full Text Available The prospect of a device that uses solar energy to split water into H2 and O2 is highly attractive in terms of producing hydrogen as a carbon-neutral fuel. In this mini review, key research milestones that have been reached in this field over the last two decades will be discussed, with special focus on devices that use earth-abundant materials. Finally, the remaining challenges in the development of such “artificial leaves” will be highlighted.

  7. Leprosy: ancient disease remains a public health problem nowadays.

    Science.gov (United States)

    Noriega, Leandro Fonseca; Chiacchio, Nilton Di; Noriega, Angélica Fonseca; Pereira, Gilmayara Alves Abreu Maciel; Vieira, Marina Lino

    2016-01-01

    Despite being an ancient disease, leprosy remains a public health problem in several countries -particularly in India, Brazil and Indonesia. The current operational guidelines emphasize the evaluation of disability from the time of diagnosis and stipulate as fundamental principles for disease control: early detection and proper treatment. Continued efforts are needed to establish and improve quality leprosy services. A qualified primary care network that is integrated into specialized service and the development of educational activities are part of the arsenal in the fight against the disease, considered neglected and stigmatizing.

  8. Studies on protozoa in ancient remains - A Review

    Directory of Open Access Journals (Sweden)

    Liesbeth Frías

    2013-02-01

    Full Text Available Paleoparasitological research has made important contributions to the understanding of parasite evolution and ecology. Although parasitic protozoa exhibit a worldwide distribution, recovering these organisms from an archaeological context is still exceptional and relies on the availability and distribution of evidence, the ecology of infectious diseases and adequate detection techniques. Here, we present a review of the findings related to protozoa in ancient remains, with an emphasis on their geographical distribution in the past and the methodologies used for their retrieval. The development of more sensitive detection methods has increased the number of identified parasitic species, promising interesting insights from research in the future.

  9. Encephalitozoon cuniculi in Raw Cow's Milk Remains Infectious After Pasteurization.

    Science.gov (United States)

    Kváč, Martin; Tomanová, Vendula; Samková, Eva; Koubová, Jana; Kotková, Michaela; Hlásková, Lenka; McEvoy, John; Sak, Bohumil

    2016-02-01

    This study describes the prevalence of Encephalitozoon cuniculi in raw cow's milk and evaluates the effect of different milk pasteurization treatments on E. cuniculi infectivity for severe combined immunodeficient (SCID) mice. Using a nested polymerase chain reaction approach, 1 of 50 milking cows was found to repeatedly shed E. cuniculi in its feces and milk. Under experimental conditions, E. cuniculi spores in milk remained infective for SCID mice following pasteurization treatments at 72 °C for 15 s or 85 °C for 5 s. Based on these findings, pasteurized cow's milk should be considered a potential source of E. cuniculi infection in humans.

  10. Fossil human remains from Bolomor Cave (Valencia, Spain).

    Science.gov (United States)

    Arsuaga, Juan Luis; Fernández Peris, Josep; Gracia-Téllez, Ana; Quam, Rolf; Carretero, José Miguel; Barciela González, Virginia; Blasco, Ruth; Cuartero, Felipe; Sañudo, Pablo

    2012-05-01

    Systematic excavations carried out since 1989 at Bolomor Cave have led to the recovery of four Pleistocene human fossil remains, consisting of a fibular fragment, two isolated teeth, and a nearly complete adult parietal bone. All of these specimens date to the late Middle and early Late Pleistocene (MIS 7-5e). The fibular fragment shows thick cortical bone, an archaic feature found in non-modern (i.e. non-Homo sapiens) members of the genus Homo. Among the dental remains, the lack of a midtrigonid crest in the M(1) represents a departure from the morphology reported for the majority of Neandertal specimens, while the large dimensions and pronounced shoveling of the marginal ridges in the C(1) are similar to other European Middle and late Pleistocene fossils. The parietal bone is very thick, with dimensions that generally fall above Neandertal fossils and resemble more closely the Middle Pleistocene Atapuerca (SH) adult specimens. Based on the presence of archaic features, all the fossils from Bolomor are attributed to the Neandertal evolutionary lineage. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Determination of Remaining Useful Life of Gas Turbine Blade

    Directory of Open Access Journals (Sweden)

    Meor Said Mior Azman

    2016-01-01

    Full Text Available The aim of this research is to determine the remaining useful life of gas turbine blade, using service-exposed turbine blades. This task is performed using Stress Rupture Test (SRT under accelerated test conditions where the applied stresses to the specimen is between 400 MPa to 600 MPa and the test temperature is 850°C. The study will focus on the creep behaviour of the 52000 hours service-exposed blades, complemented with creep-rupture modelling using JMatPro software and microstructure examination using optical microscope. The test specimens, made up of Ni-based superalloy of the first stage turbine blades, are machined based on International Standard (ISO 24. The results from the SRT will be analyzed using these two main equations – Larson-Miller Parameter and Life Fraction Rule. Based on the results of the remaining useful life analysis, the 52000h service-exposed blade has the condition to operate in the range of another 4751 hr to 18362 hr. The microstructure examinations shows traces of carbide precipitation that deteriorate the grain boundaries that occurs during creep process. Creep-rupture life modelling using JMatPro software has shown good agreement with the accelerated creep rupture test with minimal error.

  12. A method for defleshing human remains using household bleach.

    Science.gov (United States)

    Mann, Robert W; Berryman, Hugh E

    2012-03-01

    Medical examiners and forensic anthropologists are often faced with the difficult task of removing soft tissue from the human skeleton without damaging the bones, teeth and, in some cases, cartilage. While there are a number of acceptable methods that can be used to remove soft tissue including macerating in water, simmering or boiling, soaking in ammonia, removing with scissors, knife, scalpel or stiff brush, and dermestid beetles, each has its drawback in time, safety, or potential to damage bone. This technical report using the chest plate of a stabbing victim presents a safe and effective alternative method for removing soft tissue from human remains, in particular the chest plate, following autopsy, without damaging or separating the ribs, sternum, and costal cartilage. This method can be used to reveal subtle blunt force trauma to bone, slicing and stabbing injuries, and other forms of trauma obscured by overlying soft tissue. Despite the published cautionary notes, when done properly household bleach (3-6% sodium hypochlorite) is a quick, safe, and effective method for examining cartilage and exposing skeletal trauma by removing soft tissue from human skeletal remains. 2011 American Academy of Forensic Sciences. Published 2011. This article is a U.S. Government work and is in the public domain in the U.S.A.

  13. Duplex Alu Screening for Degraded DNA of Skeletal Human Remains

    Directory of Open Access Journals (Sweden)

    Fabian Haß

    2017-10-01

    Full Text Available The human-specific Alu elements, belonging to the class of Short INterspersed Elements (SINEs, have been shown to be a powerful tool for population genetic studies. An earlier study in this department showed that it was possible to analyze Alu presence/absence in 3000-year-old skeletal human remains from the Bronze Age Lichtenstein cave in Lower Saxony, Germany. We developed duplex Alu screening PCRs with flanking primers for two Alu elements, each combined with a single internal Alu primer. By adding an internal primer, the approximately 400–500 bp presence signals of Alu elements can be detected within a range of less than 200 bp. Thus, our PCR approach is suited for highly fragmented ancient DNA samples, whereas NGS analyses frequently are unable to handle repetitive elements. With this analysis system, we examined remains of 12 individuals from the Lichtenstein cave with different degrees of DNA degradation. The duplex PCRs showed fully informative amplification results for all of the chosen Alu loci in eight of the 12 samples. Our analysis system showed that Alu presence/absence analysis is possible in samples with different degrees of DNA degradation and it reduces the amount of valuable skeletal material needed by a factor of four, as compared with a singleplex approach.

  14. On use of radial evanescence remain term in kinematic hardening

    International Nuclear Information System (INIS)

    Geyer, P.

    1995-10-01

    A fine modelling of the material' behaviour can be necessary to study the mechanical strength of nuclear power plant' components under cyclic loads. Ratchetting is one of the last phenomena for which numerical models have to be improved. We discuss in this paper on use of radial evanescence remain term in kinematic hardening to improve the description of ratchetting in biaxial loading tests. It's well known that Chaboche elastoplastic model with two non linear kinematic hardening variables initially proposed by Armstrong and Frederick, usually over-predicts accumulation of ratchetting strain. Burlet and Cailletaud proposed in 1987 a non linear kinematic rule with a radial evanescence remain term. The two models lead to identical formulation for proportional loadings. In the case of a biaxial loading test (primary+secondary loading), Burlet and Cailletaud model leads to accommodation, when Chaboche one's leads to ratchetting with a constant increment of strain. So we can have an under-estimate with the first model and an over-estimate with the second. An easy method to improve the description of ratchetting is to combine the two kinematic rules. Such an idea is already used by Delobelle in his model. With analytical results in the case of tension-torsion tests, we show in a first part of the paper, the interest of radial evanescence remain term in the non linear kinematic rule to describe ratchetting: we give the conditions to get adaptation, accommodation or ratchetting and the value of the strain increment in the last case. In the second part of the paper, we propose to modify the elastoplastic Chaboche model by coupling the two types of hardening by means of two scalar parameters which can be identified independently on biaxial loading tests. Identification of these two parameters returns to speculate on the directions of strain in order to adjust the ratchetting to experimental observations. We use the experimental results on the austenitic steel 316L at room

  15. Highly efficient DNA extraction method from skeletal remains

    Directory of Open Access Journals (Sweden)

    Irena Zupanič Pajnič

    2011-03-01

    Full Text Available Background: This paper precisely describes the method of DNA extraction developed to acquire high quality DNA from the Second World War skeletal remains. The same method is also used for molecular genetic identification of unknown decomposed bodies in routine forensic casework where only bones and teeth are suitable for DNA typing. We analysed 109 bones and two teeth from WWII mass graves in Slovenia. Methods: We cleaned the bones and teeth, removed surface contaminants and ground the bones into powder, using liquid nitrogen . Prior to isolating the DNA in parallel using the BioRobot EZ1 (Qiagen, the powder was decalcified for three days. The nuclear DNA of the samples were quantified by real-time PCR method. We acquired autosomal genetic profiles and Y-chromosome haplotypes of the bones and teeth with PCR amplification of microsatellites, and mtDNA haplotypes 99. For the purpose of traceability in the event of contamination, we prepared elimination data bases including genetic profiles of the nuclear and mtDNA of all persons who have been in touch with the skeletal remains in any way. Results: We extracted up to 55 ng DNA/g of the teeth, up to 100 ng DNA/g of the femurs, up to 30 ng DNA/g of the tibias and up to 0.5 ng DNA/g of the humerus. The typing of autosomal and YSTR loci was successful in all of the teeth, in 98 % dekalof the femurs, and in 75 % to 81 % of the tibias and humerus. The typing of mtDNA was successful in all of the teeth, and in 96 % to 98 % of the bones. Conclusions: We managed to obtain nuclear DNA for successful STR typing from skeletal remains that were over 60 years old . The method of DNA extraction described here has proved to be highly efficient. We obtained 0.8 to 100 ng DNA/g of teeth or bones and complete genetic profiles of autosomal DNA, Y-STR haplotypes, and mtDNA haplotypes from only 0.5g bone and teeth samples.

  16. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier d...

  17. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier ...

  18. VARLIK VERGİSİ VE MERSİN UYGULAMASI

    OpenAIRE

    ÇANAK, Erdem

    2016-01-01

    Türkiye, İkinci Dünya Savaşı’na girmemekle birlikte savaşın bütün sıkıntılarını yaşamıştır. Hatta bu sırada 1 milyona yakın vatandaşını da silâhaltına almıştır. Ülkenin çalışan ve üretim yapan nüfusunun silâhaltına alınması ise üretimde ciddi düşüşlere sebebiyet vermiştir. Bunun yanı sıra savaşın neden olduğu iktisadi sıkıntıların etkisiyle enflasyon yükselmiş, karaborsa ve vurgunculuk artmıştır. Bu durumdan en çok istifade edenler ise büyük toprak sahibi çiftçiler ile ticaretle iştigal eden ...

  19. Türev piyasaları ve vergilendirilmesi

    OpenAIRE

    İşler, İsmail; Utku, Mehmet

    2015-01-01

    Türev piyasaları kavramı, vadeli işlem sözleşmeleri (forward, futures), opsiyon sözleşmeleri, swap sözleşmeleri ve aracı kuruluş varantları işlemlerinin tamamını içermektedir. Bu tür işlemler vadeli işlemlerdir. Vadeli işlemlerin ortak özelliği, ilerideki bir tarihte teslimatı yapılmak üzere herhangi bir malın veya finansal aracın, bugünden alım satımının yapılmasıdır. Bu çalışmada türev araçların tanımları ve vergilendirilmeleri örneklerle açıklanacaktır. The term derivatives market invol...

  20. TMI in perspective: reactor containment stands up, difficult decisions remain

    International Nuclear Information System (INIS)

    Corey, G.R.

    1979-01-01

    Commonwealth Edison Co. is increasing its commitment to nuclear energy after reviewing the performance of the Three Mile Island reactor containment systems. Both the reactor vessel and the secondary containment remained intact and no radiation was reported in the soil or water. The public discussion of energy options which followed the accident will benefit both the public and technical community even if there is a temporary slowdown in nuclear power development. The realities of energy supplies have become evident; i.e., that nuclear and coal are the only available options for the short-term. The discussion should also lead to better personnel training, regulatory reforms, risk-sharing insurance, and international standards. The public hysteria triggered by the accident stemmed partly from the combination of unfortunate incidents and the media coverage, which led to hasty conclusions

  1. Oldest Directly Dated Remains of Sheep in China

    Science.gov (United States)

    Dodson, John; Dodson, Eoin; Banati, Richard; Li, Xiaoqiang; Atahan, Pia; Hu, Songmei; Middleton, Ryan J.; Zhou, Xinying; Nan, Sun

    2014-11-01

    The origins of domesticated sheep (Ovis sp.) in China remain unknown. Previous workers have speculated that sheep may have been present in China up to 7000 years ago, however many claims are based on associations with archaeological material rather than independent dates on sheep material. Here we present 7 radiocarbon dates on sheep bone from Inner Mongolia, Ningxia and Shaanxi provinces. DNA analysis on one of the bones confirms it is Ovis sp. The oldest ages are about 4700 to 4400 BCE and are thus the oldest objectively dated Ovis material in eastern Asia. The graphitisised bone collagen had δ13C values indicating some millet was represented in the diet. This probably indicates sheep were in a domestic setting where millet was grown. The younger samples had δ13C values indicating that even more millet was in the diet, and this was likely related to changes in foddering practices

  2. On use of radial evanescence remain term in kinematic hardening

    International Nuclear Information System (INIS)

    Geyer, P.

    1995-01-01

    This paper presents the interest which lies in non-linear kinematic hardening rule with radial evanescence remain term as proposed for modelling multiaxial ratchetting. From analytical calculations in the case of the tension/torsion test, this ratchetting is compared with that proposed by Armstrong and Frederick. A modification is then proposed for Chaboche's elastoplastic model with two non-linear kinematic variables, by coupling the two types of hardening by means of two scalar parameters. Identification of these two parameters returns to speculate on the directions of strain in order to adjust the ratchetting to experimental observations. Using biaxial ratchetting tests on stainless steel 316 L specimens at ambient temperature, it is shown that satisfactory modelling of multiaxial ratchetting is obtained. (author). 4 refs., 5 figs

  3. Psychotherapy for Borderline Personality Disorder: Progress and Remaining Challenges.

    Science.gov (United States)

    Links, Paul S; Shah, Ravi; Eynan, Rahel

    2017-03-01

    The main purpose of this review was to critically evaluate the literature on psychotherapies for borderline personality disorder (BPD) published over the past 5 years to identify the progress with remaining challenges and to determine priority areas for future research. A systematic review of the literature over the last 5 years was undertaken. The review yielded 184 relevant abstracts, and after applying inclusion criteria, 16 articles were fully reviewed based on the articles' implications for future research and/or clinical practice. Our review indicated that patients with various severities benefited from psychotherapy; more intensive therapies were not significantly superior to less intensive therapies; enhancing emotion regulation processes and fostering more coherent self-identity were important mechanisms of change; therapies had been extended to patients with BPD and posttraumatic stress disorder; and more research was needed to be directed at functional outcomes.

  4. [Alcohol and work: remaining sober and return to work].

    Science.gov (United States)

    Vittadini, G; Bandirali, M

    2007-01-01

    One of the most complex alcohol-driven problems is the job loss and the subsequent attempts to return to a professional activity. In order to better understand the issue, an epidemiologic investigation was carried out on a group of 162 alcoholics whilst hospitalised in a specialised clinic. The outcome shows the importance of remaining sober to keep or to be returned to one's own job. Unfortunately, local resources at hand, first of all joining an auto-mutual-help group, re still too little known and thus clearly underemployed. Therefore, an informative action within companies is highly desirable. Those alcoholics suffering from serious illnesses, especially mental ones represent a different issue. For these people a higher involvement of public authorities is desirable in creating protected job openings.

  5. Differential Decomposition Among Pig, Rabbit, and Human Remains.

    Science.gov (United States)

    Dautartas, Angela; Kenyhercz, Michael W; Vidoli, Giovanna M; Meadows Jantz, Lee; Mundorff, Amy; Steadman, Dawnie Wolfe

    2018-03-30

    While nonhuman animal remains are often utilized in forensic research to develop methods to estimate the postmortem interval, systematic studies that directly validate animals as proxies for human decomposition are lacking. The current project compared decomposition rates among pigs, rabbits, and humans at the University of Tennessee's Anthropology Research Facility across three seasonal trials that spanned nearly 2 years. The Total Body Score (TBS) method was applied to quantify decomposition changes and calculate the postmortem interval (PMI) in accumulated degree days (ADD). Decomposition trajectories were analyzed by comparing the estimated and actual ADD for each seasonal trial and by fuzzy cluster analysis. The cluster analysis demonstrated that the rabbits formed one group while pigs and humans, although more similar to each other than either to rabbits, still showed important differences in decomposition patterns. The decomposition trends show that neither nonhuman model captured the pattern, rate, and variability of human decomposition. © 2018 American Academy of Forensic Sciences.

  6. Premortal data in the process of skeletal remains identification

    Directory of Open Access Journals (Sweden)

    Marinković Nadica

    2012-01-01

    Full Text Available Background/Aim. The basic task of a forensic examiner during the exhumation of mass graves or in mass accidents is to establish identity of a person. The results obtained through these procedures depend on the level of perceptibility of post mortal changes and they are compared with premortal data obtained from family members of those missing or killed. Experience with exhumations has shown significant differences between the results obtained through exhumation and the premortal data. The aim of the study was to suggest the existance of the difference between premortal data and the results obtained by exhumation regarding the some parameters, as well as to direct premortal data colection to the specific skeletal forms. Methods. We performed comparative analysis of the results of exhumation of skeletal remains in a mass grave and the premortal data concerning the identified persons. The least number of individuals in this mass grave was calculated according to the upper parts of the right femur and it helped in calculating the smallest number of individuals in mass graves to be 48. A total of 27 persons were identified. Sex was determined by metrics and morphology of the pelvis. Personal age in the moment of death was determined by morphology features of groin symphisis and morphology of sternal edge of ribs and other parts of scelets observations. The hight was calculated as average results of length of long bones and Rollet coefficients. Results. There was a complete match in terms of sex and age matched within an interval that could be established based on the skeletal remains. All the other parameters were different, however, which made identification significantly more difficult. Conclusion. The premortal data is an important element of identification process and it should be obtained by the forensic doctor and directed towards more detailed examination of the skeletal system.

  7. Reidentification of avian embryonic remains from the cretaceous of mongolia.

    Science.gov (United States)

    Varricchio, David J; Balanoff, Amy M; Norell, Mark A

    2015-01-01

    Embryonic remains within a small (4.75 by 2.23 cm) egg from the Late Cretaceous, Mongolia are here re-described. High-resolution X-ray computed tomography (HRCT) was used to digitally prepare and describe the enclosed embryonic bones. The egg, IGM (Mongolian Institute for Geology, Ulaanbaatar) 100/2010, with a three-part shell microstructure, was originally assigned to Neoceratopsia implying extensive homoplasy among eggshell characters across Dinosauria. Re-examination finds the forelimb significantly longer than the hindlimbs, proportions suggesting an avian identification. Additional, postcranial apomorphies (strut-like coracoid, cranially located humeral condyles, olecranon fossa, slender radius relative to the ulna, trochanteric crest on the femur, and ulna longer than the humerus) identify the embryo as avian. Presence of a dorsal coracoid fossa and a craniocaudally compressed distal humerus with a strongly angled distal margin support a diagnosis of IGM 100/2010 as an enantiornithine. Re-identification eliminates the implied homoplasy of this tri-laminate eggshell structure, and instead associates enantiornithine birds with eggshell microstructure composed of a mammillary, squamatic, and external zones. Posture of the embryo follows that of other theropods with fore- and hindlimbs folded parallel to the vertebral column and the elbow pointing caudally just dorsal to the knees. The size of the egg and embryo of IGM 100/2010 is similar to the two other Mongolian enantiornithine eggs. Well-ossified skeletons, as in this specimen, characterize all known enantiornithine embryos suggesting precocial hatchlings, comparing closely to late stage embryos of modern precocial birds that are both flight- and run-capable upon hatching. Extensive ossification in enantiornithine embryos may contribute to their relatively abundant representation in the fossil record. Neoceratopsian eggs remain unrecognized in the fossil record.

  8. Reidentification of avian embryonic remains from the cretaceous of mongolia.

    Directory of Open Access Journals (Sweden)

    David J Varricchio

    Full Text Available Embryonic remains within a small (4.75 by 2.23 cm egg from the Late Cretaceous, Mongolia are here re-described. High-resolution X-ray computed tomography (HRCT was used to digitally prepare and describe the enclosed embryonic bones. The egg, IGM (Mongolian Institute for Geology, Ulaanbaatar 100/2010, with a three-part shell microstructure, was originally assigned to Neoceratopsia implying extensive homoplasy among eggshell characters across Dinosauria. Re-examination finds the forelimb significantly longer than the hindlimbs, proportions suggesting an avian identification. Additional, postcranial apomorphies (strut-like coracoid, cranially located humeral condyles, olecranon fossa, slender radius relative to the ulna, trochanteric crest on the femur, and ulna longer than the humerus identify the embryo as avian. Presence of a dorsal coracoid fossa and a craniocaudally compressed distal humerus with a strongly angled distal margin support a diagnosis of IGM 100/2010 as an enantiornithine. Re-identification eliminates the implied homoplasy of this tri-laminate eggshell structure, and instead associates enantiornithine birds with eggshell microstructure composed of a mammillary, squamatic, and external zones. Posture of the embryo follows that of other theropods with fore- and hindlimbs folded parallel to the vertebral column and the elbow pointing caudally just dorsal to the knees. The size of the egg and embryo of IGM 100/2010 is similar to the two other Mongolian enantiornithine eggs. Well-ossified skeletons, as in this specimen, characterize all known enantiornithine embryos suggesting precocial hatchlings, comparing closely to late stage embryos of modern precocial birds that are both flight- and run-capable upon hatching. Extensive ossification in enantiornithine embryos may contribute to their relatively abundant representation in the fossil record. Neoceratopsian eggs remain unrecognized in the fossil record.

  9. Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients

    Science.gov (United States)

    Talbert, Erin E.; Lewis, Heather L.; Farren, Matthew R.; Ramsey, Mitchell L.; Chakedis, Jeffery M.; Rajasekera, Priyani; Haverick, Ericka; Sarna, Angela; Bloomston, Mark; Pawlik, Timothy M.; Zimmers, Teresa A.; Lesinski, Gregory B.; Hart, Phil A.; Dillhoff, Mary E.; Schmidt, Carl R.

    2018-01-01

    Abstract Background Cancer‐associated wasting, termed cancer cachexia, has a profound effect on the morbidity and mortality of cancer patients but remains difficult to recognize and diagnose. While increases in circulating levels of a number of inflammatory cytokines have been associated with cancer cachexia, these associations were generally made in patients with advanced disease and thus may be associated with disease progression rather than directly with the cachexia syndrome. Thus, we sought to assess potential biomarkers of cancer‐induced cachexia in patients with earlier stages of disease. Methods A custom multiplex array was used to measure circulating levels of 25 soluble factors from 70 pancreatic cancer patients undergoing attempted tumour resections. A high‐sensitivity multiplex was used for increased sensitivity for nine cytokines. Results Resectable pancreatic cancer patients with cachexia had low levels of canonical pro‐inflammatory cytokines including interleukin‐6 (IL‐6), interleukin‐1β (IL‐1β), interferon‐γ (IFN‐γ), and tumour necrosis factor (TNF). Even in our more sensitive analysis, these cytokines were not associated with cancer cachexia. Of the 25 circulating factors tested, only monocyte chemoattractant protein‐1 (MCP‐1) was increased in treatment‐naïve cachectic patients compared with weight stable patients and identified as a potential biomarker for cancer cachexia. Although circulating levels of leptin and granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) were found to be decreased in the same cohort of treatment‐naïve cachectic patients, these factors were closely associated with body mass index, limiting their utility as cancer cachexia biomarkers. Conclusions Unlike in advanced disease, it is possible that cachexia in patients with resectable pancreatic cancer is not associated with high levels of classical markers of systemic inflammation. However, cachectic, treatment‐naïve patients

  10. Türkiye’de Üretilen Kuru fasulyelerin Pişme Kalitesi ve Kompozisyonu (İngilizce

    Directory of Open Access Journals (Sweden)

    Recai Ercan

    2015-02-01

    Full Text Available Türkiye’de 2 bölgede yetiştirilen 8 kuru fasulye genotiplerinin fiziksel kriterleri ve pişme kalitesi ile mineral madde, tiyamin ve riboflavin miktarları saptanmıştır. Genotip ve yetiştirme lokasyonları ile bunların interaksiyonu bütün kriterleri önemli düzeyde etkilemiştir (P<0.05. Kuru ve yaş tohum ağırlığı, şişme kapasitesi ve indeksi, hidrasyon kapasitesi, kuru ve yaş hacim, kuru ve yaş pişme süresi ile Cu, Mn ve Na miktarları başlıca genotipden etkilenmiştir. Zn ve P miktarı ise çevreden etkilenmiştir. Kuru ve yaş tohum ağırlığı, kuru ve yaş hacim, hidrasyon ve şişme kapasitesi önemli düzeyde kuru ve yaş pişme süresi ile ilişkili olmuştur.

  11. Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora Türlerinin Kimyasal İçeriği ve Fenolik Ekstraktiflerinin İncelenmesi

    Directory of Open Access Journals (Sweden)

    Samim YAŞAR

    2016-05-01

    Full Text Available Bu çalışmada Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora bitkilerinden alınan örneklerde kimyasal bileşim ve fenolik ekstraktifler incelenmiştir. Bu türlerin endüstriyel anlamda oduna alternatif olabilirliği ve antioksidan üretiminde hammadde olarak kullanılabilirliği değerlendirilmiştir. Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora bitkilerine ait örneklerde holoselüloz, selüloz, α-selüloz, lignin ve kül miktarları ile etanol siklohekzan, soğuk su, sıcak su ve %1 NaOH çözünürlükleri sırasıyla %73.26-76.32, %53.58-54.52, %43.28-44.73, %20.39-21.27, %2.12-2.79, %2.49-2.71, %9.67-11.70, %10.77-12.42 ve %21.77-24.48 aralığında bulunmuştur. HPLC analizleri toplam fenolik madde miktarının Vitex agnus-castus’da (2.09 mg/g, Tamarix parviflora’da (1.05 mg/g ve Laurus nobilis’de (0.58 mg/g olduğunu göstermiştir. Laurus nobilis’te en yüksek miktardaki fenolik ekstraktif madde epikateşin (0.23 mg/g ve Tamarix parviflora’da gallik asit (0.17 mg/g olarak belirlenmiş, Vitex agnus-castus’da ise p-hidroksibenzoik asit (0.95 mg/g olarak tespit edilmiştir. Elde edilen sonuçlar, çalışma konusu bitkilerin iğne yapraklı ve yapraklı türlerle karşılaştırılabilir düzeyde olduğunu göstermiş olup, söz konusu maki türlerinin orman ürünleri endüstrisinde ve ticari antioksidan üretiminde hammadde olarak kullanılabileceklerini ortaya koymuştur.

  12. Future Remains: Industrial Heritage at the Hanford Plutonium Works

    Science.gov (United States)

    Freer, Brian

    This dissertation argues that U.S. environmental and historic preservation regulations, industrial heritage projects, history, and art only provide partial frameworks for successfully transmitting an informed story into the long range future about nuclear technology and its related environmental legacy. This argument is important because plutonium from nuclear weapons production is toxic to humans in very small amounts, threatens environmental health, has a half-life of 24, 110 years and because the industrial heritage project at Hanford is the first time an entire U.S. Department of Energy weapons production site has been designated a U.S. Historic District. This research is situated within anthropological interest in industrial heritage studies, environmental anthropology, applied visual anthropology, as well as wider discourses on nuclear studies. However, none of these disciplines is really designed or intended to be a completely satisfactory frame of reference for addressing this perplexing challenge of documenting and conveying an informed story about nuclear technology and its related environmental legacy into the long range future. Others have thought about this question and have made important contributions toward a potential solution. Examples here include: future generations movements concerning intergenerational equity as evidenced in scholarship, law, and amongst Native American groups; Nez Perce and Confederated Tribes of the Umatilla Indian Reservation responses to the Hanford End State Vision and Hanford's Canyon Disposition Initiative; as well as the findings of organizational scholars on the advantages realized by organizations that have a long term future perspective. While these ideas inform the main line inquiry of this dissertation, the principal approach put forth by the researcher of how to convey an informed story about nuclear technology and waste into the long range future is implementation of the proposed Future Remains clause, as

  13. Defense.gov Special Report: V-E Day - 70th Anniversary

    Science.gov (United States)

    are strong united we will win WWII United Nations4 United We Win WWII United We can't win without them Historic Aircraft to Conduct V-E Day Flyover America will remember the millions who helped make possible 70th Anniversary in France Arsenal of Democracy Flyover Media Day V-E Day Veterans Profiles Charles

  14. Plasmodium vivax sporozoite challenge in malaria-naïve and semi-immune Colombian volunteers

    DEFF Research Database (Denmark)

    Arévalo-Herrera, Myriam; Forero-Peña, David A.; Rubiano, Kelly

    2014-01-01

    induced in naïve and semi-immune volunteers by infected mosquito bites was compared. Methods: Seven malaria-naïve and nine semi-immune Colombian adults (n = 16) were subjected to the bites of 2-4 P. vivax sporozoite-infected Anopheles mosquitoes. Parasitemia levels, malaria clinical manifestations...

  15. Building Students' Understanding of Quadratic Equation Concept Using Naïve Geometry

    Science.gov (United States)

    Fachrudin, Achmad Dhany; Putri, Ratu Ilma Indra; Darmawijoyo

    2014-01-01

    The purpose of this research is to know how Naïve Geometry method can support students' understanding about the concept of solving quadratic equations. In this article we will discuss one activities of the four activities we developed. This activity focused on how students linking the Naïve Geometry method with the solving of the quadratic…

  16. New Evidence Links Stellar Remains to Oldest Recorded Supernova

    Science.gov (United States)

    2006-09-01

    Recent observations have uncovered evidence that helps to confirm the identification of the remains of one of the earliest stellar explosions recorded by humans. The new study shows that the supernova remnant RCW 86 is much younger than previously thought. As such, the formation of the remnant appears to coincide with a supernova observed by Chinese astronomers in 185 A.D. The study used data from NASA's Chandra X-ray Observatory and the European Space Agency's XMM-Newton Observatory, "There have been previous suggestions that RCW 86 is the remains of the supernova from 185 A.D.," said Jacco Vink of University of Utrecht, the Netherlands, and lead author of the study. "These new X-ray data greatly strengthen the case." When a massive star runs out of fuel, it collapses on itself, creating a supernova that can outshine an entire galaxy. The intense explosion hurls the outer layers of the star into space and produces powerful shock waves. The remains of the star and the material it encounters are heated to millions of degrees and can emit intense X-ray radiation for thousands of years. Animation of a Massive Star Explosion Animation of a Massive Star Explosion In their stellar forensic work, Vink and colleagues studied the debris in RCW 86 to estimate when its progenitor star originally exploded. They calculated how quickly the shocked, or energized, shell is moving in RCW 86, by studying one part of the remnant. They combined this expansion velocity with the size of the remnant and a basic understanding of how supernovas expand to estimate the age of RCW 86. "Our new calculations tell us the remnant is about 2,000 years old," said Aya Bamba, a coauthor from the Institute of Physical and Chemical Research (RIKEN), Japan. "Previously astronomers had estimated an age of 10,000 years." The younger age for RCW 86 may explain an astronomical event observed almost 2000 years ago. In 185 AD, Chinese astronomers (and possibly the Romans) recorded the appearance of a new

  17. Spot market activity remains weak as prices continue to fall

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    A summary of financial data for the uranium spot market in November 1996 is provided. Price ranges for the restricted and unrestricted markets, conversion, and separative work are listed, and total market volume and new contracts are noted. Transactions made are briefly described. Deals made and pending in the spot concentrates, medium and long-term, conversion, and markets are listed for U.S. and non-U.S. buyers. Spot market activity increased in November with just over 1.0 million lbs of U3O8 equivalent being transacted compared to October's total of 530,000 lbs of U3O8 equivalent. The restricted uranium spot market price range slipped from $15.50-$15.70/lb U3O8 last month to $14.85/lb - $15.25/lb U3O8 this month. The unrestricted uranium spot market price range also slipped to $14.85/lb - $15.00/lb this month from $15.00/lb - $15.45/lb in October. Spot prices for conversion and separative work units remained at their October levels

  18. Briquettes of plant remains from the greenhouses of Almeria (Spain)

    Energy Technology Data Exchange (ETDEWEB)

    Callejon-Ferre, A. J.; Lopez-Martinez, J. A.

    2009-07-01

    Since ancient times, plant biomass has been used as a primary fuel, and today, with the impending depletion of fossil fuels, these vegetal sources constitute a cleaner alternative and furthermore have a multitude of uses. The aim of the present study is to design a method of recycling and reuse of plant wastes from intensive agriculture under plastic, by manufacturing briquettes in an environmentally friendly manner. In Almeria (SE Spain), agriculture generates 769,500 t year{sup -}1 of plant remains from greenhouse-grown horticultural crops, a resource currently used for composting and for producing electricity.With the machinery and procedures of the present study, another potential use has been developed by detoxifying and eliminating the plastic wastes of the original biomass for the fabrication of briquettes for fireplaces. The results were slightly inferior to the commercial briquette from other non-horticultural plant materials (no forestry material), specifically 2512 kJ kg{sup -}1, in the least favourable case. On the contrary, the heating value with respect to the two charcoals was significantly lower, with a difference of 12,142 kJ kg{sup -}1. In conclusion; a procedure, applicable in ecological cultivation without agrochemicals or plastic cords, has been developed and tested to reuse and transform plant materials from intensive cultivation into a stable non-toxic product similar to composite logs, applicable in commercial settings or in residential fireplaces. (Author) 48 refs.

  19. Are the alleged remains of Johann Sebastian Bach authentic?

    Science.gov (United States)

    Zegers, Richard H C; Maas, Mario; Koopman, A Ton G; Maat, George J R

    2009-02-16

    A skeleton alleged to be that of Johann Sebastian Bach (1685-1750) was exhumed from a graveyard in Leipzig, Germany, in 1894, but its authenticity is not established. In 1895, anatomist Wilhelm His concluded from his examination of the skeleton and reconstruction of the face that it most likely belonged to Bach. In 1949, surgeon Wolfgang Rosenthal noticed exostoses on the skeleton and on x-rays of 11 living organists and proposed a condition, Organistenkrankheit, which he interpreted as evidence that the skeleton was Bach's. However, our critical assessment of the remains analysis raises doubts: the localisation of the grave was dubious, and the methods used by His to reconstruct the face are controversial. Also, our study of the pelvic x-rays of 12 living professional organists failed to find evidence for the existence of Organistenkrankheit. We believe it is unlikely that the skeleton is that of Bach; techniques such as DNA analysis might help resolve the question but, to date, church authorities have not approved their use on the skeleton.

  20. Carnivoran remains from the Malapa hominin site, South Africa.

    Directory of Open Access Journals (Sweden)

    Brian F Kuhn

    Full Text Available Recent discoveries at the new hominin-bearing deposits of Malapa, South Africa, have yielded a rich faunal assemblage associated with the newly described hominin taxon Australopithecus sediba. Dating of this deposit using U-Pb and palaeomagnetic methods has provided an age of 1.977 Ma, being one of the most accurately dated, time constrained deposits in the Plio-Pleistocene of southern Africa. To date, 81 carnivoran specimens have been identified at this site including members of the families Canidae, Viverridae, Herpestidae, Hyaenidae and Felidae. Of note is the presence of the extinct taxon Dinofelis cf. D. barlowi that may represent the last appearance date for this species. Extant large carnivores are represented by specimens of leopard (Panthera pardus and brown hyaena (Parahyaena brunnea. Smaller carnivores are also represented, and include the genera Atilax and Genetta, as well as Vulpes cf. V. chama. Malapa may also represent the first appearance date for Felis nigripes (Black-footed cat. The geochronological age of Malapa and the associated hominin taxa and carnivoran remains provide a window of research into mammalian evolution during a relatively unknown period in South Africa and elsewhere. In particular, the fauna represented at Malapa has the potential to elucidate aspects of the evolution of Dinofelis and may help resolve competing hypotheses about faunal exchange between East and Southern Africa during the late Pliocene or early Pleistocene.

  1. DNA Profiling Success Rates from Degraded Skeletal Remains in Guatemala.

    Science.gov (United States)

    Johnston, Emma; Stephenson, Mishel

    2016-07-01

    No data are available regarding the success of DNA Short Tandem Repeat (STR) profiling from degraded skeletal remains in Guatemala. Therefore, DNA profiling success rates relating to 2595 skeletons from eleven cases at the Forensic Anthropology Foundation of Guatemala (FAFG) are presented. The typical postmortem interval was 30 years. DNA was extracted from bone powder and amplified using Identifiler and Minifler. DNA profiling success rates differed between cases, ranging from 50.8% to 7.0%, the overall success rate for samples was 36.3%. The best DNA profiling success rates were obtained from femur (36.2%) and tooth (33.7%) samples. DNA profiles were significantly better from lower body bones than upper body bones (p = <0.0001). Bone samples from males gave significantly better profiles than samples from females (p = <0.0001). These results are believed to be related to bone density. The findings are important for designing forensic DNA sampling strategies in future victim recovery investigations. © 2016 American Academy of Forensic Sciences.

  2. Using contractors to decommission while remaining as licensee

    International Nuclear Information System (INIS)

    Rankine, A.

    1997-01-01

    Over the last few years the role of the United Kingdom Atomic Energy Authority (UKAEA) has changed from one involved in research and development in the field of nuclear power and associated technology, to one of managing the liabilities left over from its previous mission. This period has also seen two significant portions of the organization move to the private sector with sale of the Facilities Services Division to PROCORD and the privatization of AEA Technology. The new UKAEA is therefore a focused liabilities management organization, making the best use of expertise in the private sector in carrying out its mission, but retaining adequate internal resource and expertise to fulful its role and responsibilities as the licensee. UKAEA continues to be committed to giving the highest priority to meeting high standards of safety and environmental protection required of the holder of the Nuclear Site Licence under the Nuclear Installations Act. This paper describes the safety management system within the UKAEA which ensures that UKAEA remains the proper and effective licensee and gives some examples of how this has worked in practice. (author)

  3. Karayatak (Şabanözü güneyi) bentonitlerinin mineralojisi ve sedimantolojisi

    OpenAIRE

    DİKMEN, Asuman

    2009-01-01

    Çankırı civarında halen işletilmekte olan ve önemli rezerve sahip bentonit yatakları bulunmaktadır. Bu çalışma ile Şabanözü Karayatak Bentonit oluşumunun mineralojik ve sedimantolojik özelliklerinin incelenmesi ve kökeninin açıklanması amaçlanmıştır.İnceleme alanındaki Tersiyer istifi, Paleosen yaşlı granitoyid, Geç Miyosen yaşlı Karakocaş ve Mamak formasyonları ile Pliyosen yaşlı Bozdağ bazaltı ve Gölbaşı formasyonu olarak incelenmiştir. Şabanözü Karayatak bentonit oluşu...

  4. Süryaniler’in Tarihi ve Sosyolojik Yapısı

    OpenAIRE

    Ürek, Melki

    2014-01-01

    Bu makalede, Süryanilerin tarihi süreçleri ve sosyolojik yapıları ele alın-mıştır. Süryaniler yüzyıllar boyunca oldukça kaotik bir cooğrafyada yaşa-mışlarddır. Bu nedenle, dini, politik ve ideolojik açıdan pek çok farklı pa-radigmanın etkisi altında kalmışlardır. Bu olumsuz etki Süryanileri tarihi ve teolojik açıdan hatalı tanımlamalar ve yanlış isimlendirmeler gibi so-runlarla yüz yüze bırakmıştır. Ancak son zamanlarda üretilen akademik ve objektif çalışmalarla, Süryani liderlerin kendilerin...

  5. Sinemada uyarlama sorunsalı ve auteur bir yönetmen olarak Aki Kaurismaki

    OpenAIRE

    Mirza, Ayşe

    2016-01-01

    Bu çalışmada Aki Kaurismaki’nin Suç ve Ceza (Rikos ja rangaistus, 1983), Hamlet Goes Business (Hamlet liikemaailmassa, 1987) ve Kibritçi Kız (Tulitikkutehtaan tyttö, 1990) adlı uyarlama filmleri, auteur kuram ve minimalist üslup açısından incelenecektir. Bu bağlamda filmlerin analizlerine geçilmeden önce, uyarlama filmlerin tarihsel gelişimi ve bu konudaki tartışmalar, auteur kuram ve sinemada minimalizm konuları ele alınacak, ardından ilgili filmler betimleyici analiz yoluyla değerlendirilec...

  6. Yeni heterosiklik disazo boyarmaddelerin sentezi ve spektroskopik özelliklerinin incelenmesi

    OpenAIRE

    Demirçalı, Aykut

    2012-01-01

    Bu çalışmada, ilk etapta anilin ve anilin türevleri 3-aminokrotononitril ile kenetlenmiş daha sonra hidrazin monohidrat ve fenil hidrazin ile halka kapama reaksiyonu sonucu 5-amino-4-arilazo-3-metil-1H-pirazol (2a-2e) ve 5-amino-4-arilazo-3-metil-1-fenil-pirazol (3a-3e) türevi mono azo boyarmaddeler sentezlenmiştir. İkinci aşamada sentezlenen bu bileşikler önce diazolanmış sonrasında etil benzoil asetat ile kenetlenmiş ve yine hidrazin mono hidrat ve fenil hidrazin ile halka kapama reaksiyonu...

