WorldWideScience

Sample records for variation nlte line

  1. A Grid of NLTE Corrections for Sulphur Lines in Atmospheres of Cool Stars for the Gaia-ESO Survey

    Science.gov (United States)

    Korotin, S.; Andrievsky, S.; Caffau, E.; Bonifacio, P.

    2017-06-01

    To derive sulfur abundance in a large amount of the stars from Gaia-ESO survey we calculated grid of theoretical line equivalent widths of 8th multiplet. We show that NLTE effects increase equivalent widths of the sulfur lines. NLTE corrections for this multiplet are not too large (about 0.15 dex) in contrast with corrections for other sulfur multiplets.

  2. A Si I atomic model for NLTE spectropolarimetric diagnostics of the 10 827 Å line

    Science.gov (United States)

    Shchukina, N. G.; Sukhorukov, A. V.; Trujillo Bueno, J.

    2017-07-01

    Aims: The Si I 10 827 Å line is commonly used for spectropolarimetric diagnostics of the solar atmosphere. First, we aim at quantifying the sensitivity of the Stokes profiles of this line to non-local thermodynamic equilibrium (NLTE) effects. Second, we aim at facilitating NLTE diagnostics of the Si I 10 827 Å line. To this end, we propose the use of a relatively simple silicon model atom, which allows a fast and accurate computation of Stokes profiles. The NLTE Stokes profiles calculated using this simple model atom are very similar to those obtained via the use of a very comprehensive silicon model atom. Methods: We investigate the impact of the NLTE effects on the Si I 10 827 Å line by means of multilevel radiative transfer calculations in a three-dimensional (3D) model atmosphere taken from a state-of-the-art magneto-convection simulation with small-scale dynamo action. We calculate the emergent Stokes profiles for this line at the solar disk center and for every vertical column of the 3D snapshot model, neglecting the effects of horizontal radiative transfer. Results: We find significant departures from LTE in the Si I 10 827 Å line, not only in the intensity but also in the linearly and circularly polarized profiles. At wavelengths around 0.1 Å, where most of the Stokes Q, U, and V peaks of the Si I 10 827 Å line occur, the differences between the NLTE and LTE profiles are comparable with the Stokes amplitudes themselves. The deviations from LTE increase with increasing Stokes Q, U, and V signals. Concerning the Stokes V profiles, the NLTE effects correlate with the magnetic field strength in the layers where such circular polarization signals are formed. Conclusions: The NLTE effects should be taken into account when diagnosing the emergent Stokes I profiles as well as the Stokes Q, U, and V profiles of the Si I 10 827 Å line. The sixteen-level silicon model atom proposed here, with six radiative bound-bound transitions, is suitable to account for the

  3. NLTE ANALYSIS OF HIGH-RESOLUTION H -BAND SPECTRA. I. NEUTRAL SILICON

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Junbo; Shi, Jianrong; Liu, Chao [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, A20 Datun Road, Chaoyang District, Beijing 100012 (China); Pan, Kaike [Apache Point Observatory and New Mexico State University, P.O. Box 59, Sunspot, NM, 88349-0059 (United States); Prieto, Carlos Allende, E-mail: sjr@bao.ac.cn [Instituto de Astrofísica de Canarias, E-38205 La Laguna, Tenerife (Spain)

    2016-12-20

    We investigated the reliability of our silicon atomic model and the influence of non-local thermodynamical equilibrium (NLTE) on the formation of neutral silicon (Si i) lines in the near-infrared (near-IR) H -band. We derived the differential Si abundances for 13 sample stars with high-resolution H -band spectra from the Apache Point Observatory Galactic Evolution Experiment (APOGEE), as well as from optical spectra, both under local thermodynamical equilibrium (LTE) and NLTE conditions. We found that the differences between the Si abundances derived from the H -band and from optical lines for the same stars are less than 0.1 dex when the NLTE effects are included, and that NLTE reduces the line-to-line scatter in the H -band spectra for most sample stars. These results suggest that our Si atomic model is appropriate for studying the formation of H -band Si lines. Our calculations show that the NLTE corrections of the Si i H -band lines are negative, i.e., the final Si abundances will be overestimated in LTE. The corrections for strong lines depend on surface gravity, and tend to be larger for giants, reaching ∼−0.2 dex in our sample, and up to ∼−0.4 dex in extreme cases of APOGEE targets. Thus, the NLTE effects should be included in deriving silicon abundances from H -band Si i lines, especially for the cases where only strong lines are available.

  4. NLTE ANALYSIS OF HIGH-RESOLUTION H -BAND SPECTRA. II. NEUTRAL MAGNESIUM

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Junbo; Shi, Jianrong; Liu, Chao [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, A20 Datun Road, Chaoyang District, Beijing 100012 (China); Pan, Kaike [Apache Point Observatory and New Mexico State University, P.O. Box 59, Sunspot, NM 88349-0059 (United States); Prieto, Carlos Allende, E-mail: sjr@bao.ac.cn [Instituto de Astrofísica de Canarias, E-38205 La Laguna, Tenerife (Spain)

    2017-01-20

    Aiming at testing the validity of our magnesium atomic model and investigating the effects of non-local thermodynamical equilibrium (NLTE) on the formation of the H -band neutral magnesium lines, we derive the differential Mg abundances from selected transitions for 13 stars either adopting or relaxing the assumption of local thermodynamical equilibrium (LTE). Our analysis is based on high-resolution and high signal-to-noise ratio H -band spectra from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) and optical spectra from several instruments. The absolute differences between the Mg abundances derived from the two wavelength bands are always less than 0.1 dex in the NLTE analysis, while they are slightly larger for the LTE case. This suggests that our Mg atomic model is appropriate for investigating the NLTE formation of the H -band Mg lines. The NLTE corrections for the Mg i H -band lines are sensitive to the surface gravity, becoming larger for smaller log g values, and strong lines are more susceptible to departures from LTE. For cool giants, NLTE corrections tend to be negative, and for the strong line at 15765 Å they reach −0.14 dex in our sample, and up to −0.22 dex for other APOGEE stars. Our results suggest that it is important to include NLTE corrections in determining Mg abundances from the H -band Mg i transitions, especially when strong lines are used.

  5. Observations and NLTE modeling of Ellerman bombs

    Science.gov (United States)

    Berlicki, A.; Heinzel, P.

    2014-07-01

    Context. Ellerman bombs (EBs) are short-lived, compact, and spatially well localized emission structures that are observed well in the wings of the hydrogen Hα line. EBs are also observed in the chromospheric CaII lines and in UV continua as bright points located within active regions. Hα line profiles of EBs show a deep absorption at the line center and enhanced emission in the line wings with maxima around ±1 Å from the line center. Similar shapes of the line profiles are observed for the CaII IR line at 8542 Å. In CaII H and K lines the emission peaks are much stronger, and EBs emission is also enhanced in the line center. Aims: It is generally accepted that EBs may be considered as compact microflares located in lower solar atmosphere that contribute to the heating of these low-lying regions, close to the temperature minimum of the atmosphere. However, it is still not clear where exactly the emission of EBs is formed in the solar atmosphere. High-resolution spectrophotometric observations of EBs were used for determining of their physical parameters and construction of semi-empirical models. Obtained models allow us to determine the position of EBs in the solar atmosphere, as well as the vertical structure of the activated EB atmosphere Methods: In our analysis we used observations of EBs obtained in the Hα and CaII H lines with the Dutch Open Telescope (DOT). These one-hour long simultaneous sequences obtained with high temporal and spatial resolution were used to determine the line emissions. To analyze them, we used NLTE numerical codes for the construction of grids of 243 semi-empirical models simulating EBs structures. In this way, the observed emission could be compared with the synthetic line spectra calculated for all such models. Results: For a specific model we found reasonable agreement between the observed and theoretical emission and thus we consider such model as a good approximation to EBs atmospheres. This model is characterized by an

  6. NLTE4 Plasma Population Kinetics Database

    Science.gov (United States)

    SRD 159 NLTE4 Plasma Population Kinetics Database (Web database for purchase)   This database contains benchmark results for simulation of plasma population kinetics and emission spectra. The data were contributed by the participants of the 4th Non-LTE Code Comparison Workshop who have unrestricted access to the database. The only limitation for other users is in hidden labeling of the output results. Guest users can proceed to the database entry page without entering userid and password.

  7. Galactic evolution of copper in the light of NLTE computations

    Science.gov (United States)

    Andrievsky, S.; Bonifacio, P.; Caffau, E.; Korotin, S.; Spite, M.; Spite, F.; Sbordone, L.; Zhukova, A. V.

    2018-01-01

    We have developed a model atom for Cu with which we perform statistical equilibrium computations that allow us to compute the line formation of Cu I lines in stellar atmospheres without assuming local thermodynamic equilibrium (LTE). We validate this model atom by reproducing the observed line profiles of the Sun, Procyon and 11 metal-poor stars. Our sample of stars includes both dwarfs and giants. Over a wide range of stellar parameters, we obtain excellent agreement among different Cu I lines. The 11 metal-poor stars have iron abundances in the range - 4.2 ≤ [Fe/H] ≤ -1.4, the weighted mean of the [Cu/Fe] ratios is -0.22 dex, with a scatter of -0.15 dex. This is very different from the results from LTE analysis (the difference between NLTE and LTE abundances reaches 1 dex) and in spite of the small size of our sample, it prompts for a revision of the Galactic evolution of Cu.

  8. Impact of NLTE on research of early chemical enrichment of the dwarf galaxies

    Science.gov (United States)

    Mashonkina, Lyudmila

    2015-08-01

    The individual stars observed in the dwarf galaxies orbiting the Milky Way are presumably red giants. Their chemical abundances are commonly determined under the classical LTE assumption, despite its validity is questionable for atmospheres of giant, in particular, metal-poor stars. Exactly metal-poor objects are important for understanding the early chemical enrichment processes of the host galaxy and the onset of star formation. We selected a sample of the -4 factor of SH = 0.5 to the Drawinian rates of Fe+H collisions. Pronounced NLTE effects were calculated for lines of Na I and Al I resulting in up to 0.5 dex lower [Na/Fe] ratios and up to 0.65 dex higher [Al/Fe] ratios compared with the corresponding LTE values. For the six Scl stars, the scatter of data on Mg/Na is much smaller in NLTE, with the mean [Mg/Na] = 0.61 +- 0.11, than LTE, where [Mg/Na] = 0.42 +- 0.21. We computed a grid of the NLTE abundance corrections for an extensive list of the Ca I, Ti I-Ti II, and Fe I lines in the MARCS models of cool giants, 4000 K <= Teff <= 4750 K, 0.5 <= log g <= 2.5, -4 <= [M/H] <= 0.

  9. Morphological variation in maize inbred lines

    Directory of Open Access Journals (Sweden)

    Jiban Shrestha

    2014-05-01

    Full Text Available In order to identify morphological variation in maize inbred lines, one hundred five inbred lines were planted under randomized complete block design with two replications at research field of National Maize Research Program, Rampur, Chitwan, Nepal during summer season (March to June, 2010. Descriptive statistics and cluster analysis were done. The results revealed a wide range of morphological variation among the tested inbred lines. The inbred lines grouped in cluster 4 namely PUTU-13, L-9, RL-105, RL-197, RL-103, RML-9, RML-41, RL-165, RL-36, RL-76, RL-125, RL-30-3, L-6, RL-107, RL-174, RL-41, L-13, RML-76 and L-5 had 0.833 days anthesis-silking interval and earlier in flowering (tasseling in 54.50 days and silking in 55.33 days. Moreover they consisted of 1.16 plant aspect, 1.25 ear aspect, 33.08 cm tassel length and 13.5 tassel branch number. Among tested lines, the above inbred lines had better morphological traits, so it was concluded that they were good candidates for development of hybrids and synthetic varieties. DOI: http://dx.doi.org/10.3126/ije.v3i2.10521 International Journal of the Environment Vol.3(2 2014: 98-107

  10. 3D NLTE analysis of the most iron-deficient star, SMSS0313-6708

    Science.gov (United States)

    Nordlander, T.; Amarsi, A. M.; Lind, K.; Asplund, M.; Barklem, P. S.; Casey, A. R.; Collet, R.; Leenaarts, J.

    2017-01-01

    Context. Models of star formation in the early universe require a detailed understanding of accretion, fragmentation and radiative feedback in metal-free molecular clouds. Different simulations predict different initial mass functions of the first stars, ranging from predominantly low-mass (0.1-10 M⊙), to massive (10-100 M⊙), or even supermassive (100-1000 M⊙). The mass distribution of the first stars should lead to unique chemical imprints on the low-mass second and later generation metal-poor stars still in existence. The chemical composition of SMSS0313-6708, which has the lowest abundances of Ca and Fe of any star known, indicates it was enriched by a single massive supernova. Aims: The photospheres of metal-poor stars are relatively transparent in the UV, which may lead to large three-dimensional (3D) effects as well as departures from local thermodynamical equilibrium (LTE), even for weak spectral lines. If 3D effects and departures from LTE (NLTE) are ignored or treated incorrectly, errors in the inferred abundances may significantly bias the inferred properties of the polluting supernovae. We redetermine the chemical composition of SMSS0313-6708by means of the most realistic methods available, and compare the results to predicted supernova yields. Methods: A 3D hydrodynamical Staggermodel atmosphere and 3D NLTE radiative transfer were applied to obtain accurate abundances for Li, Na, Mg, Al, Ca and Fe. The model atoms employ realistic collisional rates, with no calibrated free parameters. Results: We find significantly higher abundances in 3D NLTE than 1D LTE by 0.8 dex for Fe, and 0.5 dex for Mg, Al and Ca, while Li and Na are unaffected to within 0.03 dex. In particular, our upper limit for [Fe/H] is now a factor ten larger, at [Fe/H] pair-instability supernovae.

  11. Observations and NLTE modeling of Ellerman bombs

    OpenAIRE

    Berlicki, Arkadiusz; Heinzel, Petr

    2014-01-01

    Ellerman bombs (EBs) are short-lived and compact structures that are observed well in the wings of the hydrogen H-alpha line. EBs are also observed in the chromospheric CaII lines and in UV continua. H-alpha line profiles of EBs show a deep absorption at the line center and enhanced emission in the line wings. Similar shapes of the line profiles are observed for the CaII IR line at 8542 ang. It is generally accepted that EBs may be considered as compact microflares located in lower solar atmo...

  12. Variational Bayesian Inference of Line Spectra

    DEFF Research Database (Denmark)

    Badiu, Mihai Alin; Hansen, Thomas Lundgaard; Fleury, Bernard Henri

    2017-01-01

    ) of the frequencies and computing expectations over them. Thus, we additionally capture and operate with the uncertainty of the frequency estimates. Aiming to maximize the model evidence, variational optimization provides analytic approximations of the posterior pdfs and also gives estimates of the additional...... not require parameter tuning, can easily include prior knowledge about the frequencies and provides approximate posterior pdfs based on which the uncertainty in line spectral estimation can be quantified. Simulation results show that accounting for the uncertainty of frequency estimates, rather than computing...... just point estimates, significantly improves the performance. The performance of VALSE is superior to that of state-of-the-art methods and closely approaches the Cramér-Rao bound computed for the true model order....

  13. Pulsations detected in the line profile variations of red giants : modelling of line moments, line bisector and line shape

    NARCIS (Netherlands)

    Hekker, S.; Aerts, C.; Ridder, J. de; Carrier, F.

    2006-01-01

    Context: So far, red giant oscillations have been studied from radial velocity and/or light curve variations, which reveal frequencies of the oscillation modes. To characterise radial and non-radial oscillations, line profile variations are a valuable diagnostic. Here we present for the first time a

  14. High-Fidelity Kinetics and Radiation Transport for NLTE Hypersonic Flows Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The modeling of NLTE hypersonic flows combines several disciplines: chemistry, kinetics, radiation transport, fluid mechanics, and surface science. No single code or...

  15. LINE-1 Retrotransposons: Mediators of Somatic Variation in Neuronal Genomes?

    OpenAIRE

    Singer, Tatjana; McConnell, Michael J.; Marchetto, Maria C. N.; Coufal, Nicole G.; Gage, Fred H.

    2010-01-01

    LINE-1 (L1) elements are retrotransposons that insert extra copies of themselves throughout the genome using a “copy and paste” mechanism. L1s have contributed ~20% to total human genome content and are able to influence chromosome integrity and gene expression upon reinsertion. Recent studies show that L1 elements are active and “jumping” during neuronal differentiation. New somatic L1 insertions may generate “genomic plasticity” in neurons by causing variation in genomic DNA sequences and b...

  16. Oxygen spectral line synthesis: 3D non-LTE with CO5BOLD hydrodynamical model atmospheres.

    Science.gov (United States)

    Prakapavičius, D.; Steffen, M.; Kučinskas, A.; Ludwig, H.-G.; Freytag, B.; Caffau, E.; Cayrel, R.

    In this work we present first results of our current project aimed at combining the 3D hydrodynamical stellar atmosphere approach with non-LTE (NLTE) spectral line synthesis for a number of key chemical species. We carried out a full 3D-NLTE spectrum synthesis of the oxygen IR 777 nm triplet, using a modified and improved version of our NLTE3D package to calculate departure coefficients for the atomic levels of oxygen in a CO5BOLD 3D hydrodynamical solar model atmosphere. Spectral line synthesis was subsequently performed with the Linfor3D code. In agreement with previous studies, we find that the lines of the oxygen triplet produce deeper cores under NLTE conditions, due to the diminished line source function in the line forming region. This means that the solar oxygen IR 777 nm lines should be stronger in NLTE, leading to negative 3D NLTE-LTE abundance corrections. Qualitatively this result would support previous claims for a relatively low solar oxygen abundance. Finally, we outline several further steps that need to be taken in order to improve the physical realism and numerical accuracy of our current 3D-NLTE calculations.

  17. Non-LTE line formation of Fe in late-type stars - IV. Modelling of the solar centre-to-limb variation in 3D

    Science.gov (United States)

    Lind, K.; Amarsi, A. M.; Asplund, M.; Barklem, P. S.; Bautista, M.; Bergemann, M.; Collet, R.; Kiselman, D.; Leenaarts, J.; Pereira, T. M. D.

    2017-07-01

    Our ability to model the shapes and strengths of iron lines in the solar spectrum is a critical test of the accuracy of the solar iron abundance, which sets the absolute zero-point of all stellar metallicities. We use an extensive 463-level Fe atom with new photoionization cross-sections for Fe I and quantum mechanical calculations of collisional excitation and charge transfer with neutral hydrogen; the latter effectively remove a free parameter that has hampered all previous line formation studies of Fe in non-local thermodynamic equilibrium (NLTE). For the first time, we use realistic 3D NLTE calculations of Fe for a quantitative comparison to solar observations. We confront our theoretical line profiles with observations taken at different viewing angles across the solar disc with the Swedish 1-m Solar Telescope. We find that 3D modelling well reproduces the observed centre-to-limb behaviour of spectral lines overall, but highlight aspects that may require further work, especially cross-sections for inelastic collisions with electrons. Our inferred solar iron abundance is log (ɛFe) = 7.48 ± 0.04 dex.

  18. NLTE Effects in Globular Cluster Integrated Light Spectra and Photometric Colors

    Science.gov (United States)

    Young, Mitchell; Short, C. Ian

    2017-01-01

    Our overall goal is to investigate the effect that modelling the atmospheres and spectra of Galactic globular cluster (GGCs) members in non-local thermodynamic equilibrium (NLTE) has on the integrated light (IL) spectrum, and the derivation of GGC ages and metallicities ([Fe/H] values) from IL photometric color and spectrum fitting. We create synthetic GGC populations and associated colour-magnitude diagrams (CMDs) using the Kroupa initial mass function (Kroupa, P., 2001, MNRAS, 322, 231-246) and the Teramo isochrones (Pietrinferni, A. et al, 2004, ApJ, 612, 168-190) with ages ranging from 9 to 15 Gyr, and [Fe/H] = -1.49 to -0.66 with α = +0.4. We investigate the dependence of predicted LTE and NLTE colors on the method and resolution of CMD discretization, and on the definition of representative stellar parameters in a discretized CMD.

  19. Variation in the Flaked Lines of Lathyrus Odoratus

    Indian Academy of Sciences (India)

    Somatic variation was also found in these forms. Flaked flower's bore at times dark-flaked sectors; the dark-flaked frequently had flaked parts. Rarely, bud variation occurred in the same way by Somatic mutation at the early stages of bud rudiments. More rarely the sport arose in the direction of self-coloured. We observed six.

  20. Computing NLTE Opacities -- Node Level Parallel Calculation

    Energy Technology Data Exchange (ETDEWEB)

    Holladay, Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-09-11

    Presentation. The goal: to produce a robust library capable of computing reasonably accurate opacities inline with the assumption of LTE relaxed (non-LTE). Near term: demonstrate acceleration of non-LTE opacity computation. Far term (if funded): connect to application codes with in-line capability and compute opacities. Study science problems. Use efficient algorithms that expose many levels of parallelism and utilize good memory access patterns for use on advanced architectures. Portability to multiple types of hardware including multicore processors, manycore processors such as KNL, GPUs, etc. Easily coupled to radiation hydrodynamics and thermal radiative transfer codes.

  1. Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines

    Directory of Open Access Journals (Sweden)

    Charles Addo-Quaye

    2017-02-01

    Full Text Available In order to leverage novel sequencing techniques for cloning genes in eukaryotic organisms with complex genomes, the false positive rate of variant discovery must be controlled for by experimental design and informatics. We sequenced five lines from three pedigrees of ethyl methanesulfonate (EMS-mutagenized Sorghum bicolor, including a pedigree segregating a recessive dwarf mutant. Comparing the sequences of the lines, we were able to identify and eliminate error-prone positions. One genomic region contained EMS mutant alleles in dwarfs that were homozygous reference sequences in wild-type siblings and heterozygous in segregating families. This region contained a single nonsynonymous change that cosegregated with dwarfism in a validation population and caused a premature stop codon in the Sorghum ortholog encoding the gibberellic acid (GA biosynthetic enzyme ent-kaurene oxidase. Application of exogenous GA rescued the mutant phenotype. Our method for mapping did not require outcrossing and introduced no segregation variance. This enables work when line crossing is complicated by life history, permitting gene discovery outside of genetic models. This inverts the historical approach of first using recombination to define a locus and then sequencing genes. Our formally identical approach first sequences all the genes and then seeks cosegregation with the trait. Mutagenized lines lacking obvious phenotypic alterations are available for an extension of this approach: mapping with a known marker set in a line that is phenotypically identical to starting material for EMS mutant generation.

  2. Accelerated complete-linearization method for calculating NLTE model stellar atmospheres

    Science.gov (United States)

    Hubeny, I.; Lanz, T.

    1992-01-01

    Two approaches to accelerating the method of complete linearization for calculating NLTE model stellar atmospheres are suggested. The first one, the so-called Kantorovich variant of the Newton-Raphson method, consists of keeping the Jacobi matrix of the system fixed, which allows us to calculate the costly matrix inversions only a few times and then keep them fixed during the subsequent computations. The second method is an application of the Ng acceleration. Both methods are extremely easy to implement with any model atmosphere code based on complete linearization. It is demonstrated that both methods, and especially their combination, yield a rapidly and globally convergent algorithm, which takes 2 to 5 times less computer time, depending on the model at hand and the required accuracy, than the ordinary complete linearization. Generally, the time gain is more significant for more complicated models. The methods were tested for a broad range of atmospheric parameters, and in all cases they exhibited similar behavior. Ng acceleration applied on the Kantorovich variant thus offers a significant improvement of the standard complete-linearization method, and may now be used for calculating relatively involved NLTE model stellar atmospheres.

  3. LINE-1 elements in structural variation and disease.

    Science.gov (United States)

    Beck, Christine R; Garcia-Perez, José Luis; Badge, Richard M; Moran, John V

    2011-01-01

    The completion of the human genome reference sequence ushered in a new era for the study and discovery of human transposable elements. It now is undeniable that transposable elements, historically dismissed as junk DNA, have had an instrumental role in sculpting the structure and function of our genomes. In particular, long interspersed element-1 (LINE-1 or L1) and short interspersed elements (SINEs) continue to affect our genome, and their movement can lead to sporadic cases of disease. Here, we briefly review the types of transposable elements present in the human genome and their mechanisms of mobility. We next highlight how advances in DNA sequencing and genomic technologies have enabled the discovery of novel retrotransposons in individual genomes. Finally, we discuss how L1-mediated retrotransposition events impact human genomes.

  4. Magnetic field dependent intensity variation in the hyperfine split Rb D1 and D2 lines

    Science.gov (United States)

    Hu, Jianping; Ummal Momeen, M.

    2017-11-01

    We present the variation of intensity in Doppler-free hyperfine lines for rubidium atoms with the application of magnetic field. Different polarization configurations have been studied systematically with varying magnetic fields. There is a significant increase in the intensity variation with applied magnetic field related to different polarization configurations. These variations are explained with the theoretical calculations. The calculations are performed by adopting Nakayama's four level model with the varying magnetic field induced transition probability.

  5. Massive genomic variation and strong selection in Arabidopsis thaliana lines from Sweden

    Science.gov (United States)

    Platzer, Alexander; Zhang, Qingrun; Vilhjálmsson, Bjarni J; Korte, Arthur; Nizhynska, Viktoria; Voronin, Viktor; Korte, Pamela; Sedman, Laura; Mandáková, Terezie; Lysak, Martin A; Seren, Ümit; Hellmann, Ines; Nordborg, Magnus

    2013-01-01

    Despite advances in sequencing, the goal of obtaining a comprehensive view of genetic variation in populations is still far from reached. We sequenced 180 lines of A. thaliana from Sweden to obtain as complete a picture as possible of variation in a single region. Whereas simple polymorphisms in the unique portion of the genome are readily identified, other polymorphisms are not. The massive variation in genome size identified by flow cytometry seems largely to be due to 45S rDNA copy number variation, with lines from northern Sweden having particularly large numbers of copies. Strong selection is evident in the form of long-range linkage disequilibrium (LD), as well as in LD between nearby compensatory mutations. Many footprints of selective sweeps were found in lines from northern Sweden, and a massive global sweep was shown to have involved a 700-kb transposition. PMID:23793030

  6. Regular orbital variations in the ultraviolet resonance lines of YZ Cnc

    Energy Technology Data Exchange (ETDEWEB)

    Drew, J.E.; Verbunt, F.

    1988-09-15

    Observations with the International Ultraviolet Explorer of the dwarf nova YZ Cnc show regular orbital variations in the line profiles of the ultraviolet resonance lines. The P Cygni profile of the C IV lambda 1549 line changes drastically from absorption-dominated to emission-dominated, during the three observed orbits in each of two observation shifts, separated by one day, shortly after an outburst maximum. Similar changes are visible in the N V lambda 1240 and Si IV lambda 1400 lines. It is argued that these observations indicate a strong deviation in the wind geometry from a spherical outflow pattern, and imply an asymmetry with respect to the disc rotation axis.

  7. Color variation in periodic Ag line arrays patterned by using electron-beam lithography.

    Science.gov (United States)

    Wei, D H; Cheng, K W; Yao, Y D; Hsu, S Y; Wei, P K; Huang, J H

    2010-07-01

    Periodic Ag line arrays with different line pitches from 500 nm to 950 nm on ITO coated glass substrates have been fabricated by using electron-beam lithography (EBL) technique for studying the color light guide in a display system. The patterned Ag line array is used as a light outcoupling and color-selection component due to the emission wavelength changed by the Ag line arrays with different periodic distances that could achieve color variation. We have demonstrated that the ITO coated glass substrates containing periodic Ag line arrays with varied line pitches can be used as a color filter in a display device. This means that with a proper metallic nanostructure layer, the red, green, and blue colors in a display system can be obtained without a traditional color filter for modern multi-applications of optoelectronic display devices.

  8. Analysis of Power Network for Line Reactance Variation to Improve Total Transmission Capacity

    Directory of Open Access Journals (Sweden)

    Ikram Ullah

    2016-11-01

    Full Text Available The increasing growth in power demand and the penetration of renewable distributed generations in competitive electricity market demands large and flexible capacity from the transmission grid to reduce transmission bottlenecks. The bottlenecks cause transmission congestion, reliability problems, restrict competition, and limit the maximum dispatch of low cost generations in the network. The electricity system requires efficient utilization of the current transmission capability to improve the Available Transfer Capability (ATC. To improve the ATC, power flow among the lines can be managed by using Flexible AC Transmission System (FACTS devices as power flow controllers, which alter the parameters of power lines. It is important to place FACTS devices on suitable lines to vary the reactance for improving Total Transmission Capacity (TTC of the network and provide flexibility in the power flow. In this paper a transmission network is analyzed based on line parameters variation to improve TTC of the interconnected system. Lines are selected for placing FACTS devices based on real power flow Performance Index (PI sensitivity factors. TTC is computed using the Repeated Power Flow (RPF method using the constraints of lines thermal limits, bus voltage limits and generator limits. The reactance of suitable lines, selected on the basis of PI sensitivity factors are changed to divert the power flow to other lines with enough transfer capacity available. The improvement of TTC using line reactance variation is demonstrated with three IEEE test systems with multi-area networks. The results show the variation of the selected lines’ reactance in improving TTC for all the test networks with defined contingency cases.

  9. Temporal Variation of Ca–K Line Profile of the Sun during the Solar ...

    Indian Academy of Sciences (India)

    Abstract. We obtained the Ca–K line profile of the Sun as a star since. 1969 at the Kodaikanal Observatory (KO) and analysis of the data showed the need to delineate the role of different chromospheric features to the variations of solar irradiance. We, therefore, initiated a new methodol- ogy to make observations of Ca–K ...

  10. Temporal Variation of Ca–K Line Profile of the Sun during the Solar ...

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... We obtained the Ca–K line profile of the Sun as a star since 1969 at the Kodaikanal Observatory (KO) and analysis of the data showed the need to delineate the role of different chromospheric features to the variations of solar irradiance. We, therefore, initiated a new methodology to make observations of ...

  11. Variation of Tower Footing Resistance on the Lightning Surge Propagation through Overhead Power Distribution Lines

    Directory of Open Access Journals (Sweden)

    MARIUT, E. L.

    2016-02-01

    Full Text Available This paper deals with the analysis of the effects of electromagnetic transients generated by lightning on power distribution lines, considering the influence of tower footing resistance variation. Both types of lightning stroke, direct and induced, are considered. The model of a 20 kV three-phase overhead power distribution line is performed considering a simple line circuit with triangle canopy and 50/8 mm2 Ol-Al conductors. The model of the power distribution line is done considering a Multistory tower model. New concepts regarding lightning assessment through Electromagnetic Transients program and Finite Element Method are implemented. The simulations are performed based on a time domain analysis, considering the lightning stroke as an electromagnetic perturbation within frequency range of 10-100 kHz. A contribution to value creation is the design of the Multistory tower model, used for electromagnetic transients analysis for medium voltage power distribution lines. Excepting previous research, current study was done by considering the variation of tower footing resistance of the tower, between 4-35 ohms. The novelty of the study is the analysis of the dependency determined by the variation of tower footing resistance on the lightning surge propagation through power distribution networks and subsequent consumers.

  12. Genetic architecture of variation in the lateral line sensory system of threespine sticklebacks.

    Science.gov (United States)

    Wark, Abigail R; Mills, Margaret G; Dang, Lam-Ha; Chan, Yingguang Frank; Jones, Felicity C; Brady, Shannon D; Absher, Devin M; Grimwood, Jane; Schmutz, Jeremy; Myers, Richard M; Kingsley, David M; Peichel, Catherine L

    2012-09-01

    Vertebrate sensory systems have evolved remarkable diversity, but little is known about the underlying genetic mechanisms. The lateral line sensory system of aquatic vertebrates is a promising model for genetic investigations of sensory evolution because there is extensive variation within and between species, and this variation is easily quantified. In the present study, we compare the lateral line sensory system of threespine sticklebacks (Gasterosteus aculeatus) from an ancestral marine and a derived benthic lake population. We show that lab-raised individuals from these populations display differences in sensory neuromast number, neuromast patterning, and groove morphology. Using genetic linkage mapping, we identify regions of the genome that influence different aspects of lateral line morphology. Distinct loci independently affect neuromast number on different body regions, suggesting that a modular genetic structure underlies the evolution of peripheral receptor number in this sensory system. Pleiotropy and/or tight linkage are also important, as we identify a region on linkage group 21 that affects multiple aspects of lateral line morphology. Finally, we detect epistasis between a locus on linkage group 4 and a locus on linkage group 21; interactions between these loci contribute to variation in neuromast pattern. Our results reveal a complex genetic architecture underlying the evolution of the stickleback lateral line sensory system. This study further uncovers a genetic relationship between sensory morphology and non-neural traits (bony lateral plates), creating an opportunity to investigate morphological constraints on sensory evolution in a vertebrate model system.

  13. Automatic Registration Method for Optical Remote Sensing Images with Large Background Variations Using Line Segments

    Directory of Open Access Journals (Sweden)

    Xiaolong Shi

    2016-05-01

    Full Text Available Image registration is an essential step in the process of image fusion, environment surveillance and change detection. Finding correct feature matches during the registration process proves to be difficult, especially for remote sensing images with large background variations (e.g., images taken pre and post an earthquake or flood. Traditional registration methods based on local intensity probably cannot maintain steady performances, as differences are significant in the same area of the corresponding images, and ground control points are not always available in many disaster images. In this paper, an automatic image registration method based on the line segments on the main shape contours (e.g., coastal lines, long roads and mountain ridges is proposed for remote sensing images with large background variations because the main shape contours can hold relatively more invariant information. First, a line segment detector called EDLines (Edge Drawing Lines, which was proposed by Akinlar et al. in 2011, is used to extract line segments from two corresponding images, and a line validation step is performed to remove meaningless and fragmented line segments. Then, a novel line segment descriptor with a new histogram binning strategy, which is robust to global geometrical distortions, is generated for each line segment based on the geometrical relationships,including both the locations and orientations of theremaining line segments relative to it. As a result of the invariance of the main shape contours, correct line segment matches will have similar descriptors and can be obtained by cross-matching among the descriptors. Finally, a spatial consistency measure is used to remove incorrect matches, and transformation parameters between the reference and sensed images can be figured out. Experiments with images from different types of satellite datasets, such as Landsat7, QuickBird, WorldView, and so on, demonstrate that the proposed algorithm is

  14. Donor Dependent Variations in Hematopoietic Differentiation among Embryonic and Induced Pluripotent Stem Cell Lines.

    Directory of Open Access Journals (Sweden)

    Olivier Féraud

    Full Text Available Hematopoiesis generated from human embryonic stem cells (ES and induced pluripotent stem cells (iPS are unprecedented resources for cell therapy. We compared hematopoietic differentiation potentials from ES and iPS cell lines originated from various donors and derived them using integrative and non-integrative vectors. Significant differences in differentiation toward hematopoietic lineage were observed among ES and iPS. The ability of engraftment of iPS or ES-derived cells in NOG mice varied among the lines with low levels of chimerism. iPS generated from ES cell-derived mesenchymal stem cells (MSC reproduce a similar hematopoietic outcome compared to their parental ES cell line. We were not able to identify any specific hematopoietic transcription factors that allow to distinguish between good versus poor hematopoiesis in undifferentiated ES or iPS cell lines. There is a relatively unpredictable variation in hematopoietic differentiation between ES and iPS cell lines that could not be predicted based on phenotype or gene expression of the undifferentiated cells. These results demonstrate the influence of genetic background in variation of hematopoietic potential rather than the reprogramming process.

  15. An On-line Variational Bayesian Model for Multi-Person Tracking from Cluttered Scenes

    OpenAIRE

    Ba, Sileye; Alameda-Pineda, Xavier; Xompero, Alessio; Horaud, Radu

    2016-01-01

    Object tracking is an ubiquitous problem that appears in many applications such as remote sensing, audio processing, computer vision, human-machine interfaces, human-robot interaction, etc. Although thoroughly investigated in computer vision, tracking a time-varying number of persons remains a challenging open problem. In this paper, we propose an on-line variational Bayesian model for multi-person tracking from cluttered visual observations provided by person detectors. The contributions of ...

  16. The effect of lignite quality variation on the efficiency of on-line ash analyzers

    Energy Technology Data Exchange (ETDEWEB)

    Galetakis, Michael J. [Technical University of Crete, Dept. of Mineral Resources Engineering, University Campus, 73 100 Hania (Greece); Pavloudakis, Francis F. [Public Power Corporation SA, General Division of Mines, Kifisou and Dyrrahiou 89, 104 43 Athens (Greece)

    2009-12-01

    A sustainable coal industry needs to achieve a number of objectives including improvements in utilization of deposits, energy efficiency, and environmental performance during combustion. The ''Clean Coal Concept'' promises to combine the secure and low cost electricity supply offered by hard coal and lignite with adequate environmental precautions. In this context, modern quality control systems, which are greatly based on the on-line analyzers, play an important role in achieving sustainability targets. This paper examines the possibility of using commercial on-line analysis systems for monitoring the mineral matter content of low quality lignite mined from the lignite basin of Megalopolis, Peloponnese, Greece. The effect of the accuracy of the on-line analyzers to process control, when used for the characterization of low rank coals with complex and variable composition, is investigated by carrying out numerous bench- and pilot-scale trials. Pilot-scale trials were based on a dual energy gamma-ray transmission analyzer, which was installed on the conveyor belt that transports lignite from the mine pit to the homogenization stockyard. All measurement data were compared to data gathered during the realisation of similar trials in the lignite mines of Ptolemais Basin, Northern Greece. Results indicated that the accuracy of the on-line measurements was not satisfactory and did not allow lignite quality monitoring in real time. The achieved inferior accuracy of the on-line measurement's accuracy, compared to previous applications at other mining sites, was related to the intense variation of the mineral matter content of lignite and lignite composition, which distorted the calibration of the analyzer. The latter is based on certain assumptions regarding the average mass absorption coefficient of the organic and mineral matter contained in the lignite. Further experimental work is needed to investigate solutions for successful implementation of

  17. Ultraviolet and Optical Line Profile Variations in the Spectrum of {epsilon} Persei

    Energy Technology Data Exchange (ETDEWEB)

    Gies, D. R.; Kambe, E.; Josephs, T. S.; Bagnuolo, W. G. Jr.; Choi, Y. J.; Gudehus, D.; Guyton, K. M.; Hartkopf, W. I.; Hildebrand, J. L.; Kaye, A. B. (and others)

    1999-11-01

    The rapid variable star, {epsilon} Per (B0.5 IV-III), displays the largest amplitude profile fluctuations known among the growing number of massive, spectrum-variable stars. Here we present an analysis of a continuous 5 day run of IUE UV spectroscopy, and we show for the first time that the systematic, blue-to-red moving patterns observed in high-quality optical spectra are also present in the UV photospheric lines. We present cross-correlation functions of the individual spectra with that of a narrow-lined standard that produce a high signal-to-noise ratio representation of the blue-to-red moving bump patterns found in individual lines. We then use time series analysis methods to determine the periodic components of the profile variations (after reregistering the spectra to correct for binary motion). There are at least six periods present (ranging from 8.46 to 2.27 hr), and most of these signals are also found in optical line variations observed in 1986 (although the relative amplitudes have changed significantly). Furthermore, analysis of a shorter time series of IUE spectra from 1984 shows that similar periods were present then. We also present H{alpha} and He i {lambda}6678 profiles obtained with the Georgia State University Multi-Telescope Telescope, which were made simultaneously with IUE, and we show that the profile variations are essentially identical in the UV and optical ranges. We rule out rotational modulation and circumstellar gas obscuration as possible causes, and we suggest instead that the variations are the result of photospheric nonradial pulsations of relatively low degree (l=3-5). There were significant changes ({approx}10%) in the equivalent widths of the UV stellar wind lines during the IUE run, and we suggest that wind strengthening events are related to episodes of large-amplitude, constructive interference between the NRP modes. Thus, intermode beating may play an important role in promoting wind loss from massive stars. (c) (c) 1999

  18. Functional Coding Variation in Recombinant Inbred Mouse Lines Reveals Novel Serotonin Transporter-Associated Phenotypes

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Ana [Vanderbilt University; Airey, David [University of Tennessee Health Science Center, Memphis; Thompson, Brent [Vanderbilt University; Zhu, C [Vanderbilt University; Rinchik, Eugene M [ORNL; Lu, Lu [University of Tennessee Health Science Center, Memphis; Chesler, Elissa J [ORNL; Erikson, Keith [University of North Carolina; Blakely, Randy [Vanderbilt University

    2009-01-01

    The human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT, SLC6A4) figures prominently in the etiology or treatment of many prevalent neurobehavioral disorders including anxiety, alcoholism, depression, autism and obsessive-compulsive disorder (OCD). Here we utilize naturally occurring polymorphisms in recombinant inbred (RI) lines to identify novel phenotypes associated with altered SERT function. The widely used mouse strain C57BL/6J, harbors a SERT haplotype defined by two nonsynonymous coding variants (Gly39 and Lys152 (GK)). At these positions, many other mouse lines, including DBA/2J, encode Glu39 and Arg152 (ER haplotype), assignments found also in hSERT. Synaptosomal 5-HT transport studies revealed reduced uptake associated with the GK variant. Heterologous expression studies confirmed a reduced SERT turnover rate for the GK variant. Experimental and in silico approaches using RI lines (C57Bl/6J X DBA/2J=BXD) identifies multiple anatomical, biochemical and behavioral phenotypes specifically impacted by GK/ER variation. Among our findings are multiple traits associated with anxiety and alcohol consumption, as well as of the control of dopamine (DA) signaling. Further bioinformatic analysis of BXD phenotypes, combined with biochemical evaluation of SERT knockout mice, nominates SERT-dependent 5-HT signaling as a major determinant of midbrain iron homeostasis that, in turn, dictates ironregulated DA phenotypes. Our studies provide a novel example of the power of coordinated in vitro, in vivo and in silico approaches using murine RI lines to elucidate and quantify the system-level impact of gene variation.

  19. Efficient selection of a high-yield line by using somaclonal variation in Japanese butterbur (Petasites japonicus)

    National Research Council Canada - National Science Library

    Iwamoto, Yuzuri; Nakasone, Wataru; Ezura, Hiroshi

    2007-01-01

    To induce somaclonal variations related to plant yield, adventitious buds were directly regenerated from immature flowerheads of a selected line A of the 'Aichi Wase Fuki' of Japanese butterbur (Petasites japonicus...

  20. Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population.

    Science.gov (United States)

    Simbiri, Kenneth O; Smith, Nicholas A; Otieno, Richard; Wohlford, Eric E M; Daud, Ibrahim I; Odada, Sumba P; Middleton, Frank; Rochford, Rosemary

    2015-01-01

    Epstein-Barr virus (EBV) is associated with Burkitt's lymphoma (BL), and in regions of sub-Saharan Africa where endemic BL is common, both the EBV Type 1 (EBV-1) and EBV Type 2 strains (EBV-2) are found. Little is known about genetic variation of EBV strains in areas of sub-Saharan Africa. In the present study, spontaneous lymphoblastoid cell lines (LCLs) were generated from samples obtained from Kenya. Polymerase chain reaction (PCR) amplification of the EBV genome was done using multiple primers and sequenced by next-generation sequencing (NGS). Phylogenetic analyses against the published EBV-1 and EBV-2 strains indicated that one sample, LCL10 was closely related to EBV-2, while the remaining 3 LCL samples were more closely related to EBV-1. Moreover, single nucleotide polymorphism (SNP) analyses showed clustering of LCL variants. We further show by analysis of EBNA-1, BLLF1, BPLF1, and BRRF2 that latent genes are less conserved than lytic genes in these LCLs from a single geographic region. In this study we have shown that NGS is highly useful for deciphering detailed inter and intra-variations in EBV genomes and that within a geographic region different EBV genetic variations can co-exist, the implications of which warrant further investigation. The findings will enhance our understanding of potential pathogenic variants critical to the development and maintenance of EBV-associated malignancies.

  1. Characterization of the Polish Primitive Horse (Konik) maternal lines using mitochondrial D-loop sequence variation.

    Science.gov (United States)

    Cieslak, Jakub; Wodas, Lukasz; Borowska, Alicja; Cothran, Ernest G; Khanshour, Anas M; Mackowski, Mariusz

    2017-01-01

    The Polish Primitive Horse (PPH, Konik) is a Polish native horse breed managed through a conservation program mainly due to its characteristic phenotype of a primitive horse. One of the most important goals of PPH breeding strategy is the preservation and equal development of all existing maternal lines. However, until now there was no investigation into the real genetic diversity of 16 recognized PPH dam lines using mtDNA sequence variation. Herein, we describe the phylogenetic relationships between the PPH maternal lines based upon partial mtDNA D-loop sequencing of 173 individuals. Altogether, 19 mtDNA haplotypes were detected in the PPH population. Five haplotypes were putatively novel while the remaining 14 showed the 100% homology with sequences deposited in the GenBank database, represented by both modern and primitive horse breeds. Generally, comparisons found the haplotypes conformed to 10 different recognized mtDNA haplogroups (A, B, E, G, J, M, N, P, Q and R). A multi-breed analysis has indicated the phylogenetic similarity of PPH and other indigenous horse breeds derived from various geographical regions (e.g., Iberian Peninsula, Eastern Europe and Siberia) which may support the hypothesis that within the PPH breed numerous ancestral haplotypes (found all over the world) are still present. Only in the case of five maternal lines (Bona, Dzina I, Geneza, Popielica and Zaza) was the segregation of one specific mtDNA haplotype observed. The 11 remaining lines showed a higher degree of mtDNA haplotype variability (2-5 haplotypes segregating in each line). This study has revealed relatively high maternal genetic diversity in the small, indigenous PPH breed (19 haplotypes, overall HapD = 0.92). However, only some traditionally distinguished maternal lines can be treated as genetically pure. The rest show evidence of numerous mistakes recorded in the official PPH pedigrees. This study has proved the importance of maternal genetic diversity monitoring based upon

  2. Characterization of the Polish Primitive Horse (Konik maternal lines using mitochondrial D-loop sequence variation

    Directory of Open Access Journals (Sweden)

    Jakub Cieslak

    2017-08-01

    Full Text Available The Polish Primitive Horse (PPH, Konik is a Polish native horse breed managed through a conservation program mainly due to its characteristic phenotype of a primitive horse. One of the most important goals of PPH breeding strategy is the preservation and equal development of all existing maternal lines. However, until now there was no investigation into the real genetic diversity of 16 recognized PPH dam lines using mtDNA sequence variation. Herein, we describe the phylogenetic relationships between the PPH maternal lines based upon partial mtDNA D-loop sequencing of 173 individuals. Altogether, 19 mtDNA haplotypes were detected in the PPH population. Five haplotypes were putatively novel while the remaining 14 showed the 100% homology with sequences deposited in the GenBank database, represented by both modern and primitive horse breeds. Generally, comparisons found the haplotypes conformed to 10 different recognized mtDNA haplogroups (A, B, E, G, J, M, N, P, Q and R. A multi-breed analysis has indicated the phylogenetic similarity of PPH and other indigenous horse breeds derived from various geographical regions (e.g., Iberian Peninsula, Eastern Europe and Siberia which may support the hypothesis that within the PPH breed numerous ancestral haplotypes (found all over the world are still present. Only in the case of five maternal lines (Bona, Dzina I, Geneza, Popielica and Zaza was the segregation of one specific mtDNA haplotype observed. The 11 remaining lines showed a higher degree of mtDNA haplotype variability (2–5 haplotypes segregating in each line. This study has revealed relatively high maternal genetic diversity in the small, indigenous PPH breed (19 haplotypes, overall HapD = 0.92. However, only some traditionally distinguished maternal lines can be treated as genetically pure. The rest show evidence of numerous mistakes recorded in the official PPH pedigrees. This study has proved the importance of maternal genetic diversity

  3. Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity.

    Science.gov (United States)

    Nishizawa, Masatoshi; Chonabayashi, Kazuhisa; Nomura, Masaki; Tanaka, Azusa; Nakamura, Masahiro; Inagaki, Azusa; Nishikawa, Misato; Takei, Ikue; Oishi, Akiko; Tanabe, Koji; Ohnuki, Mari; Yokota, Hidaka; Koyanagi-Aoi, Michiyo; Okita, Keisuke; Watanabe, Akira; Takaori-Kondo, Akifumi; Yamanaka, Shinya; Yoshida, Yoshinori

    2016-09-01

    Variation in the differentiation capacity of induced pluripotent stem cells (iPSCs) to specific lineages is a significant concern for their use in clinical applications and disease modeling. To identify factors that affect differentiation capacity, we performed integration analyses between hematopoietic differentiation performance and molecular signatures such as gene expression, DNA methylation, and chromatin status, using 35 human iPSC lines and four ESC lines. Our analyses revealed that hematopoietic commitment of PSCs to hematopoietic precursors correlates with IGF2 expression level, which in turn depends on signaling-dependent chromatin accessibility at mesendodermal genes. Maturation capacity for conversion of PSC-derived hematopoietic precursors to mature blood associates with the amount and pattern of DNA methylation acquired during reprogramming. Our study therefore provides insight into the molecular features that determine the differential capacities seen among human iPSC lines and, through the predictive potential of this information, highlights a way to select optimal iPSCs for clinical applications. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Weld line optimization on thermoplastic elastomer micro injection moulded components using 3D focus variation optical microscopy

    DEFF Research Database (Denmark)

    Hasnaes, F.B.; Elsborg, R.; Tosello, G.

    2015-01-01

    The presented study investigates weld line depth development across a micro suspension ring. A focus variation microscope was used to obtain 3D images of the weld line area. Suspension rings produced with different micro injection moulding process parameters were examined to identify the correlat...

  5. Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola

    NARCIS (Netherlands)

    Stergiopoulos, I.; Nistelrooy, van J.G.M.; Kema, G.H.J.; Waard, de M.A.

    2003-01-01

    Molecular mechanisms that account for variation in base-line sensitivity to azole fungicides were examined in a collection of twenty field isolates, collected in France and Germany, of the wheat pathogen Mycosphaerella graminicola (Fuckel) Schroeter. The isolates tested represent the wide base-line

  6. On the discovery of K I 7699 Å line strength variation during the 1982-1984 eclipse of ε Aurigae

    Science.gov (United States)

    Parthasarathy, M.

    2017-02-01

    The discovery of K I 7699 Å line strength variations during the 1982-1984 eclipse of ε Aurigae is described. The equivalent widths and radial velocities of the K I 7699 Å line derived from spectra obtained during 1981 November-1983 July with the 2.1 m Otto Struve reflector telescope of the McDonald observatory are presented.

  7. Discovery of Time Variation of the Intensity of Molecular Lines in IRC+10216 in The Submillimeter and Far Infrared Domains.

    Science.gov (United States)

    Cernicharo, J; Teyssier, D; Quintana-Lacaci, G; Daniel, F; Agúndez, M; Prieto, L Velilla; Decin, L; Guélin, M; Encrenaz, P; García-Lario, P; de Beck, E; Barlow, M J; Groenewegen, M A T; Neufeld, D; Pearson, J

    2014-10-20

    We report on the discovery of strong intensity variations in the high rotational lines of abundant molecular species towards the archetypical circumstellar envelope of IRC+10216. The observations have been carried out with the HIFI instrument on board Herschel and with the IRAM 30-m telescope. They cover several observing periods spreading over 3 years. The line intensity variations for molecules produced in the external layers of the envelope most probably result from time variations in the infrared pumping rates. We analyze the main implications this discovery has on the interpretation of molecular line emission in the envelopes of Mira-type stars. Radiative transfer calculations have to take into account both the time variability of infrared pumping and the possible variation of the dust and gas temperatures with stellar phase in order to reproduce the observation of molecular lines at different epochs. The effect of gas temperature variations with stellar phase could be particularly important for lines produced in the innermost regions of the envelope. Each layer of the circumstellar envelope sees the stellar light radiation with a different lag time (phase). Our results show that this effect must be included in the models. The sub-mm and FIR lines of AGB stars cannot anymore be considered as safe intensity calibrators.

  8. Evaluation of Genetic Variation of the Breeding Lines Isolated from Sesame (Sesamum indicum L. landraces

    Directory of Open Access Journals (Sweden)

    F Nasiri

    2013-04-01

    Full Text Available This study was carried out to evaluate the genetic diversity of the breeding lines isolated from the sesame landraces. Seventy genotypes were evaluated in randomized complete block design with two replications in 2008. The results showed that there were significant differences among the genotypes for all of the studied traits such as days to maturity, plant height and seed yield. There was no difference between the phenotypic and genetic coefficients of variations for most of the traits, thus it was concluded that the majority of their observed variations was due to the genetic factors. The grain yield of the genotypes ranged from 1089 to 4650 kg/ha. One of the breeding line isolated from Birjand landrace had the highest mean of days to maturity (170 days and Yekta genotype had the lowest mean for this trait (118 days. The range of plant height among genotypes was 123 to 179 cm and the mean of capsule per plant was ranged from 46 to 181. Branches per plant had the highest broad-sense heritability (81.1 % and the estimated broad-sense heritability for grain yield was 75.5%. Cluster analysis classified the genotypes in three distinct groups and there were significant differences among these groups for all of the traits, except days to maturity. Genotypes classified in the second group had the most capsule per plant and grain yield and they can be used for genetic improvement of this trait. Meanwhile genotypes of the first group can be used for genetic improvement of plant height and branches per plant.

