WorldWideScience

Sample records for vaccine composition 2004-2005

  1. End-of-year-closure 2004/2005

    CERN Multimedia

    Human Resources Department

    2004-01-01

    As announced in Weekly Bulletin Nº 3/2004, the Laboratory will be closed from Saturday 18 December 2004 to Sunday 2 January 2005 inclusive. This period consists of 16 days: 4 days' official holiday, i.e. 24, 25 and 31 December 2004 and 1st January 2005; 6 days' special paid leave in accordance with Article R II 4.34 of the Staff Regulations, i.e. 20, 21, 22, 27, 28, and 29 December 2004; 1 Saturday, i.e. 18 December 2004; 2 days, 23 December 2004 to compensate for 25 December 2004 and 30 December 2004 to compensate for 1st January 2005 (Article R II 4.33 of the Staff Regulations); 3 Sundays, i.e. 19 and 26 December 2004 and 2 January 2005. The first working day in the New Year will be Monday 3 January 2005. Further information will be available from Department Secretariats, specifically concerning the conditions applicable to members of the personnel who are required to work during this period. Human Resources Department Tel. 74474

  2. LULI 2004-2005 activity report; LULI rapport scientifique 2004-2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document gathers the main results obtained by scientists from the LULI (laboratory for the use of intense lasers) unit in 2004-2005. It is made up of 40 short articles and is organized around 5 topics: 1) laser-matter interaction, 2) hydrodynamics, shocks, material treatment, 3) atom physics, X-ray lasers, 4) progress in optics for power lasers, and 5) instrumentation and other advances.

  3. Higher demand and production in 2004, but growth wavers in 2005 : markets for paper, paperboard and woodpulp, 2004-2005

    Science.gov (United States)

    Peter J. Ince; Eduard Akim; Bernard Lombard; Tomas Parik

    2005-01-01

    Global pulp, paper and paperboard markets improved in 2004 and 2005, as indicated by generally higher prices for most pulp, paper and paperboard products in comparison with 2003. While growth in demand was quite robust in 2004, by the end of the first half of 2005, markets appeared more hesitant and prices appeared to waver or reach a plateau. Within the UNECE region,...

  4. Teatriankeet 2004/2005

    Index Scriptorium Estoniae

    2005-01-01

    Vastavad Ü. Aaloe, J. Allik, R. Avestik, M. Balbat, K. Eberhart, S. Karja, E. Kekelidze, M. Kolk, G. Kordemets, J. Kulli, V.-S. Maiste, R. Neimar, M. Pesti, P.-R. Purje, J. Rähesoo, A. Saro, I. Sillar, Ü. Tonts, L. Tormis, B. Tuch, V. Vahing. Nimetatud ka parimad lavastused 2004/2005 - "Julia" (Eesti Draamateater, lav. T. Ojasoo), "Tõde ja õigus" (Tallinna Linnateater, lav. E. Nüganen), "Põrgu wärk" (MTÜ R.A.A.A.M., lav. H. Toompere jun)

  5. Barriers to influenza vaccine uptake in obese people in Italy: Changes 2005-2013.

    Science.gov (United States)

    Barbadoro, Pamela; Recanatini, Claudia; Ponzio, Elisa; Illuminati, Diego; D'Errico, Marcello M; Prospero, Emilia

    2016-10-01

    Obesity is an independent risk factor for developing flu-related complications. The aim of this study was to analyze influenza vaccine uptake (VU) in the Italian obese, before and after the introduction of obesity among the national recommendations, and to evaluate factors associated to VU. The comparison of two editions of the national survey carried out in 2004-2005, before the inclusion of obese people among the specific high risk categories for flu complications, and in 2013, reaching a sample of 21,857 persons who declared to have a BMI>30. Multilevel logistic regression was used to evaluate potential independent predictors of influenza immunization. Influenza vaccination coverage was 27.16% in 2013, versus 31.61% in 2005. A significant reduction of VU was registered after the introduction of obesity among the high risk conditions, for which flu VU was recommended. Regression modeling, both in adults and in older people, confirmed that barriers to VU in 2013 were younger age, medium level of education, absence of chronic disease, smoking habit, and reporting no contacts with GPs during the previous 12months. Among those aged 65 or more, the role of regional policies was associated to VU. Immunization rates among young obese population are low, especially if not affected by comorbidities. Moreover, a reduction was registered in 2013 with respect to 2005. Flu vaccine uptake among the older population seems to be influenced by regional vaccination strategies. The development of novel strategy is warranted, especially among the young adults. Copyright © 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  6. JAERI TANDEM annual report 2004. April 1, 2004 - March 31, 2005

    International Nuclear Information System (INIS)

    Ishii, Tetsuro; Takeuchi, Suehiro; Oshima, Masumi; Nagame, Yuichiro; Chiba, Satoshi; Sataka, Masao

    2006-01-01

    This annual report describes research activities, which have been performed with the JAERI tandem accelerator and its energy booster from April 1, 2004 to March 31, 2005. Summary reports of 48 papers, and lists of publication, personnel and cooperative research with universities are contained. The JAERI (Japan Atomic Energy Research Institute) have been unified with JNC (Japan Nuclear Fuel Cycle Development Institute) and became JAEA (Japan Atomic Energy Agency) on October 1st, 2005. (author)

  7. Kansas Satellite Image Database (KSID) 2004-2005

    Data.gov (United States)

    Kansas Data Access and Support Center — The Kansas Satellite Image Database (KSID) 2004-2005 consists of terrain-corrected, precision rectified spring, summer, and fall Landsat 5 Thematic Mapper (TM)...

  8. Uptake of meningococcal conjugate vaccine among adolescents in large managed care organizations, United States, 2005: Demand, supply and seasonality

    Directory of Open Access Journals (Sweden)

    Wortley Pascale M

    2009-11-01

    Full Text Available Abstract Background In February 2005, the US Advisory Committee on Immunization Practices recommended the new meningococcal conjugate vaccine (MCV4 for routine use among 11- to 12-year-olds (at the preadolescent health-care visit, 14- to 15-year-olds (before high-school entry, and groups at increased risk. Vaccine distribution started in March; however, in July, the manufacturer reported inability to meet demand and widespread MCV4 shortages were reported. Our objectives were to determine early uptake patterns among target (11-12 and 14-15 year olds and non-target (13- plus 16-year-olds age groups. A post hoc analysis was conducted to compare seasonal uptake patterns of MCV4 with polysaccharide meningococcal (MPSV4 and tetanus diphtheria (Td vaccines. Methods We analyzed data for adolescents 11-16 years from five managed care organizations participating in the Vaccine Safety Datalink (VSD. For MCV4, we estimated monthly and cumulative coverage during 2005 and calculated risk ratios. For MPSV4 and Td, we combined 2003 and 2004 data and compared their seasonal uptake patterns with MCV4. Results Coverage for MCV4 during 2005 among the 623,889 11-16 years olds was 10%. Coverage for 11-12 and 14-15 year olds was 12% and 11%, respectively, compared with 8% for 13- plus 16-year-olds (p Conclusion A surge in vaccine uptake between June and August was observed among adolescents for MCV4, MPSV4 and Td vaccines. The increase in summer-time vaccinations and vaccination of non-targeted adolescents coupled with supply limitations likely contributed to the reported shortages of MCV4 in 2005.

  9. Official holidays in 2004 and end-of-year closure 2004/2005

    CERN Multimedia

    2004-01-01

    (Application of Articles R II 4.33 and R II 4.34 of the Staff Regulations) Official holidays in 2004 (in addition to the end-of-year holidays): - Friday, 9th April (Good Friday) - Monday, 12th April (Easter Monday) - Thursday, 20th May (Ascension Day) - Friday, 21st May Compensation granted for 1st May (Article R II 4.33 of the Staff Regulations) - Monday, 31st May (Whit Monday) - Thursday, 9th September ("Jeûne genevois") Annual closure of the site of the Organization and day of special leave granted by the Director-General: The Laboratory will be closed from Saturday, 17th December 2004 to Sunday, 2nd January 2005 inclusive (without deduction of annual leave). The first working day in the New Year will be Monday, 3rd January 2005. Human Resources Division Tel. 74128

  10. LULI 2004-2005 activity report

    International Nuclear Information System (INIS)

    2005-01-01

    This document gathers the main results obtained by scientists from the LULI (laboratory for the use of intense lasers) unit in 2004-2005. It is made up of 40 short articles and is organized around 5 topics: 1) laser-matter interaction, 2) hydrodynamics, shocks, material treatment, 3) atom physics, X-ray lasers, 4) progress in optics for power lasers, and 5) instrumentation and other advances

  11. Varicella vaccination coverage of children under two years of age in Germany

    Directory of Open Access Journals (Sweden)

    Reuss Annicka M

    2010-08-01

    Full Text Available Abstract Background Since July 2004, routine varicella vaccination is recommended by the German Standing Vaccination Committee in Germany. Health Insurance Funds started to cover vaccination costs at different time points between 2004 and 2006 in the Federal States. Nationwide representative data on vaccination coverage against varicella of children under two years of age are not available. We aimed to determine varicella vaccination coverage in statutory health insured children under two years of age in twelve German Federal States using data from associations of statutory health insurance physicians (ASHIPs, in order to investigate the acceptance of the recommended routine varicella vaccination programme. Methods We analysed data on varicella vaccination from 13 of 17 ASHIPs of the years 2004 to 2007. The study population consisted of all statutory health insured children under two years of age born in 2004 (cohort 2004 or 2005 (cohort 2005 in one of the studied regions. Vaccination coverage was determined by the number of children vaccinated under 2 years of age within the study population. Results Varicella vaccination coverage of children under two years of age with either one dose of the monovalent varicella vaccine or two doses of the measles, mumps, rubella, and varicella vaccine increased from 34% (cohort 2004 to 51% (cohort 2005 in the studied regions (p Conclusions Our study shows increasing varicella vaccination coverage of young children, indicating a growing acceptance of the routine varicella vaccination programme by the parents and physicians. We recommend further monitoring of vaccination coverage using data from ASHIPs to investigate acceptance of the routine vaccination programmes over time.

  12. Training in AB Department 2004/2005

    CERN Document Server

    Schinzel, Josi; CERN. Geneva. AB Department

    2006-01-01

    This note provides an overview of the training attended by members of the AB Department during the years 2004 and 2005, giving a break-down of the different courses and costs as well as training directions. It describes the organisation of training in the department, and evolution in training directions and planning.

  13. Surveillance van respiratoire infectieziekten in 2004/2005.

    NARCIS (Netherlands)

    Dijkstra, F.; Plas, S.M. van der; Wilbrink, B.; Jong, J.C. de; Bartelds, A.I.M.

    2005-01-01

    In order to gain more clear understanding of the epidemiology of a selection of respiratory infectious diseases in The Netherlands in the season 2004/2005, epidemiological data about a selection of respiratory syndromes and pathogens (influenza-like illnesses, other acute respiratory infections,

  14. Water, Ice, and Meteorological Measurements at South Cascade Glacier, Washington, Balance Years 2004 and 2005

    Science.gov (United States)

    Bidlake, William R.; Josberger, Edward G.; Savoca, Mark E.

    2007-01-01

    Winter snow accumulation and summer snow and ice ablation were measured at South Cascade Glacier, Washington, to estimate glacier mass-balance quantities for balance years 2004 and 2005. The North Cascade Range in the vicinity of South Cascade Glacier accumulated smaller than normal winter snowpacks during water years 2004 and 2005. Correspondingly, the balance years 2004 and 2005 maximum winter snow balances of South Cascade Glacier, 2.08 and 1.97 meters water equivalent, respectively, were smaller than the average of such balances since 1959. The 2004 glacier summer balance (-3.73 meters water equivalent) was the eleventh most negative during 1959 to 2005 and the 2005 glacier summer balance (-4.42 meters water equivalent) was the third most negative. The relatively small winter snow balances and unusually negative summer balances of 2004 and 2005 led to an overall loss of glacier mass. The 2004 and 2005 glacier net balances, -1.65 and -2.45 meters water equivalent, respectively, were the seventh and second most negative during 1953 to 2005. For both balance years, the accumulation area ratio was less than 0.05 and the equilibrium line altitude was higher than the glacier. The unusually negative 2004 and 2005 glacier net balances, combined with a negative balance previously reported for 2003, resulted in a cumulative 3-year net balance of -6.20 meters water equivalent. No equal or greater 3-year mass loss has occurred previously during the more than 4 decades of U.S. Geological Survey mass-balance measurements at South Cascade Glacier. Accompanying the glacier mass losses were retreat of the terminus and reduction of total glacier area. The terminus retreated at a rate of about 17 meters per year during balance year 2004 and 15 meters per year during balance year 2005. Glacier area near the end of balance years 2004 and 2005 was 1.82 and 1.75 square kilometers, respectively. Runoff from the basin containing the glacier and from an adjacent nonglacierized basin was

  15. Annual report of Kansai Research Establishment 2004. April 1, 2004 - March 31, 2005

    International Nuclear Information System (INIS)

    Harami, Taikan; Mizuki, Jun'ichiro; Aoki, Katsutoshi; Baba, Yuji; Murakami, Yoichi; Kobayashi, Keisuke; Sakai, Toru; Nagashima, Akira; Yamakawa, Koichi; Nagashima, Keisuke; Daido, Hiroyuki; Koike, Masato; Yamagiwa, Mituru; Bulanov, Sergei V.; Minehara, Eisuke

    2006-01-01

    This report is the sixth issue of the annual report of Kansai Research Establishment, Japan Atomic Energy Research Institute. It covers status report of R and D and results of experiments conducted at the Advanced Photon Research Center and Synchrotron Radiation Research Center during the period from April 1, 2004 to March 31, 2005. The JAERI (Japan Atomic Energy Research Institute) have been unified with JNC (Japan Nuclear Cycle Development Institute) and became JAEA (Japan Atomic Energy Agency) on October 1st, 2005. (author)

  16. Epidemiological and virological assessment of influenza activity in Europe, during the 2004-2005 winter.

    NARCIS (Netherlands)

    Meijer, A.; Paget, W.J.; Meerhoff, T.J.; Brown, C.S.; Meuwissen, L.E.; Velden, J. van der

    2006-01-01

    The 2004-2005 influenza season in Europe started in late December 2004 and the first influenza activity occurred in the west and southwest (Spain, United Kingdom and Ireland). Influenza activity then moved gradually east across Europe during January and early February 2005, and from late February

  17. Mumps vaccine failure investigation in Novosibirsk, Russia, 2002-2004.

    Science.gov (United States)

    Atrasheuskaya, A V; Kulak, M V; Rubin, S; Ignatyev, G M

    2007-07-01

    The aims of this study were to estimate the importance of vaccine failure (VF) in cases of mumps during 2002-2004 in the city of Novosibirsk, Western Siberia, Russia, and to genotype the responsible virus strain. Mumps virus-specific RT-PCR testing of saliva was performed for 18 cases of mumps. Sera were tested for IgM and IgG, IgG avidity, and the ability to neutralise a panel of mumps viruses, including the Leningrad-3 mumps vaccine virus. Of the 12 patients for whom vaccination status was positively determined, 11 showed serological evidence of primary VF. Sequence analysis of virus RNA amplified from saliva revealed a genotype C2 virus in 2002, a genotype H2 virus in 2003, and both genotypes in 2004. Although several vaccinated patients were positive for mumps virus IgG at the time of first sampling, only nominal levels of neutralising antibody were detected, and these were effective in neutralising the vaccine strain, but not genotype C and H mumps virus strains. These results suggest that the majority of cases of mumps in vaccinees are caused by primary VF, defined as either a lack of seroconversion or a lack of IgG maturity, as based on avidity testing. The results also support the hypothesis that sera of low neutralising antibody titre have a limited ability to neutralise heterologous mumps virus strains, suggesting that antigenic differences between circulating and mumps vaccine virus strains may play a role in cases of breakthrough infection. Consistent with previous reports, mumps virus genotypes C and H continue to circulate in Novosibirsk.

  18. Vaccinatietoestand Nederland per 1 januari 2005

    NARCIS (Netherlands)

    Abbink F; Oomen PJ; Zwakhals SLN; Melker HE de; Ambler-Huiskes A; Landelijke Vereniging van; Inspectie voor de Gezondheidszorg; CIE

    2006-01-01

    In 2005 national coverage levels for all vaccines used in the Netherlands showed a further increase as compared to 2004. Immunization coverage figures exceed the 95% level and meet the standards provided by the World Health Organisation. The national immunization coverage in the Netherlands has

  19. The extended teamwork 2004/2005 exploratory study. Study plan

    International Nuclear Information System (INIS)

    Skjerve, Ann Britt; Strand, Stine; Skraaning, Gyrd Jr.; Nihlwing, Christer; Helgar, Stein; Olsen, Asle; Kvilesjoe, Hans Oeyvind; Meyer, Geir; Droeivoldsmo, Asgeir; Svengren, Haakan

    2005-09-01

    The report documents the study plan for the Extended Teamwork 2004/2005 exploratory study, which is performed within the Extended Teamwork HRP research program. The purpose of the research program is to generate ideas on how teamwork in nuclear power plants may be affected by the introduction of new operational concepts. The Extended Teamwork 2004/2005 exploratory study contributes with empirical knowledge on the effect of a new operational concept, implying increased automation levels, changed operator roles, redefined competence requirements to the operators, and new technologies to support co-operation, on teamwork. The Extended Teamwork 2004/2005 exploratory study covered occurrences during the early transition phase, i.e., from the time the operators are introduced to the possible future operational environment, to the time they have completed the twelve scenarios comprised by the study. The study assessed how familiarity with operation in the possible future operational environment may affect the extent and quality of co-operation. The report accounts for the motivation for performing the exploratory study, and explains the research question. It describes the theoretical approach, which is based on Co-operation Theory, the human-centered automation approach, and theories on co-operation across distances, and introduces the concept extended teamwork. It also describes the method applied: it provides a detailed description of the possible future operational environment, including requirements with respect to autonomy and authority - both for humans and for automatic agents, and describes the technology applied to support co-operation in the control-room team. In addition, all measurement techniques applied in the study are accounted for (system logs, questionnaires, interviews, etc.). (Author)

  20. Israel Seminar 2004-2005

    CERN Document Server

    Schechtman, Gideon

    2007-01-01

    This collection of original papers related to the Israeli GAFA seminar (on Geometric Aspects of Functional Analysis) during the years 2004-2005 follows the long tradition of the previous volumes that reflect the general trends of the Theory and are a source of inspiration for research. Most of the papers deal with different aspects of the Asymptotic Geometric Analysis, ranging from classical topics in the geometry of convex bodies, to inequalities involving volumes of such bodies or, more generally, log-concave measures, to the study of sections or projections of convex bodies. In many of the papers Probability Theory plays an important role; in some limit laws for measures associated with convex bodies, resembling Central Limit Theorems, are derive and in others probabilistic tools are used extensively. There are also papers on related subjects, including a survey on the behavior of the largest eigenvalue of random matrices and some topics in Number Theory.

  1. Western Pond Turtle Head-starting and Reintroduction; 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Van Leuven, Susan; Allen, Harriet; Slavin, Kate (Washington Department of Fish and Wildlife, Wildlife Management Program, Olympia, WA)

    2005-09-01

    This report covers the results of the western pond turtle head-starting and reintroduction project for the period of October 2004-September 2005. Wild hatchling western pond turtles from the Columbia River Gorge were reared at the Woodland Park and Oregon Zoos in 2004 and 2005 as part of the recovery effort for this Washington State endangered species. The objective of the program is to reduce losses to introduced predators like bullfrogs and largemouth bass by raising the hatchlings to a size where they are too large to be eaten by most of these predators. Thirty-five turtles were placed at the Woodland Park Zoo and 53 at the Oregon Zoo. Of these, 77 head-started juvenile turtles were released at three sites in the Columbia Gorge in 2005. Four were held back to attain more growth in captivity. Eleven were released at the Klickitat ponds, 22 at the Klickitat lake, 39 at the Skamania site, and 5 at Pierce National Wildlife Refuge (NWR). This brought the total number of head-start turtles released since 1991 to 257 for the Klickitat ponds, 136 for the Klickitat lake, 206 for the Skamania pond complex, and 255 at Pierce NWR. In 2005, 34 females from the two Columbia Gorge populations were equipped with transmitters and monitored for nesting activity. Twenty-four nests were located and protected; these produced 90 hatchlings. The hatchlings were collected in September and transported to the Oregon and Woodland Park zoos for rearing in the head-start program. During the 2005 field season trapping effort, 486 western pond turtles were captured in the Columbia Gorge, including 430 previously head-started turtles. These recaptures, together with confirmed nesting by head-start females and visual resightings, indicate the program is succeeding in boosting juvenile recruitment to increase the populations. Records were also collected on 216 individual painted turtles captured in 2005 during trapping efforts at Pierce NWR, to gather baseline information on this native

  2. [Evolution of food supply (apart from school catering) between 2004/2005 and 2009/2010 in middle- and high-schools of Aquitaine, France].

    Science.gov (United States)

    Langevin, C; Carriere, C; Delmas, C; Péchaud, M; Barberger-Gateau, P; Maurice, S; Thibault, H

    2013-02-01

    The aim of this study was to assess the evolution of food supply (apart from school catering) between school years 2004/2005 and 2009/2010, in middle- and high-schools from the Aquitaine region (southwest France), in order to evaluate the impact of actions conducted within the framework and the program Nutrition, Prevention and Health of children and adolescents in Aquitaine (southwest France). Two surveys were carried out among all middle- and high-schools of the Aquitaine region in 2004/2005 (n=536) and 2009/2010 (n=539) within the framework of a regional multidisciplinary public health program "Nutrition, prevention and health of children and teenagers in Aquitaine". For both 2004/2005 and 2009/2010, data were collected using the same questionnaire and dealt with school characteristics and modalities of food supply (apart from school catering). Response rate was 84.1% in 2004/2005 and 79.6% in 2009/2010. The proportion of schools offering food to pupils (apart from school catering) significantly decreased in 5 years (from 80.1% to 50.1%, Pcatering) has also been improved: less sweet and fat food, more bread and fruits. This study shows an overall improvement of food supply apart from school catering (food sale, free food and vending machines) in middle- and high-schools from the Aquitaine region (southwest France) between 2004/2005 and 2009/2010. This improvement is related to the proportion of schools offering food (quantitative improvement), as well as to the composition of food supply (qualitative improvement). These results show an improvement of food supply (apart from school catering), suggesting that actions implemented in the framework of the program "Nutrition, prevention and health of children and adolescents in Aquitaine" may have led to these improvements. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  3. National Fire Plan Research and Development 2004-2005 accomplishment report

    Science.gov (United States)

    Michael W. Hilbruner; Paul Keller

    2007-01-01

    This report highlights accomplishments achieved by USDA Forest Service National Fire Plan Research and Development projects from 2004 through 2005 in four key areas: firefighting, rehabilitation and restoration, hazardous fuels reduction, and community assistance. These highlights illustrate the broad range of knowledge and tools introduced and generated by the...

  4. KURRI progress report 2004. April 2004 - March 2005

    International Nuclear Information System (INIS)

    2005-01-01

    the 3 issues as general researches. This progress report also includes organization, research divisions and laboratories, operation and development of facilities, radiation protection and monitoring, publications from April 2004 to March 2005, meeting, seminars and visiting scientists, and committee members. (J.P.N.)

  5. Estonie 2004-2005 : y a-t-il un pilote dans l'avion? / Antoine Chalvin

    Index Scriptorium Estoniae

    Chalvin, Antoine

    2005-01-01

    Ülevaade sündmustest Eesti poliitikas ja majanduses: valitsuskoalitsiooni lagunemine, sotsiaalpoliitika ning tervishoiu probleemid, Eesti-Vene piirileping, majandusnäitajad, Eesti-Prantsusmaa suhted, EL-iga liitumise mõjud. Tabelid. Lisad: Eesti poliitiliste sündmuste kronoloogia 2004-2005; Valimistulemused alates 2001; Valitsuse koosseis juunis 2005

  6. Progress report on neutron science. April 1, 2004 - March 31, 2005

    International Nuclear Information System (INIS)

    Kurihara, Kazuo; Moriai, Atsushi; Matsuda, Masaaki

    2005-09-01

    This issue summarizes research progress in neutron science at Japan Atomic Energy Research Institute (JAERI) by utilizing the research reactor JRR-3 during the period between April 1, 2004 and March 31, 2005. This report contains highlights in research by 13 neutron research groups at JAERI and 91 summary articles. (author)

  7. The 2005 European e-Business Readiness Index

    OpenAIRE

    Pennoni, Fulvia; Tarantola, Stefano; Latvala, Ari

    2006-01-01

    Assessment of the eEurope 2005 Action Plan Benchmarking Index “E-Business Readiness Composite Indicator” using data collected by National Statistical Institutes and harmonised by Eurostat, using surveys “ICT usage of enterprises”, with reference years 2003 and 2004. This report contains data from 26 countries as collected in 2004 and as reported by Eurostat in June 2005. Performed analyses include obustness analysis, uncertainty and sensitivity analysis for two categories of ICT (Adoption ...

  8. Measles transmission following the tsunami in a population with a high one-dose vaccination coverage, Tamil Nadu, India 20042005

    Directory of Open Access Journals (Sweden)

    Wairgkar Niteen S

    2006-09-01

    Full Text Available Abstract Background On 26 December 2004, a tsunami struck the coast of the state of Tamil Nadu, India, where one-dose measles coverage exceeded 95%. On 29 December, supplemental measles immunization activities targeted children 6 to 60 months of age in affected villages. On 30 December, Cuddalore, a tsunami-affected district in Tamil Nadu reported a cluster of measles cases. We investigated this cluster to estimate the magnitude of the problem and to propose recommendations for control. Methods We received notification of WHO-defined measles cases through stimulated passive surveillance. We collected information regarding date of onset, age, sex, vaccination status and residence. We collected samples for IgM antibodies and genotype studies. We modeled the accumulation of susceptible individuals over the time on the basis of vaccination coverage, vaccine efficacy and birth rate. Results We identified 101 measles cases and detected IgM antibodies against measles virus in eight of 11 sera. Cases were reported from tsunami-affected (n = 71 and unaffected villages (n = 30 with attack rates of 1.3 and 1.7 per 1000, respectively. 42% of cases in tsunami-affected villages had an onset date within 14 days of the tsunami. The median ages of case-patients in tsunami-affected and un-affected areas were 54 months and 60 months respectively (p = 0.471. 36% of cases from tsunami-affected areas were above 60 months of age. Phylogenetic analyses indicated that the sequences of virus belonged to genotype D8 that circulated in Tamil Nadu. Conclusion Measles virus circulated in Cuddalore district following the tsunami, although there was no association between the two events. Transmission despite high one-dose vaccination coverage pointed to the limitations of this vaccination strategy. A second opportunity for measles immunization may help reducing measles mortality and morbidity in such areas. Children from 6 month to 14 years of age must be targeted for

  9. Severe pediatric influenza in California, 2003-2005: implications for immunization recommendations.

    Science.gov (United States)

    Louie, Janice K; Schechter, Robert; Honarmand, Somayeh; Guevara, Hugo F; Shoemaker, Trevor R; Madrigal, Nora Y; Woodfill, Celia J I; Backer, Howard D; Glaser, Carol A

    2006-04-01

    The 2003-2004 influenza season was marked by both the emergence of a new drift "Fujian" strain of influenza A virus and prominent reports of increased influenza-related deaths in children in the absence of baseline data for comparison. In December 2003, the California Department of Health Services initiated surveillance of children who were hospitalized in California with severe influenza in an attempt to measure its impact and to identify additional preventive measures. From December 2003 to May 2005, surveillance of children who were hospitalized in PICUs or dying in the hospital with laboratory evidence of influenza was performed by hospital infection control practitioners and local public health departments using a standardized case definition and reporting form. In the 2003-2004 and 2004-2005 influenza seasons, 125 and 35 cases, respectively, of severe influenza in children were identified in California. The mean and median age of cases were 3.1 years and 1.5 years, with breakdown as follows: AAP) recommendations for immunization, but only 8 had been vaccinated. More than 3 times as many children were reported to be hospitalized in intensive care with influenza in California during the 2003-2004 season compared with the 2004-2005 season. Because children who are younger than 6 months remain at highest risk for severe influenza yet cannot currently be immunized, development and validation of preventive measures for them (eg, maternal immunization, breastfeeding, immunization of young infants and their close contacts) are urgently needed. ACIP's recent recommendation for influenza vaccination of children with conditions that can compromise respiratory function (eg, cognitive dysfunction, spinal cord injuries, seizure disorders, other neuromuscular disorders) is further supported by the frequency of underlying neurologic disease in these cases of severe influenza. A significant proportion of children with severe influenza in California, including children who are

  10. Summaries of research and development activities by using JAERI computer system in FY2004 (April 1, 2004 - March 31, 2005)

    International Nuclear Information System (INIS)

    2005-08-01

    Center for Promotion of Computational Science and Engineering (CCSE) of Japan Atomic Energy Research Institute (JAERI) installed large computer systems including super-computers in order to support research and development activities in JAERI. CCSE operates and manages the computer system and network system. This report presents usage records of the JAERI computer system and the big users' research and development activities by using the computer system in FY2004 (April 1, 2004 - March 31, 2005). (author)

  11. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Clemson University. Sector: Research Institutions

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  12. Atmospheric processes in reaction of Northern Sumatra Earthquake sequence Dec 2004-Apr 2005

    Science.gov (United States)

    Ouzounov, D.; Pulinets, S.; Cervone, G.; Singh, R.; Taylor, P.

    2005-05-01

    This work describes our first results in analyzing data from different and independent sources ûemitted long-wavelength radiation (OLR), surface latent heat flux (SHLF) and GPS Total Electron Content (TEC) collected from ground based (GPS) and satellite TIR (thermal infra-red) data sources (NOAA/AVHRR, MODIS). We found atmosphere and ionosphere anomalies one week prior to both the Sumatra-Andaman Islands earthquake (Dec 26, 2004) and M 8.7 - Northern Sumatra, March 28, 2005. We analyzed 118 days of data from December 1, 2004 through April 1, 2005 for the area (0°-10°,north latitude and 90°-100° east longitude) which included 125 earthquakes with M>5.5. Recent analysis of the continuous OLR from the Earth surface indicates anomalous variations (on top of the atmosphere) prior to a number of medium to large earthquakes. In the case of M 9.0 - Sumatra-Andaman Islands event, compared to the reference fields for the months of December between 2001 and 2004, we found strongly OLR anomalous +80 W/m2 signals (two sigma) along the epicentral area on Dec 21, 2004 five days before the event. In the case of M8.7 March 28, 2005 anomalues signatures over the epicenter appears on March 26 is much weaker (only +20W/m2) and have a different topology. Anomalous values of SHLF associated with M9.0 - Sumatra-Andaman Islands were found on Dec 22, 2005 (SLHF +280Wm2) and less intensity on Mar 23, 2005 (SLHF +180Wm2). Ionospheric variations (GPS/TEC) associated with the Northern Sumatra events were determine by five Regional GPS network stations (COCO, BAKO, NTUS, HYDE and BAST2). For every station time series of the vertical TEC (VTEC) were computed together with correlation with the Dst index. On December 22, four days prior to the M9.0 quake GPS/TEC data reach the monthly maximum for COCO with minor DST activity. For the M 8.7-March 28 event, the increased values of GPS/TEC were observed during four days (March 22-25) in quiet geomagnetic background. Our results need additional

  13. The impact of asthma medication guidelines on asthma controller use and on asthma exacerbation rates comparing 1997-1998 and 2004-2005.

    Science.gov (United States)

    Rank, Matthew A; Liesinger, Juliette T; Ziegenfuss, Jeanette Y; Branda, Megan E; Lim, Kaiser G; Yawn, Barbara P; Shah, Nilay D

    2012-01-01

    The relationship between asthma controller medication use and exacerbation rates over time is unclear at the population level. To estimate the change in asthma controller medication use between 2 time periods as measured by the controller-to-total asthma medication ratio and its association with changes in asthma exacerbation rates between 1997-1998 and 2004-2005. The study design was a cross-sectional population-level comparison between individuals from 1997-1998 and 2004-2005. Study participants were individuals aged 5 to 56 years identified as having asthma in the Medical Expenditure Panel Survey (MEPS). The main outcome measures were a controller-to-total asthma medication ratio greater than 0.5 and asthma exacerbation rates (dispensing of systemic corticosteroid or emergency department visit/hospitalization for asthma) in 1997-1998 compared with 2004-2005. The proportion of individuals with a controller-to-total asthma medication ratio greater than 0.5, when adjusted for other demographic factors, has improved by 16.1% (95% CI: 10.8%, 21.3%) for all individuals from 1997-1998 to 2004-2005. Annual asthma exacerbation rates did not change significantly in any group from 1997-1998 to 2004-2005 (0.27/year to 0.23/year). African American and Hispanic individuals with asthma had higher asthma exacerbation rates and a lower proportion with a controller-to-total asthma medication ratio greater than 0.5 than whites in both 1997-1998 and 2004-2005; however, these differences were not statistically significant. An increase in asthma controller-to-total medication ratio in a sample reflective of the US population was not associated with a decreased asthma exacerbation rate comparing 1997-1998 and 2004-2005. Copyright © 2012 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  14. Injury Profile in Women Shotokan Karate Championships in Iran (2004-2005)

    OpenAIRE

    Halabchi, Farzin; Ziaee, Vahid; Lotfian, Sarah

    2007-01-01

    The aims of this paper were to record injury rates among Iranian women competitive Shotokan karate athletes and propose possible predisposing factors. A prospective recording of the injuries resulting from all matches in 6 consecutive women national Shotokan Karate Championships in all age groups in Iran (season 2004-2005) was performed. Data recorded included demographic characteristics (Age and Weight), athletic background (rank, years of experience, time spent training and previous injurie...

  15. Influenza uitbraken in verpleeghuizen 2004-2005: wat zijn de consequenties voor het komende griepseizoen?

    NARCIS (Netherlands)

    Sande, M. van der; Ruijs, H.; Cools, H.; Meijer, A.; Plas, S. van der; Morroy, G.

    2005-01-01

    Voorafgaand aan het influenzaseizoen 2004/2005 verschenen het LCI draaiboek Explosies van luchtweginfecties in instellingen en de NVVA-richtlijn Influenzapreventie in verpleeghuizen en verzorgingshuizen. Beide werden van theoretische commentaren voorzien in onder andere TvT en het Nederlands

  16. Optimal serotype compositions for Pneumococcal conjugate vaccination under serotype replacement.

    Science.gov (United States)

    Nurhonen, Markku; Auranen, Kari

    2014-02-01

    Pneumococcal conjugate vaccination has proved highly effective in eliminating vaccine-type pneumococcal carriage and disease. However, the potential adverse effects of serotype replacement remain a major concern when implementing routine childhood pneumococcal conjugate vaccination programmes. Applying a concise predictive model, we present a ready-to-use quantitative tool to investigate the implications of serotype replacement on the net effectiveness of vaccination against invasive pneumococcal disease (IPD) and to guide in the selection of optimal vaccine serotype compositions. We utilise pre-vaccination data on pneumococcal carriage and IPD and assume partial or complete elimination of vaccine-type carriage, its replacement by non-vaccine-type carriage, and stable case-to-carrier ratios (probability of IPD per carriage episode). The model predicts that the post-vaccination IPD incidences in Finland for currently available vaccine serotype compositions can eventually decrease among the target age group of children replacement through herd effects, the decrease among the older population is predicted to be much less (20-40%). We introduce a sequential algorithm for the search of optimal serotype compositions and assess the robustness of inferences to uncertainties in data and assumptions about carriage and IPD. The optimal serotype composition depends on the age group of interest and some serotypes may be highly beneficial vaccine types in one age category (e.g. 6B in children), while being disadvantageous in another. The net effectiveness will be improved only if the added serotype has a higher case-to-carrier ratio than the average case-to-carrier ratio of the current non-vaccine types and the degree of improvement in effectiveness depends on the carriage incidence of the serotype. The serotype compositions of currently available pneumococcal vaccines are not optimal and the effectiveness of vaccination in the population at large could be improved by including

  17. Tricomoníase: prevalência no gênero feminino em Sergipe no biênio 2004-2005 Trichomoniasis: prevalence in the female gender in 2004-2005 in Sergipe State, Brazil

    Directory of Open Access Journals (Sweden)

    Mayra Santos Almeida

    2010-06-01

    Full Text Available A tricomoníase é uma protozoose causada pelo Trichomonas vaginalis, que desencadeia uma ampla variedade de manifestações clínicas, podendo estar associada à transmissão do vírus da imunodeficiência humana, câncer cervical, infertilidade, entre outros. No Brasil, a incidência varia entre 20 e 40%. A via primária de transmissão é pelo contato sexual e o diagnóstico laboratorial pode ser realizado através da Reação de Polimerase em Cadeia (PCR, isolamento em meios de cultura e exame do conteúdo vaginal à fresco e/ou corados pelos métodos de Giemsa e Papanicolau. Esse último possui limitações na detecção de patologias consideradas DST, a exemplo da tricomoníase. Esse artigo trata da prevalência de tricomoníase em mulheres usuárias dos laboratórios conveniados ao Ministério da Saúde, na faixa etária de 19 a 44 anos, que foram submetidas ao teste de Papanicolau, em 2004-2005, no Estado de Sergipe. Os resultados revelaram que, em 206.034 usuárias, 7.349 apresentaram tricomoníase, sendo que 3.788 em 2004 e 3.498 em 2005. Observou-se que a prevalência estimada em Sergipe, no biênio estudado, não corrobora com a realidade brasileira, fato esse que pode estar atrelado ao diagnóstico executado.Trichomoniasis is a disease caused by the protozoan Trichomonas vaginalis, which initiates a wide variety of clinical manifestations. It may be associated with human immunodeficiency virus, cervical cancer, infertility and other diseases. Its incidence ranges from 20% up to 40% in Brazil. The primary channel of transmission is by sexual contact and laboratorial diagnostic may be performed by chain polymerase reaction (CPR, culture medium isolation, fresh vaginal content exam and/or colored by Giemsa and Papanicolau methods. The later has limitations in the detection of pathologies considered sexually transmissible, like Thricomoniasis. This work deals with prevalence of Thricomoniasis in users of laboratories associated with the

  18. Severe maternal morbidity for 2004-2005 in the three Dublin maternity hospitals.

    LENUS (Irish Health Repository)

    Murphy, Cliona M

    2012-02-01

    OBJECTIVE: To assess the prevalence and causes of severe maternal morbidity in Dublin over a two year period from 2004 to 2005. STUDY DESIGN: A prospective cohort study from January 2004 to December 2005 was undertaken in the three large maternity hospitals in Dublin, which serve a population of 1.5 million people. All are tertiary referral centres for obstetrics and neonatology and have an annual combined delivery rate of circa 23,000 births. Cases of severe maternal morbidity were identified. A systems based classification was used. The primary cause of maternal morbidity and the number of events experienced per patient was recorded. RESULTS: We identified 158 women who fulfilled the definition for severe maternal morbidity, giving a rate of 3.2 per 1000 maternities. There were two maternal deaths during the time period giving mortality to morbidity ratio of 1:79. The commonest cause of severe morbidity was vascular dysfunction related to obstetric haemorrhage. Eclampsia comprised 15.4% of cases. Intensive care or coronary care admission occurred in 12% of cases. CONCLUSION: The prevalence of severe maternal morbidity in this population is 3.2\\/1000 maternities. Obstetric haemorrhage was the main cause of severe maternal morbidity.

  19. Effect of influenza and pneumococcal vaccines in elderly persons in years of low influenza activity.

    Science.gov (United States)

    Christenson, Brith; Pauksen, Karlis; Sylvan, Staffan P E

    2008-04-28

    The present prospective study was conducted from 2003-2005, among all individuals 65 years and older in Uppsala County, a region with 300 000 inhabitants situated close to the Stockholm urban area.The objective of this study was to assess the preventive effect of influenza and pneumococcal vaccination in reducing hospitalisation and length of hospital stay (LOHS) even during periods of low influenza activity. The specificity of the apparent vaccine associations were evaluated in relation to the influenza seasons. In 2003, the total study population was 41,059, of which 12,907 (31%) received influenza vaccine of these, 4,447 (11%) were administered the pneumococcal vaccine. In 2004, 14,799 (34%) individuals received the influenza vaccine and 8,843 (21%) the pneumococcal vaccine and in 2005 16,926 (39%) individuals were given the influenza vaccine and 12,340 (28%) the pneumococcal vaccine.Our findings indicated that 35% of the vaccinated cohort belonged to a medical risk category (mainly those persons that received the pneumococcal vaccine). Data on hospitalisation and mortality during the 3-year period were obtained from the administrative database of the Uppsala county council. During the influenza seasons, reduction of hospital admissions and significantly shorter in-hospital stay for influenza was observed in the vaccinated cohort (below 80 years of age). For individuals who also had received the pneumococcal vaccine, a significant reduction of hospital admissions and of in-hospital stay was observed for invasive pneumococcal disease and for pneumococcal pneumonia. Effectiveness was observed for cardiac failure even in persons that also had received the pneumococcal vaccine, despite that the pneumococcal vaccinated mainly belonged to a medical risk category. Reduction of death from all causes was observed during the influenza season of 2004, in the 75-84-year old age group and in all age-groups during the influenza season 2005. The present study confirmed the

  20. THE COMPARISON OF INFLUENZA VACCINE EFFICACY ON RESPIRATORY DISEASE AMONG IRANIAN PILGRIMS IN THE 2003 AND 2004 SEASONS

    Directory of Open Access Journals (Sweden)

    M. Razavi

    2005-07-01

    Full Text Available Prolonged cough occurs in a large proportion of the 2 million pilgrims who participate in the annual Hajj in Saudi Arabia. There is no unique cause for pilgrims’ respiratory involvement, but several studies suggest a high incidence of influenza as a cause of the disease. To determine influenza vaccine efficacy against respiratory disease in pilgrims, we conducted two similar cohort studies on 51100 Iranian pilgrims who had participated in the annual Hajj in the years 2003 and 2004. We calculated vaccine efficacy in these two years with the use of “1- odd’s ratio” formula and compared the results. The vaccine efficacy for prevention of influenza like illness in the year 2003 was 51% but the vaccine was not efficient in the year 2004. It was concluded that etiologic agents other than influenza virus should be considered as the cause of respiratory disease in Hajj. Bacterial infections superimposed on chronic respiratory diseases, and allergic or toxic conditions are suggested caourses for more investigation.

  1. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. The Citadel. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  2. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Lander University. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  3. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Winthrop University. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  4. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Medical University of South Carolina. Sector: Research Institutions

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  5. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Columbia. Sector: Research Institutions

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  6. The SPEAR3 Vacuum System - An Analysis of the First Two Years of Operation (2004 and 2005)

    International Nuclear Information System (INIS)

    Armenta, R.

    2005-01-01

    SPEAR 3, a synchrotron radiation source at the Stanford Linear Accelerator Center, has been in operation for the past two years. SPEAR 3 was designed to achieve high beam lifetimes while operating at a higher current level than previously achieved with SPEAR 2. Maintaining high electron beam lifetimes within the ring allows users to perform their experiments with a consistent supply of high current synchrotron radiation. The purpose of this analysis is to evaluate the SPEAR 3 vacuum system's performance during the 2004 and 2005 runs while considering methods to optimize and improve vacuum system conditioning, especially within the pumping system, so that a recommended plan of action can be created for the FY 2006 run. Monitoring the dynamics of the electron beam within the ring can be a difficult task. Pressure data obtained from the gages attached to pumps, temperature data obtained from thermocouples located at various locations around the ring, and beam lifetime projections help to provide some indication of the health of the electron beam, but the true conditions within the beam chamber can only be extrapolated. Data collected from sensors (gauges, thermocouples, etc.) located around the ring can be viewed and extracted from a program created at the Stanford Synchrotron Radiation Laboratory (SSRL) called Historyplot. Manipulation and analysis of data was performed with the commercially available programs Matlab and Excel. The data showed that the beam lifetimes in 2005 were much greater than they were in 2004, but it did not provide a clear indication as to why this occurred. One variable of major importance between the 2004 and 2005 runs is the Titanium Sublimation Pump (TSP) flash frequency (flashing is the process in which Titanium from filaments within the pump is sublimated onto the wall surfaces of the pump, where it removes gas molecules from the system by chemisorption). The data indicated that pressures in 2005 could have been lower, based on a

  7. Energy law - Actual problems 2004/2005; Energierecht - Aktuelle Probleme 2004/2005

    Energy Technology Data Exchange (ETDEWEB)

    Schwintowski, H.P. (ed.)

    2006-07-01

    The book under consideration contains contributions to current problems in the range of energy law which have led to intensive discussions in the years 2005 and 2006. These contributions consider franchise agreements, energy contracting, regional subset distribution systems and long-term supply contracts.

  8. Evaluation of hepatitis A vaccine in post-exposure prophylaxis, The Netherlands, 2004-2012.

    Directory of Open Access Journals (Sweden)

    Jane Whelan

    Full Text Available The secondary attack rate of hepatitis A virus (HAV among contacts of cases is up to 50%. Historically, contacts were offered immunoglobulin (IG, a human derived blood product as post-exposure prophylaxis (PEP. Amid safety concerns about IG, HAV vaccine is increasingly recommended instead. Public health authorities' recommendations differ, particularly for healthy contacts ≥40 years old, where vaccine efficacy data is limited. We evaluated routine use of HAV vaccine as an alternative to immunoglobulin in PEP, in those considered at low risk of severe infection in the Netherlands.Household contacts of acute HAV cases notified in Amsterdam (2004-2012 were invited ≤14 days post-exposure, for baseline anti-HAV testing and PEP according to national guidelines: immunoglobulin if at risk of severe infection, or hepatitis A vaccine if healthy and at low risk (aged 40 years of age. In healthy contacts vaccinated per-protocol ≤8 days post-exposure, RR(ref. ≤15 years of secondary infection in those >40 years was 12.0 (95%CI:1.3-106.7.Timely administration of HAV vaccine in PEP was feasible and the secondary attack rate was low in those 40 years of age and those vulnerable to severe disease.

  9. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Francis Marion University. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  10. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. College of Charleston. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  11. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Coastal Carolina University. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  12. Walla Walla River Fish Passage Operations Program, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Bronson, James P. (Confederated Tribes of the Umatilla Indian Reservation, Department of Natural Resources, Pendleton, OR); Duke, Bill B. (Oregon Department of Fish and Wildlife, Pendleton, OR)

    2006-02-01

    In the late 1990s, the Confederated Tribes of the Umatilla Indian Reservation, Oregon Department of Fish and Wildlife, and Washington Department of Fish and Wildlife, along with many other agencies, began implementing fisheries restoration activities in the Walla Walla Basin. An integral part of these efforts is to alleviate the inadequate fish migration conditions in the basin. The migration concerns are being addressed by removing diversion structures, constructing fish passage facilities, implementing minimum instream flow requirements, and providing trap and haul efforts when needed. The objective of the Walla Walla River Fish Passage Operations Project is to increase the survival of migrating adult and juvenile salmonids in the Walla Walla River basin. The project is responsible for coordinating operation and maintenance of ladders, screen sites, bypasses, trap facilities, and transportation equipment. In addition, the project provides technical input on passage criteria and passage and trapping facility design and operation. Operation of the various passage facilities and passage criteria guidelines are outlined in an annual operations plan that the project develops. During the 2004-2005 project year, there were 590 adult summer steelhead, 31 summer steelhead kelts (Oncorhynchus mykiss), 70 adult bull trout (Salvelinus confluentus); 80 adult and 1 jack spring Chinook (O. tshawytscha) enumerated at the Nursery Bridge Dam fishway video counting window between December 13, 2004, and June 16, 2005. Summer steelhead and spring chinook were observed moving upstream while bull trout were observed moving both upstream and downstream of the facility. In addition, the old ladder trap was operated by ODFW in order to enumerate fish passage. Of the total, 143 adult summer steelhead and 15 summer steelhead kelts were enumerated at the west ladder at Nursery Bridge Dam during the video efforts between February 4 and May 23, 2005. Operation of the Little Walla Walla River

  13. Safety of currently licensed hepatitis B surface antigen vaccines in the United States, Vaccine Adverse Event Reporting System (VAERS), 2005-2015.

    Science.gov (United States)

    Haber, Penina; Moro, Pedro L; Ng, Carmen; Lewis, Paige W; Hibbs, Beth; Schillie, Sarah F; Nelson, Noele P; Li, Rongxia; Stewart, Brock; Cano, Maria V

    2018-01-25

    Currently four recombinant hepatitis B (HepB) vaccines are in use in the United States. HepB vaccines are recommended for infants, children and adults. We assessed adverse events (AEs) following HepB vaccines reported to the Vaccine Adverse Event Reporting System (VAERS), a national spontaneous reporting system. We searched VAERS for reports of AEs following single antigen HepB vaccine and HepB-containing vaccines (either given alone or with other vaccines), from January 2005 - December 2015. We conducted descriptive analyses and performed empirical Bayesian data mining to assess disproportionate reporting. We reviewed serious reports including reports of special interest. VAERS received 20,231 reports following HepB or HepB-containing vaccines: 10,291 (51%) in persons 18 years; for 1485 (7.3%) age was missing. Dizziness and nausea (8.4% each) were the most frequently reported AEs following a single antigen HepB vaccine: fever (23%) and injection site erythema (11%) were most frequent following Hep-containing vaccines. Of the 4444 (22%) reports after single antigen HepB vaccine, 303 (6.8%) were serious, including 45 deaths. Most commonly reported cause of death was Sudden Infant Death Syndrome (197). Most common non-death serious reports following single antigen HepB vaccines among infants aged children aged 1-23 months; infections and infestation (8) among persons age 2-18 years blood and lymphatic systemic disorders; and general disorders and administration site conditions among persons age >18 years. Most common vaccination error following single antigen HepB was incorrect product storage. Review current U.S.-licensed HepB vaccines administered alone or in combination with other vaccines did not reveal new or unexpected safety concerns. Vaccination errors were identified which indicate the need for training and education of providers on HepB vaccine indications and recommendations. Published by Elsevier Ltd.

  14. Effect of influenza and pneumococcal vaccines in elderly persons in years of low influenza activity

    Directory of Open Access Journals (Sweden)

    Sylvan Staffan PE

    2008-04-01

    Full Text Available Abstract Background The present prospective study was conducted from 2003–2005, among all individuals 65 years and older in Uppsala County, a region with 300 000 inhabitants situated close to the Stockholm urban area. The objective of this study was to assess the preventive effect of influenza and pneumococcal vaccination in reducing hospitalisation and length of hospital stay (LOHS even during periods of low influenza activity. The specificity of the apparent vaccine associations were evaluated in relation to the influenza seasons. Results In 2003, the total study population was 41,059, of which 12,907 (31% received influenza vaccine of these, 4,447 (11% were administered the pneumococcal vaccine. In 2004, 14,799 (34% individuals received the influenza vaccine and 8,843 (21% the pneumococcal vaccine and in 2005 16,926 (39% individuals were given the influenza vaccine and 12,340 (28% the pneumococcal vaccine. Our findings indicated that 35% of the vaccinated cohort belonged to a medical risk category (mainly those persons that received the pneumococcal vaccine. Data on hospitalisation and mortality during the 3-year period were obtained from the administrative database of the Uppsala county council. During the influenza seasons, reduction of hospital admissions and significantly shorter in-hospital stay for influenza was observed in the vaccinated cohort (below 80 years of age. For individuals who also had received the pneumococcal vaccine, a significant reduction of hospital admissions and of in-hospital stay was observed for invasive pneumococcal disease and for pneumococcal pneumonia. Effectiveness was observed for cardiac failure even in persons that also had received the pneumococcal vaccine, despite that the pneumococcal vaccinated mainly belonged to a medical risk category. Reduction of death from all causes was observed during the influenza season of 2004, in the 75–84-year old age group and in all age-groups during the influenza

  15. The December 2004-January 2005 floods in the Garden Route region of the Southern Cape, South Africa

    Directory of Open Access Journals (Sweden)

    Johan Tempelhoff

    2009-04-01

    Full Text Available The December 2004-January 2005 floods in the Garden Route region of the Southern Cape in South Africa have had a significant impact on local development and economic activities, tourism products andlocal institutions. This article aims to capture the dynamism between a number of related fields within the context of transdisciplinary research. Qualitative research methods were used to target a representative sample of the affected population. This article considers the history of the flooding events of December 2004/January 2005 along the Garden Route, as well as the manner in which emergency/disaster management personnel responded to the crisis. The effect of the floods on the tourism sector along the Garden Route was researched in general and the effects of the floods on tourists, local residents, and particularly communities in disadvantaged areas were specifically determined. The research reflects on the disaster risk management strategies that were in place at the time of the floods to determine what local authorities could have done to cope with the potential conditions of crisis. The research found that although some tourism products were severely affected, the 2004/2005 floods did not have a significant impact on the number of tourists frequenting the area. In terms of disaster risk management, concerns remain regarding the lack of the following factors: capacity, adequate early warning systems, proper infrastructure maintenance, local institutions, and an in-depth understanding of the disaster risk profile of the area.

  16. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. South Carolina State University. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  17. Ecological Characterization Data for the 2004 Composite Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Downs, Janelle L.; Simmons, Mary A.; Stegen, Jennifer A.; Bunn, Amoret L.; Tiller, Brett L.; Thorsten, Susan L.; Zufelt, Rhett K.

    2004-11-01

    A composite analysis is required by U.S. Department of Energy (DOE) Order 435.1 to ensure public safety through the management of active and planned low-level radioactive waste disposal facilities associated with the Hanford Site. The original Hanford Site Composite Analysis of 1998 must be revised and submitted to DOE Headquarters (DOE-HQ) in 2004 because of revisions to waste site information in the 100, 200, and 300 Areas, updated performance assessments and environmental impact statements (EIS), changes in inventory estimates for key sites and constituents, and a change in the definition of offsite receptors. Beginning in fiscal year (FY) 2003, the DOE Richland Operations Office (DOE-RL) initiated activities, including the development of data packages, to support the 2004 Composite Analysis. This report describes the data compiled in FY 2003 to support ecological site assessment modeling for the 2004 Composite Analysis. This work was conducted as part of the Characterization of Systems Task of the Groundwater Remediation Project (formerly the Groundwater Protection Program) managed by Fluor Hanford, Inc., Richland, Washington. The purpose of this report is to provide summaries of the characterization information and available spatial data on the biological resources and ecological receptors found in the upland, riparian, aquatic, and island habitats on the Hanford Site. These data constitute the reference information used to establish parameters for the ecological risk assessment module of the System Assessment Capability and other assessment activities requiring information on the presence and distribution of biota on the Hanford Site.

  18. Ecological Characterization Data for the 2004 Composite Analysis

    International Nuclear Information System (INIS)

    Downs, Janelle L.; Simmons, Mary A.; Stegen, Amanda A.; Bunn, Amoret L.; Tiller, Brett L.; Thorsten, Susan L.; Zufelt, Rhett K.

    2004-01-01

    A composite analysis is required by U.S. Department of Energy (DOE) Order 435.1 to ensure public safety through the management of active and planned low-level radioactive waste disposal facilities associated with the Hanford Site. The original Hanford Site Composite Analysis of 1998 must be revised and submitted to DOE Headquarters (DOE-HQ) in 2004 because of revisions to waste site information in the 100, 200, and 300 Areas, updated performance assessments and environmental impact statements (EIS), changes in inventory estimates for key sites and constituents, and a change in the definition of offsite receptors. Beginning in fiscal year (FY) 2003, the DOE Richland Operations Office (DOE-RL) initiated activities, including the development of data packages, to support the 2004 Composite Analysis. This report describes the data compiled in FY 2003 to support ecological site assessment modeling for the 2004 Composite Analysis. This work was conducted as part of the Characterization of Systems Task of the Groundwater Remediation Project (formerly the Groundwater Protection Program) managed by Fluor Hanford, Inc., Richland, Washington. The purpose of this report is to provide/SUMmaries of the characterization information and available spatial data on the biological resources and ecological receptors found in the upland, riparian, aquatic, and island habitats on the Hanford Site. These data constitute the reference information used to establish parameters for the ecological risk assessment module of the System Assessment Capability and other assessment activities requiring information on the presence and distribution of biota on the Hanford Site

  19. Report: Audit of Financial Statements As of and for the Years Ended September 30, 2005 and 2004

    Science.gov (United States)

    Report #2006-1-00080, September 28, 2006. CSB's financial statements, as of and for the years ended September 30, 2005 and 2004, are presented fairly, in all material respects, in conformity with accounting principles generally accepted in the USA.

  20. Influenza vaccine effectiveness among adult patients in a University of Lyon hospital (2004-2009).

    Science.gov (United States)

    Amour, Sélilah; Voirin, Nicolas; Regis, Corinne; Bouscambert-Duchamp, Maude; Comte, Brigitte; Coppéré, Brigitte; Pires-Cronenberger, Silene; Lina, Bruno; Vanhems, Philippe

    2012-01-20

    The aim of this study was to estimate influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza among hospitalized patients. A case-control investigation was based on the prospective surveillance of influenza-like illness (ILI) during five flu seasons. We compared influenza-positive cases and influenza-negative controls. Unadjusted overall IVE was 62% (95% confidence interval 24% to 81%). We found that IVE was lower during the 2004-05 flu season (11%; 95% CI -232% to 76%) when the vaccine and circulating viruses were mismatched. Expansion of the study to other hospitals could provide IVE estimates earlier in the season, for different age groups and emerging virus strains. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Upstate. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  2. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Aiken. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  3. 2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Beaufort. Sector: Four-Year Colleges and Universities

    Science.gov (United States)

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

  4. Neurological adverse events temporally associated to mass vaccination against yellow fever in Juiz de Fora, Brazil, 1999-2005.

    Science.gov (United States)

    Fernandes, Guilherme Côrtes; Camacho, Luiz Antonio Bastos; Sá Carvalho, Marilia; Batista, Maristela; de Almeida, Sonia Maria Rodrigues

    2007-04-20

    The identification of adverse events following immunization (AEFI) and their prompt investigation are important to allow a timely and scientifically based response to the users of immunization services. This article presents an analysis of notified AEFI cases between 1999 and 2005 and their temporal association with 2001 yellow fever vaccination campaign, AEFI notification attributed to yellow fever vaccination rose from 0.06 to 1.32 per 100,000 vaccinees in Brazil, between 1998 and 2000. During the 2001 yellow fever mass vaccination campaign held in Juiz de Fora, Brazil, 12 cases of aseptic meningitis were temporally associated to yellow fever vaccination, but clinical and laboratory data were not available to confirm nor deny causality. Epidemiological studies associated to enhanced surveillance and standardized protocols should take advantage of public health interventions like mass vaccination campaigns and implementation of new vaccination strategies in order to assess and investigate vaccine safety.

  5. Stagnation in body mass index in Denmark from 1997/1998 to 2004/2005, but with geographical diversity

    DEFF Research Database (Denmark)

    Svendstrup, Mathilde; Knudsen, Nils Jacob; Jørgensen, Torben

    2011-01-01

    INTRODUCTION: We analyzed the trend in body mass index (BMI) as well as in the prevalence of overweight and obesity among Danish adults, mainly women, from 1997/1998 to 2004/2005 and evaluated any regional differences. MATERIAL AND METHODS: Data were drawn from two cross-sectional population...

  6. Decline of Neurologic Varicella Complications in Children During the First Seven Years After Introduction of Universal Varicella Vaccination in Germany, 2005-2011.

    Science.gov (United States)

    Streng, Andrea; Grote, Veit; Rack-Hoch, Anita; Liese, Johannes G

    2017-01-01

    Universal varicella vaccination for 1-year-old children was introduced in Germany in 2004. We investigated changes in the incidence and type of varicella-associated neurologic complications in children during the first 7 years after universal vaccination recommendation. A surveillance study was conducted based on patients linear trend across years was assessed by Poisson regression models. Of a total of 1263 varicella-associated pediatric hospitalizations, 228 children (18.1%) had neurologic complications (median age 4 years, interquartile range 2-7; 56% male). The most frequent neurologic complications were febrile convulsion (32.0% of 228 children, median age 3.0 years), varicella encephalitis or meningitis (28.9%; median age 4.5 years), syncope (13.2%; median age 7.0 years) and cerebral convulsion (11.0%; median age 4.0 years). Other complications included ataxia (3.1%), facial nerve palsy (2.6%) and cerebral vasculitis/infarction (1.8%). Neurologic complications showed a continuous decrease between 2005 and 2011, from an incidence of 2.8 (95% confidence interval: 2.1-3.6) per 100,000 children <17 years of age to 1.2 (95% confidence interval: 0.7-2.1; P < 0.001). In particular, a marked decline was observed among children up to 7 years of age, mainly because of a decrease in the number of febrile convulsions and encephalitis or meningitis. The incidence of varicella-associated neurologic complications in children decreased approximately by 60% during the first 7 years following the recommendation for universal vaccination.

  7. A study to analyze IAEA planning of 2004-2005 programme and to establish cooperation directions with the IAEA

    International Nuclear Information System (INIS)

    Oh, K. B.; Lee, K. S.; Lee, B. W.; Ko, H. S.; Ryu, J. S.; Lee, T. J.; Kim, M. R.

    2003-07-01

    The objective of this study is to utilize the IAEA effectively through reflecting Korea's opinion fully for the planning of the Agency's 20042005 Programme. This study first analyzed the current status of the IAEA Programme and Budget and reviewed the issues relevant to Korea. Second, this study assessed the IAEA 20042005 Programme and drew up Korea's opinion for it. The official document including the opinions was submitted to the Secretariat. In reviewing the Programme, this study considered the strengths of Korea related to the Programme. Also some projects and CRPs, which can be lead by Korea, were proposed. The IAEA 20042005 Programme reflected well the technical and social changes and its structure seems to be proper. The budget was proposed to be increased over 10%, violating the zero-real growth principle. This seems to be inevitable considering the increase of safeguards activities. However, there should be prepared some measures to avoid rapid increase of the burdens of the Member States. In the process of the planning of the IAEA 20042005 Programme, the following points should be emphasized. First, SMR activities should be given a high priority considering the high interests of developing countries and be set up as a separate project as in the 2002∼2003 Programme. Second, more budget should be allocated for Project A.4.04(Support for demonstration of nuclear seawater desalination), considering the highest priority of the project in Program A. Third, it's better to change the title of Subprogram C.3 to 'Nuclear knowledge Preservation' to stick to the original rationale of the subprogram. There is a need for further activities such as establishing and implementing the concept of international nuclear school based on the result of the feasibility study done in 2002∼2003. Fourth, further activities needs to be added to the Project D.2.03 for the efficient conversion to high density, low enriched uranium in Member States; for instance, review

  8. Piimatootmine : [1999-2004 Eestis] / Matti Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Matti, 1947-

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 11-13. Põllumajanduse kogutoodangust moodustas piimatootmine 2004. a. hinnanguliselt 29%. Diagrammid

  9. WHO informal consultation on scientific basis for regulatory evaluation of candidate human vaccines from plants, Geneva, Switzerland, 24-25 January 2005.

    NARCIS (Netherlands)

    Laan, Jan Willem van der; Minor, Philip; Mahoney, Richard; Arntzen, Charles; Shin, Jinho; Wood, David

    2006-01-01

    In January 2005, WHO convened a meeting of leading experts in plant-derived vaccines and experts from regulatory authorities for an informal discussion on the state-of-the-art and to analyse whether specific guidance might be needed for plant-derived vaccines that is not yet provided by regulatory

  10. Escapement and Productivity of Spring Chinook and Summer Steelhead in the John Day River Basin, Technical Report 2004-2005.

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Wayne

    2007-04-01

    The objectives are: (1) Estimate number and distribution of spring Chinook salmon Oncorhynchus tshawytscha redds and spawners in the John Day River subbasin; and (2) Estimate smolt-to-adult survival rates (SAR) and out-migrant abundance for spring Chinook and summer steelhead O. mykiss and life history characteristics of summer steelhead. Spawning ground surveys for spring (stream-type) Chinook salmon were conducted in four main spawning areas (Mainstem, Middle Fork, North Fork, and Granite Creek System) and seven minor spawning areas (South Fork, Camas Creek, Desolation Creek, Trail Creek, Deardorff Creek, Clear Creek, and Big Creek) in the John Day River basin during August and September of 2005. Census surveys included 298.2 river kilometers (88.2 rkm within index, 192.4 rkm additional within census, and 17.6 rkm within random survey areas) of spawning habitat. We observed 902 redds and 701 carcasses including 227 redds in the Mainstem, 178 redds in the Middle Fork, 420 redds in the North Fork, 62 redds in the Granite Creek System, and 15 redds in Desolation Creek. Age composition of carcasses sampled for the entire basin was 1.6% age 3, 91.2% age 4, and 7.1% age 5. The sex ratio was 57.4% female and 42.6% male. Significantly more females than males were observed in the Granite Creek System. During 2005, 82.3% of female carcasses sampled had released all of their eggs. Significantly more pre-spawn mortalities were observed in Granite Creek. Nine (1.3%) of 701 carcasses were of hatchery origin. Of 298 carcasses examined, 4.0% were positive for the presence of lesions. A significantly higher incidence of gill lesions was found in the Granite Creek System when compared to the rest of the basin. Of 114 kidney samples tested, two (1.8%) had clinical BKD levels. Both infected fish were age-4 females in the Middle Fork. All samples tested for IHNV were negative. To estimate spring Chinook and summer steelhead smolt-to-adult survival (SAR) we PIT tagged 5,138 juvenile

  11. Fracture Resistance Evaluation of Fibre Reinforced Brittle Matrix Composites

    Czech Academy of Sciences Publication Activity Database

    Dlouhý, Ivo; Chlup, Zdeněk

    2005-01-01

    Roč. 290, - (2005), s. 167-174 ISSN 1013-9826. [Fractography of Advanced Ceramic s /2./. Stará Lesná, 03.10.2004-06.10.2004] R&D Projects: GA AV ČR(CZ) IAA2041003; GA ČR(CZ) GA101/02/0683 Keywords : fibre-reinforced ceramic s * glass matrix composites * chevron notch Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 0.224, year: 2005

  12. A study to analyze IAEA planning of 2004-2005 programme and to establish cooperation directions with the IAEA

    Energy Technology Data Exchange (ETDEWEB)

    Oh, K. B.; Lee, K. S.; Lee, B. W.; Ko, H. S.; Ryu, J. S.; Lee, T. J.; Kim, M. R

    2003-07-01

    The objective of this study is to utilize the IAEA effectively through reflecting Korea's opinion fully for the planning of the Agency's 2004{approx}2005 Programme. This study first analyzed the current status of the IAEA Programme and Budget and reviewed the issues relevant to Korea. Second, this study assessed the IAEA 2004{approx}2005 Programme and drew up Korea's opinion for it. The official document including the opinions was submitted to the Secretariat. In reviewing the Programme, this study considered the strengths of Korea related to the Programme. Also some projects and CRPs, which can be lead by Korea, were proposed. The IAEA 2004{approx}2005 Programme reflected well the technical and social changes and its structure seems to be proper. The budget was proposed to be increased over 10%, violating the zero-real growth principle. This seems to be inevitable considering the increase of safeguards activities. However, there should be prepared some measures to avoid rapid increase of the burdens of the Member States. In the process of the planning of the IAEA 2004{approx}2005 Programme, the following points should be emphasized. First, SMR activities should be given a high priority considering the high interests of developing countries and be set up as a separate project as in the 2002{approx}2003 Programme. Second, more budget should be allocated for Project A.4.04(Support for demonstration of nuclear seawater desalination), considering the highest priority of the project in Program A. Third, it's better to change the title of Subprogram C.3 to 'Nuclear knowledge Preservation' to stick to the original rationale of the subprogram. There is a need for further activities such as establishing and implementing the concept of international nuclear school based on the result of the feasibility study done in 2002{approx}2003. Fourth, further activities needs to be added to the Project D.2.03 for the efficient conversion to high density

  13. Fracture behaviour of brittle (glass) matrix composites

    Czech Academy of Sciences Publication Activity Database

    Dlouhý, Ivo; Chlup, Zdeněk; Boccaccini, A. R.

    2005-01-01

    Roč. 482, - (2005), s. 115-122 ISSN 0255-5476. [International Conference on Materials Structure and Micromechanics of Fracture /4./. Brno, 23.06.2004-25.06.2004] R&D Projects: GA AV ČR(CZ) IAA2041003; GA ČR(CZ) GA101/02/0683 Institutional research plan: CEZ:AV0Z2041904 Keywords : Ceramic matrix composites * fracture toughness * toughening effects Subject RIV: JH - Ceramic s, Fire-Resistant Materials and Glass Impact factor: 0.399, year: 2005

  14. Antimicrobial resistence of Shigella species isolated during 2004 and 2005 from selected sites in Zimbabwe.

    Science.gov (United States)

    Ndlovu, N; Tarupiwa, A; Mudzori, J T

    2006-01-01

    To determine the predominant serotype and antibiotic sensitivity pattern of Shigella isolates during 2004 and 2005 in Zimbabwe. Cross sectional study. National Microbiology Reference Laboratory (NMRL), Harare, Zimbabwe. 259 clinical isolates of Shigella species isolated during 2004 and 2005 in Zimbabwe were studied. These samples had been referred to the NMRL for further testing. Serotype and antibiotic sensitivity pattern of Shigella species. Of the 259 clinical isolates of Shigella tested the following species were serotyped; 141 (54.4%) were S. flexneri; 70 (27%) S. sonnei; 38 (14.7%) S. dysenteriae and 10 (3.9%) S. boydii. About 4% of all Shigella isolates tested showed full sensitivity to commonly used antibiotics, 20.8% were resistant to one antibiotic only while 75.3% were resistant to at least two antibiotics. The most common resistance among Shigella species was to cotrimoxazole (89%), tetracycline (73%), ampicillin (49%) and chloramphenicol (41%). High susceptibility among Shigella species was observed to nalidixic acid (86%), ciprofloxacin (99%) and ceftazidine (99%). There was a low drug resistance of Shigella species to nalidixic acid, a drug of choice in Zimbabwe, except among Shigella dysenteriae type 1 strains. Continuous monitoring of the susceptibility patterns of Shigella species is important in order to detect the emergence of drug resistance and to update guidelines for antibiotic treatment in shigellosis.

  15. [The late media emergency of smallpox vaccine, news coverage of Spanish press (1999-2004)].

    Science.gov (United States)

    Martínez-Martínez, Pedro Javier; Tuells, José; Colmenar-Jarillo, Gema

    2015-06-01

    Discussions on the need for smallpox virus preservation in 1999 focused attention on an eradicated disease 20 years ago. Smallpox was replaced as a potential candidate to be used as a bioterrorist weapon because of the international alarm scenario produced after the 11/9 events in USA. The reactivation of a vaccine which remained forgotten was the direct consequence. The initial target groups were the security forces of America. Spain was also among the countries that were interested in acquiring the smallpox vaccine. The aim of this study is to analyze the considerable media coverage of smallpox obtained in our country. Systematic review of published news in the four largest national daily newspapers (ABC, El Mundo, El País and La Vanguardia) for the period 1999-2004 of the Dow Jones Factiva document database. "Smallpox" were used as a key word. From the obtained data, a qualitative and quantitative analysis was done. 416 reviews were analyzed; the newspaper El Mundo was the most interested in these news (158 citations, 37.98%). Most of the news were published in 2003 (152, 36.5%) The year with more news about smallpox (2003) coincides with the purchase of vaccines in Spain. The type of messages in the news was highly changeable over this six-year period. Those related to "politics and diplomacy", "epidemiological risk", "bioterrorism" and "vaccine" were predominant. The alarm raised around the smallpox vaccination was a media phenomenon due to political strategy issues rather than a real public health problem.