  7. Mineralized remains of morphotypes of filamentous cyanobacteria in carbonaceous meteorites

    Science.gov (United States)

    Hoover, Richard B.

    2005-09-01

    rocks, living, cryopreserved and fossilized extremophiles and cyanobacteria. These studies have resulted in the detection of mineralized remains of morphotypes of filamentous cyanobacteria, mats and consortia in many carbonaceous meteorites. These well-preserved and embedded microfossils are consistent with the size, morphology and ultra-microstructure of filamentous trichomic prokaryotes and degraded remains of microfibrils of cyanobacterial sheaths. EDAX elemental studies reveal that the forms in the meteorites often have highly carbonized sheaths in close association with permineralized filaments, trichomes, and microbial cells. The eextensive protocols and methodologies that have been developed to protect the samples from contamination and to distinguish recent contaminants from indigenous microfossils are described recent bio-contaminants. Ratios of critical bioelements (C:O, C:N, C:P, and C:S) reveal dramatic differences between microfossils in Earth rocks and meteorites and in the cells, filaments, trichomes, and hormogonia of recently living cyanobacteria. The results of comparative optical, ESEM and FESEM studies and EDAX elemental analyses of recent cyanobacteria (e.g. Calothrix, Oscillatoria, and Lyngbya) of similar size, morphology and microstructure to microfossils found embedded in the Murchison CM2 and the Orgueil CI1 carbonaceous meteorites are presented

  8. Remaining lifetime modeling using State-of-Health estimation

    Science.gov (United States)

    Beganovic, Nejra; Söffker, Dirk

    2017-08-01

    Technical systems and system's components undergo gradual degradation over time. Continuous degradation occurred in system is reflected in decreased system's reliability and unavoidably lead to a system failure. Therefore, continuous evaluation of State-of-Health (SoH) is inevitable to provide at least predefined lifetime of the system defined by manufacturer, or even better, to extend the lifetime given by manufacturer. However, precondition for lifetime extension is accurate estimation of SoH as well as the estimation and prediction of Remaining Useful Lifetime (RUL). For this purpose, lifetime models describing the relation between system/component degradation and consumed lifetime have to be established. In this contribution modeling and selection of suitable lifetime models from database based on current SoH conditions are discussed. Main contribution of this paper is the development of new modeling strategies capable to describe complex relations between measurable system variables, related system degradation, and RUL. Two approaches with accompanying advantages and disadvantages are introduced and compared. Both approaches are capable to model stochastic aging processes of a system by simultaneous adaption of RUL models to current SoH. The first approach requires a priori knowledge about aging processes in the system and accurate estimation of SoH. An estimation of SoH here is conditioned by tracking actual accumulated damage into the system, so that particular model parameters are defined according to a priori known assumptions about system's aging. Prediction accuracy in this case is highly dependent on accurate estimation of SoH but includes high number of degrees of freedom. The second approach in this contribution does not require a priori knowledge about system's aging as particular model parameters are defined in accordance to multi-objective optimization procedure. Prediction accuracy of this model does not highly depend on estimated SoH. This model

  9. Clarifying some remaining questions in the anomaly puzzle

    International Nuclear Information System (INIS)

    Huang, Xing; Parker, Leonard

    2011-01-01

    We discuss several points that may help to clarify some questions that remain about the anomaly puzzle in supersymmetric theories. In particular, we consider a general N=1 supersymmetric Yang-Mills theory. The anomaly puzzle concerns the question of whether there is a consistent way in the quantized theory to put the R-current and the stress tensor in a single supermultiplet called the supercurrent, even though in the classical theory they are in the same supermultiplet. It was proposed that the classically conserved supercurrent bifurcates into two supercurrents having different anomalies in the quantum regime. The most interesting result we obtain is an explicit expression for the lowest component of one of the two supercurrents in 4-dimensional spacetime, namely the supercurrent that has the energy-momentum tensor as one of its components. This expression for the lowest component is an energy-dependent linear combination of two chiral currents, which itself does not correspond to a classically conserved chiral current. The lowest component of the other supercurrent, namely, the R-current, satisfies the Adler-Bardeen theorem. The lowest component of the first supercurrent has an anomaly, which we show is consistent with the anomaly of the trace of the energy-momentum tensor. Therefore, we conclude that there is no consistent way to construct a single supercurrent multiplet that contains the R-current and the stress tensor in the straightforward way originally proposed. We also discuss and try to clarify some technical points in the derivations of the two supercurrents in the literature. These latter points concern the significance of infrared contributions to the NSVZ β-function and the role of the equations of motion in deriving the two supercurrents. (orig.)

  10. Will southern California remain a premium market for natural gas?

    International Nuclear Information System (INIS)

    John, F.E.

    1991-01-01

    Average yearly demand for natural gas in southern California totalled just over 3 billion ft 3 /d in 1991 and is projected to increase to just over 3.2 billion ft 3 /d in 2000 and 3.4 billion ft 3 /d in 2010. In the core residential market, demand is being driven by population growth and offset by conservation measures. In the core commercial and industrial market, demand is driven by employment growth and offset by conservation. In the noncore market, natural gas use is expected to fall from 262 million ft 3 /d in 1991 to 223 million ft 3 /d in 2010. Demand for natural gas for cogeneration is expected to either remain stagnant or decrease. The largest potential for market growth in southern California is for utility electric generation. Demand in this sector is expected to increase from 468 million ft 3 /d in 1991 to 1 billion ft 3 in 2010. Air quality concerns furnish a market opportunity for natural gas vehicles, and a substantial increase in natural gas demand might be obtained from even a modest market share of the region's 10 million vehicles. Existing pipeline capacity is sufficient to supply current average year requirements, and the need for new capacity hinges on the issues of satisfying high-year demand, meeting market growth, and accessing more desirable supply regions. Planned capacity additions of 2,150 million ft 3 /d, if completed, will bring substantial excess capacity to southern California in the late 1990s. The competitive advantages of various producing regions will then be greatly influenced by the rate designs used on the pipelines connecting them to the market. 4 tabs

  11. The broad spectrum revisited: evidence from plant remains.

    Science.gov (United States)

    Weiss, Ehud; Wetterstrom, Wilma; Nadel, Dani; Bar-Yosef, Ofer

    2004-06-29

    The beginning of agriculture is one of the most important developments in human history, with enormous consequences that paved the way for settled life and complex society. Much of the research on the origins of agriculture over the last 40 years has been guided by Flannery's [Flannery, K. V. (1969) in The Domestication and Exploitation of Plants and Animals, eds. Ucko, P. J. & Dimbleby, G. W. (Duckworth, London), pp. 73-100] "broad spectrum revolution" (BSR) hypothesis, which posits that the transition to farming in southwest Asia entailed a period during which foragers broadened their resource base to encompass a wide array of foods that were previously ignored in an attempt to overcome food shortages. Although these resources undoubtedly included plants, nearly all BSR hypothesis-inspired research has focused on animals because of a dearth of Upper Paleolithic archaeobotanical assemblages. Now, however, a collection of >90,000 plant remains, recently recovered from the Stone Age site Ohalo II (23,000 B.P.), Israel, offers insights into the plant foods of the late Upper Paleolithic. The staple foods of this assemblage were wild grasses, pushing back the dietary shift to grains some 10,000 years earlier than previously recognized. Besides the cereals (wild wheat and barley), small-grained grasses made up a large component of the assemblage, indicating that the BSR in the Levant was even broader than originally conceived, encompassing what would have been low-ranked plant foods. Over the next 15,000 years small-grained grasses were gradually replaced by the cereals and ultimately disappeared from the Levantine diet.

  12. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2015-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  13. Multimedia content classification metrics for content adaptation

    OpenAIRE

    Fernandes, Rui; Andrade, M.T.

    2016-01-01

    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  14. Festival du rire de Genève

    CERN Document Server

    Staff Association

    2015-01-01

    Connaissez-vous le Festival du rire de Genève ? La deuxième édition aura lieu du 25 au 28 mars 2015 au Casino-Théâtre à Carouge. Côté programmation, Marc Donnet-Monay ouvre les festivités avant trois autres soirées de folie et d’humour que nous vous laissons le soin de découvrir dans le programme : http://www.rire-geneve.ch/#programme. Réduction de 30% sur l’achat de places pour les membres du personnel du CERN. Pour cela, il suffit de se rendre sur la billetterie en ligne de notre site : www.rire-geneve.ch et d’utiliser le code promotionnel. Contacter le secrétariat de l’Association du personnel (Staff.Association@cern.ch) pour connaitre ce code promotionnel.

  15. Závodní hra ve 3D

    OpenAIRE

    Ševčík, Martin

    2010-01-01

    Táto bakalářská práce se zabývá problematikou řešení interakce Java Monkey Engine (jME) a modelů vytvořených v programu Autodesk 3D Studio Max. Obsahuje teoreticky základ k architektuře jMonkey Engine a herní knižnici Lightweight Java Game Library (LWJGL). Dále popisuje techniky při práci s objekty ve 3D scéně a jejich způsob implementace. This bachelor's thesis describes issues of interaction between Java Monkey Engine (jME) and models created with program Autodesk 3D Studio Max. It conta...

  16. Cabernet Sauvignon ve Merlot Şarapların Resveratrol Düzeyleri ve Ekolojik Koşulların Etkileri

    Directory of Open Access Journals (Sweden)

    Belkıs Çaylak Adıgüzel

    2015-02-01

    Full Text Available Fitoaleksinler bitkilerde patojen enfeksiyonuna bir reaksiyon olarak veya çeşitli biyotik ve abiyotik tetikleyicilerin etkisi sonucu oluşan fenolik madde karakterli, düşük molekül ağırlıklı antimikrobiyal bileşiklerdir. Resveratrol (trans–3,5,4’-trihidroksistilben de bir fitoaleksin olup, asma (Vitis vinifera, yer fıstığı (Arachis hypogaea ve diğer pek çok bitki türünde yaprak veya diğer organlarda yüksek miktarlarda bulunabilmektedir. Resveratrol asmada gövde, sürgün ve yapraklar yanında, özellikle renkli çeşitlerin tane kabuğunda bol miktarda sentezlenebilmekte ve şarap yapımı sırasında şıraya, şıradan da şaraba geçmektedir. Son yıllarda resveratrolün antikanserojen özelliği ve antioksidan karakteri nedeniyle sağlık yararları üzerine yoğun araştırmalar yapılmakta ve günlük diyette alımı önerilmektedir. Bu çalışmada, Ege, Marmara ve Trakya Bölgeleri’nde üretilen kimi bağlardan sağlanan Cabernet sauvignon ve Merlot siyah üzümlerinden üretilmiş şaraplarda bulunan resveratrol miktarları Yüksek Performanslı Sıvı Kromatografisi yöntemi kullanılarak belirlenmiştir. Elde edilen sonuçlar bölgelerin ekolojik koşulları açısından birbirleriyle karşılaştırılmış ve resveratrol miktarı ile bu parametreler arasındaki korelasyon araştırılmıştır. Resveratrol konsantrasyonunun üzüm çeşidi ve bölgelerin iklim şartlarına bağlı olarak farklılıklar gösterebileceği görülmüştür.

  17. Bitkisel Ürünlerin ve Gıda Destek Ürünlerinin İçeriklerinin Adli ve Hukuki Boyutu

    Directory of Open Access Journals (Sweden)

    Zeynep Türkmen

    2014-09-01

    Full Text Available Günümüzde alternatif ya da destekleyici tedavi yöntemlerine ve bunlara bağlı olarak bitkisel ürünlere artan bir ilgi söz konusudur. Bu ürünler Gıda, Tarım ve Hayvancılık Bakanlığı’ndan gıda destek maddesi ruhsatı alınarak, “gıda takviyesi” adı altında piyasaya sürülmektedir. Bu tip ürünler ilaç statüsünde olmadığından ruhsatlandırılması ve piyasaya arzı farklılık gösterebilmektedir. Bu ürünlerle ilgili sıklıkla gözlenen sorunlar arasında kontaminasyon, katkı maddeleri, toksisite ve yanlış doz ve etiketlemeden kaynaklı tek tip üretim problemleri sayılabilir. Son zamanlarda söz konusu ürünlere ait zehirlenmeler ve ilaç etkileşimlerinin neden olduğu istenmeyen ve beklenmeyen durumlar gözlemlenmektedir. Bu gözlemler, alternatif ya da destekleyici ürün adı altında piyasaya sunulan bitkisel ürünlerin üretimi, ruhsatlandırılması, satışı ve denetimi konusunda ciddi düzenlemelere ve uygulamalara ihtiyaç olduğunu göstermektedir. Çalışmamızın amacı, laboratuarımıza içerik analizi için yönlendirilen, ikisi bakanlık onayı olmaksızın bitkisel ürün adı altında satılmakta olan, diğeri ise bakanlık onaylı sporcu destek ürünü olmak üzere üç olgudan elde edilen bulgularımızı sunmak ve ilgili olguları Türk Ceza Kanunun hükümlerine göre değerlendirmektir. Anahtar kelimeler: Bitkisel ürünler, Sibutramine, sporda kullanılan destek ürünleri, Cinnarizine, GC-MS.

  18. The Right to Remain Silent in Criminal Trial

    Directory of Open Access Journals (Sweden)

    Gianina Anemona Radu

    2013-05-01

    Full Text Available A person's right not to incriminate oneself or to remain silent and not contribute to their own incrimination is a basic requirement of due process, although the right not to testify against oneself is not expressly guaranteed. This legal right is intended to protect the accused/ the defendant against the authorities’ abusive coercion. The scope of the right not to incriminate oneself is related to criminal matter under the Convention, and thus susceptible or applicable to criminal proceedings concerning all types of crimes as a guarantee to a fair trial. The European Court of Justice ruled that despite the fact that art. 6 paragraph 2 of the Convention does not expressly mention the right not to incriminate oneself and the right not to contribute to their own incrimination (nemo tenetur are ipsum accusare these are generally recognized international rules that are in consistence with the notion of “fair trial” stipulated in art. 6. By virtue of the right to silence, the person charged with a crime is free to answer the questions or not, as he/she believes it is in his/her interest. Therefore, the right to silence involves not only the right not to testify against oneself, but also the right of the accused/ defendant not to incriminate oneself. Thus, the accused/defendant cannot be compelled to assist in the production of evidence and cannot be sanctioned for failing to provide certain documents or other evidence. Obligation to testify against personal will, under the constraint of a fine or any other form of coercion constitutes an interference with the negative aspect of the right to freedom of expression which must be necessary in a democratic society. It is essential to clarify certain issues as far as this right is concerned. First of all, the statutory provision in question is specific to adversarial systems, which are found mainly in Anglo-Saxon countries and are totally different from that underlying the current Romanian Criminal

  19. AIDS, individual behaviour and the unexplained remaining variation.

    Science.gov (United States)

    Katz, Alison

    2002-01-01

    From the start of the AIDS pandemic, individual behaviour has been put forward, implicitly or explicitly, as the main explanatory concept for understanding the epidemiology of HIV infection and in particular for the rapid spread and high prevalence in sub-Saharan Africa. This has had enormous implications for the international response to AIDS and has heavily influenced public health policy and strategy and the design of prevention and care interventions at national, community and individual level. It is argued that individual behaviour alone cannot possibly account for the enormous variation in HIV prevalence between population groups, countries and regions and that the unexplained remaining variation has been neglected by the international AIDS community. Biological vulnerability to HIV due to seriously deficient immune systems has been ignored as a determinant of the high levels of infection in certain populations. This is in sharp contrast to well proven public health approaches to other infectious diseases. In particular, it is argued that poor nutrition and co-infection with the myriad of other diseases of poverty including tuberculosis, malaria, leishmaniasis and parasitic infections, have been neglected as root causes of susceptibility, infectiousness and high rates of transmission of HIV at the level of populations. Vulnerability in terms of non-biological factors such as labour migration, prostitution, exchange of sex for survival, population movements due to war and violence, has received some attention but the solutions proposed to these problems are also inappropriately focused on individual behaviour and suffer from the same neglect of economic and political root causes. As the foundation for the international community's response to the AIDS pandemic, explanations of HIV/AIDS epidemiology in terms of individual behaviour are not only grossly inadequate, they are highly stigmatising and may in some cases, be racist. They have diverted attention from

  20. 76 FR 24883 - DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global...

    Science.gov (United States)

    2011-05-03

    ... FEDERAL MARITIME COMMISSION [Docket No. 11-07] DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global Lojistiks Ve Gumruk Musavirligi A.S., Barsan International... AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. (``AFI''), hereinafter ``Complainants...

  1. Big Bang à Genève - French version only

    CERN Multimedia

    2005-01-01

    C'est la dernière conférence du cycle organisé par la section de physique de l'Université de Genève à l'occasion de l'Année internationale de la physique. Pour le bouquet final, la section de physique a choisi le grand boum du Big Bang. Intitulée « Big Bang à Genève », la conférence donnée par Laurent Chevalier de l'institut français CEA Saclay évoquera les expériences qui se préparent au CERN avec le LHC. Leur but est de reproduire et d'analyser les conditions qui prévalaient à l'origine de l'Univers, juste après le Big Bang. L'exposé décrira de façon simple les techniques utilisées pour cette exploration, qui démarrera en 2007. Laurent Chevalier se demandera avec le public quels phénomènes nouveaux les physiciens espèrent découvrir dans ce monde inexploré. Comme les précédentes, la conférence débutera par une démonstration de détection de rayons cosmiques dans l'auditoire et l'utilisation de ces signaux pour créer une « musique cosmique », en collaboration avec le Pr...

  2. Cordia Sebestena Tohumunun ve Tohum Yağının Besinsel Özellikleri ve Potansiyel Değeri (İngilizce

    Directory of Open Access Journals (Sweden)

    Foluso O. Agunbiade

    2015-02-01

    Full Text Available Az kullanılan hammaddelerin geliştirilmesinin ivme kazanması ile iyi bilinen tohum ve tohum yağlarına olan aşırı bağımlılıktan ve bunun sonucundaki yüksek maliyetten dolayı geleneksel ve endüstriyel uygulamalar için az bilinen tohum ve tohum yağları türetilmiştir. Bu nedenle Cordia sebestena tohum ve tohum yağının kullanım potansiyeli bakımından besinsel özelliklerinin değerlendirilmesine yönelik bu çalışma yapılmıştır. Tohum yağında literatürde rapor edilen çeşitli analizler kullanılarak yağ asidi profili incelenmiş ve karakterize edilmişken, tohumda ise genel bileşim, mineral bileşenler ve anti-besinsel faktörler araştırılmıştır. Sonuçlar tohumun iyi bir yağ (%40.3 ± 0.8 ve protein (%11.5 ± 0.6 kaynağı olabileceğini göstermektedir. Tohum aynı zamanda Mg, Ca ve Na benzeri bazı makro-elementler ile esansiyel bir mikro-element olan Zn kaynağı olabilir. Anti-besinlerden fitat, tanen ve oksalat içeriği yüksektir ve gıdalarda tohumun kullanımı sakıncalı olabilir. Bu maddeler belki geleneksel gıda işleme yöntemleri ile giderilebilir. Tohum yağının özellikleri onun alkid reçine sentezinde, biyodizel ve sabun üretiminde kullanışlı olabileceğini göstermektedir. Yağ asidi profili toplam yağın %71.1 oranında insan tüketimi için iyi bir yağ asidi olan oleik asiti (C18:1 ağırlıklı olarak bulundurduğunu göstermektedir. Cordia sebestena tohumu ve tohum yağının önemli kullanım alanları olabileceği görülmüştür, ancak tohum yağının aminoasit profili ve anti-besinler üzerine geleneksel işlemlerin etkileri konularında daha fazla çalışmaya ihtiyaç vardır.

  3. Samuel Lysons and His Circle: Art, Science and the Remains of Roman Britain

    Directory of Open Access Journals (Sweden)

    Sarah Ann Scott

    2013-09-01

    Full Text Available This paper critically evaluates the social and intellectual influences which shaped Samuel Lysons’ (1763–1819 interests in the archaeological remains of Roman Britain, and assesses the extent to which his work was innovative. While Romano-British archaeologists have long admired his achievements, there has been no detailed examination of the factors influencing the development of his interests and approach. This paper will outline how Lysons’ social networks, his genuine concern for preserving and recording Romano-British remains, his broad scholarly interests, and the support of an intellectual elite involved with the expansion of national institutions during a period characterized by intense international rivalry, resulted in his exemplary approach to the excavation and publication of the remains of Roman Britain. Scrutiny of newspaper reports, diaries, correspondence, and the previously unpublished contents of his personal library, and an examination of his publications in relation to contemporary Classical and scientific scholarship, shows how and why his work was at the forefront of archaeological scholarship in this period. The results of this study support his reputation as a founding father of Romano-British archaeology and show that both he and his associates deserve far wider recognition of their contributions to the development of archaeology as a whole.

  4. Biyodizel ve Karışımlarının Kullanıldığı bir Dizel Motorda Performans ve Emisyon Analizi

    Directory of Open Access Journals (Sweden)

    Ahmet Necati ÖZSEZEN

    2009-02-01

    Full Text Available Bu çalışmada, atık palmiye yağı kökenli biyodizel ve petrol kökenli dizel yakıtı (PKDY ile karışımlarının, bir dizel motordaki performans ve emisyon karakteristikleri üç boyutlu haritalar üzerinden analiz edilmiştir. Biyodizel ve karışımlarının performans ve emisyon karakterlerini belirlemek amacıyla, motor tam yük ve değişik devir testlerine tabi tutulmuştur. Analiz sonucunda, karışımdaki biyodizel oranı arttıkça PKDY'a göre özgül yakıt tüketiminde artış olduğu, motorun döndürme momentinde ise azalma meydana geldiği tespit edilmiştir. Emisyon analizi sonucunda ise, karışımdaki biyodizel oranı ile ilişkili olarak PKDY'a kıyasla yanmamış hidrokarbon (HC, karbon monoksit (CO ve duman koyuluğu emisyonlarında iyileşmeler olduğu, bununla birlikte karbon dioksit (CO2 ve azot oksit (NOx emisyonlarının motor devrine göre kararlı bir yapı sergilemediği belirlenmiştir.

  5. NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm

    Directory of Open Access Journals (Sweden)

    Jin Changjiang

    2006-10-01

    Full Text Available Abstract Background Protein palmitoylation, an essential and reversible post-translational modification (PTM, has been implicated in cellular dynamics and plasticity. Although numerous experimental studies have been performed to explore the molecular mechanisms underlying palmitoylation processes, the intrinsic feature of substrate specificity has remained elusive. Thus, computational approaches for palmitoylation prediction are much desirable for further experimental design. Results In this work, we present NBA-Palm, a novel computational method based on Naïve Bayes algorithm for prediction of palmitoylation site. The training data is curated from scientific literature (PubMed and includes 245 palmitoylated sites from 105 distinct proteins after redundancy elimination. The proper window length for a potential palmitoylated peptide is optimized as six. To evaluate the prediction performance of NBA-Palm, 3-fold cross-validation, 8-fold cross-validation and Jack-Knife validation have been carried out. Prediction accuracies reach 85.79% for 3-fold cross-validation, 86.72% for 8-fold cross-validation and 86.74% for Jack-Knife validation. Two more algorithms, RBF network and support vector machine (SVM, also have been employed and compared with NBA-Palm. Conclusion Taken together, our analyses demonstrate that NBA-Palm is a useful computational program that provides insights for further experimentation. The accuracy of NBA-Palm is comparable with our previously described tool CSS-Palm. The NBA-Palm is freely accessible from: http://www.bioinfo.tsinghua.edu.cn/NBA-Palm.

  6. NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm.

    Science.gov (United States)

    Xue, Yu; Chen, Hu; Jin, Changjiang; Sun, Zhirong; Yao, Xuebiao

    2006-10-17

    Protein palmitoylation, an essential and reversible post-translational modification (PTM), has been implicated in cellular dynamics and plasticity. Although numerous experimental studies have been performed to explore the molecular mechanisms underlying palmitoylation processes, the intrinsic feature of substrate specificity has remained elusive. Thus, computational approaches for palmitoylation prediction are much desirable for further experimental design. In this work, we present NBA-Palm, a novel computational method based on Naïve Bayes algorithm for prediction of palmitoylation site. The training data is curated from scientific literature (PubMed) and includes 245 palmitoylated sites from 105 distinct proteins after redundancy elimination. The proper window length for a potential palmitoylated peptide is optimized as six. To evaluate the prediction performance of NBA-Palm, 3-fold cross-validation, 8-fold cross-validation and Jack-Knife validation have been carried out. Prediction accuracies reach 85.79% for 3-fold cross-validation, 86.72% for 8-fold cross-validation and 86.74% for Jack-Knife validation. Two more algorithms, RBF network and support vector machine (SVM), also have been employed and compared with NBA-Palm. Taken together, our analyses demonstrate that NBA-Palm is a useful computational program that provides insights for further experimentation. The accuracy of NBA-Palm is comparable with our previously described tool CSS-Palm. The NBA-Palm is freely accessible from: http://www.bioinfo.tsinghua.edu.cn/NBA-Palm.

  7. CERN hosts Tour du canton de Genève stage

    CERN Multimedia

    2004-01-01

    CERN's John Osborne (TS) at the start of the 10 km with more than 1700 other runners. Good luck to the CERN runners in the forthcoming stages! CERN hosted the first stage of the 10th Tour du canton de Genève on the evening of Wednesday 26 May. The Tour du canton is an annual race run in four stages over four weeks, and this year started at CERN as part of the Golden Jubilee celebrations. The event attracted over 2000 runners, including over 40 from CERN, as well as a large crowd of onlookers. The 10.5 km route started and finished outside CERN's Main Building, taking in the Swiss countryside, crossing into France and coming back through the tunnel linking the two CERN sites. CERN runners finished in second place in the Enterprise category just 13 seconds behind Rolex S.A., setting up an exciting contest for the remaining stages at Bernex, Meyrin and Jussy.Results are on the Tour du canton website.

  8. VERGİ GELİRLERİ VE KAMU HARCAMALARI AÇISINDAN ENFLASYON: TANZİ VE TERS TANZİ ETKİLERİ

    OpenAIRE

    ÇAVUŞOĞLU, A. Tarkan

    2005-01-01

    Bu çalışma, Tanzi etkisi olarak adlandırılan enflasyonun reel vergi gelirleri üzerindeki etkisi ile ters Tanzi etkisi olarak adlandırılan enflasyonun reel kamu harcamaları üzerindeki etkisini konu etmektedir. Çalışmada, enflasyonun bütçe dengesi üzerindeki etkisi, Tanzi ve ters Tanzi etkileri kapsamında ekonometrik bir yaklaşımla incelenmeye çalışılmıştır. Elde edilen ampirik bulgular, 1987-2003 döneminde Türkiye ekonomisinde yaşanan yüksek enflasyonun, hem vergi gelirlerinin hem de kamu har...

  9. Atatürk ve Güzel Sanatlar

    Directory of Open Access Journals (Sweden)

    Nurgün Koç

    2012-07-01

    Full Text Available Özet Bilindiği üzere Türkiye Cumhuriyeti’nin kurulmasından kısa süre sonra hemen hemen her alanı kapsayan bir reform süreci başlatılmıştır. Bu yenilik hareketleri sosyal, siyasal, ekonomik vb. alanlarda görüldüğü gibi kültürel konularda da karşımıza çıkmaktadır. Atatürk kültürün önemli unsurlarından biri olan güzel sanatlardaki gelişime çok önem vermiş ve teşvik etmiştir. Uygar ülkeler arasına girmenin güzel sanatlar alanındaki başarılara bağlı olduğunu belirtmiştir. Bu yüzden 1936 yılında Devlet Konservatuarı kurulmuş, sahne sanatları, resim, müzik, heykel v.b güzel sanatların her alanında sanatçıların yetişmesi sağlanmıştır. Bu arada geleneksel sanatlara da önem verilmiş fakat Batılılaşma sürecinin hızıyla biraz geri planda kalmışlardır. Ataturk and Fine Arts Abstract As known, soon after Turkish Republic was founded, a reform process covering almost all fields was launched. These reform movements are also seen in cultural issues as well as in social, political and economic fields. Ataturk attached great importance to the development in fine arts which is one of the important elements of the culture and encouraged it. He stated that entering into civilized countries is up to the achievements in the field of fine arts. Therefore, state conservatory was founded in 1936 and artists in all fields of fine arts like performing arts, painting, music, sculpture were raised. Meanwhile, traditional arts were also emphasized, but remained a bit in the background because of fast process of Westernization. Atatürk et Les Beaux-Arts Résumé Comme on le sait, peu de temps après la fondation de la République de Turquie, le processus de réforme a été lancé dans presque tous les domaines. Ces mouvements d’innovation apparaissent dans les domaines culturels ainsi que dans les domaines sociaux, politiques et économiques. Atatürk a aussi accordé une grande importance au d

  10. Atatürk ve Güzel Sanatlar

    Directory of Open Access Journals (Sweden)

    Nurgün Koç

    2012-06-01

    Full Text Available ÖzetBilindiği üzere Türkiye Cumhuriyeti’nin kurulmasından kısa süre sonra hemen hemen her alanı kapsayan bir reform süreci başlatılmıştır. Bu yenilik hareketleri sosyal, siyasal, ekonomik vb. alanlarda görüldüğü gibi kültürel konularda da karşımıza çıkmaktadır. Atatürk kültürün önemli unsurlarından biri olan güzel sanatlardaki gelişime çok önem vermiş ve teşvik etmiştir. Uygar ülkeler arasına girmenin güzel sanatlar alanındaki başarılara bağlı olduğunu belirtmiştir. Bu yüzden 1936 yılında Devlet Konservatuarı kurulmuş, sahne sanatları, resim, müzik, heykel v.b güzel sanatların her alanında sanatçıların yetişmesi sağlanmıştır. Bu arada geleneksel sanatlara da önem verilmiş fakat Batılılaşma sürecinin hızıyla biraz geri planda kalmışlardır.Abstract As known, soon after Turkish Republic was founded, a reform process covering almost all fields was launched. These reform movements are also seen in cultural issues as well as in social, political and economic fields. Ataturk attached great importance to the development in fine arts which is one of the important elements of the culture and encouraged it. He stated that entering into civilized countries is up to the achievements in the field of fine arts. Therefore, state conservatory was founded in 1936 and artists in all fields of fine arts like performing arts, painting, music, sculpture were raised. Meanwhile, traditional arts were also emphasized, but remained a bit in the background because of fast process of Westernization. RésuméComme on le sait, peu de temps après la fondation de la République de Turquie, le processus de réforme a été lancé dans presque tous les domaines. Ces mouvements d’innovation apparaissent dans les domaines culturels ainsi que dans les domaines sociaux, politiques et économiques. Atatürk a aussi accordé une grande importance au développement des beaux-arts qui sont un des

  11. VeA of Aspergillus niger increases spore dispersing capacity by impacting conidiophore architecture.

    Science.gov (United States)

    Wang, Fengfeng; Dijksterhuis, Jan; Wyatt, Timon; Wösten, Han A B; Bleichrodt, Robert-Jan

    2015-01-01

    Aspergillus species are highly abundant fungi worldwide. Their conidia are among the most dominant fungal spores in the air. Conidia are formed in chains on the vesicle of the asexual reproductive structure called the conidiophore. Here, it is shown that the velvet protein VeA of Aspergillus niger maximizes the diameter of the vesicle and the spore chain length. The length and width of the conidiophore stalk and vesicle were reduced nearly twofold in a ΔveA strain. The latter implies a fourfold reduced surface area to develop chains of spores. Over and above this, the conidial chain length was approximately fivefold reduced. The calculated 20-fold reduction in formation of conidia by ΔveA fits the 8- to 17-fold decrease in counted spore numbers. Notably, morphology of the ΔveA conidiophores of A. niger was very similar to that of wild-type Aspergillus sydowii. This suggests that VeA is key in conidiophore architecture diversity in the fungal kingdom. The finding that biomass formation of the A. niger ΔveA strain was reduced twofold shows that VeA not only impacts dispersion capacity but also colonization capacity of A. niger.

  12. Most B cells in non-lymphoid tissues are naïve.

    Science.gov (United States)

    Inman, Charlotte F; Murray, Tamsin Zangerle; Bailey, Mick; Cose, Stephen

    2012-02-01

    The current view of lymphocyte migration states that naïve lymphocytes re-circulate between the blood and the lymph via the lymph nodes, but are not able to access non-lymphoid tissues. We examined B lymphocytes in peripheral tissues and found that the majority were phenotypically similar to naïve B cells in lymphoid tissues and were located within the parenchyma, not associated with blood vessels. The mutation rate within the Vh region of these cells was substantially less than the rate attributed to somatic hypermutation and was identical to that observed in naïve B cells isolated from the lymph nodes, showing the presence of naïve B cells in the non-lymphoid organs. Further, using FTY720-treated mice, we showed that naïve B cells migrate through the peripheral tissues and, using pertussis toxin, that the entry of B cells was not controlled by chemokine-mediated signalling events. Overall, these results show that naïve B lymphocytes constitute the majority of the total B-cell population in non-lymphoid tissues and suggest that these cells may re-circulate through the periphery as part of their normal migration pathway. This has implications for the current view of the role of naïve B cells in priming and tolerance.

  13. Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

    Directory of Open Access Journals (Sweden)

    Kunihiko Hatanaka

    Full Text Available The fibroblast growth factor (FGF system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood. In the present study, we aimed to investigate the detailed mechanism of FGF regulation of VE-cadherin function that leads to endothelial junction stabilization.In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin. Among protein tyrosine phosphatases (PTPs known to be involved in the maintenance of the VE-cadherin complex, suppression of FGF signaling reduces SHP2 expression levels and SHP2/VE-cadherin interaction due to accelerated SHP2 protein degradation. Increased endothelial permeability caused by FGF signaling inhibition was rescued by SHP2 overexpression, indicating the critical role of SHP2 in the maintenance of endothelial junction integrity.These results identify FGF-dependent maintenance of SHP2 as an important new mechanism controlling the extent of VE-cadherin tyrosine phosphorylation, thereby regulating its presence in adherens junctions and endothelial permeability.

  14. Tulum Peynirlerinden izole Edilen Lactococcus lactis subsp. lactis YBML9 ve

    Directory of Open Access Journals (Sweden)

    Yasin TUNCER

    2009-04-01

    Full Text Available Bu çalısmanın amacı tulum peynirlerinden izole edilen Lactococcus lactis suslarının fenotipik tanısı ve bu suslar tarafından üretilen bakteriyosinlerin kısmi karakterizasyonlarıdır. Bu amaçla Türkiye'nin sekiz farklı ilinden (Ankara, Antalya, Burdur, Denizli, Erzincan, Isparta, İstanbul ve İzmir yöresel pazarlardan toplanan 60 adet tulum peyniri örneginden 40 adet Lactococcus lactis susu (31 adet L. lactis subsp. lactis ve 9 adet L. lactis subsp. cremoris izole edildi. 40 adet L. lactis susu içerisinden, 2 adet L. lactis subsp. lactis (YBML9 ve YBML21 susu bakteriyosin üretme yeteneginde bulundu. L. lactis subsp. lactis YBML9 ve YBML21 susları tarafından üretilen bakteriyosinler, farklı enzim, pH ve sıcaklık uygulamaları sonucu; sırasıyla nisin ve laktisin 481 olarak tanımlandı.

  15. 76 FR 14057 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... Anthropology Department, Human Remains Repository, Laramie, WY. The human remains and associated funerary... the human remains was made by University of Wyoming, Anthropology Department, Human Remains Repository...

  16. Distinct IL-7 signaling in recent thymic emigrants versus mature naïve T cells controls T-cell homeostasis.

    Science.gov (United States)

    Kim, Hye Kyung; Waickman, Adam T; Castro, Ehydel; Flomerfelt, Francis A; Hawk, Nga V; Kapoor, Veena; Telford, William G; Gress, Ronald E

    2016-07-01

    IL-7 is essential for T-cell survival but its availability is limited in vivo. Consequently, all peripheral T cells, including recent thymic emigrants (RTEs) are constantly competing for IL-7 to survive. RTEs are required to replenish TCR diversity and rejuvenate the peripheral T-cell pool. However, it remains unknown how RTEs successfully compete with resident mature T cells for IL-7. Moreover, RTEs express low levels of IL-7 receptors, presumably rendering them even less competitive. Here, we show that, surprisingly, RTEs are more responsive to IL-7 than mature naïve T cells as demonstrated by markedly increased STAT5 phosphorylation upon IL-7 stimulation. Nonetheless, adoptive transfer of RTE cells into lymphopenic host mice resulted in slower IL-7-induced homeostatic proliferation and diminished expansion compared to naïve donor T cells. Mechanistically, we found that IL-7 signaling in RTEs preferentially upregulated expression of Bcl-2, which is anti-apoptotic but also anti-proliferative. In contrast, naïve T cells showed diminished Bcl-2 induction but greater proliferative response to IL-7. Collectively, these data indicate that IL-7 responsiveness in RTE is designed to maximize survival at the expense of reduced proliferation, consistent with RTE serving as a subpopulation of T cells rich in diversity but not in frequency. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  17. Bazı Şekerlemeler ve Yapay Toz İçeceklerdeki Diazo Boyar Madde Olan Sunset Yellow FCF ile Tartrazin Miktar Tayinlerinin Voltametrik ve Spektrofotometrik Metod Karşılaştırması

    Directory of Open Access Journals (Sweden)

    Nejat Altıniğne

    2015-02-01

    Full Text Available Bazı şekerlemeler ve toz içeceklere katımlı olan sunset yellow FCF ve tartrazin boyar maddelerin analizleri, voltametrik (DPP ve spektrofotometrik metotlarla yapılarak karşılaştırılmıştır. Şekerlemelerde ve sentetik toz içeceklerde boyar maddenin yalnız bir tanesi bulunduğunda, doğru, hassas ve güvenli sonuçlar elde edilebilmektedir. Uygulanan her iki metodun korelasyon sayısı r= 0.995 ve tayin sınıfları 0.8 mg/ml olarak saptanmıştır. Bu çalışma nitel ve nicel tayinlerin, spektrofotometrik metot yanında voltametri metoduyla da yapılabildiğini göstermiştir.

  18. Psoriasisin Sistemik Tedavi Kilavuzu: Yöntem Seçimi ve Izlemle Ilgili Pratik Öneriler, Tartismali Konular

    Directory of Open Access Journals (Sweden)

    Tülin Ergun

    2007-03-01

    Full Text Available Psoriasis, sik görülen, çogu kez yasam boyunca süren ve genellikle tedaviyle yok edilemeyen bir hastaliktir. Bu durum, hastalarin yasam boyunca tedavi edilmesini ve özellikle siddetli hastaligi olan hastalarda, önemli yan etkileri olan ilaçlarin uzun süreli kullanilmasini gerektirir. Bu derlemenin amaci, dermatoji uzmanina, orta ve siddetli psoriasisi olan bir hastayla karsilastiginda hangi yöntemi seçmesi gerektigiyle ilgili rehberlik edebilmektir. Bu baglamda fototerapi, geleneksel ve biyolojik tedavi ajanlari, avantaj ve dezavantajlari, izlemde dikkat edilmesi gereken yönleriyle tartisilacaktir.

  19. Water content of aged aerosol

    OpenAIRE

    G. J. Engelhart; L. Hildebrandt; E. Kostenidou; N. Mihalopoulos; N. M. Donahue; S. N. Pandis

    2010-01-01

    The composition and physical properties of aged atmospheric aerosol were characterized at a remote sampling site on the northern coast of Crete, Greece during the Finokalia Aerosol Measurement Experiment in May 2008 (FAME-2008). A reduced Dry-Ambient Aerosol Size Spectrometer (DAASS) was deployed to measure the aerosol water content and volumetric growth factor of fine particulate matter. The particles remained wet even at relative humidity (RH) as low as 20%. The aerosol was acidic during mo...

  20. Prehransko opismenjevanje otrok z vidika usvajanja prehranskih veščin

    OpenAIRE

    Kostanjevec, Stojan; Erjavšek, Martina

    2017-01-01

    Na zdravje in kakovost življenja posameznika vpliva stopnja njegove prehranske pismenosti, katere pomemben del so tudi usvojene prehranske veščine in od katerih je odvisen izbor hrane, ki jo posameznik pripravlja in uživa. Prehransko vešč posameznik je zmožen uporabiti usvojeno prehransko znanje pri načrtovanju prehrane, nakupovanju živil in pri pripravi obrokov hrane. Namen raziskave je bil ugotoviti, katere prehranske veščine usvojijo osnovnošolci v šolskem in domačem okolju ter kako pogost...

  1. Melatonin ve Bağışıklık Sistemi

    OpenAIRE

    ÇETİN, E.

    2005-01-01

    Melatonin, pineal bezin beta adrenerjik reseptörlerinin aktivasyonu ile triptofandan sentezlenen bir hormondur.Üretim ve salınımı karanlık ile başlar ve aydınlıkla sona erer. Melatonin, birçok biyolojik fonksiyonun düzenlenmesinderol oynar. Bu derlemede melatonin hakkında genel bilgiler verilerek, melatoninin lenfoid dokular, humoral bağışıklık,hücresel bağışıklık ve kanser üzerine etkileri tartışılmıştır

  2. Salicornia, Sarcocornia ve Arthrocnemum cinslerinin (Chenopodiaceae) Türkiye taksonomik revizyonu

    OpenAIRE

    YAPRAK, Ahmet Emre

    2008-01-01

    Bu çalışmada Türkiye’de bulunan Salicornia L., Sarcocornia A. J. Scott ve Arthrocnemum Moq. cinslerine ait türlerin morfolojik, karyolojik, biyocoğrafik özelliklerinin ve filogenetik ilişkilerinin tanımlanması amaçlanmıştır. Araştırmalar sonucunda Türkiye Florasında verilen Salicornia fragilis P. W. Ball & Tutin, Salicornia europaea L. ve Sarcocornia fruticosa &l...

  3. Rizâeddin b. Fahreddin ve Kütüb-i Sitte ve Müellifleri adlı eseri

    OpenAIRE

    KHAZİEV, Rinat

    2015-01-01

    Tez bir Girişten ve üç bölümden oluşmaktadır. Girişte tezin içerdiği bilgiler ve hazırlanmasında izlenen yöntem hakkında bilgiler verilmiştir.Tezin birinci bölümünde Rizâeddin b. Fahreddin’in hayatına dair bilgiler sunulmuştur. Onun şahsiyeti, âlimliği, başmuharrirliği ve sosyal faaliyetleri gösterilmiştir. Diğer taraftan da onun hayatı, ilmi tahsili, hocaları ve eserleri ele alınmıştır.Araştırmanın ikinci bölümde Rizâeddin b. Fahreddin’n Hadis ilmine bakışı ve yaklaşımı tahlil edilm...