  9. Variational method for the nonlinear dynamics of an elliptic magnetic stagnation line

    Energy Technology Data Exchange (ETDEWEB)

    Khater, A.H.; Seadawy, A.R. [Beni-Suef Univ., Mathematics Dept., Faculty of Science (Egypt); Khater, A.H.; Callebaut, D.K. [Antwerp Univ., Dept. Natuurkunde (Belgium); Helal, M.A. [Cairo Univ., Mathematics Dept., Faculty of Science, Giza (Egypt)

    2006-08-15

    The nonlinear evolution of the kink instability of a plasma with an elliptic magnetic stagnation line is studied by means of an amplitude expansion of the ideal magnetohydrodynamic equations. Wahlberg et al. have shown that, near marginal stability, the nonlinear evolution of the stability can be described in terms of a two-dimensional potential U(X,Y), where X and Y represent the amplitudes of the perturbations with positive and negative helical polarization. The potential U(X,Y) is found to be nonlinearly stabilizing for all values of the polarization. In our paper a Lagrangian and an invariant variational principle for two coupled nonlinear ordinal differential equations describing the nonlinear evolution of the stagnation line instability with arbitrary polarization are given. Using a trial function in a rectangular box we find the functional integral. The general case for the two box potential can be obtained on the basis of a different Ansatz where we approximate the Jost function by polynomials of order n instead of a piecewise linear function. An example for the second order is given to illustrate the general case. Some considerations concerning solar filaments and filament bands (circular or straight) are indicated as possible applications besides laboratory experiments with cusp geometry corresponding to quadrupolar cusp geometries for some clouds and thunderstorms. (authors)

  10. Biochemical and genetic variation in Mycoplasma fermentans strains from cell line, human and animal sources.

    Science.gov (United States)

    Afshar, B; Nicholas, R A J; Pitcher, D; Fielder, M D; Miles, R J

    2009-08-01

    To investigate the inter-strain variation in (i) substrate utilization and (ii) the restriction fragment length polymorphism (RFLP) pattern based on the distribution of an insertion element (IS1550) in Mycoplasma fermentans strains, and to establish any correlation between subgroups within the species and their source or habitat. Using a sensitive dynamic pH method, the pattern and kinetics of substrate utilization by a panel of 17 M. fermentans strains from various sources was determined. This study correlated the biochemical characteristics of these strains with RFLP patterns based on the distribution of an insertion sequence (IS1550) with the sources of the strains. The test isolates were divided into four major groups according to the pattern of substrates metabolized. Interestingly, two strains isolated from cell lines in RFLP cluster I failed to utilize arginine. Ovine strains showed distinct substrate utilization patterns and produced RFLP patterns not previously encountered. All strains utilized glucose, but the ability to utilize arginine, fructose and N-acetyl glucosamine varied. There was also some correlation evident between the metabolic data and the RFLP clusters. This study has provided a better understanding of the biochemical and genetic diversity of M. fermentans strains from various sources.

  11. Blumensaat's line is not always straight: morphological variations of the lateral wall of the femoral intercondylar notch.

    Science.gov (United States)

    Iriuchishima, Takanori; Ryu, Keinosuke; Aizawa, Shin; Fu, Freddie H

    2016-09-01

    The purpose of this study was to evaluate the morphological variations of the lateral wall of the femoral intercondylar notch. Fifty-two non-paired human cadaver knees were used. All soft tissues around the knee were resected except the ACL. The ACL was cut in the middle, and the femoral bone was cut at the most proximal point of the femoral notch parallel to the plane of the femoral bone shaft. The ACL was carefully dissected, and the periphery of the ACL insertion site was outlined on the femoral side. An accurate lateral view of the femoral condyle was photographed with a digital camera, and the images were downloaded to a personal computer. The morphological variations of Blumensaat's line, the height and area of the lateral wall of the femoral intercondylar notch and the size of the femoral ACL footprints were measured with Image J software. Blumensaat's line exhibited three types of morphological variations. A straight line was observed in 19 knees (37 %) (straight type). A protrusion spanning less than half of the line was observed at the proximal part of Blumensaat's line in 10 knees (19 %) (small hill type). A protrusion spanning more than half of the line was observed at the proximal part of the line in 23 knees (44 %) (large hill type). In some knees with this large hill type variation, the appearance was similar to that of anterior spur. No significant differences between these three types were observed in either the height and area of the lateral wall of the femoral intercondylar notch or the area of the femoral ACL footprint. In conclusion, Blumensaat's line has three types of morphological variations (straight, small hill and large hill types). For the clinical relevance, when ACL surgery is performed in knees with small or large hill type variations, surgeons should pay close attention to femoral tunnel evaluation and placement, especially for the use of Quadrant method. The grid placement of Quadrant method would be changed in the knees of these

  12. Gene expression profiles deciphering leaf senescence variation between early- and late-senescence cotton lines.

    Directory of Open Access Journals (Sweden)

    Xiangqiang Kong

    Full Text Available Leaf senescence varies greatly among genotypes of cotton (Gossypium hirsutium L, possibly due to the different expression of senescence-related genes. To determine genes involved in leaf senescence, we performed genome-wide transcriptional profiling of the main-stem leaves of an early- (K1 and a late-senescence (K2 cotton line at 110 day after planting (DAP using the Solexa technology. The profiling analysis indicated that 1132 genes were up-regulated and 455 genes down-regulated in K1 compared with K2 at 110 DAP. The Solexa data were highly consistent with, and thus were validated by those from real-time quantitative PCR (RT-PCR. Most of the genes related to photosynthesis, anabolism of carbohydrates and other biomolecules were down-regulated, but those for catabolism of proteins, nucleic acids, lipids and nutrient recycling were mostly up-regulated in K1 compared with K2. Fifty-one differently expressed hormone-related genes were identified, of which 5 ethylene, 3 brassinosteroid (BR, 5 JA, 18 auxin, 8 GA and 1 ABA related genes were up-regulated in K1 compared with K2, indicating that these hormone-related genes might play crucial roles in early senescence of K1 leaves. Many differently expressed transcription factor (TF genes were identified and 11 NAC and 8 WRKY TF genes were up-regulated in K1 compared with K2, suggesting that TF genes, especially NAC and WRKY genes were involved in early senescence of K1 leaves. Genotypic variation in leaf senescence was attributed to differently expressed genes, particularly hormone-related and TF genes.

  13. Time Variations of Observed Hα Line Profiles and Precipitation Depths of Nonthermal Electrons in a Solar Flare

    Science.gov (United States)

    Falewicz, Robert; Radziszewski, Krzysztof; Rudawy, Paweł; Berlicki, Arkadiusz

    2017-10-01

    We compare time variations of the Hα and X-ray emissions observed during the pre-impulsive and impulsive phases of the C1.1-class solar flare on 2013 June 21 with those of plasma parameters and synthesized X-ray emission from a 1D hydrodynamic numerical model of the flare. The numerical model was calculated assuming that the external energy is delivered to the flaring loop by nonthermal electrons (NTEs). The Hα spectra and images were obtained using the Multi-channel Subtractive Double Pass spectrograph with a time resolution of 50 ms. The X-ray fluxes and spectra were recorded by RHESSI. Pre-flare geometric and thermodynamic parameters of the model and the delivered energy were estimated using RHESSI data. The time variations of the X-ray light curves in various energy bands and those of the Hα intensities and line profiles were well correlated. The timescales of the observed variations agree with the calculated variations of the plasma parameters in the flaring loop footpoints, reflecting the time variations of the vertical extent of the energy deposition layer. Our result shows that the fast time variations of the Hα emission of the flaring kernels can be explained by momentary changes of the deposited energy flux and the variations of the penetration depths of the NTEs.

  14. ArF-resist line width slimming variation with threshold level in high precision CD-SEM measurement

    Science.gov (United States)

    Kawada, Hiroki; Ojima, Yuki

    2005-05-01

    Line width slimming (LWS) occurring in ArF photo-resist is measured with various threshold levels. The LWS decreases as the threshold level decrease, with electron"s landing voltage (Ve) = 800 V. Contrary to this, with Ve = 300 V the LWS slightly increases as the threshold level decrease. The line edge detected by threshold = 20% locates in the sidewall where the elevation angle is nearly zero, whilst the line edge by threshold = 80% locates in the top corner where the elevation angle is more than 30 degrees. To estimate the electron dose that is sensitive to the elevation angle of the incident electron, we used an in-house made Monte Carlo simulator. The LWS variation with the threshold level can be explained by calculated electron dose ratio that is sensitive to the elevation angle.

  15. Genetic variation between Spanish and American versions of sweet corn inbred lines

    OpenAIRE

    Revilla Temiño, Pedro; Abuín, María del Carmen; Malvar Pintos, Rosa Ana; Soengas Fernández, María del Pilar; Ordás López, Bernardo; Ordás Pérez, Amando

    2005-01-01

    Conservation of maize inbred lines in different stations causes variability among strains. The objective of this research was to determine agronomic and molecular differences in American sweet corn inbreds maintained in Spain. American and Spanish strains of five sweet corn inbred lines were characterized by using 34 RAPD primers that produced 168 consistent bands. Strains of four of these inbreds were crossed in a diallel design, and hybrids were evaluated in four environments in northwester...

  16. [Cytogenetic variation of Ungernia victoris cell lines during cultivation on culture media of different composition].

    Science.gov (United States)

    Bublik, E N; Adonin, V I; Kunakh, V A

    2008-01-01

    Chromosome numbers of U. victoris cell lines obtained from the same bulb and cultured for a long time on different agar-solidified and liquid nutrient media differed significantly. The components of the nutrient media including phytohormones did not influence the ratio of cells with different ploidy levels in various lines while transfer of the calluses to the liquid media resulted in the increase of diploid metaphase frequencies.

  17. LINES

    Directory of Open Access Journals (Sweden)

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  18. NLTE opacity calculations: C-Si and C-Ge mixtures

    Science.gov (United States)

    Jarrah, W.; Benredjem, D.; Pain, J.-C.; Dubau, J.

    2017-09-01

    The opacity is an important issue in the knowledge of the radiative properties of ICF and astrophysical plasmas. We present the opacity of dopants (silicon, germanium) embedded in the ablator of some ICF capsules. In recent works, Hill and Rose calculated the opacity of silicon in LTE and non-LTE plasmas, while Minguez and co-workers focused on the opacity of carbon. We have used the Cowan code to calculate the atomic structure of carbon, silicon and germanium in various ionic stages. The cross-sections of atomic processes (collisional excitation, collisional ionization) are obtained by fitting the values given by the code FAC to the Van Regemorter-like formulas of Sampson and Zhang. A corrected Gaunt factor is then obtained. A collisional-radiative code was developed in order to obtain the ionic populations, the level populations and the opacity. Line broadening and line shift are taken into account. The ionization potential depression is included in our calculations. The effect of a radiation field on the opacity is examined.

  19. Finite line-source model for borehole heat exchangers. Effect of vertical temperature variations

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Tatyana V.; Fernandez, Esther; Santander, Juan Luis G.; Isidro, Jose Maria; Perez, Jezabel; Cordoba, Pedro J. Fernandez de [Instituto Universitario de Matematica Pura y Aplicada, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain); Montero, Alvaro; Urchueguia, Javier F. [Instituto de Ingenieria Energetica, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain)

    2009-06-15

    A solution to the three-dimensional finite line-source (FLS) model for borehole heat exchangers (BHEs) that takes into account the prevailing geothermal gradient and allows arbitrary ground surface temperature changes is presented. Analytical expressions for the average ground temperature are derived by integrating the exact solution over the line-source depth. A self-consistent procedure to evaluate the in situ thermal response test (TRT) data is outlined. The effective thermal conductivity and the effective borehole thermal resistance can be determined by fitting the TRT data to the time-series expansion obtained for the average temperature. (author)

  20. Genetic variation assessed with microsatellites in mass selection lines of the Pacific oyster ( Crassostrea gigas) in China

    Science.gov (United States)

    Wang, Xubo; Li, Qi; Yu, Hong; Kong, Lingfeng

    2016-12-01

    Four successive mass selection lines of the Pacific oyster, Crassostrea gigas, selected for faster growth in breeding programs in China were examined at ten polymorphic microsatellite loci to assess the level of allelic diversity and estimate the effective population size. These data were compared with those of their base population. The results showed that the genetic variation of the four generations were maintained at high levels with an average allelic richness of 18.8-20.6, and a mean expected heterozygosity of 0.902-0.921. They were not reduced compared with those of their base population. Estimated effective population sizes based on temporal variances in microsatellite frequencies were smaller to that of sex ratio-corrected broodstock count estimates. Using a relatively large number of broodstock and keeping an equal sex ratio in the broodstock each generation may have contributed to retaining the original genetic diversity and maintaining relatively large effective population size. The results obtained in this study showed that the genetic variation was not affected greatly by mass selection progress and high genetic variation still existed in the mass selection lines, suggesting that there is still potential for increasing the gains in future generations of C. gigas. The present study provided important information for future genetic improvement by selective breeding, and for the design of suitable management guidelines for genetic breeding of C. gigas.

  1. Comparison of various NLTE codes in computing the charge-state populations of an argon plasma

    Energy Technology Data Exchange (ETDEWEB)

    Stone, S.R.; Weisheit, J.C.

    1984-11-01

    A comparison among nine computer codes shows surprisingly large differences where it had been believed that the theroy was well understood. Each code treats an argon plasma, optically thin and with no external photon flux; temperatures vary around 1 keV and ion densities vary from 6 x 10/sup 17/ cm/sup -3/ to 6 x 10/sup 21/ cm/sup -3/. At these conditions most ions have three or fewer bound electrons. The calculated populations of 0-, 1-, 2-, and 3-electron ions differ from code to code by typical factors of 2, in some cases by factors greater than 300. These differences depend as sensitively on how may Rydberg states a code allows as they do on variations among computed collision rates. 29 refs., 23 figs.

  2. Analysis of natural allelic variation in Arabidopsis using a multiparent recombinant inbred line population

    NARCIS (Netherlands)

    Huang, X.; Caldas Paulo, M.J.; Boer, M.P.; Effgen, S.; Keizer, P.; Koornneef, M.; Eeuwijk, van F.A.

    2011-01-01

    To exploit the diversity in Arabidopsis thaliana, eight founder accessions were crossed to produce six recombinant inbred line (RIL) subpopulations, together called an Arabidopsis multiparent RIL (AMPRIL) population. Founders were crossed pairwise to produce four F1 hybrids. These F1s were crossed

  3. Herschel Extreme Lensing Line Observations: [CII] Variations in Galaxies at Redshifts z=1-3

    Science.gov (United States)

    Malhotra, Sangeeta; Rhoads, James E.; Finkelstein, K.; Yang, Huan; Carilli, Chris; Combes, Françoise; Dassas, Karine; Finkelstein, Steven; Frye, Brenda; Gerin, Maryvonne; Guillard, Pierre; Nesvadba, Nicole; Rigby, Jane; Shin, Min-Su; Spaans, Marco; Strauss, Michael A.; Papovich, Casey

    2017-01-01

    We observed the [C ii] line in 15 lensed galaxies at redshifts 1 HELLO sample is similar to the values seen for low-redshift galaxies, indicating that small grains and PAHs dominate the heating in the neutral ISM, although some of the high [CII]/FIR ratios may be due to turbulent heating. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.

  4. Strategic variation in mobbing as a front line of defense against brood parasitism.

    Science.gov (United States)

    Welbergen, Justin A; Davies, Nicholas B

    2009-02-10

    Coevolutionary arms races, where adaptations in one party select for counter-adaptations in another and vice versa, are fundamental to interactions between organisms and their predators, pathogens, and parasites [1]. Avian brood parasites and their hosts have emerged as model systems for studying such reciprocal coevolutionary processes [2, 3]. For example, hosts have evolved changes in egg appearance and rejection of foreign eggs in response to brood parasitism from cuckoos, and cuckoos have evolved host-egg mimicry as a counter-response [4-6]. However, the host's front line of defense is protecting the nest from being parasitized in the first place [7-10], yet little is known about the effectiveness of nest defense as an antiparasite adaptation, and its coevolutionary significance remains poorly understood [10]. Here we show first that mobbing of common cuckoos Cuculus canorus by reed warblers Acrocephalus scirpaceus is an effective defense against parasitism. Second, mobbing of cuckoos is a phenotypically plastic trait that is modified strategically according to local parasitism risk. This supports the view that hosts use a "defense in-depth strategy," with successive flexible lines of defense that coevolve with corresponding offensive lines of the parasite. This highlights the need for more holistic research into the coevolutionary consequences when multiple adaptations and counter-adaptations evolve in concert [11].

  5. Observations of Fe XIV Line Intensity Variations in the Solar Corona During the 21 August 2017 Solar Eclipse

    Science.gov (United States)

    Johnson, Payton; Ladd, Edwin

    2018-01-01

    We present time- and spatially-resolved observations of the inner solar corona in the 5303 Å line of Fe XIV, taken during the 21 August 2017 solar eclipse from a field observing site in Crossville, TN. These observations are used to characterize the intensity variations in this coronal emission line, and to compare with oscillation predictions from models for heating the corona by magnetic wave dissipation.The observations were taken with two Explore Scientific ED 102CF 102 mm aperture triplet apochromatic refractors. One system used a DayStar custom-built 5 Å FWHM filter centered on the Fe XIV coronal spectral line and an Atik Titan camera for image collection. The setup produced images with a pixel size of 2.15 arcseconds (~1.5 Mm at the distance to the Sun), and a field of view of 1420 x 1060 arcseconds, covering approximately 20% of the entire solar limb centered near the emerging sunspot complex AR 2672. We obtained images with an exposure time of 0.22 seconds and a frame rate of 2.36 Hz, for a total of 361 images during totality.An identical, co-aligned telescope/camera system observed the same portion of the solar corona, but with a 100 Å FWHM Baader Planetarium solar continuum filter centered on a wavelength of 5400 Å. Images with an exposure time of 0.01 seconds were obtained with a frame rate of 4.05 Hz. These simultaneous observations are used as a control to monitor brightness variations not related to coronal line oscillations.

  6. Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content.

    Science.gov (United States)

    Zhang, Hui; Du, Zhi-Qiang; Dong, Jia-Qiang; Wang, Hai-Xia; Shi, Hong-Yan; Wang, Ning; Wang, Shou-Zhi; Li, Hui

    2014-06-24

    The chicken (Gallus gallus) is an important model organism that bridges the evolutionary gap between mammals and other vertebrates. Copy number variations (CNVs) are a form of genomic structural variation widely distributed in the genome. CNV analysis has recently gained greater attention and momentum, as the identification of CNVs can contribute to a better understanding of traits important to both humans and other animals. To detect chicken CNVs, we genotyped 475 animals derived from two broiler chicken lines divergently selected for abdominal fat content using chicken 60 K SNP array, which is a high-throughput method widely used in chicken genomics studies. Using PennCNV algorithm, we detected 438 and 291 CNVs in the lean and fat lines, respectively, corresponding to 271 and 188 CNV regions (CNVRs), which were obtained by merging overlapping CNVs. Out of these CNVRs, 99% were confirmed also by the CNVPartition program. These CNVRs covered 40.26 and 30.60 Mb of the chicken genome in the lean and fat lines, respectively. Moreover, CNVRs included 176 loss, 68 gain and 27 both (i.e. loss and gain within the same region) events in the lean line, and 143 loss, 25 gain and 20 both events in the fat line. Ten CNVRs were chosen for the validation experiment using qPCR method, and all of them were confirmed in at least one qPCR assay. We found a total of 886 genes located within these CNVRs, and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses showed they could play various roles in a number of biological processes. Integrating the results of CNVRs, known quantitative trait loci (QTL) and selective sweeps for abdominal fat content suggested that some genes (including SLC9A3, GNAL, SPOCK3, ANXA10, HELIOS, MYLK, CCDC14, SPAG9, SOX5, VSNL1, SMC6, GEN1, MSGN1 and ZPAX) may be important for abdominal fat deposition in the chicken. Our study provided a genome-wide CNVR map of the chicken genome, thereby contributing to our understanding of

  7. The temporal variation of the frequency of high latitude field line resonances

    Energy Technology Data Exchange (ETDEWEB)

    Waters, C.L.; Samson, J.C.; Donovan, E.F. [Univ. of Alberta, Edmonton (Canada)

    1995-05-01

    The authors report observations of ULF continuum field line resonance spectra using the Canadian Auroral Network for the OPEN Program Unified Study (CANOPUS) array. They use cross spectral procedures to analyze the data from magnetometer arrays. Observations are typically seen to start near dawn at frequencies near 2 mHz, to increase over several hours to 5 - 10 mHz, and then to slowly decrease back to 2 mHz over the remainder of the day. The waves are thought to be part of a resonant Alfven continuum. Using magnetic field models and a cold plasma magnetohydrodynamics model, the authors infer plasma densities from the resonant frequencies.

  8. Variation of stemline karyotype in a HeLa cell line.

    Science.gov (United States)

    Ghosh, S; Ghosh, I

    1975-10-27

    100 karyotypes of a HeLa cell line (modal number 69) were studied in details. It was observed that the stemline cells of this "triploid" somatic cell population showed high degree of chromosomal polymorphism. It has been discussed that the stemline cells have number of extra chromosomes (or parts of chromosomes) which are not essential for the genetic integrity of this cell population. A loss of some of these chromosomes (or their parts) does not induce any appreciable change in the genetic make-up of these cells. The broken chromosomes lose their identity and are grouped together with the non-homologues, when the Denver system of classification is followed. However, it has been argued that in absence of any other acceptable system for classification, the Denver system can still be employed for analyzing human chromosomes both at diploid and abnormal heteroploid level. It has been held in contrast to the pseudo-stemline concept that these cells in general, have the essential genes in common and are responsible for the genetic make-up of this cell line and constitute together the stemline of this somatic cell population.

  9. Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival

    DEFF Research Database (Denmark)

    Song, H.; Hogdall, E.; Ramus, S.J.

    2008-01-01

    .05) in these genes. The genotypes of each polymorphism were tested for association with survival by Cox regression analysis. RESULTS: A nominally statistically significant association between genotype and ovarian cancer survival was observed for polymorphisms in CCND2 and CCNE1. The per-allele hazard ratios (95......PURPOSE: Somatic alterations have been shown to correlate with ovarian cancer prognosis and survival, but less is known about the effects on survival of common inherited genetic variation. Of particular interest are genes involved in cell cycle pathways, which regulate cell division and could......) and survival among women with invasive ovarian cancer participating in a multicenter case-control study from United Kingdom, Denmark, and United States. DNAs from up to 1,499 women were genotyped for 97 single-nucleotide polymorphisms that tagged the known common variants (minor allele frequency > or = 0...

  10. Permethrin resistance variation and susceptible reference line isolation in a field population of the mosquito, Culex quinquefasciatus (Diptera: Culicidae).

    Science.gov (United States)

    Yang, Ting; Liu, Nannan

    2014-10-01

    This study examines the genetic variations and mechanisms involved in the development of permethrin resistance in individual mosquitoes from a field population of Culex quinquefasciatus, HAmCq(G0) , and characterizes susceptible reference lines of mosquitoes with a similar genetic background to the field HAmCq(G0) strain. Six upregulated cytochrome P450 genes, CYP9M10, CYP9J34, CYP6P14, CYP9J40, CYP6AA7, and CYP4C52v1, previously identified as being upregulated in the larvae of resistant HAmCq(G8) mosquitoes were examined in the larvae of 3 strains (susceptible S-Lab, parental HAmCq(G0) and permethrin-selected highly resistant HAmCq(G8) ) and 8 HAmCq(G0) single-egg raft colonies, covering a range of levels of susceptibility/resistance to permethrin and exhibiting different variations in the expression of A and/or T alleles at the L-to-F kdr locus of the sodium channel. The 2 lines with the lowest tolerance to permethrin and bearing solely the susceptible A allele at the L-to-F kdr locus of the sodium channels, from colonies Cx_SERC5 and Cx_SERC8, showed lower or similar levels of all 6 of the P450 genes tested compared with the S-Lab strain, suggesting that these 2 lines could be used as the reference mosquitoes in future studies characterizing insecticide resistance in HAmCq mosquitoes. This study also provides a detailed investigation of the mechanisms involved in insecticide resistance in individuals within a population: individuals with elevated levels of resistance to permethrin all displayed one or more potential resistance mechanisms-either elevated levels of P450 gene expression, or L-to-F mutations in the sodium channel, or both. © 2013 Institute of Zoology, Chinese Academy of Sciences.

  11. Herschel Extreme Lensing Line Observations: [CII] Variations in Galaxies at Redshifts z=1-3*

    Science.gov (United States)

    Malhotra, Sangeeta; Rhoads, James E.; Finkelstein, K.; Yang, Huan; Carilli, Chris; Combes, Francoise; Dassas, Karine; Finkelstein, Steven; Frye, Brenda; Gerin, Maryvonne; hide

    2017-01-01

    We observed the [C II] line in 15 lensed galaxies at redshifts 1 less than z less than 3 using HIFI on the Herschel Space Observatory and detected 14/15 galaxies at 3sigma or better. High magnifications enable even modestly luminous galaxies to be detected in [C II] with Herschel. The [C II] luminosity in this sample ranges from 8 × 10(exp 7) solar luminosity to 3.7 × 10(exp 9) solar luminosity (after correcting for magnification), confirming that [C II] is a strong tracer of the ISM at high redshifts. The ratio of the [C II] line to the total far-infrared (FIR) luminosity serves as a measure of the ratio of gas to dust cooling and thus the efficiency of the grain photoelectric heating process. It varies between 3.3% and 0.09%. We compare the [C II]/FIR ratio to that of galaxies at z = 0 and at high redshifts and find that they follow similar trends. The [C II]/FIR ratio is lower for galaxies with higher dust temperatures. This is best explained if increased UV intensity leads to higher FIR luminosity and dust temperatures, but gas heating does not rise due to lower photoelectric heating efficiency. The [C II]/FIR ratio shows weaker correlation with FIR luminosity. At low redshifts highly luminous galaxies tend to have warm dust, so the effects of dust temperature and luminosity are degenerate. Luminous galaxies at high redshifts show a range of dust temperatures, showing that [C II]/FIR correlates most strongly with dust temperature. The [C II] to mid-IR ratio for the HELLO sample is similar to the values seen for low-redshift galaxies, indicating that small grains and PAHs dominate the heating in the neutral ISM, although some of the high [CII]/FIR ratios may be due to turbulent heating.

  12. On-line estimation and compensation scheme for dead time and inverter nonlinearity independent of parameter variations in PMSM drive

    Science.gov (United States)

    Kim, Kyeong-Hwa

    2012-12-01

    A new on-line compensation scheme that can exactly estimate the dead time and inverter nonlinearity even under the parameter variations is proposed for a PWM inverter-fed permanent magnet synchronous motor drive. The proposed scheme is based on the fact that the sixth-order harmonic component in total disturbance estimated under the presence of various uncertainties is mainly caused by the dead time and inverter nonlinearity. The total disturbance due to the parameter variations as well as the dead time and inverter nonlinearity is estimated by the adaptive scheme. From this total disturbance, the sixth-order harmonic component is extracted through the harmonic analysis. The obtained sixth-order harmonic is processed by the PI controller to estimate the disturbance only caused by the dead time and inverter nonlinearity in the stationary reference frame. The effectiveness of the proposed scheme is verified through the comparative simulations and experiments using DSP TMS320F28335. Without requiring an additional hardware, the proposed scheme can effectively compensate the dead time and inverter nonlinearity even under the parameter variations.

  13. Diurnal and Interannual Variation in Absorption Lines of Isotopic Carbon Dioxide in Mars Atmosphere

    Science.gov (United States)

    Livengood, Timothy A.; Kostiuk, Theodor; Hewagama, Tilak; Kolasinski, John R.; Henning, Wade G.

    2015-11-01

    Groundbased observations of Mars in 2003, 2007, 2012, and 2014 have detected transitions of carbon dioxide containing the stable minor isotopes of oxygen and carbon as well as the primary isotopes, using the ultrahigh resolution spectrometer HIPWAC at the NASA Infrared Telescope Facility. The most well characterized minor isotope is O-18, due to strong lines and observational opportunities. The average estimated O-18/O-16 isotope ratio is roughly consistent with other in situ and remote spectroscopic measurements but demonstrates an additional feature in that the retrieved ratio appears to increase with greater ground surface temperature. These conclusions primarily come from analyzing a subset of the 2007 data. Additional observations have been acquired over a broad range of local time and meridional position to evaluate variability with respect to ground surface temperature. These additional observations include one run of measurements with C-13. These observations can be compared to local in situ measurements by the Curiosity rover to narrow the uncertainty in absolute isotope ratio and extend isotopic measurements to other regions and seasons on Mars. The relative abundance of carbon dioxide heavy isotopes on Mars is central to estimating the primordial atmospheric inventory on Mars. Preferential freeze-distillation of heavy isotopes means that any measurement of the isotope ratio can be only a lower limit on heavy isotope enrichment due to past and current loss to space.

  14. On a free-surface problem with moving contact line: From variational principles to stable numerical approximations

    Science.gov (United States)

    Fumagalli, Ivan; Parolini, Nicola; Verani, Marco

    2018-02-01

    We analyze a free-surface problem described by time-dependent Navier-Stokes equations. Surface tension, capillary effects and wall friction are taken into account in the evolution of the system, influencing the motion of the contact line - where the free surface hits the wall - and of the dynamics of the contact angle. The differential equations governing the phenomenon are first derived from the variational principle of minimum reduced dissipation, and then discretized by means of the ALE approach. The numerical properties of the resulting scheme are investigated, drawing a parallel with the physical properties holding at the continuous level. Some instability issues are addressed in detail, in the case of an explicit treatment of the geometry, and novel additional terms are introduced in the discrete formulation in order to damp the instabilities. Numerical tests assess the suitability of the approach, the influence of the parameters, and the effectiveness of the new stabilizing terms.

  15. Physiological basis of genetic variation in leaf photosynthesis among rice (Oryza sativa L.) introgression lines under drought and well-watered conditions

    Science.gov (United States)

    Yin, Xinyou

    2012-01-01

    To understand the physiological basis of genetic variation and resulting quantitative trait loci (QTLs) for photosynthesis in a rice (Oryza sativa L.) introgression line population, 13 lines were studied under drought and well-watered conditions, at flowering and grain filling. Simultaneous gas exchange and chlorophyll fluorescence measurements were conducted at various levels of incident irradiance and ambient CO2 to estimate parameters of a model that dissects photosynthesis into stomatal conductance (g s), mesophyll conductance (g m), electron transport capacity (J max), and Rubisco carboxylation capacity (V cmax). Significant genetic variation in these parameters was found, although drought and leaf age accounted for larger proportions of the total variation. Genetic variation in light-saturated photosynthesis and transpiration efficiency (TE) were mainly associated with variation in g s and g m. One previously mapped major QTL of photosynthesis was associated with variation in g s and g m, but also in J max and V cmax at flowering. Thus, g s and g m, which were demonstrated in the literature to be responsible for environmental variation in photosynthesis, were found also to be associated with genetic variation in photosynthesis. Furthermore, relationships between these parameters and leaf nitrogen or dry matter per unit area, which were previously found across environmental treatments, were shown to be valid for variation across genotypes. Finally, the extent to which photosynthesis rate and TE can be improved was evaluated. Virtual ideotypes were estimated to have 17.0% higher photosynthesis and 25.1% higher TE compared with the best genotype investigated. This analysis using introgression lines highlights possibilities of improving both photosynthesis and TE within the same genetic background. PMID:22888131

  16. The Virtual Observatory Service TheoSSA: Establishing a Database of Synthetic Stellar Flux Standards I. NLTE Spectral Analysis of the DA-Type White Dwarf G191-B2B *,**,***,****

    Science.gov (United States)

    Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

    2013-01-01

    Hydrogen-rich, DA-type white dwarfs are particularly suited as primary standard stars for flux calibration. State-of-the-art NLTE models consider opacities of species up to trans-iron elements and provide reliable synthetic stellar-atmosphere spectra to compare with observations. Aims. We will establish a database of theoretical spectra of stellar flux standards that are easily accessible via a web interface. Methods. In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. Results. TheoSSA is in operation and contains presently a variety of SEDs for DA-type white dwarfs. It will be extended in the near future and can host SEDs of all primary and secondary flux standards. The spectral analysis of G191-B2B has shown that our hydrostatic models reproduce the observations best at Teff =60 000 +/- 2000K and log g=7.60 +/- 0.05.We newly identified Fe vi, Ni vi, and Zn iv lines. For the first time, we determined the photospheric zinc abundance with a logarithmic mass fraction of -4.89 (7.5 × solar). The abundances of He (upper limit), C, N, O, Al, Si, O, P, S, Fe, Ni, Ge, and Sn were precisely determined. Upper abundance limits of about 10% solar were derived for Ti, Cr, Mn, and Co. Conclusions. The TheoSSA database of theoretical SEDs of stellar flux standards guarantees that the flux calibration of all astronomical data and cross-calibration between different instruments can be based on the same models and SEDs calculated with different model-atmosphere codes and are easy to compare.

  17. Comprehensive Identification and Bread-Making Quality Evaluation of Common Wheat Somatic Variation Line AS208 on Glutenin Composition.

    Directory of Open Access Journals (Sweden)

    Huiyun Liu

    Full Text Available High molecular weight glutenin subunits (HMW-GSs are important seed storage proteins in wheat (Triticum aestivum that determine wheat dough elasticity and processing quality. Clarification of the defined effectiveness of HMW-GSs is very important to breeding efforts aimed at improving wheat quality. To date, there have no report on the expression silencing and quality effects of 1Bx20 and 1By20 at the Glu-B1 locus in wheat. A wheat somatic variation line, AS208, in which both 1Bx20 and 1By20 at Glu-B1 locus were silenced, was developed recently in our laboratory. Evaluation of agronomic traits and seed storage proteins by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE and reversed-phase high performance liquid chromatography (RP-HPLC indicated that AS208 was highly similar to its parental cultivar Lunxuan987 (LX987, with the exception that the composition and expression of HMW-GSs was altered. The 1Bx20 and 1By20 in AS208 were further identified to be missing by polymerase chain reaction (PCR and quantitative real-time RT-PCR (qRT-PCR assays. Based on the PCR results for HMW-GS genes and their promoters in AS208 compared with LX987, 1Bx20 and 1By20 were speculated to be deleted in AS208 during in vitro culture. Quality analysis of this line with Mixograph, Farinograph, and Extensograph instruments, as well as analysis of bread-making quality traits, demonstrated that the lack of the genes encoding 1Bx20 and 1By20 caused various negative effects on dough processing and bread-making quality traits, including falling number, dough stability time, mixing tolerance index, crude protein values, wet gluten content, bread size, and internal cell structure. AS208 can potentially be used in the functional dissection of other HMW-GSs as a plant material with desirable genetic background, and in biscuit making industry as a high-quality weak gluten wheat source.

  18. Comprehensive Identification and Bread-Making Quality Evaluation of Common Wheat Somatic Variation Line AS208 on Glutenin Composition

    Science.gov (United States)

    Du, Lipu; Cao, Xinyou; Zhang, Xiaoxiang; Zhou, Yang; Yan, Yueming; Ye, Xingguo

    2016-01-01

    High molecular weight glutenin subunits (HMW-GSs) are important seed storage proteins in wheat (Triticum aestivum) that determine wheat dough elasticity and processing quality. Clarification of the defined effectiveness of HMW-GSs is very important to breeding efforts aimed at improving wheat quality. To date, there have no report on the expression silencing and quality effects of 1Bx20 and 1By20 at the Glu-B1 locus in wheat. A wheat somatic variation line, AS208, in which both 1Bx20 and 1By20 at Glu-B1 locus were silenced, was developed recently in our laboratory. Evaluation of agronomic traits and seed storage proteins by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and reversed-phase high performance liquid chromatography (RP-HPLC) indicated that AS208 was highly similar to its parental cultivar Lunxuan987 (LX987), with the exception that the composition and expression of HMW-GSs was altered. The 1Bx20 and 1By20 in AS208 were further identified to be missing by polymerase chain reaction (PCR) and quantitative real-time RT-PCR (qRT-PCR) assays. Based on the PCR results for HMW-GS genes and their promoters in AS208 compared with LX987, 1Bx20 and 1By20 were speculated to be deleted in AS208 during in vitro culture. Quality analysis of this line with Mixograph, Farinograph, and Extensograph instruments, as well as analysis of bread-making quality traits, demonstrated that the lack of the genes encoding 1Bx20 and 1By20 caused various negative effects on dough processing and bread-making quality traits, including falling number, dough stability time, mixing tolerance index, crude protein values, wet gluten content, bread size, and internal cell structure. AS208 can potentially be used in the functional dissection of other HMW-GSs as a plant material with desirable genetic background, and in biscuit making industry as a high-quality weak gluten wheat source. PMID:26765256

  19. The formation of the Milky Way halo and its dwarf satellites; a NLTE-1D abundance analysis. II. Early chemical enrichment

    Science.gov (United States)

    Mashonkina, L.; Jablonka, P.; Sitnova, T.; Pakhomov, Yu.; North, P.

    2017-12-01

    We present the non-local thermodynamic equilibrium (NLTE) abundances of up to 10 chemical species in a sample of 59 very metal-poor (VMP, -4 ≤ [Fe/H] ≾-2) stars in seven dwarf spheroidal galaxies (dSphs) and in the Milky Way (MW) halo. Our results are based on high-resolution spectroscopic datasets and homogeneous and accurate atmospheric parameters determined in Paper I. We show that once the NLTE effects are properly taken into account, all massive galaxies in our sample, that is, the MW halo and the classical dSphs Sculptor, Ursa Minor, Sextans, and Fornax, reveal a similar plateau at [α/Fe] ≃ 0.3 for each of the α-process elements: Mg, Ca, and Ti. We put on a firm ground the evidence for a decline in α/Fe with increasing metallicity in the Boötes I ultra-faint dwarf galaxy (UFD), that is most probably due to the ejecta of type Ia supernovae. For Na/Fe, Na/Mg, and Al/Mg, the MW halo and all dSphs reveal indistinguishable trends with metallicity, suggesting that the processes of Na and Al synthesis are identical in all systems, independent of their mass. The dichotomy in the [Sr/Ba] versus [Ba/H] diagram is observed in the classical dSphs, similarly to the MW halo, calling for two different nucleosynthesis channels for Sr. We show that Sr in the massive galaxies is well correlated with Mg suggesting a strong link to massive stars and that its origin is essentially independent of Ba, for most of the [Ba/H] range. Our three UFDs, that is Boötes I, UMa II, and Leo IV, are depleted in Sr and Ba relative to Fe and Mg, with very similar ratios of [Sr/Mg] ≃-1.3 and [Ba/Mg] ≃-1 on the entire range of their Mg abundances. The subsolar Sr/Ba ratios of Boötes I and UMa II indicate a common r-process origin of their neutron-capture elements. Sculptor remains the classical dSph, in which the evidence for inhomogeneous mixing in the early evolution stage, at [Fe/H] <-2, is the strongest. Full Tables 3 and 4 are only available at the CDS via anonymous ftp to

  20. Comparison of Cultivars and Seasonal Variation in Blueberry (Vaccinium Species) Leaf Extract on Adult T-Cell Leukemia Cell Line Growth Suppression.

    Science.gov (United States)

    Kai, Hisahiro; Fuse, Takuichi; Kunitake, Hisato; Morishita, Kazuhiro; Matsuno, Koji

    2014-06-30

    The inhibitory effects of blueberry leaves on the proliferation of adult T-cell leukemia (ATL) cell lines have previously been reported. A comparison of blueberry leaf extracts from different cultivars and seasonal variation were investigated regarding their effects on ATL cell line proliferation. The inhibitory effects of 80% ethanol leaf extracts from different blueberry cultivars collected from April to December in 2006 or 2008 were evaluated using two ATL cell lines. The bioactivities of leaf extracts of rabbit-eye blueberry (Vaccinium virgatum Aiton; RB species), southern highbush blueberry (V. spp.; SB species), northern highbush blueberry (V. corymbosum L.; NB species), and wild blueberry (V. bracteatum Thunb.; WB species) were compared. Of these, leaves of the RB species collected in December showed a significantly stronger inhibitory effect in both cell lines than the SB, NB, or WB species. These results suggest elevated biosynthesis of ATL-preventative bioactive compounds in the leaves of the RB species before the defoliation season.

  1. Associations between genetic variation in one-carbon metabolism and LINE-1 DNA methylation in histologically normal breast tissues

    Science.gov (United States)

    Genome-wide DNA hypomethylation is an early event in the carcinogenic process. Percent methylation of long interspersed nucleotide element-1 (LINE-1) is a biomarker of genome-wide methylation and is a potential biomarker for breast cancer. Understanding factors associated with percent LINE-1 DNA met...

  2. Apparatus and Method for Compensating for Process, Voltage, and Temperature Variation of the Time Delay of a Digital Delay Line

    Science.gov (United States)

    Seefeldt, James (Inventor); Feng, Xiaoxin (Inventor); Roper, Weston (Inventor)

    2013-01-01

    A process, voltage, and temperature (PVT) compensation circuit and a method of continuously generating a delay measure are provided. The compensation circuit includes two delay lines, each delay line providing a delay output. The two delay lines may each include a number of delay elements, which in turn may include one or more current-starved inverters. The number of delay lines may differ between the two delay lines. The delay outputs are provided to a combining circuit that determines an offset pulse based on the two delay outputs and then averages the voltage of the offset pulse to determine a delay measure. The delay measure may be one or more currents or voltages indicating an amount of PVT compensation to apply to input or output signals of an application circuit, such as a memory-bus driver, dynamic random access memory (DRAM), a synchronous DRAM, a processor or other clocked circuit.

  3. SCRIC: a code dedicated to the detailed emission and absorption of heterogeneous NLTE plasmas; application to xenon EUV sources; SCRIC: un code pour calculer l'absorption et l'emission detaillees de plasmas hors equilibre, inhomogenes et etendus; application aux sources EUV a base de xenon

    Energy Technology Data Exchange (ETDEWEB)

    Gaufridy de Dortan, F. de

    2006-07-01

    Nearly all spectral opacity codes for LTE and NLTE plasmas rely on configurations approximate modelling or even supra-configurations modelling for mid Z plasmas. But in some cases, configurations interaction (either relativistic and non relativistic) induces dramatic changes in spectral shapes. We propose here a new detailed emissivity code with configuration mixing to allow for a realistic description of complex mid Z plasmas. A collisional radiative calculation. based on HULLAC precise energies and cross sections. determines the populations. Detailed emissivities and opacities are then calculated and radiative transfer equation is resolved for wide inhomogeneous plasmas. This code is able to cope rapidly with very large amount of atomic data. It is therefore possible to use complex hydrodynamic files even on personal computers in a very limited time. We used this code for comparison with Xenon EUV sources within the framework of nano-lithography developments. It appears that configurations mixing strongly shifts satellite lines and must be included in the description of these sources to enhance their efficiency. (author)

  4. VizieR Online Data Catalog: NLTE spectral analysis of white dwarf G191-B2B (Rauch+, 2013)

    Science.gov (United States)

    Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

    2013-08-01

    In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. (3 data files).

  5. Influence of a variation in the position of the arms on the sagittal connection of the gravity line with the spinal structures.

    Science.gov (United States)

    Legaye, Jean; Duval-Beaupere, Ginette

    2017-11-01

    To evaluate the influence of the position of the arms on the location of the body's gravity line. The sagittal balance of the pelvi-spinal unit is organized so that the gravity line is localized in a way that limits the mechanical loads and the muscle efforts. This position of the gravity line was analyzed in vivo, in standing position, the arms dangling, by the barycentremeter, a gamma rays scanner. Then, several teams had the same purpose but using a force platform combined with radiographies. Their results differed significantly among themselves and with the data of the barycentremetry. However, in these studies, the positions of the arms varied noticeably, either slightly bent forwards on a support, or the fingers on the clavicles or on the cheeks. We estimated, for each varied posture of the arms, the sagittal coordinates of the masses of the upper limbs and their influence on the anatomical position of the gravity line of the whole body. Using a simple equation and the data of the barycentremeter, we observed that the variations in the location of the gravity line were proportionally connected to the changes of the sagittal position of the mass of the upper limbs induced by the various positions of the arms. We conclude in a validation of the data of the barycentremeter, as well as of the data obtained by the force platforms as long as the artifact of the position of the arms is taken into account.

  6. 40 CFR 53.55 - Test for effect of variations in power line voltage and ambient temperature.

    Science.gov (United States)

    2010-07-01

    ... requirements are met. (2) Variable voltage AC power transformer, range 100 Vac to 130 Vac, with sufficient... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Test for effect of variations in power... METHODS Procedures for Testing Physical (Design) and Performance Characteristics of Reference Methods and...

  7. Transgressive variation for yield components measured throughout the growth cycle of Jefferson rice (Oryza sativa) x O. rufipogon introgression lines

    Science.gov (United States)

    Previous studies demonstrated alleles introduced into elite rice (Oryza sativa) cultivars from the wild ancestral species, O. rufipogon, enhanced yield and yield components as a result of transgressive variation. A study was conducted to unveil phenological and agronomic mechanisms that underlie in...

  8. Transgressive variation for yield components and dynamic traits in Jefferson (Oryza sativa) x O. rufipogon introgression lines

    Science.gov (United States)

    Alleles from wild progenitors of crops can be a source of transgressive variation in modern cultivars. Introgressions from the Oryza rufipogon donor (IRGC104591) in an O. sativa tropical japonica cultivar (Jefferson) were shown to confer a yield advantage in multi-location field trials. Yield loci...

  9. Dependence of flow variations on changes in aerodynamic resistances in underground mine ventilation systems with line-parallel branch connections

    Energy Technology Data Exchange (ETDEWEB)

    Vuletic, V.

    1980-01-01

    The parameters of ventilation systems which affect the interdependence of flow variations and changes of resistance in individual branches of the system are discussed. The investigation was carried out by simulation on an analogue computer. (11 refs.) (In Serbo-Croat)

  10. The virtual observatory service TheoSSA: Establishing a database of synthetic stellar flux standards. I. NLTE spectral analysis of the DA-type white dwarf G191-B2B

    Science.gov (United States)

    Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

    2013-12-01

    Context. Hydrogen-rich, DA-type white dwarfs are particularly suited as primary standard stars for flux calibration. State-of-the-art NLTE models consider opacities of species up to trans-iron elements and provide reliable synthetic stellar-atmosphere spectra to compare with observations. Aims: We will establish a database of theoretical spectra of stellar flux standards that are easily accessible via a web interface. Methods: In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. Results: TheoSSA is in operation and contains presently a variety of SEDs for DA-type white dwarfs. It will be extended in the near future and can host SEDs of all primary and secondary flux standards. The spectral analysis of G191-B2B has shown that our hydrostatic models reproduce the observations best at and log g = 7.60 ± 0.05. We newly identified Fe vi, Ni vi, and Zn iv lines. For the first time, we determined the photospheric zinc abundance with a logarithmic mass fraction of -4.89 (7.5 × solar). The abundances of He (upper limit), C, N, O, Al, Si, O, P, S, Fe, Ni, Ge, and Sn were precisely determined. Upper abundance limits of about 10% solar were derived for Ti, Cr, Mn, and Co. Conclusions: The TheoSSA database of theoretical SEDs of stellar flux standards guarantees that the flux calibration of all astronomical data and cross-calibration between different instruments can be based on the same models and SEDs calculated with different model-atmosphere codes and are easy to compare. Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope

  11. Do laboratory frontal crash test programs predict driver fatality risk? Evidence from within vehicle line variation in test ratings.

    Science.gov (United States)

    Harless, David W; Hoffer, George E

    2007-09-01

    A number of studies have examined whether the National Highway Traffic Safety Administration's (NHTSA) frontal crash test results reliably indicate the risk of fatality or injury in serious crashes. The conclusions of these studies are mixed. Generally, studies that examine crashes in the circumstances as close as possible to those of the laboratory test find that crash test results do predict real-world risk, but studies of crashes outside those specific circumstances find either no support for the predictive validity of crash test results or limited support with important inconsistencies. We provide a new test of the predictive validity of the crash test results using information from multiple crash tests within vehicle lines, thus controlling for systematic differences in driver behavior across vehicle lines. Among drivers of passenger cars, we find large, statistically significant differences in fatality risk for vehicles with one- to four-star NHTSA ratings versus a five-star rating. We also examine the Insurance Institute for Highway Safety's frontal offset crash test, though our sample of vehicle lines tested twice or more is considerably smaller than for NHTSA ratings. Our results also support the predictive validity of the frontal offset crash test results for passenger cars, but not for trucks.

  12. Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines

    Directory of Open Access Journals (Sweden)

    Valerio Pazienza

    2012-01-01

    Full Text Available Carcinogenesis is related to the loss of homeostatic control of cellular processes regulated by transcriptional circuits and epigenetic mechanisms. Among these, the activities of peroxisome proliferator-activated receptors (PPARs and DNA methyltransferases (DNMTs are crucial and intertwined. PPARγ is a key regulator of cell fate, linking nutrient sensing to transcription processes, and its expression oscillates with circadian rhythmicity. Aim of our study was to assess the periodicity of PPARγ and DNMTs in pancreatic cancer (PC. We investigated the time-related patterns of PPARG, DNMT1, and DNMT3B expression monitoring their mRNA levels by qRT-PCR at different time points over a 28-hour span in BxPC-3, CFPAC-1, PANC-1, and MIAPaCa-2 PC cells after synchronization with serum shock. PPARG and DNMT1 expression in PANC-1 cells and PPARG expression in MIAPaCa-2 cells were characterized by a 24 h period oscillation, and a borderline significant rhythm was observed for the PPARG, DNMT1, and DNMT3B expression profiles in the other cell lines. The time-qualified profiles of gene expression showed different shapes and phase relationships in the PC cell lines examined. In conclusion, PPARG and DNMTs expression is characterized by different time-qualified patterns in cell lines derived from human PC, and this heterogeneity could influence cell phenotype and human disease behaviour.

  13. Pulsation-induced atmospheric dynamics in M-type AGB stars. Effects on wind properties, photometric variations and near-IR CO line profiles

    Science.gov (United States)

    Liljegren, S.; Höfner, S.; Eriksson, K.; Nowotny, W.

    2017-09-01

    Context. Wind-driving in asymptotic giant branch (AGB) stars is commonly attributed to a two-step process. First, matter in the stellar atmosphere is levitated by shock waves, induced by stellar pulsation, and second, this matter is accelerated by radiation pressure on dust, resulting in a wind. In dynamical atmosphere and wind models the effects of the stellar pulsation are often simulated by a simplistic prescription at the inner boundary. Aims: We test a sample of dynamical models for M-type AGB stars, for which we kept the stellar parameters fixed to values characteristic of a typical Mira variable but varied the inner boundary condition. The aim was to evaluate the effect on the resulting atmosphere structure and wind properties. The results of the models are compared to observed mass-loss rates and wind velocities, photometry, and radial velocity curves, and to results from 1D radial pulsation models. The goal is to find boundary conditions which give realistic atmosphere and wind properties. Methods: Dynamical atmosphere models are calculated, using the DARWIN code for different combinations of photospheric velocities and luminosity variations. The inner boundary is changed by introducing an offset between maximum expansion of the stellar surface and the luminosity and/or by using an asymmetric shape for the luminosity variation. Ninety-nine different combinations of theses two changes are tested. Results: The model atmospheres are very sensitive to the inner boundary. Models that resulted in realistic wind velocities and mass-loss rates, when compared to observations, also produced realistic photometric variations. For the models to also reproduce the characteristic radial velocity curve present in Mira stars (derived from CO Δv = 3 lines), an overall phase shift of 0.2 between the maxima of the luminosity and radial variation had to be introduced. This is a larger phase shift than is found by 1D radial pulsation models. Conclusions: We find that a group

  14. iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types

    Directory of Open Access Journals (Sweden)

    Athanasia D. Panopoulos

    2017-04-01

    Full Text Available Large-scale collections of induced pluripotent stem cells (iPSCs could serve as powerful model systems for examining how genetic variation affects biology and disease. Here we describe the iPSCORE resource: a collection of systematically derived and characterized iPSC lines from 222 ethnically diverse individuals that allows for both familial and association-based genetic studies. iPSCORE lines are pluripotent with high genomic integrity (no or low numbers of somatic copy-number variants as determined using high-throughput RNA-sequencing and genotyping arrays, respectively. Using iPSCs from a family of individuals, we show that iPSC-derived cardiomyocytes demonstrate gene expression patterns that cluster by genetic background, and can be used to examine variants associated with physiological and disease phenotypes. The iPSCORE collection contains representative individuals for risk and non-risk alleles for 95% of SNPs associated with human phenotypes through genome-wide association studies. Our study demonstrates the utility of iPSCORE for examining how genetic variants influence molecular and physiological traits in iPSCs and derived cell lines.

