Personāla vadīšana Valsts ieņēmumu dienesta Rīgas muitas reģionālajā iestādē

OpenAIRE

Beinerte, Inga

2009-01-01

Lai veiksmīgi uzsāktu uzņēmuma vadīšanu ir nepieciešami noteikti resursi, uz ko balstīt uzņēmumu. Visneprognozējamākie un grūtāk vadāmie no šiem resursiem ir cilvēkresursi. Bez cilvēkresursiem nav iedomājama uzņēmējdarbība, jo tie izgudro un ražo preces, sniedz pakalpojumus, vada un kontrolē procesu darbību, kā arī kontrolē to kvalitāti. Maģistra darba „Personāla vadīšana Valsts ieņēmumu dienesta Rīgas muitas reģionālajā iestādē” mērķis ir izpētīt personāla vadību, tās būtību un izanalizē...

Synergy of first principles modelling with predictive control for a biventricular assist device: In silico evaluation study.

Science.gov (United States)

Koh, Vivian C A; Yong Kuen Ho; Stevens, Michael C; Salamonsen, Robert F; Lovell, Nigel H; Lim, Einly

2017-07-01

Control for dual rotary left ventricular assist devices (LVADs) used as a biventricular assist device (BiVAD) is challenging. If the control system fails, flow imbalance between the systemic and the pulmonary circulations would result, subsequently leading to ventricular suction or pulmonary congestion. With the expectation that advanced control approaches such as model predictive control could address the challenges naturally and effectively, we developed a synergistic first principles model predictive controller (MPC) for the BiVAD. The internal model of the MPC is a simplified state-space model that has been developed and validated in a previous study. A single Frank-Starling (FS) control curve was used to define the target pump flow corresponding to the preload on each side of the heart. The MPC was evaluated in a validated numerical model using three clinical scenarios: blood loss, myocardial recovery, and exercise. Simulation results showed that the MPC was effective in adapting to changes in physiological states without causing ventricular suction or pulmonary congestion. The use of MPC for a BiVAD eliminates the need for two controllers of dual LVADs thus making the task of controller tuning easier.

"Isa kuhu need värvid jäävad ..." : [luuletused] / Jaan Kaplinski

Index Scriptorium Estoniae

Kaplinski, Jaan, 1941-

2002-01-01

Sisu: "Isa kuhu need värvid jäävad ..." ; Lume ootamine ; "Oh sina paha peavalu ..." ; "Märg on vihmal märg on kastel ..." ; "Peet kisub peeti ..." ; "Küllap väikestel mustadel ..." ; "Mart haigutab ..." ; Kuu ; Teremees Tõnu ; Jalgrataste talveuni ; Kitsu ja kätsu ; Siret siret siterkuuti ; Suve soe silmadesse ; Iirimaal on ilmalapsed ; Miks ; Sügisel ; Täis ; Mis algab ; Aeg ; "Ma koiduajal ärkasin ..."

Klientu attiecību sociālās vadības ietekme uz klientu lojalitāti; sociālā tīkla Facebook piemērs

OpenAIRE

Avotiņa, Lelde

2015-01-01

Maģistra darba “Klientu attiecību sociālās vadības ietekme uz klientu lojalitāti; sociālā tīkla Facebook piemērs” mērķis ir noteikt un analizēt faktorus, kas ietekmē lojālo klientu piesaistīšanu un noturēšanu sociālo mediju vidē klientu attiecību sociālās vadības kontekstā. Maģistra darba pirmajā nodaļā tiek aplūkoti jautājumi, kas skar klientu lojalitāti, klientu attiecību vadību, klientu lomu sociālo mediju kontekstā un klientu attiecību sociālo vadību. Šī teorētiskā apkopojuma rezultātā...

Latvijas sabiedrisko attiecību aģentūru prakse plānotas krīzes komunikācijas vadīšanā

OpenAIRE

Štokmane, Linda

2014-01-01

Darba nosaukums ir „Latvijas sabiedrisko attiecību aģentūru prakse plānotas krīzes komunikācijas vadīšanā”. Pētījuma problēma - vai krīzes situācijām iespējams sagatavoties un kā iepriekš plānota un sagatavota komunikācija spēj palīdzēt efektīvāk vadīt krīzes situācijas? Bakalaura darba mērķis ir izpētīt, kāda ir Latvijas sab iedrisko attiecību aģentūru prakse un pieredze krīzes komunikācijas plānošanā un vadīšanā. Darba teorētiskā bāze, galvenokārt, balstīta uz situatīvo krīzes komunikāci...

Determining the Velocity Fine Structure by a Laser Anemometer in VAD operation

DEFF Research Database (Denmark)

Kristensen, Leif; Kirkegaard, Peter; Mikkelsen, Torben

. Then it is necessary to “create” a mean wind by turning the laser beam. Since the instrument is not moved the beam will describe a cone which could be a VAD-scanning. In any case the measured velocity components will not be parallel and this implies that the measured structure function will contain a term which...... is proportional to the total variance. The theoretical expression for the line-filtered structure function is derived in two equivalent ways, one in physical space and one in wave-number space, of which the last can be reliably evaluated by numerical integration. Also a practical approximate equation, derived...

Totally implantable total artificial heart and ventricular assist device with multipurpose miniature electromechanical energy system.

Science.gov (United States)

Takatani, S; Orime, Y; Tasai, K; Ohara, Y; Naito, K; Mizuguchi, K; Makinouchi, K; Damm, G; Glueck, J; Ling, J

1994-01-01

A multipurpose miniature electromechanical energy system has been developed to yield a compact, efficient, durable, and biocompatible total artificial heart (TAH) and ventricular assist device (VAD). Associated controller-driver electronics were recently miniaturized and converted into hybrid circuits. The hybrid controller consists of a microprocessor and controller, motor driver, Hall sensor, and commutation circuit hybrids. The sizing study demonstrated that all these components can be incorporated in the pumping unit of the TAH and VAD, particularly in the centerpiece of the TAH and the motor housing of the VAD. Both TAH and VAD pumping units will start when their power line is connected to either the internal power pack or the external battery unit. As a redundant driving and diagnostic port, an emergency port was newly added and will be placed in subcutaneous location. In case of system failure, the skin will be cut down, and an external motor drive or a pneumatic driver will be connected to this port to run the TAH. This will minimize the circulatory arrest time. Overall efficiency of the TAH without the transcutaneous energy transmission system was 14-18% to deliver pump outputs of 4-9 L/min against the right and left afterload pressures of 25 and 100 mm Hg. The internal power requirement ranged from 6 to 13 W. The rechargeable batteries such as NiCd or NiMH with 1 AH capacity can run the TAH for 30-45 min. The external power requirement, when TETS efficiency of 75% was assumed, ranged from 8 to 18 W. The accelerated endurance test in the 42 degrees C saline bath demonstrated stable performance over 4 months. Long-term endurance and chronic animal studies will continue toward a system with 5 years durability by the year 2000.

Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model

Directory of Open Access Journals (Sweden)

Ozlem Equils

2009-01-01

Full Text Available Caspases and apoptosis are thought to play a role in infection-associated preterm-delivery. We have shown that in vitro treatment with pancaspase inhibitor Z-VAD-FMK protects trophoblasts from microbial antigen-induced apoptosis. Objective. To examine whether in vivo administration of Z-VAD-FMK would prevent infection-induced preterm-delivery. Methods. We injected 14.5 day-pregnant-mice with heat-killed group B streptococcus (HK-GBS. Apoptosis within placentas and membranes was assessed by TUNEL staining. Calpain expression and caspase-3 activation were assessed by immunohistochemistry. Preterm-delivery was defined as expulsion of a fetus within 48 hours after injection. Results. Intrauterine (i.u. or intraperitoneal (i.p. HK-GBS injection led to preterm-delivery and induced apoptosis in placentas and membranes at 14 hours. The expression of calpain, a caspase-independent inducer of apoptosis, was increased in placenta. Treatment with the specific caspase inhibitor Z-VAD-FMK (i.p. prior to HK-GBS (i.p. delayed but did not prevent preterm-delivery. Conclusion. Caspase-dependent apoptosis appears to play a role in the timing but not the occurrence of GBS-induced preterm delivery in the mouse.

Systemic and Disease-Specific Risk Factors in Vascular Dementia: Diagnosis and Prevention

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Efraim Jaul

2017-10-01

Full Text Available In order to prevent the onset of vascular dementia (VaD in aging individuals, it is critical to detect clinically relevant vascular and systemic pathophysiological changes to signal the onset of its preceding prodromal stages. Identifying behavioral and neurobiological markers that are highly sensitive to VaD classification vs. other dementias is likely to assist in developing novel preventive treatment strategies that could delay the onset of disruptive psychomotor symptoms, decrease hospitalizations, and increase the quality of life in clinically-high-risk aging individuals. In light of empirical diagnostic and clinical findings associated with VaD pathophysiology, the current investigation will suggest a few clinically-validated biomarker measures of prodromal VaD cognitive impairments that are correlated with vascular symptomology, and VaD endophenotypes in non-demented aging people. In prodromal VaD individuals, distinguishing VaD from other dementias (e.g., Alzheimer's disease could facilitate specific early preventive interventions that significantly delay more severe cognitive deterioration or indirectly suppress the onset of dementia with vascular etiology. Importantly, the authors conclude that primary prevention strategies should examine aging individuals by employing comprehensive geriatric assessment approach, taking into account their medical history, and longitudinally noting their vascular, systemic, cognitive, behavioral, and clinical functional status. Secondary prevention strategies may include monitoring chronic medication as well as promoting programs that facilitate social interaction and every-day activities.

Development of a Voice Activity Controlled Noise Canceller

Science.gov (United States)

Abid Noor, Ali O.; Samad, Salina Abdul; Hussain, Aini

2012-01-01

In this paper, a variable threshold voice activity detector (VAD) is developed to control the operation of a two-sensor adaptive noise canceller (ANC). The VAD prohibits the reference input of the ANC from containing some strength of actual speech signal during adaptation periods. The novelty of this approach resides in using the residual output from the noise canceller to control the decisions made by the VAD. Thresholds of full-band energy and zero-crossing features are adjusted according to the residual output of the adaptive filter. Performance evaluation of the proposed approach is quoted in terms of signal to noise ratio improvements as well mean square error (MSE) convergence of the ANC. The new approach showed an improved noise cancellation performance when tested under several types of environmental noise. Furthermore, the computational power of the adaptive process is reduced since the output of the adaptive filter is efficiently calculated only during non-speech periods. PMID:22778667

Development of a Voice Activity Controlled Noise Canceller

Directory of Open Access Journals (Sweden)

Aini Hussain

2012-05-01

Full Text Available In this paper, a variable threshold voice activity detector (VAD is developed to control the operation of a two-sensor adaptive noise canceller (ANC. The VAD prohibits the reference input of the ANC from containing some strength of actual speech signal during adaptation periods. The novelty of this approach resides in using the residual output from the noise canceller to control the decisions made by the VAD. Thresholds of full-band energy and zero-crossing features are adjusted according to the residual output of the adaptive filter. Performance evaluation of the proposed approach is quoted in terms of signal to noise ratio improvements as well mean square error (MSE convergence of the ANC. The new approach showed an improved noise cancellation performance when tested under several types of environmental noise. Furthermore, the computational power of the adaptive process is reduced since the output of the adaptive filter is efficiently calculated only during non-speech periods.

Suppression of human T cell proliferation by the caspase inhibitors, z-VAD-FMK and z-IETD-FMK is independent of their caspase inhibition properties

Energy Technology Data Exchange (ETDEWEB)

Lawrence, C.P. [Medical Research Council Toxicology Unit, Hodgkin Building, Lancaster Road, University of Leicester, Leicester LE1 9HN (United Kingdom); Chow, S.C., E-mail: chow.sek.chuen@monash.edu [School of Science, Monash University Sunway Campus, Jalan Lagoon Selatan, Bandar Sunway, 46150 Selangor Darul Ehsan (Malaysia)

2012-11-15

The caspase inhibitors, benzyloxycarbony (Cbz)-l-Val-Ala-Asp (OMe)-fluoromethylketone (z-VAD-FMK) and benzyloxycarbonyl (Cbz)-Ile-Glu (OMe)-Thr-Asp (OMe)-FMK (z-IETD-FMK) at non-toxic doses were found to be immunosuppressive and inhibit human T cell proliferation induced by mitogens and IL-2 in vitro. Both caspase inhibitors were shown to block NF-κB in activated primary T cells, but have little inhibitory effect on the secretion of IL-2 and IFN-γ during T cell activation. However, the expression of IL-2 receptor α-chain (CD25) in activated T cells was inhibited by both z-VAD-FMK and z-IETD-FMK, whereas the expression of the early activated T cell marker, CD69 was unaffected. During primary T cell activation via the antigen receptor, both caspase-8 and caspase-3 were activated and processed to their respective subunits, but neither caspase inhibitors had any effect on the processing of these two caspases. In sharp contrast both caspase inhibitors readily blocked apoptosis and the activation of caspases during FasL-induced apoptosis in activated primary T cells and Jurkat T cells. Collectively, the results demonstrate that both z-VAD-FMK and z-IETD-FMK are immunosuppressive in vitro and inhibit T cell proliferation without blocking the processing of caspase-8 and caspase-3. -- Highlights: ► Caspase-8 and caspase-3 were activated during T cell activation and proliferation. ► T cell proliferation was blocked by caspase inhibitors. ► Caspase activation during T cell proliferation was not block by caspase inhibitors.

Left ventricular assist device (lvad design features: literature review

Directory of Open Access Journals (Sweden)

Yu. V. Bogdanova

2014-01-01

Full Text Available More than 8 million people in our country suffer from heart failure. About one million of these people die each year [1]. The problem of ventricular assist device creating - a mechanical device used for partial or complete replacement of heart function - is investigated for a long time (according to [2] just in our country since the 1970s. Today plenty of encouraging results are received. There is a number of VAD models which are successfully applied to patients with heart failure. After implantation, patients conduct a way of life that is normal in many respects: they are in the family, often they have an opportunity to work in their former specialty. Some of them live with the device about 8 years [3].According to [4] for 2010 the estimated total number of long-term devices implanted in the United States per year is over 1,700 (the population of the U.S. is 305 million, compared with over 430 per year in Europe (the population of Europe is 731 million. Unfortunately, people who need a heart transplant are much more.The principle of VAD is that being connected to the left ventricle with one cannula and to the ascending aorta with the other cannula the pump fully or partially replaces the function of the natural heart. This scheme allows the use of VAD in two ways: as a "bridge to transplantation" when the device is used temporarily until the donor heart is found, and a "bridge to recovery", when through the use of VAD the function of the heart muscle is recovered.VAD system can be divided into three subsystems: blood pump, power supply system and control system (Fig. 1.Each subsystem can be the subject of separate study. Special role in the development of VAD plays medical side of the issue. Successful research and development require interaction with qualified professionals in this field. The development of VAD is a multidisciplinary problem which demands fulfilment of a number of requirements.One of the most active programs in implantation of

Innovative Free-range Resonant Electrical Energy Delivery system (FREE-D System) for a ventricular assist device using wireless power.

Science.gov (United States)

Waters, Benjamin H; Smith, Joshua R; Bonde, Pramod

2014-01-01

Technological innovation of a smaller, single moving part has an advantage over earlier large pulsatile ventricular assist devices (VADs) prone to mechanical failure. Drivelines limit the potential for extended patient survival durations with newer pumps and act as source for infection, increased morbidity, rehospitalizations, and reduced quality of life. The Free-range Resonant Electrical Energy Delivery (FREE-D) wireless power system uses magnetically coupled resonators to efficiently transfer power. We demonstrate the efficiency over distance of this system. The experimental setup consists of an radiofrequency amplifier and control board which drives the transmit resonator coil, and a receiver unit consisting of a resonant coil attached to a radiofrequency rectifier and power management module. The power management module supplies power to the axial pump, which was set at 9,600 rpm. To achieve a seamless wireless delivery in any room size, we introduced a third relay coil. This relay coil can be installed throughout a room, whereas a single relay coil could be built into a jacket worn by the patient, which would always be within range of the receive coil implanted in the patient's body. The power was delivered over a meter distance without interruptions or fluctuations with coil, rectifier, and regulator efficiency more than 80% and overall system efficiency of 61%. The axial pump worked well throughout the 8 hours of continuous operation. Having same setup on the opposite side can double the distance. A tether-free operation of a VAD can be achieved by FREE-D system in room-size distances. It has the potential to make the VAD therapy more acceptable from the patient perspective.

Informatīva uzņēmuma vadības sistēma

OpenAIRE

Salzemnieks, Aldis

2009-01-01

Informatīva uzņēmuma vadības sistēma piedāvā ērti un ātri pārlūkot informāciju par darbiniekiem, klientiem un finansiālajām attiecībām pret klientiem, kontrolēt uzņēmuma darbinieku veiktās darbības un veiksmīgi sadalīt darbus starp darbiniekiem. Sistēmu iespējams uzstādīt tā, lai piekļuve tai caur pārlūkprogrammu būtu gan no iekšējā datortīklā, gan arī tīmeklī. Tas nodrošina ātru, kvalitatīvu un organizētu darba izpildi, kā arī ietaupa laiku. Sistēmā iespējams izveidot lietotājus ar dažādiem ...

Wireless patient monitoring system for a moving-actuator type artificial heart.

Science.gov (United States)

Nam, K W; Chung, J; Choi, S W; Sun, K; Min, B G

2006-10-01

In this study, we developed a wireless monitoring system for outpatients equipped with a moving-actuator type pulsatile bi-ventricular assist device, AnyHeart. The developed monitoring system consists of two parts; a Bluetooth-based short-distance self-monitoring system that can monitor and control the operating status of a VAD using a Bluetooth-embedded personal digital assistant or a personal computer within a distance of 10 meters, and a cellular network-based remote monitoring system that can continuously monitor and control the operating status of AnyHeart at any location. Results of in vitro experiments demonstrate the developed system's ability to monitor the operational status of an implanted AnyHeart.

[Treatment of vascular dementia by Chinese herbal medicine: a systematic review of randomized controlled trials of clinical studies].

Science.gov (United States)

Jian, Wen-Jia; Shi, Jing; Tian, Jin-Zhou; Ni, Jing-Nian

2015-01-01

Chinese herbal medicine has been extensively used in the treatment of vascular dementia (VaD), but lacked systematic review on its efficacy and safety. So we conducted a systematic review to assess the efficacy and safety of Chinese herbal medicine in treating VaD. CNKI, CBM, PubMed, and Wiley Online Library were retrieved for randomized trials (RCTs) on Chinese herbal medicine treating VaD patients. Randomized parallel control trials by taking Chinese herbal medicine as one treatment method and placebos/cholinesterase inhibitors/Memantine hydrochloride as the control were included. Quality rating and data extraction were performed. RevMan5.2.0 Software was used for meta-analysis. Standardized mean difference (SMD) at 95% confidence interval (CI) was used to indicate effect indicators of results. Seven RCTs met the inclusive criteria. Totally 677 VaD patients were randomly assigned to the treatment group and the control group. Descriptive analyses were performed in inclusive trials. The cognitive function was assessed in all trials. Results showed Mini-Mental state examination (MMSE) score was better in the Chinese herbal medicine group than in the placebo group, but with no significant difference when compared with the donepezil group (P > 0.05). Adverse reactions were mainly manifested as gastrointestinal symptoms such as abdominal pain in the Chinese herbal medicine group. But they occurred more in the donepezil group than in the Chinese herbal medicine group. The methodological quality of included trials was poor with less samples. Results of different trials were lack of consistency. Present evidence is not sufficient to prove or disapprove the role of Chinese herbal medicine in improving clinical symptoms and outcome indicators of VaD patients. Their clinical efficacy and safety need to be supported by more higher quality RCTs.

Vad och hur gör de? − att synliggöra lärande i grundskolans slöjdpraktik via videoetnografi och mikroanalys

Directory of Open Access Journals (Sweden)

Marléne Johansson

2011-11-01

Full Text Available Artikeln bygger på resultat och erfarenheter av etnografiskt insamlade videoinspelningar från grundskolans slöjdundervisning utgående från tre studier; dels vid ett projekt med förstudier under slutet av 1990-talet (Johansson, 1996, dels vid avhandlingsprojektet Slöjdpraktik i skolan (Johansson, 2002 och dels inom forskningsprojektet Kommunikation och lärande i slöjdpraktiker, (”Komolär-projektet”, under 2005−2010 (Lindström, Borg, Johansson & Lindberg, 2003.Att insamla empiri i autentiska slöjdmiljöer är av intresse då lärandesituationer kan synliggöras när elever med hjälp av material och redskap arbetar med att tillverka artefakter. Utifrån detaljerade analyser av slöjdaktiviteter går det att upptäcka det som utspelar sig och möjligheter ges att uppfatta något annat jämfört med vad man kan tro känna väl eller ha förenklade och till och med felaktiga uppfattningar om. Videoobservationer möjliggör att antaganden istället görs på empiriskt grundat datamaterial. Med risk att videofilma och analysera det man tror sig veta och söka har forskningsprojektens insamlingar mer förutsättningslöst arbetat efter vad och hur elever och lärare gör i slöjdpraktik och vad man får veta när slöjdaktiviteter analyseras mer ingående. Videomaterialen har analyserats både på en mer övergripande nivå och detaljerat med hjälp av mikroanalyser. Därefter har lärandet synliggjorts och beskrivits bland annat i teman för att visa hur personerna är resurser för varandra och hur lärandet utvecklas genom olika språkanvändning och med slöjdpraktikens fysiska redskap och material.Sökord: metod, slöjd, klassrumsforskning, videoetnografi, mikroanalysURN:NBN:no-29955

Karlstads universitet - Ut i skogen, vad ska jag dit och göra? : En rapport om skapandet av ett unikt monterkoncept

OpenAIRE

Bergman, Karin; Jernberg, Jonna

2012-01-01

Sammanfattning Mässor förekom som fenomen redan under medeltiden och har allt sedan dess använts som en kanal för försäljning och marknadsföring. Idag tävlar företag och organisationer om mässbesökares uppmärksamhet genom att skapa attraktiva montrar med vinnande koncept som ska locka människor och få dem att lägga företagsnamnet på minnet. Detta är vad Karlstads universitet haft i åtanke då de utformat beskrivningen till detta projekt. Bakgrunden till projektet är att universitetet finns r...

Noliktavu vadības sistēmas (WMS) ieviešana un ieviešanas rezultātu analīze loģistikas uzņēmumā AS ,,Dominante Loģistikas Sistēma

OpenAIRE

Morozovs, Gļebs

2010-01-01

Darbā „Noliktavu vadības sistēmas (WMS) ieviešana un ieviešanas rezultātu analīze loģistikas uzņēmumā AS „Dominante Loģistikas Sistēma„ tiek pētīta noliktavu vadības sistēmas ievešanas ietekme uz loģistikas uzņēmumu. Darbā izpētīts loģistikas saturs un funkcionālās sfēra, aplūkoti noliktavu un transporta loģistika pamatprincipi un mijiedarbība, analizētas loģistikas attīstības tendences un loma Latvijas tautsaimniecība. Izpētīti noliktavu un transporta loģistikas instrumenti, raksturota infor...

Voice Activity Detection. Fundamentals and Speech Recognition System Robustness

OpenAIRE

Ramirez, J.; Gorriz, J. M.; Segura, J. C.

2007-01-01

This chapter has shown an overview of the main challenges in robust speech detection and a review of the state of the art and applications. VADs are frequently used in a number of applications including speech coding, speech enhancement and speech recognition. A precise VAD extracts a set of discriminative speech features from the noisy speech and formulates the decision in terms of well defined rule. The chapter has summarized three robust VAD methods that yield high speech/non-speech discri...

Vitamin A deficiency impairs adaptive B and T cell responses to a prototype monovalent attenuated human rotavirus vaccine and virulent human rotavirus challenge in a gnotobiotic piglet model.

Directory of Open Access Journals (Sweden)

Kuldeep S Chattha

Full Text Available Rotaviruses (RV are a major cause of gastroenteritis in children. Widespread vitamin A deficiency is associated with reduced efficacy of vaccines and higher incidence of diarrheal infections in children in developing countries. We established a vitamin A deficient (VAD gnotobiotic piglet model that mimics subclinical vitamin A deficiency in children to study its effects on an oral human rotavirus (HRV vaccine and virulent HRV challenge. Piglets derived from VAD and vitamin A sufficient (VAS sows were orally vaccinated with attenuated HRV or mock, with/without supplemental vitamin A and challenged with virulent HRV. Unvaccinated VAD control piglets had significantly lower hepatic vitamin A, higher severity and duration of diarrhea and HRV fecal shedding post-challenge as compared to VAS control pigs. Reduced protection coincided with significantly higher innate (IFNα cytokine and CD8 T cell frequencies in the blood and intestinal tissues, higher pro-inflammatory (IL12 and 2-3 fold lower anti-inflammatory (IL10 cytokines, in VAD compared to VAS control pigs. Vaccinated VAD pigs had higher diarrhea severity scores compared to vaccinated VAS pigs, which coincided with lower serum IgA HRV antibody titers and significantly lower intestinal IgA antibody secreting cells post-challenge in the former groups suggesting lower anamnestic responses. A trend for higher serum HRV IgG antibodies was observed in VAD vs VAS vaccinated groups post-challenge. The vaccinated VAD (non-vitamin A supplemented pigs had significantly higher serum IL12 (PID2 and IFNγ (PID6 compared to vaccinated VAS groups suggesting higher Th1 responses in VAD conditions. Furthermore, regulatory T-cell responses were compromised in VAD pigs. Supplemental vitamin A in VAD pigs did not fully restore the dysregulated immune responses to AttHRV vaccine or moderate virulent HRV diarrhea. Our findings suggest that that VAD in children in developing countries may partially contribute to more

Graph theoretical analysis of EEG effective connectivity in vascular dementia patients during a visual oddball task.

Science.gov (United States)

Wang, Chao; Xu, Jin; Zhao, Songzhen; Lou, Wutao

2016-01-01

The study was dedicated to investigating the change in information processing in brain networks of vascular dementia (VaD) patients during the process of decision making. EEG was recorded from 18 VaD patients and 19 healthy controls when subjects were performing a visual oddball task. The whole task was divided into several stages by using global field power analysis. In the stage related to the decision-making process, graph theoretical analysis was applied to the binary directed network derived from EEG signals at nine electrodes in the frontal, central, and parietal regions in δ (0.5-3.5Hz), θ (4-7Hz), α1 (8-10Hz), α2 (11-13Hz), and β (14-30Hz) frequency bands based on directed transfer function. A weakened outgoing information flow, a decrease in out-degree, and an increase in in-degree were found in the parietal region in VaD patients, compared to healthy controls. In VaD patients, the parietal region may also lose its hub status in brain networks. In addition, the clustering coefficient was significantly lower in VaD patients. Impairment might be present in the parietal region or its connections with other regions, and it may serve as one of the causes for cognitive decline in VaD patients. The brain networks of VaD patients were significantly altered toward random networks. The present study extended our understanding of VaD from the perspective of brain functional networks, and it provided possible interpretations for cognitive deficits in VaD patients. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Relationship between vitamin A deficiency and the thyroid axis in clinically stable patients with liver cirrhosis related to hepatitis C virus.

Science.gov (United States)

El-Eshmawy, Mervat M; Arafa, Mona M; Elzehery, Rasha R; Elhelaly, Rania M; Elrakhawy, Mohamed M; El-Baiomy, Azza A

2016-09-01

Vitamin A deficiency (VAD) and altered thyroid function are commonly encountered in patients with liver cirrhosis. The link between vitamin A metabolism and thyroid function has been previously identified. The aim of this study was to explore the association between VAD and the thyroid axis in clinically stable patients with cirrhosis related to hepatitis C virus (HCV). One hundred and twelve patients with clinically stable HCV-related cirrhosis and 56 healthy controls matched for age, sex, and socioeconomic status were recruited for this study. Vitamin A status, liver function, thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), reverse triiodothyronine (rT3), anti-thyroid peroxidase antibodies (anti-TPO), and thyroid volume were evaluated. The prevalence of VAD among patients with HCV-related cirrhosis was 62.5% compared with 5.4% among controls (P vitamin A status: VAD and normal vitamin A. Patients with VAD had significantly lower vitamin A intake and serum albumin and higher serum bilirubin, FT4, FT3, and TSH than patients with normal vitamin A status. Multiple logistic regression analysis revealed that VAD was associated with Child-Pugh score (β = 0.11, P = 0.05) and TSH (β = -1.63, P = 0.02) independently of confounding variables. We conclude that VAD may be linked to central hyperthyroidism in patients with clinically stable HCV-related liver cirrhosis.

Using medical imaging for the detection of adverse events ("incidents") during the utilization of left ventricular assist devices in adult patients with advanced heart failure.

Science.gov (United States)

Kaufmann, Friedrich; Krabatsch, Thomas

2016-05-01

Ventricular assist devices (VAD) are used for mechanical support of the terminally failing heart. Failure of these life supporting systems can be fatal. Early and reliable detection of any upcoming problems is mandatory and is crucial for the outcome. Medical imaging methods are described within this review, which are not only essential for diagnosis of typically VAD-related complications but also for the detection or verification of technical issues. Within this review the utilization of medical imaging equipment for the diagnosis of technical malfunctions or damages of implanted system components is discussed. A newly developed specialized acoustic imaging method for pump thrombosis detection will also be described along with the most common VAD-related medical complications and their respective imaging methods and the limitations induced by the use of the VAD-system.

Lack of association between PRNP 1368 polymorphism and Alzheimer's disease or vascular dementia

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Jeong Byung-Hoon

2009-04-01

Full Text Available Abstract Background Polymorphisms of the prion protein gene (PRNP at codons 129 and 219 play an important role in the susceptibility to Creutzfeldt-Jakob disease (CJD, and might be associated with other neurodegenerative disorders. Several recent reports indicate that polymorphisms outside the coding region of PRNP modulate the expression of prion protein and are associated with sporadic CJD, although other studies failed to show an association. These reports involved the polymorphism PRNP 1368 which is located upstream from PRNP exon 1. In a case-controlled protocol, we assessed the possible association between the PRNP 1368 polymorphism and either Alzheimer's disease (AD or vascular dementia (VaD. Methods To investigate whether the PRNP 1368 polymorphism is associated with the occurrence of AD or VaD in the Korean population, we compared the genotype, allele, and haplotype frequencies of the PRNP 1368 polymorphism in 152 AD patients and 192 VaD patients with frequencies in 268 healthy Koreans. Results and conclusion Significant differences in genotype, allele and haplotype frequencies of PRNP 1368 polymorphism were not observed between AD and normal controls. There were no significant differences in the genotype and allele frequencies of the PRNP 1368 polymorphism between Korean VaD patients and normal controls. However, in the haplotype analysis, haplotype Ht5 was significantly over-represented in Korean VaD patients. This was the first genetic association study of a polymorphism outside the coding region of PRNP in relation to AD and VaD.

Multichannel linear descriptors analysis for event-related EEG of vascular dementia patients during visual detection task.

Science.gov (United States)

Lou, Wutao; Xu, Jin; Sheng, Hengsong; Zhao, Songzhen

2011-11-01

Multichannel EEG recorded in a task condition could contain more information about cognition. However, that has not been widely investigated in the vascular-dementia (VaD)- related studies. The purpose of this study was to explore the differences of brain functional states between VaD patients and normal controls while performing a detection task. Three multichannel linear descriptors, i.e. spatial complexity (Ω), field strength (Σ) and frequency of field changes (Φ), were applied to analyse four frequency bands (delta, theta, alpha and beta) of multichannel event-related EEG signals for 12 VaD patients (mean age ± SD: 69.25 ± 10.56 years ; MMSE score ± SD: 22.58 ± 4.42) and 12 age-matched healthy subjects (mean age ± SD: 67.17 ± 5.97 years ; MMSE score ± SD: 29.08 ± 0.9). The correlations between the three measures and MMSE scores were also analysed. VaD patients showed a significant higher Ω value in the delta (p = 0.013) and theta (p = 0.021) frequency bands, a lower Σ value (p = 0.011) and a higher Φ (p = 0.008) value in the delta frequency band compared with normal controls. The MMSE scores were negatively correlated with the Ω (r = -0.52, p = 0.01) and Φ (r = -0.47, p = 0.02) values in the delta frequency band. The results indicated the VaD patients presented a reduction of synchronization in the slow frequency band during target detection, and suggested more neurons might be activated in VaD patients compared with normal controls. The Ω and Φ measures in the delta frequency band might be used to evaluate the degree of cognitive dysfunction. The multichannel linear descriptors are promising measures to reveal the differences in brain functions between VaD patients and normal subjects, and could potentially be used to evaluate the degree of cognitive dysfunction in VaD patients. Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Efficacy Of Rivastigmine And Donepezil On Cognitive Impairment Of Vascular Dementia - Some Preliminary Observations

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Jha S

2004-01-01

Full Text Available Background: Vascular Dementia (VaD is common, global, disabling and a rather neglected, age related dementia. It is important to identify and treat it since cognitive impairment produces dysfunction in occupational and social life. Moreso, due to increase in geriatric population, incidence and prevalence of VaD is also increasing. Aim: We share our observations on efficacy of Rivastigmine and Donepezil (drugs advocated for improving cognition in dementia in patients of VaD. Material and Method: This was a non-randomized study based on clinical evaluation. We selected 53 patients suffering from VaD (as per clinical and radiological criteria. Their age range was 55-78 years (mean 65.3 + 6.2 yrs. Clinical, biochemical and radiological (Cranial CT and MRI evaluation was done to establish etiology. Cognition was measured using modified Mini Mental State Examination (MMSE which was repeated 2 times, at interval of 3 months. We observed the role of Rivastigmine in 14 and Donepezil in 19 patients of VaD. The change in MMSE score was compared with 20 control patients of VaD. The associated risk factors like hypertension, diabetes, hyperlipidemia etc. were managed. Acetyl Salicylic Acid (ASA in dose of 150mg/day was given as an antiplatelet agent to all 53 patients in this study. Results: At end of study, no statistically significant improvement was observed in MMSE score in any of the 53 patients. Improvement in MMSE score (though statistically insignificant was observed with Rivastigmine in 11 and with Donepezil in 14 patients. Progressive decline in MMSE score was observed in 14 (70% control patients of VaD who did not receive rivastigmine or donepezil. Conclusion - Rivastigmine and Donepezil are beneficial in halting deterioration of dementia in patients suffering from VaD.

Semantic representation of CDC-PHIN vocabulary using Simple Knowledge Organization System.

Science.gov (United States)

Zhu, Min; Mirhaji, Parsa

2008-11-06

PHIN Vocabulary Access and Distribution System (VADS) promotes the use of standards based vocabulary within CDC information systems. However, the current PHIN vocabulary representation hinders its wide adoption. Simple Knowledge Organization System (SKOS) is a W3C draft specification to support the formal representation of Knowledge Organization Systems (KOS) within the framework of the Semantic Web. We present a method of adopting SKOS to represent PHIN vocabulary in order to enable automated information sharing and integration.

76 FR 36548 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

Science.gov (United States)

2011-06-22

... information related to the humanitarian device exemption for the Berlin Heart EXCOR Pediatric Ventricular Assist Device (VAD) sponsored by Berlin Heart, Inc. The Berlin Heart EXCOR Pediatric VAD device is a..., please contact AnnMarie Williams, Conference Management Staff, at 301-796-5966, at least 7 days in...

Experience of a patient with an extracorporeal ventricular assist system who participated in a sleepover program.

Science.gov (United States)

Gon, Shigeyoshi; Suematsu, Yoshihito; Morizumi, Sei; Shimizu, Tsuyoshi

2011-09-01

A 19-year-old woman suffered fulminant myocarditis owing to a mycoplasma infection and was inserted with an intra-aortic balloon pump and a percutaneous cardiopulmonary support. Antibiotics and gamma globulin were administered, however, the patient's cardiac function did not recover, and the TOYOBO ventricular assist device (VAD) was implanted. She had rehabilitation training such as maintaining a standing position at the bedside and walking in the hospital, and a hospital outing program to a family restaurant was conducted two times with the VAD. The patient wished to attend the coming-of-age ceremony in Tachikawa city, which is 3 h away from our hospital by car. Therefore, we planned the program including a night stay at her home. The patient and her family fully understood the risks and wished to participate in the sleepover program. In preparing for the sleepover, the patient and her family learned to operate the VAD, and she was able to move to the lavatory and through the house with the help of only her family. A physician and a clinical engineer stayed at her house for infusion of antibiotics and management of sudden changes. There was no adverse event. In Japan, the community support of patients with VAD is not yet established, and we hope that our experience becomes a help to support return to society for patients with VAD.

Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death.

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Benoît Meslin

Full Text Available Activation of proteolytic cell death pathways may circumvent drug resistance in deadly protozoan parasites such as Plasmodium falciparum and Leishmania. To this end, it is important to define the cell death pathway(s in parasites and thus characterize proteases such as metacaspases (MCA, which have been reported to induce cell death in plants and Leishmania parasites. We, therefore, investigated whether the cell death function of MCA is conserved in different protozoan parasite species such as Plasmodium falciparum and Leishmania major, focusing on the substrate specificity and functional role in cell survival as compared to Saccharomyces cerevisae. Our results show that, similarly to Leishmania, Plasmodium MCA exhibits a calcium-dependent, arginine-specific protease activity and its expression in yeast induced growth inhibition as well as an 82% increase in cell death under oxidative stress, a situation encountered by parasites during the host or when exposed to drugs such as artemisins. Furthermore, we show that MCA cell death pathways in both Plasmodium and Leishmania, involve a z-VAD-fmk inhibitable protease. Our data provide evidence that MCA from both Leishmania and Plasmodium falciparum is able to induce cell death in stress conditions, where it specifically activates a downstream enzyme as part of a cell death pathway. This enzymatic activity is also induced by the antimalarial drug chloroquine in erythrocytic stages of Plasmodium falciparum. Interestingly, we found that blocking parasite cell death influences their drug sensitivity, a result which could be used to create therapeutic strategies that by-pass drug resistance mechanisms by acting directly on the innate pathways of protozoan cell death.

Far-Field Voice Activity Detection and Its Applications in Adverse Acoustic Environments

DEFF Research Database (Denmark)

Petsatodis, Theodoros

2012-01-01

-sided Gamma distribution. The increased adaptability of the system along with the encapsulated adaptive threshold allows the system to perform remarkably under adverse complex phenomena. Following recent technological trends, of incorporating microphone arrays in numerous commercial applications (eg. mobile...... phones, VOIP terminals) and research environments (smart rooms), a multiple microphone VAD is also considered. The system processes signals captured by far-field sensors in order to integrate spatial information in addition to the frequency content available at a single sensor. The core of the system......-modality of speech production, a simple visual-VAD is also developed to examine performance enhancement when fusing audio and video information. In the final part of the work, applications of VAD in the context of integration with other signal processing systems are also considered. Performance benefits of combining...

Modernization of control system using the digital control system

International Nuclear Information System (INIS)

Carrasco, J. A.; Fernandez, L.; Jimenez, A.