  4. Walk This Way: Detailed Steps for Transferring Born-Digital Content from Media You Can Read In-House

    Science.gov (United States)

    Barrera-Gomez, Julianna; Erway, Ricky

    2013-01-01

    This document is a companion to the report, "You've Got to Walk before You Can Run: First Steps for Managing Born-Digital Content Received on Physical Media." Like the "First Steps" report, the intended audience is those who are just starting to manage born-digital materials, from those wondering where to begin, to those who…

  5. THE PERCEPTION OF OLD AND NEW VALUES IN THE TWO STORIES OF ÖMER SEYFETTİN “BAHAR VE KELEBEKLER” AND “AŞK DALGASI” ÖMER SEYFETTİN’İN “BAHAR VE KELEBEKLER” İLE “AŞK DALGASI” ADLI İKİ HİKÂYESİNDE ESKİ VE YENİ DEĞERLER ALGISI

    Directory of Open Access Journals (Sweden)

    Gülten BULDUKER

    2012-01-01

    Full Text Available Ömer Seyfettin, a Pioneer within them ovement of Genç Kalemler, is a distinguished writer with his essay sand stories. He has aimed to write his work swith a pure language and national in an emotional way. The attitude, the post Tanzimat philosophers had taken, with the ideas towards the value judgements, more or less have defined the contents of his works. The writer is in search of new values to shape the society. In this article it has been the main goal toindicate Ömer Seyfettin’s ideas about the old and the modern way of life, and some sort of dilemmas he has been through in Bahar ve Kelebekler and Aşk Dalgası. It is seen that the writer, who believes that maro cilised society can be provided only by breaking hard fanaticism, supports equality of men and women, criticises arranged marriage style, is dreaming of a progressand development Ömer Seyfettin, öncüsü olduğu Genç Kalemler hareketi içerisinde hikâye ve makaleleriyle öne çıkan bir yazardır. Eserlerini sade bir dil ve millî bir duyuş-düşünüşle kaleme almayı amaçlamıştır. Tanzimat sonrası fikir adamlarının “Doğu ve Batı”ya ait değer yargıları karşısındaki düşünceleri ile almış oldukları tavır, az çok onun eserlerinin de muhtevasını belirlemiştir. Yazar, eski gelenek ve göreneklerin önemini yitirmesi durumunda, topluma şekil verecek yeni değerlerin arayışı içerisindedir. Bu makalede Ömer Seyfettin’in Bahar ve Kelebekler ile Aşk Dalgası adlı hikâyelerinde eski ve yeni yaşam tarzı konusundaki düşünceleri ile düştüğü bazı çelişkili durumlar sergilenmeye çalışılmıştır. Daha medenî bir toplum yapısının katı taassupların kırılmasıyla sağlanabileceğine inanan yazarın, kadın-erkek eşitliğini savunduğu, görücü usulünü eleştirdiği; ilim ve fen ışığında bir yükselme, ilerleme hayal ettiği görülmektedir.

  6. Introduction: From pathogenesis to therapy, deep endometriosis remains a source of controversy.

    Science.gov (United States)

    Donnez, Jacques

    2017-12-01

    Deep endometriosis remains a source of controversy. A number of theories may explain its pathogenesis and many arguments support the hypothesis that genetic or epigenetic changes are a prerequisite for development of lesions into deep endometriosis. Deep endometriosis is frequently responsible for pelvic pain, dysmenorrhea, and/or deep dyspareunia, but can also cause obstetrical complications. Diagnosis may be improved by high-quality imaging. Therapeutic approaches are a source of contention as well. In this issue's Views and Reviews, medical and surgical strategies are discussed, and it is emphasized that treatment should be designed according to a patient's symptoms and individual needs. It is also vital that referral centers have the knowledge and experience to treat deep endometriosis medically and/or surgically. The debate must continue because emerging trends in therapy need to be followed and investigated for optimal management. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  7. Cabernet Sauvignon ve Merlot Şarapların Resveratrol Düzeyleri ve Ekolojik Koşulların Etkileri

    OpenAIRE

    Belkıs Çaylak Adıgüzel; Nedim Çetinkaya; Ufuk Yücel

    2015-01-01

    Fitoaleksinler bitkilerde patojen enfeksiyonuna bir reaksiyon olarak veya çeşitli biyotik ve abiyotik tetikleyicilerin etkisi sonucu oluşan fenolik madde karakterli, düşük molekül ağırlıklı antimikrobiyal bileşiklerdir. Resveratrol (trans–3,5,4’-trihidroksistilben) de bir fitoaleksin olup, asma (Vitis vinifera), yer fıstığı (Arachis hypogaea) ve diğer pek çok bitki türünde yaprak veya diğer organlarda yüksek miktarlarda bulunabilmektedir. Resveratrol asmada gövde, sürgün ve yapraklar yanında,...

  8. Pre-emptif uygulanan intravenöz, spinal ve epidural morfinin erken postoperatif analjezi ve stres yanıt üzerine etkileri

    OpenAIRE

    Düger, Cevdet; Ayvaz, Hakan; Bulut, Filiz; Gürsoy, Sinan; Kaygusuz, Kenan; İsbir, Ahmet Cemil; Özdemir Kol, İclal; Gürelik, Bilge; Mimaroğlu, Caner

    2013-01-01

    Özet Bu çalışmada, preemptif uygulanan iv, spinal ve epidural morfinin erken postoperatif dönemdeki analjezik tüketimi ve stres yanıt üzerine etkilerini belirlemek amaçlandı. Alt batın operasyonu uygulanacak ASA I-II grubuna giren 60 hasta rasgele üç gruba ayrıldı. Grup I’e indüksiyondan 5 dk. önce 5 mg iv morfin, Grup II’ye indüksiyondan 5 dk önce 0,5 mg intratekal morfin, Grup III’e indüksiyondan 30dk önce 5mg epidural morfin uygulandı. Anestezi indüksiyonu 0,1 µg kg-1 fentanil ve 4-7 mg k...

  9. EKSENEL PİSTONLU POMPA VE MOTORLARDA KAYICI PAPUÇ PERFORMANS ARAŞTIRMASI-AKIŞ VE VİSKOZ GÜÇ KAYBI

    Directory of Open Access Journals (Sweden)

    A. Osman KURBAN

    1997-01-01

    Full Text Available Bu çalışmada, hidrostatik-hidrodinamik yatakların iyi bir uygulama alanı olan, eğik plakalı eksenel pistonlu pompa ve motorların performansı üzerinde etkili olan kayıcı pabuçlar incelenmiştir. Bununla ilgili olarak viskoz moment kayıpları, viskoz akışkan kaçağı ve güç kayıp denklemleri elde edilip, değişik çalışma ortamlarında bu karakteristik parametrelerin değişimi ve mukayesesi deneysel olarak incelenmiştir.

  10. Ekşi Hamurlardan Laktik Asit Bakterileri ve Mayaların İzolasyonu ve Tanımlanması

    OpenAIRE

    Bakırcı, Fatih; Köse, Ergun

    2017-01-01

    Gıda tüketiminde önemli bir yere sahip olanekmeğin, son yıllarda raf ömrünü uzatmak ve besin kalitesini arttırmak içinzengin aroma ve doğal mikrofloraya sahip ekşi hamur ile üretimleri tercihedilmektedir. Bu çalışmada, İzmir ilinde bulunan 10 farklı yerel fırından alınan10 farklı ekşi hamur örneğinden izole edilen laktik asit bakteri (LAB) ve mayasuşlarının tanımlanması amaçlanmıştır. Ekşi hamur örneklerinden izole edilenmikroorganizmalar biyokimyasal özelliklerine göre Vitek 2 Compact (Biome...

  11. Tıbbi ve Aromatik Bitkilerin Antibakteriyel Aktivitesi ve Tekstil Sektöründe Kullanımı

    Directory of Open Access Journals (Sweden)

    Hülya KESİCİ GÜLER

    2015-11-01

    Full Text Available Özet: İnsanların doğala yönelmesi ile birlikte tıbbi ve aromatik bitkilere ilgi gün geçtikçe artmaktadır. Tıbbi aromatik bitkiler, hastalıkları önlemek ve iyileştirmek, sağlığı devam ettirmek için insanlık tarihinin başlangıcından beri ilaç olarak kullanılan bitkilerdir. Bu bitkilerin kullanımları ilaç, gıda, meşrubat, kozmetik sanayi, sabun ve parfüm üretiminde sınırlı kalmamış, günümüzde organik tarım ve hayvancılıkta kullanımları artış göstermektedir. Ayrıca günümüzde farklı özelliklerinden dolayı birçok sektörde de kullanılmaya başlanmıştır. Bunlardan bir tanesi de tekstil sektörüdür. Tıbbi ve aromatik bitkiler barındırdıkları antibakteriyel özellik sayesinde sentetik tekstil bitim maddelerine alternatif oluşturmaktadır. Tekstilde kullanılacak antibakteriyel maddelerden beklenen en önemli özelliklerden bir tanesi kullanılan maddenin insan ve çevre sağlığını olumsuz etkilememesi ve tekstil mamulünün diğer özelliklerini olumsuz yönde değiştirmemesidir. Bu nedenle son yıllarda çevre dostu ve doğal esaslı antibakteriyel maddelerin eldesi ve tekstil uygulamalarına olan ilgi hızla artmaktadır. Buna bağlı olarak yapılan çalışmada; tıbbi ve aromatik bitkilerin antibakteriyel aktivitesinin çeşitli yöntemlerle belirlenmesi ve tekstil sektöründe antibakteriyel bitim maddesi olarak kullanımı araştırılmıştır. Anahtar kelimeler: Tıbbi ve aromatik bitkiler, antibakteriyel aktivite, tekstil Antibacterial Activity of Medicinal and Aromatic Plants and Utilization in Textile Industry Abstract: Interest in medicinal and aromatic plants increases along with day by day with natural demands of people. Medicinal and aromatic plants, that are used for protecting and healing illness, and continving the human health, since the beginning of humanity. These plants are used not only in medicine, food, beverage, cosmetic industry, soap and perfume

  12. Almancada ve Türkçede Davetiye Örneklerinin Biçim, İçerik ve Dil İşlevi Açısından Karşılaştırmalı Olarak İncelenmesi Comparative Analysis of Invitation Card Samples in Terms of Design, Text Type and Linguistic Function in German and Turkish

    Directory of Open Access Journals (Sweden)

    Faik ÖMÜR

    2012-09-01

    Full Text Available In this study, some samples that are selected from the wedding circumcision and baptism invitation cards in German and Turkish out of the ones related to special days, that carry religious and national features, and that play a significant place in one’s individual and social life are analyzed. Some of these cards are selected among collected invitation cards and the rest from the most frequently used cards on the internet. Texts, laconic statements and other statements in Turkish cards are translated into German. The lines in the texts carry verse caharacteristics; therefore, they cannot be translated word for word stylistically. For that reason, considering cohesion and meaning equivalance, the translation is given as a table. Since there are not many studies conducted on invitation cards in Turkish and German, this study is thought to fill a significant gap. The scope of the invitation cards is limited to specific issue and standpoint. The study is handled in terms of socio-cultural and sociolinguistic point. Invitation cards that have the feature of pragmatic text are analyzed in terms of content, style and linguistic function. The study consists of four parts. In the first part, invitation card text definitions are given. In the second part, Turkish circumcision and wedding invitation card and German baptism and wedding invitation card samples are selected. In the third part, sample cards are compared in terms of design, text type, language and content. In the last part, the similarities and differences between these cards in terms of cultural, intercultural, economic, foreign language teaching, literary aspect, historical development and change are put forth. Bu çalışmada insanın bireysel ve sosyal hayatında önemli bir yere sahip olan, dini ve milli özellikler taşıyan belirli günlerle ilgili davetiyelerden Almancada ve Türkçede evlenme, sünnet ve vaftiz davetiyelerinden seçilmiş bazı örnekler karşılaştırmalı olarak

  13. Influence of different fertilizer supplements on decomposition of cereal stubble remains in chernozem soil

    Science.gov (United States)

    Nikolaev, I. V.; Klein, O. I.; Kulikova, N. A.; Stepanova, E. V.; Koroleva, O. V.

    2009-04-01

    Introduction Recently, many farmers have converted to low-disturbance tillage land cultivation as disk or plow fields can result in water and wind erosion of soil. So, crop residue and plant crowns and roots are left to hold the soil. However, low-disturbance tillage can be a challenge to manage since the key to crop production still requires good seed-to-soil contact. Therefore, decomposition of stubble in agricultural soils in situ is an issue of the day of modern agriculture. The aim of the present study was to compare different organic and inorganic fertilizer supplements on decomposition of cereal stubble remains in chernozem soil. Materials and methods Field trials were conducted in Krasnodar region, Russia. To promote stubble decomposition, a biopreparation that was cultural liquid obtained during cultivation of white-rot fungi Coriolus hirsutus 075 (Wulf Ex. Fr.) Quel. was used at the dosage of 150 ml/ha. The other tested supplements included ammonium nitrate (34 kg/ha), commercially available humate LignohumateTM (0.2 kg/ha) and combination of Lignohumate and biopreparation. Test plots were treated once after wheat harvesting. Non-treated ploughed plot was used as a blank. Soil samples were collected within 2 and 14 weeks after soil treatment. To control soil potential for stubble remains decomposition enzymatic activity is soil was determined. To perform soil analysis, stubble remains were carefully separated from soils followed by soil extraction with 0.14 M phosphate buffer pH 7.1 and analysis of the extracts for laccase and peroxidase activities [1,2]. Estimation of stubble decomposition in soil was performed by cellulose contents determination [3]. Results and discussion The obtained results demonstrated after 14 weeks of treatment increase of soil enzymatic activity due to soil supplementation was observed. Introduction of ammonium nitrate resulted in 108% of peroxidise activity as compared to blank. That value for Lignohumate variant was estimated

  14. Süt ve Ürünlerinde CO2 Uygulamaları – II: Çiğ ve Pastörize Süt

    Directory of Open Access Journals (Sweden)

    Enes Dertli

    2015-02-01

    Full Text Available Ürünlerin üretiminde hammaddeden kaynaklanan başlangıç bakteriyel yükün azaltılması, pastörizasyon sisteminin geliştirilmesi ve üretim işlemlerinden önceki kontaminasyonun önlenmesi gibi uygulamalar raf ömrünün uzatılmasında etkilidir. Karbon dioksit doğal olarak meydana gelen bir süt bileşenidir ve kesin mekanizması henüz anlaşılamamasına rağmen, ürünlerde bazı bozulma oluşturan mikroorganizmalara karşı inhibitör etkilidir. Uygulamada kullanılan yeni CO2 teknolojileri çiğ ve pastörize sütü içeren sütçülük ürünlerinde farklılığın artırılması, raf ömrünün ve kalitenin yükseltilmesi amacıyla sürekli geliştirilmektedir. Bu çalışmada CO2 kullanılarak çiğ ve pastörize sütün kalitesinin geliştirilmesi konusunda geçmişteki ve günümüzdeki araştırmalar detaylı olarak irdelenmiştir.

  15. NEVRUZ VE SUMER BEREKET KÜLTÜ AYNI KAYNAK DEĞİL Mİ?

    OpenAIRE

    ÇIĞ, Muazzez İlmiye

    2016-01-01

    Sumerliler insanlık tarihinin en eski kavimleri arasında yer almaktadır. Başta “yazı” olmak üzere kültür ve uygarlık simgesi birçok buluşun da Sumerlilere ait olduğu bilinmektedir. Türkler de tıpkı Sumerliler gibi insanlık tarihinin en eski kavimleri arasında yer almaktadır. Bu durum beraberinde “Peki Sumerliler ve Türkler arasında bir bağ var mıdır?” sorusunu akla getirmektedir. Başta Sumer belgeleri olmak üzere birçok bilgi ve belge Sumerliler ve Türkler arasında yakın bir...

  16. Semiyoloji ve Semiyotik Üzerine Düşünceler

    OpenAIRE

    Çiçek, Mehmet

    2016-01-01

    Türkçede Göstergebilim diye tek sözcükle karşılanan kavram Fransızca ve İngilizcede iki sözcükle karşılanmaktadır: Semiyoloji ve Semiyotik (Fr. Sémiologie; Sémiotique / İng. Semiology; Semiotics). Semiyoloji ve Semiyotik aynı şeyler midir, farklı şeyler mi? Biz bu kavramların eş anlamlı değil; olsa olsa yakın anlamlı olabileceklerini düşünüyoruz. Bu makalede bu kavramlar ve bu kavramlara ilişkin görüşler irdelenecektir.

  17. A vitamini ve anne çocuk sağlığı Derleme

    OpenAIRE

    Günlemez, Ayla; Atasay, Begüm; Arsan, Saadet

    2014-01-01

    A vitamini normal görmede hücre farklılaşmasında çoğalmasında ve epitelial bütünlüğün sağlanmasında kritik rol oynar Gelişmekte olan ülkelerde A vitamini eksikliği önemli ve önlenebilir halk sağlığı sorunlarından biridir Bu makalede dünyada ve Türkiye’de A vitamini eksikliği ve anne çocuk sağlığı üzerine etkileri tartışılmaktadır Anahtar Kelimeler: A vitamini anne sağlığı çocuk sağlığıSummaryVitamin A has a critical role in normal vision cell differantiation proliferation and maintanence of e...

  18. PERİFERİK KAN KÜLTÜRÜ VE YÖNETİMİ

    OpenAIRE

    ARDAHAN SEVGİLİ, SEDA; YARDIMCI, FİGEN

    2018-01-01

    Başlık: PERİFERİK KAN KÜLTÜRÜ VE YÖNETİMİTitle: PERIPHERALBLOOD CULTURE AND MANAGEMENTÖzet: Kandolaşımı enfeksiyonları; enfeksiyona neden olan mikroorganizma ile etkilediğicanlı arasında birçok etkileşim sonucunda meydana gelen ve oldukça karmaşık birsüreçtir. Bundan dolayı kan dolaşımı enfeksiyonlarının erken dönemdetanılanması ve tanısına yönelik tedavisinin başlatılması yaşamsal önemtaşımaktadır. Kan kültürleri; ciddi kan dolaşımı enfeksiyonlarının tanımlanmasıve...

  19. Bibliometrický seminář ve Vídni

    Czech Academy of Sciences Publication Activity Database

    Laiblová Kadlecová, Ivana

    -, č. 2 (2012) E-ISSN 1805-2800 Keywords : bibliography databases * bibliometrics * citation indexes * Web of Science * Austria http://www.lib.cas.cz/casopis-informace/bibliometricky-seminar-ve-vidni/

  20. Ozonla pestisit giderimi uygulamasının domateste renk ve C vitaminine etklieri

    OpenAIRE

    BALTACI YİĞİT, Havva Merve

    2015-01-01

    Bu tez kapsamında tarla koşullarında yetiştirilen domatesler üç farklı pestisit (neonikotinoidlerden imidacloprid, METI grubundan fenazaquin ve sentetik piretroidlerden lambda cyhalothrin) ile ilaçlanmış ve hasat edilen domateslerde yapılan ozonlama işleminin pestisit giderimine, C vitaminine ve renge etkisi ortaya konulmuştur. Ozonlu su ile yıkama işlemi sonucunda imidacloprid, fenazaquin ve lambda cyhalothrinin sırasıyla; %40,9, %57,8, %20,4 oranında, doğrudan suda yıkama işlemi so...

  1. Tıpta işbirliği ve hukuksal sorunlar

    OpenAIRE

    Rosenau, Henning

    2010-01-01

    Tıpta işbirliği ve hukuksal sorunlar : tarih: 16-17 nisan 2010, Kurupelit Yerleskesi, Samsun = Delegation und Kooperation im Gesundheitswesen / ed.: Henning Rosenau ... - Samsun : Adalet, 2010. - XII, 331 S.

  2. Laktoperoksidaz Sistemin Aktivasyonuyla ve Soğutularak Korunan Sütlerin Mikrobiyolojik Özellikleri

    Directory of Open Access Journals (Sweden)

    Zerrin Erginkaya

    2015-02-01

    Full Text Available Araştırmada, 12:8 mg/l ve 24:16 mg/l Tiyosiyanat: Hidrojenperoksit (SCN:H2O2 ilavesi ile laktoperoksidaz sistemi aktive edilen sütler 30°C'de 6 saat süreyle bekletilmişlerdir. Soğutularak 4±1°C'de tutulan, ayrıca kontrol olarak da SCN:H2O2 katılmamış ve 30°C'de tutulan süt örnekleri de aynı süre bekletilmişlerdir. Bekletmenin 0., 3. ve 6. saatlerinde sütün pH değeri, asittik derecesi ve bazı mikroorganizma grubu içeriklerindeki değişimler incelenmiştir. Laktoperoksidaz sisteminin aktivasyonunun, sütlerin toplam aerob mezofil ve psikrotrof bakteri gruplarının, mezofil ve termofil laktik asit bakteri gruplarının, enterobakterlerin ve küf-mayaların gelişimini önemli düzeyde etkilediği görülmüştür (p<0,05. Soğutmanın da toplam aerob psikrotrof bakteriler dışında, incelenen diğer tüm mikroorganizma gruplarını önemli düzeyde etkilediği bulunmuştur. SCN:H2O2 konsantrasyonunun artmasının, sistemin antimikrobiyel etkisini artırdığı belirlenmiştir. Laktoperoksidaz sisteminin aktivasyonunun soğutma kadar etkin olduğu, toplam aerob mezofil ve psikrotrof bakterilerle, enterobakterler üzerinde soğutmadan daha fazla etkili olduğu görülmüştür. Soğutma işlemi ve laktoperoksidaz sisteminin aktivasyonu, sütlerin pH ve asitlik değerleri üzerinde önemli ve yaklaşık aynı düzeyde etkili bulunmuştur (p<0,05.

  3. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 8 décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium The Galaxy in a new light: High energy gamma ray astronomy with H.E.S.S. Prof. Werner Hofmann / MPI für Kernphysik, Heidelberg During its first years of operation, the H.E.S.S. array of imaging atmospheric Cherenkov telescopes has revealed a sky full of sources of very high energy gamma rays and has demonstrated the great power of the Cherenkov technique for exploring non-thermal processes in the Universe. High-energy gamma ray astronomy is now delivering sky maps, sources with resolved morphology, and high-resolution light curves, joining up with mainstream astronomy. The talk will illustrate some of the key results from H.E.S.S., mention some of the open questions, and present ideas for the next-generation CTA observatory. Organizer : Prof. Markus Büttiker W...

  4. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Wednesday 17 décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Bent crystals: a long story and its new frontiers by Dr Michela Prest / Universita degli Studi dell’Insubria, sede di Como When a particle physicist hears the world "crystal", he usually thinks of calorimeters, silicon detectors, a state of matter. When he hears the word "magnet", he thinks of bulky, heavy objects. In 1976, E. H. Tsyganov experimentally demonstrated how a bent crystal 1 mm thick, a couple of mm wide and a few cm high can steer particles as a dipole of several tens of Tesla. Crystals and the channelling phenomena have been studied for around 30 years. Hadron beam collimation has been immediately identified as their main application and the understanding of the physics of crystals and their experimental stu...

  5. The VULCANO VE-U7 Corium spreading benchmark

    Energy Technology Data Exchange (ETDEWEB)

    Journeau, Christophe; Haquet, Jean-Francois [CEA Cadarache, Severe Accident Mastering experimental Laboratory (DEN/DTN/STRI/LMA), 13108 St Paul lez Durance (France); Spindler, Bertrand [CEA Grenoble, Physicochemistry and Multiphasic Thermalhydraulics Laboratory (DEN/DTN/SE2T/LPTM), 17 rue des Martyrs, F-38054 Grenoble CEDEX 9 (France); Spengler, Claus [Gesellschaft fuer Reaktorsicherheit mbH, Department for Thermohydraulics/Process Engineering, Schwertnergasse 1, D-50667 Koeln (Germany); Foit, Jerzy [Forschungszentrum Karlsruhe GmbH, Institut fuer Kern nd Energietechnik (IKET), P.O. Box 3640, D-76021 Karlsruhe (Germany)

    2006-07-01

    In a hypothetical nuclear reactor severe accident, corium spreading is one possible mitigation measure that has been selected for the EPR design. A post-test benchmark exercise has been organized on the VULCANO VE-U7 corium spreading experiment. In this test, a prototypic corium mixture representative of what could be expected at the opening of EPR reactor-pit gate has been spread on siliceous concrete and on a reference channel in inert refractory ceramic. The spreading progression was not much affected by the presence of concrete and sparging gases. The procedure used to estimate the corium physical properties from its composition and temperature provided a satisfactory data set. The CORFLOW, LAVA and THEMA codes provide satisfactory calculations of the spreading front evolution and of its final length. LAVA and THEMA estimations of the substrate temperatures, which are the initial conditions for longer term Molten Core Concrete Interaction or Corium Ceramic Interaction computations, are also close to the measured data, within the experimental uncertainties. (authors)

  6. The VULCANO VE-U7 Corium spreading benchmark

    International Nuclear Information System (INIS)

    Journeau, Christophe; Haquet, Jean-Francois; Spindler, Bertrand; Spengler, Claus; Foit, Jerzy

    2006-01-01

    In a hypothetical nuclear reactor severe accident, corium spreading is one possible mitigation measure that has been selected for the EPR design. A post-test benchmark exercise has been organized on the VULCANO VE-U7 corium spreading experiment. In this test, a prototypic corium mixture representative of what could be expected at the opening of EPR reactor-pit gate has been spread on siliceous concrete and on a reference channel in inert refractory ceramic. The spreading progression was not much affected by the presence of concrete and sparging gases. The procedure used to estimate the corium physical properties from its composition and temperature provided a satisfactory data set. The CORFLOW, LAVA and THEMA codes provide satisfactory calculations of the spreading front evolution and of its final length. LAVA and THEMA estimations of the substrate temperatures, which are the initial conditions for longer term Molten Core Concrete Interaction or Corium Ceramic Interaction computations, are also close to the measured data, within the experimental uncertainties. (authors)

  7. Talent management ve vybrané společnosti

    OpenAIRE

    Šimonová, Lucie

    2015-01-01

    Tato diplomová práce se zaměřuje na oblast Talent managementu, přičemž její první část je věnována předložení teoretických poznatků, které se týkají vymezení a popisu základních pojmů jako je „talent“, „Talent management“ či „motivace“. Tyto poznatky jsou následně využity při zpracování části praktické, a to ve spolupráci s vybranou společností, jež má o zavedení Talent managementu zájem. This master’s thesis is focused on Talent management. First part is devoted to theoretical knowledge w...

  8. Time Remains

    OpenAIRE

    Gryb, Sean; Thebault, Karim

    2014-01-01

    On one popular view, the general covariance of gravity implies that change is relational in a strong sense, such that all it is for a physical degree of freedom to change is for it to vary with regard to a second physical degree of freedom. At a quantum level, this view of change as relative variation leads to a fundamentally timeless formalism for quantum gravity. Here, we will show how one may avoid this acute 'problem of time'. Under our view, duration is still regarded as relative, but te...

  9. LANCHESTER DOĞRUSALLIK KANUNU VE BİR PAZARLAMA UYGULAMASI

    OpenAIRE

    YARALIOĞLU, KAAN

    2001-01-01

    Bu çalışmada birebir mücadeleler için geliştirilen Lanchester’ in Doğrusallık Kanunu incelenmiştir. Öncelikle formülasyon ve kullanılabilirlik koşulları tanımlanmış ve bir pazarlama uygulaması gerçekleştirilmiştir.

  10. Digital Content Strategies

    OpenAIRE

    Halbheer, Daniel; Stahl, Florian; Koenigsberg, Oded; Lehmann, Donald R

    2013-01-01

    This paper studies content strategies for online publishers of digital information goods. It examines sampling strategies and compares their performance to paid content and free content strategies. A sampling strategy, where some of the content is offered for free and consumers are charged for access to the rest, is known as a "metered model" in the newspaper industry. We analyze optimal decisions concerning the size of the sample and the price of the paid content when sampling serves the dua...

  11. Slow Learner Prediction Using Multi-Variate Naïve Bayes Classification Algorithm

    Directory of Open Access Journals (Sweden)

    Shiwani Rana

    2017-01-01

    Full Text Available Machine Learning is a field of computer science that learns from data by studying algorithms and their constructions. In machine learning, for specific inputs, algorithms help to make predictions. Classification is a supervised learning approach, which maps a data item into predefined classes. For predicting slow learners in an institute, a modified Naïve Bayes algorithm implemented. The implementation is carried sing Python.  It takes into account a combination of likewise multi-valued attributes. A dataset of the 60 students of BE (Information Technology Third Semester for the subject of Digital Electronics of University Institute of Engineering and Technology (UIET, Panjab University (PU, Chandigarh, India is taken to carry out the simulations. The analysis is done by choosing most significant forty-eight attributes. The experimental results have shown that the modified Naïve Bayes model has outperformed the Naïve Bayes Classifier in accuracy but requires significant improvement in the terms of elapsed time. By using Modified Naïve Bayes approach, the accuracy is found out to be 71.66% whereas it is calculated 66.66% using existing Naïve Bayes model. Further, a comparison is drawn by using WEKA tool. Here, an accuracy of Naïve Bayes is obtained as 58.33 %.

  12. Surke'nin Bazı Kimyasal ve Mikrobiyolojik Kalite Nitelikleri

    Directory of Open Access Journals (Sweden)

    Ufuk Kamber

    2015-02-01

    Full Text Available Bu çalışma, Hatay ilinde tüketilen ve halk arasında Surke peyniri olarak kabul edilen süt ürününün bazı kimyasal ve mikrobiyolojik özeliklerini ortaya koymak ve Surke' yi tanıtmak amacıyla yapılmıştır. On örnek üzerinde yapılan analizlerde Surke peynirinde ortalama mikrobiyolojik analiz sonuçları sırasıyla toplam aerob mezofil bakteri; 6.5x108 kob/g, laktobasiller 4.4x107kob/g, laktokoklar 2.8x102 kob/g, mikrokok ve stafilokoklar 2.5x102 kob/g, enterobakteriler 3.5x102 kob/g, koliform grubu bakteriler <2.0x102kob/g, ve maya/küf ise 2.7x105 kob/g düzeyinde izole edilmiştir. Kimyasal analiz bulgularına göre ortalama; peynirlerde kuru madde miktarı % 52.8, yağ % 11.0, tuz % 8.1 ve asitlik laktik asit (LA cinsinden % 2.1 olarak saptanmıştır.

  13. TABLE OF CONTENTS EDUCATION

    Directory of Open Access Journals (Sweden)

    Vanderbilt Dikkat Eksikliği

    2013-12-01

    Full Text Available Tüketicilerin Çoklu Ünlü Kullanılan Reklamlara Karşı Tutumlarında Cinsiyetin Rolü Işık Özge YUMURTACI, Tuğba ÖRTEN TUĞRUL, Bengü Sevil OFLAÇ Türkiye’de Savunma Harcamaları, Büyüme ve Gelir Eşitsizliği, 1970-2008: Ekonometrik Bir İnceleme Seyhan TAŞ, İbrahim ÖRNEK, Gül AKSOĞAN SOCIOLOGY İmal Edilmiş Belirsizlikler Çağının Sosyolojik Yönelimi: Ulrıch Beck ve Anthony Giddens Kaynaklı “Risk Toplumu” Tartışmaları Ali ESGİN HISTORY 1849 Rus Kafkas Yılığına Göre Kafkasya’da Çarlık Rusya İdaresindeki Yerleşim Yerleri Şahin DOĞAN

  14. Streptococcus azizii sp. nov., isolated from naïve weanling mice.

    Science.gov (United States)

    Shewmaker, Patricia Lynn; Whitney, Anne M; Gulvik, Christopher A; Lipman, Neil S

    2017-12-01

    Three isolates of a previously reported novel catalase-negative, Gram-stain-positive, coccoid, alpha-haemolytic, Streptococcus species that were associated with meningoencephalitis in naïve weanling mice were further evaluated to confirm their taxonomic status and to determine additional phenotypic and molecular characteristics. Comparative 16S rRNA gene sequence analysis showed nearly identical intra-species sequence similarity (≥99.9 %), and revealed the closest phylogenetically related species, Streptococcus acidominimus and Streptococcuscuniculi, with 97.0 and 97.5 % sequence similarity, respectively. The rpoB, sodA and recN genes were identical for the three isolates and were 87.6, 85.7 and 82.5 % similar to S. acidominimus and 89.7, 86.2 and 80.7 % similar to S. cuniculi, respectively. In silico DNA-DNA hybridization analyses of mouse isolate 12-5202 T against S. acidominimus CCUG 27296 T and S. cuniculi CCUG 65085 T produced estimated values of 26.4 and 25.7 % relatedness, and the calculated average nucleotide identity values were 81.9 and 81.7, respectively. These data confirm the taxonomic status of 12-5202 T as a distinct Streptococcus species, and we formally propose the type strain, Streptococcusazizii 12-5202 T (=CCUG 69378 T =DSM 103678 T ). The genome of Streptococcus azizii sp. nov. 12-5202 T contains 2062 total genes with a size of 2.34 Mbp, and an average G+C content of 42.76 mol%.

  15. FEMİNİST ULUSLARARASI İLİŞKİLER VE ULUSLARARASI İLİŞKİLER ELEŞTİRİSİ: CİNSİYET, DEVLET VE GÜVENLİK

    OpenAIRE

    DOĞAN, Fazlı; ÖZLÜK, Duygu

    2016-01-01

    Bu çalışma bir sosyal ve politik teori olarak Feminizm’in Uluslararası İlişkilere (Uİ) girişi ve Feminist Uİ’nin ana akım Uİ teorilerine cinsiyet, devlet ve güvenlik başlıkları üzerinden yönelttiği eleştirileri değerlendirmektedir. Üç ana bölümden oluşan çalışmada öncelikle bir sosyal ve politik teori ve bir hareket olarak feminizmin tarihsel gelişimi kısaca tartışılmıştır. İkinci bölümde feminist hareketlerin uluslararası ilişkilerdeki gelişimi ve bir Uİ teorisi olarak Feminist Uİ’nin genel ...

  16. Éra opoziční smlouvy ve světle veřejného mínění

    Czech Academy of Sciences Publication Activity Database

    Červenka, Jan

    2016-01-01

    Roč. 14, č. 2 (2016), s. 17-32 ISSN 1214-438X Institutional support: RVO:68378025 Keywords : Czech Republic * opposition agreement * minority government Subject RIV: AD - Politology ; Political Sciences OBOR OECD: Sociology https://cvvm.soc.cas.cz/cz/casopis-nase-spolecnost/prehled-clanku/133-2016-2/4341-era-opozicni-smlouvy-ve-svetle-verejneho-mineni

  17. İçme ve sulama sularında bor kirliliği ve bor giderme yöntemleri

    Directory of Open Access Journals (Sweden)

    Meltem Bilici Başkan

    2014-03-01

    Full Text Available Periyodik cetvelin 3A grubunda yer alan bor yüksek iyonlaşma potansiyeline sahip olması nedeniyle yarı metal olarak kabul edilir. Yerkabuğundaki ortalama bor konsantrasyonu 10 mg/kg'dır. Bor doğada Ca, Na ve Mg'un tuzları şeklinde bulunur. Yüksek konsantrasyonlarda ve ekonomik boyutlardaki bor yatakları; borun oksijen ile bağlanmış bileşikleri şeklinde daha çok Türkiye ve ABD'nin kurak, volkanik ve hidrotermal aktivitesi olan bölgelerinde bulunmaktadır. Bor, bitkiler için gerekli bir mikro besin elementi olmanın yanı sıra, gerekli tüm besin elementleri içerisinde, eksiklik belirtilerine neden olan miktarı ile toksik etki yapan miktarı, birbirine çok yakın olan tek elementtir. Bor su ortamında genellikle borik asit ve kısmen de borat tuzları formlarında bulunmaktadır. Pek çok endüstride kullanım alanı bulan bor bileşiklerinin endüstriyel gelişmelere bağlı olarak yüzeysel sularda bulunan konsantrasyonu artış göstermektedir. Yüzeysel sularda bulunan bor aynı zamanda evsel atıksulardan da kaynaklanmaktadır. Türkiye'de içme ve sulama sularını en çok kirleten toksik elementlerin başında bor gelmektedir. Bu nedenle bor giderimi hem insan sağlığı açısından hem de sağlıklı tarım ürünü yetiştirilebilmesi açısından oldukça önemlidir. Sulardan bor giderimi için uygulanan temel yöntemler arasında iyon değişimi, ultrafiltrasyon, ters osmoz ve adsorbsiyon gelmektedir.

  18. Küf Koleksiyonlarının Oluşturulması ve Korunumu

    Directory of Open Access Journals (Sweden)

    Şeminur Topal

    2015-02-01

    Full Text Available Çeşitli amaçlarla saf küf kültürlerinin uygun koşullarda ve özgün karakterlerini değiştirmeden korunmasını esas alan küf koleksiyonunun varlığı pek çok durum ve kuruluşun çalışmalarına destek sağlayabilir. Bu gerçekten hareketle NATO destekli ve 6 yıl süren Türkiye’de çeşitli tarımsal ürün ve gıdaların tarladan-tüketime kadarki küf floralarının taranmasına yönelik proje çalışmasında izole ve identifiye edilen küflerin bir koleksiyon bünyesinde değerlendirilmesi planlanmıştır. Pek çoğu, önemli dış koleksiyon merkezleri olan CBS-Hollanda ve CMI-İngiltere’deki uzmanların teyidini alan ve identifikasyonları tarafımızdan yapılan 10.000 civarındaki küf izolatından duplikasyon yaratabilecekleri elemine edilmiş, diğerleri korunuma alınmıştır. Yatık ve liyofilize kültürler olarak koleksiyonda bulunan küf suşlarının büyük bir kısmı için sistematik arşivleme çalışması tamamlanmış ve bilgisayar yardımı ile sınıflandırılmıştır. Bu sınıflama mevcut küflerin, izole edildiği örnek cinsi ve kayıt numaralarına, sağlandığı bölgelerin il trafik kod numaralarına, küf kültürlerinin cins ve tür isimlerine, liyofilize numaralarına ve koleksiyon odasındaki konumunun yer numaralarına göre olmak üzere 6 ayrı parametre için tek tek yapılarak arşivleme gerçekleştirilmiştir. Ayrıca identifiye edilen küflerin cins ve türlerine göre kartoteksleme işlemi yapılmıştır. Bu çalışmada koleksiyon ve korunumuna ilişkin ayrıntılı bilgiler verilmiştir.

  19. Modern ve Postmodern Değerlerin Yabancılaşmaya Etkisi

    Directory of Open Access Journals (Sweden)

    Mahmut ŞAYLIKAY

    2016-08-01

    Full Text Available Bilindiği üzere, yabancılaşma, kişinin kendi benliğinden, çevresinden ve sosyalyaşamdan uzaklaşarak bu kavramların etkisi altına girmek olarak tanımlanabilir. Buyönüyle yabancılaşma, sendikalaşmaya hizmet etmesi açısından son derece önemlidir.Diğer taraftan modern ve post modern değerlerin sendikalaşmaya etkisi ise, bireyin belirlibir sendikayla özdeşleşmesi, sendikaya bağlılığı ve kendini adamasıdır. „‟Modernizationand postmodernization: Cultural, economic and political change in 43 societies„‟ adlıçalışmasıyla, Inglehart (1997, „‟Post modern Values in Seven Confucian Societies:Political Consequences of Changing World Views‟‟ adlı çalışmasıyla Wang(2007 ve ‘’Alienation and freedom: The factory worker and his industry.‟‟ adlı çalışmasıyla Blauner(1964 modern - post modern değerler ve yabancılaşma kavramlarına ilişkin literatüre katkısağlamışlardır. Bu çalışmada, sendika üyesi işçilere yönelik söz konusu değişkenlerarasındaki ilişki ve ilişkinin boyutu araştırılmaktadır. Çalışma sayesinde sendika üyelerininsahip oldukları modern ve post modern değerlerinin sosyal yaşama etkileri ve yabancılaşmaboyutlarına göstermiş olduğu tutum ve davranışlar ortaya koyularak sonuçlarıpaylaşılmıştır. Bu bağlamda, çalışmanın temel amacı, sendika üyeleri temelinde, ilişki veetkiler bakımından modern ve post modern değerlerin yabancılaşma ile ilişkisini ele alıp,sendika üyelerinin “yabancılaşma” davranışında bulunma algılarını yapılan araştırmabulgularıyla ortaya koymaktır. Araştırmada, birincil veri toplama yöntemlerinden yüz yüzeanket yöntemi gerçekleştirilmiş ve modern-post modern değerler için, Inglehart‟ın(1997,Fries ve arkadaşları (2007 ve Wang (2007 tarafından geliştirilen modernizm-postmodernizm ölçeği kullanılmıştır. Yabancılaşma ölçeği olarak Blauner‟s (1964 taraf

  20. Bafa Gölü'nde biyotik ve abiyotik ortamda pestisit ve pcb dağılımı.

    Directory of Open Access Journals (Sweden)

    İdil Pazı

    2015-12-01

    Full Text Available Çalışma kapsamında Bafa Gölü’nden alınan sediment ve kefal balığı (Mugil cephalus, Linnaeus 1758 örneklerinde tarımsal pestisit ve endüstriyel kaynaklı PCB gibi organik kirleticilerin kalıntıları ölçülmüş ve bu bileşiklerin dağılımları, muhtemel kaynakları ve potansiyel biyolojik riskleri incelenmiştir. DDT ve türevleri açısından dünyanın farklı bölgelerindeki göllerin yüzey sedimentleri ile kıyaslandığında Bafa Gölü sedimentlerinde DDT kirlilik seviyesinin oldukça düşük olduğu bulunmuştur. Sedimentte Endrin baskın kirletici olarak belirlenmiştir. Sediment örneklerinde ölçülen DDT ve metabolitleri, Dieldrin, Lindan ve Heptaklor konsantrasyonları sediment kalite indekslerine göre değerlendirildiğinde, kirleticilerin göldeki canlı yaşamına olumsuz bir etkisinin olmadığı belirlenmiştir. ∑PCB konsantrasyonlarının ise göl kıyısında bulunan endüstriyel kuruluşlara yakın istasyonlarda sadece düşük değerli etki sevisini aşıp, diğer tüm istasyonlarda canlılar için risk yaratmayacağı belirlenmiştir. Mugil cephalus karaciğer dokusu için hesaplanan biyota sediment akümülasyon faktörü (BSAF 0.44-3.16 arasında değişmektedir. Bafa Gölü Mugil cephalus örneklerinde ölçülen kirletici konsantrasyonları dikkate alındığında Gıda ve Tarım Kurumu (FAO ve Dünya Sağlık Örgütüne (WHO göre Aldrin, Dieldrin, Endrin, Heptaklor ve DDT türevleri için hesaplanan Günlük Alım Miktarı değerlerinin (EDI Kabul Edilebilir Günlük Alım miktarlarının (ADI oldukça altında kaldığı belirlenmiştir. Ancak, balık örneklerindeki PCB seviyelerinin WHO tarafından belirlenen ADI değerini aştığı saptanmıştır

  1. Publishing and Revising Content

    Science.gov (United States)

    Editors and Webmasters can publish content without going through a workflow. Publishing times and dates can be set, and multiple pages can be published in bulk. Making an edit to published content created a revision.