  15. A framework to quantify karyotype variation associated with CHO cell line instability at a single-cell level.

    Science.gov (United States)

    Baik, Jong Youn; Lee, Kelvin H

    2017-05-01

    Chinese hamster ovary (CHO) cells, the major mammalian host cells for biomanufacturing of therapeutic proteins, have been extensively investigated to enhance productivity and product quality. However, cell line instability resulting in unexpected changes in productivity or product quality continues to be a challenge. Based on previous reports about causes and characteristics of production instability, we hypothesized that chromosomal rearrangements due to genomic instability are associated with production instability and that these events can be characterized. We developed a production instability model using secreted alkaline phosphatase (SEAP)-expressing CHO cells (CHO-SEAP) as well as a framework to quantify chromosomal rearrangements by karyotyping. In the absence of methotrexate (MTX), CHO-SEAP cells exhibited a slightly increased growth rate, a significantly decreased specific productivity, and changes in the chromosomal rearrangement ratio of seven chromosomes. In contrast, when MTX was re-introduced, the growth rate and SEAP productivity reversed to the initial values, demonstrating the reversibility of production instability in CHO-SEAP cells. Fluorescence in situ hybridization analysis identified that the SEAP genes were incorporated in the chromosomal rearrangement (insertion) part of the der(Z9) chromosome. Karyotype analysis indicated that the insertion ratio of the der(Z9) chromosome decreased in the CHO-SEAP cells grown without MTX, demonstrating a correlation between chromosomal rearrangement and production instability. Our results support a mechanism for production instability, wherein a randomly generated chromosomal rearrangement (or genotype) results in cells with a growth advantage that is also associated with non (or low)-producing traits. As a result, the non-producing cells grow faster and thereby outgrow the producing population. Biotechnol. Bioeng. 2017;114: 1045-1053. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Detection of emission in the Si I 1082.7 nm line core in sunspot umbrae

    Science.gov (United States)

    Orozco Suárez, D.; Quintero Noda, C.; Ruiz Cobo, B.; Collados Vera, M.; Felipe, T.

    2017-11-01

    Context. Determining empirical atmospheric models for the solar chromosphere is difficult since it requires the observation and analysis of spectral lines that are affected by non-local thermodynamic equilibrium (NLTE) effects. This task is especially difficult in sunspot umbrae because of lower continuum intensity values in these regions with respect to the surrounding brighter granulation. Umbral data is therefore more strongly affected by the noise and by the so-called scattered light, among other effects. Aims: The purpose of this study is to analyze spectropolarimetric sunspot umbra observations taken in the near-infrared Si I 1082.7 nm line taking NLTE effects into account. Interestingly, we detected emission features at the line core of the Si I 1082.7 nm line in the sunspot umbra. Here we analyze the data in detail and offer a possible explanation for the Si I 1082.7 nm line emission. Methods: Full Stokes measurements of a sunspot near disk center in the near-infrared spectral range were obtained with the GRIS instrument installed at the German GREGOR telescope. A point spread function (PSF) including the effects of the telescope, the Earth's atmospheric seeing, and the scattered light was constructed using prior Mercury observations with GRIS and the information provided by the adaptive optics system of the GREGOR telescope during the observations. The data were then deconvolved from the PSF using a principal component analysis deconvolution method and were analyzed via the NICOLE inversion code, which accounts for NLTE effects in the Si I 1082.7 nm line. The information of the vector magnetic field was included in the inversion process. Results: The Si I 1082.7 nm line seems to be in emission in the umbra of the observed sunspot after the effects of scattered light (stray light coming from wide angles) are removed. We show how the spectral line shape of umbral profiles changes dramatically with the amount of scattered light. Indeed, the continuum levels

  17. An evaluation of relation between the relative parallelism of occlusal plane to ala-tragal line and variation in the angulation of Po-Na-ANS angle in dentulous subjects: A cephalometric study.

    Science.gov (United States)

    Shetty, Sanath; Shenoy, K Kamalakanth; Ninan, Justin; Mahaseth, Pranay

    2015-01-01

    The aim was to evaluate if any correlation exists between variation in angulation of Po-Na-ANS angle and relative parallelism of the occlusal plane to the different tragal levels of the ear in dentulous subjects. A total of 200 subjects were selected for the study. A custom made occlusal plane analyzer was used to determine the posterior point of the ala-tragal line. The lateral cephalogram was shot for each of the subjects. The points Porion, Nasion, and Anterior Nasal Spine were located and the angle formed between these points was measured. Fischer's exact test was used to find the correlation between Po-Na-ANS angle and relative parallelism of the occlusal plane to the ala-tragal line at different tragal levels. Statistical analysis showed no significant correlation between Po-Na-ANS angle and relative parallelism of an occlusal plane at different tragal levels, and an inferior point on the tragus was the most common. Irrespective of variations in the Po-Na-ANS angle, no correlation exists between the variation in the angulations of Po-Na-ANS angle and the relative parallelism of occlusal plane to the ala-tragal line at different tragal levels. Furthermore, in a large number of subjects (54%), the occlusal plane was found parallel to a line joining the inferior border of the ala of the nose and the inferior part of the tragus.

  18. Si III OV Bright Line of Scattering Polarized Light That Has Been Observed in the CLASP and Its Center-to-Limb Variation

    Science.gov (United States)

    Katsukawa, Yukio; Ishikawa, Ryoko; Kano, Ryohei; Kubo, Masahito; Noriyuki, Narukage; Kisei, Bando; Hara, Hirohisa; Yoshiho, Suematsu; Goto, Motouji; Ishikawa, Shinnosuke; hide

    2017-01-01

    The CLASP (Chromospheric Lyman-Alpha Spectro- Polarimeter) rocket experiment, in addition to the ultraviolet region of the Ly alpha emission line (121.57 nm), emission lines of Si III (120.65 nm) and OV (121.83 nm) is can be observed. These are optically thin line compared to a Ly alpha line, if Rarere captured its polarization, there is a possibility that dripping even a new physical diagnosis chromosphere-transition layer. In particular, OV bright light is a release from the transition layer, further, three P one to one S(sub 0) is a forbidden line (cross-triplet transition between lines), it was not quite know whether to polarization.

  19. Evaluation and Modeling of the Variation of Electromagnetic Field on the Cross Section of a Transmission Line Using Finite Difference Method

    Directory of Open Access Journals (Sweden)

    Jorge I. Silva O.

    2015-06-01

    Full Text Available This paper present a purpose to characterize power lines in order to identify level of operation since the power grid planning. In order to model a power line was required the use of computational tools to generate a mathematical model in MATLAB, which was based on the finite difference method and represent the electromagnetic field (EMF contribution. The results were contrasted with real and measured values taken from a cross section of a power line that was previously modeled. Statistical analysis showed an accurate estimation of the electric and magnetic field emitted by the line identifying the same shape of the plotted curve and values in an acceptable range.

  20. Variation of Water-Soluble Carbohydrates and Grain Yield in Iranian Cold Barley Promising Lines Under Well-Watered and Water Stress Conditions

    Directory of Open Access Journals (Sweden)

    Mohammadi Soleiman

    2014-10-01

    Full Text Available In order to evaluate promising lines in terms of grain yield and water-soluble carbohydrates remobiliza-tion, an experiment with fifteen promising lines and two checks was carried out under full irrigation and terminal water stress conditions at Miyandoab Agricultural Research and Natural Resources Station. Mobilized dry matter content and remobilization percentage from shoot to grain under water deficit (177mg(11.2% were greater than those under well watering condition. The lowest (110 mg and the highest (260mg mobilized dry matter to grain were obtained for C-79-18 and C-83-15lines, respectively. Water deficit reduced grain yield of barley genotypes by 200-1600 kg/ha, and mean grain yield reduction was 800 kg/ha. Line 14 with 5.880and 5.300t/ha grain yield in favorable and water stress conditions was superior to the other lines. Under water deficit condition, line 14 had greater grain yieldby20% and 38% than the Bahman and Makouee cultivars, respectively. The results showed that greater grain yield in tolerant lines under water deficit was due to remobilization of unstructured carbohydrates from shoot to grain. Thus, it seems that selection of lines with higher translocated dry matter and contribution of pre-anthesis assimilate in grain filling under water stress, the suitable way for achieving genotypes with high grain yield under water stress condition.

  1. Human intestinal and lung cell lines exposed to beta-carotene show a large variation in intracellular levels of beta-carotene and its metabolites

    NARCIS (Netherlands)

    Franssen-Hal, van N.L.W.; Bunschoten, J.E.; Venema, D.P.; Hollman, P.C.H.; Riss, G.; Keijer, J.

    2005-01-01

    Although in vitro models are often used in ß-carotene research, knowledge about the uptake and metabolism of ß-carotene in cell lines is lacking. We measured by HPLC the intracellular levels of ß-carotene and its metabolites in 9 human intestinal and lung cell lines after exposure to 1 ¿M ß-carotene

  2. Accuracy of ultrasound B-lines score and E/Ea ratio to estimate extravascular lung water and its variations in patients with acute respiratory distress syndrome.

    Science.gov (United States)

    Bataille, Benoît; Rao, Guillaume; Cocquet, Pierre; Mora, Michel; Masson, Bruno; Ginot, Jean; Silva, Stein; Moussot, Pierre-Etienne

    2015-02-01

    Extravascular lung water (EVLW) could increase by permeability pulmonary oedema, cardiogenic oedema, or both. Transthoracic echocardiography examination of a patient allows quantifying B-lines, originating from water-thickened interlobular septa, and the E/Ea ratio, related to pulmonary capillary wedge pressure. The aim of our study was to assess the correlation and the trending ability between EVLW measured by transpulmonary thermodilution and the B-lines score or the E/Ea ratio in patients with ARDS. Twenty-six intensive care unit patients were prospectively included. B-lines score was obtained from four ultrasound zones (anterior and lateral chest on left and right hemithorax). E/Ea was measured from the apical four-chamber view. EVLW was compared with the B-lines score and the E/Ea ratio. A linear mixed effect model was used to take account the repeated measurements. A p value10 ml/kg, with an AUC equal to 0.86 (0.76-0.93). The gray zone approach identified a range of B-lines between four and seven for which EVLW>10 ml/kg could not be predicted reliably. The correlation between ultrasound B-lines and EVLW was significant, but the B-lines score was not able to track EVLW changes reliably.

  3. FASTWIND reloaded: Complete comoving frame transfer for ``all'' contributing lines

    Science.gov (United States)

    Puls, Joachim

    2017-11-01

    FASTWIND is a unified NLTE atmosphere/spectrum synthesis code originally designed (and frequently used) for the optical/IR spectroscopic analysis of massive stars with winds. Until the previous version (v10), the line transfer for background elements (mostly from the iron-group) was performed in an approximate way, by calculating the individual line-transitions in a single-line Sobolev or comoving frame approach, and by adding up the individual opacities and source functions to quasi-continuum quantities that are used to determine the radiation field for the complete spectrum (see Puls et al. 2005, A&A 435, 669, and updates). We have now updated this approach (v11) and calculate, for all contributing lines (from elements H to Zn), the radiative transfer in the comoving frame, thus also accounting for line-overlap effects in an ``exact'' way. Related quantities such as temperature, radiative acceleration and formal integral have been improved in parallel. For a typical massive star atmospheric model, the computation times (from scratch, and for a modern desktop computer) are 1.5 h for the atmosphere/NLTE part, and 30 to 45 minutes (when not parallelized) for the formal integral (i.e., SED and normalized flux) in the ranges 900 to 2000 and 3800 to 7000 Å(Δλ = 0.03 Å). We compare our new with analogous results from the alternative code CMFGEN (Hillier & Miller 1998, ApJ 496, 407, and updates), for a grid consisting of 5 O-dwarf and 5 O-supergiant models of different spectral subtype. In most cases, the agreement is very good or even excellent (i.e., for the radiative acceleration), though also certain differences can be spotted. A comparison with results from the previous, approximate method shows equally good agreement, though also here some differences become obvious. Besides the possibility to calculate the (total) radiative acceleration, the new FASTWIND version will allow us to investigate the UV-part of the spectrum in parallel with the optical/IR domain.

  4. Effect of line-mixing on the emissions in the infrared CO2 bands in the middle and upper atmosphere of Earth

    Science.gov (United States)

    Ogibalov, Vladimir

    Radiative transfer in the infrared (IR) ro-vibrational bands of CO2 molecules under non-local thermodynamic equilibrium (NLTE) conditions is an important factor in establishing the global heat balance, structure, and dynamical properties of the mesosphere and lower thermosphere (MLT) of Earth. Moreover, the emissions in the IR bands of CO2 are used for remote sensing of the kinetic temperature and the CO2 abundance in the MLT altitude interval. These reasons require developing both more sophisticated models for estimating the values of non-equilibrium populations of the excited vibrational states of CO2 in the MLT and more detailed radiative transfer schemes. The validity of estimating the cooling rate in the 15 µm CO2 band depends on various input data used. In particular, spectroscopic parameters and a shape of absorption coefficient adopted for lines of the IR CO2 bands are of great importance. Till present time in the NLTE models developed to calculate IR emissions in the CO2 bands, it has been supposed that the absorption coefficient in the band is a simple sum of absorption coefficients of lines included at the given frequency and that the spectral shape of the absorption coefficient in every line is described by the Voigt function. However, it is known, when lines overlap in frequency (especially, in Q-branches of CO2 bands), the spectral band shape calculated according to this approximation could deviate to a large extent from the experimental one due to the effect of line-mixing (LM). This makes the LM-effect be potentially important for solving the NLTE problem of the CO2 bands. In the present study, the current version of computer code realizing the NLTE model for the IR emissions of CO2 in the MLT [1-2] has been further improved to incorporate the LMeffect. The Adjusted Branch Coupling method has been applied to simulate the experimental shape of the absorption coefficient within the spectral interval of the 15 µm band [3]. For a set of atmospheric

  5. Variation in drug sensitivity of malignant mesothelioma cell lines with substantial effects of selenite and bortezomib, highlights need for individualized therapy.

    Directory of Open Access Journals (Sweden)

    Adam Szulkin

    Full Text Available Malignant mesothelioma cells have an epithelioid or sarcomatoid morphology, both of which may be present in the same tumor. The sarcomatoid phenotype is associated with worse prognosis and heterogeneity of mesothelioma cells may contribute to therapy resistance, which is often seen in mesothelioma. This study aimed to investigate differences in sensitivity between mesothelioma cell lines to anti-cancer drugs. We studied two novel drugs, selenite and bortezomib and compared their effect to four conventional drugs. We also investigated the immunoreactivity of potential predictive markers for drug sensitivity; Pgp, MRP-1, ERCC1, RRM1, TS, xCT and proteasome 20S subunit.We treated six mesothelioma cell lines with selenite, bortezomib, carboplatin, pemetrexed, doxorubicin or gemcitabine as single agents and in combinations. Viability was measured after 24 and 48 hours. Immunocytochemistry was used to detect predictive markers.As a single agent, selenite was effective on four out of six cell lines, and in combination with bortezomib yielded the greatest response in the studied mesothelioma cell lines. Cells with an epithelioid phenotype were generally more sensitive to the different drugs than the sarcomatoid cells. Extensive S-phase arrest was seen in pemetrexed-sensitive cell lines. MRP-1 predicted sensitivity of cell lines to treatment with carboplatin and xCT predicted pemetrexed effect.The observed heterogeneity in sensitivity of mesothelioma cell lines with different morphology highlights the need for more individualized therapy, requiring development of methods to predict drug sensitivity of individual tumors. Selenite and bortezomib showed a superior effect compared to conventional drugs, motivating clinical testing of these agents as future treatment regime components for patients with malignant mesothelioma.

  6. Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations.

    Science.gov (United States)

    Sun, Yi; Zhang, Wei; Chen, Yunqin; Ma, Qin; Wei, Jia; Liu, Qi

    2016-02-23

    Clinical responses to anti-cancer therapies often only benefit a defined subset of patients. Predicting the best treatment strategy hinges on our ability to effectively translate genomic data into actionable information on drug responses. To achieve this goal, we compiled a comprehensive collection of baseline cancer genome data and drug response information derived from a large panel of cancer cell lines. This data set was applied to identify the signature genes relevant to drug sensitivity and their resistance by integrating CNVs and the gene expression of cell lines with in vitro drug responses. We presented an efficient in-silico pipeline for integrating heterogeneous cell line data sources with the simultaneous modeling of drug response values across all the drugs and cell lines. Potential signature genes correlated with drug response (sensitive or resistant) in different cancer types were identified. Using signature genes, our collaborative filtering-based drug response prediction model outperformed the 44 algorithms submitted to the DREAM competition on breast cancer cells. The functions of the identified drug response related signature genes were carefully analyzed at the pathway level and the synthetic lethality level. Furthermore, we validated these signature genes by applying them to the classification of the different subtypes of the TCGA tumor samples, and further uncovered their in vivo implications using clinical patient data. Our work may have promise in translating genomic data into customized marker genes relevant to the response of specific drugs for a specific cancer type of individual patients.

  7. Non-LTE line formation of Fe in late-type stars - IV. Modelling of the solar centre-to-limb variation in 3D

    DEFF Research Database (Denmark)

    Lind, K.; Amarsi, A. M.; Asplund, M.

    2017-01-01

    Our ability to model the shapes and strengths of iron lines in the solar spectrum is a critical test of the accuracy of the solar iron abundance, which sets the absolute zero-point of all stellar metallicities. We use an extensive 463-level Fe atom with new photoionization cross-sections for Fe I...

  8. Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel

    Directory of Open Access Journals (Sweden)

    Eastman Alan

    2011-05-01

    Full Text Available Abstract Background The Mre11/Rad50/Nbs1 (MRN complex is a regulator of cell cycle checkpoints and DNA repair. Defects in MRN can lead to defective S-phase arrest when cells are damaged. Such defects may elicit sensitivity to selected drugs providing a chemical synthetic lethal interaction that could be used to target therapy to tumors with these defects. The goal of this study was to identify these defects in the NCI60 panel of cell lines and identify compounds that might elicit selective cytotoxicity. Methods We screened the NCI60 panel in search of cell lines that express low levels of MRN proteins, or that fail to arrest in S-phase in response to the topisomerase I inhibitor SN38. The NCI COMPARE program was used to discover compounds that preferentially target cells with these phenotypes. Results HCT116 cells were initially identified as defective in MRN and S phase arrest. Transfection with Mre11 also elevated Rad50 and Nbs1, and rescued the defective S-phase arrest. Cells of the NCI60 panel exhibited a large range of protein expression but a strong correlation existed between Mre11, Rad50 and Nbs1 consistent with complex formation determining protein stability. Mre11 mRNA correlated best with protein level suggesting it was the primary determinant of the overall level of the complex. Three other cell lines failed to arrest in response to SN38, two of which also had low MRN. However, other cell lines with low MRN still arrested suggesting low MRN does not predict an inability to arrest. Many compounds, including a family of benzothiazoles, correlated with the failure to arrest in S phase. The activity of benzothiazoles has been attributed to metabolic activation and DNA alkylation, but we note several cell lines in which sensitivity does not correlate with metabolism. We propose that the checkpoint defect imposes an additional mechanism of sensitivity on cells. Conclusions We have identified cells with possible defects in the MRN complex

  9. CO mass upper limits in the Fomalhaut ring - the importance of NLTE excitation in debris discs and future prospects with ALMA

    Science.gov (United States)

    Matrà, L.; Panić, O.; Wyatt, M. C.; Dent, W. R. F.

    2015-03-01

    In recent years, gas has been observed in an increasing number of debris discs, though its nature remains to be determined. Here, we analyse CO molecular excitation in optically thin debris discs, and search Atacama Large Millimeter/submillimeter Array (ALMA) Cycle-0 data for CO J = 3-2 emission in the Fomalhaut ring. No significant line emission is observed; we set a 3σ upper limit on the integrated line flux of 0.16 Jy km s-1. We show a significant dependence of the CO excitation on the density of collisional partners n, on the gas kinetic temperature Tk and on the ambient radiation field J, suggesting that assumptions widely used for protoplanetary discs (e.g. local thermodynamic equilibrium, LTE) do not necessarily apply to their low density debris counterparts. When applied to the Fomalhaut ring, we consider a primordial origin scenario where H2 dominates collisional excitation of CO, and a secondary origin scenario dominated by e- and H2O. In either scenario, we obtain a strict upper limit on the CO mass of 4.9 × 10-4 M⊕. This arises in the non-LTE regime, where the excitation of the molecule is determined solely by the well-known radiation field. In the secondary scenario, assuming any CO present to be in steady state allows us to set an upper limit of ˜55 per cent on the CO/H2O ice ratio in the parent planetesimals. This could drop to ˜3 per cent if LTE applies, covering the range observed in Solar system comets (0.4-30 per cent). Finally, in light of our analysis, we present prospects for CO detection and characterization in debris discs with ALMA.

  10. A protocol to correct for intra- and interspecific variation in tail hair growth to align isotope signatures of segmentally cut tail hair to a common time line.

    Science.gov (United States)

    Burnik Šturm, Martina; Pukazhenthi, Budhan; Reed, Dolores; Ganbaatar, Oyunsaikhan; Sušnik, Stane; Haymerle, Agnes; Voigt, Christian C; Kaczensky, Petra

    2015-06-15

    In recent years, segmental stable isotope analysis of hair has been a focus of research in animal dietary ecology and migration. To correctly assign tail hair segments to seasons or even Julian dates, information on tail hair growth rates is a key parameter, but is lacking for most species. We (a) reviewed the literature on tail hair growth rates in mammals; b) made own measurements of three captive equid species; (c) measured δ(2)H, δ(13)C and δ(15)N values in sequentially cut tail hairs of three sympatric, free-ranging equids from the Mongolian Gobi, using isotope ratio mass spectrometry (IRMS); and (d) collected environmental background data on seasonal variation by measuring δ(2)H values in precipitation by IRMS and by compiling pasture productivity measured by remote sensing via the normalized difference vegetation index (NDVI). Tail hair growth rates showed significant inter- and intra-specific variation making temporal alignment problematic. In the Mongolian Gobi, high seasonal variation of δ(2)H values in precipitation results in winter lows and summer highs of δ(2)H values of available water sources. In water-dependent equids, this seasonality is reflected in the isotope signatures of sequentially cut tails hairs. In regions which are subject to strong seasonal patterns we suggest identifying key isotopes which show strong seasonal variation in the environment and can be expected to be reflected in the animal tissue. The known interval between the maxima and minima of these isotope values can then be used to correctly temporally align the segmental stable isotope signature for each individual animal. © 2015 The Authors. Rapid Communications in Mass Spectrometry published by John Wiley & Sons Ltd.

  11. De novo genetic variation associated with retrotransposon activation, genomic rearrangements and trait variation in a recombinant inbred line population of Brassica napus derived from interspecific hybridization with Brassica rapa.

    Science.gov (United States)

    Zou, Jun; Fu, Donghui; Gong, Huihui; Qian, Wei; Xia, Wei; Pires, J Chris; Li, Ruiyuan; Long, Yan; Mason, Annaliese S; Yang, Tae-Jin; Lim, Yong P; Park, Beom S; Meng, Jinling

    2011-10-01

    Interspecific hybridization is a significant evolutionary force as well as a powerful method for crop breeding. Partial substitution of the AA subgenome in Brassica napus (A(n) A(n) C(n) C(n) ) with the Brassica rapa (A(r) A(r) ) genome by two rounds of interspecific hybridization resulted in a new introgressed type of B. napus (A(r) A(r) C(n) C(n) ). In this study, we construct a population of recombinant inbred lines of the new introgressed type of B. napus. Microsatellite, intron-based and retrotransposon markers were used to characterize this experimental population with genetic mapping, genetic map comparison and specific marker cloning analysis. Yield-related traits were also recorded for identification of quantitative trait loci (QTLs). A remarkable range of novel genomic alterations was observed in the population, including simple sequence repeat (SSR) mutations, chromosomal rearrangements and retrotransposon activations. Most of these changes occurred immediately after interspecific hybridization, in the early stages of genome stabilization and derivation of experimental lines. These novel genomic alterations affected yield-related traits in the introgressed B. napus to an even greater extent than the alleles alone that were introgressed from the A(r) subgenome of B. rapa, suggesting that genomic changes induced by interspecific hybridization are highly significant in both genome evolution and crop improvement. © 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd.

  12. Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring

    Directory of Open Access Journals (Sweden)

    Luft Karina

    2010-03-01

    Full Text Available Abstract Background High-throughput cultivations in microtiter plates are the method of choice to express proteins from recombinant clone libraries. Such processes typically include several steps, whereby some of them are linked by replication steps: transformation, plating, colony picking, preculture, main culture and induction. In this study, the effects of conventional replication methods and replication tools (8-channel pipette, 96-pin replicators: steel replicator with fixed or spring-loaded pins, plastic replicator with fixed pins on growth kinetics of Escherichia coli SCS1 pQE-30 pSE111 were observed. Growth was monitored with the BioLector, an on-line monitoring technique for microtiter plates. Furthermore, the influence of these effects on product formation of Escherichia coli pRhotHi-2-EcFbFP was investigated. Finally, a high-throughput cultivation process was simulated with Corynebacterium glutamicum pEKEx2-phoD-GFP, beginning at the colony picking step. Results Applying different replication tools and methods for one single strain resulted in high time differences of growth of the slowest and fastest growing culture. The shortest time difference (0.3 h was evaluated for the 96 cultures that were transferred with an 8-channel pipette from a thawed and mixed cryoculture and the longest time difference (6.9 h for cultures that were transferred with a steel replicator with fixed pins from a frozen cryoculture. The on-line monitoring of a simulated high-throughput cultivation process revealed strong variances in growth kinetics and a twofold difference in product formation. Another experiment showed that varying growth kinetics, caused by varying initial biomass concentrations (OD600 of 0.0125 to 0.2 led to strongly varying product formation upon induction at a defined point of time. Conclusions To improve the reproducibility of high-throughput cultivation processes and the comparability between different applied cultures, it is strongly

  13. SU-C-202-03: A Tool for Automatic Calculation of Delivered Dose Variation for Off-Line Adaptive Therapy Using Cone Beam CT

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B; Lee, S; Chen, S; Zhou, J; Prado, K; D’Souza, W; Yi, B [University of Maryland School of Medicine, Baltimore, MD (United States)

    2016-06-15

    Purpose: Monitoring the delivered dose is an important task for the adaptive radiotherapy (ART) and for determining time to re-plan. A software tool which enables automatic delivered dose calculation using cone-beam CT (CBCT) has been developed and tested. Methods: The tool consists of four components: a CBCT Colleting Module (CCM), a Plan Registration Moduel (PRM), a Dose Calculation Module (DCM), and an Evaluation and Action Module (EAM). The CCM is triggered periodically (e.g. every 1:00 AM) to search for newly acquired CBCTs of patients of interest and then export the DICOM files of the images and related registrations defined in ARIA followed by triggering the PRM. The PRM imports the DICOM images and registrations, links the CBCTs to the related treatment plan of the patient in the planning system (RayStation V4.5, RaySearch, Stockholm, Sweden). A pre-determined CT-to-density table is automatically generated for dose calculation. Current version of the DCM uses a rigid registration which regards the treatment isocenter of the CBCT to be the isocenter of the treatment plan. Then it starts the dose calculation automatically. The AEM evaluates the plan using pre-determined plan evaluation parameters: PTV dose-volume metrics and critical organ doses. The tool has been tested for 10 patients. Results: Automatic plans are generated and saved in the order of the treatment dates of the Adaptive Planning module of the RayStation planning system, without any manual intervention. Once the CTV dose deviates more than 3%, both email and page alerts are sent to the physician and the physicist of the patient so that one can look the case closely. Conclusion: The tool is capable to perform automatic dose tracking and to alert clinicians when an action is needed. It is clinically useful for off-line adaptive therapy to catch any gross error. Practical way of determining alarming level for OAR is under development.

  14. Genome-wide detection of loss of heterozygosity and copy number variation in a human lung large cell carcinoma cell line by affymetrix single-nucleotide polymorphism array 500K

    Directory of Open Access Journals (Sweden)

    Bin HU

    2008-06-01

    Full Text Available Background and objective Loss of heterozygosity (LOH and Copy number copy number variation (CNV of DNA sequences is a common feature of cancer genomes, which is thought to be linked to tumorigenesis and progression. High-density single-nucleotide polymorphism (SNP genotyping array are able to provided a genotype and copy number information with genome-wide coverage, which is suitable for the analysis of complex genetic alterations present in cancer. Thus a human lung large cell carcinoma cell line NL9980 was assayed for the global profile of LOH and CNV. Methods Genomic DNA from the cell line was screened for LOH and CNV using Affymetrix GeneChip® Human Mapping array 500K Set. The hybridization intensity data of 500 000 SNP loci was analyzed using Affymetrix proprietary software for genotyping and copy number of each locus, and a genome-wide map of LOH and CNV of the cell line was constructed. Results The SNP call rate of array Nsp I (-262K was 95.14%, and the rate of Sty I (-238K was 97.15%. The both call rates of the components of 500K array set were in excess of 93%, the cardinal quality control standard. LOH profiles of the sample were across all chromosomes, and most of CN gains and losses regions were found on chromosomes such as 2, 3, 4, 5, 7, 10, 11, and 18. Conclusion The results have shown that there were complex genetic alterations present in NL9980. And it is possible to achieve high performance outcomes using Affymetrix SNP array 500K to interrogate LOH and CNV in lung cancer genome. This advance of high-resolution with allelic information should substantially improve the ability to further understanding of the genetic basis of lung cancers.

  15. Analysis of L -shell line spectra with 50-ps time resolution from Mo X -pinch plasmas.

    Science.gov (United States)

    Hansen, S B; Shlyaptseva, A S; Pikuz, S A; Shelkovenko, T A; Sinars, D B; Chandler, K M; Hammer, D A

    2004-08-01

    Mo wire X pinches typically emit several x-ray bursts from a bright spot near the crossing of the X -pinch wires. Streak camera images of L -shell line emission from Mo wire X pinches have been analyzed using a non-local thermodynamic equilibrium (NLTE) collisional-radiative atomic kinetics model, providing temperature and density profiles with approximately 50 ps time resolution over the approximately 350 ps x-ray bursts. In conjunction with nonspectroscopic measurements, the analysis is used to propose a picture of the dynamic evolution of the X -pinch plasma. The L -shell spectra from the first x-ray burst indicate an electron density near 10(22) cm(-3) and an electron temperature near 1 keV; subsequent x-ray bursts have L -shell spectra that indicate electron temperatures slightly above 1 keV and electron densities near 10(20) and 10(21) cm(-3). The size of the L -shell line-emitting region is estimated to be near 10 microm for the first x-ray burst and much larger for the later bursts. It is proposed that inner-shell excitation of low ionization stages of Mo in a microm -scale plasma region contributes to the observed radiation from the first micropinch, which typically emits a short burst of >3 keV radiation and has L -shell spectra characterized by broad spectral lines overlaying an intense continuum.

  16. δ18O and δD variations in some volcanic lakes on the Cameroon Volcanic Line (West-Africa: generating isotopic baseline data for volcano monitoring and surveillance in Cameroon

    Directory of Open Access Journals (Sweden)

    . Issa

    2014-06-01

    Full Text Available Based on geo-anthropological and geochemical studies, catastrophes similar to the unprecedented gas explosions in the mid-1980s from the Cameroonian killer lakes Nyos and Monoun, might occur in any of the 37 other lakes located along the Cameroon Volcanic Line (CVL. Because people could suffer loss and desolation from predictable catastrophes in the future, monitoring/surveillance policies must be established. Due to their location, crater lakes integrate the geochemical processes that develop in the Earth’s crust due to magmatic activities. Therefore, monitoring the surface manifestations of those deep seated and/or hydrothermal processes might reveal increases/decreases in magmatic activities. The anomalous changes in a volcanic lake induced by mixing with exogenous fluids that have a specific δ18O and δD compositional fingerprint (magmatic, metamorphic, etc. could be utilized to predict volcanic hazards. If the steady state of a lake environment and the external and intrinsic parameters that control its hydrodynamics are clearly identified and reasonably understood, the anomalous evolutionary processes that compromise its stability can be identified. This study attempts to collect the δ18O and δD data from 17 Cameroonian lakes to help establish a volcano-related monitoring/surveillance network. This work identifies the processes that control the isotopic composition of the lakes and assesses the intra-/inter- and spatial δ18O/δD variations. Almost all of the lakes contain meteoric water. These lakes are mostly isotopically stratified; epilimnia is generally more positive than the hypolimnia. However, although the rainfall is gradually depleted in heavy isotopes when moving from the South to the North due to the latitude effect, the lakes become more enriched (0.6‰/100 km due to evaporation. The evaluated impact of several parameters on the isotopic variation suggests that the hydrological setting may play an important, albeit not

  17. Diurnal variation of mountain waves

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    R. M. Worthington

    2006-11-01

    Full Text Available Mountain waves could be modified as the boundary layer varies between stable and convective. However case studies show mountain waves day and night, and above e.g. convective rolls with precipitation lines over mountains. VHF radar measurements of vertical wind (1990–2006 confirm a seasonal variation of mountain-wave amplitude, yet there is little diurnal variation of amplitude. Mountain-wave azimuth shows possible diurnal variation compared to wind rotation across the boundary layer.

  18. High Line

    DEFF Research Database (Denmark)

    Kiib, Hans

    2015-01-01

    factories and warehouses on Gansevoort Street. Today the High Line is a beautiful park covered with new tiles, viewing platforms and smaller recreational areas. The park bridge has simple, uniform, urban fittings and features a variety of flowering plants, grasses, shrubs and trees from around the world......, and galleries. With the High Line, a new urban architectural typology has been created that is aesthetically enriching and sets new standards for urban transformation and urban life. “The park accommodates the wild, the cultivated, the intimate and the social. Access points are durational experiences designed...

  19. Experiencing variation

    DEFF Research Database (Denmark)

    Kobayashi, Sofie; Berge, Maria; Grout, Brian William Wilson

    2017-01-01

    This study contributes towards a better understanding of learning dynamics in doctoral supervision by analysing how learning opportunities are created in the interaction between supervisors and PhD students, using the notion of experiencing variation as a key to learning. Empirically, we have bas...... were discussed, created more complex patterns of variation. Both PhD students and supervisors can learn from this. Understanding of this mechanism that creates learning opportunities can help supervisors develop their competences in supervisory pedagogy....

  20. Genetic variation and population structure of maize inbred lines adapted to the mid-altitude sub-humid maize agro-ecology of Ethiopia using single nucleotide polymorphic (SNP) markers.

    Science.gov (United States)

    Ertiro, Berhanu Tadesse; Semagn, Kassa; Das, Biswanath; Olsen, Michael; Labuschagne, Maryke; Worku, Mosisa; Wegary, Dagne; Azmach, Girum; Ogugo, Veronica; Keno, Tolera; Abebe, Beyene; Chibsa, Temesgen; Menkir, Abebe

    2017-10-12

    Molecular characterization is important for efficient utilization of germplasm and development of improved varieties. In the present study, we investigated the genetic purity, relatedness and population structure of 265 maize inbred lines from the Ethiopian Institute of Agricultural Research (EIAR), the International Maize and Wheat Improvement Centre (CIMMYT) and the International Institute of Tropical Agriculture (IITA) using 220,878 single nucleotide polymorphic (SNP) markers obtained using genotyping by sequencing (GBS). Only 22% of the inbred lines were considered pure with population structure analysis consistently suggested the presence of three groups, which generally agreed with pedigree information (genetic background). Although not distinct enough, the SNP markers showed some level of separation between the two CIMMYT heterotic groups A and B established based on pedigree and combining ability information. The high level of heterogeneity detected in most of the inbred lines suggested the requirement for purification or further inbreeding except those deliberately maintained at early inbreeding level. The genetic distance and relative kinship analysis clearly indicated the uniqueness of most of the inbred lines in the maize germplasm available for breeders in the mid-altitude maize breeding program of Ethiopia. Results from the present study facilitate the maize breeding work in Ethiopia and germplasm exchange among breeding programs in Africa. We suggest the incorporation of high density molecular marker information in future heterotic group assignments.

  1. Variational analysis

    CERN Document Server

    Rockafellar, R Tyrrell

    1998-01-01

    From its origins in the minimization of integral functionals, the notion of 'variations' has evolved greatly in connection with applications in optimization, equilibrium, and control. It refers not only to constrained movement away from a point, but also to modes of perturbation and approximation that are best describable by 'set convergence', variational convergence of functions and the like. This book develops a unified framework and, in finite dimension, provides a detailed exposition of variational geometry and subdifferential calculus in their current forms beyond classical and convex analysis. Also covered are set-convergence, set-valued mappings, epi-convergence, duality, maximal monotone mappings, second-order subderivatives, measurable selections and normal integrands. The changes in this 3rd printing mainly concern various typographical corrections, and reference omissions that came to light in the previous printings. Many of these reached the authors' notice through their own re-reading, that of th...

  2. Variational principles

    CERN Document Server

    Moiseiwitsch, B L

    2004-01-01

    This graduate-level text's primary objective is to demonstrate the expression of the equations of the various branches of mathematical physics in the succinct and elegant form of variational principles (and thereby illuminate their interrelationship). Its related intentions are to show how variational principles may be employed to determine the discrete eigenvalues for stationary state problems and to illustrate how to find the values of quantities (such as the phase shifts) that arise in the theory of scattering. Chapter-by-chapter treatment consists of analytical dynamics; optics, wave mecha

  3. production lines

    Directory of Open Access Journals (Sweden)

    Jingshan Li

    2000-01-01

    Full Text Available In this work, serial production lines with finished goods buffers operating in the pull regime are considered. The machines are assumed to obey Bernoulli reliability model. The problem of satisfying customers demand is addressed. The level of demand satisfaction is quantified by the due-time performance (DTP, which is defined as the probability to ship to the customer a required number of parts during a fixed time interval. Within this scenario, the definitions of DTP bottlenecks are introduced and a method for their identification is developed.

  4. Parallel Lines

    Directory of Open Access Journals (Sweden)

    James G. Worner

    2017-05-01

    Full Text Available James Worner is an Australian-based writer and scholar currently pursuing a PhD at the University of Technology Sydney. His research seeks to expose masculinities lost in the shadow of Australia’s Anzac hegemony while exploring new opportunities for contemporary historiography. He is the recipient of the Doctoral Scholarship in Historical Consciousness at the university’s Australian Centre of Public History and will be hosted by the University of Bologna during 2017 on a doctoral research writing scholarship.   ‘Parallel Lines’ is one of a collection of stories, The Shapes of Us, exploring liminal spaces of modern life: class, gender, sexuality, race, religion and education. It looks at lives, like lines, that do not meet but which travel in proximity, simultaneously attracted and repelled. James’ short stories have been published in various journals and anthologies.

  5. Variation in concentrations of high-molecular-weight glutenin subunits and macropolymers in wheat grains of a recombinant inbred lines population and in two contrasting eco-sites in China

    DEFF Research Database (Denmark)

    Li, Xiangnan; Cai, Jian; Liu, Fulai

    2012-01-01

    BACKGROUND: Concentrations of high-molecular-weight glutenin subunits andmacropolymers in wheat grains are important indicators of grain quality, which are genetically determined and affected by environmental factors. The 6 VS·6AL translocation chromosome segment is reported to own high powdery m...... wheat cultivars for high resistence to powdery mildew and yellow rust with less risk of undesirable effects on grain quality. c 2012 Society of Chemical Industry Supporting information may be found in the online version of this article.......BACKGROUND: Concentrations of high-molecular-weight glutenin subunits andmacropolymers in wheat grains are important indicators of grain quality, which are genetically determined and affected by environmental factors. The 6 VS·6AL translocation chromosome segment is reported to own high powdery...... mildew and yellow rust resistance genes of Pm21 and Yr26. This study investigated the variation in concentrations of high-molecular-weight glutenin subunits (HMW-GS) and gluteninmacropolymer (GMP) in response to the 6 VS·6AL translocation segment and the two contrasting sites. RESULTS: Large variations...

  6. Non-LTE aluminium abundances in late-type stars

    Science.gov (United States)

    Nordlander, T.; Lind, K.

    2017-11-01

    Aims: Aluminium plays a key role in studies of the chemical enrichment of the Galaxy and of globular clusters. However, strong deviations from LTE (non-LTE) are known to significantly affect the inferred abundances in giant and metal-poor stars. Methods: We present non-local thermodynamic equilibrium (NLTE) modeling of aluminium using recent and accurate atomic data, in particular utilizing new transition rates for collisions with hydrogen atoms, without the need for any astrophysically calibrated parameters. For the first time, we perform 3D NLTE modeling of aluminium lines in the solar spectrum. We also compute and make available extensive grids of abundance corrections for lines in the optical and near-infrared using one-dimensional model atmospheres, and apply grids of precomputed departure coefficients to direct line synthesis for a set of benchmark stars with accurately known stellar parameters. Results: Our 3D NLTE modeling of the solar spectrum reproduces observed center-to-limb variations in the solar spectrum of the 7835 Å line as well as the mid-infrared photospheric emission line at 12.33 μm. We infer a 3D NLTE solar photospheric abundance of A(Al) = 6.43 ± 0.03, in exact agreement with the meteoritic abundance. We find that abundance corrections vary rapidly with stellar parameters; for the 3961 Å resonance line, corrections are positive and may be as large as +1 dex, while corrections for subordinate lines generally have positive sign for warm stars but negative for cool stars. Our modeling reproduces the observed line profiles of benchmark K-giants, and we find abundance corrections as large as -0.3 dex for Arcturus. Our analyses of four metal-poor benchmark stars yield consistent abundances between the 3961 Å resonance line and lines in the UV, optical and near-infrared regions. Finally, we discuss implications for the galactic chemical evolution of aluminium.

  7. VT Digital Line Graph Miscellaneous Transmission Lines

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of Miscellaineous Transmission Lines. Digital line graph (DLG) data are digital representations of cartographic...

  8. Emission-Line Region Variability

    Science.gov (United States)

    Peterson, Bradley M.

    We propose to obtain simultaneous optical and ultraviolet observations of the rapidly varying active galaxies Akn 120 and 3C 120. Both these sources are distinguished by short-time scale variations in their continuum and broadline fluxes, and we intend to exploit this property to determine fundamental characteristics of the emission-line gas. Akn 120 has been studied extensively by the Ohio State group, and is one of the few active galaxies for which a reliable upper limit for the separation between the continuum source and the emission-line clouds has been established from reverberation measurements. The important goals of the proposed project are (1) to provide a suitable database of optical and ultraviolet broad-line flux measurements obtained during different continuum states and (2) to compare the temporal behavior of optical and ultraviolet emission lines. In particular, we wish to determine whether or not C III] A1909 varies on the same time scale as the Balmer lines and how much of the flux in this feature can actually be ascribed to broad-line emission from C^+2. These data will enable us to make a differential comparison with predictions of photoionization models, since the emission-line spectrum will change in response to the variable ionizing continuum flux. Such a differential comparison between observation and theory should be more reliable than attempts to match absolute intensities because errors in the atomic data base should tend to cancel out.

  9. Brand Equity and Vertical Product Line Extent

    OpenAIRE

    Taylor Randall; Karl Ulrich; David Reibstein

    1998-01-01

    This paper addresses the question of how the vertical structure of a product line relates to brand equity. Does the presence of “premium” or high-quality products in a product line enhance brand equity? Conversely, does the presence of “economy” or low-quality products in a product line diminish brand equity? Economists and marketing researchers refer to variation in quality levels of products within a category as “vertical” differentiation, whereas variation in the function or “category” of ...

  10. Epigenetic variation during the adult lifespan

    DEFF Research Database (Denmark)

    Talens, Rudolf P; Christensen, Kaare; Putter, Hein

    2012-01-01

    spectrometry, we investigated variation in global (LINE1) DNA methylation and in DNA methylation at INS, KCNQ1OT1, IGF2, GNASAS, ABCA1, LEP, and CRH, candidate loci for common diseases. Except for KCNQ1OT1, interindividual variation in locus-specific DNA methylation was larger in old individuals than in young...

  11. Genetic variation in pea seed globulin composition

    NARCIS (Netherlands)

    Tzitzikas, E.; Vincken, J.P.; Groot, de J.; Gruppen, H.; Visser, R.G.F.

    2006-01-01

    A quantitative characterization of seeds from 59 pea (Pisum sativum L.) lines and relative taxa with various external characteristics and wide geographical origin was performed to explore the genetic variation of pea concerning its starch and protein contents and globulin composition. Pea lines,

  12. Rigidly connected magnetic lines: twisting and winding of magnetic lines

    Science.gov (United States)

    Prasad, G.

    2017-10-01

    The dynamical process of magnetic flux variation in a fluid's stream tube is described by constructing 1+1+ (2) decomposition of the gradient of fluid's 4-velocity. The necessary and sufficient conditions are obtained for a spacelike congruence to be a congruence of rigidly connected spacelike curves. The evolution of magnetic flux in a magnetic tube is explored under the assumptions that magnetic lines are rigidly connected and the chemical potential of the fluid is constant along a magnetic tube. The interplay between magnetic and stream tubes is demonstrated. It is shown that the growth of magnetic energy in a magnetic tube cannot exceed to that of a stream tube. It is found that the proper time variation of twist of magnetic lines is caused by gravitation inside a neutron star if magnetic lines are rigidly connected and charge neutrality condition holds. Helmholtz-like magnetic vorticity flux conservation in a magnetic tube constituted by rigidly connected geodetic magnetic lines is derived under the assumption that the charge neutrality condition holds. It is shown that the winding of frozen-in poloidal magnetic field due to differential rotation requires meridional circulation in an axisymmetric stationary hydromagnetic configuration.

  13. The Emission Line Objects At 0PEARS

    Science.gov (United States)

    Pirzkal, Norbert; Malhotra, S.; Rhoads, J. J. E.; Ly, C.; Rothberg, B.; Dahlen, T.

    2012-05-01

    Emission line galaxies are a powerful tracer of star formation in the Universe. By computing and examining the shape of the line luminosity function (the number density per logarithmic interval in line luminosity) we can study how star formation occurred in star forming galaxies. We can also look for variation in the line luminosity function of these objects as a function of redshift to look for evidence of evolution in the way star formation took place over the last few billion years. We present emission line luminosity functions obtained using the slitless grism survey data of the PEARS projects. We applied the PEARS-2D technique to pinpoint the location of line emission in field galaxies and hence were able to extract spectra of individual line emission regions in the PEARS fields, which covers a large fraction of the GOODS-N and GOODS-S fields. We detected lines with fluxes as low as 5. 10^-18 erg/s/cm^2 and identified Ha, OIII, OII, Hg and Lya lines, over a redshift range of 0lines we identified are Ha (213 lines, 0lines, 0.2lines, 0.6line emission regions, multiple line emissions regions as well as several cases of multiple star forming regions in single galaxies. We present the luminosity functions for Ha, OII, and OIII computed across these relatively broad redshift ranges using both the Vmax and STY methods and investigate the redshift dependence of these luminosity functions, and the physical distribution of the emission line regions we detect.

  14. Peripheral intravenous line - infants

    Science.gov (United States)

    PIV - infants; Peripheral IV - infants; Peripheral line - infants; Peripheral line - neonatal ... A peripheral intravenous line (PIV) is a small, short, plastic tube, called a catheter. A health care provider puts the PIV through the ...

  15. Sewer Main Pipe Lines

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is a line feature dataset with lines across the island of Guam. These lines represent the sewer mains that carry refuse to the sewer plants for processing and...

  16. Extensive Variation in Chromatin States Across Humans

    KAUST Repository

    Kasowski, M.

    2013-10-17

    The majority of disease-associated variants lie outside protein-coding regions, suggesting a link between variation in regulatory regions and disease predisposition. We studied differences in chromatin states using five histone modifications, cohesin, and CTCF in lymphoblastoid lines from 19 individuals of diverse ancestry. We found extensive signal variation in regulatory regions, which often switch between active and repressed states across individuals. Enhancer activity is particularly diverse among individuals, whereas gene expression remains relatively stable. Chromatin variability shows genetic inheritance in trios, correlates with genetic variation and population divergence, and is associated with disruptions of transcription factor binding motifs. Overall, our results provide insights into chromatin variation among humans.

  17. Line Transport in Turbulent Atmospheres

    Science.gov (United States)

    Nikoghossian, A. G.

    2017-07-01

    The spectral line transfer in turbulent atmospheres with a spatially correlated velocity field is examined. Both the finite and semi-infinite media are treated. In finding the observed intensities we first deal with the problem for determining the mean intensity of radiation emerging from the medium for a fixed value of turbulent velocity at its boundary. A new approach proposed for solving this problem is based on the invariant imbedding technique which yields the solution of the proper problems for a family of media of different optical thicknesses and allows tackling different kinds of inhomogeneous problems. The dependence of the line profile, integral intensity, and the line width on the mean correlation length and the average value of the hydrodynamic velocity is studied. It is shown that the transition from a micro-turbulent regime to a macro-turbulence occurs within a comparatively narrow range of variation in the correlation length . Ambartsumian's principle of invariance is used to solve the problem of diffuse reflection of the line radiation from a one-dimensional semi-infinite turbulent atmosphere. In addition to the observed spectral line profile, statistical averages describing the diffusion process in the atmosphere (mean number of scattering events, average time spent by a diffusing photon in the medium) are determined. The dependence of these quantities on the average hydrodynamic velocity and correlation coefficient is studied.

  18. Periodic Variations in the Coronal Green Line Intensity and their ...

    Indian Academy of Sciences (India)

    tribpo

    The last one contains all records that did not belong to the former two groups. These data were not taken into an account in the following studies. To obtain corresponding. WLC structures, the qualitative Mk3 image data were processed using digital unsharp masking. Resulting shapes of the WLC structures situated in the ...

  19. Abstract Line Designs

    Science.gov (United States)

    Nevinskas, Nancy

    2011-01-01

    In this article, the author describes a unit on the exploration of line. The unit was composed of two individual line lessons. In the first lesson, students were introduced to line as an element of design. They were asked to describe different types of lines, and look for them in art reproductions. The second lesson in the unit involved painting…

  20. Community LINE Source Model (C-LINE)

    Science.gov (United States)

    This presentation provides an introduction for the live demo and explains the purpose of C-LINE and its key features. C-LINE is a web-based model designed to inform the community user of local air quality impacts due to mobile-sources in their region of interest using a simplifie...

  1. Nuclear reactor overflow line

    Science.gov (United States)

    Severson, Wayne J.

    1976-01-01

    The overflow line for the reactor vessel of a liquid-metal-cooled nuclear reactor includes means for establishing and maintaining a continuous bleed flow of coolant amounting to 5 to 10% of the total coolant flow through the overflow line to prevent thermal shock to the overflow line when the reactor is restarted following a trip. Preferably a tube is disposed concentrically just inside the overflow line extending from a point just inside the reactor vessel to an overflow tank and a suction line is provided opening into the body of liquid metal in the reactor vessel and into the annulus between the overflow line and the inner tube.

  2. Finite-Size and Solvent Dependent Line Tension Effects for Nanoparticles at the Air-Liquid Surface.

    Science.gov (United States)

    Matsubara, Hiroki; Otsuka, Jo; Law, Bruce M

    2018-01-09

    The line tension for a nanoparticle (NP) at the air-liquid surface can be determined by examining the variation in NP solution surface tension with bulk NP concentration. In this publication the variation in line tension with liquid solvent is examined for the homologous series of liquids from n-decane through to n-octadecane. Finite-size line tension effects are also studied by examining the variation in line tension with NP size for NPs at the air-octadecane surface. Both the line tension variation with solvent and NP size can be qualitatively explained using an interface displacement model for the line tension.

  3. VT Electric Transmission Line Corridors - corridor lines

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The ELTRN layer depicts electric transmission line corridors in Vermont. Various methods have been used to digitize features. The data layer...

  4. Lined canvas paintings

    DEFF Research Database (Denmark)

    Krarup Andersen, Cecil

    2013-01-01

    This work evaluates the lining history of the Danish Golden Age collection of canvas paintings from the nineteenths century at SMK, The National Gallery of Denmark, and seeks to understand the moisture sensitivity of the paintings before and after lining. This is done by chemical analysis...... and tensile testing samples from the tacking edges as well as lined mock-up samples. The ability of the different lining techniques to support canvas paintings is evaluated in terms of their initial stretching and during fluctuations of relative humidity. Six different combinations of lining adhesives...... and textiles were examined. These included the adhesives Beva 371, Plextol D360, wax-resin, and glue-paste. The lining textiles were linen and polyester sailcloth. A naturally aged canvas painting and a modern painting were lined using these materials and methods. Testing of the lined paintings included uni...

  5. Peripheral arterial line (image)

    Science.gov (United States)

    A peripheral arterial line is a small, short plastic catheter placed through the skin into an artery of the arm or leg. The purpose of a peripheral arterial line is to allow continuous monitoring of blood pressure ...

  6. Variations on a theme of Grothendieck

    DEFF Research Database (Denmark)

    Martens, Johan; Thaddeus, Michael

    variations on this theme, we prove corresponding results for principal bundles over the following schemes and stacks: (1) a line modulo the group of nth roots of unity; (2) a football, that is, an orbifold of genus zero with two marked points; (3) a gerbe over a football whose structure group is the nth...... roots of unity; (4) a line modulo an action of a split torus; (5) a chain of lines meeting in nodes; and (6) a chain modulo an action of a split torus. We also prove that the automorphism groups of such bundles are smooth, affine, and connected....