2002-01-01

Nowadays, all plant automation tendencies are based on the use of Digital Control System. In big industrial plants the control systems employed are Distributed Control Systems (DCS). The addition of these systems in nuclear power plants,implies an important adaptation process, because most of them were installed using analog control systems. This paper presents the objectives and the first results obtained, in a modernization project, focused in obtaining an engineering platform for making test and analysis of changes prior to their implementation in a nuclear plant. Modernization, Upgrade, DCS, Automation, Simulation, Training. (Author)

Vitamin A deficiency alters the pulmonary parenchymal elastic modulus and elastic fiber concentration in rats

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Holmes Amey J

2005-07-01

Full Text Available Abstract Background Bronchial hyperreactivity is influenced by properties of the conducting airways and the surrounding pulmonary parenchyma, which is tethered to the conducting airways. Vitamin A deficiency (VAD is associated with an increase in airway hyperreactivity in rats and a decrease in the volume density of alveoli and alveolar ducts. To better define the effects of VAD on the mechanical properties of the pulmonary parenchyma, we have studied the elastic modulus, elastic fibers and elastin gene-expression in rats with VAD, which were supplemented with retinoic acid (RA or remained unsupplemented. Methods Parenchymal mechanics were assessed before and after the administration of carbamylcholine (CCh by determining the bulk and shear moduli of lungs that that had been removed from rats which were vitamin A deficient or received a control diet. Elastin mRNA and insoluble elastin were quantified and elastic fibers were enumerated using morphometric methods. Additional morphometric studies were performed to assess airway contraction and alveolar distortion. Results VAD produced an approximately 2-fold augmentation in the CCh-mediated increase of the bulk modulus and a significant dampening of the increase in shear modulus after CCh, compared to vitamin A sufficient (VAS rats. RA-supplementation for up to 21 days did not reverse the effects of VAD on the elastic modulus. VAD was also associated with a decrease in the concentration of parenchymal elastic fibers, which was restored and was accompanied by an increase in tropoelastin mRNA after 12 days of RA-treatment. Lung elastin, which was resistant to 0.1 N NaOH at 98°, decreased in VAD and was not restored after 21 days of RA-treatment. Conclusion Alterations in parenchymal mechanics and structure contribute to bronchial hyperreactivity in VAD but they are not reversed by RA-treatment, in contrast to the VAD-related alterations in the airways.

Outflow monitoring of a pneumatic ventricular assist device using external pressure sensors.

Science.gov (United States)

Kang, Seong Min; Her, Keun; Choi, Seong Wook

2016-08-25

In this study, a new algorithm was developed for estimating the pump outflow of a pneumatic ventricular assist device (p-VAD). The pump outflow estimation algorithm was derived from the ideal gas equation and determined the change in blood-sac volume of a p-VAD using two external pressure sensors. Based on in vitro experiments, the algorithm was revised to consider the effects of structural compliance caused by volume changes in an implanted unit, an air driveline, and the pressure difference between the sensors and the implanted unit. In animal experiments, p-VADs were connected to the left ventricles and the descending aorta of three calves (70-100 kg). Their outflows were estimated using the new algorithm and compared to the results obtained using an ultrasonic blood flow meter (UBF) (TS-410, Transonic Systems Inc., Ithaca, NY, USA). The estimated and measured values had a Pearson's correlation coefficient of 0.864. The pressure sensors were installed at the external controller and connected to the air driveline on the same side as the external actuator, which made the sensors easy to manage.

Imaging of muscarinic acetylcholine receptors using (+)N-[11C]methyl-3-piperidyl benzilate (11C-3NMPB) in vascular dementia and Alzheimer's disease

International Nuclear Information System (INIS)

Saito, Hirohiko

2006-01-01

In order to clarify the integrity of muscarinic acetylcholine receptor (mAChR) in vascular dementia (VaD) and Alzheimer's disease (AD), PET imaging with (+) N-[ 11 C]methyl-3-piperidyl benzilate ( 11 C-3NMPB) was performed in 12 patients with VaD, 11 patients with AD, and 7 normal controls (NC group). The mAChR binding was compared by the ratios compared with the cerebellum which were calculated from the regions of interest (ROI), and by three-dimensional statistic analysis. Compared with the NC group, mAChR was not significantly reduced in any ROI in AD patients. In those with VaD due to cortical lesions, mAChR was reduced in the infarcted areas. On the other hand, mAChR was significantly reduced in the thalamus and anterior cingulated gyrus, but not in other cerebral cortices in patients with VaD due to subcortical lesions. Accordingly, it is suggested that the mAChR is preserved in the cerebral cortices in patients with VaD due to subcortical lesions as well as in AD patients. (author)

Ventricular Assist Device implant (AB 5000 prototype cannula: In vitro assessment of MRI issues at 3-Tesla

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Valencerina Samuel

2008-05-01

Full Text Available Abstract Purpose To evaluate MRI issues at 3-Tesla for a ventricular assist device (VAD. Methods The AB5000 Ventricle with a prototype Nitinol wire-reinforced In-Flow Cannula and Out-Flow Cannula attached (Abiomed, Inc., Danvers, MA was evaluated for magnetic field interactions, heating, and artifacts at 3-Tesla. MRI-related heating was assessed with the device in a gelled-saline-filled, head/torso phantom using a transmit/received RF body coil while performing MRI at a whole body averaged SAR of 3-W/kg for 15-min. Artifacts were assessed for the main metallic component of this VAD (atrial cannula using T1-weighted, spin echo and gradient echo pulse sequences. Results The AB5000 Ventricle with the prototype In-Flow Cannula and Out-Flow Cannula attached showed relatively minor magnetic field interactions that will not cause movement in situ. Heating was not excessive (highest temperature change, +0.8°C. Artifacts may create issues for diagnostic imaging if the area of interest is in the same area or close to the implanted metallic component of this VAD (i.e., the venous cannula. Conclusion The results of this investigation demonstrated that it would be acceptable for a patient with this VAD (AB5000 Ventricle with a prototype Nitinol wire-reinforced In-Flow Cannula and Out-Flow Cannula attached to undergo MRI at 3-Tesla or less. Notably, it is likely that the operation console for this device requires positioning a suitable distance (beyond the 100 Gauss line or in the MR control room from the 3-Tesla MR system to ensure proper function of the VAD.

Simulation of Ventricular, Cavo-Pulmonary, and Biventricular Ventricular Assist Devices in Failing Fontan.

Science.gov (United States)

Di Molfetta, Arianna; Amodeo, Antonio; Fresiello, Libera; Trivella, Maria Giovanna; Iacobelli, Roberta; Pilati, Mara; Ferrari, Gianfranco

2015-07-01

Considering the lack of donors, ventricular assist devices (VADs) could be an alternative to heart transplantation for failing Fontan patients, in spite of the lack of experience and the complex anatomy and physiopathology of these patients. Considering the high number of variables that play an important role such as type of Fontan failure, type of VAD connection, and setting (right VAD [RVAD], left VAD [LVAD], or biventricular VAD [BIVAD]), a numerical model could be useful to support clinical decisions. The aim of this article is to develop and test a lumped parameter model of the cardiovascular system simulating and comparing the VAD effects on failing Fontan. Hemodynamic and echocardiographic data of 10 Fontan patients were used to simulate the baseline patients' condition using a dedicated lumped parameter model. Starting from the simulated baseline and for each patient, a systolic dysfunction, a diastolic dysfunction, and an increment of the pulmonary vascular resistance were simulated. Then, for each patient and for each pathology, the RVAD, LVAD, and BIVAD implantations were simulated. The model can reproduce patients' baseline well. In the case of systolic dysfunction, the LVAD unloads the single ventricle and increases the cardiac output (CO) (35%) and the arterial systemic pressure (Pas) (25%). With RVAD, a decrement of inferior vena cava pressure (Pvci) (39%) was observed with 34% increment of CO, but an increment of the single ventricle external work (SVEW). With the BIVAD, an increment of Pas (29%) and CO (37%) was observed. In the case of diastolic dysfunction, the LVAD increases CO (42%) and the RVAD decreases the Pvci, while both increase the SVEW. In the case of pulmonary vascular resistance increment, the highest CO (50%) and Pas (28%) increment is obtained with an RVAD with the highest decrement of Pvci (53%) and an increment of the SVEW but with the lowest VAD power consumption. The use of numerical models could be helpful in this innovative

Integrated control systems

International Nuclear Information System (INIS)

Smith, D.J.

1991-01-01

This paper reports that instrument manufacturers must develop standard network interfaces to pull together interrelated systems such as automatic start-up, optimization programs, and online diagnostic systems. In the past individual control system manufacturers have developed their own data highways with proprietary hardware and software designs. In the future, electric utilities will require that future systems, irrespective of manufacturer, should be able to communicate with each other. Until now the manufactures of control systems have not agreed on the standard high-speed data highway system. Currently, the Electric Power Research Institute (EPRI), in conjunction with several electric utilities and equipment manufactures, is working on developing a standard protocol for communicating between various manufacturers' control systems. According to N. Michael of Sargent and Lundy, future control room designs will require that more of the control and display functions be accessible from the control room through CRTs. There will be less emphasis on traditional hard-wired control panels

Reactor control system. PWR

International Nuclear Information System (INIS)

2009-01-01

At present, 23 units of PWR type reactors have been operated in Japan since the start of Mihama Unit 1 operation in 1970 and various improvements have been made to upgrade operability of power stations as well as reliability and safety of power plants. As the share of nuclear power increases, further improvements of operating performance such as load following capability will be requested for power stations with more reliable and safer operation. This article outlined the reactor control system of PWR type reactors and described the control performance of power plants realized with those systems. The PWR control system is characterized that the turbine power is automatic or manually controlled with request of the electric power system and then the nuclear power is followingly controlled with the change of core reactivity. The system mainly consists of reactor automatic control system (control rod control system), pressurizer pressure control system, pressurizer water level control system, steam generator water level control system and turbine bypass control system. (T. Tanaka)

BSF control system

International Nuclear Information System (INIS)

Irie, Y.; Ishii, K.; Ninomiya, S.; Sasaki, H.; Sakai, I.

1982-08-01

The booster synchrotron utilization facility (BSF) is a facility which utilizes the four fifths of available beam pulses from the KEK booster synchrotron. The BSF control system includes the beam line control, interactions with the PS central control room and the experimental facilities, and the access control system. A brief description of the various components in the control system is given. (author)

Vascular dementia: Facts and controversies

Directory of Open Access Journals (Sweden)

Pavlović Aleksandra

2013-01-01

Full Text Available Vascular dementia (VaD is the second most frequent dementia after Alzheimer’s disease, and is diagnosed during lifetime in 20% of demented patients. Five­year survival rate in VaD is 39%, while it is estimated to be 75% in healthy persons of the same age. It is therefore important to make correct diagnosis of VaD early in the course of the disease. Risk factors for VaD are identical to stroke risk factors, and there are significant possibilities for the prevention of vascular cognitive decline. Cognitive decline develops acutely or step­by­step within three months after stroke, but more gradual progression of intellectual decline is also possible. Neurological examination can reveal pyramidal and extrapyramidal signs, pseudobulbar palsy, gait disturbance and urinary incontinence. Neuropsychological profile comprises the loss of cognitive set shifting, decline in word fluency, verbal learning difficulties, perseverations, difficulties in complex figure copying, and in patients with cortically located lesions also problems with speech and praxia. The basis of the diagnosis is, besides history, neurological examination and neuropsychological assessment, computed tomography and/ or magnetic resonance brain imaging. Vascular risk factors control is the most important measure in VaD prevention. Modern guidelines for the treatment of cognitive decline in VaD emphasize that donepezil can be useful in the improvement of cognitive status at the level of Class IIa recommendation at the level of evidence A, while memantine may be useful in patients with mixed VaD and Alzheimer’s disease dementia. [Projekat Ministarstva nauke Republike Srbije, br. 175022 i br. 175033

The Ventricular Assist Device in the Life of the Child: A Phenomenological Pediatric Study.

Science.gov (United States)

van Manen, Michael A

2017-05-01

What is it like for a child to live with an artificial heart? The use of some medical therapies in children requires developmental considerations, is associated with psychosocial consequences, and calls for ethical sensitivities. A critical case is the ventricular assist device (VAD), a mechanical pump used to support the functioning of a failing heart. As a pediatric therapy, the device can be used as a temporary solution for poor heart function, a bridge to transplantation or recovery, or as a destination therapy. While the mechanical-technical operation of the VAD is well understood, the clinical-technical aspects of young people living with this device are largely unexplored. Drawing on interviews of school-aged children, the aim of this phenomenological study is to explore how a VAD may structure or condition a child's meaningful experience of their world outside the hospital. The driveline of an implanted VAD is the peripheral attachment, extruding through the skin to connect the controller-power supply. The materiality of the device may be interruptive, restrictive, and disturbing to the psycho-physical being and sense of self-identity of the child as a child. And while a child equipped with a VAD is not necessarily conspicuous among other children, the child may experience the device as an exposing presence, while living with the worry of a caregiver who takes on the role not simply of parent but of watchful health professional. A phenomenological understanding of the VAD should assist parents and caregiving health professionals knowing how to deal with specific issues arising in the life of the VAD child.

A cross-sectional study on thyroid status in North Indian elderly outpatients with dementia

Directory of Open Access Journals (Sweden)

Rachna Agarwal

2013-01-01

Full Text Available Background: Several population based studies have demonstrated an association between hypo-or hyperthyroidism and dementia in last two decades. As a consequence, thyroid stimulating hormone has become part of the screening laboratory test for dementia. Aim: The aim of the present study was to evaluate the association between thyroid function and Alzheimer′s disease (AD and vascular dementia (VaD and to determine the risk of AD and VaD in clinically euthyroid patients. Materials and Methods: A cross-sectional hospital based study was carried out in subjects diagnosed with AD/VaD and were assessed for thyroid status as routine screening test. Results: Free T3, free T4 and TSH were studied in 114 AD patients (mean age: 65 years, 35 VaD patients (mean age: 62 years and 105 control subjects (mean age: 62 years. In AD group, TSH levels were significantly lower than controls (P = 0.00 and for each unit increase in TSH level, the odds of having dementia decreased by 37.1%. No such relation was seen in VaD. Conclusion: The results suggest a consistent association of subclinical hyperthyroidism and AD.

Assessment of free and cued recall in Alzheimer's disease and vascular and frontotemporal dementia with 24-item Grober and Buschke test.

Science.gov (United States)

Cerciello, Milena; Isella, Valeria; Proserpi, Alice; Papagno, Costanza

2017-01-01

Alzheimer's disease (AD), vascular dementia (VaD) and frontotemporal dementia (FTD) are the most common forms of dementia. It is well known that memory deficits in AD are different from those in VaD and FTD, especially with respect to cued recall. The aim of this clinical study was to compare the memory performance in 15 AD, 10 VaD and 9 FTD patients and 20 normal controls by means of a 24-item Grober-Buschke test [8]. The patients' groups were comparable in terms of severity of dementia. We considered free and total recall (free plus cued) both in immediate and delayed recall and computed an Index of Sensitivity to Cueing (ISC) [8] for immediate and delayed trials. We assessed whether cued recall predicted the subsequent free recall across our patients' groups. We found that AD patients recalled fewer items from the beginning and were less sensitive to cueing supporting the hypothesis that memory disorders in AD depend on encoding and storage deficit. In immediate recall VaD and FTD showed a similar memory performance and a stronger sensitivity to cueing than AD, suggesting that memory disorders in these patients are due to a difficulty in spontaneously implementing efficient retrieval strategies. However, we found a lower ISC in the delayed recall compared to the immediate trials in VaD than FTD due to a higher forgetting in VaD.

Precision digital control systems

Science.gov (United States)

Vyskub, V. G.; Rozov, B. S.; Savelev, V. I.

This book is concerned with the characteristics of digital control systems of great accuracy. A classification of such systems is considered along with aspects of stabilization, programmable control applications, digital tracking systems and servomechanisms, and precision systems for the control of a scanning laser beam. Other topics explored are related to systems of proportional control, linear devices and methods for increasing precision, approaches for further decreasing the response time in the case of high-speed operation, possibilities for the implementation of a logical control law, and methods for the study of precision digital control systems. A description is presented of precision automatic control systems which make use of electronic computers, taking into account the existing possibilities for an employment of computers in automatic control systems, approaches and studies required for including a computer in such control systems, and an analysis of the structure of automatic control systems with computers. Attention is also given to functional blocks in the considered systems.

Association between air pollutants and dementia risk in the elderly.

Science.gov (United States)

Wu, Yun-Chun; Lin, Yuan-Chien; Yu, Hwa-Lung; Chen, Jen-Hau; Chen, Ta-Fu; Sun, Yu; Wen, Li-Li; Yip, Ping-Keung; Chu, Yi-Min; Chen, Yen-Ching

2015-06-01

The aging rate in Taiwan is the second highest in the world. As the population ages quickly, the prevalence of dementia increases rapidly. There are some studies that have explored the association between air pollution and cognitive decline, but the association between air pollution and dementia has not been directly evaluated. This was a case-control study comprising 249 Alzheimer's disease (AD) patients, 125 vascular dementia (VaD) patients, and 497 controls from three teaching hospitals in northern Taiwan from 2007 to 2010. Data of particulate matter Bayesian maximum entropy was used to estimate the individual exposure level of air pollutants, which was then tertiled for analysis. Conditional logistic regression models were used to estimate adjusted odds ratios (AORs) and 95% confidence intervals between the association of PM10 and ozone exposure with AD and VaD risk. The highest tertile of PM10 (≥49.23 μg/m(3)) or ozone (≥21.56 ppb) exposure was associated with increased AD risk (highest vs. lowest tertile of PM10: AOR = 4.17; highest vs. lowest tertile of ozone: AOR = 2.00). Similar finding was observed for VaD. The association with AD and VaD risk remained for the highest tertile PM10 exposure after stratification by APOE ɛ4 status and gender. Long-term exposure to the highest tertile of PM10 or ozone was significantly associated with an increased risk of AD and VaD.

Control system design method

Science.gov (United States)

Wilson, David G [Tijeras, NM; Robinett, III, Rush D.

2012-02-21

A control system design method and concomitant control system comprising representing a physical apparatus to be controlled as a Hamiltonian system, determining elements of the Hamiltonian system representation which are power generators, power dissipators, and power storage devices, analyzing stability and performance of the Hamiltonian system based on the results of the determining step and determining necessary and sufficient conditions for stability of the Hamiltonian system, creating a stable control system based on the results of the analyzing step, and employing the resulting control system to control the physical apparatus.

Incoherent control of locally controllable quantum systems

International Nuclear Information System (INIS)

Dong Daoyi; Zhang Chenbin; Rabitz, Herschel; Pechen, Alexander; Tarn, T.-J.

2008-01-01

An incoherent control scheme for state control of locally controllable quantum systems is proposed. This scheme includes three steps: (1) amplitude amplification of the initial state by a suitable unitary transformation, (2) projective measurement of the amplified state, and (3) final optimization by a unitary controlled transformation. The first step increases the amplitudes of some desired eigenstates and the corresponding probability of observing these eigenstates, the second step projects, with high probability, the amplified state into a desired eigenstate, and the last step steers this eigenstate into the target state. Within this scheme, two control algorithms are presented for two classes of quantum systems. As an example, the incoherent control scheme is applied to the control of a hydrogen atom by an external field. The results support the suggestion that projective measurements can serve as an effective control and local controllability information can be used to design control laws for quantum systems. Thus, this scheme establishes a subtle connection between control design and controllability analysis of quantum systems and provides an effective engineering approach in controlling quantum systems with partial controllability information.

Control systems engineering

CERN Document Server

Nise, Norman S

1995-01-01

This completely updated new edition shows how to use MATLAB to perform control-system calculations. Designed for the professional or engineering student who needs a quick and readable update on designing control systems, the text features a series of tightly focused examples that clearly illustrate each concept of designing control systems. Most chapters conclude with a detailed application from the two case studies that run throughout the book: an antenna asimuth control system and a submarine. The author also refers to many examples of design methods.

Discrete control systems

CERN Document Server

Okuyama, Yoshifumi

2014-01-01

Discrete Control Systems establishes a basis for the analysis and design of discretized/quantized control systemsfor continuous physical systems. Beginning with the necessary mathematical foundations and system-model descriptions, the text moves on to derive a robust stability condition. To keep a practical perspective on the uncertain physical systems considered, most of the methods treated are carried out in the frequency domain. As part of the design procedure, modified Nyquist–Hall and Nichols diagrams are presented and discretized proportional–integral–derivative control schemes are reconsidered. Schemes for model-reference feedback and discrete-type observers are proposed. Although single-loop feedback systems form the core of the text, some consideration is given to multiple loops and nonlinearities. The robust control performance and stability of interval systems (with multiple uncertainties) are outlined. Finally, the monograph describes the relationship between feedback-control and discrete ev...

Quantitative safety assessment of air traffic control systems through system control capacity

Science.gov (United States)

Guo, Jingjing

Quantitative Safety Assessments (QSA) are essential to safety benefit verification and regulations of developmental changes in safety critical systems like the Air Traffic Control (ATC) systems. Effectiveness of the assessments is particularly desirable today in the safe implementations of revolutionary ATC overhauls like NextGen and SESAR. QSA of ATC systems are however challenged by system complexity and lack of accident data. Extending from the idea "safety is a control problem" in the literature, this research proposes to assess system safety from the control perspective, through quantifying a system's "control capacity". A system's safety performance correlates to this "control capacity" in the control of "safety critical processes". To examine this idea in QSA of the ATC systems, a Control-capacity Based Safety Assessment Framework (CBSAF) is developed which includes two control capacity metrics and a procedural method. The two metrics are Probabilistic System Control-capacity (PSC) and Temporal System Control-capacity (TSC); each addresses an aspect of a system's control capacity. And the procedural method consists three general stages: I) identification of safety critical processes, II) development of system control models and III) evaluation of system control capacity. The CBSAF was tested in two case studies. The first one assesses an en-route collision avoidance scenario and compares three hypothetical configurations. The CBSAF was able to capture the uncoordinated behavior between two means of control, as was observed in a historic midair collision accident. The second case study compares CBSAF with an existing risk based QSA method in assessing the safety benefits of introducing a runway incursion alert system. Similar conclusions are reached between the two methods, while the CBSAF has the advantage of simplicity and provides a new control-based perspective and interpretation to the assessments. The case studies are intended to investigate the

Multifunctional particle-constituted microneedle arrays as cutaneous or mucosal vaccine adjuvant-delivery systems

Science.gov (United States)

Wang, Xueting; Wang, Ning; Li, Ning; Zhen, Yuanyuan; Wang, Ting

2016-01-01

ABSTRACT To overcome drawbacks of current injection vaccines, such as causing needle phobia, needing health professionals for inoculation, and generating dangerous sharps wastes, researchers have designed novel vaccines that are combined with various microneedle arrays (MAs), in particular, with the multifunctional particle-constructed MAs (MPMAs). MPMAs prove able to enhance vaccine stability through incorporating vaccine ingredients in the carrier, and can be painlessly inoculated by minimally trained workers or by self-administration, leaving behind no metal needle pollution while eliciting robust systemic and mucosal immunity to antigens, thanks to delivering vaccines to cutaneous or mucosal compartments enriched in professional antigen-presenting cells (APCs). Especially, MPMAs can be easily integrated with functional molecules fulfilling targeting vaccine delivery or controlling immune response toward a Th1 or Th2 pathway to generate desired immunity against pathogens. Herein, we introduce the latest research and development of various MPMAs which are a novel but promising vaccine adjuvant delivery system (VADS). PMID:27159879

Prenatal vitamin A deficiency impairs adaptive immune responses to pentavalent rotavirus vaccine (RotaTeq®) in a neonatal gnotobiotic pig model.

Science.gov (United States)

Kandasamy, Sukumar; Chattha, Kuldeep S; Vlasova, Anastasia N; Saif, Linda J

2014-02-07

Vitamin A deficiency (VAD) is associated with increased childhood mortality and morbidity in impoverished Asian and African countries, but the impact of VAD on rotavirus (RV) vaccine or infection is poorly understood. We assessed effects of gestational and dietary induced pre- and post-natal VAD and vitamin A supplementation on immune responses to a pentavalent rotavirus vaccine, RotaTeq(®) in a neonatal gnotobiotic pig model. Vaccine efficacy was assessed against virulent G1P[8] human rotavirus (HRV) challenge. VAD and vitamin A sufficient (VAS) piglets were derived from dietary VAD and VAS sows, respectively. VAD piglets had significantly lower levels of hepatic vitamin A compared to that of VAS piglets. RotaTeq(®)-vaccinated VAD piglets had 350-fold higher fecal virus shedding titers compared to vaccinated VAS piglets post-challenge. Only 25% of vaccinated non-vitamin A supplemented VAD piglets were protected against diarrhea compared with 100% protection rate in vaccinated non-supplemented VAS piglets post-challenge. Intestinal HRV specific immune responses were compromised in VAD piglets. Vaccinated VAD piglets had significantly lower ileal HRV IgG antibody secreting cell (ASC) responses (pre-challenge) and duodenal HRV IgA ASC responses (post-challenge) compared to vaccinated VAS piglets. Also, intestinal HRV IgA antibody titers were 11-fold lower in vaccinated VAD compared to vaccinated VAS piglets post-challenge. Persistently elevated levels of IL-8, a pro-inflammatory mediator, and lower IL-10 responses (anti-inflammatory) in vaccinated VAD compared to VAS piglets suggest more severe inflammatory responses in VAD piglets post-challenge. Moreover higher IFN-γ responses pre-challenge were observed in VAD compared to VAS piglets. The impaired vaccine-specific intestinal antibody responses and decreased immunoregulatory cytokine responses coincided with reduced protective efficacy of the RV vaccine against virulent HRV challenge in VAD piglets. In

Minicomputer controlled test system for process control and monitoring systems

International Nuclear Information System (INIS)

Worster, L.D.

A minicomputer controlled test system for testing process control and monitoring systems is described. This system, in service for over one year, has demonstrated that computerized control of such testing has a real potential for expanding the scope of the testing, improving accuracy of testing, and significantly reducing the time required to do the testing. The test system is built around a 16-bit minicomputer with 12K of memory. The system programming language is BASIC with the addition of assembly level routines for communication with the peripheral devices. The peripheral devices include a 100 channel scanner, analog-to-digital converter, visual display, and strip printer. (auth)

Systematic Design of a Magnetically Levitated Brushless DC Motor for a Reversible Rotary Intra-Aortic Blood Pump.

Science.gov (United States)

Wang, Yaxin; Logan, Thomas G; Smith, P Alex; Hsu, Po-Lin; Cohn, William E; Xu, Liping; McMahon, Richard A

2017-10-01

The IntraVAD is a miniature intra-aortic ventricular assist device (VAD) designed to work in series with the compromised left ventricle. A reverse-rotation control (RRc) mode has been developed to increase myocardial perfusion and reduce ventricular volume. The RRc mode includes forward rotation in systole and reverse rotation in diastole, which requires the IntraVAD to periodically reverse its rotational direction in synchrony with the cardiac cycle. This periodic reversal leads to changes in pressure force over the impeller, which makes the entire system less stable. To eliminate the mechanical wear of a contact bearing and provide active control over the axial position of the rotor, a miniature magnetically levitated bearing (i.e., the PM-Coil module) composed of two concentric permanent magnetic (PM) rings and a pair of coils-one on each side-was proposed to provide passive radial and active axial rotor stabilization. In the early design stage, the numerical finite element method (FEM) was used to optimize the geometry of the brushless DC (BLDC) motor and the maglev module, but constructing a new model each time certain design parameters were adjusted required substantial computation time. Because the design criteria for the module had to be modified to account for the magnetic force produced by the motor and for the hemodynamic changes associated with pump operation, a simplified analytic expression was derived for the expected magnetic forces. Suitable bearings could then be designed capable of overcoming these forces without repeating the complicated FEM simulation for the motor. Using this method at the initial design stage can inform the design of the miniature maglev BLDC motor for the proposed pulsatile axial-flow VAD. © 2017 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

The Ventricular Assist Device in the Life of the Child: A Phenomenological Pediatric Study

Science.gov (United States)

van Manen, Michael A.

2017-01-01

What is it like for a child to live with an artificial heart? The use of some medical therapies in children requires developmental considerations, is associated with psychosocial consequences, and calls for ethical sensitivities. A critical case is the ventricular assist device (VAD), a mechanical pump used to support the functioning of a failing heart. As a pediatric therapy, the device can be used as a temporary solution for poor heart function, a bridge to transplantation or recovery, or as a destination therapy. While the mechanical-technical operation of the VAD is well understood, the clinical-technical aspects of young people living with this device are largely unexplored. Drawing on interviews of school-aged children, the aim of this phenomenological study is to explore how a VAD may structure or condition a child’s meaningful experience of their world outside the hospital. The driveline of an implanted VAD is the peripheral attachment, extruding through the skin to connect the controller-power supply. The materiality of the device may be interruptive, restrictive, and disturbing to the psycho-physical being and sense of self-identity of the child as a child. And while a child equipped with a VAD is not necessarily conspicuous among other children, the child may experience the device as an exposing presence, while living with the worry of a caregiver who takes on the role not simply of parent but of watchful health professional. A phenomenological understanding of the VAD should assist parents and caregiving health professionals knowing how to deal with specific issues arising in the life of the VAD child. PMID:28682718

EU:s nya varumärkesdefinition : En utredning av vad borttagandet av kravet på grafisk återgivning kommer att innebära för möjligheten att registrera okonventionella varumärken

OpenAIRE

Fredriksson, Mathilda; Petersson, Frida

2017-01-01

Sedan det första steget togs mot en harmoniserad varumärkesrätt inom EU har grafisk återgivning varit ett krav vid registrering av varumärken, men kravet på grafisk återgivning försvinner i och med EU:s nya varumärkesreform. Syftet med denna uppsats är att belysa och utreda vad detta kommer att innebära för möjligheten att registrera okonventionella varumärken. Utredningen är inriktad på följande okonventionella varumärken: doftmärken, smakmärken, ljudmärken, känselmärken, rörelsemärken och h...

A national control system

International Nuclear Information System (INIS)

Larsson, A.

1975-01-01

An effective control of nuclear fissionable material is dependent on three different kinds of control, the industry - laboratory management, a national control system and an international safeguards system. The national systems of control differ greatly between various industrialized countries. Two principal reasons for fact can be mentioned. The type and the amounts for nuclear material may be different depending upon the stage of development of the nuclear industry in the country in question. Another reason may be that the country may wish to establish a very elaborate national system of control in order to minimize the IAEA control as much as possible. The two safeguards agreements between the Agency and Sweden on one hand and the Agency and Japan on the other hand can serve as examples for the understanding of the latitude of the IAEA safeguards system under NPT due to the influence of the national control system. If it thus is apparent that the national control system is strongly interrelated to the international safeguards system it is equally influenced by the control and accountancy systems which exist at the nuclear plants and development laboratories. A detailed study of national control systems and their relations to plant management control would fall outside the scope of this article. Some important features will however be examined. (author)

Voice acoustic patterns of patients diagnosed with vibroacoustic disease

Directory of Open Access Journals (Sweden)

Ana Mendes

2006-07-01

Full Text Available Background: Long-term low frequency noise exposure (LFN (≤ 500 Hz, including infrasound may lead to the development of vibroacoustic disease (VAD, a systemic pathology characterized by the abnormal growth of extra-cellular matrices. The respiratory system is a target for LFN. Fibrosis of the respiratory tract epithelia was observed in VAD patients through biopsy, and confirmed in animal models exposed to LFN. Voice acoustic analysis can detect vocal fold variations of mass, tension, muscular and neural activity. Frequency perturbation (jitter, amplitude perturbation (shimmer and harmonicto- noise ratio (HNR are used in the evaluation of the vocal function, and can be indicators of the presence and degree of severity of vocal pathology. Since the respiratory system is the energy source of the phonation process, this raises questions about the effects of VAD on voice production. The purpose of this study was to determine if voice acoustic parameters of VAD patients are different from normative data. Methods: Nine individuals (5 males and 4 females diagnosed with VAD were recorded performing spoken and sung tasks. The spoken tasks included sustaining vowels and fricatives. The sung tasks consisted of maximum phonational frequency range (MPFR. Voice acoustic parameters analysed were: fundamental frequency (F0, jitter, shimmer, HNR and temporal measures. Results: Compared with normative data, both males and females diagnosed with VAD exhibited increased F0, shimmer and HNR. Jitter, MPFR and one temporal measure were reduced. Conclusions: VAD individuals presented voice acoustic parameter differences in spectral, temporal and perturbation measures, which may be indicative of small morphological changes in the phonatory system. Resumo: Enquadramento: A exposição crónica ao ruído de baixa frequência (RBF (≤ 500 Hz, incluindo infra-sons pode conduzir ao desenvolvimento da doença vibroacústica (VAD �

Padrões acústicos da voz em indivíduos com a doença vibroacústica

Directory of Open Access Journals (Sweden)

Ana Mendes

2006-07-01

(VAD, a systemic pathology characterized by the abnormal growth of extra-cellular matrices. The respiratory system is a target for LFN. Fibrosis of the respiratory tract epithelia was observed in VAD patients through biopsy, and confirmed in animal models exposed to LFN. Voice acoustic analysis can detect vocal fold variations of mass, tension, muscular and neural activity. Frequency perturbation (jitter, amplitude perturbation (shimmer and harmonic-to-noise ratio (HNR are used in the evaluation of the vocal function, and can be indicators of the presence and degree of severity of vocal pathology. Since the respiratory system is the energy source of the phonation process, this raises questions about the effects of VAD on voice production. The purpose of this study was to determine if voice acoustic parameters of VAD patients are different from normative data. Methods: Nine individuals (5 males and 4 females diagnosed with VAD were recorded performing spoken and sung tasks. The spoken tasks included sustaining vowels and fricatives. The sung tasks consisted of maximum phonational frequency range (MPFR. Voice acoustic parameters analysed were: fundamental frequency (F0, jitter, shimmer, HNR and temporal measures. Results: Compared with normative data, both males and females diagnosed with VAD exhibited increased F0, shimmer and HNR. Jitter, MPFR and one temporal measure were reduced. Conclusions: VAD individuals presented voice acoustic parameter differences in spectral, temporal and perturbation measures, which may be indicative of small morphological changes in the phonatory system.Rev Port Pneumol 2006; XII (4: 375-382 Palavras-chave: Ruído de baixa frequência, infra-sons, shimmer, jitter, acústica da voz, cordas vocais, Key-words: Low frequency noise, infrasound, shimmer, jitter, voice acoustics, vocal folds

Use of Ventricular Assist Device in Univentricular Physiology: The Role of Lumped Parameter Models.

Science.gov (United States)

Di Molfetta, Arianna; Ferrari, Gianfranco; Filippelli, Sergio; Fresiello, Libera; Iacobelli, Roberta; Gagliardi, Maria G; Amodeo, Antonio

2016-05-01

Failing single-ventricle (SV) patients might benefit from ventricular assist devices (VADs) as a bridge to heart transplantation. Considering the complex physiopathology of SV patients and the lack of established experience, the aim of this work was to realize and test a lumped parameter model of the cardiovascular system, able to simulate SV hemodynamics and VAD implantation effects. Data of 30 SV patients (10 Norwood, 10 Glenn, and 10 Fontan) were retrospectively collected and used to simulate patients' baseline. Then, the effects of VAD implantation were simulated. Additionally, both the effects of ventricular assistance and cavopulmonary assistance were simulated in different pathologic conditions on Fontan patients, including systolic dysfunction, diastolic dysfunction, and pulmonary vascular resistance increment. The model can reproduce patients' baseline well. Simulation results suggest that the implantation of VAD: (i) increases the cardiac output (CO) in all the three palliation conditions (Norwood 77.2%, Glenn 38.6%, and Fontan 17.2%); (ii) decreases the SV external work (SVEW) (Norwood 55%, Glenn 35.6%, and Fontan 41%); (iii) increases the mean pulmonary arterial pressure (Pap) (Norwood 39.7%, Glenn 12.1%, and Fontan 3%). In Fontan circulation, with systolic dysfunction, the left VAD (LVAD) increases CO (35%), while the right VAD (RVAD) determines a decrement of inferior vena cava pressure (Pvci) (39%) with 34% increment of CO. With diastolic dysfunction, the LVAD increases CO (42%) and the RVAD decreases the Pvci. With pulmonary vascular resistance increment, the RVAD allows the highest CO (50%) increment with the highest decrement of Pvci (53%). The single ventricular external work (SVEW) increases (decreases) increasing the VAD speed in cavopulmonary (ventricular) assistance. Numeric models could be helpful in this challenging and innovative field to support patients and VAD selection to optimize the clinical outcome and personalize the therapy

Management of Control System Information SecurityI: Control System Patch Management

Energy Technology Data Exchange (ETDEWEB)

Quanyan Zhu; Miles McQueen; Craig Rieger; Tamer Basar

2011-09-01

The use of information technologies in control systems poses additional potential threats due to the frequent disclosure of software vulnerabilities. The management of information security involves a series of policy-making on the vulnerability discovery, disclosure, patch development and patching. In this paper, we use a system approach to devise a model to understand the interdependencies of these decision processes. In more details, we establish a theoretical framework for making patching decision for control systems, taking into account the requirement of functionability of control systems. We illustrate our results with numerical simulations and show that the optimal operation period of control systems given the currently estimated attack rate is roughly around a half a month.

Dynamic Systems and Control Engineering

International Nuclear Information System (INIS)

Kim, Jong Seok

1994-02-01

This book deals with introduction of dynamic system and control engineering, frequency domain modeling of dynamic system, temporal modeling of dynamic system, typical dynamic system and automatic control device, performance and stability of control system, root locus analysis, analysis of frequency domain dynamic system, design of frequency domain dynamic system, design and analysis of space, space of control system and digital control system such as control system design of direct digital and digitalization of consecutive control system.

Dynamic Systems and Control Engineering

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Seok

1994-02-15

This book deals with introduction of dynamic system and control engineering, frequency domain modeling of dynamic system, temporal modeling of dynamic system, typical dynamic system and automatic control device, performance and stability of control system, root locus analysis, analysis of frequency domain dynamic system, design of frequency domain dynamic system, design and analysis of space, space of control system and digital control system such as control system design of direct digital and digitalization of consecutive control system.

Hemodynamic Effects of Ventricular Assist Device Implantation on Norwood, Glenn, and Fontan Circulation: A Simulation Study.

Science.gov (United States)

Di Molfetta, Arianna; Amodeo, Antonio; Gagliardi, Maria G; Trivella, Maria G; Fresiello, Libera; Filippelli, Sergio; Toscano, Alessandra; Ferrari, Gianfranco

2016-01-01

The growing population of failing single-ventricle (SV) patients might benefit from ventricular assist device (VAD) support as a bridge to heart transplantation. However, the documented experience is limited to isolated case reports. Considering the complex and different physiopathology of Norwood, Glenn, and Fontan patients and the lack of established experience, the aim of this work is to realize and test a lumped parameter model of the cardiovascular system able to simulate SV hemodynamics and VAD implantation effects to support clinical decision. Hemodynamic and echocardiographic data of 30 SV patients (10 Norwood, 10 Glenn, and 10 Fontan) were retrospectively collected and used to simulate patients' baseline. Then, the effects of VAD implantation were simulated. Simulation results suggest that the implantation of VAD: (i) increases the cardiac output and the mean arterial systemic pressure in all the three palliation conditions (Norwood 77.2 and 19.7%, Glenn 38.6 and 32.2%, and Fontan 17.2 and 14.2%); (ii) decreases the SV external work (Norwood 55%, Glenn 35.6%, and Fontan 41%); (iii) decreases the pressure pulsatility index (Norwood 65.2%, Glenn 81.3%, and Fontan 64.8%); (iv) increases the pulmonary arterial pressure in particular in the Norwood circulation (Norwood 39.7%, Glenn 12.1% and Fontan 3%); and (v) decreases the atrial pressure (Norwood 2%, Glenn 10.6%, and Fontan 8.6%). Finally, the VAD work is lower in the Norwood circulation (30.4 mL·mm Hg) in comparison with Fontan (40.3 mL·mm Hg) and to Glenn (64.5 mL·mm Hg) circulations. The use of VAD in SV physiology could be helpful to bridge patients to heart transplantations by increasing the CO and unloading the SV with a decrement of the atrial pressure and the SV external work. The regulation of the pulmonary flow is challenging because the Pap is increased by the presence of VAD. The hemodynamic changes are different in the different SV palliation step. The use of numerical models

Automatic control systems engineering

International Nuclear Information System (INIS)

Shin, Yun Gi

2004-01-01

This book gives descriptions of automatic control for electrical electronics, which indicates history of automatic control, Laplace transform, block diagram and signal flow diagram, electrometer, linearization of system, space of situation, state space analysis of electric system, sensor, hydro controlling system, stability, time response of linear dynamic system, conception of root locus, procedure to draw root locus, frequency response, and design of control system.