  2. Increased circulating full-length betatrophin levels in drug-naïve metabolic syndrome.

    Science.gov (United States)

    Liu, Dan; Li, Sheyu; He, He; Yu, Chuan; Li, Xiaodan; Liang, Libo; Chen, Yi; Li, Jianwei; Li, Jianshu; Sun, Xin; Tian, Haoming; An, Zhenmei

    2017-03-14

    Betatrophin is a newly identified circulating adipokine playing a role in the regulation of glucose homeostasis and lipid metabolism. But its role in metabolic syndrome (MetS) remains unknown. Therefore, we aimed to compare the circulating betatrophin concentrations between patients with MetS and healthy controls. We recruited 47 patients with MetS and 47 age and sex matched healthy controls. Anthropometric and biochemical measurements were performed, and serum betatrophin levels were detected by ELISA. Full-length betatrophin levels in patients with MetS were significantly higher than those in controls (694.84 ± 365.51 pg/ml versus 356.64 ± 287.92 pg/ml; P <0.001). While no significant difference of total betatrophin levels was found between the two groups (1.20 ± 0.79 ng/ml versus 1.31 ± 1.08 ng/ml; P = 0.524). Full-length betatrophin level was positively correlated with fasting plasma glucose (FPG) (r = 0.357, P = 0.014) and 2-hour plasma glucose (2hPG) (r = 0.38, P <0.01). Binary logistic regression models indicated that subjects in the tertile of the highest full-length betatrophin level experienced higher odds of having MetS (OR, 8.6; 95% CI 2.8-26.8; P <0.001). Our study showed that full-length betatrophin concentrations were increased in drug-naïve MetS patients.

  3. [Choice of initial regimen for antiretroviral-naïve HIV patients: Analysis of motivation].

    Science.gov (United States)

    Rouveix, E; Mortier, E; Beauchet, A; Dupont, C; Gerbe, J; Daneluzzi, V; Brazille, P; Berthe, H; Zucman, D; Genet, P; Simonpoli, A-M; de Truchis, P

    2016-12-01

    Several therapeutic combination antiretroviral therapy regimen are available for initial treatment in naïve HIV infected patients. The choice of a particular regimen remains often subjective. The aim of this study was to determine factors associated with the choice of molecules in initial ARV prescriptions. From 01/01 to 30/10/2014, every initial cART prescription was analyzed regarding patients and physicians characteristics. Then, prescriptions were evaluated by an independent committee of ART prescribers. One hundred and thirty two consecutive initial prescriptions by 34 physicians of 11 medical centers were included: 71 M, migrants: 57 %, MSM: 21 %, CD4100 000 cp/mL (33 %). cART regimen were: NRTI/PI (43 %), NRTI/NNRTI (29.5 %), NRTI/integrase inhibitor (23 %). 75 % of initial cART regimen were consistent with expert guidelines recommendations. The choice of initial cART was not influenced by the type of HIV contamination risk group, patient's geographic origin, CD4 levels. In contrast, working or not (P=0.007), pregnancy wish (P=0.07), pregnancy (P=0.001), HIV RNA levels (P=0.02) and HIV primary infection (P=0.049) influenced the initial choice. Neither physician's age, nor physician's experience influenced this choice. The prescription's non accordance to 2013 French guidelines was mainly related to integrase inhibitor utilisation (P= 0.0001). Overall, cART initial choice is mostly consistent with guidelines. Primary HIV infection, procreation features and high viral load are the main factors influencing this choice. New regimen with better tolerability is prescribed even if it is not yet included in the guidelines. Copyright © 2016 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  4. Interfacing with in-Situ Data Networks during the Arctic Boreal Vulnerability Experiment (ABoVE)

    Science.gov (United States)

    McInerney, M.; Griffith, P. C.; Duffy, D.; Hoy, E.; Schnase, J. L.; Sinno, S.; Thompson, J. H.

    2014-12-01

    The Arctic Boreal Vulnerability Experiment (ABoVE) is designed to improve understanding of the causes and impacts of ecological changes in Arctic/boreal regions, and will integrate field-based studies, modeling, and data from airborne and satellite remote sensing. ABoVE will result in a fuller understanding of ecosystem vulnerability and resilience to environmental change in the Arctic and boreal regions of western North America, and provide scientific information required to develop options for societal responses to the impacts of these changes. The studies sponsored by NASA during ABoVE will be coordinated with research and in-situ monitoring activities being sponsored by a number of national and international partners. The NASA Center for Climate Simulation at the Goddard Space Flight Center has partnered with the NASA Carbon Cycle & Ecosystems Office to create a science cloud designed for this field campaign - the ABoVE Science Cloud (ASC). The ASC combines high performance computing with emerging technologies to create an environment specifically designed for large-scale modeling, analysis of remote sensing data, copious disk storage with integrated data management, and integration of core variables from in-situ networks identified by the ABoVE Science Definition Team. In this talk, we will present the scientific requirements driving the development of the ABoVE Science Cloud, discuss the necessary interfaces, both computational and human, with in-situ monitoring networks, and show examples of how the ASC is being used to meet the needs of the ABoVE campaign.

  5. Profiles of HIV-infected anti-retroviral therapy naïve children from Mumbai, India.

    Science.gov (United States)

    Paranjpe, Supriya Mayur; Sarkate, Purva Pankaj; Ingole, Nayana Avinash; Raut, Shweta Sadanand; Mehta, Preeti Rajeev

    2016-11-01

    This study aimed to investigate the demographic profiles of human immunodifficiency virus (HIV) infected anti-retroviral therapy (ART) naïve children in our hospital and their relations to the clinical, immunological and nutritional status. A cross-sectional study was conducted in an Integrated Counselling and Testing Center (ICTC) at a tertiary care hospital in Mumbai. ART naïve HIV positive children were enrolled in the study. The demographic profiles, clinical features, immunological (CD4%/CD4 count) and nutritional status of these children were recorded. The agreement between clinical, immunological and nutritional staging was determined using Cohen's kappa test. In 192 HIV-infected ART naive children enrolled with a median age of 9 years (range 3 months-14 years), 97.4% acquired infection through vertical transmission. The most common clinical presentation was fever (39.6 %), followed by generalized lymphadenopathy (32.3%), cough (22.4%) and diarrhoea (9.9%). Tuberculosis was seen in 22.9% of the children. The agreement was fair between clinical and immunological staging, and slight between nutritional, immunological and clinical staging. Perinatal transmission is the most common mode of acquiring HIV infection in children. The Prevention of Parent to Child Transmission (PPTCT) program should be strengthened for lowering the transmission rate by providing extended ART to mothers during pregnancy and breast-feeding. Tuberculosis remains a major concern in HIV-infected children. The poor correlation between WHO clinical and immunological staging emphasizes the importance of making CD4 facilities available in HIV prevalent areas. Malnutrition cannot be used as a surrogate marker for predicting stage or severity as it is common at all stages of HIV disease.

  6. Abiotic and Biotic Factors Regulating Inter-Kingdom Engagement between Insects and Microbe Activity on Vertebrate Remains

    Science.gov (United States)

    Jordan, Heather R.; Tomberlin, Jeffery K.

    2017-01-01

    A number of abiotic and biotic factors are known to regulate arthropod attraction, colonization, and utilization of decomposing vertebrate remains. Such information is critical when assessing arthropod evidence associated with said remains in terms of forensic relevance. Interactions are not limited to just between the resource and arthropods. There is another biotic factor that has been historically overlooked; however, with the advent of high-throughput sequencing, and other molecular techniques, the curtain has been pulled back to reveal a microscopic world that is playing a major role with regards to carrion decomposition patterns in association with arthropods. The objective of this publication is to review many of these factors and draw attention to their impact on microbial, specifically bacteria, activity associated with these remains as it is our contention that microbes serve as a primary mechanism regulating associated arthropod behavior. PMID:28538664

  7. Plasmaspheric electron content

    International Nuclear Information System (INIS)

    Hartmann, G.K.

    1978-01-01

    Measurements of the plasmaspheric electron content are reviewed with particular reference to the ATS-6 radio beacon experiment. From the review, it appears likely that measurement of the plasmaspheric electron content is the only one capable of monitoring electron fluxes continuously between L 1 and L 2. Some recent important results deduced from plasmaspheric electron content measurements are discussed

  8. Mechanisms of action of brief alcohol interventions remain largely unknown – A narrative review

    Directory of Open Access Journals (Sweden)

    Jacques eGaume

    2014-08-01

    Full Text Available A growing body of evidence has shown efficacy of brief intervention (BI for hazardous and harmful alcohol use in primary health care settings. Evidence for efficacy in other settings, and effectiveness when implemented at larger scale is disappointing. Indeed, BI comprises varying content, and exploring BI content and mechanisms of action may be a promising way to enhance efficacy and effectiveness.We searched Medline and PsychInfo, as well as references of retrieved publications for original research or reviews on active ingredients (or components, or mechanisms of face-to-face BIs (and its subtypes, including brief advice and brief motivational interviewing [BMI] for alcohol. Overall, BI active ingredients have been scarcely investigated, almost only within BMI, and mostly among Emergency Room patients, young adults, and US college students. This body of research has shown that personalized feedback may be an effective component; specific MI techniques showed mixed findings; decisional balance findings tended to suggest a potential detrimental effect; while change plan exercises, advice to reduce or stop drinking, presenting alternative change options, and moderation strategies are promising but need further study. Client change talk is a potential mediator of BMI effects; change in norm perceptions and enhanced discrepancy between current behavior and broader life goals and values have received preliminary support; readiness to change was only partially supported as a mediator; while enhanced awareness of drinking, perceived risks/benefits of alcohol use, alcohol treatment seeking, and self-efficacy were seldom studied and have as yet found no significant support as such.Research is obviously limited and has provided no clear and consistent evidence on the mechanisms of alcohol BI. How BI achieves the effects seen in randomized trials remains mostly unknown and should be investigated to inform the development of more effective interventions.

  9. Mechanisms of action of brief alcohol interventions remain largely unknown - a narrative review.

    Science.gov (United States)

    Gaume, Jacques; McCambridge, Jim; Bertholet, Nicolas; Daeppen, Jean-Bernard

    2014-01-01

    A growing body of evidence has shown the efficacy of brief intervention (BI) for hazardous and harmful alcohol use in primary health care settings. Evidence for efficacy in other settings and effectiveness when implemented at larger scale are disappointing. Indeed, BI comprises varying content; exploring BI content and mechanisms of action may be a promising way to enhance efficacy and effectiveness. Medline and PsychInfo, as well as references of retrieved publications were searched for original research or review on active ingredients (components or mechanisms) of face-to-face BIs [and its subtypes, including brief advice and brief motivational interviewing (BMI)] for alcohol. Overall, BI active ingredients have been scarcely investigated, almost only within BMI, and mostly among patients in the emergency room, young adults, and US college students. This body of research has shown that personalized feedback may be an effective component; specific MI techniques showed mixed findings; decisional balance findings tended to suggest a potential detrimental effect; while change plan exercises, advice to reduce or stop drinking, presenting alternative change options, and moderation strategies are promising but need further study. Client change talk is a potential mediator of BMI effects; change in norm perceptions and enhanced discrepancy between current behavior and broader life goals and values have received preliminary support; readiness to change was only partially supported as a mediator; while enhanced awareness of drinking, perceived risks/benefits of alcohol use, alcohol treatment seeking, and self-efficacy were seldom studied and have as yet found no significant support as such. Research is obviously limited and has provided no clear and consistent evidence on the mechanisms of alcohol BI. How BI achieves the effects seen in randomized trials remains mostly unknown and should be investigated to inform the development of more effective interventions.

  10. KADIN YOKSULLUĞU VE KADIN SAĞLIĞI ÜZERİNE YANSIMALARI

    Directory of Open Access Journals (Sweden)

    Seda KOCABACAK

    2014-08-01

    Full Text Available Cinsiyet eşitsizliği, yoksulluk ve iyi olmayan sağlık durumunun önemli nedenlerinden biridir. Kadınlar sosyal hayatın birçok alanında cinsiyet ayrımcılığı ile karşı karşıya kalırlar: sağlık hizmetlerinden yararlanma, eğitim, istihdam koşulları, sosyal ve ekonomik yaşam, politik haklar ve ahlaki sorumluluklar bunların bazılarıdır. Bazı toplumsal kabuller ya da ailelerin ekonomik zorlukları kız çocukların okuldan uzak kalmasına yol açabilmektedir. Eğitimsizlik ya da yetersiz eğitim ise özel nitelikler gerektirmeyen ya da düşük gelir sağlayan işlerde çalışılmasına yol açmaktadır. Bu kısıtlılıklar ve eşitsizlikler kadın sağlığı ve refahı üzerinde doğrudan ya da dolaylı etkilere sahiptir. Eğitimli ve refah sahibi kadınlar kadın sağlığı, çocuk sağlığı, aile sağlığı ve hatta tüm toplumun sağlığının geliştirilmesine katkı sağlarlar. Bu çalışmanın amacı ilk olarak kadın yoksulluğu ve sağlığı arasındaki ilişkiyi tartışmak ve Türkiye’ye ilişkin verilerle değerlendirmeler yapmaktır.

  11. Naturalising Representational Content

    Science.gov (United States)

    Shea, Nicholas

    2014-01-01

    This paper sets out a view about the explanatory role of representational content and advocates one approach to naturalising content – to giving a naturalistic account of what makes an entity a representation and in virtue of what it has the content it does. It argues for pluralism about the metaphysics of content and suggests that a good strategy is to ask the content question with respect to a variety of predictively successful information processing models in experimental psychology and cognitive neuroscience; and hence that data from psychology and cognitive neuroscience should play a greater role in theorising about the nature of content. Finally, the contours of the view are illustrated by drawing out and defending a surprising consequence: that individuation of vehicles of content is partly externalist. PMID:24563661

  12. Soğukta ve Dondurulmuş Halde Muhafazaları Esnasında Meyve ve Sebzelerin Kalite ve Besleyici Değerlerinde Meydana Gelen Değişiklikler

    Directory of Open Access Journals (Sweden)

    Osman Cabı

    2015-02-01

    Full Text Available Kolay bozulabilir gıda maddelerinin daha uzun süre muhafaza edilmeleri amacıyla soğutma yönteminin kullanılmasının geçmişi tarih öncesi zamanlara kadar uzanmaktadır. Adı geçen “muhafaza” veya “korunma” sözcüğü, Weiser ve ark. 1971 tarafından, bir gıda maddesinin fiziksel, kimyasal kalitelerinin ve besleyici özelliklerinin belli bir süre müddetince veya mümkün olduğu kadar uzun bir periyot süresince saklanması şeklinde tanımlanmaktadır. Soğuğun çeşitli uygulamalarıyla muhafaza edilen gıda maddeleri gerek kantite gerekse çeşit ve yapı olarak geçtiğimiz son yıllarda büyük bir artış göstermişlerdir. İki yıl önceki değerlendirmelere göre, dünya kolay bozulabilir gıda maddeleri üretiminin 1 milyar ton olduğu Anquez, M. 1975 ve bu miktarın dörtte birinin (250 milyon ton herhangi bir şekilde işlenmesinde soğuğun kullanıldığı kabul edilmektedir.

  13. Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking.

    Directory of Open Access Journals (Sweden)

    Anna E Daniel

    Full Text Available Plasminogen activator inhibitor-1 (PAI-1, a serine protease inhibitor, is expressed and secreted by endothelial cells. Patients with PAI-1 deficiency show a mild to moderate bleeding diathesis, which has been exclusively ascribed to the function of PAI-1 in down-regulating fibrinolysis. We tested the hypothesis that PAI-1 function plays a direct role in controlling vascular integrity and permeability by keeping endothelial cell-cell junctions intact.We utilized PAI-039, a specific small molecule inhibitor of PAI-1, to investigate the role of PAI-1 in protecting endothelial integrity. In vivo inhibition of PAI-1 resulted in vascular leakage from intersegmental vessels and in the hindbrain of zebrafish embryos. In addition PAI-1 inhibition in human umbilical vein endothelial cell (HUVEC monolayers leads to a marked decrease of transendothelial resistance and disrupted endothelial junctions. The total level of the endothelial junction regulator VE-cadherin was reduced, whereas surface VE-cadherin expression was unaltered. Moreover, PAI-1 inhibition reduced the shedding of VE-cadherin. Finally, we detected an accumulation of VE-cadherin at the Golgi apparatus.Our findings indicate that PAI-1 function is important for the maintenance of endothelial monolayer and vascular integrity by controlling VE-cadherin trafficking to and from the plasma membrane. Our data further suggest that therapies using PAI-1 antagonists like PAI-039 ought to be used with caution to avoid disruption of the vessel wall.

  14. FINDIK KABUKLARININ, ÇAY VE TÜTÜN ATIKLARININ HAMMADDE OLARAK KULLANILMASI

    Directory of Open Access Journals (Sweden)

    Ş. İsmail KIRBAŞLAR

    2001-01-01

    Full Text Available Bu çalışmada, fındık kabukları, çay ve tütün atıklarındaki nem, kül, yağ ve sellüloz miktarları analiz edilmiştir. Ayrıca, fındık kabukları, çay ve tütün atıklarının içerdiği pentosan, pentos ve furfural miktarları belirlenmiştir. Furfural her üç atıktan destilasyon metoduyla ayrılmıştır. Atıklardan ayrılan furfural örneklerinin IRspektrumları ile standart furfuralin IR-spektrumları karşılaştırılmıştır. Fındık kabuklarından farklı sıcaklıklarda aktif karbon elde edilmiştir. Bu aktif karbon kullanılarak organik ve anarganik atıklar adsorbsiyonla uzaklaştırılmıştır.

  15. Küreselleşme ve Yeni Uluslararası Ekonomik Düzen

    OpenAIRE

    GÜRKAN, ÖMER

    2001-01-01

    Son dönemlerin çok sık duyduğumuz sözcüklerinden biri “küreselleşme”, bazen ekonomik ilişkilerin yoğunlaşması, mal ve hizmetlerle emek ve sermayenin artan bir serbestlikle tüm dünyada dolaşması, bazen kültür, inanç ve ideallerin benzeşmesi olarak tanımlanmaktadır. Çok genel bir ifadeyle, küreselleşme, her tür değer ve birikimin ulusal sınırları aşarak dünya çapında yaygınlaşması şeklinde, tanımlanabilir. Ekonomik açıdan bakıldığında ise, küreselleşme, üretim, ticaret ve sermaye ile işgücü ha...

  16. KALİTELİ UYKU VE UYKU BOZUKLUKLARI / QUALITY SLEEP AND SLEEP DISORDERS

    OpenAIRE

    Algın, Demet; Akdağ, Gönül; Erdinç, Oğuz

    2018-01-01

    Özet: Uyku sağlık ve yaşamımızın iyi bir şekilde devamı için önemli bir role sahiptir. Kaliteli uyku zihinsel sağlığımızı, fiziksel sağlığımızı, hayat kalitemizı korumamıza yardım eder ve güvenliğimiz için gereklidir. Uykunun başlatılması ve sürdürülmesi kortikal ve subkortikal birçok beyin bölgesinin işlevi ile gerçekleşir. Uykunun başlatılmasında öncelikle ön hipotalamustan gelen döngüsel girdiler ve endojen kimyasal uyarılar doğrultusunda hipotalamusta ventrolateral preoptik çekirdeğin rol...

  17. BAĞDA SİLKME VE SİLKMEYE NEDEN OLAN FAKTÖRLER

    OpenAIRE

    BAHAR, ELMAN; KORKUTAL, İLKNUR; DOĞAN, AHU ZÜBEYDE

    2009-01-01

    Bağda görülen önemli problemlerden biri olan silkme üzerine birçok çalışma yapılmıştır. Bu derleme ile tür ve çeşitlerin fizyolojik ve genetik özellikleri, toprak koşulları, iklim, hastalık ve zararlılar ile yetersiz ve hatalı kültürel işlemler sonucu meydana gelen silkmenin nedenleri açıklanmaya çalışılmıştır. Bu kapsamda; fizyolojik kökenli silkme başlığı altında; asmanın gelişme kuvveti, kusurlu çiçek yapısı, yetersiz tozlanma ve döllenme üzerinde durulmuştur. İklim kökenli silkme ana başl...

  18. ELEKTRİKLİ EV ALETLERİNDE CE UYUMLULUĞU VE BİR UYGULAMA

    Directory of Open Access Journals (Sweden)

    Nazmi EKREN

    2009-01-01

    Full Text Available Hızla gelişen teknoloji, artan rekabet ortamı ve kullanıcının bilinçlenmesi gibi nedenlerden dolayı kaliteli üretim yapmanın gerekliliği günümüzde daha da artmıştır. Ürün kalitesinin ve güvenilirliğinin belgelenmesi tüketici açısından şart olmuştur. Ürün güvenliğinin belgelenmesinde kullanılan birçok belge vardır. Bu belgelerden biri de CE belgesidir. Bu makalede, CE işareti ile ilgili temel bilgi verilmiş ve elektrikli ev aletleri için gerekli CE standartları ve testlerinden bahsedilmiştir. Örnek olarak elektrikli ev aletlerinden tost makinesi ele alınmış, incelenmiştir. Tost makinesine CE belgesi almak için EN60335-2-9 direktifine göre gerekli testler yapılmış ve CE belgesi alınmıştır.

  19. 76 FR 14058 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... in the possession and control of the University of Wyoming Anthropology Department, Human Remains... made by University of Wyoming, Anthropology Department, Human Remains Repository, professional staff in...

  20. You’ve Got Email: a Workflow Management Extraction System

    NARCIS (Netherlands)

    P. Chaipornkaew (Piyanuch); T. Prexawanprasut (Takorn); M.J. McAleer (Michael)

    2017-01-01

    textabstractEmail is one of the most powerful tools for communication. Many businesses use email as the main channel for communication, so it is possible that substantial data are included in email content. In order to help businesses grow faster, a workflow management system may be required. The

  1. Zenginleştirilmiş Ekmeklerde İşleme ve Depolama Sırasında Bazı Vitamin ve Mineral Madde Miktarlarındaki Değişmeler

    Directory of Open Access Journals (Sweden)

    Mehmet Karagül

    2015-02-01

    Full Text Available Bu çalışmada farklı konsantrasyonlarda tiyamin (7.5, 15.0 ve 22.5 mg/kg, riboflavin (7.5, 15.0 ve 22.5 mg/kg, demir (10, 20 ve 30 mg/100 g, magnezyum (50, 75 ve 100 mg/100 ve kalsiyum (200, 300 ve 400 mg/100 g katılanlardan yapılan hamurlarda ve ekmeklerde besin öğelerinin kalma oranı araştırılmıştır. Ekmek pişirmede uygulanan sıcaklık 250 oC ve süre 25 dakikadır. Un tipi ve katkı konsantrasyonu tiyamin, demir ve kalsiyumun ekmekte kalma oranı üzerinde etkili olmuş, riboflavin ve magnezyumu etkilememiştir. Araştırma sonuçlarına göre; una kıyasla hamurda kalma oranı demir için %89.75-107.54, magnezyum için %97.69-106.00, kalsiyum için %99.59-123.67, tiyamin için %42.34-99.59 ve riboflavin için %86.49-97.46’dır. Una göre ekmekte (72 saat sonra kalma oranı ise demir için %76.21-81.97, magnezyum için %74.54-90.03, kalsiyum için %77.56-95.16, tiyamin için %27.82-58.75 ve riboflavin için %59.78-83.78’dir. Demir, kalsiyum ve magnezyumun katkı konsantrasyonu arttıkça ekmek hacmi azalmış, ekmek içi ve aroması bozulmuştur.

  2. GPR investigation to allocate the archaeological remains in Mut temple, Luxor, Upper Egypt

    Directory of Open Access Journals (Sweden)

    M.A. Atya

    2012-06-01

    Full Text Available GPR investigation has been conducted on Mut temple; to the south portion of Al-Karnak temple at the eastern bank of Luxor city. Within the survey, the GPR SIR system-10A has been used connected to 100/500 MHz antenna. The present work is oriented to allocate the buried Archaeological ruins at the site, and also to evaluate the archaeological significance of the artifacts in concern to the hydro-situation. The survey is composed of three data sets; the first set (A includes three GPR profiles located inside the temple palisade at the western bank of the holy lake, the second set (B includes four profiles distributed on the yard between Mute and Al Karnak temples, and the third set (C includes three profiles oriented to study the EW Sphinx Avenue front of Mute temple. The measured GPR data has been processed and visualized in different ways to show the infra-content of the artifacts in the buried subsurface of the temple. Furthermore, intensive mutual work and discussion with the local inspectorate at Luxor about the results would lead to detect the zones of possible findings and, as much as possible, to define their identities. A series of sectional GPR records, time slices, maps, and 3D graphs are introduced to represent the remains of Mut temple and its infrastructure.

  3. The Associations between Yelp Online Reviews and Vape Shops Closing or Remaining Open One Year Later.

    Science.gov (United States)

    Kong, Grace; Unger, Jennifer; Baezconde-Garbanati, Lourdes; Sussman, Steve

    2017-01-01

    Vape shops are popular brick-and-mortar stores that sell e-cigarette products but are not understood well. Previous analysis of Yelp reviews of vape shops located in various ethnic neighborhoods in Los Angeles, California in 2014 identified characteristics of vape shop as delineated by consumers. In this study, we assessed the associations between these characteristics and vape shops going out of business in 2015. Content analysis of Yelp reviews of 72 vape shops in 2014 identified 1) general characteristics of the reviews/reviewers, 2) vape shop, staff, and marketing attributes, 3) physical environment, and 4) health claims. In 2015, in-person visits confirmed that 22% of these vape shops closed permanently. We analyzed whether characteristics/attributes identified in 2014 associated with stores remaining open (n = 56) or permanently closing (n = 16) in 2015. Univariate findings showed that open vape shops relative to closed shops had greater 1) number of reviews, 2) rebuilds/fixings, 3) ratings of staff attributes as "helpful/patient/respectful," and 4) report of the physical environment as "bar type." Bar type vape shops and those with rebuilding/fixing capabilities were associated with staying open, suggesting the popularity of these attributes. Yelp consumer reviews is a useful research tool to identify consumer-determined important sustaining attributes of vape shops and may be used to identify aspects of enduring shops that need regulations.

  4. The Associations between Yelp Online Reviews and Vape Shops Closing or Remaining Open One Year Later

    Science.gov (United States)

    Kong, Grace; Unger, Jennifer; Baezconde-Garbanati, Lourdes; Sussman, Steve

    2017-01-01

    INTRODUCTION Vape shops are popular brick-and-mortar stores that sell e-cigarette products but are not understood well. Previous analysis of Yelp reviews of vape shops located in various ethnic neighborhoods in Los Angeles, California in 2014 identified characteristics of vape shop as delineated by consumers. In this study, we assessed the associations between these characteristics and vape shops going out of business in 2015. METHODS Content analysis of Yelp reviews of 72 vape shops in 2014 identified 1) general characteristics of the reviews/reviewers, 2) vape shop, staff, and marketing attributes, 3) physical environment, and 4) health claims. In 2015, in-person visits confirmed that 22% of these vape shops closed permanently. We analyzed whether characteristics/attributes identified in 2014 associated with stores remaining open (n = 56) or permanently closing (n = 16) in 2015. RESULTS Univariate findings showed that open vape shops relative to closed shops had greater 1) number of reviews, 2) rebuilds/fixings, 3) ratings of staff attributes as “helpful/patient/respectful,” and 4) report of the physical environment as “bar type.” CONCLUSIONS Bar type vape shops and those with rebuilding/fixing capabilities were associated with staying open, suggesting the popularity of these attributes. Yelp consumer reviews is a useful research tool to identify consumer-determined important sustaining attributes of vape shops and may be used to identify aspects of enduring shops that need regulations. PMID:29057379

  5. Microscopic Void Detection for Predicting Remaining Life in Electric Cable Insulation

    International Nuclear Information System (INIS)

    Horvath, David A.; Avila, Steven M.

    2003-01-01

    A reliable method of testing for remaining life in electric cable insulation has continued to elude the nuclear industry as it seeks to extend the life and license of its nuclear stations. Until recently, a trendable, measurable electrical property has not been found, and unexpected cable failures continue to be reported. Most reliable approaches to date rely on monitoring mechanical properties, which are assumed to degrade faster than the insulation's electrical properties. This paper introduces a promising technique based on void characterization, which is dependent on an electrical property related to dielectric strength. A relationship between insulation void characteristics (size and density) and the onset of partial discharge is known to exist. A similar relationship can be shown between void characteristics and unacceptable leakage currents (another typical cable failure criterion). For low-voltage cables, it is believed void content can be correlated to mechanical property degradation.This paper will report on an approach for using void information, research results showing the existence of trendable void characteristics in commonly used electric insulation materials, and techniques for detecting the voids (both laboratory- and field-based techniques). Acoustical microscopy was found to be potentially more suitable than conventional ultrasound for nondestructive in situ detection and monitoring of void characteristics in jacketed multiconductor insulation while ignoring the jacket. Also, optical and scanning electron microscope techniques will play an essential role in establishing the database necessary for continued development and implementation of this promising technique

  6. Human cultural and related remains from Me Aure Cave (site WMD007), Moindou, New Caledonia

    International Nuclear Information System (INIS)

    Grant-Mackie, J.A.; Sand, C.; Valentin, F.; Fitzgerald, B.M.; Richer de Forges, B.

    2013-01-01

    In 1995 a small cave near Me Aure (site WMD007) on the west coast of New Caledonia, about 120 km northwest of Noumea, was excavated and found to contain mainly owl and human midden deposits. Some of the contents have already been documented and the present paper completes the study by reporting the human-related materials, including human bone fragments, pottery sherds, bones of four rodent species, and marine mollusc and crab remains. Each of these material classes are reported separately by the authors responsible for their analysis, and the results and interpretations based on each line of evidence are compared and contrasted. The human bone and pottery data suggest a temporally constrained deposit (2750-2350 BP) that has experienced stratigraphic disturbance. This result raises doubt about the un-mixed nature of the deposit emphasized in earlier publications and it urges instead the conclusion that the Me Aure stratigraphy consists mostly of a redeposited set of horizons. If this conclusion is correct, interpretations already published relying on a fixed chronology, especially about vegetation change and avifauna depletion or early aroid introduction will need to be reconsidered. The site constitutes the first in New Caledonia for which a cave deposit has now been fully analysed. (author). 36 refs., 11 figs., 9 tabs.

  7. Sanayi 4.0 ve Türkiye Ekonomisi Açısından Etkileri

    OpenAIRE

    AYDEMİR, Halit

    2018-01-01

    Bu çalışmada Sanayi 4.0’ın küresel dünya ekonomisi ve Türkiye ekonomisi üzerindeki etkileri, avantaj ve dezavantajları, Sanayi 4.0’ın diğer devrimlerle olan bağı ele alınmaktadır. Bu çerçevede Türkiye için Sanayi 4.0 gelişim sürecinde izlenmesi gereken bir yol haritasının çizilmesi amaçlanmıştır. Yöntemsel olarak ülkeler ve yıllar arası karşılaştırmalı analizler kullanılmıştır.

  8. FItness programy a individuální přístup ve fitness

    OpenAIRE

    Rambous, Milan

    2008-01-01

    Souhrn: Tato diplomová práce se zabývá problematikou fitness programů a individuálru'ho přístupu ve fitness centrech. Celé téma zahrnuje rozpracování postupu při vytváření fitness programů a roli osobního trenéra ve fitness. Dále jsou zde uvedeny specifika některých fitness programů a v empirické části pak příklad dvou individuálních fitness programů. Název práce: Fitness programy a individuálnípřístup ve fitness Title: FITNESS PROGRAMS AND INDIVIDUAL CARE IN FITNESS Cíle práce: 1. podrobný p...

  9. Müşteri İlişkileri ve CRM = Customer Care & Social CRM

    OpenAIRE

    Yaşar, Azra Betül

    2016-01-01

    Azra Betül Yaşar şu anda Turkcell'de çalışmaktadır ve müşteri ilişkileri yönetimi alanında uzman olarak hizmet vermektedir. Mart 2011'den beri bu görevi yürüten Yaşar; proje yönetimi, stratejik planlama, bilgi yönetimi, sosyal medya, bütçe yönetimi, ve data analizi konularında deneyim kazanmış birisidir. Müşterilerin Turkcell ile en iyi şekilde iletişimde kalmasını sağlamak, ve Turkcell deneyimlerini her zaman en yukarda tutmak için çalışmaktadır. Doğu Akdeniz Üniversitesi (DAÜ) Sosyal Med...

  10. Yatarak fizyoterapi alan hastaların yaşam kaliteleri ve maliyet analizi

    OpenAIRE

    AKTAŞ, İlknur; KAPTANOĞLU YILDIRIM, Ayşegül; ÜNLÜ ÖZKAN, Feyza; YILMAZ KAYSIN, Meryem; ŞİLTE, Ayşe Duygu

    2015-01-01

    Amaç: Lokomotor sistem sorunları nedeniyle yatarak fizyoterapi alan hastaların yaşam kaliteleri ve maliyet analizlerini ortaya koymaktır. Hastalar ve Yöntem: Yatarak fizyoterapi alan olguların demografik verileri kaydedildi ve 15 D yaşam kalite sorgulaması yapıldı. Maliyetleri hesaplandı. Yaşam kalitesi ölçeği verilerini kullanarak hesaplanan, kaliteye ayarlanmış yaşam yılı (KAYY) sayısını kullanarak ekonomik analiz yapılmıştır. Bulgular: Doksan üç olgunun 75’i (%80,64) kadın, 18’i (%19,35) e...

  11. Radurizasyonun Tavuk Etlerinin Duyusal, Kimyasal ve Mikrobiyolojik Kalitesi Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Nuray Kolsarıcı

    2015-02-01

    Full Text Available Araştırmada 1, 2 ve 3 kGy dozunda uygulanan iyonize radyasyonun (Radurizasyon tavuk but ve göğüs etlerinin mikrobiyolojik, kimyasal ve duyusal kalitelerine olan etkisi üzerinde çalışılmıştır. 6-8 haftalık broilerler kesilerek but ve göğüs etlerine parçalandıktan sonra biri açık kontrol olmak üzere 5 gruba ayrılmış ve 4 grup vakum paketlenmiştir. Vakum paketi gruplardan biri vakumlu kontrol olarak ayrılırken, diğer gruplar 1, 2 ve 3 kGy olmak üzere iyonize radyasyona tabi tutulmuştur. 0. günden başlamak üzere 3’er günlük periyotlarla gruplar analize alınmış, toplam mezofilik aerob, toplam psikrofilik aerob, stafilokok ve laktik asit bakterileri ile pH ve TBA değeri belirlenmiştir. Ayrıca örneklerin duyusal özellikleri de panel oluşturularak saptanmıştır. Elde edilen tüm veriler varyans analizi ile değerlendirilmiştir. Araştırma bulgularına göre tavuk but ve göğüs etlerinde radurizasyon sonrası bakteriyel yükte azalma gözlenmiştir. Radurizasyonun toplam mezofilik aerobik ve toplam psikrofilik aerobik bakteriler üzerine olan etkisi stafilokok ve laktik asit bakterilerine kıyasla daha yüksek düzeyde olup, özellikle laktik asit bakterilerinde zayıf kalmıştır. PH ve TBA değerleri açısından radurizasyonun değişiklik yaratmadığı gözlenmiştir. Bununla birlikte 3 kGy ışınlanmış örneklerin raf ömrü 27 gün civarında olurken 2 kGy ışınlı örnekler 24 günde, 1 kGy ışınlı örnekler 18 günde, vakumlu kontroller 15 günde, açık kontroller 9 gün civarında tüketim özelliğini yitirmiştir. Duyusal değerlendirmelerde alınan sonuçlarda ışınlanmış örneklerin renk, görünüş, aroma, gevreklik gibi özellikleri kontrollere göre farklı olmayıp, tüm gruplar pazarlanabilir nitelikte bulunmuşlardır.

  12. FEKAL İNKONTİNANSIN BAKIMI VE BAKIMDA KULLANILAN ÜRÜNLER

    OpenAIRE

    Denat, Yıldız; Khorshid, Leyla

    2010-01-01

    ÖZETFekal inkontinans, özellikle uzun dönem yatağa bağımlı hastalarda kontaminasyonaçısından güç sonuçlarla, enfeksiyon ve deri ülserlerinin oluşma riskiyle, pahalı ve potansiyeltehlikelere neden olan bir durumdur. Fekal inkontinans, normal deri bütünlüğü için potansiyel birtehlike yaratır ve septiseminin bir nedeni olabilir. Özellikle yatağa bağımlı fekal inkontinanslıhastalar perineal deri hasarı için risk ...

  13. Siber Saldırılar Siber Savaşlar ve Etkileri

    OpenAIRE

    Kara, Mahruze

    2013-01-01

    74 pages. İnternetin ortaya çıkması ile yararlarından faydalanılmaktadır. Ancak internetin zararları da mevcuttur. İnternet, dünya dengelerini değiştirmektedir. İnternet, siber saldırılara ve siber savaşlara aracılık eden bir alan olmuştur. Siber saldırılar, ülkelerin ulusal ve ekonomik güvenliğini sarsmaktadır. Siber savaşlar 5. boyutta yapılmaktadır. Bu çalışmada siber silahlar ile siber saldırılar ve siber savaşların etkileri işlenmiştir. Siber güvenlik önlemleri için çöz...

  14. Mersin (Myrtus communis L. Meyvesinin bazı Fiziksel ve Kimyasal Özellikleri

    Directory of Open Access Journals (Sweden)

    Musa Özcan

    2015-02-01

    Full Text Available İçel’den (Büyükeceli-Gülnar toplanan farklı büyüklük ve renklerdeki mersin (Myrtus communis L. meyvelerinin fiziksel ve kimyasal özellikleri belirlenmiştir. Mor meyvelerde antosiyanin tespit edilirken beyaz renklide bulunmamıştır. Mor meyvelerde tanen miktarı beyazlara göre oldukça yüksektir. Titrasyon asitliği mor meyvelerde aynı olup, beyaza göre yüksektir. Meyveler mineral bakımından zengindir ve en yüksek olarak potasyum belirlenmiştir.

  15. Mersin (Myrtus communis L.) Meyvesinin bazı Fiziksel ve Kimyasal Özellikleri

    OpenAIRE

    Özcan, Musa; Akbulut, Mehmet

    1998-01-01

    İçel’den (Büyükeceli-Gülnar) toplanan farklı büyüklük ve renklerdeki mersin (Myrtus communis L.) meyvelerinin fiziksel ve kimyasal özellikleri belirlenmiştir. Mor meyvelerde antosiyanin tespit edilirken beyaz renklide bulunmamıştır. Mor meyvelerde tanen miktarı beyazlara göre oldukça yüksektir. Titrasyon asitliği mor meyvelerde aynı olup, beyaza göre yüksektir. Meyveler mineral bakımından zengindir ve en yüksek olarak potasyum belirlenmiştir. 

  16. Robotlar İşlerimizi ve Ruhumuzu mu Çalacak?

    OpenAIRE

    Yılmaz, Fevzi

    2018-01-01

    Robotlar, bazen insan formunda bazen ise daha mekanik-elektronik araçlar olarak ekonomik hayatın içindeler. Dijital çağdayız ve robotlar artık kendilerine verilen yetkinlikler sayesinde insanların yapabildiği şeyleri gerçekleştirebiliyor. Robotların işsizliğe yol açacağı ve ekonomik eşitsizliği derinleştireceği sık sık gündeme gelmektedir. Bilim kurgu dizi konusu olan öldüren robotlar ve robotun kendini yapandan daha akıllı robotu üretmesi savı hep endişe vermiştir. Ünlülerden Stephen Hawking...

  17. Elektrikli Otomobil, Küresel Rekabet ve Gelişmeler

    OpenAIRE

    Yılmaz, Fevzi

    2017-01-01

    Önceki Bilim, Sanayi ve Teknoloji Bakanı Fikri Işık Mayıs 2016'da verdiği beyanatta yerli otomobil projesiyle Google ve Tesla gibi devlerin rakibi olacağımızı belirtmişti. Bakan Işık o tarihte, “Tüm otomotiv devleri, işbirliği için sırada bekliyor. Sonuçta bizim de elimizde önemli teknolojiler var.” diyerek moral tazelemişti. Sözü edilen Google, araç otomasyonu ve sürücüsüz araç projesi yürütmekte iken, Tesla ise dünyanın en büyük farklı konsept elektrikli araç üreticisidir. Tesla'nın CEO’su ...

  18. Information Need and Information Seeking Behaviour Bilgi Gereksinimi ve Bilgi Arama Davranışı

    Directory of Open Access Journals (Sweden)

    Nazan Özenç Uçak

    1997-12-01

    Full Text Available Information need is one of the cognitive needs of humankind. Information need causes information seeking behaviour and these concepts complement each other. Information need and information seeking behaviour are effected by many factors. It is necessary to know these factors in establishing the effective information centers and services. Bilgi gereksinimi insanın zihinsel gereksinimlerinden birisidir. Bilgi gereksinimi sonuçta bilgi arama davranışını ortaya çıkarmakta ve bu iki kavram birbirini tamamlamaktadır. Bilgi gereksinimi ve bilgi arama davranışı pek çok faktörden etkilenmektedir. Etkili bilgi merkezlen ve hizmetleri kurabilmek için bu faktörlerin bilinmesi gerekmektedir.

  19. İRAN VE REJİM İSTİKRARI

    Directory of Open Access Journals (Sweden)

    Özgür ÜŞENMEZ

    2015-07-01

    Full Text Available ÖZ: Bu çalışma, İran rejiminin son yıllarda Orta Doğu'yu sarsan isyanlar ve istikrarsızlıklara-Batı'daki beklentilerin aksine- geçmişten, özellikle 1979'daki devrimden miras kalan sosyal yapı ve politikaların etkisiyle direnebildiğini iddia ediyor. Tunus ve Mısır'daki halk isyanları, temel aktör olan alt sınıflar ve onların neo-liberal ekonomik politikalara muhalefetiyle yayılırken, İran’da devrim sonrası gelişen sosyal devlet mekanizması hala halk ile rejimin tamamen birbirine yabancılaşmasını önlemekte. Ancak son yıllarda ortaya çıkan yeni gerilimler ve İran'ın uyguladığı ekonomi politikaları rejimin krizini derinleştirebilir. Bu nedenledir ki Orta Doğu'yu ve özelde İran'ı anlamak için hegemonik blokların tarihsel değişimini inceleyen ucu açık bir analiz elzemdir. ABSTRACT: This article argues that contrary to the expectations of the Western World, Iranian regime successfully resisted the revolutionary tides of the Arab Spring. Most important determinant of this process for Iran was the legacy of the 1979 revolution and it's associated structures that relatively protects the most vulnerable parts of the population against the wide spread neo-liberal economic policies in the Middle East. So with that feature Iran differs from the Tunisian and the Egyptian examples. In order to understand these features further this essay adapts a historical analysis of changes in hegemonic blocs in Iran since 1979.