  16. Maaturism : [2004 Eestis] / Kristine Hindriks

    Index Scriptorium Estoniae

    Hindriks, Kristine

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 106-109. Tunnustatud maamajutusettevõtteid oli 2004. a. 546 ehk 10% enam kui möödunud aastal, neist kodumajutus ja puhkemajad moodustavad 55%, puhkekülad ning külalistemajad 29%, hostelid, hotellid, motellid kokku 16%. Diagrammid

  17. Feeding biology of the introduced fish roi, and its impact on Hawaiian reef fishes, January 2004 and January 2005, (NODC Accession 0002172)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Feeding biology of the introduced fish roi (Cephalopholis argus), and its impact on Hawaiian reef fishes and fisheries between January 2004 and January 2005. Roi...

  18. Internet cigarette purchasing among 9th grade students in western New York: 2000-2001 vs. 2004-2005.

    Science.gov (United States)

    Fix, Brian V; Zambon, Margaret; Higbee, Cheryl; Cummings, K Michael; Alford, Terry; Hyland, Andrew

    2006-09-01

    To assess trends and correlates of youth cigarette purchasing behavior on the Internet. In 2000-2001, Roswell Park Cancer Institute conducted a survey asking 7,019 ninth grade students in Erie and Niagara Counties in New York State about their tobacco use and purchasing habits, including use of the Internet to buy cigarettes. The 2004-2005 survey is a replication of the 2000-2001 survey. Both surveys used an anonymous, self-administered questionnaire survey. These data were combined in order to examine trends in youth smoking behavior. Students surveyed in 2004-2005 were 2.6 times more likely (95% CI: 1.5, 4.6) to have purchased cigarettes over the Internet in the 30 days prior to the survey than those surveyed in 2001 (5.2% to 1.6%); however, the intention to use the Internet as a cigarette source in the future did not change between survey periods. Youth online cigarette purchasing has increased but intention to use the Internet to purchase cigarettes in the future has remained the same, suggesting that this trend may be reaching a plateau. Recent public efforts to reduce online cigarette sales will need to be evaluated in order to determine which policy or combination of policies are most effective.

  19. River Data Package for the 2004 Composite Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rakowski, Cynthia L.; Guensch, Gregory R.; Patton, Gregory W.

    2004-08-01

    Beginning in fiscal year 2003, the DOE Richland Operations Office initiated activities, including the development of data packages, to support the 2004 Composite Analysis. The river data package provides calculations of flow and transport in the Columbia River system. This document presents the data assembled to run the river module components for the section of the Columbia River from Vernita Bridge to the confluence with the Yakima River.

  20. Alkoholi tootmine ja turg : [2002-2004] / Katrin Karolin

    Index Scriptorium Estoniae

    Karolin, Katrin

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 45-47. 2004. a. 9 kuu alkoholi jaekäive ulatus 2,2 mld kroonini, mis on 13% suurem kui eelmise aasta samal perioodil. Tabelid: Alkohoolsete jookide tootmine Eestis (9 kuud 2002-2004); Alkoholi tarbimine elanike hinnangute alusel

  1. Coseismic and post-seismic signatures of the Sumatra 2004 December and 2005 March earthquakes in GRACE satellite gravity

    Science.gov (United States)

    Panet, I.; Mikhailov, V.; Diament, M.; Pollitz, F.; King, G.; de Viron, O.; Holschneider, M.; Biancale, R.; Lemoine, J.-M.

    2007-01-01

    The GRACE satellite mission has been measuring the Earth's gravity field and its temporal variations since 2002 April. Although these variations are mainly due to mass transfer within the geofluid envelops, they also result from mass displacements associated with phenomena including glacial isostatic adjustment and earthquakes. However, these last contributions are difficult to isolate because of the presence of noise and of geofluid signals, and because of GRACE's coarse spatial resolution (>400 km half-wavelength). In this paper, we show that a wavelet analysis on the sphere helps to retrieve earthquake signatures from GRACE geoid products. Using a wavelet analysis of GRACE geoids products, we show that the geoid variations caused by the 2004 December (Mw = 9.2) and 2005 March (Mw = 8.7) Sumatra earthquakes can be detected. At GRACE resolution, the 2004 December earthquake produced a strong coseismic decrease of the gravity field in the Andaman Sea, followed by relaxation in the area affected by both the Andaman 2004 and the Nias 2005 earthquakes. We find two characteristic timescales for the relaxation, with a fast variation occurring in the vicinity of the Central Andaman ridge. We discuss our coseismic observations in terms of density changes of crustal and upper-mantle rocks, and of the vertical displacements in the Andaman Sea. We interpret the post-seismic signal in terms of the viscoelastic response of the Earth's mantle. The transient component of the relaxation may indicate the presence of hot, viscous material beneath the active Central Andaman Basin. ?? 2007 The Authors Journal compilation ?? 2007 RAS.

  2. British Columbia Utilities Commission service plan 2004/2005 - 2006/2007

    International Nuclear Information System (INIS)

    2004-01-01

    The mandate of the British Columbia Utilities Commission (BCUC) is to ensure that customers receive safe, reliable and non-discriminatory energy services at fair rates from the utilities. It must also ensure that the shareholders of the utilities have a reasonable opportunity to earn a fair return on the invested capital. This report describes the following six key areas that underlie the Commission's strategic planning for the next 3 years: (1) regulation of automobile insurance, (2) energy policy implementation, (3) natural gas commodity costs, (4) commercial unbundling and customer choice, (5) energy trade, and (6) benchmarking. The report also describes strategic issues with reference to priorities, shifts and risk management. Alignment with the government's strategic plan was also reviewed. The financial outlook for 2003/04 and 2006/07 shows that the Commission intends to fully recover costs from the utilities it regulates. The budget for 2003/04 has increased somewhat from the forecasted amount for the same period reported in the previous year's service plan. This is due to an expanded mandate. Forecast values for the 2004/05 and 2005/06 planning periods have decreased slightly compared to the previous year's plan. tabs., figs

  3. Physical, chemical, and biological data collected during two research cruises in the Ross Sea, Antarctica from December 2004 to January 2005 and October to November 2005 for Ross Sea Sulfur Dynamics study (NODC Accession 0117322)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains transect data from two research cruises to the Ross Sea, Antarctica, aboard the RV Nathaniel B. Palmer (NBP) in December 2004 to January 2005...

  4. 2005 sales: organic growth of 3.7%; Chiffre d'affaires 2005: croissance organique de 3,7%

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-01-15

    The AREVA group's sales revenue for the year rose to 10,125 million euros, compared with 9,821 million euros in 2004, adjusted for the Connectors division, representing 3.1% growth in terms of reported data. Organic growth was up 3.7% for 2005. The nuclear divisions posted organic growth of 4.6%, signaled by: - growth in the Front End division (+5.2%) linked to the favorable price effect for uranium supplies and to climbing volumes in all of the division's businesses; - new projects in Finland, France and China and strong performance in services, the growth driver for the Reactors and Services division (+10.8%); - the drop in sales for the Back End division (-2.9%) following the 2004 completion of the support contract with Japanese customer JNFL; a contract extension for 2006 and 2007 was signed in late 2005. The Transmission and Distribution division recorded organic growth of 2.0%. The 5.8% increase in the second half of 2005 over 2004 offsets the downturn in the first half of 2005 compared with the same period in 2004, when a one-time peak was observed. New orders rose by 13.1% like-for-like over the period, resulting in a large backlog at the end of 2005. For the fourth quarter of 2005, the group recorded growth of 2.4% in reported data compared with the fourth quarter of 2004, and organic growth of 1.8%. Foreign exchange rate differences had a positive impact of 69 million euros.

  5. Main Achievements 2003-2004 - Carbon-carbon Composites

    International Nuclear Information System (INIS)

    2005-01-01

    There is a long tradition at IFJ PAN of building light mechanical structures from composite materials for detectors in high energy physics experiments. With time, this activity has also evolved into purely technological developments and into applications outside particle physics. A special device for long-term testing of such structures has also been designed and manufactured at IFJ PAN in 2004. The apparatus makes it possible to determine the fatigue properties of disc samples. This work was performed in collaboration with the Department of Biomaterials, Faculty of Materials, Engineering and Ceramics, of the AGH in Cracow

  6. Detection and genetic characterization of norovirus strains circulating among infants and children with acute gastroenteritis in Japan during 2004-2005.

    Science.gov (United States)

    Phan, Tung Gia; Takanashi, Sayaka; Kaneshi, Kunio; Ueda, Yuichi; Nakaya, Shigekazu; Nishimura, Shuichi; Sugita, Kumiko; Nishimura, Tadashi; Yamamoto, Atsuko; Yagyu, Fumihiro; Okitsu, Shoko; Maneekarn, Niwat; Ushijima, Hiroshi

    2006-01-01

    A total of 752 fecal specimens collected during the period of July 2004 to June 2005 from infants and children with acute gastroenteritis from four different regions (Maizuru, Tokyo, Sapporo, and Osaka) of Japan were tested for the presence of norovirus by RT-PCR. It was found that 139 (18.5%) fecal specimens were positive for norovirus. Norovirus infection was detected almost all year round with the highest prevalence in January. Norovirus GII was the most predominant genogroup (98.6%; 137 of 139). The genotypes detected in this study were GI/1, GII/1, GII/3, GII/4, and GII/6. Of these, NoV GII/4 (known as the Lordsdale virus cluster) was re-emerging and became the leading genotype (77.7%). Meanwhile, the incidence of NoV GII/3 (known as the Arg320 virus cluster) has dropped rapidly, accounting for only 15.8%. Another interesting feature of the study was the identification of Picton03/AU-like recombinant NoV for the first time in Japan. Based on the genetic analysis, it was interesting to note that NoV GII/4 in 2004-2005 made a distinct cluster in comparison to other NoV GII/4 circulating in 2002-2003 and 2003-2004. Of note, "new recombinant variant designated GIIb" within NoV GII/3, which was first detected in Saga City, Japan in 2003-2004 in only one case, had increased, spreading widely in Japan and representing 45.5% (10 of 22). Further epidemiological studies should be conducted to determine whether this new recombinant variant strain will be dominant in Japan in the coming year.

  7. [Emergence of invasive pneumococcal disease caused by non-vaccine serotypes in the era of the 7-valent conjugate vaccine].

    Science.gov (United States)

    González Martínez, F; Navarro Gómez, M L; Saavedra Lozano, J; Santos Sebastián, M M; Rodríguez Fernández, R; González Sanchéz, M; Cercenado Mansilla, E; Hernández-Sampelayo Matos, T

    2014-03-01

    There has been an increased incidence in invasive pneumococcal disease (IPD) produced by non-vaccine serotype (NVS) of Streptococcus pneumoniae after the introduction of PCV7. Our objective was to describe the epidemiological, clinical and microbiological characteristics of IPD caused by NVS in a tertiary hospital in Madrid. Retrospective (1998-2004) and prospective (2005-2009) study evaluating IPD caused by NVS in children. The study was divided into three periods: P1 (1998-2001) when PCV7 was not commercialized; P2 (2002-2005) with 40% vaccine coverage among children; and P3 (2006-2009) when the vaccine was added to the Childhood Immunization Schedule in Madrid. We analyzed 155 cases of IPD. One hundred and fifty of these isolates were serotyped (100 were NVS). There was an increase in the prevalence of IPD from P1 (31%) to P2 (54%) and P3 (91%). The most relevant emerging serotypes were 19A, 7F, 1, 5, 3 and 15C. The most significant clinical syndromes produced by some specific serotypes were as follows: lower respiratory tract infection (LRTI) by serotypes 1, 3, 5 and 15C; LRTI, primary bacteremia and meningitis by serotype 19A; and primary bacteremia by serotype 7F (66%). The large majority (83.8%) of NVS were sensitive to penicillin. There has been an increased prevalence of IPD caused by NVS since the introduction of PCV7. These changes should prompt the introduction of new pneumococcal vaccines, which include most of the NVS, in the childhood immunization calendar to prevent IPD in children. Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  8. Erametsandus : [2002-2004] / Monika Lublo

    Index Scriptorium Estoniae

    Lublo, Monika, 1976-

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 112-118. 2001. a põllumajandusloenduse andmeil kuulus metsamaast 91% füüsilistele ja 9% juriidilistele isikutele. Tabelid

  9. Evaluation of live attenuated S79 mumps vaccine effectiveness in mumps outbreaks: a matched case-control study.

    Science.gov (United States)

    Fu, Chuan-xi; Nie, Jun; Liang, Jian-hua; Wang, Ming

    2009-02-05

    Mumps virus infection is a potentially serious viral infection of childhood and early adulthood. In China, live attenuated S(79) mumps vaccine has been licensed for pediatric use since 1990. The objective of this study was to determine the effectiveness of live attenuated S(79) mumps vaccine against clinical mumps in outbreaks. Cases were selected from mumps outbreaks in schools in Guangzhou between 2004 and 2005. Each case was matched by gender, age and classroom. Vaccination information was obtained from Children's EPI Administrative Computerized System. Vaccine effectiveness (VE) was calculated for 1 or 2 doses of S(79) vaccine with 95% confidence intervals (CI). One hundred and ninety-four cases and 194 controls were enrolled into the study. VE of the S(79) mumps vaccine for 1 dose versus 0 confer protection 80.4% (95% CI, 60.0%-90.4%) and VEs against mumps in outbreaks for 1 dose of mumps vaccine are similar among those children aged 4-9 years and aged over 10 years old. The live attenuated S(79) mumps vaccine can be effective in preventing clinical mumps outbreaks.

  10. Status of coastal forests of the Northern Sumatra in 2005 (after 2004’s tsunami catastrophe

    Directory of Open Access Journals (Sweden)

    ONRIZAL

    2016-04-01

    Full Text Available Abstract. Onrizal, Mansor M. 2015. Status of coastal forests of the Northern Sumatra in 2005 (after 2004’s tsunami catastrophe. Biodiversitas 17: 44-54. The first intensive ecological study of coastal vegetation including mangrove, littoral and peat swamp forests after the 2004 tsunami catastrophe in Northern Sumatra was conducted from January to December 2005 where 16 sampling sites along 2960km coastline in Northern Sumatra were selected. In each site, one quadrat of 100 m x 100 m was established and divided into 10 m x 10 m subplots where all standing trees of ≥ 2 cm diameter at breast height (DBH were identified to species level and measured. Overall 54,871 standing trees were recorded in 16 sites comprising 84 species in 65 genera and 37 families. Mangrove trees Rhizophora apiculata and R. mucronata were widely distributed and are dominant in most of the sampling sites. This indicated that these species have stronger resilient compared to other species. The highest value of Shannon-Wiener index of species and Evenness index of species was 3.03 and 0.85, respectively. It means that some sites were rich in biodiversity which harbors various species of plants. Subsequently, undisturbed coastal forests including mangroves, littoral forests and peat swamp forests characterized by dense stands, mixed species and structures play an important role in coastal protection against tsunami. Therefore, the coastal vegetation is needed to conserve the biodiversity and to maintain the production capacity as part of sustainable and longlasting vegetation bioshield.

  11. Theses defended at Tunis Faculty of Medecine from 2004 to 2005: Scientific become and predictive factors of publications.

    Science.gov (United States)

    Elloumi, Hela; Bouarrouj, Reem; Chadli Debbiche, Ashraf; Mrabet, Ali; Dziri, Chadli

    2017-04-01

    Several theses are supported, every year, in the Faculty of Medicine of Tunis but their scientific become is this day unknown. The most part of specialities have not bibliometric data. This work had for objectives to study the still unknown future of theses of Tunis Faculty of Medecine during 2004-2005, in terms of publication in indexed reviews and to determine the predictive factors of their publication. This was a descriptive bibliometric study of theses supported at the Tunis Faculty of Medicine between January 1st, 2004 and december 31st, 2005. The data collected concerned :number of theses, involved specialities, discipline, type of theses, type of study, number of studied cases (theses. The publication of the theses has been sought in engines "Medline" and "scopus. Predictive factors for publication were sought. Six hundred and thirteen theses were supported, including 57.7% belonged to the medical disciplines. The attributed mention was "very honorable with the congratulations of the jury" in 71,0% of cases and "very honorable with the congratulations of the jury and the proposal at the price of thesis " in 24,0% of the cases. Thirteen comma four pourcent (13.4%) was the rate of publication. These theses were published when the attributed mention was "very honorable with the congratulations of the jury and the proposal at the price of thesis "(p=0.05), when the discipline was community (p theses-teacher- year was lower than 1 in 70% of cases and the index of becoming theses varied from 0 and 18.7 across all disciplines. The thesis were published in half of the cases in the the review"La Tunisie Médicale". The median of citation was 2 [0-66 citations]. The publication was found thanks to the name of the student which appeared as author in 61.0% of the theses. The student was first author in 12 cases (24.5%). The rate of publication of theses of Tunis Faculty of Medecine during 2004-2005 aws little raised by 13.4%. This rate should be considered as a basic

  12. International Atomic Energy Agency publications. Publications catalogue 2005 including full details of publications published in 2003-2004 and forthcoming in 2005 and a stocklist of publications published in 2001-2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-03-15

    This Publications Catalogue lists all sales publications of the IAEA published in 2003, 2004 and forthcoming in 2005. Most IAEA publications are issued in English, some are also available in Arabic, Chinese, French, Russian or Spanish. This is indicated at the bottom of the book entry. A complete listing of all IAEA priced publications is available on the IAEA's web site: http://www.iaea.org/books.

  13. International Atomic Energy Agency publications. Publications catalogue 2005 including full details of publications published in 2003-2004 and forthcoming in 2005 and a stocklist of publications published in 2001-2002

    International Nuclear Information System (INIS)

    2005-03-01

    This Publications Catalogue lists all sales publications of the IAEA published in 2003, 2004 and forthcoming in 2005. Most IAEA publications are issued in English, some are also available in Arabic, Chinese, French, Russian or Spanish. This is indicated at the bottom of the book entry. A complete listing of all IAEA priced publications is available on the IAEA's web site: http://www.iaea.org/books

  14. De essentie van de daling in het aantal verkeersdoden : ontwikkelingen in 2004 en 2005, en nieuwe prognoses voor 2010 en 2020.

    NARCIS (Netherlands)

    Stipdonk, H.L. Aarts, L.T. Schoon, C.C. & Wesemann, P.

    2006-01-01

    The essence of the decrease in the number of road deaths; Developments in 2004 and 2005, and new prognoses for 2010 and 2020. During the last 15 to 20 years there was a 2.5% annual decrease in the number of road deaths. This decrease is attributed to all kinds of important, gradual improvements of

  15. Serological response to influenza vaccination among children vaccinated for multiple influenza seasons.

    Directory of Open Access Journals (Sweden)

    Sajjad Rafiq

    Full Text Available To evaluate if, among children aged 3 to 15 years, influenza vaccination for multiple seasons affects the proportion sero-protected.Participants were 131 healthy children aged 3-15 years. Participants were vaccinated with trivalent inactivated seasonal influenza vaccine (TIV over the 2005-06, 2006-07 and 2007-8 seasons. Number of seasons vaccinated were categorized as one (2007-08; two (2007-08 and 2006-07 or 2007-08 and 2005-06 or three (2005-06, 2006-07, and 2007-08. Pre- and post-vaccination sera were collected four weeks apart. Antibody titres were determined by hemagglutination inhibition (HAI assay using antigens to A/Solomon Islands/03/06 (H1N1, A/Wisconsin/67/05 (H3N2 and B/Malaysia/2506/04. The proportions sero-protected were compared by number of seasons vaccinated using cut-points for seroprotection of 1:40 vs. 1:320. The proportions of children sero-protected against H1N1 and H3N2 was high (>85% regardless of number of seasons vaccinated and regardless of cut-point for seroprotection. For B Malaysia there was no change in proportions sero-protected by number of seasons vaccinated; however the proportions protected were lower than for H1N1 and H3N2, and there was a lower proportion sero-protected when the higher, compared to lower, cut-point was used for sero-protection.The proportion of children sero-protected is not affected by number of seasons vaccinated.

  16. 2005 sales: organic growth of 3.7%

    International Nuclear Information System (INIS)

    2006-01-01

    The AREVA group's sales revenue for the year rose to 10,125 million euros, compared with 9,821 million euros in 2004, adjusted for the Connectors division, representing 3.1% growth in terms of reported data. Organic growth was up 3.7% for 2005. The nuclear divisions posted organic growth of 4.6%, signaled by: - growth in the Front End division (+5.2%) linked to the favorable price effect for uranium supplies and to climbing volumes in all of the division's businesses; - new projects in Finland, France and China and strong performance in services, the growth driver for the Reactors and Services division (+10.8%); - the drop in sales for the Back End division (-2.9%) following the 2004 completion of the support contract with Japanese customer JNFL; a contract extension for 2006 and 2007 was signed in late 2005. The Transmission and Distribution division recorded organic growth of 2.0%. The 5.8% increase in the second half of 2005 over 2004 offsets the downturn in the first half of 2005 compared with the same period in 2004, when a one-time peak was observed. New orders rose by 13.1% like-for-like over the period, resulting in a large backlog at the end of 2005. For the fourth quarter of 2005, the group recorded growth of 2.4% in reported data compared with the fourth quarter of 2004, and organic growth of 1.8%. Foreign exchange rate differences had a positive impact of 69 million euros

  17. Evaluation of Fall Chinook and Chum Salmon Spawning below Bonneville Dam; 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    van der Naald, Wayne; Duff, Cameron; Friesen, Thomas A. (Oregon Department of Fish and Wildlife, Clackamas, OR)

    2006-02-01

    Pacific salmon Oncorhynchus spp. populations have declined over the last century due to a variety of human impacts. Chum salmon O. keta populations in the Columbia River have remained severely depressed for the past several decades, while upriver bright (URB) fall Chinook salmon O. tschawytscha populations have maintained relatively healthy levels. For the past seven years we have collected data on adult spawning and juvenile emergence and outmigration of URB fall Chinook and chum salmon populations in the Ives and Pierce islands complex below Bonneville Dam. In 2004, we estimated 1,733 fall Chinook salmon and 336 chum salmon spawned in our study area. Fall Chinook salmon spawning peaked 19 November with 337 redds and chum salmon spawning peaked 3 December with 148 redds. Biological characteristics continue to suggest chum salmon in our study area are similar to nearby stocks in Hardy and Hamilton creeks, and Chinook salmon we observe are similar to upriver bright stocks. Temperature data indicated that 2004 brood URB fall Chinook salmon emergence began on 6 January and ended 27 May 2005, with peak emergence occurring 12 March. Chum salmon emergence began 4 February and continued through 2 May 2005, with peak emergence occurring on 21 March. Between 13 January and 28 June, we sampled 28,984 juvenile Chinook salmon and 1,909 juvenile chum salmon. We also released 32,642 fin-marked and coded-wire tagged juvenile fall Chinook salmon to assess survival. The peak catch of juvenile fall Chinook salmon occurred on 18 April. Our results suggested that the majority of fall Chinook salmon outmigrate during late May and early June, at 70-80 mm fork length (FL). The peak catch of juvenile chum salmon occurred 25 March. Juvenile chum salmon appeared to outmigrate at 40-55 mm FL. Outmigration of chum salmon peaked in March but extended into April and May.

  18. A comparative analysis of influenza vaccination programs.

    Directory of Open Access Journals (Sweden)

    Shweta Bansal

    2006-10-01

    Full Text Available BACKGROUND: The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States have sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus. METHODS AND FINDINGS: We present a comparative analysis of two classes of suggested vaccination strategies: mortality-based strategies that target high-risk populations and morbidity-based strategies that target high-prevalence populations. Applying the methods of contact network epidemiology to a model of disease transmission in a large urban population, we assume that vaccine supplies are limited and then evaluate the efficacy of these strategies across a wide range of viral transmission rates and for two different age-specific mortality distributions. We find that the optimal strategy depends critically on the viral transmission level (reproductive rate of the virus: morbidity-based strategies outperform mortality-based strategies for moderately transmissible strains, while the reverse is true for highly transmissible strains. These results hold for a range of mortality rates reported for prior influenza epidemics and pandemics. Furthermore, we show that vaccination delays and multiple introductions of disease into the community have a more detrimental impact on morbidity-based strategies than mortality-based strategies. CONCLUSIONS: If public health officials have reasonable estimates of the viral transmission rate and the frequency of new introductions into the community prior to an outbreak, then these methods can guide the design of optimal vaccination priorities. When such information is unreliable or not available, as is often the case, this study recommends mortality-based vaccination priorities.

  19. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal, Annual Progress Report, October 1, 2004 through September 30, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce G

    2006-03-01

    Since 1998, The Pennsylvania State University (PSU) has been successfully operating the Consortium for Premium Carbon Products from Coal (CPCPC), which is a vehicle for industry-driven research on the promotion, development, and transfer of innovative technology on premium carbon produces from coal to the U.S. industry. The CPCPC is an initiative being led by PSU, its co-charter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provides the base funding for the program, with PSU responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity has continued under the present cooperative agreement, No. DE-FC26-03NT41874, which started October 1, 2003. The objective of the second agreement is to continue the successful operation of the CPCPC. The CPCPC has enjoyed tremendous success with its organizational structure, that includes PSU and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC is its industry-led council that selects proposals submitted by CPCPC members to ensure CPCPC target areas have strong industrial support. A second contract was executed with DOE NETL starting in October 2003 to continue the activities of CPCPC. An annual funding meeting was held in October 2003 and the council selected ten projects for funding. Base funding for the projects is provided by NETL with matching funds from industry. Subcontracts were let from Penn State to the subcontractors on March 1, 2004. Nine of the ten projects have been completed and the final reports for these 2004 projects are attached. An annual funding meeting was held in November 2004 and the council

  20. Institute of Nuclear physics of Lyon - IPNL, Activity Report 2004-2005

    International Nuclear Information System (INIS)

    2006-01-01

    The Institute of Nuclear physics of Lyon (IPNL) is under the joint supervision of the Claude Bernard University of Lyon (UCBL) and the National Institute of Nuclear and particle physics (IN2P3) of the CNRS (National Centre for Scientific Research). The laboratory studies the properties and interactions of sub-atomic particles. Its activities are largely experimental, with groups involved in a wide range of national and international collaborations concerning particle and astro-particle physics, nuclear matter and the interactions of ions and cluster with matter. In addition, the Institute has important interdisciplinary and applied research activities related to: detectors R and D, confinement of radioactive waste, bio-medical imaging, measurement of environmental levels of radioactive elements. This document presents the activity of the Centre during the 2004-2005 years: 1 - Research topics: Quarks and Leptons; Astro-particles; Hadronic and nuclear matter; Theoretical physics; trans-disciplinary activities; 2 - Technical support to experiments (electronics, Computers, Mechanics, Instrumentation, Radiation protection, Accelerators, LABRADOR metrology service, Administration); 3 - Transverse activities (Training, Science and society, Communication, Documentation); 4 - Scientific life (publications, seminars, conferences, exhibitions, PhDs..); 5 - Manpower (Permanent training, Staff)

  1. Nuclear and high-energy physics laboratory - LPNHE. Activity report 2004-2005

    International Nuclear Information System (INIS)

    Debu, Pascal; Bassler, Ursula; Boratav, Murat; Lacour, Didier; Lebbolo, Herve; Cossin, Isabelle; Mathy, Jean-Yves

    2006-01-01

    The LPNHE is a joint research unit (UMR 7585) of the National Institute of Nuclear Physics and Particle Physics (IN2P3), Institute of the National Centre for Scientific Research (CNRS), UPMC and Paris Diderot Paris 7. It hosts several research teams and technical services (computers, electronics, mechanical), and two support services (administration, logistics). The laboratory is engaged in several major experimental programs pursued in the framework of international collaborations with very large research facilities around the world, centers of particle accelerators and observatories. The research programs cover current issues in particle physics, astro-particle and cosmology. This report presents the activities of the laboratory during the years 2004-2005: 1 - Forewords; 2 - Scientific activities: Physics with accelerators (LHC, Tevatron, CP Violation, future linear electron collider, Neutrino beams); Physics without accelerators (Cosmology and supernovae, high-energy gamma astronomy, extreme energy cosmic radiation, theoretical physics, physics-biology interface); 3 - Technical and administrative activities (electronics, computers, mechanics departments, Administration, health and safety, radiation protection); 4 - Laboratory life (Teaching, training, internships and PhDs); 5 - Internal activities (seminars, meetings..); 6 - External activities (Public information, relations with the industry, valorisation..); 7 - List of publications; 8 - Appendixes: organigram, staff

  2. Põllumajandussektori tulude areng 2004. aastal (EAA alusel) / Kristel Maidre

    Index Scriptorium Estoniae

    Maidre, Kristel, 1978-

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 87-89. Esialgsetel andmetel kujunes põllumajanduse majandusharu toodanguks koos toetustega 2004. a 7,3 mld krooni, millest tootetoetused taime- ja loomakasvatusele moodustasid 5,4% (392,9 mln krooni). Tabel

  3. Environmental and effluent monitoring at ANSTO sites, 2004-2005

    International Nuclear Information System (INIS)

    Hoffmann, Emmy L.; Loosz, Tom; Ferris, John M.; Harrison, Jennifer J.

    2005-01-01

    This report presents the results of ANSTO's environmental and effluent monitoring at the Lucas Heights Science and Technology Centre (LHSTC) and the National Medical Cyclotron (NMC) sites, from July 2004 to June 2005. Effective doses to the critical group of members of the public potentially affected by routine airborne emissions from the LHSTC were less than 0.005 mSv/year. This estimated maximum potential dose is less than 24% of the ANSTO ALARA objective of 0.02 mSv/year, and much lower than the public dose limit of 1 mSv/year that is recommended by the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA). The effective doses to the critical group of members of the public potentially exposed to routine liquid effluent releases from the LHSTC have been realistically estimated as a quarter (or less) of the estimated doses to the critical group for airborne releases. The levels of tritium detected in groundwater and stormwater at the LHSTC were less than those set out in the Australian Drinking Water Guidelines. The airborne and liquid effluent emissions from the NMC were below both the ARPANSA-approved notification levels and Sydney Water limits for acceptance of trade wastewater to sewer. Results of environmental monitoring at both ANSTO sites confirm that the facilities continue to be operated well within regulatory limits. ANSTO's routine operations at the LHSTC and NMC make only a very small addition to the natural background radiation dose of ∼1.5 mSv/year experienced by members of the Australian public

  4. Influenza vaccine effectiveness among healthcare workers in comparison to hospitalized patients: A 2004-2009 case-test, negative-control, prospective study

    Science.gov (United States)

    Vanhems, P; Baghdadi, Y; Roche, S; Bénet, T; Regis, C; Lina, B; Robert, O; Voirin, N; Ecochard, R; Amour, S

    2016-01-01

    The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from participating units (n = 24) were included, and vaccination status was characterized by interview. A total of 150 HCW presented ILI; 130 (87%) were female, 27 (18%) were positive for influenza, and 42 (28%) were vaccinated. Adjusted VE was 89% (95% CI 39 to 98). Among patients, adjusted VE was 42% (95% CI −39 to 76). The difference of VE (VEhcw - VEpat) was 46.15% (95% CI 2.41 to 144). The VE ratio (VEhcw / VEpat) was 2.09 (95% CI −1.60 to 134.17). Influenza VE differed between HCW and patients when the flu season was taken into account. This finding confirms the major impact of host determinants on influenza VE. PMID:26327520

  5. "Telling our stories": Print media interpretations of Moscow lesbians' life stories in 2004 and 2005.

    Science.gov (United States)

    Bingham, Natasha

    2017-01-02

    This article analyzes print media interviews of Moscow lesbians in Moskovsky Komsomolets in 2004 and 2005 using qualitative content analysis. The qualitative content analysis shows recurring and consistent themes: (1) the stereotypes lesbians face; (2) public negativity toward same-sex relations and the impact on their families; (3) the expectations of heterosexuality and all that that entails; (4) the existence of lesbian-only spaces in Russia and the importance of those spaces; and (5) the complexities of navigating motherhood, previous heterosexual relationships, and current partnerships. Analysis of print media representations of female same-sex sexuality in a period of economic prosperity, popular culture visibility, and before restrictive laws were passed that suppress homosexuality adds to the previous literature on lesbianism in Russia.

  6. Wind River Watershed Restoration 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, Patrick J.; Jezorek, Ian G. [U.S. Geological Survey

    2008-11-10

    During 2004, researchers from U.S. Geological Survey's Columbia River Research Laboratory (USGS-CRRL) collected temperature, flow, and habitat data to characterize physical habitat condition and variation within and among tributaries and mainstem sections in the Wind River subbasin. Juvenile salmonid population surveys were conducted within select study areas throughout the subbasin. We expanded our survey coverage of the mainstem Wind River to a reach in the vicinity of Carson National Fish Hatchery to assess effects of non-indigenous Chinook on native steelhead. These efforts add to a database of habitat and fish data collected in the Wind River since 1996. This research contributes to the Wind River Restoration Project, which includes active stream habitat restoration and monitoring of adult and juvenile steelhead populations. We maintained a network of 32 thermographs in the Wind River subbasin during 2004. Additionally, Underwood Conservation District provided us with data from seven thermographs that they maintained during 2004. Thermograph data are identifying areas with chronic high water temperatures and stream sections where high rates of warming are occurring. During 2004, water temperatures at 26 thermograph sites exceeded the 16 C limit for surface waters set by the Washington Department of Ecology. Water temperatures exceeded 20 C at five sites in the Trout Creek watershed. Our thermograph dataset includes information from as early as 1996 at some sites and has become a valuable long-term dataset, which will be crucial in determining bioenergetic relationships with habitat and life-histories. We have monitored salmonid populations throughout the Wind River subbasin by electrofishing and snorkeling. We electrofished four stream sections for population estimates during 2004. In these sections, and others where we simply collected fish without a population estimate, we tagged juvenile steelhead and Chinook salmon with Passive Integrated Transponder

  7. 2005 Guidelines for Advancement and Promotion

    CERN Multimedia

    Human Resources Department

    2005-01-01

    1. General The Director-General has now fixed the guidelines and schedule for the 2005 annual advancement review in the framework of the Merit Advancement and Promotion Scheme (MAPS). Procedures are set out in Administrative Circular N° 6 (Rev. 5). Decisions will be made, where possible, by 1 July 2005 except for career path changes for staff in Career Paths A to D which will be made by 31 October 2005 and applied retroactively to 1 July 2005. Departments are invited to comply strictly with the target date for the completion of the annual interviews which this year has been fixed at 15 March 2005. Exceptions due to particular circumstances (e.g. long-term absences) must be documented. As already announced in Weekly Bulletin 48/2004-22.11.2004 and further explained in Weekly Bulletin 3/2005-17.1.2005, the annual appraisal report should be completed using the electronic version in the EDH system. 2. Budget guidelines Within the annual advancement budget, the guideline allocations have been defi...

  8. Annual summary of vital statistics: 2005.

    Science.gov (United States)

    Hamilton, Brady E; Miniño, Arialdi M; Martin, Joyce A; Kochanek, Kenneth D; Strobino, Donna M; Guyer, Bernard

    2007-02-01

    The general fertility rate in 2005 was 66.7 births per 1000 women aged 15 to 44 years, the highest level since 1993. The birth rate for teen mothers (aged 15 to 19 years) declined by 2% between 2004 and 2005, falling to 40.4 births per 1000 women, the lowest ever recorded in the 65 years for which there are consistent data. The birth rates for women > or = 30 years of age rose in 2005 to levels not seen in almost 40 years. Childbearing by unmarried women also increased to historic record levels for the United States in 2005. The cesarean-delivery rate rose by 4% in 2005 to 30.2% of all births, another record high. The preterm birth rate continued to rise (to 12.7% in 2005), as did the rate for low birth weight births (8.2%). The infant mortality rate was 6.79 infant deaths per 1000 live births in 2004, not statistically different from the rate in 2003. Pronounced differences in infant mortality rates by race and Hispanic origin continue, with non-Hispanic black newborns more than twice as likely as non-Hispanic white and Hispanic infants to die within 1 year of birth. The expectation of life at birth reached a record high in 2004 of 77.8 years for all gender and race groups combined. Death rates in the United States continued to decline, with death rates decreasing for 9 of the 15 leading causes. The crude death rate for children aged 1 to 19 years did not decrease significantly between 2003 and 2004. Of the 10 leading causes of death for 2004 in this age group, only the rates for influenza and pneumonia showed a significant decrease. The death rates increased for intentional self-harm (suicide), whereas rates for other causes did not change significantly for children. A large proportion of childhood deaths continue to occur as a result of preventable injuries.

  9. Liha tootmine : [2000-2004 Eestis liikide kaupa, s.h. ka kitseliha] / Matti Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Matti, 1947-

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 20-22. 2004. a. vähenes sealihatoodang 3%, lamba- ja kitseliha toodang 25%.Veise- ja linnuliha tootmine kasvas kubki 5%. Tabel: Lihatoodang aastatel 2000-2004

  10. Genetically modified tumour vaccines

    Czech Academy of Sciences Publication Activity Database

    Bubeník, Jan

    2005-01-01

    Roč. 3, Suppl. 1 (2005), S7 ISSN 1214-021X. [Cells VI - Biological Days /18./. 24.10.2005-26.10.2005, České Budějovice] Institutional research plan: CEZ:AV0Z50520514 Keywords : tumour vaccines * HPV16 Subject RIV: EC - Immunology

  11. Powernext Day-AheadTM statistics April 30, 2005

    International Nuclear Information System (INIS)

    2005-04-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the April 30, 2005 update of Powernext Day-Ahead TM statistics: traded volumes and average prices from November 2001 to April 2005, monthly overview from April 2004 to April 2005 (volumes, prices and price spreads), weekly overview from January to April 2005, daily and hourly overview and market resilience for April 2005, power consumption in March and April 2005 (average consumption, average forecasted consumption and average price on Powernext Day-Ahead TM ), power consumption on the French hub from January to April 2005 and Powernext Day-Ahead TM prices, transfer capacities in April 2005 (daily capacity allocations for France-Germany, France-Switzerland and France-Spain, daily and monthly capacity allocations for France-Belgium, auction on the France-UK Interconnector, daily and yearly capacity allocation for France-Italy), temperature variations in France from November 2004 to April 2005 and average prices on Powernext Day-Ahead TM , and balancing mechanism for March-April 2005 (half-hourly imbalance settlement prices). (J.S.)

  12. Kala töötlemine : [andmeid aastatest 1995-2004] / Maarja Purik

    Index Scriptorium Estoniae

    Purik, Maarja

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 49-52. Kalatöötlemise osatähtsus toiduainetööstuses moodustas 2004. a. 11,9% ja ekspordis 24,9%. Tabelid. Diagrammid

  13. Mahepõllumajandus : [1999-2004, ka ökomärgist] / Peeter Prass

    Index Scriptorium Estoniae

    Prass, Peeter

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk.43-45. Hinnanguliselt moodustas 2004. a. mahepõllundusega hõivatud maa üldisest põllumajandusmaast alla 5%. Piimalehmadest olid maheloomad veidi üle 2%. Diagrammid

  14. Transmission of the L-Zagreb mumps vaccine virus, Croatia, 2005-2008.

    Science.gov (United States)

    Kaic, B; Gjenero-Margan, I; Aleraj, B; Ljubin-Sternak, S; Vilibic-Cavlek, T; Kilvain, S; Pavic, I; Stojanovic, D; Ilic, A

    2008-04-17

    We report on three cases of symptomatic transmission of the L-Zagreb mumps vaccine virus from three vaccinated children to five adult contacts. The five contact cases were parents of the vaccinated children and presented with parotitis and in one case also with aseptic meningitis. The etiology of the contacts' illness was determined by viral culture, genomic sequencing, serology and epidemiological linking. Two of the vaccinated children developed vaccine associated parotitis as an adverse event three weeks following immunization. Symptoms in contact cases developed five to seven weeks after the vaccination of the children. The five contact cases, as well as the three children with adverse events recovered completely. The children had been vaccinated with MMR vaccine produced by the Institute of Immunology Zagreb, each of them with a different lot. One of the possible explanations for these adverse events is that the very low levels of wild mumps virus circulation in the last decade, combined with waning immunity in those who received one dose of vaccine or suffered from mumps in childhood, resulted in susceptible young adults and that this unique epidemiological situation allows us to detect horizontal transmission of mumps vaccine virus.

  15. The results of screening examinations of breast cancer conducted from 2004 to 2005 in Sierpc poviat

    International Nuclear Information System (INIS)

    Nowicki, A.; Milecka, A.

    2007-01-01

    Background: Breast cancer is one of the most common malignant neoplasms among women in Poland. 11733 new cases were registered in 2003. Well organized screening examinations are the most effective method of fighting against breast cancer. Aim of study: The main objective of this work was a preliminary analysis of a prophylactic examination programme for breast cancer in Sierpc district performed by the Independent Unit of Public Health Care Centres in Sierpc during the period of 2004 to 2005. Material and methods: The research was performed based on retrospective analysis of files obtained from the Department of Radiology of the Independent Unit of Public Health Care Centres in Sierpc. Prophylactic examination for detection of breast cancer includes physical examination of the breast as well as mammography. Results: The research includes 1291 women, most of them at age 50-55 years (57.1 years on average). City residents represent the biggest group of women. Nearly half of women had their first menstruation at the age of 14 to 15 years. The last menstruation occurred at age between 46 and 50 years old most frequently. The average number of labours was 2.3 and 2.5 during the analyzed period. The first labour occurred most frequently in women at the age of 21 to 25 years old. Most of the women never took previously and still do not take hormonal medicines. 80% of women have done breast self examination but over half of them (60.8%) did it occasionally. Breast examination done by a gynaecologist was performed in 22% of women during the last year. Breast cancer did not occur among family members in most of the analyzed women. Breast pain was the most frequent complaint. Over half of women (64.6%) previously underwent mammography. The biggest group among them (31.1%) includes women who had mammography between 2003 and 2004. Adipose glandular breast texture was detected in near half of women (43.5%). The result of mammography was normal in most analyzed women (87.1%). A

  16. Appointment with Climate 2005; Rendez-vous climat 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document takes stock on the situation one year after the Climate Plan decided by the government in July 2004. It provides the allocutions of politicians occurred during the 14 and 15 November 2005 and a synthesis of the main questions and problems discussed during these two days. (A.L.B.)

  17. White Sturgeon Mitigation and Restoration in the Columbia and Snake Rivers Upstream from Bonneville Dam; 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Rien, Thomas A.; Hughes, Michele L.; Kern, J. Chris (Oregon Department of Fish and Wildlife, Clackamas, OR)

    2006-03-01

    We report on our progress from April 2004 through March 2005 on determining the effects of mitigative measures on productivity of white sturgeon populations in the Columbia River downstream from McNary Dam, and on determining the status and habitat requirements of white sturgeon populations in the Columbia and Snake rivers upstream from McNary Dam. This is a multi-year study with many objectives requiring more than one year to complete; therefore, findings from a given year may be part of more significant findings yet to be reported.

  18. [Measles in Poland in 2004].

    Science.gov (United States)

    Czarkowski, Mirosław P; Kondej, Barbara; Paweł, Stefanoff

    2006-01-01

    In Poland 11 measles cases were registered in 2004 (0.03 per 100,000 population), of which 3 were cases imported from Chechnya. Of 8 local cases, 3 cases occurred in unvaccinated persons, 2 in persons vaccinated with one dose and 3 in vaccinated with two doses of measles vaccine (administered at the age of 13-15 months and 7 years). The most affected age groups were 1-year old children (0.29 per 100,000 population) and 6-year olds (0.25). Out of 11 reported cases 2 were hospitalized. There were no deaths attributed to measles. Poland participates in the WHO Measles Elimination Strategy. Presently, the most important is the maintenance of a sensitive and timely surveillance of measles and measles-compatible cases, with serologic testing of one suspect case per 100,000 population. The performance of the surveillance system was insufficient with only 44 measles-compatible cases reported in 2004 (12% of expected reports). Serologic confirmation of cases was also insufficient, with 5 cases confirmed in WHO accredited laboratory. These results indicate the need to maintain the high immunisation coverage and improve measles surveillance system.

  19. The LNG Industry - 2004

    International Nuclear Information System (INIS)

    2005-04-01

    First estimates for the marketed production of natural gas in 2004 show a rise of about 2 % over 2003. The share of LNG in the gas trade accounts for 21.9 % of the total. This annual report presents: 1 - LNG contracts and trade, 2 - Contracts concluded in 2004, 3 - LNG imports - Sources of imports - Quantities received in 2005 by the importing countries from the exporting countries, 4 - LNG tankers, 5 - 21 Ships delivered in 2004, 6 - Tanker distribution (at the end of 2004), 7 - Liquefaction plants, 8 - re-gasification plants, 9 - Long-term and medium-term contracts in force in 2004, 10 - Spot and short term quantities received in 2004 by the importing countries from the exporting countries, 11 - Sea transportation routes, 12 - Liquefaction plants (table), 13 - re-gasification plants (table), 14 - Delivery date of the LNG tankers

  20. Institute of Nuclear Physics of Orsay - IPNO. Activity report 2004-2005

    International Nuclear Information System (INIS)

    2006-01-01

    The Institute of Nuclear Physics of Orsay (IPN Orsay) is undertaking nuclear physics research that is centered on the nature of matter and its ultimate constituents. By the nature of its scientific activities, the IPN is at the heart of a wide range of international collaborations. IPN Orsay is a unit of both the CNRS (National Centre of Scientific Research) and of the Paris-Sud University. It plays a vital role in experiments being carried out by wide-ranging collaborations at major experimental facilities most notably in Europe, the United States and Japan. Its own facilities allows the IPN to carry out fundamental theoretical and experimental research studies in nuclear physics, astro-particle physics, radiochemistry but also in pluri-disciplinary activities. This document presents the activity of the Institute during the 2004-2005 years: 1 - Scientific activities: Nuclear structure; Hadronic physics and matter; Astro-particles; Theoretical physics; Hot nuclei; Energy and Environment; Particle Matter Interactions; Physics-Biology-Medicine Interfaces in Neurobiology, Oncology and Genomic; Knowledge dissemination and communication; 2 - Technical activities: General and technical departments; Accelerators Division; 3 - Appendixes: Publications, Proceedings, Conferences, workshops, collaboration meetings, Internal seminars, External seminars, Heavy ions seminars, Theoretical seminars, Radiochemistry seminars, Seminars of general interest, Scientific events, Schools and lectures, Thesis, accreditations to supervise research, Books and works, 'Journal club', Staff, Visitors

  1. Changes in hepatitis A and B vaccination rates in adult patients with chronic liver diseases and diabetes in the U.S. population.

    Science.gov (United States)

    Younossi, Zobair M; Stepanova, Maria

    2011-10-01

    Professional societies recommend hepatitis A and hepatitis B immunization for individuals with chronic liver disease (CLD), but the degree of implementation is unknown. Data were obtained from the National Health and Nutrition Examination Surveys (NHANES) conducted in 1999-2008. For the entire study population and for those with CLD and diabetes, we determined the rates and independent predictors of history of hepatitis A and hepatitis B (HepA and HepB) vaccinations, of their effectiveness, and of seroprevalence of hepatitis A antibody and anti-HB surface antibody. In total, 24,871 participants from NHANES were included: 14,886 (1999-2004) and 9,985 (2005-2008). Of these individuals, 14.0% had CLD and 8.6% had diabetes. During the study period, HepA vaccination in CLD increased from 13.3% ± 1.0% to 20.0% ± 1.5%, HepB vaccination increased from 23.4% ± 1.2% to 32.1% ± 1.5%. Of subtypes of CLD, HepA vaccination rates increased only in nonalcoholic fatty liver disease (NAFLD), whereas HepB vaccination increased for patients with hepatitis C and nonalcoholic fatty liver disease. In the diabetic cohort, HepA vaccination rates increased from 9.3% ± 1.1% to 15.4% ± 1.7% and HepB rates increased from 15.2% ± 1.5% to 22.4% ± 1.7%. All changes were similar to those observed in the general population. The quality measure (QM) for HepA in the general population decreased from 44.4% ± 1.2% in 1999-2004 to 41.7% ± 1.9% in 2005-2008, and similar changes were noted for all subcohorts. On the other hand, QM for HepB increased from 31.7% ± 0.9% to 40.7% ± 1.0% in the population, whereas no changes in QM were noted in any diagnostic cohort except for NAFLD. Although vaccination rates in CLD and diabetic cohorts are increasing, they remain low. Given the public health implications of acute hepatitis A and hepatitis B in patients with CLD, better implementation of the vaccination recommendations for these populations is warranted. Copyright © 2011 American Association for

  2. Multi-point ground-based ULF magnetic field observations in Europe during seismic active periods in 2004 and 2005

    Directory of Open Access Journals (Sweden)

    G. Prattes

    2008-05-01

    Full Text Available We present the results of ground-based Ultra Low Frequency (ULF magnetic field measurements observed from June to August 2004 during the Bovec earthquake on 12 July 2004. Further we give information about the seismic activity in the local observatory region for an extended time span 2004 and 2005. ULF magnetic field data are provided by the South European Geomagnetic Array (SEGMA where the experience and heritage from the CHInese MAGnetometer (CHIMAG fluxgate magnetometer comes to application. The intensities of the horizontal H and vertical Z magnetic field and the polarization ratio R of the vertical and horizontal magnetic field intensity are analyzed taking into consideration three SEGMA observatories located at different close distances and directions from the earthquake epicenter. We observed a significant increase of high polarization ratios during strong seismic activity at the observatory nearest to the Bovec earthquake epicenter. Apart from indirect ionospheric effects electromagnetic noise could be emitted in the lithosphere due to tectonic effects in the earthquake focus region causing anomalies of the vertical magnetic field intensity. Assuming that the measured vertical magnetic field intensities are of lithospheric origin, we roughly estimate the amplitude of electromagnetic noise in the Earths crust considering an average electrical conductivity of <σ>=10−3 S/m and a certain distance of the observatory to the earthquake epicenter.

  3. The LNG Industry - 2005

    International Nuclear Information System (INIS)

    2006-04-01

    First estimates for the marketed production of natural gas in 2005 show a rise of about 1.5 % over 2004. The share of LNG in the gas trade accounts for almost 21 % of the total. This annual report presents: 1 - LNG contracts and trade, 2 - Contracts concluded in 2005, 3 - LNG imports - Sources of imports - Quantities received in 2005 by the importing countries from the exporting countries, 4 - LNG tankers, 5 - 18 Ships delivered in 2005, 6 - Tanker distribution, 7 - Liquefaction plants, 8 - re-gasification plants, 9 - Long-term and medium-term contracts in force in 2005, 10 - Spot and short term quantities received in 2005 by the importing countries from the exporting countries, 11 - Sea transportation routes, 12 - Liquefaction plants (table), 13 - re-gasification plants (table), 14 - Delivery date of the LNG tankers

  4. Police chief : homicide down, crime rate constant in 2004 / Aleksei Gunter

    Index Scriptorium Estoniae

    Gunter, Aleksei, 1979-

    2005-01-01

    Politseiameti teatel avastati 2004. aastal rekordarv kuritegusid. Politseiameti peadirektor Robert Antropov politseitööst ja ümberkorraldustest politseis 2004. aastal. Lisa: Politsei prioriteedid 2004 ja 2005 aastal

  5. Total 2004 results

    International Nuclear Information System (INIS)

    2005-02-01

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  6. Diphtheria in the Dominican Republic: reduction of cases following a large outbreak.

    Science.gov (United States)

    Garib, Zacarías; Danovaro-Holliday, M Carolina; Tavarez, Yira; Leal, Irene; Pedreira, Cristina

    2015-10-01

    To describe the most recent outbreak of diphtheria in the Dominican Republic and the disease's occurrence and vaccination coverage in 2004-2013. Clinical data of diphtheria cases that occurred in 2004 and that met the study's case definition were reviewed along with socioeconomic and epidemiological information from the cases' families. Univariate and multivariate analyses were performed to assess risk factors for fatal diphtheria. Routine surveillance and vaccination coverage data are presented. From January 2004-April 2005, a total of 145 diphtheria cases were reported; 80 (66%) of the 122 cases reported in 2004 met the case definition; 26 were fatal (case-fatality rate: 32.5%). Incidence was highest in the group 1-4 years of age at 5.3 per 100 000; 62.5% were male. Of the 80 cases, 61 (76%) where hospitalized in Hospital A, 17 in Hospital B, and 2 in two other hospitals. Earlier onset (first half of 2004), birth order, and tracheotomy were associated with fatal diphtheria (P diphtheria incidence was 4.91 cases/1 million people in 2000-2003, climbed to 8.8 cases per million in 2004-2005, and dropped to 0.38 in 2006-2014; no diphtheria cases have been reported since 2011. DTP3 vaccination coverage ranged from 72%-81% in 2000-2004 and from 81%-89% in 2005-2013. The 2004-2005 diphtheria outbreak in the Dominican Republic resulted in important and avoidable morbidity and mortality. Annual cases declined and no cases have been reported in recent years. Maintaining high vaccination coverage and diligent surveillance are crucial to preventing diphtheria outbreaks and controlling the disease.

  7. Airborne thermal infrared imaging of the 2004-2005 eruption of Mount St. Helens

    Science.gov (United States)

    Schneider, D. J.; Vallance, J. W.; Logan, M.; Wessels, R.; Ramsey, M.

    2005-12-01

    A helicopter-mounted forward-looking infrared imaging radiometer (FLIR) documented the explosive and effusive activity at Mount St. Helens during the 2004-2005 eruption. A gyrostabilzed gimbal controlled by a crew member houses the FLIR radiometer and an optical video camera attached at the lower front of the helicopter. Since October 1, 2004 the system has provided an unprecedented data set of thermal and video dome-growth observations. Flights were conducted as frequently as twice daily during the initial month of the eruption (when changes in the crater and dome occurred rapidly), and have been continued on a tri-weekly basis during the period of sustained dome growth. As with any new technology, the routine use of FLIR images to aid in volcano monitoring has been a learning experience in terms of observation strategy and data interpretation. Some of the unique information that has been derived from these data to date include: 1) Rapid identification of the phreatic nature of the early explosive phase; 2) Observation of faulting and associated heat flow during times of large scale deformation; 3) Venting of hot gas through a short lived crater lake, indicative of a shallow magma source; 4) Increased heat flow of the crater floor prior to the initial dome extrusion; 5) Confirmation of new magma reaching the surface; 6) Identification of the source of active lava extrusion, dome collapse, and block and ash flows. Temperatures vary from ambient, in areas insulated by fault gouge and talus produced during extrusion, to as high as 500-740 degrees C in regions of active extrusion, collapse, and fracturing. This temperature variation needs to be accounted for in the retrieval of eruption parameters using satellite-based techniques as such features are sub-pixel size in satellite images.

  8. Burden of paediatric Rotavirus Gastroenteritis (RVGE and potential benefits of a universal Rotavirus vaccination programme with a pentavalent vaccine in Spain

    Directory of Open Access Journals (Sweden)

    Diez-Domingo Javier

    2010-08-01

    Full Text Available Abstract Background Rotavirus is the most common cause of gastroenteritis in young children worldwide. The aim of the study was to assess the health outcomes and the economic impact of a universal rotavirus vaccination programme with RotaTeq, the pentavalent rotavirus vaccine, versus no vaccination programme in Spain. Methods A birth cohort was followed up to the age of 5 using a cohort model. Epidemiological parameters were taken from the REVEAL study (a prospective epidemiological study conducted in Spain, 2004-2005 and from the literature. Direct and indirect costs were assessed from the national healthcare payer and societal perspectives by combining health care resource utilisation collected in REVEAL study and unit costs from official sources. RotaTeq per protocol efficacy data was taken from a large worldwide rotavirus clinical trial (70,000 children. Health outcomes included home care cases, General Practioner (GP/Paediatrician, emergency department visits, hospitalisations and nosocomial infections. Results The model estimates that the introduction of a universal rotavirus vaccination programme with RotaTeq (90% coverage rate would reduce the rotavirus gastroenteritis (RVGE burden by 75% in Spain; 53,692 home care cases, 35,187 GP/Paediatrician visits, 34,287 emergency department visits, 10,987 hospitalisations and 2,053 nosocomial infections would be avoided. The introduction of RotaTeq would avoid about 76% of RVGE-related costs from both perspectives: €22 million from the national health system perspective and €38 million from the societal perspective. Conclusions A rotavirus vaccination programme with RotaTeq would reduce significantly the important medical and economic burden of RVGE in Spain.

  9. Vedelgaasi kasutamine Eestis 2005. aastal / Sandor Tabo

    Index Scriptorium Estoniae

    Tabo, Sandor

    2006-01-01

    2005. a. kasvas Eestis vedelgaasi tarbimine võrreldes 2004. aastaga 11%. Diagramm: Vedelgaasi tarbimine Eestis 2005. a. tonnides. Graafik: Vedelgaasi propaan maailmaturu hind USD/tonn. Tabel Eesti vedelgaasiäriühingute terminalide võimsuse ja müügiviiside kohta

  10. Idosos vacinados e não vacinados contra a influenza: morbidade relatada e aspectos sociodemográficos, Porto Alegre (RS, Brasil, 2004 Influenza-vaccinated and non-vaccinated elderly: reported morbidity and sociodemographic aspects, Porto Alegre (RS, Brazil, 2004

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Müller Vilarino

    2010-09-01

    Full Text Available Aproveitando o evento da campanha nacional de vacinação de idosos contra o vírus influenza em 2004, realizou-se um estudo epidemiológico transversal descritivo com objetivo de comparar populações de idosos vacinadas e não vacinadas em relação à ocorrência de situações de doença ou internações hospitalares dentro do período de três meses após a vacinação. Não foi possível trabalhar com amostragem probabilística, e a tentativa de pareamento de idosos vacinados e não vacinados não teve sucesso devido à elevada cobertura vacinal observada (73% da população-alvo e ao curto espaço de tempo para obter as entrevistas. O resultado da análise descritiva dos 1.130 idosos entrevistados foi muito interessante, mesmo não sendo possível inferir para o universo de idosos de Porto Alegre. Encontrou-se maior proporção na população vacinada de pessoas na faixa etária de 70 a 79 anos (42% e na população não vacinada na faixa de 60 a 64 anos (40%. Os idosos vacinados são na maioria mais velhos; mulheres; têm plano de saúde; declaram renda mais elevada; realizam atividades físicas e não são fumantes. Os idosos não vacinados são na maioria homens; mais jovens; com menor renda; não realizam atividades físicas e são fumantes. Observou-se percentual menor de relato de pneumonias e internações hospitalares entre os vacinados em relação aos não vacinados.This descriptive transversal epidemiological study had the objective of comparing the elderly population who took the influenza vaccine and who did not regarding the occurrence of events of diseases or hospital admittances within three months after the vaccination. It was not possible to work with probable sampling and the attempt of pairing the vaccinated and non-vaccinated elderly was not successful due to the high vaccine coverage observed (73% of the target population and due to the short time available to make the interviews. The result of the descriptive

  11. Reduced All-Cause Child Mortality After General Measles Vaccination Campaign in Rural Guinea-Bissau

    DEFF Research Database (Denmark)

    Fisker, Ane Bærent; Rodrigues, Amabelia; Martins, Cesario

    2015-01-01

    BACKGROUND: Randomised trials have shown that measles vaccine (MV) prevents non-measles deaths. MV-campaigns are conducted to eliminate measles infection.The overall mortality effect of MV-campaigns has not been studied. METHODS: Bandim Health Project (BHP) surveys children aged 0-4 years in rural...... in the same age group during the two previous years. RESULTS: 8158 children aged 6-59 months were under BHP surveillance during the 2006-campaign and 7999 and 8108 during similar periods in 2004 and 2005. At least 90% of the eligible children received MV in the campaign. There were 161 non-accident deaths...

  12. Hepatitis A and B screening and vaccination rates among patients with chronic liver disease.

    Science.gov (United States)

    Ramirez, Jonathan C; Ackerman, Kimberly; Strain, Sasha C; Ahmed, Syed T; de Los Santos, Mario J; Sears, Dawn

    2016-01-01

    Vaccinations against hepatitis A virus (HAV) and hepatitis B virus (HBV) are recommended for patients with chronic liver disease (CLD), yet implementation of these recommendations is lacking. This study reviewed HAV and HBV antibody testing and vaccination status of patients with CLD. In 2008, we began using pre-printed liver order sets, which included vaccination options. We compared Scott & White liver clinic CLD patient records from 2005 (238) with patient records from 2008 (792). Screening rates for immunity and vaccination rates of those lacking immunity were calculated. In 2005, 66% of CLD patients were screened for HAV immunity. In 2008, 56% of CLD patients were screened. The HAV vaccination completion rate was 37% in 2005, while in 2008, the rate was 46%. In 2005, 66% of CLD patients were screened for HBV immunity; in 2008, 56 % CLD patients were screened. The HBV vaccination completion rate was 26% in 2005 compared with 36% in 2008. Although there was a lower percentage of screening in 2008, the overall number of patients tripled between 2005 and 2008. There was a significant increase in the total number of patients screened and vaccinated in 2008. Some physicians may have vaccinated their patients without checking for immunity. In January 2008, we implemented pre-printed order sets with checkboxes to help remind providers to order labs to screen for immunity against HAV and HBV and to order vaccinations for those who lacked immunity. The use of these sets may have aided in the increase of vaccination completion rates.

  13. Total 2004 results

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-01

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  14. Eesti maaelu arengukava 2004-2006 toetused / Ülle Puusta

    Index Scriptorium Estoniae

    Puusta, Ülle

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 71-72. Eesti maaelu arengukava meetmete rahastamisallikateks on EL-i eelarve (80%) ning Eesti riigieelarve (20%)

  15. Composition of gut microbiota and its influence on the immunogenicity of oral rotavirus vaccines.

    Science.gov (United States)

    Magwira, Cliff A; Taylor, Maureen B

    2018-05-08

    The introduction of oral rotavirus vaccines (ORVVs) has led to a reduction in number of hospitalisations and deaths due to rotavirus (RV) infection. However, the efficacy of the vaccines has been varied with low-income countries showing significantly lower efficacy as compared to high-income countries. The reasons for the disparity are not fully understood but are thought to be multi-factorial. In this review article, we discuss the concept that the disparity in the efficacy of oral rotavirus vaccines between the higher and lower socio-economical countries could be due the nature of the bacteria that colonises and establishes in the gut early in life. We further discuss recent studies that has demonstrated significant correlations between the composition of the gut bacteria and the immunogenicity of oral vaccines, and their implications in the development of novel oral RV vaccines or redesigning the current ones for maximum impact. Copyright © 2018. Published by Elsevier Ltd.

  16. Application of natural fibre composites in construction: a research case study

    CSIR Research Space (South Africa)

    Van Wyk, Llewellyn V

    2007-05-01

    Full Text Available properties. BACKGROUND In a report dated March 2005 (PDP TH/2004/20) the use of agricultural crops (animal and plant), recycled materials and industrial wastes as a material source for developing construction products was investigated (van Wyk 2005... materials (based on straw, hemp, cotton, flax, sisal and sugar cane fibres), paints, floor coverings, geotextiles, thatch, biopolymers and bio composites including board products, and starches for packaging. However, the report suggested...

  17. Does subsidy work? Price elasticity of demand for influenza vaccination among the elderly in Japan.

    Science.gov (United States)

    Kondo, Masahide; Hoshi, Shu-ling; Okubo, Ichiro

    2009-08-01

    Subsidy for influenza vaccination is often provided to the elderly in order to encourage them to receive a flu shot in developed countries. However, its effect on uptake rate, i.e., price elasticity of demand, has not been well studied. Japan's decentralised vaccination programme allows observation of various pairs in price and uptake rate of flu shots among the elderly by the municipality from 2001/2002 to 2004/2005 season. We combine our sample survey data (n=281), which monitor price, subsidy and uptake rate, with published data on local characteristics in order to estimate price elasticity of demand with panel model. We find price elasticity of demand for influenza vaccine: nearly zero in nationwide, nearly zero in urban area, and -1.07 in rural area. The results question the rationale for subsidy, especially in urban area. There are cases where maintaining or increasing the level of subsidy is not an efficient allocation of finite health care resources. When organising a vaccination programme, health manager should be careful about the balance between subsidy and other efforts in order to encourage the elderly to receive shots with price elasticity in mind.

  18. Epidemiological and molecular surveillance of influenza and respiratory syncytial viruses in children with acute respiratory infections (2004/2005 season

    Directory of Open Access Journals (Sweden)

    Alessandra Zappa

    2008-03-01

    Full Text Available Objective. During the 2004/2005 influenza season an active virological surveillance of influenza viruses and respiratory syncytial virus (RSV was carried out to monitor the epidemiologic trend of acute respiratory infections (ARI in the paediatric community. Materials and methods. 100 patients (51 males, 49 females; mean age: 19 months, either treated at the Emergency Unit or hospitalized in the Pediatric Unit of “San Carlo Borromeo Hospital” (Milan, reporting symptoms related to ARI were enrolled. Pharyngeal swabs were collected for virological investigation by: 1 multiplexnested- PCR for the simultaneous identification of both influenza A and B viruses and RSV; 2 multiplex-nested- PCR for the subtyping of influenza A viruses (H1 and H3. Results. 12% (12/100 subjects were infected with influenza A virus, 4% (4/100 with influenza B virus and 14 (14% with RSV. Of all the 12 influenza A positive samples 4 (33.3% belonged to subtype H1 and 8 (66.7% to subtype H3. Bronchiolitis and bronchitis episodes were significantly higher among RSV-infected subjects than among influenza- infected subjects (42.8% vs 6.2%; p<0.05 and 35.7% vs 6.2%; p<0.05, respectively. Pneumonia episodes occurred similarly both in influenza-infected children and in RSV-infected ones. Conclusions. During the 2004/2005 influenza season, influenza viruses and RSV were liable for high morbidity among paediatric subjects.The present study underlies the importance of planning an active surveillance of respiratory viral infections among paediatric cases requiring hospitalization due to ARI.A thorough analysis of target population features, of viruses antigenic properties and seasonality will be decisive in the evaluation of each clinical event.

  19. Diphtheria in the Dominican Republic: reduction of cases following a large outbreak

    Directory of Open Access Journals (Sweden)

    Zacarías Garib

    Full Text Available OBJECTIVE: To describe the most recent outbreak of diphtheria in the Dominican Republic and the disease's occurrence and vaccination coverage in 2004-2013. METHODS: Clinical data of diphtheria cases that occurred in 2004 and that met the study's case definition were reviewed along with socioeconomic and epidemiological information from the cases' families. Univariate and multivariate analyses were performed to assess risk factors for fatal diphtheria. Routine surveillance and vaccination coverage data are presented. RESULTS: From January 2004-April 2005, a total of 145 diphtheria cases were reported; 80 (66% of the 122 cases reported in 2004 met the case definition; 26 were fatal (case-fatality rate: 32.5%. Incidence was highest in the group 1-4 years of age at 5.3 per 100 000; 62.5% were male. Of the 80 cases, 61 (76% where hospitalized in Hospital A, 17 in Hospital B, and 2 in two other hospitals. Earlier onset (first half of 2004, birth order, and tracheotomy were associated with fatal diphtheria (P < 0.05; cases in Hospital A were also more likely to be fatal (P = 0.066. The average annual diphtheria incidence was 4.91 cases/1 million people in 2000-2003, climbed to 8.8 cases per million in 2004-2005, and dropped to 0.38 in 2006-2014; no diphtheria cases have been reported since 2011. DTP3 vaccination coverage ranged from 72%-81% in 2000-2004 and from 81%-89% in 2005-2013. CONCLUSIONS: The 2004-2005 diphtheria outbreak in the Dominican Republic resulted in important and avoidable morbidity and mortality. Annual cases declined and no cases have been reported in recent years. Maintaining high vaccination coverage and diligent surveillance are crucial to preventing diphtheria outbreaks and controlling the disease.

  20. AFSC/ABL: Lynn Canal Overwinter Acoustic Survey, 2004-2005

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The acoustic trawl database for Lynn Canals echo-trawl survey was conducted from 2001 to 2004 throughout southern Lynn Canal in southeast Alaska. Acoustic surveys...

  1. Annual report of R and D activities in center for promotion of computational science and engineering from April 1, 2004 to March 31, 2005

    International Nuclear Information System (INIS)

    2005-09-01

    This report provides an overview of research and development activities in Center for Promotion of Computational Science and Engineering (CCSE), JAERI, in the fiscal year 2004 (April 1, 2004 - March 31, 2005). The activities have been performed by Research Group for Computational Science in Atomic Energy, Research Group for Computational Material Science in Atomic Energy, R and D Group for Computer Science, R and D Group for Numerical Experiments, and Quantum Bioinformatics Group in CCSE. The ITBL (Information Technology Based Laboratory) project is performed mainly by the R and D Group for Computer Science and the Research Group for Computational Science in Atomic Energy. According to the mid-term evaluation for the ITBL project conducted by the MEXT, the achievement of the ITBL infrastructure software developed by JAERI has been remarked as outstanding at the 13th Information Science and Technology Committee in the Subdivision on R and D Planning and Evaluation of the Council for Science and Technology on April 26th, 2004. (author)

  2. The composition of demand for newly launched vaccines: results from the pneumococcal and rotavirus vaccine introductions in Ethiopia and Malawi.

    Science.gov (United States)

    Williams, B Adam; Kidane, Teklay; Chirwa, Geoffrey; Tesfaye, Neghist; Prescott, Marta R; Scotney, Soleine T; Valle, Moussa; Abebe, Sintayehu; Tambuli, Adija; Malewezi, Bridget; Mohammed, Tahir; Kobayashi, Emily; Wootton, Emily; Wong, Renee; Dosani, Rahima; Subramaniam, Hamsa; Joseph, Jessica; Yavuz, Elif; Apple, Aliza; Le Tallec, Yann; Kang'ethe, Alice

    2016-06-01

    Understanding post-launch demand for new vaccines can help countries maximize the benefits of immunization programmes. In particular, low- and middle-income countries (LMICs) should ensure adequate resource planning with regards to stock consumption and service delivery for new vaccines, whereas global suppliers must produce enough vaccines to meet demand. If a country underestimates the number of children seeking vaccination, a stock-out of commodities will create missed opportunities for saving lives. We describe the post-launch demand for the first dose of pneumococcal conjugate vaccine (PCV1) in Ethiopia and Malawi and the first dose of rotavirus vaccine (Rota1) in Malawi, with focus on the new birth cohort and the 'backlog cohort', comprised of older children who are still eligible for vaccination at the time of launch. PCV1 and Rota1 uptake were compared with the demand for the first dose of pentavalent vaccine (Penta1), a routine immunization that targets the same age group and immunization schedule. In the first year, the total demand for PCV1 was 37% greater than that of Penta1 in Ethiopia and 59% greater in Malawi. In the first 6 months, the demand of Rota1 was only 5.9% greater than Penta1 demand in Malawi. Over the first three post-introduction months, 70.7% of PCV1 demand in Ethiopia and 71.5% of demand in Malawi came from children in the backlog cohort, whereas only 28.0% of Rota1 demand in Malawi was from the backlog cohort. The composition of demand was impacted by time elapsed since vaccine introduction and age restrictions. Evidence suggests that countries' plans should account for the impact of backlog demand, especially in the first 3 months post-introduction. LMICs should request for higher stock volumes when compared with routine needs, plan social mobilization activities to reach the backlog cohort and allocate human resources and cold chain capacity to accommodate high demand following vaccine introduction. © The Author 2016. Published by

  3. Alberta's reserves 2004 and supply/demand outlook 2005-2014

    International Nuclear Information System (INIS)

    Burrowes, A.; Marsh, R.; Ramdin, N.; Evans, C.; Kirsch, M.A.; Philp, L.; Fujda, M.; Stenson, J.; Sadler, K.; Sankey, G.; Hill, C.; Rahnama, F.; Habib, G.; MacGillivray, J.

