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Sample records for valdo kuusemets mari

  1. Sülg tuleb konkreetse inimese suhu / Valdo Randpere

    Index Scriptorium Estoniae

    Randpere, Valdo, 1958-

    2007-01-01

    IBM Eesti tegevdirektor kirjutab, et anonüümsusest vabanemiseks tuleks muuta netikommentaarid tasuliseks. Samal teemal vt. ka Postimees, 18. mai, lk. 18, Valdo Randpere "mis pekkid sul on pakks pederasd"

  2. Huvi õpilase vastu peaks olema suurem / Maria Tiro, Merilin Piipuu, Valdo Randpere, Liisa Pakosta ; küsitlenud Sigrid Kõiv

    Index Scriptorium Estoniae

    2008-01-01

    Jüri Gümnaasiumi direktor Maria Tiro, Eesti Õpilasesinduste Liidu juht Merilin Piipuu, lapsevanem ja IBM Eesti juht Valdo Randpere ning lapsevanem ja Eesti Lastevanemate Liidu esindaja Liisa Pakosta arutlesid koolivägivalla üle tänapäeva koolis

  3. Marie Curie

    National Research Council Canada - National Science Library

    Serna M., Edgar

    2011-01-01

    Maria Sklodowska--Marie Curie--fue pionera en la ciencia de la radiactividad; es mejor conocida como la descubridora de los elementos radiactivos polonio y radio, y como el primer cientifico en ganar dos premios Nobel: Fisica y Quimica...

  4. MARIE CURIE

    Directory of Open Access Journals (Sweden)

    EDGAR SERNA MONTOYA

    2011-12-01

    Full Text Available María Sklodowska ‒Marie Curie‒ fue pionera en la ciencia de la radiactividad; es mejor conocida como la descubridora de los elementos radiactivos polonio y radio, y como el primer científico en ganar dos premios Nobel: Física y Química. Para sus colegas y el público en general, el radio fue la clave para un cambio fundamental en nuestra comprensión de la materia y la energía. Su trabajo no sólo influyó en el desarrollo de la ciencia fundamental, sino que también marcó el comienzo de una nueva era en la investigación y los tratamientos médicos.

  5. Marie Sklodowska Curie

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Marie Sklodowska Curie. Articles written in Resonance – Journal of Science Education. Volume 6 Issue 3 March 2001 pp 94-96 Classics. Rays Emitted by Compounds of Uranium and of Thorium · Marie Sklodowska Curie · More Details Fulltext PDF ...

  6. Avangardistid Moskvas / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Valdek Alberi ja Taave Tuutma videoinstallatsioonist "Think different" näitusel "Salon 2000" Moskva Kunstnike Keskmajas 16.-26. III. Kuraator Mari Sobolev. Eesti väljapaneku vastukajast ja Jüri Arrakust, kelle maalid olid näitusel "Balti meistrid", ajalehes "Kommersant". Moskva kunstinäitustest.

  7. Lasteaed Naba / Maris Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2005-01-01

    Konkursil "Eesti parim puitehitis 2005" parima puitehitise tiitli pälvinud lasteaed Naba Pirital. Arhitektid Lauri Saar ja Vahur Sova. Sisearhitekt Mari Tosmin. Insener Tõnu Peipman. Ehitus: KMG Ehitus. Ill.: 2 värv. välis- ja 8 sisevaadet

  8. Queen Mary Two Step

    OpenAIRE

    Melin, Mats H.

    2007-01-01

    n/a Dance devised by Mats Melin in October 2007 whilst teaching Ceilidh dancing on board the cruise ship Queen Mary 2 crossing the Atlantic from Southampton to New York and back with the Ian Muir Sound from Prestwick. The segment of music featured is from Ian Muir Scottish Dance Band's recording of an Eva Three step.

  9. Klassika & ekskremendid / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2002-01-01

    20.-21. aprillil toimus Pärnus 8. Fideo- ja Vilmifestival alapealkirjaga "Eksperimendid ja klassika". Peakorraldaja Rael Artel. Rami Raski filmist "Legowitz 1999" (soome rühmitus Vivid), läti filmist "Love, death & television", Concordia ülikooli ("Ülemus") ja Academia Grata (portreefilmid Asta Isakist, Andrus Joonasest jm.) programmist, Kadriann Kibuse ja Liina Paakspuu filmist "Urban Obsessions", Mirja-Mari Smidti ja Allan Tõnissoo videost, Marianne Männi koomiksitest kataloogis

  10. Mary, dogma, and psychoanalysis.

    Science.gov (United States)

    Todd, E H

    1985-06-01

    Why does Mary hold her prominent place in Catholic theology to the extent that five specific dogmas have developed around her? Psychoanalytic theory suggests dogma arises out of the psychic needs of people and psychic needs of people are expressed in dogma. The early views of Erich Fromm, a disciple of Freud, are presented to demonstrate that Marian dogma arose from the psychic needs of the people. The views of both Catholic and Protestant thinkers are presented, as well as theological and psychiatric views.

  11. Robotic Software Integration Using MARIE

    Directory of Open Access Journals (Sweden)

    Carle Côté

    2006-03-01

    Full Text Available This paper presents MARIE, a middleware framework oriented towards developing and integrating new and existing software for robotic systems. By using a generic communication framework, MARIE aims to create a flexible distributed component system that allows robotics developers to share software programs and algorithms, and design prototypes rapidly based on their own integration needs. The use of MARIE is illustrated with the design of a socially interactive autonomous mobile robot platform capable of map building, localization, navigation, tasks scheduling, sound source localization, tracking and separation, speech recognition and generation, visual tracking, message reading and graphical interaction using a touch screen interface.

  12. Multistate Aquatic Resources Information System (MARIS)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — MARIS is an internet-based information sharing network that allows multiple states to provide a common set of variables via a single web interface. MARIS is not a...

  13. Marie Curie: Physicist and Woman

    Science.gov (United States)

    Howes, Ruth

    Marie Sklodowska was born in Warsaw on November 7, 1867. Girls were not allowed to attend college in Poland, so Marie found a well-paying post as a governess in rural village which she held for three years while helping her older sister complete medical school in Paris. Then Marie moved to Paris and graduated first in her class at the Sorbonne with a master's degree in physics in 1893. In 1895, she married the talented young physicist, Pierre Curie. Marie decided to investigate the radioactive components of the mineral pitchblende for her dissertation. The work involved chemical analysis of a ton of material in an unheated shed. Pierre joined her and at the end of 1898, the Curies announced the discovery of radium and polonium. Through 1899, Marie labored to measure the atomic weight of radium. In 1903, Marie earned her doctorate, the first for a woman in France, and the Curies split the Nobel Prize in Physics with Henri Becquerel. They became widely known, besieged by the press and frequently invited to make presentations and be awarded honors. They hated fame and both suffered bad health. In April, 1906, Pierre Curie was struck by a wagon and killed instantly. Marie was left as a single mother with two young daughters. Fortunately, the Sorbonne hired her to fill Pierre's position. In 1911, she was rejected for membership in the French Academy of Science because she was a woman. Also in 1911, she was accused of having an affair with a married French physicist Paul Langevin. The resulting scandal hit the press and brought angry mobs to her home. In the middle of this hullaballoo, she was informed that she had won a second Nobel Prize, this time in Chemistry. When World War I broke out, Marie mounted x-ray units on cars and became a heroine. She visited the United States in 1921 where President Harding presented her with a gram of radium. She continued her scientific studies in spite of declining health until her death in 1934. Professor Emerita.

  14. Mary Shelley: Teaching and Learning through "Frankenstein"

    Science.gov (United States)

    Girard, Theresa M.

    2009-01-01

    In the writing of "Frankenstein", Mary Shelley was able to change the course of women's learning, forever. Her life started from an elite standpoint as the child of Mary Wollstonecraft and William Godwin. As such, she was destined to grow to be a major influence in the world. Mary Shelley's formative years were spent with her father and his many…

  15. Charcot-Marie-Tooth Disease

    Science.gov (United States)

    Charcot-Marie-Tooth disease (CMT) is a group of genetic nerve disorders. It is named after the three doctors who first identified it. ... a nerve biopsy. There is no cure. The disease can be so mild you don't realize ...

  16. Mary Slessor Journal of Medicine

    African Journals Online (AJOL)

    The Mary Slessor Journal of Medicine (MJSM) publishes original research papers, review articles, case reports and short communications on any aspect of health and tropical diseases. All papers are refereed by independent assessors. Vol 9, No 1 (2009). DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT ...

  17. In Remembrance: Mary Frances Lyon

    Indian Academy of Sciences (India)

    In Remembrance: Mary Frances Lyon. (15 May 1925 – 25 December 2014). I start this piece from that day in 1969 when I first heard of the Lyon's hypothesis in the final semester of my master degree course in zoology at Banaras Hindu University in Varanasi. A lecture on evolution of sex chromosomes introduced us to.

  18. Louis Leakey and Mary Leakey

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 8. Louis Leakey and Mary Leakey: The First Family of Palaeoanthropology. Rajan Gaur. General Article Volume 20 Issue 8 August 2015 pp 667-679. Fulltext. Click here to view fulltext PDF. Permanent link:

  19. Pierre-Marie Luc Robitaille

    Directory of Open Access Journals (Sweden)

    Rabounski D.

    2011-07-01

    Full Text Available We celebrate the 50th birthday anniversary of Prof. Pierre-Marie Robitaille, the author of Progress in Physics who is one of the leading experts in the Nuclear Magnetic Reso- nance Imaging. Prof. Robitaille is known as the designer of the most world’s first Ultra High Field MRI scanner. Prof. Robitaille still continues his creative research activity in the field of thermal physics, connected to the origin of the Microwave Background and astrophysics.

  20. Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Reilly, Mary M

    2011-03-01

    Charcot-Marie-Tooth (CMT) disease is the commonest inherited neuromuscular disorder affecting at least 1 in 2,500. Over the last two decades, there have been rapid advances in understanding the molecular basis for many forms of CMT with more than 30 causative genes now described. This has made obtaining an accurate genetic diagnosis possible but at times challenging for clinicians. This review aims to provide a simple, pragmatic approach to diagnosing CMT from a clinician\\'s perspective.

  1. Mary Shelley as editor of Percy Shelley

    OpenAIRE

    Allen, Richard

    2001-01-01

    This chapter explores Mary Shelley's work as the founding editor of Percy Shelley's poetry. It sets out the circumstances of Mary Shelley's life after the death of Percy Shelley, her financial dependence on Percy Shelley's father, and the restrictions placed on publication by Shelley's father. It then sets out the strategies Mary Shelley used to construct a biography of Percy Shelley from the poem, thus establishing a Romantic biography of Percy Shelley which has endured into the 20th century,

  2. Mary and femininity: A psychological critique.

    Science.gov (United States)

    Harrington, P A

    1984-09-01

    This essay uses Freud to interpret the symbolism and theology of Mary in modern Catholicism. In her role as the mother of believers, Mary functions to place the Christian in the position of a child who receives illusory gratification from the mother. In her role as model for Christians to emulate, Mary functions to place the Christian in the position of receptivity and dependence which Freud associated with femininity. Reinterpreting Freud from a feminist perspective, I suggest that the kind of femininity Mary represents serves to perpetuate patriachal social structures and to inhibit full psychological maturity.

  3. Genetics Home Reference: Charcot-Marie-Tooth disease

    Science.gov (United States)

    ... autosomal recessive Genetic Testing Registry: Charcot-Marie-Tooth disease, demyelinating, type 1b Genetic Testing Registry: Charcot-Marie-Tooth disease, demyelinating, type 1d Genetic Testing Registry: Charcot-Marie-Tooth ...

  4. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Rotermanni soolaladu. "Elektrokardiogramm" (tegevuskunsti üritus); Vaal-galerii. Antoni T̉pies "Litograafiaid aastatest 1973-1995"; Mari Kadanik, Eero Barndõk, Rain Ader "Pildid" (maalid); Paldiski Põhikool. "Niemenlautta ja Hugo Simbergi fotod" (soome kunstniku fotode koopiad, pildistatud enne 1915. a.; Kullo lastegalerii. Neli uut näitust.(lastekunst); Arhitektuurimuuseum. Arnold Matteus - Tartu linna arhitekt (juubelinäitus), Alvar Aalto "Kolm objekti Eestis"; Linnagalerii Tallinnas. "Valge" (ruumi- ja moekunsti näitus); Sammas-galerii. Jüri Jegorow "Insect" (arvutigraafika); Endla Teatri palmisaal. "Muzik in der Kunst" (Tallinna kunstitudengite näitus); Eesti Rahvusraamatukogu. Õie Kütt "Uued ja vanad ehted"

  5. Scheuthauer-Marie-Sainton syndrome

    Directory of Open Access Journals (Sweden)

    Vikas Elias Kuruvila

    2012-01-01

    Full Text Available Scheuthauer-Marie-Sainton syndrome also known as Cleidocranial dysplasia (CCD is an autosomal dominant disorder characteristically presented with multiple supernumerary teeth; partial or complete absence of the clavicles; and open sagittal sutures and fontanelles. This condition was first reported by Meckel in 1760. There is also evidence that it existed in the prehistoric man. More than 1,000 cases have been reported in the medical literature regarding this syndrome. A case of a 35-year-male of CCD with multiple supernumerary teeth is being reported. The diagnostic and management aspects of this syndrome are discussed.

  6. Mary Anne Chambers | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    A former Member of Provincial Parliament, Mary Anne served as Minister of Training, Colleges and Universities, and Minister of Children and Youth Services in the Government of Ontario. She is also a former senior vice-president of Scotiabank. A graduate of the University of Toronto, Mary Anne has received honorary ...

  7. Charcot-Marie-Tooth disease

    Science.gov (United States)

    Sivera, Rafael; Vílchez, Juan Jesús; Martínez-Rubio, Dolores; Chumillas, María José; Vázquez, Juan Francisco; Muelas, Nuria; Bataller, Luis; Millán, José María; Palau, Fancesc; Espinós, Carmen

    2013-01-01

    Objectives: To determine the genetic distribution and the phenotypic correlation of an extensive series of patients with Charcot-Marie-Tooth disease in a geographically well-defined Mediterranean area. Methods: A thorough genetic screening, including most of the known genes involved in this disease, was performed and analyzed in this longitudinal descriptive study. Clinical data were analyzed and compared among the genetic subgroups. Results: Molecular diagnosis was accomplished in 365 of 438 patients (83.3%), with a higher success rate in demyelinating forms of the disease. The CMT1A duplication (PMP22 gene) was the most frequent genetic diagnosis (50.4%), followed by mutations in the GJB1 gene (15.3%), and in the GDAP1 gene (11.5%). Mutations in 13 other genes were identified, but were much less frequent. Sixteen novel mutations were detected and characterized phenotypically. Conclusions: The relatively high frequency of GDAP1 mutations, coupled with the scarceness of MFN2 mutations (1.1%) and the high proportion of recessive inheritance (11.6%) in this series exemplify the particularity of the genetic distribution of Charcot-Marie-Tooth disease in this region. PMID:24078732

  8. Mary Seacole: global nurse extraordinaire.

    Science.gov (United States)

    Staring-Derks, Corry; Staring, Jeroen; Anionwu, Elizabeth N

    2015-03-01

    A discussion of recently discovered literature that reveals how after the Crimean War ended in 1856, Jamaican nurse, doctress and entrepreneur Mary Seacole travelled more widely and gained further international recognition than had previously been appreciated. New findings demonstrate that Seacole's international charitable and business activities were reported more widely than realised. Recently discovered literature uncovers her networking and strategic skills in various social milieus. A former Scutari nurse and 39 other women, offered their service to Seacole to nurse British soldiers in India. Newspapers also reported the medal she had been awarded from the Turkish government. Discussion paper. Digitized 19th-century newspaper reports, and 1857 Dutch and 1858 French translations of Seacole's autobiography and a recently discovered handwritten letter dated 1 October 1857 from Seacole to Sir Henry Storks, at the time Secretary for Military Correspondence at the War Office, London. Awareness of the findings affords a more thorough understanding of the scope and diversity of nursing history. This can provide valuable role models for the 21st century generations of competent and self-confident healthcare professionals. The new evidence offers further testimony that Seacole can truly be considered as one such figurehead. British and international primary sources reveal Mary Seacole as an historical and charismatic global phenomenon, more than had been previously realised. © 2014 John Wiley & Sons Ltd.

  9. Marie Curie during ORT4

    Science.gov (United States)

    2003-01-01

    Marie Curie rover drives down the rear ramp during Operational Readiness Test (ORT) 4.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  10. Marie Curie during ORT6

    Science.gov (United States)

    2003-01-01

    Marie Curie sits on the lander petal prior to deployment during the pre launch Operations Readiness Test (ORT) 6.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  11. Jean-Marie Dufour 1937-2007

    CERN Document Server

    2007-01-01

    Jean-Marie Dufour, who was head of the CERN Legal Service from 1974 until his retirement in 2001, passed away on 8 July. Following his arrival at CERN in 1966 during the crucial phase of expansion of the Laboratory’s site, Jean-Marie Dufour ensured that CERN’s rules were applied while taking part in essential stages of the Organization’s development. With his fine mind and erudition, Jean-Marie Dufour, a staunch European devoted to the CERN cause, has left his mark on the Legal Service. The Service will publish a tribute to him in a forthcoming issue of the Bulletin.

  12. Marie Curie's heritage; L'heritage Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Pajot, Ph.; Schaeffer, A.; Barhelemy, P.

    2011-02-15

    This issue is almost entirely dedicated to Marie Curie. The first part gives the main steps of her life, an article draws a parallel with Lise Meitner's life, another describes the instruments Marie Curie used to measure radioactivity and a third one gives an idea of the network of scientists she integrated. The second part presents the scientific heritage of Marie Curie, first the curietherapy then medical imaging and radiocarbon dating. The third part presents other achievements and commitments of Marie Curie concerning the place of women in a modern society and the social changes trough scientific progress. (A.C.)

  13. Radium, Marie Curie and modern science.

    Science.gov (United States)

    Langevin-Joliot, H

    1998-11-01

    In 1898, the discovery of two new elements, polonium and radium, reawakened interest in the topic of uranic rays discovered 2 years before by H. Becquerel. Radioactivity, a name coined by Marie Curie, became a major research field for decades. The contrasting personalities of Pierre Curie, already a first-rank physicist, and of the young Marie Curie-Sklodowska as they undertook their common work are described. It is shown how a well-chosen quantitative method and a systematic approach combining physics and chemistry led to the discovery within less than 1 year. The special role of radium and the determination of its atomic weight by Marie Curie followed by her long-term program for accumulating pure radium salts are emphasized. The first woman with a full professorship at a French University, Marie Curie created and managed the Radium Institute.

  14. "Mary Hartman, Mary Hartman": An Analysis of Satire as a Violation of Soap Opera Stereotypes.

    Science.gov (United States)

    Gaulard, Joan M.

    The soap opera "Mary Hartman, Mary Hartman" presents an interesting new genre in television, as it defies the conventional standards and stereotypes associated with daytime drama. The central character is not a dependent victim but a survivor who indicates to her viewers the concept which advertisers and media management have of them. A…

  15. CHARCOT-MARIE-TOOTH DISEASE

    Directory of Open Access Journals (Sweden)

    Lea Leonardis

    2003-09-01

    Full Text Available Background. Charcot-Marie-Tooth (CMT disease is a common inherited disorder of the peripheral nervous system. In our paper, different types of CMT are described with their typical clinical pictures, electrophysiological signs and molecular genetic studies. CMT is classified as demyelinative and axonal type and distal motor neuronopathy.Conclusions. CMT can be of autosomal dominant, recessive and X-linked inheritance. The most frequent form of CMT is the result of the dominantly inherited duplication of chromosome 17p11.2 and is marked as CMT1A. The same group involves also rare patients with point mutation in the peripheral myelin protein-22 gene. CMT1B is associated with point mutations in protein zero gene. CMT1C is linked to chromosome 16p13.1–12.3. Patients with point mutations in early growth response 2 gene (EGR2 are included in group CMT1D. The disease can be also inhereted X-linked (CMTX with the mutations in connexin-32 gene. In autosomal recessive inherited demyelinating polyneuropathies (CMT4, mutations are found in the myotubularin-related protein-2 (CMT4B, N-myc downstream-regulated gene 1 (CMT4D, EGR2 (CMT4E, and in the periaksin (CMT4F genes. In axonal inherited neuropathy, mutations are found in KIF1beta (CMT2A and in light neurofilament (CMT2E genes, other forms map to different chromosomal loci (CMT2B, CMT2D, CMT2F. Some suggestions for the diagnostic procedures of patients with CMT are given.

  16. Engineering international relations / Maris Riekstins ; interv. Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Riekstins, Maris

    2008-01-01

    Läti annab peatselt Läänemeremaade Nõukogu eesistuja teatepulga üle Taanile. Läti välisminister Maris Riekstins Läänemeremaade Nõukogu teemadest ning suhetest Venemaaga. Maris Riekstins'i CV

  17. Meet EPA Scientist Marie O'Shea, Ph.D.

    Science.gov (United States)

    EPA Scientist Dr. Marie O'Shea is Region 2's Liaison to the Agency's Office of Research and Development (ORD). Marie has a background in research on urban watershed management, focused on characterizing and controlling nutrients in stormwater runoff.

  18. Remembering Mary Tyler Moore | MedlinPlus Magazine

    Science.gov (United States)

    ... Remembering Mary Tyler Moore Follow us NIH MedlinePlus Magazine Remembers Mary Tyler Moore A little more than ... helped launch the first issue of NIH MedlinePlus magazine on Capitol Hill. The award-winning actress and ...

  19. MaRIE Undulator & XFEL Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

    2015-03-23

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  20. Maris Jesse üks 34st maailma tervise-otsustajast / Maris Jesse

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    21. mail Eesti esindajana Maailma Terviseorganisatsiooni täitevkogu liikmeks kinnitatud Maris Jesse vastab küsimustele, mis puudutavad tema tööd uuel ametikohal, valitsuskriisi Eestis, suhtumist proua Evelin Ilvese meditsiiniteemalistesse seisukohtadesse

  1. Classroom Instruction: The Influences of Marie Clay

    Science.gov (United States)

    McNaughton, Stuart

    2014-01-01

    Marie Clay's body of work has influenced classroom instruction in direct and indirect ways, through large overarching themes in our pedagogical content knowledge as well as specific smart practices. This paper focuses on her the contributions to our thinking about instruction which come from two broad theoretical concepts; emergent literacy…

  2. Mary Elizabeth Hickox Mandels, 90, bioenergy leader

    Directory of Open Access Journals (Sweden)

    Eveleigh Douglas E

    2009-09-01

    Full Text Available Abstract Mary E H Mandels, who spearheaded the US Army's national bioconversion studies for four decades and was an early proponent of conversion of waste biomass to readily bioconvertible sugars for the production of chemicals and transportation fuels such as ethanol, died 17 February 2008 at Natick, MA, USA. She was 90.

  3. Bon appetite! / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis

    2009-01-01

    Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

  4. Ervin Pütsepa auhind Mari Laanemetsale

    Index Scriptorium Estoniae

    2011-01-01

    Ervin Pütsepa kunstiteaduse aastapreemia monograafia "Lääne modernismi ja nõukogude avangardi vahel. Mitteametlik kunst Eestis 1969-1978" eest. Saksakeelne monograafia põhineb Mari Laanemetsa Humboldti ülikoolis 2008. a. kaitstud doktoritööl

  5. Women in History--Mary Seacole

    Science.gov (United States)

    Harmer, Bonnie

    2005-01-01

    Born in Jamaica in 1805, Mary Seacole (nee Grant), was the daughter of a Black Creole boarding house owner and a Scottish Army officer. Like many Creole doctress women, Seacole was taught African herbal medicine arts from her mother. In addition to understanding traditional herbal medicine, she gleaned an understanding of Western medicine from the…

  6. Marie Sklodowska Curie (1867-1934)

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 3. Marie Sklodowska Curie (1867-1934). Featured Scientist Volume 6 Issue 3 March 2001 pp 98-98. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/006/03/0098-0098. Resonance – Journal of ...

  7. Navodnenija v umah zactroishtshikov / Maris Kuuda

    Index Scriptorium Estoniae

    Kuuda, Maris

    2007-01-01

    Kohalikel omavalitsustel pole piisavalt hoobasid sundida arendajaid üleujutusohuga arvestama. Pärnusse hotelli September rajajad (arhitektid Emil Urbel, Andrus Mark) arvestavad ujutusohuga. Arvamust avaldavad Rene Reisner, Mari Sepp, Ülo Sults, Karri Tiigisoon, Indrek Rannik, Mark Soosaar, Tiiu Pärn, Merle Looring, Rita Sepp, Kaspar Alles

  8. Anaesthesia and Charcot-Marie- Tooth Disease

    African Journals Online (AJOL)

    Adele

    family history of peripheral motor and sensory neuropathy that had been diagnosed as Charcot-Marie-Tooth (CMT) disease type 1. He had undergone genetic testing which showed a duplication of the peripheral myelin protein (PMP 22) gene consistent with CMT Type. 1A. The previous anaesthetic for right foot surgery was ...

  9. 667 Louis Leakey and Mary Leakey

    Indian Academy of Sciences (India)

    IAS Admin

    Resonance journal of science education. August 2015 Volume 20 Number 8. GENERALARTICLES. 667. Louis Leakey and Mary Leakey. The First Family of ... 711 Role of Outer Membrane Vesicles of Bacteria. M V Jagannadham and M K Chattopadhyay. 726 Polynomial Formula for Sums of Powers of Integers. K B Athreya ...

  10. Mari Trentinjan : Muzhtshina jejo smerti / Bernard Lavillier

    Index Scriptorium Estoniae

    Lavillier, Bernard

    2003-01-01

    Prantsuse näitlejanna Marie Trintignant'iga (41) suri 1. augustil Prantsusmaal oma elukaaslase, ansambli "Noir Desire" liidri Bertrand Cantat' poolt Vilniuses talle tekitatud trauma tagajärjel. Näitlejanna eludraama. Järgneb 5. jaan. 2004, lk. 16-18 : ill

  11. The St Marys fragmentation grenade explosion.

    Science.gov (United States)

    Nocera, A

    1997-05-19

    The accidental explosion of a fragmentation grenade in a munitions factory at St Marys injured four workers, two critically. The prompt response by ambulances and physician-staffed helicopter emergency medical service prevented deaths, but the incident suggests lessons for the future handling of urban explosions.

  12. Mary Abigail Dodge: Journalist & Anti-Feminist.

    Science.gov (United States)

    Beasley, Maurine

    Mary Abigail Dodge, a Washington, D.C., correspondent before and after the United States Civil War, was one of the most acclaimed women journalists of the nineteenth century. Unknown today, Dodge wrote on politics, religion, and contemporary issues for newspapers and magazines and commented prolifically on the role of women in society. After…

  13. Visions of Mary Wollstonecraft: Implications for Education.

    Science.gov (United States)

    Manus, Alice L.

    This paper discusses the educational and social philosophy of Mary Wollstonecraft, an English writer of the 18th century. Her works included "Vindication of the Rights of Man," and her best know work, "Vindication of the Rights of Woman" which was published in 1792 and consisted of the first sustained argument for female…

  14. Mary Somerville and the world of science

    CERN Document Server

    Chapman, Allan

    2015-01-01

    Mary Somerville (1780-1872), after whom Somerville College Oxford was named, was the first woman scientist to win an international reputation entirely in her own right, rather than through association with a scientific brother or father. She was active in astronomy, one of the most demanding areas of science of the day, and flourished in the unique British tradition of Grand Amateurs, who paid their own way and were not affiliated with any academic institution. Mary Somerville was to science what Jane Austen was to literature and Frances Trollope to travel writing. Allan Chapman’s vivid account brings to light the story of an exceptional woman, whose achievements in a field dominated by men deserve to be very widely known.

  15. Jean-Marie Dufour 1937-2007

    CERN Multimedia

    2007-01-01

    Picture taken by Rudiger Voss in the Legal Service LibraryJean-Marie Dufour, CERN Legal Advisor from 1974 until his retirement in 2001, passed away on 8 July. For us, his colleagues in the Legal Service, Jean-Marie was a tutor and a reference, who passed on to us his passion for the practice of law in an intergovernmental organisation. As a boss, his abiding managerial quality was his unstinting loyalty to his collaborators. Jean-Marie joined CERN in 1966 and for the next 35 years was to be the guardian of the Laboratory’s rules. This was his view of the Organization: "...I have discovered [at CERN] a fascinating universe driven by two forces: science and Europe; a world of physicists and engineers who, encouraged by the States of Europe, run a remarkable Laboratory, where Europeans have achieved reconciliation and restored the grand tradition of European physics, attracting physicists from around the world; a Laboratory that transcends not only the fro...

  16. Women who Worked with Marie Curie.

    Science.gov (United States)

    Pigeard-Micault, Natalie

    2015-06-01

    Marie Curie directed a research laboratory for 28 years. Between 1906 and 1934, forty five women worked under her guidance. Some were, and are, well-known in their own countries as their first woman full professor such as Ellen Gleditsch or Margaret von Wrangel, but for twenty eight of them, who were often French, nothing has ever been written. The strong presence of women in Marie Curie's laboratory has often been highlighted and has been considered as an exception, and the result of deliberate choice. Of course, these women did not choose this workplace by accident. They knew its director was a woman, a laureate of one, and after 1911, two Nobel Prizes, who was leading a well-equipped laboratory with an important radioactive source. But how did Marie Curie selected her collaborators among the many applications she received? Was her choice influenced by gender? A prosopographical research based on genealogical researches and new sources explains this presence contextually and sheds light on several questions : where did these women come from, what were their social and geographic origins, did they occupy any specific cultural or technical area inside Curie's lab, what future did they have after the laboratory? Through their lives, we can question the existence, or not, of a one profile of the female researcher in scientific areas in France.

  17. Tulnuka taassünd / Valdo Jahilo

    Index Scriptorium Estoniae

    Jahilo, Valdo, 1972-

    1998-01-01

    Mängufilm "Tulnuka taassünd" ("Alien Ressurrection"), režissöör Jean-Pierre Jeunet : USA 1997 ja sellele eelnenud tulnuka-filmid Ridley Scotti "Alien" (USA 1980), James Cameroni "Aliens" (USA 1986), David Fincheri "Alien 3" (USA 1992)

  18. Otsing küberruumis / Valdo Praust

    Index Scriptorium Estoniae

    Praust, Valdo

    1997-01-01

    Järgneb nr. 8, lk. 45-46, nr. 9, lk. 32-33 ; 1998 nr. 1, lk. 4-5, nr. 3, lk. 4-7, nr. 4, lk. 4-5, nr. 5, lk. 41-43, nr. 8, lk. 8-10. Info levitamine ja kättesaadavus Internetis: WWW, Usenet, anonüümne FTP, Lycos

  19. Marie and Pierre Curie. Life in extremes; Marie and Pierre Curie. Leben in Extremen

    Energy Technology Data Exchange (ETDEWEB)

    Roethlein, Brigitte

    2008-07-01

    In Paris in 1894, two young physicists fall in love: Marie Sklodowska and Pierre Curie. They get married and make great contributions to science, research radioactivity and discover new chemical elements. The marriage of Marie and Pierre Curie is quite modern: They work together as equals, share their thoughts and pursue their plans together as partners. They share an absolute interest in science, a love of nature, and a sceptic attitude towards the sophisticated society of the Belle Epoque. They are together 24 hours a day with hardly ever any disagreement. Whenever one of them is ill - which is quite often because of the high level of radioactivity in their laboratory -, the other will nurse him or her. After only twelve years of mutual love, Pierre Curie dies. Marie raises their two daughters on her own and continues her research. In 1911, she will be the first scientist that ever gets a second Nobel Prize. (orig.) [German] Im Paris des Jahres 1894 verlieben sich zwei junge Physiker: Marie Sklodowska und Pierre Curie. Sie heiraten und leisten gemeinsam Grosses fuer die Wissenschaft, erforschen die Radioaktivitaet und entdecken neue chemische Elemente. Zusammen erhalten sie den Nobelpreis. Marie und Pierre Curie fuehren eine Ehe, die ihrer Zeit weit voraus ist: Sie arbeiten gleichberechtigt miteinander, teilen ihre Gedanken und verfolgen ihre Plaene gemeinsam. Beiden eigen ist die absolute wissenschaftliche Neugier, die Liebe zur Natur und die Skepsis gegenueber der mondaenen Gesellschaft der Belle Epoque. Fast jeden Tag sind sie rund um die Uhr zusammen, dabei gibt es selten Spannungen. Wenn einer von beiden gesundheitliche Probleme hat - und das haben sie wegen der radioaktiven Belastung im Labor oft - ist der andere fuer ihn da und pflegt ihn. Nach nur zwoelf gemeinsamen Jahren der Liebe und Arbeit stirbt Pierre Curie. Marie zieht ihre beiden Toechter alleine gross und fuehrt die Forschungen weiter. 1911 erhaelt sie als erster Mensch zum zweiten Mal den

  20. Farewell Jean-Marie Good Luck Eva Welcome back Franz

    CERN Document Server

    2001-01-01

    At the farewell reception offered by the Director-General, Professor Luciano Maiani, on the occasion of Jean-Marie Dufour's retirement from CERN, three generations of CERN Legal Counsel met. From right to left: Jean-Marie Dufour, who retires on 30 November 2001, after 35 years of service. Eva-Maria Gröniger-Voss, who takes over from Jean-Marie Dufour on 1st December 2001. Ambassador Franz Schmid, CERN Legal Counsel from 1971 to 1974.

  1. Mari Martin - vahelüli looja ja kandja vahel / Mari Martin ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Martin, Mari, 1983-

    2009-01-01

    Kalamari Promotioni tegevjuht, Tartu Ülikoolis majandust õppiv Mari Martin oma esimestest sammudest moemaailmas, kaubamärkide ReUse RePublic (premeeriti noorte äriideede võistlusel "Ajujaht 2009" 175000 krooniga) ja Tallinn Dolls loomisest, eesti disaineritest, unistustest seoses eesti disainiga

  2. Gifts from Mary Ainsworth and John Bowlby.

    Science.gov (United States)

    Crittenden, Patricia M

    2017-07-01

    Attachment theory has developed over many decades - and continues to develop. Its roots lie in several seminal publications of John Bowlby (the basis of attachment theory) and Mary D. S. Ainsworth (the notion of individual differences in attachment). This paper identifies the prescient contributions of these early publications and two processes (a long-term dialogue and reflection on discrepancy) that underlay emergent theory. Because I was a student of Ainsworth when both attachment theory and individual differences in attachment organization were becoming better known, I offer some of my recollections of that period, suggesting how that period may have affected current work in attachment.

  3. Marie Curie's contribution to Medical Physics.

    Science.gov (United States)

    Jean-Claude, Rosenwald; Nüsslin, Fridtjof

    2013-09-01

    On occasion of its 50th anniversary, the International Organization for Medical Physics (IOMP) from now on is going to celebrate annually an International Day of Medical Physics for which the 7th November, the birthday of Marie Sklodowska Curie, a most exceptional character in science at all and a pioneer of medical physics, has been chosen. This article briefly outlines her outstanding personality, sketches her fundamental discovery of radioactivity and emphasizes the impact of her various achievements on the development of medical physics at large. © 2013 Published by Elsevier Ltd on behalf of Associazione Italiana di Fisica Medica.

  4. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  5. Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2015-01-01

    Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

  6. Marie and Pierre Curie and radium: history, mystery, and discovery.

    Science.gov (United States)

    Mould, R F

    1999-09-01

    Commencing with Marie Curie's early life in Poland and the discovery of radium in the rue l'Homond "shed" in Paris in 1898, this paper includes some little known facts. It ends with some unusual uses of and claims for radium, and finally, because Medical Physics is an American journal, details are included of Marie Curie's two visits to the USA.

  7. Marie Stopes International Child Spacing Clinics in Malawi

    African Journals Online (AJOL)

    However, about 300 million couples in the developing world still do not have access to family planning and this figure is rising by the year. MSI is working to provide family health services to help satisfy this un-met need. Marie Stopes International (MSI) in Malawi. Marie Stopes International first become involved in Malawi.

  8. Roadmap to MaRIE March 2015

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-30

    Los Alamos National Laboratory’s proposed MaRIE facility is slated to introduce the world’s highest energy hard x-ray free electron laser (XFEL). As the light source for the Matter-Radiation Interactions in Extremes experimental facility (MaRIE), the 42-keV XFEL, with bursts of x-ray pulses at gigahertz repetition for studying fast dynamical processes, will help accelerate discovery and design of the advanced materials needed to meet 21st-century national security and energy security challenges. Yet the science of free-electron lasers has a long and distinguished history at Los Alamos National Laboratory (LANL), where for nearly four decades Los Alamos scientists have been performing research, design, development, and collaboration work in FEL science. The work at Los Alamos has evolved from low-gain amplifier and oscillator FEL development to highbrightness photoinjector development, and later, self-amplified spontaneous emission (SASE) and high-gain amplifier FEL development.

  9. Moved by Mary: The power of pilgrimage in the modern world

    NARCIS (Netherlands)

    Hermkens, A.K.; Jansen, W.H.M.; Notermans, C.D.

    2009-01-01

    The Virgin Mary continues to attract devotees to her images and shrines. In Moved by Mary, anthropologists, geographers and historians explore how people and groups around the world identify and join with Mary in their struggle against social injustice, and how others mobilize Mary to impose ideas

  10. The life and legacy of Marie Curie.

    Science.gov (United States)

    Rockwell, Sara

    2003-01-01

    Marie Curie was a remarkable woman whose discoveries broke new ground in physics and chemistry and also opened the door for advances in engineering, biology, and medicine. She broke new ground for women in science: she was, for example, the first woman to receive a doctor of science degree in France, the first woman to win Nobel Prize, the first woman to lecture at the Sorbonne, the first person to win two Nobel Prizes, and the first Nobel Laureate whose child also won a Nobel Prize. Her life offers insights into the changing role of women in science and academia over the past century. It also offers examples of many ways in which scientists can, and should, work to improve the educational programs and career opportunities available to those who follow in their footsteps.

  11. Mary Anning: the fossilist as exegete.

    Science.gov (United States)

    Goodhue, Thomas W

    2005-03-01

    The fossil hunter Mary Anning began collecting her 'curiosities' at a time when the age and nature of these relics from the past were little understood. Her spectacular discoveries of prehistoric marine reptiles, fossilized fish and a pterosaur touched off a geology-mania around the world. Two documents that have escaped previous analysis cast light on the religious journey of this remarkable woman. An eight-page manuscript at the Natural History Museum in London indicates a fascination with Benjamin West's painting 'Christ Rejected' and sophistication in Biblical interpretation; and a commonplace book at the Dorset County Museum in Dorchester tracks the shift in her Christian denomination from dissent to the Established Church, providing further indication of her spiritual depth - a piety that furthered, rather than hindered, her scientific progress.

  12. Mariátegui: un marxista nietzscheano

    Directory of Open Access Journals (Sweden)

    Alfonso Ibáñez

    2001-01-01

    Full Text Available En la conmemoración de la muerte de Nietzsche, ocurrida hace un siglo, conviene tener muy en cuenta su recepción entre nosotros. Es el caso de José Carlos Mariátegui, quien desde posiciones que se podrían ver como antagónicas a las del pensador alemán, hace una asimilación original de motivos nietzscheanos dentro de su concepción revolucionaria. A tal punto que se podría decir que su “marxismo nietzscheano” es el que le posibilita la elaboración del proyecto de un “socialismo indoamericano”. ¿De la confrontación con la “filosofía del martillo” surgirán nuevas propuestas alternativas en el milenio que inauguramos?

  13. Marie Curie and Mildred Dresselhaus, inspirations to women in science

    Science.gov (United States)

    Murray, Cherry

    The physics community lost the celebrated physicist Mildred Dresselhaus on February 20, 2017. Millie was originally scheduled to give this talk describing how fascination with Marie Curie's biography propelled her into science at a young age. I will talk about the many parallels I see between the two pioneers: Marie Curie, born in 1867, who was an inspiration to a young Millie, and Millie, born in 1930, who was an inspiration to me, as well as many more women and men in science. I will also describe some of Millie's research in condensed matter physics making use of radioactivity and the heritage of Marie Curie.

  14. Mari Koger : seina sisse ehitatud akvaariumiga poissmehekodu / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    80-ruutmeetrine poissmehekorter Viimsi uues elamus. Elutoa ja vannitoa vahelises seinas paikneb kahelt poolt vaadeldav akvaarium. Magamistoa üks seintest on ehitatud vanadest tellistest. Sisearhitekt Mari Koger, tema kommentaarid. Ill.: plaan, 9 värv. vaadet

  15. Marie Curie's Doctoral Thesis: Prelude to a Nobel Prize.

    Science.gov (United States)

    Wolke, Robert L.

    1988-01-01

    Traces the life and research techniques of Marie Curie's doctoral dissertation leading to the discovery and purification of radium from ore. Reexamines the discoveries of other scientists that helped lead to this separation. (ML)

  16. Ämari baas sobib USA-le ja brittidele

    Index Scriptorium Estoniae

    2013-01-01

    Eelmisel nädalal Eestit külastanud USA ja Ühendkuningriigi sõjalised esindajad NATO juures kindralleitnandid David R. Hogg ja Christopher Harper kinnitasid, et on valmis oma lennukeid Ämari baasist opereerima

  17. A bust of Marie Sklodowska Curie at CERN

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The Polish Deputy Minister of Energy and Nuclear Power, J. Felicki, presented the Directors General with a bust of Mme Marie Sklodowska Curie on behalf of physicists of Poland (CERN Courier 19 (1979) 164).

  18. Raamatukogu esisele kerkib kevadel Marie Underi kuju / Andres Eilart

    Index Scriptorium Estoniae

    Eilart, Andres

    2009-01-01

    Skulptor Mati Karminil ja arhitekt Tiit Trummalil valmib valgest marmorist mälestusmärk Marie Underile. Kuju püstitatakse 2010. a. kevadel Eesti Rahvusraamatukogu ette. Alale on kavandatud ka veekaskaadid

  19. Exploring the Universe with John Milton and Mary Shelley.

    Science.gov (United States)

    Poston, David

    1989-01-01

    Presents an approach to teaching John Milton's "Paradise Lost" in conjunction with Mary Shelley's "Frankenstein." Notes that a study of these works stimulates vigorous discussions on theological and moral issues, human nature, and the cultural past and future. (MM)

  20. Anne-Marie Sargueil: ilu on kasulik / intervjueerinud Emilie Toomela

    Index Scriptorium Estoniae

    Sargueil, Anne-Marie

    2015-01-01

    Prantsuse Disainiinstituudi juht Anne-Marie Sargueil rääkis prantsuse ja skandinaavia disainist, prantslaste disainieelistustest, uutest suundadest disaini valdkonnas, Eesti Tarbekunsti- ja Disainimuuseumis avatud näitusest "20 prantsuse disainiikooni"

  1. Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine

    Science.gov (United States)

    ... Issues Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine Past Issues / Winter 2007 Table of Contents For ... Javascript on. Among those attending the NIH MedlinePlus magazine launch on Capitol Hill were (l-r) NIH ...

  2. Else-Marie Osmundsen: Workers' Education and the Environment.

    Science.gov (United States)

    Labour Education, 1991

    1991-01-01

    Else-Marie Osmundsen, manager of an International Labour Office project, "Workers' Education and the Environment," discusses the importance of union participation in environmental programs. She describes the implementation of the project in the Caribbean. (JOW)

  3. A jolly good call for Marie Curie Fellows

    CERN Multimedia

    2009-01-01

    A new funding opportunity to train young researchers has just been announced by the European Commission. One of the calls within FP7 Marie Curie Actions requests proposals for Initial Training Network (ITN) projects, with a deadline of 22 December 2009. Project proposals are strongly encouraged at CERN and authors can receive support and guidance from the Marie Curie Steering Group. Winnie Wong: "I wouldn’t have considered a PhD if I hadn’t been a Marie Curie fellow" Dan Savu: "It’s the best of both worlds: training plus working in an international organisation" ITN projects have one key aim: training. Academic and industrial partners work together to form a network to recruit and train Marie Curie Fellows. Fellows are young researchers (typically PhD-level) from any country who combine project-based research with tailor-made training programmes, ...

  4. ODYSSEY MARS MARIE CALIBRATED DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The MARIE (Martian Radiation Environment Experiment), aboard the 2001 Mars Odyssey spacecraft, was launched on April 7, 2001, and arrived at Mars on October 24,...

  5. Referrals to the Marie Curie nursing service in North Yorkshire.

    Science.gov (United States)

    Hanratty, B; Feather, J; Ward, C

    2000-01-01

    District and Marie Curie nurses participated in a small-scale study to describe referrals to a Marie Curie service in one English health district over a 3-month period. The number of new patients referred was small; they were geographically clustered and had widely differing life expectancies. Anecdotal reports of difficulties with the 'Nurselink' referral system were not confirmed, and in situations where the system was in operation, Marie Curie nurses were more likely to speak directly to the referring nurse. The most frequently cited reason for referral was general nursing needs; however, Marie Curie nurses felt that they were most often involved to provide family support. These findings suggest that there may not be a shared understanding of the Marie Curie nurse's role, and that equity in community palliative nursing care merits examination. Defining and publicizing the role of the Marie Curie nurse, providing guidance for referrals and prioritizing communication between professionals are proposed not only to enhance the service locally but to ensure that the service is available to all. This article illustrates the value of research to identify ways to improve service delivery.

  6. Pierre Marie: gifted intellect, poor timing and unchecked emotionality.

    Science.gov (United States)

    Goetz, Christopher G

    2003-06-01

    Pierre Marie was a prominent member of the French neurological world of the early twentieth century. Having been trained by the celebrated physician, J-M Charcot, Marie remained influenced by his teacher throughout his career. Because of this influence, his career can be logically divided into three phases: first, the early years under the direct mentorship of Charcot (1878-1893); secondly, the aftermath of Charcot's death when Marie left his teacher's institution, the Salpêtrière hospital and established himself at the Bicêtre hospital in southern Paris (1893-1918); and finally, Marie's return to the Salpêtrière to assume the original Charcot chaired professorship, albeit as an aged man (1918-1925). This essay examines Marie's career with an emphasis on documentation of the combined attributes of a gifted intellect as well as a heated emotionality. In the context of his time, these elements prompted Marie to enter into controversies and medico-political battles that advanced neurological knowledge, but likely disadvantaged him in his career successes.

  7. Põhja-Eesti Regionaalhaigla X-korpus = North-Estonian Regional Hospital X-wing / Mari Kurismaa ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2011-01-01

    Tallinnas Sütiste tee 19 asuva haigla juurdeehitise sisekujundusest. Sisearhitekt Mari Kurismaa (Stuudio Kurismaa OÜ). Arhitektid Indrek Suigusaar, Vivian Oruvee (AB Pluss OÜ). Infograafika autor Mari Kaljuste

  8. Jean-Marie Dufour receives the Legion of Honour

    CERN Multimedia

    2001-01-01

    French Ambassador Philippe Petit (left) presents the cross of Knight of the Légion d'Honneur to Jean-Marie Dufour. On Friday 22 June, Jean-Marie Dufour, Head of CERN's Legal Service, was made Knight of the Legion of Honour by Ambassador Philippe Petit, at a ceremony held at the Permanent Mission of France in Geneva. Ambassador Petit is Permanent Representative of France at the United Nations and French delegate at CERN. He was awarded the decoration in recognition of his services. He has played an active part in all the great stages of CERN's development, in fact, ranging from its scientific programmes, to its establishment in its Host States, Switzerland and France, and its opening up to the wider world. The ceremony took place in the presence of Professor Luciano Maiani. The award is an honour to CERN, and the Organization takes this opportunity to convey its friendliest congratulations to Jean-Marie Dufour, a committed European.

  9. [Marie Heiberg. Üks naine kurbade silmadega] / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    2010-01-01

    Arvustus: Heiberg, Marie. Üks naine kurbade silmadega : Eesti luuletaja Marie Heibergi õnne ja valu, rõõmu ja mure lugu kirjades / [koostajad Iivi Lepik, Kirsten Simmo]. Tallinn : Eesti Teatri- ja Muusikamuuseum : SE & JS, 2010

  10. Sister Mary Joseph nodule: it does not bode well

    Directory of Open Access Journals (Sweden)

    Stephen A. Geller

    2014-09-01

    Full Text Available Sister Mary Joseph, the superintendent nurse and surgical assistant of Dr. William Mayo at St Mary’s Hospital (presently Mayo Clinic, was the first to note the association of umbilical nodules with intra-abdominal malignancy. Dr. Hamilton Bailey, a British surgeon, in his classic book Physical Signs in Clinical Surgery named the lesion for Sister Mary Joseph; the palpable bulging usually firm nodule distorting and invading into the umbilicus as a manifestation of metastatic malignancy from the abdomen or the pelvis.

  11. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology

    CERN Multimedia

    Patrice Loiez

    2002-01-01

    Photo 0210004_1: Prof. Ugo Amaldi, University of Milano Bicocca and Tera Foundation, Italy. Addressing the Marie Curie Workshop held at CERN 3-4 October 2002. Title of this talk:"Research Developments on Medical Physics". Photo 0210004_2: Marie Curie Fellows at CERN. Participating in Marie Curie Workshop held at CERN 3-4 October 2002.

  12. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s):. 2016-08-14 to 2016-08-23. Destination(s):. Peru/Colombia. Airfare: $3,484.87. Other. Transportation: $0.00. Accommodation: $1,942.21. Meals and. Incidentals: $395.27. Other: $75.50. Total: $5,897.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the.

  13. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Purpose: Represent IDRC at Rideau Hall event. Date(s):. 2017-06-05. Destination(s):. Ottawa. Airfare: $788.71. Other. Transportation: $0.00. Accommodation: $0.00. Meals and. Incidentals: $0.00. Other: $0.00. Total: $788.71. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary.

  14. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Purpose: Internal IDRC meetings. Date(s):. 2016-07-06. Destination(s):. Ottawa. Airfare: $482.11. Other. Transportation: $64.30. Accommodation: $0.00. Meals and. Incidentals: $25.28. Other: $0.00. Total: $571.69. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the.

  15. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Purpose: Board meetings. Date(s):. 2016-11-20 to 2016-11-23. Destination(s):. Ottawa. Airfare: $445.14. Other. Transportation: $29.05. Accommodation: $786.80. Meals and. Incidentals: $76.79. Other: $0.00. Total: $1,337.78. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson ...

  16. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Ottawa. Airfare: $368.41. Other. Transportation: $69.95. Accommodation: $542.79. Meals and. Incidentals: $164.42. Other: $0.00. Total: $1,145.57. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  17. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    chantal taylor

    Purpose: Board meetings. Date(s):. 2017-03-19 to 2017-03-22. Destination(s):. Ottawa. Airfare: $121.05. Other. Transportation: $51.92. Accommodation: $926.48. Meals and. Incidentals: $190.40. Other: $0.00. Total: $1,289.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor ...

  18. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  19. In Memoriam: Emerita Professor Mary Esther Kropp Dakubu | Osam ...

    African Journals Online (AJOL)

    2016-11-17

    From 2011 to 2016, she was the Editor-In-Chief of the Ghana Journal of Linguistics. She also co-edited the six volume series Studies in the Languages of the Volta Basin published by the Department of Linguistics, University of Ghana. Prof. Mary Esther Kropp Dakubu passed away on November 17, 2016, in Boston, MA, ...