The Potential of Integrating Provitamin A-Biofortified Maize in Smallholder Farming Systems to Reduce Malnourishment in South Africa

Directory of Open Access Journals (Sweden)

Mthokozisi K. Zuma

2018-04-01

Full Text Available Biofortification interventions have the potential to combat malnutrition. This review explored the use of provitamin A-biofortified maize (PVABM as a vitamin A deficiency (VAD reduction agricultural-based strategy. Maize has been identified as one of the key staple crops for biofortification to reduce hidden hunger in Africa. Most nutrition interventions have not been successful in reducing hunger because rural communities, who mainly rely on agriculture, have been indirectly excluded. The biofortification intervention proposed here aims to be an inclusive strategy, based on smallholder farming systems. Vitamin A is a micronutrient essential for growth, immune function, reproduction and vision, and its deficiency results in VAD. VAD is estimated to affect more than 250 million children in developing countries. In Africa, especially sub-Saharan Africa, maize is a staple food for rural communities, consumed by most household members. Due to carotenoids, PVABM presents an orange color. This color has been reported to lead to negative perceptions about PVABM varieties. The perceived agronomic traits of this maize by smallholder farmers have not been explored. Adoption and utilization of PVABM varieties relies on both acceptable consumer attributes and agronomic traits, including nutritional value. It is therefore important to assess farmers’ perceptions of and willingness to adopt the varieties, and the potential markets for PVABM maize. It is essential to establish on-farm trials and experiments to evaluate the response of PVABM under different climatic conditions, fertilizer levels and soils, and its overall agronomic potential. For the better integration of PVABM with smallholder farming systems, farmer training and workshops about PVABM should be part of any intervention. A holistic approach would enhance farmers’ knowledge about PVABM varieties and that their benefits out-compete other existing maize varieties.

Leisure activities, apolipoprotein E e4 status, and the risk of dementia.

Science.gov (United States)

Yang, Sheng-Ying; Weng, Pei-Hsuan; Chen, Jen-Hau; Chiou, Jeng-Min; Lew-Ting, Chih-Yin; Chen, Ta-Fu; Sun, Yu; Wen, Li-Li; Yip, Ping-Keung; Chu, Yi-Min; Chen, Yen-Ching

2015-12-01

Leisure activities have been associated with a decreased risk of dementia. However, to date, no study has explored how apolipoprotein E (ApoE) e4 status or vascular risk factors modified the association between leisure activities and dementia risks. This case-control study recruited patients (age ≥ 60 years) with Alzheimer's disease (AD; n = 292) and vascular dementia (VaD; n = 144) and healthy controls (n = 506) from three teaching hospitals in Taiwan between 2007 and 2010. Information on patient's leisure activities were obtained through a questionnaire. Conditional logistic regression models were used to assess the association of leisure activities and ApoE e4 status with the risk of dementia. High-frequency physical activity was associated with a decreased risk of AD [adjusted odds ratio (AOR) = 0.45], and the results become more evident among ApoE e4 carriers with AD (AOR = 0.30) and VaD (AOR = 0.26). Similar findings were observed for cognitive (AOR = 0.42) and social activities (AOR = 0.55) for AD. High-frequency physical, cognitive, and social activities were associated with a decreased risk of VaD (AOR = 0.29-0.60). Physical and social activities significantly interacted with each other on the risk of VaD (pinteraction = 0.04). Physical activity consistently protects against AD and VaD. Significant interactions were identified across different types of leisure activities in lowering dementia risk. Copyright © 2014. Published by Elsevier B.V.

CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients.

Science.gov (United States)

Skillbäck, Tobias; Delsing, Louise; Synnergren, Jane; Mattsson, Niklas; Janelidze, Shorena; Nägga, Katarina; Kilander, Lena; Hicks, Ryan; Wimo, Anders; Winblad, Bengt; Hansson, Oskar; Blennow, Kaj; Eriksdotter, Maria; Zetterberg, Henrik

2017-11-01

A connection between dementias and blood-brain barrier (BBB) dysfunction has been suggested, but previous studies have yielded conflicting results. We examined cerebrospinal fluid (CSF)/serum albumin ratio in a large cohort of patients diagnosed with Alzheimer's disease (AD, early onset [EAD, n = 130], late onset AD [LAD, n = 666]), vascular dementia (VaD, n = 255), mixed AD and VaD (MIX, n = 362), Lewy body dementia (DLB, n = 50), frontotemporal dementia (FTD, n = 56), Parkinson's disease dementia (PDD, n = 23), other dementias (other, n = 48), and dementia not otherwise specified (NOS, n = 271). We compared CSF/serum albumin ratio to 2 healthy control groups (n = 292, n = 20), between dementia diagnoses, and tested biomarker associations. Patients in DLB, LAD, VaD, MIX, other, and NOS groups had higher CSF/serum albumin ratio than controls. CSF/serum albumin ratio correlated with CSF neurofilament light in LAD, MIX, VaD, and other groups but not with AD biomarkers. Our data show that BBB leakage is common in dementias. The lack of association between CSF/serum albumin ratio and AD biomarkers suggests that BBB dysfunction is not inherent to AD but might represent concomitant cerebrovascular pathology. Copyright © 2017 Elsevier Inc. All rights reserved.

Control and automation systems

International Nuclear Information System (INIS)

Schmidt, R.; Zillich, H.

1986-01-01

A survey is given of the development of control and automation systems for energy uses. General remarks about control and automation schemes are followed by a description of modern process control systems along with process control processes as such. After discussing the particular process control requirements of nuclear power plants the paper deals with the reliability and availability of process control systems and refers to computerized simulation processes. The subsequent paragraphs are dedicated to descriptions of the operating floor, ergonomic conditions, existing systems, flue gas desulfurization systems, the electromagnetic influences on digital circuits as well as of light wave uses. (HAG) [de

The Total Artificial Heart in End-Stage Congenital Heart Disease.

Science.gov (United States)

Villa, Chet R; Morales, David L S

2017-01-01

The development of durable ventricular assist devices (VADs) has improved mortality rates and quality of life in patients with end stage heart failure. While the use of VADs has increased dramatically in recent years, there is limited experience with VAD implantation in patients with complex congenital heart disease (CHD), despite the fact that the number of patients with end stage CHD has grown due to improvements in surgical and medical care. VAD use has been limited in patients with CHD and end stage heart failure due to anatomic (systemic right ventricle, single ventricle, surgically altered anatomy, valve dysfunction, etc.) and physiologic constraints (diastolic dysfunction). The total artificial heart (TAH), which has right and left sided pumps that can be arranged in a variety of orientations, can accommodate the anatomic variation present in CHD patients. This review provides an overview of the potential use of the TAH in patients with CHD.

Control system design guide

Energy Technology Data Exchange (ETDEWEB)

Sellers, David; Friedman, Hannah; Haasl, Tudi; Bourassa, Norman; Piette, Mary Ann

2003-05-01

The ''Control System Design Guide'' (Design Guide) provides methods and recommendations for the control system design process and control point selection and installation. Control systems are often the most problematic system in a building. A good design process that takes into account maintenance, operation, and commissioning can lead to a smoothly operating and efficient building. To this end, the Design Guide provides a toolbox of templates for improving control system design and specification. HVAC designers are the primary audience for the Design Guide. The control design process it presents will help produce well-designed control systems that achieve efficient and robust operation. The spreadsheet examples for control valve schedules, damper schedules, and points lists can streamline the use of the control system design concepts set forth in the Design Guide by providing convenient starting points from which designers can build. Although each reader brings their own unique questions to the text, the Design Guide contains information that designers, commissioning providers, operators, and owners will find useful.

Indirect control of quantum systems via an accessor: pure coherent control without system excitation

International Nuclear Information System (INIS)

Fu, H C; Dong Hui; Sun, C P; Liu, X F

2009-01-01

A pure indirect control of quantum systems via a quantum accessor is investigated. In this control scheme, we do not apply any external classical excitation fields on the controlled system and we control a quantum system via a quantum accessor and classical control fields control the accessor only. Complete controllability is investigated for arbitrary finite-dimensional quantum systems and exemplified by two- and three-dimensional systems. The scheme exhibits some advantages; it uses less qubits in the accessor and does not depend on the energy-level structure of the controlled system

Intelligent control systems 1990

International Nuclear Information System (INIS)

Shoureshi, R.

1991-01-01

The field of artificial intelligence (Al) has generated many useful ideas and techniques that can be integrated into the design of control systems. It is believed and, for special cases, has been demonstrated, that integration of Al into control systems would provide the necessary tools for solving many of the complex problems that present control techniques and Al algorithms are unable to do, individually. However, this integration requires the development of basic understanding and new fundamentals to provide scientific bases for achievement of its potential. This book presents an overview of some of the latest research studies in the area of intelligent control systems. These papers present techniques for formulation of intelligent control, and development of the rule-based control systems. Papers present applications of control systems in nuclear power plants and HVAC systems

FFTF control system experience

International Nuclear Information System (INIS)

Warrick, R.P.

1981-01-01

The FFTF control systems provide control equipment for safe and efficient operation of the plant. For convenience, these systems will be divided into three parts for discussions: (1) Plant Protection System (PPS); (2) Plant Control System (PCS); and (3) General Observations. Performance of each of these systems is discussed

Entry-Control Systems Handbook

International Nuclear Information System (INIS)

1978-09-01

The function of an entry-control system in a total Physical Protection System is to allow the movement of authorized personnel and material through normal access routes, yet detect and delay unauthorized movement of personnel and material from uncontrolled areas. The ten chapters of this handbook cover: introduction, credentials, personnel identity verification systems, special nuclear materials monitors, metal detectors, explosives sensors, package search systems, criteria for selection of entry-control equipment, machine-aided manual entry-control systems, and automated entry-control systems. A system example and its cost are included as an appendix

Ventricular assist device elicits serum natural IgG that correlates with the development of primary graft dysfunction following heart transplantation.

Science.gov (United States)

See, Sarah B; Clerkin, Kevin J; Kennel, Peter J; Zhang, Feifan; Weber, Matthew P; Rogers, Kortney J; Chatterjee, Debanjana; Vasilescu, Elena R; Vlad, George; Naka, Yoshifumi; Restaino, Susan W; Farr, Maryjane A; Topkara, Veli K; Colombo, Paolo C; Mancini, Donna M; Schulze, P Christian; Levin, Bruce; Zorn, Emmanuel

2017-08-01

Pre-transplant sensitization is a limiting factor in solid-organ transplantation. In heart transplants, ventricular assist device (VAD) implantation has been associated with sensitization to human leukocyte antigens (HLA). The effect of VAD on non-HLA antibodies is unclear. We have previously shown that polyreactive natural antibodies (Nabs) contribute to pre-sensitization in kidney allograft recipients. Here we assessed generation of Nabs after VAD implantation in pre-transplant sera and examined their contribution to cardiac allograft outcome. IgM and IgG Nabs were tested in pre-transplant serum samples collected from 206 orthotopic heart transplant recipients, including 128 patients with VAD (VAD patients) and 78 patients without VAD (no-VAD patients). Nabs were assessed by testing serum reactivity to apoptotic cells by flow cytometry and to the generic oxidized epitope, malondialdehyde, by enzyme-linked immunosorbent assay. No difference was observed in serum levels of IgM Nabs between VAD and no-VAD patients. However, serum IgG Nabs levels were significantly increased in VAD compared with no-VAD patients. This increase was likely due to the presence of the VAD, as revealed by lower serum IgG Nabs levels before implantation. Elevated pre-transplant IgG Nabs level was associated with development of primary graft dysfunction (PGD). Our study demonstrates that VAD support elicits IgG Nabs reactive to apoptotic cells and oxidized epitopes. These findings further support broad and non-specific B-cell activation by VAD, resulting in IgG sensitization. Moreover, the association of serum IgG Nabs levels with development of PGD suggests a possible role for these antibodies in the inflammatory reaction accompanying this complication. Copyright © 2017 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Wisdom Appliance Control System

Science.gov (United States)

Hendrick; Jheng, Jyun-Teng; Tsai, Chen-Chai; Liou, Jia-Wei; Wang, Zhi-Hao; Jong, Gwo-Jia

2017-07-01

Intelligent appliances wisdom involves security, home care, convenient and energy saving, but the home automation system is still one of the core unit, and also using micro-processing electronics technology to centralized and control the home electrical products and systems, such as: lighting, television, fan, air conditioning, stereo, it composed of front-controller systems and back-controller panels, user using front-controller to control command, and then through the back-controller to powered the device.

Model predictive control for a thermostatic controlled system

DEFF Research Database (Denmark)

Shafiei, Seyed Ehsan; Rasmussen, Henrik; Stoustrup, Jakob

2013-01-01

This paper proposes a model predictive control scheme to provide temperature set-points to thermostatic controlled cooling units in refrigeration systems. The control problem is formulated as a convex programming problem to minimize the overall operating cost of the system. The foodstuff temperat......This paper proposes a model predictive control scheme to provide temperature set-points to thermostatic controlled cooling units in refrigeration systems. The control problem is formulated as a convex programming problem to minimize the overall operating cost of the system. The foodstuff...

System control and communication

International Nuclear Information System (INIS)

Bindner, H.; Oestergaard, J.

2005-01-01

Rapid and ongoing development in the energy sector has consequences for system control at all levels. In relation to system control and communication the control system is challenged in five important ways: 1) Expectations for security of supply, robustness and vulnerability are becoming more stringent, and the control system plays a big part in meeting these expectations. 2) Services are becoming increasingly based on markets that involve the transmission system operators (TSOs), generators and distribution companies. Timely, accurate and secure communication is essential to the smooth running of the markets. 3) Adding large amounts of renewable energy (RE) to the mix is a challenge for control systems because of the intermittent availability of many RE sources. 4) Increasing the number of active components in the system, such as small CHP plants, micro-CHP and intelligent loads, means that the system control will be much more complex. 5) In the future it is likely that power, heat, gas, transport and communication systems will be tighter coupled and interact much more. (au)

Development of ventricular assist devices in China: present status, opportunities and challenges.

Science.gov (United States)

Gu, Kaiyun; Chang, Yu; Gao, Bin; Wan, Feng; Loisance, Daniel; Zeng, Yi

2014-08-01

The growing number of heart failure patients and the scarcity of organ donors account for the huge need for the development of mechanical circulatory systems, including ventricular assist devices (VADs) and artificial hearts, in China. Several research programmes on blood pumps have been under way for the last three decades. However, unlike in other countries, the development of VADs has been extremely slow, and no system is currently approved and available for clinical application. There are many reasons for this situation. This article provides an overview of the present development of experimental and clinical research on VADs in China. In addition, the challenges for the clinical development of mechanical circulatory support in China are discussed. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Plug-and-Play Control – Modifying Control Systems Online

DEFF Research Database (Denmark)

Bendtsen, Jan Dimon; Trangbæk, K; Stoustrup, Jakob

2013-01-01

Often, when new sensor or actuator hardware be- comes available for use in a control system, it is desirable to retain the existing control system and apply the new control capabilities in a gradual fashion rather than decommissioning the entire existing system and replacing it with an altogether...... new control system. However, this requires that the existing controller remains in action, and the new control law component is added to the existing system. This paper formally introduces the concept of Plug-and-Play control and proposes two different methods of introducing new control components...

Heart rate control with adrenergic blockade: Clinical outcomes in cardiovascular medicine

Directory of Open Access Journals (Sweden)

David Feldman

2010-05-01

Full Text Available David Feldman1, Terry S Elton2, Doron M Menachemi3, Randy K Wexler41Heart Failure/Transplant and VAD Programs, Minneapolis Heart Institute, Minneapolis, Minnesota, USA; 2Division of Pharmacology, College of Pharmacology, The Ohio State University, Columbus, Ohio, USA; 3Heart Failure Services, Edith Wolfson Medical Center, The Heart Institute, Sakler School of Medicine, Tel-Aviv University, Holon, Israel; 4Department of Clinical Family Medicine, The Ohio State University, Columbus, Ohio, USAAbstract: The sympathetic nervous system is involved in regulating various cardiovascular parameters including heart rate (HR and HR variability. Aberrant sympathetic nervous system expression may result in elevated HR or decreased HR variability, and both are independent risk factors for development of cardiovascular disease, including heart failure, myocardial infarction, and hypertension. Epidemiologic studies have established that impaired HR control is linked to increased cardiovascular morbidity and mortality. One successful way of decreasing HR and cardiovascular mortality has been by utilizing β-blockers, because their ability to alter cell signaling at the receptor level has been shown to mitigate the pathogenic effects of sympathetic nervous system hyperactivation. Numerous clinical studies have demonstrated that β-blocker-mediated HR control improvements are associated with decreased mortality in postinfarct and heart failure patients. Although improved HR control benefits have yet to be established in hypertension, both traditional and vasodilating β-blockers exert positive HR control effects in this patient population. However, differences exist between traditional and vasodilating β-blockers; the latter reduce peripheral vascular resistance and exert neutral or positive effects on important metabolic parameters. Clinical evidence suggests that attainment of HR control is an important treatment objective for patients with cardiovascular

Networked control of microgrid system of systems

Science.gov (United States)

Mahmoud, Magdi S.; Rahman, Mohamed Saif Ur; AL-Sunni, Fouad M.

2016-08-01

The microgrid has made its mark in distributed generation and has attracted widespread research. However, microgrid is a complex system which needs to be viewed from an intelligent system of systems perspective. In this paper, a network control system of systems is designed for the islanded microgrid system consisting of three distributed generation units as three subsystems supplying a load. The controller stabilises the microgrid system in the presence of communication infractions such as packet dropouts and delays. Simulation results are included to elucidate the effectiveness of the proposed control strategy.

Clinical effectiveness and cost-effectiveness of second- and third-generation left ventricular assist devices as either bridge to transplant or alternative to transplant for adults eligible for heart transplantation: systematic review and cost-effectiveness model.

Science.gov (United States)

Sutcliffe, P; Connock, M; Pulikottil-Jacob, R; Kandala, N-B; Suri, G; Gurung, T; Grove, A; Shyangdan, D; Briscoe, S; Maheswaran, H; Clarke, A

2013-11-01

Advanced heart failure (HF) is a debilitating condition for which heart transplant (HT) offers the best treatment option. However, the supply of donor hearts is diminishing and demand greatly exceeds supply. Ventricular assist devices (VADs) are surgically implanted pumps used as an alternative to transplant (ATT) or as a bridge to transplant (BTT) while a patient awaits a donor heart. Surgery and VADs are costly. For the NHS to allocate and deliver such services in a cost-effective way the relative costs and benefits of these alternative treatments need to be estimated. To investigate for patients aged ≥ 16 years with advanced HF eligible for HT: (1) the clinical effectiveness and cost-effectiveness of second- and third-generation VADs used as BTT compared with medical management (MM); and (2) the clinical effectiveness and cost-effectiveness of second- and third-generation VADs used as an ATT in comparison with their use as BTT therapy. Searches for clinical effectiveness studies covered years from 2003 to March 2012 and included the following data bases: MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane Database of Systematic Reviews (CDSR), Database of Abstracts of Reviews of Effects (DARE), NHS Economic Evaluation Database (NHS EED), HTA databases [NHS Centre for Reviews and Dissemination (CRD)], Science Citation Index and Conference Proceedings (Web of Science), UK Clinical Research Network (UKCRN) Portfolio Database, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO and National Library of Medicine (NLM) Gateway, Cochrane Central Register of Controlled Trials (CENTRAL), Current Controlled Trials and ClinicalTrials.gov. Reference lists of relevant articles were checked, and VAD manufacturers' websites interrogated. For economic analyses we made use of individual patient data (IPD) held in the UK Blood and Transplant Database (BTDB). Systematic reviews of evidence on clinical effectiveness and cost

Controlling chaotic systems via nonlinear feedback control

International Nuclear Information System (INIS)

Park, Ju H.

2005-01-01

In this article, a new method to control chaotic systems is proposed. Using Lyapunov method, we design a nonlinear feedback controller to make the controlled system be stabilized. A numerical example is given to illuminate the design procedure and advantage of the result derived

Applied Control Systems Design

CERN Document Server

Mahmoud, Magdi S

2012-01-01

Applied Control System Design examines several methods for building up systems models based on real experimental data from typical industrial processes and incorporating system identification techniques. The text takes a comparative approach to the models derived in this way judging their suitability for use in different systems and under different operational circumstances. A broad spectrum of control methods including various forms of filtering, feedback and feedforward control is applied to the models and the guidelines derived from the closed-loop responses are then composed into a concrete self-tested recipe to serve as a check-list for industrial engineers or control designers. System identification and control design are given equal weight in model derivation and testing to reflect their equality of importance in the proper design and optimization of high-performance control systems. Readers’ assimilation of the material discussed is assisted by the provision of problems and examples. Most of these e...

Expert systems in process control systems

International Nuclear Information System (INIS)

Wittig, T.

1987-01-01

To illustrate where the fundamental difference between expert systems in classical diagnosis and in industrial control lie, the work of process control instrumentation is used as an example for the job of expert systems. Starting from the general process of problem-solving, two classes of expert systems can be defined accordingly. (orig.) [de

Modernization of turbine control system and reactor control system in Almaraz 1 and 2

International Nuclear Information System (INIS)

Pulido, C.; Diez, J.; Carrasco, J. A.; Lopez, L.

2005-01-01

The replacement of the Turbine Control System and Reactor Control System are part of the Almaraz modernization program for the Instrumentation and Control. For these upgrades Almaraz has selected the Ovation Platform that provides open architecture and easy expansion to other systems, these platforms is highly used in many nuclear and thermal plants around the world. One of the main objective for this project were to minimize the impact on the installation and operation of the plant, for that reason the project is implemented in two phases, Turbine Control upgrade and Reactor Control upgrade. Another important objective was to increase the reliability of the control system making them fully fault tolerant to single failures. The turbine Control System has been installed in Units 1 and 2 while the Reactor Control System will be installed in 2006 and 2007 outages. (Author)

Digital control system of advanced reactor

International Nuclear Information System (INIS)

Peng Huaqing; Zhang Rui; Liu Lixin

2001-01-01

This article produced the Digital Control System For Advanced Reactor made by NPIC. This system uses Siemens SIMATIC PCS 7 process control system and includes five control system: reactor power control system, pressurizer level control system, pressurizer pressure control system, steam generator water level control system and dump control system. This system uses three automatic station to realize the function of five control system. Because the safety requisition of reactor is very strict, the system is redundant. The system configuration uses CFC and SCL. the human-machine interface is configured by Wincc. Finally the system passed the test of simulation by using RETRAN 02 to simulate the control object. The research solved the key technology of digital control system of reactor and will be very helpful for the nationalization of digital reactor control system

Single-center experience of the bridge-to-bridge strategy using the Nipro paracorporeal ventricular assist device.

Science.gov (United States)

Yoshitake, Shuichi; Kinoshita, Osamu; Nawata, Kan; Hoshino, Yasuhiro; Itoda, Yoshifumi; Kimura, Mitsutoshi; Yamauchi, Haruo; Ono, Minoru

2018-06-25

Currently, we use the Nipro paracorporeal VAD (p-VAD) for initial short-term ventricular support, as a bridge to decision (BTD) or a bridge to candidacy (BTC) treatment, in Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) levels 1 and 2 patients. However, it is possible that compared to patients with primary implantable-VADs (P-iVAD), the bridge-to-bridge (BTB) patients are more likely to develop complications. This retrospective study used data from 24 consecutive BTB patients who were initially implanted with Nipro p-VAD as BTD or BTC treatments between April 2011 and March 2016, and subsequently underwent conversion to an i-VAD. The data from 72 patients who underwent a primary i-VAD (P-iVAD) procedure were used for comparison. Between the two groups, there was no significant difference in the incidence of infectious events (p = 0.72) or stroke (p = 0.44). Orthotropic heart transplantation was performed in 6 of the 24 patients in the BTB group and in 21 of the 72 patients in the P-iVAD group. The 1- and 2-year survival rates were 95.8% and 95.8% in the BTB group and 91% and 85.8% in the P-iVAD group; these values were not significantly different between groups (p = 0.91). Based on these results we conclude that BTB using Nipro p-VAD is a reasonable strategy for treating patients with severe decompensated end-stage heart failure.

Test results of HTTR control system

International Nuclear Information System (INIS)

Motegi, Toshihiro; Iigaki, Kazuhiko; Saito, Kenji; Sawahata, Hiroaki; Hirato, Yoji; Kondo, Makoto; Shibutani, Hideki; Ogawa, Satoru; Shinozaki, Masayuki; Mizushima, Toshihiko; Kawasaki, Kozo

2006-06-01

The plant control performance of the IHX helium flow rate control system, the PPWC helium flow rate control system, the secondary helium flow rate control system, the inlet temperature control system, the reactor power control system and the outlet temperature control system of the HTTR are obtained through function tests and power-up tests. As the test results, the control systems show stable control response under transient condition. Both of inlet temperature control system and reactor power control system shows stable operation from 30% to 100%, respectively. This report describes the outline of control systems and test results. (author)

Vad är den främst avgörande faktorn vid privatkundens val av marginalbank? : en studie om hur demografiska skillnader påverkar privatkunders val av marginalbank samt se hur deras val kan användas vid segmentering

OpenAIRE

Lindh, Jenni; Persson, Frida

2012-01-01

Syfte: Syftet med detta examensarbete är att förklara vad som är den främst avgörande faktorn vid privatkundens val av marginalbank, genom att jämföra med demografiska variabler samt hur deras val kan användas vid segmentering. Dessutom vill vi titta på vilka typer av banker privatkunder har. Metod: För att nå fram till resultat för analysen har ett positivistiskt angreppssätt och en deduktiv ansats använts. Det empiriska materialet är baserat på en enkätundersökning gjord på personer i Hässl...

The ILC control system

International Nuclear Information System (INIS)

Carwardine, J.; Saunders, C.; Arnold, N.; Lenkszus, F.; Rehlich, K.; Simrock, S.; Banerjee, b.; Chase, B.; Gottschalk, E.; Joireman, P.; Kasley, P.; Lackey, S.; McBride, P.; Pavlicek, V.; Patrick, J.; Votava, M.; Wolbers, S.; Furukawa, K.; Michizono, S.; Larson, R.S.; Downing, R.

2007-01-01

Since the last ICALEPCS, a small multi-region team has developed a reference design model for a control system for the International Linear Collider as part of the ILC Global Design Effort. The scale and performance parameters of the ILC accelerator require new thinking in regards to control system design. Technical challenges include the large number of accelerator systems to be controlled, the large scale of the accelerator facility, the high degree of automation needed during accelerator operations, and control system equipment requiring 'Five Nines' availability. The R and D path for high availability touches the control system hardware, software, and overall architecture, and extends beyond traditional interfaces into the technical systems. Software considerations for HA include fault detection through exhaustive out-of-band monitoring and automatic state migration to redundant systems, while the telecom industry's emerging ATCA standard - conceived, specified, and designed for High Availability - is being evaluated for suitability for ILC front-end electronics.

Control system integration

CERN Document Server

Shea, T J

2008-01-01

This lecture begins with a definition of an accelerator control system, and then reviews the control system architectures that have been deployed at the larger accelerator facilities. This discussion naturally leads to identification of the major subsystems and their interfaces. We shall explore general strategies for integrating intelligent devices and signal processing subsystems based on gate arrays and programmable DSPs. The following topics will also be covered: physical packaging; timing and synchronization; local and global communication technologies; interfacing to machine protection systems; remote debugging; configuration management and source code control; and integration of commercial software tools. Several practical realizations will be presented.

ALFA Detector Control System

CERN Document Server

Oleiro Seabra, Luis Filipe; The ATLAS collaboration

2015-01-01

ALFA (Absolute Luminosity For ATLAS) is one of the sub-detectors of ATLAS (A Toroidal LHC Apparatus). The ALFA system is composed by four stations installed in the LHC tunnel 240 m away from the ATLAS interaction point. Each station has a vacuum and ventilation system, movement control and all the required electronics for signal processing. The Detector Control System (DCS) provides control and monitoring of several components and ensures the safe operation of the detector contributing to good Data Quality. This paper describes the ALFA DCS system including a detector overview, operation aspects and hardware control through a SCADA system, WinCC OA.

ALFA Detector Control System

CERN Document Server

Oleiro Seabra, Luis Filipe; The ATLAS collaboration

2015-01-01

ALFA (Absolute Luminosity For ATLAS) is one of the sub-detectors of ATLAS/LHC. The ALFA system is composed by two stations installed in the LHC tunnel 240 m away from each side of the ATLAS interaction point. Each station has a vacuum and ventilation system, movement control and all the required electronic for signal processing. The Detector Control System (DCS) provides control and monitoring of several components and ensures the safe operation of the detector contributing to good Data Quality. This paper describes the ALFA DCS system including a detector overview, operation aspects and hardware control through a SCADA system, WinCC OA.

Vitamin D status and vascular dementia due to cerebral small vessel disease in the elderly Asian Indian population.

Science.gov (United States)

Prabhakar, Puttachandra; Chandra, Sadanandavalli Retnaswami; Supriya, Manjunath; Issac, Thomas Gregor; Prasad, Chandrajit; Christopher, Rita

2015-12-15

Vitamin D plays vital roles in human health and recent studies have shown its beneficial effect on brain functioning. The present study was designed to evaluate the association of vitamin D with vascular dementia (VaD) due to cerebral small vessel disease (SVD) in Asian Indian population. 140 VaD patients aged ≥ 60 years with neuroimaging evidence of SVD, and 132 age and gender-matched controls, were investigated. Vitamin D status was estimated by measuring serum 25-hydroxy vitamin D. Logistic regression model revealed that deficient levels of vitamin D (vitamin D deficiency and insufficiency (12-20 ng/ml), the odds were increased to 31.6-fold and 14.4-fold, respectively. However, in hypertensives with vitamin D sufficiency (>20 ng/ml), the odds of VaD were increased by 3.8-fold only. Pearson correlation showed that serum vitamin D was inversely associated with systolic and diastolic blood pressure (r=-0.401 and -0.411, pvitamin D-deficient subjects. Since the combined presence of hypertension and vitamin D deficiency increases the probability of developing VaD, screening for vitamin D status in addition to regular monitoring of blood pressure, could reduce the risk of VaD associated with cerebral SVD in the elderly Asian Indian subjects. Copyright © 2015 Elsevier B.V. All rights reserved.

The CEBAF control system

International Nuclear Information System (INIS)

Watson, W.A. III.

1995-01-01

CEBAF has recently upgraded its accelerator control system to use EPICS, a control system toolkit being developed by a collaboration among laboratories in the US and Europe. The migration to EPICS has taken place during a year of intense commissioning activity, with new and old control systems operating concurrently. Existing CAMAC hardware was preserved by adding a CAMAC serial highway link to VME; newer hardware developments are now primarily in VME. Software is distributed among three tiers of computers: first, workstations and X terminals for operator interfaces and high level applications; second, VME single board computers for distributed access to hardware and for local control processing; third, embedded processors where needed for faster closed loop operation. This system has demonstrated the ability to scale EPICS to controlling thousands of devices, including hundreds of embedded processors, with control distributed among dozens of VME processors executing more than 125,000 EPICS database records. To deal with the large size of the control system, CEBAF has integrated an object oriented database, providing data management capabilities for both low level I/O and high level machine modeling. A new callable interface which is control system independent permits access to live EPICS data, data in other Unix processes, and data contained in the object oriented database

Output controllability of nonlinear systems with bounded control

International Nuclear Information System (INIS)

Garcia, Rafael; D'Attellis, Carlos

1990-01-01

The control problem treated in this paper is the output controllability of a nonlinear system in the form: x = f(x) + g(x)u(t); y = h(x), using bounded controls. The approach to the problem consists of a modification in the system using dynamic feedback in such a way that the input/output behaviour of the closed loop matches the input/output behaviour of a completely output-controllable system with bounded controls. Sufficient conditions are also put forward on the system so that a compact set in the output space may be reached in finite time using uniformally bounded controls, and a result on output regulation in finite time with asymptotic state stabilization is obtained. (Author)

Comparison of Alzheimer's disease with vascular dementia and non-dementia using specific voxel-based Z score maps

International Nuclear Information System (INIS)

Ishii, Shirou; Shishido, Fumio; Miyajima, Masayuki; Sakuma, Koutarou; Shigihara, Takeshi; Tameta, Tadanobu; Miyazaki, Makoto; Kuroda, Hiroshi

2009-01-01

We investigated the ability to discriminate between Alzheimer's disease (AD) and vascular dementia (VaD), and between AD and non-dementia using the program ''easy Z score imaging system'' (eZIS) developed by Matsuda et al., for the diagnosis of very early AD. Of 201 patients, we investigated 12 patients with AD, 10 with VaD, and 9 with non-dementia, who underwent brain perfusion single-photon emission computed tomography by technetium-99m ethyl cysteinate dimer ( 99m Tc-ECD) between February 2005 and September 2006. The sensitivity and specificity of the indicators of specific volume of interest (VOI) analysis, namely, severity, extent, and ratio were evaluated for the distinction of AD from VaD and non-dementia. There was a significant difference in all the criteria for severity, extent, and ratio between AD and non-dementia cases and in the ratio between AD and VaD. Between AD and non-dementia, the sensitivity and specificity of severity were 100% and 45%, respectively, using the cutoff value of 1.19. When using the cutoff value of 14.2 for extent, the sensitivity and specificity were both 100%. Using the cutoff value of 2.22 for ratio, the sensitivity of 42% and specificity of 100% were demonstrated. When comparing AD with VaD, using the cutoff value of 2.22 for ratio, the sensitivity and specificity were 42% and 100%, respectively. Using the cutoff value of 1.5 for ratio, the sensitivity and specificity between AD and VaD were 92% and 80%, respectively, thereby showing the best results. The specific VOI analysis program of AD using specific voxel-based Z score maps is not influenced by interobserver differences among radiologists and is useful to discriminate AD from VaD and non-dementia. However, the setting of the cutoff value at each institution and comparison with original and eZIS images are suggested to distinguish better AD from VaD. (author)

SPring-8 beamline control system.

Science.gov (United States)

Ohata, T; Konishi, H; Kimura, H; Furukawa, Y; Tamasaku, K; Nakatani, T; Tanabe, T; Matsumoto, N; Ishii, M; Ishikawa, T

1998-05-01

The SPring-8 beamline control system is now taking part in the control of the insertion device (ID), front end, beam transportation channel and all interlock systems of the beamline: it will supply a highly standardized environment of apparatus control for collaborative researchers. In particular, ID operation is very important in a third-generation synchrotron light source facility. It is also very important to consider the security system because the ID is part of the storage ring and is therefore governed by the synchrotron ring control system. The progress of computer networking systems and the technology of security control require the development of a highly flexible control system. An interlock system that is independent of the control system has increased the reliability. For the beamline control system the so-called standard model concept has been adopted. VME-bus (VME) is used as the front-end control system and a UNIX workstation as the operator console. CPU boards of the VME-bus are RISC processor-based board computers operated by a LynxOS-based HP-RT real-time operating system. The workstation and the VME are linked to each other by a network, and form the distributed system. The HP 9000/700 series with HP-UX and the HP 9000/743rt series with HP-RT are used. All the controllable apparatus may be operated from any workstation.

Study of diffusion tensor imaging in subcortical ischemic vascular cognitive impairment

Directory of Open Access Journals (Sweden)

Hui-ying GUO

2014-04-01

Full Text Available Objective Using diffusion tensor imaging (DTI to explore the microstructure changes of white matter in subcortical ischemic vascular cognitive impairment (SIVCI and its correlation with cognitive function.  Methods Forty-nine patients with subcortical ischemic cerebrovascular diseases were collected. By using Clinical Dementia Rating Scale (CDR, they were classified into 10 cases of vascular dementia (VaD group, 20 cases of vascular cognitive impairment-no dementia (VCIND group and 19 cases of normal cognitive function (control group. Conventional MRI and DTI were performed in all cases. Based on the DTI data, voxel-based analysis was used to assess the whole brain region. Correlation analysis was applied to illustrate the relationship between DTI parameters and cognitive scale in VaD patients.  Results Compared with the control group, fractional anisotropy (FA values of patients in VaD group decreased in medial prefrontal cortex, anterior cingulate cortex, corpus callosum stem, bilateral parietal lobes, right temporal lobe and bilateral orbitofrontal lobes (P = 0.000, for all, and FA values of patients in VCIND group decreased in right inferior frontal gyrus, right hippocampus and bilateral precuneus (P = 0.000, for all. Compared with VCIND group, FA values of patients in VaD group decreased in medial prefrontal cortex, anterior cingulate, corpus callosum, bilateral parietal lobes and right temporal lobe (P = 0.000, for all. Compared with the control group, mean diffusivity (MD values in VaD group increased in medial prefrontal cortex, corpus callosum, bilateral parietal lobes, bilateral temporal lobes and anterior cingulate (P = 0.000, for all, while in VCIND group increased in bilateral precuneus and right hippocampus (P = 0.000, for all. Compared with VCIND group, MD values in VaD group increased in right medial prefrontal cortex, anterior cingulate cortex, corpus callosum stem, bilateral parietal lobes and bilateral temporal lobes (P = 0

The APS control system network

International Nuclear Information System (INIS)

Sidorowicz, K.V.; McDowell, W.P.

1995-01-01

The APS accelerator control system is a distributed system consisting of operator interfaces, a network, and computer-controlled interfaces to hardware. This implementation of a control system has come to be called the open-quotes Standard Model.close quotes The operator interface is a UNDC-based workstation with an X-windows graphical user interface. The workstation may be located at any point on the facility network and maintain full functionality. The function of the network is to provide a generalized communication path between the host computers, operator workstations, input/output crates, and other hardware that comprise the control system. The crate or input/output controller (IOC) provides direct control and input/output interfaces for each accelerator subsystem. The network is an integral part of all modem control systems and network performance will determine many characteristics of a control system. This paper will describe the overall APS network and examine the APS control system network in detail. Metrics are provided on the performance of the system under various conditions

Personal exposure control system

International Nuclear Information System (INIS)

Tanabe, Ken-ichi; Akashi, Michio

1994-01-01

Nuclear power stations are under strict radiation control. Exposure control for nuclear workers is the most important operation, and so carefully thought out measures are taken. This paper introduces Fuji Electric's personal exposure control system that meets strict exposure control and rationalizes control operations. The system has a merit that it can provide required information in an optimum form using the interconnection of a super minicomputer and exposure control facilities and realizes sophisticated exposure control operations. (author)

Hybrid spacecraft attitude control system

Directory of Open Access Journals (Sweden)

Renuganth Varatharajoo

2016-02-01

Full Text Available The hybrid subsystem design could be an attractive approach for futurespacecraft to cope with their demands. The idea of combining theconventional Attitude Control System and the Electrical Power System ispresented in this article. The Combined Energy and Attitude ControlSystem (CEACS consisting of a double counter rotating flywheel assemblyis investigated for small satellites in this article. Another hybrid systemincorporating the conventional Attitude Control System into the ThermalControl System forming the Combined Attitude and Thermal ControlSystem (CATCS consisting of a "fluid wheel" and permanent magnets isalso investigated for small satellites herein. The governing equationsdescribing both these novel hybrid subsystems are presented and theironboard architectures are numerically tested. Both the investigated novelhybrid spacecraft subsystems comply with the reference missionrequirements.The hybrid subsystem design could be an attractive approach for futurespacecraft to cope with their demands. The idea of combining theconventional Attitude Control System and the Electrical Power System ispresented in this article. The Combined Energy and Attitude ControlSystem (CEACS consisting of a double counter rotating flywheel assemblyis investigated for small satellites in this article. Another hybrid systemincorporating the conventional Attitude Control System into the ThermalControl System forming the Combined Attitude and Thermal ControlSystem (CATCS consisting of a "fluid wheel" and permanent magnets isalso investigated for small satellites herein. The governing equationsdescribing both these novel hybrid subsystems are presented and theironboard architectures are numerically tested. Both the investigated novelhybrid spacecraft subsystems comply with the reference missionrequirements.

