WorldWideScience

Sample records for variables special emphasis

  1. Environmental studies on radioecological sensitivity and variability with special emphasis on the fallout nuclides 90Sr and 137Cs. Pt. 1

    International Nuclear Information System (INIS)

    Aarkrog, A.

    1979-06-01

    Radioecological sensitivity and variability are quantities that are used to characterize the radioecological properties of environmental samples. The radioecological sensitivity is the infinite time-integrated radionuclide concentration in the environmental sample considered arising from a deposition of 1 mCi KM -2 of the radionuclide in question. This quantity makes it possible to compare various environments as to their vulnerability to a given radioactive contamination. The variability of the concentrations of a radionuclide in an environmental sample, with respect to a given parameter, is defined as the partial coefficient of variation due to this parameter. The variability with time is a useful way to assess the route of contamination of the sample and the local variability is a measure of environmental inhomogenity with respect to radioactive contamination. Radioecology sensitivity and variability were applied to the 90 Sr and 137 Cs data obtained from the environmental studies on the human foodchain carried out during the last two decades in Denmark, the Faroe Islands, and Greenland. The per caput effective dose-equivalent commitments from radioactive debris from nuclear weapons testing was estimated to be 1.6 mSv in Denmark, 4.2 mSv in the Faroe Islands, and 1.6 mSv in Greenland. (author)

  2. Molecular Methods for Typing of Streptococcus agalactiae with Special Emphasis on the Development and Validation of a Multi-Locus Variable Number of Tandem Repeats Assay (MLVA)

    OpenAIRE

    Radtke, Andreas

    2012-01-01

    Molekylære metoder for typing av Streptococcus agalactiae med særlig vektlegging av utvikling og validering av et multi-locus variable number of tandem repeats assay (MLVA) Sammendraget: Streptococcus agalactiae eller gruppe B streptokokker (GBS) forårsaker livsfarlige infeksjoner hos nyfødte, gravide eller voksne med kroniske sykdommer. Den forårsaker også jurbetennelse i storfe. Typing av GBS gir innblikk i bakteriens epidemiologi og dens fylogenetiske slektskap. Ulike deler av bakterie...

  3. Micronutrient problems in Brazilian soils with special emphasis on zinc

    International Nuclear Information System (INIS)

    Stewart, J.W.B.; Neptune, A.M.L.; Sao Paulo Univ., Piracicaba

    1975-01-01

    Brazil, with approximately 50% of the total land area in South America, has areas in which different micronutrient deficiencies (zinc, boron, copper, iron, manganese and molybdenum) have been noted in specific crops. This paper reviews the published research on such deficiencies and puts special emphasis on zinc which appears to be the most widespread deficiency. The need for an integrated approach to determining the extent of micronutrient deficiencies is discussed. (author)

  4. 77 FR 39497 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-07-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Special Interest Projects (SIPs): Nutrition and Obesity Policy Research and...

  5. DIGITAL LIBRARIES IN INDONESIA WITH SPECIAL EMPHASIS TO ACADEMIC LIBRARIES

    OpenAIRE

    Sulistiyo Basuki

    2012-01-01

    There are many definitions about digital library, however, this paper used the definition taken from Digital Library Federation which stated that digital library as organizations that provide the resources, including the specialized staff, to select, structure, offer intellectual access to interpret, distribute, preserve the integrity of, and ensure the persistence over time of collections of digital works so that they are readily and economically available for use by defined community or set...

  6. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review

    Science.gov (United States)

    2013-04-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review The meeting announced below concerns Monitoring Cause-Specific School Absenteeism for Estimating Community Wide...

  7. 77 FR 25180 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Conducting Research on Moderate Acute Malnutrition in Humanitarian Emergencies...

  8. 76 FR 18766 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-04-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Epidemiologic Research and Surveillance in Epilepsy, Funding Opportunity...

  9. 78 FR 13677 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Science.gov (United States)

    2013-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding Opportunity Announcement, Initial Review The meeting announced below concerns Indoor Environment of Low- Income Renovated...

  10. 77 FR 20822 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Detecting Emerging Vector- Borne Zoonotic Pathogens in Indonesia, Funding...

  11. 77 FR 19018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-03-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Conducting Public Health Research in South Africa, Funding Opportunity Announcement...

  12. 78 FR 15015 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review

    Science.gov (United States)

    2013-03-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review The meeting announced below concerns Epidemiology, Prevention and Treatment of Influenza and other Respiratory...

  13. 77 FR 14806 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-03-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Epidemiology, Prevention and Treatment of Influenza and Other Respiratory...

  14. 78 FR 78966 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-12-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Epidemiology, Prevention, and Treatment of Influenza and Other Respiratory...

  15. 77 FR 4048 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Evaluation of Dengue Epidemiology, Outcomes, and Prevention in Sentinel...

  16. 77 FR 4047 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Epidemiology, Prevention and Treatment of Influenza and Other Respiratory...

  17. 78 FR 62636 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Cooperative Agreement on Occupational Health with the World Health Organization...

  18. 78 FR 13677 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review

    Science.gov (United States)

    2013-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review The meeting announced below concerns Monitoring Cause-Specific School Absenteeism for Estimating Community Wide...

  19. 76 FR 29756 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-05-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Centers for Agricultural Disease and Injury Research, Education, and Prevention...

  20. 78 FR 60878 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Health Promotion and Disease Prevention Research Centers, Funding Opportunity...

  1. 78 FR 17412 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Science.gov (United States)

    2013-03-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding Opportunity Announcement, Initial Review The meeting announced below concerns Indoor Environment of Low- Income Renovated...

  2. 77 FR 12844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-03-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Detecting Emerging Vector- Borne Zoonotic Pathogens in Indonesia, Funding...

  3. 75 FR 76987 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Science.gov (United States)

    2010-12-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epidemiologic and Ecologic...), the Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and...

  4. 77 FR 39498 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-07-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Special Interest Project (SIP): Assessing the Pregnancy Prevention Needs of HIV...

  5. 76 FR 32213 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Initial Review

    Science.gov (United States)

    2011-06-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Initial Review The meeting announced below concerns Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color...

  6. 76 FR 52330 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-08-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, initial review. In...

  7. 77 FR 28392 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-05-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Alcohol-related Motor Vehicle Injury Research, FOA CE12-006, initial review. In...

  8. 78 FR 19269 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-03-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of Cancellation: This document corrects a notice that was published in the Federal Register on March 21, 2013 (78...

  9. 78 FR 20319 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review.

    Science.gov (United States)

    2013-04-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review. The meeting... aforementioned SEP: Time and Date: 9:00 a.m.-6:00 p.m., May 15-16, 2013 (Closed). Place: Georgian Terrace, 659...

  10. 78 FR 60879 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns National Center for Construction Safety and Health Research and Translation (U60...

  11. 76 FR 13413 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Meeting

    Science.gov (United States)

    2011-03-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Meeting Studies at the Animal-Human Interface of Influenza and Other Zoonotic Diseases in Vietnam, Funding Opportunity Announcement...

  12. 76 FR 78263 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-12-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational Safety and Health Training Project Grants, Program Announcement PAR 10...

  13. 77 FR 291 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-01-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns National HIV Behavioral Surveillance For Young Men Who Have Sex With Men, Funding...

  14. 78 FR 78964 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-12-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns The Cooperative Re-Engagement Controlled Trial (CoRECT), Funding Opportunity...

  15. 78 FR 66938 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-11-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of..., Number 181, Page 57391). This SEP, scheduled to convene on November 12-15, 2013, is canceled. Notice will...

  16. 78 FR 60877 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational Safety and Health Training Project Grants (T03), PAR-10-288, initial...

  17. 77 FR 30015 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-05-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Characterizing the Short and Long Term Consequences of Traumatic Brain Injury (TBI...

  18. 78 FR 24751 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-04-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting... Control and Prevention (CDC) announces the aforementioned SEP: Time and Date: 12:00 p.m.-3:30 p.m., June...

  19. 77 FR 31018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-05-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, and Centers of Excellence...

  20. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-04-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of Cancellation: A notice was published in the Federal Register on February 12, 2013, Volume 78, Number 29, page...

  1. 76 FR 18555 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-04-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Virologic Evaluation of the Modes of Influenza Virus Transmission among Humans...

  2. 76 FR 33304 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-06-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Strategies to Improve Vaccination Coverage of Children in Child Care Centers (CCCs...

  3. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Meeting

    Science.gov (United States)

    2011-05-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Meeting Studies at the Animal-Human Interface of Influenza and Other Zoonotic Diseases in Vietnam, Funding Opportunity Announcement...

  4. 78 FR 35035 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review

    Science.gov (United States)

    2013-06-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review The meeting announced below concerns Centers for Disease Control and Prevention Public Health Preparedness and Response...

  5. 78 FR 25743 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-05-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, initial review. In...

  6. 77 FR 7164 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-02-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, initial review. In...

  7. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-11-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of... Volume 78, Number 191, Page 60877). This SEP, scheduled to convene on November 6, 2013, is canceled...

  8. 77 FR 22326 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Extension of the World Trade Center Health Registry (U50) Request for Applications...

  9. 78 FR 17412 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-03-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Strengthening the Monitoring and Evaluation of Programs for the Elimination and...

  10. 77 FR 28393 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-05-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Research to Prevent Prescription Drug Overdoses, FOA CE12-007, initial review. In...

  11. 78 FR 36785 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-06-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Centers for Disease Control and Prevention Public Health Preparedness and Response...

  12. 77 FR 25181 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Research Technical Assistance To The Ministry Of Public Health Of Haiti To Support...

  13. 78 FR 1212 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-01-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Natural History and Prevention of Viral Hepatitis Among Alaska Natives, Funding...

  14. 78 FR 60875 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational Safety and Health Training Project Grants (T03), PAR-10-288, initial...

  15. 76 FR 24031 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-04-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Strategies to Improve Vaccination Coverage of Children in Child Care Centers (CCCs...

  16. 76 FR 28790 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, initial review. In...

  17. 76 FR 39879 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-07-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who...

  18. 78 FR 23768 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-04-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting... Centers for Disease Control and Prevention (CDC) announces the aforementioned SEP: Time and Date: 1:00 p.m...

  19. 77 FR 27460 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Conducting Public Health Research in China RFA GH-12-005, and Conducting Public...

  20. 76 FR 59133 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-09-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who...

  1. 76 FR 67458 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-11-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Emerging Infections Programs, Funding Opportunity Announcement (FOA) CK12-1202...

  2. 77 FR 48986 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-08-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict Review, Program Announcement (PA) 07-318, initial review. In...

  3. 78 FR 9926 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-02-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Medicaid Expansion and Reproductive Health Care for Women, FOA DP 13-002, initial...

  4. 77 FR 61756 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-10-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational Safety and Health Training Project Grant, PAR 10-288, initial review...

  5. 78 FR 17410 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial review

    Science.gov (United States)

    2013-03-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial review The meeting announced below concerns Epi-Centers for the Prevention of Healthcare-Associated Infections, Antimicrobial...

  6. 78 FR 17411 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-03-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Monitoring and Evaluation of Malaria Control and Elimination Activities, FOA GH13...

  7. 78 FR 37542 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-06-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns NIOSH Cooperative Agreement Research to Aid Recovery from Hurricane Sandy, Request...

  8. 76 FR 45575 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-07-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who...

  9. 78 FR 56236 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-09-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns NIOSH Member Conflict Review, PA 07-318, initial review. In accordance with Section...

  10. 78 FR 28221 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-05-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting... aforementioned SEP: Time and Date: 12:30 p.m.-5:00 p.m. EDT, July 24, 2013 (Closed). Place: Teleconference...

  11. 77 FR 36544 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-06-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Coordinating Center for Research and Training to Promote the Health of People with...

  12. 77 FR 5026 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-02-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting... SEP: Occupational Safety and Health Education and Research Centers, PAR 10-217. Contact Person For...

  13. 78 FR 732 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-01-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Identification, Surveillance, and Control of Vector-Borne and Zoonotic Infectious...

  14. 76 FR 33305 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-06-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Program to Support New Implementation of State or Territorial Public Health...

  15. 78 FR 57391 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-09-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting... aforementioned SEP: Times and Dates: 8:00 a.m.-8:00 p.m., November 12-15, 2013 (Closed). Place: Teleconference...

  16. 76 FR 3909 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Science.gov (United States)

    2011-01-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family History and Diamond..., discussion, and evaluation of ``Family History and Diamond Blackfan Anemia, DD11-010, initial review...

  17. 75 FR 41872 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Science.gov (United States)

    2010-07-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance, Natural History... evaluation of ``Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset...

  18. 75 FR 13560 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Science.gov (United States)

    2010-03-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance, Natural History... evaluation of ``Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus With Onset...

  19. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Science.gov (United States)

    2011-03-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010, Initial Review Correction: This notice was published in the Federal Register on...

  20. 75 FR 29561 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Science.gov (United States)

    2010-05-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence, RFA DP 10-001...

  1. 76 FR 4911 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Science.gov (United States)

    2011-01-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational Safety and Health...)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and...

  2. 75 FR 4406 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Science.gov (United States)

    2010-01-27

    ... recommendations to the Disease, Disability, and Injury Prevention and Control SEP: Occupational Safety and Health... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational Safety and Health Training...

  3. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Science.gov (United States)

    2010-12-17

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the..., discussion, and evaluation of ``Maternal Vitamin D Status and Preterm Birth, DP11-002, initial review...

  4. 76 FR 10908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Science.gov (United States)

    2011-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and... 17, 2011. Elaine L. Baker, Director, Management Analysis and Services Office, Centers for Disease...

  5. 76 FR 20355 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Science.gov (United States)

    2011-04-12

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding Opportunity Announcement... Research Network (MD STARnet); Feasibility of Expansion to Other Muscular Dystrophies (FOA) DD11-006... Network (MD STARnet); Feasibility of Expansion to Other Muscular Dystrophies (FOA) DD11-006, initial...

  6. 76 FR 9018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging...

    Science.gov (United States)

    2011-02-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging Infections Sentinel... with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease...

  7. Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals.

    Science.gov (United States)

    Healy, Anne Marie; Worku, Zelalem Ayenew; Kumar, Dinesh; Madi, Atif M

    2017-08-01

    Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, affecting the internal energy and enthalpy, and the degree of disorder, affecting the entropy. Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility, dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development in the context of optimization of bioavailability, filing intellectual property rights and developing suitable manufacturing methods. In this review, the fundamental characteristics and trends observed for pharmaceutical hydrates, solvates and amorphous forms are presented, with special emphasis, due to their relative abundance, on pharmaceutical hydrates with single and two-component (i.e. cocrystal) host molecules. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Comparative assessment of metallurgical recovery of metals from electronic waste with special emphasis on bioleaching.

    Science.gov (United States)

    Priya, Anshu; Hait, Subrata

    2017-03-01

    Waste electrical and electronic equipment (WEEE) or electronic waste (e-waste) is one of the fastest growing waste streams in the urban environment worldwide. The core component of printed circuit board (PCB) in e-waste contains a complex array of metals in rich quantity, some of which are toxic to the environment and all of which are valuable resources. Therefore, the recycling of e-waste is an important aspect not only from the point of waste treatment but also from the recovery of metals for economic growth. Conventional approaches for recovery of metals from e-waste, viz. pyrometallurgical and hydrometallurgical techniques, are rapid and efficient, but cause secondary pollution and economically unviable. Limitations of the conventional techniques have led to a shift towards biometallurgical technique involving microbiological leaching of metals from e-waste in eco-friendly manner. However, optimization of certain biotic and abiotic factors such as microbial species, pH, temperature, nutrients, and aeration rate affect the bioleaching process and can lead to profitable recovery of metals from e-waste. The present review provides a comprehensive assessment on the metallurgical techniques for recovery of metals from e-waste with special emphasis on bioleaching process and the associated factors.

  9. Power production from biomass II with special emphasis on gasification and pyrolysis R and DD

    Energy Technology Data Exchange (ETDEWEB)

    Sipilae, K; Korhonen, M [eds.; VTT Energy, Espoo (Finland). Energy Production Technologies

    1997-12-31

    The Seminar on Power Production from Biomass II with special emphasis on gasification and pyrolysis R and DD, was organized by VTT Energy on 27 - 28 March 1995 in Espoo, Finland. All seminar speakers were invited in order to give a high-level overview of the achievements of biomass combustion, gasification and flash pyrolysis technologies. The sessions included presentations by all key industrial entrepreneurs in the field. The poster session was open to all groups interested. Globally bioenergy covers about 3 % of the primary energy consumption. Locally it has a significant role in many countries like in Finland, where bioenergy covers almost 15 % and peat 5 % of primary energy consumption. Today`s cost-effective heat and power production is based on industrial wood residues and spent cooking liquors in relatively large industrial units or municipal heating and power stations. Agricultural residues like straw and especially energy crops are becoming more interesting in co-utilization with other biomasses or fossil fuels. The seminar successfully displayed the status of present technologies as well as development targets for new gasification and flash pyrolysis technologies in the coming years. The many industrial participants showed that there are growing business possibilities in many countries all over the world. The proceedings include the most oral presentations given at the Seminar and also abstracts of poster presentations. (orig.)

  10. Power production from biomass II with special emphasis on gasification and pyrolysis R and DD

    Energy Technology Data Exchange (ETDEWEB)

    Sipilae, K.; Korhonen, M. [eds.] [VTT Energy, Espoo (Finland). Energy Production Technologies

    1996-12-31

    The Seminar on Power Production from Biomass II with special emphasis on gasification and pyrolysis R and DD, was organized by VTT Energy on 27 - 28 March 1995 in Espoo, Finland. All seminar speakers were invited in order to give a high-level overview of the achievements of biomass combustion, gasification and flash pyrolysis technologies. The sessions included presentations by all key industrial entrepreneurs in the field. The poster session was open to all groups interested. Globally bioenergy covers about 3 % of the primary energy consumption. Locally it has a significant role in many countries like in Finland, where bioenergy covers almost 15 % and peat 5 % of primary energy consumption. Today`s cost-effective heat and power production is based on industrial wood residues and spent cooking liquors in relatively large industrial units or municipal heating and power stations. Agricultural residues like straw and especially energy crops are becoming more interesting in co-utilization with other biomasses or fossil fuels. The seminar successfully displayed the status of present technologies as well as development targets for new gasification and flash pyrolysis technologies in the coming years. The many industrial participants showed that there are growing business possibilities in many countries all over the world. The proceedings include the most oral presentations given at the Seminar and also abstracts of poster presentations. (orig.)

  11. Analysis of the Plasma Properties Affected by Magnetic Confinement with Special Emphasis on Helicon Discharges

    International Nuclear Information System (INIS)

    Cheng Yuguo; Cheng Mousen; Wang Moge; Yang Xiong; Li Xiaokang

    2014-01-01

    A one-dimensional radial non-uniform fluid model is employed to study plasma behaviors with special emphasis laid on helicon discharges. The plasma density n e , electron temperature T e , electron azimuthal and radial drift velocities are investigated in terms of the plasma radius r p , magnetic field intensity B 0 and gas pressure p 0 , by assuming radial ambipolar diffusion and negligible ion cyclotron movement. The results show that the magnetic confinement plays an important role in the discharge equilibrium, especially at low pressure, which significantly reduces T e compared with the case of a negligible magnetic field effect, and higher B 0 leads to a greater average plasma density. T e shows little variations in the plasma density range of 10 11 cm −3 –10 13 cm −3 for p 0 < 3.0 mTorr. Comparison of the simulation results with experiments suggests that the model can make reasonable predictions of T e in low pressure helicon discharges. (low temperature plasma)

  12. 75 FR 13560 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): RFA DD 10...

    Science.gov (United States)

    2010-03-22

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): RFA DD 10-002 Public Health Research on Spina Bifida, RFA DD 10-003 Public Health Research on Children and Adults Living With Spina Bifida, RFA DD 10-004 Developing a Prospective Assessment of the Development, Health, and Condition...

  13. Vanadate and phosphotransferases with special emphasis on ouabain/Na, K-ATPase interaction

    International Nuclear Information System (INIS)

    Hansen, O.

    1983-01-01

    A short introduction to the chemistry and possible physiological or toxicological role of vanadium is given. The +5 oxidation state, vanadate, is a very efficient inhibitor of several phosphotransferases and for that reason a prosperous tool in the study of such enzymes. Special emphasis is placed on studies with vanadate on the sodium pump. Vanadate appears to supplement ouabain as high affinity inhibitor of Na,K-ATPase. They are also complementary to one another since vanadate binds to the cytoplasmic aspect and ouabain to the extracellular side of the cell membrane, and moreover, they potentiate the binding of one another. The hypothesis that vanadate may act as a transition state analogue of phosphate seems supported by the observation that vanadate, like phosphate, is able to induce ouabain binding to Na,K-ATPase. The vanadate affinity is much higher than that of phosphate, however, and vanadate remains bound in a rather stable enzyme-vanadate-ouabain complex. Fluorescene studies indicate that different subspecies of an E 2 -conformation of the enzyme is obtained with vanadate and with ouabain. In molecular studies on Na,K-ATPase, e.g. in studies on the protein folding through the plasma-membrane, one can imagine that the simultaneous binding of an extracellular marker, ouabain, and of the intracellular marker, vanadate, may be most helpful tools. A proposed physiological regulatory role of vanadium on the pump activity seems less likely considering the simultaneous acceleration of K + -uptake which is probably due to adenylate cyclase activation. Vanadate seems more likely to have a pharmacological role as a cofactor for digitals binding to Na,K-ATPase. Finally, the vasoconstriction evoked by vanadate could indicate a pathophysiological role of the ion and vanadate could then become useful tool in experimental hypertension and uremia. (author)

  14. ROAD TRANSPORT OF DANGEROUS SUBSTANCE WITH SPECIAL EMPHASIS ON LIQUID FUELS

    Directory of Open Access Journals (Sweden)

    Adam Salomon

    2015-09-01

    Full Text Available The article presents the characteristics of the transport of dangerous goods by road transport. It contains issues relating to the legal aspects, the risk to traffic and transport requirements for participants in force in the European Union and Poland. Particular emphasis has been placed on issues related to the carriage of liquid fuels.

  15. The selection criteria for Slovenian bibliography: with special emphasis on the articles

    Directory of Open Access Journals (Sweden)

    Marjeta Šušteričič

    2010-01-01

    Full Text Available Selection principles are an important stage in the creation of a national bibliography.The article outlines the selection of the national output to be included in Slovenian bibliography. It also presents theoretical basis for selection in general, with the emphasis on international guidelines and on the development of national principles and professional outlines. Statistical data and examples give more detailed analysis of selection criteria of articles regarding different types of serial publications. Results of the study show that selection criteria for Slovenian bibliography are to be constantly verified due to the dynamics of the national publishing industry. Nevertheless, the main features of selection criteria remain unchanged: lasting value of subject matter with the emphasis on scientific research and expert knowledge.

  16. Revisiting the evolution of ecological specialization, with emphasis on insect-plant interactions.

    Science.gov (United States)

    Forister, M L; Dyer, L A; Singer, M S; Stireman, J O; Lill, J T

    2012-05-01

    Ecological specialization is a fundamental and well-studied concept, yet its great reach and complexity limit current understanding in important ways. More than 20 years after the publication of D. J. Futuyma and G. Moreno's oft-cited, major review of the topic, we synthesize new developments in the evolution of ecological specialization. Using insect-plant interactions as a model, we focus on important developments in four critical areas: genetic architecture, behavior, interaction complexity, and macroevolution. We find that theory based on simple genetic trade-offs in host use is being replaced by more subtle and complex pictures of genetic architecture, and multitrophic interactions have risen as a necessary framework for understanding specialization. A wealth of phylogenetic data has made possible a more detailed consideration of the macroevolutionary dimension of specialization, revealing (among other things) bidirectionality in transitions between generalist and specialist lineages. Technological advances, including genomic sequencing and analytical techniques at the community level, raise the possibility that the next decade will see research on specialization spanning multiple levels of biological organization in non-model organisms, from genes to populations to networks of interactions in natural communities. Finally, we offer a set of research questions that we find to be particularly pressing and fruitful for future research on ecological specialization.

  17. A THREE YEAR RETROSPECTIVE STUDY OF OVARIAN NEOPLASMS WITH SPECIAL EMPHASIS ON SURFACE EPITHELIAL TUMOURS

    Directory of Open Access Journals (Sweden)

    Krishna Bharathi Yarlagadda

    2016-07-01

    Full Text Available BACKGROUND Ovarian tumours being second most common gynaecological cancer in India account for 30% of all cancers of female genital tract. Study conducted to determine relative frequencies of various histological types based on WHO classification and their age distribution with particular emphasis on surface epithelial tumours. This study is undertaken to find out the frequency of incidence of different histopathological subtypes with particular emphasis on surface epithelial tumours and age distribution of ovarian tumours in our institute located in coastal Andhra Pradesh. METHODS This is a retrospective study of 100 cases of ovarian neoplasms collected during a period of 3 years from June 2013 to May 2016 from the Department of Pathology, Katuri Medical College and Hospital, Chinakondrupadu, Guntur, A. P, India. The patients attending our hospital are mostly from rural areas around. Paraffin blocks of all 100 ovarian neoplasms retrieved. Complete clinical and radiological findings analysed from our records. RESULTS The tumours are grouped according to the nature of tumour whether benign or borderline or malignant according to cell of origin, histological subtyping, and age group. Surface epithelial tumours are the most common. Benign tumours outnumber the malignant tumours. Benign ovarian tumours showed a peak in 21-40 Yrs. age group and malignant in the age group of 41- 60 Yrs. Results of our study compared with other studies. CONCLUSION Because of the geographic location, poverty, and illiteracy, patients seek medical advice late. So, awareness among public by health education, passive surveillance, and community screening facility will be helpful in early detection of ovarian neoplasms.

  18. Abortion trends from 1996 to 2011 in Estonia: special emphasis on repeat abortion

    Science.gov (United States)

    2014-01-01

    Background The study aimed to describe the overall and age-specific trends of induced abortions from 1996 to 2011 with an emphasis on socio-demographic characteristics and contraceptive use of women having had repeat abortions in Estonia. Methods Data were retrieved from the Estonian Medical Birth and Abortion Registry and Statistics Estonia. Total induced abortion numbers, rates, ratios and age-specific rates are presented for 1996–2011. The percentage change in the number of repeat abortions within selected socio-demographic subgroups, contraception use and distribution of induced abortions among Estonians and non-Estonians for the first, second, third, fourth and subsequent abortions were calculated for the periods 1996–2003 and 2004–2011. Results Observed trends over the 16-year study period indicated a considerable decline in induced abortions with a reduction in abortion rate of 57.1%, which was mainly attributed to younger cohorts. The percentage of women undergoing repeat abortions fell steadily from 63.8% during 1996–2003 to 58.0% during 2004–2011. The percentage of women undergoing repeat abortions significantly decreased over the 16 years within all selected socio-demographic subgroups except among women with low educational attainment and students. Within each time period, a greater percentage of non-Estonians than Estonians underwent repeat abortions and obtained third and subsequent abortions. Most women did not use any contraceptive method prior to their first or subsequent abortion. Conclusion A high percentage of women obtaining repeat abortions reflects a high historical abortion rate. If current trends continue, a rapid decline in repeat abortions may be predicted. To decrease the burden of sexual ill health, routine contraceptive counselling, as standard care in the abortion process, should be seriously addressed with an emphasis on those groups - non-Estonians, women with lower educational attainment, students and women with children

  19. Safety and reliability of pressure components with special emphasis on advanced methods of NDT. Vol. 1

    International Nuclear Information System (INIS)

    1986-01-01

    24 papers discuss various methods for nondestructive testing of materials, e.g. eddy current measurement, EMAG analyser, tomography, ultrasound, holographic interferometry, and optical sound field camera. Special consideration is given to mathematical programmes and tests allowing to determine fracture-mechanical parameters and to assess cracks in various components, system parts and individual specimens both in pressurized systems and NPP systems. Studies focus on weld seams and adjacent areas. (DG) [de

  20. Differential neurotoxic effects of silver nanoparticles: A review with special emphasis on potential biomarkers

    Directory of Open Access Journals (Sweden)

    M. Safari

    2016-04-01

    Full Text Available Silver Nanoparticles (AgNPs have gained considerable interests during the last decade due to their excellent antimicrobial activities. Despite their extensive use, the potential toxicity of these nanoparticles and possible mechanisms by which they may induce adverse reactions have not received sufficient attention and no specific biomarker exist to describe and quantify their toxic effects. Nanoparticles, depending on their physicochemical characteristics and compositions, can interact with vital organs such as the brain and induce toxic effects. A specific concern is that any contact with AgNPs independent of the route of administration is thought to result in significant systemic uptake, internal exposure of sensitive organs, especially in the central nervous system (CNS and different toxic responses. There are considerable evidences that AgNPs can disrupt the Blood-Brain Barrier (BBB and induce subsequent brain edema formation. Therefore, it is essential to understand the differential effects of AgNPs on brain cell with especial emphasis on the possible mechanisms of action. Recently, biomarkers are increasingly used as surrogate indicators of toxic responses in biological monitoring due to the inaccessibility of target organs. Moreover, as the most nanoscale contaminants occur at low concentrations, physiological biomarkers may be better indicators of potential impact of nanomaterials than traditional toxicity testing. This review aims to investigate the effects of AgNPs on CNS targets of toxicity and clarify the role of existing biomarkers especially the role of dopamine levels as a potential biomarker of Ag-NPs neurotoxicity.

  1. Forms of international movement of capital with special emphasis on the PPP and concessions

    Directory of Open Access Journals (Sweden)

    Šovran Sanja

    2016-01-01

    Full Text Available The state has always cooperated with the private sector in order to implement various activities in the best interest of public. The first models of public-private partnerships (PPP appeared at the time of the Roman Empire in the context of public works in construction of public baths, markets and ports. Contemporary international movement of capital is a phenomenon that has existed for over a century. When discussing the PPP in modern day terms, the expansion of private involvement in the public sector starts in the 1970s and the 1980s of the previous century, in public infrastructure projects and in most developed economies. The primary purpose of these arrangements is to reduce expenditures in state budgets, but also to achieve faster and better execution of work, reduce risk and efficiently manage the projects. This paper will briefly present the evolution of PPPs and concessions, with an emphasis on understanding money and capital throughout the evolution of PPP, contemporary forms of movement of capital, as well as equity in terms of globalization. The subject of this paper are also examples of the important PPPs and concessions from the construction of the Suez Canal until today.

  2. Microbial growth in domestic hot water systems with special emphasis on connections to district heating networks

    Energy Technology Data Exchange (ETDEWEB)

    Frederiksen, S [Lund Institute of Technology, Dept. of Heat and Power Engineering, Lund (SE); Krongaard Kristensen, K [Regional Food and Hygiene Authority, Koebenhavns Amt Vest, Glostrup (DK)

    1991-01-01

    It is by now well-estalished that domestic hot water systems often harbour Legionella bacteria. Measurements into a number of Danish systems have revealed many other bacteria, among them the thermophilic species Thermus, which is predominantly found on heating coils, where local temperatures are higher. This bacterium not only hampers heat transfer due to fouling, but may also be pathogenic, due to release of endotoxins. Its presence may explain a wide spectrum of symptoms experienced by people after hot baths, such as rashes and itching. The paper summarizes these findings, and on this basis engineering and microbiological considerations are presented in an effort to find ways of future control strategies that go beyond Legionella prevention. Special attention is given to district heating connections, in which low supply and return temperatures are generally wanted in the primary circuit. (author) 16 refs.

  3. The certification and decertification process of elections, with special emphasis in the Republic of Kosovo

    Directory of Open Access Journals (Sweden)

    Sadik Haxhiu

    2018-03-01

    Full Text Available The right of all adult citizens to participate in the issues of their country’s governance is one of the cornerstones of democracy. Election participation is defined by internal legal acts such as constitution, laws, electoral codes, and through international legal acts. This right has been limited throughout history, by completely banning certain categories of citizens to participate in elections or by placing voters’ censorship such as the rich, poor, educated, etc. Apart from the active and passive right to participate in the elections, the constitution and the electoral laws have also determined the right of exclusion from the elections. In the contemporary world, with internal norms and international law, special criteria are set for the certification and decertification of voters in the elections. The purpose of this paper is to assess the colliding norms that exist in Kosovo’s legislation regarding the participation of citizens in the elections, especially the colliding norms between the constitution and the electoral laws in the certification-de-certification provisions of the elections. With these shortcomings and ambiguities, international standards for democratic elections have been violated.

  4. 1977 guidebook to California taxes with special emphasis on relationship to Federal taxes

    Energy Technology Data Exchange (ETDEWEB)

    Bock, R.S.

    1977-01-01

    This book is designed to be a quick reference work on California State taxes. With this in mind, the amount of detail is kept to a minimum by assuming that the reader has some knowledge of Federal taxes that are generally similar to the major California taxes (or that he has access to the wealth of information about Federal taxes that is readily available). The book explains the four major California taxes (personal income tax, tax on corporate income, inheritance tax, and gift tax), whenever possible, in terms of the comparable Federal taxes. Differences between the two laws are pointed out, and cross-references make it possible to trace from a given provision in one law to a comparable provision in the other. Special attention is given to subjects peculiar to the California law. In addition to the major State taxes, the book provides general information about other taxes levied by the State. Property taxes are also discussed briefly, because of their statewide impact, although they are imposed by local governmental units.

  5. Absorbed doses from intraoral radiography with special emphasis on collimator dimensions

    International Nuclear Information System (INIS)

    Stenstroem, B.; Henrikson, C.O.; Holm, B.; Richter, S.; Huddinge Univ. Hospital, Huddinge

    1986-01-01

    Thermoluminescence dosimeters were used in a phantom head and on patients to measure the absorbed dose to organs of special interest from full surveys with intraoral films (20 exposures) and single bitewing exposures. Two x-ray machines were used, operating at 65 kVp. The apertures of the circular tube collimators had diameters of 55 mm and 48 mm. Rectangular (35 mm x44 mm) tube collimators were also used. The distance from the x-ray focus to the open end of the collimators (FSD) was 0.20 and 0.35 m. Exposure values for Kodak Ultra-Speed film (speed group D) were used. The maximum skin dose measured from the full surveys decreased by 25 per cent on changing from the circular to the rectangular apertures. Using 0.35 m FSD and rectangular collimator the maximum skin dose was 13 mGy. The absorbed doses to the salivary glands and the thyroid gland were significantly reduced on changing from circular to rectangular apertures. The doses in the central part of the parotid and the thyroid glands were then 0.5 and 0.12 mGy, respectively, from a full survey with 20 intraoral films. With a leaded shield the thyroid dose was reduced to 0.05 mGy. All dose values could be further reduced by 40 per cent by using Kodak Ektaspeed film (speed group E)

  6. Histological study of human sublingual gland with special emphasis on intercalated and striated ducts

    International Nuclear Information System (INIS)

    Rana, R.; Minhas, L.A.; Mubarik, A.

    2012-01-01

    Objective: To study the histomorphological characteristics of human sublingual gland, specially of intercalated and striated ducts. Study design: Descriptive study Place and duration of study: Army Medical College from Jan 2002 to Dec 2002 Materials and methods: Fifteen sublingual glands (right and left) from postmortem cases were obtained from District Headquarter Hospital Rawalpindi, within twelve hours of death. Five micrometer thick sections were made and stained with Haematoxylin and Eosin (H and E). Morphology of intercalated and striated ducts was studied and their number was counted. Results: The mean number of intercalated ducts in the right gland 'a'and 'b' parts, and in the left gland 'a' and 'b' parts was 1.45+-0.14, 1.39+-.009, 1.31+-0.11 and 1.18+-0.10 respectively. The mean diameter of intercalated ducts in the same parts was 19.76+-0.44 micro m, 20.6+-0.53 micro m, 20.34+-0.49 micro m and 19.84+-0.98 micro m respectively. The mean number of striated ducts in the right gland ''a'' and ''b'' parts, and in the left gland ''a'' and ''b'' parts was 0.55+-.008, 0.57+-.008, 0.80+-0.14 and 0.80+-0.14 while mean diameter of striated ducts in the right gland ''a'' and ''b'' parts, and in the left gland ''a'' and ''b'' parts was 49.90+-4.70 micro m, 53.23+-2.50 micro m, 61.68+-3.93 micro m and 57.73+-2.85 micro m respectively. Conclusion: The difference between the mean number and diameter of the ducts of right and left glands was statistically insignificant. (author)

  7. Clinical Characteristics of Connective Tissue Nevi in Tuberous Sclerosis Complex With Special Emphasis on Shagreen Patches.

    Science.gov (United States)

    Bongiorno, Michelle A; Nathan, Neera; Oyerinde, Oyetewa; Wang, Ji-An; Lee, Chyi-Chia Richard; Brown, G Thomas; Moss, Joel; Darling, Thomas N

    2017-07-01

    Patients with tuberous sclerosis complex (TSC) frequently develop collagenous connective tissue nevi. The prototypical lesion is a large shagreen patch located on the lower back, but some patients only manifest small collagenomas or have lesions elsewhere on the body. The ability to recognize these variable presentations can be important for the diagnosis of TSC. To describe the clinical characteristics of connective tissue nevi on the trunk and extremities of patients with tuberous sclerosis complex. A retrospective analysis of patient medical records and skin photography was performed; 104 adult patients with TSC were enrolled in an observational cohort study that was enriched for those with pulmonary lymphangioleiomyomatosis, and was therefore composed mostly of women (99 women, 5 men). All patients included were examined at the National Institutes of Health (NIH) in Bethesda, Maryland, from 1998 to 2013. Connective tissue nevi were categorized per anatomic location and size. Lesions less than 1 cm in diameter were termed collagenomas. Shagreen patches were characterized as small (1 to connective tissue nevi in patients with TSC. Overall, 58 of 104 patients (median [range] age, 42 [19-70] years) with TSC (56%) had at least 1 connective tissue nevus on the trunk or thighs; of these, 28 of 58 patients (48%) had a solitary lesion, and 30 of 58 patients (52%) had 2 or more lesions. Overall, 120 lesions from 55 patients were classified by size; 46 lesions (38%) were collagenomas; 39 lesions (32%) were small shagreen patches; 21 lesions (18%), medium shagreen patches; and 14 lesions (12%), large shagreen patches. The distribution of lesions was 9% (n = 11), upper back; 29% (n = 35), middle back; 51% (n = 61), lower back; and 11% (n = 13), other locations. All 26 shagreen patches that were analyzed histopathologically had coarse collagen fibers and 24 of 26 stained with Miller elastic stain had decreased elastic fibers. On immunoblot analysis

  8. Teacher and Student Variables Affecting Special Education Evaluation and Referral

    Science.gov (United States)

    Woodson, Lorenzo Adrian

    2017-01-01

    Past research has revealed that African American/Black boys are referred for special education evaluation at disproportionately higher rates than boys of other racial/ethnic groups. This correlational study used survey methodology to examine whether student and teacher demographic variables predicted how likely a teacher would refer boy students…

  9. [The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

    Science.gov (United States)

    Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

    2016-09-01

    The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot

  10. The use of economic forecasts in Danish economic policy, with special emphasis on energy and the environment

    International Nuclear Information System (INIS)

    Nielsen, Lise

    1998-01-01

    This article discusses the use of economic forecasts in Danish economic policy, with special emphasis on energy and the environment. Two different approaches have been used to forecast energy consumption and its effects on environment in Denmark and other countries. These are the macro economic and the technical approaches. The technical approach is based on technical expertise related to energy production and energy consumption, and the article asks whether the forecasts produced by this approach are superior to macro economic forecasts of energy consumption. This question is interesting because the implications for policy resulting from the two approaches seem to be different. The analysis may have relevance to other areas outside the main economic field. (au) 22 refs

  11. Variable quasi-stellar sources with particular emphasis on objects of the BL Lac type

    International Nuclear Information System (INIS)

    Kinman, T.D.

    1975-01-01

    The optically variable quasars tend to have steep optical spectra and to show variable polarization; they tend to be associated with compact radio sources which have flat radio spectra at GHz frequencies. Objects are known which have continuous spectra (like BL Lac and OJ 287), but whose other properties closely parallel those of the variable quasars and N galaxies; in fact no sharp distinction can be drawn between them. The variation in the visibility of emission lines in quasars and N galaxies could be due to variations in the strength and spectral index of the radiation from the non-thermal source and from the differences in the amount and disposition of the material around it; it does not seem likely that a combination of these factors accounts for the observed range in emission line strength. The systematic difference in optical spectral index between continuous-spectrum objects (and OVV variables) on the one hand and those with emission lines on the other will produce a difference in K term between them, which may be expected to affect their distributions with respect to apparent magnitude. (Auth.)

  12. Reformulated and alternative fuels: modeled impacts on regional air quality with special emphasis on surface ozone concentration.

    Science.gov (United States)

    Schell, Benedikt; Ackermann, Ingmar J; Hass, Heinz

    2002-07-15

    The comprehensive European Air Pollution and Dispersion model system was used to estimate the impacts of the usage of reformulated and alternative fuels on regional air quality with special emphasis on surface ozone concentrations. A severe western European summer smog episode in July 1994 has been used as a reference, and the model predictions have been evaluated for this episode. A forecast simulation for the year 2005 (TREND) has been performed, including the future emission development based on the current legislation and technologies available. The results of the scenario TREND are used as a baseline for the other 2005 fuel scenarios, including fuel reformulation, fuel sulfur content, and compressed natural gas (CNG) as an alternative fuel. Compared to the year 1994, significant reductions in episode peak ozone concentrations and ozone grid hours are predicted for the TREND scenario. These reductions are even more pronounced within the investigated alternative and reformulated fuel scenarios. Especially, low sulfur fuels are appropriate for an immediate improvement in air quality, because they effect the emissions of the whole fleet. Furthermore, the simulation results indicate that the introduction of CNG vehicles would also enhance air quality with respect to ozone.

  13. Biogeography in Cellana (Patellogastropoda, Nacellidae with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species.

    Directory of Open Access Journals (Sweden)

    Claudio A González-Wevar

    Full Text Available Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus.

  14. An Enthusiastic Glance in to the Visible Responsive Photocatalysts for Energy Production and Pollutant Removal, with Special Emphasis on Titania

    Directory of Open Access Journals (Sweden)

    Padikkaparambil Silija

    2012-01-01

    Full Text Available As a consequence of the rapid growth of industry, major problems are created related to energy and environment. Sunlight being one of the most potential alternative source of energy, the development of efficient solar-energy storage systems is an important subject in the fields of science and technology. Here we have reviewed and summarized some of the recent reports on visible responsive photocatalysts. In this review, the influence of various metal oxide photocatalysts on energy production and pollutant removal are presented with special emphasis on titania based photocatalysts. The photoactivity of titania for various pollutant degradation, modified titania (TiO2 systems, their physical and chemical characteristics, and so forth, are described in detail at this juncture. Different methods used to enhance the visible light absorption of TiO2, like doping with metals and nonmetals, coupling with other metal oxides, and so forth, have been discussed. Various applications of photocatalysts including photocatalytic treatment of waste water, pesticide degradation and water splitting to produce hydrogen are summarized. The development of photocatalysts that function under visible light for the efficient utilization of sunlight is an area of current interest and thus the different methods of preparation for the visible active photocatalysts are also explored.

  15. Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species

    Science.gov (United States)

    Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

    2017-01-01

    Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus. PMID:28099466

  16. Current drug therapy of patients with BPH-LUTS with the special emphasis on PDE5 inhibitors.

    Science.gov (United States)

    Kolontarev, Konstantin; Govorov, Alexander; Kasyan, George; Priymak, Diana; Pushkar, Dmitry

    2016-01-01

    Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptom (LUTS) development in men [1]. The intensity of the symptoms may vary from mild to severe, significantly affecting the quality of life. Erectile dysfunction (ED) is one of the most challenging issues in modern urology that significantly influences the quality of life in men worldwide. The objective of this literature review was to analyze the current drug therapies of patients with BPH-LUTS, with the special emphasis on PDE5 inhibitors. The authors searched the literature for the period from 2000 until 2015 in MEDLINE and PubMed. Twenty-three articles were selected based on their reliability. A detailed analysis of the selected papers was performed. Primary attention was given to articles describing the use of PDE5. Works describing the use of different groups of drugs in patients with BPH-LUTS were also selected. The current literature analysis suggests that the introduction of PDE5 inhibitors in clinical practice for the treatment of patients with BPH-LUTS will allow for significant expansion of the therapeutic options for the treatment of this disease.

  17. A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata)

    Science.gov (United States)

    2011-01-01

    Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp. have since been isolated from a variety of marine mammals. Pathological changes, including lesions of the reproductive organs and associated abortions, have only been registered in cetaceans. The zoonotic potential differs among the marine mammal Brucella strains. Many techniques, both classical typing and molecular microbiology, have been utilised for characterisation of the marine mammal Brucella spp. and the change from the band-based approaches to the sequence-based approaches has greatly increased our knowledge about these strains. Several clusters have been identified within the B. ceti and B. pinnipedialis species, and multiple studies have shown that the hooded seal isolates differ from other pinniped isolates. We describe how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates. We further discuss the potential role of B. pinnipedialis for the declining Northwest Atlantic hooded seal population. PMID:21819589

  18. A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata

    Directory of Open Access Journals (Sweden)

    Nymo Ingebjørg H

    2011-08-01

    Full Text Available Abstract Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp. have since been isolated from a variety of marine mammals. Pathological changes, including lesions of the reproductive organs and associated abortions, have only been registered in cetaceans. The zoonotic potential differs among the marine mammal Brucella strains. Many techniques, both classical typing and molecular microbiology, have been utilised for characterisation of the marine mammal Brucella spp. and the change from the band-based approaches to the sequence-based approaches has greatly increased our knowledge about these strains. Several clusters have been identified within the B. ceti and B. pinnipedialis species, and multiple studies have shown that the hooded seal isolates differ from other pinniped isolates. We describe how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates. We further discuss the potential role of B. pinnipedialis for the declining Northwest Atlantic hooded seal population.

  19. Treatment of antimony mine drainage: challenges and opportunities with special emphasis on mineral adsorption and sulfate reducing bacteria.

    Science.gov (United States)

    Li, Yongchao; Hu, Xiaoxian; Ren, Bozhi

    2016-01-01

    The present article summarizes antimony mine distribution, antimony mine drainage generation and environmental impacts, and critically analyses the remediation approach with special emphasis on iron oxidizing bacteria and sulfate reducing bacteria. Most recent research focuses on readily available low-cost adsorbents, such as minerals, wastes, and biosorbents. It is found that iron oxides prepared by chemical methods present superior adsorption ability for Sb(III) and Sb(V). However, this process is more costly and iron oxide activity can be inhibited by plenty of sulfate in antimony mine drainage. In the presence of sulfate reducing bacteria, sulfate can be reduced to sulfide and form Sb(2)S(3) precipitates. However, dissolved oxygen and lack of nutrient source in antimony mine drainage inhibit sulfate reducing bacteria activity. Biogenetic iron oxide minerals from iron corrosion by iron-oxidizing bacteria may prove promising for antimony adsorption, while the micro-environment generated from iron corrosion by iron oxidizing bacteria may provide better growth conditions for symbiotic sulfate reducing bacteria. Finally, based on biogenetic iron oxide adsorption and sulfate reducing bacteria followed by precipitation, the paper suggests an alternative treatment for antimony mine drainage that deserves exploration.

  20. 24. MPA-seminar: safety and reliability of plant technology with special emphasis on integrity and life management. Vol. 1. Papers 1-27

    International Nuclear Information System (INIS)

    1999-01-01

    The first volume is dedicated to the safety and reliability of plant technology with special emphasis on the integrity and life management. The main topic in the volume is the contribution of nondestructive testing to the reactor safety from an international point of view. All 20 papers are separately analyzed for this database. (orig.)

  1. 24. MPA-seminar: safety and reliability of plant technology with special emphasis on integrity and life management. Vol. 2. Papers 28-63

    International Nuclear Information System (INIS)

    1999-01-01

    The second volume is dedicated to the safety and reliability of plant technology with special emphasis on the integrity and life management. The following topics are discussed: 1. Integrity of vessels, pipes and components. 2. Fracture mechanics. 3. Measures for the extension of service life, and 4. Online Monitoring. All 30 contributions are separately analyzed for this database. (orig.)

  2. Seasonal dynamics of zooplankton in Columbia–Snake River reservoirs,with special emphasis on the invasive copepod Pseudodiaptomus forbesi

    Science.gov (United States)

    Emerson, Joshua E.; Bollens, Stephen M.; Counihan, Timothy D.

    2015-01-01

    The Asian copepod Pseudodiaptomus forbesi has recently become established in the Columbia River. However, little is known about its ecology and effects on invaded ecosystems. We undertook a 2-year (July 2009 to June 2011) field study of the mesozooplankton in four reservoirs in the Columbia and Snake Rivers, with emphasis on the relation of the seasonal variation in distribution and abundance of P. forbesi to environmental variables. Pseudodiaptomus forbesi was abundant in three reservoirs; the zooplankton community of the fourth reservoir contained no known non-indigenous taxa. The composition and seasonal succession of zooplankton were similar in the three invaded reservoirs: a bloom of rotifers occurred in spring, native cyclopoid and cladoceran species peaked in abundance in summer, and P. forbesi was most abundant in late summer and autumn. In the uninvaded reservoir, total zooplankton abundance was very low year-round. Multivariate ordination indicated that temperature and dissolved oxygen were strongly associated with zooplankton community structure, with P. forbesi appearing to exhibit a single generation per year . The broad distribution and high abundance of P. forbesi in the Columbia–Snake River System could result in ecosystem level effects in areas intensively managed to improve conditions for salmon and other commercially and culturally important fish species. 

  3. Study of the Knowledge, Attitude and Experience of Medical Tourism Among Target Groups with Special Emphasis on South India

    Directory of Open Access Journals (Sweden)

    Rajeev A

    2009-09-01

    Full Text Available Medical tourism aims at providing cost-effective customized health care in collaboration with the tourism industry in distant locations wherein the hospitality component is handled efficiently so that fixing appointments, making arrangements for accommodation and other logistics become hassle-free for the patient. This allows more concentration on the procedure at hand and the interaction between the medical fraternity and the patient becomes smoother. More and more hospitals in India are gearing up to provide such services to neighbouring countries and even to the developed nations across the world. The purpose of this study was to study the knowledge, attitude and experiences of the population of a suitable cross-section regarding the emerging scenario of medical tourism with special interest vis-à-vis Non Resident Indians (NRIs specifically to the state of Karnataka and Mangalore in particular. It was found that compared to the locals (kannadigas or non-kannadigas, the Non-resident Indians were more dissatisfied with the health care facilities available in their proximity. Though a majority of them do have medical insurance, it still looks as if the care is more cost-effective when sourced to India. NRIs are more aware of the potential of medical tourism through their communication with the medical fraternity as well as the general public and 11.1% of NRIs have really utilized the services of medical tourism. An e-mail survey which was also conducted among a number of foreigners yielded the interesting fact that they indeed had a greater awareness regarding medical tourism with an emphasis on health tourism. The reason why these foreigners opted for medical tourism was due to the substandard medical care available in their locality, rather than due to the cost of medical care as such.

  4. Survey of Staphylococcus isolates among hospital personnel, environment and their antibiogram with special emphasis on methicillin resistance

    Directory of Open Access Journals (Sweden)

    Shobha K

    2005-01-01

    Full Text Available The objective of this study was to find the prevalence of Staphylococcus spp. carriage among hospital personnel and hospital environment and their antibiogram with special emphasis on methicillin resistance. A total of 205 samples from hospital personnel and environment were collected from casualty, oncology and multidisciplinary cardiac unit ward of Kasturba Medical College Hospital, Manipal. Samples were collected using sterile cotton wool swabs and inoculated into brain heart infusion broth. Subcultures were done onto blood agar and MacConkey′s agar. Isolates were identified by standard methods up to species level. Antimicrobial susceptibility test was performed according to standardized disc diffusion Kirby-Bauer method. Each of the isolates was screened for methicillin resistance using oxacillin disc on Mueller Hinton agar plate followed by MIC for methicillin and cefoxitin susceptibility test by disc diffusion method. Sixty five out of 205 strains (31.7% were Staphylococcus spp. and all of them were coagulase negative. Most of the strains belonged to S.epidermidis 49.23%(32/65 followed by S. saprophyticus 26.15%(17/65. Maximum isolates of S.epidermidis were from anterior nares 28.12%(9/32 strains of S.epidermidis . Highest number of methicillin resistant coagulase negative strains (3/9, 33.33% were isolated from stethoscope of multidisciplinary cardiac unit ward followed by carriers in the anterior nares (2/9, 22.22%. Methicillin resistant coagulase negative staphylococci are prevalent in anterior nares of hospital personnel and in the hospital environment thereby providing a definite source for hospital acquired infection. All isolates were sensitive to vancomycin, ciprofloxacin and amikacin.

  5. Integrated plant nutrient system - with special emphasis on mineral nutriton and biofertilizers for Black pepper and cardamom - A review.

    Science.gov (United States)

    K P, Sangeeth; R, Suseela Bhai

    2016-05-01

    Integrated Plant Nutrition System (IPNS) as a concept and farm management strategy embraces and transcends from single season crop fertilization efforts to planning and management of plant nutrients in crop rotations and farming systems on a long-term basis for enhanced productivity, profitability and sustainability. It is estimated that about two-thirds of the required increase in crop production in developing countries will have to come from yield increases from lands already under cultivation. IPNS enhances soil productivity through a balanced use of soil nutrients, chemical fertilizers, combined with organic sources of plant nutrients, including bio-inoculants and nutrient transfer through agro-forestry systems and has adaptation to farming systems in both irrigated and rainfed agriculture. Horticultural crops, mainly plantation crops, management practices include application of fertilizers and pesticides which become inevitable due to the depletion of soil organic matter and incidence of pests and diseases. The extensive use of chemical fertilizers in these crops deteriorated soil health that in turn affected the productivity. To revitalize soil health and to enhance productivity, it is inexorable to enrich the soil using microorganisms. The lacunae observed here is the lack of exploitation of indigenous microbes having the potential to fix atmospheric nitrogen (N) and to solubilize Phosphorus (P) and Potassium (K). The concept of biofertilizer application appears to be technically simple and financially feasible, but the task of developing biofertilizers with efficient strains in appropriate combinations in a consortia mode is not easier. More than developing consortia, a suitable delivery system to discharge the microbial inoculants warranted much effort. This review focuses on the integrated plant nutrition system incorporating biofertilizer with special emphasis on developing and formulating biofertilizer consortium.