  20. PARTNER: A Marie Curie Initial Training Network for hadron therapy

    CERN Multimedia

    CERN BULLETIN; Nathalie Hospital; Manuela Cirilli

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  1. MRI of congenital Foix-Chavany-Marie syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Cellerini, M. [Cattedra di Neuroraliologia, Univ. di Firenze (Italy); Mascalchi, M. [Cattedra di Radiologia, Univ. di Pisa (Italy); Salvi, F. [Div. di Neurologia, Ospedale Bellario, Bologna (Italy); Muscas, G.C. [Dipt. di Scienze Neurologiche e Psichiatriche, Univ. di Firenze (Italy); Dal Pozzo, G. [Cattedra di Neuroraliologia, Univ. di Firenze (Italy)

    1995-06-01

    MRI findings of bilateral central macrogyria allowed the diagnosis of a congenital variant of Foix-Chavany-Marie syndrome in four patients aged between 13 and 32 years, with facio-pharyngo-glosso-masticatory central diplegia, mental retardation and seizures. (orig.)

  2. Naine : masin või loom? / Maris Palgi

    Index Scriptorium Estoniae

    Palgi, Maris

    2007-01-01

    Eero Taltsi, Margus Kiisi, Maia Mölleri, Kaie Luige, Eva Orava ja Maris Palgi projektist "Maine-loom, naine-masin", mida tutvustati 2006. a. Moostes üritusel "Postsovkhoz 6", 2007. a. jaanuaris-veebruaris Tartu Kunstimajas ja Tartu Tampere Majas. Näitused avati E. Taltsi ja M. Kiisi loeng-performance'itega

  3. Charcot-Marie-Tooth disease type 1A

    DEFF Research Database (Denmark)

    Hertz, Jens Michael; Børglum, A D; Brandt, C A

    1994-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) is an autosomal dominant peripheral neuropathy associated with a DNA duplication on chromosome 17p11.2-p12 in the majority of cases. Most of the sporadic cases are due to a de novo duplication. We have screened for this duplication in 11 Danish patients...

  4. Reklaamid nagu kino / Jean Marie Bouriscot ; interv.Valner Valme

    Index Scriptorium Estoniae

    Bouriscot, Jean Marie

    2001-01-01

    Sakala keskuses toimus reedel 6. korda reklaamiõgijate öö, kus näidati reklaamiklippe Jean Marie Bouriscotþ kogust. Kogu omanik polnud küll seekord ise kohal, kuid vastas siiski ajakirjaniku küsimustele oma huviala kohta

  5. Mary E. Hall: Dawn of the Professional School Librarian

    Science.gov (United States)

    Alto, Teresa

    2012-01-01

    A century ago, a woman named Mary E. Hall convinced school leaders of the need for the professional school librarian--a librarian who cultivated a love of reading, academic achievement, and independent learning skills. After graduating from New York City's Pratt Institute Library School in 1895, Hall developed her vision for the high school…

  6. From security to attachment : Mary Ainsworth's contribution to attachment theory

    NARCIS (Netherlands)

    Rosmalen, Lenette (Lenny) van

    2015-01-01

    Even though John Bowlby (1907-1990) is generally regarded as the founder of attachment theory, Mary Ainsworth’s (1913-1999) contribution is considerable and goes beyond the design of the Strange Situation Procedure and the introduction of maternal sensitivity as decisive for a secure attachment

  7. Reconnaissance Report for Hydropower Redevelopment at Sault Ste. Marie, Michigan.

    Science.gov (United States)

    1981-01-01

    Chairman Sugarman regarding the feasibility study on hydropower redevelopment at Sault Ste. Marie, Michigan The Commission would appreciate being...United States Government in a timely fashion. Sincerely, David A. LaRoche Secretary United States Section cc: Wingate Lloyd, Department of State F-II-8

  8. A Day in the Life of Mary Cassatt.

    Science.gov (United States)

    Stoppel, Julie

    2002-01-01

    Offers a way to present art history to classroom students where the art teacher pretends to be an artist. Focuses on a lesson where the teacher pretended to be Mary Cassatt. States that the students used pastels when drawing their artwork, in conjunction with the art history lesson. (CMK)

  9. The "Special" Way: Mary Paxton and Her Journalism Degree.

    Science.gov (United States)

    Flocke, Elizabeth Lynne

    The only woman in the first graduating class of the world's first school of journalism at the University of Missouri, Mary Paxton Keeley was offered a position as a special reporter for the "Kansas City Post" in 1910. As was typical for female journalists at the time, most of Paxton's assignments during her 15 months with the…

  10. Sigmoid Volvulus and Ileosigmoid Knotting at St. Mary's Hospital ...

    African Journals Online (AJOL)

    Sigmoid Volvulus and Ileosigmoid Knotting at St. Mary's Hospital Lacor in Gulu, Uganda. TR Okello, DM Ogwang, P Kisa, P Komagum. Abstract. Background: Sigmoid volvulus is a common cause of intestinal obstruction in developing countries where it affects relatively young people. Little is known about this condition in ...

  11. Marie and Irene Curie. The first female Nobel Prize winners; Marie en IreneCurie. De eerste vrouwelijke Nobelprijswinnaars

    Energy Technology Data Exchange (ETDEWEB)

    Noordenbos, G. [Joke Smit Instituut voor Vrouwenstudies, Universiteit Leiden, Leiden (Netherlands)

    2003-07-01

    Marie Curie was awarded the Nobel Prize in 1903 and in 1911. Also her daughter, Irene Joliot-Curie, received a Nobel Prize for science in 1935. In this book an overview is given of the academic world at that time: limited access to universities for women, the carriers of both women in physics and their pioneering research and discoveries, the refusal of Marie Curie by the French Academy of Sciences, the awarding of the Nobel Prize and the assignment of Irene Joliot-Curie as the first female minister in France, the impact of the two World Wars, their married and private lives and the constant smear campaign of the press against both women. The lives and works of both women are hold against the light of the present position of women in physical sciences. [Dutch] In 1903, precies honderd jaar geleden, ontving Marie Curie als eerste vrouw de Nobelprijs voor de Wetenschap, gevolgd door een tweede Nobelprijs in 1911. Ook haar dochter Irene Joliot-Curie kreeg de Nobelprijs voor de wetenschap in 1935. Marie and Irene Curie schetst een breed beeld van de academische wereld waarin beide vrouwen zich bewogen: de beperkte toegang van vrouwen tot de universiteit, hun carrisres in de natuurkunde en baanbrekende ontdekkingen, de afwijzing van Marie door de Franse Academie des Sciences, de toekenning van de Nobelprijs en de benoeming van Irene als eerste vrouwelijke minister in Frankrijk, de invloed van de twee Wereldoorlogen, hun huwelijks- en priveleven en de niet aflatende hetze van de pers tegen beiden. In de door mannen gedomineerde wereld van de natuurwetenschappen liep de uitzonderingspositie van beide vrouwen als rode draad door hun curieuze levens. Het leven en werk van de Curies wordt geactualiseerd door deze tegen het licht te houden van de huidige positie van vrouwen in de natuurwetenschappen. Het bereiken van de top van de wetenschap door vrouwen blijkt nog steeds uitzonderlijk.

  12. Experimental Physical Sciences Vistas: MaRIE (draft)

    Energy Technology Data Exchange (ETDEWEB)

    Shlachter, Jack [Los Alamos National Laboratory

    2010-09-08

    To achieve breakthrough scientific discoveries in the 21st century, a convergence and integration of world-leading experimental facilities and capabilities with theory, modeling, and simulation is necessary. In this issue of Experimental Physical Sciences Vistas, I am excited to present our plans for Los Alamos National Laboratory's future flagship experimental facility, MaRIE (Matter-Radiation Interactions in Extremes). MaRIE is a facility that will provide transformational understanding of matter in extreme conditions required to reduce or resolve key weapons performance uncertainties, develop the materials needed for advanced energy systems, and transform our ability to create materials by design. Our unique role in materials science starting with the Manhattan Project has positioned us well to develop a contemporary materials strategy pushing the frontiers of controlled functionality - the design and tailoring of a material for the unique demands of a specific application. Controlled functionality requires improvement in understanding of the structure and properties of materials in order to synthesize and process materials with unique characteristics. In the nuclear weapons program today, improving data and models to increase confidence in the stockpile can take years from concept to new knowledge. Our goal with MaRIE is to accelerate this process by enhancing predictive capability - the ability to compute a priori the observables of an experiment or test and pertinent confidence intervals using verified and validated simulation tools. It is a science-based approach that includes the use of advanced experimental tools, theoretical models, and multi-physics codes, simultaneously dealing with multiple aspects of physical operation of a system that are needed to develop an increasingly mature predictive capability. This same approach is needed to accelerate improvements to other systems such as nuclear reactors. MaRIE will be valuable to many national

  13. THE SEMANTICS OF BIRD DENOMINATIONS IN THE MARI LANGUAGE

    Directory of Open Access Journals (Sweden)

    Kristina Yuzieva

    2012-01-01

    Full Text Available This paper presents an analysis of the semantics of bird denominations in Mari: an attempt is made to define the factors, or features, motivating bird denominations. Analysis is based on a set of words of inner origin that are part of the corpus of bird names compiled by the author. The results show that the ornithonomy of the Mari language, created over centuries, constitutes a well-shaped system. It reflects a variety of features associated with the appearance, way of life of the birds, sounds they produce, etc. Many bird terms reflect features of appearance. It is interesting to note that the names of birds not seen for some reason may relate to the characteristics of the birds’ voices. In some cases, terms are based on a combination of features.In dialects, different names for same birds may occur, as observed in the sources.

  14. Mary Anne Chambers | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Mary Anne siège actuellement au conseil d'administration du GraceKennedy Group. Elle a également siégé au conseil des gouverneurs de l'Université de Guelph, au conseil d'administration de l'Université de Toronto, ainsi qu'aux conseils d'autres organisations sans but lucratif, comme Cuso International, le Centre de ...

  15. Rahvarõiva uus tulek / Mari Ird ; interv. Irene Roos

    Index Scriptorium Estoniae

    Ird, Mari

    2004-01-01

    Aastaid ajalooliselt õigeid Eesti rahvarõivaid loonud Mari Ird sellest, kuidas tänäpäeval rahvarõivaid valida, kanda ja hoida. Eesti rahvarõivaste huvitavatest tagamaadest, pidamise, käima-, seisu-, meeste, naiste ja laste rõivastest, pruudikroonist, jalanõudest. 14 ill.: Ruhnu naise rõivaste kolm varianti, Mulgi kihelkonna meeste, Karja kihelkonna naiste ja Pöide lesknaise riided

  16. Restaging Hysteria: Mary Wigman as Writer and Dancer

    OpenAIRE

    Laura A. McLary

    2003-01-01

    Mary Wigman was not only a leading proponent of the early twentieth-century Expressionist dance movement, but also a writer of poetry and short poetic prose. Despite her assertion that dance was beyond language, she wrote often about dance in an attempt to articulate the kinesthetic experience of dance through languages. This interdisciplinary study explores the intersection of dance and writing for Wigman, focusing on gender coding in writing and dance within the context of early twentieth-c...

  17. Revisiting Mary Daly: Towards a quadripartite theological and philosophical paradigm

    Directory of Open Access Journals (Sweden)

    Hannelie Wood

    2015-03-01

    Full Text Available I was a tenderfoot in feminist discourse when I started my research on patriarchy, feminism, and Mary Daly. In my thesis, one aspect I engaged was Daly’s battle with gender issues in Christian theology. From the beginning I was troubled by Mary Daly’s views on God, men, and women in her discourse on Christianity. Daly undoubtedly contributed to the discussion on gender issues in the Christian faith, but her focus on androcentrism and her interpretations of Scripture led her to abandon the Christian faith. Mary Daly has written extensively on patriarchy as it is found in religion – particularly in the Christian faith – and how it filters through society. In her critique of patriarchy she set her course to dismantle the facade of a patriarchal and misogynistic God as the root of patriarchy. Daly did not see any positive qualities of the Christian faith and completely rejected other interpretations of a God whose person embraces both male and female qualities. Against this background I will evaluate Daly’s post-Christian feminist theological and philosophical paradigm. I propose that Daly has a quadripartite theological and philosophical paradigm wherein there are four main players. The ‘Who is who’ in Daly’s quadripartite patriarchal theological and philosophical paradigm are the patriarchal male, the patriarchal female, the patriarchal God and the biophilic woman.

  18. The Pasteurization of Marie Curie: A (meta)biographical experiment.

    Science.gov (United States)

    Wirtén, Eva Hemmungs

    2015-08-01

    Biographies of scientists occupy a liminal space, highly popular with general readers but questioned in academia. Nonetheless, in recent years, historians of science have not only embraced the genre with more enthusiasm and less guilt, they have also turned to the metabiography in order to renew the study and story of scientists' roles. This essay focuses on Marie Curie, the world's most famous female scientist, in order to unpack some of the theoretical and methodological claims of the science biography, and especially to address the sexing mechanisms at play in the construction of the biographical subject. Pierre Curie (1923), Marie's biography of her husband Pierre, paid tribute to her dead husband and collaborator, but also allowed Curie a legitimate outlet to construct her own persona and legacy. Categories such as personhood, person, and persona are not only central to the biography genre but also are essential to the sense of self and self-fashioning of scientists. Looking at how Marie Curie negotiated these categories in Pierre Curie not only gives new insight into Curie's self-fashioning strategies but may also shed some light on the more general analytical lacunae of the science biography.

  19. Church of St. Mary of the Mongols in Istanbul

    Directory of Open Access Journals (Sweden)

    Ilyas Kemaloglu (Kamalov

    2014-12-01

    Full Text Available Istanbul, throughout its history, has accommodated many states and civilizations. Therefore, the city besides having different names, also has monuments and places of worship belonging to various cultures and faiths. Due to this characteristics of the city there are Catholic, Orthodox, Armenian and Protestant churches along with the mosques and synagogues. Although the Mongols of Genghis Khan has never ruled Istanbul, one of the churches in the city is called Church of St. Mary of the Mongols. Called Despina khatun by the Mongols, St. Mary, whose names is given to the church, is the daughter of a Byzantine emperor Michael VIII. The Byzantine emperors paid importance to establish kinship ties both with Golden Horde and Ilkhanid states. Through the princes they aimed at preserving the balance and wanted to please the khans. Pursuing this policy, Mary had married to an Ilkhanid khan, Abaqa. After his death she returned to Istanbul and devoted herself to religion. Surviving until present, the church that was built and named by herself in Istanbul attracts attention both with its story of foundation and its name.

  20. 78 FR 9940 - Naugatuck Valley Surgical Center, Department of Saint Mary's Hospital, Waterbury, CT: Notice of...

    Science.gov (United States)

    2013-02-12

    ..., Waterbury, CT: Notice of Affirmative Determination, Regarding Application for Reconsideration By application... Saint Mary's Hospital, Waterbury, Connecticut ] (subject firm). The determination was issued on December...

  1. An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients

    Science.gov (United States)

    2017-06-09

    Charcot Marie Tooth Disease (CMT); Hereditary Sensory and Motor Neuropathy; Nerve Compression Syndromes; Tooth Diseases; Congenital Abnormalities; Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System

  2. Charcot-marie-tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2011-07-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  3. Charcot-Marie-Tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2012-02-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  4. The ascent of Mary Somerville in 19th century society

    CERN Document Server

    Strickland, Elisabetta

    2016-01-01

    This biography traces the life and work of Mary Fairfax Somerville, whose extraordinary mathematical talent only came to light through fortuitous circumstances. Barely taught to read and write as a child, all the science she learned and mastered was self taught. In this delightful narrative the author takes up the challenge of discovering how Somerville came to be one of the most outstanding British women scientists and, furthermore, a popular writer. Particular attention is paid to the gender aspects of Somerville's success in what was, to put it mildly, a predominantly male domain.

  5. Mary Wakefield: Health Resources and Services Administrator. Interview.

    Science.gov (United States)

    Wakefield, Mary

    2014-06-01

    Dr. Mary Wakefield is the administrator of the Health Resources and Services Administration. She came from the University of North Dakota, where she directed the Center for Rural Health. She has served as director of the Center for Health Policy, Research and Ethics at George Mason University and has worked with the World Health Organization's Global Programme on AIDS in Geneva, Switzerland. She is a fellow in the American Academy of Nursing and was elected to the Institute of Medicine of the National Academies. A native of North Dakota, Wakefield holds a doctoral degree in nursing from the University of Texas.

  6. Uus kuum Eesti disain / Silvia Pärmann, Maris Takk

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2015-01-01

    Karl Tauli disainitud taburet "Ämblu", Aap Piho puidust ümmargune laud, Marit Ilisoni tekkmantlid kollektsioonist "Longing for Sleep/Magada tahaks", Narma vaibakollektsioon "OPEN 2015/16" (disainerid Monika Järg, Kaidi Ploomipuu), Annike Laigo vaibakollektsioon "XX", Kairi Katmanni vaip "Storytellers", Valhalla Factory kollektsiooni "Daydreamers" ripptool, Raili Keivi betoonist ja portselanist nõudekollektsioon, Tarmo Luisu valgusti "Kassett", Stella Soomlaisi käekotid, Karin Kallase ja Erik Pasti (Stuudio Nahk) disainitud jalatsid, käekotid ja ehted, Kuula + Jylhä jalatsikollektsioon, Mokoko (disainer Mari Maripuu) nahast aksessuaarid

  7. Aspects of emic and etic measurement: lessons from Mary Poppins.

    Science.gov (United States)

    Lee, Christopher J

    2002-01-01

    This article describes emic and etic approaches to measurement in terms of a process of associating indicators and constructs. In this process, it is important to establish evidence of an adequate range of indicators and a relevant association of indicators and constructs and to recognize that such evidence places bounds on the interpretation of measurement outcomes. A passage from one of P. L. Travers's Mary Poppins stories provides a counterpoint for this article's discussion of these key aspects of emic and etic methods of measuring human individuality.

  8. Hairy Mary: Natal Government Railways 2-8-2 (Tanic Tender ...

    African Journals Online (AJOL)

    was covered with thick Hemp rope. The rope was draped over the entire locomotive from front to back and because the rope was. "hairy" she was given the name of "Hairy Mary" by the soldiers. She carried the number of 48. This engine was scrapped in 1905. Photograph of "Hairy Mary". WOII JA Hattingh, Diploma (Printers) ...

  9. Using the "Mary Tyler Moore Show" as a Feminist Teaching Tool

    Science.gov (United States)

    Jule, Allyson

    2010-01-01

    This paper explores the use of "The Mary Tyler Moore Show" as a teaching tool used with a group of final-year undergraduate students who gathered together last academic year (2007-8) to explore Women in Leadership, as part of a Communications course. The research focus was: How can the use of "The Mary Tyler Moore Show" (a…

  10. Mari Kurismaa : "Kodu kujundamine vajab isiklikku põhjust" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Mari Kurismaa (sünd. 1956) värvide valikust, kodu kujundamisest, praegusest arhitektuurist ja sisearhitektuurist. Mari Kurismaast, autasud (2002. a. Mies van der Rohe preemia EALi-poolne nominent Jaak Huimerinna ja Indrek Saareperaga Järve Selveri projekti töögrupis). Ill.: neli värv. portreed M. Kurismaast

  11. "Does Broca's Area Exist?:" Christofredo Jakob's 1906 Response to Pierre Marie's Holistic Stance

    Science.gov (United States)

    Tsapkini, Kyrana; Vivas, Ana B.; Triarhou, Lazaros C.

    2008-01-01

    In 1906, Pierre Marie triggered a heated controversy and an exchange of articles with Jules Dejerine over the localization of language functions in the human brain. The debate spread internationally. One of the timeliest responses, that appeared in print 1 month after Marie's paper, came from Christofredo Jakob, a Bavarian-born neuropathologist…

  12. Auto möirgab, ratas laulab / Mari Jüssi ; interv. Ylle Rajasaar

    Index Scriptorium Estoniae

    Jüssi, Mari, 1971-

    2008-01-01

    Uue Maailma Seltsi liige Mari Jüssi Eesti Rohelisest Liikumisest ja Uue Maailma Seltsist ka Tallinna linnaplaneerimisest, ühistranspordist, teede planeerimisest, valglinnastumisest, rattateedest, raudtee võimaluste vähesest kasutamisest. Mari Jüssi teemadeks on säästev transpordipoliitika ja autovaba linnaplaneerimine

  13. Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy.

    NARCIS (Netherlands)

    Claeys, K.G.; Zuchner, S.; Kennerson, M.; Berciano, J.; Garcia, A.; Verhoeven, K.; Storey, E.; Merory, J.R.; Bienfait, H.M.; Lammens, M.M.Y.; Nelis, E.; Baets, J.; Vriendt, E. De; Berneman, Z.N.; Veuster, I. De; Vance, J.M.; Nicholson, G.; Timmerman, V.; Jonghe, P. de

    2009-01-01

    Dominant intermediate Charcot-Marie-Tooth neuropathy type B is caused by mutations in dynamin 2. We studied the clinical, haematological, electrophysiological and sural nerve biopsy findings in 34 patients belonging to six unrelated dominant intermediate Charcot-Marie-Tooth neuropathy type B

  14. Charcot-Marie-tooth disease presenting in a young Nigerian male: A ...

    African Journals Online (AJOL)

    Charcot-Marie-tooth disease presenting in a young Nigerian male: A case report. ... International Journal of Medicine and Health Development ... of a 31-year-old man presenting to the medical outpatient clinic of the University of Nigeria Teawching Hospital Enugu with features of Charcot-Marie-Tooth disease is presented.

  15. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology

    CERN Multimedia

    Patrice Loiez

    2002-01-01

    Photo 0210006_07a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_14a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_22: Dr. David Plane (CERN) introducing Dr. Theodore Papazoglou from the European Commission. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellowships in the 6th Framework Programme". Photo 0210006_28a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN and Dept. of Physics, University of Milan. Addressing the Marie-Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellows Association". Photo 0210006_29a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN a...

  16. Modell Kaja Wunder osaleb Eestis moesõul / Valdo Jahilo

    Index Scriptorium Estoniae

    Jahilo, Valdo, 1972-

    2001-01-01

    Tallinna Moemaja rõivadisaineri Kairi Vildersoni kollektsiooni demonstratsioon Kunstihoones, kus modellinna osaleb Kaja Vunder (modellinimi Kaja Wunder) ; Kaja Vunderi elust ja tegevusest moe ja muusika vallas

  17. Miks IBM müüb kroonijuveeli? / Valdo Randpere

    Index Scriptorium Estoniae

    Randpere, Valdo, 1958-

    2004-01-01

    Kuna konkurents on väga tihe, siis IBM loobub väikese marginaaliga personaalarvutite ärist ning keskendub serveritele ja keerukatele ärilahendustele. Lisa: IBM müüb personaalarvutite divisjoni hiinlastele

  18. Marie Curie nurses: enabling patients with cancer to die at home.

    Science.gov (United States)

    Higginson, Irene J; Wilkinson, Susie

    2002-05-01

    Marie Curie Cancer Care established its nursing service in 1958; however, the service has had little formal evaluation. This study aimed to describe and evaluate the care provided by Marie Curie nurse, and in particular to determine whether patients in their care remained and died at home. Two existing data sets were used: data on all patients referred to the Marie Curie Nursing Services in 147 areas of England, Wales, Scotland and Northern Ireland for 26 months, and data on cancer death registrations in England. A request for a Marie Curie nurse was made for 26,632 patients, 97% of whom had cancer and 11% of whom lived alone. The amount of care provided varied enormously (Marie Curie nurses facilitated home death for many patients. Services need to ensure that mechanisms are in place to achieve data collection. Rigorous prospective evaluation is needed in the future.

  19. Angles of Refraction: The Letters of Mary Delany

    Directory of Open Access Journals (Sweden)

    Eleonora Chiavetta

    2014-04-01

    Full Text Available Mary Delany (1700-1788 is particularly famous for her paper-cuttings or ‘mosaicks’ based on botanical subjects. A very lively woman of fashion, she was close to Queen Charlotte and one of the Bluestocking Ladies. She left a vivid portrait of life and society in eighteenth century England and Ireland in the six volumes of her Autobiography and Letters, edited in 1861 by her descendant Lady Llanover. Her autobiography is made up of 18 letters sent to her most intimate friend, Margaret Cavendish, Duchess of Portland. The first letter is dated 1740, but in this, as in the following ones, Mrs. Delany narrates her past life to her friend, starting from the early years of her life, describing her unhappy marriage, financial difficulties as a widow, and family relationships. Along with these ‘autobiographical’ letters, other letters written by her to her sister Ann are introduced, which date to the periods of life Mrs. Delany is dealing with. The aim of this paper is to focus on the textual, linguistic and content differences between the two letter types, and analyse how the identity of Mary Delany is differently constructed and perceived in the explicit autobiographical letters addressed to the Duchess of Portland, and the ones written to her sister. 

  20. Marie Nimier, au cœur du silence

    Directory of Open Access Journals (Sweden)

    Joëlle Papillon

    2012-01-01

    Full Text Available Dans La Reine du silence, Marie Nimier se confronte à la figure de son père, l’écrivain Roger Nimier, mort lorsqu’elle avait cinq ans. Elle y montre le poids qui pèse sur l’enfant d’écrivain, mais aussi celui de l’héritage du secret familial et de l’injonction au silence. La difficulté de l’élaboration de son récit de filiation se révèle dans les constants recommencements et reformulations, qui constituent la marque de la tension angoissante entre l’obligation de dire et celle de taire. In La Reine du silence, Marie Nimier confronts her father’s memory – the writer Roger Nimier, who died when she was five years old. The novel describes the burden of being a writer’s child, along with that of inheriting family secrets and submitting to a code of silence. The difficulty of recounting her relationship with her late father is evidenced by the narrator’s numerous “false starts” and her constant rewritings. The hesitant nature of the narration captures an anguish born of two irreconcilable obligations : the need to put things into words and the pressure to remain silent.

  1. Taking Stock: Marie Nimier’s Textual Cabinet of Curiosities

    Directory of Open Access Journals (Sweden)

    Adrienne Angelo

    2014-01-01

    Full Text Available In many life-writing projects, the seemingly innocuous description of heteroclite objects and how those objects are stored and recalled in fact plays an important role in demonstrating their importance to the process of memory work. At once the lingering traces of one’s past and also an aggregation of stories evoked by an examination of them, these curios focus attention on the relationship between the individual and the storage of memories. This article will focus on certain collectibles, collections and collectors that appear throughout the fictional, autobiographical and autofictional world that Marie Nimier has scripted to date. This textual cabinet of curiosities and the act of collecting more generally serve as a trope to connect memory with materiality, despite the numerous narrative voices that Nimier assumes—voices that move from a first-person “Marie Nimier” to an unnamed, although clearly identifiable first-person and even float between genders. Despite this nominal and narrational fluidity, objects function to guarantee recognition, both for the reader, and, especially, for the author herself. What is at stake in this intertextual assemblage of objects is not only the roles that they play in allowing the narrator to revisit past traumas and loss, but also in connecting the author’s presence to other, more fictionalized voices that above all signify the primacy of life-writing in her corpus.

  2. Mary Dorcey: The Poet’s Gaze and Scalpel

    Directory of Open Access Journals (Sweden)

    Maria Micaela Coppola

    2015-07-01

    Full Text Available Precision, vividness and colour characterise Mary Dorcey’s representations of individual and yet universal human experiences, such as love, loss, or grief. These are used like a surgeon’s scalpel: to frame, look inside, and closely observe sections of the individual’s body, and life. As we can see from the selection of poetic and prose texts presented here (alongside their translations into Italian, Dorcey cuts the skin of common definitions of private places and feelings (home, love, and grief. She looks at them from uncommon perspectives, bears witness to them, and gains insight from them. These and other issues are discussed in the interview, which is a revised version of a conversation that took place in Bologna (Italy in November 2014.

  3. Marie Curie: the Curie Institute in Senegal to Nuclear Physics

    Science.gov (United States)

    Gueye, Paul

    Sub-Saharan Africa is not a place where one will look first when radioactivity or nuclear physics is mentioned. Conducting forefront research at the international stage at US national facilities such as the Thomas Jefferson National Accelerator Facility in Virginia or the National Superconducting Cyclotron Facility/Facility for Rare Isotope Beams in Michigan does not point to Historically Black Colleges either. The two are actually intrinsically connected as my personal journey from my early exposure to radiation at the Curie Institute at the LeDantec Hospital in Senegal lead me to Hampton University. The former, through one of my uncles, catapulted me into a nuclear physics PhD while the latter houses the only nuclear physics program at an HBCU to date that has established itself as one of the premier programs in the nation. This talk will review the impact of Marie Curie in my life as a nuclear physicist.

  4. Hand weakness in Charcot-Marie-Tooth disease 1X.

    LENUS (Irish Health Repository)

    Arthur-Farraj, P J

    2012-07-01

    There have been suggestions from previous studies that patients with Charcot-Marie-Tooth disease (CMT) have weaker dominant hand muscles. Since all studies to date have included a heterogeneous group of CMT patients we decided to analyse hand strength in 43 patients with CMT1X. We recorded handedness and the MRC scores for the first dorsal interosseous and abductor pollicis brevis muscles, median and ulnar nerve compound motor action potentials and conduction velocities in dominant and non-dominant hands. Twenty-two CMT1X patients (51%) had a weaker dominant hand; none had a stronger dominant hand. Mean MRC scores were significantly higher for first dorsal interosseous and abductor pollicis brevis in non-dominant hands compared to dominant hands. Median nerve compound motor action potentials were significantly reduced in dominant compared to non-dominant hands. We conclude that the dominant hand is weaker than the non-dominant hand in patients with CMT1X.

  5. Migration and Metamorphosis in Marie Ndiaye's Trois Femmes Puissantes

    Directory of Open Access Journals (Sweden)

    Deborah B. Gaensbauer

    2014-01-01

    Full Text Available In her 2009 Goncourt-Prize-winning novel, Trois femmes puissantes ( Three Strong Women, Marie Ndiaye experiments with a polyphonic, semi-fantastical rendering of identity-threatening displacements experienced by three women from different socio-geographic backgrounds. In a brief "Counterpoint" at the end of each of the novel's three sections--a narrative take on the musical technique employed by Ndiaye to introduce new focalizations and unexpected turns of events that complicate interpretations of the characters' behavior--each of the women is perceived as metamorphosed into a bird or a birdlike persona. This essay examines the innovative embedding of the shape-shifts in Trois femmes puissantes in both harrowing socio-political realities and the ambiguities of the fantastic and superstition to convey the dehumanizing, unequal power relations governing contemporary women's migration struggles.

  6. NARRATIVES OF INTERNAL EXILE IN MARY LAVIN'S SHORT STORIES

    Directory of Open Access Journals (Sweden)

    Marie Arndt

    2002-12-01

    Full Text Available Paul Tabori's definition of exile and Michael Seidel's discussion of the "exilic mind" are the points of departure for this study of short stories by Mary Lavin. The stories deal with internal exile, meaning marginalisation within the local community or native country, due to that individual will is incompatible with pressure to conform to unwritten rules of society. The narratives of the stories strongly suggest that these characters are subversive according to the dominant ethos of the restrictive Catholic lreland that Lavin writes about. Women who do not fulfil their enforced social role of wife or mother and the restrictions of young widows feature in several stories. But some stories show that internal exile also affects men, Ieaving thern in a social vacuum. The novella "The Becker Wives" will be discussed at Iength as an explicit and striking narrative of internal exile on an individual and a social level.

  7. Progress in treatment of Charcot-Marie-Tooth disease

    Directory of Open Access Journals (Sweden)

    Ru-xu ZHANG

    2017-09-01

    Full Text Available Charcot-Marie-Tooth disease (CMT comprises a group of monogenic inherited peripheral neuropathies with highly clinical and genetic heterogeneity, more than 80 causative genes have been cloned at present. Usually starts in childhood or juvinile period, the main clinical manifestations include progressive length.dependent muscle weakness and atrophy, sensory loss, areflexia and pes cavus. Although there is no specific treatment to reverse the natural disease course of CMT, symptomatic treatments such as rehabilitation, orthopedic surgery and medication can improve the overall fitness and life quality of CMT patients. Targeted treatments based on pathogenesis study is expected to provide precise therapy for CMT patients. This paper aims to make a review of the clinical application of symptomatic treatments and progress of target therapy researches in different CMT subtypes. DOI: 10.3969/j.issn.1672-6731.2017.08.003

  8. The lives of Mary Foote: painter and Jungian.

    Science.gov (United States)

    Trousdell, Richard

    2016-11-01

    Mary Foote (1872-1968) was a successful early twentieth century American artist who suddenly closed her New York studio in 1926 to go to Zurich to study with Jung. There she joined his 'Interpretation of Visions' seminars (1930-1934), which she recorded and edited. This work won Jung's praise and his friendship, but all too often Foote was seen merely as a secretary or background figure. Deirdre Bair's biography of Jung suggested that Foote's life and work deserved fuller study, if only to rebalance our view of Jung's early women followers. This paper takes up that work to ask how Foote's early life and career led to her important work in preserving and describing Jung's earliest attempts to apply his theories to clinical practice. © 2016, The Society of Analytical Psychology.

  9. Mari Paz Corominas. "Sola en lugares de agua"

    OpenAIRE

    Asins, Consuelo

    1999-01-01

    Una canción suena en los tocadiscos de medio mundo; "sittin'on" (1). La voz que se escucha murió el año pasado. Otis Reding perdió la vida en un accidente de aviación sin saber que la última canción que grababa se convertiría en un su-per-ventas en 1968, y en un clásico que se alargaría hasta acariciar los oídos del 2000. 1968, México, Olimpiadas y Mari paz Corominas, la primera mujer española que consiguió llegar a una final olímpica en natación. Las hadas o las brujas quisieron que el 68 fu...

  10. MaRIE: an experimental facility concept revolutionizing materials in extremes

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris W [Los Alamos National Laboratory

    2011-01-07

    The Matter-Radiation Interactions in Extremes (MaRIE) project intends to create an experimental facility that will revolutionize the control of materials in extremes. That control extends to extreme regimes where solid material has failed and begins to flow - the regimes of fluid dynamics and turbulent mixing. This presentation introduces the MaRIE facility concept, demonstrates examples of the science case that determine its functional requirements, and kicks-off the discussion of the decadal scientific challenges of mixing in extremes, including those MaRIE might address.

  11. Aspectos históricos da visita de Marie Sklodowska Curie a Belo Horizonte

    Directory of Open Access Journals (Sweden)

    Cássius Klay Nascimento

    2011-01-01

    Full Text Available In the year 2011 it is celebrated the Marie Sklodowska Curie Nobel Prize centenary and the International Year of Chemistry. However, it is not generally known that Marie Sklodowska Curie, one of the greatest scientists of all time, visited Belo Horizonte, state of Minas Gerais, Brazil. She arrived by train at Belo Horizonte city on 16 August 1926, coming from Rio de Janeiro and accompanied by her daughter Irène Joliot-Curie. The scientists visited the Institute of Radium of Belo Horizonte. The approach in this work emphasizes the presence of Marie Sklodowska Curie in Belo Horizonte, exploring the admiration and respect that people had for her.

  12. Mouse model for Charcot-Marie-Tooth as a tool to better understand the disease

    OpenAIRE

    Barneo Muñoz, Manuela

    2016-01-01

    Introducción La enfermedad de Charcot-Marie-Tooth (CMT) es uno de los trastornos neurológicos hereditarios más comunes que afecta a 17-40 de cada 100.000 personas según poblaciones; concretamente esta cifra se sitúa en 28 personas de cada 100.000 en España. La enfermedad recibe el nombre de los tres médicos que la identificaron por primera vez en 1886; Jean-Marie Charcot y Pierre Marie en París, Francia y Howard Henry Tooth en Cambridge, Inglaterra. La enfermedad de CMT, también conocida c...

  13. Mary Reynolds: a post-traumatic reinterpretation of a classic case of multiple personality disorder.

    Science.gov (United States)

    Goodwin, J

    1987-01-01

    In 1811 Mary Reynolds, a somber Pennsylvania spinster, awoke from a prolonged sleep as a new personality. Family memoirs describing her 18 years of shifts between two personalities shaped nineteenth century thinking about multiple personality disorder. As in other early case histories, no mention was made of childhood trauma, a factor found in 97% of contemporary cases. This discussion reviews genealogical and historical documents which suggest that Mary Reynolds did experience early trauma as a victim of religious persecution, which finally forced her family to leave Birmingham, England, when Mary was eight. Review of her illness indicates it may have functioned to eradicate memories of traumatic early experiences.

  14. Tarvo Hanno Varres, Mari-Leen Kiipli / Merilin Talumaa, Hanno Soans, Tatjana Kozlova-Johannes

    Index Scriptorium Estoniae

    Talumaa, Merilin, 1986-

    2015-01-01

    Vaatluse alla on võetud Tarvo Hanno Varrese heli- ja videoinstallatsioon "Lindistav põrand" (2015) ja heli- ja videoteos "Betweenland" (2014) ning Mari-Leen Kiipli fotoseeria "The school of dreams" (2012-2015)

  15. The Mesoscale Science of the Matter-Radiation Interactions in Extremes (MaRIE) project

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Donald Raymond [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-17

    The National Nuclear Security Administration (NNSA) requires the ability to understand and test how material structures, defects, and interfaces determine performance in extreme environments such as in nuclear weapons. To do this, MaRIE will be an x-ray source that is laser-like and brilliant with very fl exible and fast pulses to see at weapons-relevant time scales, and with high enough energy to study critical materials. The Department of Energy (DOE) has determined there is a mission need for MaRIE to deliver this capability. MaRIE can use some of the existing infrastructure of the Los Alamos Neutron Science Center (LANSCE) and its accelerator capability. MaRIE will be built as a strategic partnership of DOE national laboratories and university collaborators.

  16. Romance, recognition and revenge in Marie Clements's The Unnatural and Accidental Women

    National Research Council Canada - National Science Library

    Bamford, Karen

    2010-01-01

    This essay considers the relationship of Marie Clements's The Unnatural and Accidental Women to European traditions of drama and folk narrative, and especially its relation to the genres of revenge tragedy and romance...

  17. Eesti animafilm külvab uusi seemneid / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis

    2009-01-01

    PÖFFi alafestivalil Animated Dreams linastunud neljast uuest filmist: Olga ja Priit Pärna "Tuukrid vihmas", Kaspar Jancise "Krokodill", Martinus Daane Klemeti "Õhus" ja Girlin Bassovskaja (Jelena Girlin, Mari-Liis Bassovskaja) "Oranus"

  18. Igal mõisal on oma lugu / Mari-Ann Remmel

    Index Scriptorium Estoniae

    Remmel, Mari-Ann

    2008-01-01

    Kirjastuselt "Tänapäev" ilmus raamat "Mõisalegendid. Harjumaa", koostaja Mari-Ann Remmel, kujundaja Angelika Schneider. Kogumik sisaldab ka ajaloolist ning genealoogilist teavet mõisahoonete ning -omanike kohta

  19. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  20. Ämaris asuvad hävitajad lendavad täies relvis

    Index Scriptorium Estoniae

    2016-01-01

    Ämari õhubaasis asuvad Saksa õhujõudude hävitajad Eurofighter Typhoon on Ukraina konflikti tõttu varustatud täieliku lahingrelvastusega, hävitajatel on lühi-ja keskmaaraketid, kirjutab Spiegel

  1. Precipitation and stream water stable isotope data from the Marys River, Oregon in water year 2015.

    Data.gov (United States)

    U.S. Environmental Protection Agency — Water stable isotope data collected from a range of streams throughout the Marys River basin in water year 2015, and precipitation data collected within the basin at...

  2. Saukas ja Karusoo tõid Marie Underi elu teatrilavale / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    20. nov. Kumu auditooriumis esietendunud Ühenduse R.A.A.A.M teatriprojekt "Under" poetess Marie Underist. Lavastajad Merle Karusoo ja Raimo Pass, kunstnik Jaagup Roomet, helilooja Urmas Lattikas, peaosas Katrin Saukas

  3. Mary Loli Martínez-Aldama - Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Aldama. Articles written in Journal of Astrophysics and Astronomy. Volume 36 Issue 4 December 2015 pp 457-465 Review. Observations of the Ca I I IR Triplet in High Luminosity Quasars: Exploring the Sample · Mary Loli ...

  4. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2003-01-01

    Concordia Ülikooli rektor Mart Susi esitas kohtule avalduse, milles taotleb ülikooli pidanud Concordia Varahalduse OÜ pankroti väljakuulutamist. Vt. samas: Mari-Ann Susi õigustas ülikooli raha kasutamist

  5. Mary as Mother in the Flores de Mayo in Poblacion, Oslob

    Directory of Open Access Journals (Sweden)

    Patricia Marion Y. Lopez

    2016-06-01

    Full Text Available The paper reflects on the meanings of the Flores de Mayo ritual as performed in a town on the southeastern coast of Cebu through the examination of Mary as a “semantically open” symbol. The essay illustrates how ideas about Mary are constructed through the discourse of the Church and are in turn, reinforced through a Church-instituted and regulated ritual. An analysis of selected elements of the ritual however, reveals that the symbol of Mary has the potential to hold “other” kinds of meanings that slip in between “official” and “unofficial” discourses, highlighting how Mary continues to be a negotiated field between church authorities and the popular faithful.

  6. On the Turn of Two Millennia (60 Years of the Mari Archaeological Expedition

    Directory of Open Access Journals (Sweden)

    Nikitin Valeriy V.,

    2017-03-01

    Full Text Available The article is dedicated to the 60th Anniversary of the Mari Archaeological Expedition and summarizes the two decades of its studies (1996-2016 into the early cultures of the Mari region, starting from the era of the original settlement (Mesolithic, through the Neolithic-Eneolithic, Bronze Age, Early Iron Age and up to the Middle Ages. The expedition studied stations and settlements of primitive cultures, as well as unfortified and fortified settlements and necropolises. Special studies focused on formation and development of the early Mari culture, as well as the material and spiritual culture of the medieval Mari. The expedition continues its survey exploration in order to identify new archaeological sites. During the reported period, twelve monographs were published and three monographs prepared based on the expedition’s materials.

  7. Ooperi valem : Mari Vihmandi "Armastuse valem" / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  8. Kirjanike aed Nõmme-Rahumäel / Elle-Mari Talivee

    Index Scriptorium Estoniae

    Talivee, Elle-Mari, 1974-

    2016-01-01

    Artur Adsoni ja Marie Underi Rahumäele Vabaduse puiestee ja Veere tänava nurgale ehitatud eramust (arhitekt Edgar Johan Kuusik) ning krundile rajatud iluaiast. Aastast 1944 elasid seal Friedebert ja Elo Tuglas

  9. Twice-Told Traumas: whatever Happened to Mary Rogers or Poe's Reveng on Life

    OpenAIRE

    Miquel-Baldellou, Marta

    2011-01-01

    In 2006, the American scholar and writer Daniel Stashower published The Beautiful Cigar Girl: Mary Rogers, Edgar Allan Poe and the Invention of Murder. In this post-modem work, which can be described as a mixture of historical and detective narration, Stashower intercalates the investigation of Mary Rogers' murder and Edgar Allan Poe's simultaneous fictionalisation of the actual events in his tale 'The Mystery of Mane Rogêt". Even if Poe boasted he had managed to solve the case, updated infor...

  10. The seminal role played by Pierre Marie in Neurology and Internal Medicine

    Directory of Open Access Journals (Sweden)

    Gustavo M Almeida

    2015-10-01

    Full Text Available The authors review the most important contributions of Pierre Marie to the elucidation and description of several neurological diseases, such as Charcot-Marie-Tooth’s disease and hereditary cerebellar ataxia, as well as his contributions to Internal Medicine, including his pioneering studies on acromegaly, ankylosing spondylitis, and hypertrophic pulmonary osteoarthropathy. His works led to incontestable advances in the medical sciences that transcended his time.

  11. Hand weakness in Charcot-Marie-Tooth disease 1X.

    Science.gov (United States)

    Arthur-Farraj, P J; Murphy, S M; Laura, M; Lunn, M P; Manji, H; Blake, J; Ramdharry, G; Fox, Z; Reilly, M M

    2012-07-01

    There have been suggestions from previous studies that patients with Charcot-Marie-Tooth disease (CMT) have weaker dominant hand muscles. Since all studies to date have included a heterogeneous group of CMT patients we decided to analyse hand strength in 43 patients with CMT1X. We recorded handedness and the MRC scores for the first dorsal interosseous and abductor pollicis brevis muscles, median and ulnar nerve compound motor action potentials and conduction velocities in dominant and non-dominant hands. Twenty-two CMT1X patients (51%) had a weaker dominant hand; none had a stronger dominant hand. Mean MRC scores were significantly higher for first dorsal interosseous and abductor pollicis brevis in non-dominant hands compared to dominant hands. Median nerve compound motor action potentials were significantly reduced in dominant compared to non-dominant hands. We conclude that the dominant hand is weaker than the non-dominant hand in patients with CMT1X. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Princess Marie Bonaparte, Edgar Allan Poe, and psychobiography.

    Science.gov (United States)

    Warner, S L

    1991-01-01

    Princess Marie Bonaparte was a colorful yet mysterious member of Freud's inner circle of psychoanalysis. In analysis with Freud beginning in 1925 (she was then 45 years old), she became a lay analyst and writer of many papers and books. Her most ambitious task was a 700-page psychobiography of Edgar Allan Poe that was first published in French in 1933. She was fascinated by Poe's gothic stories--with the return to life of dead persons and the eerie, unexpected turns of events. Her fascination with Poe can be traced to the similarity of their early traumatic life experiences. Bonaparte had lost her mother a month after her birth. Poe's father deserted the family when Edgar was two years old, and his mother died of tuberculosis when he was three. Poe's stories helped him to accommodate to these early traumatic losses. Bonaparte vicariously shared in Poe's loss and the fantasies of the return of the deceased parent in his stories. She was sensitive and empathetic to Poe's inner world because her inner world was similar. The result of this psychological fit between Poe and Bonaparte was her psychobiography, The Life and Works of Edgar Allan Poe. It was a milestone in psychobiography but limited in its psychological scope by its strong emphasis on early childhood trauma. Nevertheless it proved Bonaparte a bona fide creative psychoanalyst and not a dilettante propped up by her friendship with Freud.

  13. The contribution of women to radiobiology: Marie Curie and beyond.

    Science.gov (United States)

    Gasinska, Anna

    2016-01-01

    Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and worked in France, led to the development of nuclear energy and the treatment of cancer. She was the laureate of two Nobel Prizes, the first woman in Europe who obtained the degree of Doctor of Science and opened the way for women to enter fields which had been previously reserved for men only. As a result of her determination and her love of freedom, she has become an icon for many female scientists active in radiation sciences. They are successors of Maria Curie and without the results of their work, improvement in radiation oncology will not be possible. Many of them shared some elements of Maria Curie's biography, like high ethical and moral standards, passionate dedication to work, strong family values, and scientific collaboration with their husbands. The significance of Tikvah Alper, Alma Howard, Shirley Hornsey, Juliana Denekamp, Helen Evans, Eleanor Blakely, Elizabeth L. Travis, Fiona Stewart, Andree Dutreix, Catharine West, Peggy Olive, Ingela Turesson, Penny Jeggo, Irena Szumiel, Eleonor Blakely, Sara Rockwell and Carmel Mothersill contribution to radiation oncology is presented. All the above mentioned ladies made significant contribution to the development of radiotherapy (RT) and more efficient cancer treatment. Due to their studies, new schedules of RT and new types of ionizing radiation have been applied, lowering the incidence of normal tissue toxicity. Their achievements herald a future of personalized medicine.

  14. A family study of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Brooks, A P; Emery, A E

    1982-04-01

    Forty-seven cases of Charcot-Marie-Tooth peripheral neuropathy were seen in 18 families within a defined area, with a disease prevalence of 1 in 16 400. Maximum motor nerve conduction velocity (MNCV) measurement divided off two types of neuropathy (MNCV less than 30 ms-1 and greater than 40 ms-1), but did not distinguish clinically affected from normal in families whose probands had median nerve MNCV greater than 40 ms-1. In the neuronal type of neuropathy ((MNCV greater than 40 ms-1) two genotypes were seen, autosomal dominant (ADN) and autosomal recessive (ARN). Most cases with the demyelinating type (MNCV less than 30 ms-1) had an autosomal dominant genotype (ADD) but one family had possible X linked recessive inheritance (XRD). In one autosomal dominant family a father and son had different electrophysiological types of neuropathy. Peroneal muscle weakness was progressive with age in the ADD genotype and certain patterns of phenotypic features were associated with the major genotypes. Age of onset was not found to be reliable in distinguishing genotypes. Care is needed when counselling isolated male cases because of asymptomatic affected females in the autosomal dominant genotypes, and the possibility of ill defined X linked forms.

  15. Trading Places: Mary Shelley’s Argument with Domestic Space

    Directory of Open Access Journals (Sweden)

    Eve M. Lynch

    2013-04-01

    Full Text Available When Mary Shelley began writing The Last Man in 1824 in the wake of her husband Percy Bysshe Shelley’s untimely death, she drew from her close circle of family and friends as models for her main characters. Although it is tempting to view this novel as an autobiographical expiation of the profound sorrow that overwhelmed Shelley at her husband’s death, to do so is to underestimate her prescient political insight and to risk overlooking the complex implications of class and rank that suffuse the position of the narrator, Lionel Verney. While Shelley’s emotions give a passionate appeal to this novel, her intellectual ideas infuse the novel’s powerful critique of British governance. The Last Man is narrated in a political framework in which war and the clash of empires, parliamentary and republican conflict, turbulent revolution, and social and political corruption arrange the fates of the characters. In addition, the plague that silently and invisibly takes over Western Europe and England serves as a spectral process of corrosive malignity from outside, ensnaring all efforts to fix a domestic English system that is collapsing around individuals and the collective.

  16. Sleep disorders in Charcot-Marie-Tooth disease type 1.

    Science.gov (United States)

    Boentert, Matthias; Knop, Katharina; Schuhmacher, Christine; Gess, Burkhard; Okegwo, Angelika; Young, Peter

    2014-03-01

    Obstructive sleep apnoea (OSA) and restless legs syndrome (RLS) have been reported in Charcot-Marie-Tooth disease (CMT) type 1A and axonal subtypes of CMT, respectively. The aim of this case-control study was to investigate both prevalence and severity of OSA, RLS and periodic limb movements in sleep (PLMS) in adult patients with genetically proven CMT1. 61 patients with CMT1 and 61 insomnic control subjects were matched for age, sex, and Body Mass Index. Neurological disability in patients with CMT was assessed using the Functional Disability Scale (FDS). RLS diagnosis was based on a screening questionnaire and structured clinical interviews. All participants underwent overnight polysomnography. OSA was present in 37.7% of patients with CMT1 and 4.9% of controls (psleep quality. In addition to known risk factors, CMT may predispose to OSA. RLS is highly prevalent not only in axonal subtypes of CMT but also in primarily demyelinating subforms of CMT. PLMS are common in CMT1, but do not significantly impair sleep quality.

  17. Restaging Hysteria: Mary Wigman as Writer and Dancer

    Directory of Open Access Journals (Sweden)

    Laura A. McLary

    2003-06-01

    Full Text Available Mary Wigman was not only a leading proponent of the early twentieth-century Expressionist dance movement, but also a writer of poetry and short poetic prose. Despite her assertion that dance was beyond language, she wrote often about dance in an attempt to articulate the kinesthetic experience of dance through languages. This interdisciplinary study explores the intersection of dance and writing for Wigman, focusing on gender coding in writing and dance within the context of early twentieth-century dialogues. Despite the pervasive equation of (feminine hysteria with dance and (masculine subjectivity with authorship, Wigman engaged in both activities. I argue that Wigman is able to reclaim and redefine the "hysteria" of the dance experience through writing about dance. In her dance poetry, the act of looking at herself in a mirror as she dances allows Wigman to circumvent the traditional objectification through the male gaze experienced by the female dancer. Through the act of writing, Wigman asserts her subjectivity, taking control of the out-of-body experience of dance creation.