Load Control System Reliability

Energy Technology Data Exchange (ETDEWEB)

Trudnowski, Daniel [Montana Tech of the Univ. of Montana, Butte, MT (United States)

2015-04-03

This report summarizes the results of the Load Control System Reliability project (DOE Award DE-FC26-06NT42750). The original grant was awarded to Montana Tech April 2006. Follow-on DOE awards and expansions to the project scope occurred August 2007, January 2009, April 2011, and April 2013. In addition to the DOE monies, the project also consisted of matching funds from the states of Montana and Wyoming. Project participants included Montana Tech; the University of Wyoming; Montana State University; NorthWestern Energy, Inc., and MSE. Research focused on two areas: real-time power-system load control methodologies; and, power-system measurement-based stability-assessment operation and control tools. The majority of effort was focused on area 2. Results from the research includes: development of fundamental power-system dynamic concepts, control schemes, and signal-processing algorithms; many papers (including two prize papers) in leading journals and conferences and leadership of IEEE activities; one patent; participation in major actual-system testing in the western North American power system; prototype power-system operation and control software installed and tested at three major North American control centers; and, the incubation of a new commercial-grade operation and control software tool. Work under this grant certainly supported the DOE-OE goals in the area of “Real Time Grid Reliability Management.”

Virtualization in control system environment

International Nuclear Information System (INIS)

Shen, L.R.; Liu, D.K.; Wan, T.M.

2012-01-01

In large scale distributed control system, there are lots of common service composed an environment for the entire control system, such as the server system for the common software base library, application server, archive server and so on. This paper gives a description of a virtualization realization for control system environment including the virtualization for server, storage, network system and application for the control system. With a virtualization instance of the EPICS based control system environment that was built by the VMware vSphere v4, we tested the whole functionality of this virtualization environment in the SSRF control system, including the common server of the NFS, NIS, NTP, Boot and EPICS base and extension library tools, we also have applied virtualization to application servers such as the Archive, Alarm, EPICS gateway and all of the network based IOC. Specially, we test the high availability and VMotion for EPICS asynchronous IOC successful under the different VLAN configuration of the current SSRF control system network. (authors)

Impact of ventricular assist device placement on longitudinal renal function in children with end-stage heart failure.

Science.gov (United States)

May, Lindsay J; Montez-Rath, Maria E; Yeh, Justin; Axelrod, David M; Chen, Sharon; Maeda, Katsuhide; Almond, Christopher S D; Rosenthal, David N; Hollander, Seth A; Sutherland, Scott M

2016-04-01

Although ventricular assist devices (VADs) restore hemodynamics in those with heart failure, reversibility of end-organ dysfunction with VAD support is not well characterized. Renal function often improves in adults after VAD placement, but this has not been comprehensively explored in children. Sixty-three children on VAD support were studied. Acute kidney injury (AKI) was defined by Kidney Disease: Improving Global Outcomes criteria. Estimated glomerular filtration rate (eGFR) was determined by the Schwartz method. Generalized linear mixed-effects models compared the pre-VAD and post-VAD eGFR for the cohort and sub-groups with and without pre-VAD renal dysfunction (pre-VAD eGFR renal dysfunction. AKI affected 60.3% (38 of 63), with similar rates in those with and without pre-existing renal dysfunction. Within the cohort, the nadir eGFR occurred 1 day post-operatively (62.9 ml/min/1.73 m(2); IQR, 51.2-88.9 ml/min/1.73 m(2); p renal dysfunction experienced the greatest improvement in the eGFR (β = 0.0051 vs β = 0.0013, p Renal dysfunction is prevalent in children with heart failure undergoing VAD placement. Although peri-operative AKI is common, renal function improves substantially in the first post-operative week and for months thereafter. This is particularly pronounced in those with pre-VAD renal impairment, suggesting that VADs may facilitate recovery and maintenance of kidney function in children with advanced heart failure. Copyright © 2016 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Qualitative aspects of learning, recall, and recognition in dementia

Directory of Open Access Journals (Sweden)

Ranjith Neelima

2010-01-01

Full Text Available Objective: To determine whether learning and serial position effect (SPE differs qualitatively and quantitatively among different types of dementia and between dementia patients and controls; we also wished to find out whether interference affects it. Materials and Methods: We administered the Malayalam version of the Rey Auditory Verbal Learning Test (RAVLT to 30 cognitively unimpaired controls and 80 dementia patients [30 with Alzheimer′s disease (AD, 30 with vascular dementia (VaD, and 20 with frontotemporal dementia (FTD] with mild severity on the Clinical Dementia Rating Scale. Results: All groups were comparable on education and age, except the FTD group, who were younger. Qualitatively, the learning pattern and SPE (with primacy and recency being superior to intermediate was retained in the AD, VaD, and control groups. On SPE in free recall, recency was superior to intermediate in the FTD group (P < 0.01 using Bonferroni correction. On recognition, the AD and VaD groups had more misses (P < 0.01, while the FTD group had more false positives (P < 0.01. Conclusion: Quantitative learning is affected by dementia. The pattern of qualitative learning remains unaltered in dementia in the early stages.

Single axis controlled hybrid magnetic bearing for left ventricular assist device: hybrid core and closed magnetic circuit.

Science.gov (United States)

da Silva, Isaias; Horikawa, Oswaldo; Cardoso, Jose R; Camargo, Fernando A; Andrade, Aron J P; Bock, Eduardo G P

2011-05-01

In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in which the active control is executed in only one degree of freedom, in the axial direction of the rotor. Remaining degrees of freedom, excepting the rotation, are restricted only by the attraction force between pairs of permanent magnets. This study is part of a joint project in development by IDPC and Escola Politecnica of São Paulo University, Brazil. This article shows advances in that project, presenting two promising solutions for magnetic bearings. One solution uses hybrid cores as electromagnetic actuators, that is, cores that combine iron and permanent magnets. The other solution uses actuators, also of hybrid type, but with the magnetic circuit closed by an iron core. After preliminary analysis, a pump prototype has been developed for each solution and has been tested. For each prototype, a brushless DC motor has been developed as the rotor driver. Each solution was evaluated by in vitro experiments and guidelines are extracted for future improvements. Tests have shown good results and demonstrated that one solution is not isolated from the other. One complements the other for the development of a single-axis-controlled, hybrid-type magnetic bearing for a mixed-flow type VAD. © 2011, Copyright the Authors. Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

ISTTOK control system upgrade

Energy Technology Data Exchange (ETDEWEB)

Carvalho, Ivo S., E-mail: ivoc@ipfn.ist.utl.pt; Duarte, Paulo; Fernandes, Horácio; Valcárcel, Daniel F.; Carvalho, Pedro J.; Silva, Carlos; Duarte, André S.; Neto, André; Sousa, Jorge; Batista, António J.N.; Carvalho, Bernardo B.

2013-10-15

Highlights: •ISTTOK fast controller. •All real-time diagnostic and actuators were integrated in the control platform. •100 μs control cycle under the MARTe framework. •The ISTTOK control system upgrade provides reliable operation with an improved operational space. -- Abstract: The ISTTOK tokamak (Ip = 4 kA, BT = 0.5 T, R = 0.46 m, a = 0.085 m) is one of the few tokamaks with regular alternate plasma current (AC) discharges scientific programme. In order to improve the discharge stability and to increase the number of AC discharge cycles a novel control system was developed. The controller acquires data from 50 analog-to-digital converter (ADC) channels of real-time diagnostics and measurements: tomography, Mirnov coils, interferometer, electric probes, sine and cosine probes, bolometer, current delivered by the power supplies, loop voltage and plasma current. The system has a control cycle of 100 μs during which it reads all the diagnostics connected to the advanced telecommunications computing architecture (ATCA) digitizers and sends the control reference to ISTTOK actuators. The controller algorithms are executed on an Intel{sup ®} Q8200 chip with 4 cores running at 2.33 GHz and connected to the I/O interfaces through an ATCA based environment. The real-time control system was programmed in C++ on top of the Multi-threaded Application Real-Time executor (MARTe). To extend the duration of the AC discharges and the plasma stability a new magnetising field power supply was commissioned and the horizontal and vertical field power supplies were also upgraded. The new system also features a user-friendly interface based on HyperText Markup Language (HTML) and Javascript to configure the controller parameters. This paper presents the ISTTOK control system and the consequent update of real-time diagnostics and actuators.

ISTTOK control system upgrade

International Nuclear Information System (INIS)

Carvalho, Ivo S.; Duarte, Paulo; Fernandes, Horácio; Valcárcel, Daniel F.; Carvalho, Pedro J.; Silva, Carlos; Duarte, André S.; Neto, André; Sousa, Jorge; Batista, António J.N.; Carvalho, Bernardo B.

2013-01-01

Highlights: •ISTTOK fast controller. •All real-time diagnostic and actuators were integrated in the control platform. •100 μs control cycle under the MARTe framework. •The ISTTOK control system upgrade provides reliable operation with an improved operational space. -- Abstract: The ISTTOK tokamak (Ip = 4 kA, BT = 0.5 T, R = 0.46 m, a = 0.085 m) is one of the few tokamaks with regular alternate plasma current (AC) discharges scientific programme. In order to improve the discharge stability and to increase the number of AC discharge cycles a novel control system was developed. The controller acquires data from 50 analog-to-digital converter (ADC) channels of real-time diagnostics and measurements: tomography, Mirnov coils, interferometer, electric probes, sine and cosine probes, bolometer, current delivered by the power supplies, loop voltage and plasma current. The system has a control cycle of 100 μs during which it reads all the diagnostics connected to the advanced telecommunications computing architecture (ATCA) digitizers and sends the control reference to ISTTOK actuators. The controller algorithms are executed on an Intel ® Q8200 chip with 4 cores running at 2.33 GHz and connected to the I/O interfaces through an ATCA based environment. The real-time control system was programmed in C++ on top of the Multi-threaded Application Real-Time executor (MARTe). To extend the duration of the AC discharges and the plasma stability a new magnetising field power supply was commissioned and the horizontal and vertical field power supplies were also upgraded. The new system also features a user-friendly interface based on HyperText Markup Language (HTML) and Javascript to configure the controller parameters. This paper presents the ISTTOK control system and the consequent update of real-time diagnostics and actuators

Robust lyapunov controller for uncertain systems

KAUST Repository

Laleg-Kirati, Taous-Meriem

2017-02-23

Various examples of systems and methods are provided for Lyapunov control for uncertain systems. In one example, a system includes a process plant and a robust Lyapunov controller configured to control an input of the process plant. The robust Lyapunov controller includes an inner closed loop Lyapunov controller and an outer closed loop error stabilizer. In another example, a method includes monitoring a system output of a process plant; generating an estimated system control input based upon a defined output reference; generating a system control input using the estimated system control input and a compensation term; and adjusting the process plant based upon the system control input to force the system output to track the defined output reference. An inner closed loop Lyapunov controller can generate the estimated system control input and an outer closed loop error stabilizer can generate the system control input.

Discovery of Acupoints and Combinations with Potential to Treat Vascular Dementia: A Data Mining Analysis

Directory of Open Access Journals (Sweden)

Shuwei Feng

2015-01-01

Full Text Available The prevalence of vascular dementia (VaD is high among the elderly. Acupuncture, a popular therapeutic method in China, can improve memory, orientation, calculation, and self-managing ability in VaD patients. However, in clinical acupuncture and acupuncture research, the selection of acupoints to treat VaD remains challenging. This study aimed to discover acupoints and acupoint combinations with potential for VaD based on data mining. After database searching and screening for articles on clinical trials evaluating the effects of acupuncture on VaD, 238 acupuncture prescriptions were included for further analysis. Baihui (GV 20, Sishencong (EX-HN 1, Fengchi (GB 20, Shuigou (GV 26, and Shenting (GV 24 appeared most frequently in the modern literature and are potential acupoints for VaD. Combinations between Baihui (GV 20, Sishencong (EX-HN 1, Fengchi (GB 20, Shenting (GV 24, Shuigou (GV 26, and Zusanli (ST 36 were most frequent and represent potential combinations for VaD treatment. These results provide a reference for the selection and combination of acupoints to treat VaD in clinical acupuncture and acupuncture research.

Vad behöver eleverna undervisning i för att utveckla sitt skrivande? Förväntningsnormer och didaktiska beslut i svensklärares bedömningssamtal

Directory of Open Access Journals (Sweden)

Per Blomqvist

2016-04-01

Full Text Available I studien samtalar tre lärargrupper om elevers skrivande och skrivundervisning i ämnet svenska på gymnasiet. Det teoretiska perspektiv som läggs på dessa samtal är didaktiskt och inriktas på hur lärare formulerar och använder bedömningsinformation om elevers skrivande för beslut om skrivundervisningens innehåll. Resultatet visar att lärares bedömningar av elevers skrivande behandlar fler och delvis andra aspekter av skrivförmåga än vad deras didaktiska beslut sedan omfattar. De kvalitetsuppfattningar och förväntningsnormer som lärarna uttrycker i sina bedömningar av elevers skrivande inriktas huvudsakligen på texters kommunikativa kvaliteter, den stilistiska utformningen och textuppbyggnaden, följt av ämnesinnehåll och källanvändning. De didaktiska beslut som fattas utifrån bedömningen av elevers texter inriktas däremot i stort sett enbart på att eleverna behöver skrivundervisning i att disponera text och att använda källor. Detta gör att överensstämmelsen är låg mellan lärarnas beslut om skrivundervisningens inriktning och deras förväntningar på vad eleverna ska kunna. De didaktiska besluten omfattar i begränsad utsträckning den bedömningsinformation som lärarna själva har formulerat.Nyckelord: Skrivbedömning, kvalitetsuppfattningar, förväntningsnormer, didaktiska beslut, formativ bedömning, svenskämnets didaktik, svenska på gymnasietAbstractThis article presents an analysis of teacher group discussions about students’ writing in the subject of Swedish in upper secondary school. The study adopts a pedagogical perspective on these discussions and focuses on examining teachers’ expressed assessment criteria and relating them to their pedagogical decision-making. The results reveal that the teachers’ assessments of students’ writing focus on much more, and partly other, criteria than their pedagogical decisions. The quality standards that teachers express in the discussions about

D0 Cryo System Control System Autodialer

Energy Technology Data Exchange (ETDEWEB)

Urbin, J.; /Fermilab

1990-04-17

The DO cryogenic system is controlled by a TI565-PLC based control system. This allows the system to be unmanned when in steady state operation. System experts will need to be contacted when system parameters exceed normal operating points and reach alarm setpoints. The labwide FIRUS system provides one alarm monitor and communication link. An autodialer provides a second and more flexible alarm monitor and communication link. The autodialer monitors contact points in the control system and after receiving indication of an alarm accesses a list of experts which it calls until it receives an acknowledgement. There are several manufacturers and distributors of autodialer systems. This EN explains the search process the DO cryo group used to fmd an autodialer system that fit the cryo system's needs and includes information and specs for the unit we chose.

System-Awareness for Agent-based Power System Control

DEFF Research Database (Denmark)

Heussen, Kai; Saleem, Arshad; Lind, Morten

2010-01-01

transition. This paper presents a concept for the representation and organization of control- and resource-allocation, enabling computational reasoning and system awareness. The principles are discussed with respect to a recently proposed Subgrid operation concept.......Operational intelligence in electric power systems is focused in a small number of control rooms that coordinate their actions. A clear division of responsibility and a command hierarchy organize system operation. With multi-agent based control systems, this control paradigm may be shifted...... to a more decentralized openaccess collaboration control paradigm. This shift cannot happen at once, but must fit also with current operation principles. In order to establish a scalable and transparent system control architecture, organizing principles have to be identified that allow for a smooth...

Component Control System for a Vehicle

Science.gov (United States)

Fraser-Chanpong, Nathan (Inventor); Spain, Ivan (Inventor); Dawson, Andrew D. (Inventor); Bluethmann, William J. (Inventor); Lee, Chunhao J. (Inventor); Vitale, Robert L. (Inventor); Guo, Raymond (Inventor); Waligora, Thomas M. (Inventor); Akinyode, Akinjide Akinniyi (Inventor); Reed, Ryan M. (Inventor)

2016-01-01

A vehicle includes a chassis, a modular component, and a central operating system. The modular component is supported by the chassis. The central operating system includes a component control system, a primary master controller, and a secondary master controller. The component control system is configured for controlling the modular component. The primary and secondary master controllers are in operative communication with the component control system. The primary and secondary master controllers are configured to simultaneously transmit commands to the component control system. The component control system is configured to accept commands from the secondary master controller only when a fault occurs in the primary master controller.

ISABELLE half-cell control system

International Nuclear Information System (INIS)

Buxton, W.; Frankel, R.; Humphrey, J.W.

1977-01-01

The primary function of the ISABELLE half-cell control system is to monitor and control the magnet power supplies of the half-cell. In addition, the control system must be flexible enough that it can be expanded to become involved in additional areas such as vacuum and magnetic measurements. A control system based upon AGS control standards, but modified into a development tool for research and electrical engineering support was constructed. Special attention was given to the inherent differences between controlling an ISABELLE and a conventional fast cycling accelerator. The use of FORTRAN and BASIC networks, and microprocessors is reviewed insofar as they pertain to this system. Some general opinions on model control systems, based upon experience, are presented

Ground Control System Description Document

International Nuclear Information System (INIS)

Eric Loros

2001-01-01

The Ground Control System contributes to the safe construction and operation of the subsurface facility, including accesses and waste emplacement drifts, by maintaining the configuration and stability of the openings during construction, development, emplacement, and caretaker modes for the duration of preclosure repository life. The Ground Control System consists of ground support structures installed within the subsurface excavated openings, any reinforcement made to the rock surrounding the opening, and inverts if designed as an integral part of the system. The Ground Control System maintains stability for the range of geologic conditions expected at the repository and for all expected loading conditions, including in situ rock, construction, operation, thermal, and seismic loads. The system maintains the size and geometry of operating envelopes for all openings, including alcoves, accesses, and emplacement drifts. The system provides for the installation and operation of sensors and equipment for any required inspection and monitoring. In addition, the Ground Control System provides protection against rockfall for all subsurface personnel, equipment, and the engineered barrier system, including the waste package during the preclosure period. The Ground Control System uses materials that are sufficiently maintainable and that retain the necessary engineering properties for the anticipated conditions of the preclosure service life. These materials are also compatible with postclosure waste isolation performance requirements of the repository. The Ground Control System interfaces with the Subsurface Facility System for operating envelopes, drift orientation, and excavated opening dimensions, Emplacement Drift System for material compatibility, Monitored Geologic Repository Operations Monitoring and Control System for ground control instrument readings, Waste Emplacement/Retrieval System to support waste emplacement operations, and the Subsurface Excavation System

Generic device controller for accelerator control systems

International Nuclear Information System (INIS)

Mariotti, R.; Buxton, W.; Frankel, R.; Hoff, L.

1987-01-01

A new distributed intelligence control system has become operational at the AGS for transport, injection, and acceleration of heavy ions. A brief description of the functionality of the physical devices making up the system is given. An attempt has been made to integrate the devices for accelerator specific interfacing into a standard microprocessor system, namely, the Universal Device Controller (UDC). The main goals for such a generic device controller are to provide: local computing power; flexibility to configure; and real time event handling. The UDC assemblies and software are described

Magnetic suspension of the rotor of a ventricular assist device of mixed flow type.

Science.gov (United States)

Horikawa, Oswaldo; de Andrade, Aron José Pazin; da Silva, Isaías; Bock, Eduardo Guy Perpetuo

2008-04-01

This work presents results of preliminary studies concerning application of magnetic bearing in a ventricular assist device (VAD) being developed by Dante Pazzanese Institute of Cardiology-IDPC (São Paulo, Brazil). The VAD-IDPC has a novel architecture that distinguishes from other known VADs. In this, the rotor has a conical geometry with spiral impellers, showing characteristics that are intermediate between a centrifugal VAD and an axial VAD. The effectiveness of this new type of blood pumping principle was showed by tests and by using it in heart surgery for external blood circulation. However, the developed VAD uses a combination of ball bearings and mechanical seals, limiting the life for some 10 h, making impossible its long-term use or its use as an implantable VAD. As a part of development of an implantable VAD, this work aims at the replacement of ball bearings by a magnetic bearing. The most important magnetic bearing principles are studied and the magnetic bearing developed by Escola Politécnica of São Paulo University (EPUSP-MB) is elected because of its very simple architecture. Besides presenting the principle of the EPUSP-MB, this work presents one possible alternative for applying the EPUSP-MB in the IDPC-VAD.

Control rod shutdown system

International Nuclear Information System (INIS)

Miyamoto, Yoshiyuki; Higashigawa, Yuichi.

1996-01-01

The present invention provides a control rod terminating system in a BWR type nuclear power plant, which stops an induction electric motor as rapidly as possible to terminate the control rods. Namely, the control rod stopping system controls reactor power by inserting/withdrawing control rods into a reactor by driving them by the induction electric motor. The system is provided with a control device for controlling the control rods and a control device for controlling the braking device. The control device outputs a braking operation signal for actuating the braking device during operation of the control rods to stop the operation of the control rods. Further, the braking device has at least two kinds of breaks, namely, a first and a second brakes. The two kinds of brakes are actuated by receiving the brake operation signals at different timings. The brake device is used also for keeping the control rods after the stopping. Even if a stopping torque of each of the breaks is small, different two kinds of brakes are operated at different timings thereby capable of obtaining a large stopping torque as a total. (I.S.)

Drone Control System

Science.gov (United States)

1983-01-01

Drones, subscale vehicles like the Firebees, and full scale retired military aircraft are used to test air defense missile systems. The DFCS (Drone Formation Control System) computer, developed by IBM (International Business Machines) Federal Systems Division, can track ten drones at once. A program called ORACLS is used to generate software to track and control Drones. It was originally developed by Langley and supplied by COSMIC (Computer Software Management and Information Center). The program saved the company both time and money.

Tautological control systems

CERN Document Server

Lewis, Andrew D

2014-01-01

This brief presents a description of a new modelling framework for nonlinear/geometric control theory. The framework is intended to be—and shown to be—feedback-invariant. As such, Tautological Control Systems provides a platform for understanding fundamental structural problems in geometric control theory. Part of the novelty of the text stems from the variety of regularity classes, e.g., Lipschitz, finitely differentiable, smooth, real analytic, with which it deals in a comprehensive and unified manner. The treatment of the important real analytic class especially reflects recent work on real analytic topologies by the author. Applied mathematicians interested in nonlinear and geometric control theory will find this brief of interest as a starting point for work in which feedback invariance is important. Graduate students working in control theory may also find Tautological Control Systems to be a stimulating starting point for their research.

Spacecraft momentum control systems

CERN Document Server

Leve, Frederick A; Peck, Mason A

2015-01-01

The goal of this book is to serve both as a practical technical reference and a resource for gaining a fuller understanding of the state of the art of spacecraft momentum control systems, specifically looking at control moment gyroscopes (CMGs). As a result, the subject matter includes theory, technology, and systems engineering. The authors combine material on system-level architecture of spacecraft that feature momentum-control systems with material about the momentum-control hardware and software. This also encompasses material on the theoretical and algorithmic approaches to the control of space vehicles with CMGs. In essence, CMGs are the attitude-control actuators that make contemporary highly agile spacecraft possible. The rise of commercial Earth imaging, the advances in privately built spacecraft (including small satellites), and the growing popularity of the subject matter in academic circles over the past decade argues that now is the time for an in-depth treatment of the topic. CMGs are augmented ...

Vacuum control system of VEC

International Nuclear Information System (INIS)

Roy, Anindya; Bhole, R.B.; Bandopadhyay, D.L.; Mukhopadhyay, B.; Pal, Sarbajit; Sarkar, D.

2009-01-01

As a part of modernization of VEC (Variable Energy Cyclotron), the Vacuum Control System is being upgraded to PLC based automated system from initial Relay based Manual system. EPICS (Experimental Physics and Industrial Control System), a standard open source software tool for designing distributed control system, is chosen for developing the supervisory control software layer, leading towards a unified distributed control architecture of VEC Control System. A Modbus - TCP based IOC (I/O Controller) has been developed to communicate control data to PLC using Ethernet-TCP LAN. Keeping in mind, the operators' familiarity with MS-Windows, a MS-Windows based operator interface is developed using VB6. It is also used to test and evaluate EPICS compatibility to MS Windows. Several MS Windows ActiveX components e.g. text display, image display, alarm window, set-point input etc. have been developed incorporating Channel Access library of EPICS. Use of such components ease the programming complexity and reduce developmental time of the operator interface. The system is in the final phase of commissioning. (author)

Researching on YH100 Numerical Control Servo Press Hydraulic Control System and Control Algorithm

Directory of Open Access Journals (Sweden)

Kai LI

2014-09-01

Full Text Available In order to study the numerical control (NC servo press hydraulic control system and its control algorithm. The numerical control servo press performance and control principle of hydraulic control system are analyzed. According to the flow equation of the hydraulic control valve, hydraulic cylinder flow continuity equation and the force balance equation of the hydraulic cylinder with load press, the mathematical model of hydraulic control system is established. And the servo press hydraulic system transfer function is deduced. Introducing the suitable immune particle swarm control algorithm for servo press hydraulic system, and the control system block diagram is established. Immune algorithm is used to optimize new control parameters of the system and adopt the new optimization results to optimize the system simulation. The simulation result shows that the hydraulic system’s transition time controlled by the immune particle swarm algorithm is shorter than traditional ones, and the control performance is obviously improved. Finally it can be concluded that immune particle swarm PID control have these characteristics such as quickness, stability and accuracy. Applying this principle into application, the obtained YH100 numerical control servo press hydraulic control system meets the requirement.

Outcomes of ventricular assist device implantation in children and young adults: the Melbourne experience.

Science.gov (United States)

Shi, William Y; Marasco, Silvana F; Saxena, Pankaj; d'Udekem, Yves; Yong, Matthew S; Mitnovetski, Sergei; Brizard, Christian P; McGiffin, David C; Weintraub, Robert G; Konstantinov, Igor E

2016-12-01

We evaluated our experience with ventricular assist device (VAD) implantation in children and young adults. A total of 64 patients underwent VAD implantation in two centres. The mean age was 15 ± 7.2 years. Thirty-five (55%) patients were under 18 years of age. Devices implanted included the Thoratec Paracorporeal in 30 (47%) patients, Berlin Heart EXCOR in 11 (17%) and VentrAssist in 14 (22%). The diagnosis was cardiomyopathy in 53, congenital heart disease in 11, and graft failure in four patients. There were 10 (16%) in-hospital deaths. Mortality was higher in patients <18 years of age (26% compared with 3.4% for those ≥18 years, P = 0.02). The use of extracorporeal membrane oxygenation prior to VAD implantation was associated with higher mortality (P = 0.006). Seventeen (27%) patients experienced stroke. Nine patients (14%) required change of VAD because of thrombosis. Transplantation was performed in 44 patients after a mean of 131 ± 141 days on VAD, 11 patients died without transplantation and three patients currently await transplantation. The VAD was explanted in six patients because of recovery. Overall survival from VAD implantation was 69% and 61% at 5 and 10 years, respectively. The 5-year post-transplant survival for those bridged with VAD support was 91% and was comparable with a cohort of patients who did not receive a pre-transplant VAD. Children requiring pre-transplant VAD support have a higher mortality and morbidity compared with young adults. Survival after heart transplantation those supported with VADs was similar to patients of similar age who did not require pre-transplant support. © 2015 Royal Australasian College of Surgeons.

Cost-Effectiveness of Ventricular Assist Device Destination Therapy for Advanced Heart Failure in Duchenne Muscular Dystrophy.

Science.gov (United States)

Magnetta, Defne A; Kang, JaHyun; Wearden, Peter D; Smith, Kenneth J; Feingold, Brian

2018-05-17

Destination ventricular assist device therapy (DT-VAD) is well accepted in select adults with medically refractory heart failure (HF) who are not transplant candidates; however, its use in younger patients with progressive diseases is unclear. We sought to evaluate the cost-effectiveness of DT-VAD in Duchenne muscular dystrophy (DMD) patients with advanced HF. We created a Markov-state transition model (5-year horizon) to compare survival, costs, and quality of life (QOL) between medical management and DT-VAD in DMD with advanced HF. Model input parameters were derived from the literature. We used sensitivity analyses to explore uncertainty around model assumptions. DT-VAD had higher costs ($435,602 vs. $125,696), survival (3.13 vs. 0.60 years), and quality-adjusted survival (1.99 vs. 0.26 years) than medical management. The incremental cost-effectiveness ratio (ICER) for DT-VAD was $179,086 per quality-adjusted life year (QALY). In sensitivity analyses that were widely varied to account for uncertainty in model assumptions, the DT-VAD strategy generally remained more costly and effective than medical management. Only when VAD implantation costs were <$113,142 did the DT-VAD strategy fall below the $100,000/QALY willingness-to-pay threshold commonly considered to be "cost-effective." In this exploratory analysis, DT-VAD for patients with DMD and advanced HF exceeded societal expectations for cost-effectiveness but had an ICER similar to the accepted practice of DT-VAD in adult HF patients. While more experience and research in this population is needed, our analysis suggests that DT-VAD for advanced HF in DMD should not be dismissed solely based on cost.

ISABELLE control system

International Nuclear Information System (INIS)

Humphrey, J.W.; Frankel, R.S.; Niederer, J.A.

1980-01-01

Design principles for the Brookhaven ISABELLE control intersecting storage ring accelerator are described. Principal features include a locally networked console and control computer complex, a system wide process data highway, and intelligent local device controllers. Progress to date is summarized

Replacement of the complete control system of the NPP Oskarshamn 1 by digital distributed control system

International Nuclear Information System (INIS)

Berger, E.

1998-01-01

As part of an ongoing modernization program, Oskarshamn 1's I and C system and control room will be upgraded by ABB using its Advant Power range of digital, programmable process control system. Besides ensuring the higher level of safety that is demanded today, the new equipment provides the plant with an integrated system which will improve operator overview of operation and reduce risk of human error and serve as a platform for further improvements of the control room. This paper discusses in the example of Oskarshamn 1 how the complete control system of a nuclear power plant may be exchanged, the technical solution and the time schedule. Oskarshamn 1 is the first nuclear power plant in Sweden. It is a boiling water reactor built by ABB ATOM in Sweden between 1966 and 1971. According to this age the control system is semiconductor based and the reactor protection system is relays based. This makes the maintenance expensive and extensions nearly impossible. To extend the life period of this plant the owner has decided to improve the safety system and to replace the reactor protection system and safety related control and the non safety related control by a state of the art digital distributed control system of ABB. In March 1997 ABB got the order to replace the reactor protection system, the safety control system, to start the replacement of all control systems and to replace the old control room by a new ergonomically designed control room. Together with the exchange of the control system an enhancement of the safety system and of the emergency power supply will be implemented

Phase Control in Nonlinear Systems

Science.gov (United States)

Zambrano, Samuel; Seoane, Jesús M.; Mariño, Inés P.; Sanjuán, Miguel A. F.; Meucci, Riccardo

The following sections are included: * Introduction * Phase Control of Chaos * Description of the model * Numerical exploration of phase control of chaos * Experimental evidence of phase control of chaos * Phase Control of Intermittency in Dynamical Systems * Crisis-induced intermittency and its control * Experimental setup and implementation of the phase control scheme * Phase control of the laser in the pre-crisis regime * Phase control of the intermittency after the crisis * Phase control of the intermittency in the quadratic map * Phase Control of Escapes in Open Dynamical Systems * Control of open dynamical systems * Model description * Numerical simulations and heuristic arguments * Experimental implementation in an electronic circuit * Conclusions and Discussions * Acknowledgments * References

Underwater hydraulic shock shovel control system

Science.gov (United States)

Liu, He-Ping; Luo, A.-Ni; Xiao, Hai-Yan

2008-06-01

The control system determines the effectiveness of an underwater hydraulic shock shovel. This paper begins by analyzing the working principles of these shovels and explains the importance of their control systems. A new type of control system’s mathematical model was built and analyzed according to those principles. Since the initial control system’s response time could not fulfill the design requirements, a PID controller was added to the control system. System response time was still slower than required, so a neural network was added to nonlinearly regulate the proportional element, integral element and derivative element coefficients of the PID controller. After these improvements to the control system, system parameters fulfilled the design requirements. The working performance of electrically-controlled parts such as the rapidly moving high speed switch valve is largely determined by the control system. Normal control methods generally can’t satisfy a shovel’s requirements, so advanced and normal control methods were combined to improve the control system, bringing good results.

The ATLAS Detector Control System

International Nuclear Information System (INIS)

Lantzsch, K; Braun, H; Hirschbuehl, D; Kersten, S; Arfaoui, S; Franz, S; Gutzwiller, O; Schlenker, S; Tsarouchas, C A; Mindur, B; Hartert, J; Zimmermann, S; Talyshev, A; Oliveira Damazio, D; Poblaguev, A; Martin, T; Thompson, P D; Caforio, D; Sbarra, C; Hoffmann, D

2012-01-01

The ATLAS experiment is one of the multi-purpose experiments at the Large Hadron Collider (LHC) at CERN, constructed to study elementary particle interactions in collisions of high-energy proton beams. Twelve different sub detectors as well as the common experimental infrastructure are controlled and monitored by the Detector Control System (DCS) using a highly distributed system of 140 server machines running the industrial SCADA product PVSS. Higher level control system layers allow for automatic control procedures, efficient error recognition and handling, manage the communication with external systems such as the LHC controls, and provide a synchronization mechanism with the ATLAS data acquisition system. Different databases are used to store the online parameters of the experiment, replicate a subset used for physics reconstruction, and store the configuration parameters of the systems. This contribution describes the computing architecture and software tools to handle this complex and highly interconnected control system.

The ATLAS Detector Control System

Science.gov (United States)

Lantzsch, K.; Arfaoui, S.; Franz, S.; Gutzwiller, O.; Schlenker, S.; Tsarouchas, C. A.; Mindur, B.; Hartert, J.; Zimmermann, S.; Talyshev, A.; Oliveira Damazio, D.; Poblaguev, A.; Braun, H.; Hirschbuehl, D.; Kersten, S.; Martin, T.; Thompson, P. D.; Caforio, D.; Sbarra, C.; Hoffmann, D.; Nemecek, S.; Robichaud-Veronneau, A.; Wynne, B.; Banas, E.; Hajduk, Z.; Olszowska, J.; Stanecka, E.; Bindi, M.; Polini, A.; Deliyergiyev, M.; Mandic, I.; Ertel, E.; Marques Vinagre, F.; Ribeiro, G.; Santos, H. F.; Barillari, T.; Habring, J.; Huber, J.; Arabidze, G.; Boterenbrood, H.; Hart, R.; Iakovidis, G.; Karakostas, K.; Leontsinis, S.; Mountricha, E.; Ntekas, K.; Filimonov, V.; Khomutnikov, V.; Kovalenko, S.; Grassi, V.; Mitrevski, J.; Phillips, P.; Chekulaev, S.; D'Auria, S.; Nagai, K.; Tartarelli, G. F.; Aielli, G.; Marchese, F.; Lafarguette, P.; Brenner, R.

2012-12-01

The ATLAS experiment is one of the multi-purpose experiments at the Large Hadron Collider (LHC) at CERN, constructed to study elementary particle interactions in collisions of high-energy proton beams. Twelve different sub detectors as well as the common experimental infrastructure are controlled and monitored by the Detector Control System (DCS) using a highly distributed system of 140 server machines running the industrial SCADA product PVSS. Higher level control system layers allow for automatic control procedures, efficient error recognition and handling, manage the communication with external systems such as the LHC controls, and provide a synchronization mechanism with the ATLAS data acquisition system. Different databases are used to store the online parameters of the experiment, replicate a subset used for physics reconstruction, and store the configuration parameters of the systems. This contribution describes the computing architecture and software tools to handle this complex and highly interconnected control system.

Hybrid spacecraft attitude control system

OpenAIRE

Renuganth Varatharajoo; Ramly Ajir; Tamizi Ahmad

2016-01-01

The hybrid subsystem design could be an attractive approach for futurespacecraft to cope with their demands. The idea of combining theconventional Attitude Control System and the Electrical Power System ispresented in this article. The Combined Energy and Attitude ControlSystem (CEACS) consisting of a double counter rotating flywheel assemblyis investigated for small satellites in this article. Another hybrid systemincorporating the conventional Attitude Control System into the ThermalControl...

Tuning method for multi-variable control system with PID controllers

International Nuclear Information System (INIS)

Fujiwara, Toshitaka

1983-01-01

Control systems, including thermal and nuclear power plants, generally and mainly use PID controllers consisting of proportional, integral and differential actions. These systems consist of multiple control loops which interfere with each other. Therefore, it is present status that the fine control of the system is carried out by the trial and error method because the adjusting procedure for a single control loop cannot be applied to a multi-loop system in most cases. In this report, a method to effectively adjust PID controller parameters in a short time in a control system which consists of multi-loops that interfere with each other. This method makes adjustment by using the control area as the evaluation function, which is the time-dependent integration of control deviation, the input to the PID controllers. In other words, the evaluation function is provided for each control result for every parameter (gain constant, reset rate, and differentiation time), and all parameters are simultaneously changed in the direction of minimizing the values of these evaluation functions. In the report, the principle of tuning method, the evaluation function for each of three parameters, and the adjusting system configuration for separately using for actual plant tuning and for control system design are described. It also shows the examples of application to the actual tuning of the control system for a thermal power plant and to a control system design. (Wakatsuki, Y.)

Replacement of the complete control system of the NPP Oskarshamn 1 by digital distributed control system

International Nuclear Information System (INIS)

Berger, E.

1998-01-01

As part of an ongoing modernization program, the I and C system and the control room of Oskarshamn 1 will be upgraded by ABB using its 'Advant Power' range of digital, programmable process control system. Besides ensuring the higher level of safety that is demanded today, the new equipment provides the plant with an integrated system which will improve operator interaction with the plant and reduce the risk of human error. The newly installed DCS system will serve also as a platform for further improvements of the control room. This paper discusses Oskarshamn 1 exchange of the complete control system of a nuclear power plant, the technical solution and the time schedule. Oskarshamn 1 is the first nuclear power plant in Sweden. It is a boiling water reactor built between 1966 and 1971 by ABB ATOM in Sweden. According to the plant age the control system is relay-based, while instrumentation and analogue control is semiconductor-based. This makes maintenance expensive and even worse, makes extensions nearly impossible. According to the safety standards of the 1960s, there is no separation between safety and non safety control and no seismic qualification. To extend the life of this plant the owner has decided to improve the safety system as well as to replace the reactor protection system, the safety related control and the non safety related control by a state-of-the-art digital distributed control system from ABB. In March 1997, ABB got the order to replace the reactor protection system, the safety control system and to start the replacement of all control systems. The old control room has to be replaced by a new ergonomically design. Together with the exchange of the control system the safety features of the plant and the emergency power supply has to be extended. (author)

Manufacturing systems considered as time domain control systems : receding horizon control and observers

NARCIS (Netherlands)

Roset, B.J.P.