  7. Homotopic Polygonal Line Simplification

    DEFF Research Database (Denmark)

    Deleuran, Lasse Kosetski

    This thesis presents three contributions to the area of polygonal line simplification, or simply line simplification. A polygonal path, or simply a path is a list of points with line segments between the points. A path can be simplified by morphing it in order to minimize some objective function...

  8. Intrapopulation genome size variation in D. melanogaster reflects life history variation and plasticity.

    Directory of Open Access Journals (Sweden)

    Lisa L Ellis

    2014-07-01

    Full Text Available We determined female genome sizes using flow cytometry for 211 Drosophila melanogaster sequenced inbred strains from the Drosophila Genetic Reference Panel, and found significant conspecific and intrapopulation variation in genome size. We also compared several life history traits for 25 lines with large and 25 lines with small genomes in three thermal environments, and found that genome size as well as genome size by temperature interactions significantly correlated with survival to pupation and adulthood, time to pupation, female pupal mass, and female eclosion rates. Genome size accounted for up to 23% of the variation in developmental phenotypes, but the contribution of genome size to variation in life history traits was plastic and varied according to the thermal environment. Expression data implicate differences in metabolism that correspond to genome size variation. These results indicate that significant genome size variation exists within D. melanogaster and this variation may impact the evolutionary ecology of the species. Genome size variation accounts for a significant portion of life history variation in an environmentally dependent manner, suggesting that potential fitness effects associated with genome size variation also depend on environmental conditions.

  9. Intrapopulation Genome Size Variation in D. melanogaster Reflects Life History Variation and Plasticity

    Science.gov (United States)

    Ellis, Lisa L.; Huang, Wen; Quinn, Andrew M.; Ahuja, Astha; Alfrejd, Ben; Gomez, Francisco E.; Hjelmen, Carl E.; Moore, Kristi L.; Mackay, Trudy F. C.; Johnston, J. Spencer; Tarone, Aaron M.

    2014-01-01

    We determined female genome sizes using flow cytometry for 211 Drosophila melanogaster sequenced inbred strains from the Drosophila Genetic Reference Panel, and found significant conspecific and intrapopulation variation in genome size. We also compared several life history traits for 25 lines with large and 25 lines with small genomes in three thermal environments, and found that genome size as well as genome size by temperature interactions significantly correlated with survival to pupation and adulthood, time to pupation, female pupal mass, and female eclosion rates. Genome size accounted for up to 23% of the variation in developmental phenotypes, but the contribution of genome size to variation in life history traits was plastic and varied according to the thermal environment. Expression data implicate differences in metabolism that correspond to genome size variation. These results indicate that significant genome size variation exists within D. melanogaster and this variation may impact the evolutionary ecology of the species. Genome size variation accounts for a significant portion of life history variation in an environmentally dependent manner, suggesting that potential fitness effects associated with genome size variation also depend on environmental conditions. PMID:25057905

  10. Model to Design Drip Hose Lateral Line

    Science.gov (United States)

    Ludwig, Rafael; Cury Saad, João Carlos

    2014-05-01

    Introduction The design criterion for non-pressure compensating drip hose is normally to have 10% of flow variation (Δq) in the lateral line, corresponding to 20% of head pressure variation (ΔH). Longer lateral lines in drip irrigation systems using conventional drippers provide cost reduction, but it is necessary to obtain to the uniformity of irrigation [1]. The use of Δq higher levels can provide longer lateral lines. [4] proposes the use of a 30% Δq and he found that this value resulted in distribution uniformity over 80%. [1] considered it is possible to extend the lateral line length using two emitters spacing in different section. He assumed that the spacing changing point would be at 40% of the total length, because this is approximately the location of the average flow according with [2]. [3] found that, for practical purposes, the average pressure is located at 40% of the length of the lateral line and that until this point it has already consumed 75% of total pressure head loss (hf ). In this case, the challenge for designers is getting longer lateral lines with high values of uniformity. Objective The objective of this study was to develop a model to design longer lateral lines using non-pressure compensating drip hose. Using the developed model, the hypotheses to be evaluated were: a) the use of two different spacing between emitters in the same lateral line allows longer length; b) it is possible to get longer lateral lines using high values of pressure variation in the lateral lines since the distribution uniformity stays below allowable limits. Methodology A computer program was developed in Delphi® based on the model developed and it is able to design lateral lines in level using non-pressure compensating drip hose. The input data are: desired distribution uniformity (DU); initial and final pressure in the lateral line; coefficients of relationship between emitter discharge and pressure head; hose internal diameter; pipe cross-sectional area

  11. Evaluation of Lentil Recombinant Inbred Lines using Drought Tolerance Indices

    Directory of Open Access Journals (Sweden)

    Mohammad Hassan Rahimi

    2017-04-01

    Full Text Available To identify drought tolerant lines among 168 recombinant inbred lines derived from a cross between Hindi variety of L3685 (high yielding, erect type and early growth as female parent and Iranian variety of Qazvin (with prostrate growth and late growth as male parent, two experiments were conducted in randomized complete block design with three replications under non-stress and drought stress conditions at the experimental Field of Shahrekord University in 2013. Results of combined analysis of variance showed that there were significant differences among lines under study in both experimental conditions in terms of grain yield (P≤0.01. Significant interaction of line×conditions revealed that lines responded differently to drought stress based on grain yield. Results also indicates that lines 160, 125 and 129 were promising lines under both conditions in terms of grain yield. Positive and significant correlation between tolerance indices and grain yield under stress and non-stress conditions indicated that the STI, MP, HARM and GMP indices may identify promising from non promising lines. Based on the above criteria, lines 160, 125, 48, 103 and 129 were recognized as drought tolerant lines. According to the results of principal components analysis, the first and second components determined 97.8% of the total variations among genotypes under study for drought resistance indices. The distribution of lines in the biplot showed genetic variations to the drought stress and thus lines 160, 125, 48, 129 and 103 were identified as high yielders under drought stress condition.

  12. Magnetic Field - Secular Variation of the Declination Component for the Epoch 2010.0 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer shows isoporic lines (lines of equal annual change, or secular variation, in the declination of the Earth's magnetic field), derived from the...

  13. Transmission line fault distance and direction estimation using ...

    African Journals Online (AJOL)

    An accurate fault distance and direction estimation based on application of artificial neural networks for protection of doubly fed transmission lines is presented in this paper. The proposed method uses the voltage and current available at only the local end of line. This method is adaptive to the variation of fault location, fault ...

  14. Susceptibility testing of fish cell lines for virus isolation

    DEFF Research Database (Denmark)

    Ariel, Ellen; Skall, Helle Frank; Olesen, Niels Jørgen

    2009-01-01

    compare susceptibility between cell lines and between lineages within a laboratory and between laboratories (Inter-laboratory Proficiency Test). The objective being that the most sensitive cell line and lineages are routinely selected for diagnostic purposes.In comparing cell lines, we simulated "non......-cell-culture-adapted" virus by propagating the virus in heterologous cell lines to the one tested. A stock of test virus was produced and stored at - 80 °C and tests were conducted biannually. This procedure becomes complicated when several cell lines are in use and does not account for variation among lineages. In comparing...... cell lineages, we increased the number of isolates of each virus, propagated stocks in a given cell line and tested all lineages of that line in use in the laboratory. Testing of relative cell line susceptibility between laboratories is carried out annually via the Inter-laboratory Proficiency Test...

  15. Bilateral renal artery variation

    OpenAIRE

    Üçerler, Hülya; Üzüm, Yusuf; İkiz, Z. Aslı Aktan

    2015-01-01

    Each kidney is supplied by a single renal artery, although renal artery variations are common. Variations of the renal arteryhave become important with the increasing number of renal transplantations. Numerous studies describe variations in renalartery anatomy. Especially the left renal artery is among the most critical arterial variations, because it is the referred side forresecting the donor kidney. During routine dissection in a formalin fixed male cadaver, we have found a bilateral renal...

  16. Series Transmission Line Transformer

    Science.gov (United States)

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  17. Studying Variation in Tunes

    NARCIS (Netherlands)

    Janssen, B.; van Kranenburg, P.

    2014-01-01

    Variation in music can be caused by different phenomena: conscious, creative manipulation of musical ideas; but also unconscious variation during music recall. It is the latter phenomenon that we wish to study: variation which occurs in oral transmission, in which a melody is taught without the help

  18. Function of lateral line canal morphology.

    Science.gov (United States)

    Klein, Adrian; Bleckmann, Horst

    2015-01-01

    Fish perceive water motions and pressure gradients with their lateral line. Lateral line information is used for prey detection, spatial orientation, predator avoidance, schooling behavior, intraspecific communication and station holding. The lateral line of most fishes consists of superficial neuromasts (SNs) and canal neuromasts (CNs). The distribution of SNs and CNs shows a high degree of variation among fishes. Researchers have speculated for decades about the functional significance of this diversity, often without any conclusive answers. Klein et al. (2013) examined how tubules, pore number and pore patterns affect the filter properties of lateral line canals in a marine teleost, the black prickleback (Xiphister atropurpureus). A preliminary mathematical model was formulated and biomimetic sensors were built. For the present study the mathematical model was extended to understand the major underlying principle of how canal dimensions influence the filter properties of the lateral line. Both the extended mathematical model and the sensor experiments show that the number and distribution of pores determine the spatial filter properties of the lateral line. In an environment with little hydrodynamic noise, simple and complex lateral line canals have comparable response properties. However, if exposed to highly turbulent conditions, canals with numerous widely spaced pores increase the signal to noise ratio significantly. © 2014 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

  19. EVIDENCE FOR PHOTOIONIZATION-DRIVEN BROAD ABSORPTION LINE VARIABILITY

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Tinggui; Yang, Chenwei; Wang, Huiyuan [CAS Key Laboratory for Research in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Hefei, Anhui 230026 (China); Ferland, Gary, E-mail: twang@ustc.edu.cn [Department of Physics and Astronomy, University of Kentucky, Lexington, KY 40506 (United States)

    2015-12-01

    We present a qualitative analysis of the variability of quasar broad absorption lines using the large multi-epoch spectroscopic data set of the Sloan Digital Sky Survey Data Release 10. We confirm that variations of absorption lines are highly coordinated among different components of the same ion or the same absorption component of different ions for C iv, Si iv, and N v. Furthermore, we show that the equivalent widths (EWs) of the lines decrease or increase statistically when the continuum brightens or dims. This is further supported by the synchronized variations of emission and absorption-line EWs when the well-established intrinsic Baldwin effect for emission lines is taken into account. We find that the emergence of an absorption component is usually accompanied by the dimming of the continuum while the disappearance of an absorption-line component is accompanied by the brightening of the continuum. This suggests that the emergence or disappearance of a C iv absorption component is only the extreme case, when the ionic column density is very sensitive to continuum variations or the continuum variability the amplitude is larger. These results support the idea that absorption-line variability is driven mainly by changes in the gas ionization in response to continuum variations, that the line-absorbing gas is highly ionized, and in some extreme cases, too highly ionized to be detected in UV absorption lines. Due to uncertainties in the spectroscopic flux calibration, we cannot quantify the fraction of quasars with asynchronized continuum and absorption-line variations.

  20. Variational integrators for reduced magnetohydrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, Michael, E-mail: michael.kraus@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, Boltzmannstraße 2, 85748 Garching (Germany); Technische Universität München, Zentrum Mathematik, Boltzmannstraße 3, 85748 Garching (Germany); Tassi, Emanuele, E-mail: tassi@cpt.univ-mrs.fr [Aix-Marseille Université, Université de Toulon, CNRS, CPT, UMR 7332, 163 avenue de Luminy, case 907, 13288 cedex 9 Marseille (France); Grasso, Daniela, E-mail: daniela.grasso@infm.polito.it [ISC-CNR and Politecnico di Torino, Dipartimento Energia, C.so Duca degli Abruzzi 24, 10129 Torino (Italy)

    2016-09-15

    Reduced magnetohydrodynamics is a simplified set of magnetohydrodynamics equations with applications to both fusion and astrophysical plasmas, possessing a noncanonical Hamiltonian structure and consequently a number of conserved functionals. We propose a new discretisation strategy for these equations based on a discrete variational principle applied to a formal Lagrangian. The resulting integrator preserves important quantities like the total energy, magnetic helicity and cross helicity exactly (up to machine precision). As the integrator is free of numerical resistivity, spurious reconnection along current sheets is absent in the ideal case. If effects of electron inertia are added, reconnection of magnetic field lines is allowed, although the resulting model still possesses a noncanonical Hamiltonian structure. After reviewing the conservation laws of the model equations, the adopted variational principle with the related conservation laws is described both at the continuous and discrete level. We verify the favourable properties of the variational integrator in particular with respect to the preservation of the invariants of the models under consideration and compare with results from the literature and those of a pseudo-spectral code.

  1. Minnesota County Boundaries - lines

    Data.gov (United States)

    Minnesota Department of Natural Resources — Minnesota county boundaries derived from a combination of 1:24,000 scale PLS lines, 1:100,000 scale TIGER, 1:100,000 scale DLG, and 1:24,000 scale hydrography lines....

  2. Database of emission lines

    Science.gov (United States)

    Binette, L.; Ortiz, P.; Joguet, B.; Rola, C.

    1998-11-01

    A widely accessible data bank (available through Netscape) and consiting of all (or most) of the emission lines reported in the litterature is being built. It will comprise objects as diverse as HII regions, PN, AGN, HHO. One of its use will be to define/refine existing diagnostic emission line diagrams.

  3. Anatomy, medical education, and human ancestral variation.

    Science.gov (United States)

    Strkalj, Goran; Spocter, Muhammad A; Wilkinson, A Tracey

    2011-01-01

    It is argued in this article that the human body both in health and disease cannot be fully understood without adequately accounting for the different levels of human variation. The article focuses on variation due to ancestry, arguing that the inclusion of information pertaining to ancestry in human anatomy teaching materials and courses should be carried out and implemented with care and in line with latest developments in biological anthropology and related sciences. This seems to be of particular importance in the education of health professionals, as recent research suggests that better knowledge of human variation can improve clinical skills. It is also argued that relatively small curricular changes relating to the teaching of human variation can produce significant educational gains. Copyright © 2011 American Association of Anatomists.

  4. Epigenetic variation in plant responses to defence hormones.

    Science.gov (United States)

    Latzel, Vít; Zhang, Yuanye; Karlsson Moritz, Kim; Fischer, Markus; Bossdorf, Oliver

    2012-11-01

    There is currently much speculation about the role of epigenetic variation as a determinant of heritable variation in ecologically important plant traits. However, we still know very little about the phenotypic consequences of epigenetic variation, in particular with regard to more complex traits related to biotic interactions. Here, a test was carried out to determine whether variation in DNA methylation alone can cause heritable variation in plant growth responses to jasmonic acid and salicylic acid, two key hormones involved in induction of plant defences against herbivores and pathogens. In order to be able to ascribe phenotypic differences to epigenetic variation, the hormone responses were studied of epigenetic recombinant inbred lines (epiRILs) of Arabidopsis thaliana - lines that are highly variable at the level of DNA methylation but nearly identical at the level of DNA sequence. Significant heritable variation was found among epiRILs both in the means of phenotypic traits, including growth rate, and in the degree to which these responded to treatment with jasmonic acid and salicylic acid. Moreover, there was a positive epigenetic correlation between the responses of different epiRILs to the two hormones, suggesting that plant responses to herbivore and pathogen attack may have a similar molecular epigenetic basis. This study demonstrates that epigenetic variation alone can cause heritable variation in, and thus potentially microevolution of, plant responses to defence hormones. This suggests that part of the variation of plant defences observed in natural populations may be due to underlying epigenetic, rather than entirely genetic, variation.

  5. Glue-paste linings

    DEFF Research Database (Denmark)

    Fuster-López, Laura; Andersen, Cecil Krarup; Bouillon, Nicolas

    2017-01-01

    Glue-paste linings of (Western) canvas paintings have been performed with a variety of materials throughout history and are present in a very significant amount of artworks in collections in Europe and elsewhere. Cereal flours and animal glues were usually the main ingredients because they were...... processes of lined canvas paintings. The impact of cyclic relative humidity on the biological and physical stability of the laminate structure is reported. Carefully constructed mock-ups, simulating lined canvas paintings, were used to examine the effect of pest infestation, mould growth, mechanical damage...

  6. Transnationaliseringen af Maersk Line

    DEFF Research Database (Denmark)

    Sornn-Friese, Henrik

    2017-01-01

    Maersk Line er verdens førende containerrederi og blandt de mest betydningsfulde virksomheder i Danmark. Den globale førerposition blev opnået på relativt kort tid og var et resultat af rederiets beslutning i 1973 om at gå helhjertet ind i containerskibsfarten. Beslutningen blev startskuddet til...... Maersk Lines dybe internationalisering, hvor rederiet ændrede sig fra at være en overvejende danske virksomhed, der betjente internationale markeder, til at være en genuin transnational virksomhed. Med fokus på opbygningen af Maersk Lines globale organisation og særligt etableringen af egne kontorer i...

  7. Wood pole overhead lines

    CERN Document Server

    Wareing, Brian

    2005-01-01

    This new book concentrates on the mechanical aspects of distribution wood pole lines, including live line working, environmental influences, climate change and international standards. Other topics include statutory requirements, safety, profiling, traditional and probabilistic design, weather loads, bare and covered conductors, different types of overhead systems, conductor choice, construction and maintenance. A section has also been devoted to the topic of lightning, which is one of the major sources of faults on overhead lines. The book focuses on the effects of this problem and the strate

  8. Veterans Crisis Line

    Data.gov (United States)

    Department of Veterans Affairs — The caring responders at the Veterans Crisis Line are specially trained and experienced in helping Veterans of all ages and circumstances. Some of the responders are...

  9. MODIFIED METHOD OF LINES

    Directory of Open Access Journals (Sweden)

    Stankevich Anatoliy Nikolaevich

    2016-08-01

    Full Text Available The main idea of the method of solving multidimensional boundary problems is reduction of initial differential equations in partial derivatives to the system of ordinary differential equations. One-dimensional resolving equations allow extending the potential of the method of lines. Although efficient and highly-precise numerical methods have been developed for solution of one-dimensional and initial-boundary value problems their use is impossible in the method of lines. The author considers a new method of lines which is used in order to reduce the dimensionality of multidimensional problems of structural mechanics. The method is used for calculation of thick plates, plates of variable thickness, heterogeneous and multilayered plates. It is proposed to replace finite-difference relations by projection relations which will extend the potential of the method of lines and will allow using the method in the dynamic problems.

  10. Kansas Electric Transmission Lines

    Data.gov (United States)

    Kansas Data Access and Support Center — This data set is a digital representation of the EletcircTransmission lines for the State of Kansas as maintained by the Kansas Corporation Commission. Data is...

  11. Electric Power Transmission Lines

    Data.gov (United States)

    Department of Homeland Security — Transmission Lines are the system of structures, wires, insulators and associated hardware that carry electric energy from one point to another in an electric power...

  12. Superconducting metamaterial transmission line

    Science.gov (United States)

    Rouxinol, Francisco; Wang, Haozhi; Plourde, B. L. T.

    2014-03-01

    Left-handed metamaterials are artificial composite structures with unusual properties. Such systems have a wide range of potential applications in photonics. We are developing transmission lines composed of superconducting metamaterials using thin-film lumped circuit elements. Such structures allow for the possibility of generating novel transmission spectra with a high density of modes in some frequency ranges and stop-bands in others. We discuss possible couplings of these lines to superconducting qubits in circuit QED architectures.

  13. Creating product line architectures

    OpenAIRE

    Bayer, J.; Flege, O.; Gacek, C.

    2000-01-01

    The creation and validation of product line software architectures are inherently more complex than those of software architectures for single systems. This paper compares a process for creating and evaluating a traditional, one-of-a- kind software architecture with one for a reference software architecture. The comparison is done in the context of PuLSE-DSSA, a customizable process that integrates both product line architecture creation and evaluation.

  14. NLC Extraction Line Studies

    OpenAIRE

    Nosochkov, Y. M.; Raubenheimer, T. O.

    2001-01-01

    In this note, we briefly review the current lattice of the NLC extraction line which was designed for the nominal NLC beam parameters. Then we describe the beam parameters for the high luminosity option with larger beam disruption parameter and discuss its effect on beam loss in the extraction line. Finally, we present a summary of the optics study aimed at minimizing the beam loss with high disruption beams.

  15. On-Line and Off-Line Assessment of Metacognition

    Science.gov (United States)

    Saraç, Seda; Karakelle, Sema

    2012-01-01

    The study investigates the interrelationships between different on-line and off-line measures for assessing metacognition. The participants were 47 fifth grade elementary students. Metacognition was assessed through two off-line and two on-line measures. The off-line measures consisted of a teacher rating scale and a self-report questionnaire. The…

  16. Evidence of Decay of Flux Ratio of Fe to Fe–Ni Line Features with ...

    Indian Academy of Sciences (India)

    We propose that the difference may be due to the consideration of higher densities of Fe and Fe–Ni lines in the theoretical model of Phillips (2004). We suggest revising the Fe and Fe–Ni line densities in the corona. The decay of flux ratio explains the variation of equivalent width and peak energy of these line features with ...

  17. Comprehensive analysis of line-edge and line-width roughness for EUV lithography

    Science.gov (United States)

    Bonam, Ravi; Liu, Chi-Chun; Breton, Mary; Sieg, Stuart; Seshadri, Indira; Saulnier, Nicole; Shearer, Jeffrey; Muthinti, Raja; Patlolla, Raghuveer; Huang, Huai

    2017-03-01

    Pattern transfer fidelity is always a major challenge for any lithography process and needs continuous improvement. Lithographic processes in semiconductor industry are primarily driven by optical imaging on photosensitive polymeric material (resists). Quality of pattern transfer can be assessed by quantifying multiple parameters such as, feature size uniformity (CD), placement, roughness, sidewall angles etc. Roughness in features primarily corresponds to variation of line edge or line width and has gained considerable significance, particularly due to shrinking feature sizes and variations of features in the same order. This has caused downstream processes (Etch (RIE), Chemical Mechanical Polish (CMP) etc.) to reconsider respective tolerance levels. A very important aspect of this work is relevance of roughness metrology from pattern formation at resist to subsequent processes, particularly electrical validity. A major drawback of current LER/LWR metric (sigma) is its lack of relevance across multiple downstream processes which effects material selection at various unit processes. In this work we present a comprehensive assessment of Line Edge and Line Width Roughness at multiple lithographic transfer processes. To simulate effect of roughness a pattern was designed with periodic jogs on the edges of lines with varying amplitudes and frequencies. There are numerous methodologies proposed to analyze roughness and in this work we apply them to programmed roughness structures to assess each technique's sensitivity. This work also aims to identify a relevant methodology to quantify roughness with relevance across downstream processes.

  18. Along the line

    DEFF Research Database (Denmark)

    Dinesen, Cort Ross

    2011-01-01

    Embarking on a work of art constitutes a reduction of information – because we grasp the diversity and plurality of the manifestations we encounter by abstracting them and transforming them into manageable concepts; as we do when we draw contour lines on the landscape – they are imaginary...... and invisible but an abstraction essential for noting a difference or marking a place on a map. In the same way, a stroke in a sketch or a line in the sand is a manifestation of our ability to draw a boundary that both includes and excludes information. Where the line makes the birth of an idea visible......, it expresses through movement our tendency to mark a difference by drawing attention to and enclosing a whole series of relations that confront our preconceived notions. It is in the process of transformation in which we reduce the complexity of how we work, and rethink our ideas anew by refining the very same...

  19. Draw the Line!

    DEFF Research Database (Denmark)

    Draw the Line! International Conference, Copenhagen 2008 Papers, proceedings and recommendations is the second publication of the international three year long project "Understanding Puzzles in the Gendered European Map" (UPGEM), which is financed by the European Commission. In this publication we...... present proceedings from the UPGEM conference "Draw the Line!" in Copenhagen May 2008. The proceedings include contributions by UPGEM researchers, conference speeches by other researchers, politicians and gender equality officers in which they relate their work and research with the research done in UPGEM...... in the national contexts (see Draw the Line! Universities as workplaces for male and female researchers in Europe and http://www.upgem.dk/ ). We have also identified and discussed three scientific cultures in physics across the national borders. We call these scientific cultures: Hercules, Caretakers and Worker...

  20. VT Digital Line Graph Railroads

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of major railroad lines for the state of Vermont. These railroad lines line up well along quadrangle boundaries, but...

  1. Ensembl variation resources

    Directory of Open Access Journals (Sweden)

    Marin-Garcia Pablo

    2010-05-01

    Full Text Available Abstract Background The maturing field of genomics is rapidly increasing the number of sequenced genomes and producing more information from those previously sequenced. Much of this additional information is variation data derived from sampling multiple individuals of a given species with the goal of discovering new variants and characterising the population frequencies of the variants that are already known. These data have immense value for many studies, including those designed to understand evolution and connect genotype to phenotype. Maximising the utility of the data requires that it be stored in an accessible manner that facilitates the integration of variation data with other genome resources such as gene annotation and comparative genomics. Description The Ensembl project provides comprehensive and integrated variation resources for a wide variety of chordate genomes. This paper provides a detailed description of the sources of data and the methods for creating the Ensembl variation databases. It also explores the utility of the information by explaining the range of query options available, from using interactive web displays, to online data mining tools and connecting directly to the data servers programmatically. It gives a good overview of the variation resources and future plans for expanding the variation data within Ensembl. Conclusions Variation data is an important key to understanding the functional and phenotypic differences between individuals. The development of new sequencing and genotyping technologies is greatly increasing the amount of variation data known for almost all genomes. The Ensembl variation resources are integrated into the Ensembl genome browser and provide a comprehensive way to access this data in the context of a widely used genome bioinformatics system. All Ensembl data is freely available at http://www.ensembl.org and from the public MySQL database server at ensembldb.ensembl.org.

  2. Variational Transition State Theory

    Energy Technology Data Exchange (ETDEWEB)

    Truhlar, Donald G. [Univ. of Minnesota, Minneapolis, MN (United States)

    2016-09-29

    This is the final report on a project involving the development and applications of variational transition state theory. This project involved the development of variational transition state theory for gas-phase reactions, including optimized multidimensional tunneling contributions and the application of this theory to gas-phase reactions with a special emphasis on developing reaction rate theory in directions that are important for applications to combustion. The development of variational transition state theory with optimized multidimensional tunneling as a useful computational tool for combustion kinetics involved eight objectives.

  3. Software product lines

    OpenAIRE

    Cortés Verdín, María Karen

    2005-01-01

    A Software Product Line is a “set of software-intensive systems sharing a common, managed set of features that satisfy the specific needs of a particular market segment or mission and that are developed from a common set of core assets in a prescribed way”1. A software product line (or software product family) approach promotes planned and proactive reuse of core assets and architecture-centric development, achieving a substantial increment in product quality and a reduced time to market. Bec...

  4. BPL (Broadband Power Line)

    OpenAIRE

    Peralta, Arturo

    2010-01-01

    El mundo actual requiere cada vez más el estar conectados con la sociedad de la Información y el Conocimiento, esto demanda que en los hogares, lugares de turismo, trabajos, universidades, etcétera, se cuente con una conexión a Internet de Alta Velocidad, que además sea segura y confiable. En este documento se presenta las características más importantes de la tecnología BPL (Broadband Power Line) o PLC (Power Line Comunication), la cual permite brindar el servicio de Internet ...

  5. Non-LTE hydrogen-line formation in moving prominences

    Science.gov (United States)

    Heinzel, P.; Rompolt, B.

    1986-01-01

    The behavior of hydrogen-line brightness variations, depending on the prominence-velocity changes were investigated. By solving the NON-Local thermodynamic equilibrium (LTE) problem for hydrogen researchers determine quantitatively the effect of Doppler brightening and/or Doppler dimming (DBE, DDE) in the lines of Lyman and Balmer series. It is demonstrated that in low-density prominence plasmas, DBE in H alpha and H beta lines can reach a factor of three for velocities around 160 km/sec, while the L alpha line exhibits typical DDE. L beta brightness variations follow from a combined DBE in the H alpha and DDE in L alpha and L beta itself, providing that all relevant multilevel interlocking processes are taken into account.

  6. Saturn chorus latitudinal variations

    National Research Council Canada - National Science Library

    Menietti, J. D; Hospodarsky, G. B; Shprits, Y. Y; Gurnett, D. A

    2014-01-01

    The variation of propagation properties of whistler mode chorus as a function of latitude is not well known at Saturn but is important for the calculation of pitch angle diffusion and nonlinear growth of chorus...

  7. Variation within categories.

    NARCIS (Netherlands)

    Das-Smaal, E.A.; Swart, de J.H.

    1984-01-01

    Two aspects of variation within categories, relating to different models of categorization, were investigated - frequency of dimensional values and typicality differences within values. The influence of range of typicality experienced during learning and of informational value of feedback was also

  8. Variational principles in physics

    CERN Document Server

    Basdevant, Jean-Louis

    2007-01-01

    Optimization under constraints is an essential part of everyday life. Indeed, we routinely solve problems by striking a balance between contradictory interests, individual desires and material contingencies. This notion of equilibrium was dear to thinkers of the enlightenment, as illustrated by Montesquieu’s famous formulation: "In all magistracies, the greatness of the power must be compensated by the brevity of the duration." Astonishingly, natural laws are guided by a similar principle. Variational principles have proven to be surprisingly fertile. For example, Fermat used variational methods to demonstrate that light follows the fastest route from one point to another, an idea which came to be known as Fermat’s principle, a cornerstone of geometrical optics. Variational Principles in Physics explains variational principles and charts their use throughout modern physics. The heart of the book is devoted to the analytical mechanics of Lagrange and Hamilton, the basic tools of any physicist. Prof. Basdev...

  9. Absolute Poverty Lines

    DEFF Research Database (Denmark)

    Arndt, Channing; Mahrt, Kristi; Tarp, Finn

    2017-01-01

    ’ approach, employing multiple methods, is the best available mode for addressing these limitations. A first fundamental choice is whether to estimate an absolute poverty line at all. Consumption-based poverty metrics provide only a partial view into the welfare of individuals or households, which may or may...

  10. Bike Map Lines

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — Chapel Hill Bike Map Lines from KMZ file.This data came from the wiki comment board for the public, not an “official map” showing the Town of Chapel Hill's plans or...

  11. Clamp Restrains Pressure Line

    Science.gov (United States)

    Aliberti, J. A.

    1982-01-01

    Safety restraint protects people and property if a high-pressure fitting fails. As long as pressure line remains attached at the fitting, clamp exerts essentially no force on hose. If fitting fails, force of fluid leaving free end of hose causes the cam on the clamp to compress hose with a positive locking action.

  12. Analysis of () Line Shape

    Indian Academy of Sciences (India)

    The line shape is also simulated by the Monte–Carlo method, the molecular dissociation contributes to 57% neutral atoms and 53% emission intensity in front of the limiter, and 85% neutral atoms and 82% emission intensity in front of the wall. The processes of atoms and molecules influence on the energy balance is ...

  13. Subjective poverty line definitions

    NARCIS (Netherlands)

    J. Flik; B.M.S. van Praag (Bernard)

    1991-01-01

    textabstractIn this paper we will deal with definitions of subjective poverty lines. To measure a poverty threshold value in terms of household income, which separates the poor from the non-poor, we take into account the opinions of all people in society. Three subjective methods will be discussed

  14. LEAR: antiproton extraction lines

    CERN Document Server

    Photographic Service

    1992-01-01

    Antiprotons, decelerated in LEAR to a momentum of 100 MeV/c (kinetic energy of 5.3 MeV), were delivered to the experiments in an "Ultra-Slow Extraction", dispensing some 1E9 antiprotons over times counted in hours. Beam-splitters and a multitude of beam-lines allowed several users to be supplied simultaneously.

  15. Automatic transmission line monitor

    Science.gov (United States)

    Parsons, W. E.; Richards, L. O.

    1971-01-01

    Monitor improves complex network reliability in computer data links and command transmission lines. System evaluates circuit performance against preselected criteria, identifies and stores data indicating out-of-tolerance conditions, conducts closed loop testing, and provides for operation under command of digital computer that determines restoration priorities.

  16. Drawing the Line

    DEFF Research Database (Denmark)

    Holm, Isak Winkel

    2016-01-01

    of judgement that distinguishes between the inside and outside of a political community, between citizens and zombies. Second, the chapter focuses on the rhetorics applied to draw the line between rights-bearers and the rightless. ‘Prophetic’ speech, echoing the language of the Old Testament prophets, is vital...

  17. Developing Green Line Products

    DEFF Research Database (Denmark)

    Muñoz-Marin, Ana Maria; Lassen, Astrid Heidemann; Poulsen, Søren Bolvig

    2011-01-01

    This publication is based on the Master thesis “User-driven ecoinnovation process: Towards the implementation of the Green product line at JELD-WEN” written by Ana Maria Muñoz-Marin as her Graduation Project for the MSc. Global Innovation Management degree. The company-based experiment was carried...

  18. America's Assembly Line

    DEFF Research Database (Denmark)

    Nye, David Edwin

    A social history of the assembly line, invented in 1913. Both praised as a boon to consumers and as a curse for workers, it has been satirized, imitated, and celebrated for 100 years. It has inspired fiction, comedy, cafeteria layouts, and suburban housing. It transformed industrial labor...

  19. Generalized quasi variational inequalities

    Energy Technology Data Exchange (ETDEWEB)

    Noor, M.A. [King Saud Univ., Riyadh (Saudi Arabia)

    1996-12-31

    In this paper, we establish the equivalence between the generalized quasi variational inequalities and the generalized implicit Wiener-Hopf equations using essentially the projection technique. This equivalence is used to suggest and analyze a number of new iterative algorithms for solving generalized quasi variational inequalities and the related complementarity problems. The convergence criteria is also considered. The results proved in this paper represent a significant improvement and refinement of the previously known results.

  20. Germanic Verb Particle Variation

    DEFF Research Database (Denmark)

    Vikner, Sten

    2017-01-01

    This paper has two closely related goals. The more "global" one is to present an overview of the variation conceming verb particles across the Germanic languages (see e.g. den Dikken 1995; Haiden 2005; Mclntyre 2007 and many others), and the more "local" one is to use some of this variation data ...... to argue for Yiddish being an SOV-language like German and Dutch rather than an SVO-language like English and the Scandinavian languages....

  1. Variation in Metaphor Variation in Metaphor

    Directory of Open Access Journals (Sweden)

    Zóltan Kövecses

    2010-05-01

    Full Text Available

    Cognitive linguists have so far paid a great deal of attention to the emarkable universality of many conceptual metaphors. However, their theories fail to account for the equally impressive diversity of metaphorical conceptualization both across and within cultures. The present paper is an attempt to lay down the foundations of a theory of metaphor that is capable of simultaneously accounting for both universality and variation in metaphor.

     

    Cognitive linguists have so far paid a great deal of attention to the emarkable universality of many conceptual metaphors. However, their theories fail to account for the equally impressive diversity of metaphorical conceptualization both across and within cultures. The present paper is an attempt to lay down the foundations of a theory of metaphor that is capable of simultaneously accounting for both universality and variation in metaphor.

  2. Ultra-metal-poor Stars: Spectroscopic Determination of Stellar Atmospheric Parameters Using Iron Non-LTE Line Abundances

    Science.gov (United States)

    Ezzeddine, Rana; Frebel, Anna; Plez, Bertrand

    2017-10-01

    We present new ultra-metal-poor stars parameters with [Fe/H] LTE in their atmospheric parameters and show that they can grow up to ˜1.00 dex in [Fe/H], ˜150 K in {T}{eff} and ˜0.5 dex in log g toward the lowest metallicities. Accurate NLTE atmospheric stellar parameters, in particular [Fe/H] being significantly higher, are the first step to eventually providing full NLTE abundance patterns that can be compared with Population III supernova nucleosynthesis yields to derive properties of the first stars. Overall, this maximizes the potential of these likely second-generation stars to investigate the early universe and how the chemical elements were formed.

  3. Directed Line Liquids

    Science.gov (United States)

    Kamien, Randall David

    This thesis is devoted to the study of ensembles of dense directed lines. These lines are principally to be thought of as polymers, though they also have the morphology of flux lines in high temperature superconductors, strings of colloidal spheres in electrorheological fluids and the world lines of quantum mechanical bosons. We first study nematic polymers dissolved in a nematic solvent. We show that in the dense phase nematic polymers interacting directly through excluded volume and indirectly through nematic solvent fluctuations are, at long wavelengths, identical to nematic polymers in an isotropic solvent, interacting through, again, excluded volume as well as their nematic degrees of freedom. By including the effects of free ends we study ferro- and electrorheological fluids and finite chain length polymers. In the dilute phase, near the transition to the semi-dilute phase, a renormalization group treatment is performed, in the physical and critical dimension 3. For sufficiently dilute systems we find logarithmic corrections to polymer wandering, predicted by de Gennes. However, at higher densities, the logarithmic enhancement is suppressed, and the polymers execute conventional random walks along the preferred axis. We then study the isotropic to nematic transition in this same system of liquid-crystalline polymers. Using the replica technique introduced by de Gennes to study isotropic polymers, we formulate a fully isotropic theory of liquid-crystalline polymers dissolved in a liquid crystal matrix. The first order transition from isotropic to nematic ordering occurs, and leads to the original directed polymer theory previously studied. In agreement with physical expectations, the nematic ordering temperature is depressed by polymerization. Finally, we go back to directed systems, in this case directed by an explicit symmetry violation instead of spontaneously. We discuss how directed polymer melts, string-like formations in electrorheological and ferro

  4. Multiple Lines of Evidence

    Energy Technology Data Exchange (ETDEWEB)

    Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Venzin, Alexander M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bramer, Lisa M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-03

    This paper discusses the process of identifying factors that influence the contamination level of a given decision area and then determining the likelihood that the area remains unacceptable. This process is referred to as lines of evidence. These lines of evidence then serve as inputs for the stratified compliance sampling (SCS) method, which requires a decision area to be divided into strata based upon contamination expectations. This is done in order to focus sampling efforts more within stratum where contamination is more likely and to use the domain knowledge about these likelihoods of the stratum remaining unacceptable to buy down the number of samples necessary, if possible. Two different building scenarios were considered as an example (see Table 3.1). SME expertise was elicited concerning four lines of evidence factors (see Table 3.2): 1) amount of contamination that was seen before decontamination, 2) post-decontamination air sampling information, 3) the applied decontaminant information, and 4) the surface material. Statistical experimental design and logistic regression modelling were used to help determine the likelihood that example stratum remained unacceptable for a given example scenario. The number of samples necessary for clearance was calculated by applying the SCS method to the example scenario, using the estimated likelihood of each stratum remaining unacceptable as was determined using the lines of evidence approach. The commonly used simple random sampling (SRS) method was also used to calculate the number of samples necessary for clearance for comparison purposes. The lines of evidence with SCS approach resulted in a 19% to 43% reduction in total number of samples necessary for clearance (see Table 3.6). The reduction depended upon the building scenario, as well as the level of percent clean criteria. A sensitivity analysis was also performed showing how changing the estimated likelihoods of stratum remaining unacceptable affect the number

  5. A Quantitative Transmission Line Experiment

    Science.gov (United States)

    Johnston, D. C.; Silbernagel, B. G.

    1969-01-01

    Describes modifications of a commercially available strip-type transmission line, which makes possible reproducible measurements of standing waves on the line. Experimental data yield values for the characteristic impedance, phase velocity and line wavelength of radiation in the transmission line, and the dielectric constant of material in the…

  6. The Bicycle Assembly Line Game

    Science.gov (United States)

    Klotz, Dorothy

    2011-01-01

    "The Bicycle Assembly Line Game" is a team-based, in-class activity that helps students develop a basic understanding of continuously operating processes. Each team of 7-10 students selects one of seven prefigured bicycle assembly lines to operate. The lines are run in real-time, and the team that operates the line that yields the…

  7. Printed circuit dispersive transmission line

    Science.gov (United States)

    Ikezi, Hiroyuki; Lin-Liu, Yuh-Ren; DeGrassie, John S.

    1991-01-01

    A printed circuit dispersive transmission line structure is disclosed comprising an insulator, a ground plane formed on one surface of the insulator, a first transmission line formed on a second surface of the insulator, and a second transmission line also formed on the second surface of the insulator and of longer length than the first transmission line and periodically intersecting the first transmission line. In a preferred embodiment, the transmission line structure exhibits highly dispersive characteristics by designing the length of one of the transmission line between two adjacent periodic intersections to be longer than the other.

  8. Fuel line purging device

    Energy Technology Data Exchange (ETDEWEB)

    Hensel, R.J.

    1988-03-22

    In a fuel injection system for an internal combustion engine having a fuel pump communicating with a fuel tank and delivering pressurized fuel through a pressure line to a fuel injector, the improvement is described comprising purging means for purging gas, including air and vapor, from the system, comprising: a housing having an inlet communicating with the pressure line, and having an outlet; pressure responsive valve means in the housing movable between an open position permitting flow from the inlet to the outlet, and a closed position blocking flow from the inlet to the outlet; a first branch passage in the housing communicating between the inlet and one side of the valve means; a second branch passage in the housing communicating between the inlet and the other side of the valve means; restriction means in the second branch passage selected to provide a fuel pressure drop thereacross but not substantially dropping gas pressure thereacross.

  9. Adaptive method of lines

    CERN Document Server

    Saucez, Ph

    2001-01-01

    The general Method of Lines (MOL) procedure provides a flexible format for the solution of all the major classes of partial differential equations (PDEs) and is particularly well suited to evolutionary, nonlinear wave PDEs. Despite its utility, however, there are relatively few texts that explore it at a more advanced level and reflect the method''s current state of development.Written by distinguished researchers in the field, Adaptive Method of Lines reflects the diversity of techniques and applications related to the MOL. Most of its chapters focus on a particular application but also provide a discussion of underlying philosophy and technique. Particular attention is paid to the concept of both temporal and spatial adaptivity in solving time-dependent PDEs. Many important ideas and methods are introduced, including moving grids and grid refinement, static and dynamic gridding, the equidistribution principle and the concept of a monitor function, the minimization of a functional, and the moving finite elem...

  10. Draw the Line!

    DEFF Research Database (Denmark)

    present proceedings from the UPGEM conference "Draw the Line!" in Copenhagen May 2008. The proceedings include contributions by UPGEM researchers, conference speeches by other researchers, politicians and gender equality officers in which they relate their work and research with the research done in UPGEM......Draw the Line! International Conference, Copenhagen 2008 Papers, proceedings and recommendations is the second publication of the international three year long project "Understanding Puzzles in the Gendered European Map" (UPGEM), which is financed by the European Commission. In this publication we....... The UPGEM research has previously been published in national reports from each of the partner countries (Denmark, Estonia, Finland, Italy and Poland). In these individual national reports of universities as workplaces for male and female researchers we discuss scientific cultures in physics embedded...

  11. Drill string transmission line

    Science.gov (United States)

    Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Bradford, Kline; Fox, Joe

    2006-03-28

    A transmission line assembly for transmitting information along a downhole tool comprising a pin end, a box end, and a central bore traveling between the pin end and the box end, is disclosed in one embodiment of the invention as including a protective conduit. A transmission line is routed through the protective conduit. The protective conduit is routed through the central bore and the ends of the protective conduit are routed through channels formed in the pin end and box end of the downhole tool. The protective conduit is elastically forced into a spiral or other non-linear path along the interior surface of the central bore by compressing the protective conduit to a length within the downhole tool shorter than the protective conduit.

  12. Structural variations in pig genomes

    NARCIS (Netherlands)

    Paudel, Y.

    2015-01-01

    Abstract Paudel, Y. (2015). Structural variations in pig genomes. PhD thesis, Wageningen University, the Netherlands Structural variations are chromosomal rearrangements such as insertions-deletions (INDELs), duplications, inversions, translocations, and copy number variations

  13. Hydrogen Stark Broadened Brackett lines

    Directory of Open Access Journals (Sweden)

    C. Stehlé

    2010-01-01

    Full Text Available Stark-broadened lines of the hydrogen Brackett series are computed for the conditions of stellar atmospheres and circumstellar envelopes. The computation is performed within the Model Microfield Method, which includes the ion dynamic effects and makes the bridge between the impact limit at low density and the static limit at high density and in the line wings. The computation gives the area normalized line shape, from the line core up to the static line wings.

  14. Line managers as marketers.

    Science.gov (United States)

    Rynne, T J

    1986-09-01

    Many hospital administrators and boards of directors, having overcome their initial opposition to advertising and hired a marketing professional, are wondering why their marketing programs have not accomplished all that they had hoped. The answer lies in their perception of who is responsible for marketing. Marketing is not a specialty separate from the disciplines of management--it is a basic management skill. Its goal is to satisfy the customer by providing products and services that meet the customer's needs, wants, and preferences. Line managers must understand the hospital's customers and make the critical day-to-day differences in satisfying them. They are the hospital's front-line marketers, and the marketing department's role is to support them in this function. The marketing department should develop the line managers' marketing skills by furnishing them with the appropriate tools: formats, models, examples, and instructions. In addition, the marketing staff should provide such specialized services as marketing research, ad agency management, and development of communications.

  15. Variation and Synthetic Speech

    CERN Document Server

    Miller, C; Massey, N; Miller, Corey; Karaali, Orhan; Massey, Noel

    1997-01-01

    We describe the approach to linguistic variation taken by the Motorola speech synthesizer. A pan-dialectal pronunciation dictionary is described, which serves as the training data for a neural network based letter-to-sound converter. Subsequent to dictionary retrieval or letter-to-sound generation, pronunciations are submitted a neural network based postlexical module. The postlexical module has been trained on aligned dictionary pronunciations and hand-labeled narrow phonetic transcriptions. This architecture permits the learning of individual postlexical variation, and can be retrained for each speaker whose voice is being modeled for synthesis. Learning variation in this way can result in greater naturalness for the synthetic speech that is produced by the system.

  16. On-line inspection of textile geometries

    Science.gov (United States)

    Bahners, Thomas; Ringens, Werner; Schollmeyer, Eckhard

    1993-02-01

    Two examples of specific design philosophies for low-cost on-line inspection systems for textiles are described in this paper: The application of the moire-technique can heavily enhance the imaging of textile surfaces as a filter for the assessment of geometric variations of the textile `grating' with extremely simple algorithms for image analysis. Blinded for color shades triangulation sensors have been developed into powerful tools for fast profiling of textile surfaces. Curtailed for certain applications fiber optical modifications of the basic triangulation principle have been developed for aereal inspection.

  17. Acoustic power balance in lined ducts

    Science.gov (United States)

    Eversman, W.

    1979-01-01

    It is shown that the two common definitions of acoustic energy density and intensity in uniform unlined ducts carrying uniform flow are compatible to the extent that both energy densities can be used in an appropriate variational principle to derive the convected wave equation. When the duct walls are lined both energy densities must be modified to account for the wall energy density. This results in a new energy conservation equation which utilizes a modified definition of axial power and accounts for wall dissipation. Computations in specific cases demonstrate the validity of the modified acoustic energy relation.

  18. Splines and variational methods

    CERN Document Server

    Prenter, P M

    2008-01-01

    One of the clearest available introductions to variational methods, this text requires only a minimal background in calculus and linear algebra. Its self-contained treatment explains the application of theoretic notions to the kinds of physical problems that engineers regularly encounter. The text's first half concerns approximation theoretic notions, exploring the theory and computation of one- and two-dimensional polynomial and other spline functions. Later chapters examine variational methods in the solution of operator equations, focusing on boundary value problems in one and two dimension

  19. Ladder Variational Autoencoder

    DEFF Research Database (Denmark)

    Sønderby, Casper Kaae; Raiko, Tapani; Maaløe, Lars

    2016-01-01

    Variational autoencoders are powerful models for unsupervised learning. However deep models with several layers of dependent stochastic variables are difficult to train which limits the improvements obtained using these highly expressive models. We propose a new inference model, the Ladder...... Variational Autoencoder, that recursively corrects the generative distribution by a data dependent approximate likelihood in a process resembling the recently proposed Ladder Network. We show that this model provides state of the art predictive log-likelihood and tighter log-likelihood lower bound compared...

  20. Ladder variational autoencoders

    DEFF Research Database (Denmark)

    Sønderby, Casper Kaae; Raiko, Tapani; Maaløe, Lars

    2016-01-01

    Variational autoencoders are powerful models for unsupervised learning. However deep models with several layers of dependent stochastic variables are difficult to train which limits the improvements obtained using these highly expressive models. We propose a new inference model, the Ladder...... Variational Autoencoder, that recursively corrects the generative distribution by a data dependent approximate likelihood in a process resembling the recently proposed Ladder Network. We show that this model provides state of the art predictive log-likelihood and tighter log-likelihood lower bound compared...

  1. Porosity variation in chalk

    DEFF Research Database (Denmark)

    Lind, Ida; Grøn, Peter

    1996-01-01

    Vertical porosity variations in chalk are generally assumed to result from either a vaguely defined combination of primary sedimentary and diagenetic processes or solely to diagenetic processes. In this study, image analysis of backscatter electron images of polished samples and geochemical...

  2. Seasonal Variation in Epidemiology

    Science.gov (United States)

    Marrero, Osvaldo

    2013-01-01

    Seasonality analyses are important in medical research. If the incidence of a disease shows a seasonal pattern, then an environmental factor must be considered in its etiology. We discuss a method for the simultaneous analysis of seasonal variation in multiple groups. The nuts and bolts are explained using simple trigonometry, an elementary…

  3. Bounded variation and around

    CERN Document Server

    Appell, Jürgen; Merentes Díaz, Nelson José

    2013-01-01

    This monographis a self-contained exposition of the definition and properties of functionsof bounded variation and their various generalizations; the analytical properties of nonlinear composition operators in spaces of such functions; applications to Fourier analysis, nonlinear integral equations, and boundary value problems. The book is written for non-specialists. Every chapter closes with a list of exercises and open problems.

  4. Fluency Variation in Adolescents

    Science.gov (United States)

    De Andrade, Claudia Regina Furquim; Martins, Vanessa De Oliveira

    2007-01-01

    The Speech Fluency Profile of fluent adolescent speakers of Brazilian Portuguese, were examined with respect to gender and neurolinguistic variations. Speech samples of 130 male and female adolescents, aged between 12;0 and 17;11 years were gathered. They were analysed according to type of speech disruption; speech rate; and frequency of speech…

  5. Variation in decision making

    NARCIS (Netherlands)

    Dall, Sasha R. X.; Gosling, Samuel; Gordon D.A., Brown,; Dingemanse, Niels; Ido, Erev,; Martin, Kocher,; Laura, Schulz,; Todd, Peter M; Weissing, Franz; Wolf, Max; Hammerstein, Peter; Stevens, Jeffrey R.

    2012-01-01

    Variation in how organisms allocate their behavior over their lifetimes is key to determining Darwinian fitness., and thus the evolution of human and nonhuman decision making. This chapter explores how decision making varies across biologically and societally significant scales and what role such

  6. Variational transition state theory

    Energy Technology Data Exchange (ETDEWEB)

    Truhlar, D.G. [Univ. of Minnesota, Minneapolis (United States)

    1993-12-01

    This research program involves the development of variational transition state theory (VTST) and semiclassical tunneling methods for the calculation of gas-phase reaction rates and selected applications. The applications are selected for their fundamental interest and/or their relevance to combustion.

  7. Intronic variation at the

    NARCIS (Netherlands)

    Trimbos, K.B.; Kentie, R.; van der Velde, M.; Hooijmeijer, J.C.E.W.; Poley, C.; Musters, C.J.M.; de Snoo, G.R.; Piersma, T.

    2013-01-01

    Recently, Schroeder etal. (2010, Ibis 152: 368-377) suggested that intronic variation in the CHD1-Z gene of Black-tailed Godwits breeding in southwest Friesland, The Netherlands, correlated with fitness components. Here we re-examine this surprising result using an expanded dataset (2088 birds

  8. Correlated behavioral traits in rats of the Roman selection lines

    NARCIS (Netherlands)

    Coppens, Caroline M.; de Boer, Sietse F.; Steimer, Thierry; Koolhaas, Jaap M.

    The current theories of animal personality are based on the observation that individual variation in behavior and physiology appears to be consistent across contexts. Rats of the Roman selection lines have been originally selected for differences in shuttle-box behavior. Besides differences in

  9. Variation on the magnetic field profiles of transmission lines for various surrounding conditions calculated by the finite element method; Variacion de los perfiles de campo magnetico en lineas de transmision en diversas condiciones del entorno calculadas mediante el metodo de elementos finitos

    Energy Technology Data Exchange (ETDEWEB)

    Ponta, Fernando; Ferreira, Fabiana

    2001-07-01

    This paper applies the finite element method for the calculation of line magnetic field transversal profile using own routine calculation. Using a real case, simulations were performed under various conditions gathering distortion elements, obtaining the field profile. By analysing these results conclusions are drawing related to the changes produced by the distortions on the magnetic field configuration and evaluations of the surrounding elements influence are evaluated.