    2005-01-01

    This document presents information on the state of reserves, supply, and demand for Alberta's energy resources including bitumen, crude oil, coalbed methane (CBM), conventional natural gas, natural gas liquids, sulphur, and coal. Estimates of initial reserves, remaining established reserves, and ultimate potential were also included, along with a 10-year supply and demand forecast for Alberta's energy resources. The document presents major forecast assumptions that influence Alberta's energy supply and demand. Some of the main variables affecting energy supply and demand include the global oil market, energy prices, Canadian economic performance and the economic outlook for Alberta. The development of Alberta's energy resources depends on reserve supply, costs of development, energy demands, conservation, and social, economic and environmental considerations. In 2004, raw bitumen production continued to grow and accounted for 69 per cent of Alberta's total crude oil and bitumen production. The value-added process of upgrading raw bitumen to synthetic crude oil was also expanded in 2004. Natural gas production from all sources in Alberta increased by 1 per cent compared with 2003. CBM development also increased greatly in 2004. Although it accounted for 80 per cent of the cumulative CBM production to date, it only contributed 0.5 per cent of the provincial total natural gas production. It is expected that CBM development will continue to increase in the coming years. For that reason, a separate estimate of CBM reserves was included. tabs., figs

  4. Vaccinatietoestand Nederland per 1 januari 2004

    NARCIS (Netherlands)

    Abbink F; Oomen PJ; Zwakhals SLN; Melker HE de; Ambler-Huiskes A; Landelijke Vereniging van; IGZ; CIE

    2005-01-01

    This report describes the progress of the National Immunization Programme (NIP) in the Netherlands. Immunization coverage figures as at 1 january 2004 are presented for all vaccines used in the NIP for agecohorts born in 1993, 1998 and 2001.For years national immunization coverage in the Netherlands

  5. Genetic characterization and molecular epidemiology of foot-and-mouth disease viruses isolated from Afghanistan in 2003-2005.

    Science.gov (United States)

    Schumann, Kate R; Knowles, Nick J; Davies, Paul R; Midgley, Rebecca J; Valarcher, Jean-Francois; Raoufi, Abdul Quader; McKenna, Thomas S; Hurtle, William; Burans, James P; Martin, Barbara M; Rodriguez, Luis L; Beckham, Tammy R

    2008-04-01

    Foot-and-mouth disease virus (FMDV) isolates collected from various geographic locations in Afghanistan between 2003 and 2005 were genetically characterized, and their phylogeny was reconstructed utilizing nucleotide sequences of the complete VP1 coding region. Three serotypes of FMDV (types A, O, and Asia 1) were identified as causing clinical disease in Afghanistan during this period. Phylogenetic analysis revealed that the type A viruses were most closely related to isolates collected in Iran during 2002-2004. This is the first published report of serotype A in Afghanistan since 1975, therefore indicating the need for inclusion of serotype A in vaccine formulations that will be used to control disease outbreaks in this country. Serotype O virus isolates were closely related to PanAsia strains, including those that originated from Bhutan and Nepal during 2003-2004. The Asia 1 viruses, collected along the northern and eastern borders of Afghanistan, were most closely related to FMDV isolates collected in Pakistan during 2003 and 2004. Data obtained from this study provide valuable information on the FMDV serotypes circulating in Afghanistan and their genetic relationship with strains causing FMD in neighboring countries.

  6. FY 2005 Supplement to the President`s Budget

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — The Supplement to the President`s FY 2005 Budget reports on the FY 2004 research and development R and D activities and FY 2005 plans of the multiagency Networking...

  7. Gaps in vaccine financing for underinsured children in the United States.

    Science.gov (United States)

    Lee, Grace M; Santoli, Jeanne M; Hannan, Claire; Messonnier, Mark L; Sabin, James E; Rusinak, Donna; Gay, Charlene; Lett, Susan M; Lieu, Tracy A

    2007-08-08

    The number of new vaccines recommended for children and adolescents has nearly doubled during the past 5 years, and the cost of fully vaccinating a child has increased dramatically in the past decade. Anecdotal reports from state policy makers and clinicians suggest that new gaps have arisen in financial coverage of vaccines for children who are underinsured (ie, have private insurance that does not cover all recommended vaccines). In 2000, approximately 14% of children were underinsured for vaccines in the United States. To describe variation among states in the provision of new vaccines to underinsured children and to identify barriers to state purchase and distribution of new vaccines. A 2-phase mixed-methods study of state immunization program managers in the United States. The first phase included 1-hour qualitative telephone interviews conducted from November to December 2005 with 9 program managers chosen to represent different state vaccine financing policies. The second phase incorporated findings from phase 1 to develop a national telephone and paper-based survey of state immunization program managers that was conducted from January to June 2006. Percentage of states in which underinsured children are unable to receive publicly purchased vaccines in the private or public sectors. Immunization program managers from 48 states (96%) participated in the study. Underinsured children were not eligible to receive publicly purchased meningococcal conjugate or pneumococcal conjugate vaccines in the private sector in 70% and 50% of states, respectively, or in the public sector in 40% and 17% of states, respectively. Due to limited financing for new vaccines, 10 states changed their policies for provision of publicly purchased vaccines between 2004 and early 2006 to restrict access to selected new vaccines for underinsured children. The most commonly cited barriers to implementation in underinsured children were lack of sufficient federal and state funding to

  8. Fuel use and emissions from non-road machinery in Denmark from 1985-2004 - and projections from 2005-2030

    International Nuclear Information System (INIS)

    Winther, M.; Nielsen, Ole-Kenneth

    2006-01-01

    This report documents the updated 1985-2004 fuel use and emission inventory for non road machinery and recreational craft in Denmark. The inventory comprises the emission components of SO 2 , NO x , NMVOC, CH 4 , CO, CO 2 , N 2 O, NH 3 and TSP, and in addition a fuel use and emission forecast is presented from 2005-2030. The calculated results are grouped into the sub-sectors agriculture, forestry, industry, household/gardening and inland waterways, according to the structure of the CollectER database used for all Danish sources. The report explains the existing EU emission directives for non road machinery, the actual fuel use and emission factors used, sources of background and operational data, calculation methods and the calculated fuel use and emission results. (au)

  9. Births: preliminary data for 2005.

    Science.gov (United States)

    Hamilton, Brady E; Martin, Joyce A; Ventura, Stephanie J

    2006-12-28

    This report presents preliminary data for 2005 on births in the United States. U.S. data on births are shown by age, live-birth order, race, and Hispanic origin of mother. Data on marital status, cesarean delivery, preterm births, and low birthweight (LBW) are also presented. Data in this report are based on 99.2 percent of births for 2005. The records are weighted to independent control counts of all births received in state vital statistics offices in 2005. Comparisons are made with 2004 data. The crude birth rate in 2005 was 14.0 births per 1,000 total population, unchanged from 2004. The general fertility rate, however, rose to 66.7 births per 1,000 women aged 15-44 years in 2005, the highest level since 1993. The birth rate for teenagers declined by 2 percent in 2005, falling to 40.4 births per 1,000 women aged 15-19 years, the lowest ever recorded in the 65 years for which a consistent series of rates are available. The rate declined for teenagers 15-17 years to 21.4 births per 1,000, but was essentially stable for older teenagers 18-19 years. The birth rate for women aged 20-24 years rose in 2005, whereas the rate for women aged 25-29 years was essentially unchanged. The birth rates for women aged 30 years and over rose to levels not seen in almost 40 years. Childbearing by unmarried women increased to record levels for the Nation in 2005. The birth rate rose 3 percent to 47.6 births per 1,000 unmarried women aged 15-44 years; the proportion of all births to unmarried women increased to 36.8 percent. The cesarean delivery rate rose by 4 percent in 2005 to 30.2 percent of all births, another record high for the Nation. The preterm birth rate continued to rise (to 12.7 percent in 2005) as did the rate for LBW births (8.2 percent).

  10. Very Low Prevalence of Vaccine Human Papillomavirus Types Among 18- to 35-Year Old Australian Women 9 Years Following Implementation of Vaccination.

    Science.gov (United States)

    Machalek, Dorothy A; Garland, Suzanne M; Brotherton, Julia M L; Bateson, Deborah; McNamee, Kathleen; Stewart, Mary; Rachel Skinner, S; Liu, Bette; Cornall, Alyssa M; Kaldor, John M; Tabrizi, Sepehr N

    2018-04-23

    A quadrivalent human papillomavirus vaccination program targeting females aged 12-13 years commenced in Australia in 2007, with catch-up vaccination of 14-26 year olds through 2009. We evaluated the program's impact on HPV prevalence among women aged 18-35 in 2015. HPV prevalence among women aged 18-24 and 25-35 was compared with prevalence in these age groups in 2005-2007. For women aged 18-24, we also compared prevalence with that in a postvaccine study conducted in 2010-2012. For the 2015 sample, Vaccination Register-confirmed 3-dose coverage was 53.3% (65.0% and 40.3% aged 18-24 and 25-35, respectively). Prevalence of vaccine HPV types decreased from 22.7% (2005-2007) and 7.3% (2010-2012), to 1.5% (2015) (P trend women aged 18-24, and from 11.8% (2005-2007) to 1.1% (2015) (P = .001) among those aged 25-35. This study, reporting the longest surveillance follow-up to date, shows prevalence of vaccine-targeted HPV types has continued to decline among young women. A substantial fall also occurred in women aged 25-35, despite lower coverage. Strong herd protection and effectiveness of less than 3 vaccine doses likely contributed to these reductions.

  11. k0-INAA for APM samples collected in period of June 2004 - March 2005 and some marine certified reference materials

    International Nuclear Information System (INIS)

    Dung, Ho Manh; Vu, Cao Dong; Y, Truong; Sy, Nguyen Thi

    2006-01-01

    The airborne particulate matter (APM) samples have been collected in 2004 using two types of polycarbonate membrane filter PM 2.5 and PM 2.5-10 at two sites of industrial (Ho Chi Mihn City) and rural (Dateh) regions in south of Vietnam. Three marine certified reference materials have been selected to establish a k0-NAA procedure for marine samples. The concentration of trace multi-element in the samples has been determined by the k 0 -INAA procedure using K o -DALAT software developed in Dalat NRI. About 28 elements in 224 APM samples collected at two areas of Dateh and HCMC of Vietnam in period from June, 2004 to March, 2005 were presented in report. The statistical analysis was applied to the data set to investigate the pollution source at sampling sites. The results proved that the k 0 -NAA on the Dalat research reactor is a reliable and effective analytical technique for characterization of trace multi-element in APM and marine samples for air and marine environmental pollution study in Vietnam. (author)

  12. Oceanographic water temperature and salinity profiles from CTD casts collected aboard the Navigation Response Team 6 in the Pacific Ocean from 2004-10-07 to 2005-07-19 (NODC Accession 0002666)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using CTD casts in the Northeast Pacific Ocean from the NAVIGATION RESPONSE TEAM 6 from 07 October 2004 to 19 July 2005. Data...

  13. Critical Analysis of Compositions and Protective Efficacies of Oral Killed Cholera Vaccines

    Science.gov (United States)

    2014-01-01

    Two cholera vaccines, sold as Shanchol and Dukoral, are currently available. This review presents a critical analysis of the protective efficacies of these vaccines. Children under 5 years of age are very vulnerable to cholera and account for the highest incidence of cholera cases and more than half of the resulting deaths. Both Shanchol and Dukoral are two-spaced-dose oral vaccines comprising large numbers of killed cholera bacteria. The former contains Vibrio cholerae O1 and O139 cells, and the latter contains V. cholerae O1 cells with the recombinant B subunit of cholera toxin. In a field trial in Kolkata (India), Shanchol, the preferred vaccine, protected 45% of the test subjects in all of the age groups and only 17% of the children under 5 years of age during the first year of surveillance. In a field trial in Peru, two spaced doses of Dukoral offered negative protection in children under 5 years of age and little protection (15%) in vaccinees over 6 years of age during the first year of surveillance. Little is known about Dukoral's long-term protective efficacy. Both of these vaccines have questionable compositions, using V. cholerae O1 strains isolated in 1947 that have been inactivated by heat and formalin treatments that may denature protein. Immunological studies revealed Dukoral's reduced and short-lived efficacy, as measured by several immunological endpoints. Various factors, such as the necessity for multiple doses, poor protection of children under 5 years of age, the requirement of a cold supply chain, production costs, and complex logistics of vaccine delivery, greatly reduce the suitability of either of these vaccines for endemic or epidemic cholera control in resource-poor settings. PMID:25056361

  14. Report of the IAEA Nuclear Data Section to the International Nuclear Data Committee for the period January 2004 - December 2005

    Energy Technology Data Exchange (ETDEWEB)

    Nichols, A L [International Atomic Energy Agency, Nuclear Data Section, Vienna (Austria)

    2006-05-15

    This report contains details of the main activities of the IAEA Nuclear Data Section (NDS) in 2004 and 2005, as information to the International Nuclear Data Committee (INDC). Work of NDS staff and their consultants has focused on the continued data development and ensuring adequate, trouble-free services to all users in Member States. This information is complemented with descriptions of other related activities in the reporting period, including meetings and publications. The atomic and molecular data programmes are presented to the INDC for their information only, since these specific activities are reviewed in depth by the A+M Subcommittee of the International Fusion Research Council. (author)

  15. Report of the IAEA Nuclear Data Section to the International Nuclear Data Committee for the period January 2004 - December 2005

    International Nuclear Information System (INIS)

    Nichols, A.L.

    2006-05-01

    This report contains details of the main activities of the IAEA Nuclear Data Section (NDS) in 2004 and 2005, as information to the International Nuclear Data Committee (INDC). Work of NDS staff and their consultants has focused on the continued data development and ensuring adequate, trouble-free services to all users in Member States. This information is complemented with descriptions of other related activities in the reporting period, including meetings and publications. The atomic and molecular data programmes are presented to the INDC for their information only, since these specific activities are reviewed in depth by the A+M Subcommittee of the International Fusion Research Council. (author)

  16. Status of air quality in arenas in the Abitibi-Temiscamingue 2004-2005

    International Nuclear Information System (INIS)

    Gagne, D.

    2005-01-01

    The air quality was checked in 24 of 26 arenas in Quebec's Abitibi-Temiscamingue region during the intensive tournament season from November 2004 to March 2005. Carbon monoxide (CO) levels were measured in 24 arenas, while nitrogen dioxide (NO 2 ) levels were measured in 22 arenas during and after intensive use of the ice surfacing machine. The air quality respected the public health criteria for CO and NO 2 in 87 and 95 per cent of the arenas, respectively. The main factors that influence the ambient air quality in the arenas included the maintenance of the ice surfacing machine, the system of radiant heating and ventilation of combustion gases. In more than half of the arenas, the ice surfacing machine had been tuned prior to the active season. In 28 per cent of the arenas, maintenance inspections were carried out only twice during the season. Two arenas were equipped with an electric ice surfacing machine. All arenas had a mechanical ventilation system. It was concluded that the proportion of arenas that do not respect public health criteria at the time of monitoring varied between 4 and 23 per cent. While the negligence of operators is often in question, the failures of ventilation systems or a contamination by external sources of CO are often unforeseeable. For these reasons, it was recommended that annual monitoring should be conducted by an external organization. 9 refs., 7 figs.

  17. Academic Training: 2004 - 2005 ACADEMIC TRAINING PROGRAMME

    CERN Multimedia

    Françoise Benz

    2004-01-01

    1st Term - 01 October to 17 December 2004 REGULAR LECTURE PROGRAMME New Trends in Fusion Research by A. Fasoli, EPFL, Lausanne, CH 11, 12, 13 October Physics at e+e- linear collider by K. Desch, DESY, Hamburg, D 15, 16, 17, 18, 19 November LECTURE SERIES FOR POSTGRADUATE STUDENTS Standard Model by R. Barbieri, CERN-PH-TH 6, 7, 8, 9 10 December The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc) will be published in the CERN Bulletin, the WWW, and by notices before each term and for each series of lectures.

  18. La fiscalización sin dientes en el gobierno del estado de Sonora 2004 y 2005

    Directory of Open Access Journals (Sweden)

    Nicolás Pineda Pablos

    2011-01-01

    Full Text Available Este trabajo aborda dos temas relacionados con la revisión de las cuentas públicas de la administración directa dependiente del ejecutivo del estado de Sonora. Uno es indagar qué tantas faltas o deficiencias se encuentran en la revisión de las cuentas públicas y cómo se hacen las observaciones y señalamientos. El segundo es ver si, en los casos de las observaciones, se aplican sanciones y si se busca reparar el daño. Para ello, se analizaron las observaciones de los informes de resultados de los años 2004 y 2005 y se indagó sobre los procedimientos de solventación y sanciones aplicadas. El estudio arroja que hay deficiencias serias en la de rendición de cuentas y que es vaga y difusa a la hora de resolver las deficiencias y de la aplicación de sanciones.

  19. INJURY PROFILE IN WOMEN SHOTOKAN KARATE CHAMPIONSHIPS IN IRAN(2004-2005

    Directory of Open Access Journals (Sweden)

    Farzin Halabchi

    2007-10-01

    Full Text Available The aims of this paper were to record injury rates among Iranian women competitive Shotokan karate athletes and propose possible predisposing factors. A prospective recording of the injuries resulting from all matches in 6 consecutive women national Shotokan Karate Championships in all age groups in Iran (season 2004-2005 was performed. Data recorded included demographic characteristics (Age and Weight, athletic background (rank, years of experience, time spent training and previous injuries, type, location and reason for the injury, and the result of the match. Results indicate 186 recorded injuries from a total of 1139 bouts involving 1019 athletes, therefore there were 0.163 injury per bout [C.I. 95%: 0.142-0.184] and 183 injuries per 1000 athletes [C.I. 95%: 159-205]. Injuries were most commonly located in the head and neck (55.4% followed by the lower limb (21%, upper limb (12.9% and trunk (10.8%. Punches (48. 4% were associated with more injuries than kicks (33.3%. The injuries consisted of muscle strain and contusion (81, 43.6%, hematoma and epistaxis (49, 26.3%, lacerations and abrasions (28, 15. 1%, concussion (13, 7%, tooth avulsion or subluxation (3, 1.6%, joint dislocation (3, 1.6% and fractures (3, 1.6%. In conclusion, as the majority of injuries are minor, and severe or longstanding injuries are uncommon, it can be argued that shotokan karate is a relatively safe for females, despite its image as a combat sport, where ostensibly the aim appears to injure your opponent. Further research is needed to evaluate the effective strategies to minimize the risk of injuries

  20. Fuel use and emissions from non-road machinery in Denmark from 1985-2004 - and projections from 2005-2030

    Energy Technology Data Exchange (ETDEWEB)

    Winther, M.; Nielsen, Ole-Kenneth [National Environmental Research Inst. (Denmark)

    2006-08-31

    This report documents the updated 1985-2004 fuel use and emission inventory for non road machinery and recreational craft in Denmark. The inventory comprises the emission components of SO{sub 2}, NO{sub x}, NMVOC, CH{sub 4}, CO, CO{sub 2}, N{sub 2}O, NH{sub 3} and TSP, and in addition a fuel use and emission forecast is presented from 2005-2030. The calculated results are grouped into the sub-sectors agriculture, forestry, industry, household/gardening and inland waterways, according to the structure of the CollectER database used for all Danish sources. The report explains the existing EU emission directives for non road machinery, the actual fuel use and emission factors used, sources of background and operational data, calculation methods and the calculated fuel use and emission results. (au)

  1. Report: Audit of EPA’s Fiscal 2005 and 2004 Consolidated Financial Statements

    Science.gov (United States)

    Report #2006-1-00015, November 14, 2005. EPA converted to a new payroll system in fiscal 2005. While EPA was able to resolve many issues arising from the conversion, we noted several reportable conditions.

  2. Bacteriological cure rate and changes in milk composition in mastitis vaccinated ewes affected with subclinical mastitis.

    Science.gov (United States)

    Alekish, Myassar O; Ismail, Z Bani; Hammouri, H M; Daradka, M H; Taha, S Al; Olymat, I

    2018-02-01

    The aim of this study was to investigate the effects of using a commercially-available polyvalent mastitis vaccine on the bacteriological cure rate of existing subclinical mastitis in Awassi sheep. A total of 164 lactating ewes were divided into two main groups according to udder health and milk somatic cell count (SCC): Group 1=normal (N; n=80) and Group 2=subclinical mastitis (SC; n=84). Each group was then subdivided randomly into two treatment groups: N vaccinated (N vax ; n=38), N non-vaccinated (N nvax ; n=42), SC vaccinated (SC vax ; n=42), and SC non-vaccinated (SC nvax ; n=42). The vaccine was administered as per manufacturer's recommendations. Milk samples were collected aseptically from all ewes before vaccine administration (T0) and again on days 28 (T2) and 42 (T3) of the experiment. In the SC group, the bacteriological cure rates in vaccinated and non-vaccinated ewes were 76% and 69%, respectively. In N group, the new intramammary infection rates in vaccinated and non-vaccinated ewes were 48% and 50%, respectively. Vaccination of normal ewes resulted in a significant (pewes on days 28 and 42 was 19% and 20%, respectively. The prevalence of new intramammary infection rate in N nvax group on days 28 and 42 was 33% and 30%, respectively. In SC vax group, the bacterial growth rate on days 28 and 42 was 44% and 35%, respectively. In SC nvax group, the bacterial growth rate on days 28 and 42 was 27% and 32%, respectively. There was no statistically significant effect of vaccination on any of the studied milk composition parameters. This is a preliminary study that indicated a possible protective effect of vaccination against mastitis in sheep. Further, case-controlled studies are indicated to estimate the level of immunity this vaccine provides to vaccinated sheep.

  3. Academic Training: 2004 - 2005 ACADEMIC TRAINING PROGRAMME

    CERN Multimedia

    Françoise Benz

    2004-01-01

    1st Term - 01 October to 17 December 2004 REGULAR LECTURE PROGRAMME New Trends in Fusion Research by A. Fasoli, EPFL, Lausanne, CH 11, 12, 13 October Physics at e+e- linear collider by K. Desch, DESY, Hamburg, D 15, 16, 17, 18, 19 November LECTURE SERIES FOR POSTGRADUATE STUDENTS Standard Model by R. Barbieri, CERN-PH-TH 6, 7, 8, 9 10 December The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc) will be published in the CERN Bulletin, the WWW, and by notices before each term and for each series of lectures. ENSEIGNEMENT ACADEMIQUE ACADEMIC TRAINING Françoise Benz 73127 academic.training@cern.ch

  4. Black lives matter: Differential mortality and the racial composition of the U.S. electorate, 1970-2004.

    Science.gov (United States)

    Rodriguez, Javier M; Geronimus, Arline T; Bound, John; Dorling, Danny

    2015-07-01

    Excess mortality in marginalized populations could be both a cause and an effect of political processes. We estimate the impact of mortality differentials between blacks and whites from 1970 to 2004 on the racial composition of the electorate in the US general election of 2004 and in close statewide elections during the study period. We analyze 73 million US deaths from the Multiple Cause of Death files to calculate: (1) Total excess deaths among blacks between 1970 and 2004, (2) total hypothetical survivors to 2004, (3) the probability that survivors would have turned out to vote in 2004, (4) total black votes lost in 2004, and (5) total black votes lost by each presidential candidate. We estimate 2.7 million excess black deaths between 1970 and 2004. Of those, 1.9 million would have survived until 2004, of which over 1.7 million would have been of voting-age. We estimate that 1 million black votes were lost in 2004; of these, 900,000 votes were lost by the defeated Democratic presidential nominee. We find that many close state-level elections over the study period would likely have had different outcomes if voting age blacks had the mortality profiles of whites. US black voting rights are also eroded through felony disenfranchisement laws and other measures that dampen the voice of the US black electorate. Systematic disenfranchisement by population group yields an electorate that is unrepresentative of the full interests of the citizenry and affects the chance that elected officials have mandates to eliminate health inequality. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. John Maynard Smith (1920-2004)

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 11. John Maynard Smith (1920-2004) - “One of the last Grand Evolutionary Theorists of the 20th Century”. Vidyanand Nanjundiah. General Article Volume 10 Issue 11 November 2005 pp 70-78 ...

  6. The future of HIV vaccine research and the role of the Global HIV Vaccine Enterprise.

    Science.gov (United States)

    Voronin, Yegor; Manrique, Amapola; Bernstein, Alan

    2010-09-01

    This review covers the role of the Global HIV Vaccine Enterprise (the Enterprise), an alliance of independent organizations committed to development of a safe and effective HIV vaccine. It discusses the history, impact on the field, and future directions and initiatives of the alliance in the context of recent progress in HIV vaccine research and development. Significant progress has been made in the field since the release of the 2005 Scientific Strategic Plan (the Plan) of the Enterprise. Over the last year, the Enterprise embarked on an impact assessment of the 2005 Plan and the development of the 2010 Plan. Enterprise Working Groups identified key priorities in the field, several of which are discussed in this review, including changing the nature, purpose and process of clinical trials, increasing and facilitating data sharing, and optimizing existing and mobilizing new resources. This time is an important moment in HIV vaccine research. New clinical trial and laboratory results have created new opportunities to advance the search for an HIV vaccine and reinvigorated the field. The Enterprise will publish its 2010 Plan this year, providing a framework for setting new priorities and directions and encouraging new and existing partners to embark on a shared scientific agenda.

  7. Microbial compositional changes in broiler chicken cecal contents from birds challenged with different Salmonella vaccine candidate strains.

    Science.gov (United States)

    Park, Si Hong; Kim, Sun Ae; Rubinelli, Peter M; Roto, Stephanie M; Ricke, Steven C

    2017-05-31

    Previously, we constructed and characterized the vaccine efficacy of Salmonella Typhimurium mutant strains in poultry with either inducible mviN expression (P BAD -mviN) or methionine auxotrophy (ΔΔmetRmetD). The aim of the present study was to assess potential impact of these Salmonella vaccine strains on the cecal microbiota using a next generation sequencing (NGS). The cecal microbial community obtained from unvaccinated (group 1) and vaccinated chickens (group 2, vaccinated with P BAD -mviN; group 3, vaccinated with wild type; group 4, vaccinated with ΔΔmetRmetD) were subjected to microbiome sequencing analysis with an Illumina MiSeq platform. The NGS microbiome analysis of chicken ceca revealed considerable changes in microbial composition in the presence of the different vaccine strains and exhibited detectable patterns of distinctive clustering among the respective groups (the R value of unweighted PCoA plot was 0.68). The present study indicates that different S. Typhimurium vaccine strains can differentially influence the microbiota of the ceca in terms of presence but not in the relative abundance of microbiota. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Heterologous Prime-Boost Vaccination Using an AS03B-Adjuvanted Influenza A(H5N1) Vaccine in Infants and Children <3 Years of Age

    Science.gov (United States)

    Nolan, Terry; Izurieta, Patricia; Lee, Bee-Wah; Chan, Poh Chong; Marshall, Helen; Booy, Robert; Drame, Mamadou; Vaughn, David W.

    2014-01-01

    Background. Protecting young children from pandemic influenza should also reduce transmission to susceptible adults, including pregnant women. Methods. An open study assessed immunogenicity and reactogenicity of a heterologous booster dose of A/turkey/Turkey/1/2005(H5N1)-AS03B (AS03B is an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion [5.93 mg tocopherol]) in infants and children aged 6 to < 36 months that was given 6 months following 2-dose primary vaccination with A/Indonesia/05/2005(H5N1)-AS03B. Vaccines contained 1.9 µg of hemagglutinin antigen and AS03B. Hemagglutinin inhibition (HI) responses, microneutralization titers, and antineuraminidase antibody levels were assessed for 6 months following the booster vaccination. Results. For each age stratum (defined on the basis of the subject's age at first vaccination as 6 to < 12 months, 12 to < 24 months, and 24 to < 36 months) and overall (n = 113), European influenza vaccine licensure criteria were fulfilled for responses to A/turkey/Turkey/1/2005(H5N1) 10 days following the booster vaccination. Local pain and fever increased with consecutive doses. Anamnestic immune responses were demonstrated for HI, neutralizing, and antineuraminidase antibodies against vaccine-homologous/heterologous strains. Antibody responses to vaccine-homologous/heterologous strains persisted in all children 6 months following the booster vaccination. Conclusions. Prevaccination of young children with a clade 2 strain influenza A(H5N1) AS03-adjuvanted vaccine followed by heterologous booster vaccination boosted immune responses to the homologous strain and a related clade, with persistence for at least 6 months. The results support a prime-boost vaccination approach in young children for pandemic influenza preparedness. Clinical Trials Registration. NCT01323946. PMID:24973461

  9. Effect of human papillomavirus (HPV) vaccination on clinical indicators of sexual behaviour among adolescent girls: the Ontario Grade 8 HPV Vaccine Cohort Study.

    Science.gov (United States)

    Smith, Leah M; Kaufman, Jay S; Strumpf, Erin C; Lévesque, Linda E

    2015-02-03

    Suboptimal human papillomavirus (HPV) vaccine coverage in some jurisdictions is partly attributed to fears that vaccination may increase risky sexual behaviour. We assessed the effect of HPV vaccination on clinical indicators of sexual behaviour among adolescent girls in Ontario. Using Ontario's administrative health databases, we identified a population-based cohort of girls in grade 8 in the 2 years before (2005/06 and 2006/07) and after (2007/08 and 2008/09) implementation of Ontario's grade 8 HPV vaccination program. For each girl, we then obtained data on vaccine receipt in grades 8 and 9 and data on indicators of sexual behaviour (pregnancy and non-HPV-related sexually transmitted infections) in grades 10-12. Using a quasi-experimental method known as regression discontinuity, we estimated, for each outcome, the risk difference (RD) and relative risk (RR) attributable to vaccination and to program eligibility. The cohort comprised 260 493 girls, of whom 131 781 were ineligible for the program and 128 712 were eligible. We identified 15 441 (5.9%) cases of pregnancy and sexually transmitted infection and found no evidence that vaccination increased the risk of this composite outcome: RD per 1000 girls -0.61 (95% confidence interval [CI] -10.71 to 9.49) and RR 0.96 (95% CI 0.81 to 1.14). Similarly, we found no discernible effect of program eligibility: RD per 1000 girls -0.25 (95% CI -4.35 to 3.85) and RR 0.99 (95% CI 0.93 to 1.06). The findings were similar when outcomes were assessed separately. We present strong evidence that HPV vaccination does not have any significant effect on clinical indicators of sexual behaviour among adolescent girls. These results suggest that concerns over increased promiscuity following HPV vaccination are unwarranted and should not deter from vaccinating at a young age. © 2015 Canadian Medical Association or its licensors.

  10. Proceedings of the Topical Sessions on Media Relations held in June 2004 and 2005

    International Nuclear Information System (INIS)

    2006-01-01

    An effective media strategy, including timely interaction with them is an indispensable tool for organisations or institutions involved in radioactive waste management. With this in mind, the Forum on Stakeholder Confidence (FSC) set up a Group on Communication and Outreach with a twofold objective: to assist FSC members in communicating with the radioactive waste management community, to assist FSC members in reaching a broader public. As part of this assignment, the Group organised two Topical Sessions on media strategy, in conjunction with the 2004 and 2005 FSC meetings. The main objective was to learn about the functioning of the media organisations, their structures and needs, with speakers chosen to represent the range of such media, as well as different countries and varying radioactive waste situations that may serve as illustrative examples, given the vast differences that may prevail between local, national, and international radioactive waste management situations and their treatment by the media. The sessions were attended by representatives of policy makers, regulators and implementers from the FSC organisations. The presentations and discussions illustrated current media strategies, best practices, successes and failures and lessons learn. These proceedings consist of a summary of the main points made by each speaker as well a collation of their papers

  11. G8 global partnership. 2004-2005-2006 activity report; Partenariat mondial du G8. Rapport d'activite 2004-2005-2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The Global Partnership Against the Spread of Weapons and Materials of Mass Destruction was launched by the heads of state and government of the G8 at the G8 summit in Kananaskis in June 2002. Fourteen other countries have since joined this G8 initiative. The aim of this partnership is to 'prevent terrorists, or those who harbor them, from acquiring or developing nuclear, chemical radiological and biological weapons, missiles, and related materials, equipment and technology'. Within the framework of the Partnership, the participants have agreed to support cooperation projects, starting with Russia, to promote non-proliferation, disarmament, the fight against terrorism and nuclear safety. The destruction of chemical weapons, the dismantling of decommissioned nuclear submarines, the disposal of fissile materials and the employment of former weapons scientists are among the priority concerns expressed. Ukraine has also been a beneficiary of this partnership since 2004. The participants in this initiative have agreed to contribute up to 20 billion dollars (up to 750 million euros from France) to support these projects over a period of ten years from 2002. A group of experts from the G8 on the Global Partnership (the GPWG = Global Partnership Working Group) meets regularly and gives an account of the progress made with this initiative in its annual report to the G8. These annual reports are published at the G8 summits. This document is the 2004 to 2006 activity report of the G8 global partnership.

  12. Status of air quality in arenas in the Abitibi-Temiscamingue 2004-2005; Portrait de la qualite de l'air dans les arenas de l'Abitibi-Temiscamingue 2004-2005

    Energy Technology Data Exchange (ETDEWEB)

    Gagne, D. (ed.)

    2005-09-13

    The air quality was checked in 24 of 26 arenas in Quebec's Abitibi-Temiscamingue region during the intensive tournament season from November 2004 to March 2005. Carbon monoxide (CO) levels were measured in 24 arenas, while nitrogen dioxide (NO{sub 2}) levels were measured in 22 arenas during and after intensive use of the ice surfacing machine. The air quality respected the public health criteria for CO and NO{sub 2} in 87 and 95 per cent of the arenas, respectively. The main factors that influence the ambient air quality in the arenas included the maintenance of the ice surfacing machine, the system of radiant heating and ventilation of combustion gases. In more than half of the arenas, the ice surfacing machine had been tuned prior to the active season. In 28 per cent of the arenas, maintenance inspections were carried out only twice during the season. Two arenas were equipped with an electric ice surfacing machine. All arenas had a mechanical ventilation system. It was concluded that the proportion of arenas that do not respect public health criteria at the time of monitoring varied between 4 and 23 per cent. While the negligence of operators is often in question, the failures of ventilation systems or a contamination by external sources of CO are often unforeseeable. For these reasons, it was recommended that annual monitoring should be conducted by an external organization. 9 refs., 7 figs.

  13. Teraviljatoodete tootmine, tarbimine ja kaubandus : [1994-2004 Eestis] / Taavi Kuntu

    Index Scriptorium Estoniae

    Kuntu, Taavi

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 34-41. Teravilja, teraviljasaadusi ja muid toiduaineid töötlev tööstus annab väärtuseliselt ligikaudu 18% Eesti toiduainetööstuse kogutoodangust. Diagrammid. Tabel

  14. Resultados econômicos da atividade leiteira na região de Lavras (MG nos anos 2004 e 2005: um estudo multicasos Economical results of milk production systems in Lavras region (MG throughout the years 2004 and 2005: a multicase study

    Directory of Open Access Journals (Sweden)

    M.A. Lopes

    2008-04-01

    Full Text Available Estudou-se a rentabilidade da atividade leiteira de 17 propriedades da região de Lavras/MG e identificaram-se os componentes que exerceram maior influência sobre os custos finais da atividade. Os dados foram coletados mensalmente durante o período de janeiro de 2004 a dezembro de 2005. Considerou-se a margem bruta, a margem líquida e o resultado (lucro ou prejuízo como indicadores de eficiência econômica. Os itens componentes do custo operacional efetivo que exerceram maior influência sobre os custos da atividade leiteira foram, em ordem decrescente, alimentação (55,9%, mão-de-obra (19,1%, despesas diversas (11,3%, energia (7,1%, sanidade (4,9%, ordenha (0,74%, impostos (0,74% e inseminação artificial (0,23%. A margem líquida e o resultado positivo indicam que os pecuaristas têm condições de produzir a médio e a longo prazo, com conseqüente capitalização. Os resultados do estudo não podem ser extrapolados por não se tratar de uma amostra probabilística.It was studied the profitability of the milk production in 17 properties in the region of Lavras (MG, and the components that had the greatest influence on the final costs of the business were identified. The data were monthly collected from January 2004 to December 2005. The gross margin, net margin, and the result (profit or loss were taken into consideration as indicators of economic efficiency. The component items of the effective operational cost that had the greatest influence upon the costs of dairy business were, in decreasing order, feeding (55.9%, labor (19.1%, different expenses (11.3%, energy (7.1%, health (4.9%, milking (0.74%, taxes (0.74%, and artificial insemination (0,23%. The net margin and the positive result show the farmers have conditions to produce in middle and long terms, with consequent capitalization. Although, the results of the study can not be extrapolated, since they do not represent a random sampling.

  15. Modeling lost production from destroyed platforms in the 2004-2005 Gulf of Mexico hurricane seasons

    International Nuclear Information System (INIS)

    Kaiser, Mark J.; Yu, Yunke; Jablonowski, Christopher J.

    2009-01-01

    Hurricanes Ivan, Katrina, and Rita passed through the Gulf of Mexico during 2004 and 2005 and resulted in the largest number of destroyed and damaged offshore oil and gas structures in the history of Gulf operations. In the final official government assessment, a total of 126 platforms were destroyed and over 183 structures were identified as having extensive damage. Production associated with wells and structures that are not redeveloped are classified as lost. The purpose of this paper is to derive functional relations that describe the likely contribution the collection of destroyed assets would have made to future production in the Gulf of Mexico. We estimate that the total remaining reserves from the set of destroyed structures range in value between 1.3 and 4.5 billion depending on the assumptions employed. We summarize the impact of the storms on the Gulf of Mexico oil and gas infrastructure and discuss the main issues involved in redevelopment decision making. A meta-model analytic framework is applied to perform sensitivity analysis and to explore the interactions of assumptions on model output. A discussion of the limitations of the analysis is presented. (author)

  16. CFBP and LPG market in 2004

    International Nuclear Information System (INIS)

    Anon.

    2005-01-01

    The French butane and propane committee (CFBP) has presented its activities in liquefied petroleum gases in its 2004 annual report. The success of its initiatives of promotion during the year 2004 has led the CFBP to launch a new campaign of advertisement since January 31, 2005. In its report, the CFBP stresses on the re-start up of the LPG fuel market. The sales of propane gas in tanks have raised by 5.2% between 2003 and 2004. The decay of the traditional market of gas cylinders has been practically stopped thanks to the sales dynamism of small (5-6 kg) cylinders and to the innovations added by some retailers on the 13 kg cylinders (level indicator). The sales of automotive LPG fuels have shown a slower decay during 2004. (J.S.)

  17. Technical Cooperation Report for 2004. Report by the Director General; Informe de Cooperacion Tecnica para 2004. Informe del Director General

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-08-15

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  18. Spatial and temporal variability in nutrients and carbon uptake during 2004 and 2005 in the eastern equatorial Pacific Ocean

    DEFF Research Database (Denmark)

    Palacz, A. P.; Chai, F.

    2012-01-01

    The eastern equatorial Pacific plays a great role in the global carbon budget due to its enhanced biological productivity linked to the equatorial upwelling. However, as confirmed by the Equatorial Biocomplexity cruises in 2004 and 2005, nutrient upwelling supply varies strongly, partly due...... and intraseasonal time scales. Here, high resolution Pacific ROMS-CoSiNE (Regional Ocean Modeling System-Carbon, Silicon, Nitrogen Ecosystem) model results were evaluated with in situ and remote sensing data. The results of model-data comparison revealed a good agreement in domain-average hydrographic....... In order to fully resolve the complexity of biological and physical interactions in the eastern equatorial Pacific, we recommended improving CoSiNE and other models by introducing more phytoplankton groups, variable Redfield and carbon to chlorophyll ratios, as well as resolving the Fe-Si co...

  19. TIARA annual report 2004

    International Nuclear Information System (INIS)

    Ohara, Yoshihiro; Arakawa, Kazuo; Tanaka, Shigeru; Narumi, Kazumasa; Yoshida, Masaru; Itoh, Hisayoshi; Yoshikawa, Masato; Tanaka, Atsushi; Kobayashi, Yasuhiko; Fukuda, Mitsuhiro; Otsubo, Michiro; Yokota, Watalu; Nakamura, Yoshiteru

    2006-01-01

    This annual report describes research and development activities which have been performed with the TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 2004 to March 31, 2005. The 126 of the presented papers are indexed individually. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (J.P.N.)

  20. Restoring Anadromous Fish Habitat in Big Canyon Creek Watershed, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen, Lynn (Nez Perce Soil and Conservation District, Lewiston, ID)

    2006-07-01

    The ''Restoring Anadromous Fish Habitat in the Big Canyon Creek Watershed'' is a multi-phase project to enhance steelhead trout in the Big Canyon Creek watershed by improving salmonid spawning and rearing habitat. Habitat is limited by extreme high runoff events, low summer flows, high water temperatures, poor instream cover, spawning gravel siltation, and sediment, nutrient and bacteria loading. Funded by the Bonneville Power Administration (BPA) as part of the Northwest Power Planning Council's Fish and Wildlife Program, the project assists in mitigating damage to steelhead runs caused by the Columbia River hydroelectric dams. The project is sponsored by the Nez Perce Soil and Water Conservation District. Target fish species include steelhead trout (Oncorhynchus mykiss). Steelhead trout within the Snake River Basin were listed in 1997 as threatened under the Endangered Species Act. Accomplishments for the contract period September 1, 2004 through October 31, 2005 include; 2.7 riparian miles treated, 3.0 wetland acres treated, 5,263.3 upland acres treated, 106.5 riparian acres treated, 76,285 general public reached, 3,000 students reached, 40 teachers reached, 18 maintenance plans completed, temperature data collected at 6 sites, 8 landowner applications received and processed, 14 land inventories completed, 58 habitat improvement project designs completed, 5 newsletters published, 6 habitat plans completed, 34 projects installed, 2 educational workshops, 6 displays, 1 television segment, 2 public service announcements, a noxious weed GIS coverage, and completion of NEPA, ESA, and cultural resources requirements.

  1. Local resistance to the global eradication of polio: newspaper coverage of the 2003-2004 vaccination stoppage in northern Nigeria.

    Science.gov (United States)

    Olufowote, James Olumide

    2011-12-01

    Successful global health initiatives are executed on the recognition that globalization involves simultaneous pulls between global unification and fragmentation. This article responds to the need for more understanding of the role of fragmentation in global health initiatives through analyses of 52 northern Nigerian newspaper reports of the 2003-2004 northern Nigerian stoppage of the Global Polio Eradication Initiative. By 2009 the stoppage had resulted in an epidemic in Nigeria and polio importations in 20 previously polio-free countries. Findings pointed to beliefs in contemporary forms of Western control and abuse through global organizations (nongovernmental organizations and for-profits), understandings of the "philanthropy" of the West and global organizations as self-serving and malevolent, and doubts about the polio vaccine product.

  2. Cost analysis of bluetongue virus serotype 8 surveillance and vaccination programmes in Austria from 2005 to 2013.

    Science.gov (United States)

    Pinior, Beate; Lebl, Karin; Firth, Clair; Rubel, Franz; Fuchs, Reinhard; Stockreiter, Simon; Loitsch, Angelika; Köfer, Josef

    2015-11-01

    This study was designed to evaluate the costs between 2005 and 2013 of the national bluetongue virus (BTV) surveillance and vaccination programmes before, during and after the BTV serotype 8 (BTV-8) outbreak in Austria commencing in 2008. In addition to an assessment of the temporal development of costs, a spatial cost analysis was performed. Within the context of this study, the term 'costs' refers to actual financial expenditure and imputed monetary costs for contributions in-kind. Costs were financed directly by the private-public sectors, by the European Commission (EC), and (in-kind) by responsible national institutions and individuals (e.g. blood sampling by veterinarians). The total net cost of the BTV-8 surveillance and vaccination programmes arising from the outbreak amounted to €22.8 million (0.86% of the national agricultural Gross Value Added), of which 32% was allocated to surveillance and 68% to the vaccination programme. Of the total programme costs, the EC supplied €4.9 million, while the remaining costs (€18 million) were directly financed from national resources. Of the latter, €14.5 million was classed as public costs, including €2 million contributions in-kind, and €3.4 million as private costs. The assessment of the costs revealed heterogeneous temporal and spatial distributions. The methodology of this analysis might assist decision makers in calculating costs for other surveillance and intervention programmes. The assessment of contributions in-kind is of importance to public authorities as it increases visibility of the available resources and shows how they have been employed. This study also demonstrates the importance of tracking changing costs per payer over time. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  3. Pelagic Project Mauritania 2005-2006

    NARCIS (Netherlands)

    Heessen, H.J.L.; Tjoe-Awie, P.J.; Haan, de D.; Ybema, M.S.

    2007-01-01

    The Pelagic Project Mauritania 2005-2006 was the continuation of two earlier, but similar, projects for the years 1998-2001 and 2002-2004. The project was carried out in cooperation between IMARES and IMROP and had as most important objectives to further the assessment of small pelagic species,

  4. The National Football League Combine: performance differences between drafted and nondrafted players entering the 2004 and 2005 drafts.

    Science.gov (United States)

    Sierer, S Patrick; Battaglini, Claudio L; Mihalik, Jason P; Shields, Edgar W; Tomasini, Nathan T

    2008-01-01

    The purpose of this study was to examine performance differences between drafted and nondrafted athletes (N = 321) during the 2004 and 2005 National Football League (NFL) Combines. We categorized players into one of 3 groups: Skill, Big skill, and Linemen. Skill players (SP) consisted of wide receivers, cornerbacks, free safeties, strong safeties, and running backs. Big skill players (BSP) included fullbacks, linebackers, tight ends, and defensive ends. Linemen (LM) consisted of centers, offensive guards, offensive tackles, and defensive tackles. We analyzed player height and mass, as well as performance on the following combine drills: 40-yard dash, 225-lb bench press test, vertical jump, broad jump, pro-agility shuttle, and the 3-cone drill. Student t-tests compared performance on each of these measures between drafted and nondrafted players. Statistical significance was found between drafted and nondrafted SP for the 40-yard dash (P ready themselves for the NFL Combine.

  5. Konjunktuuribaromeetrid : juuni 2005 / K. Martens, A. Vanamölder, E. Ahermaa...[jt.

    Index Scriptorium Estoniae

    2005-01-01

    Ilmunud ka: Konjunktuur : Quarterly Review of the Estonian Economy, 2005/Aug, nr. 2, lk. 13-42. Tööstus-, ehitus-, kaubandus-, teenindus- ja tarbijabaromeetri näitajad juunis 2005. Prognoosid lähikuudeks. Töötleva tööstuse investeeringud 2004. aastal, prognoos 2005. aastaks. Graafikud, diagrammid, tabelid

  6. Brotes de rabia humana transmitida por vampiros en los municipios de Bajo y Alto Baudó, departamento del Chocó, Colombia 2004-2005

    OpenAIRE

    Jessika Valderrama; Ingrid García; Germán Figueroa; Edilberto Rico; Juliana Sanabria; Nicolás Rocha; Edgar Parra; Cecilia Saad; Andrés Páez

    2006-01-01

    Introducción. Entre mayo y julio de 2004 ocurrió en la comunidad Embera de Birrinchao de cuenca del río Purricha, Bajo Baudó, Chocó un brote de rabia humana con 14 víctimas. En enero de 2005 otro brote similar ocurrió en las comunidades negras de Pató y Nauca, Alto Baudó, Chocó, con tres nuevas víctimas. Objetivos. Describir los brotes de rabia humana transmitida por vampiros de mayor magnitud hasta ahora reportados en Colombia. Describir las técnicas diagnósticas utilizadas y las acciones...

  7. Development of chitosan-pullulan composite nanoparticles for nasal delivery of vaccines: in vivo studies.

    Science.gov (United States)

    Cevher, Erdal; Salomon, Stefan K; Somavarapu, Satyanarayana; Brocchini, Steve; Alpar, H Oya

    2015-01-01

    Here, we aimed at developing chitosan/pullulan composite nanoparticles and testing their potential as novel systems for the nasal delivery of diphtheria toxoid (DT). All the chitosan derivatives [N-trimethyl (TMC), chloride and glutamate] and carboxymethyl pullulan (CMP) were synthesised and antigen-loaded composites were prepared by polyion complexation of chitosan and pullulan derivatives (particle size: 239-405 nm; surface charge: +18 and +27 mV). Their immunological effects after intranasal administration to mice were compared to intramuscular route. Composite nanoparticles induced higher levels of IgG responses than particles formed with chitosan derivative and antigen. Nasally administered TMC-pullulan composites showed higher DT serum IgG titre when compared with the other composites. Co-encapsulation of CpG ODN within TMC-CMP-DT nanoparticles resulted in a balanced Th1/Th2 response. TMC/pullulan composite nanoparticles also induced highest cytokine levels compared to those of chitosan salts. These findings demonstrated that TMC-CMP-DT composite nanoparticles are promising delivery system for nasal vaccination.

  8. Vaccination coverage and reasons for non-vaccination in a district of Istanbul

    Directory of Open Access Journals (Sweden)

    Bakırcı Nadi

    2006-05-01

    Full Text Available Abstract Background In order to control and eliminate the vaccine preventable diseases it is important to know the vaccination coverage and reasons for non-vaccination. The primary objective of this study was to determine the complete vaccination rate; the reasons for non-vaccination and the predictors that influence vaccination of children. The other objective was to determine coverage of measles vaccination of the Measles Immunization Days (MID 2005 for children aged 9 month to 6 years in a region of Umraniye, Istanbul, Turkey. Methods A '30 × 7' cluster sampling design was used as the sampling method. Thirty streets were selected at random from study area. Survey data were collected by a questionnaire which was applied face to face to parents of 221 children. A Chi-square test and logistic regression was used for the statistical analyses. Content analysis method was used to evaluate the open-ended questions. Results The complete vaccination rate for study population was 84.5% and 3.2% of all children were totally non-vaccinated. The siblings of non-vaccinated children were also non-vaccinated. Reasons for non-vaccination were as follows: being in the village and couldn't reach to health care services; having no knowledge about vaccination; the father of child didn't allow vaccination; intercurrent illness of child during vaccination time; missed opportunities like not to shave off a vial for only one child. In logistic regression analysis, paternal and maternal levels of education and immigration time of both parents to Istanbul were found to influence whether children were completely vaccinated or non-vaccinated. Measles vaccination coverage during MID was 79.3%. Conclusion Efforts to increase vaccination coverage should take reasons for non-vaccination into account.

  9. SOLID WASTE INTEGRATED FORECAST TECHNICAL (SWIFT) REPORT FY2005 THRU FY2035 2005.0 VOLUME 2

    Energy Technology Data Exchange (ETDEWEB)

    BARCOT, R.A.

    2005-08-17

    This report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. It includes: (1) an overview of Hanford-wide solid waste to be managed by the WM Project; (2) multi-level and waste class-specific estimates; (3) background information on waste sources; and (4) comparisons to previous forecasts and other national data sources. The focus of this report is low-level waste (LLW), mixed low-level waste (MLLW), and transuranic waste, both non-mixed and mixed (TRU(M)). Some details on hazardous waste are also provided, however, this information is not considered comprehensive. This report includes data requested in December, 2004 with updates through March 31,2005. The data represent a life cycle forecast covering all reported activities from FY2005 through the end of each program's life cycle and are an update of the previous FY2004.1 data version.

  10. Evidence of increased toxic Alexandrium tamarense dinoflagellate blooms in the eastern Bering Sea in the summers of 2004 and 2005.

    Directory of Open Access Journals (Sweden)

    Masafumi Natsuike

    Full Text Available The eastern Bering Sea has a vast continental shelf, which contains various endangered marine mammals and large fishery resources. Recently, high numbers of toxic A. tamarense resting cysts were found in the bottom sediment surface of the eastern Bering Sea shelf, suggesting that the blooms have recently occurred. However, little is known about the presence of A. tamarense vegetative cells in the eastern Bering Sea. This study's goals were to detect the occurrence of A. tamarense vegetative cells on the eastern Bering Sea shelf and to find a relationship between environmental factors and their presence. Inter-annual field surveys were conducted to detect A. tamarense cells and environmental factors, such as nutrients, salinity, chlorophyll a, and water temperature, along a transect line on the eastern Bering Sea shelf during the summers of 2004, 2005, 2006, 2009, 2012, and 2013. A. tamarense vegetative cells were detected during every sampling year, and their quantities varied greatly from year to year. The maximum cell densities of A. tamarense observed during the summers of 2004 and 2005 were much higher than the Paralytic shellfish poisoning warning levels, which are greater than 100-1,000 cells L-1, in other subarctic areas. Lower quantities of the species occurred during the summers of 2009, 2012, and 2013. A significant positive correlation between A. tamarense quantity and water temperature and significant negative correlations between A. tamarense quantity and nutrient concentrations (of phosphate, silicate, and nitrite and nitrate were detected in every sampling period. The surface- and bottom-water temperatures varied significantly from year to year, suggesting that water temperatures, which have been known to affect the cell growth and cyst germination of A. tamarense, might have affected the cells' quantities in the eastern Bering Sea each summer. Thus, an increase in the Bering Sea shelf's water temperature during the summer will

  11. Evidence of increased toxic Alexandrium tamarense dinoflagellate blooms in the eastern Bering Sea in the summers of 2004 and 2005.

    Science.gov (United States)

    Natsuike, Masafumi; Saito, Rui; Fujiwara, Amane; Matsuno, Kohei; Yamaguchi, Atsushi; Shiga, Naonobu; Hirawake, Toru; Kikuchi, Takashi; Nishino, Shigeto; Imai, Ichiro

    2017-01-01

    The eastern Bering Sea has a vast continental shelf, which contains various endangered marine mammals and large fishery resources. Recently, high numbers of toxic A. tamarense resting cysts were found in the bottom sediment surface of the eastern Bering Sea shelf, suggesting that the blooms have recently occurred. However, little is known about the presence of A. tamarense vegetative cells in the eastern Bering Sea. This study's goals were to detect the occurrence of A. tamarense vegetative cells on the eastern Bering Sea shelf and to find a relationship between environmental factors and their presence. Inter-annual field surveys were conducted to detect A. tamarense cells and environmental factors, such as nutrients, salinity, chlorophyll a, and water temperature, along a transect line on the eastern Bering Sea shelf during the summers of 2004, 2005, 2006, 2009, 2012, and 2013. A. tamarense vegetative cells were detected during every sampling year, and their quantities varied greatly from year to year. The maximum cell densities of A. tamarense observed during the summers of 2004 and 2005 were much higher than the Paralytic shellfish poisoning warning levels, which are greater than 100-1,000 cells L-1, in other subarctic areas. Lower quantities of the species occurred during the summers of 2009, 2012, and 2013. A significant positive correlation between A. tamarense quantity and water temperature and significant negative correlations between A. tamarense quantity and nutrient concentrations (of phosphate, silicate, and nitrite and nitrate) were detected in every sampling period. The surface- and bottom-water temperatures varied significantly from year to year, suggesting that water temperatures, which have been known to affect the cell growth and cyst germination of A. tamarense, might have affected the cells' quantities in the eastern Bering Sea each summer. Thus, an increase in the Bering Sea shelf's water temperature during the summer will increase the

  12. Cost-effectiveness of Rotavirus vaccination in Vietnam

    Directory of Open Access Journals (Sweden)

    Goldie Sue J

    2009-01-01

    Full Text Available Abstract Background Rotavirus is the most common cause of severe diarrhea leading to hospitalization or disease-specific death among young children. New rotavirus vaccines have recently been approved. Some previous studies have provided broad qualitative insights into the health and economic consequences of introducing the vaccines into low-income countries, representing several features of rotavirus infection, such as varying degrees of severity and age-dependency of clinical manifestation, in their model-based analyses. We extend this work to reflect additional features of rotavirus (e.g., the possibility of reinfection and varying degrees of partial immunity conferred by natural infection, and assess the influence of the features on the cost-effectiveness of rotavirus vaccination. Methods We developed a Markov model that reflects key features of rotavirus infection, using the most recent data available. We applied the model to the 2004 Vietnamese birth cohort and re-evaluated the cost-effectiveness (2004 US dollars per disability-adjusted life year [DALY] of rotavirus vaccination (Rotarix® compared to no vaccination, from both societal and health care system perspectives. We conducted univariate sensitivity analyses and also performed a probabilistic sensitivity analysis, based on Monte Carlo simulations drawing parameter values from the distributions assigned to key uncertain parameters. Results Rotavirus vaccination would not completely protect young children against rotavirus infection due to the partial nature of vaccine immunity, but would effectively reduce severe cases of rotavirus gastroenteritis (outpatient visits, hospitalizations, or deaths by about 67% over the first 5 years of life. Under base-case assumptions (94% coverage and $5 per dose, the incremental cost per DALY averted from vaccination compared to no vaccination would be $540 from the societal perspective and $550 from the health care system perspective. Conclusion

  13. Brancherapport: Z-org benchmarkonderzoek thuiszorg 2004.

    NARCIS (Netherlands)

    2005-01-01

    In 2004-2005 werd voor de derde keer binnen de thuiszorg een benchmarkonderzoek gehouden. Dit qua opzet en scope unieke onderzoek is gehouden onder de leden van Z-org. Het is een vergelijkend onderzoek onder klanten, medewerkers en binnen de zorgorganisaties zelf waarbij het de bedoeling is te leren

  14. Societal threat, authoritarianism, conservatism, and U.S. state death penalty sentencing (1977-2004).

    Science.gov (United States)

    McCann, Stewart J H

    2008-05-01

    On the basis of K. Stenner's (2005) authoritarian dynamic theory, it was hypothesized that the number of death sentences and executions would be higher in more threatened conservative states than in less threatened conservative states, and would be lower in more threatened liberal states than in less threatened liberal states. Threat was based on state homicide rate, violent crime rate, and non-White percentage of population. Conservatism was based on state voter ideological identification, Democratic and Republican Party elite liberalism-conservatism, policy liberalism-conservatism, religious fundamentalism, degree of economic freedom, and 2004 presidential election results. For 1977-2004, with controls for state population and years with a death penalty provision, the interactive hypothesis received consistent support using the state conservatism composite and voter ideological identification alone. As well, state conservatism was related to death penalties and executions, but state threat was not. The temporal stability of the findings was demonstrated with a split-half internal replication using the periods 1977-1990 and 1991-2004. The interactive hypothesis and the results also are discussed in the context of other threat-authoritarianism theories and terror management theory. (c) 2008 APA, all rights reserved

  15. PERILAKU RISIKO TINGGI PENULARAN HIV PADA REMAJA DI INDONESIA, 2004-2005

    Directory of Open Access Journals (Sweden)

    Dina Bisara Lolong

    2012-11-01

    Full Text Available The major routes for HIV transmission in Indonesia are injecting drug use and heterosexual activity. More than halve of the proportion of estimation 2006 of people living with HIV/AIDS were IDUs. Around 70 percent of all reported AIDS cases of IDUs in Indonesia occur among those in the age group of15-29 years. It indicates that young people are not only at high risk of contracting HIV infection but already constitute a significant percentage of people living with HIV/AIDS. This article is examines adolescent risk behavior on HIV transmission in Indonesia. The data were obtained from Behavioral Surveillance Survey 2004-2005 of 6352 female sex workers and 2969 their clients in 14 provinces, 1052 transsexual in four provinces, and 1795 IDUs in five cities as well as 1001 male student and 1159 female student in two cities. This survey reveals that adolescent's high risk behavior on HIV transmission is not only through injecting drug use but also through heterosexual. Of great concern is that 40 percent of the female sex workers and more than halve of IDUs aged 15-24 years. Findings also show that risk behavior is associated with age of respondent. Younger ages of IDUs were more like to have more than one sex partners and sharing needle; and again 27 percent of younger ages 15-19 year have started to be involved in high risk behavior as IDUs age below 15 compared to age 20-24 and 25+ nine and one percent respectively. Furthermore, the younger ages of sex workers and their clients were less likely to use condoms; and around 25-60 percent of them have begun to work as commercial sex workers age below 20.The findings of this survey raise concern about risk behavior of HIV transmission among adolescent. The need to focus more policy and program attention on adolescent sexuality and drug use behavior is compelling. Keywords : adolescence, risk behavior, HIV transmission

  16. Injury Profile in Women Shotokan Karate Championships in Iran (2004-2005)

    Science.gov (United States)

    Halabchi, Farzin; Ziaee, Vahid; Lotfian, Sarah

    2007-01-01

    The aims of this paper were to record injury rates among Iranian women competitive Shotokan karate athletes and propose possible predisposing factors. A prospective recording of the injuries resulting from all matches in 6 consecutive women national Shotokan Karate Championships in all age groups in Iran (season 2004-2005) was performed. Data recorded included demographic characteristics (Age and Weight), athletic background (rank, years of experience, time spent training and previous injuries), type, location and reason for the injury, and the result of the match. Results indicate 186 recorded injuries from a total of 1139 bouts involving 1019 athletes, therefore there were 0.163 injury per bout [C.I. 95%: 0.142-0.184] and 183 injuries per 1000 athletes [C.I. 95%: 159-205]. Injuries were most commonly located in the head and neck (55.4%) followed by the lower limb (21%), upper limb (12.9%) and trunk (10.8%). Punches (48. 4%) were associated with more injuries than kicks (33.3%). The injuries consisted of muscle strain and contusion (81, 43.6%), hematoma and epistaxis (49, 26.3%), lacerations and abrasions (28, 15. 1%), concussion (13, 7%), tooth avulsion or subluxation (3, 1.6%), joint dislocation (3, 1.6%) and fractures (3, 1.6%). In conclusion, as the majority of injuries are minor, and severe or longstanding injuries are uncommon, it can be argued that shotokan karate is a relatively safe for females, despite its image as a combat sport, where ostensibly the aim appears to injure your opponent. Further research is needed to evaluate the effective strategies to minimize the risk of injuries. Key points 186 injuries were recorded during women competitions. Incidence rates of 0.163 injury per bout and 183 injuries per 1000 athletes were calculated. The injuries were most commonly located in the head and neck. Muscle strain and contusion, hematoma and epistaxis constitute the majority of injuries. PMID:24198704

  17. Emerging pneumococcal carriage serotypes in a high-risk population receiving universal 7-valent pneumococcal conjugate vaccine and 23-valent polysaccharide vaccine since 2001

    Directory of Open Access Journals (Sweden)

    Stubbs Liz

    2009-08-01

    Full Text Available Abstract Background In Australia in June 2001, a unique pneumococcal vaccine schedule commenced for Indigenous infants; seven-valent pneumococcal conjugate vaccine (7PCV given at 2, 4, and 6 months of age and 23-valent pneumococcal polysaccharide vaccine (23PPV at 18 months of age. This study presents carriage serotypes following this schedule. Methods We conducted cross sectional surveys of pneumococcal carriage in Aboriginal children 0 to 6 years of age living in remote Aboriginal communities (RACs in 2003 and 2005. Nasal secretions were collected and processed according to published methods. Results 902 children (mean age 25 months living in 29 communities in 2003 and 818 children (mean age 35 months in 17 communities in 2005 were enrolled. 87% children in 2003 and 96% in 2005 had received two or more doses of 7PCV. From 2003 to 2005, pneumococcal carriage was reduced from 82% to 76% and reductions were apparent in all age groups; 7PCV-type carriage was reduced from 11% to 8%, and 23PPV-non-7PCV-type carriage from 31% to 25% respectively. Thus non-23PPV-type carriage increased from 57% to 67%. All these changes were statistically significant, as were changes for some specific serotypes. Shifts could not be attributed to vaccination alone. The top 10 of 40 serotypes identified were (in descending order 16F, 19A, 11A, 6C, 23B, 19F, 6A, 35B, 6B, 10A and 35B. Carriage of penicillin non-susceptible (MIC > = 0.12 μg/mL strains (15% overall was detected in serotypes (descending order 19A, 19F, 6B, 16F, 11A, 9V, 23B, and in 4 additional serotypes. Carriage of azithromycin resistant (MIC > = 2 μg/mL strains (5% overall, was detected in serotypes (descending order 23B, 17F, 9N, 6B, 6A, 11A, 23F, and in 10 additional serotypes including 6C. Conclusion Pneumococcal carriage remains high (~80% in this vaccinated population. Uptake of both pneumococcal vaccines increased, and carriage was reduced between 2003 and 2005. Predominant serotypes in combined

  18. Live, Attenuated Influenza A H5N1 Candidate Vaccines Provide Broad Cross-Protection in Mice and Ferrets

    Science.gov (United States)

    Mills, Kimberly L; Jin, Hong; Duke, Greg; Lu, Bin; Luke, Catherine J; Murphy, Brian; Swayne, David E; Kemble, George; Subbarao, Kanta

    2006-01-01

    Background Recent outbreaks of highly pathogenic influenza A H5N1 viruses in humans and avian species that began in Asia and have spread to other continents underscore an urgent need to develop vaccines that would protect the human population in the event of a pandemic. Methods and Findings Live, attenuated candidate vaccines possessing genes encoding a modified H5 hemagglutinin (HA) and a wild-type (wt) N1 neuraminidase from influenza A H5N1 viruses isolated in Hong Kong and Vietnam in 1997, 2003, and 2004, and remaining gene segments derived from the cold-adapted (ca) influenza A vaccine donor strain, influenza A/Ann Arbor/6/60 ca (H2N2), were generated by reverse genetics. The H5N1 ca vaccine viruses required trypsin for efficient growth in vitro, as predicted by the modification engineered in the gene encoding the HA, and possessed the temperature-sensitive and attenuation phenotypes specified by the internal protein genes of the ca vaccine donor strain. More importantly, the candidate vaccines were immunogenic in mice. Four weeks after receiving a single dose of 106 50% tissue culture infectious doses of intranasally administered vaccines, mice were fully protected from lethality following challenge with homologous and antigenically distinct heterologous wt H5N1 viruses from different genetic sublineages (clades 1, 2, and 3) that were isolated in Asia between 1997 and 2005. Four weeks after receiving two doses of the vaccines, mice and ferrets were fully protected against pulmonary replication of homologous and heterologous wt H5N1 viruses. Conclusions The promising findings in these preclinical studies of safety, immunogenicity, and efficacy of the H5N1 ca vaccines against antigenically diverse H5N1 vaccines provide support for their careful evaluation in Phase 1 clinical trials in humans. PMID:16968127

  19. Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets.

    Directory of Open Access Journals (Sweden)

    Amorsolo L Suguitan

    2006-09-01

    Full Text Available Recent outbreaks of highly pathogenic influenza A H5N1 viruses in humans and avian species that began in Asia and have spread to other continents underscore an urgent need to develop vaccines that would protect the human population in the event of a pandemic.Live, attenuated candidate vaccines possessing genes encoding a modified H5 hemagglutinin (HA and a wild-type (wt N1 neuraminidase from influenza A H5N1 viruses isolated in Hong Kong and Vietnam in 1997, 2003, and 2004, and remaining gene segments derived from the cold-adapted (ca influenza A vaccine donor strain, influenza A/Ann Arbor/6/60 ca (H2N2, were generated by reverse genetics. The H5N1 ca vaccine viruses required trypsin for efficient growth in vitro, as predicted by the modification engineered in the gene encoding the HA, and possessed the temperature-sensitive and attenuation phenotypes specified by the internal protein genes of the ca vaccine donor strain. More importantly, the candidate vaccines were immunogenic in mice. Four weeks after receiving a single dose of 10(6 50% tissue culture infectious doses of intranasally administered vaccines, mice were fully protected from lethality following challenge with homologous and antigenically distinct heterologous wt H5N1 viruses from different genetic sublineages (clades 1, 2, and 3 that were isolated in Asia between 1997 and 2005. Four weeks after receiving two doses of the vaccines, mice and ferrets were fully protected against pulmonary replication of homologous and heterologous wt H5N1 viruses.The promising findings in these preclinical studies of safety, immunogenicity, and efficacy of the H5N1 ca vaccines against antigenically diverse H5N1 vaccines provide support for their careful evaluation in Phase 1 clinical trials in humans.

  20. Molecular characterization of influenza viruses circulating in Northern Italy during two seasons (2005/2006 and 2006/2007) of low influenza activity.

    Science.gov (United States)

    Pariani, Elena; Amendola, Antonella; Zappa, Alessandra; Bianchi, Silvia; Colzani, Daniela; Anselmi, Giovanni; Zanetti, Alessandro; Tanzi, Elisabetta

    2008-11-01

    The influenza activity and circulation of influenza viruses in Lombardy (the most populous Italian region) were observed during two consecutive seasons (2005/2006 and 2006/2007) characterized by low influenza activity by the Italian Influenza Surveillance Network. The molecular characteristics of circulating viruses were analyzed to evaluate the introduction of new variants and emergence of vaccine-escape viruses. In both seasons, the epidemic in Lombardy was sustained almost exclusively by influenza A viruses, accounting for 80.5% and 93.6% of total detections, respectively, and the co-circulation of A/H3 viruses belonging to distinct phylogenetic groups was observed. The A/H1N1 viruses isolated during the 2005/2006 season were closely related to A/New Caledonia/20/99, while the hemagglutinin (HA) sequences of the A/H1N1 viruses from the 2006/2007 season exhibited a greater diversity. These viruses were A/Solomon Islands/3/2006-like and showed several variants. All B isolates were similar to B/Malaysia/2506/2004 belonging to the B/Victoria/2/87-lineage. Influenza B virus was the dominant virus in Europe in the 2005/2006 season and accounted for the 20% of total detections in Lombardy. Overall, the viruses studied presented heterogeneity in their HA sequences suggesting the circulation of a miscellaneous set of variants during the two seasons notwithstanding the medium-low activity of influenza. The importance of virological surveillance of influenza viruses is recognized widely and the molecular characterization of the viruses, especially in vaccinated subjects, is of particular importance to evaluate the introduction and circulation of new variants. 2008 Wiley-Liss, Inc.

  1. Academic Training: 2004 - 2005 ACADEMIC TRAINING PROGRAMME

    CERN Multimedia

    Françoise Benz

    2004-01-01

    1st Term - 01 October to 17 December 2004 REGULAR LECTURE PROGRAMME New Trends in Fusion Research by A. Fasoli, EPFL, Lausanne, CH 11, 12, 13 October Physics at e+e- linear collider by K. Desch, DESY, Hamburg, D 15, 16, 17, 18, 19 November LECTURE SERIES FOR POSTGRADUATE STUDENTS Standard Model by R. Barbieri, CERN-PH-TH 6, 7, 8, 9 10 December The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc) will be published in the CERN Bulletin, the WWW, and by notices before each term and for each series of lectures. ENSEIGNEMENT ACADEMIQUE ACADEMIC TRAINING Françoise Benz 73127 academic.training@cern.ch If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form a...

  2. Neonate exposure to thimerosal mercury from hepatitis B vaccines.

    Science.gov (United States)

    Dórea, José G; Marques, Rejane C; Brandão, Katiane G

    2009-08-01

    Infant exposure to ethylmercury (EtHg) has not only increased but is starting earlier as a result of the current immunization schedule that uses thimerosal-containing vaccines (TCVs). Although vaccination schedule varies considerably between countries, infants in less-developed countries continue to be exposed to EtHg derived from more affordable TCVs. We studied the exposure of newborns to EtHg from hepatitis B vaccines; hospital records (21,685) were summarized for the years 2001 to 2005 regarding date of birth, vaccination date, and birth weight. Most of the vaccinations occurred in the first 24 hours postdelivery; over the 5 years, there was an increase in vaccinations within hours of birth (same day), from 7.4% (2001) to 87.8% (2005). Nearly 94.6% of infants are now being vaccinated within the first 24 hours. Range of mercury exposure spread from 4.2 to 21.1 microg mercury/kg body weight for those receiving TCVs with the highest thimerosal concentration; these exposure levels are conservative for 2% of children receiving vaccines within 2 to 3 postnatal days, when they are still going through physiological postnatal weight loss. Because of the particular timing (transitioning from in utero to ex utero metabolism) and specific aspects of exposure (i.e., parenteral mode, bypassing gastroenteric barriers) and dose (related to vaccine manufacturer and with variation in birth weight), this study reveals critical issues that can modulate toxicokinetics and toxicodynamics of organomercurials in neonates.