2007-01-01

This thesis considers manufacturing systems and model-based controller design, as well as their combinations. The objective of a manufacturing system is to create products from a selected group of raw materials and semifinished goods. In the field of manufacturing systems control is an important

neural control system

International Nuclear Information System (INIS)

Elshazly, A.A.E.

2002-01-01

Automatic power stabilization control is the desired objective for any reactor operation , especially, nuclear power plants. A major problem in this area is inevitable gap between a real plant ant the theory of conventional analysis and the synthesis of linear time invariant systems. in particular, the trajectory tracking control of a nonlinear plant is a class of problems in which the classical linear transfer function methods break down because no transfer function can represent the system over the entire operating region . there is a considerable amount of research on the model-inverse approach using feedback linearization technique. however, this method requires a prices plant model to implement the exact linearizing feedback, for nuclear reactor systems, this approach is not an easy task because of the uncertainty in the plant parameters and un-measurable state variables . therefore, artificial neural network (ANN) is used either in self-tuning control or in improving the conventional rule-based exper system.the main objective of this thesis is to suggest an ANN, based self-learning controller structure . this method is capable of on-line reinforcement learning and control for a nuclear reactor with a totally unknown dynamics model. previously, researches are based on back- propagation algorithm . back -propagation (BP), fast back -propagation (FBP), and levenberg-marquardt (LM), algorithms are discussed and compared for reinforcement learning. it is found that, LM algorithm is quite superior

RHIC control system

Energy Technology Data Exchange (ETDEWEB)

Barton, D.S. E-mail: dsbarton@bnl.gov; Binello, S.; Buxton, W.; Clifford, T.; D' Ottavio, T.; Hartmann, H.; Hoff, L.T.; Katz, R.; Kennell, S.; Kerner, T.; Laster, J.; Lee, R.C.; Marusic, A.; Michnoff, R.; Morris, J.; Oerter, B.R.; Olsen, R.; Piacentino, J.; Skelly, J.F

2003-03-01

The RHIC control system architecture is hierarchical and consists of two physical layers with a fiber-optic network connection. The Front-End Level systems consist of VME chassis with processors running a real-time operating system and both VME I/O modules and remote bus interfaces. Accelerator device software interfaces are implemented as objects in C++. The network implementation uses high speed, switched Ethernet technology. Specialized hardware modules were built for waveform control of power supplies, multiplexed signal acquisition, and timing services. The Console Level systems are Unix workstations. A strong emphasis has been given to developing highly reusable, standard software tools for use in building physics and diagnostic application software.

RHIC control system

International Nuclear Information System (INIS)

Barton, D.S.; Binello, S.; Buxton, W.; Clifford, T.; D'Ottavio, T.; Hartmann, H.; Hoff, L.T.; Katz, R.; Kennell, S.; Kerner, T.; Laster, J.; Lee, R.C.; Marusic, A.; Michnoff, R.; Morris, J.; Oerter, B.R.; Olsen, R.; Piacentino, J.; Skelly, J.F.

2003-01-01

The RHIC control system architecture is hierarchical and consists of two physical layers with a fiber-optic network connection. The Front-End Level systems consist of VME chassis with processors running a real-time operating system and both VME I/O modules and remote bus interfaces. Accelerator device software interfaces are implemented as objects in C++. The network implementation uses high speed, switched Ethernet technology. Specialized hardware modules were built for waveform control of power supplies, multiplexed signal acquisition, and timing services. The Console Level systems are Unix workstations. A strong emphasis has been given to developing highly reusable, standard software tools for use in building physics and diagnostic application software

Sociālo tīklu izmantošana pusaudžu vecumā un to vadīšanas iespējas interešu izglītībā

OpenAIRE

Biezais, Artūrs

2015-01-01

Pētījuma nosaukums ir „Sociālo tīklu izmantošana pusaudžu vecumā un to vadīšanas iespējas interešu izglītībā”. Dažādos pētījumos ir pierādīts, ka tieši pusaudžu vecumposms ir tas, kurā bērni visvairāk laika pavada sociālajos tīklos. Viņi tiem piekļūst ar datoru, ar viedtālruņu un planšetdatoru palīdzību. Neskatoties uz to, ka bērni sociālos tīklus ļoti aktīvi izmanto ārpus skolas, viņi tos izmanto arī skolā un pat mācību stundās. Tā ir mūsdienu realitāte, kas visnotaļ, atkarībā no sociālo med...

Control of Solar Energy Systems

CERN Document Server

Camacho, Eduardo F; Rubio, Francisco R; Martínez, Diego

2012-01-01

Control of Solar Energy Systems details the main solar energy systems, problems involved with their control, and how control systems can help in increasing their efficiency.  After a brief introduction to the fundamental concepts associated with the use of solar energy in both photovoltaic and thermal plants, specific issues related to control of solar systems are embarked upon. Thermal energy systems are then explored in depth, as well as  other solar energy applications such as solar furnaces and solar refrigeration systems. Problems of variable generation profile and of the contribution of many solar plants to the same grid system are considered with the necessary integrated and supervisory control solutions being discussed. The text includes material on: ·         A comparison of basic and advanced control methods for parabolic troughs from PID to nonlinear model-based control; ·         solar towers and solar tracking; ·         heliostat calibration, characterization and off...

[Prevalence of vitamin a deficiency and anemia in children under five years of age in Peru].

Science.gov (United States)

Pajuelo, Jaime; Miranda, Marianella; Zamora, Rosa

2015-01-01

To determine the prevalence of vitamin A deficiency (VAD) and nutritional anemia (NA) in children under five in Peru. Cross-sectional study with a stratified and multi-staged probabilistic sample conducted between November 2007 and April 2010.2,736 children were included for NA and 1,465 children for VAD. NA was defined as Hb<11 g/dL.VAD was identified by serum retinol levels <20 µg/dL. Sociodemographic variables related to the child and the mother were studied in addition to their participation in growth control and development programs, integrated nutrition program and supplementation with iron and vitamin A. Analysis of complex samples was performed, descriptive statistics and logistic regression with 95% confidence intervals and a significance level of p<0.05 were calculated. The prevalence of VAD was 11.7% (95% CI: 9.4 to 14.4). The highest prevalences were in children under five months (44.6%) and those living in rural areas (19.5%). The prevalence of NA was 33% (95% CI: 29.9 to 36.1) and was higher in children under 11 months (68.2%) and children of mothers aged 13-19 years old (55.4 %). VAD is a public health problem that remains, with the most affected children living in rural areas and in the jungle. The prevalence of NA shows a slight improvement. It is necessary to improve the efficiency and impact of programs that include supplementation of vitamin A and iron.

Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia.

Science.gov (United States)

Moretti, Rita; Caruso, Paola; Dal Ben, Matteo; Conti, Corrado; Gazzin, Silvia; Tiribelli, Claudio

2017-01-01

Dementia is a worldwide health problem which affects millions of patients; Alzheimer's disease (AD) and subcortical vascular dementia (sVAD) are the two most frequent forms of its presentation. As no definite therapeutic options have been discovered, different risk factors for cognitive impairment have been searched for potential therapies. This report focuses on the possible evidence that vitamin D deficiency and hyper-homocysteinemia can be considered as two important factors for the development or the progression of neurodegenerative or vascular pathologies. To this end, we assessed: the difference in vascular risk factors and vitamin D-OH25 levels among groups of sVAD, AD, and healthy age-matched controls; the association of folate, B12, homocysteine, and vitamin D with sVAD/AD and whether a deficiency of vitamin D and an increment in homocysteine levels may be related to neurodegenerative or vessel damages. The commonly-considered vascular risk factors were collected in 543 patients and compared with those obtained from a healthy old volunteer population. ANOVA group comparison showed that vitamin D deficiency was present in demented cases, as well as low levels of folate and high levels of homocysteine, more pronounced in sVAD cases. The statistical models we employed, with regression models built, and adjustments for biochemical, demographic and neuropsychiatric scores, confirmed the association between the three measures (folate decrease, hyperhomocysteinemia and vitamin D decrease) and dementia, more pronounced in sVAD than in AD.

Multicopter control with Navio using REX control system

Science.gov (United States)

Golembiovsky, Matej; Dedek, Jan; Ozana, Stepan

2017-06-01

This article deals with study of possible connection of the REXcontrols platform with Raspberry Pi based control system and Navio2 expansion board. This board is designed for development of autonomous robotic platforms type car, plane or multicopter. In this article, control system REXcontrols is introduced and its integration possibilities for control board Navio2 are discussed. The main discussed aspects are communication possibilities of the REXcontrols system with external scripts which further on allow control of this board. The main reasons for this undertaking are vast possibilities of archiving, visualization, signal processing and control which REXcontrols system allows. The control itself of the navio2 board is done through numerous interfaces. Specifically it is a pair of SPI data buses, an I2C data bus, UART and multiple GPIO pins. However, since REXcontrols control system has only limited access to these data buses, it is necessary to establish the communication through external scripts. For this purpose REXcontrols is equipped with mechanisms; SILO, EPC and REXLANG which are described in the article. Due to its simple implementation into REXcontrols and the option to utilize available libraries for communication with Navio2 board in external script, an EPC block was selected for the final implementation.

TMX magnet control system

International Nuclear Information System (INIS)

Goerz, D.A.

1978-01-01

A control system utilizing a microcomputer has been developed that controls the power supplies driving the Tandem Mirror Experiment (TMX) magnet set and monitors magnet coil operation. The magnet set consists of 18 magnet coils that are driven by 26 dc power supplies. There are two possible modes of operation with this system: a pulse mode where the coils are pulsed on for several seconds with a dc power consumption of 16 MW; and a continuous mode where the coils can run steady state at 10 percent of maximum current ratings. The processor has been given an active control role and serves as an interface between the operator and electronic circuitry that controls the magnet power supplies. This microcomputer also collects and processes data from many analog singal monitors in the coil circuits and numerous status signals from the supplies. Placing the microcomputer in an active control role has yielded a compact, cost effective system that simplifies the magnet system operation and has proven to be very reliable. This paper will describe the TMX magnet control sytem and discuss its development

Observer-Based Robust Control for Hydraulic Velocity Control System

Directory of Open Access Journals (Sweden)

Wei Shen

2013-01-01

Full Text Available This paper investigates the problems of robust stabilization and robust control for the secondary component speed control system with parameters uncertainty and load disturbance. The aim is to enhance the control performance of hydraulic system based on Common Pressure Rail (CPR. Firstly, a mathematical model is presented to describe the hydraulic control system. Then a novel observer is proposed, and an observed-based control strategy is designed such that the closed-loop system is asymptotically stable and satisfies the disturbance attenuation level. The condition for the existence of the developed controller can by efficiently solved by using the MATLAB software. Finally, simulation results are provided to demonstrate the effectiveness of the proposed method.

An Estimate of Attributable Cases of Alzheimer Disease and Vascular Dementia due to Modifiable Risk Factors: The Impact of Primary Prevention in Europe and in Italy

Directory of Open Access Journals (Sweden)

Flavia Mayer

2018-02-01

Full Text Available Background: Up to 53.7% of all cases of dementia are assumed to be due to Alzheimer disease (AD, while 15.8% are considered to be due to vascular dementia (VaD. In Europe, about 3 million cases of AD could be due to 7 potentially modifiable risk factors: diabetes, midlife hypertension and/or obesity, physical inactivity, depression, smoking, and low educational level. Aims: To estimate the number of VaD cases in Europe and the number of AD and VaD cases in Italy attributable to these 7 potentially modifiable risk factors. Methods: Assuming the nonindependence of the 7 risk factors, the adjusted combined population attributable risk (PAR was estimated for AD and VaD. Results: In Europe, adjusted combined PAR was 31.4% for AD and 37.8% for VaD. The total number of attributable cases was 3,033,000 for AD and 873,000 for VaD. In Italy, assuming a 20% reduction of the prevalence of each risk factor, adjusted combined PAR decreased from 45.2 to 38.9% for AD and from 53.1 to 46.6% for VaD, implying a 6.4 and 6.5% reduction in the prevalence of AD and VaD, respectively. Conclusion: A relevant reduction of AD and VaD cases in Europe and Italy could be obtained through primary prevention.

An Estimate of Attributable Cases of Alzheimer Disease and Vascular Dementia due to Modifiable Risk Factors: The Impact of Primary Prevention in Europe and in Italy.

Science.gov (United States)

Mayer, Flavia; Di Pucchio, Alessandra; Lacorte, Eleonora; Bacigalupo, Ilaria; Marzolini, Fabrizio; Ferrante, Gianluigi; Minardi, Valentina; Masocco, Maria; Canevelli, Marco; Di Fiandra, Teresa; Vanacore, Nicola

2018-01-01

Up to 53.7% of all cases of dementia are assumed to be due to Alzheimer disease (AD), while 15.8% are considered to be due to vascular dementia (VaD). In Europe, about 3 million cases of AD could be due to 7 potentially modifiable risk factors: diabetes, midlife hypertension and/or obesity, physical inactivity, depression, smoking, and low educational level. To estimate the number of VaD cases in Europe and the number of AD and VaD cases in Italy attributable to these 7 potentially modifiable risk factors. Assuming the nonindependence of the 7 risk factors, the adjusted combined population attributable risk (PAR) was estimated for AD and VaD. In Europe, adjusted combined PAR was 31.4% for AD and 37.8% for VaD. The total number of attributable cases was 3,033,000 for AD and 873,000 for VaD. In Italy, assuming a 20% reduction of the prevalence of each risk factor, adjusted combined PAR decreased from 45.2 to 38.9% for AD and from 53.1 to 46.6% for VaD, implying a 6.4 and 6.5% reduction in the prevalence of AD and VaD, respectively. A relevant reduction of AD and VaD cases in Europe and Italy could be obtained through primary prevention.

How the factoid of wind turbines causing 'vibroacoustic disease' came to be 'irrefutably demonstrated'.

Science.gov (United States)

Chapman, Simon; St George, Alexis

2013-06-01

In recent years, claims have proliferated in cyberspace that wind turbines cause a large variety of symptoms and diseases. One of these, "vibroacoustic disease" (VAD) is frequently mentioned. The aim of this study is to examine the quality of the evidence on how VAD came to be associated with wind turbine exposure by wind farm opponents. Searches of the web (Google advanced) and major research databases for papers on VAD and wind turbines. Self-citation analysis of research papers on VAD. Google returned 24,700 hits for VAD and wind turbines. Thirty-five research papers on VAD were found, none reporting any association between VAD and wind turbines. Of the 35 papers, 34 had a first author from a single Portuguese research group. Seventy-four per cent of citations to these papers were self-citations by the group. Median self-citation rates in science are around 7%. Two unpublished case reports presented at conferences were found asserting that VAD was "irrefutably demonstrated" to be caused by wind turbines. The quality of these reports was abject. VAD has received virtually no scientific recognition beyond the group who coined and promoted the concept. There is no evidence of even rudimentary quality that vibroacoustic disease is associated with or caused by wind turbines. The claim that wind turbines cause VAD is a factoid that has gone 'viral' in cyberspace and may be contributing to nocebo effects among those living near turbines. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.

Reset Control Systems

CERN Document Server

Baños, Alfonso

2012-01-01

Reset Control Systems addresses the analysis for reset control treating both its basic form which requires only that the state of the controller be reinitialized to zero (the reset action) each time the tracking error crosses zero (the reset condition), and some useful variations of the reset action (partial reset with fixed or variable reset percentage) and of the reset condition (fixed or variable reset band and anticipative reset). The issues regarding reset control – concepts and motivation; analysis tools; and the application of design methodologies to real-world examples – are given comprehensive coverage. The text opens with an historical perspective which moves from the seminal work of the Clegg integrator and Horowitz FORE to more recent approaches based on impulsive/hybrid control systems and explains the motivation for reset compensation. Preliminary material dealing with notation, basic definitions and results, and with the definition of the control problem under study is also included. The fo...

Delays and networked control systems

CERN Document Server

Hetel, Laurentiu; Daafouz, Jamal; Johansson, Karl

2016-01-01

This edited monograph includes state-of-the-art contributions on continuous time dynamical networks with delays. The book is divided into four parts. The first part presents tools and methods for the analysis of time-delay systems with a particular attention on control problems of large scale or infinite-dimensional systems with delays. The second part of the book is dedicated to the use of time-delay models for the analysis and design of Networked Control Systems. The third part of the book focuses on the analysis and design of systems with asynchronous sampling intervals which occur in Networked Control Systems. The last part of the book exposes several contributions dealing with the design of cooperative control and observation laws for networked control systems. The target audience primarily comprises researchers and experts in the field of control theory, but the book may also be beneficial for graduate students. .

Distributed systems status and control

Science.gov (United States)

Kreidler, David; Vickers, David

1990-01-01

Concepts are investigated for an automated status and control system for a distributed processing environment. System characteristics, data requirements for health assessment, data acquisition methods, system diagnosis methods and control methods were investigated in an attempt to determine the high-level requirements for a system which can be used to assess the health of a distributed processing system and implement control procedures to maintain an accepted level of health for the system. A potential concept for automated status and control includes the use of expert system techniques to assess the health of the system, detect and diagnose faults, and initiate or recommend actions to correct the faults. Therefore, this research included the investigation of methods by which expert systems were developed for real-time environments and distributed systems. The focus is on the features required by real-time expert systems and the tools available to develop real-time expert systems.

Post-transplant outcomes in pediatric ventricular assist device patients: A PediMACS-Pediatric Heart Transplant Study linkage analysis.

Science.gov (United States)

Sutcliffe, David L; Pruitt, Elizabeth; Cantor, Ryan S; Godown, Justin; Lane, John; Turrentine, Mark W; Law, Sabrina P; Lantz, Jodie L; Kirklin, James K; Bernstein, Daniel; Blume, Elizabeth D

2017-12-13

Pediatric ventricular assist device (VAD) support as bridge to transplant has improved waitlist survival, but the effects of pre-implant status and VAD-related events on post-transplant outcomes have not been assessed. This study is a linkage analysis between the PediMACS and Pediatric Heart Transplant Study databases to determine the effects of VAD course on post-transplant outcomes. Database linkage between October 1, 2012 and December 31, 2015 identified 147 transplanted VAD patients, the primary study group. The comparison cohort was composed of 630 PHTS patients without pre-transplant VAD support. The primary outcome was post-transplant survival, with secondary outcomes of post-transplant length of stay, freedom from infection and freedom from rejection. At implant, the VAD cohort was INTERMACS Profile 1 in 33 (23%), Profile 2 in 89 (63%) and Profile 3 in 14 (10%) patients. The VAD cohort was older, larger, and less likely to have congenital heart disease (p < 0.0001). However, they had greater requirements for inotrope and ventilator support and increased liver and renal dysfunction (p < 0.0001), both of which normalized at transplant after device support. Importantly, there were no differences in 1-year post-transplant survival (96% vs 93%, p = 0.3), freedom from infection (81% vs 79%, p = 0.9) or freedom from rejection (71% vs 74%, p = 0.87) between cohorts. Pediatric VAD patients have post-transplant outcomes equal to that of medically supported patients, despite greater pre-implant illness severity. Post-transplant survival, hospital length of stay, infection and rejection were not affected by patient acuity at VAD implantation or VAD-related complications. Therefore, VAD as bridge to transplant mitigates severity of illness in children. Copyright © 2017 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Upgrading the BEPC control system

International Nuclear Information System (INIS)

Yang Liping; Wang Lizheng; Liu Shiyao

1992-01-01

The BEPC control system has been put into operation and operated normally since the end of 1987. Three years's experience shows this system can satisfy basically the operation requirements, also exhibits some disadvantages araised from the original centralized system architecture based on the VAX-VCC-CAMAC, such as slow response, bottle neck of VCC, less CPU power for control etc.. This paper describes the method and procedure for upgrading the BEPC control system which will be based on DEC net and DEC-WS, and thus intend to upgrade the control system architecture from the centralized to the distributed and improve the integral system performance. (author)

Characterization of gradient control systems

NARCIS (Netherlands)

Cortés, Jorge; van der Schaft, Arjan; Crouch, Peter E.

2005-01-01

Given a general nonlinear affine control system with outputs and a torsion-free affine connection defined on its state space, we investigate the gradient realization problem: we give necessary and sufficient conditions under which the control system can be written as a gradient control system

Characterization of Gradient Control Systems

NARCIS (Netherlands)

Cortés, Jorge; Schaft, Arjan van der; Crouch, Peter E.

2005-01-01

Given a general nonlinear affine control system with outputs and a torsion-free affine connection defined on its state space, we investigate the gradient realization problem: we give necessary and sufficient conditions under which the control system can be written as a gradient control system

Computer-aided control system design

International Nuclear Information System (INIS)

Lebenhaft, J.R.

1986-01-01

Control systems are typically implemented using conventional PID controllers, which are then tuned manually during plant commissioning to compensate for interactions between feedback loops. As plants increase in size and complexity, such controllers can fail to provide adequate process regulations. Multivariable methods can be utilized to overcome these limitations. At the Chalk River Nuclear Laboratories, modern control systems are designed and analyzed with the aid of MVPACK, a system of computer programs that appears to the user like a high-level calculator. The software package solves complicated control problems, and provides useful insight into the dynamic response and stability of multivariable systems

Coordination control of distributed systems

CERN Document Server

Villa, Tiziano

2015-01-01

This book describes how control of distributed systems can be advanced by an integration of control, communication, and computation. The global control objectives are met by judicious combinations of local and nonlocal observations taking advantage of various forms of communication exchanges between distributed controllers. Control architectures are considered according to  increasing degrees of cooperation of local controllers:  fully distributed or decentralized control,  control with communication between controllers,  coordination control, and multilevel control.  The book covers also topics bridging computer science, communication, and control, like communication for control of networks, average consensus for distributed systems, and modeling and verification of discrete and of hybrid systems. Examples and case studies are introduced in the first part of the text and developed throughout the book. They include: control of underwater vehicles, automated-guided vehicles on a container terminal, contro...

Weld analysis and control system

Science.gov (United States)

Kennedy, Larry Z. (Inventor); Rodgers, Michael H. (Inventor); Powell, Bradley W. (Inventor); Burroughs, Ivan A. (Inventor); Goode, K. Wayne (Inventor)

1994-01-01

The invention is a Weld Analysis and Control System developed for active weld system control through real time weld data acquisition. Closed-loop control is based on analysis of weld system parameters and weld geometry. The system is adapted for use with automated welding apparatus having a weld controller which is capable of active electronic control of all aspects of a welding operation. Enhanced graphics and data displays are provided for post-weld analysis. The system provides parameter acquisition, including seam location which is acquired for active torch cross-seam positioning. Torch stand-off is also monitored for control. Weld bead and parent surface geometrical parameters are acquired as an indication of weld quality. These parameters include mismatch, peaking, undercut, underfill, crown height, weld width, puddle diameter, and other measurable information about the weld puddle regions, such as puddle symmetry, etc. These parameters provide a basis for active control as well as post-weld quality analysis and verification. Weld system parameters, such as voltage, current and wire feed rate, are also monitored and archived for correlation with quality parameters.

Distributed process control system for remote control and monitoring of the TFTR tritium systems

International Nuclear Information System (INIS)

Schobert, G.; Arnold, N.; Bashore, D.; Mika, R.; Oliaro, G.

1989-01-01

This paper reviews the progress made in the application of a commercially available distributed process control system to support the requirements established for the Tritium REmote Control And Monitoring System (TRECAMS) of the Tokamak Fusion Test REactor (TFTR). The system that will discussed was purchased from Texas (TI) Instruments Automation Controls Division), previously marketed by Rexnord Automation. It consists of three, fully redundant, distributed process controllers interfaced to over 1800 analog and digital I/O points. The operator consoles located throughout the facility are supported by four Digital Equipment Corporation (DEC) PDP-11/73 computers. The PDP-11/73's and the three process controllers communicate over a fully redundant one megabaud fiber optic network. All system functionality is based on a set of completely integrated databases loaded to the process controllers and the PDP-11/73's. (author). 2 refs.; 2 figs

The remote control system

International Nuclear Information System (INIS)

Jansweijer, P.P.M.

1988-01-01

The remote-control system is applied in order to control various signals in the car of the spectrometer at distance. The construction (hardware and software) as well as the operation of the system is described. (author). 20 figs

Systems and Control Engineering

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 5. Systems and Control Engineering - Control Systems-Analysis and Design. A Rama Kalyan J R Vengateswaran. General Article Volume 4 Issue 5 May 1999 pp 88-94 ...

Documenting control system functionality for digital control implementations

International Nuclear Information System (INIS)

Harber, J.; Borairi, M.; Tikku, S.; Josefowicz, A.

2006-01-01

In past CANDU designs, plant control was accomplished by a combination of digital control computers, analogue controllers, and hardwired relay logic. Functionality for these various control systems, each using different hardware, was documented in varied formats such as text based program specifications, relay logic diagrams, and other various specification documents. The choice of formats was influenced by the hardware used and often required different specialized skills for different applications. The programmable electronic systems in new CANDU designs are realized in a manner consistent with latest international standards (e.g., the IEC 61513 standard). New CANDU designs make extensive use of modern digital control technology, with the benefit that functionality can be implemented on a limited number of control platforms, reducing development and maintenance cost. This approach can take advantage of tools that allow the plant control system functional and performance requirements to be documented using graphical representations. Modern graphical methods supplemented by information databases can be used to provide a clear and comprehensive set of requirements for software and system development. Overview diagrams of system functionality provide a common understanding of the system boundaries and interfaces. Important requirements are readily traced through the development process. This improved reviewability helps to ensure consistency with the safety and and production design requirements of the system. Encapsulation of commonly used functions into custom-defined function blocks, such as typical motor control centre interfaces, process interlocks, median selects etc, eases the burden on designers to understand and analyze the detailed functionality of each instance of use of this logic. A library of encapsulated functions will be established for complex functions that are reused in the control logic development. By encapsulation and standardisation of such

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

International Nuclear Information System (INIS)

C.J. Fernado

1998-01-01

The purpose of this document is to develop preliminary high-level functional and physical control system architectures for the proposed subsurface repository at Yucca Mountain. This document outlines overall control system concepts that encompass and integrate the many diverse systems being considered for use within the subsurface repository. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The subsurface repository design will be composed of a series of diverse systems that will be integrated to accomplish a set of overall functions and objectives. The subsurface repository contains several Instrumentation and Control (I andC) related systems including: waste emplacement systems, ventilation systems, communication systems, radiation monitoring systems, rail transportation systems, ground control monitoring systems, utility monitoring systems (electrical, lighting, water, compressed air, etc.), fire detection and protection systems, retrieval systems, and performance confirmation systems. Each of these systems involve some level of I andC and will typically be integrated over a data communication network. The subsurface I andC systems will also integrate with multiple surface-based site-wide systems such as emergency response, health physics, security and safeguards, communications, utilities and others. The scope and primary objectives of this analysis are to: (1) Identify preliminary system level functions and interface needs (Presented in the functional diagrams in Section 7.2). (2) Examine the overall system complexity and determine how and on what levels these control systems will be controlled and integrated (Presented in Section 7.2). (3) Develop a preliminary subsurface facility-wide design for an overall control system architecture, and depict this design by a series of control system functional block diagrams (Presented in Section 7.2). (4) Develop a series of physical architectures

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

Energy Technology Data Exchange (ETDEWEB)

C.J. Fernado

1998-09-17

The purpose of this document is to develop preliminary high-level functional and physical control system architectures for the proposed subsurface repository at Yucca Mountain. This document outlines overall control system concepts that encompass and integrate the many diverse systems being considered for use within the subsurface repository. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The subsurface repository design will be composed of a series of diverse systems that will be integrated to accomplish a set of overall functions and objectives. The subsurface repository contains several Instrumentation and Control (I&C) related systems including: waste emplacement systems, ventilation systems, communication systems, radiation monitoring systems, rail transportation systems, ground control monitoring systems, utility monitoring systems (electrical, lighting, water, compressed air, etc.), fire detection and protection systems, retrieval systems, and performance confirmation systems. Each of these systems involve some level of I&C and will typically be integrated over a data communication network. The subsurface I&C systems will also integrate with multiple surface-based site-wide systems such as emergency response, health physics, security and safeguards, communications, utilities and others. The scope and primary objectives of this analysis are to: (1) Identify preliminary system level functions and interface needs (Presented in the functional diagrams in Section 7.2). (2) Examine the overall system complexity and determine how and on what levels these control systems will be controlled and integrated (Presented in Section 7.2). (3) Develop a preliminary subsurface facility-wide design for an overall control system architecture, and depict this design by a series of control system functional block diagrams (Presented in Section 7.2). (4) Develop a series of physical architectures that

Design of a distributed control system

Energy Technology Data Exchange (ETDEWEB)

Bilous, O [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

1959-07-01

A digital computer is used to evaluate various pressure control systems for a gaseous diffusion cascade. This is an example of a distributed feedback control system. The paper gives a brief discussion of similar cases of distributed or stage wise control systems, which may occur in multiple temperature control of chemical processes. (author) [French] Une calculatrice digitale est utilisee pour evaluer divers systemes de controle de pression pour une cascade de diffusion gazeuse. C'est un exemple de systeme de controle a reaction distribue. Le rapport presente une breve discussion de cas semblables de systemes de controle distribues ou en etage, qui peuvent se presenter dans de nombreux controles de temperature de reactions chimiques. (auteur)

MULTIPLE ECH LAUNCHER CONTROL SYSTEM

International Nuclear Information System (INIS)

GREEN, M.T.; PONCE, D.; GRUNLOH, H.J.; ELLIS, R.A.; GROSNICKLE, W.H.; HUMPHREY, R.L.

2004-03-01

OAK-B135 The addition of new, high power gyrotrons to the heating and current drive arsenal at DIII-D, required a system upgrade for control of fully steerable ECH Launchers. Each launcher contains two pointing mirrors with two degrees of mechanical freedom. The two flavors of motion are called facet and tilt. Therefore up to four channels of motion per launcher need to be controlled. The system utilizes absolute encoders to indicate mirror position and therefore direction of the microwave beam. The launcher movement is primarily controlled by PLC, but future iterations of design, may require this control to be accomplished by a CPU on fast bus such as Compact PCI. This will be necessary to accomplish real time position control. Safety of equipment and personnel is of primary importance when controlling a system of moving parts. Therefore multiple interlocks and fault status enunciators have been implemented. This paper addresses the design of a Multiple ECH Launcher Control System, and characterizes the flexibility needed to upgrade to a real time position control system in the future

Study on Design of Control Module and Fuzzy Control System

International Nuclear Information System (INIS)

Lee, Chang Kyu; Sohn, Chang Ho; Kim, Jung Seon; Kim, Min Kyu

2005-01-01

Performance of control unit is improved by introduction of fuzzy control theory and compensation for input of control unit as FLC(Fuzzy Logic Controller). Here, FLC drives thermal control system by linguistic rule-base. Hence, In case of using compensative PID control unit, it doesn't need to revise or compensate for PID control unit. Consequently, this study shows proof that control system which implements H/W module and then uses fuzzy algorism in this system is stable and has reliable performance

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

International Nuclear Information System (INIS)

Randle, D.C.

2000-01-01

The primary purpose of this document is to develop a preliminary high-level functional and physical control system architecture for the potential repository at Yucca Mountain. This document outlines an overall control system concept that encompasses and integrates the many diverse process and communication systems being developed for the subsurface repository design. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The Subsurface Repository Integrated Control System design will be composed of a series of diverse process systems and communication networks. The subsurface repository design contains many systems related to instrumentation and control (I andC) for both repository development and waste emplacement operations. These systems include waste emplacement, waste retrieval, ventilation, radiological and air monitoring, rail transportation, construction development, utility systems (electrical, lighting, water, compressed air, etc.), fire protection, backfill emplacement, and performance confirmation. Each of these systems involves some level of I andC and will typically be integrated over a data communications network throughout the subsurface facility. The subsurface I andC systems will also interface with multiple surface-based systems such as site operations, rail transportation, security and safeguards, and electrical/piped utilities. In addition to the I andC systems, the subsurface repository design also contains systems related to voice and video communications. The components for each of these systems will be distributed and linked over voice and video communication networks throughout the subsurface facility. The scope and primary objectives of this design analysis are to: (1) Identify preliminary system-level functions and interfaces (Section 6.2). (2) Examine the overall system complexity and determine how and on what levels the engineered process systems will be monitored

The cryogenic control system of EAST

International Nuclear Information System (INIS)

Zhuang, M.; Hu, L.B.; Zhow, Z.W.; Xia, G.H.

2012-01-01

Highlights: ► A reliable and flexible duplex control system is required for cryogenic system. ► The cryogenic control system is based on Delta-V DCS. ► It has been proved to be an effective way to control cryogenic process. ► It will provide useful experience and inspiration for the development in the cryogenic control engineering. - Abstract: A large scale helium cryogenic system is one of the key components for the EAST tokamak device for the cooling of PF and TF coils, structures, thermal shields, buslines, current leads and cryopumps. Since the cooling scheme of the EAST cryogenic system is fairly complicated, a reliable and flexible control system is required for cryogenic system. The cryogenic control system is based on DeltaV DCS which is the process control software developed by Emerson Company. The EAST cryogenic system has been in operation for four years and has been proved to be safe, stable and energy saving by the past 7 experiments. This paper describes the redundant control network, hardware configuration, software structure, auxiliary system and the new development in the future.

Computer control system of TRISTAN

International Nuclear Information System (INIS)

Kurokawa, Shin-ichi; Shinomoto, Manabu; Kurihara, Michio; Sakai, Hiroshi.

1984-01-01

For the operation of a large accelerator, it is necessary to connect an enormous quantity of electro-magnets, power sources, vacuum equipment, high frequency accelerator and so on and to control them harmoniously. For the purpose, a number of computers are adopted, and connected with a network, in this way, a large computer system for laboratory automation which integrates and controls the whole system is constructed. As a distributed system of large scale, the functions such as electro-magnet control, file processing and operation control are assigned to respective computers, and the total control is made feasible by network connection, at the same time, as the interface with controlled equipment, the CAMAC (computer-aided measurement and control) is adopted to ensure the flexibility and the possibility of expansion of the system. Moreover, the language ''NODAL'' having network support function was developed so as to easily make software without considering the composition of more complex distributed system. The accelerator in the TRISTAN project is composed of an electron linear accelerator, an accumulation ring of 6 GeV and a main ring of 30 GeV. Two ring type accelerators must be synchronously operated as one body, and are controlled with one computer system. The hardware and software are outlined. (Kako, I.)

The integration of two control systems

International Nuclear Information System (INIS)

Bickley, M.; White, K.

1995-01-01

During the past year the Continuous Electron Beam Accelerator Facility (CEBAF) has installed a new machine control system, based on the Experimental Physics and Industrial Control System (EPICS). The migration from CEBAF's old control system, Thaumaturgic Automated Control Logic (TACL), had to be done concurrently with commissioning of the CEBAF accelerator. The smooth transition to EPICS was made possible by the similarity of the control systems' topological design and network communication protocol. Both systems have operator display computer nodes which are decoupled from the data acquisition and control nodes. The communication between display and control nodes of both control systems is based on making named requests for data, with data being passed on change of value. Due to TACL's use of a central communications process, it was possible to integrate both control systems' network communications in that process. This in turn meant that CEBAF did not require changes to any other software in order to support network communication between TACL and EPICS. CEBAF implemented the machine's control under EPICS in an evolutionary, controlled manner. 4 refs., 3 figs

Supervisory Control and Diagnostics System Distributed Operating System

International Nuclear Information System (INIS)

McGoldrick, P.R.

1979-01-01

This paper contains a description of the Supervisory Control and Diagnostics System (SCDS) Distributed Operating System. The SCDS consists of nine 32-bit minicomputers with shared memory. The system's main purpose is to control a large Mirror Fusion Test Facility

Pressure control of hydraulic servo system using proportional control valve

International Nuclear Information System (INIS)

Yang, Kyong Uk; Oh, In Ho; Lee, Ill Yeong

1999-01-01

The purpose of this study is to develop a control scheme for the hydraulic servo system which can rapidly control the pressure in a hydraulic cylinder with very short stroke. Compared with the negligible stroke of the cylinder in the system, the flow gain of the proportional pressure control valve constituting the hydraulic servo system is relatively large and the time delay on the response of the valve is quite long. Therefore, the pressure control system, in this study tends to get unstable during operations. Considering the above mentioned characteristics of the system, a two-degree-of-freedom control scheme, composed of the I-PDD 2 ... feedback compensator and the feedforward controller, is proposed. The reference model scheme is used in deciding the parameters of the controllers. The validity of the proposed control scheme is confirmed through the experiments

Internal control system

OpenAIRE

Pavésková, Ivana

2014-01-01

Dissertation focuse on the internal control system in the enterprises, aims to map the control system by focusing on the purchasing department. I focused on the purchasing process, because with an increasing trends of outsourcing services and the increasing interconnectedness of enterprises increases the risk of fraud currently in the purchasing process. To the research was selected the sample of companies from the banking and non-banking environment, to which were sent a questionnaire focusi...

Safety-related control air systems

International Nuclear Information System (INIS)

Anon.

1977-01-01

This Standard applies to those portions of the control air system that furnish air required to support, control, or operate systems or portions of systems that are safety related in nuclear power plants. This Standard relates only to the air supply system(s) for safety-related air operated devices and does not apply to the safety-related air operated device or to air operated actuators for such devices. The objectives of this Standard are to provide (1) minimum system design requirements for equipment, piping, instruments, controls, and wiring that constitute the air supply system; and (2) the system and component testing and maintenance requirements

Control integral systems; Sistemas integrales de control

Energy Technology Data Exchange (ETDEWEB)

Burgos, Estrella [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1999-12-31

Almost two third of the electric power generation in Mexico are obtained from hydrocarbons, for that reasons Comision Federal de Electricidad (CFE) dedicated special commitment in modernizing the operation of fossil fuel central stations. In attaining this objective the control systems play a fundamental roll, from them depend a good share of the reliability and the efficiency of the electric power generation process, as well as the extension of the equipment useful life. Since 1984 the Instituto de Investigaciones Electricas (IIE) has been working, upon the request of CFE, on the development of digital control systems. To date it has designed and implemented a logic control system for gas burners, which controls 32 burners of the Unit 4 boiler of the Generation Central of Valle de Mexico and two systems for distributed control for two combined cycle central stations, which are: Dos Bocas, Veracruz Combined cycle central, and Gomez Palacio, Durango combined cycle central. With these two developments the IIE enters the World tendency of implementing distributed control systems for the fossil fuel power central update [Espanol] Casi las dos terceras partes de la generacion electrica en Mexico se obtienen a partir de hidrocarburos, es por eso que la Comision Federal de Electricidad (CFE) puso especial empeno en modernizar la operacion de las centrales termoelectricas de combustibles fosiles. En el logro de este objetivo los sistemas de control desempenan un papel fundamental, de ellos depende una buena parte la confiabilidad y la eficiencia en el proceso de generacion de energia electrica, asi como la prolongacion de la vida util de los equipos. Desde 1984 el Instituto de Investigaciones Electricas (IIE) ha trabajado, a solicitud de la CFE, en el desarrollo de sistemas digitales de control. A la fecha se han disenado e implantado un sistema de control logico de quemadores de gas, el cual controla 32 quemadores de la caldera de la unidad 4 de la central de generacion

Control integral systems; Sistemas integrales de control

Energy Technology Data Exchange (ETDEWEB)

Burgos, Estrella [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

1998-12-31

Almost two third of the electric power generation in Mexico are obtained from hydrocarbons, for that reasons Comision Federal de Electricidad (CFE) dedicated special commitment in modernizing the operation of fossil fuel central stations. In attaining this objective the control systems play a fundamental roll, from them depend a good share of the reliability and the efficiency of the electric power generation process, as well as the extension of the equipment useful life. Since 1984 the Instituto de Investigaciones Electricas (IIE) has been working, upon the request of CFE, on the development of digital control systems. To date it has designed and implemented a logic control system for gas burners, which controls 32 burners of the Unit 4 boiler of the Generation Central of Valle de Mexico and two systems for distributed control for two combined cycle central stations, which are: Dos Bocas, Veracruz Combined cycle central, and Gomez Palacio, Durango combined cycle central. With these two developments the IIE enters the World tendency of implementing distributed control systems for the fossil fuel power central update [Espanol] Casi las dos terceras partes de la generacion electrica en Mexico se obtienen a partir de hidrocarburos, es por eso que la Comision Federal de Electricidad (CFE) puso especial empeno en modernizar la operacion de las centrales termoelectricas de combustibles fosiles. En el logro de este objetivo los sistemas de control desempenan un papel fundamental, de ellos depende una buena parte la confiabilidad y la eficiencia en el proceso de generacion de energia electrica, asi como la prolongacion de la vida util de los equipos. Desde 1984 el Instituto de Investigaciones Electricas (IIE) ha trabajado, a solicitud de la CFE, en el desarrollo de sistemas digitales de control. A la fecha se han disenado e implantado un sistema de control logico de quemadores de gas, el cual controla 32 quemadores de la caldera de la unidad 4 de la central de generacion

Diagnostic, reliablility and control systems

CERN Document Server

Leondes

2014-01-01

1. Explicit-Model-Based Fault Detection Method in Industrial Plants 2. Soft Sensor: An Effective Approach to Improve Control 3. Techniques in Soft Computing and Their Utilization in Mechatronic Products 4. Techniques in the Control of Interconnected Plants 5. A Mechatronic Systems Approach to Controlling Robotic Systems with Actuator Dynamics 6. Process and Control Design for Fast Coordinate Measuring Machines 7. Techniques in the Stability of Mechatronic Systems with Sensor or Actuator Failure.

