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  1. Accident vasculaire cerebral ischemique post-chimiotherapie pour ...

    African Journals Online (AJOL)

    Patiente âgée de 46ans, traitée pour une épilepsie généralisée, et sans facteur de risque cardiovasculaire, est suivie pour un cancer du sein. Elle a présenté au décours de la chimiothérapie un accident vasculaire cérébral ischémique sylvien droit confirmé au scanner cérébral. Les explorations cardiaques sont normales, ...

  2. Léiomyome vasculaire de l'avant bras: présentation d'un cas clinique et revue de la literature

    Science.gov (United States)

    Moncef, Erraji; Abdessamad, Kharraji; Najib, Abassi; Najib, Abdeljawad; Yacoubi, Hicham

    2014-01-01

    Le léiomyome est une tumeur bénigne vasculaire qui peut se présenter sous la forme d'une masse localisée; cependant le diagnostic ne peut en être clinique. Le diagnostic définitif repose sur la réalisation de multiples examens d'imagerie radiologique et sur le résultat de l'examen histologique.une fois traitée par une excision large, passant en zone saine sur le vaisseau, la tumeur à un faible taux de récidive. Nous en rapportant un cas de patiente ayant un léiomyome siégeant au niveau de l'avant bras. PMID:25838850

  3. Qualite de vie apres un accident vasculaire cerebral au Senegal: a ...

    African Journals Online (AJOL)

    Abstract. Introduction: L'accident vasculaire cérébral (AVC) constitue une cause majeure de mortalité et de handicap chez les survivants. La qualité de vie dépend de la nature du handicap et de sa perception par le patient, son entourage et la communauté. Objectif: Notre objectif était d'évaluer le handicap après un AVC et ...

  4. Prediction of vascular cerebral accidents by PET T.D.M. with {sup 18}F-F.D.G; Prediction des accidents vasculaires cerebraux par la TEP -TDM vasculaire au 18F-FDG

    Energy Technology Data Exchange (ETDEWEB)

    Grandpierre, S.; Chevalier, O.; Thomas, V.; Netter, F.; Meneroux, B.; Karcher, G.; Marie, P.Y. [Service de medecine nucleaire, CHU de Nancy, (France); Desandes, E. [departement d' informatique medical, centre Alexis-Vautrin, Nancy, (France)

    2009-05-15

    This study is the first to show a relationship between the vascular captation of the F.D.G. in PET and the risk of a later ischemic cerebral vascular accident. this relation seems particularly strong for the sources of the carotids junction, so that the PET with F.D.G. could be useful to evaluate the stability of atheromas injuries in this area. (N.C.)

  5. Anomalies hematologiques au cours des accidents vasculaires ...

    African Journals Online (AJOL)

    Anomalies hematologiques au cours des accidents vasculaires cerebraux a Abidjan des (Cote d'Ivoire) ... Introduction: En Côte d'Ivoire, les accidents vasculaires cérébraux (AVC) sont de plus en ... The objective of the study was to report the hematological abnormalities in the stroke among black African patients in Abidjan.

  6. Avant-Garde vs. 'Avant-Garde'

    DEFF Research Database (Denmark)

    Hansen, Kamma Overgaard

    2017-01-01

    to address earlier Avant-Garde phenomena, eg. the painting style and mask motives of the CoBrA movement, and figures obviously referring to Dada, Surrealism and the works of Joseph Beuys. Also, the 1980s artists facilitated numerous other activities familiar to the 1960s art scene. Consequently...

  7. Accidents Vasculaires Cerebraux (AVC) au Centre Hospitalier ...

    African Journals Online (AJOL)

    Mots clés: accident vasculaire cérébral, AVC ischémique, AVC hémorragique, CHU Kara, Togo, zone semi-rurale. English Title: Stroke in the Kara Teaching Hospital in a semi rural area in Togo: epidemiological and outcome aspects. English Abstract. Purpose: To describe the epidemiology and outcome of stroke in Kara ...

  8. Demence vasculaire en milieu hospitalier au Togo | Kombate ...

    African Journals Online (AJOL)

    La démence vasculaire représente la deuxième cause de démence après la maladie d'Alzheimer. Objectif: Evaluer les aspects cliniques et paracliniques des démences vasculaires dans le service de neurologie du CHU-Campus de Lomé. Méthode: Un score de MMS <24 associés à des lésions vasculaires cérébrales à la ...

  9. Malformations vasculaires au cours du syndrome de Williams-Beuren

    African Journals Online (AJOL)

    Malformations vasculaires au cours du syndrome de Williams-Beuren: à propos de trois nouvelles observations. Hicham Sator, Fatima Ezzahra Rhouni, Ibitihale Benjouad, Fatima Ezzahra Rhouni, Ibitihale Benjouad, Rachida Dafiri, Latifa Chat ...

  10. Laid Back Avant-Garde

    DEFF Research Database (Denmark)

    Degn Johansson, Troels

    2010-01-01

    to develop our understanding of--von Trier; apparently not of Laid Back. The paper thus seeks to approach von Trier as a conceptual artist with a special interest in the notion of developing society (the avant-garde position) and being a popular figure (“folkelig”, appreciated by the people) at the same time......; an interest which historically both evokes ideas of pop music and pop culture, the role of the artist in a national, social-democratic context, and the role of the avant-garde artist after the completion of such projects as situationism and the American neo-avant-garde. In this manner, the paper finally seeks...... controversial. Whereas Laid Back has been one of the largest commercial successes of the Danish music industry due to the success of a handful of pop hits (in Germany, mainly), the duo has never been recognized for its artistic contribution. A few years after his public statement, von Trier directed...

  11. The Second Avant-Garde

    DEFF Research Database (Denmark)

    Karpova, Yulia

    2018-01-01

    envisioned a new role of things as agents of progressive social relations, as “comrades” rather than mere possessions. My book will identify the second historical attempt at creating a powerful alternative to capitalist commodities in the Cold War era. It will be, however, not a history of Soviet industrial......My book will explore the specific legacy of the avant-garde in design and decorative art of post-war Soviet Russia. It will be centered on the notion of socialist objects that was pivotal in the particular stream of the 1920s Russian avant-garde, known as productivism. The theorists of productivism...... design – a specific profession institutionalized in the USSR in 1962 – but, instead, a shared history of objects, hand-made as well as machine made, mass-produced as well as unique, utilitarian as well as challenging the conventional notion of utility. By exploring this shared history, I pursue a twofold...

  12. Depression chez l'hemiplegique vasculaire a Brazzaville | Ossou ...

    African Journals Online (AJOL)

    Cette étude avait pour objectif d'améliorer la prise en charge globale des patients atteints d'accident vasculaire cérébral (AVC) en décrivant les aspects ... La dépression a été évaluée par le questionnaire de Beck ; l'autonomie fonctionnelle et la qualité de vie, respectivement par l'index de Barthel et le Stroke Impact Scale.

  13. The avant-garde and Aesthetic Values

    Directory of Open Access Journals (Sweden)

    T. Pawlowski

    1985-05-01

    Full Text Available Does it make sense to speak of aesthetic values in avant-garde art? Is not the very formulation of the them e tainted with contradiction? After all, avant-garde artists have postulated repeatedly, and quite unambiguously, that it is not their aim to create aesthetic values; we do not want to have anything to do with aesthetic values — they used to add contemptuously. The presence of aesthetic values in art depends on its definite features. Until recently many of them were unanimously looked upon as the constitutive properties of art. Yet, it was exactly the avant-garde that called in question nearly all properties regarded earlier as the specific features of art. Perhaps, then, the problem posed in the title falls not only because of the postulated neutral, or even anti-aesthetic, attitude of the avant-garde, but also because the avant-garde is not art at all?

  14. Avant-Garde, Aestheticization and the Economy

    Directory of Open Access Journals (Sweden)

    Michael Müller

    2014-08-01

    Full Text Available It would very much seem as though the avant-garde in post-war Germany had initially lost sight of the previously politically grounded programmatic narratives. Moreover, it seemed quite obsolete to insist on the destruction of the affirmative. After all, had it not been the Nazis who had pursued such destruction far more successfully than the avant-gardes before them, albeit with completely opposite goals in mind?For this reason, it seemed so compelling to regard the restoration of the avant-garde via the renewed recourse to the autonomy of art as an expression of an anti-fascist stance. The linkage of emancipation of individual subjectivity and radical social change called for by the avant-gardes now collapses once again. In the years that followed, the conservative cultural position repeatedly turned on attempts to closely link aesthetic innovation with social change.This taming of a recalcitrant art was followed in the early 1970s, after a brief intermezzo at the end of the 1960s, by talk of the failure of the avant-garde, before being subjected to outrageous defamation ten years later (particularly in architecture.The question of whether today the universalization of the aesthetic has indirectly realized the hopes of the avant-gardes of an aesthetics of and in lived practice, will be the subject of my remarks.

  15. Un accident vasculaire hémorragique révélant une méningite à ...

    African Journals Online (AJOL)

    Un accident vasculaire hémorragique révélant une méningite à Neisseria meningitidis. M Savadogo, GRC Millogo, S Zabsonré. Abstract. L'accident vasculaire hémorragique et la méningite purulente constituent des urgences médicales chez la personne âgée. L'objectif est de rapporter un cas d'accident vasculaire ...

  16. Theater: En Garde, Avant-Garde

    National Research Council Canada - National Science Library

    Sellar, Tom

    2010-01-01

    The author offers a survey of New York City's progressive theater scene. He considers how it has evolved over the first decade of the 21st century, which companies are doing the most inventive work, and what constitutes avant-garde...

  17. Rotavirus vaccine AVANT/GlaxoSmithKline.

    Science.gov (United States)

    Jones, T

    2001-07-01

    AVANT Immunotherapeutics (formerly Virus Research Institute) and GlaxoSmithKline are developing a live oral rotavirus vaccine with potential to elicit a broadly-protective immune response against the most prevalent strains of rotavirus. Following successful completion of a phase II clinical efficacy trial in June 1999, SmithKline Beecham (now GlaxoSmithKline) assumed responsibility for all subsequent clinical and other development activities [328635], [333677]. Following a licensing agreement, the vaccine was refined and renamed RIX-4414 [371713]. In May 2000, AVANT reported the results of a second-year surveillance extension of the phase II study. The results suggested that AVANT's two-dose oral rotavirus vaccine should be helpful in preventing rotavirus gastroenteritis (RGE) disease in young children for at least two years following administration [365202]. In March 2000, SmithKline Beecham reported that it had initiated phase I/II bridging studies in Europe and the company planned to start phase III safety and efficacy studies in 2001 after review with the health authorities [358963]. In October 2000, Dain Rauscher Wessels stated that an estimated market penetration of 30 to 40% suggested potential sales in excess of US $500 million pa. As a result, the analysts also estimated that incremental revenues to AVANT could be over US $50 million pa [411122].

  18. Scouting the Desert of the Real: Avant-Gardism of the Avant-Pop

    Directory of Open Access Journals (Sweden)

    Mojca Krevel

    2010-05-01

    Full Text Available The paper examines the legacy of the European historical Avant-Gardes from the perspective of the shift of paradigms immanent in the formation of the Postmodern epoch. The existing theories generally regard the Avant-Gardes as an unsuccessful attempt to redefine the function of art in the social, cultural and economic environment of the early 20th century. Examining the productivity and relevance of the historical Avant-Gardes from the perspective of the Avant-Pop, the first thoroughly Postmodern literary movement, I intend to show how the strategies of fragmentation and the breaking of organicity not only quintessentially defined the manner in which Modernity and its art came to an end, but how they also provided the basis forthe formation of culture and art that no longer functions according to Cartesian principles.

  19. Effet de la jachére sur l'expérimentation de la fusariose vasculaire ...

    African Journals Online (AJOL)

    Effet de la jachére sur l'expérimentation de la fusariose vasculaire du palmier à huile ( Elaeis guineensis Jacq ) : Effects of the fallow in the expression of oil-palm ( Elaeis guineensis Jacq ) vascular wilt.

  20. Historical Avant-gardes and Moving Images

    Directory of Open Access Journals (Sweden)

    Alfonso Puyal Sanz

    2017-05-01

    Full Text Available The special issue of index.comunicación, dedicated to ‘Cinema and artistic avant-gardes’, is the result of a harvest of works that have been selected in double blind peer review and which have been coordinated by Rafael Gómez Alonso, a professor at the Rey Juan University Carlos, and Alfonso Puyal, professor at the Universidad Complutense de Madrid. As a first idea, it should be emphasized that it is comforting for this magazine to host a number on cinematographic aesthetics, when the general tendency of academic communication publications is to gradually move away from the humanities to approach the social sciences.

  1. Diversité floristique des épiphytes et hémiparasites vasculaires de l ...

    African Journals Online (AJOL)

    Elle se base sur la complémentarité de la revue de la littérature et l'inventaire botanique. Pour chaque taxon, il est noté l'exposition au soleil, sa position sur le phorophyte, la phénophase et le phorophyte. L'étude des épiphytes et parasites vasculaires de la partie aérienne des plantes supérieures se fonde sur 28 espèces ...

  2. Purpura vasculaire révélant une granulomatose avec polyangéite: à ...

    African Journals Online (AJOL)

    Purpura vasculaire révélant une granulomatose avec polyangéite: à propos d'un cas. Olfa Berriche, Sonia Hammami. Abstract. La granulomatose avec polyangéite (GPA) est une vascularite systémique rare, caractérisée par une atteinte des voies aériennes supérieures, des poumons et des reins; cependant de nombreux ...

  3. Epuisement du capital vasculaire en hémodialyse: quelle issue?

    Science.gov (United States)

    Hajji, Meriam; Harzallah, Amel; Kaaroud, Hayet; Jerbi, Mona; Chargui, Soumaya; Younsi, Fethi El; Hamida, Fethi Ben; abdallah, Taieb Ben

    2016-01-01

    Malgré les progrès réalisés dans le traitement de l’insuffisance rénale chronique, l’accès vasculaire reste le maillon faible dans la thérapie de suppléance extrarénale et la principale source de morbidité chez les patients hémodialysés. Nous rapportons l’observation d’une jeune patiente ayant une insuffisance rénale chronique secondaire à une néphropathie vasculaire en hémodialyse périodique, confrontée précocement à un épuisement de son capital vasculaire, en raison de thromboses itératives des fistules artério-veineuses et l’échec de la dialyse péritonéale. Un déficit en protéine C a été objectivé. Elle a bénéficié de la mise en place d’un cathéter tunnelisé au niveau de l’oreillette droite par thoracotomie antéro-latérale droite à travers la veine cave inférieure non fonctionnel au bout de trois mois de son utilisation. Elle est depuis dialysée par ponction des veines jugulaires externes. PMID:28293353

  4. Epaisseur de l'intima-média carotidienne et facteurs de risque cardio-vasculaires

    Science.gov (United States)

    Herinirina, Nicolas Fanantenana; Rajaonarison, Lova Hasina Ny Ony Narindra; Herijoelison, Andry Roussel; Ahmad, Ahmad

    2015-01-01

    Introduction L’épaisseur intima-média de la carotide commune mesurée à l’échographie est un marqueur de risque cardio-vasculaire. L'objectif de ce travail est d’établir la corrélation entre l’épaisseur de l'intima-média carotidienne commune et les facteurs de risque cardio-vasculaire chez des sujets asymptomatiques. Méthodes Etude transversale descriptive et analytique portant sur 77 sujets de 40 ans et plus chez qui nous avons évalué les facteurs de risque cardio-vasculaire et analysé leur association avec l’épaisseur intima-média carotidienne commune. Résultats L’épaisseur intima-média augmentait avec l’âge. Les hommes avaient une épaisseur intima-média plus marquée que les femmes. L'hypertension artérielle, le diabète et la dyslipidémie sont corrélés à l’épaisseur de l'intima-média contrairement au tabagisme. Conclusion L’âge élevé et le sexe masculin sont les facteurs déterminants de la majoration de l’épaisseur intima-média carotidienne commune surtout si s'ajoutent l'hypertension artérielle, le diabète ou la dyslipidémie. PMID:26327990

  5. Revetements bioactifs a base de chondroitine sulfate et de facteurs de croissance pour applications vasculaires

    Science.gov (United States)

    Lequoy, Pauline

    Malgre des avancees technologiques indeniables, l'efficacite des implants biomedicaux est encore limitee par les biomateriaux synthetiques qui les composent, notamment en raison de leur incapacite a generer une reponse biologique adequate. En particulier, la guerison tissulaire autour des implants vasculaires reste problematique. Une etude de la litterature a montre que dans le cas des endoprotheses couvertes (tuyaux polymeriques utilises pour la reparation endovasculaire des anevrismes de l'aorte abdominale), le manque de guerison observe s'explique non seulement par l'inertie des biomateriaux utilises mais aussi par le fait que l'implant est insere dans un vaisseau malade favorisant la mort des cellules par apoptose et presentant une depletion cellulaire marquee. L'hypothese a la base de ce projet est qu'un revetement bioactif pourrait ameliorer la guerison et la colonisation de l'implant par les cellules vasculaires et ainsi favoriser l'attachement de l'implant dans le vaisseau malade afin de prevenir les complications a long terme. Dans ce contexte, deux molecules anti-apoptotiques ont ete selectionnees pour developper le revetement, la chondroitine sulfate (CS), un glycosaminoglycane de la matrice extracellulaire, et le facteur de croissance de l'epiderme (EGF) qui possede egalement un role important dans la guerison tissulaire. L'un des defis de ce projet est de preserver la bioactivite de ces molecules lors de leur immobilisation dans un revetement. Pour etablir une preuve de concept, nous avons demontre qu'un revetement CS+EGF obtenu par greffage covalent permet d'ameliorer significativement la survie des cellules vasculaires humaines (cellules musculaires lisses, CMLV, et fibroblastes) sur les materiaux realistes (PET, ePTFE). Apres avoir transfere ce revetement sur des implants commerciaux en ePTFE, des tests in vivo ont demontre une amelioration de la guerison grâce au revetement bioactif, cependant la guerison n'a pas ete totale dans la cavite

  6. 9/11 as Avant-Garde Art?

    Directory of Open Access Journals (Sweden)

    Richard Schechner

    2011-11-01

    Full Text Available Can the attacks of 9/11 be considered an avant-garde artistic event? This article aims to discuss, from the point of view of the intentionality of the act and of its reception, the performative character of that historical fact. To carry forward this intent, it presents a historical overview of avant-garde art, and discusses some of the historical and cultural conditions that supposedly operated as triggers of such an event. The text also focuses on the spectacular character of the event and the conditions for its appreciation in a society greatly delimited by the media.

  7. John Zorn: Autonomy and the Avant-Garde (excerpt

    Directory of Open Access Journals (Sweden)

    Ted Gordon

    2012-06-01

    Full Text Available This essay is an excerpt for a larger paper exploring the concept of autonomy as it emerges in the life and work of the composer, performer, record label executive and club-owner John Zorn. Zorn’s activities over his wide-ranging career span from performing at jazz lofts in the 1970s to winning the MacArthur “genius” grant in 2008, while maintaining his status as a prolific composer and producer of avant-garde music. In interviews, documentaries, and in his music, Zorn often comments on his status as an avant-garde producer, specifically within the context of the record industry and within New York City’s so-called “Downtown” scene. Economics take the forefront in determining artistic attitudes towards both production of music and the music itself, as Zorn has, seemingly, been forced by the “mainstream market” to create a parallel, vertically-integrated economic system to support the livelihood of himself and his collaborators. This excerpt, from the first third of the essay, unpacks Zorn’s relationship with Downtown scene, his conception of the avant-garde, and his attitude towards artists who have set precedents for Zorn’s version of autonomous cultural production. It also notes the idiosyncratic way that both Zorn and his critics have placed Zorn’s music both within and without two distinct traditions: Avant-Garde composition and free Jazz.

  8. Cosmologie L'Univers avant le Big Bang

    CERN Multimedia

    Rouat, Sylvie

    2003-01-01

    Tout n'a pas commencé par une explosion. L'histoire du cosmos avait débuté bien avant le Big Bang, si l'on suit la théorie défendue par les partisans d'une nouvelle cosmologie issue de la mystérieuse théorie des cordes

  9. A Cultural History of the Avant-Garde in the Nordic Countries 1900-1925

    DEFF Research Database (Denmark)

    The first publication to deal with the avant-garde in the Nordic countries at the start of the twentieth century. It is the first major historical work to consider the Nordic avant-garde in a transnational perspective which includes all the arts and to discuss the role of the avant-garde not only...

  10. THE IDENTITY OF THE ROMANIAN PRE-AVANT-GARDE

    Directory of Open Access Journals (Sweden)

    Dr. Paul DUGNEANU

    2011-05-01

    Full Text Available In the evolution and dialectics of the literary phenomenon at the end of the XIX century and the beginning of the XX century we can note a period of artistic fizzle, of confirming literary currents and movements, that vehemently deny the tradition and which, through some important elements, shall announce the historical avant-garde. We are referring to a series of artistic and literary currents, with a set of similar features, having a fetish for the shocking novelty and bracketing of the established and generally accepted values, without having the force of penetration, aggressiveness, coherence and spreading of the actual avant-garde: the fauvism, cubism, futurism, imagism, vorticism and others.

  11. Avant-garde: Making war, revolutionary politics and art

    Directory of Open Access Journals (Sweden)

    Jeremić-Molnar Dragana

    2008-01-01

    Full Text Available In the article the authors are dealing with the militant potential of the concept of avant-garde. Emerging in the politics and art in the first half of the 19th century and designed to ruin almost the whole tradition of 'bourgeois' enlightenment, political and artistic avant-garde was never capable of emancipating itself from its roots in strategic military thinking. Its true essence was to create battlefields in every domain of public life where the chance was given to ruin civil society - its politics, its art, its way of thinking, its civilization. In the name of freedom never heard of before, it spread violence and spread totalitarian seeds on the scorched soil. And in the end it was not defeated by its numerous enemies because it became victim of its own destructiveness.

  12. AvantGuard: An Instrument to Explore Autonomy

    Science.gov (United States)

    2007-11-01

    intersection to intersection.   AvantGuard supplies automatic convoy mission routing, based on the  Dijkstra   algorithm . It uses a threat  map: a... navigation  and basic flight planning. The Operator becomes less a pilot and more a director.  UAV Bonus Almost every field enjoys the same...situation awareness. Sometimes it is a full screen map. The transition  between the two is managed by the AvantGuard “Flywheel”  navigation . (See

  13. Avant-garde: The Convulsions of a Concept

    Directory of Open Access Journals (Sweden)

    Michael T. Jones

    1980-09-01

    Full Text Available The current status of the «avant-garde» provokes many questions, which include both inner-artistic matters and matters of history and society commonly associated with Marxist or reception-oriented thinkers. The convolution of questions cannot be disentangled; efforts to confront the dilemmas of the avant-garde cannot abstract from matters of commodification, recent reception, or the complex dialectic of «classical» and «modern.» The essay deals with the most recent manifestations of avant-garde aesthetic impulses. It emphasizes the historical and social aspects of German theorizing in contrast to purely formalist or ahistorical conceptions commonly found elsewhere. It insists that such «materialist» theory does greater justice than formalist conceptualizations to the proverbial connections of «art» and «life.» It tries to integrate the present phenomenon of proliferating theory into the theoretical exposition, as a characteristic trait of the current situation. It warns against abandoning the subversive content of classical modernism in the course of developing a theory of post-modernism.

  14. The Materiality of a Contemporary Avant-Garde?

    DEFF Research Database (Denmark)

    Paldam, Camilla Skovbjerg

    2013-01-01

    Collage is one of the most influential and persistent inventions of the historical avant-garde. From being a new and provoking technique in the beginning of the 20th century it is now everywhere in both art and mass culture. Some of the ways collage is used today are strongly connected with the h......Collage is one of the most influential and persistent inventions of the historical avant-garde. From being a new and provoking technique in the beginning of the 20th century it is now everywhere in both art and mass culture. Some of the ways collage is used today are strongly connected...... with the historical avant-garde, but often with significant displacements in technique, material or concept. In this paper I want to focus on legacies of surrealist collage in contemporary art. In contrast to cubist and dadaist collage the effect of surrealist collage generally relied more on semantic clashes...... the paintings by Magritte and Dali that ”the images are collages all painted by hand” (Ernst 1970, 266) . My paper pursues this kind of collage technique in contemporary art by investigating three current tendencies: One that embraces monstrous objects obviously made in one piece, but with a metaphorical...

  15. Martin Puchner, Poetry of the Revolution. Marx, Manifestos, and the Avant-Gardes 2006.

    Directory of Open Access Journals (Sweden)

    Hubert van den Berg

    2007-05-01

    Full Text Available The genre of the manifesto belongs to the key elements of avant-garde textuality. As such, the manifesto has received considerable attention in recent avant-garde research. Many articles, chapters in general studies on the avant-garde, several collections of essays, monographs and annotated anthologies have been devoted to the manifesto in the past decades. Martin Puchner's book on the avant-garde manifesto is a latecomer in this context, published some ten years after a wave of Manifestantismus struck in particular continental European avant-garde research. As in the case of any late arrival, the main question is self-evidently: what adds Puchner to already existing literature? The answer must be rather ambivalent. Puchner's book definitely fills a lacuna in the Anglophone historiography of the avant-garde.

  16. A Cultural History of the Avant-Garde in the Nordic Countries 1900-1925

    DEFF Research Database (Denmark)

    The first publication to deal with the avant-garde in the Nordic countries at the start of the twentieth century. It is the first major historical work to consider the Nordic avant-garde in a transnational perspective which includes all the arts and to discuss the role of the avant-garde not only...... within the aesthetic field, but in a broader cultural context...

  17. Nordic game subcultures: between LARPers and avant-garde

    Directory of Open Access Journals (Sweden)

    Mathias Fuchs

    2014-03-01

    Full Text Available This article is about structural resemblances, linguistic and rhetoric similarities and media-strategic as well as tactical operations, that Nordic LARPers and 20th century avant-garde artists share. Many of the 20th century avant-garde movements and subcultural formations started from a shared collective experience and then branches out into refined, diversified and individualized forms of expression. Futurism, DADA and Fluxus, Punk, Emo and Goth did originally constitute a dress code, a toolset, a jargon, a mission statement and a territorial assignment within the cities they choose as the center of their activities. Manifestos defined what a Futurist, Dadaist or Punk would most probably think and say, and how he or she would say it. A similar observation can be made for the communities that engage with live action role playing games (LARPs in the Nordic countries. The Turku manifesto and the Dogma 99 manifesto influenced directly and indirectly how the Nordic LARP subculture framed defined itself and presented itself to the world. The initiating, collective experiences of Cafe Voltaire, the Wuppertal art galleries, SOHO, and respective locations for Nordic LARPers have been constitutive for the process of identity building and identity shaping for artists and gamers alike.

  18. Leśmian’s avant-garde grandson

    Directory of Open Access Journals (Sweden)

    Agata Stankowska

    2009-01-01

    Full Text Available The sketch discusses the “relations and interdependencies of impossibilities” connecting the discursive poetry of Bieńkowski with the lyrical poetics of Leśmian. This formula, coined by the author of Sprawy wyobraźni, perfectly expresses these kind of references that exceed just a simple juxtaposition of similarities in subject matters or poetical figures. In terms of this plane, there seem to be are more differences between the two poems than conceivable similarities. However, within the plane of creative philosophy, the awareness of the language status in modern poetry, the abiding concept of reality and the attitude towards civilizational and social transformations, the similarities are particularly striking. The avant-garde poet does not shun from employing early modernist individualistic, idealistic, regressive and aesthetic (formalistic tendencies so characteristic for Leśmian. If Przyboś, as Łapiński put it, “rehabilitated” Leśmian’s programme, Bieńkowski makes the Przyboś’ programme back again more like Leśmian-like, creating a programme not so much avant-garde in character but rather a one that relates to decadent aspirations of modernism in its narrowest sense. Not surprisingly then, he makes the lyrics of the author of Łąka his particular tertium comparationis of the phenomena in Polish postwar poetry, linguistic poetry in particular. This way, unusual power of modernity of Leśmian poetry is testified and well proven.

  19. Chinese Avant-garde Art in the Late Twentieth Century

    Directory of Open Access Journals (Sweden)

    Nataša Vampelj Suhadolnik

    2014-12-01

    Full Text Available The main topic of the present paper is the '85 Art Movement, which was the first significant nationwide Avant-garde art movement in China. This movement, which arose in the mid-80s, defined the aesthetic foundations and identity of contemporary Chinese art, and represented Chinese globalized society on the threshold of the 21st century. Whilst focusing on China’s specific cultural and political contexts, the present paper analyses the concepts of humanism (renwen 人文 and idea (guannian 觀念. The spirit of humanism, with a rationalist connotation, and the desire for a revolution of ideas were the two main factors underpinning the Chinese Avant-garde movement and its artistic expressions. The paper also shows that the '85 Art Movement did not stem solely from the socio-political challenges of the 1980s, but should be regarded in the wider context of the “modernization project of Chinese art”, in the early 20th century.

  20. A Cultural History of the Avant-Garde in the Nordic Countries 1950-1975

    DEFF Research Database (Denmark)

    A Cultural History of the Avant-Garde in the Nordic Countries 1950-1975 is the first publication to deal with the postwar avant-garde in the Nordic countries. The essays cover a wide range of avant-garde manifestations in arts and culture: literature, the visual arts, architecture and design, fil......: The cultural politics, institutions and new cultural geographies after World War II, new technologies and media, performative strategies, interventions into everyday life and tensions between market and counterculture.......A Cultural History of the Avant-Garde in the Nordic Countries 1950-1975 is the first publication to deal with the postwar avant-garde in the Nordic countries. The essays cover a wide range of avant-garde manifestations in arts and culture: literature, the visual arts, architecture and design, film......, radio, television and the performative arts. It is the first major historical work to consider the Nordic avant-garde in a transnational perspective that includes all the arts and to discuss the role of the avant-garde not only within the aesthetic field but in a broader cultural and political context...

  1. Art-House Cinema, Avant-Garde Film, and Dramatic Modernism

    Science.gov (United States)

    Cardullo, Bert

    2011-01-01

    In this article, the author talks about art-house cinema, avant-garde film, and dramatic modernism. He believes that the most important modes of film practice are art-house cinema and the avant-garde, both of which contrast with the classical Hollywood mode of film practice. While the latter is characterized by its commercial imperative, corporate…

  2. Pursuing the Administrative Avant-Garde: An Aesthetic Critique of Change in Educational Systems

    Science.gov (United States)

    Samier, Eugenie A.

    2012-01-01

    This paper addresses theories of the avant-garde, especially but not exclusively in art and as part of a modernist aesthetic. The paper examines the ways in which avant-garde theory of the creative process can inform educational administration in the change process, as both a critique and an ideal. The argument adopted here is that if…

  3. "Nothing is Certain": Czech Post-War Literature Between the Avant-Garde and Expressionism

    Czech Academy of Sciences Publication Activity Database

    Říhová, Zuzana

    2016-01-01

    Roč. 14, č. 2 (2016), s. 125-140 ISSN 1479-0963 Institutional support: RVO:68378068 Keywords : collectivism, individualism, avant-garde, expressionism, Czech literature, short fiction, anxiety, fear, anthropomorphization * individualism * avant-garde * expressionism * Czech literature * short fiction * anxiety * fear * anthropomorphization Subject RIV: AJ - Letters, Mass-media, Audiovision

  4. Cosmologie l'univers avant le Big Bang

    CERN Multimedia

    Larousserie, David

    2003-01-01

    Tout n'a pas commencé par une explosion. L'histoire du cosmos avait débuté bien avant le Big Bang, si l'on suit la théorie défendue par les partisans d'une nouvelle cosmologie issue de la mystérieuse théorie des cords. A l'heure où vacillent les scénarios classiques du XXe siècle, se prépare un grand chamboulement de nos idées sur la naissance de l'Univers et son devenir, sur l'existence possible d'univers parallèles.

  5. Towards a "reconciliation of man and nature" - Nature and ecology in the aesthetic avant-garde of the twentieth century

    NARCIS (Netherlands)

    Van Den Berg, Hubert F.; Hopkins, D

    2006-01-01

    Avant-garde art is often regarded as a turn away from nature, due both to the rejection of conventional mimesis and to the special predilection of the avant-garde for technology and metropolitan life. Whereas some sections of the avant-garde might indeed have been "anti-nature", one can also observe

  6. Exito para el XVI Festival Internacional de Teatro Hispano del Teatro Avante

    National Research Council Canada - National Science Library

    Marrero, Teresa

    2002-01-01

    Highlights the 16th Festival Internacional de Teatro Hispano, which was held June 1-17, 2001, at the Teatro Avante in Miami, Florida, and subsequently June 20-30 at the Duke Theatre of the New 42nd...

  7. Defying the Avant-Garde Logic: Architecture, Populism, and Mass Culture

    National Research Council Canada - National Science Library

    Dirk van den Heuvel; Tahl Kaminer

    2014-01-01

    As an introduction to this issue of Footprint, which is dedicated to questions pertaining to the role, perception and valuation of mass culture and populism within the twentieth century, avant-garde...

  8. Romanticism, the Avant-Garde, and the Early Modern Innovators in Arts Education.

    Science.gov (United States)

    Leeds, Jo Alice

    1985-01-01

    The contributions of major avant-garde innovators, e.g., Cizek, Jaques-Dalcroze, Laban, Lowenfeld, Orff, Kodaly, and Mearns, who worked to establish the creative process as an important means of human education are discussed. (RM)

  9. Beyond the Score: Timbre Analysis in Avant-garde Music

    Directory of Open Access Journals (Sweden)

    Mario Baroni

    2016-02-01

    Full Text Available The article examines perceptual aspects of timbre within the context of avant-garde XX century music. An excerpt from a work by Luciano Berio was taken into account. We recorded it on 8 separate channels each of them devoted to small groups of homogeneous sounds, in order to obtain a global result that we could modify by subtracting one or more of the recorded groups. We prepared four different excerpts: one with the original version and three with modified versions. 50 participants (25 experts, 25 non-experts were invited to fill in a semantic differential bipolar scale made of 12 adjectives, 6 concerning emotional and 6 sensorial aspects of perception. We interpreted the subjects’ responses with the help of a spectrographic analysis and of studies on timbre verbalization. The main aim of our research was to explore the possibilities of timbre analysis, a field that so far has no solid scientific background. The research obtained promising responses from expert listeners, while non-experts manifested a sort of aesthetic refusal of this genre of music. Positive results were obtained also in the critical observations of possibilities and limits of spectrographic analysis and verbalizations of timbre. We hope that our initial data can be useful for future studies on timbre perception.

  10. What is the avant-garde? The questionnaire as historiography

    Directory of Open Access Journals (Sweden)

    Lori Cole

    2011-12-01

    Full Text Available In 1928 the Cuban magazine Revista de Avance issued a questionnaire asking, ‘What should (Latin American art be?’ while the same year the expatriate magazine transition based in Paris, polled its North American contributors asking: ‘Why do Americans Live in Europe?’ and surveyed its European writers to ask: ‘How are the influences of the United States manifesting themselves upon Europe?’ By examining these questionnaires issued across the Atlantic in the same year, I examine the way the genre structures the artistic and political stakes of modernist print communities and illuminates the relationships these magazines establish between aesthetics and the Americas. Questionnaires functioned as print proxies by implying through their reproduction of multiple individual responses a much larger community of writers and readers. Both questionnaires work to interpellate the magazines’ dispersed communities and to emphasize the effects of their dis/location on their artistic purpose, ultimately forming a patchwork historiography of the avant-garde.

  11. Ataque cerebral

    OpenAIRE

    Takeuchi Tan, Yuri; Fundación Valle de Lili

    1998-01-01

    ¿Qué es un ataque cerebral?/¿Qué tipos de ataque cerebral existen?/¿Cuáles son los síntomas de un ataque cerebral?/Factores de riesgo para un ataque cerebral/Tratamiento médico del ataque cerebral/¿por qué es importante acudir temprano cuando se presentan las señales de alarma?/ Manejo preventivo del ataque cerebral isquémico/Tratamiento quirúrgico del ataque cerebral/Enfermedad vascular cerebral hemorrágica/¿Cómo está constituido el grupo de ataque cerebral de la fundación Clínica Valle d...

  12. Defying the Avant-Garde Logic: Architecture, Populism, and Mass Culture

    Directory of Open Access Journals (Sweden)

    Dirk van den Heuvel

    2014-08-01

    Full Text Available As an introduction to this issue of Footprint, which is dedicated to questions pertaining to the role, perception and valuation of mass culture and populism within the twentieth century, avant-garde discourse, this text presents a tentative framework that contextualizes and elaborates the questions at hand. It argues that the specific negotiation in the late twentieth century between the architecture discipline and the phenomenon of the consumer society, and especially mass media technologies, introduced a new, hybrid, and at times contradictory disciplinary discourse and practice, which defies the historic avant-garde logic as described by Peter Bürger. The editors argue that the re-investigations of the late twentieth century avant-garde vis-à-vis mass culture lead to a better understanding of the challenges contemporary architecture faces.

  13. La culture visuelle de la science-fiction, entre culture populaire et avant-garde

    OpenAIRE

    Achouche, Mehdi; Besson, Anne; Besson, Cyril; Bréan, Simon; Chauvin, Cédric; Delbouille, Julie; Dutel, Jérôme; Freedman, Carl; Genefort, Laurent; Langlet, Irène; Limousin, Isabelle; Minne, Samuel; Ray, Alice; Reymond, Guillaume; Smet, Elsa De

    2014-01-01

    La culture populaire comme l’avant-garde ont suscité des études riches et spécifiques. En faisant dialoguer des spécialistes des deux pôles, ce numéro explore comment, dans les images de la science-fiction, la culture populaire et, à travers l’avant-garde même, toutes les formes d’académisme, même oxymoriques, s’éclairent réciproquement.

  14. Cerebral Palsy

    Science.gov (United States)

    Cerebral palsy is a group of disorders that affect a person's ability to move and to maintain balance ... do not get worse over time. People with cerebral palsy may have difficulty walking. They may also have ...

  15. Cerebral malaria Malaria cerebral

    Directory of Open Access Journals (Sweden)

    Silvia Blair Trujillo

    2003-03-01

    Full Text Available Is the most common complication of P. falciparum malaria; nearly 90% of people who have suffered CM can recover without neurological problems. Currently there are four hypotheses that explain pathogenesis of CM: cytoadherence and sequestering of parasitized red blood cells to cerebral capillaries; rosette formation and parasitized red blood cells agglutination; production of cytokines and activation of second messengers and opening of the blood-brain barrier. However the main question remains to be answered; how the host-parasite interaction in the vascular space interferes transiently with cerebral function? Recently, the beta amyloid precursor peptide has been employed as marker of neural injury in CM. It is expected that the beta amyloid precursor peptide will help to understand the pathogenesis of CM in complicated patients of endemic areas of Colombia. La malaria Cerebral (MC es la complicación más frecuente de la malaria por P. falciparum; aproximadamente el 90% de las personas que la han padecido se recuperan completamente sin secuelas neurológicas. Aún no se conoce con claridad su patogénesis pero se han postulado cuatro hipótesis o mecanismos posibles: 1 citoadherencia y secuestro de glóbulos rojos parasitados en la microvasculatura cerebral; 2 formación de rosetas y aglutinación de glóbulos rojos parasitados; 3 producción de citoquinas y activación de segundos mensajeros y, 4 apertura de la barrera hematoencefálica. Sin embargo, queda un interrogante sin resolver aún: ¿qué proceso se lleva a cabo para que el parásito, desde el espacio microvascular, pueda interferir transitoriamente con la función cerebral? Recientemente se ha utilizado el precursor de la proteína b-Amiloide como un marcador de daño neuronal en MC; este precursor será de gran ayuda en futuras investigaciones realizadas en nuestro medio que aporten información para comprender la patogénesis de la MC.

  16. (disFunctions: Marxist Theories of Architecture and the Avant-garde

    Directory of Open Access Journals (Sweden)

    Michael Chapman

    2014-01-01

    Full Text Available This paper investigates the relationship between architecture and theories of the avant-garde in the critical projects of the 1970s, with a focus on the theories of Peter Bürger and Manfredo Tafuri. Both Tafuri and Bürger were writing from within the context of a radicalized Marxism and were fuelled by an intellectual pessimism towards the totalizing systems of cultural production that questioned the role of resistance in aesthetics and the inability of the historical avant-gardes to engage within the political and economic fields of contemporary society. While there is a common ancestry to these two approaches, and mutual acceptance of the failure of the avant-garde project, the work of Tafuri has had an enduring influence on architectural history and theory, while Bürger’s synchronous work has attracted only a modest amount of scholarly attention in architecture despite its ongoing legacy in art theory and, particularly, within an American context. This paper argues that Bürger’s dialectical approach has a significance for architectural theory and presents a discursive position through which Marxism and architecture can be advanced. Through a detailed reading of these two approaches, the paper attempts to position architecture as a particular strategy of the avant-garde that overshadowed all fields of aesthetic production in the period.

  17. De as Brussel-Wenen 1900: De wederzijdse receptie van de Brusselse en Weense avant-garde in vier tijdschriften

    Directory of Open Access Journals (Sweden)

    Christophe Schellekens

    2011-12-01

    Full Text Available This article investigates the mutual reception of the Brussels and Viennese avant-garde in four periodicals: the Viennese magazine Ver Sacrum and the Brussels periodicals Van Nu & Straks, L‟Art Moderne and La Jeune Belgique. Ver Sacrum, the magazine of the Secession, claimed to be the first avant-garde periodical in Vienna and this article thus deals with its reports on Belgian avant-garde artists. Van Nu & Straks is considered to be the first Flemish avant-garde journal, while L‟Art Moderne and La Jeune Belgique were two Brussels periodicals written in French. With respect to these three Brussels periodicals, this article pays particular attention to their documentation of the upcoming Viennese avant-garde. In special editions, articles and references on Belgian artists in Ver Sacrum, the lack of biographical references is the most noteworthy aspect. In L‟Art Moderne the reporting on Viennese art, artists and avant-garde institutes is very concise and mainly related to Belgian artists. Despite its interest in other artistic developments in Europe, Van Nu & Straks and La Jeune Belgique did not report on Viennese avant-gardism.

  18. Sensus communis aestheticus and the project of emancipation: The Utopian frame of the avant-gardes.

    Directory of Open Access Journals (Sweden)

    Loredana Niculet

    2011-07-01

    Full Text Available The conceptual basis which would be later developed by the artistic avant-gardes was settled by German Romantic and Idealist thought, whose utopian dimension could be easily recognized in The oldest systemprogram of German Idealism (1796, a text which provided Idealist thought with the claim of a new rationality or a mythology of reason in Hegel, an intellectual intuition in Schelling and the Humanity in Schiller. Although this emancipation project developed later by the avant-garde has lost its credibility for us, we still have to investigate to what extent today’s art can maintain a social function. This article point out certain idealist concepts in light of a philosophy of art modeled along lines sketched out in Kant’s Critique of Judgement and that have contributed to the history of the “advanced” art.

  19. Speed and Convulsive Beauty: Trains and the Historic Avant-garde

    Directory of Open Access Journals (Sweden)

    Marylaura Papalas

    2015-01-01

    Full Text Available The train, an invention and evocative symbol of the 19th century, somewhat ironically continued to fascinate avant-garde artists and writers of the 20th century, when faster and more exciting modes of transportation were in use. Locomotive imagery in Italian futurism and French surrealism, however, demonstrates a lasting fascination with speed, locomotive space, and their effect on perceptions of reality. Considering the work of more recent theorists like Paul Virilio, Michel Foucault, and various others who have contributed to the growing field of mobility studies, this paper aims to understand the persisting presence of the train as a symbol of an alternative reality in historic avant-garde work, particularly that of the Italian Futurists and the French Surrealists.

  20. Neurofibrome de l'avant bras: à propos d'un cas | Fahim | Pan ...

    African Journals Online (AJOL)

    Nous rapportons un cas de neurofibrome de l'avant bras dont la symptomatologie est souvent discrète associé à des taches café au lait sur la peau. De ce fait, l'imagerie et l'examen anatomopathologique ont une place importante dans la prise en charge de ces tumeurs. Key words: Neurofibromes, taches café au lait, ...

  1. Beyond Surrealism: Kitawaki Noboru and the Avant-Garde During Wartime Japan, 1931-1951

    OpenAIRE

    Ritter, Gabriel Richard

    2016-01-01

    This dissertation traces the life and work of the artist Kitawaki Noboru (1901-1951), utilizing his story as a case study to explore issues related to surrealism in Japan, the pressures on avant-garde expression during wartime, and the general shift from authoritarianism toward a postwar artistic subjectivity and discovery of individual autonomy. While Kitawaki’s work is often dense and idiosyncratic, bringing together obscure references from science, philosophy, and Chinese divination, his s...

  2. Participation des hommes aux soins aux enfants avant la mise en ...

    African Journals Online (AJOL)

    Participation des hommes aux soins aux enfants avant la mise en oeuvre de la composante familiale et communautaire de la stratégie «prise en charge intégrée des ... In the case of accident occurred in children, the decision of the therapeutic route came from the father in 71.4% of the cases, and the rugged child care ...

  3. ‘A Haze of Visions’: Dream Work in Early Australian Avant-Garde Cinema

    Directory of Open Access Journals (Sweden)

    Danni Zuvela

    2012-11-01

    Full Text Available Prior to the highly visible outbreak of avant-garde cinema in the 1960s, a number of earlier films made in Australia displayed broadly experimental aesthetic concerns. This essay considers these proleptic works via an analysis of the recurring motif of the dream, exploring the historical forces leading to their production, and suggests that the consonance with the aspirations of international Surrealism subtending these works had both an experimental and pragmatic agenda.

  4. Cerebral hypoxia

    Science.gov (United States)

    ... before, during, or soon after birth such as cerebral palsy Stroke Very low blood pressure Brain cells are very sensitive to a lack of ... of the eye to light Exams and Tests Cerebral hypoxia can usually be diagnosed based on the person's medical history and a physical exam. Tests are done to ...

  5. Accident vasculaire cérébral ischémique révélant une maladie coeliaque

    Directory of Open Access Journals (Sweden)

    Belfkih Rachid

    2010-04-01

    Full Text Available La maladie cœliaque (MC de l’adulte est une pathologie fréquente dont la présentation clinique est polymorphe. Les manifestations extradigestives sont multiples et rendent le diagnostic difficile lorsqu’elles sont isolées. Nous rapportons le cas d’un patient de 52 ans qui présentait un accident vasculaire cérébral ischémique (AVCI. Le bilan étiologique objectivait une hyperhomocystéinémie avec une carence en vitamine B12. La biopsie duodénale était en faveur d’une maladie coeliaque. Les anticorps antigliadines étaient positifs. Le patient fût mis sous régime sans gluten, anti-aggrégant plaquettaire et hydroxocobalamine avec une évolution favorable.

  6. Accuracy of the Siriraj Stroke Score in Differentiating Cerebral ...

    African Journals Online (AJOL)

    scan, Accident vasculaire cérébral hemorragique, Accident vasculaire cérébral ischémique, A frique, Nigeria, tomodensitométrie. Résumé Introduction Dans le but d\\'agir avec efficacité dans la prise en charge thérapeutique des accidents ...

  7. Cerebral palsy

    Science.gov (United States)

    ... people who are affected by cerebral palsy) Social stigma When to Contact a Medical Professional Call your ... chap 598. Nass R, Sidhu R, Ross G. Autism and other developmental disabilities. In: Daroff RB, Jankovic ...

  8. Cerebral Aneurysms

    Science.gov (United States)

    ... Page NINDS Cephalic Disorders Information Page NINDS Cerebral Cavernous Malformation Information Page NINDS Chronic Pain Information Page ... Information Page Adrenoleukodystrophy Information Page Agenesis of the Corpus Callosum Information Page Agnosia Information Page Aicardi-Goutieres ...

  9. Cerebral Paragonimiasis.

    Science.gov (United States)

    Miyazaki, I

    1975-01-01

    The first case of cerebral paragonimiasis was reported by Otani in Japan in 1887. This was nine years after Kerbert's discovery of the fluke in the lungs of Bengal tigers and seven years after a human pulmonary infection by the fluke was demonstrated by Baelz and Manson. The first case was a 26-year-old man who had been suffering from cough and hemosputum for one year. The patient developed convulsive seizures with subsequent coma and died. The postmortem examination showed cystic lesions in the right frontal and occipital lobes. An adult fluke was found in the occipital lesion and another was seen in a gross specimen of normal brain tissue around the affected occipital lobe. Two years after Otani's discovery, at autopsy a 29-year-old man with a history of Jacksonian seizure was reported as having cerebral paragonimiasis. Some time later, however, it was confirmed that the case was actually cerebral schistosomiasis japonica. Subsequently, cases of cerebral paragonimiasis were reported. However, the majority of these cases were not confirmed histologically. It was pointed out that some of these early cases were probably not Paragonimus infection. After World War II, reviews as well as case reports were published. Recently, investigations have been reported from Korea, with a clinicla study on 62 cases of cerebral paragonimiasis seen at the Neurology Department of the National Medical Center, Seoul, between 1958 and 1964. In 1971 Higashi described a statistical study on 105 cases of cerebral paragonimiasis that had been treated surgically in Japan.

  10. Transmental Sheherazade on the interwar avant-garde balls in Belgrade and Paris

    Directory of Open Access Journals (Sweden)

    Jović Bojan

    2013-01-01

    Full Text Available In expert circles, attention has been drawn to the “1002nd Night Ball” created by the protagonists of Yugoslav and Serbian avant-garde, in particular on its dance and musical segments, moreover, the ballet “Le balai du valet” by Marko Ristić and Miloje Milojević, as well as the ensuing series of balls related to the Association of Friends of Art “Cvijeta Zuzorić”. On the other hand, it is an (almost completely unknown fact that Rade Drainac’s original idea to throw a ball for the benefit of artists and writers that needed financial assistance because of difficult financial situation (later replaced with an initiative to raise funds to build an art pavilion “Cvijeta Zuzorić” matched the idea of the Union of Russian artists in Paris to organize a ball with the aim of contributing to mutual aid. The ball in Paris, with the participation of the most prominent avant-garde artists, took place exactly one week after the Belgrade ball, which also suggests the possible connection / synchronization of these two artistic events. Having this in mind, I offer a brief analysis of the concept and scope of the aforementioned artistic events from the perspective of the intermedia and multimedia strategies. I demonstrate that the Belgrade spectacle was envisioned and performed far more ambitiously than the Parisian one, and the thoroughness of the interweaving of various arts ranks it among those works (including Parade by Cocteau, Picasso and Satie, Skating-Rink by Canudo, Leger, and Honegger, La creation du monde by Cendrars, Léger and Milhaud, with Russian and Swedish Ballet that aimed to achieve a Gesamtkunstwerk, i.e. a total work of avant-garde art. [Projekat Ministarstva nauke Republike Srbije, br. ON 178008: Srpska književnost u evropskom kulturnom prostoru

  11. Cerebral Palsy (For Teens)

    Science.gov (United States)

    ... Situations Talking to Your Parents - or Other Adults Cerebral Palsy KidsHealth > For Teens > Cerebral Palsy Print A A ... do just what everyone else does. What Is Cerebral Palsy? Cerebral palsy (CP) is a disorder of the ...

  12. The Russian avant-garde painting palette--documentary and physicochemical study of inorganic colorants.

    Science.gov (United States)

    Kampasakali, Elli; Papliaka, Zoe Eirini; Christofilos, Dimitirios; Varella, Evangelia A

    2007-07-01

    In the present article an attempt is being made to elucidate the inorganic colorants encountered in the Russian avant-garde painting palette by a combined art historical, documentary and physicochemical investigation; and to examine the influence of environmental factors on the chromatic profile originally sought by the artist. The overall approach based on written sources is confirmed by measurements on representative paintings from the Costakis Collection in the State Museum for Contemporary Art, Thessaloniki. The documentary research deals with the influences of Orthodox iconography, folkloric art, and occidental modernist tendencies on the Russian avant-garde palette; and is studying the effects of contradictory historical processes in the chromatic profile of individual paintings. In the experimental section a series of colorants are investigated concerning the effects of accelerated ageing on experimental painting tables, prepared as watercolour and gouache layers on paper ground. The resulting samples are subject to colorimetric, and spectroscopic measurements; and analogous analytical procedures are applied on samples taken from selected paintings belonging to the Costakis Collection. A systematic comparative study of all data permits evaluating the materials used as to their stability towards exstrincic factors, and proposing degradation routes, in order to assist museum curators and conservators in every concrete case related to the broad spectrum of pigments examined.

  13. Einstein and early 20th Century avant-garde art: points of contact?

    CERN Document Server

    Martini, José X

    2007-01-01

    Art history linked some early 20th Century avant-garde visual art movements to contemporary systems of ideas in mathematics and theoretical physics. One of the proposed connections is the one that might have existed between Cubism and Relativity, or more precisely, between Picasso and Einstein. The suggested links are similarity (in a weak version) or identity (in a strong version) in matters of space, time and simultaneity. It is possible, however, that these supposed links of Einstein and avant-garde art movements were more the product of the imagination of historians and critics, than the result of connections between painters and scientists. On the one hand, the visual arts (in contrast to music, as far as we now) were of no interest to Einstein, who, moreover, did not seem inclined or knowledgeable enough to appreciate advanced forms. On the other hand, Einstein's theories fell outside the artists' ken, let alone their understanding, although there are firm clues pointing to the fact that repercussions o...

  14. BRECHT'S EPIC THEATRE AS A MODERN AVANT-GARDE AND ITS INFLUENCE ON POSTMODERN THEATRE/DRAMA

    OpenAIRE

    Ribut Basuki

    2002-01-01

    As one of the most influential figures in theatre, Bertolt Brecht has stamped his legacy in the world theatre. His search for a new kind of theatre made his theatre a modern avant-garde which has left its traces in postmodern theatres. This paper tries to investigate Brecht's epic theatre as a modern avant-garde and its influence in postmodern theatre. His epic theatre was in fact a revolt against the main stream modern theatre in which Brecht openly declares that theatre should be 'pol...

  15. BRECHT'S EPIC THEATRE AS A MODERN AVANT-GARDE AND ITS INFLUENCE ON POSTMODERN THEATRE/DRAMA

    OpenAIRE

    Ribut Basuki

    2002-01-01

    As one of the most influential figures in theatre, Bertolt Brecht has stamped his legacy in the world theatre. His search for a new kind of theatre made his theatre a modern avant-garde which has left its traces in postmodern theatres. This paper tries to investigate Brecht's epic theatre as a modern avant-garde and its influence in postmodern theatre. His epic theatre was in fact a revolt against the main stream modern theatre in which Brecht openly declares that theatre should be 'political...