  10. LINE BALANCING IN SERVICES

    Directory of Open Access Journals (Sweden)

    Hadi GÖKÇEN

    2002-01-01

    Full Text Available This paper investigates how the Assembly Line Balancing (ALB methods known for the production systems can be applied in service systems. For this purpose, an application study is done in a Physical therapy and rehabilitation clinic. Each standart service provided to patients is taken into consideration as a product, and problem is solved as a mixed model ALB problem. In conclusion, it is seen that the ALB methods developed for the production systems are also applicable in service systems. So, it is possible to do similar studies at hospitals, tax offices, driving licence and passport offices, fast food restaurants, etc.

  11. America's Assembly Line

    DEFF Research Database (Denmark)

    Nye, David Edwin

    A social history of the assembly line, invented in 1913. Both praised as a boon to consumers and as a curse for workers, it has been satirized, imitated, and celebrated for 100 years. It has inspired fiction, comedy, cafeteria layouts, and suburban housing. It transformed industrial labor...... and provoked strikes and union drives in the 1930s, but became a symbol of victory in the Second World War and Cold War. Reinvented by Japan as "lean production" and then increasingly automated after 1990, it remains a cornerstone of production but no longer employs many workers, even as it evolves toward...

  12. [Spectral line shift property of prism dispersive imaging spectrometer].

    Science.gov (United States)

    Zhang, Jun-qiang; Yan, Chang-xiang; Zheng, Yu-quan; Wu, Qing wen

    2011-12-01

    In order to study the spectral line shift property of prism-dispersive imaging spectrometer, the influencing factors and mechanisms of spectral line shift were presented, and the mathematical model based on linear optics model was established to describe the spectral line shift property. Code V API functions was used, in Matlab environment, to verify the validity of mathematical model, and the sensitivity coefficient of spectral line shift was analyzed. Results indicate that rigid body motion of optical mirror surface generated by environmental variation is the key causation of spectral line shift. When the decenter of mirror surface is no more than 0.2 mm and the tilt is less than 0.02 degrees, the value of spectral line shift of different wavelengths at different fields is equivalent, and the error is less than 0.1 pixel. Spectral line shift due to mirror rigid body motion is linear and independent, and the total shift of the spectral line is the algebraic sum of values produced by the single freedom of motion (DOF) of single mirror surface. The mathematical model based on linear optics model can be used to study the spectral line shift property of the prism-dispersive imaging spectrometer. It will provide some guidance for spectral calibration and spectral property analysis under complex work condition.

  13. From Off-line to On-line Handwriting Recognition

    NARCIS (Netherlands)

    Lallican, P.; Viard-Gaudin, C.; Knerr, S.

    2004-01-01

    On-line handwriting includes more information on time order of the writing signal and on the dynamics of the writing process than off-line handwriting. Therefore, on-line recognition systems achieve higher recognition rates. This can be concluded from results reported in the literature, and has been

  14. Genetic analysis of environmental variation

    NARCIS (Netherlands)

    Hill, W.G.; Mulder, H.A.

    2010-01-01

    Environmental variation (VE) in a quantitative trait – variation in phenotype that cannot be explained by genetic variation or identifiable genetic differences – can be regarded as being under some degree of genetic control. Such variation may be either between repeated expressions of the same trait

  15. Strategic production line synchronisation

    Directory of Open Access Journals (Sweden)

    Hattingh, Teresa

    2016-08-01

    Full Text Available A study was conducted at the sole global producer of suspension struts for a particular vehicle manufacturer. This supplier is currently able to meet customer demand. However, it does so because of a large finished goods and work-in-progress (WIP inventory. The plant operates two production processes that are separated by a large buffer of WIP, which essentially decouples the production processes. This study aimed to reduce this WIP buffer; this would require the processes to become synchronised, bearing in mind that the reliability of delivery should not decrease. A tool that considers time, quality, and machine capacity was developed to assess the impact of line synchronisation on company performance figures. It was found that line synchronisation produced several benefits for the supplier, including batch size reduction, lower inventory levels, and associated shorter lead times. This further allowed the supplier to improve flow in the plant by introducing a pull system. Improved visual oversight could lead to further improved problem-solving and innovation.

  16. A Revised Broad-line Region Radius and Black Hole Mass for the Narrow-line Seyfert 1 NGC 4051

    DEFF Research Database (Denmark)

    Denney, K. D.; Watson, L. C.; Peterson, B. M.

    2009-01-01

    ) radius and the optical continuum luminosity—the R BLR-L relationship. Our new measurements of the lag time between variations in the continuum and Hß emission line made from spectroscopic monitoring of NGC 4051 lead to a measured BLR radius of R BLR = 1.87+0.54 -0.50 light days and black hole mass of M...

  17. Spetroscopic Line-Depth Ratios and Solar Variability

    Science.gov (United States)

    Gray, D.

    The ratios of the central depths of selected spectral lines has proved to be a sensitive index of a star's temperature. Line-depth ratios have been successfully applied to main sequence stars (Gray 1994 P.A.S.P. 106, 1248) as well as giants (Gray &Brown 2001 P.A.S.P., 113, 723). A stellar calibration and subsequent application to solar data over a magnetic cycle gave plausible results (Gray &Livingston 1997 Ap.J., 474, 802), indicating a solar temperature variation ~ 1.5 K. This result is subject to unresolved criticisms. I will review these results and focus on possible meanings of the variations in solar line-depth ratios.

  18. Interaction between Engineered Cementitious Composites Lining and Foundation Subsurface Drain

    Directory of Open Access Journals (Sweden)

    Cleopatra Panganayi

    2011-01-01

    Full Text Available The effect of cyclic loads on the surface profiles of ECC linings cast on foundations comprising crushed stone and compacted soil was investigated. A geotextile was embedded between the crushed stone and ECC lining for some of the samples. After 28 days of water curing, the hardened surfaces were loaded and monitored for roughness and crack development by measuring surface levels and crack widths, respectively. Neither cracking nor significant variations in the lateral profiles were observed on all the samples for all the loads applied. However, significant variations which depended on the foundation types were observed in the vertical profiles. It was concluded that while ECC can resist cracking due to its high strain capacity, its flexibility causes ECC linings to assume the shape of the foundation material, which can increase the surface roughness at certain loading configurations.

  19. Central Venous Catheter (Central Line)

    Science.gov (United States)

    ... venous catheter (KATHeter), also known as a central line or CVC, is long, soft, thin, hollow tube ... into a large vein (blood vessel). A central line is much like an intravenous (IV) catheter that ...

  20. Credit Lines and Credit Utilization

    OpenAIRE

    Agarwal, Sumit; Ambrose, Brent W.; Liu, Chunlin

    2006-01-01

    While much is known about the characteristics of consumers or businesses that obtain credit lines, relatively little is known empirically about credit line utilization after origination. This study fills that gap by testing two interrelated hypotheses concerning borrower credit quality and credit line utilization. The empirical analysis confirms that borrowers with higher expectations of future credit quality deterioration originate credit lines to preserve financial flexibility. Furthermore,...

  1. China's Bilateral Currency Swap Lines

    OpenAIRE

    Zhitao, Lin; Wenjie, Zhan; Cheung, Yin-Wong

    2016-01-01

    We study the determinants of China’s bilateral local currency swap lines that were established since the recent global finance crisis. It is found that economic factors, political considerations, and institutional characteristics including trade intensity, economic size, strategic partnership, free trade agreement, corruption, and stability affect the decision of signing a swap line agreement. Once a swap line agreement decision is made, the size of the swap line is then mainly affected by tr...

  2. Molecular dynamics study of the nanosized droplet spreading: The effect of the contact line forces on the kinetic energy dissipation

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Hong Min [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of); Kondaraju, Sasidhar [Department of Mechanical Science, Indian Institute of Technology Bhubaneswar, Bhubaneswar, Odisha 751013 (India); Lee, Jung Shin [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of); Suh, Youngho; Lee, Joonho H. [Samsung Electronics, Mechatronics R& D Center, Hwaseong-si, Gyeonggi-do 445-330 (Korea, Republic of); Lee, Joon Sang, E-mail: joonlee@yonsei.ac.kr [Department of Mechanical Engineering, Yonsei University, Seoul 120-749 (Korea, Republic of)

    2017-07-01

    Highlights: • Contact line forces, including friction and spreading forces are directly calculated. • Overall trends of variations in contact line forces during droplet spreading process show characteristics of contact line forces. • Detail relations of contact line forces and atomic kinetics in the contact line provide a clear evidence of the possible energy dissipation mechanism in droplet spreading process. - Abstract: Recent studies have revealed that contact line forces play an important role in the droplet spreading process. Despite their significance, the physics related to them has been studied only indirectly and the effect of contact line forces is still being disputed. We performed a molecular dynamics simulation and mimicked the droplet spreading process at the nanoscale. Based on the results of the simulation, the contact line forces were directly calculated. We found that the forces acting on the bulk and the contact line region showed different trends. Distinct positive and negative forces, contact line spreading, and friction forces were observed near the contact line. We also observed a strong dependency of the atomic kinetics in the contact line region on the variations in the contact line forces. The atoms of the liquid in the contact line region lost their kinetic energy due to the contact line friction force and became partially immobile on the solid surface. The results of the current study will be useful for understanding the role of the contact line forces on the kinetic energy dissipation in the contact line region.

  3. Variation-aware advanced CMOS devices and SRAM

    CERN Document Server

    Shin, Changhwan

    2016-01-01

    This book provides a comprehensive overview of contemporary issues in complementary metal-oxide semiconductor (CMOS) device design, describing how to overcome process-induced random variations such as line-edge-roughness, random-dopant-fluctuation, and work-function variation, and the applications of novel CMOS devices to cache memory (or Static Random Access Memory, SRAM). The author places emphasis on the physical understanding of process-induced random variation as well as the introduction of novel CMOS device structures and their application to SRAM. The book outlines the technical predicament facing state-of-the-art CMOS technology development, due to the effect of ever-increasing process-induced random/intrinsic variation in transistor performance at the sub-30-nm technology nodes. Therefore, the physical understanding of process-induced random/intrinsic variations and the technical solutions to address these issues plays a key role in new CMOS technology development. This book aims to provide the reade...

  4. Software Product Lines : Three Examples

    OpenAIRE

    2000-01-01

    This report presents the results of a course on software product lines. The assignment in the course was to develop a software product line. . During the course, the students had to develop the following artifacts in groups: product line architecture, component designs, product derivations, modifiability assessment and a prototype. The results of the course are described in this report

  5. The Median-Median Line

    Science.gov (United States)

    Wilson, David C.

    2010-01-01

    Graphing bivariate data in a scatter plot and drawing an approximate line of best fit for the data have become commonly recommended activities for middle school and high school students. The graphing calculator has provided a mechanism for students both to approximate a best-fit line and to calculate the best-fit line using a built-in option. Two…

  6. Variation, structure and norms

    DEFF Research Database (Denmark)

    Harder, Peter

    2014-01-01

    After a period when the focus was essentially on mental architecture, the cognitive sciences are increasingly integrating the social dimension. The rise of a cognitive sociolinguistics is part of this trend. The article argues that this process requires a re-evaluation of some entrenched positions...... in the foundations that were the result of suppressing the sociocultural underpinnings of linguistic facts. Structuralism, cognitivism and social constructionism introduced new and necessary distinctions, but in their strong forms they all turned into unnecessary divides. The article tries to show....... Variational patterns should be seen in the context of structural categories without which there would be only ‘differences’ rather than variation. And emergence, individual choice, and flux should be seen in the context of the individual’s dependence on lineages of community practice sustained by collective...

  7. Conformable variational iteration method

    Directory of Open Access Journals (Sweden)

    Omer Acan

    2017-02-01

    Full Text Available In this study, we introduce the conformable variational iteration method based on new defined fractional derivative called conformable fractional derivative. This new method is applied two fractional order ordinary differential equations. To see how the solutions of this method, linear homogeneous and non-linear non-homogeneous fractional ordinary differential equations are selected. Obtained results are compared the exact solutions and their graphics are plotted to demonstrate efficiency and accuracy of the method.

  8. Lines of landscape organisation

    DEFF Research Database (Denmark)

    Løvschal, Mette

    2015-01-01

    This paper offers a landscape analysis of the earliest linear landscape boundaries on Skovbjerg Moraine, Denmark, during the first millennium BC. Using Delaunay triangulation as well as classic distribution analyses, it demonstrates that landscape boundaries articulated already established use......-patterns close to roads, but also intercepted the central lines of movement and conflicted with previous ways of organizing the landscape. This development is interpreted as a different form of large-scale landholding, in which livestock possibly played a dominant role and boundaries were used to confiscate land...... in the zones bordering suitable pastures. This situation shows obvious parallels with southern Britain centuries earlier. It is discussed how the study of these physical boundaries provides new insights into the organization of pre-Roman landscapes, not only demonstrating a continuing engagement with landscape...

  9. Population-level analysis of gut microbiome variation

    NARCIS (Netherlands)

    Falony, Gwen; Joossens, Marie; Vieira-Silva, Sara; Wang, Jun; Darzi, Youssef; Faust, Karoline; Kurilshchikov, Aleksandr; Bonder, Marc Jan; Valles-Colomer, Mireia; Vandeputte, Doris; Tito, Raul Y.; Chaffron, Samuel; Rymenans, Leen; Verspecht, Chlo; De Sutter, Lise; Lima-Mendez, Gipsi; D'hoe, Kevin; Jonckheere, Karl; Homola, Daniel; Garcia, Roberto; Tigchelaar, Ettje F.; Eeckhaudt, Linda; Fu, Jingyuan; Henckaerts, Liesbet; Zhernakova, Alexandra; Wijmenga, Cisca; Raes, Jeroen

    2016-01-01

    Fecal microbiome variation in the average, healthy population has remained under-investigated. Here, we analyzed two independent, extensively phenotyped cohorts: the Belgian Flemish Gut Flora Project (FGFP; discovery cohort; N = 1106) and the Dutch LifeLines-DEEP study (LLDeep; replication; N =

  10. Statics and dynamics of dislocations: A variational approach

    OpenAIRE

    DE LUCA, LUCIA

    2014-01-01

    Dislocations are line defects in the periodic structure of the crystals. In this thesis, we focus the variational analysis of the elastic energy induced by a finite family of dislocations. Moreover, we study the dynamics of a finite system of screw dislocations.

  11. Variation and inter-relationship, between yield and, some agronomic ...

    African Journals Online (AJOL)

    Variation and inter-relationship, between yield and, some agronomic characters in induced rice ( Oryza sativa L.) mutants. ... Twenty three mutant lines in M5 and M6 generations plus two controls were sown in a randomised complete Block Design (RCBD) and replicated three times at the Sokoine University of Agriculture ...

  12. Seasonal variation in phytoplankton in the southern Benguela ...

    African Journals Online (AJOL)

    Pigment indices and satellite imagery were used to investigate the seasonal variation in phytoplankton in the southern Benguela, with the aid of monthly monitoring on two transect lines. Sea surface temperature images revealed the similarity in thermal conditions during autumn, winter and spring, with a broad zone of ...

  13. Climatic and seasonal variations of effective earth radius factor...

    African Journals Online (AJOL)

    2008-04-12

    Apr 12, 2008 ... This gives rise to the concept of 'effective-Earth-radius'. Effective Earth Radius Factor, k. The decrease of N with height, which causes bending of a radio ray ... Ducting Threshold -157 0 oo. Ducting <- 157 <0 00. Variations in k-value can cause significant degradation of line-of-sight (LOS) paths. A temporary ...

  14. A line-profile analysis of the large-amplitude beta Cephei star xi1 Canis Majoris

    NARCIS (Netherlands)

    Saesen, S.; Briquet, M.; Aerts, C.C.

    2006-01-01

    We present a detailed line-profile study of the beta Cephei star xi1 Canis Majoris, for which we have assembled numerous high-resolution spectra over a period of 4.5 years. It is the first time that the line-profile variations of this star have been analysed. We focused on the Si III line profiles

  15. Similarity law for Widom lines and coexistence lines

    Science.gov (United States)

    Banuti, D. T.; Raju, M.; Ihme, M.

    2017-05-01

    The coexistence line of a fluid separates liquid and gaseous states at subcritical pressures, ending at the critical point. Only recently, it became clear that the supercritical state space can likewise be divided into regions with liquidlike and gaslike properties, separated by an extension to the coexistence line. This crossover line is commonly referred to as the Widom line, and is characterized by large changes in density or enthalpy, manifesting as maxima in the thermodynamic response functions. Thus, a reliable representation of the coexistence line and the Widom line is important for sub- and supercritical applications that depend on an accurate prediction of fluid properties. While it is known for subcritical pressures that nondimensionalization with the respective species critical pressures pcr and temperatures Tcr only collapses coexistence line data for simple fluids, this approach is used for Widom lines of all fluids. However, we show here that the Widom line does not adhere to the corresponding states principle, but instead to the extended corresponding states principle. We resolve this problem in two steps. First, we propose a Widom line functional based on the Clapeyron equation and derive an analytical, species specific expression for the only parameter from the Soave-Redlich-Kwong equation of state. This parameter is a function of the acentric factor ω and compares well with experimental data. Second, we introduce the scaled reduced pressure pr* to replace the previously used reduced pressure pr=p /pcr . We show that pr* is a function of the acentric factor only and can thus be readily determined from fluid property tables. It collapses both subcritical coexistence line and supercritical Widom line data over a wide range of species with acentric factors ranging from -0.38 (helium) to 0.34 (water), including alkanes up to n-hexane. By using pr*, the extended corresponding states principle can be applied within corresponding states principle

  16. Genetic and phenotypic variation in reproductive traits of AI boars.

    Science.gov (United States)

    Flowers, William L

    2008-11-01

    The primary objective of this paper is to review our current understanding of phenotypic variation in reproductive traits of AI boars. The proportion of boars that cannot be trained for collection in commercial studs is low and differences among genetic lines are small. In contrast, there is a considerable variation in sperm production and significant differences are present among genotypes. The general pattern is for sperm numbers to increase rapidly between 9 and 13 months of age and then gradually reach a plateau. This initial period of enhanced production occurs over a longer period in some genetic lines, resulting in differences of 30 x 10(9) sperm cells or more per ejaculate. There also are genetic lines of boars that seem to have a high "heat tolerance". Decreases in sperm production during periods of high environmental temperatures average 5-7% in these lines, compared with 15-20% in others. Finally, there are boars currently being used in the industry that are capable of producing exceptional fertility results with low numbers of sperm. Unfortunately, several breeding practices common to swine AI make their routine identification difficult. Based on the phenotypic variation observed in modern terminal sire lines of AI boars, current prospects for influencing sperm production, boar fertility, and mounting behaviours through genetic selection are viewed as being good, moderate to low, and poor, respectively.

  17. Statistical mechanics of the triple contact line.

    Science.gov (United States)

    Louge, Michel Y

    2017-03-01

    We outline a statistical mechanics of the triple gas-solid-liquid contact line on a rough plane. The analysis regards the neighborhood of the line as a solid dotted with cavities. It adopts the simplest mean-field statistical mechanics, in which each cavity is either full or empty, while being connected to near neighbors by thin necks. The theory predicts equilibrium angles for advance and recession in terms of the Young contact angle and the joint statistical distribution of two quantifiable geometrical parameters representing specific neck cross-section and specific cavity opening. It attributes contact angle hysteresis to first-order phase transitions among adjacent cavities, as they collectively imbibe or reject liquid. It also calculates the potential energy barriers that hysteresis erects against overcoming contact line pinning. By determining whether the phase transitions can release latent energy, this ab initio analysis distinguishes six regimes, including two metastable recession states. We compare predictions with data for superhydrophobia on microscopic rods; for hysteresis in the "Wenzel state"; and for variations of the advancing contact angle with surface energies of the liquid.

  18. Hockey lines for simulation-based learning.

    Science.gov (United States)

    Topps, David; Ellaway, Rachel; Kupsh, Christine

    2015-06-01

    Simulation-based health professional education is often limited in accommodating large numbers of students. Most organisations do not have enough simulation suites or staff to support growing demands. We needed to find ways to make simulation sessions more accommodating for larger groups of learners, so that more than a few individuals could be active in a simulation scenario at any one time. Moreover, we needed to make the experience meaningful for all participating learners. We used the metaphor of (ice) hockey lines and substitution 'on the fly' to effectively double the numbers of learners that can be actively engaged at once. Team players must communicate clearly, and observe keenly, so that currently playing members understand what is happening from moment to moment and incoming substitutes can take over their roles seamlessly. Most organisations do not have enough simulation suites or staff to support growing demands We found that this hockey lines approach to simulation-based team scenarios will raise learners' levels of engagement, reinforce good crew resource management (CRM) practices, enhance closed-loop communication, and help learners to understand their cognitive biases and limitations when working in high-pressure situations. During our continuing refinement of the hockey-lines approach, we developed a number of variations on the basic activity model, with various benefits and applications. Both students and teachers have been enthusiastically positive about this approach when it was introduced at our various courses and participating institutions. © 2015 John Wiley & Sons Ltd.

  19. Magnetic Field - Secular Variation of the Inclination Component for the Epoch 2010.0 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer shows lines of equal annual change (secular variation) in the inclination of the Earth's magnetic field, derived from the International Geomagnetic...

  20. 76 FR 51367 - China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Limited; Evergreen Line A...

    Science.gov (United States)

    2011-08-18

    ... China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Limited; Evergreen Line A Joint Service Agreement; Hanjin Shipping Co., Ltd.; Horizon Lines, LLC; Kawasaki Kisen Kaisha, Ltd.; Nippon... Container Lines Co., Ltd.; COSCO Container Lines Company Limited; Evergreen Line A Joint Service Agreement...

  1. Bipolar pulse forming line

    Science.gov (United States)

    Rhodes, Mark A.

    2008-10-21

    A bipolar pulse forming transmission line module for linear induction accelerators having first, second, third, fourth, and fifth planar conductors which form an interleaved stack with dielectric layers between the conductors. Each conductor has a first end, and a second end adjacent an acceleration axis. The first and second planar conductors are connected to each other at the second ends, the fourth and fifth planar conductors are connected to each other at the second ends, and the first and fifth planar conductors are connected to each other at the first ends via a shorting plate adjacent the first ends. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short a high voltage from the first end of the third planar conductor to the first end of the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  2. Impact of gut microbiota on the fly's germ line.

    Science.gov (United States)

    Elgart, Michael; Stern, Shay; Salton, Orit; Gnainsky, Yulia; Heifetz, Yael; Soen, Yoav

    2016-04-15

    Unlike vertically transmitted endosymbionts, which have broad effects on their host's germ line, the extracellular gut microbiota is transmitted horizontally and is not known to influence the germ line. Here we provide evidence supporting the influence of these gut bacteria on the germ line of Drosophila melanogaster. Removal of the gut bacteria represses oogenesis, expedites maternal-to-zygotic-transition in the offspring and unmasks hidden phenotypic variation in mutants. We further show that the main impact on oogenesis is linked to the lack of gut Acetobacter species, and we identify the Drosophila Aldehyde dehydrogenase (Aldh) gene as an apparent mediator of repressed oogenesis in Acetobacter-depleted flies. The finding of interactions between the gut microbiota and the germ line has implications for reproduction, developmental robustness and adaptation.

  3. Spectroscopic Studies of Solar Corona VI: Trend in Line-width ...

    Indian Academy of Sciences (India)

    VI: Trend in Line-width Variation of Coronal Emission Lines with Height Independent of the Structure of Coronal Loops. Jagdev Singh. 1,∗. , Takashi Sakurai. 2. , Kiyoshi Ichimoto. 2. & S. Muneer. 3. 1Indian Institute of Astrophysics, Koramangala, Bangalore 560 034, India. 2National Astronomical Observatory of Japan, ...

  4. Alternate Double Single Track Lines

    Energy Technology Data Exchange (ETDEWEB)

    Moraga Contreras, P.; Grande Andrade, Z.; Castillo Ron, E.

    2016-07-01

    The paper discusses the advantages and shortcomings of alternate double single track (ADST) lines with respect to double track lines for high speed lines. ADST lines consists of sequences of double and single track segments optimally selected in order to reduce the construction and maintenance costs of railway lines and to optimize the timetables used to satisfy a given demand. The single tracks are selected to coincide with expensive segments (tunnels and viaducts) and the double tracks are chosen to coincide with flat areas and only where they are necessary. At the same time, departure times are adjusted for trains to cross at the cheap double track segments. This alternative can be used for new lines and also for existing conventional lines where some new tracks are to be constructed to reduce travel time (increase speed). The ADST proposal is illustrated with some examples of both types (new lines and where conventional lines exist), including the Palencia-Santander, the Santiago-Valparaíso-Viña del Mar and the Dublin-Belfast lines, where very important reductions (90 %) are obtained, especially where a railway infrastructure already exist. (Author)

  5. Characteristics of Seasonal Variation and Solar Activity Dependence of the Geomagnetic Solar Quiet Daily Variation

    Science.gov (United States)

    Shinbori, Atsuki; Koyama, Yukinobu; Nosé, Masahito; Hori, Tomoaki; Otsuka, Yuichi

    2017-10-01

    Characteristics of seasonal variation and solar activity dependence of the X and Y components of the geomagnetic solar quiet (Sq) daily variation at Memambetsu in midlatitudes and Guam near the equator have been investigated using long-term geomagnetic field data with 1 h time resolution from 1957 to 2016. The monthly mean Sq variation in the X and Y components (Sq-X and Sq-Y) shows a clear seasonal variation and solar activity dependence. The amplitude of seasonal variation increases significantly during high solar activities and is proportional to the solar F10.7 index. The pattern of the seasonal variation is quite different between Sq-X and Sq-Y. The result of the correlation analysis between the solar F10.7 index and the Sq-X and Sq-Y shows an almost linear relationship, but the slope of the linear fitted line varies as a function of local time and month. This implies that the sensitivity of Sq-X and Sq-Y to the solar activity is different for different local times and seasons. The pattern of the local time and seasonal variations of Sq-Y at Guam shows good agreement with that of a magnetic field produced by interhemispheric field-aligned currents (FACs), which flow from the summer to winter hemispheres in the dawn and dusk sectors and from the winter to summer hemispheres in the prenoon to afternoon sectors. The direction of the interhemispheric FAC in the dusk sector is opposite to the concept of Fukushima's model.

  6. Variations in brain DNA

    Directory of Open Access Journals (Sweden)

    Jesus eAvila

    2014-11-01

    Full Text Available It is assumed that DNA sequences are conserved in the diverse cell types present in a multicellular organism like the human being. Thus, in order to compare the sequences in the genome of DNA from different individuals, nucleic acid is commonly isolated from a single tissue. In this regard, blood cells are widely used for this purpose because of their availability. Thus blood DNA has been used to study genetic familiar diseases that affect other tissues and organs, such as the liver, heart, and brain. While this approach is valid for the identification of familial diseases in which mutations are present in parental germinal cells and, therefore, in all the cells of a given organism, it is not suitable to identify sporadic diseases in which mutations might occur in specific somatic cells. This review addresses somatic DNA variations in different tissues or cells (mainly in the brain of single individuals and discusses whether the dogma of DNA invariance between cell types is indeed correct. We will also discuss how single nucleotide somatic variations arise, focusing on the presence of specific DNA mutations in the brain.

  7. Gauging Variational Inference

    Energy Technology Data Exchange (ETDEWEB)

    Chertkov, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ahn, Sungsoo [Korea Advanced Inst. Science and Technology (KAIST), Daejeon (Korea, Republic of); Shin, Jinwoo [Korea Advanced Inst. Science and Technology (KAIST), Daejeon (Korea, Republic of)

    2017-05-25

    Computing partition function is the most important statistical inference task arising in applications of Graphical Models (GM). Since it is computationally intractable, approximate methods have been used to resolve the issue in practice, where meanfield (MF) and belief propagation (BP) are arguably the most popular and successful approaches of a variational type. In this paper, we propose two new variational schemes, coined Gauged-MF (G-MF) and Gauged-BP (G-BP), improving MF and BP, respectively. Both provide lower bounds for the partition function by utilizing the so-called gauge transformation which modifies factors of GM while keeping the partition function invariant. Moreover, we prove that both G-MF and G-BP are exact for GMs with a single loop of a special structure, even though the bare MF and BP perform badly in this case. Our extensive experiments, on complete GMs of relatively small size and on large GM (up-to 300 variables) confirm that the newly proposed algorithms outperform and generalize MF and BP.

  8. Multicolor optical Nyquist pulse generation based on self-phase modulation without line-by-line control

    Science.gov (United States)

    Wang, Dong; Huo, Li; Jiang, Xiangyu; Lou, Caiyun

    2016-12-01

    Multicolor optical Nyquist pulse generation based on self-phase modulation without line-by-line control is proposed and experimental demonstrated. By 1.4-ps nearly chirp-free optical Gaussian pulse pumping of a high nonlinearity fiber, a 25-GHz spacing, flat-topped supercontinuum (SC) over 17.8 nm within 3.6 dB power variation at a modest pump power of 21.8 dBm is performed. As the phase of the central 90 tones is almost linear to the wavelength after dispersion compensation, spatial light modulator placed after SC for precise line-by-line control both of amplitude and phase can be replaced by conventional optical band-pass filter (OBPF). With an array of quasi-rectangular OBPFs, nearly transform-limited optical Nyquist pulses with a duty cycle of 5.5% on 4 wavelengths are achieved simultaneously.

  9. Signal Transmission on Power Lines

    DEFF Research Database (Denmark)

    Dalby, Arne Brejning

    1997-01-01

    coupled transmission line circuits like power line circuits, is based on finding the eigenvalues and eigenvectors for the matrix ZY, where Z and Y are the impedance- and admittance matrices for the coupled lines in W/m and S/m. In this paper a flow-graph representation of the relations beween voltage......- and current-vectors is presented for a general coupled line circuit. This flow-graph can be used to find any transfer function on a multiple coupled lossy transmission line circuit. In some cases, however, it is difficult to find the eigenvalues correctly. A correct analysis can thus not be made......In the analysis of power-line networks over a large frequency span, the time-domain method used in programs like EMTP (Electromagnetic Time domain Program) can not be used. A more rigorous analysis method must be employed. The correct analysis method (assuming TEM-mode propagation) for multiple...

  10. Testing in Software Product Lines

    OpenAIRE

    Odia, Osaretin Edwin

    2007-01-01

    This thesis presents research aimed at investigating different activities involved in software product lines testing process and possible improvements towards achieving developing high quality software product lines at reduced cost and time. The research was performed using systematic review procedures of Kitchenham. The reviews carried out in this research covers several areas relating to software product lines testing. The reasons for performing a systematic review in this research are to; ...

  11. Moisture Transport Through Sprayed Concrete Tunnel Linings

    Science.gov (United States)

    Holter, Karl Gunnar; Geving, Stig

    2016-01-01

    Waterproofing of permanent sprayed concrete tunnel linings with sprayed membranes in a continuous sandwich structure has been attempted since 2000 and has seen increased use in some countries. The main function of a sprayed membrane from a waterproofing perspective is to provide crack bridging and hence prevent flow of liquid water into the tunnel through cracks and imperfections in the concrete material. However, moisture can migrate through the concrete and EVA-based membrane materials by capillary and vapor diffusion mechanisms. These moisture transport mechanisms can have an influence on the degree of saturation, and may influence the pore pressures in the concrete material as well as risk of freeze-thaw damage of the concrete and membrane. The paper describes a detailed study of moisture transport material parameters, moisture condition in tunnel linings and climatic conditions tunnels in hard rock in Norway. These data have been included in a hygrothermal simulation model in the software WUFI for moisture transport to substantiate moisture transport and long-term effects on saturation of the concrete and membrane material. The findings suggest that EVA-based membranes exhibit significant water absorption and vapor transport properties although they are impermeable to liquid water flow. State-of-the-art sprayed concrete material applied with the wet mix method exhibits very low hydraulic conductivities, lower than 10-14 m/s, thus saturated conductive water flow is a very unlikely dominant transport mechanism. Moisture transport through the lining structure by capillary flow and vapor diffusion are calculated to approximately 3 cm3/m2 per day for lining thicknesses in the range of 25-35 cm and seasonal Nordic climate variations. The calculated moisture contents in the tunnel linings from the hygrothermal simulations are largely in agreement with the measured moisture contents in the tunnel linings. The findings also indicate that the concrete material exhibits

  12. ExoMol line list - XXI. Nitric Oxide (NO)

    Science.gov (United States)

    Wong, Andy; Yurchenko, Sergei N.; Bernath, Peter; Müller, Holger S. P.; McConkey, Stephanie; Tennyson, Jonathan

    2017-09-01

    Line lists for the X 2Π electronic ground state for the parent isotopologue of nitric oxide (14N16O) and five other major isotopologues (14N17O, 14N18O, 15N16O, 15N17O and 15N18O) are presented. The line lists are constructed using empirical energy levels (and line positions) and high-level ab initio intensities. The energy levels were obtained using a combination of two approaches, from an effective Hamiltonian and from solving the rovibronic Schrödinger equation variationally. The effective Hamiltonian model was obtained through a fit to the experimental line positions of NO available in the literature for all six isotopologues using the programs spfit and spcat. The variational model was built through a least squares fit of the ab initio potential and spin-orbit curves to the experimentally derived energies and experimental line positions of the main isotopologue only using the duo program. The ab initio potential energy, spin-orbit and dipole moment curves (PEC, SOC and DMC) are computed using high-level ab initio methods and the marvel method is used to obtain energies of NO from experimental transition frequencies. The line lists are constructed for each isotopologue based on the use of the most accurate energy levels and the ab initio DMC. Each line list covers a wavenumber range from 0 to 40 000 cm-1 with approximately 22 000 rovibronic states and 2.3-2.6 million transitions extending to Jmax = 184.5 and vmax = 51. Partition functions are also calculated up to a temperature of 5000 K. The calculated absorption line intensities at 296 K using these line lists show excellent agreement with those included in the HITRAN and HITEMP data bases. The computed NO line lists are the most comprehensive to date, covering a wider wavenumber and temperature range compared to both the HITRAN and HITEMP data bases. These line lists are also more accurate than those used in HITEMP. The full line lists are available from the CDS http://cdsarc.u-strasbg.fr and ExoMol www

  13. Lexical Variation in Akokoid

    Directory of Open Access Journals (Sweden)

    Fádorò Jacob Oludare

    2014-07-01

    Full Text Available Language contact among Akokoid, Yoruboid and Edoid has resulted in extensive borrowing from Yoruboid and Edoid to Akokoid. Thus, the speech forms subsumed under Akokoid exhibit lexical items which are similar to Yoruboid and Edoid. To the best of our knowledge, no other scholarly work has addressed the concept ‘lexical variation in these speech forms, hence, the need for this present effort. Twenty lexical items were carefully selected for analysis in this paper. Data were elicited from 34 informants who are competent speakers of Akokoid. Apart from the linguistic data, these informants, including  traditional rulers, supplied us with historical facts about the migration patterns of the progenitors of Akokoid. The historical facts coupled with the linguistic data helped us to arrive at the conclusion that some of the words used in contemporary Akokoid found their way into Akokoid as a result of the contact between Akokoid and their neighbours, Yoruboid and Edoid.

  14. On-line Measurements of Settling Charateristics in Activated Sludge

    DEFF Research Database (Denmark)

    Rasmussen, Michael R.; Larsen, Torben

    1997-01-01

    An on-line settling column for measuring the dynamic variations of settling velocity of activated sludge has been developed. The settling column is automatic and self-cleansing insuring continuous and reliable measurements. The settling column was tested on sludge from a batch reactor where sucrose...... was added as an impulse to activated sludge. The continuous measurement of settling velocity revealed a highly dynamic response after the sucrose was added. The result were verified with simultaneous measurement of the initial settling rate. A 200 hour experiment showed variations in settling velocity......, which was not apparent in the DSVI (Diluted Sludge Volume Index)....

  15. Cool Season Paleotemperatures at Tree Line in Taiwan

    Science.gov (United States)

    Wright, W. E.; Chan, M.

    2011-12-01

    Taiwan has over 200 mountains whose peaks exceed 3,000 meters in elevation. Despite straddling the Tropic of Cancer, the higher peaks have snow and freezing temperatures every winter. Trees growing above 3,500 meters show clear temperature variation, even producing frost rings. Yet unlike temperate tree-line species, with their warm season temperature signal, trees growing at Taiwan's tree line show sensitivity to cool season temperatures. Juniperus squamata growing above 3,500 meters in central Taiwan have ring width time series that commonly exceed 600 years. Presented are the first dendroclimatological analyses from Taiwanese Juniperus squamata.

  16. A universal mammalian vaccine cell line substrate.

    Directory of Open Access Journals (Sweden)

    Jackelyn Murray

    Full Text Available Using genome-wide small interfering RNA (siRNA screens for poliovirus, influenza A virus and rotavirus, we validated the top 6 gene hits PV, RV or IAV to search for host genes that when knocked-down (KD enhanced virus permissiveness and replication over wild type Vero cells or HEp-2 cells. The enhanced virus replication was tested for 12 viruses and ranged from 2-fold to >1000-fold. There were variations in virus-specific replication (strain differences across the cell lines examined. Some host genes (CNTD2, COQ9, GCGR, NDUFA9, NEU2, PYCR1, SEC16G, SVOPL, ZFYVE9, and ZNF205 showed that KD resulted in enhanced virus replication. These findings advance platform-enabling vaccine technology, the creation of diagnostic cells substrates, and are informative about the host mechanisms that affect virus replication in mammalian cells.

  17. Fractions, Number Lines, Third Graders

    Science.gov (United States)

    Cramer, Kathleen; Ahrendt, Sue; Monson, Debra; Wyberg, Terry; Colum, Karen

    2017-01-01

    The Common Core State Standards for Mathematics (CCSSM) (CCSSI 2010) outlines ambitious goals for fraction learning, starting in third grade, that include the use of the number line model. Understanding and constructing fractions on a number line are particularly complex tasks. The current work of the authors centers on ways to successfully…

  18. Marine line fish research programme

    CSIR Research Space (South Africa)

    SANCOR

    1979-04-01

    Full Text Available This report outlines the framework for a marine line fish programme under the aegis of the South African National Committee for Oceanographic Research (SANCOR). An attempt is made to assess the state of knowledge about South African marine line...

  19. relline: Relativistic line profiles calculation

    Science.gov (United States)

    Dauser, Thomas

    2015-05-01

    relline calculates relativistic line profiles; it is compatible with the common X-ray data analysis software XSPEC (ascl:9910.005) and ISIS (ascl:1302.002). The two basic forms are an additive line model (RELLINE) and a convolution model to calculate relativistic smearing (RELCONV).

  20. Drops, contact lines, and electrowetting

    NARCIS (Netherlands)

    't Mannetje, Dieter

    2013-01-01

    In this work, we study the behaviour of drops and contact lines under the influence of electric fields, and how these can answer fundamental and industrial questions. Our focus is on studying the varying balance of the electric field, hysteresis forces and inertia as the speed of a contact line

  1. A transmission line phase stabilizer

    Science.gov (United States)

    Lutes, G. F.

    1979-01-01

    To meet the phase stability requirements of certain experiments performed with the Deep Space Network, transmission lines carrying reference signals must be stabilized to reduce changes in their electrical length due to mechanical movement or changes in ambient temperature. A transmission line phase stabilizer being developed at JPL to perform this function is described.

  2. What was the Assembly Line?

    DEFF Research Database (Denmark)

    Nye, David

    2010-01-01

    The assembly line is still evolving a century after its invention, and it was not a distinct historical stage, nor was it part of an inevitable sequence that followed "Taylorism."......The assembly line is still evolving a century after its invention, and it was not a distinct historical stage, nor was it part of an inevitable sequence that followed "Taylorism."...

  3. US line-ups outperform UK line-ups.

    Science.gov (United States)

    Seale-Carlisle, Travis M; Mickes, Laura

    2016-09-01

    In the USA and the UK, many thousands of police suspects are identified by eyewitnesses every year. Unfortunately, many of those suspects are innocent, which becomes evident when they are exonerated by DNA testing, often after having been imprisoned for years. It is, therefore, imperative to use identification procedures that best enable eyewitnesses to discriminate innocent from guilty suspects. Although police investigators in both countries often administer line-up procedures, the details of how line-ups are presented are quite different and an important direct comparison has yet to be conducted. We investigated whether these two line-up procedures differ in terms of (i) discriminability (using receiver operating characteristic analysis) and (ii) reliability (using confidence-accuracy characteristic analysis). A total of 2249 participants watched a video of a crime and were later tested using either a six-person simultaneous photo line-up procedure (USA) or a nine-person sequential video line-up procedure (UK). US line-up procedure yielded significantly higher discriminability and significantly higher reliability. The results do not pinpoint the reason for the observed difference between the two procedures, but they do suggest that there is much room for improvement with the UK line-up.

  4. Fibrillary lines in overnight orthokeratology.

    Science.gov (United States)

    Lum, Edward; Swarbrick, Helen

    2007-07-01

    This case report describes the appearance of fibrillary lines in the anterior stroma of a 39-year-old Asian woman wearing overnight orthokeratology (OK) lenses. The fibrillary lines were fine, slightly curved and sub-epithelial, arranged in a band-like annulus in the corneal mid-periphery. The lines were not associated with epithelial staining, although a marked Fischer-Schweitzer corneal mosaic was noted after blinking. Fibrillary lines are a relatively common finding in normal and keratoconic corneas and have been reported previously accompanying OK lens wear. Their origin is unknown and epithelial neural remodelling, corneal biomechanical stress and abrupt corneal curvature changes have been suggested as contributing factors. The appearance of fibrillary lines in our OK patient had no adverse consequences on vision or ocular health, at least in the medium term.

  5. Formación on line On line learning

    Directory of Open Access Journals (Sweden)

    O. Grau-Perejoan

    2008-09-01

    Full Text Available La formación on line es una modalidad de enseñanza a distancia basada en las nuevas tecnologías. En este artículo se pretende hacer una introducción a base de describir a grandes rasgos sus características principales: asincronía, no presencialidad, comunicación escrita, función del profesor on line, así como los retos, los riesgos, las ventajas y los inconvenientes que plantea. Se exponen las diferencias entre la formación on line y la formación presencial, de manera que los docentes puedan adaptar de la mejor manera posible sus propuestas formativas a la modalidad on line. Se introduce el importantísimo papel de la planificación y de la fase de diseño y, finalmente, se repasan conceptos útiles para comprender mejor el mundo de la formación on line como son los conceptos entorno virtual de aprendizaje (EVA o Blended Learning (B-Learning.On line learning is a type of distance education based on new technologies. This article's aim is to introduce its main characteristics -asynchrony, non-presentiality, written communication, e-teacher role- as well as its challenges, risks, advantages and limitations. Differences between on line learning and face-to-face learning are presented in order to enable educational professionals to adapt their courses to the on line methodology. Planning and designing are introduced as key phases and, finally, useful concepts such as Virtual Learning Environment (VLE or Blended Learning (B-Learning are reviewed in order to achieve a better understanding of the on line learning field.

  6. Cyclotron Line Measurements with INTEGRAL

    Science.gov (United States)

    Pottschmidt, K.; Kreykenbohm, I.; Caballero, I.; Fritz, S.; Schoenherr, G.; Kretschmar, P.; Wilms, J.; McBride, V. A.; Suchy, S.; Rothschild, R. E.

    2008-01-01

    Due to its broadband energy coverage, INTEGRAL has made important contributions to observing and interpreting cyclotron lines, which are present in the 10-100 keV range of a sample of accreting pulsars. In these systems photons with energies fulfilling the resonance condition inelastically Compton scatter off electrons quantized in the accretion column above the neutron star's magnetic pole(s). This process gives rise to the broad, absorption-like lines or 'cyclotron resonant scattering features' (CRSF). The observed lines allow to directly measure the B-fields of these sources, resulting in values of a few times 1E12G. In this overview I will present recent highlights regarding CRSF observations as well as discuss current ideas and models for the physical conditions in the accretion column. Among the former are the stability of the spectrum of Vela X-1 during giant flares in 2003, the observation of three cyclotron lines during the 2004 outburst of V0332+53, the confirmation of the fundamental line at approximately 45 keV during a 2005 normal outburst of A0535-26, and the simultaneous detection of the two lines in the dipping source 4U 1907+09 (for which also a torque reversal was detected for the first time). Through these and other observations it has become increasingly apparent that two types of observations can potentially be used to constrain the accretion column geometry: the determination of energy ratios for multiple harmonic lines (only two sources with greater than 2 lines are known), was well as the evolution of the fundamental line centroid, which, for different sources, may or may not be correlated with flux. Furthermore, first steps have been taken away from the usual phenomenological description of the lines, towards a physical approach based on self-consistent CRSF modeling. Initial applications are presented.

  7. FROG - Fingerprinting Genomic Variation Ontology.

    Directory of Open Access Journals (Sweden)

    E Abinaya

    Full Text Available Genetic variations play a crucial role in differential phenotypic outcomes. Given the complexity in establishing this correlation and the enormous data available today, it is imperative to design machine-readable, efficient methods to store, label, search and analyze this data. A semantic approach, FROG: "FingeRprinting Ontology of Genomic variations" is implemented to label variation data, based on its location, function and interactions. FROG has six levels to describe the variation annotation, namely, chromosome, DNA, RNA, protein, variations and interactions. Each level is a conceptual aggregation of logically connected attributes each of which comprises of various properties for the variant. For example, in chromosome level, one of the attributes is location of variation and which has two properties, allosomes or autosomes. Another attribute is variation kind which has four properties, namely, indel, deletion, insertion, substitution. Likewise, there are 48 attributes and 278 properties to capture the variation annotation across six levels. Each property is then assigned a bit score which in turn leads to generation of a binary fingerprint based on the combination of these properties (mostly taken from existing variation ontologies. FROG is a novel and unique method designed for the purpose of labeling the entire variation data generated till date for efficient storage, search and analysis. A web-based platform is designed as a test case for users to navigate sample datasets and generate fingerprints. The platform is available at http://ab-openlab.csir.res.in/frog.

  8. Research Into a Neon Spectral Line Profile of Dusty Plasma

    CERN Document Server

    Pikalev, Aleksandr

    2014-01-01

    Ordered dusty structures influence plasma conditions. This influence can be revealed, when plasma spectral characteristics change, as dusty particles are injected. For example, a variation in the atomic temperature leads to a variation in the profiles of spectral lines. We studied the profile of a 585 nm neon spectral line in the dusty structures. The structures levitated in a positive column of a glow discharge at a pressure of 50-150 Pa and with a current of 1-9 mA. We scanned the profile with the use of a Fabry-Perot interferometer, by changing the air pressure between the interferometer mirrors. To process the data, a special algorithm was developed. The algorithm is resistant to a noise and a scanning speed instability. We have found an upper bound of the impact of dusty structures on the profile width. The appearance of macroparticles changes the atomic plasma temperature less than by 10 K.

  9. Teaching Braille Line Tracking Using Stimulus Fading

    Science.gov (United States)

    Scheithauer, Mindy C.; Tiger, Jeffrey H.

    2014-01-01

    Line tracking is a prerequisite skill for braille literacy that involves moving one's finger horizontally across a line of braille text and identifying when a line ends so the reader may reset his or her finger on the subsequent line. Current procedures for teaching line tracking are incomplete, because they focus on tracking lines with only…

  10. Selecting winter wheat lines from a composite cross population

    OpenAIRE

    Fradgley, Nick; Wolfe, Martin; Howlett, Sally; Creissen, Henry; Girling, Robbie

    2014-01-01

    The extremely diverse genetic variation in wheat Composite Cross Populations (CCP) represents a valuable source of breeding material. Such material could be selected as part of a participatory breeding programme with the potential advantage of selecting adaptation targeted for particular environments. For example, selections could be made aimed at producing lines that would thrive under the wide range of management practices conducted as part of organic and low input farming systems. Ear...

  11. Tunable optical delay line for optical time-division multiplexer

    Science.gov (United States)

    Yu, Zhihua; Zhang, Qi; Wang, Hong; Zhang, Jingjing; Selviah, David R.

    2017-07-01

    A novel three-stage all-pass filter (APF) is proposed as a tunable optical delay line to construct an optical time division multiplexer (OTDM), with which, we can get ultrahigh bit rates with several low-speed channels. The proposed design mitigates the deleterious effects of group delay dispersion and provides wide bandwidth with small ripples and continuously tunable long delays achieved with small variations in the effective refraction index, making it suitable for high-speed optical networks on chip.

  12. Variation, "evolution", immortality and genetic instabilities in tumour cells.

    Science.gov (United States)

    Bignold, L P

    2007-08-18

    The pathological characteristics of tumour cells often include variation of their histopathological features (i.e. "degrees of de-differentiation") between cases of the same tumour type and between different foci within individual tumours. Usually, only a few cell lines from tumours are immortal. Currently, somatic mutation, replicative infidelity of DNA and aneuploidy are suggested as alternative mechanisms of genomic disturbance underlying tumours. Nevertheless, apart from Hansemann's ideas of "anaplasia" and "de-differentiation" (proposed in the 1890s), and supposed "evolutionary themes" in cancer cell biology, little has been published concerning how histopathologic variation and immortality in tumour cells might arise. This paper reviews applications of the concepts of "variation" to tumours, including concepts of "evolution" and "cellular Darwinism". It is proposed that combinations of somatic mutation, DNA replicative infidelity and aneuploidy may explain the variabilities in tumours, and provide immortality in occasional tumour cells. A possible model involves (i) an initial somatic mutation causing reduced replicative fidelity of DNA, which could be variable in intensity, and thus give rise to variations between cases; (ii) a phase of replicative infidelity of DNA causing daughter cells lines to develop various abnormalities to different degrees, and hence provide for variation between areas of the same tumour. As a last event (iii) occasional asymmetric chromosomal distributions (aneuploidy) might "refresh" the ability of a daughter cell to replicate DNA faithfully causing them to become immortal. Thus extensively mutant and variable, hyperploid, and occasionally immortal cells might arise.

  13. Atlas transmission line breakdown analysis

    CERN Document Server

    Nielsen, K E; Ballard, E O; Elizondo, J M; Gribble, R F; McCuistian, B T; Parsons, W M

    1999-01-01

    The Atlas facility will use 24 radially converging, vertically oriented and tapered, oil insulated, triplate transmission lines between the Marx generators and the central load region. Among the requirements of the transmission lines are low inductance and high reliability. The inter-conductor gap is nominally 2 cm and the lines taper from a height of 1.75 m at the Marx end to 0.32 m at the output end. The aluminum conductors, held together by 20 insulating spacers, are assembled and inserted as a unit into radial oil-filled steel tanks. The negative, high-voltage, center conductor is 2.54-cm thick and the outer ground conductors are 1.59-cm thick. All 24 triplate transmission lines connect to a transition section at near 1 m radius that couples the transmission lines to a disk/conical solid- dielectric-insulated power flow channel transmission line terminating at the load. Peak operating voltage on the lines can be as high as 240 kV with an effective stress time of 0.8 mu s. Testing of small sections of the ...

  14. Transmission-Line Metamaterials, Bianisotropy, and Transmission-Line Bianisotropy

    OpenAIRE

    Vehmas, Joni

    2015-01-01

    Electromagnetic metamaterials are artificial composite materials which possess exotic and advantageous properties not attainable with natural materials. This thesis covers two notable classes of metamaterials: transmission-line metamaterials and bianisotropic media. While metamaterials are most commonly realized as bulk media consisting of small resonant inclusions, transmission-line structures offer an alternative, low-dispersion and low-loss way for realizing them. Bianisotropic media, on t...

  15. On the Total Variation Distance of Semi-Markov Chains

    DEFF Research Database (Denmark)

    Bacci, Giorgio; Bacci, Giovanni; Larsen, Kim Guldstrand

    2015-01-01

    Semi-Markov chains (SMCs) are continuous-time probabilistic transition systems where the residence time on states is governed by generic distributions on the positive real line. This paper shows the tight relation between the total variation distance on SMCs and their model checking problem over...... linear real-time specifications. Specifically, we prove that the total variation between two SMCs coincides with the maximal difference w.r.t. the likelihood of satisfying arbitrary MTL formulas or omega-languages recognized by timed automata. Computing this distance (i.e., solving its threshold problem...

  16. Comprehensive CFD simulation of the ladle cycle toward lining service life optimization

    Science.gov (United States)

    Al-Harbi, Mansour; Al-Nefai, Abdullah; Al-Jarallah, Sami; Al-Dossary, Abdullah; Jagan, Yannam

    2012-07-01

    The objective of this study is to optimize ladle cycle to enhance the lining service life. This optimization would be achieved by a better understanding of the lining thermal conditions during the varies stages of the ladle cycle by a mathematical simulation of the process. A 2D axisymmetric mathematical model was developed to predict the ladle lining and steel shell temperature during the full ladle cycle. The estimated steel shell temperature during drying and preheating process of a newly lined ladle was in good agreement with the literature and the plant expectation. This study recommend to make some changes in the current ladle cycle practice to reduce the abnormal lining temperature variation. Also recommend to enhance the preheating burners for sufficient lining drying/preheating. This then would improve the lining service life and reduce the refractory consumptions rate.