  20. Qualitative Content Analysis

    OpenAIRE

    Philipp Mayring

    2000-01-01

    The article describes an approach of systematic, rule guided qualitative text analysis, which tries to preserve some methodological strengths of quantitative content analysis and widen them to a concept of qualitative procedure. First the development of content analysis is delineated and the basic principles are explained (units of analysis, step models, working with categories, validity and reliability). Then the central procedures of qualitative content analysis, inductive development of ca...

  1. Reduced γ-Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk

    Directory of Open Access Journals (Sweden)

    Junjie Wang

    2016-01-01

    Full Text Available Altered γ-aminobutyric acid (GABA, glutamate (Glu levels, and an imbalance between GABAergic and glutamatergic neurotransmissions have been involved in the pathophysiology of schizophrenia. However, it remains unclear how these abnormalities impact the onset and course of psychosis. In the present study, 21 drug-naïve subjects at ultrahigh risk for psychosis (UHR, 16 drug-naïve patients with first-episode schizophrenia (FES, and 23 healthy controls (HC were enrolled. In vivo GABA and glutamate+glutamine (Glx levels in the medial prefrontal cortex were measured using proton magnetic resonance spectroscopy. Medial prefrontal GABA and Glx levels in FES patients were significantly lower than those in HC and UHR, respectively. GABA and Glx levels in UHR were comparable with those in HC. In each group, there was a positive correlation between GABA and Glx levels. Reduced medial prefrontal GABA and Glx levels thus may play an important role in the early stages of schizophrenia.

  2. Reduced γ-Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk.

    Science.gov (United States)

    Wang, Junjie; Tang, Yingying; Zhang, Tianhong; Cui, Huiru; Xu, Lihua; Zeng, Botao; Li, Yu; Li, Gaiying; Li, Chunbo; Liu, Hui; Lu, Zheng; Zhang, Jianye; Wang, Jijun

    2016-01-01

    Altered γ -aminobutyric acid (GABA), glutamate (Glu) levels, and an imbalance between GABAergic and glutamatergic neurotransmissions have been involved in the pathophysiology of schizophrenia. However, it remains unclear how these abnormalities impact the onset and course of psychosis. In the present study, 21 drug-naïve subjects at ultrahigh risk for psychosis (UHR), 16 drug-naïve patients with first-episode schizophrenia (FES), and 23 healthy controls (HC) were enrolled. In vivo GABA and glutamate+glutamine (Glx) levels in the medial prefrontal cortex were measured using proton magnetic resonance spectroscopy. Medial prefrontal GABA and Glx levels in FES patients were significantly lower than those in HC and UHR, respectively. GABA and Glx levels in UHR were comparable with those in HC. In each group, there was a positive correlation between GABA and Glx levels. Reduced medial prefrontal GABA and Glx levels thus may play an important role in the early stages of schizophrenia.

  3. Identification of groups with poor cost-effectiveness of peginterferon plus ribavirin for naïve hepatitis C patients with a real-world cohort and database.

    Science.gov (United States)

    Tsai, Pei-Chien; Liu, Ta-Wei; Tsai, Yi-Shan; Ko, Yu-Min; Chen, Kuan-Yu; Lin, Ching-Chih; Huang, Ching-I; Liang, Po-Cheng; Lin, Yi-Hung; Hsieh, Ming-Yen; Hou, Nai-Jen; Huang, Chung-Feng; Yeh, Ming-Lun; Lin, Zu-Yau; Chen, Shinn-Cherng; Dai, Chia-Yen; Chuang, Wan-Long; Huang, Jee-Fu; Yu, Ming-Lung

    2017-06-01

    For decades, peginterferon and ribavirin (PegIFN/RBV) have been the standard-of-care for chronic hepatitis C virus (CHC) infection. However, the actual cost-effectiveness of this therapy remains unclear. We purposed to explore the real-world cost effectiveness for subgroups of treatment-naïve CHC patients with PegIFN/RBV therapy in a large real-world cohort using a whole population database. A total of 1809 treatment-naïve chronic hepatitis C virus (HCV) patients (829 HCV genotype 1 [G1] and 980 HCV G2) treated with PegIFN/RBV therapies were linked to the National Health Insurance Research Database, covering the entire population of Taiwan from 1998 to 2013 to collect the total medical-care expenses of outpatient (antiviral agents, nonantiviral agents, laboratory, and consultation costs) and inpatient (medication, logistic, laboratory, and intervention costs) visits. The costs per treatment and the cost per sustained virological response (SVR) achieved were calculated. The average medical-care cost was USD $4823 (±$2984) per treatment and $6105 (±$3778) per SVR achieved. With SVR rates of 68.6% and 87.8%, the cost/SVR was significantly higher in G1 than those in G2 patients, respectively ($8285 vs $4663, P incurred significantly higher costs per SVR than their counterparts. The cost/SVR was extremely high among patients without RVR and in patients without cEVR. We investigated the real-world cost effectiveness data for different subgroups of treatment-naïve HCV patients with PegIFN/RBV therapies, which could provide useful, informative evidence for making decisions regarding future therapeutic strategies comprising costly direct-acting antivirals.

  4. The natural history of surgically treated but radiotherapy-naïve nonfunctioning pituitary adenomas.

    LENUS (Irish Health Repository)

    O'Sullivan, Eoin P

    2009-11-01

    Transsphenoidal surgery is indicated for patients with nonfunctioning pituitary adenomas (NFPAs) causing compressive symptoms. Previous studies attempting to define the rate of recurrence\\/regrowth of surgically treated but radiation-naïve NFPAs were somewhat limited by selection bias and\\/or small numbers and\\/or lack of consistency of findings between studies. A better understanding of the natural history of this condition could allow stratification of recurrence risk and inform future management. We aimed to define the natural history of a large, mainly unselected cohort with surgically treated, radiotherapy (RT)-naïve NFPAs and to try to identify predictors of recurrence\\/regrowth.

  5. Van’da Tüketime Sunulan Feta Peynirlerinin Mikrobiyolojik ve Kimyasal Kalitesi

    Directory of Open Access Journals (Sweden)

    Enise Akel

    2016-11-01

    Full Text Available Bu çalışma, Van il merkezinde tüketime sunulan Feta peynirlerinin mikrobiyolojik ve kimyasal kalitesini belirlemek amacıyla yapıldı. Çalışmada 50 adet Feta peyniri materyal olarak kullanıldı. Feta peynirlerinin mikrobiyolojik analizleri sonucunda, ortalama olarak toplam aerob mezofil genel canlı sayısı 5,49 log kob/g, laktik asit bakteri sayısı 5,20 log kob/g, koliform grubu mikroorganizma sayısı 0,78 log kob/g, Escherichia coli sayısı 0,10 log kob/g, mikrokok/stafilokok sayısı 0,58 log kob/g, koagülaz pozitif Staphylococcus aureus sayısı 0,53 log kob/g, Clostridium perfringens sayısı 0,08 log kob/g, enterobakteri sayısı 0,96 log kob/g, maya ve küf sayısı ise 5,18 log kob/g olarak saptandı. Kimyasal analizler sonucunda ise ortalama pH değeri 4,38, titre edilebilir asitlik derecesi %1,41 LA, kuru madde miktarı %41,21, yağ miktarı %18,12, kuru maddede yağ miktarı %44,18, tuz miktarı %8,36 ve kuru maddede tuz miktarı %20,42 olarak tespit edildi. Feta peyniri örneklerinin tamamı titre edilebilir asitlik yönünden standartlara uygun bulundu. Ancak örneklerin %8’i koagülaz pozitif S. aureus, %52’si pH ve %100’ü kuru maddede tuz yönünden standartlara uygun bulunmadı. Sonuç olarak, Feta peynirlerinin mikrobiyolojik ve kimyasal kalitesinin yetersiz olduğu ve bu durumun üretici ve tüketiciler için risk oluşturabileceği kanısına varıldı. Gıda zincirinin tüm aşamalarında temeli GMP olan HACCP sisteminin uygulanması gıda güvenliği, halk sağlığı ve tüketici haklarının korunmasında etkin rol oynayacaktır.

  6. Veri Transferi Ve İşlem Güvenliğinin Sağlanmasında Kullanılan Şifreleme Yöntemleri Ve Sayısal İmza

    OpenAIRE

    ANBAR, Adem

    2004-01-01

    İnternetin ve e-ticaretin gelişmesi ve yaygınlaşması, güvenlik problemlerinin çözümüyle yakından ilişkilidir. Güvenlik sorununu; yetkilendirme, www (world wide web) güvenliği ve veri-işlem güvenliği olmak üzere üç açıdan inceleyebiliriz. Bu çalışmada, yetkilendirme ve www güvenliğine kısaca değinildikten sonra, veri-işlem güvenliği üzerinde ayrıntılı olarak durularak, veri işlem güvenliğinde kullanılan, kriptografi, onay kurumu, elektronik noter, elektronik ve sayısal imza gibi yeni güvenlik ...

  7. DOMATES DOKU VE KÜF KARAKTERİSTİKLERİ, DOMATES ÜRÜNLERİNDE KÜF SAYIMI VE KÜFÜ AZALTMA OLANAKLARI

    Directory of Open Access Journals (Sweden)

    Çetin KADAKAL

    2001-02-01

    Full Text Available Domates ve ürünlerinde en önemli kalite kriterlerinden biri, ürünün küf yüküdür. Domates ve ürünlerinde küf yükü; Howard küf sayım (HMC metoduna göre yapılmaktadır. Küf yükü, son ürünün hijyenik koşullarda üretilip üretilmediğini göstermesi açısından önemlidir. Küf yükünün maksimum sınırı ülkeden ülkeye değişmekle birlikte % 40-60 (pozitif alan arasındadır. Son yıllarda domates ve ürünlerinde ergosterol düzeyi küf yükü yerine yeni bir kriter olarak kabul edilmeye başlanmıştır.

  8. Menemen Ekolojik Koşullarında Lavanta (Lavandula spp.) Tür ve Çeşitlerinin Morfolojik, Verim ve Kalite Özelliklerinin Belirlenmesi

    OpenAIRE

    Karık, Ünal; Çiçek, Fatih; Çınar, Orçun

    2017-01-01

    Bu çalışma Menemen ekolojik koşullarında lavanta (Lavandula spp.) tür ve çeşitlerininmorfolojik, verim ve kalite özelliklerini belirlemek amacı ile 2015-2016yılları arasında yürütülmüştür. Çalışmada 2 farklı türe ait 8 farklı ticarilavanta çeşidi kullanılmıştır. 2 yıl sonucunda elde edilen veriler ışığında türve çeşitler arasında önemli farklılıklar bulunduğu tespit edilmiştir. Lavandintipi çeşitler, verim özellikleri açısından lavander tipi çeşitlerin önünegeçerken,  uçucu yağ oranı ve uçucu...

  9. Water content of aged aerosol

    Directory of Open Access Journals (Sweden)

    G. J. Engelhart

    2011-02-01

    Full Text Available The composition and physical properties of aged atmospheric aerosol were characterized at a remote sampling site on the northern coast of Crete, Greece during the Finokalia Aerosol Measurement Experiment in May 2008 (FAME-2008. A reduced Dry-Ambient Aerosol Size Spectrometer (DAASS was deployed to measure the aerosol water content and volumetric growth factor of fine particulate matter. The particles remained wet even at relative humidity (RH as low as 20%. The aerosol was acidic during most of the measurement campaign, which likely contributed to the water uptake at low RH. The water content observations were compared to the thermodynamic model E-AIM, neglecting any contribution of the organics to aerosol water content. There was good agreement between the water measurements and the model predictions. Adding the small amount of water associated with the organic aerosol based on monoterpene water absorption did not change the quality of the agreement. These results strongly suggest that the water uptake by aged organic aerosol is relatively small (a few percent of the total water for the conditions during FAME-08 and generally consistent with what has been observed in laboratory experiments. The water concentration measured by a Q-AMS was well correlated with the DAASS measurements and in good agreement with the predicted values for the RH of the Q-AMS inlet. This suggests that, at least for the conditions of the study, the Q-AMS can provide valuable information about the aerosol water concentrations if the sample is not dried.

  10. Sentiment analysis: a comparison of deep learning neural network algorithm with SVM and naϊve Bayes for Indonesian text

    Science.gov (United States)

    Calvin Frans Mariel, Wahyu; Mariyah, Siti; Pramana, Setia

    2018-03-01

    Deep learning is a new era of machine learning techniques that essentially imitate the structure and function of the human brain. It is a development of deeper Artificial Neural Network (ANN) that uses more than one hidden layer. Deep Learning Neural Network has a great ability on recognizing patterns from various data types such as picture, audio, text, and many more. In this paper, the authors tries to measure that algorithm’s ability by applying it into the text classification. The classification task herein is done by considering the content of sentiment in a text which is also called as sentiment analysis. By using several combinations of text preprocessing and feature extraction techniques, we aim to compare the precise modelling results of Deep Learning Neural Network with the other two commonly used algorithms, the Naϊve Bayes and Support Vector Machine (SVM). This algorithm comparison uses Indonesian text data with balanced and unbalanced sentiment composition. Based on the experimental simulation, Deep Learning Neural Network clearly outperforms the Naϊve Bayes and SVM and offers a better F-1 Score while for the best feature extraction technique which improves that modelling result is Bigram.

  11. Radioactive content in aerosols and rainwater

    International Nuclear Information System (INIS)

    Rodriguez Perestelo, N.; Lopez Perez, M.; Rodriguez, S.; Duarte, X.; Catalan, A.; Fernandez de Aldecoa, J. C.; Hernandez, J.

    2013-01-01

    The environmental radiological characterization of a place requires knowledge of the radioactive contents of its components, such as air (aerosol), rain, soil, etc ... Inhalation of radioactive aerosols in the air remains the main component of the total dose to the world population. This work focuses on its determination. (Author)

  12. VAROLUŞ FELSEFELERİ, VAROLUŞÇU TERAPİ VE SOSYAL HİZMET

    Directory of Open Access Journals (Sweden)

    Gizem ÇELİK

    2017-07-01

    Full Text Available Öz Varoluş felsefeleri, insanı ve insan yaşamını açıklamaya çalışan felsefi akımları temel alarak; ancak onlardan farklılaşan önemli nitelikleri ile günümüz insanının sorunlarına yönelen ve tek bir tanımlamayla anılması mümkün olmayan, kimilerine göre bir felsefe yapma tarzını kimilerine göre ise bir felsefi iklimi ifade etmektedir. En yalın ifadeyle, insanı nesne gibi ele alan ve yorumlayan yaklaşımlara tepki olarak, insanın biricik ve otantik oluşu özelliği ile tanımlanması gereken bir varoluş olduğunu belirten varoluşçu görüş, pek çok insanî soruyu ele alıp işleyerek “öz-varoluş ilişkisi”, “varlığın ve hayatın anlamı”, “özgür iradenin insan davranışlarındaki rolü”, “sınırsız özgürlük ve sorumluluk”, “varoluşsal anksiyete” gibi pek çok konuda açıklamalarda bulunmaktadır. Bu çalışmada, varoluş felsefelerine ve temel niteliklerine ilişkin genel bilgilere, artan ve karmaşıklaşan insan sorunlarının çözümünde önemli açıklamalar getirmesi dolayısıyla terapide yer bulan varoluşçu analizin özelliklerine ve odağı insan, insan sorun ve ihtiyaçları olan sosyal hizmet disiplin ve mesleğinin varoluş felsefeleri ile olan ilişkisine yer verilmektedir. Abstract Without a single definition, philosophies of existence sometimes described as the “way of making philosophy” or sometimes “climate of philosophy”. It basically arose from philosophical trends which are trying to explain human and life but differentiates from them by focusing on the problems of the modern man. By the simplest terms, existential philosophy states that human being must be defined as unique and authentic existent and it has born as a reaction to the approach that takes human beings as objects. Existential philosophy takes and examines many humanitarian questions such as "self-existence relationship”, “meaning of life and the existence”, “the role of

  13. Hydroponics: Content and Rationale

    Science.gov (United States)

    Ernst, Jeremy V.; Busby, Joe R.

    2009-01-01

    Technology education has the means of becoming the catalyst for integrated content and curricula, especially in core academic areas, such as science and mathematics, where it has been found difficult to incorporate other subject matter. Technology is diverse enough in nature that it can be addressed by a variety of content areas, serving as a true…

  14. Branded content infantil

    OpenAIRE

    Raúl RODRÍGUEZ-FERRÁNDIZ

    2017-01-01

    Reseña del libro Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes. Review of the book Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes.

  15. Branded content infantil

    Directory of Open Access Journals (Sweden)

    Raúl RODRÍGUEZ-FERRÁNDIZ

    2017-01-01

    Full Text Available Reseña del libro Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes. Review of the book Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes.

  16. Print advertising: vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.; Fransen, M.L.

    2012-01-01

    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  17. Print advertising : Vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.H.H.J.; Fransen, M.L.

    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  18. Qualitative Content Analysis

    OpenAIRE

    Satu Elo; Maria Kääriäinen; Outi Kanste; Tarja Pölkki; Kati Utriainen; Helvi Kyngäs

    2014-01-01

    Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studie...

  19. Social video content delivery

    CERN Document Server

    Wang, Zhi; Zhu, Wenwu

    2016-01-01

    This brief presents new architecture and strategies for distribution of social video content. A primary framework for socially-aware video delivery and a thorough overview of the possible approaches is provided. The book identifies the unique characteristics of socially-aware video access and social content propagation, revealing the design and integration of individual modules that are aimed at enhancing user experience in the social network context. The change in video content generation, propagation, and consumption for online social networks, has significantly challenged the traditional video delivery paradigm. Given the massive amount of user-generated content shared in online social networks, users are now engaged as active participants in the social ecosystem rather than as passive receivers of media content. This revolution is being driven further by the deep penetration of 3G/4G wireless networks and smart mobile devices that are seamlessly integrated with online social networking and media-sharing s...

  20. Kefir ve Kefir Kullanılarak Yapılan Bazı Ürünler

    OpenAIRE

    ESMEK, Emel; GÜZELER, Nuray

    2018-01-01

    Kefir, bakteri ve mayaların etkileriyle kefir daneleri içinde simbiyotik birleşmesi ile oluşan fermente bir süt ürünüdür. Kefir, ağızda hissedilen köpürücü etkisi, tipik maya tadı ve kendisine has belirli aromaları ile bilinir. Kefir fermentasyonun ana ürünleri içeceğin vizkozitesini, asitliğini ve düşük alkol içeriğini gösteren laktik asit, etanol ve karbondioksittir. İkincil bileşenler ise aroma kompozisyonuna katkıda bulunan, diasetil, asetaldehit, etil alkol ve aminoasittir. Kefir, vücudu...

  1. KARAGÖZ VE HACİVAT: BAŞKALDIRI VE İTAATİN YANSIMALARI / KARAGÖZ AND HACİVAT: PROJECTIONS OF SUBVERSION AND CONFORMANCE

    Directory of Open Access Journals (Sweden)

    ONUR AYKAÇ

    2016-12-01

    Full Text Available Bu yazı, James Smith’in Asian Theatre Journal’da 2004 yılında yayımladığı “Karagöz and Hacivat: Projections of Subversion and Conformance” adlı makalesinin tercümesidir. Smith, İslam dünyasında tiyatro temsillerinin tarihini kısaca anlattıktan sonra, sözü Türklerde karagöz, Yunanlarda karagiozis adıyla bilinen gölge oyunlarına getirir. Bu oyunlara dair kısa tanıtıcı bilgiler verdikten sonra, Peter Burke’ün Popular Culture in Early Modern Europe (Erken Modern Avrupa’da Popüler Kültür adlı eserinde hemen her karnavalda görüldüğünü söylediği “yemek, cinsellik ve şiddet” unsurlarına karagöz oyunlarından örnekler verir. Akabinde, gölge oyununu Mikhail Bakhtin’in dinsel eğlence teorisi çerçevesinde inceler. Bilhassa, sözü edilen teoride yer alan “bir maskaraya taç giydirilip kral yapılması ve karnavalın sonunda sahte kralın tahttan indirilmesi hadisesi” ile “Hacivat tarafından önemli bir mevkie getirildikten sonra çevresindekileri alt etmeye çalışan ve sonunda bütün gücü elinden alınan Karagöz’ün durumu” arasında ciddi bir benzerlik olduğu kanısına varır. Son aşamada, gölge oyununun, ezilen toplum kitlesinin özkimliğini yeniden oluşturmadaki rolüne değinerek, meseleyi Türk ve Yunan halkları üzerinden örneklendirir. Bu yazı, hem Batılı eğlence kuramlarının karagöz ve karagiozis oyunlarına uygulanmış olması, hem de bu oyunların yeni bir özkimlik oluşturmada nasıl bir görev üstlendiğini göstermesi bakımından önemlidir.

  2. The expression of VE-cadherin in breast cancer cells modulates cell dynamics as a function of tumor differentiation and promotes tumor-endothelial cell interactions.

    Science.gov (United States)

    Rezaei, Maryam; Cao, Jiahui; Friedrich, Katrin; Kemper, Björn; Brendel, Oliver; Grosser, Marianne; Adrian, Manuela; Baretton, Gustavo; Breier, Georg; Schnittler, Hans-Joachim

    2018-01-01

    The cadherin switch has profound consequences on cancer invasion and metastasis. The endothelial-specific vascular endothelial cadherin (VE-cadherin) has been demonstrated in diverse cancer types including breast cancer and is supposed to modulate tumor progression and metastasis, but underlying mechanisms need to be better understood. First, we evaluated VE-cadherin expression by tissue microarray in 392 cases of breast cancer tumors and found a diverse expression and distribution of VE-cadherin. Experimental expression of fluorescence-tagged VE-cadherin (VE-EGFP) in undifferentiated, fibroblastoid and E-cadherin-negative MDA-231 (MDA-VE-EGFP) as well as in differentiated E-cadherin-positive MCF-7 human breast cancer cell lines (MCF-VE-EGFP), respectively, displayed differentiation-dependent functional differences. VE-EGFP expression reversed the fibroblastoid MDA-231 cells to an epithelial-like phenotype accompanied by increased β-catenin expression, actin and vimentin remodeling, increased cell spreading and barrier function and a reduced migration ability due to formation of VE-cadherin-mediated cell junctions. The effects were largely absent in both MDA-VE-EGFP and in control MCF-EGFP cell lines. However, MCF-7 cells displayed a VE-cadherin-independent planar cell polarity and directed cell migration that both developed in MDA-231 only after VE-EGFP expression. Furthermore, VE-cadherin expression had no effect on tumor cell proliferation in monocultures while co-culturing with endothelial cells enhanced tumor cell proliferation due to integration of the tumor cells into monolayer where they form VE-cadherin-mediated cell contacts with the endothelium. We propose an interactive VE-cadherin-based crosstalk that might activate proliferation-promoting signals. Together, our study shows a VE-cadherin-mediated cell dynamics and an endothelial-dependent proliferation in a differentiation-dependent manner.

  3. Hamburgerlerin bazı Fiziksel, Kimyasal ve Mikrobiyolojik Özelliklerine Donmuş Depolama Sıcaklığı ve Depolama Süresinin Etkisi Üzerinde Araştırma

    Directory of Open Access Journals (Sweden)

    A. Hamdi Ertaş

    2015-02-01

    Full Text Available Ticari amaçla üretilen hamburgerler, -8 oC ve –26 oC’de 85 gün süre ile depolanmışlar ve depolama sıcaklığının ve süresinin hamburgerlerin bazı fiziksel, kimyasal ve mikrobiyolojik özellikleri üzerine olan etkileri araştırılmıştır. Fiziksel kriterler olarak su tutma kapasitesi (STK, pişirme kaybı (PK ve büzülme derecesi (BD; kimyasal kriterler olarak rutubet, protein, yağ miktarları ile pH değeri ve tiyobarbütirik asit (TBA sayısı; mikrobiyolojik kriterler olarak ise toplam mezofil aerob bakteri (TMAB sayısı, psikrofil bakteri (PB sayısı ve koliform grubu bakteri (KGB sayısı dikkate alınmıştır. Depolama sıcaklığı ve depolama süresinin rutubet, protein, yağ miktarları, STK, PK ve BD üzerine etkisinin olmadığı, pH değeri üzerine p<0.01 düzeyinde etkisinin olduğu, TBA-sayısı üzerine depolama sıcaklığının p<0.01 düzeyinde depolama süresinin p<0.05 düzeyinde etkisi olduğu belirlenmiştir. –8 oC de depolama, hamburgerlerin pH değerlerini ve TBA-sayılarını önemli düzeyde artırırken, -26 oC de depolamada artış daha az düzeyde olmuştur. TMAB, PB ve KGB sayılarına, depolama sıcaklığının ve depolama süresinin etkisi görülmüş (p<0.01; -8 oC’de, depolama süresine bağlı olarak TMAB, PB ve KGB sayılarında sürekli bir artış görülürken –26 oC’de depolamada azalma olmuştur.

  4. ETANOL + 1-NONANOL İKİLİ SİSTEMİ VE ETANOL + 1-NONANOL + SU ÜÇLÜ SİSTEMİNİN 293.15 K SICAKLIKTAKİ YOĞUNLUKLARININ, REFRAKTİF İNDİSLERİN ÖLÇÜLMESİ VE AŞIRI MOLAR HACİMLERİNİN VE MOLAR REFRAKSİYONLARININ HESAPLANMASI

    OpenAIRE

    MAHRAMANLIOĞLU, Mehmet; KIRBAŞLAR, Ş. İsmail

    2000-01-01

    Etanol+1-nonanol ikili sistemi ve etanol+1-nonanol+su üçlü sistemi için çeşitli karışımlarda yoğunluklar ve kırılma indisleri 293.15 K de ölçülmüştür. İkili ve üçlü sistemler için aşırı molar hacim ve molar refraksiyon sapmaları hesaplanmıştır. Aşırı molar hacim ve molar refraksiyon sapmaları için Redlich–Kister eşitliği uygulanarak eşitlik katsayıları hesaplanmıştır.

  5. VeA of Aspergillus niger increases spore dispersing capacity by impacting conidiophore architecture

    NARCIS (Netherlands)

    Wang, Fengfeng; Dijksterhuis, Jan; Wyatt, Timon; Wösten, Han A B; Bleichrodt, Robert-Jan

    Aspergillus species are highly abundant fungi worldwide. Their conidia are among the most dominant fungal spores in the air. Conidia are formed in chains on the vesicle of the asexual reproductive structure called the conidiophore. Here, it is shown that the velvet protein VeA of Aspergillus niger

  6. TÜRKİYE’DE BASEL I, II ve III KURALLARINA UYUM SÜRECİ

    OpenAIRE

    Ezgi ASLAN KÜLAHİ; Göksel TİRYAKİ; Ahmet YILMAZ

    2013-01-01

    TÜRKİYE’DE BASEL I, I VE III KURALLARINA UYUM SÜRECİÖzet: Bu çalışma, Basel Kriterleri çerçevesinde Türk Bankacılık Sektörü’nde yapılan çalışmaları değerlendirerek sektörün Basel Kriterleri’ne uyum sürecinde hangi aşamada olduğunu incelemek amacıyla yapılmıştır. Çalışmada; Türkiye’de Basel I ve II Kriterleri’ne geçiş süreci: Basel I ve II’ye yönelik yapılan hazırlık çalışmaları , Basel Kriterleri’ne uyum kapsamında Türk Bankacılık Mevzuatı’nda yapılan yasal düzenlemeler ve BDDK tarafından ger...

  7. First-Year Medical Students' Naïve Beliefs about Respiratory Physiology

    Science.gov (United States)

    Badenhorst, Elmi; Mamede, Silvia; Abrahams, Amaal; Bugarith, Kishor; Friedling, Jacqui; Gunston, Geney; Kelly-Laubscher, Roisin; Schmidt, Henk G.

    2016-01-01

    The present study explored the nature and frequency of physiology naïve beliefs by investigating novices' understanding of the respiratory system. Previous studies have shown considerable misconceptions related to physiology but focused mostly on specific physiological processes of normal respiration. Little is known about novices' broader…

  8. Measuring epistemological beliefs in history education : An exploration of naïve and nuanced beliefs

    NARCIS (Netherlands)

    Stoel, G.; Logtenberg, A.; Wansink, B.; Huijgen, T.; van Boxtel, C.; van Drie, J.

    2017-01-01

    This study investigates a questionnaire that measures epistemological beliefs in history. Participants were 922 exam students. A basic division between naïve and nuanced ideas underpins the questionnaire. However, results show this division oversimplifies the underlying structure. Exploratory factor

  9. Induced pluripotent stem cells derived from rabbits exhibit some characteristics of naïve pluripotency

    Directory of Open Access Journals (Sweden)

    Pierre Osteil

    2013-05-01

    Not much is known about the molecular and functional features of pluripotent stem cells (PSCs in rabbits. To address this, we derived and characterized 2 types of rabbit PSCs from the same breed of New Zealand White rabbits: 4 lines of embryonic stem cells (rbESCs, and 3 lines of induced PSCs (rbiPSCs that were obtained by reprogramming adult skin fibroblasts. All cell lines required fibroblast growth factor 2 for their growth and proliferation. All rbESC lines showed molecular and functional properties typically associated with primed pluripotency. The cell cycle of rbESCs had a prolonged G1 phase and a DNA damage checkpoint before entry into the S phase, which are the 2 features typically associated with the somatic cell cycle. In contrast, the rbiPSC lines exhibited some characteristics of naïve pluripotency, including resistance to single-cell dissociation by trypsin, robust activity of the distal enhancer of the mouse Oct4 gene, and expression of naïve pluripotency-specific genes, as defined in rodents. According to gene expression profiles, rbiPSCs were closer to the rabbit inner cell mass (ICM than rbESCs. Furthermore, rbiPSCs were capable of colonizing the ICM after aggregation with morulas. Therefore, we propose that rbiPSCs self-renew in an intermediate state between naïve and primed pluripotency, which represents a key step toward the generation of bona fide naïve PSC lines in rabbits.

  10. Gri Suyun Arıtımı ve Yeniden Kullanımı

    OpenAIRE

    ÜSTÜN, Gökhan; TIRPANCI, Ayşenur

    2015-01-01

    Çalışmanın amacı, gri su arıtımının ve yeniden kullanılması konusunun incelenmesidir. Bu amaç için daha önce yapılmış literatür çalışmaları araştırılıp, yorumlanmıştır. Çalışmanın ilk aşamasında gri suyun tanımlanması ile fiziksel, kimyasal ve biyolojik karakteristiği açıklanmıştır. İkinci kısmında, gri suyun arıtım yöntemleri ve yeniden kullanımı incelenmiştir. Üçüncü kısımda gri suların arıtımında kullanılan teknolojiler tek tek açıklanmıştır. Son olarak gri su arıtımı ve yeniden kullanımı ...

  11. Retrofit solutions for inland ships : The MoVe IT! approach

    NARCIS (Netherlands)

    Hekkenberg, R.G.; Thill, C.

    2014-01-01

    In MoVe IT!, a project in the European 7th framework package, it is investigated how existing European inland cargo ships can be retrofitted in order to improve their economic and environmental performance. In the project, experts from academia worked closely together with five ship owners to

  12. Ensemble/Variational Estimation (EnVE) and its application to canonical turbulent flow realizations

    Science.gov (United States)

    Colburn, Christopher; Cessna, Joseph; Bewley, Thomas

    2008-11-01

    The recently-developed hybrid EnVE method for data assimilation incorporates successive adjoint optimizations to update the initial conditions of a flow model, over various horizons of interest, in order to reconcile this model with recent measurements. Such adjoint optimizations typically require the trajectory to be saved over the entire interval over which the optimization is performed; in high-dimensional systems, this can lead to significant storage problems, which can be partially alleviated via checkpointing. In the EnVE framework, this requirement is eliminated, and supplanted by a requirement to march the state of the system backward in time simultaneously with the adjoint. If the system is derived from a PDE with a diffusive component, this backward-in-time state march is ill conditioned, and requires regularization/smoothing to prevent errors from accumulating rapidly at the small scales. The present talk focuses on this peculiar requirement of the EnVE algorithm. As the forecasting problem may itself be considered as a smoothing problem, it is, in fact, expected to find a ``smoothing'' ingredient at the heart of an algorithm of this sort. Various strategies are proposed and tested for accomplishing the required smoothing in the EnVE setting, and are tested on both a chaotic 1D PDE (the Kuramoto-Sivashinsky equation) as well as our in-house spectral 3D DNS/LES code, diablo.

  13. "You've Got the Power": Documentary Film as a Tool of Environmental Adult Education

    Science.gov (United States)

    Clover, Darlene E.

    2011-01-01

    Educators call for more creative means to combat the moribund narratives of contemporary environmentalism. Using visual methodology and environmental adult education theory, this article discusses how a documentary film titled "You've Got the Power" works to pose questions about complex environmental issues and develop critical thinking…

  14. Vědecké osobnosti a vedení ve vědě

    Czech Academy of Sciences Publication Activity Database

    Wiedermann, Jiří

    č. 3 (2005), s. 14-17 ISSN 1210-9525 Institutional research plan: CEZ:AV0Z10300504 Keywords : vědecké osobnosti * talent * grantový systém * vědecká excelence Subject RIV: AM - Education http://abicko.avcr.cz/archiv/2005/3/obsah/vedecke-osobnosti-a-vedeni-ve-vede.html

  15. cd4 changes in haart-naïve hiv positive pregnant women on haart

    African Journals Online (AJOL)

    boaz

    This study thus attempt an assessment of the pattern of immunologic (CD4) changes in naïve. HIV positive pregnant women, in the first two months of commencing HAART, with a view to possibly postulate CD4 response rate and recommend the ideal time to initiate HAARTin HIV positive pregnant patients. METHODOLOGY.

  16. Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

    DEFF Research Database (Denmark)

    Beer, Tomasz M; Armstrong, Andrew J; Rathkopf, Dana

    2017-01-01

    Enzalutamide significantly improved radiographic progression-free survival (rPFS) and overall survival (OS) among men with chemotherapy-naïve metastatic castration-resistant prostate cancer at the prespecified interim analysis of PREVAIL, a phase 3, double-blind, randomized study. We evaluated...

  17. Aristoteles Ve İbn Sînâ’nın Reenkarnasyonu Reddi

    Directory of Open Access Journals (Sweden)

    Hasan Özalp

    2013-06-01

    Full Text Available Bu makalede düşünce tarihinin iki önemli düşünürü Aristoteles ve İbn Sînâ’nın reenkarnasyon/tenasüh hakkındaki görüşlerini inceledik. Her iki düşünürde reenkar-nasyonu reddetmektedir. Konuyu ele almadan önce kaynak olmaları bakımından Aristoteles ve İbn Sînâ’dan önceki bazı filozofların ruh ve reenkarnasyon hakkındaki görüşlerini araştırdık. Daha sonra da her iki filozofun ruh tanımlarım belirledikten sonra reenkarnasyone niçin reddettiklerini ortaya koymaya çalıştık. Nihayetinde görüşlerinde ki benzer ve farklı noktaları tespit için bir karşılaştırma yaptık

  18. Düzce Yöresinde Su Kullanımı ve Tabansuyu

    Directory of Open Access Journals (Sweden)

    Selçuk ÖZMEN

    2014-06-01

    Full Text Available Bu çalışmada, Düzce yöresinde su kullanımı ve tabansuyu durumu irdelenmiştir. Yörede bulanan toplam tarım arazilerinin % 36’sı sulanmakta olup, bu arazilerde ağırlıklı olarak yüzey sulama yöntemi uygulanmaktadır. Yapılan çalışmalar sonucunda; bu yörede sulama ile ilgili daha önce yapılan çalışmaların yetersiz olduğu ve basınçlı sulama tekniklerinin uygulama oranın sadece % 5-10 aralığında değiştiği saptanmıştır. Bununla birlikte, yörenin değişken topografik yapısı nedeniyle kış ve ilkbahar aylarında taban suyunun arttığı gözlenmiştir. Yörede sulama ve tabansuyu kaynaklı tuzluluk problemi olmadığı belirlenmiştir

  19. Urine Osmolality in Treatment-naïve HIV-positive Subjects in ...

    African Journals Online (AJOL)

    2017-03-01

    Mar 1, 2017 ... commonly evaluated in routine clinical practice and in human ... the variables and urine osmolality and the strength of variables to ... function, and weight were common in treatment-naïve HIV subjects who had ... Nigeria, underweight and obesity, urine osmolality ..... associated with a salt-losing syndrome.

  20. NetRaVE: constructing dependency networks using sparse linear regression

    DEFF Research Database (Denmark)

    Phatak, A.; Kiiveri, H.; Clemmensen, Line Katrine Harder

    2010-01-01

    NetRaVE is a small suite of R functions for generating dependency networks using sparse regression methods. Such networks provide an alternative to interpreting 'top n lists' of genes arising out of an analysis of microarray data, and they provide a means of organizing and visualizing the resulting...

  1. Urine osmolality in treatment-naïve HIV-positive subjects in ...

    African Journals Online (AJOL)

    Urine osmolality is not commonly evaluated in routine clinical practice and in human immunodeficiency virus (HIV) subjects. The factors that influence urine osmolality have not been completely identified. The aim of this study was to evaluate urine osmolality in treatment‑naïve HIV subjects and to identify the factors that may ...

  2. Characteristics Predicting Dyslipidemia in Drug-naïve Type 2 Diabetes Patients

    Directory of Open Access Journals (Sweden)

    Shi-Dou Lin

    2006-09-01

    Conclusion: We recommend a more intensive monitoring of lipid levels in drug-naïve diabetic patients who possess the characteristics of alcohol consumption or older age (men, long duration of diabetes (women, and higher BMI or WHR (both genders.

  3. Water Retention Capacity of Argillite from the VE Test - Phase II at Mont Terri: Effect of Ventilation

    Energy Technology Data Exchange (ETDEWEB)

    Villar, M. V.; Fernandez, A. M.; Melon, A. M.

    2009-10-12

    The VE (ventilation) test carried out at the Mont Terri underground laboratory in Switzerland intended to evaluate in situ the behaviour of a consolidated clay formation when subjected to alternate periods of flow of wet and dry air during several months. For that, a 10-m gallery was excavated in the Opalinus Clay formation and carefully instrumented. Before and after a second ventilation phase boreholes were drilled. Samples were taken from the drill cores and were analysed from mineralogical and geochemical points of view. Also, the retention curves of these samples were determined in the laboratory following drying paths performed under free volume conditions at 20 degree centigrade, what is the content of this report. Although there are not large differences in the WRC of samples taken from different boreholes, at different distances from the gallery wall or before or after ventilation, those samples taken near the gallery wall and after ventilation tend to show a higher water retention capacity. This has been correlated to the higher salinity of the pore water of these samples, what increases their osmotic suction. This effect is attenuated towards high suctions. (Author) 10 refs.

  4. Water Retention Capacity of Argillite from the VE Test - Phase II at Mont Terri: Effect of Ventilation

    International Nuclear Information System (INIS)

    Villar, M. V.; Fernandez, A. M.; Melon, A. M.

    2009-01-01

    The VE (ventilation) test carried out at the Mont Terri underground laboratory in Switzerland intended to evaluate in situ the behaviour of a consolidated clay formation when subjected to alternate periods of flow of wet and dry air during several months. For that, a 10-m gallery was excavated in the Opalinus Clay formation and carefully instrumented. Before and after a second ventilation phase boreholes were drilled. Samples were taken from the drill cores and were analysed from mineralogical and geochemical points of view. Also, the retention curves of these samples were determined in the laboratory following drying paths performed under free volume conditions at 20 degree centigrade, what is the content of this report. Although there are not large differences in the WRC of samples taken from different boreholes, at different distances from the gallery wall or before or after ventilation, those samples taken near the gallery wall and after ventilation tend to show a higher water retention capacity. This has been correlated to the higher salinity of the pore water of these samples, what increases their osmotic suction. This effect is attenuated towards high suctions. (Author) 10 refs

  5. HEYBELİADA RUHBAN OKULU (HRO MESELESİ: SİYASA, MENFAAT, PARANOYA VE ETKİLER

    Directory of Open Access Journals (Sweden)

    Mete Kaan KAYAPINAR

    2017-11-01

    Full Text Available 1844 yılında Heybeliada’daki Umut Tepesi’nde açılan Heybeliada Ruhban Okulu, İstanbul’un fethi sonrası Türklerin hâkimiyetine girmesine rağmen, Osmanlı İmparatorluğu tarafından varlığı tutulan İstanbul Rum Ortodoks Patrikhanesi’nin doğrudan ilgi ve yetki alanında hareket eden bir kurumdur. Doğu Bloku’nun çöküşü ve küreselleşme süreçleriyle birlikte dinî değerlerin toplumlar nezdinde yükselişe geçmesi, dinin dünya siyasetinde öneminin artıp daha belirgin bir araç olarak kullanılması, Türkiye’de hem İstanbul Rum Ortodoks Patrikhanesi’ni hem de 1971’de kapatılmış olan HRO’yu gündeme taşımıştır. 1971 yılından bu yana kapalı olan Heybeliada Ruhban Okulu, özellikle bu tarihten sonra Türkiye, Yunanistan ve Patrikhane arasında siyasî, hukukî ve kültürel gelişme ve ihtilaflara konu olan temel kurumsal bir sorun konumu kazanmıştır. Hatta bu sorun, son yıllarda ABD ve AB’nin de müdahil olduğu uluslararası bir nitelik kazanmıştır. Bu çalışmanın amacı, her şeyden önce bir hukuk devleti olarak Türkiye Cumhuriyeti’nin Heybeliada Ruhban Okulu’nun geleceği konusunda uygulayabileceği siyasayı, söz konusu okulun geçmişten günümüze İstanbul Rum Ortodoks Patrikhanesi ile ilişkileri, statüleri ve Türk-Yunan sorunlarına etkileri açısından salt hukukî mülahazalar çerçevesinde irdeleyerek ortaya koymaktır.

  6. Yenidünyanın Bazı Fiziksel ve Kimyasal Özellikleri

    Directory of Open Access Journals (Sweden)

    Feramuz Özdemir

    2015-02-01

    Full Text Available Bu çalışmada Ege, Karadeniz ve özellikle Akdeniz bölgesinde yaygın olarak yetiştirilen yenidünyanın (eriobotrya japonnica L. bazı fiziksel ve kimyasal özellikleri belirlenmiştir.         Araştırmada materyal olarak Antalya Narenciye ve Seracılık Araştırma Enstitüsünün yenidünya bahçesinden sağlanan üç yerli, dört yabancı ve bir yabani olmak üzere toplam sekiz çeşit yenidünya kullanılmıştır. Yeme olumunda toplanan bu meyvelerin ağırlığı çeşide göre 14.00-33.46 g, meyve eti oranı %80.96-87.65, çekirdek sayısı 1-6 adet, çekirdek ağırlığı 2.17-5.35 g ve çekirdek ağırlık oranı %12.35-19.04 olarak saptanmıştır. Kimyasal nitelikler ise pulpta ortalama olarak suda çözünür kurumadde %11.08, pH 3.39, toplam asitlik (malik asit cinsinden 0.75, toplam şeker %9.78, indirgen şeker $9.29, sakkaroz %0.49, kül %0.42, formol sayısı 8.91 ve selüloz % 0.30 olarak bulunmuştur. Meyve pulpundaki mineral madde miktarları ise K 1246.8, Ca 273.1, Na 240.9, Mg 167, Fe 17.2, Cu 9.6, Mn 0.94 ve Zn 5.21 mg/kg olarak belirlenmiştir.