  16. Un accident vasculaire hémorragique révélant une méningite à Neisseria meningitides

    Science.gov (United States)

    Savadogo, Mamoudou; Millogo, Georges Rosario Christian; Zabsonré, Sylvain

    2015-01-01

    L'accident vasculaire hémorragique et la méningite purulente constituent des urgences médicales chez la personne âgée. L'Objectif est de rapporter un cas d'accident vasculaire hémorragique associé à une méningite purulente à Neisseria meningitidis survenus chez une personne âgée. Il s'agit d'une patiente de 62 ans sans antécédent pathologique connu, a été admise aux urgences médicales du CHU YO pour céphalées + vomissement et notion de perte brutale de connaissance. L'examen à son admission notait un syndrome infectieux, une conscience obnubilée sans déficit moteur, une raideur cervicale et une hypertension artérielle. La tomodensitométrie cérébrale avait objectivé une hémorragie méningée diffuse avec inondation du 4ème ventricule responsable d'une hydrocéphalie triventriculairesous jacente d'allure obstructive associée à des sinusites ethmoïdo-sphénoïdales droites chroniques. Une ponction lombaire réalisée avait montré un liquide cérébrospinal citrin dont l'analyse était en faveur d'une méningite purulente à méningocoque. La glycémie était élevée à 15,8 mmol/l et l'hémoglobine glyquée était égale à 7,7%. L’évolution a été favorable sous traitement à base de ceftriaxone et de Metformine. Devant un cas suspect de méningite chez une personne âgée, la ponction lombaire après un TDM cérébral permet de poser le diagnostic et d'entreprendre rapidement une antibiothérapie indispensable pour la prévention des complications. PMID:26097638

  17. Aspects épidémiologiques des accidents vasculaires cérébraux (AVC) aux urgences de l'institut de cardiologie d'Abidjan (ICA)

    Science.gov (United States)

    N'goran, Yves N'da Kouakou; Traore, Fatou; Tano, Micesse; Kramoh, Kouadio Euloge; Kakou, Jean-Baptiste Anzouan; Konin, Christophe; Kakou, Maurice Guikahue

    2015-01-01

    Introduction L'objectif de notre étude était de décrire les caractéristiques sociodémographiques et les Facteurs de Risque cardio-Vasculaires (FRV) des patients admis pour accidents vasculaires cérébraux (AVC) dans un service autre que celui de la neurologie. Méthodes Étude transversale rétrospective sur une période de 2 ans (janv. 2010 et déc. 2011), réalisée aux urgences de l'institut de cardiologie d'Abidjan. Résultats Il s'agissait de 176 adultes avec un âge moyen de 60 ans, une prédominance féminine. Les facteurs de risque majeurs retrouvés étaient l'hypertension artérielle dans 86,4% des cas, le diabète dans 11,4% des cas, le tabagisme dans 2,2% des cas. Les motifs de consultation étaient la perte de connaissance dans 36,4% des cas, l'hémiplégie dans 31,8% des cas, les céphalées dans 17,4% des cas, les vertiges dans 10,9% et les palpitations dans 2,2% des cas. La tension artérielle systolique moyenne était à 174 mmHg, la tension artérielle diastolique moyenne était à 105 mmHg et la pression pulsée moyenne était à 70 mmHg. Les AVC étaient associés à une arythmie complète par fibrillation auriculaire dans 11,4% des cas. Les AVC ischémiques représentaient 84,1%. L’évolution aux urgences a été marquée par un décès dans 17% (30) des cas. Conclusion Les AVC constituent un problème majeur de santé publique. Malgré sa prédominance féminine, ils (AVC) touchaient 44% des hommes dans notre étude lorsqu'on sait qu'en Afrique l'activité sociale repose sur les hommes. Ils restent une pathologie grave par la forte létalité. PMID:26327997

  18. Schumpeter: Theorist of the Avant-Garde : The embrace of the new in Schumpeter’s original theory of economic development

    NARCIS (Netherlands)

    E. Dekker (Erwin)

    2017-01-01

    textabstractThis paper argues that Schumpeter’s 1911 edition of ‘Theory of Economic Development’ can be fruitfully read as a theory of the avant-garde, in line with such theories developed by artistic avant-garde around the same time, in particular by the Italian Futurists. In particular it will

  19. Fractures diaphysaires déplacées de l'avant-bras chez l'enfant ...

    African Journals Online (AJOL)

    Mots clés : fractures avant-bras, enfant, traitement orthopédique. The aim of this study was to assess the outcome of the orthopedic management of displaced diaphyseal forearm fractures in children. Fiftysix patients were treated for displaced diaphyseal fractures of the forearm between january 2009 and june 2010.

  20. From material science to avant-garde cuisine. The art of shaping liquids into spheres.

    Science.gov (United States)

    Fu, Haohao; Liu, Yingzhe; Adrià, Ferran; Shao, Xueguang; Cai, Wensheng; Chipot, Christophe

    2014-10-09

    Employing avant-garde cuisine techniques, in particular sodium alginates, liquid food can be shaped into spheres, thereby conferring to the former original and sometimes unexpected forms and textures. To achieve this result, rational understanding of the science that underlies food physical chemistry is of paramount importance. In this contribution, the process of spherification is dissected for the first time at the atomic level by means of classical molecular dynamics simulations. Our results show that a thin membrane consisting of intertwined alginate chains forms in an aqueous solution containing calcium ions, thereby encapsulating in a sphere the aliment in its liquid state. They also show why the polysaccharide chains will not cohere into such a membrane in a solution of sodium ions. Analysis of the trajectories reveals the emergence of so-called egg-box spatial arrangements, which connect the alginate chains by means of repeated chelation of one calcium ion by two carboxylate groups. Free-energy calculations delineating the formation of these egg-box structures further illuminate the remarkable stability of such tridimensional organizations, which ensures at room temperature the spontaneous growth of the polysaccharide membrane. Spherification has been also examined for liquid aliments of different nature, modeled by charged, hydrophilic and hydrophobic compounds. The membrane-encapsulated food is shaped into robust and durable spheres, irrespective of the liquid core material. By reconciling the views of spherification at small and large scales, the present study lays the groundwork for the rational design of innovative cooking techniques relevant to avant-garde cuisine.

  1. United Cerebral Palsy

    Science.gov (United States)

    ... your local affiliate Find your local affiliate United Cerebral Palsy United Cerebral Palsy (UCP) is a trusted resource for individuals with Cerebral Palsy and other disabilities and their networks. Individuals with ...

  2. Employees with Cerebral Palsy

    Science.gov (United States)

    ... Resources Home | Accommodation and Compliance Series: Employees with Cerebral Palsy (CP) By Eddie Whidden, MA Preface Introduction Information ... SOAR) at http://AskJAN.org/soar. Information about Cerebral Palsy (CP) What is CP? Cerebral palsy is a ...

  3. Accident vasculaire cérébral hémorragique du tronc cérébral suite à une éclampsie du post partum: à propos d’un cas et revue de la littérature

    OpenAIRE

    Ennaqui, Khadija; Makayssi, Assia; Boufettal, Houssine; Samouh, Naima

    2017-01-01

    Les accidents vasculaires cérébraux sont des accidents rares mais graves durant la grossesse et le post-partum, ils sont responsable d'une mortalité et d'une morbidité élevée, la pré éclampsie, l'éclampsie et les accidents vasculaires cérébraux sont significativement liés. Le dysfonctionnement endothélial, l'altération de l'autorégulation cérébrale, et l'hypertension sévère sont, probablement, la cause de nombreux accidents vasculaires cérébraux chez la femme enceinte et durant la période du ...

  4. La programmmation foetale de la dysfonction vasculaire pulmonaire chez la souris : rôle des mécanismes épigénétiques = Fetal programming of pulmonary vascular dysfunction in mice : role of epigenetic mechanisms

    OpenAIRE

    Rexhaj, E.

    2011-01-01

    Rapport de synthèseDes événements pathologiques survenant pendant la période foetale prédisposent la descendance aux maladies cardiovasculaires systémiques. Il existe peu de connaissances au sujet de la circulation pulmonaire et encore moins quant aux mécanismes sous-jacents. La sous-alimentation maternelle pendant la grossesse peut représenter un modèle d'investigation de ces mécanismes, parce que chez l'animal et l'homme elle est associée à une dysfonction vasculaire systémique chez la prog...

  5. Incidence des accidents vasculaires cérébraux chez les patients VIH positifs sous traitement antirétroviral au long court

    Science.gov (United States)

    Mapoure, Yacouba Njankouo; Nkongni, Ines Nepetsoun; Luma, Henry Namme; Ngahane, Bertrand Hugo Mbtachou; Barla, Esther; Ngwane, Samuel; Mouelle, Albert Soné; Njamnshi, Alfred Kongnyu

    2016-01-01

    Introduction Avec l'introduction de la trithérapie dans les années 1996, la morbidité et la mortalité liées à l'infection par le VIH a nettement diminué. Concomitamment avec ce succès clinique, plusieurs changements métaboliques incluant diabète, hypertension artérielle, dyslipidémie et lipodystrophie ont été observés, ceux-ci étant des pourvoyeurs d'accidents vasculaires cérébraux. L'objectif de ce travail était de déterminer l'incidence des accidents vasculaires cérébraux chez les patients VIH positifs sous traitement antirétroviral au long court. Méthodes Il s'agissait d'une étude de cohorte rétrospective, menée dans le Centre de Traitement Agrée de l'Hôpital Général de Douala (HGD), avec un recueil des données sur 10 ans allant de Mai 2001 à avril 2010, portant sur les patients VIH positifs adultes sous traitement antirétroviral depuis au moins 6 mois. Les patients étaient suivis selon le protocole national de prise en charge du Cameroun. La survenue d'un AVC a été déterminée par la méthode Kaplan-Meyer tandis que les facteurs associés à la survenue d'un AVC ont été recherché par le test de Khi-2. Le seuil de signification statistique était fixé à 0,05. Résultats 307 patients étaient inclus dont 62,4% de sexe féminin, et l’âge moyen était de 40,1 ± 9,9 ans. L'incidence des AVC était de 1,7% sur 72 mois de suivi sans différence significative entre les femmes et les hommes (P= 0,76). Le taux d'incidence calculé était de 0,3 pour 100 personnes années. Dans 85,7% des cas il s'agissait d'un AVC ischémique. Le délai moyen de survenue d'un AVC était de 33,4 mois. Les facteurs associés à la survenue d'un AVC étaient: les patients ayant initié leur traitement au stade III et IV de l'OMS et le taux de CD4 > 100/mm3 à l'initiation du traitement antirétroviral. Conclusion L'incidence des AVC chez les patients VIH positifs sous traitement antirétroviral est similaire à celle rapportée ant

  6. Developing a social media marketing strategy for the horse industry customer group : Case: Avant Tecno UK LTD

    OpenAIRE

    Tantsurina, Anna

    2017-01-01

    The purpose of this thesis was to develop social media marketing plan and implementation steps for Avant Tecno UK LTD. The aim was to identify the most suitable online media channels, types and forms of content as well as techniques for reaching horse industry customer group via social media channels in the most efficient way. Various research methods were used to reach different objectives of the thesis. The empirical study was conducted as a quantitative research by means of in-person, ...

  7. La formation des ingénieurs électrotechniciens au Canada avant la Première Guerre mondiale

    NARCIS (Netherlands)

    Auger, J.F.

    2006-01-01

    Résumé : La formation des ingénieurs électrotechniciens débuta au cours de la Seconde Révolution industrielle (1880-1920) en Europe et en Amérique du Nord. Ce chapitre examine l’établissement du génie électrique au Canada avant la Première Guerre mondiale. Il démontre l’influence de la politique

  8. Un système d'avant-garde rend l'accès à l'information abordable ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 oct. 2010 ... Des organismes d'une soixantaine de pays se servent encore aujourd'hui d'un système d'avant-garde conçu dans les années 1970 par le CRDI pour emmagasiner, gérer et récupérer des données sur le développement.

  9. Lin Xiaoping, Children of Marx and Coca-Cola. Chinese Avant-garde art and independent cinema

    OpenAIRE

    Dubouloz, Aurelia

    2012-01-01

    Xiaoping, currently associate professor at Queens College, New York, says in his introduction that he lived in China before moving to the United States, where he obtained a doctorate in 1993 at Yale. His book, second in the Critical Interventions series published by the University of Hawaii, offers a complementary study of the artistic avant-garde and of independent Chinese cineastes against the background of a post-socialist China in the throes of capitalist globalisation. Lin focuses his st...

  10. Vladimir Levstik et la langue française avant 1941

    Directory of Open Access Journals (Sweden)

    Florence Gacoin-Marks

    2005-12-01

    Full Text Available En Slovénie, Vladimir Levstik (1886-1957 est aujourd'hui surtout connu comme un traducteur des littératures anglaise, française et russe particulièrement fecond, ayant traduit au total près d'une centaine d'reuvres. Parmi toutes ces traductions ayant souvent connu plusieurs reimpressions ou rééditions, une soixantaine sont parues avant la seconde guerre mondiale, à la période où Levstik est également très actif en tant qu'écrivain. Cette activité de traducteur très intensive n'est done pas seulement intéressante en elle-même: transmetteur ayant permis aux lecteurs slovènes d'accéder aux plus grands chefs-d'reuvre du patrimoine littéraire (en parti­ culier romanesque européen, Vladimir Levstik doit être également envisager en tant que lecteur et récepteur privilégié des littératures européennes.

  11. Faint voices from Greenwich Village: Jung's impact on the first American avant-garde.

    Science.gov (United States)

    Sherry, Jay

    2011-11-01

    In 1913 Jung made a trip to New York which was to have an important impact on the creation of modern American culture. At the invitation of Beatrice Hinkle, the first Jungian analyst in the country, he spoke to the Liberal Club, a forum for discussing progressive topics. Jung was the leading spokesman for psychoanalysis and his ideas about creative fantasy resonated with popular interest in the ideas of William James and Henri Bergson. This paper will document that visit and the influence that Hinkle had on the young people who had gravitated to Greenwich Village. She promoted Jungian psychology through her analytical practice and her translation of Jung's Wandlungen und Symbole der Libido as Psychology of the Unconscious. Her influence is evident in four key neighbourhood institutions: The Masses, a socialist magazine, The Seven Arts, an avant-garde literary magazine, the Provincetown Players theatre ensemble, and the Heterodoxy Club, America's first feminist group. Her influence is also evident at The New School where several pioneering anthropologists employed the theory of psychological types as a tool for understanding social behaviour. This paper will demonstrate that a cultural moment usually seen through a Freudian lens had, in fact, a remarkably Jungian character. © 2011, The Society of Analytical Psychology.

  12. Safe childbirth: Concept Analysis According to the Walker and Avant Method

    Directory of Open Access Journals (Sweden)

    Fernanda Maria Carvalho Fontenele

    2017-06-01

    Full Text Available Objective: This study analyzed the concept of "Safe delivery" using the method proposed by Walker and Avant, which establishes eight steps for the construction of a concept. Method: Literature search was carried out in the Virtual Health Library (VHL and the Scientific Electronic Library Online (Scielo in the period from April to July 2016. Controlled descriptors were: "Parturition", "Safety" and "Patient safety", in Portuguese and English.  The compound term "Safe Delivery" was also used.  Thirty two productions were included in this analysis. Results: Among the attributes, maternal and fetal monitoring stand out and, as antecedent, the identification of risks for preventing damage. The reduction of maternal and infant mortality and the well-being of the mother-child binomial were evident in this work. Following the establishment of model case and opposite case, the definition of safe delivery was obtained: "the set of care measures that seek to identify risks, prevent damage and/or complications during delivery, ensuring maternal and fetal monitoring in favor of the welfare of mother and child ". Conclusion: The analysis of the essential attributes, its antecedents and consequences made it possible to define the concept of safe delivery. However, it is considered that this concept is changeable bearing in mind that there is a lack of randomized studies to identify potential risks to childbirth.

  13. Accident vasculaire cérébral hémorragique du tronc cérébral suite à une éclampsie du post partum: à propos d’un cas et revue de la littérature

    National Research Council Canada - National Science Library

    Ennaqui Khadija; Makayssi Assia; Boufettal Houssine; Samouh Naima

    2017-01-01

    Les accidents vasculaires cérébraux sont des accidents rares mais graves durant la grossesse et le post-partum, ils sont responsable d'une mortalité et d'une morbidité élevée, la pré éclampsie...

  14. Cerebral palsy.

    Science.gov (United States)

    Kent, Ruth M

    2013-01-01

    Cerebral palsy affects movement and posture causing activity limitation; it is a lifelong condition, with foreseeable complications. There are evidence-based interventions that will prevent participation restriction. Childhood interventions are generally delivered within multidisciplinary rehabilitation programs. Sadly young adults are often not transferred to an appropriate multidisciplinary adult neurodisability service. An unexplained neurological deterioration should warrant further investigation. Pain is an important underreported symptom and musculoskeletal complaints are prevalent. Disabled adults have less participation socially, in employment, marriage, and independent living related to health problems, discrimination, or lack of access to information, support, and equipment. Evidence-based interventions include a variety of modalities at all International Classification of Functioning, Disability, and Health levels to include support and adaptations. Rehabilitation interventions that have been shown to be effective include surgery in childhood, ankle-foot orthoses, strength training, and electrical stimulation. Management of spasticity is beneficial and has an evidence base. Orthotics and casting are also used. Systematic reviews of upper limb therapies also show the benefit of physical therapy exercise, strengthening, fitness training, and constraint therapy. Occupational therapy has a weaker evidence base than in other disabling conditions but many modalities are transferable. Speech therapy is effective although no specific intervention is better. Psychological wellbeing interventions, including improving self-efficacy, health knowledge, and coping skills, are beneficial. Management of continence, nutrition, and fatigue promote wellbeing. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. COMA - American avant rock : A study of the music of avant rock bands Thinking Plague, Motor Totemist Guild, U Totem and 5UU's and their relationship with 1970's progressive rock

    OpenAIRE

    Storløkken, Jarle Glesåen

    2008-01-01

    This study is dedicated to four bands that relate to the style of avant rock, as well as the organization in which they all (to a greater or lesser degree) took part in the mid-80s to the early 90s – the California Outside Music Association (COMA). The styles of these four groups – Thinking Plague, Motor Totemist Guild, U Totem and 5UU’s – are examined through analysis of musical scores and transcriptions, and also considered in the context of the COMA organization and its structure. In ...

  16. Distilled Avant-Garde Echoes: Word and Image in Architectural Periodicals of the 1920s and 1930s

    Directory of Open Access Journals (Sweden)

    Hélène Jannière

    2016-12-01

    Full Text Available Since the 1980s, architectural avant-garde publications, seen as a laboratory for artists and architects, have given rise to numerous research projects. Although recent scholarship tends toward a more balanced interpretation of architectural publications of the interwar period than studies from the 1980s, most research on architectural books and journals continues to point out only the parallels, or even just the ‘alliances’, between the innovative visual form – typography and photography – of those books and magazines and the ‘new architecture’ they intended to promote: relationships between form and contents. This article tackles the issue of this historical and aesthetical convergence. It draws on a new generation of studies that takes into account photography, graphic design and texts, simultaneously, and focuses on their association in the space of the book. By examining several case studies, it brings to light relationships of texts and images di erent from those dramatic and disruptive ones elaborated by the avant-garde. This is done, rst, by considering a wider range of professional periodicals of the late 1920s and 1930s – both avant-garde and traditional – and second, by focusing more on the modes of perception photography introduced within the space of the book than on photographic or typographic experiments. The driving hypothesis is that in periodicals of the late 1920s and 1930s, even in those of a rather traditional form ('L’Architecte, L’Architecture vivante, Quadrante', new modes of perceiving the space of the book as a whole gave rise to semantic associations generated by juxtapositions or e ects of distance between word and image. This article also puts into question the way two periodicals in particular, 'L’Architecture d’aujourd’hui' and 'Casabella', both deemed ‘modernist’, integrated some of the lessons of contemporary typography and photography.

  17. Cerebral Palsy (For Kids)

    Science.gov (United States)

    ... Dieting OK for Kids? Your Teeth Heart Murmurs Cerebral Palsy KidsHealth > For Kids > Cerebral Palsy Print A A A What's in this article? ... the first word you spoke? For kids with cerebral palsy, called CP for short, taking a first step ...

  18. Cerebral microangiopathies; Zerebrale Mikroangiopathien

    Energy Technology Data Exchange (ETDEWEB)

    Linn, Jennifer [Klinikum der Universitaet Muenchen (Germany). Abt. fuer Neuroradiologie

    2011-03-15

    Cerebral microangiopathies are a very heterogenous group of diseases characterized by pathological changes of the small cerebral vessels. They account for 20 - 30 % of all ischemic strokes. Degenerative microangiopathy and sporadic cerebral amyloid angiography represent the typical acquired cerebral microangiopathies, which are found in over 90 % of cases. Besides, a wide variety of rare, hereditary microangiopathy exists, as e.g. CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy), Fabrys disease and MELAS syndrome (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes). (orig.)

  19. The Magazine is the Message: het papieren netwerk\tvan de Europese neo-avant-garde (1958-1963

    Directory of Open Access Journals (Sweden)

    Johan Pas

    2014-07-01

    Full Text Available At this moment, postmodernism has become history. This allows a fresh look at the ‘pre-postmodern’ past. Rereading Zero and other radical artists’ magazines of the early 1960s gives us the opportunity to broaden the historical scope of the magazine as an artistic medium. Having been written almost exclusively from the conceptualist perspective of the late 1960s, the history of the artists’ publication (both magazine and book can benefit from an archaeology of the years before conceptual art. Especially at the time young DIY-oriented artists are rediscovering the potential of print, a more nuanced approach of the publications that are at the root of this practice, is of crucial importance. In this essay I will sketch a chronological topography of the crucial years between 1958 and 1963 and the use avant-garde artists made of the magazine medium. A detailed description of the neo-avant-garde artists’ magazines of this period provides the possibility to draw the network of the international Zeromovement and to situate it in a broader context.

  20. Implication des vésicules extracellulaires des cellules initiatrices tumorales dans l’augmentation de la perméabilité vasculaire du glioblastome

    OpenAIRE

    Treps, Lucas

    2015-01-01

    Brain microvessels are characterized by specific structure and organization within the neurovascular unit. Through highly selective endothelial junctions, the blood-brain barrier (BBB) controls exchanges of cells, fluids, plasmatic proteins and metabolites between blood and the cerebral compartment. VE-cadherin, a transmembrane protein of endothelial junctions, is of most importance in the vascular integrity. Indeed, its destabilization leads to BBB weakening and also breaking in some patholo...

  1. Brazilian contemporary literature and the dialogue with the historical avant-gardes: the surrealist experimentation in “Gordas levitando”, by Joca Reiners Terron

    Directory of Open Access Journals (Sweden)

    LUCAS TOLEDO DE ANDRADE

    2015-08-01

    Full Text Available This paper addresses both the dialogue between Brazilian contemporary literature and the historical avant-garde, that is to say the surrealism, by analyzing the short story “Gordas levitando, by Joca Reiners Terron. The theoretical framework for this analysis includes texts by Walter Benjamin, Peter Bürger, Maurice Nadeau, among others.

  2. Survival of images from avant-garde cinema Sobrevivência de imagens do cinema das vanguardas

    Directory of Open Access Journals (Sweden)

    Eduardo Peñuela Cañizal

    2008-11-01

    Full Text Available My intention here is to discuss the hypothesis that the technology of some media builds supports that ensure the survival of cinematographic images. My own interest in this theme lies in its potential for creating subtle forms of intertextuality. To this end, I deal with iconographic forms molded by avant-garde cinema, distinguishing between "relative" and "surrealistic" images. Minha intenção neste trabalho é lidar com o pressuposto de que a tecnologia de algumas media constrói suportes que garantem a sobrevivência das imagens, além de produzir modos sutis de intertextualidade. Para tanto, lido com a distinção de dois tipos de imagens: as que advêm da "relatividade" e as que se engendram no Surrealismo.

  3. Placing Bookmarks: The Institutionalisation and De-Institutionalisation of Hungarian Neo-Avant-Garde and Contemporary Art

    Directory of Open Access Journals (Sweden)

    Maja Fowkes

    2016-12-01

    Full Text Available The recent interest in avant-garde art from Hungary shown by international museums such as Tate has been paralleled by transformations to the country’s art institutions as a consequence of sweeping political changes. This essay contextualises these changes in relation to the expanding global market for art from the region, and examines the impact that initiatives by private galleries as well as artists and curators are having on the writing of a critical history of Hungarian art. An earlier version of this text was presented as a paper at the panel on ‘Collecting, Curating, Canonizing, Critiquing: The Institutionalization of Eastern European Art’ at the College Art Association conference, Washington D.C., February 2016.

  4. Transversalities Painting-Cinema: the concept of ‘the pictorial’ in the cinema of the first avant-gardes

    Directory of Open Access Journals (Sweden)

    Ricardo González García

    2017-05-01

    Full Text Available The aim of this article is to verify the intense relationship that has been maintained between the cinematographic medium and the artistic Avant-gardes, especially with painting. In order to do so, we analyse how the latter –after its historical interest in representing the movement– looks at the cinema, being influenced by it, which we can demonstrate through the examples that will follow. But the most interesting thing is perhaps to show how, after the mentioned relation, a certain experimental cinema ends up welcoming the concept of “the pictorial” for its discursive purposes, as well as for its processes of realization. Experiences that, from the dialogues around the light that both media share, lead us to the debate on their locations relative to the time; as synchronous communication means or diachronic transmission means.

  5. Bacteraemia in cerebral malaria

    NARCIS (Netherlands)

    Enwere, G.; van Hensbroek, M. B.; Adegbola, R.; Palmer, A.; Onyiora, E.; Weber, M.; Greenwood, B.

    1998-01-01

    As part of a treatment trial of cerebral malaria, blood cultures were done in 276 Gambian children, aged between 1 and 9 years, with cerebral malaria. Fourteen (5%) of these were positive. The organisms isolated were Staphylococcus aureus (6), coliforms (4), Pseudomonas spp. (2), Salmonella spp. (1)

  6. Cerebral Palsy (CP) Quiz

    Science.gov (United States)

    ... What's this? Submit Button Past Emails Pop Quiz: Cerebral Palsy Language: English (US) Español (Spanish) Recommend on Facebook ... Sandy is the parent of a child with cerebral palsy and the Board President of Gio’s Garden , a ...

  7. Cerebral tomo-scintigraphies before and after PL in HPN: results after 3 years; Tomoscintigraphies cerebrales avant et apres PL dans les HPN: bilan sur 3 ans

    Energy Technology Data Exchange (ETDEWEB)

    Chevalier, J.; Coubes, Ph.; Seignarbieux, F.; Carlander, B.; Camu, W.; Zanca, M.; Rossi, M. [CHU GUI DE CHAULIAC 34295 MONTPELLIER (France)

    1997-12-31

    One hundred and sixty one patients carrying a symptomatology suggesting a HPN, were subject to a neuro-physiologic and emission tomography examination before and after depletive PL. The SPECTs were performed after injection with {sup 99m}Tc-HMPAO or ECD (the same tracer for the two controls), by means of a single circular head Sophy Camera at the beginning, then since December 1995, with a 3 head PRISM 3000 Picker camera. A semi-quantitative analysis has completed the qualitative aspect of perfusion, each patient being its own control case. Certain patients could not be included in the study due to lack of clinical continuation or HPN diagnosis. Ninety nine have been retained (64 M, 35 F), of 68.8 years average age (25 - 92). Fifty three presented an amelioration of perfusion after depletive PL manifested qualitatively by an thickening of the cortical ring and an increase of 10% in the fixation index, as semi-quantitative analysis. Forty six presented a stability or an aggravation manifested by a thinning of the cortical ring and an extension of rupture zones, associated with a decrease in the fixation index. In most of negative cases we found images suggesting degenerative dementia syndromes, two times a Pick`s disease (afterwards confirmed) and three times a vascular pathology while, when there was no other associated pathology, the anomalies were moderated and the HPN signs discrete. Consequently, this test is especially interesting when it is positive permitting a good prognostic for the derivation surgery intervention. When it is negative the prognostic is more questionable and the associated pathologies are to be considered

  8. Unilateral cerebral polymicrogyria with ipsilateral cerebral hemiatrophy

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, Katsumi [Department of Radiology, Kyoto City Hospital, 1-2 Higashi-Takada-cho, Mibu, Nakagyo-ku, 604-8845 Kyoto (Japan); Kanda, Toyoko; Yamori, Yuriko [Department of Pediatric Neurology, St. Joseph Hospital for Handicapped Children, 603-8323 Kyoto (Japan)

    2002-10-01

    We evaluated six children in whom MR imaging showed unilateral cerebral polymicrogyria associated with ipsilateral cerebral atrophy and ipsilateral brain stem atrophy. The aim of this study was to clarify whether this disorder based on neuroimaging constitutes a new homogeneous clinical entity. The subjects were six children whose ages at the time of MR imaging ranged from 8 months to 11 years. Their clinical and MR features were analyzed. All of the children were born between 38 and 42 weeks gestation, without any significant perinatal events. Spastic hemiplegia and epilepsy were observed in all of the patients, and mental retardation was observed in four. The MR findings included unilateral cerebral polymicrogyria associated with ipsilateral cerebral hemiatrophy and ipsilateral brain stem atrophy in all patients. The ipsilateral sylvian fissure was hypoplastic in four patients. These patients showed relatively homogeneous clinical and neuroimaging features. Although the additional clinical features varied according to the site and the extent affected by the polymicrogyria, this disorder could constitute a new relatively homogeneous clinical entity. (orig.)

  9. Trends in cerebral palsy.

    Science.gov (United States)

    Blair, E

    2001-05-01

    The terms trend and cerebral palsy are defined emphazing the non-diagnostic nature of the cerebral palsy label. Criteria necessary for valid estimation of trends include constant methods of estimating population based numerators and denominators over a number of years, which render them hard to obtain, particularly in developing countries. Trends in cerebral palsy are an important source of aetiological hypotheses for congenital cerebral palsy, provide corroborative evidence for existing hypotheses and may direct strategies to prevent post neonatally acquired cerebral palsy. In developed countries the overall frequency of congenital cerebral palsy has changed little during the last decades. However this masks a dramatic increase in the frequency in the infants born most preterm, a decline in those born moderately preterm and little change in those born at term, but the severity of impairments of those born very preterm is decreasing while for those born at term severity in increasing. These changes may be the result of the increasing ability of perinatal care to rescue very vulnerable infants. There is less agreement in trends of post neonatally acquired cerebral palsy which are more sensitive to social well being.

  10. Acquired cerebral dyschromatopsia.

    Science.gov (United States)

    Green, G J; Lessell, S

    1977-01-01

    Color blindness developed in five patients apparently because of lesions in the posterior portions of both cerebral hemispheres. Three of them also had symptoms of prosopagnosia. The lesions were neoplastic in two and vascular in three of the patients. It would appear that bilateral, inferior, occipital lobe lesions may be responsible both for acquired cerebral dyschromatopsia and prosopagnosia. Evidence from experimental investigations in primates suggests that the areas of the cerebral hemispheres analogous to those involved in these patients, may be specialized for the processing of colored stimuli.

  11. "El cuento ficticio": la especularidad como expresión de la vanguardia hispanoamericana "The fictitious short story": metafiction as an expression of Spanish American Avant-Garde

    Directory of Open Access Journals (Sweden)

    Margarita Figueroa

    2008-12-01

    Full Text Available El objetivo de este estudio es examinar el funcionamiento de la especularidad o metaficción en la cual se concentra "El cuento ficticio" (1927 de Julio Garmendia para determinar que su especularidad es una expresión de la vanguardia hispanoamericana de las décadas del veinte y treinta o primera vanguardia. Primeramente, se estudia el texto de Garmendia como modelo de especularidad vanguardista por cuanto responde a la ruptura con la tradición realista y al experimentalismo. Experimentalismo de la estructura especular de "El cuento ficticio" porque se vale de un discurso expositivo en tiempo presente y futuro que sustituye el discurso narrativo en tiempo pasado como forma verbal característica de la narración (Weinrich. En la última parte, el texto de Garmendia se relaciona con novelas hispanoamericanas de la primera vanguardia que presentan la misma estructura especular. El texto de Garmendia es el primer relato especular hispanoamericano que responde a las innovaciones vanguardistas derivadas de la especularidad presente en novelas hispanoamericanas vanguardistas.The objective of this study is to analyze how metafiction, on which Julio Garmendia’s "El cuento ficticio" (1927 is concentrated, works in order to determine that its metafiction is an expression of the Spanish American Avant-Garde of the twenties and thirties, or first Avant-Garde. Firstly, Garmendia’s text is studied as a model of avant-garde metafiction because it responds to the breaking with the realist tradition and to experimentalism. Experimentalism of the metafictional structure of "El cuento ficticio" because it uses an expositive discourse in the present and future tenses that replaces the narrative discourse in the past tense as a verbal form which characterizes narration (Weinrich. In the last part, Garmendia’s text is related to the Spanish American first avant-garde novels that have the same metafictional structure. Garmendia’s text is the first Spanish

  12. La préservation du capital vasculaire au CHU Ibn Sina de Rabat-Maroc: rôle de l’infirmier

    Science.gov (United States)

    Bouattar, Tarik; Bezzaz, Aicha; Abdellaoui, Khalil; Lamchahab, Fatima Ezzahra; Benamar, Loubna; Ezaitouni, Fatima; Hassam, Badredine; Bayahia, Rabia; Ouzeddoun, Naima

    2012-01-01

    Introduction Tout patient ayant une maladie chronique nécessitant des prélèvements sanguins répétés ou des traitements par voie veineuse ou susceptible d’évoluer vers l’insuffisance rénale chronique, doit bénéficier d’une stratégie de préservation de son réseau veineux. Le but de ce travail etait de déterminer le rôle de l’infirmier dans la protection du réseau veineux superficiel. Méthodes Etude transversale réalisée au mois d’Avril 2010 à l’hôpital Ibn Sina de Rabat ayant intéressée les infirmiers exerçant dans différents services prenant en charge des patients ayant des pathologies rénales chroniques ou une maladie générale susceptible de se compliquer d’atteinte rénale. Résultats Parmi les 80 infirmiers sollicités, 66 ont complété le questionnaire avec un âge moyen de 42,7 ±11ans et un sex-ratio à 0,7. L’ancienneté moyenne en soins était de 227,7 ± 116,7 mois. 37 % des infirmiers n’étaient pas informés sur la préservation du capital veineux. Le membre supérieur droit était ponctionné dans 92,3% des cas. Le site de ponction le plus utilisé était le dos de la main dans 84,6 % des cas. La dilatation des veines par le réchauffement était notée dans 63,3% des cas, par passage d’alcool dans 54,5% des cas et l’emploi du garrot était retrouvé dans 95,5% des cas. Les venojects étaient de 18 gauge dans 18,2 % des cas et de 21 gauge dans 81,8% des cas. Les intranules étaient de 18 gauge dans 78,8% des cas et de 20 gauge dans 21,2 % des cas. Durant les six derniers mois avant l’étude, les complications au niveau du site de ponction étaient notées dans 41 % des cas. Conclusion L’information et l’éducation du personnel paramédical sont obligatoires ainsi que l’utilisation des cathéters veineux de petit calibre afin d’assurer cette protection. PMID:22593793

  13. Five-year outcome of a stroke cohort in Martinique, French West Indies: Etude Réalisée en Martinique et Centrée sur l'Incidence des Accidents vasculaires cérebraux, Part 2.

    Science.gov (United States)

    Chausson, Nicolas; Olindo, Stéphane; Cabre, Philippe; Saint-Vil, Martine; Smadja, Didier

    2010-04-01

    Limited information exists on stroke among black populations outside the United States and United Kingdom. Part 1 of the Etude Réalisée en Martinique et Centrée sur l'Incidence des Accidents vasculaires cérebraux (ERMANCIA) provided strong epidemiologic data on the incidence of first-ever stroke in a black Caribbean population and showed a 40% greater incidence of stroke in Martinique than in continental France. In ERMANCIA part 2, we evaluated the long-term outcomes of our cohort. Survivors of a first stroke from this prospective, community-based, stroke incidence study were reassessed at 5 years according to standardized procedures and criteria, including the modified Rankin scale, Barthel Index, Montgomery-Asberg Depression-Rating Scale, Mini-Mental State Examination, treatment compliance, and blood pressure control. Of the 293 survivors of the original 580 (50.5%) patients who were still alive 5 years after stroke, 262 (89.4%) were assessed. Among these survivors, 66.4% were functionally independent and 43% were completely autonomous for activities of daily living, but 25.8% were depressed and 58.9% were cognitively impaired. Only 50 of 170 (29.4%) of the hypertensive patients achieved their target blood pressure. These results highlight the very poor blood pressure control and the very high rate of cognitive impairment in Martinican patients after stroke. As a consequence, a poststroke prevention network was established in Martinique.

  14. Neonatal Cerebral Sinovenous Thrombosis

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2006-04-01

    Full Text Available The presentation, treatment, and outcome of neonatal cerebral sinovenous thrombosis (SVT were studied in 42 children, using neurology clinic records (1986-2005 at Indiana University School of Medicine.

  15. Cerebral Manifestations of Preeclampsia

    NARCIS (Netherlands)

    I.A. Brussé (Ingrid)

    2016-01-01

    textabstractThis thesis intends to describe and explain the course of clinical neurophysiological and neuropsychological parameters in patients with hypertensive disorders in pregnancy. We aimed to improve knowledge on cerebral pathophysiological mechanisms of preeclampsia related to signs and

  16. Cerebral Cavernous Malformation

    Science.gov (United States)

    ... Division of Neuroscience Director, NIH BRAIN Initiative® Health Scientist Administrator Channels Synapses Circuits Cluster Scientific Director, Division of Intramural Research Featured Director's Message menu search Enter Search Term Submit Search Cerebral Cavernous Malformation ...

  17. Dysphagia in cerebral palsy

    National Research Council Canada - National Science Library

    Annamaria Salghetti; Andrea Martinuzzi

    2012-01-01

      Feeding problems are often present in children with neuromotor impairment: dysphagia is usually seen in the most severe form of cerebral palsy and it's defined as the difficulty with any of the four phases of swallowing...

  18. Cerebral Palsy in Cinema

    Directory of Open Access Journals (Sweden)

    María Lucila Merino Marcos

    2008-10-01

    Full Text Available In the last twenty-five years, a number of important films have been made in which the protagonist or supporting actor has had, or simulated having, cerebral palsy.  On occasion, these characters have been played by people with disabilities.  In the course of this field’s history, films have portrayed many diverse aspects of cerebral palsy such as healthcare and social and familial obligations.

  19. Cerebral venous angiomas

    Energy Technology Data Exchange (ETDEWEB)

    Agnoli, A.L.; Hildebrandt, G.

    1985-01-01

    Clinical symptoms and radiological signs in 15 patients with cerebral venous malformations are presented and the diagnostic problems discussed. The circulation time in combination with cerebral malformations and angiomas of the scalp are described. CT findings in cases of venous malformations of the brain stem are evaluated. Spot-like enhancement, as well as sharply demarcated round shaped enhancement are characteristic for venous angiomas. Cavernous angiomas usually present as homogenous or inhomogenous round shaped enhanced areas. (Author).

  20. Acute ischemic cerebral attack

    OpenAIRE

    Franco-Garcia Samir; Barreiro-Pinto Belis

    2010-01-01

    The decrease of the cerebral blood flow below the threshold of autoregulation led to changes of cerebral ischemia and necrosis that traduce in signs and symtoms of focal neurologic dysfunction called acute cerebrovascular symdrome (ACS) or stroke. Two big groups according to its etiology are included in this category the hemorragic that constitue a 20% and the ischemic a 80% of cases. Great interest has wom the ischemic ACS because of its high social burden, being the third cause of no violen...

  1. Eklektizismus im Avant-propos: Balzacs Erklärung der Erkenntnisform und der Paradigmenwechsel in ‚Geschichtsschreibung‘ und Vorworttradition

    Directory of Open Access Journals (Sweden)

    Cordula Reichart

    2016-01-01

    Full Text Available Der vorliegende Beitrag zu Honoré de Balzacs Avant-propos macht es sich zum Ziel, exemplarische Parameter des Avant-propos zur Comédie humaine (die Vorstellung des Gesamtplans, der Werkidee, die Relaisfunktion zum Werk bzw. zur Kritik in einen funktionalen Zusammenhang zu bringen mit der Erklärung jener Aspekte des Gesamtanliegens, die die Kritik besonders herausforderten, weil sie dem Leser (noch verborgen bzw. grundsätzlich entzogen bleiben müssen. Der Eklektizismus der Balzac’schen Vorrede ist dabei mehr als nur ein Stilphänomen. Er dient der Erklärung der Erkenntnisform und man darf sich fragen, inwiefern dies nicht systematische Konsequenzen hat für die poetischen Verfahren und maßgeblichen Anteil an der Prägung eines neuen, modernen Vorwortkonzepts.

  2. Cerebral palsy and congenital malformations

    DEFF Research Database (Denmark)

    Garne, Ester; Dolk, Helen; Krägeloh-Mann, Inge

    2007-01-01

    AIM: To determine the proportion of children with cerebral palsy (CP) who have cerebral and non-cerebral congenital malformations. METHODS: Data from 11 CP registries contributing to the European Cerebral Palsy Database (SCPE), for children born in the period 1976-1996. The malformations were...... classified as recognized syndromes, chromosomal anomalies, cerebral malformations or non-cerebral malformations. Prevalence of malformations was compared to published data on livebirths from a European database of congenital malformations (EUROCAT). RESULTS: Overall 547 out of 4584 children (11.9%) with CP...... were reported to have a congenital malformation. The majority (8.6% of all children) were diagnosed with a cerebral malformation. The most frequent types of cerebral malformations were microcephaly and hydrocephaly. Non-cerebral malformations were present in 97 CP children and in further 14 CP children...

  3. ‘We the Avant-Garde’. A History from Below of Dutch Heroin Use in the 1970s

    Directory of Open Access Journals (Sweden)

    Gemma Blok

    2017-03-01

    Full Text Available In the 1970s the Netherlands (like many other western countries was shocked by a sudden wave of heroin use. The heroin ‘epidemic’ is  currently framed as a public health problem that has been solved in a commendably humane fashion. In the mean time heroin users have gained a ‘loser image’. Using memoirs written by and interviews with former heroin users, this article argues that heroin use was initially linked to cultural rebellion, self-development and social criticism. We need to take this forgotten aspect of the history of the Dutch heroin ‘epidemic’ into account when we try to explain this historical phenomenon. ‘Wij de avant-garde’. Een history from below van heroïnegebruik in Nederland in de jaren zeventigIn de jaren zeventig van de vorige eeuw werd Nederland (net als veel andere westerse landen opgeschrikt door een plotselinge golf van heroïnegebruik. Deze ‘heroïne-epidemie’ wordt momenteel beschouwd als volksgezondheidsprobleem dat succesvol is bedwongen, op een bewonderenswaardig humane wijze. Ondertussen hebben heroïnegebruikers een ‘loser’ imago gekregen. Op basis van memoires geschreven door en interviews met voormalige heroïnegebruikers, betoogt dit artikel dat het gebruik van heroïne oorspronkelijk verbonden was met culturele rebellie, zelfontplooiing en cultuurkritiek. Dit vergeten aspect van de ‘epidemie’ is onderdeel van de verklaring voor de populariteit van opiaten destijds.

  4. The British Avant Garde: A Joint Venture Between the New York Cultural Center and Studio International Magazine

    Directory of Open Access Journals (Sweden)

    Jo Melvin

    2016-07-01

    Full Text Available This essay considers the relevance of The British Avant Garde exhibition at the New York Cultural Center in 1971 to the reputation and discussion of British artists in the US, and its subsequent impact in Britain. It situates the exhibition with reference to Conceptual Art and Conceptual Aspects at the NYCC and Information at the Museum of Modern Art, both held in 1970, and within the background milieu of a lively transatlantic and multi-directional network of artists such as Terry Atkinson, Michael Baldwin, Ian Burn, Barry Flanagan, Dan Graham, Joseph Kosuth, Christine Kozlov, Richard Long, Mel Ramsden, Sol LeWitt and Lawrence Weiner, who were developing alternative ways to make and to distribute work by using text, photocopies, and self-publication as forms of production as well as becoming the site of exhibition. Devised by Charles Harrison, assistant editor of Studio International magazine, the exhibition was a collaboration between the magazine and the NYCC, directed by Donald Karshan. Despite the mixed press reviews in New York, the exhibition paved the way for establishing institutional support for the artists in the UK.

  5. “When I Grow Up, I Will be an Artist.” Japanese Avant-garde’s Experimental Sandpit

    Directory of Open Access Journals (Sweden)

    klara / HRVATIN

    2017-01-01

    Full Text Available Sōgetsu Art Center, one of the most important venues for the avant-garde in 1960s Japan, could be defined as an artistic “experimental sandpit”. Its activities brought new musical expressions to the world of Japanese art, and lead to the independent film production. Japanese artists could play in this sandpit with a group of interdisciplinary peers and thus search for their most suitable artistic styles. Good examples are film director Hiroshi Teshigahara (1927–2001, playwright Kōbō Abe (1924–1993 and musician Tōru Takemitsu (1930–1996. The article gives an insight into the artistic associations and events, which took place under the roof of the Sōgetsu Art Center in the period from September 1958 to March 1971. The emphasis will be put on the main associations; activities related to the fields of jazz music, contemporary music, experimental film and animation. We will look for the common ground among these, and note the innovations which were brought about by the main participants at the Center in the fields of music and film.

  6. « The Long Freak Out » : musique inachevée et folie contre-culturelle dans le rock d’avant-garde des années 1960 et 1970

    OpenAIRE

    Keister, Jay

    2015-01-01

    This article examines avant-garde ‘freak out’ recordings in rock music: extended album tracks that suggest madness in their sonic anarchy, conceptual absurdity and amateur technique. Products of the counterculture rooted in the historical avant-garde, these recordings by musicians in the 1960s and 1970s rejected musical conventions of song structure, meaning and competence in their attacks on an emerging music industry. While such extreme recordings bring to the fore the uneasy relationship b...

  7. “The Many Languages of the Avant-Garde”: In conversation with Grzegorz Bral of Teatr Pieśń Kozła (Song of the Goat Theatre

    Directory of Open Access Journals (Sweden)

    Sakowska Aleksandra

    2014-12-01

    Full Text Available How to theorise and review avant-garde Shakespeare? Which theoretical paradigms should be applied when Shakespearean productions are multicultural and yet come from a specific locale? These and other many questions interrogating the language of performance in global avant-garde Shakespeare productions are put forward to Grzegorz Bral, the director of the Song of the Goat ensemble in the context of their evolving performance of Macbeth (2006/2008 and their Songs of Lear (2012.

  8. Mutual exchange between Polish and Belgian magazines: a case study in cultural mobility within the interwar network of the avant-garde

    Directory of Open Access Journals (Sweden)

    Michał Wenderski

    2015-07-01

    Full Text Available In January 1924, Flemish avant-garde magazine Het Overzicht published a list of its congenial modernist for­ma­tions named ‘Het Netwerk’. It named nineteen magazines from Europe, the United States and Brazil, including the Polish magazine Zwrotnica. It exemplified the close and direct relationships within the supranational network of the avant-garde. Various formations belonging to this network, both bigger and smaller nodes, were linked to each other, often directly through befriended artists and writers. It did not only concern places such as Paris or Berlin, but also less pivotal nodes of the avant-garde network. In this paper I will present a case study of two countries, namely Poland and Belgium, as an example of European interwar cultural mobility. Joined in their pursuit of modern art, and crossing national and linguistic frontiers, Polish, French and Dutch-language magazines exchanged and re-printed each other’s texts and artworks, a practice also discussed in the correspondence between their representatives. Based on such tangible traces I will describe the cultural mobility and mutual exchange between the Polish and Belgian modernist journals, and attempt to shed light on the features, dynamics, and key figures of the network.

  9. Neurological Impact of World War I on the Artistic Avant-Garde: The Examples of André Breton, Guillaume Apollinaire and Blaise Cendrars.

    Science.gov (United States)

    Bogousslavsky, Julien; Tatu, Laurent

    2016-01-01

    World War I erupted at a time when artistic avant-gardes were particularly thriving across Europe. Young poets, writers, painters and sculptors were called to arms or voluntary enrolled to fight, and several of them died during the conflict. Among others, it dramatically changed their creative output, either through specific wounds or through personal encounters and experiences. These individual events then significantly modified the course of the literary and artistic avant-garde movements. Three particularly illustrative examples of avant-garde French poets are presented here: André Breton (1896-1966), Guillaume Apollinaire (1880-1918) and Blaise Cendrars (1887-1961). The deep source of the surrealist movement can indeed be found in André Breton's involvement as an auxiliary physician with critical interest in neuropsychiatry, which caused him to discover automatic writing. Guillaume Apollinaire's right temporal subdural hematoma strongly modified his emotional state and subsequent artistic activities. Alternatively, after losing his right, writing hand, Blaise Cendrars not only substituted it with a phantom but also rapidly switched from poetry to novels after he learnt to write with his left hand. © 2016 S. Karger AG, Basel.

  10. Monitoring of cerebral haemodynamics in newborn infants

    DEFF Research Database (Denmark)

    Liem, K Djien; Greisen, Gorm

    2010-01-01

    The most important cerebrovascular injuries in newborn infants, particularly in preterm infants, are cerebral haemorrhage and ischemic injury. The typical cerebral vascular anatomy and the disturbance of cerebral haemodynamics play important roles in the pathophysiology. The term 'cerebral...

  11. Duplicated middle cerebral artery

    Science.gov (United States)

    Perez, Jesus; Machado, Calixto; Scherle, Claudio; Hierro, Daniel

    2009-01-01

    Duplicated middle cerebral artery (DMCA) is an anomalous vessel arising from the internal carotid artery. The incidence DMCA is relatively law, and an association between this anomaly and cerebral aneurysms has been documented. There is a controversy whether DMCA may have perforating arteries. This is an important fact to consider in aneurysm surgery. We report the case of a 34-year-old black woman who suffered a subarachnoid hemorrhage and the angiography a left DMCA, and an aneurysm in an inferior branch of the main MCA. The DMCA and the MCA had perforating arteries. The aneurysm was clipped without complications. The observation of perforating arteries in our patient confirms that the DMCA may have perforating arteries. This is very important to be considered in cerebral aneurysms surgery. Moreover, the DMCA may potentially serve as a collateral blood supply to the MCA territory in cases of MCA occlusion. PMID:22140405

  12. L’évaluation du risque cardiaque avant l’utilisation de stimulants chez les enfants et les adolescents

    Science.gov (United States)

    Bélanger, SA; Warren, AE; Hamilton, RM; Gray, C; Gow, RM; Sanatani, S; Côté, J-M; Lougheed, J; LeBlanc, J; Martin, S; Miles, B; Mitchell, C; Gorman, DA; Weiss, M; Schachar, R

    2009-01-01

    Les décisions en matière de réglementation et les documents scientifiques au sujet de la prise en charge du trouble de déficit de l’attention avec hyperactivité (TDAH) soulèvent des questions quant à l’innocuité des médicaments et à l’évaluation convenable à effectuer avant le traitement afin de déterminer la pertinence d’une pharmacothérapie. Ce constat est particulièrement vrai en présence de cardiopathies structurelles ou fonctionnelles. Le présent article contient l’analyse des données disponibles, y compris les publications révisées par des pairs, des données tirées du site Web de la Food and Drug Administration des États-Unis au sujet des réactions indésirables déclarées chez des enfants qui prennent des stimulants, ainsi que des données de Santé Canada sur le même problème. Des lignes directrices consensuelles sur l’évaluation pertinente sont proposées d’après l’apport des membres de la Société canadienne de pédiatrie, de la Société canadienne de cardiologie et de l’Académie canadienne de psychiatrie de l’enfant et de l’adolescent, qui possèdent notamment des compétences et des connaissances précises tant dans le secteur du TDAH que de la cardiologie pédiatrique. Le présent document de principes prône une anamnèse et un examen physique détaillés avant la prescription de stimulants et s’attarde sur le dépistage des facteurs de risque de mort subite, mais il ne contient pas de recommandations systématiques de dépistage électrocardiographique ou de consultations avec un spécialiste en cardiologie, à moins que les antécédents ou que l’examen physique ne le justifient. Le document contient un questionnaire pour repérer les enfants potentiellement vulnérables à une mort subite (quel que soit le type de TDAH ou les médicaments utilisés pour le traiter). Même si les recommandations dépendent des meilleures données probantes disponibles, le comité s’entend pour affirmer que

  13. Cerebral palsy-management.

    Science.gov (United States)

    Singhi, Pratibha D

    2004-07-01

    Cerebral Palsy encompasses a heterogeneous group of non-progressive motor disorders caused by injury to the developing brain. Management is best done in a multidisciplinary set up under one roof. Comprehensive assessment of the child to evaluate functional ability and associated problems is followed by an individualized plan of management with long term goals and short term objectives. Participation of the family is pivotal to ensure proper habilitation of the child. A home-based management plan is advocated. Considerable experience, sensitivity and understanding are needed both for breaking the news and counselling the parents of a child with cerebral palsy.

  14. Is cerebral hemorrhage approaching?

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Hirokazu; Suzuki, Yukiko; Yoneyama, Takumi; Hamasuna, Ryouichi; Fujime, Kenichi; Goya, Tomokazu [Junwakai Memorial Hospital, Miyazaki (Japan)

    2001-09-01

    In Junwakai Memorial Hospital, from May, 2000 to April, 2001, 1042 patients underwent MRI examination to detect intracerebral microbleed (MB). This series included 481 hypertensive cases and 109 intra-cerebral and cerebellar hemorrhage patients. MB was identified by MRI GRASS image that detects hemosiderin with high sensitivity. The occurrence of MB is high in men and increased with the age. The hypertensive patients showed increased frequency of MB in proportion to the duration of hypertension. Almost all of the symptomatic cerebral and cerebellar hemorrhage cases showed multiple MBs except for massive hemorrhagic lesions. Therefore, MB can be an antecedant feature of the inpending symptomatic intracerebral and cerebellar hemorrhages. (author)

  15. [Multiple cerebral tuberculomas].