  6. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells

    International Nuclear Information System (INIS)

    Manda, Katrin; Glasow, Annegret; Paape, Daniel; Hildebrandt, Guido

    2012-01-01

    Dendritic cells (DCs), as professional antigen-presenting cells, are members of the innate immune system and function as key players during the induction phase of adaptive immune responses. Uptake, processing, and presentation of antigens direct the outcome toward either tolerance or immunity. The cells of the immune system are among the most highly radiosensitive cells in the body. For high doses of ionizing radiation (HD-IR) both immune-suppressive effects after whole body irradiation and possible immune activation during tumor therapy were observed. On the other hand, the effects of low doses of ionizing radiation (LD-IR) on the immune system are controversial and seem to show high variability among different individuals and species. There are reports revealing that protracted LD-IR can result in radioresistance. But immune-suppressive effects of chronic LD-IR are also reported, including the killing or sensitizing of certain cell types. This article shall review the current knowledge of radiation-induced effects on the immune system, paying special attention to the interaction of DCs and T cells.

  7. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells

    Energy Technology Data Exchange (ETDEWEB)

    Manda, Katrin [Department of Radiotherapy and Radiation Oncology, University of Rostock, Rostock (Germany); Glasow, Annegret [Department of Radiotherapy and Radiation Oncology, University of Leipzig, Leipzig (Germany); Paape, Daniel; Hildebrandt, Guido, E-mail: guido.hildebrandt@uni-rostock.de [Department of Radiotherapy and Radiation Oncology, University of Rostock, Rostock (Germany)

    2012-08-24

    Dendritic cells (DCs), as professional antigen-presenting cells, are members of the innate immune system and function as key players during the induction phase of adaptive immune responses. Uptake, processing, and presentation of antigens direct the outcome toward either tolerance or immunity. The cells of the immune system are among the most highly radiosensitive cells in the body. For high doses of ionizing radiation (HD-IR) both immune-suppressive effects after whole body irradiation and possible immune activation during tumor therapy were observed. On the other hand, the effects of low doses of ionizing radiation (LD-IR) on the immune system are controversial and seem to show high variability among different individuals and species. There are reports revealing that protracted LD-IR can result in radioresistance. But immune-suppressive effects of chronic LD-IR are also reported, including the killing or sensitizing of certain cell types. This article shall review the current knowledge of radiation-induced effects on the immune system, paying special attention to the interaction of DCs and T cells.

  8. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells.

    Science.gov (United States)

    Manda, Katrin; Glasow, Annegret; Paape, Daniel; Hildebrandt, Guido

    2012-01-01

    Dendritic cells (DCs), as professional antigen-presenting cells, are members of the innate immune system and function as key players during the induction phase of adaptive immune responses. Uptake, processing, and presentation of antigens direct the outcome toward either tolerance or immunity. The cells of the immune system are among the most highly radiosensitive cells in the body. For high doses of ionizing radiation (HD-IR) both immune-suppressive effects after whole body irradiation and possible immune activation during tumor therapy were observed. On the other hand, the effects of low doses of ionizing radiation (LD-IR) on the immune system are controversial and seem to show high variability among different individuals and species. There are reports revealing that protracted LD-IR can result in radioresistance. But immune-suppressive effects of chronic LD-IR are also reported, including the killing or sensitizing of certain cell types. This article shall review the current knowledge of radiation-induced effects on the immune system, paying special attention to the interaction of DCs and T cells.

  9. An In-Depth Review of the Current Practica, Associated with Early Childhood through Twelfth Grade Special Education Programs, for the Benefit of Higher Education Programs, with an Emphasis in Obtaining a M.Ed. in Special Education

    Science.gov (United States)

    Cady, Jennifer

    2010-01-01

    In order to guide organizational growth in the Master's in Education with an emphasis in Special Education program, offered at Southwestern College, an in-depth qualitative study was conducted with participants from three specific realms located in the state of Kansas. Participants from the Kansas State Department of Education, Southwestern…

  10. Object-oriented design and programming with C++ your hands-on guide to C++ programming, with special emphasis on design, testing, and reuse

    CERN Document Server

    Leach, Ronald

    2014-01-01

    Object-Oriented Design and Programming with C++: Your Hands-On Guide to C++ Programming, with Special Emphasis on Design, Testing, and Reuse provides a list of software engineering principles to guide the software development process. This book presents the fundamentals of the C++ language.Organized into two parts encompassing 10 chapters, this book begins with an overview of C++ and describes object-oriented programming and the history of C++. This text then introduces classes, polymorphism, inheritance, and overloading. Other chapters consider the C++ preprocessor and organization of class l

  11. The Swedish final repository for reactor waste (SFR). A summary of the SFR project with special emphasis on the near-field assessments

    International Nuclear Information System (INIS)

    Carlsson, J.

    1988-01-01

    The first phase of the final repository for reactor waste (SFR) is scheduled for operation in April 1988. The construction work is finished and preoperational tests are in progress. Impact on the environment from SFR is analysed in a final safety report. This paper gives a summary of the design and performance of SFR. Assessments, made for the analysises of the long term safety, are given with special emphasis on the near-field. As a conclusion from the analysises, the dose commitment to the most affected individual during the post-closure period, has proved to constitute only an insignificant contribution to the natural radioactive environment of the area

  12. Safety and reliability of pressure components with special emphasis on the contribution of component and large specimen testing to structural integrity assessment methodology. Vol. 1 and 2

    International Nuclear Information System (INIS)

    1987-01-01

    The 51 papers of the 13. MPA-seminar contribute to structural integrity assessment methodology with special emphasis on the component and large specimen testing. 8 of the papers deal with fracture mechanics, 6 papers with dynamic loading, 13 papers with nondestructive testing, 2 papers with radiation embrittlement, 5 papers with pipe failure, 4 papers with components, 2 papers with thermal shock loading, 5 papers with the high temperature behaviour, 4 papers with the integrity of vessels and 3 papers with the integrity of welded joints. Especially also the fracture behaviour of steel material is verificated. All papers are separately indexed and analysed for the database. (DG) [de

  13. Preliminary ecological study of plant species of Lokame Natural Forest (Nord Ubangi Province, Democratic Republic of the Congo): A special emphasis on Non-timber Forest Products

    OpenAIRE

    Koto-te-Nyiwa Ngbolua,

    2017-01-01

    A preliminary ecological study with a special emphasis on Non-timber forest products (NTFPs) was conducted between 2014 and 2015 on both anks of Lokame River in Lokame forest. The results showed that the Lokame natural forest has a very rich and diversified in NTFPs. Data collected over a total area of 2 ha identified 20 families and 25 different plant species producing NTFPs and 914 individuals, of which 39% are food, 38% for different uses, 14% for aphrodisiacs and 9% as medicinal. A compar...

  14. Guest editorial for the special issue ‘‘Tectonics of Bay of Bengal and Arabian Sea with special emphasis on coastal and marine geohazards’’

    Digital Repository Service at National Institute of Oceanography (India)

    Murthy, K.S.R.; Chaubey, A.K.; Radhakrishna, M.

    selected for this special issue. These include five papers dealing with various aspects of seismogenesis, structural heterogeneity and tsunami-related studies in the Andaman-Sumatra region, one paper on 3D seismic structure in Kachchh region affected...

  15. Additions to the annotated list of marine alien biota in the Mediterranean with special emphasis on Foraminifera and Parasites

    Directory of Open Access Journals (Sweden)

    A. ZENETOS

    2008-05-01

    Full Text Available The present work is an update of the annotated list (ZENETOS et al., 2006 based on literature up to April 2008. Emphasis is given to ecofunctional/taxonomic groups poorly addressed in the annotated list, such as the foraminiferan and parasites, while macrophytes are critically reviewed following the CIESM Atlas (VERLAQUE et al., in press. Moreover, in this update the bio-geographic area addressed includes the Sea of Marmara. The update yields a further 175 alien species in the Mediterranean bringing the total to 903. As evidenced by recent findings, more and more previously known ‘casual’ aliens, are becoming established. Approximately 100 more species have become well established in the region, raising the number of established species to 496 versus 385 until 2005. In the period from January 2006 to April 2008 more than 80 published papers have resulted in the recording of 94 new aliens, which is interpreted as a new introduction every 9 days, a rate beyond the worst scenario.

  16. Determinants of the renin-angiotensin-aldosterone system in cirrhosis with special emphasis on the central blood volume

    DEFF Research Database (Denmark)

    Møller, Søren; Bendtsen, Flemming; Henriksen, Jens H

    2006-01-01

    OBJECTIVE: Several studies have shown activation of the renin-angiotensin-aldosterone system (RAAS) in cirrhosis. Although the activated RAAS may have several determinants, the system is often considered a surrogate marker of effective hypovolaemia. In this study we investigated the activity...... of the RAAS and its potential determinants with special focus on the central and arterial blood volume (CBV). MATERIAL AND METHODS: Eighty-nine patients (Child class A/B/C: 19/41/29) and 32 controls were included in the study. All were given a haemodynamic examination with measurement of determinants...

  17. 23. MPA-Seminar: Safety and reliability of plant technology with special emphasis on behaviour of pressurized components and systems at increased loading. Vol. 1. Papers 1-26

    International Nuclear Information System (INIS)

    1998-01-01

    This book is dedicated to the components of nuclear and conventional power plants with special emphasis on the behaviour of pressurized components and systems. The following topics are discussed: 1. integrity of pipes, vessels, and components and 2. fracture mechanics

  18. MAGIC MOORE-PENROSE INVERSES AND PHILATELIC MAGIC SQUARES WITH SPECIAL EMPHASIS ON THE DANIELS–ZLOBEC MAGIC SQUARE

    Directory of Open Access Journals (Sweden)

    Ka Lok Chu

    2011-02-01

    Full Text Available We study singular magic matrices in which the numbers in the rows and columns and in the two main diagonals all add up to the same sum. Our interest focuses on such magic matrices for which the Moore–Penrose inverse is also magic. Special attention is given to the “Daniels–Zlobec magic square’’ introduced by the British magician and television performer Paul Daniels (b. 1938 and considered by Zlobec (2001; see also Murray (1989, pp. 30–32. We introduce the concept of a “philatelic magic square” as a square arrangement of images of postage stamps so that the associated nominal values form a magic square. Three philatelic magic squares with stamps especially chosen for Sanjo Zlobec are presented in celebration of his 70th birthday; most helpful in identifying these stamps was an Excel checklist by Männikkö (2009.

  19. Phylogeny, biogeography and character evolution in the tribe Desmodieae (Fabaceae: Papilionoideae), with special emphasis on the New Caledonian endemic genera.

    Science.gov (United States)

    Jabbour, Florian; Gaudeul, Myriam; Lambourdière, Josie; Ramstein, Guillaume; Hassanin, Alexandre; Labat, Jean-Noël; Sarthou, Corinne

    2018-01-01

    The nearly cosmopolitan tribe Desmodieae (Fabaceae) includes many important genera for medicine and forage. However, the phylogenetic relationships among the infratribal groups circumscribed using morphological traits are still poorly known. In this study, we used chloroplast (rbcL, psbA-trnH) and nuclear (ITS-1) DNA sequences to investigate the molecular phylogeny and historical biogeography of Desmodieae, and infer ancestral states for several vegetative and reproductive traits. Three groups, corresponding to the Desmodium, Lespedeza, and Phyllodium groups sensu Ohashi were retrieved in the phylogenetic analyses. Conflicts in the topologies inferred from the chloroplast and nuclear datasets were detected. For instance, the Lespedeza clade was sister to the groups Phyllodium+Desmodium based on chloroplast DNA, but nested within the Desmodium group based on ITS-1. Moreover, the New Caledonian endemic genera Arthroclianthus and Nephrodesmus were not monophyletic but together formed a clade, which also included Hanslia and Ohwia based on chloroplast DNA. The hypothetical common ancestor of Desmodieae was dated to the Middle Oligocene (ca. 28.3Ma) and was likely an Asian shrub or tree producing indehiscent loments. Several colonization events towards Oceania, America, and Africa occurred (all less than ca. 17.5Ma), most probably through long distance dispersal. The fruits of Desmodieae repeatedly evolved from indehiscence to dehiscence. We also showed that indehiscent loments allow for more variability in the number of seeds per fruit than indehiscent legumes. Modularity seems here to allow variability in the number of ovules produced in a single ovary. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Wave power - Sustainable energy or environmentally costly? A review with special emphasis on linear wave energy converters

    Energy Technology Data Exchange (ETDEWEB)

    Langhamer, Olivia [Dept. of Animal Ecology, UU, Norbyvaegen 18D, S-75236 Uppsala (Sweden); Swedish Centre for Renewable Electric Energy Conversion, Division for Electricity, Aangstroem Laboratory, Uppsala University, Box 534, S-75121 Uppsala (Sweden); Haikonen, Kalle; Sundberg, Jan [Swedish Centre for Renewable Electric Energy Conversion, Division for Electricity, Aangstroem Laboratory, Uppsala University, Box 534, S-75121 Uppsala (Sweden)

    2010-05-15

    Generating electricity from waves is predicted to be a new source of renewable energy conversion expanding significantly, with a global potential in the range of wind and hydropower. Several wave power techniques are on the merge of commercialisation, and thus evoke questions of environmental concern. Conservation matters are to some extent valid independent of technique but we mainly focus on point absorbing linear generators. By giving examples from the Lysekil project, run by Uppsala University and situated on the Swedish west coast, we demonstrate ongoing and future environmental studies to be performed along with technical research and development. We describe general environmental aspects generated by wave power projects; issues also likely to appear in Environmental Impact Assessment studies. Colonisation patterns and biofouling are discussed with particular reference to changes of the seabed and alterations due to new substrates. A purposeful artificial reef design to specially cater for economically important or threatened species is also discussed. Questions related to fish, fishery and marine mammals are other examples of topics where, e.g. no-take zones, marine bioacoustics and electromagnetic fields are important areas. In this review we point out areas in which studies likely will be needed, as ventures out in the oceans also will give ample opportunities for marine environmental research in general and in areas not previously studied. Marine environmental and ecological aspects appear to be unavoidable for application processes and in post-deployment studies concerning renewable energy extraction. Still, all large-scale renewable energy conversion will cause some impact mainly by being area demanding. An early incorporation of multidisciplinary and high quality research might be a key for new ocean-based techniques. (author)

  1. Heavy metal concentrations in soils as determined by laser-induced breakdown spectroscopy (LIBS), with special emphasis on chromium

    International Nuclear Information System (INIS)

    Senesi, G.S.; Dell'Aglio, M.; Gaudiuso, R.; De Giacomo, A.; Zaccone, C.; De Pascale, O.; Miano, T.M.; Capitelli, M.

    2009-01-01

    Soil is unanimously considered as one of the most important sink of heavy metals released by human activities. Heavy metal analysis of natural and polluted soils is generally conducted by the use of atomic absorption spectroscopy (AAS) or inductively coupled plasma optical emission spectroscopy (ICP-OES) on adequately obtained soil extracts. Although in recent years the emergent technique of laser-induced breakdown spectroscopy (LIBS) has been applied widely and with increasing success for the qualitative and quantitative analyses of a number of heavy metals in soil matrices with relevant simplification of the conventional methodologies, the technique still requires further confirmation before it can be applied fully successfully in soil analyses. The main objective of this work was to demonstrate that new developments in LIBS technique are able to provide reliable qualitative and quantitative analytical evaluation of several heavy metals in soils, with special focus on the element chromium (Cr), and with reference to the concentrations measured by conventional ICP spectroscopy. The preliminary qualitative LIBS analysis of five soil samples and one sewage sludge sample has allowed the detection of a number of elements including Al, Ca, Cr, Cu, Fe, Mg, Mn, Pb, Si, Ti, V and Zn. Of these, a quantitative analysis was also possible for the elements Cr, Cu, Pb, V and Zn based on the obtained linearity of the calibration curves constructed for each heavy metal, i.e., the proportionality between the intensity of the LIBS emission peaks and the concentration of each heavy metal in the sample measured by ICP. In particular, a triplet of emission lines for Cr could be used for its quantitative measurement. The consistency of experiments made on various samples was supported by the same characteristics of the laser-induced plasma (LIP), i.e., the typical linear distribution confirming the existence of local thermodynamic equilibrium (LTE) condition, and similar excitation

  2. Heavy metal concentrations in soils as determined by laser-induced breakdown spectroscopy (LIBS), with special emphasis on chromium.

    Science.gov (United States)

    Senesi, G S; Dell'Aglio, M; Gaudiuso, R; De Giacomo, A; Zaccone, C; De Pascale, O; Miano, T M; Capitelli, M

    2009-05-01

    Soil is unanimously considered as one of the most important sink of heavy metals released by human activities. Heavy metal analysis of natural and polluted soils is generally conducted by the use of atomic absorption spectroscopy (AAS) or inductively coupled plasma optical emission spectroscopy (ICP-OES) on adequately obtained soil extracts. Although in recent years the emergent technique of laser-induced breakdown spectroscopy (LIBS) has been applied widely and with increasing success for the qualitative and quantitative analyses of a number of heavy metals in soil matrices with relevant simplification of the conventional methodologies, the technique still requires further confirmation before it can be applied fully successfully in soil analyses. The main objective of this work was to demonstrate that new developments in LIBS technique are able to provide reliable qualitative and quantitative analytical evaluation of several heavy metals in soils, with special focus on the element chromium (Cr), and with reference to the concentrations measured by conventional ICP spectroscopy. The preliminary qualitative LIBS analysis of five soil samples and one sewage sludge sample has allowed the detection of a number of elements including Al, Ca, Cr, Cu, Fe, Mg, Mn, Pb, Si, Ti, V and Zn. Of these, a quantitative analysis was also possible for the elements Cr, Cu, Pb, V and Zn based on the obtained linearity of the calibration curves constructed for each heavy metal, i.e., the proportionality between the intensity of the LIBS emission peaks and the concentration of each heavy metal in the sample measured by ICP. In particular, a triplet of emission lines for Cr could be used for its quantitative measurement. The consistency of experiments made on various samples was supported by the same characteristics of the laser-induced plasma (LIP), i.e., the typical linear distribution confirming the existence of local thermodynamic equilibrium (LTE) condition, and similar excitation

  3. Quantitative estimates of dietary intake with special emphasis on snacking pattern and nutritional status of free living adults in urban slums of Delhi: impact of nutrition transition.

    Science.gov (United States)

    Singh, Archna; Gupta, Vidhu; Ghosh, Arpita; Lock, Karen; Ghosh-Jerath, Suparna

    2015-10-14

    The nutritional landscape of India is experiencing the fallout of urbanization and globalization. The changes are manifest in dietary patterns as well as health outcomes. The study aimed at assessing household dietary intake pattern with special emphasis on snacking pattern, anthropometric and lipid profiles in low socio-economic status households in an urban slum of Delhi. Community based cross-sectional study in 260 households of a purposively selected urban slum in North-East district of Delhi, India. Family dietary surveys including consumption pattern of commercial food products rich in Partially Hydrogenated Vegetable Oils (PHVOs), 24 h dietary recall and assessment of dietary diversity using Household Diet Diversity Scores (HDDS) were done. Assessment of nutritional status using anthropometric and lipid profile on a subsample ( n =130) were also conducted. Median energy and fat intake were adequate. Micronutrient intake was found to be inadequate for vitamin A, riboflavin, calcium and folate. PHVO usage was low (healthy diet and lifestyle practices with emphasis on quantity and quality of nutrient intake. This must be considered as an integral part of chronic disease prevention strategy for underprivileged communities in urban India.

  4. The Radiation Response of Sarcomas by Histologic Subtypes: A Review With Special Emphasis Given to Results Achieved With Razoxane

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available Purpose. Relatively few results are available in the literature about the radiation response of unresectable sarcomas in relation to their histology. Therefore, an attempt was made to summarize the present situation. Materials and methods. This report is based on a review of the literature and the author's own experience. Adult-type soft tissue sarcomas, chondrosarcomas, and chordomas were analyzed. Radioresponse was mainly associated with the degree of tumor shrinkage, that is, objective responses. Histopathologic responses, that is, the degree of necrosis, are only discussed in relation to radiation treatment reports of soft tissue sarcomas as a group. Results. Radiation therapy alone leads to major responses in about 50% of lipo-, fibro-, leiomyo-, or chondrosarcomas. The response rate is less than 50% in malignant fibrous histiocytomas, synovial, neurogenic, and other rare soft tissue sarcomas. The response rates may increase up to 75% through the addition of radiosensitizers such as halogenated pyrimidines or razoxane, or by the use of high-LET irradiation. Angiosarcomas become clearly more responsive if biologicals, angiomodulating, and/or tubulin affinic substances are given together with radiation therapy. Razoxane is able to increase the duration and quality of responses even in difficult-to-treat tumors like chondrosarcomas or chordomas. Conclusions. The available data demonstrate that the radioresponsiveness of sarcomas is very variable and dependent on histology, kind of radiation, and various concomitantly given drugs. The rate of complete sustained remissions by radiation therapy alone or in combination with drugs is still far from satisfactory although progress has been made through the use of sensitizing agents.

  5. Development of an Estimating Procedure for the Annual PLAN Process - with Special Emphasis on the Estimating Group

    International Nuclear Information System (INIS)

    Lichtenberg, Steen

    2003-01-01

    matters, and finally (3) correct and transparent statistical calculations of the result. The resulting proposals for a new procedure include a model structure for the analysis team and its procedures, the initial identification and handling of the sources of uncertainty, a choice of scenarios and alternatives to be examined, followed by some quantification phases, during which the data on timing, costs, etc. are evaluated and followed by a calculation. The result consists of information about the necessary size of the fee rates for various degrees of safety or probability, as well as the primary sources of the remaining uncertainty involved. A workable procedure is always achieved through a balance between complying strictly with the relevant natural laws and being sufficiently simple and intelligible, with a minimum of 'black boxes'. The relevance of the desired balance is discussed and verification is attempted. Special attention is given to a discussion on the application of the Bayesian statistical theory, the paradigm of which is still new to some professionals and decision-makers. The procedure has been tested in several steps. So far, the procedure has lived up to or exceeded expectations. Some primary conclusions are summarised in the final chapter. More tests will be required. The results of this testing are to be published separately

  6. The Implications of Demographic Variables as Related to Burnout among a Sample of Special Education Teachers

    Science.gov (United States)

    Williams, Joy; Dikes, Catherine

    2015-01-01

    The attrition rate of highly qualified special education teachers is a pervasive problem in the United States. This study investigated the association between the burnout subscales of emotional exhaustion, depersonalization, and personal accomplishment relative to 10 demographic variables. Sixty-five special education teachers constituted the…

  7. Variable mycorrhizal benefits on the reproductive output of Geranium sylvaticum, with special emphasis on the intermediate phenotype.

    Science.gov (United States)

    Varga, S; Kytöviita, M-M

    2014-03-01

    In several gynodioecious species, intermediate sex between female and hermaphrodite has been reported, but few studies have investigated fitness parameters of this intermediate phenotype. Here, we examined the interactions between plant sex and arbuscular mycorrhizal (AM) fungal species affecting the reproductive output of Geranium sylvaticum, a sexually polymorphic plant species with frequent intermediate sexes between females and hermaphrodites, using a common garden experiment. Flowering phenology, AM colonisation levels and several plant vegetative and reproductive parameters, including seed and pollen production, were measured. Differences among sexes were detected in flowering, fruit set, pollen production and floral size. The two AM species used in the present work had different effects on plant fitness parameters. One AM species increased female fitness through increasing seed number and seed mass, while the other species reduced seed mass in all sexes investigated. AM fungi did not affect intermediate and hermaphrodite pollen content in anthers. The three sexes in G. sylvaticum did not differ in their reproductive output in terms of total seed production, but hermaphrodites had potentially larger fathering ability than intermediates due to higher anther number. The ultimate female function--seed production--did not differ among the sexes, but one of the AM fungi used potentially decreased host plant fitness. In addition, in the intermediate sex, mycorrhizal symbiosis functioned similarly in females as in hermaphrodites. © 2013 German Botanical Society and The Royal Botanical Society of the Netherlands.

  8. Combined experimental and computational investigation of the cavitating flow in an orifice plate with special emphasis on surrogate-based optimization method

    International Nuclear Information System (INIS)

    Li, XianLin; Huang, Biao; Chen, Tairan; Liu, Ying; Qiu, Si Cong; Zhao, Jing

    2017-01-01

    We investigated the influence of geometrical parameters of the orifice plate on the cavitation structures, and optimized these parameters by using a surrogate-based model with special emphasis on the concentration of hydroxyl radical released. The results show that for the orifice plate of the hydrodynamic cavitation system, the possible location of the inception of the cavity spreads to throat and divergent section of the venturi geometry. Based on the surrogate model and global sensitivity assessment, the diameter of throat Dt and diameter of inlet Din significantly influenced the size of the cavity, while the length of throat Lt had little effect on both cavitation intensity and flow rate. It should be noted that when Lt is decreased, the size of cavity would be slightly decreased but the flow rate increased clearly. The increase of the diverging section is in favor of the size of cavity. By comparing the experimental measurements on the concentration of Methylene blue, the optimum geometry of the orifice plate for best cavitational activity is proposed

  9. Camel Diseases and Conditions in a Non-traditional Camel Keeping Area: A case study of Kajiado District With Special Emphasis on Trypanosomiasis

    International Nuclear Information System (INIS)

    Chemuliti, J.K.

    2002-01-01

    Camels in Kenya are raised in the lowlands of Semi-arid to arid areas of Northern Kenya. Some NGO's (PHI and Farm Africa) introduced some camels into the wetter Southern rangelands of Kenya, specifically in Kajiado in 1989. There is no information so far on the productivity of these animals in this new environment. The objective of this study was to collect data on disease and conditions in Kajiado district with special emphasis on trypanosomosis. Twenty-four herds of camels in three divisions of Kajiado, comprising of 324 animals, were clinically examined and blood as well as faecal samples collected for laboratory examination for haemoparasites, anaemia and helminths as well as other infections and ectoparasites. The mean trypanosome point prevalence was 7.2% although Magadi had the biggest prevalence of 26.4%, while the central division had the least, 1.3% PCV values were proportion to magnitude of infection. T. brucei/T. evansi were shown to be present in varying degrees. Tick infestation comprised of Boophilus, Rhipicephalus and Hyalomma in about 53% of the camels. Helminth infection was observed in about 51% of the camels comprising mainly Haemonchus, Trichosrongylus, Strongyloides and Oesophagostomum. There were also cases of Abscesses, diarrhoea, mange eye infections, wounds and mastitis. It was concluded that new management strategies for the camel in southern rangelands is desirable to counter possible new diseases as well as other challenges of productivity

  10. Combined experimental and computational investigation of the cavitating flow in an orifice plate with special emphasis on surrogate-based optimization method

    Energy Technology Data Exchange (ETDEWEB)

    Li, XianLin; Huang, Biao; Chen, Tairan; Liu, Ying; Qiu, Si Cong [School of Mechanical and Vehicular Engineering, Beijing Institute of Technology, Beijing (China); Zhao, Jing [China Academy of Launch Vehicle Technology, Beijing (China)

    2017-01-15

    We investigated the influence of geometrical parameters of the orifice plate on the cavitation structures, and optimized these parameters by using a surrogate-based model with special emphasis on the concentration of hydroxyl radical released. The results show that for the orifice plate of the hydrodynamic cavitation system, the possible location of the inception of the cavity spreads to throat and divergent section of the venturi geometry. Based on the surrogate model and global sensitivity assessment, the diameter of throat Dt and diameter of inlet Din significantly influenced the size of the cavity, while the length of throat Lt had little effect on both cavitation intensity and flow rate. It should be noted that when Lt is decreased, the size of cavity would be slightly decreased but the flow rate increased clearly. The increase of the diverging section is in favor of the size of cavity. By comparing the experimental measurements on the concentration of Methylene blue, the optimum geometry of the orifice plate for best cavitational activity is proposed.

  11. Linguistic explanation and domain specialization: a case study in bound variable anaphora.

    Science.gov (United States)

    Adger, David; Svenonius, Peter

    2015-01-01

    The core question behind this Frontiers research topic is whether explaining linguistic phenomena requires appeal to properties of human cognition that are specialized to language. We argue here that investigating this issue requires taking linguistic research results seriously, and evaluating these for domain-specificity. We present a particular empirical phenomenon, bound variable interpretations of pronouns dependent on a quantifier phrase, and argue for a particular theory of this empirical domain that is couched at a level of theoretical depth which allows its principles to be evaluated for domain-specialization. We argue that the relevant principles are specialized when they apply in the domain of language, even if analogs of them are plausibly at work elsewhere in cognition or the natural world more generally. So certain principles may be specialized to language, though not, ultimately, unique to it. Such specialization is underpinned by ultimately biological factors, hence part of UG.

  12. An effective method for finding special solutions of nonlinear differential equations with variable coefficients

    International Nuclear Information System (INIS)

    Qin Maochang; Fan Guihong

    2008-01-01

    There are many interesting methods can be utilized to construct special solutions of nonlinear differential equations with constant coefficients. However, most of these methods are not applicable to nonlinear differential equations with variable coefficients. A new method is presented in this Letter, which can be used to find special solutions of nonlinear differential equations with variable coefficients. This method is based on seeking appropriate Bernoulli equation corresponding to the equation studied. Many well-known equations are chosen to illustrate the application of this method

  13. 23. MPA-Seminar: Safety and reliability of plant technology with special emphasis on behaviour of pressurized components and systems at increased loading. Vol. 2. Papers 27-50

    International Nuclear Information System (INIS)

    1998-01-01

    This book is dedicated to the components of nuclear and conventional power plants with special emphasis on the behaviour of pressurized components and systems. The following topics are discussed: 1. structure and safety analysis, 2. aging phenomena, 3. nondestructive testing, and 4. optimization of in-service inspection

  14. Certain properties of some special functions of two variables and two indices

    International Nuclear Information System (INIS)

    Khan, Subuhi

    2002-07-01

    In this paper, we derive a result concerning eigenvector and eigenvalue for a quadratic combination of four operators defined on a Lie algebra of endomorphisms of a vector space. Further, using this result, we deduce certain properties of some special functions of two variables and two indices. (author)

  15. Variables separation of the spectral BRDF for better understanding color variation in special effect pigment coatings.

    Science.gov (United States)

    Ferrero, Alejandro; Rabal, Ana María; Campos, Joaquín; Pons, Alicia; Hernanz, María Luisa

    2012-06-01

    A type of representation of the spectral bidirectional reflectance distribution function (BRDF) is proposed that distinctly separates the spectral variable (wavelength) from the geometrical variables (spherical coordinates of the irradiation and viewing directions). Principal components analysis (PCA) is used in order to decompose the spectral BRDF in decorrelated spectral components, and the weight that they have at every geometrical configuration of irradiation/viewing is established. This method was applied to the spectral BRDF measurement of a special effect pigment sample, and four principal components with relevant variance were identified. These four components are enough to reproduce the great diversity of spectral reflectances observed at different geometrical configurations. Since this representation is able to separate spectral and geometrical variables, it facilitates the interpretation of the color variation of special effect pigments coatings versus the geometrical configuration of irradiation/viewing.

  16. Intestinal polyparasitism with special emphasis to soil-transmitted helminths among residents around Gilgel Gibe Dam, Southwest Ethiopia: a community based survey.

    Science.gov (United States)

    Mekonnen, Zeleke; Suleman, Sultan; Biruksew, Abdissa; Tefera, Tamirat; Chelkeba, Legese

    2016-11-23

    One third of the world population is estimated to be infected with intestinal parasites. The most affected people are children and the poor people living in tropics and subtropics. Polyparasitism (the concurrent infection with multiple intestinal parasite species) is found to be the norm among the same population although accurate estimate of its magnitude is unknown. It was found that polyparasitism might have a greater impact on morbidity than single species infection which might also increase susceptibility to other infections. Therefore, this study aimed at determining the prevalence and distribution of intestinal polyparasitism with special emphasis on Soil-Transmitted Helminths (STH) among residents around Gilgel Gibe dam located in Jimma zone of Oromia regional state, Ethiopia. A total of 1,021 participants were recruited in this study and provided stool samples for parasitological examination. Direct wet mount and Kato-Katz techniques were employed for stool examination. Pearson chi-square test was employed to assess the association of infection status and polyparasitism with gender and age group of the study participants. Five hundred thirty two individuals were infected with at least one parasite, providing the overall prevalence of 52.1%. Among positive individuals, 405 (76.1%), 114 (21.4%), and 13 (2.5%) individuals were infected with only one, two and three species of parasites, respectively. The overall prevalence of intestinal polyparasitism observed among the study participants was 12.4% (127/1,021). The predominant STH was hookworm, with a prevalence of 44.1%. Hookworm and Ascaris lumbricoides were the most frequently recorded combination in cases of polyparasitic infection. The study revealed that there was no significant difference in the distribution of polyparasitism with regard to age group and sex of the study participants (p > 0.05). The study indicated the presence of high prevalence of parasites as well as distribution of

  17. Intestinal polyparasitism with special emphasis to soil-transmitted helminths among residents around Gilgel Gibe Dam, Southwest Ethiopia: a community based survey

    Directory of Open Access Journals (Sweden)

    Zeleke Mekonnen

    2016-11-01

    Full Text Available Abstract Background One third of the world population is estimated to be infected with intestinal parasites. The most affected people are children and the poor people living in tropics and subtropics. Polyparasitism (the concurrent infection with multiple intestinal parasite species is found to be the norm among the same population although accurate estimate of its magnitude is unknown. It was found that polyparasitism might have a greater impact on morbidity than single species infection which might also increase susceptibility to other infections. Therefore, this study aimed at determining the prevalence and distribution of intestinal polyparasitism with special emphasis on Soil-Transmitted Helminths (STH among residents around Gilgel Gibe dam located in Jimma zone of Oromia regional state, Ethiopia. Methods A total of 1,021 participants were recruited in this study and provided stool samples for parasitological examination. Direct wet mount and Kato-Katz techniques were employed for stool examination. Pearson chi-square test was employed to assess the association of infection status and polyparasitism with gender and age group of the study participants. Results Five hundred thirty two individuals were infected with at least one parasite, providing the overall prevalence of 52.1%. Among positive individuals, 405 (76.1%, 114 (21.4%, and 13 (2.5% individuals were infected with only one, two and three species of parasites, respectively. The overall prevalence of intestinal polyparasitism observed among the study participants was 12.4% (127/1,021. The predominant STH was hookworm, with a prevalence of 44.1%. Hookworm and Ascaris lumbricoides were the most frequently recorded combination in cases of polyparasitic infection. The study revealed that there was no significant difference in the distribution of polyparasitism with regard to age group and sex of the study participants (p > 0.05. Conclusion The study indicated the presence of high

  18. Macular hole surgery: an analysis of risk factors for the anatomical and functional outcomes with a special emphasis on the experience of the surgeon

    Directory of Open Access Journals (Sweden)

    Jenisch TM

    2017-06-01

    Full Text Available Teresa M Jenisch,1 Florian Zeman,2 Michael Koller,2 David A Märker,1 Horst Helbig,1 Wolfgang A Herrmann1,3 1Department of Ophthalmology, 2Centre for Clinical Studies, University Hospital Regensburg, 3Department of Ophthalmology, St John of God Hospital, Regensburg, Germany Purpose: The aim of this study was to evaluate risk factors for the anatomical and functional outcomes of macular hole (MH surgery with special emphasis on the experience of the surgeon. Methods: A total of 225 surgeries on idiopathic MHs (IMHs performed by 6 surgeons with a mean follow-up period of 20.5 months were reviewed in this retrospective study. Outcome parameters focused on IMH closure, complications and visual acuity improvement. The results of MH surgeries performed by experienced surgeons were compared to those of surgeons in training. Results: The average MH size was 381 µm (standard deviation [SD]=168. Brilliant blue G (BBG for internal limiting membrane (ILM staining was used in 109 (48% eyes and indocyanine green (ICG in 116 (52% eyes. As endotamponade, 20% SF6 was used in 38 (17% cases, 16% C2F6 in 33 (15% cases and 16% C3F8 in 154 (68% cases. IMH closure was achieved in 194 eyes (86%. Mean preoperative visual acuity was 0.84 logarithm of the minimum angle of resolution (log MAR; SD=0.29, range: 0.3–1.5; surgery led to a mean improvement of 0.40 (SD=0.37 log MAR. Although the MH closure rate was the same using BBG or ICG for ILM peeling, visual acuity improvement was better in eyes peeled with BBG compared to eyes peeled with ICG (log MAR: BBG: 0.38 [95% CI: 0.32, 0.44] vs ICG: 0.48 [95% CI: 0.42, 0.54], P=0.029. Surgeons with previous experience in vitreoretinal surgery of ≥6 years achieved better visual outcomes compared to surgeons with 0–3 years of experience, regardless of the MH size, preoperative visual acuity, time to follow-up or dye used for ILM peeling (0–3 years [0.27, ∆log MAR] vs ≥6 years [0.43, ∆log MAR], P=0.009. Conclusion

  19. [High energy particle physics]: Progress report covering the five year period from August 1, 1984 to May 31, 1989 with special emphasis for the period of August 1, 1988 to May 31, 1989: Part 1

    International Nuclear Information System (INIS)

    1989-01-01

    In this document the High Energy Physics group reviews its accomplishments and progress during the past five years, with special emphasis for the past year and presents plans for continuing research during the next several years. During the last few years the effort of the experimental group has been divided approximately equally between fixed target physics and preparations for future collider experiments. The main emphasis of the theory group has been in the area of strong and electroweak phenomenology with an emphasis on hard scattering processes. With the recent creation of the Supercomputer Computations Research Institute, some work has also been done in the area of numerical simulations of condensed matter spin models and techniques for implementing numerical simulations on supercomputers

  20. VARIABILITY OF AMYLOSE AND AMYLOPECTIN IN WINTER WHEAT AND SELECTION FOR SPECIAL PURPOSES

    Directory of Open Access Journals (Sweden)

    Nikolina Weg Krstičević

    2015-06-01

    Full Text Available The aim of this study was to investigate the variability of amylose and amylopectin in 24 Croatian and six foreign winter wheat varieties and to detect the potential of these varieties for special purposes. Starch composition analysis was based on the separation of amylose and amylopectin and the determination of their amounts and ratios. Analysis of the amount of amylose and amylopectin determined statistically highly significant differences between the varieties. The tested varieties are mostly bread wheat of different quality which have the usual content of amylose and amylopectin. Some varieties were identified among them with high amylopectin and low amylose content and one variety with high amylose content. They have the potential in future breeding programs and selection for special purposes.

  1. Overview of P.I.E. techniques for L.W.R. fuels at Saclay hot cells with special emphasis on new apparatus and on mechanical testing

    International Nuclear Information System (INIS)

    Blanc, J.Y.; Hardy, J.L.; Trotabas, M.

    1990-01-01

    This paper describes the state-of-the-art in the Saclay hot cells for examining L.W.R. fuels. First, we present the classical path followed by a fuel rod in the laboratory, to begin with non-destructive testing. This is completed by destructive examinations, such as free volume determination and fission gases analyses, density measurement and metallographies including X-rays diffraction and microprobe (EPMA/WDX). These two last techniques enable the identification of elements and chemical nature of compounds which are present. We also perform mechanical tests on metallic components, on clads and guide-tubes (tensile tests, creep, burst or fatigue tests by internal pressure). Another apparatus is devoted to the study of irradiated clad behaviour during LOCA-type transients. In the second chapter, a particular emphasis is given to the developments in progress, or planned in the near future. This includes: (a) The implementation of a new non-destructive testing bench to inspect more fuel rods simultaneously. (b) A new image analyzer to be applied e.g. to hydrides analysis in the clad, or to the inspection of safety test fuel bundles. (c) As for mechanical testing, we describe here the tensile tests on clads or on guide-tubes, performed on longitudinal samples or ring samples

  2. 23. MPA-Seminar: Safety and reliability of plant technology with special emphasis on behaviour of pressurized components and systems at increased loading. Vol. 1. Papers 1-26; 23. MPA-Seminar: Sicherheit und Verfuegbarkeit in der Anlagentechnik mit dem Schwerpunkt Verhalten von druckfuehrenden Komponenten und Systemen bei erhoehten Belastungen. Bd. 1. Vortraege 1-26

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    This book is dedicated to the components of nuclear and conventional power plants with special emphasis on the behaviour of pressurized components and systems. The following topics are discussed: 1. integrity of pipes, vessels, and components and 2. fracture mechanics

  3. An Overview of Prognosis Health Management Research at Glenn Research Center for Gas Turbine Engine Structures With Special Emphasis on Deformation and Damage Modeling

    Science.gov (United States)

    Arnold, Steven M.; Goldberg, Robert K.; Lerch, Bradley A.; Saleeb, Atef F.

    2009-01-01

    Herein a general, multimechanism, physics-based viscoelastoplastic model is presented in the context of an integrated diagnosis and prognosis methodology which is proposed for structural health monitoring, with particular applicability to gas turbine engine structures. In this methodology, diagnostics and prognostics will be linked through state awareness variable(s). Key technologies which comprise the proposed integrated approach include (1) diagnostic/detection methodology, (2) prognosis/lifing methodology, (3) diagnostic/prognosis linkage, (4) experimental validation, and (5) material data information management system. A specific prognosis lifing methodology, experimental characterization and validation and data information management are the focal point of current activities being pursued within this integrated approach. The prognostic lifing methodology is based on an advanced multimechanism viscoelastoplastic model which accounts for both stiffness and/or strength reduction damage variables. Methods to characterize both the reversible and irreversible portions of the model are discussed. Once the multiscale model is validated the intent is to link it to appropriate diagnostic methods to provide a full-featured structural health monitoring system.

  4. An Overview of Prognosis Health Management Research at GRC for Gas Turbine Engine Structures With Special Emphasis on Deformation and Damage Modeling

    Science.gov (United States)

    Arnold, Steven M.; Goldberg, Robert K.; Lerch, Bradley A.; Saleeb, Atef F.

    2009-01-01

    Herein a general, multimechanism, physics-based viscoelastoplastic model is presented in the context of an integrated diagnosis and prognosis methodology which is proposed for structural health monitoring, with particular applicability to gas turbine engine structures. In this methodology, diagnostics and prognostics will be linked through state awareness variable(s). Key technologies which comprise the proposed integrated approach include 1) diagnostic/detection methodology, 2) prognosis/lifing methodology, 3) diagnostic/prognosis linkage, 4) experimental validation and 5) material data information management system. A specific prognosis lifing methodology, experimental characterization and validation and data information management are the focal point of current activities being pursued within this integrated approach. The prognostic lifing methodology is based on an advanced multi-mechanism viscoelastoplastic model which accounts for both stiffness and/or strength reduction damage variables. Methods to characterize both the reversible and irreversible portions of the model are discussed. Once the multiscale model is validated the intent is to link it to appropriate diagnostic methods to provide a full-featured structural health monitoring system.

  5. Attitude of the Italian general population towards prevention and screening of the most common tumors, with special emphasis on colorectal malignancies.

    Science.gov (United States)

    Domati, Federica; Travlos, Estratios; Cirilli, Claudia; Rossi, Giuseppina; Benatti, Piero; Marino, Massimiliano; Ponti, Giovanni; Vandelli, Maria; Valmori, Simone; Oursana, Amal; Pezzi, Annalisa; Ponz de Leon, Maurizio

    2009-06-01

    Screening and early diagnosis of cancer represent relatively recent tools in the long-lasting battle against tumors. If the American public opinion manifests its enthusiasm towards screening, the attitude of European is less well known. The purpose of the present study was to assess the level of knowledge and awareness of cancer screening (with particular emphasis on colorectal neoplasms) among middle-aged individuals. The study group consisted of 945 healthy individuals (489 men, 456 women, average age 57 +/- 12.4 years) who were asked to answer a series of questions about cancer screening and surveillance through a questionnaire presented by trained residents. Each interview lasted 20-30 min. Middle-aged Italians of both sexes seem to be aware of the fact that cancer is a frequent disease; moreover, many of the interviewed subjects believe almost all neoplasms are incurable. Diet, style of life, other environmental factors and familial factors are fully appreciated as relevant risk factors. The exact meaning of prevention was clear to less than half of the subjects. When various cancer sites were analyzed, the existence of preventive measures was well known for breast, cervical and prostate tumors, but their role was less clear for colorectal cancer. Only a fraction of the interviewed individuals were willing to undergo screening; the main reasons for refusal were lack of usefulness and fear of results. Among various tests, ultrasound and endoscopy were usually carried out in the presence of symptoms. Finally, multivariate analysis showed that the two factors significantly associated with the decision to undergo screening procedures were increasing age and level of education. The results of the study suggest that middle-aged Italian individuals, predominantly from Northern regions, have a correct perception of some aspects (frequency, risk factors) of cancer biology, whereas the knowledge of other aspects (outcome, prevention) remains poor or approximate. It

  6. Atmospheric radiative transfer in the UV: special emphasis on photolysis frequencies J(O1D) and J(NO2)

    International Nuclear Information System (INIS)

    Pfister, G.

    2000-11-01

    The amount of solar UV-radiation penetrating to the lower atmosphere and the Earth's surface is of special interest for biological as well as photochemical processes. The present work deals with theoretical (modeling) as well as experimental methods for investigating the interaction between solar radiation and the atmosphere. Two international model intercomparisons showed, that for cloudless conditions and provided that atmospheric and surface conditions are known, simulations agree to within about 5-10 % among one another as well as with measurements. Differences are strongly dependent on the wavelength and the solar zenith angle. The radiative transfer model was not only used for comprehensive sensitivity studies, but also for investigating and analyzing measurement methods as well as measured data. Two techniques, which were applied in frame of two aircraft campaigns, are dealt with in more detail in this work: filter radiometry and spectro radiometry. Analysis of the airborne measurements mainly concentrated on the influence of clouds on the radiation field in the atmosphere. (author)

  7. Probing the mystery of Chinese medicine meridian channels with special emphasis on the connective tissue interstitial fluid system, mechanotransduction, cells durotaxis and mast cell degranulation

    Directory of Open Access Journals (Sweden)

    Fung Peter

    2009-05-01

    Full Text Available Abstract This article hypothesizes that the Chinese medicine meridian system is a special channel network comprising of skin with abundant nerves and nociceptive receptors of various types, and deeper connective tissues inside the body with the flowing interstitial fluid system. These meridian channels provide efficient migratory tracks mainly due to durotaxis (also including chemotaxis for mast cells, fibroblasts and other cells to migrate and carry out a number of physiological functions. Acupuncture acting on meridian channel causes cytoskeletal remodeling through mechanotransduction, leading to regulation of gene expression and the subsequent production of related proteins. Also, stimulation on cell surface can trigger Ca2+ activities, resulting in a cascade of intra- and inter-cellular signaling. Moreover, nerve endings in the meridian channels interact with mast cells and induce the degranulation of these cells, leading to the release of many specific biomolecules needed for homeostasis, immune surveillance, wound healing and tissue repair. Acupoint along a meridian channel is a functional site to trigger the above functions with specificity and high efficiency.

  8. Inter-decadal modulation of ENSO teleconnections to the Indian Ocean in a coupled model: Special emphasis on decay phase of El Niño

    Science.gov (United States)

    Chowdary, J. S.; Parekh, Anant; Gnanaseelan, C.; Sreenivas, P.

    2014-01-01

    Inter-decadal modulation of El Niño-Southern Oscillation (ENSO) teleconnections to tropical Indian Ocean (TIO) is investigated in the coupled general circulation model Climate Forecast System (CFS) using a hundred year integration. The model is able to capture the periodicity of El Niño variability, which is similar to that of the observations. The maximum TIO/north Indian Ocean (NIO) SST warming (during spring following the decay phase of El Niño) associated with El Niño is well captured by the model. Detailed analysis reveals that the surface heat flux variations mainly contribute to the El Niño forced TIO SST variations both in observations and model. However, spring warming is nearly stationary throughout the model integration period, indicating poor inter-decadal El Niño teleconnections. The observations on the other hand displayed maximum SST warming with strong seasonality from epoch to epoch. The model El Niño decay delayed by more than two seasons, results in persistent TIO/NIO SST warming through the following December unlike in the observations. The ocean wave adjustments and persistent westerly wind anomalies over the equatorial Pacific are responsible for late decay of El Niño in the model. Consistent late decay of El Niño, throughout the model integration period (low variance), is mainly responsible for the poor inter-decadal ENSO teleconnections to TIO/NIO. This study deciphers that the model needs to produce El Niño decay phase variability correctly to obtain decadal-modulations in ENSO teleconnection.

  9. 3-D Lagrangian-based investigations of the time-dependent cloud cavitating flows around a Clark-Y hydrofoil with special emphasis on shedding process analysis

    Science.gov (United States)

    Cheng, Huai-yu; Long, Xin-ping; Ji, Bin; Liu, Qi; Bai, Xiao-rui

    2018-02-01

    In the present paper, the unsteady cavitating flow around a 3-D Clark-Y hydrofoil is numerically investigated with the filter-based density correction model (FBDCM), a turbulence model and the Zwart-Gerber-Belamri (ZGB) cavitation model. A reasonable agreement is obtained between the numerical and experimental results. To study the complex flow structures more straightforwardly, a 3-D Lagrangian technology is developed, which can provide the particle tracks and the 3-D Lagrangian coherent structures (LCSs). Combined with the traditional methods based on the Eulerian viewpoint, this technology is used to analyze the attached cavity evolution and the re-entrant jet behavior in detail. At stage I, the collapse of the previous shedding cavity and the growth of a new attached cavity, the significant influence of the collapse both on the suction and pressure sides are captured quite well by the 3-D LCSs, which is underestimated by the traditional methods like the iso-surface of Q-criteria. As a kind of special LCSs, the arching LCSs are observed in the wake, induced by the counter-rotating vortexes. At stage II, with the development of the re-entrant jet, the influence of the cavitation on the pressure side is still not negligible. And with this 3-D Lagrangian technology, the tracks of the re-entrant jet are visualized clearly, moving from the trailing edge to the leading edge. Finally, at stage III, the re-entrant jet collides with the mainstream and finally induces the shedding. The cavitation evolution and the re-entrant jet movement in the whole cycle are well visualized with the 3-D Lagrangian technology. Moreover, the comparison between the LCSs obtained with 2-D and 3-D Lagrangian technologies indicates the advantages of the latter. It is demonstrated that the 3-D Lagrangian technology is a promising tool in the investigation of complex cavitating flows.

  10. The Evolution of the Population of the City of Zagreb with Special Emphasis on Immigration in the Period 1991−2001

    Directory of Open Access Journals (Sweden)

    Nada Antić

    2001-12-01

    Full Text Available The paper describes the evolution of Zagreb's population and its geographical distribution in the city during the last ten years. Emphasis is placed on the role of migration (involving essentially the settling in of new inhabitants and on the influence of the armed conflict in the 1990s. The author also outlines some predictions regarding future developments. The paper uses primarily the results of the last censuses, including those of the recent census of 2001, as well as statistical data on the current population, on displaced persons and refugees, information in the possession of the municipality, etc. As to migration, since the last census was lacking in regard to migration indicators and there is no population registry, vital-statistical methods were applied to obtain a net migration balance. In the past, especially after WWII, Zagreb experienced considerable demographical growth, owing to its attractiveness for migration flows from other regions in Croatia and in neighbouring Bosnia and Herzegovina. The natural component in the evolution of the population was equally positive, yet a tendency towards reduction appeared in the 1980s. The first part of the paper reviews the demographic expansion of Zagreb in the earlier period (1857−1991, which was accompanied by an extension of the city. The results of the last census (2001 indicate a notable slowing down of population growth in Zagreb (arriving at a growth rate of 0.39%, for although war-induced migrations in the period 1991−1995 did direct the majority of the refugees and displaced persons to Zagreb, this flow was not accompanied by permanent settlement. Most migrants originated from Bosnia and Herzegovina (mainly refugees, after which followed migrants from regions in Croatia. Studies also show that during the most recent period there was a clear increase of out-migration from Zagreb to the outer suburbs and of emigration abroad. The second part of the paper offers indicators on the

  11. Precocious Puberty or Premature Thelarche: Analysis of a Large Patient Series in a Single Tertiary Center with Special Emphasis on 6- to 8-Year-Old Girls

    Directory of Open Access Journals (Sweden)

    Tero Varimo

    2017-08-01

    Full Text Available IntroductionWe describe the etiology, MRI findings, and growth patterns in girls who had presented with signs of precocious puberty (PP, i.e., premature breast development or early menarche. Special attention was paid to the diagnostic findings in 6- to 8-year-olds.Materials and methodsWe reviewed the medical records of 149 girls (aged 0.7–10.3 years who had been evaluated for PP in the Helsinki University Hospital between 2001 and 2014.ResultsIn 6- to 8-year-old girls, PP was most frequently caused by idiopathic gonadotropin-releasing hormone (GnRH-dependent PP (60% and premature thelarche (PT; 39%. The former subgroup grew faster (8.7 ± 2.0 cm/year, n = 58 than the girls with PT (7.0 ± 1.1 cm/year, n = 32 (P < 0.001, and the best discrimination for GnRH-dependent PP was achieved with a growth velocity cut-off value of 7.0 cm/year (sensitivity 92% and specificity 58% [area under the curve 0.82, 95% confidence interval (CI 0.73–0.91, P < 0.001]. Among asymptomatic and previously healthy 6- to 8-year-old girls with GnRH-dependent PP, one (1.7%, 95% CI 0.3–9.7% had a pathological brain MRI finding requiring surgical intervention (craniopharyngioma. In girls younger than 3 years, the most frequent cause of breast development was PT, and, in 3- to 6-year-olds, GnRH-dependent PP.ConclusionIn 6- to 8-year-old girls, analysis of growth velocity is helpful in differentiating between PT and GnRH-dependent PP. Although the frequency of clinically relevant intracranial findings in previously healthy, asymptomatic 6- to 8-year-old girls was low, they can present without any signs or symptoms, which favors routine MRI imaging also in this age group.

  12. Characterization of Novel Di-, Tri-, and Tetranucleotide Microsatellite Primers Suitable for Genotyping Various Plant Pathogenic Fungi with Special Emphasis on Fusaria and Mycospherella graminicola

    Directory of Open Access Journals (Sweden)

    Joseph-Alexander Verreet

    2012-03-01

    Full Text Available The goals of this investigation were to identify and evaluate the use of polymorphic microsatellite marker (PMM analysis for molecular typing of seventeen plant pathogenic fungi. Primers for di-, tri-, and tetranucleotide loci were designed directly from the recently published genomic sequence of Mycospherlla graminicola and Fusarium graminearum. A total of 20 new microsatellite primers as easy-to-score markers were developed. Microsatellite primer PCR (MP-PCR yielded highly reproducible and complex genomic fingerprints, with several bands ranging in size from 200 to 3000 bp. Of the 20 primers tested, only (TAGG4, (TCC5 and (CA7T produced a high number of polymorphic bands from either F. graminearum or F. culmorum. (ATG5 led to successful amplifications in M. graminicola isolates collected from Germany. Percentage of polymorphic bands among Fusarium species ranged from 9 to 100%. Cluster analysis of banding patterns of the isolates corresponded well to the established species delineations based on morphology and other methods of phylogenetic analysis. The current research demonstrates that the newly designed microsatellite primers are reliable, sensitive and technically simple tools for assaying genetic variability in plant pathogenic fungi.