  7. YAZILIM TEKRAR KULLANIMI VE NESNEYE YÖNELİK YAKLAŞIM

    Directory of Open Access Journals (Sweden)

    Halil ŞENGONCA

    1995-02-01

    Full Text Available Yazılımın tekrar kullanımı, bir yazılım sisteminin geliştirilmesinde kullanılan bilginin ve ürünlerin, başka bir yazılım sistemi için kullanılmasıdır. Yazılımın tekrar kullanımı için kaynak kod bileşenlerinden oluşan bir kütüphane ve karmaşık sistemlerin bu yapı bloklarından oluşturulması fikri, ilk olarak 1968'te Dough McIlroy tarafından önerilmiştir. Günümüzde programlama dilleri, kullanılan teknikler ve araçlar çok değişmesine rağmen yazılımın tekrar kullanımı yazılım geliştirme maliyetlerini azaltmak ve kaliteyi yükseltmek için hala bir çözüm olarak görülmektedir. Nesneye yönelik programlama, kalıtım, koruma gibi özellikleriyle, kaynak kod bileşenlerinin oluşturulmasını ve kullanımını desteklemektedir. Yine de yazılım tekrar kullanımını bir kuruluş düzeyinde gerçekleştirmek için planlı ve koordineli bir programa gereksinim vardır. Bu makalede, yazılım tekrar kullanımı tanımlanmış ve nesneye yönelik yaklaşım ile yazılım tekrar kullanımını amaçlayan bir yazılım geliştirme süreci tanıtılmıştır. Ayrıca bir kuruluşun yazılım tekrar kullanımını kurumsallaştırma süreci için bir strateji önerilmiştir.

  8. Gabriel Tarde ve Medya-Toplum İlişkisini Yeniden Keşfetmek

    Directory of Open Access Journals (Sweden)

    Murat Sadullah Çebi

    2013-09-01

    Full Text Available ÖzBu çalışmanın amacı, Fransız sosyolog Gabriel Tarde’ın geliştirdiği ‘kamusal alan modeli’ üzerinden medya ve toplum ilişkisini yeniden keşfetmek, anlamak ve açıklamaktır. Tarde’ın kamusal alan modeli, karşılıklı etkileşen dört unsurdan oluşur: Basın, sohbet, kamuoyu, eylem. Tarde, modern toplumda basına önemli işlevler yükler. Tarde’a göre basın; bilgili, eleştirel ve rasyonel bir kamunun ortaya çıkmasını ve gelişmesini sağlamıştır. İkinci olarak; kahvehane ve salonlarda cereyan eden bir kamusal tartışma ve müzakere biçimine, yani sohbetlere zemin oluşturmuştur. Üçüncü olarak; kamuoyunu dillendirmiş ve oluşturmuştur. Dördüncü olarak; bireylerin sosyal, politik ve ekonomik süreçlerdeki seçim ve kararlarını etkilemiştir. Nihayetinde, zihinlerde hayalî bir kurgu olarak millet ve milliyet fikrini oluşturmuştur. Araştırmada; Tarde’ın kamusal alan modelinin, iletişim biliminde ‘iki aşamalı iletişim akışı modeli’ olarak bilinen ‘sınırlı medya etkileri modeli’nin ilk örneklerinden biri olduğu sonucuna ulaşılacaktır. AbstractThe purpose of this study is to rediscover, to understand and to interpret, relationships between the mass media and society through public sphere model developed by French sociologist Gabriel Tarde. Tarde’s public sphere model consists of four elements: Press, conversation, public opinion and action. Tarde attributed important roles to press in modern society. Firstly, according to Tarde press provided to emerge and to develop of a knowledgeable, critical and rational public. Secondly, it formed a basis for public discussions and deliberations, in other words for conversations that took place in coffee houses and saloons. Thirdly, it expressed and created public opinion. Fourthly, it determined choices and decisions of people in social, economic and political processes. Lastly, it created the idea of nation and nationality

  9. Organik Tavukçulukta Mera Kompozisyonu, Besleme ve Barındırma Teknikleri

    Directory of Open Access Journals (Sweden)

    Hasan Eleroğlu

    2014-01-01

    Full Text Available Dünya’daki gelişmelere paralel olarak, Türkiye’de de organik tavukçuluk sektöründe gelişmeler yaşanmaktadır. Son yıllarda artan taleplerin karşılanması amacıyla üretim artışı söz konusu olup, yeni organik işletmeler sayısında artış gözlenmektedir. Hayvanların besin maddesi ihtiyaçlarının belli bir kısmının meradan sağlanması için yerel bitkilerden yararlanılarak, uygun mera kompozisyonunun ekonomik üretimi destekleyecek şekilde oluşturulması gerekmektedir. Bununla birlikte, çevre koşulları ve barındırma tekniklerinin kanatlının performansı, sağlığı, refahı, ürün kalitesi üzerine etkisi bulunmaktadır. Bu nedenle çevre koşulları ve barındırma tekniklerinin, yerel koşullara uyumlu ve organik standartları sağlayacak şekilde düzenlenmesi gerekmektedir. Hayvanların günlük besin maddesi ihtiyaçlarının dengeli olarak karşılanmasında, hayvanların severek tükettikleri buğdaygil ve baklagil yem bitkileri yanında otlatmaya dayanıklı endemik bitkilerden oluşan karışımlardan yararlanılarak, mera kompozisyonu belirlenmelidir. Sabit ve taşınır barındırma sistemlerinde kullanılacak malzemelerin organik üretim standartlarına uygun olmalıdır. Kümes içi ve mera donanımları arasında bulunan yemlik ve sulukların organizasyonunda yöresel iklim koşulları dikkate alınmalı, özellikle ısıtma sistemlerinde aydınlatma yapmayan ısı kaynaklarının seçilmesi gerekmektedir. Yabani kuş ve yırtıcı hayvanlardan korunma amaçlı geliştirilen sistemler üzerinde durulmalı, ürün elde etme ve değerlendirme aşamasında, ürün kalitesinin maksimum düzeyde korunabileceği uygulamalar üzerinde durulmalıdır. Bu çalışmada, organik tavukçuluk üzerinde durularak, örnek olarak Sivas koşullarında organik etlik piliç üretiminde kullanılmak üzere oluşturulan mera kompozisyonu ile birlikte organik tavuk yetiştirmede kullanılan barındırma sistemi

  10. 75 FR 5108 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2010-02-01

    ... Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park Service... funerary objects in the possession and control of the University of Wyoming, Anthropology Department, Human... of Wyoming, Anthropology Department, Human Remains Repository professional staff in consultation with...

  11. Ortaçağ ve Sonrası Muş İli Yüzey Araştırması -2010- Varto

    Directory of Open Access Journals (Sweden)

    Bülent Nuri KILAVUZ

    2013-03-01

    Full Text Available AbstractThe research carried out with the permission of General Directorate of Monuments and Museums, Culture and Tourism Ministry of Turkish Republic, between 9 to 26 July 2010 in the center of Muş, Varto, Korkut and Hasköy towns.In the research, cultural assets which were three churches, a store, a fountain, monument consisting of six houses and thirteen cemeteries were identified and examined.The houses in the center of Muş are generally made of mud brick with two-storey. The houses at Minaret, the castle and the River districts are disappearing rapidly, because they remain in the center of the city. They indicate the characteristic feature of Muş especially with front-side arrangements.The tombstones found in Varto district are noteworthy with human and animal figure forms. The tombstones identified in villages of Hasköy and Korkut towns stand with the sword and shield motifs.Memorial monuments and tombstones vary in terms of materials, forms and style according to region and periods. The works identified usually belong to the Ottoman (XVI-XIX centuries period.The searched cemeteries were found to be different from each other. It is important to demonstrate the richness of the geography of Muş. Some of the motifs over the Headstones indicate differences, especially compared to other provinces in the region.Historical graves in the cemetery are rapidly destroyed by natural and human factors gradually. In addition, all new burials in cemeteries today increase the destruction.ÖzetT.C. Kültür ve Turizm Bakanlığı, Kültür Varlıkları ve Müzeler Genel Müdürlüğü’nün izinleri ile 09-26 Temmuz 2010 tarihleri arasında Muş merkez, Varto, Korkut ve Hasköy ilçelerinin köylerinde gerçekleştirilmiştir.Araştırmada; üç kilise, bir depo, bir çeşme, altı evden oluşan anıt eser ve on üç mezarlıktan oluşan kültür varlıkları tespit edilerek incelenmiştir.Muş merkezdeki evler genellikle kerpiç malzemeli ve iki

  12. Rabies virus infection in Eptesicus fuscus bats born in captivity (naïve bats.

    Directory of Open Access Journals (Sweden)

    April D Davis

    Full Text Available The study of rabies virus infection in bats can be challenging due to quarantine requirements, husbandry concerns, genetic differences among animals, and lack of medical history. To date, all rabies virus (RABV studies in bats have been performed in wild caught animals. Determining the RABV exposure history of a wild caught bat based on the presence or absence of viral neutralizing antibodies (VNA may be misleading. Previous studies have demonstrated that the presence of VNA following natural or experimental inoculation is often ephemeral. With this knowledge, it is difficult to determine if a seronegative, wild caught bat has been previously exposed to RABV. The influence of prior rabies exposure in healthy, wild caught bats is unknown. To investigate the pathogenesis of RABV infection in bats born in captivity (naïve bats, naïve bats were inoculated intramuscularly with one of two Eptesicus fuscus rabies virus variants, EfV1 or EfV2. To determine the host response to a heterologous RABV, a separate group of naïve bats were inoculated with a Lasionycteris noctivagans RABV (LnV1. Six months following the first inoculation, all bats were challenged with EfV2. Our results indicate that naïve bats may have some level of innate resistance to intramuscular RABV inoculation. Additionally, naïve bats inoculated with the LnV demonstrated the lowest clinical infection rate of all groups. However, primary inoculation with EfV1 or LnV did not appear to be protective against a challenge with the more pathogenic EfV2.

  13. Learning Content Management Systems

    Directory of Open Access Journals (Sweden)

    Tache JURUBESCU

    2008-01-01

    Full Text Available The paper explains the evolution of e-Learning and related concepts and tools and its connection with other concepts such as Knowledge Management, Human Resources Management, Enterprise Resource Planning, and Information Technology. The paper also distinguished Learning Content Management Systems from Learning Management Systems and Content Management Systems used for general web-based content. The newest Learning Content Management System, very expensive and yet very little implemented is one of the best tools that helps us to cope with the realities of the 21st Century in what learning concerns. The debates over how beneficial one or another system is for an organization, can be driven by costs involved, efficiency envisaged, and availability of the product on the market.

  14. Building and Contents Insurance.

    Science.gov (United States)

    Freese, William C.

    Insurance coverage of school buildings and contents is becoming increasingly difficult to obtain, and increases of 50 percent or more in the premium are not uncommon. Methods of reducing premium increases are outlined in this speech. (MLF)

  15. Selenium content of mushrooms.

    Science.gov (United States)

    Stijve, T

    1977-07-29

    The selenium contents of 83 species of wild mushrooms were determined by oxygen combustion of the sample, followed by conversion of selenite to bromopiazselenol and final estimation by electron capture gas-liquid chromatography. Selenium concentration were found to range from 0.012-20.0 mg/kg dry weight. Selenium content was species-dependent. High concentrations were found in Agaricaceae and in certain Boletaceae of the genus Tubiporus, whereas in Russulaceae, Amanitaceae and Cantharellaceae selenium-rich species were absent or rare. Ascomycetes and all mushrooms growing on wood had a very low selenium content. The highest selenium concentrations (up to 20 ppm) were found in Boletus (Tubiporus) edulis, a most popular edible mushroom. Analyses of various parts of carpophores of B. edulis, Suillus luteus and Amanita muscaria indicate that in all three species the stalk contains less selenium than the fleshy part of the cap. In Boletus and Suillus the highest selenium content was found in the tubes.

  16. INVESTIGATION OF PRIMARY FIFTH GRADE STUDENTS’KNOWLEDGE AND PERCEPTION LEVEL OF NASREDDIN HODJA AND KELOĞLAN İLKÖĞRETİM BEŞİNCİ SINIF ÖĞRENCİLERİNİN NASREDDİN HOCA VE KELOĞLAN’A İLİŞKİN BİLGİ VE ALGI DÜZEYLERİNİN İNCELENMESİ

    Directory of Open Access Journals (Sweden)

    Erol DURAN

    2012-06-01

    Full Text Available This study aims to investigate how primary fifth grade students'levels of knowledge and perception about Nasreddin Hodja and Keloğlan. This study were tried to find answer of these question: “Which is the level of students' knowledge about Nasreddin Hodja and Keloğlan?”, “Which sources students learned Keloğlan tales?”, “Can Students detect correctly perceive the message to be given in jokes or tales”. In this study, the descriptive model; content and descriptive analysis technique was used. The study group is 172 primary fifth grade students chosen at random in Uşak city center. In this study, a data collection tool, Investigation of Primary Fifth Grade Students’ Knowledge and Perception Related toNasreddin Hodja and Keloğlan, developed by the researcher, was used. According to the survey, students define Nasreddin Hodja as “funny, reverse, donkey riding, witty and knowledgeable”. But some students define Nasreddin Hodja as "a liar and deceitful. This rate for the number of students cannot be underestimated. Students define Keloğlan as “bald, cartoon character and intelligent”. In addition, in the students responses, Keloğlan "lazy and disobedient" features stand out. More than half of the students have been failed or very failed to percept the message to be given in Nasreddin Hodja jokes. However, more than half of the students have been success or very success to percept the message to be given in Keloğlan tales. İlköğretim beşinci sınıf öğrencilerinin Nasreddin Hoca ve Keloğlan ile ilgili bilgi ve algı düzeylerini belirlemeyi amaçlayan bu araştırmada, “Öğrencilerin Nasreddin Hoca ve Keloğlan ile ilgili bilgi masallarını hangi kaynaklardan öğrendikleri” ve “Fıkralarda veya masallarda verilmek istenen mesajı doğru algılayıp algılayamadıkları” araştırılmaya çalışılmıştır. Araştırmada, betimsel tarama modeli; içerik ve betimsel analiz tekniği kullanılmıştır. Ara

  17. 25 CFR 291.15 - How long do Class III gaming procedures remain in effect?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How long do Class III gaming procedures remain in effect... ENTERPRISES CLASS III GAMING PROCEDURES § 291.15 How long do Class III gaming procedures remain in effect? Class III gaming procedures remain in effect for the duration specified in the procedures or until...

  18. METHODS OF CONTENTS CURATOR

    Directory of Open Access Journals (Sweden)

    V. Kukharenko

    2013-03-01

    Full Text Available Content curated - a new activity (started in 2008 qualified network users with process large amounts of information to represent her social network users. To prepare content curators developed 7 weeks distance course, which examines the functions, methods and tools curator. Courses showed a significant relationship success learning on the availability of advanced personal learning environment and the ability to process and analyze information.

  19. The use of decision trees and naïve Bayes algorithms and trace element patterns for controlling the authenticity of free-range-pastured hens' eggs.

    Science.gov (United States)

    Barbosa, Rommel Melgaço; Nacano, Letícia Ramos; Freitas, Rodolfo; Batista, Bruno Lemos; Barbosa, Fernando

    2014-09-01

    This article aims to evaluate 2 machine learning algorithms, decision trees and naïve Bayes (NB), for egg classification (free-range eggs compared with battery eggs). The database used for the study consisted of 15 chemical elements (As, Ba, Cd, Co, Cs, Cu, Fe, Mg, Mn, Mo, Pb, Se, Sr, V, and Zn) determined in 52 eggs samples (20 free-range and 32 battery eggs) by inductively coupled plasma mass spectrometry. Our results demonstrated that decision trees and NB associated with the mineral contents of eggs provide a high level of accuracy (above 80% and 90%, respectively) for classification between free-range and battery eggs and can be used as an alternative method for adulteration evaluation. © 2014 Institute of Food Technologists®

  20. Qualitative Content Analysis

    Directory of Open Access Journals (Sweden)

    Satu Elo

    2014-02-01

    Full Text Available Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studies, our own experiences, and methodological textbooks. Trustworthiness was described for the main qualitative content analysis phases from data collection to reporting of the results. We concluded that it is important to scrutinize the trustworthiness of every phase of the analysis process, including the preparation, organization, and reporting of results. Together, these phases should give a reader a clear indication of the overall trustworthiness of the study. Based on our findings, we compiled a checklist for researchers attempting to improve the trustworthiness of a content analysis study. The discussion in this article helps to clarify how content analysis should be reported in a valid and understandable manner, which would be of particular benefit to reviewers of scientific articles. Furthermore, we discuss that it is often difficult to evaluate the trustworthiness of qualitative content analysis studies because of defective data collection method description and/or analysis description.

  1. Mummified remains from the Archaeological Museum in Zagreb, Croatia - Reviewing peculiarities and limitations of human and non-human radiological identification and analysis in mummified remains.

    Science.gov (United States)

    Petaros, Anja; Janković, Ivor; Cavalli, Fabio; Ivanac, Gordana; Brkljačić, Boris; Čavka, Mislav

    2015-10-01

    Forensic protocols and medico-legal techniques are increasingly being employed in investigations of museological material. The final findings of such investigations may reveal interesting facts on historical figures, customs and habits, as well as provide meaningful data for forensic use. Herein we present a case review where forensic experts were requested to identify taxonomic affinities, stage of preservation and provide skeletal analysis of mummified non-human archaeological remains, and verify whether two mummified hands are human or not. The manuscript offers a short review on the process and particularities of radiological species identification, the impact of post-mortem changes in the analysis and imaging of mummified remains as well as the macroscopical interpretation of trauma, pathology and authenticity in mummified remains, which can all turn useful when dealing with forensic cases. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  2. HIV-1 integrase inhibitor resistance among treatment naïve patients in the West of Scotland.

    Science.gov (United States)

    Bradley-Stewart, A; Urcia, C; MacLean, A; Aitken, C; Gunson, R

    2017-07-01

    Transmitted integrase inhibitor resistance is rare, with only a small number of cases reported world-wide to date. The aim of this study was to assess whether transmitted integrase inhibitor resistance has occurred in Scotland and if so, could there be a case for performing genotypic integrase resistance testing at baseline. The study population consisted of 106 treatment naïve, newly diagnosed, HIV positive patients. The patient samples were collected between October 2015 and March 2016 at the time of HIV diagnosis and prior to initiation of anti-retroviral therapy. The integrase region was amplified and sequenced. We detected integrase inhibitor resistance (T66I/T) at baseline in one patient sample. This is a non-polymorphic mutation seen in patients receiving elvitegravir which confers high-level resistance to elvitegravir and intermediate resistance to raltegravir. A further 10 patients had accessory mutations which have minimal or no effect on susceptibility to integrase inhibitors. Transmitted integrase inhibitor resistance remains rare. The results of the present study do not support performing integrase resistance testing at baseline. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  3. Assessing sandy beach macrofaunal patterns along large-scale environmental gradients: A Fuzzy Naïve Bayes approach

    Science.gov (United States)

    Bozzeda, Fabio; Zangrilli, Maria Paola; Defeo, Omar

    2016-06-01

    A Fuzzy Naïve Bayes (FNB) classifier was developed to assess large-scale variations in abundance, species richness and diversity of the macrofauna inhabiting fifteen Uruguayan sandy beaches affected by the effects of beach morphodynamics and the estuarine gradient generated by Rio de la Plata. Information from six beaches was used to estimate FNB parameters, while abiotic data of the remaining nine beaches were used to forecast abundance, species richness and diversity. FNB simulations reproduced the general increasing trend of target variables from inner estuarine reflective beaches to marine dissipative ones. The FNB model also identified a threshold value of salinity range beyond which diversity markedly increased towards marine beaches. Salinity range is suggested as an ecological master factor governing distributional patterns in sandy beach macrofauna. However, the model: 1) underestimated abundance and species richness at the innermost estuarine beach, with the lowest salinity, and 2) overestimated species richness in marine beaches with a reflective morphodynamic state, which is strongly linked to low abundance, species richness and diversity. Therefore, future modeling efforts should be refined by giving a dissimilar weigh to the gradients defined by estuarine (estuarine beaches) and morphodynamic (marine beaches) variables, which could improve predictions of target variables. Our modeling approach could be applied to a wide spectrum of issues, ranging from basic ecology to social-ecological systems. This approach seems relevant, given the current challenge to develop predictive methodologies to assess the simultaneous and nonlinear effects of anthropogenic and natural impacts in coastal ecosystems.

  4. Karhunen-Loève treatment to remove noise and facilitate data analysis in sensing, spectroscopy and other applications.

    Science.gov (United States)

    Zaharov, V V; Farahi, R H; Snyder, P J; Davison, B H; Passian, A

    2014-11-21

    Resolving weak spectral variations in the dynamic response of materials that are either dominated or excited by stochastic processes remains a challenge. Responses that are thermal in origin are particularly relevant examples due to the delocalized nature of heat. Despite its inherent properties in dealing with stochastic processes, the Karhunen-Loève expansion has not been fully exploited in measurement of systems that are driven solely by random forces or can exhibit large thermally driven random fluctuations. Here, we present experimental results and analysis of the archetypes (a) the resonant excitation and transient response of an atomic force microscope probe by the ambient random fluctuations and nanoscale photothermal sample response, and (b) the photothermally scattered photons in pump-probe spectroscopy. In each case, the dynamic process is represented as an infinite series with random coefficients to obtain pertinent frequency shifts and spectral peaks and demonstrate spectral enhancement for a set of compounds including the spectrally complex biomass. The considered cases find important applications in nanoscale material characterization, biosensing, and spectral identification of biological and chemical agents.

  5. Patrick Mccabe’in Plüton’da Kahvaltı ve Jeffrey Eugenides’in Middlesex adlı romanlarında cinsel kimlik, aile ve göç

    OpenAIRE

    DEMİR, Elif

    2016-01-01

    Cinsiyet  ve  toplumsal  cinsiyet  kavramları  merak  ve  ilham  uyandıran  yapısıyla  pek  çok  bilimsel  alanın  ilgi  konusu  olmuş  ve  kadın/erkek  ikiliği  dışına  çıkan  bireylere  atfedilen  ‘queer’  kavramıyla  edebi  imgelemde &nbs...

  6. Metil ve Etil Ester Kullanılan Bir Common-Rail Dizel Motorda Performans, Yanma ve Enjeksiyon Karakteristiklerinin Karşılaştırılması

    Directory of Open Access Journals (Sweden)

    Ertan ALPTEKİN

    2017-02-01

    Full Text Available Biyodizel, dünyada kullanımı yaygınlaşan yenilebilir ve alternatif bir dizel yakıtıdır. Biyodizel üretiminde kullanılan alkol büyük önem arz etmekte ve üretilen biyodizelin yakıt özelliklerini doğrudan etkilemektedir. Farklı yakıt özellikleri, dizel motorlarda farklı yakıt enjeksiyon ve yanma karakteristiklerine sebep olabilmektedir. Bu nedenle bu çalışmada, metanol ve etanol kullanılarak üretilen iki farklı ester yakıtı ve saf motorin, common-rail yakıt enjeksiyon sistemine sahip bir dizel motorda üç farklı motor yükü (50 Nm, 100 Nm ve 150 Nm ve 2000 dev/dk sabit motor devrinde deney yakıtı olarak kullanılmıştır. Bu yakıtların performans, yanma ve yakıt enjeksiyon analizi karşılaştırmalı olarak gerçekleştirilmiştir. Deney sonuçlarına göre, etil ve metil ester kullanımıyla özgül yakıt tüketimi (ÖYT motorine kıyasla artış göstermiştir. Etil ve metil ester yakıtlarının silindir içi basıncı ve ısı yayılımı değerleri tüm deney şartlarında motorine kıyasla daha yüksek olmuştur. Yakıt enjeksiyon karakteristikleri, yakıt tipi ve motor yüküne bağlı olarak farklılık göstermiştir.

  7. Review of the Dinosaur Remains from the Middle Jurassic of Scotland, UK

    Directory of Open Access Journals (Sweden)

    Neil D. L. Clark

    2018-02-01

    Full Text Available Dinosaurs are rare from the Middle Jurassic worldwide. The Isle of Skye, is the only place in Scotland thus far to have produced dinosaur remains. These remains consist mainly of footprints, but also several bones and teeth. These Bajocian and Bathonian remains represent an important collection of a basal eusauropod, early examples of non-neosauropod and possible basal titanosauriform eusauropods, and theropod remains that may belong to an early coelurosaur and a possible megalosaurid, basal tyrannosauroid, or dromaeosaurid. The footprints from here also suggest a rich and diverse dinosaur fauna for which further better diagnosable remains are likely to be found.

  8. Tad, Koku ve Renk Katkısı Olarak Kırmızı Biber

    Directory of Open Access Journals (Sweden)

    Atillâ Akgül

    2015-02-01

    Full Text Available Kırmızıbiber, dünya çapında kültürü yapılan ve kullanılan en önemli baharatlardan biridir. Değişik kullanım şekillerinin yanısıra, bölge ve ülkelere göre değişen çok sayıda gıda ürününde yer alması, diğer çoğu baharatlardan farklı olarak yakıcılık ve renk maddelerince zengin olması kırmızıbiberi vazgeçilemez bir tad, koku ve renk materyali durumuna getirmiştir. Bununla birlikte botanik kaynakları ve özellikleri ile ticaret ve bölgesel tüketimlerde çok çeşitli isimle bilinmesi gibi karışıklıklar henüz tam olarak standart çözümlere kavuşturulamamıştır. Yaygınlık kazanan bazı sınıflama ve isimlemelerin kullanılması sürmektedir.

  9. Tie Content in Professional Networks

    DEFF Research Database (Denmark)

    Zarzecka, Olga

    in resource exchanges and the effect of these differences on the number of, and extent to which, resources are provided by a network tie. Chapter 3 explores how firm underperfomance and social identity with corporate elite alter types of resources a network tie provides. Chapter 4 focuses on a tie’s internal......Professional networks of senior managers have indisputable value for them as well as for their organizations. In recent years, much attention has been given to the structure of these networks as it reflects senior managers’ opportunity to access valuable resources. Surprisingly, the actual...... resources that senior managers acquire through their network ties, i.e. the tie content, remain heavily understudied. Hence, the purpose of this dissertation is to answer the following question: What resources flow through informal ties in senior managers’ professional networks, and why? The first chapter...

  10. Bazı Meşe ve Gül Türlerinde Galli ve Galsiz Bireylerdeki, Total Protein İçeriğinin Farklı Yöntemler Kullanılarak Araştırılması

    Directory of Open Access Journals (Sweden)

    Sevgi Daştan

    2012-02-01

    Full Text Available Özet. Parazit veya simbiyoz olarak bitki üzerinde yaşayan böcek, nematod, akar, bakteri ya da mantarların neden olduğu tahriş ve beslenme fizyolojisinden doğan olumsuzluklara karşı bitkilerin savunma tepkimesi olarak oluşturdukları anormal büyüme şekli gal olarak tanımlanmaktadır. En kompleks, en iyi organize olmuş gallerin birçoğu, gal arıları (Hymenoptera: Cynipidae tarafından meydana getirilirler. En çok tanınan cynipid galleri gül ve meşelerde yer almaktadır. Bu çalışmada; Sivas çevresinde yetişen, bazı meşe ve gül türlerinin, gal oluşturmayan ve yoğun olarak sürgün ve meyva gali oluşturan bireylerinden yaprak, meyva ve sürgün gal örnekleri toplanmıştır. Yaprak, meyva ve gallerdeki total protein miktarları, Bradford Mikro Assay, Biüret, Lowry yöntemleri ve ayrıca Ultraviyole (UV spektrofotometresi kullanılarak 280 nm de ölçümleri yapılmak suretiyle hesaplanmıştır. Bu şekilde elde edilen veriler üzerinden hem galli ve galsiz bireyler arasındaki protein miktarları açısından farklılıklar hem de kullanılan dört farklı yöntem arasındaki farklılıklar karşılaştırılmıştır. Yapılan deneyler sonucunda; galli bireylerdeki total protein miktarının galsiz bireylere göre anlamlı şekilde fazla olduğu saptanmıştır. Yine meşelerdeki protein içeriğinin güllerdeki protein içeriğine göre yaklaşık 2 katı değerlerde olduğu tespit edilmiştir. Aylara göre protein içeriğindeki farklılıklara baktığımızda ise, meşeler için eylül ayında, kuşburnu bitkisi için ise ağustos ayında daha fazla protein içeriği tespit edilmiştir. Anahtar Kelimeler: Gal, Rosa sp., Quercus sp., Cynipidae, Total protein içeriği Abstract. Plant galls are an abnormal growth pattern that plants develop as a defense reaction to irritations and negative nutritional physiology caused by insects, nematodes, mites, bacteria and fungi living in a parasitic or symbiotic

  11. Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.

    Science.gov (United States)

    Yan, Meiping; Zhang, Xinhua; Chen, Ao; Gu, Wei; Liu, Jie; Ren, Xiaojiao; Zhang, Jianping; Wu, Xiaoxiong; Place, Aaron T; Minshall, Richard D; Liu, Guoquan

    2017-11-01

    Intercellular adhesion molecule-1 (ICAM-1) mediates the firm adhesion of leukocytes to endothelial cells and initiates subsequent signaling that promotes their transendothelial migration (TEM). Vascular endothelial (VE)-cadherin plays a critical role in endothelial cell-cell adhesion, thereby controlling endothelial permeability and leukocyte transmigration. This study aimed to determine the molecular signaling events that originate from the ICAM-1-mediated firm adhesion of neutrophils that regulate VE-cadherin's role as a negative regulator of leukocyte transmigration. We observed that ICAM-1 interacts with Src homology domain 2-containing phosphatase-2 (SHP-2), and SHP-2 down-regulation via silencing of small interfering RNA in endothelial cells enhanced neutrophil adhesion to endothelial cells but inhibited neutrophil transmigration. We also found that VE-cadherin associated with the ICAM-1-SHP-2 complex. Moreover, whereas the activation of ICAM-1 leads to VE-cadherin dissociation from ICAM-1 and VE-cadherin association with actin, SHP-2 down-regulation prevented ICAM-1-VE-cadherin association and promoted VE-cadherin-actin association. Furthermore, SHP-2 down-regulation in vivo promoted LPS-induced neutrophil recruitment in mouse lung but delayed neutrophil extravasation. These results suggest that SHP-2- via association with ICAM-1-mediates ICAM-1-induced Src activation and modulates VE-cadherin switching association with ICAM-1 or actin, thereby negatively regulating neutrophil adhesion to endothelial cells and enhancing their TEM.-Yan, M., Zhang, X., Chen, A., Gu, W., Liu, J., Ren, X., Zhang, J., Wu, X., Place, A. T., Minshall, R. D., Liu, G. Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction. © FASEB.

  12. Combination antiretroviral therapy improves cognitive performance and functional connectivity in treatment-naïve HIV-infected individuals.

    Science.gov (United States)

    Zhuang, Yuchuan; Qiu, Xing; Wang, Lu; Ma, Qing; Mapstone, Mark; Luque, Amneris; Weber, Miriam; Tivarus, Madalina; Miller, Eric; Arduino, Roberto C; Zhong, Jianhui; Schifitto, Giovanni

    2017-10-01

    Our study aimed to investigate the short-term effect of combination antiretroviral therapy (cART) on cognitive performance and functional and structural connectivity and their relationship to plasma levels of antiretroviral (ARV) drugs. Seventeen ARV treatment-naïve HIV-infected individuals (baseline mean CD4 cell count, 479 ± 48 cells/mm 3 ) were age matched with 17 HIV-uninfected individuals. All subjects underwent a detailed neurocognitive and functional assessment and magnetic resonance imaging. HIV-infected subjects were scanned before starting cART and 12 weeks after initiation of treatment. Uninfected subjects were assessed once at baseline. Functional connectivity (FC) was assessed within the default mode network while structural connectivity was assessed by voxel-wise analysis using tract-based spatial statistics (TBSS) and probabilistic tractography within the DMN. Tenofovir and emtricitabine blood concentration were measured at week 12 of cART. Prior to cART, HIV-infected individuals had significantly lower cognitive performance than control subjects as measured by the total Z-score from the neuropsychological tests assessing six cognitive domains (p = 0.020). After 12 weeks of cART treatment, there remained only a weak cognitive difference between HIV-infected and HIV-uninfected subjects (p = 0.057). Mean FC was lower in HIV-infected individuals compared with those uninfected (p = 0.008), but FC differences became non-significant after treatment (p = 0.197). There were no differences in DTI metrics between HIV-infected and HIV-uninfected individuals using the TBSS approach and limited evidence of decreased structural connectivity within the DMN in HIV-infected individuals. Tenofovir and emtricitabine plasma concentrations did not correlate with either cognitive performance or imaging metrics. Twelve weeks of cART improves cognitive performance and functional connectivity in ARV treatment-naïve HIV-infected individuals with relatively

  13. Osmanlı Seferlerinde Organizasyon Ve Lojistik The Organization And Logistics Of The Ottoman Flights

    Directory of Open Access Journals (Sweden)

    Uğur KURTARAN

    2012-12-01

    Full Text Available Understanding how the army, one of Ottoman Empire’s main dynamics and whose number reached over hundreds of thousands on occasions, was organized and how its needs were taken care of is not only important in better understanding the founding and the rising of the state but also important in better understanding the reasons for its downfall. Because just like other states founded throughout history, the political history and development of the Ottoman State has beenshaped in connection to its military operations. The success of themilitary operations is dependent on logistics activities, the preparationsand organizations before the military campaign. Indeed, when theOttoman State decided to go in to war, it has made importantpreparations in elevating the administrative and logistical organizationin the country to a more effective level. These preparations beforemilitary campaigns and strategies implemented called today as logisticshave led to the success of the military campaigns carried out in theOttoman State. At this point, the preparations implemented before thecampaigns play a big role in the growth of the state and expansion ofthe boundaries of the empire. So the key element that won or lost thewars for the Ottoman State throughout history was the far better prewarpreparations and organizations they applied much moresuccessfully than their contemporaries. Knowing how and in what waysthese preparations were implemented in the Ottoman State will broadenour perspective and help us better understand the underlying causes inOttoman victories. This study has been prepared in accordance withthese goals and objectives. In this study, it is intended to put forth howthe Ottomans did their preparations before and during the war and togive a different perspective to the current knowledge and experience inthe light of new resources. Osmanlı Devleti’nin temel dinamiklerinden birisi olan ve sayıları bazı dönemlerde yüz binleri geçen ordusunun

  14. Budget Impact of Enzalutamide for Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer.

    Science.gov (United States)

    Bui, Cat N; O'Day, Ken; Flanders, Scott; Oestreicher, Nina; Francis, Peter; Posta, Linda; Popelar, Breanna; Tang, Hong; Balk, Mark

    2016-02-01

    Prostate cancer is expected to account for approximately one quarter of all new diagnoses of cancer in American men in 2015. The cost of prostate cancer care is expected to reach $15.1 billion by the year 2020, up from $11.9 billion in 2010. Given the high burden of prostate cancer, health care payers are interested in quantifying the potential budget impact of new therapies. To estimate the budget impact of enzalutamide for the treatment of chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) from a U.S. payer perspective. A model was developed to assess the budget impact of enzalutamide for treatment of chemotherapy-naïve mCRPC patients in a hypothetical 1-million-member U.S. health plan over a 1-year time horizon. Comparators included abiraterone acetate, sipuleucel-T, radium Ra 223 dichloride, and docetaxel. Epidemiologic data, including National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) incidence rates, were used to estimate the number of chemotherapy-naïve mCRPC patients. Dosing, administration, duration of therapy, and adverse event rates were based on package inserts and pivotal studies. Drug costs were obtained from RED BOOK and Centers for Medicare & Medicaid Services (CMS) average sales price pricing files, costs of administration and monitoring from the CMS physician fee schedule, and adverse events from the Agency for Healthcare Research and Quality Healthcare Cost and Utilization Project and published literature. Market shares were estimated for each comparator before and after adoption of enzalutamide. The incremental aggregate budget impact, per patient per year (PPPY), per patient per month (PPPM), and per member per month (PMPM), was calculated. One-way sensitivity analyses were performed. In a population of 115 chemotherapy-naïve mCRPC patients, adopting enzalutamide had an annual incremental budget impact of $510,641 ($4,426 PPPY, $369 PPPM, and $0.04 PMPM). Results were most sensitive to

  15. GELECEĞİN MALİYETLERİNİN KONTROLÜNDE YENİ BİR YAKLAŞIM: HEDEF VE KAIZEN MALİYETLEME

    Directory of Open Access Journals (Sweden)

    ZEYNEP TÜRK

    2013-05-01

    Full Text Available Firmalar tarafından modern üretim teknolojilerinin kullanılması yeni maliyet ve yönetim muhasebesi yöntemlerinin geliştirilmesine ve uygulanmasına neden olmuştur. Hedef ve kaizen maliyetleme bu yeni sistemlerin örneklerindendir. Japon elektronik ve araç üreticileri hedef ve kaizen maliyetlemeyi yoğun bir şekilde kullanmışlardır. Hedef ve kaizen maliyetleme, firmalara bugünün dizaynı ile geleceğin maliyetlerinin düşürülmesinde ve kontrol edilmesinde yardımcı olmaktadır. Çalışmamızda, söz konusu maliyet sistemleri ayrıntıları ile incelenecektir.

  16. Marlin: Towards Seamless Content Sharing and Rights Management

    NARCIS (Netherlands)

    Keoh, S.L.

    2011-01-01

    Digital Rights Management (DRM) is used to protect copyrighted content from unauthorized use. However, it is still remains challenging to strike a balance between content sharing and rights management. Marlin is developing open standards for interoperable DRM technology.The Octopus and Nemo

  17. The relationship between amino acid and protein content of yellow ...

    African Journals Online (AJOL)

    feed industry are the relationships between isoleucine, leucine, lysine and arginine with crude protein content. Equations to predict the content of these amino acids from the amount of crude protein in maize are given. The remaining amino acids can be estimated without loss of accuracy from their mean value expressed as ...

  18. LHC? Of course we’ve heard of the LHC!

    CERN Multimedia

    2009-01-01

    Well, more or less. After its first outing in Meyrin (see last Bulletin issue), our street poll hits the streets of Divonne-les-Bains and the corridors of the University of Geneva. While many have heard of the LHC, the raison d’être of this "scientific whatsit" often remains a mystery.On first questioning, the "man-in-the-street" always pleads ignorance. "Lausanne Hockey Club?" The acronym LHC is not yet imprinted on people’s minds. "Erm, Left-Handed thingamajig?" But as soon as we mention the word "CERN", the accelerator pops straight into people’s minds. Variously referred to as "the circle" or "the ring", it makes you wonder whether people would have been so aware of the LHC if it had been shaped like a square. Size is another thing people remember: "It’s the world’s biggest. Up to now…" As for its purpose, well that’s another kettle of fish. &...

  19. Servikal nöral foraminal bölge ve uncinate çıkıntının embriolojik gelişimi ve anatomisinin klinikle ilişkilendirilmesi

    OpenAIRE

    BROHİ, Recep Ali

    2012-01-01

    Servikal bölge ile ilgili yapılan anatomik ve morfometrik çalışmaların büyük çoğunluğunda erişkin kadavra ve kemikleri kullanılmıştır. Servikal bölgenin ve bu bölge ile patolojilerde önemli rol oynayan uncinate proses ve servikal nöral foramen ile ilgili çalışmalar literatürde bulunsa da bu iki yapının embriolojik gelişimi yeterin...

  20. ERZURUM ŞARTLARINDA DİKİM ZAMANI VE TEPE ALMANIN PATATESTE VERİM VE ÇEŞİTLİ ÖZELLİKLERİNE ETKİSİ /

    OpenAIRE

    Şenol, Sabahattin

    2010-01-01

    ÖZETErzurum Ekolojik şartlarında dikim ve tepe alma zamanmm patatesteverime ve diğer bazı agronomik karekterlere etkisini tesbitetmek için bu çalışma yapılmış, erkenci ve geç olgunlaşan 34/962 ve49/962 çeşitler bu denemeye alınmıştır. Neticede, en fazıa verim enerken dikim zamanı olarak tayin ediıen 13 Mayıs tarihinde a.ltlnmış,tepe aımanm· veya sürgün öıdürmenin önemli etkisi g&ou...

    1. KENTSEL VE KOLEKTİF BELLEKTE KIRILMALAR VE KAMUSAL ALANIN DÖNÜŞÜMÜ: GİRNE ŞEHRİ LİMANI ÖRNEĞİ

      Directory of Open Access Journals (Sweden)

      Ümmü ALTAN BAYRAKTAR

      2015-09-01

      Full Text Available Özet Günümüzde modernleşme ve kapitalizm etkisinde, maddi, toplumsal ve bireysel yaşam büyük bir hız ve ölçekle değişmektedir. Yaşamlarımızın geçtiği mekanların da aynı hız ve ölçekle değişip dönüşmesi, insanların geçmiş ile bugün arasındaki dinamikleri daha fazla sor- gulamasına neden olmuştur. Bu da bellek ve mekan arasındaki ilişkiyi araştırmayı gündeme getirmiş; diğer çalışmaların yanında, kamusal alan olarak kentin ve kentselliğin sürdürülebil- mesini sağlayan kent merkezlerinin çok katmanlı tarihi dokusunun varlığı, geçirdiği değişim ve dönüşümü anlama çabalarını arttırmıştır. Günümüzde ekonomik rasyonalite mantığıy- la atılan adımlar sonucunda tarihsel-kültürel miras ve tarihsel kentsel dokular yitirilmeye başlanmıştır. Bu değişim ve dönüşüm kentsel ve kolektif bellekte kırılmalar yaşanmasına ve kamusal alanların yaşanan mekanlar olmaktan çıkmasına neden olmuştur. Kıbrıs’ın Girne Şehri’nde yer alan ‘Liman’, tarihsel süreç içerisindeki gelişimi, fiziki ve sosyal özellikleriyle kentsel ve kolektif bellekte varolan kırılmalar ve kamusal alanın dönüşümünde mekan ve iktidar açısından bu çalışma kapsamında ele alınmıştır. Çalışmanın kuramsal alt yapısı Jür- gen Habermas’ın Kamusal Alan ve Maurice Halbwachs’ın Kolektif Bellek kavramı üzerine kurulmaya çalışılmıştır.