    Science.gov (United States)

    Noriega, L; Villarreal, F

    The tuberculosis is a disease that continues being important cause of morbidity and mortality at worldwide level. Its presentation as tuberculomas cerebral manifold at level of the central nervous system is little frequent in immunocompetent patients and can be confused with other etiology. An indigenous young man, immunocompetent consulted for history of headache, nausea, vomits, convulsions, double vision and hemiparesia left side, which in the cerebral tomography of revenue was showing injuries compatible with cerebral abscesses; for which he received treatment with antibiotics without improvement for what there takes biopsy of the injuries that reported tuberculomas, specific treatment being initiated later and the primary area being investigated without the same one be detecting. After the first procedural step with evident clinical and radiographic improvement. The tuberculosis in anyone of their forms of presentation must be included within the diagnosis differential of the patients in our endemic countries for this disease. The clinical and radiological diagnosis of cerebral injuries is difficult and single usually it obtains to the diagnosis during a pathology study that shows tuberculomas with caseosa necrosis, epiteliodes cell and the acid alcohol bacilli resistant.

  16. Cerebral Palsy Litigation

    Science.gov (United States)

    Sartwelle, Thomas P.

    2015-01-01

    The cardinal driver of cerebral palsy litigation is electronic fetal monitoring, which has continued unabated for 40 years. Electronic fetal monitoring, however, is based on 19th-century childbirth myths, a virtually nonexistent scientific foundation, and has a false positive rate exceeding 99%. It has not affected the incidence of cerebral palsy. Electronic fetal monitoring has, however, increased the cesarian section rate, with the expected increase in mortality and morbidity risks to mothers and babies alike. This article explains why electronic fetal monitoring remains endorsed as efficacious in the worlds’ labor rooms and courtrooms despite being such a feeble medical modality. It also reviews the reasons professional organizations have failed to condemn the use of electronic fetal monitoring in courtrooms. The failures of tort reform, special cerebral palsy courts, and damage limits to stem the escalating litigation are discussed. Finally, the authors propose using a currently available evidence rule—the Daubert doctrine that excludes “junk science” from the courtroom—as the beginning of the end to cerebral palsy litigation and electronic fetal monitoring’s 40-year masquerade as science. PMID:25183322

  17. CASE REPORT Cerebral schistosomiasis

    African Journals Online (AJOL)

    0b013e3182704d1e]. 5. Sanelli PC, Lev MH, Gonzalez RG, Schaefer PW. Unique linear and nodular MR enhancement pattern in schistosomiasis of the central nervous system: Report of three patients. AJR 2001;177(6):1471-1474. Cerebral schistosomiasis.

  18. Parálisis cerebral Cerebral palsy

    OpenAIRE

    Jorge Malagon Valdez

    2007-01-01

    El término parálisis cerebral (PC) engloba a un gran número de síndromes neurológicos clínicos, de etiología diversa. Estos síndromes se caracterizan por tener una sintomatología común: los trastornos motores. Algunos autores prefieren manejar términos como "encefalopatía fija", "encefalopatías no evolutivas". Se mencionan la utilidad de programas de intervención temprana y métodos especiales de rehabilitación, así como el manejo de las deficiencias asociadas como la epilepsia, deficiencia me...

  19. Parálisis cerebral Cerebral palsy

    Directory of Open Access Journals (Sweden)

    Jorge Malagon Valdez

    2007-01-01

    Full Text Available El término parálisis cerebral (PC engloba a un gran número de síndromes neurológicos clínicos, de etiología diversa. Estos síndromes se caracterizan por tener una sintomatología común: los trastornos motores. Algunos autores prefieren manejar términos como "encefalopatía fija", "encefalopatías no evolutivas". Se mencionan la utilidad de programas de intervención temprana y métodos especiales de rehabilitación, así como el manejo de las deficiencias asociadas como la epilepsia, deficiencia mental, trastornos del lenguaje, audición, visión, déficit de la atención que mejoran el pronóstico de manera significativa. El pronóstico también depende de la gravedad del padecimiento y de las manifestaciones asociadas.The term cerebral palsy (CP, is used for a great number of clinical neurological syndromes. The syndromes are characterized by having a common cause, motor defects. It is important, because they can cause a brain damage by presenting motor defects and some associated deficiencies, such as mental deficiency, epilepsy, language and visual defects and pseudobulbar paralysis, with the nonevolving fact. Some authors prefer using terms such as "non-evolving encephalopathies". In the treatment the utility of prevention programs of early stimulation and special rehabilitation methods, and treatment of associated deficiencies such as epilepsy, mental deficiency, language, audition and visual problems, and the attention deficit improve the prognosis in an important way. The prognosis depends on the severity of the disease and the associated manifestations.

  20. Qualité de vie et vécu de la maladie, avant et après hystérectomie ...

    African Journals Online (AJOL)

    En Post-opératoire, ont été noté les dyspareunies transitoires30/40 (75%) ; les céphalées secondaires à l'anesthésie 4/40 (10%). Le vécu psychologique a été dominé avant l'HV par la peur de la chirurgie chez toutes les patientes, les troubles du sommeil 38/40 (95%), l'angoisse 30 /40(75%) , un sentiment de honte lié aux ...

  1. Phonemes, Graphemes, Dabs of Paint: Roman Jakobson, the Russian avant-garde and the search for the shared basic elements of painting and poetry

    OpenAIRE

    Hofstede, Bregje

    2012-01-01

    The subject of this paper is the supposed affinity between painting and poetry as theorised by the linguist Roman Jakobson who played a crucial role for the Russian avant-garde and its close association of painting and poetry. The paper focuses on Jakobson's relation to the two 1913 manifestos "The Word as Such" and "The Letter as Such", written by the poets Chlebnikov and Kruchenyck, and on Jakobson's own (lost) reply. It calls into question the accuracy of Jakobson's claim of having influce...

  2. Avant-propos

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    Mikołaj Nkollo

    2012-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XXXIX/3 Studia Romanica Posnaniensia jest efektem.

  3. Avant-propos

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    Teresa Tomaszkiewicz

    2012-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XXXIX/2 Studia Romanica Posnaniensia jest efektem.

  4. Avant-propos

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    Jerzy Lis

    2013-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XL/4 Studia Romanica Posnaniensia jest efektem.

  5. Avant-propos

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    Katarzyna Karpińska-Szaj

    2011-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XXXVIII/2 Studia Romanica Posnaniensia jest efektem.

  6. Avant-propos

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    Agnieszka Kornelia Kaliska

    2012-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XXXIX/4 Studia Romanica Posnaniensia jest efektem.

  7. Avant-propos

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    Joanna Teklik

    2012-01-01

    Full Text Available Słowo wstępne redaktora naukowego, przedstawiające tematykę tomu, krótko omawiające zebrane artykuły oraz opowiadające o pracach naukowych, których numer XXXIX/1 Studia Romanica Posnaniensia jest efektem.

  8. Avant-propos

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    Raymond Jamous

    2011-06-01

    Full Text Available Identités, nations, globalisation : ces trois termes concentrent un grand nombre d’interrogations sur les transformations que vit le monde actuel. Ce sont eux qui ont fourni matière à réflexion à la première manifestation internationale coorganisée par le Laboratoire d’ethnologie et de sociologie comparative (cnrs et université Paris X, Nanterre et le Centro de Investigaciones y Estudios Superiores en Antropología Social (ciesas, Mexico. Du 6 au 9 novembre 2000, un colloque franco-mexicain ...

  9. Avant-propos

    OpenAIRE

    Pinto, Louis

    2017-01-01

    La catégorie de « féminin » a été au cœur de plusieurs recherches qui concernent l’ordre mythico-rituel, religieux, magique (Jean-Pierre Albert, Giordana Charuti, Jacques Maître, Catherine Weinberger-Thomas) et, aussi, idéologique, politique (Francine Muel-Dreyfus). Ce n’est pas un hasard puisqu’il s’agit de domaines qui sont prédisposés à refléter les oppositions entre sexes, ou, plus exactement, à les redoubler sous une forme déniée qui contribue à les naturaliser. Le principal acquis de ce...

  10. Avant-propos

    Directory of Open Access Journals (Sweden)

    Severiano Rojo Hernandez

    2010-03-01

    Full Text Available Au cours de la première moitié du XXe siècle, l’Europe vit naître et se développer sur son territoire un nombre considérable de dictatures particulièrement sanglantes. Malgré leurs différences idéologiques, Hitler, Staline, Mussolini, Franco, Salazar pratiquèrent une même politique répressive, fondée sur la censure, la terreur, l’élimination des adversaires politiques et la mise sous surveillance de l’ensemble de la société. Comme le signale Giorgio Agamben (« L’Etat d’exception », Le Monde, ...

  11. Avant-propos

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    Mona Huerta

    2011-10-01

    Full Text Available En 2009 se cumplió el setenta aniversario del final oficial de la Guerra Civil, un enfrentamiento que tuvo repercusiones considerables en numerosos países europeos y americanos. Interpretada por algunos como el inicio de la Segunda Guerra mundial, la Guerra Civil fue un acontecimiento fundador para una parte significativa de la población de naciones como Francia, México y Argentina. Por sus consecuencias políticas, culturales y demográficas, este conflicto dejó una huella indeleble y se convi...

  12. Avant-propos

    OpenAIRE

    2015-01-01

    Martine Droulers (CNRS-CREDAL), « océan éthiopien » La dénomination « oceanus aethiopicus » est apparue sur les cartes hollandaises dès le début du xvie siècle (Jansonius, Amsterdam, 1630). Cette expression a perduré dans les atlas jusqu’au xixe siècle. Le mot « aethiopicus » désigne les têtes noires ou faces brûlées, puis la mer qui borde le continent des hommes noirs. Alors que la navigation est essentiellement côtière et la géographie incertaine, l’Afrique exprime de façon cartographique s...

  13. Avant-propos

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    Arlette Gautier

    2008-03-01

    Full Text Available La revue @mnis a décidé de consacrer un numéro spécial à « femmes et militantisme » en hommage à Simone de Beauvoir. Celle-ci s’est engagée contre la guerre d’Algérie puis dans le féminisme radical des années 1970. Ses romans et son œuvre philosophique n’ont cessé de poser la question de l'oppression et de la liberté. Pour elle, l’individu reste libre et responsable même dans une situation oppressive. Une des manifestations de cette liberté peut être le militantisme. Malgré la domination qui ...

  14. Avant-propos

    OpenAIRE

    Prouteau, Anne; Spiquel, Agnès

    2017-01-01

    De 1935 à sa mort, Albert Camus écrit régulièrement dans ses « Cahiers » : laboratoire de l’œuvre, « choses vues », notes de lectures, impressions de voyages, réflexions philosophiques et, de plus en plus vers la fin de sa vie, notations intimes, tout s’y mêle en une mosaïque de styles, du plan de travail à l’aphorisme percutant, du fragment narratif au développement lyrique. Assez tôt, il songe à les faire dactylographier, les faisant ainsi accéder au statut de textes. Il procède alors (les ...

  15. Avant-propos

    OpenAIRE

    Richard, Nathalie

    2017-01-01

    « Histoire et morales » : d’emblée, ainsi que le souligne Delphine Gleizes dans son article, la formule nous confronte à la polysémie. Par-delà celle du premier de ces deux termes, dont l’analyse constitue l’enjeu même d’Écrire l’histoire, s’impose également la multiplicité des significations du mot « morale », que rend sa transcription au pluriel dans l’intitulé des deux numéros de 2010. Dans son sens le plus courant, « morale » désigne la définition du bien et du mal. Le terme se relie alor...

  16. Avant-propos

    Directory of Open Access Journals (Sweden)

    François Moureau

    2002-11-01

    Full Text Available Des grands cimetières sous la lune, les mieux entretenus sont encore les bibliothèques. Ce volume un peu fantomatique est une promenade sentimentale et savante au milieu de ces tombes de cuir et de papier qui ne peuvent revivre un instant que par notre regard et par notre attention passagère. Les bibliothèques sont remplies de livres qu'on ne lit plus, qu'on n'a jamais lu peut-être et de quelques ouvrages qui, par magie ou génie singulier, nous parlent encore une langue déchiffrable. Le livre...

  17. Avant-propos

    Directory of Open Access Journals (Sweden)

    Naomi Wulf

    2010-02-01

    Full Text Available Depuis environ dix ans, les biographies des Pères fondateurs de la nation américaine connaissent un succès populaire sans doute inégalé dans le passé. Certaines sont l’œuvre de spécialistes universitaires de la jeune République américaine, tels Joseph J. Ellis avec Passionate Sage : The Character and Legacy of John Adams (1993, American Sphinx : The Character of Thomas Jefferson (1996, National Book Award, puis Founding Brothers : The Revolutionary Generation (2000, Prix Pulitzer et enfin ...

  18. Avant-propos

    OpenAIRE

    Pinto, Louis

    2017-01-01

    La sociologie de la littérature est un moment de vérité pour une discipline qui se doit de prouver que les armes de la raison peuvent s’appliquer à des choses aussi fines. Dans les travaux récents, on peut, au prix d’une relative simplification, discerner deux voies : une étude structurale de style systématique et une lecture sociologique d’une œuvre déterminée. La recherche de Christian Jouhaud nous renvoie à ces temps anciens où les catégories d’un champ proprement littéraire n’étaient pas ...

  19. Avant-propos

    Directory of Open Access Journals (Sweden)

    Georges Toulouse

    2009-11-01

    Full Text Available Dans la foulée d’une première conférence organisée à Nancy en 2005, se tenait à Montréal, en juin 2008, la 2e conférence du Groupe de recherche francophone sur les troubles musculo-squelettiques (TMS. Organisée par l’IRSST et parrainée par la Société d’ergonomie de langue française (SELF et l’Association canadienne d’ergonomie (ACE, cette conférence, De la recherche à l’action, réunissait plus de 250 participants : chercheurs, praticiens et acteurs des milieux de travail. Tous ont profité ...

  20. Avant-propos

    OpenAIRE

    Bayard, Françoise

    2011-01-01

    L'argent du roi : les finances sous François Ier est l'ouvrage d'un jeune chercheur, Philippe Hamon, maître de conférences à l'Université Rennes II. Il témoigne du renouveau des études financières dans la recherche historique mondiale et d'une experte exploitation de sources on ne peut moins sérielles. L'histoire des finances n'est pas vraiment nouvelle en France. La fin du xixe siècle et le début du xxe ont vu de grands pionniers écrire de remarquables livres qui font encore référence aujour...

  1. Avant-propos

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    Monique DE MATTIA-VIVIES

    2010-09-01

    Full Text Available Le présent volume rassemble les textes des communications présentées lors de la Journée d’Étude intitulée La Production et l’Analyse des discours, qui s’est tenue à Aix-en-Provence (Aix-Marseille Université le 4 décembre 2009 sous l’égide du LERMA.L'énoncé de ce sujet d'étude met l’accent, par le pluriel de sa formulation, sur la variété des types de discours : discours verbal ou non verbal, discours oral ou discours écrit, discours littéraire ou spécialisé (l’on peut dans ce cas se poser la...

  2. Avant-propos

    OpenAIRE

    Mona Huerta; Severiano Rojo Hernandez; Olivier Compagnon

    2011-01-01

    En 2009 se cumplió el setenta aniversario del final oficial de la Guerra Civil, un enfrentamiento que tuvo repercusiones considerables en numerosos países europeos y americanos. Interpretada por algunos como el inicio de la Segunda Guerra mundial, la Guerra Civil fue un acontecimiento fundador para una parte significativa de la población de naciones como Francia, México y Argentina. Por sus consecuencias políticas, culturales y demográficas, este conflicto dejó una huella indeleble y se convi...

  3. Avant-propos

    Directory of Open Access Journals (Sweden)

    Severiano Rojo Hernandez

    2006-09-01

    Full Text Available En ce début de XXIe siècle, de nombreuses cérémonies sont venues rappeler aux sociétés européennes et américaines les conflits majeurs qui ont marqué leur histoire. L’anniversaire du début de la Première Guerre mondiale (2004 et la commémoration de la fin de la Seconde Guerre mondiale (2005 sont autant de dates qui soulignent à quel point la violence est indissociable de leur passé. Les différentes cérémonies consacrées en 2005 à la libération des camps de concentration nazis doivent rappel...

  4. Avant-propos

    Directory of Open Access Journals (Sweden)

    Raymond Jamous

    2010-04-01

    Full Text Available Depuis sa création à l’université Paris X-Nanterre par Éric de Dampierre, le Diplôme d’études approfondies (dea d’ethnologie et de sociologie comparative, d’ethnomusicologie et de préhistoire exige des candidats qu’ils présentent un projet de thèse et un article publiable sur un sujet ne relevant pas du domaine de recherches proposé pour la thèse. Ces deux travaux nécessitent une bonne maîtrise des outils conceptuels et constituent chacun un exercice particulier. Le projet de thèse consiste ...

  5. Avant-Propos

    Science.gov (United States)

    Ollivier, J.; Farhi, E.; Ferrand, M.; Benoit, M.

    2005-11-01

    L'École Thématique “Neutrons et Biologie” s'est tenue du 22 au 26 Mai 2004 à Praz/Arly (Haute-Savoie, France), dans le cadre des 12 èmes Journees de la Diffusion Neutronique de la Societe Française de Neutronique. Cette école a ete organisee avec le concours financier du CNRS (formation permanente), du Laboratoire Léon Brillouin (CEA Saclay), de la region Rhône-Alpes, du conseil général de Haute-Savoie et de l'Université Joseph Fourier de Grenoble. Une cinquantaine de participants, dont une vingtaine d'intervenants, ont largement contribué à la réussite de l'École. D'un point de vue scientifique, l'École s'est déclinée en sept sessions thématiques majeures: - une première session introductive a été consacrée à une revue globale des méthodes biophysiques ayant un fort impact pour l'étude de la structure et de la dynamique des macromolécules biologiques (J. Parello). Un accent tout particulier à été apporté pour décrire les neutrons en tant que composante importante de la panoplie des techniques couramment utilisées en biophysique moléculaire (J. Schweitzer). - une session dédiée aux mesures dynamiques par diffusion incohérente de neutrons a été largement developpée. Qu'ils s'agissent de vibrations et de relaxations moléculaires dans les protéines (J.M. Zanotti), de dynamique globale des protéines (G. Zaccaï), ainsi que de dynamique de l'eau d'hydratation (F. Gabel), de nombreux exemples ont permis d'illustrer la pertinence des neutrons pour étudier la dynamique fonctionnelle des protéines sur l'échelle de temps picosecond nanoseconde. L'analyse des données de diffusion inélastique de neutrons ne peut se passer de modélisation théorique analytique des propriétés dynamique des biomolécules (D. Bicout). - une large place avait été réservée aux études structurales en biologie. Cette troisième session a rassemblé des contributions en diffusion aux petits angles de neutrons pour l'étude structurale en solution (D. Lairez), en réflectométrie de neutrons pour l'étude de systèmes des membranes ou de protéines en interaction avec des membranes (G. Fragneto), ainsi qu'en diffraction de fibres appliquée à l'étude de l'ADN (T. Forsyth). - les simulations de dynamique moléculaire constituent une méthode théorique unique pour étudier, au niveau atomique, les mouvements internes des macromolécules biologiques, que ce soit à l'équilibre (G. Kneller, S. Crouzy) ou hors équilibre (B. Gilquin). Les trajectoires de dynamique moléculaire s'étendent aujourd'hui à la centaine de nanosecondes, et peuvent être de ce fait utilisées par certains programmes pour calculer les observables expérimentales fournies par la diffusion de neutrons (G. Kneller, T. Hinsen). - l'ouverture des neutrons à des techniques instrumentales permettant d'approcher, d'une part, des états hors-équilibre par le biais d'études cinétiques couplées à des mélanges rapides pour des études de croissance de phases (I. Grillo) ou de repliement de protéines, d'autre part, des conditions expérimentales extrèmes (hautes-pressions, M. Plazanet), nous ont semblé constituer des émergences prometteuses. À ce titre, une revue sur le repliement des protéines (V. Forge) a précisé l'importance de nombreuses techniques (fluorescence intrinsèque, dichroïsme, infra-rouge, RMN) dans le domaine, tout en permettant d'entrevoir l'intérêt des études par neutrons. - en marge des sessions purement “neutrons”, il nous semblait important de pouvoir présenter des techniques et méthodes souvent reconnues comme très complémentaires des neutrons, en privilégiant un volet “études structurales” et un volet “études dynamiques”. Côté méthodes dynamiques, la RMN (M. Blackledge) a été positionnée comme une technique permettant d'étudier la flexibilité moléculaire sur des echelles de temps plus lentes (ms). Côté méthodes structurales, la bio-cristallographie des RX appliquée à l'études des structures virales (P. Gouet) a permis de mettre en évidence des aspects complémen

  6. Avant-propos

    OpenAIRE

    2013-01-01

    Longtemps, j’ai rêvé ce livre. Au moment où j’en rédige la première – et dernière – page, ma pensée va à tous ceux qui m’ont accompagné dans cette longue et difficile enquête. Et d’abord à Pierre Grimal, savant et maître incomparable : en dédiant ce livre à sa chère mémoire, je souhaite rendre hommage à celui qui fut à l’origine de ma vocation, qui dirigea ces recherches jusqu’à sa disparition, et dont la bienveillance et l’amitié ont été et restent pour moi le plus précieux des encouragement...

  7. Avant-propos

    OpenAIRE

    Chantepie, Philippe

    2015-01-01

    Le « livre numérique ». L’expression est commode pour rappeler une réalité presque ancienne, décrire des marchés naissants, concentrer les stratégies des acteurs nationaux de l’industrie de l’édition et de sa distribution, appeler l’attention plus récente des politiques publiques, s’épanouir avec les nouveautés techniques d’accès au texte numérique. Le livre numérique recouvre une réalité présente très incertaine, a fortiori du futur, tant il est probable que le livre numérique ne sera pas le...

  8. Avant-propos

    Directory of Open Access Journals (Sweden)

    Valérie AUDA-ANDRÉ

    2009-07-01

    Full Text Available La question de l’état de la démocratie britannique bénéficie à l’heure actuelle d’un haut degré de visibilité dans les médias ; elle fait l’objet d’une série de commentaires et d’initiatives émanant du gouvernement et plus largement de la classe politique mais aussi d’associations de la société civile et de groupes de pression. Cette préoccupation soudaine, teintée d’une inquiétude qui peut s’avérer éphémère tant elle est dictée par l’actualité, nous invite toutefois à tenter de remonter aux origines de la rupture de la « démocratie d’équilibre ». Nous suivrons les transformations du régime démocratique britannique de la démocratie de marché des années Thatcher et Major à la démocratie participative et aux nouveaux schémas de gouvernance mis en œuvre par New Labour. Ce panorama sera l’occasion d’une réflexion théorique sur les différentes stratégies d’adaptation du modèle démocratique aux mutations sociales, économiques et culturelles qui ont modifié en profondeur l’identité du peuple britannique, l’être collectif qui se réalise dans des institutions et une pratique démocratiques.

  9. Avant-propos

    OpenAIRE

    Lamloum, Olfa

    2010-01-01

    Depuis maintenant plus de deux décennies, la recherche consacrée aux mouvements islamistes a connu, en France comme ailleurs, un développement notable . Elle a porté sur les références doctrinales et idéologiques des différentes composantes de l’islamisme, elle a analysé leurs trajectoires politiques et leurs rapports à l’Etat, scruté leurs répertoires d’action, considéré leur inscription dans les multiples sociétés politiques dont elles sont l’émanation ou encore, plus récemment, étudié leur...

  10. Avant-propos Foreword

    Directory of Open Access Journals (Sweden)

    Annick Cizel

    2009-06-01

    Full Text Available Jamais le texte n’est singulier, qui se construit plutôt dans une entreprise d’individualité collective enrichie d’intertextualité.  Nourri d’entrelacs littéraires, il est le reflet de perspectives picturales, s’étoffe de rémanences socio-culturelles, traduit les déterminismes personnels et territoriaux, convoque ce que Michel Feith nomme, à la manière d’Edouard Glissant, la « poétique du divers ». Nourris d’une Amérique-concept, multiple par essence, les onze textes qui suivent ne sont jamai...

  11. Avant-propos

    OpenAIRE

    Fuchs, Catherine

    2017-01-01

    Le programme Cognitique du ministère de la Recherche (1999-2002) avait pour objectif principal de favoriser les collaborations entre, d’une part, les sciences du cerveau et/ou le secteur de l’informatique et, d’autre part, les sciences humaines et sociales. À cet effet, dix appels à projets ont été lancés par le programme. Le tout premier, initié en 1999, portait sur le thème de « la cognition spatiale » ; un autre, impulsé en 2001, sur le thème de « l’action ». Le lien étroit entre ces deux ...

  12. Avant-propos

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    Georges Martin

    2010-06-01

    Full Text Available Ce numéro 9 de la revue e-Spania réunit, sous l’égide d’AILP (GDRE 671 du CNRS et du SEMH-Sorbonne (CLEA, EA 4083, un ensemble d’études portant sur le Liber regum (ou Libro de las generaciones y linajes de los reyes. Ces articles constituent la version remaniée et expertisée de communications présentées lors d’un colloque qui s’est tenu en Sorbonne les 4 et 5 décembre 2009 sous le titre Historiographie royale léonaise, castillane et navarraise du XIIe siècle. 2 : le Liber regum. Coordonnée...

  13. Applications of cerebral SPECT

    Energy Technology Data Exchange (ETDEWEB)

    McArthur, C., E-mail: claire.mcarthur@nhs.net [Department of Neuroradiology, Institute of Neurological Sciences, Glasgow (United Kingdom); Jampana, R.; Patterson, J.; Hadley, D. [Department of Neuroradiology, Institute of Neurological Sciences, Glasgow (United Kingdom)

    2011-07-15

    Single-photon emission computed tomography (SPECT) can provide three-dimensional functional images of the brain following the injection of one of a series of radiopharmaceuticals that crosses the blood-brain barrier and distributes according to cerebral perfusion, neurotransmitter, or cell density. Applications include differentiating between the dementias, evaluating cerebrovascular disease, preoperative localization of epileptogenic foci, diagnosing movement disorders, and evaluation of intracerebral tumours, while also proving a useful research tool. Unlike positronemission tomography (PET), SPECT imaging is widely available and can be performed in any department that has access to a rotating gamma camera. The purpose of this review is to demonstrate the utility of cerebral SPECT and increase awareness of its role in the investigation of neurological and psychiatric disorders.

  14. Plasticidad cerebral y lenguaje

    OpenAIRE

    Moreno-Torres Sánchez, Ignacio; Berthier Torres, Marcelo Luís

    2012-01-01

    Hace pocos años se daba por sentado que la recuperación del lenguaje tras una lesión cerebral era imposible, al igual que adquirir la lengua materna más allá de los tres primeros años de vida. Sin embargo, las últimas indagaciones muestran que nuestra capacidad de aprender es mucho mayor.

  15. Cerebral palsy and aging

    OpenAIRE

    Haak, Peterson; Lenski, Madeleine; Hidecker, Mary Jo Cooley; Li, Min; Paneth, Nigel

    2009-01-01

    Cerebral palsy (CP), the most common major disabling motor disorder of childhood, is frequently thought of as a condition that affects only children. Deaths in children with CP, never common, have in recent years become very rare, unless the child is very severely and multiply disabled. Thus, virtually all children assigned the diagnosis of CP will survive into adulthood. Attention to the adult with CP has been sparse, and the evolution of the motor disorder as the individual moves through ad...

  16. High Altitude Cerebral Edema

    Science.gov (United States)

    1986-03-01

    reflected a cerebral form of high altitude illness. In 1964, Fitch described a similar form of mountain sickness with neurolkgical manifestations in the...71% in thaL of Hackett et al; this sex distribution undoubtedly reflects the larger numbers of males presently involved in trekking and 44...HACE with loss of consciousness, absence of pupillary reactions, flaccidity of all extremities and the presence of bilateral Babinski responses. The

  17. Cerebral oxygenation and hyperthermia

    Directory of Open Access Journals (Sweden)

    Anthony Richard Bain

    2014-03-01

    Full Text Available Hyperthermia is associated with marked reductions in cerebral blood flow (CBF. Increased distribution of cardiac output to the periphery, increases in alveolar ventilation and resultant hypocapnia each contribute to the fall in CBF during passive hyperthermia; however, their relative contribution remains a point of contention, and probably depends on the experimental condition (e.g. posture and degree of hyperthermia. The hyperthermia-induced hyperventilatory response reduces arterial CO2 pressure (PaCO2 causing cerebral vasoconstriction and subsequent reductions in flow. During supine passive hyperthermia, the majority of recent data indicate that reductions in PaCO2 may be the primary, if not sole, culprit for reduced CBF. On the other hand, during more dynamic conditions (e.g. hemorrhage or orthostatic challenges, an inability to appropriately decrease peripheral vascular conductance presents a condition whereby adequate cerebral perfusion pressure may be compromised secondary to reductions in systemic blood pressure. Although studies have reported maintenance of pre-frontal cortex oxygenation (assessed by near-infrared spectroscopy during exercise and severe heat stress, the influence of cutaneous blood flow is known to contaminate this measure. This review discusses the governing mechanisms associated with changes in CBF and oxygenation during moderate to severe (i.e. 1.0°C to 2.0°C increase in body core temperature levels of hyperthermia. Future research directions are provided.

  18. Cerebral malformations without antenatal diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Girard, Nadine J. [Diagnostic Neuroradiology, Hopital Timone, Marseille (France)

    2010-06-15

    Cerebral malformations are usually described following the different steps in development. Disorders of neurulation (dysraphisms), or diverticulation (holoprosencephalies and posterior fossa cysts), and total commissural agenesis are usually diagnosed in utero. In contrast, disorders of histogenesis (proliferation-differentiation, migration, organization) are usually discovered in infants and children. The principal clinical symptoms that may be a clue to cerebral malformation include congenital hemiparesis, epilepsy and mental or psychomotor retardation. MRI is the imaging method of choice to assess cerebral malformations. (orig.)

  19. Hyperventilation, cerebral perfusion, and syncope.

    Science.gov (United States)

    Immink, R V; Pott, F C; Secher, N H; van Lieshout, J J

    2014-04-01

    This review summarizes evidence in humans for an association between hyperventilation (HV)-induced hypocapnia and a reduction in cerebral perfusion leading to syncope defined as transient loss of consciousness (TLOC). The cerebral vasculature is sensitive to changes in both the arterial carbon dioxide (PaCO2) and oxygen (PaO2) partial pressures so that hypercapnia/hypoxia increases and hypocapnia/hyperoxia reduces global cerebral blood flow. Cerebral hypoperfusion and TLOC have been associated with hypocapnia related to HV. Notwithstanding pronounced cerebrovascular effects of PaCO2 the contribution of a low PaCO2 to the early postural reduction in middle cerebral artery blood velocity is transient. HV together with postural stress does not reduce cerebral perfusion to such an extent that TLOC develops. However when HV is combined with cardiovascular stressors like cold immersion or reduced cardiac output brain perfusion becomes jeopardized. Whether, in patients with cardiovascular disease and/or defect, cerebral blood flow cerebral control HV-induced hypocapnia elicits cerebral hypoperfusion, leading to TLOC, remains to be established.

  20. Cerebral Autoregulation in Normal Pregnancy and Preeclampsia

    NARCIS (Netherlands)

    van Veen, Teelkien R.; Panerai, Ronney B.; Haeri, Sina; Griffioen, Annemiek C.; Zeeman, Gerda; Belfort, Michael A.

    2013-01-01

    OBJECTIVE: To test the hypothesis that preeclampsia is associated with impaired dynamic cerebral autoregulation. METHODS: In a prospective cohort analysis, cerebral blood flow velocity of the middle cerebral artery (determined by transcranial Doppler), blood pressure (determined by noninvasive

  1. Genetics Home Reference: cerebral cavernous malformation

    Science.gov (United States)

    ... Twitter Home Health Conditions Cerebral cavernous malformation Cerebral cavernous malformation Printable PDF Open All Close All Enable ... to view the expand/collapse boxes. Description Cerebral cavernous malformations are collections of small blood vessels ( capillaries ) ...

  2. Cerebral oxygenation after birth

    DEFF Research Database (Denmark)

    Hessel, Trine W; Hyttel-Sorensen, Simon; Greisen, Gorm

    2014-01-01

    AIM: To compare absolute values of regional cerebral tissue oxygenation (cStO2 ) during haemodynamic transition after birth and repeatability during steady state for two commercial near-infrared spectroscopy (NIRS) devices. METHODS: In a prospective observational study, the INVOS 5100C and FORE......: The INVOS and FORE-SIGHT cStO2 estimates showed oxygenation-level-dependent difference during birth transition. The better repeatability of FORE-SIGHT could be due to the lower response to change in saturation....

  3. Oligodendrogenesis after Cerebral Ischemia

    Directory of Open Access Journals (Sweden)

    Ruilan eZhang

    2013-10-01

    Full Text Available AbstractNeural stem cells in the subventricular zone (SVZ of the lateral ventricle of adult rodent brain generate oligodendrocyte progenitor cells (OPCs that disperse throughout the corpus callosum and striatum where some of OPCs differentiate into mature oligodendrocytes. Studies in animal models of stroke demonstrate that cerebral ischemia induces oligodendrogenesis during brain repair processes. This article will review evidence of stroke-induced proliferation and differentiation of OPCs that are either resident in white matter or are derived from SVZ neural progenitor cells and of therapies that amplify endogenous oligodendrogenesis in ischemic brain.

  4. Hemodynamics of Cerebral Aneurysms

    Science.gov (United States)

    Sforza, Daniel M.; Putman, Christopher M.; Cebral, Juan Raul

    2009-01-01

    The initiation and progression of cerebral aneurysms are degenerative processes of the arterial wall driven by a complex interaction of biological and hemodynamic factors. Endothelial cells on the artery wall respond physiologically to blood-flow patterns. In normal conditions, these responses are associated with nonpathological tissue remodeling and adaptation. The combination of abnormal blood patterns and genetics predisposition could lead to the pathological formation of aneurysms. Here, we review recent progress on the basic mechanisms of aneurysm formation and evolution, with a focus on the role of hemodynamic patterns.

  5. Cerebral aneurysms – an audit

    African Journals Online (AJOL)

    Enrique

    Abstract. We performed an audit to determine the profile of cerebral aneurysms at the Universitas Hospital Bloem- fontein, the only government hospital with a vascular suite in the Free State and Northern Cape area. Two hun- dred and twenty-three government patients, diagnosed with cerebral aneurysms during the period.

  6. Hyperventilation, cerebral perfusion, and syncope

    DEFF Research Database (Denmark)

    Immink, R V; Pott, F C; Secher, N H

    2014-01-01

    This review summarizes evidence in humans for an association between hyperventilation (HV)-induced hypocapnia and a reduction in cerebral perfusion leading to syncope defined as transient loss of consciousness (TLOC). The cerebral vasculature is sensitive to changes in both the arterial carbon...

  7. Therapeutic interventions in cerebral palsy.

    Science.gov (United States)

    Patel, Dilip R

    2005-11-01

    Various therapeutic interventions have been used in the management of children with cerebral palsy. Traditional physiotherapy and occupational therapy are widely used interventions and have been shown to be of benefit in the treatment of cerebral palsy. Evidence in support of the effectiveness of the neurodevelopmental treatment is equivocal at best. There is evidence to support the use and effectiveness of neuromuscular electrical stimulation in children with cerebral palsy. The effectiveness of many other interventions used in the treatment of cerebral palsy has not been clearly established based on well-controlled trials. These include: sensory integration, body-weight support treadmill training, conductive education, constraint-induced therapy, hyperbaric oxygen therapy, and the Vojta method. This article provides an overview of salient aspects of popular interventions used in the management of children with cerebral palsy.

  8. Niš music festival and avant-garde music: Case studies concert of the Radio Belgrade Electronic Studio and 'John Cage's Evening'

    Directory of Open Access Journals (Sweden)

    Cvetković Sonja S.

    2017-01-01

    Full Text Available In the period of domination of socialist realism and moderate modernism, which meant for the Serbian post-war musical creativity isolation from the European and world trends of musical avant-garde, during the sixties and seventies of the twentieth century music of the Serbian and Yugoslav composers of the younger generation becomes more open to a new sound concepts of serialism, aleatory, electronic media and minimalism. A radical break with tradition and changes in almost all aspects of the new music - aesthetics, notation, sound realization - made difficult to establish a clear criteria for its evaluation and therefore, the general reception of the most actual tendencies. Beside two institutional musical places where the contemporary world and national music was performed and promoted - International Music Biennale Zagreb, founded in 1961 and annual Review of Yugoslav Music in Opatija, founded in 1964 (since 1979 under the name Review of Musical Creativity of Yugoslavia, concert and festival stages in the leading musical centers in former Yugoslavia have shown considerable restraint to the contemporary music. In the case of the reception of electro-acoustic compositions created in the Radio Belgrade Electronic Studio and John Cage's sonatas for prepared piano that were performed at the Niš (October Music Festival during the eighties of the 20th century, the paper discusses about the representation of avant-garde music at this manifestation and openness of the local public towards the contemporary compositional streams. At the concert held in 1981 in the hall of the Niš Symphony Orchestra were presented the latest achievements of the composers Miloš Petrović (Anton with or without Webern, 1981, Paul Pignon (Cartoon, 1980, Janez Matičič (Fusions, 1979, Vladan Radovanović (Audiospacial, 1975-78 and Dragoslav Ortakov (Eleorp, 1976 realized in the Radio Belgrade Electronic Studio founded in 1971. Serbian pianist Nada Kolundžija performed in

  9. Cerebral imaging in pediatrics

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, I. [London, Great Ormond Street Hospital for Children (United Kingdom)

    1998-06-01

    Radioisotope brain imaging has focused mainly on regional cerebral blood flow (rCBF). However the use of ligand which go to specific receptor sites is being introduced in pediatrics, mainly psychiatry. rCBF is potentially available in many institutions, especially with the availability of multi-headed gamma cameras. The use of this technique in pediatrics requires special attention to detail in the manner of data acquisition and handling the child. The interpretation of the rCBF study in a child requires knowledge of normal brain maturation. The major clinical use in pediatrics is epilepsy because of the advances in surgery and the frequency of complex partial seizures. Other indications in pediatric neurology include brain death, acute neurological loss including stroke, language disorders, cerebral palsy, hypertension due to renovascular disease, traumatic brain injury and migraine. There are pediatric physiological conditions in which rCBF has been undertaken, these include anorexia nervosa, autism, Gilles de la Tourette syndrome (GTS) and attention deficit disorder-hyperactivity (ADHD). Research using different ligands to specific receptor sites will also be reviewed in pediatrics.

  10. Cerebral cartography and connectomics.

    Science.gov (United States)

    Sporns, Olaf

    2015-05-19

    Cerebral cartography and connectomics pursue similar goals in attempting to create maps that can inform our understanding of the structural and functional organization of the cortex. Connectome maps explicitly aim at representing the brain as a complex network, a collection of nodes and their interconnecting edges. This article reflects on some of the challenges that currently arise in the intersection of cerebral cartography and connectomics. Principal challenges concern the temporal dynamics of functional brain connectivity, the definition of areal parcellations and their hierarchical organization into large-scale networks, the extension of whole-brain connectivity to cellular-scale networks, and the mapping of structure/function relations in empirical recordings and computational models. Successfully addressing these challenges will require extensions of methods and tools from network science to the mapping and analysis of human brain connectivity data. The emerging view that the brain is more than a collection of areas, but is fundamentally operating as a complex networked system, will continue to drive the creation of ever more detailed and multi-modal network maps as tools for on-going exploration and discovery in human connectomics. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  11. New cerebral protection strategies.

    Science.gov (United States)

    Thal, Serge C; Engelhard, Kristin; Werner, Christian

    2005-10-01

    This article presents an overview of the most recent and important strategies to reduce secondary brain damage. There is currently no magic bullet available to protect the brain after neuronal injury. This is related to the complex pathophysiology of cerebral ischemia, which makes it unlikely that a single pharmacological intervention results in sustained neuroprotection. Analyses of clinical studies reveal that acute physiologic derangements (e.g. fever, hypertension and hypotension, hypoxemia, hypercapnia, hyperglycemia) are the most important predictors of unfavorable outcome after brain injury and have to be treated. The effectiveness of anesthetic agents to extend the ischemic tolerance of neurons has been demonstrated in experimental settings, but such benefits have not been demonstrated in humans. The effectiveness of osmodiuretics to decrease elevated intracranial pressure, a factor with relevance to outcome, has been demonstrated. Infusion of magnesium in patients with subarachnoidal hemorrhage can reduce the occurrence of delayed ischemia caused by cerebrovascular spasm. The prophylactic administration of glucocorticoids should be avoided. While the positive effects of chronic administration of statins to reduce the incidence of stroke has been demonstrated in several clinical studies, the protective effect of acute administration of statins after a cerebral insult has do be defined. Control of physiological variables, avoidance of hyperthermia, intensive control of plasma glucose concentrations, use of anesthetic agents and osmodiuretics to control intracranial hypertension and the possible prophylactic administration of magnesium in patients at risk of vasospasm and of statins in patients with cerebrovascular risk factors are currently the most important strategies to reduce neuronal injury.

  12. Phonemes, Graphemes, Dabs of Paint: Roman Jakobson, the Russian avant-garde and the search for the shared basic elements of painting and poetry

    Directory of Open Access Journals (Sweden)

    Hofstede, Bregje

    2012-03-01

    Full Text Available The subject of this paper is the supposed affinity between painting and poetry as theorised by the linguist Roman Jakobson who played a crucial role for the Russian avant-garde and its close association of painting and poetry. The paper focuses on Jakobson's relation to the two 1913 manifestos "The Word as Such" and "The Letter as Such", written by the poets Chlebnikov and Kruchenyck, and on Jakobson's own (lost reply. It calls into question the accuracy of Jakobson's claim of having influcenced the poets' manifestos, and describes what Jakobson considered to be the shared 'core elements' of the visual and literary arts. According to him, they share a visuality, not on the level of the written sign or grapheme, but on a deeper level, visible only to the mind's eye.

  13. Dissonant Echoes of the Great War: Avant-garde, Urban Space, and Immigrant Voices in Armando Discépolo’s Babilonia

    Directory of Open Access Journals (Sweden)

    Gorica Majstorovic

    2014-04-01

      The present essay proposes that the problem of WWI is central to the "dissemination" trope of the Argentine cultural production in the 1920’s. The trope is examined in relation to modernity and urban space, in Armando Discépolo’s Babilonia (1925 and Xul Solar’s "Puerto" paintings (1923-1925. Through a contextualized reading of Babilonia, the essay analyzes the disseminated nationalities and languages, at a time when post WWI European immigrants presented a "threat" to national purity. Babylonian trope is associated with images of distraction, dissemination, and destruction. This is of particular importance for the analysis, especially with regard to the presence of Babylonian "dissemination" trope alongside criollismo and the emergent avant-garde currents in Argentina (Duchamp in Buenos Aires 1918-19, Marinetti in 1926, Borges, Girondo.

  14. Cerebral Palsy: An Overview.

    Science.gov (United States)

    Gulati, Sheffali; Sondhi, Vishal

    2017-11-20

    Cerebral palsy (CP) is a neurodevelopmental disorder characterized by abnormalities of muscle tone, movement and motor skills, and is attributed to injury to the developing brain. The clinical features of this entity evolve over time and the specific CP syndrome may be recognizable only after 3-5 y of age; although suggestive signs and symptoms may be present at an earlier age. The management involves neurological rehabilitation (addressing muscle tonal abnormalities, and devising physical and occupational therapies) and diagnosis and management of co-morbidities (including epilepsy, impairment of cognition, vision, hearing, and disturbances of growth and gastrointestinal function). The management, therefore, is multidisciplinary involving the treating physician working with a team of rehabilitation-, orthopedic-, psychologic-, and social care- providers.

  15. Cerebral toxoplasmosis in AIDS

    Energy Technology Data Exchange (ETDEWEB)

    Christ, F.; Steudel, H.; Klotz, D.

    1986-02-01

    Since 1982 (Hauser and co-workers), literature has reported focal cerebral tissue charges in AIDS patients whose diagnosis was unclear at first but which could be identified finally as florid toxoplasmosis encephalitis by biopsy and autopsy. It was found that the value of otherwise reliable serological tests (KBR, Sabin-Feldmann tests, etc.) is questionable in patients with severely impaired or incompetent immune systems, and, in particular, that a negative or uncharacteristic test result may not preclude any opportunistic infection process. Furthermore, isolation of Toxoplasma gondii or specific antibodies from the cerebrospinal fluid will be successful in exceptional cases only. In patients with AIDS or lymphadenopathy syndrome, the differential diagnosis will have to include - first and foremost - reactivated toxoplasma infection (not newly acquired, as a rule) if central neurological symptoms occur.

  16. Les accidents vasculaires cerebraux ischemiques compliquant l ...

    African Journals Online (AJOL)

    Conclusion: Les accidents ischémiques consécutifs à l'arrêt du traitement anticoagulant dans les hémorragies cérébrales sont rares mais graves. Leur prise en charge constitue pour les praticiens un dilemme. Mots clés: AVC ischémique - Arrêt anticoagulant- Hématome intracrânien. English Title: Ischemic stroke ...

  17. Epidemiologie des accidents vasculaires cerebraux dans la ...

    African Journals Online (AJOL)

    Stroke is the third cause of death among hospitalized patients and the first aetiology of permanent physical disability throughout the world. They are public health problem not also in developed countries but also in developing ones. Aims of the study: The aim of this study was the feasibility and the installation of stroke ...

  18. aspects tissulaires, vasculaires, cellulaires et biochimiques

    OpenAIRE

    Quéré, Nadine

    2010-01-01

    Dissertação de Mestrado apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Psicopedagogia Perceptiva. Ce mémoire présente une exploration de certaines recherches scientifiques concernant les fascias afin d’éclairer les impacts cellulaires et biochimiques du geste thérapeutique manuel en fasciathérapie Méthode Danis Bois. Ma recherche s’est effectuée à partir de publications récentes : ouvrages, documents Internet et articles ...

  19. Cerebral venous thrombosis.

    Science.gov (United States)

    Ferro, José Manuel; Canhão, Patrícia; Aguiar de Sousa, Diana

    2016-12-01

    Cerebral venous thrombosis (CVT) has an incidence of 1.32/100,000/years in high-income countries, and higher in middle- and low-income countries. CVT is more frequent in infants and children young adults and females, especially during pregnancy/puerperium. CVT are now being diagnosed with increasing frequency because of the increased awareness and higher use of magnetic resonance imaging (MR) for investigating patients with acute and subacute headaches and new onset seizures. CVT rarely present as a stroke syndrome. Their most frequent presentations are isolated headache, intracranial hypertension syndrome, seizures, a lobar syndrome and encephalopathy. The confirmation of the diagnosis of CVT relies on the demonstration of thrombi in the cerebral veins and/or sinuses by MR/MR venography or veno CT. The more frequent risk factors/associated conditions for CVT are genetic prothrombotic conditions, antiphospholipid syndrome and other acquired prothrombotic diseases, including cancer, oral contraceptives, puerperium and pregnancy, infections and trauma. The prognosis of CVT is in general favorable, as acute death rate is below 5% and only 15% of the patients remain dependent or die. Treatment in the acute phase includes management of the associated condition, anticoagulation with either low molecular weight or unfractionated heparin, treatment of intracranial hypertension, prevention of recurrent seizures and headache relief. In patients in severe condition on admission or who deteriorate despite anticoagulation, local thrombolysis or thrombectomy is an option. Decompressive surgery is lifesaving in patients with large venous infarcts or hemorrhage with impending herniation. After the acute phase, patients should anticoagulated for a variable period of time, depending on their inherent thrombotic risk. CVT patients may experience recurrent seizures. Prophylaxis with anti-epileptic drugs is recommended after the first seizure, in those with hemispheric lesions. There

  20. Tacrolimus prevents murine cerebral malaria.

    Science.gov (United States)

    Bao, Lam Quoc; Nhi, Dang My; Huy, Nguyen Tien; Hamano, Shinjiro; Hirayama, Kenji

    2017-02-01

    Tacrolimus and mycophenolate mofetil are immunosuppressants frequently used in human organ transplantation. Tacrolimus is also reported to inhibit Plasmodium falciparum growth in vitro. Here, we report that tacrolimus prevented the death from cerebral malaria of Plasmodium berghei ANKA-infected C57BL/6J mice, but not their death from malaria due to the high parasitaemia and severe anaemia. The mycophenolate mofetil-treated mice showed higher mortality from cerebral malaria and succumbed to malaria earlier than tacrolimus-treated littermates. Tacrolimus attenuated the infiltration of mononuclear cells including pathogenic CD8+ T cells into the brain. It appears to prevent murine cerebral malaria through the inhibition of cerebral infiltration of CD8+ T cells. © 2016 John Wiley & Sons Ltd.

  1. Scoliosis in Spastic Cerebral Palsy

    OpenAIRE

    J Gordon Millichap

    1998-01-01

    The natural history and risk factors for progressive severe scoliosis were evaluated in 37 institutionalized spastic cerebral palsy patients followed at the Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, and at Centers in Nagano, Japan.

  2. [Senile macula and cerebral functions].

    Science.gov (United States)

    Offret, G; Dhermy, P

    1984-01-01

    Because of similarities in the physiology and histology of the intraocular and the cerebral circulations, a study of cerebral disorders in patients with senile macular choroidal degeneration (S.M.C.D.) was undertaken. Of 26 cases of S.M.C.D. with sufficient follow-up, 7 showed signs of cerebral disfunction. Types of problems most often found were inordinate disturbances of short-term memory, judgement, and social behavior. It appears that S.M.C.D. tends more to be associated with mental involution than with sensory-motor deficits. Various methods of investigating the cerebro-vascular circulation can be helpful in discussing causes of mental involution, including doppler ultrasound, echotomography Xemon 133 inhalation, positron emission tomography, C.T. scanning, and nuclear magnetic resonance scanning. The physiopathology may involve relative cerebral ischemia, modification of neurotransmitters, and free radical formation, as well as immunologic factors. Specific treatment may one day become reality.

  3. Learn More About Cerebral Palsy

    Centers for Disease Control (CDC) Podcasts

    2008-03-30

    This podcast describes the causes, preventions, types, and signs and symptoms of cerebral palsy.  Created: 3/30/2008 by National Center on Birth Defects and Developmental Disabilities.   Date Released: 3/21/2008.

  4. Cerebral and Sinus Vein Thrombosis

    Science.gov (United States)

    ... The typical target INR is 2.0 to 3.0. One of the newer oral blood thinners (rivaroxaban [ ... the Council on Epidemiology and Prevention . Diagnosis and management of cerebral venous thrombosis: a statement for healthcare ...

  5. CEREBRAL PALSY : ANTENATAL RISK FACTORS

    OpenAIRE

    Srinivasa Rao; Vidyullatha; Subbalakshmi

    2015-01-01

    INTRODUCTION: Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Cerebral palsy is caused by abnormal development or damage to the parts of the brain that control movement, balance, and posture. Most often the problems occur during pregnancy; however, they may also occur during childbirth, or shortly after birth. Often the cause is unknown. AIM: To study the different antenatal maternal risk factors associated with cere...

  6. Parálisis cerebral :

    OpenAIRE

    Aguado Navarro, Ana Belén

    2013-01-01

    Se aborda el tema de la parálisis cerebral definiendo qué es, clasificando los tipos de parálisis dependiendo de la afectación y las características principales. Se explican algunos de sus tratamientos, se dan sistemas alternativos y/o aumentativos de comunicación para un alumno con PC (parálisis cerebral).

  7. Cerebral candidiasis. Computed tomography appearance

    Energy Technology Data Exchange (ETDEWEB)

    Chaabane, M.; Ladeb, M.F.; Bouhaouala, M.H.; Ben Hammouda, M.; Ataalah, R.; Gannouni, A.; Krifa, H.

    1989-07-01

    A three year old child who had been suffering from oral candidiasis since the age of 1 year presented with osteitis of the clavicle, 2 cerebral frontal abscesses and an occipital abscess which extended across the calvaria and was associated with osteolysis. Histological and microbiological studies following surgery confirmed the diagnosis of candidiasis in this girl who was found to have IgA immunodefinciency. The authors report the computed tomographic appearance of the cerebral lesions and review the literature. (orig.).

  8. Cerebral trypanosomiasis and AIDS

    Directory of Open Access Journals (Sweden)

    Antunes Apio Claudio Martins

    2002-01-01

    Full Text Available A 36 year-old black female, complaining of headache of one month's duration presented with nausea, vomiting, somnolence, short memory problems, loss of weight, and no fever history. Smoker, intravenous drugs abuser, promiscuous lifestyle. Physical examination: left homonimous hemianopsia, left hemiparesis, no papilledema, diffuse hyperreflexia, slowness of movements. Brain CT scan: tumor-like lesion in the splenium of the corpus calosum, measuring 3.5 x 1.4 cm, with heterogeneous enhancing pattern, sugesting a primary CNS tumor. Due to the possibility of CNS infection, a lumbar puncture disclosed an opening pressure of 380 mmH(20; 11 white cells (lymphocytes; glucose 18 mg/dl (serum glucose 73 mg/dl; proteins 139 mg/dl; presence of Trypanosoma parasites. Serum Elisa-HIV tests turned out to be positive. Treatment with benznidazole dramatically improved clinical and radiographic picture, but the patient died 6 weeks later because of respiratory failure. T. cruzi infection of the CNS is a rare disease, but we have an increasing number of cases in HIV immunecompromised patients. Diagnosis by direct observation of CSF is uncommon, and most of the cases are diagnosed by pathological examination. It is a highly lethal disease, even when properly diagnosed and treated. This article intends to include cerebral trypanosomiasis in the differential diagnosis of intracranial space-occupying lesions, especially in immunecompromised patients from endemic regions.