  18. Municipio Mariño Estado Nueva Esparta

    Directory of Open Access Journals (Sweden)

    María Medina

    2008-01-01

    Full Text Available Se caracteriza la gastronomía típica margariteña como atractivo turístico del Municipio Mariño, sus componentes: restaurantes, autores, platos y promoción. Para formular recomendaciones que permitan su aprovechamiento. Los fundamentos teóricos se basan en el área turismo y gastronomía, y su importancia para la actividad. La metodología es descriptiva y su diseño es de campo. Como conclusión se tiene que la situación actual de la gastronomía típica margariteña como atractivo turístico del municipio se caracteriza por la falta de información y promoción, la cual no se está aprovechando como atractivo turístico debido a la falta de conocimiento sobre la gastronomía típica margariteña y donde además en los restaurantes del municipio se están modificando las recetas originales.

  19. Maris Jesse: loodan südamest, et ükski haigla ei pikenda järjekordi / Maris Jesse ; intervjueerinud Liisa Past

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    Tervishoiuspetsialist, Tervise Arengu Instituudi juht Maris Jesse vastab küsimustele, mis puudutavad haiglavõrgu arengukava võimalikku ümbertegemist, tervishoiusüsteemis olevaid kokkuhoiukohti, HIV-nakkuse levikut ning meetmeid selle piiramiseks ja ennetamiseks majanduskriisi tingimustes, samuti reformi vajalikkust ravkindlustuses

  20. Teekond kogunemisest koostööni / Ene Kulasalu, Ene Velström, Koidu Tani-Jürisoo, Mari Karm ; vahendas Mari Karm

    Index Scriptorium Estoniae

    2003-01-01

    Vestlusringis on Avatud Meele Instituudi koolitajad Ene Kulasalu, Ene Velström, Koidu Tani-Jürisoo ja Mari Karm, et arutada koostöö ja selle juhtimise võimalikkust ja vajalikkust, grupi arengufaaside (sõltuvusfaas, konfliktifaas, eraldumisfaas, koostööfaas) toimimist ja nende teadvustamise tähtsust

  1. Exploiting natural fracture and fault fairways in the Jean Marie carbonate platform

    Energy Technology Data Exchange (ETDEWEB)

    Wierzbicki, R.; Todorovic-Maranic, D [EnCana Corp., Calgary, AB (Canada)

    2010-07-01

    The Jean Marie carbonate is an Upper Devonian aged carbonate platform that developed on the western margin of North America. The Jean Marie is an under pressured, low permeability, slightly fractured limestone, and is rarely dolomitic. Dry gas is trapped in a regional stratigraphic trap as the Jean Marie changes laterally up dip into a thin tight mudstone. To minimize damage to the fine pore system in this under-pressured reservoir, the pool has been developed using underbalanced horizontal drilling. Advanced seismic techniques are being utilized to detect porosity zones and high permeability fairways which increase deliverability and recovery of gas from the Jean Marie carbonate. Variable well productivity has been observed in similar facies, as has high productivity in low porosity rock. This presentation reviewed the nature of fractures in the Jean Marie from thin section to the seismic scale and focus on the seismic methods utilized to detect and exploit these high permeability fairways. The paper provided a geological overview of the region and identified previous studies. The paper also reviewed drilling results and production indicators of fracture flow. The controls on fracturing were also discussed. It was concluded that of the 109 wells drilled in the study area, 44 encountered significant permeability enhancements associated with open fractures and leached carbonates. 14 refs., 21 figs.

  2. Greater Sierra Jean Marie tight gas carbonate : multidisciplinary approach drives decade of development

    Energy Technology Data Exchange (ETDEWEB)

    Bialowas, S.A.; Temple, C.A.; Aminu, M.O. [EnCana Corp., Calgary, AB (Canada)

    2010-07-01

    This paper presented the exploration and development of the Jean Marie Member, a tight gas-saturated carbonate, located in northeast British Columbia. This large concentrated gas resource is known to have a repeatable exploitation method of underbalanced horizontal wells. EnCana has converted from nitrogen foam to drilling with natural gas. This paper discussed the regional Jean Marie geology, including deposition, facies, reservoir characteristics, and gas volumes-in-place. It also discussed the chronology of the exploration and development of the Jean Marie play from the 1960s to present. Most of the data analysed and presented was from Encana. The paper also summarized the five key drivers influencing the successful exploitation of the Jean Marie, including its dominant land position on quality acreage; highly-connected multi-disciplinary teams; repeatable yet evolving processes; awareness and application of new technologies; and rigorous tracking and discipline. The future development in the Greater Sierra Jean Marie is supported by a large inventory of multi-lateral horizontal wells, executed using the gas factory model. refs., figs., appendices.

  3. Mary McAuliffe. Twilight of the Belle Epoque: The Paris of Picasso, Stravinsky, Proust, Renault, Marie Curie, Gertrude Stein, and Their Friends through the Great War. Lanham, MD: Rowman and Littlefield. 2014. vii + 418 pp.

    Directory of Open Access Journals (Sweden)

    Eric Martone

    2015-01-01

    Full Text Available Review of Mary McAuliffe. Twilight of the Belle Epoque: The Paris of Picasso, Stravinsky, Proust, Renault, Marie Curie, Gertrude Stein, and Their Friends through the Great War . Lanham, MD: Rowman and Littlefield. 2014. vii + 418 pp.

  4. Correlations between silicic volcanic rocks of the St Mary's Islands (southwestern India) and eastern Madagascar

    DEFF Research Database (Denmark)

    Melluso, Leone; Sheth, Hetu C.; Mahoney, John J.

    2009-01-01

    The St Mary's, Islands (southwestern India) expose silicic volcanic and sub-volcanic rocks (rhyolites and granophyric dacites) emplaced contemporaneously with the Cretaceous igneous province of Madagascar, roughly 88-90 Ma ago. I he St Mary's Islands rocks have phenocrysts of plagioclase...... and isotopic Compositions very close to those of rhyolites exposed between Vatomandry Ilaka and Mananjary in eastern Madagascar, and are distinctly different from rhyolites front other sectors of the Madagascan province. We therefore postulate that the St Mary's and the Vatomandry-Ilaka Mananjary silicic rock...... outcrops were adjacent before the Late Cretaceous rifting that split Madagascar from India, If so, they provide a valuable tool to check and aid traditional Cretaceous India Madagascar reconstructions based on palaeomagnetism, matching Precambrian geological features, and geometric fitting of continental...

  5. Biomechanical effects of sensorimotor orthoses in adults with Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Wegener, Caleb; Wegener, Katrin; Smith, Richard; Schott, Karl-Heinz; Burns, Joshua

    2016-08-01

    Charcot-Marie-Tooth disease is an inherited neuropathy causing progressive weakness, foot deformity and difficulty walking. Clinical anecdotes suggest orthoses designed on the 'sensorimotor' paradigm are beneficial for improving gait in Charcot-Marie-Tooth disease. Investigate the effect of sensorimotor orthoses on in-shoe and lower limb biomechanics in adults with Charcot-Marie-Tooth disease. Randomised, repeated-measures, exploratory study. Eight males and two females with Charcot-Marie-Tooth disease aged 31-68 years fitted with pedorthic shoes and custom-made sensorimotor orthoses were randomly tested at baseline and after 4 weeks of adaptation. In-shoe three-dimensional multi-segment foot and lower limb kinematics and kinetics were collected as were plantar pressures, electromyography and self-reported comfort, stability, cushioning and preference. Compared to the shoe only condition, sensorimotor orthoses increased midfoot eversion and plantarflexion, increased ankle eversion and produced small but significant changes at the knee and hip indicating increased internal rotation. The orthoses increased medial ground reaction forces and increased pressure at the heel, midfoot and toes. There were minimal effects on electromyography. The sensorimotor orthoses were rated higher for comfort, cushioning, stability and preference. Sensorimotor orthoses produced changes in kinematic, kinetic and pressure variables in adults with Charcot-Marie-Tooth disease and were regarded as more comfortable, cushioned and stable during walking. In this study, the walking ability of patients with Charcot-Marie-Tooth disease improved with the use of foot orthoses designed according to the sensorimotor paradigm. However, the mechanism of action appears to be primarily mechanical in origin. Randomised controlled trials are necessary to evaluate the long-term patient-reported outcomes of sensorimotor orthoses. © The International Society for Prosthetics and Orthotics 2015.

  6. Sister Mary Joseph Nodules on 99mTc HYNIC-TOC scintigraphy in patients with neuroendocrine tumors.

    Science.gov (United States)

    Jing, Hongli; Zhang, Yingqiang; Li, Fang

    2015-02-01

    A Sister Mary Joseph nodule represents an umbilical metastasis, which is more commonly caused by a primary malignancy in gastrointestinal tract or from reproductive system. We report Sister Mary Joseph nodules caused by neuroendocrine tumor and revealed on Tc HYNIC-TOC scintigraphy.

  7. Rundum artist-run space and its elusive form / Hanna Laura Kaljo, Mari-Leen Kiipli, Kulla Laas ... [jt.

    Index Scriptorium Estoniae

    2015-01-01

    Rundum on 2013. a septembris Tallinnas loodud liikuv loominguline platvorm, mille eesmärgiks on suhestuda erinevate kohtadega, reageerida tühikutele Eesti loomemaastikus ning uurida sealjuures ka omaalgatuslike praktikate võimalikkust kohalikus kontekstis. Vestlusringis Rundumi algatajad Mari-Leen Kiipli, Kulla Laas, Aap Tepper, Mari Volens, Kristina Õllek

  8. ReUse Republic annab mõistele "uuskasutus" uue tähenduse / Tanel Veenre, Mari Klein

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Moe- ja disainiagentuuri KalaMari uuest kaubamärgist ReUse Republic. Tegu on seisma jäänud brändirõivaste ümberdisainimise ja (uus)kasutusega. Projekti looja Mari Martin, kaasatud 15 eesti disainerit

  9. Mary's Case: An Illustration of Interprofessional Collaborative Practice for a Child With Severe Disabilities.

    Science.gov (United States)

    Ogletree, Billy T; Brady, Nancy; Bruce, Susan; Dean, Evan; Romski, MaryAnn; Sylvester, Lorraine; Westling, David

    2017-05-17

    The principles of interprofessional collaborative practice (IPCP) are illustrated through the case of Mary, a child with severe disabilities. Mary's experiences from early childhood to young adulthood are highlighted by both optimal and less-than-ideal examples of clinical services and collaborative practice. The range of collaboration illustrates potential variations in service delivery. Thematic comments and resources are provided by professionals experienced with and committed to IPCP who represent the following four disciplines: occupational therapy, physical therapy, special education, and speech-language pathology. Although potentially challenging, IPCP is a dynamic practice methodology appropriate for speech-language pathologists and others serving persons with severe disabilities.

  10. M-ary suprathreshold stochastic resonance in multilevel threshold systems with signal-dependent noise

    Science.gov (United States)

    Cheng, Chaojun; Zhou, Bingchang; Gao, Xiao; McDonnell, Mark D.

    2017-08-01

    We investigate multilevel threshold systems with signal-dependent noise that transmit a common random input signal. We demonstrate the occurrence of M-ary suprathreshold stochastic resonance caused by the signal-dependent noise, and quantify the information enhancement that results relative to the absence of noise. We also find that in the case of M-ary threshold systems, the values of mutual information and signal-to-quantization-noise ratio are larger than the corresponding values in the case of binary threshold systems. These results are potentially useful for understanding the encoding mechanism of inner-ear hair cells and other biological sensory systems.

  11. Learning to Honour Their Body and Blood : pilgrims on the Path of Mary Magdalene

    OpenAIRE

    Fedele, Anna

    2006-01-01

    This article describes the beliefs and some of the ritual practices of a group of female pilgrims visiting places in France and Catalonia that they associate with the figure of Mary Magdalene. It pays particular attention to the pilgrim’s process of learning ways to relate to her own body and to her menstrual cycle. Drawing elements from neo-paganism these women reinterpret the meaning of Christian symbols and places. They consider Mary Magdalene both as a forerunner of feminism and as a mode...

  12. Mary Mallon (1869-1938) and the history of typhoid fever.

    Science.gov (United States)

    Marineli, Filio; Tsoucalas, Gregory; Karamanou, Marianna; Androutsos, George

    2013-01-01

    Mary Mallon was born in 1869 in Ireland and emigrated to the US in 1884. She had worked in a variety of domestic positions for wealthy families prior to settling into her career as a cook. As a healthy carrier of Salmonella typhi her nickname of "Typhoid Mary" had become synonymous with the spread of disease, as many were infected due to her denial of being ill. She was forced into quarantine on two separate occasions on North Brother Island for a total of 26 years and died alone without friends, having evidently found consolation in her religion to which she gave her faith and loyalty.

  13. 1970. aastatel alustas arhitektidest sõprade ja kolleegide rühm... / Mari Laanemets

    Index Scriptorium Estoniae

    Laanemets, Mari, 1975-

    2008-01-01

    27.VI avatakse Eesti Arhitektuurimuuseumis Rotermanni soolalaos 1970. ja 1980. alguse eksperimentaalset arhitektuuripraktikat käsitlev näitus "Keskkond, objektid, kontseptsioonid. Tallinna kooli arhitektid 1972-1985". Näha saab Ülevi Eljandi, Ignar Fjuki, Veljo Kaasiku, Tiit Kaljundi, Vilen Künnapu, Leonhard Lapini, Avo-Himm Looveere, Kristin-Mari Looveere, Marika Lõokese, Jüri Okase, Jaan Olliku, Ain Padriku, Toomas Reinu, Andres Ringo, Sirje Runge, Harry Sheini, Tõnis Vindi ja Matti Õunapuu töid. Näituse kuraatorid Andres Kurg ja Mari Laanemets. Samas: "Uue arhitektuuri näituse programm" (1972)

  14. 'BRS Mari': nova cultivar de pimenta dedo-de-moça para processamento 'BRS Mari': new hot pepper cultivar for processing

    Directory of Open Access Journals (Sweden)

    Sabrina Isabel C de Carvalho

    2009-12-01

    Full Text Available 'BRS Mari' é uma nova cultivar de pimenta dedo-de-moça desenvolvida para uso múltiplo, como produto in natura, processada na forma de molho líquido ou desidratada em flocos, moída junto com as sementes, para a produção de pimenta tipo 'calabresa'. A cv. 'BRS Mari' foi desenvolvida a partir da população 'CNPH 0039' por meio de seis ciclos de seleção massal com autofecundação controlada. A nova cultivar apresenta plantas de polinização aberta com hábito de crescimento intermediário, com aproximadamente 90 cm de altura e 1,25 m de largura, com resistência múltipla a doenças, com destaque para o virus Pepper Yellow Mosaic Virus (PepYMV e nematóide das galhas (Meloidogyne javanica, resistência mediana ao oídio (Oidium sicula, mancha bacteriana (Xanthomonas spp. e antracnose (Colletotrichum spp.. A colheita dos frutos tem início cerca de 70 dias após o transplante. Nas condições da região Centro-Oeste, 'BRS Mari' apresentou boa uniformidade de planta, ótima qualidade de fruto e grande potencial produtivo, alcançando 35 t ha-1 em seis meses, quando cultivada no espaçamento de 1 m entre plantas e 1,5 m entre linhas. Os frutos são alongados e pendentes, típicos do tipo dedo-de-moça, com passagem de coloração verde claro, amarelo com antocianina e laranja quando imaturos e vermelho intenso quando maduros, com aproximadamente 6,0 cm de comprimento, 1,4 cm de largura e cerca de 1,7 mm de espessura da parede. A principal característica da 'BRS Mari' é o elevado teor de capsaicina, aproximadamente 90.000 SHU (Unidades de Calor Scoville, mais elevado quando comparada com outras cultivares do mesmo grupo.'BRS Mari' is a new hot pepper cultivar suitable for processing as sauce or dehydrated flakes, ordinarily known in Brazil as 'calabresa' type, as well as for fresh market. Hot pepper cv. 'BRS Mari' was obtained from population 'CNPH 0039', through six cycles of mass selection with controlled selfing of selected plants. The

  15. REGARDS PRISMATIQUES DES PERSONNAGES DE MARIE NDIAYE (COMÉDIE CLASSIQUE ET LADIVINE (Prismatic looks of the characters of Marie NDiaye (Comédie classique and Ladivine

    Directory of Open Access Journals (Sweden)

    Andreea-Madalina Neamtu Voicu

    2015-06-01

    Full Text Available Among the oddities that populate the literary world of Marie NDiaye, there is one aspect that plays on the subjectivity of the perspective. This is something that binds two novels of Marie NDiaye apparently totally different. Comédie classique (1987 is written in the first person, with one focalizer who attributes words, gestures, thoughts to those around him. In Ladivine (2013, the writer multiplies voices and glances: there are five perspectives that alternate. Each focalizer works like a prism that breaks the reader’s vision of the characters. The image of the protagonists is therefore built on the tension between the vision of oneself and others, between the desire to appear and the sometimes opaque reality, between the visible and the invisible.

  16. Mary Mitchell Slessor (1848 – 1915) and Her Impact on the ...

    African Journals Online (AJOL)

    ... promoting women's rights, rescuing unwanted children and protecting native children. She died on 13 January, 1915 (aged 66) at Use Ikot Oku, Calabar, Nigeria. Beyond contribution to knowledge, this brief work is a legacy of Mary Mitchell Slessor's contributions to the evangelization of Nigeria and Church History.

  17. Walt Disney Meets Mary Daly: Invention, Imagination, and the Construction of Community.

    Science.gov (United States)

    Covino, William A.

    2000-01-01

    Posits Walt Disney as an influential sorcerer in the process of integrating the real world into Disney's synthetic universe, and Mary Daly's work "Wickedary" as a work that constructs an alternative "magic kingdom" through an insistence on an anti-patriarchal lexicon. (NH)

  18. Hand involvement in children with Charcot-Marie-Tooth disease type 1A

    NARCIS (Netherlands)

    Burns, Joshua; Bray, Paula; Cross, Lauren A.; North, Kathryn N.; Ryan, Monique M.; Ouvrier, Robert A.

    2008-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A), a demyelinating neuropathy characterised by progressive length-dependent muscle weakness and atrophy, is thought to affect the foot and leg first followed some time later by hand weakness and dysfunction. We aimed to characterise hand Strength, function

  19. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  20. Response to Marie Paz Morales' ``Influence of culture and language sensitive physics on science attitude achievement''

    Science.gov (United States)

    Cole, Mikel Walker

    2015-12-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript.

  1. Auditory processing in patients with Charcot-Marie-Tooth disease type 1A.

    NARCIS (Netherlands)

    Neijenhuis, C.A.M.; Beynon, A.J.; Snik, A.F.M.; Engelen, B.G.M. van; Broek, P. van den

    2003-01-01

    HYPOTHESIS: It is unclear whether Charcot-Marie-Tooth (CMT) disease, type 1A, causes auditory processing disorders. Therefore, auditory processing abilities were investigated in five CMT1A patients with normal hearing. BACKGROUND: Previous studies have failed to separate peripheral from central

  2. Mary S. Peake and Charlotte F. Forten: Black Teachers during the Civil War and Reconstruction

    Science.gov (United States)

    Taylor, Kay Ann

    2005-01-01

    The teaching lives of Mary S. Peake and Charlotte L. Forten during the Civil War and Reconstruction through a limited life history approach are examined. It is a contribution to the roles of African American women in the history of American education.

  3. The Gendering of Albert Einstein and Marie Curie in Children's Biographies: Some Tensions

    Science.gov (United States)

    Wilson, Rachel E.; Jarrard, Amber R.; Tippins, Deborah J.

    2009-01-01

    Few twentieth century scientists have generated as much interest as Albert Einstein and Marie Currie. Their lives are centrally depicted in numerous children's biographies of famous scientists. Yet their stories reflect interesting paradoxes and tacit sets of unexplored sociocultural assumptions about gender in science education and the larger…

  4. PARTNER: A Marie Curie Initial Training Network for hadron therapy (with french subtitles)

    CERN Multimedia

    CERN BULLETIN; Manuela Cirilli; Nathalie Hospital

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  5. PARTNER: A Marie Curie Initial Training Network for hadron therapy (with english subtitles)

    CERN Multimedia

    CERN BULLETIN; Manuela Cirilli; Nathalie Hospital

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  6. Neuromuscular Hip Dysplasia in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Bamford, Nigel S.; White, Klane K.; Robinett, Stephanie A.; Otto, Randolph K.; Gospe, Sidney M., Jr.

    2009-01-01

    Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting 36 in 100,000 people. CMT type 1A (hereditary motor and sensory neuropathy) is the most frequent form of this disease, affecting 60 to 80% of the CMT population, but its diagnosis may be delayed because of inconsistent clinical signs and…

  7. Women, Education and the Material Body Politic in Mary Wollstonecraft's "Vindications"

    Science.gov (United States)

    Bernath, Elizabeth

    2016-01-01

    This paper discusses Mary Wollstonecraft's "A Vindication of the Rights of Woman: With Strictures on Political and Moral Subjects" and "A Vindication of the Rights of Men" as books of philosophy about rational materialism. Based on an analysis of Lockean thought, as applied to the possibility of women's development of reason,…

  8. Living Proof: What Helen Keller, Marilyn Monroe, and Marie Curie Have in Common.

    Science.gov (United States)

    Saul, E. Wendy

    1986-01-01

    Examines biographies of Marie Curie written for children and discusses two types of distortions: simple misrepresentations of fact and selective retelling of the past. It is concluded that biographies of minority or female success should deal specifically with strategies used by the hero or heroine to combat prejudice. (EM)

  9. Attracting Talented Researchers to Ireland: A review of The European Marie Curie Programme

    OpenAIRE

    GIORDANI, SILVIA

    2007-01-01

    PUBLISHED The purpose of this publication is to illustrate how researchers in academia and industry in Ireland have successfully secured funding from Europe in the Marie Curie Programme and to highlight the impact this has had in furthering their R&D ambitions.

  10. Pedagogies and Literacies, Disentangling the Historical Threads: An Interview with Bill Cope and Mary Kalantzis

    Science.gov (United States)

    Cope, Bill; Kalantzis, Mary; Smith, Anna

    2018-01-01

    In this discussion with educational researchers and New London Group conveners, Bill Cope and Mary Kalantzis, we discuss the origins, life, and future of the New London Group's multiliteracies framework. We reflect on the initial goals the group had over 20 years ago for more equitable schooling opportunities, and what is yet to be done to reach…

  11. Online Opportunist: Mary Ellen Icaza--Montgomery County Public Libraries, Rockville, MD

    Science.gov (United States)

    Library Journal, 2004

    2004-01-01

    When Mary Ellen Icaza became Electronic Services Librarian at Montgomery County Public Libraries, she noticed that the readers' services information on the library web site was invisible, even to librarians. "And if staff can't find it," she says, "customers can't." She set out to help people find that material-and to turn a…

  12. The Marie Curie Actions at CERN – reaching out beyond particle physics and Europe

    CERN Multimedia

    EU Projects Office

    2014-01-01

    The European Commission’s Marie Curie Actions have been a pillar of the EU Framework Programmes for several decades as a means of promoting career development and enhancing mobility of researchers in Europe. This corresponds nicely to one of CERN’s main missions: to train the next generation of scientists and engineers.   The European Commissioner for Education, Culture, Multilingualism, Sport, Media and Youth, Androulla Vassiliou (centre) met the Marie Curie Fellows on her visit to CERN in April 2013. CERN has been pleased to be a major player in the Marie Curie Actions under the Sixth and Seventh Framework Programmes (FP6 from 2002 to 2006 and FP7 from 2007 to 2013), being one of the most successful participants in Europe. Under FP7, CERN was ranked first in Switzerland and fifth in Europe against stiff competition in terms of overall funding. Participation was in all of the Marie Curie Actions: Initial Training Networks, Industry-Academia Partnership Pathways, IRSES, CO...

  13. Charcot-Marie-Tooth Disease in a Child with Acute Lymphoblastic ...

    African Journals Online (AJOL)

    Alasia Datonye

    Patients with Charcot-Marie-Tooth disease may show severe toxicities with vincristine. It is therefore recommended that an extensive neurologic examination should be conducted on any paediatric patient with a diagnosis of malignancy to ... the Paediatric oncology unit of the University of Port. Harcourt, teaching hospital ...

  14. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  15. Kunsti kuumtöötlus Läti aladel / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Pedvale vabaõhumuuseumis toimunud rahvusvahelisest workshop'ist teemal "Kompost", mille tulemusi presenteeriti 6. VIII 2004. Ignas Kazakeviciuse, Jurate Rakeviciute, Diana Dimzha-Dime, Ule Björn Gundermanni, Remo Randveri, Maris Grosbahsi, Andrus Joonase töödest

  16. Migrating to the City: Negotiating Gender and Race in Marie Arana's "Lima Nights"

    Science.gov (United States)

    Heredia, Juanita

    2016-01-01

    This article examines Peruvian-American Marie Arana's second novel "Lima Nights" (2008) in which she represents Amazonian indigenous migrations to Lima, Peru during and after the Shining Path civil war years (1986-2006). As part of a generation of transnational US Latina authors in the post-2000 period, Arana recovers the image of the…

  17. Mary Lincoln's Madness: Understanding the Factors that Influence the Diagnosis and Treatment of Bipolar Disorder

    Science.gov (United States)

    Dick, Carina; Renes, Susan L.; Strange, Anthony T.

    2010-01-01

    Mary Lincoln, wife of President Abraham Lincoln, lived a tragic life. Beginning with the death of her mother when she was a little girl, Mrs. Lincoln experienced a number of family deaths, including three brothers, three sons, and the murder of her beloved husband while she sat by his side. In addition to tragedy, Mrs. Lincoln suffered from poor…

  18. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  19. TOURISM PLANNING OPPORTUNITIES FOR THE SALT LAKES OF OCNELE MARI AND OCNIŢA

    Directory of Open Access Journals (Sweden)

    POPESCU ANTOANETA-CARINA

    2012-03-01

    Full Text Available Tourism Planning Opportunities for The Salt Lakes of Ocnele Mari and Ocniţa. Ocnele Mari used to be a popular balneal tourism destination in the Southern region of Romania, Oltenia. Due to the hilly climate and the two balneal establishments of Ocnele Mari and Ocniţa, tourists could find the necessary natural cure factors for rheumatic and cardiovascular diseases. However, the salt from Ocnele Mari was also used for industrial purposes, being extracted through solution mining, which proved to be detrimental to the environment. Salt underground dissolution caused land subsidence and landslide in the area, together with the formation of large salt lakes. Security became an issue, the number of tourists diminished and the balneal equipment became obsolete because of lack of modernization investment. Under these circumstances, on the basis of field work, we have reached the conclusion that a better planning of the resort and of the salt lakes would contribute to the economic development of the region.

  20. Dr. Mary McLeod Bethune: A Life Devoted to Service

    Science.gov (United States)

    Long, Kim Cliett

    2011-01-01

    The purpose of this paper is to explore and analyze the leadership traits of Dr. Mary McLeod Bethune, an African-American woman of history, using the servant leadership theory developed by Robert K. Greenberg and the ten characteristics of servant leadership as conceived by Larry C. Spears. This exploration seeks to identify the significant…

  1. The Marie Curie programme at the Institute of Archaeology 2004-2008

    Directory of Open Access Journals (Sweden)

    Thilo Rehren

    2008-09-01

    Full Text Available The Marie Curie Early Stage Training (MEST projects, run by the European Commission, offer training opportunities to young scientists from EU member states and sometimes also from non-European countries. The Institute of Archaeology hosted one such project between 2004 and 2008, which is described here by its Principal Investigator.

  2. Sotsiaalset kaitset võib vajada igaüks / Maris Jesse, Anu Toots, Tõnis Kõiv

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    Sotsiaalpoliitika asjatundjad Eesti sotsiaalsüsteemi probleemidest ja arenguteedest. Vestlusringist võtsid osa Tervise Arengu Instituudi direktor Maris Jesse, Tallinna Ülikooli riigiteaduste instituudi võrdleva halduspoliitika professor Anu Toots ja Riigikogu sotsiaalkomisjoni liige Tõnis Kõiv. Vestlusringi juhtis RiTO peatoimetaja Helle Ruusing

  3. A REACTION TO SISTER MARY EDWARD DOLAN'S LINGUISTICS IN TEACHING READING.

    Science.gov (United States)

    BARNHART, CLARENCE L.

    A REACTION TO SISTER MARY EDWARD DOLAN'S ARTICLE, "EFFECTS OF A MODIFIED LINGUISTICS AND WORD RECOGNITION PROGRAM ON FOURTH-GRADE READING ACHIEVEMENT," WHICH APPEARED IN THE "READING RESEARCH QUARTERLY" AND WHICH DESCRIBES THE RESULTS OF A 3-YEAR EXPERIMENT IN TEACHING READING WITH A BASAL SYSTEM TO A CONTROL GROUP OF 10 CLASSROOMS AND TEACHING…

  4. The design and research of anti-color-noise chaos M-ary communication system

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Yongqing, E-mail: fuyongqing@hrbeu.edu.cn; Li, Xingyuan; Li, Yanan [College of information and Communication Engineering, Harbin Engineering University, Harbin 150001 (China); Zhang, Lin [College of Underwater Acoustic Engineering, Harbin Engineering University, Harbin 150001 (China)

    2016-03-15

    Previously a novel chaos M-ary digital communication method based on spatiotemporal chaos Hamilton oscillator has been proposed. Without chaos synchronization circumstance, it has performance improvement in bandwidth efficiency, transmission efficiency and anti-white-noise performance compared with traditional communication method. In this paper, the channel noise influence on chaotic modulation signals and the construction problem of anti-color-noise chaotic M-ary communication system are studied. The formula of zone partition demodulator’s boundary in additive white Gaussian noise is derived, besides, the problem about how to determine the boundary of zone partition demodulator in additive color noise is deeply studied; Then an approach on constructing anti-color-noise chaos M-ary communication system is proposed, in which a pre-distortion filter is added after the chaos baseband modulator in the transmitter and whitening filter is added before zone partition demodulator in the receiver. Finally, the chaos M-ary communication system based on Hamilton oscillator is constructed and simulated in different channel noise. The result shows that the proposed method in this paper can improve the anti-color-noise performance of the whole communication system compared with the former system, and it has better anti-fading and resisting disturbance performance than Quadrature Phase Shift Keying system.

  5. Assessing a Couple's Relationship and Compatibility Using the MARI[R] Card Test and Mandala Drawings

    Science.gov (United States)

    Frame, Phyllis G.

    2006-01-01

    This paper illustrates the use of the MARI[R] Card Test, a transpersonal assessment tool which includes archetypal designs and color choices, as well as the drawing of a white and black mandala, or circle picture, for assessing the compatibility of two people in a committed relationship. In an informal pilot research study, 22 couples were given…

  6. Uus nobelist : prantslane Jean-Marie Gustave Le Clézio / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2008-01-01

    Nobeli kirjandusauhind 2008 - prantsuse romaanikirjanik Jean-Marie Gustave Le Clézio. Sisaldab autori eesti keelde tõlgitud teoste annotatsioone: Päev, mil Beaumont tegi tutvust oma valuga : [novell] / tlk. Merike Riives (kogumikust Prantsuse novell, 1973); Kõrb / tlk. Kristiina Ross (Eesti Raamat, 1990); Diego ja Frida / tlk. Sirje Keevallik (Kunst, 2007)

  7. Marie Underi ühe luuletuse ümber / August Eelmäe

    Index Scriptorium Estoniae

    Eelmäe, August, 1931-

    2003-01-01

    Marie Underi luuletusest "Me ootame" ja selle vaheredaktsioonist, avaldatud pealkirjaga "Üks päev" (Oma Maa, 1947, nr. 2). Ilmunud ka kogumikus: Eelmäe, August. Kõned ja kirjatööd. Tallinn : Underi ja Tuglase Kirjanduskeskus, 2006, lk. 56-71

  8. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri

    2003-01-01

    Concordia Ülikooli rektori kohast loobunud Mart Susi ning prorektori ametikohalt lahkunud Mari-Ann Susi taotlevad neile kuuluvat ülikooli pidanud miljonivõlgades firma pankrotti. Hiljuti loodi õppejõududest, tudengitest js töötajatest mittetulundusühing Concordia Akadeemiline Ühisus (CAU), selle nõukogu esimees on Hagi Šein

  9. Re-Birthing the Monstrous: James Whale's (Mis)Reading of Mary Shelley's "Frankenstein."

    Science.gov (United States)

    Picart, Caroline Joan S.

    1998-01-01

    Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine…

  10. Strangers and Orphans: Knowledge and Mutuality in Mary Shelley's "Frankenstein"

    Science.gov (United States)

    Gomez, Claudia Rozas

    2013-01-01

    Paulo Freire consistently upheld humanization and mutuality as educational ideals. This article argues that conceptualizations of knowledge and how knowledge is sought and produced play a role in fostering humanization and mutuality in educational contexts. Drawing on Mary Shelley's novel "Frankenstein," this article focuses on the…

  11. Rediscovering the Art of Developmental Therapy: An Interview with Mary M. Wood

    Science.gov (United States)

    Teagarden, James M.; Kaff, Marilyn S.; Zabel, Robert H.

    2013-01-01

    Dr. Mary Margaret Wood is best known for developing psychoeducational programs that integrate mental health and special education interventions for children with emotional and behavioral disorders (EBD). Developmental Therapy (DT) includes comprehensive assessment of student behavior, communication, social, and cognitive development,…

  12. Novels, Thought Experiments, and Humanist Sociology in the Classroom: Mari Sandoz and CAPITAL CITY.

    Science.gov (United States)

    Hill, Michael R.

    1987-01-01

    Based upon the teaching of Mari Sandoz' allegorical novel, CAPITAL CITY, this article identifies the characteristics of novels which provide a sociologically useful humanist perspective. A key characteristic is the extent to which the novel conducts thought experiments, defined as cerebral exercises which explore alternative social futures based…

  13. Acoustic Characteristics of Stressed Front Vowels in the French speech of Russian and Mari people

    Directory of Open Access Journals (Sweden)

    Зоя Георгиевна Зорина

    2014-12-01

    Full Text Available The article describes the spectral characteristics of stressed front vowels in the French speech of native speakers, Russian, Hill and Meadow Mari speakers under conditions of «artificial» bilingualism. Vowel spectra were determined by the F-picture (the first two formants. The research revealed that Russian and Mari native speakers demonstrate an ability to differentiate the rise of French vowels more frequently. Correct pronunciation of a number of French vowels is observed more frequently in the speech of the Hill Mari, more rarely- in the speech of the Meadow Mari. Russian speakers hardly differentiate vowel rows. However, the "poor" quality of speech in a foreign language does not prevent one from good understanding due to the fact that for a bilingual speaker the sounding of tokens on the morphemic level becomes less relevant than the meaning. Sufficiently deep immersion into lifestyle, behavior of speakers of another language can help achieve a real image of the picture of another language.

  14. Unheralded Historian: Mary Sheldon Barnes and Primary Source Material in History Books

    Science.gov (United States)

    Chisholm, James A., Jr.

    2013-01-01

    In the latter part of the nineteenth century, Mary Sheldon Barnes emerged as a leading historical methods professor and history textbook author. Although men dominated the field, she wrote several articles and books alone or with her husband Earl Barnes about primary source materials and teaching. She lived during an era in United States history…

  15. Mari sangari päeva sõnum / Jaak Prozes ; interv. Livia Viitol

    Index Scriptorium Estoniae

    Prozes, Jaak, 1965-

    2006-01-01

    Fenno-Ugria Hõimukeskuse juhataja ja Eestimaa Rahvaste Ühenduse juht soome-ugri rahvaste olukorrast Venemaal ja rahvusseltside tegevusest Eestis. Aprilli lõpul tähistasid marid oma rahvuspüha - mari sangari päeva. Pärimuse põhjal langes maride rahvuskangelane Boltu̧ võitluses oma rahva vabaduse eest 26. aprillil 1556

  16. Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing.

    LENUS (Irish Health Repository)

    Murphy, Sinead M

    2012-07-01

    Charcot-Marie-Tooth disease (CMT) is a clinically and genetically heterogeneous group of diseases with approximately 45 different causative genes described. The aims of this study were to determine the frequency of different genes in a large cohort of patients with CMT and devise guidelines for genetic testing in practice.

  17. Muuga / Mary von Grünewaldt ; tõlk. Mati Sirkel

    Index Scriptorium Estoniae

    Grünewaldt, Mary von

    2004-01-01

    Leo Zoegelt ostetud Muuga mõisahoone korrastamisest ja uue hoone ehitamisest C. T. von Neffi kunstikogu paigutamise tarbeks. Tütre mälestused. Tõlgitud raamatust: Skizzen und Bilder aus dem Leben Carl Timoleon von Neff / Mary von Grünewaldt. Darmstadt, 1887

  18. Chest Injury in Children in Amman – Jordan | Abu-Rish | Mary ...

    African Journals Online (AJOL)

    Chest injuries in children are increasing and is a cause of significant mortality. Chest injuries are common in our country, specially in school age group. Public awareness is mandatory to reduce the incidence of these injuries. Key Words: chest injuries, penetrating and blunt injury, children. Mary Slessor Journal of Medicine ...

  19. Õpilaste uurimistööd said raamatuks / Maris Saagpakk, Janika Kärk

    Index Scriptorium Estoniae

    Saagpakk, Maris

    2004-01-01

    2003. aasta aprillis toimunud saksa keele olümpiaadi lõppvooru pääsenud tööde valikkogumik: Bekannte Deutschbalten aus meinem Heimatort : Schülarbeiten Deutscholympiade 2003 / Maris Saagpakk, Janika Kärk (Hrsg.). Tallinn, 2004

  20. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    Directory of Open Access Journals (Sweden)

    Jan Whitaker

    2017-02-01

    Full Text Available In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  1. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    OpenAIRE

    Jan Whitaker

    2017-01-01

    In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  2. Difficulties in teaching electromagnetism: an eight year experience at Pierre and Marie Curie University

    Directory of Open Access Journals (Sweden)

    H. Roussel

    2012-07-01

    Full Text Available We will begin by outlining the details of how electromagnetics are taught in the  electrical engineering program offered at Pierre and Marie Curie University (a French example from the undergraduate to the Masters degree levels.  We will also discuss how our methods are and should be adapted to teach waves propagation without discouraging students.

  3. Magic Women on the Margins: Ec-Centric Models in Mary Poppins and Ms Wiz

    Science.gov (United States)

    Valverde, Cristina Perez

    2009-01-01

    This paper offers a comparative analysis of two characters belonging to the tradition of empowered "spinster" in children's fiction, namely Mary Poppins and Ms Wiz, from the perspective of gender politics and child/adult interactions. A distinction is made between the figure portrayed in P. L. Travers' texts and the Disney film starring Julie…

  4. Gait patterns of children and adolescents with Charcot-Marie-Tooth disease.

    NARCIS (Netherlands)

    Wojciechowski, E.; Sman, A.D.; Cornett, K.; Raymond, J.; Refshauge, K.; Menezes, M.P.; Burns, J.

    2017-01-01

    Gait abnormalities reported in childhood Charcot-Marie-Tooth disease (CMT) include foot-drop, reduced ankle power at push-off and increased knee and hip flexion for swing clearance ('steppage-gait'). The purpose of this study was to describe the gait patterns of 60 children aged 6-17 years with CMT

  5. Natural history of Charcot-Marie-Tooth disease during childhood.

    Science.gov (United States)

    Cornett, Kayla M D; Menezes, Manoj P; Shy, Rosemary R; Moroni, Isabella; Pagliano, Emanuela; Pareyson, Davide; Estilow, Timothy; Yum, Sabrina W; Bhandari, Trupti; Muntoni, Francesco; Laura, Matilde; Reilly, Mary M; Finkel, Richard S; Eichinger, Kate J; Herrmann, David N; Bray, Paula; Halaki, Mark; Shy, Michael E; Burns, Joshua

    2017-09-01

    To determine the rate of disease progression in a longitudinal natural history study of children with Charcot-Marie-Tooth (CMT) disease. Two hundred six (103 female) participants aged 3 to 20 years enrolled in the Inherited Neuropathies Consortium were assessed at baseline and 2 years. Demographic, anthropometric, and diagnostic information were collected. Disease progression was assessed with the CMT Pediatric Scale (CMTPedS), a reliable Rasch-built linearly weighted disability scale evaluating fine and gross motor function, strength, sensation, and balance. On average, CMTPedS Total scores progressed at a rate of 2.4 ± 4.9 over 2 years (14% change from baseline; p < 0.001). There was no difference between males and females (mean difference, 0.5; 95% confidence interval [CI], -0.9 to 1.9; p = 0.49). The most responsive CMTPedS items were dorsiflexion strength (z-score change, -0.3; 95% CI, -0.6 to -0.05; p = 0.02), balance (z-score change, -1.0; 95% CI, -1.9 to -0.09; p = 0.03), and long jump (z-score change, -0.4; 95% CI, -0.7 to -0.02; p = 0.04). Of the most common genetic subtypes, 111 participants with CMT1A/PMP22 duplication progressed by 1.8 ± 4.2 (12% change from baseline; p < 0.001), 9 participants with CMT1B/MPZ mutation progressed by 2.2 ± 5.1 (11% change), 6 participants with CMT2A/MFN2 mutation progressed by 6.2 ± 7.9 (23% change), and 7 participants with CMT4C/SH3TC2 mutations progressed by 3.0 ± 4.5 (12% change). Participants with CMT2A progressed faster than CMT1A (mean difference, -4.4; 95% CI, -8.1 to -0.8; p = 0.02). Children with CMT1A progressed consistently through early childhood (3-10 years) and adolescence (11-20 years; mean difference, 1.1; 95% CI, -0.6 to 2.7; p = 0.19), whereas CMT2A appeared to progress faster during early childhood than adolescence (mean difference, 10.0; 95% CI, -2.2 to 22.2; p = 0.08). Using the CMTPedS as an outcome measure of disease severity, children

  6. Identificação diferencial de Rhodococcus equi e Dietzia maris em bubalinos Differential identification of Rhodococcus equi and Dietzia maris in buffaloes

    Directory of Open Access Journals (Sweden)

    L.R. Viana

    2009-08-01

    Full Text Available Foram analisados 24 isolados bacterianos oriundos de leite e pele de búfalas (Bubalus bubalis, os quais foram previamente identificados como Rhodococcus equi com o auxílio de fenotipia concisa. Testes fenotípicos complementares e ferramentas moleculares foram utilizados com o objetivo de caracterizar esses isolados, bem como diferenciá-los de outros microrganismos intimamente relacionados. Observaram-se três fenótipos distintos, porém a identificação dos isolados foi inconclusiva. Apenas um dos isolados foi comprovado como sendo R. equi com a realização da PCR espécie-específica, sequenciamento e análise dos fragmentos de DNA. Os demais isolados só foram identificados pelo sequenciamento de fragmento do gene que codifica a região 16S do rRNA universal de bactérias, indicando tratar-se de Dietzia maris. O perfil de susceptibilidade aos antimicrobianos revelou maior resistência dos isolados de D. maris para oxacilina (96% e rifampicina (87%. O isolado de R. equi apresentou resistência à amicacina, oxacilina, penicilina, rifampicina e tetraciclina. Alerta-se para o risco da incorreta identificação dos isolados baseados em testes fenotípicos concisos e para a necessidade de utilização de testes complementares para diferenciação entre R. equi e D. maris.Twenty-four bacterial isolates from milk and skin of buffalo females (Bubalus bubalis, which previously had been identified as Rhodococcus equi by using a restricted number of phenotypical tests for bacterial characterization, were analyzed. The goal of this study was to perform the characterization of these isolates, as well as the differentiation of other microorganisms closely related by using additional phenotypical tests and molecular tools. Based on the phenotypical results, three different biotypes were obtained. However, the identification of the isolates was inconclusive. Only one of the isolates was confirmed as R. equi by the PCR specifically for this species, as

  7. Marcel Mariën’s 'Woman Ajar'. A case of minor photography?

    Directory of Open Access Journals (Sweden)

    Mieke Bleyen

    2010-12-01

    Full Text Available

     

    Abstract (E: This paper examines Woman Ajar (1985, a late, largely forgotten photo book by Marcel Mariën, one of the key figures of Belgian post war surrealism. Representing the female body as fragmented and alienated by small objects, Mariën’s photographs balance between the private (amateurish and the public (professional and explores the fragile border between art and pornography. In addition, there is a sense of belatedness in them, which makes them particularly hard to label. This paper proposes the concept of minor photography, borrowed from Gilles Deleuze and Felix Guattari’s concept of a minor literature, as a valuable tool to approach Marcel Mariën’s work, which risks slipping through art history’s net.

    Abstract (F: Cet article examine Woman Ajar (1985, un livre de photographie tardif et largement oublié de Marcel Mariën, l’une des figures clés du surréalisme belge d’après-guerre. Représentant le corps féminin comme fragmenté et aliéné par de petits objets, les photographies de Mariën balancent entre les sphères privée (amateur et publique (professionnelle et explorent la frontière fragile entre l’art et la pornographie. En outre, il y a en elles un sens de la tardiveté, qui les rend particulièrement difficiles à étiqueter. Cet article propose le concept de photographie mineure, emprunté au concept de littérature mineure avancé par Gilles Deleuze et Félix Guattari, comme un outil précieux permettant d’approcher l’œuvre de Marcel Mariën, qui court le risque de glisser au travers du filet de l’histoire de l’art.

  8. Management Plan for Protection and Monitoring of Lake Ladora, Lake Mary and Lower Derby Lake During RMA Remediation

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This management plan further defines the conditions that are required to be maintained in Lake Ladora, Lake Mary, and Lower Derby Lake to meet the requirements of...

  9. [Mari Uusküla. Basic colour terms in Finno-Ugric and Slavonic Languages] / Galina Paramei

    Index Scriptorium Estoniae

    Paramei, Galina

    2010-01-01

    Arvustus: Uusküla, Mari. Basic colour terms in Finno-ugric and Slavonic languages: myths and facts. Tartu : Tartu University Press, 2008. Dissertationes linguisticae Universitatis Tartuensis, 1406-5657 ; 9

  10. [Mari Laanemets. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978] / Mara Traumane

    Index Scriptorium Estoniae

    Traumane, Mara

    2013-01-01

    Arvustus: Laanemets, Mari. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978. (Humboldt-Schriften zur Kunst- und Bildgeschichte, Bd. 14.9 Berlin: Gebr. Mann 2011

  11. Pahede koht on ajaloo prügikastis! Kas ikka on? / Andres Maimik, Maris Jesse ; intervjueerinud Sigrid Kõiv

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    2009-01-01

    Proua Evelin Ilves tegi ettepaneku, et arstid võiksid inimesi innustada isikliku eeskujuga ja viia ennast tervislikku vormi. Filmimees Andres Maimik ja terviseedendaja Maris Jesse arutavad, kas on võimalik pahelisi eluviise välja juurida

  12. Armastus kui vale(m) : Mari Vihmandi ooperi "Armastuse valem" lavastusest Estonias / Ester Võsu ja Kristel Pappel

    Index Scriptorium Estoniae

    Võsu, Ester, 1975-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  13. Mida arvatakse omavalitsustes koolivõrgu optimeerimisest? / Mart Järvik, Maris Liiders, Peeter Aas, Kaarin Veinbergs

    Index Scriptorium Estoniae

    2012-01-01

    Arvamust avaldasid Järvakandi vallavanem, Raplamaa omavalitsuste liidu esimees Mart Järvik, Harju maavalitsuse haridus- ja sotsiaalosakonna juhataja Maris Liiders, Põlva maavalitsuse haridus- ja sotsiaalosakonna juhataja Peeter Aas, Ida-Viru maavalitsuse haridus- ja sotsiaalosakonna juhataja Kaarin Veinbergs

  14. Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater

    Directory of Open Access Journals (Sweden)

    Natalia Fernández

    2016-01-01

    Full Text Available Reseña de Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater, Waco (Texas, Baylor University Press, 2012, 173 pp. ISBN: 9781602586451.

  15. I Want to Believe: A Short Psychobiography of Mary Baker Eddy.

    Science.gov (United States)

    Dean, Taylor Wilson

    2016-01-01

    The 18th and 19th centuries were beset with new religious movements in the United States: Shakers, Latter Day Saints, Millerites, and Seventh Day Adventists to name a few. One group, Christian Science, held radically different views than their counterparts and their origins lay in the most unlikely of places, a perpetually ill and poor woman from New Hampshire. Much has been said about Mary Baker Eddy: some say that she was a prophet, others that she was a fraud. Herein no such judgments are made. This study seeks to look into the life of Mary Baker Eddy from a psychological lens in the hopes that insight can be gained into the founding of the First Church of Jesus Christ Scientist and perhaps to allay the binary of Mrs. Eddy as either prophet or fanatic.

  16. The research school of Marie Curie in the Paris faculty, 1907-14.

    Science.gov (United States)

    Davis, J L

    1995-07-01

    As the most famous woman scientist of the twentieth century, there has been no shortage of books and articles on the life and career of Marie Curie (1867-1934). Her role as director of a laboratory-based research school in the new scientific field of radioactivity, a field which embraced both chemistry and physics, however, has never been examined. In recent years, there has been a growing interest in the question of research schools, and Morrell, Ravetz, Geison, and Klosterman, amongst others, have written on this subject. Using, in part, the methodology of Morrell, this paper investigates the role of Marie Curie as a school director in the Paris Faculty in the years 1907-14, examining the work and characteristics of her school and assessing her effectiveness as a director.

  17. Umbilical metastasis (Sister Mary Joseph's nodule diagnosed by fine-needle aspiration

    Directory of Open Access Journals (Sweden)

    Tatomirović Željka

    2004-01-01

    Full Text Available Sister Mary Joseph’s nodule is the eponym for metastatic involvement of the umbilicus. This less common entity is the sign of disseminated malignant disease, mainly of digestive and gynecologic origin, and is associated with a poor prognosis. A case of Sister Mary Joseph’s nodule in a 76-year-old woman in whom the umbilical metastasis was the first sign of malignant disease in presented. The diagnosis of metastatic adenocarcinoma was established by fine needle aspiration cytology of the umbilical nodule. Radiological and ultrasonographic investigation disclosed carcinoma of the gallbladder with pancreas, stomach, and colon invasion as well as peritoneal dissemination. The diagnosis was confirmed by exploratory laparatomy and histological examination of the excised umbilical nodule.

  18. Flower Power: Desire, Gender, and Folk Belief in the Joycean Mary Garden

    Directory of Open Access Journals (Sweden)

    Christin Mulligan

    2017-06-01

    Full Text Available Robert Brazeau and Derek Gladwin’s Eco-Joyce (2014 largely overlooks a historical basis for ecocritical thought. The absence of a historicist view requires consideration not only of the natural world but folk botany, such as the Mary Garden that is a phantom presence in A Portrait of the Artist as a Young Man as well as in “Nausicaa” and “Penelope” in Ulysses and Finnegans Wake. The undergrowth of the garden reconfigures human action and subtly predicts it with its compendium of theological and devotional meanings for the burgeoning sexuality expressed by Gerty MacDowell and Issy Earwicker as well as the mature longing of Molly Bloom. This essay will establish a fresh Deleuzian paradigm of Becoming-Flower to demonstrate how the Mary Garden blooms to present new perspectives on Catholicism, eros, and gender identity in Joyce’s major works.