    2. Afyon, Konya ve Eskişehir İllerinde Keçilerde Pestivirus ve Parainfluenzavirus Tip 3 Enfeksiyonlarının Serolojik Olarak Araştırılması

      OpenAIRE

      Gür, S; Erol, N; Yapıcı, O

      2014-01-01

      Bu çalışmada sağlıklı ve respiratorik-reprodüktif bozukluklar görülen keçi sürülerinde Pestivirus ve Parainfluenzavirus 3 (PI-3) enfeksiyonları serolojik olarak araştırıldı. Afyonkarahisar, Konya ve Eskişehir illerindeki 7 sürüden toplam 1346 kan örneği elde edildi. Mikronötralizasyon test sonucuna göre, sürü bazında pestivirus spesifik antikorların %35.2 ile %78.8 arasında değiştiği belirlenirken PI-3 için %17.5 ile %62 aralığında olduğu tespit edildi. Toplamda, 933 (%69.3) ve 584 (%43.3) ke...

    3. Data-driven remaining useful life prognosis techniques stochastic models, methods and applications

      CERN Document Server

      Si, Xiao-Sheng; Hu, Chang-Hua

      2017-01-01

      This book introduces data-driven remaining useful life prognosis techniques, and shows how to utilize the condition monitoring data to predict the remaining useful life of stochastic degrading systems and to schedule maintenance and logistics plans. It is also the first book that describes the basic data-driven remaining useful life prognosis theory systematically and in detail. The emphasis of the book is on the stochastic models, methods and applications employed in remaining useful life prognosis. It includes a wealth of degradation monitoring experiment data, practical prognosis methods for remaining useful life in various cases, and a series of applications incorporated into prognostic information in decision-making, such as maintenance-related decisions and ordering spare parts. It also highlights the latest advances in data-driven remaining useful life prognosis techniques, especially in the contexts of adaptive prognosis for linear stochastic degrading systems, nonlinear degradation modeling based pro...

    4. Factors stimulating content marketing

      Directory of Open Access Journals (Sweden)

      Naser Azad

      2016-02-01

      Full Text Available This paper presents an empirical investigation to determine factors influencing on content marketing in banking industry. The study designs a questionnaire consists of 40 questions in Likert scale and distributes it among 550 randomly selected regular customers of Bank Mellat in city of Tehran, Iran and 400 properly filled questionnaires are collected. Cronbach alphas for all components of the survey are well above desirable level. Using principle component analysis with Varimax rotation, the study has determined six factors influencing the most on content marketing including organization, details, having new ideas, quality, sensitivity and power while the last component contains only two subcomponents and is removed from the study.

    5. Photographs of conflicts: what remains? Fotografias de conflito: o que permanece?

      Directory of Open Access Journals (Sweden)

      Kátia Hallak Lombardi

      2011-12-01

      Full Text Available Images of pain and war are constantly published by the media, and ultimately generate a true “iconography of suffering.” This article proposes a discussion of other formats of photographic language that is distinct from the usual media production and conflicts that are related to Benjamin’s conception of the logic of the trace. What are the prospects of enlargement of the photographic language focused on the representation of war? The book Fait, Sophie Ristelhueber (2009, is taken to illustrate how photography can lead to new tensions. Resumo: Imagens da dor e da guerra são publicadas constantemente pelos veículos de comunicação, acabando por gerar uma verdadeira “iconografia do sofrimento”. Este artigo propõe a discussão sobre outros formatos de linguagem fotográfica que se diferenciem da produção midiática habitual de conflitos e que estejam relacionados à concepção benjaminiana da lógica do vestígio. Quais as possibilidades de alargamento da linguagem fotográfica voltada para a representação da guerra? O livro Fait, de Sophie Ristelhueber (2009, é tomado para exemplificar como a fotografia pode provocar novas tensões.

    6. The Naïve Utility Calculus: Computational Principles Underlying Commonsense Psychology.

      Science.gov (United States)

      Jara-Ettinger, Julian; Gweon, Hyowon; Schulz, Laura E; Tenenbaum, Joshua B

      2016-08-01

      We propose that human social cognition is structured around a basic understanding of ourselves and others as intuitive utility maximizers: from a young age, humans implicitly assume that agents choose goals and actions to maximize the rewards they expect to obtain relative to the costs they expect to incur. This 'naïve utility calculus' allows both children and adults observe the behavior of others and infer their beliefs and desires, their longer-term knowledge and preferences, and even their character: who is knowledgeable or competent, who is praiseworthy or blameworthy, who is friendly, indifferent, or an enemy. We review studies providing support for the naïve utility calculus, and we show how it captures much of the rich social reasoning humans engage in from infancy. Copyright © 2016 Elsevier Ltd. All rights reserved.

    7. Association between auditory P300, psychopathology, and memory function in drug-naïve schizophrenia.

      Science.gov (United States)

      Chang, Wei-Hung; Chen, Kao-Chin; Yang, Yen-Kuang; Chen, Po-See; Lu, Ru-Band; Yeh, Tzung-Lieh; Wang, Carol Sheei-Meei; Lee, I-Hui

      2014-03-01

      The aim of this study was to explore memory deficits and psychopathology and their relationships with P300 in drug-naïve patients with schizophrenia. The Positive and Negative Syndrome Scale (PANSS) and the Wechsler Memory Scale-Revised were administered. Auditory event-related potentials elicited by an oddball paradigm were obtained. After controlling for age, sex, the results showed a statistically significant negative correlation between the total PANSS score and P300 amplitude at the parietal position (r = -0.66, p visual memory was significantly positively correlated with P300 amplitude at the parietal position (r = 0.67, p memory decompensation in P300 among drug-naïve patients with schizophrenia may be considered, and the compensatory or Default Model Network might be a possible explanation of this association. Copyright © 2013. Published by Elsevier B.V.

    8. Postpartum depresyonda evlilik doyumu ve benlik saygısının incelenmesi

      OpenAIRE

      Karamustafa, Fatma Cansu

      2017-01-01

      Text in Turkish; Abstract: English and Turkish Includes bibliographical references (leaves: 79-90) xi, 103 leaves Amaç: Gebelik ve doğum sonrası kadınlarda fizyolojik, psikolojik ve sosyal açıdan değişimlerin meydana geldiği bir dönemdir. Kadınların birçoğu bu dönemdeki değişimlere sağlıklı bir baş etme stratejisi geliştirebilmesine rağmen her kadın için aynı durum söz konusu olmamaktadır. Doğum sonrası dönemde görülen rahatsızlıklardan biri de postpartum depresyondur. Doğumun yol aç...

    9. FREDERICK WINSLOW TAYLOR VE FİZYOLOJİK ÖRGÜT KURAMI

      OpenAIRE

      ASUNAKUTLU, Tuncer; COŞKUN, Bayram

      2005-01-01

      Bilimsel Yönetimin İlkeleri (The Principles of Scientific Management) adlı eserin yayınlanması yönetim tarihi açısından bir dönüm noktası kabul edilmektedir. Bilimsel anlamda yönetimi ilk kez ele alan ve analiz eden bu eser yayınlandığında çok önemli etkiler yaratmıştır. Bu eserin sahibi yönetim bilimi tarihinde önemli bir yeri olan F.W.Taylor’dur. Bu çalışma Taylor’un kişilik özellikleri ile geliştirdiği kuramı bütünsel olarak incelemek ve bu teorinin almış olduğu eleştirileri açıklamak amac...

    10. Kombucha ve Sağlık Üzerine Etkileri

      OpenAIRE

      İLERİ, Tülay; BÜYÜKOĞLU, -; TAŞÇI, Fulya; ŞAHİNDOKUYUCU, Fatma

      2014-01-01

      Kombucha, maya ve asetik asit bakterilerinin simbiyotik ilişkisi neticesi tatlandırılmış siyah çayın geleneksel fermentasyonudur. Sağlık üzerine muhtemel etkileri Kombucha’ya olan ilginin artmasına yol açmaktadır. Bu derlemede, biz Kombucha’nın bazı bileşenlerinin özelliklerine ışık tutan çalışmaları ortaya koyduk. Böylece, Kombucha’nın karmaşık mekanizmalarının daha iyi anlaşılması sağlanabilir ve sağlık üzerine Kombucha’nın etkileri hakkında yeni çalışmalar üretilebilir...

    11. Punica granatum L. Çekirdek ve Kabuk Ekstrelerinin Antioksidan Aktiviteleri

      OpenAIRE

      DEMİR, Hülya

      2008-01-01

      Bu çalışmada, Punica granatum L.(Punicaceae) "Nar", meyve çekirdeği ile kabuk ekstraklarının antioksidan aktiviteleri araştırıldı. Punica granatum L. çekirdek ve kabuğunun metanol ve hekzan ekstrelerinde serbest radikal giderme aktivite, indirgenme gücü analizleri yapıldı. Elde edilen sonuçlar standart antioksidan olarak bilinen askorbik asit ile karşılaştırıldı. Bu çalışmada elde edilen sonuçlara göre antioksidan aktivite Askorbik asit> Punica granatum L. kabuğu> Puni...

    12. Türkiye ve Dünyada Ayva Piyasası

      Directory of Open Access Journals (Sweden)

      Bekir Sıtkı Şirikçi

      2017-07-01

      Full Text Available Bu çalışmada dünyada ve Türkiye’de ayva piyasası irdelenmiştir. Çalışmada birincil verileri, ayva üretiminin yoğun olarak yapıldığı Sakarya, Antalya, Bursa, Bilecik ve Denizli illerinde farklı pazarlama seviyelerindeki 28 aracı işletme ile anket yöntemi ile elde edilen veriler oluşturmuştur. İkincil veriler ise FAO ve TÜİK gibi kurumlarının verilerinden hareketle elde edilmiştir. Dönem başlangıcı olan 1981-1985 ortalamasına göre 324465 ton olan dünya ayva üretimi %94,3 artışla 2013 yılında 630325 tona yükselmiştir. Dünya ayva üretiminde önemli ülkeler; Türkiye, Çin, Özbekistan, Fas ve İran’dır. Türkiye’de ayva üretimi, 1981-1985 ortalamasına göre 1.60 kat artmıştır. Ayva üretimindeki bu artışta ağaç başına verimdeki yükselmenin katkısı önemlidir (%40 verimde artış. Dünyada üretilen ayvanın %5,3’ü ihracata konu olmaktadır. Dünya ayva ihracat miktarı 8,32 kat, değeri ise 38,42 kat artmıştır. Ayva ihracat değerlerinde en yüksek paya Hollanda sahiptir (%33,6’sı. Hollanda’yı sırasıyla Türkiye, Avusturya ve İran takip etmektedir. Türkiye’nin dünya ihracat değerindeki payı ise %31,1’dir. Dünya ayva ithalatında %23,3 pay ile Rusya birinci sıradadır. Rusya’yı sırası ile Avusturya ve Almanya takip etmektedir. Türkiye’nin ayva üretiminin %9,4’ü ihracata konu olmaktadır. Önemli ayva üreticisi iller; Sakarya, Bursa, Antalya, Bilecik ve Denizli’dir. Görüşülen aracıların 15’i ayvada pazarlama aşamasında karşılaştıkları en önemli sorunun istenilen zaman, miktar, kalite ve fiyatta ayva bulunmamasını (%54 belirtmiştir.

    13. Temporal Lob Epilepsi'sinde L-Arginine ve CaEDTA'nın Etkileri

      OpenAIRE

      NOYAN, Behzat

      2005-01-01

      Bu çalışmada, bir nitrik oksit (NO-) prekürsörü olan L-Arginine ve bir ekstrasellüler çinko şelatörü olan CaEDTA'nın pilokarpine HCl ile oluşturulan kısa süreli epileptik nöbet üzerine etkileri araştırıldı. Deney, nöbet kontrol (serum fizyolojik 10 µl, i.c.v., ve sonra 380 mg/kg pilokarpine HCl i.p.), L-Arginine (150 µg/10 µl, i.c.v.), CaEDTA (100 mM, 10 µl, i.c.v.), L-Arginine+CaEDTA olmak üzere 4 gruptan oluştu. Enjeksiyonlardan sonra iki saat boyunca nöbet davranışları gözlemlenen ...

    14. Trustworthy content push

      OpenAIRE

      Kuntze, Nicolai; Schmidt, Andreas U.

      2006-01-01

      Delivery of content to mobile devices gains increasing importance in industrial environments to support employees in the field. An important application are e-mail push services like the fashionable Blackberry. These systems are facing security challenges regarding data transport to, and storage of the data on the end user equipment. The emerging Trusted Computing technology offers new answers to these open questions.

    15. LCS Content Document Application

      Science.gov (United States)

      Hochstadt, Jake

      2011-01-01

      My project at KSC during my spring 2011 internship was to develop a Ruby on Rails application to manage Content Documents..A Content Document is a collection of documents and information that describes what software is installed on a Launch Control System Computer. It's important for us to make sure the tools we use everyday are secure, up-to-date, and properly licensed. Previously, keeping track of the information was done by Excel and Word files between different personnel. The goal of the new application is to be able to manage and access the Content Documents through a single database backed web application. Our LCS team will benefit greatly with this app. Admin's will be able to login securely to keep track and update the software installed on each computer in a timely manner. We also included exportability such as attaching additional documents that can be downloaded from the web application. The finished application will ease the process of managing Content Documents while streamlining the procedure. Ruby on Rails is a very powerful programming language and I am grateful to have the opportunity to build this application.

    16. Tourist-created Content

      DEFF Research Database (Denmark)

      Munar, Ana Maria

      2011-01-01

      study of social media sites and destination brands, relying on qualitative research methods, content analysis and field research. Findings – Tourists are largely contributing to destination image formation, while avoiding the use of the formal elements of the brands. The most popular strategies used...

    17. Loser Generated Content

      DEFF Research Database (Denmark)

      Petersen, Søren Mørk

      2008-01-01

      In this article [ 1 ] some of the critical aspects of Web 2.0 are mapped in relation to labor and the production of user generated content. For many years the Internet was considered an apt technology for subversion of capitalism by the Italian post–Marxists. What we have witnessed, however...

    18. Türkiye'de Kadınla İlgili Kalkınma Politikalarının ve Projelerinin Eleştirel Bir Değerlendirmesi A Critical Evaluation of Gender Related Development Policy and Projects in Turkey

      Directory of Open Access Journals (Sweden)

      Gökhan GÖKULU

      2013-09-01

      Full Text Available In this study, how women are included in development policy,program and projects and the content of the gender equality policies ofpublic institutions will tried analyzed in relation with the theoriesregarding relationship of development and women and theinternationally accepted (by UN and EU gender values. The problem ofwomen’s development and ensuring gender equality in Turkey is onlybecome a issue after the agreement of CEDAW with UN and theintegration process of Turkey to EU. Even if the principles of increasingthe women’s socio-economic status, enhancing the gender equality andelimination of all discriminations against women are stated andpromised by the development plans and Genel Directorate of Women’sStatus, there are problems and ambiguities in the execution of theseprinciples. The primary reason for this is that the related principleswere not accepted yet by the related public institutions (central andlocal and their personal but only became an issue because of thecommitments of the state to EU and UN and the lack of long termpolicies to be designed to alter the socially accepted judgements thatprevent the equality of men and women. Instead of this, as it isobserved both in the projects of public institutions, and in the nongovermentalinstitutions, the activities carried out for sustainingwomen’s development and equal status with men is oriented topreparing and implying projects to increase women’s economic activitiesand contribute to family’s subsistence. In addition, for sustaining thesucesss of policies aiming gender equality and acceptance of thesepolicies by the targeted social groups, the participation of these targetedsocial groups to the policy making process as decision makers arerequired. Bu çalışma, Türkiye’deki kadınların kalkınma politika, program ve projelerine nasıl ve hangi biçimde dâhil olduklarını ve toplumsal cinsiyet eşitliğine dayalı kamusal politikaların içeriğini, kadınların kalk

    19. Ülkemizde Yetiştirilen Başlıca Buğday Çeşitlerinin ve Unlarının Tiamin ve Riboflavin Miktarları

      Directory of Open Access Journals (Sweden)

      Recai Ercan

      2015-02-01

      Full Text Available Bu çalışmada, ülkemizde yetiştirilen başlıca buğday çeşitlerinin ve bunların laboratuvar değirmeninde öğütülmesiyle elde edilen unlarının B1 ve B2 vitaminleri miktarı saptanmıştır. Araştırmada 18 buğday çeşidi kullanılmıştır. Buğdaylarda B1 ve B2 vitaminleri miktarı çeşit ve yetişme yerine bağlı olarak değişmektedir. Genellikle sert buğdaylar, yumuşaklardan daha zengin bulunmuştur. Unlarda B1 ve B2 vitamin miktarlarının buğday çeşidi ve randımanı ile ilişkili olduğu görülmüştür. Un randımanı arttıkça vitamin miktarları da artmaktadır.

    20. Duchenne Müsküler Distrofi ve Gilbert"s Sendromu Birlikteliği: Bir Olgu Sunumu

      OpenAIRE

      İncecik, Faruk; Hergüner, Özlem M.; Mert, Gülen; Horoz, Özden; Altunbaşak, Şakir

      2014-01-01

      Gilbert"s sendromu konjuge olmayan hiperbilirubinemi ile karekterize bir hastalıktır. 5 yaşında erkek çocuğu hafif sarılık ile hastanemize getirildi. Hastanın karaciğer enzimleri ve kreatin fosfokinaz yüksekliği ile beraber ısrarcı unkonjuge hiperbilirubinemisi vardı. Normal hemoglobin ve retikülosit değerleri ile hemoliz dışlandı ve Gilbert"s sendromu tanısı konuldu. Kreatin kinaz değeri 15600 U/l idi ve distrofin geninde delesyon mevcuttu. Sonuç olarak hastaya Gilbert"s sendr...

    1. Çeşitli kalsiyum boratların sentezi, karakterizasyonu ve alev geciktirici etkinliklerinin incelenmesi

      OpenAIRE

      DURĞUN, Zeynep Gülşah

      2010-01-01


        Türkiye sahip olduğu bor rezervleri ve cevherlerinin kalitesi ile dünyanın önde gelen ülkelerinden biri olmasına rağmen minerallerin çeşitliliği ve işlenebilirliği yetersizdir. Bu nedenle değişik endüstriyel uygulamalara yönelik sentetik bor bileşiklerinin elde edilmesi önemli bir ihtiyaçtır. Bilinen yaklaşık 230 çeşit bor bileşiği mevcuttur ve bir kalsiyum hekzaborat türevi olan Nobleit de bunlardan bir tanesidir. Yangınlarda can ve mal kaybın...

    2. GELECEĞİN FİNANSMAN TEKNİĞİ: BARTER ve MUHASEBELEŞTİRİLMESİ

      OpenAIRE

      ATABEY, N. Ata; YILMAZ, Baki

      2001-01-01

      Barter, ekonomik kriz dönemlerinde mal ve hizmetlerin takas yolu ile satıldığı ve satın alındığı bir pazarda paranın maliyetini en az düzeye indirmek için geliştirilmiş alternatif finansman tekniklerinden biridir. Barter sistemi, işletmelerde pazarlama, satınalma ve finansman fonksiyonlarını bir arada yürüten barter organizasyonları sayesinde gelişerek yaygınlaşmaktadır. Çalışmamızda barter tekniğinin tanıtılması, işleyişi ve muhasebeleştirilmesi üzerinde durulmuştur....

    3. Man kan ikke dumpe til folkeskolens afgangsprøve – eller kan man?

      DEFF Research Database (Denmark)

      Ejersbo, Lisser Rye

      2016-01-01

      Indførelse af karakterkravet 2 som adgangsgivende til de erhversfaglige uddannelser har forvandlet 9. klasses prøven i dansk og matematik til en ”high-stakes-eksamen”, altså en vind-eller-forsvind-prøve. Hvad betyder det for de elever, der ligger på grænsen? Og hvor ”sikker” er en sådan sortering...

    4. Induced pluripotent stem cells derived from rabbits exhibit some characteristics of naïve pluripotency

      Science.gov (United States)

      Osteil, Pierre; Tapponnier, Yann; Markossian, Suzy; Godet, Murielle; Schmaltz-Panneau, Barbara; Jouneau, Luc; Cabau, Cédric; Joly, Thierry; Blachère, Thierry; Gócza, Elen; Bernat, Agnieszka; Yerle, Martine; Acloque, Hervé; Hidot, Sullivan; Bosze, Zsuzsanna; Duranthon, Véronique; Savatier, Pierre; Afanassieff, Marielle

      2013-01-01

      Summary Not much is known about the molecular and functional features of pluripotent stem cells (PSCs) in rabbits. To address this, we derived and characterized 2 types of rabbit PSCs from the same breed of New Zealand White rabbits: 4 lines of embryonic stem cells (rbESCs), and 3 lines of induced PSCs (rbiPSCs) that were obtained by reprogramming adult skin fibroblasts. All cell lines required fibroblast growth factor 2 for their growth and proliferation. All rbESC lines showed molecular and functional properties typically associated with primed pluripotency. The cell cycle of rbESCs had a prolonged G1 phase and a DNA damage checkpoint before entry into the S phase, which are the 2 features typically associated with the somatic cell cycle. In contrast, the rbiPSC lines exhibited some characteristics of naïve pluripotency, including resistance to single-cell dissociation by trypsin, robust activity of the distal enhancer of the mouse Oct4 gene, and expression of naïve pluripotency-specific genes, as defined in rodents. According to gene expression profiles, rbiPSCs were closer to the rabbit inner cell mass (ICM) than rbESCs. Furthermore, rbiPSCs were capable of colonizing the ICM after aggregation with morulas. Therefore, we propose that rbiPSCs self-renew in an intermediate state between naïve and primed pluripotency, which represents a key step toward the generation of bona fide naïve PSC lines in rabbits. PMID:23789112

    5. The Electronic Sandtable: An Application of VE-Technology as Tactical Situation Display

      Science.gov (United States)

      2000-11-01

      plastic stereoscopic intelligibility of a complex tactical situation. The visualization of three-dimensional data. It has been situation scenario is not...generated artificial reality was mentioned first in science ergonomics and human factors is essential for the fiction literature at the middle of the...basically two different types of TSD’s VRML-Browsers and Videogames work like this. used by the strike forces. VE-systems are on their way of becoming

    6. Naïve Conceptions About Multimedia Learning:A Study on Primary School Textbooks

      OpenAIRE

      Barbara eColombo; Alessandro eAntonietti

      2013-01-01

      An interview study, based on specific pictures taken from textbooks used in primary schools, was carried out to investigate illustrators’, teachers’, students’, and common people’s beliefs about the role that illustrations play in facilitating learning. Participants’ responses were internally coherent, indicating a systematic nature of the underlying naïve conceptions. Findings disprove Mayer’s pessimistic claim that laypersons’ conceptions of multimedia learning fail to match experiment...

    7. Children’s conceptions of mental illness: A naïve theory approach.

      OpenAIRE

      Fox, C; Buchanan-Barrow, E; Barrett, MD

      2010-01-01

      This paper reports two studies that investigated children's conceptions of mental illness using a naïve theory approach, drawing upon a conceptual framework for analysing illness representations which distinguishes between the identity, causes, consequences, curability, and timeline of an illness. The studies utilized semi-structured interviewing and card selection tasks to assess 6- to 11-year-old children's conceptions of the causes and consequences (Study 1) and the curability and timeline...

    8. VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

      International Nuclear Information System (INIS)

      Fujisawa, Hiroshi; Nakajima, Nakako Izumi; Sunada, Shigeaki; Lee, Younghyun; Hirakawa, Hirokazu; Yajima, Hirohiko; Fujimori, Akira; Uesaka, Mitsuru; Okayasu, Ryuichi

      2015-01-01

      High linear energy transfer (LET) radiation such as carbon ion particles is successfully used for treatment of solid tumors. The reason why high LET radiation accomplishes greater tumor-killing than X-rays is still not completely understood. One factor would be the clustered or complex-type DNA damages. We previously reported that complex DNA double-strand breaks produced by high LET radiation enhanced DNA end resection, and this could lead to higher kinase activity of ATR protein recruited to RPA-coated single-stranded DNA. Although the effect of ATR inhibition on cells exposed to low LET gamma-rays has recently been reported, little is known regarding the effect of ATR inhibitor on cells treated with high LET radiation. The purpose of this study is to investigate the effects of the ATR inhibitor VE-821 in human tumor and normal cells irradiated with high LET carbon ions. HeLa, U2OS, and 1BR-hTERT (normal) cells were pre-treated with 1 μM VE-821 for 1 hour and irradiated with either high LET carbon ions or X-rays. Cell survival, cell cycle distribution, cell growth, and micronuclei formation were evaluated. VE-821 caused abrogation of G2/M checkpoint and forced irradiated cells to divide into daughter cells. We also found that carbon ions caused a higher number of multiple micronuclei than X-rays, leading to decreased cell survival in tumor cells when treated with VE-821, while the survival of irradiated normal cells were not significantly affected by this inhibitor. ATR inhibitor would be an effective tumor radiosensitizer with carbon ion irradiation. The online version of this article (doi:10.1186/s13014-015-0464-y) contains supplementary material, which is available to authorized users

    9. Taoistický pohled na trénování ve fotbalu a triatlonu

      OpenAIRE

      Skála, Tomáš

      2009-01-01

      Nazev: Taoisticky pohled na trenovani ve fotbalu a triatlonu Cile prace: Objasnit pojmy taoismus a Tao, pomoci jejich charakteristiky osvetlit taoisticke vnimani sebe sama, okolniho sveta a pohybove aktivity, s naslednou aplikaci na konkretni sporty fotbal a triatlon. Metody: Deskripce, analyza, spekulace Klicova slova: Taoismus, Tao, Cchi, Jin a Jang, Wu-Wej, fotbal, triatlon, zacatecnicka mysl SUMMARY Title: The taoistic view in the football and triatlon training Objective: To explain terms...

    10. Alterations of Intrinsic Connectivity Networks in Antipsychotic-Naïve First-Episode Schizophrenia

      DEFF Research Database (Denmark)

      Anhøj, Simon; Ødegaard Nielsen, Mette; Jensen, Maria Høj

      2018-01-01

      Background: The investigation of large-scale intrinsic connectivity networks in antipsychotic-naïve first-episode schizophrenia increases our understanding of system-level cerebral dysfunction in schizophrenia while enabling control of confounding effects of medication and disease progression. Re......-parietal networks suggested to be involved in the control of cognitive and sensory functions. Moreover, the present study suggests that the problem of not disengaging the VAN leads to difficulties with attention and possibly subjective awareness....

    11. Naïve realism: folk fallacies in the design and use of visual displays.

      Science.gov (United States)

      Smallman, Harvey S; Cook, Maia B

      2011-07-01

      Often implicit in visual display design and development is a gold standard of photorealism. By approximating direct perception, photorealism appeals to users and designers by being both attractive and apparently effortless. The vexing result from numerous performance evaluations, though, is that increasing realism often impairs performance. Smallman and St. John (2005) labeled misplaced faith in realistic information display Naïve Realism and theorized it resulted from a triplet of folk fallacies about perception. Here, we illustrate issues associated with the wider trend towards realism by focusing on a specific current trend for high-fidelity perspective view (3D) geospatial displays. In two experiments, we validated Naïve Realism for different terrain understanding tasks, explored whether certain individuals are particularly prone to Naïve Realism, and determined the ability of task feedback to mitigate Naïve Realism. Performance was measured for laying and judging a concealed route across realistic terrain shown in different display formats. Task feedback was either implicit, in Experiment 1, or explicit in Experiment 2. Prospective and retrospective intuitions about the best display formats for the tasks were recorded and then related to task performance and participant spatial ability. Participants generally intuited they would perform tasks better with more realism than they actually required. For example, counter to intuitions, lowering fidelity of the terrain display revealed the gross scene layout needed to lay a well-concealed route. Individuals of high spatial ability calibrated their intuitions with only implicit task feedback, whereas those of low spatial ability required salient, explicit feedback to calibrate their intuitions about display realism. Results are discussed in the wider context of applying perceptual science to display design, and combating folk fallacies. Copyright © 2010 Cognitive Science Society, Inc.

    12. Are delusional contents replayed during dreams?

      Science.gov (United States)

      D'Agostino, Armando; Aletti, Giacomo; Carboni, Martina; Cavallotti, Simone; Limosani, Ivan; Manzone, Marialaura; Scarone, Silvio

      2013-09-01

      The relationship between dream content and waking life experiences remains difficult to decipher. However, some neurobiological findings suggest that dreaming can, at least in part, be considered epiphenomenal to ongoing memory consolidation processes in sleep. Both abnormalities in sleep architecture and impairment in memory consolidation mechanisms are thought to be involved in the development of psychosis. The objective of this study was to assess the continuity between delusional contents and dreams in acutely psychotic patients. Ten patients with a single fixed and recurring delusional content were asked to report their dreams during an acute psychotic break. Sixteen judges with four different levels of acquaintance to the specific content of the patients' delusions were asked to group the dreams, expecting that fragments of the delusional thought would guide the task. A mathematical index (f,t) was developed in order to compare correct groupings between the four groups of judges. Most judges grouped the dreams slightly above chance level and no relevant differences could be found between the four groups [F(3,12)=1.297; p=n.s.]. Scoring of dreams for specific delusional themes suggested a continuity in terms of dream and waking mentation for two contents (Grandiosity and Religion). These findings seem to suggest that at least some delusional contents recur within patients' dreams. Future studies will need to determine whether such continuity reflects ongoing consolidation processes that are relevant to current theories of delusion formation and stabilization. Copyright © 2013 Elsevier Inc. All rights reserved.

    13. Doğu Karadeniz Bölgesinde Üretilen Balların Kimyasal ve Duyusal Nitelikleri

      Directory of Open Access Journals (Sweden)

      Zehra Güler

      2015-02-01

      Full Text Available Bal, başlıca karbonhidrat (glikoz ve früktoz ve sudan oluşan doğal bir üründür. Bu bileşenlerin yanı sıra protein, enzimler, organik asitler, mineral maddeler ve polen de içermektedir. Bal bileşimini ve özellikle de duyusal niteliğini üretildiği bölgenin florası önemli düzeyde etkilemektedir. Bu nedenle çalışmamız farklı florası ile bilinen Karadeniz bölgesinde (özellikle Hemşin üretilen ballar üzerinde gerçekleştirilmiştir. Üç yıl süresince her yıl Ağustos ayının son haftasında 10 adet bal örneği alınarak toplam 30 adet balın kimyasal ve duyusal nitelikleri incelenmiştir. Ballarda rutubet, invert şeker, sakkaroz, hidroksi metil furfural ve pH gibi nitelikler ortalama olarak sırasıyla % 18,90; % 68,42; % 1,54; 3,83 mg/kg ve 4,96 belirlenmiş ve yalnızca 1 örnekte ticari glikoz varlığına rastlanmıştır. Duyusal nitelikler bakımından ballar, açık sarı renkten-kahverengi ya da kahverengi-kırmızı renge, tat ve kokusu ise yavan bir aroma ve tat'dan çiçek kokusu, tatlı ve kinin acılığı benzeri bir tada kadar değişim göstermiştir. Elde edilen sonuçlara göre, bal örnekleri arasında kimyasal niteliklerin büyük farklılıklar göstermediği ancak duyusal bakımından belirgin bir değişim ortaya koydukları belirlenmiştir.

    14. Usûlî Kıyasın Bilgi ve Amel Değeri

      Directory of Open Access Journals (Sweden)

      Yrd.Doç.Dr. Temel Kacır

      2016-06-01

      Full Text Available “Ortak bir illete sahip olmaları nedeniyle, aslın hükmünün fer‘e verilmesidir" şeklinde tanımlanan usûlî kıyasın bilgi ve amel değeri, ilk dönemden itibaren tartışma konusu olmuştur. Şöyle ki; hüküm verme yetkisi sadece Şar‘î’e ait olduğu halde usûlî kıyasın dinde hüküm verme anlamına geldiği ve bilgi değerinin de nasslarca yerilmiş zan olduğu gibi bazı argümanlar ileri sürerek usûlî kıyası reddedenler olsa da, çoğunluk tarafından usûlî kıyas aslî ve şer‘î delil olarak kabul edilmiş ve elde edilen bu hüküm ile amel edilmesi gerekli görülmüştür. Bu çalışma, usûlî kıyası kabul eden ve etmeyenlerin görüşlerini mukayese etmenin ötesinde, usûlî kıyasın salt aklî bir çaba olmadığını, kendisi ile ulaşılan bilginin naslarda yerilen zan olmayıp aksine delile dayalı zannın en üst derecesi olduğunu ve bunun da furû fıkıhta amel için yeterli olduğunu naklî ve aklî deliller ile ele alan bir çalışmadır. Kıyasla ilgili genel bir çerçeve çizildikten sonra, usûlî kıyas ve deliller hiyerarşisindeki yeri ve kıyasın bilgi ve amelî değeri ile sınırlandırılan bu makale ile usûlî kıyasın bilgi ve amel değeri konusundaki tartışmalara açıklık getirilmek istenmektedir.

    15. XIII.Yüzyılda Eyyubiler, Memlükler ve Latin Doğu

      Directory of Open Access Journals (Sweden)

      R. Stephen HUMPREYS

      2007-06-01

      Full Text Available Müslüman yöneticiler ve güney batı Asya halkları arasında, kendi aralarında yaşayan (protoemperyalist veya kafir gibi betimlemeleri bulunan Haçlılara karşı koyma ve onları defetme miti baş­ langıçtan beri mevcuttu.

    16. Çocuk Diş Hekimliğinde Oral ve İntranazal Yollarla Orta Dereceli Sedasyon

      NARCIS (Netherlands)

      Özen, B.

      2013-01-01

      Çocuk Diş Hekimliğinde Oral ve İntranazal Yollarla Orta Dereceli Sedasyon Çocuk diş hekimliğinde korkulu, kaygılı ve uyumsuz hastaların tedavileri, midazolam gibi spesifik ilaçların oral veya intranazal yolla kullanılmıyla, sedasyon yönergelerine uyan hekimler tarafından orta dereceli sedasyon

    17. Enzimatik Yöntemle Bazı Sebze ve Meyvelerde Nitrat Düzeyinin Belirlenmesi

      Directory of Open Access Journals (Sweden)

      Nevzat Artık

      2015-02-01

      Full Text Available Bu çalışmada Ankara ve çevresinde 2000 yılı içerisinde yetiştirilen bazı taze sebze ve meyve örnekleri materyal olarak kullanıldı. Bu örneklere ait nitrat miktarları enzimatik Boehringer Mannheim GmbH metodu ile belirlendi. Nitrat içeriğinin taze sebzelerde 0.00-3019.41 mg/kg, taze meyvelerde ise 0.00-126.19 mg/kg arasında değiştiği saptandı. Nitrat miktarı, kereviz (3667.40 mg/kg, roka (3019,41 mg/kg ve pazı (2621.79 mg/kg örneklerinde yüksek bulunurken, kavun (0.00-47.93 mg/kgt karpuz (47.21-126.19 mg/kg gibi meyveler ile havuç (0.00-47.71 mg/kg, domates (0.00-71.10 mg/kg gibi meyve benzeri sebzelerde düşük düzeyde bulundu.

    18. Maternal ve fetal MBL2 genotiplerinin preterm doğumlarla ilişkisi

      OpenAIRE

      Taneri, Ayşe

      2009-01-01

      Yenidoğan döneminde, immün sistemin tam olarak gelismemesine bağlı karsılasılan komplikasyonlara ek olarak, yenidoğanın “prematüre” olması prenatal mortalite ve morbidite hızını arttıran baslıca faktördür. Görülme sıklığının %9 olması nedeni ile, günümüz perinatal tıbbının çözmeye çalıstığı ve çevresel, tıbbi ve kalıtsal faktörlerin rol oynadığı çoklu değisimlere bağlı bir yenidoğan sorunudur. Patogenezi aydınlatmaya yönelik yapılan çalısmalarda inflamasyonun gestasyonel sür...

    19. El’ Lisickij grafico costruttivista. La rivista “Vešč’-Gegenstand-Objet”

      Directory of Open Access Journals (Sweden)

      Alice Bravin

      2016-02-01

      Full Text Available This paper analyzes the graphic design of the international art journal “Vešč’-Gegenstand-Objet”, published in Berlin in 1922 by the Russian architect, painter, photographer and designer Lazar’ Markovič Lisickij (1890-1941, better known as El’ Lisickij, together with the Russian writer Il’ja Grigor’evič Èrenburg (1891-1967.Although it lasted only three issues (issues one and two were combined in a single volume which appeared in March/April 1922, while the last number appeared in May 1922, “Vešč’” had a strong influence on contemporary art. It was published in German, French and Russian and was meant both as a bridge between Russia and Europe after the years of war and revolution and as a symbol of the beginning of a new creative era. Mainly focusing on new Suprematist and Constructivist works, the journal included essays on several fields of art such as literature, cinema, theatre, painting, sculpture, architecture and music.In this paper I focus on the innovative graphic design of the two volumes of “Vešč’” entirely realized by El’ Lisickij. Referring to his own theories about book design, Lisickij created a functional and innovative layout and a striking cover, challenging the traditional graphic design practice by using exclusively standard typographic elements such as punctuation marks, typographic lines, geometric forms and typesetting.

    20. Nigral dopaminergic neuron replenishment in adult mice through VE-cadherin-expressing neural progenitor cells

      Directory of Open Access Journals (Sweden)

      Abir A Rahman

      2017-01-01

      Full Text Available The function of dopaminergic neurons in the substantia nigra is of central importance to the coordination of movement by the brain's basal ganglia circuitry. This is evidenced by the loss of these neurons, resulting in the cardinal motor deficits associated with Parkinson's disease. In order to fully understand the physiology of these key neurons and develop potential therapies for their loss, it is essential to determine if and how dopaminergic neurons are replenished in the adult brain. Recent work has presented evidence for adult neurogenesis of these neurons by Nestin+/Sox2– neural progenitor cells. We sought to further validate this finding and explore a potential atypical origin for these progenitor cells. Since neural progenitor cells have a proximal association with the vasculature of the brain and subsets of endothelial cells are Nestin+, we hypothesized that dopaminergic neural progenitors might share a common cell lineage. Therefore, we employed a VE-cadherin promoter-driven CREERT2:THlox/THlox transgenic mouse line to ablate the tyrosine hydroxylase gene from endothelial cells in adult animals. After 26 weeks, but not 13 weeks, following the genetic blockade of tyrosine hydroxylase expression in VE-cadherin+ cells, we observed a significant reduction in tyrosine hydroxylase+ neurons in the substantia nigra. The results from this genetic lineage tracing study suggest that dopaminergic neurons are replenished in adult mice by a VE-cadherin+ progenitor cell population potentially arising from an endothelial lineage.

    1. AHMET RIZA’NIN SOSYOLOJİK VE DİNİ GÖRÜŞLERİ

      OpenAIRE

      SARI, Süleyman Arif

      2004-01-01

      Bu tez giriş ve üç bölümden oluşmaktadır. Türkiye’de Pozitivizm akımının öncüsü durumunda olan Ahmet Rıza Bey, ülkeye pozitivist zihniyetin girmesini isterken, dinin sosyal içerikli konularına getirdiği değişik yorumlar ile Türk aydınlarının düşünce ufkunda ve sisteminde farklı bir yol açmıştır. Açtığı bu yol, bazı düşünce kalıpları içerisinde günümüzde de etkisini sürdürmektedir. Giriş bölümünde tezin konusu, amacı, önemi ve yöntemi ortaya konmuştur. Birinci bölümde din sosy...

    2. Les bibliothèques à Genève essai de chronologie : 1478-2013

      CERN Document Server

      Jacquesson, Alain

      2014-01-01

      Genève a toujours bénéficié, dans les bibliothèques publiques comme dans les fonds privés, de collections imprimées abondantes et remarquables. Le botaniste, historien des sciences et précurseur de la scientométrie Alphonse de Candolle, écrit en 1873 que « les cantons suisses de Genève, Vaud et Neuchâtel achètent plus de livres et de journaux sur les sciences que les populations vingt fois plus nombreuses des pays adjacents ». La vie intellectuelle du 21e siècle est évidemment différente, mais la qualité et la quantité des publications conservées à Genève restent toujours impressionnantes. Les quelques tableaux figurant en fin de cet ouvrage, inédits jusqu’ici, devraient stimuler toute personne intéressée par cet aspect de la culture. En effet, notre cité possède plus de 10 millions de documents imprimés. Il s’agit là d’une richesse remarquable. Ces collections couvrent une très grande partie du savoir humain et s’étendent des origines de l’imprimerie jusqu’aux publ...

    3. Mobil reklamlar ve mobil reklam araçlarına yönelik tutumlar

      OpenAIRE

      Barutçu, Süleyman; Öztürk Göl, Meltem

      2009-01-01

      Bu çalışmanın amacı, pazarlama bölümü yöneticilerinin dikkatlerini mobil iletişim teknolojilerindeki gelişmelerin sonucu olarak ortaya çıkan mobil pazarlama ve mobil reklam uygulamalarına çekmektir. Çalışmanın kavramsal analiz bölümünde mobil pazarlama, mobil reklamların önemi açıklanmış ve mobil reklam araçları (SMS, MMS ve Bluetooth Reklamları) analiz edilmiştir. Araştırma bölümünde ise mobil telefon kullanıcılarının mobil reklam araçlarına yönelik tutumlarının karşılaştırmalı olarak belirl...

    4. Outreaching particle physics to Latin America: CEVALE2VE and the use of ATLAS open data

      CERN Document Server

      Camacho Toro, Reina; The ATLAS collaboration

      2017-01-01

      Particle physics outreach can play a key role in promoting scientific culture and in the modernisation of university education in Latin America. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías in Spanish) builds collaborative networks with and between Latin American institutions and motivates physics undergraduate and master students to consider a career in scientific research by introducing them to cutting-edge research and tools used in High Energy Physics (HEP). The ATLAS open data project has been fundamental to achieve these goals as one of our main educational tools. As part of its commitment to open access and public engagement the ATLAS experiment has made available a large dataset to the public for the first time in 2016 and CEVALE2VE have been using this dataset for HEP virtual courses and Physics Without Frontiers roadshows. In this contribution we will present the different activities hosted by CEVALE2VE and discuss the importance of using open data an...

    5. Kesinleşen Tarih ve Yeni Bir Ad / History Made Certain and New Name

      OpenAIRE

      YURTTAŞ, Hüseyin; KINDIĞILI, Muhammed Lütfü

      2018-01-01

      Ö Z E TCimcime Hatun adı ile bilinen yapı, Erzurum şehir surları içerisindebulunmaktadır. Cumhuriyet Caddesi üzerindeki kümbet, Ulu Cami’ninkuzeybatısına düşmektedir. Yapının etrafını saran dükkân ve evlerin yıkılmasıylaşimdiye kadar bilinmeyen giriş kapısı ortaya çıkarılmıştır. Kümbetin kapıaçıklığının iç üç yanında yer alan ve atkı taşı hizasındaki iki satırlık yazıt, mezaranıtının kime ait olduğunun anlaşılması ve yapılış tarihini vermesiyle önemlidir.Kitabede tarih kısmı 704 H./1304 M. ol...