  17. Structure related phylogenetic variations in brain gangliosides of vertebrates.

    Science.gov (United States)

    Hilbig, R

    1984-01-01

    The concentration and composition of brain gangliosides from five brain structures of vertebrate species belonging to the classes of Chondrichthyes, Osteichthyes, Reptilia, Aves and Mammalia were investigated. The complexity of brain ganglioside composition is strikingly reduced over phyletic lines. In lower vertebrates there is only little variation in the ganglioside pattern between the different brain structures, whereas in higher vertebrates differences distinctly occurred. A similarity over phyletic lines of ganglioside pattern was only noted in phylogenetically old brain structures as for instance in the medulla oblongata and the brain stem.

  18. Cluster-based exposure variation analysis

    Science.gov (United States)

    2013-01-01

    Background Static posture, repetitive movements and lack of physical variation are known risk factors for work-related musculoskeletal disorders, and thus needs to be properly assessed in occupational studies. The aims of this study were (i) to investigate the effectiveness of a conventional exposure variation analysis (EVA) in discriminating exposure time lines and (ii) to compare it with a new cluster-based method for analysis of exposure variation. Methods For this purpose, we simulated a repeated cyclic exposure varying within each cycle between “low” and “high” exposure levels in a “near” or “far” range, and with “low” or “high” velocities (exposure change rates). The duration of each cycle was also manipulated by selecting a “small” or “large” standard deviation of the cycle time. Theses parameters reflected three dimensions of exposure variation, i.e. range, frequency and temporal similarity. Each simulation trace included two realizations of 100 concatenated cycles with either low (ρ = 0.1), medium (ρ = 0.5) or high (ρ = 0.9) correlation between the realizations. These traces were analyzed by conventional EVA, and a novel cluster-based EVA (C-EVA). Principal component analysis (PCA) was applied on the marginal distributions of 1) the EVA of each of the realizations (univariate approach), 2) a combination of the EVA of both realizations (multivariate approach) and 3) C-EVA. The least number of principal components describing more than 90% of variability in each case was selected and the projection of marginal distributions along the selected principal component was calculated. A linear classifier was then applied to these projections to discriminate between the simulated exposure patterns, and the accuracy of classified realizations was determined. Results C-EVA classified exposures more correctly than univariate and multivariate EVA approaches; classification accuracy was 49%, 47% and 52% for EVA (univariate

  19. Pulse shaping with transmission lines

    Science.gov (United States)

    Wilcox, Russell B.

    1987-01-01

    A method and apparatus for forming shaped voltage pulses uses passive reflection from a transmission line with nonuniform impedance. The impedance of the reflecting line varies with length in accordance with the desired pulse shape. A high voltage input pulse is transmitted to the reflecting line. A reflected pulse is produced having the desired shape and is transmitted by pulse removal means to a load. Light activated photoconductive switches made of silicon can be utilized. The pulse shaper can be used to drive a Pockels cell to produce shaped optical pulses.

  20. The infinite line pressure probe

    Science.gov (United States)

    Englund, D. R.; Richards, W. B.

    1985-01-01

    The infinite line pressure probe provides a means for measuring high frequency fluctuating pressures in difficult environments. A properly designed infinite line probe does not resonate; thus its frequency response is not limited by acoustic resonance in the probe tubing, as in conventional probes. The characteristics of infinite line pressure probes are reviewed and some applications in turbine engine research are described. A probe with a flat-oval cross section, permitting a constant-impedance pressure transducer installation, is described. Techniques for predicting the frequency response of probes with both circular and flat-oval cross sections are also cited.

  1. Electrical transmission line diametrical retainer

    Science.gov (United States)

    Hall, David R.; Hall, Jr., H. Tracy; Pixton, David; Dahlgren, Scott; Sneddon, Cameron; Briscoe, Michael; Fox, Joe

    2004-12-14

    The invention is a mechanism for retaining an electrical transmission line. In one embodiment of the invention it is a system for retaining an electrical transmission line within down hole components. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string. The system also includes a coaxial cable running between the first and second end of a drill pipe, the coaxial cable having a conductive tube and a conductive core within it. The invention allows the electrical transmission line to with stand the tension and compression of drill pipe during routine drilling cycles.

  2. Explorations in Regional Variation: A Variational Pragmatic Perspective

    Science.gov (United States)

    Barron, Anne

    2015-01-01

    The present article introduces the Special Issue entitled "A Variational Pragmatic Approach to Regional Variation in Language," a collection of papers which celebrates the work of Klaus P. Schneider (Rheinische Friedrich-Wilhelms-Universität Bonn, Germany) on the occasion of his 60th birthday.

  3. In-situ Blockage Monitoring of Sensing Line

    Directory of Open Access Journals (Sweden)

    Aijaz Ahmed Mangi

    2016-02-01

    Full Text Available A reactor vessel level monitoring system measures the water level in a reactor during normal operation and abnormal conditions. A drop in the water level can expose nuclear fuel, which may lead to fuel meltdown and radiation spread in accident conditions. A level monitoring system mainly consists of a sensing line and pressure transmitter. Over a period of time boron sediments or other impurities can clog the line which may degrade the accuracy of the monitoring system. The aim of this study is to determine blockage in a sensing line using the energy of the composite signal. An equivalent Pi circuit model is used to simulate blockages in the sensing line and the system's response is examined under different blockage levels. Composite signals obtained from the model and plant's unblocked and blocked channels are decomposed into six levels of details and approximations using a wavelet filter bank. The percentage of energy is calculated at each level for approximations. It is observed that the percentage of energy reduces as the blockage level in the sensing line increases. The results of the model and operational data are well correlated. Thus, in our opinion variation in the energy levels of approximations can be used as an index to determine the presence and degree of blockage in a sensing line.

  4. Non-LTE profiles of the Al I autoionization lines. [for solar model atmospheres

    Science.gov (United States)

    Finn, G. D.; Jefferies, J. T.

    1974-01-01

    A non-LTE formulation is given for the transfer of radiation in the autoionizing lines of neutral aluminum at 1932 and 1936 A through both the Bilderberg and Harvard-Smithsonian model atmospheres. Numerical solutions for the common source function of these lines and their theoretical line profiles are calculated and compared with the corresponding LTE profiles. The results show that the non-LTE profiles provide a better match with the observations. They also indicate that the continuous opacity of the standard solar models should be increased in this wavelength region if the center-limb variations of observed and theoretical profiles of these lines are to be in reasonable agreement.

  5. VT Senate Districts 1992 - lines

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The senatorial district designations for this layer were taken from a trace map of unknown origin. A visual compilation of the traced lines and...

  6. Louisiana ESI: ROADS (Road Lines)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains the state maintained primary and secondary road network of Louisiana. Vector lines in the data set represent Interstates, U.S. Highways, and...

  7. Horizontal and Vertical Line Designs.

    Science.gov (United States)

    Johns, Pat

    2003-01-01

    Presents an art lesson in which students learn about the artist Piet Mondrian and create their own abstract artworks. Focuses on geometric shapes using horizontal and vertical lines. Includes background information about the artist. (CMK)

  8. Digital Line Graph - Large Scale

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Digital line graph (DLG) data are digital representations of cartographic information. DLGs of map features are converted to digital form from maps and related...

  9. Composite Materials in Overhead Lines

    DEFF Research Database (Denmark)

    Sørensen, Thomas Kjærsgaard; Holbøll, Joachim

    2009-01-01

    The use of composite materials, e.g. fibreglass materials, in overhead transmission line systems is nothing new. Composite based insulators have been applied to transmission lines for over 30 years, mainly as suspension and post insulators and often as an option for special applications. Also...... towers and recently conductors based on composite materials are available at transmission levels. In this paper it is investigated which composite based solutions are available in connection with complete overhead line systems including insulators, towers and conductors. The components are reviewed...... with respect to solved and persisting known failures/problems of both mechanical and electrical nature. Major challenges related to extensive use of composite materials in an overhead line system are identified, as are possible benefits - both when using standard as well as customised composite components, e...

  10. Umbilic Lines in Orientational Order

    Directory of Open Access Journals (Sweden)

    Thomas Machon

    2016-03-01

    Full Text Available Three-dimensional orientational order in systems whose ground states possess nonzero gradients typically exhibits linelike structures or defects: λ lines in cholesterics or Skyrmion tubes in ferromagnets, for example. Here, we show that such lines can be identified as a set of natural geometric singularities in a unit vector field, the generalization of the umbilic points of a surface. We characterize these lines in terms of the natural vector bundles that the order defines and show that they give a way to localize and identify Skyrmion distortions in chiral materials—in particular, that they supply a natural representative of the Poincaré dual of the cocycle describing the topology. Their global structure leads to the definition of a self-linking number and helicity integral which relates the linking of umbilic lines to the Hopf invariant of the texture.

  11. Control Point Generated PLS - lines

    Data.gov (United States)

    Minnesota Department of Natural Resources — The Control Point Generated PLS layer contains line and polygon features to the 1/4 of 1/4 PLS section (approximately 40 acres) and government lot level. The layer...

  12. Fractional Transmission Line with Losses

    Science.gov (United States)

    Gómez-Aguilar, José Francisco; Dumitru, Baleanu

    2014-11-01

    In this manuscript, the fractional transmission line with losses is presented. The order of the Caputo derivative is considered as 0 Mittag-Leffler functions. The classic cases are recovered when β and γ are equal to 1.

  13. Program of telluric lines monitoring

    Directory of Open Access Journals (Sweden)

    Vince I.

    2006-01-01

    Full Text Available A new observational program of telluric lines monitoring was introduced at Belgrade Astronomical Observatory. The ultimate goal of this program is to investigate the properties of Earth’s atmosphere through modeling the observed profiles of telluric lines. The program is intend to observe infrared molecular oxygen lines that were selected according to spectral sensitivity of the available CCD camera. In this paper we give the initial and the final selection criteria for spectral lines included in the program the description of equipment and procedures used for observations and reduction, a review of preliminary observational results with the estimated precision, and a short discussion on the comparison of the theoretical predictions and the measurements.

  14. Transmission line model for nanoelectronics

    Directory of Open Access Journals (Sweden)

    Nelin E. A.

    2009-08-01

    Full Text Available Analytical expressions for resonant parametres and characteristics of typical barrier nanoelectronic structures have been received on the basis of the transmission line model. Characteristics illustrating the efficiency of such approach are presented in the article.

  15. Railroad Lines, US, 2015, NAVTEQ

    Data.gov (United States)

    U.S. Environmental Protection Agency — NAVTEQ Railroads for the United States. The Railroads layer contains Railroad features published as lines and polylines. Attributes for this layer include the name...

  16. Base Flood Elevation (BFE) Lines

    Data.gov (United States)

    Department of Homeland Security — The Base Flood Elevation (BFE) table is required for any digital data where BFE lines will be shown on the corresponding Flood Insurance Rate Map (FIRM). Normally if...

  17. Radio and line transmission 2

    CERN Document Server

    Roddy, Dermot

    2013-01-01

    Radio and Line Transmission, Volume 2 gives a detailed treatment of the subject as well as an introduction to additional advanced subject matter. Organized into 14 chapters, this book begins by explaining the radio wave propagation, signal frequencies, and bandwidth. Subsequent chapters describe the transmission lines and cables; the aerials; tuned and coupled circuits; bipolar transistor amplifiers; field-effect transistors and circuits; thermionic valve amplifiers; LC oscillators; the diode detectors and modulators; and the superheterodyne receiver. Other chapters explore noise and interfere

  18. ESR powder line shape calculations

    Energy Technology Data Exchange (ETDEWEB)

    Vitko, J. Jr.; Huddleston, R.E.

    1976-05-01

    A program has been developed for computing the ESR spectrum of a collection of randomly oriented spins subject only to an electronic Zeeman interaction and having a Lorentzian single crystal line shape. Other single crystal line shapes, including numerical solutions of the Bloch equations, can be accommodated with minor modifications. The program differs in several features from those existing elsewhere, thus enabling one to study saturation effects, over-modulation effects, both absorptive and dispersive signals, and second and higher order derivative signals.

  19. Maria Reiche's Line to Archaeoastronomy

    OpenAIRE

    Sparavigna, Amelia Carolina

    2013-01-01

    Maria Reiche was a German mathematician and archaeologist that, from 1940, devoted her life to the study of the Nazca Lines, the most famous Peruvian geoglyphs, gaining recognition and preservation of them. Created by removing the upper most layer of the arid soil of the Nazca desert, these geoglyphs, declared in 1995 a UNESCO World Heritage Site, are composed by very long straight and trapezoidal lines, spirals and large figures representing animals. Maria Reiche, in fact an archaeoastronome...

  20. Double helix nodal line superconductor

    OpenAIRE

    Sun, Xiao-Qi; Lian, Biao; Zhang, Shou-Cheng

    2017-01-01

    Time-reversal invariant superconductors in three dimensions may contain nodal lines in the Brillouin zone, which behave exactly as Wilson loops of 3d momentum-space Chern-Simons theory of the Berry connection. Here we study the conditions of realizing linked nodal lines (Wilson loops), which yield a topological contribution to the thermal magnetoelectric coefficient that is given by the Chern-Simons action. We find the essential conditions are the existence of torus or higher genus fermi surf...

  1. Electron Stark Broadening Database for Atomic N, O, and C Lines

    Science.gov (United States)

    Liu, Yen; Yao, Winifred M.; Wray, Alan A.; Carbon, Duane F.

    2012-01-01

    A database for efficiently computing the electron Stark broadening line widths for atomic N, O, and C lines is constructed. The line width is expressed in terms of the electron number density and electronatom scattering cross sections based on the Baranger impact theory. The state-to-state cross sections are computed using the semiclassical approximation, in which the atom is treated quantum mechanically whereas the motion of the free electron follows a classical trajectory. These state-to-state cross sections are calculated based on newly compiled line lists. Each atomic line list consists of a careful merger of NIST, Vanderbilt, and TOPbase line datasets from wavelength 50 nm to 50 micrometers covering the VUV to IR spectral regions. There are over 10,000 lines in each atomic line list. The widths for each line are computed at 13 electron temperatures between 1,000 K 50,000 K. A linear least squares method using a four-term fractional power series is then employed to obtain an analytical fit for each line-width variation as a function of the electron temperature. The maximum L2 error of the analytic fits for all lines in our line lists is about 5%.

  2. On quadratic variation of martingales

    Indian Academy of Sciences (India)

    Doob–Meyer decomposition; martingales; quadratic variation. Mathematics Subject Classification. ... t also the predictable quadratic variation of the martingale. M and has subsequently been ...... [3] Karandikar R L, Pathwise solution of stochastic differential equations, Sankhya A 43. (1981) 121–132. [4] Karandikar R L, On ...

  3. Exploring language variation across Europe

    DEFF Research Database (Denmark)

    Hovy, Dirk; Johannsen, Anders Trærup

    2016-01-01

    training in both variational linguistics and computational methods, a combination that is still not common. We take a first step here to alleviate the problem by providing an interface to explore large-scale language variation along several socio-demographic factors without programming knowledge. It makes...

  4. Biological variation of cystatin C

    DEFF Research Database (Denmark)

    Reinhard, Mark; Erlandsen, Erland; Randers, Else

    2009-01-01

    Introduction: Cystatin C has been investigated as a marker of the glomerular filtration rate. However, previous studies have reported conflicting results concerning the biological variation of cystatin C. The aim of the present study was to evaluate the biological variation of cystatin C...

  5. Line-by-line spectroscopic simulations on graphics processing units

    Science.gov (United States)

    Collange, Sylvain; Daumas, Marc; Defour, David

    2008-01-01

    We report here on software that performs line-by-line spectroscopic simulations on gases. Elaborate models (such as narrow band and correlated-K) are accurate and efficient for bands where various components are not simultaneously and significantly active. Line-by-line is probably the most accurate model in the infrared for blends of gases that contain high proportions of H 2O and CO 2 as this was the case for our prototype simulation. Our implementation on graphics processing units sustains a speedup close to 330 on computation-intensive tasks and 12 on memory intensive tasks compared to implementations on one core of high-end processors. This speedup is due to data parallelism, efficient memory access for specific patterns and some dedicated hardware operators only available in graphics processing units. It is obtained leaving most of processor resources available and it would scale linearly with the number of graphics processing units in parallel machines. Line-by-line simulation coupled with simulation of fluid dynamics was long believed to be economically intractable but our work shows that it could be done with some affordable additional resources compared to what is necessary to perform simulations on fluid dynamics alone. Program summaryProgram title: GPU4RE Catalogue identifier: ADZY_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADZY_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 62 776 No. of bytes in distributed program, including test data, etc.: 1 513 247 Distribution format: tar.gz Programming language: C++ Computer: x86 PC Operating system: Linux, Microsoft Windows. Compilation requires either gcc/g++ under Linux or Visual C++ 2003/2005 and Cygwin under Windows. It has been tested using gcc 4.1.2 under Ubuntu Linux 7.04 and using Visual C

  6. Towards Perfect Water Line Intensities

    Science.gov (United States)

    Lodi, L.; Tennyson, J.

    2012-06-01

    Over the last ten years the increased availability of computational resources and the steady refinement of theoretical methods have permitted more and more accurate first principle calculations of water-vapor spectra as exemplified, e.g., by the very successful BT2 line list both line positions and intensities, a reliable dipole moment surface (DMS), affecting line intensities. It is also very useful to several application to give reasonable uncertainty bars for computed quantities, an aspect which traditionally has received little attention. We report here recent progress leading to very accurate room-temperature linelists covering the range 0.05-20 000 cm-1, complete with uncertainty bars, for the H_218O and H_217O water isotopologues Line intensities were produced using a recent DMS produced by our group which is capable of giving line intensites accurate to 1% for most medium and strong transitions. Line positions are based if possible on the experimentally derived energy levels recently produced by a IUPAC task group and have a typical accuracy of 0.0002 cm-1; when experimentally derived energy levels are unavailable calculated line position are provided, with an accuracy of the order of 0.2 cm-1. An extension to the main isotopologue H_216O is currently underway. R. J. Barber, J. Tennyson, G. J. Harris and R. N. Tolchenov, Mon. Not. R. Astron. Soc. {368}, 1087-1094 (2006). L. Lodi and J. Tennyson, J. Quant. Spectrosc. Radiat. Trans. (2012), doi:10.1016/j.jqsrt.2012.02.023 L. Lodi, J. Tennyson and O. L. Polyansky, J. Chem. Phys. {135}, 034113 (2011). J. Tennyson at al., J. Quant. Spectrosc. Radiat. Trans. {110}, 573-96 (2009).

  7. Enhanced incoherent scatter plasma lines

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    Full Text Available Detailed model calculations of auroral secondary and photoelectron distributions for varying conditions have been used to calculate the theoretical enhancement of incoherent scatter plasma lines. These calculations are compared with EISCAT UHF radar measurements of enhanced plasma lines from both the E and F regions, and published EISCAT VHF radar measurements. The agreement between the calculated and observed plasma line enhancements is good. The enhancement from the superthermal distribution can explain even the very strong enhancements observed in the auroral E region during aurora, as previously shown by Kirkwood et al. The model calculations are used to predict the range of conditions when enhanced plasma lines will be seen with the existing high-latitude incoherent scatter radars, including the new EISCAT Svalbard radar. It is found that the detailed structure, i.e. the gradients in the suprathermal distribution, are most important for the plasma line enhancement. The level of superthermal flux affects the enhancement only in the region of low phase energy where the number of thermal electrons is comparable to the number of suprathermal electrons and in the region of high phase energy where the suprathermal fluxes fall to such low levels that their effect becomes small compared to the collision term. To facilitate the use of the predictions for the different radars, the expected signal- to-noise ratios (SNRs for typical plasma line enhancements have been calculated. It is found that the high-frequency radars (Søndre Strømfjord, EISCAT UHF should observe the highest SNR, but only for rather high plasma frequencies. The VHF radars (EISCAT VHF and Svalbard will detect enhanced plasma lines over a wider range of frequencies, but with lower SNR.

  8. NLTE analysis of spectra I : Departures from LTE for A-type stars

    NARCIS (Netherlands)

    Kamp, I.; Monier, R.; Smalley, B.; Wahlgren, G.; Stee, Ph.

    2010-01-01

    A-type stars with their shallow convection zones serve as ideal physics laboratories for stellar atmosphere research. In the absence of large scale mixing, processes such as diffusion, mass loss and accretion leave their characteristic imprint on the chemical composition of the photosphere. This

  9. Calculation of opacities and emissivities for carbon plasmas under NLTE and LTE conditions

    Energy Technology Data Exchange (ETDEWEB)

    Gil, J.M.; Rodriguez, R.; Florido, R.; Rubiano, J.G.; Martel, P. [Las Palmas de Gran Canaria Univ., Dept. de Fisica (Spain); Sauvan, P. [Universidad Nacional de Educacion a Distancia, Dept. de Ingenieria Energetica, Madrid (Spain); Minguez, E. [Madrid Univ. Politecnica, Instituto de Fusion Nuclear-DENIM (Spain)

    2006-06-15

    We calculate different optical properties for carbon plasma in a wide range of temperatures and densities by using ATOM3R-OP code which has been recently developed. In this code we have implemented the rate equations, the Saha equation (for local thermodynamic equilibrium) and the coronal equilibrium model. We have calculated average ionizations, level populations, opacities and emissivities and we focus our study on the identification with our code of coronal equilibrium, non-local thermodynamic equilibrium and local thermodynamic equilibrium regions for this kind of plasma. Moreover, we analyse the differences in the optical properties when they are calculated in non-local thermodynamic equilibrium and local thermodynamic equilibrium. (authors)

  10. Variational principles for stochastic fluid dynamics

    Science.gov (United States)

    Holm, Darryl D.

    2015-01-01

    This paper derives stochastic partial differential equations (SPDEs) for fluid dynamics from a stochastic variational principle (SVP). The paper proceeds by taking variations in the SVP to derive stochastic Stratonovich fluid equations; writing their Itô representation; and then investigating the properties of these stochastic fluid models in comparison with each other, and with the corresponding deterministic fluid models. The circulation properties of the stochastic Stratonovich fluid equations are found to closely mimic those of the deterministic ideal fluid models. As with deterministic ideal flows, motion along the stochastic Stratonovich paths also preserves the helicity of the vortex field lines in incompressible stochastic flows. However, these Stratonovich properties are not apparent in the equivalent Itô representation, because they are disguised by the quadratic covariation drift term arising in the Stratonovich to Itô transformation. This term is a geometric generalization of the quadratic covariation drift term already found for scalar densities in Stratonovich's famous 1966 paper. The paper also derives motion equations for two examples of stochastic geophysical fluid dynamics; namely, the Euler–Boussinesq and quasi-geostropic approximations. PMID:27547083

  11. Genetic variation of contact dermatitis in broilers

    DEFF Research Database (Denmark)

    Ask, Birgitte

    2010-01-01

    left and right scores was lower than 1 (FPD: 0.73 and HB: 0.57), and both left and right FPD and HB must, therefore, be evaluated. High prevalences of FPD, but also HB, were achieved in the field trial, but lower prevalences may be sufficient for genetic evaluations and would be less detrimental......This study aimed to investigate the presence of genetic variation in footpad dermatitis (FPD) and hock burns (HB) and the possibility to genetically select against these. A field trial including 10 commercial broiler lines (n = 102 to 265) was carried out at 2 Dutch farms. Footpad dermatitis and HB...... were subjectively scored at ~4, 5, and 7 wk on a scale from 0 through 5. Genetic parameters were estimated in 2 lines based on a larger data set. The overall agreement of repeated FPD and HB scores was high (0.66 to 0.86) and the scoring system was, therefore, considered reliable. Kendall's tau between...

  12. Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior

    Science.gov (United States)

    Shorter, John; Couch, Charlene; Huang, Wen; Carbone, Mary Anna; Peiffer, Jason; Anholt, Robert R. H.; Mackay, Trudy F. C.

    2015-01-01

    Aggression is an evolutionarily conserved complex behavior essential for survival and the organization of social hierarchies. With the exception of genetic variants associated with bioamine signaling, which have been implicated in aggression in many species, the genetic basis of natural variation in aggression is largely unknown. Drosophila melanogaster is a favorable model system for exploring the genetic basis of natural variation in aggression. Here, we performed genome-wide association analyses using the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel (DGRP) and replicate advanced intercross populations derived from the most and least aggressive DGRP lines. We identified genes that have been previously implicated in aggressive behavior as well as many novel loci, including gustatory receptor 63a (Gr63a), which encodes a subunit of the receptor for CO2, and genes associated with development and function of the nervous system. Although genes from the two association analyses were largely nonoverlapping, they mapped onto a genetic interaction network inferred from an analysis of pairwise epistasis in the DGRP. We used mutations and RNAi knock-down alleles to functionally validate 79% of the candidate genes and 75% of the candidate epistatic interactions tested. Epistasis for aggressive behavior causes cryptic genetic variation in the DGRP that is revealed by changing allele frequencies in the outbred populations derived from extreme DGRP lines. This phenomenon may pertain to other fitness traits and species, with implications for evolution, applied breeding, and human genetics. PMID:26100892

  13. Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior.

    Science.gov (United States)

    Shorter, John; Couch, Charlene; Huang, Wen; Carbone, Mary Anna; Peiffer, Jason; Anholt, Robert R H; Mackay, Trudy F C

    2015-07-07

    Aggression is an evolutionarily conserved complex behavior essential for survival and the organization of social hierarchies. With the exception of genetic variants associated with bioamine signaling, which have been implicated in aggression in many species, the genetic basis of natural variation in aggression is largely unknown. Drosophila melanogaster is a favorable model system for exploring the genetic basis of natural variation in aggression. Here, we performed genome-wide association analyses using the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel (DGRP) and replicate advanced intercross populations derived from the most and least aggressive DGRP lines. We identified genes that have been previously implicated in aggressive behavior as well as many novel loci, including gustatory receptor 63a (Gr63a), which encodes a subunit of the receptor for CO2, and genes associated with development and function of the nervous system. Although genes from the two association analyses were largely nonoverlapping, they mapped onto a genetic interaction network inferred from an analysis of pairwise epistasis in the DGRP. We used mutations and RNAi knock-down alleles to functionally validate 79% of the candidate genes and 75% of the candidate epistatic interactions tested. Epistasis for aggressive behavior causes cryptic genetic variation in the DGRP that is revealed by changing allele frequencies in the outbred populations derived from extreme DGRP lines. This phenomenon may pertain to other fitness traits and species, with implications for evolution, applied breeding, and human genetics.

  14. Extent and structure of intervening absorbers from absorption lines redshifted on quasar emission lines

    Science.gov (United States)

    Bergeron, J.; Boissé, P.

    2017-07-01

    Aims: We wish to study the extent and sub-parsec spatial structure of intervening quasar absorbers, mainly those involving cold neutral and molecular gas. Methods: We have selected quasar absorption systems with high spectral resolution and a good signal-to-noise ratio data, with some of their lines falling on quasar emission features. By investigating the consistency of absorption profiles seen for lines formed either against the quasar continuum source or on the much more extended (Lyα-N v, C iv or Lyβ-O vi) emission line region (ELR), we can probe the extent and structure of the foreground absorber over the extent of the ELR ( 0.3-1 pc). The spatial covering analysis provides constraints on the transverse size of the absorber and thus is complementary to variability or photoionisation modelling studies, which yield information on the absorber size along the line of sight. The methods we used to identify spatial covering or structure effects involve line profile fitting and curve-of-growth analysis. Results: We have detected three absorbers with unambiguous non-uniformity effects in neutral gas. For the extreme case of the Fe I absorber at zabs = 0.45206 towards HE 0001-2340, we derive a coverage factor of the ELR of at most 0.10 and possibly very close to zero; this implies an overall absorber size no larger than 0.06 pc. For the zabs = 2.41837 C I absorber towards QSO J1439+1117, absorption is significantly stronger towards the ELR than towards the continuum source in several C I and C I⋆ velocity components, pointing to spatial variations of their column densities of about a factor of two and to structures at the 100 au-0.1 pc scale. The other systems with firm or possible effects can be described in terms of a partial covering of the ELR, with coverage factors in the range 0.7-1. The overall results for cold neutral absorbers imply a transverse extent of about five times the ELR size or smaller, which is consistent with other known constraints. Although

  15. Genetic variations and normal fetal growth.

    Science.gov (United States)

    Dunger, D B; Petry, C J; Ong, K K

    2006-01-01

    Size at birth is said to be a highly heritable trait, with an estimated 30-70% of the variability a result of genetics. Data from family studies may be confounded, however, by potential interactions between fetal genes and the maternal uterine environment. Overall, the maternal environment tends to restrain fetal growth, and this is most evident in first pregnancies. Restraint of fetal growth appears to be inherited through the maternal line. Potential genetic candidates include the mitochondrial DNA 16189 variant, and common variants of exclusively maternally expressed genes, such as H19, which have been associated with size at birth. Maternal blood glucose levels and blood pressure are also correlated with size at birth, but the degree to which these changes relate to genetic variation in the mother is unclear. Elegant studies in mouse knockout models and rare genetic variants in humans have highlighted the importance of insulin-like growth factor I (IGF-I), IGF-II, insulin and their respective receptors in determining fetal growth. However, data linking common variation in the genes that regulate these proteins and receptors with size at birth are few and inconsistent. Interestingly, common variation in the insulin gene (INS) variable number tandem repeats, which regulates the transcription of insulin and IGF-II, has been associated with size at birth, largely in second and subsequent pregnancies, where maternal restraint is least evident. This suggests that fetal genes, and in particular paternally expressed genes, may have significant effects on fetal growth during pregnancies where maternal restraint of fetal growth is less evident. Copyright 2006 S. Karger AG, Basel.

  16. Variation in genome composition of blue-aleurone wheat.

    Science.gov (United States)

    Burešová, Veronika; Kopecký, David; Bartoš, Jan; Martinek, Petr; Watanabe, Nobuyoshi; Vyhnánek, Tomáš; Doležel, Jaroslav

    2015-02-01

    Different blue-aleurone wheats display major differences in chromosome composition, ranging from disomic chromosome additions, substitutions, single chromosome arm introgressions and chromosome translocation of Thinopyrum ponticum. Anthocyanins are of great importance for human health due to their antioxidant, anti-inflammatory, anti-microbial and anti-cancerogenic potential. In common wheat (Triticum aestivum L.) their content is low. However, elite lines with blue aleurone exhibit significantly increased levels of anthocyanins. These lines carry introgressed chromatin from wild relatives of wheat such as Thinopyrum ponticum and Triticum monococcum. The aim of our study was to characterize genomic constitutions of wheat lines with blue aleurone using genomic and fluorescence in situ hybridization. We used total genomic DNA of Th. ponticum and two repetitive DNA sequences (GAA repeat and the Afa family) as probes to identify individual chromosomes. This enabled precise localization of introgressed Th. ponticum chromatin. Our results revealed large variation in chromosome constitutions of the blue-aleurone wheats. Of 26 analyzed lines, 17 carried an introgression from Th. ponticum; the remaining nine lines presumably carry T. monococcum chromatin undetectable by the methods employed. Of the Th. ponticum introgressions, six different types were present, ranging from a ditelosomic addition (cv. Blue Norco) to a disomic substitution (cv. Blue Baart), substitution of complete (homologous) chromosome arms (line UC66049) and various translocations of distal parts of a chromosome arm(s). Different types of introgressions present support a hypothesis that the introgressions activate the blue aleurone trait present, but inactivated, in common wheat germplasm.

  17. Magnetic Field - Secular Variation of the Total Field Component for the Epoch 2010.0 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer shows lines of equal annual change (secular variation), in the total field intensity of the Earth's magnetic field, derived from the International...

  18. Activity-induced radial velocity variation of M dwarf stars

    DEFF Research Database (Denmark)

    Andersen, Jan Marie; Korhonen, Heidi Helena

    2012-01-01

    that can drown out a planetary signature. Cool, low-mass M dwarf stars can be highly active, which can make detection of potentially habitable planets around these stars difficult. We investigate radial velocity variations caused by different activity (spot) patterns on M dwarf stars in order to determine......Stellar magnetic activity manifests itself in a variety of ways including starspots-cool, dark regions on the stellar surface. Starspots can cause variations ('jitter') in spectral line-profiles which can mimic the radial velocity (RV) variations caused by an orbiting planet, or create RV noise...... the limits of detectability for small planets orbiting active M dwarfs. We report on our progress toward the aim of answering the following questions: What types of spot patterns are realistic for M dwarf stars? What effect will spots have on M dwarf RV measurements? Can jitter from M dwarf spots mimic...

  19. Statistics, Uncertainty, and Transmitted Variation

    Energy Technology Data Exchange (ETDEWEB)

    Wendelberger, Joanne Roth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-05

    The field of Statistics provides methods for modeling and understanding data and making decisions in the presence of uncertainty. When examining response functions, variation present in the input variables will be transmitted via the response function to the output variables. This phenomenon can potentially have significant impacts on the uncertainty associated with results from subsequent analysis. This presentation will examine the concept of transmitted variation, its impact on designed experiments, and a method for identifying and estimating sources of transmitted variation in certain settings.

  20. Antipredator behavior QTL: differences in rainbow trout clonal lines derived from wild and hatchery populations.

    Science.gov (United States)

    Christensen, Kris A; Brunelli, Joseph P; Wheeler, Paul A; Thorgaard, Gary H

    2014-09-01

    Variation in antipredator behavior may partially explain the survival differences seen between wild and hatchery trout and salmon. Antipredator behavior is thought to change during the domestication process, along with other traits. Investigations of antipredator behavior could benefit conservation efforts and supplementation programs. Our goal was to characterize the antipredator behavior in clonal rainbow trout lines derived from either wild or hatchery populations and identify genetic loci associated with variation between lines. We identified several behaviors that varied between clonal lines and QTL for several behavioral and size traits. Characterizing genetic variation underlying these behaviors may prove valuable in future conservation efforts by enabling monitoring of allele frequencies of loci affecting predation in wild populations.

  1. World-line perturbation theory

    CERN Document Server

    van Holten, Jan-Willem

    2016-01-01

    The motion of a compact body in space and time is commonly described by the world line of a point representing the instantaneous position of the body. In General Relativity such a world-line formalism is not quite straightforward because of the strict impossibility to accommodate point masses and rigid bodies. In many situations of practical interest it can still be made to work using an effective hamiltonian or energy-momentum tensor for a finite number of collective degrees of freedom of the compact object. Even so exact solutions of the equations of motion are often not available. In such cases families of world lines of compact bodies in curved space-times can be constructed by a perturbative procedure based on generalized geodesic deviation equations. Examples for simple test masses and for spinning test bodies are presented.

  2. Double Helix Nodal Line Superconductor

    Science.gov (United States)

    Sun, Xiao-Qi; Lian, Biao; Zhang, Shou-Cheng

    2017-10-01

    Time-reversal invariant superconductors in three dimensions may contain nodal lines in the Brillouin zone, which behave as Wilson loops of 3D momentum-space Chern-Simons theory of the Berry connection. Here we study the conditions of realizing linked nodal lines (Wilson loops), which yield a topological contribution to the thermal magnetoelectric coefficient that is given by the Chern-Simons action. We find the essential conditions are the existence of torus or higher genus Fermi surfaces and spiral spin textures. We construct such a model with two torus Fermi surfaces, where a generic spin-dependent interaction leads to double-helix-like linked nodal lines as the superconductivity is developed.

  3. Asymmetric Digital Subscriber Line (ADSL

    Directory of Open Access Journals (Sweden)

    Slavko Šarić

    2012-10-01

    Full Text Available ADSL (Asymmetric Digital Subscriber Line is a technologythat allows transmission at 8.488 Mbps over the existingtelephone copper line (speed range depending on the distance.ADSL circuit connects the ADSL modems by twisted-pairtelephone lines creating three infonnation channels: high speedsimplex (maximum 9 Mbps, medium speed duplex channel(maximum 2 Mbps and plain old telephone service channel.ADSL technology supports up to seven synchronous channelsthat can be configured to meet the needs of the end user.One could simultaneously view four movies stored in MPEG 1fonnat on separate television sets (MPEG 1 transmitted at 1.5Mbps, hold a video-conference (transmitted at 348 kbps,download data files from a server at 128 kbps via ISDN andeven receive a telephone call.

  4. Animated construction of line drawings

    KAUST Repository

    Fu, Hongbo

    2011-12-01

    Revealing the sketching sequence of a line drawing can be visually intriguing and used for video-based storytelling. Typically this is enabled based on tedious recording of artists\\' drawing process. We demonstrate that it is often possible to estimate a reasonable drawing order from a static line drawing with clearly defined shape geometry, which looks plausible to a human viewer. We map the key principles of drawing order from drawing cognition to computational procedures in our framework. Our system produces plausible animated constructions of input line drawings, with no or little user intervention. We test our algorithm on a range of input sketches, with varying degree of complexity and structure, and evaluate the results via a user study. We also present applications to gesture drawing synthesis and drawing animation creation especially in the context of video scribing.

  5. Animated construction of line drawings

    KAUST Repository

    Fu, Hongbo

    2011-12-01

    Revealing the sketching sequence of a line drawing can be visually intriguing and used for video-based storytelling. Typically this is enabled based on tedious recording of artists\\' drawing process. We demonstrate that it is often possible to estimate a reasonable drawing order from a static line drawing with clearly defined shape geometry, which looks plausible to a human viewer. We map the key principles of drawing order from drawing cognition to computational procedures in our framework. Our system produces plausible animated constructions of input line drawings, with no or little user intervention. We test our algorithm on a range of input sketches, with varying degree of complexity and structure, and evaluate the results via a user study. We also present applications to gesture drawing synthesis and drawing animation creation especially in the context of video scribing. © 2011 ACM.

  6. Double Helix Nodal Line Superconductor.

    Science.gov (United States)

    Sun, Xiao-Qi; Lian, Biao; Zhang, Shou-Cheng

    2017-10-06

    Time-reversal invariant superconductors in three dimensions may contain nodal lines in the Brillouin zone, which behave as Wilson loops of 3D momentum-space Chern-Simons theory of the Berry connection. Here we study the conditions of realizing linked nodal lines (Wilson loops), which yield a topological contribution to the thermal magnetoelectric coefficient that is given by the Chern-Simons action. We find the essential conditions are the existence of torus or higher genus Fermi surfaces and spiral spin textures. We construct such a model with two torus Fermi surfaces, where a generic spin-dependent interaction leads to double-helix-like linked nodal lines as the superconductivity is developed.

  7. Derivation of Ethnically Diverse Human Induced Pluripotent Stem Cell Lines.

    Science.gov (United States)

    Chang, Eun Ah; Tomov, Martin L; Suhr, Steven T; Luo, Jiesi; Olmsted, Zachary T; Paluh, Janet L; Cibelli, Jose

    2015-10-20

    The human genome with all its ethnic variations contributes to differences in human development, aging, disease, repair, and response to medical treatments and is an exciting area of research and clinical study. The availability of well-characterized ethnically diverse stem cell lines is limited and has not kept pace with other advances in stem cell research. Here we derived xenofree ethnically diverse-human induced pluripotent stem cell (ED-iPSC) lines from fibroblasts obtained from individuals of African American, Hispanic-Latino, Asian, and Caucasian ethnic origin and have characterized the lines under a uniform platform for comparative analysis. Derived ED-iPSC lines are low passage number and evaluated in vivo by teratoma formation and in vitro by high throughput microarray analysis of EB formation and early differentiation for tri-lineage commitment to endoderm, ectoderm and mesoderm. These new xenofree ED-iPSC lines represent a well-characterized valuable resource with potential for use in future research in drug discovery or clinical investigations.

  8. SYSTEMATIC AND STOCHASTIC VARIATIONS IN PULSAR DISPERSION MEASURES

    Energy Technology Data Exchange (ETDEWEB)

    Lam, M. T.; Cordes, J. M.; Chatterjee, S. [Department of Astronomy and Cornell Center for Astrophysics and Planetary Science, Cornell University, Ithaca, NY 14853 (United States); Jones, M. L.; McLaughlin, M. A. [Department of Physics and Astronomy, West Virginia University, Morgantown, WV 26506 (United States); Armstrong, J. W., E-mail: mlam@astro.cornell.edu [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States)

    2016-04-10

    We analyze deterministic and random temporal variations in the dispersion measure (DM) from the full three-dimensional velocities of pulsars with respect to the solar system, combined with electron-density variations over a wide range of length scales. Previous treatments have largely ignored pulsars’ changing distances while favoring interpretations involving changes in sky position from transverse motion. Linear trends in pulsar DMs observed over 5–10 year timescales may signify sizable DM gradients in the interstellar medium (ISM) sampled by the changing direction of the line of sight to the pulsar. We show that motions parallel to the line of sight can also account for linear trends, for the apparent excess of DM variance over that extrapolated from scintillation measurements, and for the apparent non-Kolmogorov scalings of DM structure functions inferred in some cases. Pulsar motions through atomic gas may produce bow-shock ionized gas that also contributes to DM variations. We discuss the possible causes of periodic or quasi-periodic changes in DM, including seasonal changes in the ionosphere, annual variations of the solar elongation angle, structure in the heliosphere and ISM boundary, and substructure in the ISM. We assess the solar cycle’s role on the amplitude of ionospheric and solar wind variations. Interstellar refraction can produce cyclic timing variations from the error in transforming arrival times to the solar system barycenter. We apply our methods to DM time series and DM gradient measurements in the literature and assess their consistency with a Kolmogorov medium. Finally, we discuss the implications of DM modeling in precision pulsar timing experiments.

  9. Assembly line performance and modeling

    Science.gov (United States)

    Rane, Arun B.; Sunnapwar, Vivek K.

    2017-03-01

    Automobile sector forms the backbone of manufacturing sector. Vehicle assembly line is important section in automobile plant where repetitive tasks are performed one after another at different workstations. In this thesis, a methodology is proposed to reduce cycle time and time loss due to important factors like equipment failure, shortage of inventory, absenteeism, set-up, material handling, rejection and fatigue to improve output within given cost constraints. Various relationships between these factors, corresponding cost and output are established by scientific approach. This methodology is validated in three different vehicle assembly plants. Proposed methodology may help practitioners to optimize the assembly line using lean techniques.

  10. Line locking and SS 433

    Science.gov (United States)

    Pekarevich, M.; Piran, T.; Shaham, J.

    1984-01-01

    The general problem of acceleration by line locking in an optically thin medium is considered. Analytic solutions to the coupled equations of radiation transfer and matter motion are presented. Using these solutions, restrictions on the physical conditions of the accelerated matter are derived. By applying these conditions to SS 433, it is found that if the absorbing ion is light (hydrogen or helium), the matter must be highly clumped, and the acceleration has to begin at approximately 10 to the 12th cm. Line-locking acceleration with a hydrogen-like heavy ion such as iron demands higher than solar ion abundance.

  11. Helium transfer line installation details.

    CERN Multimedia

    G. Perinic

    2007-01-01

    A particularity of the 32 m long four in one helium transfer line in between the cold box in USC55 and the cavern UX5 is the fact that the transfer line passes through a hole in the crane rail support beam. In order to ensure the alignment of the suspension rail in the interconnecting tunnel with the hole in the rail support as well as the connection points at both ends required precise measurements of the given geometries as well as the installation of a temporary target for the verification of the theoretical predictions.

  12. Nazca-Lines and Maria Reiche - I.

    Science.gov (United States)

    Kaifu, N.

    Huge and numerous geometrical lines and figures drawn on the stony desert near Nazca, Peru, are known as "Nazca Lines". Those lines might be the "largest calendar" which were drawn by ancient Peruvian towards the directions of setting and rising celestial bodies, proposes Maria Reiche, a great researcher and introducer of the Nazca Lines. The author reports the status of the Nazca Lines, and reviews the various studies to explain the purpose why the Nazca Lines were drawn.

  13. 46 CFR 45.31 - Deck line.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Deck line. 45.31 Section 45.31 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Load Line Marks § 45.31 Deck line. (a) Each vessel must be marked with a deck line on the outer surface of the shell on each side of...

  14. Maize inbreds exhibit high levels of copy number variation (CNV) and presence/absence variation (PAV) in genome content.

    Science.gov (United States)

    Springer, Nathan M; Ying, Kai; Fu, Yan; Ji, Tieming; Yeh, Cheng-Ting; Jia, Yi; Wu, Wei; Richmond, Todd; Kitzman, Jacob; Rosenbaum, Heidi; Iniguez, A Leonardo; Barbazuk, W Brad; Jeddeloh, Jeffrey A; Nettleton, Daniel; Schnable, Patrick S

    2009-11-01

    Following the domestication of maize over the past approximately 10,000 years, breeders have exploited the extensive genetic diversity of this species to mold its phenotype to meet human needs. The extent of structural variation, including copy number variation (CNV) and presence/absence variation (PAV), which are thought to contribute to the extraordinary phenotypic diversity and plasticity of this important crop, have not been elucidated. Whole-genome, array-based, comparative genomic hybridization (CGH) revealed a level of structural diversity between the inbred lines B73 and Mo17 that is unprecedented among higher eukaryotes. A detailed analysis of altered segments of DNA conservatively estimates that there are several hundred CNV sequences among the two genotypes, as well as several thousand PAV sequences that are present in B73 but not Mo17. Haplotype-specific PAVs contain hundreds of single-copy, expressed genes that may contribute to heterosis and to the extraordinary phenotypic diversity of this important crop.

  15. Fractional variational principles with delay

    Science.gov (United States)

    Baleanu, Dumitru; Maaraba Abdeljawad, Thabet; Jarad, Fahd

    2008-08-01

    The fractional variational principles within Riemann-Liouville fractional derivatives in the presence of delay are analyzed. The corresponding Euler-Lagrange equations are obtained and one example is analyzed in detail.

  16. Fractional variational principles with delay

    Energy Technology Data Exchange (ETDEWEB)

    Baleanu, Dumitru; Abdeljawad, Thabet Maaraba; Jarad, Fahd [Department of Mathematics and Computer Sciences, Faculty of Arts and Sciences, Cankaya University, 06530 Ankara (Turkey)], E-mail: dumitru@cankaya.edu.tr, E-mail: baleanu@venus.nipne.ro

    2008-08-08

    The fractional variational principles within Riemann-Liouville fractional derivatives in the presence of delay are analyzed. The corresponding Euler-Lagrange equations are obtained and one example is analyzed in detail.

  17. Genetic variation: a laboratory manual

    National Research Council Canada - National Science Library

    Weiner, Michael P; Gabriel, Stacey B; Stephens, J. Claiborne

    2007-01-01

    ... alterations, including copy number variation. The early sections of the manual are devoted to study design and generating genotype data, the use of resources such as HapMap and dbSNP, as well as experimental, statistical, and bioinformatic...

  18. Comparing variation across European countries

    DEFF Research Database (Denmark)

    Thygesen, Lau C; Baixauli-Pérez, Cristobal; Librero-López, Julián

    2015-01-01

    BACKGROUND: In geographical studies, population distribution is a key issue. An unequal distribution across units of analysis might entail extra-variation and produce misleading conclusions on healthcare performance variations. This article aims at assessing the impact of building more homogeneous...... units of analysis in the estimation of systematic variation in three countries. METHODS: Hospital discharges for six conditions (congestive heart failure, short-term complications of diabetes, hip fracture, knee replacement, prostatectomy in prostate cancer and percutaneous coronary intervention...... inhabitants vs. 7% in Denmark and 5% in England. Point estimates for Extremal Quotient and Interquartile Interval Ratio were lower in the three countries, particularly in less prevalent conditions. In turn, the Systematic Component of Variation and Empirical Bayes statistic were slightly lower in more...

  19. Sharecropping, interlinkage, and price variation

    OpenAIRE

    Debapriya Sen

    2005-01-01

    This paper proposes a theory of sharecropping and interlinkage on the basis of seasonal variation of price and imperfectly competitive nature of rural product markets. First, a benchmark model is considered to show the optimality of sharecropping in the presence of price variation. This model is extended by allowing interlinked contracts to show that there are multiple equilibria and both forms of contracts�fixed rental and sharecropping�can be sustained in equilibrium. Finally, incorpora...

  20. Classifying measures of biological variation.

    Directory of Open Access Journals (Sweden)

    Hans-Rolf Gregorius

    Full Text Available Biological variation is commonly measured at two basic levels: variation within individual communities, and the distribution of variation over communities or within a metacommunity. We develop a classification for the measurement of biological variation on both levels: Within communities into the categories of dispersion and diversity, and within metacommunities into the categories of compositional differentiation and partitioning of variation. There are essentially two approaches to characterizing the distribution of trait variation over communities in that individuals with the same trait state or type tend to occur in the same community (describes differentiation tendencies, and individuals with different types tend to occur in different communities (describes apportionment tendencies. Both approaches can be viewed from the dual perspectives of trait variation distributed over communities (CT perspective and community membership distributed over trait states (TC perspective. This classification covers most of the relevant descriptors (qualified measures of biological variation, as is demonstrated with the help of major families of descriptors. Moreover, the classification is shown to open ways to develop new descriptors that meet current needs. Yet the classification also reveals the misclassification of some prominent and widely applied descriptors: Dispersion is often misclassified as diversity, particularly in cases where dispersion descriptor allow for the computation of effective numbers; the descriptor GST of population genetics is commonly misclassified as compositional differentiation and confused with partitioning-oriented differentiation, whereas it actually measures partitioning-oriented apportionment; descriptors of β-diversity are ambiguous about the differentiation effects they are supposed to represent and therefore require conceptual reconsideration.

  1. A near infrared line list for \\NH: Analysis of a Kitt Peak spectrum after 35 years

    CERN Document Server

    Barton, Emma J; Tennyson, Jonathan; Béguier, S; Campargue, A

    2016-01-01

    A Fourier Transform (FT) absorption spectrum of room temperature NH3 in the region 7400 - 8600 cm-1 is analysed using a variational line list and ground state energies determined using the MARVEL procedure. The spectrum was measured by Dr Catherine de Bergh in 1980 and is available from the Kitt Peak data center. The centers and intensities of 8468 ammonia lines were retrieved using a multiline fitting procedure. 2474 lines are assigned to 21 bands providing 1692 experimental energies in the range 7000 - 9000 cm-1. The spectrum was assigned by the joint use of the BYTe variational line list and combination differences. The assignments and experimental energies presented in this work are the first for ammonia in the region 7400 - 8600 cm-1, considerably extending the range of known vibrational-excited states

  2. Variational integrators for electric circuits

    Energy Technology Data Exchange (ETDEWEB)

    Ober-Blöbaum, Sina, E-mail: sinaob@math.upb.de [Computational Dynamics and Optimal Control, University of Paderborn (Germany); Tao, Molei [Courant Institute of Mathematical Sciences, New York University (United States); Cheng, Mulin [Applied and Computational Mathematics, California Institute of Technology (United States); Owhadi, Houman; Marsden, Jerrold E. [Control and Dynamical Systems, California Institute of Technology (United States); Applied and Computational Mathematics, California Institute of Technology (United States)

    2013-06-01

    In this contribution, we develop a variational integrator for the simulation of (stochastic and multiscale) electric circuits. When considering the dynamics of an electric circuit, one is faced with three special situations: 1. The system involves external (control) forcing through external (controlled) voltage sources and resistors. 2. The system is constrained via the Kirchhoff current (KCL) and voltage laws (KVL). 3. The Lagrangian is degenerate. Based on a geometric setting, an appropriate variational formulation is presented to model the circuit from which the equations of motion are derived. A time-discrete variational formulation provides an iteration scheme for the simulation of the electric circuit. Dependent on the discretization, the intrinsic degeneracy of the system can be canceled for the discrete variational scheme. In this way, a variational integrator is constructed that gains several advantages compared to standard integration tools for circuits; in particular, a comparison to BDF methods (which are usually the method of choice for the simulation of electric circuits) shows that even for simple LCR circuits, a better energy behavior and frequency spectrum preservation can be observed using the developed variational integrator.

  3. Separating common from distinctive variation.

    Science.gov (United States)

    van der Kloet, Frans M; Sebastián-León, Patricia; Conesa, Ana; Smilde, Age K; Westerhuis, Johan A

    2016-06-06

    Joint and individual variation explained (JIVE), distinct and common simultaneous component analysis (DISCO) and O2-PLS, a two-block (X-Y) latent variable regression method with an integral OSC filter can all be used for the integrated analysis of multiple data sets and decompose them in three terms: a low(er)-rank approximation capturing common variation across data sets, low(er)-rank approximations for structured variation distinctive for each data set, and residual noise. In this paper these three methods are compared with respect to their mathematical properties and their respective ways of defining common and distinctive variation. The methods are all applied on simulated data and mRNA and miRNA data-sets from GlioBlastoma Multiform (GBM) brain tumors to examine their overlap and differences. When the common variation is abundant, all methods are able to find the correct solution. With real data however, complexities in the data are treated differently by the three methods. All three methods have their own approach to estimate common and distinctive variation with their specific strength and weaknesses. Due to their orthogonality properties and their used algorithms their view on the data is slightly different. By assuming orthogonality between common and distinctive, true natural or biological phenomena that may not be orthogonal at all might be misinterpreted.

  4. The Emission Line Luminosity Functions Of hα, OII, And OIII At 0PEARS

    Science.gov (United States)

    Pirzkal, Norbert; Malhotra, S.; Rhoads, J. E.; Ly, C.; Rothberg, B.; Straughn, A.; Meurer, G.