  19. OCNELE MARI-OCNIŢA, VÂLCEA COUNTY RESOURCES, EXPLOITATION, RISKS, UTILISATION

    Directory of Open Access Journals (Sweden)

    P. GÂŞTESCU

    2015-03-01

    Full Text Available Ocnele Mari-Ocniţa. Resources, exploitation, risks, valorization. In Ocnele Mari Town and its constituent locality - Ocniţa, Vâlcea County, following the extraction of a large volume of salt through its underground dissolution, the soil and the breccias covering the salt have become unstable, producing landfalls and landslides that affected the exploitation installations, the transport infrastructure and several homes, during the last decennia, especially in the area of Ocniţa locality. In order to avoid major imbalances in this geographic area, following the mining activities, and also in order to reduce the consequences of the pollution triggered by saltwater, the main affected areas-locations have been identified and analyzed. This paper presents the resources existing in the exploitation area, the modifications occurred following the salt mining activities and their effects on: economic efficiency, local population, environmental balance, tourist potential and utilisation.

  20. Agonia peruana no século XX: Mariátegui e Flores Galindo

    Directory of Open Access Journals (Sweden)

    Marcus Vinícius Furtado da Silva Oliveira

    2016-02-01

    Full Text Available O presente artigo procura analisar a presença de traumas e ressentimentos na sociedade peruana do século XX a partir da leitura dos ensaios de José Carlos Mariátegui e Alberto Flores Galindo. Em nossas análises, pretendemos demonstrar como a conquista e a colonização se configuram como experiências traumáticas para os autores, que propõe modos de gestão dos ressentimentos advindos desses traumas. Abstract The presente work aims to analyze the presence of traumas and resentments in Peruvian society on the XX century parting from the lectures of the essays written by José Carlos Mariátegui and Alberto Flores Galindo. In this analyzes, we pretend to demonstrate how conquest and colonization are comprehended as traumatic experiences by the authors, that proposes ways of handling the resentments originated by these traumas.

  1. Controversial Questions of the Early Neolithic Studies in the Mari Volga Region

    Directory of Open Access Journals (Sweden)

    Vybornov A.A.

    2017-03-01

    Full Text Available The article considers some debatable questions of cultural identity, origin and correlation between the different Neolithic sites in the territory of the Mari Volga region, located at the junction of forest-steppe Volga River, Sura River and Lower Kama areas as well as the Upper Volga. The Early Neolithic of this region is characterized by presence of pottery without ornamentation and stroke ware. In the Late Neolithic, the sites with the pottery of Kama culture and of pit-comb type were spread there. The author suggests his own version of development of Neolithic cultures in this region, based on typological approaches and the results of radiocarbon dating and technological analysis of the pottery. Spread of ware without ornamentation seems to be preceding the stroke ware, and both traditions in the Mari land were under the cultural impact of the forest-steppe Volga population.

  2. Detection Performance of M-ary Relay Trees with Non-binary Message Alphabets

    CERN Document Server

    Zhang, Zhenliang; Pezeshki, Ali; Moran, William; Howard, Stephen D

    2012-01-01

    We study the detection performance of $M$-ary relay trees, where only the leaves of the tree represent sensors making measurements. The root of the tree represents the fusion center which makes an overall detection decision. Each of the other nodes is a relay node which aggregates $M$ messages sent by its child nodes into a new compressed message and sends the message to its parent node. Building on previous work on the detection performance of $M$-ary relay trees with binary messages, in this paper we study the case of non-binary relay message alphabets. We characterize the exponent of the error probability with respect to the message alphabet size $\\mathcal D$, showing how the detection performance increases with $\\mathcal D$. Our method involves reducing a tree with non-binary relay messages into an equivalent higher-degree tree with only binary messages.

  3. [Marie Curie, née Maria Sklodowska (1867-1934)--contribution to the development of radiology].

    Science.gov (United States)

    Babić, Rade R; Babić, Gordana Stanković

    2011-01-01

    Marie Curie, née Maria Sklodowska, was born on November 7, 1867 in Warsaw (Poland). She suffered from leukaemia and died on June 4, 1934. She was buried with full honours at Pantheon. Marie Curie and her husband Pierre Curie discovered the radioactive elements Polonium (84Po210), Thorium (90Th232) and Radium (88Ra226). Marie Curie introduced the term radioactivity into science. She was the first woman who got Ph.D. in France, the first woman professor at Sorbonne, Paris and Medical Academy. Of all the women who have ever won the Nobel Prize, Marie Curie was the only who received it twice. During World War I Marie Curie designed a mobile x-ray room "radiologic car". Marie Curie had an x-ray machine installed into a car and demonstrated how to use its dynamo for electric power production necessary for the x-ray machine to work. She had 20 cars with moving radiological lab made and trained 150 people to work on them. She brought something radically new into military medicine--mobile x-ray diagnostics. With the discovery of radioactive elements a new medical branch, radiotherapy, was developed.

  4. Rapport de frais de 2017-2018 pour Mary Anne Chambers | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rapport de frais de 2017-2018 pour Mary Anne Chambers. Total des frais de déplacement : CAD$14,462.99. Constatation de l'impact de la recherche en Afrique de l'Est. 2 juillet 2017 au 12 juillet 2017. CAD$12,528.71. Réunion du Conseil des gouverneurs. 18 juin 2017 au 21 juin 2017. CAD$1,145.57. Représenter le ...

  5. Rapport de frais de 2016-2017 pour Mary Anne Chambers | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rapport de frais de 2016-2017 pour Mary Anne Chambers. Total des frais de déplacement : CAD$9,584.36. Réunion du Conseil des gouverneurs. 19 mars 2017 au 22 mars 2017. CAD$1,289.85. Assister au Cours de l'École de la fonction publique du Canada sur les sociétés d'État. 28 novembre 2016 au 29 novembre ...

  6. Mary A. Favret, War at a Distance: Romanticism and the Making of Modern Wartime: a Review

    OpenAIRE

    Jackson, Noel B.

    2010-01-01

    Mary Favret’s War at a Distance: Romanticism and the Making of Modern Wartime is a brilliant, beautifully written book on the experience of war in British Romantic writing. Offering intricate close readings of Cowper, Wordsworth, Austen, Coleridge, and others, Favret situates these canonical writers in relation to large historical contexts: writings in a prophetic mode by Robert Brothers and Captain Charles W. Pasley, 18th century weather history, and British paintings of colonial India, to n...

  7. The Historical Threshold : Crisis, Ritual and Liminality in Sofia Coppola’s Marie-Antoinette (2006

    Directory of Open Access Journals (Sweden)

    Anna Backman Rogers

    2012-10-01

    Full Text Available Marie Antoinette does not pertain to any of the narrative tropes and standards set by the conventional historical drama. Rather, it is a film about the politicisation of the female body. Its focus on the rite of passage of a young girl into adulthood in an extreme situation is, in effect, highly political both in its effort to convey a specifically female subjectivity and in its eschewal of a more traditional treatment of its subject matter.

  8. Exploring variation-aware contig graphs for (comparative) metagenomics using MaryGold

    Science.gov (United States)

    Nijkamp, Jurgen F.; Pop, Mihai; Reinders, Marcel J. T.; de Ridder, Dick

    2013-01-01

    Motivation: Although many tools are available to study variation and its impact in single genomes, there is a lack of algorithms for finding such variation in metagenomes. This hampers the interpretation of metagenomics sequencing datasets, which are increasingly acquired in research on the (human) microbiome, in environmental studies and in the study of processes in the production of foods and beverages. Existing algorithms often depend on the use of reference genomes, which pose a problem when a metagenome of a priori unknown strain composition is studied. In this article, we develop a method to perform reference-free detection and visual exploration of genomic variation, both within a single metagenome and between metagenomes. Results: We present the MaryGold algorithm and its implementation, which efficiently detects bubble structures in contig graphs using graph decomposition. These bubbles represent variable genomic regions in closely related strains in metagenomic samples. The variation found is presented in a condensed Circos-based visualization, which allows for easy exploration and interpretation of the found variation. We validated the algorithm on two simulated datasets containing three respectively seven Escherichia coli genomes and showed that finding allelic variation in these genomes improves assemblies. Additionally, we applied MaryGold to publicly available real metagenomic datasets, enabling us to find within-sample genomic variation in the metagenomes of a kimchi fermentation process, the microbiome of a premature infant and in microbial communities living on acid mine drainage. Moreover, we used MaryGold for between-sample variation detection and exploration by comparing sequencing data sampled at different time points for both of these datasets. Availability: MaryGold has been written in C++ and Python and can be downloaded from http://bioinformatics.tudelft.nl/software Contact: d.deridder@tudelft.nl PMID:24058058

  9. Reversing Eve’s curse: Mary Magdalene Pilgrims and the creative ritualization of menstruation

    OpenAIRE

    Fedele, A.

    2014-01-01

    This article is about the creative ritual practices of a group of Spanish and Catalan pilgrims who visit French shrines dedicated to Saint Mary Magdalene. Raised and educated in Catholic families, these women describe themselves as being part of the worldwide Goddess movement and do not consider their theories and rituals to be in conflict with Christian values. During their pilgrimages they celebrate rituals in shrines that they feel were unjustly monopolized by the “Church”. The pilgrims se...

  10. Feeling vs vorm. White label : Under Marie. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2007-01-01

    Rockansambli Chungin and the Strap-On-Faggots ja soome punkbändi Rejects kontserdist Tallinnas Reggae Baaris. Heliplaadist: Under Marie "1. What What? 2. What What?". Heliplaatidest: Zahir "Green means go", Ry Cooder "My name is Buddy", Ladysmith Black Mambazo "Warner Bros. Collection", Macy Gray "Big", Nneka "Victim of Truth", "Grinderman", Stooges "The Weirdness", "The Good, The Bad and the Queen", Marco Di Marco "In New York, My Poetry", Kaiser Chiefs "Yours Truly, Angry Mob", Mika "Life in cartoon motion"

  11. Mariátegui e a ocidentalização da política Mariátegui and the occidentalization of politics

    Directory of Open Access Journals (Sweden)

    Ricardo Melgar Bao

    2007-05-01

    Full Text Available A contribuição de Mariátegui para pensar o socialismo na América Latina é resgatada por meio das críticas à marginalização cultural e política dos povos não-ocidentais, bem como do particular uso que deu ao marxismo, acentuando-lhe as características universais através da apropriação cultural dos diversos contextos. Palavras-chave: América Latina. Oriente. Ocidente. Marxismo. Socialismo. Civilização. Cultura. Identidade. The contribution of Mariátequi for the view of socialism in Latin America is recovered not only through the criticism of the cultural and political marginal position of the non-western people but also through the particular way he used marxism, reinforcing its universal characteristics by the cultural appropriation of different cultural contexts. Keywords: Latin America. East. West. Marxism. Socialism. Civilization. Culture. Identity.

  12. XAS studies of the effectiveness of iron chelating treatments of Mary Rose timbers

    Energy Technology Data Exchange (ETDEWEB)

    Berko, A; Schofield, E J; Chadwick, A V [School of Physical Sciences, University of Kent, CT2 7NR (United Kingdom); Smith, A D [STFC Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Jones, A M [The Mary Rose Trust, HM Naval Base, Portsmouth, PO1 3LX (United Kingdom); Mosselmans, J F W, E-mail: a.berko@kent.ac.u [Diamond Light Source, Didcot, OX11 0DE (United Kingdom)

    2009-11-15

    The oxidation of sulfur in marine archaeological timbers under museum storage conditions is a recently identified problem, particularly for major artefacts such as historic ships excavated from the seabed. Recent work on the Vasa has stressed the role of iron in catalysing the oxidative degradation of the wood cellulose and the polyethylene glycols used to restore mechanical integrity to the timbers. In developing new treatment protocols for the long term preservation of Henry VIII of England's flagship, the Mary Rose, we are investigating the potential of chelating agents to neutralise and remove the iron products from the ships timbers. We have explored the use of aqueous solutions of chelating agents of calcium phytate, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA) and ammonium citrate to extract the iron compounds. All of these solutions exhibit some level of iron removal; however the key is to find the most effective concentration at pH of around 7 of the reagent solution, to minimise the treatment time and find the most cost-effective treatment for the whole of the Mary Rose hull. Fe K-edge XAFS data from samples of Mary Rose timbers, before and after treatment by the chelating agents mentioned has been collected. The data collected provide valuable insights into the effectiveness of the treatment solutions.

  13. Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Sevilla, Teresa; Lupo, Vincenzo; Martínez-Rubio, Dolores; Sancho, Paula; Sivera, Rafael; Chumillas, María J; García-Romero, Mar; Pascual-Pascual, Samuel I; Muelas, Nuria; Dopazo, Joaquín; Vílchez, Juan J; Palau, Francesc; Espinós, Carmen

    2016-01-01

    Charcot-Marie-Tooth disease (CMT) is a complex disorder with wide genetic heterogeneity. Here we present a new axonal Charcot-Marie-Tooth disease form, associated with the gene microrchidia family CW-type zinc finger 2 (MORC2). Whole-exome sequencing in a family with autosomal dominant segregation identified the novel MORC2 p.R190W change in four patients. Further mutational screening in our axonal Charcot-Marie-Tooth disease clinical series detected two additional sporadic cases, one patient who also carried the same MORC2 p.R190W mutation and another patient that harboured a MORC2 p.S25L mutation. Genetic and in silico studies strongly supported the pathogenicity of these sequence variants. The phenotype was variable and included patients with congenital or infantile onset, as well as others whose symptoms started in the second decade. The patients with early onset developed a spinal muscular atrophy-like picture, whereas in the later onset cases, the initial symptoms were cramps, distal weakness and sensory impairment. Weakness and atrophy progressed in a random and asymmetric fashion and involved limb girdle muscles, leading to a severe incapacity in adulthood. Sensory loss was always prominent and proportional to disease severity. Electrophysiological studies were consistent with an asymmetric axonal motor and sensory neuropathy, while fasciculations and myokymia were recorded rather frequently by needle electromyography. Sural nerve biopsy revealed pronounced multifocal depletion of myelinated fibres with some regenerative clusters and occasional small onion bulbs. Morc2 is expressed in both axons and Schwann cells of mouse peripheral nerve. Different roles in biological processes have been described for MORC2. As the silencing of Charcot-Marie-Tooth disease genes have been associated with DNA damage response, it is tempting to speculate that a deregulation of this pathway may be linked to the axonal degeneration observed in MORC2 neuropathy, thus adding a

  14. Marys Lake 69/115-kV transmission line upgrade and substation expansion projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    Western Area Power Administration (Western) and the Platte River Power Authority (Platte River) propose to upgrade portions of the existing electric transmission and substation system that serves the Town of Estes Park, Colorado. The existing transmission lines between the Estes Power Plant Switchyard and the Marys Lake Substation include a 115,000 volt (115-kV) line and 69,000 volt (69-kV) line. Approximately one mile is a double-circuit 115/69-kV line on steel lattice structures, and approximately two miles consists of separate single-circuit 115-kV and a 69-kV lines, constructed on wood H-Frame structures. Both lines were constructed in 1951 by the US Bureau of Reclamation. The existing transmission lines are on rights-of-way (ROW) that vary from 75 feet to 120 feet and are owned by Western. There are 48 landowners adjacent to the existing ROW. All of the houses were built adjacent to the existing ROW after the transmission lines were constructed. Upgrading the existing 69-kV transmission line between the Marys Lake Substation and the Estes Power Plant Switchyard to 115-kV and expanding the Marys Lake Substation was identified as the most effective way in which to improve electric service to Estes Park. The primary purpose and need of the proposed project is to improve the reliability of electric service to the Town of Estes Park. Lack of reliability has been a historical concern, and reliability will always be less than desired until physical improvements are made to the electrical facilities serving Estes Park.

  15. Geothermal heating project at St. Mary's Hospital, Pierre, South Dakota. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-12-01

    St. Mary's Hospital, Pierre, South Dakota, with the assistance of the US Department of Energy, drilled a 2176 ft well into the Madison Aquifer ot secure 108/sup 0/F artesian flow water at 385 gpm (475 psig shut-in pressure). The objective was to provide heat for domestic hot water and to space heat 163,768 sq. ft. Cost savings for the first three years were significant and, with the exception of a shutdown to replace some corroded pipe, the system has operated reliably and continuously for the last four years.

  16. Mariátegui, el escritor vanguardista contemporáneo

    Directory of Open Access Journals (Sweden)

    Álvaro Campuzano Arteta

    2005-10-01

    Full Text Available Este ensayo rememora el encuentro ocurrido a inicios del siglo XX entre la literatura vanguardista y el socialismo. Recorriendo un camino que va de los comentarios de José Carlos Mariátegui sobre el cine de Charlie Chaplin, a la exploración de la narrativa vanguardista de Martín Adán, la reflexión aquí propuesta se funda en el pensamiento de Walter Benjamin. Para la elaboración de este trabajo se han desarrollado algunas de las secciones de una tesis de maestría escrita para el Dartmouth College.

  17. [Carbamazepine-sensitive neuromyotonia and Charcot-Marie-Tooth disease of the neuronal type].

    Science.gov (United States)

    Serratrice, G; Pouget, J; Pellissier, J F; Cros, D

    1989-01-01

    Following an anti-smallpox vaccination a 17 year-old boy developed spontaneous muscular activity with cramps and fasciculations in the lower limbs. There was distal amyotrophy of the lower limbs and pes cavus. Clinical signs suggested a cholinergic hyperfunction. EMG showed a significant spontaneous activity and was neurogenic in the lower limbs. Nerve conduction velocities were consistent with axonal damage. Muscular biopsy showed aspects of chronic denervation. Neuromyotonia disappeared with carbamazepine treatment. This case can be added to the reported associations of neuromyotonia and Charcot-Marie-Tooth disease. Such cases are an additional argument for the axonal origin of neuromyotonia.

  18. Ciencia e industria en el desarrollo de la radiactividad: el caso de Marie Curie

    OpenAIRE

    Roqué, Xavier

    1997-01-01

    Not available.Se argumenta que Marie Curie desarrolló sus investigaciones en radiactividad en estrecha relación con la industria de los radioelementos. Esta relación incluyó desde el desarrollo de procedimientos de extracción para diversas sustancias radiactivas, hasta la promoción de su propio laboratorio industrial. La actividad industrial de Curie se aviene mal con su imagen heroica de científica pura, sacrificada y carente de medios, imagen que, paradójicamente, se retrotrae a las campaña...

  19. [Comparison of Chuvashs with Maris and Russians by vital statistics and the Crow index].

    Science.gov (United States)

    El'chinova, G I; Zinchenko, R A; Zinchenko, S P; Ginter, E K

    2002-01-01

    Genetic demographic characteristics were calculated for Chuvash and Russian inhabitants of the Republic of Chuvashia. The generation lengths were 27.09 and 26.4 years and the sibship sizes were 2.54 and 1.82 for Chuvashes and Russians, respectively. Crow's indices and their components were as follows: Im = 0.05, If = 0.31, and Itot = 0.37 for Chuvashes and Im = 0.03, If = 0.43, and Itot = 0.46 for Russians. The genetic demographic characteristics obtained were compared with those for Highland and Meadow Maris.

  20. The intellectual legacy of Mary Neth's work on farm women and rural communities.

    Science.gov (United States)

    Osterud, Grey

    2009-01-01

    Mary Neth's 1995 book, "Preserving the Family Farm: Women, Community, and the Foundations of Agribusiness in the Midwest, 1900-1940," made a major contribution to the analysis of the connections between gender and the political economy that shaped farm women's lives and fueled farmers' resistance to the transformation of rural life wrought by agribusiness. Focusing on the processes of negotiation between women and men in farming families and rural communities, Neth illuminated the relationship between women's work and their power. Tracing the dense networks that connected farm families, she also showed how cooperation in work generated and sustained radical farm movements.

  1. Reflecting on the Legacy of Economist Bernard Maris: A Call to Action

    OpenAIRE

    Errouaki, Karim

    2015-01-01

    I was shocked to learn that Bernard Maris had been murdered at a meeting of the editors of Charlie Hebdo in Paris on 7 January 2015. He died at his desk; killed by the fanaticism that he regularly denounced. http://rift26.centerblog.net/ Can we prevent potential Charlie Hebdo Paris 7-1-like attacks? For France and its people, and even the whole world, there seems to be no other answers to this question: 7-1-like attacks must be prevented. One might say: We will remove terrorists by taking ac...

  2. Low-sampling-rate M-ary multiple access UWB communications in multipath channels

    KAUST Repository

    Alkhodary, Mohammad T.

    2015-08-31

    The desirable characteristics of ultra-wideband (UWB) technology are challenged by formidable sampling frequency, performance degradation in the presence of multi-user interference, and complexity of the receiver due to the channel estimation process. In this paper, a low-rate-sampling technique is used to implement M-ary multiple access UWB communications, in both the detection and channel estimation stages. A novel approach is used for multiple-access-interference (MAI) cancelation for the purpose of channel estimation. Results show reasonable performance of the proposed receiver for different number of users operating many times below Nyquist rate.

  3. Marie Darrieussecq, Rapporto di polizia. Le accuse di plagio e altri metodi di controllo della scrittura

    Directory of Open Access Journals (Sweden)

    Niccolò Scaffai

    2012-04-01

    Full Text Available A Marie Darrieussecq è successo qualcosa di strano. Non è il fatto di essere nata in Francia, a Bayonne, nel 1969. Né di essere una scrittrice (oltre che una studiosa di letteratura e una psicanalista, che ha pubblicato fiction, racconti autobiografici, saggi letterari. Questo non è così strano. Lo è invece il fatto che metà dei suoi romanzi siano stati considerati, da lettori diversi e soprattutto da altri scrittori, prodotti di «imitazione», «copia», «plagio psichico», o addirittura di «sottrazione di manoscritto»

  4. Palvelumuotoilun hyödyntäminen kahvilassa : case: Konditoria Mari

    OpenAIRE

    Niukkanen, Essi

    2013-01-01

    Tämän toiminnallisen opinnäytetyön tarkoituksena on selvittää kuinka palvelumuotoilun eri keinoja voidaan hyödyntää pienyrityksessä. Tavoitteena on kehittää palvelua asiakaslähtöisemmäksi. Toimeksiantajana opinnäytetyössä toimii yksityinen kahvilayritys Konditoria Mari Tampereella. Opinnäytetyöni koostuu kahdesta osasta: teoriaosuudesta ja toiminnallisesta osasta. Teoriaosuudessa avaan työni kannalta olennaisia käsitteitä kuten, palvelun määritelmä, asiakaslähtöisyys ja palvelumuotoilu. T...

  5. Doprinos Mary Parker Follett teoriji organizacije i menadžmenta

    OpenAIRE

    Puđak, Mirna

    2017-01-01

    U ovom se radu prikazuje teorija Mary Parker Follett, inovativne autorice s početka 20. stoljeća, te se analizira njezin doprinos teoriji organizacije i menadžmenta. Njezina izvorna djela najprije se prikazuju kroz pregled ključnih tema o kojima je pisala, a potom se njezina teorija analizira s različitih aspekata. Istražuje se odnos teorije M. P. Follett prema drugim teorijama organizacije, počevši s klasičnom teorijom organizacije kojoj kronološki pripada, a nastavlja se usporedbom sa šk...

  6. Clio goes roller-skating: Images of Memory in some poems by Mary Kennan Herbert Clio goes roller-skating: Images de la mémoire dans quelques poèmes de Mary Kennan Herbert

    Directory of Open Access Journals (Sweden)

    Jennifer Kilgore

    2009-11-01

    Full Text Available A few words about Mary Kennan HerbertMary Kennan Herbert is a writer with midwestern roots. She was born in 1938 in St. Louis, Missouri, and spent most of her childhood there. During her adolescent years she lived in Tennessee. She obtained a University degree in art from Peabody College in Nashville. In New York, she pursued a career as editor in a publishing house until the 1980s, when a merger ended her job security. After several attempts at working for different publishers, she started s...

  7. La tesis de Mariátegui sobre el carácter feudal de la economía colonial peruana Mariátegui's thesis on the feudal character of Peruvian colonial economy

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    2010-06-01

    Full Text Available José Carlos Mariátegui, en su "Esquema de la evolución económica" [del Perú], el primero de los 7 ensayos (1928, consideró que la economía colonial peruana era feudal. En nuestro libro El marxismo de Mariátegui y su aplicación a los '7 ensayos (2005', manifestamos que con la información disponible hoy, tal afirmación se había tornado insostenible. Por su parte, Antonio Melis señaló que la caracterización de Mariátegui podía ser discutida. En este artículo se examinan las observaciones planteadas por Melis. Se considera en primer lugar la posición de A. G. Frank, así como las reacciones que suscitó. Se exponen a continuación las razones en contra de la tesis de Mariátegui sobre el carácter feudal de la economía peruana colonial. Se examina luego la tesis de Ruggiero Romano sobre el feudalismo en general y sobre el iberoamericano en particular. Se realiza, por último, una consideración final.José Carlos Mariátegui, in his "Outline of economic evolution" [Peru], the first of the 7 ensayos (1928, considered Peru's colonial economy was feudal. In our book Mariátegui's Marxism and its application to '7 ensayos' (2005, we said that the information available today, such a claim had become untenable. For his part, Antonio Melis said Mariátegui's characterization could be discussed. This article discusses the observation raised by Melis. It considers the position of A. G. Frank, as well as the reactions to it. Then the reasons against Mariátegui's thesis are also considered. The thesis on feudalism in general and the Latin American one in particular is examined by Ruggiero Romano. A final one consideration is done as a conclusion.

  8. Ideal Beauty in Depicting the Virgin Mary in Florentine Painting in the Second Half of the Fifteenth Century

    OpenAIRE

    Andreja Rakovec

    2008-01-01

    An idealized type of Virgin Mary prevails in Florentine painting of the second half of the fifteenth century. Painters depicted Mary according to Florentine art theory, philosophy, and poetry of the fifteenth century as a woman of physical and spiritual beauty. Ideal female beauty was very precisely defined and it was used not only for images of the Virgin but also for other female figures in art – and, as can be seen from contemporary female portraits, it was also followed by Florentine wome...

  9. The Significance, for Readers in the Twenty-first Century, of the Character of Safie in Mary Shelley's Frankestein

    OpenAIRE

    Esther Katheu Mbithi

    2017-01-01

    The Significance, for Readers in the Twenty-first century, of the Character of Safie in Mary Shelley's Frankenstein. Abstract: This paper presents a critical look at one of the characters in Mary Shelley’s Frankenstein, Safie, through the lenses of a female African scholar in the twenty-first century. A close look at the narrative structure leads to the gradual peeling off of the first two layers, to the core of the narration. The paper looks keenly at a minor character in this core, in the l...

  10. Voice and Body: Emotional Proximity and Physical Distance in Marie de France’s ‘Laustic’

    OpenAIRE

    Zisa, Jessica

    2015-01-01

    Through the lens of feminist theoretical questions and gender studies, this paper explores the relationship between voice and body and the emotional and physical distance that occurs between genders in Marie de France’s Laustic. As a medieval woman writer, Marie provides a textual space to examine the emotional closeness and psychological distance that occurs within the patriarchal structure that delineates gender relations within the convention of marriage. This lai or poetic narrative artic...

  11. Charcot-Marie-Tooth disease: genetic and clinical spectrum in a Spanish clinical series.

    Science.gov (United States)

    Sivera, Rafael; Sevilla, Teresa; Vílchez, Juan Jesús; Martínez-Rubio, Dolores; Chumillas, María José; Vázquez, Juan Francisco; Muelas, Nuria; Bataller, Luis; Millán, José María; Palau, Fancesc; Espinós, Carmen

    2013-10-29

    To determine the genetic distribution and the phenotypic correlation of an extensive series of patients with Charcot-Marie-Tooth disease in a geographically well-defined Mediterranean area. A thorough genetic screening, including most of the known genes involved in this disease, was performed and analyzed in this longitudinal descriptive study. Clinical data were analyzed and compared among the genetic subgroups. Molecular diagnosis was accomplished in 365 of 438 patients (83.3%), with a higher success rate in demyelinating forms of the disease. The CMT1A duplication (PMP22 gene) was the most frequent genetic diagnosis (50.4%), followed by mutations in the GJB1 gene (15.3%), and in the GDAP1 gene (11.5%). Mutations in 13 other genes were identified, but were much less frequent. Sixteen novel mutations were detected and characterized phenotypically. The relatively high frequency of GDAP1 mutations, coupled with the scarceness of MFN2 mutations (1.1%) and the high proportion of recessive inheritance (11.6%) in this series exemplify the particularity of the genetic distribution of Charcot-Marie-Tooth disease in this region.

  12. Flood-inundation maps for the St. Marys River at Decatur, Indiana

    Science.gov (United States)

    Strauch, Kellan R.

    2015-08-24

    Digital flood-inundation maps for an 8.9-mile reach of the St. Marys River at Decatur, Indiana, were developed by the U.S. Geological Survey (USGS), in cooperation with the Indiana Office of Community and Rural Affairs. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site (http://water.usgs.gov/osw/flood_inundation/), depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) of the St. Marys River at Decatur (USGS station number 04181500). The maps are useful for estimating near-real-time areas of inundation by referencing concurrent USGS streamgage information at http://waterdata.usgs.gov/. In addition, the streamgage information was provided to the National Weather Service (NWS) for incorporation into their Advanced Hydrologic Prediction Service flood warning system (http:/water.weather.gov/ahps/). NWS-forecasted peak-stage information may be used in conjunction with the maps developed during this study to show predicted areas of flood inundation.

  13. THE DEAD-LIVING-MOTHER: MARIE BONAPARTE'S INTERPRETATION OF EDGAR ALLAN POE'S SHORT STORIES.

    Science.gov (United States)

    Obaid, Francisco Pizarro

    2016-06-01

    Princess Marie Bonaparte is an important figure in the history of psychoanalysis, remembered for her crucial role in arranging Freud's escape to safety in London from Nazi Vienna, in 1938. This paper connects us to Bonaparte's work on Poe's short stories. Founded on concepts of Freudian theory and an exhaustive review of the biographical facts, Marie Bonaparte concluded that the works of Edgar Allan Poe drew their most powerful inspirational force from the psychological consequences of the early death of the poet's mother. In Bonaparte's approach, which was powerfully influenced by her recognition of the impact of the death of her own mother when she was born-an understanding she gained in her analysis with Freud-the thesis of the dead-living-mother achieved the status of a paradigmatic key to analyze and understand Poe's literary legacy. This paper explores the background and support of this hypothesis and reviews Bonaparte's interpretation of Poe's most notable short stories, in which extraordinary female figures feature in the narrative.

  14. Marie Curie, les femmes et la science, d'hier à aujourd'hui

    CERN Multimedia

    CERN. Geneva; Mariotti, Chiara; Vicinanza, Domenico

    2017-01-01

    Marie Curie, les femmes et la science, d'hier à aujourd'hui Conférence par Hélène Langevin-Joliot Avec la participation de l'Echo du Reculet de Thoiry. L'enregistrement et la liste d'attente sont déjà complets... Mais il n'est pas rare que des personnes réservent et ne viennent pas. Nous réassignerons les places libérées selon la règle "premier arrivé, premier inscrit". Au vu de la forte demande, la conférence sera également disponible en vidéoconférence : lien d'accès "webcast" disponible en bas de cette page. Hélène Langevin-Joliot, directrice de recherche émérite en physique nucléaire fondamentale au CNRS à Orsay, est aussi la fille de Frédéric et Irène Joliot-Curie (prix Nobel de chimie en 1935) et la petite-fille de Pierre Curie (prix Nobel de physique en 1903) et de Marie Curie (prix Nobel de physique en 1903 et prix Nobel de chimie en 1911). Hélène Langevin-Joliot nous parlera de sa vie scientifique, de l’histoire extraordinai...

  15. Marie Curie, les femmes et la science, d'hier à aujourd'hui - English

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Marie Curie, les femmes et la science, d'hier à aujourd'hui Conférence par Hélène Langevin-Joliot Avec la participation de l'Echo du Reculet de Thoiry. L'enregistrement et la liste d'attente sont déjà complets... Mais il n'est pas rare que des personnes réservent et ne viennent pas. Nous réassignerons les places libérées selon la règle "premier arrivé, premier inscrit". Nous envisageons la possibilité de faire un webcast de la conférence. Plus d'information bientôt. Hélène Langevin-Joliot, directrice de recherche émérite en physique nucléaire fondamentale au CNRS à Orsay, est aussi la fille de Frédéric et Irène Joliot-Curie (prix Nobel de chimie en 1935) et la petite-fille de Pierre Curie (prix Nobel de physique en 1903) et de Marie Curie (prix Nobel de physique en 1903 et prix Nobel de chimie en 1911). Hélène Langevin-Joliot nous parlera de sa vie scientifique, de l’histoire extraordinaire de sa famille et en particulier du rôle des ...

  16. Book presentation followed by discussion: "HEP - still an unfeminine profession?" with Mary K Gaillard

    CERN Multimedia

    CERN. Geneva; Gaillard, Mary K

    2016-01-01

    In 1981 Mary K Gaillard became the first woman on the physics faculty at the University of California at Berkeley. Her career as a theoretical physicist spanned the period from the inception — in the late 1960s and early 1970s — of what is now known as the Standard Model of particle physics and its experimental confirmation, culminating with the discovery of the Higgs particle in 2012. Her book A Singularly Unfeminine Profession recounts Gaillard's experiences as a woman in a very male-dominated field, while tracing the development of the Standard Model as she witnessed it and participated in it. Following the book presentation, Prof. Valerie Gibson from the University of Cambridge will comment on her own journey and how it is to be a woman in the world of physics today during a discussion round with P.E.Mary K Gaillard and the audience. The discussion round will be moderated by Geneviève Guinot, the CERN Diversity Programme Leader. Coffee will be served at 3:30pm. Th...

  17. Footprints, Imprints: Seeing Environmentalist and Buddhist Marie Byles as an Eastern Australian

    Directory of Open Access Journals (Sweden)

    Allison Jane Cadzow

    2007-01-01

    Full Text Available This paper looks at the Australian author, traveller, conservationist and Buddhist Marie Byles (1900-1979 as “eastern” and Australian at once. It investigates the influence of Buddhist spirituality and travel on her approach to the environment and explores some possibilities arising from looking at her work as part of a broader transnational humanitarian and intellectual identification, moving beyond ethnicity based boundaries. Thinking about eastern Australian identities can encourage consideration of Australia in Asia, Australia as Asian, connections across seas, and links and differences within Australia. The paper explores Marie Byles as an eastern Australian by considering her travel in Sydney and the region (in Australia, China, Vietnam, India and Burma from the 1930s to the 1960s, the design and use of her home as a hub for early Buddhist meetings, her publication of texts discussing Eastern philosophy, and her environmental activism. Throughout the discussion Byles’s understanding of power relations, derived from an entwining of feminist and socialist ideas, a pacifist and Buddhist/spiritualist revaluation of environments emerges. From these influences she provided challenges to her fellow walkers, environmentalists, and society at large to rethink relationships with nature and each other, insights that have yet to be adequately explored and recognised.

  18. Reliability of the CMT neuropathy score (second version) in Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Murphy, Sinéad M

    2011-09-01

    The Charcot-Marie-Tooth neuropathy score (CMTNS) is a reliable and valid composite score comprising symptoms, signs, and neurophysiological tests, which has been used in natural history studies of CMT1A and CMT1X and as an outcome measure in treatment trials of CMT1A. Following an international workshop on outcome measures in Charcot-Marie-Tooth disease (CMT), the CMTNS was modified to attempt to reduce floor and ceiling effects and to standardize patient assessment, aiming to improve its sensitivity for detecting change over time and the effect of an intervention. After agreeing on the modifications made to the CMTNS (CMTNS2), three examiners evaluated 16 patients to determine inter-rater reliability; one examiner evaluated 18 patients twice within 8 weeks to determine intra-rater reliability. Three examiners evaluated 63 patients using the CMTNS and the CMTNS2 to determine how the modifications altered scoring. For inter- and intra-rater reliability, intra-class correlation coefficients (ICCs) were ≥0.96 for the CMT symptom score and the CMT examination score. There were small but significant differences in some of the individual components of the CMTNS compared with the CMTNS2, mainly in the components that had been modified the most. A longitudinal study is in progress to determine whether the CMTNS2 is more sensitive than the CMTNS for detecting change over time.

  19. In search of the Boston Strangler: genetic evidence from the exhumation of Mary Sullivan.

    Science.gov (United States)

    Foran, David R; Starrs, James E

    2004-01-01

    The Boston Strangler was one of the United States' most notorious serial killers, raping and strangling with decorative ligatures thirteen woman in Boston during the early 1960s. Albert DeSalvo, never a suspect in the slayings, confessed in prison (where he was later murdered) to being the Boston Strangler, and the investigation largely ended. Mary Sullivan was the last victim of the Boston Strangler, found sexually assaulted and strangled in her Boston apartment in 1964. Recently, a team of forensic scientists undertook the exhumation and subsequent scientific analysis of Mary Sullivan's remains, in hope of finding consistencies or inconsistencies between DeSalvo's confessed description of the murder and any evidence left behind. Included in these analyses was extensive DNA testing of all UV fluorescent material associated with the body. The large majority of results were negative, however, fluorescent material located on the underwear and entwined in her pubic hair generated two human mitochondrial DNA sequences. Neither of these matched the victim nor members of the forensic team who worked on the evidence. Most importantly, neither DNA sequence could have originated from Albert DeSalvo.

  20. Monological Drama to Reshape the Northern Irish Identity: A Night in November by Marie Jones

    Directory of Open Access Journals (Sweden)

    Virginie Privas

    2010-03-01

    Full Text Available In this contemporary one-man theatre play, Marie Jones’s character, Kenneth McCallister, is prompted to break free from the prejudices in and against Northern Ireland. Indeed, the playwright aims at finding new ways to deconstruct the preconceived idea that there are two different identities in Northern Ireland closely linked to the division between two religious communities. Instead, she seeks connections, even with the Irish who migrated (the diasporic dimension, though, is not to be discussed within this paper. The author explores this possibility through the psychological evolution of a Northern Irish Protestant who comes to lack references in terms of identity. On stage, he recalls the events that launched him on a quest to redefine his identity, an identity in which his religious denomination is taken into account but is not the only community marker. Marie Jones eventually offers an insight into what being and feeling Irish means for someone who has always lived as a Protestant in Northern Ireland. Monologue and the notion of “frontiers” (be they social, political, geographical, historical or theatrical that emerge only to be destroyed, are some of the theatrical devices she resorts to in order to voice her aim in  this experimental play which ultimately proposes to reshape the contours of Northern Irish drama about the Troubles.

  1. Community stability within the St. Marys River fish community: Evidence from trawl surveys

    Science.gov (United States)

    Schaeffer, Jeffrey S.; Bowen, Anjanette K.; Fielder, David G.

    2017-01-01

    A trawl survey was conducted in the Saint Marys River during 2010–2011 and we compared our results to a prior trawl survey conducted during 1979–1983 to look for long-term changes in the fish community, especially in terms of changes induced by invasive species. We found no substantive temporal differences in fish density, fish biomass, or fish diversity; lower trawl biomass during 2010–2011 was likely a result of day versus night trawling. The Saint Marys River remains a center of high fish diversity, invasive species remain rare, and the system continues to exhibit overall long-term stability. Trawling captured a wide range of fish species, but was likely not an effective stock assessment tool for managed game fish because catch rates were low or variable for all game species except yellow perch. Trawling appeared to be an effective tool for sampling connecting channel diversity, especially when large numbers of individuals are needed for directed studies, but annual sampling would be needed to use data to assess recruitment.

  2. Mariátegui y la constitución de un socialismo latinoamericano

    Directory of Open Access Journals (Sweden)

    César Ruiz Sanjuán

    2015-01-01

    Full Text Available En el presente artículo se analizan los aspectos fundamentales de la concepción socialista de Mariátegui, poniendo de manifiesto sus planteamientos historicistas y voluntaristas frente al economicismo y al determinismo dominantes en la tradición marxista, así como su reformulación del materialismo histórico como método de interpretación no sólo de las sociedades capitalistas desarrolladas, sino también de las sociedades coloniales en las que el capitalismo se encuentra combinado con elementos supervivientes de formaciones sociales anteriores. Se aborda asimismo la comprensión de Mariátegui del partido político como forma de articulación de las relaciones de fuerza de las clases subalternas, que debe emerger del proceso de formación de una voluntad colectiva entre las mismas. Finalmente se examina el modo en que integra en su concepción socialista la cuestión de indigenismo para plantear una forma de transición hacia un socialismo específicamente latinoamericano.

  3. Implementasi Modulasi dan Demodulasi M-ary QAM pada DSK TMS320C6416T

    Directory of Open Access Journals (Sweden)

    Angga Yuda Prasetya

    2013-03-01

    Full Text Available Salah satu jenis modulasi digital yang sering digunakan adalah QAM (Quadrature Amplitude Modulation. Modulator dan demodulator M-ary QAM dapat diprogram dengan menggunakan DSP processor. DSK TMS320C6416T adalah suatu board/hardware untuk memproses sinyal yang termasuk dalam keluarga besar processor TMS320 produksi Texas Instrument, bekerja pada frekuensi 0-96 kHz yang merupakan standar dalam sistem telekomunikasi. Tujuannya yaitu melakukan implementasi modulasi dan demodulasi M-ary QAM secara real ke dalam DSP Starter Kit TMS320C6416T. Terdapat empat implementasi sistem yaitu sistem dengan input bernoulli binary generator, input pulse generator, sinyal input dari function generator melalui port Line-In dan input suara melalui port Mic-In. Pengujian dilakukan untuk mengetahui kinerja DSK TMS320C6416T yang ditampilkan dalam bentuk grafik Bit Error Rate terhadap variasi nilai Eb/N0 dilakukan dengan mengirimkan 100.000 bit. Kinerja terbaik terdapat pada implementasi menggunakan sistem QAM dengan nilai BER mencapai 1.00E-05 pada nilai Eb/N0≥11dB. Sedangkan kinerja terburuk pada semua sistem dengan input dari function generator dengan nilai BER yang tidak mencapai 1.00E-05 dibandingkan dengan sistem yang telah dirancang.

  4. Mapping Femininity as Self-reflection Strategy in Lady Mary Wortley Montagu’s Travel Letters

    Directory of Open Access Journals (Sweden)

    Amelia Precup

    2017-07-01

    Full Text Available The present paper participates in the discussion about the differences between masculine and feminine modes of travel in terms of interests, perception, and representation, by exploring the Letters of the Right Honourable Lady M--y W--y M--e Written during Her Travels in Europe, Asia and Africa, by Lady Mary Wortley Montagu. As a traveller, Lady Mary engaged in the contemplation of cultural landscapes: she attempted to understand the social logic of the communities she met and to assess the cultural distance between the English society and the local customs of the countries she visited. Within this large social and cultural framework, the focus of her keen spirit of observation is represented, in many of her letters, by gender dynamics and the status of women, thus allowing a feminine configuration of the map of continental Europe and the Ottoman Empire and a comparative understanding of femininity and expected feminine behaviour. Therefore, the contention of this paper is that, in Lady Mary’s letters, the female-traveller’s gaze ends in meditation and self-contemplation, and functions as a means of comparing and reassessing female identity.

  5. Marie Uguay et Saint-Denys Garneau, au bord du vide

    Directory of Open Access Journals (Sweden)

    Mylène Durand

    2010-04-01

    Full Text Available « Marie Uguay et Saint-Denys Garneau : au bord du vide » est un texte qui rapproche les oeuvres de ces deux poètes, qui ont plusieurs points en commun. Toutes les deux dénotent une conscience de la mort, une vision lucide de celle-ci. Leurs oeuvres poétiques montrent que leurs sujets lyriques se situent dans une espèce d’entre-deux, d’excroissance du temps, un seuil qu’ils cherchent à nommer. Est-ce « l’Outre-vie » d’Uguay ? « La faction » de Saint-Denys Garneau ? Les sujets explorent un espace-temps particulier, un lieu qui rappelle les limbes, la mort et la vie tout à la fois. Un monde onirique, de rêves ou de cauchemars. Les sujets se situent au bord de limites apparemment infranchissables, mais au-delà desquelles semble se trouver la vie. Prisonniers de ces espaces intérimaires, ils sont seuls, blessés, comme d’un côté d’une fenêtre fermée, donnant à voir sur un monde inaccessible. Pourtant, ils désirent traverser tous ces seuils, physiques et métaphoriques, pour aller vers la vie. Traverser ces «limites sanglantes», comme l’écrit Marie Uguay. En effet, les sujets sont blessés, fragmentés, et malgré tout ils cherchent leurs chemins, avancent pour combattre l’enfermement, l’immobilité. L’espoir advient par l’écriture, la poésie plus particulièrement, qui permet tout, qui trace un chemin, des ponts; ouvre des voies vers la lumière, la vie.This is a comparative analysis of the works of two Quebecois poets, Saint-Denys Garneau and Marie Uguay who have many common points.  Both express a conscience and a lucid vision of death. Their poetic works show that their lyric subjects are situated in a sort of “in-between”, an excrescence of time, a threshold they are trying to name. Is it what Marie Uguay calls “Outre-vie” or the “faction” of Saint-Denys? The subjects explore a particular space-time, a place that is reminiscent of limbo, life and death at the same time. The

  6. The light of the word in Ljubica Marić's music

    Directory of Open Access Journals (Sweden)

    Makević Zorica

    2009-01-01

    Full Text Available Ljubica Marić's music provides manifold encouragements for consideration in the light of the Logos, according to the teaching exposed in the prologue of the Gospel by St. John. It speaks of the essential inconceivability of time and life, which have their cause in God and His Logos. Seeing through and praising 'the logos of things' guide all its aspects: the tone reveals itself as a vibration, as the energy of lasting and existing, as the beginning of every time and motion; the sonority of different instrumental media is freely expressed and mutually determined in co-action with specific musical and contextual moments; the rhythm evades every regularity and mechanicalness, by which both single duration's and the whole metro-rhythmic course gain a vivid expression. The entire shape of the work is also taken from the reality of psychological and historical time, from its unreductable dynamics, being always in a vivid connection with the space, origin and tradition. The respect for 'the truth of things', the awe before the mystery of time and existence, which call upon the very principle of life in the divine Logos are obvious in everything. Designation of man as a being of light and reason created in the image of God to be the likeness of His being, is expressed in Ljubica Marić's music by the measure of human pulse taken as the basic tempo of her entire opus. Ljubica Marić expressed her consciousness of the reason as a special gift to the man by extremely careful treatment of the words - its meanings, melodies, rhythms, which she always considered the very source of music. The relation between the word and the voice - its sonorous body - is shown in the cantata Songs of Space (1956 as a mystery of the encounter of the Logos and the matter. In relation to her earlier works, this one is a marked breakthrough of the composer's authentic 'voice', which will find its full identity only after receiving the divine Word, symbolized by the melodies of

  7. Interpretation of the icon of Three-handed Virgin Mary of the St. Trinity church in Karan

    Directory of Open Access Journals (Sweden)

    Andrejić Živojin R.

    2016-01-01

    Full Text Available In the church devoted to Presentation of Virgin Mary in Karan there is a monumental fresco icon preserved until today representing Three-handed Virgin Mary, the one of a kind in Byzantine Orthodox style. This icon can be a good model for reconstructing the icon of the same name in the church devoted to Three-handed Virgin Mary in Skoplje in which her cult was established as late as in1204 and renewed by the Serbian king Milutin in 1300. The nun in the deep bow showed in the painting by the legs of Three-handed Virgin Mary in White Church in Karan is the patron of the painting located in a niche formed in a subsequently partitioned south arcade of the iconostatis about the year 1354. The painting of the Three-handed Virgin Mary is related to the fact that the church in Karan was later dedicated to her and obviously connected to an important event during the reign of emperor Dusan. It can also be speculated that it was because of making the church of Three-handed Virgin Mary the seat of the Skopje diocese and its raising to the rank of metropolis of the first degree by emperor Dusan in 1346, presumably on June 28. The church could have memorised a major event related to emperor Dusan and his father, possibly on June 28, 1355 when he successfully ended the war against Hungarian king Ludwig I. There is also a possibility that it was devoted to the day when the daughter of prefect Brian was made a nun in the monastery in Karan in which she would spend the rest of her life and be buried as well, according to her own will and intention. Revealing the tomb in front of Three-handed Virgin Mary confirms the funerary purpose of this fresco icon. The painting of the Virgin Mary's third hand was made according to the universal understanding of the Son by the Mother 'You are my other (left hand'. The three-handedness of Virgin Mary has its analogy in the three-headed representations of archangels and Christ in the Eastern-orthodox areas as a way of giving

  8. Urbanistid ja keskkonnaeksperdid: iga muudatuse eest Reidi tee projektis oleme pidanud võitlema / Helen Sooväli-Sepping, Kristi Grišakov, Mari Jüssi ; intervjueerinud Mari Peegel ; kommenteerinud Taavi Aas

    Index Scriptorium Estoniae

    Sooväli-Sepping, Helen, 1974-

    2016-01-01

    TLÜ keskkonnakorralduse professor ja linnakorralduse õppekava juht Helen Sooväli-Sepping, TTÜ maastikuarhitektuuri õppekava juht ja linnaplaneerija-urbanist Kristi Grišakov ning Stockholmi keskkonnainstituudi Tallinna keskuse liikuvus- ja keskkonnaekspert Mari Jüssi kinnitavad, et Reidi tee projekt ei ole endiselt inimsõbralik

  9. Quantitative measurement of duplicated DNA as a diagnostic test for Charcot-Marie-Tooth disease type 1a

    NARCIS (Netherlands)

    Hensels, G. W.; Janssen, E. A.; Hoogendijk, J. E.; Valentijn, L. J.; Baas, F.; Bolhuis, P. A.

    1993-01-01

    Charcot-Marie-Tooth disease type 1 (CMT1) is a hereditary motor and sensory neuropathy. The autosomal dominant subtype is often linked with a large duplication on chromosome 17p11.2. The gene encoding the peripheral myelin protein PMP 22 (the critical gene in this subtype of CMT1) is located within

  10. Kuis saada läbi Siirita? / Mari-Ann Kelam, Erika Salumäe, Sirje Endre

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2001-01-01

    Riigikogu uude juhatusse ei kuulu ühtegi naist : Keskerakond valis Siiri Oviiri asemele Riigikogu aseesimehe kohale Peeter Kreitzbergi. Naiste osalemisvõimalust poliitikas kommenteerivad Riigikogu naisliikmed Mari-Ann Kelam, Erika Salumäe, Sirje Endre, Jaana Padrik, Viive Rosenberg, Mai Treial, Ivi Eenmaa, Liis Klaar, Liia Hänni, Laine Tarvis

  11. PMP22 related neuropathies: Charcot-Marie-Tooth disease type 1A and Hereditary Neuropathy with liability to Pressure Palsies

    NARCIS (Netherlands)

    van Paassen, Barbara W.; van der Kooi, Anneke J.; van Spaendonck-Zwarts, Karin Y.; Verhamme, Camiel; Baas, Frank; de Visser, Marianne

    2014-01-01

    PMP22 related neuropathies comprise (1) PMP22 duplications leading to Charcot-Marie-Tooth disease type 1A (CMT1A), (2) PMP22 deletions, leading to Hereditary Neuropathy with liability to Pressure Palsies (HNPP), and (3) PMP22 point mutations, causing both phenotypes. Overall prevalence of CMT is

  12. 76 FR 31839 - Safety Zones; Annual Events Requiring Safety Zones in the Captain of the Port Sault Sainte Marie...

    Science.gov (United States)

    2011-06-02

    ... water areas within the Sector Sault Sainte Marie Captain of the Port zone. These safety zones are necessary to protect spectators, participants, and vessels from the hazards associated with various maritime... within any particular area are expected to be minimal. Under certain conditions, moreover, vessels may...