Prevalence and factors associated with vitamin A deficiency in children and adolescents

Directory of Open Access Journals (Sweden)

Rita de Cássia Ribeiro-Silva

2014-09-01

Full Text Available Objective: To identify the prevalence and factors associated with vitamin A deficiency (VAD in children and adolescents. Methods: This was a cross-sectional study involving 546 schoolchildren, aged between 7 and 14 years, of both genders, enrolled in public elementary schools. Blood was collected for measurement of serum retinol. The retinol concentration in the samples was determined by high performance liquid chromatography (HPLC. Data were collected on anthropometrics, dietary, demographic, and socioeconomic factors. Polytomous logistic regression was used to evaluate the associations of interest. Results: Approximately 27.5% of the students had retinol values < 30 μg/dL. The multivariate analysis showed, after the appropriate adjustments, a positive and statistically significant association of moderate/severe VAD (OR = 2.19; 95% CI 1.17 to 4.10 and marginal VAD (OR = 2.34; 95% CI 1.47 to 3.73 with age < 10 years. There was also association of VAD moderate/severe (OR = 2.01; 95% CI 1.01 to 5.05 and borderline VAD (OR = 2.14; 95% CI: 1.08 to 4.21 with the anthropometric status of underweight. Lower intake of retinol was detected among those with severe VAD. Conclusion: VAD is a health concern among children and adolescents. Lower weight and younger schoolchildren had greater vulnerability to VAD.

High pulmonary vascular resistance in addition to low right ventricular stroke work index effectively predicts biventricular assist device requirement.

Science.gov (United States)

Imamura, Teruhiko; Kinugawa, Koichiro; Kinoshita, Osamu; Nawata, Kan; Ono, Minoru

2016-03-01

Although the right ventricular stroke work index (RVSWI) is a good index for RV function, a low RVSWI is not necessarily an indicator for the need for a right ventricular assist device at the time of left VAD implantation. We here aimed to determine a more precise indicator for the need for a biventricular assist device (BiVAD). In total, 116 patients (mean age, 38 ± 14 years), who underwent hemodynamic assessments preoperatively including 12 BiVAD patients, and had been followed at our institute from 2003 to 2015, were included. Multivariate logistic regression analysis indicated that RVSWI and pulmonary vascular resistance (PVR) were independent predictors of BiVAD requirement (P 5 g/m, PVR 5, PVR > 3.7), (3) RV failure (RVSWI 3.7), and examined. Most of the patients in Group 4 (75 %), with acutely depressed hemodynamics and inflammatory responses in the myocardium, required BiVAD. Overall, patients with BiVAD had a worse survival rate as compared with those with LVAD alone. In conclusion, high PVR in addition to low RVSWI effectively predicts BiVAD requirement.

Magnetic spectrometer control system

International Nuclear Information System (INIS)

Lecca, L.A.; Di Paolo, Hugo; Fernandez Niello, Jorge O.; Marti, Guillermo V; Pacheco, Alberto J.; Ramirez, Marcelo

2003-01-01

The design and implementation of a new computerized control system for the several devices of the magnetic spectrometer at TANDAR Laboratory is described. This system, as a main difference from the preexisting one, is compatible with almost any operating systems of wide spread use available in PC. This allows on-line measurement and control of all signals from any terminal of a computer network. (author)

Software control and system configuration management: A systems-wide approach

Science.gov (United States)

Petersen, K. L.; Flores, C., Jr.

1984-01-01

A comprehensive software control and system configuration management process for flight-crucial digital control systems of advanced aircraft has been developed and refined to insure efficient flight system development and safe flight operations. Because of the highly complex interactions among the hardware, software, and system elements of state-of-the-art digital flight control system designs, a systems-wide approach to configuration control and management has been used. Specific procedures are implemented to govern discrepancy reporting and reconciliation, software and hardware change control, systems verification and validation testing, and formal documentation requirements. An active and knowledgeable configuration control board reviews and approves all flight system configuration modifications and revalidation tests. This flexible process has proved effective during the development and flight testing of several research aircraft and remotely piloted research vehicles with digital flight control systems that ranged from relatively simple to highly complex, integrated mechanizations.

PEP instrumentation and control system

Energy Technology Data Exchange (ETDEWEB)

Melen, R.

1980-06-01

This paper describes the operating characteristics of the primary components that form the PEP Instrumentation and Control System. Descriptions are provided for the computer control system, beam monitors, and other support systems.

PEP instrumentation and control system

International Nuclear Information System (INIS)

Melen, R.

1980-06-01

This paper describes the operating characteristics of the primary components that form the PEP Instrumentation and Control System. Descriptions are provided for the computer control system, beam monitors, and other support systems

A metamorphic controller for plant control system design

Directory of Open Access Journals (Sweden)

Tomasz Klopot

2016-07-01

Full Text Available One of the major problems in the design of industrial control systems is the selection and parameterization of the control algorithm. In practice, the most common solution is the PI (proportional-integral controller, which is simple to implement, but is not always the best control strategy. The use of more advanced controllers may result in a better efficiency of the control system. However, the implementation of advanced control algorithms is more time-consuming and requires specialized knowledge from control engineers. To overcome these problems and to support control engineers at the controller design stage, the paper describes a tool, i.e., a metamorphic controller with extended functionality, for selection and implementation of the most suitable control algorithm. In comparison to existing solutions, the main advantage of the metamorphic controller is its possibility of changing the control algorithm. In turn, the candidate algorithms can be tested through simulations and the total time needed to perform all simulations can be less than a few minutes, which is less than or comparable to the design time in the concurrent design approach. Moreover, the use of well-known tuning procedures, makes the system easy to understand and operate even by inexperienced control engineers. The application was implemented in the real industrial programmable logic controller (PLC and tested with linear and nonlinear virtual plants. The obtained simulation results confirm that the change of the control algorithm allows the control objectives to be achieved at lower costs and in less time.

Optimal control of inverted pendulum system using PID controller, LQR and MPC

Science.gov (United States)

Varghese, Elisa Sara; Vincent, Anju K.; Bagyaveereswaran, V.

2017-11-01

Inverted pendulum is a highly nonlinear system. Here we propose an optimal control technique for the control of an inverted Pendulum - cart system. The system is modeled, linearized and controlled. Here, the control objective is to control the system such that when the cart reaches a desired position the inverted pendulum stabilizes in the upright position. Initially PID controller is used to control the system. Later, Linear Quadratic Regulator (LQR) a well-known optimal control technique which makes use of the states of the dynamical system and control input to frame the optimal control decision is used. Various combinations of both PID and LQR controllers are implemented. To validate the robustness of the controller, the system is simulated with and without disturbance. Finally the system is also controlled using Model Predictive controller (MPC). MPC has well predictive ability to calculate future events and implement necessary control actions. The performance of the system is compared and analyzed.

Implementation of the DIAC control system

Energy Technology Data Exchange (ETDEWEB)

Chang, Dae-Sik; Jang, Doh-Yun; Jin, Jeong-Tae; Oh, Byung-Hoon [KAERI, Daejeon (Korea, Republic of)

2015-05-15

DIAC (Daejeon Ion Accelerator Complex) system was developed, and operated at JAEA of Japan by KEK team with a name of TRIAC (Tokai Radioactive Ion Accelerator Complex) during 2004 to 2010. The TRIAC control system was based on LabView and had two independent control units for ion source and accelerator. To be an efficient system, it is necessary to have an integrated control capability. And the control software, which had implemented by using LabView at TRIAC, will be changed with EPICS in order to give an effective beam service to the users. In this presentation, the old TRIAC control system is described, and a new control system for DIAC is discussed. The control system of DIAC is based on TRIAC. But it is gradually improved performance using EPICS toolkits and changing some digital interface hardware of it. Details of the control system will be demonstrated during the conference.

Synchrotron control system of the HIMAC

International Nuclear Information System (INIS)

Takada, E.; Sato, K.; Itano, A.

1994-01-01

A structural design synopsis and the present status of the HIMAC synchrotron control system are described. The control system comprises of Timing System, (ring magnet) Power-supply Controller, Programmable Logic Controller, Static Var Compensator controller, Monitor Controller, RF control computer, Beam Transport control computer and the synchrotron main computer (denoted as CS, hereafter) that forms a local area cluster with man-machine interfacing computers, and communicates with HIMAC supervisor computer. (author)

Dynamitron control systems

International Nuclear Information System (INIS)

Lisanti, Thomas F.

2005-01-01

The Dynamitron control system utilizes the latest personal computer technology in control circuitry and components. Both the DPC-2000 and newer Millennium series of control systems make use of their modular architecture in both software and hardware to keep up with customer and engineering demands. This also allows the main structure of the software to remain constant for the user while software drivers are easily changed as hardware demands are modified and improved. The system is presented as four units; the Remote I/O (Input/Output), Local Analog and Digital I/O, Operator Interface and the Main Computer. The operator is provided with a selection of many informative screen displays. The control program handles all graphic screen displays and the updating of these screens directly; it does not communicate to a display terminal. This adds to the quick response and excellent operator feedback received while operating the accelerator. The CPU also has the ability to store and record all process variable setpoints for each product that will be treated. All process parameters are printed to a report at regular intervals during a process run for record keeping

Automatic control system at the ''Loviisa'' NPP

International Nuclear Information System (INIS)

Kukhtevich, I.V.; Mal'tsev, B.K.; Sergievskaya, E.N.

1980-01-01

Automatic control system of the Loviisa-1 NPP (Finland) is described. According to operation conditions of Finland power system the Loviisa-1 NPP must operate in the mode of week and day control of loading schedule and participate in current control of power system frequency and capacity. With provision for these requirements NPP is equipped with the all-regime system for automatic control functioning during reactor start-up, shut-down, in normal and transient regimes and in emergency situations. The automatic control system includes: a data subsystem, an automatic control subsystem, a discrete control subsystem including remote, a subsystem for reactor control and protection and overall station system of protections: control and dosimetry inside the reactor. Structures of a data-computer complex, discrete control subsystems, reactor control and protection systems, neutron flux control system, inside-reactor control system, station protection system and system for control of fuel element tightness are presented in short. Two-year experience of the NPP operation confirmed advisability of the chosen volume of automatization. The Loviisa-1 NPP operates successfully in the mode of the week and day control of supervisor schedule and current control of frequency (short-term control)

About development of automation control systems

Science.gov (United States)

Myshlyaev, L. P.; Wenger, K. G.; Ivushkin, K. A.; Makarov, V. N.

2018-05-01

The shortcomings of approaches to the development of modern control automation systems and ways of their improvement are given: the correct formation of objects for study and optimization; a joint synthesis of control objects and control systems, an increase in the structural diversity of the elements of control systems. Diagrams of control systems with purposefully variable structure of their elements are presented. Structures of control algorithms for an object with a purposefully variable structure are given.

Control of complex systems

CERN Document Server

Albertos, Pedro; Blanke, Mogens; Isidori, Alberto; Schaufelberger, Walter; Sanz, Ricardo

2001-01-01

The world of artificial systems is reaching complexity levels that es­ cape human understanding. Surface traffic, electricity distribution, air­ planes, mobile communications, etc. , are examples that demonstrate that we are running into problems that are beyond classical scientific or engi­ neering knowledge. There is an ongoing world-wide effort to understand these systems and develop models that can capture its behavior. The reason for this work is clear, if our lack of understanding deepens, we will lose our capability to control these systems and make they behave as we want. Researchers from many different fields are trying to understand and develop theories for complex man-made systems. This book presents re­ search from the perspective of control and systems theory. The book has grown out of activities in the research program Control of Complex Systems (COSY). The program has been sponsored by the Eu­ ropean Science Foundation (ESF) which for 25 years has been one of the leading players in stimula...

Development of similarity theory for control systems

Science.gov (United States)

Myshlyaev, L. P.; Evtushenko, V. F.; Ivushkin, K. A.; Makarov, G. V.

2018-05-01

The area of effective application of the traditional similarity theory and the need necessity of its development for systems are discussed. The main statements underlying the similarity theory of control systems are given. The conditions for the similarity of control systems and the need for similarity control control are formulated. Methods and algorithms for estimating and similarity control of control systems and the results of research of control systems based on their similarity are presented. The similarity control of systems includes the current evaluation of the degree of similarity of control systems and the development of actions controlling similarity, and the corresponding targeted change in the state of any element of control systems.

The cryogenic control system of BEPCⅡ

Institute of Scientific and Technical Information of China (English)

LI Gang; WANG Ke-Xiang; ZHAO Ji-Jiu; YUE Ke-Juan; DAI Ming-Sui; HUANG Yi-Ling; JIANG Bo

2008-01-01

A superconducting cryogenic system has been designed and deployed in the Beijing Electron-Positron Collider Upgrade Project(BEPCⅡ).The system consists of a Siemens PLC(ST-PLC,Programmable Logic Controller)for the compressor control,an Allen Bradley(AB)PLC for the cryogenic equipments,and the Experimental Physics and Industrial Control System(EPICS)that integrates the PLCs.The system fully automates the superconducting cryogenic control with process control,PID(Proportional-Integral-Differential)control loops,real-time data access and data storage,alarm handler and human machine interface.It is capable of automatic recovery as well.This paper describes the BEPCⅡ cryogenic control system,data communication between ST-PLC and EPICS Input/Output Controllers(IOCs),and the integration of the flow control,the low level interlock,the AB-PLC,and EPICS.

System Identification, Environmental Modelling, and Control System Design

CERN Document Server

Garnier, Hugues

2012-01-01

System Identification, Environmetric Modelling, and Control Systems Design is dedicated to Professor Peter Young on the occasion of his seventieth birthday. Professor Young has been a pioneer in systems and control, and over the past 45 years he has influenced many developments in this field. This volume is comprised of a collection of contributions by leading experts in system identification, time-series analysis, environmetric modelling and control system design – modern research in topics that reflect important areas of interest in Professor Young’s research career. Recent theoretical developments in and relevant applications of these areas are explored treating the various subjects broadly and in depth. The authoritative and up-to-date research presented here will be of interest to academic researcher in control and disciplines related to environmental research, particularly those to with water systems. The tutorial style in which many of the contributions are composed also makes the book suitable as ...

Flight control actuation system

Science.gov (United States)

Wingett, Paul T. (Inventor); Gaines, Louie T. (Inventor); Evans, Paul S. (Inventor); Kern, James I. (Inventor)

2006-01-01

A flight control actuation system comprises a controller, electromechanical actuator and a pneumatic actuator. During normal operation, only the electromechanical actuator is needed to operate a flight control surface. When the electromechanical actuator load level exceeds 40 amps positive, the controller activates the pneumatic actuator to offset electromechanical actuator loads to assist the manipulation of flight control surfaces. The assistance from the pneumatic load assist actuator enables the use of an electromechanical actuator that is smaller in size and mass, requires less power, needs less cooling processes, achieves high output forces and adapts to electrical current variations. The flight control actuation system is adapted for aircraft, spacecraft, missiles, and other flight vehicles, especially flight vehicles that are large in size and travel at high velocities.

Control of self-organizing nonlinear systems

CERN Document Server

Klapp, Sabine; Hövel, Philipp

2016-01-01

The book summarizes the state-of-the-art of research on control of self-organizing nonlinear systems with contributions from leading international experts in the field. The first focus concerns recent methodological developments including control of networks and of noisy and time-delayed systems. As a second focus, the book features emerging concepts of application including control of quantum systems, soft condensed matter, and biological systems. Special topics reflecting the active research in the field are the analysis and control of chimera states in classical networks and in quantum systems, the mathematical treatment of multiscale systems, the control of colloidal and quantum transport, the control of epidemics and of neural network dynamics.

Embedded Sensors and Controls to Improve Component Performance and Reliability - System Dynamics Modeling and Control System Design

Energy Technology Data Exchange (ETDEWEB)

Melin, Alexander M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kisner, Roger A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Fugate, David L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2013-10-01

This report documents the current status of the modeling, control design, and embedded control research for the magnetic bearing canned rotor pump being used as a demonstration platform for deeply integrating instrumentation and controls (I{\\&}C) into nuclear power plant components. This pump is a highly inter-connected thermo/electro/mechanical system that requires an active control system to operate. Magnetic bearings are inherently unstable system and without active, moment by moment control, the rotor would contact fixed surfaces in the pump causing physical damage. This report details the modeling of the pump rotordynamics, fluid forces, electromagnetic properties of the protective cans, active magnetic bearings, power electronics, and interactions between different dynamical models. The system stability of the unforced and controlled rotor are investigated analytically. Additionally, controllers are designed using proportional derivative (PD) control, proportional integral derivative (PID) control, voltage control, and linear quadratic regulator (LQR) control. Finally, a design optimization problem that joins the electrical, mechanical, magnetic, and control system design into one problem to balance the opposing needs of various design criteria using the embedded system approach is presented.

Specification of EDITH motion control system

International Nuclear Information System (INIS)

Breitwieser, H.; Frank, A.; Holler, E.; Suess, U.; Leinemann, K.

1990-09-01

EDITH is an experimental device for in vessel handling at NET/ITER. The purpose of EDITH is: Testing of ABS (articulated boom system) components; testing and validation of remote handling procedures; testing and validation of ABS end-effectors; testing of ABS control system features and verification of control system concepts. This document, after describing the environment in which the control system is to operate, specifies architecture and functionality to be implemented by the EDITH motion control system software, thereby taking full reference to the control system specification for TARM, which was decided to be the base for the implementation. (orig.) [de

IMPULSE CONTROL HYBRID ELECTRICAL SYSTEM

Directory of Open Access Journals (Sweden)

A. A. Lobaty

2016-01-01

Full Text Available This paper extends the recently introduced approach for modeling and solving the optimal control problem of fixedswitched mode DC-DC power converter. DCDC converters are a class of electric power circuits that used extensively in regulated DC power supplies, DC motor drives of different types, in Photovoltaic Station energy conversion and other applications due to its advantageous features in terms of size, weight and reliable performance. The main problem in controlling this type converters is in their hybrid nature as the switched circuit topology entails different modes of operation, each of it with its own associated linear continuous-time dynamics.This paper analyses the modeling and controller synthesis of the fixed-frequency buck DC-DC converter, in which the transistor switch is operated by a pulse sequence with constant frequency. In this case the regulation of the DC component of the output voltage is via the duty cycle. The optimization of the control system is based on the formation of the control signal at the output.It is proposed to solve the problem of optimal control of a hybrid system based on the formation of the control signal at the output of the controller, which minimizes a given functional integral quality, which is regarded as a linear quadratic Letov-Kalman functional. Search method of optimal control depends on the type of mathematical model of control object. In this case, we consider a linear deterministic model of the control system, which is common for the majority of hybrid electrical systems. For this formulation of the optimal control problem of search is a problem of analytical design of optimal controller, which has the analytical solution.As an example of the hybrid system is considered a step-down switching DC-DC converter, which is widely used in various electrical systems: as an uninterruptible power supply, battery charger for electric vehicles, the inverter in solar photovoltaic power plants.. A

Control systems under attack?

CERN Document Server

Lüders, Stefan

2005-01-01

The enormous growth of the Internet during the last decade offers new means to share and distribute both information and data. In Industry, this results in a rapprochement of the production facilities, i.e. their Process Control and Automation Systems, and the data warehouses. At CERN, the Internet opens the possibility to monitor and even control (parts of) the LHC and its four experiments remotely from anywhere in the world. However, the adoption of standard IT technologies to Distributed Process Control and Automation Systems exposes inherent vulnerabilities to the world. The Teststand On Control System Security at CERN (TOCSSiC) is dedicated to explore the vulnerabilities of arbitrary Commercial-Of-The-Shelf hardware devices connected to standard Ethernet. As such, TOCSSiC should discover their vulnerabilities, point out areas of lack of security, and address areas of improvement which can then be confidentially communicated to manufacturers. This paper points out risks of accessing the Control and Automa...

Robust tracking control of uncertain Duffing-Holmes control systems

International Nuclear Information System (INIS)

Sun, Y.-J.

2009-01-01

In this paper, the notion of virtual stabilizability for dynamical systems is introduced and the virtual stabilizability of uncertain Duffing-Holmes control systems is investigated. Based on the time-domain approach with differential inequality, a tracking control is proposed such that the states of uncertain Duffing-Holmes control system track the desired trajectories with any pre-specified exponential decay rate and convergence radius. Moreover, we present an algorithm to find such a tracking control. Finally, a numerical example is provided to illustrate the use of the main results.

Control Evaluation Information System Savings

Directory of Open Access Journals (Sweden)

Eddy Sutedjo

2011-05-01

Full Text Available The purpose of this research is to evaluate the control of information system savings in the banking and to identify the weaknesses and problem happened in those saving systems. Research method used are book studies by collecting data and information needed and field studies by interview, observation, questioner, and checklist using COBIT method as a standard to assess the information system control of the company. The expected result about the evaluation result that show in the problem happened and recommendation given as the evaluation report and to give a view about the control done by the company. Conclusion took from this research that this banking company has met standards although some weaknesses still exists in the system.Index Terms - Control Information System, Savings

Model Based Control of Refrigeration Systems

DEFF Research Database (Denmark)

Larsen, Lars Finn Sloth

for automation of these procedures, that is to incorporate some "intelligence" in the control system, this project was started up. The main emphasis of this work has been on model based methods for system optimizing control in supermarket refrigeration systems. The idea of implementing a system optimizing...... control is to let an optimization procedure take over the task of operating the refrigeration system and thereby replace the role of the operator in the traditional control structure. In the context of refrigeration systems, the idea is to divide the optimizing control structure into two parts: A part...... optimizing the steady state operation "set-point optimizing control" and a part optimizing dynamic behaviour of the system "dynamical optimizing control". A novel approach for set-point optimization will be presented. The general idea is to use a prediction of the steady state, for computation of the cost...

The rejuvenation of TRISTAN control system

International Nuclear Information System (INIS)

Mimashi, T.; Urakawa, J.; Kurokawa, S.; Kawamoto, T.; Takeda, S.; Akiyama, A.; Kudoh, K.; Komada, K.; Naitoh, T.

1992-01-01

The current TRISTAN accelerator control system uses CAMAC as a front end electronics, and they are controlled by twenty five Hitachi minicomputer HIDIC 80's which are linked with an N-to-N token ring network. After five years from now, these computers must be replaced. This is because of the life time of control system and we have to cope with the requirements imposed by our future project such as the KEK B-Factory and the main ring photon factory projects. The rejuvenation of this control has to be done under some constraints such as the lack of manpower, limited time and financing. First we review the problems of current control system, then the philosophy of the new generation control system is presented. Finally it is discussed how to move to the new generation control system from the current TRISTAN control system. (author)

Argonne's atlas control system upgrade

International Nuclear Information System (INIS)

Munson, F.; Quock, D.; Chapin, B.; Figueroa, J.

1999-01-01

The ATLAS facility (Argonne Tandem-Linac Accelerator System) is located at the Argonne National Laboratory. The facility is a tool used in nuclear and atomic physics research, which focuses primarily on heavy-ion physics. The accelerator as well as its control system are evolutionary in nature, and consequently, continue to advance. In 1998 the most recent project to upgrade the ATLAS control system was completed. This paper briefly reviews the upgrade, and summarizes the configuration and features of the resulting control system

Distributed control system for the FMIT

International Nuclear Information System (INIS)

Johnson, J.A.; Machen, D.R.; Suyama, R.M.

1979-01-01

The control system for the Fusion Materials Irradiation Test (FMIT) Facility will provide the primary data acquisition, control, and interface components that integrate all of the individual FMIT systems into a functional facility. The control system consists of a distributed computer network, control consoles and instrumentation subsystems. The FMIT Facility will be started, operated and secured from a Central Control Room. All FMIT systems and experimental functions will be monitored from the Central Control Room. The data acquisition and control signals will be handled by a data communications network, which connects dual computers in the Central Control Room to the microcomputers in CAMAC crates near the various subsystems of the facility

Nova control system: goals, architecture, and system design

International Nuclear Information System (INIS)

Suski, G.J.; Duffy, J.M.; Gritton, D.G.; Holloway, F.W.; Krammen, J.R.; Ozarski, R.G.; Severyn, J.R.; Van Arsdall, P.J.

1982-01-01

The control system for the Nova laser must operate reliably in a harsh pulse power environment and satisfy requirements of technical functionality, flexibility, maintainability and operability. It is composed of four fundamental subsystems: Power Conditioning, Alignment, Laser Diagnostics, and Target Diagnostics, together with a fifth, unifying subsystem called Central Controls. The system architecture utilizes a collection of distributed microcomputers, minicomputers, and components interconnected through high speed fiber optic communications systems. The design objectives, development strategy and architecture of the overall control system and each of its four fundamental subsystems are discussed. Specific hardware and software developments in several areas are also covered

Noninteracting control of nonlinear systems based on relaxed control

NARCIS (Netherlands)

Jayawardhana, B.

2010-01-01

In this paper, we propose methodology to solve noninteracting control problem for general nonlinear systems based on the relaxed control technique proposed by Artstein. For a class of nonlinear systems which cannot be stabilized by smooth feedback, a state-feedback relaxed control can be designed to

Modernization of control system using the digital control system; Modernizacion de sistemas de control usando la simulacion como herramiento de ingenieria

Energy Technology Data Exchange (ETDEWEB)

Carrasco, J. A.; Fernandez, L.; Jimenez, A.

2002-07-01

Nowadays, all plant automation tendencies are based on the use of Digital Control System. In big industrial plants the control systems employed are Distributed Control Systems (DCS). The addition of these systems in nuclear power plants,implies an important adaptation process, because most of them were installed using analog control systems. This paper presents the objectives and the first results obtained, in a modernization project, focused in obtaining an engineering platform for making test and analysis of changes prior to their implementation in a nuclear plant. Modernization, Upgrade, DCS, Automation, Simulation, Training. (Author)

The Epicure Control System

International Nuclear Information System (INIS)

Dambik, E.; Kline, D.; West, R.

1993-09-01

The Epicure Control System supports the Fermilab fixed target physics program. The system is distributed across a network of many different types of components. The use of multiple layers on interfaces for communication between logical tasks fits the client-server model. Physical devices are read and controlled using symbolic references entered into a database with an editor utility. The database system consists of a central portion containing all device information and optimized portions distributed among many nodes. Updates to the database are available throughout the system within minutes after being requested

Gain scheduling controller for pitch control of a TRMS system

Science.gov (United States)

Bhagyalakshmi, R.; Rashmi, GP; Jaganatha Pandian, B.

2017-11-01

Gain scheduling is a control technique which is applied for the control of non-linear systems by using a family of linear controllers at different operating points so as to increase the range of operation of the process. The dynamics of any nonlinear system changes with respect to operating points. These operating points are characterized by one or more variables known as scheduling variables. In such cases, we linearize the system at different equilibrium points. Due to the high amount of non-linearities and complexity in the aerodynamic design, modelling of other unmanned aerial vehicles have been replaced here with twin rotor system. The linearized system is then controlled by using PID controllers which are designed with respect to the obtained operating points. Linearizing of the non-linear system, designing and tuning of PID are being implemented using different MATLAB functions.

Vitamin A deficiency and anemia among children 12-71 months old in Honduras

Directory of Open Access Journals (Sweden)

Penelope Nestel

1999-07-01

Full Text Available Vitamin A deficiency (VAD and iron deficiency anemia (IDA have been recognized as public health problems in Honduras for over 30 years. This paper, based on the 1996 National Micro nutrient Survey on 1 678 children 12–71 months of age, presents the results for vitamin A status and anemia prevalence, as well as the level of vitamin A in sugar at the household level. The results showed that 14% of the children were subclinically vitamin A deficient (plasma retinol < 20 µg/dL and 32% were at risk of VAD (plasma retinol 20–30 µg/dL. These data indicate that VAD is a moderate public health problem in Honduras. Logistic regression analysis showed that children 12–23 months old living in areas other than the rural south of the country were at greatest risk of subclinical VAD. Infection, indicated by an elevated alpha-1-acid-glycoprotein level, increased the risk of subclinical VAD more than three-fold. Children from households that obtained water from a river, stream, or lake were at twice the risk of subclinical VAD compared with other children. That same doubled risk was found for children from a household with an outside toilet. VAD can be controlled by fortifying sugar. Retinol levels in sugar at the household level were about 50% of those mandated by Honduran law. There appears to be significant leakage of unfortified sugar into the market. This is particularly true in the rural north, where 33% of samples contained no retinol. Overall, 30% of children were anemic (Hb < 11 g/dL. Logistic regression analysis showed that children whose fathers lived with them but who had not attended at least grade 4 of primary school were at 33% greater risk of being anemic. Infection and being underweight increased the risk of being anemic by 51% and 21%, respectively. Many of the anemic children had not been given iron supplements, suggesting health care providers may not be aware that anemia is widespread among young children and/or know how to diagnose it.

Asynchronous control for networked systems

CERN Document Server

Rubio, Francisco; Bencomo, Sebastián

2015-01-01

This book sheds light on networked control systems; it describes different techniques for asynchronous control, moving away from the periodic actions of classical control, replacing them with state-based decisions and reducing the frequency with which communication between subsystems is required. The text focuses specially on event-based control. Split into two parts, Asynchronous Control for Networked Systems begins by addressing the problems of single-loop networked control systems, laying out various solutions which include two alternative model-based control schemes (anticipatory and predictive) and the use of H2/H∞ robust control to deal with network delays and packet losses. Results on self-triggering and send-on-delta sampling are presented to reduce the need for feedback in the loop. In Part II, the authors present solutions for distributed estimation and control. They deal first with reliable networks and then extend their results to scenarios in which delays and packet losses may occur. The novel ...

Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone

Energy Technology Data Exchange (ETDEWEB)

Haberkorn, Uwe E-mail: uwe_haberkorn@med.uni-heidelberg.de; Kinscherf, Ralf; Krammer, Peter H.; Mier, Walter; Eisenhut, Michael

2001-10-01

The imaging of apoptosis represents an attractive diagnostic goal in the area of tumor therapy, degenerative diseases and organ transplantation. Since caspases play a key role during the early period of the intracellular signal cascade of cells undergoing apoptosis we considered benzyloxycarbonyl-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone [Z-VAD-fmk], a pan-caspase inhibitor, as a potential apoptosis imaging agent. Applying the Tl(TFA){sub 3}/[{sup 131}I]iodide method Z-VAD-fmk was successfully labeled at the benzyloxycarbonyl protecting group. The success of radioiodination, however, depended on the presence of carrier iodide resulting in specific radioactivities of 2.6 GBq/{mu}mol and the formation of a mixture of the 2- and 4-iodophenyl derivative (61%) which could not be separated by HPLC. Uptake measurements were performed with Morris hepatoma cells (MH3924Atk8) which showed expression of the Herpes Simplex Virus thymidine kinase (HSVtk) gene. Apoptosis was induced by treatment of the cells with 25 {mu}M ganciclovir. The TUNEL assay revealed 1.3{+-}0.3 and 23{+-}1.1% apoptotic cells immediately and 24 h after therapy, respectively. A two-fold increase of [{sup 131}I]IZ-VAD-fmk uptake was found at the end of treatment with the HSVtk/suicide system which constantly remained elevated for the following 4 hours. The slow cellular influx and lack of uptake saturation of [{sup 131}I]IZ-VAD-fmk are evidence for simple diffusion as transport mechanism. In addition, the absolute cellular uptake of [{sup 131}I]IZ-VAD-fmk was found to be low. This quality was related to the rather high lipophilicity of [{sup 131}I]IZ-VAD-fmk causing unspecific binding to macromolecules in the medium. Instead of using an inhibitor, synthetic caspase substrates are currently investigated which may accumulate in the apoptotic cell by metabolic trapping thereby enhancing the imaging signal.

The control system

International Nuclear Information System (INIS)

1988-01-01

The present control system has matured both in terms of age and capacity. Thus a new system based on a local area network (LAN) is being developed. A pilot project has been started but, owing to difficulties encountered with the present operating system used with the microprocessors, it has become necessary to reconsider the choice of operating system. A recently-released multi-tasking operating system that runs on the existing hardware has been chosen. 1 fig

Generic device controller for accelerator control systems

International Nuclear Information System (INIS)

Mariotti, R.; Buxton, W.; Frankel, R.; Hoff, L.

1987-01-01

Distributed intelligence for accelerator control systems has become possible as a result of advances in microprocessor technology. A system based on distributed intelligence is inherently versatile, readily expandable, and reduces both information flow across the system and software complexity in each unit

PLC VVVF Elevator Control System

OpenAIRE

Tang, Yujian; Gui, Tianyu

2016-01-01

The aim of the thesis is to introduce the PLC VVVF elevator and its control system. The thesis can be divided into three parts. The first part is about the overview of the lift: the kinds of the lift and the structure of the lift, it shows the knowledge about the components and the operating systems of the lift. The second part is about the PLC control system, it’s about the operations of the lift from the introduction about the hardware and software of the PLC control system. And the thi...

Advances and applications in nonlinear control systems

CERN Document Server

Volos, Christos

2016-01-01

The book reports on the latest advances and applications of nonlinear control systems. It consists of 30 contributed chapters by subject experts who are specialized in the various topics addressed in this book. The special chapters have been brought out in the broad areas of nonlinear control systems such as robotics, nonlinear circuits, power systems, memristors, underwater vehicles, chemical processes, observer design, output regulation, backstepping control, sliding mode control, time-delayed control, variables structure control, robust adaptive control, fuzzy logic control, chaos, hyperchaos, jerk systems, hyperjerk systems, chaos control, chaos synchronization, etc. Special importance was given to chapters offering practical solutions, modeling and novel control methods for the recent research problems in nonlinear control systems. This book will serve as a reference book for graduate students and researchers with a basic knowledge of electrical and control systems engineering. The resulting design proce...

Herbal Medicine for the Treatment of Vascular Dementia: An Overview of Scientific Evidence

Directory of Open Access Journals (Sweden)

Dennis Chang

2016-01-01

Full Text Available Dementia is a leading cause of mental and physical disability. Vascular dementia (VaD is the second most common cause of dementia after Alzheimer’s disease (AD constituting 10–15% of the dementia population. Currently there are no approved pharmaceutical options for VaD and the conventional anti-AD therapies provide only modest, short-term relief of symptoms associated with VaD. Herbal medicines have been used for the management of dementia-like symptoms for centuries and may provide viable therapies for VaD due to their multicomponent and multitarget approach. This review is designed to provide an updated overview on the current status of herbal medicine research, with an emphasis on Chinese herbal medicine, for the treatment of VaD or dementia. A case study is also provided to demonstrate the development process of a novel standardized complex herbal formulation for VaD. The article reveals some preliminary evidence to support the use of single and complex herbal preparations for VaD and dementia. Multiple issues in relation to clinical and preclinical research have been identified and future research directions are discussed.

The pharmacotherapy implications of ventricular assist device in the patient with end-stage heart failure.

Science.gov (United States)

Von Ruden, Serena A S; Murray, Margaret A; Grice, Jennifer L; Proebstle, Amy K; Kopacek, Karen J

2012-04-01

Advances in mechanical circulatory support, such as the use of ventricular assist devices (VADs), have become a means for prolonging survival in end-stage heart failure (HF). VADs decrease the symptoms of HF and improve quality of life by replacing some of the work of a failing heart. They unload the ventricle to provide improved cardiac output and end-organ perfusion, resulting in improvement in cardiorenal syndromes and New York Heart Association functional class rating. VADs are currently used asa bridge to heart transplantation, a bridge to recovery of cardiac function, or as destination therapy. Complications of VAD include bleeding, infections, arrhythmias, multiple organ failure, right ventricular failure, and neurological dysfunction. Patients with VAD have unique pharmacotherapeutic requirements in terms of anticoagulation, appropriate antibiotic selection, and continuation of HF medications. Pharmacists in acute care and community settings are well prepared to care for the patient with VAD. These patients require thorough counseling and follow-up with regard to prevention and treatment of infections, appropriate levels of anticoagulation, and maintenance of fluid balance. A basic understanding of this unique therapy can assist pharmacists in attending to the needs of patients with VAD.

SRS control system upgrade requirements

International Nuclear Information System (INIS)

Hill, L.F.

1998-01-01

This document defines requirements for an upgrade of the Sodium Removal System (SRS) control system. The upgrade is being performed to solve a number of maintainability and operability issues. The upgraded system will provide the same functions, controls and interlocks as the present system, and in addition provide enhanced functionality in areas discussed in this document

Improving industrial process control systems security

CERN Document Server

Epting, U; CERN. Geneva. TS Department

2004-01-01

System providers are today creating process control systems based on remote connectivity using internet technology, effectively exposing these systems to the same threats as corporate computers. It is becoming increasingly difficult and costly to patch/maintain the technical infrastructure monitoring and control systems to remove these vulnerabilities. A strategy including risk assessment, security policy issues, service level agreements between the IT department and the controls engineering groups must be defined. In addition an increased awareness of IT security in the controls system engineering domain is needed. As consequence of these new factors the control system architectures have to take into account security requirements, that often have an impact on both operational aspects as well as on the project and maintenance cost. Manufacturers of industrial control system equipment do however also propose progressively security related solutions that can be used for our active projects. The paper discusses ...

Fuzzy logic for structural system control

Directory of Open Access Journals (Sweden)

Herbert Martins Gomes

Full Text Available This paper provides some information and numerical tests that aims to investigate the use of a Fuzzy Controller applied to control systems. Some advantages are reported regarding the use of this controller, such as the characteristic ease of implementation due to its semantic feature in the statement of the control rules. On the other hand, it is also hypothesized that these systems have a lower performance loss when the system to be controlled is nonlinear or has time varying parameters. Numerical tests are performed using modal LQR optimal control and Fuzzy control of non-collocated systems with full state feedback in a two-dimensional structure. The paper proposes a way of designing a controller that may be a supervisory Fuzzy controller for a traditional controller or even a fuzzy controller independent from the traditional control, consisting on individual mode controllers. Some comments are drawn regarding the performance of these proposals in a number of arrangements.

The Glucose-Insulin Control System

DEFF Research Database (Denmark)

Hallgreen, Christine Erikstrup; Korsgaard, Thomas Vagn; Hansen, RenéNormann N.