  13. A meta-analysis of work-family conflict and various outcomes with a special emphasis on cross-domain versus matching-domain relations.

    Science.gov (United States)

    Amstad, Fabienne T; Meier, Laurenz L; Fasel, Ursula; Elfering, Achim; Semmer, Norbert K

    2011-04-01

    A literature review of studies analyzing work-family conflict and its consequences was conducted, and 427 effect sizes were analyzed meta-analytically. Work-family conflict was analyzed bidirectionally in terms of work interference with family (WIF) and family interference with work (FIW). We assessed 3 categories of potential outcomes: work-related outcomes, family-related outcomes, and domain-unspecific outcomes. Results show that WIF and FIW are consistently related to all 3 types of outcomes. Both types of interrole conflict showed stronger relationships to same-domain outcomes than to cross-domain outcomes. Thus, WIF was more strongly associated with work-related than with family-related outcomes, and FIW was more strongly associated with family-related than with work-related outcomes. In moderator analyses, parenthood could not explain variability in effect sizes. However, time spent at work did moderate the relationships between WIF and family-related outcomes, as well as FIW and domain-unspecific outcomes.

  14. A Europe-wide system for assessing the quality of rivers using macroinvertebrates: the AQEM Project* and its importance for southern Europe (with special emphasis on Italy

    Directory of Open Access Journals (Sweden)

    Joanna L. KEMP

    2001-09-01

    Full Text Available The AQEM Project aims to develop a Europe-wide system for monitoring the ecological quality of rivers using macroinvertebrates, to satisfy the requirements of the EU Water Framework Directive. Three main types of anthropogenic perturbation are being investigated: morphological degradation, water (organic pollution and acidification (the last is not under investigation in Italy. The selection of reference and impaired study sites is discussed. Particular attention is paid to the problems encountered when defining reference conditions. The initial stages of the project highlighted the lack of a Europe-wide definition of river types. The future development of such a typology from the AQEM database is discussed. The standard AQEM data gathering methods are presented, from background information about sites to the microhabitat-based macroinvertebrate sampling method. The extended fieldwork methods used in Italy are described. These included the separate analysis of the invertebrate assemblages from each replicate, the recording of additional microhabitat variables for each replicate and the completion of large-scale survey techniques for each site (including RHS. The extended method was designed to enhance the important ecological information available from the dataset, particularly relevant in Italy where significant gaps exist in the taxonomic and ecological knowledge of many macroinvertebrate taxa. Preliminary and expected findings are presented, including examples of the range and habitat selection of two species of Ephemeroptera endemic to Italy, as well as data relating to the number of taxa found at a site with increasing numbers of microhabitat replicates taken. The importance of the AQEM Project not only for biomonitoring, but also for ecology, taxonomy and conservation, in Italy and for the south of Europe in general, is emphasised.

  15. Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica.

    Science.gov (United States)

    Chan, Kelvin; Shaw, Debbie; Simmonds, Monique S J; Leon, Christine J; Xu, Qihe; Lu, Aiping; Sutherland, Ian; Ignatova, Svetlana; Zhu, You-Ping; Verpoorte, Rob; Williamson, Elizabeth M; Duez, Pierre

    2012-04-10

    Studies on traditional Chinese medicine (TCM), like those of other systems of traditional medicine (TM), are very variable in their quality, content and focus, resulting in issues around their acceptability to the global scientific community. In an attempt to address these issues, an European Union funded FP7 consortium, composed of both Chinese and European scientists and named "Good practice in traditional Chinese medicine" (GP-TCM), has devised a series of guidelines and technical notes to facilitate good practice in collecting, assessing and publishing TCM literature as well as highlighting the scope of information that should be in future publications on TMs. This paper summarises these guidelines, together with what has been learned through GP-TCM collaborations, focusing on some common problems and proposing solutions. The recommendations also provide a template for the evaluation of other types of traditional medicine such as Ayurveda, Kampo and Unani. GP-TCM provided a means by which experts in different areas relating to TCM were able to collaborate in forming a literature review good practice panel which operated through e-mail exchanges, teleconferences and focused discussions at annual meetings. The panel involved coordinators and representatives of each GP-TCM work package (WP) with the latter managing the testing and refining of such guidelines within the context of their respective WPs and providing feedback. A Good Practice Handbook for Scientific Publications on TCM was drafted during the three years of the consortium, showing the value of such networks. A "deliverable - central questions - labour division" model had been established to guide the literature evaluation studies of each WP. The model investigated various scoring systems and their ability to provide consistent and reliable semi-quantitative assessments of the literature, notably in respect of the botanical ingredients involved and the scientific quality of the work described. This

  16. Which variables relate to the attitudes of teachers, parents and peers towards students with special educational needs in regular education?

    NARCIS (Netherlands)

    de Boer, Anke; Pijl, Sip Jan; Post, Wendy; Minnaert, Alexander

    2012-01-01

    While there is an increased interest in describing attitudes of teachers, parents and peers towards students with special educational needs in regular education, there is a lack of knowledge about various variables relating to the attitudes of these three groups. The aims of this study are: (1) to

  17. A Content Analysis of the Postgraduate Thesis Written on Special Education in Turkey Based on Various Variables (2009-2014)

    Science.gov (United States)

    Demirok, Mukaddes Sakalli; Besgul, Meyrem; Baglama, Basak

    2016-01-01

    The aim of this study was to examine postgraduate thesis studies conducted between the years of 2009 and 2014 in special education field in Turkey based on various variables and figure out how many of these thesis is related with hearing disability. A total number of 146 postgraduate thesis have been found in the thesis scanning center of Higher…

  18. Spatio-Temporal Variability of Summer Precipitation in Mexico under the Influence of the MJO, with Emphasis on the Bimodal Pattern

    Science.gov (United States)

    Perdigón, J.; Romero-Centeno, R.; Barrett, B.; Ordoñez-Perez, P.

    2017-12-01

    In many regions of Mexico, precipitation occurs in a very well defined annual cycle with peaks in May-June and September-October and a relative minimum in the middle of the rainy season known as the midsummer drought (MSD). The MJO is the most important mode of intraseasonal variability in the tropics, and, although some studies have shown its evident influence on summer precipitation in Mexico, its role in modulating the bimodal pattern of the summer precipitation cycle is still an open question. The spatio-temporal variability of summer precipitation in Mexico is analyzed through composite analysis according to the phases of the MJO, using the very high resolution CHIRPS precipitation data base and gridded data from the CFSR reanalysis to analyzing the MJO influence on the atmospheric circulation over Mexico and its adjacent basins. In general, during MJO phases 8-2 (4-6) rainfall is above-normal (below-normal), although, in some cases, the summer rainfall patterns during the same phase present considerable differences. The atmospheric circulation shows low (high) troposphere southwesterly (northeasterly) wind anomalies in southern Mexico under wetter conditions compared with climatological patterns, while the inverse pattern is observed under drier conditions. Composite anomalies of several variables also agreed well with those rainfall anomalies. Finally, a MJO complete cycle that reinforces (weakens) the bimodal pattern of summer rainfall in Mexico was found.

  19. 78 FR 63207 - Special Emphasis Panel; Meeting

    Science.gov (United States)

    2013-10-23

    ... Implementation of Patient Centered Outcomes Research (U18)''. Each SEP meeting will commence in open session... expertise. Each SEP meeting will commence in open session before closing to the public for the duration of... applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy...

  20. AN EXAMPLE FOR BURNOUT: SPECIAL EDUCATION EDUCATOR?S BURNOUT LEVEL AND SOME VARIABLES

    Directory of Open Access Journals (Sweden)

    Gunseli GIRGIN

    2005-08-01

    Full Text Available Teaching profession is a strategic occupation in that it conributes to educating the adults of the future. However,depending on some stress sources related with the occupation teachers have a special risk for menthal health.Depending on literature, negative life events,loss of energy and formation of some physical discomfort is defined as?burnout sendrom?. With the belief that this group of teachers were closer to the risk of burnout because of the responsibilities they carry in relation with the needs of the special education children the aim of the study was to investigate the burnout syndrome of special education teachers in relation with their sex, age, socio-economic status, perceived support from collegues, beliefs on status of their occupation, and appreciation from their administors. The sample of this study consists of 48 special education teachers teaching at different special education institutes at Izmir. Maslach Burnout Inventory-Teacher Form and Personal Information Survey were used for gathering the data. The analysis of the data demonstrated that sex is positively related with special education teachers emotional burnout and insensitiveness level. Men have higher scores in these subdimensions. Participants from middle socio-economic status are seen to have the lowest scores in all dimensions. Participants that perceive support from collegues are seen to have significantly lower scores on emotional burnout and insensitiveness dimensions. Special education teachers who think that the status of their occupation is low in society are seen to have higher scores in emotional burnout. Beliefs about appreciation from their administors are seen to be related with burnout level of special education teachers. Participants that believed that they were not appreciated by their administrators have significantly higher scores on emotional burnout and insensitiveness subdimensions. [TAF Prev Med Bull 2005; 4(4.000: 172-187

  1. Radiative forcing estimates of sulfate aerosol in coupled climate-chemistry models with emphasis on the role of the temporal variability

    Directory of Open Access Journals (Sweden)

    C. Déandreis

    2012-06-01

    Full Text Available This paper describes the impact on the sulfate aerosol radiative effects of coupling the radiative code of a global circulation model with a chemistry-aerosol module. With this coupling, temporal variations of sulfate aerosol concentrations influence the estimate of aerosol radiative impacts. Effects of this coupling have been assessed on net fluxes, radiative forcing and temperature for the direct and first indirect effects of sulfate.

    The direct effect respond almost linearly to rapid changes in concentrations whereas the first indirect effect shows a strong non-linearity. In particular, sulfate temporal variability causes a modification of the short wave net fluxes at the top of the atmosphere of +0.24 and +0.22 W m−2 for the present and preindustrial periods, respectively. This change is small compared to the value of the net flux at the top of the atmosphere (about 240 W m−2. The effect is more important in regions with low-level clouds and intermediate sulfate aerosol concentrations (from 0.1 to 0.8 μg (SO4 m−3 in our model.

    The computation of the aerosol direct radiative forcing is quite straightforward and the temporal variability has little effect on its mean value. In contrast, quantifying the first indirect radiative forcing requires tackling technical issues first. We show that the preindustrial sulfate concentrations have to be calculated with the same meteorological trajectory used for computing the present ones. If this condition is not satisfied, it introduces an error on the estimation of the first indirect radiative forcing. Solutions are proposed to assess radiative forcing properly. In the reference method, the coupling between chemistry and climate results in a global average increase of 8% in the first indirect radiative forcing. This change reaches 50% in the most sensitive regions. However, the reference method is not suited to run long climate

  2. An Applied Study of Implementation of the Advanced Decommissioning Costing Methodology for Intermediate Storage Facility for Spent Fuel in Studsvik, Sweden with special emphasis to the application of the Omega code

    Energy Technology Data Exchange (ETDEWEB)

    Kristofova, Kristina; Vasko, Marek; Daniska, Vladimir; Ondra, Frantisek; Bezak, Peter [DECOM Slovakia, spol. s.r.o., J. Bottu 2, SK-917 01 Trnava (Slovakia); Lindskog, Staffan [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    2007-01-15

    The presented study is focused on an analysis of decommissioning costs for the Intermediate Storage Facility for Spent Fuel (FA) facility in Studsvik prepared by SVAFO and a proposal of the advanced decommissioning costing methodology application. Therefore, this applied study concentrates particularly in the following areas: 1. Analysis of FA facility cost estimates prepared by SVAFO including description of FA facility in Studsvik, summarised input data, applied cost estimates methodology and summarised results from SVAFO study. 2. Discussion of results of the SVAFO analysis, proposals for enhanced cost estimating methodology and upgraded structure of inputs/outputs for decommissioning study for FA facility. 3. Review of costing methodologies with the special emphasis on the advanced costing methodology and cost calculation code OMEGA. 4. Discussion on implementation of the advanced costing methodology for FA facility in Studsvik together with: - identification of areas of implementation; - analyses of local decommissioning infrastructure; - adaptation of the data for the calculation database; - inventory database; and - implementation of the style of work with the computer code OMEGA.

  3. An Applied Study of Implementation of the Advanced Decommissioning Costing Methodology for Intermediate Storage Facility for Spent Fuel in Studsvik, Sweden with special emphasis to the application of the Omega code

    International Nuclear Information System (INIS)

    Kristofova, Kristina; Vasko, Marek; Daniska, Vladimir; Ondra, Frantisek; Bezak, Peter; Lindskog, Staffan

    2007-01-01

    The presented study is focused on an analysis of decommissioning costs for the Intermediate Storage Facility for Spent Fuel (FA) facility in Studsvik prepared by SVAFO and a proposal of the advanced decommissioning costing methodology application. Therefore, this applied study concentrates particularly in the following areas: 1. Analysis of FA facility cost estimates prepared by SVAFO including description of FA facility in Studsvik, summarised input data, applied cost estimates methodology and summarised results from SVAFO study. 2. Discussion of results of the SVAFO analysis, proposals for enhanced cost estimating methodology and upgraded structure of inputs/outputs for decommissioning study for FA facility. 3. Review of costing methodologies with the special emphasis on the advanced costing methodology and cost calculation code OMEGA. 4. Discussion on implementation of the advanced costing methodology for FA facility in Studsvik together with: - identification of areas of implementation; - analyses of local decommissioning infrastructure; - adaptation of the data for the calculation database; - inventory database; and - implementation of the style of work with the computer code OMEGA

  4. Variability in Demand for Special Education Teachers: Indicators, Explanations, and Impacts

    Science.gov (United States)

    Boe, Erling E.; deBettencourt, Laurie U.; Dewey, James; Rosenberg, Michael; Sindelar, Paul; Leko, Christopher

    2013-01-01

    After decades of growth, the number of special education teachers (SETs) has begun to decline. In 2009, U.S. schools employed 13% fewer SETs than in 2006. The number of annual new hires of SETs also dropped dramatically in some states. The onset of these declines predated the economic downturn of 2008 and resulted in part from a steady decline…

  5. 24. MPA-seminar: safety and reliability of plant technology with special emphasis on integrity and life management. Vol. 1. Papers 1-27; 24. MPA-Seminar: Sicherheit und Verfuegbarkeit in der Anlagentechnik mit dem Schwerpunkt Integritaet und Lebensdauermanagement. Bd. 1. Vortraege 1-27

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The first volume is dedicated to the safety and reliability of plant technology with special emphasis on the integrity and life management. The main topic in the volume is the contribution of nondestructive testing to the reactor safety from an international point of view. All 20 papers are separately analyzed for this database. (orig.)

  6. 24. MPA-seminar: safety and reliability of plant technology with special emphasis on integrity and life management. Vol. 2. Papers 28-63; 24. MPA-Seminar: Sicherheit und Verfuegbarkeit in der Anlagentechnik mit dem Schwerpunk Integritaet und Lebensdauermanagement. Bd. 2. Vortraege 28-63

    Energy Technology Data Exchange (ETDEWEB)

    1999-09-01

    The second volume is dedicated to the safety and reliability of plant technology with special emphasis on the integrity and life management. The following topics are discussed: 1. Integrity of vessels, pipes and components. 2. Fracture mechanics. 3. Measures for the extension of service life, and 4. Online Monitoring. All 30 contributions are separately analyzed for this database. (orig.)

  7. 23. MPA-Seminar: Safety and reliability of plant technology with special emphasis on behaviour of pressurized components and systems at increased loading. Vol. 2. Papers 27-50; 23. MPA-Seminar: Sicherheit und Verfuegbarkeit in der Anlagentechnik mit dem Schwerpunkt Verhalten von druckfuehrenden Komponenten und Systemen bei erhoehten Belastungen. Bd. 2. Vortraege 27-50

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    This book is dedicated to the components of nuclear and conventional power plants with special emphasis on the behaviour of pressurized components and systems. The following topics are discussed: 1. structure and safety analysis, 2. aging phenomena, 3. nondestructive testing, and 4. optimization of in-service inspection.

  8. Disproportionality in Special Education: Effects of Individual and School Variables on Disability Risk

    Science.gov (United States)

    Sullivan, Amanda L.; Bal, Aydin

    2013-01-01

    We examined the risk of disability identification associated with individual and school variables. The sample included 18,000 students in 39 schools of an urban K-12 school system. Descriptive analysis showed racial minority risk varied across 7 disability categories, with males and students from low-income backgrounds at highest risk in most…

  9. Determination of Self-Efficacy and Burnout State of Teachers Working in the Special Education Field in Terms of Different Variables

    Science.gov (United States)

    Nuri, Cahit; Demirok, Mukaddes Sakalli; Direktör, Cemaliye

    2017-01-01

    The aim of the study is to analyse the self-efficacy and burnout of special education teachers in terms of different variables such as gender, teachers' educational levels, teachers' daily working hours, and teachers' daily student numbers. 7 special education schools, affiliated to Turkish Republic of Northern Cyprus (TRNC) Ministry of Education…

  10. A content analysis of the postgraduate thesis written on special education in turkey based on various variables (2009-2014

    Directory of Open Access Journals (Sweden)

    Mukaddes Sakalli Demirok

    2016-06-01

    Full Text Available Abstract The aim of this study was to examine postgraduate thesis studies conducted between the years of 2009 and 2014 in special education field in Turkey based on various variables and figure out how many of these thesis is related with hearing disability. A total number of 146 postgraduate thesis have been found in the thesis scanning center of Higher Education Council (YOK of Turkey. 126 of these thesis were master thesis and 20 of them were doctorate thesis. Data of the research were analyzed in SPSS 20.0 program. According to the results, it was revealed that quantitative method is the most preferred method in postgraduate thesis and there is much more number of master thesis than doctorate thesis. According to the distribution of thesis based on disability group, thesis are mostly related with special education and there is least number of thesis related with dyslexia. Besides, there were not much number of studies conducted with individuals with disability. Recommendations and implications for further research are also provided based on the results.

  11. A comparative study of forestry in Finland, Norway, Sweden, and the United States, with special emphasis on policy measures for nonindustrial private forests in Norway and the United States.

    Science.gov (United States)

    Berit Hauger. Lindstad

    2002-01-01

    In recognition of the cultural, economic, and ecological importance of forestry in Finland, Norway, Sweden, and the United States, this paper compares forest resource data, ownership patterns, management issues, and the impact the forest sector has on the national economies of these four countries. There is particular emphasis on the analysis of policy measures that...

  12. Periodización de la formación de posgrado del médico en etapa de especialización en medicina general integral: dimensiones, variables y claves hermenéuticas Division into periods of the post degree training for the doctor in the specialization stage in General Comprehensive Medicine: volume, variables and hermeneutical keys

    Directory of Open Access Journals (Sweden)

    Nilia Victoria Escobar Yéndez

    Full Text Available Los profesionales que ejercen la medicina general integral, han tenido a su cargo la enorme responsabilidad de transformar la atávica concepción de la medicina prevaleciente durante varios lustros en un nuevo esquema con enfoque integral del individuo, su familia y la comunidad. Para este trabajo se identificaron 3 hitos de periodización e igual número de etapas; pero también dimensiones, variables y claves hermenéuticas del proceso de formación de posgrado del médico en etapa de especialización en medicina general integral, con especial énfasis en el desarrollo de competencias investigativas.The professionals who practice the General Comprehensive Medicine, have been in charge of the enormous responsibility of transforming the atavistic idea of the prevalent medicine during several years into a new outline with a comprehensive approach to the individual, his family and the community. For this work 3 landmarks for a division into periods and the same number of stages were identified, as well as, dimensions, variables and hermeneutical keys of the post degree training process for the doctor in specialization stage in General Comprehensive Medicine, with special emphasis in the development of investigative power.

  13. Special session on environment and energy, and repeated emphasis from early-'80s onwards, hybrid-drive targets for penetrating beams, that encompasses ultra high intensity lasers and/or particle beams

    International Nuclear Information System (INIS)

    Mark, J.W.

    1994-01-01

    In this special session, we discuss global climate change concerns, as well as cleanup of wastes and/or toxic materials, their relations to energy and other technologies. We especially bring together scientists to discuss available and/or developable technologies of amelioration or cleanup, for consideration of unusual uses of Lasers, Particle Beams and other plasma Phenomena. copyright American Institute of Physics 1994

  14. Excision repair cross-complementation group 1 (ERCC1) in platinum-based treatment of non-small cell lung cancer with special emphasis on carboplatin: a review of current literature

    DEFF Research Database (Denmark)

    Vilmar, A.; Sorensen, J.B.

    2009-01-01

    on carboplatin based on the current literature. Research on the development of a reliable methodology is warranted followed by validation in large, prospective, randomized trials as ERCC1 may possibly play an important role as tumour marker in tailored chemotherapy for NSCLC Udgivelsesdato: 2009/5......-complementation group 1 (ERCC1) has shown potential as a predictive marker in patients with NSCLC treated with cisplatin-based chemotherapy. Carboplatin has gained widespread use in the treatment of advanced NSCLC and its mechanisms of action are likely similar to that of cisplatin. MATERIALS AND METHODS: A literature...... review on ERCC1 was conducted as predictor in NSCLC patients receiving platinum-based treatment with emphasis on carboplatin. English language publications from January 1996 to February 2008 were eligible and data on methodology and outcome were recorded. RESULTS: Eight preclinical articles, 25 clinical...

  15. Analyzing the Anxiety States of Canditates Applying f or Special Talent Examination in the School of Physical Education and Sports in Terms of Several Variables

    Directory of Open Access Journals (Sweden)

    Yeşim SONGÜN

    2015-08-01

    Full Text Available In this study, anxiety states of candidates who were going to attend special talent examination in the School of Physical Education and Sports were analyzed in terms of various variables such as age, gender, residence and socio - economic level of the family , parents’ educational levels and professions, active sports status, the number of exams taken, and applied training methods. Within the scope of this study, 244 candidates who applied for the special talent examination held by the School of Physical Educa tion and Sports in Gümüşhane University in 2014 - 2015 academic year volunteered to participate. Regarding the data collection tool, a personal information form and State - Trait Anxiety Scale developed by Spielberger et. al were used. For the analysis of gath ered data, for paramedic variables, t test and test of One Way Anova were applied. For non paramedic variables, Kruskal Wallis test was applied. In order to determine the source of difference between the means Post Hoc Tukey test was applied. All the analy ses during the research process were carried out by SPSS 20.00 package program. As a result, it was found out that the only significant diff erence between the anxiety scores and the stated variables was in terms of candidates’ mothers’ occupation variable (F 239 = 2,507, p<.05 whereas no other significant difference was determined concerning other variables.

  16. Specialized science.

    Science.gov (United States)

    Casadevall, Arturo; Fang, Ferric C

    2014-04-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism.

  17. Effect of personal and situational variables on noise annoyance: With special reference to implications for en route noise

    Science.gov (United States)

    Fields, James M.

    1992-08-01

    Over 680 publications from 282 social surveys of residents' reactions to environmental noise have been examined to locate 495 published findings on 26 topics concerning non-noise explanations for residents' reactions to environmental noise. This report (1) tabulates the evidence on the 26 response topics, (2) identifies the 495 findings, and (3) discusses the implications for en route noise assessment. After controlling for noise level, over half of the social survey evidence indicates that noise annoyance is not strongly affected by any of the nine demographic variables examined (age, sex, social status, income, education, homeownership, type of dwelling, length of residence, or receipt of benefits from the noise source), but is positively associated with each of the five attitudinal variables examined (a fear of danger from the noise source, a sensitivity towards noise generally, the belief that the authorities can control the noise, the awareness of non-noise impacts of the source, and the belief that the noise source is not important).

  18. A purview of waste management evolution: special emphasis on USA.

    Science.gov (United States)

    Kollikkathara, Naushad; Feng, Huan; Stern, Eric

    2009-02-01

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste.

  19. Reaching the Unreached - Special Emphasis on the Communication ...

    African Journals Online (AJOL)

    This paper provides an overview of the existing communication component in the Expanded Program on Immunisation (EPI) training in Zambia and critically analyses the need for a humane touch in the communication process so as to reach the target audience effectively. Interpersonal Communication (IPC) in Zambia has ...

  20. A review of plague persistence with special emphasis on fleas

    Science.gov (United States)

    Wimsatt, Jeffrey; Biggins, Dean E.

    2009-01-01

    Sylvatic plague is highly prevalent during infrequent epizootics that ravage the landscape of western North America. During these periods, plague dissemination is very efficient. Epizootics end when rodent and flea populations are decimated and vectored transmission declines. A second phase (enzootic plague) ensues when plague is difficult to detect from fleas, hosts or the environment, and presents less of a threat to public health.

  1. Bird species of Mouau with special emphasis on foraging behavior ...

    African Journals Online (AJOL)

    Ten different bird species were peculiar to the Umudike environment and of these eight were regular thus closely observed and identified. The other two species were scarcely available and may be regarded as visiting birds. The eight species identified were either Passerine or Non-Passerine. The northern grey-headed ...

  2. Geology of Northwestern Switzerland - with special emphasis on Opalinus Clay

    International Nuclear Information System (INIS)

    Burkhard, M.

    2007-01-01

    This report describes the variations of the geological structures of Northwestern Switzerland during about the last 200 million years. This gives an explanation for the present partition of the different rock layers in the studied domain. The geology of Switzerland is dominated by the formation of the Alps. The Mont Terri geology is best explained within the framework of the tectonic Wilson cycle: assembly of Pangea in Late Paleozoic times culminating in the Variscan orogeny, collapse and decay of this earlier mountain chain, peneplanation and new rifting leading to the opening of the alpine Tethys Ocean during the Mesozoic, followed by plate convergence, subduction, collision and new mountain-building in the Neogene. The Mont Terri geology bears witness to the same suite of events as the Alps; tectonically speaking, Mont Terri is part of the Alps. Africa continues to push Apulia against the larger European plate and the question arises as to what the geological future has in store for our hills and mountains. Recent GPS (Global Positioning System) data Iead to believe that it will be just erosion and decay

  3. taxonomy and pylogeny of symphytum with special emphasis on ...

    African Journals Online (AJOL)

    hu

    2011-11-07

    Nov 7, 2011 ... research. In the phylogenetic tree, S. creticum Runemark and S. tuberosum L. were resolved as sisters. The objective of this research was to find out the phylogenetic relationships within Symphytum. Two gene regions: the internal transcribed spacer (ITS) and the intron and spacer of the chloroplast (trnL-F) ...

  4. Transport and sustainability - with special emphasis on grocery distribution

    Energy Technology Data Exchange (ETDEWEB)

    Joergensen, Kaj

    1999-12-31

    The reduction of the number of retail shops, in principle, provide for better planning opportunities regarding the distribution of commodities to the shops. But this, according to the study is more than offset by the longer distances the goods have to travel before reaching the shops. The report investigates the potentials for reduction of the energy demand and emission by means of technical improvements of vehicles. The assessments are based on fuel cycle considerations covering both the energy system (that is, the system providing the fuel to the vehicle) and the vehicle system (the system on board the vehicle transforming the fuel to useful work). In general, there are substantial potentials for improvements of the energy efficiency of the transportation means - and even greater potentials for CO{sub 2}-reductions. The reap the full potentials, it is probably necessary to break with the present technological development trend. (au) 274 refs.

  5. A purview of waste management evolution: Special emphasis on USA

    International Nuclear Information System (INIS)

    Kollikkathara, Naushad; Feng, Huan; Stern, Eric

    2009-01-01

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste

  6. Lupinus mutabilis in Ecuador with special emphasis on anthracnose resistance

    NARCIS (Netherlands)

    Falconi, C.

    2012-01-01

    The Tailoring Food Sciences to Endogenous Patterns of Local Food Supply for Future Nutrition (TELFUN) project aimed to support people to choose their own way of producing, processing, and consuming local foods that fit best in their local conditions. The central research question was: how do

  7. Emergency preparedness in Finland with special emphasis on internal contamination

    International Nuclear Information System (INIS)

    Rahola, Tua; Suomela, Matti

    1999-01-01

    Rapid development in the field of emergency preparedness has taken place during recent years. The very first measures in a possible emergency situation have been trained nationally and internationally. Less attention has been paid to measures in a later phase. To be able to react fast enough in an emergency situation it is essential to have well documented plans, written instructions and suitable measurement equipment ready for use. In the first phase of a nuclear accident iodine is of primary concern. The Finnish radiation protection authority - STUK has already some instruments calibrated for thyroidea measurements in field conditions outside the laboratory. In a Nordic project experts on internal contamination measurements will be trained to make rapid measurements with relatively simple instruments on large groups of people. The general public knows that it is possible to do direct measurements on people and will not accept prognoses based only on external radiation and foodstuff measurements. In the future it will be necessary to do also direct measurements on people for reassurance of the general public even if such measurement would not be necessary from a strict radiation protection point of view. (au)

  8. Suicide in Judaism with a Special Emphasis on Modern Israel

    Directory of Open Access Journals (Sweden)

    Eliezer Witztum

    2012-08-01

    Full Text Available Judaism considers the duty of preserving life as a paramount injunction. Specific injunctions against suicide appear in the Bible, Talmud, and thereafter. Nevertheless, Jewish tradition emphasizes that one should let himself be killed rather than violate cardinal rules of Jewish law. Mitigating circumstances are found for the six deaths by suicide mentioned in the Bible, for example to account for one's sins, or avoid shameful death. Heroic suicide is praised throughout the Jewish history, from the suicide of Samson and the collective suicide in Masada, to the collective readiness of Jews in Medieval times and during the Holocaust to kill themselves rather than succumb to their enemies. Suicide rates for Jews are lower than those of Protestants and Catholics. Similarly, suicide rates in Israel are lower in comparison to Europe and North America, although being higher than those in most Moslem Asian and North African countries. This low rate of suicide is found in Jewish Israelis of all ages, including in adolescents. Elevated suicidal risk may be found in specific sub-populations, including male Israeli soldiers, immigrants from the former USSR and Ethiopia, in particular adolescent immigrants from the former USSR, elderly Holocaust survivors, and young Israel-Arab women. The meaning of these findings is discussed according to different socio-cultural perspectives.

  9. Distributed data base systems with special emphasis toward POREL

    Science.gov (United States)

    Neuhold, E. J.

    1984-01-01

    In the last few years a number of research and advanced development projects have resulted in distributed data base management prototypes. POREL, developed at the University of Stuttgart, is a multiuser, distributed, relational system developed for wide and local area networks of minicomputers and advanced micros. The general objectives of such data base systems and the architecture of POREL are discussed. In addition a comparison of some of the the existing distributed DMBS is included to provide the reader with information about the current state of the art.

  10. EVALUATION OF LANDFILL POLLUTION WITH SPECIAL EMPHASIS ON HEAVY METALS

    Directory of Open Access Journals (Sweden)

    Magdalena Vaverková

    2014-04-01

    Full Text Available Monitoring leachate, groundwater and surface water aiming to determinate the concentration of heavy metals (Hg, Zn, Ni, Cr6+,Cd, Pb at the municipal solid waste landfill Štěpánovice took place in the years 2002–2010. The values of heavy metals concentration oscillated as follows: Zn (0.05 – 0.37 μg/dm3, Cr+6 (0.01 – 3.3 μg/dm3, Hg (0.0001 – 0.001 (μg/dm3, Ni (0.001 – 0.19 μg/dm3, Cd (0.001 – 0.007 μg/dm3 and Pb (0.002 – 0.176 μg/dm3. The measured data show that the concentrations of heavy metals met the limits provided by law. Under the current landfill operation mode, the results of measurements do not indicate any negative impact on the quality of surface water, groundwater or leachate water.

  11. Biodiesel production with special emphasis on lipase-catalyzed transesterification.

    Science.gov (United States)

    Bisen, Prakash S; Sanodiya, Bhagwan S; Thakur, Gulab S; Baghel, Rakesh K; Prasad, G B K S

    2010-08-01

    The production of biodiesel by transesterification employing acid or base catalyst has been industrially accepted for its high conversion and reaction rates. Downstream processing costs and environmental problems associated with biodiesel production and byproducts recovery have led to the search for alternative production methods. Recently, enzymatic transesterification involving lipases has attracted attention for biodiesel production as it produces high purity product and enables easy separation from the byproduct, glycerol. The use of immobilized lipases and immobilized whole cells may lower the overall cost, while presenting less downstream processing problems, to biodiesel production. The present review gives an overview on biodiesel production technology and analyzes the factors/methods of enzymatic approach reported in the literature and also suggests suitable method on the basis of evidence for industrial production of biodiesel.

  12. Transport and sustainability - with special emphasis on grocery distribution

    Energy Technology Data Exchange (ETDEWEB)

    Joergensen, Kaj

    1998-12-31

    The reduction of the number of retail shops, in principle, provide for better planning opportunities regarding the distribution of commodities to the shops. But this, according to the study is more than offset by the longer distances the goods have to travel before reaching the shops. The report investigates the potentials for reduction of the energy demand and emission by means of technical improvements of vehicles. The assessments are based on fuel cycle considerations covering both the energy system (that is, the system providing the fuel to the vehicle) and the vehicle system (the system on board the vehicle transforming the fuel to useful work). In general, there are substantial potentials for improvements of the energy efficiency of the transportation means - and even greater potentials for CO{sub 2}-reductions. The reap the full potentials, it is probably necessary to break with the present technological development trend. (au) 274 refs.

  13. Dynamics of mechanical systems with variable mass

    CERN Document Server

    Belyaev, Alexander

    2014-01-01

    The book presents up-to-date and unifying formulations for treating dynamics of different types of mechanical systems with variable mass. The starting point is overview of the continuum mechanics relations of balance and jump for open systems from which extended Lagrange and Hamiltonian formulations are derived. Corresponding approaches are stated at the level of analytical mechanics with emphasis on systems with a position-dependent mass and at the level of structural mechanics. Special emphasis is laid upon axially moving structures like belts and chains, and on pipes with an axial flow of fluid. Constitutive relations in the dynamics of systems with variable mass are studied with particular reference to modeling of multi-component mixtures. The dynamics of machines with a variable mass are treated in detail and conservation laws and the stability of motion will be analyzed. Novel finite element formulations for open systems in coupled fluid and structural dynamics are presented.

  14. Emphasis: an active management model

    International Nuclear Information System (INIS)

    Gray, L.M.

    1983-01-01

    The Institute of Nuclear Materials Management was founded and has grown on the basis of promoting professionalism in the nuclear industry. This paper is concerned with professional management of nuclear material. The paper introduces the reader to Emphasis, an active management model. The management model provides the framework to assist a manager in directing his available resources. Emphasis provides for establishing goals, identifying and selecting objectives, matching objectives to specific personnel, preparing and monitoring action plans, and evaluating results. The model stresses crisis prevention by systematically administering and controlling resources. A critical requirement for implementation of the model is the desire to manage, to be in charge of the situation. The nuclear industry does need managers - people who realize the sensitive nature of the industry, professionals who insist on improved performance

  15. Response rates and selection problems, with emphasis on mental health variables and DNA sampling, in large population-based, cross-sectional and longitudinal studies of adolescents in Norway

    Directory of Open Access Journals (Sweden)

    Lien Lars

    2010-10-01

    Full Text Available Abstract Background Selection bias is a threat to the internal validity of epidemiological studies. In light of a growing number of studies which aim to provide DNA, as well as a considerable number of invitees who declined to participate, we discuss response rates, predictors of lost to follow-up and failure to provide DNA, and the presence of possible selection bias, based on five samples of adolescents. Methods We included nearly 7,000 adolescents from two longitudinal studies of 18/19 year olds with two corresponding cross-sectional baseline studies at age 15/16 (10th graders, and one cross-sectional study of 13th graders (18/19 years old. DNA was sampled from the cheek mucosa of 18/19 year olds. Predictors of lost to follow-up and failure to provide DNA were studied by Poisson regression. Selection bias in the follow-up at age 18/19 was estimated through investigation of prevalence ratios (PRs between selected exposures (physical activity, smoking and outcome variables (general health, mental distress, externalizing problems measured at baseline. Results Out of 5,750 who participated at age 15/16, we lost 42% at follow-up at age 18/19. The percentage of participants who gave their consent to DNA provision was as high as the percentage that consented to a linkage of data with other health registers and surveys, approximately 90%. Significant predictors of lost to follow-up and failure to provide DNA samples in the present genetic epidemiological study were: male gender; non-western ethnicity; postal survey compared with school-based; low educational plans; low education and income of father; low perceived family economy; unmarried parents; poor self-reported health; externalized symptoms and smoking, with some differences in subgroups of ethnicity and gender. The association measures (PRs were quite similar among participants and all invitees, with some minor discrepancies in subgroups of non-western boys and girls. Conclusions Lost to

  16. Spatio-temporal variability of lightning and convective activity over South/South-East Asia with an emphasis during El Niño and La Niña

    Science.gov (United States)

    Saha, Upal; Siingh, Devendraa; Midya, S. K.; Singh, R. P.; Singh, A. K.; Kumar, S.

    2017-11-01

    The present analysis investigates the spatio-temporal variability of the convective parameters and associated lightning flash rates during the period 1997-2013 including the El Niño and La Niña episode. It reveals that north-western and north-eastern part along the foothills of Himalayas as well as Indo-China peninsular region and South China Sea are much convective prone zones over the South/South-East Asia. The terrain/orography of the Himalayan range, the influence of cross-equatorial low-level jet and large-scale circulation during pre-monsoon and active phase of monsoon, the western Pacific Warm Pool with increased sea surface temperature as well as the solar-heating-originated local instability instigate the convective anomaly to propagate over the north-western and north eastern Indian sub-continent along with the Indo-China peninsula and South China Sea respectively. The land surfaces of the Indian sub-continent and the sea surface of South China Sea possesses significant correlation with lightning flash rates and convective parameters whereas the sea surface surrounding Indian sub-continent do not show such good correlations among them. Although, the occurrence of convective activities during the El Niño (La Niña) gets reduced (increased), the occurrence of lightning flashes gets enhanced (diminished) during this period which may be the direct consequence of warming atmosphere in relation to changing patterns of regional climate. Fig. S2 Spatial trend distribution per year of (a) LFR, (b) CAPE, (c) SCP, (d) LI, (e) CINE and (f) AT anomaly over South/South-East Asia during January-December for the years 1997-2013 (Trend is significant at 95% confidence level). Fig. S3 Correlation maps of LFR with (a) CAPE, (b) SCP, (c) CINE and (d) LI over South/South-East Asia during January-December for the years 1997-2013. Fig. S4 Synoptic wind direction patterns during (a)-(b) El Niño (May 2002 - February 2003) conditions and (c)-(d) La Niña (July 1998 - March

  17. Response rates and selection problems, with emphasis on mental health variables and DNA sampling, in large population-based, cross-sectional and longitudinal studies of adolescents in Norway.

    Science.gov (United States)

    Bjertness, Espen; Sagatun, Ase; Green, Kristian; Lien, Lars; Søgaard, Anne Johanne; Selmer, Randi

    2010-10-12

    Selection bias is a threat to the internal validity of epidemiological studies. In light of a growing number of studies which aim to provide DNA, as well as a considerable number of invitees who declined to participate, we discuss response rates, predictors of lost to follow-up and failure to provide DNA, and the presence of possible selection bias, based on five samples of adolescents. We included nearly 7,000 adolescents from two longitudinal studies of 18/19 year olds with two corresponding cross-sectional baseline studies at age 15/16 (10th graders), and one cross-sectional study of 13th graders (18/19 years old). DNA was sampled from the cheek mucosa of 18/19 year olds. Predictors of lost to follow-up and failure to provide DNA were studied by Poisson regression. Selection bias in the follow-up at age 18/19 was estimated through investigation of prevalence ratios (PRs) between selected exposures (physical activity, smoking) and outcome variables (general health, mental distress, externalizing problems) measured at baseline. Out of 5,750 who participated at age 15/16, we lost 42% at follow-up at age 18/19. The percentage of participants who gave their consent to DNA provision was as high as the percentage that consented to a linkage of data with other health registers and surveys, approximately 90%. Significant predictors of lost to follow-up and failure to provide DNA samples in the present genetic epidemiological study were: male gender; non-western ethnicity; postal survey compared with school-based; low educational plans; low education and income of father; low perceived family economy; unmarried parents; poor self-reported health; externalized symptoms and smoking, with some differences in subgroups of ethnicity and gender. The association measures (PRs) were quite similar among participants and all invitees, with some minor discrepancies in subgroups of non-western boys and girls. Lost to follow-up had marginal impact on the estimated prevalence ratios

  18. Developments in special geometry

    International Nuclear Information System (INIS)

    Mohaupt, Thomas; Vaughan, Owen

    2012-01-01

    We review the special geometry of N = 2 supersymmetric vector and hypermultiplets with emphasis on recent developments and applications. A new formulation of the local c-map based on the Hesse potential and special real coordinates is presented. Other recent developments include the Euclidean version of special geometry, and generalizations of special geometry to non-supersymmetric theories. As applications we discuss the proof that the local r-map and c-map preserve geodesic completeness, and the construction of four- and five-dimensional static solutions through dimensional reduction over time. The shared features of the real, complex and quaternionic version of special geometry are stressed throughout.

  19. Free energy of activation. Definition, properties, and dependent variables with special reference to linear free energy relations

    International Nuclear Information System (INIS)

    Levine, R.D.

    1979-01-01

    The reaction rate constant is expressed as Z exp(-G/sub a//RT). Z is the binary collision frequency. G/sub a/, the free energy of activation, is shown to be the difference between the free energy of the reactive reactants and the free energy of all reactants. The results are derived from both a statistical mechanical and a collision theoretic point of view. While the later is more suitable for an ab-initio computation of the reaction rate, it is the former that lends itself to the search of systematics and of correlations and to compaction of data. Different thermodynamic-like routes to the characterization of G/sub a/ are thus explored. The two most promising ones appear to be the use of thermodynamic type cycles and the changes of dependent variables using the Legendre transform technique. The dependence of G/sub a/ on ΔG 0 , the standard free energy change in the reaction, is examined from the later point of view. It is shown that one can rigorously express this dependence as G/sub a/ = αΔG 0 + G/sub a/ 0 M(α). Here α is the Bronsted slope, α = -par. delta ln k(T)/par. delta(ΔG 0 /RT), G/sub a/ 0 is independent of ΔG 0 and M(α), the Legendre transform of G/sub a/, is a function only of α. For small changes in ΔG 0 , the general result reduces to the familiar ''linear'' free energy relation delta G/sub a/ = α delta ΔG 0 . It is concluded from general considerations that M(α) is a symmetric, convex function of α and hence that α is a monotonically increasing function of ΔG 0 . Experimental data appear to conform well to the form α = 1/[1 + exp(-ΔG 0 /G/sub s/ 0 )]. A simple interpretation of the ΔG 0 dependence of G/sub a/, based on an interpolation of the free energy from that of the reagents to that of the products, is offered. 4 figures, 69 references

  20. Computed tomography-based lung nodule volumetry - do optimized reconstructions of routine protocols achieve similar accuracy, reproducibility and interobserver variability to that of special volumetry protocols?

    International Nuclear Information System (INIS)

    Bolte, H.; Riedel, C.; Knoess, N.; Hoffmann, B.; Heller, M.; Biederer, J.; Freitag, S.

    2007-01-01

    Purpose: The aim of this in vitro and ex vivo CT study was to investigate whether the use of a routine thorax protocol (RTP) with optimized reconstruction parameters can provide comparable accuracy, reproducibility and interobserver variability of volumetric analyses to that of a special volumetry protocol (SVP). Materials and Methods: To assess accuracy, 3 polyurethane (PU) spheres (35 HU; diameters: 4, 6 and 10 mm) were examined with a recommended SVP using a multislice CT (collimation 16 x 0.75 mm, pitch 1.25, 20 mAs, slice thickness 1 mm, increment 0.7 mm, medium kernel) and an optimized RTP (collimation 16 x 1.5 mm, pitch 1.25, 100 mAs, reconstructed slice thickness 2 mm, increment 0.4 mm, sharp kernel). For the assessment of intrascan and interscan reproducibility and interobserver variability, 20 artificial small pulmonary nodules were placed in a dedicated ex vivo chest phantom and examined with identical scan protocols. The artificial lesions consisted of a fat-wax-Lipiodol registered mixture. Phantoms and ex vivo lesions were examined afterwards using commercial volumetry software. To describe accuracy the relative deviations from the true volumes of the PU phantoms were calculated. For intrascan and interscan reproducibility and interobserver variability, the 95 % normal range (95 % NR) of relative deviations between two measurements was calculated. Results: For the SVP the achieved relative deviations for the 4, 6 and 10 mm PU phantoms were - 14.3 %, - 12.7 % and - 6.8 % and were 4.5 %, - 0.6 % and - 2.6 %, respectively, for the optimized RTP. SVP showed a 95 % NR of 0 - 1.5 % for intrascan and a 95 % NR of - 10.8 - 2.9 % for interscan reproducibility. The 95 % NR for interobserver variability was - 4.3 - 3.3 %. The optimized RTP achieved a 95 % NR of - 3.1 - 4.3 % for intrascan reproducibility and a 95 % NR of - 7.0 - 3.5 % for interscan reproducibility. The 95 % NR for interobserver variability was - 0.4 - 6.8 %. (orig.)

  1. Spatial variability of physical properties of tropical soil

    International Nuclear Information System (INIS)

    Reichardt, K.; Libardi, P.L.; Queiroz, S.V.; Grohmann, F.

    1976-04-01

    A basic study with objectives of improving the use of soil and water resources under a particular condition and of developing means for controlling the dynamics of soil-water movement are presented. Special emphasis is given to the variability in space of geometric soil properties such as bulk density, particle density and texture in order to make it possible to define representative means which ideed will be usable to describe the movement of water and of salt in the entire field

  2. Natural Variability of Mexican Forest Fires

    Science.gov (United States)

    Velasco-Herrera, Graciela; Velasco Herrera, Victor Manuel; Kemper-Valverdea, N.

    The purpose of this paper was 1) to present a new algorithm for analyzing the forest fires, 2) to discuss the present understanding of the natural variability at different scales with special emphasis on Mexico conditions since 1972, 3) to analyze the internal and external factors affecting forest fires for example ENSO and Total Solar Irradiance, and 4) to discuss the implications of this knowledge, on research and on restoration and management methods, which purpose is to enhance forest biodiversity conservation. 5) We present an estimate of the Mexican forest fires for the next decade. These results may be useful to minimize human and economic losses.

  3. Developing Adaptive Proficiency in Special Forces Officers

    National Research Council Canada - National Science Library

    White, Susan S; Mueller-Hanson, Rose A; Dorsey, David W; Pulakos, Elaine D; Wisecarver, Michelle M; Deagle, Edwin A., III; Mendini, Kip G

    2005-01-01

    Adaptive proficiency is critical for operating in the dynamic Special Forces (SF) mission environment and a recent focus on this requirement has resulted in a greater emphasis on adaptability in current training for SF...

  4. Program specialization

    CERN Document Server

    Marlet, Renaud

    2013-01-01

    This book presents the principles and techniques of program specialization - a general method to make programs faster (and possibly smaller) when some inputs can be known in advance. As an illustration, it describes the architecture of Tempo, an offline program specializer for C that can also specialize code at runtime, and provides figures for concrete applications in various domains. Technical details address issues related to program analysis precision, value reification, incomplete program specialization, strategies to exploit specialized program, incremental specialization, and data speci

  5. Project International Emphasis Interim Report, July 1991.

    Science.gov (United States)

    Blois, Beverly, Ed.; Williams, Barbara

    Project International Emphasis (PIE), a curriculum development effort involving all 24 colleges in the Virginia Community College System (VCCS), focuses on the infusion of globally oriented components across the academic curriculum and in related career development programs. Activities undertaken during the project's first year included an annual…

  6. Specialization Patterns

    DEFF Research Database (Denmark)

    Schultz, Ulrik Pagh; Lawall, Julia Laetitia; Consel, Charles

    2000-01-01

    Design patterns offer many advantages for software development, but can introduce inefficiency into the final program. Program specialization can eliminate such overheads, but is most effective when targeted by the user to specific bottlenecks. Consequently, we propose that these concepts...... are complementary. Program specialization can optimize programs written using design patterns, and design patterns provide information about the program structure that can guide specialization. Concretely, we propose specialization patterns, which describe how to apply program specialization to optimize uses...... of design patterns. In this paper, we analyze the specialization opportunities provided by specific uses of design patterns. Based on the analysis of each design pattern, we define the associated specialization pattern. These specialization opportunities can be declared using the specialization classes...

  7. The Relationship between El nino Southern Oscillation (ENSO) Phenomenon and Seasonal Precipitation Variability in Eastern Kenya with Special Reference to Katumani: Its Implication to Crop Production

    International Nuclear Information System (INIS)

    Kitheka, S.K

    1999-01-01

    Climatic variability has been defined as a major limitation to agricultural production in semi arid Kenya. The major difficulty to both farmers and research community, has been the inability to to predict seasonal rainfall prior to the season onset. Although several researches have attempted and made advances in predicting rainfall amount, solutions to the problem have not been achieved. This study has examined and related rainfall at Katumani with the El Nino-Southern Oscillation (ENSO) phenomenon. Rainfall variations during different phases of ENSO were established. Some advances in the early prediction of March-May and October -January rains for, both, the warm and cold phases of ENSO have been made. Crop production is closely related to the rainfall and therefore a need for revision of agronomic recommendation to tie them with rainfall variation

  8. A cost-constrained model of strategic service quality emphasis in nursing homes.

    Science.gov (United States)

    Davis, M A; Provan, K G

    1996-02-01

    This study employed structural equation modeling to test the relationship between three aspects of the environmental context of nursing homes; Medicaid dependence, ownership status, and market demand, and two basic strategic orientations: low cost and differentiation based on service quality emphasis. Hypotheses were proposed and tested against data collected from a sample of nursing homes operating in a single state. Because of the overwhelming importance of cost control in the nursing home industry, a cost constrained strategy perspective was supported. Specifically, while the three contextual variables had no direct effect on service quality emphasis, the entire model was supported when cost control orientation was introduced as a mediating variable.

  9. Gradient waveform pre-emphasis based on the gradient system transfer function.

    Science.gov (United States)

    Stich, Manuel; Wech, Tobias; Slawig, Anne; Ringler, Ralf; Dewdney, Andrew; Greiser, Andreas; Ruyters, Gudrun; Bley, Thorsten A; Köstler, Herbert

    2018-02-25

    The gradient system transfer function (GSTF) has been used to describe the distorted k-space trajectory for image reconstruction. The purpose of this work was to use the GSTF to determine the pre-emphasis for an undistorted gradient output and intended k-space trajectory. The GSTF of the MR system was determined using only standard MR hardware without special equipment such as field probes or a field camera. The GSTF was used for trajectory prediction in image reconstruction and for a gradient waveform pre-emphasis. As test sequences, a gradient-echo sequence with phase-encoding gradient modulation and a gradient-echo sequence with a spiral read-out trajectory were implemented and subsequently applied on a structural phantom and in vivo head measurements. Image artifacts were successfully suppressed by applying the GSTF-based pre-emphasis. Equivalent results are achieved with images acquired using GSTF-based post-correction of the trajectory as a part of image reconstruction. In contrast, the pre-emphasis approach allows reconstruction using the initially intended trajectory. The artifact suppression shown for two sequences demonstrates that the GSTF can serve for a novel pre-emphasis. A pre-emphasis based on the GSTF information can be applied to any arbitrary sequence type. © 2018 International Society for Magnetic Resonance in Medicine.

  10. Energy economics basics - Emphasis programme 2004 - 2007

    International Nuclear Information System (INIS)

    Gutzwiller, L.

    2005-01-01

    This report from the Swiss Federal Office of Energy (SFOE) examines the work done within the framework of the interdisciplinary energy economics programme on scenarios and instruments for energy policy-making and economics, as well as on social and environmental aspects. The report reviews the emphasis and goals of the next phase of the programme for the period 2004 - 2007. A research road map is discussed that is to identify promising technologies that will provide a substantial contribution to meeting the goal of creating the so-called '2000-Watt Society'. The road map is to also help identify technologies that provide socio-economic advantages and identify bottlenecks and restraints on the propagation of energy-efficient technologies in the building and transport areas

  11. Specialization Patterns

    OpenAIRE

    Schultz , Ulrik Pagh; Lawall , Julia ,; Consel , Charles

    1999-01-01

    Design patterns offer numerous advantages for software development, but can introduce inefficiency into the finished program. Program specialization can eliminate such overheads, but is most effective when targeted by the user to specific bottlenecks. Consequently, we propose to consider program specialization and design patterns as complementary concepts. On the one hand, program specialization can optimize object-oriented programs written using design patterns. On the other hand, design pat...

  12. EL PLAN DE ESTUDIOS DE LA CARRERA DE EDUCACIÓN ESPECIAL CON ÉNFASIS EN INTEGRACIÓN: UNA MIRADA DESDE LOS EGRESADOS (THE CURRICULUM OF THE SCHOOL OF SPECIAL EDUCATION WITH EMPHASIS ON INTEGRATION: A VIEW FROM THE GRADUATES

    Directory of Open Access Journals (Sweden)

    Hernández Segura, Ana María

    2012-05-01

    Full Text Available Resumen: El objetivo principal del artículo es presentar la valoración que hacen los egresados de la carrera de Educación Especial acerca del Plan de Estudios, para establecer relaciones con planteamientos de este documento y otras fuentes que se enmarcan en la fundamentación misma del Plan. Uno de los actores e informantes claves de estos procesos es un grupo de egresados de la carrera, quienes en este caso particular hacen una valoración de su proceso de formación docente, tomando en consideración aspectos tales como: desempeño laboral y habilidades desarrolladas, valores y actitudes, formación teórica-práctica recibida, así como contenidos adquiridos y desempeño profesional, todos aspectos contemplados en el Plan de Estudios de la Carrera. Participó un total de 31 egresados, graduados del periodo 2006-2009 y se utilizó un cuestionario que consta de 55 ítems. Las principales conclusiones del estudio evidencian que los egresados deben participar en espacios de consulta, los cuales les permitan fortalecer sus procesos reflexivos. En este sentido, los egresados valoran que la atención de poblaciones diversas, la actitud de disposición y la sensibilidad ante las diferencias que poseen las personas con necesidades educativas especiales son las tres habilidades desarrolladas durante su proceso de formación y que adquieren mayor trascendencia en el quehacer de su profesión. Desde la perspectiva de los egresados, la formación en valores es una de las fortalezas que tiene el Plan de Estudios de la carrera, lo cual permite asegurar que la dimensión del ser persona es de vital importancia para el desarrollo de la profesión docente.Abstract: The aim of the paper is to present the valuation made by graduates of the race on the Special Education Curriculum, to establish relationships with approaches of this document and other sources that fall under the same rationale of the Plan. One of the stakeholders and key informants from these

  13. Special Weapons

    Data.gov (United States)

    Federal Laboratory Consortium — Supporting Navy special weapons, the division provides an array of engineering services, technical publication support services, logistics support services, safety...