  13. 76 FR 38297 - Safety Zone; Marine Events Requiring Safety Zones in the Captain of the Port Sault Sainte Marie Zone

    Science.gov (United States)

    2011-06-30

    ... areas within the Sector Sault Sainte Marie Captain of the Port zone. These safety zones are necessary to protect spectators, participants, and vessels from the hazards associated with various maritime events... would inhibit the Coast Guard's ability to protect the public from the hazards associated with various...

  14. 76 FR 21677 - Safety Zones; Annual Events Requiring Safety Zones in the Captain of the Port Sault Sainte Marie...

    Science.gov (United States)

    2011-04-18

    ... will restrict vessels from certain portions of water areas within the Sector Sault Ste Marie Captain of the Port zone, as defined by our regulations. These proposed safety zones are necessary to protect spectators, participants, and vessels from the hazards associated with various maritime events. DATES...

  15. Marie Underi luule : mõnest tõlkeprobleemist / Ilse Lehiste ; inglise k. tlk. Ene-Reet Soovik

    Index Scriptorium Estoniae

    Lehiste, Ilse, 1922-2010

    2000-01-01

    Orig.: Marie Under's poetry: some problems of translation. Varem ilmunud: Lituanus, 1983, nr. 3. Kaasautor: Rimvydas Shilbajoris. M. Underi luuletuse "Täiskuu" tekst eesti k., tõlge inglise keelde (tlk. I. Lehiste) ja reaalune tõlge inglise keelde, lk. 256-260

  16. Ühendused ja lühised Kärdla diiselelektrijaamas / Maris Sander, Margit Tõnson, Kairi Prints

    Index Scriptorium Estoniae

    Sander, Maris

    2009-01-01

    Siret Paju asutas DRAKAdeemia (Draamakirjanike akadeemia). Hea Energia Festivalil Hiiumaal Kärdla elektrijaamas mängiti erinevatest teatritest näitlejatega akadeemikute esimest lavastust "Ei teki ega kao" (autorid Kerli Adov, Jaan Aps, Liis Lukk, Hiri Müüripeal, Siim Nurklik, Kaur Riismaa). Maris Sander, Margit Tõnson ja Kairi Prints arvustavad

  17. Spine deformities in Charcot-Marie-Tooth 4C caused by SH3TC2 gene mutations.

    NARCIS (Netherlands)

    Azzedine, H.; Ravise, N.; Verny, C.; Gabreëls-Festen, A.A.W.M.; Lammens, M.M.Y.; Grid, D.; Vallat, J.M.; Durosier, G.; Senderek, J.; Nouioua, S.; Hamadouche, T.; Bouhouche, A.; Guilbot, A.; Stendel, C.; Ruberg, M.; Brice, A.; Birouk, N.; Dubourg, O.; Tazir, M.; LeGuern, E.

    2006-01-01

    BACKGROUND: Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited peripheral motor and sensory neuropathies with several modes of inheritance: autosomal dominant, X-linked, and autosomal recessive (AR) CMT. A locus responsible for the demyelinating form of ARCMT was assigned to the

  18. THE STUDY OF PRICING IN THE SPHERE OF EDUCATIONAL SERVICES (ON THE EXAMPLE OF THE REPUBLIC OF MARI EL

    Directory of Open Access Journals (Sweden)

    N. G. Ackoraeva

    2010-01-01

    Full Text Available The summary: the basic features of pricing of educational services of higher educational institutions Are considered. Research of the market of educational services of republic of Mary El is carried out. Recommendations about formation of price strategy depending on influence of the big spectrum of external factors are offered.

  19. Zora Neale Hurston's "Their Eyes Were Watching God" and the Influence of Jens Peter Jacobsen's "Marie Grubbe."

    Science.gov (United States)

    Woodson, Jon

    1992-01-01

    Argues that Harlem Renaissance literary figure, Zora Neale Hurston, may have written her novel of a three-times married woman, "Their Eyes Were Watching God," under the influence of and in response to "Marie Grubbe," a novel by a nineteenth-century Danish man. (JB)

  20. Aerobic anti-gravity exercise in patients with Charcot-Marie-Tooth disease types 1A and X

    DEFF Research Database (Denmark)

    Knak, Kirsten L; Andersen, Linda K; Vissing, John

    2017-01-01

    Background: Charcot-Marie-Tooth (CMT) disease is a hereditary neuropathy associated with impaired walking capacity. Some patients are too weak in the lower extremity muscles to walk at gravity with sufficient intensity or duration to gain benefit. Aim: The aim was to investigate the effect of aer...

  1. Sisemine vabadus määrab identiteedi / Marie-Jo LaFontaine ; interv. Reet Varblane

    Index Scriptorium Estoniae

    LaFontaine, Marie-Jo

    2001-01-01

    Intervjuu belgia kunstniku Marie-Jo LaFontaine'iga 25. VII Rakveres. KanaNaha raames eksponeeritud M.-J. LaFontaine'i näitusest "Identiteedi ruum", tema fotodest lastest, kunstiturust Eestis ja Belgias, Belgia pankade kunstikogudest jm.

  2. Deaf-Accessibility for Spoonies: Lessons from Touring "Eve and Mary Are Having Coffee" While Chronically Ill

    Science.gov (United States)

    Barokka (Okka), Khairani

    2017-01-01

    This article presents lessons from touring a show on pain with limited resources and in chronic pain. In 2014, I toured solo deaf-accessible poetry/art show "Eve and Mary Are Having Coffee" in various forms in the UK, Austria, and India. As an Indonesian woman with then-extreme chronic pain and fatigue, herein are lessons learned from…

  3. Charcot-Marie-Tooth disease type 1A: morphological phenotype of the 17p duplication versus PMP22 point mutations

    NARCIS (Netherlands)

    Gabreëls-Festen, A. A.; Bolhuis, P. A.; Hoogendijk, J. E.; Valentijn, L. J.; Eshuis, E. J.; Gabreëls, F. J.

    1995-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) or hereditary motor and sensory neuropathy type Ia (HMSN type Ia) is an autosomal dominant demyelinating polyneuropathy, which may result from duplications as large as 1.5 Mb on chromosome 17p 11.2-p12 encompassing the gene for the peripheral myelin

  4. The first de novo mutation of the connexin 32 gene associated with X linked Charcot-Marie-Tooth disease

    NARCIS (Netherlands)

    Meggouh, F.; Benomar, A.; Rouger, H.; Tardieu, S.; Birouk, N.; Tassin, J.; Barhoumi, C.; Yahyaoui, M.; Chkili, T.; Brice, A.; LeGuern, E.

    1998-01-01

    X linked Charcot-Marie-Tooth disease (CMTX) is a hereditary motor and sensory neuropathy caused by mutations in the connexin 32 gene (Cx32). Using the SSCP technique and direct sequencing of PCR amplified genomic DNA fragments of the Cx32 gene from a Moroccan patient and her relatives, we identified

  5. Metsanduse kommunikatsioonile tuleb kasuks inimeste metsa toomine / Mari-Liis Kitter, Toomas Kelt, Regina Hansen ; intervjueerinud Kertu Kärk

    Index Scriptorium Estoniae

    Kitter, Mari-Liis

    2014-01-01

    Metsanduse kommunikatsiooni suurimatest väljakutsetest ja saavutustest räägivad vestlusringis RMK kommunikatsioonijuht Mari-Liis Kitter, Eesti Metsaseltsi kommunikatsioonijuht Toomas Kelt ja Erametsakeskuse, Eesti Metsa- ja Puidutööstuse Liidu ja Eesti Erametsaliidu kommunikatsioonijuht Regina Hansen

  6. Flood-inundation maps for the St. Marys River at Fort Wayne, Indiana

    Science.gov (United States)

    Menke, Chad D.; Kim, Moon H.; Fowler, Kathleen K.

    2012-01-01

    Digital flood-inundation maps for a 9-mile reach of the St. Marys River that extends from South Anthony Boulevard to Main Street at Fort Wayne, Indiana, were created by the U.S. Geological Survey (USGS) in cooperation with the City of Fort Wayne. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site, depict estimates of the areal extent of flooding corresponding to selected water levels (stages) at the USGS streamgage 04182000 St. Marys River near Fort Wayne, Ind. Current conditions at the USGS streamgages in Indiana may be obtained from the National Water Information System: Web Interface. In addition, the information has been provided to the National Weather Service (NWS) for incorporation into their Advanced Hydrologic Prediction Service (AHPS) flood warning system. The NWS forecasts flood hydrographs at many places that are often collocated at USGS streamgages. That forecasted peak-stage information, also available on the Internet, may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, water-surface profiles were simulated for the stream reach by means of a hydraulic one-dimensional step-backwater model. The model was calibrated using the most current stage-discharge relation at the USGS streamgage 04182000 St. Marys River near Fort Wayne, Ind. The hydraulic model was then used to simulate 11 water-surface profiles for flood stages at 1-ft intervals referenced to the streamgage datum and ranging from bankfull to approximately the highest recorded water level at the streamgage. The simulated water-surface profiles were then combined with a geographic information system digital elevation model (derived from Light Detection and Ranging (LiDAR) data) in order to delineate the area flooded at each water level. A flood inundation map was generated for each water-surface profile stage (11 maps in all) so that for any given flood stage users will be

  7. Mariátegui entre dois mundos: Visões do comunitarismo indígena andino

    Directory of Open Access Journals (Sweden)

    Cristhian Teófilo da Silva

    2014-12-01

    Full Text Available Resumo  Este artigo visa demonstrar que a presença da herança andina no projeto de socialismo “indo-americano” de Mariátegui gerou uma tensão epistemológica original e crítica do pensamento social marxista na América Latina. A partir desta releitura da perspectiva mariateguiana apoiada em duas vertentes, indigenista peruana e marxista europeia, o presente artigo afirma a importância dos estudos sobre o indigenismo para a compreensão dos limites do socialismo de orientação marxista no Peru. O artigo será concluído ressaltando a importância do socialismo indo-americano de Mariátegui para a “descoberta” da constituição híbrida do modo de produção peruano.  Palavras-chave  Indigenismo; marxismo; Peru; José Carlos Mariátegui  --- Resumen  Este artículo tiene como objetivo demostrar que la presencia de la herencia andina en el diseño del socialismo "indoamericano" de Mariátegui ha generado una crítica epistemológica original del pensamiento social marxista en América Latina. De este recuento la perspectiva de Mariátegui apoyada en dos frentes, indigenista peruana y marxista europea, este artículo defiende la importancia de los estudios sobre el indigenismo para la comprensión de los límites del socialismo marxista en el Perú. El artículo concluirá destacando la importancia del socialismo indo-americano de Mariátegui en el "descubrimiento" de la constitución híbrida del modo de producción peruana.  Palabras clave  Indigenismo; marxismo; Perú; José Carlos Mariátegui --- Abstract This article aims to demonstrate that the presence of the Andean heritage in Mariátegui's "Indo-American" socialist project generated a new and critical epistemological tension of the Marxist social thinking in Latin America. From this mariateguian retelling, which is established in two ways, Peruvian indigenous and European Marxist, this article maintains the importance of studies on the indigenous movement to understand

  8. Seca Jean-Marie, Dir., Musiques populaires underground et représentations du politique

    Directory of Open Access Journals (Sweden)

    Régis Malige

    2011-03-01

    Full Text Available Mondialisées, urbanisées et massifiées, les sociétés postmodernes veulent com­prendre le sens des mutations permanentes qu’elles rencontrent. Dans le contexte ano­mique du moment, les musiques populaires underground, d’inspiration anglaise et américaine (jazz, punk, rap, techno, metal, rock…, proposent des éléments de réponse et développent un système de représentations questionnant l’action publique. L’ouvrage, coordonné par Jean-Marie Seca et auquel ont collaboré une bonne quin­zaine de ch...

  9. Report for MaRIE Drivers Workshop on needs for energetic material's studies.

    Energy Technology Data Exchange (ETDEWEB)

    Specht, Paul Elliott [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-01-01

    Energetic materials (i.e. explosives, propellants, and pyrotechnics) have complex mesoscale features that influence their dynamic response. Direct measurement of the complex mechanical, thermal, and chemical response of energetic materials is critical for improving computational models and enabling predictive capabilities. Many of the physical phenomena of interest in energetic materials cover time and length scales spanning several orders of magnitude. Examples include chemical interactions in the reaction zone, the distribution and evolution of temperature fields, mesoscale deformation in heterogeneous systems, and phase transitions. This is particularly true for spontaneous phenomena, like thermal cook-off. The ability for MaRIE to capture multiple length scales and stochastic phenomena can significantly advance our understanding of energetic materials and yield more realistic, predictive models.

  10. “On the brink of the absolutely forbidden”: In Conversation with Mary Morrissy

    Directory of Open Access Journals (Sweden)

    Loredana Salis

    2016-06-01

    Full Text Available Mary Morrissy (Dublin, 1957 belongs to the generation of womenwriters excluded from the Field Day Anthology in the 1990s, only tobe included in a dedicated volume in 2003. By then she had becomea distinguished literary voice in Ireland (having published a collectionof short stories, and two novels. After The Rising of Bella Casey (2013,Morrissy returned to the short story in the form of an adaptation ofJoyce’s “An Encounter” (2014, and a collection of short stories entitledProsperity Drive (2016. Situated where history, biography andfiction intersect, her works deal with Ireland’s recent cultural developmentsand situations of marginality risking social exclusion, genderinequality, an indelible past and the dominance of religion. Standing“on the brink of the absolutely forbidden”, her protagonists, like herwriting, yearn to break taboos and

  11. PERBINCANGAN MENGENAI HUKUMAN MATI TERKAIT KASUS BALI NINE DAN MARY JANE DALAM SITUS JEJARING SOSIAL TWITTER

    Directory of Open Access Journals (Sweden)

    Jimi Narotama Mahameruaji

    2016-06-01

    Full Text Available Twitter telah menjadi alat atau media komunikasi yang sangat populer diantara para pengguna Internet. Melalui Twitter, penggunanya dapat berbagi cerita hidup mereka sehari-hari, melakukan perbincangan dengan pengguna lain dan juga mengekspresikan pendapat mereka. Twitter juga dapat dilihat sebagai sebuah wadah untuk melakukan perbincangan politik dan isu-isu publik. Oleh karena itu, peran Twitter terkait partisipasi publik, kampanye, dan pembentukan opini publik kini semakin diperhitungkan (Jungherr, 2015. Fokus penelitian ini tentang perbincangan para pengguna Twitter di Indonesia mengenai peristiwa hukuman mati kasus narkoba Bali Nine dan Mary Jane. Penelitian ini bertujuan untuk mengetahui apa ragam perbincangan yang terjadi di antara para pengguna Twitter Indonesia terkait kasus hukuman mati tersebut, apa argumen yang muncul terkait penolakan maupun dukungan terhadap isu hukuman mati, dan juga siapa saja Twitter Influencer yang berperan dalam isu ini.   DOI: 10.24198/jkk.vol4n1.5

  12. Standards of radium-226: from Marie Curie to the International Committee for Radionuclide Metrology.

    Science.gov (United States)

    Coursey, B M; Collé, R; Coursey, J S

    2002-01-01

    In the early part of the 20th century, the pioneers of radioactivity research, led by Marie Curie, Ernest Rutherford and Stefan Meyer, formed a Commission internationale des étalons de radium. The Commission made arrangements for the preparation and intercomparisons of the international standards of radium, which were identified as the Paris standard and the Vienna standard. Otto Hönigschmid from Vienna prepared a first set of international secondary standards in 1912 and a second set in 1934. In both instances, these secondary standards were compared by gamma-ray measurements with the Paris and Vienna standards. The usage of these international standards of radium in the 20th century is described.

  13. [Mary Shelley's Frankenstein and Bram Stoker's Dracula: gender and science in literature].

    Science.gov (United States)

    de La Rocque, L

    2001-01-01

    Throughout the ages, literary works have expressed fears and expectations generated by scientific discoveries and have portrayed images and myths about science itself. Several parameters can contribute to these representations of science, including the culture and social class to which the authors of these works belong. We also cannot deny the influence of gender, as due to the fact that the male sphere of action dominates science, male or female authoring can determine a peculiar characterization of the scientific world. In the present work, through a comparative analysis of two important literary works from the 19th century, Frankenstein, by Mary Shelley, and Dracula, by Bram Stoker, the issues concerning the view of science and their relation to gender are highlighted. While Shelley, as a woman, apart from the scientific world, reveals in Frankenstein all her distrust about it, Stoker, the model of a Victorian man, expresses in Dracula his total trust in science.

  14. Genetic dysfunction of MT-ATP6 causes axonal Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Pitceathly, Robert D S

    2012-09-11

    Charcot-Marie-Tooth (CMT) disease is the most common inherited neuromuscular disorder, affecting 1 in 2,500 individuals. Mitochondrial DNA (mtDNA) mutations are not generally considered within the differential diagnosis of patients with uncomplicated inherited neuropathy, despite the essential requirement of ATP for axonal function. We identified the mtDNA mutation m.9185T>C in MT-ATP6, encoding the ATP6 subunit of the mitochondrial ATP synthase (OXPHOS complex V), at homoplasmic levels in a family with mitochondrial disease in whom a severe motor axonal neuropathy was a striking feature. This led us to hypothesize that mutations in the 2 mtDNA complex V subunit encoding genes, MT-ATP6 and MT-ATP8, might be an unrecognized cause of isolated axonal CMT and distal hereditary motor neuropathy (dHMN).

  15. Next-generation sequencing and genetic diagnosis of Charcot-Marie-Tooth disease

    Directory of Open Access Journals (Sweden)

    Ashok Verma

    2014-01-01

    Full Text Available Over 70 different Charcot-Marie-Tooth disease (CMT–associated genes have now been discovered and their number is growing. Conventional genetic testing for all CMT genes is cumbersome, expensive, and impractical in an individual patient. Next-generation sequencing (NGS technology allows cost-effective sequencing of large scale DNA, even entire exome (coding sequences or whole genome and thus, NGS platform can be employed to effectively target a large number or all CMT-related genes for accurate diagnosis. This overview discusses how NGS can be strategically used for genetic diagnosis in patients with CMT or unexplained neuropathy. A comment is made to combine simple clinical and electrophysiological algorithm to assign patients to major CMT subtypes and then employ NGS to screen for all known mutations in the subtype-specific CMT gene panel.

  16. Mis tulemust teie meeleavalduselt ootate? / Liivi Kulli, Jaanus Gross, Mari-Viivian Laht ... [jt.

    Index Scriptorium Estoniae

    2011-01-01

    Küsimusele vastasid Rakvere reaalgümnaasiumi inglise ja saksa keele õpetaja Liivi Kulli, Turba gümnaasiumi arvutiõpetuse õpetaja Jaanus Gross, Kiltsi põhikooli eesti keele ja kirjanduse õpetaja Mari-Viivian Laht, Ruusa kooli ja Mikitamäe põhikooli inglise keele õpetaja Anne Must, Kunda ühisgümnaasiumi klienditeeninduse õpetaja Evely Press, Tõstamaa keskkooli käsitöö- ja kunstiõpetaja, Inger Vahuvee, prantsuse lütseumi kehalise kasvatuse õpetaja Urmas Kokk, Tõnismäe reaalkooli kehalise kasvatuse õpetaja Mihhail Tõrtõšnõi, Ruila põhikooli inglise keele õpetaja Margit Levoll, ametiühingute keskliidu juht Harri Taliga

  17. BER Performance of M-ary FSK Modulation over AWGN and Rayleigh Fading Channels

    Directory of Open Access Journals (Sweden)

    Yazen Saifuldeen Almashhadani

    2017-07-01

    Full Text Available In a mobile communication environment, there is a rising demand of low Bit Error Rate (BER. The channel is not time invariant since the received signal depends on many fast changing factors, and thus it will lead to fading channels. Statistical models are typically used to simulate fading. In this paper, the BER versus Eb/No will simulate the non-faded and faded channels. Using Rayleigh statistical model, the BER of different channel fading types is studied based on time delay spread can have flat fading or frequency selective fading and also based on the Doppler shift can have slow fading or fast fading taking into consideration the M-ary FSK modulation scheme. The overall system is implemented by using MATLAB.

  18. Radioisótopos e sociedade : o legado de Marie Curie 100 anos depois

    OpenAIRE

    André, João P.; Sá, Arsénio Vasconcelos

    2011-01-01

    No ano em que se comemora o centenário da atribuição do Prémio Nobel da Química a Marie Curie e o Ano Internacional da Química, é oportuno recordar e analisar a herança deixada à Humanidade por esta cientista excepcional. Trata-se de um legado que não só revolucionou a ciência como igualmente teve impactos profundos e incontornáveis na sociedade. A aplicação clínica dos radioisótopos, por ela e por Pierre Curie preconizada, constitui uma das armas mais poderosas para o combate ao cancro actua...

  19. Marie-Christine Agosto. Richard Brautigan. Les fleurs de néant.

    Directory of Open Access Journals (Sweden)

    Jean-Bernard Basse

    2006-04-01

    Full Text Available Richard Brautigan, si on lui reconnaît un certain humour, est souvent associé avec condescendance au phénomène hippy et considéré comme un auteur démodé, superficiel. Celui qui écrivait dans Cahier d’un Retour de Troie : « Les mots sont des fleurs de néant » est pourtant l’un de ces écrivains que l’on pourrait qualifier de mineurs essentiels, et seuls ceux qui l’ont peu ou mal lu s’étonneront de ce que Marie-Christine Agosto ait choisi de donner comme sous-titre « Les fleurs de néant » au pet...

  20. [If digital clubbing appears bear Marie-Bamberger disease in mind].

    Science.gov (United States)

    Hartig, I; Matveeva, I; Braun, M G

    2015-10-01

    Secondary hypertrophic osteoarthropathy, also known as Marie-Bamberger disease, occurs in up to 5 % of patients with non-small cell lung cancer (NSCLC). If the syndrome constellation of finger clubbing and bone pain on palpation is recognized early, lung cancer can be diagnosed at an early stage. This article reports the case of a 52-year-old male patient with knee pain, distal edema, watchglass nails and finger clubbing which first appeared in August 2013. Following angiologic, cardiologic and orthopedic consultations radiographs of the hands, feet and lungs were taken. Following the presumptive diagnosis of hypertrophic osteoarthropathy, the patient was referred to a specialist pulmonary clinic where an adenocarcinoma of the lungs was diagnosed.

  1. Simplified Soft-output Demapper Based on a Linear Transformation Technique for M-ary PSK

    Directory of Open Access Journals (Sweden)

    Jianping Li

    2014-10-01

    Full Text Available Combining channel coding with high-order modulation schemes, namely coded modulation (CM, is an efficient digital transmission technology. CM requires the demapper to provide a soft decision bit metric as a part of the inputs to the decoder. This paper proposes an efficient soft- output demapper for M-ary PSK. This novel demodulation algorithm continues to evolve the conventional MAX-Log-MAP algorithm and summarizes the final derivation into a form of matrix multiplication. The Computational complexity for getting one bit soft value of a signal by employing the proposed algorithm remains a constant with the increase of modulation order. Meanwhile, the theoretical analysis and simulation results prove that the novel simplified soft-output demapper can obtain the same performance as MAX-Log-MAP.

  2. Diagnóstico clínico de la enfermedad Charcot-Marie-Tooth

    Directory of Open Access Journals (Sweden)

    Yuselis Pérez Cid

    2014-08-01

    Full Text Available La enfermedad de Charcot-Marie-Tooth es un trastorno polineuropático genéticamente heterogéneo, en la que se han identificado más de 30 genes responsables; sin embargo, el diagnóstico es posible establecerlo sobre las bases de los estudios clínicos y electrofisiológicos. Constituye un reto en la práctica médica de los países del tercer mundo contar con la realización sistemática de estudios genéticos moleculares de las neuropatías hereditarias, por lo que en este trabajo se enfatiza en los estudios clínico-electrofisiológicos para la clasificación de la CMT

  3. Rewriting the Writing Mother in Marie Darrieussecq's Le Bébé

    Directory of Open Access Journals (Sweden)

    Claire Marrone

    2008-01-01

    Full Text Available This article studies the innovative maternal portrait in Marie Darrieussecq's Le Bébé (2002, the autobiographical story of a mother's first nine months with her newborn son. It also examines how Darrieussecq engages in the riveting debate surrounding maternal creativity. On the one hand, Le Bébé is a "success story," one that attests to the victories of the feminist movement. On the other hand, the text examines the new challenges of today's writing mothers. Throughout the work, the "mother as scientist" analyzes her developing child while the nurturing "mom" pens her joys, discoveries, and difficulties. The article concludes that because the researcher is also the mother, and because this marriage of roles in relation to one’s own child is somewhat jarring, Darrieussecq achieves a striking and truly contemporary maternal portrait.

  4. Charcot-Marie-Tooth disease: The development of a diagnostic platform using next generation sequencing

    DEFF Research Database (Denmark)

    Christensen, Rikke; Væth, Signe; Thorsen, Kasper

    Background: Charcot-Marie-Tooth Disease (CMT) is one of the most common inherited neurological diseases. Today, more than 70 CMT related genes are known to cause inherited neuropathy. The diagnostic strategy in most laboratories is based on Sanger-sequencing of few genes. In our patient cohort......, Sanger sequencing of 4 genes have led to a diagnosis in approximately 30% of the patients. Aims: 1) Development of a targeted NGS platform containing 63 genes that currently are found to be associated with CMT. 2) Analysis of the increased diagnostic yield using this platform to analyze 200 CMT samples...... previously analyzed using Sanger sequencing without identification of a disease causing mutation. Materials and Methods: Libraries for 200 patient samples obtained for CMT diagnostics were prepared using Illumina Truseq and target enrichment using SeqCap EZ Choise Library (Nimblegen). The libraries were...

  5. Bernard Maris, Anti-Manuel d'Economie, Bréal, 2003, 359p.

    Directory of Open Access Journals (Sweden)

    Jean Zin

    2004-02-01

    Full Text Available "Il doit être clair au terme de cet Antimanuel que la gratuité et la solidarité font la croissance, l'invention de la richesse malgré la concurrence, essentiellement inefficace". p.349Après l'Antimanuel de philosophie confié à Michel Onfray, les éditions Bréal publient un Antimanuel d'économie par Bernard Maris (l'oncle Bernard de Charlie-Hebdo. En fait, la forme est relativement proche de celle d'un manuel. Ce qui justifie le titre d'Antimanuel, c'est plutôt de dire le contraire de ce que d...

  6. Fully Human and Fully Divine: The Birth of Christ and the Role of Mary

    Directory of Open Access Journals (Sweden)

    Ann Milliken Pederson

    2015-03-01

    Full Text Available The task given to us for this article was to offer theological responses to, “Can modern biology interpret the mystery of the birth of Christ?” by Giuseppe Benagiano and Bruno Dallapiccola. We are female Protestant theologians and respond to the issues from this perspective. The Christian confession of the virgin birth of Jesus (stated within the Apostles and Nicene creeds is a statement of faith that God became incarnate through the power of the Holy Spirit in the flesh of the human Jesus and, likewise, that God continues to become incarnate in our flesh and in the messy details of our lives. The mystery and miracle of the birth of Jesus has much more to do with the incarnation of God in human flesh and in God’s spirit at work in and with Mary, than to do with Mary’s gynecological or parthenogenical mechanisms. The language of mechanism and miracle, in the ways used by the authors, can reduce the mystery and power of the incarnation. Consequently, we would like to offer a theological interpretation of the birth of Jesus and the role of Mary that expresses the mystery and grace of God’s incarnation not only in human nature, but also in all of nature. Our world is God’s home. We cannot comprehend all the ramifications of what is happening in the sciences and technologies of reproduction and development. However, what we do know is that we cannot stop asking questions, seeking answers, and remaining open to being both critical of, and appreciative of, what the sciences are teaching us about being human and creatures of God.

  7. Pé cavo adquirido na doença de Charcot-Marie-Tooth Acquired pes cavus in Charcot-Marie-Tooth disease

    Directory of Open Access Journals (Sweden)

    Daniel Augusto Carvalho Maranho

    2009-01-01

    Full Text Available As neuropatias sensitivomotoras hereditárias, principalmente a doença de Charcot-Marie-Tooth, manifestam-se frequentemente com o aparecimento de pé cavovaro, deformidade caracterizada pela acentuação fixa do arco plantar e inversão do retropé. O diagnóstico da doença de base e a cuidadosa avaliação do paciente fornecem os elementos-chave para decisão do tratamento. O cavo pode situar-se no antepé, retropé ou ser o resultado da associação das duas localizações. Deformidades combinadas, principalmente varismo e garras dos artelhos, devem ser bem avaliadas; as características clínicas como grau das alterações, acometimento da força muscular, flexibilidade e idade são fatores importantes para a decisão da conduta. O tratamento conservador do pé cavovaro por meio de fisioterapia, palmilhas e adaptação nos calçados é reservado ao paciente mais jovem ou casos levemente acometidos. Entretanto, há tendência de agravamento das deformidades devido à característica progressiva da doença neurológica de base. Assim, o tratamento cirúrgico pelas técnicas clássicas é indicado precocemente, sendo importante identificar as alterações primárias, diferenciá-las das secundárias e corrigi-las, se possível. As transferências musculares são usadas no sentido de minimizar o desequilíbrio, estruturas retraídas são seccionadas ou alongadas e osteotomias localizadas devem ser preferíveis às artrodeses, que são reservadas para pés rígidos e muito deformados de pacientes adultos.Hereditary motor and sensory neuropathies, especially Charcot-Marie-Tooth disease, are frequently expressed with an acquired cavusvarus foot which is characterized by a fixed increase of the plantar arch and hindfoot inversion. Diagnosis of the underlying condition achieved through careful patient assessment and local evaluations is the keystone for decision-making about the adequate treatment. The cavus may present as an isolated deformity of

  8. Doença de Charcot-Marie-Tooth: estudo clínico em 45 pacientes Charcot-Marie-Tooth disease: clinical features in 45 cases

    Directory of Open Access Journals (Sweden)

    Marcos R. G. de freitas

    1995-09-01

    Full Text Available A doença de Charcot-Marie-Tooth (CMT é uma das moléstias mais frequentes do sistema nervoso periférico e ocupa o primeiro lugar dentre as afecções neuromusculares hereditárias. Estudamos 45 pacientes com doença de CMT atendidos no Hospital Universitário Antônio Pedro da Universidade Federal Fluminense. Foram classificados de acordo com a neurocondução em: tipo I (desmielinizante, 11 casos; e tipo II (anoxal, 34 casos. Vinte e três tinham herança autossômica dominante, 7 casos eram do tipo autossômico recessivo e 15 eram esporádicos. A maioria teve o início dos sintomas na 1ª ou 2ª décadas. Todos tiveram paresia distal dos membros inferiores. Nos membros superiores a paresia foi vista em 38,2%. A amiotrofia distal ocorreu em 80% nos membros inferiores e em 50% nos superiores. A arreflexia patelar e aquiliana foi elevada. Abolição dos reflexos profundos nos membros superiores ocorreu em 28%. As alterações sensitivas limitaram-se a discreta hipoestesia nos membros inferiores. Em 7 enfermos encontramos hipertrofia dos troncos nervosos. Os pés cavos e a escoliose foram vistos em 21 casos e 7 casos respectivamente. Tremor nas mãos foi encontrado em 6 pacientes. Outros sinais mais raros, como oligofrenia e atrofia óptica, foram vistos excepcionalmente. A evolução da doença foi quase sempre benigna. Somente 7 casos evoluíram rapidamente.Charcot-Marie-Tooth (CMT disease is the commonest inherited peripheral neuropathy. The clinical study of 45 patients with CMT is presented. They were derived from Antonio Pedro Hospital of Universidade Federal Fluminense in Niteroi, RJ, Brazil. Such patients could be divided by the motor conduction velocity in two types: a demyelinating form or type I (11 cases and an axonal form or type II (34 cases. The disease was inherited as an autosomal dominant trait in 23 patients and as an autosomal recessive trait in 7 cases. In 15 patients the disorder was sporadic. The age of onset was in most

  9. Eesti Miss teeb videofilmi / Evelyn Mikomägi ; interv. Valdo Jahilo

    Index Scriptorium Estoniae

    Mikomägi, Evelyn

    2001-01-01

    Eesti Miss Estonia 2000 Evelyn Mikomägi tegi koos sõbra, Sven-Olof Svenne Englundiga dokfilmi Küprosel peetud maailma suurimast iludusvõistlusest Miss Universe 2000. Neile kuulub ühisfirma "Living Frames" Rootsis, mille peategevus on suunatud 16mm ja 35mm filmide tootmisele

  10. COMPARATIVE ASSESSMENT OF FOREST COVER IN THE REPUBLICS OF MORDOVIA AND MARI EL ACCORDING TO THE RESULTS OF THE LANDSAT SATELITE IMAGES CLASSIFICATION

    National Research Council Canada - National Science Library

    E. S. Vdovin; A. V. Kaverin; E. N. Stvolkova

    2015-01-01

    Thestudy presents the results of an assessment of forest cover of the territories of the republics of Mordovia and Mari El on the color classification results of multispectral Landsat 8 in comparison...

  11. VISIONARY THINKER: LEADERSHIP AND MANAGEMENT IN WORKS OF MARY P. FOLLETT – LONG-TERM PERSPECTIVE IN THE COMPANIES OF THE REPUBLIC OF SERBIA

    National Research Council Canada - National Science Library

    Srdjan Nikezic; Radmila Mikovic; Dejana Prodanovic

    2014-01-01

    In her lectures, Mary P. Follett pointed to key moments of leadership, management, group membership, coordination and participation as relevant elements for the exploration of human relations that are of interest today...

  12. Marie-Sklodowska Curie, pioneer of Medical Physics and inspiration for women scientists; Marie-Sklodowska Curie, pionera de la Física Médica y fuente de inspiración para mujeres científi cas

    Energy Technology Data Exchange (ETDEWEB)

    Martín, G.

    2017-11-01

    The International Organization for Medical Physics (IOMP) celebrates annually the International Day of Medical Physics (IDMP) for which the 7th November, the birthday of Marie Sklodowska Curie, a most exceptional character in science at all and a pioneer of Medical Physics, has been chosen. This year, the IDMP is devoted to women in Medical Physics to honour the 150th anniversary of Marie Curie’s birthday. This article briefly outlines her outstanding personality, her fundamental discovery of the radioactivity and other scientific achievements for which she was awarded two Nobel Prizes, and her extensive collaboration with industry, far less well known. Finally, a brief review of the fundamental legacy she left the humanity in Medicine, Science and for women scientists is presented. [Spanish] La IOMP (Organización Internacional de Física Médica) celebra cada año el Día Internacional de la Física Médica (IDMP), el 7 de noviembre, en honor al nacimiento de Marie Sklodowska-Curie, un personaje excepcional en la historia de la ciencia y pionera de la Física Médica. Este año, en conmemoración del 150º aniversario de su nacimiento, el IDMP está dedicado a las mujeres en Física Médica. El siguiente artículo sobre Marie Curie describe brevemente su destacada personalidad, su descubrimiento fundamental de la radiactividad y otros logros científicos que la hicieron merecedora de dos Premios Nobel, y su extensa colaboración con la industria, faceta ésta desconocida en general. Finalmente, se hace un breve recorrido por el legado fundamental que dejó a la humanidad en Medicina, en Ciencia y para las mujeres científicas.

  13. Noorte staaride sügiseplaanid : Mari-Leen lõpetab keskkooli, Laura läheb USAsse, Birgit teeb plaati / Eveli Rebane

    Index Scriptorium Estoniae

    Rebane, Eveli

    2007-01-01

    Oma tulevikuplaanidest räägivad: lauljatar Mari-Leen Kaselaan, konkursi "Eesti otsib superstaari" võitja Birgit Õigemeel, lauljatar Laura Põldvere, filmi "Klass" peaosatäitjad Vallo Kirs ja Paula Solvak, Eesti esikäsipallur Mait Patrail, lauljatarid Mari-Liis Aasmäe ja Taisi Pettai ning konkursi "Eesti otsib superstaari" finaali pääsenud Nele Kirsipuu

  14. Ascorbic acid for the treatment of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Gess, Burkhard; Baets, Jonathan; De Jonghe, Peter; Reilly, Mary M; Pareyson, Davide; Young, Peter

    2015-12-11

    Charcot-Marie-Tooth disease (CMT) comprises a large group of different forms of hereditary motor and sensory neuropathy. The molecular basis of several CMT subtypes has been clarified during the last 20 years. Since slowly progressive muscle weakness and sensory disturbances are the main features of these syndromes, treatments aim to improve motor impairment and sensory disturbances to improve abilities. Pharmacological treatment trials in CMT are rare. This review was derived from a Cochrane review, Treatment for Charcot Marie Tooth disease, which will be updated via this review and a forthcoming title, Treatments other than ascorbic acid for Charcot-Marie-Tooth disease. To assess the effects of ascorbic acid (vitamin C) treatment for CMT. On 21 September 2015, we searched the Cochrane Neuromuscular Specialised Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE and LILACS for randomised controlled trials (RCTs) of treatment for CMT. We also checked clinical trials registries for ongoing studies. We included RCTs and quasi-RCTs of any ascorbic acid treatment for people with CMT. Where a study aimed to evaluate the treatment of general neuromuscular symptoms of people with peripheral neuropathy including CMT, we included the study if we were able to identify the effect of treatment in the CMT group. We did not include observational studies or case reports of ascorbic acid treatment in people with CMT. Two review authors (BG and JB) independently extracted the data and assessed study quality. Six RCTs compared the effect of oral ascorbic acid (1 to 4 grams) and placebo treatment in CMT1A. In five trials involving adults with CMT1A, a total of 622 participants received ascorbic acid or placebo. Trials were largely at low risk of bias. There is high-quality evidence that ascorbic acid does not improve the course of CMT1A in adults as measured by the CMT neuropathy score (0 to 36 scale) at 12 months (mean difference (MD) -0.37; 95

  15. José Carlos Mariátegui: el mensaje de Oriente. Aproximaciones al caso de India

    Directory of Open Access Journals (Sweden)

    María Ángela Cifuentes

    2014-06-01

    Full Text Available A partir de los escritos de José Carlos Mariátegui sobre Oriente, este artículo aborda el análisis del pensador peruano sobre la importancia de los movimientos independentistas de las colonias orientales de Asia y África posteriores a la Primera Guerra Mundial, y su interés en el caso de India. Se resalta la mirada crítica de Mariátegui respecto a la hegemonía de Occidente y el valor de las luchas por la independencia, vistas como la posibilidad de un cambio de orden político y social y, con ello, del surgimiento de una nueva conciencia.

  16. O marxismo indo-americano de Mariátegui e a polêmica com a III Internacional Comunista.

    Directory of Open Access Journals (Sweden)

    María Gabriela Guillén

    2012-05-01

    Full Text Available Partindo da perspectiva marxista indo-americana de José Carlos Mariátegui, o artigo visa a exposição de fatores teóricos e históricos que culminaram na polêmica com a III Internacional Comunista na América Latina. A problemática evidencia a originalidade do pensamento de Mariátegui, cujo eixo central é a interpretação dos fatos históricos, políticos e sociais latino-americanos sob a perspectiva dialética do desenvolvimento desigual e combinado para explicar a dinâmica particular da realidade peruana.

  17. Commentary: "Who was caring for Mary?" revisited: a call for all academic physicians caring for patients to focus on systems and quality improvement.

    Science.gov (United States)

    Southwick, Frederick S; Spear, Steven J

    2009-12-01

    Over 15 years have passed since Mary's near death (Annals of Internal Medicine. 1993;118:146-148). Disappointment in the care by fellow academic physicians persists; however, a reanalysis of her case through the lens of complex systems design and performance yields a more accurate and actionable perspective. Mary's suffering was not due to human failure alone. Human failure was provoked and exacerbated by broken processes including ambiguous assignments of responsibility; inadequate transfers of information and authority; unreliable or unavailable protocols for providing safe, effective treatment; and a failure to integrate the deep but narrow perspectives of individual specialists into a complete picture of Mary's condition. Her case exemplifies, in personal terms, many of the system challenges academic medical centers face: Faculty have other missions that can conflict with patient care; disease complexity is high, requiring input from multiple subspecialists; clinical departments serve as roadblocks to communication; and novice physicians, requiring close supervision, have primary responsibility for the day-to-day care of acutely ill patients. The academic physicians who first cared for Mary unwittingly accepted flawed systems, and they failed to work around them. At great monetary and emotional expense, last-minute heroics saved Mary. In a dysfunctional system, even the most conscientious physician may be viewed as uncaring. As Mary's case so clearly illustrates, patients and their families see the system and the physician as one. Only by working to improve the systems of delivery will academic physicians again be consistently viewed as caring.

  18. The Role of Rehabilitation in the Management of Patients with Charcot-Marie-Tooth Disease: Report of Two Cases

    OpenAIRE

    Erieta Nikolikj Dimitrova; Ivana Božinovikj; Simona Ristovska; Aleksandra Hadzieva Pejcikj; Aleksandra Kolevska; Mirjeta Hasani

    2016-01-01

    BACKGROUND: Charcot-Marie-Tooth (CMT) disease is a hereditary disease with signs of chronic non-progressive motor-sensory neuropathy which is characterised by symmetric muscle atrophy and weakness of the distal portion of lower extremities. AIM: The aim is to present two cases with peroneal muscular atrophy, applied rehabilitation procedures and rehabilitation outcome. MATERIAL AND METHODS: Patient DR, aged 51, and patient KH, aged 78. Both patients had weakness and pronounced atrophy...

  19. Effect of Cycocel on Some Physiological Characteristics of Tow Olive Cultivars (Mary and Mission under Drought Stress

    Directory of Open Access Journals (Sweden)

    V. Akbari

    2014-08-01

    Full Text Available Drought is the most important problems that restrict cultivation of horticultural crops in arid and semi-arid regions and olive (Olea europaea L. as an important fruit trees grows in these regions. In order to investigate the effect of cycocel treatment on some physioligical characteristics of two olive cultivars (Mary and Mission, under the condition of drought stress, a greenhouse experiment was conducted taking into account three factors of: cycocel at three levels (0, 500 and 1000 mg L-1, drought stress of three levels (irrigated at 5, 10 and 15 days intervals and tow olive cultivars (Mary and Mission in a factorial experiment in frame of randomized complete block design with three replicates for the lasted four months. The results showed that increased periods of drought have increased the number of stomata per unit leaf area and decreased net photosynthesis, transpiration rate, stomatal conductance and dry weight of leaf, stem and root in both cultivars. Also, results showed that both cycocel concentrations increased the number of stomata per unit leaf area, increase net photosynthesis, transpiration rate, stomatal conductance and dry weight of leaf but no significant difference in dry weight of stem and root was observed compared with the control. In above-mentioned parameters, Mission cultivar showed higher resistance to drought stress than the Mary cultivar. Collectively, results suggested that the use of cycocel can be improved in photosynthesis under drought stress conditions.

  20. [A study of development of medicine and science in the nineteenth century science fiction: biomedical experiments in Mary Shelley's Frankenstein].

    Science.gov (United States)

    Choo, Jae-Uk

    2014-12-01

    As the sciences advanced rapidly in the modern European world, outstanding achievements have been made in medicine, chemistry, biology, physiology, physics and others, which have been co-influencing each of the scientific disciplines. Accordingly, such medical and scientific phenomena began to be reflected in novels. In particular, Mary Shelley's Frankenstein includes the diverse aspects of the change and development in the medicine and science. Associated with medical and scientific information reflected in Frankenstein and Frankenstein's experiments in the text, accordingly, this research will investigate the aspects of medical and scientific development taking place in the nineteenth century in three ways. First, the medical and scientific development of the nineteenth century has been reviewed by summerizing both the information of alchemy in which Frankenstein shows his interest and the new science in general that M. Waldman introduces in the text. Second, the actual features of medical and scientific development have been examined through some examples of the experimental methods that M. Waldman implicitly uttered to Frankenstein. Third, it has been checked how the medical and scientific development is related to the main issues of mechanism and vitalism which can be explained as principles of life. Even though this research deals with the developmental process of medicine & science and origin & principles of life implied in Mary Shelley's Frankenstein, its significance is that it is the interdisciplinary research focussing on how deeply medical and scientific discourse of Mary Shelley's period has been imbedded in the nineteenth century novel.

  1. Creating an Online Exhibit in a First-Year Seminar: “Luxury Objects in the Age of Marie Antoinette”

    Directory of Open Access Journals (Sweden)

    Janie Vanpée

    2013-04-01

    Full Text Available How can students arrive at a closer understanding of the material culture that shaped the lives of the French aristocracy and nascent bourgeoisie of late eighteenth-century France? This is one of the challenges that students face in the first-year seminar, Re-Membering Marie Antoinette, as they study the multiple and conflicting ways that Marie Antoinette was and has been represented in biographies, portraits, memoirs, fiction, film, fashion, plays and pornographic pamphlets, records of her trial in 1793, and the spaces and activies that shaped her daily life. This article focuses on a series of scaffolded assignments that lead students to imagine what Marie Antoinette’s daily life might have been like by exploring the material culture of the period through the objects, decor, and activities depicted in Moreau le Jeune’s series of engravings, Le Monument du Costume, and the craftsmanship, labor, and social practices they entail as described in Diderot and d’Alembert’s Encyclopédie.

  2. Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot-Marie-Tooth disease

    Science.gov (United States)

    Madorsky, Irina; Opalach, Katherine; Waber, Amanda; Verrier, Jonathan D.; Solmo, Chelsea; Foster, Thomas; Dunn, William A; Notterpek, Lucia

    2009-01-01

    Charcot-Marie-Tooth type 1A (CMT1A) neuropathies linked to the misexpression of peripheral myelin protein 22 (PMP22) are progressive demyelinating disorders of the peripheral nervous system. In this study we asked whether dietary restriction by intermittent fasting (IF) could alleviate the neuropathic phenotype in the Trembler J (TrJ) mouse model of CMT1A. Our results show that neuropathic mice kept on a five month long IF regimen had improved locomotor performance compared to ad libitum (AL) fed littermates. The functional benefits of this dietary intervention are associated with an increased expression of myelin proteins combined with a thicker myelin sheath, less redundant basal lamina, and a reduction in aberrant Schwann cell proliferation. These morphological improvements are accompanied by a decrease in PMP22 protein aggregates, and enhanced expression of cytosolic chaperones and constituents of the autophagy-lysosomal pathway. These results indicate that dietary restriction is beneficial for peripheral nerve function in TrJ neuropathic mice, as it promotes the maintenance of locomotor performance. PMID:19320048

  3. The EGR2 gene is involved in axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Sevilla, T; Sivera, R; Martínez-Rubio, D; Lupo, V; Chumillas, M J; Calpena, E; Dopazo, J; Vílchez, J J; Palau, F; Espinós, C

    2015-12-01

    A three-generation family affected by axonal Charcot-Marie-Tooth disease (CMT) was investigated with the aim of discovering genetic defects and to further characterize the phenotype. The clinical, nerve conduction studies and muscle magnetic resonance images of the patients were reviewed. A whole exome sequencing was performed and the changes were investigated by genetic studies, in silico analysis and luciferase reporter assays. A novel c.1226G>A change (p.R409Q) in the EGR2 gene was identified. Patients presented with a typical, late-onset axonal CMT phenotype with variable severity that was confirmed in the ancillary tests. The in silico studies showed that the residue R409 is an evolutionary conserved amino acid. The p.R409Q mutation, which is predicted as probably damaging, would alter the conformation of the protein slightly and would cause a decrease of gene expression. This is the first report of an EGR2 mutation presenting as an axonal CMT phenotype with variable severity. This study broadens the phenotype of the EGR2-related neuropathies and suggests that the genetic testing of patients suffering from axonal CMT should include the EGR2 gene. © 2015 EAN.

  4. Quality of life in patients with Charcot-Marie-Tooth disease type 1A

    Directory of Open Access Journals (Sweden)

    Juliana B. Taniguchi

    2013-06-01

    Full Text Available We assessed the functional impairment in Charcot-Marie-Tooth resulting from 17p11.2-p12 duplication (CMT1A patients using the Short-Form Health Survey (SF-36, which is a quality of life questionnaire. Twenty-five patients of both genders aged ≥10 years with a positive molecular diagnosis of CMT1A were selected. Age- and gender-matched Control Group (without family history of neuropathy, and the sociodemographic and professional conditions similar to the patients' group were selected to compare the SF-36 results between them. The results showed that the majority quality of life impairments in CMT1A patients occurred in the social and emotional domains. Functional capacity also tended to be significantly affected; other indicators of physical impairment were preserved. In conclusion, social and emotional aspects are mostly neglected in the assistance provided to CMT1A Brazilian patients, and they should be better understood in order to offer global health assistance with adequate quality of life as a result.

  5. Impaired expression of ciliary neurotrophic factor in Charcot-Marie-Tooth type 1A neuropathy.

    Science.gov (United States)

    Nobbio, Lucilla; Fiorese, Fulvia; Vigo, Tiziana; Cilli, Michele; Gherardi, Gianfranco; Grandis, Marina; Melcangi, Roberto Cosimo; Mancardi, Gianluigi; Abbruzzese, Michele; Schenone, Angelo

    2009-05-01

    We investigated the contribution of Schwann cell-derived ciliary neurotrophic factor (CNTF) to the pathogenesis of Charcot-Marie-Tooth disease type 1A (CMT1A) and addressed the question as to whether it plays a role in the development of axonal damage observed in the disease, with aging. Ciliary neurotrophic factor was underexpressed in experimental CMT1A but not in other models of hereditary neuropathies. Sciatic nerve crush experiments and dosage of CNTF at different time points showed that expression of this trophic factor remained significantly lower in CMT1A rats than in normal controls; moreover, in uninjured CMT1A sciatic nerves CNTF levels further decreased with ageing, thus paralleling the molecular signs of axonal impairment, that is increased expression of non-phosphorylated neurofilaments and amyloid precursor protein. Administration of CNTF to dorsal root ganglia cultures reduced dephosphorylation of neurofilaments in CMT1A cultures, without improving demyelination. Taken together, these results provide further evidence that the production of CNTF by Schwann cells is markedly reduced in CMT1A. Moreover, the observations suggest that trophic support to the axon is impaired in CMT1A and that further studies on the therapeutic use of trophic factors or their derivatives in experimental and human CMT1A are warranted.

  6. Three Women in the administration: Lillian Moller Gilbreth, Mary Parker Follett and Joan Woodward

    Directory of Open Access Journals (Sweden)

    Norma Adela Paolini

    2016-06-01

    Full Text Available This paper aims to pay tribute to three pioneering women in the development of Management studies. It is a summary of the contributions made by these outstanding researchers, while respecting their specific characteristics, according to the different contexts in which they acted and the personal stamp that left a legacy to the discipline.1. Lillian Moller Gilbreth, a pioneer in the field, she developed with her husband working methods that laid the foundation of Ergonomics. After the death of Lillian Moller her husband continued with the employment and occupation activity, overcoming many obstacles related to feminine gender.2. Mary Parker Follett, leading researcher, due to her who given their sensitivity, was a pioneer in studies of humanist and social character in organizations.3. Joan Woodward, well known teacher and researcher, transcended for its relevant and rigorous studies in the manufacturing industry of England, focusing on the impact of technology in its structures.The main purpose is to bring information to the reader in order to give dimension and observe  their  contributions and proposals from a current perspective.Key words: pioneers, management humanistic approach, research.

  7. Sister Mary Joseph nodule as the presenting sign of disseminated prostate carcinoma

    Directory of Open Access Journals (Sweden)

    Deb Prabal

    2009-01-01

    Full Text Available Sister Mary Joseph′s nodule is referred to as metastasis of visceral malignancy to the umbilicus. Most common primaries are in the gastrointestinal or genital tract, while other locations are rare. We recently encountered a 76-year-old male who was referred to the surgery clinic with an erythematous nodule in the umbilicus measuring 6 cm in diameter with complaints of painless profuse hematuria. History revealed severe obstructive voiding symptoms of 2-year duration, along with significant loss of weight and difficulty in walking. A detailed examination showed hard nodular hepatomegaly, along with grade IV prostatomegaly. Serum prostate-specific antigen was 3069 ng/ml. A pelvic radiograph displayed multiple osteolytic lesions, while ultrasonography showed multiple iso- and hypoechoic lesions in both lobes of the liver, suggestive of metastasis. Histopathology of a Tru-cut biopsy of the prostate confirmed an adenocarcinoma (Gleason score 9 with umbilical metastasis. The patient was on regular follow-up and died 3 months later.