  9. Pseudotumoral delayed cerebral radionecrosis

    Energy Technology Data Exchange (ETDEWEB)

    Ciaudo-Lacroix, C.; Lapresle, J. (Centre Hospitalier de Bicetre, 94 - Le Kremlin-Bicetre (France))

    1985-01-01

    A 60 year-old woman with a scalp epithelioma underwent radiotherapy, the dose being 57 Gray. A first epileptic seizure occurred twenty months later. Neurological examination revealed signs of left hemisphere involvement. ..gamma..EG, angiography, CT scans, demonstrated a pseudotumoral avascular process. On account of the localisation, the patient being right-handed, no surgical procedure was performed. In spite of corticotherapy and anticonvulsive treatment, seizures recurred and neurological signs slowly progressed. The patient died, 22 months after the first seizure, of an associated disseminated carcinoma with cachexia. Neuropathological examination showed a massive lesion presenting all the features of delayed radionecrosis in the left hemisphere: situated mainly in the white matter; numerous vascular abnormalities; wide-spread demyelination; disappearance of oligoglial cells. The Authors recall the clinical and anatomical aspects of this condition for which the only successful treatment is surgical removal when location and size of the lesion permit. Finally, the mechanisms which have been proposed to explain this delayed cerebral radionecrosis are discussed.

  10. Risk factors for cerebral palsy.

    Science.gov (United States)

    Suvanand, S; Kapoor, S K; Reddaiah, V P; Singh, U; Sundaram, K R

    1997-01-01

    Cerebral palsy is a major cause of crippling in children, but it's etiology is poorly understood. This case control study was done to assess some of the identified risk factors for cerebral palsy, 125 cerebral palsy cases selected from hospital clinic and 125 age and sex matched neighbourhood controls, all aged less than 5 years and residing in Delhi (India) were studied. Information regarding antenatal, natal and postnatal period was collected by mother's interview, and wherever available, from hospital records with the study subjects. Most common type of cerebral palsy was spastic (88%). Quadriplegia was the commonest topographical subtype (86.4%). Birth asphyxia was found to be present in only 25.6% of cases. The commonest risk factor amongst cases was low birth weight (28.8%). The multivariate odds ratios (confidence limits) for the risk factors found to be significantly associated with cerebral palsy were 36.1 (7.76-160) for birth asphyxia, 13.8 (4.95-38.3) for low birth weight, 37.4 (4.47-313) for neonatal convulsion, 23 (4.7-112) for neonatal jaundice, 14.4 (3.69-56.4) for neonatal infection, 24.9 (2.78-223) for instrument assisted delivery and 15.4 (1.57-152) for antepartum hemorrhage. Precipitate labour, caesarean section, twins, toxemia, breech delivery and head injury were not found to be significantly associated with cerebral palsy. Thus birth asphyxia, low birth weight, neonatal convulsions, neonatal jaundice, neonatal infection, instrument assisted delivery and antepartum hemorrhage are significant risk factors for cerebral palsy.

  11. Epidemiologic associations with cerebral palsy.

    Science.gov (United States)

    O'Callaghan, Michael E; MacLennan, Alastair H; Gibson, Catherine S; McMichael, Gai L; Haan, Eric A; Broadbent, Jessica L; Goldwater, Paul N; Dekker, Gustaaf A

    2011-09-01

    To estimate epidemiologic risk factors for cerebral palsy. Data were collected by linkage to state-based perinatal repositories and cerebral palsy registers and using a maternal questionnaire. The cohort included 587 individuals with cerebral palsy and 1,154 non-cerebral palsy controls. The following factors were associated with cerebral palsy: recorded maternal infection during pregnancy (41.4% patients compared with 31.3% controls; odds ratio [OR] 1.55, 95% confidence interval 1.26-1.91), small for gestational age ([birth weight less than third customized centile] 43.9% patients compared with 6.3% controls; OR 11.75, 6.25-22.08), gestational age less than 32 weeks (29.3% patients compared with 0.7% controls; OR 59.20, 28.87-121.38), multiple birth (OR 6.62, 4.00-10.95), a relative with cerebral palsy (OR 1.61, 1.12-2.32), breech position (13.7% patients compared with 6.0% controls; OR 2.48, 1.76-3.49), bleeding at any time in pregnancy (29.3% patients compared with 16.9% controls; OR 2.04, 1.61-2.58), male sex (58.8% patients compared with 45.8% controls; OR 1.68, 1.38-2.06), multiple miscarriage (7.7% patients compared with 3.5% controls; OR 2.30, 1.38-3.82), smoking (14.0% patients compared with 10.6% controls; OR 1.37, 1.02-1.85), and illicit drug use (3.3% patients compared with 1.5% controls; OR 2.22, 1.14-4.30). Factors not associated with cerebral palsy were "disappearing twin," diabetes, maternal body mass index, hypertension, alcohol consumption, anemia, maternal hypothyroidism, forceps or vacuum delivery, and maternal age. Preterm birth, intrauterine growth restriction, perinatal infection, and multiple birth present the largest risks for a cerebral palsy outcome. Reassuringly, upper respiratory tract and gastrointestinal infections during pregnancy were not associated with cerebral palsy. II.

  12. Cerebral Sinovenous Thrombosis

    Directory of Open Access Journals (Sweden)

    Rebecca Ichord

    2017-07-01

    Full Text Available Cerebral sinovenous thrombosis (CSVT is a rare but serious cerebrovascular disorder affecting children from the newborn period through childhood and adolescence. The incidence is estimated at 0.6/100,000/year, with 30–50% occurring in newborns. Causes are diverse and are highly age dependent. Acute systemic illness is the dominant risk factor among newborns. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease. Signs and symptoms are also age related. Seizures and altered mental status are the commonest manifestations in newborns. Headache, vomiting, and lethargy, sometimes with 6th nerve palsy, are the most common symptoms in children and adolescents. Recent multicenter cohort studies from North America and Europe have provided updated information on risk factors, clinical presentations, treatment practices, and outcomes. While systemic anticoagulation is the most common specific treatment used, there are wide variations and many uncertainties even among experts concerning best practice. The treatment dilemma is especially pronounced for neonatal CSVT. This is due in part to the higher prevalence of intracranial hemorrhage among newborns on the one hand, and the clear evidence that newborns suffer greater long-term neurologic morbidity on the other hand. With the advent of widespread availability and acceptance of acute endovascular therapy for arterial ischemic stroke, there is renewed interest in this therapy for children with CSVT. Limited published evidence exists regarding the benefits and risks of these invasive therapies. Therefore, the authors of current guidelines advise reserving this therapy for children with progressive and severe disease who have failed optimal medical management. As research focused on childhood cerebrovascular disease continues to grow rapidly, the future prospects

  13. Octavio Paz y la modernidad: una crítica vanguardista desde los suburbios de la civilización = Octavio Paz and modernity: an avant-gardist criticism from the suburbs of civilization

    Directory of Open Access Journals (Sweden)

    Ledesma, Xavier Rodríguez

    2011-01-01

    Full Text Available Since the fifties of the last century, a Latin American voice began to call attention to the need to think about the meaning of modernity in general and, specifically, how we could give it a new meaning in remote regions, far from the metropolis – and, by doing so and recovering our specificity, find our own ways to reach our own, specific destination. It was the voice of a poet, not of a social scientist or a philosopher. Since few decades, reflection on modernity has become a topic within the academic and cultural world; it is surprising that those deep and avant-gardist digressions are unknown or just denied by the hegemonic centers and discourses of knowledge. The author of this rich, deep, inspiring, avant-gardist and well-written reflection on modernity was the Mexican poet Octavio Paz

  14. 11 Things to Know about Cerebral Palsy

    Science.gov (United States)

    ... Button Past Emails 11 Things to Know about Cerebral Palsy Language: English (US) Español (Spanish) Recommend on Facebook Tweet Share Compartir Cerebral palsy (CP) is the most common motor disability in ...

  15. A reading of latin american avant-garde through the decolonial lense: Alejandro Xul Solar and Joaquín Torres-García, from the ineluctable modern eurocentrism to the search for a communication "other"

    OpenAIRE

    Le Louvier, Kahina Margot

    2015-01-01

    This dissertation revisits modern art in Latin America. The paradoxes of the Latin American avant-garde discourse, which uses modern ideals in order to create a culturally decolonised identity freed from Eurocentrism, are confronted to the theory defended by the decolonial thinking according to which coloniality is inherent to modernity. Through the examination of the texts and paintings of Alejandro Xul Solar and Joaquín Torres-García, two artists who participated in the renew...

  16. NEYROPSYCHOLOGICAL CONSECUENCES OF CEREBRAL PALSY

    Directory of Open Access Journals (Sweden)

    ANA MARÍA NAVARRO MELENDRO

    2005-01-01

    Full Text Available Cerebral Palsy is defined as a movement alteration result of a non progressive damage witch is permanent in anencephalon that has not acquired its final maturation. Patients that suffer cerebral palsy present learning disabilities,that varies between being completely normal to severe as a consequence of memory, gnosis, praxis, perceptive andlanguage impairments. Nevertheless the consequences of this disease are not always predictable. This paper pretendsto make a description of the cognitive and behavioral deficits that overcomes along with the manifestation of thecerebral palsy and its possible treatment. We used a complete neuropsychological battery to evaluate a 7 years oldpatient who was diagnosed of cerebral palsy and spastic diplegia finding some cognitive impairment in fields such asmnesic, gnosic and attention processes.

  17. Cerebral venous thrombosis in childhood

    Energy Technology Data Exchange (ETDEWEB)

    Huisman, T.A.G.M.; Martin, E.; Willi, U.V. [Dept. of Diagnostic Imaging and Radiology, University Children' s Hospital Zurich (Switzerland); Holzmann, D. [Dept. of Otorhinolaryngology, University Children' s Hospital Zurich, Zurich (Switzerland)

    2001-09-01

    This was a retrospective study to determine different etiologies of cerebral venous thrombosis (CVT) in childhood and to correlate extent and location of thrombosis with the etiology and the age of the child as well as the final outcome. In addition, the radiologic approach is discussed. This was a retrospective analysis of 19 children with CVT. The children were examined by contrast-enhanced dynamic CT. Radiologic findings were correlated with the etiology of CVT. Cerebral venous thrombosis is not as infrequent in children as has been thought. Cerebral venous thrombosis in children can occur due to trauma (n=9), infections (n=7), or coagulation disorders (n=3). Extent and location of thrombosis, as well as complications, final outcome, and therapy, depend on the etiology. Computed tomography remains a valuable primary imaging modality in the diagnosis of CVT in the acutely injured or diseased child. (orig.)

  18. Les westerns de John Ford : Du libéralisme d’avant-guerre au conservatisme d’après-guerre

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Esquenazi

    2012-05-01

    Full Text Available L’article propose un moyen de mesurer l’influence sur les cinéastes du milieu dans lequel ils vivent. Sont examinés trois ensembles de westerns de John Ford (réalisés avant guerre, dans l’immédiat après guerre et dans la décennie 1955-1965. Chaque groupe est lié à une situation particulière de l’institution hollywoodienne et de la communauté des cinéastes. L’étude de la mise en scène de scènes récurrentes dans tous ces films révèle des différences pertinentes. Celles-ci peuvent être comprises comme des réactions à l’actualité sociale et politique de Hollywood. The article proposes a way to measure the influence on filmmakers of the environment in which they live. Three wholes of westerns, produced during the pre-war, during the immediate post war and during the decade 1955-1965, are reviewed. Each group is linked to a particular situation of the Hollywood industry. The study of the mise en scene of recurrent scenes in these films reveals relevant differences. These can be understood as reactions to the social and political state of the Hollywood industry.

  19. A DOCUMENTARY STUDY OF AVANTE, THE MAGAZINE OF THE SOCIEDAD GENERAL DE FOTÓGRAFOS DE ESPAÑA (1905-1906

    Directory of Open Access Journals (Sweden)

    Juan Miguel Miguel Sánchez Vigil

    2015-03-01

    Full Text Available The photography magazine Avante, of which there are no copies in the public documentation centers, with the exception of issue number 1 in the library of the Royal Palace, was the official publication of the Sociedad General de Fotógrafos of Spain, an institution which emerged from the first Professional Photographers Assembly held in Madrid in October of 1905. Created and directed by Manuel Compañy, one of the leading authors at the end of the 19th century and beginning of the 20th, only three issues were published, which have not been studied up until now. The object of this study has been to carry out a documentary analysis in order to furnish new data on the photography magazines in Spain and to obtain information to offer researchers on this subject. The results are of great interest in regard to the contents (texts, illustrations and advertising and to the purpose of the magazine in relation with the afore-cited Sociedad General de Fotógrafos.

  20. Effects of Hyperglycemia and Effects of Ketosis on Cerebral Perfusion, Cerebral Water Distribution, and Cerebral Metabolism

    Science.gov (United States)

    Glaser, Nicole; Ngo, Catherine; Anderson, Steven; Yuen, Natalie; Trifu, Alexandra; O’Donnell, Martha

    2012-01-01

    Diabetic ketoacidosis (DKA) may cause brain injuries in children. The mechanisms responsible are difficult to elucidate because DKA involves multiple metabolic derangements. We aimed to determine the independent effects of hyperglycemia and ketosis on cerebral metabolism, blood flow, and water distribution. We used magnetic resonance spectroscopy to measure ratios of cerebral metabolites (ATP to inorganic phosphate [Pi], phosphocreatine [PCr] to Pi, N-acetyl aspartate [NAA] to creatine [Cr], and lactate to Cr) and diffusion-weighted imaging and perfusion-weighted imaging to assess cerebral water distribution (apparent diffusion coefficient [ADC] values) and cerebral blood flow (CBF) in three groups of juvenile rats (hyperglycemic, ketotic, and normal control). ATP-to-Pi ratio was reduced in both hyperglycemic and ketotic rats in comparison with controls. PCr-to-Pi ratio was reduced in the ketotic group, and there was a trend toward reduction in the hyperglycemic group. No significant differences were observed in NAA-to-Cr or lactate-to-Cr ratio. Cortical ADC was reduced in both groups (indicating brain cell swelling). Cortical CBF was also reduced in both groups. We conclude that both hyperglycemia and ketosis independently cause reductions in cerebral high-energy phosphates, CBF, and cortical ADC values. These effects may play a role in the pathophysiology of DKA-related brain injury. PMID:22498698

  1. Cerebral Syphilitic Gumma in Immunocompetent Man, Japan.

    Science.gov (United States)

    Kodama, Tatsuya; Sato, Hidenori; Osa, Morichika; Fujikura, Yuji; Kawana, Akihiko

    2018-02-01

    Although cerebral syphilitic gummas are generally considered to be rare manifestations of tertiary syphilis, many reports exist of early cerebral syphilitic gumma. Our finding of cerebral syphilitic gumma in an HIV-negative man within 5 months after syphilis infection suggests that this condition should be considered in syphilis patients who have neurologic symptoms.

  2. Neuroevolutional Approach to Cerebral Palsy and Speech.

    Science.gov (United States)

    Mysak, Edward D.

    Intended for cerebral palsy specialists, the book emphasizes the contribution that a neuroevolutional approach to therapy can make to habilitation goals of the child with cerebral palsy and applies the basic principles of the Bobath approach to therapy. The first section discusses cerebral palsy as a reflection of disturbed neuro-ontogenisis and…

  3. Cerebral toksoplasmose primaert diagnosticeret som tumor

    DEFF Research Database (Denmark)

    Cortsen, M E; Skøt, J; Skriver, E B

    1992-01-01

    Three cases of cerebral toxoplasmosis as the presenting manifestation of AIDS are reported. The initial diagnoses were brain tumors because of the cerebral mass lesions which resembled glioblastoma. In the light of the increasing occurrence of AIDS, attention is drawn to cerebral toxoplasmosis...

  4. History and definition of delayed cerebral ischemia.

    Science.gov (United States)

    Macdonald, R Loch

    2013-01-01

    A list of the vasospasm meetings is provided. The early descriptions of angiographic vasospasm and delayed cerebral ischemia are presented. Selected advances in knowledge in the field and some controversies are described. A proposal for definitions of neurological deterioration due to delayed cerebral ischemia, of cerebral infarction, and of vasospasm is reviewed.

  5. Features to validate cerebral toxoplasmosis

    Directory of Open Access Journals (Sweden)

    Carolina da Cunha Correia

    2013-06-01

    Full Text Available Introduction Neurotoxoplasmosis (NT sometimes manifests unusual characteristics. Methods We analyzed 85 patients with NT and AIDS according to clinical, cerebrospinal fluid, cranial magnetic resonance, and polymerase chain reaction (PCR characteristics. Results In 8.5%, focal neurological deficits were absent and 16.4% had single cerebral lesions. Increased sensitivity of PCR for Toxoplasma gondii DNA in the central nervous system was associated with pleocytosis and presence of >4 encephalic lesions. Conclusions Patients with NT may present without focal neurological deficit and NT may occur with presence of a single cerebral lesion. Greater numbers of lesions and greater cellularity in cerebrospinal fluid improve the sensitivity of PCR to T gondii.

  6. Lifetime costs of cerebral palsy

    DEFF Research Database (Denmark)

    Kruse, Marie; Michelsen, Susan Ishøy; Flachs, Esben Meulengracht

    2009-01-01

    This study quantified the lifetime costs of cerebral palsy (CP) in a register-based setting. It was the first study outside the US to assess the lifetime costs of CP. The lifetime costs attributable to CP were divided into three categories: health care costs, productivity costs, and social costs....... The population analyzed was retrieved from the Danish Cerebral Palsy Register, which covers the eastern part of the country and has registered about half of the Danish population of individuals with CP since 1950. For this study we analyzed 2367 individuals with CP, who were born in 1930 to 2000 and were alive...

  7. Bounding solutions for cerebral aneurysms

    NARCIS (Netherlands)

    Mikhal, Julia Olegivna; Geurts, Bernardus J.

    2011-01-01

    Cerebral aneurysms are weak spots in the vessel structure of the brain, which present a serious problem to the patient. Julia Mikhal and Bernard Geurts present the application of an Immersed Boundary (IB) method to the simulation of blood flow through such aneurysms. The goal is to understand the

  8. [Intraoperative diagnosis of cerebral gliomas].

    Science.gov (United States)

    Konovalov, A N

    1980-01-01

    At the Burdenko Institute for Neurosurgery in Moscow, the following methods are used for the demarkation of cerebral gliomas: Beta-radiometry, rheometry = measurement of th electrical resistance of the cerebral tissue, staining of the tumour prior to the surgical intervention by means of a Serbinenko catheter, puncture biopsy as well as thermometry. The most frequently used techniques are beta-radiometry and rheometry. The methods are simple in application and the results are reliable. The accuracy of the localisation of a cerebral glioma by means of beta-radiometry is 98 per cent. For the impedance measurement a frequency of 1000 Hz is used. Liquids show the lowest and fibrous meningiomas the highest electrical resistance values. On an average the resistance of cerebral tumours is half as high as that of the average normal brain tissue. In almost all operations one tries to obtain an information about the extent and position of the glioma by means of brain puncture. A special needle probe has been designed to obtain tissue pieces for histological examinations. Experience has also been gained with ultrasonic probing and with temperature measurements of tumour and brain tissue. the interior of the tumours shows a 0.5 to 3 degrees C higher temperature.

  9. MR imaging of cerebral palsy

    Energy Technology Data Exchange (ETDEWEB)

    Saginoya, Toshiyuki [Urasoe General Hospital, Okinawa (Japan); Yamaguchi, Keiichiro; Kuniyoshi, Kazuhide [and others

    1996-06-01

    We evaluated 35 patients with cerebral palsy on the basis of MR imaging findings in the brain. The types of palsy were spastic quadriplegia (n=11), spastic diplegia (n=9), spastic hemiplegia (n=2), double hemiplegia (n=1), athetosis (n=10) and mixed (n=2). Of all patients, 28 (80%) generated abnormal findings. In spastic quadriplegia, although eight cases revealed severe brain damage, two cases showed no abnormal findings in the brain. One of the three had cervical cord compression caused by atlanto-axial subluxation. In spastic diplegia, the findings were divided according to whether the patient was born at term or preterm. If the patient had been born prematurely, the findings showed periventricular leukomalacia and abnormally high intensity in the posterior limbs of the internal capsule on T2-weighted images. MR imaging in spastic hemiplegia revealed cerebral infarction. In the athetoid type, half of all cases showed either no abnormal findings or slight widening of the lateral ventricle. Three cases showed abnormal signals of the basal ganglia. The reason why athetoid-type palsy did not show severe abnormality is unknown. We believe that MR imaging is a useful diagnostic modality to detect damage in the brain in cerebral palsy and plays an important role in the differentiation of cerebral palsy from the spastic palsy disease. (author)

  10. Ocular defects in cerebral palsy

    OpenAIRE

    Katoch Sabita; Devi Anjana; Kulkarni Prajakta

    2007-01-01

    There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP) patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  11. Ocular defects in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Katoch Sabita

    2007-01-01

    Full Text Available There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  12. Ocular defects in cerebral palsy.

    Science.gov (United States)

    Katoch, Sabita; Devi, Anjana; Kulkarni, Prajakta

    2007-01-01

    There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP) patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  13. CT of cerebral hydatid disease

    Energy Technology Data Exchange (ETDEWEB)

    Rudwan, M.A.; Khaffaji, S.

    1988-12-01

    Six cases of cerebral hydatid disease (CHD) were seen in Kuwait over a period of 8 years. The typical CT appearance of a large well-defined spherical nonenhanced unilocular cyst was seen in four cases. Two unusual but characteristic types of calcification were seen, one in each of the remaining two cases.

  14. Cerebral edema in drug addicts

    Directory of Open Access Journals (Sweden)

    Daruši Dragana J.

    2014-01-01

    Full Text Available Background/Aim. The effect of drugs leaves permanent consequences on the brain, organic in type, followed by numerous manifestations, and it significantly affects the development of mental dysfunctions. The clinicians are often given a task to estimate a patient’s personality during treatment or during experts estimate of a drug addict. The aim of this research was to determine the differences, if any, in characteristics of addicts experience and personality traits in drug addicts with or without cerebral edema. Methods. The research was conducted on a sample of 252 male drug addicts, the average age of 23.3 (SD = 4.3 years. Cerebral edema was confirmed on magnetic resonance (MR images of the brain performed during the treatment of the addicts. The participants were tested by the psychologists using Minnesota Multiphasic Personality Inventory (MMPI-201 test, and the data were processed using canonical discriminate analysis within the SPSS program. The dependent variable in the study was cerebral edema. A block of independent variables, designed for the requirements of this study, consisted of two subgroups. The first one consisted of 12 variables describing the relevant characteristics of drug abuse. The second subgroup consisted of 8 psychopathological tendencies in the personality defined by the mentioned test. Results. Cerebral edema was confirmed in 52 (20.63% of the drug addicts. The differences between the groups of drug addicts with and without cerebral edema were determined in the following: the time span of taking drugs (0.301, use of alcohol parallel with drugs (0.466, and treatment for addiction (0.603. In the drug addicts with a cerebral edema, MMPI-201 confirmed the increase in the scales for hypochondria, psychopathic deviations and psychastenia, and the decrease in the scales for schizophrenia and depression. Conclusion. Our study confirmed a possible connection between cerebral edema and personality traits in a number of the

  15. Anestesia e paralisia cerebral Anestesia y parálisis cerebral Anesthesia and cerebral palsy

    Directory of Open Access Journals (Sweden)

    Március Vinícius M Maranhão

    2005-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A paralisia cerebral (PC é uma doença não progressiva decorrente de lesão no sistema nervoso central, levando a um comprometimento motor do paciente. O portador de PC freqüentemente é submetido a procedimentos cirúrgicos devido a doenças usuais e situações particulares decorrentes da paralisia cerebral. Foi objetivo deste artigo revisar aspectos da paralisia cerebral de interesse para o anestesiologista, permitindo um adequado manuseio pré, intra e pós-operatório neste tipo de paciente. CONTEÚDO: O artigo aborda aspectos da paralisia cerebral como etiologia, classificação, fatores de risco, fisiopatologia, quadro clínico, diagnóstico, terapêuticas utilizadas bem como avaliação pré-operatória, medicação pré-anestésica, manuseio intra e pós-operatório, analgesia pós-operatória e dor crônica. CONCLUSÕES: O anestesiologista desempenha um papel importante na diminuição da morbidade e mortalidade anestésico-cirúrgica em pacientes portadores de paralisia cerebral. O conhecimento da fisiopatologia dos diferentes tipos de paralisia cerebral bem como das doenças associadas e suas terapêuticas é imprescindível, pois permite ao anestesiologista antecipar e prevenir complicações intra e pós-operatórias neste tipo de paciente.JUSTIFICATIVA Y OBJETIVOS: La parálisis cerebral (PC es una enfermedad no progresiva consecuente de una lesión en el sistema nervioso central, llevando a un comprometimiento motor del paciente. El portador de PC, frecuentemente es sometido a procedimientos quirúrgicos debido a enfermedades usuales y situaciones particulares consecuentes de la parálisis cerebral. El objetivo de este artículo, fue revisar aspectos de la parálisis cerebral de interés para el anestesista, permitiendo un adecuado manoseo pre, intra y posoperatorio en este tipo de paciente. CONTENIDO: El artículo aborda aspectos de la parálisis cerebral como etiología, clasificación, factores de

  16. Digital subtraction angiography in cerebral infarction

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Sin Young; Kim, Ji Hun; Suh, Hong Kil; Kim, Hyo Heon; Kwack, Eun Young; Lee, Il Seong [College of Medicine Hallym University, Seoul (Korea, Republic of)

    1995-01-15

    The usefulness and radiographic findings of the angiography in cerebral infarction are well known. We attempted to evaluate the angiographic causes, findings, and the usefulness of DSA in cerebral infarction. The authors reviewed retrospectively DSA images of 51 patients who were diagnosed as having cerebral infarction by brain CT and/or MRI and clinical settings. DSA was performed in all 51 patients, and in 3 patients, conventional angiogram was also done. Both carotid DSA images were obtained in AP, lateral, oblique projections, and one or both vertebral DSA images in AP and lateral. The authors reviewed the patient's charts for symptoms, operative findings and final diagnosis, and analysed DSA findings of cerebral atherosclerosis with focus on 6 major cerebral arteries. Among the 51 patients of cerebral infarction 43 patients (84.3%) had cerebral atherosclerosis, 1 dissecting aneurysm, 1 moyamoya disease and 6 negative in angiogram. DSA findings of cerebral atherosclerosis were multiple narrowing in 42 patients (97.7%), tortuosity in 22 (51.2%), dilatation in 14, occlusion in 12, avascular region in 8, collaterals in 7, ulcer in 6, and delayed washout of contrast media in 3. In cerebral atherosclerosis, internal carotid artery was involved in 37 patients (86.0%), middle cerebral artery in 29 (67.4%) posterior cerebral artery in 28, anterior cerebral artery in 26, vertebral artery in 22, and basilar artery in 15. Intracranial involvement of cerebral atherosclerosis (64.9%) was more common than extracranial involvement (16.2%). In cerebral infarction MRA may be the screening test, but for more precise evaluation of vascular abnormality and its extent, DSA should be considered.

  17. Noninvasive measurement of cerebral bioimpedance for detection of cerebral edema in the neonatal piglet.

    Science.gov (United States)

    Lingwood, Barbara E; Dunster, Kimble R; Colditz, Paul B; Ward, Leigh C

    2002-07-26

    The association of sustained cerebral edema with poor neurological outcome following hypoxia-ischaemia in the neonate suggests that measurement of cerebral edema may allow early prediction of outcome in these infants. Direct measurements of cerebral impedance have been widely used in animal studies to monitor cerebral edema, but such invasive measurements are not possible in the human neonate. This study investigated the ability of noninvasive cerebral impedance measurements to detect cerebral edema following hypoxia-ischaemia. One-day-old piglets were anaesthetized, intubated and ventilated. Hypoxia was induced by reducing the inspired oxygen concentration to 4-6% O(2). Noninvasive cerebral bioimpedance was measured using gel electrodes attached to the scalp. Cerebral bioimpedance was also measured directly by insertion of two silver-silver chloride electrodes subdurally. Noninvasive and invasive measurements were made before, during and after hypoxia. Whole body impedance was measured to assess overall fluid movements. Intracranial pressure was measured continuously via a catheter inserted subdurally, as an index of cerebral edema. There was good agreement between noninvasive and invasive measurements of cerebral impedance although externally obtained responses were attenuated. Noninvasive measurements were also well correlated with intracranial pressure. Whole body impedance changes did not account for increases in noninvasively measured cerebral impedance. Results suggest that noninvasive cerebral impedance measurements do reflect intracranial events, and are able to detect cerebral edema following hypoxia-ischaemia in the neonate. Copyright 2002 Elsevier Science B.V.

  18. Endarterectomia e atrofia cortical cerebral

    OpenAIRE

    Luis Eduardo Belini Soares

    2016-01-01

    Resumo: O acidente vascular cerebral isquêmico (AVCi) é uma das principais causas de morte no Brasil e no mundo. Dentre as principais causas destaca-se a doença aterosclerótica, em especial, a formada do bulbo carotídeo. A mesma pode ser considerada sintomática quando é causadora de AVCi ou ataque isquêmico transitório. Todavia, sabe-se que as estenoses ditas assintomáticas, também levam a diminuição de fluxo sanguíneo cerebral. Idosos acima de 80 anos prevalência das estenoses assintomáticas...

  19. Orthostatic Cerebral Hypoperfusion Syndrome (OCHOS

    Directory of Open Access Journals (Sweden)

    Peter eNovak

    2016-02-01

    Full Text Available Objective: Orthostatic dizziness without orthostatic hypotension is common but underlying pathophysiology is poorly understood. This study describes orthostatic cerebral hypoperfusion syndrome (OCHOS. OCHOS is defined by: 1 Abnormal orthostatic drop of cerebral blood flow velocity (CBFv during the tilt test; and 2 Absence of orthostatic hypotension, arrhythmia, vascular abnormalities, or other causes of abnormal orthostatic CBFv.Methods: This retrospective study included patients referred for evaluation of unexplained orthostatic dizziness. Patients underwent standardized autonomic testing including 10 minutes of tilt test. The following signals were monitored: heart rate, end tidal CO2, blood pressure and CBFv from the middle cerebral artery using transcranial Doppler. Patients were screened for OCHOS. Patients which fulfilled the OCHOS criteria were compared to age and gender matched controls.Results: From 1279 screened patients, 102 patients (60/42 women/men, age 51.1±14.9, range 19-84 years fulfilled criteria of OCHOS. There was no difference in baseline supine hemodynamic variables between OCHOS and the control group. During the tilt, mean CBFv decreased 24.1±8.2% in OCHOS versus 4.2±5.6% in controls (p<0.0001 without orthostatic hypotension in both groups. Supine mean blood pressure (OCHOS/controls, 90.5±10.6/91.1±9.4 mmHg, p=0.62 remained unchanged during the tilt (90.4±9.7/92.1±9.6 mmHg, p=0.2. End tidal CO2 and heart rate responses to the tilt were normal and equal in both groups.Conclusion: OCHOS is a novel syndrome of low orthostatic CBFv. Two main pathophysiological mechanisms are proposed including active cerebral vasoconstriction and passive increase of peripheral venous compliance. OCHOS may be a common cause of orthostatic dizziness.

  20. MR findings of cerebral palsy

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sang Hum; Chang, Seung Kuk; Cho, Mee Young; Park, Dong Woo; Kim, Jong Deok; Eun, Choong Ki [Pusan Paik Hospital, Pusan (Korea, Republic of)

    1994-11-15

    To evaluate the MR findings of brain damage in cerebral palised patients and to correlate it with gestational age and the time of damage. A retrospective analysis was performed in 40 patients who underwent MR scanning for evaluation of brain lesion in clinically diagnosed cerebral palsy. Authors classified the patients into two groups as premature and full-term and compared MR findings of the two groups. Abnormal MR findings were noted in 28 cases (70%). Five out of 6 patients who had been born prematurely showed isolate periventricular white matter lesions. Twenty-three out of 34 patients who had been born at full-term showed abnormal MR findings. Of these 23 patients, migration anomalies in 7 patients, isolate periventricular white matter lesions in 3 patients, and other combined periventricular subcortical white matter and deep gray matter lesions in 14 patients were seen. At least, 10 patients(43%) of full term group showed abnormal MRI findings reflecting intrauterine brain damage and all 5 patients of premature group showed isolate periventricular white matter lesions suggesting immaturity of brain. MRI is thought to be very useful in the assessment of brain damage for the patients with cerebral palsy by recognizing the location of the lesion and estimating the time of damage.

  1. Cerebral vasospasm after subarachnoid hemorrhage.

    Science.gov (United States)

    Janjua, Nazli; Mayer, Stephan A

    2003-04-01

    To summarize new pathophysiologic insights and recent advances in the diagnosis and treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Important, newly recognized mediators of cerebral arterial spasm after subarachnoid hemorrhage include superoxide free radicals, ferrous hemoglobin (which acts as a nitric oxide scavenger), endothelins, protein kinase C, and rho kinase. Microvascular dysfunction and autoregulatory failure also has been an area of increasing research focus in recent years. New diagnostic modalities include measures of cerebral blood flow such as single-photon emission computed tomography and perfusion computed tomography, magnetic resonance imaging, intracranial brain oxygen tension probes, and jugular venous oxygen saturation monitors. Proton magnetic resonance spectroscopy and microdialysis can detect tissue biochemical abnormalities, but these techniques have not found their way into routine clinical practice as of yet. In addition to nimodipine and hypertensive hypervolemic therapy, promising new treatments for vasospasm or its ischemic complications include magnesium sulfate, fasudil hydrochloride, tirilazad mesylate, erythropoietin, and induced hypothermia. Balloon angioplasty has emerged as the primary weapon for treating medically refractory ischemia from vasospasm and in many centers is being used as a first-line treatment or even prophylactically. The neurointensive care management of vasospasm after subarachnoid hemorrhage has evolved significantly over the past 10 years, with many new diagnostic modalities and promising treatments now available. Clinical trials are needed to evaluate the efficacy of these new techniques and to further define the optimal management of this often devastating complication. Copyright 2003 Lippincott Williams & Wilkins

  2. Acute hypoxia increases the cerebral metabolic rate

    DEFF Research Database (Denmark)

    Vestergaard, Mark Bitsch; Lindberg, Ulrich; Aachmann-Andersen, Niels Jacob

    2016-01-01

    The aim of the present study was to examine changes in cerebral metabolism by magnetic resonance imaging of healthy subjects during inhalation of 10% O2 hypoxic air. Hypoxic exposure elevates cerebral perfusion, but its effect on energy metabolism has been less investigated. Magnetic resonance...... imaging techniques were used to measure global cerebral blood flow and the venous oxygen saturation in the sagittal sinus. Global cerebral metabolic rate of oxygen was quantified from cerebral blood flow and arteriovenous oxygen saturation difference. Concentrations of lactate, glutamate, N......-acetylaspartate, creatine and phosphocreatine were measured in the visual cortex by magnetic resonance spectroscopy. Twenty-three young healthy males were scanned for 60 min during normoxia, followed by 40 min of breathing hypoxic air. Inhalation of hypoxic air resulted in an increase in cerebral blood flow of 15.5% (p = 0...

  3. Cerebral Edema and Cerebral Hemorrhages in Interleukin-10-Deficient Mice Infected with Plasmodium chabaudi

    OpenAIRE

    Sanni, Latifu A.; Jarra, William; Li, Ching; Langhorne, Jean

    2004-01-01

    During a Plasmodium chabaudi infection in interleukin-10 (IL-10) knockout mice, there is greater parasite sequestration, more severe cerebral edema, and a high frequency of cerebral hemorrhage compared with infection of C57BL/6 mice. Anti-tumor necrosis factor alpha treatment ameliorated both cerebral edema and hemorrhages, suggesting that proinflammatory responses contributed to cerebral complications in infected IL-10−/− mice.

  4. Association of Lead Levels and Cerebral Palsy

    OpenAIRE

    Neha Bansal MD; Anju Aggarwal MD, FIAP, MNAMS; M. M. A. Faridi MD, FIAP, MNAMS; Tusha Sharma PhD; B. D. Baneerjee PhD

    2017-01-01

    Background: Cerebral palsy is a common motor disability in childhood. Raised lead levels affect cognition. Children with cerebral palsy may have raised lead levels, further impairing their residual cognitive motor and behavioral abilities. Environmental exposure and abnormal eating habits may lead to increased lead levels. Aims and Objectives: To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children. To correlate blood lead leve...

  5. Assessment of the hand in cerebral palsy

    OpenAIRE

    Praveen Bhardwaj; S Raja Sabapathy

    2011-01-01

    Cerebral palsy is the musculoskeletal manifestation of a nonprogressive central nervous system lesion that usually occurs due to a perinatal insult to the brain. Though the cerebral insult is static the musculoskeletal pathology is progressive. Some patients with cerebral palsy whose hands are affected can be made better by surgery. The surgical procedures as such are not very technically demanding but the assessment, decision-making, and selecting the procedures for the given patient make th...

  6. Effect of labetalol on cerebral blood flow and middle cerebral arterial flow velocity in healthy volunteers

    DEFF Research Database (Denmark)

    Schroeder, T; Schierbeck, Jens; Howardy, P

    1991-01-01

    The effect of labetalol, a combined alpha- and beta-adrenoceptor antagonist, on the cerebral circulation was investigated in 7 normotensive subjects. Cerebral blood flow (CBF) was measured with the intravenous 133Xe method and mean flow velocity (Vmean) in the middle cerebral artery was determined...

  7. Cerebral Palsy. Fact Sheet = La Paralisis Cerebral. Hojas Informativas Sobre Discapacidades.

    Science.gov (United States)

    National Information Center for Children and Youth with Disabilities, Washington, DC.

    This fact sheet on cerebral palsy is written in both English and Spanish. First, it provides a definition of cerebral palsy and considers various causes (e.g., an insufficient amount of oxygen reaching the fetal or newborn brain). The fact sheet then offers incidence figures and explains characteristics of the three main types of cerebral palsy:…

  8. Cerebral hemodynamics in aging : the interplay between blood pressure, cerebral perfusion, and dementia

    NARCIS (Netherlands)

    Claassen, J.A.H.R.

    2008-01-01

    Advances in measurement techniques have made it possible to study dynamic changes in brain blood flow. Transcranial Doppler ultrasonography measures changes in cerebral blood flow-velocity in the larger cerebral arteries (e.g. the middle cerebral artery). Near infrared spectroscopy records changes

  9. Lipopolysaccharide infusion enhances dynamic cerebral autoregulation without affecting cerebral oxygen vasoreactivity in healthy volunteers

    DEFF Research Database (Denmark)

    Berg, Ronan Mg; Plovsing, Ronni R; Evans, Kevin A

    2013-01-01

    Sepsis may be associated with disturbances in cerebral oxygen transport and cerebral haemodynamic function, thus rendering the brain particularly susceptible to hypoxia. The purpose of this study was to assess the impact of isocapnic hypoxia and hyperoxia on dynamic cerebral autoregulation in a h...... in a human-experimental model of the systemic inflammatory response during the early stages of sepsis....

  10. A study on the pathogenesis of human cerebral malaria and cerebral babesiosis

    Directory of Open Access Journals (Sweden)

    Masamichi Aikawa

    1992-01-01

    Full Text Available Cerebral complications are important, but poorly understood pathological features of infections caused by some species of Plasmodium and Babesia. Patients dying from P. falciparum were classified as cerebral or non-cerebral cases according to the cerebral malaria coma scale. Light microscopy revealed that cerebral microvessels of cerebral malaria patients were field with a mixture of parazited and unparazited erythrocytes, with 94% of the vessels showing parasitized red blood cell (PRBC sequestration. Some degree of PRBC sequestration was also found in non-cerebral malaria patients, but the percentage of microvessls with sequestered PRBC was only 13% Electron microscopy demonstrated knobs on the membrane of PRBC that formed focal junctions with the capillary endothelium. A number of host cell molecules such as CD36, thrombospondim (TSP and intracellular adhesion molecule I (ICAM-1 may function as endothelial cell surfacereports for P. falciparum-infected erythrocytes. Affinity labeling of CD36 and TSP to the PRBC surface showed these molecules specifically bind to the knobs. Babesia bovis infected erythrocytes procedure projections of the erythrocyte membrane that are similar to knobs. When brain tissue from B. bovis-infected cattle was examined, cerebral capillaries were packed with PRBC. Infected erythrocytes formed focal attachments with cerebral endothelial cells at the site of these knob-like projections. These findings indicate that cerebral pathology caused by B. bovis is similar to human cerebral malaria. A search for cytoadherence proteins in the endothelial cells may lead to a better understanding of the pathogenisis of cerebral babesiosis.

  11. Cerebral oxygen metabolism and cerebral blood flow in man during light sleep (stage 2)

    DEFF Research Database (Denmark)

    Madsen, P L; Schmidt, J F; Holm, S

    1991-01-01

    . They differ in respect of arousal threshold as a stronger stimulus is required to awaken a subject from deep sleep as compared to light sleep. Our results suggest that during non-rapid eye movement sleep cerebral metabolism and thereby cerebral synaptic activity is correlated to cerebral readiness rather than...

  12. Blood flow distribution in cerebral arteries.

    Science.gov (United States)

    Zarrinkoob, Laleh; Ambarki, Khalid; Wåhlin, Anders; Birgander, Richard; Eklund, Anders; Malm, Jan

    2015-03-31

    High-resolution phase-contrast magnetic resonance imaging can now assess flow in proximal and distal cerebral arteries. The aim of this study was to describe how total cerebral blood flow (tCBF) is distributed into the vascular tree with regard to age, sex and anatomic variations. Forty-nine healthy young (mean 25 years) and 45 elderly (mean 71 years) individuals were included. Blood flow rate (BFR) in 21 intra- and extracerebral arteries was measured. Total cerebral blood flow was defined as BFR in the internal carotid plus vertebral arteries and mean cerebral perfusion as tCBF/brain volume. Carotid/vertebral distribution was 72%/28% and was not related to age, sex, or brain volume. Total cerebral blood flow (717 ± 123 mL/min) was distributed to each side as follows: middle cerebral artery (MCA), 21%; distal MCA, 6%; anterior cerebral artery (ACA), 12%, distal ACA, 4%; ophthalmic artery, 2%; posterior cerebral artery (PCA), 8%; and 20% to basilar artery. Deviating distributions were observed in subjects with 'fetal' PCA. Blood flow rate in cerebral arteries decreased with increasing age (Psystem.

  13. Late cerebral ischaemia after subarachnoid haemorrhage

    DEFF Research Database (Denmark)

    Edvinsson, L; Povlsen, G K

    2011-01-01

    Late cerebral ischaemia after subarachnoid haemorrhage (SAH) carries high morbidity and mortality because of reduced cerebral blood flow (CBF) and subsequent cerebral ischaemia. This is associated with upregulation of contractile receptors in cerebral artery smooth muscles via the activation...... their sensitivity to endogenous agonists such as ET-1 and 5-HT by increasing their smooth muscle expression of receptors for these after SAH. This is associated with reduced CBF and neurological deficits. A number of signal transduction components mediating this receptor upregulation have been identified, including...

  14. Cerebral Palsy Checklist: Teens & Young Adult (13 to 21)

    Science.gov (United States)

    ... Health Care Decisions Cerebral Palsy Checklist: Teens & Young Adults KidsHealth > For Parents > Cerebral Palsy Checklist: Teens & Young ... plan healthy meals. continue Step 3: Explore Young-Adult Education Young adults with cerebral palsy are entitled ...

  15. Qualit? de vie et v?cu de la maladie, avant et apr?s hyst?rectomie vaginale, chez les femmes admises au Centre Hospitalier Universitaire de Brazzaville

    OpenAIRE

    Mbongo, Jean Alfred; Mouanga, Alain; Miabaou, Didace Massamba; Nzelie, Aya; Iloki, L?on Herv?

    2016-01-01

    Toute maladie est un mal en soi qu?il faut ?radiquer car elle alt?re souvent de fa?on significative la qualit? de la vie. L?hyst?rectomie vaginale est indiqu?e pour les patientes qui pr?sentent certaines affections gyn?cologiques graves, elle est donc b?n?fique mais, peut ?galement avoir une r?percussion n?faste sur la qualit? de vie de la femme. Ainsi nous avons voulu explorer le v?cu de la maladie et de l?hyst?rectomie vaginale (HV) des femmes avant et apr?s l?intervention chirurgicale. Nou...

  16. Est-il encore justifié et éthique de réaliser un bilan urodynamique avant la chirurgie de l’incontinence d’effort de la femme ?

    OpenAIRE

    Fritel, Xavier

    2015-01-01

    International audience; De nombreux chirurgiens ont l’habitude de demander un bilan urodynamique avant de réaliser une chirurgie de l’incontinence urinaire de la femme en particulier en cas d’incontinence mixte. Cet usage est conforme aux recommandations des sociétés savantes françaises (Collège National des Gynécologues et Obstétriciens Français et Association Française d’Urologie) publiées en 2010...

  17. Esporte e vanguardas artísticas: cubismo, Ashcan School e expressionismo Sport and avant-garde art: cubism, the Aschan School and expressionism

    Directory of Open Access Journals (Sweden)

    Victor Andrade de Melo

    2011-03-01

    Full Text Available Considerando que os movimentos artísticos possuem algum grau de coerência interna no que se refere a uma forma peculiar de estabelecer relação com o contexto histórico e com o próprio fazer artístico, esse estudo teve por objetivo discutir a presença do esporte em obras de arte ligadas ao cubismo, à Ashcan School e ao expressionismo. Para alcance do objetivo, trabalhando com a ideia de que é possível construir uma historia cultural/antropologia histórica da imagem (BURKE, 2004, adotou-se o modelo de análise e interpretação de Melo (2009. Cremos ser possível lançar olhares sobre o esporte a partir de sua inserção na construção do imaginário moderno, bem como o oposto: prospectar a modernidade desde a prática esportiva. Ao final concluiu-se que o quadro multifacetado de aproximação dessas vanguardas com o esporte nos ajuda a ter uma noção de como a manifestação estava se configurando e compondo seu quadro de popularização.Considering that the art movements have a certain degree of inner coherence regarding a peculiar form of establishing a connection between the historical context and the art making itself, this study aims at discussing the presence of sport in works of art related to cubism, the Aschan School and to expressionism. In order to reach that goal, working with the idea that it is possible to make a cultural/anthropological history of image (BURKE, 2004, we have adopted Melo's (2009 model of analysis and interpretation. We believe it is possible to cast new visions about sport from its insertion in the making of the modern imaginary, as well as the opposite: to prospect modernity itself from the sport practice. At the end we have concluded that the multifaceted picture of the approximation of those avant-gardes with sport might help us understand how the manifestation was being shaped, within their popularization set up.

  18. Models of Cerebral-Body Perfusion and Cerebral Chemical Transport.

    Science.gov (United States)

    1988-03-01

    Compartmental modelling, perfusion flux and pressure, interaction between cerebral, respiratory and heart syz 19. TRACT (Continue on reverse if niecesmay and...ZFB and -CB (0 < (18) Zp 3l where a (- 10000) Indicates the ratio of the vein-venous sinous to the cerebrospinal fluid-brain barrier, and 03( = 1...mean venous sinous efflux. Is given by Q, = Q; a Q" = 750m.mlin. Because Q, Q; and Q; are a-priori known, and the mean head values h cC . hlp, h;,A

  19. Cerebral oxygen metabolism and cerebral blood flow in man during light sleep (stage 2)

    DEFF Research Database (Denmark)

    Madsen, P L; Schmidt, J F; Holm, S

    1991-01-01

    We measured cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) during light sleep (stage 2) in 8 young healthy volunteers using the Kety-Schmidt technique with 133Xe as the inert gas. Measurements were performed during wakefulness and light sleep as verified by standard....... They differ in respect of arousal threshold as a stronger stimulus is required to awaken a subject from deep sleep as compared to light sleep. Our results suggest that during non-rapid eye movement sleep cerebral metabolism and thereby cerebral synaptic activity is correlated to cerebral readiness rather than...

  20. Multiple cerebral aneurysms of middle cerebral artery. Case report

    Directory of Open Access Journals (Sweden)

    D.A. Nica1, Tatiana Rosca1, A. Dinca2, M. Stroi3, Mirela Renta4, A.V. Ciurea5

    2010-11-01

    Full Text Available Multiple cerebral aneurysms present awide variation in incidence with averages of13% at angiographic studies and 22.7% atautopsy.High blood pressue, cigarette smoking,stress and possible also age and female sexseem to be risk factors for multipleintracranial aneurysms (MIAn in patientsof working age who have suffered asubarachnoid hemorrhage (SAH.Aneurysms were situated on the same sidein one-third of the patients with twoaneurysms and the most common site wasthe middle cerebral artery (MCA. Tomanage these challenging lesionsneurosurgeons must use all availableinnovations and advances, includingdiagnostic, technical and perioperativeadjuncts. The author presents a case ofmiddle age female, with two saccularaneurysms situated on the same side (rightMCA, who was operated in our clinic, 20days after first SAH episode, I grade onHunt/Hess scale. The angio MRI wasperformed before, and control DSangiography after operation. After pterionalapproach, the author used themagnification, microsurgical technics,temporal clip, and two permanent Yasargilcurved clips. A postoperative good recoveryenable the patient go to work and drive onemonth later.

  1. Cerebral oximetry in preterm infants

    DEFF Research Database (Denmark)

    Greisen, Gorm; Andresen, Bjørn; Plomgaard, Anne Mette

    2016-01-01

    Preterm birth constitutes a major cause of death before 5 years of age and it is a major cause of neurodevelopmental impairment across the world. Preterm infants are most unstable during the transition between fetal and newborn life during the first days of life and most brain damage occurs...... in this period. The brain of the preterm infant is accessible for tissue oximetry by near-infrared spectroscopy. Cerebral oximetry has the potential to improve the long-term outcome by helping to tailor the support of respiration and circulation to the individual infant's needs, but the evidence is still lacking...

  2. Flow structures in cerebral aneurysms

    OpenAIRE

    Gambaruto, Alberto M; João, Ana

    2012-01-01

    Mechanical properties of blood flow are commonly correlated to a wide range of cardiovascular diseases. In this work means to describe and characterise the flow field in the free-slip and no-slip domains are discussed in the context of cerebral aneurysms, reconstructed from in-vivo medical imaging. The approaches rely on a Taylor series expansion of the velocity field to first order terms that leads to a system of ODEs, the solution to which locally describes the motion of the flow. On perfor...

  3. Visual disorders in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Govind Amita

    1988-01-01

    Full Text Available Seventy children with cere-bral palsy were examined for aetiological factors responsible, type of disorder and ocular abnormalities. The overall inci-dence of ocular abnormalities was 68.69%, the highest frequency being of squint (35.7%. Other anomalies detected inclu-ded refractive errors (28.5%, optic atrophy (10% and coloboma (2.9%. Most children were spastic quadriplegics with asphyxia as the major aetiological factor. The study created an awareness amongst parents of these children. The visual status of those affected could be improved for imparting education and training in a better way.

  4. Nonsulfated cholecystokinins in cerebral neurons

    DEFF Research Database (Denmark)

    Agersnap, Mikkel; Zhang, Ming-Dong; Harkany, Tibor

    2016-01-01

    Cholecystokinin (CCK) is a widely expressed neuropeptide system originally discovered in the gut. Both cerebral and peripheral neurons as well as endocrine I-cells in the small intestine process proCCK to tyrosyl-O-sulfated and α-carboxyamidated peptides. Recently, we reported that gut endocrine I...... for nonsulfated CCK-8 with an antibody recognizing both sulfated and nonsulfated CCK. However, nonsulfated CCK immunoreactivity was stronger than that of sulfated CCK in cell bodies and weaker in nerve terminals. We conclude that only a small fraction of neuronal CCK is nonsulfated. The intracellular distribution...... of nonsulfated CCK in neurons suggests that they contribute only modestly to the CCK transmitter activity....

  5. Animal models of cerebral arterial gas embolism

    NARCIS (Netherlands)

    Weenink, Robert P.; Hollmann, Markus W.; van Hulst, Robert A.

    2012-01-01

    Cerebral arterial gas embolism is a dreaded complication of diving and invasive medical procedures. Many different animal models have been used in research on cerebral arterial gas embolism. This review provides an overview of the most important characteristics of these animal models. The properties

  6. Ataxic cerebral palsy and genetic predisposition.

    OpenAIRE

    Miller, G.

    1988-01-01

    It was calculated that in the 962 family members of 36 patients with ataxic cerebral palsy there were 75 (8%) with a history of neurodevelopmental disorder and 31 (3%) with a major congenital malformation. This was not significantly greater than expected, and does not support the hypothesis of a genetic non-Mendelian role in the aetiology of ataxic cerebral palsy.

  7. Cerebral emboli and depressive symptoms in dementia.

    NARCIS (Netherlands)

    Purandare, N.; Oude Voshaar, R.C.; Hardicre, J.; Byrne, J.; McCollum, C.N.; Burns, A.

    2006-01-01

    BACKGROUND: The vascular depression hypothesis and our recent findings of increased frequency of spontaneous cerebral emboli in dementia suggest that such emboli may be involved in the causation of depressive symptoms in dementia. AIMS: To evaluate the association between spontaneous cerebral emboli

  8. Spontaneous peripheral gangrene following severe cerebral malaria

    African Journals Online (AJOL)

    ... phalanges of the right index and middle fingers and the distal phalanges of the great, second and middle toes of the right foot following cerebral malaria. Until now, there has been only five such cases of peripheral gangrene associated with 'cerebral' malaria reported in literature and all these were all from Southeast Asia.

  9. Fatal cerebral oedema in adult diabetic ketoacidosis.

    NARCIS (Netherlands)

    Haringhuizen, A.; Tjan, D.H.; Grool, A.; Vugt, R. van; Zante, A.R. van

    2010-01-01

    In this report, a case of adult onset fatal cerebral oedema as a rare complication of diabetic ketoacidosis (DKA) is described and confirmed at post-mortem pathological examination. The pathogenesis of cerebral oedema due to DKA is still unknown. Potential mechanisms include the administration of

  10. Hereditary cerebral small vessel disease and stroke

    DEFF Research Database (Denmark)

    Søndergaard, Christian Baastrup; Nielsen, Jørgen Erik; Hansen, Christine Krarup

    2017-01-01

    Cerebral small vessel disease is considered hereditary in about 5% of patients and is characterized by lacunar infarcts and white matter hyperintensities on MRI. Several monogenic hereditary diseases causing cerebral small vessel disease and stroke have been identified. The purpose of this system...

  11. Cerebral blood flow response to functional activation

    DEFF Research Database (Denmark)

    Paulson, Olaf B; Hasselbalch, Steen G; Rostrup, Egill

    2010-01-01

    Cerebral blood flow (CBF) and cerebral metabolic rate are normally coupled, that is an increase in metabolic demand will lead to an increase in flow. However, during functional activation, CBF and glucose metabolism remain coupled as they increase in proportion, whereas oxygen metabolism only...