  14. Virtues and Well-Being of Korean Special Education Teachers

    Science.gov (United States)

    Kim, So-Young; Lim, Young-Jin

    2016-01-01

    Although much emphasis has been paid to stress and burnout among special education teachers, little attention has been paid to their well-being. This study aimed to examine relations between virtues and well-being among Korean special education teachers. Virtues and well-being of 115 Korean special education teachers were assessed using the…

  15. Internal and external North Atlantic Sector variability in the Kiel climate model

    Energy Technology Data Exchange (ETDEWEB)

    Latif, Mojib; Park, Wonsun; Ding, Hui; Keenlyside, Noel S. [Leibniz-Inst. fuer Meereswissenschaften, Kiel (Germany)

    2009-08-15

    The internal and external North Atlantic Sector variability is investigated by means of a multimillennial control run and forced experiments with the Kiel Climate Model (KCM). The internal variability is studied by analyzing the control run. The externally forced variability is investigated in a run with periodic millennial solar forcing and in greenhouse warming experiments with enhanced carbon dioxide concentrations. The surface air temperature (SAT) averaged over the Northern Hemisphere simulated in the control run displays enhanced variability relative to the red background at decadal, centennial, and millennial timescales. Special emphasis is given to the variability of the Meridional Overturning Circulation (MOC). The MOC plays an important role in the generation of internal climate modes. Furthermore, the MOC provides a strong negative feedback on the Northern Hemisphere SAT in both the solar and greenhouse warming experiments, thereby moderating the direct effects of the external forcing in the North Atlantic. The implications of the results for decadal predictability are discussed. (orig.)

  16. Special geometry

    International Nuclear Information System (INIS)

    Strominger, A.

    1990-01-01

    A special manifold is an allowed target manifold for the vector multiplets of D=4, N=2 supergravity. These manifolds are of interest for string theory because the moduli spaces of Calabi-Yau threefolds and c=9, (2,2) conformal field theories are special. Previous work has given a local, coordinate-dependent characterization of special geometry. A global description of special geometries is given herein, and their properties are studied. A special manifold M of complex dimension n is characterized by the existence of a holomorphic Sp(2n+2,R)xGL(1,C) vector bundle over M with a nowhere-vanishing holomorphic section Ω. The Kaehler potential on M is the logarithm of the Sp(2n+2,R) invariant norm of Ω. (orig.)

  17. Specialized languages

    DEFF Research Database (Denmark)

    Mousten, Birthe; Laursen, Anne Lise

    2016-01-01

    Across different fields of research, one feature is often overlooked: the use of language for specialized purposes (LSP) as a cross-discipline. Mastering cross-disciplinarity is the precondition for communicating detailed results within any field. Researchers in specialized languages work cross...... science fields communicate their findings. With this article, we want to create awareness of the work in this special area of language studies and of the inherent cross-disciplinarity that makes LSP special compared to common-core language. An acknowledgement of the importance of this field both in terms...... of more empirical studies and in terms of a greater application of the results would give language specialists in trade and industry a solid and updated basis for communication and language use....

  18. Spatial and temporal ecological variability in the northern Gulf of Alaska: What have we learned since the Exxon Valdez oil spill?

    Science.gov (United States)

    Aderhold, Donna G. R.; Lindeberg, Mandy R.; Holderied, Kris; Pegau, W. Scott

    2018-01-01

    This special issue examines oceanographic and biological variability in the northern Gulf of Alaska region with an emphasis on recent monitoring efforts of the Gulf Watch Alaska (GWA) and Herring Research and Monitoring (HRM) programs funded by the Exxon Valdez Oil Spill Trustee Council (EVOSTC). These programs are designed to improve our understanding of how changing environmental conditions affect Gulf of Alaska ecosystems and the long-term status of resources injured by the Exxon Valdez oil spill.

  19. U.S. Special Forces: culture warriors

    OpenAIRE

    Hill, Joshua L.

    2014-01-01

    Approved for public release; distribution is unlimited U.S. Army Special Forces (SF) are consistently called upon to work by, with, and through indigenous forces to conduct special warfare. Current SF doctrine reflects an increasing desire for SF operators to be culturally proficient in order to work closely with locals, advise foreign militaries, and build relationships with host-nation counterparts. Despite the doctrinal emphasis on cultural proficiency, SF doctrine offers little concret...

  20. An Introduction to the Special Volume on

    Directory of Open Access Journals (Sweden)

    Micah Altman

    2011-08-01

    Full Text Available This special volume of the Journal of Statistical Software on political methodology includes 14 papers, with wide-ranging software contributions of political scientists to their own field, and more generally to statistical data analysis in the the social sciences and beyond. Special emphasis is given to software that is written in or can cooperate with the R system for statistical computing.

  1. Special relativity

    International Nuclear Information System (INIS)

    Taylor, J.G.

    1975-01-01

    It is stated that the early chapters review special relativity from an elementary mathematical viewpoint, and include discussion of recent experiments which set out to test Einstein's predictions. The theory of relativity is then reformulated in more sophisticated mathematical language to show its relation to electro-magnetism, and to lay the foundation for more general viewpoints. The final chapter discusses in simple terms where activity in the field is currently centred, and where future interest lies. Chapter headings include: the constant speed of light; measuring time and distance; the Lorentz transformation (relativity of simultaneity, space-time and causality); relativistic kinematics (including - the Dopper effect); relativistic dynamics (including - nuclear binding energy, particle creation, electrodynamics); the structure of special relativity (including - the Lorentz group, the rotation group, elementary particle scattering); extensions of special relativity. (U.K.)

  2. Pork quality with special emphasis on colour and its changes during storage

    Directory of Open Access Journals (Sweden)

    Maria Bocian

    2018-03-01

    Full Text Available The aim of the study was to evaluate the quality of pork meat, including its colour after 24, 48, and 72 hours from the slaughter and its changes during storage. The meat was obtained from 52 crossbreed porkers F1 (Polish Large White x Polish Landrace, gilts and hogs in equal amounts. The assessment of the quality of the meat was performed in 48 hours after slaughter on the samples of the longissimus lumborum muscle. The meat was analysed in respect to its acidity (pH45 and pH48h, technological properties, and the level of the muscle colours. The sensory evaluation of the meat was conducted in terms of the intensity of colour, marbling, and firmness. The chemical composition of the meat and its tenderness was also evaluated. The colour of meat was measured by the use of the Minolta CR-300 apparatus in CIE L*a*b* system (L* - lightness, a* - participation of redness, b* - participation of yellowness, where the saturation of colour C* was calculated as well as the hue angle ho after 24, 48, and 72 hours from the slaughter. The changes (∆ of colour parameters after 24 h and 48 h of storage were calculated. Results demonstrated that the examined pork had the proper technological properties, it was tender (41.93 N/cm, and low in collagen (0.89%. During the storage of meat after 24, 48, and 72 hours from the slaughter, many significant changes appeared in the parameters of meat colour that is in L*, a*, b*, in saturation with C* and in the hue h° (P<0.01. The values of colour L* were changing into lighter (P<0.01, whereas the participation of colour red a*, yellow b* and the saturation of colour C* and its hue ho showed an increasing trend during storage (P<0.01. It was noticed that there are significant correlation coefficients between the colour parameters L*, a*, b*, its saturation C*, and hue ho, and the technological quality characteristics, the sensory intensity of colour, the content of muscle pigments at 24, 48 and 72 h after slaughter (P<0.01; P<0.05.

  3. The disposal of radioactive wastes in Brazil with special emphasis on rocks

    International Nuclear Information System (INIS)

    Enokihara, Cyro Teiti

    1983-01-01

    The disposal of radioactive wastes in geological formations seems to be the most appropriate solution for the nuclear waste problem. The disposal sites must provide the maximum safety for the radionuclides during its decay period. The study presents a general analysis of three types rocks: salt, granite and basalt. In our analysis we have dealt with the following aspects: geology, tectonics, seismicity, hydrogeology , mineral resources, geomorphology, population and access. The studied regions were: Sergipe-Alagoas and Reconcavo Basins, Northeastern and Southeastern Folded Regions and Parana Basin. Our study contains the macro-analysis needed for the selection of a safe site for radioactive waste disposal. We believe this work will be useful as a first step for further micro-analysis of selected sites. (author)

  4. Oral melanin pigmentation in 467 Thai and Malaysian people with special emphasis on smoker's melanosis.

    Science.gov (United States)

    Hedin, C A; Axéll, T

    1991-01-01

    At the faculties of dentistry in Chiang Mai, Thailand (CM), and Kuala Lumpur, Malaysia (KL), 234 and 233 consecutive out-patients were interviewed concerning tobacco and chewing habits and examined for the presence of oral melanin pigmentation. Tobacco was regularly used by 32% and 28% of the studied populations in CM and KL. Cigarette smoking was the predominant habit, but the chewing of betel and tea leaves (miang) and the smoking of banana leaf cigars (khi yo) was also registered. The genetically acquired pigmentation dominated. Although nearly all non-tobacco users in the Malay and Indian populations had oral melanin pigmentation, it was found that tobacco smokers had significantly more oral surfaces pigmented than non-tobacco users. Among Thais, the percentage of pigmented individuals was significantly higher among tobacco smokers. It was concluded that tobacco smoking stimulates oral melanocytes to a higher melanin production also in dark-skinned ethnic groups.

  5. Cryptic etiopathological conditions of equine nervous system with special emphasis on viral diseases

    Directory of Open Access Journals (Sweden)

    Rakesh Kumar

    2017-12-01

    Full Text Available The importance of horse (Equus caballus to equine practitioners and researchers cannot be ignored. An unevenly distributed population of equids harbors numerous diseases, which can affect horses of any age and breed. Among these, the affections of nervous system are potent reason for death and euthanasia in equids. Many episodes associated with the emergence of equine encephalitic conditions have also pose a threat to human population as well, which signifies their pathogenic zoonotic potential. Intensification of most of the arboviruses is associated with sophisticated interaction between vectors and hosts, which supports their transmission. The alphaviruses, bunyaviruses, and flaviviruses are the major implicated groups of viruses involved with equines/humans epizootic/epidemic. In recent years, many outbreaks of deadly zoonotic diseases such as Nipah virus, Hendra virus, and Japanese encephalitis in many parts of the globe addresses their alarming significance. The equine encephalitic viruses differ in their global distribution, transmission and main vector species involved, as discussed in this article. The current review summarizes the status, pathogenesis, pathology, and impact of equine neuro-invasive conditions of viral origin. A greater understanding of these aspects might be able to provide development of advances in neuro-protective strategies in equine population.

  6. Viral Diseases of Public Health Importance in India: Current Priorities with Special Emphasis on Prevention

    Directory of Open Access Journals (Sweden)

    Mageshbabu Ramamurthy

    2017-10-01

    Full Text Available India faces problems with both communicable and non communicable diseases. The major non communicable diseases are cancer, cardiovascular disease and diabetes mellitus. This article focuses on communicable diseases (infectious diseases especially viral infections of public health importance. The infections include bacterial, parasitic and viruses. It could be said that fungal infections by the nature of the spread are not of public health concern. The viral infections are transmitted by the respiratory route, water and food borne route, vectors and blood and blood products, sexual route and are of major concern. Efforts are aimed at early detection, prevention by use of vaccines and sentinel surveillance. For the success of public health programmes sentinel surveillance of diseases is mandatory. India has got several programme initiatives addressing the problem. The programs include IDSP, VBDCP and NACO. The approximate cumulative annual prevalence of infectious disease in India ranges from 100 to 200 million individuals affected in one year. India should aim to improve case detection by strengthening laboratory services with manpower training and nationwide quality control scheme, sentinel surveillance activity and prevention by improving the efficiency and scope of UIP. Also, creation of a single portal of infectious disease data handling hub to collect information from different sources will help avoid overlap and duplication of reporting.

  7. INTERNATIONALIZATION AND CLUSTER POTENTIALS WITH SPECIAL EMPHASIS ON WOOD-PROCESSING SECTOR IN BOSNIA AND HERZEGOVINA

    Directory of Open Access Journals (Sweden)

    Mirha Bico-Car

    2013-06-01

    Full Text Available Small and medium enterprises (SMEs in all national economies are generators of growth and development. This statement is confirmed by the fact that SMEs in the European Union (EU account for 90% of the total number of companies, and that more than 23 million of these companies employ over 67% of the workforce in the private sector. European law on small and medium enterprises creates favorable regulatory conditions for their further growth. However, adequate attention has not yet been paid to this sector in Bosnia and Herzegovina (BiH. Economic growth in pre-war Yugoslavia was based on a system of large company networks from complementary industries which were deliberately designed. War and disintegration of Yugoslavia have disrupted this concept and sparked a series of dilemmas in terms of re-directing and developing the national economy. Many economists have advocated for the restoration of pre-war business giants. Nevertheless, war, institutional destruction and loss of educated and skilled labor, as well as technological obsolescence, loss of previous markets and industries created the opinion that SMEs should first be developed and then connected through networking and clustering. This would eventually lead to the creation of large and powerful production systems. This paper examines how far BiH has progressed in this regard and how consistent is its economic policy. Moreover, this work provides a review of business practices and the potential of clustering, and finally business internationalization of SMEs.

  8. Investigation of photonic band gaps with special emphasis on hyperuniform structures

    OpenAIRE

    Siedentop, Lukas

    2016-01-01

    A toolbox of considerable size was collected within the course of this work that enables the study of photonic meta materials. It is now possible to successfully simulate, fabricate and moreover characterise meta materials with a photonic band gap. This is of great interest for applications, where waveguides are one possible object of interest, as well as fundamental theoretical investigations, namely identify the properties a pattern needs to posses to form such a photonic band gap, for exam...

  9. Planing and designing large energy systems with a special emphasis on their impact on the environment

    OpenAIRE

    Luburić Veselin D.; Bakrač Saša T.; Milanović Miško M.

    2015-01-01

    U radu se analizira uticaj planiranja i projektovanja velikih elektroenergetskih sistema na životnu sredinu, kao što je Detaljni prostorni plan (DPP) postavljanja 400 kV optičkog kabla od Crnogorskog primorja do Pljevalja. To predstavlja vrlo kompleksan i multidisciplinaran posao i podrazumeva analizu niza bitnih faktora, kao i uzročnoposledičnih veza koje jedan takav sistem može proizvesti. U analizi se rukovodilo činjenicom da se radi o atipičnom primeru, s planerskog i izvedbenog aspekta n...

  10. Proteomics in Argentina - limitations and future perspectives: A special emphasis on meat proteomics.

    Science.gov (United States)

    Fadda, Silvina; Almeida, André M

    2015-11-01

    Argentina is one of the most relevant countries in Latin America, playing a major role in regional economics, culture and science. Over the last 80 years, Argentinean history has been characterized by several upward and downward phases that had major consequences on the development of science in the country and most recently on proteomics. In this article, we characterize the evolution of Proteomics sciences in Argentina over the last decade and a half. We describe the proteomics publication output of the country in the framework of the regional and international contexts, demonstrating that Argentina is solidly anchored in a regional context, showing results similar to other emergent and Latin American countries, albeit still far from the European, American or Australian realities. We also provide a case-study on the importance of Proteomics to a specific sector in the area of food science: the use of bacteria of technological interest, highlighting major achievements obtained by Argentinean proteomics scientists. Finally, we provide a general picture of the endeavors being undertaken by Argentinean Proteomics scientists and their international collaborators to promote the Proteomics-based research with the new generation of scientists and PhD students in both Argentina and other countries in the Southern cone. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Effects of bioprocessed antinutritional factors on bean protein quality : with special emphasis on Phaseolus vulgaris L.

    NARCIS (Netherlands)

    Savelkoul, F.

    1994-01-01

    Legumes, e.g. beans and peas, can contain antinutritional factors. Some varieties of faba beans (Vicia faba), soya beans (Glycine max ) and white kidney beans (Phaseolus vulgaris) can contain in their raw state antinutritional

  12. Gnostic hermeneutics of Islam, with special emphasis on the transcendental philosophy of Mulla Sadra Shirazi

    Directory of Open Access Journals (Sweden)

    Halilović Seid

    2014-01-01

    Full Text Available In all periods of brilliant Gnostic heritage of Islam, much has been written about esoteric meanings and secret depths of the Qur'an and traditions. Numerous representatives of Muslim practical and doctrinal gnosis have extensively interpreted the most sophisticated teachings of sacred religious texts revealing them in the light of their intuitive knowledge of the human's soul path of development, and the highest realities of the metaphysical sphere of existence. In this paper, we first determine the basic historical contexts and terminology of the process of Gnostic hermeneutics of Islam, and then we extensively analyze the most important ontological-anthropological and methodological principles of the process. As the aforementioned rational principles have been elaborated on in an established demonstrative-philosophical language in the school of transcendental philosophy - the most dominant traditional philosophical school of Islam, we will use here primarily the method of detailed analysis of the contents of the most influential works of the renowned founder of the school, Mulla Sadra Shirazi. We show that the esoteric depths of the primordial Qur'anic messages are recognized in the same way that the existence of numerous profound spheres of the entire universe and human beings is established. We will also explain that in the process of hermeneutic discovering of layered secrets of the Qur'an and traditions, Muslim Gnostics do not reject the exoteric meanings of Qur'anic message, but they deepen these meanings, freeing them from unnecessary restrictions of material forms and thus reach the essential mystery of God's speech.

  13. 77 FR 21778 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-11

    ... announced below concerns Development and Testing of a Clinic-Based Intervention to Increase Dual Protection against Unintended Pregnancy and STDs among High Risk Female Teens, FOA DP12- 001, initial review. In... Protection against Unintended Pregnancy and STDs among High Risk Female Teens, FOA DP12-001, initial review...

  14. Human-Mouse Dosimetry in Clinical Radioimmunotherapy - Special Emphasis on Pediatric Applications

    International Nuclear Information System (INIS)

    Kairemo, K.J.A.; Pyyry, J.; Heiskanen, T.; Flux, G.; Fisher, D.R.

    2009-01-01

    Monoclonal antibody ('MAB') has been developed for targeting secretory alpha-fetoprotein in hepatic tissue. We have used these MABs for radioimmunotherapy and dose planning of recurrent hepatoblastoma, a rare childhood malignancy This MAB has been labelled with In- 111 and Y-90 for clinical purposes, and can be applied for diagnosis and therapy of liver neoplasms. Physiology based pharmacokinetic (PBPK) modeling and simulation is a useful method for prediction of biodistribution of macromolecules, it can enhance our understanding of the underlying mechanisms and hence may help in rational design of diagnostic and therapeutic agents. Here we also discuss PBPK modeling and simulation of this MAB in mice without tumor and in a pediatric patient. In the clinical study, radiopharmacokinetic parameters for this MAB ( 111 In-DOTA-hAFP31 IgG) were calculated after serial quantitative whole body scans in a child with hepatoblastoma. A 3-D dose planning computer program was used to calculate tumor doses for In-111 and Y-90, the active tumor was delineated on PET/CT images and tumor dose calculation was done based on the In-111-MAB SPECT data using dose point kernel approach both for In-111 and Y-90. The results were compared with MIRD doses obtained for organs in SPECT imaging field, i.e. bone marrow, heart, kidneys, liver, spleen, lungs. The simulated results were fitted to experimental time series data by varying parameters which were not fixed a priori. From quantitative serial imaging based on 8 whole body images at 0-168 hrs using In-111- MAB, the half-lives of spleen, lungs, kidneys and whole body were 502 hrs, 230 hrs, 193 hrs and 490 hrs, respectively. The measured blood half-life was 132 hrs, after a total MAB dose of 50 mg and In-111 activity of 105 MBq. The presumed Y-90 dose based on this kinetic behavior was 43 MBq which should had given 0.3Gy bone marrow dose with assumption of bone marrow: blood ratio 0.4 for IgG. The calculated MIRD Y-90 doses were for cardiac wall 0.75 Gy, liver 0.62 Gy, spleen 0.51 Gy and bone marrow 0.053 Gy, and the effective whole body dose was 0.18 Gy, i.e. 4.23 mGy/MBq. The 3-D program demonstrated the mean doses in normal tissues as follows: heart 0.58 Gy, liver 0.48 Gy, spleen 0.37 Gy and bone marrow 0.34 Gy. The actual liver tumor dose according to the 3-D calculations was in average 0.51 Gy with range of 0.22-0.96 Gy. It was demonstrated that the PBPK model describes the main features of the pharmacokinetics of the studied systems. It was also shown that simulation can be used for evaluating the parameters of the system and scaling up the pharmacokinetics of MAB from mice to man. As a conclusion, according to the data, probably 5-6 fold activity could have been infused without limiting toxicity. Using current activity only minor change in the biomarker behavior was observed, but with higher activities the response could have been evaluated. This data demonstrates that radioimmunotherapy procedure may be applied in childhood solid tumors, if appropriate dosimetry software is available. It was also concluded that the transvascular permeabilities are the most important parameters and more research is needed to enable prediction of permeabilities from molecular characteristics of macromolecules. It would also be necessary to understand better and describe with a more detailed model the microstructure of the tumor and to measure or predict the antigen concentration in tumor. Non-specific, non-saturable binding in other organs/tissues should be understood better and the kinetic constants of the binding should be measured experimentally. Although the metabolism and clearance were neglected in this study they need to be included in more detailed studies. Also the intracellular trafficking of macromolecules, which was not included in this study, shall be included in the more accurate models. (author)

  15. Quorum sensing in Acinetobacter: with special emphasis on antibiotic resistance, biofilm formation and quorum quenching

    Directory of Open Access Journals (Sweden)

    Bindu Subhadra

    2016-02-01

    Full Text Available Acinetobacter is an important nosocomial, opportunistic human pathogen that is gradually gaining more attention as a major health threat worldwide. Quorum sensing (QS is a cell-cell communication system in which specific signaling molecules called autoinducers accumulate in the medium as the population density grows and control various physiological processes including production of virulence factors, biofilm and development of antibiotic resistance. The complex QS machinery in Acinetobacter is mediated by a two-component system which is homologous to the typical LuxI/LuxR system found in Gram-negative bacteria. This cell signaling system comprises of a sensor protein that functions as autoinducer synthase and a receptor protein which binds to the signal molecules, acyl homoserine lactones inducing a cascade of reactions. Lately, disruption of QS has emerged as an anti-virulence strategy with great therapeutic potential. Here, we depict the current understanding of the existing QS network in Acinetobacter and describe important anti-virulent strategies developed in order to effectively tackle this pathogen. In addition, the prospects of quorum quenching to control Acinetobacter infections is also been discussed.

  16. Fire Distribution in Peninsular Malaysia, Sumatra and Borneo in 2015 with Special Emphasis on Peatland Fires.

    Science.gov (United States)

    Miettinen, Jukka; Shi, Chenghua; Liew, Soo Chin

    2017-10-01

    In this paper, we analyze the spatio-temporal distribution of vegetation fires in Peninsular Malaysia, Sumatra, and Borneo in the severe El Niño year of 2015, concentrating on the distribution of fires between mineral soils and peatland areas, and between land cover types in peatland areas. The results reveal that 53% of all Moderate Resolution Imaging Spectroradiometer (MODIS) fire detections were recorded in peatlands that cover only 12% of the study area. However, fire occurrence in the peatland areas was highly dependent on land cover type. Pristine peat swamp forests (PSF) experienced only marginal fire activity (30 fire detections per 1000 km 2 ) compared to deforested undeveloped peatlands (831-915 fire detections per 1000 km 2 ). Our results also highlight the extreme fire vulnerability of the southern Sumatran and Bornean peatlands under strong El Niño conditions: 71% of all peatland hotspots were detected in the provinces of South Sumatra and Central Kalimantan, which contain 29% of peatlands in the study area. Degraded PSF and all deforested peatland land cover types, including managed areas, in the two provinces were severely affected, demonstrating how difficult it is to protect even managed drained agricultural areas from unwanted fires during dry periods. Our results thereby advocate rewetting and rehabilitation as the primary management option for highly fire prone degraded undeveloped peatland areas, whenever feasible, as a means to reduce fire risk during future dry episodes.

  17. 77 FR 73662 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-12-11

    ... announced below concerns Occupational Safety and Health Education and Research Centers (ERC) PAR 10-217... evaluation of applications received in response to ``Occupational Safety and Health Education and Research... Officer, CDC/NIOSH, 626 Cochrans Mill Road, Mailstop P-05, Pittsburgh, Pennsylvania 15236, Telephone: (412...

  18. 77 FR 44618 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-07-30

    ... Officer, National Institute for Occupational Safety and Health, CDC, 1095 Willowdale Road, Mailstop G800... announced below concerns the World Trade Center Health Program Outreach and Education Plan RFA-OH12-1201... Diagonal Road, Alexandria, Virginia 22314, Telephone: (703) 684-5900. Status: The meeting will be closed to...

  19. Agroecological Responses of Heavy Metal Pollution with Special Emphasis on Soil Health and Plant Performances

    Directory of Open Access Journals (Sweden)

    Vaibhav Srivastava

    2017-10-01

    Full Text Available With modern day urbanization and industrialization, heavy metal (HM contamination has become a prime concern for today's society. The impacts of metal contamination on agriculture range from the agricultural soil to the produce in our food basket. The heavy metals (HMs and metalloids, including Cr, Mn, Co, Ni, Cu, Zn, Cd, Sn, Hg, Pb, among others, can result in significant toxic impacts. The intensification of agricultural land use and changes in farming practices along with technological advancement have led to heavy metal pollution in soil. Metals/metalloids concentrations in the soil are increasing at alarming rate and affect plant growth, food safety, and soil microflora. The biological and geological reorganization of heavy metal depends chiefly on green plants and their metabolism. Metal toxicity has direct effects to flora that forms an integral component of ecosystems. Altered biochemical, physiological, and metabolic processes are found in plants growing in regions of high metal pollution. However, metals like Cu, Mn, Co, Zn, and Cr are required in trace amounts by plants for their metabolic activities. The present review aims to catalog major published works related to heavy metal contamination in modern day agriculture, and draw a possible road map toward future research in this domain.

  20. Pathomorphological and microbiological studies in sheep with special emphasis on gastrointestinal tract disorders

    Directory of Open Access Journals (Sweden)

    Sarvan Kumar

    2015-08-01

    Full Text Available Aim: The present study was envisaged to elucidate the pathomorphological and microbiological aspects of gastrointestinal tract (GIT disorders of sheep/lambs. Materials and Methods: Samples for research were collected from 12 sheep died with a history of GIT disorders which were brought for post-mortem examination to the Department of Veterinary Pathology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, for pathomorphological and microbiological examination. Results: Gross pathological changes in various organs noticed were abomasitis, congestion and hemorrhages in intestine; necrotic foci on liver surface; enlarged, hard, and indurated mesenteric lymph nodes, hydropericardium, congestion, hemorrhages and consolidation of lungs and congestion and soft kidneys as the major change. On histopathological examination, there were abomasitis with leukocyte infiltration, enteritis with desquamation of mucosal epithelium and goblet cell hyperplasia, lymphadenitis with depletion of lymphocytes in the germinal center of lymphoid follicle, and splenitis with depletion of lymphocytes in the white pulp. In the liver congestion, degenerative changes in hepatocytes including cloudy swelling, fatty changes, congestion in sinusoids, and dilatation of sinusoids leading to atrophy of hepatocytes. Lungs evidenced edema, congestion, emphysema, serous inflammation, thickening of interlobular septa, fibrinous pleuritis, and peribronchiolar lymphoid follicle formation. Heart revealed sarcocystosis, fibrinous pericarditis, and hyalinization of the myocardium. In kidneys, congestion, focal interstitial nephritis, hyaline degeneration, and coagulative necrosis were seen. For microbiological aspects; cultural isolation was done from samples of liver, abomasum, mesenteric lymph nodes, spleen, heart blood, lungs, and kidneys from the carcasses of sheep/lambs. Escherichia coli was the only bacterium isolated during present studies. E. coli isolates from different tissues of carcasses of sheep/lambs were subjected to in-vitro drug sensitivity testing. Ciprofloxacin, cefixime, polymyxin B, amoxicillin + sulbactam, and amoxicillin + clavulanic acid were the most sensitive drugs followed by amikacin, ofloxacin, ampicillin, co-trimoxazole, and amoxicillin. Conclusions: From the present study, it is reasonable to conclude that the major etiopathological cause of GIT disorders in sheep was E. coli infection, which causes a pathomorphological effect on various cadaver organs viz. abomasum, intestine, liver, mesenteric lymph nodes, lungs, spleen, kidneys, and heart followed by parasitic infection of Haemonchus contortus.

  1. Special Operations Forces Language and Culture Needs Assessment Project: Training Emphasis: Language and Culture

    Science.gov (United States)

    2010-02-25

    fluency in both the target language and English. In order to score well on the DLPT V you need to have an extensive vocabulary in both the target...environment IOT cement what you learned in Phase 1; Phase 3 = maintenance training which includes shorter periods of both classroom and immersion. Though

  2. Magnetic resonance imaging in low back pain and sciatica with special emphasis on the postdiskectomy period

    International Nuclear Information System (INIS)

    Annertz, M.

    1994-01-01

    The diagnostic capability of magnetic resonance (MR) imaging at 0.3 T was evaluated and compared with other modalities in patients with previous disk surgery and remaining or recurrent sciatica, and in patients with spondylolisthesis and sciatica. In the early postoperative period after successful lumbar diskectomy, MR showed a large amount of abnormal soft tissue in the anterior epidural space, without correlation with clinical symptoms. In the late postoperative period, contrast-enhanced MR provided the best correlation with surgical findings, compared with CT and myelography, in discriminating recurrent/remaining disk herniation from epidural fibrosis in patients with the lumbar postdiskectomy syndrome. Contrast-enhanced MR could not demonstrate any differences regarding presence and extent of epidural fibrosis between symptomatic and asymptomatic patients. In spondylolisthesis, MR gave excellent information about the root canals and the degree of nerve root stretching and compression, which was not possible to evaluate with myelography. MR at 0.3 T provided information comparable to that reported from examinations performed with superconducting MR scanners, and is well suited as the imaging modality in the evaluation of lumbar spine disorders. After introducing MR at 0.2 and 0.3 T with vertical magnetic fields as the first neuroradiological modality, instead of myelography or CT, in the evaluation of the soft tissues of the lumbar spine in patients with low back pain and sciatica, a significant increase in the number of patients examined, a moderate increase in the total cost of investigations, and a significant decrease in the cost per investigated and per operated patient was noted

  3. Coherent efforts in relation to COPD patients with special emphasis on the quality and technological solutions

    DEFF Research Database (Denmark)

    Bagger, Bettan; Vestergaard*, Kitt; Andresen, Mette

    Keywords: COPD, quality, clinical pathways, daily life, competences, welfare technology Background: Focus in Health Service moves towards quality and hence focus is on results that create quality in healthcare services. Technologies are assumed to promote more consistent quality in health care......, Hospital Naestved investigate COPD patients’ and health professionals’ perspectives with respect to their assessments of quality in clinical pathways and daily life focusing on clinical pathways, interdisciplinary sharing of knowledge and use of technology. Identification of parameters will be important...... recruits informants. Methodology: qualitative in depth interviews A literature review has been done to identify COPD patients and health professionals’ assessment of parameters for quality in clinical pathways and daily life. The study is a phenomenological explorative study focusing upon the meaning...

  4. Microbiological Quality of Raw Dried Pasta from the German Market, with Special Emphasis on Cronobacter Species.

    Science.gov (United States)

    Akineden, Ömer; Murata, Kristina Johanna; Gross, Madeleine; Usleber, Ewald

    2015-12-01

    The microbiological quality of 132 dried pasta products available on the German market, originating from 11 different countries, was studied. Sample materials included soft or durum wheat products, some of which produced with other ingredients such as eggs, spices, or vegetables. Parameters included hygiene indicators (aerobic plate count, mold count, the presence of Enterobacteriaceae) and pathogenic/toxinogenic bacterial species (Salmonella spp., Staphylococcus aureus, presumptive Bacillus cereus, and Cronobacter spp.). The overall results of hygiene parameters indicated a satisfactory quality. Salmonella was not found in any sample. Three samples were positive for S. aureus (10(2) to 10(4) colony forming unit (CFU)/g). Presumptive B. cereus at levels of 10(3) to 10(4) CFU/g were detected in 3 samples. Cronobacter spp. were isolated from 14 (10.6%) products. Of these, 9 isolates were identified as C. sakazakii, 2 each as C. turicensis and C. malonaticus, and 1 as C. muytjensii. The isolates were assigned to 9 multilocus sequence typing (MLST) sequence types and to 14 different PFGE profiles. Although pasta products are typically cooked before consumption, some consumers, and children in particular, may also eat raw pasta as nibbles. Raw pasta seems to be a relevant source of exposure to dietary Cronobacter spp., although health risks are probably restricted to vulnerable consumers. High numbers of presumptive B. cereus as found in some samples may be a risk after improper storage of cooked pasta products because toxinogenic strains are frequently found within this species. © 2015 Institute of Food Technologists®

  5. History on the biological nitrogen fixation research in graminaceous plants: special emphasis on the Brazilian experience.

    Science.gov (United States)

    Baldani, José I; Baldani, Vera L D

    2005-09-01

    This review covers the history on Biological Nitrogen Fixation (BNF) in Graminaceous plants grown in Brazil, and describes research progress made over the last 40 years, most of which was coordinated by Johanna Döbereiner. One notable accomplishment during this period was the discovery of several nitrogen-fixing bacteria such as the rhizospheric (Beijerinckia fluminensis and Azotobacter paspali), associative (Azospirillum lipoferum, A. brasilense, A. amazonense) and the endophytic (Herbaspirillum seropedicae, H. rubrisubalbicans, Gluconacetobacter diazotrophicus, Burkholderia brasilensis and B. tropica). The role of these diazotrophs in association with grasses, mainly with cereal plants, has been studied and a lot of progress has been achieved in the ecological, physiological, biochemical, and genetic aspects. The mechanisms of colonization and infection of the plant tissues are better understood, and the BNF contribution to the soil/plant system has been determined. Inoculation studies with diazotrophs showed that endophytic bacteria have a much higher BNF contribution potential than associative diazotrophs. In addition, it was found that the plant genotype influences the plant/bacteria association. Recent data suggest that more studies should be conducted on the endophytic association to strengthen the BNF potential. The ongoing genome sequencing programs: RIOGENE (Gluconacetobacter diazotrophicus) and GENOPAR (Herbaspirillum seropedicae) reflect the commitment to the BNF study in Brazil and should allow the country to continue in the forefront of research related to the BNF process in Graminaceous plants.

  6. Pork quality with special emphasis on colour and its changes during storage

    OpenAIRE

    Maria Bocian; Hanna Jankowiak; Patrycja Reszka; Sandra Banaszak

    2018-01-01

    The aim of the study was to evaluate the quality of pork meat, including its colour after 24, 48, and 72 hours from the slaughter and its changes during storage. The meat was obtained from 52 crossbreed porkers F1 (Polish Large White x Polish Landrace), gilts and hogs in equal amounts. The assessment of the quality of the meat was performed in 48 hours after slaughter on the samples of the longissimus lumborum muscle. The meat was analysed in respect to its acidity (pH45 and pH48h), technolog...

  7. A review of gastrointestinal microbiology with special emphasis on molecular microbial ecology approaches

    International Nuclear Information System (INIS)

    Mackie, R.I.; Cann, I.K.O.

    2005-01-01

    All animals, including humans, are adapted to life in a microbial world. Large populations of micro-organisms inhabit the gastrointestinal tract of all animals and form a closely integrated ecological unit with the host. This complex, mixed, microbial culture can be considered the most metabolically adaptable and rapidly renewable organ of the body, which plays a vital role in the normal nutritional, physiological, immunological and protective functions of the host animal. Bacteria have traditionally been classified mainly on the basis of phenotypic properties. Despite the vast amount of knowledge generated for ruminal and other intestinal ecosystems using traditional techniques, the basic requisites for ecological studies, namely, enumeration and identification of all community members, have limitations. The two major problems faced by microbial ecologists are bias introduced by culture-based enumeration and characterization techniques, and the lack of a phylogenetically-based classification scheme. Modem molecular ecology techniques based on sequence comparisons of nucleic acids (DNA or RNA) can be used to provide molecular characterization while at the same time providing a classification scheme that predicts natural evolutionary relationships. These molecular methods provide results that are independent of growth conditions and media used. Also, using these techniques, bacteria can be classified and identified before they can be grown in pure culture. These nucleic acid-based techniques will enable gut microbiologists to answer the most difficult question in microbial ecology: namely, describing the exact role or function a specific bacterium plays in its natural environment and its quantitative contribution to the whole. However, rather than replacing the classical culture-based system, the new molecular-based techniques can be used in combination with the classical approach to improve cultivation, speciation and evaluation of diversity. The study of microbial ecology in gut ecosystems involves investigation of the organisms present (abundance and diversity), their activity (usually determined in vitro, but in vivo activity or expression of activity is really required), and their relationship with each other and the host animal (synergistic and competitive interactions). This entails the study and measurement of many types of interactions, both beneficial and competitive. Traditionally, media for isolation of bacteria from natural environments are basically of two types: those that simulate the habitat in broad terns, i.e. habitat-simulating and non-selective media; and those designed to enumerate and isolate bacteria of a particular type or from a specific biochemical niche, i.e. niche-simulating or functional or nutritional group analysis. A third type, less important in the ecological sense, does not simulate the habitat, is often highly selective and is used to isolate specific bacterial groups. Specific nutritional types of bacteria may be isolated by the use of enrichment media. This type of medium, basically a refinement of the habitat-simulating medium, is widely used in environmental microbiology and has been applied with some success to the gut ecosystem. Although estimates of microbial number rely on culture techniques, microscopic examination is a most useful technique for evaluating the efficacy of other enumeration approaches. The combination of microscopy with specific phylogenetic stains or fluorescent antibodies enables bacteria to be specifically detected and enumerated in mixed populations. The introduction of genetic-based technologies, and in particular those relating to 16S rRNA typing, are rapidly replacing conventional detection and enumeration methods in studies of the mammalian intestinal tract. Although molecular techniques promise a fuller and more accurate description of the true diversity, structure and dynamics of complex microbial communities than the present culturing studies, each technique suffers from its own experimental bias and selectivity. Different methods used for direc t molecular detection are reviewed in the paper. Attention is given to molecular characterization of complex communities; in particular, the application of molecular fingerprinting techniques to examine diversity and community structure in complex gut bacterial communities. Denaturing or temperature gradient gel electrophoresis (DGGE/TGGE) methods have been successfully applied to the analysis of human, pig, cattle, dog and rodent intestinal populations. In future, genomics technologies will provide gut microbial ecologists with their best opportunity for a complete or global analysis of the molecular mechanisms involved in metabolism and regulation within the bacterial community and between host and resident microbes. Molecular microbial techniques have been widely and successfully used to study microbial diversity in environmental microbiology but have had limited application in the gastrointestinal ecosystem. (author)

  8. Baking loss of bread with special emphasis on increasing water holding capacity.

    Science.gov (United States)

    Kotoki, D; Deka, S C

    2010-01-01

    Potato flour (PF), hydroxypropyl methylcellulose (HPMC) and honey were used as baking agents and their effects on baking loss and sensory quality were studied. PF at 1, 2 and 4% levels decreased baking loss followed by HPMC and honey. Water absorption was substantially high with the HPMC (70.8-80.8%) and PF (61.7-71.7%) compared to honey and normal standard bread. PF incorporation increased shelf-life (6-7 days) as compared to HPMC and honey. HPMC incorporated bread had higher moisture content (36.8-38.0%) followed by PF (34.5-35.8%) and honey (34.7%). The ash content was in the order of PF (1%) > honey (4%) > PF (2%) > normal bread > HPMC (0.5 g) > PF (4%) > HPMC (1 g) > HPMC (1.5 g). PF incorporated bread had sensorily highest acceptance followed by HPMC and honey.

  9. 75 FR 18848 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Prevention...

    Science.gov (United States)

    2010-04-13

    ... Comparative Effectiveness Research Program, DP 10-003, Initial Review In accordance with Section 10(a)(2) of..., Management Analysis and Services Office, CDC, pursuant to Public Law 92-463. Matters To Be Discussed: The... to ``Prevention Research Centers Comparative Effectiveness Research Program, DP 10-003.'' Contact...

  10. Governmental intervention approaches to promote renewable energies—Special emphasis on Japanese feed-in tariff

    International Nuclear Information System (INIS)

    Ayoub, Nasser; Yuji, Naka

    2012-01-01

    Almost all countries have issued laws and regulations to promote renewable energy (RE). However, the applications and motivations of such laws as well as achievements have been different. Currently, the Japanese government has announced its targets to expand the electricity feed-in tariff scheme for solar power, along with other energy sources, within two years to meet the goal set by the Japanese Prime Minister who, in the 15th United Nations Climate Change Conference (COP15) held in September 2009, proclaimed to cut 25% of greenhouse gas (GHG) emissions from the 1990 levels by 2020. In this paper, the current Japanese energy policies and measures for promoting RE in comparison to popular methods followed worldwide are explored. Furthermore, a Least Cost Feed-in Tariff (LCFIT) Simulation Model for Japanese case was developed to calculate the optimal mix of technologies to reach certain targets. The LCFIT also calculates the tariff that should be proposed for each technology and the total cost for the program with and without a carbon tax and estimates the premium added to the bill of the customer every month. - Highlights: ► RE governmental interventions vary with country's economical, social and topological condition. ► LCFIT Model showed that Japan can apply the FiT system with reasonable burdens on the customers. ► Applying 20% of carbon tax can lead to declining the burdens on the customer by about 32%–45%. ► The R and D expenditures on RE is almost one-fourth that of nuclear power in some countries. ► Japanese scenarios seem very satisfying compared to that of Germany and other European countries.

  11. Simulations of Scatterometry Down to 22 nm Structure Sizes and Beyond with Special Emphasis on LER

    Science.gov (United States)

    Osten, W.; Ferreras Paz, V.; Frenner, K.; Schuster, T.; Bloess, H.

    2009-09-01

    In recent years, scatterometry has become one of the most commonly used methods for CD metrology. With decreasing structure size for future technology nodes, the search for optimized scatterometry measurement configurations gets more important to exploit maximum sensitivity. As widespread industrial scatterometry tools mainly still use a pre-set measurement configuration, there are still free parameters to improve sensitivity. Our current work uses a simulation based approach to predict and optimize sensitivity of future technology nodes. Since line edge roughness is getting important for such small structures, these imperfections of the periodic continuation cannot be neglected. Using fourier methods like e.g. rigorous coupled wave approach (RCWA) for diffraction calculus, nonperiodic features are hard to reach. We show that in this field certain types of fieldstitching methods show nice numerical behaviour and lead to useful results.

  12. ADVERTISING INDUSTRY - TRENDS, OPPORTUNITIES AND CHALLENGES WITH SPECIAL EMPHASIS OF CHINESE TOURISM

    Directory of Open Access Journals (Sweden)

    Misko Dzidrov

    2010-12-01

    Full Text Available Now day advertising has craftily become an inescapable companion of modern life that we can't escape and avoid it, truly it’s an intrinsic part of our daily lives. Advertising affects everyone’s life and influences many purchasers. Consumer turns to advertising for its informativeness, as well as its entertainment value. In November 2001, China joined the World Trade Organization (WTO and became a formal member of the free trade club. China's accession to the WTO came after the country had economic reforms and significant growth of Chinese economy. In the same period advertising start booming in China (early 1979; it has become dramatically an increasing important business, industry, and custom artefact in the country. A lot of researches have been made on advertising industry in the west and are one of everyday activity in the current market, but researches about Chinese advertising about tourism market has generally been limited to journal articles. The purpose of this research is to: Investigate how consumers read and understand advertising in China, mainly tourism advertising; To learn how Chinese consumers react to TV and print advertisements; Examine what role advertising playing in marketing and how it perused people of China - moreover which channel is most preferable to advertise tourism offers in Chinese society.

  13. Immune Modulation by Vitamin D: Special Emphasis on Its Role in Prevention and Treatment of Cancer.

    Science.gov (United States)

    Pandolfi, Franco; Franza, Laura; Mandolini, Claudia; Conti, Pio

    2017-05-01

    Vitamin D has been known to be involved in mineral and bone homeostasis for many years. In the past its main use was in treating osteoporosis and rickets. In recent years it was found that vitamin D is an immune-modulating agent and may also have a role in several diseases, including autoimmune diseases. The immune-modulating effects appear to be mediated by vitamin D interaction with the vitamin D receptor (VDR) that has transcriptional effects and is expressed on various cell types, especially those of the immune system. Immunologic and rheumatologic diseases were the first to be studied, but at the moment the spotlight is on the interactions between tumor cells and vitamin D. This review focuses on four forms of cancer that apparently benefit from a vitamin D supplementation during treatment: prostate, breast, and colorectal cancers and melanoma. Several studies reported that differences exist between white and black patients, which we discuss in the review. We systematically searched PubMed for studies published in English. The search terms included vitamin D, cancer, breast, colorectal, prostate, and melanoma. Our findings show that vitamin D has the potential to become a valid coadjuvant in the treatment of cancer. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

  14. A bibliographical survey of bruxism with special emphasis on non-traditional treatment modalities.

    Science.gov (United States)

    Nissani, M

    2001-06-01

    After proposing a common-sense definition of bruxism, this partial review distills its various symptoms and consequences from the literature. That literature suggests that the splint-the most popular treatment modality-falls short in some respects. The research literature is even less sanguine about the efficacy of such other traditional therapies as sound alarms and stress reduction. Given the limited success of traditional approaches, and given, moreover, the high incidence of bruxism and its harmful consequences, clinicians may occasionally be interested in experimenting with non-intrusive, safe, less widely known, treatment modalities. To meet this need, this review-unlike all other reviews of the subject-focuses on such comparatively unpopular or recent approaches.

  15. 3Rs-respecting animal models in radiopharmaceutical research with a special emphasis to monoclonal antibodies

    International Nuclear Information System (INIS)

    Balogh, Lajos; Thuróczy, Julianna; Pöstényi, Zita; Kovács-Haász, Veronika; Lovas, Melinda; Polyák, András; Jánoki, Győző A.; Leyva Montana, René

    2016-01-01

    In better developed human medical centres hybrid (or fusion) diagnostic imaging (PET/CT, SPECT/CT, PET/MRI …) is available for clinicians to detect, localize, stage and follow-up theire patients suffering a wide variety (oncological, cardiovascular, neurological, orthopaedic …) of diseases. Easy to understand that not only human and veterinary clinical but numerous research applications could be implemented using these novel digital imaging methods. The use of hybrid equipments is not simply an expensive toy in researcher’s hands but and effective tool that serves 2 out of the 3 Rs (Refinement and Reduction) requirements as well. Hybrid (fusion) imaging method allows high-resolution pictures including correct anatomical structures and quantized functional data as altogether after radiolabelled ligand applications. Serial images could be taken using only one single anesthetized animal that must not be exterminated at the end of process. The re-use of laboratory animals allowing us to compare the characteristics of different labelled molecules in the very same biological model. Spontaneously diseased canine, feline and exotic animals is a constant source of animal models for the biomedical research and represents a great choice to replace laboratory animals. Osteosarcoma, mammary gland carcinoma, thyroid carcinoma, brain tumours and a few others in dogs or cats might be the best known animal models of the appropriate human diseases. Diagnosing and then treating them with the most promising human methods (including cold MoAbs, immunotherapy, radiolabelled ligands ...) is a chance for the suffering animals, a new hope for owners and referral vets - and parallel applicable data for human oncologists and translational researchers. Authors wish to share with audience their 20 years expert in the field and hope to find friends and co-operators among them. (author)

  16. Effects of global warming on fish reproductive endocrine axis, with special emphasis in pejerrey Odontesthes bonariensis.

    Science.gov (United States)

    Miranda, Leandro Andrés; Chalde, Tomás; Elisio, Mariano; Strüssmann, Carlos Augusto

    2013-10-01

    The ongoing of global warming trend has led to an increase in temperature of several water bodies. Reproduction in fish, compared with other physiological processes, only occurs in a bounded temperature range; therefore, small changes in water temperature could significantly affect this process. This review provides evidence that fish reproduction may be directly affected by further global warming and that abnormal high water temperature impairs the expression of important genes throughout the brain-pituitary-gonad axis. In all fishes studied, gonads seem to be the organ more readily damaged by heat treatments through the inhibition of the gene expression and subsequent synthesis of different gonadal steroidogenic enzymes. In view of the feedback role of sex steroids upon the synthesis and release of GnRH and GtHs in fish, it is possible that the inhibition observed at brain and pituitary levels in treated fish is consequence of the sharp decrease in plasma steroids levels. Results of in vitro studies on the inhibition of pejerrey gonad aromatase expression by high temperature corroborate that ovary functions are directly disrupted by high temperature independently of the brain-pituitary axis. For the reproductive responses obtained in laboratory fish studies, it is plausible to predict changes in the timing and magnitude of reproductive activity or even the total failure of spawning season may occur in warm years, reducing annual reproductive output and affecting future populations. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. 75 FR 7283 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Science.gov (United States)

    2010-02-18

    ... Interface Activities for Avian Influenza and Other Zoonotic Diseases, Funding Opportunity Announcement (FOA... Interface Activities for Avian Influenza and other Zoonotic Diseases, FOA CK10-001.'' Contact Person for... Office, has been delegated the authority to sign Federal Register notices pertaining to announcements of...

  18. The influence of climate change to European Lakes, with a special emphasis in the Balkan Region

    International Nuclear Information System (INIS)

    Kuusisto, Esko

    2004-01-01

    There are almost one and half million lakes in Europe, if small water bodies with an area down to 0.001 km 2 are included. The total area of lakes is over 200.000 km 2 , in addition the man-made reservoirs cover almost 100.000 km 2 . The largest lakes are located in the zone extending from southwestern Sweden through Finland to Russia, but there are many important lakes also in central and southern Europe. The Balkan countries have altogether about ten thousand lakes with a total area of over 4000 km 2 and total volume of almost loo km 3 . Over half of the total volume is in Lake Ohrid, which ranks the seventh in Europe both as to the volume and as to the maximum depth. However, there are around thirty lakes in Europe with their surface area larger than that of Lake Ohrid. In addition to the lakes, the Balkan countries also have thousands of reservoirs with a total water storage capacity of over 50 km 3 . The response of European lakes to climate change can be discussed by dividing the lakes into five categories: 1) deep temperate lakes, 2) shallow temperate lakes, 3) mountain lakes, 4) boreal lakes and 5) arctic lakes. The lakes in the Balkan region fall belong into the first three categories. Most of the deep temperate lakes are warm monomictic; convective overturn occurs in winter or early spring. The future climate change may suppress this overturn, giving these lakes the classification of oligomictic. This implies the enhancement of anoxic bottom conditions and an increased risk of eutrophication. The oxygen conditions can also be expected to deteriorate due to increased bacterial activity in deep waters and superficial bottom sediment. In shallow temperate lakes, higher water temperatures in the future will induce intensified primary production and bacterial decomposition. The probability of harmful extreme events, e.g. the mass production of algae, will increase. The impacts may extend to fishing and recreational use. In lakes with relatively long water retention times, increased evaporation causes conservative solutes to concentrate. The effect may be enhanced by decreased annual inflows; this risk is particularly relevant in southern Europe.Numerous mountain lakes exist in the Balkan region. These lakes are generally considered; to be very sensitive to environmental changes. Their labile ecosystems react quickly to stresses from outside. Many of these lakes are ultraoligotrophic and are covered with ice every winter.The water balances of many Balkan lakes will be negatively affected both by climate change and increased water withdrawal in the future. This is already exemplified by several important lakes, particularly Lake Prespa, whose water level has dropped by six meters since the 1950s. (Author)

  19. Fine needle aspiration cytology of granulomatous mastitis with special emphasis on microbiologic correlation.

    Science.gov (United States)

    Nemenqani, Dalal; Yaqoob, Nausheen; Hafiz, Momein

    2009-01-01

    To describe the cytomorphology of granulomatous mastitis (GM) and to evaluate the causative agents involved, proven on the basis of microbiologic culture results and polymerase chain reaction (PCR) studies. We retrospectively reviewed the inflammatory breast aspirates reported at King Abdul Aziz Specialist Hospital and Al Hada Armed Forces Hospital, Taif, Kingdom of Saudi Arabia, from January 2000 until March 2008. The pathology reports, clinical information, slides, microbiologic culture results and tuberculosis (TB)/PCR were reviewed. Cases of inflammatory carcinoma or duct ectasia were excluded. A total of 49 cases of inflammatory breast aspirates were identified, of which 15 cases were GM. The microbiologic cultures of all 15 cases were available. Six of 15 cases had positive culture for Brucella melitenses, and 2 cases were positive for TB, which was further confirmed by TB/PCR. The fungal cultures were negative in all the cases. Seven of 15 cases were classified as idiopathic GM. Fine needle aspiration cytology was found to be a useful tool in the early diagnosis of GM and its classification if performed by a pathologist as the material can be submitted for culture. The definitive diagnosis can be established by a combination of the cytomorphologic features and microbiologic studies.

  20. 78 FR 19489 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-04-01

    ... Increase Breast and Cervical Cancer Population--Based Prevention Activities SIP13-066, Panel A, initial... Colorectal Cancer Screening, SIP13-065; and Using Small Media to Increase Breast and Cervical Cancer... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease...

  1. 78 FR 75923 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-12-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease... announced below concerns Clinical, Epidemiologic and Ecologic Factors Impacting the Burden and Distribution... Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the...