    2012-01-01

    Emission line galaxies are a powerful tracer of star formation in the Universe. By computing and examining the shape of the line luminosity function (the number density per logarithmic interval in line luminosity) we can study how star formation occurred in star forming galaxies. We can also look for variation in the line luminosity function of these objects as a function of redshift to look for evidence of evolution in the way star formation took place over the last few billion years. We present emission line luminosity functions obtained using the slitless grism survey data of the PEARS projects. We applied the PEARS-2D technique to pinpoint the location of line emission in field galaxies and hence were able to extract spectra of individual line emission regions in the PEARS fields, which covers a large fraction of the GOODS-N and GOODS-S fields. We detected lines with fluxes as low as 5. 10-18 erg/s/cm2 and identified Hα, OIII, OII, Hg and Lyα lines, over a redshift range of 0lines we identified are Hα (213 lines, 0lines, 0.2lines, 0.6line emission regions, multiple line emissions regions as well as several cases of multiple star forming regions in single galaxies. We present the luminosity functions for Hα, OII, and OIII computed across these relatively broad redshift ranges and conclude by examining the evolution of the Hα luminosity function from z=0.5 to z=0, the OII luminosity function from z=1.7 to z=0.6, and the OIII luminosity function from z=1.0 to z=0.2.

  5. Drawing Lines and Taking Sides

    DEFF Research Database (Denmark)

    Leitheiser, Erin

    Companies increasingly engage in CSR via international private governance arrangements, yet little is known about why companies make the choices that they do. By building upon the concept of national business system variations in CSR practices, this study uses the concept of organizing to propose...

  6. Streaming Algorithms for Line Simplification

    DEFF Research Database (Denmark)

    Abam, Mohammad; de Berg, Mark; Hachenberger, Peter

    2010-01-01

    We study the following variant of the well-known line-simplification problem: we are getting a (possibly infinite) sequence of points p 0,p 1,p 2,… in the plane defining a polygonal path, and as we receive the points, we wish to maintain a simplification of the path seen so far. We study this pro...

  7. CERN Video News on line

    CERN Multimedia

    2003-01-01

    The latest CERN video news is on line. In this issue : an interview with the Director General and reports on the new home for the DELPHI barrel and the CERN firemen's spectacular training programme. There's also a vintage video news clip from 1954. See: www.cern.ch/video or Bulletin web page

  8. Persistent diffusion on a line

    Science.gov (United States)

    Balakrishnan, V.; Chaturvedi, S.

    1988-02-01

    We consider solutions to the telegraph equation describing persistent diffusion on a line under various initial conditions. The first passage time distribution is evaluated in closed form. Biased persistent diffusion is also considered. A direct derivation of the telegraph equation from the stochastic equation for the displacement is presented in an appendix.

  9. Software product lines : Organizational alternatives

    NARCIS (Netherlands)

    Bosch, J

    2001-01-01

    Software product lines enjoy increasingly wide adoption in the software industry. Most authors focus on the technical and process aspects and assume an organizational model consisting of a domain engineering unit and several application engineering units. In our cooperation with several software

  10. Reconnections of Wave Vortex Lines

    Science.gov (United States)

    Berry, M. V.; Dennis, M. R.

    2012-01-01

    When wave vortices, that is nodal lines of a complex scalar wavefunction in space, approach transversely, their typical crossing and reconnection is a two-stage process incorporating two well-understood elementary events in which locally coplanar hyperbolas switch branches. The explicit description of this reconnection is a pedagogically useful…

  11. Managing first-line failure

    Directory of Open Access Journals (Sweden)

    David A Cooper

    2014-11-01

    Full Text Available WHO standard of care for failure of a first regimen, usually 2N(tRTI's and an NNRTI, consists of a ritonavir-boosted protease inhibitor with a change in N(tRTI's. Until recently, there was no evidence to support these recommendations which were based on expert opinion. Two large randomized clinical trials, SECOND LINE and EARNEST both showed excellent response rates (>80% for the WHO standard of care and indicated that a novel regimen of a boosted protease inhibitor with an integrase inhibitor had equal efficacy with no difference in toxicity. In EARNEST, a third arm consisting of induction with the combined protease and integrase inhibitor followed by protease inhibitor monotherapy maintenance was inferior and led to substantial (20% protease inhibitor resistance. These studies confirm the validity of the current recommendations of WHO and point to a novel public health approach of using two new classes for second line when standard first-line therapy has failed, which avoids resistance genotyping. Notwithstanding, adherence must be stressed in those failing first-line treatments. Protease inhibitor monotherapy is not suitable for a public health approach in low- and middle-income countries.

  12. Coiled transmission line pulse generators

    Science.gov (United States)

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  13. Line bundles and flat connections

    Indian Academy of Sciences (India)

    /fulltext/pmsc/127/03/0547-0549. Keywords. Calabi–Yau threefold; torsion; cocompact lattice; unitary representation. Abstract. We prove that there are cocompact lattices Γ in S L ( 2 , C ) with the property that there are holomorphic line bundles ...

  14. Managing first-line failure.

    Science.gov (United States)

    Cooper, David A

    2014-01-01

    WHO standard of care for failure of a first regimen, usually 2N(t)RTI's and an NNRTI, consists of a ritonavir-boosted protease inhibitor with a change in N(t)RTI's. Until recently, there was no evidence to support these recommendations which were based on expert opinion. Two large randomized clinical trials, SECOND LINE and EARNEST both showed excellent response rates (>80%) for the WHO standard of care and indicated that a novel regimen of a boosted protease inhibitor with an integrase inhibitor had equal efficacy with no difference in toxicity. In EARNEST, a third arm consisting of induction with the combined protease and integrase inhibitor followed by protease inhibitor monotherapy maintenance was inferior and led to substantial (20%) protease inhibitor resistance. These studies confirm the validity of the current recommendations of WHO and point to a novel public health approach of using two new classes for second line when standard first-line therapy has failed, which avoids resistance genotyping. Notwithstanding, adherence must be stressed in those failing first-line treatments. Protease inhibitor monotherapy is not suitable for a public health approach in low- and middle-income countries.

  15. Correction of a bootstrap approach to testing for evolution along lines of least resistance.

    Science.gov (United States)

    Berner, D

    2009-12-01

    Testing for an association between the leading vectors of multivariate trait (co)variation within populations (the 'line of least resistance') and among populations is an important tool for exploring variational bias in evolution. In a recent study of stickleback fish populations, a bootstrap-based test was introduced that takes into account estimation error in both vectors and hence improves the previously available bootstrap method. Because this test was implemented incorrectly, however, I here describe the correct test protocol and provide a reanalysis of the original data set. The application of this new test protocol should improve future investigations of evolution along lines of least resistance and other vector comparisons.

  16. On the origin of cyclotron lines in the spectra of X-ray pulsars

    Directory of Open Access Journals (Sweden)

    Mushtukov A. A.

    2014-01-01

    Full Text Available Cyclotron resonance scattering features are observed in the spectra of some X-ray pulsars and show significant changes in the line energy with the pulsar luminosity. In a case of bright sources, the line centroid energy is anti-correlated with the luminosity. Such a behaviour is often associated with the onset and growth of the accretion column, which is believed to be the origin of the observed emission and the cyclotron lines. However, this scenario inevitably implies large gradient of the magnetic field strength within the line-forming region, and it makes the formation of the observed line-like features problematic. Moreover, the observed variation of the cyclotron line energy is much smaller than could be anticipated for the corresponding luminosity changes. We argue that a more physically realistic situation is that the cyclotron line forms when the radiation emitted by the accretion column is reflected from the neutron star surface. The idea is based on the facts that a substantial part of column luminosity is intercepted by the neutron star surface and the reflected radiation should contain absorption features. The reflection model is developed and applied to explain the observed variations of the cyclotron line energy in a bright X-ray pulsar V 0332+53 over a wide range of luminosities.

  17. On-line monitoring of methane in sewer air.

    Science.gov (United States)

    Liu, Yiwen; Sharma, Keshab R; Murthy, Sudhir; Johnson, Ian; Evans, Ted; Yuan, Zhiguo

    2014-10-16

    Methane is a highly potent greenhouse gas and contributes significantly to climate change. Recent studies have shown significant methane production in sewers. The studies conducted so far have relied on manual sampling followed by off-line laboratory-based chromatography analysis. These methods are labor-intensive when measuring methane emissions from a large number of sewers, and do not capture the dynamic variations in methane production. In this study, we investigated the suitability of infrared spectroscopy-based on-line methane sensors for measuring methane in humid and condensing sewer air. Two such sensors were comprehensively tested in the laboratory. Both sensors displayed high linearity (R(2) > 0.999), with a detection limit of 0.023% and 0.110% by volume, respectively. Both sensors were robust against ambient temperature variations in the range of 5 to 35°C. While one sensor was robust against humidity variations, the other was found to be significantly affected by humidity. However, the problem was solved by equipping the sensor with a heating unit to increase the sensor surface temperature to 35°C. Field studies at three sites confirmed the performance and accuracy of the sensors when applied to actual sewer conditions, and revealed substantial and highly dynamic methane concentrations in sewer air.

  18. Relating quantitative variation within a behavior to variation in transcription.

    Science.gov (United States)

    Benowitz, Kyle M; McKinney, Elizabeth C; Cunningham, Christopher B; Moore, Allen J

    2017-08-01

    Many studies have shown that variation in transcription is associated with changes in behavioral state, or with variation within a state, but little has been done to address if the same genes are involved in both. Here, we investigate the transcriptional basis of variation in parental provisioning using two species of burying beetle, Nicrophorus orbicollis and Nicrophorus vespilloides. We used RNA-seq to compare transcription in parents that provided high amounts of provisioning behavior versus low amounts in males and females of each species. We found no overarching transcriptional patterns distinguishing high from low caring parents, and no informative transcripts that displayed particularly large expression differences in either sex. However, we did find subtler gene expression differences between high and low provisioning parents that are consistent across both sexes and species. Furthermore, we show that transcripts previously implicated in transitioning into parental care in N. vespilloides had high variance in the levels of transcription and were unusually likely to display differential expression between high and low provisioning parents. Thus, quantitative behavioral variation appears to reflect many transcriptional differences of small effect. Furthermore, the same transcripts required for the transition between behavioral states are also related to variation within a behavioral state. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  19. Molecular and functional characterization of cry1Ac transgenic pea lines

    OpenAIRE

    Teressa Negawo, Alemayehu; Baranek, Linda; Jacobsen, Hans-Jörg; Hassan, Fathi

    2016-01-01

    Transgenic pea lines transformed with the cry1Ac gene were characterized at molecular (PCR, RT-PCR, qRT-PCR and immunostrip assay) and functional levels (leaf paint and insect feeding bioassays). The results showed the presence, expression, inheritance and functionality of the introduced transgene at different progeny levels. Variation in the expression of the cry1Ac gene was observed among the different transgenic lines. In the insect bioassay studies using the larvae of Heliothis virescens,...

  20. Elucidating genetic variation in Candidatus Liberibacter asiaticus transmission between Asian citrus psyllid isofemale lines

    OpenAIRE

    Dixon, Danielle; Kruse, Annie; Ramsey, John; Hosmani, Prashant; Hall, David; Saha, Surya; Ammar, El-Desouky; Cilia, Michelle; Mueller, Lukas A.

    2017-01-01

    Citrus greening disease or Huanglongbing (HLB) is an epidemic bacterial infection that has devastated citrus industries across the globe. HLB leads to a reduction in fruit quality, decrease in overall fruit production and eventual death of the citrus tree.The disease is associated with this bacterium Candidatus Liberibacter asiaticus (CLas), is transmitted by the Asian citrus psyllid (ACP).Objective 1: Improve the current psyllid genome through manual curation.Objective 2: Characterize genet...

  1. Variational formulation of the method of lines and its application to the wave propagation problems

    CSIR Research Space (South Africa)

    Shatalov, M

    2011-07-01

    Full Text Available accuracy is ( )3 ,O h u t x???? ??? ? (for (1) the error has order ( )2 ,O h u t x??? ??? ? ). For the second order derivative: 18th International Congress on Sound and Vibration, Rio de Janeiro, Brazil, 10-14 July 2011 3... ? ??? ?? ??? ? and first derivative calculation with accuracy ( ) 2 2 2 ,u t xO h x ? ?? ?? ??? ? , gives us the same result as application of the finite difference scheme of accuracy ( ) 4 4 4 ,u t xO h x ? ?? ?? ??? ? to calculation of the second...

  2. Short-Term Hα Line Variations in Classical Be Stars: 59 Cyg and OT ...

    Indian Academy of Sciences (India)

    2009-07-23

    Jul 23, 2009 ... Abstract. We present the optical spectroscopic study of two classical Be stars, 59 Cyg and OT Gem obtained over a period of few months in 2009. We detected a rare triple-peak Hα emission phase in. 59 Cyg and a rapid decrease in the emission strength of Hα in OT Gem, which are used to understand.

  3. Variations in Humanized and Defined Culture Conditions Supporting Derivation of New Human Embryonic Stem Cell Lines

    DEFF Research Database (Denmark)

    Fletcher, Judy M; Ferrier, Patricia M; Gardner, John O

    2006-01-01

    The evolution of "humanized" (i.e., free of animal sourced reagents) and ultimately chemically defined culture systems for human embryo stem cell (hESC) isolation and culture is of importance to improving their efficacy and safety in research and therapeutic applications. This can be achieved...... serum-free medium (SFM) containing only human sourced and recombinant protein. Further, outgrowth of embryonic cells from whole blastocysts in both media could be achieved for up to 1 week without reliance on feeder cells. All variant conditions sustained undifferentiated cell status, a stable karyotype......, with a transitional requirement for human feeder cells. This represents another sequential step in the generation of therapeutic grade stem cells with reduced risk of zoonotic pathogen transmission....

  4. Analysis of Power Network for Line Reactance Variation to Improve Total Transmission Capacity

    NARCIS (Netherlands)

    Ullah, Ikram; Gawlik, Wolfgang; Palensky, P.

    2016-01-01

    The increasing growth in power demand and the penetration of renewable distributed generations in competitive electricity market demands large and flexible capacity from the transmission grid to reduce transmission bottlenecks. The bottlenecks cause transmission congestion, reliability problems,

  5. Is there much variation in variation? Revisiting statistics of small area variation in health services research

    Directory of Open Access Journals (Sweden)

    Ibáñez Berta

    2009-04-01

    Full Text Available Abstract Background The importance of Small Area Variation Analysis for policy-making contrasts with the scarcity of work on the validity of the statistics used in these studies. Our study aims at 1 determining whether variation in utilization rates between health areas is higher than would be expected by chance, 2 estimating the statistical power of the variation statistics; and 3 evaluating the ability of different statistics to compare the variability among different procedures regardless of their rates. Methods Parametric bootstrap techniques were used to derive the empirical distribution for each statistic under the hypothesis of homogeneity across areas. Non-parametric procedures were used to analyze the empirical distribution for the observed statistics and compare the results in six situations (low/medium/high utilization rates and low/high variability. A small scale simulation study was conducted to assess the capacity of each statistic to discriminate between different scenarios with different degrees of variation. Results Bootstrap techniques proved to be good at quantifying the difference between the null hypothesis and the variation observed in each situation, and to construct reliable tests and confidence intervals for each of the variation statistics analyzed. Although the good performance of Systematic Component of Variation (SCV, Empirical Bayes (EB statistic shows better behaviour under the null hypothesis, it is able to detect variability if present, it is not influenced by the procedure rate and it is best able to discriminate between different degrees of heterogeneity. Conclusion The EB statistics seems to be a good alternative to more conventional statistics used in small-area variation analysis in health service research because of its robustness.

  6. US line-ups outperform UK line-ups

    OpenAIRE

    Seale-Carlisle, Travis M.; Mickes, Laura

    2016-01-01

    In the USA and the UK, many thousands of police suspects are identified by eyewitnesses every year. Unfortunately, many of those suspects are innocent, which becomes evident when they are exonerated by DNA testing, often after having been imprisoned for years. It is, therefore, imperative to use identification procedures that best enable eyewitnesses to discriminate innocent from guilty suspects. Although police investigators in both countries often administer line-up procedures, the details ...

  7. Spectral Line Shapes of He I Line 3889 Å

    Directory of Open Access Journals (Sweden)

    Banaz Omar

    2014-06-01

    Full Text Available Spectral line shapes of neutral helium 3889 Å(23S–33P transition line are calculated by using several theoretical methods. The electronic contribution to the line broadening is calculated from quantum statistical many-particle theory by using thermodynamic Green's function, including dynamic screening of the electron-atom interaction. The ionic contribution is taken into account in a quasistatic approximation, where a static microfield distribution function is presented. Strong electron collisions are consistently considered with an effective two-particle T-matrix approach, where Convergent Close Coupling method gives scattering amplitudes including Debye screening for neutral helium. Then the static profiles converted to dynamic profiles by using the Frequency Fluctuation Model. Furthermore, Molecular Dynamics simulations for interacting and independent particles are used where the dynamic sequence of microfield is taken into account. Plasma parameters are diagnosed and good agreements are shown by comparing our theoretical results with the recent experimental result of Jovićević et al. (J. Phys. B: At. Mol. Opt. Phys. 2005, 38, 1249. Additionally, comparison with various experimental data in a wide range of electron density ne ≈ (1022− 1024m−3 and temperature T ≈ (2−6 × 104 K are presented.

  8. Genetic and epigenetic changes in somatic hybrid introgression lines between wheat and tall wheatgrass.

    Science.gov (United States)

    Liu, Shuwei; Li, Fei; Kong, Lina; Sun, Yang; Qin, Lumin; Chen, Suiyun; Cui, Haifeng; Huang, Yinghua; Xia, Guangmin

    2015-04-01

    Broad phenotypic variations were induced in derivatives of an asymmetric somatic hybridization of bread wheat (Triticum aestivum) and tall wheatgrass (Thinopyrum ponticum Podp); however, how these variations occurred was unknown. We explored the nature of these variations by cytogenetic assays and DNA profiling techniques to characterize six genetically stable somatic introgression lines. Karyotyping results show the six lines similar to their wheat parent, but GISH analysis identified the presence of a number of short introgressed tall wheatgrass chromatin segments. DNA profiling revealed many genetic and epigenetic differences, including sequences deletions, altered regulation of gene expression, changed patterns of cytosine methylation, and the reactivation of retrotransposons. Phenotypic variations appear to result from altered repetitive sequences combined with the epigenetic regulation of gene expression and/or retrotransposon transposition. The extent of genetic and epigenetic variation due to the maintenance of parent wheat cells in tissue culture was assessed and shown to be considerably lower than had been induced in the introgression lines. Asymmetric somatic hybridization provides appropriate material to explore the nature of the genetic and epigenetic variations induced by genomic shock. Copyright © 2015 by the Genetics Society of America.

  9. Can Social Cognitive Theory Constructs Explain Socio-Economic Variations in Adolescent Eating Behaviours? A Mediation Analysis

    Science.gov (United States)

    Ball, K.; MacFarlane, A.; Crawford, D.; Savige, G.; Andrianopoulos, N.; Worsley, A.

    2009-01-01

    Adolescents of low socio-economic position (SEP) are less likely than those of higher SEP to consume diets in line with current dietary recommendations. The reasons for these SEP variations remain poorly understood. We investigated the mechanisms underlying socio-economic variations in adolescents' eating behaviours using a theoretically derived…

  10. LINE-1 Retrotransposition Activity in Human Genomes

    Science.gov (United States)

    Beck, Christine R.; Collier, Pamela; Macfarlane, Catriona; Malig, Maika; Kidd, Jeffrey M.; Eichler, Evan E.; Badge, Richard M.; Moran, John V.

    2010-01-01

    Summary Long Interspersed Element-1 (LINE-1 or L1) sequences comprise the bulk of retrotransposition activity in the human genome; however, the abundance of highly active or ‘hot’ L1s in the human population remains largely unexplored. Here, we used a fosmid-based, paired-end DNA sequencing strategy to identify 68 full-length L1s which are differentially present among individuals but are absent from the human genome reference sequence. The majority of these L1s were highly active in a cultured cell retrotransposition assay. Genotyping 26 elements revealed that two L1s are only found in Africa and that two more are absent from the H952 subset of the Human Genome Diversity Panel. Therefore, these results suggest that ‘hot’ L1s are more abundant in the human population than previously appreciated, and that ongoing L1 retrotransposition continues to be a major source of inter-individual genetic variation. PMID:20602998

  11. Transmission line studies for ITER compatible reflectometers

    NARCIS (Netherlands)

    Wagner, D.; Kasparek, W.; Gantenbein, G.; Manso, M. E.; Sanchez, J.; Donne, A. J. H.

    1997-01-01

    Corrugated circular transmission lines are considered as high performance, low loss, broadband lines for reflectometry on ITER. These lines are proposed as a possible solution for the equatorial low-field-side system and as a part (receiver-vacuum vessel) of the transmission lines for the high-field

  12. 18 CFR 2.2 - Transmission lines.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Transmission lines. 2.2... Under the Federal Power Act § 2.2 Transmission lines. In a public statement dated March 7, 1941, the Commission announced its determination that transmission lines which are not primary lines transmitting power...

  13. Understanding human DNA sequence variation.

    Science.gov (United States)

    Kidd, K K; Pakstis, A J; Speed, W C; Kidd, J R

    2004-01-01

    Over the past century researchers have identified normal genetic variation and studied that variation in diverse human populations to determine the amounts and distributions of that variation. That information is being used to develop an understanding of the demographic histories of the different populations and the species as a whole, among other studies. With the advent of DNA-based markers in the last quarter century, these studies have accelerated. One of the challenges for the next century is to understand that variation. One component of that understanding will be population genetics. We present here examples of many of the ways these new data can be analyzed from a population perspective using results from our laboratory on multiple individual DNA-based polymorphisms, many clustered in haplotypes, studied in multiple populations representing all major geographic regions of the world. These data support an "out of Africa" hypothesis for human dispersal around the world and begin to refine the understanding of population structures and genetic relationships. We are also developing baseline information against which we can compare findings at different loci to aid in the identification of loci subject, now and in the past, to selection (directional or balancing). We do not yet have a comprehensive understanding of the extensive variation in the human genome, but some of that understanding is coming from population genetics.

  14. Seasonal variation in sports participation.

    Science.gov (United States)

    Schüttoff, Ute; Pawlowski, Tim

    2018-02-01

    This study explores indicators describing socio-demographics, sports participation characteristics and motives which are associated with variation in sports participation across seasons. Data were drawn from the German Socio-Economic Panel which contains detailed information on the sports behaviour of adults in Germany. Overall, two different measures of seasonal variation are developed and used as dependent variables in our regression models. The first variable measures the coefficient of (seasonal) variation in sport-related energy expenditure per week. The second variable measures whether activity drops below the threshold as defined by the World Health Organization (WHO). Results suggest that the organisational setting, the intensity and number of sports practised, and the motive for participation are strongly correlated with the variation measures used. For example, both, participation in a sports club and a commercial facility, are associated with reduced seasonal variation and a significantly higher probability of participating at a volume above the WHO threshold across all seasons. These findings give some impetus for policymaking and the planning of sports programmes as well as future research directions.

  15. The Role of Variation in Lexicography.

    Science.gov (United States)

    Lucas, Ceil

    2003-01-01

    Explores the relationship between lexicography and variation in both spoken languages and sign languages. Examines the function of dictionaries and discusses the nature of linguistic variation, using an example of lexical variation in American Sign Language. (Author/VWL)

  16. Effects of drain bias on the statistical variation of double-gate tunnel field-effect transistors

    Science.gov (United States)

    Choi, Woo Young

    2017-04-01

    The effects of drain bias on the statistical variation of double-gate (DG) tunnel field-effect transistors (TFETs) are discussed in comparison with DG metal-oxide-semiconductor FETs (MOSFETs). Statistical variation corresponds to the variation of threshold voltage (V th), subthreshold swing (SS), and drain-induced barrier thinning (DIBT). The unique statistical variation characteristics of DG TFETs and DG MOSFETs with the variation of drain bias are analyzed by using full three-dimensional technology computer-aided design (TCAD) simulation in terms of the three dominant variation sources: line-edge roughness (LER), random dopant fluctuation (RDF) and workfunction variation (WFV). It is observed than DG TFETs suffer from less severe statistical variation as drain voltage increases unlike DG MOSFETs.

  17. Nazca-lines and Maria Reiche - II.

    Science.gov (United States)

    Kaifu, N.

    Huge and numerous geometrical lines and figures drawn on the stony desert near Nazca, Peru, are known as "Nazca Lines". Those lines might be the "largest calendar" which were drawn towards the directions of setting and rising celestial bodies by ancient Peruvian, proposes Maria Reiche, a great researcher and introducer of the Nazca Lines. The future of the Nazca Lines is seriously concerned due to the recent rapid developments in Peru. The author reports the status of the Nazca Lines, and reviews the various studies to explain the purpose why the Nazca Lines were drawn.

  18. LINE-1 Cultured Cell Retrotransposition Assay

    Science.gov (United States)

    Kopera, Huira C.; Larson, Peter A.; Moldovan, John B.; Richardson, Sandra R.; Liu, Ying; Moran, John V.

    2016-01-01

    Summary The Long INterspersed Element-1 (LINE-1 or L1) retrotransposition assay has facilitated the discovery and characterization of active (i.e., retrotransposition-competent) LINE-1 sequences from mammalian genomes. In this assay, an engineered LINE-1 containing a retrotransposition reporter cassette is transiently transfected into a cultured cell line. Expression of the reporter cassette, which occurs only after a successful round of retrotransposition, allows the detection and quantification of the LINE-1 retrotransposition efficiency. This assay has yielded insight into the mechanism of LINE-1 retrotransposition. It also has provided a greater understanding of how the cell regulates LINE-1 retrotransposition and how LINE-1 retrotransposition impacts the structure of mammalian genomes. Below, we provide a brief introduction to LINE-1 biology and then detail how the LINE-1 retrotransposition assay is performed in cultured mammalian cells. PMID:26895052

  19. Forecasting for dynamic line rating

    DEFF Research Database (Denmark)

    Michiorri, Andrea; Nguyen, Huu-Minh; Alessandrini, Stefano

    2015-01-01

    This paper presents an overview of the state of the art on the research on Dynamic Line Rating forecasting. It is directed at researchers and decision-makers in the renewable energy and smart grids domain, and in particular at members of both the power system and meteorological community. Its aim...... sensors on the line that measure conductor temperature, tension, sag or environmental parameters such as wind speed and air temperature. Because of the conservative assumptions used to calculate static seasonal ampacity limits and the variability of weather parameters, DLRs are considerably higher than....... In order to facilitate the integration of DLR into power system operations, research has been launched into DLR forecasting, following a similar avenue to IRS production forecasting, i.e. based on a mix of statistical methods and meteorological forecasts. The development of reliable DLR forecasts...

  20. Line Creep in Paper Peeling

    Directory of Open Access Journals (Sweden)

    Rosti J.

    2010-06-01

    Full Text Available We have studied experimentally the dynamics of the separation of a sheet of paper into two halves in a peeling configuration. The experimental setup consists of a peeling device, where a fracture front is driven along the plane of the paper, with a constant force. The theoretical picture is how an elastic line interacts with a random landscape of fracture toughness. We compare the results with theoretical simulations in several aspects. One recent finding concerns the autocorrelation function of the average front position. The data from the experiments produces so-called cusps or singularities in the correlation function, as predicted by the functional renormalization group theory for elastic lines. Comparisons with simulations with either a short range or a long range elastic kernel demonstrate that the latter agrees with the experimental observations, as expected.

  1. On-line moisture analysis

    CERN Document Server

    Cutmore, N G

    2002-01-01

    Measurement of the moisture content of iron ore has become a key issue for controlling moisture additions for dust suppression. In most cases moisture content is still determined by manual or automatic sampling of the ore stream, followed by conventional laboratory analysis by oven drying. Although this procedure enables the moisture content to be routinely monitored, it is too slow for control purposes. This has generated renewed interest in on-line techniques for the accurate and rapid measurement of moisture in iron ore on conveyors. Microwave transmission techniques have emerged over the past 40 years as the dominant technology for on-line measurement of moisture in bulk materials, including iron ores. Alternative technologies have their limitations. Infra-red analysers are used in a variety of process industries, but rely on the measurement of absorption by moisture in a very thin surface layer. Consequently such probes may be compromised by particle size effects and biased presentation of the bulk mater...

  2. Transversal Lines of the Debates

    Directory of Open Access Journals (Sweden)

    Yolanda Onghena

    1998-12-01

    Full Text Available The Transversal Lines of the Debates gathers for publication the presentations of the scholars invited to the seminar. In the papers, Yolanda Onghena observes that the evolution from the cultural to the inter-cultural travels along four axes: the relations between cultureand society; the processes of change within identity-based dynamics; the representations of the Other; and, interculturality. Throughout the presentations and subsequent debates, whenever the different participants referred to aspects of the cultural identity problematic--”angst”, “obsession”, “deficit”, manipulation”, and others, these same participants in the Transversal Lines of the Debates also showed that, in certain areas, an optimistic viewpoint is not out of the question.

  3. Line graphs as social networks

    Science.gov (United States)

    Krawczyk, M. J.; Muchnik, L.; Mańka-Krasoń, A.; Kułakowski, K.

    2011-07-01

    It was demonstrated recently that the line graphs are clustered and assortative. These topological features are known to characterize some social networks [M.E.J. Newman, Y. Park, Why social networks are different from other types of networks, Phys. Rev. E 68 (2003) 036122]; it was argued that this similarity reveals their cliquey character. In the model proposed here, a social network is the line graph of an initial network of families, communities, interest groups, school classes and small companies. These groups play the role of nodes, and individuals are represented by links between these nodes. The picture is supported by the data on the LiveJournal network of about 8×10 6 people.

  4. About cosmic gamma ray lines

    Science.gov (United States)

    Diehl, Roland

    2017-06-01

    Gamma ray lines from cosmic sources convey the action of nuclear reactions in cosmic sites and their impacts on astrophysical objects. Gamma rays at characteristic energies result from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. The gamma-ray line from the annihilation of positrons at 511 keV falls into the same energy window, although of different origin. We present here the concepts of cosmic gamma ray spectrometry and the corresponding instruments and missions, followed by a discussion of recent results and the challenges and open issues for the future. Among the lessons learned are the diffuse radioactive afterglow of massive-star nucleosynthesis in 26Al and 60Fe gamma rays, which is now being exploited towards the cycle of matter driven by massive stars and their supernovae; large interstellar cavities and superbubbles have been recognised to be of key importance here. Also, constraints on the complex processes making stars explode as either thermonuclear or core-collapse supernovae are being illuminated by gamma-ray lines, in this case from shortlived radioactivities from 56Ni and 44Ti decays. In particular, the three-dimensionality and asphericities that have recently been recognised as important are enlightened in different ways through such gamma-ray line spectroscopy. Finally, the distribution of positron annihilation gamma ray emission with its puzzling bulge-dominated intensity disctribution is measured through spatially-resolved spectra, which indicate that annihilation conditions may differ in different parts of our Galaxy. But it is now understood that a variety of sources may feed positrons into the interstellar medium, and their characteristics largely get lost during slowing down and propagation of positrons before annihilation; a recent microquasar flare was caught as an opportunity to see positrons annihilate at a source.

  5. Assembly delay line pulse generators

    CERN Multimedia

    CERN PhotoLab

    1971-01-01

    Assembly of six of the ten delay line pulse generators that will power the ten kicker magnet modules. One modulator part contains two pulse generators. Capacitors, inductances, and voltage dividers are in the oil tank on the left. Triggered high-pressure spark gap switches are on the platforms on the right. High voltage pulse cables to the kicker magnet emerge under the spark gaps. In the centre background are the assembled master gaps.

  6. Chalk Line Mill, Anniston, AL

    Science.gov (United States)

    The Chalk Line Mill property was the site of a textile mill which operated from 1887 until 1994. Demolition activities in 2004 removed most of the structures on-site, but also left large, unsightly piles of debris scattered across this 14-acre property. The City applied for and received a $200,000 Brownfields cleanup grant in 2007 to address contamination on the property and the Appalachian Regional Commission provided an additional $150,000 in funding.

  7. ac transmission line field measurements

    Energy Technology Data Exchange (ETDEWEB)

    Kotter, F.R.; Misakian, M.

    1977-11-01

    The concern in recent years over the environmental effects of electric and magnetic fields from high voltage transmission lines has also focused attention on the accuracy of measurements of these fields. Electric field meters are discussed in terms of theory of operation, parameters affecting performance, meter performance under field and laboratory conditions, and calibration procedures. The performance and calibration of magnetic field meters is described. (LCL)

  8. Firing up the front line.

    Science.gov (United States)

    Katzenbach, J R; Santamaria, J A

    1999-01-01

    For many organizations, achieving competitive advantage means eliciting superior performance from employees on the front line--the burger flippers, hotel room cleaners, and baggage handlers whose work has an enormous effect on customers. That's no easy task. Front line workers are paid low wages, have scant hope of advancement, and--not surprisingly--often care little about the company's performance. But then how do some companies succeed in engaging the emotional energy of rank-and-file workers? A team of researchers at McKinsey & Company and the Conference Board recently explored that question and discovered that one highly effective route is demonstrated by the U.S. Marine Corps. The Marines' approach to motivation follows the "mission, values, and pride" path, which researchers say is practical and relevant for the business world. More specifically, the authors say the Marines follow five practices: they over-invest in cultivating core value; prepare every person to lead, including front line supervisors; learn when to create teams and when to create single-leader work groups; attend to all employees, not just the top half; and encourage self-discipline as a way of building pride. The authors admit there are critical differences between the Marines and most businesses. But using vivid examples from companies such as KFC and Marriott International, the authors illustrate how the Marines' approach can be translated for corporate use. Sometimes, the authors maintain, minor changes in a company's standard operating procedure can have a powerful effect on front line pride and can result in substantial payoffs in company performance.

  9. On-line survey method

    OpenAIRE

    Dvornáková, Táňa

    2008-01-01

    Thesis deals with modern ways of surveys using advancing information technology and internet which makes surveys using web applications more effective. After a short review of public opinion history the summary of principal czech and forign survey organizations engaged in determination of survey rules are presented. Thesis follows with description of classic and modern data collecting methods. Main attention is devoted to on-line survey method. The description of method, possibilities of real...

  10. Diccionario de neologismos on line

    OpenAIRE

    Institut Universitari de Lingstica Aplicada; Institut Universitari de Lingüística Aplicada

    2010-01-01

    El Diccionario de neologismos on line es una obra lexicográfica que recoge más de 4.000 neologismos en castellano documentados entre 1989 y 2007, mayoritariamente en prensa escrita. Los neologismos van acompañados de definición lexicográfica y varios contextos de uso, además de informaciones sobre la categoría grammatical, la fuente y fecha de procedencia, etc.

  11. Replication timing kept in LINE.

    Science.gov (United States)

    O'Neill, Rachel J; O'Neill, Michael J

    2018-01-18

    Accurate and synchronous replication timing between chromosome homologues is essential for maintaining chromosome stability, yet how this is achieved has remained a mystery. In this issue, Platt et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201707082) identify antisense LINE (L1) transcripts within long noncoding RNAs as the critical factor in maintaining synchronous chromosome-wide replication timing. © 2018 O'Neill and O'Neill.

  12. Line-Editor Computer Program

    Science.gov (United States)

    Scott, Peter J.

    1989-01-01

    ZED editing program for DEC VAX computer simple, powerful line editor for text, program source code, and nonbinary data. Excels in processing of text by use of procedure files. Also features versatile search qualifiers, global changes, conditionals, online help, hexadecimal mode, space compression, looping, logical combinations of search strings, journaling, visible control characters, and automatic detabbing. Users of Cambridge implementation devised such ZED procedures as chess games, calculators, and programs for evaluating pi. Written entirely in C.

  13. Gamma-Ray Line Astronomy

    OpenAIRE

    Diehl, Roland

    2004-01-01

    Gamma-ray lines from radioactive isotopes, ejected into interstellar space by cosmic nucleosynthesis events, are observed with new space telescopes. The Compton Observatory had provided a sky survey for the isotopes 56Co, 22Na, 44Ti, and 26Al, detecting supernova radioactivity and the diffuse glow of long-lived radioactivity from massive stars in the Galaxy. High-resolution spectroscopy is now being exploited with Ge detectors: Since 2002, with ESA's INTEGRAL satellite and the RHESSI solar im...

  14. Solid mechanics a variational approach

    CERN Document Server

    Dym, Clive L

    2013-01-01

    Solid Mechanics: A Variational Approach, Augmented Edition presents a lucid and thoroughly developed approach to solid mechanics for students engaged in the study of elastic structures not seen in other texts currently on the market. This work offers a clear and carefully prepared exposition of variational techniques as they are applied to solid mechanics. Unlike other books in this field, Dym and Shames treat all the necessary theory needed for the study of solid mechanics and include extensive applications. Of particular note is the variational approach used in developing consistent structural theories and in obtaining exact and approximate solutions for many problems.  Based on both semester and year-long courses taught to undergraduate seniors and graduate students, this text is geared for programs in aeronautical, civil, and mechanical engineering, and in engineering science. The authors’ objective is two-fold: first, to introduce the student to the theory of structures (one- and two-dimensional) as ...

  15. Variational methods in molecular modeling

    CERN Document Server

    2017-01-01

    This book presents tutorial overviews for many applications of variational methods to molecular modeling. Topics discussed include the Gibbs-Bogoliubov-Feynman variational principle, square-gradient models, classical density functional theories, self-consistent-field theories, phase-field methods, Ginzburg-Landau and Helfrich-type phenomenological models, dynamical density functional theory, and variational Monte Carlo methods. Illustrative examples are given to facilitate understanding of the basic concepts and quantitative prediction of the properties and rich behavior of diverse many-body systems ranging from inhomogeneous fluids, electrolytes and ionic liquids in micropores, colloidal dispersions, liquid crystals, polymer blends, lipid membranes, microemulsions, magnetic materials and high-temperature superconductors. All chapters are written by leading experts in the field and illustrated with tutorial examples for their practical applications to specific subjects. With emphasis placed on physical unders...

  16. Variation in gene expression within clones of the earthworm Dendrobaena octaedra.

    Directory of Open Access Journals (Sweden)

    Marina Mustonen

    Full Text Available Gene expression is highly plastic, which can help organisms to both acclimate and adapt to changing environments. Possible variation in gene expression among individuals with the same genotype (among clones is not widely considered, even though it could impact the results of studies that focus on gene expression phenotypes, for example studies using clonal lines. We examined the extent of within and between clone variation in gene expression in the earthworm Dendrobaena octaedra, which reproduces through apomictic parthenogenesis. Five microsatellite markers were developed and used to confirm that offspring are genetic clones of their parent. After that, expression of 12 genes was measured from five individuals each from six clonal lines after exposure to copper contaminated soil. Variation in gene expression was higher over all genotypes than within genotypes, as initially assumed. A subset of the genes was also examined in the offspring of exposed individuals in two of the clonal lines. In this case, variation in gene expression within genotypes was as high as that observed over all genotypes. One gene in particular (chymotrypsin inhibitor also showed significant differences in the expression levels among genetically identical individuals. Gene expression can vary considerably, and the extent of variation may depend on the genotypes and genes studied. Ensuring a large sample, with many different genotypes, is critical in studies comparing gene expression phenotypes. Researchers should be especially cautious inferring gene expression phenotypes when using only a single clonal or inbred line, since the results might be specific to only certain genotypes.

  17. Magnetic field variations accompanying the filament eruption and the flare related to coronal mass ejections

    Science.gov (United States)

    Fainshtein, V. G.; Egorov, Ya. I.; Rudenko, G. V.; Anfinogentov, S. A.

    2016-12-01

    Field variations in the region of eruptive event of June 7, 2011, associated with the filament eruption (FE), flare, and coronal mass ejection are studied based on vector measurements of the photospheric magnetic field with the SDO/HMI instrument. Variations of the module (B), the radial (Br) and transverse (Bt) components of the magnetic induction, and the inclination angle (α) of field lines to the radial direction from the center of the Sun are analyzed. It is shown that the strongest changes of the field before the event were located near the base of the southeastern leg of the eruptive filament; after the beginning of the event, they were located in the CME flare region. It is suggested that the FE is associated with two episodes of strong and rapid field variations: before the beginning of the slow filament rise and before its sudden acceleration. For the first time, variations of the inclination angles of the field lines over time in different parts of the eruptive event are studied in detail. It was found that the inclination angles of the field lines decrease in the vicinity of its channel during the slow rise of the filament, and the inclination angles of the field lines increase sharply after the beginning of the flare in the flare region in the vicinity of the neutral line.

  18. Associations between Variation in X Chromosome Male Reproductive Genes and Sperm Competitive Ability in Drosophila melanogaster

    Directory of Open Access Journals (Sweden)

    Leah Greenspan

    2011-01-01

    Full Text Available Variation in reproductive success has long been thought to be mediated in part by genes encoding seminal proteins. Here we explore the effect on male reproductive phenotypes of X-linked polymorphisms, a chromosome that is depauperate in genes encoding seminal proteins. Using 57 X chromosome substitution lines, sperm competition was tested both when the males from the wild-extracted line were the first to mate (“defense” crosses, followed by a tester male, and when extracted-line males were the second to mate, after a tester male (“offfense” crosses. We scored the proportion of progeny sired by each male, the fecundity, the remating rate and refractoriness to remating, and tested the significance of variation among lines. Eleven candidate genes were chosen based on previous studies, and portions of these genes were sequenced in all 57 lines. A total of 131 polymorphisms were tested for associations with the reproductive phenotypes using linear models. Nine polymorphisms in 4 genes were found to show significant associations (at a 5% FDR. Overall, it appears that the X chromosomes harbor abundant variation in sperm competition, especially considering the paucity of seminal protein genes. This suggests that much of the male reproductive variation lies outside of genes that encode seminal proteins.

  19. Workshop on Radio Recombination Lines

    CERN Document Server

    1980-01-01

    Since their first detection 15 years ago, radio recombination lines from several elements have been observed in a wide variety of objects including HII regions, planetary nebulae, molecular clouds, the diffuse interstellar medium, and recently, other galaxies. The observations span almost the entire range from 0.1 to 100 GHz, and employ both single­ djsh and aperture synthesis techniques. The theory of radio recombination lines has also advanced strongly, to the point where it is perhaps one of the best-understood in astro­ physics. In a parallel development, it has become possible over the last decade to study these same highly-excited atoms in the laboratory; this work provides further confirmation of the theoretical framework. However there has been continuing controversy over the astrophysical interpre­ tation of radio recombination line observations, especially regarding the role of stimulated emission. A workshop was held in Ottawa on 24-25 August, 1979, bringing together many of the active scientist...

  20. Managing SEMP on-line

    Energy Technology Data Exchange (ETDEWEB)

    Watson, L.E.; Luppens, J.C. [Phillips Petroleum, Lafayette, LA (United States); Johnson, S.T. [M and H Enterprises, Inc., Lafayette, LA (United States)

    1998-12-31

    The North America Production Division of Phillips Petroleum Company has teamed with M and H Enterprises to provide its operators, technicians, engineers and management on-line access and control of the change process and the extensive documentation involved in compliance with API RP 75 Safety and Environmental Management Program (SEMP). M and H Enterprises developed the WinPSM/SEMP{trademark} software and customized it to meet Phillips` SEMP policies and software standards. WinPSM/SEMP is a Windows based client server application, which features the use of a state of the art document management software technology. This system addresses all the elements of SEMP with the all important Management of Change module as a cornerstone component to the program. This paper presents the benefits of an on-line system over the traditional paper based system to control documentation resulting from SEMP compliance. It will demonstrate how this solution has resulted in a streamlined management of change process, safety training has become more current, and safety related procedures have become more accessible to the employees and better documented for compliance reporting purposes. The paper will point out the effectiveness of integrating all elements of SEMP into a single software product, taking advantage of familiar workplace environments to speed up the learning curve for field personnel. It will also address the flexibility of using such a system to include other on-line applications that have similar database accessibility requirements between the field and the supporting office.

  1. Storm surge variational assimilation model

    Directory of Open Access Journals (Sweden)

    Shi-li HUANG

    2010-06-01

    Full Text Available To eliminate errors caused by uncertainty of parameters and further improve capability of storm surge forecasting, the variational data assimilation method is applied to the storm surge model based on unstructured grid with high spatial resolution. The method can effectively improve the forecasting accuracy of storm surge induced by typhoon through controlling wind drag force coefficient parameter. The model is first theoretically validated with synthetic data. Then, the real storm surge process induced by the TC 0515 typhoon is forecasted by the variational data assimilation model, and results show the feasibility of practical application.

  2. Variations autour d’un crime

    Directory of Open Access Journals (Sweden)

    Thanh-Vân Ton-That

    1999-01-01

    Full Text Available À partir d’une lecture des Châtiments et d’autres textes en prose autour du même thème, nous étudierons les variations de genres et d’écritures de Hugo qui en prose comme en poésie entend dénoncer et émouvoir. L’écriture semble dépasser les cloisonnements génériques et formels dans une prose aux inflexions poétiques et dans des vers où se mêlent narration, description et condamnation d’un crime qui prend alors une valeur universelle.On the basis of the reading of Les Châtiments and other prose texts centered on the same theme, we shall study Hugo’s genre and writing variations. In prose as well as in poetry, he intends to expose and to move. The way in which he writes seems to defy formal and generic classifications through a form of prose which is characterized by poetic overtones, and in lines in which narration and description intermingle with the exposition of a crime which takes on a universal meaning.A partir de una lectura de Châtiments y otros textos en prosa sobre el mismo tema, estudiaremos las variaciones de géneros y escrituras en Hugo quien, en prosa como en poesίa, pretende denunciar y conmover. La escritura parece superar las fronteras genéricas y formales en una prosa llena de inflexiones poéticas y en versos en los que se mezclan narración, descripción y condenación de un crimen que se viste por ende de un valor universal.

  3. Compensation of 110 kV Cable Lines – Possibilities and Limitations

    Directory of Open Access Journals (Sweden)

    Piotr Kacejko

    2015-09-01

    Full Text Available This paper discusses problems of the compensation of 110 kV cable lines tens of kilometres long. Such lines are currently built primarily to connect a wind farm, as a consequence of the difficulties in obtaining permits for overhead line construction. Practical design problems derive from the fact of an undetermined cable capacitance and choke reactance (individually manufactured custom devices and the voltage variation at the interconnection point. With a probabilistic approach possible solutions are suggested for selecting compensation devices.

  4. Linewidth statistics of single InGaAs quantum dot photolumincescence lines

    DEFF Research Database (Denmark)

    Leosson, Kristjan; Jensen, Jacob Riis; Hvam, Jørn Märcher

    2000-01-01

    of linewidths is not significantly influenced by small variations in the quantum dot confinement potential. We claim that the wider transition lines are broadened by local electric field fluctuations while narrower lines are homogeneously broadened by acoustic-phonon interactions. The width of narrow single......We have used photoluminescence spectroscopy with high spatial and spectral resolution to measure the linewidths of single emission lines from In0.5Ga0.5As/GaAs self-assembled quantum dots. At 10 K, we find a broad, asymmetric distribution of linewidths with a maximum at 50 mu eV. The distribution...

  5. Short-line matching networks for circulators and resonant loads

    Science.gov (United States)

    Levy, R.; Helszajn, J.

    1983-10-01

    An important load circuit encountered in the synthesis of microwave components is a simple parallel RLC network. Replacing the lumped elements by short stubs permits an exact synthesis using relatively short commensurate transmission lines. The synthesis is given for the general case in terms of the maximum and minimum values of passband-reflection coefficients, commensurate electrical length, and bandwidth. Varying either the level of the minima, the basic commensurate electrical length, or both, allows significant variation in the impedance levels of the load circuit to be accommodated. A practical application involving a junction circulator is described.

  6. Effects of teicoplanin on cell number of cultured cell lines

    Directory of Open Access Journals (Sweden)

    Kashkolinejad-Koohi Tahere

    2015-03-01

    Full Text Available Teicoplanin is a glycopeptide antibiotic with a wide variation in human serum half-life. It is also a valuable alternative of vancomycin. There is however no study on its effect on cultured cells. The aim of the present study was to test the effect of teicoplanin on cultured cell lines CHO, Jurkat E6.1 and MCF-7. The cultured cells were exposed to teicoplanin at final concentrations of 0–11000 μg/ml for 24 hours. To determine cell viability, the 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT test was performed. At low concentrations of teicoplanin the numbers of cultured cells (due to cell proliferation were increased in the three cell lines examined. The maximum cell proliferation rates were observed at concentrations of 1000, 400, and 200 μg/ml of teicoplanin for CHO, MCF-7 and Jurkat cell lines, respectively. Cell toxicity was observed at final concentrations over 2000, 6000, and 400 μg/ml of teicoplanin for CHO, MCF-7 and Jurkat cell lines, respectively. A dose-dependent manner of cell toxicity was observed. Our present findings indicated that teicoplanin at clinically used concentrations induced cell proliferation. It should therefore be used cautiously, particularly in children, pregnant women and patients with cancer.

  7. Genetic and molecular dissection of naturally occurring variations in rice

    Energy Technology Data Exchange (ETDEWEB)

    Yano, Masahiro [National Institute of Agrobiological Sciences, Tsukuba, Ibaraki (Japan)

    2002-02-01

    The progress for structural analysis of the rice genome has allowed us to embark on the sequencing of the whole rice genome. Resources - genetic markers, sequence data, and genomic clones - derived from many efforts will be used for the functional analysis of rice genes in the next decade. Although artificially induced variations, such as mutants, have been used mainly for genetic and physiological studies in rice and other plant species, the development of DNA markers has made possible access to naturally occurring allelic variations underlying complex traits. Such analysis is often referred to as quantitative traits locus (QTL) analysis. Many QTLs have been mapped for many complex traits in rice. During the analyses of several quantitative traits by the DNA marker-assisted strategy, two questions about QTL analysis have been raised: 1) Does a QTL represent a single Mendelian locus or a cluster of multiple loci? 2) Is it possible to precisely map a QTL and identify QTLs at the molecular level using map-based or other strategies? To answer these questions, a series of analyses on heading date, including the identification of putative QTLs, characterization and fine mapping of QTLs using nearly isogenic lines (NILs), and identification of genes at QTLs for heading date by the map-based strategy has been performed. In addition, several primary permanent mapping populations and secondary genetic resources, such as chromosomal segmental substitution lines, have been developed to facilitate the genetic analysis of naturally occurring allelic variation. (M. Suetake)

  8. Age-Specific Variation in Immune Response in Drosophila melanogaster Has a Genetic Basis

    Science.gov (United States)

    Felix, Tashauna M.; Hughes, Kimberly A.; Stone, Eric A.; Drnevich, Jenny M.; Leips, Jeff

    2012-01-01

    Immunosenescence, the age-related decline in immune system function, is a general hallmark of aging. While much is known about the cellular and physiological changes that accompany immunosenescence, we know little about the genetic influences on this phenomenon. In this study we combined age-specific measurements of bacterial clearance ability following infection with whole-genome measurements of the transcriptional response to infection and wounding to identify genes that contribute to the natural variation in immunosenescence, using Drosophila melanogaster as a model system. Twenty inbred lines derived from nature were measured for their ability to clear an Escherichia coli infection at 1 and 4 weeks of age. We used microarrays to simultaneously determine genome-wide expression profiles in infected and wounded flies at each age for 12 of these lines. Lines exhibited significant genetically based variation in bacterial clearance at both ages; however, the genetic basis of this variation changed dramatically with age. Variation in gene expression was significantly correlated with bacterial clearance ability only in the older age group. At 4 weeks of age variation in the expression of 247 genes following infection was associated with genetic variation in bacterial clearance. Functional annotation analyses implicate genes involved in energy metabolism including those in the insulin signaling/TOR pathway as having significant associations with bacterial clearance in older individuals. Given the evolutionary conservation of the genes involved in energy metabolism, our results could have important implications for understanding immunosenescence in other organisms, including humans. PMID:22554890

  9. Functional diversity of the lateral line system among populations of a native Australian freshwater fish.

    Science.gov (United States)

    Spiller, Lindsey; Grierson, Pauline F; Davies, Peter M; Hemmi, Jan; Collin, Shaun P; Kelley, Jennifer L

    2017-06-15

    Fishes use their mechanoreceptive lateral line system to sense nearby objects by detecting slight fluctuations in hydrodynamic motion within their immediate environment. Species of fish from different habitats often display specialisations of the lateral line system, in particular the distribution and abundance of neuromasts, but the lateral line can also exhibit considerable diversity within a species. Here, we provide the first investigation of the lateral line system of the Australian western rainbowfish ( Melanotaenia australis ), a species that occupies a diversity of freshwater habitats across semi-arid northwest Australia. We collected 155 individuals from eight populations and surveyed each habitat for environmental factors that may contribute to lateral line specialisation, including water flow, predation risk, habitat structure and prey availability. Scanning electron microscopy and fluorescent dye labelling were used to describe the lateral line system in M. australis , and to examine whether the abundance and arrangement of superficial neuromasts (SNs) varied within and among populations. We found that the SNs of M. australis were present in distinct body regions rather than lines. The abundance of SNs within each body region was highly variable, and also differed among populations and individuals. Variation in SN abundance among populations was best explained by habitat structure and the availability of invertebrate prey. Our finding that specific environmental factors explain among-population variation in a key sensory system suggests that the ability to acquire sensory information is specialised for the particular behavioural needs of the animal. © 2017. Published by The Company of Biologists Ltd.