  3. G8 global partnership. 2004-2005-2006 activity report

    International Nuclear Information System (INIS)

    2007-01-01

    The Global Partnership Against the Spread of Weapons and Materials of Mass Destruction was launched by the heads of state and government of the G8 at the G8 summit in Kananaskis in June 2002. Fourteen other countries have since joined this G8 initiative. The aim of this partnership is to 'prevent terrorists, or those who harbor them, from acquiring or developing nuclear, chemical radiological and biological weapons, missiles, and related materials, equipment and technology'. Within the framework of the Partnership, the participants have agreed to support cooperation projects, starting with Russia, to promote non-proliferation, disarmament, the fight against terrorism and nuclear safety. The destruction of chemical weapons, the dismantling of decommissioned nuclear submarines, the disposal of fissile materials and the employment of former weapons scientists are among the priority concerns expressed. Ukraine has also been a beneficiary of this partnership since 2004. The participants in this initiative have agreed to contribute up to 20 billion dollars (up to 750 million euros from France) to support these projects over a period of ten years from 2002. A group of experts from the G8 on the Global Partnership (the GPWG = Global Partnership Working Group) meets regularly and gives an account of the progress made with this initiative in its annual report to the G8. These annual reports are published at the G8 summits. This document is the 2004 to 2006 activity report of the G8 global partnership

  4. Powernext futures statistics - August 31, 2005

    International Nuclear Information System (INIS)

    2005-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the August 31, 2005 update of Powernext Futures TM statistics: year, quarter and month contracts for August 2005, base-load and peak-load contracts overview from March 2005 to August 2005 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity in August 2005 (average bid ask spread and availability). (J.S.)

  5. Powernext futures statistics - December 31, 2005

    International Nuclear Information System (INIS)

    2005-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the December 31, 2005 update of Powernext Futures TM statistics: year, quarter and month contracts for December 2005, base-load and peak-load contracts overview from July 2005 to December 2005 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity in December 2005 (average bid ask spread and availability). (J.S.)

  6. Powernext futures statistics - November 30, 2005

    International Nuclear Information System (INIS)

    2005-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the November 30, 2005 update of Powernext Futures TM statistics: year, quarter and month contracts for November 2005, base-load and peak-load contracts overview from June 2005 to November 2005 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity in November 2005 (average bid ask spread and availability). (J.S.)

  7. Mexico introduces pentavalent vaccine.

    Science.gov (United States)

    1999-08-01

    Combination vaccines have been introduced in Mexico. The national immunization program has incorporated the measles-mumps-rubella (MMR) vaccines in 1998, and the pentavalent vaccine in 1999. The two categories of antigen composition in combination vaccines are: 1) multiple different antigenic types of a single pathogen, such as the 23 valent pneumococcal polysaccharide vaccine, and 2) antigens from different pathogens causing different diseases, such as the DPT and MMR vaccines. Pentavalent vaccines are included in the second category. The vaccine protects against diphtheria, tetanus, pertussis, hepatitis B, and other diseases produced by Haemophilus influenzae type b (Hib). Combined diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenza type b (DTP-HB/Hib) vaccine has been distributed to 87% of Mexican children under 1 year of age. Over 800,000 doses of pentavalent vaccine have been administered.

  8. Annual Report 2005

    Energy Technology Data Exchange (ETDEWEB)

    Swiboda, G [Institute of Atomic Energy, Otwock-Swierk (Poland)

    2006-07-01

    The Annual Report of the Institute of Atomic Energy describes the results of the research activities carried out in 2005. The document consist of seven parts: General Information; Operation and safety of MARIA reactor; Radiological protection and dosimetry; Nuclear Technology in Energy Generation; Solid State Physics; Nuclear techniques in Health and Environment Protection management of Hazards and in last section the list of published in 2004 papers, conferences, seminars, workshops, research projects and educational activities are presented.

  9. Annual Report 2005

    International Nuclear Information System (INIS)

    Swiboda, G.

    2006-01-01

    The Annual Report of the Institute of Atomic Energy describes the results of the research activities carried out in 2005. The document consist of seven parts: General Information; Operation and safety of MARIA reactor; Radiological protection and dosimetry; Nuclear Technology in Energy Generation; Solid State Physics; Nuclear techniques in Health and Environment Protection management of Hazards and in last section the list of published in 2004 papers, conferences, seminars, workshops, research projects and educational activities are presented

  10. Publications 2004

    Directory of Open Access Journals (Sweden)

    2005-03-01

    Full Text Available Fabienne Blaise- F. Blaise, P. Judet de La Combe et Ph. Rousseau (éds. : Le Métier du mythe. Lectures d'Hésiode (Villeneuve d'Ascq, PUS, 1996 - traduction chinoise à paraître aux éditions Huaxia Publishing House of China, Pékin, en 2005.Jean Bollack- La Muerte de Antigona. La tragedia de Creonte. Traduction en espagnol de La Mort d'Antigone (Paris, PUF, 1999 par Arnaud Pons et de Xavier Riu, Arena Libros, coll. Tempo al Tempo, Madrid 2004,  144 p. -  Sentido contra sentido. ¿ Como se lee ?...

  11. Draft Budget of the Organization for the Fifty-First Financial Year 2005

    CERN Document Server

    2004-01-01

    A sa réunion du 15 septembre 2004 , le Comité des finances a recommandé au Conseil d'approuver le projet préliminaire de budget 2005 aux prix de 2004. La présente version tient compte des transferts du budget 2004 présentés dans le document "Budget 2004 - Transferts et dépassements de crédits" , du prélèvement dans la réserve pour imprévus pour le LHC indiqué dans le document "Réserve pour imprévus pour le LHC" et de divers ajustements mineurs. En conséquence, il est demandé au Comité des finances de recommander au Conseil d'approuver les modifications par rapport au projet préliminaire de budget 2005 présentées dans les tableaux de l'annexe 1.

  12. Technical Cooperation Report for 2004. Report by the Director General

    International Nuclear Information System (INIS)

    2005-08-01

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  13. Technical Cooperation Report for 2004. Report by the Director General

    International Nuclear Information System (INIS)

    2005-08-01

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  14. Technical Cooperation Report for 2004. Report by the Director General

    International Nuclear Information System (INIS)

    2005-08-01

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  15. Technical Cooperation Report for 2004. Report by the Director General

    International Nuclear Information System (INIS)

    2005-07-01

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  16. Technical Cooperation Report for 2004. Report by the Director General

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-15

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  17. Technical Cooperation Report for 2004. Report by the Director General

    International Nuclear Information System (INIS)

    2005-08-01

    The Technical Cooperation Report for 2004 highlights activities and achievements of the technical cooperation programme for the past year. During 2004, the Secretariat finalized the technical cooperation programme for the 2005-2006 biennium, which was approved by the Board of Governors in November 2004. A revised project appraisal process was carried out for the 2005-2006 programme, which yielded additional information regarding government commitment, national capabilities and project performance indicators and outcomes. Included in the 2005-2006 biennium is a strengthened programme for upgrading radiation protection infrastructure. The Secretariat used the experience of the past ten years, as well as conclusions from evaluations, to create a programme that would build upon the successes and lessons learned to provide the safe use of nuclear technology with well-regulated infrastructures. Activities carried out in 2004 built upon previous achievements through national and regional projects in many thematic areas. The programme continued to reinforce the capacity for cancer diagnosis and therapy by providing training and expertise and supporting the procurement of equipment. Consistent support for surveillance techniques using nuclear technology is helping to fight trans-boundary animal diseases, and is leading to countries becoming rinderpest-free. The Secretariat continued to provide expertise and support to assist with the repatriation of highly enriched uranium reactor fuel to the country of origin. The development of partnerships with other United Nations organizations, as well as non-governmental organizations, continues to be of great importance to the technical cooperation programme. In 2004, for example, a memorandum of understanding was signed with the Regional Office for Africa (AFRO) of the World Health Organization (WHO) to support the improvement of health conditions and to raise standards of health in the region. Extrabudgetary resources reached more

  18. Preventive and therapeutic application of Hib and pneumococcal vaccines among children, who are prone to frequent and prolonged recurrent otites media

    Directory of Open Access Journals (Sweden)

    T.I. Garashchenko

    2006-01-01

    Full Text Available THE AIM OF THE RESEARCH WAS TO ASSESS THE CLINIC EFFECTIVENESS OF A COMBINED APPLICATION OF SUCH VACCINES AS: ACTBHIB AND PNEUMO 23 (SANOFI PASTEUR, FRANCE IN CHILDREN, WHO ARE PRONE TO FREQUENT AND PROLONGED RECURRENT OTITES MEDIA. DURING 2004 AND 2005, 153 CHILDREN AGED BETWEEN 2 AND 12 YEARS OLD WERE IMMUNIZED AND OBSERVED. THE CONTROL GROUP WAS MADE UP OF 30 CHILDREN, WHOSE PARENTS REFUSED TO PARTICIPATE IN VACCINATION. THE CHILDREN OF BOTH GROUPS WERE COMPARABLE. THE FINDINGS OF THE RESEARCH SHOWED HIGH PREVENTIVE EFFECTIVENESS OF THE COMBINED IMMUNIZATION, WHICH PROVIDED A 3BFOLD REDUCTION OF ACUTE RESPIRATORY INFECTIONS AND RECURRENT OTITES, A REDUCTION OF ANTIBACTERIAL THERAPY PRESCRIPTION BY MORE THAN 8 TIMES AND A REDUCTION OF H. INFLUENZAE AND PNEUMOCOCCUS CARRIAGE BY 9 TIMES. IN THE GROUP OF IMMUNIZED CHILDREN, THE RESEARCHERS OBSERVED A REDUCTION OF ADENOID VEGETATION AUXESIS, RECOVERY OF AUDITORY TUBE PASSABILITY IN 85% OF CASES ALONG WITH THE PRESSURE NORMALIZATION IN TYMPANIC CAVITY. THEREFORE, THESE FINDINGS ALLOW TO EXPAND INDICATIONS FOR THE COMBINED IMMUNIZATION BY VACCINES AGAINST HIBB AND PNEUMOCOCCAL INFECTION, AS WELL AS TO PURSUE IMMUNIZATION WITH PNEUMO 23 AND ACT-HIB VACCINES BY PNEUMO 23 AND ACTBHIB IN CHILDREN, WHO ARE PRONE TO FREQUENT AND PROLONGED RECURRENT OTITES MEDIA AND ADENOID VEGETATION AUXESIS.KEY WORDS: VACCINATION, CHILDREN, H. INFLUENZAE, S. PNEUMONIAE, OTITES MEDIA.

  19. CERN car stickers 2005

    CERN Multimedia

    Reception and Access Control Service - TS Department

    2004-01-01

    Please note that the car stickers for 2005 are now available. If you have not received the new one by internal mail, you should go along in person to the Registration Service (bldg. 55 - 1st floor), open non-stop from 7:30 to 16:30, taking with you your 2004 sticker and the log-book of your vehicle. Thank you for your collaboration. Reception and Access Control Service - TS Department.

  20. Prevalence and trend in the use of hospital-based standing orders programs for influenza and pneumococcal vaccination.

    Science.gov (United States)

    Pentakota, Sri Ram; Halperin, William

    2007-08-01

    In 2002, federal regulations authorized the use of standing orders programs (SOPs) for promoting influenza and pneumococcal vaccination. In 2003, the New Jersey Hospital Association conducted a demonstration project illustrating the efficacy of SOPs, and the state health department informed healthcare facilities of their benefits. We describe the prevalence of reported use of SOPs in New Jersey hospitals in 2003 and 2005 and identify hospital characteristics associated with the use of SOPs. A survey was mailed to the directors of infection control at 117 New Jersey hospitals during the period from January to May 2005 (response rate, 90.6%). Data on hospital characteristics were obtained from hospital directories and online resources. The prevalence of use of SOPs for influenza vaccination was 50% (95% confidence interval [CI], 40.1%-59.9%) in 2003, and it increased to 78.3% (95% CI, 69.2%-85.7%) in 2005. The prevalence of SOP use for pneumococcal vaccination was similar. In 2005, the reported rate of use of SOPs for inpatients (influenza vaccination, 76.4%; pneumococcal vaccination, 75.5%) was significantly higher than that for outpatients (influenza vaccination, 9.4%; pneumococcal vaccination, 8.5%). Prevalence ratios for SOP use comparing acute care and non-acute care hospitals were 1.71 (95% CI, 1.2-2.5) for influenza vaccination SOPs and 1.8 for (95% CI, 1.2-2.7) pneumococcal vaccination SOPs. Acute care hospitals with a ratio of admissions to total beds greater than 36.7 reported greater use of SOPs for pneumococcal vaccination, compared with those that had a ratio of less than 36.7. The increase in the prevalence of reported use of SOPs among New Jersey hospitals in 2005, compared with 2003, was contemporaneous with SOP-related actions taken by the federal government, the state government, and the New Jersey Hospital Association. Opportunities persist for increased use of SOPs among non-acute care hospitals and for outpatients.

  1. International Atomic Energy Agency publications. Publications catalogue 2006 including full details of publications published in 2004-2005 and forthcoming in 2006 and a stocklist of publications published in 2002-2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-15

    This Publications Catalogue lists all sales publications of the IAEA published in 2004, 2005 and forthcoming in 2006. Most IAEA publications are issued in English, some are also available in Arabic, Chinese, French, Russian or Spanish. This is indicated at the bottom of the book entry. A complete listing of all IAEA priced publications is available on the IAEA's web site: http://www.iaea.org/books.

  2. International Atomic Energy Agency publications. Publications catalogue 2006 including full details of publications published in 2004-2005 and forthcoming in 2006 and a stocklist of publications published in 2002-2003

    International Nuclear Information System (INIS)

    2006-03-01

    This Publications Catalogue lists all sales publications of the IAEA published in 2004, 2005 and forthcoming in 2006. Most IAEA publications are issued in English, some are also available in Arabic, Chinese, French, Russian or Spanish. This is indicated at the bottom of the book entry. A complete listing of all IAEA priced publications is available on the IAEA's web site: http://www.iaea.org/books

  3. De controle van collectieve leidingwaterinstallaties in 2005

    NARCIS (Netherlands)

    Dik HHJ; Versteegh A; IMD

    2007-01-01

    The Inspection of collective tapwater installations in 2005. Progress and findings. Since 2004 the drinking water companies in the Netherlands have, by law, had the task of inspecting connected tapwaterinstallations for both the risk of contamination of the public mains system and the risks posed

  4. I-NERI 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2004-01-01

    The International Nuclear Energy Research Initiative (I-NERI) supports the National Energy Policy by conducting research to advance the state of nuclear science and technology in the United States (U.S.). I-NERI sponsors innovative scientific and engineering research and development (R&D) in cooperation with participating countries. The R&D research performed under the I-NERI umbrella addresses the key issues affecting the future of nuclear energy and its global deployment. I-NERI research is directed towards improving cost performance, increasing proliferation resistance, enhancing safety, and improving the waste management of future nuclear energy systems. This I-NERI 2004 Annual Report serves to inform interested parties on the program's organization, progress of the collaborative research projects, and future planning for the program. The report covers the four years of I-NERI activity since the program's inception in fiscal year (FY) 2001. The motivation and series of events that led to the creation of the I-NERI program are discussed in Section 2. The participating countries in current I-NERI collaborative agreements are also presented. Section 3 presents an overview of the I-NERI goals and objectives, a work scope summary for the collaborative projects, and a summary of research project awards through the end of FY 2004. It also includes FY 2005 accomplishments and planned FY 2005 activities. A summary of programmatic accomplishments is presented in Section 4. Also included is a summary of new and existing projects, an overview of the I-NERI program funding, and the new collaborations anticipated in FY 2005. The R&D work scope for current I-NERI collaborative projects with Canada, France, Japan, the Organization for Economic Cooperation and Development/Nuclear Energy Agency (OECD/NEA), and the Republic of Korea are presented in Sections 5 through 9, respectively. For each participating country, an index of projects and a summary of FY 2004

  5. AREVA - first half 2005 sales figures; AREVA - chiffre d'affaires du 1. semestre 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    First half 2005 sales for the AREVA group were up 1.1% to 5,396 million euros and 2.6% like-for-like, compared with 5,339 million euros for the same period in 2004.The change in foreign exchange rates had a negative impact of nearly (34) million euros between these two periods, which was much less than between the first half of 2003 and the same period in 2004. Sales are up 1.1% compared with the first half of 2004 (up 2.6% like-for-like); the euros (17.3) M impact of IFRS adoption is limited to the Front End division; Energy is up: Nuclear Power: up 4.4% (up 5.5% like-for-like), driven by the Front End and Reactors and Services divisions; T and D: down 3.9% (-2.1% like-for-like) due to the one time peak observed in early 2004; Connectors sales are stable (+0.3% like-for-like): Automotive performed well, while the communication market continued to be a difficult one.

  6. Research on Captive Broodstock Programs for Pacific Salmon, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Berejikian, Barry A. (National Marine Fisheries Service)

    2005-11-01

    The success of captive broodstock programs depends on high in-culture survival, appropriate development of the reproductive system, and the behavior and survival of cultured salmon after release, either as adults or juveniles. Continuing captive broodstock research designed to improve technology is being conducted to cover all major life history stages of Pacific salmon. Accomplishments detailed in this report and those since the last project review period (FY 2003) are listed below by major objective. Objective 1: (i) Developed tools for monitoring the spawning success of captively reared Chinook salmon that can now be used for evaluating the reintroduction success of ESA-listed captive broodstocks in their natal habitats. (ii) Developed an automated temperature controlled rearing system to test the effects of seawater rearing temperature on reproductive success of Chinook salmon. Objective 2: (i) Determined that Columbia River sockeye salmon imprint at multiple developmental stages and the length of exposure to home water is important for successful imprinting. These results can be utilized for developing successful reintroduction strategies to minimize straying by ESA-listed sockeye salmon. (ii) Developed behavioral and physiological assays for imprinting in sockeye salmon. Objective 3: (i) Developed growth regime to reduce age-two male maturation in spring Chinook salmon, (ii) described reproductive cycle of returning hatchery Snake River spring Chinook salmon relative to captive broodstock, and (iii) found delays in egg development in captive broodstock prior to entry to fresh water. (iv) Determined that loss of Redfish Lake sockeye embryos prior to hatch is largely due to lack of egg fertilization rather than embryonic mortality. Objective 4 : (i) Demonstrated safety and efficacy limits against bacterial kidney disease (BKD) in fall Chinook of attenuated R. salmoninarum vaccine and commercial vaccine Renogen, (ii) improved prophylactic and therapeutic

  7. National Trends of Antiparkinsonism Treatment in Taiwan: 2004–2011

    Directory of Open Access Journals (Sweden)

    Weng-Ming Liu

    2016-01-01

    Full Text Available Background. Several guidelines for Parkinson’s disease (PD management were recently updated. We examined temporal trends for antiparkinsonism drugs in Taiwan. Methods. Antiparkinsonism prescriptions, including levodopa, ergot/nonergot dopamine agonists (DAs, amantadine, selegiline, entacapone, and anticholinergics, were identified in the Taiwan National Health Insurance Database from 2004 to 2011. Time trend analyses were estimated assuming Poisson distribution. Results. A total of 19,302 PD patients in 2004 and 41,606 PD patients in 2011 were analyzed. Antiparkinsonism prescriptions increased significantly from 187,137 in 2004 to 414,587 in 2011. Levodopa monotherapy or combination therapy was the mainstay. Levodopa monotherapy comprised 37.4% of prescriptions in 2004 and 44.2% in 2011, with an annual increase rate of 18.14%. There was a substantially increasing trend of DA prescriptions, which were higher in younger-aged patients (<60 years than in older-aged group (p=0.0006. Among combination therapy, DA combined with levodopa or other antiparkinsonism medications became the main combinations for younger-aged patients after 2009. After 2005, the proportion of ergot DA usage markedly decreased and PD patients using nonergot DA increased. Conclusions. Levodopa was the major treatment from 2004 to 2011. There was a steeply increased trend of DA use, especially in younger-aged patients. Nonergot agents comprised the major DA group after 2005.

  8. Nuclear power 2005: European report

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    In 2005, nuclear power plants were operated and/or built in eighteen European countries. Thirteen of these countries are members of EU-25. Five of the ten countries joining the European Union on May 1, 2004 operate nuclear power stations. A total of 204 power reactors with a gross power of 181,030 MWe and a net power of 171,8479 MWe were in operation at the end of the year. In 2005, no nuclear power plant was commissioned. Two nuclear power plants were decommissioned in Europe in the course of 2005. In Germany the Obrigheim NPP and in Sweden the Barsebaeck 2 NPP have been permanently shut down due to political decisions. As a result of ongoing technical optimization in some plants, involving increases in reactor power or generator power as well as commissioning of plants of higher capacity, nuclear generating capacity increased by approx. 1.6 GW. In late 2005, five nuclear generating units were under construction in Finland (1), Romania (1), and Russia (3). 148 nuclear power plants were operated in thirteen states of the European Union (EU-25). They had an aggregate gross power of 137,023 MWe and a net power of 130,415 MWe, generating approx. 970 billion gross kWh of electricity in 2005, thus again contributing some 31% to the public electricity supply in the EU-25. In largest share of nuclear power in electricity generation is found in France (80%), followed by 72% in Lithuania, 55% in the Slovak Republic, 55% in Belgium, and 51% in Ukraine. In several countries not operating nuclear power plants of their own, such as Italy, Portugal, and Austria, nuclear power makes considerable contributions to public electricity supply as a result of electricity imports. (All statistical data in the country report apply to 2004 unless indicated otherwise. This is the year for which sound preliminary data are currently available for the states listed.) (orig.)

  9. Status and prospects for gas cooled reactor fuels. Proceedings of two IAEA meetings held in June 2004 and June 2005

    International Nuclear Information System (INIS)

    2009-04-01

    Recently, efforts to develop high temperature gas cooled reactors with an aim to building futuristic nuclear energy systems with advanced nuclear fuel cycles in the context of the Generation IV International Forum have increased significantly. In addition, several development projects are ongoing, focusing on the burning of weapons grade plutonium, including civil plutonium and other transuranic elements using the 'deep-burn concept', or 'inert matrix fuels', especially in the form of coated particles in gas cooled reactor systems. There is also considerable global interest in developing 'nuclear hydrogen' energy systems using high temperature gas cooled reactors. Apart from these developments, the value of preserving the large technology base developed in Germany, the United Kingdom and the United States of America, as well as information developed in other countries, has also been a subject of interest to the IAEA. At the second annual meeting of the 'technical working group on nuclear fuel cycles options and spent fuel management' (TWG-NFCO), held in Vienna from 28-30 May 2003, it was recommended to hold a technical meeting on Current Status and Future Prospects of Gas Cooled Reactor Fuels. The meeting should cover the technological progress that has been made in the last three years and plan future fabrication and qualification facilities for GCR/HTR fuel. TWG-NFCO considered it timely that this progress should be presented and discussed in the interested community. Recognizing the numerous activities being pursued in many Member States, the IAEA convened the technical meeting on this topic in June 2004 in Vienna. Consequently, an update meeting was held in June 2005, which was hosted by the Kharkov Institute of Physics and Technology of Ukraine to review and integrate the latest developments. This publication combines the results of the technical meeting of June 2004 and the meeting of June 2005. The proceedings presented here contain 25 in depth papers on the

  10. The main fiscal dispositions in the domain of energy and mineral raw materials as foreseen by the 2005 finances law and by the last 2004 amended law

    International Nuclear Information System (INIS)

    2004-01-01

    This short paper summarizes in tables the main changes made in the 2005 French finances law and in the 2004 amended law about: the domestic tax on petroleum products (TIPP), the general tax on polluting activities (TGAP), the bio-fuel production units, the tax credits for the implementation of renewable energies in dwellings, the domestic tax on natural gas consumptions (TICGN) for greenhouse owners, the European harmonization of the added-value tax (TVA), the taxes on companies (IS), and the electric utility charges (CSPE). (J.S.)

  11. Chemical composition of ambient PM2. 5 over China and relationship to precursor emissions during 2005-2012

    Science.gov (United States)

    Geng, Guannan; Zhang, Qiang; Tong, Dan; Li, Meng; Zheng, Yixuan; Wang, Siwen; He, Kebin

    2017-07-01

    In this work, we presented the characteristics of PM2. 5 chemical composition over China for the period of 2005-2012 by synthesis of in situ measurement data collected from literatures and satellite-based estimates using aerosol optical depth (AOD) data and the GEOS-Chem chemical transport model. We revealed the spatiotemporal variations in PM2. 5 composition during 2005-2012 and investigated the driving forces behind the variations by examining the changes in precursor emissions using a bottom-up emission inventory. Both in situ observations and satellite-based estimates identified that secondary inorganic aerosols (i.e., sulfate, nitrate, and ammonium; SNA) ranked as the highest fraction of dust-free PM2. 5 concentrations, followed by organic matter (OM) and black carbon (BC). For instance, satellite-based estimates found that SNA, OM, and BC contributed to 59, 33, and 8 %, respectively, of national population-weighted mean dust-free PM2. 5 concentrations during 2005-2012. National population-weighted mean PM2. 5 concentration increased from 63.9 µg m-3 in 2005 to 75.2 µg m-3 in 2007 and subsequently decreased to 66.9 µg m-3 from 2007 to 2012. Variations in PM2. 5 concentrations are mainly driven by the decrease in sulfate and the increase in nitrate. Population-weighted mean sulfate concentration decreased by 2.4 % yr-1 during 2005-2012 (from 14.4 to 12.9 µg m-3), while population-weighted mean nitrate concentration increased by 3.4 % yr-1 during 2005-2012 (from 9.8 to 12.2 µg m-3), largely offsetting the decrease in sulfate concentrations. By examining the emission data from the Multi-resolution Emission Inventory for China (MEIC), we found that the changes in sulfate and nitrate concentrations were in line with the decrease in SO2 emissions and the increase in NOx emissions during the same period. The desulfurization regulation in power plants enforced around 2005 has been the primary contributor to the SO2 emission reduction since 2006. In contrast

  12. Nuclear power plants: 2005 atw compact statistics

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    Nuclear power plants were available for power supply and under construction, respectively, in 32 countries of the world as per end of 2005. A total of 444 nuclear power plants, i.e. three plants more than at the end of 2004, with an aggregate gross power of approx. 389 GWe and an aggregate net power of 370 GWe, respectively, were in operation in 31 countries. The available capacity of nuclear power plants increased by some 4,5 GWe as a result of the capacities added by the four newly commissioned units of Higashidori 1 (Japan), Shika 2 (Japan), Tarapur 4 (India), and Tianwan 1 (China). In addition, unit A-1 of the Pickering nuclear power station in Canada, with 825 MWe, was restarted after a downtime of several years. Two plants were decommissioned for good in 2005: Obrigheim in Germany, and Barsebaeck 2 in Sweden. 23 nuclear generating units, i.e. one unit more than in late 2004, with an aggregate gross power of approx. 19 GWe were still under construction in nine countries by late 2005. In Pakistan, construction of a new project, Chasnupp 2, was started; in China, construction was begun of two units, Lingao Phase 2, units 3 and 4, and in Japan, the Shimane 3 generating unit is being built. (orig.)

  13. Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish.

    Science.gov (United States)

    Heath, Candice; Gillen, Christine M; Chrysanthopoulos, Panagiotis; Walker, Mark J; Barnes, Andrew C

    2016-09-25

    Streptococcus iniae causes septicaemia and meningitis in marine and freshwater fish wherever they are farmed in warm-temperate and tropical regions. Although serotype specific, vaccination with bacterins (killed bacterial cultures) is largely successful and vaccine failure occurs only occasionally through emergence of new capsular serotypes. Previously we showed that mutations in vaccine escapes are restricted to a limited repertoire of genes within the 20-gene capsular polysaccharide (cps) operon. cpsG, a putative UDP-galactose 4-epimerase, has three sequence types based on the insertion or deletion of the three amino acids leucine, serine and lysine in the substrate binding site of the protein. To elucidate the role of cpsG in capsular polysaccharide (CPS) biosynthesis and capsular composition, we first prepared isogenic knockout and complemented mutants of cpsG by allelic exchange mutagenesis. Deletion of cpsG resulted in changes to colony morphology and cell buoyant density, and also significantly decreased galactose content relative to glucose in the capsular polysaccharide as determined by GC-MS, consistent with epimerase activity of CpsG. There was also a metabolic penalty of cpsG knockout revealed by slower growth in complex media, and reduced proliferation in whole fish blood. Moreover, whilst antibodies raised in fish against the wild type cross-reacted in whole cell and cps ELISA, they did not cross-opsonise the mutant in a peripheral blood neutrophil opsonisation assay, consistent with reported vaccine escape. We have shown here that mutation in cpsG results in altered CPS composition and this in turn results in poor cross-opsonisation that explains some of the historic vaccination failure on fish farms in Australia. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

  14. Robustness of networks against propagating attacks under vaccination strategies

    International Nuclear Information System (INIS)

    Hasegawa, Takehisa; Masuda, Naoki

    2011-01-01

    We study the effect of vaccination on the robustness of networks against propagating attacks that obey the susceptible–infected–removed model. By extending the generating function formalism developed by Newman (2005 Phys. Rev. Lett. 95 108701), we analytically determine the robustness of networks that depends on the vaccination parameters. We consider the random defense where nodes are vaccinated randomly and the degree-based defense where hubs are preferentially vaccinated. We show that, when vaccines are inefficient, the random graph is more robust against propagating attacks than the scale-free network. When vaccines are relatively efficient, the scale-free network with the degree-based defense is more robust than the random graph with the random defense and the scale-free network with the random defense

  15. Umatilla River Subbasin Fish Habitat Improvement Program, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    St. Hilaire, Danny R. (Oregon Department of Fish and Wildlife, Pendleton, OR)

    2006-02-01

    This annual report is in fulfillment of contractual obligations with Bonneville Power Administration (BPA), which is the funding source for the Oregon Department of Fish and Wildlife's (ODFW), Umatilla River Subbasin Fish Habitat Improvement Program (Program). The Program works cooperatively with private landowners to develop long-term restoration, under which, passive and active Habitat Improvement Projects are conducted. Historically, projects have included livestock exclusion fencing (passive restoration) to protect riparian habitats, along with the installation of instream structures (active restoration) to address erosion and improve fish habitat. In recent years, the focus of active restoration has shifted to bioengineering treatments and, more recently, to channel re-design and reconstruction aimed at improving fish habitat, by restoring stable channel function. This report provides a summary of Program activities for the 2004 calendar year (January 1 through December 31, 2004), within each of the four main project phases, including: (1) Implementation--Pre-Work, (2) Implementation--On Site Development, (3) Operation and Maintenance, and (4) Monitoring and Evaluation. This report also summarizes Program Administrative, Interagency Coordination, and Public Education activities.

  16. [Effects of self-adapting G-DRG system 2004 to 2006 on in-patient services payment in pediatric hematology and oncology patients of a university hospital].

    Science.gov (United States)

    Christaras, A; Schaper, J; Strelow, H; Laws, H-J; Göbel, U

    2006-01-01

    Reimbursement of inpatient treatment by daily constant charges is replaced by diagnosis- and procedure-related group system (G-DRG) in German acute care hospitals excerpt for psychiatry since 2004. Re-designs of G-DRG system were undertaken in 2005 and 2006. Parallel to implementation requirement- and resource-based self-adjustment of this new reimbursement system has been established by law. Adjustments performed in 2005 and 2006 are examined with respect to their effect on reimbursements in treatments of children with oncological, hematological, and immunological diseases. An unchanged population of 349 patients associated with 1,731 inpatient stays of a Clinic of Pediatric Oncology, Hematology, and Immunology in 2004 was analyzed by methods and means of G-DRG systems 2004, 2005, and 2006. DRGs and additional payments for drugs and procedures eligible for all and/or individual hospitals were calculated. G-DRG system 2005 resulted in overall reimbursement loss of 3.77 % compared to G-DRG 2004. G-DRG 2006 leads to slightly improved overall reimbursements compared to G-DRG 2005 by increasing DRG-based revenues. G-DRG 2006 effects 2.40 % reduction in overall reimbursement compared to G-DRG 2004. This loss includes ameliorating effects of additional payments for drugs and blood products already. Despite introduction of additional payments especially designed for children and teenagers in 2006, additional payment volume is decreased by 21.71 % from 2005 to 2006. G-DRG 2006 yields over-all reimbursement losses of 1.45 % in comparison to G-DRG 2004. Overall reimbursements include introduced additional payments for drugs and blood products. (Reimbursements resulting out of DRG payment alone drop by 14.73 % from 2004 to 2005, and increase by 3.26 % from 2005 to 2006 (2004 vs. 2006 11.95 %). Introduction of additional payments for drugs and blood products on a Germany-wide basis introduced in 2005 dampens DRG-based reimbursement losses. Despite introduction of dosage

  17. Slovensky plynarensky priemysel. Annual report 2004

    International Nuclear Information System (INIS)

    2005-01-01

    This Annual Report contains the review of the results of the joint stock company Slovensky plynarensky priemysel (SPP - Slovak Gas Industry) in relation to the year 2004. This report contains the following headings: (1) Statement by the Chairman of the Board of Directors; (2) Statement by the General Director; (3) ProgRes SPP - Profile of Changes; (4) Organisational Chart applicable since 1-st January 2005; (5) Board of Directors; (6) Supervisory Board; (7) Executive Management; (8) Business Activities; (9) Economic and Financial Highlights; (10) Capital Structure of Financial Sources Covering Assets; (11)Natural Gas Trade; (12) Natural Gas Distribution; (13) International Transmission of Natural Gas; (14) Human Resources; (15) Equity Holdings; (16) 2004 Summary Results; (17) Auditor's Report; (18) Environmental Protection; (19) Charity, Sponsoring, SPP Foundation; (20) Selected data from consolidated international financial statements for the year ended 31 December 2004 and Independent Auditor's Report

  18. A new socioeconomic status measure for vaccine research in children using individual housing data: a population-based case-control study

    Directory of Open Access Journals (Sweden)

    Rachel Hammer

    2016-09-01

    Full Text Available Abstract Background We recently developed HOUSES, an individual housing-based socioeconomic status (SES measurement for health disparities research. We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children. Methods The study utilized a previous population-based case-control study cohort assembled during the 20042005 pertussis outbreak. We collected data on pertussis vaccine status (up-to-date status at the time of the index date. Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES was formulated in continuous variable and categorized into quartiles. Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models. Results Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %, 363 (93 % were successfully geocoded to formulate HOUSES index. HOUSES was not associated with the risk of pertussis (p = 0.82. Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES, second, third, and fourth quartiles of HOUSES, respectively (p = 0.03. HOUSES as a continuous variable was associated with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04–1.27, p = 0.008. Conclusion While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES. HOUSES may be a useful tool for vaccine delivery research among children.

  19. The epidemiological and serological characteristics of measles in Dongguan, China, 2005–2014

    Science.gov (United States)

    Han, Ke; Chen, Shaoli; Tang, Cuifei; Wen, Jinjun; Li, Jingquan; Ni, Jindong; Zheng, Xueli

    2016-01-01

    ABSTRACT This study examined the epidemiological and serological characteristics of measles in Dongguan, China. From 2005 to 2014, a total of 8,224 measles cases were reported in Dongguan, 33.5% of which were aged 14 y. From 2005 to 2014, the proportion of the measles cases increased year by year from 24.3% to 47.9%. Of the cases aged ≥8 months (n = 6,768 cases), only 11.6% had been immunized with at least one dose of measles vaccine. Of the 2,213 cases who had never been immunized with measles vaccine, immigrants accounted for 82.4%. 52.4% of the measles cases were diagnosed with pneumonia, and 12 cases died from respiratory failure. Seroprevalence rate in women and their newborns was 86.0% and 82.5%, respectively. Measurement of serum measles antibody levels for infants aged less than 8 months indicated that seroprevalence rate dramatically declined from 97.3% at birth to 9.3% and 13.2% at 6- and 7- month old. The existence of a sufficient pool of unvaccinated people (especially immigrants) and decreased level of passively transferred measles antibodies in infants from vaccinated mothers contributed to the sustained transmission observed in Dongguan. In addition to high routine vaccination coverage, new strategies and innovations for measles vaccination are needed to eliminate measles. PMID:27003239

  20. Performance appraisal and advancement exercise 2005

    CERN Multimedia

    Human Resources Department

    2004-01-01

    The 2005 performance appraisal and advancement exercise will start in the usual way with annual interviews between staff and their supervisors. These interviews should be held in the period from 15 November 2004 to 15 February 2005 [see Administrative Circular No 26 (Rev. 5) Annex II, § 3. For this exercise, the paper MAPS form has been replaced by an electronic form in the EDH system, which is available via EDH (on the EDH desktop under Other Tasks / HR & Training) No changes have been made to the contents of the form. HR Department will shortly provide further information on this subject. Human Resources Department Tel. 73566

  1. Kalapüük ja -varud : [2000-2005 Eestis] / Vahur Võrel

    Index Scriptorium Estoniae

    Võrel, Vahur

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 47-49. Kalapüügi mahust enamiku ehk 75% moodustab Läänemere kalapüük. Diagramm: Kalapüügi ja kalakasvatuse struktuur 2003. a (% kogumahust). Tabelid: Püügikogused ja väärtused 2000-2002; Läänemere püügikvoodid

  2. Energy in Sweden 2004

    International Nuclear Information System (INIS)

    2004-11-01

    Energy in Sweden is published annually by the Swedish Energy Agency. Energy in Sweden 2004, together with its statistics supplement, Energy in Sweden: Facts and Figures 2004, is intended to provide decision-makers, journalists and the public with a single source of easily available information on conditions and developments in the energy sector. In recent years, Swedish energy and environmental policy has been increasingly concentrated on establishing or improving the long-term conditions for efficient energy markets and efficient use of energy. Restructuring of the Swedish electricity market, greater internationalisation and the effects of the energy system on the wider environment and on climate are important factors that influence the direction of energy policy and so also development of the energy markets. The line that was started by the 2002 Energy Policy Agreement, under the name of Working Together for a Reliable, Efficient and Environmentally Aware Energy Supply (Bill no. 2001/02:143), continues. The shift in taxation policy to encourage the move towards a sustainable energy system and reduced environmental impact continues, as exemplified by the introduction of the electricity certificate system on 1st May 2003. The negotiations that were started in 2003 with a view to progressive shut-down of nuclear power generation were broken off in October 2004 without having reached agreement with the nuclear power companies. As soon as the breakdown of the negotiations was announced, the Government, together with the Left Party and the Centre Party, stated that Barsebaeck 2 will be closed in 2005. Sweden's climate policy is based on the Climate Strategy Act (Bill no. 2001/02:55), which was adopted by Parliament in March 2002. It is expected that trading in emission rights, in accordance with the EU Emissions Trading Directive, will start in January 2005, with publication of national emission rights allocations on 30th September 2004. One of the more important tasks

  3. Dissolved inorganic carbon, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using CTD, bottle and other instruments from the DISCOVERY in the Indian Ocean from 2004-12-13 to 2005-01-21 (NODC Accession 0113538)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113538 includes chemical, discrete sample, physical and profile data collected from DISCOVERY in the Indian Ocean from 2004-12-13 to 2005-01-21 and...

  4. AREVA - first half 2005 sales figures

    International Nuclear Information System (INIS)

    2005-07-01

    First half 2005 sales for the AREVA group were up 1.1% to 5,396 million euros and 2.6% like-for-like, compared with 5,339 million euros for the same period in 2004.The change in foreign exchange rates had a negative impact of nearly (34) million euros between these two periods, which was much less than between the first half of 2003 and the same period in 2004. Sales are up 1.1% compared with the first half of 2004 (up 2.6% like-for-like); the euros (17.3) M impact of IFRS adoption is limited to the Front End division; Energy is up: Nuclear Power: up 4.4% (up 5.5% like-for-like), driven by the Front End and Reactors and Services divisions; T and D: down 3.9% (-2.1% like-for-like) due to the one time peak observed in early 2004; Connectors sales are stable (+0.3% like-for-like): Automotive performed well, while the communication market continued to be a difficult one

  5. Waste Isolation Pilot Plant Geotechnical Analysis Report for July 2004 - June 2005, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2006-04-03

    This Geotechnical Analysis Report (GAR) presents and interprets the geotechnical data from the underground excavations at the Waste Isolation Pilot Plant (WIPP). The data, which are obtained as part of a regular monitoring program, are used to characterize conditions, to compare actual performance to the design assumptions, and to evaluate and forecast the performance of the underground excavations. GARs have been available to the public since 1983. During the Site and Preliminary Design Validation (SPDV) Program, the architect/engineer for the project produced these reports quarterly to document the geomechanical performance during and immediately after early excavations of the underground facility. Since the completion of the construction phase of the project in 1987, the management and operating contractor for the facility has prepared these reports annually. This report describes the performance and condition of selected areas from July 1, 2004, to June 30, 2005. It is divided into nine chapters. Chapter 1 provides background information on WIPP, its mission, and the purpose and scope of the Geomechanical Monitoring Program. Chapter 2 describes the local and regional geology of the WIPP site. Chapters 3 and 4 describe the geomechanical instrumentation in the shafts and shaft stations, present the data collected by that instrumentation, and provide interpretation of these data. Chapters 5 and 6 present the results of geomechanical monitoring in the two main portions of the WIPP underground (the access drifts and the waste disposal area). Chapter 7 discusses the results of the Geoscience Program, which include fracture mapping and borehole observations. Chapter 8 summarizes the results of the geomechanical monitoring and compares the current excavation performance to the design requirements. Chapter 9 lists the references and bibliography.

  6. Waste Isolation Pilot Plant Geotechnical Analysis Report for July 2004 - June 2005, Volume 1

    International Nuclear Information System (INIS)

    2006-01-01

    This Geotechnical Analysis Report (GAR) presents and interprets the geotechnical data from the underground excavations at the Waste Isolation Pilot Plant (WIPP). The data, which are obtained as part of a regular monitoring program, are used to characterize conditions, to compare actual performance to the design assumptions, and to evaluate and forecast the performance of the underground excavations. GARs have been available to the public since 1983. During the Site and Preliminary Design Validation (SPDV) Program, the architect/engineer for the project produced these reports quarterly to document the geomechanical performance during and immediately after early excavations of the underground facility. Since the completion of the construction phase of the project in 1987, the management and operating contractor for the facility has prepared these reports annually. This report describes the performance and condition of selected areas from July 1, 2004, to June 30, 2005. It is divided into nine chapters. Chapter 1 provides background information on WIPP, its mission, and the purpose and scope of the Geomechanical Monitoring Program. Chapter 2 describes the local and regional geology of the WIPP site. Chapters 3 and 4 describe the geomechanical instrumentation in the shafts and shaft stations, present the data collected by that instrumentation, and provide interpretation of these data. Chapters 5 and 6 present the results of geomechanical monitoring in the two main portions of the WIPP underground (the access drifts and the waste disposal area). Chapter 7 discusses the results of the Geoscience Program, which include fracture mapping and borehole observations. Chapter 8 summarizes the results of the geomechanical monitoring and compares the current excavation performance to the design requirements. Chapter 9 lists the references and bibliography.

  7. Vaccine escape recombinants emerge after pneumococcal vaccination in the United States.

    Science.gov (United States)

    Brueggemann, Angela B; Pai, Rekha; Crook, Derrick W; Beall, Bernard

    2007-11-01

    The heptavalent pneumococcal conjugate vaccine (PCV7) was introduced in the United States (US) in 2000 and has significantly reduced invasive pneumococcal disease; however, the incidence of nonvaccine serotype invasive disease, particularly due to serotype 19A, has increased. The serotype 19A increase can be explained in part by expansion of a genotype that has been circulating in the US prior to vaccine implementation (and other countries since at least 1990), but also by the emergence of a novel "vaccine escape recombinant" pneumococcal strain. This strain has a genotype that previously was only associated with vaccine serotype 4, but now expresses a nonvaccine serotype 19A capsule. Based on prior evidence for capsular switching by recombination at the capsular locus, the genetic event that resulted in this novel serotype/genotype combination might be identifiable from the DNA sequence of individual pneumococcal strains. Therefore, the aim of this study was to characterise the putative recombinational event(s) at the capsular locus that resulted in the change from a vaccine to a nonvaccine capsular type. Sequencing the capsular locus flanking regions of 51 vaccine escape (progeny), recipient, and putative donor pneumococci revealed a 39 kb recombinational fragment, which included the capsular locus, flanking regions, and two adjacent penicillin-binding proteins, and thus resulted in a capsular switch and penicillin nonsusceptibility in a single genetic event. Since 2003, 37 such vaccine escape strains have been detected, some of which had evolved further. Furthermore, two new types of serotype 19A vaccine escape strains emerged in 2005. To our knowledge, this is the first time a single recombinational event has been documented in vivo that resulted in both a change of serotype and penicillin nonsusceptibility. Vaccine escape by genetic recombination at the capsular locus has the potential to reduce PCV7 effectiveness in the longer term.

  8. Radioactive waste management profiles. A compilation of data from the Net Enabled Waste Management Database (NEWMDB). No. 7, December 2005 (last updated 2005.12.15)

    International Nuclear Information System (INIS)

    2005-12-01

    This Profiles report is based on data collected using the NEWMDB from May to October 2005. The report was first published on line within the NEWMDB December 2005. Starting with NEWMDB version II (introduced January 2004) individual reports can be updated after a Profiles report is published. Please refer to the Profiles bookmark; the page that is accessed via this bookmark lists revisions to individual Profiles (if there are any)

  9. Clonal Distribution of Disease-Associated and Healthy Carrier Isolates of Neisseria meningitidis between 1983 and 2005 in Cuba ▿

    Science.gov (United States)

    Climent, Yanet; Yero, Daniel; Martinez, Isabel; Martín, Alejandro; Jolley, Keith A.; Sotolongo, Franklin; Maiden, Martin C. J.; Urwin, Rachel; Pajón, Rolando

    2010-01-01

    In response to epidemic levels of serogroup B meningococcal disease in Cuba during the 1980s, the VA-MENGOC-BC vaccine was developed and introduced into the National Infant Immunization Program in 1991. Since then the incidence of meningococcal disease in Cuba has returned to the low levels recorded before the epidemic. A total of 420 Neisseria meningitidis strains collected between 1983 and 2005 in Cuba were analyzed by multilocus sequence typing (MLST). The set of strains comprised 167 isolated from disease cases and 253 obtained from healthy carriers. By MLST analysis, 63 sequence types (STs) were identified, and 32 of these were reported to be a new ST. The Cuban isolates were associated with 12 clonal complexes; and the most common were ST-32 (246 isolates), ST-53 (86 isolates), and ST-41/44 (36 isolates). This study also showed that the application of VA-MENGOC-BC, the Cuban serogroup B and C vaccine, reduced the frequency and diversity of hypervirulent clonal complexes ST-32 (vaccine serogroup B type-strain) and ST-41/44 and also affected other lineages. Lineages ST-8 and ST-11 were no longer found during the postvaccination period. The vaccine also affected the genetic composition of the carrier-associated meningococcal isolates. The number of carrier isolates belonging to hypervirulent lineages decreased significantly after vaccination, and ST-53, a sequence type common in carriers, became the predominant ST. PMID:20042619

  10. PRESSÃO CAMBIAL E A DECISÃO DE INTERNACIONALIZAÇÃO:O CASO MARCOPOLO NO PERÍODO 2004/2005

    Directory of Open Access Journals (Sweden)

    LEONARDO NELMI TREVISAN

    2006-01-01

    Full Text Available Este trabalho examina procedimentos de internacionalização de empresa brasileira,a Marcopolo, ao longo dos anos de 2004 e 2005.O objetivo não é debater aspectosconjunturais (pressão cambial, essencialmente mas acompanhar decisões organizacionaistomadas a partir dela. Internacionalização de empresas obedece a dois quadros teóricos: oeconômico e o organizacional. Estudo com 76 empresas brasileiras que operam em mercadosinternacionais mostrou a presença da “interpretação gradualista da Escola de Uppsala”, mas“resultados superiores” ocorrem com desempenho global e menor dependência ao mercadodoméstico. A adesão ao “paradigma eclético de produção internacional” ocorreu na Marcopoloque procurou além fronteiras os meios de obter "margens mais adequadas" de lucros. Ainternacionalização da Marcopolo foi menos um processo de ação comportamental e mais umareação às condições de produção locais adversas.

  11. Antiradiation UV Vaccine: UV Radiation, Biological effects, lesions and medical management - immune-therapy and immune-protection.

    Science.gov (United States)

    Popov, Dmitri; Jones, Jeffrey; Maliev, Slava

    moderate and high doses of UV and ionizing radiation induce cell death by necrosis and generate systemic inflammatory response syndrome (SIRS), toxic multiple organ injury (TMOI), toxic multiple organ dysfunction syndromes (TMODS),and finally, toxic multiple organ failure (TMOF). [D.Popov et al.2012, Fliedner T.et al. 2005, T. Azizova et al. 2004] UV-B is a complete carcinogen that is absorbed by DNA and directly damages DNA. DNA damage induced by UV-B irradiation typically includes the formation of cyclobutane pyrimidine dimmers (CPD) and 6-4 photoproducts (6-4P)[IARC, Working Group Reports, M.Saraiya et al. 2004]. The pre-vaccinated animals seem to have a blunted injury response relative to the unvaccinated animals, presumably by reduction in the inflammatory response and secondary injury effects. The mechanism of action of the antiradiation vaccine, needs further evaluation. Conclusion: A UV antiradiation vaccine appears to demonstrate efficacy as a prophylactic agent for acute solar burns and toxicity. An antiradiation UV vaccine could be used in conjunction with adjunctive measures, e.g. antioxidants and UV barriers to reduce UV radiation toxicity. The authors of this experiments would like to propose further development work of the antiradiation UV vaccine to enhance the armamentarium for prophylaxis and prevention of the various forms skin cancer.

  12. Energy consumption 2005 with Danish industry

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    The energy consumption in the Danish industries decreased with 4% from 2003 to 2005. The consumption of liquid fuels and district heat decreased with 27% and 21%, respectively. The consumption of solid fuels increased with 13%. The aim of the statistics is to elucidate the industry's energy consumption and its composition. The statistics present the development in the industry from 1973 to 2005, in which period the composition of the energy consumption has changed significantly. Especially, consumption of liquid fuels has decreased and consumption of gas and electricity has increased. (ln)

  13. Racismo en el fútbol profesional español (1ª y 2ª división. Temporadas 2004-05 y 2005-06. (Racism in the Spanish professional football (1st and 2nd division. Seasons 2004-05 and 2005-06.

    Directory of Open Access Journals (Sweden)

    Rodrigo Pardo García

    2008-07-01

    Full Text Available ResumenEn la presente investigación se analizan los incidentes racistas ocurridos en los partidos de liga del fútbol profesional español en 1ª y 2ª división durante las temporadas 2004-05 y 2005-06. Para realizar dicho análisis se han empleado tres fuentes oficiales: 1. Actas de la Comisión Nacional contra la Violencia en los Espectáculos Deportivos, 2. Informes trimestrales realizados por la Oficina Nacional del Deporte perteneciente a la Dirección General de la Policía, y 3. Actas arbitrales. Los resultados muestran cómo el número total de incidentes racistas se mantuvo prácticamente constante en ambas temporadas aunque en 2ª división el número de incidentes se duplicó. En cuanto a la tipología de los incidentes recogidos, el 79% hace relación a conductas e insultos racistas mientras que el 21% restante se refiere a la exhibición de simbología de carácter racista. También se muestran datos de los clubes cuyos seguidores han ocasionado más incidentes racistas; cuántos de esos incidentes fueron protagonizados por grupos ultras; así como el número de personas implicadas y las propuestas de sanción realizadas por la Comisión Nacional contra la Violencia. Por último se reflejan los colegiados que recogieron en sus actas arbitrales incidentes racistas y/o xenófobos. Abstract This investigation analyzes the racist incidents occurred during spanish proffesional football games of the 1st and 2nd division in the seasons 2004-05 and 2005-06. To conduct such analysis it was used three official sources: 1. Minutes of the National Committee against Violence in Public Spectacles, 2. Quarterly reports elaborated by the Sport National Bureau belonging to the Police National Department, and 3. Referees’ minutes. Results show how the total number of racist incidents was practically the same in both seasons, however in the 2nd division the number of incidents was twice as compared to the 1st division. Regarding the typology of

  14. Lower Granite Dam Smolt Monitoring Program, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Mensik, Fred; Rapp, Shawn; Ross Doug (Washington Department of Fish and Wildlife, Olympia, WA)

    2005-11-01

    The 2004 fish collection season at Lower Granite Dam (LGR) was characterized by above average water temperatures, below average flows and spill, low levels of debris. The number of smolts collected for all species groups (with the exception of clipped and unclipped sockeye/kokanee) exceeded all previous collection numbers. With the continued release of unclipped supplementation chinook, steelhead and sockeye above LGR, we can not accurately distinguish wild chinook, wild steelhead and wild sockeye/kokanee from hatchery reared unclipped chinook and sockeye/kokanee in the sample. Wild steelhead can be identified from hatchery steelhead by the eroded dorsal and pectoral fins exhibited on unclipped hatchery steelhead. The numbers in the wild columns beginning in 1998 include wild and unclipped hatchery origin smolts. This season a total of 11,787,539 juvenile salmonids was collected at LGR. Of these, 11,253,837 were transported to release sites below Bonneville Dam, 11,164,132 by barge and 89,705 by truck. An additional 501,395 fish were bypassed to the river due to over-capacity of the raceways and for research purposes. According to the PTAGIS database, 177,009 PIT-tagged fish were detected at LGR in 2004. Of these, 105,894 (59.8%) were bypassed through the PIT-tag diversion system, 69,130 (39.1%) were diverted to the raceways to be transported, 1,640 (0.9%) were diverted to the sample tank, sampled and then transported, 345 (0.2%) were undetected at any of the bypass, raceway or sample exit monitors.

  15. Impact of uranium exploitation by Cogema-Areva subsidiaries in Niger. Assessment of analyses performed by the CRIIRAD laboratory in 2004 and at the beginning of 2005

    International Nuclear Information System (INIS)

    2005-01-01

    After a description of the uranium exploitation context (involved companies, production) in Arlit, Niger, by Cogema-Areva subsidiary companies, this report describes the context of controls performed by the CRIIRAD laboratory. Then, it reports and comments the contamination of underground so-called drinkable waters (contamination risks, Cogema statement, detection of a rather high concentration of alpha emitters, measurements performed in 2004 and 2005). The authors notice that water contamination is known by Cogema. Then, the report analyzes the issue of contaminated scrap metal dispersal, comments and criticizes the attitude of Cogema with respect to the associated risks. It comments the uranate transport accident which occurred in February 2004, the subsequent contamination, actions performed by Cogema, the associated health risks, and the statements made by Areva and Cogema. It also comments and analyzes the risks related to radioactive radon dusts inhalation around different sites and because of some technical practices, and Cogema statements about this issue. In conclusion, the authors outline the need of reinforced controls and of an epidemiological study, and outlines how Areva propagates wrong ideas

  16. NEW PREVENTION OPPORTUNITIES OF INFECTIOUS DISEASES. VACCINATION AGAINST ROTAVIRUS

    Directory of Open Access Journals (Sweden)

    T. A. Grechukha

    2013-01-01

    Full Text Available The article covers the problem of the burden of rotavirus disease. Rotavirus infection is the leading cause of mortality among children under 5 years of age and is a major problem for a public healthcare. The world is actively engaged in the prevention of rotavirus infection since 2005. There is a lot of data on the efficacy and safety of this vaccine. Different foreign investigations have shown the herd immunity of the vaccine. The authors present data about the effectiveness and safety of vaccines, established during clinical studies of the foreign scientists.

  17. Comparison between published clinical success of direct resin composite restorations in vital posterior teeth in 1995-2005 and 2006-2016 periods.

    Science.gov (United States)

    Alvanforoush, N; Palamara, J; Wong, R H; Burrow, M F

    2017-06-01

    Composites are increasing in popularity as restorative materials. This growing role indicates the necessity of studies on their clinical outcome. In this study, clinical studies published on the performance of posterior composite restorations were included except those of less than a 24-month assessment period. Results of non-vital, anterior or primary teeth and cervical single-surface restorations were also excluded. Records about composite type, number of final recall restorations, failure/survival rate, assessment period and failure reasons were analysed for each decade. Overall survival/failure rates for studies in 1995-2005 were 89.41%/10.59% and for 2006-2016 were 86.87%/13.13%, respectively. In 1995-2005, the reasons for failure were secondary caries (29.47%) and composite fracture (28.84%) with low tooth fracture (3.45%) compared with reasons of failure in 2006-2016, which were secondary caries (25.68%), composite fracture (39.07%), and tooth fracture (23.76%). An increase in incidence of composite fracture, tooth fracture and need for endodontic treatment as failure reasons was noted in the latter decade in addition to a decrease in secondary caries, postoperative sensitivity, unsatisfactory marginal adaptation and wear. The overall rates of failure showed little difference, but the causes showed a notable change. This is believed to be a reflection of increased use of composites for larger restorations and possibly changes of material characteristics. © 2016 Australian Dental Association.

  18. The influence of compositional and contextual factors on non-receipt of basic vaccines among children of 12-23-month old in India: a multilevel analysis.

    Science.gov (United States)

    Sissoko, Daouda; Trottier, Helen; Malvy, Denis; Johri, Mira

    2014-01-01

    Children unreached by vaccination are at higher risk of poor health outcomes and India accounts for nearly a quarter of unvaccinated children worldwide. The objective of this study was to investigate compositional and contextual determinants of non-receipt of childhood vaccines in India using multilevel modelling. We studied characteristics of unvaccinated children using the District Level Health and Facility Survey 3, a nationally representative probability sample containing 65 617 children aged 12-23 months from 34 Indian states and territories. We developed four-level Bayesian binomial regression models to examine the determinants of non-vaccination. The analysis considered two outcomes: completely unvaccinated (CUV) children who had not received any of the eight vaccine doses recommended by India's Universal Immunization Programme, and children who had not received any dose from routine immunisation services (no RI). The no RI category includes CUV children and those who received only polio doses administered via mass campaigns. Overall, 4.83% (95% CI: 4.62-5.06) of children were CUV while 12.01% (11.68-12.35) had received no RI. Individual compositional factors strongly associated with CUV were: non-receipt of tetanus immunisation for mothers during pregnancy (OR = 3.65 [95% CrI: 3.30-4.02]), poorest household wealth index (OR = 2.44 [1.81-3.22] no maternal schooling (OR = 2.43 [1.41-4.05]) and no paternal schooling (OR = 1.83 [1.30-2.48]). In rural settings, the influence of maternal illiteracy disappeared whereas the role of household wealth index was reinforced. Factors associated with no RI were similar to those for CUV, but effect sizes for individual compositional factors were generally larger. Low maternal education was the strongest risk factor associated with no RI in all models. All multilevel models found significant variability at community, district, and state levels net of compositional factors. Non-vaccination in India is

  19. The influence of compositional and contextual factors on non-receipt of basic vaccines among children of 12-23-month old in India: a multilevel analysis.

    Directory of Open Access Journals (Sweden)

    Daouda Sissoko

    Full Text Available Children unreached by vaccination are at higher risk of poor health outcomes and India accounts for nearly a quarter of unvaccinated children worldwide. The objective of this study was to investigate compositional and contextual determinants of non-receipt of childhood vaccines in India using multilevel modelling.We studied characteristics of unvaccinated children using the District Level Health and Facility Survey 3, a nationally representative probability sample containing 65 617 children aged 12-23 months from 34 Indian states and territories. We developed four-level Bayesian binomial regression models to examine the determinants of non-vaccination. The analysis considered two outcomes: completely unvaccinated (CUV children who had not received any of the eight vaccine doses recommended by India's Universal Immunization Programme, and children who had not received any dose from routine immunisation services (no RI. The no RI category includes CUV children and those who received only polio doses administered via mass campaigns. Overall, 4.83% (95% CI: 4.62-5.06 of children were CUV while 12.01% (11.68-12.35 had received no RI. Individual compositional factors strongly associated with CUV were: non-receipt of tetanus immunisation for mothers during pregnancy (OR = 3.65 [95% CrI: 3.30-4.02], poorest household wealth index (OR = 2.44 [1.81-3.22] no maternal schooling (OR = 2.43 [1.41-4.05] and no paternal schooling (OR = 1.83 [1.30-2.48]. In rural settings, the influence of maternal illiteracy disappeared whereas the role of household wealth index was reinforced. Factors associated with no RI were similar to those for CUV, but effect sizes for individual compositional factors were generally larger. Low maternal education was the strongest risk factor associated with no RI in all models. All multilevel models found significant variability at community, district, and state levels net of compositional factors.Non-vaccination in India

  20. A replicating modified vaccinia tiantan strain expressing an avian-derived influenza H5N1 hemagglutinin induce broadly neutralizing antibodies and cross-clade protective immunity in mice.

    Directory of Open Access Journals (Sweden)

    Haixia Xiao

    Full Text Available To combat the possibility of a zoonotic H5N1 pandemic in a timely fashion, it is necessary to develop a vaccine that would confer protection against homologous and heterologous human H5N1 influenza viruses. Using a replicating modified vaccinia virus Tian Tan strain (MVTT as a vaccine vector, we constructed MVTTHA-QH and MVTTHA-AH, which expresses the H5 gene of a goose-derived Qinghai strain A/Bar-headed Goose/Qinghai/1/2005 or human-derived Anhui Strain A/Anhui/1/2005. The immunogenicity profiles of both vaccine candidates were evaluated. Vaccination with MVTTHA-QH induced a significant level of neutralizing antibodies (Nabs against a homologous strain and a wide range of H5N1 pseudoviruses (clades 1, 2.1, 2.2, 2.3.2, and 2.3.4. Neutralization tests (NT and Haemagglutination inhibition (HI antibodies inhibit the live autologous virus as well as a homologous A/Xingjiang/1/2006 and a heterologous A/Vietnam/1194/2004, representing two human isolates from clade 2.2 and clade 1, respectively. Importantly, mice vaccinated with intranasal MVTTHA-QH were completely protected from challenge with lethal dosages of A/Bar-headed Goose/Qinghai/1/2005 and the A/Viet Nam/1194/2004, respectively, but not control mice that received a mock MVTTS vaccine. However, MVTTHA-AH induced much lower levels of NT against its autologous strain. Our results suggest that it is feasible to use the H5 gene from A/Bar-headed Goose/Qinghai/1/2005 to construct an effective vaccine, when using MVTT as a vector, to prevent infections against homologous and genetically divergent human H5N1 influenza viruses.

  1. Energy balances 2005

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    Denmark's energy consumption was 800 PJ in 2005 when corrected for the fuel consumption used for producing electricity for export. The consumption is 0,5 % higher than in 2004. Since 1975, the energy consumption has been on the same level with minor fluctuations which are mainly due to the climate. The energy balances is an account of production, import and export, and consumption of energy. The consumption is accounted as physical amounts as well as gross consumption. Also, accounts are presented of the costs of energy in basis prices and in market prices, including excises on energy, CO 2 , and SO 2 . (LN)

  2. Exploration and excavation of shipwrecks in Goa and adjoining waters 2004-2005

    Digital Repository Service at National Institute of Oceanography (India)

    Anon

    As a part of the Institutional Project, 'Application of geological and geophysical methods in marine archaeology and underwater explorations' (STS 0004), exploration and excavation of shipwrecks have been carried out from Nov 24-Dec 02, 2005 for 06...

  3. T–CELL VACCINE PREPARATION FOR MULTIPLE SCLEROSIS TREATMENT

    Directory of Open Access Journals (Sweden)

    I. P. Ivanova

    2005-01-01

    Full Text Available Abstract. A two–stage technology of preparation of T–cell vaccine designated for multiple sclerosis treatment is described. At the first stage myelin–specific lymphocytes undergoe antigen–dependent cultural selection, whereas at the second stage they are grown by means of non–specific stimulation. The vaccine prepared in this way was found to induce specific anti–idiotypic immune response, directed against myelin–reactive T–lymphocytes. The results of 1–year follow–up of 18 vaccinated patients with a cerebral–spinal type of multiple sclerosis indicated the absence of side effects of T–cell vaccination, and suggest the possibility of effective application of this treatment within early stages of disease. (Med. Immunol., 2005, vol.7, № 1, pp 27532

  4. Macromolecular systems for vaccine delivery.

    Science.gov (United States)

    MuŽíková, G; Laga, R

    2016-10-20

    Vaccines have helped considerably in eliminating some life-threatening infectious diseases in past two hundred years. Recently, human medicine has focused on vaccination against some of the world's most common infectious diseases (AIDS, malaria, tuberculosis, etc.), and vaccination is also gaining popularity in the treatment of cancer or autoimmune diseases. The major limitation of current vaccines lies in their poor ability to generate a sufficient level of protective antibodies and T cell responses against diseases such as HIV, malaria, tuberculosis and cancers. Among the promising vaccination systems that could improve the potency of weakly immunogenic vaccines belong macromolecular carriers (water soluble polymers, polymer particels, micelles, gels etc.) conjugated with antigens and immunistumulatory molecules. The size, architecture, and the composition of the high molecular-weight carrier can significantly improve the vaccine efficiency. This review includes the most recently developed (bio)polymer-based vaccines reported in the literature.

  5. 75 FR 57063 - Distribution of the 2004 and 2005 Cable Royalty Funds

    Science.gov (United States)

    2010-09-17

    ..., Huron Consulting Group, Tr. at 36-37; John F. Wilson, Senior Vice President & Chief TV Programming... 1529; Jonda K. Martin, id. at 1529-30; Dr. Martin R. Frankel, Professor of Statistics and Computer...\\ regarding certain programming on Station WGN-TV (Chicago, Illinois) during the years 1998-99 and 2004-05...

  6. Risk of Guillain-Barré syndrome after meningococcal conjugate vaccination.

    Science.gov (United States)

    Velentgas, Priscilla; Amato, Anthony A; Bohn, Rhonda L; Chan, K Arnold; Cochrane, Thomas; Funch, Donnie P; Dashevsky, Inna; Duddy, April L; Gladowski, Patricia; Greenberg, Steven A; Kramer, Judith M; McMahill-Walraven, Cheryl; Nakasato, Cynthia; Spettell, Claire M; Syat, Beth L; Wahl, Peter M; Walker, Alexander M; Zhang, Fang; Brown, Jeffrey S; Platt, Richard

    2012-12-01

    A new meningococcal conjugate vaccine (MCV4) was introduced in 2005. Shortly after, case reports of Guillain-Barré syndrome (GBS), a serious demyelinating disease, began to be reported to the Vaccine Adverse Event Reporting System. In 2006, the Centers for Disease Control and Prevention and the Food and Drug Administration requested the evaluation of GBS risk after MCV4 vaccination. We conducted a study to assess the risk of GBS after MCV4 vaccination using health plan administrative and claims data together with the review of primary medical records of potential cases. Retrospective cohort study among 12.6 million 11- to 21-year-old members of five US health plans with a total membership of 50 million. Automated enrollment and medical claims data from March 2005 through August 2008 were used to identify the population, the vaccinations administered, and the medical services associated with possible GBS. Medical records were reviewed and adjudicated by a neurologist panel to confirm cases of GBS. The study used distributed data analysis methods that minimized sharing of protected health information. We confirmed 99 GBS cases during 18,322,800 person-years (5.4/1,000,000 person-years). More than 1.4 million MCV4 vaccinations were observed. No confirmed cases of GBS occurred within 6 weeks after vaccination. The upper 95% CI for the attributable risk of GBS associated with MCV4 is estimated as 1.5 cases per 1,000,000 doses. Among members of five US health plans, MCV4 vaccination was not associated with increased GBS risk. Copyright © 2012 John Wiley & Sons, Ltd.

  7. 2005. aasta arhitektuurivõistlused

    Index Scriptorium Estoniae

    2005-01-01

    Tulemused: Viljandi Metsakalmistu kabel: I - Andres Lember (Male Arhitektid); Tartu Vabaduse sild: I - Stanislav Shulman, Oleg Samohhin (Peterburi, Transmost); Tartu Mõisavahe kvartali hoonestuskava: I .- Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos); Seewaldi ala planeerimine: I - Jüri Martson, Rasmus Reinolt, Ivo-Martin Veelma (Lokomotiiv); Rotermanni kvartali arhitektuurivõistlus: I - Kosmos; aasta betoonehitis 2004: Ülemiste hotell Tallinnas, Martin Aunin; Lasnamäe Jumalaema kirik: I - Oleg Zhemtshugov (AB Z-Projekt), Nikolai Djatko, Jevgeni Kolomenkin; Pärnu vanalinna ja rannapiirkonna tänavakaubanduse inventari ja jäätmejaamade kujundus: I - Peeter Varrak; Kihnu sadamaala planeerimise ja hoonestamise ideevõistlus: I - Siiri Vallner, Kaire Nõmm, Helina Lass, Anna-Liisa Unt (Kavakava); Narva kolledzhi uus hoone: I - Katrin Koov, S. Vallner (Kavakava) ja Indrek Peil (Head Arhitektid); Randvere algkooli hoone: II - Inga Raukas (Arhitektuuriagentuur); Tartu Toomemäe valgustuse ja arhitektuursete väikevormide ideevõistlus: II - K. Koov ja Heidi Urb (Kabvakava) ning Maarja Kask, Ralf Lõoke, Karli Luik (Salto); Metsakalmistu arhitektide kalmeala: I - M. Kask, R. Lõoke; Skoone bastioni ideevõistlus: I - M. Kask, R. Lõoke, K. Luik (Salto); Mahtra talurahvamuuseum: I -Tomomi Hayashi, Hanno Grossschmidt; parim eramu 2004-2005: metallmaja Tabasalus, Muru & Pere; Tallinna loomaaia läänevärav: I - I. Raukas, Monika Löve, Oliver Soomets; parim puitehitis 2005: Naba lasteaed Pirital, arhitektid Vahur Sova, Lauri Saar, sisearhitekt Mari Tosmin; Pae karjääri revitaliseerimine: III - Veronika Valk, Kerli Raamsalu

  8. Water Use in Florida, 2005 and Trends 1950-2005

    Science.gov (United States)

    Marella, Richard L.

    2008-01-01

    Water is among Florida's most valued resources. The State has more than 1,700 streams and rivers, 7,800 freshwater lakes, 700 springs, 11 million acres of wetlands, and underlying aquifers yielding quantities of freshwater necessary for both human and environmental needs (Fernald and Purdum, 1998). Although renewable, these water resources are finite, and continued growth in population, tourism, and agriculture will place increased demands on these water supplies. The permanent population of Florida in 2005 totaled 17.9 million, ranking fourth in the Nation (University of Florida, 2006); nearly 86 million tourists visited the State (Orlando Business Journal, 2006). In 2005, Florida harvested two-thirds of the total citrus production in the United States and ranked fifth in the Nation net farm income (Florida Department of Agriculture and Consumer Services, 2006). Freshwater is vital for sustaining Florida's population, economy, and agricultural production. Accurate estimates reflecting water use and trends in Florida are compiled in 5-year intervals by the U.S. Geological Survey (USGS) in cooperation with the Florida Department of Environmental Protection (FDEP) and the Northwest Florida, St. Johns River, South Florida, Southwest Florida, and Suwannee River Water Management Districts (Marella, 2004). This coordinated effort provides the necessary data and information for planning future water needs and resource management. The purpose of this fact sheet is to present the highlights of water use in Florida for 2005 along with some significant trends in withdrawals since 1950.

  9. Lack of nonspecific protection against all-cause nonrotavirus gastroenteritis by vaccination with orally administered rotavirus vaccine.