  8. Factors associated with incomplete childhood immunization among residents of St. Mary parish of Jamaica

    Science.gov (United States)

    Shuaib, Faisal; Kimbrough, Denise; Roofe, Michele; McGwin, G; Jolly, Pauline

    2010-01-01

    Aim To investigate factors associated with caregiver failure to complete immunizations for their children in the parish of St. Mary, Jamaica. Methods A case-control study was conducted with 50 cases defined as caregivers who failed to immunize their children and 179 controls defined as caregivers of children who were properly immunized. The cases were caregivers of children who were randomly selected from clinic records of children who failed to complete their immunization within the study period. Contrarily, controls were caregivers of children who were identified to have completed their immunization from a similar list. Cases and controls were visited at home and interviewed using a validated questionnaire. Cases and controls were compared in terms of socio-demographic, economic and other variables. Results Participants with less than secondary school education were more likely to be non-compliant (odds ratio [OR], 2.51, 95% confidence interval [CI], 1.06–5.97), while participants who were aware of legislation against non-compliance with immunization (OR, 0.35; 95% CI, 0.17–0.69) were less likely to fail to immunize their children. Conclusion Policy makers and program managers need to use established educational and communication channels to increase awareness about immunization especially among families with lower educational levels in the parish. PMID:21473405

  9. Interpretation of the key mythologems of Arthur legends within the novel series by Mary Stewart

    Directory of Open Access Journals (Sweden)

    Manitskaya Ekaterina Olegovna

    2015-09-01

    Full Text Available The article is devoted to the existence of myths in modern texts. As an example it was selected a series of novels about Merlin and King Arthur by British writer Mary Stewart, written in the twentieth century. In this novels, the author resorts to key mythologem of Arthurian myth, such as the sword Excalibur, the Holy Grail and the Round Table, turning them into symbols of pseudo-realities. Due to this the Sword and the Grail becom a Roman artifacts that Merlin is to give Arthur as real symbols of the power of predestination. Excalibur in this case becomes a symbol of the reunification of the country on both the political and the religious aspect. Grail turns into an object of false pursuit, because the role he must fulfill is given to Arthur. Roundtable loses its symbolic meaning: the author finds a historical explanation for this mythologeme and assigns a place in the Round Knights of Arthur’s house, which is really able to accommodate more than a hundred people at once. Thus, each of the myths in the text is not just a myth intended to make the myth-source recognizable, but also performs new functions ascribed by the author.

  10. Hereditary motor and sensory neuropathies or Charcot-Marie-Tooth diseases: an update.

    Science.gov (United States)

    Tazir, Meriem; Hamadouche, Tarik; Nouioua, Sonia; Mathis, Stephane; Vallat, Jean-Michel

    2014-12-15

    Hereditary motor and sensory neuropathies (HMSN) or Charcot-Marie-Tooth (CMT) diseases are the most common degenerative disorders of the peripheral nervous system. However, the frequency of the different subtypes varies within distinct populations. Although more than seventy clinical and genetic forms are known to date, more than 80% of CMT patients in Western countries have genetic abnormalities associated with PMP22, MPZ, MFN2 and GJB1. Given the considerable genetic heterogeneity of CMT, we emphasize the interest of both clinical and pathological specific features such that focused genetic testing could be performed. In this regard, peripheral nerve lesions in GDAP1 mutations (AR CMT1A), such as mitochondrial abnormalities, have been newly demonstrated. Otherwise, while demyelinating autosomal recessive CMT used to be classified as CMT4 (A, B, C …), we propose a simplified classification such as AR CMT1 (A, B, C …), and AR CMT2 for axonal forms. Also, we stress that next generation sequencing techniques, now considered to be the most efficient methods of genetic testing in CMT, will be helpful in molecular diagnosis and research of new genes involved. Finally, while no effective therapy is known to date, ongoing new therapeutic trials such as PXT3003 (a low dose combination of the three already approved drugs baclofen, naltrexone, and D-sorbitol) give hopes for potential curative treatment. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. X inactivation in females with X-linked Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Murphy, Sinéad M

    2012-07-01

    X-linked Charcot-Marie-Tooth disease (CMT1X) is the second most common inherited neuropathy, caused by mutations in gap junction beta-1 (GJB1). Males have a uniformly moderately severe phenotype while females have a variable phenotype, suggested to be due to X inactivation. We aimed to assess X inactivation pattern in females with CMT1X and correlate this with phenotype using the CMT examination score to determine whether the X inactivation pattern accounted for the variable phenotype in females with CMT1X. We determined X inactivation pattern in 67 females with CMT1X and 24 controls using the androgen receptor assay. We were able to determine which X chromosome carried the GJB1 mutation in 30 females. There was no difference in X inactivation pattern between patients and controls. In addition, there was no correlation between X inactivation pattern in blood and phenotype. A possible explanation for these findings is that the X inactivation pattern in Schwann cells rather than in blood may explain the variable phenotype in females with CMT1X.

  12. Developing spiritual and religious care competencies in practice: pilot of a Marie Curie blended learning event.

    Science.gov (United States)

    Smith, Tracy; Gordon, Tom

    2009-02-01

    The Marie Curie Cancer Care (2003) Spiritual and Religious Care Competencies for Specialist Palliative Care provide a common language for healthcare practitioners in the nebulous area of spiritual care. The development of a pilot blended learning event, as described in this paper, sought to integrate the competencies into practice by providing opportunities both online and in the classroom to explore this aspect of holistic care in depth. In the planning stages, multiprofessional focus groups determined the level of delivery, and emerging themes shaped the content. Self-awareness and reflection were key features and part of the overall process to improve competency. The features of the virtual learning environment (VLE) used were video, facilitated asynchronous discussion and direct links to key articles and documents, while interactive classroom activities built on prior learning. Evaluation covered all aspects of the course design from participant and facilitator perspectives. Participant comments were overwhelmingly positive in relation to the content and chosen delivery methods with concerns about online learning proving unfounded.

  13. Developing translational medicine professionals: the Marie Skłodowska-Curie action model.

    Science.gov (United States)

    Petrelli, Alessandra; Prakken, Berent J; Rosenblum, Norman D

    2016-11-29

    End goal of translational medicine is to combine disciplines and expertise to eventually promote improvement of the global healthcare system by delivering effective therapies to individuals and society. Well-trained experts of the translational medicine process endowed with profound knowledge of biomedical technology, ethical and clinical issues, as well as leadership and teamwork abilities are essential for the effective development of tangible therapeutic products for patients. In this article we focus on education and, in particular, we discuss how programs providing training on the broad spectrum of the translational medicine continuum have still a limited degree of diffusion and do not provide professional support and mentorship in the long-term, resulting in the lack of well established professionals of translational medicine (TMPs) in the scientific community. Here, we describe the Marie Skłodowska-Curie Actions program ITN-EUtrain (EUropean Translational tRaining for Autoimmunity & Immune manipulation Network) where training on the Translational Medicine machinery was integrated with education on professional and personal skills, mentoring, and a long-lasting network of TMPs.

  14. Developments in damage assessment by Marie Skłodowska-Curie TRUSS ITN project

    Science.gov (United States)

    González, A.

    2017-05-01

    The growth of cities, the impacts of climate change and the massive cost of providing new infrastructure provide the impetus for TRUSS (Training in Reducing Uncertainty in Structural Safety), a €3.7 million Marie Skłodowska-Curie Action Innovative Training Network project funded by EU’s Horizon 2020 programme, which aims to maximize the potential of infrastructure that already exists (http://trussitn.eu). For that purpose, TRUSS brings together an international, inter-sectoral and multidisciplinary collaboration between five academic and eleven industry institutions from five European countries. The project covers rail and road infrastructure, buildings and energy and marine infrastructure. This paper reports progress in fields such as advanced sensor-based structural health monitoring solutions - unmanned aerial vehicles, optical backscatter reflectometry, monitoring sensors mounted on vehicles, … - and innovative algorithms for structural designs and short- and long-term assessments of buildings, bridges, pavements, ships, ship unloaders, nuclear components and wind turbine towers that will support infrastructure operators and owners in managing their assets.

  15. Ciencia e industria en el desarrollo de la radiactividad: el caso de Marie Curie

    Directory of Open Access Journals (Sweden)

    Roqué, Xavier

    1997-01-01

    Full Text Available Not available.Se argumenta que Marie Curie desarrolló sus investigaciones en radiactividad en estrecha relación con la industria de los radioelementos. Esta relación incluyó desde el desarrollo de procedimientos de extracción para diversas sustancias radiactivas, hasta la promoción de su propio laboratorio industrial. La actividad industrial de Curie se aviene mal con su imagen heroica de científica pura, sacrificada y carente de medios, imagen que, paradójicamente, se retrotrae a las campañas de Curie en los años 1920 por dotar a su laboratorio con «medios de acción industriales». Se verá que los valores dominantes del medio científico francés favorecieron la propagación selectiva de la imagen heroica de Curie, que fue luego aceptada acríticamente por la historiografía de la física del siglo XX.

  16. Benefits of interval-training on fatigue and functional capacities in Charcot-Marie-Tooth disease.

    Science.gov (United States)

    El Mhandi, Lhassan; Millet, Guillaume Y; Calmels, Paul; Richard, Antoine; Oullion, Roger; Gautheron, Vincent; Féasson, Léonard

    2008-05-01

    Exercise intolerance and undue fatigue are common complaints in patients with Charcot-Marie-Tooth (CMT) disease. Reduced physical ability is due directly to the disease, but it is also due to physical deconditioning. The aim of this study was to test whether 24 weeks of interval-training exercise (ITE) cycling can significantly improve physiological, neuromuscular, and functional capacities and alleviate fatigue in CMT patients. Eight CMT patients (4 CMT1A and 4 CMT2) participated in ITE for 3 nonconsecutive days per week. Cardiovascular fitness, muscle strength, fatigue resistance, and functional capacities were measured before and after 12 weeks of supervised hospital training and again after another 12 weeks of unsupervised home training. Training was well tolerated. There were significant improvements in cardiorespiratory capacities, isokinetic concentric strength, and functional ability measurements. All patients experienced an improvement in their self-reported visual analogic scale for fatigue and pain during training. However, there was no significant change in their isometric force production and indices of fatigue resistance after training. Although the improvement in exercise tolerance may be due in part to reversal of the deconditioning effect of their related sedentary lifestyle, this clinical trial suggests that ITE can benefit CMT patients especially in their functional performance and subjective perception of pain and fatigue. Moreover, the improvement observed at the end of the first supervised period ITE was maintained after the second unsupervised home period, although there was no further improvement in performance and tolerance.

  17. AAV1.NT-3 gene therapy for charcot-marie-tooth neuropathy.

    Science.gov (United States)

    Sahenk, Zarife; Galloway, Gloria; Clark, Kelly Reed; Malik, Vinod; Rodino-Klapac, Louise R; Kaspar, Brian K; Chen, Lei; Braganza, Cilwyn; Montgomery, Chrystal; Mendell, Jerry R

    2014-03-01

    Charcot-Marie-Tooth (CMT) neuropathies represent a heterogeneous group of peripheral nerve disorders affecting 1 in 2,500 persons. One variant, CMT1A, is a primary Schwann cell (SC) disorder, and represents the single most common variant. In previous studies, we showed that neurotrophin-3 (NT-3) improved the trembler(J) (Tr(J)) mouse and also showed efficacy in CMT1A patients. Long-term treatment with NT-3 was not possible related to its short half-life and lack of availability. This led to considerations of NT-3 gene therapy via adenoassociated virus (AAV) delivery to muscle, acting as secretory organ for widespread distribution of this neurotrophic agent. In the Tr(J) model of demyelinating CMT, rAAV1.NT-3 therapy resulted in measurable NT-3 secretion levels in blood sufficient to provide improvement in motor function, histopathology, and electrophysiology of peripheral nerves. Furthermore, we showed that the compound muscle action potential amplitude can be used as surrogate for functional improvement and established the therapeutic dose and a preferential muscle-specific promoter to achieve sustained NT-3 levels. These studies of intramuscular (i.m.) delivery of rAAV1.NT-3 serve as a template for future CMT1A clinical trials with a potential to extend treatment to other nerve diseases with impaired nerve regeneration.

  18. Designing long-term fish community assessments in connecting channels: Lessons from the Saint Marys River

    Science.gov (United States)

    Schaeffer, Jeff; Rogers, Mark W.; Fielder, David G.; Godby, Neal; Bowen, Anjanette K.; O'Connor, Lisa; Parrish, Josh; Greenwood, Susan; Chong, Stephen; Wright, Greg

    2014-01-01

    Long-term surveys are useful in understanding trends in connecting channel fish communities; a gill net assessment in the Saint Marys River performed periodically since 1975 is the most comprehensive connecting channels sampling program within the Laurentian Great Lakes. We assessed efficiency of that survey, with intent to inform development of assessments at other connecting channels. We evaluated trends in community composition, effort versus estimates of species richness, ability to detect abundance changes for four species, and effects of subsampling yellow perch catches on size and age-structure metrics. Efficiency analysis revealed low power to detect changes in species abundance, whereas reduced effort could be considered to index species richness. Subsampling simulations indicated that subsampling would have allowed reliable estimates of yellow perch (Perca flavescens) population structure, while greatly reducing the number of fish that were assigned ages. Analyses of statistical power and efficiency of current sampling protocols are useful for managers collecting and using these types of data as well as for the development of new monitoring programs. Our approach provides insight into whether survey goals and objectives were being attained and can help evaluate ability of surveys to answer novel questions that arise as management strategies are refined.

  19. VICTORIAN FEMME FATALE IN MARY ELIZABETH BRADDON‟S NOVEL ENTITLED LADY AUDLEY‟S SECRET

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    Ratna Asmarani

    2017-04-01

    Full Text Available The aim of the paper entitled ―Victorian Femme Fatale in Mary Elizabeth Braddon‘s Novel Entitled Lady Audley‟s Secret‖ is to analyze the intricate life of the female main character as a representation of Victorian femme fatale. Feminist criticism and gynocritics are used as a frame of analysis supported by the concepts of femme fatale, fatalism, and Victorian femininity. The result indicates that although femme fatale is fatal to men, she leads a fatalistic life in a patriarchal Victorian society. Her success to pursue a wealthy life using her femininity is short-lived followed by years of exile in a private and luxurious asylum. Through her portrayal of the female main character‘s life as a femme fatale, the female writer launches two-edged criticism. She criticizes the woman who exploits her femininity to get excessive material gain and at the same time she criticizes the Victorian society which prevents a single (-parent woman to have a decent life using her skills not her femininity.

  20. Charcot Marie Tooth 2B Peripheral Sensory Neuropathy: How Rab7 Mutations Impact NGF Signaling?

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    Harry Liu

    2017-02-01

    Full Text Available Charcot-Marie-Tooth 2B peripheral sensory neuropathy (CMT2B is a debilitating autosomal dominant hereditary sensory neuropathy. Patients with this disease lose pain sensation and frequently need amputation. Axonal dysfunction and degeneration of peripheral sensory neurons is a major clinical manifestation of CMT2B. However, the cellular and molecular pathogenic mechanisms remain undefined. CMT2B is caused by missense point mutations (L129F, K157N, N161T/I, V162M in Rab7 GTPase. Strong evidence suggests that the Rab7 mutation(s enhances the cellular levels of activated Rab7 proteins, thus resulting in increased lysosomal activity and autophagy. As a consequence, trafficking and signaling of neurotrophic factors such as nerve growth factor (NGF in the long axons of peripheral sensory neurons are particularly vulnerable to premature degradation. A “gain of toxicity” model has, thus, been proposed based on these observations. However, studies of fly photo-sensory neurons indicate that the Rab7 mutation(s causes a “loss of function”, resulting in haploinsufficiency. In the review, we summarize experimental evidence for both hypotheses. We argue that better models (rodent animals and human neurons of CMT2B are needed to precisely define the disease mechanisms.

  1. Common Murre (Uria aalge) attendance patterns at Cape St. Mary's, Newfoundland

    Science.gov (United States)

    Piatt, John F.; McLagan, Ruth L.

    1987-01-01

    Attendance patterns of common murres (Uria aalge) at Cape St. Mary's, Newfoundland, were observed during hatching to post-fledging periods of 1980 to 1984. Six study plots on breeding ledges (ca. 450 birds total) and a "club" on the water were monitored for seasonal fluctuations in numbers attending. Attendance on ledges was similar between years, being relatively stable from hatching through to median fledging, and declining steadily thereafter. Attendance at the club usually peaked between median hatching and fledging, then declined rapidly during the fledging period. Numbers of murres attending neighboring study plots were often significantly correlated, but correlations were much weaker between distant plots. There were few significant correlations between attendance and wind speed or tidal oscillations in any year of study. Numbers of murres attending individual study plots varied significantly between years; four declined, one increased, and one showed no significant change. Overall, there was a small decline in total numbers of murres attending all study plots between 1980 and 1984.

  2. From secure dependency to attachment: Mary Ainsworth's integration of Blatz's security theory into Bowlby's attachment theory.

    Science.gov (United States)

    van Rosmalen, Lenny; van der Horst, Frank C P; van der Veer, René

    2016-02-01

    John Bowlby is generally regarded as the founder of attachment theory, with the help of Mary Ainsworth. Through her Uganda and Baltimore studies Ainsworth provided empirical evidence for attachment theory, and she contributed the notion of the secure base and exploratory behavior, the Strange Situation Procedure and its classification system, and the notion of maternal sensitivity. On closer scrutiny, many of these contributions appear to be heavily influenced by William Blatz and his security theory. Even though Blatz's influence on Ainsworth has been generally acknowledged, this article, partly based on understudied correspondence from several personal archives, is the first to show which specific parts of attachment theory can be traced back directly to Blatz and his security theory. When Ainsworth started working with Bowlby in the 1950s, around the time he turned to evolutionary theory for an explanation of his findings, she integrated much of Blatzian security theory into Bowlby's theory in the making and used her theoretical and practical experience to enrich attachment theory. Even though Blatz is hardly mentioned nowadays, several of his ideas live on in attachment theory. (c) 2016 APA, all rights reserved).

  3. The utilization of occupational therapy services for persons with Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Matyjasik-Liggett, Maria; Wittman, Peggy

    2013-07-01

    The purpose of this study was to investigate the utilization of occupational therapy services in persons with Charcot-Marie-Tooth (CMT) disease, to better understand if services are being provided, the types of interventions being provided, and satisfaction of services. Using survey methods, an online questionnaire was made available to persons with CMT listed on association websites worldwide. One hundred and fifteen persons with CMT, residing in all geographical regions within the United States and seven other countries participated in the study. Around half of all participants had received occupational therapy services. Twelve interventions were identified as being provided for persons with CMT. Although the majority of individuals receiving occupational therapy services did not feel like it improved their quality of life, the majority of individuals would recommend occupational therapy services to others and would return to an occupational therapist. Of those participants not receiving occupational therapy, the majority felt they would benefit from occupational therapy services. The results suggest that occupational therapy services are not being well utilized for this population. A low response rate limits generalization, thus further research is necessary.

  4. Oral Health, Temporomandibular Disorder, and Masticatory Performance in Patients with Charcot-Marie-Tooth Type 2

    Science.gov (United States)

    Rezende, Rejane L. S.; Bonjardim, Leonardo R.; Neves, Eduardo L. A.; Santos, Lidiane C. L.; Nunes, Paula S.; Garcez, Catarina A.; Souza, Cynthia C.; Araújo, Adriano A. S.

    2013-01-01

    Background. The aim of this study was to evaluate the oral health status of temporomandibular disorders (TMD) and bruxism, as well as to measure masticatory performance of subjects with Charcot-Marie-Tooth type 2 (CMT2). Methods and Results. The average number of decayed, missing, and filled teeth (DMFT) for both groups, control (CG) and CMT2, was considered low (CG = 2.46; CMT2 = 1.85, P = 0.227). The OHIP-14 score was considered low (CG = 2.86, CMT2 = 5.83, P = 0.899). The prevalence of self-reported TMD was 33.3% and 38.9% (P = 0.718) in CG and CMT2 respectively and for self-reported bruxism was 4.8% (CG) and 22.2% (CMT2), without significant difference between groups (P = 0.162). The most common clinical sign of TMD was masseter (CG = 38.1%; CMT2 = 66.7%) and temporalis (CG = 19.0%; GCMT2 = 33.3%) muscle pain. The geometric mean diameter (GMD) was not significantly different between groups (CG = 4369; CMT2 = 4627, P = 0.157). Conclusion. We conclude that the CMT2 disease did not negatively have influence either on oral health status in the presence and severity of TMD and bruxism or on masticatory performance. PMID:24391462

  5. 17p duplicated Charcot-Marie-Tooth 1A: characteristics of a new population.

    Science.gov (United States)

    Marques, Wilson; Freitas, Marcos R; Nascimento, Osvaldo J M; Oliveira, Acary B; Calia, Leandro; Melo, Ailton; Lucena, Rita; Rocha, Vera; Barreira, Amilton A

    2005-08-01

    The most frequent type of Charcot-Marie-Tooth (CMT) neuropathy is that associated with the 17p11.2-p12 chromosome duplication, whose characteristics have been well described in European and North American populations. In this study, we analyzed a Brazilian population exhibiting the mutation, found in 57 patients from 42 families (79%) of a cohort of 53 families with demyelinating CMT. Almost 20% of the duplicated cases were sporadic. In 77% of the duplicated families the mutation event occurred in the hot spot area of the CMT1A-Rep region. Forty-five percent of patients were females, 84% were Caucasians and 13% of African descent. Distal limb weakness was the most frequent abnormality, appearing in 84% of patients, although uncommon manifestations such as severe proximal weakness, floppy baby syndrome, diaphragmatic weakness and severe scoliosis were also observed. One patient was wheelchair-bound, and three suffered severe hand weakness. Sensory abnormalities were detected in 84% of the cases, but 80% were unaware of this impairment. Twelve patients complained of positive sensory manifestations such as pain and paresthesias. Progression was reported by 40%. Motor conduction velocities in the upper limbs were always less than 35 m/s, and less than 30.4 m/s in the peroneal nerve. The findings of this study expand the clinical spectrum of the disease.

  6. Linkage localization of X-linked Charcot-Marie-Tooth disease

    Energy Technology Data Exchange (ETDEWEB)

    Bergoffen, J. (Children' s Hospital, Philadelphia, PA (United States) Univ. of Pennsylvania, Philadelphia (United States)); Trofatter, J.; Haines, J.L. (Massachusetts General Hospital, Boston (United States)); Pericak-Vance, M.A. (Duke Univ., Durham, NC (United States)); Chance, P.F. (Univ. of Utah, Salt Lake City (United States)); Fischbeck, K.H. (Univ. of Pennsylvania, Philadelphia (United States))

    1993-02-01

    Charcot-Marie-Tooth disease (CMT), also known as hereditary motor and sensory neuropathy, is a heterogeneous group of slowly progressive, degenerative disorders of peripheral nerve. X-linked CMT (CMTX) (McKusick 302800), a subdivision of type I, or demyelinating, CMT is an X-linked dominant condition with variable penetrance. Previous linkage analysis using RFLPs demonstrated linkage to markers on the proximal long and short arms of the X chromosome, with the more likely localization on the proximal long arm of the X chromosome. Available variable simple-sequence repeats (VSSRs) broaden the possibilities for linkage analysis. This paper presents new linkage data and recombination analysis derived from work with four VSSR markers - AR, PGKP1, DXS453, and DXYS1X - in addition to analysis using RFLP markers described elsewhere. These studies localize the CMTX gene to the proximal Xq segment between PGKP1 (Xq11.2-12) and DXS72 (Xq21.1), with a combined maximum multipoint lod score of 15.3 at DXS453 ([theta] = 0). 32 refs., 3 figs., 2 tabs.

  7. Dysregulation of ErbB Receptor Trafficking and Signaling in Demyelinating Charcot-Marie-Tooth Disease.

    Science.gov (United States)

    Lee, Samuel M; Chin, Lih-Shen; Li, Lian

    2017-01-01

    Charcot-Marie-Tooth (CMT) disease is the most common inherited peripheral neuropathy with the majority of cases involving demyelination of peripheral nerves. The pathogenic mechanisms of demyelinating CMT remain unclear, and no effective therapy currently exists for this disease. The discovery that mutations in different genes can cause a similar phenotype of demyelinating peripheral neuropathy raises the possibility that there may be convergent mechanisms leading to demyelinating CMT pathogenesis. Increasing evidence indicates that ErbB receptor-mediated signaling plays a major role in the control of Schwann cell-axon communication and myelination in the peripheral nervous system. Recent studies reveal that several demyelinating CMT-linked proteins are novel regulators of endocytic trafficking and/or phosphoinositide metabolism that may affect ErbB receptor signaling. Emerging data have begun to suggest that dysregulation of ErbB receptor trafficking and signaling in Schwann cells may represent a common pathogenic mechanism in multiple subtypes of demyelinating CMT. In this review, we focus on the roles of ErbB receptor trafficking and signaling in regulation of peripheral nerve myelination and discuss the emerging evidence supporting the potential involvement of altered ErbB receptor trafficking and signaling in demyelinating CMT pathogenesis and the possibility of modulating these trafficking and signaling processes for treating demyelinating peripheral neuropathy.

  8. MARIS plays important roles in Arabidopsis pollen tube and root hair growth.

    Science.gov (United States)

    Liao, Hong-Ze; Zhu, Meng-Meng; Cui, Hong-Hui; Du, Xin-Yu; Tang, Yu; Chen, Li-Qun; Ye, De; Zhang, Xue-Qin

    2016-11-01

    In flowering plants, male gametes are delivered to female gametes for double fertilization through pollen tubes. Therefore, pollen tube growth is crucial for double fertilization. Despite its importance to sexual reproduction, genetic mechanisms of pollen tube growth remain poorly understood. In this study, we characterized the receptor-like cytoplasmic protein kinase (RLCK) gene, MARIS (MRI) that plays critical roles in pollen tube growth. MRI is preferentially expressed in pollen grains, pollen tubes and roots. Mutation in MRI by a Ds insertion led to a burst of pollen tubes after pollen germination. Pollen-rescue assay by pollen and pollen tube-specific expression of MRI in the mri-4 mutant showed that loss of MRI function also severely affected root hair elongation. MRI protein interacted with the protein kinase OXIDATIVE SIGNAL INDUCIBLE1 (OXI1) in the in vitro and in vivo assays, which functions in plant defence and root hair development, and was phosphorylated by OXI1 in vitro. Our results suggest that MRI plays important roles in pollen tube growth and may function in root hair elongation through interaction with OXI1. © 2016 Institute of Botany, Chinese Academy of Sciences.

  9. Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Madorsky, Irina; Opalach, Katherine; Waber, Amanda; Verrier, Jonathan D; Solmo, Chelsea; Foster, Thomas; Dunn, William A; Notterpek, Lucia

    2009-04-01

    Charcot-Marie-Tooth type 1A (CMT1A) neuropathies linked to the misexpression of peripheral myelin protein 22 (PMP22) are progressive demyelinating disorders of the peripheral nervous system. In this study we asked whether dietary restriction by intermittent fasting (IF) could alleviate the neuropathic phenotype in the Trembler J (TrJ) mouse model of CMT1A. Our results show that neuropathic mice kept on a five month long IF regimen had improved locomotor performance compared to ad libitum (AL) fed littermates. The functional benefits of this dietary intervention are associated with an increased expression of myelin proteins combined with a thicker myelin sheath, less redundant basal lamina, and a reduction in aberrant Schwann cell proliferation. These morphological improvements are accompanied by a decrease in PMP22 protein aggregates, and enhanced expression of cytosolic chaperones and constituents of the autophagy-lysosomal pathway. These results indicate that dietary restriction is beneficial for peripheral nerve function in TrJ neuropathic mice, as it promotes the maintenance of locomotor performance.

  10. Oral Health, Temporomandibular Disorder, and Masticatory Performance in Patients with Charcot-Marie-Tooth Type 2

    Directory of Open Access Journals (Sweden)

    Rejane L. S. Rezende

    2013-01-01

    Full Text Available Background. The aim of this study was to evaluate the oral health status of temporomandibular disorders (TMD and bruxism, as well as to measure masticatory performance of subjects with Charcot-Marie-Tooth type 2 (CMT2. Methods and Results. The average number of decayed, missing, and filled teeth (DMFT for both groups, control (CG and CMT2, was considered low (CG = 2.46; CMT2 = 1.85, P=0.227. The OHIP-14 score was considered low (CG = 2.86, CMT2 = 5.83, P=0.899. The prevalence of self-reported TMD was 33.3% and 38.9% (P=0.718 in CG and CMT2 respectively and for self-reported bruxism was 4.8% (CG and 22.2% (CMT2, without significant difference between groups (P=0.162. The most common clinical sign of TMD was masseter (CG = 38.1%; CMT2 = 66.7% and temporalis (CG = 19.0%; GCMT2 = 33.3% muscle pain. The geometric mean diameter (GMD was not significantly different between groups (CG = 4369; CMT2 = 4627, P=0.157. Conclusion. We conclude that the CMT2 disease did not negatively have influence either on oral health status in the presence and severity of TMD and bruxism or on masticatory performance.

  11. Oral health, temporomandibular disorder, and masticatory performance in patients with Charcot-Marie-Tooth type 2.

    Science.gov (United States)

    Rezende, Rejane L S; Bonjardim, Leonardo R; Neves, Eduardo L A; Santos, Lidiane C L; Nunes, Paula S; Garcez, Catarina A; Souza, Cynthia C; Araújo, Adriano A S

    2013-01-01

    The aim of this study was to evaluate the oral health status of temporomandibular disorders (TMD) and bruxism, as well as to measure masticatory performance of subjects with Charcot-Marie-Tooth type 2 (CMT2). The average number of decayed, missing, and filled teeth (DMFT) for both groups, control (CG) and CMT2, was considered low (CG = 2.46; CMT2 = 1.85, P = 0.227). The OHIP-14 score was considered low (CG = 2.86, CMT2 = 5.83, P = 0.899). The prevalence of self-reported TMD was 33.3% and 38.9% (P = 0.718) in CG and CMT2 respectively and for self-reported bruxism was 4.8% (CG) and 22.2% (CMT2), without significant difference between groups (P = 0.162). The most common clinical sign of TMD was masseter (CG = 38.1%; CMT2 = 66.7%) and temporalis (CG = 19.0%; GCMT2 = 33.3%) muscle pain. The geometric mean diameter (GMD) was not significantly different between groups (CG = 4369; CMT2 = 4627, P = 0.157). We conclude that the CMT2 disease did not negatively have influence either on oral health status in the presence and severity of TMD and bruxism or on masticatory performance.

  12. Behavioural profiling of a murine Charcot-Marie-Tooth disease type 1A model.

    Science.gov (United States)

    Norreel, J C; Jamon, M; Riviere, G; Passage, E; Fontes, M; Clarac, F

    2001-04-01

    Different features of motor behaviour were studied on a transgenic mouse model of Charcot-Marie-Tooth's disease (CMT). Mutants with 4 or 7 copies of the human PMP22 gene leading to a phenotype significantly close to CMT's disease type 1A were compared with control animals. The aim of the study was to validate this transgenic model and to characterise the impairments occurring in the various lines. Three main types of analysis were performed in 2-month-old mice without any peculiar visible deficit: (i) a study of standardised clinical tests (SHIRPA protocol) demonstrated that only a few motor deficits were expressed; (ii) a measurement of general spontaneous activity by means of a commercial video-tracking system was performed and revealed that the main spontaneous activities were identical in the three lines with, however, some slight localised modifications; and, (iii) by contrast, the three lines respond very differently to the footprints, grip strength, splay test and rotarod test. Even in lines with a significantly limited copy number of the transgene, we observed and quantified impairments. In conclusion, mutants of CMT1A seem to be a very pertinent model of this human pathology and will certainly be useful for therapeutic procedures and for theoretical studies on this disease.

  13. Clinical and Pathological Variation of Charcot-Marie-Tooth 1A in a Large Chinese Cohort

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    Rui Wu

    2017-01-01

    Full Text Available Charcot-Marie-Tooth 1A (CMT1A caused by peripheral myelin protein 22 (PMP22 gene duplication is the most common form of hereditary polyneuropathy. Twenty-four genetically confirmed CMT1A patients with sural nerve biopsies were enrolled in this study. The clinical picture included a great variability of phenotype with mean onset age of 22.2±14.5 years (1–55 years. Pathologically, we observed a severe reduction in myelinated fiber density showing three types of changes: pure onion bulb formation in 3 cases (12.5%, onion bulb formation with axonal sprouts in 10 cases (41.7%, and focally thickened myelin with onion bulb formation or/and axonal sprouts in 11 cases (45.8%. We observed no significant correlation between nerve fiber density and disease duration. There was no significant difference between the 3 pathological types in terms of clinical manifestations, nerve fiber density, and g-ratio. Our study indicates that there is marked variability in the age of onset of CMT1A, as well as significant pathological changes without deterioration with the development of the disease. Focally thickened myelin is another common morphological feature of demyelination.

  14. A Mutation in PMP2 Causes Dominant Demyelinating Charcot-Marie-Tooth Neuropathy.

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    Young Bin Hong

    2016-02-01

    Full Text Available Charcot-Marie-Tooth disease (CMT is a heterogeneous group of peripheral neuropathies with diverse genetic causes. In this study, we identified p.I43N mutation in PMP2 from a family exhibiting autosomal dominant demyelinating CMT neuropathy by whole exome sequencing and characterized the clinical features. The age at onset was the first to second decades and muscle atrophy started in the distal portion of the leg. Predominant fatty replacement in the anterior and lateral compartment was similar to that in CMT1A caused by PMP22 duplication. Sural nerve biopsy showed onion bulbs and degenerating fibers with various myelin abnormalities. The relevance of PMP2 mutation as a genetic cause of dominant CMT1 was assessed using transgenic mouse models. Transgenic mice expressing wild type or mutant (p.I43N PMP2 exhibited abnormal motor function. Electrophysiological data revealed that both mice had reduced motor nerve conduction velocities (MNCV. Electron microscopy revealed that demyelinating fibers and internodal lengths were shortened in both transgenic mice. These data imply that overexpression of wild type as well as mutant PMP2 also causes the CMT1 phenotype, which has been documented in the PMP22. This report might expand the genetic and clinical features of CMT and a further mechanism study will enhance our understanding of PMP2-associated peripheral neuropathy.

  15. Conservation Action Planning: Lessons learned from the St. Marys River watershed biodiversity conservation planning process

    Science.gov (United States)

    Patterson, Tamatha A.; Grundel, Ralph

    2014-01-01

    Conservation Action Planning (CAP) is an adaptive management planning process refined by The Nature Conservancy (TNC) and embraced worldwide as the Open Standards for the Practice of Conservation. The CAP process facilitates open, multi-institutional collaboration on a common conservation agenda through organized actions and quantified results. While specifically designed for conservation efforts, the framework is adaptable and flexible to multiple scales and can be used for any collaborative planning effort. The CAP framework addresses inception; design and development of goals, measures, and strategies; and plan implementation and evaluation. The specific components of the CAP include defining the project scope and conservation targets; assessing the ecological viability; ascertaining threats and surrounding situation; identifying opportunities and designing strategies for action; and implementing actions and monitoring results. In 2007, TNC and a multidisciplinary graduate student team from the University of Michigan's School of Natural Resources and Environment initiated a CAP for the St. Marys River, the connecting channel between Lake Superior and Lake Huron, and its local watershed. The students not only gained experience in conservation planning, but also learned lessons that notably benefited the CAP process and were valuable for any successful collaborative effort—a dedicated core team improved product quality, accelerated the timeline, and provided necessary support for ongoing efforts; an academic approach in preparation for engagement in the planning process brought applicable scientific research to the forefront, enhanced workshop facilitation, and improved stakeholder participation; and early and continuous interactions with regional stakeholders improved cooperation and built a supportive network for collaboration.

  16. Charcot-Marie-Tooth Disease 1X Simulating Paraparetic Guillain-Barre Syndrome.

    Science.gov (United States)

    Parissis, Dimitrios; Ioannidis, Panagiotis; Papadopoulos, Georgios; Karacostas, Dimitrios

    2017-11-01

    X-linked Charcot-Marie-Tooth disease (CMT 1X) is the second most common form of inherited demyelinating neuropathy. It is established that patients suffering from CMT 1X can have episodes of hemiparesis, paraparesis, quadriparesis, ataxia, aphasia, and dysarthria, which can be fully reversible, and 'trigger' factors for these episodes are usually febrile illness, high altitudes, hyperventilation, and physical activity. We describe a 22-year-old patient with a history of viral infection and sleep deprivation who presented to our department because of acute difficulty in walking and neurophysiological findings suggesting Guillain-Barre syndrome. The patient's phenotype was compatible with CMT disease and within hours he showed remarkable improvement of his muscle strength without receiving any medical treatment. Any other metabolic, infectious, vasculitic, hematological, paraneoplastic, or infiltrative cause of polyneuropathy was excluded with laboratory work-up. Diagnosis of CMT 1X was confirmed with repeated neurophysiological study and genetic testing of his and his mother's blood, demonstrating the Arg75Trp [CGG to TGG,(R75W)] mutation on exon2 of gap junction protein beta 1. CMT 1X should be considered in patients with a phenotype compatible with the disease, rapid improvement of their clinical manifestations, and neurophysiological findings consistent with a hereditary, demyelinating neuropathy.

  17. Mary Poppins and the Soviet Pilgrimage: P.L.Travers's Moscow Excursion (1934

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    John McNair

    2013-02-01

    Full Text Available Like the journey it chronicles, Moscow Excursion, P.L.Travers’s account of her 1932 visit to Russia, was in part inspired by the genre it effectively parodies: the ‘Soviet pilgrimage’ ‘truth about Russia’ narrative characteristic of the Stalin decades and exemplified (in the Australian context by Katharine Susannah Prichard’s The Real Russia, also published in 1934. The paper examines the ways in which Travers’s book is written against this genre to produce an avowedly ‘un-political’ record whose narrator rejects the restrictions of organized travel, and whose idiosyncratic and critical observations on Soviet reality contrast with the admiration of her more orthodox fellow-travellers for the usual showcase institutions on the official itinerary. At the same time, it is argued that in its blend of self-deprecating irony, whimsy and disillusioned idealism Moscow Excursion suggests parallels with Travers’s personal quest for ‘the truth’ and even with Mary Poppins, published only two months later.

  18. Two Novel De Novo GARS Mutations Cause Early-Onset Axonal Charcot-Marie-Tooth Disease.

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    Yi-Chu Liao

    Full Text Available Mutations in the GARS gene have been identified in a small number of patients with Charcot-Marie-Tooth disease (CMT type 2D or distal spinal muscular atrophy type V, for whom disease onset typically occurs during adolescence or young adulthood, initially manifesting as weakness and atrophy of the hand muscles. The role of GARS mutations in patients with inherited neuropathies in Taiwan remains elusive.Mutational analyses of the coding regions of GARS were performed using targeted sequencing of 54 patients with molecularly unassigned axonal CMT, who were selected from 340 unrelated CMT patients. Two heterozygous mutations in GARS, p.Asp146Tyr and p.Met238Arg, were identified; one in each patient. Both are novel de novo mutations. The p.Asp146Tyr mutation is associated with a severe infantile-onset neuropathy and the p.Met238Arg mutation results in childhood-onset disability.GARS mutations are an uncommon cause of CMT in Taiwan. The p.Asp146Tyr and p.Met238Arg mutations are associated with early-onset axonal CMT. These findings broaden the mutational spectrum of GARS and also highlight the importance of considering GARS mutations as a disease cause in patients with early-onset neuropathies.

  19. Dual origins for pantellerites, and other puzzles, at Mount Takahe volcano, Marie Byrd Land, West Antarctica

    Science.gov (United States)

    LeMasurier, Wesley; Choi, Sung Hi; Kawachi, Yosuke; Mukasa, Sam; Rogers, Nick

    2018-01-01

    Mt. Takahe is a large, late Quaternary trachyte shield volcano that rises through 2000 + m of the West Antarctic ice sheet. It is composed mostly of ne-trachyte, hy-ol-trachyte, and qz-trachyte flows, with subordinate basanite, intermediate rocks, and pantellerites. All rock types can be adequately modeled by fractional crystallization of basanite - the only basaltic rock exposed here. The ne-trachytes can be explained by a single stage of low-pressure fractionation near the base of the upper crust. Models of oversaturated rocks require a period of evolution at a depth of 35 km, below the stability field of plagioclase, where fractionation of kaersutite and associated high pressure minerals will yield silica oversaturated residual magmas. This is then followed by a period of fractionation at a depth of 3 km, where peralkalinity and Fe-enrichment are acquired. Pantellerite compositions span virtually the entire spectrum of peralkalinity, Fe-enrichment, LILE-enrichment, and SiO2 values, and seem to represent a range of residence times in upper crustal vs., upper mantle magma chambers. Mt. Takahe is unusual among Marie Byrd Land volcanoes for its geochemical anomalies. These include the lowest 143Nd/144Nd ratios in West Antarctica, and unusually high but unpredictable Ba values. These anomalies are believed to originate in a pre-85 Ma subduction mélange at the base of the lithosphere, which seems to be the source of Mt. Takahe basaltic rocks.

  20. The Modular Assessment of Risk for Imminent Suicide (MARIS): A proof of concept for a multi-informant tool for evaluation of short-term suicide risk.

    Science.gov (United States)

    Hawes, Mariah; Yaseen, Zimri; Briggs, Jessica; Galynker, Igor

    2017-01-01

    To date, no diagnostic tool has demonstrated clinical value for the assessment of short-term suicide risk among high-risk individuals. To this end we have developed the Modular Assessment of Risk for Imminent Suicide (MARIS), a modular patient and clinician informed risk evaluation instrument. Here we assess its predictive validity for suicidal behavior (SB) in psychiatric patients following discharge from an inpatient unit. The MARIS and a psychological test battery were administered to 136 adult psychiatric patients hospitalized for high risk of suicide. Eighty-six participants had complete data at discharge and 59 (69.8%) were reached for follow-up. Logistic regressions were used to assess the predictive validity of the MARIS for SB over the 4-8weeks following hospital discharge and its incremental predictive validity over standard risk factors. Patients who exhibited SB in the period between initial assessment and follow-up had significantly higher MARIS scores. ROC analysis indicated good sensitivity and specificity of MARIS in identifying risk (OR=19). Further, MARIS total score significantly improved predictive validity by the standard risk factors when added to a model comprising global depression severity, hopelessness, and lifetime number of suicide attempts, and was the only factor that approached independent significance. The MARIS appears to be a practical and effective tool for detecting short-term suicide risk following hospital discharge, supporting the validity of modular multi-informant approach to suicide risk evaluation. Replication of these findings and further investigation of the applications of such an approach are warranted. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Tectonic conditions of hydrothermal polymetallic vein-type mineralization, Sainte Marie-aux-Mines, France

    Science.gov (United States)

    Hafeznia, Y.; Bourlange, S.; Ohnenstetter, M.

    2012-04-01

    The Sainte-Marie-aux-Mines (SMM) mines host one of the most famous and oldest silver deposits in Europe. The SMM district is located in the central part of the Vosges mountains, France, within gneiss and granites of the Moldanubian zone. The SMM district includes the Neuenberg E-W vein-type Cu-Ag-As/Pb-Zn deposit and the Altenberg N-S vein-type Pb-Zn-Ag deposit. Deposition of the SMM hydrothermal mineralization occurred under a brittle tectonic regime that might be connected to neo-Variscan and/or post-Variscan tectonics, in a similar way as the polymetallic vein deposits of the Black Forest, Germany. A structural study was done in the Neuenberg area, in the vicinity of the Saint-Jacques vein, and within the Gabe Gottes mine, considering the orientation, extent, chronology and density of faults as well as the nature of the infilling minerals. In the Gabe-Gottes mine, the Saint-Jacques vein comprises multiple successive, sub-parallel subvertical veinlets with gangue minerals, mostly carbonates and quartz, and metal-bearing phases, sulfides and sulfosalts. The veinlets are 2 to 50 cm thick and strike N80° to N110°, the earlier veins slightly dipping towards the north, and the latest one, to the south. Seven systems of faults were identified, which may be classified into three major groups formed respectively before, during and after the main stage of ore deposition: a) Pre-mineralization faults - These consist of sinistral NE-SW strike-slip faults, and NW-SE and NE-SW steeply dipping normal faults. These could be related to Carboniferous events considering their relationships with the granitoid intrusives present in the mine area (Brézouard leucogranite ~329 Ma), and the extensional tectonics developed during exhumation processes. b) Faults associated with the main ore-deposition - These faults could be related to late-Hercynian processes from compressional to extensional tectonic regimes. Mineralization controlling faults consist of dextral and sinistral E

  2. Adoration of Virgin Mary Attended by Two St. Johns in Wawel Cathedral Collection

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    Magdalena Piwocka

    2004-12-01

    Full Text Available There is a canvas (98,5 x 222,5cm in the Wawel Cathedral that is not connected with any existing or historically documented altars inside the church (il. 1-3. Owing to its shape it has so far been considered to have been a predella, which - taking into account its size and proportions - seems rather unlikely. It may have been the top of the middle part of a retable, possibly in an altar dedicated to the two St. Johns. The painting presents the Virgin Mary with the Child seated under a canopy, attended by the two Saints, adored by kneeling angels with censers in their hands. A graphic model of the scene has been found; it is an engraving by Jan Sadeler (1550-1600 based on a design by Hans von Aachen (1552-1615, released in Munich in 1589 (il. 4. In Albertina, in Vienna, a working copy of the graphic made by Hans von Aachen has been preserved (il. 5 as well as a composition sketch by the same artist at the Herzog Anton Ulrich-Museum in Braunschweig. An inscription on the drawing from 1589 reads: POENA ET PROEMIVM; there are also quotations from psalms and a dedication to Phillip Wilhelm (1576-1598, bishop of Regenzburg in 1589, later cardinal (1596, son of a Bavarian ruler Wilhelm V Wittelsbach (1548-1626. The young hierarch got it in the year of his consecration as a bishop. A pendant to it is the plate by Jan Sadeler of 1590, after Peter Candid (1548-1628, which was dedicated to Phillip Wilhelm’s younger brother - Ferdinand (1577-1650, later bishop of Cologne. The engraving also shows St. Mary with the Child in the company of St. Stephen and St. Laurence. Both works coincide with the artistic activity of Jan Sadeler and Hans von Achen in Munich, where they were summoned by Wilhelm V, and represent strictly planned art created for his court. Another painted version of Sadeler’s engraving was found in a Polish private collection. This is a small, good painting on panel, faithfully reproducing physiognomy and inscriptions known from the

  3. Sister Mary Joseph's nodule as a presenting sign of internal malignancy.

    Science.gov (United States)

    Dodiuk-Gad, Roni; Ziv, Michael; Loven, David; Schafer, Jan; Shani-Adir, Ayelet; Dyachenko, Pavel; Rozenman, Dganit

    2006-01-01

    CASE 1: A 64-year-old, otherwise healthy woman was referred to the surgery clinic for a presumed umbilical hernia. On physical examination, a cutaneous nodule was noted on the umbilical region and the patient was referred to the dermatology clinic. The patient was reexamined and an erythematous nodule was observed in the umbilicus measuring 2.5 cm in diameter. The patient denied pain, change in bowel habits, or weight loss. There were no other abdominal masses, no sign of ascites, and no regional lymphadenopathy. A skin biopsy from the nodule showed mucinous adenocarcinoma. Immunohistochemical staining was positive for carcinoembryonic antigen, and negative for cytokeratin (CK)7 and CK20. These results were consistent with a Sister Mary Joseph's nodule and led to the diagnosis of an occult colon carcinoma. The patient had no risk factors for colorectal carcinoma. The patient underwent surgery in another hospital, and died 3 months after the initial diagnosis of Sister Mary Joseph's nodule. CASE 2: A 73-year-old woman was referred to the dermatology clinic for evaluation of a painful, ulcerated, 3-cm lesion in the umbilicus (Figure 1). She was otherwise asymptomatic. A skin biopsy showed neoplastic glandular cells infiltrating among collagen bundles (Figure 2). Stainings for mucin and for CK7 were positive, while staining for CK20 was negative. An abdominopelvic CT scan demonstrated a 3.5-cm space-occupying lesion in the liver. Results of gastroscopy, colonoscopy, chest computed tomographic (CT) scan, and mammography were normal. Serum levels of the tumor-associated protein CA125 were elevated to 164 units, while those of CA 19-9 and carcinoembryonic antigen were within normal range. A gynecologic examination and a transvaginal ultrasound were normal. The patient had no personal or family history of any malignancy or any risk factors for developing a carcinoma. The patient was scheduled for a palliative resection of the umbilical nodule, combined with a laparoscopic

  4. Results of Studying of the Stone Age Period of the Mari Volga Region

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    Nikitin Valeriy V.

    2017-09-01

    Full Text Available The article presents the results of 60-year activity of the Mari Archaeological Expedition established by A. Kh. Khalikov in the middle of the previous century at Russkoye-Lugovoye II site. A total of 214 sites of the Mesolithic period have been discovered. The remains of 24 dwellings have been studied by excavations. The obtained data indicate a settled lifestyle of the Mesolithic communities, and a unique selection of settler implements has been established. Three cultural formation of the Neolithic period have been identified. The early Neolithic is represented by the complexes of 40 dwellings with spindle ornamented (forest-steppe type of ceramics. The originality of this dishware with flat bottoms and spindle ornamentation allowed the author to identify an individual culture. The second culture is genetically related to the Volga-Oka tribes which manufactured ceramics with comb and pit ornamentation. A total of 8 dwellings have been studied during excavations. The discovered material culture is similar to that of Balakhnino tribes from the Volga-Oka interfluve. The culture of settlements with Volga-Kama traditions is represented in the region by the remains of 3 dwellings of the developed Neolithic period. The Middle Volga version of the Volosovo culture existed in the area between the Stone and Metal Ages. The remains of 70 dwellings have been excavated. The uniqueness of the material complexes allowed the author to identify the original culture of the territory (within the Volosovo historical and cultural community. This culture originated in the Neolithic period and ceased to exist with the arrival of the Balanovo population skilled in domestic cattle breeding and metallurgy.

  5. Peer Review Evaluation Process of Marie Curie Actions under EU's Seventh Framework Programme for Research.

    Science.gov (United States)

    Pina, David G; Hren, Darko; Marušić, Ana

    2015-01-01

    We analysed the peer review of grant proposals under Marie Curie Actions, a major EU research funding instrument, which involves two steps: an independent assessment (Individual Evaluation Report, IER) performed remotely by 3 raters, and a consensus opinion reached during a meeting by the same raters (Consensus Report, CR). For 24,897 proposals evaluated from 2007 to 2013, the association between average IER and CR scores was very high across different panels, grant calls and years. Median average deviation (AD) index, used as a measure of inter-rater agreement, was 5.4 points on a 0-100 scale (interquartile range 3.4-8.3), overall, demonstrating a good general agreement among raters. For proposals where one rater disagreed with the other two raters (n=1424; 5.7%), or where all 3 raters disagreed (n=2075; 8.3%), the average IER and CR scores were still highly associated. Disagreement was more frequent for proposals from Economics/Social Sciences and Humanities panels. Greater disagreement was observed for proposals with lower average IER scores. CR scores for proposals with initial disagreement were also significantly lower. Proposals with a large absolute difference between the average IER and CR scores (≥10 points; n=368, 1.5%) generally had lower CR scores. An inter-correlation matrix of individual raters' scores of evaluation criteria of proposals indicated that these scores were, in general, a reflection of raters' overall scores. Our analysis demonstrated a good internal consistency and general high agreement among raters. Consensus meetings appear to be relevant for particular panels and subsets of proposals with large differences among raters' scores.