    6. Zeka, Öğrenme ve Düşünme

      Directory of Open Access Journals (Sweden)

      Emel Topçu

      2015-11-01

      Full Text Available Sokrates'ten bu yana huzurlu bir toplum için insanların eğitilmeleri ve liyakatlarına göre sınıflandırılmaları gerektiğine dair bir düşünce çeşitli versiyonları ile günümüze kadar gelmiştir. Daha sonraları en üst kategoride yer alan sınıfın üstünlüğünü ispat için çeşitli adlarla bilimsel çalışmalar denenmiştir. Modern çağın genellemeci alışkanlığı zekayı ve öğrenme yollarını da tek tipe indirgemektedir. ancak on dönemlerde inan zekaı ile ilgili çalışmalarla çoklu zeka anlayışı ortaya çıkmış, bu anlayışla birlikte öğrenme yolları da çeşitlenmiştir. Makalede çoklu zeka ve öğrenme yolları arasındaki ilişki incelenmektedir.

    7. İbrahim Müteferrika ve İlk Türk Matbaası

      Directory of Open Access Journals (Sweden)

      Şerif Korkmaz

      2015-11-01

      Full Text Available Osmanlı devletinin Avrupa'dan bilinçli iktibasların yapıldığı ilk dönem 1718-1730 yılları arasındaki "Lale Devri" dir. bu dönemde özellikle eğitimlerini incelemek için Avrupa'nın pek çok ülkesine elçiler gönderilmiştir. Fakat bu devrin en büyük ve en tesirli yeniliği İbrahim Müteferrika ve Sadi Efendi'nin birlikte açtıkları matbaadır. Makalede İbrahim Müteferrikanın kimliği ve fikirleri hakkında bilgi verilmektedir. Onun etkisinin sadece  matbaa ile sınırlı olmadığı, Osmanlı için yeni sayılabilecek ilimlerle ilgili eserleri basarak Avrupa'nın Rönesans'ından ilk haberleri verdiği vurgulanmaktadır.

    8. Career Motivation in Newly Licensed Registered Nurses: What Makes Them Remain

      Science.gov (United States)

      Banks, Zarata Mann; Bailey, Jessica H.

      2010-01-01

      Despite vast research on newly licensed registered nurses (RNs), we don't know why some newly licensed registered nurses remain in their current jobs and others leave the nursing profession early in their career. Job satisfaction, the most significant factor emerging from the literature, plays a significant role in nurses' decisions to remain in…

    9. Stable isotopes, niche partitioning and the paucity of elasmosaur remains in the Maastrichtian type area

      NARCIS (Netherlands)

      Schulp, Anne S.; Janssen, Renée; Van Baal, Remy R.; Jagt, John W M; Mulder, Eric W A; Vonhof, Hubert B.

      2017-01-01

      Remains of elasmosaurid plesiosaurs are exceedingly rare in the type-Maastrichtian strata (Late Cretaceous, southeast Netherlands and northeast Belgium), in stark contrast to relatively common skeletal remains of mosasaurs. Here, we present an analysis of δ13C stable isotope values for tooth enamel

    10. 20 CFR 408.330 - How long will your application remain in effect?

      Science.gov (United States)

      2010-04-01

      ... effect? 408.330 Section 408.330 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Filing Applications Filing Your Application § 408.330 How long will your application remain in effect? Your application for SVB will remain in effect from the date it is filed until...

    11. Carbohydrate Content in the GDM Diet: Two Views: View 2: Low-Carbohydrate Diets Should Remain the Initial Therapy for Gestational Diabetes

      OpenAIRE

      Mulla, Wadia R.

      2016-01-01

      IN BRIEF The appropriate dietary intervention for gestational diabetes mellitus (GDM) is not clear. Traditionally, a low-carbohydrate diet has been prescribed. Recently, there has been a movement to prescribe a diet higher in nutrient-dense carbohydrate as the initial treatment for GDM. At this time, there is insufficient outcome data to support this type of diet.

    12. Assessing various Infrared (IR) microscopic imaging techniques for post-mortem interval evaluation of human skeletal remains

      Science.gov (United States)

      Roider, Clemens; Ritsch-Marte, Monika; Pemberger, Nadin; Cemper-Kiesslich, Jan; Hatzer-Grubwieser, Petra; Parson, Walther; Pallua, Johannes Dominikus

      2017-01-01

      Due to the influence of many environmental processes, a precise determination of the post-mortem interval (PMI) of skeletal remains is known to be very complicated. Although methods for the investigation of the PMI exist, there still remains much room for improvement. In this study the applicability of infrared (IR) microscopic imaging techniques such as reflection-, ATR- and Raman- microscopic imaging for the estimation of the PMI of human skeletal remains was tested. PMI specific features were identified and visualized by overlaying IR imaging data with morphological tissue structures obtained using light microscopy to differentiate between forensic and archaeological bone samples. ATR and reflection spectra revealed that a more prominent peak at 1042 cm-1 (an indicator for bone mineralization) was observable in archeological bone material when compared with forensic samples. Moreover, in the case of the archaeological bone material, a reduction in the levels of phospholipids, proteins, nucleic acid sugars, complex carbohydrates as well as amorphous or fully hydrated sugars was detectable at (reciprocal wavelengths/energies) between 3000 cm-1 to 2800 cm-1. Raman spectra illustrated a similar picture with less ν2PO43−at 450 cm-1 and ν4PO43− from 590 cm-1 to 584 cm-1, amide III at 1272 cm-1 and protein CH2 deformation at 1446 cm-1 in archeological bone material/samples/sources. A semi-quantitative determination of various distributions of biomolecules by chemi-maps of reflection- and ATR- methods revealed that there were less carbohydrates and complex carbohydrates as well as amorphous or fully hydrated sugars in archaeological samples compared with forensic bone samples. Raman- microscopic imaging data showed a reduction in B-type carbonate and protein α-helices after a PMI of 3 years. The calculated mineral content ratio and the organic to mineral ratio displayed that the mineral content ratio increases, while the organic to mineral ratio decreases with

    13. Assessing various Infrared (IR microscopic imaging techniques for post-mortem interval evaluation of human skeletal remains.

      Directory of Open Access Journals (Sweden)

      Claudia Woess

      Full Text Available Due to the influence of many environmental processes, a precise determination of the post-mortem interval (PMI of skeletal remains is known to be very complicated. Although methods for the investigation of the PMI exist, there still remains much room for improvement. In this study the applicability of infrared (IR microscopic imaging techniques such as reflection-, ATR- and Raman- microscopic imaging for the estimation of the PMI of human skeletal remains was tested. PMI specific features were identified and visualized by overlaying IR imaging data with morphological tissue structures obtained using light microscopy to differentiate between forensic and archaeological bone samples. ATR and reflection spectra revealed that a more prominent peak at 1042 cm-1 (an indicator for bone mineralization was observable in archeological bone material when compared with forensic samples. Moreover, in the case of the archaeological bone material, a reduction in the levels of phospholipids, proteins, nucleic acid sugars, complex carbohydrates as well as amorphous or fully hydrated sugars was detectable at (reciprocal wavelengths/energies between 3000 cm-1 to 2800 cm-1. Raman spectra illustrated a similar picture with less ν2PO43-at 450 cm-1 and ν4PO43- from 590 cm-1 to 584 cm-1, amide III at 1272 cm-1 and protein CH2 deformation at 1446 cm-1 in archeological bone material/samples/sources. A semi-quantitative determination of various distributions of biomolecules by chemi-maps of reflection- and ATR- methods revealed that there were less carbohydrates and complex carbohydrates as well as amorphous or fully hydrated sugars in archaeological samples compared with forensic bone samples. Raman- microscopic imaging data showed a reduction in B-type carbonate and protein α-helices after a PMI of 3 years. The calculated mineral content ratio and the organic to mineral ratio displayed that the mineral content ratio increases, while the organic to mineral ratio

    14. Assessing various Infrared (IR) microscopic imaging techniques for post-mortem interval evaluation of human skeletal remains.

      Science.gov (United States)

      Woess, Claudia; Unterberger, Seraphin Hubert; Roider, Clemens; Ritsch-Marte, Monika; Pemberger, Nadin; Cemper-Kiesslich, Jan; Hatzer-Grubwieser, Petra; Parson, Walther; Pallua, Johannes Dominikus

      2017-01-01

      Due to the influence of many environmental processes, a precise determination of the post-mortem interval (PMI) of skeletal remains is known to be very complicated. Although methods for the investigation of the PMI exist, there still remains much room for improvement. In this study the applicability of infrared (IR) microscopic imaging techniques such as reflection-, ATR- and Raman- microscopic imaging for the estimation of the PMI of human skeletal remains was tested. PMI specific features were identified and visualized by overlaying IR imaging data with morphological tissue structures obtained using light microscopy to differentiate between forensic and archaeological bone samples. ATR and reflection spectra revealed that a more prominent peak at 1042 cm-1 (an indicator for bone mineralization) was observable in archeological bone material when compared with forensic samples. Moreover, in the case of the archaeological bone material, a reduction in the levels of phospholipids, proteins, nucleic acid sugars, complex carbohydrates as well as amorphous or fully hydrated sugars was detectable at (reciprocal wavelengths/energies) between 3000 cm-1 to 2800 cm-1. Raman spectra illustrated a similar picture with less ν2PO43-at 450 cm-1 and ν4PO43- from 590 cm-1 to 584 cm-1, amide III at 1272 cm-1 and protein CH2 deformation at 1446 cm-1 in archeological bone material/samples/sources. A semi-quantitative determination of various distributions of biomolecules by chemi-maps of reflection- and ATR- methods revealed that there were less carbohydrates and complex carbohydrates as well as amorphous or fully hydrated sugars in archaeological samples compared with forensic bone samples. Raman- microscopic imaging data showed a reduction in B-type carbonate and protein α-helices after a PMI of 3 years. The calculated mineral content ratio and the organic to mineral ratio displayed that the mineral content ratio increases, while the organic to mineral ratio decreases with time

    15. OPINIONS OF PRIMARY EDUCATION SEVENTH GRADE STUDENTS ABOUT TEACHING OF HISTORY TOPICS IN SOCIAL SCIENCES AND SIGNIFICANCE OF HISTORY İLKÖĞRETİM YEDİNCİ SINIF ÖĞRENCİLERİNİN SOSYAL BİLGİLER DERSLERİNDE TARİH KONULARININ İŞLENİŞİ VE TARİHİN DEĞERİ İLE İLGİLİ GÖRÜŞLERİ

      Directory of Open Access Journals (Sweden)

      Ramazan KAYA

      2012-06-01

      Full Text Available This study aims at determining primary education seventh grade students’ opinions on teaching of history topics in social science cources and significance of history in their lives. The population of the study comprises of 20 pieces seventh grade classes in 4 primary schools with medium socio-economic levels in the city center of Erzurum. As the sample of the study, a total of 200 students (10 students from each class were chosen via random sampling from seventh grade classes of these schools according to the appropriate sampling method. Required data for this qualitative research was acquired by a 4-item questionnaire comprising of open-ended questions. Content analysis method was adopted in analysis of the obtained data in this study. Findings shows that methods in line with constructivist approach remain limited in teaching of the topics; students like methods in which they are more active; such as drama and acting they like learning history, and, in general, they think that learning history makes a great contribution to their lives. Bu araştırmanın amacı, İlköğretim yedinci sınıf öğrencilerinin sosyal bilgiler dersinde tarih konularının işlenişi ve tarihin yaşamlarındaki değeri ile ilgili görüşlerini tespit edebilmektir.Araştırmanın evrenini, Erzurum merkezde sosyo-ekonomik bakımdan orta düzeyde 4 ilköğretim okulundaki toplam 20 tane yedinci sınıf şubesi oluşturmaktadır. Örneklem olarak uygun örnekleme yöntemine göre seçilen bu okulların yedinci sınıflarından tesadüfî örneklem yoluyla her sınıftan 10’ar öğrenci olmak üzere toplam 200 öğrenci seçilmiştir. Nitel araştırma yöntemi ile gerçekleştirilen bu araştırma için gerekli olan veriler, 4 adet açık uçlu sorudan oluşan bir anket vasıtasıyla edinilmiştir. Araştırma sonucunda elde edilen verilerin çözümlenmesinde içerik analizi yöntemi benimsenmiştir. Elde edilen bulgulara göre derslerin işlenişinde yap

    16. Screw Remaining Life Prediction Based on Quantum Genetic Algorithm and Support Vector Machine

      Directory of Open Access Journals (Sweden)

      Xiaochen Zhang

      2017-01-01

      Full Text Available To predict the remaining life of ball screw, a screw remaining life prediction method based on quantum genetic algorithm (QGA and support vector machine (SVM is proposed. A screw accelerated test bench is introduced. Accelerometers are installed to monitor the performance degradation of ball screw. Combined with wavelet packet decomposition and isometric mapping (Isomap, the sensitive feature vectors are obtained and stored in database. Meanwhile, the sensitive feature vectors are randomly chosen from the database and constitute training samples and testing samples. Then the optimal kernel function parameter and penalty factor of SVM are searched with the method of QGA. Finally, the training samples are used to train optimized SVM while testing samples are adopted to test the prediction accuracy of the trained SVM so the screw remaining life prediction model can be got. The experiment results show that the screw remaining life prediction model could effectively predict screw remaining life.

    17. "SINCE I MUST PLEASE THOSE BELOW": HUMAN SKELETAL REMAINS RESEARCH AND THE LAW.

      Science.gov (United States)

      Holland, Thomas D

      2015-01-01

      The ethics of non-invasive scientific research on human skeletal remains are poorly articulated and lack a single, definitive analogue in western law. Laws governing invasive research on human fleshed remains, as well as bio-ethical principles established for research on living subjects, provide effective models for the establishment of ethical guidelines for non-invasive research on human skeletal remains. Specifically, non-invasive analysis of human remains is permissible provided that the analysis and collection of resulting data (1) are accomplished with respect for the dignity of the individual, (2) do not violate the last-known desire of the deceased, (3) do not adversely impact the right of the next of kin to perform a ceremonious and decent disposal of the remains, and (4) do not unduly or maliciously violate the privacy interests of the next of kin.

    18. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

      Science.gov (United States)

      Geula, Shay; Moshitch-Moshkovitz, Sharon; Dominissini, Dan; Mansour, Abed AlFatah; Kol, Nitzan; Salmon-Divon, Mali; Hershkovitz, Vera; Peer, Eyal; Mor, Nofar; Manor, Yair S; Ben-Haim, Moshe Shay; Eyal, Eran; Yunger, Sharon; Pinto, Yishay; Jaitin, Diego Adhemar; Viukov, Sergey; Rais, Yoach; Krupalnik, Vladislav; Chomsky, Elad; Zerbib, Mirie; Maza, Itay; Rechavi, Yoav; Massarwa, Rada; Hanna, Suhair; Amit, Ido; Levanon, Erez Y; Amariglio, Ninette; Stern-Ginossar, Noam; Novershtern, Noa; Rechavi, Gideon; Hanna, Jacob H

      2015-02-27

      Naïve and primed pluripotent states retain distinct molecular properties, yet limited knowledge exists on how their state transitions are regulated. Here, we identify Mettl3, an N(6)-methyladenosine (m(6)A) transferase, as a regulator for terminating murine naïve pluripotency. Mettl3 knockout preimplantation epiblasts and naïve embryonic stem cells are depleted for m(6)A in mRNAs, yet are viable. However, they fail to adequately terminate their naïve state and, subsequently, undergo aberrant and restricted lineage priming at the postimplantation stage, which leads to early embryonic lethality. m(6)A predominantly and directly reduces mRNA stability, including that of key naïve pluripotency-promoting transcripts. This study highlights a critical role for an mRNA epigenetic modification in vivo and identifies regulatory modules that functionally influence naïve and primed pluripotency in an opposing manner. Copyright © 2015, American Association for the Advancement of Science.

    19. Transgenerational soil-mediated differences between plants experienced or naïve to a grass invasion.

      Science.gov (United States)

      Deck, Anna; Muir, Adrianna; Strauss, Sharon

      2013-10-01

      Invasive species may undergo rapid change as they invade. Native species persisting in invaded areas may also experience rapid change over this short timescale relative to native populations in uninvaded areas. We investigated the response of the native Achillea millefolium to soil from Holcus lanatus-invaded and uninvaded areas, and we sought to determine whether differential responses between A. millefolium from invaded (invader experienced) and uninvaded (invader naïve) areas were mediated by soil community changes. Plants grown from seed from experienced and naïve areas responded differently to invaded and uninvaded soil with respect to germination time, biomass, and height. Overall, experienced plants grew faster and taller than their naïve counterparts. Naïve native plants showed negative feedbacks with their home soil and positive feedbacks with invaded soil; experienced plants were less responsive to soil differences. Our results suggest that native plants naïve to invasion may be more sensitive to soil communities than experienced plants, consistent with recent studies. While differences between naïve and experienced plants are transgenerational, our design cannot differentiate between differences that are genetically based, plastic, or both. Regardless, our results highlight the importance of seed source and population history in restoration, emphasizing the restoration potential of experienced seed sources.

    20. Peskütenin Kimyasal ve Mikrobiyolojik Özellikleri Üzerine bir Araştırma

      Directory of Open Access Journals (Sweden)

      Ahmet Kurt

      2015-02-01

      Full Text Available Bu araştırmada Sivas ili ve çevresinden şansa bağlı olarak alınan 14 adet Pesküten örneği üzerinde kimyasal ve mikrobiyolojik araştırmalar yapılmıştır. Belirlenen değerler ortalama olarak şöyledir: Kurumaddede %30.96, su %69.04, yağ %3.66, yağsız kurumadde %27.30, toplam kül %4.92, kurumaddede kül %15.95, kurumaddede tuz %12.18, saf kül %1.13, protein %22.08, şeker ve benzerleri %0.295 ve asitlik derecesi 83.90 SH olmuştur. Bunun yanında ortalama mikrobiyolojik içerik; toplam bakteri sayısı 3.735x106/g, koliform bakteri sayısı 5.69x104/g, maya ve küf sayısı 1.398x104/g, laktik bakteri sayısı 1.997x106/g, proteolitik bakteri sayısı, 12.34x104/g ve lipolitik bakteri sayısı 10.14x104/g olarak belirlenmiştir.

    1. A recombinant bivalent fusion protein rVE confers active and passive protection against Yersinia enterocolitica infection in mice.

      Science.gov (United States)

      Singh, Amit Kumar; Kingston, Joseph Jeyabalaji; Murali, Harishchandra Sripathy; Batra, Harsh Vardhan

      2014-03-05

      In the present study, a bivalent chimeric protein rVE comprising immunologically active domains of Yersinia pestis LcrV and YopE was assessed for its prophylactic abilities against Yersinia enterocolitica O:8 infection in murine model. Mice immunized with rVE elicited significantly higher antibody titers with substantial contribution from the rV component (3:1 ratio). Robust and significant resistance to Y. enterocolitica infection with 100% survival (Penterocolitica O:8 against the 75%, 60% and 75% survival seen in mice immunized with rV, rE, rV+rE, respectively. Macrophage monolayer supplemented with anti-rVE polysera illustrated efficient protection (89.41% survival) against challenge of Y. enterocolitica O:8. In contrast to sera from sham-immunized mice, immunization with anti-rVE polysera provided complete protection to BALB/c mice against I.P. challenge with 10(8)CFU of Y. enterocolitica O:8 and developed no conspicuous signs of infection in necropsy. The histopathological analysis of microtome sections confirmed significantly reduced lesion size or no lesion in liver and intestine upon infection in anti-rVE immunized mice. The findings from this study demonstrated the fusion protein rVE as a potential candidate subunit vaccine and showed the functional role of antibodies in protection against Y. enterocolitica infections. Copyright © 2014 Elsevier Ltd. All rights reserved.

    2. The management of forensic patients in Victoria: the more things change, the more they remain the same

      OpenAIRE

      Ruffles, Janet

      2017-01-01

      The introduction, in 1997, of the Crimes (Menta/Impairment and Unfitness to be Tried) Act 1997 (Vic) (CMIA) marked dramatic legal and procedural changes to the common law system governing the post-acquittal detention of persons found not guilty by reason of insanity in Victoria which had endured for almost 200 years. The CMIA's express aim to restore the balance between community safety and the rights of persons found not guilty by reason of mental impairment (NGRMI) (as the ve...

    3. Geleneksel ve Elektronik Eser Sahiplerinin Telif Hakları, Dijital Haklar Yönetimi: Uluslararası Düzenlemeler ve Fikir ve Sanat Eserleri Kanunu Çerçevesinde Bir Değerlendirme = Copyright of Traditional and Electronic Works’ Owners, Digital Rights Management: An Evaluation within the Framework of International Regulations and Law on Intellectual and Artistic Works

      OpenAIRE

      Metin Turan

      2016-01-01

      Bilgi ve iletişim teknolojilerinin gelişmesi ile fikri haklar alanında da değişiklikler kaçınılmaz olmuştur. Teknolojik imkânların gelişimi ve dijitalleşme ile dijital eserlerin üretimiyle birlikte telif haklarında sorunlar ortaya çıkmaktadır. Çalışmada, genel olarak, telif haklarının dijital eserlere ve dijital haklar yönetimine yönelik incelenmesi amaçlanmaktadır. Çalışmanın kapsamını dijital haklar yönetimi çerçevesinde 5846 sayılı Fikir ve Sanat Eserleri Kanunu oluşturmaktadır. Bu kapsamd...

    4. Quantitative measurements of autobiographical memory content.

      Directory of Open Access Journals (Sweden)

      Robert S Gardner

      Full Text Available Autobiographical memory (AM, subjective recollection of past experiences, is fundamental in everyday life. Nevertheless, characterization of the spontaneous occurrence of AM, as well as of the number and types of recollected details, remains limited. The CRAM (Cue-Recalled Autobiographical Memory test (http://cramtest.info adapts and combines the cue-word method with an assessment that collects counts of details recalled from different life periods. The SPAM (Spontaneous Probability of Autobiographical Memories protocol samples introspection during everyday activity, recording memory duration and frequency. These measures provide detailed, naturalistic accounts of AM content and frequency, quantifying essential dimensions of recollection. AM content (∼20 details/recollection decreased with the age of the episode, but less drastically than the probability of reporting remote compared to recent memories. AM retrieval was frequent (∼20/hour, each memory lasting ∼30 seconds. Testable hypotheses of the specific content retrieved in a fixed time from given life periods are presented.

    5. Content Maps: A Teaching and Assessment Tool for Content Knowledge

      Science.gov (United States)

      Ward, Phillip; Lehwald, Harry; Lee, Yun Soo

      2015-01-01

      Developing content knowledge in teachers presents a constant challenge for teacher educators. This article introduces a teaching and assessment tool called a "content map," which allows teacher educators, teachers, and coaches to conceptualize the scope, sequence, and relational characteristics of the content being taught. Content maps…

    6. Tekirdağ İlinde Yetiştirilen Bazı Sebze ve Meyvelerde Nitrat ve Nitrit Miktarları Üzerinde Araştırmalar

      Directory of Open Access Journals (Sweden)

      Harun Dıraman

      2015-02-01

      Full Text Available Meyve ve sebzelerin doğal yapılarında bulunan nitrat ve nitritin miktarları, günümüzde çevre kirlenmesinin gıdalar üzerindeki etkisini gösteren önemli parametrelerdendir. Nitrat ve nitritler gerekli ortamı buldukları zaman kanserojen bileşenlere dönüşmektedirler. Nitrat ve nitritin tayininde çeşitli kimyasal yöntemler kullanılmaktadır. Bu araştırmada ISO tarafından meyve ve sebzelerde nitrat ve nitrit belirlenmesinde referans metot olarak verilen moleküler absorpsiyon spektrofotometrik metot kullanılmıştır.Tekirdağ ilinin farklı yerleşim birimlerinden toplanan toplam 96 örnek üzerinde çalışılmıştır. Ispanak, marul, taze fasulye, patates, elma ve üzümde mg/kg taze ağırlık üzerinden belirlenen ortalama nitrat değerleri sırası ile 362.5, 685.6, 168.6, 777.9, 18.1, 16.6 olmuştur. Nitrit miktarları ise  çok düşük ve önemsiz düzeyde bulunmuştur. Örnekler üzerindeki nitrat ve nitrit miktarlarıyla ilgili istatistiki değerlendirmede  yapılan gruplar arasında önemli farklılık olduğu bulunmuştur. Örneklerin nitrat miktarlarının Türk Gıda Kodeksi tarafından izin verilen  maksimum değerlerin altında ve düşük  olduğu görülmüştür.

    7. Meyve Konservelerinde ve Sularında Bozulmalara Neden Olan Küf Mantarları

      Directory of Open Access Journals (Sweden)

      Jale Acar

      2015-02-01

      Full Text Available Bakteriler, meyve suları ve konservelerinin bozulmalarında pek önemli rol oynamadıkları halde mayalar ve özellikle küf mantarları bu bozulmalarda önemli bir yer alırlar. Çeşitli mikroorganizmaların gelişme isteklerinin farklı olması buna neden olmaktadır. Küf mantarlarının büyük bir kısmı ancak aerob koşullar altında gelişebilirler. Bu gelişme en fazla yüzeydedir. Konserve kutularının hermetikli olan kapatılması ve tepe boşluğunda çok az oksijen bulunması yüzeyde küf mantarlarının gelişmesini önlemekle beraber Byssochlamys cinsinden küf mantarları anaerob koşullar altında fazla olmasa bile gelişebilmektedirler. Küf mantarları bakterilere oranla az miktarda suya gereksinim duyarlar. Aspergillus glaucus ve birçok Penicillium türleri kserofil olup aktif suyun çok düşük olduğu 0.70-0.75 gelişebilmelerine karşın bu değer bakterilerde 0.90-0.98 arasındadır. Çok az miktardaki su örneğin, yüzeydeki kondense su pastörizasyonda öldürülemeyen veya sonradan herhangi bir şekilde reçel kabına giren küflerin gelişmesine yardımcı olabilir. Sonradan bulaşma özellikle evlerde yapılan ve soğuduktan sonra kapağı kapatılan, özellikle reçel kabı selofan kağıdı ile kapatılıyorsa, sık sık görülmektedir. Diğer taraftan kaplar reçel soğutulmadan kapatılacak olursa suyun kondense olma miktarı artmaktadır.

    8. Decontamination and management of human remains following incidents of hazardous chemical release.

      Science.gov (United States)

      Hauschild, Veronique D; Watson, Annetta; Bock, Robert

      2012-01-01

      To provide specific guidance and resources for systematic and orderly decontamination of human remains resulting from a chemical terrorist attack or accidental chemical release. A detailed review and health-based decision criteria protocol is summarized. Protocol basis and logic are derived from analyses of compound-specific toxicological data and chemical/physical characteristics. Guidance is suitable for civilian or military settings where human remains potentially contaminated with hazardous chemicals may be present, such as sites of transportation accidents, terrorist operations, or medical examiner processing points. Guidance is developed from data-characterizing controlled experiments with laboratory animals, fabrics, and materiel. Logic and specific procedures for decontamination and management of remains, protection of mortuary affairs personnel, and decision criteria to determine when remains are sufficiently decontaminated are presented. Established procedures as well as existing materiel and available equipment for decontamination and verification provide reasonable means to mitigate chemical hazards from chemically exposed remains. Unique scenarios such as those involving supralethal concentrations of certain liquid chemical warfare agents may prove difficult to decontaminate but can be resolved in a timely manner by application of the characterized systematic approaches. Decision criteria and protocols to "clear" decontaminated remains for transport and processing are also provided. Once appropriate decontamination and verification have been accomplished, normal procedures for management of remains and release can be followed.

    9. İş Motivasyonunun Çalışan Bağlılığı ve İşten Ayrılma Eğilimi Üzerindeki Etkileri = The Effects of Employee Work Motivation on Employee Commitment and Turnover Intention

      Directory of Open Access Journals (Sweden)

      Adnan CEYLAN

      2005-01-01

      Full Text Available In this study conducted on 84 public ve private sector employees, the relationships between organizational commitment, motivation to work ve turnover intention are investigated ve to determine the statistically significant relations, Allen ve Meyer's model is used. Statistically coherent corellations between affective, continuance, normative commitment ve motivation to work ve their impact on turnover intention is also investigated by regression analysis. This study serves as an important guide for those who are interested in understanding ve increasing employee commitment.

    10. Content Documents Management

      Science.gov (United States)

      Muniz, R.; Hochstadt, J.; Boelke J.; Dalton, A.

      2011-01-01

      The Content Documents are created and managed under the System Software group with. Launch Control System (LCS) project. The System Software product group is lead by NASA Engineering Control and Data Systems branch (NEC3) at Kennedy Space Center. The team is working on creating Operating System Images (OSI) for different platforms (i.e. AIX, Linux, Solaris and Windows). Before the OSI can be created, the team must create a Content Document which provides the information of a workstation or server, with the list of all the software that is to be installed on it and also the set where the hardware belongs. This can be for example in the LDS, the ADS or the FR-l. The objective of this project is to create a User Interface Web application that can manage the information of the Content Documents, with all the correct validations and filters for administrator purposes. For this project we used one of the most excellent tools in agile development applications called Ruby on Rails. This tool helps pragmatic programmers develop Web applications with Rails framework and Ruby programming language. It is very amazing to see how a student can learn about OOP features with the Ruby language, manage the user interface with HTML and CSS, create associations and queries with gems, manage databases and run a server with MYSQL, run shell commands with command prompt and create Web frameworks with Rails. All of this in a real world project and in just fifteen weeks!

    11. ULUSLARARASI TİCARET TEORİLERİ ve PAUL R.KRUGMAN’IN KATKILARI

      Directory of Open Access Journals (Sweden)

      Esra YÜKSEL

      2012-11-01

      Full Text Available INTERNATIONAL TRADE THEORIES AND THE CONTRIBUTIONS OF PAUL R. KRUGMANAbstract: International trade theories try to explain that free international trade provides increasing welfare for countries under given conditions. International trade theories are transformed and developed by differentiating conditions of natural and acquired endowments of countries by time.  Main aim of this study is to investigate contribution of Krugman by comparing literature on international trade theories. In addition to traditional international trade theories, Krugman states that international trade can occur and can be  profitable among countries whose technology, production cost and preferences are similar. Krugman emphasizes that monopolistic competition and product differentiation can contribute international trade. Free international trade expands markets for the firms and countries, in this way, expanding markets increases production scale of firms leading to decreasing costs. Main result of study is that Krugman contributes international trade theory by developing models indicating increasing gains for countries from international trade and by explaining differentiating dynamics of international trade.   Keywords: International Trade Theories, Paul Krugman,  Gains From International Trade. ULUSLARARASI TİCARET TEORİLERİ vePAUL R.KRUGMAN’IN  KATKILARIÖzet: Uluslararası ticaret teorileri, uluslararası serbest ticaretin, belirli koşullar altında, ülkeler için önemli refah artışları sağlayacağını ortaya koymaya çalışmaktadır.    Geliştirilen teoriler,  ülkelerin doğal ve kazanılmış üstünlüklerindeki dinamizmine bağlı olarak değişim göstermekte ve gelişmektedir. Bu çalışmanın temel amacı, Krugman’nın uluslararası ticaret teorilerine yaptığı katkıyı, uluslararası ticaret literatürünü karşılaştırmalı olarak inceleyerek ortaya koymaktır. Krugman’ın görüşleri, geleneksel uluslararas

    12. Çanakkale Muharebelerinde Gelibolu ve Civarı

      Directory of Open Access Journals (Sweden)

      Ahmet ESENKAYA

      2010-01-01

      existing in Gallipoli and consisting of Army Chief of Medical Staff Sergeant and Army Headquarters Medical Staff and the ones needed treatment urgently as not be able to transfer back were taken from the ship and their referrals were made to the two hospitals in Gallipoli. The bed capacity of the Military Hospital of Gallipoli had been increased from 250 to 1000 before and also a Red Crescent hospital with a 200-bed capacity in the French school and a 150-bed war hospital were opened. These hospitals were moved to Lapseki partially and mostly to Tekirdag upon the bombarding of the Gallipoli centre. The remaining part having 150 beds was in the situation on the 4th of May and left for the emergency cases. The Medical School students, who were employed in the hospitals of Istanbul province for the maintenance of the wounded increasing in number, were brought to Canakkale with the Sungurlu Battalion boarded the Ship of Resit Pasha in April, 1915 and then to Gallipoli under the auspices of the Ottoman destroyer and finally they were distributed to the hospitals.

    13. Taxa de mortalidade por acidentes de trâsito e frota de veículos

      Directory of Open Access Journals (Sweden)

      Samuel Kilsztajn

      2001-06-01

      Full Text Available OBJETIVO: A taxa de mortalidade específica por acidentes de trânsito de veículos a motor é usualmente utilizada para efeito das políticas de saúde pública. Para mensurar o grau de violência no trânsito, foi realizado estudo com o objetivo de analisar o número de óbitos por acidentes de trânsito por veículo a motor. MÉTODOS: Com base nos dados sobre frota de veículos, população e óbitos por acidente de trânsito, publicados no Statiscal Yearbook (1999, Demografic Yearbook (1997, Denatran (1999, Ministério da Saúde (2000 e Fundação IBGE (2000, foram estudados 61 países e 51 localidades brasileiras.A taxa de mortalidade específica foi decomposta em número de veículos por habitante e número de óbitos por veículo. Numa primeira aproximação, cada uma das amostras (internacional e brasileira foi subdividida em três grupos, de acordo com o número de veículos por habitante, para estudo da relação entre os três índices. Para testar a significância dessa relação, foi estimada uma função de regressão log-linear. RESULTADOS: Os resultados para as estimativas internacionais, assim como as do Brasil, demonstraram que, quanto maior o número de veículos por habitante, menor o número de óbitos por acidentes de trânsito por veículo, tendo-se elasticidade da ordem de -1,067, para as estimativas internacionais, e de -0,515, para as do Brasil. CONCLUSÕES: Para uma política de prevenção dos acidentes de trânsito, os resultados encontrados indicam a necessidade de estudar os fatores que possam explicar o maior número de óbitos por veículo nas regiões com menor número de veículos por habitante.

    14. VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs.

      Science.gov (United States)

      Sidibé, Adama; Polena, Helena; Pernet-Gallay, Karin; Razanajatovo, Jeremy; Mannic, Tiphaine; Chaumontel, Nicolas; Bama, Soumalamaya; Maréchal, Irène; Huber, Philippe; Gulino-Debrac, Danielle; Bouillet, Laurence; Vilgrain, Isabelle

      2014-08-01

      Covalent modifications such as tyrosine phosphorylation are associated with the breakdown of endothelial cell junctions and increased vascular permeability. We previously showed that vascular endothelial (VE)-cadherin was tyrosine phosphorylated in vivo in the mouse reproductive tract and that Y685 was a target site for Src in response to vascular endothelial growth factor in vitro. In the present study, we aimed to understand the implication of VE-cadherin phosphorylation at site Y685 in cyclic angiogenic organs. To achieve this aim, we generated a knock-in mouse carrying a tyrosine-to-phenylalanine point mutation of VE-cadherin Y685 (VE-Y685F). Although homozygous VE-Y685F mice were viable and fertile, the nulliparous knock-in female mice exhibited enlarged uteri with edema. This phenotype was observed in 30% of females between 4 to 14 mo old. Histological examination of longitudinal sections of the VE-Y685F uterus showed an extensive disorganization of myometrium and endometrium with highly edematous uterine glands, numerous areas with sparse cells, and increased accumulation of collagen fibers around blood vessels, indicating a fibrotic state. Analysis of cross section of ovaries showed the appearance of spontaneous cysts, which suggested increased vascular hyperpermeability. Electron microscopy analysis of capillaries in the ovary showed a slight but significant increase in the gap size between two adjacent endothelial cell membranes in the junctions of VE-Y685F mice (wild-type, 11.5 ± 0.3, n = 78; and VE-Y685F, 12.48 ± 0.3, n = 65; P = 0.045), as well as collagen fiber accumulation around capillaries. Miles assay revealed that either basal or vascular endothelial growth factor-stimulated permeability in the skin was increased in VE-Y685F mice. Since edema and fibrotic appearance have been identified as hallmarks of initial increased vascular permeability, we conclude that the site Y685 in VE-cadherin is involved in the physiological regulation of capillary

    15. Predictors of patients remaining anovulatory during clomiphene citrate induction of ovulation in normogonadotropic oligoamenorrheic infertility

      NARCIS (Netherlands)

      B. Imani (Babak); M.J.C. Eijkemans (René); E.R. te Velde (Egbert); J.D.F. Habbema (Dik); B.C.J.M. Fauser (Bart)

      1998-01-01

      textabstractThe diagnostic criteria used to identify patients suffering from polycystic ovary syndrome remain controversial. The present prospective longitudinal follow-up study was designed to identify whether certain criteria assessed during standardized initial

    16. BTC method for evaluation of remaining strength and service life of bridge cables.

      Science.gov (United States)

      2011-09-01

      "This report presents the BTC method; a comprehensive state-of-the-art methodology for evaluation of remaining : strength and residual life of bridge cables. The BTC method is a probability-based, proprietary, patented, and peerreviewed : methodology...

    17. Cognitive bias in forensic anthropology: visual assessment of skeletal remains is susceptible to confirmation bias.

      Science.gov (United States)

      Nakhaeizadeh, Sherry; Dror, Itiel E; Morgan, Ruth M

      2014-05-01

      An experimental study was designed to examine cognitive biases within forensic anthropological non-metric methods in assessing sex, ancestry and age at death. To investigate examiner interpretation, forty-one non-novice participants were semi randomly divided into three groups. Prior to conducting the assessment of the skeletal remains, two of the groups were given different extraneous contextual information regarding the sex, ancestry and age at death of the individual. The third group acted as a control group with no extraneous contextual information. The experiment was designed to investigate if the interpretation and conclusions of the skeletal remains would differ amongst participants within the three groups, and to assess whether the examiners would confirm or disagree with the given extraneous context when establishing a biological profile. The results revealed a significant biasing effect within the three groups, demonstrating a strong confirmation bias in the assessment of sex, ancestry and age at death. In assessment of sex, 31% of the participants in the control group concluded that the skeleton remains were male. In contrast, in the group that received contextual information that the remains were male, 72% concluded that the remains were male, and in the participant group where the context was that the remains were of a female, 0% of the participants concluded that the remains were male. Comparable results showing bias were found in assessing ancestry and age at death. These data demonstrate that cognitive bias can impact forensic anthropological non-metric methods on skeletal remains and affects the interpretation and conclusions of the forensic scientists. This empirical study is a step in establishing an evidence base approach for dealing with cognitive issues in forensic anthropological assessments, so as to enhance this valuable forensic science discipline. Copyright © 2013 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights

    18. An analysis of the alleged skeletal remains of Carin Göring.

      Directory of Open Access Journals (Sweden)

      Anna Kjellström

      Full Text Available In 1991, treasure hunters found skeletal remains in an area close to the destroyed country residence of former Nazi leader Hermann Göring in northeastern Berlin. The remains, which were believed to belong to Carin Göring, who was buried at the site, were examined to determine whether it was possible to make a positive identification. The anthropological analysis showed that the remains come from an adult woman. The DNA analysis of several bone elements showed female sex, and a reference sample from Carin's son revealed mtDNA sequences identical to the remains. The profile has one nucleotide difference from the Cambridge reference sequence (rCRS, the common variant 263G. A database search resulted in a frequency of this mtDNA sequence of about 10% out of more than 7,000 European haplotypes. The mtDNA sequence found in the ulna, the cranium and the reference sample is, thus, very common among Europeans. Therefore, nuclear DNA analysis was attempted. The remains as well as a sample from Carin's son were successfully analysed for the three nuclear markers TH01, D7S820 and D8S1179. The nuclear DNA analysis of the two samples revealed one shared allele for each of the three markers, supporting a mother and son relationship. This genetic information together with anthropological and historical files provides an additional piece of circumstantial evidence in our efforts to identify the remains of Carin Göring.

    19. Spontaneous recovery of locomotion induced by remaining fibers after spinal cord transection in adult rats.

      Science.gov (United States)

      You, Si-Wei; Chen, Bing-Yao; Liu, Hui-Ling; Lang, Bing; Xia, Jie-Lai; Jiao, Xi-Ying; Ju, Gong

      2003-01-01

      A major issue in analysis of experimental results after spinal cord injury is spontaneous functional recovery induced by remaining nerve fibers. The authors investigated the relationship between the degree of locomotor recovery and the percentage and location of the fibers that spared spinal cord transection. The spinal cords of 12 adult rats were transected at T9 with a razor blade, which often resulted in sparing of nerve fibers in the ventral spinal cord. The incompletely-transected animals were used to study the degree of spontaneous recovery of hindlimb locomotion, evaluated with the BBB rating scale, in correlation to the extent and location of the remaining fibers. Incomplete transection was found in the ventral spinal cord in 42% of the animals. The degree of locomotor recovery was highly correlated with the percentage of the remaining fibers in the ventral and ventrolateral funiculi. In one of the rats, 4.82% of remaining fibers in unilateral ventrolateral funiculus were able to sustain a certain recovery of locomotion. Less than 5% of remaining ventrolateral white matter is sufficient for an unequivocal motor recovery after incomplete spinal cord injury. Therefore, for studies with spinal cord transection, the completeness of sectioning should be carefully checked before any conclusion can be reached. The fact that the degree of locomotor recovery is correlated with the percentage of remaining fibers in the ventrolateral spinal cord, exclusive of most of the descending motor tracts, may imply an essential role of propriospinal connections in the initiation of spontaneous locomotor recovery.

    20. Content Analysis of Tobacco-related Twitter Posts

      Science.gov (United States)

      Myslín, Mark; Zhu, Shu-Hong; Conway, Michael

      2013-01-01

      Objective We present results of a content analysis of tobacco-related Twitter posts (tweets), focusing on tweets referencing e-cigarettes and hookah. Introduction Vast amounts of free, real-time, localizable Twitter data offer new possibilities for public health workers to identify trends and attitudes that more traditional surveillance methods may not capture, particularly in emerging areas of public health concern where reliable statistical evidence is not readily accessible. Existing applications include tracking public informedness during disease outbreaks [1]. Twitter-based surveillance is particularly suited to new challenges in tobacco control. Hookah and e-cigarettes have surged in popularity, yet regulation and public information remain sparse, despite controversial health effects [2,3]. Ubiquitous online marketing of these products and their popularity among new and younger users make Twitter a key resource for tobacco surveillance. Methods We collected 7,300 tobacco-related Twitter posts at 15-day intervals from December 2011 to July 2012, using ten general keywords such as cig* and hookah. Each tweet was manually classified using a tri-axial scheme, capturing genre (firsthand experience, joke, news, …), theme (underage usage, health, social image, …), and sentiment (positive, negative, neutral). Machine-learning classifiers were trained to detect tobacco-related vs. irrelevant tweets as well as each of the above categories, using Naïve Bayes, k-Nearest Neighbors, and Support Vector Machine algorithms. Finally, phi correlation coefficients were computed between each of the categories to discover emergent patterns. Results The most prevalent genre of tweets was personal experience, followed by categories such as opinion, marketing, and news. The most common themes were hookah, cessation, and social image, and sentiment toward tobacco was more positive (26%) than negative (20%). The most highly correlated categories were social image