  12. OCULAR FINDINGS IN CHILDREN WITH CEREBRAL PALSY ...

    African Journals Online (AJOL)

    Cerebral palsy is commonly associated with ocular abnormalities which often impact on their development and education. There is paucity of studies on this in Nigeria. We decided to study/ determine the prevalence of ocular abnormalities among children with cerebral palsy that attended the neurology clinic of University of ...

  13. Mobility Experiences of Adolescents with Cerebral Palsy

    Science.gov (United States)

    Palisano, Robert J.; Shimmell, Lorie J.; Stewart, Debra; Lawless, John J.; Rosenbaum, Peter L.; Russell, Dianne J.

    2009-01-01

    The purpose of this study was to describe how youth with cerebral palsy experience mobility in their daily lives using a phenomenological approach. The participants were 10 youth with cerebral palsy, 17 to 20 years of age, selected using purposeful sampling with maximum variation strategies. A total of 14 interviews were completed. Transcripts…

  14. Middle cerebral artery blood velocity during running

    NARCIS (Netherlands)

    Lyngeraa, T. S.; Pedersen, L. M.; Mantoni, T.; Belhage, B.; Rasmussen, L. S.; van Lieshout, J. J.; Pott, F. C.

    2013-01-01

    Running induces characteristic fluctuations in blood pressure (BP) of unknown consequence for organ blood flow. We hypothesized that running-induced BP oscillations are transferred to the cerebral vasculature. In 15 healthy volunteers, transcranial Doppler-determined middle cerebral artery (MCA)

  15. Avant et après de Paul Gauguin : un autoportrait - récit revendicatif d’une vie, récit paradisiaque d’une enfance

    Directory of Open Access Journals (Sweden)

    Béatrice Vernier-Larochette

    2010-05-01

    Full Text Available Si l’écriture autobiographique a bien souvent comme point de départ l’enfance, il n’en est pas ainsi dans l’ouvrage Avant et après que Gauguin décide d’écrire peu avant sa mort, où il n’évoque son enfance que dans la seconde moitié du livre. Par ailleurs, l’envie de se raconter le plus rigoureusement possible est corrigée dans ce recueil par une expression ludique qui rappelle au lecteur qu’il ne s’agit que de “notes éparses, sans suite.” Ces contradictions que nous dégageons dans cet article nous permettent, d’après notre analyse, de rattacher cette écriture à celle d’un autoportrait tel que l’envisage Michel Beaujour dans son ouvrage Miroir d’encre. Rhétorique de l’autoportrait.

  16. CT findings in patients with cerebral palsy

    Energy Technology Data Exchange (ETDEWEB)

    Konno, K. (Akita Univ. (Japan))

    1982-01-01

    Clinical findings and CT findings in 73 cases of cerebral palsy were studied. The causes of cerebral palsy were presumed to be as follows: abnormal cerebral development (36%), asphyxial delivery (34%), and immature delivery (19%), etc. CT findings were abnormal in 58% of the 73 cases, 83% of the spastic tetraplegia patients and all of the spastic hemiplegia patients showed abnormal CT findings. All the patients with spastic monoplegia presented normal CT findings. In 75% of the spastic hemiplegia cases, the CT abnormalities were due to cerebral parenchymal abnormality such as porencephaly and regional low absorption. In cases of spastic tetraplegia, cerebral parenchymal abnormality was found only in 10%. Cortical atrophy was found only in 15 of the 73 cases, whereas central atrophy was found in 36 cases.

  17. Cerebral astrocytoma in a sheep

    Science.gov (United States)

    Farjanikish, Ghasem; Khodakaram-Tafti, Azizollah; Dezfoulian, Omid

    2017-01-01

    Astrocytoma as one of the most common central nervous system (CNS) tumors is rarely reported in veterinary literature. A 7-year-old Persian Lori-Bakhtiari ewe was presented to the clinic with a two months history of progressive blindness, nystagmus to the right, bilaterally decreased pupillary reflexes, head pressing and paddling. At necropsy, a whitish well-circumscribed mass with dimensions of 3.50×2.50×1.50 cm was observed in the dorsal parietal lobe of the left cerebral hemisphere. Microscopically, the mass was well-circumscribed and highly cellular, consisted of round to elongated cells with scant and vacuolated cytoplasm with few, flaccid processes. The nuclei were round to oval with densely stippled chromatin and indistinct nucleoli. Immunohistochemical analyses showed positive staining for vimentin, S100 and glial fibrillary acidic protein. Definitive diagnosis of cerebral protoplasmic astrocytoma was made on the basis of the histopathological and immunohistochemical findings. This type of neoplasm should be included in the differential diagnosis of CNS lesions in the sheep. PMID:29085617

  18. Neuroimaging patterns of cerebral hyperperfusion

    Science.gov (United States)

    Semenov, S.; Portnov, Yu; Semenov, A.; Korotkevich, A.; Kokov, A.

    2017-08-01

    Cerebral hyperperfusion syndrome (CHS) after revascularization is a rare phenomenon associated with post-ischemic (reactive) hyperemia and acute pathological hyperperfusion. First described on perfusion CT as a very often moderate CBF increase, MTT/TTP decrease within 30% like a temporary effect, according to a short-time deterioration of neurological symptoms (vestibular ataxia - 58%, vegetative dysfunction - 100%, asthenic syndrome - 100%) in early postoperative period in patients with cardiac ischemia who had undergone coronary artery bypass surgery. The acute pathological hyperperfusion carotid revascularization is a casuistic phenomenon with two- or three-fold CBV and MTT/TTP increase and high hemorrhage risk. Besides, we detected similar exchanges via perfusion CT called benign hyperemia, which marks extension of MTT/TTP and an increase of CBV from 27% to 48% (average 30%), but with normal CBF-parameters, indicating that venous stasis in acute venous ischemic stroke due cerebral venous sinus-trombosis (68%), only 6% in cardioembolic stroke and appears never in arterial stroke. Territorial coincidence registered for perifocal of necrosis zones of benign hyperemia and vasogenic edema accompanied on MRI (DWI, ADC). Secondary hemorrhagic transformation registered for primary non-hemorrhagic venous stroke in 27%, only in 9% for arterial stroke and in 60% for cardioembolic stroke. Probably, congestion is an increasingly predisposing factor secondary hemorrhaging than necrosis.

  19. A lumped parameter model of cerebral blood flow control combining cerebral autoregulation and neurovascular coupling.

    Science.gov (United States)

    Spronck, Bart; Martens, Esther G H J; Gommer, Erik D; van de Vosse, Frans N

    2012-11-01

    Cerebral blood flow regulation is based on a variety of different mechanisms, of which the relative regulatory role remains largely unknown. The cerebral regulatory system expresses two regulatory properties: cerebral autoregulation and neurovascular coupling. Since partly the same mechanisms play a role in cerebral autoregulation and neurovascular coupling, this study aimed to develop a physiologically based mathematical model of cerebral blood flow regulation combining these properties. A lumped parameter model of the P2 segment of the posterior cerebral artery and its distal vessels was constructed. Blood flow regulation is exerted at the arteriolar level by vascular smooth muscle and implements myogenic, shear stress based, neurogenic, and metabolic mechanisms. In eight healthy subjects, cerebral autoregulation and neurovascular coupling were challenged by squat-stand maneuvers and visual stimulation using a checkerboard pattern, respectively. Cerebral blood flow velocity was measured using transcranial Doppler, whereas blood pressure was measured by finger volume clamping. In seven subjects, the model proposed fits autoregulation and neurovascular coupling measurement data well. Myogenic regulation is found to dominate the autoregulatory response. Neurogenic regulation, although only implemented as a first-order mechanism, describes neurovascular coupling responses to a great extent. It is concluded that our single, integrated model of cerebral blood flow control may be used to identify the main mechanisms affecting cerebral blood flow regulation in individual subjects.

  20. L’aménagement du territoire avant la lettre : quelques exemples genevois (XVIIIe-XIXe siècles

    Directory of Open Access Journals (Sweden)

    Isabelle Roland

    2012-04-01

    Full Text Available Les facteurs historiques et géopolitiques ont eu, à Genève, une influence notable sur la structure du territoire et la morphologie de certaines localités. A Meyrin par exemple, la création d’un nouvel axe routier a transformé en quelques années un village-rue en village-carrefour. A Malagny, un hameau d’origine médiévale a été presque entièrement détruit au XVIIIe siècle pour faire place à un grand domaine. A Genthod, un modeste village s’est embourgeoisé suite à l’implantation de trois domaines patriciens et les paysans ont accepté de déplacer leur fumier dans une rue secondaire, créée à cet effet. A Chêne, un village a été scindé en deux entités politiques et confessionnelles bien distinctes, tandis qu’à Plan-les-Ouates, le contraste est frappant entre les deux côtés de la rue principale, colonisés à deux époques différentes. Ces quelques exemples relèvent de ce que l’on peut considérer comme de l’aménagement du territoire avant la lettre et démontrent qu’il est impossible de dissocier l’architecture rurale de son environnement et de son histoire.In Geneva, historic and geopolitical factors have significantly influenced the region’s overall structure and the form of particular locals within it. For example, in the course of just a few years, a new road transformed Meyrin from a one-street village into an important commercial crossroad. In Malagny, a medieval hamlet was almost entirely demolished in the 18th century to make way for a grand estate. In Genthod, a farming village was “gentrified” after 3 nobles estates were established around it. The village peasants agreed to move their dung-heaps to a more discreet secondary street, donated by one of the estates for the purpose. In Chêne, a village was divided into two distinct political and religious districts. Finally, at Plan-les-Ouates, there is a strong contrast between the two sides of the village’s main street, which were

  1. ocular findings in children with cerebral palsy attending a tertiary ...

    African Journals Online (AJOL)

    diplegia and spastic tetraplegia types. Beckung,. Hagberg and Uldall (2008: e187-92) classified them as Spastic unilateral cerebral palsy, Spastic bilateral cerebral palsy and dyskinetic cerebral palsy and ataxic cerebral palsy. In the spastic type there is stiffness and movement difficulties, in ataxic form there is a disturbance ...

  2. Cerebral Lactate Metabolism After Traumatic Brain Injury.

    Science.gov (United States)

    Patet, Camille; Suys, Tamarah; Carteron, Laurent; Oddo, Mauro

    2016-04-01

    Cerebral energy dysfunction has emerged as an important determinant of prognosis following traumatic brain injury (TBI). A number of studies using cerebral microdialysis, positron emission tomography, and jugular bulb oximetry to explore cerebral metabolism in patients with TBI have demonstrated a critical decrease in the availability of the main energy substrate of brain cells (i.e., glucose). Energy dysfunction induces adaptations of cerebral metabolism that include the utilization of alternative energy resources that the brain constitutively has, such as lactate. Two decades of experimental and human investigations have convincingly shown that lactate stands as a major actor of cerebral metabolism. Glutamate-induced activation of glycolysis stimulates lactate production from glucose in astrocytes, with subsequent lactate transfer to neurons (astrocyte-neuron lactate shuttle). Lactate is not only used as an extra energy substrate but also acts as a signaling molecule and regulator of systemic and brain glucose use in the cerebral circulation. In animal models of brain injury (e.g., TBI, stroke), supplementation with exogenous lactate exerts significant neuroprotection. Here, we summarize the main clinical studies showing the pivotal role of lactate and cerebral lactate metabolism after TBI. We also review pilot interventional studies that examined exogenous lactate supplementation in patients with TBI and found hypertonic lactate infusions had several beneficial properties on the injured brain, including decrease of brain edema, improvement of neuroenergetics via a "cerebral glucose-sparing effect," and increase of cerebral blood flow. Hypertonic lactate represents a promising area of therapeutic investigation; however, larger studies are needed to further examine mechanisms of action and impact on outcome.

  3. Cerebral hypoxic ischemia at different cerebral oxygen saturations in piglets: amplitude-integrated EEG study.

    Science.gov (United States)

    Zhang, Dandan; Ding, Haiyan; Hou, Xinlin; Liu, Yunfeng; Ye, Datian

    2008-01-01

    the objective of present paper was to study the amplitude-integrated EEG (aEEG) in hypoxic ischemic (HI) animal models and to test the reliability of aEEG method when used to monitor cerebral injuries. HI animal models were constructed and classified into mild, moderate and severe cerebral oxygen saturation groups according to regional oxygen saturation (rSO(2)) in brains. Then aEEG waveforms were obtained from raw EEG data using digital signal processing. aEEG reflected cerebral functions consistently and accurately at different cerebral rSO(2) levels. aEEG waveforms rarely changed in the group of mild HI; they dropped but recovered in moderate HI group; and aEEG maintained very low after HI in the cases when severe HI happened. aEEG method could monitor cerebral functions directly, accurately and consistently. It is a reliable tool to continuously evaluate cerebral injuries.

  4. Atypical radiological findings in cerebral hydatid disease.

    Science.gov (United States)

    Benzagmout, Mohammed; Maaroufi, Mustapha; Chakour, Khalid; Chaoui, Mohammed E

    2011-07-01

    Cerebral hydatid disease is very rare, representing only 2% of all cerebral space occupying lesions. The diagnosis is usually based on a pathognomonic CT pattern. Exceptionally, the image is atypical raising suspicion of many differential diagnoses such as intracerebral infectious, vascular lesions, or tumors. We report 2 atypical cases of cerebral hydatid cysts diagnosed in a 21, and a 24-year-old woman. The CT scan results suggest oligodendroglioma in the first case and brain abscess in the second. An MRI was helpful in the diagnosis of the 2 cases. Both patients underwent successful surgery with a good outcome. The hydatid nature of the cyst was confirmed by histology in both cases.

  5. The serpentine mitral valve and cerebral embolism

    Directory of Open Access Journals (Sweden)

    Ker James

    2011-02-01

    Full Text Available Abstract Valvular strands, well-delineated filiform masses, attached to cardiac valve edges are associated with cerebral embolism and stroke. Strokes, caused by emboli from valvular strands, tend to occur among younger persons. In this case report a valvular strand, giving a peculiar serpentine appearance to the mitral valve is described. This mitral valvular strand was the only explanation for an episode of cerebral embolism, presenting with a transient right sided hemiparesis. It is proposed that a randomized study involving combined treatment with aspirin and clopidogrel is warranted in young patients with valvular strands, presenting with a first episode of cerebral embolism.

  6. [Cerebral artery thrombosis in pregnancy].

    Science.gov (United States)

    Charco Roca, L M; Ortiz Sanchez, V E; Hernandez Gutierrez-Manchon, O; Quesada Villar, J; Bonmatí García, L; Rubio Postigo, G

    2015-11-01

    A 28 year old woman, ASA I, who, in the final stages of her pregnancy presented with signs of neural deficit that consisted of distortion of the oral commissure, dysphagia, dysarthria, and weakness on the left side of the body. She was diagnosed with thrombosis in a segment of the right middle cerebral artery which led to an ischemic area in the right frontal lobe. Termination of pregnancy and conservative treatment was decided, with good resolution of the symptoms. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  7. Cerebral hyperperfusion following carotid endarterectomy

    DEFF Research Database (Denmark)

    Schroeder, T; Sillesen, H; Sørensen, O

    1987-01-01

    Serial measurements of cerebral blood flow (CBF) were performed in 56 patients before and one to four times after uncomplicated carotid endarterectomy. The findings were related to the ratio between internal carotid artery (ICA) and common carotid artery (CCA) mean pressures. Within the 1st...... postoperative day CBF increased by a median of 37% in the ipsilateral and 33% in the contralateral hemisphere. Later recordings showed a gradual return of CBF toward the preoperative level. Sixteen patients with an ICA/CCA pressure ratio below 0.7 showed a significantly more pronounced and longer-lasting flow......, occurred in the low pressure ratio group, while the hemispheric asymmetry on average was unchanged in the high pressure ratio group. This relative hyperemia was most pronounced 2 to 4 days following reconstruction. The marked hyperemia, absolute as well as relative, in patients with a low ICA/CCA pressure...

  8. Enhanced contractility of intraparenchymal arterioles after global cerebral ischemia in rat - new insights into the development of delayed cerebral hypoperfusion

    DEFF Research Database (Denmark)

    Spray, Stine; Johansson, Sara Ellinor; Radziwon-Balicka, Aneta

    2017-01-01

    in the large arteries on the brain surface (pial arteries) after global cerebral ischemia. However, smaller arterioles inside the brain (parenchymal arterioles) are equally important in the regulation of cerebral blood flow and yet their pathophysiology after global cerebral ischemia is largely unknown...... of delayed cerebral hypoperfusion after global cerebral ischemia in combination with vascular changes of the pial vasculature. This article is protected by copyright. All rights reserved....

  9. Cerebral schistosomiasis | Ravi | SA Journal of Radiology

    African Journals Online (AJOL)

    Although schistosomiasis (bilharzia) is one of the most common parasitic infections in humans, schistosomal infection of the nervous system is rare. This report is of an unusual case of primary cerebral schistosomiasis and describes its magnetic resonance imaging appearance.

  10. Middle cerebral artery blood velocity during running

    DEFF Research Database (Denmark)

    Lyngeraa, Tobias; Pedersen, Lars Møller; Mantoni, T

    2013-01-01

    Running induces characteristic fluctuations in blood pressure (BP) of unknown consequence for organ blood flow. We hypothesized that running-induced BP oscillations are transferred to the cerebral vasculature. In 15 healthy volunteers, transcranial Doppler-determined middle cerebral artery (MCA......) blood flow velocity, photoplethysmographic finger BP, and step frequency were measured continuously during three consecutive 5-min intervals of treadmill running at increasing running intensities. Data were analysed in the time and frequency domains. BP data for seven subjects and MCA velocity data....... During running, rhythmic oscillations in arterial BP induced by interference between HR and step frequency impact on cerebral blood velocity. For the exercise as a whole, average MCA velocity becomes elevated. These results suggest that running not only induces an increase in regional cerebral blood flow...

  11. INTEGRATED REHABILITATION APPROACH IN CEREBRAL PALSY PATIENTS

    National Research Council Canada - National Science Library

    Bellomo, R.G; Barassi, G; Verì, N; Giannuzzo, G; Di Felice, P; Pecoraro, I; D’Ettole, S; Saggini, R

    2017-01-01

    Introduction: cerebral palsy (CP) is a condition determined by a damage occurred in the developing brain of children during the first year of life, resulting in cognitive alterations and motor disorders like spasticity...

  12. Cerebral cysticercosis in a cat : clinical communication

    Directory of Open Access Journals (Sweden)

    E.V. Schwan

    2002-07-01

    Full Text Available The metacestode of Taenia solium, Cysticercus cellulosae, was recovered from the brain of a cat showing central nervous clinical signs ante mortem. This is the first record of cerebral cysticercosis in a cat in South Africa.

  13. Resonancia magnetica cerebral: secuencias basicas e interpretacion

    National Research Council Canada - National Science Library

    Caballero, Ligia; Puentes, Sofia; Rivera, Diego Miguel

    2011-01-01

    La resonancia magnetica cerebral se ha establecido como una herramienta muy valiosa para el diagnostico de enfermedades neurologicas, debido a su capacidad de proveer excelente detalle y caracterizacion de los tejidos...

  14. Cerebral cavernous malformation proteins at a glance

    National Research Council Canada - National Science Library

    Draheim, Kyle M; Fisher, Oriana S; Boggon, Titus J; Calderwood, David A

    2014-01-01

    ...) cause cerebral cavernous malformations (CCMs). These abnormalities are characterized by dilated leaky blood vessels, especially in the neurovasculature, that result in increased risk of stroke, focal neurological defects and seizures...

  15. Cerebral Amyloid Angiopathy: A Systematic Review

    National Research Council Canada - National Science Library

    Biffi, Alessandro; Greenberg, Steven M

    2011-01-01

    Cerebral amyloid angiopathy (CAA) is a disorder characterized by amyloid deposition in the walls of leptomeningeal and cortical arteries, arterioles, and less often capillaries and veins of the central nervous system...

  16. Postishemic Cerebral Function and Blood Flow

    Directory of Open Access Journals (Sweden)

    V. V. Aleksandrin

    2005-01-01

    Full Text Available The impact of massive blood loss on cerebral blood flow-function relationships was studied in rats in the postis-chemic period. Anxiety was examined in the raised cross-shaped labyrinth. Cerebral blood flow was registered by a laser Doppler flowmeter. One-hour massive blood flow substantially increased the level of anxiety in 75% of the rats following 7 and 20 days. There were no significant behavior changes in 25% of the animals. Experimental animals with preserved behavioral parameters showed cerebral blood flow resistance to ischemia and reperfusion while rats with increased anxiety were found to have delayed postischemic hypoperfusion. Thus, a relationship was found between the behavior of the rats and the resistance of cerebral blood flow to ischemia and reperfusion.

  17. Transcranial cerebral oximetry in random normal subjects

    Science.gov (United States)

    Misra, Mukesh; Stark, Jennifer; Dujovny, Manuel; Alp, M. Serdar; Widman, Ronald; Ausman, James I.

    1997-08-01

    Near infrared optical spectroscopy is becoming a useful method for monitoring regional cerebral oxygenation status. The method is simple, reliable and noninvasive and the information which it provides is clinically significant in managing a growing number of neurological ailments. Use of this technique has been described previously by numerous authors. In the present study, regional cerebral oxygen saturation was measured at rest in 94 subjects randomly elected from a diverse population of individuals. This sample consisted of 38 males and 65 females, with the age ranging from 18 - 70. There were 68 light-skinned individuals and 35 with darker skin comprising various ethnic and cultural backgrounds. Mean regional cerebral hemoglobin oxygen saturation was recorded as 67.14 plus or minus 8.84%. The association of the mean regional cerebral hemoglobin oxygen saturation in various group of individuals in relationship of their age, race, sex and skin color is examined.

  18. Molecular basis of human cerebral malaria development.

    Science.gov (United States)

    Wah, Saw Thu; Hananantachai, Hathairad; Kerdpin, Usanee; Plabplueng, Chotiros; Prachayasittikul, Virapong; Nuchnoi, Pornlada

    2016-01-01

    Cerebral malaria is still a deleterious health problem in tropical countries. The wide spread of malarial drug resistance and the lack of an effective vaccine are obstacles for disease management and prevention. Parasite and human genetic factors play important roles in malaria susceptibility and disease severity. The malaria parasite exerted a potent selective signature on the human genome, which is apparent in the genetic polymorphism landscape of genes related to pathogenesis. Currently, much genomic data and a novel body of knowledge, including the identification of microRNAs, are being increasingly accumulated for the development of laboratory testing cassettes for cerebral malaria prevention. Therefore, understanding of the underlying complex molecular basis of cerebral malaria is important for the design of strategy for cerebral malaria treatment and control.

  19. Gluconeogenesis and fasting in cerebral malaria

    NARCIS (Netherlands)

    van Thien, H.; Ackermans, M. T.; Weverling, G. J.; Dang Vinh, T.; Endert, E.; Kager, P. A.; Sauerwein, H. P.

    2004-01-01

    BACKGROUND: In healthy subjects after an overnight fast, glucose production is for approximately 50% derived from glycogenolysis. If the fast is prolonged, glucose production decreases due to a decline in glycogenolysis, while gluconeogenesis remains stable. In cerebral malaria, glucose production

  20. Cerebral microcirculation during experimental normovolaemic anaemia

    Directory of Open Access Journals (Sweden)

    Judith eBellapart

    2016-02-01

    Full Text Available Anaemia is accepted amongst critically ill patients as an alternative to elective blood transfusion. This practice has been extrapolated to head injury patients with only one study comparing the effects of mild anaemia on neurological outcome. There are no studies quantifying microcirculation during anaemia. Experimental studies suggest that anaemia leads to cerebral hypoxia and increased rates of infarction, but the lack of clinical equipoise when testing the cerebral effects of transfusion amongst critically injured patients, supports the need of experimental studies. The aim of this study was to quantify cerebral microcirculation and the potential presence of axonal damage in an experimental model exposed to normovolaemic anaemia, with the intention of describing possible limitations within management practices in critically ill patients. Under non-recovered anaesthesia, six Merino sheep were instrumented using an intracardiac transeptal catheter to inject coded microspheres into the left atrium to ensure systemic and non-chaotic distribution. Cytometric analyses quantified cerebral microcirculation at specific regions of the brain. Amyloid precursor protein staining was used as an indicator of axonal damage. Animals were exposed to normovolaemic anaemia by blood extractions from the indwelling arterial catheter with simultaneous fluid replacement through a venous central catheter. Simultaneous data recording from cerebral tissue oxygenation, intracranial pressure and cardiac output was monitored. A regression model was used to examine the effects of anaemia on microcirculation with a mixed model to control for repeated measures. Homogeneous and normal cerebral microcirculation with no evidence of axonal damage was present in all cerebral regions, with no temporal variability, concluding that acute normovolaemic anaemia does not result in short term effects on cerebral microcirculation in the ovine brain.

  1. Chronic cerebral ischemia, neuroplasticity, possibilities of therapy

    Directory of Open Access Journals (Sweden)

    E. I. Chukanova

    2017-01-01

    Full Text Available The paper presents current views on the pathogenetic mechanisms of cerebral ischemia. It discusses the role of neurotrophins in the processes of neuroplasticity. Experimental and clinical studies of the neuropeptide drug Cerebrolysin are reviewed. The authors describe in detail the results of the clinical trial and a health economic analysis of the effects of Cerebrolysin on the time course of clinical changes, progression, and risk of exacerbations in patients with chronic cerebral ischemia. 

  2. Cystatin C modulates cerebral beta-amyloidosis.

    Science.gov (United States)

    Kaeser, Stephan A; Herzig, Martin C; Coomaraswamy, Janaky; Kilger, Ellen; Selenica, Maj-Linda; Winkler, David T; Staufenbiel, Matthias; Levy, Efrat; Grubb, Anders; Jucker, Mathias

    2007-12-01

    The CST3 Thr25 allele of CST3, which encodes cystatin C, leads to reduced cystatin C secretion and conveys susceptibility to Alzheimer's disease. Here we show that overexpression of human cystatin C in brains of APP-transgenic mice reduces cerebral amyloid-beta deposition and that cystatin C binds amyloid-beta and inhibits its fibril formation. Our results suggest that cystatin C concentrations modulate cerebral amyloidosis risk and provide an opportunity for genetic risk assessment and therapeutic interventions.

  3. Treatment of cerebral aspergillosis after liver transplantation.

    Science.gov (United States)

    Polo, J M; Fábrega, E; Casafont, F; Fariñas, M C; Salesa, R; Vázquez, A; Berciano, J

    1992-09-01

    We report the treatment of cerebral aspergillosis with amphotericin B, flucytosine, surgery, and liposomal amphotericin B (L-AmB) after a liver transplant. The patient died 2 months after cessation of antifungal therapy, as a consequence of multiple-system organ failure. The only relevant postmortem finding in the brain was a small, encapsulated abscess containing hyphae. This case indicates that L-AmB is an effective alternative drug for cerebral aspergillosis.

  4. Cerebral biomarkers in women with preeclampsia

    OpenAIRE

    Bergman, Lina

    2017-01-01

    Preeclampsia and eclampsia are among the most common causes of maternal and fetal mortality and morbidity worldwide. There are no reliable means to predict eclampsia or cerebral edema in women with preeclampsia and knowledge of the brain involvement in preeclampsia is still limited. S100B and neuron specific enolase (NSE) are two cerebral biomarkers of glial- and neuronal origin respectively. They are used as predictors for neurological outcome after traumatic brain injuries and cardiac arres...

  5. Wearable wireless cerebral oximeter (Conference Presentation)

    Science.gov (United States)

    Zhang, Xin; Jiang, Tianzi

    2016-03-01

    Cerebral oximeters measure continuous cerebral oxygen saturation using near-infrared spectroscopy (NIRS) technology noninvasively. It has been involved into operating room setting to monitor oxygenation within patient's brain when surgeons are concerned that a patient's levels might drop. Recently, cerebral oxygen saturation has also been related with chronic cerebral vascular insufficiency (CCVI). Patients with CCVI would be benefited if there would be a wearable system to measure their cerebral oxygen saturation in need. However, there has yet to be a wearable wireless cerebral oximeter to measure the saturation in 24 hours. So we proposed to develop the wearable wireless cerebral oximeter. The mechanism of the system follows the NIRS technology. Emitted light at wavelengths of 740nm and 860nm are sent from the light source penetrating the skull and cerebrum, and the light detector(s) receives the light not absorbed during the light pathway through the skull and cerebrum. The amount of oxygen absorbed within the brain is the difference between the amount of light sent out and received by the probe, which can be used to calculate the percentage of oxygen saturation. In the system, it has one source and four detectors. The source, located in the middle of forehead, can emit two near infrared light, 740nm and 860nm. Two detectors are arranged in one side in 2 centimeters and 3 centimeters from the source. Their measurements are used to calculate the saturation in the cerebral cortex. The system has included the rechargeable lithium battery and Bluetooth smart wireless micro-computer unit.

  6. Treatment of Spasticity in Cerebral Palsy

    OpenAIRE

    Gül Mete Civelek; Ayçe Atalay

    2016-01-01

    The cerebral palsy diagnosis is a clinical one and it includes motor development delay, abnormal muscle tone and hyperreflexia. Muscle weakness, spasticity, loss of coordination, the continuation of the primitive reflexes and non-developed normal motor control are often seen in children with cerebral palsy. Spasticity is the velocity dependent increase in the resistance against passive muscle stretching. Spasticity treatment program should be established after detailed evaluation of degree an...

  7. International Musicological Conference Young Musicology Prague: Czech and European Avant-garde Music of the Early 20th Century, Kabinet hudební historie Etnologického ústavu AV ČR, Praha 5.–8. září 2016

    Czech Academy of Sciences Publication Activity Database

    Pirner, Jan

    2017-01-01

    Roč. 54, č. 2 (2017), s. 236-237 ISSN 0018-7003. [International Musicological Conference Young Musicology Prague: Czech and European Avant-garde Music of the Early 20th Century. Prague, 05.10.2016-08.10.2016] Institutional support: RVO:68378076 Keywords : 20th Century * Young Musicology * Conference Subject RIV: AL - Art, Architecture, Cultural Heritage

  8. Qualité de vie et vécu de la maladie, avant et après hystérectomie vaginale, chez les femmes admises au Centre Hospitalier Universitaire de Brazzaville

    Science.gov (United States)

    Mbongo, Jean Alfred; Mouanga, Alain; Miabaou, Didace Massamba; Nzelie, Aya; Iloki, Léon Hervé

    2016-01-01

    Toute maladie est un mal en soi qu’il faut éradiquer car elle altère souvent de façon significative la qualité de la vie. L’hystérectomie vaginale est indiquée pour les patientes qui présentent certaines affections gynécologiques graves, elle est donc bénéfique mais, peut également avoir une répercussion néfaste sur la qualité de vie de la femme. Ainsi nous avons voulu explorer le vécu de la maladie et de l’hystérectomie vaginale (HV) des femmes avant et après l’intervention chirurgicale. Nous avons effectué une étude prospective qualitative, à recueil clinique sur une période de 12 mois; qui a concerné les femmes, ayant subi une hystérectomie vaginale. Celles n’ayant pas accepté de participer à l’étude, ou n’ayant pas de contact téléphonique n’ont pas été incluses. Pendant la maladie, le vécu des femmes a été: l’inconfort sexuel 26/40 (65%); les saignements génitaux 12/40 (30%); les douleurs pelviennes 13/40 (32,5%). En Post-opératoire, ont été noté les dyspareunies transitoires30/40 (75%) ; les céphalées secondaires à l’anesthésie 4/40 (10%). Le vécu psychologique a été dominé avant l’HV par la peur de la chirurgie chez toutes les patientes, les troubles du sommeil 38/40 (95%), l’angoisse 30 /40(75%), un sentiment de honte lié aux difficultés à accomplir l’acte sexuel en raison du prolapsus 26/40(65%) et/ ou en raison des saignements génitaux, dus au fibrome utérin 14/40(35%). Le sentiment de la perte de féminité était déclaré par 26/40 femmes porteuses de prolapsus utérin (65%), la modification de l’estime de soi 26/40 (65%). Ces appréciations subjectives ont été améliorées avec l’HV, contre balançant la perte de leur organe de reproduction. Aucune information n’a été donnée par les femmes à leurs proches et aux membres de la famille avant la chirurgie, traduisant ainsi leur sentiment de gène ou de honte. L’arrêt des symptômes a été observé dans tous les

  9. Hereditary cerebral small vessel disease and stroke.

    Science.gov (United States)

    Søndergaard, Christian Baastrup; Nielsen, Jørgen Erik; Hansen, Christine Krarup; Christensen, Hanne

    2017-04-01

    Cerebral small vessel disease is considered hereditary in about 5% of patients and is characterized by lacunar infarcts and white matter hyperintensities on MRI. Several monogenic hereditary diseases causing cerebral small vessel disease and stroke have been identified. The purpose of this systematic review is to provide a guide for determining when to consider molecular genetic testing in patients presenting with small vessel disease and stroke. CADASIL, CARASIL, collagen type IV mutations (including PADMAL), retinal vasculopathy with cerebral leukodystrophy, Fabry disease, hereditary cerebral hemorrhage with amyloidosis, and forkhead box C1 mutations are described in terms of genetics, pathology, clinical manifestation, imaging, and diagnosis. These monogenic disorders are often characterized by early-age stroke, but also by migraine, mood disturbances, vascular dementia and often gait disturbances. Some also present with extra-cerebral manifestations such as microangiopathy of the eyes and kidneys. Many present with clinically recognizable syndromes. Investigations include a thorough family medical history, medical history, neurological examination, neuroimaging, often supplemented by specific examinations e.g of the of vision, retinal changes, as well as kidney and heart function. However molecular genetic analysis is the final gold standard of diagnosis. There are increasing numbers of reports on new monogenic syndromes causing cerebral small vessel disease. Genetic counseling is important. Enzyme replacement therapy is possible in Fabry disease, but treatment options remain overall very limited. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Purine Metabolism in Acute Cerebral Ischemia

    Directory of Open Access Journals (Sweden)

    Ye. V. Oreshnikov

    2008-01-01

    Full Text Available Objective: to study the specific features of purine metabolism in clinically significant acute cerebral ischemia. Subjects and materials. Three hundred and fifty patients with the acutest cerebral ischemic stroke were examined. The parameters of gas and electrolyte composition, acid-base balance, the levels of malonic dialdehyde, adenine, guanine, hypox-anthine, xanthine, and uric acid, and the activity of xanthine oxidase were determined in arterial and venous bloods and spinal fluid. Results. In ischemic stroke, hyperuricemia reflects the severity of cerebral metabolic disturbances, hemodynamic instability, hypercoagulation susceptiility, and the extent of neurological deficit. In ischemic stroke, hyperuri-corachia is accompanied by the higher spinal fluid levels of adenine, guanine, hypoxanthine, and xanthine and it is an indirect indicator of respiratory disorders of central genesis, systemic acidosis, hypercoagulation susceptibility, free radical oxidation activation, the intensity of a stressor response to cerebral ischemia, cerebral metabolic disturbances, the depth of reduced consciousness, and the severity of neurological deficit. Conclusion. The high venous blood activity of xanthine oxidase in ischemic stroke is associated with the better neurological parameters in all follow-up periods, the better early functional outcome, and lower mortality rates. Key words: hyperuricemia, stroke, xanthine oxidase, uric acid, cerebral ischemia.

  11. Association of cerebral palsy with epilepsy.

    Science.gov (United States)

    Kaushik, A; Agarwal, R P; Sadhna

    1997-10-01

    Fifty patients of various types of cerebral palsy were studied to find out an association between cerebral palsy, EEG abnormalities and development quotient. Seventy-six per cent patients had spastic cerebral palsy. Hypotonic cerebral palsy was the next common type (14%). Athetosis and ataxic forms were found to be rare (2% each). Epilepsy was associated with 56% patients. Clinical types of seizures observed were: Generalised tonic-clonic (43%), myoclonic (17.9%), generalised tonic (10.7%), partial simple (10.7%) and partial complex (17.9%). The incidence of seizures was highest in hypotonic type in which 85.7% had epilepsy. Mean developmental quotient of cerebral palsy patients was 34.9% with maximum retardation in hypotonic cerebral palsy (25.14%). Sixty per cent of patients had abnormal EEG, out of these hypotonic patients had maximum (70%) chances of EEG abnormality followed by spastic patients (55%). Developmental retardation was more severe statistically in the patients with abnormal EEG than normal EEG.

  12. Is fasting necessary for elective cerebral angiography?

    Science.gov (United States)

    Kwon, O-K; Oh, C W; Park, H; Bang, J S; Bae, H-J; Han, M K; Park, S-H; Han, M H; Kang, H-S; Park, S-K; Whang, G; Kim, B-C; Jin, S-C

    2011-05-01

    In order to prevent unexpected events such as aspiration pneumonia, cerebral angiography has been performed under fasting in most cases. We investigated prospectively the necessity of fasting before elective cerebral angiography. The study is an open-labeled clinical trial without random allocation. In total, 2554 patients who underwent elective cerebral angiography were evaluated on development of nausea, vomiting, and pulmonary aspiration during and after angiography. Potential risks and benefits associated with fasting were provided in written documents and through personal counseling to patients before the procedure. The patients chose their fasting or nonfasting option. No restriction in diet was given after angiography. The patients were observed for 24 hours. Nausea and vomiting during and within 1 hour after angiography was considered as a positive event associated with cerebral angiography. The overall incidence of nausea and vomiting during and within 1 hour after angiography was 1.05% (27/2554 patients). There was no patient with pulmonary aspiration. No statistical difference in nausea and vomiting development between the fasting and the diet groups was found. The incidence of nausea and vomiting associated with cerebral angiography is low and not affected by diet or fasting. Pulmonary aspiration had no difference between the diet and the fasting group. Our study suggests that fasting may not be necessary for patients who undergo elective cerebral angiography.

  13. CT findings of early acute cerebral infarction

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hoon; Choi, Woo Suk; Ryu, Kyung Nam [Kyung Hee University Hospital, Seoul (Korea, Republic of)

    1992-11-15

    The CT findings of the acute cerebral infarction are well known. However the CT findings of early stroke within 24 hours of the onset have not been sufficiently reported. The purpose of this study is to evaluate early acute cerebral infarction on CT within 24 hours after ictus. The early and accurate CT diagnosis could lead to the appropriate therapy and improved outcome of the patients. Authors retrospectively analyzed 16 patients with early acute cerebral infarction. Acute cerebral infarction was confirmed by follow-up CT in 11 patients, SPECT in 4 patients, and MRI in 1 patient. The CT findings of early acute cerebral infarction include effacement of cortical sulci or cistern (n = 16, 100%), hyperattenuation of MCA (n = 3), obscuration of lentiform nucleus (n = 6), loss of insular ribbon (n = 6) and subtle low density in hemisphere (n = 5). The most frequent finding was effacement of cortical sulci in our study, and it was thought to be the most important sign of early acute cerebral infarction.

  14. Cerebral Radionecrosis in Patients with Nasopharyngeal Carcinoma

    Directory of Open Access Journals (Sweden)

    Ying-Che Hsu

    2005-10-01

    Full Text Available This study involved seven patients with cerebral radionecrosis following radiation therapy for nasopharyngeal carcinoma (NPC. Their charts were reviewed and the relationship of extracranial malignancies to cerebral radionecrosis was investigated. The radiation dose ranged from 70 to 135 Gy, and the latency was from 6 to 39 months. Two of seven patients died of NPC-related complications during follow-up. The crude incidence of cerebral radionecrosis in patients with NPC was 0.93% in our series. Improvement of symptoms could be achieved by corticosteroid therapy, with or without surgery. In a review of the literature, there were 306 cases of cerebral radionecrosis in extracranial malignancies. The nasopharynx is the most common primary site in cerebral radionecrosis of extracranial malignancies, followed by the scalp and sinonasal tract. The 3-year overall survival rate in our series was 68.57%, as provided by the Kaplan-Meier product limited method. Cerebral radionecrosis in NPC patients should be differentiated from tumor recurrence, in order to apply the appropriate treatment.

  15. Ocular problems in children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Esra Ayhan Tuzcu

    2012-09-01

    Full Text Available The aim of this study is to evaluate eye problemsin children with cerebral palsy in our region.Materials and Methods: 90 patients which was diagnosedas cerebral palsy, treated and followed up in PediatricNeurology Department of Mustafa Kemal University,were included to this study. The history was taken, anda physical examination was performed to determine theetiology of the disease and type of SP. All of the patientswere underwent a detailed ophthalmological examinationincluding visual acuity, refractive error, amblyopia, strabismus,nystagmus and fundus examination.Results: Totally 90 patients, 51 male and 39 female,were included to the study. When the etiologic factorswere evaluated, the asphyxia was seen in 33.3% of thepatients. The most common type of cerebral palsy wasspastic quadriplegia at the rate of 43.3%. Eye problemswere detected in 60% of our cases. Of this, 54.4% wererefractive errors, 35.6% were strabismus, and 22.2%were optic nerve pathologies. Amblyopia was found in11.1% of cases. Although strabismus is more common inspastic diplegia type of cerebral palsy, there was no statisticallysignificant differenceConclusions: In conclusion, eye problems are commonin children with cerebral palsy. Therefore, we recommendroutine eye examination in these patients due to be beneficialin reducing the detection and communication difficulties.Key words: Cerebral palsy, refractive error, strabismus,optic atrophy

  16. Cerebral hemodynamics at altitude: effects of hyperventilation and acclimatization on cerebral blood flow and oxygenation.

    Science.gov (United States)

    Sanborn, Matthew R; Edsell, Mark E; Kim, Meeri N; Mesquita, Rickson; Putt, Mary E; Imray, Chris; Yow, Heng; Wilson, Mark H; Yodh, Arjun G; Grocott, Mike; Martin, Daniel S

    2015-06-01

    Alterations in cerebral blood flow (CBF) and cerebral oxygenation are implicated in altitude-associated diseases. We assessed the dynamic changes in CBF and peripheral and cerebral oxygenation engendered by ascent to altitude with partial acclimatization and hyperventilation using a combination of near-infrared spectroscopy, transcranial Doppler ultrasound, and diffuse correlation spectroscopy. Peripheral (Spo2) and cerebral (Scto2) oxygenation, end-tidal carbon dioxide (ETCO2), and cerebral hemodynamics were studied in 12 subjects using transcranial Doppler and diffuse correlation spectroscopy (DCS) at 75 m and then 2 days and 7 days after ascending to 4559 m above sea level. After obtaining baseline measurements, subjects hyperventilated to reduce baseline ETCO2 by 50%, and a further set of measurements were obtained. Cerebral oxygenation and peripheral oxygenation showed a divergent response, with cerebral oxygenation decreasing at day 2 and decreasing further at day 7 at altitude, whereas peripheral oxygenation decreased on day 2 before partially rebounding on day 7. Cerebral oxygenation decreased after hyperventilation at sea level (Scto2 from 68.8% to 63.5%; Phyperventilation after 2 days at altitude (Scto2 from 65.6% to 69.9%; P=.001), and did not change after hyperventilation after 7 days at altitude (Scto2 from 62.2% to 63.3%; P=.35). An intensification of the normal cerebral hypocapnic vasoconstrictive response occurred after partial acclimatization in the setting of divergent peripheral and cerebral oxygenation. This may help explain why hyperventilation fails to improve cerebral oxygenation after partial acclimatization as it does after initial ascent. The use of DCS is feasible at altitude and provides a direct measure of CBF indices with high temporal resolution. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  17. Utilisation de traceurs radioactifs pour l'évaluation du recrutement des leucocytes et des échanges vasculaires au niveau d'organes in~vivo. Description d'une méthode et discussion des problèmes d'interprétation sur quelques exemples

    Science.gov (United States)

    Bureau, M. F.

    1997-03-01

    An experimental method using simultaneously different γ emiter tracers was developed to evaluate inflammation in vivo. Experiments were performed on the anaesthetized guinea-pig to test pulmonary effects of inflammatory agents. Red blood cells, albumin and inflammatory cells (platelets or leucocytes) radiolabelled with 99m technetium, 131 iodine and 111 indium respectively were injected i.v. Their radioactivities were measured on a pulmonary region by external detection and on blood samples in a well type counter. From these measurements variations of the lung contents in red blood cells, extravascular albumin and non circulating leucocytes during inflammatory stimulation were evaluated. These parameters axe indexes of blood perfusion, vascular exchanges and leucocyte sequestration respectively. Fiability of the method and meaning of the parameters evaluated are discussed. Une méthode expérimentale utilisant simultanément différents traceurs γ a été développée pour évaluer l'inflammation in vivo. Des expériences ont été réalisées chez le cobaye anesthésié pour tester l'effet pulmonaire d'agents inflammatoires. Des globules rouges, de l'albumine et des cellules inflammatoires (plaquettes ou leucocytes) radiomarqués respectivement au technetium 99m, à l'iode 131 et à l'indium 111 sont injectés i.v. Leurs radioactivités sont mesurées sur une région pulmonaire par détection externe et sur des échantillons sanguins au compteur puit. À partir de ces mesures sont évaluées les variations des contenus pulmonaires en globules rouges, en albumine extravasculaire et en leucocytes non circulants lors d'une stimulation inflammatoire. Ces paramètres sont corrélés aux modifications de la perfusion, des échanges vasculaires et de la séquestration leucocytaire. La fiabilité de la méthode et la signification des paramètres évalués sont discutées.

  18. Trends in incidence and early outcomes in a Black Afro-Caribbean population from 1999 to 2012: Etude Réalisée en Martinique et Centrée sur l'Incidence des Accidents Vasculaires Cérébraux II Study.

    Science.gov (United States)

    Olindo, Stephane; Chausson, Nicolas; Mejdoubi, Mehdi; Jeannin, Severine; Rosillette, Karine; Saint-Vil, Martine; Signate, Aissatou; Edimonana-Kaptue, Mireille; Larraillet, Veronique; Cabre, Philippe; Smadja, Didier; Joux, Julien

    2014-11-01

    Seldom studies are available on trends in stroke incidence in blacks. We aimed to evaluate whether stroke risk prevention policies modified first-ever stroke incidence and outcomes in the black Afro-Caribbean population of Martinique. Etude Réalisée en Martinique et Centrée sur l'Incidence des Accidents Vasculaires Cérébraux (ERMANCIA) I and II are 2 sequential prospective population-based epidemiological studies. There have assessed temporal trends in first-ever stroke incidence, risk factors, pathological types, and early outcomes in the black Afro-Caribbean population of Martinique comparing two 12-month periods (1998-1999 and 2011-2012). Crude and age-standardized incidence and 30-day outcomes for stroke in the 2 study periods were compared using Poisson regression. We identified 580 and 544 first-ever strokes in the 2 studies. World age-standardized incidence rates decreased by 30.6% in overall (111 [95% confidence interval, 102-120] versus 77 [95% confidence interval, 70-84]). Rate decline was greater in women than in men (34% versus 26%) particularly in women aged 65 to 74 years (-69%) and 75 to 84 years (-43%). Frequencies of hypertension and diabetes mellitus were unchanged, whereas dyslipidemia, smoking, and atrial fibrillation significantly increased. Only ischemic stroke types showed significant rate reduction in overall and in women, incidence rate ratio (95% confidence intervals) of 0.69 (0.50-0.97) and 0.61 (0.42-0.88), respectively. The overall 30-day case-fatality ratio remained stable (19.3%/17.6%), whereas a better 30-day outcome was found (modified Rankin Score, ≤2 in 47%/37.6%; P=0.03). Over 13 years, there has been a significant decrease (30.6%) in the age-specific first-ever stroke incidence in our Afro-Carribean population. Although prevention policies seem effective, we need to focus on new risk factors limitation and on male population adherence to prevention program. © 2014 American Heart Association, Inc.

  19. Cerebral oxygen extraction, oxygen consumption, and regional cerebral blood flow during the aura phase of migraine

    DEFF Research Database (Denmark)

    Friberg, L; Olesen, Jes; Lassen, N A

    1994-01-01

    The aura phase of migraine is associated with focal blood flow changes, but it has been largely unknown whether these changes are correlated to changes in the cerebral metabolism.......The aura phase of migraine is associated with focal blood flow changes, but it has been largely unknown whether these changes are correlated to changes in the cerebral metabolism....

  20. The early markers for later dyskinetic cerebral palsy are different from those for spastic cerebral palsy

    NARCIS (Netherlands)

    Einspieler, C; Cioni, G; Paolicelli, PB; Bos, AF; Dressler, A; Ferrari, F; Roversi, MF; Prechtl, HFR

    Qualitative abnormalities of spontaneous motor activity in new-borns and young infants are early predictive markers for later spastic cerebral palsy. Aim of this research was to identify which motor patterns may be specific for later dyskinetic cerebral palsy. In a large, prospectively performed

  1. Diagnostic approach to cerebral aneurysms

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Vitor Mendes [Division of Diagnostic and Interventional Neuroradiology, Geneva University Hospitals (Switzerland); Bijlenga, Philippe [Department of Neurosurgery, Geneva University Hospitals (Switzerland); Marcos, Ana [Division of Diagnostic and Interventional Neuroradiology, Geneva University Hospitals (Switzerland); Schaller, Karl [Department of Neurosurgery, Geneva University Hospitals (Switzerland); Lovblad, Karl-Olof, E-mail: Karl-olof.lovblad@hcuge.ch [Division of Diagnostic and Interventional Neuroradiology, Geneva University Hospitals (Switzerland)

    2013-10-01

    Cerebral aneurysms are an important cause of morbidity and mortality due to their causal effect in non-traumatic subarachnoid hemorrhage. Neurosurgical progress in the 20th century helped to improve patient outcomes greatly. In recent years, techniques such as intravascular treatment by coiling and/or stenting have found an additional place in the management of the disease. With the development of less and less invasive surgical and endovascular techniques, there has also been a continuous development in imaging techniques that have led to our current situation where we dispose of CT and MR techniques that can help improve treatment planning greatly. CT is able to detect and together with its adjunct techniques CT angiography and CT perfusion, it can allow us to provide the physicians in charge with a detailed image of the aneurysm, the feeding vessels as well as the status of blood flow to the brain. Angiography has evolved by becoming the standard tool for guidance during decision making for whatever therapy is being envisioned be it endovascular procedures and or surgery and has even progressed more recently due to the development of so-called flat panel technology that now allows to acquire CT-like images during and directly after an intervention. Thus nowadays, the diagnostic and interventional techniques and procedures have become so much entwined as to be considered a whole.

  2. Cerebral oxygenation in preterm infants.

    Science.gov (United States)

    Fyfe, Karinna L; Yiallourou, Stephanie R; Wong, Flora Y; Odoi, Alexsandria; Walker, Adrian M; Horne, Rosemary S C

    2014-09-01

    Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known about the effects of sleeping position on TOI and MAP in preterm infants. We aimed to examine TOI and MAP in preterm infants after term-equivalent age, during the period of greatest SIDS risk. Thirty-five preterm and 17 term infants underwent daytime polysomnography, including measurement of TOI (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and MAP (Finapress Medical Systems, Amsterdam, Netherlands) at 2 to 4 weeks, 2 to 3 months, and 5 to 6 months postterm age. Infants slept prone and supine in active and quiet sleep. The effects of sleep state and position were determined by using 2-way repeated measures analysis of variance and of preterm birth by using 2-way analysis of variance. In preterm infants, TOI was significantly lower when prone compared with supine in both sleep states at all ages (P preterm compared with term infants at 2 to 4 weeks, in both positions (P preterm infants in the prone position at 2 to 3 months (P position in preterm infants and is lower compared with age-matched term infants, predominantly in the prone position when MAP is also reduced. This may contribute to their increased SIDS risk. Copyright © 2014 by the American Academy of Pediatrics.

  3. Hemorrhagic stroke and cerebral paragonimiasis.

    Science.gov (United States)

    Xia, Yong; Ju, Yan; Chen, Jing; You, Chao

    2014-11-01

    We retrospectively analyzed the clinical and imaging characteristics, diagnosis, and treatment outcomes of 10 patients with hemorrhagic cerebral paragonimiasis (CP), and we evaluated the influence of Paragonimus infection on cerebrovascular damage. Ten patients (7 male and 3 female; median age 15.7 years, range 4-46 years) with hemorrhagic CP were diagnosed between April 2009 and January 2013. All patients underwent the head computed tomography scans and 9 patients underwent MRI examinations. Four patients underwent computed tomographic angiography, magnetic resonance angiography, and digital subtraction angiography. Liquid-based cytological examination of cerebrospinal fluid was performed in 7 patients. Follow-up examinations were performed for 9 cases for a period of 12 to 62 months. Hemorrhagic CP accounted for 37% of CP cases (10/27). No patients were initially diagnosed with CP. The major symptoms of hemorrhagic CP included acute headache, vomiting, hemiparalysis, epilepsy, blurred vision, sensory impairment, and tinnitus. Four cases were surgically treated. Most symptoms markedly improved, but fine motor dysfunction and mental dysfunction remained in 3 surgical patients. Hemorrhagic stroke typically occurred during the acute stage and in the early stages of further Paragonimus migration. Delay of treatment increased the risk of initial and recurrent stroke. © 2014 American Heart Association, Inc.

  4. [Cerebral amyloid angiopathy and dementia].

    Science.gov (United States)

    Berlit, P; Keyvani, K; Krämer, M; Weber, R

    2015-10-01

    Cerebral amyloid angiopathy (CAA) is one of the most frequent causes of intracerebral hemorrhage (ICH). The deposition of beta amyloid leads to vascular fragility due to degeneration of vessel walls, formation of microaneurysms particularly in cortical blood vessels and fibrinoid vessel wall necrosis. The Congo red positive amyloid deposits are biochemically similar to the material comprising senile plaques in Alzheimer's disease. Recurrent or multiple simultaneous hemorrhages particularly in older patients should raise the suspicion of CAA. Gradient echo magnetic resonance imaging (MRI) is a sensitive, non-invasive technique for identifying even very small hemorrhages and superficial siderosis, which may cause transient symptoms in CAA. There is also a correlation between CAA, microbleeding and cognitive decline. Inflammatory variants of CAA must be suspected whenever patients present with progressive dementia, headache and multifocal symptoms in association with CAA findings in MRI. Histopathologically, a distinction is made between CAA-related inflammation (CAA-ri) with perivascular inflammatory infiltrates and amyloid beta-related angiitis (ABRA) with histological detection of transmural vasculitis. Inflammatory variants should be treated with corticosteroids and immunosuppressants.