  2. PREPARING STUDENTS FOR BUSINESS LANGUAGE EXAMINATION WITH SPECIAL EMPHASIS ON DEVELOPING SPEAKING SKILLS

    Directory of Open Access Journals (Sweden)

    Mária Czellér

    2016-03-01

    Full Text Available Today public awareness of technical language knowledge and the social demand for related language skills are on the rise, and the Hungarian labour market requires an increasingly competent command of foreign languages from professionals involved in business and economics; compliance with these growing demands is reflected in the nature and structure of teaching foreign languages in the Hungarian higher education institutions Due to the high degree of institutional autonomy each Hungarian university has the right to work out its own language teaching policy and adopt it in its training programme. This paper will show that foreign language study at Hungarian universities can be devoted either to general language or language for specific purposes. These criteria can differ according to the field of study. Given that obtaining a language exam certificate is a pre-requisite of graduation, the role of academic education in providing students with the required knowledge base and successfully preparing them for language exams has become more important. The structure and content of modern business language exams reflect the need to meet the demands of the labour market. There has been a definite shift from grammar-oriented, translation-based tasks towards a more communicative approach which involves testing reading comprehension, writing skills and performance in situational role plays. However, while students generally cope well with understanding written business texts, many of them frequently fail in oral communication. Consequently, the question arises of whether it is possible to bridge the obvious gap between reading and speaking skills. This paper aims to give a possible example of how a descriptive text can be adapted to prepare students for the situational role play tasks in business language exams at the Faculty of Economics and Business Administration, University of Debrecen

  3. 77 FR 20822 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-06

    ... in response to ``Identifying Modifiable Protective Factors for Intimate Partner Violence or Sexual... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease... announced below concerns Identifying Modifiable Protective Factors for Intimate Partner Violence or Sexual...

  4. Human development and South East Asian countries: Special emphasis on India

    OpenAIRE

    Sharma, Kalpa

    2013-01-01

    ?Development? is to improve the quality of people's lives by creating an environment for them to engage in a wide range of activities, to be healthy and well nourished, to be knowledgeable and to be able to participate in the community life. The Human Development Index (HDI) is a multi-dimensional index of development as it is the combination of three development indices- health index, education index and income index. This article attempts to compare the HDI and its components between variou...

  5. Safety and reliability of pressure components with special emphasis on advanced methods of NDT. Vol. 2

    International Nuclear Information System (INIS)

    1986-01-01

    The 12 papers discuss topics of strength and safety in the field of materials technology and engineering. Conclusions for NPP component safety and materials are drawn. Measurements and studies relate to fracture mechanics methods (oscillation, burst, material strength, characteristics). The dynamic analysis of the behaviour of large test specimens, the influence of load velocity on crack resistance curve and the development of forged parts from austenitic steel for fast breeder reactors are presented. (DG) [de

  6. Epidemiology of elephantiasis with special emphasis on podoconiosis in Ethiopia: A literature review.

    Science.gov (United States)

    Yimer, Mulat; Hailu, Tadesse; Mulu, Wondemagegn; Abera, Bayeh

    2015-06-01

    Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts. Some conditions having this symptom include: Elephantiasis nostras, due to longstanding chronic lymphangitis; Elephantiasis tropica or lymphatic filariasis, caused by a number of parasitic worms, particularly Wuchereria bancrofti; non-filarial elephantiasis or podoconiosis, an immune disease caused by heavy metals affecting the lymph vessels; proteus syndrome, the genetic disorder of the so-called Elephant Man, etc. Podoconiosis is a type of lower limb tropical elephantiasis distinct from lymphatic filariasis. Lymphatic filariasis affects all population at risk, whereas podoconiosis predominantly affects barefoot subsistence farmers in areas with red volcanic soil. Ethiopia is one of the countries with the highest number of podoconiosis patients since many people are at risk to red-clay soil exposure in many parts of the country. The aim of this review was to know the current status and impact of podoconiosis and its relevance to elephantiasis in Ethiopia. To know the epidemiology and disease burden, the literatures published by different scholars were systematically reviewed. The distribution of the disease and knowledge about filarial elephantiasis and podoconiosis are not well known in Ethiopia. It is relatively well studied in southern Ethiopia but data from other parts of the country are limited. Moreover, programmes that focus on diagnosis, treatment, prevention and control of filarial elephantiasis and podoconiosis are also non-existent even in endemic areas. Furthermore, the disease mapping has not been carried out country-wide. Therefore, in order to address these gaps, Ethiopian Ministry of Health needs to take initiative for undertaking concrete research and mapping of the disease in collaboration with stakeholders.

  7. A comparison of three different pension savings products with special emphasis on the payout phase

    DEFF Research Database (Denmark)

    Jørgensen, Peter Løchte; Linnemann, Per

    2012-01-01

    The purpose of this article is to illustrate how the pension benefits a pension saver will (expect to) receive will depend on the type of pension scheme chosen. We compare three widely different pension savings products: the ‘‘traditional’’ with-profits scheme involving bonus entitlement (average...

  8. 76 FR 28438 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2011-05-17

    ... announced below concerns ``Affordable Care Act (ACA): Childhood Obesity Research Funding Opportunity..., discussion, and evaluation of ``Affordable Care Act (ACA): Childhood Obesity Research Funding Opportunity... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease...

  9. 76 FR 28790 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review.

    Science.gov (United States)

    2011-05-18

    ... announced below concerns Affordable Care Act (ACA): Childhood Obesity Research Funding Opportunity... ``Affordable Care Act (ACA): Childhood Obesity Research Funding Opportunity Announcement (FOA) DP11-007, Panel... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease...

  10. Early Childhood Intervention Partnerships on the Navajo Reservation with an Emphasis on Special Education.

    Science.gov (United States)

    Sealander, Karen; Medina, Catherine; Gamble, Armanda; Pettigrew, Bobbie; Snyder, Maria; White, Sherri; Begay, Mary Helen; Bradley, Brian; Bradley-Wilkinson, Evangeline; Heimbecker, Connie; McCarty, Nellie; Nelson, Bernita; Nelson, Jacob; Smith, Jody; Whitehair, Marsha; Redsteer, Denise; Prater, Greg

    Kayenta Unified School District (KUSD) is located in the Navajo Reservation in Arizona. In addition to serving over 2,600 K-12 students, KUSD collaborates with the Navajo Nation and the Kayenta community to provide three early childhood education programs: Acceptance Belonging Caring (ABC) preschool, Navajo Nation Head Start, and Child Care…

  11. Overview on Techniques to Construct Tissue Arrays with Special Emphasis on Tissue Microarrays

    Science.gov (United States)

    Vogel, Ulrich

    2014-01-01

    With the advent of new histopathological staining techniques (histochemistry, immunohistochemistry, in situ hybridization) and the discovery of thousands of new genes, mRNA, and proteins by molecular biology, the need grew for a technique to compare many different cells or tissues on one slide in a cost effective manner and with the possibility to easily track the identity of each specimen: the tissue array (TA). Basically, a TA consists of at least two different specimens per slide. TAs differ in the kind of specimens, the number of specimens installed, the dimension of the specimens, the arrangement of the specimens, the embedding medium, the technique to prepare the specimens to be installed, and the technique to construct the TA itself. A TA can be constructed by arranging the tissue specimens in a mold and subsequently pouring the mold with the embedding medium of choice. In contrast, preformed so-called recipient blocks consisting of the embedding medium of choice have punched, drilled, or poured holes of different diameters and distances in which the cells or tissue biopsies will be deployed manually, semi-automatically, or automatically. The costs of constructing a TA differ from a few to thousands of Euros depending on the technique/equipment used. Remarkably high quality TAs can be also achieved by low cost techniques. PMID:27600339

  12. Proper housing conditions in experimental stroke studies – special emphasis on environmental enrichment

    Directory of Open Access Journals (Sweden)

    Satu eMering

    2015-03-01

    Full Text Available Environmental enrichment provides laboratory animals with novelty and extra space, allowing different forms of multisensory stimulation ranging from social grouping to enhanced motor activity. At the extreme end of the spectrum, one can have a super-enriched environment. Environmental enrichment is believed to result in improved cognitive and sensorimotor functions both in naïve rodents and in animals with brain lesions such as those occurring after a stroke. Robust behavioral effects in animals which have suffered a stroke are probably related not only to neuronal plasticity in the perilesional cortex but also in remote brain areas. There is emerging evidence to suggest that testing restorative therapies in an enriched environment can maximize treatment effects, e.g., the perilesional milieu seems to be more receptive to concomitant pharmacotherapy and/or cell therapy. This review provides an updated overview on the effect of an enriched environment in stroke animals from the practical points to be considered when planning experiments to the mechanisms explaining why combined therapies can contribute to behavioral improvement in a synergistic manner.

  13. 77 FR 2548 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

    Science.gov (United States)

    2012-01-18

    ... 21-22, 2012 (Closed). Place: Crowne Plaza Atlanta Perimeter Hotel at Ravinia, 4355 Ashford Dunwoody... Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463...

  14. 75 FR 46952 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): National...

    Science.gov (United States)

    2010-08-04

    ...., September 20, 2010 (Closed). 8 a.m.-5 p.m., September 21, 2010 (Closed). Place: Sheraton Gateway Hotel..., pursuant to Public Law 92-463. Matters To Be Discussed: The meeting will include the initial review...

  15. 76 FR 13414 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Evaluation...

    Science.gov (United States)

    2011-03-11

    ... aforementioned meeting: Time and Date: 8 a.m.-5 p.m., May 2, 2011 (Closed). Place: Sheraton Gateway Hotel Atlanta..., pursuant to Public Law 92-463. Matters to be Discussed: The meeting will include the initial review...

  16. 77 FR 25485 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-04-30

    ... Terrace Hotel, 659 Peachtree Street NE., Atlanta Georgia 30308. Status: The meeting will be closed to the... Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463...

  17. 76 FR 5379 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Science.gov (United States)

    2011-01-31

    ... Terrace Hotel, 659 Peachtree Street, NE., Atlanta, GA 30308, Telephone: (404) 898-8305. Status: The..., pursuant to Public Law 92-463. Matters To Be Discussed: The meeting will include the initial review...

  18. 75 FR 22816 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Revitalizing Core...

    Science.gov (United States)

    2010-04-30

    ... (Closed). Place: JW Marriott Hotel Buckhead, 3300 Lenox Road, Atlanta, GA 30326, Telephone (404) 262-3344... Services Office, CDC, pursuant to Section 10(d) of Public Law 92-463. Matters To Be Discussed: The meeting...

  19. 77 FR 291 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2012-01-04

    ... Date: 8 a.m.-5 p.m., February 28, 2012 (Closed). Place: Sheraton Gateway Hotel Atlanta Airport, 1900... Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463...

  20. 76 FR 15984 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Science.gov (United States)

    2011-03-22

    ... aforementioned meeting: Time and Date: 8 a.m.-5 p.m., May 3, 2011 (Closed). Place: Sheraton Gateway Hotel Atlanta..., pursuant to Public Law 92-463. Matters To Be Discussed: The meeting will include the initial review...

  1. 77 FR 2549 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

    Science.gov (United States)

    2012-01-18

    ... 21-22, 2012 (Closed). Place: Crowne Plaza Atlanta Perimeter Hotel at Ravinia, 4355 Ashford Dunwoody... Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463...

  2. 75 FR 21339 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Developing...

    Science.gov (United States)

    2010-04-23

    ... meeting: Time and Date: 8 a.m.-5 p.m., May 18, 2010 (Closed). Place: Sheraton Gateway Hotel Atlanta... Public Law 92-463. Matters to be Discussed: The meeting will include the initial review, discussion, and...

  3. 76 FR 7217 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Enhanced...

    Science.gov (United States)

    2011-02-09

    ...., March 21, 2011 (Closed). Place: Sheraton Gateway Hotel Atlanta Airport, 1900 Sullivan Road, Atlanta... Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463. Matters To Be...

  4. 76 FR 367 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV...

    Science.gov (United States)

    2011-01-04

    ...) Place: Sheraton Gateway Hotel Atlanta Airport, 1900 Sullivan Road, Atlanta, Georgia 30337, Telephone... Analysis and Services Office, CDC, pursuant to Public Law 92-463. Matters to be Discussed: The meeting will...

  5. 76 FR 12361 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Determine of...

    Science.gov (United States)

    2011-03-07

    ... aforementioned meeting: Time and Date: 8 a.m.-5 p.m., May 2, 2011 (Closed). Place: Sheraton Gateway Hotel Atlanta..., pursuant to Public Law 92-463. Matters To Be Discussed: [The meeting will include the initial review...

  6. Computer simulations of atomic collisions in solids with special emphasis on sputtering

    International Nuclear Information System (INIS)

    Andersen, H.H.

    1986-01-01

    Computer simulations of atomic collisions in solids are traditionally divided into fully interacting or molecular dynamics (MD) simulations on the one side and simulations based on the binary collision approximation (BCA) on the other. The historical development of both branches is followed and other dichotomies viz. between static and dynamic target models and between models using crystalline and amorphous targets are introduced. The influence of the main input parameters, viz. interatomic potentials, surface- and bulk-binding energies and inelasticity is discussed before selected results are treated. Here, results for non-linear effects, clusters, fluctuations and for angular distributions are presented. The review is concluded with a discussion of the influence of computer developments on future simulations. With 392 refs

  7. Human development and South East Asian countries: Special emphasis on India.

    Science.gov (United States)

    Sharma, Kalpa

    2013-08-31

    'Development' is to improve the quality of people's lives by creating an environment for them to engage in a wide range of activities, to be healthy and well nourished, to be knowledgeable and to be able to participate in the community life. The Human Development Index (HDI) is a multi-dimensional index of development as it is the combination of three development indices- health index, education index and income index. This article attempts to compare the HDI and its components between various South East Asian countries. Secondary data is used. India's position on the HDI scale is equivalent to the South East Asian average and rank 134 out of more than 190 countries. In South East Asia, India stood fifth in HDI, behind Sri Lanka, Thailand, Maldives and Indonesia. Country has launched several schemes and programs to improve the health indicators, to provide elementary education to every child and to alleviate poverty. India's HDI value has improved with time but still country has a long way to go in achieving an acceptable HDI. Need is to strengthen the existing schemes and programs.

  8. Bioequivalence study of two losartan tablet formulations with special emphasis on cardiac safety.

    Science.gov (United States)

    Khandave, Suhas S; Sawant, Satish V; Sahane, Rakhi V; Murthi, Vivekanand; Dhanure, Shivanand S; Surve, Pradeep G

    2012-05-01

    To study the bioequivalence of Losartan Potassium Tablets 50 mg manufactured by Micro Labs Ltd. India to Cozaar® Tablets 50 mg, manufactured by Merck Sharp and Dohme Ltd., UK in normal healthy adult subjects under fasting condition along with the comparative safety evaluation of both treatments. The in vitro dissolution studies were carried out on 12 units each of test and reference products using the paddle method and dissolution media like water, 0.1 N hydrochloric acid with pH 1.2, pH 4.5 acetate buffer and pH 6.8 phosphate buffer. An open label, randomized, two-treatment, two-period, two-sequence, crossover bioequivalence study with a washout period of 7 days was conducted in 60 healthy Indian male subjects. Serial blood samples were collected after drug administration in each study period. Plasma concentrations of losartan and losartan acid were determined using a validated LC-MS-MS method. The pharmacokinetic parameters of losartan and losartan acid were determined using a non compartmental model. Occurrence of adverse events, change in systolic blood pressure, diastolic blood pressure, heart rate and QT interval from the baseline to 3.50 h post dose were studied and compared between the two treatments as safety parameters. The in vitro study proved the essential similarity of both the formulations as evident from the similarity factor of > 50% in all the dissolution media. The ratios for geometric least square means and 90% confidence intervals were within the acceptance criteria of 80% to 125% for log transformed C(max), AUC(0-t) and AUC(0-∞) for losartan. No statistically significant difference between the two treatments was observed for either of the safety parameters. The test product Losartan Potassium tablets 50 mg manufactured by Micro Labs Limited, India was bioequivalent to Cozaar® tablets 50 mg, manufactured by Merck Sharp and Dohme Ltd., UK in terms of rate and extent of absorption. Both treatments were well tolerated and had similar non significant effect on the safety parameters.

  9. Patient dose management practice in computed tomography with special emphasis to pediatric patients

    International Nuclear Information System (INIS)

    Kharita, M. H.; Wali, Kh.

    2010-12-01

    As per UNSCEAR 2000, CT contributes over 34% of collective dose from diagnostic X-Ray examinations in the world. The radiation dose in CT particular importance for children, it is very well known that children are more sensitive and likely to get radiation induced cancer than adults. This paper discusses the radiation dose of patients (adults and children) in Computed Tomography in syria ( 30 CT units form 6 different manufacturers). The radiation dose measurements has covered computed tomography dose index, dose length product and effective dose. The result of this study indicating, that most computed tomography dose index and dose length product values recorded were below dose reference levels, only for high resolution chest protocol, the dose length product results were higher than that of the International Commission on Radiological Protection (author)

  10. Health effects of UV-B exposure; with special emphasis on the immune system

    NARCIS (Netherlands)

    Goettsch W; Garssen J; de Gruijl FR; van Loveren H

    1992-01-01

    As a results of a depletion of atmospheric ozone all living organisms on the earth"s surface may be exposed to increased amounts of ultraviolet radiation. In man, ultraviolet radiation (UVR, especially UV-B) can cause, in addition to some beneficial effects like vitaming D formation,

  11. Patient doses in CT with special emphasis on pediatric patients in Algeria

    International Nuclear Information System (INIS)

    Khelassi-Toutaoui, Nadia; Merad, Ahmed; Toutaoui, Aek; Bairi, Souad; Tsapaki, Virginia; Mansouri, Boudjema

    2008-01-01

    Full text: Purpose: To estimate the frequency of CT examinations in children 0-15 years of age, to investigate whether exposure factors for children are different than for adults and to evaluate patient dose, as part of an International Atomic Energy Agency (IAEA) project on Radiation Protection of patients and Medical Exposure Control (RAF 9033). Material and Methods: Two CT machines were included in the study. Weighted computed tomography dose index (CTDI w ). Results: Pediatric CT examinations accoutered for 12-20% of the total exams performed in the CT facilities. For head, chest and abdomen examinations, mAs were reduced for pediatric patients, mainly on an arbitrary manner. One of the CT machines allowed change of kV and in that case kV was reduced for pediatric patients. Chest, Chest-High Resolution, Abdomen, Lumbar spine and Pelvis CTDI w and DLP were lower and IAEA guidance levels in almost all types of exams. It was observed, however, that DLP in one hospital was almost double than the other hospital that was mostly attributed to larger extent of scan length. ) for a single slice and dose length product (DLP) for a complete examination were used to evaluate patient dose. Kilovoltage (kV) and mAs were the exposure factors investigated. Conclusion: The study showed that pediatric examinations reach up to 1/5 of the total exams performed. It is encouraging that exposure factors are reduced, but a more standard method of reduction should be applied. Patient doses were lower that IAEA standards. Further optimization could be done by reducing scan length. (author)

  12. Characterization of groundwater composition in Punjab state with special emphasis on uranium content, speciation and mobility

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Ajay; Rout, Sabyasachi; Mishra, Manish K.; Ravi, P.M. [Bhabha Atomic Reseach Centre, Mumbai (India). Health Physics Div.; Tripathi, R.M. [Bhabha Atomic Reseach Centre, Mumbai (India). Environmental Assessment Div.; Ghosh, A.K. [Bhabha Atomic Reseach Centre, Mumbai (India). Health, Safety and Environmental Group

    2014-04-01

    Groundwaters (borewell and handpump) were sampled from two districts (Bathinda and Mansa) of Punjab state and analyzed for their major ionic concentrations and uranium isotope compositions in order to assess the possible origins of the waters and water-rock interactions that occurred in the deep aquifer system. The major ionic concentrations of waters were plotted on a Piper diagram and grouped into four dominant hydrochemical facies as (Na+K)-SO{sub 4}+Cl type (69%-73%), (Ca+Mg)-SO{sub 4}+Cl type (6% - 21%), (Ca+Mg)-HCO{sub 3} type (4% - 6%) and (Na+K)-HCO{sub 3} type (2% - 19%). It was observed that mobility of uranium in groundwater was very much influenced by TDS (total dissolved solids). To investigate the various mechanisms for deriving the elevated uranium concentrations in groundwater, {sup 234}U/{sup 238}U activity ratios (ARs) were calculated using the determined activity levels of {sup 234}U and {sup 238}U. The mean ARs was found to be near unity (i.e. secular equilibrium) in the study regions confirmed that uranium in groundwaters was mainly resulted from its host/parent rocks through weathering processes. The concentration of HCO{sub 3}{sup -} in ground water showed one order of magnitude higher than the total dissolved SiO{sub 2} indicates that carbonate weathering was the dominant process due to major water-rock interaction. The uranium speciation in groundwaters was investigated by an equilibrium model calculation using MEDUSA (make equilibrium diagrams using sophisticated algorithms) under the influence of redox conditions and complexant concentration. At the observed range of pH values, the predominant redox speciation of uranium was observed as hydroxo-carbonato complexes of (UO{sub 2}){sub 2}(CO{sub 3})(OH){sub 3}{sup -} and hydroxyl complexes of UO{sub 2}(OH){sub 3}{sup -} which might be caused for increasing the solubility of uranium. Due to very low concentration of phosphate in groundwater, its effects on U(VI)-aqueous speciation was negligible. (orig.)

  13. Lyssaviruses: special emphasis on rabies virus and other members of the lyssavirus genus.

    Science.gov (United States)

    Harkess, Graeme; Fooks, Anthony R

    2011-01-01

    Rabies is routinely diagnosed based on the clinical description and history of exposure in a rabies-endemic country. A negative diagnostic test for rabies virus or a related lyssavirus does not exclude the clinical diagnosis. Diagnostic tests are never optimal and are entirely dependent on the nature and quality of the sample supplied. Often, only a sample from a single time point is investigated reducing the overall sensitivity of any diagnosis. With the advent of molecular biology, tests have been developed that are rapid, robust, and sensitive in support of the rapid detection and strain identification of rabies virus from clinical specimens. These molecular tests complement conventional tests in rabies diagnosis, particularly for human cases, for which an early laboratory diagnosis is critical and may decrease the number of unnecessary contacts with the patient, reduce the requirement for invasive and costly interventions, and enable the appropriate medical treatment regimen to be administered for the patient. The barrier to success is in transferring the technology for the latest techniques in rabies diagnosis to rabies-endemic countries. These barriers are not insurmountable and in liaison with international organisations, especially OIE, FAO, and WHO, these diagnostic tests will be validated for rabies diagnosis and surveillance, and implemented in modern and well-equipped diagnostic laboratories throughout the world.

  14. Management value of the brand with special emphasis on the emotional aspect of branding

    Directory of Open Access Journals (Sweden)

    Marinković Vladimir

    2015-01-01

    Full Text Available Turbulent of markets, which in future will be more dynamic, based on close collaboration companies (brands with towards his customers. Having a prestigious brand and loyal customers is the goal of which tend to all market participants. However, many companies are not able to predict and plan the management of the brand, but remain on a superficial understanding of branding as a simple process of creating names, slogans and product design. If brands fail to achieve an emotional connection with the customer, then the way to achieve business success and profit maximizing open. An increasing number of companies realize the importance and necessity of branding. Realizing that a good reputation and positive image reflected in business success, the company recently increasingly pay attention to this issue.

  15. 78 FR 60878 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-10-02

    ... announced below concerns National Center for Construction Safety and Health Research and Translation (U60..., 2013 (Closed); 8 a.m.-12 p.m., November 21, 2013 (Closed). Place: Embassy Suites Alexandria Hotel, 1900... evaluation of applications received in response to ``National Center for Construction Safety and Health...

  16. Pathophysiology of GPCR Homo- and Heterodimerization: Special Emphasis on Somatostatin Receptors

    Directory of Open Access Journals (Sweden)

    Rishi K. Somvanshi

    2012-04-01

    Full Text Available G-protein coupled receptors (GPCRs are cell surface proteins responsible for translating >80% of extracellular reception to intracellular signals. The extracellular information in the form of neurotransmitters, peptides, ions, odorants etc is converted to intracellular signals via a wide variety of effector molecules activating distinct downstream signaling pathways. All GPCRs share common structural features including an extracellular N-terminal, seven-transmembrane domains (TMs linked by extracellular/intracellular loops and the C-terminal tail. Recent studies have shown that most GPCRs function as dimers (homo- and/or heterodimers or even higher order of oligomers. Protein-protein interaction among GPCRs and other receptor proteins play a critical role in the modulation of receptor pharmacology and functions. Although ~50% of the current drugs available in the market target GPCRs, still many GPCRs remain unexplored as potential therapeutic targets, opening immense possibility to discover the role of GPCRs in pathophysiological conditions. This review explores the existing information and future possibilities of GPCRs as tools in clinical pharmacology and is specifically focused for the role of somatostatin receptors (SSTRs in pathophysiology of diseases and as the potential candidate for drug discovery.

  17. Probiotics, with special emphasis on their role in the management of ...

    African Journals Online (AJOL)

    2010-12-19

    Dec 19, 2010 ... The gut microbiota comprises a complex ecological system, consisting of at least 500 ... microbiota plays a key role in the development of immune processes and protection against ... with obesity,17,18. Crohn's disease ...

  18. History on the biological nitrogen fixation research in graminaceous plants: special emphasis on the Brazilian experience

    Directory of Open Access Journals (Sweden)

    José I. Baldani

    2005-09-01

    Full Text Available This review covers the history on Biological Nitrogen Fixation (BNF in Graminaceous plants grown in Brazil, and describes research progress made over the last 40 years, most of whichwas coordinated by Johanna Döbereiner. One notable accomplishment during this period was the discovery of several nitrogen-fixing bacteria such as the rhizospheric (Beijerinckia fluminensis and Azotobacter paspali, associative (Azospirillum lipoferum, A. brasilense, A. amazonense and the endophytic (Herbaspirillum seropedicae, H. rubrisubalbicans, Gluconacetobacter diazotrophicus, Burkholderia brasilensis and B. tropica. The role of these diazotrophs in association with grasses, mainly with cereal plants, has been studied and a lot of progress has been achieved in the ecological, physiological, biochemical, and genetic aspects. The mechanisms of colonization and infection of the plant tissues are better understood, and the BNF contribution to the soil/plant system has been determined. Inoculation studies with diazotrophs showed that endophytic bacteria have a much higher BNF contribution potential than associative diazotrophs. In addition, it was found that the plant genotype influences the plant/bacteria association. Recent data suggest that more studies should be conducted on the endophytic association to strengthen the BNF potential. The ongoing genome sequencing programs: RIOGENE (Gluconacetobacter diazotrophicus and GENOPAR (Herbaspirillum seropedicae reflect the commitment to the BNF study in Brazil and should allow the country to continue in the forefront of research related to the BNF process in Graminaceous plants.A presente revisão aborda a história da Fixação Biológica de Nitrogênio (FBN em Gramíneas no Brasil, procurando mostrar a evolução da pesquisa na área iniciada a mais de 40 anos sob a liderança da pesquisadora Johanna Döbereiner. Um aspecto marcante deste período foi a descoberta de diversas bactérias fixadoras de nitrogênio atmosférico tais com as rizosféricas (Beijerinckia fluminensis e Azotobacter paspali, associativas (Azospirillum lipoferum, A. brasilense, A. amazonense e as endofíticas (Herbaspirillum seropedicae, H. rubrisubalbicans, Gluconacetobacter diazotrophicus, Burkholderia brasilensis e B. tropica. O papel destas bactérias diazotróficas em associação com as gramíneas, especialmente os cereais, tem sido estudado e muito se avançou sobre os aspectos ecológicos, fisiológicos, bioquímicos e genéticos. Os mecanismos de colonização e infecção dos tecidos das plantas foram melhor entendidos e a contribuição da FBN para o sistema solo-planta foi determinado. Estudos de inoculação de cereais com bactérias diazotróficas, têm mostrado que as endofíticas têm um maior potencial de contribuição da FBN e que o genótipo da planta influencia na associação da planta/bactéria. Os avanços alcançados apontam para uma maior exploração e entendimento desta associação endofítica. Os programas de sequenciamento do genoma: RIOGENE (Gluconacetobacter diazotrophicus e GENOPAR (Herbaspirillum seropedicae mostram a importância da FBN no Brasil e devem permitir que o país continue na fronteira do conhecimento em relação ao processo de FBN em gramíneas.

  19. Introduction of Eucalyptus spp. into the United States with Special Emphasis on the Southern United States

    Directory of Open Access Journals (Sweden)

    R. C. Kellison

    2013-01-01

    Full Text Available Introduction of Eucalyptus spp. into the United States from Australia on a significant scale resulted from the gold rush into California in 1849. Numerous species were evaluated for fuel, wood products, and amenity purposes. The first recorded entry of eucalyptus into the southern United Stated was in 1878. Subsequent performance of selected species for ornamental purposes caused forest industry to visualize plantations for fiber production. That interest led the Florida Forestry Foundation to initiate species-introduction trials in 1959. The results were sufficiently promising that a contingent of forest products companies formed a cooperative to work with the USDA Forest Service, Lehigh Acres, FL, USA, on genetic improvement of selected species for fiber production. The Florida initiative caused other industrial forestry companies in the upper South to establish plantations regardless of the species or seed source. The result was invariably the same: failure. Bruce Zobel, Professor of Forestry, North Carolina State University, initiated a concerted effort to assess the potential worth of eucalyptus for plantation use. The joint industrial effort evaluated 569 sources representing 103 species over a 14-year period. The three levels of testing, screening, in-depth, and semioperational trials led to identification of some species and sources that offered promise for adaptation, but severe winter temperatures in late 1983 and early 1984 and 1985 terminated the project. Despite the failed attempt valuable silvicultural practices were ascertained that will be beneficial to other researchers and practitioners when attempts are again made to introduce the species complex into the US South.

  20. Synovial sarcoma with relevant immunocytochemistry and special emphasis on the monophasic fibrous variant

    Directory of Open Access Journals (Sweden)

    Kottu Radhika

    2010-01-01

    Full Text Available Background: Monophasic fibrous synovial sarcoma (SS is the most common variant of SS. Only a few cytological studies are available on this entity. Bcl-2 protein expression has been described as a characteristic marker of SS and is useful for its differentiation from other sarcomas. Cytokeratin and CD99 are also used in detecting SS. Aims: To evaluate synovial sarcoma and its variants cytomorphologically. Materials and Methods: During a period of 10 years 7 months, i.e. from January 1998 to July 2008, 12 cytologic specimens diagnosed as synovial sarcoma were reviewed. Ten cases were diagnosed as SS on aspiration alone but two cases required ancillary technique i.e., immunocytochemistry staining with bcl-2 and cytokeratin. The smears were stained with Papanicolaou and May-Grόnwald-Giemsa stains. Results: All cytologic specimens in our study had similar appearance. Most smears were highly cellular and were made up of densely packed tri-dimensional groups and singly scattered round to oval cells. Cellular monomorphism and vascular channels within the cell groups were the remarkable findings. Only one case showed cytologic evidence of epithelial differentiation. Bcl-2, cytokeratin, CD99 positivity was seen on immunohistochemistry staining. Results were categorized according to age, sex and morphologic variants. Conclusions: Although cytomorphologic features of synovial sarcomas are characteristic enough to permit its recognition, clinical correlation is necessary for accurate diagnosis. Monophasic variant is the most common entity observed in the present study.

  1. Anaerobic digestion of fish processing wastewater with special emphasis on hydrolysis of suspendend solids

    NARCIS (Netherlands)

    Palenzuela Rollon, A.

    1999-01-01

    Fish processing industries comprise an important segment of the Philippine economy. However, among other industries, they pollute lakes, rivers, and eventually, coastal waters. If their effluents are not sufficiently treated, the well-being of the country's coastal waters is threatened. In

  2. Emerging functions of multi-protein complex Mediator with special emphasis on plants.

    Science.gov (United States)

    Malik, Naveen; Agarwal, Pinky; Tyagi, Akhilesh

    2017-10-01

    Mediator is a multi-subunit protein complex which is involved in transcriptional regulation in yeast and other eukaryotes. As a co-activator, it connects information from transcriptional activators/repressors to transcriptional machinery including RNA polymerase II and general transcription factors. It is not only involved in transcription initiation but also has important roles to play in transcription elongation and termination. Functional attributes of different Mediator subunits have been largely defined in yeast and mammalian systems earlier, while such studies in plants have gained momentum recently. Mediator regulates various processes related to plant development and is also involved in biotic and abiotic stress response. Thus, plant Mediator, like yeast and mammalian Mediator complex, is indispensable for plant growth and survival. Interaction of its multiple subunits with other regulatory proteins and their ectopic expression or knockdown in model plant like Arabidopsis and certain crop plants are paving the way to biochemical analysis and unravel molecular mechanisms of action of Mediator in plants.

  3. Fatty Acid Composition of Meat from Ruminants, with Special Emphasis on trans Fatty Acids

    DEFF Research Database (Denmark)

    Leth, Torben; Ovesen, L.; Hansen, K.

    1998-01-01

    The fatty acid composition was determined in 39 samples of beef, 20 samples of veal, and 34 samples of lamb, representative of the supply of ruminant meat in Denmark. Five cuts of beef and veal and three cuts of lamb with increasing fat content were selected, and analysis of the fatty acid methyl...... esters was performed by gas-liquid chromatography (GLC) on a polar 50-m capillary column CP Sil 88 with flame-ionization detection. Lamb had the highest content of saturated fatty acids (52.8 +/- 1.8 g/100 g fatty acids), higher than beef and veal (45.3 +/- 3.1 and 45.4 +/- 0.8 g/100 g fatty acids......, respectively). Cis monounsaturated fatty acids were 49.2 +/- 3.1, 44.9 +/- 1.8, and 37.7 +/- 1.7, and polyunsaturated fatty acids were 3.3 +/- 0.7, 5.8 +/- 2.0, and 5.0 +/- 0.1 g/100 g fatty acids in beef, veal, and lamb, respectively. Beef contained 2.1 +/- 0.8 g trans C-18:1 per 100 g fatty acids, about half...

  4. Bioavailability of heavy metals for the deposit feeder Macoma balthica with special emphasis on copper

    NARCIS (Netherlands)

    Absil, M.C.P.

    1993-01-01

    In coastal and estuarine regions of Western Europe, concentrations of contaminants in the sediment are often relatively high compared to the waterphase. Consequently, these contaminants might form a serious threat to animals living in and associated with the sediment.

    As a

  5. 76 FR 4702 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Cooperative...

    Science.gov (United States)

    2011-01-26

    ... the National Academic Centers of Excellence in Youth Violence Prevention (U01), Funding Opportunity... Centers of Excellence in Youth Violence Prevention (U01), FOA CE10-004, initial review''. Agenda items are... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease...

  6. Recent advances in protein and Peptide drug delivery: a special emphasis on polymeric nanoparticles.

    Science.gov (United States)

    Patel, Ashaben; Patel, Mitesh; Yang, Xiaoyan; Mitra, Ashim K

    2014-01-01

    Proteins and peptides are widely indicated in many diseased states. Parenteral route is the most commonly em- ployed method of administration for therapeutic proteins and peptides. However, requirement of frequent injections due to short in vivo half-life results in poor patient compliance. Non-invasive drug delivery routes such as nasal, transdermal, pulmonary, and oral offer several advantages over parenteral administration. Intrinsic physicochemical properties and low permeability across biological membrane limit protein delivery via non-invasive routes. One of the strategies to improve protein and peptide absorption is by delivering through nanostructured delivery carriers. Among nanocarriers, polymeric nanoparticles (NPs) have demonstrated significant advantages over other delivery systems. This article summarizes the application of polymeric NPs for protein and peptide drug delivery following oral, nasal, pulmonary, parenteral, transder mal, and ocular administrations.

  7. Side effects in preventive maintenance therapy with neuroleptics with special emphasis on tardive dyskinesia.

    Science.gov (United States)

    Logothetis, J; Paraschos, A; Frangos, E

    1981-01-01

    Neuroleptics induce hypersensitivity reactions, and toxic, systemic and extrapyramidal manifestations. The latter mainly include acute dystonic reactions, other early dyskinesias, akathisia, parkinsonism and TD. These drugs have been implicated for DA antagonism exerted by an adenylate cyclase inhibition. Prolonged blockade of DA receptors is considered as the motivation for a counterbalancing mechanism inducing the DA supersensitivity from which TD results. Recent reports suggest cholinergic and GABA ergic insufficiency as secondary participants. The increasing frequency of TD calls for prevention by modifying treatment practices and searching for effective measures to combat the symptoms.

  8. High power spatial filter considerations, with special emphasis on the cyclops geometry

    International Nuclear Information System (INIS)

    Simmons, W.W.; Guch, S.

    1974-01-01

    This document presents considerations leading to location and first-cut design of a lens-pinhole-lens spatial filter for Cyclops laser chain. Small scale beam break-up is the driving phenomenon for spatial filtering, and design is predicated upon estimates of this effect's magnitude. The departure of the beam from diffraction limited performance (due to astigmatism and to whole beam self-focusing) is presented in terms of pinhole size limitations. All calculations are presented in terms of parameters associated with Cyclops, through the B stages, assuming that the spatial filter is located at this point in the chain, and that the focal length of the input spatial filter lens is 100 cm. The geometrical ray diagram is shown

  9. Atmospheric chemistry of polycyclic aromatic compounds with special emphasis on nitro derivatives

    Energy Technology Data Exchange (ETDEWEB)

    Feilberg, A.

    2000-04-01

    Field measurements of polycyclic aromatic compounds (PAC) have been carried out at a semi-rural site and at an urban site. Correlation analyses, PAC indicators, and PAC ratios have been used to evaluate the importance of various sources of nitro-PAHs. A major source of nitro-PAHs is atmospheric transformation of PAHs initiated by OH radicals. Especially during long-range transport (LRT) of air pollution from Central Europe, the nitro-PAH composition in Denmark is dominated by nitro-PAHs formed in the atmosphere. Locally emitted nitro-PAHs are primarily from diesel vehicles. Levels of unsubstituted PAHs can also be strongly elevated in connection with LRT episodes. The ratio of 2-nitrofluoranthene relative to 1-nitropyrene is proposed as a measure of the relative photochemical age of particulate matter. Using this ratio, the relative mutagenicity of particle extracts appears to increase with increasing photochemical age. In connection with the field measurements, a method for measuring nitro-PAHs in particle extracts based on MS-MS detection has been developed. The atmospheric chemistry of nitronaphthalenes has been investigated with a smog chamber system combined with simulation with photochemical kinetics software. A methodology to implement gas-particle partitioning in a model based on chemical kinetics is described. Equilibrium constants (KP) for gas-particle partitioning of 1- and 2-nitronaphthalene have been determined. Mass transfer between the two phases appears to occur on a very short timescale. The gas phase photolysis of the nitronaphthalenes depends upon the molecular conformation. Significantly faster photolysis of 1-nitronaphthalene than of 2-nitronaphthalene is observed. The photochemistry of nitro-PAHs, and to some extent other PAC, associated with organic aerosols, has been studied with model systems simulating organic aerosol material. A number of aerosol constituents, including substituted phenols, benzaldehydes, and oxy-PAHs, are demonstrated to accelerate the photodegradation. The results are compared with smog chamber observations. The photodegradation of PAC is strongly dependent on the physical state of the organic medium. Viscosity, temperature, and water content are of importance for the degradation rates. Nitro-PAHs are photochemically reduced to amino-PAHs under conditions of low O2 concentrations and high polarity as demonstrated by using glycerine as a surrogate for the organic fraction of ambient aerosols. Pulse radiolysis experiments have shown that reactions with OH radicals in atmospheric water droplets represent an important sink for water soluble PAC. Rate constants for reactions of N-PAC with OH radicals and for the subsequent reactions of the OH-adducts with O2 have been determined. (au)

  10. 75 FR 28810 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing...

    Science.gov (United States)

    2010-05-24

    ... Diseases and Related Public Health Concerns in India, Funding Opportunity Announcement (FOA) GH10-002... Public Health Concerns in India,'' FOA GH10-002. Contact Person for More Information: Hylan D. Shoob, PhD, M.S.P.H., Scientific Review Officer, CDC, 1600 Clifton Road, NE., Mailstop D72, Atlanta, GA 30333...

  11. 78 FR 20319 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Science.gov (United States)

    2013-04-04

    ... and Kerala, India, FOA GH13- 003; Strengthening Surveillance for Japanese Encephalitis in India, FOA..., India, FOA GH13-003; Strengthening Surveillance for Japanese Encephalitis in India, FOA GH13-004..., Scientific Review Officer, CGH Science Office, Center for Global Health, CDC, 1600 Clifton Road, NE...

  12. Hydrodynamic modeling along the southern tip of India: A special emphasis on Kanyakumari coast

    Directory of Open Access Journals (Sweden)

    K. Gurumoorthi

    2017-12-01

    Full Text Available Hydrodynamic models are important to many coastal engineering designs and application, especially addressing sediment and water quality. In this study, MIKE 21 two-dimensional (2D hydrodynamic model based on the flexible mesh (FM technique was used to simulate the surface currents forced by tides and winds in Kanyakumari coast. The model results of the tidal level along shore and cross shore currents are agreed well with measured data in Kanyakumari coast. The major components of tides and currents are analyzed by harmonic analysis methods. Root mean square error (RMSE values for the measured and model tides (0.017 m and 0.079 m and currents (0.025 m/s and 0.009 m/s during the northeast (NE and southwest (SW monsoon period are calculated. A series of scenario runs for NE and SW monsoon season are used to understand the regional circulation. The model result shows that the Kanyakumari coast is dominated by tides and surface currents flow, which are influenced by the seasonal reversal wind pattern. Flows around this coastal water have been evidenced small scale cyclonic and anti-cyclonic eddies ranged from ∼55 to 120 km in diameter. The cyclonic and anti-cyclonic eddies are mostly appeared in near Kanyakumari and SE coast of Kerala due to local/ remotely generated forces.

  13. The pathogenesis of allergic rhinitis : cellular aspects with special emphasis on Langerhans cells

    NARCIS (Netherlands)

    W.J. Fokkens (Wytske)

    1991-01-01

    textabstractPresent ideas concerning the pathogenesis of allergic rhinitis are largely deduced from systemic investigations and extrapolated from studies in the skin and the lung. Studies on allergic rhinitis generally comprise clinical aspects and/or biochemical, humoral and cellular features of

  14. Emerging trends in forensic science with special emphasis on nuclear and radiochemistry

    International Nuclear Information System (INIS)

    Krishnamurthy, Rukmani

    2011-01-01

    Forensic science uses the basic principles of all physical and natural science and have evolved many domain of its owns, like Anthropometry, fingerprint, Foot print, ballistics, documentation, Forensic Biology and Serology, Forensic Chemistry, Nuclear forensic science, Forensic Physic, Toxicology, Odontology, Forensic DNA, Cyber Forensic, Forensic Psychology, Forensic engineering etc., which provides a fool prove scientific aid to criminal justice administration. Nuclear forensic science is a fairly young discipline and only a small number of laboratories are active practitioners. However, the number of incidents of illicit trafficking reported and furthermore, the threat of nuclear terrorism calls for preparedness and for effective tools providing hints on the origin of the material and thus on the perpetrator. The determination of characteristic parameters is subject to ongoing research and development work in a number of nuclear measurement laboratories. Parameters like isotopic composition, chemical impurities, age of the material, macroscopic parameters and microstructure provide clues on the origin and on the intended use of the material. Today, nuclear forensics has reached a high degree of maturity and it is highly relevant in the areas of non-proliferation and of nuclear security. Continued development activities and strengthened international cooperation will be of key importance for the perfection of the discipline of nuclear forensics

  15. Fate of induced mutations in higher plants with special emphasis on sexually reproducing species

    International Nuclear Information System (INIS)

    Cornu, Andre

    1978-01-01

    A mutation induced in a plant somatic cell has to overcome quite many difficulties before being isolated and utilized as a marker in a mutated line. If induced in a meristem, three conditions must be fulfilled for the mutation to be transmitted to the subsequent generation: it must be compatible with normal cell multiplication, it must be located in a cell mass that will provide an inflorescence, and it must be in the sporogenetic layer (t2). Under these conditions, or if it is induced in a gamete or in a zygote, the mutation enters a first cycle of sexual reproduction. Meiosis and the subsequent haploid phase constitute severe screening steps for many chromosome aberrations. Studies on Petunia performed by means of marker genes show that male and female gametic viabilities are drastically impaired by deletions. However, a deficient chromosome can be transmitted when the losss of information is compensated for by homologous information as, for example, diploid gametes from tetraploids or disomic gametes resulting from non-disjunction. If partial or complete sterility, whether sporo- or gametophytic, is avoided, then the mutation can be transmitted to the next generation in heterozygous state. When becoming homozygous, the mutation may have effects such that its use can be most difficult. This is the case when this mutation causes rather early lethality or severe sterility. Thus, in higher plants, one faces several cases of powerful and efficient selection against mutations. On the basis of experiments carried out on Petunia, the per locus mutation rate of practical interest ranges between I and 5/10000M 1 plants. Practical conclusions are drawn about which organ should be treated, which mutagen at what dose should be used according to the scope of the research undertaken [fr

  16. Water reactor fuel element fabrication, with special emphasis on its effects on fuel performance

    International Nuclear Information System (INIS)

    1979-01-01

    Full text: The performance of nuclear fuel has improved over the years and is now a minor cause of outages and of power limitations in nuclear power plants. On the other hand, an increasing number of countries are in the process of developing or implementing their own capability for manufacturing fuel elements. In this context, the IAEA International Working Group on Water Reactor Fuel Performance and Technology (IWGFPT) advised that a symposium be organized devoted to the relationship between fuel fabrication and performance The Czechoslovak Atomic Energy Commission agreed to co-operate in the organization of this symposium and to host it in Prague. Those factors which influence fuel fabrication requirements are now well ascertained: as little reactor primary circuit contamination as possible, the tendency to increased burnups, reactor manoeuverability to match power grid demands, the desirability of an autonomous fabrication capability. It is the general experience of fuel element suppliers that fuel quality and performance has increased over the years, the importance of quality assurance and process monitoring has been decisive in this respect The ever increasing mass-production aspect of nuclear fuel leads to some processing steps being revised and alternatives being developed. The relation between fabrication processes and fuel performance characteristics, although generally well perceived, are still the subject of a large amount of experiment and assessment in most countries, both industrial and developing This evidence is most encouraging; it means indeed that nuclear power, which is already amongst the cheapest and safest sources of energy, will continue to be improved. The performance of Zircaloy fuel cladding - presently the material used in most water reactors - is under particular consideration. Better understanding of this quite recent alloy will pave the way for broader fuel utilization limits in the future. The panel discussion, which noted some recent meetings in related fields and included a cost-benefit assessment, indicated that the trends identified at this meeting were part of a general observation, namely that fuel fabrication technology is in a position to meet today's performance requirements, but that it is worth while pursuing efforts to broaden fuel utilization limits and economy. As the Chairman of the IWGFPT indicated in his concluding remarks, the fact that no novel discovery had to be announced at the meeting is the best indication that nuclear fuel has really reached maturity and has become an industrial, rather than a scientific, product. Technological improvements however are still possible and are being implemented. The symposium proved a good opportunity to evaluate the present status of fuel fabrication in relation to its performance. (author)

  17. Recertification in allergy and immunology: an historical review with special emphasis on the 1983 examination.

    Science.gov (United States)

    Slavin, R G; Des Prez, L; Mansmann, H C; Meskauskas, J A; Pierson, W

    1985-03-01

    Recertification offers a method of evaluating a diplomate's cognitive knowledge of allergy and immunology. In 1983 candidates for the American Board of Allergy and Immunology recertification examination were offered the entire certifying examination but were informed that they would, for recertification purposes, be held responsible only for a subset of questions judged to be particularly clinically relevant. All 40 candidates elected to take the entire certifying examination. Differences between the performance of certifying and recertifying candidates on the recertifying questions were small. Except for the five-choice questions, the differences in performance between the two groups on the remaining questions were also small in an absolute sense. Recertification performance was not related to the time of original certification. Ninety-eight percent of the candidates completed a questionnaire after the examination. Ninety percent stated that they would encourage their colleagues to participate in the recertification process.

  18. 76 FR 9020 - Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel (SEP): Ability of...

    Science.gov (United States)

    2011-02-16

    ... Integrated Tick Management (ITM) Technologies To Reduce the Entomological Risk of Lyme Disease, Funding... Tick Management (ITM) Technologies To Reduce the Entomological Risk of Lyme Disease, FOA CK11-005...

  19. A Team Approach to Management by Objectives with Special Emphasis on Managerial Self-Evaluation.

    Science.gov (United States)

    Alvir, Howard P.

    This kit contains everything needed to explain, criticize and plan, simulate, and evaluate a management by objectives (MBO) program. The kit has been field tested in state agencies, schools, businesses, and volunteer organizations. Rather than present only the strengths of MBO, this program defines MBO, presents its strong points in discussing the…

  20. Models of Social Exploitation with Special Emphasis on Slovenc Traffic Economics

    Directory of Open Access Journals (Sweden)

    Iztok Ostan

    2005-01-01

    Full Text Available In order to decipher the organisational behaviour operatingin the transport sector of the economy it is necessary to discoverthe prevalent patterns of social exploitation at work. PreliminaJyresults of a study of experienced irregular traffic studentsshow that, according to them there is no significant differencein Slovenia between exploitation in traffic and other sectors.Thus, general models of exploitation could be used to explainthe behaviour in the traffic sector. Empirical research amongSlovene students showed that according to their statements inthe 90s the managerial and capitalistic types of exploitation prevailedin Slovenia over non-exploitative types of economic behaviour.It also showed that statements of students do not differmuch from those of the general public regarding this question,nor from the statements of irregular students with extensivework experience. It was also found that there were no substantialdifferences between the statements of Italian and Slovenestudents regarding the type of exploitation operative in theircountries. Students of traffic are basically of the same opinionregarding this topic as students in general, though slightly morecritical, especially towards business managers and politicians.

  1. Research Paradigms in Psychosomatic Medicine with Special Emphasis on Whiplash - Cervical Hyperextension Flexion Injury (CHFI

    Directory of Open Access Journals (Sweden)

    Harold Merskey

    2003-01-01

    Full Text Available There have been a number of attempts, particularly in the last five decades to understand the origins of pain in terms of psychological or psychosomatic patterns. These include psychoanalytic explanations relying on hysterical mechanisms, and psychophysiological proposals. The occurrence of pain in the course of psychiatric illness and its remission after the illness, has long been known and is not a controversial issue. However, the reported explanations of pain without overt and obvious prior psychiatric illness have largely failed to convince a significant portion of the professional establishment. These explanations have very often coincided with the interests of insurance companies, whether those insurance companies were providing medical benefits, disability insurance or workers' or accident compensation. Critical examination of the evidence generated by insurance company related research indicates profound weaknesses in it.

  2. Research paradigms in psychosomatic medicine with special emphasis on whiplash - cervical hyperextension flexion injury (CHFI).

    Science.gov (United States)

    Merskey, Harold

    2003-01-01

    There have been a number of attempts, particularly in the last five decades to understand the origins of pain in terms of psychological or psychosomatic patterns. These include psychoanalytic explanations relying on hysterical mechanisms, and psychophysiological proposals. The occurrence of pain in the course of psychiatric illness and its remission after the illness, has long been known and is not a controversial issue. However, the reported explanations of pain without overt and obvious prior psychiatric illness have largely failed to convince a significant portion of the professional establishment. These explanations have very often coincided with the interests of insurance companies, whether those insurance companies were providing medical benefits, disability insurance or workers' or accident compensation. Critical examination of the evidence generated by insurance company related research indicates profound weaknesses in it.

  3. Nuclear microscopy in biomedical analysis with special emphasis on clinical metal biology

    Science.gov (United States)

    Lindh, Ulf; Frisk, Peter; Nyström, Joakim; Danersund, Antero; Hudecek, Romuald; Lindvall, Anders; Thunell, Stig

    1997-07-01

    Nuclear microscopy based upon developments in high energy ion beam techniques is by now an accepted technique in many fields of research. The advancements into the biomedical field have, however, been slower than expected. A major factor explaining this tendency is the availability of nuclear microscopy. This paper reviews briefly the biomedical work using nuclear microscopy that has been carried out since the 4 th International Conference on Nuclear Microprobe Technology and Applications held in Shanghai. Nuclear microscopy of isolated individual blood cells from patients adversely affected by metal exposure from dental amalgam has been performed both before and after removal of the metallic fillings. The elemental profile of blood cells was more or less normalised after treatment. Some of these results will be presented to illustrate a medical application. Results from bulk analysis by ICP-MS of erythrocytes and plasma before and after treatment will also be presented to illustrate the difference in information content between these two approaches as well as the need for complementary information in solving biomedical problems. As part of a larger study of acute porphyria, nuclear microscopy of blood cells was included among the 78 laboratory tests. The approach in this study was unbiased in the sense that no hypothesis was formulated as to which laboratory parameters would be the most explanatory for health or disease. Multivariate discriminant analysis was applied to the large amounts of data acquired. This approach led to the hypothesis that oxidative stress increased the synthesis of manganese-dependent superoxide dismutase in the mitochondria of polymorphonuclear leukocytes, explaining the increase of manganese in these cells. Antioxidant therapy was therefore applied to a couple of patients with porphyria, however, without clinical success.

  4. Gastric lymphomas in Turkey. Analysis of prognostic factors with special emphasis on flow cytometric DNA content.

    Science.gov (United States)

    Aydin, Z D; Barista, I; Canpinar, H; Sungur, A; Tekuzman, G

    2000-07-01

    In contrast to DNA ploidy, to the authors' knowledge the prognostic significance of S-phase fraction (SPF) in gastric lymphomas has not been determined. In the current study, the prognostic significance of various parameters including SPF and DNA aneuploidy were analyzed and some distinct epidemiologic and biologic features of gastric lymphomas in Turkey were found. A series of 78 gastric lymphoma patients followed at Hacettepe University is reported. DNA flow cytometry was performed for 34 patients. The influence of various parameters on survival was investigated with the log rank test. The Cox proportional hazards model was fitted to identify independent prognostic factors. The median age of the patients was 50 years. There was no correlation between patient age and tumor grade. DNA content analysis revealed 4 of the 34 cases to be aneuploid with DNA index values < 1.0. The mean SPF was 33.5%. In the univariate analysis, surgical resection of the tumor, modified Ann Arbor stage, performance status, response to first-line chemotherapy, lactate dehydrogenase (LDH) level, and SPF were important prognostic factors for disease free survival (DFS). The same parameters, excluding LDH level, were important for determining overall survival (OS). In the multivariate analysis, surgical resection of the tumor, disease stage, performance status, and age were found to be important prognostic factors for OS. To the authors' knowledge the current study is the first to demonstrate the prognostic significance of SPF in gastric lymphomas. The distinguishing features of Turkish gastric lymphoma patients are 1) DNA indices of aneuploid cases that all are < 1.0, which is a unique feature; 2) a lower percentage of aneuploid cases; 3) a higher SPF; 4) a younger age distribution; and 5) lack of an age-grade correlation. The authors conclude that gastric lymphomas in Turkey have distinct biologic and epidemiologic characteristics. Copyright 2000 American Cancer Society.