    Science.gov (United States)

    Grant, Lindsay; Watt, James; Moulton, Lawrence; Weatherholtz, Robert; Reid, Raymond; Santosham, Mathuram; O'Brien, Katherine

    2013-06-01

    Acute gastroenteritis (AGE) is recognized as a global, common threat to child survival, especially in developing countries. Rotavirus, in particular, has been implicated as a leading cause of severe AGE; however, there are numerous other pathogens that also cause AGE. Several studies have demonstrated that oral vaccination against rotavirus has generated the unanticipated benefit of protecting against AGE caused by nonrotavirus pathogens. Safety and efficacy of the pentavalent bovine-human reassortant rotavirus vaccine were studied in multiple populations, including children of the Navajo and White Mountain Apache tribes in the southwestern United States. Stool specimens were collected from children with AGE and tested for rotavirus using an enzyme immunoassay. Analyses were conducted to detect the presence or absence of a vaccine effect on incidence, severity, and duration of AGE in which rotavirus was not detected. The majority of AGE (N = 558: 472 nonrotavirus vs 86 rotavirus) occurred between August 2002 and March 2004 among children ranging from ages 4 to 23 months. The incidence of nonrotavirus AGE was similar by vaccine groups with an incidence rate ratio of 1.07 (incidence rate ratio = vaccinated/unvaccinated, 95% confidence interval 0.89-1.29). The hazards of first, second, third, or any AGE in which rotavirus was not detected differed little by vaccination status (P > 0.05). Duration of symptoms and severity of nonrotavirus AGE were similar by vaccine group. There was no vaccine effect on frequency or severity of nonrotavirus AGE.

  10. Emergency measles control activities--Darfur, Sudan, 2004.

    Science.gov (United States)

    2004-10-01

    The Darfur region of Sudan, composed of three states with a population of approximately six million, has experienced civil conflict during the previous year, resulting in the internal displacement of approximately one million residents and an exodus of an estimated 170,000 persons to neighboring Chad. The conflict has left a vulnerable population with limited access to food, health care, and other basic necessities. In addition, measles vaccination coverage has been adversely affected; in 2003, coverage was reported to be 46%, 57%, and 77% in North, West, and South Darfur, respectively. This report describes measles-control activities in Darfur region conducted by the Federal Ministry of Health (FMOH) in Sudan in collaboration with the United Nations and nongovernmental organizations (NGOs) during March-August 2004. Ongoing measles transmission in camps for internally displaced persons (IDPs) and neighboring communities in Darfur led to a regionwide measles vaccination campaign targeting all children aged 9 months-15 years, resulting in a reduction in reported measles cases. Once security is improved, ongoing efforts to increase measles vaccine coverage will be required to eliminate persistent susceptibility to measles in the Darfur population.

  11. Nevada Test Site-Directed Research, Development, and Demonstration. FY2005 report

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Will [comp.

    2006-09-01

    The Nevada Test Site-Directed Research, Development, and Demonstration (SDRD) program completed a very successful year of research and development activities in FY 2005. Fifty new projects were selected for funding this year, and five FY 2004 projects were brought to conclusion. The total funds expended by the SDRD program were $5.4 million, for an average per project cost of just under $100,000. Two external audits of SDRD accounting practices were conducted in FY 2005. Both audits found the program's accounting practices consistent with the requirements of DOE Order 413.2A, and one included the observation that the NTS contractor ''did an exceptional job in planning and executing year-start activities.'' Highlights for the year included: the filing of 18 invention disclosures for intellectual property generated by FY 2005 projects; programmatic adoption of 17 FY 2004 SDRD-developed technologies; participation in the tri-lab Laboratory Directed Research and Development (LDRD) and SDRD program review that was broadly attended by NTS, NNSA, LDRD, and U.S. Department of Homeland Security representatives; peer reviews of all FY 2005 projects; and the successful completion of 55 R&D projects, as presented in this report.

  12. Waste statistics 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-07

    The 2004 reporting to the ISAG comprises 394 plants owned by 256 enterprises. In 2003, reports covered 403 plants owned by 273 enterprises. Waste generation in 2004 is compared to targets for 2008 in the government's Waste Strategy 2005-2008. The following summarises waste generation in 2004: 1) In 2004, total reported waste arisings amounted to 13,359,000 tonnes, which is 745,000 tonnes, or 6 per cent, more than in 2003. 2) If amounts of residues from coal-fired power plants are excluded from statistics, waste arisings in 2004 were 12,179,000 tonnes, which is a 9 per cent increase from 2003. 3) If amounts of residues from coal-fired power plants and waste from the building and construction sector are excluded from statistics, total waste generation in 2004 amounted to 7,684,000 tonnes, which is 328,000 tonnes, or 4 per cent, more than in 2002. In other words, there has been an increase in total waste arisings, if residues and waste from building and construction are excluded. Waste from the building and construction sector is more sensitive to economic change than most other waste. 4) The total rate of recycling was 65 per cent. The 2008 target for recycling is 65 per cent. The rate of recycling in 2003 was also 65 per cent. 5) The total amount of waste led to incineration amounted to 26 per cent, plus an additional 1 per cent left in temporary storage to be incinerated at a later time. The 2008 target for incineration is 26 per cent. These are the same percentage figures as applied to incineration and storage in 2003. 6) The total amount of waste led to landfills amounted to 8 per cent, which is one percentage point better than the overall landfill target of a maximum of 9 per cent landfilling in 2008. Also in 2003, 8 per cent of the waste was landfilled. 7) The targets for treatment of waste from individual sectors are still not being met: too little waste from households and the service sector is being recycled, and too much waste from industry is being

  13. The 2005 energy year in Finland: Electricity consumption down

    International Nuclear Information System (INIS)

    2006-01-01

    Electricity consumption declined by 2.5% in 2005, largely as a result of a six-week labour dispute in the paper indusry and mild weather conditions, according to a report on energy industry develop rents in 2005 published by Finnish Energy Industries. Over the longer term, energy consumption is forecast to grow by close to 2% a year. Water levels in waterways and water systems across the Nordic countries returned to normal in 2005 after a long period of reduced resources, stabilising hydropower output generally Following high levels of electricity exports westwards in 2004, electricity imports from the West reached almost record levels in Finland in 2005. Together with imports from Russia, Finland imported more electricity last year than ever before - and a full fifth of Finland's energy needs were covered by net electricity imports in 2005. Two thirds of imports came from Russia, with imports reaching almost the maximum capacity of the countries' interconnectors

  14. Malaysia and the United States 2004-2005: The Best of Times

    Science.gov (United States)

    2005-02-01

    personal style stands in sharp contrast to that of his acerbic predecessor, Dr. Mahathir bin Mohamad. On a visit to the White House in July 2004, Prime...not as outspoken or as critical as his predecessor Datuk Seri Dr. Mahathir bin Mohamad, but also a reflection of the importance Kuala Lumpur places on...cancelled some of the hugely expensive mega projects that were the hallmark of the Mahathir era. One of the most important aspects of the election was the

  15. Results of monitoring at Olkiluoto in 2005. Foreign materials

    International Nuclear Information System (INIS)

    Vuorio, M.

    2006-08-01

    In this report the use of foreign materials in ONKALO is reviewed. The material handbook includes materials allowed for use in ONKALO as well as those that are forbidden. This monitoring report covers the foreign materials and the amounts used in ONKALO during 2005. During that time the access tunnel was excavated from chainage 155 m to chainage 990 m (a total 38231 m 3 of excavated rock). This report also summarises the total amount of materials used in ONKALO since the start of construction (2004-2005). (orig.)

  16. Discussions of Adolescent Sexuality in News Media Coverage of the HPV Vaccine

    Science.gov (United States)

    Casciotti, Dana M.; Smith, Katherine C.; Tsui, Amy

    2017-01-01

    Given the sexually transmitted nature of human papillomavirus (HPV), some worry the HPV vaccine will create a false sense of security and promote adolescent sexual activity. Media coverage of vaccines can influence social norms, parental attitudes, and vaccine acceptance; in this paper we examine U.S. news media messages related to sexuality and HPV vaccination. Drawing on a structured analysis of 447 articles published during 2005-2009, we qualitatively analyzed a purposive sample of 49 articles discussing adolescent health behaviors related to HPV vaccination. Commonly, articles discussed vaccination in the context of abstinence-only versus comprehensive sexual health education; cited research findings to support vaccination or sex education; argued against connecting vaccination to promiscuous behavior; but included fear-inducing messages. Media messages concerning health behaviors related to HPV vaccination tended to support government and parental involvement in sex education, and dismiss concerns linking vaccination to sexual activity, while also presenting the vaccine as lifesaving. PMID:24439619

  17. [Comparative analysis on the complete genome sequence of mumps epidemic strain and mumps vaccine strain S79 isolated in Zhejiang province, China between year 2005 and 2010].

    Science.gov (United States)

    Zhang, Dong-Yan; Feng, Yan; Zhong, Shu-Ling; Lu, Yi-Yu; Zhuang, Fang-Cheng; Xu, Chang-Ping

    2012-03-01

    To compare the differences in the complete genome sequence between mumps epidemic strain and mumps vaccine strain S79 isolated in Zhejiang province. A total of 4 mumps epidemic strains, which were separated from Zhejiang province during 2005 to 2010, named as ZJ05-1, ZJ06-3, ZJ08-1 and ZJ10-1 were selected in the study. The complete genome sequences were amplified using RT-PCR. The genetic differences between vaccine strain S79 and other genotype strains were compared; while the genetic-distance was calculated and the evolution was analyzed. The biggest difference between the 4 epidemic strains and the vaccine strain S79 was found on the membrane associated protein gene; whose average nucleotide differential number was 42.5 +/- 3.0 and the average variant ratio was 13.6%; while the mean amino acid differential number was 12.8 +/- 1.5 and the average variant ratio was 22.4%. The smallest difference among the 4 epidemic strains and the vaccine strain was found in stromatin genes, whose average nucleotide differential number was 73.8 +/- 2.5 and the average variant ratio was 5.9%; while the mean amino acid differential number was 3.0 +/- 0.8 and the average variant ratio was 0.8%. The dn/ds value of the stromatin genes of the 4 epidemic strains reached the highest, as 0.6526; but without any positive pressure (dn/ds 0.05). There were mutations happened on the known antigen epitope, as 8th amino acid of membrane associated protein genes and on the 336th and 356th amino acid of hemagglutinin/neuraminidase proteins. Compared with the vaccine strain, the glycosylation sites of ZJ05-1, ZJ06-3, ZJ08-1 and ZJ10-1 increased 1, 1, 2 and 2 respectively. The complete amino acid sequence of all strains showed that there were 17 characteristic sites found on the genotype-F mumps strain. Within the complete genome, the genetic-distance between epidemic strains and vaccine strains in Zhejiang province (0.071) was significantly larger than the genetic-distance between strains in

  18. Pay Inequities for Recently Hired Faculty, 1988-2004

    Science.gov (United States)

    Porter, Stephen R.; Toutkoushian, Robert K.; Moore, John V., III

    2008-01-01

    The national media and academic journals have reported a sizable wage gap between men and women in academe--a gap that has persisted over time. Data from the National Center for Education Statistics for 2004-2005 show that the average salary for all male faculty ($69,337) exceeded the average salary for female faculty ($56,926) by almost 22%.…

  19. Geotechnical Analysis Report for July 2004 - June 2005, Volume 2, Supporting Data

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2006-03-20

    This report is a compilation of geotechnical data presented as plots for each active instrument installed in the underground at the Waste Isolation Pilot Plant (WIPP) through June 30, 2005. A summary of the geotechnical analyses that were performed using the enclosed data is provided in Volume 1 of the Geotechnical Analysis Report (GAR).

  20. Geotechnical Analysis Report for July 2004 - June 2005, Volume 2, Supporting Data

    International Nuclear Information System (INIS)

    2006-01-01

    This report is a compilation of geotechnical data presented as plots for each active instrument installed in the underground at the Waste Isolation Pilot Plant (WIPP) through June 30, 2005. A summary of the geotechnical analyses that were performed using the enclosed data is provided in Volume 1 of the Geotechnical Analysis Report (GAR).

  1. Worldwide Emerging Environmental Issues Affecting the U.S. Military. April 2004 - April 2005

    Science.gov (United States)

    2005-04-01

    Reactors ( RERTR ) held in Vienna, November 8-11. [November 2004. Military Implications and Sources] Revival of Nuclear Power in Asia Poses Security...Military Implications: If not already done, the military should contact the RERTR Program managed by the Argonne National Laboratory of the U.S

  2. Niveles de plomo sanguíneo en recién nacidos de La Oroya, 2004-2005

    Directory of Open Access Journals (Sweden)

    Godofredo Pebe

    2008-10-01

    Full Text Available Objetivo. Determinar los niveles de plomo en sangre de los recién nacidos (RN de menos de 12 horas de vida, en la ciudad de La Oroya. Material y métodos. Estudio descriptivo, transversal y prospectivo realizado entre junio de 2004 a junio de 2005 de una muestra de recién nacidos (RN de La Oroya, se usó un cuestionario para la madre gestante y se determinó los niveles de plomo en sangre venosa (2 mL utilizando la espectrofotometría por absorción atómica con llama de aire de acetileno. Los valores se expresan en microgramos de plomo por decilitro de sangre (μg/dL. Resultados. Se evaluσ 93 RN; el nivel promedio de plomo en sangre fue de 8,84 ± 0,57 μg/dL. El 75,3% (70/ RN tuvo niveles de plomo en sangre entre 6 a 10 μg/dL, y 24,7% (23 RN tuvo mαs de 10 μg/dL. Los RN de madres que viven en La Oroya Nueva tienen menos niveles de plomo que los que viven en La Oroya Antigua (p=0,002. Conclusiones. Los RN de la ciudad de La Oroya presentan elevados niveles de plomo en sangre, por lo que se requiere iniciar programas de prevención en las madres gestantes para evitar futuros daños a la salud de los recién nacidos.

  3. EpiReview: Typhoid fever, NSW, 2005-2011.

    Science.gov (United States)

    Gunaratnam, Praveena; Tobin, Sean; Seale, Holly; Musto, Jennie

    2013-11-01

    To examine trends in the incidence of typhoid fever in NSW to inform the development of prevention strategies. Typhoid fever case notification data for the period 2005-2011 were extracted from the NSW Notifiable Conditions Information Management System. Population incidence rates were calculated and analysed by demographic variables. There were 250 case notifications of typhoid fever in NSW from 2005 to 2011, of which 240 are likely to have been acquired overseas. Case notifications remained relatively stable over the review period with the highest rates in Western Sydney Local Health District (10.9 per 100,000 population). Two-thirds (66.4%) of all case notifications are likely to have been acquired in South Asia, and about half of overseas-acquired case notifications were most likely to have been associated with travel to visit friends and relatives. Hospitalisation was required for 79.6% of cases where hospitalisation status was known. Prior typhoid vaccination was reported in 7% of cases in 2010 and 2011 where vaccination status was known. While typhoid fever rates remain low in NSW, case notifications of this preventable infection continue to be reported, particularly in travellers visiting friends and relatives in South Asia. Further research to better understand barriers to the use of preventive measures may be useful in targeting typhoid fever prevention messages in high-risk groups, particularly South Asian communities in NSW.

  4. WIPP 2004 Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2005-09-30

    The mission of Waste Isolation Pilot Plant (WIPP) is to safely and permanently dispose of transuranic (TRU) radioactive waste generated by the production of nuclear weapons and other activities related to the national defense of the United States (U.S.). In 2004, 8,839 cubic meters (m3) of TRU waste were emplaced at WIPP. From the first receipt of waste in March 1999 through the end of 2004, 25,809 m3 of TRU waste had been emplaced at WIPP. The U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) and Washington TRU Solutions LLC (WTS) are dedicated to maintaining high quality management of WIPP environmental resources. DOE Order 450.1, Environmental Protection Program; DOE Order 231.1A, Environment, Safety, and Health Reporting; and DOE Order 5400.5, Radiation Protection of the Public and Environment, require that the environment at and near DOE facilities be monitored to ensure the safety and health of the public and the environment. This Waste Isolation Pilot Plant 2004 Site Environmental Report (SER) summarizes environmental data from 2004 that characterize environmental management performance and demonstrate compliance with applicable federal and state regulations. This report was prepared in accordance with DOE Order 231.1A, and Guidance for the Preparation of DOE Annual Site Environmental Reports (ASERs) for Calendar Year 2004 (DOE, 2005). The order and the guidance require that DOE facilities submit an annual SER to the DOE Headquarters Office of the Assistant Secretary for Environment, Safety, and Health. The WIPP Hazardous Waste Facility Permit (HWFP) further requires that the SER be provided to the New Mexico Environment Department (NMED).

  5. WIPP 2004 Site Environmental Report

    International Nuclear Information System (INIS)

    2005-01-01

    The mission of Waste Isolation Pilot Plant (WIPP) is to safely and permanently dispose of transuranic (TRU) radioactive waste generated by the production of nuclear weapons and other activities related to the national defense of the United States (U.S.). In 2004, 8,839 cubic meters (m3) of TRU waste were emplaced at WIPP. From the first receipt of waste in March 1999 through the end of 2004, 25,809 m3 of TRU waste had been emplaced at WIPP. The U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) and Washington TRU Solutions LLC (WTS) are dedicated to maintaining high quality management of WIPP environmental resources. DOE Order 450.1, Environmental Protection Program; DOE Order 231.1A, Environment, Safety, and Health Reporting; and DOE Order 5400.5, Radiation Protection of the Public and Environment, require that the environment at and near DOE facilities be monitored to ensure the safety and health of the public and the environment. This Waste Isolation Pilot Plant 2004 Site Environmental Report (SER) summarizes environmental data from 2004 that characterize environmental management performance and demonstrate compliance with applicable federal and state regulations. This report was prepared in accordance with DOE Order 231.1A, and Guidance for the Preparation of DOE Annual Site Environmental Reports (ASERs) for Calendar Year 2004 (DOE, 2005). The order and the guidance require that DOE facilities submit an annual SER to the DOE Headquarters Office of the Assistant Secretary for Environment, Safety, and Health. The WIPP Hazardous Waste Facility Permit (HWFP) further requires that the SER be provided to the New Mexico Environment Department (NMED).

  6. The 2005 energy situation in France; Bilan energetique de l'annee 2005 en France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-15

    After a year 2004 of economic revival, 2005 shows a crisis of the energy prices and a slow economic activity. The year is characterized by again a petroleum consumption decrease, a poor hydro electric power which generates an increase of the fossil fuels consumption and finally a little increase of the primary energy consumption and CO{sub 2} emissions. It provides more details on the economic and energy context, on the energy consumption and production and on the carbon dioxide emissions from the energy. (A.L.B.)

  7. [Meningococcal C conjugate vaccine: Impact of a vaccination program and long-term effectiveness in Navarra, Spain, 2000-2014].

    Science.gov (United States)

    Morales, Desirée; García-Cenoz, Manuel; Moreno, Laura; Bernaola, Enrique; Barricarte, Aurelio; Castilla, Jesús

    2016-12-01

    Since 2000, when the meningococcal serogroupC conjugate vaccine (MenCC) was introduced in the childhood immunization schedule in Spain, several changes in the schedule and catch-up campaigns have been performed. We aim to estimate the impact and effectiveness of this vaccine in Navarra up to 2014. The impact of the vaccination program was analysed by comparing incidence, mortality and lethality rates of disease before (1995-1999) and after (2004-2014) the introduction of the MenCC. Vaccine effectiveness was estimated using the screening method (Farrington) and the indirect cohort method (Broome). Data on cases were obtained from the active surveillance of meningococcal disease. During 1995-1999 the mean annual incidence of meningococcalC disease was 1.32 per 100,000, and 7.18 per 100,000 in children younger than 15years. The fall of meningococcalC disease incidence was significant in cohorts targeted for vaccination from the beginning and progressive in the general population. No cases were reported between 2011 and 2014. The estimated vaccine effectiveness was 96% by the screening method, and 99% by the indirect cohort method. The MenCC vaccination program has been successful in decreasing the incidence rate of serogroupC meningococcal disease in Navarra, and schedule changes have maintained high vaccine effectiveness throughout the study period. Copyright © 2015 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  8. [Eradication of poliomyelitis and emergence of pathogenic vaccine-derived polioviruses: from Madagascar to Cameroon].

    Science.gov (United States)

    Delpeyroux, Francis; Colbère-Garapin, Florence; Razafindratsimandresy, Richter; Sadeuh-Mba, Serge; Joffret, Marie-Line; Rousset, Dominique; Blondel, Bruno

    2013-11-01

    The oral poliovaccine, a live vaccine made of attenuated poliovirus strains, is the main tool of the vaccination campaigns organised for eradicating poliomyelitis. these campaigns had led to the decline and, thereafter, to the disappearance of wild poliovirus strains of the three serotypes (1-3) in most parts of the world. However, when the poliovaccine coverage becomes too low, vaccine polioviruses can circulate in insufficiently immunized populations and become then pathogenic by mutations and genetic recombination with other enteroviruses of the same species, in particular some coxsackievirus A. These mutated and recombinant vaccine strains have been implicated in several epidemics of paralytic poliomyelitis. Two polio outbreaks associated with these pathogenic circulating vaccine-derived poliovirus (cVDPV) occurred in 2001-2002 and 2005 in the South of Madagascar where vaccine coverage was low. These cVDPV, of serotype 2 or 3, were isolated from paralyzed children and some of their healthy contacts. Other cVDPV were isolated in the same region from healthy children in 2011, indicating that these viruses were circulating again. Vaccination campaigns could stop the outbreaks in 2002 and 2005, and most probably prevent another one in 2011. Therefore, the genetic plasticity of poliovaccine strains that threatens the benefit of vaccination campaigns is the target of an accurate surveillance and an important theme of studies in the virology laboratories of the Institut Pasteur international network. © 2013 médecine/sciences – Inserm.

  9. No intention to comply with influenza and pneumococcal vaccination : behavioural determinants among smokers and non-smokers

    NARCIS (Netherlands)

    Looijmans-van den Akker, I; van den Heuvel, P.M.; Verheij, Th J M; van Delden, J J M; van Essen, G A; Hak, E

    OBJECTIVE: Smoking increases the risk for influenza and pneumococcal disease, but vaccination uptake is lower among smokers than non-smokers. We therefore aimed to determine reasons for not complying with vaccination among smokers and non-smokers. METHOD: In 2005 a self-administered questionnaire

  10. First quarter 2005 sales data; Chiffre d'affaires du 1. trimestre 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-04-15

    This press release brings information on the AREVA group sales data. First quarter 2005 sales for the group were 2,496 millions of euros, up 3,6% year-on-year from 2,41 millions. The change in foreign exchange rates between the two periods show a negative impact of 22 millions euros, which is much lower than in the first quarter of 2004. It analyzes also in more details the situation of the front end, the reactors and service division, the back end division, the transmission and distribution division and the connectors division. (A.L.B.)

  11. Discussions of adolescent sexuality in news media coverage of the HPV vaccine.

    Science.gov (United States)

    Casciotti, Dana M; Smith, Katherine C; Tsui, Amy; Klassen, Ann C

    2014-02-01

    Given the sexually transmitted nature of human papillomavirus (HPV), some worry the HPV vaccine will create a false sense of security and promote adolescent sexual activity. Media coverage of vaccines can influence social norms, parental attitudes, and vaccine acceptance; in this paper we examine U.S. news media messages related to sexuality and HPV vaccination. Drawing on a structured analysis of 447 articles published during 2005-2009, we qualitatively analyzed a purposive sample of 49 articles discussing adolescent health behaviors related to HPV vaccination. Commonly, articles discussed vaccination in the context of abstinence-only versus comprehensive sexual health education; cited research findings to support vaccination or sex education; argued against connecting vaccination to promiscuous behavior; but included fear-inducing messages. Media messages concerning health behaviors related to HPV vaccination tended to support government and parental involvement in sex education, and dismiss concerns linking vaccination to sexual activity, while also presenting the vaccine as lifesaving. Copyright © 2013 The Foundation for Professionals in Services for Adolescents. All rights reserved.

  12. Standing Concertation Committee - Ordinary Meeting on 15 January 2005

    CERN Multimedia

    2005-01-01

    This meeting was devoted to the main topics summarised below. Follow-up from the meetings of the Finance Committee and Council in December 2004 The Chairman welcomed two new SCC members representing the Staff Association: Véronique Paris and Gianni Deroma. Expressing their best wishes for the New Year, the members of the SCC took note of a report by the Chairman on the outcome of these Committee meetings and of the Director-General's staff meeting on 10 January 2005, and discussed a number of internal follow-up actions. Work planning of the SCC & TREF The SCC agreed its calendar of ordinary sessions and its draft work planning for the first half of 2005, subject to including a number of matters outstanding from 2004. The Committee discussed internal preparation for the next meeting of TREF on 4 & 5 April devoted to items concerning the current 5-Yearly Review. The SCC also took note of the provisional scheduling of TREF meetings from May to September, which will be settled by...

  13. Map showing Features and Displacements of the Scenic Drive Landslide, La Honda, California, During the Period March 31, 2005-November 5, 2006

    Science.gov (United States)

    Wells, Ray E.; Rymer, Michael J.; Prentice, Carol S.; Wheeler, Karen L.

    2006-01-01

    The Scenic Drive landslide in La Honda, San Mateo County, California began movement during the El Ni?o winter of 1997-98. Recurrent motion occurred during the mild El Ni?o winter of 2004-2005 and again during the winter of 2005-06. This report documents the changing geometry and motion of the Scenic Drive landslide in 2005-2006, and it documents changes and persistent features that we interpret to reflect underlying structural control of the landslide. We have also compared the displacement history to near-real time rainfall history at a continuously recording gauge for the period October 2004-November 2006.

  14. Therapy of MHC Class I+ and Class I- HPV 16-Associated Tumours with Cytokines, Genetically Modified Tumour Vaccines and Dendritic Cells

    Czech Academy of Sciences Publication Activity Database

    Bubeník, Jan; Šímová, Jana; Mikyšková, Romana; Vonka, V.

    2004-01-01

    Roč. 27, č. 4 (2004), s. 161D ISSN 0147-958X. [International Congress of Immunology /12./ and Annual Conference of FOCIS /4./. Montreal, 18.07.2004-23.07.2004] Institutional research plan: CEZ:AV0Z5052915 Keywords : HPV 16 * tumour vaccines * dendritic cells Subject RIV: EC - Immunology Impact factor: 1.051, year: 2004

  15. Kumutekitav arhitektuuriaasta 2005 = The Kumu-lative year in architecture 2005 / Liina Jänes, Karin Paulus

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2006-01-01

    Eesti Kultuurkapitali aastapreemia 2005 - Kumu Kunstimuuseum, arhitekt Pekka Vapaavuori. Objektipreemia - büroohoone City Plaza - Alver Trummal Arhitektid (Andres Alver, Tiit Trummal, Martin Melioranski, Indrek Rünkla). Arhitektuuri ja sisekujunduse parima terviku preemia - Jõelähtme golfiklubi, arhitekt Andres Siim, sisearhitekt Juta Lember. Tegevuaspreemia - Teddy Böckler, Tallinna raekoja pikaajalise uurimis- ja restaureerimistöö, raamatu "Tallinna raekoda : uurimine ja restaureerimine 1952-2004" eest. Teadustöö preemia - Karin Hallas-Murula, kahe eesti-soome teemalise arhitektuuriuurimuse eest: "Suurlinn Tallinn: Eliel Saarineni "Suur-Tallinna" projekt, 1913" ja "Soome-Eesti - sajand arhitektuurisuhteid"

  16. [Vaccines against hepatitis A and B in Chile].

    Science.gov (United States)

    Valenzuela, M Teresa

    2009-06-01

    The mode of transmission and epidemiological approach for hepatitis A and B are different. However, both are preventable with vaccines whose efficacy and long lasting protection has been demonstrated. This review describes the secular tendency of both infections in Chile, their risk factors that have contributed to their persistence in the country and the interventions that have been carried out to reduce the disease burden. Although the vaccine for hepatitis B was incorporated to the immunization program in 2005, the vaccine for hepatitis A persists in the list of interventions that must be assumed with priority by the Ministry of Health. If Chilean health authorities pretend to reach the enteric disease indicators of developed countries, they must accelerate the epidemiological transition towards the elimination of hepatitis A.

  17. Stratus Ocean Reference Station (20 deg. S, 85 deg. W) : Mooring Recovery and Deployment Cruise, R/V Ronald H. Brown Cruise 05-05, September 26, 2005-October 21, 2005

    National Research Council Canada - National Science Library

    Hutto, Lara; Weller, Robert; Lord, Jeff; Smith, Jason; Bouchard, Paul; Fairall, Chris; Pezoa, Sergio; Bariteau, Ludovic; Lundquist, Jessica; Ghate, Virendra

    2006-01-01

    .... During the October 2005 cruise of NOAA's R/V Ronald H. Brown to the ORS Stratus site, the primary activities were recovery of the WHOl surface mooring that had been deployed in December 2004, deployment of a new...

  18. Dip-Test Internal Stress and the Composite Model of Creep Deformation

    Czech Academy of Sciences Publication Activity Database

    Dobeš, Ferdinand; Orlová, Alena

    2005-01-01

    Roč. 482, - (2005), s. 291-294 ISSN 0255-5476. [Materials Structure & Micromechanics of Fracture /4./. Brno, 23.06.2004-25.06.2004] R&D Pro jects: GA AV ČR(CZ) IAA2041202 Institutional research plan: CEZ:AV0Z20410507 Keywords : creep * internal stress * subgrain Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.399, year: 2005

  19. Trends in energy 2005. Utility value chain optimisation

    International Nuclear Information System (INIS)

    Fens, T.; IJsbrandy, C.; Van Druten, A.; De Rooij, S.; Van de Rhee, R.; Rookmaaker, J.; Spaans, P.; Pulles, L.

    2005-01-01

    Trends in Energy 2005 has been written around a number of events that were observed in research that was carried out in 2004: the full market opening mid 2004, the likely unbundling of distribution networks in some form, security of supply issues, fuel mix in the generation portfolio and the associated investment strategies, the rise of intelligent metering, certificates of origin for electricity, the most likely movement towards the suppliers model ('leveranciersmodel') and finally emissions management emerging from Kyoto that is coming into force. These events have been interpreted from the perspective of the units in the energy value chain: production, trade, transmission, distribution, metering and sales, the latter is the mostly the direct contact for the end customer

  20. Antipneumococcal vaccination

    Directory of Open Access Journals (Sweden)

    Gian Vincenzo Zuccotti

    2013-06-01

    Full Text Available Streptococcus pneumoniae (SP is a gram-positive bacterium with more than 90 known serotypes causing around 11% of all deaths worldwide in children aged 1-59 months. A new era in prevention of SP-related diseases started in at the beginning of 2000s when a 7-valent pneumococcal conjugate vaccine (PCV7 was recommended as the vaccine of choice in pediatric age. PCV7 dramatically reduced invasive pneumococcal diseases (IPD among children with indirect effects noted among other age groups as well. However, thanks to a strict surveillance network, an increase in non-vaccine serotypes (NVTs causing IPD was noted worldwide and in late 2000s a new second generation vaccine (13-valent pneumococcal conjugate vaccine-PCV13 with an expanded serotype coverage was licensed. Due to the lack of solid effectiveness data, up to know it is difficult to predict how the composition of NVTs will change after the large-scale introduction of PCV13 or whether the characteristics of the serotypes will change. Long-term surveillance of both IPD, pneumonia, acute otitis media and carriage will be crucial to ascertain whether these second generation vaccines are having the desired effect of reducing the incidence of diseases in the long term. Proceedings of the 9th International Workshop on Neonatology · Cagliari (Italy · October 23rd-26th, 2013 · Learned lessons, changing practice and cutting-edge research

  1. Construction and biological characterization of artificial recombinants between a wild type flavivirus (Kunjin) and a live chimeric flavivirus vaccine (ChimeriVax-JE).

    Science.gov (United States)

    Pugachev, Konstantin V; Schwaiger, Julia; Brown, Nathan; Zhang, Zhen-xi; Catalan, John; Mitchell, Frederick S; Ocran, Simeon W; Rumyantsev, Alexander A; Khromykh, Alexander A; Monath, Thomas P; Guirakhoo, Farshad

    2007-09-17

    Although the theoretical concern of genetic recombination has been raised related to the use of live attenuated flavivirus vaccines [Seligman, Gould, Lancet 2004;363:2073-5], it has little foundation [e.g., Monath TP, Kanesa-Thasan N, Guirakhoo F, Pugachev K, Almond J, Lang J, et al. Vaccine 2005;23:2956-8]. To investigate biological effects of recombination between a chimeric yellow fever (YF) 17D/Japanese encephalitis (JE) vaccine virus (ChimeriVax-JE) and a wild-type flavivirus Kunjin (KUN-cDNA), the prM-E envelope protein genes were swapped between the two viruses, resulting in new YF 17D/KUN(prM-E) and KUN/JE(prM-E) chimeras. The prM-E genes are easily exchangeable between flavivirues, and thus the exchange was expected to yield the most replication-competent chimeras, while other rationally designed recombinants would be more likely to be crippled or non-viable. The new chimeras proved highly attenuated in comparison with the KUN-cDNA parent, as judged by plaque size and growth kinetics in cell culture, low viremia in hamsters, and reduced neurovirulence/neuroinvasiveness in mice. These data provide strong experimental evidence that the potential of recombinants, should they ever emerge, to cause disease or spread (compete in nature with wild-type flaviviruses) would be indeed extremely low.

  2. Are Recent Medical Graduates More Skeptical of Vaccines?

    Directory of Open Access Journals (Sweden)

    Anthony Damico

    2013-04-01

    Full Text Available Rates of delay and refusal of recommended childhood vaccines are increasing in many U.S. communities. Children’s health care providers have a strong influence on parents’ knowledge, attitudes, and beliefs about vaccines. Provider attitudes towards immunizations vary and affect their immunization advocacy. One factor that may contribute to this variability is their familiarity with vaccine-preventable diseases and their sequelae. The purpose of this study was to investigate the association of health care provider year of graduation with vaccines and vaccine-preventable disease beliefs. We conducted a cross sectional survey in 2005 of primary care providers identified by parents of children whose children were fully vaccinated or exempt from one or more school immunization requirements. We examined the association of provider graduation cohort (5 years with beliefs on immunization, disease susceptibility, disease severity, vaccine safety, and vaccine efficacy. Surveys were completed by 551 providers (84.3% response rate. More recent health care provider graduates had 15% decreased odds of believing vaccines are efficacious compared to graduates from a previous 5 year period; had lower odds of believing that many commonly used childhood vaccines were safe; and 3.7% of recent graduates believed that immunizations do more harm than good. Recent health care provider graduates have a perception of the risk-benefit balance of immunization, which differs from that of their older counterparts. This change has the potential to be reflected in their immunization advocacy and affect parental attitudes.

  3. Measuring energy conservation on Nova Scotia (NS) farms: A 2004 to 2011 comparison

    International Nuclear Information System (INIS)

    Bailey, J.A.; Duinker, P.; Amyotte, P.; Adams, M.; Khan, F.

    2016-01-01

    Many jurisdictions, including Nova Scotia (NS), have implemented policies and programs around energy. The NS government has targeted energy efficiency and more renewable energy as two main policy areas. The NS Department of Agriculture has taken initiative to provide support to implement energy conservation, energy efficiency and renewable energy opportunities in recent years but have these programs and policies been effective? A baseline energy use survey was conducted in 2005 and responses from mail surveys in 2012 (n = 273, 11.4% response rate) were used to measure the change in NS farm energy use data reported for 2004 and 2011. There have been significant reductions in energy use on NS farms. On average, NS farmers spent $8790 on energy expenses in 2011 compared to $11,228 in 2004. Adjusting for inflation, this is a 32% decrease, despite energy commodity pricing increases beyond the inflation rate. This is likely due to a decrease in energy use and a shift from gasoline use to diesel use. By the end of 2012, 36.0% of NS farmers (more than 860) had received some level of support to evaluate their energy options. This includes 410 energy audits compared to only 36 by the end of 2005. - Highlights: • Nova Scotia farmers decreased their energy costs by 32% between 2004 and 2011. • Energy reductions were likely due to decreased energy use and a shift in fuel use. • An estimated 374 NS farms had an energy audit between 2005 and 2012.

  4. Üldine kaubandus (toidukaupade turg) : toidukaupade väliskaubanduse bilanss [2003-2004] / Õrne Pill, Liia Laanes, Ene Maadvere

    Index Scriptorium Estoniae

    Pill, Õrne

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 55-65. Põllumajandussaaduste ekspordimaht kasvas eelmise aasta sama perioodiga võrreldes 5,1% ning impordimaht vähenes 1,8%, kaubandusbilansi negatiivne saldo moodustas 4507,7 mln krooni. Diagrammid

  5. Vaccines and IP Rights: A Multifaceted Relationship.

    Science.gov (United States)

    Durell, Karen

    2016-01-01

    Just as there are many forms of vaccines and components to vaccines-particular compositions, delivery systems, components, and distribution networks-there are a variety of intellectual property (IP) protections applicable for vaccines. IP rights such as patent, copyright, trademarks, plant breeders' rights, and trade secrets may all be applicable to vaccines. Thus, discussion of IP rights and vaccines should not begin and end with the application of one IP right to a vaccine. The discussion should engage considerations of multiple IP rights applicable to a vaccine and how these can be utilized in an integrated manner in a strategy aimed at supporting the development and distribution of the vaccine. Such an approach to IP rights to vaccines allows for the integrated rights to be considered in light of the justifications for protecting vaccines with IP rights, as well as the issues relating to specific IP rights for vaccines, such as compulsory license regimes, available humanitarian purpose IP credits, etc. To view vaccines as the subject of multiple IP protections involves a refocusing, but the outcome can provide significant benefits for vaccine development and distribution.

  6. MicroMAPS CO Measurements over North America and Europe during Summer-Fall 2004

    Science.gov (United States)

    Connors, Vickie S.; Hopkins, Patrick E.; Reichle, Henry G., Jr.; Morrow, William H.; McMillan, Wallace; Sandy, Mary L.

    2006-01-01

    The MicroMAPS instrument is a nadir-viewing, gas filter-correlated radiometer which operating in the 4.67 micrometer fundamental band of carbon monoxide. Originally designed and built for a space mission, this CO remote sensor is being flown in support of satellite validation and science instrument demonstrations for potential UAV applications. The MicroMAPS instrument system, as flown on Proteus, was designed by a senior student design project in the Aerospace Engineering Department, Virginia Tech, in Blacksburg, VA. and then revised by Systems Engineers at NASA Langley. The final instrument system was integrated and tested at NASA LaRC, in partnership with Scaled Composites and Virginia Space Grant Consortium (VSGC). VSGC supervised the fabrication of the nacelle that houses the instrument system on the right rear tail boom of Proteus. Full system integration and flight testing was performed at Scaled Composites, in Mojave, in June 2004. Its successful performance enabled participation in four international science missions on Proteus: in 2004, INTEX -NA over eastern North America in July, ADRIEX over the Mediterranean region and EAQUATE over the United Kingdom region in September,and TWP-ICE over Darwin, Australia and the surrounding oceans in Jan-Feb 2006. These flights resulted in nearly 300 hours of data. In parallel with the engineering developments, theoretical radiative transfer models were developed specifically for the MicroMAPS instrument system at the University of Virginia, Mechanical Engineering Department by a combined undergraduate and graduate student team. With technical support from Resonance Ltd. in June 2005, the MicroMAPS instrument was calibrated for the conditions under which the Summer-Fall 2004 flights occurred. The analyses of the calibration data, combined with the theoretical radiative transfer models, provide the first data reduction for the science flights reported here. These early results and comparisons with profile data from the

  7. Annual report on the effluent control of low level liquid water in Tokai Works. FY2004

    International Nuclear Information System (INIS)

    Takeishi, Minoru; Miyagawa, Naoto; Watanabe, Hitoshi

    2005-08-01

    This report was written about the effluent control of low level liquid waste in JNC Tokai Works Fiscal Year 2004, from 1st April 2004 to 31th March 2005. In this period, the quantities and concentrations of radioactivity in liquid waste from Tokai Works were under the discharge limits of 'Safety Regulations for the Tokai Reprocessing Plant' and regulations of government. (author)

  8. US Military Service Members Vaccinated Against Smallpox in 2003 and 2004 Experience a Slightly Higher Risk of Hospitalization Postvaccination

    Science.gov (United States)

    2008-01-01

    vaccination on the health of young adults . Published by Elsevier Ltd. 1. Introduction Through extensive vaccination efforts [1], smallpoxwas globally...Disorders of lipoid metabolism 74 0.1 17 0.0 2.43 1.42, 4.18 250 Diabetes mellitus 23 0.0 2 0.0 244 Acquired hypothyroidism 19 0.0 2 0.0 278 Obesity and...and influenza elicited during primary versus recent or distant secondary smallpox vaccination of adults . Vaccine 2006;24:6913–23. REPORT DOCUMENTATION

  9. Frequency of medically attended adverse events following tetanus and diphtheria toxoid vaccine in adolescents and young adults: a Vaccine Safety Datalink study

    Directory of Open Access Journals (Sweden)

    Naleway Allison

    2009-10-01

    Full Text Available Abstract Background Local reactions are the most commonly reported adverse events following tetanus and diphtheria toxoid (Td vaccine and the risk of local reactions may increase with number of prior Td vaccinations. Methods To estimate the risk of medically attended local reactions following Td vaccination in adolescents and young adults we conducted a six-year retrospective cohort study assessing 436,828 Td vaccinations given to persons 9 through 25 years of age in the Vaccine Safety Datalink population from 1999 through 2004. Results Overall, the estimated risk of a medically attended local reaction was 3.6 events per 10,000 Td vaccinations. The lowest risk (2.8 events per 10,000 vaccinations was found in the 11 to 15 year old age group. In comparison with that group, the event risks were significantly higher in both the 9 to 10 and 21 to 25 year old age groups. The risk of a local reaction was significantly higher in persons who had received another tetanus and diphtheria toxoid containing vaccine (TDCV in the previous five years (incidence rate ratio, 2.9; 95% confidence interval, 1.2 to 7.2. Twenty-eight percent of persons with a local reaction to Td vaccine were prescribed antibiotics. Conclusion Medically attended local reactions were uncommon following Td vaccination. The risk of those reactions varied by age and by prior receipt of TDCVs. These findings provide a point of reference for future evaluations of the safety profile of newer vaccines containing tetanus or diphtheria toxoid.

  10. The 2005 energy situation in France

    International Nuclear Information System (INIS)

    2006-04-01

    After a year 2004 of economic revival, 2005 shows a crisis of the energy prices and a slow economic activity. The year is characterized by again a petroleum consumption decrease, a poor hydro electric power which generates an increase of the fossil fuels consumption and finally a little increase of the primary energy consumption and CO 2 emissions. It provides more details on the economic and energy context, on the energy consumption and production and on the carbon dioxide emissions from the energy. (A.L.B.)

  11. The Swedish Energy Market 2005

    International Nuclear Information System (INIS)

    2005-10-01

    The Swedish Energy Market, 2005 is an annual publication that presents information and statistics on the network based energy markets in Sweden, i.e. the markets for electricity, natural gas and district heating. It also provides an overview of the issues that have arisen on these markets during the second half of 2004 and the first half of 2005. Considerable work is being carried out in the EU on creating a single market for electricity and natural gas. This publication therefore describes expansion of the Swedish market towards a Nordic and a European market. The publication normally includes a theme chapter, describing some event of particular interest for the Swedish energy market during the year. This year, the theme chapter is devoted to the Storm Gudrun, which struck the south of the country at the beginning of January, and its effects on electricity supply throughout the country. The chapter is based on the report submitted to the Government by the Energy Markets Inspectorate in the spring of 2005, and also includes a summary of the Inspectorate's proposals for measures to improve the security of electricity transmission. Energy in Sweden, which is another of the Swedish Energy Agency's annual publications, provides information and statistics on the development of the entire Swedish energy system

  12. Cohort profile update: 2004 Pelotas (Brazil) Birth Cohort Study. Body composition, mental health and genetic assessment at the 6 years follow-up.

    Science.gov (United States)

    Santos, Iná S; Barros, Aluísio J D; Matijasevich, Alicia; Zanini, Roberta; Chrestani Cesar, Maria Aurora; Camargo-Figuera, Fabio Alberto; Oliveira, Isabel O; Barros, Fernando C; Victora, Cesar G

    2014-10-01

    This is an update of the 2004 Pelotas Birth Cohort profile, originally published in 2011. In view of the high prevalence of overweight and mental health problems among Brazilian children, together with the availability of state-of-the-art equipment to assess body composition and diagnostic tests for mental health in childhood, the main outcomes measured in the fifth follow-up (mean age 6.8 years) included child body composition, mental health and cognitive ability. A total of 3722 (90.2%) of the original mothers/carers were interviewed and their children examined in a clinic where they underwent whole-body dual X-ray absorptiometry (DXA), air displacement plethysmography and a 3D photonic scan. Saliva samples for DNA were obtained. Clinical psychologists applied the Development and Well-Being Assessment questionnaire and the Wechsler Intelligence Scale for Children to all children. Results are being compared with those of the two earlier cohorts to assess the health effects of economic growth and full implementation of public policies aimed at reducing social inequalities in the past 30 years. For further information visit the programme website at [http://www.epidemio-ufpel.org.br/site/content/coorte_2004/questionarios.php]. Applications to use the data should be made by contacting 2004 cohort researchers and filling in the application form available at [http://www.epidemio-ufpel.org.br/site/content/estudos/formularios.php]. © The Author 2014; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

  13. Reproductive Ecology of Yakima River Hatchery and Wild Spring Chinook; Yakima/Klickitat Fisheries Project Monitoring and Evaluation, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Knudsen, Curtis M. (Oncorh Consulting, Olympia, WA); Schroder, Steven L. (Washington Department of Fish and Wildlife, Olympia, WA); Johnston, Mark V. (yakama Nation, Toppenish, WA)

    2005-05-01

    This report is intended to satisfy two concurrent needs: (1) provide a contract deliverable from Oncorh Consulting to the Washington Department of Fish and Wildlife (WDFW), with emphasis on identification of salient results of value to ongoing Yakima/Klickitat Fisheries Project (YKFP) planning and (2) summarize results of research that have broader scientific relevance. This is the fourth in a series of reports that address reproductive ecological research and monitoring of spring chinook populations in the Yakima River basin. This annual report summarizes data collected between April 1, 2004 and March 31, 2005 and includes analyses of historical baseline data, as well. Supplementation success in the Yakima Klickitat Fishery Project's (YKFP) spring chinook (Oncorhynchus tshawytscha) program is defined as increasing natural production and harvest opportunities, while keeping adverse ecological interactions and genetic impacts within acceptable bounds (Busack et al. 1997). Within this context demographics, phenotypic traits, and reproductive ecology have significance because they directly affect natural productivity. In addition, significant changes in locally adapted traits due to hatchery influence, i.e. domestication, would likely be maladaptive resulting in reduced population productivity and fitness (Taylor 1991; Hard 1995). Thus, there is a need to study demographic and phenotypic traits in the YKFP in order to understand hatchery and wild population productivity, reproductive ecology, and the effects of domestication (Busack et al. 1997). Tracking trends in these traits over time is also a critical aspect of domestication monitoring (Busack et al. 2004) to determine whether trait changes have a genetic component and, if so, are they within acceptable limits. The first chapter of this report compares first generation hatchery and wild upper Yakima River spring chinook returns over a suite of life-history, phenotypic and demographic traits. The second

  14. Age groups and spread of influenza: implications for vaccination strategy

    Directory of Open Access Journals (Sweden)

    Hsieh Ying-Hen

    2010-04-01

    Full Text Available Abstract Background The unpredictable nature of the potentially devastating impact of 2009 pH1N1 influenza pandemic highlights the need for pandemic preparedness planning, where modeling studies could be most useful for simulations of possible future scenarios. Methods A compartmental model with pre-symptomatic and asymptomatic influenza infections is proposed which incorporates age groups as well as intervention measures such as age-specific vaccination, in order to study spread of influenza in a community. Results We derive the basic reproduction number and other effective reproduction numbers under various intervention measures. For illustration, we make use of the Pneumonia and Influenza (P&I mortality data and vaccination data of the very young (age 0-2 and the very old (age >64 during 2004-2005 Taiwan winter influenza season to fit our model and to compute the relevant reproduction numbers. The reproduction number for this winter flu season is estimated to be slightly above one (~1.0001. Conclusions Comparatively large errors in fitting the P&I mortality data of the elderly (>64 were observed shortly after winter school closings in January, which may indicate the impact of younger, more active age groups transmitting influenza to other age groups outside of the school settings; in particular, to the elderly in the households. Pre-symptomatic infections seemed to have little effect on the model fit, while asymptomatic infection by asymptomatic infectives has a more pronounced impact on the model fit for the elderly mortality, perhaps indicating a larger role in disease transmission by asymptomatic infection. Simulations indicate that the impact of vaccination on the disease incidence might not be fully revealed in the change (or the lack thereof in the effective reproduction number with interventions, but could still be substantial. The estimated per contact transmission probability for susceptible elderly is significantly higher than that

  15. Cohortstudie arbeid, verzuim en gezondheid (AVG) : methodologie en eerste resultaten 2004-2006

    NARCIS (Netherlands)

    Ybema, J.F.; Sanders, J.; Vroome, E.M.M. de

    2006-01-01

    De cohortstudie Arbeid, Verzuim en Gezondheid (AVG) is een onderzoek dat TNO verricht in samenwerking met het ministerie van VWS. De AVG is een longitudinaal studie met drie jaarlijkse metingen (in 2004, 2005 en 2006) onder werknemers. Het doel is te onderzoeken hoe het gedrag van werknemers,

  16. Morocco. Act no. 12-02 on civil liability for nuclear damage. Promulgated on 7 january 2005. Chapter 1. General provisions

    International Nuclear Information System (INIS)

    Anon.

    2005-01-01

    Three texts concern Morocco with the Act on civil liability for Nuclear damage (2005), International Atomic energy Agency with the code of conduct on the safety of research reactors (2004), United Nations with U.N. Security Council Resolution 1540 (2004). (N.C.)

  17. Habitat Evaluation Procedures (HEP) Report; Calispell Creek Project, Technical Report 2004-2005.

    Energy Technology Data Exchange (ETDEWEB)

    Entz, Ray

    2005-02-01

    On July 13, 2004, the Habitat Evaluation Procedure (HEP) was used to determine baseline habitat suitability on the Calispell Creek property, an acquisition completed by the Kalispel Tribe of Indians in February 2004. Evaluation species and appropriate models include Canada goose, mallard, muskrat, yellow warbler, and white-tailed deer. Habitat Suitability Index (HSI) values were visually estimated and agreed upon by all HEP team members. The Calispell Creek Project provides a total of 138.17 Habitat Units (HUs) for the species evaluated. Emergent wetland habitat provides 5.16 HUs for mallard and muskrat. Grassland provides 132.02 HUs for mallard and Canada goose. Scrub-shrub vegetation provides 0.99 HUs for yellow warbler and white-tailed deer. The objective of using HEP at the Calispell Creek Project and other protected properties is to document the quality and quantity of available habitat for selected wildlife species. In this way, HEP provides information on the relative value of the same area at future points in time so that the effect of management activities on wildlife habitat can be quantified. When combined with other tools, the baseline HEP will be used to determine the most effective on-site management, restoration, and enhancement actions to increase habitat suitability for targeted species. The same process will be replicated every five years to quantitatively evaluate the effectiveness of management strategies in improving and maintaining habitat conditions while providing additional crediting to BPA for enhanced habitat values.

  18. Habitat Evaluation Procedures (HEP) Report : West Beaver Lake, 2004-2005 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Entz, Ray

    2005-02-01

    On September 7, 2004, the Habitat Evaluation Procedure (HEP) was used to determine baseline habitat suitability on the West Beaver Lake property, an acquisition completed by the Kalispel Tribe of Indians in September 2004. Evaluation species and appropriate models include bald eagle, black-capped chickadee, mallard, muskrat, and white-tailed deer. Habitat Suitability Index (HSI) values were visually estimated and agreed upon by all HEP team members. The West Beaver Lake Project provides a total of 103.08 Habitat Units (HUs) for the species evaluated. Emergent wetland habitat provides 7.17 HUs for mallard and muskrat. Conifer forest habitat provides 95.91 HUs for bald eagle, black-capped chickadee, mallard, and white-tailed deer. The objective of using HEP at the West Beaver Lake Project and other protected properties is to document the quality and quantity of available habitat for selected wildlife species. In this way, HEP provides information on the relative value of the same area at future points in time so that the effect of management activities on wildlife habitat can be quantified. When combined with other tools, the baseline HEP will be used to determine the most effective on-site management, restoration, and enhancement actions to increase habitat suitability for targeted species. The same process will be replicated every five years to quantitatively evaluate the effectiveness of management strategies in improving and maintaining habitat conditions while providing additional crediting to BPA for enhanced habitat values.

  19. First quarter 2005 sales data

    International Nuclear Information System (INIS)

    2005-04-01

    This press release brings information on the AREVA group sales data. First quarter 2005 sales for the group were 2,496 millions of euros, up 3,6% year-on-year from 2,41 millions. The change in foreign exchange rates between the two periods show a negative impact of 22 millions euros, which is much lower than in the first quarter of 2004. It analyzes also in more details the situation of the front end, the reactors and service division, the back end division, the transmission and distribution division and the connectors division. (A.L.B.)

  20. Clinical evaluation of dermatophytosis in patients referred to dermatologic department of Bu-Ali Sina Hospital in Qazvin in Iran 2004-2005

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Aghamirian

    2007-02-01

    Full Text Available Background: Dermatophytosis is a prevalent mycologic skin disease which is a widespread important health problem in the world. The ecology and etiology of the disease are important issues for its control. Methods: In a descriptive study, 341 patients with suspected dermatophytosis were examined over a period of one year (2004-2005. Skin, hair and nail samples were evaluated by to direct microscopic examination using potassium hydroxide (KOH the specimens were cultured in sabouraud dextrose agar. In some cases, differential tests such as corn meal agar, urease and hair perforation were used for recognizing the isolated dermatophytes. Results: A total of 116 dermatophytes (34% were isolated. Tinea cruris (31.9% was the most common type of infection, followed by tinea corporis (20.7%, tinea pedis (19%, tinea unguium (11.2%, tinea faciei (7.7%, tinea manuum (5.2%, tinea capitis (4.3%. Epidermophyton floccosum was the most frequent isolated dermatophyte (32.8%. Also Dermatophytosis was more frequent in male gender. Conclusion: The anthropophilic species, E. floccosum, was the most common causative dermatophyte of tinea in Qazvin and the most common clinical type of dermatophytosis was Tinea cruris.

  1. Percutaneous Vaccination as an Effective Method of Delivery of MVA and MVA-Vectored Vaccines.

    Directory of Open Access Journals (Sweden)

    Clement A Meseda

    Full Text Available The robustness of immune responses to an antigen could be dictated by the route of vaccine inoculation. Traditional smallpox vaccines, essentially vaccinia virus strains, that were used in the eradication of smallpox were administered by percutaneous inoculation (skin scarification. The modified vaccinia virus Ankara is licensed as a smallpox vaccine in Europe and Canada and currently undergoing clinical development in the United States. MVA is also being investigated as a vector for the delivery of heterologous genes for prophylactic or therapeutic immunization. Since MVA is replication-deficient, MVA and MVA-vectored vaccines are often inoculated through the intramuscular, intradermal or subcutaneous routes. Vaccine inoculation via the intramuscular, intradermal or subcutaneous routes requires the use of injection needles, and an estimated 10 to 20% of the population of the United States has needle phobia. Following an observation in our laboratory that a replication-deficient recombinant vaccinia virus derived from the New York City Board of Health strain elicited protective immune responses in a mouse model upon inoculation by tail scarification, we investigated whether MVA and MVA recombinants can elicit protective responses following percutaneous administration in mouse models. Our data suggest that MVA administered by percutaneous inoculation, elicited vaccinia-specific antibody responses, and protected mice from lethal vaccinia virus challenge, at levels comparable to or better than subcutaneous or intramuscular inoculation. High titers of specific neutralizing antibodies were elicited in mice inoculated with a recombinant MVA expressing the herpes simplex type 2 glycoprotein D after scarification. Similarly, a recombinant MVA expressing the hemagglutinin of attenuated influenza virus rgA/Viet Nam/1203/2004 (H5N1 elicited protective immune responses when administered at low doses by scarification. Taken together, our data suggest that

  2. Percutaneous Vaccination as an Effective Method of Delivery of MVA and MVA-Vectored Vaccines.

    Science.gov (United States)

    Meseda, Clement A; Atukorale, Vajini; Kuhn, Jordan; Schmeisser, Falko; Weir, Jerry P

    2016-01-01

    The robustness of immune responses to an antigen could be dictated by the route of vaccine inoculation. Traditional smallpox vaccines, essentially vaccinia virus strains, that were used in the eradication of smallpox were administered by percutaneous inoculation (skin scarification). The modified vaccinia virus Ankara is licensed as a smallpox vaccine in Europe and Canada and currently undergoing clinical development in the United States. MVA is also being investigated as a vector for the delivery of heterologous genes for prophylactic or therapeutic immunization. Since MVA is replication-deficient, MVA and MVA-vectored vaccines are often inoculated through the intramuscular, intradermal or subcutaneous routes. Vaccine inoculation via the intramuscular, intradermal or subcutaneous routes requires the use of injection needles, and an estimated 10 to 20% of the population of the United States has needle phobia. Following an observation in our laboratory that a replication-deficient recombinant vaccinia virus derived from the New York City Board of Health strain elicited protective immune responses in a mouse model upon inoculation by tail scarification, we investigated whether MVA and MVA recombinants can elicit protective responses following percutaneous administration in mouse models. Our data suggest that MVA administered by percutaneous inoculation, elicited vaccinia-specific antibody responses, and protected mice from lethal vaccinia virus challenge, at levels comparable to or better than subcutaneous or intramuscular inoculation. High titers of specific neutralizing antibodies were elicited in mice inoculated with a recombinant MVA expressing the herpes simplex type 2 glycoprotein D after scarification. Similarly, a recombinant MVA expressing the hemagglutinin of attenuated influenza virus rgA/Viet Nam/1203/2004 (H5N1) elicited protective immune responses when administered at low doses by scarification. Taken together, our data suggest that MVA and MVA

  3. Hepatitis B vaccination coverage and risk factors associated with incomplete vaccination of children born to hepatitis B surface antigen-positive mothers, Denmark, 2006 to 2010.

    Science.gov (United States)

    Kunoee, Asja; Nielsen, Jens; Cowan, Susan

    2016-01-01

    In Denmark, universal screening of pregnant women for hepatitis B has been in place since November 2005, with the first two years as a trial period with enhanced surveillance. It is unknown what the change to universal screening without enhanced surveillance has meant for vaccination coverage among children born to hepatitis B surface antigen (HBsAg)-positive mothers and what risk factors exist for incomplete vaccination. This retrospective cohort study included 699 children of mothers positive for HBsAg. Information on vaccination and risk factors was collected from central registers. In total, 93% (651/699) of the children were vaccinated within 48 hours of birth, with considerable variation between birthplaces. Only 64% (306/475) of the children had received all four vaccinations through their general practitioner (GP) at the age of two years, and 10% (47/475) of the children had received no hepatitis B vaccinations at all. Enhanced surveillance was correlated positively with coverage of birth vaccination but not with coverage at the GP. No or few prenatal examinations were a risk factor for incomplete vaccination at the GP. Maternity wards and GPs are encouraged to revise their vaccination procedures and routines for pregnant women, mothers with chronic HBV infection and their children.

  4. In-Depth Characterization of Live Vaccines Used in Europe for Oral Rabies Vaccination of Wildlife.

    Directory of Open Access Journals (Sweden)

    Florence Cliquet

    Full Text Available Although rabies incidence has fallen sharply over the past decades in Europe, the disease is still present in Eastern Europe. Oral rabies immunization of wild animal rabies has been shown to be the most effective method for the control and elimination of rabies. All rabies vaccines used in Europe are modified live virus vaccines based on the Street Alabama Dufferin (SAD strain isolated from a naturally-infected dog in 1935. Because of the potential safety risk of a live virus which could revert to virulence, the genetic composition of three commercial attenuated live rabies vaccines was investigated in two independent laboratories using next genome sequencing. This study is the first one reporting on the diversity of variants in oral rabies vaccines as well as the presence of a mix of at least two different variants in all tested batches. The results demonstrate the need for vaccine producers to use new robust methodologies in the context of their routine vaccine quality controls prior to market release.

  5. Adopting the international financial reporting standards: a positive impact on 2004 income and consolidated equity

    International Nuclear Information System (INIS)

    Mallet, O.

    2005-03-01

    This document provides preliminary information on the quantitative impact of transition to the International Financial Reporting Standards (IFRS) on AREVA 2004 financial position, in accordance with AMF recommendations regarding financial communications during the transition period.The basis for preparing 2004 information on transition to the IFRS comes from: the International Accounting Standards (IAS)/IFRS, as approved by the European Union. The impact of IAS 32/39 and IFRS 4 will not be recognized in shareholders equity until January 1, 2005; AREVA anticipation of the resolution of technical issues and ongoing projects under discussion by the International Accounting Standards Board (IASB) and the International Financial Reporting Interpretations Committee (IFRIC). Uncertainty factors on practical methods for applying certain standards and ongoing interpretations by IFRIC and regulatory organizations could impact the exactness of restatements identified at this stage. For all of these reasons, it is conceivable that the opening balance sheet at January 1, 2004, as presented in this document, will not be the balance sheet actually used to establish the consolidated financial statements for 2005. (author)

  6. Discrepancies between Abstracts Presented at International Association for Dental Research Annual Sessions from 2004 to 2005 and Full-Text Publication.

    Science.gov (United States)

    Prasad, Soni; Lee, Damian J; Yuan, Judy Chia-Chun; Barao, Valentim A R; Shyamsunder, Nodesh; Sukotjo, Cortino

    2012-01-01

    Purpose. The purpose of this study was to evaluate the discrepancies between abstracts presented at the IADR meeting (2004-2005) and their full-text publication. Material and Methods. Abstracts from the Prosthodontic Section of IADR meeting were obtained. The following information was collected: abstract title, number of authors, study design, statistical analysis, outcome, and funding source. PubMed was used to identify the full-text publication of the abstracts. The discrepancies between the abstract and the full-text publication were examined, categorized as major and minor discrepancies, and quantified. The data were collected and analyzed using descriptive analysis. Frequency and percentage of major and minor discrepancies were calculated. Results. A total of 109 (95.6%) articles showed changes from their abstracts. Seventy-four (65.0%) and 105 (92.0%) publications had at least one major and one minor discrepancies, respectively. Minor discrepancies were more prevalent (92.0%) than major discrepancies (65.0%). The most common minor discrepancy was observed in the title (80.7%), and most common major discrepancies were seen in results (48.2%). Conclusion. Minor discrepancies were more prevalent than major discrepancies. The data presented in this study may be useful to establish a more comprehensive structured abstract requirement for future meetings.

  7. Poverty decline, agricultural wages, and nonfarm employment in rural India : 1983-2004

    NARCIS (Netherlands)

    Lanjouw, Peter; Murgai, Rinku

    We analyze five rounds of National Sample Survey data covering 1983, 1987/1988, 1993/1994, 1999/2000, and 2004/2005 to explore the relationship between rural diversification and poverty. Poverty in rural India has declined at a modest rate during this time period. We provide region-level estimates

  8. Considerations of strategies to provide influenza vaccine year round

    NARCIS (Netherlands)

    Lambach, Philipp; Alvarez, Alba Maria Ropero; Hirve, Siddhivinayak; Ortiz, Justin R.; Hombach, Joachim; Verweij, Marcel; Hendriks, Jan; Palkonyay, Laszlo; Pfleiderer, Michael

    2015-01-01

    There is potential for influenza vaccine programmes to make a substantial impact on severe disease in low-resource settings, however questions around vaccine composition and programmatic issues will require special attention. Some countries may benefit from immunization programmes that provide

  9. Compositional Trends in Acid Fluids of Copahue Volcano, Argentina: Evidence for a failed eruption in 2004?

    Science.gov (United States)

    Kading, T. J.; Brophy, M.; Varekamp, J. C.

    2008-12-01

    The concentrations and fluxes of major, minor, and trace elements in the crater lake, volcanic spring, and acidified watershed of Copahue Volcano, Neuquen province, Argentina, have been monitored over the last decade. The 2000 Copahue eruption resulted in enhanced S/Cl, increased concentrations and fluxes of rock forming elements (especially Mg and Na) with strongly raised Mg/Cl and Mg/K values. The degree of LREE enrichment decreased and a pronounced Eu anomaly developed in the fluids (Eu/Eu*> rock values). These patterns are explained as the result of hot acid fluid attack on newly intruded magma, with early dissolution of olivine (Mg spike) and plagioclase (Na spike, Eu anomaly). Similar compositional changes were observed in water samples taken in November, 2004, but no eruption occurred. These may be the signals of a small magmatic intrusion into the hydrothermal system, which failed to continue into an eruption. The compositional changes of Copahue volcanic fluids over the last decade will be discussed in the context of chemical signals of an actual and a suspected 'failed eruption'.

  10. Tervise enesehinnangu sotsiaalmajanduslikud erinevused Eestis : Euroopa sotsiaaluuring 2004 / Ülle Sildever, Kersti Pärna, Inge Ringmets

    Index Scriptorium Estoniae

    Sildever, Ülle

    2008-01-01

    Euroopa sotsiaaluuringust, mis korraldati Eestis ajavahemikul novembrist 2004 kuni jaanuarini 2005 ja mille käigus uuriti 35-54aastaste täiskasvanute tervise enesehinnangu sotsiaal-majanduslikke erinevusi. Lisatud statistilised tabelid

  11. Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis

    DEFF Research Database (Denmark)

    Pauli, Gabrielle; Larsen, Tina H; Rak, Sabina

    2008-01-01

    BACKGROUND: Recombinant DNA technology has the potential to produce allergen-specific immunotherapy vaccines with defined composition. OBJECTIVE: To evaluate the effectiveness of a new recombinant birch pollen allergen vaccine in patients with birch pollen allergy. METHODS: A multicenter, randomi......-treated group. CONCLUSION: The rBet v 1-based vaccine was safe and effective in treating birch pollen allergy, and induced a highly specific immune response.......BACKGROUND: Recombinant DNA technology has the potential to produce allergen-specific immunotherapy vaccines with defined composition. OBJECTIVE: To evaluate the effectiveness of a new recombinant birch pollen allergen vaccine in patients with birch pollen allergy. METHODS: A multicenter......, randomized, double-blind, placebo-controlled trial was undertaken to compare the following 3 vaccines in 134 adults with birch pollen allergy: recombinant birch pollen allergen vaccine (rBet v 1a), licensed birch pollen extract, natural purified birch pollen allergen (nBet v 1), and placebo. Patients...

  12. Habitat Evaluation Procedures (HEP) Report; Upper Trimble Project, Technical Report 2004-2005.

    Energy Technology Data Exchange (ETDEWEB)

    Entz, Ray

    2005-02-01

    On July 13, 2004, the Habitat Evaluation Procedure (HEP) was used to determine baseline habitat suitability on the Upper Trimble property, an acquisition completed by the Kalispel Tribe of Indians in March 2004. Evaluation species and appropriate models include bald eagle, black-capped chickadee, Canada goose, mallard, muskrat, yellow warbler, and white-tailed deer. Habitat Suitability Index (HSI) values were visually estimated and agreed upon by all HEP team members. The Upper Trimble Project provides a total of 250.67 Habitat Units (HUs) for the species evaluated. Wet meadow provides 136.92 HUs for mallard, muskrat, and Canada goose. Mixed forest habitat provides 111.88 HUs for bald eagle, black-capped chickadee, mallard, and white-tailed deer. Scrub-shrub vegetation provides 1.87 HUs for yellow warbler, and white-tailed deer. The objective of using HEP at the Upper Trimble Project and other protected properties is to document the quality and quantity of available habitat for selected wildlife species. In this way, HEP provides information on the relative value of the same area at future points in time so that the effect of management activities on wildlife habitat can be quantified. When combined with other tools, the baseline HEP will be used to determine the most effective on-site management, restoration, and enhancement actions to increase habitat suitability for targeted species. The same process will be replicated every five years to quantitatively evaluate the effectiveness of management strategies in improving and maintaining habitat conditions while providing additional crediting to BPA for enhanced habitat values.

  13. Enhanced surveillance of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines in pregnancy in the Vaccine Adverse Event Reporting System (VAERS), 2011-2015.

    Science.gov (United States)

    Moro, Pedro L; Cragan, Janet; Tepper, Naomi; Zheteyeva, Yenlik; Museru, Oidda; Lewis, Paige; Broder, Karen

    2016-04-29

    In October 2011, the Advisory Committee on Immunization Practices (ACIP) issued updated recommendations that all pregnant women routinely receive a dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine. We characterized reports to the Vaccine Adverse Event Reporting System (VAERS) in pregnant women who received Tdap after this updated recommendation (2011-2015) and compared the pattern of adverse events (AEs) with the period before the updated recommendation (2005-2010). We searched the VAERS database for reports of AEs in pregnant women who received Tdap vaccine after the routine recommendation (11/01/2011-6/30/2015) and compared it to published data before the routine Tdap recommendation (01/01/2005-06/30/2010). We conducted clinical review of reports and available medical records. The clinical pattern of reports in the post-recommendation period was compared with the pattern before the routine Tdap recommendation. We found 392 reports of Tdap vaccination after the routine recommendation. One neonatal death but no maternal deaths were reported. No maternal or neonatal deaths were reported before the recommendation. We observed an increase in proportion of reports for stillbirths (1.5-2.8%) and injection site reactions/arm pain (4.5-11.9%) after the recommendation compared to the period before the routine recommendation for Tdap during pregnancy. We noted a decrease in reports of spontaneous abortion (16.7-1%). After the 2011 Tdap recommendation, in most reports, vaccination (79%) occurred during the third trimester compared to 4% before the 2011 Tdap recommendation. Twenty-six reports of repeat Tdap were received in VAERS; 13 did not report an AE. One medical facility accounted for 27% of all submitted reports. No new or unexpected vaccine AEs were noted among pregnant women who received Tdap after routine recommendations for maternal Tdap vaccination. Changes in reporting patterns would be expected, given the broader use of

  14. Annual report for 2004

    International Nuclear Information System (INIS)

    2005-01-01

    Article VI.J of the IAEA's Statute requires the Board of Governors to submit 'an annual report to the General Conference concerning the affairs of the Agency and any projects approved by the Agency'. This report covers the period 1 January to 31 December 2004. The Annual Report reviews the results of the Agency's programme according to the three pillars of technology, safety and verification. The main part of the report generally follows the programme structure as it applied in 2004. The introductory chapter, 'The Agency and the World in 2004', seeks to provide a thematic analysis, based on the three pillars, of the Agency's activities within the overall context of notable developments during the year. Information on specific issues can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review and Technical Cooperation Report. For the convenience of readers, these documents are available on the CD-ROM attached to this report. Additional information covering various aspects of the Agency's programme is also provided on the attached CD-ROM, and is also available on the Agency's iaea.org web site (http://www.iaea.org/Worldatom/Documents/Anrep/Anrep2004/). The Board of Governors oversees the ongoing operations of the Agency. It comprises 35 Member States and generally meets five times a year or more frequently if required for specific situations. Among its functions, the Board adopts the Agency's programme for the incoming biennium and makes recommendations on the Agency's budget to the General Conference. In 2004, the Board considered the Nuclear Technology Review 2004 and various activities related to nuclear science, technology and applications. This included authorizing the implementation of the Programme of Action for Cancer Therapy (PACT). In the area of safety and security, it considered the Nuclear Safety Review for the Year 2003 and related activities. It approved four Action Plans on various safety related activities and

  15. Annual report for 2004

    International Nuclear Information System (INIS)

    2005-01-01

    Article VI.J of the IAEA's Statute requires the Board of Governors to submit 'an annual report to the General Conference concerning the aff airs of the Agency and any projects approved by the Agency'. This report covers the period 1 January to 31 December 2004. The Annual Report reviews the results of the Agency's programme according to the three pillars of technology, safety and verification. The main part of the report generally follows the programme structure as it applied in 2004. The introductory chapter, 'The Agency and the World in 2004', seeks to provide a thematic analysis, based on the three pillars, of the Agency's activities within the overall context of notable developments during the year. Information on specific issues can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review and Technical Cooperation Report. For the convenience of readers, these documents are available on the CD-ROM attached to this report. Additional information covering various aspects of the Agency's programme is also provided on the attached CD-ROM, and is also available on the Agency's iaea.org web site (http://www.iaea.org/Worldatom/Documents/Anrep/Anrep2004/). The Board of Governors oversees the ongoing operations of the Agency. It comprises 35 Member States and generally meets five times a year or more frequently if required for specific situations. Among its functions, the Board adopts the Agency's programme for the incoming biennium and makes recommendations on the Agency's budget to the General Conference. In 2004, the Board considered the Nuclear Technology Review 2004 and various activities related to nuclear science, technology and applications. This included authorizing the implementation of the Programme of Action for Cancer Therapy (PACT). In the area of safety and security, it considered the Nuclear Safety Review for the Year 2003 and related activities. It approved four Action Plans on various safety related activities

  16. Habitat Evaluation Procedures (HEP) Report : Priest River, 2004-2005 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Entz, Ray

    2005-02-01

    On July 6, 2004, the Habitat Evaluation Procedure (HEP) was used to determine baseline habitat suitability on the Priest River property, an acquisition completed by the Kalispel Tribe of Indians in 2001. Evaluation species and appropriate models include bald eagle, black-capped chickadee, Canada goose, mallard, yellow warbler, and white-tailed deer. Habitat Suitability Index (HSI) values were visually estimated and agreed upon by all HEP team members. The Priest River Project provides a total of 105.41 Habitat Units (HUs) for the species evaluated. Conifer forest habitat provides 26.95 HUs for bald eagle, black-capped chickadee, and white-tailed deer. Grassland habitat provides 23.78 HUs for Canada goose and mallard. Scmb-shrub vegetation provides 54.68 HUs for mallard, yellow warbler, and white-tailed deer.