  5. Cerebral CT of ischaemic lesions

    Energy Technology Data Exchange (ETDEWEB)

    Aulich, A.

    1981-11-25

    The diagnosis of stroke must first be established by clinical examination. CT has proved useful for confirmation of the diagnosis and provides a global intracranial picture of morphological changes in cerebral vascular diseases. A hemorrhage can be recognized with certainty at the first CT examination as the cause of the stroke, but in the detection of a lesion due to ischemia an important role is played by the correct choice of the time of examination, and in some cases also of the check-up with contrast medium. The differential diagnosis between infarct in the acute stage and encephalitis or gliomas of low-grade malignity can be difficult. A decision can often only be made after a series of examinations. Postmalacial conditions are often difficult to differentiate from defects due to other causes, such as hemorrhage, head injury, postoperative states and after encephalitis. A knowledge of the anamnesis and the clinical findings is indispensable for CT evaluation. In assessing the prognosis before vascular surgery on the extracranial brain-supplying vessels the performance of a CT examination should be advised. A warning is given against the use of CT as a screening method.

  6. Cerebral vasospasm in acute porphyria.

    Science.gov (United States)

    Olivier, P; Van Melkebeke, D; Honoré, P-J; Defreyne, L; Hemelsoet, D

    2017-09-01

    Porphyrias are a group of inherited metabolic disorders resulting from a specific deficiency along the pathway of haem biosynthesis. A clinical classification distinguishes acute from non-acute porphyrias considering the occurrence of life-threatening neurovisceral attacks, presenting with abdominal pain, neuropsychiatric disturbance and neuropathy. Vasospasm is a very rare complication that can occur in all major types of acute porphyria. We describe a porphyric crisis with vasospasm in a woman with previously undiagnosed acute porphyria. Furthermore we performed a systematic review by searching the electronic database Pubmed/MEDLINE for additional data in published studies of vasospasm in acute porphyria. Overall, 9 case reports reporting on 11 patients who suffered vasospasm during an exacerbation of acute porphyria were identified. All of the reported patients were women and the mean age was 29.4 years. When brain MRI was performed, T2-hyperintense lesions, consistent with ischaemic changes, were observed in most patients (10/11, 91%). Although the genetic pathogenesis of the disease is well understood, the precise mechanisms to explain neurologic involvement in acute porphyria remain unclear. Acute porphyria is an unusual and rare cause of vasospasm. However, considering porphyria in patients with unexplained cerebral vasospasm, especially in women of childbearing age, is crucial given the severity of possible complications and the available treatment options. © 2017 EAN.

  7. [Muscle weakness in cerebral palsy].

    Science.gov (United States)

    Givon, Uri

    2009-01-01

    Over the last two decades, muscle weakness has been shown to be a major component of cerebral palsy (CP) pathology. Caused by multiple etiologies including variations in the muscle fiber type, pathologic motor unit function, co-contraction of agonists and antagonists, and muscle size and rigidity, weakness interferes with function and leads to limited function and participation. Muscle strength was found to be associated with walking ability and with functional scales. Children with CP were found to be weaker than typically developing children, and differences were found with respect to muscle groups in children with CP. Muscle weakness should be evaluated as objectively as possible to improve the quality of diagnosis and treatment. Manual muscle testing is not sufficient for evaluation, and instrumented muscle testing is validated in CP. Muscle strengthening is an important part of treatment of CP. Several methods of strengthening have been described. Muscle lengthening and other spasticity-modifying therapies have been shown to have a positive effect on muscle strength. Children who participated in muscle strengthening programs had a better quality of life and improved function.

  8. Cerebral oxygen metabolism and cerebral blood flow in man during light sleep (stage 2)

    DEFF Research Database (Denmark)

    Madsen, P L; Schmidt, J F; Holm, S

    1991-01-01

    We measured cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) during light sleep (stage 2) in 8 young healthy volunteers using the Kety-Schmidt technique with 133Xe as the inert gas. Measurements were performed during wakefulness and light sleep as verified by standard...... polysomnography. Unlike our previous study in man showing a highly significant 25% decrease in CMRO2 during deep sleep (stage 3-4) we found a modest but statistically significant decrease of 5% in CMRO2 during stage 2 sleep. Deep and light sleep are both characterized by an almost complete lack of mental activity....... They differ in respect of arousal threshold as a stronger stimulus is required to awaken a subject from deep sleep as compared to light sleep. Our results suggest that during non-rapid eye movement sleep cerebral metabolism and thereby cerebral synaptic activity is correlated to cerebral readiness rather than...

  9. PRETERM BIRTH ASSOCIATION WITH CEREBRAL PALSY

    Directory of Open Access Journals (Sweden)

    Srinivasa Rao

    2015-04-01

    Full Text Available INTRODUCTION: Cerebral palsy ( CP is a group of permanent movement disorders that appear in early childhood. Preterm birth is the birth of baby before 37 completed weeks, a full term birth is birth at 37 to 42 weeks of gestation . AIM: To show the extent of association of preterm deliveries as a risk factor in development of cerebral palsy. MATERIALS AND METHODS: This r etrospective cohort study was conducted by eliciting history from the mothers of 99 cerebral palsy children who w ere treated in Rani Chandra Mani Devi Hospital, Visakhapatnam, Andhra Pradesh, India. De tailed history was taken from the mothers of 99 cerebral palsy children who were treated in this hospital. History regarding the period of gestation at which the child was born (preterm or full term, any previous history of pre - term delivery or abortions, was obtained from the mothers and the data analyzed . RESULTS: From this study it was observed the proportional association of pre - term births to cerebral palsy is 33 out 99 i.e., about 33.33%, Of these 33 cerebral palsy children highest association being with birth at 28 wks gestation (51 %. This study also shows th at the mothers with a previous history of preterm delivery have 14.4 times higher risk of subsequent pre term delivery; those with previous history of abortions have 5.7 times risk of pre - term delivery than mothers without such history. CONCLUSION: From th is study it was concluded that the pre - term birth plays a major role as a risk factor in the development of cerebral palsy with mothers having previous pre term delivery and previous abortions adding further to this risk.

  10. Association of Lead Levels and Cerebral Palsy.

    Science.gov (United States)

    Bansal, Neha; Aggarwal, Anju; Faridi, M M A; Sharma, Tusha; Baneerjee, B D

    2017-01-01

    Background: Cerebral palsy is a common motor disability in childhood. Raised lead levels affect cognition. Children with cerebral palsy may have raised lead levels, further impairing their residual cognitive motor and behavioral abilities. Environmental exposure and abnormal eating habits may lead to increased lead levels. Aims and Objectives: To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children. To correlate blood lead levels with environmental factors. Material and Methods:Design: Prospective case-control study. Setting: Tertiary care hospital. Participants: Cases comprised 34 children with cerebral palsy, and controls comprised 34 neurologically normal, age- and sex-matched children. Methods: Clinical and demographic details were recorded as per proforma. Detailed environmental history was recorded to know the source of exposure to lead. These children were investigated and treated as per protocol. Venous blood was collected in ethylenediaminetetraacetic acid vials for analysis of blood lead levels. Lead levels were estimated by Schimadzu Flame AA-6800 (atomic absorption spectrophotometer). Data were analyzed using SPSS version 17. P cerebral palsy cases and 2.89 ± 3.04 µg/dL in their controls (P cerebral palsy, 19 (55.88%) children had blood lead levels ≥5 µg/dL. Lead levels in children with pica were 12.33 ± 10.02 µg/dL in comparison to children with no history of pica, 6.70 ± 4.60 µg/dL (P = .029). No correlation was found between hemoglobin and blood lead levels in cases and controls. Conclusion: In our study, blood lead levels are raised in children with cerebral palsy. However, further studies are required to show effects of raised levels in these children.

  11. Association of Lead Levels and Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Neha Bansal MD

    2017-03-01

    Full Text Available Background: Cerebral palsy is a common motor disability in childhood. Raised lead levels affect cognition. Children with cerebral palsy may have raised lead levels, further impairing their residual cognitive motor and behavioral abilities. Environmental exposure and abnormal eating habits may lead to increased lead levels. Aims and Objectives: To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children. To correlate blood lead levels with environmental factors. Material and Methods: Design: Prospective case-control study. Setting: Tertiary care hospital. Participants: Cases comprised 34 children with cerebral palsy, and controls comprised 34 neurologically normal, age- and sex-matched children. Methods: Clinical and demographic details were recorded as per proforma. Detailed environmental history was recorded to know the source of exposure to lead. These children were investigated and treated as per protocol. Venous blood was collected in ethylenediaminetetraacetic acid vials for analysis of blood lead levels. Lead levels were estimated by Schimadzu Flame AA-6800 (atomic absorption spectrophotometer. Data were analyzed using SPSS version 17. P < .05 was taken as significant. Results: Mean blood lead levels were 9.20 ± 8.31 µg/dL in cerebral palsy cases and 2.89 ± 3.04 µg/dL in their controls (P < .001. Among children with cerebral palsy, 19 (55.88% children had blood lead levels ≥5 µg/dL. Lead levels in children with pica were 12.33 ± 10.02 µg/dL in comparison to children with no history of pica, 6.70 ± 4.60 µg/dL (P = .029. No correlation was found between hemoglobin and blood lead levels in cases and controls. Conclusion: In our study, blood lead levels are raised in children with cerebral palsy. However, further studies are required to show effects of raised levels in these children.

  12. Regional Cerebral Perfusion in Progressive Supranuclear Palsy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Yong; Lee, Ki Hyeong; Yoon, Byung Woo; Lee, Sang Bok; Jeon, Beom S. [Samsung Medical Center, Seoul (Korea, Republic of); Lee, Kyung Han; Lee, Myung Chul [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1996-03-15

    Progressive supranuclear palsy (PSP) is a Parkinson-plus syndrome characterized clinically by supranuclear ophthalmoplegia, pseudobulbar palsy, axial rigidity, bradykinesia, postural instability and dementia. Presence of dementia and lack of cortical histopathology suggest the derangement of cortical function by pathological changes in subcortical structures in PSP, which is supported by the pattern of behavioral changes and measurement of brain metabolism using positron emission tomography. This study was done to examine whether there are specific changes of regional cerebral perfusion in PSP and whether there is a correlation between severity of motor abnormaility and degree of changes in cerebral perfusion. We measured regional cerebral perfusion indices in 5 cortical and 2 subcortical areas in 6 patients with a clinical diagnosis of PSP and 6 healthy age and sex matched controls using Tc-99m-HMPAO SPECT. Compared with age and sex matched controls, only superior frontal regional perfusion index was significantly decreased in PSP (p<0.05). There was no correlation between the severity of the motor abnormality and any of the regional cerebral perfusion indices (p>0.05). We affirm the previous reports that perfusion in superior frontal cortex is decreased in PSP. Based on our results that there was no correlation between severity of motor abnormality and cerebral perfusion in the superior frontal cortex, nonmotoric symptoms including dementia needs to be looked at whether there is a correlation with the perfusion abnormality in superior frontal cortex

  13. Cerebral emboli and depressive symptoms in dementia.

    Science.gov (United States)

    Purandare, Nitin; Voshaar, Richard C Oude; Hardicre, Jayne; Byrne, Jane; McCollum, Charles; Burns, Alistair

    2006-09-01

    The vascular depression hypothesis and our recent findings of increased frequency of spontaneous cerebral emboli in dementia suggest that such emboli may be involved in the causation of depressive symptoms in dementia. To evaluate the association between spontaneous cerebral emboli and depressive symptoms in Alzheimer's disease and vascular dementia. In a cohort of 142 patients with dementia (72 with Alzheimer's disease and 70 with vascular dementia), the association between spontaneous cerebral emboli and clinically relevant depressive symptoms was examined using multiple logistic regression analyses. Spontaneous cerebral emboli were significantly more frequent in the patients with clinically relevant depressive symptoms (66 v. 37%, P=0.03). After adjustment for age, gender, Mini-Mental State Examination score, type of dementia and significant cardiovascular risk factors, the relationship remained significant (OR=3.47, 95% CI 1.10-10.97). Spontaneous cerebral emboli are associated with clinically relevant depressive symptoms in dementia, and further research is needed to explore the nature of this relationship.

  14. Gerstmann's syndrome associated with diagnostic cerebral angiography.

    Science.gov (United States)

    Wu, Yung-Tsan; Chen, Liang-Cheng; Lin, Shu-Lin; Chang, Shin-Tsu

    2013-01-01

    Gerstmann's syndrome is a rare neurological disorder characterized by right-left disorientation, finger agnosia, agraphia and acalculia. Several causes for the manifestation of this rare syndrome have been reported in previous publications; however, thus far, an association between secondary diagnostic cerebral angiography and Gerstmann's syndrome has not been reported. A 48-year-old woman diagnosed with subarachnoid haemorrhage underwent a secondary diagnostic cerebral angiography 7 months after the episode. The patient showed memory impairment, agraphia, acalculia, right-left disorientation, occasional errors in speech and finger agnosia accompanied by an acute infarction in the left middle cerebral artery territory. However, she showed excellent recovery after intensive rehabilitation and conservative treatment. The previously reported rate of permanent neurological complications associated with diagnostic cerebral angiography was very low (0-0.5%). To the best of the authors' knowledge, this is the first case report of Gerstmann's syndrome as a complication of cerebral angiography. This report discusses the complications associated with the neurological condition and emphasizes the need for early rehabilitation in cases of Gerstmann's syndrome.

  15. Bedside Monitoring of Cerebral Energy State During Cardiac Surgery

    DEFF Research Database (Denmark)

    Mölström, Simon; Nielsen, Troels H; Andersen, Claus

    2017-01-01

    OBJECTIVES: This study investigated whether the lactate-to-pyruvate (LP) ratio obtained by microdialysis (MD) of the cerebral venous outflow reflected a derangement of global cerebral energy state during cardiopulmonary bypass (CPB). DESIGN: Interventional, prospective, randomized study. SETTING:...

  16. Admission Hyperglycemia and Clinical Outcome in Cerebral Venous Thrombosis

    NARCIS (Netherlands)

    Zuurbier, Susanna M.; Hiltunen, Sini; Tatlisumak, Turgut; Peters, Guusje M.; Silvis, Suzanne M.; Haapaniemi, Elena; Kruyt, Nyika D.; Putaala, Jukka; Coutinho, Jonathan M.

    2016-01-01

    Background and Purpose-Admission hyperglycemia is associated with poor clinical outcome in ischemic and hemorrhagic stroke. Admission hyperglycemia has not been investigated in patients with cerebral venous thrombosis. Methods-Consecutive adult patients with cerebral venous thrombosis were included

  17. Gastrostomy tube feeding of children with cerebral palsy

    DEFF Research Database (Denmark)

    Dahlseng, Magnus O; Andersen, Guro L; DA Graca Andrada, Maria

    2012-01-01

    To compare the prevalence of gastrostomy tube feeding (GTF) of children with cerebral palsy (CP) in six European countries.......To compare the prevalence of gastrostomy tube feeding (GTF) of children with cerebral palsy (CP) in six European countries....

  18. Role of magnetic resonance venography in evaluation of cerebral ...

    African Journals Online (AJOL)

    Eman Abd-El Latif Abd-Elaziz El Damarawy

    2011-12-14

    Dec 14, 2011 ... Abbreviations: MRI, magnetic resonance imaging; MRV, magnetic resonance venography; SSS, superior sagittal sinus; CVO, cerebral venous occlusion; CVT, cerebral venous thrombosis; DSA, digital subtraction angiography; CT, computed tomography; CTV, computed tomography venography; CVST ...

  19. Association between type of cerebral palsy and the cognitive levels

    Directory of Open Access Journals (Sweden)

    Ratna Dewi Kusumaningrum

    2009-07-01

    Conclusion Our data showed that most patients with cerebral palsy had mental retardation of several cognitive level but there was no significant association between each type of cerebral palsy with cognitive levels.

  20. Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux

    NARCIS (Netherlands)

    F. Grüne (Frank); S. Kazmaier (Stephan); B. Sonntag (Barbara); R.J. Stolker (Robert); A. Weyland (Andreas)

    2014-01-01

    textabstractBACKGROUND:: Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair

  1. Cerebral vascular effects of hypovolemia and dopamine infusions

    DEFF Research Database (Denmark)

    Holst Hahn, Gitte; Heiring, Christian; Pryds, Ole

    2012-01-01

    Despite widespread use, effects of volume boluses and dopamine in hypotensive newborn infants remain controversial. We aimed to elucidate if hypovolemia alone impairs cerebral autoregulation (CA) and if dopamine affects cerebral vasculature....

  2. Effects of exercise in people with cerebral palsy. A review

    National Research Council Canada - National Science Library

    Priego J I Quesada; A G Lucas-Cuevas; S Llana-Belloch; P Pérez-Soriano

    2014-01-01

    .... Literature aiming to improve the quality of life of patients suffering from cerebral pathologies, such as cerebral palsy has observed that both strength and aerobic training lead to significant...

  3. Cerebral near infrared spectroscopy oximetry in extremely preterm infants

    DEFF Research Database (Denmark)

    Hyttel-Sørensen, Simon; Pellicer, Adelina; Alderliesten, Thomas

    2015-01-01

    OBJECTIVE: To determine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants monitored by cerebral near infrared spectroscopy (NIRS) oximetry. DESIGN: Phase II randomised, single blinded, parallel clinical trial. SETTING: Eight tertiary neonatal intensive care units...

  4. [Cerebral actinomycosis pseudotumor: a case report].

    Science.gov (United States)

    Battikh, R; M'Sadek, F; Bougrine, F; Madhi, W; Ben Abdelhafidh, N; Bouziani, A; Yedeas, M; Othmani, S

    2011-03-01

    Cerebral actinomycosis is rare and difficult to diagnose. We report a case of a 45-year-old man hospitalized for seizures associated with fever and left hemiparesis. The white cell count and C-reactive protein were elevated. HIV serology was negative. Blood cultures remained sterile. The CT scan revealed hyperdense nodular lesions in the occipital area, with annular contrast uptake and peripheral edema causing a mass effect, suggestive of brain metastasis. The pathology examination of a surgical specimen disclosed cerebral actinomycosis. A dental origin of the infection was suspected. Hemiparesis remained after a 12-month antibiotic regimen associated with dental care and short-term corticosteroid therapy. Actinomycosis should be discussed as a possible diagnosis for all cerebral lesions, particularly in patients with a potential dental infection. Histology is required for positive diagnosis. Antibiotic therapy alone is generally sufficient; surgery is often performed for diagnostic purposes. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

  5. Computerized tomographic evaluation of cerebral cysticercosis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bo Young; Lee, Mi Sook; Jeon, Doo Sung; Kim, Hong Soo; Rhee, Hak Song [Precbyterian Medical Center, Chonju (Korea, Republic of)

    1988-08-15

    Cerebral cysticercosis, unfortunately frequent in Korea, is a parastic disease in which man serve as the intermediate host of taenia solium. The larvae have a predilection for the central nervous system and can cause a variety of neurologic symptoms. The authors reviewed 19 cases of surgically proven cerebral cysticercosis and following results were obtained. 1. The most frequent age distribution was 5th and 6th decade and male to female ratio was 14:5. 2. The most frevalent involving site was cerebral parenchyme and following by ventricles. 3. Clinical manifestations were symtom and sign of increased ICP, seizure and focal neurological dificit. 4. It was assumed that computerized tomography was the procedure of choice for the diagnosis of these parasitic brain disease.

  6. Validation of a cerebral palsy register

    DEFF Research Database (Denmark)

    Topp, Monica Wedell; Langhoff-Roos, J; Uldall, P

    1997-01-01

    OBJECTIVES: To analyse completeness and validity of data in the Cerebral Palsy Register in Denmark, 1979-1982. METHODS: Completeness has been assessed by comparing data from The Danish National Patient Register (DNPR) with the cases included in the Cerebral Palsy Register (CPR). Agreement between......, but gestational age was subject to a systematic error, and urinary infections in pregnancy (kappa = 0.43) and placental abruption (kappa = 0.52) were seriously under-reported in the CPR. CONCLUSIONS: Completeness of the Cerebral Palsy Register in Denmark, 1979-1982, has been assessed to maximal 85%, emphasizing...... 12 variables in the CPR and obstetrical medical records has been analysed using kappa-statistics. RESULTS: Of 468 children in the DNPR, only 237 fulfilled the inclusion criteria of the CPR; and 35 (15%) of these cases had not been reported to the CPR. Data agreement was generally good...

  7. Neurociências, neurocultura e autoajuda cerebral

    Directory of Open Access Journals (Sweden)

    Francisco Ortega

    2009-12-01

    Full Text Available Este artigo pretende analisar o fenômeno denominado de neuroascese, ou autoajuda cerebral no contexto do crescente impacto das neurociências e do surgimento da neurocultura e do sujeito cerebral. Para tanto, é importante compreender o âmbito sóciocultural mais amplo no qual a neuroascese se insere e que corresponde ao que vem se chamando de 'cultura somática' ou, mais especificamente, de biossociabilidade. O objetivo do artigo é explorar como uma forma de subjetividade reducionista, o sujeito cerebral, dá lugar à aparição de práticas de si cerebrais, isto é, práticas de como agir sobre o cérebro para maximizar a sua performance, que levam a formação de novas formas de sociabilidade.

  8. Neurociências, neurocultura e autoajuda cerebral

    Directory of Open Access Journals (Sweden)

    Francisco Ortega

    Full Text Available Este artigo pretende analisar o fenômeno denominado de neuroascese, ou autoajuda cerebral no contexto do crescente impacto das neurociências e do surgimento da neurocultura e do sujeito cerebral. Para tanto, é importante compreender o âmbito sóciocultural mais amplo no qual a neuroascese se insere e que corresponde ao que vem se chamando de 'cultura somática' ou, mais especificamente, de biossociabilidade. O objetivo do artigo é explorar como uma forma de subjetividade reducionista, o sujeito cerebral, dá lugar à aparição de práticas de si cerebrais, isto é, práticas de como agir sobre o cérebro para maximizar a sua performance, que levam a formação de novas formas de sociabilidade.

  9. Assessment of the hand in cerebral palsy.

    Science.gov (United States)

    Bhardwaj, Praveen; Sabapathy, S Raja

    2011-05-01

    Cerebral palsy is the musculoskeletal manifestation of a nonprogressive central nervous system lesion that usually occurs due to a perinatal insult to the brain. Though the cerebral insult is static the musculoskeletal pathology is progressive. Some patients with cerebral palsy whose hands are affected can be made better by surgery. The surgical procedures as such are not very technically demanding but the assessment, decision-making, and selecting the procedures for the given patient make this field challenging. When done well, the results are rewarding not only in terms of improvement in hand function but also in appearance and personal hygiene, which leads to better self-image and permits better acceptance in the society. This article focuses on the clinical examination, patient selection, and decision-making while managing these patients.

  10. Ocular manifestations in children with cerebral palsy.

    Science.gov (United States)

    Sasmal, Nirmal Kumar; Maiti, Prasenjit; Mandal, Radhakrishna; Das, Debabrata; Sarkar, Subhra; Sarkar, Piyali; Biswas, Mukul Chandra; Dey, Asim Kumar; Chatterjee, Sanjay

    2011-05-01

    To evaluate the prevalence of ocular abnormalities among children with cerebral palsy, 140 patients with age between 6 months and 16 years were selected and the overall incidence of ocular abnormalities in this study was 42.1%. Two major ocular abnormalities identified in these cases were strabismus in 36.4%. Myopia was detected in 12.9% children while hypermetropia in 8.6% and astigmatism in 3.6% cases. Non-glaucomatous optic atrophy was present in 10.7% cases and nystagmus in 9.3% cases. Raised intra-ocular pressure was detected in 2.1% cases. Cortical visual impairment was seen in 20.7% children. Ocular abnormalities are frequent manifestations in cerebral palsy patients. Therefore, evaluation of all cerebral palsy cases emphasises the need for a full ophthalmological examination in order to detect ocular problems and to institute necessary therapy of the abnormalities for better livelihood of these physically challenged patients.

  11. Assessment of the hand in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Praveen Bhardwaj

    2011-01-01

    Full Text Available Cerebral palsy is the musculoskeletal manifestation of a nonprogressive central nervous system lesion that usually occurs due to a perinatal insult to the brain. Though the cerebral insult is static the musculoskeletal pathology is progressive. Some patients with cerebral palsy whose hands are affected can be made better by surgery. The surgical procedures as such are not very technically demanding but the assessment, decision-making, and selecting the procedures for the given patient make this field challenging. When done well, the results are rewarding not only in terms of improvement in hand function but also in appearance and personal hygiene, which leads to better self-image and permits better acceptance in the society. This article focuses on the clinical examination, patient selection, and decision-making while managing these patients.

  12. Training model for cerebral aneurysm clipping

    Directory of Open Access Journals (Sweden)

    Hiroshi Tenjin, M.D., Ph.D.

    2017-12-01

    Full Text Available Clipping of cerebral aneurysms is still an important skill in neurosurgery. We have made a training model for the clipping of cerebral aneurysms. The concepts for the model were 1: training model for beginners, 2: three dimensional manipulation using an operating microscope, 3: the aneurysm model is to be perfused by simulated blood causing premature rupture. The correct relationship between each tissue, and softness of the brain and vessels were characteristics of the model. The skull, brain, arteries, and veins were made using a 3D printer with data from DICOM. The brain and vessels were made from polyvinyl alcohol (PVA. One training course was held and this model was useful for training of cerebral aneurysm surgery for young neurosurgeons.

  13. Contrast MR imaging of acute cerebral infarction

    Energy Technology Data Exchange (ETDEWEB)

    Kogame, Saeko; Syakudo, Miyuki; Inoue, Yuichi (Osaka City Univ. (Japan). Faculty of Medicine) (and others)

    1992-04-01

    Thirty patients with acute and subacute cerebral infarction (13 and 17 deep cerebral infarction) were studied with 0.5 T MR unit before and after intravenous injection of Gd-DTPA. Thirteen patients were studied within 7 days after neurological ictus, 17 patients were studied between 7 and 14 days. Two types of abnormal enhancement, cortical arterial and parenchymal enhancement, were noted. The former was seen in 3 of 4 cases of very acute cortical infarction within 4 days after clinical ictus. The latter was detected in all 7 cases of cortical infarction after the 6th day of the ictus, and one patient with deep cerebral infarction at the 12th day of the ictus. Gd-DTPA enhanced MR imaging seems to detect gyral enhancement earlier compared with contrast CT, and depict intra-arterial sluggish flow which was not expected to see on contrast CT scans. (author).

  14. Sleep Slow-Wave Activity Regulates Cerebral Glycolytic Metabolism

    OpenAIRE

    Wisor, Jonathan P; Rempe, Michael J; Schmidt, Michelle A.; Moore, Michele E.; Clegern, William C.

    2012-01-01

    Non-rapid eye movement sleep (NREMS) onset is characterized by a reduction in cerebral metabolism and an increase in slow waves, 1–4-Hz oscillations between relatively depolarized and hyperpolarized states in the cerebral cortex. The metabolic consequences of slow-wave activity (SWA) at the cellular level remain uncertain. We sought to determine whether SWA modulates the rate of glycolysis within the cerebral cortex. The real-time measurement of lactate concentration in the mouse cerebral cor...

  15. Normal cerebral FDG uptake during childhood

    Energy Technology Data Exchange (ETDEWEB)

    London, Kevin [The Children' s Hospital at Westmead, Department of Nuclear Medicine, Sydney, NSW (Australia); University of Sydney, Discipline of Paediatrics and Child Health, Sydney Medical School, Sydney, NSW (Australia); Howman-Giles, Robert [The Children' s Hospital at Westmead, Department of Nuclear Medicine, Sydney, NSW (Australia); University of Sydney, Disciplines of Imaging and Paediatrics and Child Health, Sydney Medical School, Sydney, NSW (Australia)

    2014-04-15

    Current understanding of cerebral FDG uptake during childhood originates from a small number of studies in patients with neurological abnormalities. Our aim was to describe cerebral FDG uptake in a dataset of FDG PET scans in children more likely to represent a normal population. We reviewed cerebral FDG PET scans in children up to 16 years of age with suspected/proven extracranial malignancies and the following exclusions: central nervous system metastases, previous malignancies, previous chemotherapy or radiotherapy, development of cerebral metastases during therapy, neurological conditions, taking antiepileptic medication or medications likely to interfere with cerebral metabolism, and general anaesthesia within 24 h. White matter, basal ganglia, thalamus and the cerebellar cortex were analysed using regional SUV{sub max}, and the cerebral cortex, basal ganglia, thalamus and cerebellum were analysed using a regional relative uptake analysis in comparison to maximal cortical uptake. Scans from 30 patients (age range 11 months to 16 years, mean age 10 years 5 months) were included. All regions showed increasing SUV{sub max} with age. The parietal, occipital, lateral temporal and medial temporal lobes showed lower rates of increasing FDG uptake causing changing patterns of regional FDG uptake during childhood. The cortical regions showing the most intense uptake in early childhood were the parietal and occipital lobes. At approximately 7 years of age these regions had relatively less uptake than the frontal lobes and at approximately 10 years of age these regions had relatively less uptake than the thalamus. Relative FDG uptake in the brain has not reached an adult pattern by 1 year of age, but continues to change up to 16 years of age. The changing pattern is due to different regional rates of increasing cortical FDG uptake, which is less rapid in the parietal, occipital and temporal lobes than in the frontal lobes. (orig.)

  16. Actividad cerebral y deporte : un estudio mediante mapas de actividad eléctrica cerebral

    OpenAIRE

    Miguel?Tobal, Francisco

    2012-01-01

    Esta tesis trata de conocer las teorías sobre la asimetría cerebral y sus implicaciones en el ámbito deportivo. Para ello se ha utilizado un equipo de cartografía cerebral con registro de EEG y potenciales evocados, intentando demostrar si existen o no variaciones del electroencefalograma en cuanto a actividad cerebral se refiere y variaciones de actividad cortical en cuanto a la amplitud del P300 en cada uno de los grupos. Los grupos utilizados han sido cuatro: sedentarios (diestros y zurdos...

  17. Angiopatia amilóide cerebral simulando tumor cerebral: relato de caso

    OpenAIRE

    Andrade Gustavo Cardoso de; Silveira Roberto Leal; Pinheiro Jr. Nilson; Rocha Eckstânio Marcos Melo; Pittella José Eymard Homem

    2006-01-01

    Descrevemos o raro caso de um paciente de 45 anos portador de lesão expansiva intracraniana por angiopatia amilóide cerebral com características clínicas e de imagem compatíveis com um glioma de baixo grau. A biópsia revelou angiopatia amilóide cerebral. Os achados clínicos, radiológicos e histopatológicos são discutidos e analisados juntamente à literatura disponível.We describe the unusual case of a 45-year-old male patient harboring an intracranial mass due to cerebral amyloid angiopathy w...

  18. Modulation of cerebral blood flow with transcutaneous electrical neurostimulation (TENS) in patients with cerebral vasospasm after subarachnoid hemorrhage

    NARCIS (Netherlands)

    ter Laan, Mark; van Dijk, J.M.C.; Stewart, Roy; Staal, Michiel J; Elting, Jan-Willem J.

    ObjectivesTranscutaneous electrical neurostimulation (TENS) and spinal cord stimulation have been shown to increase peripheral and cerebral blood flow. We postulate that certain pathological conditions attenuate cerebral autoregulation, which may result in a relative increase of the importance of

  19. Radiologic manifestations of focal cerebral hyperemia in acute stroke

    DEFF Research Database (Denmark)

    Olsen, Tom Skyhøj; Skriver, E B; Herning, M

    1991-01-01

    In 16 acute stroke patients with focal cerebral hyperemia angiography and regional cerebral blood flow (rCBF) were studied 1 to 4 days post stroke. CT was performed twice with and without contrast enhancement 3 +/- 1 days and 16 +/- 4 days post stroke. Angiographic evidence of focal cerebral hype...

  20. Auditory Selective Attention in Cerebral-Palsied Individuals.

    Science.gov (United States)

    Laraway, Lee Ann

    1985-01-01

    To examine differences between auditory selective attention abilities of normal and cerebral-palsied individuals, 23 cerebral-palsied and 23 normal subjects (5-21) were asked to repeat a series of 30 items in presence of intermittent white noise. Results indicated that cerebral-palsied individuals perform significantly more poorly when the…

  1. MRI findings and differential diagnosis in children with cerebral paragonimiasis

    Directory of Open Access Journals (Sweden)

    Zhen Zeng

    2016-06-01

    Conclusions: The clinical manifestations of cerebral paragonimiasis are nonspecific in children while the MRI findings of cerebral paragonimiasis are characteristic, including irregular hemorrhage, ring-like enhancement and disproportionately large areas of surrounding edema. Brain MRI plays an important role in the diagnosis of cerebral paragonimiasis in children.

  2. Exogenous glucocorticoids and adverse cerebral effects in children

    DEFF Research Database (Denmark)

    Damsted, Sara K.; Born, A P; Paulson, Olaf B

    2011-01-01

    reduces neurogenesis and cerebral volume, impairs memory and increases the incidence of cerebral palsy. Cerebral effects of glucocorticoids in later childhood have been less thoroughly studied, but apparent brain atrophy, reduced size of limbic structures and neuropsychiatric symptoms have been reported...

  3. Recirculation usually precedes malignant edema in middle cerebral artery infarcts

    DEFF Research Database (Denmark)

    Nielsen, T H; Ståhl, N; Schalén, W

    2012-01-01

    In patients with large middle cerebral artery (MCA) infarcts, maximum brain swelling leading to cerebral herniation and death usually occurs 2-5 days after onset of stroke. The study aimed at exploring the pattern of compounds related to cerebral energy metabolism in infarcted brain tissue....

  4. Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux

    OpenAIRE

    Grüne, Frank; Kazmaier, Stephan; Sonntag, Barbara; Stolker, Robert; Weyland, Andreas

    2014-01-01

    textabstractBACKGROUND:: Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair cerebral aerobic metabolism in patients undergoing intravenous anesthesia. METHODS:: Thirty male patients scheduled for coronary surgery were included in a prospective, controlled crossover trial. Mea...

  5. Profile of Children with Cerebral Palsy Attending Out- patient ...

    African Journals Online (AJOL)

    Olusola Ayanniyi

    Cerebral palsy (CP) is a major cause of childhood disability. The objective of this study was to investigate the causes ... KEY WORDS: cerebral palsy, jaundice, asphyxia, infections, childhood disabilities. INTRODUCTION. Cerebral palsy (CP) is an ...... The effects of multiple pre- and perinatal risk factors on the occurrence of ...

  6. Reversible cerebral vasconstriction syndrome: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Sub; Park, Ji Kang; Kim, Seung Hyoung; Jeong, Sun Young [Jeju National University Hospital, Jeju National University School of Medicine, Jeju (Korea, Republic of)

    2013-11-15

    We report a 46-year-old woman patient with reversible cerebral vasoconstriction syndrome (RCVS). She presented with severe headache, multiple cerebral infarction, and multifocal severe stenosis in the intracranial arteries on magnetic resonance angiography (MRA). One month after the episode, a small bowel gastrointestinal stromal tumor (GIST) was incidentally detected during the evaluation of severe anemia and GIST was removed. Follow-up MRA was performed 3 months and 1 year after an initial attack of headache, and multifocal severe intracranial arterial stenotic lesions were completely resolved, she did not experience any episode of RCVS during the 2 years.

  7. Body image in adolescents with cerebral palsy.

    Science.gov (United States)

    Hammar, Görel Råsmark; Ozolins, Andrejs; Idvall, Ewa; Rudebeck, Carl Edward

    2009-03-01

    The study aims to describe important features of body image in adolescents with motor disabilities and compare them against similar features in able-bodied peers. Relational aspects of body image were given preference in a questionnaire distributed to 35 adolescents with cerebral palsy and 98 adolescents with no known disabilities. Similarities were shown, but also significant differences, indicating a less favourable body image in adolescents with cerebral palsy. It is paramount for young people who are constantly reminded of physical restrictions to experience body vitality. Professionals need to consider the importance of how they interact with young people when seeking to promote a positive body image.

  8. Dihydralazine induces marked cerebral vasodilation in man

    DEFF Research Database (Denmark)

    Schroeder, T; Sillesen, H

    1987-01-01

    Dihydralazine is widely used for acute control of hypertension. In experimental studies it seems to dilate cerebral resistance vessels and increase intracranial pressure. However, the effect on cerebral blood flow (CBF) in man has been little studied. Measurements of CBF were performed with the i...... of dihydralazine was of the same order of magnitude as the effect of 5% CO2 inhalation. These results in normal subjects should be extrapolated to diseased persons only with extreme caution. Still, the very marked and long lasting vasodilation observed suggests that dihydralazine, from a theoretical point of view...

  9. Cerebral infarction and ventricular septal defect.

    Science.gov (United States)

    Shuiab, A

    1989-07-01

    With the availability of contrast echocardiography, patent foramen ovale is frequently detected in patients with stroke, especially in those with no clear etiology and/or the young patient with stroke. Before this report, an association of stroke with ventricular septal defect had not been reported. In this communication, we describe a 38-year-old patient who developed an occipital lobe infarction and who, on investigation, was found to have a ventricular septal defect. Other investigations, which included four-vessel cerebral angiography, collagen disease workup, and coagulation profile, were all normal. We believe this case further extends the spectrum of cerebral ischemic events that may occur with intracardiac shunts.

  10. Transcranial Doppler ultrasound for cerebral perfusion.

    Science.gov (United States)

    Jørgensen, L G

    1995-01-01

    By providing a non-invasive method for continuous display of mean flow velocity (Vmean) in the cerebral arteries, transcranial Doppler (TCD) ultrasound supplements evaluation of cerebral perfusion. Dynamic exercise increases middle cerebral artery (MCA) Vmean from approximately 55 to 65 cm s-1 dependent on work rate, and even more when corrected for changes of the arterial carbon dioxide tension. Evaluation of Vmean corresponds to that of cerebral blood flow as determined with the 133Xenon clearance technique, and reflects regional cortical regulation of the active muscles with important afferent nervous influence. Concomitant increases of mean arterial pressure (MAP) and heart rate is only of minor importance as illustrated during static exercise and post-exercise muscle ischaemia, where Vmean is not significantly elevated. During sustained head-up tilt, the Vmean remained unchanged at a MAP approximately 83 mmHg. Below this level, it decreased in parallel with MAP until MAP reached 50 mmHg. At an even lower MAP, Vmean seemed to approach a lower limit approximately 25 cm s-1, but at a diastolic pressure of 21 mmHg there was no flow in the MCA. Conversely, during post-exercise muscle ischemia, an increase in MAP to 140 mmHg did not influence Vmean. This is in contrast to patients operated for carotid artery stenosis and who develop ipsilateral headache. In these patients the ipsilateral MCA Vmean changed in parallel with MAP, and autoregulation was re-established only after one to two weeks. In patients with severe carotid stenosis and poor collateral circulation, the CO2-reactivity as expressed by Vmean was the lowest, and could be negative on the ipsilateral side. During carotid endarterectomy, a Vmean clamp/Vmean pre-clamp ratio below 0.6 identified patients with a cerebral blood flow below 20 ml 100 g-1 min-1. Furthermore, when the ratio was below 0.4 pathological electroenchephalographic changes developed. Thus, Vmean of the large basal cerebral arteries

  11. Transfer function analysis for the assessment of cerebral autoregulation using spontaneous oscillations in blood pressure and cerebral blood flow

    NARCIS (Netherlands)

    van den Abeelen, Aisha; Beek, Arenda H.E.A.; Slump, Cornelis H.; Panerai, Ronney B.; Claassen, Jurgen A.H.R.

    2014-01-01

    Cerebral autoregulation (CA) is a key mechanism to protect the brain against excessive fluctuations in blood pressure (BP) and maintain cerebral blood flow. Analyzing the relationship between spontaneous BP and cerebral blood flow velocity (CBFV) using transfer function analysis is a widely used

  12. Candidate genes and cerebral palsy: a population-based study.

    Science.gov (United States)

    Gibson, Catherine S; Maclennan, Alastair H; Dekker, Gustaaf A; Goldwater, Paul N; Sullivan, Thomas R; Munroe, David J; Tsang, Shirley; Stewart, Claudia; Nelson, Karin B

    2008-11-01

    The objective of this study was to examine whether selected genetic polymorphisms in the infant are associated with later-diagnosed cerebral palsy. A population-based case-control study was conducted of 28 single-nucleotide polymorphisms measured in newborn screening blood spots. A total of 413 children with later-diagnosed cerebral palsy were born to white women in South Australia in 1986-1999, and there were 856 control children. Distributions of genotypic frequencies were examined in total cerebral palsy, in gestational age groups, and by types of cerebral palsy and gender. Genotyping was performed by using a TaqMan assay. For inducible nitric-oxide synthase, possession of the T allele was more common in all children with cerebral palsy and for heterozygotes who were born at term. For lymphotoxin alpha, homozygous variant status was associated with risk for cerebral palsy and with spastic hemiplegic or quadriplegic cerebral palsy. Among term infants, heterozygosity for the endothelial protein C receptor single-nucleotide polymorphism was more frequent in children with cerebral palsy. In preterm infants, the variant A allele of interleukin 8 and heterozygosity for the beta-2 adrenergic receptor were associated with cerebral palsy risk. Interleukin 8 heterozygote status was associated with spastic diplegia. Variants of several genes were associated with cerebral palsy in girls but not in boys. Two of the 28 single-nucleotide polymorphisms examined were associated with all types of spastic cerebral palsy in both gestational age groups and others with cerebral palsy in gestational age or cerebral palsy subgroups. Some of these associations support previous findings. There may be a genetic contribution to cerebral palsy risk, and additional investigation is warranted of genes and gene-environment interactions in cerebral palsy.

  13. Anastomosis between accessory middle cerebral artery and middle cerebral artery diagnosed by magnetic resonance angiography.

    Science.gov (United States)

    Takahashi, Masao; Uchino, Akira; Suzuki, Chihiro

    2017-06-01

    The accessory middle cerebral artery (MCA) is a common variation of the MCA that arises from the anterior cerebral artery. We report a patient with anastomosis of the accessory MCA with the main MCA, an extremely rare variant that we diagnosed by magnetic resonance (MR) angiography. Both partial maximum-intensity-projection and partial volume-rendering MR angiographic images obtained at 3 T are useful to identify such rare vascular variation.

  14. Hyperdense lesions in CT of cerebral toxoplasmosis. Lesiones hiperdensas en TC en la toxoplamosis cerebral

    Energy Technology Data Exchange (ETDEWEB)

    Quiones Tapia, D.; Ramos Amador, A.; Monereo Alonso, A.

    1994-01-01

    We report a case of cerebral toxoplasmosis in a patient with stage IV C[sub 1] AIDS who presented hyperdense CT images 13 days after beginning antitoxoplasma treatment. These lesions could be caused by calcifications or blood. The attenuation values lead us to believe that they are calcium. Intracranial calcification in adult cerebral toxoplasmosis is an uncommon finding. Its presence in AIDS patients should not suggest any etiology other than toxoplasmosis. (Author) 16 refs.

  15. [Retrospect of the history of cerebral palsy cognition].

    Science.gov (United States)

    Chen, Shao-jun; Wang, Xiu-li

    2008-07-01

    Throughout the cognition history of cerebral palsy, though these literature and art works related to the description of cerebral palsy, yet it only shows that it was an "old disease". The real initiative medical study of cerebral palsy started at mid 19th century. In the mid to late 19th century, Little, Osler, and Freud, the three scholars, perfected the denomination of cerebral palsy, the brain-derived concept, pathogenic classification, diverse clinical characteristics of dyskinesia--oriented manifestations, thus established the basic framework for the study of cerebral palsy.

  16. Monitoring cerebral tissue oxygen saturation during surgery: a clinician's perspective

    Science.gov (United States)

    Meng, Lingzhong; Gelb, Adrian W.; Cerussi, Albert E.; Mantulin, William W.; Tromberg, Bruce J.

    2013-03-01

    Organ protection and physiology optimization are important goals when taking care of anesthetized patients undergoing surgery. Postoperative cognitive dysfunction and perioperative stroke are unwarranted potential outcomes. Neurovascular coupling, the match between cerebral metabolic demand and substrate supply, should be regarded as the essential cerebral physiology which needs to be monitored during surgery. The brain-targeting near-infrared spectroscopy (NIRS) technology has the potential to fulfill this goal. Proposition of why and how to monitor essential cerebral physiology via advanced NIRS technologies is discussed. We also discussed the limits of the current NIRS technologies which merely measure cerebral tissue oxygen saturation in pooled cerebral arterial, capillary, and venous blood.

  17. ORIGINAL ARTICLES Selective cerebral hypothermia for post ...

    African Journals Online (AJOL)

    Selective cerebral hypothermia for post-hypoxic neuroprotection in neonates using a solid ice cap. A R Horn, D L Woods, C Thompson, I Els, M Kroon. Objective. The main objective of this study was to study .the safety and efficacy of a simple, cost-effective method of selective head cooling with mild systemic hypothermia in.

  18. Epilepsy in children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Bruck Isac

    2001-01-01

    Full Text Available OBJECTIVE: To describe the prevalence and characteristics of epilepsy in patients with cerebral palsy in a tertiary center. METHODS: a total of 100 consecutive patients with cerebral palsy were retrospectively studied. Criteria for inclusion were follow-up period for at least 2 years. Types and incidence of epilepsy were correlated with the different forms of cerebral palsy. Other factors associated with epilepsy such as age of first seizure, neonatal seizures and family history of epilepsy were also analysed. RESULTS: follow-up ranged between 24 and 151 months (mean 57 months. The overall prevalence of epilepsy was 62%. Incidence of epilepsy was predominant in patients with hemiplegic and tetraplegic palsies: 70.6% and 66.1%, respectively. First seizure occurred during the first year of life in 74.2% of patients with epilepsy. Generalized and partial were the predominant types of epilepsy (61.3% and 27.4%, respectively. Thirty-three (53.2% of 62 patients were seizure free for at least 1 year. Neonatal seizures and family history of epilepsy were associated with a higher incidence of epilepsy. CONCLUSIONS: epilepsy in cerebral palsy can be predicted if seizures occur in the first year of life, in neonatal period and if there is family history of epilepsy.

  19. Cerebral Malaria Complicated by Blindness, Deafness and ...

    African Journals Online (AJOL)

    Malaria is a parasitic disease affecting about 1 billion people globally and causing about 1.24 million deaths ... its attendant sequelae such as cerebral palsy, cortical blindness, sensory-neural deafness and rarely ... under pressure, and its analysis and culture were normal. Blood film for malaria parasite was positive for ...

  20. Cerebral asymmetries: complementary and independent processes.

    Directory of Open Access Journals (Sweden)

    Gjurgjica Badzakova-Trajkov

    Full Text Available Most people are right-handed and left-cerebrally dominant for speech, leading historically to the general notion of left-hemispheric dominance, and more recently to genetic models proposing a single lateralizing gene. This hypothetical gene can account for higher incidence of right-handers in those with left cerebral dominance for speech. It remains unclear how this dominance relates to the right-cerebral dominance for some nonverbal functions such as spatial or emotional processing. Here we use functional magnetic resonance imaging with a sample of 155 subjects to measure asymmetrical activation induced by speech production in the frontal lobes, by face processing in the temporal lobes, and by spatial processing in the parietal lobes. Left-frontal, right-temporal, and right-parietal dominance were all intercorrelated, suggesting that right-cerebral biases may be at least in part complementary to the left-hemispheric dominance for language. However, handedness and parietal asymmetry for spatial processing were uncorrelated, implying independent lateralizing processes, one producing a leftward bias most closely associated with handedness, and the other a rightward bias most closely associated with spatial attention.

  1. Occupational therapy for children with cerebral palsy.

    NARCIS (Netherlands)

    Steultjens, E.M.J.; Dekker, J.; Bouter, L.M.; Nes, J.C.M. van de; Lambregts, B.L.M.; Ende, C.H.M. van den

    2003-01-01

    Objectives: The object of our systematic review, therefore, was to determine whether OT interventions improve functional abilities and social participation in children with cerebral palsy. Criteria for considering Studies for this Review: Types of studies: Studies with one of the following designs

  2. Pulsatile flow in model cerebral aneurysms

    NARCIS (Netherlands)

    Mikhal, Julia Olegivna; Geurts, Bernardus J.; Sato, Mitsuhisa; Matsuoka, Satoshi; Sloot, Peter M.; van Albada, G. Dick; Dongarra, Jack

    2011-01-01

    We present an immersed boundary method based on volume penalization, with which pulsatile flow in a model cerebral aneurysm is simulated. The model aneurysm consists of a curved vessel merged with a spherical cavity. The dominant vortical structures arising in the time-dependent flow are discussed

  3. Spontaneous peripheral gangrene following severe cerebral malaria

    African Journals Online (AJOL)

    She gave a history of sudden onset of a severe febrile illness during July 1998, nine weeks prior to her arrival in Addis Ababa. She had attended her local local Health Centre where she had been admitted and treated for cerebral malaria. Unfortunately, no records of the laboratory findings or treatment given were available.

  4. [Cerebral infarction in human immunodeficiency virus infection].

    Science.gov (United States)

    Blanche, P; Toulon, P; de La Blanchardière, A; Sicard, D

    1995-06-03

    Patients infected with the human immunodeficiency virus (HIV) appear to have a high risk of ischaemic cerebral events. We observed two cases of cerebral infarction in patients with acquired immune deficiency syndrome (AIDS). In the first case, a 38-year-old homosexual with no cardiovascular risk other than smoking presented with rapidly progressive hemiparesia. Brain CT-scan visualized two infarcts in the territory of the right sylvian artery and the arteriography an occlusion of the internal carotid artery. In the second, a 37-year-old homosexual, hospitalization was required for a left-sided pure sensitive epilepsy seizure. There was no cardiovascular risk other than smoking. Magnetic resonance imaging showed parietal ischaemia and thrombus in the left atrium without atrial hypertrophy was seen at transoesophageal echocardiography. In both cases, there was no evidence of endocarditis, dissection of the neck vessels or disseminated intravascular coagulation nor of associated viral or bacterial infectious complication of AIDS. Angiographic findings eliminated cerebral vascularitis. Among the perturbed haemostasis factors previously reported in HIV+ patients, we observed free proteins S deficiency (68 and 43%) and heparin cofactor II deficiency (54 and 40%). Serum albumin was 33 and 32 g/l respectively. Outcome was favourable in both cases with anticoagulant therapy. These coagulation anomalies would not appear sufficient to explain cerebral infarction. Other mechanisms including immune complexed deposition, direct HIV toxicity for endothelial cells or the effect of cytokines on smooth muscles fibres and fibroblasts are probably more important causal factors.

  5. Cerebral Arterial Thrombosis in Ulcerative Colitis

    Directory of Open Access Journals (Sweden)

    Giovanni Casella

    2013-01-01

    Full Text Available Thrombosis, mainly venous, is a rare and well-recognized extraintestinal manifestation of inflammatory bowel disease (IBD. We describe a 25-year-old Caucasian man affected by ulcerative colitis and sclerosing cholangitis with an episode of right middle cerebral arterial thrombosis resolved by intraarterial thrombolysis. We perform a brief review of the International Literature.

  6. Cerebral arterial thrombosis in ulcerative colitis.

    Science.gov (United States)

    Casella, Giovanni; Cortelezzi, Claudio Camillo; Marialuisa, Delodovici; Cariddi Lucia, Princiotta; Elena Pinuccia, Verrengia; Baldini, Vittorio; Segato, Sergio

    2013-01-01

    Thrombosis, mainly venous, is a rare and well-recognized extraintestinal manifestation of inflammatory bowel disease (IBD). We describe a 25-year-old Caucasian man affected by ulcerative colitis and sclerosing cholangitis with an episode of right middle cerebral arterial thrombosis resolved by intraarterial thrombolysis. We perform a brief review of the International Literature.

  7. Cerebral energy metabolism during induced mitochondrial dysfunction

    DEFF Research Database (Denmark)

    Nielsen, T H; Bindslev, TT; Pedersen, S M

    2013-01-01

    In patients with traumatic brain injury as well as stroke, impaired cerebral oxidative energy metabolism may be an important factor contributing to the ultimate degree of tissue damage. We hypothesize that mitochondrial dysfunction can be diagnosed bedside by comparing the simultaneous changes in...

  8. Epidemiology of Cerebral Palsy in the Netherlands

    NARCIS (Netherlands)

    M.J. Wichers (Marc Jan)

    2011-01-01

    textabstractChildren with cerebral palsy (CP) and their families often make strong demands on diagnostic, therapeutic, technical and social facilities. Prevalence estimates are needed to improve treatment and services. As recent Dutch data are not available, the present study aimed to assess the

  9. Pretend Play of Children with Cerebral Palsy

    Science.gov (United States)

    Pfeifer, Luzia Iara; Pacciulio, Amanda Mota; dos Santos, Camila Abrao; dos Santos, Jair Licio; Stagnitti, Karen Ellen

    2011-01-01

    Background and Purpose: Evaluate self-initiated pretend play of children with cerebral palsy. Method: Twenty preschool children participated in the study. Pretend play ability was measured by using the child-initiated pretend play assessment culturally adapted to Brazil. Results: There were significant negative correlations between the children's…

  10. Parental infertility and cerebral palsy in children

    DEFF Research Database (Denmark)

    Zhu, Jin Liang; Hvidtjørn, Dorte; Basso, Olga

    2010-01-01

    Children born after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) have been reported to have a higher risk of cerebral palsy (CP), perhaps due to the higher frequency of preterm birth, multiple births or vanishing embryo in the pregnancies. However, it has been suggested...