  6. Sleep pattern in Charcot-Marie-Tooth disease type 2: report of family case series.

    Science.gov (United States)

    Souza, Cynthia C; Hirotsu, Camila; Neves, Eduardo L A; Santos, Lidiane C L; Costa, Iandra M P F; Garcez, Catarina A; Nunes, Paula S; Antunes, Adriano

    2015-03-15

    Charcot-Marie-Tooth (CMT) disease is the most prevalent hereditary motor and sensory polyneuropathy, and a condition in which sleep has rarely been studied, particularly in relation to the type 2 (CMT2). Thus, we aimed to characterize the sleep patterns of a family affected by CMT2 disease. Sixteen volunteers with CMT2 from the same multigenerational family agreed to participate in the study (refusal rate = 31%). All participants answered sleep questionnaires and came to the sleep laboratory to perform a diagnostic polysomnography (PSG). Clinical manifestation and severity of the disease were also evaluated. 56% of the sample were male and 44% female, with a mean age of 32 ± 17 years, of normal weight (body mass index 21 ± 3 kg/m(2)); 64% presented moderate to severe CMT2. Regarding subjective sleep, 31% had excessive daytime sleepiness and 75% reported poor sleep quality. The PSG results revealed that CMT2 patients had an increase in stage N3 and a reduction in REM sleep, in addition to a high arousal index. Although 81% of the sample were snorers, only 13% had an apnea-hypopnea index (AHI) > 5. However, a positive correlation was found between the severity of disease and the AHI. Taken together, these data show that CMT2 disease is characterized by important changes in sleep architecture, probably due to sleep fragmentation. Although these alterations may worsen with disease severity, it seems that they are not related to sleep breathing or movement disorders. © 2014 American Academy of Sleep Medicine.

  7. Balance and muscle power of children with Charcot-Marie-Tooth

    Directory of Open Access Journals (Sweden)

    Tais R. Silva

    2014-08-01

    Full Text Available BACKGROUND: In certain diseases, functional constraints establish a greater relationship with muscle power than muscle strength. However, in hereditary peripheral polyneuropathies, no such relationship was found in the literature. OBJECTIVE: In children with Charcot-Marie-Tooth (CMT, to identify the impact of muscle strength and range of movement on the static/dynamic balance and standing long jump based on quantitative and functional variables. METHOD: The study analyzed 19 participants aged between 6 and 16 years, of both genders and with clinical diagnoses of CMT of different subtypes. Anthropometric data, muscle strength of the lower limbs (hand-held dynamometer, ankle and knee range of movement, balance (Pediatric Balance Scale and standing long jump distance were obtained by standardized procedures. For the statistical analysis, Pearson and Spearman correlation coefficients were used. RESULTS: There was a strong positive correlation between balance and the muscle strength of the right plantar flexors (r=0.61 and dorsiflexors (r=0.59 and a moderate correlation between balance and the muscle strength of inversion (r=0.41 and eversion of the right foot (r=0.44. For the long jump and range of movement, there was a weak positive correlation with right and left plantar flexion (r=0.20 and r=0.12, respectively and left popliteal angle (r=0.25, and a poor negative correlation with left dorsiflexion (r=-0.15. CONCLUSIONS: The data on the patients analyzed suggests that the maintenance of distal muscle strength favors performance during balance tasks, while limitations in the range of movement of the legs seem not to be enough to influence the performance of the horizontal long jump.

  8. Feasibility of no-proppant stimulation to enhance removal of methane from the Mary Lee Coalbed

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, S.W.; Trevits, M.A.

    1980-04-01

    One experimental approach to hydraulic stimulation is to use fluid to propagate fractures but not to incorporate solid proppant material in the design. The elimination of solid material negates problems related to wellbore sand proppant influx and allows better fracture height control since extremely low injection rates can be used. The Mary Lee Coalbed was stimulated using a 53,000 gallon no-proppant treatment at a 1,150 foot deep test well located approximately 1,600 feet in advance of mining. The well produced for 147 days and gas flow rates declined sharply, ceasing when intercepted by mining. Production comparison of the no-proppant test with another test incorporating sand proppant indicates that the 53,000 gallon no-proppant treatment was less effective than the more conventional 21,000 gallon treatment. The results from the no-proppant test indicate that very few roof rock fluid penetrations occurred during the course of hydraulic stimulation. It cannot be determined, however, if sparsity of roof penetration was due to the use of very low injection rates or because roof rock in the physical test area was less jointed and, therefore, less prone to stimulation fluid invasions. Because gas flow results gathered are inconclusive, the application of no-proppant stimulation designs for other than research is not recommended at this time. The lower injection rate approach to fracture height control is, however, theoretically sound and because limiting upward fracture growth in coalbeds may be desirable to future borehole gas drainage activities, no-proppant experiments could be justified on a limited scale.

  9. Molecular analysis of the genes causing recessive demyelinating Charcot-Marie-Tooth disease in Japan.

    Science.gov (United States)

    Hayashi, Makiko; Abe, Akiko; Murakami, Tatsufumi; Yamao, Satoshi; Arai, Hidee; Hattori, Hideji; Iai, Mizue; Watanabe, Kyoko; Oka, Nobuyuki; Chida, Keiji; Kishikawa, Yumiko; Hayasaka, Kiyoshi

    2013-05-01

    Charcot-Marie-Tooth disease (CMT), the most common hereditary neuropathy, has been classified into two types, demyelinating and axonal types. We previously analyzed the genes causing dominant demyelinating CMT in 227 Japanese patients to identify the genetic background, but could not find any mutations in 110 patients. To investigate the frequency of patients with autosomal recessive demyelinating CMT (CMT4) mutations, we analyzed the coding sequence of known causative genes of CMT4 in 103 demyelinating CMT patients, excluding seven patients owing to lack of specimens. We found one patient with a GDAP1 mutation, one patient with an MTMR2 mutation, two patients with SH3TC2/KIAA1985 mutations and three patients with FGD4 mutations. Twelve patients, including five previously detected patients with PRX mutations, were diagnosed as CMT4, accounting for 5.5% of demyelinating CMT. In the patient with GDAP1 mutation, only one mutation inherited from his mother was detected by genomic sequencing. Analysis by reverse transcription polymerase chain reaction using messenger RNA (mRNA) from the patient's leukocytes revealed the absence of transcription from the allele inherited from his father, suggesting the existence of one more mutation leading to a lack or destabilization of mRNA. Most patients carrying CMT4 gene mutations present with early-onset and slowly progressive symptoms, which may be associated with the function of mutants. We could not identify the disease-causing gene in 96 patients (about 45%). Further studies including studies with next-generation sequencers will be required to identify the causative gene in Japanese CMT.

  10. Balance and muscle power of children with Charcot-Marie-Tooth.

    Science.gov (United States)

    Silva, Tais R; Testa, Amanda; Baptista, Cyntia R J A; Marques, Wilson; Mattiello-Sverzut, Ana C

    2014-01-01

    In certain diseases, functional constraints establish a greater relationship with muscle power than muscle strength. However, in hereditary peripheral polyneuropathies, no such relationship was found in the literature. In children with Charcot-Marie-Tooth (CMT), to identify the impact of muscle strength and range of movement on the static/dynamic balance and standing long jump based on quantitative and functional variables. The study analyzed 19 participants aged between 6 and 16 years, of both genders and with clinical diagnoses of CMT of different subtypes. Anthropometric data, muscle strength of the lower limbs (hand-held dynamometer), ankle and knee range of movement, balance (Pediatric Balance Scale) and standing long jump distance were obtained by standardized procedures. For the statistical analysis, Pearson and Spearman correlation coefficients were used. There was a strong positive correlation between balance and the muscle strength of the right plantar flexors (r=0.61) and dorsiflexors (r=0.59) and a moderate correlation between balance and the muscle strength of inversion (r=0.41) and eversion of the right foot (r=0.44). For the long jump and range of movement, there was a weak positive correlation with right and left plantar flexion (r=0.20 and r=0.12, respectively) and left popliteal angle (r=0.25), and a poor negative correlation with left dorsiflexion (r=-0.15). The data on the patients analyzed suggests that the maintenance of distal muscle strength favors performance during balance tasks, while limitations in the range of movement of the legs seem not to be enough to influence the performance of the horizontal long jump.

  11. Chemical and biological status of headwater lakes in the Sault Ste. Marie District, Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Kelso, J.R.M.; Love, R.J.; Lipsit, J.H.; Dermott, R.

    1984-01-01

    The fish, benthos, and phytoplankton reflected to varying degrees the acidic status of their aquatic system. Although lakes in the Sault Ste. Marie district range from acidic to well buffered, the link of acidic state to atmospheric acid addition is circumstantial, as historical data is limited. Nevertheless, a significant proportion of lakes in the district are acidic, high in aluminum and lead concentrations, and poorly buffered. Biota in these lakes are to some extent protected by their life style and species tolerance against further change in acidic status. Benthos are notably harbored against changes occurring in the water column by the ability of their microhabitat to counteract changes in lake pH. On the other hand, when behavior or development of the benthos removes them from the sediment, they then are prone to effects of predators, competitors, and lake chemistry. The phytoplankton of these lakes, while responding directly to lake conditions by shifts in community, do not appear to alter dramatically in community composition. Fish, on the other hand, operate much as the benthos with the response to acid state tempered by species tolerance, life style, metabolism of contaminants, and their compensation to changes induced by acidification in other trophic levels. In natural systems, although white sucker are generally more sensitive to low pH than brook trout, difference in life style alters exposure to and uptake of contaminants and may favor existence of white sucker. In total, it seems that although benthos and phytoplankton respond to changes in their habitat, the effect upon fish is more blatant as seen through population success or metabolism of contaminants. 10 figures, 7 tables.

  12. Sexual functioning in women with mild and severe symptoms of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Gargiulo, Paola; Vinci, Paola; Navarro-Cremades, Felipe; Rellini, Alessandra H

    2013-07-01

    Charcot-Marie-Tooth (CMT) disease is one of the most frequently inherited neurological disorders, and while it is known that individuals suffering from this condition have low quality of life, little is known about their sexual function and satisfaction. To describe the functioning on different domains of sexuality in a relatively large sample of women with CMT, provide comparisons between mildly and severely affected patients and between women with the two different types of CMT (demyelinating vs. axonal), and assess the relationship between sexual function and age of onset. Fifty-seven women (age: 18-60 years) were approached in a CMT rehabilitation clinic by a psychologist and administered the Italian version of the McCoy Female Sexuality Questionnaire (MFSQ). Data from 40 patients who had had sexual intercourse in the previous 4 weeks were analyzed. The main outcome measures are the factors MFSQ-SEX and MFSQ-PARTNER, which describe sexual functioning and sexual satisfaction with a partner, respectively. Almost 30% of women did not engage in sexual intercourse with a partner. Overall sexual problems were more prominent in younger women and tended to be lower as age increased: this pattern was different from what was reported in previous studies in comparable samples of healthy Italian women. Severity of CMT was associated with better sexual functioning in the areas of desire, arousal, orgasm, and satisfaction, with women with more severe symptoms reporting greater functioning. Women with more severe CMT symptoms reported more pain during intercourse. Age of CMT onset and type of CMT (demyelinating vs. axonal) were not associated with differences in sexual functioning. Findings point to the importance of including assessment of sexual dysfunction in young women with mild CMT symptoms and the importance of providing sex therapy or counseling to these patients. © 2013 International Society for Sexual Medicine.

  13. La robe et les mortiers. Joseph-Marie de Villespassans, magistrat faux-monnayeur (1713

    Directory of Open Access Journals (Sweden)

    Mathieu Soula

    2011-12-01

    Full Text Available Au début du XVIIIe siècle, un magistrat toulousain, le conseiller de Villepassans, est soupçonné d’être à la tête d’un réseau de faux-monnayeurs. L’affaire est sensible pour le parlement, qui instruit directement l’affaire, car il s’agit de poursuivre l’un de ses membres. Un magistrat faux-monnayeur est en effet une « figure » criminelle qui trouble et pose question. Par contagion, la mauvaise renommée de Villepassans peut atteindre les autres conseillers et porter le discrédit sur une institution qui se définit comme « le vrai vengeur des crimes ». Dans ces conditions, comment le parlement traite-t-il l’affaire, et quelle figure criminelle appose-t-il à Villespassans ? L’étude de ce cas atypique peut ainsi aider à mieux comprendre l’enjeu de la construction d’une identité criminelle.In early 18th century, a magistrate of the parliament of Toulouse, Joseph-Marie de Villespassans, is suspected of being the leader of forgers of money. This case is highly dangerous for the parliament, who’s in charge. The culpability of the magistrate-forger can also touch the others magistrates, and the prestige of the institution to. So, in these conditions, how can the parliament manage this case? I this research, we’re trying to study this atypical case in the way the parliament built the culpability.

  14. Entrevista com Marie Raynal, Redatora chefe da Revista Diversité - França (Tradução. Interview with Marie Raynal, editor of Diversité - France (Translation

    Directory of Open Access Journals (Sweden)

    Abramowicz, Anete

    2009-11-01

    Full Text Available A Revista Eletrônica de Educação teve o privilégio de entrevistar Marie Raynal, que apesar de muitas atividades nos concedeu um tempo para nos responder. Marie Raynal é Responsável pelo Departamento Ville-Ecole-Intégration (Cidade-Escola-Integração em Montrouge, França e Redatora Chefe (rédactrice em chef da Revista Diversité que é um dos únicos periódicos da educação na França que acolhe artigos sobre a diversidade social. Em 2003 foi criado o departamento “Ville & Education” sob a coordenação de Marie Raynal. Este departamento tem por missão acompanhar todos os atores da educação (professores, quadros da educação, coletividades, associações, etc. que tem por encargo - durante e fora do tempo escolar - as crianças e os jovens em situação de fragilidade, especialmente aqueles que vivem nos bairros da política da cidade, àqueles que se destacam por uma educação prioritária, os recém chegados na França e as crianças nômades. No conjunto destas questões, este departamento é considerado como expert nacional. Este departamento possui três revistas e uma carta de informação, entre elas está a revista trimestral em Ciências Sociais, a Diversité.The Revista Eletrônica de Educação (Electronic Journal of Education has the privilege to interview Marie Raynal, which although having many activities, dedicated us time to answer it. Marie Raynal is head of the Département de Ville-Ecole-Intégration (Department of City-School-Integration in Montrouge, France and Chief editor of the journal Diversité, which includes articles on social diversity. In 2003, the department "Ville & Education" is created under the authority of Marie Raynal. Its mission is to accompany all education members (teachers, education managers, communities, associations, etc. that are in charge, during and after school time, children and youth in situations of fragility, including those living in neighborhood of the city policy, those

  15. Comparing methods for estimating larval sea lamprey (Petromyzon marinus) density in the St. Marys River for the purposes of control

    Science.gov (United States)

    Robinson, Jason M.; Wilberg, Michael J.; Adams, Jean V.; Jones, Michael L.

    2015-01-01

    The St. Marys River is a major producer of parasitic sea lampreys (Petromyzon marinus) to Lake Huron making it an important area for larval control. Bayluscide treatments are conducted in areas of high larval density requiring density estimation at fine spatial scales to inform treatment decisions. We evaluated six methods of estimating spatially specific density including the currently used sampling-based estimates, a generalized linear model (GLM) based on mean larval density per plot, a GLM based on larval density per sample, a generalized additive model based on mean larval density per plot, a spatial age-structured population model, and a hybrid approach, which averaged the best performing sampling- and model-based methods. Methods were evaluated based on accuracy in matching independent validation data. Specifically, the methods were evaluated based on their ability to project plot-level larval density, identify high density plots for treatment, and rank plots in order based on density resulting in high numbers of sea lampreys killed per hectare treated. Performance was variable, and no single method outperformed the others for all metrics. Although the sampling-based estimation method and the GLM based on catch data performed adequately for estimating density and identifying high density plots, the hybrid approach was identified as the best method to inform sea lamprey control decisions in the St. Marys River due to its consistent performance. Incorporating model-based approaches should lead to a more efficient and effective treatment program in the St. Marys River and aid in making decisions about the allocation of control resources.

  16. The famine of 1921-1922 and the confiscation of church property (on materials of the Mari region

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    Starikova Elena

    2015-03-01

    Full Text Available Famine 1921–1922 led to the death of thousands of people. The Soviet government used this fact against the Russian Orthodox Church. On the basis of regional sources revealed the true extent of hunger in the Mari region. This event was the reason for the start of the campaign in favor of the confi scation of church property. The study described in detail the main stages of preparation, organization and implementation of this process in the Mari region. The author describes the formation and work of the regional committee for the implementation of the decree of the Central Executive Committee February 23, 1922. The author also describes the procedures canton commissions in individual parishes. The author gives a detailed description of the order of confiscation of church property in the May-June 1922. The study shows the character and content of the documents that were provided to local authorities, describes the procedure of removal of property in the parish, partially installed subsequent fate of the seized property. According to the materials of parishes revealed damage that was done separately taken the community of believers. Statistical data on the withdrawal values in the Mari region are shown in comparison with the general Soviet figures. Analyzing the response of believers to the current policy, the author comes to the conclusion that this campaign has not got wide publicity and generally calm was greeted population of the province. Such a reaction is understandable by severe plight of the population in conditions of famine of the early 1920s. Results of the study allowed the author to explain the circumstances of the campaign. It is rated as blasphemous method of helping the starving population at the expense of inalienable property of the Russian Orthodox Church

  17. Tibialis posterior tendon transfer corrects the foot drop component of cavovarus foot deformity in Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Dreher, T; Wolf, S I; Heitzmann, D; Fremd, C; Klotz, M C; Wenz, W

    2014-03-19

    The foot drop component of cavovarus foot deformity in patients with Charcot-Marie-Tooth disease is commonly treated by tendon transfer to provide substitute foot dorsiflexion or by tenodesis to prevent the foot from dropping. Our goals were to use three-dimensional foot analysis to evaluate the outcome of tibialis posterior tendon transfer to the dorsum of the foot and to investigate whether the transfer works as an active substitution or as a tenodesis. We prospectively studied fourteen patients with Charcot-Marie-Tooth disease and cavovarus foot deformity in whom twenty-three feet were treated with tibialis posterior tendon transfer to correct the foot drop component as part of a foot deformity correction procedure. Five patients underwent unilateral treatment and nine underwent bilateral treatment; only one foot was analyzed in each of the latter patients. Standardized clinical examinations and three-dimensional gait analysis with a special foot model (Heidelberg Foot Measurement Method) were performed before and at a mean of 28.8 months after surgery. The three-dimensional gait analysis revealed significant increases in tibiotalar and foot-tibia dorsiflexion during the swing phase after surgery. These increases were accompanied by a significant reduction in maximum plantar flexion at the stance-swing transition but without a reduction in active range of motion. Passive ankle dorsiflexion measured in knee flexion and extension increased significantly without any relevant decrease in passive plantar flexion. The AOFAS (American Orthopaedic Foot & Ankle Society) score improved significantly. Tibialis posterior tendon transfer was effective at correcting the foot drop component of cavovarus foot deformity in patients with Charcot-Marie-Tooth disease, with the transfer apparently working as an active substitution. Although passive plantar flexion was not limited after surgery, active plantar flexion at push-off was significantly reduced and it is unknown whether

  18. Primary peritoneal carcinoma presenting as a Sister Mary Joseph's nodule: A case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Robyn L. Schickler

    2016-08-01

    Full Text Available Sister Mary Joseph's nodule is sometimes the first sign of an internal malignancy, including gastrointestinal, gynecological, or malignancy of unknown primary. It is rarely the sole presentation of a primary peritoneal cancer. In this report, we present the case of a 70-year-old female with umbilical drainage and a computed tomography scan consistent with solitary umbilical nodule. Excision of the nodule revealed adenocarcinoma of likely müllerian origin. Surgical staging did not show any evidence of malignancy with the exception of pelvic washings. She was considered to have primary peritoneal adenocarcinoma and was treated with adjuvant chemotherapy.

  19. Harvey Cushing and pituitary Case Number 3 (Mary D.): the origin of this most baffling problem in neurosurgery.

    Science.gov (United States)

    Pascual, José María; Prieto, Ruth

    2016-07-01

    From the very beginning of his career, Harvey Williams Cushing (1869-1939) harbored a deep interest in a complex group of neoplasms that usually developed at the infundibulum. These were initially known as "interpeduncular" or "suprasellar" cysts. Cushing introduced the term "craniopharyngioma" for these lesions, which he believed represented one of the most baffling problems faced by neurosurgeons. The patient who most influenced Cushing's thinking was a 16-year-old seamstress named "Mary D.," whom he attended in December 1901, exactly the same month that Alfred Fröhlich published his seminal article describing an adiposogenital syndrome in a young boy with a pituitary cyst. Both Cushing's and Fröhlich's patients showed similar symptoms caused by the same type of tumor. Notably, Cushing and Fröhlich had met one another and became good friends in Liverpool the summer before these events took place. Their fortunate relationship led Cushing to realize that Fröhlich's syndrome represented a state of hypopituitarism and provided a useful method of diagnosing interpeduncular cysts. It is noteworthy that Cushing's very first neurosurgical procedure on a pituitary tumor was performed in the case of Mary D.'s "interpeduncular cyst," on February 21, 1902. Cushing failed to remove this lesion, which was later found during the patient's autopsy. This case was documented as Pituitary Case Number 3 in Cushing's masterpiece, The Pituitary Body and Its Disorders, published in 1912. This tumor was considered "a teratoma"; however, multiple sources of evidence suggest that this lesion actually corresponded to an adamantinomatous craniopharyngioma. Unfortunately, the pathological specimens of this lesion were misplaced, and this prompted Cushing's decision to retain all specimens and documents of the cases he would operate on throughout his career. Accordingly, Mary D.'s case crystallized the genesis of the Cushing Brain Tumor Registry, one of Cushing's major legacies to

  20. Une créatrice sociale à Marseille : Marie Oddo (1868-1955)

    OpenAIRE

    Richard, Éliane

    2017-01-01

    Comme Simone Sédan et Germaine Poinso-Chapuis, auxquelles Yvonne Knibiehler a consacré livre, article et biographies, Marie Oddo est une Marseillaise dont les historiens du service social se doivent de conserver la mémoire. « Chrétienne fervente, femme d’autorité, son engagement dans la création et l’administration d’œuvres sociales a fait d’elle une personnalité incontournable », toujours au service des femmes. Elle a 30 ans à la naissance de Simone Baudry et 33 à celle de Germaine Chapuis. ...

  1. On the symbol error rate of M-ary MPSK over generalized fading channels with additive Laplacian noise

    KAUST Repository

    Soury, Hamza

    2014-06-01

    This paper considers the symbol error rate of M-ary phase shift keying (MPSK) constellations over extended Generalized-K fading with Laplacian noise and using a minimum distance detector. A generic closed form expression of the conditional and the average probability of error is obtained and simplified in terms of the Fox\\'s H function. More simplifications to well known functions for some special cases of fading are also presented. Finally, the mathematical formalism is validated with some numerical results examples done by computer based simulations. © 2014 IEEE.

  2. On the Symbol Error Rate of M-ary MPSK over Generalized Fading Channels with Additive Laplacian Noise

    KAUST Repository

    Soury, Hamza

    2015-01-07

    This work considers the symbol error rate of M-ary phase shift keying (MPSK) constellations over extended Generalized-K fading with Laplacian noise and using a minimum distance detector. A generic closed form expression of the conditional and the average probability of error is obtained and simplified in terms of the Fox’s H function. More simplifications to well known functions for some special cases of fading are also presented. Finally, the mathematical formalism is validated with some numerical results examples done by computer based simulations [1].

  3. The wild heart of a wild land. Tra le Alpi albanesi sulle orme di Mary Edith Durham

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    M. Genesin

    2012-08-01

    Full Text Available ENIn 2007 we decided to follow the same route through northern Albania which was covered almost 100 years ago by the victorian traveller Mary Edith Durham, author of the books High Albania and Some Tribal Origins, Laws and Customs of the Balkans. The journey described in High Albania was the culmination of seven years of regular Balkan travels during which she was rewarded with insights into north Albanian life denied to all previous travellers. Unlike her other expeditions in the Balkans, her journey in northern Albania was an existential experience which deeply affected Durham’s perception of the tribespeople’s world and marked a turning point in her life. In the second part of the article some ethnographical aspects which were pointed out by Durham and are still alive in those regions are dealt with. Keywords: Balkan Studies; Cultural Studies; Ethnography; Mary Edith Durham; Albania  ITNel 2007 abbiamo deciso di organizzare una spedizione a carattere linguistico e etnogrfico nell’Albania settentrionale sulle orme dell’itinerario percorso quasi 100 anni prima dalla viaggiatrice vittoriana Mary Edith Durham, autrice dei volumi High Albania e Some Tribal Origins, Laws and Customs of the Balkans. L’itinerario descritto in High Albania coronò setti lunghi anni di esplorazioni balcaniche nel corso delle quali l’autrice riuscì a penetrare nella vita della popolazione locale, un importante esperienza che era invece mancata a tutti i precedenti viaggiatori. A differenza dagli altri viaggi precedenti nei balcani, quello nell’Albania settentrionale costituì un esperienza esistenziale che segnò profondamente la percezione della Durham del mondo delle alpi albanesi e rappresentò una svolta nella sua vita. Nella seconda parte dell’articolo sono illustrati alcuni fenomeni di carattere etnografico che furono rilevati dalla Durham e che, con nostra grande sorpresa, abbiamo potuto riscontrare sul campo nel corso della spedizione.

  4. Sister mary joseph′s nodule: A case of umbilical cutaneous metastasis with signet ring cell histology

    Directory of Open Access Journals (Sweden)

    Zadeh Valid

    2009-01-01

    Full Text Available The metastasis of a visceral malignancy to the umbilicus is known as "Sister Mary Joseph′s nodule". It is a rare clinical sign indicating advanced, metastasizing intraabdominal cancer. We report a 50-year-old man who developed metastatic skin cancer in the form of semicircular indurated plaque on top of which was a firm mobile rounded nodule at the umbilical area. Histopathological examination demonstrated diastase-resistant periodic acid-Schiff and mucicarmine positive signet ring cells, suggesting gastric carcinoma. Immunohistochemical staining showed that these cells were positive for cytokeratins and epithelial membrane antigen, suggesting epithelial origin.

  5. The Significance, for Readers in the Twenty-first Century, of the Character of Safie in Mary Shelley's Frankestein

    Directory of Open Access Journals (Sweden)

    Esther Katheu Mbithi

    2017-02-01

    Full Text Available The Significance, for Readers in the Twenty-first century, of the Character of Safie in Mary Shelley's Frankenstein. Abstract: This paper presents a critical look at one of the characters in Mary Shelley’s Frankenstein, Safie, through the lenses of a female African scholar in the twenty-first century. A close look at the narrative structure leads to the gradual peeling off of the first two layers, to the core of the narration. The paper looks keenly at a minor character in this core, in the light of feminist literary criticism and against the concept of globalisation. The analysis of the character of Safie, carried out in full consciousness of the fact that Frankenstein was written two hundred years ago, involves a look at the words used to describe her; comparison between her and other characters, particularly other female characters; as well as a general overview of her circumstances and how she reacts in response to them. Keywords: literature, English, Gothic, Romanticism, feminism, Frankestein. // El significado del personaje de Safie en Frankestein, de Mary Shelley, para los lectores del siglo XXI. Resumen: Este artículo estudia críticamente a Safie, uno de los personajes de Frankestein de Mary Shelley, desde la perspectiva de una investigadora africana. Un examen atento de la estructura narrativa de la novela permite despojarla de sus dos capas exteriores, para alcanzar el núcleo de la narración. Este trabajo examina un personaje secundario de este núcleo a la luz de la crítica literaria feminista y en contra del concepto de globalización. El análisis del personaje de Safie, realizado con plena conciencia del hecho de que Frankestein fue escrito hace doscientos años, exige el examen de los términos usados para describirla; la comparación entre ella y otros personajes, especialmente otros personajes femeninos; así como una contextualización de sus circunstancias y de cómo Safie reacciona ante ellas. Palabras clave

  6. Misunderstanding of foot drop in a patient with charcot-marie-tooth disease and lumbar disk herniation.

    Science.gov (United States)

    Han, Youngmin; Kim, Kyoung-Tae; Cho, Dae-Chul; Sung, Joo-Kyung

    2015-04-01

    We report the case of 57-year-old woman diagnosed with Charcot-Marie-Tooth (CMT) disease and lumbar disk herniation (LDH). She had left leg weakness and foot numbness, foot deformity (muscle atrophy, high arch, and clawed toes). The lumbar spine MRI showed LDH at L4-5. Additionally, electrophysiology results were consistent with chronic peripheral motor-sensory polyneuropathy (axonopathy). In genetic testing, 17p11.2-p12 duplication/deletions characteristic of CMT disease were observed. We confirmed the patient's diagnosis as CMT disease and used conservative treatment.

  7. New data on Pleistocene and Holocene herpetofauna of Marie Galante (Blanchard Cave, Guadeloupe Islands, French West Indies): Insular faunal turnover and human impact

    Science.gov (United States)

    Bailon, S.; Bochaton, C.; Lenoble, A.

    2015-11-01

    This work presents the herpetofaunal remains collected from Blanchard Cave (Marie-Galante, Guadeloupe Archipelago). This site has yielded the oldest stratigraphic layers (around 40,000 BP) of the island, along with data concerning the herpetofaunal biodiversity of the island from the Late Pleistocene to pre-Columbian and modern times. The study of these fossil remains reveals the presence of at least 11 amphibian and squamata taxa (Eleutherodactylus cf. martinicensis, Iguana sp., Anolis ferreus, Leiocephalus cf. cuneus, Thecadactylus cf. rapicauda, cf. Capitellum mariagalantae, Ameiva sp., cf. Antillotyphlops, Boa sp., Alsophis sp. and Colubridae sp. 2) during the Late Pleistocene and Holocene on Marie-Galante Island and provides new evidence concerning extinction times and the introduced or native status of taxa. This study also reveals that this bone assemblage is the result of diverse accumulation processes and provides new morphological data on the past herpetofauna of Marie-Galante.

  8. Mariátegui e a questão da educação no Peru Mariátegui and the issue of education in Peru

    Directory of Open Access Journals (Sweden)

    Luiz Bernardo Pericás

    2006-01-01

    Full Text Available Este artigo discute a participação do jornalista e pensador político marxista José Carlos Mariátegui nos debates que ocorreram no Peru na década de 1920. Os temas das discussões analisadas no presente texto são: as Universidades Populares; a cultura nacional; as bibliotecas; a publicação de livros, revistas e jornais; o movimento estudantil; e o papel do Estado, dos indígenas e dos trabalhadores urbanos e rurais na elaboração de uma política de educação pública abrangente para os setores mais pobres da população daquele país.This article deals with the participation of the journalist and Marxist political thinker José Carlos Mariátegui in the debates that occurred in Peru in the 1920’s about the Popular Universities; the national culture; the libraries; the publication of books, magazines and newspapers; the students’ movement; the role of the State, the indigenous peoples and the urban and rural workers in the elaboration of a broad Public Education for the poorest strata of the population of that country.

  9. Body composition and its association with physical performance, quality of life, and clinical indictors in Charcot-Marie-Tooth disease: a pilot study.

    Science.gov (United States)

    Hackett, Daniel; Roberts-Clarke, Daniel; Jain, Nidhi; Mavros, Yorgi; Wilson, Guy C; Halaki, Mark; Burns, Joshua; Nicholson, Garth; Fiatarone Singh, Maria; Fornusek, Che

    2017-11-02

    To investigate whether the amount and distribution of lean body mass and fat mass is associated with disease severity in adults with Charcot-Marie Tooth. Ten participants (age 46 ± 13 y, height 1.7 ± 0.1 m, and body mass 77 ± 17 kg) with Charcot-Marie Tooth disease were involved in this study. Participants were evaluated for quality of life, falls efficacy, balance, mobility, muscle strength, and power. Body composition was measured using dual energy x-ray absorptiometry. Statistical analyses were conducted on subsets of all participants. Better static balance was associated with higher lean body mass of the lower leg (r = 0.73, p = 0.03), while superior leg press strength and power was associated with greater lean body mass of the leg and lower leg (r ≥ 0.80, p ≤ 0.01). Faster habitual walking speed and enhanced quality of life was associated with lower fat mass of several regions. Our study seems to suggest that assessing of body composition could assist with monitoring of disease progression in people with Charcot-Marie Tooth; however these findings need to be substantiated in a larger cohort. Implications for Rehabilitation Higher lean body mass and lower fat mass of the legs is associated with better physical performances in people with Charcot-Marie-Tooth disease. Lower fat mass is related to greater quality of life and reduced clinical symptoms in people with Charcot-Marie-Tooth disease. Optimising favorable body composition profiles (higher lean body mass and lower fat mass) in people with Charcot-Marie-Tooth disease may be highly clinically relevant.

  10. Vliv značky Mary Kay na kupní chování zákazníků

    OpenAIRE

    Teplá, Zuzana

    2015-01-01

    The diploma thesis deals with the analysis of the influence of Mary Kay brand on purchase behavior of customers B2C markets thanks to the model customer-based brand equity and the model ColourMind using colour-word association method CWAT. Its aim is to evaluate perception of the brand and factors influencing behavior of customers. Theoretical part is focused on B2C markets, brand politics, customers and their attitude to shopping. Practical part deals with identification of Mary Kay company,...

  11. MaRIE 1.0: The Matter-Radiation Interactions in Extremes Project, and the Challenge of Dynamic Mesoscale Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Barber, John L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kober, Edward Martin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lookman, Turab [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sandberg, Richard L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Shlachter, Jack S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sheffield, Richard L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-02-23

    The Matter-Radiation Interactions in Extremes project will build the experimental facility for the time-dependent control of dynamic material performance. An x-ray free electron laser at up to 42-keV fundamental energy and with photon pulses down to sub-nanosecond spacing, MaRIE 1.0 is designed to meet the challenges of time-dependent mesoscale materials science. Those challenges will be outlined, the techniques of coherent diffractive imaging and dynamic polycrystalline diffraction described, and the resulting requirements defined for a coherent x-ray source. The talk concludes with the role of the MaRIE project and science in the future.

  12. Gastronomía típica Margariteña como atractivo turístico del Municipio Mariño Estado Nueva Esparta

    Directory of Open Access Journals (Sweden)

    Medina, María

    2008-04-01

    Full Text Available The typical margariteñan gastronomy, its elements: restaurants, authors, dishes and promotion as a tourism attraction at the Municipio Mariño is characterized. Recommendations for its improvement are presented. Tourism and gastronomy are the theoretical grounds and its importance for the tourism industry. A descriptive and field methodology was used. Today, there is a lack of information, promo-tion and improvement of the typical margariteñan gastronomy as a tourism attraction at the Municipio Mariño due to the lack of its knowledge in addition to the modification that restaurants of the Municipio are doing with the original recipes, are concluded

  13. VISIONARY THINKER: LEADERSHIP AND MANAGEMENT IN WORKS OF MARY P. FOLLETT – LONG-TERM PERSPECTIVE IN THE COMPANIES OF THE REPUBLIC OF SERBIA

    Directory of Open Access Journals (Sweden)

    Srdjan Nikezic

    2014-06-01

    Full Text Available In her lectures, Mary P. Follett pointed to key moments of leadership, management, group membership, coordination and participation as relevant elements for the exploration of human relations that are of interest today in the same way as they were eighty years ago. Model of thinking applied by Mary P. Follett is deeply linked to current strong needs for the creation of leadership and management professions that are linked to changes and long term strategic goals of big companies and world economy as a whole.

  14. Birds, Messages and Messengers in the Lais of Marie de France: “Matière de Bretagne” and/or Troubadour Lyrics

    Directory of Open Access Journals (Sweden)

    Dolgorukova Natalia Mikhailovna

    2013-11-01

    Full Text Available The article presents the three of Marie de France’s lais in which birds, messages and messengers play an important role. The influence of “Matière de Bretagne” over these lais is obvious. However, troubadours’ lyrics have an influence on Marie de France’s Lais as much as “Matière de Bretagne”. Very often themes from “Matière de Bretagne” and themes from Occitan poetry overlap each other forming a bizarre fusion in her lais.

  15. Biblical motives from the Book of Joshua and Book of Judges in the Hours about the Immaculate Conception of the Most Holy Virgin Mary

    OpenAIRE

    Krystian Ziaja

    2010-01-01

    The aim of the article is better understanding of the Hours concerning the Immaculate Conception of the Most Holy Virgin Mary. Following motives from the books of Joshua and Judges were taken into consideration: The light from Gabaon (Joshua 10, 10–13), Gedeon’s fleece (Judges 6, 36–40), Samson’s honeycomb (Judges 14, 1–11). After the discussion of the above mentioned three texts we may ascertain that the author of Hours about the Immaculate Conception of the Most Holy Virgin Mary with accura...

  16. The Use of MARIE CPU Simulator in Computer Architecture Course: A Case Study of Student's Perception of Learning and Performance

    Directory of Open Access Journals (Sweden)

    Jorge Fernando Maxnuck Soares

    2016-12-01

    Full Text Available This study aims to show results of employing a case study in the use of Active Learning Practices in the Computer Architecture discipline. The practice in question is the use of Marie® CPU Simulator as a practical tool in the development of the course. The methodology of the study aims to verify whether the use of Marie® CPU Simulator contributes to improving the learning of the Computer Architecture discipline, especially whether it provides a better understanding of the parts that integrate the architecture of a given CPU, with an explanation of the function of the parts, and their interrelationship. This study shows the first results of a more comprehensive study on the use of active learning practices, using software in high-tech disciplines of an information system course. The secondary purpose is to show the application of the case study as a methodology outside the usual areas, such as: medicine, psychology and business administration. This study seeks to show the advantages and limitations found, highlighting its potential in the academic field in relation to the use of active learning practices in lessons of technical subjects, such as Computer Architecture, without losing scientific thoroughness in data processing and in the research methodology.

  17. Una mirada sobre otra: el Gramsci que conoció Mariátegui A regard over the other

    Directory of Open Access Journals (Sweden)

    Fernanda Beigel

    2007-05-01

    Full Text Available Entre los principales objetivos del trabajo, nos proponemos precisar el alcance – hasta ahora exagerado – de la vinculación entre el pensamiento de Mariátegui y Gramsci. Para ello realizamos una distinción simple (prácticamente obvia en el campo de estudios gramscianos, pero no tan evidente en los estudios mariateguianos entre dos corrientes de pensamiento y acción que están íntimamente vinculadas pero deben ser diferenciadas en la práctica: la experiencia ordinovista y la cosmovisión gramsciana. Palabras clave: Política. Cultura. Empresa. Marxismo. Herança teórica. Among the many goals of this paper, the main one was to say that there is really a bond between the ideas of Mariátegui and Gramsci, so far exaggerated. In order to do it, there is exposition of the simple distinction (absolutely obvious in the gramscian studies but not so evident among the mariateguians between the views of thought and action, intimately connected but so different in practice: the Gramsci´s ordinovistic experience and conception of the world. Keywords: Politics. Culture. Enterprise. Marxism. Theoretical heritage.

  18. Technology Risk Mitigation Research and Development for the Matter-Radiation Interactions in Extremes (MaRIE) Project

    Science.gov (United States)

    Barnes, Cris W.; Fernández, Juan; Hartsfield, Thomas; Sandberg, Richard; Sheffield, Richard; Tapia, John P.; Wang, Zhehui

    2017-06-01

    NNSA does not have a capability to understand and test the response of materials and conditions necessary to determine the linkages between microstructure of materials and performance in extreme weapons-relevant environments. Required is an x-ray source, coherent to optimize imaging capability, brilliant and high repetition-rate to address all relevant time scales, and with high enough energy to see into and through the amount of material in the middle or mesoscale where microstructure determines materials response. The Department of Energy has determined there is a mission need for a MaRIE Project to deliver this capability. There are risks to the Project to successfully deliver all the technology needed to provide the capability for the mission need and to use those photons to control the time-dependent production and performance of materials. The present technology risk mitigation activities for the MaRIE project are: developing ultrafast high-energy x-ray detectors, combining the data from several imaging probes to obtain multi-dimensional information about the sample, and developing techniques for bulk dynamic measurements of temperature. This talk will describe these efforts and other critical technology elements requiring future investment by the project.

  19. In search of the Holy Presence of the Blessed Mary in Tolkien’s Middle-earth

    Directory of Open Access Journals (Sweden)

    Farid Mohammadi

    2013-05-01

    Full Text Available The presence of the Catholic framework in J.R.R. Tolkien’s legendarium has long been the subject of debate. Various Tolkien scholars and literary critics have already written different critical interpretations to consider whether to assign The Lord of the Rings and The Silmarillion to Christian Mythology or not; numerous attempts have been made to clarify this statement. Therefore, the reasons, why it should be included in this category are many and various. There are several examples in Tolkien’s The Lord of the Rings that can be studied in relation to Christian themes and motives. Consequently, the aims of this paper are to study the possible similarities of Varda, Queen of the Stars, and Galadriel, the Lady of Light, to the Blessed Virgin Mary in Christian contexts. Moreover, to study the influence of Tolkien’s strong faith, which shaped his Catholic imagination, all through his legendarium, and subsequently leads us to observe Tolkien’s complete obedience to Catholicism, and especially, his profound devotion to the Blessed Virgin Mary.

  20. An old dog and new tricks: Genetic analysis of a Tudor dog recovered from the Mary Rose wreck.

    Science.gov (United States)

    Zouganelis, George D; Ogden, Rob; Nahar, Niru; Runfola, Valeria; Bonab, Maziar; Ardalan, Arman; Radford, David; Barnett, Ross; Larson, Greger; Hildred, Alex; Jones, Mark; Scarlett, Garry

    2014-12-01

    The Tudor warship the Mary Rose sank in the Solent waters between Portsmouth and the Isle of Wight on the 19th of July 1545, whilst engaging a French invasion fleet. The ship was rediscovered in 1971 and between 1979 and 1982 the entire contents of the ship were excavated resulting in the recovery of over 25,000 objects, including the skeleton of a small to medium sized dog referred to as the Mary Rose Dog (MRD). Here we report the extraction and analysis of both mitochondrial and genomic DNA from a tooth of this animal. Our results show that the MRD was a young male of a terrier type most closely related to modern Jack Russell Terriers with a light to dark brown coat colour. Interestingly, given the antiquity of the sample, the dog was heterozygotic for the SLC2A9 gene variant that leads to hyperuricosuria when found in modern homozygotic animals. These findings help shed light on a notable historical artefact from an important period in the development of modern dog breeds. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  1. Harraga dans la littérature francophone : Boualem Sansal, Tahar Ben Jelloun, Mathias Enard et Marie Ndiaye

    Directory of Open Access Journals (Sweden)

    Désirée Schyns

    2016-03-01

    Full Text Available Résumé : Le présent article offre une analyse de l’immigration clandestine représentée en fiction. Je commenterai quatre productions romanesques francophones qui évoquent la recherche d’une vie meilleure en Europe par des personnages des pays du Sud, à savoir l’Algérie (Boualem Sansal, le Maroc (Tahar Ben Jelloun et Mathias Enard, et un pays d’Afrique subsaharienne qui ne sera nulle part mentionné (Marie Ndiaye. Nous allons voir que Sansal se sert de la fiction pour dénoncer surtout la situation socio-politique en Algérie qui fait que tant de jeunes veulent quitter le pays. Tahar Ben Jelloun et Mathias Enard ont recours à des références intertextuelles afin de replacer le sujet de l’immigration clandestine dans un contexte plus large, et notamment de critiquer les relations coloniales et d’établir un lien avec le passé. Quant à Marie Ndiaye, elle interpelle le lecteur en donnant un témoignage déchirant de l’errance de son personnage, mais en même temps insère des éléments fantastiques qui créent une distance esthétique et affective par rapport à l’expérience migratoire.

  2. A Novel Technique for Transmission of M-Ary Signal through Wireless Fading Channel Using Wavelet Denoising

    Directory of Open Access Journals (Sweden)

    Md. Zahangir Alam

    2011-01-01

    Full Text Available The paper proposes a novel technique for reducing noise in M-ary signal transmission through wireless fading channel using wavelet denoising that play the key role. The paper also explains that the conventional threshold-based technique is not capable of denoising M-ary quadrature amplitude modulated (M-QAM signals having multilevel wavelet coefficients through wireless fading channels. A detailed step by step wavelet decomposition and reconstruction processes are discussed here to transform a signal function into wavelet coefficients using simulation software like MATLAB. A 16-QAM modulated symbol through a Rician fading channel is weighted by a control variable of complex form to force the mean of each detail coefficient except low frequency component to zero to enhance noiseless property. The bit error rate (BER performance of the simulation results are furnished to show the effectiveness of the proposed technique. The root mean square of the deviation of the reconstruct signal from the original signal is used to express the effectiveness of the proposed technique. The traditional denoising provides very high value (above 90% of the percentage root mean square difference (PDR and the proposed technique provides only 10% PDR value for the symbol through a noisy channel. The result of the simulation study reveals that the BER performance can be increased using an appropriate control variable to force the mean of each detail coefficient to zero.

  3. The Role of Rehabilitation in the Management of Patients with Charcot-Marie-Tooth Disease: Report of Two Cases.

    Science.gov (United States)

    Dimitrova, Erieta Nikolikj; Božinovikj, Ivana; Ristovska, Simona; Pejcikj, Aleksandra Hadzieva; Kolevska, Aleksandra; Hasani, Mirjeta

    2016-09-15

    Charcot-Marie-Tooth (CMT) disease is a hereditary disease with signs of chronic non-progressive motor-sensory neuropathy which is characterised by symmetric muscle atrophy and weakness of the distal portion of lower extremities. The aim is to present two cases with peroneal muscular atrophy, applied rehabilitation procedures and rehabilitation outcome. Patient DR, aged 51, and patient KH, aged 78. Both patients had weakness and pronounced atrophy of the distal portion of lower extremities, numbness down the legs, contractures in the ankles and walking difficulties. Evaluation of patients included a clinical examination, Barthel Index, Time Up and Go test, measurement of the ankle range of motion, and a manual muscle test. On admission, the Barthel Index score was 60 in the first case, and 80 in the second. The rehabilitation program included exercise therapy with for lower extremity, occupational therapy, stationary bicycle riding, galvanic current, water exercises, and ankle-foot orthoses for both legs. The therapy applied had no significant changes in the clinical neurological status of the patients, but yet it provided some improvement in ankle contractures, better mobility, and a more stable gait. The application of rehabilitation procedures in patients with Charcot-Marie-Tooth disease can improve their functional status and walking stability.

  4. A Rare Case of Charcot-Mari-Tooth Disease Type 2S in a 20-year-old Man

    Directory of Open Access Journals (Sweden)

    Natalia A. Shnayder

    2017-12-01

    Full Text Available Charcot-Marie-Tooth disease type 2 (CMT2S is rare form of Charcot-Marie-Tooth disease (CMT that is characterized by a mutation in the IGHMBP2 gene. This gene encodes a helicase superfamily member that binds a specific DNA sequence from the region of the immunoglobulin mu chain switch. Mutation of this gene leads to spinal muscle atrophy with respiratory distress type 1 and CMT2S. This case report presents a 20-year-old male with genetically confirmed CMT2S having clinical respiratory involvement and symmetrically involved lower extremities. DNA sequencing revealed a previously unknown heterozygous mutation in the exone 2 of the IGHMBP2 gene leading to the replacement of the amino acid in the 46 position of the protein (chr11q13.3: 68673587 G>C. These atypical features widen the clinical spectrum of CMT2S. In describing this clinical case, we also improve diagnostic management and try to increase the alertness of various doctors towards neuromuscular diseases, including CMT.

  5. Novel mutations in the PRX and the MTMR2 genes are responsible for unusual Charcot-Marie-Tooth disease phenotypes.

    Science.gov (United States)

    Nouioua, Sonia; Hamadouche, Tarik; Funalot, Benoit; Bernard, Rafaëlle; Bellatache, Nora; Bouderba, Radia; Grid, Djamel; Assami, Salima; Benhassine, Traki; Levy, Nicolas; Vallat, Jean-Michel; Tazir, Meriem

    2011-08-01

    Autosomal recessive Charcot-Marie-Tooth diseases, relatively common in Algeria due to high prevalence of consanguineous marriages, are clinically and genetically heterogeneous. We report on two consanguineous families with demyelinating autosomal recessive Charcot-Marie-Tooth disease (CMT4) associated with novel homozygous mutations in the MTMR2 gene, c.331dupA (p.Arg111LysfsX24) and PRX gene, c.1090C>T (p.Arg364X) respectively, and peculiar clinical phenotypes. The three patients with MTMR2 mutations (CMT4B1 family) had a typical phenotype of severe early onset motor and sensory neuropathy with typical focally folded myelin on nerve biopsy. Associated clinical features included vocal cord paresis, prominent chest deformities and claw hands. Contrasting with the classical presentation of CMT4F (early-onset Dejerine-Sottas phenotype), the four patients with PRX mutations (CMT4F family) had essentially a late age of onset and a protracted and relatively benign evolution, although they presented marked spine deformities. These observations broaden the spectrum of clinical phenotypes associated with these two CMT4 forms. Copyright © 2011 Elsevier B.V. All rights reserved.

  6. Jean-Marie Le Pen vs. Marine Le Pen : un ‘ethos émotif’ différent ?

    Directory of Open Access Journals (Sweden)

    Fabienne Baider

    2015-12-01

    Full Text Available This paper examines how the Front National’s electoral victories could be explained, partially, in terms of a new discursive rhetoric adopted by Marine Le Pen. In order to compare rhetorical strategies used by both Marine and Jean-Marie Le Pen and their impact on their followers, we use comparable data, which consist of press articles published during the presidential campaigns of each politician and postings by online discussants related to interviews. Using corpus linguistics tools and lexical semantics, we assess how differently both leaders position themselves emotionally and how this emotional positioning is reconstructed within the postings of the viewers. Although no important quantitative difference can be observed in the number of emotion key-words they used respectively, a shift in both politicians’ rhetoric positioning can be observed when analyzing the context in which these keywords are embedded. If Jean-Marie Le Pen focuses on negative feelings towards the Other (anger, resentment, Marine Le Pen promotes a positive ethos (empathy in order to detoxify the image of her party and broaden her electoral base.

  7. Hip dysplasia is more severe in Charcot-Marie-Tooth disease than in developmental dysplasia of the hip.

    Science.gov (United States)

    Novais, Eduardo N; Bixby, Sara D; Rennick, John; Carry, Patrick M; Kim, Young-Jo; Millis, Michael B

    2014-02-01

    Patients with Charcot-Marie-Tooth disease may develop hip dysplasia. Hip geometry in these patients has not been well described in the literature. We compared the hip morphometry in Charcot-Marie-Tooth hip dysplasia (CMTHD) and developmental dysplasia of the hip (DDH) in terms of extent of (1) acetabular dysplasia and subluxation, (2) acetabular anteversion and osseous support, (3) coxa valga and femoral version, and (4) osteoarthritis. Fourteen patients with CMTHD (19 hips; mean age, 23 years) presenting for periacetabular osteotomy were matched to 45 patients with DDH (45 hips; mean age, 21 years) based on age, sex, and BMI. We assessed acetabular dysplasia and subluxation using lateral center-edge angle (LCEA), anterior center-edge angle (ACEA), and acetabular roof angle of Tönnis (TA) on plain pelvic radiographs and acetabular volume, area of femoral head covered by acetabulum, and percentage of femoral head covered by acetabulum on three-dimensional CT reconstruction models. Acetabular version and bony support, femoral version, and neck-shaft angle were measured on two-dimensional axial CT scans. Hip osteoarthritis was graded radiographically according to Tönnis criteria. Acetabular dysplasia was more severe in CMTHD, as measured by smaller LCEA (p coxa valga (p coxa valga, and hip osteoarthritis was more severe in CMTHD. These findings are important in choosing the appropriate surgical strategy for patients affected by CMTHD.