2008-01-01

This chapter reviews the glucose-insulin control system. First, classic control theory is described briefly and compared with biological control. The following analysis of the control system falls into two parts: a glucose-sensing part and a glucose-controlling part. The complex metabolic pathways...... are divided into smaller pieces and analyzed via several small biosimulation models that describe events in beta cells, liver, muscle and adipose tissue etc. In the glucose-sensing part, the beta cell are shown to have some characteristics of a classic PID controller, but with nonlinear properties...... control, the analysis shows that the system has many more facets than just keeping the glucose concentration within narrow limits. After glucose enters the cell and is phosphorylated to glucose-6-phosphate, the handling of glucose-6-phosphate is critical for glucose regulation. Also, this handling...

Synthesis of pneumatic controll systems

Directory of Open Access Journals (Sweden)

D. Nowak

2011-04-01

Full Text Available Currently, the basic tool for automating the production processes are the PLCs. However, in many areas application of the pneumaticcontrol systems may be more reasonable. The main factor determining choice of the control technology are costs. In the case of pneumaticsystems, the costs shall be determined by the number of elements used. Therefore, during the design works it is important to choose anappropriate method for the pneumatic control systems synthesis. The article presents the MTS method, which may be used for a discretetechnological processes modeling and PLC programming, as well as for a pneumatic control systems designing. An important element ofthe MTS method is the network of actions, which graphically presents an algorithm of the implemented process. Based on the actionnetwork and operating machine’s functional diagram, the diagram of different states is determinated, which graphically shows changes ofthe control system’s input and output signals. Analysis of the diagram of different states, makes it easy to determine a schematic equation, which shall be the basis for the control system implementation. Advantage of the MTS method is the lack of restrictions on the number of the control system’s input and output signals. The resulting solution is characterized by a minimum number of elements needed to implement the control system.

Standardization of detector control systems

International Nuclear Information System (INIS)

Fukunaga, Chikara

2000-01-01

Current and future detectors for high-energy and/or nuclear physics experiments require highly intelligent detector control systems. In order to reduce resources, the construction of a standardized template for the control systems based on the commercially available superviser control and data acquisition (SCADA) system has been proposed. The possibility of constructing this template is discussed and several key issues for evaluation of SCADA as the basis for such a template are presented. (author)

Superconducting Coil Winding Machine Control System

Energy Technology Data Exchange (ETDEWEB)

Nogiec, J. M. [Fermilab; Kotelnikov, S. [Fermilab; Makulski, A. [Fermilab; Walbridge, D. [Fermilab; Trombly-Freytag, K. [Fermilab

2016-10-05

The Spirex coil winding machine is used at Fermilab to build coils for superconducting magnets. Recently this ma-chine was equipped with a new control system, which al-lows operation from both a computer and a portable remote control unit. This control system is distributed between three layers, implemented on a PC, real-time target, and FPGA, providing respectively HMI, operational logic and direct controls. The system controls motion of all mechan-ical components and regulates the cable tension. Safety is ensured by a failsafe, redundant system.

Tritium system test assembly control system cost estimate

International Nuclear Information System (INIS)

Stutz, R.A.

1979-01-01

The principal objectives of the Tritium Systems Test Assembly (TSTA), which includes the development, demonstration and interfacing of technologies related to the deuterium--tritium fuel cycle for fusion reactor systems, are concisely stated. The various integrated subsystems comprising TSTA and their functions are discussed. Each of the four major subdivisions of TSTA, including the main process system, the environmental and safety systems, supporting systems and the physical plant are briefly discussed. An overview of the Master Data Acquisition and Control System, which will control all functional operation of TSTA, is provided

Anàlisi i tècniques de processat del senyal per a la generació de mapes eòlics

OpenAIRE

Martínez Domingo, Carme

2009-01-01

L'emplaçament del projecte es situa a un parc eòlic marítim, on es vol observar el vent a través del radar VAD, Velocity Azimuth Display, per poder controlar la velocitat de rotació dels aerogeneradors, i poder substituir els actuals anemòmetres. No ens centrarem en el control d'aquest, sinó que l'objectiu principal d'aquest projecte és analitzar el funcionament i processat de dades del VAD. Es proposaran, simularan i estudiaran noves tècniques d'estimació espectral per obtenir una millora im...

Upgrading the ATLAS control system

International Nuclear Information System (INIS)

Munson, F.H.; Ferraretto, M.

1993-01-01

Heavy-ion accelerators are tools used in the research of nuclear and atomic physics. The ATLAS facility at the Argonne National Laboratory is one such tool. The ATLAS control system serves as the primary operator interface to the accelerator. A project to upgrade the control system is presently in progress. Since this is an upgrade project and not a new installation, it was imperative that the development work proceed without interference to normal operations. An additional criteria for the development work was that the writing of additional ''in-house'' software should be kept to a minimum. This paper briefly describes the control system being upgraded, and explains some of the reasons for the decision to upgrade the control system. Design considerations and goals for the new system are described, and the present status of the upgrade is discussed

Slug control system; Sistema de controle de golfadas

Energy Technology Data Exchange (ETDEWEB)

Borges Filho, Alvaro de Miranda; Meira, Marco Antonio Alves de; Vaz, Celio Eduardo Martins [PETROBRAS, Macae, RJ (Brazil). Unidade de Negocios da Bacia de Campos

2004-07-01

Due to the characteristics of flow, gas can separate from oil in the pipelines and risers that link subsea manifolds to production offshore platforms, forming liquid and gas slugs in the production separator. Liquid slugs can cause overflow in the separators. Gas slugs can cause burning in the flare due to the limitation in the turbo-compressors acceleration. In both cases the consequences are loss of production or shut-downs. This paper presents a Slug Control System designed to attenuate severe gas and liquid flow variations. The system consist of a control valve installed in the separator inlet, transmitters, a controller, control algorithm and a monitoring station. This system is operating since October 2003 in a production offshore platform, in Campus Basin, Brazil, with excellent results, reducing the gas burning in 45% without oil production loss. (author)

Control system reliability at Jefferson Lab

International Nuclear Information System (INIS)

White, K.S.; Areti, H.; Garza, O.

1997-01-01

At Thomas Jefferson National Accelerator Facility (Jefferson Lab), the availability of the control system is crucial to the operation of the accelerator for experimental programs. Jefferson Lab's control system, uses 68040 based microprocessors running VxWorks, Unix workstations, and a variety of VME, CAMAC. GPIB, and serial devices. The software consists of control system toolkit software, commercial packages, and over 200 custom and generic applications, some of which are highly complex. The challenge is to keep this highly diverse and still growing system, with over 162,000 control points, operating reliably, while managing changes and upgrades to both the hardware and software. Downtime attributable to the control system includes the time to troubleshoot and repair problems and the time to restore the machine to operation of the scheduled program. This paper describes the availability of the control system during the last year, the heaviest contributors to downtime and the response to problems. Strategies for improving the robustness of the control system am detailed and include changes in hardware, software, procedures and processes. The improvements range from the routine preventive hardware maintenance, to improving their ability to detect, predict and prevent problems. This paper also describes the software tools used to assist in control system troubleshooting, maintenance and failure recovery processes

EMPLACEMENT DRIFT ISOLATION DOOR CONTROL SYSTEM

International Nuclear Information System (INIS)

N.T. Raczka

1998-01-01

The purpose of this analysis is to review and refine key design concepts related to the control system presently under consideration for remotely operating the emplacement drift isolation doors at the potential subsurface nuclear waste repository at Yucca Mountain. This analysis will discuss the key design concepts of the control system that may be utilized for remotely monitoring, opening, and closing the emplacement drift isolation doors. The scope and primary objectives of this analysis are to: (1) Discuss the purpose and function of the isolation doors (Presented in Section 7.1). (2) Review the construction of the isolation door and other physical characteristics of the doors that the control system will interface with (Presented in Section 7.2). (3) Discuss monitoring and controlling the operation of the isolation doors with a digital control system (either a Programmable Logic Controller (PLC) system or a Distributed Control System (DCS)) (Presented in Section 7.3). (4) Discuss how all isolation doors can be monitored and controlled from a subsurface central control center (Presented in Section 7.4). This analysis will focus on the development of input/output (I/O) counts including the types of I/O, redundancy and fault tolerance considerations, and processor requirements for the isolation door control system. Attention will be placed on operability, maintainability, and reliability issues for the system operating in the subsurface environment with exposure to high temperatures and radiation

Highly reliable electro-hydraulic control system

International Nuclear Information System (INIS)

Mande, Morima; Hiyama, Hiroshi; Takahashi, Makoto

1984-01-01

The unscheduled shutdown of nuclear power stations disturbs power system, and exerts large influence on power generation cost due to the lowering of capacity ratio; therefore, high reliability is required for the control system of nuclear power stations. Toshiba Corp. has exerted effort to improve the reliability of the control system of power stations, and in this report, the electro-hydraulic control system for the turbines of nuclear power stations is described. The main functions of the electro-hydraulic control system are the control of main steam pressure with steam regulation valves and turbine bypass valves, the control of turbine speed and load, the prevention of turbine overspeed, the protection of turbines and so on. The system is composed of pressure sensors and a speed sensor, the control board containing the electronic circuits for control computation and protective sequence, the oil cylinders, servo valves and opening detectors of the valves for control, a high pressure oil hydraulic machine and piping, the operating panel and so on. The main features are the adoption of tripling intermediate value selection method, the multiplying of protection sensors and the adoption of 2 out of 3 trip logic, the multiplying of power sources, the improvement of the reliability of electronic circuit hardware and oil hydraulic system. (Kako, I.)

PSR control system

International Nuclear Information System (INIS)

Clout, P.N.; Conley, A.P.; Bair, S.S.; Fuka, M.A.; Sandford, E.L.; Lander, R.F.; Wells, F.D.

1985-01-01

The control system for the Proton Storage Ring at Los Alamos has been essentially completed. Modifications are being applied that are required in the light of machine physics and operating experience. The present design of the system is described and future planned modifications are indicated

JT-60 plasma control system

International Nuclear Information System (INIS)

Kurihara, K.

1988-01-01

JT-60 plasma control can be performed by the supervisory controller, the measurement system and actuators such as the poloidal field coil power supplies, gas injectors, neutral beam injection (NBI) heating system and radio frequency (RF) heating system. One of the most important characteristics of this system is a perfect digital control one composed of mini-computers, fast array processors and CAMAC modules, and it has large flexibility and few troubles to adjust the system. This system started to be operated in April 1985, after the six-year-long design, construction and testing, and have been operated and improved many times for two years. In this paper, the final system specification and its performance are presented aiming at the technological aspect of hardware and software. In addition, and experienced troubles are also presented. (author)

Ideas on a generic control systems based on the experience on the 4 LEP experiments control system

International Nuclear Information System (INIS)

Barillere, R.; Le Goff, J.M.; Milcent, H.; Stampfli, R.

1992-01-01

Most of the large slow control systems in the LEP collider experiments are distributed heterogeneous and multi-standard. But in spite of the appearances, they have a lot in common. From our direct experience on the L-3 slow control system and from the informations we obtained on the 3 other LEP experiments control systems we have come to the conclusion that it should be possible to build a Generic Control Package from which any control system could be derived. This software package is entirely based on relational databases and is intended to provide all the necessary tools to build a modular, coherent, easy to update and to maintain control system. Among other things this package should include user friendly interfaces, expert systems, and powerful graphic monitoring and control tools. This paper will present our general ideas about the realization of such a package. (author)

Control system technology for particle accelerators

International Nuclear Information System (INIS)

Tsumura, Yoshihiko; Matsuo, Keiichi; Maruyama, Takayuki.

1995-01-01

Control systems for particle accelerators are being designed around open-architecture systems, which allows easy upgrading, high-speed networks and high-speed processors. Mitsubishi Electric is applying realtime Unix operating systems, fiber-distributed data interface (FDDI), shared memory networks and remote I/O systems to achieve these objectives. In the area of vacuum control systems, which requires large-scale sequence control, the corporation is employing general-purpose programmable logic controllers (PLCs) to achieve cost-effective design. Software for these applications is designed around a library of application program interfaces (APIs) that give users direct access to key system functions. (author)

Robust lyapunov controller for uncertain systems

KAUST Repository

Laleg-Kirati, Taous-Meriem; Elmetennani, Shahrazed

2017-01-01

Various examples of systems and methods are provided for Lyapunov control for uncertain systems. In one example, a system includes a process plant and a robust Lyapunov controller configured to control an input of the process plant. The robust

A CAMAC based knob controller for the LAMPF control system

International Nuclear Information System (INIS)

Smith, W.; Bjorklund, E.

1987-01-01

The control computer for the Los Alamos Meson Physics Facility (LAMPF) has been recently upgraded from an SEL-840 to a VAX 11/780 running the VMS operating system. As part of this upgrade, a CAMAC-based knob controller was developed for the new control system. The knobs allow the facility operators to have slew control over software selectable accelerator devices. An alphanumeric display associated with each knob monitors the progress of the selected device. This paper describes the system requirements for the new LAMPF knob controller, and the resulting hardware and software design

Automation of Aditya vacuum control system based on CODAC Core System

Energy Technology Data Exchange (ETDEWEB)

Raulji, Vismaysinh D., E-mail: vismay@ipr.res.in; Pujara, Harshad; Arambhadiya, Bharat; Jadeja, Kumarpalsinh; Bhatt, Shailesh; Rajpal, Rachana

2016-11-15

Highlights: • Monitor and control of vacuum control system based on CODAC Core System. • Communication between SIEMENS PLC and open source software EPICS. • With CODAC Core easy to configure and programming of slow controller. - Abstract: The main objective of vacuum control system is to provide ultrahigh vacuum for Aditya Tokamak operations. Aditya Vacuum vessel is having four vacuum pumping lines. To demonstrate implementation of automation; a study case is under taken by automating single Pumping Line of the Aditya vacuum system using CODAC Core System (CCS). Currently, vacuum system is operated manually. The CCS based control system allows remote control, monitoring, alarm handling of vacuum parameters. The CODAC Core System is the Linux based software package that is distributed by ITER Organization for the development of Plant System I&C software. CODAC Core System includes EPICS, CSS (Control System Studio) etc. CSS is used for HMI (Human Machine Interface), alarms and archives. SDD (Self Description Data) tool is used to configure plant system I&C. SDD Editor is an Eclipse based application to define the plant system, interface, I&C component, interfaced signals, configure variable. SCADA (Supervisory Control and Data Acquisition) system is developed in CSS. Data is transferred between PLC and CSS through EPICS. The complete system is tested with Aditya Vacuum Control System with process interlocks. Operator interface is also developed using Lab VIEW as a choice of the user. This paper will describe the salient features of the developed control system in detail.

FOOD SAFETY CONTROL SYSTEM IN CHINA

Institute of Scientific and Technical Information of China (English)

Liu Wei-jun; Wei Yi-min; Han Jun; Luo Dan; Pan Jia-rong

2007-01-01

Most countries have expended much effort to develop food safety control systems to ensure safe food supplies within their borders. China, as one of the world's largest food producers and consumers,pays a lot of attention to food safety issues. In recent years, China has taken actions and implemented a series of plans in respect to food safety. Food safety control systems including regulatory, supervisory,and science and technology systems, have begun to be established in China. Using, as a base, an analysis of the current Chinese food safety control system as measured against international standards, this paper discusses the need for China to standardize its food safety control system. We then suggest some policies and measures to improve the Chinese food safety control system.

Notions of local controllability and optimal feedforward control for quantum systems

International Nuclear Information System (INIS)

Chakrabarti, Raj

2011-01-01

Local controllability is an essential concept for regulation and control of time-varying nonlinear dynamical systems; in the classical control logic it is at the foundation of neighboring optimal feedback and feedforward control. We introduce notions of local controllability suited to feedforward control of classical input disturbances in bilinear quantum systems evolving on projective spaces and Lie groups. Tests for local controllability based on a Gramian matrix analogous to the nonlinear local controllability Gramian, which allow assessment of which trajectories can be regulated by perturbative feedforward in the presence of classical input noise, are presented. These notions explicitly incorporate system bilinearity and the geometry of quantum states into the definition of local controllability of quantum systems. Associated feedforward strategies are described.

Notions of local controllability and optimal feedforward control for quantum systems

Energy Technology Data Exchange (ETDEWEB)

Chakrabarti, Raj, E-mail: rchakra@purdue.edu [School of Chemical Engineering, Purdue University, West Lafayette, IN 47907 (United States)

2011-05-06

Local controllability is an essential concept for regulation and control of time-varying nonlinear dynamical systems; in the classical control logic it is at the foundation of neighboring optimal feedback and feedforward control. We introduce notions of local controllability suited to feedforward control of classical input disturbances in bilinear quantum systems evolving on projective spaces and Lie groups. Tests for local controllability based on a Gramian matrix analogous to the nonlinear local controllability Gramian, which allow assessment of which trajectories can be regulated by perturbative feedforward in the presence of classical input noise, are presented. These notions explicitly incorporate system bilinearity and the geometry of quantum states into the definition of local controllability of quantum systems. Associated feedforward strategies are described.

Radiation-hardened control system

International Nuclear Information System (INIS)

Vandermolen, R.I.; Smith, S.F.; Emery, M.S.

1993-01-01

A radiation-hardened bit-slice control system with associated input/output circuits was developed to prove that programmable circuits could be constructed to successfully implement intelligent functions in a highly radioactive environment. The goal for this effort was to design and test a programmable control system that could withstand a minimum total dose of 10 7 rads (gamma). The Radiation Hardened Control System (RHCS) was tested in operation at a dose rate that ranged up to 135 krad/h, with an average total dose of 10.75 Mrads. Further testing beyond the required 10 7 rads was also conducted. RHCS performed properly through the target dose of 10 7 rads, and sporadic intermittent failures in some programmable logic devices were noted after ∼ 13 Mrads

Globalization and localization of Management Control Systems

DEFF Research Database (Denmark)

Toldbod, Thomas; Israelsen, Poul

2014-01-01

Through an empirical case study this article examines the operation of multiple management control systems as a package in a Danish manufacturing company. The analysis focuses on four different management control systems; cybernetic controls, planning controls, reward controls, and administrative...... have more particular characteristics. Specifically, this study finds that cybernetic controls and administrative controls are designed as global management control systems. Planning controls are glocal systems and reward & compensation controls assume local characteristics. The finding leads...... controls, through the theoretical lens of globalization, localization, and glocalization. The analysis documents that these different management control systems are affected differently by the processes of globalization and localization, whereby some are universal throughout the organization and others...

Improving electrical equipment and control systems for shield integrated mining systems

Energy Technology Data Exchange (ETDEWEB)

Rabinovich, Z.M.; Starikov, B.Ya.; Kibrik, I.S.

1984-06-01

The design and operation are discussed for electrical equipment and control systems for the 1AShchM, the ANShch and the 2ANShch shield integrated face systems consisting of shield supports, coal plow and chain conveyor. The shield system is used for mining inclined and steep coal seams endangered by coal dust explosions, methane or rock bursts. Control and electrical system for 3 types of shield face mining systems is similar. It cuts energy supply when methane content at working faces exceeds the maximum permissible level, controls haulage rate and cutting rate of a coal plow, controls operation of shield supports (using the Sirena system), controls dust suppression system and its water consumption. The system is also equipped with communications equipment. Tests of the control and electrical system for the integrated shield system carried out in the im. Gagarin mine in the Ukraine are described. The VAUS III control system developed by Dongiprouglemash was tested.

Fuzzy logic control and optimization system

Science.gov (United States)

Lou, Xinsheng [West Hartford, CT

2012-04-17

A control system (300) for optimizing a power plant includes a chemical loop having an input for receiving an input signal (369) and an output for outputting an output signal (367), and a hierarchical fuzzy control system (400) operably connected to the chemical loop. The hierarchical fuzzy control system (400) includes a plurality of fuzzy controllers (330). The hierarchical fuzzy control system (400) receives the output signal (367), optimizes the input signal (369) based on the received output signal (367), and outputs an optimized input signal (369) to the input of the chemical loop to control a process of the chemical loop in an optimized manner.

Control system security in nuclear power plant

International Nuclear Information System (INIS)

Li Jianghai; Huang Xiaojin

2012-01-01

The digitalization and networking of control systems in nuclear power plants has brought significant improvements in system control, operation and maintenance. However, the highly digitalized control system also introduces additional security vulnerabilities. Moreover, the replacement of conventional proprietary systems with common protocols, software and devices makes these vulnerabilities easy to be exploited. Through the interaction between control systems and the physical world, security issues in control systems impose high risks on health, safety and environment. These security issues may even cause damages of critical infrastructures and threaten national security. The importance of control system security by reviewing several control system security incidents that happened in nuclear power plants was showed in recent years. Several key difficulties in addressing these security issues were described. Finally, existing researches on control system security and propose several promising research directions were reviewed. (authors)

Linear systems optimal and robust control

CERN Document Server

Sinha, Alok

2007-01-01

Introduction Overview Contents of the Book State Space Description of a Linear System Transfer Function of a Single Input/Single Output (SISO) System State Space Realizations of a SISO System SISO Transfer Function from a State Space Realization Solution of State Space Equations Observability and Controllability of a SISO System Some Important Similarity Transformations Simultaneous Controllability and Observability Multiinput/Multioutput (MIMO) Systems State Space Realizations of a Transfer Function Matrix Controllability and Observability of a MIMO System Matrix-Fraction Description (MFD) MFD of a Transfer Function Matrix for the Minimal Order of a State Space Realization Controller Form Realization from a Right MFD Poles and Zeros of a MIMO Transfer Function Matrix Stability Analysis State Feedback Control and Optimization State Variable Feedback for a Single Input System Computation of State Feedback Gain Matrix for a Multiinput System State Feedback Gain Matrix for a Multi...

Adding PCs to SLC Control System

International Nuclear Information System (INIS)

Lahey, T.; Levitt, S.; MacKenzie, R.; Spencer, N.; Underwood, K.

1993-05-01

The SLAC Controls Department has interfaced IBM-Compatible PCs to the SLC Control System, for use by the Final Focus Test Beam (FFTB) experimenters, who are building new accelerator equipment and developing and testing it at their home institutions. They will bring the equipment to SLAC and integrate it into the control system using a new software package. The machine physicists and operators will use the existing SLC control system applications and database device types to control and monitor the equipment. The PCs support a limited control environment: they run DOS and exchange messages with the existing control system via TCP/IP over ethernet, using the new SLC Area Message Service. This mechanism will also allow SLC to implement other commercial device controllers that can communicate over ethernet and run the same software interface code

Multiagent voltage and reactive power control system

Directory of Open Access Journals (Sweden)

I. Arkhipov

2014-12-01

Full Text Available This paper is devoted to the research of multiagent voltage and reactive power control system development. The prototype of the system has been developed by R&D Center at FGC UES (Russia. The control system architecture is based on the innovative multiagent system theory application that leads to the achievement of several significant advantages (in comparison to traditional control systems implementation such as control system efficiency enhancement, control system survivability and cyber security.

Environment control system

International Nuclear Information System (INIS)

Sammarone, D.G.

1978-01-01

Disclosed is a system for controlling the environment of an enclosed area in nuclear reactor installations. The system permits the changing of the environment from nitrogen to air, or from air to nitrogen, without the release of any radioactivity or process gas to the outside atmosphere

Adaptive control of discrete-time chaotic systems: a fuzzy control approach

International Nuclear Information System (INIS)

Feng Gang; Chen Guanrong

2005-01-01

This paper discusses adaptive control of a class of discrete-time chaotic systems from a fuzzy control approach. Using the T-S model of discrete-time chaotic systems, an adaptive control algorithm is developed based on some conventional adaptive control techniques. The resulting adaptively controlled chaotic system is shown to be globally stable, and its robustness is discussed. A simulation example of the chaotic Henon map control is finally presented, to illustrate an application and the performance of the proposed control algorithm

Framework for control system development

International Nuclear Information System (INIS)

Cork, C.; Nishimura, Hiroshi

1992-01-01

Control systems being developed for the present generation of accelerators will need to adapt to changing machine and operating state conditions. Such systems must also be capable of evolving over the life of the accelerator operation. In this paper we present a framework for the development of adaptive control systems

Framework for control system development

International Nuclear Information System (INIS)

Cork, C.; Nishimura, Hiroshi.

1991-11-01

Control systems being developed for the present generation of accelerators will need to adapt to changing machine and operating state conditions. Such systems must also be capable of evolving over the life of the accelerator operation. In this paper we present a framework for the development of adaptive control systems

PEP computer control system

International Nuclear Information System (INIS)

1979-03-01

This paper describes the design and performance of the computer system that will be used to control and monitor the PEP storage ring. Since the design is essentially complete and much of the system is operational, the system is described as it is expected to 1979. Section 1 of the paper describes the system hardware which includes the computer network, the CAMAC data I/O system, and the operator control consoles. Section 2 describes a collection of routines that provide general services to applications programs. These services include a graphics package, data base and data I/O programs, and a director programm for use in operator communication. Section 3 describes a collection of automatic and semi-automatic control programs, known as SCORE, that contain mathematical models of the ring lattice and are used to determine in real-time stable paths for changing beam configuration and energy and for orbit correction. Section 4 describes a collection of programs, known as CALI, that are used for calibration of ring elements

Control system for Siam photon source

CERN Document Server

Apiwatwaja, R; Isoyama, G; Ishii, T; Pairsuwan, W

2003-01-01

A new computer control system has been developed for Siam photon source, which is the first synchrotron light source in Thailand, personal computers and PLC's have been employed which are connected together through Ethernet. Man Machine Interface Stations (MMIS) at the front end act as a graphical user interface within Windows environment. The monitoring and controlling of individual devices is handled through several pairs of digital control station and the device interface located in each part of the synchrotron complex. The installation of the control system has been completed. The commissioning test of the control system is underway and the reliability of the system is on the positive side. Details of commissioning tests as well as characteristics of this newly built control system for the Siam photon source are described in this report.

Development of operator requested control system applications: Experience with the SLC control system at SLAC

International Nuclear Information System (INIS)

Stanek, M.

1995-01-01

The SLC Control system at SLAC has evolved into a powerful tool for operation of the accelerator and for troubleshooting the unique problems encountered in extracting maximum performance from the SLC. The evolution has included the development of many custom applications and user interface features generated from accelerator operator and accelerator physicist requests. These applications are written and maintained primarily by the Controls Software Engineering group, and not by the users themselves. The process of developing and supporting user requested control systems applications at SLAC is described, including the effects of organizational structure, formal and informal procedures, and control system architecture

Applying model predictive control to power system frequency control

OpenAIRE

Ersdal, AM; Imsland, L; Cecilio, IM; Fabozzi, D; Thornhill, NF

2013-01-01

16.07.14 KB Ok to add accepted version to Spiral Model predictive control (MPC) is investigated as a control method which may offer advantages in frequency control of power systems than the control methods applied today, especially in presence of increased renewable energy penetration. The MPC includes constraints on both generation amount and generation rate of change, and it is tested on a one-area system. The proposed MPC is tested against a conventional proportional-integral (PI) cont...

The NSTX Central Instrumentation and Control System

International Nuclear Information System (INIS)

G. Oliaro; J. Dong; K. Tindall; P. Sichta

1999-01-01

Earlier this year the National Spherical Torus Experiment (NSTX) at the Princeton Plasma Physics Laboratory achieved ''first plasma''. The Central Instrumentation and Control System was used to support plasma operations. Major elements of the system include the Process Control System, Plasma Control System, Network System, Data Acquisition System, and Synchronization System. This paper will focus on the Process Control System. Topics include the architecture, hardware interface, operator interface, data management, and system performance

Status of the BEPC control system

International Nuclear Information System (INIS)

Zhao Jijiu; Yan Yonghe; Zhan Mingchuan; Yu Yulan; Luo Huiying; Wang Yaru; Geng Xiaosong

1994-01-01

The control system of the Beijing Electron Positron Collider (BEPC) was built by the end of 1987. Since then, it has been running safely and reliably. Due to the tight construction schedule, we adopted the control system structure of the new SPEAR of SLAC, which was a centralized control system. The system was not performing very well due to various problems such as low CPU power, limited memory of the VAX-11/750 control computer, a bottle-neck of the VAX-CAMAC-Channel etc. Since 1991 we have therefore been working on upgrading it to a distributed control system based on DECnet. The old console will be replaced by VAX-4090 workstations. The status of the system and the progress of the upgrading work are presented in this paper. ((orig.))

PLCs for nuclear fire control system

International Nuclear Information System (INIS)

McArthur, Neil

1990-01-01

The new Thermal Oxide Reprocessing Plant (THORP) at British Nuclear Fuel's Sellafield site is a very large and complex system. This article describes the computerized control system used for fire damage control in the two main production areas, the head end and the chemical separation segments. Over one thousand fire dampers are controlled by an interlinking system of small computers linked to a main system in the central control room. The choice of hardware and software is also described. (UK)

Division 1137 property control system

Energy Technology Data Exchange (ETDEWEB)

Pastor, D.J.

1982-01-01

An automated data processing property control system was developed by Mobile and Remote Range Division 1137. This report describes the operation of the system and examines ways of using it in operational planning and control.

The Ganil computer control system renewal

International Nuclear Information System (INIS)

David, L.; Lecorche, E.; Luong, T.T.; Ulrich, M.

1990-01-01

Since 1982 the GANIL heavy ion accelerator has been under the control of 16-bit minicomputers MITRA, programmable logic controllers and microprocessorized Camac controllers, structured into a partially centralized system. This control system has to be renewed to meet the increasing demands of the accelerator operation which aims to provide higher quality ion beams under more reliable conditions. This paper gives a brief description of the existing control system and then discusses the main issues of the design and the implementation of the future control system: distributed powerful processors federated through Ethernet and flexible network-wide database access, VME standard and front-end microprocessors, enhanced color graphic tools and workstation based operator interface

Security of legacy process control systems : Moving towards secure process control systems

NARCIS (Netherlands)

Oosterink, M.

2012-01-01

This white paper describes solutions which organisations may use to improve the security of their legacy process control systems. When we refer to a legacy system, we generally refer to old methodologies, technologies, computer systems or applications which are still in use, despite the fact that

Siroco, a configurable robot control system

International Nuclear Information System (INIS)

Tejedor, B.G.; Maraggi, G.J.B.

1988-01-01

The SIROCO (Configurable Robot Control System) is an electronic system designed to work in applications where mechanized remote control equipment and robots are necessary especially in Nuclear Power Plants. The structure of the system (hardware and software) determines the following user characteristics: a) Reduction in the time spent in NDT and in radiation doses absorbed, due to remote control operation; b) possibility for full automation in NDT, c) the system can simultaneously control up to six axes and can generate movements in remote areas; and d) possibility for equipment unification, due to SIROCO being a configurable system. (author)

Ground test accelerator control system software

International Nuclear Information System (INIS)

Burczyk, L.; Dalesio, R.; Dingler, R.; Hill, J.; Howell, J.A.; Kerstiens, D.; King, R.; Kozubal, A.; Little, C.; Martz, V.; Rothrock, R.; Sutton, J.

1988-01-01

This paper reports on the GTA control system that provides an environment in which the automation of a state-of-the-art accelerator can be developed. It makes use of commercially available computers, workstations, computer networks, industrial 110 equipment, and software. This system has built-in supervisory control (like most accelerator control systems), tools to support continuous control (like the process control industry), and sequential control for automatic start-up and fault recovery (like few other accelerator control systems). Several software tools support these levels of control: a real-time operating system (VxWorks) with a real-time kernel (VRTX), a configuration database, a sequencer, and a graphics editor. VxWorks supports multitasking, fast context-switching, and preemptive scheduling. VxWorks/VRTX is a network-based development environment specifically designed to work in partnership with the UNIX operating system. A data base provides the interface to the accelerator components. It consists of a run time library and a database configuration and editing tool. A sequencer initiates and controls the operation of all sequence programs (expressed as state programs). A graphics editor gives the user the ability to create color graphic displays showing the state of the machine in either text or graphics form

The temporal requirement for vitamin A in the developing eye: mechanism of action in optic fissure closure and new roles for the vitamin in regulating cell proliferation and adhesion in the embryonic retina.

Science.gov (United States)

See, Angela Wai-Man; Clagett-Dame, Margaret

2009-01-01

Mammalian eye development requires vitamin A (retinol, ROL). The role of vitamin A at specific times during eye development was studied in rat fetuses made vitamin A deficient (VAD) after embryonic day (E) 10.5 (late VAD). The optic fissure does not close in late VAD embryos, and severe folding and collapse of the retina is observed at E18.5. Pitx2, a gene required for normal optic fissure closure, is dramatically downregulated in the periocular mesenchyme in late VAD embryos, and dissolution of the basal lamina does not occur at the optic fissure margin. The addition of ROL to late VAD embryos by E12.5 restores Pitx2 expression, supports dissolution of the basal lamina, and prevents coloboma, whereas supplementation at E13.5 does not. Surprisingly, ROL given as late as E13.5 completely prevents folding of the retina despite the presence of an open fetal fissure, showing that coloboma and retinal folding represent distinct VAD-dependent defects. Retinal folding due to VAD is preceded by an overall reduction in the percentage of cyclin D1 positive cells in the developing retina, (initially resulting in retinal thinning), as well as a dramatic reduction in the cell adhesion-related molecules, N-cadherin and beta-catenin. Reduction of retinal cell number combined with a loss of the normal cell-cell adhesion proteins may contribute to the collapse and folding of the retina that occurs in late VAD fetuses.

Access control and personal identification systems

CERN Document Server

Bowers, Dan M

1988-01-01

Access Control and Personal Identification Systems provides an education in the field of access control and personal identification systems, which is essential in selecting the appropriate equipment, dealing intelligently with vendors in purchases of the equipment, and integrating the equipment into a total effective system. Access control devices and systems comprise an important part of almost every security system, but are seldom the sole source of security. In order for the goals of the total system to be met, the other portions of the security system must also be well planned and executed

Indirect learning control for nonlinear dynamical systems

Science.gov (United States)

Ryu, Yeong Soon; Longman, Richard W.

1993-01-01

In a previous paper, learning control algorithms were developed based on adaptive control ideas for linear time variant systems. The learning control methods were shown to have certain advantages over their adaptive control counterparts, such as the ability to produce zero tracking error in time varying systems, and the ability to eliminate repetitive disturbances. In recent years, certain adaptive control algorithms have been developed for multi-body dynamic systems such as robots, with global guaranteed convergence to zero tracking error for the nonlinear system euations. In this paper we study the relationship between such adaptive control methods designed for this specific class of nonlinear systems, and the learning control problem for such systems, seeking to converge to zero tracking error in following a specific command repeatedly, starting from the same initial conditions each time. The extension of these methods from the adaptive control problem to the learning control problem is seen to be trivial. The advantages and disadvantages of using learning control based on such adaptive control concepts for nonlinear systems, and the use of other currently available learning control algorithms are discussed.

Nonlinear control synthesis for electrical power systems using controllable series capacitors

Energy Technology Data Exchange (ETDEWEB)

Manjarekar, N.S.; Banavar, Ravi N. [Indian Institute of Technology Bombay, Mumbai (India). Systems and Control Engineering

2012-07-01

In this work we derive asymptotically stabilizing control laws for electrical power systems using two nonlinear control synthesis techniques. For this transient stabilization problem the actuator considered is a power electronic device, a controllable series capacitor (CSC). The power system is described using two different nonlinear models - the second order swing equation and the third order flux-decay model. To start with, the CSC is modeled by the injection model which is based on the assumption that the CSC dynamics is very fast as compared to the dynamics of the power system and hence can be approximated by an algebraic equation. Here, by neglecting the CSC dynamics, the input vector g(x) in the open loop system takes a complex form - the injection model. Using this model, interconnection and damping assignment passivity-based control (IDA-PBC) methodology is demonstrated on two power systems: a single machine infinite bus (SMIB) system and a two machine system. Further, IDA-PBC is used to derive stabilizing controllers for power systems, where the CSC dynamics are included as a first order system. Next, we consider a different control methodology, immersion and invariance (I and I), to synthesize an asymptotically stabilizing control law for the SMIB system with a CSC. The CSC is described by a first order system. As a generalization of I and I, we incorporate the power balance algebraic constraints in the load bus to the SMIB swing equation, and extend the design philosophy to a class of differential algebraic systems. The proposed result is then demonstrated on another example: a two-machine system with two load buses and a CSC. The controller performances are validated through simulations for all cases.

Application of fuzzy logic control system for reactor feed-water control

International Nuclear Information System (INIS)

Iijima, T.; Nakajima, Y.

1994-01-01

The successful actual application of a fuzzy logic control system to the a nuclear Fugen nuclear power reactor is described. Fugen is a heavy-water moderated, light-water cooled reactor. The introduction of fuzzy logic control system has enabled operators to control the steam drum water level more effectively in comparison to a conventional proportional-integral (PI) control system

Control measurement system in purex process

International Nuclear Information System (INIS)

Mani, V.V.S.

1985-01-01

The dependence of a bulk facility handling Purex Process on the control measurement system for evaluating the process performance needs hardly be emphasized. process control, Plant control, inventory control and quality control are the four components of the control measurement system. The scope and requirements of each component are different and the measurement methods are selected accordingly. However, each measurement system has six important elements. These are described in detail. The quality assurance programme carried out by the laboratory as a mechanism through which the quality of measurements is regularly tested and stated in quantitative terms is also explained in terms of internal and external quality assurance, with examples. Suggestions for making the control measurement system more responsive to the operational needs in future are also briefly discussed. (author)

Feedback control and adaptive control of the energy resource chaotic system

International Nuclear Information System (INIS)

Sun Mei; Tian Lixin; Jiang Shumin; Xu Jun

2007-01-01

In this paper, the problem of control for the energy resource chaotic system is considered. Two different method of control, feedback control (include linear feedback control, non-autonomous feedback control) and adaptive control methods are used to suppress chaos to unstable equilibrium or unstable periodic orbits. The Routh-Hurwitz criteria and Lyapunov direct method are used to study the conditions of the asymptotic stability of the steady states of the controlled system. The designed adaptive controller is robust with respect to certain class of disturbances in the energy resource chaotic system. Numerical simulations are presented to show these results

Health-system strengthening and tuberculosis control.

Science.gov (United States)

Atun, Rifat; Weil, Diana E C; Eang, Mao Tan; Mwakyusa, David

2010-06-19

Weak health systems are hindering global efforts for tuberculosis care and control, but little evidence is available on effective interventions to address system bottlenecks. This report examines published evidence, programme reviews, and case studies to identify innovations in system design and tuberculosis control to resolve these bottlenecks. We outline system bottlenecks in relation to governance, financing, supply chain management, human resources, health-information systems, and service delivery; and adverse effects from rapid introduction of suboptimum system designs. This report also documents innovative solutions for disease control and system design. Solutions pursued in individual countries are specific to the nature of the tuberculosis epidemic, the underlying national health system, and the contributors engaged: no one size fits all. Findings from countries, including Bangladesh, Cambodia, India, Tanzania, Thailand, and Vietnam, suggest that advances in disease control and system strengthening are complementary. Tuberculosis care and control are essential elements of health systems, and simultaneous efforts to innovate systems and disease response are mutually reinforcing. Highly varied and context-specific responses to tuberculosis show that solutions need to be documented and compared to develop evidence-based policies and practice. Copyright 2010 Elsevier Ltd. All rights reserved.

An approach of partial control design for system control and synchronization

International Nuclear Information System (INIS)

Hu Wuhua; Wang Jiang; Li Xiumin

2009-01-01

In this paper, a general approach of partial control design for system control and synchronization is proposed. It turns control problems into simpler ones by reducing their control variables. This is realized by utilizing the dynamical relations between variables, which are described by the dynamical relation matrix and the dependence-influence matrix. By adopting partial control theory, the presented approach provides a simple and general way to stabilize systems to their partial or whole equilibriums, or to synchronize systems with their partial or whole states. Further, based on this approach, the controllers can be simplified. Two examples of synchronizing chaotic systems are given to illustrate its effectiveness.