  5. A clinical study on oral lichen planus with special emphasis on hyperpigmentation

    Science.gov (United States)

    Chitturi, Ravi Teja; Sindhuja, Pandian; Parameswar, R. Arjun; Nirmal, Ramdas Madhavan; Reddy, B. Venkat Ramana; Dineshshankar, Janardhanam; Yoithapprabhunath, Thukanayakanpalayam Ragunathan

    2015-01-01

    Background: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population. Materials and Methods: A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software. Results: We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation. Conclusion: Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected. PMID:26538905

  6. Cold Shock Proteins: a Minireview with Special Emphasis on Csp-family of Enteropathogenic Yersinia

    Directory of Open Access Journals (Sweden)

    Riikka Keto-Timonen

    2016-07-01

    Full Text Available Bacteria have evolved a number of mechanisms for coping with stress and adapting to changing environmental conditions. Many bacteria produce small cold shock proteins (Csp as a response to rapid temperature downshift (cold shock. During cold shock, the cell membrane fluidity and enzyme activity decrease, and the efficiency of transcription and translation is reduced due to stabilization of nucleic acid secondary structures. Moreover, protein folding is inefficient and ribosome function is hampered. Csps are thought to counteract these harmful effects by serving as nucleic acid chaperons that may prevent the formation of secondary structures in mRNA at low temperature and thus facilitate the initiation of translation. However, some Csps are non-cold inducible and they are reported to be involved in various cellular processes to promote normal growth and stress adaptation responses. Csps have been shown to contribute to osmotic, oxidative, starvation, pH and ethanol stress tolerance as well as to host cell invasion. Therefore, Csps seem to have a wider role in stress tolerance of bacteria than previously assumed. Yersinia enterocolitica and Yersinia pseudotuberculosis are enteropathogens that can spread through foodstuffs and cause an enteric infection called yersiniosis. Enteropathogenic Yersinia are psychrotrophs that are able to grow at temperatures close to 0ºC and thus they set great challenges for the modern food industry. To be able to efficiently control psychrotrophic Yersinia during food production and storage, it is essential to understand the functions and roles of Csps in stress response of enteropathogenic Yersinia.

  7. Histology, Immunohistochemistry and Ultrastructure of the Bovine Palatine Tonsil with Special Emphasis on Reticular Epithelium

    Science.gov (United States)

    The paired palatine tonsils are located at the junction of the nasopharynx and oropharynx; ideally positioned to sample antigens entering through either the nasal cavity or oral cavity. Entering antigens will first contact tonsilar epithelium. To better understand the cellular and functional composi...

  8. Verifying Elimination Programs with a Special Emphasis on Cysticercosis Endpoints and Postelimination Surveillance

    Directory of Open Access Journals (Sweden)

    Sukwan Handali

    2012-01-01

    Full Text Available Methods are needed for determining program endpoints or postprogram surveillance for any elimination program. Cysticercosis has the necessary effective strategies and diagnostic tools for establishing an elimination program; however, tools to verify program endpoints have not been determined. Using a statistical approach, the present study proposed that taeniasis and porcine cysticercosis antibody assays could be used to determine with a high statistical confidence whether an area is free of disease. Confidence would be improved by using secondary tests such as the taeniasis coproantigen assay and necropsy of the sentinel pigs.

  9. Caroline Furness and the Evolution of Visual Variable Star Observing

    Science.gov (United States)

    Larsen, Kristine

    2017-01-01

    An Introduction to the Study of Variable Stars by Dr. Caroline Ellen Furness (1869-1936), Director of the Vassar College Observatory, was published in October 2015. Issued in honor of the fiftieth anniversary of the founding of Vassar College, the work was meant to fill a void in the literature, namely as both an introduction to the topic of variable stars as well as a manual explaining how they should be observed and the resulting data analyzed. It was judged to be one of the hundred best books written by an American woman in the last hundred years at the 1933 World’s Fair in Chicago. The book covers the relevant history of and background on types of variable stars, star charts, catalogs, and the magnitude scale, then describes observing techniques, including visual, photographic, and photoelectric photometry. The work finishes with a discussion of light curves and patterns of variability, with a special emphasis on eclipsing binaries and long period variables. Furness’s work is therefore a valuable snapshot of the state of astronomical knowledge, technology, and observing techniques from a century ago. Furness’s book and its reception in the scientific community are analyzed, and parallels with (and departures from) the current advice given by the AAVSO to beginning variable star observers today are highlighted.

  10. Multivariate analysis of seasonal variation in the composition and thermal properties of butterfat with an emphasis on authenticity assessment; Análisis multifactorial de la variable estacional sobre la composición y las propiedades térmicas de la grasa de mantequilla, con énfasis en la evaluación de la autenticidad.

    Energy Technology Data Exchange (ETDEWEB)

    Tomaszewska-Gras, J.

    2016-07-01

    The aim of this study was to analyze the seasonal variation in the composition and thermal properties of butterfat (BF) in order to evaluate the applicability of differential scanning calorimetry (DSC) for the authenticity assessment of butter. The composition of fatty acids (FA) and triacylglycerols (TAG) and the thermal properties of genuine BF purchased in the summer and in the winter from six producers were determined. Principal component analysis (PCA) was used to recognize variation and as a result, all BF samples were classified into two groups: one composed of mixed samples from the summer and winter and the other comprising only summer BF samples. DSC and GC analysis revealed that the group of only summer BF samples was characterized by lower melting temperatures and peak heights of low- and medium melting fractions and the highest proportions of unsaturated FAs (ΣC18:1, ΣC18:2, ΣC18:3). The results indicated that most of the variation in the composition and thermal properties was affected by summer BF samples, which may result from the alternative animal feeding systems employed in the summer season, i.e., pasture vs. indoor. Therefore, seasonal variation should be taken into consideration during the elaboration of the analytical method of authenticity assessment. [Spanish] El objetivo de este estudio fue analizar la variable estacional sobre la composición y las propiedades térmicas de grasa de mantequilla (GM) con el fin de evaluar la aplicabilidad de la calorimetría diferencial de barrido (CDB) en la evaluación de la autenticidad de la mantequilla. Se determinó la composición de ácidos grasos (AG) y triglicéridos (TG) y las propiedades térmicas de GM genuina de seis productores en verano e invierno. Se utilizó el análisis de componentes (ACP) principales para reconocer la variación y, como resultado, todas las muestras de GM se clasificaron en dos grupos: uno compuesto de muestras mixtas de verano e invierno y los otro que comprende

  11. International Specialization

    DEFF Research Database (Denmark)

    Kleindienst, Ingo; Geisler Asmussen, Christian; Hutzschenreuter, Thomas

    2012-01-01

    Whether and how international diversification and cross-border arbitrage affects firm performance remains one of the major unresolved research questions in the strategy and international business literatures. We propose that knowing how much a firm has internationally diversified tells us very...... little about performance implications, if we do not know, and do not ask, how the firm has diversified. Therefore, building on the two broad arguments of operating flexibility and location-specific commitment, we develop a theoretical framework that focuses on the extent to which a firm's international...... arbitrage strategy is characterized by specialization versus replication and argue that these different strategies may have differential impact on profitability and risk reduction. Developing a sophisticated measure of international specialization and using a unique panel data set of 92 German MNEs to test...

  12. Special offer

    CERN Multimedia

    Staff Association

    2010-01-01

    Special offer for members of the Staff Association and their families 10% reduction on all products in the SEPHORA shop (sells perfume, beauty products etc.) in Val Thoiry ALL YEAR ROUND. Plus 20% reduction during their “vente privée”* three or four times a year. Simply present your Staff Association membership card when you make your purchase. * next “vente privée” from 24th to 29th May 2010  

  13. Special lecture

    International Nuclear Information System (INIS)

    Yoshikawa, H.

    1998-01-01

    In his special lecture, given at the Artsimovich-Kadomtsev Memorial Session of the 17th IAEA Fusion Energy Conference in Yokohama, October 1998, Prof. H. Yoshikawa stated that the fusion program had come to a crossroads. He was wondering whether the future would lead to cooperation between nations, striving to overcome the difficulties the world is confronted with, or if it would lead to despair

  14. Special offer

    CERN Multimedia

    Staff Association

    2011-01-01

    SPECIAL OFFER FOR OUR MEMBERS Tarif unique Adulte/Enfant Entrée Zone terrestre 19 euros instead of 23 euros Entrée “Zone terrestre + aquatique” 24 euros instead of 31 euros Free for children under 3, with limited access to the attractions. Walibi Rhône-Alpes is open daily from 22 June to 31 August, and every week end from 3 September until 31 October. Closing of the “zone aquatique” 11 September.

  15. Special effects.

    Science.gov (United States)

    Davis, Carol

    The nursing team on the day case ward at Alder Hey Hospital has introduced changes to the environment to help children with special needs, who often attend the ward repeatedly. Small changes, such as keeping colours on the ward neutral, can help children relax. Nurses contact parents a week before admission to find out about their child's likes and dislikes. Parents are encouraged to bring a child's favourite items with them. Operating sessions are scheduled to meet these children's needs.

  16. Policy Challenges and Opportunities for Rural Special Education

    Science.gov (United States)

    Rude, Harvey; Miller, Kevin J.

    2018-01-01

    This article reviews current developments in state and national policies that affect rural special education. A brief overview of the federal role in rural education is provided, with emphasis on the implications for the provision of special education services in rural communities. A variety of challenges are identified, including (a) the variable…

  17. Special Education in Canada: Past, Present and Future.

    Science.gov (United States)

    Hodder, Clive

    The paper reviews the history and present status of special education in Canada (with particular emphasis on the province of Ontario) and identifies recommended future directions. The legislative authority for special education and current policies are summarized in sections on the following provinces: British Columbia, Alberta, Saskatchewan,…

  18. Spinal diffusion tensor imaging: a comprehensive review with emphasis on spinal cord anatomy and clinical applications.

    Science.gov (United States)

    Hendrix, Philipp; Griessenauer, Christoph J; Cohen-Adad, Julien; Rajasekaran, Shanmuganathan; Cauley, Keith A; Shoja, Mohammadali M; Pezeshk, Parham; Tubbs, R Shane

    2015-01-01

    Magnetic resonance imaging technology allows for in vivo visualization of fiber tracts of the central nervous system using diffusion-weighted imaging sequences and data processing referred to as "diffusion tensor imaging" and "diffusion tensor tractography." While protocols for high-fidelity diffusion tensor imaging of the brain are well established, the spinal cord has proven a more difficult target for diffusion tensor methods. Here, we review the current literature on spinal diffusion tensor imaging and tractography with special emphasis on neuroanatomical correlations and clinical applications. © 2014 Wiley Periodicals, Inc.

  19. Special energies and special frequencies

    International Nuclear Information System (INIS)

    Endrullis, M.; Englisch, H.

    1987-01-01

    ''Special frequencies'' have been asserted to be zeros of the density of frequencies corresponding to a random chain of coupled oscillators. Our investigation includes both this model and the random one-dimensional Schroedinger operator describing an alloy or its discrete analogue. Using the phase method we exactly determine a bilateral Lifsic asymptotic of the integrated density of states k(E) at special energies G s , which is not only of the classical type exp(-c/vertical strokeE-E s vertical stroke 1/2 ) but also exp(-c'/vertical strokeE-E s vertical stroke) is a typical behaviour. In addition, other asymptotics occur, e.g. vertical strokeE-E c vertical stroke c '', which show that k(E) need not be C ∞ . (orig.)

  20. Special offers

    CERN Multimedia

    Staff Association

    2011-01-01

    Are you a member of the Staff Association? Did you know that as a member you can benefit from the following special offers: BCGE (Banque Cantonale de Genève): personalized banking solutions with preferential conditions. TPG: reduced rates on annual transport passes for active and retired staff. Aquaparc: reduced ticket prices for children and adults at this Swiss waterpark in Le Bouveret. FNAC: 5% reduction on FNAC vouchers. For more information about all these offers, please consult our web site: http://association.web.cern.ch/association/en/OtherActivities/Offers.html

  1. Special Offers

    CERN Multimedia

    Association du personnel

    2011-01-01

    Are you a member of the Staff Association? Did you know that as a member you can benefit from the following special offers: BCGE (Banque Cantonale de Genève): personalized banking solutions with preferential conditions. TPG: reduced rates on annual transport passes for active and retired staff. Aquaparc: reduced ticket prices for children and adults at this Swiss waterpark in Le Bouveret. Walibi: reduced prices for children and adults at this French attraction park in Les Avenières. FNAC: 5% reduction on FNAC vouchers. For more information about all these offers, please consult our web site: http://association.web.cern.ch/association/en/OtherActivities/Offers.html

  2. Special offer

    CERN Multimedia

    Staff Association

    2011-01-01

    OFFRE SPECIALE POUR NOS MEMBRES Les vendredis 29 juillet, 5 et 12 août, Aquaparc fermera ses portes exceptionnellement à 22h00. Pour ces évènements, des tarifs défiant toute concurrence vous sont proposés. Au programme : Clown spécialiste de la sculpture de ballons de 16h00 à 21h00 Ambiance Salsa avec danseurs professionnel : Démonstration et Cours de Salsa. Les tarifs : Pour une entrée à partir de 15h00 : Enfant : CHF 22.- Adulte : CHF 26.-  

  3. Special graphites

    International Nuclear Information System (INIS)

    Leveque, P.

    1964-01-01

    A large fraction of the work undertaken jointly by the Commissariat a l'Energie Atomique (CEA) and the Pechiney Company has been the improvement of the properties of nuclear pile graphite and the opening up of new fields of graphite application. New processes for the manufacture of carbons and special graphites have been developed: forged graphite, pyro-carbons, high density graphite agglomeration of graphite powders by cracking of natural gas, impervious graphites. The physical properties of these products and their reaction with various oxidising gases are described. The first irradiation results are also given. (authors) [fr

  4. Knowledge on Sclerocarya birrea subsp. caffra with emphasis on its ...

    African Journals Online (AJOL)

    Knowledge on Sclerocarya birrea subsp. caffra with emphasis on its importance as a non-timber forest product in South and southern Africa: a summary: Part 1: Taxonomy, ecology and role in rural livelihoods: review paper.

  5. Pulsating red variables

    International Nuclear Information System (INIS)

    Whitelock, P.A.

    1990-01-01

    The observational characteristics of pulsating red variables are reviewed with particular emphasis on the Miras. These variables represent the last stage in the evolution of stars on the Asymptotic Giant Branch (AGB). A large fraction of the IRAS sources in the Bulge are Mira variables and a subset of these are also OH/IR sources. Their periods range up to 720 days, though most are between 360 and 560 days. At a given period those stars with the highest pulsation amplitudes have the highest mass-loss rates; this is interpreted as evidence for a causal connection between mass-loss and pulsation. It is suggested that once an AGB star has become a Mira it will evolve with increasing pulsation amplitude and mass-loss, but with very little change of luminosity or logarithmic period. 26 refs

  6. Special Offers

    CERN Multimedia

    Association du personnel

    2011-01-01

    Are you a member of the Staff Association? Did you know that as a member you can benefit from the following special offers: BCGE (Banque Cantonale de Genève): personalized banking solutions with preferential conditions.     TPG: reduced rates on annual transport passes for active and retired staff.     Aquaparc: reduced ticket prices for children and adults at this Swiss waterpark in Le Bouveret.     Walibi: reduced prices for children and adults at this French attraction park in Les Avenières.       FNAC: 5% reduction on FNAC vouchers.       For more information about all these offers, please consult our web site: http://association.web.cern.ch/association/en/OtherActivities/Offers.html

  7. Special Offers

    CERN Multimedia

    Staff Association

    2011-01-01

    Are you a member of the Staff Association? Did you know that as a member you can benefit from the following special offers: BCGE (Banque Cantonale de Genève): personalized banking solutions with preferential conditions.     TPG: reduced rates on annual transport passes for all active and retired staff.     Aquaparc: reduced ticket prices for children and adults at this Swiss waterpark in Le Bouveret.     Walibi: reduced prices for children and adults at this French attraction park in Les Avenières.       FNAC: 5% reduction on FNAC vouchers.       For more information about all these offers, please consult our web site: http://association.web.cern.ch/association/en/OtherActivities/Offers.html

  8. Special relativity

    CERN Document Server

    Faraoni, Valerio

    2013-01-01

    This book offers an essential bridge between college-level introductions and advanced graduate-level books on special relativity. It begins at an elementary level, presenting and discussing the basic concepts normally covered in college-level works, including the Lorentz transformation. Subsequent chapters introduce the four-dimensional worldview implied by the Lorentz transformations, mixing time and space coordinates, before continuing on to the formalism of tensors, a topic usually avoided in lower-level courses. The book’s second half addresses a number of essential points, including the concept of causality; the equivalence between mass and energy, including applications; relativistic optics; and measurements and matter in Minkowski spacetime. The closing chapters focus on the energy-momentum tensor of a continuous distribution of mass-energy and its covariant conservation; angular momentum; a discussion of the scalar field of perfect fluids and the Maxwell field; and general coordinates. Every chapter...

  9. Special relativity

    International Nuclear Information System (INIS)

    French, A.P.

    1982-01-01

    This book is an introduction to special relativity theory. After a discussion of the limits of Newton's mechanics and the pecularities in the propagation of light the Lorentz transformation is introduced. Then the measurement of space and time intervals in the framework of relativity theory is considered. Thereafter the addition of velocities and acceleration are considered in this framework. Then relativistic kinematics of particle interactions are described. Then the four-dimensional calculus in space-time coordinates is introduced. Finally an introduction is given to the treatment of the electromagnetic field in the framework of relativity theory. Every chapter contains exercise problems with solutions. This book is suited for all students who want to get some fundamental knowledge about relativity theory. (HSI) [de

  10. Longitudinal Research with Latent Variables

    CERN Document Server

    van Montfort, Kees; Satorra, Albert

    2010-01-01

    This book combines longitudinal research and latent variable research, i.e. it explains how longitudinal studies with objectives formulated in terms of latent variables should be carried out, with an emphasis on detailing how the methods are applied. Because longitudinal research with latent variables currently utilizes different approaches with different histories, different types of research questions, and different computer programs to perform the analysis, the book is divided into nine chapters. Starting from some background information about the specific approach, short history and the ma

  11. Special offers

    CERN Multimedia

    Association du personnel

    2012-01-01

    Special discount to the members of the Staff Association Aquaparc Discounted prices on admission of whole day. Children from 5 to 15 years: 26.– CHF instead of 35.– CHF; Adults from 16 years: 32.– CHF instead of 43.– CHF.Tickets on sale to the Staff Association Secretariat. BCGE Account management on salary account and annual subscription to credit cards free of charge. Other benefits on mortgage loan and financial planning. Comédie de Genève 20% off on full price tickets (also available for partner): from 24 to 32 CHF a ticket instead of 30 to 40 CHF depending on the shows. Ezee Suisse 15% off on the range of electric bikes upon presentation of your Staff Association membership card before payment. FNAC 5% discount on gifts card available in four Swiss shops without any restriction. Gifts card on sale to the Staff Association Secretariat. FutureKids 15% off for the Staff Association members who enrol their children of 5 to 16 years old in ...

  12. Variability Bugs:

    DEFF Research Database (Denmark)

    Melo, Jean

    . Although many researchers suggest that preprocessor-based variability amplifies maintenance problems, there is little to no hard evidence on how actually variability affects programs and programmers. Specifically, how does variability affect programmers during maintenance tasks (bug finding in particular......)? How much harder is it to debug a program as variability increases? How do developers debug programs with variability? In what ways does variability affect bugs? In this Ph.D. thesis, I set off to address such issues through different perspectives using empirical research (based on controlled...... experiments) in order to understand quantitatively and qualitatively the impact of variability on programmers at bug finding and on buggy programs. From the program (and bug) perspective, the results show that variability is ubiquitous. There appears to be no specific nature of variability bugs that could...

  13. Emphasis: Five Ways to Cure Boring Student Writing.

    Science.gov (United States)

    Foster, Mary Ellen

    A careful use of emphasis by students in their writing can be promoted by some exercises assigned by composition teachers. A drawing exercise can help students learn that changing the length of sentences makes paragraphs more interesting. Using Elizabeth Kubler-Ross's five categories of grief to consider times of depression in students' lives…

  14. Livelihood Strategies of Rural Women with Emphasis on Income ...

    African Journals Online (AJOL)

    This article explores some of the livelihood strategies of rural women with emphasis ... per annum, which leads to limited access to the scarce land and other resources. ... livelihood tragedy, about 27% of the rural women respondents began to limit the ... used to move away from home to look for employment opportunities.

  15. Trustworthiness in Evaluation Practice: An Emphasis on the Relational

    Science.gov (United States)

    Rallis, Sharon F.; Rossman, Gretchen B.; Gajda, Rebecca

    2007-01-01

    As canons for trustworthiness developed explicitly in the discourse of qualitative inquiry, the emphasis was on procedural matters rather than fundamentally relational ones. A nod was made to the relational in such strategies as "member checks" but the issues of how the evaluator actually relates to participants and to the larger communities of…

  16. Knowledge on Sclerocarya birrea subsp. caffra with emphasis on its ...

    African Journals Online (AJOL)

    Knowledge on Sclerocarya birrea subsp. caffra with emphasis on its importance as a non-timber forest product in South and southern Africa: a summary: part 2: commercial use, tenure and policy, domestication, intellectual property rights and benefit-sharing: review paper.

  17. A Shift in Emphasis: Comments on CAE's New Mission Statement

    Science.gov (United States)

    Anderson-Levitt, Kathryn M.

    2007-01-01

    In a presidential address prepared for the 2006 Council on Anthropology and Education (CAE) meeting, I argue that the new mission statement for CAE represents not a new direction for the organization, but simply a shift in emphasis, albeit an important and timely shift.

  18. Malignant tumors of the nasal cavity and paranasal sinuses: long-term outcome and morbidity with emphasis on hypothalamic-pituitary deficiency

    NARCIS (Netherlands)

    Snyers, An; Janssens, Geert O. R. J.; Twickler, Marcel B.; Hermus, Ad R.; Takes, Robert P.; Kappelle, Arnoud C.; Merkx, Matthias A. W.; Dirix, Piet; Kaanders, Johannes H. A. M.

    2009-01-01

    PURPOSE: To evaluate the long-term outcome after surgery and radiotherapy for patients with sinonasal cancer and assess late toxicity, with special emphasis on hypothalamic-pituitary dysfunction. METHODS AND MATERIALS: A retrospective analysis of 168 patients treated for sinonasal cancer in a single

  19. On the propagation of linear longitudinal acoustic waves in isotropic media with shear and volume viscosity and a tensorial internal variable. II. Some cases of special interest (Poynting-Thomson, Jeffreys, Maxwell, Kelvin-Voigt, Hooke and Newton media)

    NARCIS (Netherlands)

    Ciancio, V.; Turrisi, E.; Kluitenberg, G.A.

    1986-01-01

    In a previous paper the propagation of linear longitudinal acoustic waves in isotropic media with shear and volume viscosity and a tensorial internal variable was considered and the expressions for the velocity and attenuation of the waves were obtained. In the present paper we investigate the

  20. Window in Iran Islamic Architecture with Emphasis on Role of Light

    Directory of Open Access Journals (Sweden)

    Fatemeh Kateb

    2018-03-01

    Full Text Available Presence of light during history and in various architectural oeuvres, in addition to functional aspect, as factor for illumination and life conferring to daily activities, it has been abundantly addressed from spiritual aspect and in doctrinal discussions of religions. During Islamic epoch, light was manifestation of god existence and for this reason, it is respected and deemed as sacred. Islamic architecture particularly in Iran has a special emphasis on the light. This study is carried out by descriptive analytical method. Results showed that window as the inlet of light preserves light presence hierarchy, also in symbolic and mystical concepts like excellence, upward tendency and establishing a spiritual space in architecture, each one has been manifested in some way or another.

  1. Nuclear air cleaning: the need for a change in emphasis

    International Nuclear Information System (INIS)

    Carbaugh, E.H.

    1982-11-01

    The nuclear industry now has over 35 years of experience in nuclear air cleaning. This experience covers technology development, system design, operations, and maintenance. Much of the past experience has been directed towards technology development with particular emphasis on high efficiency particulate air (HEPA) filters. Implementation of this technology has lagged its development by a number of years. A recent study examines the cause and frequencies of HEPA filter changeouts and failures. These data lead to a conclusion that a shift in emphasis from technology development to the training of personnel and the designing and maintaining of such systems is needed. Some highlights of the data and a discussion of topics which should be addressed in training will be presented

  2. Nuclear air cleaning: the need for a change in emphasis

    International Nuclear Information System (INIS)

    Carbaugh, E.H.

    1983-01-01

    The nuclear industry now has over 35 years of experience in nuclear air cleaning. This experience covers technology development, system design, operations, and maintenance. Much of the past experience has been directed towards technology development with particular emphasis on high efficiency particulate air (HEPA) filters. Implementation of this technology has lagged its development by a number of years. A recent study examines the causes and frequencies of HEPA filter changeouts and failures. These data lead to a conclusion that a shift in emphasis from technology development to the training of personnel and the designing and maintaining of such systems is needed. Some highlights of the data and a discussion of topics which should be addressed in training will be presented. 7 references, 5 tables

  3. Laryngeal schwannoma: a case report with emphasis on sonographic findings

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Luis Ronan Marquez Ferreira de, E-mail: luisronan@gmail.com [Universidade Federal do Triangulo Mineiro (UFTM), Uberaba, MG (Brazil); De Nicola, Harley; Yamasaki, Rosiane; Pedroso, Jose Eduardo; Brasil, Osiris de Oliveira Campones do; Yamashita, Helio [Universidade Federal de Sao Paulo (EPM/UNIFESP), Sao Paulo, SP (Brazil). Escola Paulista de Medicina

    2014-05-15

    Schwannomas are benign nerve sheath tumors composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral, cranial and autonomic nerves. Twenty-five to forty-five percent of all schwannomas occur in the head and neck region, but location of such tumors in the larynx is rarely observed. The present report is aimed at describing a clinical case of laryngeal schwannoma, with emphasis on sonographic findings. (author)

  4. Pulsating variables

    International Nuclear Information System (INIS)

    1989-01-01

    The study of stellar pulsations is a major route to the understanding of stellar structure and evolution. At the South African Astronomical Observatory (SAAO) the following stellar pulsation studies were undertaken: rapidly oscillating Ap stars; solar-like oscillations in stars; 8-Scuti type variability in a classical Am star; Beta Cephei variables; a pulsating white dwarf and its companion; RR Lyrae variables and galactic Cepheids. 4 figs

  5. Algorithmically specialized parallel computers

    CERN Document Server

    Snyder, Lawrence; Gannon, Dennis B

    1985-01-01

    Algorithmically Specialized Parallel Computers focuses on the concept and characteristics of an algorithmically specialized computer.This book discusses the algorithmically specialized computers, algorithmic specialization using VLSI, and innovative architectures. The architectures and algorithms for digital signal, speech, and image processing and specialized architectures for numerical computations are also elaborated. Other topics include the model for analyzing generalized inter-processor, pipelined architecture for search tree maintenance, and specialized computer organization for raster

  6. Variable-cycle engines for supersonic cruise aircraft

    Science.gov (United States)

    Willis, E.

    1976-01-01

    Progress and the current status of the Variable Cycle Engine (VCE) study are reviewed with emphasis placed on the impact of technology advancements and design specifications. A large variety of VCE concepts are also examined.

  7. Computer model for refinery operations with emphasis on jet fuel production. Volume 3: Detailed systems and programming documentation

    Science.gov (United States)

    Dunbar, D. N.; Tunnah, B. G.

    1978-01-01

    The FORTRAN computing program predicts flow streams and material, energy, and economic balances of a typical petroleum refinery, with particular emphasis on production of aviation turbine fuels of varying end point and hydrogen content specifications. The program has a provision for shale oil and coal oil in addition to petroleum crudes. A case study feature permits dependent cases to be run for parametric or optimization studies by input of only the variables which are changed from the base case.

  8. Revisiting Caroline Furness's An Introduction to the Study of Variable Stars on its Centenary (Poster abstract)

    Science.gov (United States)

    Larsen, K.

    2016-06-01

    (Abstract only) A century and one month ago (October 1915) Dr. Caroline Ellen Furness (1869-1936), Director of the Vassar College Observatory, published An Introduction to the Study of Variable Stars. Issued in honor of the fiftieth anniversary of the founding of Vassar College, the work was meant to fill a void in the literature, namely as both an introduction to the topic of variable stars and as a manual explaining how they should be observed and the resulting data analyzed. It was judged to be one of the hundred best books written by an American woman in the last hundred years at the 1933 World's Fair in Chicago. The book covers the relevant history of and background on types of variable stars, star charts, catalogs, and the magnitude scale, then describes observing techniques, including visual, photographic, and photoelectric photometry. The work finishes with a discussion of light curves and patterns of variability, with a special emphasis on eclipsing binaries and long period variables. Furness's work is a valuable snapshot of the state of astronomical knowledge, technology, and observing techniques from a century ago. This presentation will analyze both Furness's book and its reception in the scientific community, and draw parallels to current advice given to beginning variable star observers.

  9. Cognitive Variability

    Science.gov (United States)

    Siegler, Robert S.

    2007-01-01

    Children's thinking is highly variable at every level of analysis, from neural and associative levels to the level of strategies, theories, and other aspects of high-level cognition. This variability exists within people as well as between them; individual children often rely on different strategies or representations on closely related problems…

  10. Antimicrobial activity of lysozyme with special relevance to milk ...

    African Journals Online (AJOL)

    This review discusses the antimicrobial activity of lysozyme with special emphasis on milk's lysozyme, and attempts to shed some light on the recent advances elucidating the mechanism of its antimicrobial activity against sensitive microorganisms as well as the means used by some bacteria to resist such an activity.

  11. Opinion on Recent Developments and the Future of Special Education

    Science.gov (United States)

    Kauffman, James M.

    2015-01-01

    Three encouraging trends in special education are greater focus on instruction, emphasis on positive approaches to problem behavior, and greater reliance on scientific evidence. Next steps involving instruction should include research on modifications of instruction needed to accommodate learners with disabilities and on the place in which these…

  12. Attitudes of Korean Dental Students Toward Individuals with Special Health Care Needs.

    Science.gov (United States)

    Lee, Hyo-Seol; Jung, Hoi In; Kim, Seon-Mi; Kim, Jiyoen; Doh, Re Mee; Lee, Jae-Ho

    2015-09-01

    The purposes of this study were to ascertain the attitudes of dental students toward individuals with special health care needs (SHCNs) in Korea and to elucidate the characteristics associated with these attitudes. The authors recruited students from four of the 11 dental schools in Korea to participate in a survey; these schools were selected for regional balance. The Scale of Attitudes toward Disabled Persons (SADP) was used as the primary survey instrument, and ten independent variables were included. Of the 1,100 possible participants, 1,057 responded to the survey, for a response rate of 96.1%. The results showed that although the students' attitudes did not differ significantly by gender, their attitudes did show statistically significant differences on nine other variables: age, year, religion, self-esteem, friends with a disability, volunteering, admission course, concern for individuals with SHCNs, and intention to treat individuals with SHCNs (all p<0.05). The attitudes of these Korean dental students toward individuals with SHCNs were relatively unfavorable, showing lower SADP scores than reported in Western countries and likely reflecting Eastern cultural values in general. Future efforts should place greater emphasis on special care dentistry education and encourage the development of more favorable attitudes regarding the treatment of individuals with SHCNs.

  13. Non-diffractive optically variable security devices

    NARCIS (Netherlands)

    Renesse, R.L. van

    1991-01-01

    At the past optical security conferences attention was focused on diffractive structures, e.g. holograms, embossed gratings and thin—film devices, as security elements on valuable documents. The main reasons for this emphasis are, that the iridescent effect of such diffractive optically variable

  14. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2017-10-17

    Oct 17, 2017 ... incipal emphasis is on radiative transitions between electronic states, both ... also allows the prediction of intensity and transition probability .... For the steady state condition, the rate of high level triplet state is equal to zero.

  15. The Affordances and Constraints of Special Education Initial Teacher Licensure Policy for Teacher Preparation

    Science.gov (United States)

    Blanton, Linda P.; Boveda, Mildred; Munoz, Lorena R.; Pugach, Marleen C.

    2017-01-01

    Initial licensure polices in special education were examined to determine how these policies support or hinder reform efforts to develop teacher education programs that prepare graduates for the increasingly complex needs of diverse students. Initial special education licensure policies are described with an emphasis on the differences across…

  16. Melhoramento florestal: ênfase na aplicação da biotecnologia Forestry improvement: emphasis on biotechnology application

    Directory of Open Access Journals (Sweden)

    Diego Pascoal Golle

    2009-08-01

    Full Text Available As espécies florestais possuem grande importância econômica, pois oferecem diversos produtos fundamentais para a sociedade. Técnicas de melhoramento podem aumentar a produtividade das florestas plantadas, oferecer características desejadas à indústria e reduzir impactos ambientais. No entanto, a baixa variabilidade existente em espécies florestais de crescimento rápido, o longo período para os ciclos reprodutivos e as dificuldades encontradas para a realização de cruzamentos controlados podem inviabilizar tais procedimentos. O objetivo deste trabalho foi realizar uma revisão sobre a contribuição do Melhoramento Genético em espécies perenes, relatando técnicas convencionais e dando especial ênfase à biotecnologia. A cultura de tecidos, a utilização de marcadores moleculares e a transformação genética oferecem soluções únicas para o melhoramento florestal. As principais características que vêm sendo melhoradas estão ligadas à produção de biomassa, alteração na composição de lignina, resistência a pragas, tolerância a herbicidas, macho-esterilidade e fitorremediação. Contribuições significativas para a indústria e o ambiente têm sido alcançadas por meio dessas técnicas.Forest species have great economic importance due to the wide range of important products offered to society. Techniques improvement can increase the productivity of planted forests, providing the desired characteristics to industry, as well as, reducing environmental impacts. However, the low variability existing in fast-growing species, the long reproductive cycles period and the difficulties encountered when conducting controlled crossings may prevent such procedures. The aim of this research was to carry out a review on the contribution of genetic improvement in perennial species. Conventional techniques with special emphasis on biotechnology were reported. The tissue culture, the use of molecular markers and genetic transformation

  17. Consumer attitudes to food quality products : emphasis on Southern Europe

    NARCIS (Netherlands)

    Klopcic, M.; Kuipers, A.; Hocquette, J.F.

    2012-01-01

    Quality foods, such as traditional, EU certified, organic and health claimed are part of a growing trend towards added value in the agri-food sector. In these foods, elements of production, processing, marketing, agro-tourism and speciality stores are combined. Paramount above all is the link to the

  18. Complex variables

    CERN Document Server

    Fisher, Stephen D

    1999-01-01

    The most important topics in the theory and application of complex variables receive a thorough, coherent treatment in this introductory text. Intended for undergraduates or graduate students in science, mathematics, and engineering, this volume features hundreds of solved examples, exercises, and applications designed to foster a complete understanding of complex variables as well as an appreciation of their mathematical beauty and elegance. Prerequisites are minimal; a three-semester course in calculus will suffice to prepare students for discussions of these topics: the complex plane, basic

  19. Euratom research and training in generation IV systems with emphasis on V/HTR

    International Nuclear Information System (INIS)

    Goethem, G. van; Manolatos, P.; Fuetterer, M.

    2006-01-01

    In this overview paper, the following questions are addressed: (1) What are the challenges facing the European Union nuclear fission research community in the short (today), medium (2010) and long term (2040)? (2) What kind of research and technological development (RTD) does Euratom offer to respond to these challenges, in particular in the area of reactor systems and fuel cycles? In the general debate about energy supply technologies there are challenges of both a scientific and technological (S/T) as well as an economic and political (E/P) nature. Though the Community research programme acts mainly on the former, there is nevertheless important links with Community policy. These not only exist in the specific area of nuclear policy. It is shown in the particular area of nuclear fission, to what extent Euratom research, education and innovation ('Knowledge Triangle: Education, Research, and Innovation') respond to the S/T challenges: (1) sustainability, (2) economics, (3) safety, and (4) proliferation resistance. At the European Commission (EC), the research related to nuclear reactor systems and fuel cycles is principally under the responsibility of the 2 Directorates Generals (DG) DG Research (RTD, located in Brussels), which implements and manages the programme of 'indirect actions', and the DG Joint Research Centre (JRC, headquarters in Brussels and 7 scientific institutes in 5 Member States) which carries out 'direct actions' in their own laboratories. In this HTR-2006 introductory paper, the emphasis is on the indirect and direct actions of the 6 th Euratom research framework programme 2003-2006, FP-6, with special emphasis on V/HTR Generation IV research. (orig.)

  20. Legislation regarding social protection of children and youth in Sweden with particular emphasis on protection from abuse and neglect

    Directory of Open Access Journals (Sweden)

    Savić Slobodan 2

    2003-01-01

    Full Text Available Protection of children from abuse and neglect is a current problem in the world. The consequences of violence against children are very important because they can leave behind permanent bodily injuries up to severe invalidity, as well as psychological consequences which very often lead to transmission of violence into next generations. In most extreme cases death occurs as a consequence of abuse and neglect. In this paper authors present legislation which regulate social protection of children and youth in Sweden, with special emphasis on protection from abuse and neglect. Sweden is a country in which social care of most vulnerable groups including children, was always at the top of priorities. Authors made comparative analysis of Swedish and domestic (Serbian laws regarding protection of children from violence, with particular emphasis on mandatory report of these cases from professionals who are in regular professional contact with children. Authors will also put emphasis on duties of medical doctors in the system of protection of children and youth from abuse and neglect.

  1. Breeding of speciality maize for industrial purposes

    OpenAIRE

    Pajić Zorica; Radosavljević Milica; Filipović Milomir; Todorović Goran; Srdić Jelena; Pavlov Milovan

    2010-01-01

    The breeding programme on speciality maize with specific traits was established at the Maize Research Institute, Zemun Polje, several decades ago. The initial material was collected, new methods applying to breeding of speciality maize, i.e. popping maize, sweet maize and white-seeded maize, were introduced. The aim was to enhance and improve variability of the initial material for breeding these three types of maize. Then, inbred lines of good combining abilities were developed and used as c...

  2. External evaluation policies: emphasis in the cognitive and socioemotional competences

    Directory of Open Access Journals (Sweden)

    Elma Júlia Gonçalves de Carvalho

    2016-09-01

    Full Text Available This article presents reflections on the Brazilian policies for external evaluation with the aim to question the relevance of the emphasis that has been given to the different skills. Thereunto, we analyze the goals, the basis and the references of Brazilian main basic education test (Prova Brasil and the SENNA Project, relating them to the new capital requirements and directions of international organizations from the 1990s. According to the analysis, initially, external evaluations focused on the amount of knowledge obtained, and later began to be guided by the model of different types of skills, influencing the way teachers assess and handle knowledge, that is their pedagogical conceptions. The results show that the logic of competences corresponds to a trend in political and pedagogical directions of denial of scientific and cultural knowledge, and of the school role as responsible for the distribution, as equally as possible, of systematized knowledge.

  3. Imaging of pancreatic adenocarcinoma with emphasis on multidetector CT

    International Nuclear Information System (INIS)

    Smith, S.L.; Rajan, P.S.

    2004-01-01

    Pancreatic adenocarcinoma is the fourth most frequent cause of cancer-related death. The incidence is increasing and the overall survival has altered little in recent years. Moreover, patients usually present late with inoperable disease and curative resection by standard pancreatico-duodenectomy (Whipple's procedure) is associated with significant morbidity. It should only be attempted in that small group of patients lacking radiological evidence of advanced disease. Despite the recent advances in body magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS), computed tomography (CT) is the mainstay of staging in most centres and the recent development of multidetector CT machines (MDCT) has raised hope of an improvement in preoperative staging. This review focuses on the CT of pancreatic adenocarcinoma with particular emphasis on examination technique and on those criteria that determine resectability

  4. Imaging of pancreatic adenocarcinoma with emphasis on multidetector CT

    Energy Technology Data Exchange (ETDEWEB)

    Smith, S.L. E-mail: simon.smith@ipsh-tr.anglox.nhs.uk; Rajan, P.S

    2004-01-01

    Pancreatic adenocarcinoma is the fourth most frequent cause of cancer-related death. The incidence is increasing and the overall survival has altered little in recent years. Moreover, patients usually present late with inoperable disease and curative resection by standard pancreatico-duodenectomy (Whipple's procedure) is associated with significant morbidity. It should only be attempted in that small group of patients lacking radiological evidence of advanced disease. Despite the recent advances in body magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS), computed tomography (CT) is the mainstay of staging in most centres and the recent development of multidetector CT machines (MDCT) has raised hope of an improvement in preoperative staging. This review focuses on the CT of pancreatic adenocarcinoma with particular emphasis on examination technique and on those criteria that determine resectability.

  5. Lifelong Teacher Education in the Czechoslovakian Socialist Republic with Especial Reference to the Training of Teachers in Special Education.

    Science.gov (United States)

    Cerna, Marie

    1987-01-01

    The structure of the Czechoslovak system of preservice and inservice teacher education introduced by Education Act No. 29 of 1984 is described. The preparation of special education teachers is given particular emphasis. (Author/MT)

  6. Special Education in Nigeria.

    Science.gov (United States)

    Abang, Theresa B.

    1992-01-01

    This article discusses the special education system in Nigeria, focusing on integration; training of special educators; medical, health, and welfare services for children with disabilities; recreational facilities; employment opportunities; national planning; and problems and successes. (JDD)

  7. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2018-03-07

    Mar 7, 2018 ... characterized by historically developed specialization, a special geographical location ... We are listed under Research Associations category. ... product, service or technology providing economic and/or public benefit, additional in ...... the region's competitiveness // International Business Management.

  8. Variable stars

    International Nuclear Information System (INIS)

    Feast, M.W.; Wenzel, W.; Fernie, J.D.; Percy, J.R.; Smak, J.; Gascoigne, S.C.B.; Grindley, J.E.; Lovell, B.; Sawyer Hogg, H.B.; Baker, N.; Fitch, W.S.; Rosino, L.; Gursky, H.

    1976-01-01

    A critical review of variable stars is presented. A fairly complete summary of major developments and discoveries during the period 1973-1975 is given. The broad developments and new trends are outlined. Essential problems for future research are identified. (B.R.H. )

  9. Influência de variáveis do treinamento contra-resistência sobre a força muscular de idosos: uma revisão sistemática com ênfase nas relações dose-resposta Influencia de las variables de entrenamiento contra-resistencia sobre la fuerza muscular de ancianos: una revisión sistemática con énfasis en las relaciones dosis-respuesta Influence of counter-resistance training variables on elderly muscular strength: a systematic review with emphasis on dose/response relationships

    Directory of Open Access Journals (Sweden)

    Nádia Lima da Silva

    2007-02-01

    tiene aún muy claro cuál es la mejor combinación de esas variables para una óptima relación dosis-respuesta en personas ancianas. El objetivo de este estudio ha sido analizar las investigaciones sobre entrenamiento de fuerza para ancianos, mediante una revisión sistemática, con el propósito de identificar tendencias comunes en términos de efectos del entrenamiento provocados por la manipulación de estas variables. Una vez definidos los criterios de inclusión, fueron seleccionados 22 estudios, agrupados por semejanza de tratamiento (nº de series, frecuencia semanal, intensidad, intervalos y orden de los ejercicios. Técnicas de estadística descriptiva auxiliaron en la determinación de posibles tendencias en las relaciones dosis-respuesta. Al identificarse, esas tendencias fueron analizadas cualitativamente. De todas las variables revisadas, solamente para la intensidad de sobrecarga fueron encontradas evidencias, lo que permite afirmar que cargas mayores serían más eficaces para inducir un aumento de fuerza a esa edad. En relación a las demás variables, los resultados disponibles en la literatura no dan respaldo para realizar inferencias seguras respecto al mejor delineamiento de programas de entrenamiento que alíen, al mismo tiempo, efectividad y seguridad. Por tanto, se recomienda que estudios posteriores sean realizados para comparar experimentalmente los efectos de la manipulación de esas variables sobre la fuerza muscular de ancianos.Muscular force is considered an important component of physical exercise programs. The results of this type of training depend on the combination of the number of repetitions, series, overload, sequence and intervals between series and exercises. However, it is still not very clear yet what the best combination of these variables for a good stimulus/response relationship in elderly people is. The objective of this study was to analyze the research on power-training for elderly people by means of systematic revision

  10. Nuclear safety considerations with emphasis on instrumentation and control systems

    International Nuclear Information System (INIS)

    Beare, J.W.

    1978-01-01

    The conceptual model of a nuclear power plant in Canada is that it consists basically of two kinds of systems. The first kind is the process systems, that is, those structures and components associated with the production of nuclear energy and its conversion to other forms of energy. The second kind is the special safety systems, whose purpose it is to protect the public in the event of a serious failure in the process systems which might otherwise lead to unacceptable radiological consequences. Quantitative limits are set on the unavailability of the special safety systems. These limits are low enough to be consistent with low overall risk and yet can be demonstrated by test during operation of the plant. Low unavailability is an important but not the only condition required for low unrealiability for the special safety systems. The special safety systems minimize the chance of a cross-linked failure particularly under the conditions experienced as a result of the more severe types of postulated serious process failures. Nuclear power plants must also withstand, without a major hazard to the public, certain rare events associated with natural phenomena or man-made activities off-site and also certain in-plant events such as fire or break-up of a turbine-generator which might have a cross-linking effect on process and safety systems. In the latest designs, Canadian nuclear power plants have emergency systems to deal with such events. The emergency systems have an enhanced degree of physical and functional separation from other plant systems. (author)

  11. Dinoflagellate community structure from the stratified environment of the Bay of Bengal, with special emphasis on harmful algal bloom species

    Digital Repository Service at National Institute of Oceanography (India)

    Naik, R.K.; Hegde, S.; Anil, A.C.

    the total marine phytoplankton species, approximately 7% are capable of forming algal blooms (red tides) (Sournia 1995); dinoflagellates are the most important group producing toxic and harmful algal blooms (Steidinger 1983, 1993; Anderson 1989... Taxonomic identification revealed 134 species of dinoflagellates in surface waters of the BOB during the observation period (Table 2). Further grouping of these identified species based on their nutritional mode, revealed 40 autotrophic, 50 mixotrophic...

  12. Preclinical tools in PET-tracer development : automatisation and biopharmaceutical evaluation with special emphasis on the adenosine A3 receptor

    International Nuclear Information System (INIS)

    Haeusler, D. I. B.

    2010-01-01

    Positron Emission Tomography (PET) is the first choice technology for the visualization and quantification of receptors and transporters, enabling examination of e.g. neurological, psychiatric and oncological diseases on a molecular level. Therefore, new and innovative PET-radiopharmaceuticals need to be developed to get further insights into the biochemical mechanisms involved in pathological changes. PET-tracer development starts with the idea or modelling of the chemical structure of a (new) molecule with (hopefully) good binding characteristics to the desired target site. As next steps, the compound needs to be synthesized and radiolabelled with a suitable PET-nuclide. Then it has to be evaluated regarding its parameters in various preclinical experimental settings. Hence, two major tools are crucial in the development-process of new PET-tracers: 1) a fast and reliable production method, most desirable and optimal in an automated set-up, and 2) proof of tracer suitability (high affinity, high selectivity and specificity, beside low unspecific binding) through preclinical evaluation in an animal model, prior to human application. Both aspects, the radiochemical preparation and automatisation, as well as the biopharmaceutical evaluation are presented in the thesis in 5 different manuscripts. In detail, the development and preclinical evaluation of 4 different PET-tracers ([11C]DASB, [18F]FE SUPPY, [18F]FE SUPPY:2, and [18F]FE CIT) for 3 targets, the serotonin transporter (SERT), the adenosine A3 receptor (A3R) and the dopamine transporter (DAT), respectively, are covered in the present thesis. The first manuscript presents a method for a fast, reliable and fully-automated radiosynthesis of [11C]DASB (a tracer for the imaging of the SERT in human brain in e.g. depression patients) will facilitate further clinical investigations (e.g. for the department of psychiatry and psychotherapy of the medical university of Vienna) with this tracer. [18F]FE SUPPY was introduced as the first A3R PET-tracer recently. The adenosine A3 receptor is expressed in high levels in tumor cells, but not in the majority of normal cells. Potential application of a tracer for the A3R will be inflammation processes, oncological diseases as solid tumors; breast-, colon-, lung-, pancreas-, prostate-, melanoma- and brain metastases, as well as ischemia (brain and heart) and neurological pathologies as glaucoma and epilepsy. [18F]FE SUPPY:2, a completely new potential 18F-fluoroethylated radiotracer for the A3R, is presented in the thesis. The thesis covers the radiochemical preparation of [18F]FE SUPPY:2 and the automation of the radiosyntheses of both radiotracers in manuscript 2 and 3. Moreover, preclinical evaluations (affinity, selectivity, unspecific binding, biodistribution, logP, autoradiography and in-vitro and ex-vivo metabolic stability) of the two tracers were conducted, and also a comparison of these parameters are given in manuscripts 3 and 4. [18F]FE CIT, a potential new tracer for imaging of the DAT for e.g. Parkinson patients, was successfully further evaluated in terms of metabolic stability against CES and autoradiographic distribution on rat brain slices. The high selectivity of [18F]FE CIT over SERT and NET was confirmed in this study, and furthermore, it was even significantly higher than the selectivity of the well known tracers [123I]ß-CIT and [123I]FP-CIT. Based on these results, we aim for the future diagnostic application of [18F]FE CIT in humans with neurological and psychiatric diseases caused by changes in the dopaminergic system (e.g. Parkinson s disease, depression, drug abuse). (author) [de

  13. Consequences of EU enlargement for supply and demand in the electricity market with special emphasis on nuclear power

    International Nuclear Information System (INIS)

    Jaeger, G.

    2004-01-01

    After the enlargement of the European Union, Europe has acquired a new dimension which is reflected also on the electricity market. The aggregate European electricity requirement of 3 000 TWh in Europe constitutes approximately one quarter of the world electricity generation. Nuclear power contributes a major share of 966 TWh. In electricity generation from nuclear power, EU-25 is No. 1 in the world. The rising demand for electricity cannot be met by the existing power plant park in the next few decades. Insufficient possibilities of exchange among countries and, especially, the enormous requirement to replace more than 200,000 MW of electricity generating capacity in Europe by 2020, plus another 100,000 MW arising from growing demand, make a comprehensive renewal of the European power plant park indispensable. After the EU enlargement, the standards of the ''old'' European Union are the yardstick for the entire ''new'' Union. This gives rise to enormous efforts, especially in the accession countries, to curb emissions and increase safety. The need for modern power plant technology is becoming particularly apparent in these cases. The example of the ten new member countries clearly shows the options realistically available for electricity generation in the future and indispensable for a favorable infrastructure. The conventional energy resources, i. e. coal, gas, and nuclear power, will be the main sources of electricity generation in Europe over the next few decades. This finding does not meet the expectations of many members of the public who feel that renewables would make the largest contribution to power supply in twenty years' time. This makes it imperative to regain popular acceptance in order to ensure electricity generation at favorable conditions and at a high level of environmental protection in the whole of Europe, with enough leeway to further advance the expansion of renewables and support a positive economic development of Europe. (orig.)

  14. Hydrogeomorphic and hydraulic habitats of the Niobrara River, Nebraska-with special emphasis on the Niobrara National Scenic River

    Science.gov (United States)

    Alexander, Jason S.; Zelt, Ronald B.; Schaepe, Nathan J.

    2010-01-01

    The Niobrara River is an ecologically and economically important resource in Nebraska. The Nebraska Department of Natural Resources' recent designation of the hydraulically connected surface- and groundwater resources of the Niobrara River Basin as ?fully appropriated? has emphasized the importance of understanding linkages between the physical and ecological dynamics of the Niobrara River so it can be sustainably managed. In cooperation with the Nebraska Game and Parks Commission, the U.S. Geological Survey investigated the hydrogeomorphic and hydraulic attributes of the Niobrara River in northern Nebraska. This report presents the results of an analysis of hydrogeomorphic segments and hydraulic microhabitats of the Niobrara River and its valley for the approximately 330-mile reach from Dunlap Diversion Dam to its confluence with the Missouri River. Two spatial scales were used to examine and quantify the hydrogeomorphic segments and hydraulic microhabitats of the Niobrara River: a basin scale and a reach scale. At the basin scale, digital spatial data and hydrologic data were analyzed to (1) test for differences between 36 previously determined longitudinal hydrogeomorphic segments; (2) quantitatively describe the hydrogeomorphic characteristics of the river and its valley; and (3) evaluate differences in hydraulic microhabitat over a range of flow regimes among three fluvial geomorphic provinces. The statistical analysis of hydrogeomorphic segments resulted in reclassification rates of 3 to 28 percent of the segments for the four descriptive geomorphic elements. The reassignment of classes by discriminant analysis resulted in a reduction from 36 to 25 total hydrogeomorphic segments because several adjoining segments shared the same ultimate class assignments. Virtually all of the segment mergers were in the Canyons and Restricted Bottoms (CRB) fluvial geomorphic province. The most frequent classes among hydrogeomorphic segments, and the dominant classes per unit length of river, are: a width-restricted valley confinement condition, sinuous-planview pattern, irregular channel width, and an alternate bar configuration. The Niobrara River in the study area flows through a diversity of fluvial geomorphic settings in its traverse across northern Nebraska. In the Meandering Bottoms (MB) fluvial geomorphic province, river discharge magnitudes are low, and the valley exerts little control on the channel-planview pattern. Within the CRB province, the river flows over a diversity of geologic formations, and the valley and river narrow and expand in approximate synchronicity. In the Braided Bottoms (BB) fluvial geomorphic province, the river primarily flows over Cretaceous Pierre Shale, the valley and channel are persistently wide, and the channel slope is generally uniform. The existence of vegetated islands and consequent multithread channel environments, indicated by a higher braided index, mostly coincided with reaches having gentler slopes and less unit stream power. Longitudinal hydrology curves indicate that the flow of the Niobrara River likely is dominated by groundwater as far downstream as Norden. Unit stream power values in the study area vary between 0 and almost 2 pounds per foot per second. Within the MB province, unit stream power steadily increases as the Niobrara gains discharge from groundwater inflow, and the channel slope steepens. The combination of steep slopes, a constrained channel width, and persistent flow within the CRB province results in unit stream power values that are between three and five times greater than those in less confined segments with comparable or greater discharges. With the exception of hydrogeomorphic segment 3, which is affected by Spencer Dam, unit stream power values in the BB province are generally uniform. Channel sinuosity values in the study area varied generally between 1 and 2.5, but with locally higher values measured in the MB province and at the entrenched bedrock me

  15. Terra nullius, Inuit Habitation and Norse Occupation – With Special Emphasis on the 1933 East Greenland Case

    Directory of Open Access Journals (Sweden)

    Peter Thomas Ørebech

    2016-05-01

    Full Text Available Sovereignty acquired by occupation entails “recognize[d] title based on discovery,” “a reasonable period [of] … effective occupation of the region claimed to be discovered” and “the continuous and peaceful display of State authority.” Only terra nullius is subject to occupation. A territory inhabited by indigenous groups that sustain social and political organization may impede an occupying power because the terra nullius requirement fails. While sovereignty over thinly populated areas are often lax, case law requires less public involvement in these sparsely inhabited areas. This study reveals that the Dano-Norwegian Kings regarded the Inuit as “our subjects.” The Kings’ pretention of absolutum dominium and jurisdiction involved both the Norse and Inuit ethnic groups and “bygð ok ubygð” (settled and unsettled land. The exodus of the Norse peoples in 1450 AD for 200 years did not undermine the acquired sovereignty of the Dano-Norwegian Crown, which as a result, spoiled the 1931 Norwegian pretentions to legally occupy East-Greenland. Denmark's triumph in the 1933-East Greenland case resulted from a “zero-sum principle.” More than a 100 years earlier, the Danish Kingdom lost a succession of countries and dependencies. The 1814 Kiel Treaty transferred mainland Norway to Sweden, but explicitly states that none of the ancient Norwegian dependencies, Greenland, Iceland and Faroe Islands would follow suit. Thus, these territories remained part of the Kingdom of Denmark.