  8. Chemical Achievers: The Human Face of the Chemical Sciences (by Mary Ellen Bowden)

    Science.gov (United States)

    Kauffman, George B.

    1999-02-01

    Chemical Heritage Foundation: Philadelphia, PA, 1997. viii + 180 pp. 21.6 x 27.8 cm. ISBN 0-941901-15-1. Paper. 20.00 (10.00 for high school teachers who provide documentation). At a 1991 summer workshop sponsored by the Chemical Heritage Foundation and taught by Derek A. Davenport and William B. Jensen, high school and college teachers of introductory chemistry requested a source of pictorial material about famous chemical scientists suitable as a classroom aid. CHF responded by publishing this attractive, inexpensive paperback volume, which reflects the considerable research effort needed to locate appropriate images and to write the biographical essays. Printed on heavy, glossy paper and spiral bound to facilitate conversion to overhead transparencies, it contains 157 images from pictorial collections at CHF and many other institutions on two types of achievers: the historical "greats" most often referred to in introductory courses, and scientists who made contributions in areas of the chemical sciences that are of special relevance to modern life and the career choices students will make. The pictures are intended to provide the "human face" of the book's subtitle- "to point to the human beings who had the insights and made the major advances that [teachers] ask students to master." Thus, for example, Boyle's law becomes less cold and abstract if the student can connect it with the two portraits of the Irish scientist even if his face is topped with a wig. Marie Curie can be seen in the role of wife and mother as well as genius scientist in the photographs of her with her two daughters, one of whom also became a Nobel laureate. And students are reminded of the ubiquity of the contribution of the chemical scientists to all aspects of our everyday life by the stories and pictures of Wallace Hume Carothers' path to nylon, Percy Lavon Julian's work on hormones, and Charles F. Chandler and Rachel Carson's efforts to preserve the environment. In addition to portraits

  9. El problema de la identidad nacional en la obra de José Carlos Mariátegui

    Directory of Open Access Journals (Sweden)

    Luis Veres

    2002-06-01

    Full Text Available Au début du XXe siècle, le mouvement « indigéniste » et les idées socialistes se propagent dans tout le Pérou. Nombre de jeunes écrivains, qui voulaient résoudre le problème indien au Pérou et en Amérique Latine, lisent avec beaucoup d’intérêt les ouvrages de Marx, Lénine et Engels. Le marxisme est perçu comme un programme pour expliquer le monde moderne. Cette idéologie influence l’œuvre de l’intellectuel le plus charismatique de cette époque : José Carlos Mariátegui. C’est dans ce contexte qu’il convient de situer son œuvre la plus importante, Siete ensayos de interpretación de la realidad peruana. Dans ce livre, Mariátegui rêve d’un Pérou « intégral », modèle national fondé sur l’unité de toutes les races. Mais, cet ouvrage est parsemé de contradictions qui brisent l’idée d’intégration : des problèmes sociaux et raciaux qui vont à l’encontre de cette cohésion nationale à laquelle Mariátegui aspire, et qui sont le reflet d’une méconnaissance de la réalité.At the beginning of the XXth century, the Indigenist movement and socialist ideology spread out all over Peru. The young writers read Marx, Lenin and Engels’books with a lot of interest, in order to cope with the Indian issue in Peru and South America. Marxism is considered as a valid model to explain the world. This ideology inspires one of the most charismatic intellectuals of this time : Carlos Mariátegui. Siete ensayos de interpretación de la realidad peruana, his most important work has to be replaced in this context. In this book, Mariátegui pleads for an « integral » Peru, a national model based on the unity of all races. But there are some contradictions in this book, which break the idea of integration: social and racial problems which are not consistent with the national cohesion that Mariátegui claims, and which point out some misunderstanding in his analysis of reality.En claro paralelismo con el

  10. Spécificité pastorale de la personnalité de Jean-Paul II selon Jean-Marie Lustiger

    Directory of Open Access Journals (Sweden)

    Ryszard Biernat

    2011-04-01

    Full Text Available Jean-Marie Lustiger admired John Paul II and he was devoted to him. They both had similar origin. The Cardinal of Paris often accompanied the pope in his pastoral visits. He perceived John Paul II as the man of Providence. He was convinced that God had prepared him to this role. Jean-Marie Lustiger emphasized the attitudes of John Paul II that attracted the attention and admiration of observers. For instance: pray, holiness, attentive pastor and good relation with young people. Jean-Marie Lustiger as an attentive observer also focused his attention on the pastoral methods of John Paul II. In his utterances he often perceived the following methods: each person was important, defense of person’s dignity, the ability to speak with each man, modern language, importance of the pastoral visits and sui generis spiritual pedagogic. Jean-Marie Lustiger noticed radical change of perspective in preaching and in pastoral action of John Paul II. According to him the pope perceived the challenges of the modern times, evaluated needs of the humanity and gave the appropriate answers. For these he did not choose politics, sociology or even anthropology as a re fl ection but addressed to the hurt human who was redeem by Jesus Christ.

  11. Transformaties van volksmuziek van de westelijke Balkan en de Servische Octoëchos (Byzantijnse kerkmuziek) in het oeuvre van Ljubica Marić

    NARCIS (Netherlands)

    Čičovački, B.

    2017-01-01

    Ljubica Marić (1909-2003) was een van de belangrijkste Servische componisten van de 20e eeuw en tegelijk ook een uitgesproken persoonlijkheid in de muziek van de 20e eeuw. Ze behoort tot de eerste generatie Servische componisten die het einddiploma compositie in Belgrado behaalde. In 1929 ging zij

  12. Supplementary Environmental Baseline Studies and Evaluation of the St. Mary’s River 1980. Great Lakes-St. Lawrence Seaway Navigation Season Extension Program

    Science.gov (United States)

    1981-07-01

    TIC FILE CO" piological Services Program FWSWOBS 80182.1 JULY 1981 SSUPPLEMENTARY ENVIRONMENTAL (N BASELINE STUDIES & EVALUATION I! OF THE ST. MARY’S...Iowa darter 4 4 Johnny darter 704 7 7 718 Logperch 48 9 1 58 Yellow perch 135 185 154 5 479 Wa] leye 46 9 9 64 Mottled sculpin 289 6 295 Slimy sculpin

  13. Küberkiusamine - kiusamise üks alaliike kahe Pärnu linna kooli näitel / Maris Jürgenson ; juhendaja Elma Künnapas

    Index Scriptorium Estoniae

    Jürgenson, Maris

    2013-01-01

    Pärnu Sütevaka Humanitaargümnaasiumi õpilase Maris Jürgensoni uurimustöö, mis põhineb Pärnu Sütevaka Humanitaargümnaasiumi ja Pärnu Vanalinna Põhikooli 6.-9. klassi õpilaste seas läbiviidud ankeetküsitlusel

  14. Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2

    NARCIS (Netherlands)

    Brewer, Megan Hwa; Ma, Ki Hwan; Beecham, Gary W.; Gopinath, Chetna; Baas, Frank; Choi, Byung-Ok; Reilly, Mary M.; Shy, Michael E.; Züchner, Stephan; Svaren, John; Antonellis, Anthony

    2014-01-01

    Loss-of-function mutations in the Src homology 3 (SH3) domain and tetratricopeptide repeats 2 (SH3TC2) gene cause autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy. The SH3TC2 protein has been implicated in promyelination signaling through axonal neuregulin-1 and the ERBB2 Schwann

  15. Biblical motives from the Book of Joshua and Book of Judges in the Hours about the Immaculate Conception of the Most Holy Virgin Mary

    Directory of Open Access Journals (Sweden)

    Krystian Ziaja

    2010-03-01

    Full Text Available The aim of the article is better understanding of the Hours concerning the Immaculate Conception of the Most Holy Virgin Mary. Following motives from the books of Joshua and Judges were taken into consideration: The light from Gabaon (Joshua 10, 10–13, Gedeon’s fleece (Judges 6, 36–40, Samson’s honeycomb (Judges 14, 1–11. After the discussion of the above mentioned three texts we may ascertain that the author of Hours about the Immaculate Conception of the Most Holy Virgin Mary with accurate aim refers the texts to the Most Holy Virgin Mary. Mary is the light from Gabaon, which showed people that he, whose mother she is, will make a salvation, the real victory that had been expected since Adam and Eve’s times. Moreover, she is the fleece of Gedeon because God made her a wonderful exception as among people only she was not stained by a sin. Furthermore, she is Samson’s honeycomb as inside her the one who is our Savior and our best food was born.

  16. La interpretación de José Carlos Mariátegui sobre la Revolución Mexicana

    National Research Council Canada - National Science Library

    Silvana G. Ferreyra

    2011-01-01

    En este artículo se analiza la interpretatión de José Carlos Mariátegui sobre el carácter de la Revolución Mexicana. En su desarrollo nos preguntamos sobre las causas que explican los cambios que fue sufriendo...

  17. Progression of motor axon dysfunction and ectopic Na(v)1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B

    DEFF Research Database (Denmark)

    Rosberg, Mette R.; Alvarez Herrero, Susana; Klein, Dennis

    2016-01-01

    Mice heterozygously deficient for the myelin protein P0 gene (P0+/-) develop a slowly progressing neuropathy modeling demyelinating Charcot-Marie-Tooth disease (CMT1B). The aim of the study was to investigate the long-term progression of motor dysfunction in P0+/- mice at 3, 7, 12 and 20months...

  18. Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie

    NARCIS (Netherlands)

    W.W. de Herder (Wouter)

    2009-01-01

    textabstractIn 1886 Pierre Marie used the term "acromegaly" for the first time and gave a full description of the characteristic clinical picture. However several others had already given clear clinical descriptions before him and sometimes had given the disease other names. After 1886, it gradually

  19. Idealism on ainus tarkus, mis maailma veel jäänud on / Linda-Mari Väli ; intervjueerinud Johanna Ross

    Index Scriptorium Estoniae

    Väli, Linda-Mari, 1988-

    2010-01-01

    Linda-Mari Väli alustas luuletustega, nüüdseks on ilmunud proosat ja romaan "Eikeegi, eikunagi, eiskusagil". Tema tekstides väljendub mure inimeste ja loomade tuleviku pärast, et kaasaegses kirjanduses on vähe idealismi

  20. Ethics at War: Review of Elizabeth Scannell-Desch and Mary Ellen Doherty, Nurses in War: Voices from Iraq and Afghanistan

    Directory of Open Access Journals (Sweden)

    Gillespie, Leigh-Anne

    2012-10-01

    Full Text Available In Nurses in War: Voices from Iraq and Afghanistan, Elizabeth Scannell-Desch and Mary Ellen Doherty take a journey through the lived experiences of 37 United States military nurses who served in Iraq or Afghanistan during the war years 2003 through 2010.

  1. Society Girl, Sob Sister, Journalism Educator: Mary Paxton Keeley, the First Woman Graduate of the School of Journalism at the University of Missouri.

    Science.gov (United States)

    Zang, Barbara

    Based on an examination of well-kept primary source material, this paper presents a personal and professional history of Mary Paxton Keeley, the first woman graduate of one of the first journalism schools in the United States, the School of Journalism at the University of Missouri. Starting with her early years, the paper explains that Keeley was…

  2. Mary Wollstonecraft polemic with the views of Jean J. Rousseau on the upbringing and education of women [Polemika Mary Wollstonecraft z poglądami Jeana J. Rousseau na temat wychowania i edukacji kobiet

    Directory of Open Access Journals (Sweden)

    Agnieszka SZCZAP

    2017-11-01

    Full Text Available This article presents the views of Mary Wollstonecraft on the education of women. Her views are the essence of Enlightenment thought. She believedin the power of human reason and the legitimacy of the slogan of the French Revolution. Proposed social reforms based on the ideas of freedom and equality, demanded the granting to women their civil and political rights. Sources of the programme are the theoretical assumptionsand personal experiences of the author. The philosophical foundations of liberalism were inspired by John Locke and the polemic of views on education advocated by Jean J. Rousseau. Rousseau believed that the main task of women is pleasing men, therefore, what should be developed in them are the qualities and habits that are used to achieve this. This postulates that girls and boys were educated in a different way. Wollstonecraft referring to the universality of reason insisted on an egalitarian model of education.

  3. The effects of Mary Rose conservation treatment on iron oxidation processes and microbial communities contributing to acid production in marine archaeological timbers.

    Science.gov (United States)

    Preston, Joanne; Smith, Andrew D; Schofield, Eleanor J; Chadwick, Alan V; Jones, Mark A; Watts, Joy E M

    2014-01-01

    The Tudor warship the Mary Rose has reached an important transition point in her conservation. The 19 year long process of spraying with polyethylene glycol (PEG) has been completed (April 29(th) 2013) and the hull is air drying under tightly controlled conditions. Acidophilic bacteria capable of oxidising iron and sulfur have been previously identified and enriched from unpreserved timbers of the Mary Rose, demonstrating that biological pathways of iron and sulfur oxidization existed potentially in this wood, before preservation with PEG. This study was designed to establish if the recycled PEG spray system was a reservoir of microorganisms capable of iron and sulfur oxidization during preservation of the Mary Rose. Microbial enrichments derived from PEG impregnated biofilm collected from underneath the Mary Rose hull, were examined to better understand the processes of cycling of iron. X-ray absorption spectroscopy was utilised to demonstrate the biological contribution to production of sulfuric acid in the wood. Using molecular microbiological techniques to examine these enrichment cultures, PEG was found to mediate a shift in the microbial community from a co-culture of Stenotrophomonas and Brevunidimonas sp, to a co-culture of Stenotrophomonas and the iron oxidising Alicyclobacillus sp. Evidence is presented that PEG is not an inert substance in relation to the redox cycling of iron. This is the first demonstration that solutions of PEG used in the conservation of the Mary Rose are promoting the oxidation of ferrous iron in acidic solutions, in which spontaneous abiotic oxidation does not occur in water. Critically, these results suggest PEG mediated redox cycling of iron between valence states in solutions of 75% PEG 200 and 50% PEG 2000 (v/v) at pH 3.0, with serious implications for the future use of PEG as a conservation material of iron rich wooden archaeological artefacts.

  4. The effects of Mary Rose conservation treatment on iron oxidation processes and microbial communities contributing to acid production in marine archaeological timbers.

    Directory of Open Access Journals (Sweden)

    Joanne Preston

    Full Text Available The Tudor warship the Mary Rose has reached an important transition point in her conservation. The 19 year long process of spraying with polyethylene glycol (PEG has been completed (April 29(th 2013 and the hull is air drying under tightly controlled conditions. Acidophilic bacteria capable of oxidising iron and sulfur have been previously identified and enriched from unpreserved timbers of the Mary Rose, demonstrating that biological pathways of iron and sulfur oxidization existed potentially in this wood, before preservation with PEG. This study was designed to establish if the recycled PEG spray system was a reservoir of microorganisms capable of iron and sulfur oxidization during preservation of the Mary Rose. Microbial enrichments derived from PEG impregnated biofilm collected from underneath the Mary Rose hull, were examined to better understand the processes of cycling of iron. X-ray absorption spectroscopy was utilised to demonstrate the biological contribution to production of sulfuric acid in the wood. Using molecular microbiological techniques to examine these enrichment cultures, PEG was found to mediate a shift in the microbial community from a co-culture of Stenotrophomonas and Brevunidimonas sp, to a co-culture of Stenotrophomonas and the iron oxidising Alicyclobacillus sp. Evidence is presented that PEG is not an inert substance in relation to the redox cycling of iron. This is the first demonstration that solutions of PEG used in the conservation of the Mary Rose are promoting the oxidation of ferrous iron in acidic solutions, in which spontaneous abiotic oxidation does not occur in water. Critically, these results suggest PEG mediated redox cycling of iron between valence states in solutions of 75% PEG 200 and 50% PEG 2000 (v/v at pH 3.0, with serious implications for the future use of PEG as a conservation material of iron rich wooden archaeological artefacts.

  5. Introduction to the EC's Marie Curie Initial Training Network (MC-ITN) project: Particle Training Network for European Radiotherapy (PARTNER)

    CERN Document Server

    Dosanjh, Manjit

    2013-01-01

    PARTNER (Particle Training Network for European Radiotherapy) is a project funded by the European Commission’s Marie Curie-ITN funding scheme through the ENLIGHT Platform for 5.6 million Euro. PARTNER has brought together academic institutes, research centres and leading European companies, focusing in particular on a specialized radiotherapy (RT) called hadron therapy (HT), interchangeably referred to as particle therapy (PT). The ultimate goal of HT is to deliver more effective treatment to cancer patients leading to major improvement in the health of citizens. In Europe, several hundred million Euro have been invested, since the beginning of this century, in PT. In this decade, the use of HT is rapidly growing across Europe, and there is an urgent need for qualified researchers from a range of disciplines to work on its translational research. In response to this need, the European community of HT, and in particular 10 leading academic institutes, research centres, companies and small and medium-sized en...

  6. Redefining the Poet as Healer: Valerie Gillies's Collaborative Role in the Edinburgh Marie Curie Hospice Quiet Room Project.

    Science.gov (United States)

    Severin, Laura

    2015-01-01

    This article examines the poetic contribution of Valerie Gillies, Edinburgh Makar (or poet of the city) from 2005-2008, to the Edinburgh Marie Curie Hospice Quiet Room, a new contemplation space for patients, families, and staff. In collaboration with others, Gillies created a transitional space for the Quiet Room, centered on the display of her sonnet, "A Place Apart." This space functions to comfort visitors to the Quiet Room by relocating them in their surroundings and offering the solace provided by nature and history. With this project, her first as Edinburgh Makar, Gillies redefines the role of the poet as healer and advocates for newer forms of palliative care that focus on patients' spiritual and emotional, as well as physical, wellbeing.

  7. Performance analysis of DS/CDMA with noncoherent M-ary orthogonal modulation in multipath fading channels

    Science.gov (United States)

    Jalloul, Louay M. A.; Holtzman, Jack M.

    1994-06-01

    In this paper, the performance of a DS/CDMA system using M-ary orthogonal modulation with noncoherent demodulation is evaluated. The system operates in a multipath fading channel. A RAKE receiver structure with equal gain combining is used for demodulation. An approximation to the bit error probability is given which depends only on the first- and second-order moments of the multipath energies. The analysis results are compared with the results from computer simulations. It is seen that the approximation is accurate for multipaths energies with realistic coefficient of variation. System performance is also evaluated in terms of the capacity, which is defined as the number of users that can be supported at a given bit error probability. The approximation is used to evaluate the capacity reductions due to power variations caused by multipath fading.

  8. Louis Nico Marie Duysens (March 15, 1921-September 8, 2015): a leading biophysicist of the 20th century.

    Science.gov (United States)

    Govindjee; Pulles, M P J

    2016-06-01

    Louis Nico Marie (L. N. M.) Duijsens (Duysens) was one of the giants in the biophysics of photosynthesis. His PhD thesis "Transfer of Excitation Energy in Photosynthesis" (Duysens, 1952) is a classic; he introduced light-induced absorption difference spectroscopy to photosynthesis research and proved the existence of reaction centers, introducing advanced methods from physics to understand biological processes. Further, it is his 1959-1961 seminal work, with Jan Amesz, that provided evidence for the existence of the series scheme for the two light reactions in oxygenic photosynthesis. In one word, he was one of the master biophysicists of the 20th century-who provided direct measurements on many key intermediates, and made us understand the intricacies of photosynthesis with a simplicity that no one else ever did. We present here our personal perspective of the scientist that Lou Duysens was. For an earlier perspective, see van Grondelle and van Gorkom (Photosynth Res 120: 3-7, 2014).

  9. La gravitación de ciertos conceptos sorelianos en el pensamiento de Mariátegui

    Directory of Open Access Journals (Sweden)

    Matías Zucconi

    2017-11-01

    Full Text Available El concepto de mito revolucionario es la idea de Georges Sorel más influyente en el pensamiento de José Carlos Mariátegui. Sin embargo, este concepto no funciona de la misma forma en ambos autores, fundamentalmente porque es aplicado en cada caso a coyunturas nacionales marcadamente diferentes, como las de Francia y Perú a principios del siglo XX. Por esta razón resulta importante, con independencia de las similitudes teóricas, diferenciar entre un mito expresado como huelga general, ligado al proletariado industrial europeo, y otro caracterizado en torno a la revolución social, ligado a las masas del campesinado indígena. En ambos casos vemos que este tipo de conceptos son funcionales a una ampliación de los límites del marxismo más allá del estalinismo y la III Internacional.

  10. Mary Carruthers & Jan M. Ziolkowski (dir.), The Medieval Craft of Memory. An Anthology of Texts and Pictures

    OpenAIRE

    Lejbowicz, Max

    2008-01-01

    Mary Carruthers et Jan M. Ziolkowski ont réuni neuf collaborateurs pour compléter avec cette anthologie deux des livres publiés précédemment par la première : The Book of Memory : A Study of Memory in Medieval Culture, Cambridge, 1990 et The Craft of Thought : Meditation, Rhetoric, and the Making of Images, 400-1200, Cambridge, 1998. Ces deux titres sont maintenant accessibles en français : Le Livre de la Mémoire. Une étude de la mémoire dans la culture médiévale, traduit de l’anglais par Dia...

  11. Coexistent Charcot-Marie-Tooth type 1A and type 2 diabetes mellitus neuropathies in a Chinese family

    Directory of Open Access Journals (Sweden)

    A-ping Sun

    2015-01-01

    Full Text Available Charcot-Marie-Tooth disease type 1A (CMT1A is caused by duplication of the peripheral myelin protein 22 (PMP22 gene on chromosome 17. It is the most common inherited demyelinating neuropathy. Type 2 diabetes mellitus is a common metabolic disorder that frequently causes predominantly sensory neuropathy. In this study, we report the occurrence of CMT1A in a Chinese family affected by type 2 diabetes mellitus. In this family, seven individuals had duplication of the PMP22 gene, although only four had clinical features of polyneuropathy. All CMT1A patients with a clinical phenotype also presented with type 2 diabetes mellitus. The other three individuals had no signs of CMT1A or type 2 diabetes mellitus. We believe that there may be a genetic link between these two diseases.

  12. Antoine-Marie Chambeyron (1797-1851): a forgotten disciple of Jean-Etienne Esquirol (1772-1840).

    Science.gov (United States)

    Walusinski, Olivier

    2017-09-01

    Antoine-Marie Chambeyron (1797-1851) was a disciple of Jean-Etienne Esquirol (1772-1840) that history forgot, undoubtedly because he made no original contribution to psychiatric nosography. In 1827, his interest in the medical-legal status of the insane led him to translate into French and annotate the first medical-legal psychiatric treatise ever published, which was the work of the German philosopher Johann Christoph Hoffbauer (1766-1827). His translation played a role in shaping the French Law of 1838, the first piece of modern legislation aimed at protecting the rights of mental patients and limiting the State's power to confine them arbitrarily. Chambeyron is among the least-cited contributors to the prestigious work of nineteenth-century French alienists.

  13. Pierre-Marie Loizeau, Martin Van Buren : The Little Magician, Hauppauge, NY, Nova History Publ., 2009

    Directory of Open Access Journals (Sweden)

    Jean-Marc Serme

    2010-09-01

    Full Text Available La biographie de Martin Van Buren par Pierre-Marie Loizeau trouve sa place parmi un nombre non négligeable d’ouvrages en anglais consacrés ces dernières années au huitième président des États-Unis. Ce grand politique d’avant la guerre de Sécession fut méprisé pendant longtemps par les historiens. Il faut dire qu’il paraissait bien frêle entre les deux imposants « noyers » d’Amérique : le Vieux, Andrew Jackson, et le Jeune, James K. Polk. Outre sa réputation de Renard Rusé, son goût immodéré p...

  14. Charcot-Marie-Tooth syndrome and neurofibromatosis type 1 with multiple neurofibromas of the entire spinal nerve roots.

    Science.gov (United States)

    Onu, David O; Hunn, Andrew W; Peters-Willke, Jens

    2013-07-13

    The coexistence of polyneuropathy which has the definite clinical and electromyographical findings consistent with Charcot-Marie-Tooth (CMT) syndrome and neurofibromatosis type 1 (NF1) has infrequently been reported. We describe a patient with both CMT and NF1, who had multiple neurofibromas involving the entire spinal neural axis. In addition, he had multiple neurofibromas distributed within the ileopsoas and gluteus muscles and subcutaneous tissues. These lesions were detected readily by MRI and the patient underwent successful surgical resection of the largest tumours compressing bilateral C2 nerve roots. To our knowledge, this is the first reported case of CMT syndrome coexisting with NF1 in which multiple neurofibromas involved the entire spinal nerve roots. We discuss the diagnostic and therapeutic challenges, emphasising the role of MRI and electrophysiology in such cases and provide a literature review.

  15. Le rêve communautaire de Marie-Claire Blais. Eschatologie et agapé dans le cycle de 'Soifs'

    Directory of Open Access Journals (Sweden)

    Petr Kyloušek

    2013-01-01

    Full Text Available Marie-Claire Blais seeks to innovate, throughout her career, her 'antimimétique' writing. Her extensive pentalogy - Soifs (1995, Dans la foudre et la lumière (2001, Augustino et le choeur de la destruction (2005, Naissance de Rebecca à l’ère des tourments (2008, Mai au bal des prédateurs (2010 – offers a complex existential questioning of the actual situation of the man. The problem of Evil and Good, which is in the heart of questions and answers, is treated with an original narration, transforming Virginia Woolf’s stream of consciousness. This innovation, however, is rooted in the tradition, namely its baroque poetics and its community orientation, both attached to the affirmation / negation of the catholic heritage that marked Quebec.

  16. Humor y subversión en la poética de Ricardo Mariño

    OpenAIRE

    Sardi, Valeria

    2015-01-01

    En este trabajo nos proponemos analizar la poética del escritor argentino Ricardo Mariño que se configura en una zona de cruces entre la puesta en juego del humor y la ruptura con los cánones genéricos. Es decir, su poética se caracteriza por la presencia del humor a partir de la utilización de diversas estrategias -como la inversión, la repetición, la exageración, entre otras- como así también la construcción de ficciones donde los géneros literarios son transgredidos para construir universo...

  17. Foot drop splints improve proximal as well as distal leg control during gait in Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Ramdharry, Gita M; Day, Brian L; Reilly, Mary M; Marsden, Jonathan F

    2012-10-01

    During walking, people with Charcot-Marie-Tooth (CMT) disease may compensate for distal weakness by using proximal muscles. We investigated the effect of different AFOs on distal leg control and proximal compensatory actions. Fourteen people with CMT were tested while wearing 3 types of ankle-foot orthosis (AFO) bilaterally compared with shoes alone. Walking was assessed using three-dimensional gait analysis. Stiffness of the splints was measured by applying controlled 5-degree ankle stretches using a motor. The results showed that each AFO significantly stiffened the ankle and increased ankle dorsiflexion at foot clearance compared with shoes alone. At push off, peak ankle power generation was reduced, but only with 1 type of AFO. A significant decrease in hip flexion amplitude during the swing phase was observed with all 3 AFOs. These results indicate that AFOs reduce foot drop and remove the need for some proximal compensatory action. Copyright © 2012 Wiley Periodicals, Inc.

  18. Messire Gilles de Chin natif de Tournesis, éd. Anne-Marie Liétard-Rouzé

    OpenAIRE

    Parussa, Gabriella

    2012-01-01

    Anne-Marie Liétard-Rouzé publie pour les Presses universitaires du Septentrion la biographie chevaleresque de Gilles de Chin en prose, d’après le manuscrit 50 du fonds Godefroy de la Bibliothèque municipale de Lille. Une autre version de cette même mise en prose a déjà été publiée en 1837 par R. Chalon et en 1954 par L. P. Cormier, d’après un deuxième manuscrit conservé à la Bibliothèque Royale de Belgique, sous la cote 10237. Le but de cette publication est donc de fournir une édition de la ...

  19. Phenotypic spectrum of Charcot-Marie-Tooth disease due to LITAF/SIMPLE mutations: a study of 18 patients.

    Science.gov (United States)

    Guimarães-Costa, R; Iancu Ferfoglia, R; Leonard-Louis, S; Ziegler, F; Magy, L; Fournier, E; Dubourg, O; Bouche, P; Maisonobe, T; Lacour, A; Moerman, A; Latour, P; Stojkovic, T

    2017-03-01

    Charcot-Marie-Tooth (CMT) 1C due to mutations in LITAF/SIMPLE is a rare subtype amongst the autosomal dominant demyelinating forms of CMT. Our objective was to report the clinical and electrophysiological characteristics of 18 CMT1C patients and compare them to 20 patients with PMP22 mutations: 10 CMT1A patients and 10 patients with hereditary neuropathy with liability to pressure palsies (HNPP). Charcot-Marie-Tooth 1C patients were followed-up in referral centres for neuromuscular diseases or were identified by familial survey. All CMT1A and HNPP patients were recruited at the referral centre for neuromuscular diseases of Pitié-Salpêtrière Hospital. Two phenotypes were identified amongst 18 CMT1C patients: the classical CMT form ('CMT-like', 11 cases) and a predominantly sensory form ('sensory form', seven cases). The mean CMT neuropathy score was 4.45 in CMT1C patients. Motor nerve conduction velocities in the upper limbs were significantly more reduced in CMT1A than in CMT1C patients. On the other hand, the motor nerve conduction velocity of the median nerve was significantly lower in CMT1C compared to the HNPP group. Distal motor latency was significantly more prolonged in CMT1A patients compared to the CMT1C and HNPP groups, the latter two groups having similar distal motor latency values. Molecular analysis revealed five new LITAF/SIMPLE mutations (Ala111Thr, Gly112Ala, Trp116Arg, Pro135Leu, Arg160Cys). Our study delineates CMT1C as mostly a mild form of neuropathy, and gives clinical and electrophysiological clues differentiating CMT1C from CMT1A and HNPP. Delineating phenotypes in CMT subtypes is important to orient molecular diagnosis and to help to interpret complex molecular findings. © 2017 EAN.

  20. A Novel N-Acetylglutamate Synthase Architecture Revealed by the Crystal Structure of the Bifunctional Enzyme from Maricaulis maris

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Dashuang; Li, Yongdong; Cabrera-Luque, Juan; Jin, Zhongmin; Yu, Xiaolin; Zhao, Gengxiang; Haskins, Nantaporn; Allewell, Norma M.; Tuchman, Mendel (Maryland); (GWU); (Georgia)

    2012-05-24

    Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, were identified in Maricaulis maris and several other bacteria. Arginine is an allosteric inhibitor of NAGS but not NAGK activity. The crystal structure of M. maris NAGS/K (mmNAGS/K) at 2.7 {angstrom} resolution indicates that it is a tetramer, in contrast to the hexameric structure of Neisseria gonorrhoeae NAGS. The quaternary structure of crystalline NAGS/K from Xanthomonas campestris (xcNAGS/K) is similar, and cross-linking experiments indicate that both mmNAGS/K and xcNAGS are tetramers in solution. Each subunit has an amino acid kinase (AAK) domain, which is likely responsible for N-acetylglutamate kinase (NAGK) activity and has a putative arginine binding site, and an N-acetyltransferase (NAT) domain that contains the putative NAGS active site. These structures and sequence comparisons suggest that the linker residue 291 may determine whether arginine acts as an allosteric inhibitor or activator in homologous enzymes in microorganisms and vertebrates. In addition, the angle of rotation between AAK and NAT domains varies among crystal forms and subunits within the tetramer. A rotation of 26{sup o} is sufficient to close the predicted AcCoA binding site, thus reducing enzymatic activity. Since mmNAGS/K has the highest degree of sequence homology to vertebrate NAGS of NAGS and NAGK enzymes whose structures have been determined, the mmNAGS/K structure was used to develop a structural model of human NAGS that is fully consistent with the functional effects of the 14 missense mutations that were identified in NAGS-deficient patients.

  1. The Causality of Casualness in the Translations of World Poetry: Jorie Graham vs Mary Oliver in Italy

    Directory of Open Access Journals (Sweden)

    Paola Loreto

    2014-10-01

    Full Text Available The essay explores the impact of poetry translation on the circulation of the works of American poets in Italy. The research is conducted by means of a double approach: in the first place, the aesthetic and cultural value of the poetry of two American women poets (Jorie Graham and Mary Oliver is assessed, whose work has received a radically different reception. Secondly, the reasons for this disparity of treatment are sought in the interrelation between the practices and activity of poetry translation and of publication, as they are customarily led in Italy. These are inferred from sample interviews with professionals in both fields. The results of the investigation highlight a combination of the casual and the causal, the causing factor being the occasional encounter of a poet with a translator, who then chooses his/her author, texts, and translating strategies according to his/her personal aesthetic, and sometimes ideological, judgment. Il saggio offre un’analisi dell’influenza delle traduzioni sulla circolazione della poesia americana contemporanea in Italia. La ricerca si articola in due momenti: in primo luogo viene fornita una valutazione estetica e culturale dell’opera di due poetesse americane, Jorie Graham e Mary Oliver, la cui ricezione in Italia è particolarmente significativa perché sta conoscendo fortune opposte; in secondo luogo viene condotta un’indagine dei motivi di questa disparità di trattamento nell’interazione tra le pratiche di traduzione e le dinamiche di pubblicazione in atto in Italia. Queste sono state dedotte da alcune interviste campione con professionisti dei due campi. I risultati hanno evidenziato una combinazione di fattori casuali e causali, nella quale l’incontro personale e a volte fortuito tra un poeta e un traduttore mette in moto strategie di selezione e di traduzione motivate da ragioni estetiche e a volte ideologiche. 

  2. Women's translations of scientific texts in the 18th century: a case study of Marie-Anne Lavoisier.

    Science.gov (United States)

    Kawashima, Keiko

    2011-01-01

    In the 18th century, many outstanding translations of scientific texts were done by women. These women were important mediators of science. However, I would like to raise the issue that the 'selection,' which is the process by which intellectual women chose to conduct translation works, and those 'selections' made by male translators, would not be made at the same level. For example, Émilie du Châtelet (1706-1749), the only French translator of Newton's "Principia," admitted her role as participating in important work, but, still, she was not perfectly satisfied with the position. For du Châtelet, the role as a translator was only an option under the current conditions that a female was denied the right to be a creator by society. In the case of Marie-Anne Lavoisier (1743-1794), like du Châtelet, we find an acute feeling in her mind that translation was not the work of creators. Because of her respect toward creative geniuses and her knowledge about the practical situation and concrete results of scientific studies, the translation works done by Marie-Anne Lavoisier were excellent. At the same time, the source of this excellence appears paradoxical at a glance: this excellence of translation was related closely with her low self-estimation in the field of science. Hence, we should not forget the gender problem that is behind such translations of scientific works done by women in that era. Such a possibility was a ray of light that was grasped by females, the sign of a gender that was eliminated from the center of scientific study due to social systems and norms and one of the few valuable opportunities to let people know of her own existence in the field of science.

  3. Mary SIDA y otras agresoras fatales en el folclore internáutico: enfermedad, miedo y mito

    Directory of Open Access Journals (Sweden)

    Ángel J. GONZALO TOBAJAS

    2015-04-01

    Full Text Available ABSTRACT: Although the urban legend's versions of «Mary AIDS» and its sequels are mainly transmitted through the new molds for the digital era (blogs, social networks, applications crossplatform messaging as WhatsApp and websites like YouTube, if it deepens in the territories of the oral and written literature, myth, History and the press notes that its content is much more traditional than we might imagine. Between parallels mentioned here, among others, an episode of the Gesta Romanorum, a Breton ballad of the Middle Ages, a popular tale of the Ozarks and a tale by Guy de Maupassant. Furthermore, it's linked here the protagonists of these stories with characters like the serranas of Spanish popular ballads and creatures as lamias, nymphs and succubi of different traditions, cultures and periods of time. RESUMEN: Aunque las versiones de las leyendas urbanas de «Mary SIDA» y sus secuelas se transmitan fundamentalmente a través de los nuevos moldes de la era digital (blogs, redes sociales, aplicaciones de mensajería multiplataforma como WhatsApp y sitios web como YouTube, si se profundiza en los territorios de la literatura oral y escrita, el mito, el cuento, la historia y la prensa se observa que su contenido es mucho más tradicional de lo que a priori se podría imaginar. Entre los paralelos mencionados en este artículo destaca, por ejemplo, un episodio de la Gesta Romanorum, una balada bretona de la Edad Media, un cuento popular de los Ozark y un conocido relato de Guy de Maupassant; asimismo, se vincula aquí a las protagonistas de estas leyendas con personajes como las serranas del Romancero popular y criaturas como las lamias, ninfas y súcubos de distintas tradiciones, culturas y épocas.

  4. Lõuna 2a villa restaureerimine Pärnus = Restoration of Lõuna 2a villa in Pärnu / Jaak Huimerind, Mari Kurismaa, Mart Kalm ; kommenteerinud Liina Jänes

    Index Scriptorium Estoniae

    Huimerind, Jaak, 1957-

    2015-01-01

    Villa Pärnus Lõuna tänav 2a, valminud 1936, restaureeritud 2014. Hoone arhitektid Olev Siinmaa, Anton Soans, restaureerimisarhitekt Jaak Huimerind, sisearhitekt Mari Kurismaa. Eesti Kultuurkapitali Arhitektuuri sihtkapitali restaureerimispreemia 2014

  5. 28 June 2012 - Members of the European Brain Council led by President Mary Baker visiting the LHC tunnel at Point 5 with Technology Department Group Leader L. Bottura and CMS experimental area with Run Coordinator M. Chamizo-Llatas.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    28 June 2012 - Members of the European Brain Council led by President Mary Baker visiting the LHC tunnel at Point 5 with Technology Department Group Leader L. Bottura and CMS experimental area with Run Coordinator M. Chamizo-Llatas.

  6. Mida arvate ideest, et kõrgkoole võiks juhtida ülikoolivälistest inimestest koosnev nõukogu? / Jaak Aaviksoo, Maris Mälzer, Peeter Kreitzberg, Peep Sürje

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele vastavad Tartu Ülikooli eelmine rektor Jaak Aaviksoo, Eesti Üliõpilaskondade Liidu esimees Maris Mälzer, Riigikogu kultuurikomisjoni esimees Peeter Kreitzberg ja Tallinna Tehnikaülikooli rektor Peep Sürje

  7. [Bakalaureuse-, magistri- ja doktorikraadiga töötute osast Eesti töötute seas. Miks ei leia kõrgharidusega, teaduskraadiga inimesed rakendust?] / Krista Loogma, Maris Mälzer, Hardo Aasmäe

    Index Scriptorium Estoniae

    Loogma, Krista, 1946-

    2010-01-01

    Küsimusele vastavad Tallinna Ülikooli kasvatusteaduste instituudi haridusuuringute keskuse juhataja Krista Loogma, Eesti üliõpilaskondade liidu juhatuse esimees Maris Mälzer ja majandusgeograaf Hardo Aasmäe

  8. Oceanographic profile data collected aboard Bella Marie and Thomas R. Dowell as part of project OPR-J977-TE-08 in the Gulf of Mexico on 2008-06-21 (NCEI Accession 0130646)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0130646 includes physical and profile data collected aboard the Bella Marie and Thomas R. Dowell during project OPR-J977-TE-08 in the Gulf of Mexico...

  9. Frankenstein, de Mary Shelley, e Drácula, de Bram Stoker: gênero e ciência na literatura Mary Shelley's Frankenstein and Bram Stoker's Dracula: gender and science in literature

    Directory of Open Access Journals (Sweden)

    Lucia de La Rocque

    2001-06-01

    Full Text Available As obras literárias têm, através dos tempos, dado voz aos medos e esperanças gerados pelas descobertas científicas e retratado as imagens e mitos em torno da própria idéia de ciência. Diversos parâmetros podem contribuir para estas representações da ciência, como a cultura e a classe social na qual estão inseridos os autores das obras em questão. Não se pode negar, também, a influência do gênero, já que, pela dominação da ciência pela esfera masculina de ação, o fato de a obra ser de autoria feminina ou masculina pode determinar uma peculiar caracterização do mundo científico. Neste artigo, através de uma análise comparativa de duas importantes obras literárias do século XIX, Frankenstein, de Mary Shelley, e Drácula, de Bram Stoker, são colocadas em relevo questões relativas à visão de ciência e sua relação com o gênero. Enquanto Shelley, como mulher, afastada do mundo científico, descortina em Frankenstein toda sua desconfiança em relação ao mesmo, Stoker, protótipo do homem vitoriano, imprime em Drácula sua sólida confiança na ciência.Throughout the ages, literary works have expressed fears and expectations generated by scientific discoveries and have portrayed images and myths about science itself. Several parameters can contribute to these representations of science, including the culture and social class to which the authors of these works belong. We also cannot deny the influence of gender, as due to the fact that the male sphere of action dominates science, male or female authoring can determine a peculiar characterization of the scientific world. In the present work, through a comparative analysis of two important literary works from the 19th century, Frankenstein, by Mary Shelley, and Dracula, by Bram Stoker, the issues concerning the view of science and their relation to gender are highlighted. While Shelley, as a woman, apart from the scientific world, reveals in Frankenstein all her

  10. Tota Pulchra – immaculate conception of the Blessed Virgin Mary as a work of the divine mercy on the basis of the writings of Blessed George Matulaitis-Matulewicz

    OpenAIRE

    Matulewicz, Elżbieta

    2008-01-01

    In the cycle of five theological articles published in 1903–1904 in polish diocesan magazine in Kielce (Poland) Blessed George Matulaitis-Matulewicz explained the substance of the Immaculate Conception of Blessed Virgin Mary dogma which was declared in 1854 by Pius IX. On the basis of these five articles the first dimension of the relation between the Immaculate Conception of Blessed Virgin Mary and the mystery of Divine Mercy is considered. Blessed George emphasizes that privilege of the Imm...

  11. El estatuto epistemológico de la transmisión de la acción: un estudio desde Mary Hesse ‘Forces and Fields’

    OpenAIRE

    Bujalance, L. (Laura); Cobreros, P. (Pablo)

    2018-01-01

    La presente tesis consta de tres partes que se corresponden con los tres aspectos de la obra de Hesse que se proponen para su revisión: su teoría de los modelos, el contexto filosófico que determinó sus propuestas y las conclusiones a las que llega a partir del estudio de los casos históricos. A estas tres partes les antecederá un análisis en profundidad de la obra de Mary Hesse. De este modo, este estudio se compondrá de 4 capítulos. En los dos primeros capítulos se analizará la obra de Mary...

  12. The gene encoding ganglioside-induced differentiation-associated protein 1 is mutated in axonal Charcot-Marie-Tooth type 4A disease.

    Science.gov (United States)

    Cuesta, Ana; Pedrola, Laia; Sevilla, Teresa; García-Planells, Javier; Chumillas, María José; Mayordomo, Fernando; LeGuern, Eric; Marín, Ignacio; Vílchez, Juan J; Palau, Francesc

    2002-01-01

    We identified three distinct mutations and six mutant alleles in GDAP1 in three families with axonal Charcot-Marie-Tooth (CMT) neuropathy and vocal cord paresis, which were previously linked to the CMT4A locus on chromosome 8q21.1. These results establish the molecular etiology of CMT4A (MIM 214400) and suggest that it may be associated with both axonal and demyelinating phenotypes.

  13. Introduction to the EC's Marie Curie Initial Training Network Project: The European Training Network in Digital Medical Imaging for Radiotherapy (ENTERVISION).

    Science.gov (United States)

    Dosanjh, Manjit; Cirilli, Manuela; Navin, Sparsh

    2015-01-01

    Between 2011 and 2015, the ENTERVISION Marie Curie Initial Training Network has been training 15 young researchers from a variety of backgrounds on topics ranging from in-beam Positron Emission Tomography or Single Particle Tomography techniques, to adaptive treatment planning, optical imaging, Monte Carlo simulations and biological phantom design. This article covers the main research activities, as well as the training scheme implemented by the participating institutes, which included academia, research, and industry.

  14. Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot?Marie?Tooth disease in a Norwegian family

    OpenAIRE

    Braathen, G. J.; H?yer, H.; Busk, ?. L.; Tveten, K.; Skjelbred, C. F.; Russell, M B

    2015-01-01

    Introduction Charcot?Marie?Tooth disease (CMT) is a heterogeneous inherited neuropathy. The number of known CMT genes is rapidly increasing mainly due to next?generation sequencing technology, at present more than 70 CMT?associated genes are known. We investigated whether variants in the DCTN2 could cause CMT. Material and methods Fifty?nine Norwegian CMT families from the general population with unknown genotype were tested by targeted next?generation sequencing (NGS) for variants in DCTN2 a...

  15. [Accepted Manuscript] Optimizing tubal ligation service delivery: a prospective cohort study to measure the task-sharing experience of Marie Stopes International Ethiopia.

    OpenAIRE

    Nuccio, O.; Sendek, B.; Park, M.H.; Mesele, T; Okello, F.O.; Gordon-Maclean, C.

    2016-01-01

    The Ethiopian government implements a progressive task-sharing policy for health services as a strategy to address shortages of highly skilled providers and increase access to critical services, such as family planning. Since 2009, Marie Stopes International Ethiopia has trained health officers to provide tubal ligations, a permanent method of family planning, as part of its task-sharing strategy. The objectives of this research were to evaluate task-sharing tubal ligations to health officers...

  16. [The chemical entries of Charles Gerhardt in Dictionnaire universel des Sciences, des Lettres et des Arts by Marie-Nicolas Bouillet].

    Science.gov (United States)

    Fournier, Josette

    2004-01-01

    Charles Gerhardt (1816-1856) is known as the founder of modern organic chemistry. He wrote the chemical entries of the dictionary managed by Marie-Nicolas Bouillet (1798-1864), who was a philosopher. This great deal of work was done between 1849 and 1853. It accounts for didactic and militant purposes of Gerhardt. The whole entries set up a true treatise of chemistry, and reflect the synthetic mind of their author.

  17. Kaadrid otsustavad endiselt kõik / Kersti Kivirüüt, Epp Adler, Andi Einaste, Maris Liiders ; intervjueerinud Meeli Parijõgi

    Index Scriptorium Estoniae

    2014-01-01

    Saku gümnaasiumis arutleti õpilaste korraldatud foorumil Eesti hariduse oleviku ja tuleviku üle. Intervjuu külalisesinejatega, kelleks tänavu olid haridus- ja teadusministeeriumi üldharidusosakonna peaekspert Kersti Kivirüüt, Epp Adler MTÜ-st HeadEst, Saku abivallavanem haridus-, kultuuri- ja sotsiaalhoolekande alal Andi Einaste ning Harju maavalitsuse haridus- ja sotsiaalosakonna juhataja Maris Liiders

  18. Mis on õpetajatöö kõige problemaatilisemad tahud? / Karoliine Piksarv, Ülle Uulma, Mari-Vivian Laht ... [jt.

    Index Scriptorium Estoniae

    2012-01-01

    Küsimusele vastasid Ülenurme gümnaasiumi inglise keele õpetaja Karoliine Piksarv, Jakob Westholmi gümnaasiumi eesti keele ja kirjanduse õpetaja Ülle Uulma, Kiltsi põhikooli eesti keele ja kirjanduse õpetaja Mari-Vivian Laht, Tallinna ühisgümnaasiumi meedia- ja kommunikatsiooniõpetaja Peeter-Eerik Ots, Tallinna Nõmme gümnaasiumi ajaloo, ühiskonnaõpetuse ja filosoofia õpetaja Indrek Riigor

  19. IsoNose - Isotopic Tools as Novel Sensors of Earth Surfaces Resources - A new Marie Curie Initial Training Network

    Science.gov (United States)

    von Blanckenburg, Friedhelm; Bouchez, Julien; Bouman, Caludia; Kamber, Balz; Gaillardet, Jérôme; Gorbushina, Anna; James, Rachael; Oelkers, Eric; Tesmer, Maja; Ashton, John

    2015-04-01

    The Marie Curie Initial Training Network »Isotopic Tools as Novel Sensors of Earth Surfaces Resources - IsoNose« is an alliance of eight international partners and five associated partners from science and industry. The project is coordinated at the Helmholtz Centre Potsdam GFZ German Research Centre for Geosciences and will run until February 2018. In the last 15 years advances in novel mass-spectrometric methods have opened opportunities to identify "isotopic fingerprints" of virtually all metals and to make use of the complete information contained in these fingerprints. The understanding developed with these new tools will ultimately guide the exploitation of Earth surface environments. However, progress in bringing these methods to end-users depends on a multi transfer of knowledge between (1) isotope Geochemistry and Microbiology, Environmental Sciences (2), Economic Geology and (3) instrument developers and users in the development of user-friendly and new mass spectrometric methods. IsoNose will focus on three major Earth surface resources: soil, water and metals. These resources are currently being exploited to an unprecedented extent and their efficient management is essential for future sustainable development. Novel stable isotope techniques will disclose the processes generating (e.g. weathering, mineral ore formation) and destroying (e.g. erosion, pollution) these resources. Within this field the following questions will be addressed and answered: - How do novel stable isotope signatures characterize weathering processes? - How do novel stable isotope signatures trace water transport? - How to use novel stable isotope as environmental tracers? - How to use novel stable isotope for detecting and exploring metal ores? - How to improve analytical capabilities and develop robust routine applications for novel stable isotopes? Starting from the central questions mentioned above the IsoNose activities are organized in five scientific work packages: 1

  20. Assessment of Targeted Next-Generation Sequencing as a Tool for the Diagnosis of Charcot-Marie-Tooth Disease and Hereditary Motor Neuropathy.

    Science.gov (United States)

    Lupo, Vincenzo; García-García, Francisco; Sancho, Paula; Tello, Cristina; García-Romero, Mar; Villarreal, Liliana; Alberti, Antonia; Sivera, Rafael; Dopazo, Joaquín; Pascual-Pascual, Samuel I; Márquez-Infante, Celedonio; Casasnovas, Carlos; Sevilla, Teresa; Espinós, Carmen

    2016-03-01

    Charcot-Marie-Tooth disease is characterized by broad genetic heterogeneity with >50 known disease-associated genes. Mutations in some of these genes can cause a pure motor form of hereditary motor neuropathy, the genetics of which are poorly characterized. We designed a panel comprising 56 genes associated with Charcot-Marie-Tooth disease/hereditary motor neuropathy. We validated this diagnostic tool by first testing 11 patients with pathological mutations. A cohort of 33 affected subjects was selected for this study. The DNAJB2 c.352+1G>A mutation was detected in two cases; novel changes and/or variants with low frequency (A mutation was also detected in three additional families. On haplotype analysis, all of the patients from these five families shared the same haplotype; therefore, the DNAJB2 c.352+1G>A mutation may be a founder event. Our gene panel allowed us to perform a very rapid and cost-effective screening of genes involved in Charcot-Marie-Tooth disease/hereditary motor neuropathy. Our diagnostic strategy was robust in terms of both coverage and read depth for all of the genes and patient samples. These findings demonstrate the difficulty in achieving a definitive molecular diagnosis because of the complexity of interpreting new variants and the genetic heterogeneity that is associated with these neuropathies. Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.