  17. Caracterização de genótipos de rotavírus em creches: era pré- e pós-vacinação contra o rotavírus Characterization of rotavirus strains from day care centers: pre- and post-rotavirus vaccine era

    Directory of Open Access Journals (Sweden)

    Simone G. Morillo

    2010-04-01

    Full Text Available OBJETIVOS: Em 2006, a vacina contra rotavírus foi incluída no Programa Nacional de Imunização. Este estudo teve como objetivo analisar os resultados da vigilância de genótipos de rotavírus em crianças OBJECTIVES: In 2006 the rotavirus vaccine was included in the Brazilian Immunization Program. The aim of this study was to report the results of a 5-year surveillance study of rotavirus strains in children < 5 years with acute gastroenteritis from day care centers in the state of São Paulo, Brazil. METHODS: This retrospective study was conducted with 30 day care centers from 2004 to 2008 with convenient surveillance fecal specimens, investigated by ELISA, SDS-PAGE, RT-PCR and gene sequencing to genotype characterization. RESULTS: Rotavirus infection was detected in 28.3% of samples (38/134. The most frequent genotypes detected were G9P[8] and G1P[8] in 2004; G1P[8] in 2005; GNTP[NT] in 2006; G2P[4] in 2007; and there were no cases in 2008. Mixed infections were not observed. Detection rate declined from 65.7% (23/35 in 2004 to 50% (9/18 in 2007. CONCLUSIONS: Genotype distribution varied according to collection year, accompanied by a reduction in detection rate. Use of rotavirus vaccine requires implementation of post-marketing surveillance to monitor rotavirus strain diversity and its efficacy against possible new emerging genotypes.

  18. WHO informal consultation on quality, safety and efficacy specifications for live attenuated rotavirus vaccines Mexico City, Mexico, 8-9 February 2005.

    Science.gov (United States)

    Wood, David

    2005-12-01

    Rotavirus vaccines are at an advanced stage of development but there are as yet no WHO recommendations on production and quality control to provide regulatory guidance. A meeting of experts was convened by WHO and PAHO/AMRO to review the scientific basis for production and quality control of rotavirus vaccines, and to discuss specific measures to assure the safety and efficacy of rotavirus vaccines. The meeting was attended by 25 experts from 14 countries, drawn from academia, public health, national regulatory authorities and vaccine producers. It was agreed that existing guidance for other live virus vaccines provides a very good basis for product characterization, especially for source materials and control of production. The basis for attenuation of current vaccines or vaccine candidates is not known but, at least for the vaccines based on the Jennerian approach of using animal (bovine) rotaviruses, is likely to be multigenic. The risk of intussusception in humans is influenced by genetic background and age. Recent analyzes of large vaccine safety trials found that certain strains of vaccine virus were not associated with intussusception, although in these trials the first dose of vaccine was not administered to children over 3 months of age. Since age is a risk factor for intussusception, this may suggest that early delivery of the first dose of vaccine is desirable. However, maternal antibodies may mitigate against early delivery of the first vaccine dose. Factors which could affect vaccine efficacy or safety include strain diversity, malnutrition, other enteric infections, parasitic infection or immune suppression. It was concluded that data from clinical trials conducted in one part of the world would not necessarily be predictive of vaccine efficacy in other places. It was agreed that in nonclinical evaluations there was a need to use oral dosing for toxicity studies and, because rotavirus is non-neurovirulent, that there was no need for an animal

  19. Threat-responsiveness and the decision to obtain free influenza vaccinations among the older adults in Taiwan.

    Science.gov (United States)

    Li, Ying-Chun; Liu, Chi-Mei

    2009-07-31

    Although older adults are encouraged by government agencies to receive influenza vaccinations, many do not obtain them. In Taiwan, where universal health care coverage has significantly reduced the barriers of access to care, the health care system has provided free influenza vaccinations for people 65 years or older since 2001. Nevertheless, the numbers of people who use this service are much fewer than expected. The aim of this study was to explore major factors that might affect the decision to receive influenza vaccinations among older adults in Taiwan. Using national representative health insurance medical claims from the National Health Insurance Research Database between 2002 and 2004, we investigated the role of threat-responsiveness, represented by prior vaccinations and prior physician visits for flu-like respiratory conditions, in the decisions of older adults to obtain vaccinations in Taiwan. Among the sample of 23,023 older adults, the overall yearly vaccination rates in this study were 38.6%, 44.3% and 39.3% for 2002, 2003, and 2004, respectively. Adjusting for covariates of individual and health care facility characteristics, the multivariate logistic regression revealed that older adults who had had prior vaccinations were ten times more likely to be vaccinated during the following influenza season than those who had not (OR=10.22, 95%CI: 9.82-10.64). The greater the frequency of prior physician visits for flu-like respiratory conditions, the greater the likelihood that one would decide to be vaccinated. Visits during prior interim (non-epidemic) season exerted a stronger positive influence than prior influenza season on this likelihood (OR=1.59, 95% CI: 1.46-1.73 vs. OR=1.11 95% CI: 1.01-1.22, respectively). Threat-responsiveness, or perceived risk, greatly influences influenza vaccination rates among the older adults in Taiwan. These findings can be used to help design public health campaigns to increase the influenza vaccination rate in this

  20. Evaluating the control of HPAIV H5N1 in Vietnam: virus transmission within infected flocks reported before and after vaccination

    Directory of Open Access Journals (Sweden)

    Pfeiffer Dirk U

    2010-06-01

    Full Text Available Abstract Background Currently, the highly pathogenic avian influenza virus (HPAIV of the subtype H5N1 is believed to have reached an endemic cycle in Vietnam. We used routine surveillance data on HPAIV H5N1 poultry outbreaks in Vietnam to estimate and compare the within-flock reproductive number of infection (R0 for periods before (second epidemic wave, 2004-5; depopulation-based disease control and during (fourth epidemic wave, beginning 2007; vaccination-based disease control vaccination. Results Our results show that infected premises (IPs in the initial (exponential phases of outbreak periods have the highest R0 estimates. The IPs reported during the outbreak period when depopulation-based disease control was implemented had higher R0 estimates than IPs reported during the outbreak period when vaccination-based disease control was used. In the latter period, in some flocks of a defined size and species composition, within-flock transmission estimates were not significantly below the threshold for transmission (R0 Conclusions Our results indicate that the current control policy based on depopulation plus vaccination has protected the majority of poultry flocks against infection. However, in some flocks the determinants associated with suboptimal protection need to be further investigated as these may explain the current pattern of infection in animal and human populations.

  1. Topical issues of vaccination and epidemiological surveillance over measles and rubella in Ukraine.

    OpenAIRE

    Daragan, G. M.; Krushinska, T. Yu.; Stepanskiy, D. O.; Demchyshyna, I. V.; Kolesnikova, I. P.

    2018-01-01

    The analysis of measles and rubella morbidity, the state of their vaccination in Ukraine was carried out. Despite decades of preventive vaccination, there is a 5-6 years’ cyclicity of measles epidemic process at present time. Measles morbidity increased 46.8 times in 2017 in comparison with 2016. Elevated rates of rubella epidemic morbidity were registered in 2004 and 2011. There was decrease of routine measles and rubella immunization coverage in the period from 2009 to 2016. Critically low ...

  2. Exploring the Limitations of Peripheral Blood Transcriptional Biomarkers in Predicting Influenza Vaccine Responsiveness

    Directory of Open Access Journals (Sweden)

    Luca Marchetti

    2017-01-01

    Full Text Available Systems biology has been recently applied to vaccinology to better understand immunological responses to the influenza vaccine. Particular attention has been paid to the identification of early signatures capable of predicting vaccine immunogenicity. Building from previous studies, we employed a recently established algorithm for signature-based clustering of expression profiles, SCUDO, to provide new insights into why blood-derived transcriptome biomarkers often fail to predict the seroresponse to the influenza virus vaccination. Specifically, preexisting immunity against one or more vaccine antigens, which was found to negatively affect the seroresponse, was identified as a confounding factor able to decouple early transcriptome from later antibody responses, resulting in the degradation of a biomarker predictive power. Finally, the broadly accepted definition of seroresponse to influenza virus vaccine, represented by the maximum response across the vaccine-targeted strains, was compared to a composite measure integrating the responses against all strains. This analysis revealed that composite measures provide a more accurate assessment of the seroresponse to multicomponent influenza vaccines.

  3. The Swedish Energy Market 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-10-01

    The Swedish Energy Market, 2005 is an annual publication that presents information and statistics on the network based energy markets in Sweden, i.e. the markets for electricity, natural gas and district heating. It also provides an overview of the issues that have arisen on these markets during the second half of 2004 and the first half of 2005. Considerable work is being carried out in the EU on creating a single market for electricity and natural gas. This publication therefore describes expansion of the Swedish market towards a Nordic and a European market. The publication normally includes a theme chapter, describing some event of particular interest for the Swedish energy market during the year. This year, the theme chapter is devoted to the Storm Gudrun, which struck the south of the country at the beginning of January, and its effects on electricity supply throughout the country. The chapter is based on the report submitted to the Government by the Energy Markets Inspectorate in the spring of 2005, and also includes a summary of the Inspectorate's proposals for measures to improve the security of electricity transmission. Energy in Sweden, which is another of the Swedish Energy Agency's annual publications, provides information and statistics on the development of the entire Swedish energy system.

  4. Savannah River Site Environmental Report for 2004

    International Nuclear Information System (INIS)

    Mamatey, Albert R.

    2005-01-01

    The Savannah River Site Environmental Report for 2004 (WSRC-TR-2005-00005) is prepared for the U.S. Department of Energy (DOE) according to requirements of DOE Order 231.1A, ''Environment, Safety and Health Reporting,'' and DOE Order 5400.5, ''Radiation Protection of the Public and Environment''. The report's purpose is to present summary environmental data that characterize site environmental management performance; confirm compliance with environmental standards and requirements; highlight significant programs and efforts; and assess the impact of SRS operations on the public and the environment

  5. Detection of Multiple Parallel Transmission Outbreak of Streptococcus suis Human Infection by Use of Genome Epidemiology, China, 2005.

    Science.gov (United States)

    Du, Pengcheng; Zheng, Han; Zhou, Jieping; Lan, Ruiting; Ye, Changyun; Jing, Huaiqi; Jin, Dong; Cui, Zhigang; Bai, Xuemei; Liang, Jianming; Liu, Jiantao; Xu, Lei; Zhang, Wen; Chen, Chen; Xu, Jianguo

    2017-02-01

    Streptococcus suis sequence type 7 emerged and caused 2 of the largest human infection outbreaks in China in 1998 and 2005. To determine the major risk factors and source of the infections, we analyzed whole genomes of 95 outbreak-associated isolates, identified 160 single nucleotide polymorphisms, and classified them into 6 clades. Molecular clock analysis revealed that clade 1 (responsible for the 1998 outbreak) emerged in October 1997. Clades 2-6 (responsible for the 2005 outbreak) emerged separately during February 2002-August 2004. A total of 41 lineages of S. suis emerged by the end of 2004 and rapidly expanded to 68 genome types through single base mutations when the outbreak occurred in June 2005. We identified 32 identical isolates and classified them into 8 groups, which were distributed in a large geographic area with no transmission link. These findings suggest that persons were infected in parallel in respective geographic sites.

  6. Cost-effectiveness of human papillomavirus vaccination in the United States.

    Science.gov (United States)

    Chesson, Harrell W; Ekwueme, Donatus U; Saraiya, Mona; Markowitz, Lauri E

    2008-02-01

    We describe a simplified model, based on the current economic and health effects of human papillomavirus (HPV), to estimate the cost-effectiveness of HPV vaccination of 12-year-old girls in the United States. Under base-case parameter values, the estimated cost per quality-adjusted life year gained by vaccination in the context of current cervical cancer screening practices in the United States ranged from $3,906 to $14,723 (2005 US dollars), depending on factors such as whether herd immunity effects were assumed; the types of HPV targeted by the vaccine; and whether the benefits of preventing anal, vaginal, vulvar, and oropharyngeal cancers were included. The results of our simplified model were consistent with published studies based on more complex models when key assumptions were similar. This consistency is reassuring because models of varying complexity will be essential tools for policy makers in the development of optimal HPV vaccination strategies.

  7. Electricity information 2006 - with 2005 data

    International Nuclear Information System (INIS)

    2006-01-01

    This publication provides a comprehensive review of historical and current market trends in the OECD electricity sector, including 2005 preliminary data. This reference document brings together in one volume essential statistics on electricity and heat. It therefore provides a strong foundation for policy and market analysis, which in turn can better inform the policy decision process toward selecting policy instruments best suited to meet domestic and international objectives. Part I of the publication provides a statistical overview of developments in the electricity and heat market. It includes information on production, installed capacity, input energy mix to electricity and heat production, input fuel prices, consumption, end-user electricity prices and electricity trades. Part I also includes some 2004 non-OECD country statistics on electricity and heat production, input fuel mix, supply and consumption, and electricity imports and exports. Part II provides, in tabular form, detailed and comprehensive statistical coverage of the power and heat industry developments for each of the 30 OECD member countries and for OECD and IEA regional aggregates. It provides comprehensive statistical details on overall energy consumption, economic indicators, electricity and heat production by energy form and plant type, electricity imports and exports, sectoral energy and electricity consumption as well as prices for electricity and electricity input fuels for each country and regional aggregate. This publication is one of a series of annual IEA statistical publications on major energy sources. The CD-ROM and on-line service contain detailed time series from 1960 to 2005 (end-use data only up to 2004)

  8. Mind the Gap: What explains the education-related inequality in missed opportunities for vaccination in sub-Saharan Africa? Compositional and structural characteristics.

    Science.gov (United States)

    Sambala, Evanson Z; Uthman, Olalekan A; Adamu, Abdu; Ndwandwe, Duduzile; Wiyeh, Alison B; Olukade, Tawa; Bishwajit, Ghose; Yaya, Sanni; Okwo-Bele, Jean-Marie; Wiysonge, Charles S

    2018-04-09

    Missed opportunities for vaccination (MOV) is an important barrier hindering full immunisation coverage among eligible children. Though factors responsible for MOV are well documented in literature, little attention has been paid to the role of inequalities. The aim of this study is to examine the association between structural or compositional factors and education inequalities in MOV. Blinder-Oaxaca decomposition technique was used to explain the factors contributing to the average gap in missed opportunities for vaccination between uneducated and educated mothers in sub-Saharan Africa using DHS survey data from 35 sub Saharan African countries collected between 2007 and 2016. The sample contained 69,657 children aged 12 to 23 months. We observed a wide variation and inter-country differences in the prevalence of missed opportunity for vaccination across populations and geographical locations. Our results show that the prevalence of MOV in Zimbabwe among uneducated and educated mothers was 9% and 21% respectively while in Gabon corresponding numbers were 85% and 89% respectively. In 15 countries, MOV was significantly prevalent among children born to uneducated mothers (pro-illiterate inequality) while in 5 countries MOV was significantly prevalent among educated mothers (pro-educated inequality). Our results suggest that education-related inequalities in missed opportunities for vaccination are explained by compositional and structural characteristics; and that neighbourhood socio-economic status was the most important contributor to education-related inequalities across countries followed by either the presence of under-five children, media access or household wealth index. The results showed that differential effects such as neighbourhood socio-economic status, presence of under-five children, media access and household wealth index, primarily explained education-related inequality in MOV. Interventions to reduce gaps in education-related inequality in MOV

  9. ECIU 2004-2005

    DEFF Research Database (Denmark)

    Hornemann, Birte C.; Nielsen, Kirsten Mølgaard; Bimberg, Christiane

    Programme. The aim of the Report is to review the internal decision-making processes of universities. This topic is one of the central fields of academic research into governance of universities. Some scientific papers and models already exist on such decision-making proc-esses and the second...

  10. Effect of Sulphur Fertilization on Grain Quality and Protein Composition of Durum Wheat (Triticum durum Desf.

    Directory of Open Access Journals (Sweden)

    Marianna Pompa

    2009-12-01

    Full Text Available The reduction of atmosphere emission of SO2 and the massive use of fertilizers high in nitrogen and phosphorus resulted in a decrease of the sulphur content in the soil. In durum wheat cultivation, sulphur supply plays a key role not only for plant growth, but also for grain quality. Sulphur is an essential macronutrient primarily used to synthesize methionine and cysteine and it is also involved in establishing protein structures by disulphide bonds. The aim of this study was to evaluate the effect of sulphur nutrition on grain quality and protein composition of durum wheat cultivars grown under water deficit conditions, typical of Mediterranean areas. To this purpose, in the 2003-2004 and 2004-2005 crop seasons a field trial was carried out by comparing two water regimes (irrigated and rainfed, two sulphur fertilizer levels and two durum wheat cultivars. Under our experimental conditions, an increase in protein and gluten content in the rainfed treatment and a positive effect of sulphur fertilization on quality parameters were observed. Few changes were observed in protein composition in response to sulphur fertilization.

  11. The European Activation File, EAF-2005

    International Nuclear Information System (INIS)

    Forrest, R.A.

    2005-01-01

    The current version of the European Activation File is EAF-2003. This contains various libraries of nuclear data required for activation calculations. An important component is the neutron-induced cross-section library. Plans to expose fusion components to high neutron fluxes include the IFMIF materials testing facility. This accelerator-based device will produce neutrons with a high-energy tail up to about 55 MeV. In order to carry out activation calculations on materials exposed to such neutrons it is necessary to extend the energy range of the cross-section library. Work on extending the energy range to 60 MeV is nearing completion. A test version (EAF-2004) was produced at the end of 2003 showing the feasibility of the chosen approach. This library required calculated data to extend the existing data from 20-60 MeV and to enlarge it with new classes of reactions with high thresholds. A summary of the new library EAF-2005, which is under development and is planned for distribution at the beginning of 2005, is given. The other files in EAF-2005 are briefly described; these cover cross-section uncertainty information and decay data. Both these have been extended beyond the current version to allow activation calculations at energies up to 60 MeV

  12. Explaining variation in the uptake of HPV vaccination in England

    Directory of Open Access Journals (Sweden)

    Whynes David K

    2011-03-01

    Full Text Available Abstract Background In England, two national programmes of HPV vaccination for girls have been instituted, a routine programme for 12- and 13-year-olds and a catch-up programme for 17- and 18-year-olds. Uptake rates across the country have been far from uniform, and this research sought to identify factors explaining the variation in uptake by locality. Methods An association between uptake, deprivation and ethnic background had been established in pilot research. The present analysis was conducted at an aggregate, Primary Care Trust (PCT, level for the first year of the programmes. Published measures of HPV vaccination uptake, material deprivation, ethnic composition of PCT populations, primary care quality, and uptake of cervical screening and of other childhood immunisations were collated. Strong evidence of collinearity amongst the explanatory variables required a factor analysis to be undertaken. This provided four independent factors, used thereafter in regression models to explain uptake by PCT. Results The factor analysis revealed that ethnic composition was associated with attitudes towards cervical screening and other childhood vaccinations, whilst material deprivation and quality of primary care were orthogonal. Ethnic composition, early childhood vaccination, cervical screening and primary care quality were found to be influential in predicting uptake in both the routine and the catch-up cohorts, although with a lower degree of confidence in the case of the last two independent variables. Lower primary care quality was significant in explaining a greater fall in vaccination uptake between the first two doses in the catch-up cohort. Greater deprivation was a significant explanatory factor for both uptake and the fall in uptake between doses for the catch-up cohort but not for uptake in the routine cohort. Conclusion These results for uptake of the first year of the national programme using aggregate data corroborate findings from

  13. Trends in colorectal cancer survival in northern Denmark: 1985-2004

    DEFF Research Database (Denmark)

    Iversen, Lene Hjerrild; Nørgaard, Mette; Jepsen, Peter

    2007-01-01

    OBJECTIVE: The prognosis for colorectal cancer (CRC) is less favourable in Denmark than in neighbouring countries. To improve cancer treatment in Denmark, a National Cancer Plan was proposed in 2000. We conducted this population-based study to monitor recent trends in CRC survival and mortality...... for age and gender. A total of 19,515 CRC patients were identified and linked with the Central Office of Civil Registration to ascertain survival through January 2005. Results: From 1985 to 2004, 1-year and 5-year survival improved both for patients with colon and rectal cancer. From 1995-1999 to 2000......-2004, overall 1-year survival of 65% for colon cancer did not improve, and some age groups experienced a decreasing 1-year survival probability. For rectal cancer, overall 1-year survival increased from 71% in 1995-1999 to 74% in 2000-2004. Using 1985-1989 as reference period, 30-day mortality did not decrease...

  14. Annual report of Naka Fusion Research Establishment from April 1, 2004 to March 31, 2005

    International Nuclear Information System (INIS)

    Yamamoto, Takumi; Sato, Masayasu; Kudo, Yusuke; Shu, Wataru; Yoshida, Hidetoshi

    2005-09-01

    This annual report provides an overview of research and development (R and D) activities at Naka Fusion Research Establishment during the period from 1 April, 2004 to 31 March, 2005, including those performed in collaboration with other research establishments of JAERI, research institutes, and universities. In the JT-60 research program, the pulse length of the tokamak discharge was extended successfully up to 65 s in FY 2003. In FY 2004, following the successful results, optimization of long pulse discharges was continued. The pulse length of the negative-ion based neutral beam injection system has reached up to 25 s with an injection power of 1 MW. In the electron cyclotron wave system, the pulse length has also extended up to 45 s with an RF power of 0.35 MW by using four gyrotrons in a series operation. Sustainment of higher normalized β of β N >2.3 for 22.3 s, or β N >2.5 for 15.5 s has been achieved by exploiting available plasma heating systems. This discharge exhibits not only the high β N , but also high confinement improvement with the H factor of H 89P =1.9-2.3 and high normalized fusion performance of G≡H 89P β N /q 95 2 =0.4-0.5 during the sustainment, where q 95 is a safety factor at the edge. G-0.4 corresponds to the fusion energy gain of Q=10 for the ITER standard scenario. The H-mode plasma with H 89P -1.4 has been maintained for about 30 s, although degradation of the performance was observed at the later half of the discharge. In the reversed shear plasmas, the operation regime was successfully extended. Demonstration of neoclassical tearing mode stabilization and improvement of plasma performance in the high beta region (β N - 3) has been performed using local current drive by the second harmonic electron cyclotron waves. In addition, a real-time control system of safety factor profile has been developed. The design of National Centralized Tokamak (NCT), which is the superconducting modification of JT-60, progressed both in physics and

  15. An assessment of the reliability of the Ontario electricity system : 18-month outlook from April 2004 to September 2005

    International Nuclear Information System (INIS)

    2004-01-01

    This report presents a resource assessment by the Independent Electricity Market Operator (IMO) for the 18-month period from April 2004 to September 2005. It is based on the IMO's forecast of electricity demand. The information was provided by power generators in Ontario. The outlook for the electricity system has improved due to the return to service of 3 nuclear units and the addition of more than 700 MW of generation. The return to service of the nuclear units has decreased Ontario's reliance on imports to help meet energy demand in the province. The shutdown of 1150 MW of coal-fired generation at Lakeview Thermal Generating Station in Mississauga emphasizes the importance of improving transmission and generation capacity in the Toronto area. This report also includes updated values for existing resource scenarios and planned resource scenarios. The reliability of Ontario's transmission system was also assessed along with the adequacy of the existing resource to meet the forecast demand. The existing installed generation resources include 5 nuclear stations generating 10,831 MW of electricity, 5 coal stations generating 7,564 MW of electricity, 22 oil and gas fired stations generating 4,364 MW of electricity, 61 hydroelectric stations generating 7,676 MW of electricity, and 2 other stations generating 66 MW of electricity. Although the existing resource scenario is better than in previous reports, imports will be required under extreme weather conditions to help meet electricity demand in Ontario during peak periods. 21 tabs., 10 figs

  16. Canadian natural gas winter 2005-06 outlook

    International Nuclear Information System (INIS)

    2005-11-01

    An outline of the Canadian natural gas commodity market was presented along with an outlook for Canadian natural gas supply and prices for the winter heating season of 2005-2006. In Canada, the level of natural gas production is much higher than domestic consumption. In 2004, Canadian natural gas production was 16.9 billion cubic feet per day (Bcf/d), while domestic consumption was much lower at 8.2 Bcf/d. The United States, whose natural gas consumption is higher than production, imported about 16 per cent of its natural gas supply from Canada and 3 per cent from other countries via liquefied natural gas imports. Canadian natural gas exports to the United States in 2004 was 8.7 Bcf/d, representing 51 per cent of Canada's production. In Canada, the most important natural gas commodity markets that determine natural gas commodity prices include the intra-Alberta market and the market at the Dawn, Ontario natural gas hub. A well connected pipeline infrastructure connects the natural gas commodity markets in Canada and the United States, allowing supply and demand fundamentals to be transferred across all markets. As such, the integrated natural gas markets in both countries influence the demand, supply and price of natural gas. Canadian natural gas production doubled from 7 to 16.6 Bcf/d between 1986 and 2001. However, in the past 3 years, production from western Canada has leveled out despite record high drilling activity. This can be attributed to declining conventional reserves and the need to find new natural gas in smaller and lower-quality reservoirs. The combination of steady demand growth with slow supply growth has resulted in high natural gas prices since the beginning of 2004. In particular, hurricane damage in August 2005 disrupted natural gas production in the Gulf of Mexico's offshore producing region, shutting-in nearly 9 Bcf/d at the height of damage. This paper summarized some of the key factors that influence natural gas market and prices, with

  17. Land area change analysis following hurricane impacts in Delacroix, Louisiana, 2004--2009

    Science.gov (United States)

    Palaseanu-Lovejoy, Monica; Kranenburg, Christine J.; Brock, John C.

    2012-01-01

    The purpose of this project is to provide improved estimates of Louisiana wetland land loss due to hurricane impacts between 2004 and 2009 based upon a change detection mapping analysis that incorporates pre- and post-landfall (Hurricanes Katrina, Rita, Gustav, and Ike) fractional water classification of a combination of high resolution (QuickBird, IKONOS and Geoeye-1) and medium resolution (Landsat) satellite imagery. This second dataset focuses on Hurricanes Katrina and Gustav, which made landfall on August 29, 2005, and September 1, 2008, respectively. The study area is an approximately 1208-square-kilometer region surrounding Delacroix, Louisiana, in the eastern Delta Plain. Overall, 77 percent of the area remained unchanged between 2004 and 2009, and over 11 percent of the area was changed permanently by Hurricane Katrina (including both land gain and loss). Less than 3 percent was affected, either temporarily or permanently, by Hurricane Gustav. A related dataset (SIM 3141) focused on Hurricane Rita, which made landfall on the Louisiana/Texas border on September 24, 2005, as a Category 3 hurricane.

  18. The evolving history of influenza viruses and influenza vaccines.

    Science.gov (United States)

    Hannoun, Claude

    2013-09-01

    The isolation of influenza virus 80 years ago in 1933 very quickly led to the development of the first generation of live-attenuated vaccines. The first inactivated influenza vaccine was monovalent (influenza A). In 1942, a bivalent vaccine was produced after the discovery of influenza B. It was later discovered that influenza viruses mutated leading to antigenic changes. Since 1973, the WHO has issued annual recommendations for the composition of the influenza vaccine based on results from surveillance systems that identify currently circulating strains. In 1978, the first trivalent vaccine included two influenza A strains and one influenza B strain. Currently, there are two influenza B lineages circulating; in the latest WHO recommendations, it is suggested that a second B strain could be added to give a quadrivalent vaccine. The history of influenza vaccine and the associated technology shows how the vaccine has evolved to match the evolution of influenza viruses.

  19. FY2005 AND FY2006 CORROSION SURVEILLANCE RESULTS FOR L BASIN

    International Nuclear Information System (INIS)

    Vormelker, P.; Cynthia Foreman, C.

    2008-01-01

    This report documents the results of the L-Basin Corrosion Surveillance Program for the fiscal years 2005 and 2006. The water quality and basin conditions for the coupon immersion period are compared to the corrosion evaluation results from detailed metallurgical analysis of the coupons. Test coupons were removed from the basin on two occasions, March 29, 2005 and May 23, 2006, examined and photographed. Selected coupons were metallurgically characterized to evaluate the extent of general corrosion and pitting. Crystallographic and energy dispersive spectroscopy analysis were performed on a typical specimen, as-removed from the basin, to characterize the surface debris. Marked changes were noted in both the 2005 and 2006 specimens compared to previous years corrosion results. A new pitting incidence has occurred on the faces of the aluminum coupons compared to localized pitting at crevice regions only on specimens withdrawn in 2003 and 2004. The pitting incidence is attributed to sand filter fines that entered the basin on July 27, 2004 from an inadvertent backflush of the new sand filter. Pitting rate results show a trend of slowing down over time which is consistent with aluminum pit kinetics. Average pit growth rates were equal to or lower in all 2006 aluminum coupons than those removed in 2005. A trend line shows that pitting corrosion rates on Al1100, 6061, and 6063 coupons are slowing down since pit depth measurements were initiated in 2003. No impact to stored spent fuel is expected from the debris. The storage configuration of the majority of L-Basin spent fuel, in bundles, should provide a measure of isolation from debris settling in the basin

  20. Lifestyle, body composition, and physical fitness changes in Hungarian school boys (1975-2005).

    Science.gov (United States)

    Photiou, A; Anning, J H; Mészáros, J; Vajda, I; Mészáros, Z; Sziva, A; Prókai, A; Ng, N

    2008-06-01

    General socioeconomic conditions as well as the physical environment have undergone remarkable changes in Hungary during the past 30 years. Unfortunately, these positive processes have resulted in a reduction of habitual physical activity along with unfavorable changes in dietary habits. Therefore, the purpose of the present study was to compare some selected morphological and functional parameters of 7-14-year-old Hungarian schoolboys living in the middle of the 1970s and at the beginning of the new millennium. It was hypothesized that there would be significant differences in morphological and functional characteristics of the Hungarian schoolboy populations, because they were assessed 30 years apart. Means of height, body mass, body mass index (BMI), the sum of five skinfold tests, percentage of body fat, and two running performance times (400 m and 1,200 m) of the boys (N = 3,672) studied in 1975 were compared to those of the boys (N = 3,758) in 2005. Data were analyzed using two-tailed independent samples t tests (p changes in body mass and height. In addition, boys in 2005 had significantly more subcutaneous fat compared to 1975. The running times for the two distances were significantly poorer at the time of the second investigation. The remarkable and unfavorable changes in body composition and cardiorespiratory performance were attributed to the continuously decreasing intensity of habitual physical exercise and a lifestyle that had become more sedentary (watching TV playing computer games, etc.). Radical interventions are necessary to reduce these risks associated with the high prevalence of cardiovascular disease in Hungary, and the challenge to resolve the problem requires combined efforts at the educational, societal, corporate, and governmental levels.

  1. A STUDY OF MEASLES VACCINATION COVERAGE BY LOT QUALITY ASSURANCE SAMPLING TECHNIQUE AND FACTORS RELATED TO NON-VACCINATION IN BELLARY DISTRICT

    Directory of Open Access Journals (Sweden)

    A Karinagannanavar

    2013-12-01

    Full Text Available Background: Measles is a leading cause of childhood morbidity and mortality accounting for nearly half the global burden of vaccine preventable deaths. In 2007, there were 197000 measles deaths globally nearly 540 deaths every day or 22 deaths per hour. According to NFHS-3 2005 – 06 total measles vaccination coverage in Karnataka was 72%. Objectives: 1 To find out measles vaccination coverage in Bellary District. 2 To know the reasons for non-vaccination. Material and Methods:   A Cross sectional study was conducted from May 2010 to April 2011 at areas covered by PHC/PHU of Bellary district by using Lot Quality Assurance Sampling (LQAS method. Total sample size was 1007(53X19. Bellary district has 47 primary health centers (PHC and 6 primary health units (PHU, all of which were studied in which each PHC/PHU is considered as a lot. The data was collected from parents of children aged 12-23 months using a pretested semi structured questionnaire. Results: Out of 53 PHC’s/PHU’s we accepted 41 (77.35% and vaccination coverage in these lots was considered as more than 85% and overall coverage in Bellary district was 69.41% and  53.62% had received Vitamin A supplementation. The reasons for non vaccination were lack of awareness, ignorance, ill health of the child, fear of side effects & lack of health services. Conclusion: Measles vaccination coverage was 69.41% and the reasons for non vaccination were lack of awareness, ignorance, ill health of the child, fear of side effects and lack of health services.

  2. A STUDY OF MEASLES VACCINATION COVERAGE BY LOT QUALITY ASSURANCE SAMPLING TECHNIQUE AND FACTORS RELATED TO NON-VACCINATION IN BELLARY DISTRICT

    Directory of Open Access Journals (Sweden)

    A Karinagannanavar

    2013-09-01

    Full Text Available Background: Measles is a leading cause of childhood morbidity and mortality accounting for nearly half the global burden of vaccine preventable deaths. In 2007, there were 197000 measles deaths globally nearly 540 deaths every day or 22 deaths per hour. According to NFHS-3 2005 – 06 total measles vaccination coverage in Karnataka was 72%. Objectives: 1 To find out measles vaccination coverage in Bellary District. 2 To know the reasons for non-vaccination. Material and Methods:   A Cross sectional study was conducted from May 2010 to April 2011 at areas covered by PHC/PHU of Bellary district by using Lot Quality Assurance Sampling (LQAS method. Total sample size was 1007(53X19. Bellary district has 47 primary health centers (PHC and 6 primary health units (PHU, all of which were studied in which each PHC/PHU is considered as a lot. The data was collected from parents of children aged 12-23 months using a pretested semi structured questionnaire. Results: Out of 53 PHC’s/PHU’s we accepted 41 (77.35% and vaccination coverage in these lots was considered as more than 85% and overall coverage in Bellary district was 69.41% and  53.62% had received Vitamin A supplementation. The reasons for non vaccination were lack of awareness, ignorance, ill health of the child, fear of side effects & lack of health services. Conclusion: Measles vaccination coverage was 69.41% and the reasons for non vaccination were lack of awareness, ignorance, ill health of the child, fear of side effects and lack of health services.

  3. Immunomodulatory and Physical Effects of Oil Composition in Vaccine Adjuvant Emulsions

    Science.gov (United States)

    Fox, Christopher B.; Baldwin, Susan L.; Duthie, Malcolm S.; Reed, Steven G.; Vedvick, Thomas S.

    2011-01-01

    Squalene-based oil-in-water emulsions have been used for years in some seasonal and pandemic influenza vaccines. However, concerns have been expressed regarding squalene source and potential biological activities. Little information is available regarding the immunomodulatory activity of squalene in comparison with other metabolizable oils in the context of oil-in-water emulsions formulated with vaccines. The present work describes the manufacture and physical characterization of emulsions composed of different classes of oils, including squalene, long chain triglycerides, a medium chain triglyceride, and a perfluorocarbon, all emulsified with egg phosphatidylcholine. Some differences were apparent among the non-squalene oils in terms of emulsion stability, including higher size polydispersity in the perfluorocarbon emulsion, more rapid visual instability at 60 °C for the long-chain triglyceride and perfluorocarbon emulsions, and an increased creaming rate in the medium-chain triglyceride emulsion at 60 °C as detected by laser scattering optical profiling. The biological activity of each of these emulsions was compared when formulated with either a recombinant malaria antigen or a split-virus inactivated influenza vaccine. Overall, vaccines containing the squalene emulsion elicited higher antibody titers and more abundant long-lived plasma cells than vaccines containing emulsions based on other oils. Since squalene-based emulsions show higher adjuvant potency compared to the other oils tested, non-squalene oils may be more suitable as carriers of amphiphilic or hydrophobic immunostimulatory molecules (such as TLR agonists) rather than as stand-alone adjuvants. PMID:21906648

  4. Report card on school snack food policies among the United States' largest school districts in 20042005: Room for improvement

    Directory of Open Access Journals (Sweden)

    Rivara Frederick P

    2006-01-01

    fundraising activities (47%. Most of the policies did not address more comprehensive approaches to the school nutrition environment, such as nutrition education (32% or advertising to students (26%, nor did they include guidelines on physical education (11%. In addition, few policies addressed monitoring (32% or consequences for non-compliance (11%. No policy restricted foods sold for after-school fundraising or required monitoring physical health indicators (e.g. BMI. Conclusion When compared to the Institute of Medicine's recommendations for schools' role in preventing obesity, none of the nutrition policies among each state's largest school district had addressed all the recommendations by 20042005. Nutritionists, nurses, pediatricians, parents, and others concerned about child health have an unprecedented opportunity to help shape and implement more comprehensive school district nutrition policies as part of the Congressional requirement for a "Wellness Policy" by 2006–2007.

  5. Hydrologic, Water-Quality, and Meteorological Data for the Cambridge, Massachusetts, Drinking-Water Source Area, Water Year 2005

    Science.gov (United States)

    Smith, Kirk P.

    2007-01-01

    station 01104455) were generally higher than the medians of the monthly mean specific conductances for the period of record. The annual mean specific conductance for Fresh Pond Reservoir increased from 514 microsiemens per centimeter (?S/cm) in the 2004 water year to 553 ?S/cm for the 2005 water year. Water samples were collected from four tributaries during base-flow and stormflow conditions in December 2004, and July, August, and September 2005 and analyzed for suspended sediment, 6 major dissolved ions, total nitrogen, total phosphorus, 8 total metals, 18 polyaromatic hydrocarbons (PAHs), 61 pesticides and metabolites, and Escherichia coli bacteria. Concentrations for most dissolved constituents in samples of stormwater were generally lower than the concentrations observed in samples collected during base flow; however, concentrations of total phosphorus, PAHs, suspended sediment, and some total recoverable metals were substantially greater in stormwater samples. Concentrations of dissolved chloride and total recoverable manganese in water samples collected during base-flow conditions from three tributaries exceeded the U.S. Environmental Protection Agency (USEPA) secondary drinking water standards of 250 and 0.05 milligrams per liter (mg/L), respectively. Concentrations of total recoverable manganese exceeded the secondary drinking water standard in samples of stormwater from each tributary. Concentrations of total recoverable iron in water samples exceeded the (USEPA) secondary drinking water standard of 0.3 mg/L periodically in water samples collected at (USEPA) stations 01104415, 01104455, and 01104475, and consistently in all water samples collected at USGS station 01104433. Concentrations of Escherichia coli bacteria in water samples collected during base flow ranged from 4 to 1,400 colony-forming units per 100 milliliters (col/100mL). Concentrations of Escherichia coli bacteria in composite samples of stormwater ranged between 1,700 to 43,000 c

  6. Economische consequenties invoering CTT-norm zoute baggerspecie voor Nederlandse havens: evaluatie CTT norm 2004-2005

    NARCIS (Netherlands)

    Linderhof, V.G.M.; Hess, S.; Kruseman, G.; Hattum, van B.; Bruinsma, F.; Jonkeren, O.; Ubbels, E.

    2006-01-01

    In juni 2004 werd een nieuw toetsingskader, de Chemie-Toxiciteit-Toets (CTT), voor zoute baggerspecie geïntroduceerd. De CTT vervangt de Uniforme Gehalte Toets (UGT). De belangrijkste wijzigingen zijn de expliciete norm voor Tributyltin (TBT) en signaleringswaarden voor een drietal bio-assays. Op

  7. EXPERIMENTAL LIPOSOMAL VIRAL VACCINE SAFETY

    Directory of Open Access Journals (Sweden)

    Romanova OA

    2016-12-01

    Full Text Available Introduction. With the transport links development there is rather important issue respiratory viral infections spread, especially influenza. The only method controlling influenza is vaccination. Search and development effective and safe vaccines is important. Material and methods. In base SO "Mechnikov Institute Microbiology and Immunology National Ukrainian Academy Medical Sciences" in the scientific theme "Developing new approaches to creating viral vaccines and study specific activity depending of type and degree component`s modification" was created several experimental influenza vaccine with subsequent component`s modification for selecting the most optimal pattern of safety and immunogenicity. In assessing the influenza vaccine safety is using a few criteria, including, reactivity, as measured by the frequency of local and systemic adverse (negative effects, which due to its introduction, and for lipid content drugs, ability to influence oxidation processes. At present study phase was determined: a systemic reaction and local reaction of delayed-type hypersensitivity (foot pad swelling assay;b lipids and proteins peroxidation processes after administration officinal and experimental vaccines (content protein’s carbonyl groups, lipid’s hydroperoxides, activity of glutathione-peroxidase.Study objects were trivalent seasonal influenza vaccine, "Vaxigrip" (Sanofi Pasteur, S.A., France, "Inflexal V" (Biotech Ltd. Berne, Switzerland and experimental vaccine samples. Highest immunogenicity vaccines had undergone improvements and modifications using adjuvant systems and acylation influenza proteins. Liposomes 2 – the experimental influenza vaccine with a liposome negative charge and antigenic composition like split vaccines "Vaksihryp". Liposomes 2.1 - the adjuvantexperimental influenza vaccine with modifications liposomal components (etoniy and chlorophyllipt molecules embedded in liposomal membrane. Liposomes 2.2 - the adjuvant

  8. Subatomic Physics and Cosmology Laboratory - LPSC Grenoble. Activity report 2004-2005

    International Nuclear Information System (INIS)

    Chretien-Duhamel, G.; Baylac, M.; Billebaud, A.; Cholat, C.; Collot, J.; Comparat, V.; Derome, L.; Lamy, T.; Lucotte, A.; Ollivier, N.; Real, J.S.; Regairaz, W.; Richard, J.M.; Silvestre-Brac, B.; Stutz, A.; Tur, C.; Favro, C.

    2006-01-01

    seek answers to the existence of dark matter and dark energy in the universe. The locations of the experiments are very diverse: ground-based, underground-based or even satellite-based. LPSC also studies artificially created short-lived particles (created by accelerators which our laboratory helps to design) or cosmic particles that were produced at different epochs of the history of the universe. These activities require the development of sophisticated, state-of-the-art instrumentation. A close collaboration between physicists, engineers and technicians is required to achieve the required performance. In addition, a strong theoretical research activity supports the experiments during the preparatory stages and during the data analysis. This report presents the activities of the laboratory during the years 2004-2005: 1 - Forewords; 2 - Quarks, leptons and FUNDAMENTAL INTERACTIONS (DΦ, ATLAS, Ultra-cold Neutrons - UCN); 3 - Cosmology and cosmic radiations (AMS-CREAM, Archeops-Planck, MIMAC-He3, EUSO-ULTRA); 4 - Hadrons and nuclei (nucleons and light nuclei structure, GRAAL, Reactor physics); 5 - pluri-disciplinary programs (physics-medicine interface, ETOILE, Research centre on plasmas-materials-nano-structures - CRPMN); 6 - Theory; 7 - Accelerators and ion sources; 8 - Technical and administrative Services: detectors and Instrumentation, Mechanics, Electronics, Data acquisition and Computers departments, General services, Communication, Technology Valorisation and transfer, Administration; 9 - Communication; 10 - Human resources, Health and safety; 11 - Staff and organigram; 12 - Training and teaching; 13 - Publications; 14 - Redaction committee

  9. IMPACTS OF THE 2005 FOOT AND MOUTH DISEASE OUTBREAK ON BRAZILIAN BEEF EXPORTS

    Directory of Open Access Journals (Sweden)

    Diana Cortes Carvalho Garcia

    2015-10-01

    Full Text Available Foot and Mouth Disease (FMD can lead to sanitary barriers to international trade and involves high investments for control and great losses in the event of an outbreak. This study investigated the impacts caused by FMD on the exports of fresh beef from Brazil after the 2005 outbreak and the observance of the regionalization principle of the Agreement on the Application of Sanitary and Phytosanitary Measures (SPS by countries member of the WTO that were listed as the top 10 beef importing countries in 2004. The FMD outbreak that began in 2005 did not limit the increase in exports of fresh beef from Brazil, but impacted negatively on exports from Mato Grosso do Sul and Paraná States. The disease did not impact exports to the United States, Japan or Mexico, since these markets were closed to Brazil. Saudi Arabia, Russia and Iran were not members of the WTO in October 2005 and therefore had no obligation to respect the principle of regionalization, though Russia respected it. Among the other major importers of 2004, the Netherlands, Egypt, Italy, United Kingdom, France, Germany and Spain respected the principle of regionalization of the SPS Agreement. Chile did not respect the principle and the occurrence of the disease closed the market to Brazilian fresh beef.

  10. Como pagar to educacion, 2004-2005 (Funding Your Education, 2004-2005).

    Science.gov (United States)

    Office of Federal Student Aid (ED), Washington, DC.

    This publication, written in Spanish, describes financial aid programs of the U.S. Department of Education and advises students about paying for college. It outlines things a student should ask about college and how to obtain financial aid, whether grants, work-study, or loans. Chapters provide information on: (1) "Education after High School";…

  11. [Quality assessment of dermatology in the G-DRG system 2004].

    Science.gov (United States)

    Fürstenberg, T; Hensen, P; Rompel, R; Roeder, N

    2004-11-01

    Since January 2004, all German hospitals have been obliged to operate with a new hospital funding system based on DRGs. For the DRG system to serve as a fair basis for reimbursement requires that the dermatologic services be adequately covered in the classification system. The German Dermatologic Society (DDG) in cooperation with the DRG-Research Group of the University Hospital Muenster carried out a DRG evaluation study. Based on these results, suggestions for the adjustment of the G-DRG system were proposed by the DDG in the G-DRG adaptation round for 2004. Based on data of the DRG evaluation project (14,555 dermatological cases from 19 hospitals) the homogeneity in the G-DRG system 2004 was examined and compared with the quality of depiction in the G-DRG version 1.0. The correlation between expenditure and case mix index in the hospitals improved in the G-DRG system 2004. Most proposals submitted by the German Dermatologic Society for the adaptation into the G-DRG system 2004 were accepted. Some fundamental problems such as reimbursement of high cost drugs and special services, as well as the reimbursement of high and low outliers, were only marginally addressed. The G-DRG system 2004 will need to be continuously adapted in the field of dermatology. Based on this work, the German Dermatologic Society has made suggestions to be adapted in the G-DRG system 2005 and submitted them to the German DRG Institute.

  12. Analysis of vaccination campaign effectiveness and population immunity to support and sustain polio elimination in Nigeria.

    Science.gov (United States)

    Upfill-Brown, Alexander M; Voorman, Arend; Chabot-Couture, Guillaume; Shuaib, Faisal; Lyons, Hil M

    2016-03-30

    The world is closer than ever to a polio-free Africa. In this end-stage, it is important to ensure high levels of population immunity to prevent polio outbreaks. Here, we introduce a new method of assessing vaccination campaign effectiveness and estimating immunity at the district-level. We demonstrate how this approach can be used to plan the vaccination campaigns prospectively to better manage population immunity in Northern Nigeria. Using Nigerian acute flaccid paralysis surveillance data from 2004-2014, we developed a Bayesian hierarchical model of campaign effectiveness and compared it to lot-quality assurance sampling data. We then used reconstructed sero-specific population immunity based on campaign history and compared district estimates of immunity to the occurrence of confirmed poliovirus cases. Estimated campaign effectiveness has improved across northern Nigeria since 2004, with Kano state experiencing an increase of 40 % (95 % CI, 26-54 %) in effectiveness from 2013 to 2014. Immunity to type 1 poliovirus has increased steadily. On the other hand, type 2 immunity was low and variable until the recent use of trivalent oral polio vaccine. We find that immunity estimates are related to the occurrence of both wild and vaccine-derived poliovirus cases and that campaign effectiveness correlates with direct measurements using lot-quality assurance sampling. Future campaign schedules highlight the trade-offs involved with using different vaccine types. The model in this study provides a novel method for assessing vaccination campaign performance and epidemiologically-relevant estimates of population immunity. Small-area estimates of campaign effectiveness can then be used to evaluate prospective campaign plans. This modeling approach could be applied to other countries as well as other vaccine preventable diseases.

  13. The impact of declining vaccination coverage on measles control: a ...

    African Journals Online (AJOL)

    Introduction: Efforts at immunizing children against measles was intensified in Nigeria with nation-wide measles vaccination campaigns in 2005 - 2006, 2008 and 2011 targeting children between 9 and 59 months. However, there were measles outbreaks in 2010 and 2011in Abia state Nigeria. This study seeks to find out if ...

  14. Pneumococcal serotypes and serogroups causing invasive disease in Pakistan, 2005-2013.

    Directory of Open Access Journals (Sweden)

    Sadia Shakoor

    Full Text Available While pneumococcal conjugate vaccines have been implemented in most countries worldwide, use in Asia has lagged in part because of a lack of data on the amount of disease that is vaccine preventable in the region. We describe pneumococcal serotypes elicited from 111 episodes of invasive pneumococcal disease (IPD from 2005 to 2013 among children and adults in Pakistan. Seventy-three percent (n = 81 of 111 IPD episodes were cases of meningitis (n = 76 in children 0-15 years and n = 5 among adults. Serotypes were determined by target amplification of DNA extracted from pneumococcal isolates (n = 52 or CSF specimens (n = 59. Serogroup 18 was the most common serogroup causing meningitis in children <5 years, accounting for 21% of cases (n = 13. The 10-valent pneumococcal conjugate vaccine (PCV 10 or PCV10- related serotypes were found in 61% (n = 47 of childhood (age 0-15 years meningitis episodes. PCV-13 increased this coverage to 63% (one additional serotype 19A; n = 48. Our data indicate that use of PCVs would prevent a large proportion of serious pneumococcal disease.

  15. A systematic review of health economic evaluations of vaccines in Brazil.

    Science.gov (United States)

    Sartori, Ana Marli Christovam; Rozman, Luciana Martins; Decimoni, Tassia Cristina; Leandro, Roseli; Novaes, Hillegonda Maria Dutilh; de Soárez, Patrícia Coelho

    2017-06-03

    In Brazil, since 2005, the Ministry of Health requires Health Economic Evaluation (HEE) of vaccines for introduction into the National Immunization Program. To describe and analyze the full HEE on vaccines conducted in Brazil from 1980 to 2013. Systematic review of the literature. We searched multiple databases. Two researchers independently selected the studies and extracted the data. The methodological quality of individual studies was evaluated using CHEERS items. Twenty studies were reviewed. The most evaluated vaccines were pneumococcal (25%) and HPV (15%). The most used types of HEE were cost-effectiveness analysis (45%) and cost-utility analysis (20%). The research question and compared strategies were stated in all 20 studies and the target population was clear in 95%. Nevertheless, many studies did not inform the perspective of analysis or data sources. HEE of vaccines in Brazil has increased since 2008. However, the studies still have methodological deficiencies.

  16. From Epidemic Meningitis Vaccines for Africa to the Meningitis Vaccine Project.

    Science.gov (United States)

    Aguado, M Teresa; Jodar, Luis; Granoff, Dan; Rabinovich, Regina; Ceccarini, Costante; Perkin, Gordon W

    2015-11-15

    Polysaccharide vaccines had been used to control African meningitis epidemics for >30 years but with little or modest success, largely because of logistical problems in the implementation of reactive vaccination campaigns that are begun after epidemics are under way. After the major group A meningococcal meningitis epidemics in 1996-1997 (250,000 cases and 25,000 deaths), African ministers of health declared the prevention of meningitis a high priority and asked the World Health Organization (WHO) for help in developing better immunization strategies to eliminate meningitis epidemics in Africa. WHO accepted the challenge and created a project called Epidemic Meningitis Vaccines for Africa (EVA) that served as an organizational framework for external consultants, PATH, the US Centers for Disease Control and Prevention (CDC), and the Bill & Melinda Gates Foundation (BMGF). Consultations were initiated with major vaccine manufacturers. EVA commissioned a costing study/business plan for the development of new group A or A/C conjugate vaccines and explored the feasibility of developing these products as a public-private partnership. Representatives from African countries were consulted. They confirmed that the development of conjugate vaccines was a priority and provided information on preferred product characteristics. In parallel, a strategy for successful introduction was also anticipated and discussed. The expert consultations recommended that a group A meningococcal conjugate vaccine be developed and introduced into the African meningitis belt. The results of the costing study indicated that the "cost of goods" to develop a group A - containing conjugate vaccine in the United States would be in the range of US$0.35-$1.35 per dose, depending on composition (A vs A/C), number of doses/vials, and presentation. Following an invitation from BMGF, a proposal was submitted in the spring of 2001. In June 2001, BMGF awarded a grant of US$70 million to create the Meningitis

  17. New Brunswick System Operator 2005 annual report

    International Nuclear Information System (INIS)

    2005-01-01

    New Brunswick's electricity generating mix includes thermal, hydro and nuclear power. Facts about New Brunswick's electricity market were presented with reference to transmission lines; number of interconnecting operators; interconnection capacity; installed generation capacity; generation capacity mix; peak demand for 2004-2005; total energy transactions over a 6 month period and value of electricity over that 6 month period. The independently governed New Brunswick System Operator (NBSO) began operations in 2004 with a mandate to introduce competitive integrated electricity supply to municipal utilities and large industrial customers in order to ensure a reliable and adequate supply of electricity to the Maritime area. The NBSO's first task to launch the transition from monopoly supply to a competitive market is in the beginning stages, but progress has been made in terms of market rules, new computerized systems, and consultations with the Market Advisory Committee who review potential changes to the market rules and tariffs. tabs., figs

  18. O processo de planejamento e periodização do treino em futebol nos clubes da principal liga portuguesa profissional de futebol na época 2004/2005 The training planning and periodization processes in professional football Portuguese league 2004/2005

    Directory of Open Access Journals (Sweden)

    Pedro Santos

    2011-09-01

    Full Text Available O planejamento e a periodização são fases cruciais diretamente implicadas na eficácia, consistência e qualidade do jogo das equipes. Foram objetivos deste estudo investigar: 1 a implementação da dinâmica da "carga" e sua relação com os períodos; 2 a importância atribuída às componentes da "carga" e recuperação; 3 a prescrição da intensidade; 4 as componentes do rendimento consideradas no planejamento, sua importância hierárquica e, forma de trabalho; 5 o aspecto considerado central no planejamento; 6 o tipo de planejamento utilizado na preparação da equipe; e 7 a utilização da modelação no processo de treino. O universo estudado foi constituído pelas 18 equipes do principal escalão de Futebol, na época 2004/2005. Foi aplicado um inquérito por questionário validado por sete especialistas. Representando cada um dos clubes em estudo, responderam ao questionário 16 treinadores principais e dois adjuntos, por remessa do respetivo treinador principal. Os resultados sugerem que embora pareça não ser a corrente de treino dominante, o paradigma da dimensão física do treino aparece ainda bastante vincado. Alguns dos pressupostos associados à conceção tradicional do treino permanecem presentes. Parece ser costume operacionalizar um planejamento com base na dimensão tática. Apesar desta ser a "guia" do processo, e "arrastar" a dimensão física, nem sempre tal acontece. Embora surjam situações em que ainda se promove a separação das dimensões do rendimento, a referência passa por trabalhá-las, sempre que possível, simultaneamente. A modelação do jogo é uma tendência na maioria dos clubes. Nem todos os treinadores agem de acordo com as suas convicções expressas.Planning and periodization are assumed to be crucial phases directly implied in the efficiency, consistency and game quality of the teams. The aim of this work is to investigate: 1 the implementation of the "load`s" dynamics and its relation to

  19. Checking, Sharing, Clicking and Linking: Changing patterns of news use between 2004 and 2014

    NARCIS (Netherlands)

    Costera Meijer, I.; Groot Kormelink, T.

    2014-01-01

    This paper challenges the generally taken-for-granted automatic link between media platforms, media technology and news user practices. It explores what has changed in people’s news consumption by comparing patterns in news use between 20042005 and 2011–2014. While new, social and mobile media

  20. Clinical characteristics of Haemophilus influenzae meningitis in Denmark in the post-vaccination era

    DEFF Research Database (Denmark)

    Pedersen, T.I.; Howitz, M.; Andersen, Christian Østergaard

    2010-01-01

    P>The introduction of Haemophilus influenzae type b (Hib) vaccine into the Danish childhood vaccination programme in 1993 may have influenced the epidemiology of H. influenzae meningitis (i.e. increasing frequency of other non-vaccine types; presentation in other age groups). Based on nationwide...... registration, clinical information and laboratory findings were collected from all 65 confirmed cases of H. influenzae meningitis during the period 1994-2005. Twenty-nine patients (45%) were 24 years old [median 62 years (range 25...... infected with Hib, two cases (13%) were identified as true vaccine failures. Six patients (9%) died; one premature infant infected with serotype f and five adults (age 83-96 years) with non-typeable H. influenzae. Hearing loss was reported in 16% of the surviving children and in 10% of the surviving adults...

  1. Savannah River Site Environmental Report for 2004

    Energy Technology Data Exchange (ETDEWEB)

    Mamatey, Albert R.

    2005-06-07

    The Savannah River Site Environmental Report for 2004 (WSRC-TR-2005-00005) is prepared for the U.S. Department of Energy (DOE) according to requirements of DOE Order 231.1A, ''Environment, Safety and Health Reporting,'' and DOE Order 5400.5, ''Radiation Protection of the Public and Environment''. The report's purpose is to present summary environmental data that characterize site environmental management performance; confirm compliance with environmental standards and requirements; highlight significant programs and efforts; and assess the impact of SRS operations on the public and the environment.

  2. Threat-responsiveness and the decision to obtain free influenza vaccinations among the older adults in Taiwan

    Directory of Open Access Journals (Sweden)

    Liu Chi-Mei

    2009-07-01

    Full Text Available Abstract Background Although older adults are encouraged by government agencies to receive influenza vaccinations, many do not obtain them. In Taiwan, where universal health care coverage has significantly reduced the barriers of access to care, the health care system has provided free influenza vaccinations for people 65 years or older since 2001. Nevertheless, the numbers of people who use this service are much fewer than expected. The aim of this study was to explore major factors that might affect the decision to receive influenza vaccinations among older adults in Taiwan. Methods Using national representative health insurance medical claims from the National Health Insurance Research Database between 2002 and 2004, we investigated the role of threat-responsiveness, represented by prior vaccinations and prior physician visits for flu-like respiratory conditions, in the decisions of older adults to obtain vaccinations in Taiwan. Results Among the sample of 23,023 older adults, the overall yearly vaccination rates in this study were 38.6%, 44.3% and 39.3% for 2002, 2003, and 2004, respectively. Adjusting for covariates of individual and health care facility characteristics, the multivariate logistic regression revealed that older adults who had had prior vaccinations were ten times more likely to be vaccinated during the following influenza season than those who had not (OR = 10.22, 95%CI: 9.82–10.64. The greater the frequency of prior physician visits for flu-like respiratory conditions, the greater the likelihood that one would decide to be vaccinated. Visits during prior interim (non-epidemic season exerted a stronger positive influence than prior influenza season on this likelihood (OR = 1.59, 95% CI: 1.46–1.73 vs. OR = 1.11 95% CI: 1.01–1.22, respectively. Conclusion Threat-responsiveness, or perceived risk, greatly influences influenza vaccination rates among the older adults in Taiwan. These findings can be used to help design

  3. Areva 2005 annual report; Areva rapport annuel 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This annual report contains information on AREVA's objectives, prospects and strategies, particularly in Chapters 4 and 7, as well as contains information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the annual report and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction; 3 - General information on the company and share capital: Information on AREVA, Information on share capital and voting rights, Investment certificate trading, Dividends, Organizational chart of the AREVA group, Equity interests, Shareholders' agreements; 4 - Information on company operations, 5 - New developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, AREVA group energy businesses, Front End Division, Reactors and Services Division, Back End Division, Transmission and Distribution Division, Major Contracts, The Group's principal sites, AREVA's customers and suppliers, Human resources, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development, intellectual property and brand name programs, Risk and insurance; 6 - Assets - Financial position - financial performance: Analysis of and comments on the Group's financial position and performance, Human Resources report 2005, Environmental report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA Financial statements 2005, Notes to the corporate financial statements; 7 - Corporate governance: Composition and functioning of administrative bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual General Meeting of Shareholders of May 2, 2006; 8 - Recent developments and outlook: Events subsequent to year-end closing for 2005, Outlook.

  4. Areva 2005 annual report; Areva rapport annuel 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This annual report contains information on AREVA's objectives, prospects and strategies, particularly in Chapters 4 and 7, as well as contains information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the annual report and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction; 3 - General information on the company and share capital: Information on AREVA, Information on share capital and voting rights, Investment certificate trading, Dividends, Organizational chart of the AREVA group, Equity interests, Shareholders' agreements; 4 - Information on company operations, 5 - New developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, AREVA group energy businesses, Front End Division, Reactors and Services Division, Back End Division, Transmission and Distribution Division, Major Contracts, The Group's principal sites, AREVA's customers and suppliers, Human resources, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development, intellectual property and brand name programs, Risk and insurance; 6 - Assets - Financial position - financial performance: Analysis of and comments on the Group's financial position and performance, Human Resources report 2005, Environmental report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA Financial statements 2005, Notes to the corporate financial statements; 7 - Corporate governance: Composition and functioning of administrative bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual General Meeting of Shareholders of May 2, 2006; 8 - Recent developments and outlook: Events subsequent to year-end closing for 2005, Outlook.

  5. High-yield production of a stable Vero cell-based vaccine candidate against the highly pathogenic avian influenza virus H5N1

    International Nuclear Information System (INIS)

    Zhou, Fangye; Zhou, Jian; Ma, Lei; Song, Shaohui; Zhang, Xinwen; Li, Weidong; Jiang, Shude; Wang, Yue; Liao, Guoyang

    2012-01-01

    Highlights: ► Vero cell-based HPAI H5N1 vaccine with stable high yield. ► Stable high yield derived from the YNVa H3N2 backbone. ► H5N1/YNVa has a similar safety and immunogenicity to H5N1delta. -- Abstract: Highly pathogenic avian influenza (HPAI) viruses pose a global pandemic threat, for which rapid large-scale vaccine production technology is critical for prevention and control. Because chickens are highly susceptible to HPAI viruses, the supply of chicken embryos for vaccine production might be depleted during a virus outbreak. Therefore, developing HPAI virus vaccines using other technologies is critical. Meeting vaccine demand using the Vero cell-based fermentation process has been hindered by low stability and yield. In this study, a Vero cell-based HPAI H5N1 vaccine candidate (H5N1/YNVa) with stable high yield was achieved by reassortment of the Vero-adapted (Va) high growth A/Yunnan/1/2005(H3N2) (YNVa) virus with the A/Anhui/1/2005(H5N1) attenuated influenza vaccine strain (H5N1delta) using the 6/2 method. The reassorted H5N1/YNVa vaccine maintained a high hemagglutination (HA) titer of 1024. Furthermore, H5N1/YNVa displayed low pathogenicity and uniform immunogenicity compared to that of the parent virus.

  6. Lack of effect of a booster dose of influenza vaccine in hemodialysis patients.

    Science.gov (United States)

    Tanzi, Elisabetta; Amendola, Antonella; Pariani, Elena; Zappa, Alessandra; Colzani, Daniela; Logias, Franco; Perego, Angelo; Zanetti, Alessandro R

    2007-08-01

    To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms of percentage of response and of mean-fold increase of hemagglutination inhibiting (HI) antibody titer, but not in terms of seroprotection rates (HI antibody titers > or =1:40). The second vaccine administration did not result in additional increase in seroprotection rate or in geometric mean titers. Protective immune response against the epidemic A/H3N2 Fujian-like strain, antigenically distant from that included in the vaccine (A/Panama/2007/99) was observed in 94.7% of vaccinees protected against the A/H3N2 vaccine strain 1 month after immunization. No adverse reactions were reported during follow-up. The study findings suggest that immune response to influenza vaccination may be suboptimal in hemodialysis patients and that the administration of an additional second dose of vaccine does not improve the humoral response.

  7. Dutch Energy Investment Allowance (EIA) 2004; Energie Investeringsaftrek 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The purpose of the title incentive (EIA) is to stimulate energy conservation and the use of renewable energy in the Dutch industry and businesses. This brochure provides information on the changes with respect to the year 2003, how the EIA can be applied, and examples of energy investments (the so-called Energy List) [Dutch] Doel van de regeling Energie-investeringsaftrek (EIA) is energiebesparing en de inzet van duurzame energie door het Nederlandse bedrijfsleven te stimuleren. In deel 1 van deze brochure vindt u de wijzigingen ten opzichte van het jaar 2003. In deel 2 treft u een uitleg aan over de werking van de EIA. In deel 3 leest u hoe u gebruik kunt maken van deze regeling. In deel 4 is een overzicht opgenomen met omschrijvingen en voorbeelden van energie-investeringen, de zogenoemde Energielijst. In deel 5 zitten bestelbonnen waarmee u brochures voor de diverse fiscale regelingen kunt aanvragen. Deel 6 is een formulier waarmee u een voorstel kunt doen om de voor u liggende Energielijst 2004 voor 2005 aan te vullen of te wijzigen.

  8. Control of bovine ringworm by vaccination in Norway.

    Science.gov (United States)

    Lund, Arve; Bratberg, Anna Marie; Næss, Bjørn; Gudding, Roar

    2014-03-15

    Bovine ringworm caused by Trichophyton verrucosum is a notifiable disease in Norway. New infected herds are reported to the Norwegian Food Safety Authority. To limit spread of the disease, restrictions are imposed on holdings including access to common pastures and sale of live animals. Bovine ringworm has been endemic in the Norwegian dairy population for decades. Since 1980 a vaccine (Bovilis Ringvac LTF-130, Merck Animal Health) has been available. The vaccine contains an attenuated strain of T. verrucosum and stimulates humoral and cellular immune responses conferring protection. Efficacy and safety of the vaccine have been evaluated in experimental and field studies. Vaccination campaigns in densely populated counties have contributed to a substantial decrease in number of ringworm outbreaks. The annual incidence of new infected herds decreased from 1.7% in 1980 to 0.043% in 2004. Few herds remained with restrictions and a "mopping up" project was established to offer assistance specifically to these holdings. A milestone was achieved in 2009; no new herds with cases of clinical ringworm caused by T. verrucosum were reported to the authorities. By end of 2012, there are only two herds with restrictions. Vaccination during the last 30 years has been a key control measure in the effort to prevent disease outbreaks and eradicate bovine ringworm in Norway. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. ERADIKASI POLIO DAN IPV (INACTIVATED POLIO VACCINE

    Directory of Open Access Journals (Sweden)

    Gendrowahyuhono Gendrowahyuhono

    2012-09-01

    Full Text Available In the year 1988, World Health Organization (WHO claims that polio viruses should be eradicated after year 2000. However, until year 2010 the world have not been free from polio viruses circulation. So many effort had been achieved and it is estimated that the world will be free from polio virus after the year 2013. Control of poliomyelitis in Indonesia has been commenced since 1982 with routine immunization of polio program and the National Immunization Days (NID has been commenced since 1995,1996,2005 and 2006. When the world is free from polio virus, WHO suggests several alternative effort to maintain the world free from polio viruses : I stop the OPV (Oral Polio Vaccine and no polio immunization, 2 stop OPV and stock pile mOPV (monovalent OPV, 3 use OPV and IPV (Inactivated Polio Vaccine in a certain times, 4 use IPV only in a certain times. IPV has been used routinely in develop countries but has not been used in the developing countries. Several studies in development countries has been conducted, but had not been done in the developing countries. Indonesia collaboration with WHO has conducted the study of IPV in Yogyakarta Province since year 2002 until year 2010. The overall aim of the study is to compile the necessary data that will inform global and national decision-making regarding future polio immunization policies for the OPV cessation era. The data generated from the study will be particularly important to make decisions regarding optimal IPV use in developing tropical countries. It is unlikely that this data can be assembled through other means than through this study. The tentative result of the study shows that OPV immunization coverage in the year 2004 is 99% in four district and 93 % in the Yogyakarta city. Environment surveillance shows that there are 65.7% polio virus detected from 137 sewage samples pre IPV swich, and 4.8% polio virus detected from 83 sewage samples post IPV swich. Survey polio antibody serologis shows

  10. Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo

    Directory of Open Access Journals (Sweden)

    Emanuele Amodio

    2010-09-01

    Full Text Available

    Background: Annual flu vaccination of healthcare workers (HCWs is recommended worldwide as the best way to prevent influenza and to avoid its transmission. However, in several European Countries, vaccination rate among HCWs is still less than 25%. The aim of this study was to determine the HCW vaccination coverage during a three year period in a large University Hospital, identifying socio demographic and occupational variables involved in the decision to accept influenza vaccination. Moreover, for the 2007-2008 season, we also assessed the effectiveness of influenza vaccination in reducing influenza-related absenteeism.

    Methods: During three consecutive influenza seasons (from 2005-2006 to 2007-2008, a cross-sectional study was carried out on all HCWs employed in the “Azienda Ospedaliera Universitaria Policlinico” (AOUP of Palermo (Italy. Socio-demographic and occupational data of HCWs were collected from administrative hospital personnel records and included gender, age, birthplace, residence, profession and the workplace unit. In addition, during the 2007-2008 season, a retrospective study was conducted to evaluate absence from work due to influenza–like illness (ILI in vaccinated versus unvaccinated personnel.

    Results: A total of 7,848 HCW-years were observed and 881 vaccines were administered during the study period. Vaccination rate declined from 14.7% in 2005-2006 to 8.2% in 2007-2008 (Chi-square for trend=53.6, p<0.001. Coverage was generally higher among older and male HCWs whereas nurses and workers in surgical areas had lower vaccination rates. In the 2007-2008 season, absenteeism due to ILI in the vaccinated group was significantly less common than unvaccinated HCWs (3.3% vs 7.1%; p=0.04.

    Conclusions: Our experience encourages flu vaccination of HCWs and accentuates the importance of annual influenza vaccination programs

  11. Role of the private sector in vaccination service delivery in India: evidence from private-sector vaccine sales data, 2009-12.