  16. Simulation and analysis of collapsing vapor-bubble clusters with special emphasis on potentially erosive impact loads at walls

    Science.gov (United States)

    Ogloblina, Daria; Schmidt, Steffen J.; Adams, Nikolaus A.

    2018-06-01

    Cavitation is a process where a liquid evaporates due to a pressure drop and re-condenses violently. Noise, material erosion and altered system dynamics characterize for such a process for which shock waves, rarefaction waves and vapor generation are typical phenomena. The current paper presents novel results for collapsing vapour-bubble clusters in a liquid environment close to a wall obtained by computational fluid mechanics (CFD) simulations. The driving pressure initially is 10 MPa in the liquid. Computations are carried out by using a fully compressible single-fluid flow model in combination with a conservative finite volume method (FVM). The investigated bubble clusters (referred to as "clouds") differ by their initial vapor volume fractions, initial stand-off distances to the wall and by initial bubble radii. The effects of collapse focusing due to bubble-bubble interaction are analysed by investigating the intensities and positions of individual bubble collapses, as well as by the resulting shock-induced pressure field at the wall. Stronger interaction of the bubbles leads to an intensification of the collapse strength for individual bubbles, collapse focusing towards the center of the cloud and enhanced re-evaporation. The obtained results reveal collapse features which are common for all cases, as well as case-specific differences during collapse-rebound cycles. Simultaneous measurements of maximum pressures at the wall and within the flow field and of the vapor volume evolution show that not only the primary collapse but also subsequent collapses are potentially relevant for erosion.

  17. Functional Genomic Approaches for the Study of Fetal/Placental Development in Swine with Special Emphasis on Imprinted Genes

    Science.gov (United States)

    The overall focus of this chapter will be the application of functional genomic approaches for the study of the imprinted gene family in swine. While there are varied definitions of “functional genomics” in general they focus on the application of genomic approaches such as DNA microarrays, single n...

  18. A Conceptual Schema of the Programming Process in the Complex Adult Education Organization with Special Emphasis on Its Sociological Aspects.

    Science.gov (United States)

    Boone, Edgar J.; And Others

    Objectives of this paper were to define the concept of programing, to discuss programing in a complex adult education organization, and to point out aspects of programing of a sociological nature. Programing is a decision-making process. In a complex adult education organization, the process can be divided into eight phases: formulating the…

  19. Treatment of Fibromyalgia Syndrome: Recommendations of Recent Evidence-Based Interdisciplinary Guidelines with Special Emphasis on Complementary and Alternative Therapies

    Directory of Open Access Journals (Sweden)

    Jacob Ablin

    2013-01-01

    Full Text Available Objective. Current evidence indicates that there is no single ideal treatment for fibromyalgia syndrome (FMS. First choice treatment options remain debatable, especially concerning the importance of complementary and alternative medicine (CAM treatments. Methods. Three evidence-based interdisciplinary guidelines on FMS in Canada, Germany, and Israel were compared for their first choice and CAM-recommendations. Results. All three guidelines emphasized a patient-tailored approach according to the key symptoms. Aerobic exercise, cognitive behavioral therapy, and multicomponent therapy were first choice treatments. The guidelines differed in the grade of recommendation for drug treatment. Anticonvulsants (gabapentin, pregabalin and serotonin noradrenaline reuptake inhibitors (duloxetine, milnacipran were strongly recommended by the Canadian and the Israeli guidelines. These drugs received only a weak recommendation by the German guideline. In consideration of CAM-treatments, acupuncture, hypnosis/guided imagery, and Tai Chi were recommended by the German and Israeli guidelines. The Canadian guidelines did not recommend any CAM therapy. Discussion. Recent evidence-based interdisciplinary guidelines concur on the importance of treatment tailored to the individual patient and further emphasize the need of self-management strategies (exercise, and psychological techniques.

  20. Anti-Müllerian Hormone and Its Clinical Use in Pediatrics with Special Emphasis on Disorders of Sex Development

    DEFF Research Database (Denmark)

    Lindhardt Johansen, Marie; Hagen, Casper P; Johannsen, Trine Holm

    2013-01-01

    Using measurements of circulating anti-Müllerian hormone (AMH) in diagnosing and managing reproductive disorders in pediatric patients requires thorough knowledge on normative values according to age and gender. We provide age- and sex-specific reference ranges for the Immunotech assay and conver......Using measurements of circulating anti-Müllerian hormone (AMH) in diagnosing and managing reproductive disorders in pediatric patients requires thorough knowledge on normative values according to age and gender. We provide age- and sex-specific reference ranges for the Immunotech assay...

  1. Satellite Power Systems (SPS) concept definition study. Volume 5: Special emphasis studies. [rectenna and solar power satellite design studies

    Science.gov (United States)

    Hanley, G. M.

    1980-01-01

    Satellite configurations based on the Satellite Power System baseline requirements were analyzed and a preferred concept selected. A satellite construction base was defined, precursor operations incident to establishment of orbital support facilities identified, and the satellite construction sequence and procedures developed. Rectenna construction requirement were also addressed. Mass flow to orbit requirements were revised and traffic models established based on construction of 60 instead of 120 satellites. Analyses were conducted to determine satellite control, resources, manufacturing, and propellant requirements. The impact of the laser beam used for space-to-Earth power transmission upon the intervening atmosphere was examined as well as the inverse effect. The significant space environments and their effects on spacecraft components were investigated to define the design and operational limits imposed by the environments on an orbit transfer vehicle. The results show that LEO altitude 300 nmi and transfer orbit duration 6 months are preferrable.

  2. Philippine Sea Plate inception, evolution, and consumption with special emphasis on the early stages of Izu-Bonin-Mariana subduction

    Science.gov (United States)

    Lallemand, Serge

    2016-12-01

    We compiled the most relevant data acquired throughout the Philippine Sea Plate (PSP) from the early expeditions to the most recent. We also analyzed the various explanatory models in light of this updated dataset. The following main conclusions are discussed in this study. (1) The Izanagi slab detachment beneath the East Asia margin around 60-55 Ma likely triggered the Oki-Daito plume occurrence, Mesozoic proto-PSP splitting, shortening and then failure across the paleo-transform boundary between the proto-PSP and the Pacific Plate, Izu-Bonin-Mariana subduction initiation and ultimately PSP inception. (2) The initial splitting phase of the composite proto-PSP under the plume influence at ˜54-48 Ma led to the formation of the long-lived West Philippine Basin and short-lived oceanic basins, part of whose crust has been ambiguously called "fore-arc basalts" (FABs). (3) Shortening across the paleo-transform boundary evolved into thrusting within the Pacific Plate at ˜52-50 Ma, allowing it to subduct beneath the newly formed PSP, which was composed of an alternance of thick Mesozoic terranes and thin oceanic lithosphere. (4) The first magmas rising from the shallow mantle corner, after being hydrated by the subducting Pacific crust beneath the young oceanic crust near the upper plate spreading centers at ˜49-48 Ma were boninites. Both the so-called FABs and the boninites formed at a significant distance from the incipient trench, not in a fore-arc position as previously claimed. The magmas erupted for 15 m.y. in some places, probably near the intersections between back-arc spreading centers and the arc. (5) As the Pacific crust reached greater depths and the oceanic basins cooled and thickened at ˜44-45 Ma, the composition of the lavas evolved into high-Mg andesites and then arc tholeiites and calc-alkaline andesites. (6) Tectonic erosion processes removed about 150-200 km of frontal margin during the Neogene, consuming most or all of the Pacific ophiolite initially accreted to the PSP. The result was exposure of the FABs, boninites, and early volcanics that are near the trench today. (7) Serpentinite mud volcanoes observed in the Mariana fore-arc may have formed above the remnants of the paleo-transform boundary between the proto-PSP and the Pacific Plate.

  3. Impact of urban waste water treatment on sludge utilization and disposal with special emphasis on thermal treatment

    International Nuclear Information System (INIS)

    Gammeltoft, P.

    1993-01-01

    The acceptance of the European Communities Directive 9/271/CEE concerning urban waste water treatment by all the EC Member States will result in a sewage sludge production increase of 2 to 3 times the actual amounts (for the year 2000 the forecast is about 30 million tonnes per year). All the traditional sewage sludge treatment methods (agricultural, disposal, compost, thermal treatment) entail costs which are always increasing because of the stricter requirements; in addition EC policy is oriented towards the reduction of the quantity of sludge production. In some situations, drying and subseque incineration may thus be the only practicable method of disposal, particularly, in very large urban agglomerations

  4. Survey for bats in the Los Alamos National Environmental Research Park, with special emphasis on the spotted bat, Euderma maculatum

    Energy Technology Data Exchange (ETDEWEB)

    Tyrell, K.; Brack, V. Jr.

    1992-10-29

    To increase knowledge about the presence of endangered species and their habitat at the LANL, 3D/Environmental Services, Inc. conducted a mist net survey for bats on Laboratory lands. In addition to documenting the presence of threatened and endangered species, this survey was conducted to gain more knowledge about the diversity and distribution of the bat fauna existing on the Laboratory. There are 25 species of bats found in New Mexico, about 16 of which are likely to occur in the region of the Laboratory. Of particular interest was documentation of the presence of the spotted bat, Euderma maculatum. The spotted bat is listed as Endangered, Group 2 by the State of New Mexico, and is a Federal Candidate for listing as endangered. As such, conservation of this species and its habitat should be a management priority on the Laboratory. A total of 94 bats were captured in 16 net nights, between 30 June and 05 July 1992. Thirteen species of bats were caught during the study: Antrozous pallidus (pallid bat), 10.6 percent; Eptesicus fuscus (big brown bat), 10.6 percent; Lasionycteris noctivigans (silver-haired bat), 16 percent; Lasiurus cinereus (hoary bat), 11.7 percent; Myotis californicus (California myotis), 4.3 percent; M. evotis (long-eared myotis), 7.4 percent; M. leibii (small-footed myotis), 5.3 percent; M. thysanodes (fringed myotis), 13.8 percent; M. volans (long-legged myotis), 7.4 percent of the catch; M. yumanensis,(Yuma myotis), 5.3 percent; Pipistrellus hesperus (western pipistrelle), 1.1 percent; Plecotus townsendii (Townsend`s big-eared bat), 1.1 percent, and Tadarida brasiliensis (Brazilian free-tailed bat), 5.3 percent.

  5. Survey for bats in the Los Alamos National Environmental Research Park, with special emphasis on the spotted bat, Euderma maculatum

    Energy Technology Data Exchange (ETDEWEB)

    Tyrell, K.; Brack, V. Jr.

    1992-10-29

    To increase knowledge about the presence of endangered species and their habitat at the LANL, 3D/Environmental Services, Inc. conducted a mist net survey for bats on Laboratory lands. In addition to documenting the presence of threatened and endangered species, this survey was conducted to gain more knowledge about the diversity and distribution of the bat fauna existing on the Laboratory. There are 25 species of bats found in New Mexico, about 16 of which are likely to occur in the region of the Laboratory. Of particular interest was documentation of the presence of the spotted bat, Euderma maculatum. The spotted bat is listed as Endangered, Group 2 by the State of New Mexico, and is a Federal Candidate for listing as endangered. As such, conservation of this species and its habitat should be a management priority on the Laboratory. A total of 94 bats were captured in 16 net nights, between 30 June and 05 July 1992. Thirteen species of bats were caught during the study: Antrozous pallidus (pallid bat), 10.6 percent; Eptesicus fuscus (big brown bat), 10.6 percent; Lasionycteris noctivigans (silver-haired bat), 16 percent; Lasiurus cinereus (hoary bat), 11.7 percent; Myotis californicus (California myotis), 4.3 percent; M. evotis (long-eared myotis), 7.4 percent; M. leibii (small-footed myotis), 5.3 percent; M. thysanodes (fringed myotis), 13.8 percent; M. volans (long-legged myotis), 7.4 percent of the catch; M. yumanensis,(Yuma myotis), 5.3 percent; Pipistrellus hesperus (western pipistrelle), 1.1 percent; Plecotus townsendii (Townsend's big-eared bat), 1.1 percent, and Tadarida brasiliensis (Brazilian free-tailed bat), 5.3 percent.

  6. Reform of investment policy in the function of sustainable development with special emphasis on investment in information technologies

    Directory of Open Access Journals (Sweden)

    Dragičević-Radičević Tatjana

    2017-01-01

    Full Text Available Global economy still records a decline in FDI. The main causes are increased economic instability and geopolitical risks. Given the continued negative trend, it is clear that it is necessary to reform the investment policies at the national, regional, bilateral, multilateral and international level, to ensure sustainable economic development. Key elements of the reforms are: to provide instruments to reduce risks, create mechanisms of responsible investment, improve the structural coherence and promote regional investments. Refer to the current dates of the sectors investments (according to the report of UNCTAD from 2015th shows that the services sector recorded double growth compared to the investment in the manufacturing sector in 2012. Also, if we take into consideration the fact that investment in IT sector investment involves three aspects: transactional (minimizing costs, strategic (innovation technologies, achieving competitiveness and information (improving access to information and communications, it may be assumed that the reforms in the investment policies should be directly correlated with investments in information technology.

  7. Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil

    Directory of Open Access Journals (Sweden)

    Vučinić Marijana

    2012-01-01

    Full Text Available The paper reviews the latest studies on possible applications of oregano essential oil in veterinary medicine and animal livestock production. The first part of the paper deals with the definition of essential oils, possibilities for their extraction from plants, possibilities for their application in human and veterinary medicine, the interest of a science in essential oils, and, essential oils classification based on their use in human and veterinary medicine. The second part of the review deals with the properties of oregano essential oil, its main active principles, carvacrol and thymol and its application in veterinary medicine and animal livestock production. Oregano essential oil may be applied in animal feed, in the treatment of coccidiosis of domestic animals and candidiasis. It can be applied as a larvicide, repellent, insecticide and acaricide. It is used in aquaculture to treat fish diseases caused by bacteria and parasites or in the hatchery industry as a disinfectant for eggs or for disinfection of manure. The greatest potential of oregano essential oil is the possibility of its application in organic agriculture and organic animal husbandry. [Projekat Ministarstva nauke Republike Srbije, br. TR 31087

  8. An overview of some historical knowledge organisation systems and classifications with a special emphasy on monastery libraries’ classification

    Directory of Open Access Journals (Sweden)

    Sonja Svoljšak

    2005-01-01

    Full Text Available The article gives an overview of some most prominent historical turning – points in the field of knowledge organization an2d western European sistematization of science, based on Greek and christian philosophy. Some examples of earlier attempts to unify the systems of knowledge organization and science systematization are presented. Some specific systems of the most prominent European christian religious orders’ library contents arrangement and classification are described in this context.

  9. Seasonal variation in physicochemical properties of coastal waters of Kalpakkam, east coast of India with special emphasis on nutrients.

    Science.gov (United States)

    Satpathy, K K; Mohanty, A K; Natesan, U; Prasad, M V R; Sarkar, S K

    2010-05-01

    A study pertaining to the seasonal variation in physicochemical properties of the coastal waters was carried out at Kalpakkam coast for a period of 1 year (February 2006 to January 2007). It revealed that the coastal water was significantly influenced by freshwater input during North East (NE) monsoon and post-monsoon periods. Concentration of all the nutrients and dissolved oxygen (DO) was relatively high during the NE monsoon, whereas, salinity and chlorophyll-a (chl-a) were at their minimum level during this period. Phytoplankton production peak was observed in summer during which a typical marine condition prevailed. The present observed values of nitrate, phosphate, silicate, and turbidity are significantly high (five to ten times) compared to that of the pre-Tsunami period from this coast. Relatively low DO and chl-a concentration was noticed during the post-Tsunami period. A notable feature of this study is that though nutrient concentration in the coastal waters during post-Tsunami period has increased significantly, turbidity, the most single dominating factor, was found to adversely affect the phytoplankton production during post-Tsunami period as reflected by relatively low chl-a concentration. Thus, the post-Tsunami period may result in a change in coastal biodiversity pattern concomitant with change in coastal water quality.

  10. Some reproductive health indicators in Ukraine : A study with special emphasis on factors behind induced aboartion and perinatal mortality

    OpenAIRE

    Mogilevkina, Iryna

    2002-01-01

    Objectives: To study indicators specifically reflecting the reproductive health of Ukrainian women and to analyse factors behind the indicators. Methods: Induced abortion and maternal mortality were studied in some countries/regions of the former Soviet Union, using official statistics. Abortion rates, contraceptive practices and intentions in Ukrainian women were analysed by a large self-completion survey in 1996, and by a classroom questionnaire to first year medical students in 1999 in Do...

  11. Earthquake precursory studies in Kangra valley of North West Himalayas, India, with special emphasis on radon emission

    International Nuclear Information System (INIS)

    Kumar, Arvind; Singh, Surinder; Mahajan, Sandeep; Bajwa, Bikramjit Singh; Kalia, Rajeev; Dhar, Sunil

    2009-01-01

    The continuous soil gas radon monitoring is carried out at Palampur and the daily monitoring of radon concentration in water is carried out at Dharamshala region of Kangra valley of North West Himalayas, India, a seismic zone V, to study the correlation of radon anomalies in relation to seismic activities. In this study, radon monitoring in soil was carried out by using barasol probe manufactured by Algade France, whereas the radon content in water was recorded using RAD 7 radon monitoring system of Durridge Company USA. The effect of meteorological parameters viz. temperature, pressure, wind velocity, rainfall, and humidity on radon emission has been studied. The seasonal average value and standard deviation of radon in soil and water is calculated to find the radon anomaly to minimize the effect of meteorological parameters on radon emission. The radon anomalies observed in the region have been correlated with the seismic events of M≥2 reported by Wadia Institute of Himalayas Geology Dehradoon and Indian Meteorological Department, New Delhi in NW Himalayas within 250 km distance from the monitoring stations.

  12. Occupational hazards and diseases among workers in emergency services: a literature review with special emphasis on Chile

    Directory of Open Access Journals (Sweden)

    Rosa Jiménez Paneque

    2015-08-01

    Full Text Available ANTECEDENTES Los trabajadores de la salud se enfrentan a riesgos de accidentes y enfermedades relacionados con su ocupación. El estrés psíquico, el contacto con enfermedades transmisibles y la violencia son quizás los principales riesgos. Los trabajadores de los servicios de urgencia están sometidos a ellos, con mayor frecuencia que los de otras áreas. La presente revisión tiene por objetivo evaluar el estado del tema en la literatura internacional, y en particular el tratamiento que a este tema se le ha dado en Chile. MÉTODOS Se revisó principalmente la base de datos PubMed de MEDLINE. La estrategia de búsqueda general incluyó las palabras clave: health personnel, emergency medical services y occupational diseases combinadas con otras más específicas. Se revisó también el estado de la prevención de riesgos laborales en los servicios de urgencia. RESULTADOS Se detectaron más de 70 estudios que abordaban el tema de uno u otro riesgo laboral en servicios de urgencia. En Chile se detectan 12 estudios que tocan el tema de riesgos laborales en trabajadores de la salud, al menos dos de ellos abordan los servicios de urgencia. CONCLUSIONES La presente revisión permite valorar el panorama general de los riesgos y enfermedades laborales de los servicios de urgencia, pero no permite la profundidad que amerita cada uno de los riegos mencionados aquí. Se recomienda continuar profundizando en el tema de los riesgos laborales de los trabajadores de los servicios de urgencia, con el fin de contribuir a perfeccionar las medidas de prevención y evaluar sus

  13. The Antithesis of Entropy: Biosemiotic Communication from Genetics to Human Language with Special Emphasis on the Immune Systems

    Directory of Open Access Journals (Sweden)

    John W. Oller

    2010-03-01

    Full Text Available Entropy can be defined as the antithesis of well-formed true reports that agree with each other and with the material facts accessible through the experience of one or more competent observers. The abstract convergence (strictly formal, logical agreement of true narrative representations (TNRs—ordinary valid reports of facts of experience—makes them formally more complete than fictions, errors, lies, and nonsense. A limit of absolute entropy is theoretically reached if all resemblance to a TNR is lost. As argued here, TNRs—formally defined along the lines of Peirce's exact logic—provide the necessary foundation for functional human languages and for biosemiotic systems. The theoretical concepts of pragmatic mapping—the fitting of a TNR to whatever facts it represents—and the constructive cycle of abstraction that enables a child to discover the systems underlying such mappings are introduced and illustrated from child development and then shown to apply to the human neuroarchitecture, genetics, fetal development, and our immune systems. It is also argued that biological disorders and disease conditions logically must involve corrupted (damaged, undeveloped, or otherwise incomplete representations at one or many levels.

  14. Cardiovascular Outcomes of PCSK9 Inhibitors: With Special Emphasis on Its Effect beyond LDL-Cholesterol Lowering

    Directory of Open Access Journals (Sweden)

    Dhrubajyoti Bandyopadhyay

    2018-01-01

    Full Text Available PCSK9 inhibitors, monoclonal antibodies, are novel antihypercholesterolemic drugs. FDA first approved them in July 2015. PCSK9 protein (692-amino acids was discovered in 2003. It plays a major role in LDL receptor degradation and is a prominent modulator in low-density lipoprotein cholesterol (LDL-C metabolism. PCSK9 inhibitors are monoclonal antibodies that target PCSK9 protein in liver and inhibiting this protein leads to drastically lowering harmful LDL-C level in the bloodstream. Despite widespread use of the statin, not all the high-risk patients were able to achieve targeted level of LDL-C. Using PCSK9 inhibitors could lead to a substantial decrement in LDL-C plasma level ranging from 50% to 70%, either as a monotherapy or on top of statins. A large number of trials have shown robust reduction of LDL-C plasma level with the use of PCSK9 inhibitors as a monotherapy or in combination with statins in familial and nonfamilial forms of hypercholesterolemia. Moreover, PCSK9 inhibitors do not appear to increase the risk of hepatic and muscle-related side effects. PCSK9 inhibitors proved to be a highly potent and promising antihypercholesterolemic drug by decreasing LDL-R lysosomal degradation by PCSK9 protein. Statin drugs are known to have some pleiotropic effects. In this article, we are also focusing on the effects of PCSK9 inhibitor beyond LDL-C reduction like endothelial inflammation, atherosclerosis, its safety in patients with diabetes, obesity, and chronic kidney disease, and its influence on neurocognition and stroke.

  15. The human prion diseases. A review with special emphasis on new variant CJD and comments on surveillance.

    LENUS (Irish Health Repository)

    Keohane, C

    2012-02-03

    The transmissible spongiform encephalopathies or prion diseases represent a new group of diseases with unique clinical and neuropathological features, the transmission of which is both genetic and infectious. The responsible agent is unconventional and appears to be largely composed of a glycoprotein, the prion protein PrP. This is normally present on different cells. In prion diseases, it becomes converted to the pathogenic form PrPres which is resistant to proteinase and accumulates within the brain and this process is accompanied by the development of spongiform change, gliosis and neuronal loss. The human prion diseases include Kuru a progressive cerebellar degeneration with late dementia affecting Fore tribes in New-Guinea, now almost extinct, regarded as being related to cannibalism. Creutzfeldt-Jakob disease is the more frequent human prion disease. Its incidence is approximately one case per million per year. Four variants are now recognized: sporadic, familial, iatrogenic and the new variant. The latter represents a distinct clinico-pathological entity. It is now widely accepted that it is due to the same agent responsible for Bovine Spongiform Encephalopathy in cattle. Gerstmann-Straussler-Scheinker disease is a very rare inherited disorder due to a number of different mutations in the PRP gene, characterized by abundant deposits of plaque PrPres in the cerebral grey matter. Fatal familial insomnia is another inherited disorder due to a mutation at codon 178 of the PRP gene associated with methionine on codon 129 of the mutant allele. The main neuropathological change is neuronal loss in the thalamus with little or no spongiosis and usually no PrPres deposition. Following the emergence of new variant CJD in 1996, surveillance of all forms of prion diseases has been now been actively introduced in many European nations in order to determine the true incidence and geographic distribution of these rare disorders in humans.

  16. Treatment of fibromyalgia syndrome: recommendations of recent evidence-based interdisciplinary guidelines with special emphasis on complementary and alternative therapies.

    Science.gov (United States)

    Ablin, Jacob; Fitzcharles, Mary-Ann; Buskila, Dan; Shir, Yoram; Sommer, Claudia; Häuser, Winfried

    2013-01-01

    Objective. Current evidence indicates that there is no single ideal treatment for fibromyalgia syndrome (FMS). First choice treatment options remain debatable, especially concerning the importance of complementary and alternative medicine (CAM) treatments. Methods. Three evidence-based interdisciplinary guidelines on FMS in Canada, Germany, and Israel were compared for their first choice and CAM-recommendations. Results. All three guidelines emphasized a patient-tailored approach according to the key symptoms. Aerobic exercise, cognitive behavioral therapy, and multicomponent therapy were first choice treatments. The guidelines differed in the grade of recommendation for drug treatment. Anticonvulsants (gabapentin, pregabalin) and serotonin noradrenaline reuptake inhibitors (duloxetine, milnacipran) were strongly recommended by the Canadian and the Israeli guidelines. These drugs received only a weak recommendation by the German guideline. In consideration of CAM-treatments, acupuncture, hypnosis/guided imagery, and Tai Chi were recommended by the German and Israeli guidelines. The Canadian guidelines did not recommend any CAM therapy. Discussion. Recent evidence-based interdisciplinary guidelines concur on the importance of treatment tailored to the individual patient and further emphasize the need of self-management strategies (exercise, and psychological techniques).

  17. Imaging analyses of odontogenic infection involving the maxillofacial fascial spaces, with special emphasis on the parapharyngeal space

    Energy Technology Data Exchange (ETDEWEB)

    Ariji, Yoshiko; Gotoh, Masakazu; Izumi, Masahiro; Naitoh, Munetaka; Kurita, Kenichi; Natsume, Nagato; Ariji, Eiichiro [Aichi-Gakuin Univ., Nisshin (Japan). School of Dentistry

    2002-01-01

    The purpose of this study was to investigate odontogenic infection pathways into the maxillofacial fascial spaces, especially into the parapharyngeal space, in relation to causal tooth and clinical symptoms. CT and MR images were retrospectively investigated in 47 patients with spread of odontogenic infection into the maxillofacial spaces. The involvement of spaces was evaluated based on lateral asymmetry of their shapes and density on CT images or intensity on MR images. Involvement on images was observed in 70%, 49%, and 30% of the submandibular, the masticator, and the parapharyngeal spaces, respectively. Patients with submandibular space involvement often had spontaneous pain. Of 14 patients with parapharyngeal space involvement, 8 patients showed dysphagia and/or fever, and 13 patients showed involvement of the mandibular molar as a cause of infection. All of these 14 patients also had submandibular space involvement, while only 7 patients (50%) showed changes in the medial pterygoid muscle. The fat layer between the medial pterygoid muscle and parapharyngeal space was maintained in 11 of 14 (79%) patients with parapharyngeal involvement. CT and MR images clearly demonstrated the spread of odontogenic infection into the maxillofacial spaces. Involvement of the parapharyngeal space was mostly caused by infection originating in the mandibular molar, and was considered to be secondary spread from the submandibular space and/or medial pterygoid muscle. (author)

  18. The Right to Appeal as a Fundamental Right under International Acts and Jurisprudence, with Special Emphasis on Criminal Procedure

    Directory of Open Access Journals (Sweden)

    Vilard BYTYQI

    2017-03-01

    Full Text Available The right to appeal, respectively the right on complaint as per our legal vocabulary, constitutes the basic trunk of the second phase of court decisions in a certain procedure, in particular the criminal proceedings. The aim of this paper is to emphasize the main notions of appeal, but also in other aspects through the comparative description it aims to bring more clarity in differences and similarities that exist in between the appeal which is used in our criminal proceedings and the appeal which is used in the criminal proceedings that take place in the supranational courts. It is known that in courts which consist of international elements, the appeal is positioned in a more advanced level, due to the fact that there are grounds of suspicion used over every element that could be used in any national criminal proceedings. Overall, in any place of the world, the appeal has the goal to remedy court decisions brought by the court of first instance, while, in the procedural aspect it has more or less differences depending on the regulations of criminal procedures of that state. Such difference due to the diversity of the legal systems today are also accepted as the universal legal value, since establishment of international tribunals provides the best practice in this field.

  19. Study of the Knowledge, Attitude and Experience of Medical Tourism Among Target Groups with Special Emphasis on South India

    OpenAIRE

    A, Rajeev; Latif, Sanam

    2009-01-01

    Medical tourism aims at providing cost-effective customized health care in collaboration with the tourism industry in distant locations wherein the hospitality component is handled efficiently so that fixing appointments, making arrangements for accommodation and other logistics become hassle-free for the patient. This allows more concentration on the procedure at hand and the interaction between the medical fraternity and the patient becomes smoother. More and more hospitals in India are gea...

  20. In vitro gastrointestinal digestion study of a novel bio-tofu with special emphasis on the impact of microbial transglutaminase

    Directory of Open Access Journals (Sweden)

    Guangliang Xing

    2016-12-01

    Full Text Available We have developed a novel bio-tofu, made from mixed soy and cow milk (MSCM, using Lactobacillus helveticus MB2-1 and Lactobacillus plantarum B1-6 incorporated with microbial transglutaminase (MTGase as coagulant. MTGase was added to improve the textural properties and suit for cooking. However, the effect of MTGase on the digestion of mixed-protein fermented by lactic acid bacteria was unclear. This study aimed at evaluating the effect of MTGase on protein digestion of bio-tofu under simulated gastrointestinal digestion condition. The results showed that addition of MTGase could affect the particle size distribution, degree of hydrolysis, the content of soluble proteins and free amino acids. Based on the electrophoresis data, MTGase addition enhanced protein polymerization. During gastric and intestinal digestion process, proteins from bio-tofu were degraded into low molecular mass peptides. Our results suggested that incorporation of MTGase could lead to enzymatic modification of proteins of bio-tofu which may help in controlling energy intake and decrease the chance of food allergy.

  1. New advances of TMEM88 in cancer initiation and progression, with special emphasis on Wnt signaling pathway.

    Science.gov (United States)

    Ge, Yun-Xuan; Wang, Chang-Hui; Hu, Fu-Yong; Pan, Lin-Xin; Min, Jie; Niu, Kai-Yuan; Zhang, Lei; Li, Jun; Xu, Tao

    2018-01-01

    Transmembrane protein 88 (TMEM88), a newly discovered protein localized on the cell membrane. Recent studies showed that TMEM88 was involved in the regulation of several types of cancer. TMEM88 was expressed at significantly higher levels in breast cancer (BC) cell line than in normal breast cell line with co-localized with Dishevelled (DVL) in the cytoplasm of BC cell line. TMEM88 silencing in the ovarian cancer cell line CP70 resulted in significant upregulation of Wnt downstream genes (c-Myc, cyclin-D1) and other Wnt target genes including JUN, PTIX2, CTNNB1 (β-catenin), further supporting that TMEM88 inhibits canonical Wnt signaling pathway. Wnt signaling pathway has been known to play important roles in many diseases, especially in cancer. For instance, hepatocellular carcinoma (HCC) has become one of the most common tumors harboring mutations in the Wnt signaling pathway. As the inhibitor of Wnt signaling, TMEM88 has been considered to act as an oncogene or a tumor suppressor. Up-regulated TMEM88 or gene therapy approaches could be an effective therapeutic approach against tumor as TMEM88 inhibits Wnt signaling through direct interaction with DVL. Here, we review the current knowledge on the functional role and potential clinical application of TMEM88 in the control of various cancers. Highlights Wnt signaling displays an important role in several pathogenesis of cancer. Wnt signaling pathway is activated during cancer development. TMEM88 has an impact on cancer by inhibiting canonical Wnt signaling. We discuss the importance and new applications of TMEM88 in cancer therapy. © 2017 Wiley Periodicals, Inc.

  2. Possible impacts of climate change on the water balance with special emphasis on runoff and hydropower potential

    International Nuclear Information System (INIS)

    Frey, S.

    2015-01-01

    Hydropower is the most important source of renewable energy as 20 % of the world’s electricity is provided by hydropower stations. Climate change has impacts on the hydrological cycle and therefore on the hydroelectric power potential. This thesis presents two approaches to study possible impacts of climate change on the hydrological cycle. One focusses on the evolution of climate and its hydrological impact in Austria, the other concentrates on large regions in the Alps. In both studies the regional climate models ALADIN, REMO and RegCM3 were used with the IPCC emission scenario A1B. Mainly due to warming, snowmelt will become more important in winter and early spring while the total amount of snow being stored in the catchment in the cold season will become lower. Consequently, discharge rates in winter in general will be higher. In summer enhanced evapotranspiration combined with less snow and ice melt will lead to lower discharge rates. Annual sums of runoff in most of the basin will be decreasing. Since the modelled catchments cover high mountainous regions snow processes play a key role. The use of a temperature based snowmelt model may lead to unrealistic high accumulations of snow in the peak regions. The presented study deals with that problem in two ways. (i) A simple snow redistribution model has been developed for the use in the raster based hydrological model COSERO. This model has been tested in the catchment of Ötztaler Ache, Austria. This model handles accumulations more realistic but also predicts discharge more precisely leading to a Kling-Gupta-Efficiency of 0.93 instead of 0.9. (ii) Another approach for preventing snow accumulations in high altitudes has been developed for the semi-distributed model used for climate change impact modelling. Similar behaviour regarding snow accumulations and the critical elevation for this to occur has been found in the Salzach River basin, Austria. (author) [de

  3. The radiological impacts of uranium mill tailings - A review with special emphasis on the tailings at Ranstad in Sweden

    International Nuclear Information System (INIS)

    Snihs, J.O.

    1978-01-01

    The environmental impact of uranium mill talings can be expressed in collective dose commitment and corresponding detriment per MWe.y energy produced by the uranium which corresponds to the amount of waste interest, The methods of dose commitment calculations are discussed and it is suggested for the purpose of estimation of the detriment to limit the commitment to 10,000 years. The external radiation from the tailings is easily reduced by covering but in case of a future settlement on the tailings the collective dose commitment will be some hundreds to thousands of manrad/MWe.y depending on the quality of the uranium ore. The dispersion of dust from uncovered tailings is mainly a local problem and the collective dose commitment for critical tissues in the lung will be less than a manrad/MWe.y. In the long run the cover may be lost and the resultant collective dose commitment for the critical tissues in the lung will be a few tens of manrad/MWe.y depending on the quality of the tailings. The effects of global dispersion of the material in the tailings are also discussed

  4. Conjunctival malignant melanoma in Denmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile

    DEFF Research Database (Denmark)

    Larsen, Ann-Cathrine

    2016-01-01

    Conjunctival malignant melanoma is a rare disease associated with considerable mortality. Most published data have been based on case reports or series of referred patients. In addition, very little is known about the genetic and epigenetic profile of conjunctival melanoma and the resemblance to ...... melanoma patients may benefit from therapies that are effective for cutaneous and mucosal melanoma. Additionally, the identification of several up-regulated microRNAs may prove to be useful as prognostic or therapeutic targets in conjunctival melanoma...

  5. Comparison of Organic Matter Composition in Agricultural versus Forest Affected Headwaters with Special Emphasis on Organic Nitrogen

    DEFF Research Database (Denmark)

    Heinz, Marlen; Graeber, Daniel; Zak, Dominik

    2015-01-01

    . By comparing six agriculturally and six forest-impacted headwater streams, we demonstrated that agriculture promotes increased DOC and DON concentrations, entailing an even more pronounced effect on DON. The major part of DOC and DON in agricultural and forest reference streams is exported in the form of humic...

  6. Brain MR spectroscopy in children with a history of rheumatic fever with a special emphasis on neuropsychiatric complications

    International Nuclear Information System (INIS)

    Alkan, Alpay; Kutlu, Ramazan; Kocak, Gulendam; Sigirci, Ahmet; Emul, Murat; Dogan, Selda; Aslan, Mehmet; Sarac, Kaya; Yakinci, Cengiz

    2004-01-01

    Purpose: To investigate whether there are metabolite changes in basal ganglia of children with complete healing of rheumatic fever (RF), history of Syndenham chorea (SC) and obsessive compulsive-tic disorder (OCTD) developed after RF when compared with healthy controls and each other. Material and methods: A total of 49 children with history of RF and 31 healthy controls were included into the study. All patients and control group underwent a detailed neuropsychiatric evaluation. Children with the history of RF were classified into three groups as; group 1: with history of RF without neuropsychiatric complications (NCRF), group 2: only with history of SC (HSC), group 3: with HSC and OCTD (OCTD). After MR imaging, single voxel MR spectroscopy was performed in all subjects. Voxels (15x15x15 mm) were placed in basal ganglia. N-acetyl aspartate (NAA)/creatin (Cr), and choline (Cho)/Cr ratios were calculated. Results: OCTD were detected in 13 children with HSC. NAA/Cr ratio was found to be decreased in these children when compared with NCRF (n:29), HSC without OCTD (n:7) and control groups (n:31). No significant difference was found in metabolite ratios of children with HSC without OCTD when compared with NCRF and control groups. There were no significant differences in Cho/Cr ratio between patient and control groups. Conclusion: Although MR imaging findings was normal, MR spectroscopy findings (decreased NAA/Cr ratio) in our study support the neuronal loss in basal ganglia of children with OCTD and could indicate the development of permanent damage

  7. The Promotion of Employment and Earning Opportunity of Women in Europe through Gender Mainstreaming. With Special Emphasis on Austria

    OpenAIRE

    Biffl, Gudrun

    2008-01-01

    The European Union has developed a complex strategy and policy coordination process to promote gender equality in all community policies through "gender mainstreaming". While every member country has to promote the policy objective of gender equality, the instruments implemented to that end may differ. Different institutional structures and gender roles in the society may result in different outcomes of the same policy measure. Therefore every country has to choose those instruments best fitt...

  8. Volatile compounds in the perirenal fat from calves finished on semiextensive or intensive systems with special emphasis on terpenoids

    Directory of Open Access Journals (Sweden)

    Soto, S.

    2015-12-01

    Full Text Available Grazing ruminants and their production systems have been associated with lower environmental impact and higher animal welfare, along with distinctive meat quality characteristics when compared to intensively reared animals. Recent studies have been aimed at finding compounds in ruminant meat and fat which could be used as tracers of herbage feeding. This study determined and compared the volatile composition of the perirenal fat from Tudanca-breed calves reared on semi-extensive (SE; n=8 or intensive (I; n=8 systems. The volatile compounds of perirenal fat were analyzed using simultaneous distillation-extraction and gas chromatography coupled with mass spectrometry (GC/MS with the mass spectra detector operating in full scan mode. Terpenes were also determined using solid-phase micro-extraction and GC/MS operating in the selective ion monitoring mode. The SE system resulted in decreased levels of octanal, 2-octenal and 2,4-decadienal, and increased levels of 2,3-octanedione and skatole. The levels of α-pinene, aromadendrene, α-phellandrene, eucalyptol and α-gurjunene were higher for the SE system. Fenchene, eucalyptol and α-gurjunene have not been reported in previous studies on beef volatiles. The study showed the possibility of using several terpenes of perirenal fat as indicators of pasture-feeding in Tudanca calves.La producción de rumiantes en pastoreo puede suponer un menor impacto ambiental y un mayor bienestar animal, y considerarse como una característica de calidad diferenciada de la carne generada, con respecto a los animales producidos de forma intensiva. En estudios recientes se ha investigado sobre la presencia de compuestos en la carne o grasa de rumiantes que puedan ser utilizados como marcadores de alimentación a base de pasto. En el presente estudio se ha determinado y comparado la composición volátil de la grasa perirrenal de terneros de raza Tudanca criados mediante un sistema semi-extensivo (SE; n=8 o intensivo (I; n=8. Los compuestos volátiles de grasa perirrenal fueron analizados utilizando un método de extracción-destilación simultánea seguido por cromatografía de gases acoplada a un detector de espectro de masas (CG/EM, operando en modo de barrido completo. Por otra parte, se determinaron de forma específica los terpenoides utilizando la técnica de microextracción en fase solida seguida por CG/EM, operando en modo de barrido selectivo de iones. La grasa del sistema SE mostró menores niveles de octanal, 2-octenal y 2,4-decadienal y mayores niveles de 2,3-octanodiona y escatol que el sistema I. Además, los niveles de α-pineno, aromadendreno, α-felandreno, eucaliptol, α-gurjuneno fueron más altos en el sistema SE. La presencia de fencheno, eucaliptol y α-gurjuneno no ha sido descrita en estudios previos en compuestos volátiles en carne o grasa de bovino. Este estudio muestra la posibilidad de utilizar varios terpenos presentes la grasa perirrenal como indicadores de alimentación en pastoreo en terneros Tudancos.

  9. THE ROLE OF LIBRARIES IN THE DEVELOPMENT OF CULTURAL TOURISM WITH SPECIAL EMPHASIS TO THE BIBLIOTHECA ALEXANDRINA IN EGYPT

    Directory of Open Access Journals (Sweden)

    Sanja Lazarevic

    2010-12-01

    Full Text Available Cultural tourism has grown rapidly in the past few decades as a result of more income, higher levels of education, globalization processes that make the world a smaller place, technology, the effects of media and telecommunications and new types of cultural attractions. Libraries, as cultural institutions, may contribute significantly to the development of cultural tourism. One good example is the role of Bibliotheca Alexandrina in Egypt.

  10. The future energy supply in Germany in a common Europe with special emphasis on the role of nuclear power

    International Nuclear Information System (INIS)

    Kopp, G.

    2003-01-01

    The decision by the red-green federal government to opt out of the use of nuclear power has considerable consequences for the power industry and the national economy of Germany. In addition, there are additional burdens resulting from the Renewable Energies Act and the Cogeneration Act. Besides economic aspects, there are ecological benefits to be considered in favor of nuclear power. In addition to renewable energy sources, it is one of the important sources of energy which are free from CO 2 emissions. In opt-out decision also jeopardizes the role of Germany as a partner in international cooperation, with an acknowledged standard of nuclear know-how and a cutting-edge position in technical safety. The approaches towards a future energy supply system were put into specific terms together with the CDU/CSU within the activities of the parliamentary committee of inquiry on 'sustainable Energy Supply Under Conditions of Globalization and Deregulation'. The growing dependence on external energy sources, and the goals of climate protection, are other important tasks of future energy policy within the European framework. The Green Book by the EU Commission constitutes a remarkable basis for discussion in this respect. Current problems connected with nuclear power should be discussed seriously in order for nuclear power to continue successfully to contribute to energy supply in Europe. (orig.) [de

  11. Viruses in wild European fishes and their significance for aquaculture, with special emphasis on viral haemorrhagic septicamia virus

    DEFF Research Database (Denmark)

    Skall, Helle Frank

    2004-01-01

    Viral hæmorrhagisk septikæmi virus (VHSV) er en af de vigtigste virale patogener i opdrættet regnbueørred (Oncorhynchus mykiss) i Europa. Det Europæiske Fællesskabs (EU's) fiskehelse lovgivning (Direktiv 91/67/EEC) opregner VHS som en kategori 2 sygdom, hvilket er defineret som en sygdom med stor...... økonomisk betydning for Fællesskabet. VHSV er i det sidste 1½ årti blevet isoleret fra et stadig stigende antal fritlevende marine fiskearter. Indtil nu er VHSV blevet isoleret fra 46 forskellige fiskearter på den nordlige halvkugle (USA, Canada, Japan og Europa), heraf 15 forskellige fritlevende marine...... opdrættet pighvar var patogene for pighvar. Helt (Coregonus lavaretus) er blevet mistænkt for at overføre VHSV til opdrættede fisk. For at undersøge dette blev 148 vilde helt fanget i Skjern Å i december, når helten svømmer opstrøms fra Ringkøbing Fjord for at gyde. Der blev ikke isoleret virus fra helt...

  12. Predictive modelling of chromium removal using multiple linear and nonlinear regression with special emphasis on operating parameters of bioelectrochemical reactor.

    Science.gov (United States)

    More, Anand Govind; Gupta, Sunil Kumar

    2018-03-24

    Bioelectrochemical system (BES) is a novel, self-sustaining metal removal technology functioning on the utilization of chemical energy of organic matter with the help of microorganisms. Experimental trials of two chambered BES reactor were conducted with varying substrate concentration using sodium acetate (500 mg/L to 2000 mg/L COD) and different initial chromium concentration (Cr i ) (10-100 mg/L) at different cathode pH (pH 1-7). In the current study mathematical models based on multiple linear regression (MLR) and non-linear regression (NLR) approach were developed using laboratory experimental data for determining chromium removal efficiency (CRE) in the cathode chamber of BES. Substrate concentration, rate of substrate consumption, Cr i , pH, temperature and hydraulic retention time (HRT) were the operating process parameters of the reactor considered for development of the proposed models. MLR showed a better correlation coefficient (0.972) as compared to NLR (0.952). Validation of the models using t-test analysis revealed unbiasedness of both the models, with t critical value (2.04) greater than t-calculated values for MLR (-0.708) and NLR (-0.86). The root-mean-square error (RMSE) for MLR and NLR were 5.06 % and 7.45 %, respectively. Comparison between both models suggested MLR to be best suited model for predicting the chromium removal behavior using the BES technology to specify a set of operating conditions for BES. Modelling the behavior of CRE will be helpful for scale up of BES technology at industrial level. Copyright © 2018 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  13. Antimicrobial Resistance and the Alternative Resources with Special Emphasis on Plant-Based Antimicrobials—A Review

    Directory of Open Access Journals (Sweden)

    Harish Chandra

    2017-04-01

    Full Text Available Indiscriminate and irrational use of antibiotics has created an unprecedented challenge for human civilization due to microbe’s development of antimicrobial resistance. It is difficult to treat bacterial infection due to bacteria’s ability to develop resistance against antimicrobial agents. Antimicrobial agents are categorized according to their mechanism of action, i.e., interference with cell wall synthesis, DNA and RNA synthesis, lysis of the bacterial membrane, inhibition of protein synthesis, inhibition of metabolic pathways, etc. Bacteria may become resistant by antibiotic inactivation, target modification, efflux pump and plasmidic efflux. Currently, the clinically available treatment is not effective against the antibiotic resistance developed by some bacterial species. However, plant-based antimicrobials have immense potential to combat bacterial, fungal, protozoal and viral diseases without any known side effects. Such plant metabolites include quinines, alkaloids, lectins, polypeptides, flavones, flavonoids, flavonols, coumarin, terpenoids, essential oils and tannins. The present review focuses on antibiotic resistance, the resistance mechanism in bacteria against antibiotics and the role of plant-active secondary metabolites against microorganisms, which might be useful as an alternative and effective strategy to break the resistance among microbes.

  14. A review of steam explosions with special emphasis on the Swedish and Finnish BWRs. APRI 4, Phase 2 Report

    Energy Technology Data Exchange (ETDEWEB)

    Sehgal, B.R.; Haraldsson, H.O.; Yang, Z.L. [Sehgal Konsult, Stockholm (Sweden)

    2002-04-01

    The objective of the present study is to perform a critical review of ex-vessel steam explosion in Swedish and Finnish reactor containments in a hypothetical severe accident. The review performed is related to a broader program funded by APRI whose focus is related to severe accidents. A critical review of the current knowledge base on the subject is performed, including those results obtained from other studies and assessments conducted earlier under auspice of APRI. Several limiting mechanisms which may significantly impact the assessment of steam explosion loads are identified, taking into account specific reactor-design features and accident progression scenarios. In addition, generic discussion is provided on the effect of melt physical properties on the steam explosion energetics. Thermal hydraulic conditions of pre-mixture and its explosivity are evaluated using models and methods developed by the researchers at Royal Institute of Technology (RIT). The report includes a wealth of information on details with respect to quantification of vessel melt sources for ex-vessel FCIs; and with respect to the models of steam explosion premixing, triggerability and explosivity employed in the present assessment. These and other models e.g. on vessel failure, melt jet fragmentation etc. are products of the continuing research conducted at the Division of Nuclear Power Safety at RIT. The general conclusion of the present study can be summarized as: Though substantial progress have been made in premixing research verifying the mixing limit concept, there is still a need to improve jet breakup models and validate the existing models against melt jet experiments. The understanding of the triggering mechanisms is still very pool. Though various analytical models have been developed based on the thermal detonation concepts, the need still exists in both experimental and analytical research to understand better the droplet fragmentation during the explosion or propagation phase, to develop and/or improve fine fragmentation models, and to assess these models for use in reactor applications. The effects of a steam explosion of large or small yield on the debris coolability have been assessed, a low-porosity deep debris bed, which may be hard to cool, may be generated. An engineering assessment of the steam explosion energetics has been performed. The assessment covers a broader scope of scenarios of ex-vessel FCIs, i.e. including metallic-melt release scenarios. Results of the assessment indicate that the dynamic-loadings resulting from ex-vessel steam explosions in the ABB BWR plants may be smaller than the values predicted in a previous assessment.

  15. NATO Advanced Research Wokshop “Recent Trends in Energy Security: With Special Emphasis on Low-Dimensional Functional Materials”

    CERN Document Server

    Matrasulov, Davron; Rakhimov, Khamdam; Low-Dimensional F unctional Materials

    2013-01-01

    Maintaining and improving energy security is one of the biggest challenges worldwide.  The NATO ARW conference in Tashkent, October 2012, was devoted to discussing visions and concepts that are currently discussed in different research fields. Leading scientists have written concise contributions to introduce the reader to this exciting topic.  The present volume summarizes the discussions at the conference.

  16. 75 FR 55803 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epi-Centers...

    Science.gov (United States)

    2010-09-14

    ... aforementioned meeting: Time and Date 8 a.m.-5 p.m., November 8, 2010 (Closed). Place: Sheraton Gateway Hotel..., pursuant to Public Law 92-463. Matters To Be Discussed: The meeting will include the initial review...

  17. Global financial crisis and its impact in the countries in transition – with special emphasis in Kosovo

    OpenAIRE

    Halil Kukaj; Anera Alishani

    2017-01-01

    Financial crises are characterized as phenomena that have been recorded for a long time. These phenomena are considered as bad events because they are associated with a deep decline in economic activity, and many of them are considered to happen due to the lack of central banks, lack of a strong currency or the lack of a steady banking system (reduction of money supply and narrowing of loans). The first financial crisis of the modern world related to the real existence of the market and its o...

  18. Exercise effects on bone mineral density in older men: a systematic review with special emphasis on study interventions.

    Science.gov (United States)

    Kemmler, W; Shojaa, M; Kohl, M; von Stengel, S

    2018-04-05

    This systematic review detected only limited positive effects of exercise on bone mineral density in older men. Further, based on the present literature, we were unable to suggest dedicated exercise prescriptions for this male cohort that might differ from recommendations based on studies with postmenopausal women. The primary aim of this systematic review was to determine the effect of exercise on bone mineral density (BMD) in healthy older men. A systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement included only randomized or non-randomized controlled trials of exercise training ≥ 6 months with study groups of ≥ eight healthy men aged 50 years or older, not using bone-relevant pharmacological therapy, that determined BMD by dual-energy X-ray absorptiometry. We searched PubMed, Scopus, Web of Science, Cochrane, Science Direct, and Eric up to November 2016. Risk of bias was assessed using the PEDro scale. We identified eight trials with 789 participants (PEDro-score, mean value 6 of 10) which satisfied our eligibility criteria. Studies vary considerably with respect to type and composition of exercise. Study interventions of six trials were considered to be appropriate for successfully addressing BMD in this cohort. Between-group differences were not or not consistently reported by three studies. Three studies reported significant exercise effects on BMD for proximal femur; one of them determined significant differences between the exercise groups. None of the exercise trials determined significant BMD effects at the lumbar spine. Based on the present studies, there is only limited evidence for a favorable effect of exercise on BMD in men. More well-designed and sophisticated studies on BMD in healthy older men have to address this topic. Further, there is a need to define intervention quality standards and implement a universal scoring system that allows this pivotal determinant to be addressed much more intensively.

  19. Phylogeny, diversity and host specialization in the phylum Synergistetes with emphasis on strains and clones of human origin.