  11. Gait Stability in Children with Cerebral Palsy

    Science.gov (United States)

    Bruijn, Sjoerd M.; Millard, Matthew; van Gestel, Leen; Meyns, Pieter; Jonkers, Ilse; Desloovere, Kaat

    2013-01-01

    Children with unilateral Cerebral Palsy (CP) have several gait impairments, amongst which impaired gait stability may be one. We tested whether a newly developed stability measure (the foot placement estimator, FPE) which does not require long data series, can be used to asses gait stability in typically developing (TD) children as well as…

  12. Educational Solutions for Children with Cerebral Palsy

    Science.gov (United States)

    Driver, Lynn; Omichinski, Donna Riccio; Miller, Nicole; Sandella, Danielle; Warschausky, Seth

    2010-01-01

    This paper characterizes educational strengths and needs of children with cerebral palsy (CP) and connects research findings from the University of Michigan's Adapted Cognitive Assessment Lab (ACAL) to current special educational requirements. It acknowledges the uniqueness of educating a child with significant motor and communication disabilities…

  13. Narrative Ability in Children with Cerebral Palsy

    Science.gov (United States)

    Holck, Pernille; Sandberg, Annika Dahlgren; Nettelbladt, Ulrika

    2011-01-01

    In a previous study a group of children with cerebral palsy (CP) were found to have considerable difficulties with narratives, performing several standard deviations below the criteria for the Information score of the Bus Story Test (BST). To examine in depth the performance of children with CP and a control group with typically developing (TD)…

  14. Surgical treatment of cerebral cavernous malformations.

    Science.gov (United States)

    Davies, J M; Kim, H; Lawton, M T

    2015-09-01

    Cerebral cavernous malformations (CMs) are clusters of abnormally-formed, thin-walled blood vessels that tend to hemorrhage, resulting in focal neurological deficits, seizures, and even death, depending on the location of the lesion and extent of bleeding. Management of cerebral CMs can be reduced to the decision to observe or to surgically resect. The objective of the paper was to review options for surgical management of cerebral CMs. A university-based CM practice was examined for: 1) anatomical distribution of operatively managed CMs; and 2) surgical approaches to eloquent CMs. Although cerebral CMs can occur throughout the brain and can lead to significant neurological morbidity, even in highly eloquent locations, such as the brainstem, thalamus, and basal ganglia, experience demonstrates that the majority of CMs can be safely resected and that patients tend to experience long-term improvement in neurological function. The keys to good patient outcomes lie in appropriate patient selection and in thoughtful choice of a surgical approach that minimizes transgression of normal structures.

  15. Natural history of cerebral saccular aneurysms

    African Journals Online (AJOL)

    initial one. Keywords: Natural history, Cerebral saccular aneurysm,. Aneurysmal rupture. Résumé. Anévrysmes cérébrum sacculaires sont assez courant, et le plus souvent situés aux points embranchment des grandes arteres du circle du Willis. Beaucoup sont assymptomatiques et seulement découvert incidemment. Des.

  16. Short communication: Cerebral Malaria Complicated by Blindness ...

    African Journals Online (AJOL)

    Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8‑year‑old boy who presented with high‑grade ...

  17. Cerebral blood flow in acute mountain sickness

    DEFF Research Database (Denmark)

    Jensen, J B; Wright, Anne; Lassen, N A

    1990-01-01

    Changes in cerebral blood flow (CBF) were measured using the radioactive xenon technique and were related to the development of acute mountain sickness (AMS). In 12 subjects, ascending from 150 to 3,475 m, CBF was 24% increased at 24 h [45.1 to 55.9 initial slope index (ISI) units] and 4% increased...

  18. SPECT analysis of recent cerebral infarction

    DEFF Research Database (Denmark)

    Raynaud, C; Rancurel, G; Tzourio, N

    1989-01-01

    We measured regional cerebral blood flow and [123I]iodoamphetamine (IMP) uptake in 16 patients with unilateral brain infarcts during the subacute period (Day 3 to Day 50) and again after 3 months. Our results show that the central and peripheral areas described earlier in the chronic period were ...

  19. ORIGINAL ARTICLES Regional cerebral oxygenation monitoring ...

    African Journals Online (AJOL)

    Intraoperative near—infrared spectroscopy cerebral QXygenatiOn monitoring assists intraoperatiVe ... was continued, including the use of near-infrared spectroscopy. (NIRS) with the Somanetics (Troy, MI, USA) INVOS 5100 .... The INVOS 5100 monitor employs NIRS technology with an infrared light source and two sensors ...

  20. Cerebral Palsy: Still A Social Problem

    Directory of Open Access Journals (Sweden)

    Angom Bisharda

    1997-08-01

    Full Text Available Research Problem: What arc the social aspects of cerebral palsy?Objective: To determine the extent and severity of neuromuscular involvement in cases of cerebral palsy and to find out the associated defects among these children.Study Design: Cross sectional study.Setting: Tertiary care hospital, outdoor patients.Participants: Children in the age group of 0 - 12 years.Sample Size: 120 children suffering from cerebral palsy.Study Variables: Social factors, neuromuscular involvement.Statistical Analysis: By proportionsResult: Out of 120 cases, maximum number of cases (66.6% were in the age group of 1- 4 years. 83 cases ( 69.16% were males. Among the various types, spastic type was the commonest (87.5%. Of these spastic cases, 52 (49.52% had quadriplegia. No case of tremor and rigidity was seen. Delayed milestones was the commonest associated disorder, seen in 107 (89.16% cases, followed by speech defect in 58(48.3% cases, visual defect in 34(28.3% cases and convulsions in 24 (20.0% cases. Hearing defect was seen in 5 cases (4.16% only.Conclusion: More concerted efforts arc required to identify children with cerebral palsy and rehabilitate them for the betterment of society.

  1. Plasticity and function of cerebral lateralization

    NARCIS (Netherlands)

    Lust, J.M.

    2011-01-01

    Lateralization refers to the division of labour between the hemispheres. The studies presented in this thesis addressed the developmental plasticity and function of cerebral lateralization. The access to an unique dataset of prenatal testosterone (pT) levels and the use of fTCD to measure individual

  2. Thromboelastography in patients with cerebral venous thrombosis

    NARCIS (Netherlands)

    Koopman, Karen; Uyttenboogaart, Maarten; Hendriks, Herman G. D.; Luijckx, Gert-Jan; Cramwinckel, Ivo R.; Vroomen, Patrick C.; De Keyser, Jacques; van der Meer, Jan

    Introduction: Cerebral venous thrombosis (CVT) is a rare presentation of venous thrombosis and has been associated with many conditions. In about 20% no risk factor is identified. The aim of this study was to assess the clot formation by thromboelastography (TEG) in patients with a history of CVT

  3. Obstruction of cerebral arteries in childhood stroke

    Energy Technology Data Exchange (ETDEWEB)

    Velkey, I.; Lombay, B. (County Teaching Hospital, Miskolc (Hungary). Child Health Center); Panczel, G. (Semmelweis Medical Univ., Budapest (Hungary). Dept. of Psychiatry)

    1992-09-01

    Middle cerebral artery obstruction in children is reviewed by our two cases. Ischemic childhood stroke was caused by moyamoya disease in the first, and by fibromuscular dysplasia in the second patient. In both cases transcranial Doppler sonography and cranial CT were performed, but the final diagnosis was made by angiography. The importance of angiography in childhood stroke is emphasized. (orig.).

  4. [Cerebral oedema caused by sodium valproate].

    Science.gov (United States)

    Hurri, Lauri; Posti, Jussi; Seppä, Juha Matti; Rauhala, Esa; Puustinen, Juha

    2014-01-01

    Sodium valproate is widely used as an antiepileptic drug. It has potential side effects and its overdosage is toxic. We present a case where a sodium valproate intoxication with severe cerebral oedema was managed in the intensive care unit with hemodialysis, levocarnitine and supportive care.

  5. MANAGEMENT OF CHILDREN WITH CEREBRAL PALSY

    African Journals Online (AJOL)

    Enrique

    The neurological lesion causing cerebral palsy (CP) is static, but the clinical con- dition changes over time. CP has a wide clinical spectrum with a number of aeti- ologies. It is not sufficient just to make the diagnosis of CP; the term needs further qualification by a more detailed description of the clinical condition. There are.

  6. Cerebral hemodynamics in normal and complicated pregnancy

    NARCIS (Netherlands)

    van Veen, Teelkien

    2016-01-01

    During pregnancy, approximately 6-25% of women are diagnosed with some form of hypertension. These disorders are among the leading causes of maternal mortality and severe morbidity. While multiple maternal organs can be affected, cerebral involvement is one of the most feared complications as it can

  7. Treatment of paediatric cerebral palsy with Dysport.

    Science.gov (United States)

    Ubhi, T

    2000-10-01

    Dysport (Clostridium botulinum type A toxin-haemagglutin complex) has had its licence extended to include treatment of children aged 2 years and over with dynamic equinus foot deformity, caused by spasticity associated with cerebral palsy. Dysport reduces muscle tone, thus improving function, relieving pain, and facilitating physiotherapy, application and tolerability of splints.

  8. THE PATHOGENESIS OF CEREBRAL GLIOMATOUS CYSTS

    NARCIS (Netherlands)

    LOHLE, PNM; VERHAGEN, ITHJ; TEELKEN, AW; BLAAUW, EH; GO, KG

    In this study, the authors have examined the mechanism of the formation of tumor cysts. Cyst fluid samples were obtained during surgery and by percutaneous aspiration from 22 patients with cystic cerebral gliomas. The concentration of protein was measured in the cyst fluid and blood plasma. Analysis

  9. Cerebral Palsy. NICHCY Disability Fact Sheet #2

    Science.gov (United States)

    National Dissemination Center for Children with Disabilities, 2010

    2010-01-01

    Cerebral palsy--also known as CP--is a condition caused by injury to the parts of the brain that control the body's ability to use muscles effectively. Often the injury happens before birth, sometimes during delivery or soon after birth. The symptoms will differ from person to person and change as children and their nervous systems mature. This…

  10. Cerebral Malaria Complicated by Blindness, Deafness and ...

    African Journals Online (AJOL)

    Introduction. Malaria is a parasitic disease affecting about 1 billion people globally and causing about 1.24 million deaths annually especially in the developing countries.[1,2] About. 1% of the patients with Plasmodium falciparum develop severe manifestations culminating in multi-organ failure.[3]. Cerebral malaria is one of ...

  11. Mathematical Modelling of Cerebral Blood Circulation and Cerebral Autoregulation: Towards Preventing Intracranial Hemorrhages in Preterm Newborns

    Directory of Open Access Journals (Sweden)

    Renée Lampe

    2014-01-01

    Full Text Available Impaired cerebral autoregulation leads to fluctuations in cerebral blood flow, which can be especially dangerous for immature brain of preterm newborns. In this paper, two mathematical models of cerebral autoregulation are discussed. The first one is an enhancement of a vascular model proposed by Piechnik et al. We extend this model by adding a polynomial dependence of the vascular radius on the arterial blood pressure and adjusting the polynomial coefficients to experimental data to gain the autoregulation behavior. Moreover, the inclusion of a Preisach hysteresis operator, simulating a hysteretic dependence of the cerebral blood flow on the arterial pressure, is tested. The second model couples the blood vessel system model by Piechnik et al. with an ordinary differential equation model of cerebral autoregulation by Ursino and Lodi. An optimal control setting is proposed for a simplified variant of this coupled model. The objective of the control is the maintenance of the autoregulatory function for a wider range of the arterial pressure. The control can be interpreted as the effect of a medicament changing the cerebral blood flow by, for example, dilation of blood vessels. Advanced numerical methods developed by the authors are applied for the numerical treatment of the control problem.

  12. Clinical and pathological study on 10 cases of cerebral lobe hemorrhage related with cerebral amyloid angiopathy

    Directory of Open Access Journals (Sweden)

    Xiao-qi LI

    2015-07-01

    Full Text Available Objective To summarize the clinical data and pathological features of 10 cases of cerebral lobar hemorrhage related with cerebral amyloid angiopathy (CAA diagnosed pathologically, thereby to improve the knowledge and diagnosis of the disease. Methods The clinical data of 10 cases of cerebral lobar hemorrhage related with CAA, collected in the General Hospital of Shenyang Command from 1983 up to now, were retrospectively analyzed, and the clinical and neuropathological features of these cases were summarized. Results Of the 10 patients, 2 suffered from single lobar hemorrhage and 8 multiple lobar hemorrhage, all of them were confirmed pathologically to have ruptured into the subarachnoid space. Pathological examination revealed microaneurysm in 2 cases, "double barrel" change in 4 cases, multiple arteriolar clusters in 5 cases, obliterative onion-liked intima change in 4 cases, and fibrinoid necrosis of vessel wall in 7 cases. In addition, neurofibrillary tangles were found in 8 cases, and senile plaque was observed in 5 cases. Conclusions Cerebral lobar hemorrhage related with CAA is mainly located in the parietal, temporal and occipital lobes, readily breaking into the subarachnoid space, and it is often multiple and recurrent. The CAA associated microvasculopathy was found frequently in the autopsy sample of CAA related cerebral lobar hemorrhage, and it may contribute to the pathogenesis of cerebral hemorrhage. DOI: 10.11855/j.issn.0577-7402.2015.07.04

  13. [Neonatal ultrasonographic cerebral findings: association with risk factor for cerebral palsy].

    Science.gov (United States)

    Staneva, K N; Hartmann, S; Uhlemann, M; Dietze, H; Reschke, E; Koepcke, E; Sadenwasser, W; Külz, Th

    2002-01-01

    Is it possible to identify patients with cerebral palsy (CP) with postnatal ultrasound scan? Which risk factors are associated with an increased risk of CP?. The data of 37 children with CP, who were sonographically investigated during the first 24 hours of life were analyzed retrospectively. The data of 21 preterm infants with gestational age /= 33 wk and in 5/8 of the mature babies. The mature babies had prenatal brain atrophy or hypoxic-ischaemic cerebral lesions. Cytomegaly and encephalitis were detected in two babies. Immature babies >/= 33 wk showed prenatal porencephaly or encephalomalacia after asphyxia. Premature babies cystic periventricular leucomalacia (n=12) or cerebral haemorrhage (n=3); 3 babies had meningitis. Only two prematures cystic periventricular leucomalacia (OR 24,89; 95 % CI: 5,85 - 105,87), cerebral atrophy (OR 4,84; 95 % CI: 1,61 - 14,51), fetal hypoxia (CTG) - (OR 4,78; 95 % CI: 1,31 - 17,45), abruptio placentae (OR 4,32; 95 % CI: 1,16 - 16,13), anemia after birth (OR 18,13; 95 % CI: 1,97 - 166,43), abnormal neurological behavior at term (OR 14,00; 95 % CI: 3,29 - 59,55). Cerebral ultrasound scan after birth is a useful method detect for cerebral lesions in patients with CP-risks.

  14. Cerebral small-resistance artery structure and cerebral blood flow in normotensive subjects and hypertensive patients.

    Science.gov (United States)

    De Ciuceis, Carolina; Cornali, Claudio; Porteri, Enzo; Mardighian, Dikran; Pinardi, Chiara; Fontanella, Marco M; Rodella, Luigi F; Rezzani, Rita; Rizzoni, Damiano; Boari, Gianluca E M; Rosei, Enrico Agabiti; Gasparotti, Roberto

    2014-12-01

    The aim of this study was to prospectively investigate whether the structure of cerebral small-resistance arteries is related to cerebral perfusion parameters as measured with dynamic susceptibility-weighted contrast magnetic resonance imaging (DSC-MRI) in a selected cohort of hypertensive and normotensive patients. Ten hypertensive and 10 normotensive patients were included in the study. All patients underwent neurosurgical intervention for an intracranial tumor and were investigated with DSC-MRI at 1.5 T. Cerebral small-resistance arteries were dissected from a small portion of morphologically normal cerebral tissue and mounted on an isometric myograph for the measurement of the media-to-lumen (M/L) ratio. A quantitative assessment of cerebral blood flow (CBF) and volume (CBV) was performed with a region-of-interest approach. Correlation coefficients were calculated for normally distributed variables. The institutional review board approved the study, and informed consent was obtained from all patients. Compared with normotensive subjects, hypertensive patients had significantly lower regional CBF (mL/100 g/min) in the cortical grey matter (55.63 ± 1.90 vs 58.37 ± 2.19, p cerebral arteries and CBF in the cortical grey matter (r = -0.516, p microvascular structure might play a role in controlling CBF, with possible clinical consequences.

  15. Evaluation of radiation risk and work practices during cerebral interventions

    Energy Technology Data Exchange (ETDEWEB)

    Livingstone, Roshan S; Raghuram, L; Korah, Ipeson P; Raj, D Victor [Department of Radiodiagnosis, Christian Medical College, Vellore 632004 (India)

    2003-09-01

    This study was intended to evaluate radiation risk to patients during cerebral interventions and the contribution to this risk from work practices. Thirty nine patients undergoing cerebral interventions in a digital subtraction angiography suite were included in this study. Patients who underwent cerebral interventions were categorised into two groups according to the number of cerebral interventions performed on them, and their effective doses were calculated. The effective dose for patients undergoing a single cerebral intervention (group A) varied from 1.55 to 15.9 mSv and for multiple cerebral interventions (group B) varied from 16.52 to 43.52 mSv. Two patients who underwent multiple cerebral interventions (group B) had alopecia of the irradiated scalp.

  16. Sialorrhea in children with cerebral palsy.

    Science.gov (United States)

    Dias, Bruno Leonardo Scofano; Fernandes, Alexandre Ribeiro; Maia Filho, Heber de Souza

    To review the literature on sialorrhea in children with cerebral palsy. Non-systematic review using the keywords "sialorrhea" and "child" carried out in the PubMed ® , LILACS ® , and SciELO ® databases during July 2015. A total of 458 articles were obtained, of which 158 were analyzed as they were associated with sialorrhea in children; 70 had content related to sialorrhea in cerebral palsy or the assessment and treatment of sialorrhea in other neurological disorders, which were also assessed. The prevalence of sialorrhea is between 10% and 58% in cerebral palsy and has clinical and social consequences. It is caused by oral motor dysfunction, dysphagia, and intraoral sensitivity disorder. The severity and impact of sialorrhea are assessed through objective or subjective methods. Several types of therapeutic management are described: training of sensory awareness and oral motor skills, drug therapy, botulinum toxin injection, and surgical treatment. The most effective treatment that addresses the cause of sialorrhea in children with cerebral palsy is training of sensory awareness and oral motor skills, performed by a speech therapist. Botulinum toxin injection and the use of anticholinergics have a transient effect and are adjuvant to speech therapy; they should be considered in cases of moderate to severe sialorrhea or respiratory complications. Atropine sulfate is inexpensive and appears to have good clinical response combined with good safety profile. The use of trihexyphenidyl for the treatment of sialorrhea can be considered in dyskinetic forms of cerebral palsy or in selected cases. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  17. Transbrachial artery approach for selective cerebral angiography

    Energy Technology Data Exchange (ETDEWEB)

    Touho, Hajime; Karasawa, Jun; Shishido, Hisashi; Morisako, Toshitaka; Numazawa, Shinichi; Yamada, Keisuke; Nagai, Shigeki; Shibamoto, Kenji (Osaka Neurological Inst., Toyonaka (Japan))

    1990-02-01

    Transaxillary or transbrachial approaches to the cerebral vessels have been reported, but selective angiography of all four vessels has not been possible through one route. In this report, a new technique for selective cerebral angiography with transbrachial approach is described. One hundred and twenty three patients with cerebral infarction, vertebrobasilar insufficiency, intracerebral hemorrhage, epilepsy, or cerebral tumor were examined. Those patients consisted of 85 outpatients and 38 inpatients whose age ranged from 15 years old to 82 years old. The patients were examined via the transbrachial approach (97 cases via the right brachial, 29 cases via the left). Materials included a DSA system (Digital Fluorikon 5000, General Electric Co.), a 4 French tight J-curved Simmons 80-cm catheter, a 19-gauge extra-thin-wall Seldinger needle, and a J/Straight floppy 125-cm guide-wire. Generally, the volume of the contrast agent (300 mgI/ml iopamidol) used in the common carotid artery angiogram was 6 ml, while that used in the vertebral artery angiogram was 4 ml. If catheterization of the vertebral artery or right common carotid artery was unsuccessful, about 8 ml of the contrast agent was injected into the subclavian or branchiocephalic artery. Definitive diagnosis and a decision on proper treatment of the patients can be easily obtained, and the results were clinically satisfactory. Moreover, no complications were encountered in this study. This new technique making a transbrachial approach to the cerebral vessels using the DSA system is introduced here. Neurosurgeons can use this technique easily, and they will find that it provides them with all the information they need about the patient. (author).

  18. Particularites des accidents vasculaires cerebraux au Togo et en ...

    African Journals Online (AJOL)

    Les AVCI prédominent mais le taux des AVCH est très élevé. Il se situe entre 28 et 60%. L'HTA représente le facteur de risque majeur : 68-85%, suivie des cardiopathies et du diabète. Les AVC demeurent une pathologie coûteuse et responsable d'une morbi-mortalité importante. Les publications sur cette pathologie en ...

  19. Facteurs de risque vasculaire predisposant aux lacunes cerebrales ...

    African Journals Online (AJOL)

    Damelan Kombate, Kokou Mensah Guinhouya, Vinyo Kumako, Komi Assogba, Kossivi Apetse, Sylvère Kevi, Rabi Barque, Massahoudou Alla-Sene, Panabalo Waklatsi, Gnininvi Anayo, Mofou Belo, Emile Kous'anta Amouzou, Agnon Ayélola Koffi Balogou, Eric Kodjo Grunitzky ...

  20. Une petite malformation vasculaire provoquée | Elouarradi | Pan ...

    African Journals Online (AJOL)

    Ce type de malformation est influencé par les phénomènes hormonaux, il existe souvent une aggravation au moment de la puberté et lors des grossesses. Une abstention thérapeutique a été proposée chez cette patiente avec surveillance rapprochée au cours de la gestation, vu le risque de saignement. Un traitement ...

  1. Piotr Piotrowski Awangarda w cieniu Jałty. Sztuka w Europie środkowo-wschodniej w latach 1945–89 (Avant-Garde in the Shadow of Yalta. Art in East-Central Europe, 1945–1989 2005.

    Directory of Open Access Journals (Sweden)

    Piotr Bernatowicz

    2007-05-01

    Full Text Available Mieczysław Porębski, a distinguished Polish art historian of the 20th century, once expressed the demand for Polish art history to be researched simultaneously with foreign studies - as parallel fields. "We entered the research field of the old masters' art as partners in, so to say, a ‘furnished household', whereas in the field of contemporary art we are co-explorers, exploring a ‘virgin land'", as Porębski put it. The book by professor Piotr Piotrowski Awangarda w cieniu Jałty. Sztuka w Europie środkowo-wschodniej w latach 1945-89 (The Avant-Garde in the Shadow of Yalta. The Art in East-Central Europe, 1945-1989 fully accomplishes this demanding postulate which nowadays seems to be rather rarely remembered by Polish art historians. The explored area, the East-Central European countries, which emerged, as a result of the Yalta Conference, between the iron curtain and the border of The Soviet Union (including former Yugoslavia appears at least as an ‘old maiden' land, where scientific penetration still seems to be necessary.

  2. La chronologie du royaume de Qatabân du Ier siècle avant J.-C. au Ier siècle après J.-C.

    Directory of Open Access Journals (Sweden)

    Mounir Arbach

    2002-04-01

    Full Text Available Les nouvelles découvertes archéologiques et épigraphiques de ces dernières années, effectuées au cours des fouilles franco-italiennes à Tamna`, l'ancienne capitale du royaume de Qatabân, permettent d'établir une nouvelle chronologie des souverains de Qatabân entre le Ier siècle avant J.-C. et le Ier siècle après J.- C.The chronology of the kingdom of Qatabân, from the 1st century BC to the 1st century AD. Archaeological and epigraphical discoveries made in recent years by the Franco-Italian excavations at Tamna`, the ancient capital of the kingdom of Qatabân, allows us to establish a new chronology for the kings of Qatabân during the 1st century BC and the 1st century AD.

  3. Cholinesterase inhibition improves blood flow in the ischemic cerebral cortex.

    Science.gov (United States)

    Scremin, O U; Li, M G; Scremin, A M; Jenden, D J

    1997-01-01

    The ability of central cholinesterase inhibition to improve cerebral blood flow in the ischemic brain was tested in Sprague-Dawley rats with tandem occlusion of left middle cerebral and common carotid arteries. Cerebral blood flow was measured with lodo- 14C-antipyrine autoradiography in 170 regions of cerebral cortex. The regional distribution of blood flow was characterized in normal animals by cerebral blood flow maxima in the temporal regions. After 2 h ischemia, minimum cerebral blood flow values were found in the lateral frontal and parietal areas on the left hemisphere, and a new maximum was found in the right hemisphere in an area approximately symmetrical to the ischemic focus. Heptyl-physostigmine (eptastigmine), a carbamate cholinesterase inhibitor with prolonged time of action improved cerebral blood flow in most regions, with the exception of the ischemic core. The drug also enhanced the ischemia-induced rostral shift of cerebral blood flow maxima in the right hemisphere. The effects of eptastigmine were more marked 24 h after ischemia. Discriminant analysis showed that data from only 22 regions was sufficient to achieve 100% accuracy in classifying all cases into the various experimental conditions. The redistribution of cerebral blood flow to the sensorimotor area of the right hemisphere of animals with cerebral ischemia, a phenomenon possibly related to recovery of function, was also enhanced by eptastigmine.

  4. Acute Headache at Emergency Department: Reversible Cerebral Vasoconstriction Syndrome Complicated by Subarachnoid Haemorrhage and Cerebral Infarction

    Directory of Open Access Journals (Sweden)

    M. Yger

    2015-01-01

    Full Text Available Introduction. Reversible cerebral vasoconstriction syndrome is becoming widely accepted as a rare cause of both ischemic and haemorrhagic stroke and should be evocated in case of thunderclap headaches associated with stroke. We present the case of a patient with ischemic stroke associated with cortical subarachnoid haemorrhage (cSAH and reversible diffuse arteries narrowing, leading to the diagnosis of reversible vasoconstriction syndrome. Case Report. A 48-year-old woman came to the emergency department because of an unusual thunderclap headache. The computed tomography of the brain completed by CT-angiography was unremarkable. Eleven days later, she was readmitted because of a left hemianopsia. One day after her admission, she developed a sudden left hemiparesis. The brain MRI showed ischemic lesions in the right frontal and occipital lobe and diffuse cSAH. The angiography showed vasoconstriction of the right anterior cerebral artery and stenosis of both middle cerebral arteries. Nimodipine treatment was initiated and vasoconstriction completely regressed on day 16 after the first headache. Conclusion. Our case shows a severe reversible cerebral vasoconstriction syndrome where both haemorrhagic and ischemic complications were present at the same time. The history we reported shows that reversible cerebral vasoconstriction syndrome is still underrecognized, in particular in general emergency departments.

  5. [A clinical study of single subcortical cerebral infarction of middle cerebral artery territory].

    Science.gov (United States)

    Yang, L; Yu, L; Qin, W; Zhang, X Y; Li, Y; Xu, J H; Hu, X Z; Yuan, J L; Gu, H; Hu, W L

    2016-10-01

    Objective: To explore the clinical characteristics of single subcortical cerebral infarction of middle cerebral artery (MCA) territory and the possible pathogenesis. Methods: A total of 344 cases diagnosed as single subcortical cerebral infarction of MCA territory were enrolled in the study and divided into the parent artery disease (PAD) group and the non-PAD group according to whether the MCA stenosis was presented or not. A total of 312 cases diagnosed as single subcortical cerebral infarction of MCA territory were divided into the BAD group and the SVD group according to the relationship between the lesion sites and MCA. Differences in the clinical and imaging feature were compared between different groups. Results: A total of 32 patients were in the PAD group. Compared with the non-PAD group, patients in the PAD group were found with higher prevalence of asymptomatic cerebral arterial atherosclerosis [93.8%(30/32) vs 57.1%(178/312), P territory has different etiology and pathogenesis. Evidence of systemic atherosclerosis should be carefully searched in patients with branch atheromatous disease.

  6. Locations of cerebral infarctions in tuberculous meningitis

    Energy Technology Data Exchange (ETDEWEB)

    Hsieh, F.Y.; Chia, L.G. (Section of Neurology, Taichung Veterans General Hospital (Taiwan)); Shen, W.C. (Section of Neuroradiology, Taichung Veterans General Hospital (Taiwan))

    1992-06-01

    The locations of cerebral infarctions were studied in 14 patients with tuberculous meningitis (TBM) and 173 patients with noninflammatory ischemic stroke (IS). In patients with TBM, 75% of infarctions occurred in the 'TB zone' supplied by medial striate and thalamoperforating arteries; only 11% occurred in the 'IS zone' supplied by lateral striate, anterior choroidal and thalamogeniculate arteries. In patients with IS, 29% of infarctions occurred in the IS zone, 29% in the subcortical white matter, and 24% in (or involving) the cerebral cortex. Only 11% occurred in the TB zone. Bilaterally symmetrical infarctions of the TB zone were common with TBM (71%) but rare with IS (5%). (orig.).

  7. Epidemiology of cerebral palsy in Southern Denmark

    DEFF Research Database (Denmark)

    Frøslev-Friis, Christina; Dunkhase-Heinl, Ulrike; Andersen, Johnny Dohn Holmgren

    2015-01-01

    INTRODUCTION: The aim of this study was to describe the prevalence, subtypes, severity and neuroimaging findings of cerebral palsy (CP) in a cohort of children born in Southern Denmark. Risk factors were analysed and aetiology considered. METHODS: A population-based cohort study covering 17...... prevention of CP is possible if the numbers of preterm births and multiple pregnancies can be reduced. FUNDING: The Danish Cerebral Palsy Follow-up Programme is supported by the foundation "Ludvig og Sara Elsass Fond". TRIAL REGISTRATION: 2008-58-0034.......,580 live births from 2003 to 2008. RESULTS: The study included 43 children diagnosed with CP. The overall prevalence of CP was 2.4 per 1,000 live births (95% confidence interval (CI): 1.8-3.2). The gestational age (GA)-specific prevalence ranged from 63.5 per 1,000 live births for GA

  8. Computed tomography in spastic cerebral palsy

    Energy Technology Data Exchange (ETDEWEB)

    Pedersen, H.; Taudorf, K.; Melchior, J.C.

    1982-09-01

    Eighty-three children with spastic cerebral palsy (CP) were examined with cranial CT. In 56 cases the CT findings were abnormal. The most frequent abnormality was atrophy, present in 44 patients. The frequency of pathologic CT increased with severity of the CP. Patients with CP of postnatal aetiology more often had abnormal CT than patients with other known causes. Pathologic CT findings were seen more often in patients with seizures than in patients without. Infarctions and hemiatrophy were much more frequent in patients with hemiplegia than in patients with other types of spastic CP. A special kind of central atrophy, called isolated atrophy around the cella media, is described. This condition was seen in 20% of cases, most often in hemi- and paraplegic patients. Early infarctions in the border areas between the vascular territories of the internal carotid and the posterior cerebral artery may be the reason for this kind of atrophy.

  9. Natural history of cerebral cavernous malformations.

    Science.gov (United States)

    Ene, Chibawanye; Kaul, Anand; Kim, Louis

    2017-01-01

    Cerebral cavernous malformations (CCM) are vascular abnormalities of the central nervous system with an incidence of 0.4-0.5% and an annual rate of hemorrhage ranging from 0.7% to 1%. Most lesions are located in the cerebral hemisphere but some occur in deeper locations such as the basal ganglia and pons. The most common symptoms during presentation are headache, seizures, and focal neurologic deficits. Surgery remains the most effective treatment modality for symptomatic CCM, while the management of incidental CCM remains controversial. Factors associated with increased risk of hemorrhage include being female and less than 40 years old. This finding, however, is not consistent in all natural history studies evaluated. During follow-up, the most important and consistent risk factor for rebleed was a prior hemorrhage. Here, we provide an indepth but concise review of the literature regarding the natural history of CCMs. © 2017 Elsevier B.V. All rights reserved.

  10. Intraoperative cerebral blood flow imaging of rodents

    Science.gov (United States)

    Li, Hangdao; Li, Yao; Yuan, Lu; Wu, Caihong; Lu, Hongyang; Tong, Shanbao

    2014-09-01

    Intraoperative monitoring of cerebral blood flow (CBF) is of interest to neuroscience researchers, which offers the assessment of hemodynamic responses throughout the process of neurosurgery and provides an early biomarker for surgical guidance. However, intraoperative CBF imaging has been challenging due to animal's motion and position change during the surgery. In this paper, we presented a design of an operation bench integrated with laser speckle contrast imager which enables monitoring of the CBF intraoperatively. With a specially designed stereotaxic frame and imager, we were able to monitor the CBF changes in both hemispheres during the rodent surgery. The rotatable design of the operation plate and implementation of online image registration allow the technician to move the animal without disturbing the CBF imaging during surgery. The performance of the system was tested by middle cerebral artery occlusion model of rats.

  11. The Child with Cerebral Palsy and Anaesthesia

    Directory of Open Access Journals (Sweden)

    A Rudra

    2008-01-01

    Full Text Available Cerebral palsy (CP is the result of an injury to the developing brain during the antenatal, perinatal or postnatal period. Clinical manifestation relate to the areas affected. Patients with CP often present for elective surgical proce-dures to correct various deformities. Anaesthetic concerns of anaesthesia are intraoperative hypothermia , and slow emergence. Suxamethonium does not cause hyperkalaemia in these patients, and a rapid sequence induction may be indicated. Temperature should be monitored and an effort made to keep the patient warm. Cerebral abnormalities may lead to slow awakening; the patient should remain intubated until fully awake and airway reflexes have returned. Pulmonary infection can complicate the postoperative course. Postoperative pain management and the prevention of muscle spasms are important and drugs as baclofen and botulinum toxin are discussed. Epidural analgesia is particu-larly valuable when major orthopaedic procedures are performed.

  12. Botulinum toxin in children with cerebral palsy.

    Science.gov (United States)

    Singhi, Pratibha; Ray, Munni

    2004-12-01

    Botulinum toxin is a neurotoxin that blocks the synaptic release of acetylcholine from cholinergic nerve terminals mainly at the neuromuscular junction, resulting in irreversible loss of motor end plates. It is being widely tried as a targeted antispasticity treatment in children with cerebral palsy. A number of studies have shown that it reduces spasticity and increases the range of motion and is particularly useful in cases with dynamic contractures. However improvement in function has not been convincingly demonstrated. It is an expensive mode of therapy and the injections need to be repeated after 3-6 months. Whereas Botulinum toxin can be a valuable adjunct in select cases, it should not be projected as a panacea for children with spastic cerebral palsy.

  13. The Age of Human Cerebral Cortex Neurons

    Energy Technology Data Exchange (ETDEWEB)

    Bhardwaj, R D; Curtis, M A; Spalding, K L; Buchholz, B A; Fink, D; Bjork-Eriksson, T; Nordborg, C; Gage, F H; Druid, H; Eriksson, P S; Frisen, J

    2006-04-06

    The traditional static view of the adult mammalian brain has been challenged by the realization of continuous generation of neurons from stem cells. Based mainly on studies in experimental animals, adult neurogenesis may contribute to recovery after brain insults and decreased neurogenesis has been implicated in the pathogenesis of neurological and psychiatric diseases in man. The extent of neurogenesis in the adult human brain has, however, been difficult to establish. We have taken advantage of the integration of {sup 14}C, generated by nuclear bomb tests during the Cold War, in DNA to establish the age of neurons in the major areas of the human cerebral cortex. Together with the analysis of the cortex from patients who received BrdU, which integrates in the DNA of dividing cells, our results demonstrate that whereas non-neuronal cells turn over, neurons in the human cerebral cortex are not generated postnatally at detectable levels, but are as old as the individual.

  14. Cerebral blood flow in normal pressure hydrocephalus

    Energy Technology Data Exchange (ETDEWEB)

    Mamo, H.L.; Meric, P.C.; Ponsin, J.C.; Rey, A.C.; Luft, A.G.; Seylaz, J.A.

    1987-11-01

    A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase in CBF in patients with NPH, which was confirmed by the favorable outcome of 88% of patients shunted. The majority of patients with senile and presenile dementia showed a decrease or no change in CBF after CSF removal. It is suggested that although changes in CBF and clinical symptoms of NPH may have the same cause, i.e., changes in the cerebral intraparenchymal pressure, there is no simple direct relation between these two events. The mechanism underlying the loss of autoregulation observed in NPH is also discussed.

  15. Cerebral blood flow and metabolism during sleep

    DEFF Research Database (Denmark)

    Madsen, Peter Lund; Vorstrup, S

    1991-01-01

    A review of the current literature regarding sleep-induced changes in cerebral blood flow (CBF) and cerebral metabolic rate (CMR) is presented. Early investigations have led to the notion that dreamless sleep was characterized by global values of CBF and CMR practically at the level of wakefulness......, while rapid eye movement (REM) sleep (dream sleep) was a state characterized by a dramatically increased level of CBF and possibly also of CMR. However, recent investigations firmly contradict this notion. Investigations on CBF and CMR performed during non-REM sleep, taking the effect of different...... levels of sleep into consideration, show that light sleep (stage II) is characterized by global levels of CBF and CMR only slightly reduced by 3-10% below the level associated with wakefulness, whereas CBF and CMR during deep sleep (stage III-IV) is dramatically reduced by 25-44%. Furthermore, recent...

  16. Evaluation of cerebral dyschromatopsia using color afterimage.

    Science.gov (United States)

    Koyama, Shinichi; Kezuka, Machiko; Hibino, Haruo; Tomimitsu, Hiroyuki; Kawamura, Mitsuru

    2006-02-06

    Cerebral dyschromatopsia is traditionally evaluated by color discrimination tests such as the Farnsworth-Maunsell 100 Hue Test. These tests are also used to evaluate color-perception deficits caused by eye disease, and they do not tell us whether color perception is impaired in the eye or in the brain. Here, we used color afterimage to isolate color-perception deficits in the brain from those in the eyes, in a patient with cerebral dyschromatopsia. The results showed that the patient perceived color afterimage of yellow and blue with abnormal duration and chromaticity. On the other hand, the patient performed normally on the Farnsworth-Maunsell 100 Hue Test. We conclude that the color afterimage test would be useful to evaluate color perception in the brain.

  17. Neural perspectives of cerebral correlates of giftedness.

    Science.gov (United States)

    Chen, A C; Buckley, K C

    1988-07-01

    Giftedness is defined as some special endowment or propensity for creativity, skill, and eminent achievement, found in relatively few individuals among the population. A high order of mental power (IQ), creativity, and motivation (task commitment) appear to be the most universally recognized attributes of the gifted. This report summarizes current knowledge of the cerebral correlates of intelligence and creativity, including physiological measures of EEG, cortical power spectrum, brain evoked potentials, and positron emission tomography. Controversy, debates, contentions, formal hypotheses, and research issues are considered. We are especially interested in the formulation of the deterministic function of EEG-brain dynamics. A CHAOS modeling on hierarchy of cognitive organization and cerebral processing in the gifted is suggested.

  18. Cerebral palsy characterization by estimating ocular motion

    Science.gov (United States)

    González, Jully; Atehortúa, Angélica; Moncayo, Ricardo; Romero, Eduardo

    2017-11-01

    Cerebral palsy (CP) is a large group of motion and posture disorders caused during the fetal or infant brain development. Sensorial impairment is commonly found in children with CP, i.e., between 40-75 percent presents some form of vision problems or disabilities. An automatic characterization of the cerebral palsy is herein presented by estimating the ocular motion during a gaze pursuing task. Specifically, After automatically detecting the eye location, an optical flow algorithm tracks the eye motion following a pre-established visual assignment. Subsequently, the optical flow trajectories are characterized in the velocity-acceleration phase plane. Differences are quantified in a small set of patients between four to ten years.

  19. Cerebral hypoxia and ischemia in preterm infants

    Directory of Open Access Journals (Sweden)

    Alberto Ravarino

    2014-06-01

    Full Text Available Premature birth is a major public health issue internationally affecting 13 million babies worldwide. Hypoxia and ischemia is probably the commonest type of acquired brain damage in preterm infants. The clinical manifestations of hypoxic-ischemic injury in survivors of premature birth include a spectrum of cerebral palsy and intellectual disabilities. Until recently, the extensive brain abnormalities in preterm neonates appeared to be related mostly to destructive processes that lead to substantial deletion of neurons, axons, and glia from necrotic lesions in the developing brain. Advances in neonatal care coincide with a growing body of evidence that the preterm gray and white matter frequently sustain less severe insults, where tissue destruction is the minor component. Periventricular leukomalacia (PVL is the major form of white matter injury and consists classically of focal necrotic lesions, with subsequent cyst formation, and a less severe but more diffuse injury to cerebral white mater, with prominent astrogliosis and microgliosis but without overt necrosis. With PVL a concomitant injury occurs to subplate neurons, located in the subcortical white matter. Severe hypoxic-ischemic insults that trigger significant white matter necrosis are accompanied by neuronal degeneration in cerebral gray and white matter. This review aims to illustrate signs of cerebral embryology of the second half of fetal life and correlate hypoxic-ischemic brain injury in the premature infant. This should help us better understand the symptoms early and late and facilitate new therapeutic strategies. Proceedings of the International Course on Perinatal Pathology (part of the 10th International Workshop on Neonatology · October 22nd-25th, 2014 · Cagliari (Italy · October 25th, 2014 · The role of the clinical pathological dialogue in problem solving Guest Editors: Gavino Faa, Vassilios Fanos, Peter Van Eyken

  20. Lower urinary tract dysfunction in cerebral palsy.

    OpenAIRE

    Reid, C. J.; Borzyskowski, M

    1993-01-01

    The clinical features and management of 27 children with cerebral palsy referred with symptoms of lower urinary tract dysfunction were reviewed. The mean age at referral was 9.9 years. Daytime urinary incontinence was the commonest presenting symptom. Videourodynamic studies were abnormal in 23 patients (85%). Only two children had evidence of upper renal tract damage. Treatment was determined by urodynamic findings, and led to improvement in symptoms in all patients for whom there was follow...

  1. Rhino Cerebral Mucormycosis - A Case Report

    Directory of Open Access Journals (Sweden)

    N Eswar

    2006-01-01

    Full Text Available Rhino cerebral Mucormycosis is an opportunistic infection caused by a saprophytic fungus which is found in soil, decaying fruits and vegetables. Usually predisposing factors for this infection are poorly controlled diabetes, ketoacidosis, leukemia, immunodeficiency states, prolonged steroid therapy etc. The fungus once entering the susceptible host do cause highly invasive and fulminant infection usually with fatal outcome. Early recognition of this condition is highly essential to initiate immediate life saving measures.

  2. Cerebral sex dimorphism and sexual orientation.

    Science.gov (United States)

    Manzouri, Amirhossein; Savic, Ivanka

    2018-03-01

    The neurobiology of sexual orientation is frequently discussed in terms of cerebral sex dimorphism (defining both functional and structural sex differences). Yet, the information about possible cerebral differences between sex-matched homo and heterosexual persons is limited, particularly among women. In this multimodal MRI study, we addressed these issues by investigating possible cerebral differences between homo and heterosexual persons, and by asking whether there is any sex difference in this aspect. Measurements of cortical thickness (Cth), subcortical volumes, and functional and structural resting-state connections among 40 heterosexual males (HeM) and 40 heterosexual females (HeF) were compared with those of 30 homosexual males (HoM) and 30 homosexual females (HoF). Congruent with previous reports, sex differences were detected in heterosexual controls with regard to fractional anisotropy (FA), Cth, and several subcortical volumes. Homosexual groups did not display any sex differences in FA values. Furthermore, their functional connectivity was significantly less pronounced in the mesial prefrontal and precuneus regions. In these two particular regions, HoM also displayed thicker cerebral cortex than other groups, whereas HoF did not differ from HeF. In addition, in HoM the parietal Cth showed "sex-reversed" values, not observed in HoF. Homosexual orientation seems associated with a less pronounced sexual differentiation of white matter tracts and a less pronounced functional connectivity of the self-referential networks compared to heterosexual orientation. Analyses of Cth suggest that male and female homosexuality are not simple analogues of each other and that differences from heterosexual controls are more pronounced in HoM. © 2017 Wiley Periodicals, Inc.

  3. Cerebral paragonimiasis that manifested as intracranial hemorrhage.

    Science.gov (United States)

    Chen, Jingyu; Chen, Zhi; Li, Fei; Lin, Jiangkai; Meng, Hui; Feng, Hua

    2010-12-01

    The purpose of this study was to review 14 rare cases of cerebral paragonimiasis that first manifested as intracranial hemorrhage (ICH), and to investigate the characteristics of clinical manifestation, diagnosis, and treatment of the disease. The authors have encountered 14 cases of cerebral paragonimiasis in patients between the ages of 6 and 16 years (mean age 11.5 years) who presented with sudden headache, nausea, and vomiting. Three of them were affected with varying degrees of limb hemiplegia, and in 1 this was combined with high fever; the blood eosinophil count and enzyme-linked immunosorbent assay showed positive results too. The ICHs were observed with cranial CT and MR imaging, and lung lesions were also detected in 5 cases on chest CT scans. Ten of the diagnosed cases were treated with oral praziquantel. Three of these patients were given carbamazepine from the beginning of parasiticidal treatment to prevent seizures; 4 of the remaining 7 patients experienced epileptic seizures during the treatment process. Four patients needed surgery to remove the lesions, and these individuals received praziquantel treatment right after the surgery. Pathological examinations demonstrated eosinophilic granuloma in these patients. There was no disease recurrence or epilepsy in 11-40 months of follow-up; however, mild hemiplegia could still be observed in 2 cases after 12 months and 17 months of follow-up. The possibility of cerebral paragonimiasis should be considered when ICH is detected in young patients who are either from an endemic area or have recently visited such an area; the relatively small amount of hemorrhage in cerebral paragonimiasis is often represented as small lesions surrounded by disproportionately larger edema on the imaging study. Preventive antiepileptic drugs should be used along with the administration of parasiticide.

  4. CT scan findings in cerebral paragonimiasis

    Energy Technology Data Exchange (ETDEWEB)

    Udaka, Fukashi; Okuda, Bungo; Okada, Masako; Okae, Shunji; Kameyama, Masakuni (Chikamori Hospital, Kochi (Japan))

    1982-12-01

    Computed tomography was performed on 5 patients with chronic cerebral paragonimiasis. CT showed solitary or multiple, amorphous, round, or oval calcifications, and ventricular enlargement in all 5 cases. A large low-density area is also found in 4 of the 5 cases. These CT findings are compatible with previously reported findings of simple X-ray films of the skull, pneumoencephalography, and pathological studies.

  5. [Cerebral infarctions in vertebrobasilar artery atherosclerosis].

    Science.gov (United States)

    Anufriev, P L; Evdokimenko, A N; Gulevskaya, T S

    2018-01-01

    to obtain more specific information on the morphology and pathogenesis of cerebral infarctions occurring in vertebrobasilar artery (VBA) atherosclerosis. Macro- and microscopic investigations of the brain, its arterial system, and heart were conducted in 69 autopsy cases with infarctions located in the vertebrobasilar system (VBS) in atherosclerosis. 69 cases were found to have 206 VBA infarctions of various extent and locations. The detected infarctions were single and multiple in 27 and 42 cases, respectively. The detected infarctions included extensive (n=7), large (n=9), medium (n=63), small deep (lacunar) (n=97), and small superficial (n=30). The brain stem showed lacunar infarctions most frequently (76% of the infarctions at this site). Medium and small infarctions were identified at the same frequency in the cerebral hemispheres and cerebellum. The occurrence of 94% of the extensive and large infarctions was ascertained to be pathogenetically associated with atherothrombotic occlusion of the intracranial arteries in the VBS. 76% of the small infarctions occurred through the mechanism of cerebral vascular insufficiency in tandem atherostenosis of VBAs in conjunction with an additional decrease in cerebral blood flow under the influence of an extracerebral factor (coronary heart disease). Medium infarctions were approximately equifrequently due to the two aforementioned causes and, in some cases, to cardiogenic thromboembolism of VBAs. Infarctions were multiple in most cases; while recent large atherothrombotic infarctions were frequently concurrent with small organized infarctions resulting from tandem atherostenosis of VBAs. This investigation could establish the relationship between the site, extent, and pathogenetic factors of infarctions in the VBA bed in atherosclerosis, as well as the prognostic value of small infarctions as predictors for severe ischemic stroke.

  6. Regional cerebral blood flow in Angelman syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Guecueyener, K. (Dept. of Pediatric Neurology, Faculty of Medicine, Gazi Univ., Ankara (Turkey)); Goekcora, N. (Dept. of Nuclear Medicine, Faculty of Medicine, Gazi Univ., Ankara (Turkey)); Ilgin, N. (Dept. of Nuclear Medicine, Faculty of Medicine, Gazi Univ., Ankara (Turkey)); Buyan, N. (Dept. of Pediatric Neurology, Faculty of Medicine, Gazi Univ., Ankara (Turkey)); Sayli, A. (Dept. of Molecular Biology and Genetics, Faculty of Medicine, Gazi Univ., Ankara (Turkey))

    1993-07-01

    A patient with typical features of Angelman syndrome - a genetically inherited disorder involving developmental delay, ataxia, episodes of paroxysmal laughter and brachiocephaly - was studied with single-photon emission tomography. Hyperfusion found in the left frontal and left temporoparietal regions can provide insights into the functional cerebral pathology, which may be due to a disturbance of the developmental process related to a chromosomal abnormality. (orig.)

  7. Hemorragia cerebral secundaria a trombocitopenia por varicela

    Directory of Open Access Journals (Sweden)

    Jairo Lizarazo

    2016-08-01

    Full Text Available Se presenta el caso de un hombre de 44 años, previamente sano, con varicela, trombocitopenia grave, manifestaciones hemorrágicas en mucosas y una extensa hemorragia cerebral en el hemisferio derecho. Su tratamiento incluyó la transfusión de plaquetas y altas dosis de esteroides. El paciente mejoró, aunque persistieron la hemianopsia homónima izquierda y la epilepsia, tratada con medicación.

  8. Cerebral palsy dysphagia: a systematic review

    OpenAIRE

    Menezes, Edênia da Cunha; Santos, Flávia Aparecida Hora; Alves, Flávia Lôbo

    2017-01-01

    ABSTRACT Cerebral palsy (CP) encompasses a group of definitive and non-progressive conditions, with a non-progressive character and its installation in neonatal period. Motor disorders caused by CP may lead to changes in swallowing, resulting in limitations in the activities that are attributed to non-progressive disorders that do not reach the developing child's brain. This article reviews the clinical aspects of dysphagia in CP and the treatments in the area. Only papers published in the pe...

  9. Hypocapnia and cerebral hypoperfusion in orthostatic intolerance

    Science.gov (United States)

    Novak, V.; Spies, J. M.; Novak, P.; McPhee, B. R.; Rummans, T. A.; Low, P. A.

    1998-01-01

    BACKGROUND AND PURPOSE: Orthostatic and other stresses trigger tachycardia associated with symptoms of tremulousness, shortness of breath, dizziness, blurred vision, and, often, syncope. It has been suggested that paradoxical cerebral vasoconstriction during head-up tilt might be present in patients with orthostatic intolerance. We chose to study middle cerebral artery (MCA) blood flow velocity (BFV) and cerebral vasoregulation during tilt in patients with orthostatic intolerance (OI). METHODS: Beat-to-beat BFV from the MCA, heart rate, CO2, blood pressure (BP), and respiration were measured in 30 patients with OI (25 women and 5 men; age range, 21 to 44 years; mean age, 31.3+/-1.2 years) and 17 control subjects (13 women and 4 men; age range, 20 to 41 years; mean age, 30+/-1.6 years); ages were not statistically different. These indices were monitored during supine rest and head-up tilt (HUT). We compared spontaneous breathing and hyperventilation and evaluated the effect of CO2 rebreathing in these 2 positions. RESULTS: The OI group had higher supine heart rates (Ppulse pressure (Ptachycardia (Ptachycardia and worsened symptoms of OI; these symptoms and indices were improved within 2 minutes of CO2 rebreathing. The relationships between CO2 and BFV and heart rate were well described by linear regressions, and the slope was not different between control subjects and patients with OI. CONCLUSIONS: Cerebral vasoconstriction occurs in OI during orthostasis, which is primarily due to hyperventilation, causing significant hypocapnia. Hypocapnia and symptoms of orthostatic hypertension are reversible by CO2 rebreathing.

  10. Cerebral oximetry during ventricular and supraventricular tachycardia

    OpenAIRE

    Gräser, Saskia

    2017-01-01

    Background: Ventricular tachycardia (VT) and supraventricular tachycardia (SVT) affect the hemodynamic status of the patient. Standard monitoring in clinical practice includes measurement of peripheral arterial saturation (SaO2) and mean arterial pressure (MAP). However, these parameters only partly reflect the perfusion in different microvascular beds. Therefore, evaluation of microcirculation in end organs may be of clinical value, to prevent end organ damage during VT and SVT. Cerebral...

  11. Literacy development in children with cerebral palsy

    OpenAIRE

    Critten, Valerie

    2013-01-01

    This thesis concerns the literacy difficulties of fifteen children with cerebral palsy (CP). The children were an opportunistic sample from two schools, and were initially selected on the basis that they had typical abilities in other school subjects. A review of the literature pertaining to the development of literacy and related aspects of cognitive development in typically-developing children and children with CP informed the development of the research strategy. The children's literacy, t...

  12. Molecular basis of human cerebral malaria development

    OpenAIRE

    Wah, Saw Thu; Hananantachai, Hathairad; Kerdpin, Usanee; Plabplueng, Chotiros; Prachayasittikul, Virapong; Nuchnoi, Pornlada

    2016-01-01

    Cerebral malaria is still a deleterious health problem in tropical countries. The wide spread of malarial drug resistance and the lack of an effective vaccine are obstacles for disease management and prevention. Parasite and human genetic factors play important roles in malaria susceptibility and disease severity. The malaria parasite exerted a potent selective signature on the human genome, which is apparent in the genetic polymorphism landscape of genes related to pathogenesis. Currently, m...

  13. Uncommon Etiology for Seizure: Cerebral Hyperperfusion Syndrome

    OpenAIRE

    Mohankumar Kurukumbi; Ahn Truong; Naghemeh Pirsaharkhiz

    2017-01-01

    Cerebral hyperperfusion syndrome (CHS) is a rare life-threatening complication of carotid endarterectomy (CEA) and carotid artery stenting (CAS) for carotid artery stenosis. The incidence varies between 0 and 3%, depending on the severity of the stenosis, perioperative hypertension, and contralateral carotid stenosis. This case report reports a 53-year-old female patient presenting with decreased alertness and multiple tonic-clonic seizures, in the background of bilateral CEA. She was found t...

  14. Cerebral activation pattern in primary writing tremor

    OpenAIRE

    Berg, D; Preibisch, C; Hofmann, E; Naumann, M

    2000-01-01

    OBJECTIVE—To compare the cerebral activation pattern during writing of patients with writing tremor with healthy controls using functional MRI
METHODS—Three patients with writing tremor and 10 healthy controls were examined using a 1.5 Tesla scanner. All subjects performed a paradigm of alternating 30 second periods of rest or writing. For functional imaging 60 EPI multislice data sets were acquired. All images were analyzed using SPM96 software. Data were analyzed for the grou...