    Science.gov (United States)

    Sharma, Abhishek; Kaplan, Warren A; Chokshi, Maulik; Zodpey, Sanjay P

    2016-09-01

    India's Universal Immunization Programme (UIP) provides basic vaccines free-of-cost in the public sector, yet national vaccination coverage is poor. The Government of India has urged an expanded role for the private sector to help achieve universal immunization coverage. We conducted a state-by-state analysis of the role of the private sector in vaccinating Indian children against each of the six primary childhood diseases covered under India's UIP. We analyzed IMS Health data on Indian private-sector vaccine sales, 2011 Indian Census data and national household surveys (DHS/NFHS 2005-06 and UNICEF CES 2009) to estimate the percentage of vaccinated children among the 2009-12 birth cohort who received a given vaccine in the private sector in 16 Indian states. We also analyzed the estimated private-sector vaccine shares as function of state-specific socio-economic status. Overall in 16 states, the private sector contributed 4.7% towards tuberculosis (Bacillus Calmette-Guérin (BCG)), 3.5% towards measles, 2.3% towards diphtheria-pertussis-tetanus (DPT3) and 7.6% towards polio (OPV3) overall (both public and private sectors) vaccination coverage. Certain low income states (Uttar Pradesh, Rajasthan, Madhya Pradesh, Orissa, Assam and Bihar) have low private as well as public sector vaccination coverage. The private sector's role has been limited primarily to the high income states as opposed to these low income states where the majority of Indian children live. Urban areas with good access to the private sector and the ability to pay increases the Indian population's willingness to access private-sector vaccination services. In India, the public sector offers vaccination services to the majority of the population but the private sector should not be neglected as it could potentially improve overall vaccination coverage. The government could train and incentivize a wider range of private-sector health professionals to help deliver the vaccines, especially in the low

  12. Financial requirements of immunisation programmes in developing countries: a 2004-2014 perspective.

    Science.gov (United States)

    Peny, Jean-Michel; Gleizes, Olivier; Covilard, Jean-Pierre

    2005-08-31

    Vaccines are a key contributor to public health, especially in developing countries. Despite numerous demonstrations of the cost-effectiveness of immunisation, vaccines spending accounted for only 1.7% of the total pharmaceutical market in 2002, when UNICEF estimated that 34 million children were not reached by routine immunisation, most of them in developing countries. Several international organizations or initiatives, like the Global Alliance for Vaccines and Immunisation (GAVI), have defined a long-term goal of universal immunisation in developing countries. There is an urgent need to estimate the financial resources required to meet this goal. The objective of this study was to anticipate the funding needs for childhood immunisation in developing countries over the 2004-2014 period. The study scope includes all the 75 countries eligible for support from GAVI, and covers existing vaccines that are considered as a priority for GAVI (DTP (diphtheria, tetanus, pertussis), hepatitis B, Haemophilus influenzae type b (as a stand alone presentation or in combination with DTP) and yellow fever) as well as future vaccines (meningitis A and C, rotavirus, human papilloma virus (HPV), malaria, Streptococcus pneumoniae and tuberculosis) likely to be available within the 10-year period. We developed a methodology to estimate the number of doses required, based on disease prevalence and incidence, target populations, introduction dates of new vaccines, coverage dynamics and dosing regimen. The introduction price and price evolution of vaccines over time were modelled, taking into account the type of vaccine, the expected return on investment from vaccine manufacturers and the competitive landscape. Non-vaccine costs (capital costs and non-vaccine recurrent costs) were estimated based on the number of people immunised and number of doses dispensed, using available case studies as a reference. According to the optimal scenario that would consider the provision of all vaccines

  13. Chlamydia positivity in New Orleans public high schools, 1996-2005: implications for clinical and public health practices.

    Science.gov (United States)

    Nsuami, M Jacques; Nsa, Musheni; Brennan, Christine; Cammarata, Catherine L; Martin, David H; Taylor, Stephanie N

    2013-01-01

    To describe the trends in chlamydia positivity among New Orleans high school students tested in a schoolwide screening between 1996 and 2005, and to determine factors associated with chlamydia positivity among students during the 10-year period. Between school years 1995-1996 and 2004-2005, students in New Orleans public high schools were tested for chlamydia using nucleic acid amplification tests (NAAT) in urine specimens (LCx assay until 1999-2000; BD assay from 2000-2001 to 2004-2005). For each year, we calculated chlamydia positivity by dividing the number of students testing positive by the total number of students tested. Data were analyzed separately by gender. Logistic regressions were performed to determine independent predictors of chlamydia positivity during the 10-year period. Between 1996 and 2005, the average chlamydia positivity was 7.0% (95% confidence interval 6.6-7.4) in boys and 13.1% (95% confidence interval 12.6-13.7) in girls (P New Orleans school-age adolescent population. Any benefit of screening on individuals tested was likely to be mitigated by participants' uninterrupted social interactions with the dynamic forces that sustain the sexual transmission of chlamydia in the population. Copyright © 2013 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  14. Monitoring county-level chlamydia incidence in Texas, 20042005: application of empirical Bayesian smoothing and Exploratory Spatial Data Analysis (ESDA methods

    Directory of Open Access Journals (Sweden)

    Owens Chantelle J

    2009-02-01

    Full Text Available Abstract Background Chlamydia continues to be the most prevalent disease in the United States. Effective spatial monitoring of chlamydia incidence is important for successful implementation of control and prevention programs. The objective of this study is to apply Bayesian smoothing and exploratory spatial data analysis (ESDA methods to monitor Texas county-level chlamydia incidence rates by examining spatiotemporal patterns. We used county-level data on chlamydia incidence (for all ages, gender and races from the National Electronic Telecommunications System for Surveillance (NETSS for 2004 and 2005. Results Bayesian-smoothed chlamydia incidence rates were spatially dependent both in levels and in relative changes. Erath county had significantly (p 300 cases per 100,000 residents than its contiguous neighbors (195 or less in both years. Gaines county experienced the highest relative increase in smoothed rates (173% – 139 to 379. The relative change in smoothed chlamydia rates in Newton county was significantly (p Conclusion Bayesian smoothing and ESDA methods can assist programs in using chlamydia surveillance data to identify outliers, as well as relevant changes in chlamydia incidence in specific geographic units. Secondly, it may also indirectly help in assessing existing differences and changes in chlamydia surveillance systems over time.

  15. Comparison of the characteristics of fire and non-fire households in the 2004-2005 survey of fire department-attended and unattended fires.

    Science.gov (United States)

    Greene, Michael A

    2012-06-01

    Comparison of characteristics of fire with non-fire households to determine factors differentially associated with fire households (fire risk factors). National household telephone survey in 2004-2005 by the US Consumer Product Safety Commission with 916 fire households and a comparison sample of 2161 non-fire households. There were an estimated 7.4 million fires (96.6% not reported to fire departments) with 130,000 injuries. Bivariate analysis and multivariate logistic regression analyses to assess differences in household characteristics. Significant factors associated with fire households were renting vs. owning (OR 1.988 pfire households with non-cooking fires (OR 1.383 p=0.0011). Single family houses were associated with non-fire households in the bivariate analysis but not in the multivariate analyses. Renting, household members under 18 years old and smokers are risk factors for unattended fires, similar to the literature for fatal and injury fires. Differences included household members over 65 years old (associated with non-fire households), college/postgraduate education (associated with fire households) and lack of significance of income. Preventing cooking fires (64% of survey incidents), smoking prevention efforts and fire prevention education for families with young children have the potential for reducing unattended fires and injuries.

  16. EDF - 2005 Consolidated Annual Results - Analysts' Presentation. Consolidated financial statements at December 31, 2005

    International Nuclear Information System (INIS)

    2006-01-01

    As the world's biggest electricity generator, the EDF Group covers every sector of expertise, from generation to trading and transmission grids. EDF builds on the expertise of its people, its R and D and engineering skills, its experience as a leading industry operator and the attentive support of its customers to deliver competitive solutions that successfully reconcile economic growth with climate protection. This document presents the 2005 annual results and Consolidated financial statements of the Group at 31 December 2005: Consolidated income statements, consolidated balance sheets, consolidated cash flow statements, variation in consolidated equity, notes (group accounting policies, impact of first-time application of IFRs, transition to standards IAS 32 and 39 concerning financial instruments, summary of accounting and valuation methods, public distribution concessions in France, significant events and transactions of 2005, impact of the law of august 9, 2004 on comparability, changes in the scope of consolidation, segment reporting, sales, fuel and energy purchases, other external expenses, contractual obligations and commitments entered into in the course of business, personnel expenses, other operating income and expenses, other income and expenses, financial result, income taxes, basic earnings per share and diluted earnings per share, goodwill, other intangible assets, property, plant and equipment, investments in companies accounted for under the equity method, financial assets, inventories, including work-in-process, trade receivables, other receivables, cash and cash equivalents, available-for-sale assets and liabilities, equity, provisions, special concession liabilities, current and non-current financial liabilities, derivatives, other liabilities, related parties, greenhouse gas emission quotas, environment, subsequent events, scope of consolidation

  17. Spatial and environmental connectivity analysis in a cholera vaccine trial.

    Science.gov (United States)

    Emch, Michael; Ali, Mohammad; Root, Elisabeth D; Yunus, Mohammad

    2009-02-01

    This paper develops theory and methods for vaccine trials that utilize spatial and environmental information. Satellite imagery is used to identify whether households are connected to one another via water bodies in a study area in rural Bangladesh. Then relationships between neighborhood-level cholera vaccine coverage and placebo incidence and neighborhood-level spatial variables are measured. The study hypothesis is that unvaccinated people who are environmentally connected to people who have been vaccinated will be at lower risk compared to unvaccinated people who are environmentally connected to people who have not been vaccinated. We use four datasets including: a cholera vaccine trial database, a longitudinal demographic database of the rural population from which the vaccine trial participants were selected, a household-level geographic information system (GIS) database of the same study area, and high resolution Quickbird satellite imagery. An environmental connectivity metric was constructed by integrating the satellite imagery with the vaccine and demographic databases linked with GIS. The results show that there is a relationship between neighborhood rates of cholera vaccination and placebo incidence. Thus, people are indirectly protected when more people in their environmentally connected neighborhood are vaccinated. This result is similar to our previous work that used a simpler Euclidean distance neighborhood to measure neighborhood vaccine coverage [Ali, M., Emch, M., von Seidlein, L., Yunus, M., Sack, D. A., Holmgren, J., et al. (2005). Herd immunity conferred by killed oral cholera vaccines in Bangladesh. Lancet, 366(9479), 44-49]. Our new method of measuring environmental connectivity is more precise since it takes into account the transmission mode of cholera and therefore this study validates our assertion that the oral cholera vaccine provides indirect protection in addition to direct protection.

  18. Polymer multilayer tattooing for enhanced DNA vaccination

    Science.gov (United States)

    Demuth, Peter C.; Min, Younjin; Huang, Bonnie; Kramer, Joshua A.; Miller, Andrew D.; Barouch, Dan H.; Hammond, Paula T.; Irvine, Darrell J.

    2013-04-01

    DNA vaccines have many potential benefits but have failed to generate robust immune responses in humans. Recently, methods such as in vivo electroporation have demonstrated improved performance, but an optimal strategy for safe, reproducible, and pain-free DNA vaccination remains elusive. Here we report an approach for rapid implantation of vaccine-loaded polymer films carrying DNA, immune-stimulatory RNA, and biodegradable polycations into the immune-cell-rich epidermis, using microneedles coated with releasable polyelectrolyte multilayers. Films transferred into the skin following brief microneedle application promoted local transfection and controlled the persistence of DNA and adjuvants in the skin from days to weeks, with kinetics determined by the film composition. These ‘multilayer tattoo’ DNA vaccines induced immune responses against a model HIV antigen comparable to electroporation in mice, enhanced memory T-cell generation, and elicited 140-fold higher gene expression in non-human primate skin than intradermal DNA injection, indicating the potential of this strategy for enhancing DNA vaccination.

  19. Polymer multilayer tattooing for enhanced DNA vaccination

    Science.gov (United States)

    DeMuth, Peter C.; Min, Younjin; Huang, Bonnie; Kramer, Joshua A.; Miller, Andrew D.; Barouch, Dan H.; Hammond, Paula T.; Irvine, Darrell J.

    2014-01-01

    DNA vaccines have many potential benefits but have failed to generate robust immune responses in humans. Recently, methods such as in vivo electroporation have demonstrated improved performance, but an optimal strategy for safe, reproducible, and pain-free DNA vaccination remains elusive. Here we report an approach for rapid implantation of vaccine-loaded polymer films carrying DNA, immune-stimulatory RNA, and biodegradable polycations into the immune-cell-rich epidermis, using microneedles coated with releasable polyelectrolyte multilayers. Films transferred into the skin following brief microneedle application promoted local transfection and controlled the persistence of DNA and adjuvants in the skin from days to weeks, with kinetics determined by the film composition. These “multilayer tattoo” DNA vaccines induced immune responses against a model HIV antigen comparable to electroporation in mice, enhanced memory T-cell generation, and elicited 140-fold higher gene expression in non-human primate skin than intradermal DNA injection, indicating the potential of this strategy for enhancing DNA vaccination. PMID:23353628

  20. Seroepidemiological study of human cysticercosis with blood samples collected on filter paper, in Lages, State of Santa Catarina, Brazil, 2004-2005 Estudo soroepidemiológico da cisticercose humana com amostras de sangue total coletado em papel filtro, em Lages, Estado de Santa Catarina, 2004-2005

    Directory of Open Access Journals (Sweden)

    Maria Márcia Imenes Ishida

    2011-06-01

    Full Text Available INTRODUCTION: Human serofrequency of antibodies against Taenia solium antigens was determined and risk factors for cysticercosis transmission were identified. METHODS: Individuals (n=878 from periurban and rural locations of Lages, SC, were interviewed to gather demographic, sanitary and health information. Interviews and blood sample collections by finger prick on Whatman filter paper were performed from August 2004 to May 2005. Observation determined that 850 samples were suitable for analysis and were tested by ELISA using vesicular fluid of Taenia crassiceps heterologous antigen. To ensure the reliability of the results, 77 samples of the dried blood were matched with sera. The reactive samples were submitted to a serum confirmatory immunoblot (IB test using purified Taenia crassiceps glycoproteins. RESULTS: The ELISA results for the dried blood and serum samples were statistically consistent. ELISA was positive in 186 (21.9% out of 850 individuals. A group of 213 individuals were asked to collect vein blood for IB (186 with positive result in ELISA and 27 with inappropriate whole blood samples and 130 attended the request. The IB was positive in 29 (3.4% out of 850 individuals. A significant correlation (p = 0.0364 was determined among individuals who tested positive in the IB assay who practiced both pig rearing and kitchen gardening. CONCLUSIONS: ELISA with dried blood eluted from filter paper was suitable for cysticercosis population surveys. In Lages, human infection was associated with pig rearing and kitchen gardening. The prevalence index was compatible with other Latin American endemic areas.INTRODUÇÃO: O primeiro levantamento sobre cisticercose humana e identificação dos fatores de risco associados à transmissão, foram realizados em Lages, SC. MÉTODOS: Oitocentos e setenta e sete voluntários de regiões periurbana e rural foram entrevistados e forneceram informações demográficas e condições sanitárias e de sa

  1. INIS Progress and Activity Report 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-03-15

    Highlights of INIS Activities 2004: INIS, the International Nuclear Information System, is an established nuclear information resource operated by the IAEA on behalf of its Members. Its primary mission is to foster open information exchange for the scientific benefit of its Members. In 2004, Botswana joined INIS, bringing the total number of participating members to 130, including 111 countries and 19 international organizations. Bibliographic Database In the year 2004, a total of 106,886 records were added to the INIS Bibliographic Database. This represents an increase of 21,7% over last year's total of 87,822 and constitutes, it is worth mentioning, the best annual result ever achieved by INIS during its entire history. There are now 2,541,950 records in the INIS database. Such a successful outcome has been made possible by the continued cooperation of Member States in preparing their own national input, the voluntary contributions of many Member States, and the efforts of the INIS Secretariat in covering a backlog of scientific journals. Voluntary contributions included 6,564 bibliographic records prepared by INIS Member States1 (an increase of 33 % compared to 2003) and 43,041 records prepared by the INIS Secretariat (an increase of 64 % compared to 2003). The gap in the coverage of core journals, identified for the period starting with 1999, is almost being filled. The backlog of journals from the Institute of Physics Publishing (IOPP) and Elsevier Science is now fully covered, and the acquisition and processing of their records for current issues has now become routine. From the American Institute of Physics (AIP), 10,779 records remained in the backlog at the end of 2004 and will be covered in the first months of 2005, and once this is done the acquisition and processing of AIP records for current issues will also become routine.

  2. INIS Progress and Activity Report 2004

    International Nuclear Information System (INIS)

    2005-03-01

    Highlights of INIS Activities 2004: INIS, the International Nuclear Information System, is an established nuclear information resource operated by the IAEA on behalf of its Members. Its primary mission is to foster open information exchange for the scientific benefit of its Members. In 2004, Botswana joined INIS, bringing the total number of participating members to 130, including 111 countries and 19 international organizations. Bibliographic Database In the year 2004, a total of 106,886 records were added to the INIS Bibliographic Database. This represents an increase of 21,7% over last year’s total of 87,822 and constitutes, it is worth mentioning, the best annual result ever achieved by INIS during its entire history. There are now 2,541,950 records in the INIS database. Such a successful outcome has been made possible by the continued cooperation of Member States in preparing their own national input, the voluntary contributions of many Member States, and the efforts of the INIS Secretariat in covering a backlog of scientific journals. Voluntary contributions included 6,564 bibliographic records prepared by INIS Member States1 (an increase of 33 % compared to 2003) and 43,041 records prepared by the INIS Secretariat (an increase of 64 % compared to 2003). The gap in the coverage of core journals, identified for the period starting with 1999, is almost being filled. The backlog of journals from the Institute of Physics Publishing (IOPP) and Elsevier Science is now fully covered, and the acquisition and processing of their records for current issues has now become routine. From the American Institute of Physics (AIP), 10,779 records remained in the backlog at the end of 2004 and will be covered in the first months of 2005, and once this is done the acquisition and processing of AIP records for current issues will also become routine

  3. Red Oak Research and Demonstration Area in Phelps Township, North Bay, Ontario-2004 to 2005

    Science.gov (United States)

    Dave Deugo; Andrée Morneault; Dianne Othmer; Megan Smith; Al Stinson; Murray Woods; Ian Kovacs; Ian Aho; Bill Parker; Rob Baker; Marinus Verwey; Guylaine Thauvette; Don Willis; Jeff Dech

    2006-01-01

    In July 2004, a large stand of red oak (Quercus rubra) was harvested in Phelps Township, North Bay District, North Bay, Ontario using the uniform shelterwood system. Most of the stand was harvested to retain 40 percent crown closure, while a very small portion was harvested to retain 70 percent crown closure. During tree marking, an active Northern...

  4. Factores de riesgo asociados a hábitos bucales deformantes en niños de 5 a 11 años. Policlínica “René Vallejo Ortiz”: Manzanillo. 2004 - 2005

    OpenAIRE

    Reyes Romagosa, Daniel Enrique; Rosales Rosales, Katiuska; Roselló Salcedo, Olga; García Arias, Dasha María

    2007-01-01

    RESUMEN Se  realizó un estudio de tipo caso control  de niños afectados por hábitos bucales  deformantes de la  Policlínica III “Rene Vallejo Ortiz”  de  Manzanillo en el periodo comprendido entre abril  del 2004 y abril  del 2005, con el objetivo de identificar los factores de riesgo asociados a esos hábitos bucales deformantes. Del total de niños de 5 a 11 años del área se seleccionaron 180 niños, 60 niños con hábitos bucales deformantes  que se examinaron en consulta y se les realizó una e...

  5. Calendar year 2004 annual site environmental report:Sandia National Laboratories, Albuquerque, New Mexico.

    Energy Technology Data Exchange (ETDEWEB)

    Montoya, Amber L.; Goering, Teresa Lynn; Wagner, Katrina; Koss, Susan I.; Salinas, Stephanie A.

    2005-09-01

    Sandia National Laboratories, New Mexico (SNL/NM) is a government-owned, contractor-operated facility owned by the U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA) and managed by the Sandia Site Office (SSO), Albuquerque, New Mexico. Sandia Corporation, a wholly-owned subsidiary of Lockheed Martin Corporation, operates SNL/NM. This annual report summarizes data and the compliance status of Sandia Corporation's environmental protection and monitoring programs through December 31, 2004. Major environmental programs include air quality, water quality, groundwater protection, terrestrial surveillance, waste management, pollution prevention (P2), environmental restoration (ER), oil and chemical spill prevention, and the National Environmental Policy Act (NEPA). Environmental monitoring and surveillance programs are required by DOE Order 450.1, Environmental Protection Program (DOE 2005) and DOE Order 231.1A, Environment, Safety, and Health Reporting (DOE 2004a). (DOE 2004a).

  6. Socioeconomic Determinants of the Utilization of Antenatal Care and Child Vaccination in India.

    Science.gov (United States)

    Zuhair, Mohd; Roy, Ram Babu

    2017-11-01

    Antenatal care and child vaccination services are adopted worldwide to reduce the risk of child mortality, maternal mortality, and burden of infectious diseases. This article examines the effect of socioeconomic factors on the utilization of antenatal care and child vaccination services in India. The generalized linear model has been used along with the Indian National Family Health Survey data for the period 2005-2006. The analysis shows that the health insurance plan has a significant effect on the use of antenatal care but not in the child vaccination. Furthermore, there is inequality in the utilization of antenatal care as well as child vaccination services and it is positively related to the wealth. The study suggests that there is a need to improve the socioeconomic status of the financially weaker section of the society for improving the use of child and maternal care services.

  7. Overview and charge - Snowmass Workshop 2005

    International Nuclear Information System (INIS)

    Berger, E. L.

    2006-01-01

    This contribution to the published Proceedings records the opening talk I presented on the first morning of the 2005 International Linear Collider Workshop in Snowmass, CO, August 14 - 27, 2005. It includes a summary of the motivation for the workshop, the scientific goals and charges for the working groups, the initial plans of the accelerator, detector, and physics groups, and the activities of the communication, education, and outreach group. This document also describes organizational aspects of the meeting, particularly the scientific committee structure, the self-organization of the working groups, the composition of the indispensable secretariat and computer support teams, and the sources of funding support. The report serves as an introduction to the proceedings whose individual papers and summary documents must be consulted for an appreciation of the accomplishments and progress made at Snowmass in 2005 toward the realization of an International Linear Collider

  8. Changes in late-winter snowpack depth, water equivalent, and density in Maine, 1926-2004

    Science.gov (United States)

    Hodgkins, Glenn A.; Dudley, Robert W.

    2006-03-01

    Twenty-three snow-course sites in and near Maine, USA, with records spanning at least 50 years through to 2004 were tested for changes over time in snowpack depth, water equivalent, and density in March and April. Of the 23 sites, 18 had a significant decrease (Mann-Kendall test, p 1950s and 1960s, and densities peaked in the most recent decade. Previous studies in western North America also found a water-equivalent peak in the third quarter of the 20th century. Published in 2006 by John Wiley & Sons, Ltd.Received: 14 June 2005; Accepted: 7 October 2005

  9. The CO2 emissions bond to the energy combustion in the world in 2005

    International Nuclear Information System (INIS)

    2007-01-01

    The CO 2 emissions for different countries are compared for the years 1990 2004 and 2005, from statistical data of the AIE. The emissions are calculated in relation of the gross domestic product and the population. A special attention and a sectoral analysis is provided for France. (A.L.B.)

  10. Trends in boarding of admitted patients in US Emergency Departments 2003-2005.

    Science.gov (United States)

    Carr, Brendan G; Hollander, Judd E; Baxt, William G; Datner, Elizabeth M; Pines, Jesse M

    2010-10-01

    Boarding of admitted patients in the Emergency Department (ED) is common and is associated with poor patient outcomes. We sought to estimate the magnitude of and trends for ED boarding in the US. We used the 2003-2005 National Hospital Ambulatory Medical Care Survey to estimate the time patients spent boarding in EDs in the US. We used fixed and imputed times required to evaluate, treat, and decide to admit each patient using the number of medications and diagnostic tests received. We calculated the absolute and relative patient-care hours spent boarding in US EDs over the 3-year period. Total patient-hours spent in US EDs increased from 209 million to 217 million between 2003 and 2005. Overall admission rates decreased between 2003 and 2005 (13.9% in 2003, 12.3% in 2005), whereas intensive care unit admission rates increased (1.3% in 2003, 2.0% in 2005). Mean ED length of stay decreased (5.4 h in 2003, 4.6 h in 2005). The proportion of patient-hours accounted for by ED boarding decreased over the study period (11.3-17.1% in 2003, 5.9-15.3% in 2004, and 2.8-12.0% 2005). Boarding of admitted patients in the ED accounts for a substantial portion of ED patient-care hours. Overall boarding time decreased over the 3 years. Copyright © 2010 Elsevier Inc. All rights reserved.

  11. Diversity in the Emerging Critical Care Workforce: Analysis of Demographic Trends in Critical Care Fellows From 2004 to 2014.

    Science.gov (United States)

    Lane-Fall, Meghan B; Miano, Todd A; Aysola, Jaya; Augoustides, John G T

    2017-05-01

    Diversity in the physician workforce is essential to providing culturally effective care. In critical care, despite the high stakes and frequency with which cultural concerns arise, it is unknown whether physician diversity reflects that of critically ill patients. We sought to characterize demographic trends in critical care fellows, who represent the emerging intensivist workforce. We used published data to create logistic regression models comparing annual trends in the representation of women and racial/ethnic groups across critical care fellowship types. United States Accreditation Council on Graduate Medical Education-approved residency and fellowship training programs. Residents and fellows employed by Accreditation Council on Graduate Medical Education-accredited training programs from 2004 to 2014. None. From 2004 to 2014, the number of critical care fellows increased annually, up 54.1% from 1,606 in 2004-2005 to 2,475 in 2013-2014. The proportion of female critical care fellows increased from 29.5% (2004-2005) to 38.3% (2013-2014) (p workforce reflect underrepresentation of women and racial/ethnic minorities. Trends highlight increases in women and Hispanics and stable or decreasing representation of non-Hispanic underrepresented minority critical care fellows. Further research is needed to elucidate the reasons underlying persistent underrepresentation of racial and ethnic minorities in critical care fellowship programs.

  12. Isolation of sabin-like polioviruses from wastewater in a country using inactivated polio vaccine.

    Science.gov (United States)

    Zurbriggen, Sebastian; Tobler, Kurt; Abril, Carlos; Diedrich, Sabine; Ackermann, Mathias; Pallansch, Mark A; Metzler, Alfred

    2008-09-01

    From 2001 to 2004, Switzerland switched from routine vaccination with oral polio vaccine (OPV) to inactivated polio vaccine (IPV), using both vaccines in the intervening period. Since IPV is less effective at inducing mucosal immunity than OPV, this change might allow imported poliovirus to circulate undetected more easily in an increasingly IPV-immunized population. Environmental monitoring is a recognized tool for identifying polioviruses in a community. To look for evidence of poliovirus circulation following cessation of OPV use, two sewage treatment plants located in the Zurich area were sampled from 2004 to 2006. Following virus isolation using either RD or L20B cells, enteroviruses and polioviruses were identified by reverse transcription-PCR. A total of 20 out of 174 wastewater samples were positive for 62 Sabin-like isolates. One isolate from each poliovirus-positive sample was analyzed in more detail. Sequencing the complete viral protein 1 (VP1) capsid coding region, as well as intratypic differentiation (ITD), identified 3 Sabin type 1, 13 Sabin type 2, and 4 Sabin type 3 strains. One serotype 1 strain showed a discordant result in the ITD. Three-quarters of the strains showed mutations within the 5' untranslated region and VP1, known to be associated with reversion to virulence. Moreover, three strains showed heterotypic recombination (S2/S1 and S3/S2/S3). The low number of synonymous mutations and the partial temperature sensitivity are not consistent with extended circulation of these Sabin virus strains. Nevertheless, the continuous introduction of polioviruses into the community emphasizes the necessity for uninterrupted child vaccination to maintain high herd immunity.

  13. [Increase in the incidence of invasive pneumococcal disease caused by serotype 19A prior to the implementation of the expanded pneumococcal vaccines].

    Science.gov (United States)

    González Martínez, F; Saavedra Lozano, J; Navarro Gómez, M L; Santos Sebastián, M M; Rodríguez Fernández, R; González Sánchez, M; Hernández-Sampelayo Matos, T

    2013-11-01

    To describe the epidemiology, clinical syndromes and microbiological characteristics of serotype 19A as the main cause of invasive pneumococcal disease (IPD) in children admitted to a tertiary hospital in Spain. A retrospective (1998-2004) and prospective (2005-2009) study was conducted on children with IPD produced by serotype 19A. The study was divided into three periods (P): P1 (1998-2001) when PCV7 had not been commercialized; P2 (2002-2005) with 40% vaccine coverage among children; and P3 (2006-2009) when the vaccine was added to the Childhood Immunization Schedule in Madrid. A total of 155 isolates of Streptococcus pneumoniae (SP) producing IPD were analysed, with 21 of them being serotype 19A (14%). An increased prevalence of serotype 19A was found: 2/45 cases (4.4%) in P1, 3/41 cases (7.3%) in P2 and 16/69 cases (23.2%) in P3. It occurred mostly in children younger than 2 years (16/21; 76%). This serotype was the main cause of meningitis (5/20; 25%), pleural empyema (3/22; 14%) and bacteraemic mastoiditis (2/4; 50%). Thirteen isolates (61.5%) had an MIC ≥ 0.12μ/ml for penicillin in extra-meningeal infections, and 3 of the 5 isolates causing meningitis (60%) had an MIC ≥ 1μ/ml for cefotaxime. Serotype 19A was the main causal agent of IPD in the PCV7 era (P3), with high antibiotic resistance rates. This serotype was responsible for all types of IPD, being the main cause of meningitis. Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  14. Confiabilidade e validade das Declarações de Óbito por câncer de boca no Município de Teresina, Piauí, Brasil, no período de 2004 e 2005 Reliability and validity of death certificates specifying oral cancer as cause of death in Teresina, Piauí State, Brazil, 2004-2005

    Directory of Open Access Journals (Sweden)

    Luciana Tolstenko Nogueira

    2009-02-01

    Full Text Available A política de saúde brasileira depende da precisão dos dados contidos no sistema de informação em saúde. Com objetivo de avaliar a confiabilidade e validade da causa básica de morte por uma neoplasia específica, no Município de Teresina, Piauí, Brasil, foram utilizadas todas as Declarações de Óbito (DO que possuíam como causa básica de morte o câncer de boca nos anos de 2004 e 2005, contabilizando um total de 23 DO. Elas foram submetidas à nova codificação da causa básica mediante utilização de formulário direcionado à coleta de dados clínicos e de exames complementares para a confirmação do diagnóstico nos prontuários médicos. O diagnóstico foi confirmado pelo exame histopatológico e história clínica. Observou-se uma concordância simples de 91,3% e coeficiente kappa de 0,84. O valor preditivo positivo correspondeu a 90,9%. Assim, pode-se afirmar que as referidas estatísticas de mortalidade são válidas e confiáveis. Este estudo teve como limitação possíveis sub-registros de casos que tiveram como causa básica de morte a referida patologia, visto que tais dados não constam no sistema de informação em mortalidade de Teresina.Brazilian health policy depends on the accuracy of data in the health information system. This study aimed to assess the reliability and validity of data on underlying cause of death due to a specific neoplasm in the Municipality of Teresina, Piauí State, Brazil, based on all the death certificates from 2004 and 2005 that reported oral cancer as the underlying cause of death (total of 23 death certificates. The death certificates were recoded for underlying cause of death by using a form targeted at collecting clinical and laboratory data to confirm the medical diagnosis on patient charts. Diagnosis was confirmed by histopathologic examination and clinical history. Simple agreement was 91.3%, kappa coefficient 0.84, and positive predictive value 90.9%. Based on the findings, the

  15. High-yield production of a stable Vero cell-based vaccine candidate against the highly pathogenic avian influenza virus H5N1

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Fangye; Zhou, Jian; Ma, Lei; Song, Shaohui; Zhang, Xinwen; Li, Weidong; Jiang, Shude [No. 5, Department of Bioproducts, Institute of Medical Biology, Chinese Academy of Medical Science and Pecking Union Medical College, Jiaoling Avenue 935, Kunming, Yunnan Province 650102, People' s Republic of China (China); Wang, Yue [National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Yingxin Lane 100, Xicheng District, Beijing 100052, People' s Republic of China (China); Liao, Guoyang [No. 5, Department of Bioproducts, Institute of Medical Biology, Chinese Academy of Medical Science and Pecking Union Medical College, Jiaoling Avenue 935, Kunming, Yunnan Province 650102, People' s Republic of China (China)

    2012-05-18

    Highlights: Black-Right-Pointing-Pointer Vero cell-based HPAI H5N1 vaccine with stable high yield. Black-Right-Pointing-Pointer Stable high yield derived from the YNVa H3N2 backbone. Black-Right-Pointing-Pointer H5N1/YNVa has a similar safety and immunogenicity to H5N1delta. -- Abstract: Highly pathogenic avian influenza (HPAI) viruses pose a global pandemic threat, for which rapid large-scale vaccine production technology is critical for prevention and control. Because chickens are highly susceptible to HPAI viruses, the supply of chicken embryos for vaccine production might be depleted during a virus outbreak. Therefore, developing HPAI virus vaccines using other technologies is critical. Meeting vaccine demand using the Vero cell-based fermentation process has been hindered by low stability and yield. In this study, a Vero cell-based HPAI H5N1 vaccine candidate (H5N1/YNVa) with stable high yield was achieved by reassortment of the Vero-adapted (Va) high growth A/Yunnan/1/2005(H3N2) (YNVa) virus with the A/Anhui/1/2005(H5N1) attenuated influenza vaccine strain (H5N1delta) using the 6/2 method. The reassorted H5N1/YNVa vaccine maintained a high hemagglutination (HA) titer of 1024. Furthermore, H5N1/YNVa displayed low pathogenicity and uniform immunogenicity compared to that of the parent virus.

  16. Acceptability of HPV vaccines and associations with perceptions related to HPV and HPV vaccines among men who have sex with men in Hong Kong.

    Directory of Open Access Journals (Sweden)

    Joseph T F Lau

    Full Text Available HPV vaccines are available to men but there are few studies investigating the acceptability of HPV vaccines among men who have sex with men (MSM, a high risk group. We assessed the intention to take up HPV vaccines among MSM in Hong Kong and the associated factors related to cognitions on HPV and HPV vaccines, basing on the Health Belief Model (n = 542. The acceptability of HPV vaccines was 20% (unconditional on efficacies and price, 29.2% (conditional on efficacies and market price, 51.7% (conditional on efficacies and discounted price and 79.1% (conditional on efficacies and free price. Adjusting for background variables, composite scores of perceived susceptibility, perceived severity, perceived barriers and cue to actions were significantly associated with acceptability of HPV vaccines conditional on specific efficacies and the market price. Acceptability of HPV vaccines was highly price sensitive. Future studies need to use conditional measures. Implementation and translational researches are warranted.

  17. Change in hepatitis A epidemiology after vaccinating high risk children in Taiwan, 1995-2008.

    Science.gov (United States)

    Tsou, Tsung-Pei; Liu, Cheng-Chung; Huang, Ji-Jia; Tsai, Kun-Ju; Chang, Hsiu-Fang

    2011-04-05

    Taiwan started to immunize children in 30 indigenous townships against hepatitis A since June 1995. The program was further expanded to 19 non-indigenous townships with higher incidence or increased risk of epidemic in 1997-2002, covering 2% of total population. Annual incidence of hepatitis A decreased from 2.96 in 1995 (baseline period) to 0.90/100,000 in 2003-2008 (vaccination period). The incidence in vaccinated townships and unvaccinated townships declined 98.3% (49.66-0.86/100,000) and 52.6% (1.90-0.90/100,000). In 2003-2008, incidence doubled in people aged >=30 years, mostly in unvaccinated townships (0.42-0.92). During 2003-2008, travel to endemic countries was the most commonly reported risk factor (13.5%). First dose vaccine coverage was 78.8% in 1994-2005 birth cohort. Taiwan's experience demonstrates the great, long-term efficacy of hepatitis A vaccine in disease control in vaccinated townships, and out-of-cohort effect in unvaccinated townships. Further reduction can be achieved by improving vaccination coverage of adults at risk. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Mumps vaccine effectiveness in highly immunized populations.

    Science.gov (United States)

    Domínguez, Angela; Torner, Núria; Castilla, Jesús; Batalla, Joan; Godoy, Pere; Guevara, Marcela; Carnicer, Dolors; Caylà, Joan; Rius, Cristina; Jansà, Josep Maria

    2010-04-30

    The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks. (c) 2010 Elsevier Ltd. All rights reserved.

  19. 76 FR 79203 - Prospective Grant of Exclusive License: Veterinary Biological Products for Swine Influenza Vaccines

    Science.gov (United States)

    2011-12-21

    ... Exclusive License: Veterinary Biological Products for Swine Influenza Vaccines AGENCY: National Institutes....7. The invention relates to compositions and methods of use as Veterinary Influenza Vaccines... to humans. This technology describes DNA vaccines against influenza serotypes H5N1, H1N1, H3N2, and...

  20. Green revolution vaccines, edible vaccines

    African Journals Online (AJOL)

    Admin

    of development. Food vaccines may also help to suppress autoimmunity disorders such as Type-1. Diabetes. Key words: Edible vaccines, oral vaccines, antigen expression, food vaccines. INTRODUCTION. Vaccination involves the stimulation of the immune system to prepare it for the event of an invasion from a particular ...

  1. A Cross-Sectional Study of the Association between Infant Hepatitis B Vaccine Exposure in Boys and the Risk of Adverse Effects as Measured by Receipt of Special Education Services

    Directory of Open Access Journals (Sweden)

    David A. Geier

    2018-01-01

    Full Text Available The National Center for Education Statistics reported that between 1990–2005 the number of children receiving special education services (SES rose significantly, and then, from 2004–2012, the number declined significantly. This coincided with the introduction of Thimerosal-containing hepatitis B vaccine in 1991, and the subsequent introduction of Thimerosal-reduced hepatitis B vaccine in the early 2000s. This study examined the potential relationship between infant exposure to mercury from three doses of Thimerosal-containing hepatitis B vaccine and the risk of boys being adversely affected (as measured by receipt of SES. This cross-sectional study examined 1192 boys (weighted n = 24,537,123 7–8 years of age (born: 1994–2007 from the combined 2001–2014 National Health and Nutritional Examination Survey (NHANES. Survey logistic regression modeling revealed that an exposed population receiving three doses of infant Thimerosal-containing hepatitis B vaccine (weighted n = 11,186,579, in comparison to an unexposed population (weighted n = 704,254, were at an increased risk of receipt of SES. This association was robust (crude odds ratio = 10.143, p = 0.0232, even when considering covariates, such as race and socioeconomic status (adjusted odds ratio = 9.234, p = 0.0259. Survey frequency modeling revealed that receipt of SES for the population that was exposed to three doses of Thimerosal-containing hepatitis B vaccine in infancy (12.91% was significantly higher than the unexposed population (1.44% (prevalence ratio = 8.96, p = 0.006, prevalence attributable rate = 0.1147. Despite the limitation of this cross-sectional study not being able to ascribe a direct cause-and-effect relationship between exposure and outcome, it is estimated that an additional 1.2 million boys received SES with excess education costs of about United States (US $180 billion associated with exposure to Thimerosal-containing hepatitis B vaccine. By contrast, exposure

  2. A Cross-Sectional Study of the Association between Infant Hepatitis B Vaccine Exposure in Boys and the Risk of Adverse Effects as Measured by Receipt of Special Education Services.

    Science.gov (United States)

    Geier, David A; Kern, Janet K; Homme, Kristin G; Geier, Mark R

    2018-01-12

    The National Center for Education Statistics reported that between 1990-2005 the number of children receiving special education services (SES) rose significantly, and then, from 2004-2012, the number declined significantly. This coincided with the introduction of Thimerosal-containing hepatitis B vaccine in 1991, and the subsequent introduction of Thimerosal-reduced hepatitis B vaccine in the early 2000s. This study examined the potential relationship between infant exposure to mercury from three doses of Thimerosal-containing hepatitis B vaccine and the risk of boys being adversely affected (as measured by receipt of SES). This cross-sectional study examined 1192 boys (weighted n = 24,537,123) 7-8 years of age (born: 1994-2007) from the combined 2001-2014 National Health and Nutritional Examination Survey (NHANES). Survey logistic regression modeling revealed that an exposed population receiving three doses of infant Thimerosal-containing hepatitis B vaccine (weighted n = 11,186,579), in comparison to an unexposed population (weighted n = 704,254), were at an increased risk of receipt of SES. This association was robust (crude odds ratio = 10.143, p = 0.0232), even when considering covariates, such as race and socioeconomic status (adjusted odds ratio = 9.234, p = 0.0259). Survey frequency modeling revealed that receipt of SES for the population that was exposed to three doses of Thimerosal-containing hepatitis B vaccine in infancy (12.91%) was significantly higher than the unexposed population (1.44%) (prevalence ratio = 8.96, p = 0.006, prevalence attributable rate = 0.1147). Despite the limitation of this cross-sectional study not being able to ascribe a direct cause-and-effect relationship between exposure and outcome, it is estimated that an additional 1.2 million boys received SES with excess education costs of about United States (US) $180 billion associated with exposure to Thimerosal-containing hepatitis B vaccine. By contrast, exposure to Thimerosal

  3. Dampak Perubahan Kebijakan Dagang Starbucks terhadap Perekonomian Ethiopia 2005-2008

    OpenAIRE

    Jamaan, Ahmad; Fauziah, Ana

    2014-01-01

    This research explains about how the the effect of the Starbucks policy trade changing to Ethiopian econnomy in 2005 until 2008. The purpose of this research is to know how the implementation of agreement between Ethiopian Government and Starbucks have effected to Ethiopia coffee industry. This case had been a conflict since 2004 when Ethiopian government knew their origin coffee was trademark by Strabucks in USPTO without their permission. Oxfam as Non-Government Organization that moved for ...

  4. Änderungsanalyse in den Suchergebnissen einer fachspezifischen Recherche mit den Suchmaschinen Google und Scirus: Vergleich der Jahre 2004 und 2005 für eine Fragestellung aus dem Bereich der Biotechnologie / Changes in query results from selected search engines over a time span: a comparison between 2004 and 2005 for a specific search in the field of biotechnology

    Directory of Open Access Journals (Sweden)

    Doldi, M. Luisa

    2005-12-01

    Full Text Available Aim of this work was the analysis of the changes occurring in hit lists of selected search engines at two different points of time.The same search query was applied to the search engine Google and to the science search engine Scirus in August 2004 and in April 2005. The first 40 hits of each search have been analysed on the basis of predefined qualitative and quantitative parameters. Further an analysis of overlapping between search hits at the above mentioned time points has been carried out for each search engine separately. The results of this study has shown on one hand the existence of positive trends in the result lists of both search engines (less dead links, a higher precision in results and on the other hand the role played by search engines themselves in the dynamic of result lists. The method applied here has shown to be useful for describing and measuring trends and changes in the search results of search engines over a time span.

  5. Molecular epidemiology of norovirus strains in Paraguayan children during 2004-2005: description of a possible new GII.4 cluster.

    Science.gov (United States)

    Galeano, Maria Eugenia; Martinez, Magaly; Amarilla, Alberto A; Russomando, Graciela; Miagostovich, Marize Pereira; Parra, Gabriel I; Leite, José Paulo

    2013-10-01

    Noroviruses (NoV) have been shown to be an important cause of morbidity and mortality in children worldwide, only second after Group A rotaviruses (RVA). In Paraguay, acute gastroenteritis (AGE) is the third cause of mortality in children ≤5 years old. To analyze the presence and diversity of NoV in Paraguayan children ≤5 years old presenting AGE. Three hundred seventy eight fecal samples, negative for pathogenic bacteria and RVA, were collected from children admitted as ambulatory and hospitalized patients in a large private hospital from Asuncion, Paraguay from 2004 to 2005. The presence and diversity of NoV was determined by two different RT-PCR strategies and nucleotide sequencing. One hundred and sixty one samples were positive for NoV by partial amplification of the viral polymerase gene (RdRp). No seasonality or differences in the viral prevalence for the different age-groups were detected. GII and GI NoVs were associated to 58% and 42% of the infections, respectively. The genotype was determined in 18% (29/161) NoV-positive samples. The genotypes detected were: GII.4 (18%), GII.17 (18%), GII.6 (14%), GII.7 (14%), GII.3 (10%), GII.5 (3%), GII.8 (3%), GII.16 (3%), GI.3 (14%) and GI.8 (3%). Amplification of the ORF2 from the GII.4 strains showed the presence of a new GII.4 variant. The results showed a continuous circulation of NoV in children throughout the two years of study and an extensive diversity of genotypes co-circulating, highlighting the need for better surveillance of NoV in Paraguayan children. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. The THE-QS World University Rankings, 2004 – 2009

    Directory of Open Access Journals (Sweden)

    Richard Holmes

    2010-06-01

    Full Text Available This paper reviews the origin, development and demise of the Times Higher Education Supplement (now Times Higher Education – QS Quacquarelli Symonds (QS World University Rankings between 2004 and 2009. It describes the structure and methodology of the rankings, their public impact and various criticisms that have been made. It also analyses changes that were introduced between 2005 and 2009 and concludes by noting the development of two distinct ranking systems by the magazine Times Higher Education (THE and by its former partner, the consulting company Quacquarelli Symonds.

  7. Producción científica sobre derechos sexuales y reproductivos, Colombia 1994-2004 A scientific review about sexual and reproductive rights on Colombia, 1994-2004

    OpenAIRE

    Doris Elena Ospina Muñoz; Rosa Amalia Castaño López

    2009-01-01

    Estudio realizado entre julio/2005 y julio/2008 siguiendo la Base de Productos Nacionales de COLCIENCIAS (X-acta). Objetivo: caracterizar el conocimiento producido sobre derechos sexuales y reproductivos en Colombia durante 1994-2004. Metodología: se consulta X-acta utilizando descriptores. Los artículos son organizados en tres grupos según la revista en que se publican: nacionales indexadas (T1), nacionales no indexadas (T2), extranjeras (T3). Se construyen categorías. Resultados: se identif...

  8. Analysis of phytoplankton composition from southern Malabar Coast during the 2005 monsoon as a follow-up of September 2004 stench event

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, N.; Catul, V.; Kurian, S.; Rodrigues, V.; Paul, J.T.; Fernandes, V.; Imtiaz, C.A.

    inter- site variations, though not as pronounced as in the case of Pb and Zn. An industrial site in Delhi 1 reported a high concentra- tion (1000 μg/g) of Ni. However, our re- sults are comparable with those of a rural traffic location (105 μg... University, Tezpur 784 028, India 2 Northeast Regional Institute of Water and Land Management, Tezpur 784 027, India *For correspondence. e-mail: rrh@tezu.ernet.in Analysis of phytoplankton composition from southern Malabar Coast during...

  9. Reduction of travellers' diarrhoea by WC/rBS oral cholera vaccine in young, high-risk travellers.

    Science.gov (United States)

    Torrell, Josep Ma Ramon; Aumatell, Cristina Masuet; Ramos, Sergi Morchon; Mestre, Laura Gavaldà; Salas, Carme Micheo

    2009-06-19

    A bidirectional cohort study investigates whether pre-travel vaccination with whole cell/recombinant B subunit inactivated, killed oral cholera vaccine reduces the incidence of diarrhoea in young adult travellers to high-risk areas. Risk of travellers' diarrhoea was assessed according to destination and reason for travel in high-risk travellers of a travel clinic in Barcelona, Spain. Those at high-risk between January and December 2005 were advised on water/food safety and hygiene. High-risk travellers between January and December 2006 were additionally vaccinated with WC/rBS oral cholera vaccine. Data regarding diarrhoea were gathered by structured telephone interview or e-mailed questionnaire following the travellers' return. The incidence of diarrhoea in the group vaccinated with WC/rBS oral cholera vaccine (n=321) was 17.4%, compared with 39.7% in the non-vaccinated group (n=337) (adjusted risk ratio 0.40). The first episode was significantly shorter in the vaccinated group (mean 2.3 days) than in the non-vaccinated group (mean 3.8 days) (pyoung, high-risk travellers. Vaccination with the WC/rBS oral cholera vaccine as well as food safety and hygiene advice could offer effective means of reducing the risk of diarrhoea while abroad.

  10. Viral Vectors for Use in the Development of Biodefense Vaccines

    Science.gov (United States)

    2005-06-17

    Shigella species Dengue Salmonella Filoviruses Listeria monocytogenes Ebola Campylobacter jejuni Marburg Yersinia entercolitica Viruses (Caliciviruses...Orthopoxvirus genus containing the monkey - J.S. Lee et al. / Advanced Drug Delivery Reviews 57 (2005) 1293–1314 1297 Approved for public release. Distribution...four monkeys vaccinated with V-LSGPC produced antibodies specific for LSV. After challenge, the four monkeys developed a febrile illness with low

  11. Efficacy of a Human Papillomavirus Vaccination Educational Platform in a Diverse Urban Population.

    Science.gov (United States)

    Weinstein, Jacqueline E; Ananth, Ashwin; Brunner, Jacob P; Nelson, Ryan E; Bateman, Marjorie E; Carter, John M; Buell, Joseph F; Friedlander, Paul L

    2016-06-01

    Human papillomavirus (HPV) is a preventable disease that plays a causative role in a significant proportion of malignant neoplasms of the head and neck. Inner-city populations are at risk for HPV-related oropharyngeal cancer, are least likely to receive HPV vaccination, and report a lack of information regarding HPV. To determine whether an educational platform affects knowledge, attitudes, and practices regarding HPV vaccination in an inner-city community. This prospective cohort study, conducted from March 1 to December 31, 2014, surveyed 128 participants at multiple inner-city community centers regarding their knowledge of, attitudes toward, and practices regarding HPV vaccination before and after a brief educational presentation. No eligible individuals refused to participate in the educational session. Surveys were excluded from analysis if they were incomplete. Participants completed two 20-question surveys separated by a 15-minute educational session on HPV-related disease, including a short PowerPoint presentation. Presence of statistically significant differences in survey scores before and after the educational session. Eighty-six participants met eligibility criteria (61 male [70.9%]; 68 with a high school education [79.1%]). Baseline knowledge of HPV, its causal association with cancer, and the existence of a vaccine against HPV were poor: of a total composite score of 20, the mean knowledge score before the educational session was 9.69. Participants' self-rated knowledge regarding HPV disease and vaccination improved significantly as a result of the educational session; the absolute increase in mean knowledge composite score from before the educational session to after the session was 3.52 (17.6%) (95% CI, -2.87 to 9.92; P government involvement in vaccination did not change as a result of the educational session (composite attitudes score before the educational session, 16.57 of 28; score after the session, 15.22; P = .98). Participants' intent

  12. Socio-psychological factors driving adult vaccination: a qualitative study.

    Directory of Open Access Journals (Sweden)

    Ana Wheelock

    Full Text Available While immunization is one of the most effective and successful public health interventions, there are still up to 30,000 deaths in major developed economies each year due to vaccine-preventable diseases, almost all in adults. In the UK, despite comparatively high vaccination rates among ≥65 s (73% and, to a lesser extent, at-risk ≤65 s (52% in 2013/2014, over 10,000 excess deaths were reported the previous influenza season. Adult tetanus vaccines are not routinely recommended in the UK, but may be overly administered. Social influences and risk-perceptions of diseases and vaccines are known to affect vaccine uptake. We aimed to explore the socio-psychological factors that drive adult vaccination in the UK, specifically influenza and tetanus, and to evaluate whether these factors are comparable between vaccines.20 in-depth, face-to-face interviews were conducted with members of the UK public who represented a range of socio-demographic characteristics associated with vaccination uptake. We employed qualitative interviewing approaches to reach a comprehensive understanding of the factors influencing adult vaccination decisions. Thematic analysis was used to analyze the data.Participants were classified according to their vaccination status as regular, intermittent and non-vaccinators for influenza, and preventative, injury-led, mixed (both preventative and injury-led and as non-vaccinators for tetanus. We present our finding around five overarching themes: 1 perceived health and health behaviors; 2 knowledge; 3 vaccination influences; 4 disease appraisal; and 5 vaccination appraisal.The uptake of influenza and tetanus vaccines was largely driven by participants' risk perception of these diseases. The tetanus vaccine is perceived as safe and sufficiently tested, whereas the changing composition of the influenza vaccine is a cause of uncertainty and distrust. To maximize the public health impact of adult vaccines, policy should be better

  13. PetroKazakhstan Inc. 2004 annual report : going beyond boundaries

    International Nuclear Information System (INIS)

    2005-01-01

    PetroKazakhstan is a vertically integrated Calgary-based energy company that has been involved in the acquisition, exploration and production of oil and gas in Kazakhstan. The company also has shares listed in Canada, the United States, the United Kingdom and Germany. Financial information from PetroKazakhstan was presented and a review of their 2004 operations was made available for the benefit of shareholders. The company's proved plus probable reserve base as of January 1, 2005 has been assessed at 549.8 million barrels of equivalent. In 2004, the company generated record earnings of $0.5 billion, an increase of 58 per cent from 2003. This report summarized the company's energy resource activities and presented an operations review as well as consolidated financial statements, and common share information including the accounts of PetroKazakhstan and the company's proportionate share of the assets, liabilities, revenues, expenses and cash flows. Revenue and expenditure statements were summarized by source. tabs., figs

  14. Energy in Sweden. Facts and figures 2005

    International Nuclear Information System (INIS)

    2005-12-01

    Energy in Sweden. Facts and Figures 2005 contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years (2003 and 2004). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts

  15. Hurricane impact and recovery shoreline change analysis of the Chandeleur Islands, Louisiana, USA: 1855 to 2005

    Science.gov (United States)

    Fearnley, Sarah Mary; Miner, Michael D.; Kulp, Mark; Bohling, Carl; Penland, Shea

    2009-12-01

    Results from historical (1855-2005) shoreline change analysis conducted along the Chandeleur Islands, Louisiana demonstrate that tropical cyclone frequency dominates the long-term evolution of this barrier island chain. Island area decreased at a rate of -0.16 km2/year for the relatively quiescent time period up until 1996, when an increase in tropical cyclone frequency accelerated this island area reduction to a rate of -1.01 km2/year. More frequent hurricanes also affected shoreline retreat rates, which increased from -11.4 m/year between 1922 and 1996 to -41.9 m/year between 1982 and 2005. The erosional impact caused by the passage of Hurricane Katrina in 2005 was unprecedented. Between 2004 and 2005, the shoreline of the northern islands retreated -201.5 m/year, compared with an average retreat rate of -38.4 m/year between 1922 and 2004. A linear regression analysis of shoreline change predicts that, as early as 2013, the backbarrier marsh that serves to stabilize the barrier island chain will be completely destroyed if storm frequency observed during the past decade persists. If storm frequency decreases to pre-1996 recurrence intervals, the backbarrier marsh is predicted to remain until 2037. Southern portions of the barrier island chain where backbarrier marsh is now absent behave as ephemeral islands that are destroyed after storm impacts and reemerge during extended periods of calm weather, a coastal behavior that will eventually characterize the entire island chain.

  16. Neutralizing Antibody Response in Dogs and Cats Inoculated with Commercial Inactivated Rabies Vaccines

    Science.gov (United States)

    SHIRAISHI, Rikiya; NISHIMURA, Masaaki; NAKASHIMA, Ryuji; ENTA, Chiho; HIRAYAMA, Norio

    2013-01-01

    ABSTRACT In Japan, the import quarantine regulation against rabies has required from 2005 that dogs and cats should be inoculated with the rabies vaccine and that the neutralizing antibody titer should be confirmed to be at least 0.5 international units (IU)/ml. The fluorescent antibody virus neutralization (FAVN) test is used as an international standard method for serological testing for rabies. To achieve proper immunization of dogs and cats at the time of import and export, changes in the neutralizing antibody titer after inoculation of the rabies vaccine should be understood in detail. However, few reports have provided this information. In this study, we aimed to determine evaluated, such changes by using sera from experimental dogs and cats inoculated with the rabies vaccine, and we tested samples using the routine FAVN test. In both dogs and cats, proper, regular vaccination enabled the necessary titer of neutralizing antibodies to be maintained in the long term. However, inappropriate timing of blood sampling after vaccination could result in insufficient detected levels of neutralizing antibodies. PMID:24389741

  17. High School Grade Inflation from 2004 to 2011. ACT Research Report Series, 2013 (3)

    Science.gov (United States)

    Zhang, Qian; Sanchez, Edgar I.

    2013-01-01

    This study explores inflation in high school grade point average (HSGPA), defined as trend over time in the conditional average of HSGPA, given ACT® Composite score. The time period considered is 2004 to 2011. Using hierarchical linear modeling, the study updates a previous analysis of Woodruff and Ziomek (2004). The study also investigates…

  18. Vaccination and 30-Day Mortality Risk in Children, Adolescents, and Young Adults.

    Science.gov (United States)

    McCarthy, Natalie L; Gee, Julianne; Sukumaran, Lakshmi; Weintraub, Eric; Duffy, Jonathan; Kharbanda, Elyse O; Baxter, Roger; Irving, Stephanie; King, Jennifer; Daley, Matthew F; Hechter, Rulin; McNeil, Michael M

    2016-03-01

    This study evaluates the potential association of vaccination and death in the Vaccine Safety Datalink (VSD). The study cohort included individuals ages 9 to 26 years with deaths between January 1, 2005, and December 31, 2011. We implemented a case-centered method to estimate a relative risk (RR) for death in days 0 to 30 after vaccination.Deaths due to external causes (accidents, homicides, and suicides) were excluded from the primary analysis. In a secondary analysis, we included all deaths regardless of cause. A team of physicians reviewed available medical records and coroner's reports to confirm cause of death and assess the causal relationship between death and vaccination. Of the 1100 deaths identified during the study period, 76 (7%) occurred 0 to 30 days after vaccination. The relative risks for deaths after any vaccination and influenza vaccination were significantly lower for deaths due to nonexternal causes (RR 0.57, 95% confidence interval [CI] 0.38-0.83, and RR 0.44, 95% CI 0.24-0.80, respectively) and deaths due to all causes (RR 0.72, 95% CI 0.56-0.91, and RR 0.44, 95% CI 0.28-0.65). No other individual vaccines were significantly associated with death. Among deaths reviewed, 1 cause of death was unknown, 25 deaths were due to nonexternal causes, and 34 deaths were due to external causes. The causality assessment found no evidence of a causal association between vaccination and death. Risk of death was not increased during the 30 days after vaccination, and no deaths were found to be causally associated with vaccination. Copyright © 2016 by the American Academy of Pediatrics.

  19. Five-day planetary waves in the middle atmosphere from Odin satellite data and ground-based instruments in Northern Hemisphere summer 2003, 2004, 2005 and 2007

    Directory of Open Access Journals (Sweden)

    A. Belova

    2008-11-01

    Full Text Available A number of studies have shown that 5-day planetary waves modulate noctilucent clouds and the closely related Polar Mesosphere Summer Echoes (PMSE at the summer mesopause. Summer stratospheric winds should inhibit wave propagation through the stratosphere and, although some numerical models (Geisler and Dickinson, 1976 do show a possibility for upward wave propagation, it has also been suggested that the upward propagation may in practice be confined to the winter hemisphere with horizontal propagation of the wave from the winter to the summer hemisphere at mesosphere heights causing the effects observed at the summer mesopause. It has further been proposed (Garcia et al., 2005 that 5-day planetary waves observed in the summer mesosphere could be excited in-situ by baroclinic instability in the upper mesosphere. In this study, we first extract and analyze 5-day planetary wave characteristics on a global scale in the middle atmosphere (up to 54 km in temperature, and up to 68 km in ozone concentration using measurements by the Odin satellite for selected days during northern hemisphere summer from 2003, 2004, 2005 and 2007. Second, we show that 5-day temperature fluctuations consistent with westward-traveling 5-day waves are present at the summer mesopause, using local ground-based meteor-radar observations. Finally we examine whether any of three possible sources of the detected temperature fluctuations at the summer mesopause can be excluded: upward propagation from the stratosphere in the summer-hemisphere, horizontal propagation from the winter-hemisphere or in-situ excitation as a result of the baroclinic instability. We find that in one case, far from solstice, the baroclinic instability is unlikely to be involved. In one further case, close to solstice, upward propagation in the same hemisphere seems to be ruled out. In all other cases, all or any of the three proposed mechanisms are consistent with the observations.

  20. Mass vaccination with a two-dose oral cholera vaccine in a long-standing refugee camp, Thailand.

    Science.gov (United States)

    Phares, Christina R; Date, Kashmira; Travers, Philippe; Déglise, Carole; Wongjindanon, Nuttapong; Ortega, Luis; Bhuket, Ponchanok Rattanadilok Na

    2016-01-02

    During 2005-2012, surveillance in Maela refugee camp, Thailand, identified four cholera outbreaks, with rates up to 10.7 cases per 1000 refugees. In 2013, the Thailand Ministry of Public Health sponsored a two-dose oral cholera vaccine (OCV) campaign for the approximately 46,000 refugees living in Maela. We enumerated the target population (refugees living in Maela who are ≥1 year old and not pregnant) in a census three months before the campaign and issued barcoded OCV cards to each individual. We conducted the campaign using a fixed-post strategy during two eight-day rounds plus one two-day round for persons who had missed their second dose and recorded vaccine status for each individual. To identify factors associated with no vaccination (versus at least one dose) and those associated with adverse events following immunization (AEFI), we used separate marginal log-binomial regression models with robust variance estimates to account for household clustering. A total of 63,057 OCV doses were administered to a target population of 43,485 refugees. An estimated 35,399 (81%) refugees received at least one dose and 27,658 (64%) received two doses. A total of 993 additional doses (1.5%) were wasted including 297 that were spat out. Only 0.05% of refugees, mostly children, could not be vaccinated due to repeated spitting. Characteristics associated with no vaccination (versus at least one dose) included age ≥15 years (versus 1-14 years), Karen ethnicity (versus any other ethnicity) and, only among adults 15-64 years old, male sex. Passive surveillance identified 84 refugees who experienced 108 AEFI including three serious but coincidental events. The most frequent AEFI were nausea (49%), dizziness (38%), and fever (30%). Overall, AEFI were more prevalent among young children and older adults. Our results suggest that mass vaccination in refugee camps with a two-dose OCV is readily achievable and AEFI are few. Published by Elsevier Ltd.

  1. Zika virus-like particle (VLP) based vaccine

    Science.gov (United States)

    Boigard, Hélène; Alimova, Alexandra; Martin, George R.; Katz, Al; Gottlieb, Paul

    2017-01-01

    The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders. The impact of sexual transmission is unclear but raises further concerns about virus dissemination. No specific treatment or vaccine is currently available, thus the development of a safe and effective vaccine is paramount. Here we describe a novel strategy to assemble Zika virus-like particles (VLPs) by co-expressing the structural (CprME) and non-structural (NS2B/NS3) proteins, and demonstrate their effectiveness as vaccines. VLPs are produced in a suspension culture of mammalian cells and self-assembled into particles closely resembling Zika viruses as shown by electron microscopy studies. We tested various VLP vaccines and compared them to analogous compositions of an inactivated Zika virus (In-ZIKV) used as a reference. VLP immunizations elicited high titers of antibodies, as did the In-ZIKV controls. However, in mice the VLP vaccine stimulated significantly higher virus neutralizing antibody titers than comparable formulations of the In-ZIKV vaccine. The serum neutralizing activity elicited by the VLP vaccine was enhanced using a higher VLP dose and with the addition of an adjuvant, reaching neutralizing titers greater than those detected in the serum of a patient who recovered from a Zika infection in Brazil in 2015. Discrepancies in neutralization levels between the VLP vaccine and the In-ZIKV suggest that chemical inactivation has deleterious effects on neutralizing epitopes within the E protein. This along with the inability of a VLP vaccine to cause infection makes it a preferable candidate for vaccine development. PMID:28481898

  2. Annual results 2004; Resultats annuels 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This 2004 annual evaluation of the french RTE company (electric power transport network) provides information on the 2004 results on: institutional information, financial results, customers and market, industrial resources, environment and consultation, human resources and international aspects. (A.L.B.)

  3. United States Transuranium and Uranium Registries. Annuary report, February 1, 2004 - June 30, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Alldredge, J. Richard [Washington State Univ., Richland, WA (United States); Ehrhart, Susan M. [Washington State Univ., Richland, WA (United States); Eliston, James T. [Washington State Univ., Richland, WA (United States); Emmel, Robert R. [Washington State Univ., Richland, WA (United States); Filipy, Ronald E. [Washington State Univ., Richland, WA (United States); James, Anthony C. [Washington State Univ., Richland, WA (United States); Sasser, Lyle B. [Washington State Univ., Richland, WA (United States); Wood, Tanya G. [Washington State Univ., Richland, WA (United States)

    2006-05-31

    Three events of significance to the U. S. Transuranium and Uranium Registries (USTUR) occurred during this reporting period: 1. The search for a new Associate Director was successful in that Dr. Anthony C. (Tony) James was appointed to the position, 2. A five-year grant for the operation of the USTUR was approved by the U. S. Department of Energy; the previous grant cycles were for three years, 3. I retired from the USTUR Directorship on July 1, 2005 and Tony James became the new Director.

  4. Vaccination status and sequence of vaccinations as risk factors for hospitalisation among outpatients in a high mortality country.

    Science.gov (United States)

    Biai, Sidu; Rodrigues, Amabelia; Nielsen, Jens; Sodemann, Morten; Aaby, Peter

    2011-05-09

    Most developing countries are implementing the WHO immunisation programme. Although vaccines reach most children, many modifications of the recommended schedule are observed in practice. We investigated the association between vaccination status and risk of hospitalisation in Guinea-Bissau. From May 2003 to May 2004, all consultations of children less than five years of age at the outpatient clinic of the paediatric ward at the national hospital in Bissau were registered. For each consultation, information was collected about the child's name, sex, age and socio-cultural conditions, as well as diagnosis and whether the child was hospitalised. Information about vaccinations was also registered from the child's vaccination card. We analysed the association between vaccination status and risk of hospitalisation in age intervals according to the pre-dominant vaccines. We particularly emphasised the comparison of those who had received the recommended vaccination for the age groups and those who were delayed and only had the previous vaccinations. We also examined those who had received the vaccines out of sequence. Information about vaccinations was available for 11,949 outpatient children of whom 2219 (19%) were hospitalised. Among children less than 3 months of age, unvaccinated children compared to BCG children had as expected a higher risk of hospitalisation; controlled for important determinants of hospitalisation, the hospitalisation risk ratio (HRR) was 1.99 (95% CI 1.37-2.89). In contrast, there was no difference in the HRR for children aged 1½-8 months who were delayed and had only received BCG compared to those who as recommended had received diphtheria-tetanus-pertussis (DTP) vaccine after BCG (HRR=1.10 (0.77-1.59)). In the age interval 9-17 months of age, children who were delayed and had only received DTP had significantly higher risk of hospitalisation compared with children who as recommended had measles vaccine (MV) as the most recent vaccination (HRR

  5. Annual changes in rotavirus hospitalization rates before and after rotavirus vaccine implementation in the United States.

    Science.gov (United States)

    Shah, Minesh P; Dahl, Rebecca M; Parashar, Umesh D; Lopman, Benjamin A

    2018-01-01

    Hospitalizations for rotavirus and acute gastroenteritis (AGE) have declined in the US with rotavirus vaccination, though biennial peaks in incidence in children aged less than 5 years occur. This pattern may be explained by lower rotavirus vaccination coverage in US children (59% to 73% from 2010-2015), resulting in accumulation of susceptible children over two successive birth cohorts. Retrospective cohort analysis of claims data of commercially insured US children aged rotavirus and for AGE from the 2002-2015 rotavirus seasons were examined. Median age and rotavirus vaccination coverage for biennial rotavirus seasons during pre-vaccine (2002-2005), early post-vaccine (2008-2011) and late post-vaccine (2012-2015) years. Age-stratified hospitalization rates decreased from pre-vaccine to early post-vaccine and then to late post-vaccine years. The clearest biennial pattern in hospitalization rates is the early post-vaccine period, with higher rates in 2009 and 2011 than in 2008 and 2010. The pattern diminishes in the late post-vaccine period. For rotavirus hospitalizations, the median age and the difference in age between biennial seasons was highest during the early post-vaccine period; these differences were not observed for AGE hospitalizations. There was no significant difference in vaccination coverage between biennial seasons. These observations provide conflicting evidence that incomplete vaccine coverage drove the biennial pattern in rotavirus hospitalizations that has emerged with rotavirus vaccination in the US. As this pattern is diminishing with higher vaccine coverage in recent years, further increases in vaccine coverage may reach a threshold that eliminates peak seasons in hospitalizations.

  6. Impact of rotavirus vaccination on hospitalisations in Belgium: comparing model predictions with observed data.

    Directory of Open Access Journals (Sweden)

    Baudouin Standaert

    Full Text Available BACKGROUND: Published economic assessments of rotavirus vaccination typically use modelling, mainly static Markov cohort models with birth cohorts followed up to the age of 5 years. Rotavirus vaccination has now been available for several years in some countries, and data have been collected to evaluate the real-world impact of vaccination on rotavirus hospitalisations. This study compared the economic impact of vaccination between model estimates and observed data on disease-specific hospitalisation reductions in a country for which both modelled and observed datasets exist (Belgium. METHODS: A previously published Markov cohort model estimated the impact of rotavirus vaccination on the number of rotavirus hospitalisations in children aged <5 years in Belgium using vaccine efficacy data from clinical development trials. Data on the number of rotavirus-positive gastroenteritis hospitalisations in children aged <5 years between 1 June 2004 and 31 May 2006 (pre-vaccination study period or 1 June 2007 to 31 May 2010 (post-vaccination study period were analysed from nine hospitals in Belgium and compared with the modelled estimates. RESULTS: The model predicted a smaller decrease in hospitalisations over time, mainly explained by two factors. First, the observed data indicated indirect vaccine protection in children too old or too young for vaccination. This herd effect is difficult to capture in static Markov cohort models and therefore was not included in the model. Second, the model included a 'waning' effect, i.e. reduced vaccine effectiveness over time. The observed data suggested this waning effect did not occur during that period, and so the model systematically underestimated vaccine effectiveness during the first 4 years after vaccine implementation. CONCLUSIONS: Model predictions underestimated the direct medical economic value of rotavirus vaccination during the first 4 years of vaccination by approximately 10% when assessing

  7. Mosaic protein and nucleic acid vaccines against hepatitis C virus

    Science.gov (United States)

    Yusim, Karina; Korber, Bette T. M.; Kuiken, Carla L.; Fischer, William M.

    2013-06-11

    The invention relates to immunogenic compositions useful as HCV vaccines. Provided are HCV mosaic polypeptide and nucleic acid compositions which provide higher levels of T-cell epitope coverage while minimizing the occurrence of unnatural and rare epitopes compared to natural HCV polypeptides and consensus HCV sequences.