    Science.gov (United States)

    Marchandin, Hélène; Damay, Audrey; Roudière, Laurent; Teyssier, Corinne; Zorgniotti, Isabelle; Dechaud, Hervé; Jean-Pierre, Hélène; Jumas-Bilak, Estelle

    2010-03-01

    Members of the phylum Synergistetes have been demonstrated in several environmental ecosystems and mammalian microflorae by culture-independent methods. In the past few years, the clinical relevance of some uncultivated phylotypes has been demonstrated in endodontic infections, and uncultured Synergistetes have been demonstrated in human mouth, gut and skin microbiota. However, Synergistetes are rarely cultured from human samples, and only 17 isolates are currently reported. Twelve members of Synergistetes isolated in the course of various infectious processes, including 3 Jonquetella anthropi, 2 Cloacibacillus evryensis, 2 Pyramidobacter piscolens and 5 unidentified strains, as well as 56 clones obtained by specific PCR from the normal vaginal microflora, were studied. 16S rRNA gene-based phylogeny showed that the clones were grouped into 3 clusters, corresponding to the genus Jonquetella, P. piscolens and one novel Synergistetes taxon. The presence and diversity of Synergistetes were reported for the first time in the vaginal microflora. Synergistetes were found in healthy patients, suggesting that they could play a functional role in human microflorae, but may also act as opportunistic pathogens. Studying the phylogenetic relationships between environmental and mammalian strains and clones revealed clearly delineated independent lineages according to the origin of the sequences. Copyright 2010 Elsevier Masson SAS. All rights reserved.

  20. Progesterone signaling mediated through progesterone receptor membrane component-1 in ovarian cells with special emphasis on ovarian cancer.

    Science.gov (United States)

    Peluso, John J

    2011-08-01

    Various ovarian cell types including granulosa cells and ovarian surface epithelial cells express the progesterone (P4) binding protein, progesterone receptor membrane component-1 (PGRMC1). PGRMC1 is also expressed in ovarian tumors. PGRMC1 plays an essential role in promoting the survival of both normal and cancerous ovarian cell in vitro. Given the clinical significance of factors that regulate the viability of ovarian cancer, this review will focus on the role of PGRMC1 in ovarian cancer, while drawing insights into the mechanism of PGRMC1's action from cell lines derived from healthy ovaries as well as ovarian tumors. Studies using PGRMC1siRNA demonstrated that P4's ability to inhibit ovarian cells from undergoing apoptosis in vitro is dependent on PGRMC1. To confirm the importance of PGRMC1, the ability of PGRMC1-deplete ovarian cancer cell lines to form tumors in intact nude mice was assessed. Compared to PGRMC1-expressing ovarian cancer cells, PGRMC1-deplete ovarian cancer cells formed tumors in fewer mice (80% compared to 100% for controls). Moreover, the number of tumors derived from PGRMC1-deplete ovarian cancer cells was 50% of that observed in controls. Finally, the tumors that formed from PGRMC1-deplete ovarian cancer cells were about a fourth the size of tumors derived from ovarian cancer cells with normal levels of PGRMC1. One reason for PGRMC1-deplete tumors being smaller is that they had a poorly developed microvasculature system. How PGRMC1 regulates cell viability and in turn tumor growth is not known but part of the mechanism likely involves the regulation of genes that promote cell survival and inhibit apoptosis. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. Unraveling the microbiota of teat apices of clinically healthy lactating dairy cows, with special emphasis on coagulase-negative staphylococci.

    Science.gov (United States)

    Braem, G; De Vliegher, S; Verbist, B; Piessens, V; Van Coillie, E; De Vuyst, L; Leroy, F

    2013-03-01

    Swab samples (n=72) obtained from the teat apex of lactating dairy cows without visual signs of inflammation (n=18) were gathered on 2 well-managed Flemish dairy herds (herds 1 and 2) during the same month to assess the bacterial diversity of teat apices before milking. A combination of both culture-dependent [plating and (GTG)(5)-PCR fingerprinting of the colonies] and culture-independent [denaturing gradient gel electrophoresis (PCR-DGGE)] techniques indicated that the teat apices contain a wide diversity of bacterial genera. Despite a low bacterial load, 20 bacterial genera of 3 phyla (Actinobacteria, Firmicutes, and Proteobacteria) were present. The most prevalent bacteria were the coagulase-negative staphylococci (CNS), encompassing a total of 15 species, which were identified to the species level using a combination of (GTG)(5)-PCR fingerprinting, gene sequencing (16S ribosomal RNA and rpoB genes), and a novel PCR-DGGE technique based on the tuf-PCR amplicon. Overall bacterial diversity did not differ significantly between the herds or between noninfected and subclinically infected quarters in herd 1. In herd 1, borderline significant lower CNS species diversity was found on teat apices of noninfected quarters compared with subclinically infected quarters. The most prevalent CNS species were Staphylococcus haemolyticus and Staphylococcus equorum in both herds and Staphylococcus carnosus in herd 2. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  2. A survey of patients dose management in computed tomography with special emphasis to paetriatric patients in Ghana

    International Nuclear Information System (INIS)

    Inkoon, S.; Emi-Reynolds, G.; Boadu, M.; Schandorf, C.

    2010-01-01

    A survey of the frequency of common computed tomography (CT) examinations and the doses of six (6) CT facilities in Ghana has been undertaken. The technique factors for both adult and paediatric examinations were assessed. The dosimetric parameter used was the weighted computerized tomography dose index (CTDIw) for a single slice and the dose length product (DLP) for complete CT examinations of chest, chest high resolution (HR), lumbar spine, abdomen and pelvis. The effective dose (E) was estimated to give the stochastic radiation risk of a non-uniform exposure in terms of a whole body exposure. It was observed that some facilities used the same adult CT technique factors for paediatric patients. Mean values of adult CTDIw ranged as: chest (7.1-29.7 mGy), chest HR (7.1-30.0 mGy), lumbar spine (13.4-42.4 mGy), abdomen (7.8-42.4 mGy) and pelvis (8.9-42.4 mGy). Mean paediatric CTDIw values ranged as: chest (6.4-29.7 mGy), chest HR (6.4-30.0 mGy), lumbar spine (10.1-42.4 mGy), abdomen (10.1-42.4 mGy) and pelvis (10.1-42.4 mGy). The mean adult DLP values ranged as: chest (178-594 mGy cm), chest HR (168-594 mGy cm), lumbar spine (287-848 mGy cm), abdomen (233-848 mGy cm) and pelvis (228-848 mGy cm). However the mean paediatric DLP values ranged as: chest (128-594 mGy cm), chest HR (113-594 mGy cm), lumbar spine (253-848 mGy cm), abdomen (146-848 mGy cm) and pelvis (202-848 mGy cm). The E values for adults ranged as follows: chest (3.0-10.1 mSv), chest HR (2.9-10.1 mSv), lumbar spine (4.3-12.7 mSv), abdomen (3.5-12.7 mSv) and pelvis (4.3-12.7 mSv). The results show some agreement with diagnostic reference levels of CTDIw DLP and E values from literature. Nevertheless, further optimisation studies are needed to further reduce patient doses and modifications of technique factors especially for paediatrics (author)

  3. Comparative Roughness Characteristics of the Subducting Seafloor and Statistical Relationships with Seismogenic Potential, with Special Emphasis on Great Earthquakes

    Science.gov (United States)

    Lallemand, S.; Peyret, M.; van Rijsingen, E.; Arcay, D.

    2017-12-01

    Do some topographic features or morphological characteristics promote earthquake nucleation, large coseismic slip or creep ? To answer this question, we have developed a new database called "SubRough" which provides few roughness parameters at selected spatial wavelengths. Since the currently subducting topography is generally unknown, we assume that the bathymetry of the oceanic plates, a few hundreds of km seaward of the trench, is a reasonable proxy for determining the roughness of the subduction interface. Given the selected wavelengths in our roughness study (detailed below), we do not expect major changes when entering the subduction zone, even though the presence of a subduction channel or significant sediment offscrapping may alter it. Morphological objects characterized by high spatial frequencies (isolated seamounts or fracture zones) are likely to play a role in large events initiation or termination. Similarly, wide "smooth" areas may likely favor rupture propagation and thus large events, while ridges or plateaus may also play a specific role in seismic behavior. Consequently, we only retain the roughness components Rsw and Rlw that are comprised respectively within 2 wavelength bands: [12-20 km] and [80-100 km]. The choice of these wavelengths is constrained by the resolution of the bathymetry, the size of the studied area and the characteristic wavelengths of the seafloor topography. This new morphological information is then statistically analyzed to better understand how topographic features are modeled by roughness data. From a worldwide statistical point of view, fracture zones show similar amplitudes as mean seafloor at both wavelengths, which indicates that it is not possible to distinguish them from the background signal. Conversely, seamounts show roughness amplitudes about two times larger than the averaged ones at both wavelengths. Ridges and plateaus show Rlw amplitudes similar to seamounts but lower Rsw than seamounts. Finally, the roughness information is confronted to the spatial characteristics of earthquakes (epicenter location, slip distribution) along all subduction zones. We observe that most M>8.3 subduction earthquakes occurred in areas characterized by low Rsw and Rlw.

  4. Analysis of the development of land use in the Morava River floodplain, with special emphasis on the landscape matrix

    Directory of Open Access Journals (Sweden)

    Kilianová Helena

    2017-03-01

    Full Text Available The results of an analysis of land use development in the Morava River floodplain (Czech Republic using GIS from 1836 to the present, are the subject of this article. The results are based on the analysis of historical maps, using the landscape matrix assessment of the Morava River floodplain. The final analyses were processed from land use maps of the floodplain at a scale of 1 : 25,000 in five time horizons. These maps were compared with the present state of landscape by GIS methods. The study area was assessed according to five geomorphological areas from the northern/higher part to the southern/lower part of floodplain. In 1836 the landscape matrix of the floodplain was composed of meadows and forests. Forest components decreased minimally but the changes are more important. The grassland area (meadows and pastures decreased but arable land, as well as settlements, increased very significantly. In the 1950s the landscape matrix was composed of a mosaic of alluvial forests, meadows and arable land. Currently, the predominant landscape matrix consists of arable land and isolated forest complexes.

  5. In vitro gastrointestinal digestion study of a novel bio-tofu with special emphasis on the impact of microbial transglutaminase

    Science.gov (United States)

    Xing, Guangliang; Rui, Xin; Jiang, Mei; Xiao, Yu; Guan, Ying; Wang, Dan

    2016-01-01

    We have developed a novel bio-tofu, made from mixed soy and cow milk (MSCM), using Lactobacillus helveticus MB2-1 and Lactobacillus plantarum B1-6 incorporated with microbial transglutaminase (MTGase) as coagulant. MTGase was added to improve the textural properties and suit for cooking. However, the effect of MTGase on the digestion of mixed-protein fermented by lactic acid bacteria was unclear. This study aimed at evaluating the effect of MTGase on protein digestion of bio-tofu under simulated gastrointestinal digestion condition. The results showed that addition of MTGase could affect the particle size distribution, degree of hydrolysis, the content of soluble proteins and free amino acids. Based on the electrophoresis data, MTGase addition enhanced protein polymerization. During gastric and intestinal digestion process, proteins from bio-tofu were degraded into low molecular mass peptides. Our results suggested that incorporation of MTGase could lead to enzymatic modification of proteins of bio-tofu which may help in controlling energy intake and decrease the chance of food allergy. PMID:27994970

  6. Analysis of papers in the journal of Korean radiologic society of recent three years with special emphasis on citation index

    International Nuclear Information System (INIS)

    Yang, Seoung Oh; Choi, Sang Hee; Jeong, Cheol Hwe; Lee, Yung Il

    1990-01-01

    The papers in the Journal of the Korean Radiologic Society (JKRS) during recent three years were surveyed by analysis of their types, topics, organs, employed modalities, and cited literatures. Citation analysis is a method of studying interrelationships between papers and journals, and the most important application of citation analysis is in studies of science policy and research evaluation to evaluate the implementation of science policy and to monitor research performance. Using these citation analysis to map the journal communications network may indicate to more efficient scientific progress. Total number of papers published by JKRS for recent 3 years was 473 papers (Clinical : 354, Case report : 91, Experimental : 26, Educational : 2). The most common organ system of the papers was abdomen (head and neck, chest, musculoskeletal, cardiovascular, and urologic system in the order of decreasing frequency). The most popular topic was techniques including newer modalities and interventional radiology, and normal measurement, tuberculosis, hepatoma, normal anatomy and the like followed. Total number of cited references was 8,642 (18.26 per one paper), and the average number of authors per paper was 4.83. The most frequently used modality was CT (41%) followed by simple radiography, ultrasonogram, fluoroscopic study, angiography, nuclear imaging, and MRI. Using this kind of analysis as a guide for writing a paper for the JKRS, it could be well-organized and uplifted in its format and contents

  7. The remarkable endemism of moths at White Sands National Monument in New Mexico, USA, with special emphasis on Gelechioidea (Lepidoptera

    Directory of Open Access Journals (Sweden)

    Eric H. Metzler

    2014-03-01

    Full Text Available The white sands formation, a snow-white gypsum dunes system, is the world's largest gypsum dune field. White Sands National Monument protects about 40% of the dunes; the dunes formation as it is known today was formed ca. 8,000 years BP. Prior to 8,000 years BP, the area covered by the dunes was a wet cool forest of the last glacial maximum in North America. The dunes were formed as a result of the hypsithermal, a warming and drying period which followed the most recent glacial maximum. The white sands formation is located in south central New Mexico in the Tularosa Basin of southwestern United States. A 10-year study of moths at the dunes was commissioned by the U. S. National Park Service in 2006. Almost immediately species new to science were detected. In the period of 6 years, 30 new species were discovered in the dunes. Several of the new species are white or very pale in color, and are endemic to the dunes. The focus of the 10 year project was modified to emphasize naming the undescribed species which helps the National Park Service catalog and manage the habitats. The data should encourage other researchers to explore the interactions of the animals with the plants and the harsh desert environment, to study DNA and evolution, and to study the rapid adaptation which seems to be occurring.

  8. Regulation of Pulmonary Vascular Tone in Health and Disease: Special emphasis on exercise and pulmonary hypertension after myocardial infarction

    NARCIS (Netherlands)

    B. Houweling (Birgit)

    2007-01-01

    textabstractHigh bloodpressure in the pulmonary circulation is called pulmonary hypertension (PH). In patients with PH, the balance between vasodilators and vasoconstrictors is disturbed. PH is an important cause of death; it is characterized by elevated levels of pulmonary artery pressure

  9. LWR mox fuel experience in Belgium and France with special emphasis on results obtained in BR3

    International Nuclear Information System (INIS)

    Bairiot, H.; Haas, D.; Lippens, M.; Motte, F.; Lebastard, G.; Marin, J.F.

    1986-09-01

    The course of the paper reflects two main topics: LWR MOX fuel experience in Belgium and France, summarizing the fabrication techniques, the references, the underlying MOX fuel technology and the current R and D programs for expanding the data base; behaviour of MOX fuel rods irradiated under steady state and transient operating conditions, focusing on MOX fuel technology features acquired through the irradiations performed in the BR3 PWR, supplemented by tests in the BR2 MTR. This paper focuses on the thermomechanical behaviour of LWR MOX fuel rods, which is intimately related to the fabrication technique and vice-versa. 22 refs

  10. Spondarthritis hyperostotica pustulo-psoriatica - Review and a clinical-radiological study with special emphasis on SAPHO syndrome

    International Nuclear Information System (INIS)

    Schilling, F.; Kessler, S.

    1998-01-01

    Spondarthritis hyperostotica pustulo-psoriatica (Spond.hyp.pp-Schilling), corresponding nosologically to pustulotic arthroosteitis, is a dermato-skeletal 'double system' disease of adults. It consists of the triad (a) palmo-plantar pustulosis (Ppp) or, alternatively, Koenigsbeck-Barber-type psoriasis, (b) sternocostoclavicular hyperostosis (SCCH), and (c) truncal-skeletal changes with syndesmophite-like, hyperostotic and/or parasyndesmophite-like ossifications of layers of the anterior vertebral ligament taken together in the sense of a desmophytal hyperostosis. There is also a potential for sclerosing inflammatory arthritis of the sacro-iliac joints and 'dry' inflammatory arthritis of the sacro-iliac joints and 'dry' inflammatory arthritis of peripheral joints. Thus, the pustulo-psoriatic terrain seems to have a decisive influence on osseous pathology. A total of 38 cases from a study during the years 1982 to 1992 is analysed with regard to morphological characteristics. Rare cases with diaphyseal and pelvic hyperostotic lesions subsequent to bland sclerosing osteomyelitis constitute an overlapping region to chronic recurrent multifocal osteomyelitis (CRMO) and illustrate the relationship between hyperostotic spondarthritis and CRMO. The syndromes of 'acquired hyperostosis' and 'SAPHO', the former more radiologically oriented and the latter more clinically oriented, together with mainly CRMO and hyperostotic spondarthritis and its forms, constitute the 'Spond.hyp.pp.'. Although hyperostosis is a guidepost for the radiologist and SAPHO symptoms are one for the clinician, the syndrome does not represent a diagnosis by itself and requires further differentiation. In this report the entity 'Spond.hyp.pp.' is considered and requires contributions from rheumatologically and osteologically oriented radiologist. (orig.) [de

  11. Seasonal rhythms of body temperature in the free-ranging raccoon dog (Nyctereutes procyonoides) with special emphasis on winter sleep.

    Science.gov (United States)

    Mustonen, Anne-Mari; Asikainen, Juha; Kauhala, Kaarina; Paakkonen, Tommi; Nieminen, Petteri

    2007-01-01

    The raccoon dog (Nyctereutes procyonoides) is the only canid with passive overwintering in areas with cold winters, but the depth and rhythmicity of wintertime hypothermia in the wild raccoon dog are unknown. To study the seasonal rhythms of body temperature (T(b)), seven free-ranging animals were captured and implanted with intra-abdominal T(b) loggers and radio-tracked during years 2004-2006. The average size of the home ranges was 306+/-26 ha, and the average 24 h T(b) was 38.0+/-dogs were hypothermic for 5 h in the morning (06:00-11:00 h), whereas the highest T(b) values were recorded between 16:00-23:00 h. The range of the 24 h oscillations increased by approximately 0.6 degrees C, and the rhythmicity was more pronounced than in the snow-free period. The ambient temperature and depth of snow cover were important determinants of the seasonal T(b) rhythms. The overwintering strategy of the raccoon dog resembled the patterns of winter sleep in bears and badgers, but the wintertime passivity of the species was more intermittent and the decrease in the T(b) less pronounced.

  12. Longer-term domestic supply problems for nonrenewable materials with special emphasis on energy-related applications

    International Nuclear Information System (INIS)

    Goeller, H.E.

    1980-01-01

    An examination is made on how materials are used in present and future energy production and use. Problem areas which are discussed include by-products production, import limitations, substitution and recycle, accelerated use, synthesis, and the adequacy of the data bases availability

  13. Computed tomographic features of polyostotic craniofacial fibrous dysplasia with special emphasis on cyst-like osteolytic appearance

    International Nuclear Information System (INIS)

    Kise, Yoshitaka; Ariji, Yoshiko; Gotoh, Masakazu; Izumi, Masahiro; Naitoh, Munetaka; Ariji, Eiichiro

    2011-01-01

    The objective of this study was to clarify CT image features of the craniofacial bones in patients with polyostotic fibrous dysplasia (FD). Five patients in our hospital and 32 patients in 27 previously reported studies were selected for this study. CT image features were evaluated by 3 maxillofacial radiologists and classified into 3 patterns (sclerotic, mixed, and cyst-like lytic patterns). The bones affected by FD were the sphenoid bone, maxilla, zygoma, temporal bone, mandible, and so on. There was a significant difference in the distribution of CT image patterns by the type of bone (p=0.0012). A lytic pattern was frequently found in the mandible, sphenoid bone, frontal bone, and maxilla. The clinical data significantly affected by the distribution of CT image patterns were the periods of symptoms and the anamnesis about the previous operation: when the symptoms were persistent, the ratio of the lytic pattern was high. There was a significant difference in pattern distribution in the frontal bone and maxilla in the surgical anamnesis. No significant difference was seen by age and sex. The cyst-like lytic area was shown to be a mucocele or aneurysmal bone cyst in the frontal and sphenoid bones, whereas an inflammatory change in the jaw bones. There was a significant difference in the distribution of CT image patterns by the types of craniofacial bones affected by polyostotic FD. (author)

  14. Evaluation critique of state of the art dyslipidemia management in general and with a special emphasis on the Indian population.

    Science.gov (United States)

    Whayne, Thomas F

    2007-01-01

    Classically, there have been three well established major cardiovascular risk factors, hypercholesterolemia, hypertension and tobacco abuse. With accumulating clinical evidence, diabetes can now be added as a fourth major risk factor. Much interest in various other risk factors and possible causative factors has been generated, but it should be remembered that of all these, low density lipoproteins (LDL) remains the gold standard for evaluating risk. The common perception is that only caucasians in the western world have significant cardiovascular (CV) risk. However, much clinical information to the contrary has accumulated and now it is realized that many other ethnic groups also have significant CV disease, such as in India, especially in the urban population. Dyslipidemias of specific lipoproteins and their treatment is an important part of understanding and managing CV disease and risk. Various plasma factors such as homocysteine and lipoprotein (a) [(a)] have been considered to have definite associations with CV disease, but any treatment benefit remains in doubt. In addition, inflammatory risk factors are considered to be of significant clinical interest, especially high sensitivity C-Reactive protein (hsCRP). Where do these factors fit into routine clinical practice still awaits clarification. Only two of these inflammatory risk (Lp-factors can be tested commercially on a routine clinical basis and these are hsCRP and Lipoprotein-associated Phospholipase A2 Lp-PLA2). Their clinical utillity is not established and acceptance is limited: some third party health coverage organizations refuse to pay for such analyses. In the past, women have been looked upon as not having significant CV disease. More recently, evidence suggests that women may have more CV disease than men, and that physicians may have failed to realize this and act accordingly. The true situation is that women have less CV disease than men prior to menopause and then they slowly catch up. However, some women under age 50 have an especially malignant form of CV disease and in these cases, myocardial infarction mortality is twice that of men. The explanation and management is the subject of much clinical investigation. In both India and the western world, perhaps the most important medical problem is the metabolic syndrome (MS) and this combination of CV risk factors multiplies the significance of each. For the difficult patient not tolerant of or sufficiently responsive to conventional therapy, alternative diets and medications can frequently offer just enough benefit in lowering LDL to allow the patient to attain their target level. Future treatments undoubtedly will involve genetics, but for now, aggressive medication use can favorably modify risk although not eliminate it.

  15. Analysis of the development of land use in the Morava River floodplain, with special emphasis on the landscape matrix

    Czech Academy of Sciences Publication Activity Database

    Kilianová, H.; Pechanec, V.; Brus, J.; Kirchner, Karel; Machar, I.

    2017-01-01

    Roč. 25, č. 1 (2017), s. 35-48 ISSN 1210-8812 Institutional support: RVO:68145535 Keywords : historical maps * land use changes * floodplain * Morava River * Czech Republic Subject RIV: DE - Earth Magnetism, Geodesy, Geography OBOR OECD: Physical geography Impact factor: 2.149, year: 2016 http://www.geonika.cz/mgr.html#articles

  16. A Framework for Generalized Conjugate Gradient Methods - with Special Emphasis on Contributions by Rüdiger Weiss

    Czech Academy of Sciences Publication Activity Database

    Gutknecht, M. H.; Rozložník, Miroslav

    2002-01-01

    Roč. 41, - (2002), s. 7-22 ISSN 0168-9274 R&D Projects: GA AV ČR IAA1030103; GA ČR GA101/00/1035 Institutional research plan: AV0Z1030915 Keywords : sparse linear systems * Krylov space method * orthogonal residual method * minimal residual method * conjugate gradient method * residual smoothing * CG * CGNE * CGNR * CR * FOM * GMRES * PRES Subject RIV: BA - General Mathematics Impact factor: 0.504, year: 2002

  17. A review of steam explosions with special emphasis on the Swedish and Finnish BWRs. APRI 4, Phase 2 Report

    International Nuclear Information System (INIS)

    Sehgal, B.R.; Haraldsson, H.O.; Yang, Z.L.

    2002-04-01

    The objective of the present study is to perform a critical review of ex-vessel steam explosion in Swedish and Finnish reactor containments in a hypothetical severe accident. The review performed is related to a broader program funded by APRI whose focus is related to severe accidents. A critical review of the current knowledge base on the subject is performed, including those results obtained from other studies and assessments conducted earlier under auspice of APRI. Several limiting mechanisms which may significantly impact the assessment of steam explosion loads are identified, taking into account specific reactor-design features and accident progression scenarios. In addition, generic discussion is provided on the effect of melt physical properties on the steam explosion energetics. Thermal hydraulic conditions of pre-mixture and its explosivity are evaluated using models and methods developed by the researchers at Royal Institute of Technology (RIT). The report includes a wealth of information on details with respect to quantification of vessel melt sources for ex-vessel FCIs; and with respect to the models of steam explosion premixing, triggerability and explosivity employed in the present assessment. These and other models e.g. on vessel failure, melt jet fragmentation etc. are products of the continuing research conducted at the Division of Nuclear Power Safety at RIT. The general conclusion of the present study can be summarized as: Though substantial progress have been made in premixing research verifying the mixing limit concept, there is still a need to improve jet breakup models and validate the existing models against melt jet experiments. The understanding of the triggering mechanisms is still very pool. Though various analytical models have been developed based on the thermal detonation concepts, the need still exists in both experimental and analytical research to understand better the droplet fragmentation during the explosion or propagation phase, to develop and/or improve fine fragmentation models, and to assess these models for use in reactor applications. The effects of a steam explosion of large or small yield on the debris coolability have been assessed, a low-porosity deep debris bed, which may be hard to cool, may be generated. An engineering assessment of the steam explosion energetics has been performed. The assessment covers a broader scope of scenarios of ex-vessel FCIs, i.e. including metallic-melt release scenarios. Results of the assessment indicate that the dynamic-loadings resulting from ex-vessel steam explosions in the ABB BWR plants may be smaller than the values predicted in a previous assessment

  18. Fine structure of the midgut epithelium in the millipede Telodeinopus aoutii (Myriapoda, Diplopoda) with special emphasis on epithelial regeneration.

    Science.gov (United States)

    Rost-Roszkowska, M M; Kszuk-Jendrysik, M; Marchewka, A; Poprawa, I

    2018-01-01

    The midgut of millipedes is composed of a simple epithelium that rests on a basal lamina, which is surrounded by visceral muscles and hepatic cells. As the material for our studies, we chose Telodeinopus aoutii (Demange, 1971) (Kenyan millipede) (Diplopoda, Spirostreptida), which lives in the rain forests of Central Africa. This commonly reared species is easy to obtain from local breeders and easy to culture in the laboratory. During our studies, we used transmission and scanning electron microscopes and light and fluorescent microscopes. The midgut epithelium of the species examined here shares similarities to the structure of the millipedes analyzed to date. The midgut epithelium is composed of three types of cells-digestive, secretory, and regenerative cells. Evidence of three types of secretion have been observed in the midgut epithelium: merocrine, apocrine, and microapocrine secretion. The regenerative cells of the midgut epithelium in millipedes fulfill the role of midgut stem cells because of their main functions: self-renewal (the ability to divide mitotically and to maintain in an undifferentiated state) and potency (ability to differentiate into digestive cells). We also confirmed that spot desmosomes are common intercellular junctions between the regenerative and digestive cells in millipedes.

  19. Global financial crisis and its impact in the countries in transition – with special emphasis in Kosovo

    Directory of Open Access Journals (Sweden)

    Halil Kukaj

    2017-07-01

    Full Text Available Financial crises are characterized as phenomena that have been recorded for a long time. These phenomena are considered as bad events because they are associated with a deep decline in economic activity, and many of them are considered to happen due to the lack of central banks, lack of a strong currency or the lack of a steady banking system (reduction of money supply and narrowing of loans. The first financial crisis of the modern world related to the real existence of the market and its own capitalism as the system emerged in 1636 in the Netherlands, known as the tulip crisis, a flower symbolizing the Netherlands. Later, during the period of the first industrial revolution in England and France, dozens of crises emerged. While in the US, the first industrial crisis emerged in 1819, followed by many to the Great Depression crises of 1929-1933. According to the researchers, all these crises have occurred for the same cause: financial speculation is neglected in order to benefit as much as possible. From such a fact, one can think that crises and monetary illusions are an inevitable fatality. They have been co-drivers of development and capitalism, so it does not seem strange that most of the books and studies determined to financial crises end with the question: What is the next crisis???

  20. The regulation of glucose transport in the heart of control and diabetic rats: With special emphasis on the glucose transporter

    International Nuclear Information System (INIS)

    Pleta, M. de Leoz.

    1989-01-01

    Glucose transport regulation with insulin and high perfusion pressure in the perfused rat hearts from control and diabetic rat hearts was investigated. [ 3 H]-cytochalasin B binding assay was used to study the distribution of glucose transporters within the subcellular membranes fractionated by linear sucrose density gradient centrifugation. In the present study, insulin increased glucose uptake in the perfused heart of control and diabetic animals. This coincided with an increase of glucose transporters on the plasma membrane. The increase in glucose transporters on the plasma membrane could not be accounted for by a decrease of glucose transporters from the microsomal membranes. High perfusion pressure did not change the number of glucose transporters on the plasma membrane compared to basal in the control and diabetic animals, though it increased glucose uptake above that observed for insulin in the control. Instead, high perfusion pressure altered the distribution of glucose transporters within the subcellular membranes in reverse to that with insulin, increasing an intermediate membrane pool believed to reside between the plasma membrane and microsomal membranes as well as the intracellular membrane pool

  1. Evaluation of canola seeds of different cultivars with special emphasis on the quantification of erucic acid and glucosinolates

    Directory of Open Access Journals (Sweden)

    Anwar, Farooq

    2009-03-01

    Full Text Available This study reports the characterization of the seeds and seed oils of five locally grown canola cultivars: Zafar-2002, Bulbul (Frontier, Dunkeld, Oscar and Con-11. The oil contents from canola seeds ranged from 34.3 to 39.3%. The levels of protein, fiber, ash and moisture were found to be 22.1-41.0, 12.0-14.0, 3.0-3.5 and 4.0-7.5%, respectively. The glucosinolate (GSL contents in the canola seeds examined ranged from 49.7 to 78.1 mmol g-1. The extracted canola seed oils revealed an iodine value of 118.2-124.6 g of I/100g of oil; refractive index (40 °C, 1.460-1.464; density (24 °C, 0.914-0.919 mg m-1; saponification value, 187-195; unsaponifiable matter, 0.51-1.10%; acidity (% as oleic acid, 0.40-1.40, and color (1-in. cell, 1.35-1.73 R + 21.0-38.0 Y. Peroxide value (meq/ kg of oil and specific extinctions at 232 and 270 nm were determined to be 2.00-7.08, 2.17-3.16 and 0.44-0.91, respectively. The seed oils of the five canola cultivars mainly consisted of oleic (C18:1, linoleic (C18:2 and linolenic (C18:3 acids at levels of 49.16-62.14, 14.61, 23.45 and 6.97-9.10%, respectively. The concentrations of palmitic (C16:0, stearic (C18:0, erucic (C22:1 and gadoleic (C20:1 acids ranged from 3.47 to 6.00, 1.51 to 2.10, traces to 13.03 and 1.30 to 10.63%, respectively. A small amount of arachidic acid (20:0 with a contribution below 1% was also detected. The contents of tocopherols (α, γ, and δ in the canola oils accounted for 77.1-270.3, 191-500, 3.5-15.6 mg kg-1, respectively.The presence of rather high levels of erucic acid and GSL in the present analysis of canola emphasized the need to further reduce the contents of these two antinutritional constituents in the investigated cultivars.Este estudio describe de la caracterización de semillas y de sus aceites de cinco cultivos locales de canola: Zafar2002, Bulbul (Frontier, Dunkeld, Oscar y Con 11. El contenido de aceite de las semillas de canola varió entre un 34.3 y un 39.3%. Los niveles de proteína, fibra, ceniza y humedad fueron 22.1-41.0, 12.0-14.0, 3.0-3.5 and 4.0-7.5%, respectivamente. El contenido de glucosinolatos (GSL en las semillas de canola examinadas varió entre un 49.7 y un 78.1 mmol g-1. El aceite de canola extraído tuvo un índice de yodo de 118.2-124.6 g de I/100g de aceite; índice de refracción (40°C, 1.460-1.464; densidad (24°C, 0.914-0.919 mg mL–1; índice de saponificación, 187-195; materia insaponifiable, 0.51-1.10%; acidez (% como ácido oleico, 0.40-1.40, y color (cubeta de 1 pulgada, 1.35-1.73 R + 21.0-38.0 Y. El índice de peróxido (meq/ kg de aceite y la extinción específica a 232 and 270 nm fueron 2.00-7.08, 2.17-3.16 and 0.440.91, respectivamente. El aceite de las semillas de los cinco cultivos de canola contenían principalmente ácido oleico (C18:1, ácido linoleico (C18:2 and ácido linolenico (C18:3 a unos niveles de 49.16-62.14, 14.61-23.45 and 6.97-9.10%, respectivamente. Las concentraciones de ácido palmítico (C16:0, ácido esteárico (C18:0, ácido erúcico (C22:1 y ácido gadoleico (C20:1 variaron entre 3.47 y 6.00, 1.51 y 2.10, trazas y 13.03, y 1.30 y 10.63%, respectivamente. Una pequeña cantidad de ácido araquídico (20:0 con una contribución por debajo del 1% fue también detectada. El contenido de tocoferoles (α, γ, y δ en los aceites de canola fue de 77.1-270.3, 191-500, 3.5-15.6 mg kg-1, respectivamente. La presencia de niveles relativamente altos de ácido erúcico y GSL en el presente análisis de la canola incide en la necesidad de reducir el contenido de estos dos constituyentes anti-nutricionales en los cultivares investigados.

  2. Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review.

    Science.gov (United States)

    Kämmerer, Peer W; Schneider, Daniel; Schiegnitz, Eik; Schneider, Sarah; Walter, Christian; Frerich, Bernhard; Kunkel, Martin

    2016-09-01

    Odontoma-separated into complex (CxOD) and compound (CpOD) subtypes-represents the most frequent odontogenic malformation. Retention of permanent teeth is a common symptom. Therefore, in a series of odontomas, an analysis of the management of retained teeth was conducted. In a retrospective multicenter study of two University Medical Centers and one private praxis in Germany, demographic and clinical data regarding odontomas from 01/2000-03/2015 were obtained. In particular, the influence of operative therapy on the dentition and on the treatment of impacted teeth was analyzed. Forty-five patients with 15 CxOD and 30 CpOD were included. Initial symptoms were delayed eruption of permanent teeth (n = 11), pain (n = 4), and swellings (n = 2); 28 cases were discovered by incidence, all of them via panoramic radiographs. The mandible/maxilla ratio was about 1:0.55 (29/16). Thirty-five out of 45 odontomas were in close proximity of at least one tooth (n = 16 at molars). A total of 14 teeth were extracted (CxOD: n = 5; CpOD: n = 9). Extractions had to be conducted more often in older patients (mean age 39.8 vs. 25.6 years). Of the non-extracted teeth, 8 teeth were displaced and retained. Of those, 4 teeth were aligned in the dental arch via orthodontic help and 2 teeth erupted spontaneously after operation during the follow-up period. In all cases, no relapse was seen. Odontomas can cause displacement as well as malformation and resorption of the adjacent teeth. Mostly, removal of odontomas is conducted. Extirpation of odontoma can allow for normal tooth eruption, often rendering extractions avoidable. Orthodontic alignment, though sometimes challenging, is a reasonable therapeutic option. These findings underline the value of the panoramic radiograph in preventive dentistry in younger patients.

  3. Petroleum systems modelling of the Muensterland Basin and Ruhr Basin with special emphasis on unconventional gas resources

    Energy Technology Data Exchange (ETDEWEB)

    Uffmann, A.K.; Littke, R. [RWTH Aachen Univ. (Germany). Inst. of Geology and Geochemistry of Petroleum and Coal

    2013-08-01

    A 3D petroleum system model was built for the area of the northern Rhenish Massif and Muensterland/Ruhr Basin in order to reconstruct burial and temperature histories as well as petroleum generation and storage. The basin contains numerous potential unconventional gas reservoirs, i.e. more than 100 Pennsylvanian (Westphalian and upper Namurian) coal seams and several black shales of Pennsylvanian and Mississippian age. The focus here is on the Upper Alum Sahle ('Hangende Alaunschiefer') representing the uppermost Mississippian.

  4. System Dynamic Modelling for a Balanced Scorecard: With a Special Emphasis on Skills, Customer Base, and WIP

    DEFF Research Database (Denmark)

    Nielsen, Steen; Nielsen, Erland Hejn

    -and-effect relationships between financial and non-financial performance measures, attention should also be paid to the definitions and the number of indicators. Originality/value - A large number of case studies and surveys are now present in BSC literature. However, there is a lack of more theoretical and analytical...

  5. The molecular phylogeny of Matthiola R. Br. (Brassicaceae) inferred from ITS sequences, with special emphasis on the Macaronesian endemics.

    Science.gov (United States)

    Jaén-Molina, Ruth; Caujapé-Castells, Juli; Reyes-Betancort, Jorge Alfredo; Akhani, Hossein; Fernández-Palacios, Olga; de Paz, Julia Pérez; Febles-Hernández, Rosa; Marrero-Rodríguez, Aguedo

    2009-12-01

    Matthiola (Brassicaceae) is a genus that is widespread in the Mediterranean and Irano-Turanian regions and includes two species that are endemic to the archipelagos of Madeira and the Canaries in Macaronesia, which is an insular oceanic hotspot of biodiversity harboring many radiating endemic plant lineages. Sequence analyses of the nuclear ITS-1 and ITS-2 regions in a comprehensive geographical sample of Matthiola, encompassing all the endemic Macaronesian populations known to date, suggest independent Mediterranean and NW African origins of the taxa in Madeira and the Canaries, respectively. These molecular data reveal a complex evolutionary landscape that converges with morphological analyses in the recognition of two new Madeiran species. The data also suggest that the Canarian infra-specific endemic taxa described thus far have high (but non-diagnostic) levels of morphological and genetic diversity, and should be included in the single endemic Matthiola bolleana. In agreement with earlier investigations that revealed a high genetic differentiation between the populations of Matthiola in Fuerteventura and Lanzarote, our phylogeny supports independent founder events from the same mainland congener to either island. The consistently derived position of the Moroccan populations within a mostly Canarian clade suggests a further back-colonization of the continent. Notably, the ITS sequence resolution offered by Matthiola is higher than that found in many of the radiating Canarian endemic lineages for which molecular phylogenetic studies abound. Hence, our research discovers largely unexplored pathways to understand plant diversification in this oceanic insular hotspot through the investigation of non-speciose endemics.

  6. The Significance and Impact of Innovation Networks of Academia and Business with a Special Emphasis on Work-Based Learning

    Directory of Open Access Journals (Sweden)

    Hogeforster Max A.

    2014-10-01

    Full Text Available The Europe 2020 Strategy puts the quality and relevance of education and training systems at the heart of EU’s efforts to improve innovation and competitiveness and to achieve intelligent, sustainable and inclusive growth. The development of partnerships between vocational schools or higher-education institutions and the business sector must be considered as a critical factor in identifying learning requirements, improving the relevance of education and facilitating access to education and learning. The growing lack of skills is one of the major challenges for companies that rely on more highly qualified personnel. To increase the cooperation between academia and the business world means to integrate small and medium-sized enterprises (SMEs, since 99.2 per cent of European businesses are SMEs. They are the blood cells of the European economy and are essential for growth, yet a very heterogeneous group that can only be integrated in cooperation networks by intermediate organisations which tackle the needs of this diverse group of businesses. Such a partnership of 17 universities and polytechnics, including the University of Latvia, was founded in 2010 and is shortly introduced as a best practice example.To stay competitive in the globalised world, companies need to be innovative and that requires cooperation with knowledge institutions. A survey conducted in 2013 revealed that one of the major obstacles for SMEs to improve their innovation capabilities is their inability to find qualified personnel. This corresponds to the huge challenges the labour markets face in Europe. Almost all countries report a growing lack of skilled workforce while at the same time youth unemployment is increasing. This gap between the current qualifications and the qualifications demanded by businesses sector can be overcome by a closer cooperation between enterprises and education facilities, on a national but also international level between Western and Eastern countries. The introduction of work-based education plays a crucial role in narrowing this divide.

  7. The radiological impacts of uranium mill tailings - a review with special emphasis on the tailings at Ranstad in Sweden

    International Nuclear Information System (INIS)

    Snihs, J.O.; Agnedal, P.O.

    1978-07-01

    The environmental impact of uranium mill tailings can be expressed in collective dose commitment and corresponding detriment per MWsub(e).Y energy produced by the uranium which corresponds to the amount of waste of interest. The methods of dose commitment calculations are discussed and it is suggested for the purpose of estimation of the detriment to limit the commitment to 10,000 years. The external radiation from the tailings is easily reduced by covering but in case of a future settlement on the tailings the collective dose commitment will be some hundreds to thousands of manrad/MWsub(e).Y depending on the quality of the uranium ore. The dispersion of dust from uncovered tailings is mainly a local problem and the collective dose commitment for critical tissues in the lung will be less than a manrad/MWsub(e).Y. In the long run the cover may be lost and the resultant collective dose commitment for the critical tissues in the lung will be a few tens of manrad/MWsub(e).Y depending on the quality of the tailings. The effects of global dispersion of the material in the tailings are also discussed

  8. Intensive-care unit lung infections: The role of imaging with special emphasis on multi-detector row computed tomography

    International Nuclear Information System (INIS)

    Romano, Luigia; Pinto, Antonio; Merola, Stefanella; Gagliardi, Nicola; Tortora, Giovanni; Scaglione, Mariano

    2008-01-01

    Nosocomial pneumonia is the most frequent hospital-acquired infection. In mechanically ventilated patients admitted to an intensive-care unit as many as 7-41% may develop pneumonia. The role of imaging is to identify the presence, location and extent of pulmonary infection and the presence of complications. However, the poor resolution of bedside plain film frequently limits the value of radiography as an accurate diagnostic tool. To date, multi-detector row computed tomography with its excellent contrast resolution is the most sensitive modality for evaluating lung parenchyma infections

  9. Introduction to special relativity. 2. ed.

    International Nuclear Information System (INIS)

    Rindler, W.

    1991-01-01

    This book is intended for undergraduates taking an introductory course on special relativity that is rather more conceptually and mathematically than experimentally oriented. A suitably prepared reader could also use it for self-study. It assumes no prior knowledge of relativity. Thus it elaborates the underlying logic, dwells on the subtleties and apparent paradoxes, and also contains a large collection of problems which should just about cover all the basic modes of thinking and calculating in special relativity. Much emphasis has been laid on developing the student's intuition for space-time geometry and four-tensor calculus; but the approach is not so dogmatically four-dimensional that three-dimensional methods are rejected out of hand when they yield a result more directly. This updated new edition contains additional problems and applications, and several sections have been substantially rewritten, among them those on the Lorentz transformation and on continuum mechanics. (author)

  10. Pattern of Morbidity and Mortality in Kurdistan / Iraq with an Emphasis on Exposure to Chemical Weapon

    International Nuclear Information System (INIS)

    Dizaye, K.; Jaff, H.

    2007-01-01

    A cross-sectional survey was carried out in kurdistan -Iraq during the period 2000-2001 to determine patterns of morbidity and mortality among kurdistan population with special emphasis on those exposed to bombs and shell injuries and chemical weapons. Kurdistan was divided in to 300 sectors; from each sector, one household was selected randomly. The total study samples were 6805 including number of the household who have died since 1935. They have a male: female ratio of 1.03:1. An interview was carried out using a special questionnaire form. The mean age of the sample was 51.5 ± 0.6 years (51.1 ± 0.75 for males and 52.9 ± 0.97 for females ) 1.5% and 2.8% of surveyed population have been exposed to non - chemical weapons (bomb and shells ) or chemical weapons , respectively; 0.23% of the alive population had cancer at the time of the study. 12.6% in the study sample were complaining from respiratory disease and 6.5 had a history of miscarriage and stillbirth. Both complaints might be attributed to expose to chemical weapons. 869 (12.5 %) of the study have died since 1935, 68.4% of them have died during the period 1980 - 1999. 3 % of all deaths were due to exposure to shells or chemical weapons; 7.9 % were lost in Al - anfal campaign in 1980s of the last century. 8.5 % of all death were due to cancer probably due to exposure to chemical weapons. (author)

  11. MEANINGFUL VARIABILITY: A SOCIOLINGUISTICALLY-GROUNDED APPROACH TO VARIATION IN OPTIMALITY THEORY

    Directory of Open Access Journals (Sweden)

    Juan Antonio Cutillas Espinosa

    2004-12-01

    Full Text Available Most approaches to variability in Optimality Theory have attempted to make variation possible within the OT framework, i.e. to reformulate constraints and rankings to accommodate variable and gradient linguistic facts. Sociolinguists have attempted to apply these theoretical advances to the study of language variation, with an emphasis on language-interna1 variables (Auger 2001, Cardoso 2001. Little attention has been paid to the array of externa1 factors that influence the patterning of variation. In this paper, we argue that some variation pattems-specially those that are socially meaningful- are actually the result of a three-grarnmar system. G, is the standard grammar, which has to be available to the speaker to obtain these variation patterns. G; is the vernacular grammar, which the speaker is likely to have acquired in his local community. Finally, G, is an intergrammar, which is used by the speaker as his 'default' constraint set. G is a continuous ranking (Boersma & Hayes 2001 and domination relations are consciously altered by the speakers to shape the appropriate and variable linguistic output. We illustrate this model with analyses of English and Spanish.

  12. A conceptual framework for evaluating variable speed generator options for wind energy applications

    Science.gov (United States)

    Reddoch, T. W.; Lipo, T. A.; Hinrichsen, E. N.; Hudson, T. L.; Thomas, R. J.

    1995-01-01

    Interest in variable speed generating technology has accelerated as greater emphasis on overall efficiency and superior dynamic and control properties in wind-electric generating systems are sought. This paper reviews variable speed technology options providing advantages and disadvantages of each. Furthermore, the dynamic properties of variable speed systems are contrasted with synchronous operation. Finally, control properties of variable speed systems are examined.

  13. Changing emphasis at the NRC's Office of Nuclear Regulatory Research

    International Nuclear Information System (INIS)

    Remick, F.J.

    1994-01-01

    One of the major objectives of the Office of Research is to ensure availability of sound technical information for timely decision making in support of the NRC's safety mission. The Office of Research is changing some of its emphasis to better meet the expected needs of the NRC's regulatory offices. Long-standing programs in support of operating reactors are nearing completion. These programs include plant aging and severe accident research for currently operating plants. This meeting will also address the new challenges faced by the NRC in its review of the advanced light water and non-light water reactors. As plant aging and severe accident research programs are nearing completion, the research activities are coming to focus on the emerging technologies, for example, digital instrumentation and control systems, both as replacement equipment for operating plants and as the technology of choice and necessity for the advanced reactors. Necessity, because analog equipment is becoming obsolete. Other examples include the use of new materials in operating plants, human factors considerations in the design and operation of the advanced plants, thermal-hydraulic characteristics of the advanced reactors, and new construction techniques

  14. Environmental factors in causing human cancers: emphasis on tumorigenesis.

    Science.gov (United States)

    Sankpal, Umesh T; Pius, Hima; Khan, Moeez; Shukoor, Mohammed I; Maliakal, Pius; Lee, Chris M; Abdelrahim, Maen; Connelly, Sarah F; Basha, Riyaz

    2012-10-01

    The environment and dietary factors play an essential role in the etiology of cancer. Environmental component is implicated in ~80 % of all cancers; however, the causes for certain cancers are still unknown. The potential players associated with various cancers include chemicals, heavy metals, diet, radiation, and smoking. Lifestyle habits such as smoking and alcohol consumption, exposure to certain chemicals (e.g., polycyclic aromatic hydrocarbons, organochlorines), metals and pesticides also pose risk in causing human cancers. Several studies indicated a strong association of lung cancer with the exposure to tobacco products and asbestos. The contribution of excessive sunlight, radiation, occupational exposure (e.g., painting, coal, and certain metals) is also well established in cancer. Smoking, excessive alcohol intake, consumption of an unhealthy diet, and lack of physical activity can act as risk factors for cancer and also impact the prognosis. Even though the environmental disposition is linked to cancer, the level and duration of carcinogen-exposure and associated cellular and biochemical aspects determine the actual risk. Modulations in metabolism and DNA adduct formation are considered central mechanisms in environmental carcinogenesis. This review describes the major environmental contributors in causing cancer with an emphasis on molecular aspects associated with environmental disposition in carcinogenesis.

  15. Bacterial biofilms with emphasis on coagulase-negative staphylococci

    Directory of Open Access Journals (Sweden)

    A Oliveira

    2008-01-01

    Full Text Available In addition to their capacity to attach to surfaces, various groups of microorganisms also produce an extracellular polymeric substance known as "slime". This slime forms a thin layer around cells known as biofilm. Thus, biofilm structure comprises bacterial cells and an extracellular polymeric substance. It also presents a defined architecture, providing the microorganisms with an excellent protective environment and favoring the exchange of genetic material between cells as well as intercellular communication. The ability to produce biofilm is observed in a large group of bacteria, including coagulase-negative staphylococci (CNS which are the predominant microorganisms of normal skin flora and have been implicated as the causative agents of hospital infections. Bacteremia caused by these agents is common in immunodepressed persons, in patients with cancer, in adult and neonatal intensive care units (ICU and in patients using catheters or other prosthetic devices. The pathogenicity of CNS infections is probably related to the production of slime, which adheres preferentially to plastic and smooth surfaces, forming a biofilm that protects against attacks from the immune system and against antibiotic treatment, a fact hindering the eradication of these infections. The main objective of the present review was to describe basic and genetic aspects of biofilm formation and methods for its detection, with emphasis on biofilm creation by CNS and its relationship with diseases caused by these microorganisms which are becoming increasingly more frequent in the hospital environment.

  16. Complex variables

    CERN Document Server

    Flanigan, Francis J

    2010-01-01

    A caution to mathematics professors: Complex Variables does not follow conventional outlines of course material. One reviewer noting its originality wrote: ""A standard text is often preferred [to a superior text like this] because the professor knows the order of topics and the problems, and doesn't really have to pay attention to the text. He can go to class without preparation."" Not so here-Dr. Flanigan treats this most important field of contemporary mathematics in a most unusual way. While all the material for an advanced undergraduate or first-year graduate course is covered, discussion

  17. Overview of experimental progress on understanding photon strength functions with an emphasis of the Oslo method

    Science.gov (United States)

    Krticka, Milan

    2015-10-01

    The so-called Photon Strength Functions (PSFs) for different multipolarities are, together with the Nuclear Level Density (NLD) the key entities describing the statistical γ-decay of nucleus. It is well known that PSFs at energies above the threshold for particle emission are well described by the Lorentzian shape of the Giant Electric Dipole Resonance (GEDR). On the other hand, shapes of RSFs at the low-energy tail of GEDR are known rather poorly. Information on the PSFs at the GEDR tail can be obtained from several different experimental techniques. They will be summarized and the most important ones briefly introduced in this contribution. Special emphasis will be put on the so-called Oslo method which allows simultaneous extraction of the NLD and the PSFs from particle- γ coincidence measurements. This method has been used for determining the NLD and the PSFs in many nuclei in A ~ 45- 240 range during past years. Examples of the most interesting results obtained with this method will be shown. The results will be compared to information on the PSFs available from other experimental techniques. The strengths and the weaknesses of the method will be thoroughly discussed.

  18. Tuberous sclerosis: Analysis of 24 cases with emphasis on atypical findings

    International Nuclear Information System (INIS)

    Lee, Eun Ju; Suh, Jung Ho; Joo, Suk Hyun; Chung, Tae Sub

    1990-01-01

    We retrospectively analysed the clinical and CT findings of 24 cases with tuberous sclerosis with special emphasis upon the atypical presentation. The cases with classic clinical triad were accounted for in 21%, while 33% presented with atypical clinical features. The most common and characteristic CT finding is that of the subependymal calcified nodules of the lateral ventricle, which was seen in 85% of our cases. Cortical tuber and white matter lesions were demonstrated in 65% and 55%, respectively. Three cases showed cortical tuber and white matter lesion without subependymal tuber. The cortical tuber usually exhibited low density or calcified lesion, but showed high density in 2 cases. Other findings of tuberous sclerosis included intraventricular tumor, ventriculomegaly, and cortical atrophy. One case clearly demonstrated parenchymal tuber on MR imaging. In conclusion, diagnosis of tuberous sclerosis is usually made on the clinical bases initially. However, CT and MR are also diagnostic even in unusual clinical presentation such as unexplained retardation or epilepsy or when the classic clinical triad is incomplete. If only cortical tuber or white matter lesion is present, it is difficult to diagnose tuberous sclerosis and to differentiate from other cortical mass lesion. Therefore, careful evaluation is required with familiarity with the atypical appearance of the disease

  19. Intellectual property considerations for molecular diagnostic development with emphasis on companion diagnostics.

    Science.gov (United States)

    Glorikian, Harry; Warburg, Richard Jeremy; Moore, Kelly; Malinowski, Jennifer

    2018-02-01

    The development of molecular diagnostics is a complex endeavor, with multiple regulatory pathways to consider and numerous approaches to development and commercialization. Companion diagnostics, devices which are "essential for the safe and effective use of a corresponding drug or diagnostic product" (see U.S. Food & Drug Administration, In Vitro Diagnostics - Companion Diagnostics, U.S. Dept. of Health & Human Services(2016), available at https://www.fda.gov/medicaldevices/productsandmedicalprocedures/invitrodiagnostics/ucm407297.htm ) and complementary diagnostics, which are more broadly associated with a class of drug, are becoming increasingly important as integral components of the implementation of precision medicine. Areas covered: The following article will highlight the intellectual property ('IP') considerations pertinent to molecular diagnostics development with special emphasis on companion diagnostics. Expert opinion/commentary Summary: For all molecular diagnostics, intellectual property (IP) concerns are of paramount concern, whether the device will be marketed only in the United States or abroad. Taking steps to protect IP at each stage of product development is critical to optimize profitability of a diagnostic product. Also the legal framework around IP protection of diagnostic technologies has been changing over the previous few years and can be expected to continue to change in the foreseeable near future, thus, a comprehensive IP strategy should take into account the fact that changes in the law can be expected.

  20. Polarimetry of magnetic catalysmic variables

    Energy Technology Data Exchange (ETDEWEB)

    Cropper, M

    1985-01-01

    The design and construction of an astronomical polarimeter is described and an evaluation made of its performance. Extensive observations of cataclysmic variables with emphasis on the AM Her and DQ Her classes are then presented. The polarimeter permitted simultaneous linear and circular polarisation measurements, or, by rearranging the order of the retarders in the beam, linear polarisation measurements alone, or circular polarisation measurements alone, with enhanced efficiency. Extensive sets of observations using the polarimeter were obtained for six of the ten AM Her variables. A comparison was made between the competing models for the cyclotron emission, showing that those which take into account the temperature structure of the accretion region provide the best results.