  15. Subcortical cerebral infarctions in sickle cell trait.

    OpenAIRE

    Reyes, M G

    1989-01-01

    At necropsy, two patients with sickle cell trait and progressive motor and visual deficits, lethargy and coma showed infarctions of the deep cerebral white matter and brain stem. The findings in these patients and another reported in the literature suggest that subcortical infarctions may be more common in sickle cell trait than has been recognised and should be suspected in any patient with sickle cell trait who presents with an unusual neurological illness.

  16. Odontopediatrics integral treatment in cerebral paralysis.

    OpenAIRE

    Nima Bermejo, Gabriel; Bachiller en Odontología. Facultad de Odontología, Universidad Nacional Mayor de San Marcos, Lima, Perú.; Romero Velarde, Mariela Ruthsana; Departamento Académico de Estomatología Pediátrica. Facultad de Odontología, Universidad Nacional Mayor de San Marcos, Lima, Perú.

    2014-01-01

    Report a case of girl of 4 years 3 months with congenital cerebral palsy distonic caused by citomegalovirus infectión with convulsive sindrome. The patient was referred to the pediatric dentistry departament at the dental school of the Universidad Nacional Mayor de San Marcos (UNMSM) for her odontopediatric treatment. The patient had an integral evaluation and treatment with no conventional dental procedures, without consciencious sedation. Having in consideration her age and cooperation leve...

  17. Growth hormone deficiency and cerebral palsy

    Directory of Open Access Journals (Sweden)

    Jesús Devesa

    2010-09-01

    Full Text Available Jesús Devesa1,2, Nerea Casteleiro2, Cristina Rodicio2, Natalia López2, Pedro Reimunde1,21Department of Physiology, School of Medicine of Santiago de Compostela, Spain; 2Medical Center Proyecto Foltra, 15886 Teo, SpainAbstract: Cerebral palsy (CP is a catastrophic acquired disease, occurring during development of the fetal or infant brain. It mainly affects the motor control centres of the developing brain, but can also affect cognitive functions, and is usually accompanied by a cohort of symptoms including lack of communication, epilepsy, and alterations in behavior. Most children with cerebral palsy exhibit a short stature, progressively declining from birth to puberty. We tested here whether this lack of normal growth might be due to an impaired or deficient growth hormone (GH secretion. Our study sample comprised 46 CP children, of which 28 were male and 18 were female, aged between 3 and 11. Data obtained show that 70% of these children lack normal GH secretion. We conclude that GH replacement therapy should be implemented early for CP children, not only to allow them to achieve a normal height, but also because of the known neurotrophic effects of the hormone, perhaps allowing for the correction of some of the common disabilities experienced by CP children.Keywords: growth hormone, IGF-I, cerebral palsy, short stature

  18. [New developments in spastic unilateral cerebral palsy].

    Science.gov (United States)

    Chabrier, S; Roubertie, A; Allard, D; Bonhomme, C; Gautheron, V

    2010-01-01

    Hemiplegic (or spastic unilateral) cerebral palsy accounts for about 30% of all cases of cerebral palsy. With a population prevalence of 0.6 per 1000 live births, it is the most common type of cerebral palsy among term-born children and the second most common type after diplegia among preterm infants. Many types of prenatal and perinatal brain injury can lead to congenital hemiplegia and brain MRI is the most useful tool to classify them with accuracy and to provide early prognostic information. Perinatal arterial ischemic stroke thus appears as the leading cause in term infants, whereas encephalopathy of prematurity is the most common cause in premature babies. Other causes include brain malformations, neonatal sinovenous thrombosis, parenchymal hemorrhage (for example due to coagulopathy or alloimmune thrombocytopenia) and the more recently described familial forms of porencephaly associated with mutations in the COL4A1 gene. In adjunction with pharmacologic treatment (botulinium neurotoxin injection), new evidence-based rehabilitational interventions, such as constraint-induced movement therapy and mirror therapy, are increasingly being used.

  19. Normobaric oxygen for cerebral ischemic injury

    Science.gov (United States)

    Chen, Chunhua; Cui, Haimeng; Li, Zihe; Wang, Ruifeng; Zhou, Changman

    2013-01-01

    Oxygen inhalation has been shown to increase oxygen supply to tissues after cerebral ischemia/ reperfusion injury, protecting injured neural cells. However, hyperbaric oxygen may aggravate oxidative stress. By contrast, normobaric oxygen has the rapid and non-invasive characteristics and may have therapeutic effects on ischemic/hypoxic disease. Rats inhaled normobaric oxygen (95% O2) for 6 consecutive days, and then a rat model of focal cerebral ischemia was established. Nissl and 2,3,5-triphenyltetrazolium chloride (TTC) staining revealed that normobaric oxygen pretreatment improved neurological deficits and reduced infarct volume. Immunohistochemical staining and western blot assay revealed that the expression of hypoxia-inducible factor-1α, Notch-1, vascular endothelial growth factor and erythropoietin were increased. Behavioral studies also verified that neurological deficit scores increased. The hypoxia-inducible factor inhibitor 2-methoxyestradiol treatment at 1 hour before administration of normobaric oxygen could suppress the protective effect of normobaric oxygen. Given these observations, normobaric oxygen pretreatment may alleviate cerebral ischemic injury via the hypoxia-inducible factor signal pathway. PMID:25206609

  20. Computed tomographic findings of cerebral paragonimiasis

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Nak Kwan; Nam, Kyung Jin; Park, Churl Min; Eun, Chung Kie; Lee, Sun Wha [Kyung Hee Unversity Hospital, Seoul (Korea, Republic of)

    1983-03-15

    Paragonimiasis is widely distributed in Far East and Southeast Asia, particularly in Korea. The central nervous system is the most frequent location for paragonimiasis outside the lungs. We analyzed the computed tomographic findings of 17 cases which were diagnosed pathologically and clinically as cerebral paragonimiasis. The results were as follows: 1. The ratio of male to female was 10 : 7 and about 88% of cases were under the age of 40 years. 2. The common locations of cerebral paragonimiasis were the occipital (12 cases) and temporal (11 cases) lobes. 3. Precontrast CT findings of cerebral paragonimiasis were low density with calcifications in 6 cases, low and isodensities in 4 cases, mixed densities in 3 cases, only low density in 2 cases and only calcification in 2 cases. Hydrocephalus (7 cases), mass effect (6 cases), atrophic change (6 cases) and cyst formation (3 cases) were associated. 4. The shape of calcifications in CT scan were soap-bubble or ring in 6 cases, nodular or oval in 6 cases, stipple in 4 cases and amorphous conglomerated in 2 cases. 5. The contrast -enhanced 8 cases were 5 ring or rim like, 2 nodular and 1 irregular enhancements, while 9 cases were not enhanced.

  1. Epilepsy in children with cerebral palsy.

    Science.gov (United States)

    Aneja, S; Ahuja, B; Taluja, V; Bhatia, V K

    2001-02-01

    This article deals with the clinical profile of children with cerebral palsy and epilepsy, and to study the clinical predictors of response to anti-epileptic drugs. It is a prospective hospital based follow-up study. All the children who presented with cerebral palsy and history of seizure (other than neonatal seizures) over a period of one year were included. Seizures were classified according to ILAE classification. An EEG was obtained in all cases. Neuroimaging was done in all patients. Eighty-five patients were studied and followed for minimum of 12 months. Perinatal factors accounted for 62 (72.3%) cases. The motor deficits seen were quadriparesis (n = 64), hemiplegia (n = 12) and diplegia (n = 9). Associated mental retardation was seen in 80.9% patients with quadriparesis. A predominance of generalised epilepsy was seen with generalised tonic clonic seizures (32.9%) followed by mycolonic seizures (30.6%) and localisation related epilepsy (24.7%). The patients with quadriparesis were more likely to have generalised epilepsy and 52.4% of them required two or more anti-epileptic drugs for control of seizures. Patients with hemiplegia had localisation related epilepsy in 83.3% of cases. On multivariate analysis presence of quadriparesis, microcephaly, mental retardation and myoclonic epilepsy were found to predict the poor response to AED. Epilepsy in patients with cerebral palsy is of severe nature and difficult to control. Presence of quadriparesis, mental retardation and myoclonic seizures was predictive of poor response to anti- epileptic drugs.

  2. Hemicorea asociada a toxoplasmosis cerebral y SIDA

    Directory of Open Access Journals (Sweden)

    N.S. garretto

    1995-03-01

    Full Text Available Se observan complicaciones neurológicas en 40% de enfermos con SIDA. De estos, en 10% puede ser la manifestation inicial de la enfermedad. En otro 11% pueden aparecer trastornos del movimiento. Comunicamos el primer caso de hemicorea asociada a toxoplasmosis cerebral y SIDA en nuestro pais. Hombre de 26 anos, con diagnostico de SIDA y toxoplasmosis cerebral. Habia comenzado con crisis motoras simples de hemicuerpo izquierdo, con generalization secundaria y luego perdida de fuerza progresiva en dicho hemicuerpo. La RMN de cérebro mostro una lesion frontal derecha y otra temporo-occipital izquierda, con gran edema perilesional y efecto de masa. Las serologias para HIV y toxoplasmosis fueron positivas. Comenzo tratamiento con sulfadiazina y pirimetamina. Al duodecimo dia aparecieron movimientos involuntários dei pie izquierdo, coreicos, que se extendieron mas tarde a todo ese miembro inferior y luego al hemicuerpo. Nueva RMN de cérebro mostro disminucion dei edema y efecto de masa de las lesiones. Sin embargo, se observo una nueva lesion a nivel peduncular derecho. Movimientos involuntarios en pacientes con toxoplasmosis cerebral comenzaron a describirse recientemente solo en pacientes con SIDA. El presente seria el decimotercer caso de la literatura mundial y el primero en nuestro pais de hemicorea asociada a toxoplasmosis y SIDA.

  3. Aphasia following anterior cerebral artery occlusion

    Energy Technology Data Exchange (ETDEWEB)

    Shimosaka, Shinichi; Waga, Shiro; Kojima, Tadashi; Shimizu, Takeo; Morikawa, Atsunori (Mie Univ., Tsu (Japan). School of Medicine)

    1982-10-01

    We have report two cases of aphasia that had infarcts in the distribution of the left or right anterior cerebral artery, as confirmed by computed tomography. Case 1 is a right-handed, 65-year-old man in whom computerized tomographic scanning revealed an infarction of the territory of the left anterior cerebral artery after the clipping of the anterior communicating artery aneurysm. The standard language test of aphasia (SLTA) revealed non-fluent aphasia with dysarthria, good comprehension, almost normal repetition with good articulation, and a defectiveness in writing. This syndrome was considered an instance of transcortical motor aphasia. Although three years had passed from the onset, his aphasia did not show any improvement. Case 2 is a 37-year-old man who is right-handed but who can use his left hand as well. He was admitted because of subarachnoid hemorrhage from an anterior communicating aneurysm. Because of postoperative spasm, an infarction in the distribution of the right anterior cerebral artery developed. He was totally unable to express himself vocally, but he could use written language quite well to express his ideas and had a good comprehension of spoken language. This clinical picture was considered that of an aphemia. After several weeks, his vocalization returned, but the initial output was still hypophonic.

  4. [Influence of early stimulation in cerebral palsy].

    Science.gov (United States)

    García-Navarro, M E; Tacoronte, M; Sarduy, I; Abdo, A; Galvizú, R; Torres, A; Leal, E

    Early stimulation is known to be useful, necessary treatment aimed at developing as much as possible the social psychophysical potential of any child at high environmental and/or biological risk. This group includes children with cerebral palsy, a disorder of the nervous system which may cause retardation in the processes of maturation of the central nervous system and be expressed from the earliest months of the child's life as retardation of psychomotor development. To show the efficiency of early stimulation in children diagnosed as having cerebral palsy and retardation of psychomotor development. A retrospective study was made of 20 children aged between 9 and 41 months with this diagnosis, in the hospital of CIREN (Cuba). They were treated for a period of 1 to 3 months by a multi-disciplinary team and participated in the programme for Early Stimulation. Assessment was made by the Neuropsychology Department at the start and end of the treatment period, using the first part of the Brunet-Lezine scale for the measurement of psychomotor development in early childhood. In all patients there was a favorable course and new abilities were acquired. There was better performance than before the treatment was started and accelerated rate of development during the period of treatment. Patients with cerebral palsy and psychomotor retardation benefit from application of a programme of Early Stimulation.

  5. Glycopyrrolate prevents extreme bradycardia and cerebral deoxygenation during electroconvulsive therapy

    DEFF Research Database (Denmark)

    Rasmussen, Peter; Andersson, John-Erik; Koch, Palle

    2007-01-01

    The stimulation phase of electroconvulsive therapy (ECT) induces bradycardia. We evaluated the effect of this bradycardia on cerebral perfusion and oxygenation by administration of the anticholinergic drug glycopyrrolate (Glp). Cerebral perfusion was estimated by transcranial ultrasound...... in the middle cerebral artery reporting the mean flow velocity (middle cerebral artery [MCA] V(mean)), and cerebral oxygenation was determined by near-infrared spectroscopy of the frontal lobe. Before ECT, heart rate (HR) was 84 beats min(-1) (66-113; median and range) and decreased to 17 (7-85) beats min(-1...... and oxygenation normalized over approximately 3 minutes, whereas the electroencephalogram was unaffected by Glp. The results demonstrate that ECT is associated with hemodynamic effects severe enough to affect cerebral oxygenation and perfusion, and that these effects can be attenuated by Glp treatment....

  6. Sleep slow-wave activity regulates cerebral glycolytic metabolism.

    Science.gov (United States)

    Wisor, Jonathan P; Rempe, Michael J; Schmidt, Michelle A; Moore, Michele E; Clegern, William C

    2013-08-01

    Non-rapid eye movement sleep (NREMS) onset is characterized by a reduction in cerebral metabolism and an increase in slow waves, 1-4-Hz oscillations between relatively depolarized and hyperpolarized states in the cerebral cortex. The metabolic consequences of slow-wave activity (SWA) at the cellular level remain uncertain. We sought to determine whether SWA modulates the rate of glycolysis within the cerebral cortex. The real-time measurement of lactate concentration in the mouse cerebral cortex demonstrates that it increases during enforced wakefulness. In spontaneous sleep/wake cycles, lactate concentration builds during wakefulness and rapid eye movement sleep and declines during NREMS. The rate at which lactate concentration declines during NREMS is proportional to the magnitude of electroencephalographic (EEG) activity at frequencies of cerebral SWA promotes a decline in the rate of glycolysis in the cerebral cortex. These results demonstrate a cellular energetic function for sleep SWA, which may contribute to its restorative effects on brain function.

  7. Enhanced cerebral perfusion during brief exposures to cyclic intermittent hypoxemia.

    Science.gov (United States)

    Liu, Xiaoli; Xu, Diqun; Hall, James R; Ross, Sarah; Chen, Shande; Liu, Howe; Mallet, Robert T; Shi, Xiangrong

    2017-12-01

    Cerebral vasodilation and increased cerebral oxygen extraction help maintain cerebral oxygen uptake in the face of hypoxemia. This study examined cerebrovascular responses to intermittent hypoxemia in eight healthy men breathing 10% O 2 for 5 cycles, each 6 min, interspersed with 4 min of room air breathing. Hypoxia exposures raised heart rate ( P hypoxemia. NEW & NOTEWORTHY Five bouts of 6-min intermittent hypoxia (IH) exposures to 10% O 2 progressively reduce arterial oxygen saturation ([Formula: see text]) to 67% without causing discomfort or distress. Cerebrovascular responses to hypoxemia are dynamically reset over the course of a single IH session, such that threshold and saturation for cerebral vasodilations occurred at lower [Formula: see text] and cerebral tissue oxygenation ([Formula: see text]) during the fifth vs. first hypoxia bouts. Cerebral oxygen extraction is augmented during acute hypoxemia, which compensates for decreased arterial O 2 content.

  8. The relation of breech presentation at term to cerebral palsy

    DEFF Research Database (Denmark)

    Krebs, L; Topp, M; Langhoff-Roos, J

    1999-01-01

    OBJECTIVE: To examine the relation between breech delivery and cerebral palsy, considering the influence of intrauterine growth, low Apgar score at birth, and mode of delivery. DESIGN: Register-based, case-control study. POPULATION: A cohort of infants with cerebral palsy born between 1979 and 1986...... in East Denmark, identified by linkage of the cerebral palsy register with the national birth register. Discharge letters from births of breech infants with cerebral palsy were reviewed. MAIN OUTCOME MEASURES: Presentation, mode of delivery, gestational age, birthweight, Apgar score, type of cerebral...... palsy, severity of handicap. RESULTS: Breech presentation at term was associated with a borderline significantly higher risk of cerebral palsy than vertex presentation (OR 1.56; 95% CI 0.9-2.4). Breech presentation infants more often had a lower Apgar score (

  9. The Coupling of Cerebral Metabolic Rate of Glucose and Cerebral Blood Flow In Vivo

    DEFF Research Database (Denmark)

    Hasselbalch, Steen; Paulson, Olaf Bjarne

    2012-01-01

    and metabolism was originally performed using the Kety-Schmidt method and this method still represent the gold standard by which subsequent methods have been evaluated. However, in its classical setting, the method overestimates cerebral blood flow. Studies of metabolic changes during activation must take......The energy supplied to the brain by metabolic substrate is largely utilized for maintaining synaptic transmission. In this regulation cerebral blood flow and glucose consumption is tightly coupled as well in the resting condition as during activation. Quantification of cerebral blood flow...... this into account, and subsequent methods for measurement of regional glucose metabolism must be corrected accordingly in order to allow reliable quantitative comparisons of metabolite changes in activation studies. For studies of regional metabolic changes during activation quantification poses further...

  10. Middle cerebral artery blood velocity and cerebral blood flow and O2 uptake during dynamic exercise

    DEFF Research Database (Denmark)

    Madsen, P L; Sperling, B K; Warming, T

    1993-01-01

    Results obtained by the 133Xe clearance method with external detectors and by transcranial Doppler sonography (TCD) suggest that dynamic exercise causes an increase of global average cerebral blood flow (CBF). These data are contradicted by earlier data obtained during less-well-defined conditions....... To investigate this controversy, we applied the Kety-Schmidt technique to measure the global average levels of CBF and cerebral metabolic rate of oxygen (CMRO2) during rest and dynamic exercise. Simultaneously with the determination of CBF and CMRO2, we used TCD to determine mean maximal flow velocity...... in the middle cerebral artery (MCA Vmean). For values of CBF and MCA Vmean a correction for an observed small drop in arterial PCO2 was carried out. Baseline values for global CBF and CMRO2 were 50.7 and 3.63 ml.100 g-1.min-1, respectively. The same values were found during dynamic exercise, whereas a 22% (P

  11. Rule Based Expert System for Cerebral Palsy Diagnosis

    OpenAIRE

    Borgohain, Rajdeep; Sanyal, Sugata

    2012-01-01

    The use of Artificial Intelligence is finding prominence not only in core computer areas, but also in cross disciplinary areas including medical diagnosis. In this paper, we present a rule based Expert System used in diagnosis of Cerebral Palsy. The expert system takes user input and depending on the symptoms of the patient, diagnoses if the patient is suffering from Cerebral Palsy. The Expert System also classifies the Cerebral Palsy as mild, moderate or severe based on the presented symptoms.

  12. Uncovering the role of IFNAR1 in Experimental Cerebral malaria

    OpenAIRE

    Ball, Elisabeth Ann

    2013-01-01

    Dissertation presented the Ph.D degree in Biology Cerebral malaria is a severe and fatal form of clinical Plasmodium falciparum infection, resulting in brain injury from a damaging cascade of vascular, inflammatory and immunological host responses. However progression to cerebral malaria can be modified by host genetic factors. This thesis work extensively reveals the role of Interferon type I receptor (IFNAR1) in the development of Experimental cerebral malaria, through ...

  13. Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

    OpenAIRE

    Sumbria, RK; Vasilevko, V.; Grigoryan, MM; Paganini-Hill, A; Kim, R; Cribbs, DH; Fisher, MJ

    2017-01-01

    Background Cerebral microbleeds (CMB) are MRI-demonstrable cerebral microhemorrhages (CMH) which commonly coexist with ischemic stroke. This creates a challenging therapeutic milieu, and a strategy that simultaneously protects the vessel wall and provides anti-thrombotic activity is an attractive potential approach. Phosphodiesterase 3A (PDE3A) inhibition is known to provide cerebral vessel wall protection combined with anti-thrombotic effects. As an initial step in the development of a thera...

  14. Paralisia cerebral hemiplégica e trombofilias geneticamente determinadas

    OpenAIRE

    Alexandre Castelo Branco Araujo

    2009-01-01

    Realizar uma análise detalhada relativa ao papel das trombofilias geneticamente determinadas como fatores predisponentes ao aparecimento de paralisia cerebral hemiplégica relacionada a acidente vascular cerebral isquêmico, abordando os principais aspectos conceituais, epidemiológicos e fisiopatológicos. O levantamento de artigos sobre o tema foi pesquisado nas bases de dados Medline, Lilacs, Embase, Cinahl e Cochrane, com palavras-chave acidente vascular cerebral, antitrombina, fator V Lei...

  15. Advances in the imaging of cerebral aneurysm inflammation

    Directory of Open Access Journals (Sweden)

    Michael R Levitt

    2015-06-01

    Full Text Available Cerebral aneurysm formation, growth and rupture are thought to be the result of a complex interaction between cerebrovascular hemodynamics and pathobiology. Recently, new evidence has emerged regarding the role of inflammation in the walls of cerebral aneurysms. Noninvasive methods to characterize the degree of inflammation in aneurysms could enable clinicians to estimate the risk of future aneurysm growth and rupture, influencing treatment. This review examines emerging techniques of imaging inflammatory biomarkers in cerebral aneurysms.

  16. Hypereosinophilia with Multiple Thromboembolic Cerebral Infarcts and Focal Intracerebral Hemorrhage

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Ju; Lee, Young Jun; Lee, Seung Ro; Park, Dong Woo; Kim, Hyun Young [Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2009-10-15

    We report a case of hypereosinophilia causing multiple areas of cerebral infarcts. A 52-year-old Korean man presented with dysarthria and weakness in both arms. A brain MRI revealed multiple acute infarcts in the distal border zone with focal intracerebral hemorrhage, whereas a cerebral angiogram was not remarkable. The eosinophil count was 5,500/{mu}L and was accompanied by elevated cardiac enzyme levels. The pattern of cerebral infarcts and laboratory results suggest a thromboembolic infarction associated with hypereosinophilia.

  17. Cerebral endothelial dysfunction in reversible cerebral vasoconstriction syndrome: a case-control study.

    Science.gov (United States)

    Choi, Hyun Ah; Lee, Mi Ji; Chung, Chin-Sang

    2017-12-01

    The aim of this study is to investigate cerebral endothelial dysfunction in patients with reversible cerebral vasoconstriction syndrome (RCVS). We prospectively recruited patients with RCVS, age-matched controls with episodic migraine, and age-matched healthy controls at Samsung Medical Center from Apr 2015 to Jul 2016. All participants underwent transcranial Doppler evaluation, with a breath-holding maneuver, for the evaluation of bilateral middle cerebral arteries (MCAs), posterior cerebral arteries (PCAs), and the basilar artery (BA). The breath-holding index (BHI) was used to measure cerebral endothelium-dependent vasodilation. Follow-up BHIs were recorded in selected patients with RCVS after 3 months. A total of 84 subjects were recruited for this study (n = 28 in each group of RCVS, episodic migraine, and healthy control; mean age, 49.8 years). The RCVS group showed lower BHIs in all basal arteries, in comparison to healthy controls (p < 0.001, 0.009 for bilateral MCAs, p < 0.001 and 0.028 for bilateral PCAs, and p = 0.060 for the BA). Compared to migraineurs, RCVS patients had lower BHIs only in the anterior circulation (p = 0.002 and 0.038 for bilateral MCAs; p = 0.069 and 0.247 for bilateral PCAs; p = 0.120 for the BA). Of the 10 patients who had follow-up BHIs at 3 months, 7 showed complete normalization, while three did not. Cerebral endothelial function is impaired in a widespread distribution in RCVS. Its role in the pathogenesis and clinical outcome of RCVS should be determined in further studies.

  18. Puerarin Attenuates Cerebral Damage by Improving Cerebral Microcirculation in Spontaneously Hypertensive Rats

    Directory of Open Access Journals (Sweden)

    Xu-Dong Wu

    2014-01-01

    Full Text Available Puerariae Lobatae Radix (Gegen in Chinese is the dried root of Pueraria lobata, a semiwoody, perennial, and leguminous vine native to China. Puerarin is one of the effective components of isoflavones isolated from the root of Pueraria lobata. Previous studies showed that extracts derived from the root of Pueraria lobata possessed antihypertensive effect. Our study is to investigate whether puerarin contributes to prevention of stroke by improving cerebral microcirculation in rats. Materials and Methods. Video microscopy and laser Doppler perfusion imaging on the pia mater were used to measure the diameter of microvessel and blood perfusion in 12-week old spontaneously hypertensive rats (SHRs and age-matched normotensive WKY rats. Histological alterations were observed by hematoxylin and eosin staining, and microvessel density in cerebral tissue was measured by immunohistochemical analysis with anti-Factor VIII antibody. Cell proliferation was detected by [3H]-TdR incorporation, and activities of p42/44 mitogen activated protein kinases (p42/44 MAPKs were detected by western blot analysis in cultured cerebral microvascular endothelial cells (MECs. Results. Intravenous injection of puerarin relaxed arterioles and increased the blood flow perfusion in the pia mater in SHRs. Puerarin treatment for 14 days reduced the blood pressure to a normal level in SHRs (P<0.05 and increased the arteriole diameter in the pia mater significantly as compared with vehicle treatment. Arteriole remodeling, edema, and ischemia in cerebral tissue were attenuated in puerarin-treated SHRs. Microvessel density in cerebral tissue was greater with puerarin than with vehicle treatment. Puerarin-treated MECs showed greater proliferation and p42/44 MAPKs activities than vehicle treatment. Conclusions. Puerarin possesses effects of antihypertension and stroke prevention by improved microcirculation in SHRs, which results from the increase in cerebral blood perfusion both by

  19. Puerarin attenuates cerebral damage by improving cerebral microcirculation in spontaneously hypertensive rats.

    Science.gov (United States)

    Wu, Xu-Dong; Wang, Chen; Zhang, Zhen-Ying; Fu, Yan; Liu, Feng-Ying; Liu, Xiu-Hua

    2014-01-01

    Puerariae Lobatae Radix (Gegen in Chinese) is the dried root of Pueraria lobata, a semiwoody, perennial, and leguminous vine native to China. Puerarin is one of the effective components of isoflavones isolated from the root of Pueraria lobata. Previous studies showed that extracts derived from the root of Pueraria lobata possessed antihypertensive effect. Our study is to investigate whether puerarin contributes to prevention of stroke by improving cerebral microcirculation in rats. Materials and Methods. Video microscopy and laser Doppler perfusion imaging on the pia mater were used to measure the diameter of microvessel and blood perfusion in 12-week old spontaneously hypertensive rats (SHRs) and age-matched normotensive WKY rats. Histological alterations were observed by hematoxylin and eosin staining, and microvessel density in cerebral tissue was measured by immunohistochemical analysis with anti-Factor VIII antibody. Cell proliferation was detected by [(3)H]-TdR incorporation, and activities of p42/44 mitogen activated protein kinases (p42/44 MAPKs) were detected by western blot analysis in cultured cerebral microvascular endothelial cells (MECs). Results. Intravenous injection of puerarin relaxed arterioles and increased the blood flow perfusion in the pia mater in SHRs. Puerarin treatment for 14 days reduced the blood pressure to a normal level in SHRs (P cerebral tissue were attenuated in puerarin-treated SHRs. Microvessel density in cerebral tissue was greater with puerarin than with vehicle treatment. Puerarin-treated MECs showed greater proliferation and p42/44 MAPKs activities than vehicle treatment. Conclusions. Puerarin possesses effects of antihypertension and stroke prevention by improved microcirculation in SHRs, which results from the increase in cerebral blood perfusion both by arteriole relaxation and p42/44 MAPKs-mediated angiogenesis.

  20. Angiopoietin-1 is associated with cerebral vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage

    Directory of Open Access Journals (Sweden)

    Pfausler Bettina

    2011-05-01

    Full Text Available Abstract Background Angiopoietin-1 (Ang-1 and -2 (Ang-2 are keyplayers in the regulation of endothelial homeostasis and vascular proliferation. Angiopoietins may play an important role in the pathophysiology of cerebral vasospasm (CVS. Ang-1 and Ang-2 have not been investigated in this regard so far. Methods 20 patients with subarachnoid hemorrhage (SAH and 20 healthy controls (HC were included in this prospective study. Blood samples were collected from days 1 to 7 and every other day thereafter. Ang-1 and Ang-2 were measured in serum samples using commercially available enzyme-linked immunosorbent assay. Transcranial Doppler sonography was performed to monitor the occurrence of cerebral vasospasm. Results SAH patients showed a significant drop of Ang-1 levels on day 2 and 3 post SAH compared to baseline and HC. Patients, who developed Doppler sonographic CVS, showed significantly lower levels of Ang-1 with a sustained decrease in contrast to patients without Doppler sonographic CVS, whose Ang-1 levels recovered in the later course of the disease. In patients developing cerebral ischemia attributable to vasospasm significantly lower Ang-1 levels have already been observed on the day of admission. Differences of Ang-2 between SAH patients and HC or patients with and without Doppler sonographic CVS were not statistically significant. Conclusions Ang-1, but not Ang-2, is significantly altered in patients suffering from SAH and especially in those experiencing CVS and cerebral ischemia. The loss of vascular integrity, regulated by Ang-1, might be in part responsible for the development of cerebral vasospasm and subsequent cerebral ischemia.

  1. Cerebral hemorrhagic infarction after radiation for pituitary adenoma

    Energy Technology Data Exchange (ETDEWEB)

    Ogaki, Satoko; Suzuki, Masatsune; Shimano, Hitoshi; Toyoshima, Hideo; Sone, Hirohito; Okuda, Yukichi; Yamada, Nobuhiro [Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine; Suzuki, Seiji; Suzuki, Hiroaki [National Hospital Tokyo Disaster Medical Center, Tachikawa (Japan)

    2002-10-01

    We report a case of cerebral hemorrhagic infarction after radiation for pituitary adenoma. A 55-year-old woman was hospitalized to check for aldosteronism, post-operative pituitary function, and recurrence of thyroid cancer. She had short-term memory disturbance beginning two months prior to admission. Brain MRI showed a T1 and T2 high intensity lesion of her left anterolateral thalamus. Brain MRA revealed a narrowing in her left middle cerebral artery. The abnormal brain lesion was diagnosed as cerebral hemorrhagic infarction. She had received radiation therapy for pituitary adenoma 20 years earlier. It was considered that her cerebral hemorrhagic infarction was caused by radiation therapy. (author)

  2. Cerebral toxoplasmosis in systemic lupus erythematosus following intravenous methylprednisolone.

    Science.gov (United States)

    Pagalavan, L; Kan, F K

    2011-03-01

    Cerebral toxoplasmosis is a rare complication of systemic lupus erythematosus (SLE). An 18 year old male student, newly diagnosed to have SLE, developed neurological symptoms two days after completing intravenous methylprednisolone. Computed tomography (CT) scan showed features consistent with a diagnosis of probable cerebral toxoplasmosis. He responded dramatically to antitoxoplasma therapy. To our knowledge, this is the first case report in the literature that presents a newly diagnosed SLE patient who rapidly developed cerebral toxoplasmosis following administration of intravenous methylprednisolone. Our case illustrates that this drug is potentially fatal and the importance of differentiating cerebral infection from neuropsychiatric lupus.

  3. Cerebral palsy-definition, classification, etiology and early diagnosis.

    Science.gov (United States)

    Sankar, Chitra; Mundkur, Nandini

    2005-10-01

    Cerebral palsy is a common neurodevelopmental condition encountered by pediatricians. The condition may present itself in many different clinical spectra. The etiological and risk factors are many and an awareness of the interplay of multiple factors in the causation of CP is crucial. In many cases, the cause of Cerebral palsy may not be apparent. Cerebral palsy is invariably associated with many deficits such as mental retardation, speech and language and oromotor problems. A thorough neurodevelopmental assessment of the child with Cerebral Palsy should include evaluation of associated deficits so that a comprehensive early intervention program an be planned and executed.

  4. Herpes Simplex Encephalitis Complicated by Cerebral Hemorrhage during Acyclovir Therapy.

    Science.gov (United States)

    Harada, Yukinori; Hara, Yuuta

    2017-01-01

    Herpes simplex encephalitis (HSE) can be complicated by adverse events in the acute phase. We herein present the case of a 71-year-old woman with HSE complicated by cerebral hemorrhage. She presented with acute deterioration of consciousness and fever and was diagnosed with HSE based on the detection of herpes simplex virus-1 in the cerebrospinal fluid by a polymerase chain reaction. The cerebral hemorrhage developed during acyclovir therapy; however, its diagnosis was delayed for 2 days. After the conservative treatment of the cerebral hemorrhage, the patient made a near-complete recovery. Cerebral hemorrhage should be considered as an acute-phase complication of HSE.

  5. Imaging findings and cerebral perfusion in arterial ischemic stroke due to transient cerebral arteriopathy in children; Achados de imagem e perfusao arterial cerebral em acidente vascular cerebral isquemico devido a arteriopatia transitoria em crianca

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa Junior, Alcino Alves, E-mail: alcinojr@uol.com.br [Departamento de Diagnostico por Imagem, Hospital Israelita Albert Einstein - HIAE, Sao Paulo, SP (Brazil); Ellovitch, Saada Resende de Souza [Neuropediatria, Hospital Israelita Albert Einstein - HIAE, Sao Paulo, SP (Brazil); Pincerato, Rita de Cassia Maciel [Hospital Samaritano, Sao Paulo, SP (Brazil)

    2012-04-15

    We report the case of a 4-year-old female child who developed an arterial ischemic stroke in the left middle cerebral artery territory, due to a proximal stenosis of the supraclinoid internal carotid artery, most probably related to transient cerebral arteriopathy of childhood. Computed tomography scan, magnetic resonance imaging, perfusion magnetic resonance and magnetic resonance angiography are presented, as well as follow-up by magnetic resonance and magnetic resonance angiography exams. Changes in cerebral perfusion and diffusion-perfusion mismatch call attention. As far as we know, this is the first report of magnetic resonance perfusion findings in transient cerebral arteriopathy. (author)

  6. Bilateral cerebral hemispheric infarction associated with sildenafil citrate (Viagra) use.

    Science.gov (United States)

    Kim, K-K; Kim, D G; Ku, Y H; Lee, Y J; Kim, W-C; Kim, O J; Kim, H S

    2008-03-01

    Sildenafil citrate (Viagra) is one of the frequently prescribed drugs for men with erectile dysfunction. We describe a 52-year-old man with bilateral middle cerebral artery (MCA) territory infarction after sildenafil use. He ingested 100 mg of sildenafil and about 1 h later, he complained of chest discomfort, palpitation and dizziness followed by mental obtundation, global aphasia and left hemiparesis. Brain magnetic resonance imaging documented acute bilateral hemispheric infarction, and cerebral angiography showed occluded bilateral MCA. Despite significant bilateral MCA stenosis and cerebral infarction, systemic hypotension persisted for a day. We presume that cerebral infarction was caused by cardioembolism with sildenafil use.

  7. À propos du lexique juridique en ancien français avant le 13e siècle : la Règle de saint Benoît et le Perceval de Chrétien de Troyes

    Directory of Open Access Journals (Sweden)

    Schauwecker Yela

    2012-07-01

    Full Text Available La plus ancienne traduction de la {em Règle} de saint Benoît en franc{c}ais, rédigée en dialecte picard-wallon, date de la première moitié ou du milieu du {sc xii}$^{m e}$~siècle. On veut montrer que son auteur, pour qui le changement de langue, n'est pas le premier objectif s'efforce de transférer le texte de son milieu originel de l'Antiquité tardive dans le monde chevaleresque-féodal du {sc xii}$^{m e}$~siècle. Même sans nécessité apparente, quand il a eu à sa disposition l'équivalent du mot employé dans la {em Regula}, il substitue aux mots latins des termes juridiques et féodaux franc{c}ais. par Son texte, en tant que document de droit pour les moines, devient ainsi une source de vocabulaire juridique franc{c}ais avant le {sc xiii}$^{m e}$~siècle, c'est-à-dire dans un temps où les documents juridiques en langue vulgaire sont extrêmement rares. Cela est dû au fait que la justice, dans le Nord, fondée sur des coutumes, utilisait la langue vernaculaire à l'oral. La terminologie juridique franc{c}aise est bien enracinée dans la langue courante de l'époque~: leur insertion dans les Lais et les Chansons de geste en fait preuve. Mais cette terminologie est souvent méconnue par la lexicographie traditionnelle de l'ancien franc{c}ais, en raison des contextes littéraires et figurés. par

  8. Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

    DEFF Research Database (Denmark)

    Sørensen, Niels Henrik Breiner; Secher, Niels H; Siebenmann, Christoph

    2012-01-01

    Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine...

  9. Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux.

    Science.gov (United States)

    Grüne, Frank; Kazmaier, Stephan; Sonntag, Hans; Stolker, Robert Jan; Weyland, Andreas

    2014-02-01

    Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair cerebral aerobic metabolism in patients undergoing intravenous anesthesia. Thirty male patients scheduled for coronary surgery were included in a prospective, controlled crossover trial. Measurements were performed under fentanyl-midazolam anesthesia in a randomized sequence aiming at partial pressures of carbon dioxide of 30 and 50 mmHg. Endpoints were CBF, blood flow velocity in the middle cerebral artery, and cerebral metabolic rates for oxygen, glucose, and lactate. Global CBF was measured using a modified Kety-Schmidt technique with argon as inert gas tracer. CBF velocity of the middle cerebral artery was recorded by transcranial Doppler sonography. Data were presented as mean (SD). Two-sided paired t tests and one-way ANOVA for repeated measures were used for statistical analysis. Moderate hyperventilation significantly decreased CBF by 60%, blood flow velocity by 41%, cerebral oxygen delivery by 58%, and partial pressure of oxygen of the jugular venous bulb by 45%. Cerebral metabolic rates for oxygen and glucose remained unchanged; however, net cerebral lactate efflux significantly increased from -0.38 (2.18) to -2.41(2.43) µmol min 100 g. Moderate hyperventilation, when compared with moderate hypoventilation, in patients with cardiovascular disease undergoing intravenous anesthesia increased net cerebral lactate efflux and markedly reduced CBF and partial pressure of oxygen of the jugular venous bulb, suggesting partial impairment of cerebral aerobic metabolism at clinically relevant levels of hypocapnia.

  10. The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial

    Science.gov (United States)

    2017-07-05

    Cerebral Hemorrhage; Stroke; Hypertension; Diabetes; Anticoagulant-induced Bleeding; Cerebral Vascular Disorder; Brain Disorder; Hemorrhage; Intracranial Hemorrhages; Cardiovascular Diseases; Central Nervous System Diseases

  11. Bedside Diagnosis of Mitochondrial Dysfunction After Malignant Middle Cerebral Artery Infarction

    DEFF Research Database (Denmark)

    Nielsen, T H; Schalén, W; Ståhl, N

    2014-01-01

    The study explores whether the cerebral biochemical pattern in patients treated with hemicraniectomy after large middle cerebral artery infarcts reflects ongoing ischemia or non-ischemic mitochondrial dysfunction....

  12. Microsurgery Simulator of Cerebral Aneurysm Clipping with Interactive Cerebral Deformation Featuring a Virtual Arachnoid.

    Science.gov (United States)

    Shono, Naoyuki; Kin, Taichi; Nomura, Seiji; Miyawaki, Satoru; Saito, Toki; Imai, Hideaki; Nakatomi, Hirofumi; Oyama, Hiroshi; Saito, Nobuhito

    2017-08-01

    A virtual reality simulator for aneurysmal clipping surgery is an attractive research target for neurosurgeons. Brain deformation is one of the most important functionalities necessary for an accurate clipping simulator and is vastly affected by the status of the supporting tissue, such as the arachnoid membrane. However, no virtual reality simulator implementing the supporting tissue of the brain has yet been developed. To develop a virtual reality clipping simulator possessing interactive brain deforming capability closely dependent on arachnoid dissection and apply it to clinical cases. Three-dimensional computer graphics models of cerebral tissue and surrounding structures were extracted from medical images. We developed a new method for modifiable cerebral tissue complex deformation by incorporating a nonmedical image-derived virtual arachnoid/trabecula in a process called multitissue integrated interactive deformation (MTIID). MTIID made it possible for cerebral tissue complexes to selectively deform at the site of dissection. Simulations for 8 cases of actual clipping surgery were performed before surgery and evaluated for their usefulness in surgical approach planning. Preoperatively, each operative field was precisely reproduced and visualized with the virtual brain retraction defined by users. The clear visualization of the optimal approach to treating the aneurysm via an appropriate arachnoid incision was possible with MTIID. A virtual clipping simulator mainly focusing on supporting tissues and less on physical properties seemed to be useful in the surgical simulation of cerebral aneurysm clipping. To our knowledge, this article is the first to report brain deformation based on supporting tissues.

  13. Aspergilose cerebral em paciente imunocompetente Cerebral Aspergillus abscess in immunocompetent patient

    Directory of Open Access Journals (Sweden)

    Geraldo Pianetti Filho

    2005-12-01

    Full Text Available Descrevemos um caso raro de aspergilose cerebral, como complicação de cirurgia para aneurisma cerebral, em paciente imunocompetente, e com sucesso no tratamento. A paciente, de 40 anos, havia sido submetida a craniotomia para clipagem de aneurisma da artéria pericalosa. Após cinco meses, no sitio cirúrgico, surgiram múltiplos abscessos por Aspergillus sp. Foram necessárias duas craniotomias para a retirada da massa fúngica e uso de anfotericina B. Após 14 anos de acompanhamento, a evolução mostra resolução da aspergilose, sem seqüela. O tratamento do abscesso cerebral por Aspergilus exige acompanhamento clínico contínuo, repetidas drenagens cirúrgicas intracranianas e o uso de anfotericina B no tratamento medicamentoso.We report an unusual case of brain aspergillosis with multiple recurrent abscess in a 40 years-old immunocompetent woman, with good therapeutical outcome. The patient presented a subaracnoid hemorhage caused by a ruptured pericalosal artery aneurysm and was submitted to a craniotomy for aneurysm surgery. Five months later, she developed multiple Aspergillus cerebral abscess. Two craniotomies and amphotericin B became necessary during treatment. Fourteen years later, she is asymptomatic. Treatment of brain aspergillosis abscess implied the combination of both surgical and drug therapy with amphotericin B.

  14. Puerarin Attenuates Cerebral Damage by Improving Cerebral Microcirculation in Spontaneously Hypertensive Rats

    Science.gov (United States)

    Wu, Xu-Dong; Wang, Chen; Zhang, Zhen-Ying; Fu, Yan; Liu, Feng-Ying; Liu, Xiu-Hua

    2014-01-01

    Puerariae Lobatae Radix (Gegen in Chinese) is the dried root of Pueraria lobata, a semiwoody, perennial, and leguminous vine native to China. Puerarin is one of the effective components of isoflavones isolated from the root of Pueraria lobata. Previous studies showed that extracts derived from the root of Pueraria lobata possessed antihypertensive effect. Our study is to investigate whether puerarin contributes to prevention of stroke by improving cerebral microcirculation in rats. Materials and Methods. Video microscopy and laser Doppler perfusion imaging on the pia mater were used to measure the diameter of microvessel and blood perfusion in 12-week old spontaneously hypertensive rats (SHRs) and age-matched normotensive WKY rats. Histological alterations were observed by hematoxylin and eosin staining, and microvessel density in cerebral tissue was measured by immunohistochemical analysis with anti-Factor VIII antibody. Cell proliferation was detected by [3H]-TdR incorporation, and activities of p42/44 mitogen activated protein kinases (p42/44 MAPKs) were detected by western blot analysis in cultured cerebral microvascular endothelial cells (MECs). Results. Intravenous injection of puerarin relaxed arterioles and increased the blood flow perfusion in the pia mater in SHRs. Puerarin treatment for 14 days reduced the blood pressure to a normal level in SHRs (P antihypertension and stroke prevention by improved microcirculation in SHRs, which results from the increase in cerebral blood perfusion both by arteriole relaxation and p42/44 MAPKs-mediated angiogenesis. PMID:24715930

  15. Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat

    DEFF Research Database (Denmark)

    Spray, Stine; Johansson, Sara E; Edwards, Alistair V G

    2017-01-01

    . The proteomic profile of the isolated cerebral microvasculature 72 h after GCI (compared to sham) indicated that the main expressional changes could be divided into nine categories: (1) cellular respiration, (2) remodelling of the extracellular matrix, (3) decreased contractile phenotype, (4) clathrin...

  16. Cerebral oximetry improves detection of sickle cell patients at risk for nocturnal cerebral hypoxia.

    Science.gov (United States)

    Raj, Ashok B; O'brien, Louise M; Bertolone, Salvatore J; Gozal, David; Edmonds, Harvey L

    2006-11-01

    We previously used cerebral oximetry to identify low cerebral venous oxygen saturation in waking children with sickle cell disease (SCD). Because arterial oxyhemoglobin desaturation is common during sleep in SCD patients, this study compared both waking and sleeping systemic arterial and cerebral venous oxygenation dynamics in children with and without SCD. Seventeen African-American (AA) children with homozygous SCD [8 (4-15) years; 29% male; normal transcranial Doppler velocities] were compared with a control cohort (CON) comprised of six healthy AA children [9 (4-16) years, 33% male]. Standard all-night polysomnographic recordings were performed, including measurement of arterial oxygen saturation by pulse oximetry (SpO(2)). Regional cerebral oxygen saturation (rSO(2)) was measured non-invasively with cerebral oximetry. Intra-cohort comparisons examined the influence of sleep on SpO(2) and rSO(2) in the subjects. Inter-cohort comparisons of SpO(2), rSO(2,) and the rSO(2)/SpO(2) ratio assessed the impact of SCD on systemic and cerebral oxygenation during wakefulness and sleep. Cohort differences in SpO(2) were not statistically significant in either wakefulness or sleep. However, only in the SCD cohort was the magnitude of SpO(2) change statistically significant (P = 0.002). In contrast, both waking and sleep rSO(2) cohort median values did differ significantly [awake: CON 76 (67-86) vs. SCD 62 (58-71), P = 0.01; sleep: CON 65 (60-77) vs. SCD 55 (48-61), P = 0.01)]. The waking rSO(2)/SpO(2) ratio was also significantly lower in the SCD group [CON 0.78 (0.68-0.88) vs. SCD of 0.66 (0.61-0.72); P = 0.015]. During sleep, the ratio was also significantly lower in the SCD group [CON 0.71 (0.66-0.81) vs. SCD 0.59 (0.52-0.65); P = 0.011]. Our findings suggest that SCD patients may be at increased risk of cerebral hypoxia during both wakefulness and sleep.

  17. Paralisia cerebral, novas perspectivas terapêuticas Cerebral palsy, new therapeutic possibilities

    Directory of Open Access Journals (Sweden)

    Newra Tellechea Rotta

    2002-08-01

    Full Text Available Objetivo: a revisão da paralisia cerebral tem como objetivo oferecer ao pediatra informações atualizadas sobre o diagnóstico e tratamento. Fontes dos dados: foram utilizados dados de revisão bibliográfica não sistematizada e da experiência no atendimento dos pacientes da Unidade de Neurologia do Serviço de Pediatria do HCPA-UFRGS. Síntese dos dados: o diagnóstico e tratamento da paralisia cerebral é multidisciplinar. Ao lado do sintoma principal motor, estão os sintomas associados que requerem igual atenção. Os exames de neuroimagem são importantes para melhor localizar a lesão, e mostrar sua extensão e características. O EEG auxilia no diagnóstico das epilepsias associadas. O tratamento principal é fisioterápico, auxiliado pelo tratamento da espasticidade, com antiespásticos orais, ou com toxina botulínica injetável. O tratamento de epilepsia secundária varia de acordo com o tipo de crise. Conclusões: o pediatra é o primeiro médico a entrar em contato com a criança com paralisia cerebral, e deve estar apto para reconhecer precocemente os desvios do desenvolvimento, orientar o manejo e, dentro das possibilidades e necessidades, encaminhar ao especialista.Objective: to provide pediatrician with updated information about diagnoses and treatment of cerebral palsy. This articles aims at supplying pediatricians with tools that will help them diagnose and treat cerebral palsy. Sources: non-systematic review of literature combined with personal experience at the Neurology Unit of Pediatrics Service of Hospital de Clínicas de Porto Alegre - Universidade Federal do Rio Grande do Sul. Summary of the findings: the cerebral palsy diagnosis and treatment are based on multidisciplinary clinical exam, EEG, CT and MR. Conclusions: pediatricians are the first physician that see the patient with cerebral palsy. Thus, they should be able to diagnose an treat it.

  18. Brain endothelial dysfunction in cerebral adrenoleukodystrophy.

    Science.gov (United States)

    Musolino, Patricia L; Gong, Yi; Snyder, Juliet M T; Jimenez, Sandra; Lok, Josephine; Lo, Eng H; Moser, Ann B; Grabowski, Eric F; Frosch, Matthew P; Eichler, Florian S

    2015-11-01

    See Aubourg (doi:10.1093/awv271) for a scientific commentary on this article.X-linked adrenoleukodystrophy is caused by mutations in the ABCD1 gene leading to accumulation of very long chain fatty acids. Its most severe neurological manifestation is cerebral adrenoleukodystrophy. Here we demonstrate that progressive inflammatory demyelination in cerebral adrenoleukodystrophy coincides with blood-brain barrier dysfunction, increased MMP9 expression, and changes in endothelial tight junction proteins as well as adhesion molecules. ABCD1, but not its closest homologue ABCD2, is highly expressed in human brain microvascular endothelial cells, far exceeding its expression in the systemic vasculature. Silencing of ABCD1 in human brain microvascular endothelial cells causes accumulation of very long chain fatty acids, but much later than the immediate upregulation of adhesion molecules and decrease in tight junction proteins. This results in greater adhesion and transmigration of monocytes across the endothelium. PCR-array screening of human brain microvascular endothelial cells after ABCD1 silencing revealed downregulation of both mRNA and protein levels of the transcription factor c-MYC (encoded by MYC). Interestingly, MYC silencing mimicked the effects of ABCD1 silencing on CLDN5 and ICAM1 without decreasing the levels of ABCD1 protein itself. Together, these data demonstrate that ABCD1 deficiency induces significant alterations in brain endothelium via c-MYC and may thereby contribute to the increased trafficking of leucocytes across the blood-brain barrier as seen in cerebral adrenouleukodystrophy. © The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Neuroimaging of cerebral vasculitis; Bildgebung zerebraler Vaskulitiden

    Energy Technology Data Exchange (ETDEWEB)

    Wengenroth, M. [Universitaetsklinikum Schleswig-Holstein, Campus Luebeck, Institut fuer Neuroradiologie, Luebeck (Germany); Klinikum der Ludwig-Maximilians-Universitaet, Institut fuer klinische Radiologie, Muenchen (Germany); Saam, T. [Klinikum der Ludwig-Maximilians-Universitaet, Institut fuer klinische Radiologie, Muenchen (Germany); Haehnel, S. [Universitaetsklinikum Heidelberg, Abteilung Neuroradiologie, Heidelberg (Germany)

    2016-01-15

    Cerebral vasculitis can have a variety of origins. Furthermore, there are no vasculitis-specific symptoms or imaging signs and vasculitis of the CNS can mimic many other neurological diseases, which require different treatment approaches. Thus, the clinical and radiological diagnosis of cerebral vasculitis is challenging. Magnetic resonance imaging (MRI) and MR angiography (MRA) should be the radiological imaging methods of choice to assess the degree of parenchymal damage and to detect vessel wall changes. If the results are unclear digital subtraction angiography (DSA) should be pursued in order to also detect changes in medium sized vessels. Vasculitis of small vessels cannot be detected by vascular imaging and requires brain or leptomeningeal biopsy. In this review we present the current diagnostic approach and a variety of imaging findings in cerebral vasculitis and discuss the main radiological differential diagnoses. (orig.) [German] Die zerebrale Vaskulitis kann viele Ursachen haben. Daher ist die klinische und radiologische Diagnose schwierig, auch weil es etliche vaskulitistypische Symptome und MR-Befunde bei anderen Erkrankungen gibt. Die ZNS-Vaskulitis kann zahlreiche andere neurologische Erkrankungen imitieren, die unterschiedlicher Therapie beduerfen. MRT und MR-Angiographie (MRA) sind die Verfahren der Wahl, mit denen die radiologische Diagnostik begonnen werden sollte, um den Parenchymschaden und den Gefaessbefall zu beurteilen. Bei unklaren Befunden kann eine digitale Subtraktionsangiographie (DSA) ergaenzt werden, um auch mittelgrosse Gefaesse beurteilen zu koennen. Der Befall kleiner Gefaesse kann nur bioptisch nachgewiesen werden. In der folgenden Uebersicht stellen wir das diagnostische Herangehen bei zerebraler Vaskulitis vor, praesentieren zahlreiche Befunde und diskutieren die wichtigsten radiologischen Differenzialdiagnosen. (orig.)

  20. Unique double recurrence of cerebral arteriovenous malformation.

    Science.gov (United States)

    Nagm, Alhusain; Horiuchi, Tetsuyoshi; Ichinose, Shunsuke; Hongo, Kazuhiro

    2015-09-01

    Surgically treated patients with arteriovenous malformations (AVMs) are considered cured when the postoperative angiogram proves complete resection. However, despite no residual nidus or early draining vein on postoperative angiogram, rare instances of AVM recurrence have been reported in adults. In this paper, the authors present a case of a 24-year-old woman with asymptomatic double recurrence of her cerebral AVM after angiographically proven complete resection. To the authors' knowledge, this patient represents the first case with double de novo asymptomatic recurrence of Spetzler-Martin grade I AVM. Also, she represents the first case with unique AVM criteria in each recurrence.