  10. Discovery of Scattering Polarization in the Hydrogen Ly α Line of the Solar Disk Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Kano, R.; Narukage, N.; Ishikawa, R.; Bando, T.; Katsukawa, Y.; Kubo, M.; Giono, G.; Hara, H.; Suematsu, Y. [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Bueno, J. Trujillo [Instituto de Astrofísica de Canarias, La Laguna, Tenerife, E-38205 (Spain); Winebarger, A.; Kobayashi, K. [Marshall Space Flight Center, National Aeronautics and Space Administration (NASA), Huntsville, AL 35812 (United States); Auchère, F. [Institut d’Astrophysique Spatiale, Université Paris Sud, Batiment 121, F-91405 Orsay (France); Ishikawa, S.; Shimizu, T.; Sakao, T.; Tsuneta, S. [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 3-1-1 Yoshinodai, Chuo, Sagamihara, Kanagawa 252-5210 (Japan); Ichimoto, K. [Hida Observatory, Kyoto University, Takayama, Gifu 506-1314 (Japan); Goto, M. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Belluzzi, L., E-mail: ryouhei.kano@nao.ac.jp [Istituto Ricerche Solari Locarno, CH-6605 Locarno Monti (Switzerland); and others

    2017-04-10

    There is a thin transition region (TR) in the solar atmosphere where the temperature rises from 10,000 K in the chromosphere to millions of degrees in the corona. Little is known about the mechanisms that dominate this enigmatic region other than the magnetic field plays a key role. The magnetism of the TR can only be detected by polarimetric measurements of a few ultraviolet (UV) spectral lines, the Ly α line of neutral hydrogen at 121.6 nm (the strongest line of the solar UV spectrum) being of particular interest given its sensitivity to the Hanle effect (the magnetic-field-induced modification of the scattering line polarization). We report the discovery of linear polarization produced by scattering processes in the Ly α line, obtained with the Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP) rocket experiment. The Stokes profiles observed by CLASP in quiet regions of the solar disk show that the Q / I and U / I linear polarization signals are of the order of 0.1% in the line core and up to a few percent in the nearby wings, and that both have conspicuous spatial variations with scales of ∼10 arcsec. These observations help constrain theoretical models of the chromosphere–corona TR and extrapolations of the magnetic field from photospheric magnetograms. In fact, the observed spatial variation from disk to limb of polarization at the line core and wings already challenge the predictions from three-dimensional magnetohydrodynamical models of the upper solar chromosphere.

  11. On Estimation of Contamination from Hydrogen Cyanide in Carbon Monoxide Line-intensity Mapping

    Science.gov (United States)

    Chung, Dongwoo T.; Li, Tony Y.; Viero, Marco P.; Church, Sarah E.; Wechsler, Risa H.

    2017-09-01

    Line-intensity mapping surveys probe large-scale structure through spatial variations in molecular line emission from a population of unresolved cosmological sources. Future such surveys of carbon monoxide line emission, specifically the CO(1-0) line, face potential contamination from a disjointed population of sources emitting in a hydrogen cyanide emission line, HCN(1-0). This paper explores the potential range of the strength of HCN emission and its effect on the CO auto power spectrum, using simulations with an empirical model of the CO/HCN-halo connection. We find that effects on the observed CO power spectrum depend on modeling assumptions but are very small for our fiducial model, which is based on current understanding of the galaxy-halo connection. Given the fiducial model, we expect the bias in overall CO detection significance due to HCN to be less than 1%.

  12. Sequential buckling : a variational analysis

    NARCIS (Netherlands)

    M.A. Peletier (Mark)

    1999-01-01

    textabstractWe examine a variational problem from elastic stability theory: a thin elastic strut on an elastic foundation. The strut has infinite length, and its lateral deflection is represented by $u:RtoR$. Deformation takes place under conditions of prescribed total shortening, leading to the

  13. linking genetic to phenotypic variation

    Indian Academy of Sciences (India)

    Unknown

    phenotypic variation. SHAMPA GHOSH and N. SHARMILA BHARATHI. Evolutionary Biology Laboratory, Evolutionary and Organismal Biology Unit, Jawaharlal Nehru Centre for. Advanced Scientific Research, P.O. Box 6436, Jakkur, Bangalore 560 064, India. Immunity can be classified into two types, namely innate.

  14. Evolutionary significance of epigenetic variation

    NARCIS (Netherlands)

    Richards, C.L.; Verhoeven, K.J.F.; Bossdorf, O.; Wendel, J.F.; Greilhuber, J.; Dolezel, J.; Leitch, I.J.

    2012-01-01

    Several chapters in this volume demonstrate how epigenetic work at the molecular level over the last few decades has revolutionized our understanding of genome function and developmental biology. However, epigenetic processes not only further our understanding of variation and regulation at the

  15. On quadratic variation of martingales

    Indian Academy of Sciences (India)

    ... Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 3. On Quadratic Variation of Martingales. Rajeeva L Karandikar B V Rao. Volume 124 Issue 3 August 2014 pp 457-469 ...

  16. Sea level and climate variations

    NARCIS (Netherlands)

    Oerlemans, J.

    1985-01-01

    Review paper, ESA Symposium on Application of Satellite Data to Climate Modelling. Alpbach (Austria) Sea level is an essential component of the climate system, on which many human activities in the coastal zone depend. Climate variations leading to changes in relative sea level are

  17. Separating common from distinctive variation

    NARCIS (Netherlands)

    van der Kloet, F.M.; Sebastián-León, P.; Conesa, A.; Smilde, A.K.; Westerhuis, J.A.

    2016-01-01

    BACKGROUND: Joint and individual variation explained (JIVE), distinct and common simultaneous component analysis (DISCO) and O2-PLS, a two-block (X-Y) latent variable regression method with an integral OSC filter can all be used for the integrated analysis of multiple data sets and decompose them in

  18. Community LINE Source Model (C-LINE) | Science Inventory ...

    Science.gov (United States)

    This presentation provides an introduction for the live demo and explains the purpose of C-LINE and its key features. C-LINE is a web-based model designed to inform the community user of local air quality impacts due to mobile-sources in their region of interest using a simplified modeling approach. It is designed for examining what-if scenarios of changes in emissions, such as those due to changes in traffic volume, fleet mix, or vehicle speed. The model is not intended to be used for any regulatory, enforcement or permitting decisions. The National Exposure Research Laboratory (NERL) Computational Exposure Division (CED) develops and evaluates data, decision-support tools, and models to be applied to media-specific or receptor-specific problem areas. CED uses modeling-based approaches to characterize exposures, evaluate fate and transport, and support environmental diagnostics/forensics with input from multiple data sources. It also develops media- and receptor-specific models, process models, and decision support tools for use both within and outside of EPA.

  19. 49 CFR 192.707 - Line markers for mains and transmission lines.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Line markers for mains and transmission lines. 192... § 192.707 Line markers for mains and transmission lines. (a) Buried pipelines. Except as provided in... buried main and transmission line: (1) At each crossing of a public road and railroad; and (2) Wherever...

  20. McMurray's Test and Joint Line Tenderness for Medial Meniscus ...

    African Journals Online (AJOL)

    BACKGROUND: Meniscus tears are the most common injury of the knee. The McMurray's test and Joint line tenderness for diagnosing meniscus tear have been widely tested, but results reported by different authors vary. The wide variations reported have an impact on clinical decision concerning whether to go for other ...

  1. Feature-based product line instantiation using source-level packages

    NARCIS (Netherlands)

    A. van Deursen (Arie); M. de Jonge (Merijn); T. Kuipers (Tobias)

    2002-01-01

    textabstractIn this paper we discuss the construction of software products from customer-specific feature selections. We address variability management with the Feature Description Language (FDL) to capture variation points of product line architectures. We describe feature packaging which covers

  2. On-line trigger processor in PETRA/DORIS experiments at DESY

    CERN Document Server

    ölschläger, R

    1981-01-01

    Data, presented at a poster session, on on-line trigger processing are given. Brief details of trigger processors at the detectors CELLO, TASSO and ARAUS are shown, including: general working method; IC technology; power consumption; logic elements for trigger decision; number of chambers; number of input wires; execution time; parameter variation; links to host computer; cost; test features. (0 refs).

  3. The non-LTE formation of Li I lines in cool stars

    NARCIS (Netherlands)

    Carlsson, M.; Rutten, R.J.; Bruls, J.H.M.J.; Shchukina, N. G.

    1994-01-01

    We study the non-LTE (non local thermodynamic equilibrium) formation of Li I lines in the spectra of cool stars for a grid of radiative-equilibrium model atmospheres with variation in effective temperature, gravity, metallicity and lithium abundance. We analyze the mechanisms by which departures

  4. Optimization of C5+ Balmer-α line intensity at 182 Å from laser ...

    Indian Academy of Sciences (India)

    detector side. The height of this slit was kept long ~20 mm, so that it allows all the diffracted rays to pass through it. A spatial resolution of ~250 µm was available with this configuration. We have used this mode to study the axial variation of. Balmer-α 182 Å C5+ line intensity in the direction of the target normal (which.

  5. Exploring the power of rice (O. sativa x O. rufipogon) chromosome segment substitution line libraries

    Science.gov (United States)

    Transgressive variation was reported as an increase in grain yield for several rice (Oryza sativa x O. rufipogon) advanced backcross mapping populations. The objective of this study was to develop chromosome segment substitution line (CSSL) libraries to further dissect the reported transgressive var...

  6. Physiological and molecular analysis of selected Kenyan maize lines for aluminum tolerance

    Science.gov (United States)

    Aluminum (Al) toxicity is an important limitation to maize production in many tropical and sub-tropical acid soil areas. The aim of this study was to survey the variation in Al tolerance in a panel of maize lines adapted for Kenya and look for novel sources of Al tolerance. 112 Kenyan maize accessio...

  7. Stage-specific effects of candidate heterochronic genes on variation in developmental time along an altitudinal cline of Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Julián Mensch

    Full Text Available BACKGROUND: Previously, we have shown there is clinal variation for egg-to-adult developmental time along geographic gradients in Drosophila melanogaster. Further, we also have identified mutations in genes involved in metabolic and neurogenic pathways that affect development time (heterochronic genes. However, we do not know whether these loci affect variation in developmental time in natural populations. METHODOLOGY/PRINCIPAL FINDINGS: Here, we constructed second chromosome substitution lines from natural populations of Drosophila melanogaster from an altitudinal cline, and measured egg-adult development time for each line. We found not only a large amount of genetic variation for developmental time, but also positive associations of the development time with thermal amplitude and altitude. We performed genetic complementation tests using substitution lines with the longest and shortest developmental times and heterochronic mutations. We identified segregating variation for neurogenic and metabolic genes that largely affected the duration of the larval stages but had no impact on the timing of metamorphosis. CONCLUSIONS/SIGNIFICANCE: Altitudinal clinal variation in developmental time for natural chromosome substitution lines provides a unique opportunity to dissect the response of heterochronic genes to environmental gradients. Ontogenetic stage-specific variation in invected, mastermind, cricklet and CG14591 may affect natural variation in development time and thermal evolution.

  8. Integrated Glass Coating Manufacturing Line

    Energy Technology Data Exchange (ETDEWEB)

    Brophy, Brenor [Enki Technology Inc., San Jose, CA (United States)

    2015-09-30

    This project aims to enable US module manufacturers to coat glass with Enki’s state of the art tunable functionalized AR coatings at the lowest possible cost and highest possible performance by encapsulating Enki’s coating process in an integrated tool that facilitates effective process improvement through metrology and data analysis for greater quality and performance while reducing footprint, operating and capital costs. The Phase 1 objective was a fully designed manufacturing line, including fully specified equipment ready for issue of purchase requisitions; a detailed economic justification based on market prices at the end of Phase 1 and projected manufacturing costs and a detailed deployment plan for the equipment.

  9. The Haptic Lines of Homeland

    Science.gov (United States)

    Dawson, P.; Takatsuka, M.

    2013-02-01

    This paper discusses the conceptual underpinnings, working processes and the tools used for preparing the scene files of a holographic art work which offers a subjective view point on the idea of homeland. The art work, Homeland, an optically formed fringe digital hologram, which is contextualized by the holographic maps used in situational awareness, indicates its subjectivity by strongly referencing the human body, particularly the lines of the palm of the hand. ... because the body belongs to the order of things as the world is universal flesh. Maurice Merleau-Ponty

  10. A contrario line segment detection

    CERN Document Server

    von Gioi, Rafael Grompone

    2014-01-01

    The reliable detection of low-level image structures is an old and still challenging problem in computer vision. This?book leads a detailed tour through the LSD algorithm, a line segment detector designed to be fully automatic. Based on the a contrario framework, the algorithm works efficiently without the need of any parameter tuning. The design criteria are thoroughly explained and the algorithm's good and bad results are illustrated on real and synthetic images. The issues involved, as well as the strategies used, are common to many geometrical structure detection problems and some possible

  11. The appearance of beam lines

    Energy Technology Data Exchange (ETDEWEB)

    Carey, D.C.

    1993-05-01

    The combination of an existing graphics package with a large program like TRANSPORT has often resulted in considerable modification to the large program. Use of other graphics package has resulted in essentially having to repeat the work. This difficulty has been avoided in a modification of TRANSPORT which produce layouts of beam lines. Drawings of the reference trajectory and three-dimensional images of all magnets are made by the graphics package TOP DRAWER. Nothing specific to TOP DRAWER or any other graphics has been incorporated into TRANSPORT. If a user is with a different graphics package he or she can then begin usage of this alternate package essentially immediately.

  12. Understanding broadband over power line

    CERN Document Server

    Held, Gilbert

    2006-01-01

    Understanding Broadband over Power Line explores all aspects of the emerging technology that enables electric utilities to provide support for high-speed data communications via their power infrastructure. This book examines the two methods used to connect consumers and businesses to the Internet through the utility infrastructure: the existing electrical wiring of a home or office; and a wireless local area network (WLAN) access point.Written in a practical style that can be understood by network engineers and non-technologists alike, this volume offers tutorials on electric utility infrastru

  13. The Astrophysics of Emission-Line Stars

    CERN Document Server

    Kogure, Tomokazu

    2007-01-01

    Many types of stars show conspicuous emission lines in their optical spectra. These stars are broadly referred to as emission line stars. Emission line stars are attractive to many people because of their spectacular phenomena and their variability. The Astrophysics of Emission Line Stars offers general information on emission line stars, starting from a brief introduction to stellar astrophysics, and then moving toward a broad overview of emission line stars including early and late type stars as well as pre-main sequence stars. Detailed references have been prepared along with an index for further reading.

  14. Composite Based EHV AC Overhead Transmission Lines

    DEFF Research Database (Denmark)

    Sørensen, Thomas Kjærsgaard

    Overhead lines at transmission level are the backbone of any national power grid today. New overhead line projects however are at the same time subject to ever greater public resistance due to the lines environmental impact. As full undergrounding of transmission lines at extra high voltage (EHV...... and analysed with regard to the possibilities, limitations and risks widespread application of composite materials on EHV AC overhead transmission lines may present. To form the basis for evaluation of the useability of composite materials, dierent overhead line projects aimed at reducing the environmental...

  15. Variational principles for stochastic soliton dynamics

    Science.gov (United States)

    Holm, Darryl D.; Tyranowski, Tomasz M.

    2016-01-01

    We develop a variational method of deriving stochastic partial differential equations whose solutions follow the flow of a stochastic vector field. As an example in one spatial dimension, we numerically simulate singular solutions (peakons) of the stochastically perturbed Camassa–Holm (CH) equation derived using this method. These numerical simulations show that peakon soliton solutions of the stochastically perturbed CH equation persist and provide an interesting laboratory for investigating the sensitivity and accuracy of adding stochasticity to finite dimensional solutions of stochastic partial differential equations. In particular, some choices of stochastic perturbations of the peakon dynamics by Wiener noise (canonical Hamiltonian stochastic deformations, CH-SD) allow peakons to interpenetrate and exchange order on the real line in overtaking collisions, although this behaviour does not occur for other choices of stochastic perturbations which preserve the Euler–Poincaré structure of the CH equation (parametric stochastic deformations, P-SD), and it also does not occur for peakon solutions of the unperturbed deterministic CH equation. The discussion raises issues about the science of stochastic deformations of finite-dimensional approximations of evolutionary partial differential equation and the sensitivity of the resulting solutions to the choices made in stochastic modelling. PMID:27118922

  16. Grism-based pulse shaper for line-by-line control of more than 600 optical frequency comb lines.

    Science.gov (United States)

    Kirchner, M S; Diddams, S A

    2010-10-01

    We construct a line-by-line pulse shaper using a grism (grating plus prism) dispersive element, which provides constant angular dispersion over 13.4 THz centered at ~311 THz (965 nm). When combined with a dual-mask liquid crystal modulator, this grism-based shaper is capable of line-by-line amplitude and phase control of over 600 modes of a 21 GHz stabilized optical frequency comb.

  17. Genetically and environmentally mediated divergence in lateral line morphology in the Trinidadian guppy (Poecilia reticulata).

    Science.gov (United States)

    Fischer, Eva K; Soares, Daphne; Archer, Kathryn R; Ghalambor, Cameron K; Hoke, Kim L

    2013-08-15

    Fish and other aquatic vertebrates use their mechanosensory lateral line to detect objects and motion in their immediate environment. Differences in lateral line morphology have been extensively characterized among species; however, intraspecific variation remains largely unexplored. In addition, little is known about how environmental factors modify development of lateral line morphology. Predation is one environmental factor that can act both as a selective pressure causing genetic differences between populations, and as a cue during development to induce plastic changes. Here, we test whether variation in the risk of predation within and among populations of Trinidadian guppies (Poecilia reticulata) influences lateral line morphology. We compared neuromast arrangement in wild-caught guppies from distinct high- and low-predation population pairs to examine patterns associated with differences in predation pressure. To distinguish genetic and environmental influences, we compared neuromast arrangement in guppies from different source populations reared with and without exposure to predator chemical cues. We found that the distribution of neuromasts across the body varies between populations based on both genetic and environmental factors. To the best of our knowledge, this study is the first to demonstrate variation in lateral line morphology based on environmental exposure to an ecologically relevant stimulus.

  18. Variation of Parameters in Differential Equations (A Variation in Making Sense of Variation of Parameters)

    Science.gov (United States)

    Quinn, Terry; Rai, Sanjay

    2012-01-01

    The method of variation of parameters can be found in most undergraduate textbooks on differential equations. The method leads to solutions of the non-homogeneous equation of the form y = u[subscript 1]y[subscript 1] + u[subscript 2]y[subscript 2], a sum of function products using solutions to the homogeneous equation y[subscript 1] and…

  19. Cross delay line sensor characterization

    Energy Technology Data Exchange (ETDEWEB)

    Owens, Israel J [Los Alamos National Laboratory; Remelius, Dennis K [Los Alamos National Laboratory; Tiee, Joe J [Los Alamos National Laboratory; Buck, Steven E [Los Alamos National Laboratory; Whittemore, Stephen R [Los Alamos National Laboratory; Thompson, David C [Los Alamos National Laboratory; Shirey, Robert [Los Alamos National Laboratory

    2010-01-01

    There exists a wealth of information in the scientific literature on the physical properties and device characterization procedures for complementary metal oxide semiconductor (CMOS), charge coupled device (CCD) and avalanche photodiode (APD) format detectors. Numerous papers and books have also treated photocathode operation in the context of photomultiplier tube (PMT) operation for either non imaging applications or limited night vision capability. However, much less information has been reported in the literature about the characterization procedures and properties of photocathode detectors with novel cross delay line (XDL) anode structures. These allow one to detect single photons and create images by recording space and time coordinate (X, Y & T) information. In this paper, we report on the physical characteristics and performance of a cross delay line anode sensor with an enhanced near infrared wavelength response photocathode and high dynamic range micro channel plate (MCP) gain (> 10{sup 6}) multiplier stage. Measurement procedures and results including the device dark event rate (DER), pulse height distribution, quantum and electronic device efficiency (QE & DQE) and spatial resolution per effective pixel region in a 25 mm sensor array are presented. The overall knowledge and information obtained from XDL sensor characterization allow us to optimize device performance and assess capability. These device performance properties and capabilities make XDL detectors ideal for remote sensing field applications that require single photon detection, imaging, sub nano-second timing response, high spatial resolution (10's of microns) and large effective image format.

  20. Energetic Variational Approach to Multi-Component Fluid Flows

    Science.gov (United States)

    Kirshtein, Arkadz; Liu, Chun; Brannick, James

    2017-11-01

    In this talk I will introduce the systematic energetic variational approach for dissipative systems applied to multi-component fluid flows. These variational approaches are motivated by the seminal works of Rayleigh and Onsager. The advantage of this approach is that we have to postulate only energy law and some kinematic relations based on fundamental physical principles. The method gives a clear, quick and consistent way to derive the PDE system. I will compare different approaches to three-component flows using diffusive interface method and discuss their advantages and disadvantages. The diffusive interface method is an approach for modeling interactions among complex substances. The main idea behind this method is to introduce phase field labeling functions in order to model the contact line by smooth change from one type of material to another. The work of Arkadz Kirshtein and Chun Liu is partially supported by NSF Grants DMS-141200 and DMS-1216938.

  1. Variation in In Vitro Digestibility of Barley Protein

    DEFF Research Database (Denmark)

    Buchmann, N. B.

    1979-01-01

    In vitro digestibility of protein was measured with pepsin/pancreatin in 321 spring barley lines grown in the field. The variation in digestibility was far less than the variation in the protein content. A small environmental influence on the digestibility was found. Two entries had slightly...... impaired digestibilities; these findings were partially verified in a repeated field trial, but were not confirmed in vivo. In vitro digestibilities of barleys grown in pots at various N-levels were positively correlated with protein or hordein content. In vitro digestibility was negatively correlated...... with the fibre content in decortification fractions of Bomi and the high-lysine mutant Risø 1508. The digestibility was positively correlated with the hordein concentration for the Bomi fractions, but not for the 1508 fractions....

  2. The early period of the calculus of variations

    CERN Document Server

    Freguglia, Paolo

    2016-01-01

    This monograph explores the early development of the calculus of variations in continental Europe during the Eighteenth Century by illustrating the mathematics of its founders. Closely following the original papers and correspondences of Euler, Lagrange, the Bernoullis, and others, the reader is immersed in the challenge of theory building. We see what the founders were doing, the difficulties they faced, the mistakes they made, and their triumphs. The authors guide the reader through these works with instructive commentaries and complements to the original proofs, as well as offering a modern perspective where useful. The authors begin in 1697 with Johann Bernoulli’s work on the brachystochrone problem and the events leading up to it, marking the dawn of the calculus of variations. From there, they cover key advances in the theory up to the development of Lagrange’s δ-calculus, including: • The isoperimetrical problems • Shortest lines and geodesics • Euler’s Methodus Inveniendi and the two Addi...

  3. On Bottleneck Product Rate Variation Problem with Batching

    Directory of Open Access Journals (Sweden)

    Shree Khadka

    2013-07-01

    Full Text Available The product rate variation problem minimizes the variation in the rate at which different models of a common base product are produced on the assembly lines with the assumption of negligible switch-over cost and unit processing time for each copy of each model. The assumption of significant setup and arbitrary processing times forces the problem to be a two phase problem. The first phase determines the size and the number of batches and the second one sequences the batches of models. In this paper, the bottleneck case i.e. the min-max case of the problem with a generalized objective function is formulated. A Pareto optimal solution is proposed and a relation between optimal sequences for the problem with different objective functions is investigated.

  4. Beam line design using G4BeamLine

    CERN Document Server

    Dogan, Arda

    2014-01-01

    In Turkey in Ankara TAEK SANAEM Proton Accelerator Facility (PAF), there is a cyclotron which produces a focused intense 30 MeV proton beam and sends this beam to four different arms, three of which uses this beam to produce pharmaceutical medicine. The remaining one is spared for R&D purposes and the idea was to use these protons coming out from the fourth arm to use space radiation tests, which cannot be done in Turkey at the moment. However, according to SCC 25100 standards which is for 30 MeV protons, the beam coming out of cyclotron is too intense and focused to use for space radiation tests. Therefore, the main aim of my project is to design a beam line which will defocus the beam and reduce the flux so that the space radiation tests can be done according to the standards of SCC 25100.

  5. Robust on-line monitoring of biogas processes; Robusta maettekniker on-line foer optimerad biogasproduktion

    Energy Technology Data Exchange (ETDEWEB)

    Nordberg, Aake; Hansson, Mikael; Kanerot, Mija; Krozer, Anatol; Loefving, Bjoern; Sahlin, Eskil

    2010-03-15

    Although demand for biomethane in Sweden is higher than ever, many Swedish codigestion plants are presently operated below their designed capacity. Efforts must be taken to increase the loading rate and guarantee stable operation and high availability of the plants. There are currently no commercial systems for on-line monitoring, and due to the characteristics of the material, including corrosion and tearing, robust applications have to be developed. The objective of this project was to identify and study different monitoring technologies with potential for on-line monitoring of both substrate mixtures and anaerobic digester content. Based on the prerequisites and demands at Boraas Energi och Miljoe AB's (BEMAB, the municipal energy and waste utility in the city of Boraas, Sweden) biogas plant, the extent of the problems, measurement variables and possible ways of managing these issues have been identified and prioritized. The substrate mixtures in question have a high viscosity and are inhomogeneous with variation in composition, which calls for further homogenization, dilution and filtration to achieve high precision in the necessary analyses. Studies of using different mixers and mills showed that the particle size (800 mum) needed for on-line COD measurement could not be achieved. The problem of homogenization can be avoided if indirect measurement methods are used. Laboratory tests with NIR (near-infra red spectroscopy) showed that VS can be predicted (R2=0,78) in the interval of 2-9% VS. Furthermore, impedance can give a measurement of soluble components. However, impedance is not sensitive enough to give a good measurement of total TS. Microwave technology was installed at the production plant and showed a faster response to changes in TS than the existing TS-sensor. However, due to technical problems, the evaluation only could be done during a limited period of ten days. BEMAB will continue the measurements and evaluation of the instrument. The

  6. Genomics technologies to study structural variations in the grapevine genome

    Directory of Open Access Journals (Sweden)

    Cardone Maria Francesca

    2016-01-01

    Full Text Available Grapevine is one of the most important crop plants in the world. Recently there was great expansion of genomics resources about grapevine genome, thus providing increasing efforts for molecular breeding. Current cultivars display a great level of inter-specific differentiation that needs to be investigated to reach a comprehensive understanding of the genetic basis of phenotypic differences, and to find responsible genes selected by cross breeding programs. While there have been significant advances in resolving the pattern and nature of single nucleotide polymorphisms (SNPs on plant genomes, few data are available on copy number variation (CNV. Furthermore association between structural variations and phenotypes has been described in only a few cases. We combined high throughput biotechnologies and bioinformatics tools, to reveal the first inter-varietal atlas of structural variation (SV for the grapevine genome. We sequenced and compared four table grape cultivars with the Pinot noir inbred line PN40024 genome as the reference. We detected roughly 8% of the grapevine genome affected by genomic variations. Taken into account phenotypic differences existing among the studied varieties we performed comparison of SVs among them and the reference and next we performed an in-depth analysis of gene content of polymorphic regions. This allowed us to identify genes showing differences in copy number as putative functional candidates for important traits in grapevine cultivation.

  7. Susceptibility to keel bone fractures in laying hens and the role of genetic variation.

    Science.gov (United States)

    Candelotto, Laura; Stratmann, Ariane; Gebhardt-Henrich, Sabine G; Rufener, Christina; van de Braak, Teun; Toscano, Michael J

    2017-10-01

    Keel bone fractures are a well-known welfare problem in modern commercial laying hen systems. The present study sought to identify genetic variation in relation to keel bone fracture susceptibility of 4 distinct crossbred and one pure line, and by extension, possible breeding traits. Susceptibility to fractures were assessed using an ex vivo impact testing protocol in combination with a study design that minimized environmental variation to focus on genetic differences. The 5 crossbred/pure lines differed in their susceptibility to keel bone fractures with the greatest likelihood of fracture in one of the 3 commercial lines and the lowest susceptibility to fractures in one of the experimental lines. Egg production at the hen-level did not differ between the crossbred/pure lines (P > 0.05), though an increased susceptibility to keel bone fractures was associated with thinner eggshells and reduced egg breaking strength, a pattern consistent among all tested crossbred/pure lines. Our findings suggest an association between egg quality and bone strength which appeared to be independent of crossbred/pure line. The findings indicate the benefit of the impact methodology to identify potential breeding characteristics to reduce incidence of keel fracture as well as the potential relationship with eggshell quality. © 2017 Poultry Science Association Inc.

  8. RADIAL VELOCITIES OF GALACTIC O-TYPE STARS. II. SINGLE-LINED SPECTROSCOPIC BINARIES

    Energy Technology Data Exchange (ETDEWEB)

    Williams, S. J.; Gies, D. R. [Center for High Angular Resolution Astronomy and Department of Physics and Astronomy, Georgia State University, P.O. Box 4106, Atlanta, GA 30302-4106 (United States); Hillwig, T. C. [Department of Physics and Astronomy, Valparaiso University, Valparaiso, IN 46383 (United States); McSwain, M. V. [Department of Physics, Lehigh University, 16 Memorial Drive East, Bethlehem, PA 18015 (United States); Huang, W., E-mail: swilliams@chara.gsu.edu, E-mail: gies@chara.gsu.edu, E-mail: todd.hillwig@valpo.edu, E-mail: mcswain@lehigh.edu, E-mail: hwenjin@astro.washington.edu [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195-1580 (United States)

    2013-02-01

    We report on new radial velocity measurements of massive stars that are either suspected binaries or lacking prior observations. This is part of a survey to identify and characterize spectroscopic binaries among O-type stars with the goal of comparing the binary fraction of field and runaway stars with those in clusters and associations. We present orbits for HDE 308813, HD 152147, HD 164536, BD-16 Degree-Sign 4826, and HDE 229232, Galactic O-type stars exhibiting single-lined spectroscopic variation. By fitting model spectra to our observed spectra, we obtain estimates for effective temperature, surface gravity, and rotational velocity. We compute orbital periods and velocity semiamplitudes for each system and note the lack of photometric variation for any system. These binaries probably appear single-lined because the companions are faint and because their orbital Doppler shifts are small compared to the width of the rotationally broadened lines of the primary.

  9. Cluster variational theory of spin ((3)/(2)) Ising models

    CERN Document Server

    Tucker, J W

    2000-01-01

    A cluster variational method for spin ((3)/(2)) Ising models on regular lattices is presented that leads to results that are exact for Bethe lattices of the same coordination number. The method is applied to both the Blume-Capel (BC) and the isotropic Blume-Emery-Griffiths model (BEG). In particular, the first-order phase line separating the two low-temperature ferromagnetic phases in the BC model, and the ferrimagnetic phase boundary in the BEG model are studied. Results are compared with those of other theories whose qualitative predictions have been in conflict.

  10. Minimizing Variation in Outdoor CPV Power Ratings: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Muller, M.; Marion, B.; Rodriguez, J.; Kurtz, S.

    2011-07-01

    The CPV community has agreed to have both indoor and outdoor power ratings at the module level. The indoor rating provides a repeatable measure of module performance as it leaves the factory line while the outdoor rating provides a measure of true performance under real world conditions. The challenge with an outdoor rating is that the spectrum, temperature, wind speed, etc are constantly in flux and therefore the resulting power rating varies from day to day and month to month. This work examines different methodologies for determining the outdoor power rating with the goal of minimizing variation even if data are collected under changing meteorological conditions.

  11. Variation in armour of three-spine stickleback

    OpenAIRE

    Wiig, Elisabeth

    2014-01-01

    The three-spine stickleback is an adaptable fish with variation in morphology and behaviour, inhabiting saltwater, brackish water and fresh water. It is armoured with 30-35 bone plates along its lateral line. In addition, it is equipped with three spines on its back and two pelvic spine. These features constitute an excellent anti-predator defence system. Yet, there is a strong selection for reduction in armour of three-spine stickleback in freshwater stickleback. In this project, the bone st...

  12. Variational approach to thermal masses in compactified models

    Energy Technology Data Exchange (ETDEWEB)

    Dominici, Daniele [Dipartimento di Fisica e Astronomia Università di Firenze and INFN - Sezione di Firenze,Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Roditi, Itzhak [Centro Brasileiro de Pesquisas Físicas - CBPF/MCT,Rua Dr. Xavier Sigaud 150, 22290-180, Rio de Janeiro, RJ (Brazil)

    2015-08-20

    We investigate by means of a variational approach the effective potential of a 5DU(1) scalar model at finite temperature and compactified on S{sup 1} and S{sup 1}/Z{sub 2} as well as the corresponding 4D model obtained through a trivial dimensional reduction. We are particularly interested in the behavior of the thermal masses of the scalar field with respect to the Wilson line phase and the results obtained are compared with those coming from a one-loop effective potential calculation. We also explore the nature of the phase transition.

  13. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster.

    Science.gov (United States)

    Dembeck, Lauren M; Böröczky, Katalin; Huang, Wen; Schal, Coby; Anholt, Robert R H; Mackay, Trudy F C

    2015-11-14

    Insect cuticular hydrocarbons (CHCs) prevent desiccation and serve as chemical signals that mediate social interactions. Drosophila melanogaster CHCs have been studied extensively, but the genetic basis for individual variation in CHC composition is largely unknown. We quantified variation in CHC profiles in the D. melanogaster Genetic Reference Panel (DGRP) and identified novel CHCs. We used principal component (PC) analysis to extract PCs that explain the majority of CHC variation and identified polymorphisms in or near 305 and 173 genes in females and males, respectively, associated with variation in these PCs. In addition, 17 DGRP lines contain the functional Desat2 allele characteristic of African and Caribbean D. melanogaster females (more 5,9-C27:2 and less 7,11-C27:2, female sex pheromone isomers). Disruption of expression of 24 candidate genes affected CHC composition in at least one sex. These genes are associated with fatty acid metabolism and represent mechanistic targets for individual variation in CHC composition.

  14. 2008 TIGER/Line Nationwide Dataset

    Data.gov (United States)

    California Department of Resources — This dataset contains a nationwide build of the 2008 TIGER/Line datasets from the US Census Bureau downloaded in April 2009. The TIGER/Line Shapefiles are an extract...

  15. Variability issues in software product lines

    NARCIS (Netherlands)

    Bosch, J; Florijn, G; Greefhorst, D; Kuusela, J; Obbink, JH; Pohl, K; VanderLinden, F

    2002-01-01

    Software product lines (or system families) have achieved considerable adoption by the software industry. A software product line captures the commonalities between a set of products while providing for the differences. Differences are managed by delaying design decisions, thereby introducing

  16. Basic Stand Alone Carrier Line Items PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Carrier Line Items Public Use Files (PUF) with information from Medicare Carrier claims. The CMS BSA Carrier Line...

  17. Student Peer Evaluated Line Balancing Competition

    National Research Council Canada - National Science Library

    2017-01-01

    The Student Peer Evaluated Line Balancing Competition is a 30-minute in-class problem-based learning experiential exercise that challenges student groups to design a feasible and efficient laptop computer assembly line. Each student...

  18. Electrically Isolating Transmission-Line Driver

    Science.gov (United States)

    Marchman, Robert H.

    1992-01-01

    Proposed optoelectronic coupling circuit used to insert signal in transmission line and to isolate transmission line from ground of circuit in which signal originates. Made from commercially available components, reduces susceptibility to interference along transmission path.

  19. State Wildlife Management Area Public Facilities - lines

    Data.gov (United States)

    Minnesota Department of Natural Resources — This line theme contains facilities and features for WMAs that are best represented as lines. WMAs are part of the Minnesota state recreation system created to...

  20. FB Line Basis for Interim Operation

    Energy Technology Data Exchange (ETDEWEB)

    Shedrow, B.

    1998-10-19

    The safety analysis of the FB-Line Facility indicates that the operation of FB-Line to support the current mission does not present undue risk to the facility and co-located workers, general public, or the environment.

  1. Smart street lights using power line communication

    CSIR Research Space (South Africa)

    Du Toit, P

    2017-09-01

    Full Text Available street light faults with the use of communication over the power line. The developed system communicates over power lines using modified frequency shift keying (FSK) modulation. The system used an LDR (light dependent resistor) based light sensor...

  2. Coarse Grained Exponential Variational Autoencoders

    KAUST Repository

    Sun, Ke

    2017-02-25

    Variational autoencoders (VAE) often use Gaussian or category distribution to model the inference process. This puts a limit on variational learning because this simplified assumption does not match the true posterior distribution, which is usually much more sophisticated. To break this limitation and apply arbitrary parametric distribution during inference, this paper derives a \\\\emph{semi-continuous} latent representation, which approximates a continuous density up to a prescribed precision, and is much easier to analyze than its continuous counterpart because it is fundamentally discrete. We showcase the proposition by applying polynomial exponential family distributions as the posterior, which are universal probability density function generators. Our experimental results show consistent improvements over commonly used VAE models.

  3. Tidal variations of earth rotation

    Science.gov (United States)

    Yoder, C. F.; Williams, J. G.; Parke, M. E.

    1981-01-01

    The periodic variations of the earths' rotation resulting from the tidal deformation of the earth by the sun and moon were rederived including terms with amplitudes of 0.002 millisec and greater. The series applies to the mantle, crust, and oceans which rotate together for characteristic tidal periods; the scaling parameter is the ratio of the fraction of the Love number producing tidal variations in the moment of inertia of the coupled mantle and oceans (k) to the dimensionless polar moment of inertia of the coupled moments (C). The lunar laser ranging data shows that k/C at monthly and fortnightly frequencies equals 0.99 + or - 0.15 and 0.99 + or - 0.20 as compared to the theoretical value of 0.94 + or - 0.04.

  4. Variational approach in transport theory

    Energy Technology Data Exchange (ETDEWEB)

    Panta Pazos, R. [Nucler Engineering Department, UFRGS, Porto-Alegre (Brazil); Tullio de Vilhena, M. [Institute of Mathematics, UFRGS, Porto-Alegre (Brazil)

    2004-07-01

    In this work we present a variational approach to some methods to solve transport problems of neutral particles. We consider a convex domain X (for example the geometry of a slab, or a convex set in the plane, or a convex bounded set in the space) and we use discrete ordinates quadrature to get a system of differential equations derived from the neutron transport equation. The boundary conditions are vacuum for a subset of the boundary, and of specular reflection for the complementary subset of the boundary. Recently some different approximation methods have been presented to solve these transport problems. We introduce in this work the adjoint equations and the conjugate functions obtained by means of the variational approach. First we consider the general formulation, and then some numerical methods such as spherical harmonics and spectral collocation method. (authors)

  5. Bernoulli Variational Problem and Beyond

    KAUST Repository

    Lorz, Alexander

    2013-12-17

    The question of \\'cutting the tail\\' of the solution of an elliptic equation arises naturally in several contexts and leads to a singular perturbation problem under the form of a strong cut-off. We consider both the PDE with a drift and the symmetric case where a variational problem can be stated. It is known that, in both cases, the same critical scale arises for the size of the singular perturbation. More interesting is that in both cases another critical parameter (of order one) arises that decides when the limiting behaviour is non-degenerate. We study both theoretically and numerically the values of this critical parameter and, in the symmetric case, ask if the variational solution leads to the same value as for the maximal solution of the PDE. Finally we propose a weak formulation of the limiting Bernoulli problem which incorporates both Dirichlet and Neumann boundary condition. © 2013 Springer-Verlag Berlin Heidelberg.

  6. Decadal variations in groundwater quality

    DEFF Research Database (Denmark)

    Jessen, Søren; Postma, Dieke; Thorling, Lærke

    2017-01-01

    Twenty-five years of groundwater quality monitoring in a sandy aquifer beneath agricultural fields showed large temporal and spatial variations in major ion groundwater chemistry, which were linked closely to the nitrate (NO3) content of agricultural recharge. Between 1988 and 2013, the NO3 content...... loading. Agriculture thus is an important determinant of major ion groundwater chemistry. Temporal and spatial variations in the groundwater quality were simulated using a 2D reactive transport model, which combined effects of the historical NO3 leaching and denitrification, with dispersive mixing...... into the pristine groundwater residing deeper in the aquifer. Reactant-to-product ratios across reaction fronts are altered by dispersive mixing and transience in reactant input functions. Modelling therefore allowed a direct comparison of observed and simulated ratios of concentrations of NO3 (reactant...

  7. Chemical and mechanical defenses vary among maternal lines and leaf ages in Verbascum thapsus L. (Scrophulariaceae) and reduce palatability to a generalist insect

    National Research Council Canada - National Science Library

    Alba, Christina; Bowers, M Deane; Blumenthal, Dana; Hufbauer, Ruth A

    2014-01-01

    ... (Verbascum thapsus L, Scrophulariaceae) among maternal lines within a population and among leaves within plants, and related this variation to feeding preferences of a generalist herbivore, Trichopulsia ni Hübner...

  8. Chemical and Mechanical Defenses Vary among Maternal Lines and Leaf Ages in Verbascum thapsus L. (Scrophulariaceae) and Reduce Palatability to a Generalist Insect: e104889

    National Research Council Canada - National Science Library

    Christina Alba; M Deane Bowers; Dana Blumenthal; Ruth A Hufbauer

    2014-01-01

    ... (Verbascum thapsus L, Scrophulariaceae) among maternal lines within a population and among leaves within plants, and related this variation to feeding preferences of a generalist herbivore, Trichopulsia ni Hübner...

  9. Diet and diabetes: lines and dots.

    Science.gov (United States)

    Katz, David L

    2014-04-01

    Diabetes, particularly type 2 diabetes, is epidemic in the United States among adults and children alike, and increasingly prevalent around the world. On its current trajectory, the increasing incidence of diabetes has the potential to ravage both public health and economies. There has, however, been evidence for decades that lifestyle has enormous potential to prevent chronic disease, diabetes included. Studies suggest that the combination of tobacco avoidance, routine physical activity, optimal dietary pattern, and weight control could eliminate as much as 80% of all chronic disease, and 90% of cases of diabetes specifically. None of these factors is necessarily easily achieved, but most are simple. Diet, on the other hand, is complex, and arguments abound for competing diets and related health benefits. From an expansive review of relevant literature, the case emerges that the overall theme of optimal eating for human beings is very well established, whereas the case for any given variation on that theme is substantially less so. Once the theme of healthful eating is acknowledged, the challenge shifts to getting there from here. Although much effort focuses on the wholesale conversion of dietary patterns, the introduction or removal of highly nutritious foods can have direct health effects, and potentially reverberate through the diet as well, shifting the quality of the diet and related health effects. Studies demonstrating favorable effects of daily walnut ingestion in diabetes and insulin resistance are profiled as an illustration, and an ongoing study examining the implications of daily walnut ingestion on diet quality and various biometric variables is described. The line between dietary pattern and the epidemiology of diabetes is indelibly established; we must work to connect the dots between here and there.

  10. Molecular dynamics study of the nanosized droplet spreading: The effect of the contact line forces on the kinetic energy dissipation

    Science.gov (United States)

    Yoon, Hong Min; Kondaraju, Sasidhar; Lee, Jung Shin; Suh, Youngho; Lee, Joonho H.; Lee, Joon Sang

    2017-07-01

    Recent studies have revealed that contact line forces play an important role in the droplet spreading process. Despite their significance, the physics related to them has been studied only indirectly and the effect of contact line forces is still being disputed. We performed a molecular dynamics simulation and mimicked the droplet spreading process at the nanoscale. Based on the results of the simulation, the contact line forces were directly calculated. We found that the forces acting on the bulk and the contact line region showed different trends. Distinct positive and negative forces, contact line spreading, and friction forces were observed near the contact line. We also observed a strong dependency of the atomic kinetics in the contact line region on the variations in the contact line forces. The atoms of the liquid in the contact line region lost their kinetic energy due to the contact line friction force and became partially immobile on the solid surface. The results of the current study will be useful for understanding the role of the contact line forces on the kinetic energy dissipation in the contact line region.

  11. Phase variations in Bifidobacterium animalis.

    Science.gov (United States)

    Biavati, B; Crociani, F; Mattarelli, P; Scardovi, V

    1992-07-01

    Strains isolated from rabbit, chicken, and rat feces and from sewage and fermented milk products, all identified as Bifidobacterium animalis, were found to show phase variations in colony appearance and in cellular morphology. The rate of transition in a switching system from opaque to transparent colonies and vice versa was determined. Differences in protein components and in penicillin-binding proteins (PBPs) of the cells from different colony types are shown.

  12. Quadratic Variation by Markov Chains

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Horel, Guillaume

    We introduce a novel estimator of the quadratic variation that is based on the the- ory of Markov chains. The estimator is motivated by some general results concerning filtering contaminated semimartingales. Specifically, we show that filtering can in prin- ciple remove the effects of market......- cal results. The proposed estimator is consistent with a Gaussian limit distribution and we study its properties in simulations and an empirical application....

  13. Realization of intermediate links of line arrangements

    OpenAIRE

    Bodin, Arnaud

    2012-01-01

    We investigate several topological and combinatorial properties of line arrangements. We associate to a line arrangement a link obtained by intersecting the arrangement with some sphere. Several topics are discussed: (a) some link configurations can be realized by complex line arrangements but not by real line arrangements; (b) if we intersect the arrangements with a vertical band instead of a sphere, what link configurations can be obtained? (c) relations between link configurations obtained...

  14. Current and Potential Tree Locations in Tree Line Ecotone of Changbai Mountains, Northeast China: The Controlling Effects of Topography

    Science.gov (United States)

    Zong, Shengwei; Wu, Zhengfang; Xu, Jiawei; Li, Ming; Gao, Xiaofeng; He, Hongshi; Du, Haibo; Wang, Lei

    2014-01-01

    Tree line ecotone in the Changbai Mountains has undergone large changes in the past decades. Tree locations show variations on the four sides of the mountains, especially on the northern and western sides, which has not been fully explained. Previous studies attributed such variations to the variations in temperature. However, in this study, we hypothesized that topographic controls were responsible for causing the variations in the tree locations in tree line ecotone of the Changbai Mountains. To test the hypothesis, we used IKONOS images and WorldView-1 image to identify the tree locations and developed a logistic regression model using topographical variables to identify the dominant controls of the tree locations. The results showed that aspect, wetness, and slope were dominant controls for tree locations on western side of the mountains, whereas altitude, SPI, and aspect were the dominant factors on northern side. The upmost altitude a tree can currently reach was 2140 m asl on the northern side and 2060 m asl on western side. The model predicted results showed that habitats above the current tree line on the both sides were available for trees. Tree recruitments under the current tree line may take advantage of the available habitats at higher elevations based on the current tree location. Our research confirmed the controlling effects of topography on the tree locations in the tree line ecotone of Changbai Mountains and suggested that it was essential to assess the tree response to topography in the research of tree line ecotone. PMID:25170918

  15. Intraspecific variation in Cryptocaryon irritans.

    Science.gov (United States)

    Diggles, B K; Adlard, R D

    1997-01-01

    Intraspecific variation in the ciliate Cryptocaryon irritans was examined using sequences of the first internal transcribed spacer region (ITS-1) of ribosomal DNA (rDNA) combined with developmental and morphological characters. Amplified rDNA sequences consisting of 151 bases of the flanking 18 S and 5.8 S regions, and the entire ITS-1 region (169 or 170 bases), were determined and compared for 16 isolates of C. irritans from Australia, Israel and the USA. There was one variable base between isolates in the 18 S region and 11 variable bases in the ITS-1 region. Despite their similar morphology, significant sequence variation (4.1% divergence) and developmental differences indicate that Australian C. irritans isolates from estuarine (Moreton Bay) and coral reef (Heron Island) environments are distinct. The Heron Island isolate was genetically closer to morphologically dissimilar isolates from Israel (1.8% divergence) and the USA (2.3% divergence) than it was to the Moreton Bay isolates. Three isolates maintained in our laboratory since February 1994 differed in sequence from earlier laboratory isolates (2.9% to 3.5% divergence), even though all were similar morphologically and originated from the same source. During this time the sequence of the isolates from wild fish in Moreton Bay remained unchanged. These genetic differences indicate the existence of a founder effect in laboratory populations of C. irritans. The genetic variation found here, combined with known morphological and developmental differences, is used to characterise four strains of C. irritans.

  16. Copy number variation and mutation

    Science.gov (United States)

    Clark, Brian; Weidner, Jacob; Wabick, Kevin

    2009-11-01

    Until very recently, the standard model of DNA included two genes for each trait. This dated model has given way to a model that includes copies of some genes well in excess of the canonical two. Copy number variations in the human genome play critical roles in causing or aggravating a number of syndromes and diseases while providing increased resistance to others. We explore the role of mutation, crossover, inversion, and reproduction in determining copy number variations in a numerical simulation of a population. The numerical model consists of a population of individuals, where each individual is represented by a single strand of DNA with the same number of genes. Each gene is initially assigned to one of two traits. Fitness of the individual is determined by the two most fit genes for trait one, and trait two genetic material is treated as a reservoir of junk DNA. After a sufficient number of generations, during which the genetic distribution is allowed to reach a steady-state, the mean numberof genes per trait and the copy number variation are recorded. Here, we focus on the role of mutation and compare simulation results to theory.

  17. Longitudinal Variations in Jupiter's Winds

    Science.gov (United States)

    Simon-Miller, Amy A.; Gierasch, P. J.; Tierney, G.

    2010-01-01

    Long-term studies of Jupiter's zonal wind field revealed temporal variations on the order of 20 to 40 m/s at many latitudes, greater than the typical data uncertainties of 1 to 10 m/s. No definitive periodicities were evident, however, though some latitudinally-confined signals did appear at periods relevant to the Quasi- Quadrennial Oscillation (Simon-Miller & Gierasch, Icarus, in press). As the QQO appears, from vertical temperature profiles, to propagate downward, it is unclear why a signal is not more obvious, unless other processes dominate over possibly weaker forcing from the QQO. An additional complication is that zonal wind profiles represent an average over some particular set of longitudes for an image pair and most data sets do not offer global wind coverage. Lien avoiding known features, such as the large anticyclonic vortices especially prevalent in the south, there can be distinct variations in longitude. We present results on the full wind field from Voyager and Cassini data, showing apparent longitudinal variations of up to 60 m/s or more. These are particularly obvious near disruptions such as the South Equatorial Disturbance, even when the feature itself is not clearly visible. These two dates represent very different states of the planet for comparison: Voyagers 1 & 2 flew by Jupiter shortly after a global upheaval, while many regions were in a disturbed state, while the Cassini view is typical of a more quiescent period present during much of the 1990s and early 2000s.

  18. Evaluation of Mungbean Mutant Lines to Drought Stress and Their Genetic Relationships Using SSR Markers

    Directory of Open Access Journals (Sweden)

    Yuliasti

    2015-12-01

    Full Text Available Development of mungbean cultivarstolerant to drought stress through mutation breeding approach would enable us to anticipate the crop yield-reducing effects of climate changes. The objective of this research was to evaluate the yield performance of mungbean mutant lines that showed tolerance to drought stress, and to analyze their genetic diversity and relationship among mutant lines using SSR markers. The study was conducted during the dry season of 2012 in the Muneng experimental farm, Probolinggo, East Java. The experiment was laid out in a randomized block design with four replications. Five mutant lines and two parental lines as control were tested for evaluation of yield and drought tolerance under twoenvironments of two irrigation systems as treatment. The two environmental conditions consisted of optimal irrigation (at least three times: at planting, flowering and during pod filling and suboptimal irrigation (two times at planting and flowering. To evaluate genetic variation among selected mutant lines and their discrimination from parental lines in molecular level, a cluster analysis was performed using Unweighted Pair Group Method with Arithmetic Mean (UPGMA in the NTSYS software. The results showed that three mutant lines, including PsJ30, PsJ31, PsJ32 produced the highest grain yields of 1.17, 1.01, and 1.04 ton/ha, respectively, compared to the other mutant lines and the parents Gelatik (0.85 ton/ha and Perkutut (0.87 ton/ha as control check. Of those mutant lines, PSJ31 was the most tolerant to drought with sensitivity index value of 0.47. The PSJ31 has now been officially released as a new variety ( 2013, named as Muri which was identified to have high yield and tolerant to drought. Based on 23 SSR markers used for clustering analysis of those 3 selected mutant lines,9SSR markers (MBSS R033; satt137; MBSSR008; MBSSR203; MBSSR013; MBSSR021; MBSSR016; MBSSR136; and DMBSSR013 were successfully identified the three mungbean mutant

  19. 14 CFR 121.440 - Line checks.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Line checks. 121.440 Section 121.440..., FLAG, AND SUPPLEMENTAL OPERATIONS Crewmember Qualifications § 121.440 Line checks. (a) No certificate... preceding 12 calendar months, that person has passed a line check in which he satisfactorily performs the...

  20. 30 CFR 56.4501 - Fuel lines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuel lines. 56.4501 Section 56.4501 Mineral... Installation/construction/maintenance § 56.4501 Fuel lines. Fuel lines shall be equipped with valves capable of stopping the flow of fuel at the source and shall be located and maintained to minimize fire hazards. This...