  8. La producción española en biblioteconomía y documentación (ISI 1995-2005 Spanish literature in library and information science (isi 1995-2005

    Directory of Open Access Journals (Sweden)

    Grupo Scimago

    2006-10-01

    Full Text Available La producción de un determinado país y una determinada disciplina en el ISI Web of Knowledge, es un claro indicador de la investigación de calidad que es capaz de generar ese país en esa disciplina. En el presente artículo se analiza la producción ISI española en la categoría “Information Science and Library Science” de los últimos once años (1995-2005. Se presentan datos de producción por revista, revistas citadas, producción/citación por instituciones y producción/citación por autor. Este trabajo es la actualización de un par de artículos anteriores que cubrían el periodo 1995-2004.The scientific production of a country in a field in the ISI Web of Knowledge, is an indicator of the quality research for this country and filed. This article analyse the Spanish literature in Information Science and Library Science in the last decade (1995-2005. It presents data about production by journal, cited journals, production/citation by institutions and production/citation by author. This paper is an upgrade of a couple of former articles of the period 1995-2004.

  9. Acute disseminated encephalomyelitis onset: evaluation based on vaccine adverse events reporting systems.

    Directory of Open Access Journals (Sweden)

    Paolo Pellegrino

    Full Text Available OBJECTIVE: To evaluate epidemiological features of post vaccine acute disseminated encephalomyelitis (ADEM by considering data from different pharmacovigilance surveillance systems. METHODS: The Vaccine Adverse Event Reporting System (VAERS database and the EudraVigilance post-authorisation module (EVPM were searched to identify post vaccine ADEM cases. Epidemiological features including sex and related vaccines were analysed. RESULTS: We retrieved 205 and 236 ADEM cases from the EVPM and VAERS databases, respectively, of which 404 were considered for epidemiological analysis following verification and causality assessment. Half of the patients had less than 18 years and with a slight male predominance. The time interval from vaccination to ADEM onset was 2-30 days in 61% of the cases. Vaccine against seasonal flu and human papilloma virus vaccine were those most frequently associated with ADEM, accounting for almost 30% of the total cases. Mean number of reports per year between 2005 and 2012 in VAERS database was 40±21.7, decreasing after 2010 mainly because of a reduction of reports associated with human papilloma virus and Diphtheria, Pertussis, Tetanus, Polio and Haemophilus Influentiae type B vaccines. CONCLUSIONS: This study has a high epidemiological power as it is based on information on adverse events having occurred in over one billion people. It suffers from lack of rigorous case verification due to the weakness intrinsic to the surveillance databases used. At variance with previous reports on a prevalence of ADEM in childhood we demonstrate that it may occur at any age when post vaccination. This study also shows that the diminishing trend in post vaccine ADEM reporting related to Diphtheria, Pertussis, Tetanus, Polio and Haemophilus Influentiae type B and human papilloma virus vaccine groups is most likely not [corrected] due to a decline in vaccine coverage indicative of a reduced attention to this adverse drug reaction.

  10. Oil information 2006 - with 2005 data

    International Nuclear Information System (INIS)

    2006-01-01

    This publication serves as a comprehensive reference book on current developments in oil supply and demand. The first part contains key data on world production, trade, prices and consumption of major oil product groups, with time series back to the early 1970s.The second part gives a more detailed and comprehensive picture of oil supply, demand, trade, production and consumption by end-user for each OECD country individually and for the OECD regions. Trade data are reported extensively by origin and destination. The book/CD is one of a series of annual IEA statistical publications on major energy sources. The CD-ROM and on-line service contain detailed time series from 1960 to 2005 (end-use data only up to 2004)

  11. Kootenai River White Sturgeon Recovery Implementation Plan and Schedule; 2005-2010, Technical Report 2004-2005.

    Energy Technology Data Exchange (ETDEWEB)

    Anders, Paul

    2007-03-01

    Kootenai River white sturgeon have been declining for at least 50 years and extinction of the wild population is now imminent (Paragamian et al. 2005). Only 630 adults were estimated to remain in 2002 from a population ten times that size just 20 years ago. Significant recruitment of young sturgeon has not been observed since the early 1970s and consistent annual recruitment has not been seen since the 1950s. The remaining wild population consists of a cohort of large, old fish that is declining by about 9% per year as fish die naturally and are not replaced. At this rate, the wild population will disappear around the year 2040. Numbers have already reached critical low levels where genetic and demographic risks are acute. The Kootenai River White Sturgeon Recovery Team was convened in 1994, provided a draft Recovery Plan in 1996 and the first complete Recovery Plan for Kootenai River white sturgeon in 1999 (USFWS 1996, 1999). The Plan outlined a four part strategy for recovery, including: (1) measures to restore natural recruitment, (2) use of conservation aquaculture to prevent extinction, (3) monitoring survival and recovery, and (4) updating and revising recovery plan criteria and objectives as new information becomes available. Sturgeon recovery efforts are occurring against a backdrop of a broader ecosystem protection and restoration program for the Kootenai River ecosystem. With abundance halving time of approximately 8 years, the Kootenai River white sturgeon population is rapidly dwindling, leaving managers little time to act. Decades of study consistently indicate that recruitment failure occurs between embryo and larval stages. This assertion is based on four key observations. First, almost no recruitment has occurred during the last 30 years. Second, thousands of naturally produced white sturgeon embryos, most viable, have been collected over the past decade, resulting from an estimated 9 to 20 spawning events each year. Third, Kootenai River white

  12. A cost-benefit analysis of varicella vaccination in Aragón.

    Science.gov (United States)

    Peña Blasco, Guillermo; Blasco Pérez-Aramendía, M Jesús

    2017-10-01

    Varicella, a contagious and infectious disease that is usually benign in children, may become complicated among adults and vulnerable children and may even be life-threatening. There are effective vaccines. A retrospective study was conducted about costs and resulting hospitalizations related to this disease in the population of Aragón in the 2004-2014 period. Costs were compared to the expenses that would have been incurred if those people had received the vaccine and also to the expenses of vaccinating the 1-year-old population over the entire period. A cost-benefit analysis was done to assess the economic impact of varicella vaccination. Data for the 11-year period were provided by the Autonomous Community of Aragón (Spain) and included annual varicella incidence, hospital discharges of varicella cases, costs of primary health care visits and hospitalizations for each year, costs of each workday as per the minimum annual salary and of drugs used). Capitalized costs were estimated and compared to capitalized expenses of vaccination, and a sensitivity analysis was performed. A benefit-cost ratio of 1.6 was obtained considering that all children who had varicella had been vaccinated and had received a booster dose. A benefit-cost ratio of 1.24 was obtained considering that the vaccine had been administered to every 1-year-old individual at a price of EUR 28.59 per vaccine. Over the 11-year period, 53% of hospitalizations corresponded to children younger than 5 years old. Public campaigns for the immunization of children younger than 4 years old with 2 doses lead to cost savings and are cost-effective because the vaccine price results in a benefit-cost ratio greater than 1. A major reduction is expected in the number of hospitalizations among children aged 3-4 years. Sociedad Argentina de Pediatría

  13. Cross-reactive neutralizing antibody responses to enterovirus 71 infections in young children: implications for vaccine development.

    Directory of Open Access Journals (Sweden)

    Mei-Liang Huang

    Full Text Available BACKGROUND: Recently, enterovirus 71 (EV71 has caused life-threatening outbreaks involving neurological and cardiopulmonary complications in Asian children with unknown mechanism. EV71 has one single serotype but can be phylogenetically classified into 3 main genogroups (A, B and C and 11 genotypes (A, B1∼B5 and C1∼C5. In Taiwan, nationwide EV71 epidemics with different predominant genotypes occurred in 1998 (C2, 2000-2001 (B4, 2004-2005 (C4, and 2008 (B5. In this study, sera were collected to measure cross-reactive neutralizing antibody titers against different genotypes. METHODS: We collected historical sera from children who developed an EV71 infection in 1998, 2000, 2005, 2008, or 2010 and measured cross-reactive neutralizing antibody titers against all 11 EV71 genotypes. In addition, we aligned and compared the amino acid sequences of P1 proteins of the tested viruses. RESULTS: Serology data showed that children infected with genogroups B and C consistently have lower neutralizing antibody titers against genogroup A (>4-fold difference. The sequence comparisons revealed that five amino acid signatures (N143D in VP2; K18R, H116Y, D167E, and S275A in VP1 are specific for genogroup A and may be related to the observed antigenic variations. CONCLUSIONS: This study documented antigenic variations among different EV71 genogroups and identified potential immunodominant amino acid positions. Enterovirus surveillance and vaccine development should monitor these positions.

  14. Petrology of the 2004-2006 Mount St. Helens lava dome -- implications for magmatic plumbing and eruption triggering: Chapter 30 in A volcano rekindled: the renewed eruption of Mount St. Helens, 2004-2006

    Science.gov (United States)

    Pallister, John S.; Thornber, Carl R.; Cashman, Katharine V.; Clynne, Michael A.; Lowers, Heather; Mandeville, Charles W.; Brownfield, Isabelle K.; Meeker, Gregory P.; Sherrod, David R.; Scott, William E.; Stauffer, Peter H.

    2008-01-01

    Eighteen years after dome-forming eruptions ended in 1986, and with little warning, Mount St. Helens began to erupt again in October 2004. During the ensuing two years, the volcano extruded more than 80×106 m3 of gas-poor, crystal-rich dacite lava. The 2004-6 dacite is remarkably uniform in bulk-rock composition and, at 65 percent SiO2

  15. Cholera outbreak in Senegal in 2005: was climate a factor?

    Directory of Open Access Journals (Sweden)

    Guillaume Constantin de Magny

    Full Text Available Cholera is an acute diarrheal illness caused by Vibrio cholerae and occurs as widespread epidemics in Africa. In 2005, there were 31,719 cholera cases, with 458 deaths in the Republic of Senegal. We retrospectively investigated the climate origin of the devastating floods in mid-August 2005, in the Dakar Region of Senegal and the subsequent outbreak of cholera along with the pattern of cholera outbreaks in three other regions of that country. We compared rainfall patterns between 2002 and 2005 and the relationship between the sea surface temperature (SST gradient in the tropical Atlantic Ocean and precipitation over Senegal for 2005. Results showed a specific pattern of rainfall throughout the Dakar region during August, 2005, and the associated rainfall anomaly coincided with an exacerbation of the cholera epidemic. Comparison of rainfall and epidemiological patterns revealed that the temporal dynamics of precipitation, which was abrupt and heavy, was presumably the determining factor. Analysis of the SST gradient showed that the Atlantic Ocean SST variability in 2005 differed from that of 2002 to 2004, a result of a prominent Atlantic meridional mode. The influence of this intense precipitation on cholera transmission over a densely populated and crowded region was detectable for both Dakar and Thiès, Senegal. Thus, high resolution rainfall forecasts at subseasonal time scales should provide a way forward for an early warning system in Africa for cholera and, thereby, trigger epidemic preparedness. Clearly, attention must be paid to both natural and human induced environmental factors to devise appropriate action to prevent cholera and other waterborne disease epidemics in the region.

  16. NOVANA Arter 2004-2005

    DEFF Research Database (Denmark)

    Søgaard, B.; Pihl, S.; Wind, P.

    Mandag den 19. juni blev pdf filen af hele rapporten udskiftet. Figur 4.5.6.3 på side 129 er udskiftet, så figuren har den korrekte skala for antal individer på op til 140.000......Mandag den 19. juni blev pdf filen af hele rapporten udskiftet. Figur 4.5.6.3 på side 129 er udskiftet, så figuren har den korrekte skala for antal individer på op til 140.000...

  17. Progress Report 2004-2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-11-01

    The Faculty of Electrical Engineering and Computing (FER) as a part of University of Zagreb, has its roots in the Technical Faculty Zagreb, founded in 1919, which evolved into the Faculty of Electrical Engineering in 1956 and was upgraded into the Faculty of Electrical Engineering and Computing in 1994. Due to the increasing progress and advances in electrical and electronic engineering as well as in computer science and information technologies, the Faculty has become the largest technical faculty and the leading educational and R and D institution in the fields of electrical engineering and computing in Croatia. More than 13000 graduate students, more than 1900 postgraduate students who received the Master degree and more than 540 students with PhD degree, are today's total numbers, which highlights our highly spirited activities in teaching. Additional to this number are also 3800 undergraduate students as well as about 500 graduates each year. Organised in 11 departments, the present educational staff comprises 130 professors and 200 teaching assistants and researchers operating in more than 60 laboratories and area of more than 35000 m{sup 2}. Education and research is the crucial factor determining the economic and social progress and equality of opportunity in our societies. It becomes even more so in the digital age in order to ensure life-long-learning and the emergence of new generations of creators, researchers and entrepreneurs and to empower playing an active role in the knowledge society. The experiences at the university level should be transferred to the others. We can help to do that, as a chain the global challenge. The Faculty offers a broad spectrum of services to business and industry, from research and consultancy to conference facilities, training and postgraduate recruitment. The Faculty is a leading research-led institution and undertakes research at the highest levels of international standing. The Faculty is an integral part of the community, making a major contribution to the economic, social and cultural life of the city and region.

  18. Progress Report 2004-2005

    International Nuclear Information System (INIS)

    2005-11-01

    The Faculty of Electrical Engineering and Computing (FER) as a part of University of Zagreb, has its roots in the Technical Faculty Zagreb, founded in 1919, which evolved into the Faculty of Electrical Engineering in 1956 and was upgraded into the Faculty of Electrical Engineering and Computing in 1994. Due to the increasing progress and advances in electrical and electronic engineering as well as in computer science and information technologies, the Faculty has become the largest technical faculty and the leading educational and R and D institution in the fields of electrical engineering and computing in Croatia. More than 13000 graduate students, more than 1900 postgraduate students who received the Master degree and more than 540 students with PhD degree, are today's total numbers, which highlights our highly spirited activities in teaching. Additional to this number are also 3800 undergraduate students as well as about 500 graduates each year. Organised in 11 departments, the present educational staff comprises 130 professors and 200 teaching assistants and researchers operating in more than 60 laboratories and area of more than 35000 m 2 . Education and research is the crucial factor determining the economic and social progress and equality of opportunity in our societies. It becomes even more so in the digital age in order to ensure life-long-learning and the emergence of new generations of creators, researchers and entrepreneurs and to empower playing an active role in the knowledge society. The experiences at the university level should be transferred to the others. We can help to do that, as a chain the global challenge. The Faculty offers a broad spectrum of services to business and industry, from research and consultancy to conference facilities, training and postgraduate recruitment. The Faculty is a leading research-led institution and undertakes research at the highest levels of international standing. The Faculty is an integral part of the community, making a major contribution to the economic, social and cultural life of the city and region

  19. Bacillus Calmette-Guérin vaccination at birth

    DEFF Research Database (Denmark)

    Kjærgaard, Jesper

    2016-01-01

    to unrelated pathogens. Immune changes have been implicated in changes in both child growth and child development and for that reason we also studied these outcomes. We randomized 4262 children at birth to receive BCG vaccination at birth or to a no-intervention control group. We had pre-specified subgroup...... analyses of child sex, prematurity, and maternal BCG vaccination. The statistical analysis plan was finalized prior to unblinding of the data. Follow-up for the outcomes reported in this thesis consisted of telephone interviews and clinical examination at age 3 and 13 months, as well as online......, there was no effect of BCG on either incidence of infections, growth, body composition or psychomotor development. A subgroup analysis of children of mothers who were BCG vaccinated showed a reduced incidence of infections from 0 to 3 months among BCG vaccinated children (incidence rate ratio = 0.62, CI: 0.39 to 0...

  20. Trends in birth weight-specific and -adjusted infant mortality rates in Taiwan between 2004 and 2011.

    Science.gov (United States)

    Liang, Fu-Wen; Chou, Hung-Chieh; Chiou, Shu-Ti; Chen, Li-Hua; Wu, Mei-Hwan; Lue, Hung-Chi; Chiang, Tung-Liang; Lu, Tsung-Hsueh

    2018-06-01

    A yearly increase in the proportion of very low birth weight (VLBW) live births has resulted in the slowdown of decreasing trends in crude infant mortality rates (IMRs). In this study, we examined the trends in birth weight-specific as well as birth weight-adjusted IMRs in Taiwan. We linked three nationwide datasets, namely the National Birth Reporting Database, National Birth Certification Registry, and National Death Certification Registry databases, to calculate the IMRs according to the birth weight category. Trend tests and mortality rate ratios in the periods 2010-2011 and 2004-2005 were used to examine the extent of reduction in birth weight-specific and birth weight-adjusted IMRs. The proportion of VLBW (births increased from 0.78% in 2004-2005 to 0.89% in 2010-2011, thus exhibiting a 15% increase. The extents of the decreases in birth weight-specific IMRs in the 500-999, 1000-1499, 1500-1999, 2000-2499, and 2500-2999 g birth weight categories were 15%, 33%, 43%, 30%, and 28%, respectively, from 2004-2005 to 2010-2011. The reduction in IMR in each birth weight category was larger than the reduction in the crude IMR (13%). By contrast, the IMR in the birth weight category exhibited a 56% increase during the study period. The IMRs were calculated by excluding all live births with a birth weight of birth weight-adjusted IMRs, which were calculated using a standard birth weight distribution structure for adjustment, exhibited similar extent reductions. In countries with an increasing proportion of VLBW live births, birth weight-specific or -adjusted IMRs are more appropriate than other indices for accurately assessing the real extent of reduction in IMRs. Copyright © 2017. Published by Elsevier B.V.

  1. Standing Concertation Committee - Ordinary Meeting on 16 February 2005

    CERN Multimedia

    2005-01-01

    Original: English This meeting was devoted to the main topics summarised below. 1- MAPS The SCC took note of the numerical results of the 2004 MAPS exercise and agreed to examine a related analysis to be prepared along the same lines as those concerning the 2002 and 2003 exercises, since the introduction of MAPS. The Committee also took note of the numerical guidelines for the 2005 exercise and, in particular, of the increased allocation for periodic steps due to increased recruitment last year and demographic factors. These guidelines for 2005 will now be finalised, subject to establishing the number of additional steps that may possibly be awarded as a transitional measure. 2- Discussion on New Contract Policy The SCC held a first discussion based on an outline presented by the Management of possible approaches for a new staff contract policy. In substance, the Committee agrees that an improved and simplified policy is needed but, at this stage, there are different opinions on some of the concepts i...

  2. Vaccine decision-making begins in pregnancy: Correlation between vaccine concerns, intentions and maternal vaccination with subsequent childhood vaccine uptake.

    Science.gov (United States)

    Danchin, M H; Costa-Pinto, J; Attwell, K; Willaby, H; Wiley, K; Hoq, M; Leask, J; Perrett, K P; O'Keefe, Jacinta; Giles, M L; Marshall, H

    2017-08-12

    Maternal and childhood vaccine decision-making begins prenatally. Amongst pregnant Australian women we aimed to ascertain vaccine information received, maternal immunisation uptake and attitudes and concerns regarding childhood vaccination. We also aimed to determine any correlation between a) intentions and concerns regarding childhood vaccination, (b) concerns about pregnancy vaccination, (c) socioeconomic status (SES) and (d) uptake of influenza and pertussis vaccines during pregnancy and routine vaccines during childhood. Women attending public antenatal clinics were recruited in three Australian states. Surveys were completed on iPads. Follow-up phone surveys were done three to six months post delivery, and infant vaccination status obtained via the Australian Childhood Immunisation Register (ACIR). Between October 2015 and March 2016, 975 (82%) of 1184 mothers consented and 406 (42%) agreed to a follow up survey, post delivery. First-time mothers (445; 49%) had significantly more vaccine concerns in pregnancy and only 73% had made a decision about childhood vaccination compared to 89% of mothers with existing children (p-valuepost delivery survey, 46% and 82% of mothers reported receiving pregnancy influenza and pertussis vaccines respectively. The mother's degree of vaccine hesitancy and two attitudinal factors were correlated with vaccine uptake post delivery. There was no association between reported maternal vaccine uptake or SES and childhood vaccine uptake. First time mothers are more vaccine hesitant and undecided about childhood vaccination, and only two thirds of all mothers believed they received enough information during pregnancy. New interventions to improve both education and communication on childhood and maternal vaccines, delivered by midwives and obstetricians in the Australian public hospital system, may reduce vaccine hesitancy for all mothers in pregnancy and post delivery, particularly first-time mothers. Copyright © 2017 Elsevier Ltd

  3. How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine

    Directory of Open Access Journals (Sweden)

    Romain Paillot

    2016-11-01

    Full Text Available Vaccination is highly effective to prevent, control, and limit the impact of equine influenza (EI, a major respiratory disease of horses. However, EI vaccines should contain relevant equine influenza virus (EIV strains for optimal protection. The OIE expert surveillance panel annually reviews EIV evolution and, since 2010, the use of Florida clade 1 and 2 sub-lineages representative vaccine strains is recommended. This report summarises the development process of a fully- updated recombinant canarypox-based EI vaccine in order to meet the last OIE recommendations, including the vaccine mode of action, production steps and schedule. The EI vaccine ProteqFlu contains 2 recombinant canarypox viruses expressing the haemagglutinin of the A/equine/Ohio/03 and A/equine/Richmond/1/07 isolates (Florida clade 1 and 2 sub-lineages, respectively. The updated EI vaccine was tested for efficacy against the representative Florida clade 2 EIV strain A/equine/Richmond/1/07 in the Welsh mountain pony model. Protective antibody response, clinical signs of disease and virus shedding were compared with unvaccinated control ponies. Significant protection was measured in vaccinated ponies, which supports the vaccine registration. The recombinant canarypox-based EI vaccine was the first fully updated EI vaccine available in the EU, which will help to minimise the increasing risk of vaccine breakdown due to constant EIV evolution through antigenic drift.

  4. Effectiveness of a hepatitis A vaccination program for migrant children in Amsterdam, The Netherlands (1992-2004)

    NARCIS (Netherlands)

    Sonder, G. J. B.; Bovée, L. P. M. J.; Baayen, T. D.; Coutinho, R. A.; van den Hoek, J. A. R.

    2006-01-01

    OBJECTIVE: To evaluate the impact and effectiveness of risk-group vaccination against hepatitis A targeted at migrant children living in a country with low endemicity of hepatitis A. METHODS: Retrospective population based data analysis. Routinely collected data on hepatitis A incidence in migrant

  5. Adaptation of high-growth influenza H5N1 vaccine virus in Vero cells: implications for pandemic preparedness.

    Directory of Open Access Journals (Sweden)

    Yu-Fen Tseng

    Full Text Available Current egg-based influenza vaccine production technology can't promptly meet the global demand during an influenza pandemic as shown in the 2009 H1N1 pandemic. Moreover, its manufacturing capacity would be vulnerable during pandemics caused by highly pathogenic avian influenza viruses. Therefore, vaccine production using mammalian cell technology is becoming attractive. Current influenza H5N1 vaccine strain (NIBRG-14, a reassortant virus between A/Vietnam/1194/2004 (H5N1 virus and egg-adapted high-growth A/PR/8/1934 virus, could grow efficiently in eggs and MDCK cells but not Vero cells which is the most popular cell line for manufacturing human vaccines. After serial passages and plaque purifications of the NIBRG-14 vaccine virus in Vero cells, one high-growth virus strain (Vero-15 was generated and can grow over 10(8 TCID(50/ml. In conclusion, one high-growth H5N1 vaccine virus was generated in Vero cells, which can be used to manufacture influenza H5N1 vaccines and prepare reassortant vaccine viruses for other influenza A subtypes.

  6. Catalase epitopes vaccine design for Helicobacter pylori: A ...

    African Journals Online (AJOL)

    Jane

    2011-08-15

    Aug 15, 2011 ... colored region and P1 anchor or the starting residue of each ..... score of MVNKDVKQTT; * 1, MVNKDVKQTT is a composition of two epitopes: MVNKDVKQT and .... Therapeutic efficacy of a multi-epitope vaccine against.

  7. BCG-osis after BCG vaccination in immunocompromised children: Case series and review

    Directory of Open Access Journals (Sweden)

    Soheila Shahmohammadi

    2014-02-01

    Full Text Available Bacillus Calmette Guerin (BCG developed by Albert Calmette and Camille Guerin in France between 1908 and 1921 contained a live attenuated strain of Mycobacterium bovis and was administered worldwide to prevent tuberculosis. BCG vaccination is also administered at birth to all the newborns in Iran. Disseminated BCG infection after BCG vaccination is rare. Here in, we report 2 new cases of disseminated BCGinfection and review 15 additional cases identified from our previous retrospective study during a 5-year period from 2005-2010. All of these reported patients were vaccinated. Impaired immunity was detected in 10 cases (59% including severe combined immunodeficiency, chronic granulomatous disease, Mendelian susceptibility to mycobacterial disease, combined variable immunodeficiency, and HIV infection. Response to therapy was poor among those patients with immune deficiencies, but the overall mortality rate was 32.3%. Disseminated BCG infection is a rare but devastating complication of vaccination. Immune-compromised children are at high risk of developing BCG related complications including regional BCG-itis or disseminated disease; BCG-osis.

  8. Bacterial Artificial Chromosome Clones of Viruses Comprising the Towne Cytomegalovirus Vaccine

    Directory of Open Access Journals (Sweden)

    Xiaohong Cui

    2012-01-01

    Full Text Available Bacterial artificial chromosome (BAC clones have proven invaluable for genetic manipulation of herpesvirus genomes. BAC cloning can also be useful for capturing representative genomes that comprise a viral stock or mixture. The Towne live attenuated cytomegalovirus vaccine was developed in the 1970s by serial passage in cultured fibroblasts. Although its safety, immunogenicity, and efficacy have been evaluated in nearly a thousand human subjects, the vaccine itself has been little studied. Instead, genetic composition and in vitro growth properties have been inferred from studies of laboratory stocks that may not always accurately represent the viruses that comprise the vaccine. Here we describe the use of BAC cloning to define the genotypic and phenotypic properties of viruses from the Towne vaccine. Given the extensive safety history of the Towne vaccine, these BACs provide a logical starting point for the development of next-generation rationally engineered cytomegalovirus vaccines.

  9. Bacterial artificial chromosome clones of viruses comprising the towne cytomegalovirus vaccine.

    Science.gov (United States)

    Cui, Xiaohong; Adler, Stuart P; Davison, Andrew J; Smith, Larry; Habib, El-Sayed E; McVoy, Michael A

    2012-01-01

    Bacterial artificial chromosome (BAC) clones have proven invaluable for genetic manipulation of herpesvirus genomes. BAC cloning can also be useful for capturing representative genomes that comprise a viral stock or mixture. The Towne live attenuated cytomegalovirus vaccine was developed in the 1970s by serial passage in cultured fibroblasts. Although its safety, immunogenicity, and efficacy have been evaluated in nearly a thousand human subjects, the vaccine itself has been little studied. Instead, genetic composition and in vitro growth properties have been inferred from studies of laboratory stocks that may not always accurately represent the viruses that comprise the vaccine. Here we describe the use of BAC cloning to define the genotypic and phenotypic properties of viruses from the Towne vaccine. Given the extensive safety history of the Towne vaccine, these BACs provide a logical starting point for the development of next-generation rationally engineered cytomegalovirus vaccines.

  10. GSF - Forschungszentrum fuer Umwelt und Gesundheit. Annual report 2004; GSF - Forschungszentrum fuer Umwelt und Gesundheit. Jahresbericht 2004

    Energy Technology Data Exchange (ETDEWEB)

    Wiedemann, M.; Haury, H.J.; Goedde, M.; Guldner, H.; Kettembeil, S.; Leser, B.; Meyer-Streng, O. (eds.)

    2005-07-01

    Recent years have been shaped by the introduction of programme-oriented funding. In 2004, we were able once again to focus on the real goal of the GSF, the performance of excellent research. The effects of fine particles, for example, are at the centre of public interest. This topic is not only of great importance for health, it also has a wide-reaching economic significance; we have only to think of filters for diesel engines. The GSF was involved in many scientific successes. For example, the results on the economic costs of smoking received considerable attention from both the general public and the scientific world. GSF scientists were involved in the decoding of the chicken genome and the discovery of a Parkinson gene. Together with university and other research organisations, they founded a Virtual Institute on Biotic Interactions, and took part in an international project on the development of combination vaccines against HIV. The setting up of the GSF 'glass laboratory', which was created with substantial support form the Helmholtz Association, is particularly worthy of mention. GSF scientists have been awarded various prizes, for example the Felix Wankel Prize awarded to Professor Jean-Marie Buerstedde. The Bavarian Advancement of Women Prize 2004, which distinguished exemplary initiatives in the area of family and women's advancement, was a special honour. Professor Magdalena Goetz was appointed Director of the Institute for Stem Cell Research. (orig.)

  11. y ERB-2 asociados al pronóstico del cáncer de mama en la población de Barranquilla (2004- 2005

    Directory of Open Access Journals (Sweden)

    Luz Alba Silvera Arenas

    2007-01-01

    Full Text Available Objetivo: Estudiar los patrones de expresión de los receptores de estrógenos, progestagenos y erb-2 en 85 pacientes atendidas en dos laboratorios de patología de Barranquilla. De Julio del 2004 a diciembre del 2005. Material y metodos: Estudio Descriptivo de corte. Se utilizaron 85 muestras incluidas en parafina de pacientes con diagnóstico de cáncer de mama para lo cual, se realizaron estudios inmunohistoquimicos con técnicas de peroxidasa – antiperoxidasa, se utilizaron anticuerpos monoclonales Dako contra estrógenos, progestágenos y ebr-2. Resultados: Se observó carcinoma in situ (4, cáncer mesenquimal (1, carcinoma lobulillar (1 y resto carcinomas ductales infiltrantes grados I, II y III. La inmunohistoquímica mostró positividad para estrógeno y progestágeno a nivel intracelular en 73 casos y negativos para erb-2, 11 fueron negativos para estrógeno y progestágeno, uno fue positivo para ebr-2. Conclusiones: 1. El carcinoma ductal infiltrante grado II y III fue la forma histológica que se presentó con mayor frecuencia (80 casos. 2. El 88,23 % de los casos fueron estrógeno y progestágeno positivos. 3. La relación entre el componente histológico y receptores hormonales positivos, sugieren buen pronóstico.

  12. Quadrivalent human papillomavirus vaccination in girls and the risk of autoimmune disorders: the Ontario Grade 8 HPV Vaccine Cohort Study

    Science.gov (United States)

    Liu, Erin Y.; Smith, Leah M.; Ellis, Anne K.; Whitaker, Heather; Law, Barbara; Kwong, Jeffrey C.; Farrington, Paddy

    2018-01-01

    BACKGROUND: Despite demonstrated effectiveness in real-world settings, concerns persist regarding the safety of the quadrivalent human papillomavirus (HPV4) vaccine. We sought to assess the risk of autoimmune disorders following HPV4 vaccination among grade 8 girls eligible for Ontario’s school-based HPV vaccination program. METHODS: We undertook a population-based retrospective cohort study using Ontario’s administrative health and vaccination databases from 2007 to 2013. The self-controlled case series method was used to compare the rate of a composite end point of autoimmune disorders diagnosed during days 7–60 post-vaccination (“exposed” follow-up) to that at any other time (“unexposed”). The analysis was repeated to assess the effect of a history of immune-mediated diseases and time since vaccination. We also conducted an exploratory analysis of individual autoimmune disorders. Rate ratios and 95% confidence intervals (CIs) were estimated using conditional Poisson regression, adjusted for age, seasonality, concomitant vaccinations and infections. RESULTS: The study cohort consisted of 290 939 girls aged 12–17 years who were eligible for vaccination between 2007 and 2013. There was no significant risk for developing an autoimmune disorder following HPV4 vaccination (n = 681; rate ratio 1.12, 95% CI 0.85–1.47), and the association was unchanged by a history of immune-mediated disorders and time since vaccination. Exploratory analyses of individual autoimmune disorders found no significant risks, including for Bell palsy (n = 65; rate ratio 1.73, 95% CI 0.77–3.89), optic neuritis (n = 67; rate ratio 1.57, 95% CI 0.74–3.33) and Graves disease (n = 47; rate ratio 1.55, 95% CI 0.92–2.63). INTERPRETATION: We did not observe an increased risk of autoimmune disorders following HPV4 vaccination among teenaged girls. These findings should reassure parents and health care providers. PMID:29807937

  13. Modeling the environmental suitability of anthrax in Ghana and estimating populations at risk: Implications for vaccination and control.

    Science.gov (United States)

    Kracalik, Ian T; Kenu, Ernest; Ayamdooh, Evans Nsoh; Allegye-Cudjoe, Emmanuel; Polkuu, Paul Nokuma; Frimpong, Joseph Asamoah; Nyarko, Kofi Mensah; Bower, William A; Traxler, Rita; Blackburn, Jason K

    2017-10-01

    Anthrax is hyper-endemic in West Africa. Despite the effectiveness of livestock vaccines in controlling anthrax, underreporting, logistics, and limited resources makes implementing vaccination campaigns difficult. To better understand the geographic limits of anthrax, elucidate environmental factors related to its occurrence, and identify human and livestock populations at risk, we developed predictive models of the environmental suitability of anthrax in Ghana. We obtained data on the location and date of livestock anthrax from veterinary and outbreak response records in Ghana during 2005-2016, as well as livestock vaccination registers and population estimates of characteristically high-risk groups. To predict the environmental suitability of anthrax, we used an ensemble of random forest (RF) models built using a combination of climatic and environmental factors. From 2005 through the first six months of 2016, there were 67 anthrax outbreaks (851 cases) in livestock; outbreaks showed a seasonal peak during February through April and primarily involved cattle. There was a median of 19,709 vaccine doses [range: 0-175 thousand] administered annually. Results from the RF model suggest a marked ecological divide separating the broad areas of environmental suitability in northern Ghana from the southern part of the country. Increasing alkaline soil pH was associated with a higher probability of anthrax occurrence. We estimated 2.2 (95% CI: 2.0, 2.5) million livestock and 805 (95% CI: 519, 890) thousand low income rural livestock keepers were located in anthrax risk areas. Based on our estimates, the current anthrax vaccination efforts in Ghana cover a fraction of the livestock potentially at risk, thus control efforts should be focused on improving vaccine coverage among high risk groups.

  14. Modeling the environmental suitability of anthrax in Ghana and estimating populations at risk: Implications for vaccination and control.

    Directory of Open Access Journals (Sweden)

    Ian T Kracalik

    2017-10-01

    Full Text Available Anthrax is hyper-endemic in West Africa. Despite the effectiveness of livestock vaccines in controlling anthrax, underreporting, logistics, and limited resources makes implementing vaccination campaigns difficult. To better understand the geographic limits of anthrax, elucidate environmental factors related to its occurrence, and identify human and livestock populations at risk, we developed predictive models of the environmental suitability of anthrax in Ghana. We obtained data on the location and date of livestock anthrax from veterinary and outbreak response records in Ghana during 2005-2016, as well as livestock vaccination registers and population estimates of characteristically high-risk groups. To predict the environmental suitability of anthrax, we used an ensemble of random forest (RF models built using a combination of climatic and environmental factors. From 2005 through the first six months of 2016, there were 67 anthrax outbreaks (851 cases in livestock; outbreaks showed a seasonal peak during February through April and primarily involved cattle. There was a median of 19,709 vaccine doses [range: 0-175 thousand] administered annually. Results from the RF model suggest a marked ecological divide separating the broad areas of environmental suitability in northern Ghana from the southern part of the country. Increasing alkaline soil pH was associated with a higher probability of anthrax occurrence. We estimated 2.2 (95% CI: 2.0, 2.5 million livestock and 805 (95% CI: 519, 890 thousand low income rural livestock keepers were located in anthrax risk areas. Based on our estimates, the current anthrax vaccination efforts in Ghana cover a fraction of the livestock potentially at risk, thus control efforts should be focused on improving vaccine coverage among high risk groups.

  15. A scientific review about sexual and reproductive rights on Colombia, 1994-2004

    OpenAIRE

    Ospina Muñoz, Doris Elena; Castaño López, Rosa Amalia

    2009-01-01

    Estudio realizado entre julio/2005 y julio/2008 siguiendo la Base de Productos Nacionales de COLCIENCIAS (X-acta). Objetivo: caracterizar el conocimiento producido sobre derechos sexuales y reproductivos en Colombia durante 1994-2004. Metodología: se consulta X-acta utilizando descriptores. Los artículos son organizados en tres grupos según la revista en que se publican: nacionales indexadas (T1), nacionales no indexadas (T2), extranjeras (T3). Se construyen categorías. Resultados...

  16. Assessment of persistence and residue of diazinon and malathion in three rivers (Mond, Shahpour and Dalaky of Bushehr Province 2004-2005

    Directory of Open Access Journals (Sweden)

    Mansooreh Shayeghi

    2007-09-01

    Full Text Available Background: Water contamination due to insecticides, often generates dangerous results for consumers. Immoderate consumption of insecticides in neighboring farms contaminates rivers. Assessment of residue of phosphorus insecticides which are used in farms near rivers can play a key role in preventing probable poisonings and aquatic ecosystems polution. Methods: In this case control study, water of three permanent rivers in Bushehr province and urban water pipe network of Bushehr city were assessed in different months in 2004-2005 and 216 samples were collected on the whole. In each river,three stations were used for sampling. After the sampling, extraction processes were accomplished using solvents such as: acetone, methylen-chloride and benzene. For detection and measurement of TLC Scanner apparatus was used. Results: Residues of diazinon and malathion were found in water of the three rivers in spring and summer. And in other seasons the rate of residues were very low or zero. The statistical analysis of the results through one-sidedanalysis variance, showed that diazinon and malathion residues in the water of the surveyed rivers in different months had significant difference (p 0.05, while malathion residue was significant (p <0.05. Conclusion: In the first and second months after applying the two insecticides, their residues level in all three rivers of Mond, Shahpour and Dalaky are more than acceptable contamination level, the higher levels belong to diazinon. Precautions must be considered in using the water for drinking purposes and also using aquatic foods which are provided from these rivers.

  17. Technical Scope and Approach for the 2004 Composite Analysis of Low Level Waste Disposal at the Hanford Site

    International Nuclear Information System (INIS)

    Kincaid, Charles T.; Bryce, Robert W.; Buck, John W.

    2004-01-01

    A composite analysis is required by U.S. Department of Energy (DOE) Manual 435.1-1 to ensure public safety through the management of active and planned low-level radioactive waste disposal facilities associated with the Hanford Site (DOE/HQ-Manual 435.1-1). A Composite Analysis is defined as ''a reasonably conservative assessment of the cumulative impact from active and planned low-level waste disposal facilities, and all other sources from radioactive contamination that could interact with the low-level waste disposal facility to affect the dose to future members of the public''. At the Hanford Site, a composite analysis is required for continued disposal authorization for the immobilized low-activity waste, tank waste vitrification plant melters, low level waste in the 200 East and 200 West Solid Waste Burial Grounds, and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) waste in the Environmental Restoration Disposal Facility. The 2004 Composite Analysis will be a site-wide analysis, considering final remedial actions for the Columbia River corridor and the Central Plateau at the Hanford Site. The river corridor includes waste sites and facilities in each of the 100 Areas as well as the 300, 400, and 600 Areas. The remedial actions for the river corridor are being conducted to meet residential land use standards with the vision of the river corridor being devoted to a combination of recreation and preservation. The ''Central Plateau'' describes the region associated with operations and waste sites of the 200 Areas. DOE is developing a strategy for closure of the Central Plateau area by 2035. At the time of closure, waste management activities will shrink to a Core Zone within the Central Plateau. The Core Zone will contain the majority of Hanford's permanently disposed waste

  18. Independent review of the SaskPower rate proposal of August 2004 : final report

    International Nuclear Information System (INIS)

    Ewing, J.D.; Buhr, L.A.

    2004-01-01

    This paper presents an independent review of SaskPower's request for an increase in rates effective September 1, 2004 and September 1, 2005. With the exception of manufacturing customers, whose rate increase will be phased in over four years, these rate changes will result in a 9 per cent system average increase in 2004 and a 1.8 per cent system average increase in 2005. The report presents an introduction and description of the terms of reference for this review; a financial outlook and comparisons; system operational analysis; an analysis of expenditures; revenue requirement; cost of service issues; and rate design. The report also presents a summary and recommendations on cost of service and rate design issues. The report concluded that the scope of this review does not lend itself to a definitive conclusion on the appropriateness of the cost of service model and its application by SaskPower. Several areas needing further attention include: net fuel and purchased power allocations to different classes; allocation of rate base and in particular distribution rate base to various classes; target ratios for revenue to revenue requirements and the subsequent return on rate base percentages for each class; and demand/energy/customer components of revenue requirements compared to billing revenues. refs., 31 tabs., 1 fig., 6 appendices

  19. [The best of clinical cardiovascular pharmacology in 2005].

    Science.gov (United States)

    Ambrosi, R; Andrejak, M; Drici, M D; Herpin, D

    2006-01-01

    Although the year 2005 has reinforced the therapeutic advances of 2004, with confirmation of certain concepts, the 'coxib affair' has continued to provoke arguments between pharmaceutical companies, licensing agencies as well as patients, some of whom have amalgamated into consumer groups to reject en masse placing any responsibility on the prescribers in favour of an attack on the drug licensing process itself. Among the cardiovascular drugs that will soon be licensed, only ivabradine in stable angina, and remodulin in primary pulmonary arterial hypertension are new. The therapeutic advances in 2005 regarding platelet aggregation and blood coagulation have been significant, in the human, scientific and commercial context, while hypertension has not been ignored. Another new development is the ever more precise notion of the metabolic syndrome, a target of choice for the pharmaceutical industry. The potential range of applications has been widened to include obesity, hypertension, diabetes, HDL cholesterol... The licensing authorities find themselves facing a hurdle to overcome, with novel combinations of drugs (ACE inhibitors, calcium blockers/statins, statins/aspirin, ARA2/calcium blockers...).

  20. The Epidemiology of Stress Fractures in Collegiate Student-Athletes, 2004-2005 Through 2013-2014 Academic Years.

    Science.gov (United States)

    Rizzone, Katherine H; Ackerman, Kathryn E; Roos, Karen G; Dompier, Thomas P; Kerr, Zachary Y

    2017-10-01

      Stress fractures are injuries caused by cumulative, repetitive stress that leads to abnormal bone remodeling. Specific populations, including female athletes and endurance athletes, are at higher risk than the general athletic population. Whereas more than 460 000 individuals participate in collegiate athletics in the United States, no large study has been conducted to determine the incidence of stress fractures in collegiate athletes.   To assess the incidence of stress fractures in National Collegiate Athletic Association (NCAA) athletes and investigate rates and patterns overall and by sport.   Descriptive epidemiology study.   National Collegiate Athletic Association institutions.   National Collegiate Athletic Association athletes.   Data were analyzed from the NCAA Injury Surveillance Program for the academic years 2004-2005 through 2013-2014. We calculated rates and rate ratios (RRs) with 95% confidence intervals (CIs).   A total of 671 stress fractures were reported over 11 778 145 athlete-exposures (AEs) for an overall injury rate of 5.70 per 100 000 AEs. The sports with the highest rates of stress fractures were women's cross-country ( 28.59/100  000 AEs), women's gymnastics ( 25.58/100  000 AEs), and women's outdoor track ( 22.26/100  000 AEs). Among sex-comparable sports (baseball/softball, basketball, cross-country, ice hockey, lacrosse, soccer, swimming and diving, tennis, indoor track, and outdoor track), stress fracture rates were higher in women (9.13/100 000 AEs) than in men (4.44/100 000 AEs; RR = 2.06; 95% CI = 1.71, 2.47). Overall, stress fracture rates for these NCAA athletes were higher in the preseason (7.30/100 000 AEs) than in the regular season (5.12/100 000 AEs; RR = 1.43; 95% CI = 1.22, 1.67). The metatarsals (n = 254, 37.9%), tibia (n = 147, 21.9%), and lower back/lumbar spine/pelvis (n = 81, 12.1%) were the most common locations of injury. Overall, 21.5% (n = 144) of stress fractures were

  1. The academic majors of students taking American soil science classes: 2004-2005 to 2013-2014 academic years

    Science.gov (United States)

    Brevik, Eric C.; Vaughan, Karen L.; Parikh, Sanjai J.; Dolliver, Holly; Lindbo, David; Steffan, Joshua J.; Weindorf, David; McDaniel, Paul; Mbila, Monday; Edinger-Marshall, Susan

    2017-04-01

    Many papers have been written in recent years discussing the interdisciplinary and transdisciplinary aspects of soil science. Therefore, it would make sense that soil science courses would be taken by students in a wide array of academic majors. To investigate this, we collected data from eight different American universities on the declared academic majors of students enrolled in soil science courses over a 10 year time period (2004-2005 to 2013-2014 academic years). Data was collected for seven different classes taught at the undergraduate level: introduction to soil science, soil fertility, soil management, pedology, soil biology/microbiology, soil chemistry, and soil physics. Overall trends and trends for each class were evaluated. Generally, environmental science and crop science/horticulture/agronomy students were enrolled in soil science courses in the greatest numbers. Environmental science and engineering students showed rapid increases in enrollment over the 10 years of the study, while the number of crop science/ horticulture/ agronomy students declined. In the introduction to soil science classes, environmental science and crop science/ horticulture/ agronomy students were enrolled in the greatest numbers, while declared soil science majors only made up 6.6% of the average enrollment. The highest enrollments in soil fertility were crop science/ horticulture/ agronomy students and other agricultural students (all agricultural majors except crop science, horticulture, agronomy, or soil science). In both the soil management and pedology classes, environmental science and other agricultural students were the largest groups enrolled. Other agricultural students and students from other majors (all majors not otherwise expressly investigated) were the largest enrolled groups in soil biology/microbiology courses, and environmental science and soil science students were the largest enrolled groups in soil chemistry classes. Soil physics was the only class

  2. Vaccines today, vaccines tomorrow: a perspective.

    Science.gov (United States)

    Loucq, Christian

    2013-01-01

    Vaccines are considered as one of the major contributions of the 20th century and one of the most cost effective public health interventions. The International Vaccine Institute has as a mission to discover, develop and deliver new and improved vaccines against infectious diseases that affects developing nations. If Louis Pasteur is known across the globe, vaccinologists like Maurice Hilleman, Jonas Salk and Charles Mérieux are known among experts only despite their contribution to global health. Thanks to a vaccine, smallpox has been eradicated, polio has nearly disappeared, Haemophilus influenzae B, measles and more recently meningitis A are controlled in many countries. While a malaria vaccine is undergoing phase 3, International Vaccine Institute, in collaboration with an Indian manufacturer has brought an oral inactivated cholera vaccine to pre-qualification. The field of vaccinology has undergone major changes thanks to philanthropists such as Bill and Melinda Gates, initiatives like the Decade of Vaccines and public private partnerships. Current researches on vaccines have more challenging targets like the dengue viruses, malaria, human immunodeficiency virus, the respiratory syncytial virus and nosocomial diseases. Exciting research is taking place on new adjuvants, nanoparticles, virus like particles and new route of administration. An overcrowded infant immunization program, anti-vaccine groups, immunizing a growing number of elderlies and delivering vaccines to difficult places are among challenges faced by vaccinologists and global health experts.

  3. Quality of groundwater at and near an aquifer storage and recovery site, Bexar, Atascosa, and Wilson Counties, Texas, June 2004-August 2008

    Science.gov (United States)

    Otero, Cassi L.; Petri, Brian L.

    2010-01-01

    recovery wells likely indicate some degree of mixing of the two waters occurred rather than continued decay of radium-226 in the injected water. Geochemical and isotope data measured in samples collected in May 2005 from two Carrizo aquifer monitoring wells and in July 2008 from the three ASR production-only wells in the northern section of the ASR site indicate that injected Edwards aquifer water had not migrated to these five sites. Geochemical and isotope data measured in samples collected from Carrizo aquifer wells in 2004, 2005, and 2008 were graphically analyzed to determine if changes in chemistry could be detected. Major-ion, trace element, and isotope chemistry varied spatially in the samples collected from the Carrizo aquifer. With the exception of a few samples, major-ion concentrations measured in samples collected in Carrizo aquifer wells in 2004, 2005, and 2008 were similar. A slightly larger sulfate con-centration and a slightly smaller bicarbonate concentration were measured in samples collected in 2005 and 2008 from well NC1 compared to samples collected at well NC1 in 2004. Larger sodium concentrations and smaller calcium, magnesium, bicarbonate, and sulfate concentrations were measured in samples collected in 2008 from well WC1 than in samples collected at this well in 2004 and 2005. Larger calcium and magnesium concentrations and a smaller sodium concentration were measured in the samples collected in 2008 at well EC2 compared to samples collected at this well in 2004 and 2005. While in some cases the computed percent differences (compared to concentrations from June 2004) in dissolved iron and dissolved manganese concentrations in 11 wells sampled in the Carrizo aquifer in 2005 and 2008 were quite large, no trends that might have been caused by migration of injected Edwards aquifer water were observed. Because of the natural variation in geochemical data in the Carrizo aquifer and the small data set collected for this study, differences in major

  4. Universal vaccination of children against hepatitis A in Chile: a cost-effectiveness study.

    Science.gov (United States)

    Quezada, Arnoldo; Baron-Papillon, Florence; Coudeville, Laurent; Maggi, Leonardo

    2008-05-01

    To evaluate the healthcare and economic impact of routine hepatitis A vaccination of toddlers in Chile. We used a dynamic model of hepatitis A infection to evaluate the impact of a two-dose vaccination program, administered at ages 12 and 18 months. The model incorporated the changing epidemiology of hepatitis A in Chile and the development of vaccine-induced herd immunity. Our analysis was conducted from the public payer perspective, and an estimation of the societal perspective was performed. Costs are expressed in 2005 U.S. dollars. Vaccination of toddlers rapidly reduced the healthcare burden of hepatitis A. In the base case (95% vaccination coverage, 100-year time horizon, 1% annual decrease in force of infection), the average number of infections fell by 76.6% annually, and associated deaths fell by 59.7%. Even at 50% coverage, the program reduced infection rates substantially. Routine vaccination of toddlers had economic as well as health benefits, saving $4,984 per life-year gained (base case scenario). The program became cost saving after 6 years, and its overall cost-effectiveness per life-year gained was largely unaffected by changes in disease-related costs, herd immunity, coverage rate, and annual decrease in force of infection. Routine vaccination of toddlers will reduce the rates of symptomatic hepatitis A and associated mortality. The two-dose schedule evaluated here will be less expensive than disease-related costs in the absence of vaccination from the sixth year of its implementation. These findings support the establishment of a routine vaccination program for toddlers in Chile.

  5. Impact of change in maternal age composition on the incidence of Caesarean section and low birth weight: analysis of delivery records at a tertiary hospital in Tanzania, 1999–2005

    Directory of Open Access Journals (Sweden)

    Kidanto Hussein L

    2009-07-01

    Full Text Available Abstract Background Previous studies on change in maternal age composition in Tanzania do not indicate its impact on adverse pregnancy outcomes. We sought to establish temporal changes in maternal age composition and their impact on annual Caesarean section (CS and low birth weight deliveries (LBWT at Muhimbili National Hospital in Tanzania. Methods We conducted data analysis of 91,699 singleton deliveries that took place in the hospital between 1999 and 2005. The data were extracted from the obstetric data base. Annual proportions of individual age groups were calculated and their trends over the years studied. Multiple logistic analyses were conducted to ascertain trends in the risks of CS and LBWT. The impact of age composition changes on CS and LBWT was estimated by calculating annual numbers of these outcomes with and without the major changes in age composition, all others remaining equal. In all statistics, a p value Results The proportion of teenage mothers (12–19 years progressively decreased over time while that of 30–34 years age group increased. From 1999, the risk of Caesarean delivery increased steadily to a maximum in 2005 [adjusted OR = 1.7; 95%CI (1.6–1.8] whereas that of LBWT declined to a minimum in 2005 (adjusted OR = 0.76; 95% CI (0.71–0.82. The current major changes in age trend were responsible for shifts in the number of CS of up to206 cases per year. Likewise, the shift in LBWT was up to 158 cases per year, but the 30–34 years age group had no impact on this. Conclusion The population of mothers giving birth at MNH is progressively becoming older with substantial impact on the incidence of CS and LBWT. Further research is needed to estimate the health cost implications of this change.

  6. The world energy demand in 2005: confirmed increase in energy consumptions, despite soaring crude oil prices

    International Nuclear Information System (INIS)

    Chateau, Bertrand

    2006-01-01

    The world energy demand growth remains strong: 2004 experienced the highest growth since 19987, and brent prices had moderate impact in 2005: Very strong rise of energy consumptions despite high oil prices, Economic situation still favorable, Evolutions principally due to China. 2005 world energy consumption: 11,4 Gtoe: Asia accounts for 35% of the world energy consumption, China's weight (15%) continues to increase by one point every year (+5 points since 2000). Asia increases its pressure on the world energy growth in 2005: China accounts for almost half of the world energy consumption increase in 2005, the whole Asia accounts for 70%; The European consumption growth represents less than 5% of China's Growth; The American energy consumption decreases for the first time. 2005 world consumption by energy: With an increasing market share by 0,7 points, coal penetration increases; The oil market has lost 0,4 point, with an accelerating relative decrease; The relative weight of gas remains stable, with 21%. Energy efficiency and energy intensity of GDP: Slow-down of the world energy intensity decrease since 2001, whereas the economic growth is faster, due to changes in trends in China (increase in the recent years). Increase less sharp in China in 2005 (price effect). Energy intensity trends of GDP: Fast decrease in CIS since the recovery of the economic growth; Slow-down of the decrease in EU since 2000 and recovery in 2005 whereas the decrease has accelerated in the USA. Since 2000, the energy consumption increases less rapidly than the GDP almost everywhere, except for the Middle East. Projections until 2020: China and India could represent one third of the world energy growth, the whole of Asia more than 50%; Growth prospects for energy demand are low in the EU and CIS; America would account for 20% of the world energy growth (8% USA); In the rest of the world, high growth in Africa and in the Middle East. Gas could cover more than 40% of the world energy

  7. Mortalidad en México por influenza y neumonía (1990-2005 Mortality due to influenza and pneumonia in Mexico between 1990 and 2005

    Directory of Open Access Journals (Sweden)

    Pablo Kuri-Morales

    2006-10-01

    Full Text Available OBJETIVO: Estimar el impacto de la vacuna contra la influenza en personas menores de dos años y mayores de 65, a través del análisis de la mortalidad por influenza y neumonía en la República mexicana entre 1990 y 2005, y determinar el patrón estacional de comportamiento de la mortalidad, la tendencia de mortalidad por volumen de defunciones por periodo estacional y la velocidad de mortalidad. MATERIAL Y MÉTODOS: Los datos se tomaron del Sistema Epidemiológico y Estadístico de Defunciones (SEED-SSA. RESULTADOS: El análisis mostró una tendencia de defunciones a la baja con una rapidez respectiva de 509 y 29 defunciones menos por año, así como una interrupción de la tendencia ascendente de la mortalidad por la vacunación. CONCLUSIONES: La intervención por vacunación tiene costos positivos, tanto económicos como de calidad de vida, por lo que su implementación debe considerarse en un contexto que refleje una menor incidencia de hospitalizaciones y muertes.OBJECTIVE: To estimate the impact of influenza vaccine in infants less than two years of age and in elders more than sixty-five years of age, through the analysis of mortality due to influenza and pneumonia in Mexico, between 1990 and 2005. To determine the seasonal pattern of mortality, the tendency of mortality by volume of deaths per seasonal period, and the speed rate of mortality. MATERIAL AND METHODS: Data were taken from the Epidemiological and Statistical Mortality System (SEED-SSA per its abbreviation in Spanish. RESULTS AND CONCLUSIONS: The analysis showed there is a tendency of deaths decrease at a rate of 509 deaths less per year in the infants group and 29 deaths less in the elders group. Also, the ascending tendency of mortality was interrupted by vaccination. The vaccination intervention has a positive economic effect and also helps improve the quality of life. Therefore, its implementation is expected to lower hospital admissions and deaths.

  8. [Migrant vaccinations in Poland].

    Science.gov (United States)

    Sakowski, Piotr

    2012-01-01

    After the European Union accession in 2004, Poland has been perceived by foreigners as an attractive destination of their migration, and also as a popular transit country for people going further to the Western Europe countries. The Nofer Institute of Occupational Medicine is involved in the implementation of the international project PROMOVAX (Promote Vaccinations among Migrant Populations in Europe). The objective of the project is to promote immunizations among migrant populations in Europe. This article presents the up-to-date legal regulations that are effective in Poland, taking into account their relevance to the issue of vaccinations in migrant population. The analysis of the Polish legislation concerning this problem shows that there are no specific regulations addressed to migrant population staying in our country. This issue seems to be popular in the European Union, where immunization of migrants is given high priority. From the point of view of health care professionals it is important to be aware of the fact that EU open borders favor the increased flow of people between countries. The scale of migration from outside the EU to its member states also contributes to the increase in potential contacts between health care workers and migrants working in Poland.

  9. Assembly of the CMS HF (hadron forward) calorimeter, April 2003 to June 2005

    CERN Multimedia

    Tejinder S. Virdee, CERN

    2005-01-01

    The forward calorimeters (HF) of the CMS hadron calorimeter system are located 11.2 m from the interaction point. Each HF module is composed by 18 wedges, made of steel absorbers and radiation-hard quartz fibers. The photogallery shows the wedges (Figs. 1-3, April 2003), the assembly of one HF module (Figs. 4-9, May and June 2004) and the assembly of the other (Figs. 10-11, June 2005)

  10. 2005 Status Report Savings Estimates for the ENERGY STAR(R)Voluntary Labeling Program

    Energy Technology Data Exchange (ETDEWEB)

    Webber, Carrie A.; Brown, Richard E.; Sanchez, Marla

    2006-03-07

    ENERGY STAR(R) is a voluntary labeling program designed toidentify and promote energy-efficient products, buildings and practices.Operated jointly by the Environmental Protection Agency (EPA) and theU.S. Department of Energy (DOE), Energy Star labels exist for more thanforty products, spanning office equipment, residential heating andcooling equipment, commercial and residential lighting, home electronics,and major appliances. This report presents savings estimates for a subsetof ENERGY STAR labeled products. We present estimates of the energy,dollar and carbon savings achieved by the program in the year 2004, whatwe expect in 2005, and provide savings forecasts for two marketpenetration scenarios for the periods 2005 to 2010 and 2005 to 2020. Thetarget market penetration forecast represents our best estimate of futureENERGY STAR savings. It is based on realistic market penetration goalsfor each of the products. We also provide a forecast under the assumptionof 100 percent market penetration; that is, we assume that all purchasersbuy ENERGY STAR-compliant products instead of standard efficiencyproducts throughout the analysis period.

  11. Economic evaluation of delivering Haemophilus influenzae type b vaccine in routine immunization services in Kenya.

    Science.gov (United States)

    Akumu, Angela Oloo; English, Mike; Scott, J Anthony G; Griffiths, Ulla K

    2007-07-01

    Haemophilus influenzae type b (Hib) vaccine was introduced into routine immunization services in Kenya in 2001. We aimed to estimate the cost-effectiveness of Hib vaccine delivery. A model was developed to follow the Kenyan 2004 birth cohort until death, with and without Hib vaccine. Incidence of invasive Hib disease was estimated at Kilifi District Hospital and in the surrounding demographic surveillance system in coastal Kenya. National Hib disease incidence was estimated by adjusting incidence observed by passive hospital surveillance using assumptions about access to care. Case fatality rates were also assumed dependent on access to care. A price of US$ 3.65 per dose of pentavalent diphtheria-tetanus-pertussis-hep B-Hib vaccine was used. Multivariate Monte Carlo simulations were performed in order to assess the impact on the cost-effectiveness ratios of uncertainty in parameter values. The introduction of Hib vaccine reduced the estimated incidence of Hib meningitis per 100,000 children aged disability adjusted life year (DALY) and per discounted death averted were US$ 38 (95% confidence interval, CI: 26-63) and US$ 1197 (95% CI: 814-2021) respectively. Most of the uncertainty in the results was due to uncertain access to care parameters. The break-even pentavalent vaccine price--where incremental Hib vaccination costs equal treatment costs averted from Hib disease--was US$ 1.82 per dose. Hib vaccine is a highly cost-effective intervention in Kenya. It would be cost-saving if the vaccine price was below half of its present level.

  12. The capsular group B meningococcal vaccine, 4CMenB : clinical experience and potential efficacy.

    Science.gov (United States)

    Rollier, Christine S; Dold, Christina; Marsay, Leanne; Sadarangani, Manish; Pollard, Andrew J

    2015-01-01

    Capsular group B meningococcal disease is a leading cause of childhood meningitis and septicaemia. Up to 10% of sufferers die, and sequelae remain in > 30% of survivors. A vaccine, four component meningococcal group B ( 4CMenB ), designed with the aim to induce broad coverage against this highly variable bacterium, has been licensed in countries including in the European Union, Canada and Australia. Immunogenicity and safety data, published in peer-reviewed literature between 2004 and 2014, are presented in the context of the recent recommendation for the use of the vaccine in infants in the UK. 4CMenB induces significant reactogenicity when administered with routine infant vaccines, in particular with respect to fever rates. Fevers can be somewhat reduced using paracetamol. The efficacy of the vaccine is unknown but has been extrapolated from effectiveness data obtained from use of one of its components in New Zealand, immunogenicity data from clinical trials and estimation of coverage from in vitro studies. These data suggest that the vaccine will prevent a proportion of invasive meningococcal disease cases in infants and young children. Implementation and well-planned post-marketing surveillance will address uncertainties over field effectiveness.

  13. Outbreak of rotavirus gastroenteritis with high mortality, Nicaragua, 2005 Brote de gastroenteritis por rotavirus con alta mortalidad, Nicaragua, 2005

    Directory of Open Access Journals (Sweden)

    Juan José Amador

    2008-04-01

    Full Text Available OBJECTIVES: We investigated a nationwide outbreak of severe rotavirus gastroenteritis in Nicaragua in children under 5 years old, leading to many consultations, hospitalizations, and deaths. We questioned whether a vaccine might have prevented these illnesses and deaths, sought to identify risk factors for death, and developed a clinical profile of children hospitalized with diarrhea. METHODS: We conducted a case-control study to determine whether children who died had access to routine immunizations, a proxy predicting access to a rotavirus vaccine. We identified risk factors for death among children who died in the outbreak compared with surviving age-matched controls with diarrhea. We collected stools, clinical data, and immunization data on children hospitalized for diarrhea to test for rotavirus, develop the profile, and forecast future access to a rotavirus vaccine. RESULTS: The outbreak from February to April 2005 caused 47 470 consultations and 52 deaths. Approximately 80% of cases and controls and 60% of children hospitalized with diarrhea had access to routine immunizations and would likely have had access to a rotavirus vaccine. With a vaccine efficacy of 85%, up to 51% of severe rotavirus cases and up to 68% of deaths could have been prevented if a rotavirus vaccine were available as part of routine child-hood immunizations. Study of 35 case-control pairs indicated that severe illnesses, malnutrition, and care by traditional healers were risk factors for death. Rotavirus was found in 42% of samples from hospitalized children and was associated with severe disease and dehydration. CONCLUSIONS: The impact of the seasonal outbreaks of rotavirus disease could be diminished with a rotavirus vaccine, improvements in oral rehydration programs, and training of traditional healers in the proper management of children with acute diarrhea.OBJETIVOS: Se investigó un brote nacional de gastroenteritis grave por rotavirus en niños menores de 5 a

  14. Brood Year 2004: Johnson Creek Chinook Salmon Supplementation Report, June 2004 through March 2006.

    Energy Technology Data Exchange (ETDEWEB)

    Gebhards, John S.; Hill, Robert; Daniel, Mitch [Nez Perce Tribe

    2009-02-19

    The Nez Perce Tribe, through funding provided by the Bonneville Power Administration, has implemented a small scale chinook salmon supplementation program on Johnson Creek, a tributary in the South Fork of the Salmon River, Idaho. The Johnson Creek Artificial Propagation Enhancement project was established to enhance the number of threatened Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha) returning to Johnson Creek to spawn through artificial propagation. This was the sixth season of adult chinook broodstock collection in Johnson Creek following collections in 1998, 2000, 2001, 2002, and 2003. Weir installation was completed on June 21, 2004 with the first chinook captured on June 22, 2004 and the last fish captured on September 6, 2004. The weir was removed on September 18, 2004. A total of 338 adult chinook, including jacks, were captured during the season. Of these, 211 were of natural origin, 111 were hatchery origin Johnson Creek supplementation fish, and 16 were adipose fin clipped fish from other hatchery operations and therefore strays into Johnson Creek. Over the course of the run, 57 natural origin Johnson Creek adult chinook were retained for broodstock, transported to the South Fork Salmon River adult holding and spawning facility and held until spawned. The remaining natural origin Johnson Creek fish along with all the Johnson Creek supplementation fish were released upstream of the weir to spawn naturally. Twenty-seven Johnson Creek females were artificially spawned with 25 Johnson Creek males. Four females were diagnosed with high bacterial kidney disease levels resulting in their eggs being culled. The 27 females produced 116,598 green eggs, 16,531 green eggs were culled, with an average eye-up rate of 90.6% resulting in 90,647 eyed eggs. Juvenile fish were reared indoors at the McCall Fish Hatchery until November 2005 and then transferred to the outdoor rearing facilities during the Visual Implant Elastomer tagging operation

  15. Immunoinformatics of Placental Malaria Vaccine Development

    DEFF Research Database (Denmark)

    Jessen, Leon Eyrich

    Malaria is an infectious disease caused by a protozoan parasite of the genus Plasmodium, which is transferred by female Anopheles mosquitos. WHO estimates that in 2012 there were 207 million cases of malaria, of which 627,000 were fatal. People living in malaria-endemic areas, gradually acquire...... immunity with multiple infections. Placental malaria (PM) is caused by P. falciparum sequestering in the placenta of pregnant women due to the presence of novel receptors in the placenta. An estimated 200,000 infants die a year as a result of PM. In 2004 the specific protein responsible...... and development in the field of placental malaria vaccine development....

  16. Preparation and characterization of water-absorbing composite ...

    African Journals Online (AJOL)

    ABCO

    2012-08-16

    Aug 16, 2012 ... 2007; Doorkosh et al., 2000), and natural polymers (Yu et al., 2009; Doorkosh et al., ... Zhang et al., 2007; Lee and Chen, 2005; Neaman et al.,. 2004; Lin et al., 2001). ..... Li A, Zhang JP, Wang AQ (2007). Utilization of starch ...

  17. Azure Dynamics Corporation annual report 2004

    International Nuclear Information System (INIS)

    2005-01-01

    Azure Dynamics Corporation is an international leader in the development of proprietary hybrid electric vehicles (HEV) and electric powertrains. In 2004, the company moved its Canadian operations to Vancouver where it can develop and test its technology. Azure has developed HEV technology for the light to medium duty commercial vehicle category. In particular, its main business is the commercialization of HEV and electric vehicle (EV) control and powertrain systems for commercial vehicles (ACS Technology). In 2004, Azure announced an agreement with British-based Leyland Product Development, Zebra Batteries and Renault Trucks to produce a master electric delivery van. It also introduced the first hybrid electric taxi in London and delivered 30 vehicles in the initial phase of an agreement with Purolator that could see delivery of up to 2,000 vehicles. Azure also acquired Solectria Corporation in the United States and is currently developing a powertrain platform for vehicles in the medium-duty weight range of 7,500 to 14,000 pounds gross vehicle weight, and another powertrain for vehicles in the light-duty weight range of 5,000 to 7,5000 pounds gross vehicle weight. Commercial sales of its product is targeted for 2005. This annual report includes information on the company's net earnings and investor profiles, and includes consolidated financial statements and common share information such as assets, liabilities, revenues, expenses and cash flows. tabs., figs

  18. Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis

    OpenAIRE

    Wilson, Kumanan; Hawken, Steven; Kwong, Jeffrey C.; Deeks, Shelley; Crowcroft, Natasha S.; Van Walraven, Carl; Potter, Beth K.; Chakraborty, Pranesh; Keelan, Jennifer; Pluscauskas, Michael; Manuel, Doug

    2011-01-01

    BACKGROUND: Live vaccines have distinct safety profiles, potentially causing systemic reactions one to 2 weeks after administration. In the province of Ontario, Canada, live MMR vaccine is currently recommended at age 12 months and 18 months. METHODS: Using the self-controlled case series design we examined 271,495 12 month vaccinations and 184,312 18 month vaccinations to examine the relative incidence of the composite endpoint of emergency room visits or hospital admissions in consecutive o...

  19. Eimeria Oocyst Concentrations and Species Composition in Litter from Commercial Broiler Farms During Anticoccidial Drug or Live Eimeria Oocyst Vaccine Control Programs.

    Science.gov (United States)

    Jenkins, Mark C; Parker, Carolyn; Ritter, Donald

    2017-06-01

    The purpose of this study was to determine if Eimeria oocyst concentrations and species composition in commercial broiler house litter changed during different cycles of anticoccidial drug (ACD) or live Eimeria oocyst vaccine (VAC) control programs and if there was a correlation between Eimeria oocyst levels and broiler performance. Litter samples were collected from a total of 15 different broiler farms encompassing a total of 45 individual houses during at least one complete grow-out cycle over a 21-mo period. Of these 15 broiler farms, three were followed for the entire 21-mo period spanning three ACD and four VAC cycles. Samples were collected at 2, 4, and 7-8 wk of grow-out corresponding to starter, grower, and withdraw periods of the ACD cycle. On a number of occasions, litter samples were obtained just prior to chick placement. Eimeria oocysts were isolated from all samples, counted by microscopy, and extracted for DNA to identify Eimeria species by ITS1 PCR. In general, Eimeria oocyst concentration in litter reached peak levels at 2-4 wk of grow-out regardless of coccidiosis control measure being used. However, peak oocyst numbers were sometimes delayed until 7-8 wk, indicating some level of Eimeria spp. drug resistance or incomplete vaccine coverage. Eimeria maxima , Eimeria acervulina , Eimeria praecox, and Eimeria tenella were generally present in all samples, and no difference in the species composition was noted between houses on a particular farm. While Eimeria species composition was similar among houses, Eimeria spp. oocyst levels exhibited sporadic peaks in one house of a given location's houses. Of particular interest was the observed correlation between E. maxima oocyst abundance and chick mortality. However, no correlation was observed in E. maxima oocyst levels, and the performance parameters adjusted feed conversion ratio and average daily weight gain. This study showed that understanding the dynamics of Eimeria spp. oocyst levels and species

  20. Spokane Tribal Hatchery, 2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peone, Tim L. (Spokane Tribe of Indians, Wellpinit, WA)

    2006-03-01

    Due to the construction and operation of Grand Coulee Dam (1939), anadromous salmon have been eradicated and resident fish populations permanently altered in the upper Columbia River region. Federal and private hydropower dam operations throughout the Columbia River system severely limits indigenous fish populations in the upper Columbia. Artificial production has been determined appropriate for supporting harvestable fisheries for kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) in Lake Roosevelt and Banks Lake (Grand Coulee Dam impoundments). The Spokane Tribe, Washington Department of Fish and Wildlife, Colville Confederated Tribes and Lake Roosevelt Development Association/Lake Roosevelt Volunteer Net Pen Project are cooperating in a comprehensive artificial production program to produce kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) for annual releases into the project area. The program consists of the Spokane Tribal Hatchery, Sherman Creek Hatchery, Ford Trout Hatchery and Lake Roosevelt Rainbow Trout Net Pen Rearing Projects. The Lake Roosevelt and Banks Lake Fisheries Evaluation Program monitor and evaluates release strategies and production methods for the aforementioned projects. Between 1985 and 2005 the projects have collectively produced up to 800,000 rainbow trout and 4 million kokanee salmon for release into Lake Roosevelt and 1.4 million kokanee fry for Banks Lake annually. In 2005, the annual release goal included 3.3 million kokanee fry, 475,000 kokanee yearlings and 500,000 rainbow trout yearlings. Fish produced by this project in 2005 to meet collective fish production and release goals included: 3,446,438 kokanee fingerlings, 347,730 rainbow trout fingerlings and 525,721 kokanee yearlings. Kokanee yearlings were adipose fin clipped before release. Stock composition consisted of Meadow Creek and Lake Whatcom kokanee, diploid-triploid Spokane Trout Hatchery (McCloud River) rainbow trout and