CEBAF control system

International Nuclear Information System (INIS)

Bork, R.; Grubb, C.; Lahti, G.; Navarro, E.; Sage, J.

1989-01-01

A logic-based computer control system is in development at CEBAF. This Unix/C language software package, running on a distributed, hierarchical system of workstation and supervisory minicomputers, interfaces to hardware via CAMAC. Software aspects to be covered are ladder logic, interactive database generation, networking, and graphic user interfaces. 1 fig

RF control system of the HIMAC synchrotron

International Nuclear Information System (INIS)

Kanazawa, M.; Sato, K.; Itano, A.

1992-01-01

An RF control system of the HIMAC synchrotron has been constructed. In this control system we have adopted a digital feed back system with a digital synthesizer (DS). Combining a high power system, performance of the control system have been tested in a factory (Toshiba) with a simulator circuit of the synchrotron oscillation. Following this test, We had beam acceleration test with this control system at TARN-II in INS (Institute for Nuclear Study, University of Tokyo). This paper describes the RF control system and its tested results. (author)

EBR-II Cover Gas Cleanup System upgrade process control system structure

International Nuclear Information System (INIS)

Carlson, R.B.; Staffon, J.D.

1992-01-01

The Experimental Breeder Reactor II (EBR-II) Cover Gas Cleanup System (CGCS) control system was upgraded in 1991 to improve control and provide a graphical operator interface. The upgrade consisted of a main control computer, a distributed control computer, a front end input/output computer, a main graphics interface terminal, and a remote graphics interface terminal. This paper briefly describes the Cover Gas Cleanup System and the overall control system; describes the main control computer hardware and system software features in more detail; and, then, describes the real-time control tasks, and how they interact with each other, and how they interact with the operator interface task

Guaranteed Cost Fault-Tolerant Control for Networked Control Systems with Sensor Faults

Directory of Open Access Journals (Sweden)

Qixin Zhu

2015-01-01

Full Text Available For the large scale and complicated structure of networked control systems, time-varying sensor faults could inevitably occur when the system works in a poor environment. Guaranteed cost fault-tolerant controller for the new networked control systems with time-varying sensor faults is designed in this paper. Based on time delay of the network transmission environment, the networked control systems with sensor faults are modeled as a discrete-time system with uncertain parameters. And the model of networked control systems is related to the boundary values of the sensor faults. Moreover, using Lyapunov stability theory and linear matrix inequalities (LMI approach, the guaranteed cost fault-tolerant controller is verified to render such networked control systems asymptotically stable. Finally, simulations are included to demonstrate the theoretical results.

The Effect of a Voice Activity Detector on the Speech Enhancement

DEFF Research Database (Denmark)

Dau, Torsten; Catic, Jasmina; Buchholz, Jörg

2010-01-01

A multimicrophone speech enhancement algorithm for binaural hearing aids that preserves interaural time delays was proposed recently. The algorithm is based on multichannel Wiener filtering and relies on a voice activity detector (VAD) for estimation of second-order statistics. Here, the effect...... of a VAD on the speech enhancement of this algorithm was evaluated using an envelopebased VAD, and the performance was compared to that achieved using an ideal error-free VAD. The performance was considered for stationary directional noise and nonstationary diffuse noise interferers at input SNRs from −10...

The alcator C-MOD control system

International Nuclear Information System (INIS)

Bosco, J.; Fairfax, S.

1992-01-01

The Alcator C-MOD experiment includes over 30 engineering and diagnostic subsystems. The control system hardware and software is a mixture of custom and commercial products which includes sensors, signal conditioners, hard-wired controls, programmable logic controllers, displays, a hybrid analog/digital computer, networked personal computers, and networked VAX workstations. This paper describes the computer-based portions of the control system. The control system coordinates all C-MOD systems including power, vacuum, heating and cooling, access control, plasma shape and position control, and diagnostics. Programmable logic controllers (PLC's) are located near each subsystem. The control room is isolated by fiber optics. Functions that are essential to personnel or equipment safety (e.g. access control) are implemented in hardwired logic and monitored but not controlled by the PLC's. The initial configuration will include over 25 Allen-Bradley PLC-5 units. The PLCs in each subsystem are connected to personal computers (PC's) in the control room. The PC's provide graphical displays and operator interface. The Pc's are networked and share process data with each other and with a master control console and a large mimic panel

Development of the automatic control rod operation system for JOYO. Verification of automatic control rod operation guide system

International Nuclear Information System (INIS)

Terakado, Tsuguo; Suzuki, Shinya; Kawai, Masashi; Aoki, Hiroshi; Ohkubo, Toshiyuki

1999-10-01

The automatic control rod operation system was developed to control the JOYO reactor power automatically in all operation modes(critical approach, cooling system heat up, power ascent, power descent), development began in 1989. Prior to applying the system, verification tests of the automatic control rod operation guide system was conducted during 32nd duty cycles of JOYO' from Dec. 1997 to Feb. 1998. The automatic control rod operation guide system consists of the control rod operation guide function and the plant operation guide function. The control rod operation guide function provides information on control rod movement and position, while the plant operation guide function provide guidance for plant operations corresponding to reactor power changes(power ascent or power descent). Control rod insertion or withdrawing are predicted by fuzzy algorithms. (J.P.N.)

Bee Venom Ameliorates Cognitive Dysfunction Caused by Neuroinflammation in an Animal Model of Vascular Dementia.

Science.gov (United States)

Cai, Mudan; Lee, Jun Hwan; Yang, Eun Jin

2017-10-01

Vascular dementia (VaD) is caused by the reduction of blood supply by vessel occlusion and is characterized by progressive cognitive decline. VaD incidence has been growing due to the aging population, placing greater strain on social and economic resources. However, the pathological mechanisms underlying VaD remain unclear. Many studies have used the bilateral common carotid artery occlusion (BCCAO) animal model to investigate potential therapeutics for VaD. In this study, we investigated whether bee venom (BV) improves cognitive function and reduces neuroinflammation in the hippocampus of BCCAO animals. Animals were randomly divided into three groups: a sham group (n = 15), BCCAO control group (n = 15), and BV-treated BCCAO group (n = 15). BCCAO animals were treated with 0.1 μg/g BV at ST36 ("Joksamli" acupoint) four times every other day. In order to investigate the effect of BV treatment on cognitive function, we performed a Y-maze test. In order to uncover any potential relationship between these results and neuroinflammation, we also performed Western blotting in the BCCAO group. Animals that had been treated with BV showed an improved cognitive function and a reduced expression of neuroinflammatory proteins in the hippocampus, including Iba-1, TLR4, CD14, and TNF-α. Furthermore, we demonstrated that BV treatment increased pERK and BDNF in the hippocampus. The present study thus underlines the neuroprotective effect of BV treatment against BCCAO-induced cognitive impairment and neuroinflammation. Our findings suggest that BV may be an effective complementary treatment for VaD, as it may improve cognitive function and attenuate neuroinflammation associated with dementia.

Ares I Flight Control System Design

Science.gov (United States)

Jang, Jiann-Woei; Alaniz, Abran; Hall, Robert; Bedrossian, Nazareth; Hall, Charles; Ryan, Stephen; Jackson, Mark

2010-01-01

The Ares I launch vehicle represents a challenging flex-body structural environment for flight control system design. This paper presents a design methodology for employing numerical optimization to develop the Ares I flight control system. The design objectives include attitude tracking accuracy and robust stability with respect to rigid body dynamics, propellant slosh, and flex. Under the assumption that the Ares I time-varying dynamics and control system can be frozen over a short period of time, the flight controllers are designed to stabilize all selected frozen-time launch control systems in the presence of parametric uncertainty. Flex filters in the flight control system are designed to minimize the flex components in the error signals before they are sent to the attitude controller. To ensure adequate response to guidance command, step response specifications are introduced as constraints in the optimization problem. Imposing these constraints minimizes performance degradation caused by the addition of the flex filters. The first stage bending filter design achieves stability by adding lag to the first structural frequency to phase stabilize the first flex mode while gain stabilizing the higher modes. The upper stage bending filter design gain stabilizes all the flex bending modes. The flight control system designs provided here have been demonstrated to provide stable first and second stage control systems in both Draper Ares Stability Analysis Tool (ASAT) and the MSFC 6DOF nonlinear time domain simulation.

Novel electro-hydraulic position control system for primary mirror supporting system

Directory of Open Access Journals (Sweden)

Xiongbin Peng

2016-05-01

Full Text Available In the field of modern large-scale telescope, primary mirror supporting system technology faces the difficulties of theoretically uniform output force request and bias compensation. Therefore, a novel position control system combining hydraulic system with servo motor system is introduced. The novel system ensures uniform output force on supporting points without complicating the mechanical structure. The structures of both primary mirror supporting system and novel position system are described. Then, the mathematical model of novel position control system is derived for controller selection. A proportional–derivative controller is adopted for simulations and experiments of step response and triangle path tracking. The results show that proportional–derivative controller guarantees the system with micrometer-level positioning ability. A modified proportional–derivative controller is utilized to promote system behavior with faster response overshoot. The novel position control system is then applied on primary mirror supporting system. Coupling effect is observed among actuator partitions, and relocation of virtual pivot supporting point is chosen as the decoupling measurement. The position keeping ability of the primary mirror supporting system is verified by rotating the mirror cell at a considerably high rate. The experiment results show that the decoupled system performs better with smaller bias and shorter recovery time.

Remote diagnosis system for control and instrumentation systems

International Nuclear Information System (INIS)

Ito, Tetsuo; Suzuki, Satoshi; Nagaoka, Yukio.

1990-01-01

Control and instrumentation (C and I) systems for nuclear power plants tend to consist of many distributed digital controllers connected with transmission networks. Important parts of the C and I systems are redundantly constructed so that the failure of a component does not readily have a critical effect on the plant operation. It is necessary, however, to localize the faulty component for establishing better availability and maintainability of the plant. To diagnose failure of the C and I systems effectively, a remote diagnosis system is required that diagnoses anomalies of their controllers remotely from a central control room and identifies the fault location. Various fault diagnosis methods that apply artificial intelligence have been proposed for electronic circuits. Their knowledge bases are classified into two categories. One is rule-based knowledge, describing relations between anomaly phenomena and causes. The other is structure-based knowledge, which represents the configuration and functions of diagnosed objects. Though the latter is more suitable for deep inference, it is difficult to use for describing the detailed structure of large-scaled digital C and I systems. Then, a fault diagnosis system was developed that uses both knowledge bases and offers substantial man/machine interface functions for practical use

Robust control of time-delay chaotic systems

International Nuclear Information System (INIS)

Hua Changchun; Guan Xinping

2003-01-01

Robust control problem of nonlinear time-delay chaotic systems is investigated. For such uncertain systems, we propose adaptive feedback controller and novel nonlinear feedback controller. They are both independent of the time delay and can render the corresponding closed-loop systems globally uniformly ultimately bounded stable. The simulations on controlling logistic system are made and the results show the controllers are feasible

The TRISTAN control system

International Nuclear Information System (INIS)

Kurokawa, Shinichi; Akiyama, Atsuyoshi; Ishii, Kazuhiro; Kadokura, Eiichi; Katoh, Tadahiko; Kawamoto, Takashi; Kikutani, Eiji; Kimura, Yoshitaka; Koiso, Haruyo; Komada, Ichitaka; Kudo, Kikuo; Naito, Takashi; Oide, Katsunobu; Takeda, Shigeru; Uchino, Kenji; Urakawa, Junji; Shinomoto, Manabu; Kurihara, Michio; Abe, Kenichi

1986-01-01

The 8 GeV accumulation ring and the 30 GeV main ring of TRISTAN, an accelerator-storage ring complex at KEK, are controlled by a highly computerized control system. Twenty-four minicomputers are linked by optical fiber cables to form an N-to-N token ring network. The transmission speed on the cables is 10 Mbps. From each minicomputer, a CAMAC serial highway extends to the controlled equipment. At present, twenty minicomputers are connected to the network and are used to control the accumulation ring. The software system is based on the NODAL language devised at the CERN SPS. The KEK NODAL system retains main features of the original NODAL: the interpretive scheme, the multi-computer programming facility, and the data-module concept. In addition, it has the following features: (1) fast execution due to the compiler-interpreter method, (2) a multi-computer file system (3), a full-screen editing facility, and (4) a dynamic linkage scheme for data modules and NODAL functions. The accelerators are operated through five operator consoles, each of which is mangaged by one minicomputer in the network. An operator console contains two 20-inch high-resolution color graphic displays, a pair of touch-panels, and ten small TV monitors. One touch-panel is used to select a program and a piece of equipment to be controlled; the other is used mainly to perform the console actions. (orig.)

Model based control of refrigeration systems

Energy Technology Data Exchange (ETDEWEB)

Sloth Larsen, L.F.

2005-11-15

The subject for this Ph.D. thesis is model based control of refrigeration systems. Model based control covers a variety of different types of controls, that incorporates mathematical models. In this thesis the main subject therefore has been restricted to deal with system optimizing control. The optimizing control is divided into two layers, where the system oriented top layers deals with set-point optimizing control and the lower layer deals with dynamical optimizing control in the subsystems. The thesis has two main contributions, i.e. a novel approach for set-point optimization and a novel approach for desynchronization based on dynamical optimization. The focus in the development of the proposed set-point optimizing control has been on deriving a simple and general method, that with ease can be applied on various compositions of the same class of systems, such as refrigeration systems. The method is based on a set of parameter depended static equations describing the considered process. By adapting the parameters to the given process, predict the steady state and computing a steady state gradient of the cost function, the process can be driven continuously towards zero gradient, i.e. the optimum (if the cost function is convex). The method furthermore deals with system constrains by introducing barrier functions, hereby the best possible performance taking the given constrains in to account can be obtained, e.g. under extreme operational conditions. The proposed method has been applied on a test refrigeration system, placed at Aalborg University, for minimization of the energy consumption. Here it was proved that by using general static parameter depended system equations it was possible drive the set-points close to the optimum and thus reduce the power consumption with up to 20%. In the dynamical optimizing layer the idea is to optimize the operation of the subsystem or the groupings of subsystems, that limits the obtainable system performance. In systems

Complications related to the use of an intraventricular access device for the treatment of leptomeningeal metastases from solid tumor: a single centre experience in 112 patients.

Science.gov (United States)

Zairi, Fahed; Le Rhun, Emilie; Bertrand, Nicolas; Boulanger, Thomas; Taillibert, Sophie; Aboukais, Rabih; Assaker, Richard; Chamberlain, Marc C

2015-09-01

Ventricular access devices (VAD) offer several advantages compared to intralumbar injections for the administration of intra-CSF agents in the treatment of leptomeningeal metastases (LM). However, there are few prospective studies reporting on complications with the use of VADs. All complications were prospectively collected that pertained to the implantation and use of a VAD in consecutive patients with solid tumor-related LM from June 2006 to December 2013. Clinical follow-up was every 2 weeks during the initial 2 months of treatment and then once monthly. Complete neuraxis MRI was performed at baseline and then every 2-3 months. A total of 112 patients (88 women) with a mean age of 51.1 years (range 26-73) were included. Primary cancers included breast (79 patients), lung (12) and melanoma (6). All patients were treated with intra-CSF liposomal cytarabine. 72 % of the patients received concomitant systemic and intra-CSF chemotherapy. The placement of the VAD was performed under local anesthesia in all cases. The mean operative time was 15 min and no perioperative complications were reported. The mean number of intraventricular injections per patient was 9.34 (range 1-47). A total of 11 complications in 11 patients were seen including 7 infections, 1 intracranial hemorrhage, 2 instances of symptomatic leukoencephalopathy and 1 catheter malpositioning. 8 complications required an operation and 1 complication was fatal. The use of a VAD is safe and may improve patients' comfort and compliance with LM-directed therapy.

Computer Controlled Portable Greenhouse Climate Control System for Enhanced Energy Efficiency

Science.gov (United States)

Datsenko, Anthony; Myer, Steve; Petties, Albert; Hustek, Ryan; Thompson, Mark

2010-04-01

This paper discusses a student project at Kettering University focusing on the design and construction of an energy efficient greenhouse climate control system. In order to maintain acceptable temperatures and stabilize temperature fluctuations in a portable plastic greenhouse economically, a computer controlled climate control system was developed to capture and store thermal energy incident on the structure during daylight periods and release the stored thermal energy during dark periods. The thermal storage mass for the greenhouse system consisted of a water filled base unit. The heat exchanger consisted of a system of PVC tubing. The control system used a programmable LabView computer interface to meet functional specifications that minimized temperature fluctuations and recorded data during operation. The greenhouse was a portable sized unit with a 5' x 5' footprint. Control input sensors were temperature, water level, and humidity sensors and output control devices were fan actuating relays and water fill solenoid valves. A Graphical User Interface was developed to monitor the system, set control parameters, and to provide programmable data recording times and intervals.

Wireless Remote Control System

Directory of Open Access Journals (Sweden)

Adrian Tigauan

2012-06-01

Full Text Available This paper presents the design of a wireless remote control system based on the ZigBee communication protocol. Gathering data from sensors or performing control tasks through wireless communication is advantageous in situations in which the use of cables is impractical. An Atmega328 microcontroller (from slave device is used for gathering data from the sensors and transmitting it to a coordinator device with the help of the XBee modules. The ZigBee standard is suitable for low-cost, low-data-rate and low-power wireless networks implementations. The XBee-PRO module, designed to meet ZigBee standards, requires minimal power for reliable data exchange between devices over a distance of up to 1600m outdoors. A key component of the ZigBee protocol is the ability to support networking and this can be used in a wireless remote control system. This system may be employed e.g. to control temperature and humidity (SHT11 sensor and light intensity (TSL230 sensor levels inside a commercial greenhouse.

Management control system description

Energy Technology Data Exchange (ETDEWEB)

Bence, P. J.

1990-10-01

This Management Control System (MCS) description describes the processes used to manage the cost and schedule of work performed by Westinghouse Hanford Company (Westinghouse Hanford) for the US Department of Energy, Richland Operations Office (DOE-RL), Richland, Washington. Westinghouse Hanford will maintain and use formal cost and schedule management control systems, as presented in this document, in performing work for the DOE-RL. This MCS description is a controlled document and will be modified or updated as required. This document must be approved by the DOE-RL; thereafter, any significant change will require DOE-RL concurrence. Westinghouse Hanford is the DOE-RL operations and engineering contractor at the Hanford Site. Activities associated with this contract (DE-AC06-87RL10930) include operating existing plant facilities, managing defined projects and programs, and planning future enhancements. This document is designed to comply with Section I-13 of the contract by providing a description of Westinghouse Hanford's cost and schedule control systems used in managing the above activities. 5 refs., 22 figs., 1 tab.

The Optimization of power reactor control system

International Nuclear Information System (INIS)

Danupoyo, S.D.

1997-01-01

A power reactor is an important part in nuclear powered electrical plant systems. Success in controlling the power reactor will establish safety of the whole power plant systems. Until now, the power reactor has been controlled by a classical control system that was designed based on output feedback method. To meet the safety requirements that are now more restricted, the recently used power reactor control system should be modified. this paper describes a power reactor control system that is designed based on a state feedback method optimized with LQG (Linear-quadrature-gaussian) method and equipped with a state estimator. A pressurized-water type reactor has been used as the model. by using a point kinetics method with one group delayed neutrons. the result of simulation testing shows that the optimized control system can control the power reactor more effective and efficient than the classical control system

Adaptive control of port-Hamiltonian systems

NARCIS (Netherlands)

Dirksz, D.A.; Scherpen, J.M.A.; Edelmayer, András

2010-01-01

In this paper an adaptive control scheme is presented for general port-Hamiltonian systems. Adaptive control is used to compensate for control errors that are caused by unknown or uncertain parameter values of a system. The adaptive control is also combined with canonical transformation theory for

A digital control and monitoring system for PWR waste-disposal systems

International Nuclear Information System (INIS)

Ueda, Toshiharu; Fuchigami, Kazuyuki; Shimozato, Masao; Takazawa, Kazuo

1982-01-01

Mitsubishi Electric has developed a digital control and monitoring system for PWR waste-disposal systems. This novel system has improved operability due to its automated operations and control, and integrated supervisory functions. The system includes other features to improve operability: sequence control by a control computer, direct-digital process control, integrated supervision of operation states by a supervisory computer and a high-speed dataway, and CRT interfacing between the computer and dataway. (author)

Reactor limit control system

International Nuclear Information System (INIS)

Rubbel, F.E.

1982-01-01

The very extensive use of limitations in the operational field between protection system and closed-loop controls is an important feature of German understanding of operational safety. The design of limitations is based on very large activities in the computational field but mostly on the high level of the plant-wide own commissioning experience of a turnkey contractor. Limitations combine intelligence features of closed-loop controls with the high availability of protection systems. (orig.)

A deterministic - approach controller design for electrohydraulic position servo control system

International Nuclear Information System (INIS)

Johari Osman

2000-01-01

This paper is concerned with the design of a tracking controller for controlling electrohydraulic position servo system based on a deterministic approach. The system is treated as an uncertain system with bounded uncertainties where the bounds are assumed known. It will be shown that the electrohydraulic position servo systems with the proposed controller is practically stable and tracks the desired position in spite of the uncertainties and nonlinearities present in the system (author)

Promises in intelligent plant control systems

International Nuclear Information System (INIS)

Otaduy, P.J.

1987-01-01

The control system is the brain of a power plant. The traditional goal of control systems has been productivity. However, in nuclear power plants the potential for disaster requires safety to be the dominant concern, and the worldwide political climate demands trustworthiness for nuclear power plants. To keep nuclear generation as a viable option for power in the future, trust is the essential critical goal which encompasses all others. In most of today's nuclear plants the control system is a hybrid of analog, digital, and human components that focuses on productivity and operates under the protective umbrella of an independent engineered safety system. Operation of the plant is complex, and frequent challenges to the safety system occur which impact on their trustworthiness. Advances in nuclear reactor design, computer sciences, and control theory, and in related technological areas such as electronics and communications as well as in data storage, retrieval, display, and analysis have opened a promise for control systems with more acceptable human brain-like capabilities to pursue the required goals. This paper elaborates on the promise of futuristic nuclear power plants with intelligent control systems and addresses design requirements and implementation approaches

Adaptive Dynamic Surface Control for Generator Excitation Control System

Directory of Open Access Journals (Sweden)

Zhang Xiu-yu

2014-01-01

Full Text Available For the generator excitation control system which is equipped with static var compensator (SVC and unknown parameters, a novel adaptive dynamic surface control scheme is proposed based on neural network and tracking error transformed function with the following features: (1 the transformation of the excitation generator model to the linear systems is omitted; (2 the prespecified performance of the tracking error can be guaranteed by combining with the tracking error transformed function; (3 the computational burden is greatly reduced by estimating the norm of the weighted vector of neural network instead of the weighted vector itself; therefore, it is more suitable for the real time control; and (4 the explosion of complicity problem inherent in the backstepping control can be eliminated. It is proved that the new scheme can make the system semiglobally uniformly ultimately bounded. Simulation results show the effectiveness of this control scheme.

The CMS tracker control system

Science.gov (United States)

Dierlamm, A.; Dirkes, G. H.; Fahrer, M.; Frey, M.; Hartmann, F.; Masetti, L.; Militaru, O.; Shah, S. Y.; Stringer, R.; Tsirou, A.

2008-07-01

The Tracker Control System (TCS) is a distributed control software to operate about 2000 power supplies for the silicon modules of the CMS Tracker and monitor its environmental sensors. TCS must thus be able to handle about 104 power supply parameters, about 103 environmental probes from the Programmable Logic Controllers of the Tracker Safety System (TSS), about 105 parameters read via DAQ from the DCUs in all front end hybrids and from CCUs in all control groups. TCS is built on top of an industrial SCADA program (PVSS) extended with a framework developed at CERN (JCOP) and used by all LHC experiments. The logical partitioning of the detector is reflected in the hierarchical structure of the TCS, where commands move down to the individual hardware devices, while states are reported up to the root which is interfaced to the broader CMS control system. The system computes and continuously monitors the mean and maximum values of critical parameters and updates the percentage of currently operating hardware. Automatic procedures switch off selected parts of the detector using detailed granularity and avoiding widespread TSS intervention.

Status of the ATLAS control system upgrade

International Nuclear Information System (INIS)

Munson, F.H.; Ferraretto, M.; Rutherford, B.

1992-01-01

Certain components of the ATLAS control system are two generations behind today's technology. It has been decided to upgrade the control system. in part, by replacing Digital Equipment Corporation (DEC) PDP-11 computers with present-day VAX technology. Two primary goals have been defined for the upgraded control system. The first of these goals is to keep additional ''in-house'' written software to a minimum, while providing the portability necessary to ensure the continued use of existing software. In an attempt to achieve this goal, commercially-available software has been utilized to provide a foundation for the final control-system configuration. The second goal is to develop the new control system, while not interfering with accelerator operations. This paper describes some of the motivation for upgrading the ATLAS control system, the basic features of the new control system, and the present status of the system's development

Overview of the NSTX Control System

International Nuclear Information System (INIS)

Sichta, P.; Dong, J.; Oliaro, G.; Roney, P.

2001-01-01

The National Spherical Torus Experiment (NSTX) is an innovative magnetic fusion device that was constructed by the Princeton Plasma Physics Laboratory (PPPL) in collaboration with the Oak Ridge National Laboratory, Columbia University, and the University of Washington at Seattle. Since achieving first plasma in 1999, the device has been used for fusion research through an international collaboration of more than twenty institutions. The NSTX is operated through a collection of control systems that encompass a wide range of technology, from hardwired relay controls to real-time control systems with giga-FLOPS of capability. This paper presents a broad introduction to the control systems used on NSTX, with an emphasis on the computing controls, data acquisition, and synchronization systems

Packaging of control system software

International Nuclear Information System (INIS)

Zagar, K.; Kobal, M.; Saje, N.; Zagar, A.; Sabjan, R.; Di Maio, F.; Stepanov, D.

2012-01-01

Control system software consists of several parts - the core of the control system, drivers for integration of devices, configuration for user interfaces, alarm system, etc. Once the software is developed and configured, it must be installed to computers where it runs. Usually, it is installed on an operating system whose services it needs, and also in some cases dynamically links with the libraries it provides. Operating system can be quite complex itself - for example, a typical Linux distribution consists of several thousand packages. To manage this complexity, we have decided to rely on Red Hat Package Management system (RPM) to package control system software, and also ensure it is properly installed (i.e., that dependencies are also installed, and that scripts are run after installation if any additional actions need to be performed). As dozens of RPM packages need to be prepared, we are reducing the amount of effort and improving consistency between packages through a Maven-based infrastructure that assists in packaging (e.g., automated generation of RPM SPEC files, including automated identification of dependencies). So far, we have used it to package EPICS, Control System Studio (CSS) and several device drivers. We perform extensive testing on Red Hat Enterprise Linux 5.5, but we have also verified that packaging works on CentOS and Scientific Linux. In this article, we describe in greater detail the systematic system of packaging we are using, and its particular application for the ITER CODAC Core System. (authors)

Vitamin A deficiency during pregnancy of HIV infected and non-infected women in tropical settings of Northwest Ethiopia

Directory of Open Access Journals (Sweden)

Bekele Assegedech

2011-07-01

Full Text Available Abstract Background Vitamin A deficiency (VAD is known to be a major public health problem among women of reproductive age in South East Asia and Africa. In Ethiopia, there are no studies conducted on serum vitamin A status of HIV-infected pregnant women. Therefore, the present study was aimed at determining the level of serum vitamin A and VAD among pregnant women with and without HIV infection in tropical settings of Northwest Ethiopia. Methods In this cross-sectional study, blood samples were collected from 423 pregnant women and from 55 healthy volunteers who visited the University of Gondar Hospital. Serum concentration of vitamin A was measured by high performance liquid chromatography. Results After controlling for total serum protein, albumin and demographic variables, the mean ± SD serum vitamin A in HIV seropositive pregnant women (0.96 ± 0.42 μmol/L was significantly lower than that in pregnant women without HIV infection (1.10 ± 0.45 μmol/L, P Conclusion The present study shows that VAD is a major public health problem among pregnant women in the tropical settings of Northwest Ethiopia. Considering the possible implications of VAD during pregnancy, we recommend multivitamin (which has a lower level of vitamin A supplementation in the care and management of pregnant women with or without HIV infection.

The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats.

Science.gov (United States)

Cao, Yanjing; Liang, Lizhen; Xu, Jian; Wu, Jiali; Yan, Yongxing; Lin, Ping; Chen, Qiang; Zheng, Fengming; Wang, Qin; Ren, Qian; Gou, Zengmei; Du, Yifeng

2016-05-01

Flavonoids have been shown to improve cognitive function and delay the dementia progression. However, the underlying mechanisms remain elusive. In the present study, we examined the effect of Scutellaria baicalensis stem-leaf total flavonoids (SSTFs) extracted from S. baicalensis Georgi on spatial learning and memory in a vascular dementia (VaD) rat model and explored its molecular mechanisms. The VaD rats were developed by permanent bilateral occlusion of the common carotid artery. Seven days after recovery, the VaD rats were treated with either 50 or 100 mg/kg of SSTF for 60 days. The spatial learning and memory was evaluated in the Morris water maze (MWM) test. The tau hyperphosphorylation and the levels of the related protein kinases or phosphatases were examined by western blot analysis. In VaD rats, SSTF treatment at 100 mg/kg significantly reduced the escape latency in training trial in MWM test. In the probe trial, SSTF treatment increased the searching time and travel distance in the target quadrant. SSTF treatment inhibited the tau phosphorylation in both cortex and hippocampus in VaD rats. Meanwhile, SSTF reduced the activity of glycogen synthase kinase 3β and cyclin-dependent kinase 5 in VaD rats. In contrast, SSTF treatment increased the level of the protein phosphatase 2A subunit B in VaD rats. SSTF treatment significantly improved the spatial cognition in VaD rats. Our results suggest that SSTF may alleviate tau-hyperphosphorylation-induced neurotoxicity through coordinating the activity of kinases and phosphatase after a stroke. SSTF may be developed into promising novel therapeutics for VaD. © The Author 2016. Published by ABBS Editorial Office in association with Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.

Model based controls and the AGS booster controls system architecture

International Nuclear Information System (INIS)

Casella, R.A.

1987-01-01

For the past three years the Accelerator Controls Section has been responsible for the development of the Heavy Ion Transfer Line (HITL) used to inject heavy ions created at the Tandem Van de Graaff into the Alternating Gradient Synchrotron (AGS). This was recognized as an opportunity to test new ideas for control of a beam line, which if successful, could be implemented in an upgrade of the existing control system for the AGS. The in place control system for the AGS consisted of DEC PDP10 computer as the primary computer interface to the accelerator via three control room consoles, and keeper of the device database. For the HITL project it was decided to make the control system a true distributed network putting more computing power down at the device level via intelligent subsystems. A network of Apollo workstations was added at the host level. Apollos run a distributed operating system and are connected to each other by the Domain Token Ring Network. The Apollos were seen as the new primary computers for consoles with each console containing at least one Apollo. These hosts and all other subsystems are connected to each other via an in house developed LAN (RELWAY). The design of the control system developed for HITL was mostly successful. The proposed AGS Booster is designed to be a synchrotron injector for the AGS. With the forthcoming development of the Booster for the AGS an opportunity has again developed to implement new ideas for accelerator control. One weakness of the HITL control system is the limited cpu power and poor debugging facilities of the stations

ISABELLE control system: design concepts

International Nuclear Information System (INIS)

Humphrey, J.W.

1979-01-01

ISABELLE is a Department of Energy funded proton accelerator/storage ring being built at Brookhaven National Laboratory (Upton, Long Island, New York). It is large (3.8 km circumference) and complicated (approx. 30,000 monitor and control variables). It is based on superconducting technology. Following the example of previous accelerators, ISABELLE will be operated from a single control center. The control system will be distributed and will incorporate a local computer network. An overview of the conceptual design of the ISABELLE control system will be presented

Manual control of unstable systems

Science.gov (United States)

Allen, R. W.; Hogue, J. R.; Parseghian, Z.

1986-01-01

Under certain operational regimes and failure modes, air and ground vehicles can present the human operator with a dynamically unstable or divergent control task. Research conducted over the last two decades has explored the ability of the human operator to control unstable systems under a variety of circumstances. Past research is reviewed and human operator control capabilities are summarized. A current example of automobile directional control under rear brake lockup conditions is also reviewed. A control system model analysis of the driver's steering control task is summarized, based on a generic driver/vehicle model presented at last year's Annual Manual. Results from closed course braking tests are presented that confirm the difficulty the average driver has in controlling the unstable directional dynamics arising from rear wheel lockup.

Remote Control of an Inverted Pendulum System for Intelligent Control Education

Directory of Open Access Journals (Sweden)

Seul Jung

2011-08-01

Full Text Available This paper presents a remote control task of an inverted pendulum system for intelligent control education. The inverted pendulum moving on the guided rail is required to maintain balancing while it follows the desired trajectory commanded remotely by a joystick operated by a user. Position commands for the inverted pendulum system are given by a joystick through the network. The inverted pendulum system is controlled by a neural network control method. The corresponding control results are confirmed through experimental studies.

LEDA LLRF control system characterization

International Nuclear Information System (INIS)

Regan, A.H.; Balleyguier, P.; Ziomek, C.D.

1998-01-01

The Low Energy Demonstration Accelerator (LEDA) for the Accelerator for the Production of Tritium (APT) project will be built at Los Alamos National Laboratory. The low-level RF (LLRF) control system portion of this accelerator must perform many functions, of which the primary one is controlling the RF fields in the accelerating cavities. Plans have been made to provide for on-line characterization of the LLRF control system and the complete RF system through use of stimulus and response buffers, and a digital signal processor built into the field control system electronics. The purpose of this circuitry is to characterize the behavior of the entire RF system (klystron, waveguides, high power splitters, accelerator cavity, etc.). This characterization feature can be used to measure the performance of the closed loop system with respect to the open loop system, to provide an automated way to set loop parameters, to determine the cavity Q-curve, and to detect any abnormal behavior in the RF chain. The types of measurements include frequency and time-domain responses to given perturbations, amplitude modulations, etc. This paper will discuss types of algorithms that can be implemented and present a description and block diagram of the electronics to be used

The new Aladdin control system

International Nuclear Information System (INIS)

Stott, J.P.; Eisert, D.E.

1990-01-01

The preliminary design of the new control system for the Aladdin electron-storage-ring light source was described at the Los Alamos workshop and an updated report was given at the Villars conference. The new system is now almost completely installed and this paper is a final report on the project. The major features of the system are the following: commercial hardware is used throughout the computer, network and microcomputer systems; the operator consoles and the device-control microcomputers are linked by Ethernet; VAXstations with keyboard and track-ball input devices are used in the operator consoles; the microcomputers use 68000-based single-board computers and VMEbus backplanes; the main magnet power supplies contain intelligent controllers which are linked to a microcomputer by a multidrop serial link; the microcomputer software is developed on the VAXstations; it is downloaded into RAM and debugged over the Ethernet before being burned into EPROMs for operational use. This paper describes the design of the system, highlighting changes from the previous proposals, and discusses the aspects which allowed the control system of an operating facility to be rebuilt without requiring or causing any significant downtime. The performance of the new system and possible future improvements are also discussed. (orig.)

Upgrading the Fermilab Linac local control system

International Nuclear Information System (INIS)

McCrory, E.S.; Goodwin, R.W.; Shea, M.F.

1991-02-01

A new control system for the Fermilab Linac is being designed, built and implemented. First, the nine-year-old linac control system is being replaced. Second, a control system for the new 805 MHz part of the linac is being built. The two systems are essentially identical, so that when the installations are complete, we will still have a single Linac Control System. 8 refs., 5 figs

Radiation control system

International Nuclear Information System (INIS)

Murao, Mitsuo.

1985-01-01

Purpose: To rapidly and suitably performing planning and designation by radiation-working control systems in the radiation controlled area of nuclear power plant. Method: Various informations regarding radiation exposure are arranged and actual exposure data are statistically stored, to thereby perform forecasting calculation for the radiation exposure upon workings in the plurality of working regions in the radiation controlled area. Based on the forecast values and the registered workers' exposure dose in the past workings are alocated successively such that the total exposure does upon conducting the workings is less than the limited value, to prepare working plans in the areas. Further, procedures for preparing a series of documents regarding the workings in the radiation area are automated to rapidly and properly provide the informations serving to the planning and designation for the radiation workings. As a result, the radiation managers' burnden can be mitigated and an efficient working management system can be provided, in view of the exposure management and personal management. (Kamimura, M.)

HYBRID VEHICLE CONTROL SYSTEM

Directory of Open Access Journals (Sweden)

V. Dvadnenko

2016-06-01

Full Text Available The hybrid vehicle control system includes a start–stop system for an internal combustion engine. The system works in a hybrid mode and normal vehicle operation. To simplify the start–stop system, there were user new possibilities of a hybrid car, which appeared after the conversion. Results of the circuit design of the proposed system of basic blocks are analyzed.

Control system and method for payload control in mobile platform cranes

Science.gov (United States)

Robinett, III, Rush D.; Groom, Kenneth N.; Feddema, John T.; Parker, Gordon G.

2002-01-01

A crane control system and method provides a way to generate crane commands responsive to a desired payload motion to achieve substantially pendulation-free actual payload motion. The control system and method apply a motion compensator to maintain a payload in a defined payload configuration relative to an inertial coordinate frame. The control system and method can further comprise a pendulation damper controller to reduce an amount of pendulation between a sensed payload configuration and the defined payload configuration. The control system and method can further comprise a command shaping filter to filter out a residual payload pendulation frequency from the desired payload motion.

Controlling systems of cogeneration blocks

International Nuclear Information System (INIS)

Suriansky, J.; Suriansky, J. Ml.; Puskajler, J.

2007-01-01

In this article the main parts of cogeneration unit control system are described. Article is aimed on electric power measurement with electricity protection as with temperature system regulation. In conclusion of the article, the control algorithm with perspective of cogeneration solve is indicated. (authors)

Advanced Light Source control system

International Nuclear Information System (INIS)

Magyary, S.; Chin, M.; Cork, C.; Fahmie, M.; Lancaster, H.; Molinari, P.; Ritchie, A.; Robb, A.; Timossi, C.

1989-03-01

The Advanced Light Source (ALS) is a third generation 1--2 GeV synchrotron radiation source designed to provide ports for 60 beamlines. It uses a 50 MeV electron linac and 1.5 GeV, 1 Hz, booster synchrotron for injection into a 1--2 GeV storage ring. Interesting control problems are created because of the need for dynamic closed beam orbit control to eliminate interaction between the ring tuning requirements and to minimize orbit shifts due to ground vibrations. The extremely signal sensitive nature of the experiments requires special attention to the sources of electrical noise. These requirements have led to a control system design which emphasizes connectivity at the accelerator equipment end and a large I/O bandwidth for closed loop system response. Not overlooked are user friendliness, operator response time, modeling, and expert system provisions. Portable consoles are used for local operation of machine equipment. Our solution is a massively parallel system with >120 Mbits/sec I/O bandwidth and >1500 Mips computing power. At the equipment level connections are made using over 600 powerful Intelligent Local Controllers (ILC-s) mounted in 3U size Eurocard slots using fiber-optic cables between rack locations. In the control room, personal computers control and display all machine variables at a 10 Hz rate including the scope signals which are collected though the control system. Commercially available software and industry standards are used extensively. Particular attention is paid to reliability, maintainability and upgradeability. 10 refs., 11 figs